Digital Semaphore: Tactical Implications of QR Code Optical Signaling for Fleet Communications
2013-06-01
Emissions Control (EMCON) and Hazards of Electromagnetic Radiation to Ordnance (HERO) restrict the ability for Naval Vessels to communicate using...importance of visual communications methods is brought to light by discussing emissions control, hazards of electromagnetic radiation to ordnance , and...overview of emissions restrictions including Emissions Control (EMCON) and Hazards of Electromagnetic Radiation to Ordnance (HERO). Chapter VII is
Bi-Level Demand-Sensitive LED Street Lighting Systems
2013-10-01
Hazards of Electromagnetic Radiation to Fuel HERO : Hazards of Electromagnetic Radiation to Ordnance ...we followed the following guidelines very strictly: 68 • For Hazards of Electromagnetic Radiation to Ordnance (HERO), RF device to be brought in...should be used at least 5 feet from ordnance /explosives. • For, Hazards of Electromagnetic Radiation to Personnel (HERP), HERP Controlled and
10 CFR 835.901 - Radiation safety training.
Code of Federal Regulations, 2011 CFR
2011-01-01
....901(c) commensurate with the hazards in the area and the required controls: (1) Before being permitted... controls, by successful completion of an examination and performance demonstrations: (1) Before being... radiological hazards: (1) Risks of exposure to radiation and radioactive materials, including prenatal...
Application of systems and control theory-based hazard analysis to radiation oncology.
Pawlicki, Todd; Samost, Aubrey; Brown, Derek W; Manger, Ryan P; Kim, Gwe-Ya; Leveson, Nancy G
2016-03-01
Both humans and software are notoriously challenging to account for in traditional hazard analysis models. The purpose of this work is to investigate and demonstrate the application of a new, extended accident causality model, called systems theoretic accident model and processes (STAMP), to radiation oncology. Specifically, a hazard analysis technique based on STAMP, system-theoretic process analysis (STPA), is used to perform a hazard analysis. The STPA procedure starts with the definition of high-level accidents for radiation oncology at the medical center and the hazards leading to those accidents. From there, the hierarchical safety control structure of the radiation oncology clinic is modeled, i.e., the controls that are used to prevent accidents and provide effective treatment. Using STPA, unsafe control actions (behaviors) are identified that can lead to the hazards as well as causal scenarios that can lead to the identified unsafe control. This information can be used to eliminate or mitigate potential hazards. The STPA procedure is demonstrated on a new online adaptive cranial radiosurgery procedure that omits the CT simulation step and uses CBCT for localization, planning, and surface imaging system during treatment. The STPA procedure generated a comprehensive set of causal scenarios that are traced back to system hazards and accidents. Ten control loops were created for the new SRS procedure, which covered the areas of hospital and department management, treatment design and delivery, and vendor service. Eighty three unsafe control actions were identified as well as 472 causal scenarios that could lead to those unsafe control actions. STPA provides a method for understanding the role of management decisions and hospital operations on system safety and generating process design requirements to prevent hazards and accidents. The interaction of people, hardware, and software is highlighted. The method of STPA produces results that can be used to improve safety and prevent accidents and warrants further investigation.
He, Jia-xi; Zhou, Wei; Qiu, Hai-li; Yang, Guang-tao
2013-12-01
To investigate the non-ionizing radiation hazards from physiotherapy equipment in medical institutions and to explore feasible control measures for occupational diseases. On-site measurement and assessment of ultra-high-frequency radiation, high-frequency electromagnetic field, microwave radiation, and laser radiation were carried out in 16 medical institutions using the methods in the Measurement of Physical Agents in Workplace (GBZ/T189-2007). All the investigated medical institutions failed to take effective protective measures against non-ionizing radiation. Of the 17 ultra-short wave therapy apparatus, 70.6%, 47.1%, and 17.64% had a safe intensity of ultra-high-frequency radiation on the head, chest, and abdomen, respectively. Of the 4 external high-frequency thermotherapy apparatus, 100%, 75%, and 75%had a safe intensity of high-frequency electromagnetic field on the head, chest, and abdomen, respectively. In addition, the intensities of microwave radiation and laser radiation produced by the 18 microwave therapy apparatus and 12 laser therapeutic apparatus met national health standards. There are non-ionizing radiation hazards from physiotherapy equipment in medical institutions, and effective prevention and control measures are necessary.
Apollo experience report: Protection against radiation
NASA Technical Reports Server (NTRS)
English, R. A.; Benson, R. E.; Bailey, J. V.; Barnes, C. M.
1973-01-01
Radiation protection problems on earth and in space are discussed. Flight through the Van Allen belts and into space beyond the geomagnetic shielding was recognized as hazardous before the advent of manned space flight. Specialized dosimetry systems were developed for use on the Apollo spacecraft, and systems for solar-particle-event warning and dose projection were devised. Radiation sources of manmade origin on board the Apollo spacecraft present additional problems. Methods applied to evaluate and control or avoid the various Apollo radiation hazards are discussed.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Askin, A.; Buddemeier, B.; Alai, M.
In support of the Department of Energy (DOE) National nuclear Security Administration (NNSA) and the Centers for Disease Control and Prevention (CDC), Lawrence Livermore National Laboratory (LLNL) assisted in the development of new data templates for disseminating and communicating FRMAC1 data products using the CDC Radiation Hazard Scale communication tool. To ensure these data products will be useful to stakeholders during a radiological emergency, LLNL facilitated opportunities for product socialization and review.
Kennedy Space Center Environmental Health Program
NASA Technical Reports Server (NTRS)
Creech, Joanne W.
1997-01-01
Topic considered include: environmental health services; health physics; ionizing radiation; pollution control; contamination investigations; natural resources; surface water; health hazard evaluations; combustion gas; launch support; asbestos; hazardous noise; and ventilation.
Compliance of SLAC_s Laser Safety Program with OSHA Requirements for the Control of Hazardous Energy
DOE Office of Scientific and Technical Information (OSTI.GOV)
Woods, Michael; /SLAC
SLAC's COHE program requires compliance with OSHA Regulation 29CFR1910.147, 'The control of hazardous energy (lockout/tagout)'. This regulation specifies lockout/tagout requirements during service and maintenance of equipment in which the unexpected energization or start up of the equipment, or release of stored energy, could cause injury to workers. Class 3B and Class 4 laser radiation must be considered as hazardous energy (as well as electrical energy in associated equipment, and other non-beam energy hazards) in laser facilities, and therefore requires careful COHE consideration. This paper describes how COHE is achieved at SLAC to protect workers against unexpected Class 3B or Classmore » 4 laser radiation, independent of whether the mode of operation is normal, service, or maintenance.« less
Integration and Validation of Avian Radars (IVAR)
2011-08-01
hazards of electromagnetic radiation to fuel HERO hazards of electromagnetic radiation to ordnance HERP hazards ... hazard Radiation hazard to humans, fuels, and ordnance can be easily managed. Demonstration of how operation of radars can meet hazards of... electromagnetic radiation to personnel (HERP), hazards of electromagnetic radiation to
Federal Guidance Report No. 8: Guidance for the Control of Radiation Hazards in Uranium Mining
This report contains background material used in the development of guidance concerning radiation protection in the mining of uranium ore, and seeks to provide guidance for long-term radiation protection in uranium mining.
Electromagnetic Radiation Hazards Testing for Non-Ionizing Radio Frequency Transmitting Equipment
2012-12-19
Hazards of Electromagnetic Radiation to Ordnance (HERO), Personnel (HERP), and Fuel (HERF) protection guidance for intentional non-ionizing Radio...HERO Hazards of Electromagnetic Radiation to Ordnance HERP Hazards of Electromagnetic Radiation to Personnel IEEE Institute of Electrical and...Systems Command Technical Manual, Electromagnetic Radiation Hazards ( Hazards to Ordnance ), 1 July 2008.
[Working environment measurement of radioactive substances].
Kunugita, Naoki
2007-12-01
The control of the working environment is one of the most important duties in any working place to prevent occupational disease. In Japan, in the case of the controlled area using unsealed radioisotopes, the measurement of the concentration of airborne radioactive substances should be carried out under the regulations of the "Industrial Safety and Health Law" and the "Ordinance on Prevention of Ionizing Radiation Hazards". Many reports showed that the results of regular working environment measurements of radioactive substances were about background levels. Safe working environments are sufficiently guaranteed by a suitable estimation and handling under the strict regulation by the "Laws Concerning the Prevention from Radiation Hazards Due to Radioisotopes and Others". The regulation by "Ordinance on Prevention of Ionizing Radiation Hazards" would be relaxed in the field of education and research, which use very low quantities of radioactive substances, in ways such as estimation by calculation in place of the actual measurement, decrease of the number of monthly measurements, and measurement exemption for low levels of isotopes.
Architecting the Safety Assessment of Large-scale Systems Integration
2009-12-01
Electromagnetic Radiation to Ordnance ( HERO ) Hazards of Electromagnetic Radiation to Fuel (HERF) The main reason that this particular safety study... radiation , high voltage electric shocks and explosives safety. 1. Radiation Hazards (RADHAZ) RADHAZ describes the hazards of electromagnetic radiation ...OP3565/NAVAIR 16-1-529 [19 and 20], these hazards are segregated as follows: Hazards of Electromagnetic
Joint Electromagnetic Spectrum Management Operations
2012-03-20
electromagnetic radiation to ordnance ( HERO ), hazards of electromagnetic radiation to fuels (HERF), and natural phenomena effects of lightning and...fuels HERO hazards of electromagnetic radiation to ordnance HERP hazards of electromagnetic radiation to personnel HF high frequency HN host... electromagnetic pulse (EMP); hazards of EM radiation to personnel, ordnance ,
The implementation of physical safety system in bunker of the electron beam accelerator
NASA Astrophysics Data System (ADS)
Ahmad, M. A.; Hashim, S. A.; Ahmad, A.; Leo, K. W.; Chulan, R. M.; Dalim, Y.; Baijan, A. H.; Zain, M. F.; Ros, R. C.
2017-01-01
This paper describes the implementation of physical safety system for the new low energy electron beam (EB) accelerator installed at Block 43T Nuclear Malaysia. The low energy EB is a locally designed and developed with a target energy of 300 keV. The issues on radiation protection have been addressed by the installation of radiation shielding in the form of a bunker and installation radiation monitors. Additional precaution is needed to ensure that personnel are not exposed to radiation and other physical hazards. Unintentional access to the radiation room can cause serious hazard and hence safety features must be installed to prevent such events. In this work we design and built a control and monitoring system for the shielding door. The system provides signals to the EB control panel to allow or prevent operation. The design includes limit switches, key-activated switches and emergency stop button and surveillance camera. Entry procedure is also developed as written record and for information purposes. As a result, through this safety implementation human error will be prevented, increase alertness during operation and minimizing unnecessary radiation exposure.
Optical radiation hazards of laser welding processes. Part II: CO2 laser.
Rockwell, R J; Moss, C E
1989-08-01
There has been an extensive growth within the last five years in the use of high-powered lasers in various metalworking processes. The two types of lasers used most frequently for laser welding/cutting processes are the Neodymium-yttrium-aluminum-garnet (Nd:YAG) and the carbon dioxide (CO2) systems. When such lasers are operated in an open beam configuration, they are designated as a Class IV laser system. Class IV lasers are high-powered lasers that may present an eye and skin hazard under most common exposure conditions, either directly or when the beam has been diffusely scattered. Significant control measures are required for unenclosed (open beam), Class IV laser systems since workers may be exposed to scattered or reflected beams during the operation, maintenance, and service of these lasers. In addition to ocular and/or skin exposure hazards, such lasers also may present a multitude of nonlaser beam occupational concerns. Radiant energy measurements are reported for both the scattered laser radiation and the plasma-related plume radiations released during typical high-powered CO2 laser-target interactions. In addition, the application of the nominal hazard zone (NHZ) and other control measures also are discussed with special emphasis on Class IV industrial CO2 laser systems.
Hazards of Electromagnetic Radiation to Ordnance (HERO) Safety Test
2013-01-10
Ordnance Test Procedure (JOTP)-061 Hazards of Electromagnetic Radiation to...DEPARTMENT OF DEFENSE JOINT ORDNANCE TEST PROCEDURE (JOTP)-061 HAZARDS OF ELECTROMAGNETIC RADIATION TO ORDNANCE (HERO) SAFETY...TEST Joint Services Munition Safety Test Working Group Joint Ordnance Test Procedure (JOTP)-061 Hazards of Electromagnetic Radiation
77 FR 23803 - Office of Hazardous Materials Safety; Actions on Special Permit Applications
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-20
... MODIFICATION SPECIAL PERMIT GRANTED 8826-M Phoenix Air 49 CFR 172.101; To modify the Group, Inc. 172.204(c)(3...-M......... Conference of 49 CFR To modify the Radiation 172.203(d); special permit add Control Part............ Conference of 49 CFR Part To modify the Radiation 172, Subparts, special permit add Control C, D, E, F, G, 49...
10 CFR 33.15 - Requirements for the issuance of a Type C specific license of broad scope.
Code of Federal Regulations, 2011 CFR
2011-01-01
... bachelor level, or equivalent training and experience, in the physical or biological sciences or in..., radiation detection instrumentation, and biological hazards of exposure to radiation appropriate to the type... controls and provisions relating to procurement of byproduct material, procedures, record keeping, material...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-08
..., TX. 8826-M Phoenix Air 4 03-31-2012 Group, Inc., Cartersville, GA. 12561-M Rhodia, Inc., 4 03-31-2012... Clark Air, 4 03-31-2012 Inc., Port Alsworth, AK. 10656-M Conference of 4 03-31-2012 Radiation Control... Conference of 4 03-31-2012 Radiation Control, Program Directors, Inc., Frankfort, KY. 10898-M Hydac 3 03-31...
Injury control in practice. Home radiator burns in inner-city children.
Quinlan, K P
1996-09-01
To describe thermal burns from radiators in the homes of children in the inner city and an intervention to decrease the risk for this pediatric injury. Academic medical center in Chicago. Case series of 10 radiator-related burns. The burns described were found to be clustered in an area of a public housing project served by steam radiators. No burns were associated with hot water radiators. Just 14% of housing units with young children had adequate radiator covers and radiator pipe insulation. Radiator covers and insulation have now been replaced or repaired in all units of the 11 housing project buildings served by steam radiators. Steam radiators in the home represent a particular childhood burn hazard. Community-based clinicians are in a unique position to recognize local patterns of injury and work with other agencies in injury control efforts.
NASA Astrophysics Data System (ADS)
Idriss, Hajo; Salih, Isam; Alaamer, Abdulaziz S.; AL-Rajhi, M. A.; Osman, Alshfia; Adreani, Tahir Elamin; Abdelgalil, M. Y.; Ali, Nagi I.
2018-06-01
This study shows the assessment of radiation hazard parameters due to terrestrial radionuclides in the soil around artisanal gold mining for addressing the issue of natural radioactivity in mining areas. Hence, the levels 238U, 232Th, 40K and 226Ra in soil (using gamma spectrometry), 222Rn in soil and 222Rn in air were determined. Radiation hazard parameters were then computed. These include absorbed dose D, annual effective dose E, radium equivalent activity Raeq, external hazard H ex, annual gonadal dose equivalent hazard index AGDE and excess lifetime cancer risk ELCR due to the inhalation of radon (222Rn) and consumption of radium (226Ra) in vegetation. Uranium (238U), thorium (232Th) and potassium (40K) averages were, respectively, 26, 36 and 685 Becquerel per kilogram (Bq kg-1). Soil radon (4671 Bq m-3) and radon in air (14.77 Bq m-3) were found to be less than worldwide data. Nevertheless, the average 40K concentration was 685 Bq kg-1. This is slightly higher than the United Nations Scientific Committee on the Effects of Atomic Radiation average value of 412 Bq kg-1. The obtained result indicates that some of the radiation hazard parameters seem unsavory. The mean value of absorbed dose rate (62.49 nGy h-1) was slightly higher than average value of 57 nGy h-1 ( 45% from 40K), and that of AGDE (444 μSv year-1) was higher than worldwide average reported value (300 μSv year-1). This study highlights the necessity to launch extensive nationwide radiation protection program in the mining areas for regulatory control.
Special requirements for electronics to be used in robots in space
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sias, F.R.
1994-12-31
Robots have been developed for use in hazardous environments and space certainly falls in the category of a hazardous environment. Microcomputers and electronics used to control robotic systems to be employed in space face greater threats than earth-bound robots used around radioactive materials. It is well known that nuclear radiation damages semiconductor devices by causing charges to build up in silicon dioxide insulating layers when the devices are exposed to ionizing radiation. Electronics suffer from doses of radiation when used around radioactive materials; however, additional sources of damage are present when the robots are used in space. This paper ismore » a review of the problems that must be considered when developing electronics for robots to be used in space and some of the available solutions.« less
Base-Level Guide for Electromagnetic Frequency Radiation
2012-12-01
hazards of EMF-producing systems and equipment, e.g., hazard of electromagnetic radiation to ordnance (HERO), and hazard ...AFRL-SA-WP-SR-2013-0003 BASE-LEVEL GUIDE FOR ELECTROMAGNETIC FREQUENCY RADIATION Matthew W. Uelen Battelle Memorial Institute...COVERED (From – To) Dec 2011 – Dec 2012 4. TITLE AND SUBTITLE Base-Level Guide for Electromagnetic Frequency Radiation 5a. CONTRACT NUMBER
RCT: Module 2.11, Radiological Work Coverage, Course 8777
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hillmer, Kurt T.
2017-07-20
Radiological work is usually approved and controlled by radiation protection personnel by using administrative and procedural controls, such as radiological work permits (RWPs). In addition, some jobs will require working in, or will have the potential for creating, very high radiation, contamination, or airborne radioactivity areas. Radiological control technicians (RCTs) providing job coverage have an integral role in controlling radiological hazards. This course will prepare the student with the skills necessary for RCT qualification by passing quizzes, tests, and the RCT Comprehensive Phase 1, Unit 2 Examination (TEST 27566) and will provide in-the-field skills.
2009-01-01
Hazards of Electromagnet - ic Radiation to Ordnance ( HERO ). Below decks spaces, such as ammunition storage lockers and...Navy’s Hazards of Electromagnetic Radiation to Ordnance ( HERO ) program. Unlike other services deployed in our nation’s defense, our sailors liter...also provides infor- mation on other general HERO requirements. The Electromagnetic Radiation Hazards ( Hazards to Ordnance ) Datasheets2
Sushko, V O; Nezgovorova, G A; Degtjarova, L V; Kolosynska, O O; Gromadska, V M
2015-12-01
Аim: The determination of morphological features of stomach and duodenum mucous of membrane (MM) damage at a personnel that works in radiation hazard conditions at the object of "Shelter" of Chornobyl NPP (OS) by the endoscopic monitoring with biopsy material inspection from a gastro-duodenal zone on the stages of check - in (InC) and the special medical control (SpC). the complex clinical-endoscopic and morphological examination with the biopsy of MM of stomach and duodenum in 126 workers of OS (man in the age from 20 to 59) was carried out. Doses of external radiation exposure were from 0,14 to 79,6 mSv, доза internal radiation exposure were from 0,1 to 3 mSv/Results: For the personnel of OS contract organisations differently directed pathomorphological changes of MM at InC and increase of frequency of their exposure at an inspection during SC, that generally correspond to chronic H.pylori-associated pangastritis with violation of microcirculation and trophism, disregeneration changes of epithelial layer. for the personnel of contract organizations, which participated in radiation hazard works on ОS a presence of chronic H.pylori-associated pangastritis with the increase of frequency of atrophic changes of MM (nonmetaplastic or metaplastic type) and development of erosive-ulcerous defects of gastro-duodenal zone was founded out.For workers, who had previous influence of ionizing irradiation the greater frequency of disregeneration (hyperplasia / intestinal metaplasia) changes of epithelium that accordingly promotes the risk of neoplasmes transformations was clarified.Providing of EGDFS (at a necessity with the biopsy of MM) is at InC and next stages of medical control for personnel, that executes radiation hazard works on ОS is the highly informative evidential and necessary method of inspection for determination of form and degree of pathological changes of overhead departments of gastrointestinal tract for warning of progress of disease and development of complications, maintenance of workers health and workability. V. O. Sushko, G. A. Nezgovorova, L. V. Degtjarova, O. O.Kolosynska, V. M.Gromadska.
Spacecraft Charging: Hazard Causes, Hazard Effects, Hazard Controls
NASA Technical Reports Server (NTRS)
Koontz, Steve.
2018-01-01
Spacecraft flight environments are characterized both by a wide range of space plasma conditions and by ionizing radiation (IR), solar ultraviolet and X-rays, magnetic fields, micrometeoroids, orbital debris, and other environmental factors, all of which can affect spacecraft performance. Dr. Steven Koontz's lecture will provide a solid foundation in the basic engineering physics of spacecraft charging and charging effects that can be applied to solving practical spacecraft and spacesuit engineering design, verification, and operations problems, with an emphasis on spacecraft operations in low-Earth orbit, Earth's magnetosphere, and cis-Lunar space.
1975-08-01
memory difficulties. Psychic changes that include unstable mood, hypochondriasis, and anxiety have been observed. Compared to those in control groups ...and extrapyremidal motor systems. The incidence of neurosis was significantly higher than in controls . Experimental physiologic and EEG methods...differentiated from those in the control group and consequently could not be related to their microwave exposure (13). In a study reported by Czerski and
An intelligent inspection and survey robot. Volume 2
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
1995-12-15
Radioactive materials make up a significant part of the hazardous-material inventory of the Department of Energy. Much of the radioactive material will be inspected or handled by robotic systems that contain electronic circuits that may be damaged by gamma radiation and other particles emitted from radioactive material. This report examines several scenarios, the damage that may be inflicted, and methods that may be used to protect radiation-hardened robot control systems. Commercial sources of components and microcomputers that can withstand high radiation exposure are identified.
Electromagnetic Spectrum Test and Evaluation Process
2010-01-01
HERO , hazards of electromagnetic radiation to ordnance ; HERP, hazards of electromagnetic radiation to personnel; HERF, hazards of electromagnetic ... electromagnetic pulse (EMP); electronic protection; electrostatic dis- charge (ESD); hazards of electromagnetic radi- ation to personnel (HERP), ordnance ...including ordnance containing electrically initiated devices, to be mutually compatible in their intended
Hazards protection for space suits and spacecraft
NASA Technical Reports Server (NTRS)
Kosmo, Joseph J. (Inventor); Dawn, Frederic S. (Inventor)
1990-01-01
A flexible multi-layered covering article for protection against the hazards of exposure to the environment of outer space is disclosed. The covering includes an outer layer section comprising an outermost lamina of woven expanded tetrafluoroethylene yarns (Gore Tex) for protecting against abrasion and tearing, an underlying weave of meta-aramid yarns (Nomex) and para-aramid yarns (Kevlar) for particle impart protection, and electrostatic charge dissipation and control system incorporated therein, and a chemical contaminants control barrier applied as a coating. A middle section includes a succession of thermal insulating layers of polymeric thermoplastic or thermoforming material, each of which is coated with a metal deposit of high infra-red emissivity and low solar radiation absorption characteristics and separated from adjacent insulating layers by a low thermal conductance material. The covering further includes a radiation attenuating layer of a tungsten-loaded polymeric elastomer binder for protecting against bremsstrahlung radiation and an inner layer of rip-stop polyester material for abrasion protection. A chloroprene coating may be supplied the polyester-material for added micrometeroid protection. Securing means of low heat conductance material secures the multi-layers together as a laminar composite.
Radiation Effects and Protection for Moon and Mars Missions
NASA Technical Reports Server (NTRS)
Parnell, Thomas A.; Watts, John W., Jr.; Armstrong, Tony W.
1998-01-01
Manned and robotic missions to the Earth's moon and Mars are exposed to a continuous flux of Galactic Cosmic Rays (GCR) and occasional, but intense, fluxes of Solar Energetic Particles (SEP). These natural radiations impose hazards to manned exploration, but also present some constraints to the design of robotic missions. The hazards to interplanetary flight crews and their uncertainties have been studied recently by a National Research Council Committee (Space Studies Board 1996). Considering the present uncertainty estimates, thick spacecraft shielding would be needed for manned missions, some of which could be accomplished with onboard equipment and expendables. For manned and robotic missions, the effects of radiation on electronics, sensors, and controls require special consideration in spacecraft design. This paper describes the GCR and SEP particle fluxes, secondary particles behind shielding, uncertainties in radiobiological effects and their impact on manned spacecraft design, as well as the major effects on spacecraft equipment. The principal calculational tools and considerations to mitigate the radiation effects are discussed, and work in progress to reduce uncertainties is included.
Beliefs about radiation: scientists, the public and public policy.
Jenkins-Smith, Hank C; Silva, Carol L; Murray, Christopher
2009-11-01
Human behavioral responses to potential hazards are mediated by the beliefs held about those hazards. This holds whether the "behavior" under consideration is the provision of advice about the hazard, statements of support for policies that address the hazard, or personal behaviors in response to the hazard. This paper focuses on beliefs about radiation and the implications of those beliefs for views about radiation protection by both scientists and members of the U.S. public. We use data from a large sample of scientists, collected in 2002, and a series of surveys of the U.S. public collected in 2007. Among scientists, we focus on how beliefs about radiation are related to policy prescriptions for radiation protection. Among members of the lay public the focus shifts to the relationship between beliefs about radiation risks and policy preferences for nuclear energy and nuclear waste policy options. The importance of the differences and similarities in the patterns of beliefs of scientists and the lay public are discussed.
Awosan, K J; Ibrahim, Mto; Saidu, S A; Ma'aji, S M; Danfulani, M; Yunusa, E U; Ikhuenbor, D B; Ige, T A
2016-08-01
Use of ionizing radiation in medical imaging for diagnostic and interventional purposes has risen dramatically in recent years with a concomitant increase in exposure of patients and health workers to radiation hazards. To assess the knowledge of radiation hazards, radiation protection practices and clinical profile of health workers in UDUTH, Sokoto, Nigeria. A cross-sectional study was conducted among 110 Radiology, Radiotherapy and Dentistry staff selected by universal sampling technique. The study comprised of administration of standardized semi-structured pre-tested questionnaire (to obtain information on socio-demographic characteristics, knowledge of radiation hazards, and radiation protection practices of participants), clinical assessment (comprising of chest X-ray, abdominal ultrasound and laboratory investigation on hematological parameters), and evaluation of radiation exposure of participants (extracted from existing hospital records on their radiation exposure status). The participants were aged 20 to 65 years (mean = 34.04 ± 8.83), most of them were males (67.3%) and married (65.7%). Sixty five (59.1%) had good knowledge of radiation hazards, 58 (52.7%) had good knowledge of Personal Protective Devices (PPDs), less than a third, 30 (27.3%) consistently wore dosimeter, and very few (10.9% and below) consistently wore the various PPDs at work. The average annual radiation exposure over a 4 year period ranged from 0.0475mSv to 1.8725mSv. Only 1 (1.2%) of 86 participants had abnormal chest X-ray findings, 8 (9.4%) of 85 participants had abnormal abdominal ultrasound findings; while 17 (15.5%) and 11 (10.0%) of 110 participants had anemia and leucopenia respectively. This study demonstrated poor radiation protection practices despite good knowledge of radiation hazards among the participants, but radiation exposure and prevalence of abnormal clinical conditions were found to be low. Periodic in-service training and monitoring on radiation safety was suggested.
Ibrahim, MTO; Saidu, SA; Ma’aji, SM; Danfulani, M; Yunusa, EU; Ikhuenbor, DB; Ige, TA
2016-01-01
Introduction Use of ionizing radiation in medical imaging for diagnostic and interventional purposes has risen dramatically in recent years with a concomitant increase in exposure of patients and health workers to radiation hazards. Aim To assess the knowledge of radiation hazards, radiation protection practices and clinical profile of health workers in UDUTH, Sokoto, Nigeria. Materials and Methods A cross-sectional study was conducted among 110 Radiology, Radiotherapy and Dentistry staff selected by universal sampling technique. The study comprised of administration of standardized semi-structured pre-tested questionnaire (to obtain information on socio-demographic characteristics, knowledge of radiation hazards, and radiation protection practices of participants), clinical assessment (comprising of chest X-ray, abdominal ultrasound and laboratory investigation on hematological parameters), and evaluation of radiation exposure of participants (extracted from existing hospital records on their radiation exposure status). Results The participants were aged 20 to 65 years (mean = 34.04 ± 8.83), most of them were males (67.3%) and married (65.7%). Sixty five (59.1%) had good knowledge of radiation hazards, 58 (52.7%) had good knowledge of Personal Protective Devices (PPDs), less than a third, 30 (27.3%) consistently wore dosimeter, and very few (10.9% and below) consistently wore the various PPDs at work. The average annual radiation exposure over a 4 year period ranged from 0.0475mSv to 1.8725mSv. Only 1 (1.2%) of 86 participants had abnormal chest X-ray findings, 8 (9.4%) of 85 participants had abnormal abdominal ultrasound findings; while 17 (15.5%) and 11 (10.0%) of 110 participants had anemia and leucopenia respectively. Conclusion This study demonstrated poor radiation protection practices despite good knowledge of radiation hazards among the participants, but radiation exposure and prevalence of abnormal clinical conditions were found to be low. Periodic in-service training and monitoring on radiation safety was suggested. PMID:27656470
Radiation Environment Effects on Spacecraft
NASA Technical Reports Server (NTRS)
Ladbury, Ray.
2017-01-01
Space poses a variety of radiation hazards. These hazards pose different risks for different missions depending on the mission environment, duration and requirements. This presentation presents a brief look at several radiation related hazards, including destructive and nondestructive Single-Event Effect, Total Ionizing Dose, Displacement Damage and Spacecraft Charging. The temporal and spatial characteristics for the environments of concern for each are considered.
Spectrum Management and Electromagnetic Environmental Effects (E3) Business Process
2010-05-06
HAZARDS OF ELECTROMAGNETIC RADIATION TO ORDNANCE ( HERO ) SURVEY. XM11: IS THERE A CURRENT ELECTROMAGNETIC INTERFERENCE (EMI) SITE SURVEY. SM & EMI Navy...PERSONNEL (HERP) / FUEL (HERF) SURVEY. XM10: IS THERE A CURRENT HAZARDS OF ELECTROMAGNETIC RADIATION TO ORDNANCE ( HERO ) SURVEY. XM11...OF ALL KNOWN ELECTROMAGNETIC INTERFERENCE (EMI) FIXES INSTALLED ONE YEAR AFTER SURVEY COMPLETION. M05: OF ALL RADIATION HAZARDS
47 CFR 80.83 - Protection from potentially hazardous RF radiation.
Code of Federal Regulations, 2014 CFR
2014-10-01
... radiation. 80.83 Section 80.83 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND... Requirements-Ship Stations § 80.83 Protection from potentially hazardous RF radiation. Any license or renewal application for a ship earth station that will cause exposure to radiofrequency (RF) radiation in excess of...
47 CFR 80.83 - Protection from potentially hazardous RF radiation.
Code of Federal Regulations, 2013 CFR
2013-10-01
... radiation. 80.83 Section 80.83 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND... Requirements-Ship Stations § 80.83 Protection from potentially hazardous RF radiation. Any license or renewal application for a ship earth station that will cause exposure to radiofrequency (RF) radiation in excess of...
47 CFR 80.83 - Protection from potentially hazardous RF radiation.
Code of Federal Regulations, 2010 CFR
2010-10-01
... radiation. 80.83 Section 80.83 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND... Requirements-Ship Stations § 80.83 Protection from potentially hazardous RF radiation. Any license or renewal application for a ship earth station that will cause exposure to radiofrequency (RF) radiation in excess of...
47 CFR 80.83 - Protection from potentially hazardous RF radiation.
Code of Federal Regulations, 2012 CFR
2012-10-01
... radiation. 80.83 Section 80.83 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND... Requirements-Ship Stations § 80.83 Protection from potentially hazardous RF radiation. Any license or renewal application for a ship earth station that will cause exposure to radiofrequency (RF) radiation in excess of...
47 CFR 80.83 - Protection from potentially hazardous RF radiation.
Code of Federal Regulations, 2011 CFR
2011-10-01
... radiation. 80.83 Section 80.83 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND... Requirements-Ship Stations § 80.83 Protection from potentially hazardous RF radiation. Any license or renewal application for a ship earth station that will cause exposure to radiofrequency (RF) radiation in excess of...
Study of Thermal Control Systems for orbiting power systems
NASA Technical Reports Server (NTRS)
Howell, H. R.
1981-01-01
Thermal control system designs were evaluated for the 25 kW power system. Factors considered include long operating life, high reliability, and meteoroid hazards to the space radiator. Based on a cost advantage, the bumpered pumped fluid radiator is recommended for the initial 25 kW power system and intermediate versions up to 50 kW. For advanced power systems with heat rejection rates above 50 kW the lower weight of the advanced heat pipe radiator offsets the higher cost and this design is recommended. The power system payloads heat rejection allocations studies show that a centralized heat rejection system is the most weight and cost effective approach. The thermal interface between the power system and the payloads was addressed and a concept for a contact heat exchanger that eliminates fluid transfer between the power system and the payloads was developed. Finally, a preliminary design of the thermal control system, with emphasis on the radiator and radiator deployment mechanism, is presented.
Software System Architecture Modeling Methodology for Naval Gun Weapon Systems
2010-12-01
Weapon System HAR Hazard Action Report HERO Hazards of Electromagnetic Radiation to Ordnance IOC Initial Operational Capability... radiation to ordnance ; and combinations therein. Equipment, systems, or procedures and processes whose malfunction would hazard the safe manufacturing...NDI Non-Development Item OPEVAL Operational Evaluation ORDALTS Ordnance Alterations O&SHA Operating and Support Hazard Analysis PDA
Experiences from First Top-Off Injection at the Stanford Synchrotron Radiation Lightsource
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bauer, J.M.; Liu, J.C.; Prinz, A.
2009-12-11
As the Stanford Synchrotron Radiation Lightsource (SSRL) of the SLAC National Accelerator Laboratory (SLAC) is moving toward Top-Off injection mode, SLAC's Radiation Protection Department is working with SSRL on minimizing the radiological hazards of this mode. One such hazard is radiation that is created inside the accelerator concrete enclosure by injected beam. Since during Top-Off injection the stoppers that would otherwise isolate the storage ring from the experimental area stay open, the stoppers no longer prevent such radiation from reaching the experimental area. The level of this stray radiation was measured in April 2008 during the first Top-Off injection tests.more » They revealed radiation dose rates of up to 18 microSv/h (1.8 millirem/h) outside the experimental hutches, significantly higher than our goal of 1 microSv/h (0.1 millirem/h). Non-optimal injection increased the measured dose rates by a factor two. Further tests in 2008 indicated that subsequent improvements by SSRL to the injection system have reduced the dose rates to acceptable levels. This presentation describes the studies performed before the Top-Off tests, the tests themselves and their major results (both under initial conditions and after improvements were implemented), and presents the controls being implemented for full and routine Top-Off injection.« less
Artificial Optical Radiation photobiological hazards in arc welding.
Gourzoulidis, G A; Achtipis, A; Topalis, F V; Kazasidis, M E; Pantelis, D; Markoulis, A; Kappas, C; Bourousis, C A
2016-08-01
Occupational Health and Safety (OHS) is associated with crucial social, economic, cultural and technical issues. A highly specialized OHS sector deals with the photobiological hazards from artificial optical radiation (AOR), which is divided into visible light, UV and IR emitted during various activities and which is legally covered by European Directive 2006/25/EC. Among the enormous amount of sources emitting AOR, the most important non-coherent ones to consider for health effects to the whole optical range, are arcs created during metal welding. This survey presents the effort to assess the complicated exposure limits of the Directive in the controlled environment of a welding laboratory. Sensors covering the UV and blue light range were set to measure typical welding procedures reproduced in the laboratory. Initial results, apart from apparently justifying the use of Personal Protective Equipment (PPE) due to even subsecond overexposures measured, also set the basis to evaluate PPE's properties and support an integrated risk assessment of the complex welding environment. These results can also improve workers' and employer's information and training about radiation hazards, which is a crucial OHS demand. Copyright © 2016 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tan, Terence, E-mail: trdtwk@nccs.com.sg; Lim, Wan-Teck; Fong, Kam-Weng
Purpose: To compare survival, tumor control, toxicities, and quality of life of patients with locally advanced nasopharyngeal carcinoma (NPC) treated with induction chemotherapy and concurrent chemo-radiation (CCRT), against CCRT alone. Patients and Methods: Patients were stratified by N stage and randomized to induction GCP (3 cycles of gemcitabine 1000 mg/m{sup 2}, carboplatin area under the concentration-time-curve 2.5, and paclitaxel 70 mg/m{sup 2} given days 1 and 8 every 21 days) followed by CCRT (radiation therapy 69.96 Gy with weekly cisplatin 40 mg/m{sup 2}), or CCRT alone. The accrual of 172 was planned to detect a 15% difference in 5-year overall survival (OS) with a 5%more » significance level and 80% power. Results: Between September 2004 and August 2012, 180 patients were accrued, and 172 (GCP 86, control 86) were analyzed by intention to treat. There was no significant difference in OS (3-year OS 94.3% [GCP] vs 92.3% [control]; hazard ratio 1.05; 1-sided P=.494]), disease-free survival (hazard ratio 0.77, 95% confidence interval 0.44-1.35, P=.362), and distant metastases–free survival (hazard ratio 0.80, 95% confidence interval 0.38-1.67, P=.547) between the 2 arms. Treatment compliance in the induction phase was good, but the relative dose intensity for concurrent cisplatin was significantly lower in the GCP arm. Overall, the GCP arm had higher rates of grades 3 and 4 leukopenia (52% vs 37%) and neutropenia (24% vs 12%), but grade 3 and 4 acute radiation toxicities were not statistically different between the 2 arms. The global quality of life scores were comparable in both arms. Conclusion: Induction chemotherapy with GCP before concurrent chemo-irradiation did not improve survival in locally advanced NPC.« less
Ionizing radiation in earth's atmosphere and in space near earth.
DOT National Transportation Integrated Search
2011-05-01
The Civil Aerospace Medical Institute of the FAA is charged with identifying health hazards in air travel and in : commercial human space travel. This report addresses one of these hazards ionizing radiation. : Ionizing radiation is a subatomic p...
Determination of naturally radioactive elements in chalk sticks by means of gamma spectroscopy
NASA Astrophysics Data System (ADS)
Abd El-Wahab, Magda; Morsy, Zeinab; El-Faramawy, Nabil
2010-04-01
The radiation hazards due to ingestion of chalkboard dust were investigated. Sixteen samples from three different origin fabricates were used. The estimation of radiation hazard indices were based on the evaluation of the concentration activities of the natural radionuclides 238U, 232Th and 40K. The radium equivalent activity, external hazard index, internal hazard index and the annual dose equivalent associated with the radionuclides were calculated and compared with international recommended values to assess the radiation hazard. The values of internal and external radiation hazard indices were found to be less than unity. The annual effective dose rate obtained, E eff, and the annual gonadal dose equivalent (AGDE) are found to be less than the limit of the doses recommended by the International Commission on Radiological Protection for the general public. The analytical results show that besides the main calcium content, some toxic elements, S, Mo and Pb and Ni and Pb, in the Egyptian and imported chalk stocks, respectively, existed.
Determination of naturally radioactive elements in chalk sticks by means of gamma spectroscopy
NASA Astrophysics Data System (ADS)
El-Wahab, Magda Abd; Morsy, Zeinab; El-Faramawy, Nabil
The radiation hazards due to ingestion of chalkboard dust were investigated. Sixteen samples from three different origin fabricates were used. The estimation of radiation hazard indices were based on the evaluation of the concentration activities of the natural radionuclides 238U, 232Th and 40K. The radium equivalent activity, external hazard index, internal hazard index and the annual dose equivalent associated with the radionuclides were calculated and compared with international recommended values to assess the radiation hazard. The values of internal and external radiation hazard indices were found to be less than unity. The annual effective dose rate obtained, Eeff, and the annual gonadal dose equivalent (AGDE) are found to be less than the limit of the doses recommended by the International Commission on Radiological Protection for the general public. The analytical results show that besides the main calcium content, some toxic elements, S, Mo and Pb and Ni and Pb, in the Egyptian and imported chalk stocks, respectively, existed.
WE-G-BRA-06: Application of Systems and Control Theory-Based Hazard Analysis to Radiotherapy
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pawlicki, T; Samost, A; Leveson, N
Purpose: The process of delivering radiation occurs in a complex socio-technical system heavily reliant on human operators. Furthermore, both humans and software are notoriously challenging to account for in traditional hazard analysis models. High reliability industries such as aviation have approached this problem through using hazard analysis techniques grounded in systems and control theory. The purpose of this work is to apply the Systems Theoretic Accident Model Processes (STAMP) hazard model to radiotherapy. In particular, the System-Theoretic Process Analysis (STPA) approach is used to perform a hazard analysis of a proposed on-line adaptive cranial radiosurgery procedure that omits the CTmore » Simulation step and uses only CBCT for planning, localization, and treatment. Methods: The STPA procedure first requires the definition of high-level accidents and hazards leading to those accidents. From there, hierarchical control structures were created followed by the identification and description of control actions for each control structure. Utilizing these control structures, unsafe states of each control action were created. Scenarios contributing to unsafe control action states were then identified and translated into system requirements to constrain process behavior within safe boundaries. Results: Ten control structures were created for this new CBCT-only process which covered the areas of hospital and department management, treatment design and delivery, and vendor service. Twenty three control actions were identified that contributed to over 80 unsafe states of those control actions resulting in over 220 failure scenarios. Conclusion: The interaction of people, hardware, and software are highlighted through the STPA approach. STPA provides a hierarchical model for understanding the role of management decisions in impacting system safety so that a process design requirement can be traced back to the hazard and accident that it is intended to mitigate. Varian Medical Systems, Inc.« less
Darius, S; Meyer, F; Böckelmann, I
2016-11-01
Surgeons routinely work in an environment with occupational risks and hazards about which they are often uninformed. Based on the currently available scientific literature this review article describes the various hazards in the operating theater and their effects on personnel, particularly from the surgical perspective. A further aim of this article is to describe the occupational safety measures to reduce the burdens and to maintain the long-term health of personnel. Ultimately, surgeons should be equipped with the necessary knowledge for implementing hazard assessments according to the German Occupational Health and Safety Act. Surgeons are exposed to increased risks and hazards by working in awkward positions with a high risk for musculoskeletal pain and injuries. They are also commonly exposed to inhalational anesthetics, surgical smoke, radiation, noise and infectious agents. Furthermore, the mental and emotional stress associated with these activities is also high. Meaningful occupational safety measures for reduction of burdens are from a technical aspect the installation of effective air extraction systems, measures to reduce exposure to radiation and noise and the use of safer instruments to prevent needle stick injuries. Furthermore, individual occupational safety measures, such as the use of personal protective equipment (e.g. radiation protective clothing and double gloves) must be observed. The consistent implementation and also adherence to these described occupational safety measures and regulations can reduce the burden on operating theater personnel and contribute to maintaining health. Furthermore, periodic preventive healthcare controls and health checks by the company medical officer and individually initiated additional prevention measures can be a sensible augmentation to these safety measures.
2008-10-01
732) 866-2821 Hazards of Electromagnetic Radiation to Ordnance ( HERO ) Mr. Charles Denham/Rick Magrogan Naval Surface Warfare Center, Dahlgren...with a lightning strike; thus the requirements of paragraph C7.4.1 of reference (b) are met. (4) There are no electromagnetic radiation hazards to...the other hazardous material requirements of 49 CFR. This includes, but is not limited to, the packaging, electromagnetic radiation , and
Ahmadi, Mehrdad; Salehi, Bahareh; Abd-Alla, Adly M M; Babaie, Mohammad
2018-05-30
Bactrocera oleae is one of the most hazardous pests threatening olive orchards in Iran. SIT is an environment-friendly system of pest control based on releasing sterile males able to compete with wild males to mate with wild females. To determine sterile doses of radiation, pupae were irradiated to the doses of 0-160 Gy. Doses of 90-100 Gy were found optimal providing the necessary sterilization without severely impairing the competitiveness of the irradiated males in mating. Copyright © 2018 Elsevier Ltd. All rights reserved.
Space radiation hazards to Project Skylab photographic film, phase 2
NASA Technical Reports Server (NTRS)
Hill, C. W.; Neville, C. F.
1971-01-01
The results of a study of space radiation hazards to Project Skylab photographic film are presented. Radiation components include trapped protons, trapped electrons, bremsstrahlung, and galactic cosmic radiation. The shielding afforded by the Skylab cluster is taken into account with a 5000 volume element mathematical model. A preliminary survey of expected proton spectrometer data is reported.
NASA Technical Reports Server (NTRS)
1990-01-01
Scientific Instruments, Inc. has now developed a second generation, commercially available instrument to detect flames in hazardous environments, typically refineries, chemical plants and offshore drilling platforms. The Model 74000 detector incorporates a sensing circuit that detects UV radiation in a 100 degree conical field of view extending as far as 250 feet from the instrument. It operates in a bandwidth that makes it virtually 'blind' to solar radiation while affording extremely high sensitivity to ultraviolet flame detection. A 'windowing' technique accurately discriminates between background UV radiation and ultraviolet emitted from an actual flame, hence the user is assured of no false alarms. Model 7410CP is a combination controller and annunciator panel designed to monitor and control as many as 24 flame detectors. *Model 74000 is no longer being manufactured.
Reverberant Microwave Propagation
2008-10-01
HERO Hazards of Electromagnetic Radiation to Ordnance HP Hewlett Packard HWD Half-Wave Dipole IEC International Electrotechnical Commission IEE...composite panels used in new ship design; Hazards of Electromagnetic Radiation to Ordnance ( HERO ) analyses; and digital wireless system performance...Electro-Explosive Device EMC Electromagnetic Compatibility ft Foot (feet) GHz Gigahertz HERO Hazards of Electromagnetic
Changizi, Vahid; Alizadeh, Mohammad Hossein; Mousavi, Akbar
2015-01-01
CT scan and nuclear medicine exams deliver a great part of medical exposures. This study examined professional radiation hazards in CT scan and nuclear medicine workers. In a cross sectional study 30 occupationally exposed workers and 7 controls (all from personnel of a laboratory) were selected. Physical dosimetry was performed for exposed workers. Blood samples were obtained from the experimental and control groups. Three culture mediums for each one were prepared in due to routine chromosome analysis using G-banding and solid stain. There were significant increased incidence of chromatid gap (ctg) and chromatid break (ctb) with mean±SD frequencies of 3±0.84 and 3.1±1.40 per 100 cells respectively in the nuclear medicine workers versus controls with mean±SD frequencies of 1.9±0.69 and 1.3±0.84 for ctg and ctb, respectively. Chromosome gaps (chrg) were higher significantly in the nuclear medicine population (2.47±0.91) than in controls (1.4±0.9) (p< 0.05). In CT scan group the ctg and ctb were increased with a mean±SD frequency of 2.7±0.79 and 2.6±0.91 per 100 cells respectively compared with control group. The mean±SD frequencies of the chrb were 2.0±0.75 and 0.86±0.690 per 100 cells for exposed workers and control group, respectively. This study showed chromosome aberrations in peripheral lymphocytes using solid stain method are reasonable biomarker reflecting personnel radiation damage.
Evaluating optical hazards from plasma arc cutting.
Glassford, Eric; Burr, Gregory
2018-01-01
The Health Hazard Evaluation Program of the National Institute for Occupational Safety and Health evaluated a steel building materials manufacturer. The employer requested the evaluation because of concerns about optical radiation hazards from a plasma arc cutting system and the need to clarify eye protection requirements for plasma operators, other employees, and visitors. The strength of the ultraviolet radiation, visible radiation (light), and infrared radiation generated by the plasma arc cutter was measured at various distances from the source and at different operating amperages. Investigators also observed employees performing the plasma arc cutting. Optical radiation above safe levels for the unprotected eyes in the ultraviolet-C, ultraviolet-B, and visible light ranges were found during plasma arc cutting. In contrast, infrared and ultraviolet-A radiation levels during plasma arc cutting were similar to background levels. The highest non-ionizing radiation exposures occurred when no welding curtains were used. A plasma arc welding curtain in place did not eliminate optical radiation hazards to the plasma arc operator or to nearby employees. In most instances, the measured intensities for visible light, UV-C, and UV-B resulted in welding shade lens numbers that were lower than those stipulated in the OSHA Filter Lenses for Protection Against Radiant Energy table in 29 CFR 1910.133(a)(5). [1] Investigators recommended using a welding curtain that enclosed the plasma arc, posting optical radiation warning signs in the plasma arc cutter area, installing audible or visual warning cues when the plasma arc cutter was operating, and using welding shades that covered the plasma arc cutter operator's face to protect skin from ultraviolet radiation hazards.
Thyroid cancer following scalp irradiation. [X radiation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Modan, B.; Ron, E.; Werner, A.
1977-05-25
A sixfold increase in the risk of thyroid cancer was observed among 10,902 persons irradiated for scalp tinea in childhood as compared to two matched control groups. The dosimetry studies demonstrated that the original mean dose given to the thyroid was less than 9 rads, yielding a risk of 6.3/10/sup 6//year. This carcinogenic effect of low-level radiation must be considered in the planning of safety measures against potential public health hazards.
Genotoxicity and carcinogenicity of the light emitted by artificial illumination systems.
De Flora, Silvio
2013-03-01
The light delivered by artificial illumination systems, and in particular by halogen quartz bulbs, contains UVA, UVB, and UVC radiation, is genotoxic to both bacterial and human cells and is potently carcinogenic to hairless mice. Since IARC has classified UV radiation in Group 1, any source of UV light poses a carcinogenic hazard to humans. Suitable regulations would be needed in order to control the safety of the light emitted by artificial light sources.
NV/YMP radiological control manual, Revision 2
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gile, A.L.
The Nevada Test Site (NTS) and the adjacent Yucca Mountain Project (YMP) are located in Nye County, Nevada. The NTS has been the primary location for testing nuclear explosives in the continental US since 1951. Current activities include operating low-level radioactive and mixed waste disposal facilities for US defense-generated waste, assembly/disassembly of special experiments, surface cleanup and site characterization of contaminated land areas, and non-nuclear test operations such as controlled spills of hazardous materials at the hazardous Materials (HAZMAT) Spill Center (HSC). Currently, the major potential for occupational radiation exposure is associated with the burial of low-level nuclear waste andmore » the handling of radioactive sources. Planned future remediation of contaminated land areas may also result in radiological exposures. The NV/YMP Radiological Control Manual, Revision 2, represents DOE-accepted guidelines and best practices for implementing Nevada Test Site and Yucca Mountain Project Radiation Protection Programs in accordance with the requirements of Title 10 Code of Federal Regulations Part 835, Occupational Radiation Protection. These programs provide protection for approximately 3,000 employees and visitors annually and include coverage for the on-site activities for both personnel and the environment. The personnel protection effort includes a DOE Laboratory Accreditation Program accredited dosimetry and personnel bioassay programs including in-vivo counting, routine workplace air sampling, personnel monitoring, and programmatic and job-specific As Low as Reasonably Achievable considerations.« less
Solar cosmic rays as a specific source of radiation risk during piloted space flight.
Petrov, V M
2004-01-01
Solar cosmic rays present one of several radiation sources that are unique to space flight. Under ground conditions the exposure to individuals has a controlled form and radiation risk occurs as stochastic radiobiological effects. Existence of solar cosmic rays in space leads to a stochastic mode of radiation environment as a result of which any radiobiological consequences of exposure to solar cosmic rays during the flight will be probabilistic values. In this case, the hazard of deterministic effects should also be expressed in radiation risk values. The main deterministic effect under space conditions is radiation sickness. The best dosimetric functional for its analysis is the blood forming organs dose equivalent but not an effective dose. In addition, the repair processes in red bone marrow affect strongly on the manifestation of this pathology and they must be taken into account for radiation risk assessment. A method for taking into account the mentioned above peculiarities for the solar cosmic rays radiation risk assessment during the interplanetary flights is given in the report. It is shown that radiation risk of deterministic effects defined, as the death probability caused by radiation sickness due to acute solar cosmic rays exposure, can be comparable to risk of stochastic effects. Its value decreases strongly because of the fractional mode of exposure during the orbital movement of the spacecraft. On the contrary, during the interplanetary flight, radiation risk of deterministic effects increases significantly because of the residual component of the blood forming organs dose from previous solar proton events. The noted quality of radiation responses must be taken into account for estimating radiation hazard in space. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.
Astronaut Exposures to Ionizing Radiation in a Lightly-Shielded Spacesuit
NASA Technical Reports Server (NTRS)
Wilson, J. W.; Simonsen, L. C.; Shinn, J. L.; Kim, M.-H. Y.; Cucinotta, F. A.; Badavi, F. F.; Atwell, W.
1999-01-01
The normal working and living areas of the astronauts are designed to provide an acceptable level of protection against the hazards of ionizing radiation of the space environment. Still there are occasions when they must don a spacesuit designed mainly for environmental control and mobility and leave the confines of their better-protected domain. This is especially true for deep space exploration. The impact of spacesuit construction on the exposure of critical astronaut organs will be examined in the ionizing radiation environments of free space, the lunar surface and the Martian surface. The computerized anatomical male model is used to evaluate astronaut self-shielding factors and to determine space radiation exposures to critical radiosensitive human organs.
System and Network Security Acronyms and Abbreviations
2009-09-01
hazards of electromagnetic radiation to fuel HERO hazards of electromagnetic radiation to ordnance HERP hazards of electromagnetic ...ABSTRACT unclassified c. THIS PAGE unclassified Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 System and Network Security Acronyms...authentication and key management ALG application layer gateway ANSI American National Standards Institute AP access point API application
2015-02-25
required. For example, RF transmitting equipment is tested for Hazards of Electromagnetic Radiation to Personnel ( HERP ) at EPG’s Electromagnetic...Environmental Effects EPG U.S. Army Electronic Proving Ground GFCI ground fault circuit interrupter GOTS Government off-the-shelf HERP
Ocular hazards of industrial spot welding.
Chou, B R; Cullen, A P
1996-06-01
Any welding process is perceived to be a radiation hazard to the eye. Site visits were made to an automotive assembly plant to assess the levels of optical radiation and other hazards on the production line. Measurements were taken with a scanning spectro-radiometer and optical power and energy meters at operating working distances at spot welding stations where nonrobotic procedures were performed. Ultraviolet (UV) irradiance levels produced while spot welding with electrodes operating at 10 to 15 kA and 10 to 20 V were several orders of magnitude below recommended safety limits for industrial exposure. Flashes were rich in visible light and infrared (IR) radiation, but not at hazardous levels. The principal hazards in manual spot welding with high-current electrodes are high-speed droplets of molten metal produced by the process. These are easily defended against by wraparound polycarbonate eye shields.
An Underappreciated Radiation Hazard from High Voltage Electrodes in Vacuum.
West, Adam D; Lasner, Zack; DeMille, David; West, Elizabeth P; Panda, Cristian D; Doyle, John M; Gabrielse, Gerald; Kryskow, Adam; Mitchell, Corinne
2017-01-01
The use of high voltage (HV) electrodes in vacuum is commonplace in physics laboratories. In such systems, it has long been known that electron emission from an HV cathode can lead to bremsstrahlung x rays; indeed, this is the basic principle behind the operation of standard x-ray sources. However, in laboratory setups where x-ray production is not the goal and no electron source is deliberately introduced, field-emitted electrons accelerated by HV can produce x rays as an unintended hazardous byproduct. Both the level of hazard and the safe operating regimes for HV vacuum electrode systems are not widely appreciated, at least in university laboratories. A reinforced awareness of the radiation hazards associated with vacuum HV setups would be beneficial. The authors present a case study of a HV vacuum electrode device operated in a university atomic physics laboratory. They describe the characterization of the observed x-ray radiation, its relation to the observed leakage current in the device, the steps taken to contain and mitigate the radiation hazard, and suggested safety guidelines.
Pelvis Ewing sarcoma: Local control and survival in the modern era.
Ahmed, Safia K; Robinson, Steven I; Arndt, Carola A S; Petersen, Ivy A; Haddock, Michael G; Rose, Peter S; Issa Laack, Nadia N
2017-09-01
Local control for Ewing sarcoma (ES) has improved in modern studies. However, it is unclear if these gains have also been achieved for pelvis tumors. The purpose of this study is to evaluate local control and survival in pelvis ES patients treated in the modern era. All pelvis ES patients diagnosed from 1990 to 2012 and seen at Mayo Clinic were identified. Factors relevant to survival and local control were analyzed. The cohort consisted of 48 patients. Fifty-two percent had metastatic disease at diagnosis. The 5-year overall survival and event-free survival was 73% and 65%, respectively, for localized disease. The 5-year cumulative incidence of local recurrence was 19%, with a 26% incidence for radiation, 13% for surgery, and 0% for surgery + radiation (P = 0.54). All local failures occurred in-field. Sacral involvement by tumor trended toward a higher incidence of local recurrence (hazard ratio 3.06, P = 0.09). Patients treated with definitive radiation doses ≥5,600 cGy had a lower incidence of local recurrence (17% vs. 28%, P = 0.61). Our study demonstrates excellent survival for localized tumors in the modern era. Anatomical localization within the pelvis likely correlates with outcomes. Local control remains problematic, especially for patients treated with definitive radiation. Though statistically not significant, surgery + radiation and definitive radiation dose ≥5,600 cGy were associated with the lowest incidence of local failure, suggesting treatment intensification may improve local control for pelvis ES. © 2017 Wiley Periodicals, Inc.
Demonstration of Electro-Osmotic Pulse Technology in Earth-Covered Magazines at Fort A.P. Hill, VA
2009-08-01
Electromagnetic Radiation to Ordnance ( HERO ) Evaluation Tests were conducted on magazines to detect any radio frequency (RF) emissions produced and to...measure electromagnetic (EM) radiation from the anodes installed in the magazines. The detailed results of a HERO ( Hazards of Electromagnetic ...reinforcement steel ........................................................... 14 3.3.6 Testing for electromagnetic radiation hazards
Gralewicz, Grzegorz; Owczarek, Grzegorz
2016-09-01
The paper analyses the selected optical parameters of protective optic filters used for protection of the eyes against hazardous radiation within the visible (VIS) and near infrared (NIR) spectrum range. The indexes characterizing transmission and reflection of optic radiation incident on the filter are compared. As it follows from the completed analysis, the newly developed interference filters provide more effective blocking of infrared radiation in comparison with the currently used protective filters.
NASA Technical Reports Server (NTRS)
Davis, V. Leon; Nordeen, Ross
1988-01-01
A laboratory for developing robotics technology for hazardous and repetitive Shuttle and payload processing activities is discussed. An overview of the computer hardware and software responsible for integrating the laboratory systems is given. The center's anthropomorphic robot is placed on a track allowing it to be moved to different stations. Various aspects of the laboratory equipment are described, including industrial robot arm control, smart systems integration, the supervisory computer, programmable process controller, real-time tracking controller, image processing hardware, and control display graphics. Topics of research include: automated loading and unloading of hypergolics for space vehicles and payloads; the use of mobile robotics for security, fire fighting, and hazardous spill operations; nondestructive testing for SRB joint and seal verification; Shuttle Orbiter radiator damage inspection; and Orbiter contour measurements. The possibility of expanding the laboratory in the future is examined.
Action levels for airborne uranium in the workplace: chemical and radiological assessments.
Leggett, R W; Meck, R A
2018-06-01
A method is described for deriving two levels of action-an investigation level (IL) and an immediate action level (IAL)-for different forms and mixtures of the natural uranium (U) isotopes 234 U, 235 U, and 238 U in air in the workplace. An IL indicates the need to confirm the validity of moderately elevated measurements of airborne U and adequacy of confinement controls and determine whether work limitations are appropriate. An IAL indicates that safeguards should be put into place immediately, including removal of workers from further exposure until conditions are acceptable. Derivations of ILs and IALs are based on latest radiation protection guidance, information on chemical toxicity of U, and biokinetic models for U. An action level (IL or IAL) is the more restrictive of two derived values, the action level based on U as a chemical hazard and the action level based on U as a radiation hazard.
Cassini at Saturn Proximal Orbits - Attitude Control Challenges
NASA Technical Reports Server (NTRS)
Burk, Thomas A.
2013-01-01
The Cassini mission at Saturn will come to an end in the spring and summer of 2017 with a series of 22 orbits that will dip inside the rings of Saturn. These are called proximal orbits and will conclude with spacecraft disposal into the atmosphere of the ringed world on September 15, 2017. These unique orbits that cross the ring plane only a few thousand kilometers above the cloud tops of the planet present new attitude control challenges for the Cassini operations team. Crossing the ring plane so close to the inner edge of the rings means that the Cassini orientation during the crossing will be tailored to protect the sensitive electronics bus of the spacecraft. This orientation will put the sun sensors at some extra risk so this paper discusses how the team prepares for dust hazards. Periapsis is so close to the planet that spacecraft controllability with RCS thrusters needs to be evaluated because of the predicted atmospheric torque near closest approach to Saturn. Radiation during the ring plane crossings will likely trigger single event transients in some attitude control sensors. This paper discusses how the attitude control team deals with radiation hazards. The angular size and unique geometry of the rings and Saturn near periapsis means that star identification will be interrupted and this paper discusses how the safe mode attitude is selected to best deal with these large bright bodies during the proximal orbits.
A brief review of intermediate controlled nuclear syntheses (ICNS) without harmful radiations
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lanjewar, R. B.
Hadronic mechanics gave birth to new magnecular fuels. The present day demand is of clean energy source that is cheap and abundant. Clean energy can be obtained by harnessing renewable energy sources like solar, wind etc. Nuclear energy conventionally produced by fission reactions emits hazardous radiation and radioactive waste. The requirements of clean and safe energy gets fulfilled by novel fuel that achieved by elevating the traditional quantum mechanics to hadronic mechanics and to hadronic chemistry. In the present paper, a comprehensive review on both the theoretical and experimental aspect of the Intermediate Controlled Nuclear Synthesis (ICNS) as developed bymore » Italian American Scientist Professor R. M. Santilli.« less
Natural radiation hazards on the manned Mars mission
NASA Technical Reports Server (NTRS)
Letaw, John R.; Silberberg, Rein; Tsao, C. H.
1986-01-01
The hazards of the natural radiation environment (cosmic rays and solar energetic particles) on a manned mission to Mars are considered. These hazards are addressed in three different settings: the flight to Mars where the astronauts are shielded only by the spacecraft; on the surface of Mars under an atmosphere of about 10 g/sq cm carbon dioxide; and under the surface of Mars where additional shielding would result.
Radiation Hazards and Countermeasures for Human Space Flight
NASA Technical Reports Server (NTRS)
Adams, James
2004-01-01
The protection of astronauts from the hazards of ionizing radiation in space is a moral and legal obligation of NASA. If there are to be manned deep-space missions, means must be found to provide this protection. There are two parts to providing this protection: understanding the effects of space radiation on humans so that radiation exposure limits can be established; and developing countermeasures so that exposures can be kept below these limits. This talk will cover both parts of this problem.
DOT National Transportation Integrated Search
1997-07-01
This report provides estimates of the numbers of persons injured as a result of : hazards involving four specific motor vehicle components: radiators, batteries, : power windows, and power roofs. The injury estimates are based upon data from : the Co...
A decade of changes in radiation protection.
Moulder, J E
1992-04-01
Although radiation protection standards have changed remarkably little over the past decade, there have been changes in our understanding of radiation hazards that may affect the practice of radiation medicine over the next decade. With recognition of indoor radon exposure has come a new focus for public health concerns, because it is now clear that radon rather than medical exposure is the largest controllable source of radiation exposure to the general public. Continued follow-up of irradiated populations has led to an increase in our estimate of the cancer risk for high-dose exposures; this increased risk estimate is, in turn, leading to decreases in radiation exposure limits. Although our concern about the carcinogenic risk for radiation exposure has increased, our concern about genetic consequences has decreased, because no genetic effects have yet been observed in the offspring of atomic bomb survivors. Studies of atomic bomb survivors have also led to a change in the focus of concern over prenatal radiation exposure; the principle risk now appears to be mental retardation rather than childhood cancer.
Submerged RadBall® deployments in Hanford Site hot cells containing 137CsCl capsules.
Farfán, Eduardo B; Coleman, J Rusty; Stanley, Steven; Adamovics, John; Oldham, Mark; Thomas, Andrew
2012-07-01
The overall objective of this study was to demonstrate that a new technology, known as RadBall®, could locate submerged radiological hazards. RadBall® is a novel, passive, radiation detection device that provides a 3-D visualization of radiation from areas where measurements have not been previously possible due to lack of access or extremely high radiation doses. This technology has been under development during recent years, and all of its previous tests have included dry deployments. This study involved, for the first time, underwater RadBall® deployments in hot cells containing 137CsCl capsules at the U.S. Department of Energy's Hanford Site. RadBall® can be used to characterize a contaminated room, hot cell, or glovebox by providing the locations of the radiation sources and hazards, identifying the radionuclides present within the cell, and determining the radiation sources' strength (e.g., intensities or dose rates). These parameters have been previously determined for dry deployments; however, only the location of radiation sources and hazards can be determined for an underwater RadBall® deployment. The results from this study include 3-D images representing the location of the radiation sources within the Hanford Site cells. Due to RadBall®'s unique deployability and non-electrical nature, this technology shows significant promise for future characterization of radiation hazards prior to and during the decommissioning of contaminated nuclear facilities.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shinohara, Eric T.; Mitra, Nandita; Guo Mengye
Purpose: Intrahepatic cholangiocarcinomas (IHC) are rare tumors for which large randomized studies regarding the use of radiation are not available. The purpose of this study was to examine the role of adjuvant and definitive radiation therapy in the treatment of IHC in a large group of patients. Methods and Materials: This is a retrospective analysis of 3,839 patients with IHC collected from the Surveillance, Epidemiology, and End Results (SEER) database. The primary endpoint was overall survival (OS). Results: Patients received either surgery alone (25%), radiation therapy alone (10%), surgery and adjuvant radiation therapy (7%) or no treatment (58%). The medianmore » age of the patient population was 73 years (range, 22-102 years); 52% of patients were male and 81% were Caucasian. Median OS was 11 (95% confidence interval [CI], 9-13), 6 (95% CI, 5-6), 7 (95% CI, 6-8), and 3 months for surgery and adjuvant radiation therapy, sugery alone, radiation therapy alone, and no treatment, respectively. The OS was significantly different between surgery alone and surgery and adjuvant radiation therapy (p = 0.014) and radiation therapy alone and no treatment (p < 0.0001). Use of surgery and adjuvant radiation therapy conferred the greatest benefit on OS (HR = 0.40; 95% CI, 0.34-0.47), followed by surgery alone (hazard ratio [HR], 0.49; 95% CI, 0.44-0.54) and radiation therapy alone (HR, 0.68; 95% CI, 0.59-0.77) compared with no treatment, on multivariate analysis. Propensity score adjusted hazard ratios (controlling for age, race/ethnicity, stage, and year of diagnosis) were also significant (surgery and adjuvant radiation therapy vs. surgery alone (HR, 0.82; 95% CI, 0.70-0.96); radiation therapy alone vs. no treatment (HR, 0.67; 95% CI, 0.58-0.76)). Conclusions: The study results suggest that adjuvant and definitive radiation treatment prolong survival, although cure rates remain low. Future studies should evaluate the addition of chemotherapy and biologics to the treatment of IHC.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tang, A; Samost, A; Viswanathan, A
Purpose: To investigate the hazards in cervical-cancer HDR brachytherapy using a novel hazard-analysis technique, System Theoretic Process Analysis (STPA). The applicability and benefit of STPA to the field of radiation oncology is demonstrated. Methods: We analyzed the tandem and ring HDR procedure through observations, discussions with physicists and physicians, and the use of a previously developed process map. Controllers and their respective control actions were identified and arranged into a hierarchical control model of the system, modeling the workflow from applicator insertion through initiating treatment delivery. We then used the STPA process to identify potentially unsafe control actions. Scenarios weremore » then generated from the identified unsafe control actions and used to develop recommendations for system safety constraints. Results: 10 controllers were identified and included in the final model. From these controllers 32 potentially unsafe control actions were identified, leading to more than 120 potential accident scenarios, including both clinical errors (e.g., using outdated imaging studies for planning), and managerial-based incidents (e.g., unsafe equipment, budget, or staffing decisions). Constraints identified from those scenarios include common themes, such as the need for appropriate feedback to give the controllers an adequate mental model to maintain safe boundaries of operations. As an example, one finding was that the likelihood of the potential accident scenario of the applicator breaking during insertion might be reduced by establishing a feedback loop of equipment-usage metrics and equipment-failure reports to the management controller. Conclusion: The utility of STPA in analyzing system hazards in a clinical brachytherapy system was demonstrated. This technique, rooted in system theory, identified scenarios both technical/clinical and managerial in nature. These results suggest that STPA can be successfully used to analyze safety in brachytherapy and may prove to be an alternative to other hazard analysis techniques.« less
Ground-motion signature of dynamic ruptures on rough faults
NASA Astrophysics Data System (ADS)
Mai, P. Martin; Galis, Martin; Thingbaijam, Kiran K. S.; Vyas, Jagdish C.
2016-04-01
Natural earthquakes occur on faults characterized by large-scale segmentation and small-scale roughness. This multi-scale geometrical complexity controls the dynamic rupture process, and hence strongly affects the radiated seismic waves and near-field shaking. For a fault system with given segmentation, the question arises what are the conditions for producing large-magnitude multi-segment ruptures, as opposed to smaller single-segment events. Similarly, for variable degrees of roughness, ruptures may be arrested prematurely or may break the entire fault. In addition, fault roughness induces rupture incoherence that determines the level of high-frequency radiation. Using HPC-enabled dynamic-rupture simulations, we generate physically self-consistent rough-fault earthquake scenarios (M~6.8) and their associated near-source seismic radiation. Because these computations are too expensive to be conducted routinely for simulation-based seismic hazard assessment, we thrive to develop an effective pseudo-dynamic source characterization that produces (almost) the same ground-motion characteristics. Therefore, we examine how variable degrees of fault roughness affect rupture properties and the seismic wavefield, and develop a planar-fault kinematic source representation that emulates the observed dynamic behaviour. We propose an effective workflow for improved pseudo-dynamic source modelling that incorporates rough-fault effects and its associated high-frequency radiation in broadband ground-motion computation for simulation-based seismic hazard assessment.
Morton, Lindsay M; Sampson, Joshua N; Armstrong, Gregory T; Chen, Ting-Huei; Hudson, Melissa M; Karlins, Eric; Dagnall, Casey L; Li, Shengchao Alfred; Wilson, Carmen L; Srivastava, Deo Kumar; Liu, Wei; Kang, Guolian; Oeffinger, Kevin C; Henderson, Tara O; Moskowitz, Chaya S; Gibson, Todd M; Merino, Diana M; Wong, Jeannette R; Hammond, Sue; Neglia, Joseph P; Turcotte, Lucie M; Miller, Jeremy; Bowen, Laura; Wheeler, William A; Leisenring, Wendy M; Whitton, John A; Burdette, Laurie; Chung, Charles; Hicks, Belynda D; Jones, Kristine; Machiela, Mitchell J; Vogt, Aurelie; Wang, Zhaoming; Yeager, Meredith; Neale, Geoffrey; Lear, Matthew; Strong, Louise C; Yasui, Yutaka; Stovall, Marilyn; Weathers, Rita E; Smith, Susan A; Howell, Rebecca; Davies, Stella M; Radloff, Gretchen A; Onel, Kenan; Berrington de González, Amy; Inskip, Peter D; Rajaraman, Preetha; Fraumeni, Joseph F; Bhatia, Smita; Chanock, Stephen J; Tucker, Margaret A; Robison, Leslie L
2017-11-01
Childhood cancer survivors treated with chest-directed radiotherapy have substantially elevated risk for developing breast cancer. Although genetic susceptibility to breast cancer in the general population is well studied, large-scale evaluation of breast cancer susceptibility after chest-directed radiotherapy for childhood cancer is lacking. We conducted a genome-wide association study of breast cancer in female survivors of childhood cancer, pooling two cohorts with detailed treatment data and systematic, long-term follow-up: the Childhood Cancer Survivor Study and St. Jude Lifetime Cohort. The study population comprised 207 survivors who developed breast cancer and 2774 who had not developed any subsequent neoplasm as of last follow-up. Genotyping and subsequent imputation yielded 16 958 466 high-quality variants for analysis. We tested associations in the overall population and in subgroups stratified by receipt of lower than 10 and 10 or higher gray breast radiation exposure. We report P values and pooled per-allele risk estimates from Cox proportional hazards regression models. All statistical tests were two-sided. Among survivors who received 10 or higher gray breast radiation exposure, a locus on 1q41 was associated with subsequent breast cancer risk (rs4342822, nearest gene PROX1 , risk allele frequency in control subjects [RAF controls ] = 0.46, hazard ratio = 1.92, 95% confidence interval = 1.49 to 2.44, P = 7.09 × 10 -9 ). Two rare variants also showed potentially promising associations (breast radiation ≥10 gray: rs74949440, 11q23, TAGLN , RAF controls = 0.02, P = 5.84 × 10 -8 ; <10 gray: rs17020562, 1q32.3, RPS6KC1 , RAF controls = 0.0005, P = 6.68 × 10 -8 ). Associations were restricted to these dose subgroups, with consistent findings in the two survivor cohorts. Our study provides strong evidence that germline genetics outside high-risk syndromes could modify the effect of radiation exposure on breast cancer risk after childhood cancer. Published by Oxford University Press 2017. This work is written by US Government employees and is in the public domain in the US.
31. SECTIONS AND DETAILS OF ARVFS FACILITY, INCLUDING RADIATION HAZARD ...
31. SECTIONS AND DETAILS OF ARVFS FACILITY, INCLUDING RADIATION HAZARD SIGN, WOOD RETAINING WALL, TANK COVER, AND DRAIN BOX. F.C. TORKELSON DRAWING NUMBER 842-ARVFS-701-3. INEL INDEX CODE NUMBER: 075 0701 851 151972. - Idaho National Engineering Laboratory, Advanced Reentry Vehicle Fusing System, Scoville, Butte County, ID
THE HAZARD OF CORPUSCULAR SOLAR RADIATION TO MANNED SPACEFLIGHT
DOE Office of Scientific and Technical Information (OSTI.GOV)
Waddington, C.J.
BS>The presently available data on the storms'' of solar particles are used to compute the radiation dose that would be received by astronauts shielded by different thicknesses of material. It is shown that at least some of these storms represent a severe hazard to successful manned spaceflights. (auth)
Exposure assessment of aluminum arc welding radiation.
Peng, Chiung-yu; Lan, Cheng-hang; Juang, Yow-jer; Tsao, Ta-ho; Dai, Yu-tung; Liu, Hung-hsin; Chen, Chiou-jong
2007-10-01
The purpose of this study is to evaluate the non-ionizing radiation (NIR) exposure, especially optical radiation levels, and potential health hazard from aluminum arc welding processes based on the American Conference of Governmental Industrial Hygienists (ACGIH) method. The irradiance from the optical radiation emissions can be calculated with various biological effective parameters [i.e., S(lambda), B(lambda), R(lambda)] for NIR hazard assessments. The aluminum arc welding processing scatters bright light with NIR emission including ultraviolet radiation (UVR), visible, and infrared spectra. The UVR effective irradiance (Eeff) has a mean value of 1,100 microW cm at 100 cm distance from the arc spot. The maximum allowance time (tmax) is 2.79 s according to the ACGIH guideline. Blue-light hazard effective irradiance (EBlue) has a mean value of 1840 microW cm (300-700 nm) at 100 cm with a tmax of 5.45 s exposure allowance. Retinal thermal hazard effective calculation shows mean values of 320 mW cm(-2) sr(-1) and 25.4 mW (cm-2) (380-875 nm) for LRetina (spectral radiance) and ERetina (spectral irradiance), respectively. From this study, the NIR measurement from welding optical radiation emissions has been established to evaluate separate types of hazards to the eye and skin simultaneously. The NIR exposure assessment can be applied to other optical emissions from industrial sources. The data from welding assessment strongly suggest employees involved in aluminum welding processing must be fitted with appropriate personal protection devices such as masks and gloves to prevent serious injuries of the skin and eyes upon intense optical exposure.
Radio-Adaptive Responses of Mouse Myocardiocytes
NASA Technical Reports Server (NTRS)
Seawright, John W.; Westby, Christian M.
2011-01-01
One of the most significant occupational hazards to an astronaut is the frequent exposure to radiation. Commonly associated with increased risk for cancer related morbidity and mortality, radiation is also known to increase the risk for cardiovascular related disorders including: pericarditis, hypertension, and heart failure. It is believed that these radiation-induced disorders are a result of abnormal tissue remodeling. It is unknown whether radiation exposure promotes remodeling through fibrotic changes alone or in combination with programmed cell death. Furthermore, it is not known whether it is possible to mitigate the hazardous effects of radiation exposure. As such, we assessed the expression and mechanisms of radiation-induced tissue remodeling and potential radio-adaptive responses of p53-mediated apoptosis and fibrosis pathways along with markers for oxidative stress and inflammation in mice myocardium. 7 week old, male, C57Bl/6 mice were exposed to 6Gy (H) or 5cGy followed 24hr later with 6Gy (LH) Cs-137 gamma radiation. Mice were sacrificed and their hearts extirpated 4, 24, or 72hr after final irradiation. Real Time - Polymerase Chain Reaction was used to evaluate target genes. Pro-apoptotic genes Bad and Bax, pro-cell survival genes Bcl2 and Bcl2l2, fibrosis gene Vegfa, and oxidative stress genes Sod2 and GPx4 showed a reduced fold regulation change (Bad,-6.18; Bax,-6.94; Bcl2,-5.09; Bcl2l2,-4.03; Vegfa, -11.84; Sod2,-5.97; GPx4*,-28.72; * = Bonferroni adjusted p-value . 0.003) 4hr after H, but not after 4hr LH when compared to control. Other p53-mediated apoptosis genes Casp3, Casp9, Trp53, and Myc exhibited down-regulation but did not achieve a notable level of significance 4hr after H. 24hr after H, genetic down-regulation was no longer present compared to 24hr control. These data suggest a general reduction in genetic expression 4hrs after a high dose of gamma radiation. However, pre-exposure to 5cGy gamma radiation appears to facilitate a radio-adaptive response that mitigates the reduction in genetic expression associated with single high-dose gamma radiation exposure. This radio-adaptive response may serve as a potential countermeasure to radiation-induced myocardial remodeling and preserve the cardiovascular health of astronauts; thus, reducing the risks of human space exploration.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tseng, Yolanda D., E-mail: ydt2@uw.edu; Chen, Yu-Hui; Catalano, Paul J.
Purpose: To evaluate the response rate (RR) and time to local recurrence (TTLR) among patients who received salvage radiation therapy for relapsed or refractory aggressive non-Hodgkin lymphoma (NHL) and investigate whether RR and TTLR differed according to disease characteristics. Methods and Materials: A retrospective review was performed for all patients who completed a course of salvage radiation therapy between January 2001 and May 2011 at Brigham and Women's Hospital/Dana-Farber Cancer Institute. Separate analyses were conducted for patients treated with palliative and curative intent. Predictors of RR for each subgroup were assessed using a generalized estimating equation model. For patients treatedmore » with curative intent, local control (LC) and progression-free survival were estimated with the Kaplan-Meier method; predictors for TTLR were evaluated using a Cox proportional hazards regression model. Results: Salvage radiation therapy was used to treat 110 patients to 121 sites (76 curative, 45 palliative). Salvage radiation therapy was given as part of consolidation in 18% of patients treated with curative intent. Median dose was 37.8 Gy, with 58% and 36% of curative and palliative patients, respectively, receiving 39.6 Gy or higher. The RR was high (86% curative, 84% palliative). With a median follow-up of 4.8 years among living patients, 5-year LC and progression-free survival for curative patients were 66% and 34%, respectively. Refractory disease (hazard ratio 3.3; P=.024) and lack of response to initial chemotherapy (hazard ratio 4.3; P=.007) but not dose (P=.93) were associated with shorter TTLR. Despite doses of 39.6 Gy or higher, 2-year LC was only 61% for definitive patients with refractory disease or disease that did not respond to initial chemotherapy. Conclusions: Relapsed or refractory aggressive NHL is responsive to salvage radiation therapy, and durable LC can be achieved in some cases. However, refractory disease is associated with a shorter TTLR, suggesting that radiation dose escalation, addition of radiosensitizers, or a combination of both may be indicated in these patients.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Basu, Partha, E-mail: BasuP@iarc.fr; Jenson, Alfred Bennett; Majhi, Tapas
Purpose: Because a combination of retinoic acid, interferon-alpha, and radiation therapy demonstrated synergistic action and effectiveness to treat advanced cervical cancers in earlier studies, we designed this randomized phase 2 open-label trial to assess efficacy and safety of interferon alpha-2b (IFN) and 13-cis-retinoic acid (RA) administered concomitantly with radiation therapy (IFN-RA-radiation) to treat stage III cervical cancer. Methods and Materials: Stage III cervical cancer patients were randomized to study and control groups in a 1:1 ratio. All patients were treated with radiation therapy; study arm patients received IFN (3 × 10{sup 6} IU subcutaneously) 3 times a week for 4 weeks and dailymore » RA (40 mg orally) for 30 days starting on day 1 of radiation, whereas control arm patients received weekly cisplatinum (40 mg/m{sup 2}) for 5 weeks during radiation. Patients were followed for 3 years. The primary endpoint was overall survival at 3 years. Results: Patients in the study (n=104) and control (n=105) groups were comparable for clinicopathological characteristics, radiation therapy–related variables and treatment response. Proportions of disease-free patients in the study and control groups were 38.5% and 44.8%, respectively, after median follow-up of 29.2 months. Hazard ratios were 0.67 (95% confidence interval [CI]: 0.44-1.01) and 0.69 (95% CI: 0.44-1.06) for overall and disease-fee survival, respectively, comparing the study group to control, and demonstrated an inferior outcome with RA-IFN-radiation, although differences were statistically nonsignificant. Kaplan-Meier curves of disease-free and overall survival probabilities also showed inferior survival in the study group compared to those in the control. Acute toxicities of chemoradiation were significantly higher with 2 acute toxicity-related deaths. Conclusions: Treatment with RA-IFN-radiation did not demonstrate survival advantage over chemoradiation despite being less toxic. The trends predicted an inferior outcome with the RA-IFN combination.« less
Natural radiation and its hazard in copper ore mines in Poland
NASA Astrophysics Data System (ADS)
Chau, Nguyen; Jodłowski, Paweł; Kalita, Stefan; Olko, Paweł; Chruściel, Edward; Maksymowicz, Adam; Waligórski, Michał; Bilski, Paweł; Budzanowski, Maciej
2008-06-01
The doses of gamma radiation, concentrations of radium isotopes in water and sediments, radon concentration and concentration of alpha potential energy of radon decay products in the copper ore mine and in the mining region in the vicinity of Lubin town in Poland are presented. These data served as a basis for the assessment of radiological hazard to the mine workers and general public. The results of this assessment indicate that radiological hazard in the region does not differ substantially from typical values associated with natural radiation background. The calculated average annual effective dose for copper miners is 1.48 mSv. In general, copper ore mines can be regarded as radiologically safe workplaces.
Atmospheric reentry of the in-core thermionic SP-100 reactor system
NASA Technical Reports Server (NTRS)
Stamatelatos, M. G.; Barsell, A. W.; Harris, P. A.; Francisco, J.
1987-01-01
Presumed end-of-life atmospheric reentry of the GA SP-100 system was studied to assess dispersal feasibility and associated hazards. Reentry was studied by sequential use of an orbital trajectory and a heat analysis computer program. Two heating models were used. The first model assumed a thermal equilibrium condition between the stagnation point aerodynamic heating and the radiative cooling of the skin material surface. The second model allowed for infinite conductivity of the skin material. Four reentering configurations were studied representing stages of increased SP-100 breakup: (1) radiator, shield and reactor, (2) shield and reactor, (3) reactor with control drums, and (4) reactor without control drums. Each reentering configuration was started from a circular orbit at 116 km having an inertial velocity near Mach 25. The assumed failing criterion was the attainment of melting temperature of a critical system component. The reentry analysis revealed breakup of the vessel in the neighborhood of 61 km altitude and scattering of the fuel elements. Subsequent breakup of the fuel elements was not predicted. Oxidation of the niobium skin material was calculated to cause an increase in surface temperature of less than ten percent. The concept of thermite analogs for enhancing reactor reentry dispersal was assessed and found to be feasible in principle. A conservative worst-case hazards analysis was performed for radioactive and nonradioactive toxic SP-100 materials assumed to be dispersed during end-of-life reentry. The hazards associated with this phase of the SP-100 mission were calculated to be insignificant.
Ravisankar, R; Vanasundari, K; Suganya, M; Raghu, Y; Rajalakshmi, A; Chandrasekaran, A; Sivakumar, S; Chandramohan, J; Vijayagopal, P; Venkatraman, B
2014-02-01
Using γ spectrometry, the concentration of the naturally occurring radionuclides (226)Ra, (232)Th and (40)K has been measured in soil, sand, cement, clay and bricks, which are used as building materials in Tiruvannamalai, Tamilnadu, India. The radium equivalent activity (Raeq), the criterion formula (CF), indoor gamma absorbed dose rate (DR), annual effective dose (HR), activity utilization index (AUI), alpha index (Iα), gamma index (Iγ), external radiation hazard index (Hex), internal radiation hazard index (Hin), representative level index (RLI), excess lifetime cancer risk (ELCR) and annual gonadal dose equivalent (AGDE) associated with the natural radionuclides are calculated to assess the radiation hazard of the natural radioactivity in the building materials. From the analysis, it is found that these materials used for the construction of dwellings are safe for the inhabitants. The radiological data were processed using multivariate statistical methods to determine the similarities and correlation among the various samples. The frequency distributions for all radionuclides were analyzed. The data set consisted of 15 measured variables. The Pearson correlation coefficient reveals that the (226)Ra distribution in building materials is controlled by the variation of the (40)K concentration. Principal component analysis (PCA) yields a two-component representation of the acquired data from the building materials in Tiruvannamalai, wherein 94.9% of the total variance is explained. The resulting dendrogram of hierarchical cluster analysis (HCA) classified the 30 building materials into four major groups using 15 variables. Copyright © 2013 Elsevier Ltd. All rights reserved.
Kennedy Space Center environmental health program
NASA Technical Reports Server (NTRS)
Marmaro, G. M.; Cardinale, M. A.; Summerfield, B. R.; Tipton, D. A.
1992-01-01
The Kennedy Space Center's environmental health organization is responsible for programs which assure its employees a healthful workplace under diverse and varied working conditions. These programs encompass the disciplines of industrial hygiene, radiation protection (health physics), and environmental sanitation/pollution control. Activities range from the routine, such as normal office work, to the highly specialized, such as the processing of highly toxic and hazardous materials.
Experience With Laser Safety In The USA--A Review
NASA Astrophysics Data System (ADS)
Sliney, David H.
1986-10-01
Following several research programs in the 1960's aimed at studying the adverse biological effects of lasers and other optical radiation sources, laser occupational exposure limits were set and general safety standards were developed. Today, the experience from laser accidents and the development of new lasers and new applications have altered the format of the exposure limits and the safety procedures. It is critically important to distinguish between different biological injury mechanisms. The biological effects of ultraviolet radiation upon the skin and eye are additive over a period of at least one workday, and require different safety procedures. The scattered UV irradiance from excimer lasers may be quite hazardous, depending upon wavelength and action spectra. Since laser technology is young, the exposure of an individual in natural sunlight must be studied to evaluate the potential for chronic effects. The safety measures necessary in the use of lasers depend upon a hazard evaluation. The appropriate control measures and alternate means of enclosure, baffling, and operational control measures are presented. Present laser safety standards are explained briefly. Eye protective techniques and eyewear are considered for a variety of sources. The optical properties of enclosure materials are also discussed.
VLF Harold E. Holt RADHAZ measurements
NASA Astrophysics Data System (ADS)
Hansen, P. M.; Chavez, J.
1993-09-01
This document details the radiation hazard (RADHAZ) measurements made at the very-low-frequency (VLF) Harold E. Holt (HEH) transmitting facility by personnel from U.S. Naval Command, Control and Ocean Surveillance Center (NCCOSC), Research, Development, Test and Evaluation Division (RDT&E Div.), the U.S. Naval Aerospace Medical Research Laboratory (NAMRL), the Australian Defence Force (ADF), and the Royal Australian Navy (RAN). The measurements were made to determine if hazardous levels of electromagnetic fields existed in locations normally accessed by personnel. NAMRL and ADF personnel were primarily responsible for the measurements on the ground and in and around the transmitter building; NRaD personnel were primarily responsible for measurements on the towers.
NASA Astrophysics Data System (ADS)
Mazur, J. E.; Guild, T. B.; Crain, W.; Crain, S.; Holker, D.; Quintana, S.; O'Brien, T. P., III; Kelly, M. A.; Barnes, R. J.; Sotirelis, T.
2017-12-01
The Responsive Environmental Assessment Commercial Hosting (REACH) project uses radiation dosimeters on a commercial satellite constellation in low Earth orbit to provide unprecedented spatial and time sampling of space weather radiation hazards. The spatial and time scales of natural space radiation environments coupled with constraints for the hosting accommodation drove the instrumentation requirements and the plan for the final orbital constellation. The project has delivered a total of thirty two radiation dosimeter instruments for launch with each instrument containing two dosimeters with different passive shielding and electronic thresholds to address proton-induced single-event effects, vehicle charging, and total ionizing dose. There are two REACH instruments currently operating with four more planned for launch by the time of the 2017 meeting. Our aim is to field a long-lived system of highly-capable radiation detectors to monitor the hazards of single-event effects, total ionizing dose, and spacecraft charging with maximized spatial coverage and with minimal time latency. We combined a robust detection technology with a commercial satellite hosting to produce a new demonstration for satellite situational awareness and for other engineering and science applications.
MO-G-BRE-08: Taxonomy of Corrective Actions in Radiotherapy
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sutlief, S; Brown, D
2014-06-15
Purpose: Various causal taxonomies have been developed for healthcare incidents and for radiation therapy in particular. The causal analysis of incidents leads to corrective actions which can also be organized into a taxonomy. Such a corrective action classification system would provide information about the situational context, the action type, and the leverage of the action in order to detect patterns in the corrective actions frequently employed in radiation therapy. It would also provide practical guidance to the radiation therapy community for determining the appropriateness and potential effectiveness of proposed corrective actions. Materials: A review of causal analysis reports and correctivemore » action plans was conducted using the following sources: US NRC medical event reports, IAEA reports, ROSIS submissions, US Veterans Health Administration reports, and singleincident report sources. The corrective actions presented in the published sources were then mapped onto four corrective action taxonomy prototypes: role-based, safety-context-based, responsibility-based, and hierarchy of hazard control. The resulting corrective action taxonomy was then validated through use of the published sources. Results: The responsibility-based taxonomy and hierarchy of hazard taxonomy provided more intuitive and sensible categories than the role-based taxonomy or the safety-context taxonomy. The most frequent corrective actions were added safety barriers, training, process standardization, and development of a quality improvement program where one was lacking. Conclusion: Published corrective action statements in radiation therapy emphasize what to do more so than whom the recipient is or which process step is affected. The hierarchy of hazard taxonomy provides a suitable framework for radiation therapy and has the advantage of providing insight into the likelihood that a particular corrective action will mitigate the recurrence of the error it was meant to correct. This information would be useful to medical center administration, safety personnel, and regulators who must assess the projected efficacy of corrective actions. Derek Brown is a director of TreatSafely, LLC.« less
Brick mortar exposure and chronic lymphocytic leukemia.
Markovic-Denic, L; Jankovic, S; Marinkovic, J; Radovanovic, Z
1995-01-01
A case-control study of 130 patients with chronic lymphocytic leukemia (CLL) and 130 controls matched with respect to sex, age (2 years), type of residence (urban-rural) and area of residence (according to the national per capita income) was carried out. Conditional logistic regression analysis showed that, apart of four risk factors already described in the literature (work in a hazardous industry, hair dye use, family history of leukemia and exposure to electromagnetic radiation), brick mortar exposure was also significantly related to CLL.
Thyroid neoplasms after radiation therapy for adolescent acne vulgaris. [X radiation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Paloyan, E.; Lawrence, A.M.
There is a potential hazard of thyroid cancer after exposure to external irradiation for the treatment of adolescent acne vulgaris. We noted a 60% incidence of thyroid carcinoma among 20 patients with such a history, who were operated on for thyroid nodules during a five-year period. Eighty-three percent of the patients with carcinoma had either a follicular or a mixed papillary-follicular carcinoma; 17% had a papillary carcinoma; 33% had regional node metastases; none had evidence of distant metastases. The interval between radiation exposure and thyroidectomy ranged from nine to 41 years. This association of thyroid neoplasms and a prior historymore » of radiation for acne vulgaris may be coincidental and therefore remains to be proved by retrospective surveys of large numbers of treated patients with appropriate controls.« less
Radiation hazard during a manned mission to Mars.
Jäkel, Oliver
2004-01-01
The radiation hazard of interplanetary flights is currently one of the major obstacles to manned missions to Mars. Highly energetic, heavy-charged particles from galactic cosmic radiation can not be sufficiently shielded in space vehicles. The long-term radiation effects to humans of these particles are largely unknown. In addition, unpredictable storms of solar particles may expose the crew to doses that lead to acute radiation effects. A manned flight to Mars currently seems to be a high-risk adventure. This article provides an overview on the radiation sources and risks for a crew on a manned flight to Mars, as currently estimated by scientists of the US National Administration for Space and Aeronautics (NASA) and the Space Studies Board (SSB) of the US National Research Council.
The Ionizing Radiation Environment on the Moon
NASA Technical Reports Server (NTRS)
Adams, J. H., Jr.; Bhattacharya, M.; Lin, Zi-Wei; Pendleton, G.
2006-01-01
The ionizing radiation environment on the moon that contributes to the radiation hazard for astronauts consists of galactic cosmic rays, solar energetic particles and albedo particles from the lunar surface. We will present calculations of the absorbed dose and the dose equivalent to various organs in this environment during quiet times and during large solar particle events. We will evaluate the contribution of solar particles other than protons and the contributions of the various forms of albedo. We will use the results to determine which particle fluxes must be known in order to estimate the radiation hazard.
NSLS-II beamline scattered gas bremsstrahlung radiation shielding calculation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Popescu, Razvan; Xia, Zhenghua, E-mail: xiazhenghuacn@hotmail.com; Job, Panakkal
2016-07-27
National Synchrotron Light Source II (NSLS-II) is a new state-of-the-art 3rd generation synchrotron. The NSLS-II facility is shielded up to 3 GeV electron beam energy at 500 mA. When the gas bremsstrahlung (GB) from the storage ring is scattered by the beamline components in the first optical enclosure (FOE), the scattered radiation will pose additional radiation hazard (bypassing primary GB collimators and stops) and challenge the FOE shielding. The scattered GB radiation hazard can be mitigated by supplementary shielding or with an exclusion zone downstream of the FOE.
NASA Technical Reports Server (NTRS)
McGarry, Jan
2015-01-01
NASA's Next Generation Satellite Laser Ranging (NGSLR) station is the prototype for NASA's Satellite Laser Ranging (SLR) systems which will be deployed around the world in the coming decade. The NGSLR system will be an autonomous, photon-counting SLR station with an expected absolute range accuracy of better than one centimeter and a normal point (time-averaged) range precision better than one millimeter. The system provides continuous (weather permitting), 24 hour tracking coverage to an existing constellation of approximately two dozen artificial satellites equipped with passive retroreflector arrays, using pulsed, 532 nm, class IV laser systems. Current details on the approved laser systems can be found in the Appendix 1 of this document. This safety plan addresses the potential hazards to emitted laser radiation, which can occur both inside and outside the shelter. Hazards within the shelter are mitigated through posted warning signs, activated warning lights, procedural controls, personal protective equipment (PPE), laser curtains, beam blocking systems, interlock controls, pre-configured laser control settings, and other controls discussed in this document. Since the NGSLR is a satellite tracking system, laser hazards exist outside the shelter to personnel on the shelter roof and to passing aircraft. Potential exposure to personnel outside the system is mitigated through the use of posted warning signs, access control, procedural controls, a stairwell interlock, beam attenuation/blocking devices, and a radar based aircraft detection system.
Lin, Z W; Adams, J H
2007-03-01
The radiation hazard for astronauts from galactic cosmic rays (GCR) is a major obstacle to long-duration human space exploration. Space radiation transport codes have been developed to calculate the radiation environment on missions to the Moon, Mars, and beyond. We have studied how uncertainties in fragmentation cross sections at different energies affect the accuracy of predictions from such radiation transport calculations. We find that, in deep space, cross sections at energies between 0.3 and 0.85 GeV/nucleon have the largest effect in solar maximum GCR environments. At the International Space Station, cross sections at higher energies have the largest effect due to the geomagnetic cutoff.
Mobile inductively coupled plasma system
D'Silva, Arthur P.; Jaselskis, Edward J.
1999-03-30
A system for sampling and analyzing a material located at a hazardous site. A laser located remote from the hazardous site is connected to an optical fiber, which directs laser radiation proximate the material at the hazardous site. The laser radiation abates a sample of the material. An inductively coupled plasma is located remotely from the material. An aerosol transport system carries the ablated particles to a plasma, where they are dissociated, atomized and excited to provide characteristic optical reduction of the elemental constituents of the sample. An optical spectrometer is located remotely from the site. A second optical fiber is connected to the optical spectrometer at one end and the plasma source at the other end to carry the optical radiation from the plasma source to the spectrometer.
Long-term Cardiac Mortality After Hypofractionated Radiation Therapy in Breast Cancer
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tjessem, Kristin Holm, E-mail: krtjes@ous-hf.no; Johansen, Safora; Malinen, Eirik
Purpose: To explore very-long-term mortality from ischemic heart disease (IHD) after locoregional radiation therapy of breast cancer (BC) in relation to degree of hypofractionation and other treatment variables. Methods and Materials: Two hypofractionated regimens used for locoregional radiation therapy for BC from 1975 to 1991 were considered. Patients received 4.3 Gy × 2/week (10 fractions; target dose 43 Gy; n=1107) or 2.5 Gy × 5/week (20 fractions; target dose 50 Gy; n=459). To estimate cardiac doses, radiation fields were reconstructed in a planning system. Time to death from IHD was the endpoint, comparing the groups with each other and withmore » age-matched, cancer-free control individuals, modeled with the Cox proportional hazards model. Results: Patients given 4.3 Gy × 10 had an increased risk of dying of IHD compared with both the 2.5 Gy group (hazard ratio [HR] = 2.37; 95% confidence interval [CI]: 1.06-5.32; P=.036) and the control group (HR = 1.59; 95% CI: 1.13-2.23; P=.008). Photon beams for parasternal fields gave an increased risk of dying of IHD compared with electron beams (HR = 2.56; 95% CI: 1.12-5.84; P=.025). Multivariate analysis gave an increased risk for the 4.3-Gy versus 2.5-Gy regimen with borderline significance (HR = 2.90; 95% CI: 0.97-8.79; P=.057) but not for parasternal irradiation. Conclusions: The degree of hypofractionation and parasternal photon beams contributed to increased cardiac mortality in this patient cohort. Differences emerged after 12 to 15 years, indicating the need of more studies with observation time of 2 decades.« less
An Exposure Prevention Plan for an Anhydrous Ammonia Handling System
NASA Technical Reports Server (NTRS)
Padolewski, Cathy L.; Bower, Amy; Ponikvar, Gary; Mellott, Ken
1997-01-01
In July of 1996, the Industrial Hygiene Team of the Environmental Management Office at NASA Lewis Research Center was contacted by the Space Station Program Office to conduct ammonia awareness training for a team of engineers and technicians. The team was tasked with assembling and operating an ammonia handling system for testing of a photovoltaic radiator at the NASA Plum Brook Station Space Power Facility. The ammonia handling system supports a radiator designed to radiate excess heat from a photovoltaic array module used to provide power to the International Space Station. The system would consist of a hazardous materials trailer equipped with an anhydrous ammonia tank, heater, accumulator, chiller, and flow bench. Meetings were held with representatives from the Space Station Program Office, the engineers and Plum Brook safety personnel. Guidance was also provided by representatives from Kennedy Space Center. Determinations were made concerning the locations and types of potential exposures and a plan was developed which included training, personal protective equipment, engineering controls and emergency response. Various organizations including the Plum Brook Safety Committee, the Lewis Environmental Management Office, the Test Readiness Review Board and the Program Office all had requirements that had to be met in order to satisfy themselves that all personnel involved in the operation of the system would be safe. What resulted was a comprehensive plan that provided more than adequate safety measures and succeeded in protecting all personnel from the hazards of the ammonia system. Testing of the photovoltaic radiator was successful and although ammonia leaks were detected and maintenance of the system was ongoing, no one was injured. It was felt that the training and controls in place allowed for a comfort level that did not interfere with the operations.
NASA Technical Reports Server (NTRS)
1978-01-01
NASA technology has made commercially available a new, inexpensive, conveniently-carried device for protection, of people exposed to potentially dangerous levels of microwave radiation. Microwaves are radio emissions of extremely high frequency. They can be hazardous but the degree of hazard is not yet well understood. Generally, it is believed that low intensity radiation of short duration is not harmful but that exposure to high levels can induce deep internal burns, affecting the circulatory and nervous systems, and particularly the eyes. The Department of Labor's Occupational Safety and Health Administration (OSHA) has established an allowable safe threshold of exposure. However, people working near high intensity sources of microwave energy-for example, radar antennas and television transmitters-may be unknowingly exposed to radiation levels beyond the safe limit. This poses not only a personal safety problem but also a problem for employers in terms of productivity loss, workman's compensation claims and possible liability litigation. Earlier-developed monitoring devices which warn personnel of dangerous radiation levels have their shortcomings. They can be cumbersome and awkward to use while working. They also require continual visual monitoring to determine if a person is in a dangerous area of radiation, and they are relatively expensive, another deterrent to their widespread adoption. In response to the need for a cheaper and more effective warning system, Jet Propulsion Laboratory developed, under NASA auspices, a new, battery-powered Microwave Radiation Hazard Detector. To bring the product to the commercial market, California Institute Research Foundation, the patent holder, granted an exclusive license to Cicoil Corporation, Chatsworth, California, an electronic components manufacturer.
Physical hazard safety awareness among healthcare workers in Tanta university hospitals, Egypt.
El-Sallamy, Rania M; Kabbash, Ibrahim Ali; El-Fatah, Sanaa Abd; El-Feky, Asmaa
2017-05-17
Hospital workers are exposed to many occupational hazards that may threaten their health and safety. Physical hazards encountered in hospital working environment include temperature, illumination, noise, electrical injuries, and radiation. To assess the awareness of healthcare workers (HCWs) about physical hazards in Tanta university hospitals, this cross-sectional study included 401 HCWs (physicians, nurses, technicians, and workers) from seven departments (general surgery, orthopedics, radiology, ophthalmology, kitchen, incinerator, and laundry). Data were collected through interview questionnaire to assess six types of physical hazards (noise, electric hazards, temperature, radiation, fire, and lighting,). Most of the physicians (63.7%) were aware of the level of noise. All physicians, nurses, technicians, and majority of workers reported that hearing protective devices were not available, and all HCWs reported that periodic hearing examination was not performed. Most of the nurses (75.2%) and workers (68.5%) did not attended emergency training, and more than two thirds of all HCWs were not briefed about emergency evacuation. Most HCWs were not given appropriate radiation safety training before starting work (88% of workers, 73.7% of nurses, 65.7% of physicians, and 68.3% of technicians). The majority of physicians, nurses, and technicians (70.5, 65.4, and 53.7%) denied regular environmental monitoring for radiation level inside work place. Health education programs on health and safety issues regarding physical hazards should be mandatory to all healthcare workers to improve their awareness and protect them from undue exposures they may face due to lack of adequate awareness and knowledge. There is urgent need of expanding the occupational healthcare services in Egypt to cover all the employees as indicated by the international recommendations and the Egyptian Constitution, legislation, and community necessity.
PEACETIME RADIATION HAZARDS IN THE FIRE SERVICE, BASIC COURSE, RESOURCE MANUAL.
ERIC Educational Resources Information Center
BERNDT, WILLIAM
FOR USE BY FIREMEN AND OTHER EMERGENCY PERSONNEL WHO MAY HAVE TO DEAL WITH FIRES OR SIMILAR EMERGENCIES INVOLVING RADIATION HAZARDS, THIS MANUAL IS CORRELATED WITH THE FOLLOWING INSTRUCTIONAL MATERIALS FOR THE 15-HOUR COURSE -- (1) AN INSTRUCTOR'S GUIDE (VT 002 117), (2) A STUDENT STUDY GUIDE (VT 001 878), AND (3) A SET OF TWENTY-TWO 20- BY…
ERIC Educational Resources Information Center
Ohio State Dept. of Education, Columbus. Div. of Vocational Education.
This training manual for emergency medical technicians, one of 14 modules that comprise the Emergency Victim Care textbook, covers water accidents, electrical emergencies, and hazardous materials and radiation accidents. Objectives stated for the three chapters are for the students to be able to describe: emergency care for specified water…
Optical radiation hazards of laser welding processes. Part 1: Neodymium-YAG laser.
Rockwell, R J; Moss, C E
1983-08-01
High power laser devices are being used for numerous metalworking processes such as welding, cutting and heat treating. Such laser devices are totally enclosed either by the manufacturer or the end-user. When this is done, the total laser system is usually certified by the manufacturer following the federal requirements of the Code of Federal Regulations (CFR) 1040.10 and 10.40.11 as a Class I laser system. Similarly, the end-user may also reclassify an enclosed high-power laser into the Class I category following the requirements of the American National Standards Institute (ANSI) Z-136.1 (1980) standard. There are, however, numerous industrial laser applications where Class IV systems are required to be used in an unenclosed manner. In such applications, there is concern for both ocular and skin hazards caused by direct and scattered laser radiation, as well as potential hazards caused by the optical radiation created by the laser beam's interaction with the metal (i.e. the plume radiation). Radiant energy measurements are reported for both the scattered laser radiation and the resultant plume radiations which were produced during typical unenclosed Class IV Neodymium-YAG laser welding processes. Evaluation of the plume radiation was done with both radiometric and spectroradiometric measurement equipment. The data obtained were compared to applicable safety standards.
Yothers, Greg; O’Connell, Michael J.; Beart, Robert W.; Wozniak, Timothy F.; Pitot, Henry C.; Shields, Anthony F.; Landry, Jerome C.; Ryan, David P.; Arora, Amit; Evans, Lisa S.; Bahary, Nathan; Soori, Gamini; Eakle, Janice F.; Robertson, John M.; Moore, Dennis F.; Mullane, Michael R.; Marchello, Benjamin T.; Ward, Patrick J.; Sharif, Saima; Roh, Mark S.; Wolmark, Norman
2015-01-01
Background: National Surgical Adjuvant Breast and Bowel Project R-04 was designed to determine whether the oral fluoropyrimidine capecitabine could be substituted for continuous infusion 5-FU in the curative setting of stage II/III rectal cancer during neoadjuvant radiation therapy and whether the addition of oxaliplatin could further enhance the activity of fluoropyrimidine-sensitized radiation. Methods: Patients with clinical stage II or III rectal cancer undergoing preoperative radiation were randomly assigned to one of four chemotherapy regimens in a 2x2 design: CVI 5-FU or oral capecitabine with or without oxaliplatin. The primary endpoint was local-regional tumor control. Time-to-event endpoint distributions were estimated using the Kaplan-Meier method. Hazard ratios were estimated from Cox proportional hazard models. All statistical tests were two-sided. Results: Among 1608 randomized patients there were no statistically significant differences between regimens using 5-FU vs capecitabine in three-year local-regional tumor event rates (11.2% vs 11.8%), 5-year DFS (66.4% vs 67.7%), or 5-year OS (79.9% vs 80.8%); or for oxaliplatin vs no oxaliplatin for the three endpoints of local-regional events, DFS, and OS (11.2% vs 12.1%, 69.2% vs 64.2%, and 81.3% vs 79.0%). The addition of oxaliplatin was associated with statistically significantly more overall and grade 3–4 diarrhea (P < .0001). Three-year rates of local-regional recurrence among patients who underwent R0 resection ranged from 3.1 to 5.1% depending on the study arm. Conclusions: Continuous infusion 5-FU produced outcomes for local-regional control, DFS, and OS similar to those obtained with oral capecitabine combined with radiation. This study establishes capecitabine as a standard of care in the pre-operative rectal setting. Oxaliplatin did not improve the local-regional failure rate, DFS, or OS for any patient risk group but did add considerable toxicity. PMID:26374429
Natural radioactivity and radiation hazards in some building materials used in Isparta, Turkey
NASA Astrophysics Data System (ADS)
Mavi, B.; Akkurt, I.
2010-09-01
The activity concentrations of uranium, thorium and potassium can vary from material to material and it should be measured as the radiation is hazardous for human health. Thus first studies have been planned to obtain radioactivity of building material used in the Isparta region of Turkey. The radioactivity of some building materials used in this region has been measured using a γ-ray spectrometry, which contains a NaI(Tl) detector connected to MCA. The specific activity for 226Ra, 232Th and 40K, from the selected building materials, were in the range 17.91-58.88, 6.77-19.49 and 65.72-248.76 Bq/kg, respectively. Absorbed dose rate in air ( D), annual effective dose (AED), radium equivalent activities (Ra eq), and external hazard index ( Hex) associated with the natural radionuclide are calculated to assess the radiation hazard of the natural radioactivity in the building materials. It was found that none of the results exceeds the recommended limit value.
Bavarnegin, Elham; Moghaddam, Masoud Vahabi; Fathabadi, Nasrin
2013-04-01
Building materials, collected from different sites in Ramsar, a northern coastal city in Iran, were analyzed for their natural radionuclide contents. The measurements were carried out using a high resolution high purity Germanium (HPGe) gamma-ray spectrometer system. The activity concentration of (226)Ra, (232)Th, and (40)K content varied from below the minimum detection limit up to 86,400 Bqkg(-1), 187 Bqkg(-1), and 1350 Bqkg(-1), respectively. The radiological hazards incurred from the use of these building materials were estimated through various radiation hazard indices. The result of this survey shows that values obtained for some samples are more than the internationally accepted maximum limits and as such, the use of them as a building material pose significant radiation hazard to individuals.
Mobile inductively coupled plasma system
D`Silva, A.P.; Jaselskis, E.J.
1999-03-30
A system is described for sampling and analyzing a material located at a hazardous site. A laser located remotely from the hazardous site is connected to an optical fiber, which directs laser radiation proximate the material at the hazardous site. The laser radiation abates a sample of the material. An inductively coupled plasma is located remotely from the material. An aerosol transport system carries the ablated particles to a plasma, where they are dissociated, atomized and excited to provide characteristic optical reduction of the elemental constituents of the sample. An optical spectrometer is located remotely from the site. A second optical fiber is connected to the optical spectrometer at one end and the plasma source at the other end to carry the optical radiation from the plasma source to the spectrometer. 10 figs.
Boberg, P R; Tylka, A J; Adams, J H; Beahm, L P; Fluckiger, E O; Kleis, T; Kobel, E
1996-01-01
The large solar energetic particle (SEP) events and simultaneous large geomagnetic disturbances observed during October 1989 posed a significant, rapidly evolving space radiation hazard. Using data from the GOES-7, NOAA-10, IMP-8 and LDEF satellites, we determined the geomagnetic transmission, heavy ion fluences, mean Fe ionic charge state, and effective radiation hazard observed in low Earth orbit (LEO) for these SEPs. We modeled the geomagnetic transmission by tracing particles through the combination of the internal International Geomagnetic Reference Field (IGRF) and the Tsyganenko (1989) magnetospheric field models, extending the modeling to large geomagnetic disturbances. We used our results to assess the radiation hazard such very large SEP events would pose in the anticipated 52 degrees inclination space station orbit.
NASA Technical Reports Server (NTRS)
1971-01-01
A case study of knowledge contributions from the crew life support aspect of the manned space program is reported. The new information needed to be learned, the solutions developed, and the relation of new knowledge gained to earthly problems were investigated. Illustrations are given in the following categories: supplying atmosphere for spacecraft; providing carbon dioxide removal and recycling; providing contaminant control and removal; maintaining the body's thermal balance; protecting against the space hazards of decompression, radiation, and meteorites; minimizing fire and blast hazards; providing adequate light and conditions for adequate visual performance; providing mobility and work physiology; and providing adequate habitability.
Does chemotherapy improve survival in high-risk stage I and II Merkel cell carcinoma of the skin?
DOE Office of Scientific and Technical Information (OSTI.GOV)
Poulsen, Michael G.; Rischin, Danny; Porter, Ian
2006-01-01
Purpose: The effectiveness of synchronous carboplatin, etoposide, and radiation therapy in improving survival was evaluated by comparison of a matched set of historic control subjects with patients treated in a prospective Phase II study that used synchronous chemotherapy and radiation and adjuvant chemotherapy. Patients and Methods: Patients were included in the analysis if they had disease localized to the primary site and nodes, and they were required to have at least one of the following high-risk features: recurrence after initial therapy, involved nodes, primary size greater than 1 cm, or gross residual disease after surgery. All patients who received chemotherapymore » were treated in a standardized fashion as part of a Phase II study (Trans-Tasman Radiation Oncology Group TROG 96:07) from 1997 to 2001. Radiation was delivered to the primary site and nodes to a dose of 50 Gy in 25 fractions over 5 weeks, and synchronous carboplatin (AUC 4.5) and etoposide, 80 mg/m{sup 2} i.v. on Days 1 to 3, were given in Weeks 1, 4, 7, and 10. The historic group represents a single institution's experience from 1988 to 1996 and was treated with surgery and radiation alone, and patients were included if they fulfilled the eligibility criteria of TROG 96:07. Patients with occult cutaneous disease were not included for the purpose of this analysis. Because of imbalances in the prognostic variables between the two treatment groups, comparisons were made by application of Cox's proportional hazard modeling. Overall survival, disease-specific survival, locoregional control, and distant control were used as endpoints for the study. Results: Of the 102 patients who had high-risk Stage I and II disease, 40 were treated with chemotherapy (TROG 96:07) and 62 were treated without chemotherapy (historic control subjects). When Cox's proportional hazards modeling was applied, the only significant factors for overall survival were recurrent disease, age, and the presence of residual disease. For disease-specific survival, recurrent disease was the only significant factor. Primary site on the lower limb had an adverse effect on locoregional control. For distant control, the only significant factor was residual disease. Conclusions: The multivariate analysis suggests chemotherapy has no effect on survival, but because of the wide confidence limits, a chemotherapy effect cannot be excluded. A study of this size is inadequately powered to detect small improvements in survival, and a larger randomized study remains the only way to truly confirm whether chemotherapy improves the results in high-risk MCC.« less
Wave energy budget analysis in the Earth’s radiation belts uncovers a missing energy
Artemyev, A.V.; Agapitov, O.V.; Mourenas, D.; Krasnoselskikh, V.V.; Mozer, F.S.
2015-01-01
Whistler-mode emissions are important electromagnetic waves pervasive in the Earth’s magnetosphere, where they continuously remove or energize electrons trapped by the geomagnetic field, controlling radiation hazards to satellites and astronauts and the upper-atmosphere ionization or chemical composition. Here, we report an analysis of 10-year Cluster data, statistically evaluating the full wave energy budget in the Earth’s magnetosphere, revealing that a significant fraction of the energy corresponds to hitherto generally neglected very oblique waves. Such waves, with 10 times smaller magnetic power than parallel waves, typically have similar total energy. Moreover, they carry up to 80% of the wave energy involved in wave–particle resonant interactions. It implies that electron heating and precipitation into the atmosphere may have been significantly under/over-valued in past studies considering only conventional quasi-parallel waves. Very oblique waves may turn out to be a crucial agent of energy redistribution in the Earth’s radiation belts, controlled by solar activity. PMID:25975615
Wave energy budget analysis in the Earth's radiation belts uncovers a missing energy.
Artemyev, A V; Agapitov, O V; Mourenas, D; Krasnoselskikh, V V; Mozer, F S
2015-05-15
Whistler-mode emissions are important electromagnetic waves pervasive in the Earth's magnetosphere, where they continuously remove or energize electrons trapped by the geomagnetic field, controlling radiation hazards to satellites and astronauts and the upper-atmosphere ionization or chemical composition. Here, we report an analysis of 10-year Cluster data, statistically evaluating the full wave energy budget in the Earth's magnetosphere, revealing that a significant fraction of the energy corresponds to hitherto generally neglected very oblique waves. Such waves, with 10 times smaller magnetic power than parallel waves, typically have similar total energy. Moreover, they carry up to 80% of the wave energy involved in wave-particle resonant interactions. It implies that electron heating and precipitation into the atmosphere may have been significantly under/over-valued in past studies considering only conventional quasi-parallel waves. Very oblique waves may turn out to be a crucial agent of energy redistribution in the Earth's radiation belts, controlled by solar activity.
Kumagai, S; Hirata, M; Tabuchi, T; Tainaka, H; Andoh, K; Oda, H
2000-09-01
In order to clarify the actual condition of occupational health management for hazardous and musculo-skeletally stressful work factors in small-scale enterprises (SSEs) in Japan, a questionnaire survey was conducted in an area near Osaka city. The hazardous work factors examined were dust, organic solvents, lead, specified chemical substances, anoxia, noise, hand-arm vibration, ionizing radiation, high and low temperatures, and high air pressure. The musculo-skeletally stressful work factors examined were VDT work, prolonged standing, unnatural postures, handling of heavy weights, and stress on neck, shoulders and arms. The number of SSEs that replied to the questionnaire was 765 (recovery rate: 69.3%). Enterprises with noise, dust, hand-arm vibration and organic solvents numbered 14.0%, 10.7%, 6.9% and 6.4%, respectively, and those with other hazardous factors numbered less than 3%. Special medical examinations and working environment measurements for hazardous factors were conducted in 0.0% to 26.7% and 0.0% to 13.3%, respectively, of the enterprises. Working environment controls were conducted in 0.0% to 40.2%. Enterprises with prolonged standing and VDT work, were 42.0% and 35.8%, whereas those with other stressful factors were approximately 30%. Special medical examinations for musculo-skeletally stressful factors were conducted in 3.0% to 5.1% of the enterprises, and work controls were conducted in 20.4% to 25.3%. Non execution of the special medical examinations and working environment measurements were mainly due to "lack of knowledge of the law (19.7% and 30.2%)" and "lack of time to perform (16.0% and 23.3%)". Non execution of the controls for the hazardous work factors was due to "lack of knowledge as to how to control (9.0%)", "high costs (7.4%)", "lack of time to perform (6.4%)" and "absence of a suitable adviser (5.9%)". Non execution of the controls for stressful work factors was due to "lack of knowledge as to how to control (15.6%)" and "lack of time to perform (10.2%)". Consequently, as a result of the survey, it was suggested that it is necessary to enlighten the employers of SEEs as to the importance of occupational health controls. It is also necessary to propose low-cost, feasible control methods.
SEEDS ), (*RADIATION EFFECTS, (*NUCLEAR EXPLOSIONS, RADIATION HAZARDS), X RAYS, WHEAT, RADIATION DOSAGE, MUTATIONS, RADIOBIOLOGY, GROWTH(PHYSIOLOGY), CEREALS, SENSITIVITY, AGING(PHYSIOLOGY), EXPERIMENTAL DATA, NUCLEAR BOMBS.
Induction of a Radio-Adaptive Response by Low-dose Gamma Irradiation in Mouse Cardiomyocytes
NASA Technical Reports Server (NTRS)
Westby, Christian M.; Seawright, John W.; Wu, Honglu
2011-01-01
One of the most significant occupational hazards to an astronaut is the frequent exposure to radiation. Commonly associated with increased risk for cancer related morbidity and mortality, radiation is also known to increase the risk for cardiovascular related disorders including: pericarditis, hypertension, and heart failure. It is believed that these radiation-induced disorders are a result of abnormal tissue remodeling. It is unknown whether radiation exposure promotes remodeling through fibrotic changes alone or in combination with programmed cell death. Furthermore, it is not known whether it is possible to mitigate the hazardous effects of radiation exposure. As such, we assessed the expression and mechanisms of radiation-induced tissue remodeling and potential radio-adaptive responses of p53-mediated apoptosis and fibrosis pathways along with markers for oxidative stress and inflammation in mice myocardium. 7 week old, male, C57Bl/6 mice were exposed to 6Gy (H) or 5cGy followed 24hr later with 6Gy (LH) 137Cs gamma radiation. Mice were sacrificed and their hearts extirpated 4, 24, or 72hr after final irradiation. Real Time - Polymerase Chain Reaction was used to evaluate target genes. Apoptotic genes Bad and Bax, pro-cell survival genes Bcl2 and Bcl2l2, fibrosis gene Vegfa, and oxidative stress genes Sod2 and GPx4 showed a reduced fold regulation change (Bad,-6.18; Bax,-6.94; Bcl2,-5.09; Bcl2l2,-4.03; Vegfa, -11.84; Sod2,-5.97; GPx4*,-28.72; * = Bonferroni adjusted p-value < or = 0.003) 4hr after H, but not after 4hr LH compared to control. Other p53-mediated apoptosis genes Casp3, Casp9, Trp53, and Myc exhibited down-regulation but did not achieve a notable level of significance 4hr after H. 24hr after H, genetic down-regulation was no longer present compared to 24hr control. These data suggest a general reduction in genetic expression 4hrs after a high dose of gamma radiation. However, pre-exposure to 5cGy gamma radiation appears to facilitate a radio-adaptive response that mitigates the reduction in genetic expression associated with single high-dose gamma radiation exposure. This radio-adaptive response may serve as a potential countermeasure to radiation-induced myocardial remodeling and preserve the cardiovascular health of astronauts; thus, reducing the risks of human space exploration.
Optical radiation measurements and instrumentation.
Andersen, F A; Landry, R J
1981-07-01
Accurate measurement of optical radiation is required when sources of optical radiation are used in biological research. Such measurement of broad-band noncoherent optical radiations usually must be performed by a highly trained specialist using sophisticated, complex, and expensive instruments. Presentation of the results of such measurement requires correct use of quantities and units with which many biological researchers are unfamiliar. The measurement process, quantities, units, measurement systems and instruments, and uncertainties associated with optical radiation measurements are reviewed in this paper. A conventional technique for evaluating the potential hazards associated with broad-band sources of optical radiation and a spectroradiometer developed to measure spectral quantities is described. A new prototype ultraviolet radiation hazard monitor which has recently been developed is also presented. This new instrument utilizes a spectrograph and a spectral weighting mechanical mask and provides a direct reading of the effective irradiance for wavelengths less than 315 nm.
Laser Hazards Bibliography - November 1980.
1980-11-01
W., and Schmidt, I., Protection against photic damage in retinitis pigmentosa , Adv Exp Med Biol, 77: 233-247 (1977). 2. Agarwal, L. P., and Malik, S...Laser Exposure imits ...................... 180 C. Optical Radiation Hazards - General Reviews...... 181 D. Retinal Burns from Lasers...radiation, Soy J Quantum Electron, 8: 552 (1978). 3. Anonymous, Use of various types of quantium generators in retinal diseases, Oftalmol Zh, 33(5): 323-324
Khan, Muhammad; Lin, Jie; Liao, Guixiang; Li, Rong; Wang, Baiyao; Xie, Guozhu; Zheng, Jieling; Yuan, Yawei
2017-07-01
Whole brain radiotherapy has been a standard treatment of brain metastases. Stereotactic radiosurgery provides more focal and aggressive radiation and normal tissue sparing but worse local and distant control. This meta-analysis was performed to assess and compare the effectiveness of whole brain radiotherapy alone, stereotactic radiosurgery alone, and their combination in the treatment of brain metastases based on randomized controlled trial studies. Electronic databases (PubMed, MEDLINE, Embase, and Cochrane Library) were searched to identify randomized controlled trial studies that compared treatment outcome of whole brain radiotherapy and stereotactic radiosurgery. This meta-analysis was performed using the Review Manager (RevMan) software (version 5.2) that is provided by the Cochrane Collaboration. The data used were hazard ratios with 95% confidence intervals calculated for time-to-event data extracted from survival curves and local tumor control rate curves. Odds ratio with 95% confidence intervals were calculated for dichotomous data, while mean differences with 95% confidence intervals were calculated for continuous data. Fixed-effects or random-effects models were adopted according to heterogeneity. Five studies (n = 763) were included in this meta-analysis meeting the inclusion criteria. All the included studies were randomized controlled trials. The sample size ranged from 27 to 331. In total 202 (26%) patients with whole brain radiotherapy alone, 196 (26%) patients receiving stereotactic radiosurgery alone, and 365 (48%) patients were in whole brain radiotherapy plus stereotactic radiosurgery group. No significant survival benefit was observed for any treatment approach; hazard ratio was 1.19 (95% confidence interval: 0.96-1.43, p = 0.12) based on three randomized controlled trials for whole brain radiotherapy only compared to whole brain radiotherapy plus stereotactic radiosurgery and hazard ratio was 1.03 (95% confidence interval: 0.82-1.29, p = 0.81) for stereotactic radiosurgery only compared to combined approach. Local control was best achieved when whole brain radiotherapy was combined with stereotactic radiosurgery. Hazard ratio 2.05 (95% confidence interval: 1.36-3.09, p = 0.0006) and hazard ratio 1.84 (95% confidence interval: 1.26-2.70, p = 0.002) were obtained from comparing whole brain radiotherapy only and stereotactic radiosurgery only to whole brain radiotherapy + stereotactic radiosurgery, respectively. No difference in adverse events for treatment difference; odds ratio 1.16 (95% confidence interval: 0.77-1.76, p = 0.48) and odds ratio 0.92 (95% confidence interval: 0.59-1.42, p = 71) for whole brain radiotherapy + stereotactic radiosurgery versus whole brain radiotherapy only and whole brain radiotherapy + stereotactic radiosurgery versus stereotactic radiosurgery only, respectively. Adding stereotactic radiosurgery to whole brain radiotherapy provides better local control as compared to whole brain radiotherapy only and stereotactic radiosurgery only with no difference in radiation related toxicities.
Evaluation of the radiation hazard for ion-beam analysis with MeV external proton beams (X-IBA)
NASA Astrophysics Data System (ADS)
Hofsäss, Hans
2018-07-01
MeV ion beams which are extracted into air or He atmosphere are used in many labs for proton-induced X-ray emission (PIXE), proton induced gamma ray emission (PIGE) or Rutherford backscattering (RBS) to analyze samples which are difficult or impossible to handle in vacuum. When MeV proton beams are extracted into air through thin Kapton foils or nowadays thin silicon nitride membranes, the protons will interact with air, as well as elements present in the analyzed samples. Typically the range of MeV protons in air is several cm, in Helium atmosphere several 10 cm and in human skin around 100 μm. Besides the severe radiation hazard in case of a direct exposure of skin with protons, there are a manifold of nuclear reactions or inelastic proton scattering processes which may cause activation of air and target materials but also prompt radiation. The radiation hazard associated with the direct and scattered beam, nuclear reaction products and radionuclide production in air have been discussed in a publication by Doyle et al. in 1991 which was used as a reference in several later publications. I have reevaluated the radiation hazards for external proton beams with up to 4.5 MeV using proton reaction cross sections taken from the JANIS book of proton induced cross sections. The radionuclide production in air is about 3 orders of magnitude lower compared to values given in the 1991 publication. Radionuclide production as well as generation of prompt alpha, gamma and neutron radiation in target materials for elements up to molybdenum is also evaluated.
NASA Astrophysics Data System (ADS)
Chang, Jianhui; Feng, Wei; Wang, Yingying; Allen, Antiño R.; Turner, Jennifer; Stewart, Blair; Raber, Jacob; Hauer-Jensen, Martin; Zhou, Daohong; Shao, Lijian
2017-05-01
Long-term space mission exposes astronauts to a radiation environment with potential health hazards. High-energy charged particles (HZE), including 28Si nuclei in space, have deleterious effects on cells due to their characteristics with high linear energy transfer and dense ionization. The influence of 28Si ions contributes more than 10% to the radiation dose equivalent in the space environment. Understanding the biological effects of 28Si irradiation is important to assess the potential health hazards of long-term space missions. The hematopoietic system is highly sensitive to radiation injury and bone marrow (BM) suppression is the primary life-threatening injuries after exposure to a moderate dose of radiation. Therefore, in the present study we investigated the acute effects of low doses of 28Si irradiation on the hematopoietic system in a mouse model. Specifically, 6-month-old C57BL/6 J mice were exposed to 0.3, 0.6 and 0.9 Gy 28Si (600 MeV) total body irradiation (TBI). The effects of 28Si TBI on BM hematopoietic stem cells (HSCs) and hematopoietic progenitor cells (HPCs) were examined four weeks after the exposure. The results showed that exposure to 28Si TBI dramatically reduced the frequencies and numbers of HSCs in irradiated mice, compared to non-irradiated controls, in a radiation dose-dependent manner. In contrast, no significant changes were observed in BM HPCs regardless of radiation doses. Furthermore, irradiated HSCs exhibited a significant impairment in clonogenic ability. These acute effects of 28Si irradiation on HSCs may be attributable to radiation-induced apoptosis of HSCs, because HSCs, but not HPCs, from irradiated mice exhibited a significant increase in apoptosis in a radiation dose-dependent manner. However, exposure to low doses of 28Si did not result in an increased production of reactive oxygen species and DNA damage in HSCs and HPCs. These findings indicate that exposure to 28Si irradiation leads to acute HSC damage.
Take, Toshio; Sato, Kaori; Kiuchi, Katsunori; Nakazawa, Yasuo
2007-11-20
A variety of radiation hazards resulting from interventional radiology (IVR) have been reported in recent years. Particularly affected are the skin and the crystalline lens, with their high radiation sensitivity. During neurological interventions, the radiological technologist should consider decreasing radiation exposure. We found exposure projections where the exposure dose became a radiation hazard for the crystalline lens, and examined an efficient method of cover for the exposure projections used for neurological interventions. The exposure projection for maximum crystalline lens radiation exposure was a lateral projection. In the crystalline lens the maximum exposure to radiation was on the X-ray tube side. The method of defense adopted was that of installing a lead plate of the appropriate shape on the surface of the X-ray tube collimator. In other exposure projections, this cover did not become a redundant shadow. With the cover that was created, the X-ray side crystalline lens lateral projection could be defended effectively.
Lead poisoning in automobile radiator mechanics.
Goldman, R H; Baker, E L; Hannan, M; Kamerow, D B
1987-07-23
Exposure to lead occurs during automobile radiator repair when soldered joints are heated, but this relatively common hazard has received little public recognition. We therefore studied lead exposure among automobile radiator mechanics in the Boston area. Twenty-seven shops were surveyed, and most were found to be small and poorly ventilated. Seventy-five workers were interviewed and tested for blood lead and free erythrocyte protoporphyrin levels. Fifty-six of the 75 actually repaired radiators, and they had a mean blood lead level of 37.1 micrograms per deciliter (range, 16 to 73). Thirty-nine percent of these mechanics had levels higher than 40 micrograms per deciliter; hematologic, neurologic, and renal effects are known to develop at or above this blood lead level. Multiple regression analysis showed that the number of radiator repair work stations (an index of exposure) was the variable most significantly associated with increased blood lead levels. We conclude that excessive exposure to lead occurs frequently among radiator repair workers and should be prevented by improved ventilation, engineering controls, and the use of respirators (if indicated) while working.
Lee, Yen-Chien; Chuang, Jen-Pin; Hsieh, Pi-Ching; Chiou, Meng-Jiun; Li, Chung-Yi
2015-07-01
This study aims to investigate whether patients with breast cancer and a history of cardiovascular diseases (CADs) are at an increased incidence of acute coronary syndrome (ACS) after receiving radiation therapy (RT). In Taiwan, 5828 patients who had a history of CAD were newly diagnosed of breast cancer and received mastectomy between 1999 and 2009. Among these patients, 1851 also received RT. The study cohort was prospectively followed to the end of 2010 for estimating the incidence of ACS in association with exposure to RT. A Cox proportional hazard model that was adjusted for covariates was used to estimate the hazard ratio (HR) of ACS. Over the study period, the incident rates of ACS for RT and control patients were estimated at 1.51 and 1.77 per 100 person-years, respectively. Covariate-adjusted regression analysis indicated that the hazard of ACS significantly increased in RT patients at an adjusted HR of 1.48 [95% confidence interval (CI) 1.18-1.87]. Both hypertension and diabetes significantly increased the hazard of ACS in this patient cohort, with adjusted HRs of 3.31 (95% CI 1.94-5.66) and 1.50 (95% CI 1.19-1.89), respectively. This 12-year follow-up study suggested excess of ACS events in association with RT exposure in patients with breast cancer who had a higher cardiovascular risk. In consideration of the benefit associated with RT, intensive cardiac care should be given to patients with breast cancer and high cardiovascular risk.
Recent international regulations: low dose-low rate radiation protection and the demise of reason.
Okkalides, Demetrios
2008-01-01
The radiation protection measures suggested by the International Committee for Radiation Protection (ICRP), national regulating bodies and experts, have been becoming ever more strict despite the decrease of any information supporting the existence of the Linear no Threshold model (LNT) and of any adverse effects of Low Dose Low Rate (LDLR) irradiation. This tendency arises from the disproportionate response of human society to hazards that are currently in fashion and is unreasonable. The 1 mSv/year dose limit for the public suggested by the ICRP corresponds to a 1/18,181 detriment-adjusted cancer risk and is much lower than other hazards that are faced by modern societies such as e.g. driving and smoking which carry corresponding rate risks of 1/2,100 and 1/2,000. Even worldwide deadly work accidents rate is higher at 1/ 8,065. Such excessive safety measures against minimal risks from man made radiation sources divert resources from very real and much greater hazards. In addition they undermine research and development of radiation technology and tend to subjugate science and the quest for understanding nature to phobic practices.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hassan, Nur Nazihah; Khoo, Kok Siong
Pengerang area consists of a mix of private plantation, individual residential lots and state land, which is leased for agriculture related activities. The analysis was conducted to determine the specific activity of the initial value and the radiation hazard indices in the surrounding area in Pengerang. This area will be developed into a major downstream for oil and gas. The aims of this preliminary study were 1) to determine the specific activities of {sup 238}U, {sup 232}Th, {sup 226}Ra and {sup 40}K of soil samples at six selected areas by Gamma-ray spectrometry and 2) to calculate the radiation hazard indices.more » The specific activities (Bq/kg) of the samples ranged from 7.08±5.01 to 36.29±25.72 Bq/kg, 5.62±3.98 to 34.53±24.07 Bq/kg, 4.75±3.42 to 24.76±17.66 Bq/kg and 10.58±7.51 to 101.25±72.00 Bq/kg for {sup 238}U, {sup 232}Th, {sup 226}Ra and {sup 40}K, respectively. These values were well within the range that reported by UNSCEAR. The study also examined the radiation hazard indices, the mean values obtained were 48.49±28.06 Bq/kg for Radium Equivalent Activity (Raeq), 0.34 Bq/kg for Representative Level Index (I{sub γ}), 21.83 nGy/h for Absorbed dose rates (D), 0.27 mSv/y for Annual Effective Dose Rates (Deff), 0.13 and 0.18 for External Hazards Index (H{sub ex}) and Internal Hazard Index (H{sub in}), respectively. These calculated hazard indices were used to estimate the potential radiological health risk in soil and the dose rates associated with it were well below their permissible limit. The overall findings show that no radiological threat to the health of the population in the study area.« less
Lacey, Steven E.; Vesper, Benjamin J.; Paradise, William A.; Radosevich, James A.; Colvard, Michael D.
2013-01-01
Abstract Objective: Photodynamic therapy (PDT) as a medical treatment for cancers is an increasing practice in clinical settings, as new photosensitizing chemicals and light source technologies are developed and applied. PDT involves dosing patients with photosensitizing drugs, and then exposing them to light using a directed energy device in order to manifest a therapeutic effect. Healthcare professionals providing PDT should be aware of potential occupational health and safety hazards posed by these treatment devices and photosensitizing agents administered to patients. Materials and methods: Here we outline and identify pertinent health and safety considerations to be taken by healthcare staff during PDT procedures. Results: Physical hazards (for example, non-ionizing radiation generated by the light-emitting device, with potential for skin and eye exposure) and chemical hazards (including the photosensitizing agents administered to patients that have the potential for exposure via skin, subcutaneous, ingestion, or inhalation routes) must be considered for safe use of PDT by the healthcare professional. Conclusions: Engineering, administrative, and personal protective equipment controls are recommendations for the safe use and handling of PDT agents and light-emitting technologies. PMID:23859750
Control of Hazards to Health From Laser Radiation
2006-01-01
compared to the calculated AEL. (2) Optically aided viewing. Viewing a laser beam with optical aids (other than ordinary eyeglasses or contact lenses ...resonant optical cavity. TB MED 524 8 b. Lenses , mirrors, cooling systems, shutters, and other accessories may be added to the system to obtain...procedures for laser optical systems (for example, mirrors, prisms, and lenses ) that employ Class 2 and Class 3a lasers, it is always good laser safety
ERIC Educational Resources Information Center
Green, Jack N., Ed.
Most of this conference report is made up of papers presented on miscellaneous campus safety topics: two papers titled "Handicapped on Campus," by Charles Wingstrom and by Joseph F. Kuchta, Sal Mazzata, and Charles A. Cofield; "Radiation Hazards and Control" by Howard Browne; "Safety in the 70's" by Harold E. O'Shell; "OSHA (Occupational Safety…
Matthews, Stephen M.; Schonberg, Russell G.; Fadness, David R.
1994-01-01
What is disclosed is a novel toxic waste remediation system designed to provide on-site destruction of a wide variety of hazardous organic volatile hydrocarbons, including but not limited to halogenated and aromatic hydrocarbons in the vapor phase. This invention utilizes a detoxification plenum and radiation treatment which transforms hazardous organic compounds into non-hazardous substances.
Hazard of ultraviolet radiation emitted in gas tungsten arc welding of aluminum alloys.
Nakashima, Hitoshi; Utsunomiya, Akihiro; Fujii, Nobuyuki; Okuno, Tsutomu
2016-01-01
Ultraviolet radiation (UVR) emitted during arc welding frequently causes keratoconjunctivitis and erythema. The extent of the hazard of UVR varies depending on the welding method and conditions. Therefore, it is important to identify the levels of UVR that are present under various conditions. In this study, we experimentally evaluated the hazard of UVR emitted in gas tungsten arc welding (GTAW) of aluminum alloys. The degree of hazard of UVR is measured by the effective irradiance defined in the American Conference of Governmental Industrial Hygienists guidelines. The effective irradiances measured in this study are in the range 0.10-0.91 mW/cm(2) at a distance of 500 mm from the welding arc. The maximum allowable exposure times corresponding to these levels are only 3.3-33 s/day. This demonstrates that unprotected exposure to UVR emitted by GTAW of aluminum alloys is quite hazardous in practice. In addition, we found the following properties of the hazard of UVR. (1) It is more hazardous at higher welding currents than at lower welding currents. (2) It is more hazardous when magnesium is included in the welding materials than when it is not. (3) The hazard depends on the direction of emission from the arc.
Hazard of ultraviolet radiation emitted in gas tungsten arc welding of aluminum alloys
NAKASHIMA, Hitoshi; UTSUNOMIYA, Akihiro; FUJII, Nobuyuki; OKUNO, Tsutomu
2015-01-01
Ultraviolet radiation (UVR) emitted during arc welding frequently causes keratoconjunctivitis and erythema. The extent of the hazard of UVR varies depending on the welding method and conditions. Therefore, it is important to identify the levels of UVR that are present under various conditions. In this study, we experimentally evaluated the hazard of UVR emitted in gas tungsten arc welding (GTAW) of aluminum alloys. The degree of hazard of UVR is measured by the effective irradiance defined in the American Conference of Governmental Industrial Hygienists guidelines. The effective irradiances measured in this study are in the range 0.10–0.91 mW/cm2 at a distance of 500 mm from the welding arc. The maximum allowable exposure times corresponding to these levels are only 3.3–33 s/day. This demonstrates that unprotected exposure to UVR emitted by GTAW of aluminum alloys is quite hazardous in practice. In addition, we found the following properties of the hazard of UVR. (1) It is more hazardous at higher welding currents than at lower welding currents. (2) It is more hazardous when magnesium is included in the welding materials than when it is not. (3) The hazard depends on the direction of emission from the arc. PMID:26632121
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
Materials developed by NIOSH concerning video display terminals (VDTs) comprise the publication. The first section listed citations of reports developed by NIOSH concerning VDTs and possible hazards associated with their use, and contained ordering information for these publications. Types of publications included NIOSH numbered publications, hazard evaluation and technical assistance reports, contract reports, journal articles, book chapters, presentations, and miscellaneous reports. The second section of the report contained full text copies of selected references from the bibliography. These references included testimony before congressional committees, presentations and articles dealing with radiation issues, reproductive outcomes of workers using VDTs the risk ofmore » spontaneous abortion, an epidemiologic investigation of electric and magnetic fields and operator exposure, controlling glare problems in the VDT work environment, and the design of rest breaks for VDT operators.« less
Herbert M. Parker: Publications and other contributions to radiological and health physics
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kathren, R.L.; Baalman, R.W.; Bair, W.J.
For more than a half century, Herbert M. Parker was a leading force in radiological physics. This book brings together all of Parker's published and unpublished papers and is divided into six parts. The second edition is on his work in medical physics. The third part is on his contribution to the evolution of radiological units. The fourth and largest portion of the book is on radiation protection: the Manhattan Project and beyond. There are no less than 31 subsections to this part of the book, and it includes: possible hazards of repeated fluoroscopy in infants, health protection, health physicsmore » implementation and radiation protection, radiation protection in the atomic energy industry, radiation exposure from environmental hazards, personnel dosimetry for radiation accidents, and an article on the dilemma of lung dosimetry.« less
Radiation Hardness Assurance (RHA) for Space Systems
NASA Technical Reports Server (NTRS)
Poivey, Christian; Buchner, Stephen
2007-01-01
This presentation discusses radiation hardness assurance (RHA) for space systems, providing both the programmatic aspects of RHA and the RHA procedure. RHA consists of all activities undertaken to ensure that the electronics and materials of a space system perform to their design specifications after exposure to the space radiation environment. RHA also pertains to environment definition, part selection, part testing, spacecraft layout, radiation tolerant design, and mission/system/subsystems requirements. RHA procedure consists of establishing mission requirements, defining and evaluating the radiation hazard, selecting and categorizing the appropriate parts, and evaluating circuit response to hazard. The RHA approach is based on risk management and is confined only to parts, it includes spacecraft layout, system/subsystem/circuit design, and system requirements and system operations. RHA should be taken into account in the early phases of a program including the proposal and feasibility analysis phases.
NASA Technical Reports Server (NTRS)
Lin, Z. W.; Adams, J. H., Jr.
2006-01-01
The radiation hazard for astronauts from galactic cosmic rays is a major obstacle in long duration human space explorations. Space radiation transport codes have been developed to calculate radiation environment on missions to the Moon, Mars or beyond. We have studied how uncertainties in fragmentation cross sections at different energies affect the accuracy of predictions from such radiation transport. We find that, in deep space, cross sections between 0.3 and 0.85 GeV/u usually have the largest effect on dose-equivalent behind shielding in solar minimum GCR environments, and cross sections between 0.85 and 1.2 GeV/u have the largest effect in solar maximum GCR environments. At the International Space Station, cross sections at higher energies have the largest effect due to the geomagnetic cutoff.
Health-hazard-evaluation report HETA 89-234-2014, Sims Radiator Shop, Decatur, Georgia
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gunter, B.J.; Hales, T.
1990-02-01
In response to a request from the owner, an investigation was undertaken of possible hazardous working conditions at the Sims Radiator Shop (SIC-3714), Decatur, Georgia. The shop employs seven workers, five of whom are mechanics, involved in the cleaning and repairing of automobile and truck radiators. The 8 hour time weighted average lead (7439921) concentrations for four of the mechanics were 50, 30, 20, and 10 micrograms per cubic meter (microg/cu m). One of these was at the OSHA permissible exposure limit of 50microg/cu m. All seven employees participated in a medical evaluation. None of the shop employees had anymore » physical symptoms suggestive of lead intoxication. The authors conclude that a health hazard existed from overexposure to lead. The authors recommend that the provisions of the OSHA lead standard should be implemented to protect the workers.« less
The impact of the new biology on radiation risks in space
NASA Technical Reports Server (NTRS)
Dicello, John F.
2003-01-01
Radiation is considered to be one of three or four major hazards for personnel in space and has emerged as the most critical issue to be resolved for long-term missions, both orbital and interplanetary. Space habitats are stressful and dangerous environments. Health and medical consequences arising from microgravity, stress, and trauma include weakened immune systems, increased viral activity, and loss of bone mass. The greatest risks from radiation are generally assumed to be cancers and possibly damage to the central nervous system. Synergistic effects arising from the other environmental hazards along with abscopal and exogenic factors are likely. Space programs represent an exceptional opportunity for examining the biological consequences of low-dose exposures of humans to radiation at every level of progression. Although astronauts are a relatively small population, they are healthy, physically active volunteers who undergo extensive testing and medical examinations before, during, and after protracted exposures with periodic follow-up examinations. The radiation environments along with other hazards are likewise monitored and documented. Extensive international research programs are in progress. Seven years ago the U.S. National Aeronautics and Space Administration established the National Space Biomedical Research Institute through a cooperative agreement with a consortium of research and academic institutions in order to address radiation issues through a concerted, programmatic effort. Advanced technologies are rapidly being incorporated into these programs to determine the significance of new biological data and to evaluate the interplay among the different medical hazards. Programmatic in vivo and in vitro studies of the processes leading to carcinogenesis are in progress. Drugs and dietary supplements are being examined at the cellular and in vivo levels to assess their potential as dose-modifying agents. The infrastructure of this new approach, recent results, and research in progress are reviewed and discussed.
Gudzenko, Nataliya; Hatch, Maureen; Bazyka, Dimitry; Dyagil, Irina; Reiss, Robert F; Brenner, Alina; Chumak, Vadim; Babkina, Natalie; Zablotska, Lydia B; Mabuchi, Kiyohiko
2015-01-01
Background Occupational and environmental exposure to chemicals such as benzene has been linked to increased risk of leukemia. Cigarette smoking and alcohol consumption have also been found to affect leukemia risk. Previous analyses in a large cohort of Chornobyl clean-up workers in Ukraine found significant radiation-related increased risk for all leukemia types. We investigated the potential for additional effects of occupational and lifestyle factors on leukemia risk in this radiation-exposed cohort. Methods In a case-control study of chronic lymphocytic and other leukemias among Chornobyl cleanup workers, we collected data on a range of non-radiation exposures. We evaluated these other potential risk factors in analyses adjusting for estimated bone marrow radiation dose. We calculated Odds Ratios and 95% Confidence Intervals in relation to lifestyle factors and occupational hazards. Results After adjusting for radiation, we found no clear association of leukemia risk with smoking or alcohol but identified a two-fold elevated risk for non-CLL leukemia with occupational exposure to petroleum (OR=2.28; 95% Confidence Interval 1.13, 6.79). Risks were particularly high for myeloid leukemias. No associations with risk factors other than radiation were found for chronic lymphocytic leukemia. Conclusions These data – the first from a working population in Ukraine – add to evidence from several previous reports of excess leukemia morbidity in groups exposed environmentally or occupationally to petroleum or its products. PMID:26117815
Gudzenko, N; Hatch, M; Bazyka, D; Dyagil, I; Reiss, R F; Brenner, A; Chumak, V; Babkina, N; Zablotska, L B; Mabuchi, K
2015-10-01
Occupational and environmental exposure to chemicals such as benzene has been linked to increased risk of leukemia. Cigarette smoking and alcohol consumption have also been found to affect leukemia risk. Previous analyses in a large cohort of Chornobyl clean-up workers in Ukraine found significant radiation-related increased risk for all leukemia types. We investigated the potential for additional effects of occupational and lifestyle factors on leukemia risk in this radiation-exposed cohort. In a case-control study of chronic lymphocytic and other leukemias among Chornobyl cleanup workers, we collected data on a range of non-radiation exposures. We evaluated these and other potential risk factors in analyses adjusting for estimated bone marrow radiation dose. We calculated Odds Ratios and 95% Confidence Intervals in relation to lifestyle factors and occupational hazards. After adjusting for radiation, we found no clear association of leukemia risk with smoking or alcohol but identified a two-fold elevated risk for non-CLL leukemia with occupational exposure to petroleum (OR=2.28; 95% Confidence Interval 1.13, 6.79). Risks were particularly high for myeloid leukemias. No associations with risk factors other than radiation were found for chronic lymphocytic leukemia. These data - the first from a working population in Ukraine - add to evidence from several previous reports of excess leukemia morbidity in groups exposed environmentally or occupationally to petroleum or its products. Copyright © 2015 Elsevier Inc. All rights reserved.
Toxic Remediation System And Method
Matthews, Stephen M.; Schonberg, Russell G.; Fadness, David R.
1996-07-23
What is disclosed is a novel toxic waste remediation system designed to provide on-site destruction of a wide variety of hazardous organic volatile hydrocarbons, including but not limited to halogenated and aromatic hydrocarbons in the vapor phase. This invention utilizes a detoxification plenum and radiation treatment which transforms hazardous organic compounds into non-hazardous substances.
Of Modeling the Radiation Hazards Along Trajectory Space Vehicles Various Purpose
NASA Astrophysics Data System (ADS)
Grichshenko, Valentina
2016-07-01
The paper discusses the results of the simulation of radiation hazard along trajectory low-orbit spacecraft for various purposes, geostationary and navigation satellites. Developed criteria of reliability of memory cells in Space, including influence of cosmic rays (CR), differences of geophysical and geomagnetic situation on SV orbit are discussed. Numerical value of vertical geomagnetic stiffness, of CR flux and assessment of correlation failures of memory cells along low-orbit spacecrafts trajectory are presented. Obtained results are used to forecasting the radiation situation along SV orbit, reliability of memory cells in the Space and to optimize nominal equipment kit and payload of Kazakhstan SV.
Ionizing and Nonionizing Radiation Protection. Module SH-35. Safety and Health.
ERIC Educational Resources Information Center
Center for Occupational Research and Development, Inc., Waco, TX.
This student module on ionizing and nonionizing radiation protection is one of 50 modules concerned with job safety and health. This module describes various types of ionizing and nonionizing radiation, and the situations in the workplace where potential hazards from radiation may exist. Following the introduction, 13 objectives (each keyed to a…
29 CFR 570.57 - Exposure to radioactive substances and to ionizing radiations (Order 6).
Code of Federal Regulations, 2013 CFR
2013-07-01
... radiations (Order 6). 570.57 Section 570.57 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR... to Their Health or Well-Being § 570.57 Exposure to radioactive substances and to ionizing radiations... radioactive substances and to ionizing radiations are particularly hazardous and detrimental to health for...
29 CFR 570.57 - Exposure to radioactive substances and to ionizing radiations (Order 6).
Code of Federal Regulations, 2014 CFR
2014-07-01
... radiations (Order 6). 570.57 Section 570.57 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR... to Their Health or Well-Being § 570.57 Exposure to radioactive substances and to ionizing radiations... radioactive substances and to ionizing radiations are particularly hazardous and detrimental to health for...
29 CFR 570.57 - Exposure to radioactive substances and to ionizing radiations (Order 6).
Code of Federal Regulations, 2012 CFR
2012-07-01
... radiations (Order 6). 570.57 Section 570.57 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR... to Their Health or Well-Being § 570.57 Exposure to radioactive substances and to ionizing radiations... radioactive substances and to ionizing radiations are particularly hazardous and detrimental to health for...
Polymer-composite materials for radiation protection.
Nambiar, Shruti; Yeow, John T W
2012-11-01
Unwanted exposures to high-energy or ionizing radiation can be hazardous to health. Prolonged or accumulated radiation dosage from either particle-emissions such as alpha/beta, proton, electron, neutron emissions, or high-energy electromagnetic waves such as X-rays/γ rays, may result in carcinogenesis, cell mutations, organ failure, etc. To avoid occupational hazards from these kinds of exposures, researchers have traditionally used heavy metals or their composites to attenuate the radiation. However, protective gear made of heavy metals are not only cumbersome but also are capable of producing more penetrative secondary radiations which requires additional shielding, increasing the cost and the weight factor. Consequently, significant research efforts have been focused toward designing efficient, lightweight, cost-effective, and flexible shielding materials for protection against radiation encountered in various industries (aerospace, hospitals, and nuclear reactors). In this regard, polymer composites have become attractive candidates for developing materials that can be designed to effectively attenuate photon or particle radiation. In this paper, we review the state-of-the-art of polymer composites reinforced with micro/nanomaterials, for their use as radiation shields.
The Geomagnetic Field and Radiation in Near-Earth Orbits
NASA Technical Reports Server (NTRS)
Heirtzler, J. R.
1999-01-01
This report shows, in detail, how the geomagnetic field interacts with the particle flux of the radiation belts to create a hazard to spacecraft and humans in near-Earth orbit. It illustrates the geometry of the geomagnetic field lines, especially around the area where the field strength is anomalously low in the South Atlantic Ocean. It discusses how the field will probably change in the future and the consequences that may have on hazards in near space.
NASA Astrophysics Data System (ADS)
Vysotsky, V. L.; Sivintsev, Yu. V.; Sotnikov, V. A.; Khokhlov, V. N.
2014-12-01
The methodology and results of a weighted average evaluation of the release of man-made radio-nuclides into seawater out of nuclear- and radiation-hazardous objects located on the sea bottom over a long period of time (from dumping/sinking to complete destruction of their structural elements) are presented in the paper. The expected radio-ecological implications of environmental contamination are estimated for the main stages of destruction.
Lead exposure among automobile radiator repair workers and their children in New York City.
Nunez, C M; Klitzman, S; Goodman, A
1993-05-01
Despite a comprehensive Occupational Safety and Health Administration lead standard, exposure to lead continues in many industries. This paper describes a blood lead screening and education program for automobile radiator repair workers and their families in New York City. Results showed that 67% of automobile radiator repair workers (n = 62) in 89% of the shops tested (n = 24) had blood lead levels in excess of 25 micrograms/dl. The vast majority of workers had never been tested previously, and none had received health and safety training regarding occupational lead exposure. Although none of the workers' children's blood lead levels were in excess of then-current guidelines, several had levels which may be associated with subclinical toxicity and in excess of the revised Centers for Disease Control guidelines of 10 micrograms/dl. This project demonstrates that lead exposure in the automotive radiator repair industry continues to be widespread and that local health departments can assist in hazard identification and remediation.
Integrated Satellite Control in REIMEI (INDEX) Satellite
NASA Astrophysics Data System (ADS)
Fukuda, Seisuke; Mizuno, Takahide; Sakai, Shin-Ichiro; Fukushima, Yousuke; Saito, Hirobumi
REIMEI/INDEX (INnovative-technology Demonstration EXperiment) is a 70kg class small satellite which the Institute of Space and Astronautical Science, Japan Exploration Agency, ISAS/JAXA, has developed for observation of auroral small-scale dynamics as well as demonstration of advanced satellite technologies. An important engineering mission of REIMEI is integrated satellite control using commercial RISC CPUs with a triple voting system in order to ensure fault-tolerance against radiation hazards. Software modules concerning every satellite function, such as attitude control, data handling, and mission applications, work cooperatively so that highly sophisticated satellite control can be performed. In this paper, after a concept of the integrated satellite control is introduced, the Integrated Controller Unit (ICU) is described in detail. Also unique topics in developing the integrated control system are shown.
RADIOLOGICAL IMPACTS ASSESSMENT FOR WORKERS IN CERAMIC INDUSTRY IN SERBIA.
Todorovic, Nataša; Mrda, Dušan; Hansman, Jan; Todorovic, Slavko; Nikolov, Jovana; Krmar, Miodrag
2017-11-01
Studies have been carried out to determine the natural radioactivity in some materials used in ceramic industry (zircon, zirkosil, Zircobit MO/S, zircon silicate, zirklonil frit, hematite, bentonite, wollastonite, raw kaolin, kaolinized granite, sileks ball, feldspar, pigment, white base serigraphic, engobe) and their associated radiation hazard. The external hazard index, Hex, values, radium equivalent activity, Raeq, total absorbed dose rates, D and annual effective dose, De were derived for all measured materials and compared with the recommended values to assess the external radiation hazards to workers who worked in ceramic industries in Serbia. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ellis, F
The main hazard to the nursing staff in hospitals where radiotherapy is carried out is in connectlon with the use of Ra. The risk of leukemia or skin cancer to the individual is considered negligible as is the genetic risk. Assuming a gene mutation in each partner of a marriage, the probability that the same gene was changed is about 1 in 4 x 10/sup 1//sup 2/ The protection and instructions to nurses working in the radium ward of the Churchill Hospital, London, is discussed. Organization and procedures carried out in the operating theater and wards are also discussed. (P.C.H.)
[Classification of laser irradiation and safety measures].
Takac, S; Stojanović, S
1998-01-01
The use of lasers in medicine and especially surgery is rapidly expanding in many disciplines from clinical laboratory to the office practice and operating room. It is essential that users of this powerful tool have knowledge of their potential hazards and the measures to protect patients and personnel against injuries or undesired effects. Below, we have included information about the way lasers are classified; the development of protective standards; the current status of protection standards that apply to lasers, especially those used in medicine/surgery; the specific kinds of hazards associated with medical/surgical applications; and the measures by which hazards have been controlled. Since laser technology is still a young field, it is likely that problems unknown at present will occur and methodologies for controlling hazards will evolve. The American National Standards Committee produced the first consensus standard Z136.1 in 1973. The Standard was revised in 1976 to accommodate differences in biological effects for different wavelengths in the visible spectrum. The ANSI Standard has been revised again in 1980, and currently (1984) there are two additional standards in preparation, Z136.2 and 136.3, which treat the safe use of light-emitting diodes and the safe use of lasers in the health care environment, respectively. Most surgical and medical lasers are Class III or IV. Some lasers have a Class IV therapy level beam plus a Class I or II alignment beam. When using lasers, it is possible to generate incandescence or fluorescence in an irradiated object. This can occur even with protective eyewear, because the correlated radiations are usually of a different wavelength. Generally, this should not be a problem when beams are directed at biological material. However, hazard could be caused by lasers designed to produce fluorescence. Control of correlative radiation in a laser system is required in the federal regulations. Hazards of lasers may be grouped as those to the eye, skin and associated hazards, fire, x-rays, electrical, fumes, toxic materials, etc. Effects on tissue are governed by the following factors:--the energy or power density of the beam;--the absorption in tissue at the laser wavelength;--the time the beam is held at a given area.;--the protective effects of heat removal by thermal conduction and by circulation. Eye hazards include thermal burns or acoustical disruption (shock waves) from high-powered or high-energy beams in the visible and near infrared wavelengths. Direct beam exposure or specular or diffuse reflaction from these very high-power lasers can also cause injuries to other parts of the retina. For example, beams can directly penetrate through the sclera and cause retinal injury. Near ultraviolet (less than 400 hm) and far infrared (.3000 hm including CO2 lasers) can cause moderate to severe corneal burns. Far ultraviolet (200-315 nm), mid infrared (1400-3000 nanometers) can cause welders' flash or snow blindness and chronic exposure could cause cataract, and exposure to ultraviolet rays may be carcinogenic. For CO2 lasers, the far infrared radiation is attenuated by plastic goggles, or by glasses, or quartz. Other eyewear with special filters is used for different lasers. The whole personnel who may be exposed to direct beams, specular reflections, and many times diffuse reflections must wear protective eyewear. In all cases the surgeon and others viewing the procedure through the endoscope need glasses or suitable protective lenses installed in the endoscope. Persons who are not viewing the beam may not need to wear protective glasses with the same level of optical density. Glasses may be selected to provide protection for lasers operating in the visible wavelength to the point where the normal aversion response could protect the individual.
Paternal influences on pregnancy complications and birth outcomes
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cleghorn de Rohrmoser, D.C.
1992-01-01
The purpose of this study was to investigate the relationship of selected characteristics of the paternal work environment and occupational history to the incidence of complications in pregnancy, complications in labor and anomalies in birth outcomes. The literature suggested that male exposure to teratogenic hazards in the form of radiation and chemical compounds, primarily in the form of solvents, has been implicated in reproductive disorders and malformed offspring in animals. Similarly, some recent research suggests that the exposure of male workers to such hazards on their job may have consequences for their spouses and children. Based on these experimental researchmore » studies and analyses of persons working in high risk occupations, a broader study of the potential contribution of paternal work environment variables to the success of pregnancy and birth outcomes seemed warranted. Based upon the literature review, a model was proposed for predicting complications in pregnancy, complications in labor and birth outcome (normal birth, low birth weight, congenital malformations and fetal death). From the 1980 National Natality Survey and the 1980 National Fetal Mortality Survey, four sub-samples of married couples, with both husband and wife employed, were selected on the basis of one of the four birth outcomes. The model called for controlling a range of maternal intrinsic and extrinsic health and behavioral variables known to be related to birth outcomes. Multiple logistic regression procedures were used to analyze the effects of father's exposure to radiation and solvents on the job, to complications in pregnancy and labor, and to birth outcome, while controlling for maternal variables. The results indicated that none of the paternal variables were predictors of complications in labor. Further, there was no clear pattern of results, though father's degree of exposure to solvents, and exposures to radiation did reach significance in some analyses.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chen, Allen M.; Granchi, Phillip J.; Garcia, Joaquin
2007-03-15
Purpose: To determine factors predictive of local-regional recurrence (LRR) after surgery alone for carcinomas of the major salivary glands in an attempt to evaluate the potential role of postoperative radiation therapy. Methods and Materials: Between 1960 and 2004, 207 patients with carcinomas of the major salivary glands were treated with definitive surgery without postoperative radiation therapy. Histology was: 67 mucoepidermoid (32%), 50 adenoid cystic (24%), 34 acinic cell (16%), 23 malignant mixed (11%), 16 adenocarcinoma (8%), 6 oncocytic (3%), 6 myoepithelial (3%), and 5 other (2%). Distribution of pathologic T-stage was: 54 T1 (26%), 83 T2 (40%), 46 T3 (22%),more » and 24 T4 (12%). Sixty patients (29%) had microscopically positive margins. Median follow-up was 6.1 years (range, 0.5-18.7 years). Results: The 5-year and 10-year estimates of local-regional control were 86% and 74%, respectively. A Cox proportional hazard model identified pathologic lymph node metastasis (hazard ratio [HR], 4.8; p = 0.001), high histologic grade (HR, 4.2; p = 0.003), positive margins (HR, 2.6; p = 0.03), and T3-4 disease (HR, 2.0; p = 0.04) as independent predictors of LRR. The presence of any one of these factors was associated with 10-year local-regional control rates of 37% to 63%. Conclusion: Lymph node metastasis, high tumor grade, positive margins, and T3-4 stage predict for significant rates of LRR after surgery for carcinomas of the major salivary glands. Postoperative radiation therapy should be considered for patients with these disease characteristics.« less
Allegra, Carmen J; Yothers, Greg; O'Connell, Michael J; Beart, Robert W; Wozniak, Timothy F; Pitot, Henry C; Shields, Anthony F; Landry, Jerome C; Ryan, David P; Arora, Amit; Evans, Lisa S; Bahary, Nathan; Soori, Gamini; Eakle, Janice F; Robertson, John M; Moore, Dennis F; Mullane, Michael R; Marchello, Benjamin T; Ward, Patrick J; Sharif, Saima; Roh, Mark S; Wolmark, Norman
2015-11-01
National Surgical Adjuvant Breast and Bowel Project R-04 was designed to determine whether the oral fluoropyrimidine capecitabine could be substituted for continuous infusion 5-FU in the curative setting of stage II/III rectal cancer during neoadjuvant radiation therapy and whether the addition of oxaliplatin could further enhance the activity of fluoropyrimidine-sensitized radiation. Patients with clinical stage II or III rectal cancer undergoing preoperative radiation were randomly assigned to one of four chemotherapy regimens in a 2x2 design: CVI 5-FU or oral capecitabine with or without oxaliplatin. The primary endpoint was local-regional tumor control. Time-to-event endpoint distributions were estimated using the Kaplan-Meier method. Hazard ratios were estimated from Cox proportional hazard models. All statistical tests were two-sided. Among 1608 randomized patients there were no statistically significant differences between regimens using 5-FU vs capecitabine in three-year local-regional tumor event rates (11.2% vs 11.8%), 5-year DFS (66.4% vs 67.7%), or 5-year OS (79.9% vs 80.8%); or for oxaliplatin vs no oxaliplatin for the three endpoints of local-regional events, DFS, and OS (11.2% vs 12.1%, 69.2% vs 64.2%, and 81.3% vs 79.0%). The addition of oxaliplatin was associated with statistically significantly more overall and grade 3-4 diarrhea (P < .0001). Three-year rates of local-regional recurrence among patients who underwent R0 resection ranged from 3.1 to 5.1% depending on the study arm. Continuous infusion 5-FU produced outcomes for local-regional control, DFS, and OS similar to those obtained with oral capecitabine combined with radiation. This study establishes capecitabine as a standard of care in the pre-operative rectal setting. Oxaliplatin did not improve the local-regional failure rate, DFS, or OS for any patient risk group but did add considerable toxicity. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.
Data acquisition and analysis of range-finding systems for spacing construction
NASA Technical Reports Server (NTRS)
Shen, C. N.
1981-01-01
For space missions of future, completely autonomous robotic machines will be required to free astronauts from routine chores of equipment maintenance, servicing of faulty systems, etc. and to extend human capabilities in hazardous environments full of cosmic and other harmful radiations. In places of high radiation and uncontrollable ambient illuminations, T.V. camera based vision systems cannot work effectively. However, a vision system utilizing directly measured range information with a time of flight laser rangefinder, can successfully operate under these environments. Such a system will be independent of proper illumination conditions and the interfering effects of intense radiation of all kinds will be eliminated by the tuned input of the laser instrument. Processing the range data according to certain decision, stochastic estimation and heuristic schemes, the laser based vision system will recognize known objects and thus provide sufficient information to the robot's control system which can develop strategies for various objectives.
Will radiation control be by reason or regulation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Taylor, L.S.
1988-08-01
Following a very brief review of the development of our present radiation-protection philosophy, attention is directed to what the author sees as current problems. The only prognostication will be that at least certain of the problems outstanding or developing today will be among those that will have to be addressed in the coming four decades. For the past six decades, the major effort has been the development of the science and philosophy of radiation biology and its application to protection against radiation hazards, whether real or imagined. For three decades there has been public concern about radiation generally, the coremore » of the problem being inadequate education of the public and the media on the subject. For a little over one decade, there has been rapidly developing growth of tort litigation generally, involving ionizing radiation in particular. These are the three major lines of attention in the radiation-protection area today; between two of them there are already some of the aspects of the arena. Behind all three lies an overwhelming lack of understanding by, and education of, the public, which shows mostly in the public fetish for absolute safety which, of course, cannot be. These must be the major concerns of the radiation-protection community in the coming four decades.« less
Ravisankar, R; Vanasundari, K; Chandrasekaran, A; Rajalakshmi, A; Suganya, M; Vijayagopal, P; Meenakshisundaram, V
2012-04-01
The natural level of radioactivity in building materials is one of the major causes of external exposure to γ-rays. The primordial radionuclides in building materials are one of the sources of radiation hazard in dwellings made of these materials. By the determination of the radioactivity level in building materials, the indoor radiological hazard to human health can be assessed. This is an important precautionary measure whenever the dose rate is found to be above the recommended limits. The aim of this work was to measure the specific activity concentration of (226)Ra, (232)Th and (40)K in commonly used building materials from Namakkal, Tamil Nadu, India, using gamma-ray spectrometer. The radiation hazard due to the total natural radioactivity in the studied building materials was estimated by different approaches. The concentrations of the natural radionuclides and the radium equivalent activity in studied samples were compared with the corresponding results of different countries. From the analysis, it is found that these materials may be safely used as construction materials and do not pose significant radiation hazards. Copyright © 2011 Elsevier Ltd. All rights reserved.
Occupational hazards to hospital personnel
DOE Office of Scientific and Technical Information (OSTI.GOV)
Patterson, W.B.; Craven, D.E.; Schwartz, D.A.
1985-05-01
Hospital personnel are subject to various occupational hazards. Awareness of these risks, compliance with basic preventive measures, and adequate resources for interventions are essential components of an occupational health program. Physical, chemical, and radiation hazards; important infectious risks; and psychosocial problems prevalent in hospital workers are reviewed. A rational approach to managing and preventing these problems is offered. 370 references.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gudzenko, N., E-mail: gudznat@gmail.com; Hatch, M., E-mail: hatchm@mail.nih.gov; Bazyka, D., E-mail: Bazyka@yahoo.com
Background: Occupational and environmental exposure to chemicals such as benzene has been linked to increased risk of leukemia. Cigarette smoking and alcohol consumption have also been found to affect leukemia risk. Previous analyses in a large cohort of Chornobyl clean-up workers in Ukraine found significant radiation-related increased risk for all leukemia types. We investigated the potential for additional effects of occupational and lifestyle factors on leukemia risk in this radiation-exposed cohort. Methods: In a case-control study of chronic lymphocytic and other leukemias among Chornobyl cleanup workers, we collected data on a range of non-radiation exposures. We evaluated these and othermore » potential risk factors in analyses adjusting for estimated bone marrow radiation dose. We calculated Odds Ratios and 95% Confidence Intervals in relation to lifestyle factors and occupational hazards. Results: After adjusting for radiation, we found no clear association of leukemia risk with smoking or alcohol but identified a two-fold elevated risk for non-CLL leukemia with occupational exposure to petroleum (OR=2.28; 95% Confidence Interval 1.13, 6.79). Risks were particularly high for myeloid leukemias. No associations with risk factors other than radiation were found for chronic lymphocytic leukemia. Conclusions: These data – the first from a working population in Ukraine – add to evidence from several previous reports of excess leukemia morbidity in groups exposed environmentally or occupationally to petroleum or its products. - Highlights: • A unique population – a cohort of 110,645 Chernobyl clean-up workers from Ukraine. • Followed 1986–2006 for leukemia, interviewed about non-radiation risk factors. • Petroleum exposure increased risk for non-CLL leukemias, particularly CML. • No risk factor other than radiation was found for CLL.« less
Orme, Nicholas M; Rihal, Charanjit S; Gulati, Rajiv; Holmes, David R; Lennon, Ryan J; Lewis, Bradley R; McPhail, Ian R; Thielen, Kent R; Pislaru, Sorin V; Sandhu, Gurpreet S; Singh, Mandeep
2015-03-03
The occupational hazards of working in the interventional laboratory have been inadequately studied for physicians and remain unaddressed for nonphysician personnel. This study sought to determine whether the prevalence of work-related musculoskeletal pain, cancer, and other medical conditions is higher among physicians and allied staff who work in interventional laboratories compared with employees who do not. Mayo Clinic employees who work in affiliated hospitals with interventional cardiology or interventional radiology laboratories took an electronic survey. Results were stratified on the basis of self-reported occupational exposure to procedures that involve radiation. There were 1,543 employees (mean age 43 ± 11.3 years, 33% male) who responded to the survey (response rate of 57%), and 1,042 (67.5%) reported being involved with procedures utilizing radiation. These employees reported experiencing work-related pain more often than the control group before (54.7% vs. 44.7%; p < 0.001) and after adjustment for age, sex, body mass index, pre-existing musculoskeletal conditions, years in profession, and job description (odds ratio: 1.67; 95% confidence interval: 1.32 to 2.11; p < 0.001). Musculoskeletal pain varied significantly by job description, with the highest incidence reported by technicians (62%) and nurses (60%) followed by attending physicians (44%) and trainees (19%; p < 0.001). There was no difference in cancer prevalence between groups (9% vs. 9%; p = 0.96). Musculoskeletal pain is more common among healthcare workers who participate in interventional procedures and is highest in nonphysician employees. The diagnosis of cancer in employees who participate in procedures that utilize radiation was not elevated when compared to controls within the same departments, although any conclusion regarding causality is limited by the cross-sectional nature of the study, as well as the low overall prevalence of malignancy in our study group. Copyright © 2015 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.
Planning Guidance for Response to a Nuclear Detonation
2009-01-16
Radiation and Fallout One of the primary outputs from a nuclear explosion is radiation . Intense radiation is...dose rates based on the quantity of visible fallout. Therefore, visible fallout may possibly be used as an indicator of a direct radiation hazard...to survivors and response workers.15 The National Council on Radiation Protection and Measurements (NCRP) has recommended 10 R/hour (R/hour) as a
Living with Radiation. The Problems of the Nuclear Age for the Layman.
ERIC Educational Resources Information Center
Brannigan, Francis L.
The text takes a practical approach to the understanding of industrial radiation hazards. It is intended for the layman who requires a basic understanding of the relationship of radiation problems to his own field. Discussion includes such topics as: uses which benefit mankind; radiation energy versus fission energy; effects of excessive radiation…
ERIC Educational Resources Information Center
National Council on Radiation Protection and Measurements, Washington, DC.
The problems involved when radiation-producing devices of our contemporary technology are used in the teaching of science at the high school and undergraduate college level are discussed. Information is provided on the hazards involved in the use of radiation-producing equipment or radioactive materials in science demonstrations and experiments…
Radiation Belt and Plasma Model Requirements
NASA Technical Reports Server (NTRS)
Barth, Janet L.
2005-01-01
Contents include the following: Radiation belt and plasma model environment. Environment hazards for systems and humans. Need for new models. How models are used. Model requirements. How can space weather community help?
DOE Office of Scientific and Technical Information (OSTI.GOV)
Higgins, Kristin A., E-mail: kristin.higgins@emory.edu; Winship Cancer Institute, Emory University, Atlanta, Georgia; O'Connell, Kelli
Purpose: To analyze outcomes and predictors associated with proton radiation therapy for non-small cell lung cancer (NSCLC) in the National Cancer Database. Methods and Materials: The National Cancer Database was queried to capture patients with stage I-IV NSCLC treated with thoracic radiation from 2004 to 2012. A logistic regression model was used to determine the predictors for utilization of proton radiation therapy. The univariate and multivariable association with overall survival were assessed by Cox proportional hazards models along with log–rank tests. A propensity score matching method was implemented to balance baseline covariates and eliminate selection bias. Results: A total of 243,822more » patients (photon radiation therapy: 243,474; proton radiation therapy: 348) were included in the analysis. Patients in a ZIP code with a median income of <$46,000 per year were less likely to receive proton treatment, with the income cohort of $30,000 to $35,999 least likely to receive proton therapy (odds ratio 0.63 [95% confidence interval (CI) 0.44-0.90]; P=.011). On multivariate analysis of all patients, non-proton therapy was associated with significantly worse survival compared with proton therapy (hazard ratio 1.21 [95% CI 1.06-1.39]; P<.01). On propensity matched analysis, proton radiation therapy (n=309) was associated with better 5-year overall survival compared with non-proton radiation therapy (n=1549), 22% versus 16% (P=.025). For stage II and III patients, non-proton radiation therapy was associated with worse survival compared with proton radiation therapy (hazard ratio 1.35 [95% CI 1.10-1.64], P<.01). Conclusions: Thoracic radiation with protons is associated with better survival in this retrospective analysis; further validation in the randomized setting is needed to account for any imbalances in patient characteristics, including positron emission tomography–computed tomography staging.« less
Marine disposal of radioactive wastes
NASA Astrophysics Data System (ADS)
Woodhead, D. S.
1980-03-01
In a general sense, the main attraction of the marine environment as a repository for the wastes generated by human activities lies in the degree of dispersion and dilution which is readily attainable. However, the capacity of the oceans to receive wastes without unacceptable consequences is clearly finite and this is even more true of localized marine environments such as estuaries, coastal waters and semi-enclosed seas. Radionuclides have always been present in the marine environment and marine organisms and humans consuming marine foodstuffs have always been exposed, to some degree, to radiation from this source. The hazard associated with ionizing radiations is dependent upon the absorption of energy from the radiation field within some biological entity. Thus any disposal of radioactive wastes into the marine environment has consequences, the acceptability of which must be assessed in terms of the possible resultant increase in radiation exposure of human and aquatic populations. In the United Kingdom the primary consideration has been and remains the safe-guarding of public health. The control procedures are therefore designed to minimize as far as practicable the degree of human exposure within the overall limits recommended as acceptable by the International Commission on Radiological Protection. There are several approaches through which control could be exercised and the strengths and weaknesses of each are considered. In this review the detailed application of the critical path technique to the control of the discharge into the north-east Irish Sea from the fuel reprocessing plant at Windscale is given as a practical example. It will be further demonstrated that when human exposure is controlled in this way no significant risk attaches to the increased radiation exposure experienced by populations of marine organisms in the area.
Standardisation of radiation portal monitor controls and readouts.
Tinker, M
2010-10-01
There is an urgent need to standardise the numbering configuration of radiation portal monitor sensing panels. Currently, manufacturers use conflicting numbering schemes that may confuse operators of these varied systems. There is a similar problem encountered with the varied choices of coloured indicator lights and coloured print lines designated for gamma and neutron alarms. In addition, second-party software that changes the alarm colour scheme may also have been installed. Furthermore, no provision exists for the colour blind or to provide work stations with only black ink on alarm printouts. These inconsistencies and confusing set-ups could inadvertently cause a misinterpretation of the alarm, resulting in the potential release of a radiological hazard into a sovereign country. These issues are discussed, and a proposed solution is offered.
Modeling of Lunar Dust Contamination Due to Plume Impingement
NASA Technical Reports Server (NTRS)
Woronowicz, Michael
2009-01-01
During the Apollo missions it became apparent that lunar dust was a significant hazard. Problems included: surface obscuration during landing sequence; abrasion damage to gouge faces and helmet visors; mechanism clogging; development of space suit pressurization leaks; loss of radiator heat rejection capabilities to the point where vulnerable equipment exceeded maximum survival temperature ratings; temporary vision and respiratory problems within the Apollo Lunar Module (LM). NASA Constellation Program features many system-level components, including the Altair Lunar Lander. Altair to endure longer periods at lunar surface conditions: Apollo LM, about three days; Altair, over seven months. Program managers interested in plume-generated dust transport onto thermal control surface radiators of the first Altair created by its own landing operations.
van Hazel, Guy A; Heinemann, Volker; Sharma, Navesh K; Findlay, Michael P N; Ricke, Jens; Peeters, Marc; Perez, David; Robinson, Bridget A; Strickland, Andrew H; Ferguson, Tom; Rodríguez, Javier; Kröning, Hendrik; Wolf, Ido; Ganju, Vinod; Walpole, Euan; Boucher, Eveline; Tichler, Thomas; Shacham-Shmueli, Einat; Powell, Alex; Eliadis, Paul; Isaacs, Richard; Price, David; Moeslein, Fred; Taieb, Julien; Bower, Geoff; Gebski, Val; Van Buskirk, Mark; Cade, David N; Thurston, Kenneth; Gibbs, Peter
2016-05-20
SIRFLOX was a randomized, multicenter trial designed to assess the efficacy and safety of adding selective internal radiation therapy (SIRT) using yttrium-90 resin microspheres to standard fluorouracil, leucovorin, and oxaliplatin (FOLFOX)-based chemotherapy in patients with previously untreated metastatic colorectal cancer. Chemotherapy-naïve patients with liver metastases plus or minus limited extrahepatic metastases were randomly assigned to receive either modified FOLFOX (mFOLFOX6; control) or mFOLFOX6 plus SIRT (SIRT) plus or minus bevacizumab. The primary end point was progression-free survival (PFS) at any site as assessed by independent centralized radiology review blinded to study arm. Between October 2006 and April 2013, 530 patients were randomly assigned to treatment (control, 263; SIRT, 267). Median PFS at any site was 10.2 v 10.7 months in control versus SIRT (hazard ratio, 0.93; 95% CI, 0.77 to 1.12; P = .43). Median PFS in the liver by competing risk analysis was 12.6 v 20.5 months in control versus SIRT (hazard ratio, 0.69; 95% CI, 0.55 to 0.90; P = .002). Objective response rates (ORRs) at any site were similar (68.1% v 76.4% in control v SIRT; P = .113). ORR in the liver was improved with the addition of SIRT (68.8% v 78.7% in control v SIRT; P = .042). Grade ≥ 3 adverse events, including recognized SIRT-related effects, were reported in 73.4% and 85.4% of patients in control versus SIRT. The addition of SIRT to FOLFOX-based first-line chemotherapy in patients with liver-dominant or liver-only metastatic colorectal cancer did not improve PFS at any site but significantly delayed disease progression in the liver. The safety profile was as expected and was consistent with previous studies. © 2016 by American Society of Clinical Oncology.
Cataractogenic potential of ionizing radiations in animal models that simulate man
NASA Technical Reports Server (NTRS)
Lett, J. T.; Cox, A. B.; Lee, A. C.
1986-01-01
Aspects of experiments on radiation-induced lenticular opacification during the life spans of two animal models, the New Zealand white rabbit and the rhesus monkey, are compared and contrasted with published results from a life-span study of another animal model, the beagle dog, and the most recent data from the ongoing study of the survivors from radiation exposure at Hiroshima and Nagasaki. An important connection among the three animal studies is that all the measurements of cataract indices were made by one of the authors (Lee), so variation from personal subjectivity was reduced to a minimum. The primary objective of the rabbit experiments (radiations involved: Fe-56, Ar-40, and Ne-20 ions and Co-60 gamma photons) is an evaluation of hazards to astronauts from Galactic particulate radiations. An analogous evaluation of hazards from solar flares during space flight is being made with monkeys exposed to 32, 55, 138 and 400-MeV protons. Conclusions are drawn about the proper use of animal models to simulate radiation responses in man and the levels of radiation-induced lenticular opacification that pose risks to man in space.
46 CFR 72.20-50 - Heating and cooling.
Code of Federal Regulations, 2010 CFR
2010-10-01
... operating conditions without curtailing ventilation. (c) Radiators and other heating apparatus must be so... leading to radiators or heating apparatus must be insulated where those pipes create a hazard to persons...
Measurement and standardization of eye safety for optical radiation of LED products
NASA Astrophysics Data System (ADS)
Mou, Tongsheng; Peng, Zhenjian
2013-06-01
The blue light hazard (BLH) to human eye's retina is now a new issue emerging in applications of artificial light sources. Especially for solid state lighting sources based on the blue chip-LED(GaN), the photons with their energy more than 2.4 eV show photochemical effects on the retina significantly, raising damage both in photoreceptors and retinal pigment epithelium. The photobiological safety of artificial light sources emitting optical radiation has gained more and more attention worldwide and addressed by international standards IEC 62471-2006(CIE S009/E: 2002). Meanwhile, it is involved in IEC safety specifications of LED lighting products and covered by European Directive 2006/25/EC on the minimum health and safety requirements regarding the exposure of the workers to artificial optical radiation. In practical applications of the safety standards, the measuring methods of optical radiation from LED products to eyes are important in establishment of executable methods in the industry. In 2011, a new project to develop the international standard of IEC TR62471-4,that is "Measuring methods of optical radiation related to photobiological safety", was approved and are now under way. This paper presents the concerned methods for the assessment of optical radiation hazards in the standards. Furthermore, a retina radiance meter simulating eye's optical geometry is also described, which is a potential tool for blue light hazard assessment of retinal exposure to optical radiation. The spectroradiometric method integrated with charge-coupled device(CCD) imaging system is introduced to provide more reliable results.
Code of Federal Regulations, 2014 CFR
2014-07-01
... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS HEALTH... substantial present or potential hazard to human health and the environment as long as the alternate... potential hazard to human health and the environment of alternate concentration limits, the following...
Gestal, J J
1987-01-01
Except for infectious diseases all the main occupational hazards affecting health workers are reviewed: accidents (explosions, fires, electrical accidents, and other sources of injury); radiation (stochastic and non-stochastic effects, protective measures, and personnel most at risk); exposure to noxious chemicals, whose effects may be either local (allergic eczema) or generalised (cancer, mutations), particular attention being paid to the hazards presented by formol, ethylene oxide, cytostatics, and anaesthetic gases; drug addiction (which is more common among health workers than the general population) and psychic problems associated with promotion, shift work, and emotional stress; and assault (various types of assault suffered by health workers, its causes, and the characterisation of the most aggressive patients). PMID:3307896
Pressure Systems Energy Release Protection (Gas Pressurized Systems)
NASA Technical Reports Server (NTRS)
Brown, S. J. (Editor)
1986-01-01
A survey of studies into hazards associated with closed or pressurized system rupture and preliminary guidelines for the performance design of primary, secondary, and protective receptors of these hazards are provided. The hazards discussed in the survey are: blast, fragments, ground motion, heat radiation, biological, and chemical. Performance guidelines for receptors are limited to pressurized systems that contain inert gas. The performance guidelines for protection against the remaining unaddressed degenerative hazards are to be covered in another study.
NASA Astrophysics Data System (ADS)
Zhang, Jingjing; Guo, Weihong; Xie, Bin; Yu, Xingjian; Luo, Xiaobing; Zhang, Tao; Yu, Zhihua; Wang, Hong; Jin, Xing
2017-09-01
Blue light hazard of white light-emitting diodes (LED) is a hidden risk for human's photobiological safety. Recent spectral optimization methods focus on maximizing luminous efficacy and improving color performances of LEDs, but few of them take blue hazard into account. Therefore, for healthy lighting, it's urgent to propose a spectral optimization method for white LED source to exhibit low blue light hazard, high luminous efficacy of radiation (LER) and high color performances. In this study, a genetic algorithm with penalty functions was proposed for realizing white spectra with low blue hazard, maximal LER and high color rendering index (CRI) values. By simulations, white spectra from LEDs with low blue hazard, high LER (≥297 lm/W) and high CRI (≥90) were achieved at different correlated color temperatures (CCTs) from 2013 K to 7845 K. Thus, the spectral optimization method can be used for guiding the fabrication of LED sources in line with photobiological safety. It is also found that the maximum permissible exposure duration of the optimized spectra increases by 14.9% than that of bichromatic phosphor-converted LEDs with equal CCT.
Wang, Wei-Hsung; McGlothlin, James D; Smith, Deborah J; Matthews, Kenneth L
2006-02-01
This project incorporates radiation survey training into a real-time video radiation detection system, thus providing a practical perspective for the radiation worker on efficient performance of radiation surveys. Regular surveys to evaluate radiation levels are necessary not only to recognize potential radiological hazards but also to keep the radiation exposure as low as reasonably achievable. By developing and implementing an instructional learning system using a real-time radiation survey training video showing specific categorization of work elements, radiation workers trained with this system demonstrated better radiation survey practice.
Abdul-Aziz, Karolin Kamel; Tuorkey, M J
2010-04-02
The ionizing radiations could be taken in considerate as an integral part in our life, since, living organisms are actually exposed to a constant shower of ionizing radiations whether from the natural or artificial resources. The radio-protective efficiency of several chemicals has been confirmed in animal trails, whereas, due to their accumulative toxicity, their clinical utility is limited. Therefore, we aimed in the present work to investigate the possibility of using argon laser to recuperate the damaged tissues due to exposing to the ionizing radiation. The rabbits were used in this study, and they were designed as control, gamma irradiated, laser, and gamma plus laser groups. Lipid peroxidation, reduced glutathione (GSH), glutathione peroxidase (GSH-Px) and glucose-6-phosphate dehydrogenase (G-6-PD) in blood and liver were evaluated. As well as, the level of protein thiol was evaluated in the plasma among each group. Results of this study revealed the potential therapeutic performance of the treatment by laser argon to decline the damaging effect of the ionized radiation whether at systematic or local levels. In conclusion, argon laser therapy appears propitious protective effect against the hazard effects of gamma radiation. Copyright 2010 Elsevier B.V. All rights reserved.
Future Radiation Damage in Space due to South Atlantic Anomaly
NASA Technical Reports Server (NTRS)
Heirtzler, J. R.
1999-01-01
Predictions of radiation damage for Low Earth Orbit (LEO) satellites now use semi-empirical models developed from prior satellite data. From these models it is clear that the low field strength of the South Atlantic Anomaly (SAA) controls where the maximum radiation damage occurs. One may make an estimate of future radiation damage to LEO spacecraft if one can predict the future of the SAA. Although reliable maps of the geomagnetic field strength and its secular change have only been made in the last few decades, certain geomagnetic observatories in South America and Africa have recorded the geomagnetic field for a much longer time. These observatories show that the present geomagnetic field change has persisted for more than 100 years. In spite of the fact that a few observatories have shown sudden changes in secular variation, those around the SAA have shown a stable secular variation. Assuming that this will continue for the next 50 to 100 years one can show that the SAA will expand to cover most of the South Atlantic Ocean and will become much weaker. This will greatly intensify the radiation hazard in LEO, put significant new limitations on radiation-hardened hardware, severely restrict the length of time that humans can remain in orbit, and materially change the configuration of the radiation belts.
Miller, Benjamin J; Gao, Yubo; Duchman, Kyle R
2017-09-01
There is continuing debate regarding the ideal modality for local control of the primary tumor for patients with Ewing's sarcoma. The primary aim of this study is to investigate the impact of the method of local control on overall survival in patients with Ewing's sarcoma. The National Cancer Data Base was used to identify patients <40 years of age with high-grade Ewing's sarcoma of bone. A Kaplan-Meier survival analysis was performed at 2, 5, and 10 years. Factors with a level of significance of P < 0.1 at the 5-year time point were included in a multivariate Cox proportional hazards model. Diminished 5-year survival was noted for patients with metastatic disease, local control with radiation alone, age ≥18 years, tumor size >8 cm, and male sex while controlling for tumor site. Surgery alone was consistently the method of local control that resulted in the highest overall survival. Surgery alone resulted in the best overall survival for patients with Ewing's sarcoma of bone. The results of this investigation provide support to the approach of surgical resection with negative margins when possible. © 2017 Wiley Periodicals, Inc.
Association of Time between Surgery and Adjuvant Therapy with Survival in Oral Cavity Cancer.
Chen, Michelle M; Harris, Jeremy P; Orosco, Ryan K; Sirjani, Davud; Hara, Wendy; Divi, Vasu
2018-06-01
Objective The National Cancer Center Network recommends starting radiation therapy within 6 weeks after surgery for oral cavity squamous cell carcinoma (OCSCC), but there is limited evidence of the importance of the total time from surgery to completion of radiation therapy (package time). We set out to determine if there was an association between package time and survival in OCSCC and to evaluate the impact of treatment location on outcomes. Study Design Retrospective cohort study. Setting Tertiary academic medical center. Subjects and Methods We reviewed the records of patients with OCSCC who completed postoperative radiation therapy at an academic medical center from 2008 to 2016. The primary endpoints were overall survival and recurrence-free survival. Statistical analysis included χ 2 tests and Cox proportional hazards regressions. Results We identified 132 patients with an average package time of 12.6 weeks. On multivariate analysis, package time >11 weeks was independently associated with decreased overall survival (hazard ratio, 6.68; 95% CI, 1.42-31.44) and recurrence-free survival (hazard ratio, 2.94; 95% CI, 1.20-7.18). Patients who received radiation therapy at outside facilities were more likely to have treatment delays (90.2% vs 62.9%, P = .001). Conclusions Prolonged package times are associated with decreased overall and recurrence-free survival among patients with OCSCC. Patients who received radiation therapy at outside facilities are more likely to have prolonged package times.
Thomas, Brian C; Goracke, Byron D
2016-01-01
Astrophysical ionizing radiation events such as supernovae, gamma-ray bursts, and solar proton events have been recognized as a potential threat to life on Earth, primarily through depletion of stratospheric ozone and subsequent increase in solar UV radiation at Earth's surface and in the upper levels of the ocean. Other work has also considered the potential impact of nitric acid rainout, concluding that no significant threat is likely. Not yet studied to date is the potential impact of ozone produced in the lower atmosphere following an ionizing radiation event. Ozone is a known irritant to organisms on land and in water and therefore may be a significant additional hazard. Using previously completed atmospheric chemistry modeling, we examined the amount of ozone produced in the lower atmosphere for the case of a gamma-ray burst and found that the values are too small to pose a significant additional threat to the biosphere. These results may be extended to other ionizing radiation events, including supernovae and extreme solar proton events.
Alterations of Visual Reaction Time and Short Term Memory in Military Radar Personnel
MORTAZAVI, Seyed Mohammad Javad; TAEB, Shahram; DEHGHAN, Naser
2013-01-01
Background Radar transmitters emit high-power radiofrequency radiation by creation of a high-voltage and high-frequency alternating electrical current. Methods: Health effects of occupational exposure to military radar were investigated. Visual reaction time was recorded with a simple blind computer-assisted-visual reaction time test. To assess the short-term memory, modified Wechsler Memory Scale test was performed. Results: The mean +/- SD reaction time in radar works (N=100) and the control group (N=57) were 238.58 +/− 23.47 milliseconds and 291.86 +/− 28.26 milliseconds (P<0.0001), respectively. The scores of forward digit span in radar works and the control group were 3.56 +/− 0.77 and 4.29 +/− 1.06 (P<0.0001), while the scores of backward digit span in radar works and the control group were 2.70 +/− 0.69 and 3.62 +/− 0.95 (P<0.0001). The scores of word recognition in radar works and the control group were 3.37 +/− 1.13 and 5.86 +/− 1.11 (P<0.0001). Finally, the scores of paired words in radar works and the control group were 13.56 +/− 1.78 and 15.21 +/− 2.20 (P<0.0001). It can be concluded that occupational exposures to radar radiations decreases reaction time, which may lead to a better response to different hazards. Conclusion: To the best of our knowledge, this is the first study to show that occupational exposure to radar microwave radiation leads to decreased reaction time and the lower performance of short-term memory. Altogether, these results indicate that occupational exposure to radar microwave radiations may be linked to some non-detrimental and detrimental health effects. PMID:23785684
Bangotra, Pargin; Mehra, Rohit; Kaur, Kirandeep; Jakhu, Rajan
2016-10-01
The activity concentration of 226 Ra (radium), 232 Th (thorium) and 40 K (potassium) has been measured in the soil samples collected from Mansa and Muktsar districts of Punjab (India) using NaI (Tikl) gamma detector. The concentration of three radionuclides ( 226 Ra, 232 Th and 40 K) in the studied area has been varied from 18±4 to 46±5, 53±7 to 98±8 and 248±54 to 756±110 Bq kg -1 , respectively. Radium equivalent activities (Ra eq ) have been calculated in soil samples for the assessment of the radiation hazards arising due to the use of these soil samples. The absorbed dose rate of 226 Ra, 232 Th and 40 K in studied area has been varied from 8 to 21, 33 to 61 and 9 to 25 nGy h -1 , respectively. The corresponding indoor and outdoor annual effective dose in studied area was 0.38 and 0.09 mSv, respectively. The external and internal hazard has been also calculated for the assessment of radiation hazards in the studied area. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
Radiation -- A Cosmic Hazard to Human Habitation in Space
NASA Technical Reports Server (NTRS)
Lewis, Ruthan; Pellish, Jonathan
2017-01-01
Radiation exposure is one of the greatest environmental threats to the performance and success of human and robotic space missions. Radiation permeates all space and aeronautical systems, challenges optimal and reliable performance, and tests survival and survivability. We will discuss the broad scope of research, technological, and operational considerations to forecast and mitigate the effects of the radiation environment for deep space and planetary exploration.
Nuclear sensor signal processing circuit
Kallenbach, Gene A [Bosque Farms, NM; Noda, Frank T [Albuquerque, NM; Mitchell, Dean J [Tijeras, NM; Etzkin, Joshua L [Albuquerque, NM
2007-02-20
An apparatus and method are disclosed for a compact and temperature-insensitive nuclear sensor that can be calibrated with a non-hazardous radioactive sample. The nuclear sensor includes a gamma ray sensor that generates tail pulses from radioactive samples. An analog conditioning circuit conditions the tail-pulse signals from the gamma ray sensor, and a tail-pulse simulator circuit generates a plurality of simulated tail-pulse signals. A computer system processes the tail pulses from the gamma ray sensor and the simulated tail pulses from the tail-pulse simulator circuit. The nuclear sensor is calibrated under the control of the computer. The offset is adjusted using the simulated tail pulses. Since the offset is set to zero or near zero, the sensor gain can be adjusted with a non-hazardous radioactive source such as, for example, naturally occurring radiation and potassium chloride.
Vasquez, Marcelo
2017-12-22
Vazquez discusses his research projects and how scientists from NASA, national laboratories, and other institutions worldwide have expanded the understanding of the link between ionizing radiation and neurodegeneration.
The Development of Materials for Structures and Radiation Shielding in Aerospace
NASA Technical Reports Server (NTRS)
Kiefer, Richard L.; Orwoll, Robert A.
2001-01-01
Polymeric materials on space vehicles and high-altitude aircraft win be exposed to highly penetrating radiations. These radiations come from solar flares and galactic cosmic rays (GCR). Radiation from solar flares consists primarily of protons with energies less than 1 GeV. On the other hand, GCR consist of nuclei with energies as high as 10(exp 10) GeV. Over 90% of the nuclei in GCR are protons and alpha particles, however there is a small but significant component of particles with atomic numbers greater than ten. Particles with high atomic number (Z) and high energy interact with very high specific ionization and thus represent a serious hazard for humans and electronic equipment on a spacecraft or on high-altitude commercial aircraft (most importantly for crew members who would have long exposures). Neutrons generated by reactions with the high energy particles also represent a hazard both for humans and electronic equipment.
Dust: A major environmental hazard on the earth's moon
DOE Office of Scientific and Technical Information (OSTI.GOV)
Heiken, G.; Vaniman, D.; Lehnert, B.
1990-01-01
On the Earth's Moon, obvious hazards to humans and machines are created by extreme temperature fluctuations, low gravity, and the virtual absence of any atmosphere. The most important other environmental factor is ionizing radiation. Less obvious environmental hazards that must be considered before establishing a manned presence on the lunar surface are the hazards from micrometeoroid bombardment, the nuisance of electro-statically-charged lunar dust, and an alien visual environment without familiar clues. Before man can establish lunar bases and lunar mining operations, and continue the exploration of that planet, we must develop a means of mitigating these hazards. 4 refs.
Cataractogenic potential of ionizing radiations in animal models that simulate man
NASA Astrophysics Data System (ADS)
Lett, J. T.; Cox, A. B.; Lee, A. C.
Aspects of experiments on radiation-induced lenticular opacification during the life spans of two animal models, the New Zealand white rabbit and the rhesus monkey, are compared and contrasted with published results from a life span study of another animal model, the beagle dog, and the most recent data from the ongoing study of the survivors from radiation exposure at Hiroshima and Nagasaki. An important connection among the three animal studies is that all the measurements of cataract indices were made by one of the authors (A.C.L.), so variation from personal subjectivity was reduced to a minimum. The primary objective of the rabbit experiments (radiations involved: 56Fe, 40Ar and 20Ne ions and 60Co γ photons) is an evaluation of hazards to astronauts from galactic particulate radiations. An analogous evaluation of hazards from solar flares during space flight is being made with monkeys exposed to 32, 55, 138 and 400 MeV protons. Conclusions are drawn about the proper use of animal models to simulate radiation responses in man and the levels of radiation-induced lenticular opacification that pose risks to man in space.
NASA Astrophysics Data System (ADS)
Matuo, Youichirou; Miyahara, Shinya; Izumi, Yoshinobu
Radioactive Corrosion Product (CP) is a main cause of personal radiation exposure during maintenance with no breached fuel in fast breeder reactor (FBR) plants. The most important CP is 54Mn and 60Co. In order to establish techniques of radiation dose estimation for radiation workers in radiation-controlled areas of the FBR, the PSYCHE (Program SYstem for Corrosion Hazard Evaluation) code was developed. We add the Particle Model to the conventional PSYCHE analytical model. In this paper, we performed calculation of CP transfer in JOYO using an improved calculation code in which the Particle Model was added to the PSYCHE. The C/E (calculated / experimentally observed) value for CP deposition was improved through use of this improved PSYCHE incorporating the Particle Model. Moreover, among the percentage of total radioactive deposition accounted for by CP in particle form, 54Mn was estimated to constitute approximately 20 % and 60Co approximately 40 % in the cold-leg region. These calculation results are consistent with the measured results for the actual cold-leg piping in the JOYO.
Animal studies of life shortening and cancer risk from space radiation
NASA Astrophysics Data System (ADS)
Wood, D. H.; Yochmowitz, M. G.; Hardy, K. A.; Salmon, Y. L.
The U. S. Air Force study of the delayed effects of single, total body exposures to simulated space radiation in rhesus monkeys is now in its 21st year. Observations on 301 irradiated and 57 age-matched control animals indicate that life expectancy loss from exposure to protons in the energy range encountered in the Van Allen belts and solar proton events can be expressed as a logarithmic function of the dose. The primary causes of life shortening are cancer and endometriosis (an abnormal proliferation of the lining of the uterus in females). Life shortening estimates permit comparison of the risk associated with space radiation exposures to be compared with that of other occupational and environmental hazards, thereby facilitating risk/benefit decisions in the planning and operational phases of manned space missions. Calculations of the relative risk of fatal cancers in the irradiated subjects reveal that the total body surface dose required to double the risk of death from cancer over a 20-year post exposure period varies with the linear energy transfer (LET) of the radiation. The ability to determine the integrated dose and LET spectrum in space radiation exposures of human is, therefore, critical to the assessment of life-time cancer risk.
Investigation of terahertz radiation influence on rat glial cells
Borovkova, Mariia; Serebriakova, Maria; Fedorov, Viacheslav; Sedykh, Egor; Vaks, Vladimir; Lichutin, Alexander; Salnikova, Alina; Khodzitsky, Mikhail
2016-01-01
We studied an influence of continuous terahertz (THz) radiation (0.12 – 0.18 THz, average power density of 3.2 mW/cm2) on a rat glial cell line. A dose-dependent cytotoxic effect of THz radiation is demonstrated. After 1 minute of THz radiation exposure a relative number of apoptotic cells increased in 1.5 times, after 3 minutes it doubled. This result confirms the concept of biological hazard of intense THz radiation. Diagnostic applications of THz radiation can be restricted by the radiation power density and exposure time. PMID:28101417
2007 Annual Health Physics Report for the HEU Transparency Program
DOE Office of Scientific and Technical Information (OSTI.GOV)
Radev, R
2008-04-09
During the 2007 calendar year, Lawrence Livermore National Laboratory (LLNL) provided health physics support for the Highly Enriched Uranium (HEU) Transparency Program for external and internal radiation protection and technical expertise related to BDMS radioactive sources and Russian radiation safety regulatory compliance. For the calendar year 2007, there were 172 person-trips that required dose monitoring of the U.S. monitors. Of the 172 person-trips, 160 person-trips were SMVs and 12 person-trips were Transparency Monitoring Office (TMO) trips. There were 12 monitoring visits by TMO monitors to facilities other than UEIE and 10 to UEIE itself. There were two monitoring visits (sourcemore » changes) that were back to back with 14 monitors. LLNL's Hazard Control Division laboratories provided the dosimetry services for the HEU Transparency monitors.« less
Radiation exposure levels within timber industries in Calabar, Nigeria
Inyang, S. O.; Inyang, I. S.; Egbe, N. O.
2009-01-01
The UNSCEAR (2000) observed that there could be some exposure at work which would require regulatory control but is not really considered. This study was, therefore, set up to evaluate the effective dose in timber industries in Calabar, Nigeria to determine if the evaluated dose levels could lead to any radiological health effect in the workers, and also determine if the industries require regulatory control. The gamma ray exposure at four timber industries measured using an exposure meter were converted to effective dose and compared with the public and occupational values. The evaluated effective dose values in the timber industries were below public and occupational exposure limits and may not necessarily result in any radiological health hazard. Therefore, they may not require regulatory control. PMID:20098544
Effective tree hazard control on forested recreation sites...losses and protection costs evaluated
Lee A. Paine
1967-01-01
Effectiveness of hazard control was evaluated by analyzing data on tree failures, accidents, and control costs on California recreation sites. Results indicate that reduction of limb hazard in oaks and bole hazard in conifers is the most effective form of control. Least effective is limb hazard reduction in conifers. After hazard control goals or control budgets have...
ERIC Educational Resources Information Center
Walsh, Janet
1982-01-01
Discusses issues related to possible health hazards associated with viewing video display terminals. Includes some findings of the 1979 NIOSH report on Potential Hazards of Video Display Terminals indicating level of radiation emitted is low and providing recommendations related to glare and back pain/muscular fatigue problems. (JN)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pollom, Erqi L., E-mail: erqiliu@stanford.edu; Wang, Guanying; Harris, Jeremy P.
Purpose: We examined the impact of intensity modulated radiation therapy (IMRT) on hospitalization rates in the Surveillance, Epidemiology, and End Results (SEER)–Medicare population with anal squamous cell carcinoma (SCC). Methods and Materials: We performed a retrospective cohort study using the SEER-Medicare database. We identified patients with nonmetastatic anal SCC diagnosed between 2001 and 2011 and treated with chemoradiation therapy. We assessed the relation between IMRT and first hospitalization by use of a multivariate competing-risk model, as well as instrumental variable analysis, using provider IMRT affinity as our instrument. Results: Of the 1165 patients included in our study, 458 (39%) receivedmore » IMRT. IMRT use increased over time and was associated more with regional and provider characteristics than with patient characteristics. The 3- and 6-month cumulative incidences of first hospitalization were 41.9% (95% confidence interval [CI], 37.3%-46.4%) and 47.6% (95% CI, 43.0%-52.2%), respectively, for the IMRT cohort and 46.7% (95% CI, 43.0%-50.4%) and 52.1% (95% CI, 48.4%-55.7%), respectively, for the non-IMRT cohort. IMRT was associated with a decreased hazard of first hospitalization compared with 3-dimensional radiation techniques (hazard ratio, 0.70; 95% CI, 0.58-0.84; P=.0002). Instrumental variable analysis suggested an even greater reduction in hospitalizations with IMRT after controlling for unmeasured confounders. There was a trend toward improved overall survival with IMRT, with an adjusted hazard ratio of 0.77 (95% CI, 0.59-1.00; P=.05). Conclusions: The use of IMRT is associated with reduced hospitalizations in elderly patients with anal SCC. Further work is warranted to understand the long-term health and cost impact of IMRT, particularly for patient subgroups most at risk of toxicity and hospitalization.« less
NASA Astrophysics Data System (ADS)
Dorman, L. I.
2005-11-01
We show that an exact forecast of great radiation hazard in space, in the magnetosphere, in the atmosphere and on the ground can be made by using high-energy particles (few GeV/nucleon and higher) whose transportation from the Sun is characterized by a much bigger diffusion coefficient than for small and middle energy particles. Therefore, high energy particles come from the Sun much earlier (8-20 min after acceleration and escaping into solar wind) than the main part of smaller energy particles (more than 30-60 min later), causing radiation hazard for electronics and personal health, as well as spacecraft and aircrafts. We describe here principles of an automatic set of programs that begin with "FEP-Search", used to determine the beginning of a large FEP event. After a positive signal from "FEP-Search", the following programs start working: "FEP-Research/Spectrum", and then "FEP-Research/Time of Ejection", "FEP-Research /Source" and "FEP-Research/Diffusion", which online determine properties of FEP generation and propagation. On the basis of the obtained information, the next set of programs immediately start to work: "FEP-Forecasting/Spacecrafts", "FEP-Forecasting/Aircrafts", "FEP-Forecasting/Ground", which determine the expected differential and integral fluxes and total fluency for spacecraft on different orbits, aircrafts on different airlines, and on the ground, depending on altitude and cutoff rigidity. If the level of radiation hazard is expected to be dangerous for high level technology or/and personal health, the following programs will be used "FEP-Alert/Spacecrafts", "FEP-Alert/ Aircrafts", "FEP-Alert/Ground".
Radiator scald burns: a preventable hazard.
Benmeir, P; Rosenberg, L; Sagi, A; Ben-Yakar, Y
1990-04-01
During the last 13 years 80 patients have been admitted to our department suffering from burns caused by a vehicle's radiator. Ten of them were deeply burned and had to be treated surgically. The preventive aspect of this injury is emphasized.
Solar Energetic Particles -- A Radiation Hazard to Humans and Hardware in Space
NASA Astrophysics Data System (ADS)
Mewaldt, R. A.
2006-10-01
During large solar energetic particle (SEP) events the intensity of >30 MeV protons in nearby interplanetary space can increase by a million times over the steady intensity of galactic cosmic rays, creating a radiation hazard to both humans and hardware in space. With NASA now committed to sending astronauts to the Moon and possibly on to Mars, outside the protective cover of the Earth's magnetosphere, interest in understanding and forecasting large SEP events has taken on a new sense of urgency. The past solar maximum included four of the top ten SEP events of the space era. Fortunately, the array of spacecraft now in interplanetary space has provided greatly improved measurements of the composition and energy spectra of accelerated ions, leading to fresh insights into the nature of these events. The largest SEP events are accelerated by coronal and interplanetary shocks driven by coronal mass ejections (CMEs) traveling at >2000 km/sec. Although shock acceleration is ubiquitous in nature, its efficiency is highly variable, making it difficult to forecast the onset and evolution of large SEP events. This talk will describe the radiation hazards associated with the largest SEP events, discuss their frequency of occurrence, consider a worst-case SEP event, and describe how the radiation risks can be mitigated.
Hazard of ultraviolet radiation emitted in gas metal arc welding of mild steel.
Nakashima, Hitoshi; Utsunomiya, Akihiro; Takahashi, Jyunya; Fujii, Nobuyuki; Okuno, Tsutomu
2016-09-30
Ultraviolet radiation (UVR) emitted during arc welding frequently causes keratoconjunctivitis and erythema in the workplace. The degree of hazard from UVR exposure depends on the welding method and conditions. Therefore, it is important to identify the UVR levels present under various conditions. We experimentally evaluated the UVR levels emitted in gas metal arc welding (GMAW) of mild steel. We used both a pulsed welding current and a non-pulsed welding current. The shielding gases were 80% Ar + 20% CO 2 and 100% CO 2 . The effective irradiance defined in the American Conference of Governmental Industrial Hygienists guidelines was used to quantify the UVR hazard. The effective irradiance measured in this study was in the range of 0.51-12.9 mW/cm 2 at a distance of 500 mm from the arc. The maximum allowable exposure times at these levels are only 0.23-5.9 s/day. The following conclusions were made regarding the degree of hazard from UVR exposure during the GMAW of mild steel: (1) It is more hazardous at higher welding currents than at lower welding currents. (2) At higher welding currents, it is more hazardous when 80% Ar + 20% CO 2 is used as a shielding gas than when 100% CO 2 is used. (3) It is more hazardous for pulsed welding currents than for non-pulsed welding currents. (4) It appears to be very hazardous when metal transfer is the spray type. This study demonstrates that unprotected exposure to UVR emitted by the GMAW of mild steel is quite hazardous.
Hazard of ultraviolet radiation emitted in gas metal arc welding of mild steel
Nakashima, Hitoshi; Utsunomiya, Akihiro; Takahashi, Jyunya; Fujii, Nobuyuki; Okuno, Tsutomu
2016-01-01
Objectives: Ultraviolet radiation (UVR) emitted during arc welding frequently causes keratoconjunctivitis and erythema in the workplace. The degree of hazard from UVR exposure depends on the welding method and conditions. Therefore, it is important to identify the UVR levels present under various conditions. Methods: We experimentally evaluated the UVR levels emitted in gas metal arc welding (GMAW) of mild steel. We used both a pulsed welding current and a non-pulsed welding current. The shielding gases were 80% Ar + 20% CO2 and 100% CO2. The effective irradiance defined in the American Conference of Governmental Industrial Hygienists guidelines was used to quantify the UVR hazard. Results: The effective irradiance measured in this study was in the range of 0.51-12.9 mW/cm2 at a distance of 500 mm from the arc. The maximum allowable exposure times at these levels are only 0.23-5.9 s/day. Conclusions: The following conclusions were made regarding the degree of hazard from UVR exposure during the GMAW of mild steel: (1) It is more hazardous at higher welding currents than at lower welding currents. (2) At higher welding currents, it is more hazardous when 80% Ar + 20% CO2 is used as a shielding gas than when 100% CO2 is used. (3) It is more hazardous for pulsed welding currents than for non-pulsed welding currents. (4) It appears to be very hazardous when metal transfer is the spray type. This study demonstrates that unprotected exposure to UVR emitted by the GMAW of mild steel is quite hazardous. PMID:27488036
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-27
... Awards for Lead-Based Paint Hazard Control, and Lead Hazard Reduction Demonstration Grant Programs for... (OHHLHC) Lead-Based Paint Hazard Control, and Lead Hazard Reduction Demonstration Grant Program Notices of... Grants.gov on December 3, 2012, and amended on January 18, 2013, for the Lead Based Paint Hazard Control...
Elemental analysis and radiation hazards parameters of bauxite located in Saudi Arabia
NASA Astrophysics Data System (ADS)
Alashrah, S.; E Taher, A.
2017-04-01
Since Bauxite has been widely used in industry and in scientific investigations for producing Aluminum, it is important to measure the radionuclides concentrations to determine the health effect. The Bauxite mine is located in Az Zabirah city in Saudi Arabia. The concentrations of the radionuclides in the bauxite samples were measured using γ-ray spectrometer NaI (Tl). The average and range values of the concentrations of 226Ra, 232Th and 40K were 102.2 (141.1-62.7), 156.3 (202.8-102.8) and 116.8 (191.7- 48.9) Bq/kg respectively. These results were compared with the reported ranges in the literature from other locations around the world. The radiation hazard parameters; radium equivalent activity, annual dose, external hazard were also calculated and compared with the recommended levels by International Commission on Radiological Protection (ICRP-60) and united nations scientific committee on the effects of atomic radiation UNSCEAR reports. There are no studies for the natural radioactivity in the bauxite mine in Az Zabirah city, so these results are a start to establishing a database in this location.
Fan, Guoxin; Wang, Yueye; Guo, Changfeng; Lei, Xuefeng; He, Shisheng
2017-05-01
Knowledge and concern degree about work-related radiation hazards remained unknown among orthopedic surgeons. The aim of the cross-sectional study is to investigate whether the knowledge degree of work-related radiation is associated with psychological distress among orthopedic surgeons. This cross-sectional study sent electronic questionnaire via WeChat to orthopedic surgeons nationwide. Concern and knowing degree over radiation exposure was evaluated by a single self-reported question. Professional evaluation of concern degree was reflected by general psychological distress, which was assessed with the Kessler 10 scale (K10) and depressive symptoms with the Center for Epidemiologic Studies Depression Scale (CES-D). Only 43.23% (115/266) respondents knew well about radiation and a total of 78.20% (208/266) respondents considered radiation exposure as a great concern. Among those who reported concerns about radiation exposure, a total of 57.69% (120/208) respondents reported knowing little about radiation. Respondents who reported concerns over radiation exposure were significantly associated with higher scores on CES-D and K10 (P < .05). Among respondents who reported concerns over radiation exposure, those who have fewer knowledge about radiation, had higher CES-D and K10 scores than those who knew well about radiation (P < .05). Among respondents who reported no concerns over radiation exposure, those who knew little about radiation still had higher CES-D and K10 scores (P < .05). Fewer radiation knowledge tends to induce more radiation concerns associated with higher psychological distress in orthopedic surgeons. Radiation knowledge should be enhanced for surgeons who daily work with radiation-related fluoroscopy.
Fan, Guoxin; Wang, Yueye; Guo, Changfeng; Lei, Xuefeng; He, Shisheng
2017-01-01
Abstract Knowledge and concern degree about work-related radiation hazards remained unknown among orthopedic surgeons. The aim of the cross-sectional study is to investigate whether the knowledge degree of work-related radiation is associated with psychological distress among orthopedic surgeons. This cross-sectional study sent electronic questionnaire via WeChat to orthopedic surgeons nationwide. Concern and knowing degree over radiation exposure was evaluated by a single self-reported question. Professional evaluation of concern degree was reflected by general psychological distress, which was assessed with the Kessler 10 scale (K10) and depressive symptoms with the Center for Epidemiologic Studies Depression Scale (CES-D). Only 43.23% (115/266) respondents knew well about radiation and a total of 78.20% (208/266) respondents considered radiation exposure as a great concern. Among those who reported concerns about radiation exposure, a total of 57.69% (120/208) respondents reported knowing little about radiation. Respondents who reported concerns over radiation exposure were significantly associated with higher scores on CES-D and K10 (P < .05). Among respondents who reported concerns over radiation exposure, those who have fewer knowledge about radiation, had higher CES-D and K10 scores than those who knew well about radiation (P < .05). Among respondents who reported no concerns over radiation exposure, those who knew little about radiation still had higher CES-D and K10 scores (P < .05). Fewer radiation knowledge tends to induce more radiation concerns associated with higher psychological distress in orthopedic surgeons. Radiation knowledge should be enhanced for surgeons who daily work with radiation-related fluoroscopy. PMID:28538368
Code of Practice for the Use of Ionizing Radiations in Secondary Schools.
ERIC Educational Resources Information Center
National Health and Medical Research Council, Canberra (Australia).
The appreciation of the potential hazard of ionizing radiation led to the setting up of national, and later, international commissions for the defining of standards of protection for the occupationally exposed worker in the use of ionizing radiation. However, in the last twenty years, with the large scale development of nuclear energy, the need…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bishop, Andrew J.; Tao, Randa; Rebueno, Neal C.
Purpose: To investigate local control, survival outcomes, and predictors of local relapse for patients treated with spine stereotactic body radiation therapy. Methods and Materials: We reviewed the records of 332 spinal metastases consecutively treated with stereotactic body radiation therapy between 2002 and 2012. The median follow-up for all living patients was 33 months (range, 0-111 months). Endpoints were overall survival and local control (LC); recurrences were classified as either in-field or marginal. Results: The 1-year actuarial LC and overall survival rates were 88% and 64%, respectively. Patients with local relapses had poorer dosimetric coverage of the gross tumor volume (GTV) compared withmore » patients without recurrence (minimum dose [Dmin] biologically equivalent dose [BED] 23.9 vs 35.1 Gy, P<.001; D98 BED 41.8 vs 48.1 Gy, P=.001; D95 BED 47.2 vs 50.5 Gy, P=.004). Furthermore, patients with marginal recurrences had poorer prescription coverage of the GTV (86% vs 93%, P=.01) compared with those with in-field recurrences, potentially because of more upfront spinal canal disease (78% vs 24%, P=.001). Using a Cox regression univariate analysis, patients with a GTV BED Dmin ≥33.4 Gy (median dose) (equivalent to 14 Gy in 1 fraction) had a significantly higher 1-year LC rate (94% vs 80%, P=.001) compared with patients with a lower GTV BED Dmin; this factor was the only significant variable on multivariate Cox analysis associated with LC (P=.001, hazard ratio 0.29, 95% confidence interval 0.14-0.60) and also was the only variable significant in a separate competing risk multivariate model (P=.001, hazard ratio 0.30, 95% confidence interval 0.15-0.62). Conclusions: Stereotactic body radiation therapy offers durable control for spinal metastases, but there is a subset of patients that recur locally. Patients with local relapse had significantly poorer tumor coverage, which was likely attributable to treatment planning directives that prioritized the spinal cord constraints over tumor coverage. When possible, we recommend maintaining a GTV Dmin above 14 Gy in 1 fraction and 21 Gy in 3 fractions.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Orman, Amber; Koru-Sengul, Tulay; Miao, Feng
2014-12-01
Purpose/Objective(s): To evaluate the effects of various patient characteristics and radiation therapy treatment variables on outcomes in advanced-stage retinoblastoma. Methods and Materials: This was a retrospective review of 41 eyes of 30 patients treated with external beam radiation therapy between June 1, 1992, and March 31, 2012, with a median follow-up time of 133 months (11 years). Outcome measures included overall survival, progression-free survival, local control, eye preservation rate, and toxicity. Results: Over 90% of the eyes were stage V. Definitive external beam radiation therapy (EBRT) was delivered in 43.9% of eyes, adjuvant EBRT in 22% of eyes, and second-line/salvage EBRT inmore » 34.1% of eyes. A relative lens sparing (RLS) technique was used in 68.3% of eyes and modified lens sparing (MLS) in 24.4% of eyes. Three eyes were treated with other techniques. Doses ≥45 Gy were used in 68.3% of eyes. Chemotherapy was a component of treatment in 53.7% of eyes. The 10-year overall survival was 87.7%, progression-free survival was 80.5%, and local control was 87.8%. White patients had significantly better overall survival than did African-American patients in univariate analysis (hazard ratio 0.09; 95% confidence interval 0.01-0.84; P=.035). Toxicity was seen in 68.3% of eyes, including 24.3% with isolated acute dermatitis. Conclusions: External beam radiation therapy continues to be an effective treatment modality for advanced retinoblastoma, achieving excellent long-term local control and survival with low rates of treatment-related toxicity and secondary malignancy.« less
Are Computers Hazardous to Your Child's Health?
ERIC Educational Resources Information Center
Personal Computing, 1981
1981-01-01
Two potential health hazards have been suggested in relation to long-term use of computer video monitors: radiation and vision problems (fatigue, eyestrain, eye damage). This article examines some available evidence on these issues. Journal availability: Hayden Publishing Company, 50 Essex Street, Rochelle Park, NJ 07662. (SJL)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gill, Beant S.; Lin, Jeff F.; Krivak, Thomas C.
Purpose: To utilize the National Cancer Data Base to evaluate trends in brachytherapy and alternative radiation therapy utilization in the treatment of cervical cancer, to identify associations with outcomes between the various radiation therapy modalities. Methods and Materials: Patients with International Federation of Gynecology and Obstetrics stage IIB-IVA cervical cancer in the National Cancer Data Base who received treatment from January 2004 to December 2011 were analyzed. Overall survival was estimated by the Kaplan-Meier method. Univariate and multivariable analyses were performed to identify factors associated with type of boost radiation modality used and its impact on survival. Results: A totalmore » of 7654 patients had information regarding boost modality. A predominant proportion of patients were Caucasian (76.2%), had stage IIIB (48.9%) disease with squamous (82.0%) histology, were treated at academic/research centers (47.7%) in the South (34.8%), and lived 0 to 5 miles (27.9%) from the treating facility. A majority received brachytherapy (90.3%). From 2004 to 2011, brachytherapy use decreased from 96.7% to 86.1%, whereas intensity modulated radiation therapy (IMRT) and stereotactic body radiation therapy (SBRT) use increased from 3.3% to 13.9% in the same period (P<.01). Factors associated with decreased brachytherapy utilization included older age, stage IVA disease, smaller tumor size, later year of diagnosis, lower-volume treatment centers, and facility type. After controlling for significant factors from survival analyses, IMRT or SBRT boost resulted in inferior overall survival (hazard ratio, 1.86; 95% confidence interval, 1.35-2.55; P<.01) as compared with brachytherapy. In fact, the survival detriment associated with IMRT or SBRT boost was stronger than that associated with excluding chemotherapy (hazard ratio, 1.61′ 95% confidence interval, 1.27-2.04′ P<.01). Conclusions: Consolidation brachytherapy is a critical treatment component for locally advanced cervical cancer; however, there has been declining utilization of brachytherapy. Increased use of IMRT and SBRT boost coupled with increased mortality risk should raise concerns about utilizing these approaches over brachytherapy.« less
14 CFR 417.413 - Hazard areas.
Code of Federal Regulations, 2014 CFR
2014-01-01
... controls during public access. A launch operator must establish procedural controls that prevent hazardous... that system hazard controls are in place that prevent initiation of a hazardous event. Hazard controls... devices or other restraints on system actuation switches or other controls to eliminate the possibility of...
14 CFR 417.413 - Hazard areas.
Code of Federal Regulations, 2010 CFR
2010-01-01
... controls during public access. A launch operator must establish procedural controls that prevent hazardous... that system hazard controls are in place that prevent initiation of a hazardous event. Hazard controls... devices or other restraints on system actuation switches or other controls to eliminate the possibility of...
14 CFR 417.413 - Hazard areas.
Code of Federal Regulations, 2011 CFR
2011-01-01
... controls during public access. A launch operator must establish procedural controls that prevent hazardous... that system hazard controls are in place that prevent initiation of a hazardous event. Hazard controls... devices or other restraints on system actuation switches or other controls to eliminate the possibility of...
Attitude and awareness of general dental practitioners toward radiation hazards and safety.
Aravind, B S; Joy, E Tatu; Kiran, M Shashi; Sherubin, J Eugenia; Sajesh, S; Manchil, P Redwin Dhas
2016-10-01
The aim and objective is to evaluate the level of awareness and attitude about radiation hazards and safety practices among general dental practitioners in Trivandrum District, Kerala, India. A questionnaire-based cross-sectional study was conducted among 300 general dental practitioners in Trivandrum District, Kerala, India. Postanswering the questions, a handout regarding radiation safety and related preventive measures was distributed to encourage radiation understanding and protection. Statistical analysis were done by assessing the results using Chi-square statistical test, t -test, and other software (Microsoft excel + SPSS 20.0 trail version). Among 300 general practitioners (247 females and 53 males), 80.3% of the practitioners were found to have a separate section for radiographic examination in their clinics. Intraoral radiographic machines were found to be the most commonly (63.3%) used radiographic equipment while osteoprotegerin was the least (2%). Regarding the practitioner's safety measures, only 11.7% of them were following all the necessary steps while 6.7% clinicians were not using any safety measure in their clinic, and with respect to patient safety, only 9.7% of practitioners were following the protocol. The level of awareness of practitioners regarding radiation hazards and safety was found to be acceptable. However, implementation of their knowledge with respect to patient and personnel safety was found wanting. Insisting that they follow the protocols and take necessary safety measures by means of continuing medical education programs, pamphlets, articles, and workshops is strongly recommended.
Health Issues: Do Cell Phones Pose a Health Hazard?
... confused with the effects from other types of electromagnetic energy. Very high levels of electromagnetic energy, such as is found in X-rays ... light, infrared radiation (heat) and other forms of electromagnetic radiation with relatively low frequencies. While RF energy ...
Field strength measurements of speed measuring radar units
DOT National Transportation Integrated Search
1981-06-01
The objective of this project was to measure the microwave radiation emitted by speed measuring radar units to obtain a data base for evaluating the potential radiation hazards of these devices. Measurements were taken both in free-space and with the...
Manned Mars mission radiation environment and radiobiology
NASA Technical Reports Server (NTRS)
Nachtwey, D. S.
1986-01-01
Potential radiation hazards to crew members on manned Mars missions are discussed. It deals briefly with radiation sources and environments likely to be encountered during various phases of such missions, providing quantitative estimates of these environments. Also provided are quantitative data and discussions on the implications of such radiation on the human body. Various sorts of protective measures are suggested. Recent re-evaluation of allowable dose limits by the National Council of Radiation Protection is discussed, and potential implications from such activity are assessed.
Determination of naturally occurring radionuclides in soil samples of Ayranci, Turkey
NASA Astrophysics Data System (ADS)
Agar, Osman; Eke, Canel; Boztosun, Ismail; Emin Korkmaz, M.
2015-04-01
The specific activity, radiation hazard index and the annual effective dose of the naturally occurring radioactive elements (238U, 232Th and 40K) were determined in soil samples collected from 12 different locations in Ayranci region by using a NaI(Tl) gamma-ray spectrometer. The measured activity concentrations of the natural radionuclides in studied soil samples were compared with the corresponding results of different countries and the internationally reported values. From the analysis, it is found that these materials may be safely used as construction materials and do not pose significant radiation hazards.
Radiation Hazards and Countermeasures for Human Space Flight
NASA Technical Reports Server (NTRS)
Adams, James H., Jr.
2004-01-01
Protection of the astronauts from space radiation is NASA's moral and legal responsibility. There can be no manned deep space missions without adequate protection from the ionizing radiation in space. There are tow parts to radiation protection, determining the effects of space radiation on humans so that adequate exposure limits can be set and providing radiation protection that insures those limits will not be exceeded. This talk will review the status of work on these two parts and identify areas that are currently being investigated and gaps in the research that have been identified.
NASA Technical Reports Server (NTRS)
Lushbaugh, C. C.
1972-01-01
Results of clinical studies of radiation effects on man are used to evaluate space radiation hazards encountered during manned space travel. Considered are effects of photons as well as of mixed fission neutrons and gamma irradiations in establishing body radiosensitivity and tolerance levels. Upper and lower dose-response-time relations for acute radiation syndromes in patients indicate that man is more than sufficiently radioresistant to make the risks of an early radiation effect during one short space mission intangibly small in relation to the other nonradiation risks involved.
Accumulated Delivered Dose Response of Stereotactic Body Radiation Therapy for Liver Metastases
DOE Office of Scientific and Technical Information (OSTI.GOV)
Swaminath, Anand; Massey, Christine; Brierley, James D.
2015-11-01
Purpose: To determine whether the accumulated dose using image guided radiation therapy is a stronger predictor of clinical outcomes than the planned dose in stereotactic body radiation therapy (SBRT) for liver metastases. Methods and Materials: From 2003 to 2009, 81 patients with 142 metastases were treated in institutional review board–approved SBRT studies (5-10 fractions). Patients were treated during free breathing (with or without abdominal compression) or with controlled exhale breath-holding. SBRT was planned on a static exhale computed tomography (CT) scan, and the minimum planning target volume dose to 0.5 cm{sup 3} (minPTV) was recorded. The accumulated minimum dose to themore » 0.5 cm{sup 3} gross tumor volume (accGTV) was calculated after performing dose accumulation from exported image guided radiation therapy data sets registered to the planning CT using rigid (2-dimensional MV/kV orthogonal) or deformable (3-dimensional/4-dimensional cone beam CT) image registration. Univariate and multivariate Cox regression models assessed the factors influencing the time to local progression (TTLP). Hazard ratios for accGTV and minPTV were compared using model goodness-of-fit and bootstrapping. Results: Overall, the accGTV dose exceeded the minPTV dose in 98% of the lesions. For 5 to 6 fractions, accGTV doses of >45 Gy were associated with 1-year local control of 86%. On univariate analysis, the cancer subtype (breast), smaller tumor volume, and increased dose were significant predictors for improved TTLP. The dose and volume were uncorrelated; the accGTV dose and minPTV dose were correlated and were tested separately on multivariate models. Breast cancer subtype, accGTV dose (P<.001), and minPTV dose (P=.02) retained significance in the multivariate models. The univariate hazard ratio for TTLP for 5-Gy increases in accGTV versus minPTV was 0.67 versus 0.74 (all patients; 95% confidence interval of difference 0.03-0.14). Goodness-of-fit testing confirmed the accGTV dose as a stronger dose–response predictor than the minPTV dose. Conclusions: The accGTV dose is a better predictor of TTLP than the minPTV dose for liver metastasis SBRT. The use of modern image guided radiation therapy in future analyses of dose–response outcomes should increase the concordance between the planned and delivered doses.« less
Test Operations Procedure (TOP) 03-2-504A Safety Evaluation of Small Arms and Medium Caliber Weapons
2013-05-29
Assessment HHAR Health Hazard Assessment Report HERO Hazards of Electromagnetic Radiation to Ordnance in. inch J Joule km/hr kilometers per hour...help standardize testing and to specify tests commonly used to identify and assess safety hazards associated with the use of small arms. The...19b. TELEPHONE NUMBER (include area code) Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std. Z39-18
NASA Astrophysics Data System (ADS)
Michael, Ralph; Wegener, Alfred
2004-08-01
Hazards from the optical radiation of an operating microscope that cause damage at the corneal, lenticular, and retinal levels were investigated; we considered, in particular, ultraviolet radiation (UVR) and blue light. The spectral irradiance from a Zeiss operation microscope OPMI VISU 200 was measured in the corneal plane between 300 and 1100 nm. Effective irradiance and radiance were calculated with relative spectral effectiveness data from the American Conference for Governmental and Industrial Hygienists. Safe exposure time to avoid UVR injury to the lens and cornea was found to be 2 h without a filter, 4 h with a UVR filter, 200 h with a yellow filter, and 400 h with a filter combination. Safe exposure time to avoid retinal photochemical injury was found to be 3 min without a filter and with a UVR filter, 10 min with a yellow filter, and 49 min with a filter combination. The effective radiance limit for retinal thermal injury was not exceeded. The hazard due to the UVR component from the operating microscope is not critical, and operation time can be safely prolonged with the use of appropriate filters. The retinal photochemical hazard appears critical without appropriate filters, permitting only some minutes of safe exposure time. The calculated safe exposure times are for worst-case conditions and maximal light output and include a safety factor.
Michael, Ralph; Wegener, Alfred
2004-08-01
Hazards from the optical radiation of an operating microscope that cause damage at the corneal, lenticular, and retinal levels were investigated; we considered, in particular, ultraviolet radiation (UVR) and blue light. The spectral irradiance from a Zeiss operation microscope OPMI VISU 200 was measured in the corneal plane between 300 and 1100 nm. Effective irradiance and radiance were calculated with relative spectral effectiveness data from the American Conference for Governmental and Industrial Hygienists. Safe exposure time to avoid UVR injury to the lens and cornea was found to be 2 h without a filter, 4 h with a UVR filter, 200 a yellow filter, and 400 h with a filter combination. Safe exposure time to avoid retinal photochemical injury was found to be 3 min without a filter and with a UVR filter, 10 min with a yellow filter, and 49 min with a filter combination. The effective radiance limit for retinal thermal injury was not exceeded. The hazard due to the UVR component from the operating microscope is not critical, and operation time can be safely prolonged with the use of appropriate filters. The retinal photochemical hazard appears critical without appropriate filters, permitting only some minutes of safe exposure time. The calculated safe exposure times are for worst-case conditions and maximal light output and include a safety factor.
THE QUESTIONS OF HEALTH HAZARDS FROM THE INHALATION OF INSOLUBLE URANIUM AND THORIUM OXIDES
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hodge, H.C.; Thomas, R.G.
1958-10-31
The insoluble compounds of uranium and thorium, particularly the oxides, are important in the development of atomic energy. Thc questions of health hazards from exposures to dusts of these insoluble compounds are strikily simlar in many but not all respects, Among the similarities may be listed the following facts: The insoluble compounds present no chemical hazard. Both uranium and thorium dioxides, for example, are remarkably inert physiologically. No radiation injuries have so far been described in the lungs of experimental animals inhaling dust concentrations many times the recommended MAC. The lungs of a few dogs studied seven years after excessivemore » inhalation exposures to ThO/sub 2/ gave negative histological findings although high concentrations of thorium were present. The MACs for insoluble uranium and for inxoluble thorium dusts are identical, specifically 3 x 10/sup -11/ c/1. Calculated on a radiation basis, a lower MAC is appropriate for thorium. Based on a considerable body of information from cted. For both uranium and thorium dioxides fecal excretion reflects the immediate exposure to dusty atmospheres. Urine analyses are a prime index of uranium exposure whereas the presence of the much less soluble thorium dioxide in the lung cannot be thus assessed. Breath thoron extimnations or possibly measurements using a whole body counter have been recommended as indices of thorium exposure. The fundamental question depends on the radiosensitivity of the lung and of the pulmonary lymph nodes; neither the production of radiation injury nor the production of cancer are evaluated at present with respect to dosage of radiation. The lung tissues of the dogs described above must have received several thousand rem during the 7 year period. The pulmonary lymph modes must have received considerably more radiation because the concentrations in these nodes e use of the insoluble oxides and the low MACs combine to raise recurring questions of health hazards. (auth)« less
The Underwater Radiation Spectral Identification System (URSIS) is a portable spectrometer used for the in situ detection of radioactivity in the marine environment. This paper reports on the first time application of this technology to assess, in a preliminary manner, the potent...
Radiation Issues Surrounding Very High Energy Ion Implantation
NASA Astrophysics Data System (ADS)
White, Nicholas R.; Tokoro, Nobuhiro; Bell, Edward
2008-11-01
The requirements for doping of semiconductor device layers have pushed the boundaries of implanter energy, for example, with the use of >5 MeV energies for fabrication of optical sensory arrays. With the higher energy comes the need to understand associated radiation risks. This paper presents original measured data quantifying the range in which safe commercial implantation can be accomplished without radiation hazards.
Space Exploration: Where We Have Been, Where We Are and Where We Are Going: A Human Perspective
NASA Technical Reports Server (NTRS)
Tripathi, R. K.
2005-01-01
NASA is moving forward towards the agency's new vision for space exploration in the 21st Century encompassing a broad range of human and robotic missions including missions to Moon, Mars and beyond. Exposure from the hazards of severe space radiation in deep space long duration missions is the show stopper. Langley has developed state-of-the-art radiation protection and shielding technology for space missions. The payload penalty demands a very stringent requirement on the design of the spacecrafts for human deep space missions. The exploration beyond low Earth orbit (LEO) to enable routine access to more interesting regions of space will require protection from the hazards of the accumulated exposures of space radiation, Galactic Cosmic Rays (GCR) and Solar Particle Events (SPE), and minimizing the production of secondary radiation is a great advantage. The better understanding of radiation environment (GCR & SPE) and their interaction is a key to the success of the program due to the vital role and importance of cosmic rays for space missions.
Kim, Jong Bin; Lee, Jaehoon
2017-01-01
Purpose The aim of the present study was to identify the radiation hazards to vascular surgeons and scrub nurses working in mobile fluoroscopy equipped hybrid vascular operation rooms; additionally, to estimate cumulative cancer risk due to certain exposure dosages. Methods The study was conducted prospectively in 71 patients (53 men and 18 women) who had undergone vascular intervention at our hybrid vascular theater for 6 months. OEC 9900 fluoroscopy was used as mobile C-arm. Exposure dose (ED) was measured by attaching optically stimulated luminescence at in and outside of the radiation protectors. To measure X-ray scatter with the anthropomorphic phantom model, the dose was measured at 3 distances (20, 50, 100 cm) and 3 angles (horizontal, upward 45°, downward 45°) using a personal gamma radiation dosimeter, Ecotest CARD DKG-21, for 1, 3, 5, 10 minutes. Results Lifetime attributable risk of cancer was estimated using the approach of the Biological Effects of Ionizing Radiation report VII. The 6-month ED of vascular surgeons and scrub nurses were 3.85, 1.31 mSv, respectively. The attenuation rate of lead apron, neck protector and goggle were 74.6%, 60.6%, and 70.1%, respectively. All cancer incidences among surgeons and scrub nurses correspond to 2,355 and 795 per 100,000 persons. The 10-minute dose at 100-cm distance was 0.004 mSv at horizontal, 0.009 mSv at downward 45°, 0.003 mSv at upward 45°. Conclusion Although yearly radiation hazards for vascular surgeons and scrub nurses are still within safety guidelines, protection principles can never be too stringent when aiming to minimize the cumulative harmful effects. PMID:28289670
Some current advances in biophysical applications of ionizing radiation for health preservation
NASA Astrophysics Data System (ADS)
Watt, D. E.
1987-03-01
Radiation Physics is a subject of major importance in application to health preservation through investigative, diagnostic, analytical and therapeutic procedures for clinical purposes. Its benefits are enormous and well-established. However there are also hazards and so it is important for health preservation purposes to establish quantitatively the degree of risk undergone by persons exposed to radiation in the natural environment, in their occupations and in medical treatment. In this paper a brief indication is given of the extensive utilisation of the unique properties of radiation in biomedical application. This is followed by fuller discussion on new developments in our understanding of radiation damage mechanisms in radiotherapy and radiological protection. An example is given in biomedical research into the role of trace elements in gallstone formation using neutron activation anaysis, proton induced X-ray emission and X-ray fluorescence analysis as complementary techniques for maximising sensitivity in multielemental analysis by induced radiation. Procedures are described for measuring radiation effect, at bone/ tissue and lung/air interfaces, due to the uptake of radioactive material from the natural environment. Finally a topical subject in nuclear medicine viz. the possible advantages and hazards of Auger electron cascades resulting from inner shell vacancies in electron capture nuclides, is examined in the light of new evidence.
Tandberg, Daniel J; Oyekunle, Taofik; Lee, W Robert; Wu, Yuan; Salama, Joseph K; Koontz, Bridget F
2018-06-01
To compare acute/late toxicity and biochemical control in contemporaneous prostate cancer patient cohorts treated with hypofractionated postprostatectomy radiation therapy (hypoPORT) or conventional PORT (coPORT). Consecutive patients treated with intensity modulated hypoPORT (2.5 Gy per fraction, median cumulative dose 65 Gy [range, 57.5-70 Gy]) or coPORT (1.8-2.0 Gy per fraction, median cumulative dose 66 Gy [range, 60-74 Gy]) between 2005 and 2016 at 2 institutions constituted the study cohort. Acute toxicity and cumulative late grade 2 and ≥3 genitourinary (GU) and gastrointestinal (GI) toxicity incidences were calculated for all patients using the Kaplan-Meier method and compared between cohorts. Biochemical progression-free survival (bPFS) was calculated in patients with ≥12 months' follow-up. Median follow-up for all 461 patients was 38.6 months. Of the 461 patients, 167 (36%) received hypoPORT, and 294 (64%) patients received coPORT. The hypoPORT cohort had significantly worse baseline urinary incontinence. Acute grade ≥2 GU toxicity was more common after hypoPORT (22% vs 8%) (P = .0001). Late grade ≥3 GU toxicity cumulative incidence at 6 years was 11% (hypoPORT) and 4% (coPORT) (P = .0081). However, hypoPORT was not associated with late grade ≥2 GU toxicity on multivariate analysis (hazard ratio 1.39, 95% confidence interval 0.86-2.34) (P = .18). There was no difference in acute or late GI toxicity. In the subset of patients with ≥12 month's follow-up (n = 364, median follow-up 52 months), 4-year bPFS was 78% (95% CI 69.4-85.0) after hypoPORT (P = .0038) and 65% (95% CI 57.6-71.1) after coPORT. HypoPORT was not significant for bPFS on multivariate analysis (hazard ratio 0.64, 95% CI 0.41-1.02, P = .059). HypoPORT shows promising early biochemical control. After controlling for baseline urinary function, hypoPORT was not associated with greater GU toxicity than coPORT. © 2018 Elsevier Inc. Copyright © 2018 Elsevier Inc. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
McDonald, Mark W., E-mail: mark.mcdonald@emory.edu; Zolali-Meybodi, Omid; Lehnert, Stephen J.
Purpose: To report the clinical outcomes of head and neck reirradiation with proton therapy. Methods and Materials: From 2004 to 2014, 61 patients received curative-intent proton reirradiation, primarily for disease involving skull base structures, at a median of 23 months from the most recent previous course of radiation. Most had squamous cell (52.5%) or adenoid cystic (16.4%) carcinoma. Salvage surgery before reirradiation was undertaken in 47.5%. Gross residual disease was present in 70.5%. For patients with microscopic residual disease, the median dose of reirradiation was 66 Gy (relative biological effectiveness), and for gross disease was 70.2 Gy (relative biological effectiveness). Concurrent chemotherapy was givenmore » in 27.9%. Results: The median follow-up time was 15.2 months and was 28.7 months for patients remaining alive. The 2-year overall survival estimate was 32.7%, and the median overall survival was 16.5 months. The 2-year cumulative incidence of local failure with death as a competing risk was 19.7%; regional nodal failure, 3.3%; and distant metastases, 38.3%. On multivariable analysis, Karnofsky performance status ≤70%, the presence of a gastrostomy tube before reirradiation, and an increasing number of previous courses of radiation therapy were associated with a greater hazard ratio for death. A cutaneous primary tumor, gross residual disease, increasing gross tumor volume, and a lower radiation dose were associated with a greater hazard ratio for local failure. Grade ≥3 toxicities were seen in 14.7% acutely and 24.6% in the late setting, including 3 treatment-related deaths. Conclusions: Reirradiation with proton therapy, with or without chemotherapy, provided reasonable locoregional disease control, toxicity profiles, and survival outcomes for an advanced-stage and heavily pretreated population. Additional data are needed to identify which patients are most likely to benefit from aggressive efforts to achieve local disease control and to evaluate the potential benefit of proton therapy relative to other modalities of reirradiation.« less
Radiation predictions and shielding calculations for RITS-6
DOE Office of Scientific and Technical Information (OSTI.GOV)
Maenchen, John Eric; O'Malley, John; Kensek, Ronald Patrick
2005-06-01
The mission of Radiographic Integrated Test Stand-6 (RITS-6) facility is to provide the underlying science and technology for pulsed-power-driven flash radiographic X-ray sources for the National Nuclear Security Administration (NNSA). Flash X-ray radiography is a penetrating diagnostic to discern the internal structure in dynamic experiments. Short (~50 nanosecond (ns) duration) bursts of very high intensity Xrays from mm-scale source sizes are required at a variety of voltages to address this mission. RITS-6 was designed and is used to both develop the accelerator technology needed for these experiments and serves as the principal test stand to develop the high intensity electronmore » beam diodes that generate the required X-ray sources. RITS is currently in operation with three induction cavities (RITS-3) with a maximum voltage output of 5.5 MV and is classified as a low hazard non-nuclear facility in accordance with CPR 400.1.1, Chapter 13, Hazards Identification/Analysis and Risk Management. The facility will be expanded from three to six cavities (RITS-6) effectively doubling the operating voltage. The increase in the operating voltage to above 10 MV has resulted in RITS-6 being classified as an accelerator facility. RITS-6 will come under DOE Order 420.2B, Safety of Accelerator Facilities. The hazards of RITS are detailed in the "Safety Assessment Document for the Radiographic Integrated Test Stand Facility." The principal non-industrial hazard is prompt x-ray radiation. As the operating voltage is increased, both the penetration power and the total amount (dose) of x-rays are increased, thereby increasing the risk to local personnel. Fixed site shielding (predominantly concrete walls and a steel/lead skyshine shield) is used to attenuate these x-rays and mitigate this risk. This SAND Report details the anticipated x-ray doses, the shielding design, and the anticipated x-ray doses external to this shielding structure both in areas where administrative access control restricts occupation and in adjacent uncontrolled areas.« less
76 FR 45600 - Order of Succession for the Office of Healthy Homes and Lead Hazard Control
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-29
... Office of Healthy Homes and Lead Hazard Control AGENCY: Office of Healthy Homes and Lead Hazard Control... Healthy Homes and Lead Hazard Control for the Department of Housing and Urban Development designates the Order of Succession for the Office of Healthy Homes and Lead Hazard Control. This Order of Succession...
Ionizing radiations, underground world and nuclear tests in Algeria
NASA Astrophysics Data System (ADS)
Chama, Allel
2010-05-01
Today, the exposure to ionizing radiations, is still a real great physical hazard in the world at various levels until the nuclear tests which led to a rich and lawful debate, and needs the installation of preventive rules through technical and medical aspects during the use of the radioactive sources, (theradioprotection). Concerning the occupational health, the pathology of the ionizing radiations is repaired under occupational disease. Our interest is to highlight this physical hazard, which represents an important chapter of the occupational pathology in its effects and prevention of the workers exposed in Algeria. The second aim of the paper is to highlight the historical aspect of the risk of ionizing radiations and consequences causes by the French nuclear tests in In Eker (underground galleries of the mountain of Hoggar in the south of Algeria in 1961), whose effects present a great damage on the health of the Algerian captive, and "workers", indigenous population and environment until now. This event deserves its place as much as that of Hiroshima and Nagasaki (1945).
Passive radiation shielding considerations for the proposed space elevator
NASA Astrophysics Data System (ADS)
Jorgensen, A. M.; Patamia, S. E.; Gassend, B.
2007-02-01
The Earth's natural van Allen radiation belts present a serious hazard to space travel in general, and to travel on the space elevator in particular. The average radiation level is sufficiently high that it can cause radiation sickness, and perhaps death, for humans spending more than a brief period of time in the belts without shielding. The exact dose and the level of the related hazard depends on the type or radiation, the intensity of the radiation, the length of exposure, and on any shielding introduced. For the space elevator the radiation concern is particularly critical since it passes through the most intense regions of the radiation belts. The only humans who have ever traveled through the radiation belts have been the Apollo astronauts. They received radiation doses up to approximately 1 rem over a time interval less than an hour. A vehicle climbing the space elevator travels approximately 200 times slower than the moon rockets did, which would result in an extremely high dose up to approximately 200 rem under similar conditions, in a timespan of a few days. Technological systems on the space elevator, which spend prolonged periods of time in the radiation belts, may also be affected by the high radiation levels. In this paper we will give an overview of the radiation belts in terms relevant to space elevator studies. We will then compute the expected radiation doses, and evaluate the required level of shielding. We concentrate on passive shielding using aluminum, but also look briefly at active shielding using magnetic fields. We also look at the effect of moving the space elevator anchor point and increasing the speed of the climber. Each of these mitigation mechanisms will result in a performance decrease, cost increase, and technical complications for the space elevator.
Absar, Nurul; Rahman, M Mashiur; Kamal, Masud; Siddique, Naziba; Chowdhury, Mantazul Islam
2014-11-01
Radioactivity in the soil of a tea garden in the Fatickchari area in Chittagong, Bangladesh, was measured using a high-resolution HPGe detector. The soil samples were collected from depths of up to 20 cm beneath the soil surface. The activity concentrations of naturally occurring (238)U and (232)Th were observed to be in the range of 27 ± 7 to 53 ± 8 Bq kg(-1) and 36 ± 11 to 72 ± 11 Bq kg(-1), respectively. The activity concentration of (40)K ranged from 201 ± 78 to 672 ± 81 Bq kg(-1), and the highest activity of fallout (137)Cs observed was 10 ± 1 Bq kg(-1). The average activity concentration observed for (238)U was 39 ± 8 Bq kg(-1), for (232)Th was 57 ± 11 Bq kg(-1), for (40)K was 384 ± 79 Bq kg(-1) and for (137)Cs was 5 ± 0.5 Bq kg(-1). The radiological hazard parameters (representative level index, radium equivalent activity, outdoor and indoor dose rates, outdoor and indoor annual effective dose equivalents, and radiation hazard index) were calculated from the radioactivity in the soil. © The Author 2014. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Radiation Oncology.
1993-04-01
34 in the remainder of this "• IPS. Ensure that system safety, Section refer to the DoD format paragraph health hazards, and environmental for the...hazardous materials is controlled in the manner which protects human health and the environment at the least cost. Hazardous Material Control and Management...of hazardous materials is controlled in a manner which protects human health and the environment at the least cost. Hazardous Material Control and
BLAST LOADING AND RESPONSE OF UNDERGROUND CONCRETE-ARCH PROTECTIVE STRUCTURES
DOE Office of Scientific and Technical Information (OSTI.GOV)
Flathau, W.J.; Breckenridge, R.A.; Wiehle, C.K.
1959-06-01
Four reinforced-concrete arch structures, with the top of arch crown 4 ft below ground surface, were exposed at high overpressure ranges from Priscilla Burst in order to obtain data on their resistance to blast, radiation, and missile hazards. The four structures received actual air overpressures of 56, 124, and 199 psi and suffered only minor damage, all remaining structurally serviceable. The entranceway used for the structures sealed out the air pressure. It was not designed to attenuate radiation and thus did not provide adequate radiation protection for personnel. There were no missile and apparently no dust hazards in any ofmore » the structures. Results of the test indicate that an underground reinforced-concrete arch is an excellent structural shape for resisting the effects of a kiloton-range air burst. (C.H.)« less
Terahertz imaging devices and systems, and related methods, for detection of materials
Kotter, Dale K.
2016-11-15
Terahertz imaging devices may comprise a focal plane array including a substrate and a plurality of resonance elements. The plurality of resonance elements may comprise a conductive material coupled to the substrate. Each resonance element of the plurality of resonance elements may be configured to resonate and produce an output signal responsive to incident radiation having a frequency between about a 0.1 THz and 4 THz range. A method of detecting a hazardous material may comprise receiving incident radiation by a focal plane array having a plurality of discrete pixels including a resonance element configured to absorb the incident radiation at a resonant frequency in the THz, generating an output signal from each of the discrete pixels, and determining a presence of a hazardous material by interpreting spectral information from the output signal.
Biological Sterilization of Returned Mars Samples
NASA Technical Reports Server (NTRS)
Allen, C. C.; Albert, F. G.; Combie, J.; Bodnar, R. J.; Hamilton, V. E.; Jolliff, B. L.; Kuebler, K.; Wang, A.; Lindstrom, D. J.; Morris, P. A.
1999-01-01
Martian rock and soil, collected by robotic spacecraft, will be returned to terrestrial laboratories early in the next century. Current plans call for the samples to be immediately placed into biological containment and tested for signs of present or past life and biological hazards. It is recommended that "Controlled distribution of unsterilized materials from Mars should occur only if rigorous analyses determine that the materials do not constitute a biological hazard. If any portion of the sample is removed from containment prior to completion of these analyses it should first be sterilized." While sterilization of Mars samples may not be required, an acceptable method must be available before the samples are returned to Earth. The sterilization method should be capable of destroying a wide range of organisms with minimal effects on the geologic samples. A variety of biological sterilization techniques and materials are currently in use, including dry heat, high pressure steam, gases, plasmas and ionizing radiation. Gamma radiation is routinely used to inactivate viruses and destroy bacteria in medical research. Many commercial sterilizers use Co-60 , which emits gamma photons of 1.17 and 1.33 MeV. Absorbed doses of approximately 1 Mrad (10(exp 8) ergs/g) destroy most bacteria. This study investigates the effects of lethal doses of Co-60 gamma radiation on materials similar to those anticipated to be returned from Mars. The goals are to determine the gamma dose required to kill microorganisms in rock and soil samples and to determine the effects of gamma sterilization on the samples' isotopic, chemical and physical properties. Additional information is contained in the original extended abstract.
Increased Risk of Ischemic Stroke in Young Nasopharyngeal Carcinoma Patients
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lee, Ching-Chih; Department of Otolaryngology, Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan; Tumor Center, Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan
Purpose: Radiation/chemoradiotherapy-induced carotid stenosis and cerebrovascular events in patients with nasopharyngeal carcinoma (NPC) can cause severe disability and even death. This study aimed to estimate the risk of ischemic stroke in this patient population over more than 10 years of follow-up. Methods and Materials: The study cohorts consisted of all patients hospitalized with a principal diagnosis of NPC (n = 1094), whereas patients hospitalized for an appendectomy during 1997 and 1998 (n = 4376) acted as the control group and surrogate for the general population. Cox proportional hazard model was performed as a means of comparing the stroke-free survival ratemore » between the two cohorts after adjusting for possible confounding and risk factors. Results: Of the 292 patients with ischemic strokes, 62 (5.7%) were from the NPC cohort and 230 (5.3%) were from the control group. NPC patients ages 35-54 had a 1.66 times (95% CI, 1.16-2.86; p = 0.009) higher risk of ischemic stroke after adjusting for patient characteristics, comorbidities, geographic region, urbanization level of residence, and socioeconomic status. There was no statistical difference in ischemic stroke risk between the NPC patients and appendectomy patients ages 55-64 years (hazard ratio = 0.87; 95% CI, 0.56-1.33; p = 0.524) after adjusting for other factors. Conclusions: Young NPC patients carry a higher risk for ischemic stroke than the general population. Besides regular examinations of carotid duplex, different irradiation strategies or using new technique of radiotherapy, such as intensity modulated radiation therapy or volumetric modulated arc therapy, should be considered in young NPC patients.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
VanderWalde, Noam A.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Meyer, Anne Marie
Purpose: The purpose of this study was to compare chemoradiation therapy (CRT) with radiation therapy (RT) only in an older patient population with head and neck squamous cell carcinoma (HNSCC). Methods and Materials: Using the Surveillance, Epidemiology, and End Results (SEER)-Medicare linked database (1992-2007), we identified a retrospective cohort of nonmetastatic HNSCC patients and divided them into treatment groups. Comparisons were made between CRT and RT cohorts. Propensity scores for CRT were estimated from covariates associated with receipt of treatment using multivariable logistic regression. Standardized mortality ratio weights (SMRW) were created from the propensity scores and used to balance groupsmore » on measured confounders. Multivariable and SMR-weighted Cox proportional hazard models were used to estimate the hazard ratio (HR) of death for receipt of CRT versus RT among the whole group and for separate patient and tumor categories. Results: The final cohort of 10,599 patients was 68% male and 89% white. Median age was 74 years. Seventy-four percent were treated with RT, 26% were treated with CRT. Median follow-up points for CRT and RT survivors were 4.6 and 6.3 years, respectively. On multivariable analysis, HR for death with CRT was 1.13 (95% confidence interval [CI]: 1.07-1.20; P<.01). Using the SMRW model, the HR for death with CRT was 1.08 (95% CI: 1.02-1.15; P=.01). Conclusions: Although the addition of chemotherapy to radiation has proven efficacious in many randomized controlled trials, it may be less effective in an older patient population treated outside of a controlled trial setting.« less
Ebaid, Y Y; Bakr, W F
2012-09-01
The aim of this study was to comprehensively study the radiological hazards of granite and marble used as a building material in Egypt. The activity concentrations of (226)Ra, (232)Th and (40)K were determined using high-resolution hyper-pure germanium detectors in 25 samples of different types of commercially available granite and marble. The measured activity concentrations for these natural radionuclides were compared with the reported data for Egypt and other countries. In order to assess the radiological impact, the radiation hazard parameters such as radium equivalent activity (Ra(eq)) and hazard level index (I(γ)) were calculated. The internal and external dose rates due to natural radionuclides in granite and marble were also calculated. The data obtained were considered as helpful in regulating the use of building materials in Egypt.
DETERMINATION OF MAXIMUM PERMISSIBLE LEAKAGE FROM THE HRT PROCESS STEAM SYSTEM
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gift, E.H.
1959-01-30
Calculations were made to determine the radiation hazard to HRT personnel as a result of leakage to the atmosphere from the process steam system in the event of a heat exchanger tube rupture. These calculations show that with the present four-minute delay before dumping approximately 1020 lb of fuel solution may be transferred to the steam system. The radiation hazard from fission products in the atomosphere will be negligble if the steam killer blower is operating. If this blower is not operatin. a natural convection loop will be set up in the steam killer which will have a condensing capacitymore » of 4 lb/min of steam at atmospheric pressure. In this latter case. the inhalation hazard will be negligible when the leak rate through the steam stop valves is less than 4lb/ min. (auth)« less
Nevada National Security Site Radiological Control Manual
DOE Office of Scientific and Technical Information (OSTI.GOV)
Radiological Control Managers’ Council
2012-03-26
This document supersedes DOE/NV/25946--801, 'Nevada Test Site Radiological Control Manual,' Revision 1 issued in February 2010. Brief Description of Revision: A complete revision to reflect a recent change in name for the NTS; changes in name for some tenant organizations; and to update references to current DOE policies, orders, and guidance documents. Article 237.2 was deleted. Appendix 3B was updated. Article 411.2 was modified. Article 422 was re-written to reflect the wording of DOE O 458.1. Article 431.6.d was modified. The glossary was updated. This manual contains the radiological control requirements to be used for all radiological activities conducted bymore » programs under the purview of the U.S. Department of Energy (DOE) and the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office (NNSA/NSO). Compliance with these requirements will ensure compliance with Title 10 Code of Federal Regulations (CFR) Part 835, 'Occupational Radiation Protection.' Programs covered by this manual are located at the Nevada National Security Site (NNSS); Nellis Air Force Base and North Las Vegas, Nevada; Santa Barbara and Livermore, California; and Andrews Air Force Base, Maryland. In addition, fieldwork by NNSA/NSO at other locations is covered by this manual. Current activities at NNSS include operating low-level radioactive and mixed waste disposal facilities for United States defense-generated waste, assembly and execution of subcritical experiments, assembly/disassembly of special experiments, the storage and use of special nuclear materials, performing criticality experiments, emergency responder training, surface cleanup and site characterization of contaminated land areas, environmental activity by the University system, and nonnuclear test operations, such as controlled spills of hazardous materials at the Hazardous Materials Spill Center. Currently, the major potential for occupational radiation exposure is associated with the burial of low-level radioactive waste and the handling of radioactive sources. Remediation of contaminated land areas may also result in radiological exposures.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Russo, Andrea L.; Adams, Judith A.; Weyman, Elizabeth A.
Purpose: Squamous cell carcinoma (SCC) is the most common sinonasal cancer and is associated with one of the poor outcomes. Proton therapy allows excellent target coverage with maximal sparing of adjacent normal tissues. We evaluated the long-term outcomes in patients with sinonasal SCC treated with proton therapy. Methods and Materials: Between 1991 and 2008, 54 patients with Stage III and IV SCC of the nasal cavity and paranasal sinus received proton beam therapy at our institution to a median dose of 72.8 Gy(RBE). Sixty-nine percent underwent prior surgical resection, and 74% received elective nodal radiation. Locoregional control and survival probabilities weremore » estimated with the Kaplan-Meier method. Multivariate analyses were performed using the Cox proportional-hazards model. Treatment toxicity was scored using the Common Terminology Criteria for Adverse Events version 4.0. Results: With a median follow-up time of 82 months in surviving patients, there were 10 local, 7 regional, and 11 distant failures. The 2-year and 5-year actuarial local control rate was 80%. The 2-year and 5-year rates of overall survival were 67% and 47%, respectively. Only smoking status was predictive for worse locoregional control, with current smokers having a 5-year rate of 23% compared with 83% for noncurrent smokers (P=.004). Karnofsky performance status ≤80 was the most significant factor predictive for worse overall survival in multivariate analysis (adjusted hazard ratio 4.5, 95% confidence interval 1.6-12.5, P=.004). There were nine grade 3 and six grade 4 toxicities, and no grade 5 toxicity. Wound adverse events constituted the most common grade 3-4 toxicity. Conclusions: Our long-term results show that proton radiation therapy is well tolerated and yields good locoregional control for SCC of the nasal cavity and paranasal sinus. Current smokers and patients with poor performance status had inferior outcomes. Prospective study is necessary to compare IMRT with proton therapy in the treatment of sinonasal malignancy.« less
Calfee, Robin D.; Little, Edward E.; Pearl, Christopher A.; Hoffman, Robert L.
2010-01-01
Solar ultraviolet radiation (UV) has received much attention as a factor that could play a role in amphibian population declines. UV can be hazardous to some amphibians, but the resultant effects depend on a variety of environmental and behavioral factors. In this study, the potential effects of UV on the Northwestern Salamander, Ambystoma gracile, from three lakes were assessed in the laboratory using a solar simulator. We measured the survival of embryos and the survival and growth of larvae exposed to four UV treatments in controlled laboratory studies, the UV absorbance of egg jelly, oviposition depths in the lakes, and UV absorbance in water samples from the three lakes. Hatching success of embryos decreased in the higher UV treatments as compared to the control treatments, and growth of surviving larvae was significantly reduced in the higher UVB irradiance treatments. The egg jelly exhibited a small peak of absorbance within the UVB range (290–320 nm). The magnitude of UV absorbance differed among egg jellies from the three lakes. Oviposition depths at the three sites averaged 1.10 m below the water surface. Approximately 66% of surface UVB radiation was attenuated at 10-cm depth in all three lakes. Results of this study indicate that larvae may be sensitive to UVB exposure under laboratory conditions; however, in field conditions the depths of egg deposition in the lakes, absorbance of UV radiation by the water column, and the potential for behavioral adjustments may mitigate severe effects of UV radiation.
Calfee, R.D.; Little, E.E.; Pearl, C.A.; Hoffman, R.L.
2010-01-01
Solar ultraviolet radiation (UV) has received much attention as a factor that could play a role in amphibian population declines. UV can be hazardous to some amphibians, but the resultant effects depend on a variety of environmental and behavioral factors. In this study, the potential effects of UV on the Northwestern Salamander, Ambystoma gracile, from three lakes were assessed in the laboratory using a solar simulator. We measured the survival of embryos and the survival and growth of larvae exposed to four UV treatments in controlled laboratory studies, the UV absorbance of egg jelly, oviposition depths in the lakes, and UV absorbance in water samples from the three lakes. Hatching success of embryos decreased in the higher UV treatments as compared to the control treatments, and growth of surviving larvae was significantly reduced in the higher UVB irradiance treatments. The egg jelly exhibited a small peak of absorbance within the UVB range (290-320 nm). The magnitude of UV absorbance differed among egg jellies from the three lakes. Oviposition depths at the three sites averaged 1.10 m below the water surface. Approximately 66 of surface UVB radiation was attenuated at 10-cm depth in all three lakes. Results of this study indicate that larvae may be sensitive to UVB exposure under laboratory conditions; however, in field conditions the depths of egg deposition in the lakes, absorbance of UV radiation by the water column, and the potential for behavioral adjustments may mitigate severe effects of UV radiation. Copyright 2010 Society for the Study of Amphibians and Reptiles.
Hazards to space workers from ionizing radiation
NASA Technical Reports Server (NTRS)
Lyman, J. T.
1980-01-01
A compilation of background information and a preliminary assessment of the potential risks to workers from the ionizing radiation encountered in space is provided. The report: (1) summarizes the current knowledge of the space radiation environment to which space workers will be exposed; (2) reviews the biological effects of ionizing radiation considered of major importance to a SPS project; and (3) discusses the health implications of exposure of populations of space workers to the radiations likely to penetrate through the shielding provided by the SPS work stations and habitat shelters of the SPS Reference System.
42 CFR 75.1 - Background and purpose.
Code of Federal Regulations, 2010 CFR
2010-10-01
...) radiographer, (2) dental hygienist, (3) dental assistant, (4) nuclear medicine technologist, and (5) radiation therapy technologist. In the interest of public safety and to prevent the hazards of improper use of medical radiation identified by Congress in its determination of the need for standards, the Secretary is...
42 CFR 75.1 - Background and purpose.
Code of Federal Regulations, 2014 CFR
2014-10-01
...) radiographer, (2) dental hygienist, (3) dental assistant, (4) nuclear medicine technologist, and (5) radiation therapy technologist. In the interest of public safety and to prevent the hazards of improper use of medical radiation identified by Congress in its determination of the need for standards, the Secretary is...
42 CFR 75.1 - Background and purpose.
Code of Federal Regulations, 2012 CFR
2012-10-01
...) radiographer, (2) dental hygienist, (3) dental assistant, (4) nuclear medicine technologist, and (5) radiation therapy technologist. In the interest of public safety and to prevent the hazards of improper use of medical radiation identified by Congress in its determination of the need for standards, the Secretary is...
42 CFR 75.1 - Background and purpose.
Code of Federal Regulations, 2013 CFR
2013-10-01
...) radiographer, (2) dental hygienist, (3) dental assistant, (4) nuclear medicine technologist, and (5) radiation therapy technologist. In the interest of public safety and to prevent the hazards of improper use of medical radiation identified by Congress in its determination of the need for standards, the Secretary is...
42 CFR 75.1 - Background and purpose.
Code of Federal Regulations, 2011 CFR
2011-10-01
...) radiographer, (2) dental hygienist, (3) dental assistant, (4) nuclear medicine technologist, and (5) radiation therapy technologist. In the interest of public safety and to prevent the hazards of improper use of medical radiation identified by Congress in its determination of the need for standards, the Secretary is...
Yokota, Kenichi; Mine, Mariko; Kondo, Hisayoshi; Matsuda, Naoki; Shibata, Yoshisada; Takamura, Noboru
2018-01-01
The health effects of radiation exposure from the atomic bomb fallout remain unclear. The objective of the present study is to elucidate the association between low-dose radiation exposure from the atomic bomb fallout and cancer mortality among Nagasaki atomic bomb survivors. Of 77 884 members in the Nagasaki University Atomic Bomb Survivors Cohort, 610 residents in the terrain-shielded area with fallout were selected for this analysis; 1443 residents in the terrain-shielded area without fallout were selected as a control group; and 3194 residents in the direct exposure area were also selected for study. Fifty-two deaths due to cancer in the terrain-shielded fallout area were observed during the follow-up period from 1 January 1970 to 31 December 2012. The hazard ratio for cancer mortality in the terrain-shielded fallout area was 0.90 (95% confidence interval: 0.65-1.24). No increase in the risk of cancer mortality was observed, probably because the dose of the radiation exposure was low for residents in the terrain-shielded fallout areas of the Nagasaki atomic bomb, and also because the number of study subjects was small. © The Author 2017. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Radiation Oncology.
Occupational health hazards in the interventional laboratory: Time for a safer environment.
Klein, Lloyd W; Miller, Donald L; Balter, Stephen; Laskey, Warren; Naito, Neil; Haines, David; Ross, Allan; Mauro, Matthew A; Goldstein, James A
2018-01-04
Over the past 30 years, the advent of fluoroscopically guided interventional procedures has resulted in dramatic increments in both X-ray exposure and physical demands that predispose interventionists to distinct occupational health hazards. The hazards of accumulated radiation exposure have been known for years, but until recently the other potential risks have been ill-defined and under-appreciated. The physical stresses inherent in this career choice appear to be associated with a predilection to orthopedic injuries, attributable in great part to the cumulative adverse effects of bearing the weight and design of personal protective apparel worn to reduce radiation risk and to the poor ergonomic design of interventional suites. These occupational health concerns pertain to cardiologists, radiologists and surgeons working with fluoroscopy, pain management specialists performing nonvascular fluoroscopic procedures, and the many support personnel working in these environments. This position paper is the work of representatives of the major societies of physicians who work in the interventional laboratory environment, and has been formally endorsed by all. In this paper, the available data delineating the prevalence of these occupational health risks is reviewed and ongoing epidemiological studies designed to further elucidate these risks are summarized. The main purpose is to publicly state speaking with a single voice that the interventional laboratory poses workplace hazards that must be acknowledged, better understood and mitigated to the greatest extent possible, and to advocate vigorously on behalf of efforts to reduce these hazards. Interventional physicians and their professional societies, working together with industry, should strive toward the ultimate zero radiation exposure work environment that would eliminate the need for personal protective apparel and prevent its orthopedic and ergonomic consequences. © 2008 Wiley-Liss, Inc. Copyright © 2008 Wiley‐Liss, Inc.
Development of a numerical model to predict physiological strain of firefighter in fire hazard.
Su, Yun; Yang, Jie; Song, Guowen; Li, Rui; Xiang, Chunhui; Li, Jun
2018-02-26
This paper aims to develop a numerical model to predict heat stress of firefighter under low-level thermal radiation. The model integrated a modified multi-layer clothing model with a human thermoregulation model. We took the coupled radiative and conductive heat transfer in the clothing, the size-dependent heat transfer in the air gaps, and the controlling active and controlled passive thermal regulation in human body into consideration. The predicted core temperature and mean skin temperature from the model showed a good agreement with the experimental results. Parametric study was conducted and the result demonstrated that the radiative intensity had a significant influence on the physiological heat strain. The existence of air gap showed positive effect on the physiological heat strain when air gap size is small. However, when the size of air gap exceeds 6 mm, a different trend was observed due to the occurrence of natural convection. Additionally, the time length for the existence of the physiological heat strain was greater than the existence of the skin burn under various heat exposures. The findings obtained in this study provide a better understanding of the physiological strain of firefighter and shed light on textile material engineering for achieving higher protective performance.
Long-term outcome of patients treated by radiation therapy alone for salivary gland carcinomas
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chen, Allen M.; Bucci, M. Kara; Quivey, Jeanne M.
2006-11-15
Purpose: To review a single-institution experience with the management of salivary gland cancers treated by radiation alone. Methods and Materials: Between 1960 and 2004, 45 patients with newly diagnosed salivary gland carcinomas were treated with definitive radiation to a median dose of 66 Gy (range, 57-74 Gy). Distribution of T-stage was: 24% T1, 18% T2, 31% T3, and 27% T4. Histology was: 14 mucoepidermoid (31%), 10 adenocarcinoma (22%), 8 adenoid cystic (18%), 4 undifferentiated (9%), 4 acinic (9%), 2 malignant mixed (4%), 2 squamous (4%), and 1 salivary duct carcinoma (2%). No patient had clinical or pathologic evidence of lymphmore » node disease. Median follow-up was 101 months (range, 3-285 months). Results: The 5-year and 10-year rate estimates of local control were 70% and 57%, respectively. A Cox proportional hazard model identified T3-4 disease (p = 0.004) and radiation dose lower than 66 Gy (p = 0.001) as independent predictors of local recurrence. The 10-year overall survival and distant metastasis-free rates were 46% and 67%, respectively. Conclusion: Radiation therapy alone is a reasonable alternative to surgery in the definitive management of salivary gland cancers and results in long-term survival in a significant proportion of patients. Radiation dose in excess of 66 Gy is recommended.« less
21 CFR 123.6 - Hazard analysis and Hazard Analysis Critical Control Point (HACCP) plan.
Code of Federal Regulations, 2013 CFR
2013-04-01
... identified food safety hazards, including as appropriate: (i) Critical control points designed to control... control points designed to control food safety hazards introduced outside the processing plant environment... Control Point (HACCP) plan. 123.6 Section 123.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF...
21 CFR 123.6 - Hazard analysis and Hazard Analysis Critical Control Point (HACCP) plan.
Code of Federal Regulations, 2011 CFR
2011-04-01
... identified food safety hazards, including as appropriate: (i) Critical control points designed to control... control points designed to control food safety hazards introduced outside the processing plant environment... Control Point (HACCP) plan. 123.6 Section 123.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF...
21 CFR 123.6 - Hazard analysis and Hazard Analysis Critical Control Point (HACCP) plan.
Code of Federal Regulations, 2014 CFR
2014-04-01
... identified food safety hazards, including as appropriate: (i) Critical control points designed to control... control points designed to control food safety hazards introduced outside the processing plant environment... Control Point (HACCP) plan. 123.6 Section 123.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF...
Radiation dosimetry for the Gemini program
NASA Technical Reports Server (NTRS)
Richmond, R. G.
1972-01-01
The principal source of radiation for low-earth-orbit, low inclination space flights is in the area of the South Atlantic magnetic anomaly. None of the Gemini dose measurements reported in the paper are of high enough intensity to be considered hazardous. There is a trend toward larger doses as missions are flown higher and longer. Extended orbital operations between 1400 and 4400 kilometers would encounter high interior radiation levels. Pronounced spacecraft geometry effects have been measured in manned spacecraft. Instrumentation for radiation measurements on Gemini spacecraft is described.
1993-10-01
brimmed hats can help prevent sunburn. Chronic exposure to UV radiation is known to cause skin cancer. In case of sunburn, do not apply burn ointment ...personnel who have the potential to be exposed to hazardous or toxic substances or environments during the course of field activities. Each member of the...investigations who are exposed or potentially exposed to hazardous substances or health hazards at or above the established exposure levels for these substances
NASA Technical Reports Server (NTRS)
Morgan, William F.
2003-01-01
A long-standing dogma in the radiation sciences is that energy from radiation must be deposited in the cell nucleus to elicit a biological effect. A number of non-targeted, delayed effects of ionizing radiation have been described that challenge this dogma and pose new challenges to evaluating potential hazards associated with radiation exposure. These effects include induced genomic instability and non-targeted bystander effects. The in vitro evidence for non-targeted effects in radiation biology will be reviewed, but the question as to how one extrapolates from these in vitro observations to the risk of radiation-induced adverse health effects such as cancer remains open.
Radiation Hardness Assurance (RHA) for Small Missions
NASA Technical Reports Server (NTRS)
Campola, Michael J.
2016-01-01
Varied mission life and complexity is growing for small spacecraft. Small missions benefit from detailed hazard definition and evaluation as done in the past. Requirements need to flow from the system down to the parts level and aid system level radiation tolerance. RHA is highlighted with increasing COTS usage.
In Vitro Phototoxicity and Hazard Identification of Nano-scale Titanium Dioxide
Nano-titanium dioxide (nano-Ti02) catalyzes many reactions under UV radiation and is hypothesized to cause phototoxicity. A human-derived line of retinal pigment epithelial cells (ARPE-19) was treated with six different samples of nano-Ti02 and exposed to UVA radiation. The Ti02 ...
Stroke After Radiation Therapy for Head and Neck Cancer: What Is the Risk?
DOE Office of Scientific and Technical Information (OSTI.GOV)
Arthurs, Erin; Hanna, Timothy P.; Department of Oncology, Queen's University, Kingston, Ontario
Purpose: A retrospective population-based cohort study was conducted to determine the risk of ischemic stroke with respect to time, associated with curative radiation therapy in head and neck squamous cell carcinomas (HNSCC). Methods and Materials: On the basis of data from the Ontario Cancer Registry and regional cancer treatment centers, 14,069 patients were identified with diagnoses of squamous cell carcinoma of the oral cavity, larynx, and pharynx who were treated for cure between 1990 and 2010. Hazards of stroke and time to stroke were examined, accounting for the competing risk of death. Stroke risk factors identified through diagnostic and proceduralmore » administrative codes were adjusted for in the comparison between treatment regimens, which included surgery alone versus radiation therapy alone and surgery alone versus any exposure to radiation therapy. Results: Overall, 6% of patients experienced an ischemic stroke after treatment, with 5% experiencing a stroke after surgery, 8% after radiation therapy alone, and 6% after any exposure to radiation therapy. The cause-specific hazard ratios of ischemic stroke after radiation therapy alone and after any exposure to radiation therapy compared with surgery were 1.70 (95% confidence interval [CI]: 1.41-2.05) and 1.46 (95% CI: 1.23-1.73), respectively, after adjustment for stroke risk factors, patient factors, and disease-related factors. Conclusions: Radiation therapy was associated with an increased risk of ischemic stroke compared with surgery alone: for both radiation therapy alone and after all treatment modalities that included any radiation treatment were combined. Because of a shift toward a younger HNSCC patient population, our results speak to the need for adequate follow-up and survivorship care among patients who have been treated with radiation therapy. Advances in treatment that minimize chronic morbidity also require further evaluation.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mueller, Sabine, E-mail: muellers@neuropeds.ucsf.edu; Fullerton, Heather J.; Stratton, Kayla
Purpose: To test the hypotheses that (1) the increased risk of stroke conferred by childhood cranial radiation therapy (CRT) persists into adulthood; and (2) atherosclerotic risk factors further increase the stroke risk in cancer survivors. Methods and Materials: The Childhood Cancer Survivor Study is a multi-institutional retrospective cohort study of 14,358 5-year survivors of childhood cancer and 4023 randomly selected sibling controls with longitudinal follow-up. Age-adjusted incidence rates of self-reported late-occurring (≥5 years after diagnosis) first stroke were calculated. Multivariable Cox proportional hazards models were used to identify independent stroke predictors. Results: During a mean follow-up of 23.3 years, 292more » survivors reported a late-occurring stroke. The age-adjusted stroke rate per 100,000 person-years was 77 (95% confidence interval [CI] 62-96), compared with 9.3 (95% CI 4-23) for siblings. Treatment with CRT increased stroke risk in a dose-dependent manner: hazard ratio 5.9 (95% CI 3.5-9.9) for 30-49 Gy CRT and 11.0 (7.4-17.0) for 50+ Gy CRT. The cumulative stroke incidence in survivors treated with 50+ Gy CRT was 1.1% (95% CI 0.4-1.8%) at 10 years after diagnosis and 12% (95% CI 8.9-15.0%) at 30 years. Hypertension increased stroke hazard by 4-fold (95% CI 2.8-5.5) and in black survivors by 16-fold (95% CI 6.9-36.6). Conclusion: Young adult pediatric cancer survivors have an increased stroke risk that is associated with CRT in a dose-dependent manner. Atherosclerotic risk factors enhanced this risk and should be treated aggressively.« less
Zou, Yan; Song, Tao; Yu, Wei; Zhao, Ruping; Wang, Yong; Xie, Ruifei; Chen, Tian; Wu, Bo; Wu, Shixiu
2014-03-01
The incidence of radiation-induced late xerostomia varies greatly in nasopharyngeal carcinoma patients treated with radiotherapy. The single-nucleotide polymorphisms in genes involved in DNA repair and fibroblast proliferation may be correlated with such variability. The purpose of this paper was to evaluate the association between the risk of developing radiation-induced late xerostomia and four genetic polymorphisms: TGFβ1 C-509T, TGFβ1 T869C, XRCC3 722C>T and ATM 5557G>A in nasopharyngeal carcinoma patients treated with Intensity Modulation Radiated Therapy. The severity of late xerostomia was assessed using a patient self-reported validated xerostomia questionnaire. Polymerase chain reaction-ligation detection reaction methods were performed to determine individual genetic polymorphism. The development of radiation-induced xerostomia associated with genetic polymorphisms was modeled using Cox proportional hazards, accounting for equivalent uniform dose. A total of 43 (41.7%) patients experienced radiation-induced late xerostomia. Univariate Cox proportional hazard analyses showed a higher risk of late xerostomia for patients with XRCC3 722 TT/CT alleles. In multivariate analysis adjusted for clinical and dosimetric factors, XRCC3 722C>T polymorphisms remained a significant factor for higher risk of late xerostomia. To our knowledge, this is the first study that demonstrated an association between genetic polymorphisms and the risk of radiation-induced late xerostomia in nasopharyngeal carcinoma patients treated with Intensity Modulation Radiated Therapy. Our findings suggest that the polymorphisms in XRCC3 are significantly associated with the risk of developing radiation-induced late xerostomia.
Radiation hazards in scoliosis management
DOE Office of Scientific and Technical Information (OSTI.GOV)
Drummond, D.; Ranallo, F.; Lonstein, J.
1983-10-01
Safe radiography in scoliosis management is based on a sound knowledge of 1) the radiographic imaging process, 2) the degree of risk to the patient from radiation exposure, and 3) the radiographic requirements to both evaluate and follow patients with spine deformity. This paper is a current review of the subject and work done at the authors' centers. It includes recommendations for reducing the radiation risk while maintaining necessary diagnostic information.
HAZARDS SUMMARY REPORT FOR A TWO WATT PROMETHIUM-147 FUELED THERMOELECTRIC GENERATOR
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
1959-06-01
Discussions are included of the APU design, vehicle integration, Pm/sup 147/ properties, shielding requirements, hazards design criteria, statistical analysis for impact, and radiation protection. The use of Pm/sup 147/ makes possible the fabrication of an auxiliary power unit which has applications for low power space missions of <10 watts (electrical). (B.O.G.)
Exploring the Feasibility of Electrostatic Shielding for Spacecrafts
NASA Technical Reports Server (NTRS)
Tripathi, R. K.; Wilson, J. W.; Youngquist, R. C.
2005-01-01
NASA is moving forward towards the agency's new vision for space exploration in the 21st Century encompassing a broad range of human and robotic missions including missions to Moon, Mars and beyond. Exposure from the hazards of severe space radiation in deep space long duration missions is the show stopper. Langley has developed state-of-the-art radiation protection and shielding technology for space missions. The payload penalty demands a very stringent requirement on the design of the spacecrafts for human deep space missions. The exploration beyond low Earth orbit (LEO) to enable routine access to more interesting regions of space will require protection from the hazards of the accumulated exposures of space radiation, Galactic Cosmic Rays (GCR) and Solar Particle Events (SPE), and minimizing the production of secondary radiation is a great advantage. There is a need to look to new horizons for newer technologies. The present investigation explores the feasibility of using electrostatic shielding in concert with innovative materials shielding and protection technologies. The asymmetries of the radiation shielding problem would be exploited in the electrostatics shielding process. The goal is to repel enough positive charge ions so that they miss the spacecraft without attracting thermal electrons. Conclusions are drawn about the advantages the electrostatic shielding, should it be successful, would bring to the radiation protection design process.
NASA Astrophysics Data System (ADS)
Joyce, C. J.; Tobiska, W. K.; Copeland, K.; Smart, D. F.; Shea, M. A.; Nowicki, S.; Atwell, W.; Benton, E. R.; Wilkins, R.; Hands, A.; Gronoff, G.; Meier, M. M.; Schwadron, N.
2017-12-01
Despite its potential for causing a wide range of harmful effects, including health hazards to airline passengers and damage to aircraft and satellite electronics, atmospheric radiation remains a relatively poorly defined risk, lacking sufficient measurements and modelling to fully evaluate the dangers posed. While our reliance on airline travel has increased dramatically over time, there remains an absence of international guidance and standards to protect aircraft passengers from potential health impacts due to radiation exposure. This subject has been gaining traction within the scientific community in recent years, with an expanding number of models with increasing capabilities being made available to evaluate atmospheric radiation hazards. We provide a general description of these modelling efforts, including the physics and methods used by the models, as well as their data inputs and outputs. We also discuss the current capacity for model validation via measurements and discuss the needs for the next generation of models, both in terms of their capabilities and the measurements required to validate them. This review of the status of atmospheric radiation modelling is part of a larger series of studies made as part of the SAFESKY program, with other efforts focusing on the underlying physics and implications, measurements and regulations/standards of atmospheric radiation.
Witthöft, Michael; Freitag, Ina; Nußbaum, Christiane; Bräscher, Anne-Kathrin; Jasper, Fabian; Bailer, Josef; Rubin, G James
2018-03-01
Worries about health threatening effects of potential health hazards of modern life (e.g. electric devices and pollution) represent a growing phenomenon in Western countries. Yet, little is known about the causes of this growing special case of affective risk perceptions termed Modern Health Worries (MHW). The purpose of this study is to examine a possible role of biased media reports in the formation of MHW. In two experiments, we investigated whether typical television reports affect MHW. In Study 1, 130 participants were randomly assigned to a film on idiopathic environmental intolerance (IEI) or a control film about cystic fibrosis. In Study 2, 82 participants were randomly assigned to either a film on the dangers of electromagnetic fields or a control condition. Increases in MHW after sensational media reports. In Study 1, only participants high on the personality trait of absorption revealed increased MHW after watching the IEI film. In Study 2, specifically worries about radiation were found to be elevated after watching the film on the dangers of electromagnetic fields compared to the control film. The results of both studies reveal a significant and specific influence of sensational short mass media reports on MHW. The influence of potential moderators such as absorption remains to be clarified.
Examination system utilizing ionizing radiation and a flexible, miniature radiation detector probe
Majewski, S.; Kross, B.J.; Zorn, C.J.; Majewski, L.A.
1996-10-22
An optimized examination system and method based on the Reverse Geometry X-Ray{trademark} (RGX{trademark}) radiography technique are presented. The examination system comprises a radiation source, at least one flexible, miniature radiation detector probe positioned in appropriate proximity to the object to be examined and to the radiation source with the object located between the source and the probe, a photodetector device attachable to an end of the miniature radiation probe, and a control unit integrated with a display device connected to the photodetector device. The miniature radiation detector probe comprises a scintillation element, a flexible light guide having a first end optically coupled to the scintillation element and having a second end attachable to the photodetector device, and an opaque, environmentally-resistant sheath surrounding the flexible light guide. The probe may be portable and insertable, or may be fixed in place within the object to be examined. An enclosed, flexible, liquid light guide is also presented, which comprises a thin-walled flexible tube, a liquid, preferably mineral oil, contained within the tube, a scintillation element located at a first end of the tube, closures located at both ends of the tube, and an opaque, environmentally-resistant sheath surrounding the flexible tube. The examination system and method have applications in non-destructive material testing for voids, cracks, and corrosion, and may be used in areas containing hazardous materials. In addition, the system and method have applications for medical and dental imaging. 5 figs.
Examination system utilizing ionizing radiation and a flexible, miniature radiation detector probe
Majewski, Stanislaw; Kross, Brian J.; Zorn, Carl J.; Majewski, Lukasz A.
1996-01-01
An optimized examination system and method based on the Reverse Geometry X-Ray.RTM. (RGX.RTM.) radiography technique are presented. The examination system comprises a radiation source, at least one flexible, miniature radiation detector probe positioned in appropriate proximity to the object to be examined and to the radiation source with the object located between the source and the probe, a photodetector device attachable to an end of the miniature radiation probe, and a control unit integrated with a display device connected to the photodetector device. The miniature radiation detector probe comprises a scintillation element, a flexible light guide having a first end optically coupled to the scintillation element and having a second end attachable to the photodetector device, and an opaque, environmentally-resistant sheath surrounding the flexible light guide. The probe may be portable and insertable, or may be fixed in place within the object to be examined. An enclosed, flexible, liquid light guide is also presented, which comprises a thin-walled flexible tube, a liquid, preferably mineral oil, contained within the tube, a scintillation element located at a first end of the tube, closures located at both ends of the tube, and an opaque, environmentally-resistant sheath surrounding the flexible tube. The examination system and method have applications in non-destructive material testing for voids, cracks, and corrosion, and may be used in areas containing hazardous materials. In addition, the system and method have applications for medical and dental imaging.
ICBMs and the environment: Assessments at a base in Kazakhstan
Matzko, J.R.; Butler, B.
1999-01-01
A paper by two U.S. scientists explores the environmental/health hazard posed by abandoned missile launch sites and control facilities (dismantled by 1998 as part of the Nunn-Lugar Cooperative Threat Reduction Program) at an ICBM base in north-central Kazakhstan. It summarizes the findings of Environmental Site Assessment Reports based on a program of water and soil sampling at the sites, with a particular focus on testing for the presence of polychlorinated biphenyls, various toxic metals, and radiation. The study is important in that it documents levels of contamination (and describes abatement measures) at a former Soviet missile base.
NASA Technical Reports Server (NTRS)
Tripathi, Ram K.; Nealy, John E.
2007-01-01
NASA is now focused on the agency's vision for space exploration encompassing a broad range of human and robotic missions including missions to Moon, Mars and beyond. As a result, there is a focus on long duration space missions. NASA is committed to the safety of the missions and the crew, and there is an overwhelming emphasis on the reliability issues for space missions and the habitat. The cost-effective design of the spacecraft demands a very stringent requirement on the optimization process. Exposure from the hazards of severe space radiation in deep space and/or long duration missions is a critical design constraint and a potential 'show stopper'. Thus, protection from the hazards of severe space radiation is of paramount importance to the agency's vision. It is envisioned to have long duration human presence on the Moon for deep space exploration. The exposures from ionizing radiation - galactic cosmic radiation and solar particle events - and optimized shield design for a swing-by and a long duration Mars mission have been investigated. It is found that the technology of today is inadequate for safe human missions to Mars, and revolutionary technologies need to be developed for long duration and/or deep space missions. The study will provide a guideline for radiation exposure and protection for long duration missions and career astronauts and their safety.
NASA Astrophysics Data System (ADS)
Vannitsen, J.; Segret, B.; Miau, J. J.; Juang, J.-C.
2013-09-01
In order to prepare the Human Mission to Mars, few aspects of the mission still have to be known. During a transit to the Red Planet, future crews will be exposed to potentially hazardous radiations [1]. By using a CubeSat, we can then have a relatively cheap and easy way to improve the radiations environment knowledge for a Mars manned mission. A 1 Unit CubeSat is a type of miniaturized satellite for space research that usually has a volume of exactly one litre (10 cm cube), has a mass of no more than 1.33 kilograms and typically uses commercial off-the-shelf components for its electronics [2]. In this project, it is planned to use a 3 Unit CubeSat having the following dimensions: 10 cm x 10 cm x 30 cm and a maximum mass of 4kg.
EPA Facility Registry Service (FRS): Facility Interests Dataset - Intranet
This web feature service consists of location and facility identification information from EPA's Facility Registry Service (FRS) for all sites that are available in the FRS individual feature layers. The layers comprise the FRS major program databases, including:Assessment Cleanup and Redevelopment Exchange System (ACRES) : brownfields sites ; Air Facility System (AFS) : stationary sources of air pollution ; Air Quality System (AQS) : ambient air pollution data from monitoring stations; Bureau of Indian Affairs (BIA) : schools data on Indian land; Base Realignment and Closure (BRAC) facilities; Clean Air Markets Division Business System (CAMDBS) : market-based air pollution control programs; Comprehensive Environmental Response, Compensation, and Liability Information System (CERCLIS) : hazardous waste sites; Integrated Compliance Information System (ICIS) : integrated enforcement and compliance information; National Compliance Database (NCDB) : Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Toxic Substances Control Act (TSCA); National Pollutant Discharge Elimination System (NPDES) module of ICIS : NPDES surface water permits; Radiation Information Database (RADINFO) : radiation and radioactivity facilities; RACT/BACT/LAER Clearinghouse (RBLC) : best available air pollution technology requirements; Resource Conservation and Recovery Act Information System (RCRAInfo) : tracks generators, transporters, treaters, storers, and disposers of haz
EPA Facility Registry Service (FRS): Facility Interests Dataset - Intranet Download
This downloadable data package consists of location and facility identification information from EPA's Facility Registry Service (FRS) for all sites that are available in the FRS individual feature layers. The layers comprise the FRS major program databases, including:Assessment Cleanup and Redevelopment Exchange System (ACRES) : brownfields sites ; Air Facility System (AFS) : stationary sources of air pollution ; Air Quality System (AQS) : ambient air pollution data from monitoring stations; Bureau of Indian Affairs (BIA) : schools data on Indian land; Base Realignment and Closure (BRAC) facilities; Clean Air Markets Division Business System (CAMDBS) : market-based air pollution control programs; Comprehensive Environmental Response, Compensation, and Liability Information System (CERCLIS) : hazardous waste sites; Integrated Compliance Information System (ICIS) : integrated enforcement and compliance information; National Compliance Database (NCDB) : Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Toxic Substances Control Act (TSCA); National Pollutant Discharge Elimination System (NPDES) module of ICIS : NPDES surface water permits; Radiation Information Database (RADINFO) : radiation and radioactivity facilities; RACT/BACT/LAER Clearinghouse (RBLC) : best available air pollution technology requirements; Resource Conservation and Recovery Act Information System (RCRAInfo) : tracks generators, transporters, treaters, storers, and disposers
EPA Facility Registry Service (FRS): Facility Interests Dataset Download
This downloadable data package consists of location and facility identification information from EPA's Facility Registry Service (FRS) for all sites that are available in the FRS individual feature layers. The layers comprise the FRS major program databases, including:Assessment Cleanup and Redevelopment Exchange System (ACRES) : brownfields sites ; Air Facility System (AFS) : stationary sources of air pollution ; Air Quality System (AQS) : ambient air pollution data from monitoring stations; Bureau of Indian Affairs (BIA) : schools data on Indian land; Base Realignment and Closure (BRAC) facilities; Clean Air Markets Division Business System (CAMDBS) : market-based air pollution control programs; Comprehensive Environmental Response, Compensation, and Liability Information System (CERCLIS) : hazardous waste sites; Integrated Compliance Information System (ICIS) : integrated enforcement and compliance information; National Compliance Database (NCDB) : Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Toxic Substances Control Act (TSCA); National Pollutant Discharge Elimination System (NPDES) module of ICIS : NPDES surface water permits; Radiation Information Database (RADINFO) : radiation and radioactivity facilities; RACT/BACT/LAER Clearinghouse (RBLC) : best available air pollution technology requirements; Resource Conservation and Recovery Act Information System (RCRAInfo) : tracks generators, transporters, treaters, storers, and disposers
EPA Facility Registry Service (FRS): Facility Interests Dataset
This web feature service consists of location and facility identification information from EPA's Facility Registry Service (FRS) for all sites that are available in the FRS individual feature layers. The layers comprise the FRS major program databases, including:Assessment Cleanup and Redevelopment Exchange System (ACRES) : brownfields sites ; Air Facility System (AFS) : stationary sources of air pollution ; Air Quality System (AQS) : ambient air pollution data from monitoring stations; Bureau of Indian Affairs (BIA) : schools data on Indian land; Base Realignment and Closure (BRAC) facilities; Clean Air Markets Division Business System (CAMDBS) : market-based air pollution control programs; Comprehensive Environmental Response, Compensation, and Liability Information System (CERCLIS) : hazardous waste sites; Integrated Compliance Information System (ICIS) : integrated enforcement and compliance information; National Compliance Database (NCDB) : Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Toxic Substances Control Act (TSCA); National Pollutant Discharge Elimination System (NPDES) module of ICIS : NPDES surface water permits; Radiation Information Database (RADINFO) : radiation and radioactivity facilities; RACT/BACT/LAER Clearinghouse (RBLC) : best available air pollution technology requirements; Resource Conservation and Recovery Act Information System (RCRAInfo) : tracks generators, transporters, treaters, storers, and disposers of haz
NASA Astrophysics Data System (ADS)
Peng, L.; Sheffield, J.; Li, D.
2015-12-01
Evapotranspiration (ET) is a key link between the availability of water resources and climate change and climate variability. Variability of ET has important environmental and socioeconomic implications for managing hydrological hazards, food and energy production. Although there have been many observational and modeling studies of ET, how ET has varied and the drivers of the variations at different temporal scales remain elusive. Much of the uncertainty comes from the atmospheric evaporative demand (AED), which is the combined effect of radiative and aerodynamic controls. The inconsistencies among modeled AED estimates and the limited observational data may originate from multiple sources including the limited time span and uncertainties in the data. To fully investigate and untangle the intertwined drivers of AED, we present a spectrum analysis to identify key controls of AED across multiple temporal scales. We use long-term records of observed pan evaporation for 1961-2006 from 317 weather stations across China and physically-based model estimates of potential evapotranspiration (PET). The model estimates are based on surface meteorology and radiation derived from reanalysis, satellite retrievals and station data. Our analyses show that temperature plays a dominant role in regulating variability of AED at the inter-annual scale. At the monthly and seasonal scales, the primary control of AED shifts from radiation in humid regions to humidity in dry regions. Unlike many studies focusing on the spatial pattern of ET drivers based on a traditional supply and demand framework, this study underlines the importance of temporal scales when discussing controls of ET variations.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-30
... Federal Register notice published on May 18, 2011 for Lead Based Paint Hazard Control and Lead Hazard... Based Paint Hazard Control Grant Program A total of $43,206,000 was awarded to 22 grantees for the Lead Based Paint Hazard Control Grant Program and an additional $1,999,971 was awarded to 20 out of the 29...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-30
... Federal Register notice published on September 9, 2010 for Lead Based Paint Hazard Control and Lead Hazard... follows: 1. Lead Based Paint Hazard Control Grant Program A total of $69,700,000 was awarded to 29 grantees for the Lead Based Paint Hazard Control Grant Program and an additional $2,388,637 was awarded to...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Showalter, Timothy N., E-mail: tns3b@virginia.edu; Hegarty, Sarah E.; Division of Biostatistics, Department of Pharmacology and Experimental Therapeutics, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania
Purpose: Although the likelihood of radiation-related adverse events influences treatment decisions regarding radiation therapy after prostatectomy for eligible patients, the data available to inform decisions are limited. This study was designed to evaluate the genitourinary, gastrointestinal, and sexual adverse events associated with postprostatectomy radiation therapy and to assess the influence of radiation timing on the risk of adverse events. Methods: The Regione Emilia-Romagna Italian Longitudinal Health Care Utilization Database was queried to identify a cohort of men who received radical prostatectomy for prostate cancer during 2003 to 2009, including patients who received postprostatectomy radiation therapy. Patients with prior radiation therapymore » were excluded. Outcome measures were genitourinary, gastrointestinal, and sexual adverse events after prostatectomy. Rates of adverse events were compared between the cohorts who did and did not receive postoperative radiation therapy. Multivariable Cox proportional hazards models were developed for each class of adverse events, including models with radiation therapy as a time-varying covariate. Results: A total of 9876 men were included in the analyses: 2176 (22%) who received radiation therapy and 7700 (78%) treated with prostatectomy alone. In multivariable Cox proportional hazards models, the additional exposure to radiation therapy after prostatectomy was associated with increased rates of gastrointestinal (rate ratio [RR] 1.81; 95% confidence interval [CI] 1.44-2.27; P<.001) and urinary nonincontinence events (RR 1.83; 95% CI 1.83-2.80; P<.001) but not urinary incontinence events or erectile dysfunction. The addition of the time from prostatectomy to radiation therapy interaction term was not significant for any of the adverse event outcomes (P>.1 for all outcomes). Conclusion: Radiation therapy after prostatectomy is associated with an increase in gastrointestinal and genitourinary adverse events. However, the timing of radiation therapy did not influence the risk of radiation therapy–associated adverse events in this cohort, which contradicts the commonly held clinical tenet that delaying radiation therapy reduces the risk of adverse events.« less
2010 Annual Health Physics Report for the HEU Transparency Program
DOE Office of Scientific and Technical Information (OSTI.GOV)
Radev, Radoslav
2011-05-16
During the 2010 calendar year, Lawrence Livermore National Laboratory (LLNL) provided health physics support for the Highly Enriched Uranium (HEU) Transparency Program for external and internal radiation protection. LLNL also provided technical expertise related to BDMS radioactive sources and Russian radiation safety regulatory compliance. For the calendar year 2010, there were 141 person-trips that required dose monitoring of the U.S. monitors. Of the 141 person-trips, 129 person-trips were Special Monitoring Visits (SMVs) and 12 person-trips were Transparency Monitoring Office (TMO) trips. In 8 of these TMO trips the TMO monitors participated also in the UEIE SMVs and in 2 TMOmore » trips the TMO monitors participated in UEIE and MPA SMVs. There were three monitoring visits (source changes) that were back-to-back SMVs with a total of 25 monitors. LLNL’s Hazard Control Department laboratories provided the dosimetry services for the HEU Transparency monitors.« less
Linus Pauling and the scientific debate over fallout hazards.
Jolly, J Christopher
2002-12-01
From 1954 to 1963, numerous scientists engaged in a public debate over the possible hazards from radioactive fallout from nuclear weapons testing. Nobel laureate Linus Pauling, a California Institute of Technology chemist, was one of the most prominent. His scientific papers relating to the fallout debate reveal many of the scientific, social and political issues involved in the controversy. Although the public controversy ended after the signing of the 1963 Limited Test Ban Treaty, many of the scientific questions about the possible hazards of low-level radiation remain under debate within the scientific community. Moreover, the fallout debate was a prototype of current controversies over environmental and public-health hazards.
Relationship between the start times of flares and CMEs to the time of potential radiation hazards
NASA Astrophysics Data System (ADS)
Kang, G.; Zheng, Y.; Kuznetsova, M. M.
2013-12-01
Solar flares, short-term outbursts of energy of the Sun, and coronal mass ejections (CME), massive bursts of solar matter, are two solar phenomena that are known to increase solar energetic particles in space. Increased solar energetic particles cause immense radiation that poses a serious threat to astronauts in space, radio communication signals, and passengers on high-latitude flights on the Earth. The relationship between the start times of flares and CMEs to the time of potential radiation hazards was investigated to determine how much warning time is available. Additionally, this project compared the difference between these relationships for four energy levels of solar energetic particles: proton flux exceeding 10 MeV, 30 MeV, 50 MeV and 100 MeV. This project gathered data of 22 recent SEP events between 2010 and 2012 and the parameters of associated CMEs and flares. Through the use of IDL (Interactive Data Language) programming, thorough analysis was conducted, including 2-sample t-tests and Kruskal-Wallis tests for 2 or more samples. The average lead time to warn humans of possible radiation hazard from the detection of a flare and a CME occurrence was found to be around 12 to 20 hours. The lead time was the greatest for the lowest energy level, though the differences in energy levels and that between the lead times for CME and flares were found to be statistically insignificant with p-values exceeding the alpha value of 0.20.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Olszewski, Adam J., E-mail: adam_olszewski@brown.edu; Desai, Amrita
2014-03-01
Purpose: To determine the factors associated with the use of radiation therapy and associated survival outcomes in early-stage marginal zone lymphoma of the mucosa-associated lymphoid tissue (MALT). Methods and Materials: We extracted data on adult patients with stage I/II MALT lymphoma diagnoses between 1998 and 2010 recorded in the Surveillance, Epidemiology, and End Results (SEER) database. We studied factors associated with radiation therapy administration in a logistic regression model and described the cumulative incidence of lymphoma-related death (LRD) according to receipt of the treatment. The association of radiation therapy with survival was explored in multivariate models with adjustment for immortalmore » time bias. Results: Of the 7774 identified patients, 36% received radiation therapy as part of the initial course of treatment. Older patients; black or Hispanic men; white, Hispanic, and black women; and socioeconomically disadvantaged and underinsured patients had a significantly lower chance of receiving radiation therapy. Radiation therapy administration was associated with a lower chance of LRD in most sites. In cutaneous, ocular, and salivary MALT lymphomas, the 5-year estimate of LRD after radiation therapy was 0%. The association of radiation therapy with overall survival in different lymphoma sites was heterogeneous, and statistically significant in cutaneous (hazard ratio 0.45, P=.009) and ocular (hazard ratio 0.47, P<.0001) locations after multivariate adjustment. Conclusions: Demographic factors are associated with the use of radiation therapy in MALT lymphoma. Clinicians should be sensitive to those disparities because the administration of radiation therapy may be associated with improved survival, particularly in cutaneous and ocular lymphomas.« less
Inactivation of ascaris lumbricoides eggs by heat, radiation, and thermoradiation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Brannen, J. P.; Garst, D. M.; Langley, S.
1975-07-01
It is desirable to eliminate the public health hazards associated with land application of municipal sewage sludge as a fertilizer or soil conditioner. This report describes experimentation to determine the effects of heat, radiation, and thermoradiation on the suppression of embryonation of Ascaris lumbricoides ova, a parasite commonly found in sewage sludge. Heat effects were observed at a minimum temperature of 51°C and radiation effects at doses in excess of 15 krads of ionizing gamma radiation. Thermoradiation at 47°C suppressed embryonation at less than half the total dose required by radiation alone.
Development of a multifunctional particle spectrometer for space radiation imaging
NASA Astrophysics Data System (ADS)
Maddox, Erik; Palacios, Alex; Lampridis, Dimitris; Kraft, Stefan; Owens, Alan; Tomuta, Dana; Ostendorf, Reint
2008-06-01
For future exploration of the solar system, the European Space Agency (ESA) is planning missions to Mercury (BepiColombo), the Sun (SolarOrbiter) and to the moons of Jupiter and Saturn. The expected intensity of radiation during such missions is hazardous for the scientific instruments and the satellite. To extend the lifetime of the satellite and its payload a multifunctional particle spectrometer (MPS) is being developed. The basic function of the MPS is to send an alarm signal to the satellite control system during periods of high radiation. In addition the MPS is a scientific instrument that will unfold the composition of the different contributing particles on-line by the dE/dx versus E method. The energy spectrum and angular distribution of the particles will be recorded as well. This article describes the main requirements and the base line design for the MPS. A readout scheme consisting of a 32 channel ASIC from IDEAS is proposed and the signal filtering algorithm will run on a digital signal processor based on FPGA technology. Results are shown from prototype calibration studies with a proton beam.
NASA Strategy to Safely Live and Work in the Space Radiation Environment
NASA Technical Reports Server (NTRS)
Cucinotta, Francis; Wu, Honglu; Corbin, Barbara; Sulzman, Frank; Kreneck, Sam
2007-01-01
This viewgraph document reviews the radiation environment that is a significant potential hazard to NASA's goals for space exploration, of living and working in space. NASA has initiated a Peer reviewed research program that is charged with arriving at an understanding of the space radiation problem. To this end NASA Space Radiation Laboratory (NSRL) was constructed to simulate the harsh cosmic and solar radiation found in space. Another piece of the work was to develop a risk modeling tool that integrates the results from research efforts into models of human risk to reduce uncertainties in predicting risk of carcinogenesis, central nervous system damage, degenerative tissue disease, and acute radiation effects acute radiation effects.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Guenoglu, K.; Akkurt, I.
Especially after development of technology, radiation started to be used in a large fields such as medicine, industry and energy. Using radiation in those fields bring hazardous effect of radiation into humancell. Thus radiation protection becomes important in physics. Although there are three ways for radiation protection, shielding of the radiation is the most commonly used method. Natural Stones such as marble is used as construction material especially in critical building and thus its radiation shielding capability should be determined.In this study, gamma ray shielding properties of some different types of marble mined in Turkey, have been measured using amore » NaI(Tl) scintillator detector. The measured results were also compared with the theoretical calculations XCOM.« less
10 CFR Appendix A to Part 20 - Assigned Protection Factors for Respirators a
Code of Federal Regulations, 2012 CFR
2012-01-01
... 10 Energy 1 2012-01-01 2012-01-01 false Assigned Protection Factors for Respirators a A Appendix A to Part 20 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Pt. 20.... External radiation hazards and other limitations to permitted exposure such as skin absorption shall be...
10 CFR Appendix A to Part 20 - Assigned Protection Factors for Respirators a
Code of Federal Regulations, 2013 CFR
2013-01-01
... 10 Energy 1 2013-01-01 2013-01-01 false Assigned Protection Factors for Respirators a A Appendix A to Part 20 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Pt. 20.... External radiation hazards and other limitations to permitted exposure such as skin absorption shall be...
10 CFR Appendix A to Part 20 - Assigned Protection Factors for Respirators a
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 1 2010-01-01 2010-01-01 false Assigned Protection Factors for Respirators a A Appendix A to Part 20 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Pt. 20.... External radiation hazards and other limitations to permitted exposure such as skin absorption shall be...
10 CFR Appendix A to Part 20 - Assigned Protection Factors for Respirators a
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 1 2011-01-01 2011-01-01 false Assigned Protection Factors for Respirators a A Appendix A to Part 20 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Pt. 20.... External radiation hazards and other limitations to permitted exposure such as skin absorption shall be...
10 CFR Appendix A to Part 20 - Assigned Protection Factors for Respirators a
Code of Federal Regulations, 2014 CFR
2014-01-01
... 10 Energy 1 2014-01-01 2014-01-01 false Assigned Protection Factors for Respirators a A Appendix A to Part 20 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Pt. 20.... External radiation hazards and other limitations to permitted exposure such as skin absorption shall be...
Base Level Management of Radio Frequency Radiation Protection Program
1989-04-01
Antennae ....... 17 5 Estimated Hazard Distance for Vertical Monopole Antennae ....... 17 6 Permissible Exposure Limits...36 H-1 Monopole Antennas .............................................. 83 H-2 Radiation Pattern of Monopole Antennas...correction factors for determining power density values in the near-field of an emitter. Power Density = (4 x P av)/(Antenna Area) (14) For dipole, monopole
NASA Astrophysics Data System (ADS)
Ponds, Charles D.; Knaur, James A.
1988-01-01
This paper presents the design and test requirements in developing an electromagnetic compatibility missile system. Environmental levels are presented for electromagnetic radiation hazards, electromagnetic radiation operational, electrostatic discharge, lightning, and electromagnetic pulse (nuclear). Testing techniques and facility capabilities are presented for research and development testing of missile systems.
Amini, Arya; Altoos, Basel; Bourlon, Maria T; Bedrick, Edward; Bhatia, Shilpa; Kessler, Elizabeth R; Flaig, Thomas W; Fisher, Christine M; Kavanagh, Brian D; Lam, Elaine T; Karam, Sana D
2015-01-01
We report the radiographic and clinical response rate of stereotactic body radiation therapy (SBRT) compared with conventional fractionated external beam radiation therapy (CF-EBRT) for renal cell carcinoma (RCC) bone lesions treated at our institution. Forty-six consecutive patients were included in the study, with 95 total lesions treated (50 SBRT, 45 CF-EBRT). We included patients who had histologic confirmation of primary RCC and radiographic evidence of metastatic bone lesions. The most common SBRT regimen used was 27 Gy in 3 fractions. Median follow-up was 10 months (range, 1-64 months). Median time to symptom control between SBRT and CF-EBRT were 2 (range, 0-6 weeks) and 4 weeks (range, 0-7 weeks), respectively. Symptom control rates with SBRT and CF-EBRT were significantly different (P = .020) with control rates at 10, 12, and 24 months of 74.9% versus 44.1%, 74.9% versus 39.9%, and 74.9% versus 35.7%, respectively. The median time to radiographic failure and unadjusted pain progression was 7 months in both groups. When controlling for gross tumor volume, dose per fraction, smoking, and the use of systemic therapy, biologically effective dose ≥80 Gy was significant for clinical response (hazard ratio [HR], 0.204; 95% confidence interval [CI], 0.043-0.963; P = .046) and radiographic (HR, 0.075; 95% CI, 0.013-0.430; P = .004). When controlling for gross tumor volume and total dose, biologically effective dose ≥80 Gy was again predictive of clinical local control (HR, 0.140; 95% CI, 0.025-0.787; P = .026). Toxicity rates were low and equivalent in both groups, with no grade 4 or 5 toxicity reported. SBRT is both safe and effective for treating RCC bone metastases, with rapid improvement in symptoms after treatment and more durable clinical and radiographic response rate. Future prospective trials are needed to further define efficacy and toxicity of treatment, especially in the setting of targeted agents. Copyright © 2015 American Society for Radiation Oncology. Published by Elsevier Inc. All rights reserved.
The heavy particle hazard, what physical data are needed?
NASA Technical Reports Server (NTRS)
Curtis, S. B.; Wilkinson, M. C.
1972-01-01
The physical data required to evaluate the radiation hazard from heavy galactic cosmic rays to astronauts on extended missions are discussed. The spectral characteristics, nuclear interaction parameters, and track structure of particles are emphasized. The data on the lower energy portion of the differential spectrum of the iron group and nuclear fragmentation in tissue and aluminum are tested, and results are shown.
Abojassim, Ali Abid; Al-Alasadi, Lubna A; Shitake, Ahmed R; Al-Tememie, Faeq A; Husain, Afnan A
2015-09-01
Biscuits are an important type of food, widely consumed by babies in Iraq and other countries. This work uses gamma spectroscopy to measure the natural radioactivity due to long-lived gamma emitters in children's biscuits; it also estimates radiation hazard indices, that is, the radium equivalent activity, the representative of gamma level index, the internal hazard index, and the annual effective dose in children. Ten samples were collected from the Iraqi market from different countries of origin. The average specific activities for (226)Ra, (232)Th, and (40)K were 9.390, 3.1213, and 214.969 Bq/kg, respectively, but the average of the radium equivalent activity and the internal hazard index were 33.101 Bq/kg and 0.107, respectively. The total average annual effective dose from consumption by adults, children, and infants is estimated to be 0.655, 1.009, and 0.875 mSv, respectively. The values found for specific activity, radiation hazard indices, and annual effective dose in all samples in this study were lower than worldwide median values for all groups; therefore, these values are found to be safe.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Schwartz, David L., E-mail: david.schwartz@utsw.edu; Harris, Jonathan; Yao, Min
2015-03-15
Purpose: To evaluate candidate fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) imaging biomarkers for head-and-neck chemoradiotherapy outcomes in the cooperative group trial setting. Methods and Materials: Radiation Therapy Oncology Group (RTOG) protocol 0522 patients consenting to a secondary FDG-PET/CT substudy were serially imaged at baseline and 8 weeks after radiation. Maximum standardized uptake value (SUVmax), SUV peak (mean SUV within a 1-cm sphere centered on SUVmax), and metabolic tumor volume (MTV) using 40% of SUVmax as threshold were obtained from primary tumor and involved nodes. Results: Of 940 patients entered onto RTOG 0522, 74 were analyzable for this substudy. Neither high baselinemore » SUVmax nor SUVpeak from primary or nodal disease were associated with poor treatment outcomes. However, primary tumor MTV above the cohort median was associated with worse local-regional control (hazard ratio 4.01, 95% confidence interval 1.28-12.52, P=.02) and progression-free survival (hazard ratio 2.34, 95% confidence interval 1.02-5.37, P=.05). Although MTV and T stage seemed to correlate (mean MTV 6.4, 13.2, and 26.8 for T2, T3, and T4 tumors, respectively), MTV remained a strong independent prognostic factor for progression-free survival in bivariate analysis that included T stage. Primary MTV remained prognostic in p16-associated oropharyngeal cancer cases, although sample size was limited. Conclusion: High baseline primary tumor MTV was associated with worse treatment outcomes in this limited patient subset of RTOG 0522. Additional confirmatory work will be required to validate primary tumor MTV as a prognostic imaging biomarker for patient stratification in future trials.« less
Moderate Image Spectrometer (MODIS) Fire Radiative Energy: Physics and Applications
NASA Technical Reports Server (NTRS)
Kaufman, Y.
2004-01-01
MODIS fire channel does not saturate in the presence of fires. The fire channel therefore is used to estimate the fire radiative energy, a measure of the rate of biomass consumption in the fire. We found correlation between the fire radiative energy, the rate of formation of burn scars and the rate of emission of aerosol from the fires. Others found correlations between the fire radiative energy and the rate of biomass consumption. This relationships can be used to estimates the emissions from the fires and to estimate the fire hazards.
Evaluation of the Potential Optical Radiation Hazards with Led Lamps Intended for Home Use.
James, Robert H; Landry, Robert J; Walker, Bennett N; Ilev, Ilko K
2017-01-01
The authors evaluated the potential for ocular damage from optical radiation emitted by Light Emitting Diode (LED) based lamps used for general illumination. Ten LED lamps were randomly selected off the shelf from a local home improvement store. The LEDs were behind diffusers in half of these lamps, while in the other half, the LEDs were clearly visible. In addition, a battery powered LED lantern having a LED source behind a diffuser was measured. The optical radiation emissions from two common incandescent lamps were also measured to compare the relative hazards of LED and incandescent lamps. All lamp samples were evaluated in accordance with procedures specified in the American National Standards Institute/Illuminating Engineering Society of North America (ANSI/IESNA) Standard RP-27.3. For comparison purposes, the lantern and 100 W incandescent lamps were also evaluated according to ANSI RP-27.1. These measurements indicate that no lamp evaluated poses any photobiological hazard, and therefore, all lamps fall in the RP-27.3 category of Exempt Group. However, when evaluated in accordance with RP-27.1, the 100 W incandescent lamp would be classified in Risk Group 1 (low risk), while the LED lantern would be classified in Risk Group 2 (moderate risk).
Miura, Shiro; Nakashima, Masahiro; Ito, Masahiro; Kondo, Hisayoshi; Meirmanov, Serik; Hayashi, Tomayoshi; Soda, Midori; Matsuo, Takeshi; Sekine, Ichiro
2008-05-15
It has been postulated that radiation induces breast cancers in atomic bomb (A-bomb) survivors. Oncogene amplification is an important mechanism during breast carcinogenesis and also serves as an indicator of genomic instability (GIN). The objective of this study was to clarify the association of oncogene amplification in breast cancer in A-bomb survivors with radiation exposure. In total, 593 breast cancers were identified in A-bomb survivors from 1968 to 1999, and the association between breast cancer incidence and A-bomb radiation exposure was evaluated. Invasive ductal cancers from 67 survivors and 30 nonsurvivors were analyzed for amplification of the HER2 and C-MYC genes by fluorescence in situ hybridization, and expression levels of hormone receptors were analyzed by immunostaining. The incidence rate increased significantly as exposure distance decreased from the hypocenter (hazard ratio per 1-km decrement, 1.47; 95% confidence interval [95% CI], 1.30-1.66). The incidence of HER2 and C-MYC amplification was increased significantly in the order of the control group, the distal group (P = .0238), and the proximal group (P = .0128). Multivariate analyses revealed that distance was a risk factor for the coamplification of C-MYC and HER2 in breast cancer in survivors (odds ratio per 1-km increment, 0.17; 95% CI, 0.01-0.63). The histologic grade of breast cancers became significantly higher in the order of the control group, the distal group, and the proximal group and was associated with oncogene amplifications. The current results suggested that A-bomb radiation may affect the development of oncogene amplification by inducing GIN and may be associated with a higher histologic grade in breast cancer among A-bomb survivors. (c) 2008 American Cancer Society.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tward, Jonathan D., E-mail: Jonathan.Tward@hci.utah.edu; Jarosek, Stephanie; Chu, Haitao
Purpose: Severe urinary adverse events (UAEs) include surgical treatment of urethral stricture, urinary incontinence, and radiation cystitis. We compared the incidence of grade 3 UAEs, according to the Common Terminology Criteria for Adverse Events, after low-dose-rate (LDR) and high-dose-rate (HDR) brachytherapy, as well as after LDR plus external beam radiation therapy (EBRT) and HDR plus EBRT. Methods and Materials: Men aged >65 years with nonmetastatic prostate cancer were identified from the Surveillance, Epidemiology, and End Results–Medicare database who were treated with LDR (n=12,801), HDR (n=685), LDR plus EBRT (n=8518), or HDR plus EBRT (n=2392). The populations were balanced by propensity weighting, andmore » the Kaplan-Meier incidence of severe UAEs was compared. Propensity-weighted Cox proportional hazards models were used to compare the adjusted hazard of UAEs. These UAEs were compared with those in a cohort of men not treated for prostate cancer. Results: Median follow-up was 4.3 years. At 8 years, the propensity-weighted cumulative UAE incidence was highest after HDR plus EBRT (26.6% [95% confidence interval, 23.8%-29.7%]) and lowest after LDR (15.7% [95% confidence interval, 14.8%-16.6%]). The absolute excess risk over nontreated controls at 8 years was 1.9%, 3.8%, 8.4%, and 12.9% for LDR, HDR, LDR plus EBRT, and HDR plus EBRT, respectively. These represent numbers needed to harm of 53, 26, 12, and 8 persons, respectively. The additional risk of development of a UAE related to treatment for LDR, LDR plus EBRT, and HDR plus EBRT was greatest within the 2 years after treatment and then continued to decline over time. Beyond 4 years, the risk of development of a new severe UAE matched the baseline risk of the control population for all treatments. Conclusions: Toxicity differences were observed between LDR and HDR, but the differences did not meet statistical significance. However, combination radiation therapy (either HDR plus EBRT or LDR plus EBRT) increases the risk of severe UAEs compared with HDR alone or LDR alone. The highest increased risk of urinary toxicity occurs within the 2 years after therapy and then declines to an approximately 1% increase in incidence per year.« less
Tward, Jonathan D; Jarosek, Stephanie; Chu, Haitao; Thorpe, Cameron; Shrieve, Dennis C; Elliott, Sean
2016-08-01
Severe urinary adverse events (UAEs) include surgical treatment of urethral stricture, urinary incontinence, and radiation cystitis. We compared the incidence of grade 3 UAEs, according to the Common Terminology Criteria for Adverse Events, after low-dose-rate (LDR) and high-dose-rate (HDR) brachytherapy, as well as after LDR plus external beam radiation therapy (EBRT) and HDR plus EBRT. Men aged >65 years with nonmetastatic prostate cancer were identified from the Surveillance, Epidemiology, and End Results-Medicare database who were treated with LDR (n=12,801), HDR (n=685), LDR plus EBRT (n=8518), or HDR plus EBRT (n=2392). The populations were balanced by propensity weighting, and the Kaplan-Meier incidence of severe UAEs was compared. Propensity-weighted Cox proportional hazards models were used to compare the adjusted hazard of UAEs. These UAEs were compared with those in a cohort of men not treated for prostate cancer. Median follow-up was 4.3 years. At 8 years, the propensity-weighted cumulative UAE incidence was highest after HDR plus EBRT (26.6% [95% confidence interval, 23.8%-29.7%]) and lowest after LDR (15.7% [95% confidence interval, 14.8%-16.6%]). The absolute excess risk over nontreated controls at 8 years was 1.9%, 3.8%, 8.4%, and 12.9% for LDR, HDR, LDR plus EBRT, and HDR plus EBRT, respectively. These represent numbers needed to harm of 53, 26, 12, and 8 persons, respectively. The additional risk of development of a UAE related to treatment for LDR, LDR plus EBRT, and HDR plus EBRT was greatest within the 2 years after treatment and then continued to decline over time. Beyond 4 years, the risk of development of a new severe UAE matched the baseline risk of the control population for all treatments. Toxicity differences were observed between LDR and HDR, but the differences did not meet statistical significance. However, combination radiation therapy (either HDR plus EBRT or LDR plus EBRT) increases the risk of severe UAEs compared with HDR alone or LDR alone. The highest increased risk of urinary toxicity occurs within the 2 years after therapy and then declines to an approximately 1% increase in incidence per year. Copyright © 2016. Published by Elsevier Inc.
Hazards, risks and safety of diagnostic ultrasound.
Duck, Francis A
2008-12-01
The safety of exposure to diagnostic ultrasound is evaluated using a structured approach to risk assessment, based on the acoustic output of present ultrasound scanners. Thermal hazard is described, the magnitude and probability of temperature rise is reviewed, and the severity of harm from any outcome is reviewed. Similar assessments are made separately for acoustic cavitation and gas-body effects, which have previously been considered together. Finally, radiation pressure is considered in a similar manner. In each case, means to minimize the risk are suggested where appropriate. The highest risks are associated with the use of gas-bubble contrast agents. It is concluded that there is a medium risk associated with trans-cranial Doppler use, and that this use of ultrasound deserves more detailed safety review. The risks associated with the current practice of obstetric ultrasound are low. Whilst the severity of radiation pressure as a hazard is low, it is always present. Little is known about any associated cell responses and so the associated risk cannot be evaluated.
Rashed-Nizam, Quazi Muhammad; Rahman, Md. Mashiur; Kamal, Masud; Chowdhury, Mantazul Islam
2015-01-01
Soil samples from the three residential hubs of Chittagong city, Bangladesh were analyzed using gamma spectrometry to estimate radiation hazard due to natural radioactive sources and anthropogenic nuclide 137Cs. The activity concentration of 226Ra was found to be in the range 11–25 Bq.kg−1, 232Th in the range 38–59 Bq.kg−1 and 40K in the range 246–414 Bq.kg−1. These results were used to calculate the radiological hazard parameters including Excess of Lifetime Cancer Risk (ELCR). The estimated outdoor gamma exposure rates were 40.6–63.8 nGy.h−1. The radiation hazard index (radium equivalent activity) ranged from 90–140 Bq.kg−1. The average value of the ELCR was found to be 0.21 × 10−3, which is lower than the world average. Sporadic fallout of 137Cs was observed with an average value of 2.0 Bq.kg−1. PMID:25237039
The medical implications of space tourism.
Tarzwell, R
2000-06-01
Commercial space travel may soon be a reality. If so, microgravity, high acceleration, and radiation exposure, all known hazards, will be accessible to the general public. Therefore, space tourism has medical implications. Even though the first flights will feature space exposure times of only a few minutes, the potential may someday exist for exposure times long enough to warrant careful consideration of the potential hazards to the space-faring public. The effects of acceleration and microgravity exposure are well known on the corps of astronauts and cosmonauts. The effects of space radiation are partially known on astronauts, but much remains to be discovered. However, there are problems using astronaut data to make inferences about the general public. Astronauts are not necessarily representative of the general public, since they are highly fit, highly screened individuals. Astronaut data can tell us very little about the potential hazards of microgravity in pediatric, obstetric and geriatric populations, all of whom are potential space tourists. Key issues in standard setting will be determining acceptable limits of pre-existing disease and inferring medical standards from mission profiles. It will not be a trivial task drafting minimal medical standards for commercial space travel. It will require the collaboration of space medicine physicians, making the best guesses possible, based on limited amounts of data, with limited applicability. A helpful departure point may be the USAF Class 3 medical standard, applicable to NASA payload specialists. It is time to begin preliminary discussions toward defining those standards. acceleration, aerospace medicine, medical standards, microgravity, radiation, space, space tourism, environmental hazards, environmental medicine.
Heavy Metal Risk Management: Case Analysis
Kim, Ji Ae; Lee, Seung Ha; Choi, Seung Hyun; Jung, Ki Kyung; Park, Mi Sun; Jeong, Ji Yoon; Hwang, Myung Sil; Yoon, Hae Jung; Choi, Dal Woong
2012-01-01
To prepare measures for practical policy utilization and the control of heavy metals, hazard control related institutions by country, present states of control by country, and present states of control by heavy metals were examined. Hazard control cases by heavy metals in various countries were compared and analyzed. In certain countries (e.g., the U.S., the U.K., and Japan), hazardous substances found in foods (e.g., arsenic, lead, cadmium, and mercury) are controlled. In addition, the Joint FAO/WHO Expert Committee on Food Additives (JECFA) recommends calculating the provisional tolerable weekly intake (PTWI) of individual heavy metals instead of the acceptable daily intake (ADI) to compare their pollution levels considering their toxicity accumulated in the human body. In Korea, exposure assessments have been conducted, and in other countries, hazardous substances are controlled by various governing bodies. As such, in Korea and other countries, diverse food heavy metal monitoring and human body exposure assessments are conducted, and reducing measures are prepared accordingly. To reduce the danger of hazardous substances, many countries provide leaflets and guidelines, develop hazardous heavy metal intake recommendations, and take necessary actions. Hazard control case analyses can assist in securing consumer safety by establishing systematic and reliable hazard control methods. PMID:24278603
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-26
... Manufacturing Practice and Hazard Analysis and Risk- Based Preventive Controls for Human Food; Extension of... Manufacturing Practice and Hazard Analysis and Risk-Based Preventive Controls for Human Food'' that appeared in... Manufacturing Practice and Hazard Analysis and Risk-Based Preventive Controls for Human Food'' with a 120-day...
Techniques and instrumentation for the measurement of transient sound energy flux
NASA Astrophysics Data System (ADS)
Watkinson, P. S.; Fahy, F. J.
1983-12-01
The evaluation of sound intensity distributions, and sound powers, of essentially continuous sources such as automotive engines, electric motors, production line machinery, furnaces, earth moving machinery and various types of process plants were studied. Although such systems are important sources of community disturbance and, to a lesser extent, of industrial health hazard, the most serious sources of hearing hazard in industry are machines operating on an impact principle, such as drop forges, hammers and punches. Controlled experiments to identify major noise source regions and mechanisms are difficult because it is normally impossible to install them in quiet, anechoic environments. The potential for sound intensity measurement to provide a means of overcoming these difficulties has given promising results, indicating the possibility of separation of directly radiated and reverberant sound fields. However, because of the complexity of transient sound fields, a fundamental investigation is necessary to establish the practicability of intensity field decomposition, which is basic to source characterization techniques.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Metzler, D.; Gibb, J.P.; Glover, W.A.
Compliance with the mandate of the Uranium Mill Tailings Radiation Control Act (UMTRCA) at Uranium Mill Tailings Remedial Action (UMTRA) Project sites requires implementation of a groundwater remedial action plan that meets the requirements of Subpart B of the US Environmental Protection Agency`s proposed groundwater protection standards (40 CFR 192). The UMTRA Groundwater Project will ensure that unacceptable current risk or potential risk to the public health, safety and the environment resulting from the groundwater contamination attributable to the UMTRA sites, is mitigated in a timely and cost-efficient manner. For each UMTRA processing site and vicinity property where contamination exists,more » a groundwater remedial action plan must be developed that identifies hazardous constituents and establishes acceptable concentration limits for the hazardous constituents as either (a) alternate concentration limits (ACL), (b) maximum concentration limits (MCLs), (c) supplemental standards, or (d) background groundwater quality levels. Project optimization is a strategy that will aggressively work within the current regulatory framework using all available options to meet regulatory requirements. This strategy is outlined within.« less
Hazard calculations of diffuse reflected laser radiation for the SELENE program
NASA Technical Reports Server (NTRS)
Miner, Gilda A.; Babb, Phillip D.
1993-01-01
The hazards from diffuse laser light reflections off water clouds, ice clouds, and fog and from possible specular reflections off ice clouds were assessed with the American National Standards (ANSI Z136.1-1986) for the free-electron-laser parameters under consideration for the Segmented Efficient Laser Emission for Non-Nuclear Electricity (SELENE) Program. Diffuse laser reflection hazards exist for water cloud surfaces less than 722 m in altitude and ice cloud surfaces less than 850 m in altitude. Specular reflections from ice crystals in cirrus clouds are not probable; however, any specular reflection is a hazard to ground observers. The hazard to the laser operators and any ground observers during heavy fog conditions is of such significant magnitude that the laser should not be operated in fog.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chen, Allen M.; Bucci, M. Kara; Weinberg, Vivian
2006-09-01
Purpose: This study sought to review a single-institution experience with the management of adenoid cystic carcinoma of the head and neck. Methods and Materials: Between 1960 and 2004, 140 patients with adenoid cystic carcinoma of the head and neck were treated with definitive surgery. Ninety patients (64%) received postoperative radiation to a median dose of 64 Gy (range, 54-71 Gy). Distribution of T stage was: 26% T1, 28% T2, 20% T3, and 26% T4. Seventy-eight patients (56%) had microscopically positive margins. Median follow-up was 66 months (range, 7-267 months). Results: The 5- and 10-year rate estimates of local control weremore » 88% and 77%, respectively. A Cox proportional hazards model identified T4 disease (p = 0.0001), perineural invasion (p = 0.008), omission of postoperative radiation (p = 0.007), and major nerve involvement (p = 0.02) as independent predictors of local recurrence. Radiation dose lower than 60 Gy (p = 0.0004), T4 disease (p 0.005), and major nerve involvement (p = 0.02) were predictors of local recurrence among those treated with surgery and postoperative radiation. The 10-year overall survival and distant metastasis-free survival were 64% and 66%, respectively. Conclusion: Combined-modality therapy with surgery followed by radiation to doses in excess of 60 Gy should be considered the standard of care for adenoid cystic carcinoma of the head and neck.« less
NASA Astrophysics Data System (ADS)
Kirillov, A. I.; Morskov, V. F.; Ustinov, N. D.
The basic criteria for dosimetric standards on photon, microwave, and ultraviolet emissions are reviewed. Attention is given to the biophysical effects of laser radiation, approaches to the evaluation of optical radiation hazard, and the effect of laser beams on the human eye. The fundamentals of the optical design of dosimeters are discussed, and an eye model is developed for a laser radiation meter. The discussion also covers the design of the electronic circuit of dosimeters and an evaluation of measurement errors.
Effects of ionizing radiation in ginkgo and guarana [rapid communication
NASA Astrophysics Data System (ADS)
Rabelo Soriani, Renata; Cristina Satomi, Lucilia; Pinto, Terezinha de Jesus A.
2005-07-01
Raw plant materials normally carry high bioburden due to their origin, offering potential hazards to consumers. The use of decontamination processes is therefore an important step towards the consumer safety and therapeutical efficiency. Several authors have reported the treatment of medicinal herbs with ionizing radiation. This work evaluated the effects of different radiation doses on the microbial burden and chemical constituents of ginkgo ( Ginkgo biloba L.) and guaraná ( Paullinia cupana H.B.K.).
NASA Astrophysics Data System (ADS)
Retsky, Michael
2008-04-01
Explosively formed projectiles (EFP) are a major problem in terrorism and asymmetrical warfare. EFPs are often triggered by ordinary infrared motion detectors. A potential weak link is that such electronics are not hardened to ionizing radiation and can latch-up or enter other inoperative states after exposure to a single short event of ionizing radiation. While these can often be repaired with a power restart, they also can produce shorts and permanent damage. A problem of course is that we do not want to add radiation exposure to the long list of war related hazards. Biological systems are highly sensitive to integrated dosage but show no particular sensitivity to short pulses. There may be a way to generate short pulsed subsoil radiation to deactivate concealed electronics without introducing radiation hazards to military personnel and civilian bystanders. Electron beams of 30 MeV that can be produced by portable linear accelerators (linacs) propagate >20 m in air and 10-12 cm in soil. X-radiation is produced by bremsstrahlung and occurs subsoil beneath the point of impact and is mostly forward directed. Linacs 1.5 m long can produce 66 MWatt pulses of subsoil x-radiation 1 microsecond or less in duration. Untested as yet, such a device could be mounted on a robotic vehicle that precedes a military convoy and deactivates any concealed electronics within 10-20 meters on either side of the road.
Applications of Accelerators and Radiation Sources in the Field of Space Research and Industry.
Campajola, Luigi; Di Capua, Francesco
2016-12-01
Beyond their important economic role in commercial communications, satellites in general are critical infrastructure because of the services they provide. In addition to satellites providing information which facilitates a better understanding of the space environment and improved performance of physics experiments, satellite observations are also used to actively monitor weather, geological processes, agricultural development and the evolution of natural and man-made hazards. Defence agencies depend on satellite services for communication in remote locations, as well as for reconnaissance and intelligence. Both commercial and government users rely on communication satellites to provide communication in the event of a disaster that damages ground-based communication systems, provide news, education and entertainment to remote areas and connect global businesses. The space radiation environment is an hazard to most satellite missions and can lead to extremely difficult operating conditions for all of the equipment travelling in space. Here, we first provide an overview of the main components of space radiation environment, followed by a description of the basic mechanism of the interaction of radiation with matter. This is followed by an introduction to the space radiation hardness assurance problem and the main effects of natural radiation to the microelectronics (total ionizing dose, displacement damage and the single-event effect and a description of how different effects occurring in the space can be tested in on-ground experiments by using particle accelerators and radiation sources. We also discuss standards and the recommended procedures to obtain reliable results.
Ghoneim, Fatma M; Arafat, Eetmad A
2016-06-01
Electromagnetic fields (EMFs) are a class of non-ionizing radiation (NIR) that is emitted from mobile phone. It may have hazardous effects on parotid glands. So, we aimed to investigate the histological and histochemical changes of the parotid glands of rats exposed to mobile phone and study the possible protective role of rosemary against its harmful effect. Forty adult male albino rats were used in this study. They were classified into 4 equal groups. Group I (control), group II (control receiving rosemary), group III (mobile phone exposed group) and group IV (mobile exposed, rosemary treated group). Parotid glands were dissected out for histological and histochemical study. Moreover, measurement of oxidative stress markers; malondialdehyde (MDA) and total antioxidant capacity (TAC) was done. The results of this study revealed that rosemary has protective effect through improving the histological and histochemical picture of the parotid gland in addition of its antioxidant effect. It could be concluded from the current study, that exposure of parotid gland of rat models to electromagnetic radiation of mobile phone resulted in structural changes at the level of light and electron microscopic examination which could be explained by oxidative stress effect of mobile phone. Rosemary could play a protective role against this harmful effect through its antioxidant activity. Copyright © 2016 Elsevier GmbH. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Savenko, I.A.; Pisarenko, N.F.; Shavrin, P.I.
1961-01-01
Analysis of data obtained by Sputnik V (August 19, 1961) at about 320 km made it possible to delineate the position of the radiation belts and to estimate the amount of radiation hazard present. Scintillation counter data show that the radiation in the belts is anisotropic and that the energy flux under a layer of matter of 2 x 10/sup -3/ g cm/sup -2/ is 10/sup 10/ ev cm/sup -2/ sec/sup -1/. The mean energy released per quantum in the scintillation counter crystal is computed at 2.0 x 10/sup 5/ ev and the intensity of electrons in the outer beltmore » at 5 x 10/sup 4/ particles cm/sup -2/ sec/sup -1/. The radiation dosage absorbed inside Sputnik V was determined by dividing the amount of energy liberated in the sodium iodide crystal of the scinitillation counter by the weight of the crystal (36.4 g) without the need of a detailed examination of the composition and spectrum of the radiation. A dosage value of 7 mrad/24 hr was obtained; in terms of the RBE (relative biological effect) of the cosmic charged particles this amounted to 5O mrem/24 hr. This dosage is considered relatively safe for astronauts during flights along trajectories similar to that of Sputnik V when the sun is quiet. Solar flares, however, could bring about an increase in radiation. Owing to latitude and longitude effects and the specifi distribution of radiation at this height, the dosage per orbit ranged from 0.35 to 0.70 mrad. (OTS)« less
Laser Hazards Bibliography, January 1991
1991-01-31
retinitis pigmentosa , Adv Exp Med Biol, 77: 233-247 (1977). 3. Agarwal, L. P., and Malik, S. R. K., Solar retinitis , Br J Ophth, 43: 366-370 (1959). 4. Al... Retinitis pigmentosa : clinical management based on current concepts, Adv Exp Med Biol, 77: 181-195 (1977). 557. Wolbarsht, M. L., Safe Ocular Levels for IR...270 C. Optical Radiation Hazards - General Reviews ............ 271 D. Retinal Burns from Lasers
NASA's Space Environments and Effects (SEE) Program
NASA Technical Reports Server (NTRS)
Kauffman, Billy; Hardage, Donna; Minor, Jody; Barth, Janet; LaBel, Ken
2003-01-01
This viewgraph presentation gives a broad overview of NASA's Space Enivronments and Effects (SEE) Program. The purpose of the program is to protect spacecraft and their systems from damage by radiation, spacecraft charging, micrometeoroids, contamination, and other hazards posed by aerospace environments. The presentation profiles SEE activities to address each of these hazards. SEE is responsible for overseeing research and product development with a variety of partners.
Radiation protection for manned space activities
NASA Technical Reports Server (NTRS)
Jordan, T. M.
1983-01-01
The Earth's natural radiation environment poses a hazard to manned space activities directly through biological effects and indirectly through effects on materials and electronics. The following standard practices are indicated that address: (1) environment models for all radiation species including uncertainties and temporal variations; (2) upper bound and nominal quality factors for biological radiation effects that include dose, dose rate, critical organ, and linear energy transfer variations; (3) particle transport and shielding methodology including system and man modeling and uncertainty analysis; (4) mission planning that includes active dosimetry, minimizes exposure during extravehicular activities, subjects every mission to a radiation review, and specifies operational procedures for forecasting, recognizing, and dealing with large solar flaes.
Measurements of energetic particle radiation in transit to Mars on the Mars Science Laboratory.
Zeitlin, C; Hassler, D M; Cucinotta, F A; Ehresmann, B; Wimmer-Schweingruber, R F; Brinza, D E; Kang, S; Weigle, G; Böttcher, S; Böhm, E; Burmeister, S; Guo, J; Köhler, J; Martin, C; Posner, A; Rafkin, S; Reitz, G
2013-05-31
The Mars Science Laboratory spacecraft, containing the Curiosity rover, was launched to Mars on 26 November 2011, and for most of the 253-day, 560-million-kilometer cruise to Mars, the Radiation Assessment Detector made detailed measurements of the energetic particle radiation environment inside the spacecraft. These data provide insights into the radiation hazards that would be associated with a human mission to Mars. We report measurements of the radiation dose, dose equivalent, and linear energy transfer spectra. The dose equivalent for even the shortest round-trip with current propulsion systems and comparable shielding is found to be 0.66 ± 0.12 sievert.
Delivery outcome among physiotherapists in Sweden: is non-ionizing radiation a fetal hazard
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kallen, B.; Malmquist, G.; Moritz, U.
1982-03-01
A cohort study was made on 2,043 infants born to 2,018 females registered as physiotherapists at the time of pregnancy during 1973 to 1978. The incidence of perinatal death, serious malformation, short gestational duration, and low birth weight was slightly below the expected with consideration given to maternal age and parity distribution. Information on occupational exposure (use of shortwave, microwave, and ultrasonic equipment, X-ray exposure, use of electrostimulator or hexachlorophene-containing soaps) was obtained in a case-control study within the cohort from mail questionnaires with a 93% response rate. The only positive finding was a higher incidence of shortwave equipment usemore » among the females with a dead or malformed infant than among controls. Various explanations for this finding are discussed.« less
NASA Technical Reports Server (NTRS)
Loomis, M. P.; Arnold, J. L.
2005-01-01
New concepts for protective shields for NASA s Crew Exploration Vehicles (CEVs) and planetary probes offer improved mission safety and affordability. Hazards include radiation from cosmic rays and solar particle events, hypervelocity impacts from orbital debris/ micrometeorites, and the extreme heating environment experienced during entry into planetary atmospheres. The traditional approach for the design of protection systems for these hazards has been to create single-function shields, i.e. ablative and blanket-based heat shields for thermal protection systems (TPS), polymer or other low-molecular-weight materials for radiation shields, and multilayer, Whipple-type shields for protection from hypervelocity impacts. This paper introduces an approach for the development of a single, multifunctional protective shield, employing nanotechnology- based materials, to serve simultaneously as a TPS, an impact shield and as the first line of defense against radiation. The approach is first to choose low molecular weight ablative TPS materials, (existing and planned for development) and add functionalized carbon nanotubes. Together they provide both thermal and radiation (TR) shielding. Next, impact protection (IP) is furnished through a tough skin, consisting of hard, ceramic outer layers (to fracture the impactor) and sublayers of tough, nanostructured fabrics to contain the debris cloud from the impactor before it can penetrate the spacecraft s interior.
Radiation safety standards: space hazards vs. terrestrial hazards.
Sinclair, W K
1983-01-01
The standards currently recommended for use in space travel were perhaps the first risk derived recommendations for dose limitations developed for quasi-occupational circumstances. They were based on data, considerations, and philosophy existing prior to 1970 and considered carcinogenesis primarily. In the intervening twelve years, not only has radiation risk information improved markedly but considerations relating to risk in general have become better known. The earlier recommendations have been examined with respect to changes in risk estimation and it is noted that the same philosophy used today, would probably lead to different dose limitations. However, other philosophies might be used; in particular a comparison of risks between terrestrial occupational radiation circumstances and also with fatal accident rates in a range of industries can be made and might be used in a modified philosophy with respect to risks from carcinogenesis. Developments have also taken place with respect to the knowledge of the biological effects of HZE particles but whether these effects are limiting as compared with radiation induced carcinogenesis is not yet clear. More studies on the effects of HZE particles, now becoming available, are needed. It is recommended that an in depth reexamination be undertaken of the biological effectiveness of space radiations and the philosophy of dose limitations in comparison with other risks.
Digital methods for reducing radiation exposure during medical fluoroscopy
NASA Astrophysics Data System (ADS)
Edmonds, Ernest W.; Rowlands, John A.; Hynes, David M.; Toth, B. D.; Porter, Anthony J.
1990-07-01
There is increased concern over radiation exposure to the general population from many sources. One of the most significant sources is that received by the patient during medical diagnostic procedures, and of these, the procedure with the greatest potential hazard is fluoroscopy. The legal limit for fluoroscopy in most jurisdictions is SR per minute skin exposure rate. Fluoroscopes are often operated in excess of this figure, and in the case of interventional procedures, fluorocopy times may exceed 20 minutes. With improvements in medical technology these procedures are being performed more often, and also are being carried out on younger age groups. Radiation exposure during fluoroscopy, both to patient and operator, is therefore becoming a matter of increasing concern to regulating authorities, and it is incumbent on us to develop digital technology to minimise the radiation hazard in these procedures. This paper explores the technical options available for radiation exposure reduction, including pulsed fluoroscopy, digital noise reduction, or simple reduction in exposure rate to the x-ray image intensifier. We also discuss educational aspects of fluoroscopy which radiologists should be aware of which can be more important than the technological solutions. A "work in progress" report gives a completely new approach to the implementation of a large number of possible digital algorithms, for the investigation of clinical efficacy.
Small unmanned aircraft system for remote contour mapping of a nuclear radiation field
NASA Astrophysics Data System (ADS)
Guss, Paul; McCall, Karen; Malchow, Russell; Fischer, Rick; Lukens, Michael; Adan, Mark; Park, Ki; Abbott, Roy; Howard, Michael; Wagner, Eric; Trainham, Clifford P.; Luke, Tanushree; Mukhopadhyay, Sanjoy; Oh, Paul; Brahmbhatt, Pareshkumar; Henderson, Eric; Han, Jinlu; Huang, Justin; Huang, Casey; Daniels, Jon
2017-09-01
For nuclear disasters involving radioactive contamination, small unmanned aircraft systems (sUASs) equipped with nuclear radiation detection and monitoring capability can be very important tools. Among the advantages of a sUAS are quick deployment, low-altitude flying that enhances sensitivity, wide area coverage, no radiation exposure health safety restriction, and the ability to access highly hazardous or radioactive areas. Additionally, the sUAS can be configured with the nuclear detecting sensor optimized to measure the radiation associated with the event. In this investigation, sUAS platforms were obtained for the installation of sensor payloads for radiation detection and electro-optical systems that were specifically developed for sUAS research, development, and operational testing. The sensor payloads were optimized for the contour mapping of a nuclear radiation field, which will result in a formula for low-cost sUAS platform operations with built-in formation flight control. Additional emphases of the investigation were to develop the relevant contouring algorithms; initiate the sUAS comprehensive testing using the Unmanned Systems, Inc. (USI) Sandstorm platforms and other acquired platforms; and both acquire and optimize the sensors for detection and localization. We demonstrated contour mapping through simulation and validated waypoint detection. We mounted a detector on a sUAS and operated it initially in the counts per second (cps) mode to perform field and flight tests to demonstrate that the equipment was functioning as designed. We performed ground truth measurements to determine the response of the detector as a function of source-to-detector distance. Operation of the radiation detector was tested using different unshielded sources.
Biochemical and histological studies on adverse effects of mobile phone radiation on rat's brain.
Hussein, Shaymaa; El-Saba, Abdel-Aleem; Galal, Mona K
2016-12-01
With the rapid development of electronic technologies, the public concern about the potential health hazards induced by radiofrequency (RF) radiation has been grown. To investigate the effect of 1800MHz RF radiation emitted from mobile phone on the rat's brain, the present study was performed. Forty male rats were randomly divided into two equal groups; control and exposed group. The later one exposed to 1800MHz emitted from mobile phone with an SAR value of 0.6W/kg for two hours/day for three months. The brain tissues were collected at the end of the experimental period and separated into hippocampus and cerebellum for subsequent biochemical, histological, immunohistochemical and electron microscopic investigations. The rats that were exposed to RF- radiation had a significant elevation in MDA content and a significant reduction in antioxidant parameters (glutathione, super oxide dismutase and glutathione peroxidase) in both regions. Degenerative changes were observed in the hippocampus pyramidal cells, dark cells and cerebellar Purkinje cells with vascular congestion. In addition a significant DNA fragmentation and over expression of cyclooxygenase-2 apoptotic gene was detected. Those results suggested that, direct chronic exposure to mobile phone caused severe biochemical and histopathological changes in the brain. Copyright © 2016 Elsevier B.V. All rights reserved.
Shielding Strategies for Human Space Exploration
NASA Technical Reports Server (NTRS)
Wilson J. W. (Editor); Miller, J. (Editor); Konradi, A. (Editor); Cucinotta, F. A. (Editor)
1997-01-01
A group of twenty-nine scientists and engineers convened a 'Workshop on Shielding Strategies for Human Space Exploration' at the Lyndon B. Johnson Space Center in Houston, Texas. The provision of shielding for a Mars mission or a Lunar base from the hazards of space radiations is a critical technology since astronaut radiation safety depends on it and shielding safety factors to control risk uncertainty appear to be great. The purpose of the workshop was to define requirements for the development and evaluation of high performance shield materials and designs and to develop ideas regarding approaches to radiation shielding. The workshop was organized to review the recent experience on shielding strategies gained in studies of the 'Space Exploration Initiative (SEI),' to review the current knowledge base for making shield assessment, to examine a basis for new shielding strategies, and to recommend a strategy for developing the required technologies for a return to the moon or for Mars exploration. The uniqueness of the current workshop arises from the expected long duration of the missions without the protective cover of the geomagnetic field in which the usually small and even neglected effects of the galactic cosmic rays (GCR) can no longer be ignored. It is the peculiarity of these radiations for which the inter-action physics and biological action are yet to be fully understood.
Development of New Laser Protective Dyes. Phase 2.
DYE LASERS, PROTECTION, LASERS, DYES , HAZARDS, SYNTHESIS, EYE SAFETY, OPTICAL MATERIALS, PLASTICS, LENSES, THERMAL STABILITY, CYANINE DYES , POLYCARBONATES, INJECTION MOLDING, NEAR INFRARED RADIATION, FLUORENES.
Robotic control and inspection verification
NASA Technical Reports Server (NTRS)
Davis, Virgil Leon
1991-01-01
Three areas of possible commercialization involving robots at the Kennedy Space Center (KSC) are discussed: a six degree-of-freedom target tracking system for remote umbilical operations; an intelligent torque sensing end effector for operating hand valves in hazardous locations; and an automatic radiator inspection device, a 13 by 65 foot robotic mechanism involving completely redundant motors, drives, and controls. Aspects concerning the first two innovations can be integrated to enable robots or teleoperators to perform tasks involving orientation and panal actuation operations that can be done with existing technology rather than waiting for telerobots to incorporate artificial intelligence (AI) to perform 'smart' autonomous operations. The third robot involves the application of complete control hardware redundancy to enable performance of work over and near expensive Space Shuttle hardware. The consumer marketplace may wish to explore commercialization of similiar component redundancy techniques for applications when a robot would not normally be used because of reliability concerns.
1974-09-15
wvironmental, levels of Table, 2o.A.. C- antenn pi tn dD. Most radz. systems use. pulse modulation as opposed to the continuous carrier, or doppler...d:io- 11 m:,.ncLlc fleld (ai’pere tu-,na/zcter), a;:,i c -t wLn -, -i n , 2 func- tion i . i’.*:av antcrian, currci.L loop ’,, or cavity PA - power...8217.,, , -... :. ; Best at a leL,_ t )4AVSEA OD 30303 FIR$T TUwV5o.4 Disivibuied BildewireCylindrical Cavity (a) Vertical or Loop Antenrn Unsah’~ Med rnb
Measurement of natural radioactivity in building materials used in Urumqi, China.
Ding, Xiang; Lu, Xinwei; Zhao, Caifeng; Yang, Guang; Li, Nan
2013-07-01
Building materials contain natural radionuclides (226)Ra, (232)Th and (40)K, which cause direct radiation exposure of the public. The concentrations of (226)Ra, (232)Th and (40)K in commonly used building materials of Urumqi, China have been analysed using gamma-ray spectrometry. The concentrations of (226)Ra, (40)K and (232)Th in the studied building materials range from 19.8 to 87.4, from 273.3 to 981.2 and from 11.6 to 47.7 Bq kg(-1), respectively. The radium equivalent activity (Raeq), gamma index (Iγ) and alpha index (Iα) were calculated to assess the radiation hazards to people living in dwellings made of the materials studied. The calculated Raeq values of all the building materials are lower than the limit of 370 Bq kg(-1) for building materials. The values of Iγ and Iα of all the building materials are less than unity. The study shows that these materials may be safely used as construction materials and do not pose significant radiation hazards.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gordon, C.J.
1991-01-01
During magnetic resonance imaging (MRI) procedures, a subject is exposed to three novel environmental stimuli which have drawn attention over the past decade as potential health hazards: (1) a relatively intense static magnetic field; (2) a time-varying magnetic field, and (3) a radiofrequency (RF) field. Thermoregulation is one of many physiological systems that can be affected by MRI, specifically by the RF radiation absorbed by the subject during MRI. While there is some sparse, albeit controversial data on the possible effects of static magnetic fields on thermoregulation, the major concern regarding potential health hazards of the MRI-induced thermal effects centersmore » on the RF radiation absorbed by a subject during a scan. The purpose of the paper is to review the studies that have impacted on understanding the thermoregulatory effects of MRI with special emphasis on the problems of selecting appropriate animal models for assessing the potential risk of RF radiation exposure during MRI.« less
Predictions for Radiation Shielding Materials
NASA Technical Reports Server (NTRS)
Kiefer, Richard L.
2002-01-01
Radiation from galactic cosmic rays (GCR) and solar particle events (SPE) is a serious hazard to humans and electronic instruments during space travel, particularly on prolonged missions outside the Earth s magnetic fields. Galactic cosmic radiation (GCR) is composed of approx. 98% nucleons and approx. 2% electrons and positrons. Although cosmic ray heavy ions are 1-2% of the fluence, these energetic heavy nuclei (HZE) contribute 50% of the long-term dose. These unusually high specific ionizations pose a significant health hazard acting as carcinogens and also causing microelectronics damage inside spacecraft and high-flying aircraft. These HZE ions are of concern for radiation protection and radiation shielding technology, because gross rearrangements and mutations and deletions in DNA are expected. Calculations have shown that HZE particles have a strong preference for interaction with light nuclei. The best shield for this radiation would be liquid hydrogen, which is totally impractical. For this reason, hydrogen-containing polymers make the most effective practical shields. Shielding is required during missions in Earth orbit and possibly for frequent flying at high altitude because of the broad GCR spectrum and during a passage into deep space and LunarMars habitation because of the protracted exposure encountered on a long space mission. An additional hazard comes from solar particle events (SPEs) which are mostly energetic protons that can produce heavy ion secondaries as well as neutrons in materials. These events occur at unpredictable times and can deliver a potentially lethal dose within several hours to an unshielded human. Radiation protection for humans requires safety in short-term missions and maintaining career exposure limits within acceptable levels on future long-term exploration missions. The selection of shield materials can alter the protection of humans by an order of magnitude. If improperly selected, shielding materials can actually increase radiation damage due to penetration properties and nuclear fragmentation. Protecting space-borne microelectronics from single event upsets (SEUs) by transmitted radiation will benefit system reliability and system design cost by using optimal shield materials. Long-term missions on the surface of the Moon or Mars will require the construction of habitats to protect humans during their stay. One approach to the construction is to make structural materials from lunar or Martian regolith using a polymeric material as a binder. The hydrogen-containing polymers are considerably more effective for radiation protection than the regolith, but the combination minimizes the amount of polymer to be transported. We have made composites of simulated lunar regolith with two different polymers, LaRC-SI, a high-performance polyimide thermoset, and polyethylene, a thermoplastic.
NASA Technical Reports Server (NTRS)
Curtis, S. B.; Wilkinson, M. C.
1971-01-01
The secondary dose contribution expected from the heavy primaries of the galactic cosmic rays was evaluated by a calculational technique developed in this study. Improvements in the solar and galactic cosmic ray environments made possible by recent experimental and theoretical work are discussed and presented. The recommendations of the National Academy of Sciences' space radiation study panel, are used in conjunction with a shielding analysis, to evaluate the radiation status of an astronaut during the triple solar particle event of 10, 14, 16 July 1959.
1981-09-01
setting and application of RFR safety standards, assessment of RFR levels in the military workplaces, RFR instrumentation and dosimetry , the medical...RADIOFREQUENCY BURN HAZARDS IN THE MF/HF BAND ................ ... 76 S. J. Rogers (U.K.) 3. RADIOFREQUENCY RADIATION INSTRUMENTATION AND DOSIMETRY ...97 B. Audone, L. Bolla, and G. Gerbi (Italy) RADIOFREQUENCY RADIATION DOSIMETRY : A REVIEW OF THEORETICAL METHODS AND EXPERIMENTAL RESULTS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Buchanan, J. R.
The risks of nuclear power and radiation are described to place them in perspective with other potential hazards faced by the public on a day-to-day basis in our complex industrial society. Twenty articles on this general topic that have appeared in Nuclear Safety are reprinted, since they collectively form a valuable reference source. Topics covered include the effects of radiation, riskbenefit concepts, radiation risks relative to other risks, nuclear plant risks relative to fossil plant risks, licensing requirements, nuclear insurance, nuclear industry safety record, and public attitudes. (auth)
Design considerations for the use of laser-plasma accelerators for advanced space radiation studies
NASA Astrophysics Data System (ADS)
Königstein, T.; Karger, O.; Pretzler, G.; Rosenzweig, J. B.; Hidding, B.; Hidding
2012-08-01
We present design considerations for the use of laser-plasma accelerators for mimicking space radiation and testing space-grade electronics. This novel application takes advantage of the inherent ability of laser-plasma accelerators to produce particle beams with exponential energy distribution, which is a characteristic shared with the hazardous relativistic electron flux present in the radiation belts of planets such as Earth, Saturn and Jupiter. Fundamental issues regarding laser-plasma interaction parameters, beam propagation, flux development, and experimental setup are discussed.
[Anthropogenic sources of radiation hazard in the near-Earth space].
Fedoseev, G A
2004-01-01
All plausible artificial radioactive sources entering the near-Earth space (NES) were systematized and consequences of various large radiation accidents and catastrophes to Earth and NES were analyzed. Aggressive "population" of near-Earth orbits by space stations with rotating crews, unmanned research platforms and observatories extends "borderlines" of the noosphere raising at the same time concerns about the noosphere radiation safety and global radioecology. Specifically, consideration is given to the facts of negative effects of space power reactor facilities on results of orbital astrophysical investigations.
Nirwane, Abhijit; Sridhar, Vinay; Majumdar, Anuradha
2016-01-01
The impact of mobile phone (MP) radiation on the brain is of specific interest to the scientific community and warrants investigations, as MP is held close to the head. Studies on humans and rodents revealed hazards MP radiation associated such as brain tumors, impairment in cognition, hearing etc. Melatonin (MT) is an important modulator of CNS functioning and is a neural antioxidant hormone. Zebrafish has emerged as a popular model organism for CNS studies. Herein, we evaluated the impact of GSM900MP (GSM900MP) radiation exposure daily for 1 hr for 14 days with the SAR of 1.34W/Kg on neurobehavioral and oxidative stress parameters in zebrafish. Our study revealed that, GSM900MP radiation exposure, significantly decreased time spent near social stimulus zone and increased total distance travelled, in social interaction test. In the novel tank dive test, the GSM900MP radiation exposure elicited anxiety as revealed by significantly increased time spent in bottom half; freezing bouts and duration and decreased distance travelled, average velocity, and number of entries to upper half of the tank. Exposed zebrafish spent less time in the novel arm of the Y-Maze, corroborating significant impairment in learning as compared to the control group. Exposure decreased superoxide dismutase (SOD), catalase (CAT) activities whereas, increased levels of reduced glutathione (GSH) and lipid peroxidation (LPO) was encountered showing compromised antioxidant defense. Treatment with MT significantly reversed the above neurobehavioral and oxidative derangements induced by GSM900MP radiation exposure. This study traced GSM900MP radiation exposure induced neurobehavioral aberrations and alterations in brain oxidative status. Furthermore, MT proved to be a promising therapeutic candidate in ameliorating such outcomes in zebrafish. PMID:27123163
Robots, systems, and methods for hazard evaluation and visualization
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nielsen, Curtis W.; Bruemmer, David J.; Walton, Miles C.
A robot includes a hazard sensor, a locomotor, and a system controller. The robot senses a hazard intensity at a location of the robot, moves to a new location in response to the hazard intensity, and autonomously repeats the sensing and moving to determine multiple hazard levels at multiple locations. The robot may also include a communicator to communicate the multiple hazard levels to a remote controller. The remote controller includes a communicator for sending user commands to the robot and receiving the hazard levels from the robot. A graphical user interface displays an environment map of the environment proximatemore » the robot and a scale for indicating a hazard intensity. A hazard indicator corresponds to a robot position in the environment map and graphically indicates the hazard intensity at the robot position relative to the scale.« less
Impact of Jovian radiation environmental hazard on spacecraft and mission development design
NASA Technical Reports Server (NTRS)
Divita, E.
1972-01-01
The environmental impact on the TOPS 12L configuration is discussed. The activities in system environmental design and testing are described, and radiation design restraints based on the upper limit model are given. Range energy cutoffs in aluminum are also presented and the effective shielding thicknesses for electrons and protons of different energies are included. Design integration problems and radiation testing aspects are considered. Data are given for selecting the parts which should be tested in a formal test program, and the piece-part radiation thresholds are tabulated for electrons and protons.
NASA Technical Reports Server (NTRS)
Tai, H.; Wilson, J. W.; Maiden, D. L.
2003-01-01
The atmospheric ionizing radiation (AIR) ER-2 preflight analysis, one of the first attempts to obtain a relatively complete measurement set of the high-altitude radiation level environment, is described in this paper. The primary thrust is to characterize the atmospheric radiation and to define dose levels at high-altitude flight. A secondary thrust is to develop and validate dosimetric techniques and monitoring devices for protecting aircrews. With a few chosen routes, we can measure the experimental results and validate the AIR model predictions. Eventually, as more measurements are made, we gain more understanding about the hazardous radiation environment and acquire more confidence in the prediction models.
Radiation Effects on Emerging Technologies: Implications of Space Weather Risk Management
NASA Technical Reports Server (NTRS)
LaBel, Kenneth A.; Barth, Janet L.
2000-01-01
As NASA and its space partners endeavor to develop a network of satellites capable of supporting humankind's needs for advanced space weather prediction and understanding, one of the key challenges is to design a space system to operate in the natural space radiation environment In this paper, we present a description of the natural space radiation environment, the effects of interest to electronic or photonic systems, and a sample of emerging technologies and their specific issues. We conclude with a discussion of operations in the space radiation hazard and considerations for risk management.
[Biosafety in laboratories concerning exposure to biological agents].
Vonesch, N; Tomao, P; Di Renzi, S; Vita, S; Signorini, S
2006-01-01
Laboratory workers are exposed to a variety of potential occupational health hazards including those deriving from infectious materials and cultures, radiations, toxic and flammable chemicals, as well as mechanical and electrical hazard. Although all of them are significant, this paper will focus on biological hazards present in clinical and research laboratories. In fact, in spite of numerous publications, guidelines and regulations, laboratory workers are still subject to infections acquired in the course of their researches. This paper describes some aspects that include good microbiological practices (GMPs), appropriate containment equipment, practices and operational procedures to minimize workers' risk of injury or illness.
Solar cosmic ray hazard to interplanetary and earth-orbital space travel
NASA Technical Reports Server (NTRS)
Yucker, W. R.
1972-01-01
A statistical treatment of the radiation hazards to astronauts due to solar cosmic ray protons is reported to determine shielding requirements for solar proton events. More recent data are incorporated into the present analysis in order to improve the accuracy of the predicted mission fluence and dose. The effects of the finite data sample are discussed. Mission fluence and dose versus shield thickness data are presented for mission lengths up to 3 years during periods of maximum and minimum solar activity; these correspond to various levels of confidence that the predicted hazard will not be exceeded.
Aggarwal, Himani; Callahan, Christopher M; Miller, Kathy D; Tu, Wanzhu; Loehrer, Patrick J
2015-10-01
To explore differences in treatment and survival outcome between poor, older black and white women with breast cancer. Retrospective cohort study. Public safety net hospital. Women aged 65 and older diagnosed with breast cancer from 1999 to 2008 (n = 1,000). Breast cancer treatments that black and white women sought were compared using the Pearson chi-square test. All-cause mortality of black and white women was compared using hazard ratios derived from a multivariate Cox proportional hazards model. There was no significant difference between older black and white women in surgical treatment, radiation therapy, chemotherapy, or hormone therapy over the study period. Race was not a significant predictor of survival in the Cox proportional hazards model that controlled for stage of cancer, age at diagnosis, dual-eligibility status, comorbid conditions, body mass index, smoking history, mammogram screening, and treatment for breast cancer. Race did not appear to affect treatment or mortality in a cohort of older women with low socioeconomic status. This may be associated with similar healthcare delivery and equivalent access to health care for the older black and white women in this study. © 2015, Copyright the Authors Journal compilation © 2015, The American Geriatrics Society.
Trading jobs for health: ionizing radiation, occupational ethics, and the welfare argument.
Shrader-Frechette, Kristin
2002-04-01
Blue-collar workers throughout the world generally face higher levels of pollution than the public and are unable to control many health risks that employers impose on them. Economists tend to justify these risky workplaces on the grounds of the compensating wage differential (CWD). The CWD, or hazard-pay premium, is the alleged increment in wages, all things being equal, that workers in hazardous environments receive. According to this theory, employees trade safety for money on the job market, even though they realize some of them will bear the health consequences of their employment in a risky occupational environment. To determine whether the CWD or hazard-pay premium succeeds in justifying alleged environmental injustices in the workplace, this essay (1) surveys the general theory behind the "compensating wage differential"; (2) presents and evaluates the "welfare argument" for the CWD; (3) offers several reasons for rejecting the CWD, as a proposed rationale for allowing apparent environmental injustice in the workplace; and (4) applies the welfare argument to an empirical case, that of US nuclear workers. The essay concludes that this argument fails to provide a justification for the apparent environmental injustice faced by the 600,000 US workers who have labored in government nuclear-weapons plants and laboratories.
Radiation Hazard from Galactic Cosmic Rays
NASA Astrophysics Data System (ADS)
Farahat, Ashraf
2006-03-01
Space radiation is a major hazard to astronauts in long-duration human space explosion. Astronauts are exposed to an enormous amount of radiation during their missions away from the Earth in outer space. Deep space is a rich environment of protons, gamma rays and cosmic rays. A healthy 40 years old man staying on Earth away from large doses of radiation stands a 20% chance of dying from cancer. If the same person travels into a 3- year Mars mission, the added risk should increase by 19%. This indicates that there is 39% chance of having cancer after he comes back to Earth. Female astronaut chances to get cancer is even almost double the above percentage. The greatest threat to astronauts en route to the red planet is galactic cosmic rays (GCR). GCRs penetrate through the skin of spaceships and people like tiny firearm bullets, breaking the strands of DNA molecules, damaging genes, and killing cells. Understanding the nature of the GCRs, their effect on biological cells, and their interactions with different shielding materials is the key point to shield against them in long space missions. In this paper we will present a model to evaluate the biological effects of GCRs and suggestion different ways to shield against them.
Challenges and Issues of Radiation Damage Tools for Space Missions
NASA Astrophysics Data System (ADS)
Tripathi, Ram; Wilson, John
2006-04-01
NASA has a new vision for space exploration in the 21st Century encompassing a broad range of human and robotic missions including missions to Moon, Mars and beyond. Exposure from the hazards of severe space radiation in deep space long duration missions is `the show stopper.' Thus, protection from the hazards of severe space radiation is of paramount importance for the new vision. Accurate risk assessments critically depend on the accuracy of the input information about the interaction of ions with materials, electronics and tissues. A huge amount of essential experimental information for all the ions in space, across the periodic table, for a wide range of energies of several (up to a Trillion) orders of magnitude are needed for the radiation protection engineering for space missions that is simply not available (due to the high costs) and probably never will be. In addition, the accuracy of the input information and database is very critical and of paramount importance for space exposure assessments particularly in view the agency's vision for deep space exploration. The vital role and importance of nuclear physics, related challenges and issues, for space missions will be discussed, and a few examples will be presented for space missions.
Natural Hazards of the Space Environment
NASA Technical Reports Server (NTRS)
Evans, Steven W.; Kross, Dennis A. (Technical Monitor)
2000-01-01
Spacecraft in Low Earth Orbit (LEO) are subject to numerous environmental hazards. Here I'll briefly discuss three environment factors that pose acute threats to the survival of spacecraft systems and crew: atmospheric drag, impacts by meteoroids and orbital debris, and ionizing radiation. Atmospheric drag continuously opposes the orbital motion of a satellite, causing the orbit to decay. This decay will lead to reentry if not countered by reboost maneuvers. Orbital debris is a by-product of man's activities in space, and consists of objects ranging in size from miniscule paint chips to spent rocket stages and dead satellites. Ionizing radiation experienced in LEO has several components: geomagnetically trapped protons and electrons (Van Allen belts); energetic solar particles; galactic cosmic rays; and albedo neutrons. These particles can have several types of prompt harmful effects on equipment and crew, from single-event upsets, latchup, and burnout of electronics, to lethal doses to crew.All three types of prompt threat show some dependence on the solar activity cycle. Atmospheric drag mitigation and large debris avoidance require propulsive maneuvers. M/OD and ionizing radiation require some form of shielding for crew and sensitive equipment. Limiting exposure time is a mitigation technique for ionizing radiation and meteor streams.
76 FR 45592 - Delegation of Authority for the Office of Healthy Homes and Lead Hazard Control
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-29
... the Office of Healthy Homes and Lead Hazard Control AGENCY: Office of the Secretary, HUD. ACTION... of 1992, the Office of Healthy Homes and Lead Hazard Control (OHHLHC) is authorized to develop, demonstrate, and promote measures to correct lead-based paint-related health and safety hazards in the home...
NASA Astrophysics Data System (ADS)
Heikal, M.; Ghoneim, M.; El Galy, M.; El Dousky, B.; Sherif, M.
2012-04-01
Sharm El Sheikh area represents one of the most touristic resort allover the world. This area is surrounded by such exposures of Precambrian granites and dike swarms as well as Miocene-Pliocene sedimentary rocks that imply more or less radionuclides U, Th, Ra and K. The radioactivity imposed within the Precambrian rocks has carefully focalized on both field and lab using up-to-date equipments and instruments. In order to evaluate the radiological hazard of the natural radioactivity, the radium equivalent activity (Raeq), gamma activity concentration index (Iγ), external hazard index (Hex) internal hazard index (Hin) and annual effective dose rate (AEDR) have been calculated and compared with the internationally approved values. The permissible values for each index revealed that all exposures of granite and mafic dikes have values below safety limits of radiation. The stream sediments within the major wadis are also safe and available for the population and agricultural purposes and/or as construction materials. On the other hand, the felsic dikes that occur far from Sharm El Sheikh town exceed the permissible radiation limits indicating their environmental hazards impacts. It was recommended to restrict land use in a buffer zone adjacent to the felsic dikes of very limited distributions. A planned major town extension of Sharm El Sheikh area has to be stopped around and within these dikes sites, but alternative future residential areas could be delineated to the northwest of the town. An intensive coordination with the Ministry of Environmental Affairs of Egypt, the town planners and other affected authorities guarantees must take into considerations the outstanding integration of the recommendations of our study into future town and regional land use planning.
Evaluation of radiation hazard potential of TENORM waste from oil and natural gas production.
Hilal, M A; Attallah, M F; Mohamed, Gehan Y; Fayez-Hassan, M
2014-10-01
In this study, a potential radiation hazard from TENORM sludge wastes generated during exploration and extraction processes of oil and gas was evaluated. The activity concentration of natural radionuclides (238)U, (226)Ra and (232)Th were determined in TENORM sludge waste. It was found that sludge waste from oil and gas industry is one of the major sources of (226)Ra in the environment. Therefore, some preliminary chemical treatment of sludge waste using Triton X-100 was also investigated to reduce the radioactivity content as well as the risk of radiation hazard from TENORM wastes. The activity concentrations of (226)Ra and (228)Ra in petroleum sludge materials before and after chemical treatment were measured using gamma-ray spectrometry. The average values of the activity concentrations of (226)Ra and (228)Ra measured in the original samples were found as 8908 Bq kg(-1) and 933 Bq kg(-1), respectively. After chemical treatment of TENORM samples, the average values of the activity concentrations of (226)Ra and (228)Ra measured in the samples were found as 7835 Bq kg(-1) and 574 Bq kg(-1), respectively. Activity concentration index, internal index, absorbed gamma dose rate and the corresponding effective dose rate were estimated for untreated and treated samples. Copyright © 2014 Elsevier Ltd. All rights reserved.
Allodji, Rodrigue S; Diallo, Ibrahima; El-Fayech, Chiraz; Kahlouche, Amar; Dumas, Agnès; Schwartz, Boris; Oberlin, Odile; Benadjaoud, Mohamed Amine; Labbé, Martine; Jackson, Angela; Bullet, Julien; Rubino, Carole; Haddy, Nadia; De Vathaire, Florent
2016-04-01
Few studies have been published on the association of the radiation dose received to the eyes during radiotherapy (RT) for childhood cancer and the risk for later cataract. To investigate the risk for cataract after treatment of nonretinoblastoma solid cancer in childhood. The study used data from the Euro2K cohort that includes 4389 5-year survivors of solid tumors treated from January 1, 1945, to December 31, 1985; of these, 3172 patients were treated in France. A self-reported questionnaire was sent to French survivors from September 1, 2005, to December 31, 2012, when follow-up was considered completed for this study. However, 619 patients died before the beginning of the study and 128 patients treated for a retinoblastoma or who underwent enucleation were excluded. Likewise, 429 patients with unknown addresses or who did not return the consent form and 163 nonresponders did not participate. The remaining 1833 patients who completed the questionnaire underwent analysis for this study from June 1, 2014, to December 7, 2015. Radiation doses in both eyes for individuals were estimated for all patients who had received RT. The role of the radiation dose in cataract risk was investigated using the Cox proportional hazard regression model and the excess relative or the absolute risk model. The role of ctytotoxic chemotherapy was also investigated. The 1833 patients (961 men [52.4%]; 872 women [47.6%]; mean [SD] age, 37.0 [8.5]) who returned the questionnaire were included in the analysis. After a mean follow-up of 32 years, 33 patients with unilateral or bilateral cataract were identified, for a total of 47 cataract events. The 47 events were validated by medical record review and by contacting the patients and the corresponding medical physician or ophthalmologist to obtain copies of diagnostic examinations or surgical reports. Overall, in a multivariable Cox proportional hazard regression analysis, patients who received RT had a 4.4-fold (95% CI, 1.5- to 13.0-fold) increased risk for cataract compared with patients who did not receive RT. Exposure to radiation doses of at least 10 Gy to the eyes increased the hazard ratio 39-fold (95% CI, 12.0- to 127.9-fold), relative to no radiation exposure. Although based on few patients, a strong increase in cataract risk (hazard ratio, 26.3; 95% CI, 7.1-96.6) was observed in patients treated with melphalan hydrochloride. This study can inform guideline-based recommendations for long-term follow-up for cataract.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sole, Claudio V., E-mail: csole@iram.cl; School of Medicine, Complutense University, Madrid; Calvo, Felipe A.
Purpose: To assess long-term outcomes and toxicity of intraoperative electron-beam radiation therapy (IOERT) in the management of pediatric patients with Ewing sarcomas (EWS) and rhabdomyosarcomas (RMS). Methods and Materials: Seventy-one sarcoma (EWS n=37, 52%; RMS n=34, 48%) patients underwent IOERT for primary (n=46, 65%) or locally recurrent sarcomas (n=25, 35%) from May 1983 to November 2012. Local control (LC), overall survival (OS), and disease-free survival were estimated using Kaplan-Meier methods. For survival outcomes, potential associations were assessed in univariate and multivariate analyses using the Cox proportional hazards model. Results: After a median follow-up of 72 months (range, 4-310 months), 10-year LC, disease-freemore » survival, and OS was 74%, 57%, and 68%, respectively. In multivariate analysis after adjustment for other covariates, disease status (P=.04 and P=.05) and R1 margin status (P<.01 and P=.04) remained significantly associated with LC and OS. Nine patients (13%) reported severe chronic toxicity events (all grade 3). Conclusions: A multimodal IOERT-containing approach is a well-tolerated component of treatment for pediatric EWS and RMS patients, allowing reduction or substitution of external beam radiation exposure while maintaining high local control rates.« less
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-13
... and Hazardous Substances Pollution Contingency Plan National Priorities List AGENCY: Environmental... protection, Air pollution control, Chemicals, Hazardous Waste, Hazardous substances, Intergovernmental relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control, Water...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-18
... protection, Air pollution control, Chemicals, Hazardous Waste, Hazardous substances, Intergovernmental relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control, Water... and Hazardous Substances Pollution Contingency Plan; National Priorities List AGENCY: Environmental...
Enhanced control & sensing for the REMOTEC ANDROS Mk VI robot. Final report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Spelt, P.F.; Harvey, H.W.
1997-08-01
This Cooperative Research and Development Agreement (CRADA) between Lockheed Marietta Energy Systems, Inc., and REMOTEC, Inc., explored methods of providing operator feedback for various work actions of the ANDROS Mk VI teleoperated robot. In a hazardous environment, an extremely heavy workload seriously degrades the productivity of teleoperated robot operators. This CRADA involved the addition of computer power to the robot along with a variety of sensors and encoders to provide information about the robot`s performance in and relationship to its environment. Software was developed to integrate the sensor and encoder information and provide control input to the robot. ANDROS Mkmore » VI robots are presently used by numerous electric utilities to perform tasks in reactors where substantial exposure to radiation exists, as well as in a variety of other hazardous environments. Further, this platform has potential for use in a number of environmental restoration tasks, such as site survey and detection of hazardous waste materials. The addition of sensors and encoders serves to make the robot easier to manage and permits tasks to be done more safely and inexpensively (due to time saved in the completion of complex remote tasks). Prior research on the automation of mobile platforms with manipulators at Oak Ridge National Laboratory`s Center for Engineering Systems Advanced Research (CESAR, B&R code KC0401030) Laboratory, a BES-supported facility, indicated that this type of enhancement is effective. This CRADA provided such enhancements to a successful working teleoperated robot for the first time. Performance of this CRADA used the CESAR laboratory facilities and expertise developed under BES funding.« less
21 CFR 120.8 - Hazard Analysis and Critical Control Point (HACCP) plan.
Code of Federal Regulations, 2010 CFR
2010-04-01
...: (i) Critical control points designed to control food hazards that are reasonably likely to occur and could be introduced inside the processing plant environment; and (ii) Critical control points designed... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Hazard Analysis and Critical Control Point (HACCP...
21 CFR 120.8 - Hazard Analysis and Critical Control Point (HACCP) plan.
Code of Federal Regulations, 2012 CFR
2012-04-01
...: (i) Critical control points designed to control food hazards that are reasonably likely to occur and could be introduced inside the processing plant environment; and (ii) Critical control points designed... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Hazard Analysis and Critical Control Point (HACCP...
21 CFR 120.8 - Hazard Analysis and Critical Control Point (HACCP) plan.
Code of Federal Regulations, 2013 CFR
2013-04-01
...: (i) Critical control points designed to control food hazards that are reasonably likely to occur and could be introduced inside the processing plant environment; and (ii) Critical control points designed... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Hazard Analysis and Critical Control Point (HACCP...
21 CFR 120.8 - Hazard Analysis and Critical Control Point (HACCP) plan.
Code of Federal Regulations, 2014 CFR
2014-04-01
...: (i) Critical control points designed to control food hazards that are reasonably likely to occur and could be introduced inside the processing plant environment; and (ii) Critical control points designed... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Hazard Analysis and Critical Control Point (HACCP...
21 CFR 120.8 - Hazard Analysis and Critical Control Point (HACCP) plan.
Code of Federal Regulations, 2011 CFR
2011-04-01
...: (i) Critical control points designed to control food hazards that are reasonably likely to occur and could be introduced inside the processing plant environment; and (ii) Critical control points designed... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Hazard Analysis and Critical Control Point (HACCP...
Hall, Amy L; Davies, Hugh W; Demers, Paul A; Nicol, Anne-Marie; Peters, Cheryl E
2013-11-01
Although veterinary workers may encounter various occupational health hazards, a national characterization of exposures is lacking in Canada. This study used secondary data sources to identify veterinary exposure prevalence for ionizing radiation and antineoplastic agents, as part of a national surveillance project. For ionizing radiation, data from the Radiation Protection Bureau of Health Canada were used to identify veterinarians and veterinary technicians monitored in 2006. This was combined with Census statistics to estimate a prevalence range and dose levels. For antineoplastic agents, exposure prevalence was estimated using statistics on employment by practice type and antineoplastic agent usage rates, obtained from veterinary licensing bodies and peer-reviewed literature. In 2006, 7,013 (37% of all) Canadian veterinary workers were monitored for ionizing radiation exposure. An estimated 3.3% to 8.2% of all veterinarians and 2.4% to 7.2% of veterinary technicians were exposed to an annual ionizing radiation dose above 0.1 mSv, representing a total of between 536 and 1,450 workers. All monitored doses were below regulatory limits. For antineoplastic agents, exposure was predicted in up to 5,300 (23%) of all veterinary workers, with an estimated prevalence range of 22% to 24% of veterinarians and 20% to 21% of veterinary technicians. This is the first national-level assessment of exposure to ionizing radiation and antineoplastic agents in Canadian veterinary settings. These hazards may pose considerable health risks. Exposures appeared to be low, however our estimates should be validated with comprehensive exposure monitoring and examination of determinants across practice areas, occupations, and tasks.
24 CFR 35.1330 - Interim controls.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 24 Housing and Urban Development 1 2012-04-01 2012-04-01 false Interim controls. 35.1330 Section... Lead-Paint Hazard Evaluation and Hazard Reduction Activities § 35.1330 Interim controls. Interim controls of lead-based paint hazards identified in a risk assessment shall be conducted in accordance with...
Shafirkin, A V; Kolomenskiĭ, A V
2008-01-01
According to recent workups, the Mars mission spacecraft will be designed with an electrical jet microthrusters rather than a power reactor facility. The article contains analysis of the main sources of radiation hazard during the exploration mission using this cost-efficient, ecological, easy-to-operate propulsion powered by solar arrays. In addition, the authors make predictions of the generalized doses of ionizing radiation for mission durations of 730 and 900 days behind various shielding thicknesses, and on the Martian surface. Calculation algorithms are described and radiation risks are estimated for the crew life span and possible life time reduction in consequence of participation in the mission.
A New Perspective on Trapped Radiation Belts in Planetary Atmospheres
NASA Technical Reports Server (NTRS)
Diaz, A.; Lodhi, M. A. K.; Wilson, T. L.
2005-01-01
The charged particle fluxes trapped in the magnetic dipole fields of certain planets in our Solar System are interesting signatures of planetary properties in space physics. They also represent a source of potentially hazardous radiation to spacecraft during planetary and interplanetary exploration. The Earth s trapped radiation belts have been studied for years and the physical mechanisms by which primary radiation from the Sun and Galaxy is captured is well understood. The higher-energy particles collide with molecules in the planetary atmosphere and initiate large cascades of secondary radiation which itself becomes trapped by the magnetic dipole field of the planet. Some of it is even backscattered as albedo neutrons.
Asteroid Apophis: Evaluating the impact hazards of such bodies
NASA Astrophysics Data System (ADS)
Shuvalov, V. V.; Svettsov, V. V.; Artem'eva, N. A.; Trubetskaya, I. A.; Popova, O. P.; Glazachev, D. O.
2017-01-01
Soon after the discovery of asteroid 99942 Apophis, it was classified as a potentially hazardous object with a high probability of an impact on the Earth in 2029. Although subsequent observations have substantially reduced the probability of a collision, it has not been ruled out; moreover, similar-sized asteroids in orbits intersecting the Earth's orbit may well be discovered in the near future. We conduct a numerical simulation of an atmospheric passage and an impact on the Earth's surface of a stony cosmic body with a diameter of 300 m and kinetic energy of about 1000 Mt, which roughly corresponds to the parameters of the asteroid Apophis, at atmospheric entry angles of 90° (vertical stroke), 45°, and 30°. The simulation is performed by solving three-dimensional equations of hydrodynamics and radiative transfer equations in the approximations of radiative heat conduction and volume emission. The following hazards are considered: an air shock wave, ejecta from the crater, thermal radiation, and ionospheric disturbances. Our calculations of the overpressure and wind speed on the Earth's surface show that the zone of destruction of the weakest structures can be as large as 700-1000 km in diameter; a decrease in the flight path angle to the surface leads to a marked increase in the area affected by the shock wave. The ionospheric disturbances are global in nature and continue for hours: at distances of several thousand kilometers at altitudes of more than 100 km, air density disturbances are tens of percent and the vertical and horizontal velocity components reach hundreds of meters per second. The impact of radiation on objects on the Earth's surface is estimated by solving the equation of radiative transfer along rays passing through a luminous area. In clear weather, the size of the zone where thermal heating may ignite wood can be as large as 200 km, and the zone of individual fire outbreaks associated with the ignition of flammable materials can be twice as large. In the 100-km central area, which is characterized by very strong thermal damage, there is ignition of structures, roofs, clothes, etc. The human hazardous area increases with the decrease in the trajectory angle, and people may experience thermal effects at distances of up to 250-400 km from the crater.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-13
... and Hazardous Substances Pollution Contingency Plan National Priorities List AGENCY: Environmental... pollution control, Chemicals, Hazardous Waste, Hazardous substances, Intergovernmental relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control, Water supply. Authority: 33 U...
Interval From Imaging to Treatment Delivery in the Radiation Surgery Age: How Long Is Too Long?
DOE Office of Scientific and Technical Information (OSTI.GOV)
Seymour, Zachary A., E-mail: seymourz@radonc.ucsf.edu; Fogh, Shannon E.; Westcott, Sarah K.
Purpose: The purpose of this study was to evaluate workflow and patient outcomes related to frameless stereotactic radiation surgery (SRS) for brain metastases. Methods and Materials: We reviewed all treatment demographics, clinical outcomes, and workflow timing, including time from magnetic resonance imaging (MRI), computed tomography (CT) simulation, insurance authorization, and consultation to the start of SRS for brain metastases. Results: A total of 82 patients with 151 brain metastases treated with SRS were evaluated. The median times from consultation, insurance authorization, CT simulation, and MRI for treatment planning were 15, 7, 6, and 11 days to SRS. Local freedom from progressionmore » (LFFP) was lower in metastases with MRI ≥14 days before treatment (P=.0003, log rank). The 6- and 12-month LFFP rate were 95% and 75% for metastasis with interval of <14 days from MRI to treatment compared to 56% and 34% for metastases with MRI ≥14 days before treatment. On multivariate analysis, LFFP remained significantly lower for lesions with MRI ≥14 days at SRS (P=.002, Cox proportional hazards; hazard ratio: 3.4, 95% confidence interval: 1.6-7.3). Conclusions: Delay from MRI to SRS treatment delivery for brain metastases appears to reduce local control. Future studies should monitor the timing from imaging acquisition to treatment delivery. Our experience suggests that the time from MRI to treatment should be <14 days.« less
Radiation shielding properties of barite coated fabric by computer programme
DOE Office of Scientific and Technical Information (OSTI.GOV)
Akarslan, F.; Molla, T.; Üncü, I. S.
2015-03-30
With the development of technology radiation started to be used in variety of different fields. As the radiation is hazardous for human health, it is important to keep radiation dose as low as possible. This is done mainly using shielding materials. Barite is one of the important materials in this purpose. As the barite is not used directly it can be used in some other materials such as fabric. For this purposes barite has been coated on fabric in order to improve radiation shielding properties of fabric. Determination of radiation shielding properties of coated fabric has been done by usingmore » computer program written C# language. With this program the images obtained from digital Rontgen films is used to determine radiation shielding properties in terms of image processing numerical values. Those values define radiation shielding and in this way the coated barite effect on radiation shielding properties of fabric has been obtained.« less
Overview of the Martian radiation environment experiment
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zeitlin, C.; Cleghorn, T.F.; Cucinotta, F.A.
Space radiation presents a hazard to astronauts, particularly those journeying outside the protective influence of the geomagnetosphere. Crews on future missions to Mars will be exposed to the harsh radiation environment of deep space during the transit between Earth and Mars. Once on Mars, they will encounter radiation that is only slightly reduced, compared to free space, by the thin Martian atmosphere. NASA is obliged to minimize, where possible, the radiation exposures received by astronauts. Thus, as a precursor to eventual human exploration, it is necessary to measure the Martian radiation environment in detail. The MARIE experiment, aboard the 2001more » Mars Odyssey spacecraft, is returning the first data that bear directly on this problem. Here we provide an overview of the experiment, including introductory material on space radiation and radiation dosimetry, a description of the detector, model predictions of the radiation environment at Mars, and preliminary dose-rate data obtained at Mars.« less
Radiation Protection in Canada
Williams, N.
1965-01-01
The main emphasis of a provincial radiation protection program is on ionizing radiation produced by machines, although assistance is given to the Federal Radiation Protection Division in its program relating to radioactive substances. The basis for the Saskatchewan program of radiation protection is the Radiological Health Act 1961. An important provision of the Act is annual registration of radiation equipment. The design of the registration form encourages a “do-it-yourself” radiation and electrical safety inspection. Installations are inspected every two years by a radiation health officer. Two hundred and twenty-one deficiencies were found during inspection of 224 items of radiation equipment, the commonest being failure to use personal film badges. Insufficient filtration of the beam, inadequate limitation of the beam, and unnecessary exposure of operators were other common faults. Physicians have a responsibility to weigh the potential advantages against the hazards when requesting radiographic or fluoroscopic procedures. PMID:14282164
Handbook on Bird Management and Control.
1980-03-01
strike hazard ...................... 70 FIGURE 10. Sample application of sharp projections ........ 80 FIGURE 11. Plans for a low profile pigeon trap...particularly with Domestic Pigeons , Starlings, and House Sparrows, can reduce most of the hazards mentioned in this chapter. 4.2. HEALTH HAZARDS 4.2.1...damage, pest bird control, hazardous bird control, bird biology t behavior, altering the concept, altering the situation, exclusion, repulsion, removal
Compliance Software for Radioactive Air Emissions
Atmospheric dispersion and transport models that are used to assess radiation dose and risk and to demonstrate compliance with certain radionuclide National Emission Standards for Hazardous Air Pollutants (NESHAPs) regulations.
Evaluation of experimental methods for assessing safety for ultrasound radiation force elastography.
Skurczynski, M J; Duck, F A; Shipley, J A; Bamber, J C; Melodelima, D
2009-08-01
Standard test tools have been evaluated for the assessment of safety associated with a prototype transducer intended for a novel radiation force elastographic imaging system. In particular, safety has been evaluated by direct measurement of temperature rise, using a standard thermal test object, and detection of inertial cavitation from acoustic emission. These direct measurements have been compared with values of the thermal index and mechanical index, calculated from acoustic measurements in water using standard formulae. It is concluded that measurements using a thermal test object can be an effective alternative to the calculation of thermal index for evaluating thermal hazard. Measurement of the threshold for cavitation was subject to considerable variability, and it is concluded that the mechanical index still remains the preferred standard means for assessing cavitation hazard.
Mine, Mariko; Kondo, Hisayoshi; Matsuda, Naoki; Shibata, Yoshisada; Takamura, Noboru
2018-01-01
Abstract The health effects of radiation exposure from the atomic bomb fallout remain unclear. The objective of the present study is to elucidate the association between low-dose radiation exposure from the atomic bomb fallout and cancer mortality among Nagasaki atomic bomb survivors. Of 77 884 members in the Nagasaki University Atomic Bomb Survivors Cohort, 610 residents in the terrain-shielded area with fallout were selected for this analysis; 1443 residents in the terrain-shielded area without fallout were selected as a control group; and 3194 residents in the direct exposure area were also selected for study. Fifty-two deaths due to cancer in the terrain-shielded fallout area were observed during the follow-up period from 1 January 1970 to 31 December 2012. The hazard ratio for cancer mortality in the terrain-shielded fallout area was 0.90 (95% confidence interval: 0.65–1.24). No increase in the risk of cancer mortality was observed, probably because the dose of the radiation exposure was low for residents in the terrain-shielded fallout areas of the Nagasaki atomic bomb, and also because the number of study subjects was small. PMID:29036510
Thyroid Hormone Indices in Computer Workers with Emphasis on the Role of Zinc Supplementation.
Amin, Ahmed Ibrahim; Hegazy, Noha Mohamed; Ibrahim, Khadiga Salah; Mahdy-Abdallah, Heba; Hammouda, Hamdy A A; Shaban, Eman Essam
2016-06-15
This study aimed to investigate the effects of computer monitor-emitted radiation on thyroid hormones and the possible protective role of zinc supplementation. The study included three groups. The first group (group B) consisted of 42 computer workers. This group was given Zinc supplementation in the form of one tablet daily for eight weeks. The second group (group A) comprised the same 42 computer workers after zinc supplementation. A group of 63 subjects whose job does not entail computer use was recruited as a control Group (Group C). All participants filled a questionnaire including detailed medical and occupational histories. They were subjected to full clinical examination. Thyroid stimulating hormone (TSH), free triiodothyronine (FT3), free thyroxine (FT4) and zinc levels were measured in all participants. TSH, FT3, FT4 and zinc concentrations were decreased significantly in group B relative to group C. In group A, all tested parameters were improved when compared with group B. The obtained results revealed that radiation emitted from computers led to changes in TSH and thyroid hormones (FT3 and FT4) in the workers. Improvement after supplementation suggests that zinc can ameliorate hazards of such radiation on thyroid hormone indices.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-25
... establishment's process control plans, that is, its Hazard Analysis and Critical Control Point plans. DATES... control plans, i.e., its Hazard Analysis and Critical Control Point (HACCP) plans; and (3) make the recall... systematic prevention of biological, chemical, and physical hazards. HACCP plans are establishment-developed...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-24
... Availability for HUD's Fiscal Year (FY) 2010 Lead-Based Paint Hazard Control Grant Program and Lead Hazard Reduction Demonstration Grant Program; Technical Correction AGENCY: Office of Healthy Homes and Lead Hazard...://www.Grants.gov its Notice of Funding Availability (NOFA) for HUD's FY2010 Lead-Based Paint Hazard...
Laser safety research and modeling for high-energy laser systems
NASA Astrophysics Data System (ADS)
Smith, Peter A.; Montes de Oca, Cecilia I.; Kennedy, Paul K.; Keppler, Kenneth S.
2002-06-01
The Department of Defense has an increasing number of high-energy laser weapons programs with the potential to mature in the not too distant future. However, as laser systems with increasingly higher energies are developed, the difficulty of the laser safety problem increases proportionally, and presents unique safety challenges. The hazard distance for the direct beam can be in the order of thousands of miles, and radiation reflected from the target may also be hazardous over long distances. This paper details the Air Force Research Laboratory/Optical Radiation Branch (AFRL/HEDO) High-Energy Laser (HEL) safety program, which has been developed to support DOD HEL programs by providing critical capability and knowledge with respect to laser safety. The overall aim of the program is to develop and demonstrate technologies that permit safe testing, deployment and use of high-energy laser weapons. The program spans the range of applicable technologies, including evaluation of the biological effects of high-energy laser systems, development and validation of laser hazard assessment tools, and development of appropriate eye protection for those at risk.
Natural and anthropogenic radioactivity in the environment of Kopaonik mountain, Serbia.
Mitrović, Branislava; Ajtić, Jelena; Lazić, Marko; Andrić, Velibor; Krstić, Nikola; Vranješ, Borjana; Vićentijević, Mihajlo
2016-08-01
To evaluate the state of the environment in Kopaonik, a mountain in Serbia, the activity concentrations of (4) K, (226)Ra, (232)Th and (137)Cs in five different types of environmental samples are determined by gamma ray spectrometry, and radiological hazard due to terrestrial radionuclides is calculated. The mean activity concentrations of natural radionuclides in the soil are higher than the global average. However, with an exception of two sampling locations, the external radiation hazard index is below one, implying an insignificant radiation hazard. Apart from (40)K, content of the natural radionuclides is predominantly below minimum detectable activities in grass and cow milk, but not in mosses. Although (137)Cs is present in the soil, grass, mosses and herbal plants, its specific activity in cow milk is below minimum detectable activity. Amongst the investigated herbal plants, Vaccinium myrtillus L. shows accumulating properties, as a high content of (137)Cs is detected therein. Therefore, moderation is advised in consuming Vaccinium myrtillus L. tea. Copyright © 2016 Elsevier Ltd. All rights reserved.
Radiological Environmental Protection for LCLS-II High Power Operation
NASA Astrophysics Data System (ADS)
Liu, James; Blaha, Jan; Cimeno, Maranda; Mao, Stan; Nicolas, Ludovic; Rokni, Sayed; Santana, Mario; Tran, Henry
2017-09-01
The LCLS-II superconducting electron accelerator at SLAC plans to operate at up to 4 GeV and 240 kW average power, which would create higher radiological impacts particularly near the beam loss points such as beam dumps and halo collimators. The main hazards to the public and environment include direct or skyshine radiation, effluent of radioactive air such as 13N, 15O and 41Ar, and activation of groundwater creating tritium. These hazards were evaluated using analytic methods and FLUKA Monte Carlo code. The controls (mainly extensive bulk shielding and local shielding around high loss points) and monitoring (neutron/photon detectors with detection capabilities below natural background at site boundary, site-wide radioactive air monitors, and groundwater wells) were designed to meet the U.S. DOE and EPA, as well as SLAC requirements. The radiological design and controls for the LCW systems [including concrete housing shielding for 15O and 11C circulating in LCW, 7Be and erosion/corrosion products (22Na, 54Mn, 60Co, 65Zn, etc.) captured in resin and filters, leak detection and containment of LCW with 3H and its waste water discharge; explosion from H2 build-up in surge tank and release of radionuclides] associated with the high power beam dumps are also presented.
Arnone, Mario; Koppisch, Dorothea; Smola, Thomas; Gabriel, Stefan; Verbist, Koen; Visser, Remco
2015-10-01
Many control banding tools use hazard banding in risk assessments for the occupational handling of hazardous substances. The outcome of these assessments can be combined with advice for the required risk management measures (RMMs). The Globally Harmonised System of Classification and Labelling of Chemicals (GHS) has resulted in a change in the hazard communication elements, i.e. Hazard (H) statements instead of Risk-phrases. Hazard banding schemes that depend on the old form of safety information have to be adapted to the new rules. The purpose of this publication is to outline the rationales for the assignment of hazard bands to H statements under the GHS. Based on this, this publication proposes a hazard banding scheme that uses the information from the safety data sheets as the basis for assignment. The assignment of hazard bands tiered according to the severity of the underlying hazards supports the important principle of substitution. Additionally, the set of assignment rules permits an exposure-route-specific assignment of hazard bands, which is necessary for the proposed route-specific RMMs. Ideally, all control banding tools should apply the same assignment rules. This GHS-compliant hazard banding scheme can hopefully help to establish a unified hazard banding strategy in the various control banding tools. Copyright © 2015 Elsevier Inc. All rights reserved.
Bioeffects of microwave--a brief review.
Banik, S; Bandyopadhyay, S; Ganguly, S
2003-04-01
Since the 18th century scientists have been intrigued by the interaction of electromagnetic fields (EMFs) and various life processes. Attention has been focussed on EMFs in different frequency ranges, of which microwave frequency range forms an important part. Microwaves are part of the electromagnetic spectrum and are considered to be that radiation ranging in frequency from 300 million cycles per second (300 MHz) to 300 billion cycles per second (300 GHz), which correspond to a wavelength range of 1 m down to 1 mm. This nonionising electromagnetic radiation is absorbed at molecular level and manifests as changes in vibrational energy of the molecules or heat (Microwaves irradiating the community, Hidden hazards, Bantan Books publisher, Australia, 1991). Identifying and evaluating the biological effects of microwaves have been complex and controversial. Because of the paucity of information on the mechanism of interaction between microwave and biological systems, there has been a persistent view in physical and engineering sciences, that microwave fields are incapable of inducing bioeffects other than by heating (Health Physics 61 (1991) 3). Of late, the nonthermal effects of microwaves on tissue responses are being documented (Physiol. Rev. 61 (1981) 435; Annals of New York Acad. Sci. 247 (1975) 232; J. Microwave Power 14 (1979) 351; Bioelectromagnetics 7 (1986a) 45; Bioelectromagnetics 7 (1986b) 315; Biologic Effects and Health Hazards of Microwave Radiation, Warsaw, Polish Medical Publication (1974) 289; Biologic Effects and Health hazards of the microwave Radiation, Warsaw, Polish Medical Publication (1974) 22; Multidisciplinory perspectives in event-related brain potential research, Washington DC, US Environmental Protection Agency, (1978) 444). The present article is an attempt to familiarise the reader with pertinent information regarding the effects, mainly athermal, of microwave irradiation on biologic systems, especially microorganisms.
Space environment effects on polymers in low earth orbit
NASA Astrophysics Data System (ADS)
Grossman, E.; Gouzman, I.
2003-08-01
Polymers are widely used in space vehicles and systems as structural materials, thermal blankets, thermal control coatings, conformal coatings, adhesives, lubricants, etc. The low earth orbit (LEO) space environment includes hazards such as atomic oxygen, UV radiation, ionizing radiation (electrons, protons), high vacuum, plasma, micrometeoroids and debris, as well as severe temperature cycles. Exposure of polymers and composites to the space environment may result in different detrimental effects via modification of their chemical, electrical, thermal, optical and mechanical properties as well as surface erosion. The high vacuum induces material outgassing (e.g. low-molecular weight residues, plasticizers and additives) and consequent contamination of nearby surfaces. The present work reviews the LEO space environment constituents and their interactions with polymers. Examples of degradation of materials exposed in ground simulation facilities are presented. The issues discussed include the erosion mechanisms of polymers, formation of contaminants and their interaction with the space environment, and protection of materials from the harsh space environment.
Ropkins, K; Beck, A J
2002-08-01
Hazard analysis by critical control points (HACCP) is a systematic approach to the identification, assessment and control of hazards. Effective HACCP requires the consideration of all hazards, i.e., chemical, microbiological and physical. However, to-date most 'in-place' HACCP procedures have tended to focus on the control of microbiological and physical food hazards. In general, the chemical component of HACCP procedures is either ignored or limited to applied chemicals, e.g., food additives and pesticides. In this paper we discuss the application of HACCP to a broader range of chemical hazards, using organic chemical contaminants as examples, and the problems that are likely to arise in the food manufacturing sector. Chemical HACCP procedures are likely to result in many of the advantages previously identified for microbiological HACCP procedures: more effective, efficient and economical than conventional end-point-testing methods. However, the high costs of analytical monitoring of chemical contaminants and a limited understanding of formulation and process optimisation as means of controlling chemical contamination of foods are likely to prevent chemical HACCP becoming as effective as microbiological HACCP.
Civil Defense Home Shelters: a Viable Defense Strategy for the 1990s
1990-09-01
NUDET, ground-transmitted shock often arrives first. The exact circumstances depend 16 upon a complex mixture of seismic velocities of the soil and...settle out. This late-arriving fallout represents a very minor hazard to human health, because the radiation dose rate from fallout decays quickly...Barrier Shielding and Geometry Shielding (5:49) 34 Home Fallout Shelters A shelter should provide a place of safety from natural or man-made hazards
Bowel injury associated with pelvic radiotherapy
NASA Astrophysics Data System (ADS)
François, Agnès; Milliat, Fabien; Vozenin-Brotons, Marie-Catherine
2005-02-01
Radiation therapists have to deal with the difficulty to give an efficient radiation dose to the tumor without generating unacceptable normal tissue injury. Acute reactions are experienced in most of the patients and are characterized by diarrhea resulting from intestinal mucosal injury. In some cases, intestinal wall fibrosis may develop, with hazard of occlusion syndrome. The only therapeutic recourse consists of surgical resection of the injured bowel.
Iraq liquid radioactive waste tanks maintenance and monitoring program plan.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dennis, Matthew L.; Cochran, John Russell; Sol Shamsaldin, Emad
2011-10-01
The purpose of this report is to develop a project management plan for maintaining and monitoring liquid radioactive waste tanks at Iraq's Al-Tuwaitha Nuclear Research Center. Based on information from several sources, the Al-Tuwaitha site has approximately 30 waste tanks that contain varying amounts of liquid or sludge radioactive waste. All of the tanks have been non-operational for over 20 years and most have limited characterization. The program plan embodied in this document provides guidance on conducting radiological surveys, posting radiation control areas and controlling access, performing tank hazard assessments to remove debris and gain access, and conducting routine tankmore » inspections. This program plan provides general advice on how to sample and characterize tank contents, and how to prioritize tanks for soil sampling and borehole monitoring.« less
Management of Naturally Occurring Radioactive Materials (NORM) in Canada
DOE Office of Scientific and Technical Information (OSTI.GOV)
Baweja, Anar S.; Tracy, Bliss L.
2008-08-07
In Canada, nuclear and radiological regulatory responsibilities are shared between the provinces/territories and the federal government. The Canadian Nuclear Safety Commission (CNSC) regulates nuclear fuel cycle materials and man-made radionuclides under the Nuclear Safety and Control Act (2000). The provinces and territories regulate NORM arising from industrial activities, not involving the nuclear fuel cycle materials. Present guideline--Canadian Guidelines for the Management of Naturally Occurring Radioactive Materials (NORM)--was published in 2000 in order to bring uniformity to the management of NORM-related procedures to provide adequate radiation protection for workers and the general public. The basic premise of these guidelines is thatmore » the NORM-related activities should not be posing any greater hazard than those activities regulated under the Nuclear Safety and Control Act; these concepts are described in this paper.« less
An evaluation of treatment strategies for head and neck cancer in an African American population.
Ignacio, D N; Griffin, J J; Daniel, M G; Serlemitsos-Day, M T; Lombardo, F A; Alleyne, T A
2013-07-01
This study evaluated treatment strategies for head and neck cancers in a predominantly African American population. Data were collected utilizing medical records and the tumour registry at the Howard University Hospital. Kaplan-Meier method was used for survival analysis and Cox proportional hazards regression analysis predicted the hazard of death. Analysis revealed that the main treatment strategy was radiation combined with platinum for all stages except stage I. Cetuximab was employed in only 1% of cases. Kaplan-Meier analysis revealed stage II patients had poorer outcome than stage IV while Cox proportional hazard regression analysis (p = 0.4662) showed that stage I had a significantly lower hazard of death than stage IV (HR = 0.314; p = 0.0272). Contributory factors included tobacco and alcohol but body mass index (BMI) was inversely related to hazard of death. There was no difference in survival using any treatment modality for African Americans.
Mahdi, H; Moulton, L; Nutter, B; Cherian, S; Rose, P
2016-12-01
To investigate the impact of pelvic radiation on survival in patients with uterine clear cell carcinoma (UCC) who received adjuvant chemotherapy. Patients with stage I-IV UCC who had undergone surgery and chemotherapy were identified from the Surveillance, Epidemiology, and End Results (SEER) programm 2000-2009. Patients were divided into those who received only chemotherapy and those who received both chemotherapy and radiation therapy. Kaplan-Meier curves and Cox regression models were used for analysis. Of the 317 patients included, 195 (62%) were in the chemotherapy only group and 122 (38%) were in the chemotherapy and radiation therapy group. Pelvic radiation was associated with significant improvement in overall survival (median 88 versus 25 months, 5 year survival: 58% versus 33%, P<0.001) in the chemotherapy and radiation therapy group compared with the chemotherapy only group for the entire cohort. On subset analysis, chemotherapy and radiation therapy was associated with improved overall survival in late stage disease (III-IV) (5 year 54% versus 22%, P<0.001) compared with the chemotherapy only group, whereas in stage I-II UCC, there was no difference in overall survival between the chemotherapy and radiotherapy group and the chemotherapy only group (5 year 65% versus 67%, P=0.69). In multivariable analysis, pelvic radiation was associated with improved survival in patients with late stage disease (hazard ratio 0.57, 95% confidence interval 0.35-0.94, P=0.03) but not for early stage disease (hazard ratio 0.81, 95% confidence interval 0.33-2.0, P=0.65). Other significant predictors were advanced stage, positive cytology and extensive lymphadenectomy. Radiation was associated with significant improvement in survival in advanced stage UCC, but not in early stage UCC. These data support the beneficial role of radiation therapy in UCC, especially in patients with advanced stage disease. Copyright © 2016 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.
21 CFR 123.6 - Hazard analysis and Hazard Analysis Critical Control Point (HACCP) plan.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Hazard analysis and Hazard Analysis Critical Control Point (HACCP) plan. 123.6 Section 123.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF... processor shall have and implement a written HACCP plan whenever a hazard analysis reveals one or more food...
21 CFR 123.6 - Hazard analysis and Hazard Analysis Critical Control Point (HACCP) plan.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Hazard analysis and Hazard Analysis Critical Control Point (HACCP) plan. 123.6 Section 123.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF... processor shall have and implement a written HACCP plan whenever a hazard analysis reveals one or more food...
Persistent distress after psychological exposure to the Nagasaki atomic bomb explosion.
Kim, Yoshiharu; Tsutsumi, Atsuro; Izutsu, Takashi; Kawamura, Noriyuki; Miyazaki, Takao; Kikkawa, Takehiko
2011-11-01
Although there is speculation that individuals living in the vicinity of nuclear disasters have persistent mental health deterioration due to psychological stress, few attempts have been made to examine this issue. To determine whether having been in the vicinity of the Nagasaki atomic bomb explosion in the absence of substantial exposure to radiation affected the mental health of local inhabitants more than half a century later. Participants were randomly recruited from individuals who lived in the vicinity of the atomic bomb explosion in uncontaminated suburbs of Nagasaki. This sample (n = 347) was stratified by gender, age, perception of the explosion and current district of residence. Controls (n = 288) were recruited from among individuals who had moved into the area from outside Nagasaki 5-15 years after the bombing, matched for gender, age and district of residence. The primary outcome measure was the proportion of those at high risk of mental disorder based on the 28-item version of the General Health Questionnaire, with a cut-off point of 5/6. Other parameters related to individual perception of the explosion, health status, life events and habits were also assessed. Having been in the vicinity of the explosion was the most significant factor (OR = 5.26, 95% CI 2.56-11.11) contributing to poorer mental health; erroneous knowledge of radiological hazard showed a mild association. In the sample group, anxiety after learning of the potential radiological hazard was significantly correlated with poor mental health (P<0.05), whereas anxiety about the explosion, or the degree of perception of it, was not; 74.5% of the sample group believed erroneously that the flash of the explosion was synonymous with radiation. Having been in the vicinity of the atomic bomb explosion without radiological exposure continued to be associated with poorer mental health more than half a century after the event. Fear on learning about the potential radiological hazard and lack of knowledge about radiological risk are responsible for this association.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-19
... Manufacturing Practice and Hazard Analysis and Risk- Based Preventive Controls for Human Food; Extension of... Analysis and Risk-Based Preventive Controls for Human Food.'' FOR FURTHER INFORMATION CONTACT: Domini Bean... Practice and Hazard Analysis and Risk-Based Preventive Controls for Human Food'' with a 120-day comment...
The Revised Space Environment Models in CREME-MC: A Replacement for CREME96
NASA Technical Reports Server (NTRS)
Adams, James H., Jr.; Barghouty, Abdulnasser F.; Mendenhall, Marcus H.; Reed, Robert A.; Sierawski, Brian; Watts, John W.; Weller, Robert A.
2010-01-01
The CREME96 model has been available on the WWW for more than 10 years now. While principally for the estimation of radiation effects on spacecraft electronics, it contains space radiation environment models that have been used for instrument design calculations, estimation of instrumental background, estimation of radiation hazards and many other purposes. Because of the evolution of electronic part design we have found it necessary to revise CREME96, creating CREME-MC. As part of this revision, we are revising and extending the environmental models in CREME96. This talk will describe the revised radiation environment models that are being made available in CREME-MC
Dermatologic radiotherapy and thyroid cancer. Dose measurements and risk quantification.
Goldschmidt, H; Gorson, R O; Lassen, M
1983-05-01
Thyroid doses for various dermatologic radiation techniques were measured with thermoluminescent dosimeters and ionization rate meters in an Alderson-Rando anthropomorphic phantom. The effects of changes in radiation quality and of the use or nonuse of treatment cones and thyroid shields were evaluated in detail. The results indicate that the potential risk of radiogenic thyroid cancer is very small when proper radiation protection measures are used. The probability of radiogenic thyroid cancer developing and the potential mortality risk were assessed quantitatively for each measurement. The quantification of radiation risks allows comparisons with risks of other therapeutic modalities and the common hazards of daily life.
Exposure safety standards for nonionizing radiation (NIR) from collision-avoidance radar
NASA Astrophysics Data System (ADS)
Palmer-Fortune, Joyce; Brecher, Aviva; Spencer, Paul; Huguenin, Richard; Woods, Ken
1997-02-01
On-vehicle technology for collision avoidance using millimeter wave radar is currently under development and is expected to be in vehicles in coming years. Recently approved radar bands for collision avoidance applications include 47.5 - 47.8 GHz and 76 - 77 GHz. Widespread use of active radiation sources in the public domain would contribute to raised levels of human exposure to high frequency electromagnetic radiation, with potential for adverse health effects. In order to design collision avoidance systems that will pose an acceptably low radiation hazard, it is necessary to determine what levels of electromagnetic radiation at millimeter wave frequencies will be acceptable in the environment. This paper will summarize recent research on NIR (non-ionizing radiation) exposure safety standards for high frequency electromagnetic radiation. We have investigated both governmental and non- governmental professional organizations worldwide.
NASA Technical Reports Server (NTRS)
2012-01-01
One of the characteristics of an effective safety program is the recognition and control of hazards before mishaps or failures occur. Conducting potentially hazardous tests necessitates a thorough hazard analysis in order to protect our personnel from injury and our equipment from damage. The purpose of this hazard analysis is to define and address the potential hazards and controls associated with the Z1 Suit Port Test in Chamber B located in building 32, and to provide the applicable team of personnel with the documented results. It is imperative that each member of the team be familiar with the hazards and controls associated with his/her particular tasks, assignments, and activities while interfacing with facility test systems, equipment, and hardware. The goal of this hazard analysis is to identify all hazards that have the potential to harm personnel and/or damage facility equipment, flight hardware, property, or harm the environment. This analysis may also assess the significance and risk, when applicable, of lost test objectives when substantial monetary value is involved. The hazards, causes, controls, verifications, and risk assessment codes have been documented on the hazard analysis work sheets in appendix A of this document. The preparation and development of this report is in accordance with JPR 1700.1, JSC Safety and Health Handbook.
Henderson, R.P.
1957-09-17
An instrument carried unobtrusively about the person such as in a finger ring to indicate when that person has been exposed to an unusual radiation hazard is described. A metallized quartz fiber is electrically charged to indicate a full scale reading on an etched glass background. The quartz fiber and the scale may be viewed through a magnifying lens for ease of reading. Incident radiation will ionize gaseous particles in the sealed structure thereby allowing the charge to leak off the quartz fiber with its resulting movement across the scale proportionally indicating the radiation exposure.
Radiation Analysis for the Human Lunar Return Mission
NASA Technical Reports Server (NTRS)
Wilson, J. W.; Simonsen, L. C.; Shinn, J. L.; Kim, M.; Dubey, R. R.; Jordan, W.
1997-01-01
An analysis of the radiation hazards that are anticipated on an early Human Lunar Return (HLR) mission in support of NASA deep space exploration activities is presented. The HLR mission study emphasized a low cost lunar return to expand human capabilities in exploration, to answer fundamental science questions, and to seek opportunities for commercial development. As such, the radiation issues are cost related because the parasitic shield mass is expensive due to high launch costs. The present analysis examines the shield requirements and their impact on shield design.
Estimating Risk of Hematopoietic Acute Radiation Syndrome in Children.
Adams, Tim G; Sumner, Louise E; Casagrande, Rocco
2017-12-01
Following a radiological terrorist attack or radiation accident, the general public may be exposed to radiation. Historically, modeling efforts have focused on radiation effects on a "reference man"-a 70-kg, 180-cm-tall, 20- to 30-y-old male-which does not adequately reflect radiation hazard to special populations, particularly children. This work examines the radiosensitivity of children with respect to reference man to develop a set of parameters for modeling hematopoetic acute radiation syndrome in children. This analysis was performed using animal studies and the results verified using data from medical studies. Overall, the hematopoietic system in children is much more radiosensitive than that in adults, with the LD50 for children being 56% to 91% of the LD50 of adults, depending on age.
NASA Astrophysics Data System (ADS)
Schwadron, Nathan A.; Cooper, John F.; Desai, Mihir; Downs, Cooper; Gorby, Matt; Jordan, Andrew P.; Joyce, Colin J.; Kozarev, Kamen; Linker, Jon A.; Mikíc, Zoran; Riley, Pete; Spence, Harlan E.; Török, Tibor; Townsend, Lawrence W.; Wilson, Jody K.; Zeitlin, Cary
2017-11-01
Particle radiation has significant effects for astronauts, satellites and planetary bodies throughout the Solar System. Acute space radiation hazards pose risks to human and robotic exploration. This radiation also naturally weathers the exposed surface regolith of the Moon, the two moons of Mars, and other airless bodies, and contributes to chemical evolution of planetary atmospheres at Earth, Mars, Venus, Titan, and Pluto. We provide a select review of recent areas of research covering the origin of SEPs from coronal mass ejections low in the corona, propagation of events through the solar system during the anomalously weak solar cycle 24 and important examples of radiation interactions for Earth, other planets and airless bodies such as the Moon.
[RADIATION SAFETY DURING REMEDIATION OF THE "SEVRAO" FACILITIES].
Shandala, N K; Kiselev, S M; Titov, A V; Simakov, A V; Seregin, V A; Kryuchkov, V P; Bogdanova, L S; Grachev, M I
2015-01-01
Within a framework of national program on elimination of nuclear legacy, State Corporation "Rosatom" is working on rehabilitation at the temporary waste storage facility at Andreeva Bay (Northwest Center for radioactive waste "SEVRAO"--the branch of "RosRAO"), located in the North-West of Russia. In the article there is presented an analysis of the current state of supervision for radiation safety of personnel and population in the context of readiness of the regulator to the implementation of an effective oversight of radiation safety in the process of radiation-hazardous work. Presented in the article results of radiation-hygienic monitoring are an informative indicator of the effectiveness of realized rehabilitation measures and characterize the radiation environment in the surveillance zone as a normal, without the tendency to its deterioration.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Brink, Carsten, E-mail: carsten.brink@rsyd.dk; Laboratory of Radiation Physics, Odense University Hospital; Bernchou, Uffe
2014-07-15
Purpose: Large interindividual variations in volume regression of non-small cell lung cancer (NSCLC) are observable on standard cone beam computed tomography (CBCT) during fractionated radiation therapy. Here, a method for automated assessment of tumor volume regression is presented and its potential use in response adapted personalized radiation therapy is evaluated empirically. Methods and Materials: Automated deformable registration with calculation of the Jacobian determinant was applied to serial CBCT scans in a series of 99 patients with NSCLC. Tumor volume at the end of treatment was estimated on the basis of the first one third and two thirds of the scans.more » The concordance between estimated and actual relative volume at the end of radiation therapy was quantified by Pearson's correlation coefficient. On the basis of the estimated relative volume, the patients were stratified into 2 groups having volume regressions below or above the population median value. Kaplan-Meier plots of locoregional disease-free rate and overall survival in the 2 groups were used to evaluate the predictive value of tumor regression during treatment. Cox proportional hazards model was used to adjust for other clinical characteristics. Results: Automatic measurement of the tumor regression from standard CBCT images was feasible. Pearson's correlation coefficient between manual and automatic measurement was 0.86 in a sample of 9 patients. Most patients experienced tumor volume regression, and this could be quantified early into the treatment course. Interestingly, patients with pronounced volume regression had worse locoregional tumor control and overall survival. This was significant on patient with non-adenocarcinoma histology. Conclusions: Evaluation of routinely acquired CBCT images during radiation therapy provides biological information on the specific tumor. This could potentially form the basis for personalized response adaptive therapy.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bishop, Andrew J.; Zagars, Gunar K.; Torres, Keila E.
2015-09-01
Purpose: The purpose of this study was to investigate local control, survival outcomes, and complication rates of patients treated with aggressive surgery and radiation therapy (RT) for retroperitoneal sarcomas (RPS). Methods and Materials: We reviewed the medical records of 121 consecutive patients treated for RPS with surgery and RT between 1965 and 2012. The most common histology was liposarcoma (n=42; 35%). The median follow-up was 100 months (range: 20-467 months). Eighty-six patients (71%) were treated for initial presentation of RPS, and 35 patients (29%) presented with and were treated for RPS recurrence. RT was preoperative in 88 patients (73%; median dose: 50.4 Gy)more » and postoperative in 33 patients (27%; median dose: 55 Gy). Results: Five-year local control and overall survival rates were 56% and 57%, respectively. Two factors were associated with higher risk of any intra-abdominal recurrence at 5 years: positive or uncertain margins (58% vs 30% for negative margins, P<.001; hazard ratio [HR]: 2.7; 95% confidence interval [CI]: 1.6-4.8) and disease recurrence after previous resection (76% vs 31% for de novo RPS, P<.001; HR: 4.4; 95% CI: 2.5-7.5). The 10-year complication rate was 5%, and RT-related complications were associated with postoperative RT (P<.001) and RT dose of ≥60 Gy (P<.001). Conclusions: Intra-abdominal RPS recurrence continues to be a significant challenge despite the use of aggressive surgery and radiation therapy. Given the complications associated with postoperative radiation therapy, we recommend that preoperative radiation therapy is the preferred strategy when combined modality therapy is recommended.« less
Hazard Analysis for Building 34 Vacuum Glove Box Assembly
NASA Technical Reports Server (NTRS)
Meginnis, Ian
2014-01-01
One of the characteristics of an effective safety program is the recognition and control of hazards before mishaps or failures occur. Conducting potentially hazardous tests necessitates a thorough hazard analysis in order to prevent injury to personnel, and to prevent damage to facilities and equipment. The primary purpose of this hazard analysis is to define and address the potential hazards and controls associated with the Building 34 Vacuum Glove Box Assembly, and to provide the applicable team of personnel with the documented results. It is imperative that each member of the team be familiar with the hazards and controls associated with his/her particular tasks, assignments and activities while interfacing with facility test systems, equipment and hardware. In fulfillment of the stated purposes, the goal of this hazard analysis is to identify all hazards that have the potential to harm personnel, damage the facility or its test systems or equipment, test articles, Government or personal property, or the environment. This analysis may also assess the significance and risk, when applicable, of lost test objectives when substantial monetary value is involved. The hazards, causes, controls, verifications, and risk assessment codes have been documented on the hazard analysis work sheets in Appendix A of this document. The preparation and development of this report is in accordance with JPR 1700.1, "JSC Safety and Health Handbook" and JSC 17773 Rev D "Instructions for Preparation of Hazard Analysis for JSC Ground Operations".
AAAS: Politics. . . and Science
ERIC Educational Resources Information Center
Science News, 1978
1978-01-01
Reviews topics discussed during the American Association for the Advancement of Science (AAAS) meeting held in Washington, D.C. Topics included: the equal rights amendment, laetrile, nuclear radiation hazards, sociobiology, and various science topics. (SL)
Building Protection Against External Ionizing Fallout Radiation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dillon, Michael B.; Homann, Steven G.
A nuclear explosion has the potential to injure or kill tens to hundreds of thousands of people through exposure to fallout (external gamma) radiation. Existing buildings can protect their occupants (reducing external radiation exposures) by placing material and distance between fallout particles and indoor individuals. This protection is not well captured in current fallout risk assessment models and so the US Department of Defense is implementing the Regional Shelter Analysis methodology to improve the ability of the Hazard Prediction and Assessment Capability (HPAC) model to account for building protection. This report supports the HPAC improvement effort by identifying a setmore » of building attributes (next page) that, when collectively specified, are sufficient to calculate reasonably accurate, i.e., within a factor of 2, fallout shelter quality estimates for many individual buildings. The set of building attributes were determined by first identifying the key physics controlling building protection from fallout radiation and then assessing which building attributes are relevant to the identified physics. This approach was evaluated by developing a screening model (PFscreen) based on the identified physics and comparing the screening model results against the set of existing independent experimental, theoretical, and modeled building protection estimates. In the interests of transparency, we have developed a benchmark dataset containing (a) most of the relevant primary experimental data published by prior generations of fallout protection scientists as well as (b) the screening model results.« less
Chen, Allen M; Lau, Valerie H; Farwell, D Gregory; Luu, Quang; Donald, Paul J
2013-12-01
To determine clinical and pathological correlates of outcome among patients treated by surgery and postoperative radiation therapy for mucoepidermoid carcinoma of the parotid gland. Retrospective review. The medical records of 61 patients treated by surgery and postoperative radiation therapy for localized mucoepidermoid carcinoma of the parotid gland were retrospectively reviewed in an attempt to identify clinicopathologic correlates of overall survival. Secondary endpoints included local-regional control, distant metastasis-free survival, and complications. The 3- and 5-year estimates of overall survival were 85% and 79%, respectively. Multivariate analysis identified high tumor grade (hazard ratio [HR] = 7.92) and T4 disease (HR = 3.35) as independent predictors of decreased survival, with the former also predicting for distant metastasis and the latter predicting for local-regional recurrence. The 5-year estimate of overall survival was 83% for patients with non-high-grade tumors, compared to 52% for those with high-grade histology (P = 0.001). Late complications included trismus (2 patients), osteoradionecrosis (1 patient), and hearing loss (1 patient). Patients with high-grade tumors and T4 disease are at increased risk for treatment failure after surgery and postoperative radiation therapy for mucoepidermoid carcinoma of the parotid gland. Investigative strategies to improve outcome should be considered for these particular patients in the future. Copyright © 2013 The American Laryngological, Rhinological and Otological Society, Inc.
NASA/ASEE Summer Faculty Fellowship Program. 1991 Research Reports
NASA Technical Reports Server (NTRS)
Hosler, E. Ramon (Editor); Beymer, Mark A. (Editor); Armstrong, Dennis W. (Editor)
1991-01-01
Reports from the NASA/ASEE Summer Faculty Fellowship Program are presented. The editors are responsible for selecting appropriately qualified faculty to address some of the many problems of current interest to NASA Kennedy. Some representative titles are as follows: Development of an Accelerated Test Method for the Determination of Susceptibility to Atmospheric Corrosion; Hazardous Gas Leak Analysis in the Space Shuttle; Modeling and Control of the Automated Radiator Inspection Device; Study of the Finite Element Software Packages at KSC; Multispectral Image Processing for Plants; Algorithms for Contours Depicting Static Electric Fields during Adverse Weather Conditions; Transient Study of a Cryogenic Hydrogen Filling System; and Precision Cleaning Verification of Nonvolatile Residues by using Water, Ultrasonics, and Turbidity Analyses.
Late cataractogenesis caused by particulate radiations and photons in long-lived mammalian species
NASA Technical Reports Server (NTRS)
Lett, J. T.; Lee, A. C.; Cox, A. B.; Wood, D. H.
1989-01-01
Radiation cataractogenesis induced by small acute doses of particulate radiations and photons in the New Zealand white rabbit (Oryctolagus cuniculus), the beagle dog (Canis familiaris) and the rhesus monkey (Macaca mulatta) is discussed in the context of the use of animal models to assess the radiation hazards faced by humans during lengthy sojourns in deep space. Attention is paid to (1) the importance of lifespan studies with long-lived species - the above animals have median lifespans in captivity of 5-7, 13-14 and 25 years, respectively; and (2) the magnitudes of possible dose thresholds for cataractogenesis from sparsely ionizing radiations and the modifications of those thresholds by the late degenerative phase of the phenomenon.
Tuorkey, Muobarak J
2015-09-01
Although decades have elapsed, researchers still debate the benefits and hazards of solar ultraviolet radiation (UVR) exposure. On the one hand, humans derive most of their serum 25-hydroxycholecalciferol [25(OH)D3], which has potent anticancer activity, from solar UVB radiation. On the other hand, people are more aware of the risk of cancer incidence associated with harmful levels of solar UVR from daily sunlight exposure. Epidemiological data strongly implicate UV radiation exposure as a major cause of melanoma and other cancers, as UVR promotes mutations in oncogenes and tumor-suppressor genes. This review highlights the impact of the different mutagenic effects of solar UVR, along with the cellular and carcinogenic challenges with respect to sun exposure.
Radiological implications of granite of northern Pakistan.
Asghar, M; Tufail, M; Sabiha-Javied; Abid, A; Waqas, M
2008-09-01
Granite is an igneous rock that contains natural radioactivity of primordial radionuclides. In Pakistan, granite is distributed in a vast area called the Ambela Granitic Complex (AGC) in North West Frontier Province (NWFP). Granite is a hard rock that exists in different colours and is used to decorate floors, kitchen counter tops, etc. The use of granite in a building as a decor material is a potential source of radiation dose; therefore, natural radioactivity has been measured in 20 granite samples of the AGC with an HPGe (high purity germanium) based gamma ray spectrometer. The average specific activities and their range (given in parentheses) for primordial radionuclides (40)K, (226)Ra and (232)Th were 1218 (899-1927), 659 (46-6120) and 598 (92-3214) Bq kg(-1), respectively. The measured activity concentrations were used for the assessment of hazard indices and radiation dose which were evaluated based on the permissible limits defined for these parameters. The measured specific activities and the derived quantities, hazard indices and radiation dose, have been compared with those given in the literature for these parameters.
Biological Applications and Effects of Optical Masers
1988-02-19
LANDOLT RING SYSTEM 8-10 8. EARLY STUDIES ON SOLAR RADIATION AS A RETINAL HAZARD 10-15 9. RETINAL LIGHT TOXICITY AS A FUNCTION OF WAVE’.ENGTH 15-16 10...providing a simulated solor spectrum and 10 nm bandwidths throughout the near ultraviolet, visible and near infrared spectrum. This early ocular...do not present an ocular hazard at the levels used by the MILES prototype system or in fiber optic communication systems . By 1966 enough burn
Gould, Elise
2009-01-01
Background This study is a cost–benefit analysis that quantifies the social and economic benefits to household lead paint hazard control compared with the investments needed to minimize exposure to these hazards. Objectives This research updates estimates of elevated blood lead levels among a cohort of children ≤ 6 years of age and compiles recent research to determine a range of the costs of lead paint hazard control ($1–$11 billion) and the benefits of reduction attributed to each cohort for health care ($11–$53 billion), lifetime earnings ($165–$233 billion), tax revenue ($25–$35 billion), special education ($30–$146 million), attention deficit–hyperactivity disorder ($267 million), and the direct costs of crime ($1.7 billion). Results Each dollar invested in lead paint hazard control results in a return of $17–$221 or a net savings of $181–269 billion. Conclusions There are substantial returns to investing in lead hazard control, particularly targeted at early intervention in communities most likely at risk. Given the high societal costs of inaction, lead hazard control appears to be well worth the price. PMID:19654928
NASA Astrophysics Data System (ADS)
Walter, Juergen; Brodesser, Alexander; Hustedt, Michael; Bluemel, Sven; Jaeschke, Peter; Kaierle, Stefan
Cutting and ablation using short-pulsed laser radiation are promising technologies to produce or repair CFRP components with outstanding mechanical properties e.g. for automotive and aircraft industry. Using sophisticated laser processing strategies and avoiding excessive heating of the workpiece, a high processing quality can be achieved. However, the interaction of laser radiation and composite material causes a notable release of hazardous substances from the process zone, amongst others carbon fiber segments or fibrous particles. In this work, amounts and geometries of the released fiber segments are analyzed and discussed in terms of their hazardous potential. Moreover, it is investigated to what extent gaseous organic process emissions are adsorbed at the fiber segments, similar to an adsorption of volatile organic compounds at activated carbon, which is typically used as filter material.
Environmental health program activities
NASA Technical Reports Server (NTRS)
Bergtholdt, C. P.
1969-01-01
Activities reported include studies on toxic air contaminants, excessive noise, poor lighting, food sanitation, water pollution, and exposure to nonionizing radiation as health hazards. Formulations for a radiological health manual provide guidance to personnel in the procurement and safe handling of radiation producing equipment and Apollo mission planning. A literature search and development of a water analysis laboratory are outlined to obtain information regarding microbiological problems involving potable water, waste management, and personal hygiene.
Environmental Assessment for North Warning System (Alaska)
1986-11-10
With Respect to Human Exposure to Radio Frequency Electromagnetic Fields , 300 kHz to 100 GHz, ANSI C95.1-1982, IEEE, New York. CH 2M Hill, 1981...Council on Radiation Protection and Measurements), 1986.Biological Effects and Exposure Criteria for Radiofrequency Electromagnetic Fields . NCRP Report...6 4.1.3.1 Radiofrequency Radiation ..................... 4-7 4.1.3.1.1 Electromagnetic Hazards.......... 4-7 4.1.3.1.2 Electromagnetic Interference
14 CFR 417.409 - System hazard controls.
Code of Federal Regulations, 2010 CFR
2010-01-01
..., or system must account for static and dynamic loads, environmental stresses, and expected wear; (3... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false System hazard controls. 417.409 Section 417... OF TRANSPORTATION LICENSING LAUNCH SAFETY Ground Safety § 417.409 System hazard controls. (a) General...
A hazard control system for robot manipulators
NASA Technical Reports Server (NTRS)
Carter, Ruth Chiang; Rad, Adrian
1991-01-01
A robot for space applications will be required to complete a variety of tasks in an uncertain, harsh environment. This fact presents unusual and highly difficult challenges to ensuring the safety of astronauts and keeping the equipment they depend on from becoming damaged. The systematic approach being taken to control hazards that could result from introducing robotics technology in the space environment is described. First, system safety management and engineering principles, techniques, and requirements are discussed as they relate to Shuttle payload design and operation in general. The concepts of hazard, hazard category, and hazard control, as defined by the Shuttle payload safety requirements, is explained. Next, it is shown how these general safety management and engineering principles are being implemented on an actual project. An example is presented of a hazard control system for controlling one of the hazards identified for the Development Test Flight (DTF-1) of NASA's Flight Telerobotic Servicer, a teleoperated space robot. How these schemes can be applied to terrestrial robots is discussed as well. The same software monitoring and control approach will insure the safe operation of a slave manipulator under teleoperated or autonomous control in undersea, nuclear, or manufacturing applications where the manipulator is working in the vicinity of humans or critical hardware.
NASA Technical Reports Server (NTRS)
Watson, Clifford
2010-01-01
Traditional hazard analysis techniques utilize a two-dimensional representation of the results determined by relative likelihood and severity of the residual risk. These matrices present a quick-look at the Likelihood (Y-axis) and Severity (X-axis) of the probable outcome of a hazardous event. A three-dimensional method, described herein, utilizes the traditional X and Y axes, while adding a new, third dimension, shown as the Z-axis, and referred to as the Level of Control. The elements of the Z-axis are modifications of the Hazard Elimination and Control steps (also known as the Hazard Reduction Precedence Sequence). These steps are: 1. Eliminate risk through design. 2. Substitute less risky materials for more hazardous materials. 3. Install safety devices. 4. Install caution and warning devices. 5. Develop administrative controls (to include special procedures and training.) 6. Provide protective clothing and equipment. When added to the twodimensional models, the level of control adds a visual representation of the risk associated with the hazardous condition, creating a tall-pole for the least-well-controlled failure while establishing the relative likelihood and severity of all causes and effects for an identified hazard. Computer modeling of the analytical results, using spreadsheets and threedimensional charting gives a visual confirmation of the relationship between causes and their controls
NASA Technical Reports Server (NTRS)
Watson, Clifford C.
2011-01-01
Traditional hazard analysis techniques utilize a two-dimensional representation of the results determined by relative likelihood and severity of the residual risk. These matrices present a quick-look at the Likelihood (Y-axis) and Severity (X-axis) of the probable outcome of a hazardous event. A three-dimensional method, described herein, utilizes the traditional X and Y axes, while adding a new, third dimension, shown as the Z-axis, and referred to as the Level of Control. The elements of the Z-axis are modifications of the Hazard Elimination and Control steps (also known as the Hazard Reduction Precedence Sequence). These steps are: 1. Eliminate risk through design. 2. Substitute less risky materials for more hazardous materials. 3. Install safety devices. 4. Install caution and warning devices. 5. Develop administrative controls (to include special procedures and training.) 6. Provide protective clothing and equipment. When added to the two-dimensional models, the level of control adds a visual representation of the risk associated with the hazardous condition, creating a tall-pole for the least-well-controlled failure while establishing the relative likelihood and severity of all causes and effects for an identified hazard. Computer modeling of the analytical results, using spreadsheets and three-dimensional charting gives a visual confirmation of the relationship between causes and their controls.
Risk Presentation Using the Three Dimensions of Likelihood, Severity, and Level of Control
NASA Technical Reports Server (NTRS)
Watson, Clifford
2010-01-01
Traditional hazard analysis techniques utilize a two-dimensional representation of the results determined by relative likelihood and severity of the residual risk. These matrices present a quick-look at the Likelihood (Y-axis) and Severity (X-axis) of the probable outcome of a hazardous event. A three-dimensional method, described herein, utilizes the traditional X and Y axes, while adding a new, third dimension, shown as the Z-axis, and referred to as the Level of Control. The elements of the Z-axis are modifications of the Hazard Elimination and Control steps (also known as the Hazard Reduction Precedence Sequence). These steps are: 1. Eliminate risk through design. 2. Substitute less risky materials for more hazardous materials. 3. Install safety devices. 4. Install caution and warning devices. 5. Develop administrative controls (to include special procedures and training.) 6. Provide protective clothing and equipment. When added to the two-dimensional models, the level of control adds a visual representation of the risk associated with the hazardous condition, creating a tall-pole for the leastwell-controlled failure while establishing the relative likelihood and severity of all causes and effects for an identified hazard. Computer modeling of the analytical results, using spreadsheets and three-dimensional charting gives a visual confirmation of the relationship between causes and their controls.
Risk assessment in infrastructure in educational institution: A study in Malaysia
NASA Astrophysics Data System (ADS)
Rasdan Ismail, Ahmad; Adilah Hamzah, Noor; Kamilah Makhtar, Nor; Azhar Mat Daud, Khairul; Zulkarnaen Khidzir, Nik; Husna Che Hassan, Nurul; Arifpin Mansor, Muhamad
2017-10-01
This particular study was conducted to assess the hazard exposure in education institution and to highlight the possible risk level available. The assessment utilised is Hazard Identification, Risk Assessment and Risk Control (HIRARC). There was a 2008’s form in order to determine the risk level of the hazard. There were over 111 of education institutions were selected around Malaysia to perform this assessment. Area chosen for each institution was office, playing field, canteen, classroom, toilet and drainage. By referring HIRARC Guideline 2008, the determination of risk rank is measure based on the formula likelihood multiply severity and the rank need to refer from risk matrix standard. There are several hazard have be found and shows the high, medium and low of risk level. The higher level of risk was discussed in the study which is hazard found in playing field and hazard in office. There several hazard that need to be control by education management to avoid increase of case accident in Education Sector, Malaysia. As conclusion, the exposure hazard among the staff and educators is high and further action and control are needed. Further study need to explore the best recommendation for control measure of the hazard exposed by education institution.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-20
... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5603-N-93] Healthy Home and Lead Hazard... collection is designed to provide HUD timely information on progress of Healthy Homes Demonstration Program, Healthy Homes Technical Studies Program, Lead Base paint Hazard Control program, Lead Hazard Reduction...
LeBlanc, John C.; Pless, I. Barry; King, W. James; Bawden, Harry; Bernard-Bonnin, Anne-Claude; Klassen, Terry; Tenenbein, Milton
2006-01-01
Background Young children may sustain injuries when exposed to certain hazards in the home. To better understand the relation between several childproofing strategies and the risk of injuries to children in the home, we undertook a multicentre case–control study in which we compared hazards in the homes of children with and without injuries. Methods We conducted this case-control study using records from 5 pediatric hospital emergency departments for the 2-year period 1995–1996. The 351 case subjects were children aged 7 years and less who presented with injuries from falls, burns or scalds, ingestions or choking. The matched control subjects were children who presented during the same period with acute non-injury-related conditions. A home visitor, blinded to case-control status, assessed 19 injury hazards at the children's homes. Results Hazards found in the homes included baby walkers (21% of homes with infants), no functioning smoke alarm (17% of homes) and no fire extinguisher (51% of homes). Cases did not differ from controls in the mean proportion of home hazards. After controlling for siblings, maternal education and employment, we found that cases differed from controls for 5 hazards: the presence of a baby walker (odds ratio [OR] 9.0, 95% confidence interval [CI] 1.1–71.0), the presence of choking hazards within a child's reach (OR 2.0, 95% CI 1.0–3.7), no child-resistant lids in bathroom (OR 1.6, 95% CI 1.0–2.5), no smoke alarm (OR 3.2, 95% CI 1.4–7.7) and no functioning smoke alarm (OR 1.7, 95% CI 1.0–2.8). Interpretation Homes of children with injuries differed from those of children without injuries in the proportions of specific hazards for falls, choking, poisoning and burns, with a striking difference noted for the presence of a baby walker. In addition to counselling parents about specific hazards, clinicians should consider that the presence of some hazards may indicate an increased risk for home injuries beyond those directly related to the hazard found. Families with any home hazard may be candidates for interventions to childproof against other types of home hazards. PMID:16998079
Sustainably Sourced, Thermally Resistant, Radiation Hard Biopolymer
NASA Technical Reports Server (NTRS)
Pugel, Diane
2011-01-01
This material represents a breakthrough in the production, manufacturing, and application of thermal protection system (TPS) materials and radiation shielding, as this represents the first effort to develop a non-metallic, non-ceramic, biomaterial-based, sustainable TPS with the capability to also act as radiation shielding. Until now, the standing philosophy for radiation shielding involved carrying the shielding at liftoff or utilizing onboard water sources. This shielding material could be grown onboard and applied as needed prior to different radiation landscapes (commonly seen during missions involving gravitational assists). The material is a bioplastic material. Bioplastics are any combination of a biopolymer and a plasticizer. In this case, the biopolymer is a starch-based material and a commonly accessible plasticizer. Starch molecules are composed of two major polymers: amylase and amylopectin. The biopolymer phenolic compounds are common to the ablative thermal protection system family of materials. With similar constituents come similar chemical ablation processes, with the potential to have comparable, if not better, ablation characteristics. It can also be used as a flame-resistant barrier for commercial applications in buildings, homes, cars, and heater firewall material. The biopolymer is observed to undergo chemical transformations (oxidative and structural degradation) at radiation doses that are 1,000 times the maximum dose of an unmanned mission (10-25 Mrad), indicating that it would be a viable candidate for robust radiation shielding. As a comparison, the total integrated radiation dose for a three-year manned mission to Mars is 0.1 krad, far below the radiation limit at which starch molecules degrade. For electron radiation, the biopolymer starches show minimal deterioration when exposed to energies greater than 180 keV. This flame-resistant, thermal-insulating material is non-hazardous and may be sustainably sourced. It poses no hazardous waste threats during its lifecycle. The material composition is radiation-tolerant up to megarad doses, indicating its use as a radiation shielding material. It is lightweight, non-metallic, and able to be mechanically densified, permitting a tunable gradient of thermal and radiation protection as needed. The dual-use (thermal and radiation shielding), sustainable nature of this material makes it suitable for both industrial applications as a sustainable/green building material, and for space applications as thermal protection material and radiation shield.
An Analysis of U.S. Army Health Hazard Assessments During the Acquisition of Military Materiel
2010-06-03
GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S...administrative controls and the use of personal protective equipment (PPE) (Milz, Conrad, & Soule , 2003). Engineering controls can eliminate hazards through...facilitate hazard free designs or conditions (Milz, Conrad, & Soule , 2003). Engineering control measures can serve to 7 minimize hazards where they
Mora, Juan C; Baeza, Antonio; Robles, Beatriz; Sanz, Javier
2016-06-05
Naturally Occurring Radioactive Materials (NORM) wastes are generated in huge quantities in several industries and their management has been carried out under considerations of industrial non-radioactive wastes, before the concern on the radioactivity content was included in the legislation. Therefore these wastes were conditioned using conventional methods and the waste disposals were designed to isolate toxic elements from the environment for long periods of time. Spanish regulation for these conventional toxic waste disposals includes conditions that assure adequate isolation to minimize the impact of the wastes to the environment in present and future conditions. After 1996 the radiological impact of the management of NORM wastes is considered and all the aspects related with natural radiations and the radiological control regarding the management of residues from NORM industries were developed in the new regulation. One option to be assessed is the disposal of NORM wastes in hazardous and non-hazardous waste disposals, as was done before this new regulation. This work analyses the management of NORM wastes in these landfills to derive the masses that can be disposed without considerable radiological impact. Generic dose assessments were carried out under highly conservative hypothesis and a discussion on the uncertainty and variability sources was included to provide consistency to the calculations. Copyright © 2016 Elsevier B.V. All rights reserved.
Enhanced control and sensing for the REMOTEC ANDROS Mk VI robot. CRADA final report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Spelt, P.F.; Harvey, H.W.
1998-08-01
This Cooperative Research and Development Agreement (CRADA) between Lockheed Martin Energy Systems, Inc., and REMOTEC, Inc., explored methods of providing operator feedback for various work actions of the ANDROS Mk VI teleoperated robot. In a hazardous environment, an extremely heavy workload seriously degrades the productivity of teleoperated robot operators. This CRADA involved the addition of computer power to the robot along with a variety of sensors and encoders to provide information about the robot`s performance in and relationship to its environment. Software was developed to integrate the sensor and encoder information and provide control input to the robot. ANDROS Mkmore » VI robots are presently used by numerous electric utilities to perform tasks in reactors where substantial exposure to radiation exists, as well as in a variety of other hazardous environments. Further, this platform has potential for use in a number of environmental restoration tasks, such as site survey and detection of hazardous waste materials. The addition of sensors and encoders serves to make the robot easier to manage and permits tasks to be done more safely and inexpensively (due to time saved in the completion of complex remote tasks). Prior research on the automation of mobile platforms with manipulators at Oak Ridge National Laboratory`s Center for Engineering Systems Advanced Research (CESAR, B&R code KC0401030) Laboratory, a BES-supported facility, indicated that this type of enhancement is effective. This CRADA provided such enhancements to a successful working teleoperated robot for the first time. Performance of this CRADA used the CESAR laboratory facilities and expertise developed under BES funding.« less
[Medium-term forecast of solar cosmic rays radiation risk during a manned Mars mission].
Petrov, V M; Vlasov, A G
2006-01-01
Medium-term forecasting radiation hazard from solar cosmic rays will be vital in a manned Mars mission. Modern methods of space physics lack acceptable reliability in medium-term forecasting the SCR onset and parameters. The proposed estimation of average radiation risk from SCR during the manned Mars mission is made with the use of existing SCR fluence and spectrum models and correlation of solar particle event frequency with predicted Wolf number. Radiation risk is considered an additional death probability from acute radiation reactions (ergonomic component) or acute radial disease in flight. The algorithm for radiation risk calculation is described and resulted risk levels for various periods of the 23-th solar cycle are presented. Applicability of this method to advance forecasting and possible improvements are being investigated. Recommendations to the crew based on risk estimation are exemplified.
Overview of the Martian radiation environment experiment
NASA Technical Reports Server (NTRS)
Zeitlin, C.; Cleghorn, T.; Cucinotta, F.; Saganti, P.; Andersen, V.; Lee, K.; Pinsky, L.; Atwell, W.; Turner, R.; Badhwar, G.
2004-01-01
Space radiation presents a hazard to astronauts, particularly those journeying outside the protective influence of the geomagnetosphere. Crews on future missions to Mars will be exposed to the harsh radiation environment of deep space during the transit between Earth and Mars. Once on Mars, they will encounter radiation that is only slightly reduced, compared to free space, by the thin Martian atmosphere. NASA is obliged to minimize, where possible, the radiation exposures received by astronauts. Thus, as a precursor to eventual human exploration, it is necessary to measure the Martian radiation environment in detail. The MARIE experiment, aboard the 2001 Mars Odyssey spacecraft, is returning the first data that bear directly on this problem. Here we provide an overview of the experiment, including introductory material on space radiation and radiation dosimetry, a description of the detector, model predictions of the radiation environment at Mars, and preliminary dose-rate data obtained at Mars. c2003 COSPAR. Published by Elsevier Ltd. All rights reserved.
ERIC Educational Resources Information Center
Zavon, Mitchell R.
1970-01-01
To improve the general environment, the author stresses the need to preserve and protect our natural resources of water, air, and food. The problems of population growth, radiation hazards, pesticides, noise pollution, and waste disposal are also discussed. Bibliographies. (LC)
Federal Register 2010, 2011, 2012, 2013, 2014
2010-02-24
... 0584-AD65 School Food Safety Program Based on Hazard Analysis and Critical Control Point Principles... Safety Program Based on Hazard Analysis and Critical Control Point Principles (HACCP) was published on... of Management and Budget (OMB) cleared the associated information collection requirements (ICR) on...
Radiation risk and nuclear medicine: An interview with a Nobel Prize winner
DOE Office of Scientific and Technical Information (OSTI.GOV)
Yalow, R.S.
1995-12-01
In a speech given years ago at the Veterans Administration Medical Center, Bronx, NY, Rosalyn S. Yalow, 1977 Nobel Prize recipient for her invention of radioimmunoassay, made several salient points on the perception of fear or hazards from exposure to low-level radiation and low-level radioactive wastes. For the past three years, Yalow has been concerned with the general fear of radiation. In this interview, Newsline solicited Yalow`s views on public perceptions on radiation risk and what the nuclear medicine community can do to emphasize the fact that, if properly managed, the use of isotopes in medicine and other cases ismore » not dangerous.« less
Manpower Needs in Environmental Engineering
ERIC Educational Resources Information Center
Middlebrooks, E. J.; And Others
1974-01-01
Outlines manpower needs in both the public and private sectors in the areas of air pollution control, solid waste management, radiological hazard control, pesticide hazard control, and water pollution control. (GS)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dorth, Jennifer A., E-mail: jennifer.dorth@duke.edu; Prosnitz, Leonard R.; Broadwater, Gloria
2012-11-01
Purpose: While consolidation radiation therapy (i.e., RT administered after chemotherapy) is routine treatment for patients with early-stage diffuse large B-cell lymphoma (DLBCL), the role of consolidation RT in stage III-IV DLBCL is controversial. Methods and Materials: Cases of patients with stage III-IV DLBCL treated from 1991 to 2009 at Duke University, who achieved a complete response to chemotherapy were reviewed. Clinical outcomes were calculated using the Kaplan-Meier method and were compared between patients who did and did not receive RT, using the log-rank test. A multivariate analysis was performed using Cox proportional hazards model. Results: Seventy-nine patients were identified. Chemotherapymore » (median, 6 cycles) consisted of anti-CD20 antibody rituximab combined with cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP; 65%); cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP; 22%); or other (13%). Post-chemotherapy imaging consisted of positron emission tomography (PET)/computed tomography (CT) (73%); gallium with CT (14%); or CT only (13%). Consolidation RT (median, 25 Gy) was given to involved sites of disease in 38 (48%) patients. Receipt of consolidation RT was associated with improved in-field control (92% vs. 69%, respectively, p = 0.028) and event-free survival (85% vs. 65%, respectively, p = 0.014) but no difference in overall survival (85% vs. 78%, respectively, p = 0.15) when compared to patients who did not receive consolidation RT. On multivariate analysis, no RT was predictive of increased risk of in-field failure (hazard ratio [HR], 8.01, p = 0.014) and worse event-free survival (HR, 4.3, p = 0.014). Conclusions: Patients with stage III-IV DLBCL who achieve negative post-chemotherapy imaging have improved in-field control and event-free survival with low-dose consolidation RT.« less
Radiation with or without Antiandrogen Therapy in Recurrent Prostate Cancer
Shipley, W.U.; Seiferheld, W.; Lukka, H.R.; Major, P.P.; Heney, N.M.; Grignon, D.J.; Sartor, O.; Patel, M.P.; Bahary, J.-P.; Zietman, A.L.; Pisansky, T.M.; Zeitzer, K.L.; Lawton, C.A.F.; Feng, F.Y.; Lovett, R.D.; Balogh, A.G.; Souhami, L.; Rosenthal, S.A.; Kerlin, K.J.; Dignam, J.J.; Pugh, S.L.; Sandler, H.M.
2017-01-01
BACKGROUND Salvage radiation therapy is often necessary in men who have undergone radical pros-tatectomy and have evidence of prostate-cancer recurrence signaled by a persistently or recurrently elevated prostate-specific antigen (PSA) level. Whether antiandrogen therapy with radiation therapy will further improve cancer control and prolong overall survival is unknown. METHODS In a double-blind, placebo-controlled trial conducted from 1998 through 2003, we assigned 760 eligible patients who had undergone prostatectomy with a lymphadenectomy and had disease, as assessed on pathological testing, with a tumor stage of T2 (confined to the prostate but with a positive surgical margin) or T3 (with histologic extension beyond the prostatic capsule), no nodal involvement, and a detectable PSA level of 0.2 to 4.0 ng per milliliter to undergo radiation therapy and receive either antiandrogen therapy (24 months of bicalutamide at a dose of 150 mg daily) or daily placebo tablets during and after radiation therapy. The primary end point was the rate of overall survival. RESULTS The median follow-up among the surviving patients was 13 years. The actuarial rate of overall survival at 12 years was 76.3% in the bicalutamide group, as compared with 71.3% in the placebo group (hazard ratio for death, 0.77; 95% confidence interval, 0.59 to 0.99; P=0.04). The 12-year incidence of death from prostate cancer, as assessed by means of central review, was 5.8% in the bicalutamide group, as compared with 13.4% in the placebo group (P<0.001). The cumulative incidence of metastatic prostate cancer at 12 years was 14.5% in the bicalutamide group, as compared with 23.0% in the placebo group (P=0.005). The incidence of late adverse events associated with radiation therapy was similar in the two groups. Gynecomastia was recorded in 69.7% of the patients in the bicalutamide group, as compared with 10.9% of those in the placebo group (P<0.001). CONCLUSIONS The addition of 24 months of antiandrogen therapy with daily bicalutamide to salvage radiation therapy resulted in significantly higher rates of long-term overall survival and lower incidences of metastatic prostate cancer and death from prostate cancer than radiation therapy plus placebo. (Funded by the National Cancer Institute and AstraZeneca; RTOG 9601 ClinicalTrials.gov number, NCT00002874.) PMID:28146658
Radiation safety analysis of the ISS bone densitometer
NASA Astrophysics Data System (ADS)
Todd, Paul; Vellinger, John C.; Barton, Kenneth; Faget, Paul
A Bone Densitometer (BD) has been developed for installation on the International Space Station (ISS) with delivery by the Space-X Dragon spacecraft planned for mid 2014. After initial tests on orbit the BD will be used in longitudinal measurements of bone mineral density in experimental mice as a means of evaluating countermeasures to bone loss. The BD determines bone mineral density (and other radiographic parameters) by dual energy x-ray absorptiometry (DEXA). In a single mouse DEXA “scan” its 80 kV x-ray tube is operated for 15 seconds at 35 kV and 3 seconds at 80 kV in four repetitions, giving the subject a total dose of 2.5 mSv. The BD is a modification of a commercial mouse DEXA product known as PIXImus(TM). Before qualifying the BD for utilization on ISS it was necessary to evaluate its radiation safety features and any level of risk to ISS crew members. The BD design reorients the PIXImus so that it fits in an EXPRESS locker on ISS with the x-ray beam directed into the crew aisle. ISS regulation SSP 51700 considers the production of ionizing radiation to be a catastrophic-level hazard. Accidental exposure is prevented by three independent levels of on-off control as required for a catastrophic hazard. The ALARA (As Low as Reasonably Achievable) principle was applied to the BD hazard just as would be done on the ground, so deliberate exposure is limited by lead shielding according to ALARA. Hot spots around the BD were identified by environmental dosimetry using a Ludlum 9DP pressurized ionization chamber survey meter. Various thicknesses of lead were applied to the BD housing in areas where highest dose-per-scan readings were made. It was concluded that 0.4 mm of lead shielding at strategic locations, adding only a few kg of mass to the payload, would accomplish ALARA. With shielding in place the BD now exposes a crew member floating 40 cm away to less than 0.08 microSv per mouse scan. There is an upper limit of 20 scans per day, or 1.6 microSv per day, which may occur a few times per year. This dose may be compared with the 400 microSv per day received by crew members in low earth orbit. The designed shielding level also protects adjacent payloads by maintaining less than 2 mrad/day at 5 cm - a requirement for the protection of electronic instrumentation. It is concluded that the ISS Bone Densitometer minimizes ionizing radiation risks associated with its operation. Research supported by NASA Contract NNJ13GA01C and the Center for the Advancement of Science in Space (CASIS).
Design reuse experience of space and hazardous operations robots
NASA Technical Reports Server (NTRS)
Oneil, P. Graham
1994-01-01
A comparison of design drivers for space and hazardous nuclear waste operating robots details similarities and differences in operations, performance and environmental parameters for these critical environments. The similarities are exploited to provide low risk system components based on reuse principles and design knowledge. Risk reduction techniques are used for bridging areas of significant differences. As an example, risk reduction of a new sensor design for nuclear environment operations is employed to provide upgradeable replacement units in a reusable architecture for significantly higher levels of radiation.
Health hazards of ceramic artists.
Dorevitch, S; Babin, A
2001-01-01
Ceramic artists can be exposed to many hazards including metals (such as lead), fibrogenic dusts (such as silica), heat, repetitive motion, radiation, and toxic emissions from kilns. The health risks of these exposures have not been well characterized among artists, although limited information is available from commercial potteries. Adverse health effects may be prevented by using less hazardous materials (such as lead-free glazes), improved ventilation, and proper work practices. Special precautions must be in place if children have access to the ceramics studio. The use of glazed ceramic dishes can be a risk for lead toxicity. Food should not be stored in glazed ceramics, and pregnant women should avoid daily use of ceramic mugs for drinking hot beverages.
Occupational health hazards in the interventional laboratory: time for a safer environment.
Klein, Lloyd W; Miller, Donald L; Balter, Stephen; Laskey, Warren; Haines, David; Norbash, Alexander; Mauro, Matthew A; Goldstein, James A
2009-07-01
This document is a consensus statement by the major American societies of physicians who work in the interventional laboratory environment. It reviews available data on the prevalence of occupational health risks and summarizes ongoing epidemiologic studies designed to further elucidate these risks. Its purpose is to affirm that the interventional laboratory poses workplace hazards that must be acknowledged, better understood, and mitigated to the greatest extent possible. Vigorous efforts are advocated to reduce these hazards. Interventional physicians and their professional societies, working together with industry, should strive toward minimizing operator radiation exposure, eliminating the need for personal protective apparel, and ending the orthopedic and ergonomic consequences of the interventional laboratory work environment.
Occupational health hazards in the interventional laboratory: time for a safer environment.
Klein, Lloyd W; Miller, Donald L; Balter, Stephen; Laskey, Warren; Haines, David; Norbash, Alexander; Mauro, Matthew A; Goldstein, James A
2009-02-15
This document is a consensus statement by the major American societies of physicians who work in the interventional laboratory environment. It reviews available data on the prevalence of occupational health risks and summarizes ongoing epidemiologic studies designed to further elucidate these risks. Its purpose is to affirm that the interventional laboratory poses workplace hazards that must be acknowledged, better understood, and mitigated to the greatest extent possible. Vigorous efforts are advocated to reduce these hazards. Interventional physicians and their professional societies, working together with industry, should strive toward minimizing operator radiation exposure, eliminating the need for personal protective apparel, and ending the orthopedic and ergonomic consequences of the interventional laboratory work environment. Copyright SIR, 2009
Occupational health hazards in the interventional laboratory: time for a safer environment.
Klein, Lloyd W; Miller, Donald L; Balter, Stephen; Laskey, Warren; Haines, David; Norbash, Alexander; Mauro, Matthew A; Goldstein, James A
2009-02-01
This document is a consensus statement by the major American societies of physicians who work in the interventional laboratory environment. It reviews available data on the prevalence of occupational health risks and summarizes ongoing epidemiologic studies designed to further elucidate these risks. Its purpose is to affirm that the interventional laboratory poses workplace hazards that must be acknowledged, better understood, and mitigated to the greatest extent possible. Vigorous efforts are advocated to reduce these hazards. Interventional physicians and their professional societies, working together with industry, should strive toward minimizing operator radiation exposure, eliminating the need for personal protective apparel, and ending the orthopedic and ergonomic consequences of the interventional laboratory work environment.
NASA Astrophysics Data System (ADS)
Zhang, Jingjing; Xie, Bin; Yu, Xingjian; Luo, Xiaobing; Zhang, Tao; Liu, Shishen; Yu, Zhihua; Liu, Li; Jin, Xing
2017-07-01
In this study, the blue light hazard performances of phosphor converted-light-emitting diodes (pc-LEDs) with red phosphor and red quantum dots (QDs) were compared and analyzed by spectral optimization, which boosts the minimum attainable blue light hazard efficiency of radiation (BLHER) at high values of color rendering index (CRI) and luminous efficacy of radiation (LER) when the correlated color temperature (CCT) value changes from 1800 to 7800 K. It is found that the minimal BLHER value increases with the increase in the CCT value, and the minimal BLHER values of the two spectral models are nearly the same. Note that the QDs' model has advantages at CCT coverage under the same constraints of CRI and LER. Then, the relationships between minimal BLHER, CRI, CCT, and LER of pc-LEDs with QDs' model were analyzed. It is found that the minimal BLHER values are nearly the same when the CRI value changes from 50 to 90. Therefore, the influence of CRI on minimal BLHER is insignificant. Minimal BLHER increases with the increase in the LER value from 240 to 360 lm/W.
Fadol, Nooreldin; Idriss, Hajo; Salih, Isam; Ragab, Nserdin A; Osman, Safa; Sam, Adam K
2018-06-01
This study was conducted to assess the level of radioactivity and the radiation hazards associated with granite rocks used for construction of buildings. The measurement of radioactivity content of the rock samples was performed with gamma-spectrometry equipped with Nal (TI) detector. From the results obtained in this study the average activity concentrations of 226Ra, 232Th and 40K were 20.64, 30.50 and 295.19 Bq kg-1, respectively. The absorbed dose rate in air at 1 m above ground level, the annual effective dose and the gamma index were determined with the aim to assess the possible radiological impact on inhabitants of dwellings built using such rocks. The mean value of the absorbed dose rate, the annual effective dose and the gamma index (Iγ) was 36.36 nGy h-1, 40.79 μSv y-1 and 0.51 μSv y-1, respectively. Radium equivalent activities, and external and internal hazard indices, were also calculated. These data indicated that the area of study lies within areas recognized as normal background radiation and the granite rocks are safe to be used as building material and other structural purposes.
Comparison of Measured vs Modeled TE and TM Field Penetration into a Slotted Circular Cylinder
2011-01-01
1. INTRODUCTION In the testing of military systems and subsystems for electromag- netic vulnerability (EMV) and hazards of electromagnetic radiation ...to ordnance ( HERO ), extremely high amplitude (peak and rms) elec- tromagnetic fields must be generated and radiated to immerse the sys- tem/subsystem...Progress In Electromagnetics Research B, Vol. 28, 201–218, 2011 COMPARISON OF MEASURED VS. MODELED TE AND TM FIELD PENETRATION INTO A SLOTTED
Why NASA and the Space Electronics Community Cares About Cyclotrons
NASA Technical Reports Server (NTRS)
LaBel, Kenneth A.
2017-01-01
NASA and the space community are faced with the harsh reality of operating electronic systems in the space radiation environment. Systems need to work reliably (as expected for as long as expected) and be available during critical operations such as docking or firing a thruster. This talk will provide a snapshot of the import of ground-based research on the radiation performance of electronics. Discussion topics include: 1) The space radiation environment hazard, 2) Radiation effects on electronics, 3) Simulation of effects with cyclotrons (and other sources), 4) Risk prediction for space missions, and, 5) Real-life examples of both ground-based testing and space-based anomalies and electronics performance. The talk will conclude with a discussion of the current state of radiation facilities in North America for ground-based electronics testing.
Mars' surface radiation environment measured with the Mars Science Laboratory's Curiosity rover.
Hassler, Donald M; Zeitlin, Cary; Wimmer-Schweingruber, Robert F; Ehresmann, Bent; Rafkin, Scot; Eigenbrode, Jennifer L; Brinza, David E; Weigle, Gerald; Böttcher, Stephan; Böhm, Eckart; Burmeister, Soenke; Guo, Jingnan; Köhler, Jan; Martin, Cesar; Reitz, Guenther; Cucinotta, Francis A; Kim, Myung-Hee; Grinspoon, David; Bullock, Mark A; Posner, Arik; Gómez-Elvira, Javier; Vasavada, Ashwin; Grotzinger, John P
2014-01-24
The Radiation Assessment Detector (RAD) on the Mars Science Laboratory's Curiosity rover began making detailed measurements of the cosmic ray and energetic particle radiation environment on the surface of Mars on 7 August 2012. We report and discuss measurements of the absorbed dose and dose equivalent from galactic cosmic rays and solar energetic particles on the martian surface for ~300 days of observations during the current solar maximum. These measurements provide insight into the radiation hazards associated with a human mission to the surface of Mars and provide an anchor point with which to model the subsurface radiation environment, with implications for microbial survival times of any possible extant or past life, as well as for the preservation of potential organic biosignatures of the ancient martian environment.
Smina, T P; Maurya, D K; Devasagayam, T P A; Janardhanan, K K
2015-05-25
The total triterpenes isolated from the fruiting bodies of Ganoderma lucidum was examined for its potential to prevent γ-radiation induced membrane damage in rat liver mitochondria and microsomes. The effects of total triterpenes on γ-radiation-induced DNA strand breaks in pBR 322 plasmid DNA in vitro and human peripheral blood lymphocytes ex vivo were evaluated. The protective effect of total triterpenes against γ-radiation-induced micronuclei formations in mice bone marrow cells in vivo were also evaluated. The results indicated the significant effectiveness of Ganoderma triterpenes in protecting the DNA and membrane damages consequent to the hazardous effects of radiation. The findings suggest the potential use of Ganoderma triterpenes in radio therapy. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Rajasekaran, Ramu; Bergamo Lopes, Monica; Magrini, Taciana D.; Figueira Lopes Cançado, Ana Clara; Abrahao Martin, Airton
2017-02-01
Stratum Corneum is the outer covering of the body, which serves as a barrier to infection. The composition of the skin changes withexternal environmental factors, such as temperature, sun irradiation, air pollutants, chemical hazards, as well as other factors.Solar radiation,especially IR radiation is being used as medicine for wound healing processes, in cosmetology, in physiotherapy and warming of muscles. Also, it was reported that the IR radiation produces free radicals and the excess production of free radicals causes irreversible damages. It has been reported that heat may be transmitted by IR radiation, which results in raised skin temperature and the chronic heat exposure of human skin may cause alterations. Erythema igne is one such disease known to be caused by chronic heat exposure. Many techniques have been adopted for monitoring the changes in the skin, which includes the tape stripping and biopsy as the primary methodology. However, these in vitro techniques are invasive, time consuming, and may not provide the actual information as in in vivo conditions. Confocal Raman spectroscopy,which is non-invasive and real time was considered as a potential tool for the in vivo analysis of the distribution and characteristics of different metabolic conditions and their variations of the skin. In this regard, we aimed at in vivo characterization of the IR induced changes in the stratum corneum of human volunteers. The results of Raman spectral signatures with respect to the control and IR exposed skin will be discussed.
Monitoring millimeter wave stray radiation during ECRH operation at ASDEX Upgrade
NASA Astrophysics Data System (ADS)
Schubert, M.; Honecker, F.; Monaco, F.; Schmid-Lorch, D.; Schütz, H.; Stober, J.; Wagner, D.
2012-09-01
Due to imperfection of the single path absorption, ECRH at ASDEX Upgrade (AUG) is always accompanied by stray radiation in the vacuum vessel. New ECRH scenarios with O2 and X3 heating schemes extend the operational space, but they have also the potential to increase the level of stray radiation. There are hazards for invessel components. Damage on electric cables has already been encountered. It is therefore necessary to monitor and control the ECRH with respect to the stray radiation level. At AUG a system of Sniffer antennas equipped with microwave detection diodes is installed. The system is part of the ECRH interlock circuit. We notice, however, that during plasma operation the variations of the Sniffer antenna signal are very large. In laboratory measurements we see variations of up to 20 dB in the directional sensitivity and we conclude that an interference pattern is formed inside the copper sphere of the antenna. When ECRH is in plasma operation at AUG, the plasma is acting as a phase and mode mixer for the millimeter waves and thus the interference pattern inside the sphere changes with the characteristic time of the plasma dynamics. In order to overcome the difficulty of a calibrated measurement of the average stray radiation level, we installed bolometer and pyroelectric detectors, which intrinsically average over interference structures due to their large active area. The bolometer provides a robust calibration but with moderate temporal resolution. The pyroelectric detector provides high sensitivity and a good temporal resolution, but it raises issues of possible signal drifts in long pulses.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-02
... announced in a Federal Register notice published on May 22, 2009 for Lead Based Paint Hazard Control and... for the Lead Based Paint Hazard Control Grant Program under the Consolidated Appropriations Act, 2009... Tahoe, 1901 Airport Road, Suite 107, South Lake Tahoe, CA 96150, $1,500,000; State of Connecticut...
Medical Issues for a Human Mission to Mars and Martian Surface Expeditions
NASA Astrophysics Data System (ADS)
Jones, J. A.; Barratt, M.; Effenhauser, R.; Cockell, C. S.; Lee, P.
The medical issues for an exploratory class mission to Mars are myriad and challenging. They include hazards from the space environment, such as space vacuum and radiation; hazards on the planetary surface such as micrometeoroids and Martian dust, and constitutional medical hazards, like appendicitis and tooth abscess. They include hazards in the transit vehicle like foreign bodies and toxic atmospheres, and hazards in the habitat like decompression and combustion events. They also include human physiological adaptation to variable conditions of reduced gravity and prolonged isolation and confinement. The health maintenance program for a Mars mission will employ strategies of disease prevention, early detection, and contingency management, to mitigate the risks of spaceflight and exploration. Countermeasures for altered gravity conditions will allow crewmembers to maintain high levels of performance and nominal physiologic functioning. Despite all of these issues, given sufficient redundancy in on-board life support systems, there are no medical show-stoppers for the first human exploratory class missions.
Once-Daily Radiation Therapy for Inflammatory Breast Cancer
DOE Office of Scientific and Technical Information (OSTI.GOV)
Brown, Lindsay; Harmsen, William; Blanchard, Miran
2014-08-01
Purpose: Inflammatory breast cancer (IBC) is a rare and aggressive breast cancer variant treated with multimodality therapy. A variety of approaches intended to escalate the intensity and efficacy of radiation therapy have been reported, including twice-daily radiation therapy, dose escalation, and aggressive use of bolus. Herein, we examine our outcomes for patients treated with once-daily radiation therapy with aggressive bolus utilization, focusing on treatment technique. Methods and Materials: A retrospective review of patients with nonmetastatic IBC treated from January 1, 2000, through December 31, 2010, was performed. Locoregional control (LRC), disease-free survival (DFS), overall survival (OS) and predictors thereof weremore » assessed. Results: Fifty-two women with IBC were identified, 49 (94%) of whom were treated with neoadjuvant chemotherapy. All underwent mastectomy followed by adjuvant radiation therapy. Radiation was delivered in once-daily fractions of 1.8 to 2.25 Gy (median, 2 Gy). Patients were typically treated with daily 1-cm bolus throughout treatment, and 33 (63%) received a subsequent boost to the mastectomy scar. Five-year Kaplan Meier survival estimates for LRC, DFS, and OS were 81%, 56%, and 64%, respectively. Locoregional recurrence was associated with poorer OS (P<.001; hazard ratio [HR], 4.1). Extracapsular extension was associated with worse LRC (P=.02), DFS (P=.007), and OS (P=.002). Age greater than 50 years was associated with better DFS (P=.03). Pathologic complete response was associated with a trend toward improved LRC (P=.06). Conclusions: Once-daily radiation therapy with aggressive use of bolus for IBC results in outcomes consistent with previous reports using various intensified radiation therapy regimens. LRC remains a challenge despite modern systemic therapy. Extracapsular extension, age ≤50 years, and lack of complete response to chemotherapy appear to be associated with worse outcomes. Novel strategies are needed in IBC, particularly among these subsets of patients.« less
Swer, Rijied Thompson; Anbalagan, J.; Rajesh, Bhargavan
2017-01-01
Introduction The increasing scientific evidence of various health hazards on exposure of Radiofrequency Radiation (RFR) emitted from both the cell phones and base stations have caused significant media attention and public discussion in recent years. The mechanism of interaction of RF fields with developing tissues of children and fetuses may be different from that of adults due to their smaller physical size and variation in tissue electromagnetic properties. The present study may provide an insight into the basic mechanisms by which RF fields interact with developing tissues in an embryo. Aim To evaluate the possible tissue and DNA damage in developing liver of chick embryo following chronic exposure to Ultra-High Frequency/Radiofrequency Radiation (UHF/RFR) emitted from 2G and 3G cell phone. Materials and Methods Fertilized chick embryos were incubated in four groups. Group A-experimental group exposed to 2G radiation (60 eggs), Group B- experimental group exposed to 3G radiation (60 eggs), Group C- sham exposed control group (60 eggs) and Group D– control group (48 eggs). On completion of scheduled duration, the embryos were collected and processed for routine histological studies to check structural changes in liver. The nuclear diameter and karyorrhexis changes of hepatocytes were analysed using oculometer and square reticule respectively. The liver procured from one batch of eggs from all the four groups was subjected to alkaline comet assay technique to assess DNA damage. The results were compared using one-way ANOVA test. Results In our study, the exposure of developing chick embryos to 2G and 3G cell phone radiations caused structural changes in liver in the form of dilated sinusoidal spaces with haemorrhage, increased vacuolations in cytoplasm, increased nuclear diameter and karyorrhexis and significantly increased DNA damage. Conclusion The chronic exposure of chick embryo liver to RFR emitted from 2G and 3G cell phone resulted in various structural changes and DNA damage. The changes were more pronounced in 3G experimental group. Based on these findings it is necessary to create awareness among public about the possible ill effects of RFR exposure from cell phone. PMID:28892876
What views and uses of radiation sources in the 21st century?
Blix, H
2001-04-01
Considering that in 1899 neither biotechnology nor the electronic revolution were foreseen, some humility might be advisable when one looks into the crystal ball for the future role of radiation sources. In the past 50 years, nuclear medicine, nuclear weapons, and nuclear power have had a huge impact in the world. In the next 50 years, nuclear weapons may be phased out, nuclear power revived, and nuclear medicine may continue, especially for diagnostic purposes. Conflicts between great powers and blocks will no longer be about territorial or ideological domination but about trade, finance, information, and the environment and the weapons used will not be bombs but investments, credits, and control of information. Nuclear power-still based on fission-will be relaunched and get more uses, e.g., to propel ships, to produce heat for industry and for space heating, and perhaps to desalinate water. The public will be more at ease with radiation as it is better educated, as nuclear safety continuously improves and new types of nuclear power plants emerge, as waste sites fail to cause any problems, and as no other energy source is found to deliver so much energy at reasonable cost with negligible impact on climate and environment. One kilogram of oil corresponds to 4 kWh of electricity. One kilogram of uranium fuel corresponds to 50,000 kWh, and 1 kg of plutonium 6,000,000 kWh! In nuclear medicine, radiation may give way to other treatments as the understanding of cancer advances. On the other hand, the extreme ease with which sources of radiation can be identified is unmatched and likely to make them useful tools as tracers and markers in medicine-and other fields-for a long time. For certain uses--perhaps food irradiation--radiation sources, such as cobalt, may be replaced by accelerators which may be switched on and off at will. As more sources are used, registration and control of them must be made very effective around the whole world. Very high natural emissions of radon will continue to call for cautionary measures, but many other nonradiating substances will be identified as hazardous to health and call for vigorous intervention.
D'Silva, Mary Hydrina; Swer, Rijied Thompson; Anbalagan, J; Rajesh, Bhargavan
2017-07-01
The increasing scientific evidence of various health hazards on exposure of Radiofrequency Radiation (RFR) emitted from both the cell phones and base stations have caused significant media attention and public discussion in recent years. The mechanism of interaction of RF fields with developing tissues of children and fetuses may be different from that of adults due to their smaller physical size and variation in tissue electromagnetic properties. The present study may provide an insight into the basic mechanisms by which RF fields interact with developing tissues in an embryo. To evaluate the possible tissue and DNA damage in developing liver of chick embryo following chronic exposure to Ultra-High Frequency/Radiofrequency Radiation (UHF/RFR) emitted from 2G and 3G cell phone. Fertilized chick embryos were incubated in four groups. Group A-experimental group exposed to 2G radiation (60 eggs), Group B- experimental group exposed to 3G radiation (60 eggs), Group C- sham exposed control group (60 eggs) and Group D- control group (48 eggs). On completion of scheduled duration, the embryos were collected and processed for routine histological studies to check structural changes in liver. The nuclear diameter and karyorrhexis changes of hepatocytes were analysed using oculometer and square reticule respectively. The liver procured from one batch of eggs from all the four groups was subjected to alkaline comet assay technique to assess DNA damage. The results were compared using one-way ANOVA test. In our study, the exposure of developing chick embryos to 2G and 3G cell phone radiations caused structural changes in liver in the form of dilated sinusoidal spaces with haemorrhage, increased vacuolations in cytoplasm, increased nuclear diameter and karyorrhexis and significantly increased DNA damage. The chronic exposure of chick embryo liver to RFR emitted from 2G and 3G cell phone resulted in various structural changes and DNA damage. The changes were more pronounced in 3G experimental group. Based on these findings it is necessary to create awareness among public about the possible ill effects of RFR exposure from cell phone.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Inmuong, Uraiwan, E-mail: uraiwan@kku.ac.t; Faculty of Public Health, Khon Kaen University, Thailand 123 Mittrapharb Road, Khon Kaen 40002; Rithmak, Panee, E-mail: panrit@kku.ac.t
The Thai Public Health Act 1992 required the Thai local governments to issue respective regulations to take control of any possible health-hazard related activities, both from commercial and noncommercial sources. Since 1999, there has been centrally decentralized of power to a new form of local government establishment, namely Sub-district Administrative Organization (SAO). The SAO is asmall-scale local governing structure while its legitimate function is for community services, including control of health impact related activities. Most elected SAO administrators and officers are new and less experience with any of public health code of practice, particularly on health-hazard control. This action researchmore » attempted to introduce and apply a participatory health impact assessment (HIA) tool for the development of SAO health-hazard control regulation. The study sites were at Ban Meang and Kok See SAOs, Khon Kaen Province, Thailand, while all intervention activities conducted during May 2005-April 2006. A set of cooperative activities between researchers and community representatives were planned and organized by; surveying and identifying place and service base locally causing local environmental health problems, organizing community participatory workshops for drafting and proposing the health-hazard control regulation, and appropriate practices for health-hazard controlling measures. This action research eventually could successfully enable the SAO administrators and officers understanding of local environmental-related health problem, as well as development of imposed health-hazard control regulation for local community.« less
ScienceCast 121: The Effects of Space Weather on Aviation
2013-10-25
Ordinary air travelers can be exposed to significant doses of radiation during solar storms. A new computer model developed by NASA aims to help protect the public by predicting space weather hazards to aviation.
78 FR 64049 - Information Collection Activities
Federal Register 2010, 2011, 2012, 2013, 2014
2013-10-25
... radioactive material being transported; external radiation levels do not exceed prescribed limits; and... radioactive materials in commerce. Annual Reporting and Recordkeeping Burden: Number of Respondents: 3,817... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket No...
Detection and location of metal fragments in the human body
NASA Technical Reports Server (NTRS)
Brown, R. L.; Neuschaefer, R. W.
1970-01-01
Portable electronic device, based on the design of an eddy current gage, detects ferrous and nonferrous metal fragments. Device is more easily transported than X-ray equipment and does not present a radiation hazard.
NASA Technical Reports Server (NTRS)
Buecker, H.
1992-01-01
The Biostack experiments address especially the biological effects of the galactic particles of high atomic number and high energy, called HZE particles. The objective of the experiments is to substantiate the assessment of spaceflight radiation hazards especially regarding these particles.
Bross, I D; Driscoll, D L
1981-01-01
An official report on the health hazards to nuclear submarine workers at the Portsmouth Naval Shipyard (PNS), who were exposed to low-level ionizing radiation, was based on a casual inspection of the data and not on statistical analyses of the dosage-response relationships. When these analyses are done, serious hazards from lung cancer and other causes of death are shown. As a result of the recent studies on nuclear workers, the new risk estimates have been found to be much higher than the official estimates currently used in setting NRC permissible levels. The official BEIR estimates are about one lung cancer death per year per million persons per rem[s]. The PNS data show 189 lung cancer deaths per year per million persons per rem.
76 FR 35130 - Pipeline Safety: Control Room Management/Human Factors
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-16
... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration 49 CFR Parts...: Control Room Management/Human Factors AGENCY: Pipeline and Hazardous Materials Safety Administration... safety standards, risk assessments, and safety policies for natural gas pipelines and for hazardous...
Adjuvant Radiation Therapy Treatment Time Impacts Overall Survival in Gastric Cancer
DOE Office of Scientific and Technical Information (OSTI.GOV)
McMillan, Matthew T.; Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania; Ojerholm, Eric
Purpose: Prolonged radiation therapy treatment time (RTT) is associated with worse survival in several tumor types. This study investigated whether delays during adjuvant radiation therapy impact overall survival (OS) in gastric cancer. Methods and Materials: The National Cancer Data Base was queried for patients with resected gastric cancer who received adjuvant radiation therapy with National Comprehensive Cancer Network–recommended doses (45 or 50.4 Gy) between 1998 and 2006. RTT was classified as standard (45 Gy: 33-36 days, 50.4 Gy: 38-41 days) or prolonged (45 Gy: >36 days, 50.4 Gy: >41 days). Cox proportional hazards models evaluated the association between the following factors and OS: RTT, interval from surgery to radiationmore » therapy initiation, interval from surgery to radiation therapy completion, radiation therapy dose, demographic/pathologic and operative factors, and other elements of adjuvant multimodality therapy. Results: Of 1591 patients, RTT was delayed in 732 (46%). Factors associated with prolonged RTT were non-private health insurance (OR 1.3, P=.005) and treatment at non-academic facilities (OR 1.2, P=.045). Median OS and 5-year actuarial survival were significantly worse in patients with prolonged RTT compared with standard RTT (36 vs 51 months, P=.001; 39 vs 47%, P=.005); OS worsened with each cumulative week of delay (P<.0004). On multivariable analysis, prolonged RTT was associated with inferior OS (hazard ratio 1.2, P=.002); the intervals from surgery to radiation therapy initiation or completion were not. Prolonged RTT was particularly detrimental in patients with node positivity, inadequate nodal staging (<15 nodes examined), and those undergoing a cycle of chemotherapy before chemoradiation therapy. Conclusions: Delays during adjuvant radiation therapy appear to negatively impact survival in gastric cancer. Efforts to minimize cumulative interruptions to <7 days should be considered.« less
NASA Astrophysics Data System (ADS)
Hultquist, C.; Cervone, G.
2015-12-01
Citizen-led movements producing scientific environmental information are increasingly common during hazards. After the Japanese earthquake-triggered tsunami in 2011, the government produced airborne remote sensing data of the radiation levels after the Fukushima nuclear reactor failures. Advances in technology enabled citizens to monitor radiation by innovative mobile devices built from components bought on the Internet. The citizen-led Safecast project measured on-ground levels of radiation in the Fukushima prefecture which total 14 million entries to date in Japan. This non-authoritative citizen science collection recorded radiation levels at specific coordinates and times is available online, yet the reliability and validity of the data had not been assessed. The nuclear incident provided a case for assessment with comparable dimensions of citizen science and authoritative data. To perform a comparison of the datasets, standardization was required. The sensors were calibrated scientifically but collected using different units of measure. Radiation decays over time so temporal interpolation was necessary for comparison of measurements as being the same time frame. Finally, the GPS located points were selected within the overlapping spatial extent of 500 meters. This study spatially analyzes and statistically compares citizen-volunteered and government-generated radiation data. Quantitative measures are used to assess the similarity and difference in the datasets. Radiation measurements from the same geographic extents show similar spatial variations which suggests that citizen science data can be comparable with government-generated measurements. Validation of Safecast demonstrates that we can infer scientific data from unstructured and not vested data. Citizen science can provide real-time data for situational awareness which is crucial for decision making during disasters. This project provides a methodology for comparing datasets of radiological measurements over time and space. Integrating data for assessment from different earth sensing systems is an essential step to address the big data challenges of volume, velocity, variety, and veracity.
Situational awareness of hazards: Validation of multi-source radiation measurements
NASA Astrophysics Data System (ADS)
Hultquist, C.; Cervone, G.
2016-12-01
Citizen-led movements producing scientific hazard data during disasters are increasingly common. After the Japanese earthquake-triggered tsunami in 2011, and the resulting radioactive releases at the damaged Fukushima Daiichi nuclear power plants, citizens monitored on-ground levels of radiation with innovative mobile devices built from off-the-shelf components. To date, the citizen-led SAFECAST project has recorded 50 million radiation measurements worldwide, with the majority of these measurements from Japan. The analysis of data which are multi-dimensional, not vetted, and provided from multiple devices presents big data challenges due to their volume, velocity, variety, and veracity. While the SAFECAST project produced massive open-source radiation measurements at specific coordinates and times, the reliability and validity of the overall data have not yet been assessed. The nuclear disaster provides a case for assessing the SAFECAST data with official aerial remote sensing radiation data jointly collected by the governments of the United States and Japan. A spatial and statistical assessment of SAFECAST requires several preprocessing steps. First, SAFECAST ionized radiation sensors collected data using different units of measure than the government data, and they had to be converted. Secondly, the normally occurring radiation and decay rates of Cesium from deposition surveys were used to properly compare measurements in space and time. Finally, the GPS located points were selected within overlapping extents at multiple spatial resolutions. Quantitative measures were used to assess the similarity and differences in the observed measurements. Radiation measurements from the same geographic extents show similar spatial variations and statistically significant correlations. The results suggest that actionable scientific data for disasters and emergencies can be inferred from non-traditional and not vetted data generated through citizen science projects. This project provides a methodology for comparing datasets of radiological measurements over time and space. Integrating data for assessment from different Earth sensing systems is paramount for societal and environmental problems.