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Sample records for radioimmunological hpl determination

  1. A simplified radioimmunological method for the determination of human beta-endorphin in cerebrospinal fluid.

    PubMed

    Przuntek, H; Stasch, J P; Graf, M; Pflughaupt, K W; Gropp, N; Witteler, M

    1981-01-01

    Human beta-endorphin-like immunoreactive substances (beta h-EI) in human cerebrospinal fluid (CSF) were determined radioimmunologically. The cross reactivity of the antibodies to human beta-endorphin (beta h-E) amounted to 40% for human beta-lipotropin (beta h-LPH) whilst it was less than 1% for leu- and metenkephalin, alpha- and gamma-endorphin, fraction I and II [5], substance P and alpha-MSH. Prior to radioimmunological determination, an adsorbtion of beta h-EI from CSF with silicic acid was carried out and followed by a desorbtion, using a mixture of aceton/hydrochloric acid. This method was chosen because of the ratio of beta h-LPH to beta h-E in the desorbate can be shifted in favour of beta h-E owing to the variation in recoveries r (r beta h-LPH = 33%, r beta h-E = 64%). On the one hand, this enables a more specific determination of beta h-E and, on the other hand, and separation of any peptidase than may be present [9]. An adsorbtion/desorbtion of 2 ml CSF surfaces to prove the presence of 20-150 pg/ml (65-48 fmol/ml) of beta h-EI. The CSF of 28 patients with various neurological diseases was examined and 24 of them had concentrations of 20-70 pg/ml beta h-EI. The remaining four which had concentrations less than 20 pg/ml, came from meningitis patients undergoing corticoid therapy. A purchasable RIA kid was tested for its determination of beta h-E and was found to be unsuitable.

  2. Radioimmunological determination of insulinlike growth factors I and II in normal subjects and in patients with growth disorders and extrapancreatic tumor hypoglycemia.

    PubMed Central

    Zapf, J; Walter, H; Froesch, E R

    1981-01-01

    Serum levels of immunoreactive insulinlike growth factors (IGF) I and II were determined by a modified IGF I and a new IGF II radioimmunoassay in normal children and adults, and in patients with acromegaly, isolated growth hormone deficiency, and extrapancreatic tumor hypoglycemia. Serum samples were gel filtered by a simple routine procedure at acidic pH to dissociate and separate IGF from the IGF carrier protein. Mean immunoreactive IGF I levels (+/- SD; corrected for crossreactivity of IGF II) were 193 +/- 58 ng/ml in normal adult subjects, 712 +/- 245 ng/ml in acromegalic patients and 24 +/- 14 ng/ml in patients with isolated growth hormone deficiency. The lack of growth hormone alone, irrespective of an otherwise normal hormonal status, appears to be responsible for the drastic decrease of IGF I levels. Oversecretion of growth hormone does not increase the levels of immunoreactive IGF II: mean levels (+/- SD; corrected for crossreactivity of IGF I) in normal and acromegalic subjects are virtually identical (647 +/- 126 and 641 +/- 189 ng/ml, respectively). Apparently, normal growth hormone levels stimulate IGF II production already maximally. However in growth hormone deficiency immunoreactive IGF II is significantly decreased (252 +/- 99 ng/ml). Thus, IGF II, like IGF I, is growth hormone dependent. But in contrast to IGF I, the growth hormone dependence of IGF II seems to become apparent only at subnormal growth hormone levels. In normal children IGF I is age dependent: it is low in newborn cord sera (51 +/- 20 ng/ml) and gradually rises into the adult range with increasing age. At the onset of and during puberty mean IGF I levels lie above prepubertal values. In contrast, IGF II levels in normal children are independent of age and pubertal stage beyond the first year of life, whereas newborns have significantly lower IGF II values. Hypoglycemia resulting from extrapancreatic tumors is not associated with increased immunoreactive IGF I or II levels. IGF I is

  3. Defining heterochromatin in C. elegans through genome-wide analysis of the heterochromatin protein 1 homolog HPL-2.

    PubMed

    Garrigues, Jacob M; Sidoli, Simone; Garcia, Benjamin A; Strome, Susan

    2015-01-01

    Formation of heterochromatin serves a critical role in organizing the genome and regulating gene expression. In most organisms, heterochromatin flanks centromeres and telomeres. To identify heterochromatic regions in the heavily studied model C. elegans, which possesses holocentric chromosomes with dispersed centromeres, we analyzed the genome-wide distribution of the heterochromatin protein 1 (HP1) ortholog HPL-2 and compared its distribution to other features commonly associated with heterochromatin. HPL-2 binding highly correlates with histone H3 mono- and dimethylated at lysine 9 (H3K9me1 and H3K9me2) and forms broad domains on autosomal arms. Although HPL-2, like other HP1 orthologs, binds H3K9me peptides in vitro, the distribution of HPL-2 in vivo appears relatively normal in mutant embryos that lack H3K9me, demonstrating that the chromosomal distribution of HPL-2 can be achieved in an H3K9me-independent manner. Consistent with HPL-2 serving roles independent of H3K9me, hpl-2 mutant worms display more severe defects than mutant worms lacking H3K9me. HPL-2 binding is enriched for repetitive sequences, and on chromosome arms is anticorrelated with centromeres. At the genic level, HPL-2 preferentially associates with well-expressed genes, and loss of HPL-2 results in up-regulation of some binding targets and down-regulation of others. Our work defines heterochromatin in an important model organism and uncovers both shared and distinctive properties of heterochromatin relative to other systems.

  4. Insect herbivores selectively suppress the HPL branch of the oxylipin pathway in host plants.

    PubMed

    Savchenko, Tatyana; Pearse, Ian S; Ignatia, Laura; Karban, Richard; Dehesh, Katayoon

    2013-02-01

    Insect herbivores have developed a myriad of strategies to manipulate the defense responses of their host plants. Here we provide evidence that chewing insects differentially alter the oxylipin profiles produced by the two main and competing branches of the plant defensive response pathway, the allene oxide synthase (AOS) and hydroperoxide lyase (HPL) branches, which are responsible for wound-inducible production of jasmonates (JAs), and green leafy volatiles (GLVs) respectively. Specifically, we used three Arabidopsis genotypes that were damaged by mechanical wounding or by insects of various feeding guilds (piercing aphids, generalist chewing caterpillars and specialist chewing caterpillars). We established that emission of GLVs is stimulated by wounding incurred mechanically or by aphids, but release of these volatiles is constitutively impaired by both generalist and specialist chewing insects. Simultaneously, however, these chewing herbivores stimulated JA production, demonstrating targeted insect suppression of the HPL branch of the oxylipin pathway. Use of lines engineered to express HPL constitutively, in conjunction with quantitative RT-PCR-based expression analyses, established a combination of transcriptional and post-transcriptional reprogramming of the HPL pathway genes as the mechanistic basis of insect-mediated suppression of the corresponding metabolites. Feeding studies suggested a potential evolutionary advantage of suppressing GLV production, as caterpillars preferably consumed leaf tissue from plants that had not been primed by these volatile cues.

  5. Varietal Dependence of GLVs Accumulation and LOX-HPL Pathway Gene Expression in Four Vitis vinifera Wine Grapes

    PubMed Central

    Qian, Xu; Xu, Xiao-Qing; Yu, Ke-Ji; Zhu, Bao-Qing; Lan, Yi-Bin; Duan, Chang-Qing; Pan, Qiu-Hong

    2016-01-01

    Variety is one of the major factors influencing grape and wine aromatic characteristics. Green leaf volatiles (GLVs), derived from lipoxygenase-hydroperoxides lyase (LOX-HPL) pathway, are important components for the aromatic quality of grapes and wines. However, the varietal difference regarding GLVs accumulation and related gene expression are poorly studied. This work exhibited that the accumulation of various GLVs and the expression of LOX-HPL pathway genes in four Vitis vinifera wine grape cultivars: Syrah, Muscat Tchervine, Gewürztraminer and Chardonnay. The results showed a variety dependence of GLVs profile. Muscat Tchervine harvested grapes contained less C6 aldehydes and the most abundant esters, which corresponded to very low VvLOXA and VvHPL1 expression abundance as well as high VvAAT transcript in this variety. High expression level of both VvLOXA and VvHPL1 paralleled with higher level of C6 aldehydes together with higher alcohols in Syrah grape. Gewürztraminer and Chardonnay grapes had high aldehydes and alcohols as well as low esters, which were resulted from their higher expression level of VvLOXA or VvHPL1 and lower VvAAT. From these above corresponding relations, it is concluded that VvLOXA, VvHPL1 and VvAAT in the LOX-HPL pathway are targets for altering GLVs composition in the grape varieties. PMID:27886056

  6. Isolation and characterization of two hydroperoxide lyase genes from grape berries : HPL isogenes in Vitis vinifera grapes.

    PubMed

    Zhu, Bao-Qing; Xu, Xiao-Qing; Wu, Yu-Wen; Duan, Chang-Qing; Pan, Qiu-Hong

    2012-07-01

    C6 compounds are the major fraction of the volatile profiles of grape berries, contributing the typical 'green' aroma to the grape and wine. Hydroperoxide lyase (HPL) catalyzes the cleavage of fatty acid hydroperoxides to produce C6 compounds. Two hypothetical genes, VvHPL1 and VvHPL2 were cloned from grape berries (Vitis vinifera L. Cabernet Sauvignon). Bioinformatics analysis revealed that the proteins encoded by these two genes both belong to subfamily of cytochrome P450 and contain typical conserved domains of HPLs, and have high identity with HPLs from other plants. Prokaryotically-expressed VvHPL1 and VvHPL2 with thioredoxin-6xHis-fusion partner were confirmed to have enzymatic activity. VvHPL1 is specific for 13-HPOD (T) producing C6 aldehydes with relatively higher activity and VvHPL2 catalyzes the cleavage of both 9- and 13-hydroperoxides producing C6 aldehydes and C9 aldehydes respectively. Analysis of real time-PCR showed that VvHPL2 was highly expressed in the leaves and the flowers of the grapes, while relatively low transcript abundance was detected in the berries, tendril and stems; VvHPL1 had high expression in all detected tissues. During grape berry development, the expression of these two isogenes presented similar trends with a rapid increase after veraison and a decrease at full-ripen stage, which roughly corresponded to the accumulation of their volatile products. These data lay an essential foundation for further study on the accumulation and control of C6 volatiles in grape berries.

  7. Radioimmunological screening and gas chromatographic determination of morphine and related narcotic analgesics in post mortem blood.

    PubMed

    Cimbura, G; Koves, E

    1981-01-01

    A sensitive, reproducible, and relatively specific procedure is presented for the screening, identification, and quantitation of morphine, hydromorphone, codeine, oxycodone, and hydrocodone in autopsy blood. The drugs are isolated from whole blood by adsorption on an XAD-2 resin slurry and subsequent elution with an organic solvent mixture. Part of the resin extract is screened for morphine and related cross-reacting compounds by a commercially available radioimmunoassay (RIA) and the remainder of the same extract is analyzed by gas chromatography using a nitrogen/phosphorus detector (GC/NP). The procedure has been used frequently in forensic toxicological casework. Since toxic blood concentrations of hydrocodone have not been well documented, the results of toxicological examination of two fatalities involving this drug are presented.

  8. [The diagnostic value of the radioimmunological estimation of prostatic acid phosphatase. Comparative value of the measurement of enzyme activity (author's transl)].

    PubMed

    Tellier, J L; Chatal, J F; Bourdin, S; Auvigne, J; Etienne, P; Faye, R

    1981-01-01

    Radioimmunological estimation of prostatic acid phosphatase was carried out in 72 reference subjects, 46 patients with benign prostatic hypertrophy, 106 patients with untreated prostatic carcinoma and 25 patients with a carcinoma of some other origin. The mean concentration in non-acidified serum was 1.3 +/- 0.4 (M +/- SD) ng/ml for the reference group and 1.6 +/- 0.8 ng/ml for the benign hypertrophy group. The upper limit of discriminatory values for the diagnosis of prostatic carcinoma was fixed at 3 ng/ml. Taking this value, the overall percentage of positive results for carcinoma of the prostate was 61% (65/106). The number of cases with a value greater than 3 ng/ml was 3/18 (17%) for stage A, 8/27 (30%) for stage B, 7/13 (54%) for stage C and 47/48 (98%) for stage D. 8% (2/25) of carcinomas of another origin gave a positive result. The results of estimation using the radioimmunological technique were compared with those obtained by the measurement of enzyme activity using para nitro-phenyl phosphate as a substrate in 34 untreated prostatic carcinomas (all stages mixed together). When measurements by both techniques were carried out under the same ideal conditions using fresh sera as soon as possible after the blood was drawn, the result was abnormal in 10 cases out of 12 (83%) for the radioimmunological method and in 8 cases out of 12 (67%) for the measurement of enzyme activity. By contrast, under routine conditions, the positive percentage figures were 77% (17/22) for the radioimmunological technique and only 36% (8/22) for the measurement of enzyme activity. It would thus appear that radioimmunological measurement is more reliable than the measurement of enzyme activity.

  9. CHRONICLE: Twelfth International Symposium on Gas and Chemical Lasers and High-Power Laser Conference (GCL/HPL '98)

    NASA Astrophysics Data System (ADS)

    Boreysho, A. S.; Koretskii, Ya P.; Mashendzhinov, Viktor I.; Morozov, A. V.; Rotinyan, Mikhail A.

    1999-03-01

    A review is given of the papers presented at the GCL/HPL'98 Meeting held on August 31 — September 5, 1998 in St Petersburg. A brief account is given of the associated exhibition and a satellite conference held at the All-Russia Scientific-Research Institute of Experimental Physics (Russian Federal Nuclear Centre) in the city of Sarov.

  10. Direct mitochondrial dysfunction precedes reactive oxygen species production in amiodarone-induced toxicity in human peripheral lung epithelial HPL1A cells

    SciTech Connect

    Nicolescu, Adrian C. Ji, Yanbin; Comeau, Jeannette L.; Hill, Bruce C.; Takahashi, Takashi; Brien, James F.; Racz, William J.; Massey, Thomas E.

    2008-03-15

    Amiodarone (AM), a drug used in the treatment of cardiac dysrrhythmias, can produce severe pulmonary adverse effects, including fibrosis. Although the pathogenesis of AM-induced pulmonary toxicity (AIPT) is not clearly understood, several hypotheses have been advanced, including increased inflammatory mediator release, mitochondrial dysfunction, and free-radical formation. The hypothesis that AM induces formation of reactive oxygen species (ROS) was tested in an in vitro model relevant for AIPT. Human peripheral lung epithelial HPL1A cells, as surrogates for target cells in AIPT, were susceptible to the toxicity of AM and N-desethylamiodarone (DEA), a major AM metabolite. Longer incubations ({>=} 6 h) of HPL1A cells with 100 {mu}M AM significantly increased ROS formation. In contrast, shorter incubations (2 h) of HPL1A cells with AM resulted in mitochondrial dysfunction and cytoplasmic cytochrome c translocation. Preexposure of HPL1A cells to ubiquinone and {alpha}-tocopherol was more effective than that with Trolox C (registered) or 5,5-dimethylpyrolidine N-oxide (DMPO) at preventing AM cytotoxicity. These data suggest that mitochondrial dysfunction, rather than ROS overproduction, represents an early event in AM-induced toxicity in peripheral lung epithelial cells that may be relevant for triggering AIPT, and antioxidants that target mitochondria may potentially have beneficial effects in AIPT.

  11. Understanding the Impact of a Global Universal Design for Learning (UDL) Virtual Classroom on Jamaican Educators through the Lens of How People Learn (HPL)

    ERIC Educational Resources Information Center

    Best, Kathryn Whitaker

    2016-01-01

    This case study examined learning components and outcomes of the UDL Virtual Classroom project, a web-based professional development program that was a collaboration between educators in the United States and Jamaica. The study applied the HPL lens (NRC, 2000) in order to understand the ways that Jamaican educator-participants perceived the…

  12. Preparation of pooled human platelet lysate (pHPL) as an efficient supplement for animal serum-free human stem cell cultures.

    PubMed

    Schallmoser, Katharina; Strunk, Dirk

    2009-10-30

    Platelet derived growth factors have been shown to stimulate cell proliferation efficiently in vivo(1,2) and in vitro. This effect has been reported for mesenchymal stromal cells (MSCs), fibroblasts and endothelial colony-forming cells with platelets activated by thrombin(3-5) or lysed by freeze/thaw cycles(6-14) before the platelet releasate is added to the cell culture medium. The trophic effect of platelet derived growth factors has already been tested in several trials for tissue engineering and regenerative therapy.(1,15-17) Varying efficiency is considered to be at least in part due to individually divergent concentrations of growth factors(18,19) and a current lack of standardized protocols for platelet preparation.(15,16) This protocol presents a practicable procedure to generate a pool of human platelet lysate (pHPL) derived from routinely produced platelet rich plasma (PRP) of forty to fifty single blood donations. By several freeze/thaw cycles the platelet membranes are damaged and growth factors are efficiently released into the plasma. Finally, the platelet fragments are removed by centrifugation to avoid extensive aggregate formation and deplete potential antigens. The implementation of pHPL into standard culture protocols represents a promising tool for further development of cell therapeutics propagated in an animal protein-free system.

  13. Interconversion of ketoprofen recognition in firefly luciferase-catalyzed enantioselective thioesterification reaction using from Pylocoeria miyako (PmL) and Hotaria parvura (HpL) just by mutating two amino acid residues.

    PubMed

    Kato, Dai-ichiro; Hiraishi, Yoshihiro; Maenaka, Mika; Yokoyama, Keisuke; Niwa, Kazuki; Ohmiya, Yoshihiro; Takeo, Masahiro; Negoro, Seiji

    2013-11-01

    We identified the critical amino acid residues for substrate recognition using two firefly luciferases from Pylocoeria miyako (PmL) and Hotaria parvura (HpL), as these two luciferase enzymes exhibit different activities toward ketoprofen. Specifically, PmL can catalyze the apparent enantioselective thioesterification reaction, while HpL cannot. By comparing the amino acid sequences around the active site, we identified two residues (I350 and M397 in PmL and F351 and S398 in HpL) that were different between the two enzymes, and the replacement of these amino acids resulted in changing the ketoprofen recognition pattern. The inactive HpL was converted to the active enzyme toward ketoprofen and vice versa for PmL. These residues also affected the enantioselectivity toward ketoprofen; however, the bioluminescent color was not affected. In addition, using molecular dynamics calculations, the replacement of these two amino acids induced changes in the state of hydrogen bonding between ketoprofen and the S349 side chain through the active site water. As S349 is not considered to influence color tuning, these changes specifically caused the differences in ketoprofen recognition in the enzyme.

  14. Radioimmunoassay and chemical ionization/mass spectrometry compared for plasma cortisol determination

    SciTech Connect

    Lindberg, C.; Johnson, S.; Hedner, P.; Gustafsson, A.

    1982-01-01

    A method is described for determination of cortisol in plasma and urine, based on chemical ionization/mass spectrometry with deuterium-labeled cortisol as the internal standard. The within-run precision (CV) was 2.5-5.7%, the between-run precision 4.6%. Results by this method were compared with those by a radioimmunological method (RIANEN Cortisol, New England Nuclear) for 395 plasma samples. The latter method gave significantly higher (approx. 25%) cortisol values.

  15. Development and validation of a stability-indicating RP-HPL C-CAD method for gabapentin and its related impurities in presence of degradation products.

    PubMed

    Ragham, Pramod Kumar; Chandrasekhar, Kothapalli B

    2016-06-05

    The objective of the current study was to develop and validate a sensitive and specific LC-MS compatible stability indicating reversed phase liquid chromatographic method for the quantitative determination of Gabapentin and its related substances using Corona charged aerosol detection (CAD). The chromatographic conditions were optimized using a Kinetix Biphenyl column with gradient elution using a mobile phase composed of pH 4.2 ammonium acetate, acetonitrile, and methanol. Forced degradation was observed in basic and peroxide conditions and the major degradants were identified by LC-MS/MS analysis. The developed RP-HPLC CAD method was validated according to ICH guidelines. The LOD and LOQ values for Gabapentin and all its related impurities ranged from 0.075μg/mL to 0.18μg/mL and 0.25μg/mL to 0.60μg/mL, respectively. The recovery for all impurities ranged from 91.0 to 105.6%w/w. Solutions were stable for 7days at room temperature. The validated method produced acceptable precision, linearity, accuracy, robustness and ruggedness.

  16. [Analysis of digoxin by a radio-immunologic].

    PubMed

    Scherrmann, J M; Bourdon, R

    1976-01-01

    A more accurate knowledge of the effects of cardiotonic heterosides can be gained using radiocompetition. The present investigation aimed at: -comparing two commercial kits, the usual quality criteria being applied; -estimating cross-reaction between the immune systems and the endogenous as well as exogenous structural analogues; -establishing the therapeutical or toxic levels in man.

  17. Unified mass-action theory for virus neutralization and radioimmunology.

    PubMed

    Trautman, R

    1976-01-01

    All ideas implicit in the papers since 1953 involved in applying mass-action thermodynamics to antibody-antigen reactions are unified by the use of: (a) the intermediary concept of extent of reaction; (b) the concept of intrinsic association constant; (c) a statistical analysis for probable complexes; and (d) identification of the complex or complexes that contribute to the bioassay. Several general theoretical examples are given that show the limitations of linear interpretations of equilibrium data. Two practical examples from the literature illustrate foot-and-mouth disease virus and influenza virus neutralization.

  18. [Plasma hormone concentrations in induced abortion with local prostaglandin administration in the 1st trimester].

    PubMed

    Rath, W; König, A; Ulbrich, R; Hilgers, R; Kuske, R; Kuhn, W

    1983-01-01

    Abortion was performed by curettage on 71 women with pregnancies between the 7th and the 13th week of gestation seven to eight hours after intracervical application of a tylose gel containing 3mg prostaglandin F2 alpha. Prior to the application of the prostaglandin and immediately before the surgical intervention a sonographic examination for determining the vitality of the pregnancy was carried out.--Plasma progesteron, estradiol and HPL levels were determined radioimmunologically prior to the application of prostaglandin, at four-hour intervals on the day of intervention, and 24, 48 and 72 hours after the intervention. In 22 women a complete or an incomplete abortion occurred; in two cases a blighted ovum was observed; 47 pregnancies, according to sonographic examination, remained intact until curettage. After seven to eight hours duration of the effect of the prostaglandin gel, progesterone levels were found to be reduced to 60.5 per cent and 17-beta-estradiol to 31.4 per cent of the initial values, whereas the HPL values fell below the specificity of the testing procedure (12.5 ng/ml). Comparative investigations of the pregnancies which, according to sonographic findings, remained intact until curettage and those which were aborted after the application of prostaglandin did not, in spite of low plasma progesterone and estradiol levels in the abortive group, reveal any statistically significant differences. The abortive effect--even with local application--of the prostaglandins was confirmed. Conclusions regarding the effective mechanism of the prostaglandins upon the fetoplacental unit and the function of the corpus luteum remain subject to speculation.

  19. Coding potential of transfected human placental lactogen genes.

    PubMed Central

    Reséndez-Pérez, D; Ramírez-Solís, R; Varela-Echavarría, A; Martínez-Rodríguez, H G; Barrera-Saldaña, H A

    1990-01-01

    We have joined the promoter-less sequences of the three hPL genes (hPL-1, hPL-3 and hPL-4) to strong transcriptional control elements. in vivo 35S-labeled proteins from the culture medium of cells transfected with the genes were resolved on SDS-polyacrylamide gels. The presence of characteristic labeled bands, visualized by autoradiography, determined that hPL-4 and hPL-3, but not hPL-1, contribute to the production of mature hPL. In these experiments hPL-3 expressed more RNA and protein than hPL-4. By exchanging the first two exons among hPL and hGH genes, we determined that the abundance of chimeric proteins depended on the genetic origin of the first two exons. Finally, we found evidence indicating that the splice mutation (G----A) at the beginning of the second intron of hPL-1, is not the only cause of the apparent lack of inactivity of this gene, since its reversion does not restore expression. Images PMID:2395633

  20. [Dose-dependent effect of locally administered sulprostone gel on serum luteal and placental hormones in cervix priming in the 1st trimester].

    PubMed

    Rath, W; Pitzel, L; Hilgers, R; Kuhn, W

    1989-01-01

    In a prospective, randomised study 30 primigravidae were treated with 25 micrograms, 50 mu, or 100 micrograms sulprostone gel in order to soften the cervix prior to first trimester termination of pregnancy. 10 multigravidae received only the gel vehicle tylose. For objective demonstration of the priming effect, the force required for dilatation of the cervical canal was measured in Newton by a special tonometer before prostaglandin (PG) application and before operation. Serum progesterone, 17-beta-estradiol and hP1 levels were determined radioimmunologically prior to PG application and at two-hours intervals until curettage. A sonographic examination for determing the vitality of the pregnancy was performed before PG administration and immediately before the surgical intervention. There were no significant differences in the primig effect between the 50 micrograms and 100 micrograms sulprostone-treated group; the application of 25 micrograms sulprostone was significantly less effective. After 100 micrograms sulprostone gel abortion occurred in 2 patients, 6 women showed a marked decrease in hPl concentrations, progesterone levels were found to be reduced to 31.6-78.7% and 17-beta-estradiol to 10-40% of the initial values before PG application. We found a close time correlation between the occurrence of contraction-induced lower abdominal pain and the fall in hormone concentrations. No abortions occurred in any of the patients treated with 50 micrograms sulprostone gel; in 9 women without clinical symptoms no significant changes of the hormone concentrations were observed. In contrast to the previously published literature our results indicate that effective cervical ripening can be achieved by this method without disturbance of the feto-placental unit and the trophoblast respectively.

  1. Test Report of Improved Backhoe

    DTIC Science & Technology

    2003-07-01

    HPL 750 S- 3 FAUN F 1110 HPL 1100 S 4 FAUN F 1110 IL HPL 750 S 4 FAUN F 1310 HPL 1500 S 5 FAUN F 1410 HPL 2000 S 6 FAUN F 1810 HPL 2500 S 7... FAUN F 2000 C HPL 2500 S 8 FAUN F 2010 HPL 2500 S 8 FAUN F 3500 HXI 3600 10 FAUN F 5000 XXXXXXXX 10 FIATALLIS 215 HPL 600 S 2 FIATALLIS 545-B HPL

  2. Relationship between shoulder roll and hand propulsion in the front crawl stroke.

    PubMed

    Kudo, Shigetada; Sakurai, Yoshihisa; Miwa, Takahiro; Matsuda, Yuji

    2017-05-01

    This study re-evaluated the magnitude of hand propulsion (HP) in the pull and push phases of the front crawl stroke and investigated the association between the angular velocity of shoulder roll (ωSR) and hand propulsive lift (HPL). ωSR was computed in the plane normal to a forward direction for 16 skilled swimmers performing the front crawl stroke at a maximal sprinting pace. HP, hand propulsive drag (HPD) and HPL were determined by a dynamic pressure approach. HP and HPD in the pull phase were greater than in the push phase (P < 0.05) while HPL in the pull phase was similar to that in the push phase. Eleven swimmers out of the 16 swimmers had a significant within-swimmers correlation between ωSR and HPL in the push phase (P < 0.05). That is, HPL increased in the push phase as the ωSR of rolling back to the neutral position became faster. A swimmer should use more drag for hand propulsion in the pull phase and propulsion from drag and lift equally in the push phase. Based on the relationship between ωSR and HPL in the push phase, a possible stroke technique to enhance HPL using ωSR is discussed.

  3. Stochastic determination of matrix determinants.

    PubMed

    Dorn, Sebastian; Ensslin, Torsten A

    2015-07-01

    Matrix determinants play an important role in data analysis, in particular when Gaussian processes are involved. Due to currently exploding data volumes, linear operations-matrices-acting on the data are often not accessible directly but are only represented indirectly in form of a computer routine. Such a routine implements the transformation a data vector undergoes under matrix multiplication. While efficient probing routines to estimate a matrix's diagonal or trace, based solely on such computationally affordable matrix-vector multiplications, are well known and frequently used in signal inference, there is no stochastic estimate for its determinant. We introduce a probing method for the logarithm of a determinant of a linear operator. Our method rests upon a reformulation of the log-determinant by an integral representation and the transformation of the involved terms into stochastic expressions. This stochastic determinant determination enables large-size applications in Bayesian inference, in particular evidence calculations, model comparison, and posterior determination.

  4. Virulence Determination

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This chapter reviews the in vitro and in vivo assays that are available for determination of pathogenic potential of Listeria monocytogenes bacteria, highlighting the value of using multiplex PCR for rapid and accurate assessment of listerial virulence....

  5. Vitamin D reduces the inflammatory response by Porphyromonas gingivalis infection by modulating human β-defensin-3 in human gingival epithelium and periodontal ligament cells.

    PubMed

    De Filippis, Anna; Fiorentino, Margherita; Guida, Luigi; Annunziata, Marco; Nastri, Livia; Rizzo, Antonietta

    2017-04-03

    Periodontitis is a multifactorial polymicrobial infection characterized by a destructive inflammatory process. Porphyromonas gingivalis, a Gram-negative black-pigmented anaerobe, is a major pathogen in the initiation and progression of periodontitis; it produces several virulence factors that stimulate human gingival epithelium (HGE) cells and human periodontal ligament (HPL) cells to produce various inflammatory mediators. A variety of substances, such as vitamin D, have growth-inhibitory effects on some bacterial pathogens and have shown chemo-preventive and anti-inflammatory activity. We used a model with HGE and HPL cells infected with P. gingivalis to determine the influence of vitamin D on P. gingivalis growth and adhesion and the immunomodulatory effect on TNF-α, IL-8, IL-12 and human-β-defensin 3 production. Our results demonstrated, firstly, the lack of any cytotoxic effect on the HGE and HPL cells when treated with vitamin D; in addition, vitamin D inhibited P. gingivalis adhesion and infectivity in HGE and HPL cells. Our study then showed that vitamin D reduced TNF-α, IL-8, IL-12 production in P. gingivalis-infected HGE and HPL cells. In contrast, a significant upregulation of the human-β-defensin 3 expression in HGE and HPL cells induced by P. gingivalis was demonstrated. Our results indicate that vitamin D specifically enhances the production of the human-β-defensin 3 antimicrobial peptide and exerts an inhibitory effect on the pro-inflammatory cytokines, thus suggesting that vitamin D may offer possible therapeutic applications for periodontitis.

  6. [Determination of melamine residue in plant origin protein powders using high performance liquid chromatography-diode array detection and high performance liquid chromatography-electrospray ionization tandem mass spectrometry].

    PubMed

    Ding, Tao; Xu, Jinzhong; Li, Jianzhong; Shen, Chongyu; Wu, Bin; Chen, Huilan; Li, Shujuan

    2008-01-01

    A method for the determination of melamine residue in plant origin protein powders was developed using high performance liquid chromatography-diode array detection (HPLC-DAD) and HPLC-electrospray ionization tandem mass spectrometry (ESI-MS/MS). HPL-DAD was used in preliminary screening of the samples for melamine, and HPLC-MS/MS was used in the confirmatory of melamine. Trichloroacetic acid solution was used to precipitate proteins and to dissociate the target analyte from the sample matrix. The supernatant was cleaned up with strong cation exchange column for HPLC-MS/MS. The HPLC-DAD separation was carried out on a C18 column (250 mm x 4.6 mm, 5 microm) with 0.01 mol/L sodium n-heptanesulfate (pH adjusted to 4.5 with citric acid)-acetonitrile (90:10, v/v) as mobile phase at a flow rate of 1.0 mL/min, and detected at 240 nm. HPLC-MS/MS was performed in selected ion monitoring mode with trichloroacetic acid solution as ion pair reagent. The limits of detection were 10 mg/kg and 0.5 mg/kg for HPLC-DAD and HPLC-MS/MS, respectively. The mean recoveries were 76%-88% for HPLC-DAD and 72%-82% (matrix match calibration curve) for HPLC-MS/MS and the relative standard deviations were 3.4%-6.4% for both HPLC-DAD and HPLC-MS/MS.

  7. Immunocytochemical demonstration of chicken hypophyseal thyrotropes and development of a radioimmunological indicator for chicken TSH using monoclonal and polyclonal homologous antibodies in a subtractive strategy.

    PubMed

    Berghman, L R; Darras, V M; Chiasson, R B; Decuypere, E; Kühn, E R; Buyse, J; Vandesande, F

    1993-11-01

    The production and characterization of monoclonal antibodies (mAbs) toward the chicken pituitary glycoproteins are described. MAbs were first subdivided on an immunocytochemical (ICC) basis: one category of mAbs reacts with both thyrotropic and gonadotropic cells whereas another stains exclusively gonadotropic cells. The hypothesis that the former are anti-glycoprotein alpha and that the latter are anti-beta LH and/or anti-beta FSH mAbs was further elaborated in a homologous tracer binding assay. The putative anti-beta gonadotropin mAbs exclusively recognize iodinated USDA-cLH-I-1, whereas the supposed anti-alpha mAbs react with both USDA-cLH-I-1 and USDA-cFSH-I-1. The ICC localization of pituitary thyrotropes has been achieved in a double-staining protocol using an anti-LH mAb to subtract specifically the gonadotropic cells from the complete alpha-subunit-containing cell population. The result is a strictly cephalic cell population that is densely granulated in hyperthyroid and hardly detectable in hypothyroid birds. A similar subtractive approach was used to develop a thyroid-stimulating hormone (TSH)-indicator in RIA. The total titer of alpha-containing molecules is first quantified with an anti-alpha mAb. The contribution of both LH and FSH to this titer is then measured by homologous USDA-RIA and subtracted from the total alpha-immunoreactivity to give an indication of the TSH level of the sample. The direct effect of thyroid-releasing hormone on pituitary TSH release in vitro in juvenile chicks and the effect of hypo- and hyperthyroidism on circulating TSH levels in vivo in juvenile broilers have been demonstrated.

  8. Platelet lysate coating on scaffolds directly and indirectly enhances cell migration, improving bone and blood vessel formation.

    PubMed

    Leotot, Julie; Coquelin, Laura; Bodivit, Gwellaouen; Bierling, Philippe; Hernigou, Philippe; Rouard, Helene; Chevallier, Nathalie

    2013-05-01

    Suitable colonization and vascularization of tissue-engineered constructs after transplantation represent critical steps for the success of bone repair. Human platelet lysate (hPL) is composed of numerous growth factors known for their proliferative, differentiative and chemo-attractant effects on various cells involved in wound healing and bone growth. The aim of this study was to determine whether the delivery of human mesenchymal stromal cells (hMSC) seeded on hPL-coated hydroxyapatite/β-tricalcium phosphate (HA/β-TCP) scaffolds could enhance vascularization and bone formation, as well as to investigate the mechanisms by which hMSC participate in tissue regeneration. Our study demonstrates that hPL can be coated on HA/β-TCP scaffolds, which play direct and indirect effects on implanted and/or resident stem cells. Effectively, we show that hPL coating directly increases chemo-attraction to and adhesion of hMSC and endothelial cells on the scaffold. Moreover, we show that hPL coating induces hMSC to produce and secrete pro-angiogenic proteins (placental growth factor and vascular endothelial growth factor) which allow the proliferation and specific chemo-attraction of endothelial cells in vitro, thus improving in vivo neovascularization and new bone formation. This study highlights the potential of functionalizing biomaterials with hPL and shows that this growth factor combination can have synergistic effects leading to enhanced bone and blood vessel formation.

  9. [Changes in the 13,14-dihydro-15-ketoprostaglandin F2alpha and oxytocin level in the 1st trimester following beta-sympathomimetic and intracervical prostaglandin E2 gel administration].

    PubMed

    Osmers, R; Goeschen, K; Fuchs, A R; Dennemark, N

    1988-01-01

    3 ml tylose gel containing 500 micrograms PGE2 was injected into the cervical canal of 23 patients prior to first trimester abortion. 11 patients received 5 mg fenoterol orally before the PGE2-gel application and 12 patients a placebo tablet. The PGFM and oxytocin concentrations in plasma were determined radioimmunologically. The results showed the dominant role of elevated PGFM levels in the clinical prevalence of pain during induced abortion.

  10. Genomics of sex determination.

    PubMed

    Zhang, Jisen; Boualem, Adnane; Bendahmane, Abdelhafid; Ming, Ray

    2014-04-01

    Sex determination is a major switch in the evolutionary history of angiosperm, resulting 11% monoecious and dioecious species. The genomic sequences of papaya sex chromosomes unveiled the molecular basis of recombination suppression in the sex determination region, and candidate genes for sex determination. Identification and analyses of sex determination genes in cucurbits and maize demonstrated conservation of sex determination mechanism in one lineage and divergence between the two systems. Epigenetic control and hormonal influence of sex determination were elucidated in both plants and animals. Intensive investigation of potential sex determination genes in model species will improve our understanding of sex determination gene network. Such network will in turn accelerate the identification of sex determination genes in dioecious species with sex chromosomes, which are burdensome due to no recombination in sex determining regions. The sex determination genes in dioecious species are crucial for understanding the origin of dioecy and sex chromosomes, particularly in their early stage of evolution.

  11. Self-Determination.

    ERIC Educational Resources Information Center

    Transition Summary, 1988

    1988-01-01

    This issue of "Transition Summary" contains articles about self-determination and becoming a good self-advocate, with each article reflecting the experience of someone who has grown up with a disability. "The Many Facets of Self-Determination" (Michael Ward) discusses the concept of self-determination; offers an historical perspective of the…

  12. Rethinking the Category 'Determiner'

    ERIC Educational Resources Information Center

    Spangler, Wayne E.

    1975-01-01

    The 'determiner' category was originally set up by structuralists for identifying nouns. The rewrite rule for 'determiners' in transformational generative grammar is inadequate for showing correspondences between type and token. An appraisal of quantity terms might eliminate the concept of the 'determiner,' and replace that category with one of…

  13. Nephelometric determination of fluorine

    USGS Publications Warehouse

    Stevens, R.E.

    1936-01-01

    Fluorine in minerals may be determined with the nephelometer to about 1 per cent of the fluorine. The determination is made on an aliquot of the sodium chloride solution of the fluorine, obtained by the Berzelius method of extraction. The fluorine is precipitated as colloidal calcium fluoride in alcoholic solution, gelatin serving as a protective colloid. Arsenates, sulfates, and phosphates, which interfere with the determination, must be removed.

  14. Charge transfer complex of some nervous and brain drugs - Part 1: Synthesis, spectroscopic, analytical and biological studies on the reaction between haloperidol antipsychotic drugs with π-acceptors

    NASA Astrophysics Data System (ADS)

    El-Habeeb, Abeer A.; Al-Saif, Foziah A.; Refat, Moamen S.

    2013-02-01

    Donor-acceptor interactions between the electron donor haloperidol (HPL) and π-acceptors like 7,7,8,8-tetracyanoquinodimethane (TCNQ) and picric acid (PA) have been studied spectrophotometrically in CH3OH solvent. The donor-acceptor (charge transfer complexes) were discussed in terms of formation constant (KCT), molar extinction coefficient (ɛCT), standard free energy (ΔGo), oscillator strength (ƒ), transition dipole moment (μ), resonance energy (RN) and ionization potential (ID). The stoichiometry of these complexes was found to be 1:1 M ratio and having the formulas [(HPL)(TCNQ)] and [(HPL)(PA)], respectively. The charge transfer interaction was successfully applied to determine of HPL drug using mentioned common π-acceptors also, the results obtained herein are satisfactory for estimation of HPL compound in the pharmaceutical form. The formed solid charge-transfer complexes were also isolated and characterized using elemental analysis, conductivity, (infrared, Raman, and 1H NMR) spectra and X-ray powder diffraction (XRD). The experimental data of elemental analyses are in agreement with calculated data. The infrared spectra of both HPL complexes are confirming the participation of sbnd OH of 4-hydroxy-1-piperidyl moiety in the donor-acceptor chelation. The morphological surface of the resulted charge transfer complexes were investigated using scanning electron microscopy (SEM). The thermogravimetric analysis (TG/DTG) and differential scanning calorimetry (DSC) techniques were performed to give knowledge about the thermal stability behavior of the synthesized charge transfer complexes. Thermodynamic parameters were computed from the thermal decomposition data. These complexes were also tested for their antimicrobial activity against six different microorganisms, and the results were compared with the parent drug.

  15. The Association of Health-Promoting Lifestyle With Quality of Life Among the Iranian Elderly

    PubMed Central

    Rakhshani, Tayebeh; Shojaiezadeh, Davood; Lankarani, Kamran Bagheri; Rakhshani, Fatemeh; Kaveh, Mohammad Hossain; Zare, Najaf

    2014-01-01

    Background: As individuals live a longer life, health-promoting lifestyle (HPL) becomes even more essential, particularly with regard to maintaining functional independence and improving quality of life (QoL). Objectives: This study aimed to determine the association between QoL and HPL in the Iranian elderly living in Shiraz. Materials and Methods: This analytical cross-sectional study was conducted in 2013 at retirement centers of Shiraz City, Iran. The sample included 500 elderly who aged > 60 years. Proportional stratified random sampling was used to select the elderly from retirement centers. QoL was assessed by the Farsi version of Short Form Health Survey questionnaire (SF-36) and HPL was measured by health-promoting lifestyle profile (HPLP II). Data were analyzed using independent-samples t test, one-way ANOVA, Pearson’s correlation, and stepwise multiple regression using SPSS 21. Results: There were significant differences in QoL in terms of sex, age, education, and marital status. There were significant differences in HPL in terms of gender, age and education (P < 0.05) There was a statistically significant association between QoL and HPL in the elderly (r = 0.42, P < 0.05). Based on HPLP II constructs, the significant predicting factors of QoL in the elderly consisted of spiritual growth, stress management, and physical activity (P < 0.05). Conclusions: Health providers should improve the QoL in the elderly by facilitating HPL through health-promoting interventions, which will maintain and increase physical activity, stress management, and spiritual growth. PMID:25593729

  16. Standardization of hormone determinations.

    PubMed

    Stenman, Ulf-Håkan

    2013-12-01

    Standardization of hormone determinations is important because it simplifies interpretation of results and facilitates the use of common reference values for different assays. Progress in standardization has been achieved through the introduction of more homogeneous hormone standards for peptide and protein hormones. However, many automated methods for determinations of steroid hormones do not provide satisfactory result. Isotope dilution-mass spectrometry (ID-MS) has been used to establish reference methods for steroid hormone determinations and is now increasingly used for routine determinations of steroids and other low molecular weight compounds. Reference methods for protein hormones based on MS are being developed and these promise to improve standardization.

  17. Plant Sex Determination.

    PubMed

    Pannell, John R

    2017-03-06

    Sex determination is as important for the fitness of plants as it is for animals, but its mechanisms appear to vary much more among plants than among animals, and the expression of gender in plants differs in important respects from that in most animals. In this Minireview, I provide an overview of the broad variety of ways in which plants determine sex. I suggest that several important peculiarities of plant sex determination can be understood by recognising that: plants show an alternation of generations between sporophytic and gametophytic phases (either of which may take control of sex determination); plants are modular in structure and lack a germ line (allowing for a quantitative expression of gender that is not common in animals); and separate sexes in plants have ultimately evolved from hermaphroditic ancestors. Most theorising about sex determination in plants has focused on dioecious species, but we have much to learn from monecious or hermaphroditic species, where sex is determined at the level of modules, tissues or cells. Because of the fundamental modularity of plant development and potentially important evolutionary links between monoecy and dioecy, it may be useful to relax the distinction often made between 'developmental sex determination' (which underpins the development of male versus female flowers in monoecious species) and 'genetic sex determination' (which underpins the separation of males and females in dioecious species, often mediated by a genetic polymorphism and sex chromosomes). I also argue for relaxing the distinction between sex determination involving a genetic polymorphism and that involving responses to environmental or hormonal cues, because non-genetic cues might easily be converted into genetic switches.

  18. Temperature determination using pyrometry

    DOEpatents

    Breiland, William G.; Gurary, Alexander I.; Boguslavskiy, Vadim

    2002-01-01

    A method for determining the temperature of a surface upon which a coating is grown using optical pyrometry by correcting Kirchhoff's law for errors in the emissivity or reflectance measurements associated with the growth of the coating and subsequent changes in the surface thermal emission and heat transfer characteristics. By a calibration process that can be carried out in situ in the chamber where the coating process occurs, an error calibration parameter can be determined that allows more precise determination of the temperature of the surface using optical pyrometry systems. The calibration process needs only to be carried out when the physical characteristics of the coating chamber change.

  19. Ultrasonic material property determinations

    NASA Technical Reports Server (NTRS)

    Serabian, S.

    1986-01-01

    The use and potential offered by ultrasonic velocity and attenuation measurements to determine and/or monitor material properties is explored. The basis for such unique measurements along with examples of materials from a variety of industries are presented.

  20. Yield-pressure determination

    NASA Technical Reports Server (NTRS)

    Wakefield, M. E.

    1977-01-01

    Stress/strain relationship of complex-shape vessel is recorded under hydrostatic pressure. Technique is used to test pressurized gas cylinders and tubular transition joints made of dissimilar metals and to determine burst or system-failure pressures.

  1. Structural Determination of Circulation.

    ERIC Educational Resources Information Center

    Blankenburg, William B.

    1981-01-01

    Analyzes the effects of both structural factors (demographics, economic conditions, and competition) and discretionary factors (content, design, and marketing techniques) and concludes that it is the former that determine a newspaper's circulation. (FL)

  2. Determining postural stability

    NASA Technical Reports Server (NTRS)

    Lieberman, Erez (Inventor); Forth, Katharine E. (Inventor); Paloski, William H. (Inventor)

    2011-01-01

    A method for determining postural stability of a person can include acquiring a plurality of pressure data points over a period of time from at least one pressure sensor. The method can also include the step of identifying a postural state for each pressure data point to generate a plurality of postural states. The method can include the step of determining a postural state of the person at a point in time based on at least the plurality of postural states.

  3. Protein Nitrogen Determination

    NASA Astrophysics Data System (ADS)

    Nielsen, S. Suzanne

    The protein content of foods can be determined by numerous methods. The Kjeldahl method and the nitrogen combustion (Dumas) method for protein analysis are based on nitrogen determination. Both methods are official for the purposes of nutrition labeling of foods. While the Kjeldahl method has been used widely for over a hundred years, the recent availability of automated instrumentation for the Dumas method in many cases is replacing use of the Kjeldahl method.

  4. Brain Death Determination.

    PubMed

    Spinello, Irene M

    2015-09-01

    In the United States, each year 1% to 2% of deaths are brain deaths. Considerable variation in the practice of determining brain death still remains, despite the publication of practice parameters in 1995 and an evidence-based guideline update in 2010. This review is intended to give bedside clinicians an overview of definition, the causes and pitfalls of misdiagnosing brain death, and a focus on the specifics of the brain death determination process.

  5. Solids mass flow determination

    DOEpatents

    Macko, Joseph E.

    1981-01-01

    Method and apparatus for determining the mass flow rate of solids mixed with a transport fluid to form a flowing mixture. A temperature differential is established between the solids and fluid. The temperature of the transport fluid prior to mixing, the temperature of the solids prior to mixing, and the equilibrium temperature of the mixture are monitored and correlated in a heat balance with the heat capacities of the solids and fluid to determine the solids mass flow rate.

  6. Reference gene selection, primer design and amplification interference of quantitative real-time PCR in tomato and orange subjected to environmental and disease stress

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Response of gene expression in the oxylipin pathway to chilling and heating in tomatoes at full ripe stage was investigated. Total RNA was isolated from tomato pericarp tissue, and gene expression of Tomlox A-Tomlox D, HPL and ADH were determined by real-time Polymerase Chain Reaction (PCR) using t...

  7. [Leucocyte alkaline phosphatase in normal and pathological pregnancy (author's transl)].

    PubMed

    Stark, K H; Zaki, I; Sobolewski, K

    1981-01-01

    The activities of leucocyte alkaline phosphatase were determined in 511 patients with normal and pathological pregnancy. Mean values were compared and the enzyme followed up, and the conclusion was drawn that leucocyte alkaline phosphatase was no safe indicator of foetal condition. No direct relationship were found to exist between leucocyte alkaline phosphatase, total oestrogens, HSAP, HLAP, HPL, and oxytocinase.

  8. HEU age determination

    SciTech Connect

    Moorthy, A.R.; Kato, W.Y.

    1997-07-01

    A new technique has been developed to determine the age of highly enriched uranium (HEU) in solids. Uranium age is defined as the time since the uranium-containing material was last subjected to a process capable of separating uranium from its radioactive-decay daughters. [Most chemical processing, uranium enrichment, volatilization processes, and phase transformations (especially relevant for uranium hexafluoride) can result in separation of the uranium parent material from the decay-product daughters.] Determination of the uranium age, as defined here, may be relevant in verifying arms-control agreements involving uranium-containing nuclear weapons. The HEU age is determined from the ratios of relevant uranium daughter isotopes and their parents, viz {sup 230}Th/{sup 234}U and {sup 231}Pa/{sup 235}U. Uranium isotopes are quantitatively measured by their characteristic gamma rays and their daughters by alpha spectroscopy. In some of the samples, where HEU is enriched more than 99%, the only mode of HEU age determination is by the measurement of {sup 231}Pa since there is negligible quantity of {sup 230}Th due to very low atom concentrations of {sup 234}U in the samples. In this report the methodology and the data for determining the age of two HEU samples are presented.

  9. HEU age determination

    SciTech Connect

    Moorthy, A.R.; Kato, W.Y.

    1995-08-01

    A technique has been developed to determine the Highly Enriched Uranium (HEU) Age which is defined as the time since the HEU was produced in an enrichment process. The HEU age is determined from the ratios of relevant uranium parents and their daughters viz {sup 230}Th/{sup 234}U and {sup 231}Pa/{sup 235}U. Uranium isotopes are quantitatively measured by their characteristic gammas and their daughters by alpha spectroscopy. In some of the samples where HEU is enriched more than 99%, the only mode of HEU age determination is by the measurement of {sup 231}Pa since there is negligible quantity of {sup 230}Th due to very low atom concentrations of {sup 234}U in the sample. In this paper we have presented data and methodology of finding the age of two HEU samples.

  10. Determinants of marriage dissolution

    NASA Astrophysics Data System (ADS)

    Rahim, Mohd Amirul Rafiq Abu; Shafie, Siti Aishah Mohd; Hadi, Az'lina Abdul; Razali, Nornadiah Mohd; Azid @ Maarof, Nur Niswah Naslina

    2015-10-01

    Nowadays, the number of divorce cases among Muslim couples is very worrisome whereby the total cases reported in 2013 increased by half of the total cases reported in the previous year. The questions on the true key factors of dissolution of marriage continue to arise. Thus, the objective of this study is to reveal the factors that contribute to the dissolution of marriage. A total of 181 cases and ten potential determinants were included in this study. The potential determinants considered were age at marriage of husband and wife, educational level of husband and wife, employment status of husband and wife, income of husband and wife, the number of children and the presence at a counseling session. Logistic regression analysis was used to analyze the data. The findings revealed that four determinants, namely the income of husband and wife, number of children and the presence at a counselling session were significant in predicting the likelihood of divorce among Muslim couples.

  11. Ultrasonic determination of recrystallization

    NASA Technical Reports Server (NTRS)

    Generazio, E. R.

    1986-01-01

    Ultrasonic attenuation was measured for cold worked Nickel 200 samples annealed at increasing temperatures. Localized dislocation density variations, crystalline order and colume percent of recrystallized phase were determined over the anneal temperature range using transmission electron microscopy, X-ray diffraction, and metallurgy. The exponent of the frequency dependence of the attenuation was found to be a key variable relating ultrasonic attenuation to the thermal kinetics of the recrystallization process. Identification of this key variable allows for the ultrasonic determination of onset, degree, and completion of recrystallization.

  12. Evidence for communality in the primary determinants of CYP74 catalysis and of structural similarities between CYP74 and classical mammalian P450 enzymes.

    PubMed

    Hughes, Richard K; Yousafzai, Faridoon K; Ashton, Ruth; Chechetkin, Ivan R; Fairhurst, Shirley A; Hamberg, Mats; Casey, Rod

    2008-09-01

    In silico structural analysis of CYP74C3, a membrane-associated P450 enzyme from the plant Medicago truncatula (barrel medic) with hydroperoxide lyase (HPL) specificity, showed that it had strong similarities to the structural folds of the classical microsomal P450 enzyme from rabbits (CYP2C5). It was not only the secondary structure predictions that supported the analysis but site directed mutagenesis of the substrate interacting residues was also consistent with it. This led us to develop a substrate-binding model of CYP74C3 which predicted three amino acid residues, N285, F287, and G288 located in the putative I-helix and distal haem pocket of CYP74C3 to be in close proximity to the preferred substrate 13-HPOTE. These residues were judged to be in equivalent positions to those identified in SRS-4 of CYP2C5. Significance of the residues and their relevance to the model were further assessed by site directed mutagenesis of the three residues followed by EPR spectroscopic and detailed kinetic investigations of the mutated proteins in the presence and absence of detergent. Although point mutation of the residues had no effect on the haem content of the mutated proteins, significant effects on the spin state equilibrium of the haem iron were noted. Kinetic effects of the mutations, which were investigated using three different substrates, were dramatic in nature. In the presence of detergent with the preferred substrate (13-HPOTE), the catalytic center activities and substrate binding affinities of the mutant proteins were reduced by a factor of 8-32 and 4-12, respectively, compared with wild-type--a two orders of magnitude reduction in catalytic efficiencies. We believe this is the first report where primary determinants of catalysis for any CYP74 enzyme, which are fully consistent with our model, have been identified. Our working model predicts that N285 is close enough to suggest that a hydrogen bond with the peroxy group of the enzyme substrate 13-HPOTE is

  13. Determining TOC in Waters

    ERIC Educational Resources Information Center

    Kehoe, Thomas J.

    1977-01-01

    The instrumental method for detecting total organic carbon (TOC) in water samples is detailed. The method's limitations are discussed and certain precautions that must be taken are emphasized. The subject of TOC versus COD and BOD is investigated and TOC is determined to be a valid indication of biological demand. (BT)

  14. Determinants of Disciplinary Discontent.

    ERIC Educational Resources Information Center

    Hargens, Lowell L.; Kelly-Wilson, Lisa

    1994-01-01

    Data from the 1984 Carnegie survey of faculty at U.S. universities show substantial disciplinary variation in pessimism that one's field is stagnant. Field-level variations in both anomie and consensus exert strong effects on average levels of scholarly pessimism within fields and are stronger determinants of scholarly pessimism than individual…

  15. Determinants of project success

    NASA Technical Reports Server (NTRS)

    Murphy, D. C.; Baker, B. N.; Fisher, D.

    1974-01-01

    The interactions of numerous project characteristics, with particular reference to project performance, were studied. Determinants of success are identified along with the accompanying implications for client organization, parent organization, project organization, and future research. Variables are selected which are found to have the greatest impact on project outcome, and the methodology and analytic techniques to be employed in identification of those variables are discussed.

  16. Gender determination in populus

    SciTech Connect

    McLetchie, D.N.; Tuskan, G.A.

    1994-12-31

    Gender, the expression of maleness or femaleness, in dioecious plants has been associated with changes in morphology, physiology, ecological position, and commercial importance of several species, including members of the Salicaceae family. Various mechanisms have been proposed to explain the expression of gender in Salicaceae, including sex chromosomes, simple Mendelian genes, quantitative genes, environment, and genotype-by-environment interactions. Published reports would favor a genetic basis for gender. The objective of this study was to identify molecular markers associated with gender in a segregating family of hybrid poplars. Bulked segregant analysis and chi-squared analysis were used to test for the occurrence of sex chromosomes, individual loci, and chromosome ratios (i.e., ploidy levels) as the mechanisms for gender determination. Examination of 2488 PCR based RAPD markers from 1219 primers revealed nine polymorphic bands between male and female bulked samples. However, linkage analysis indicated that none of these markers were significantly associated with gender. Chisquared results for difference in male-to-female ratios between diploid and triploid genotypes also revealed no significant differences. These findings suggest gender is not controlled via sex chromosomes, simple Mendelian loci or ratios of autosome to gender-determining loci. It is possible that gender is determined genetically by regions of the genome not sampled by the tested markers or by a complex of loci operating in an additive threshold manner or in an epistatic manner. It is also possible that gender is determined environmentally at an early zygote stage, canalizing gender expression.

  17. Determination of Fat Content

    NASA Astrophysics Data System (ADS)

    Carpenter, Charles

    The term "lipid" refers to a group of compounds that are sparingly soluble in water, but show variable solubility in a number of organic solvents (e.g., ethyl ether, petroleum ether, acetone, ethanol, methanol, benzene). The lipid content of a food determined by extraction with one solvent may be quite different from the lipid content as determined with another solvent of different polarity. Fat content is determined often by solvent extraction methods (e.g., Soxhlet, Goldfish, Mojonnier), but it also can be determined by nonsolvent wet extraction methods (e.g., Babcock, Gerber), and by instrumental methods that rely on the physical and chemical properties of lipids (e.g., infrared, density, X-ray absorption). The method of choice depends on a variety of factors, including the nature of the sample (e.g., dry versus moist), the purpose of the analysis (e.g., official nutrition labeling or rapid quality control), and instrumentation available (e.g., Babcock uses simple glassware and equipment; infrared requires an expensive instrument).

  18. Ultrasonic Determination Of Recrystallization

    NASA Technical Reports Server (NTRS)

    Generazio, Edward R.

    1988-01-01

    State of recrystallization identified. Measurement of ultrasonic attenuation shows promise as means of detecting recrystallization in metal. Technique applicable to real-time acoustic monitoring of thermomechanical treatments. Starting with work-hardened material, one ultrasonically determines effect of annealing, using correlation between ultrasonic attenuation and temperature.

  19. Determinants of translation ambiguity

    PubMed Central

    Degani, Tamar; Prior, Anat; Eddington, Chelsea M.; Arêas da Luz Fontes, Ana B.; Tokowicz, Natasha

    2016-01-01

    Ambiguity in translation is highly prevalent, and has consequences for second-language learning and for bilingual lexical processing. To better understand this phenomenon, the current study compared the determinants of translation ambiguity across four sets of translation norms from English to Spanish, Dutch, German and Hebrew. The number of translations an English word received was correlated across these different languages, and was also correlated with the number of senses the word has in English, demonstrating that translation ambiguity is partially determined by within-language semantic ambiguity. For semantically-ambiguous English words, the probability of the different translations in Spanish and Hebrew was predicted by the meaning-dominance structure in English, beyond the influence of other lexical and semantic factors, for bilinguals translating from their L1, and translating from their L2. These findings are consistent with models postulating direct access to meaning from L2 words for moderately-proficient bilinguals. PMID:27882188

  20. Sex determination in Chlamydomonas.

    PubMed

    Goodenough, Ursula; Lin, Huawen; Lee, Jae-Hyeok

    2007-06-01

    The sex-determination system of the unicellular green alga, Chlamydomonas reinhardtii, is governed by genes in the mating-type (MT) locus and entails additional genes located in autosomes. Gene expression is initiated by nitrogen starvation, and cells differentiate into plus or minus gametes within 6h. Reviewed is our current understanding of gametic differentiation and fertilization, initiation of zygote development, and the uniparental inheritance of organelle genomes.

  1. Radio determination satellite service

    NASA Astrophysics Data System (ADS)

    Briskman, Robert D.

    1990-07-01

    The capabilities and measured performance of a geosynchronous satellite-based service called the radio determination satellite service (RDSS), which operates at radio frequencies allocated by the International Telecommunications Union (ITU) and is licensed in the United States by the Federal Communications Commission (FCC), are discussed. Plans for both improvement in capability and expansion to nearly global coverage are described. Since RDSS can also provide radio navigation, some comparisons of this service with the Global Positioning System (GPS) are made.

  2. Statistical initial orbit determination

    SciTech Connect

    Taff, L.G.; Belkin, B.; Schweiter, G.A.; Sommar, K. D.H. Wagner Associates, Inc., Paoli, PA )

    1992-02-01

    For the ballistic missile initial orbit determination problem in particular, the concept of 'launch folders' is extended. This allows to decouple the observational data from the initial orbit determination problem per se. The observational data is only used to select among the possible orbital element sets in the group of folders. Monte Carlo simulations using up to 7200 orbital element sets are described. The results are compared to the true orbital element set and the one a good radar would have been able to produce if collocated with the optical sensor. The simplest version of the new method routinely outperforms the radar initial orbital element set by a factor of two in future miss distance. In addition, not only can a differentially corrected orbital element set be produced via this approach - after only two measurements of direction - but also an updated, meaningful, six-dimensional covariance array for it can be calculated. This technique represents a significant advance in initial orbit determination for this problem, and the concept can easily be extended to minor planets and artificial satellites. 9 refs.

  3. Why social determinants?

    PubMed

    Halfon, Neal; Larson, Kandyce; Russ, Shirley

    2010-01-01

    There is overwhelming evidence that social factors have profound influences on health. Children are particularly sensitive to social determinants, especially in the early years. Life course models view health as a developmental process, the product of multiple gene and environment interactions. Adverse early social exposures become programmed into biological systems, setting off chains of risk that can result in chronic illness in mid-life and beyond. Positive health-promoting influences can set in motion a more virtuous and health-affirming cycle, leading to more optimal health trajectories. Mounting an effective response to social determinants will involve both direct social policy initiatives designed to eliminate poverty and inequality, and indirect approaches focused on disrupting pathways between social risks and poor health outcomes. To be effective, these indirect strategies will require nothing short of a transformation of existing child health systems. Parents and professionals must work together from the ground up, raising public awareness about social determinants of health and implementing cross-sector place-based initiatives designed to promote positive health in childhood.

  4. The Determination of Downwash

    NASA Technical Reports Server (NTRS)

    Diehl, Walter S

    1921-01-01

    It is obvious that, in accordance with Newton's second law, the lift on an aerofoil must be equal to the vertical momentum communicated per second to the air mass affected. Consequently a lifting aerofoil in flight is trailed by a wash which has a definite inclination corresponding to the factors producing the lift. It is thought that sufficient data, theoretical and experimental, are now available for a complete determination of this wash with respect to the variation of its angle of inclination to the originating aerofoil and with respect to the law which governs its decay in space.

  5. Satellite altitude determination uncertainties

    NASA Technical Reports Server (NTRS)

    Siry, J. W.

    1972-01-01

    Satellite altitude determination uncertainties will be discussed from the standpoint of the GEOS-C satellite, from the longer range viewpoint afforded by the Geopause concept. Data are focused on methods for short-arc tracking which are essentially geometric in nature. One uses combinations of lasers and collocated cameras. The other method relies only on lasers, using three or more to obtain the position fix. Two typical locales are looked at, the Caribbean area, and a region associated with tracking sites at Goddard, Bermuda and Canada which encompasses a portion of the Gulf Stream in which meanders develop.

  6. Mass determination of neutrinos

    NASA Technical Reports Server (NTRS)

    Chiu, Hong-Yee

    1988-01-01

    A time-energy correlation method has been developed to determine the signature of a nonzero neutrino mass in a small sample of neutrinos detected from a distant source. The method is applied to the Kamiokande II (Hirata et al., 1987) and IMB (Bionta et al., 1987) observations of neutrino bursts from SN 1987A. Using the Kamiokande II data, the neutrino rest mass is estimated at 2.8 + 2.0, - 1.4 eV and the initial neutrino pulse is found to be less than 0.3 sec full width, followed by an emission tail lasting at least 10 sec.

  7. Determination of nonaxisymmetric equilibrium

    SciTech Connect

    Elkin, D.

    1980-01-01

    The Princeton Equilibrium Code is modified to determine the equilibrium surfaces for a large aspect ratio toroidal system with helical magnetic fields. The code may easily be made to include any variety of modes. Verification of the code is made by comparison with an analytic solution for l = 3. Previously observed shifting of the magnetic axis with increasing pressure or with a changed externally applied vertical field is obtained. The case l = 0, a bumpy torus, gives convergence only for the lenient convergence tolerance of epsilon/sub b/ = 1.0 x 10-/sup 2/.

  8. Embryonic determination and differentiation.

    PubMed

    Ingram, V M; Keane, R W

    1980-04-01

    At the cellular level, development proceeds in a series of stages in which precursor cells are first restricted in their developmental potential (determination) and subsequently express their genetic information as specific tissues (differentiation). This paper discusses the problems encountered in seeking to understand the molecular mechanisms of thes processes and describes several model systems. A novel approach involves the inhibition of differentiation by virus transformation of the precursor cells in the chick primary mesenchyme, The transformed cells are cloned, grown to large numbers, and then analyzed biochemically.

  9. Determination of Survivable Fires

    NASA Technical Reports Server (NTRS)

    Dietrich, D. L.; Niehaus, J. E.; Ruff, G. A.; Urban, D. L.; Takahashi, F.; Easton, J. W.; Abbott, A. A.; Graf, J. C.

    2012-01-01

    At NASA, there exists no standardized design or testing protocol for spacecraft fire suppression systems (either handheld or total flooding designs). An extinguisher's efficacy in safely suppressing any reasonable or conceivable fire is the primary benchmark. That concept, however, leads to the question of what a reasonable or conceivable fire is. While there exists the temptation to over-size' the fire extinguisher, weight and volume considerations on spacecraft will always (justifiably) push for the minimum size extinguisher required. This paper attempts to address the question of extinguisher size by examining how large a fire a crew member could successfully survive and extinguish in the confines of a spacecraft. The hazards to the crew and equipment during an accidental fire include excessive pressure rise resulting in a catastrophic rupture of the vehicle skin, excessive temperatures that burn or incapacitate the crew (due to hyperthermia), carbon dioxide build-up or other accumulation of other combustion products (e.g. carbon monoxide). Estimates of these quantities are determined as a function of fire size and mass of material burned. This then becomes the basis for determining the maximum size of a target fire for future fire extinguisher testing.

  10. Determination of radar MTF

    SciTech Connect

    Chambers, D.

    1994-11-15

    The ultimate goal of the Current Meter Array (CMA) is to be able to compare the current patterns detected with the array with radar images of the water surface. The internal wave current patterns modulate the waves on the water surface giving a detectable modulation of the radar cross-section (RCS). The function relating the RCS modulations to the current patterns is the Modulation Transfer Function (MTF). By comparing radar images directly with co-located CMA measurements the MTF can be determined. In this talk radar images and CMA measurements from a recent experiment at Loch Linnhe, Scotland, will be used to make the first direct determination of MTF for an X and S band radar at low grazing angles. The technical problems associated with comparing radar images to CMA data will be explained and the solution method discussed. The results suggest the both current and strain rate contribute equally to the radar modulation for X band. For S band, the strain rate contributes more than the current. The magnitude of the MTF and the RCS modulations are consistent with previous estimates when the wind is blowing perpendicular to the radar look direction.

  11. Adaptive interplanetary orbit determination

    NASA Astrophysics Data System (ADS)

    Crain, Timothy Price

    This work documents the development of a real-time interplanetary orbit determination monitoring algorithm for detecting and identifying changes in the spacecraft dynamic and measurement environments. The algorithm may either be utilized in a stand-alone fashion as a spacecraft monitor and hypothesis tester by navigators or may serve as a component in an autonomous adaptive orbit determination architecture. In either application, the monitoring algorithm serves to identify the orbit determination filter parameters to be modified by an offline process to restore the operational model accuracy when the spacecraft environment changes unexpectedly. The monitoring algorithm utilizes a hierarchical mixture-of-experts to regulate a multilevel bank organization of extended Kalman filters. Banks of filters operate on the hierarchy top-level and are composed of filters with configurations representative of a specific environment change called a macromode. Fine differences, or micromodes, within the macromodes are represented by individual filter configurations. Regulation is provided by two levels of single-layer neural networks called gating networks. A single top-level gating network regulates the weighting among macromodes and each bank uses a gating network to regulate member filters internally. Experiments are conducted on the Mars Pathfinder cruise trajectory environment using range and Doppler data from the Deep Space Network. The experiments investigate the ability of the hierarchical mixture-of-experts to identify three environment macromodes: (1) unmodeled impulsive maneuvers, (2) changes in the solar radiation pressure dynamics, and (3) changes in the measurement noise strength. Two methods of initializing the gating networks are examined in each experiment. One method gives the neurons associated with all filters equivalent synaptic weight. The other method places greater weight on the operational filter initially believed to model the spacecraft environment. The

  12. Tracer for circulation determinations

    SciTech Connect

    Moore, H.; Santos, S.; Wysong, R. D.

    1985-03-19

    An improved tracer particle is described comprising an ion exchange core having a polymer coating thereon, the coated ion exchange core having a reaction site capable of reacting with a compound containing an oxirane group, said coated ion exchange core having been treated with a compound containing an oxirane group to react with said coated ion exchange core causing an increase in mass of the tracer particle. Preferably, the ion exchange core is labelled with a radionuclide. These particles have improved characteristics including improved stability against leaching and improved handling properties. Such particles are useful in circulatory determinations involving the injection of the particles as a suspension in a physiologically acceptable carrier or medium into the circulatory system of animals.

  13. Early determinants of obesity.

    PubMed

    Ong, Ken K

    2010-01-01

    High rates of overweight and obesity even in very young children argue the case for strategies to prevent overweight from very young ages. Historical studies, prospective birth cohorts, and more recently genetic studies all indicate that the rapid weight gain trajectory to later obesity starts in the first months of life, even from birth. Early puberty and age at menarche are consequences of rapid infant weight gain and childhood overweight, and in turn these adolescent traits are predictive for obesity, diabetes, hypertension and cardiovascular disease events in later life. Understanding of the nutritional, parental and wider determinants of rapid infant weight gain are informing the development of obesity prevention strategies starting in early life. Such strategies could be further refined by future studies that address the specific regulation of infant adiposity, and also by studies that explore whether these life-course trajectories are modifiable during adolescence.

  14. Complexometric Determination of Calcium

    NASA Astrophysics Data System (ADS)

    Nielsen, S. Suzanne

    Ethylenediaminetetraacetate (EDTA) complexes with numerous mineral ions, including calcium and magnesium. This reaction can be used to determine the amount of these minerals in a sample by a complexometric titration. Endpoints in the titration are detected using indicators that change color when they complex with mineral ions. Calmagite and eriochrome black T (EBT) are such indicators that change from blue to pink when they complex with calcium and magnesium. In the titration of a mineral-containing solution with EDTA, the solution turns from pink to blue at the endpoint with either indicator. The pH affects a complexometric EDTA titration in several ways, and must be carefully controlled. A major application of EDTA titration is testing the hardness of water, for which the method described is an official one (Standard Methods for the Examination of Water and Wastewater, Method 2340C; AOAC Method 920.196).

  15. Automatic Bayesian polarity determination

    NASA Astrophysics Data System (ADS)

    Pugh, D. J.; White, R. S.; Christie, P. A. F.

    2016-07-01

    The polarity of the first motion of a seismic signal from an earthquake is an important constraint in earthquake source inversion. Microseismic events often have low signal-to-noise ratios, which may lead to difficulties estimating the correct first-motion polarities of the arrivals. This paper describes a probabilistic approach to polarity picking that can be both automated and combined with manual picking. This approach includes a quantitative estimate of the uncertainty of the polarity, improving calculation of the polarity probability density function for source inversion. It is sufficiently fast to be incorporated into an automatic processing workflow. When used in source inversion, the results are consistent with those from manual observations. In some cases, they produce a clearer constraint on the range of high-probability source mechanisms, and are better constrained than source mechanisms determined using a uniform probability of an incorrect polarity pick.

  16. Ultratrace determination of curium

    SciTech Connect

    Beitz, J.V.

    1995-02-01

    Development of a method for detection of curium at near single atom levels is being undertaken as a part of the Advanced Concepts Project at Argonne National Laboratory with funding from the US Department of Energy, Office of Arms Control and Nonproliferation. Ultratrace determination of curium, with the ability to quantify the fraction that is curium-242, provides a signature method of detecting clandestine reprocessing of recently irradiated uranium targets. Curium initially present in any of a variety of materials such as air filters, solid or liquid process waste, soil, flora, or fauna can be recovered via current chemical separations processing techniques. Using the ultratrace method being developed, such recovered curium will be quantified with thousand-fold higher sensitivity than the best currently available method which is alpha counting. This high sensitivity arises because, on average, a given trivalent curium (Cm{sup 3+}) ion can emit a very large number of fluorescence photons before alpha decay occurs.

  17. Orbit Determination Toolbox

    NASA Technical Reports Server (NTRS)

    Carpenter, James R.; Berry, Kevin; Gregpru. Late; Speckman, Keith; Hur-Diaz, Sun; Surka, Derek; Gaylor, Dave

    2010-01-01

    The Orbit Determination Toolbox is an orbit determination (OD) analysis tool based on MATLAB and Java that provides a flexible way to do early mission analysis. The toolbox is primarily intended for advanced mission analysis such as might be performed in concept exploration, proposal, early design phase, or rapid design center environments. The emphasis is on flexibility, but it has enough fidelity to produce credible results. Insight into all flight dynamics source code is provided. MATLAB is the primary user interface and is used for piecing together measurement and dynamic models. The Java Astrodynamics Toolbox is used as an engine for things that might be slow or inefficient in MATLAB, such as high-fidelity trajectory propagation, lunar and planetary ephemeris look-ups, precession, nutation, polar motion calculations, ephemeris file parsing, and the like. The primary analysis functions are sequential filter/smoother and batch least-squares commands that incorporate Monte-Carlo data simulation, linear covariance analysis, measurement processing, and plotting capabilities at the generic level. These functions have a user interface that is based on that of the MATLAB ODE suite. To perform a specific analysis, users write MATLAB functions that implement truth and design system models. The user provides his or her models as inputs to the filter commands. The software provides a capability to publish and subscribe to a software bus that is compliant with the NASA Goddard Mission Services Evolution Center (GMSEC) standards, to exchange data with other flight dynamics tools to simplify the flight dynamics design cycle. Using the publish and subscribe approach allows for analysts in a rapid design center environment to seamlessly incorporate changes in spacecraft and mission design into navigation analysis and vice versa.

  18. Age determination of raccoons

    USGS Publications Warehouse

    Grau, G.A.; Sanderson, G.C.; Rogers, J.P.

    1970-01-01

    Age criteria, based on 61 skulls and eye lenses from 103 known-age captives, are described for separating raccoons (Procyon lotor) into eight age-classes as follows: young-of-the-year, 1, 2, 3, 4, 5, 6-7, > 7 years. Criteria studied were eye lens nitrogen, cranial suture closure, tooth wear and incisor cementum layers. Lens nitrogen increased rapidly up to 12 months of age, but at much reduced rate thereafter. Total lens nitrogen was useful only in separating young-of-the-year from adults. The closure sequence for five cranial sutures accurately divided the total known-age sample of males into seven groups, and the adults into five groups. The tooth wear criteria divided the known-age sample into five relative age groups, but aging of individuals by this method was inaccurate. Histological sectioning of known-age teeth was the best method of observing layering in the cementum tissue. The technique of basing estimation of age on cementum ring counts, although subjective, was accurate for aging individuals through their fourth year but tended to underestimate the age of animals over 4 years old. However, suture closure or tooth wear can be used to identify males over 4 years old. In field studies, technical difficulties limit the utility of age estimation by cementum layers. Maximum root thickness of the lower canine was accurate in determining the sex of individuals from 5 months to ,at least 48 months of age.

  19. Pediatric brain death determination.

    PubMed

    Mathur, Mudit; Ashwal, Stephen

    2015-04-01

    Clinical guidelines for the determination of brain death in children were first published in 1987. These guidelines were revised in 2011 under the auspices of the Society of Critical Care Medicine, the American Academy of Pediatrics, and the Child Neurology Society, and provide the minimum standards that must be satisfied before brain death can be declared in infants and children. After achieving physiologic stability and exclusion of confounders, two examinations including apnea testing separated by an observation period (24 hours for term newborns up to 30 days of age, and 12 hours for infants and children from 31 days up to 18 years) are required to establish brain death. Apnea testing should demonstrate a final arterial PaCO2 20 mm Hg above the baseline and ≥ 60 mm Hg with no respiratory effort during the testing period. Ancillary studies (electroencephalogram and radionuclide cerebral blood flow) are not required to establish brain death and are not a substitute for the neurologic examination. The committee concluded that ancillary studies may be used (1) when components of the examination or apnea testing cannot be completed, (2) if uncertainty about components of the neurologic examination exists, (3) if a medication effect may be present, or (4) to reduce the interexamination observation period. When ancillary studies are used, a second clinical examination and apnea test should still be performed and components that can be completed must remain consistent with brain death.

  20. Epidemiological determinants of psoriasis.

    PubMed

    Islam, M T; Paul, H K; Zakaria, S M; Islam, M M; Shafiquzzaman, M

    2011-01-01

    A cross-sectional study was conducted on 102 cases having clinical manifestation of psoriasis with a view to evaluate the epidemiological determinants of psoriasis. Psoriasis constituted 1.49% of the total dermatological disorder. Seventy patients (68.6%) were males and thirty two (31.4%) were females with a male to female ratio of 2.18:1. The mean age was 30.76±13.17 years in male and 26.94±14.94 years in female. Sixteen (15.7%) patients had one or more family member having psoriasis with male and female in equal frequency. Regarding precipitating factors, psoriasis was developed after trauma in 4.9%, infection 3.9%, stressful life events 6.9% and drugs 2.9%; and was exacerbated after trauma in 5.9%, infection 5.9%, stressful life events 35.3% and drugs 12.7%. The disease showed improvement in summer (27.5%) and found deteriorated in winter (47.1%). Sunlight had beneficial effect in 33.3% of cases. During pregnancy improvement was observed in 50% but flare up in 22.2% of cases. Fifty percent of patients were smokers, 41.2% were non-smokers and 13.7% were ex-smokers. Forty percent had Body Mass Index (BMI) between 22 to 26 Kg/m², 40.2% had less than 22 Kg/m² and 15.7% had above 26 Kg/m². It was concluded that the prevalence of psoriasis among dermatological patients was similar to results reported in Turkey and in Northern India. The precipitating factors, such as smoking, stressful life events, infection, trauma, sunlight, pregnancy, drugs, and seasonal variations could influence the development of psoriasis and affect its clinical expression.

  1. Determinants of lemming outbreaks.

    PubMed

    Ims, Rolf A; Yoccoz, Nigel G; Killengreen, Siw T

    2011-02-01

    Population outbreaks in tundra rodents have intrigued scientists for a century as a result of their spectacular appearances and their general lessons in ecology. One outstanding question that has led to competing hypotheses is why sympatric lemmings and voles differ in regularity and shape of their outbreaks. Lemming outbreaks may be lost for decades while vole populations maintain regular population cycles. Moreover, when lemming populations eventually irrupt, they do so more steeply than the vole populations. Norwegian lemmings exhibited a large-scale outbreak synchronously with gray-sided voles in Finnmark, northern Fennoscandia, during 2006 to 2007 for the first time in two decades. Analyses of spatial variability of this outbreak across altitudinal gradients allowed us to identify determinants of the contrasting lemming and vole dynamics. The steeper lemming outbreak trajectories were caused by breeding and population growth during winter, when nonbreeding vole populations consistently declined. The differently shaped lemming and vole outbreaks appear to result from a particular demographic tactic of lemmings that evolved as an adaptation to the long and cold Arctic-Alpine winters. The lemming outbreak amplitude increased with altitude and vole density, indicating that lemming outbreaks are jointly facilitated by low temperatures and apparent mutualism with voles mediated by shared predators. High sensitivity to variation in climate and predation is likely to be the reasons why lemmings have more erratic population dynamics than sympatric voles. The combination of continued climatic warming and dampened vole cycles is expected to further decrease the frequency, amplitude, and geographic range of lemming outbreaks in tundra ecosystems.

  2. Enkephalins and hormonal-metabolic reactions in experimental stress depending on its severity

    SciTech Connect

    Lishmanov, Y.B.; Alekminskaya, L.A.; Lasukova, T.V.

    1985-08-01

    The aim of this investigation was to study the action of enkephalins on changes in hormonal-metabolic constants in stress of varied severity. Catecholamine excretion with the urine was determined fluorometrically, serum cortisol and insulin concentrations were measured radioimmunologically and glucose was determined by the standard orthotoluidine method. The results of the investigation indicate that enkephalins have a modulating effect on various hormonal mechanisms of adaptation stress. The results confirm that the physiological action of the peptide regulator depends on the functional state of the biological systems and it may differ sharply, even to the extent of diametrically opposite effects.

  3. Associations between a health-promoting lifestyle and quality of life among adults with beta-thalassemia major

    PubMed Central

    2016-01-01

    OBJECTIVES A health-promoting lifestyle (HPL) is a factor that affects the quality of life (QoL) in patients with beta-thalassemia (β-thalassemia). Due to the lack of studies of this issue, this study aimed to determine the association between HPL and QoL among adults with β-thalassemia. METHODS This cross-sectional (descriptive-analytic) study was conducted among 389 adult patients with β-thalassemia in Tehran, Iran. The research instrument included a questionnaire consisting of three parts: demographic items, the Short-Form Health Survey and the Health-Promoting Lifestyle Profile. The data were analyzed using SPSS version 23.0. The results were considered significant at the conventional p<0.05 level. RESULTS The mean age of the participants was 30.2±8.3 years. The mean score of the HPL dimensions was 127.28±21.53, and the mean score of the QoL domains was 61.44±23.38. The highest and the lowest mean scores of the HPL dimensions were found for spiritual growth (23.96±5.74) and physical activity (11.32±3.95), respectively. The QoL scores in all three domains (total, physical component summary score, and mental component summary score) were moderate. Health responsibility, physical activity, spiritual growth, and interpersonal relations were significant predictive factors of QoL in adults with β-thalassemia; these four dimensions explained 37.9% of the variance in QoL. CONCLUSIONS QoL and HPL were not at acceptable levels among patients with thalassemia. Therefore, educational interventions emphasizing spiritual growth, physical activity, and interpersonal relations are necessary for patients with thalassemia. PMID:27857026

  4. Determinants for grading Malaysian rice

    NASA Astrophysics Data System (ADS)

    ChePa, Noraziah; Yusoff, Nooraini; Ahmad, Norhayati

    2016-08-01

    Due to un-uniformity of rice grading practices in Malaysia, zones which actively producing rice in Malaysia are using their own way of grading rice. Rice grading is important in determining rice quality and its subsequent price in the market. It is an important process applied in the rice production industry with the purpose of ensuring that the rice produced for the market meets the quality requirements of consumer. Two important aspects that need to be considered in determining rice grades are grading technique and determinants to be used for grading (usually referred as rice attributes). This article proposes the list of determinants to be used in grading Malaysian rice. Determinants were explored through combination of extensive literature review and series of interview with the domain experts and practitioners. The proposed determinants are believed to be beneficial to BERNAS in improving the current Malaysian rice grading process.

  5. Determinants of Service Contract Outcomes

    DTIC Science & Technology

    2011-04-30

    distribution unlimited. Prepared for the Naval Postgraduate School, Monterey, California 93943 NPS-AM-11-C8P08R01-036 Determinants of Service...2. REPORT TYPE 3. DATES COVERED 00-00-2011 to 00-00-2011 4. TITLE AND SUBTITLE Determinants of Service Contract Outcomes 5a. CONTRACT NUMBER...specification and measurement of contractor performance problematic. Despite these difficulties, little research has been conducted to examine the determinants

  6. Perchlorate Regulatory Determination Fact Sheets

    EPA Pesticide Factsheets

    Fact sheets have been developed for the perchlorate regulatory determination corresponding to the following stages published in the Federal Register: Final, Supplemental request for comments, and Preliminary.

  7. The Resurgence of Biological Determinism.

    ERIC Educational Resources Information Center

    Segal, Elizabeth A.; Kilty, Keith M.

    1998-01-01

    Addresses two areas where science has been and still is used to justify policies and attitudes that are discriminatory and oppressive: homosexuality and alcoholism. This article analyzes the debate over whether these correlations are biologically or socially determined. Of particular concern is the potential impact of biological determinism on the…

  8. Precise Orbit Determination for ALOS

    NASA Technical Reports Server (NTRS)

    Nakamura, Ryo; Nakamura, Shinichi; Kudo, Nobuo; Katagiri, Seiji

    2007-01-01

    The Advanced Land Observing Satellite (ALOS) has been developed to contribute to the fields of mapping, precise regional land coverage observation, disaster monitoring, and resource surveying. Because the mounted sensors need high geometrical accuracy, precise orbit determination for ALOS is essential for satisfying the mission objectives. So ALOS mounts a GPS receiver and a Laser Reflector (LR) for Satellite Laser Ranging (SLR). This paper deals with the precise orbit determination experiments for ALOS using Global and High Accuracy Trajectory determination System (GUTS) and the evaluation of the orbit determination accuracy by SLR data. The results show that, even though the GPS receiver loses lock of GPS signals more frequently than expected, GPS-based orbit is consistent with SLR-based orbit. And considering the 1 sigma error, orbit determination accuracy of a few decimeters (peak-to-peak) was achieved.

  9. Method of determining glass durability

    DOEpatents

    Jantzen, C.M.; Pickett, J.B.; Brown, K.G.; Edwards, T.B.

    1998-12-08

    A process is described for determining one or more leachate concentrations of one or more components of a glass composition in an aqueous solution of the glass composition by identifying the components of the glass composition, including associated oxides, determining a preliminary glass dissolution estimator, {Delta}G{sub p}, based upon the free energies of hydration for the component reactant species, determining an accelerated glass dissolution function, {Delta}G{sub a}, based upon the free energy associated with weak acid dissociation, {Delta}G{sub a}{sup WA}, and accelerated matrix dissolution at high pH, {Delta}G{sub a}{sup SB} associated with solution strong base formation, and determining a final hydration free energy, {Delta}G{sub f}. This final hydration free energy is then used to determine leachate concentrations for elements of interest using a regression analysis and the formula log{sub 10}(N C{sub i}(g/L))=a{sub i} + b{sub i}{Delta}G{sub f}. The present invention also includes a method to determine whether a particular glass to be produced will be homogeneous or phase separated. The present invention is also directed to methods of monitoring and controlling processes for making glass using these determinations to modify the feedstock materials until a desired glass durability and homogeneity is obtained. 4 figs.

  10. Method of determining glass durability

    DOEpatents

    Jantzen, Carol Maryanne; Pickett, John Butler; Brown, Kevin George; Edwards, Thomas Barry

    1998-01-01

    A process for determining one or more leachate concentrations of one or more components of a glass composition in an aqueous solution of the glass composition by identifying the components of the glass composition, including associated oxides, determining a preliminary glass dissolution estimator, .DELTA.G.sub.p, based upon the free energies of hydration for the component reactant species, determining an accelerated glass dissolution function, .DELTA.G.sub.a, based upon the free energy associated with weak acid dissociation, .DELTA.G.sub.a.sup.WA, and accelerated matrix dissolution at high pH, .DELTA.G.sub.a.sup.SB associated with solution strong base formation, and determining a final hydration free energy, .DELTA.G.sub.f. This final hydration free energy is then used to determine leachate concentrations for elements of interest using a regression analysis and the formula log.sub.10 (N C.sub.i (g/L))=a.sub.i +b.sub.i .DELTA.G.sub.f. The present invention also includes a method to determine whether a particular glass to be produced will be homogeneous or phase separated. The present invention is also directed to methods of monitoring and controlling processes for making glass using these determinations to modify the feedstock materials until a desired glass durability and homogeneity is obtained.

  11. Evans function and Fredholm determinants

    PubMed Central

    Karambal, Issa; Malham, Simon J. A.

    2015-01-01

    We explore the relationship between the Evans function, transmission coefficient and Fredholm determinant for systems of first-order linear differential operators on the real line. The applications we have in mind include linear stability problems associated with travelling wave solutions to nonlinear partial differential equations, for example reaction–diffusion or solitary wave equations. The Evans function and transmission coefficient, which are both finite determinants, are natural tools for both analytic and numerical determination of eigenvalues of such linear operators. However, inverting the eigenvalue problem by the free-state operator generates a natural linear integral eigenvalue problem whose solvability is determined through the corresponding infinite Fredholm determinant. The relationship between all three determinants has received a lot of recent attention. We focus on the case when the underlying Fredholm operator is a trace class perturbation of the identity. Our new results include (i) clarification of the sense in which the Evans function and transmission coefficient are equivalent and (ii) proof of the equivalence of the transmission coefficient and Fredholm determinant, in particular in the case of distinct far fields. PMID:25663806

  12. Step 4: NCI Funding Determinations

    Cancer.gov

    Funding determinations are made around Oct. 1 each federal fiscal year. These decisions take into account several factors, including Congressional mandates, new scientific opportunities and program priorities when deciding which grants receive funding.

  13. Thorium: Determination by CDTN, Brazil

    NASA Astrophysics Data System (ADS)

    Menezes, M. A. B. C.; Sabino, C. V. S.

    1999-01-01

    One of the tasks of the Radiochemical Sector, CDTN/CNEN, Brazil, is to meet the clients' analytical needs. The Sector has been facing the challenges of determining several elements in diversified matrixes from all over the country since the sixties. It has been giving analytical support to universities, industries, environmental monitoring programs, research institutes. Due to the growing need to determine thorium isotopes through the years it was necessary to work out a routine procedures. Nowadays the determination of thorium consists of a well established routine whose procedures are applied to grouped samples according to their kind, physical state, matrix interference, detection limits and number of samples. This paper describes the methods used by CDTN to determine232Th by neutron activation analysis and230Th and228Th by radiochemical separations and alpha spectrometry in several matrixes.

  14. Determination of plutonium metal origins

    SciTech Connect

    Moody, K.J.

    1995-02-01

    Forensic signatures are present in any Pu sample that can determine the sample`s origin: isotopic ratio of Pu, progeny species that grow into the sample, and contaminant species left over from incomplete purification of the Pu in fuel reprocessing. In the context of intelligence information, this can result in attribution of responsibility for the product of clandestine proliferant operations or material smuggled from existing stockpiles. A list of signature elements and what can be determined from them have been developed. Work needs to be done in converting concentrations of signature species into a quantitative forensic analysis, particularly in regard to reactor performance, but this should require only a small effort. A radiochemical analysis scheme has been developed for measuring these nuclides; more work is needed, particularly for determining fission product concentrations. A sample of Pu metal has been analyzed and several parameters determined that are strong indicators of its point of origin.

  15. Gender determination of avian embryo

    DOEpatents

    Daum, Keith A.; Atkinson, David A.

    2002-01-01

    Disclosed is a method for gender determination of avian embryos. During the embryo incubation process, the outer hard shells of eggs are drilled and samples of allantoic fluid are removed. The allantoic fluids are directly introduced into an ion mobility spectrometer (IMS) for analysis. The resulting spectra contain the relevant marker peaks in the positive or negative mode which correlate with unique mobilities which are sex-specific. This way, the gender of the embryo can be determined.

  16. Determining Hostile Intent in Cyberspace

    DTIC Science & Technology

    2014-01-01

    signal corps evolved to encrypt , trans- mit, receive, and handle messages, first at the rate of the written word and the horse, then at the rate of...approach where the “ quantum of damage and not the means of attack” determines if an action in cyberspace is a prohibited use of force.10 This approach...a quantum -of- damage approach is used, the critical question would be who determines what a sufficient amount of damage is to con- stitute a

  17. Sex determination in flowering plants.

    PubMed Central

    Dellaporta, S L; Calderon-Urrea, A

    1993-01-01

    In many ways, plants offer unique systems through which to study sex determination. Because the production of unisexual flowers has evolved independently in many plant species, different and novel mechanisms may be operational. Hence, there is probably not one unifying mechanism that explains sex determination in plants. Advances in our understanding of sex determination will come from the analysis of the genetics, molecular biology, and biochemistry of genes controlling sexual determination in plants. Several excellent model systems for bisexual floral development (Arabidopsis and Antirrhinum), monoecy (maize), and dioecy (Silene, asparagus, and mercury) are available for such analyses. The important questions that remain concern the mechanism of action of sex determination genes and their interrelationship, if any, with homeotic genes that determine the sexual identity of floral organ primordia. At the physiological level, the connection between hormone signaling and sexuality is not well understood, although significant correlations have been discovered. Finally, once the genes that regulate these processes are identified, cloned, and studied, new strategies for the manipulation of sexuality in plants should be forthcoming. PMID:8281039

  18. Lunar Prospector Orbit Determination Results

    NASA Technical Reports Server (NTRS)

    Beckman, Mark; Concha, Marco

    1998-01-01

    The orbit support for Lunar Prospector (LP) consists of three main areas: (1) cislunar orbit determination, (2) rapid maneuver assessment using Doppler residuals, and (3) routine mapping orbit determination. The cislunar phase consisted of two trajectory correction maneuvers during the translunar cruise followed by three lunar orbit insertion burns. This paper will detail the cislunar orbit determination accuracy and the real-time assessment of the cislunar trajectory correction and lunar orbit insertion maneuvers. The non-spherical gravity model of the Moon is the primary influence on the mapping orbit determination accuracy. During the first two months of the mission, the GLGM-2 lunar potential model was used. After one month in the mapping orbit, a new potential model was developed that incorporated LP Doppler data. This paper will compare and contrast the mapping orbit determination accuracy using these two models. LP orbit support also includes a new enhancement - a web page to disseminate all definitive and predictive trajectory and mission planning information. The web site provides definitive mapping orbit ephemerides including moon latitude and longitude, and four week predictive products including: ephemeris, moon latitude/longitude, earth shadow, moon shadow, and ground station view periods. This paper will discuss the specifics of this web site.

  19. [Determination of HDL-cholesterol].

    PubMed

    Herrmann, W; Schütz, C; Reuter, W

    1983-01-01

    For the clinical practice methods of the determination of HDL-cholesterol made their way which are based on the precipitation of apolipoprotein-B-containing lipoproteins and a determination of cholesterol following. The expensive methods of the ultracentrifugation serve as reference methods. The most-spread precipitation techniques (heparin/MCl2, dextran sulphate/CaCl2 or MgCl2 photungstic acid/MgCl2) are comparatively observed with regard to their effectiveness, practicability and methodical and technical conditions (influence of the concentration of the precipitation reagents, pH-value, temperature, incubation and centrifugation conditions). Results of own investigations as well as data from literature are presented to the problem of the harmonization of the cholesterol determination with the precipitation technique. According to the opinion of the authors for the enzymatic determination of cholesterol by means of the CHOD-PAP-method the phosphotungstic acid precipitation well stood the test, whereas for the chemical determination of cholesterol after Liebermann-Burchard in manual or automatized works the precipitation by means of dextran sulphate/CaCl2 (40 g/l, 2.0 mol/l) is to be recommended. The superabundant precipitations with phosphotungstic acid and dextran sulphate/MgCl2 (20 g/l, 2.0 mol/l) achieve higher results in Liebermann-Burchard's reaction likely on account of interferences.

  20. A Predictive Framework for Determining How Journalists Determine News.

    ERIC Educational Resources Information Center

    Gaudino, James L.

    To determine how to articulate a concrete definition of the substance of the journalist's occupation, this paper offers a propositional framework of news value based on Kurt Lewin's gatekeeper model. First, the paper follows the established suggestion that news decisions are best studied from a gatekeeping perspective or that "news is…

  1. Determination of radium in water

    USGS Publications Warehouse

    Barker, Franklin Butt; Johnson, J.O.

    1964-01-01

    Radium isotopes are common radioactive constituents of natural waters. The concentration of radium-226 in potable water is of particular significance because this isotope is generally considered the most hazardous of all radionuclides with respect to ingestion. The approximate concentration of radium-226 is determined after coprecipitating radium with barium sulfate. The short-lived daughters of radium are allowed to grow for 10-12 days, then the alpha activity of the precipitate is measured and compared with that of a precipitate containing a known amount of radium-226. Concentrations of the individual alpha-emitting isotopes of radium-223, radium-224, and radium-226, are determined by coprecipitating radium first with lead sulfate, then with barium chloride, and finally with barium sulfate. This final precipitate is initially free of other alpha-emitting nuclides, thus permitting the isotopic composition to be determined by measuring the growth and decay of the alpha activity of the precipitate.

  2. Spherical Dirac GJMS operator determinants

    NASA Astrophysics Data System (ADS)

    Dowker, J. S.

    2015-01-01

    Motivated by AdS/CFT, the extension is made to spin-half of a scalar calculation of the conformal anomalies and functional determinants of GJMS operators on spheres. The formal aspects are heuristic but sufficient. A Barnes zeta-function representation again proves effective. The determinants are calculated for the two factorizations of the general Γ-function (intertwiner) form of the GJMS operator, and shown to be equal, even including any multiplicative anomaly. A comment is made on the general eigenvalue problem and a few numerical results are presented. An alternative approach is detailed for odd dimensions and it is shown that the scalar determinants are expressed in terms of the spinor ones, and vice versa. An explicit, general form is given.

  3. Lessons for inductive germline determination.

    PubMed

    Seervai, Riyad N H; Wessel, Gary M

    2013-08-01

    Formation of the germline in an embryo marks a fresh round of reproductive potential, yet the developmental stage and location within the embryo where the primordial germ cells (PGCs) form differs wildly among species. In most animals, the germline is formed either by an inherited mechanism, in which maternal provisions within the oocyte drive localized germ-cell fate once acquired in the embryo, or an inductive mechanism that involves signaling between cells that directs germ-cell fate. The inherited mechanism has been widely studied in model organisms such as Drosophila melanogaster, Caenorhabditis elegans, Xenopus laevis, and Danio rerio. Given the rapid generation time and the effective adaptation for laboratory research of these organisms, it is not coincidental that research on these organisms has led the field in elucidating mechanisms for germline specification. The inductive mechanism, however, is less well understood and is studied primarily in the mouse (Mus musculus). In this review, we compare and contrast these two fundamental mechanisms for germline determination, beginning with the key molecular determinants that play a role in the formation of germ cells across all animal taxa. We next explore the current understanding of the inductive mechanism of germ-cell determination in mice, and evaluate the hypotheses for selective pressures on these contrasting mechanisms. We then discuss the hypothesis that the transition between these determination mechanisms, which has happened many times in phylogeny, is more of a continuum than a binary change. Finally, we propose an analogy between germline determination and sex determination in vertebrates-two of the milestones of reproduction and development-in which animals use contrasting strategies to activate similar pathways.

  4. Lessons for Inductive Germline Determination

    PubMed Central

    Seervai, Riyad N.H.; Wessel, Gary M.

    2015-01-01

    SUMMARY Formation of the germline in an embryo marks a fresh round of reproductive potential, yet the developmental stage and location within the embryo where the primordial germ cells (PGCs) form differs wildly among species. In most animals, the germline is formed either by an inherited mechanism, in which maternal provisions within the oocyte drive localized germ-cell fate once acquired in the embryo, or an inductive mechanism that involves signaling between cells that directs germ-cell fate. The inherited mechanism has been widely studied in model organisms such as Drosophila melanogaster, Caenorhabditis elegans, Xenopus laevis, and Danio rerio. Given the rapid generation time and the effective adaptation for laboratory research of these organisms, it is not coincidental that research on these organisms has led the field in elucidating mechanisms for germline specification. The inductive mechanism, however, is less well understood and is studied primarily in the mouse (Mus musculus). In this review, we compare and contrast these two fundamental mechanisms for germline determination, beginning with the key molecular determinants that play a role in the formation of germ cells across all animal taxa. We next explore the current understanding of the inductive mechanism of germ-cell determination in mice, and evaluate the hypotheses for selective pressures on these contrasting mechanisms. We then discuss the hypothesis that the transition between these determination mechanisms, which has happened many times in phylogeny, is more of a continuum than a binary change. Finally, we propose an analogy between germline determination and sex determination in vertebrates—two of the milestones of reproduction and development—in which animals use contrasting strategies to activate similar pathways. PMID:23450642

  5. MEANS FOR DETERMINING CENTRIFUGE ALIGNMENT

    DOEpatents

    Smith, W.Q.

    1958-08-26

    An apparatus is presented for remotely determining the alignment of a centrifuge. The centrifage shaft is provided with a shoulder, upon which two followers ride, one for detecting radial movements, and one upon the shoulder face for determining the axial motion. The followers are attached to separate liquid filled bellows, and a tube connects each bellows to its respective indicating gage at a remote location. Vibrations produced by misalignment of the centrifuge shaft are transmitted to the bellows, and tbence through the tubing to the indicator gage. This apparatus is particularly useful for operation in a hot cell where the materials handled are dangerous to the operating personnel.

  6. Decoherence, determinism and chaos revisited

    SciTech Connect

    Noyes, H.P.

    1994-11-15

    We suggest that the derivation of the free space Maxwell Equations for classical electromagnetism, using a discrete ordered calculus developed by L.H. Kauffman and T. Etter, necessarily pushes the discussion of determinism in natural science down to the level of relativistic quantum mechanics and hence renders the mathematical phenomena studied in deterministic chaos research irrelevant to the question of whether the world investigated by physics is deterministic. We believe that this argument reinforces Suppes` contention that the issue of determinism versus indeterminism should be viewed as a Kantian antinomy incapable of investigation using currently available scientific tools.

  7. Determinate-state convolutional codes

    NASA Technical Reports Server (NTRS)

    Collins, O.; Hizlan, M.

    1991-01-01

    A determinate state convolutional code is formed from a conventional convolutional code by pruning away some of the possible state transitions in the decoding trellis. The type of staged power transfer used in determinate state convolutional codes proves to be an extremely efficient way of enhancing the performance of a concatenated coding system. The decoder complexity is analyzed along with free distances of these new codes and extensive simulation results is provided of their performance at the low signal to noise ratios where a real communication system would operate. Concise, practical examples are provided.

  8. Relationships between Arachidonic Acid, Uterine Activity and Metabolic Regulation of Placental Lactogen Secretion.

    DTIC Science & Technology

    1982-08-01

    variations and to determine the metabolic role of oPL during gestation. Fasting, which decreased plasma glucose and increased plasma free fatty acid ... fatty acids induced by fasting or to have diabetogenic effects. The intravenous administration of 12.5 or 25 mg of arachidonic acid resulted in a...of hPL is thought to be controlled by the plasma con- centrations of the metabolic substrates; carbohydrate, fat or protein. Plasma free fatty acid

  9. Sex determination using maxillary sinus

    PubMed Central

    Kanthem, Ranjith Kumar; Guttikonda, Venkateswara Rao; Yeluri, Sivaranjani; Kumari, Geetha

    2015-01-01

    Background: Individual identification is a subtle concept and often one of the most important priorities in mass disasters, road accidents, air crashes, fires, and even in the investigation of criminal cases. Matching specific features detected on the cadaver with data recorded during the life of an individual is an important aspect in forensics, and can be performed by fingerprint analysis, deoxyribonucleic acid matching, anthropological methods, radiological methods and other techniques which can facilitate age and sex identification. Sinus radiography is one such method that has been used for determination of the sex of an individual. Hence, an attempt is being made to use the different dimensions of the maxillary sinus in the determination of sex using coronal and axial sections of plain computed tomography (CT) scan. Materials and Methods: A total of 30 patients including 17 male and 13 female, visiting the Outpatient Department of the Mamata General Hospital were included as the study subjects. The dimensions of right and left maxillary sinuses of 30 subjects from plain CT were measured using SYNGO software and statistical analysis was done. Results: Sex determination using height, length, width, and volume of the maxillary sinus on both sides showed statistically significant results with a higher percentage of sexual dimorphism in the case of volume. Conclusion: Volume of the right maxillary sinus can be used as accurate diagnostic parameter for sex determination. PMID:26005308

  10. Determining Salinity by Simple Means.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    This paper describes the construction and use of a simple salinometer. The salinometer is composed, mainly, of a milliammeter and a battery and uses the measurement of current flow to determine the salinity of water. A complete list of materials is given, as are details of construction and operation of the equipment. The use of the salinometer in…

  11. Videos Determine the Moon's "g"

    ERIC Educational Resources Information Center

    Persson, J. R.; Hagen, J. E.

    2011-01-01

    Determining the acceleration of a free-falling object due to gravity is a standard experiment in physics. Different methods to do this have been developed over the years. This article discusses the use of video-analysis tools as another method. If there is a video available and a known scale it is possible to analyse the motion. The use of video…

  12. Self-Determination: First Steps.

    ERIC Educational Resources Information Center

    Thompson, Morris

    The year 1974 marked the first full year in which the Bureau of Indian Affairs (BIA) officially embarked on a policy of advising and assisting American Indian tribes to assume the administration of their own affairs (self-determination). It seeks to strengthen and stabilize tribal governments while continuing to maintain and fulfill its trust…

  13. Cesium Eluate Physical Property Determination

    SciTech Connect

    Baich, M.A.

    2001-02-13

    Two bench-scale process simulations of the proposed cesium eluate evaporation process of concentrating eluate produced in the Hanford Site Waste Treatment Plant were conducted. The primary objective of these experiments was to determine the physical properties and the saturation concentration of the eluate evaporator bottoms while producing condensate approximately 0.50 molar HN03.

  14. Time domain period determination techniques

    NASA Technical Reports Server (NTRS)

    Stellingwerf, R. F.

    1980-01-01

    Two simple period determination schemes are discussed. They are well suited to problems involving non-sinusoidal periodic phenomena sampled at a few irregularly spaced points. Statistical properties are discussed. The techniques are applied to the double mode Cepheids BK Cen and TU Cas as test cases.

  15. Self-Determination and Bilingualism

    ERIC Educational Resources Information Center

    Landry, Rodrigue; Allard, Real; Deveau, Kenneth

    2009-01-01

    This article focuses on additive bilingualism for minority group children, more specifically the development of strong literacy skills in English and in the children's language. The personal autonomization language learning (PALL) model is presented. It specifies eight testable hypotheses. Self-determination theory (SDT) is central in the PALL…

  16. Cohesin in determining chromosome architecture

    SciTech Connect

    Haering, Christian H.; Jessberger, Rolf

    2012-07-15

    Cells use ring-like structured protein complexes for various tasks in DNA dynamics. The tripartite cohesin ring is particularly suited to determine chromosome architecture, for it is large and dynamic, may acquire different forms, and is involved in several distinct nuclear processes. This review focuses on cohesin's role in structuring chromosomes during mitotic and meiotic cell divisions and during interphase.

  17. Determining Learning Disabilities in Mathematics.

    ERIC Educational Resources Information Center

    Dunlap, William P.; And Others

    1979-01-01

    To determine the generalizability of reading expectancy formulas in ascertaining mathematics expectancy levels, correlation coefficients were computed between the scores of 150 Ss (7 to 12 years old) with learning problems on standardized mathematics and reading tests and expectancy scores. Formulas correlated higher with Ss' actual mathematics…

  18. Determination of nominal accelerating potential

    SciTech Connect

    Nizin, P.; Kase, K.

    1986-11-01

    We present a simple linear relationship between the nominal accelerating potential (NAP) and the ratios of ionization measurements made with constant source--detector distance and at two different phantom thicknesses. This relationship can be used as a standard, unambiguous method for determining NAP for use in dosimetry and quality control.

  19. Plasma digital density determining device

    DOEpatents

    Sprott, Julien C.; Lovell, Thomas W.; Holly, Donald J.

    1976-01-01

    The density of a decaying plasma in an electrically conducting enclosure is determined by applying an excitation to the cavity formed by the enclosure and counting digitally the number of resonant frequencies traversed by the combination of the cavity and the decaying plasma.

  20. Time domain period determination techniques

    NASA Astrophysics Data System (ADS)

    Stellingwerf, R. F.

    1980-05-01

    Two simple period determination schemes are discussed. They are well suited to problems involving non-sinusoidal periodic phenomena sampled at a few irregularly spaced points. Statistical properties are discussed. The techniques are applied to the double mode Cepheids BK Cen and TU Cas as test cases.

  1. Transcriptional enhancer within the human placental lactogen and growth hormone multigene cluster.

    PubMed Central

    Rogers, B L; Sobnosky, M G; Saunders, G F

    1986-01-01

    Human placental lactogen (hPL) and human growth hormone (hGH) are members of a multigene family that share amino acid sequence homology and similarity in gene structure and nucleotide sequence, but differ in both function and expression. To determine the sequence requirements for tissue specific expression recombinant plasmids containing the members of the hPL-hGH multigene family and flanking regions were analyzed by both transient and stable transfection assays. We have identified a transcriptional enhancer in a 1.0 kb region located 2.0 kb downstream of the hPL3 structural gene. This enhancer sequence is not strictly cell-type specific since it functions in cell lines of both placental (JEG-3) and pituitary (18-54,SF) origin. However, its efficiency is several fold higher in placental cells than in pituitary cells. Images PMID:3774541

  2. Immunobiological determinants in organ transplantation.

    PubMed Central

    Marks, C.

    1983-01-01

    The most important development in determining successful organ transplantation has been the improved understanding of the immune response and the interactions between antigens, antibody, immune complexes, complement component, lymphocytes and macrophages. The initiation and termination of an immune response, whether cellular or humoral depends upon cellular interaction between subsets of the lymphocyte cell series and macrophages. An equilibrium between helper and suppressor T cells determines protection of the host from non-self tissue invasion, infection and neoplasia. The role of mediators, immunosuppressants, hybridomas and recombitant DNA technology are briefly considered. The relative importance of tissue typing and blood transfusion in preventing allograft rejection is considered and the role of immunological monitoring in allograft transplantation is reviewed. PMID:6344730

  3. Low thrust orbit determination program

    NASA Technical Reports Server (NTRS)

    Hong, P. E.; Shults, G. L.; Huling, K. R.; Ratliff, C. W.

    1972-01-01

    Logical flow and guidelines are provided for the construction of a low thrust orbit determination computer program. The program, tentatively called FRACAS (filter response analysis for continuously accelerating spacecraft), is capable of generating a reference low thrust trajectory, performing a linear covariance analysis of guidance and navigation processes, and analyzing trajectory nonlinearities in Monte Carlo fashion. The choice of trajectory, guidance and navigation models has been made after extensive literature surveys and investigation of previous software. A key part of program design relied upon experience gained in developing and using Martin Marietta Aerospace programs: TOPSEP (Targeting/Optimization for Solar Electric Propulsion), GODSEP (Guidance and Orbit Determination for SEP) and SIMSEP (Simulation of SEP).

  4. Genetic determinants of glucose homeostasis.

    PubMed

    Barker, Adam; Langenberg, Claudia; Wareham, Nicholas J

    2012-04-01

    Type 2 diabetes is a complex metabolic disorder characterised by varying degrees of impairment in insulin secretion and resistance to the action of insulin. Considerable progress has been made recently in understanding the genetic determinants of diabetes. A logical next step is to describe how these variants relate to the underlying pathophysiological processes that lead to diabetes as this may provide insights into pathways to disease. These quantitative traits are, of course, of direct interest in themselves and a growing literature is now emerging on the genetic determinants of insulin secretion and insulin resistance. This review article focuses on describing the complex associations between type 2 diabetes risk variants and quantitative glycaemic traits and the relationship between variants initially discovered in association studies of these traits and risk of type 2 diabetes.

  5. [Determination of aflatoxins in cheeses].

    PubMed

    Bartos, J; Matyás, Z

    1979-03-01

    To investigate cheeses for the presence of aflatoxins we chose the very sensitive method of Tuinstra and Bronsgeest (1975) used for the determination of aflatoxin M1 in milk. The method was slightly modified and the presence of aflatoxins was determined in 54 samples of different cheeses. Aflatoxin M1 was found out in 24% of the investigated samples. Most of positive samples were found among the soft cheeses (53.8 3/4), then in processed cheeses (13.6%) and in hard cheeses (12.5%). Aflatoxin M1 was not found in the group of mouldy cheeses and Olomouc cake cheeses, which were investigated in a smaller range. Positive findings did not exceed concentrations of 10 ng per kg, i.e. they did not even reach the value of permissible concentration as proposed in the Czech Socialist Republic for foods (5 microgram per kg).

  6. System for determining aerodynamic imbalance

    NASA Technical Reports Server (NTRS)

    Churchill, Gary B. (Inventor); Cheung, Benny K. (Inventor)

    1994-01-01

    A system is provided for determining tracking error in a propeller or rotor driven aircraft by determining differences in the aerodynamic loading on the propeller or rotor blades of the aircraft. The system includes a microphone disposed relative to the blades during the rotation thereof so as to receive separate pressure pulses produced by each of the blades during the passage thereof by the microphone. A low pass filter filters the output signal produced by the microphone, the low pass filter having an upper cut-off frequency set below the frequency at which the blades pass by the microphone. A sensor produces an output signal after each complete revolution of the blades, and a recording display device displays the outputs of the low pass filter and sensor so as to enable evaluation of the relative magnitudes of the pressure pulses produced by passage of the blades by the microphone during each complete revolution of the blades.

  7. Cytokine determinants of viral tropism.

    PubMed

    McFadden, Grant; Mohamed, Mohamed R; Rahman, Masmudur M; Bartee, Eric

    2009-09-01

    The specificity of a given virus for a cell type, tissue or species - collectively known as viral tropism - is an important factor in determining the outcome of viral infection in any particular host. Owing to the increased prevalence of zoonotic infections and the threat of emerging and re-emerging pathogens, gaining a better understanding of the factors that determine viral tropism has become particularly important. In this Review, we summarize our current understanding of the central role of antiviral and pro-inflammatory cytokines, particularly the interferons and tumour necrosis factor, in dictating viral tropism and how these cytokine pathways can be exploited therapeutically for cancer treatment and to better counter future threats from emerging zoonotic pathogens.

  8. Means of determining extrusion temperatures

    DOEpatents

    McDonald, Robert E.; Canonico, Domenic A.

    1977-01-01

    In an extrusion process comprising the steps of fabricating a metal billet, heating said billet for a predetermined time and at a selected temperature to increase its plasticity and then forcing said heated billet through a small orifice to produce a desired extruded object, the improvement comprising the steps of randomly inserting a plurality of small metallic thermal tabs at different cross sectional depths in said billet as a part of said fabricating step, and examining said extruded object at each thermal tab location for determining the crystal structure at each extruded thermal tab thus revealing the maximum temperature reached during extrusion in each respective tab location section of the extruded object, whereby the thermal profile of said extruded object during extrusion may be determined.

  9. Range determination for scannerless imaging

    DOEpatents

    Muguira, Maritza Rosa; Sackos, John Theodore; Bradley, Bart Davis; Nellums, Robert

    2000-01-01

    A new method of operating a scannerless range imaging system (e.g., a scannerless laser radar) has been developed. This method is designed to compensate for nonlinear effects which appear in many real-world components. The system operates by determining the phase shift of the laser modulation, which is a physical quantity related physically to the path length between the laser source and the detector, for each pixel of an image.

  10. System for determining biofuel concentration

    DOEpatents

    Huff, Shean P.; Janke, Christopher James; Kass, Michael D.; Lewis, Sr, Samuel Arthur; Pawel, Steven J; Theiss, Timothy J.

    2016-09-13

    A measurement device or system configured to measure the content of biofuels within a fuel blend. By measuring a state of a responsive material within a fuel blend, a biofuel content of the fuel blend may be measured. For example, the solubility of a responsive material to biofuel content within a fuel blend, may affect a property of the responsive material, such as shape, dimensional size, or electrical impedance, which may be measured and used as a basis for determining biofuel content.

  11. Method for determining gene knockouts

    DOEpatents

    Maranas, Costas D.; Burgard, Anthony R.; Pharkya, Priti

    2011-09-27

    A method for determining candidates for gene deletions and additions using a model of a metabolic network associated with an organism, the model includes a plurality of metabolic reactions defining metabolite relationships, the method includes selecting a bioengineering objective for the organism, selecting at least one cellular objective, forming an optimization problem that couples the at least one cellular objective with the bioengineering objective, and solving the optimization problem to yield at least one candidate.

  12. Method for determining gene knockouts

    DOEpatents

    Maranas, Costa D; Burgard, Anthony R; Pharkya, Priti

    2013-06-04

    A method for determining candidates for gene deletions and additions using a model of a metabolic network associated with an organism, the model includes a plurality of metabolic reactions defining metabolite relationships, the method includes selecting a bioengineering objective for the organism, selecting at least one cellular objective, forming an optimization problem that couples the at least one cellular objective with the bioengineering objective, and solving the optimization problem to yield at least one candidate.

  13. In-flight thrust determination

    NASA Technical Reports Server (NTRS)

    Abernethy, Robert B.; Adams, Gary R.; Ascough, John C.; Baer-Riedhart, Jennifer L.; Balkcom, George H.; Biesiadny, Thomas

    1986-01-01

    The major aspects of processes that may be used for the determination of in-flight thrust are reviewed. Basic definitions are presented as well as analytical and ground-test methods for gathering data and calculating the thrust of the propulsion system during the flight development program of the aircraft. Test analysis examples include a single-exhaust turbofan, an intermediate-cowl turbofan, and a mixed-flow afterburning turbofan.

  14. Rate determination from vector observations

    NASA Technical Reports Server (NTRS)

    Weiss, Jerold L.

    1993-01-01

    Vector observations are a common class of attitude data provided by a wide variety of attitude sensors. Attitude determination from vector observations is a well-understood process and numerous algorithms such as the TRIAD algorithm exist. These algorithms require measurement of the line of site (LOS) vector to reference objects and knowledge of the LOS directions in some predetermined reference frame. Once attitude is determined, it is a simple matter to synthesize vehicle rate using some form of lead-lag filter, and then, use it for vehicle stabilization. Many situations arise, however, in which rate knowledge is required but knowledge of the nominal LOS directions are not available. This paper presents two methods for determining spacecraft angular rates from vector observations without a priori knowledge of the vector directions. The first approach uses an extended Kalman filter with a spacecraft dynamic model and a kinematic model representing the motion of the observed LOS vectors. The second approach uses a 'differential' TRIAD algorithm to compute the incremental direction cosine matrix, from which vehicle rate is then derived.

  15. Spectrophotometric determination of phosphorus acid

    SciTech Connect

    Domin, A.V.; Domina, N.G.; Zakharov, Yu.A.; Shechkov, G.T.

    1987-03-01

    A number of procedures have been proposed to determine phosphorus acid and its salts, the phosphites, in the presence of hypophosphorus acid and its salts, the hypophosphites. Among these procedures, iodometric back-titration has produced the most reliable results. In this paper, the authors propose an improved iodometric determination of phosphorus acid that enables the sensitivity to be increased by at least two orders of magnitude. The essence of this improvement is that excess iodine that did not react with phosphite ion is determined not volumetrically but spectrophotometrically. To eliminate the effect of iodine ion that is liberated when iodine reacts with phosphite ion on the optical density of the solution, a 200-fold excess of potassium iodide is added before the photometric measurement. The working iodine solution is prepared by diluting 10 m of 0.025 N iodine titrant and 50 ml of phosphate buffer, pH 6.7-7.2, to 1 liter with distilled water in a coulometric flask. To construct the calibration curve, 5, 10, 15, 20, and 25 ml, respectively of working iodine solution, and 10 ml of 2% aqueous potassium iodide are placed into five 100-ml volumetric flasks, and the solutions are made up to volume with water. After 10 min the photometric measurements are carried out at 380 nm using curvets and the reference solution is obtained by diluting 10 ml of 2% aqueous potassium iodide to 100 ml with distilled water.

  16. [Monitoring social determinants of health].

    PubMed

    Espelt, Albert; Continente, Xavier; Domingo-Salvany, Antonia; Domínguez-Berjón, M Felicitas; Fernández-Villa, Tania; Monge, Susana; Ruiz-Cantero, M Teresa; Perez, Glòria; Borrell, Carme

    2016-11-01

    Public health surveillance is the systematic and continuous collection, analysis, dissemination and interpretation of health-related data for planning, implementation and evaluation of public health initiatives. Apart from the health system, social determinants of health include the circumstances in which people are born, grow up, live, work and age, and they go a long way to explaining health inequalities. A surveillance system of the social determinants of health requires a comprehensive and social overview of health. This paper analyses the importance of monitoring social determinants of health and health inequalities, and describes some relevant aspects concerning the implementation of surveillance during the data collection, compilation and analysis phases, as well as dissemination of information and evaluation of the surveillance system. It is important to have indicators from sources designed for this purpose, such as continuous records or periodic surveys, explicitly describing its limitations and strengths. The results should be published periodically in a communicative format that both enhances the public's ability to understand the problems that affect them, whilst at the same time empowering the population, with the ultimate goal of guiding health-related initiatives at different levels of intervention.

  17. Determination of human chorionic gonadotropin.

    PubMed

    Stenman, Ulf-Håkan; Alfthan, Henrik

    2013-12-01

    Determination of human chorionic gonadotropin (hCG) is used for diagnosis and monitoring of pregnancy, pregnancy related disorders, for trophoblastic and some nontrophoblastic tumors. In addition, hCG is determined for doping control in males. Assay of hCG is complicated by the occurrence of different molecular forms, which are detected to various degrees by different assays. The main form of hCG in circulation and in patients with trophoblastic tumors is intact heterodimeric hCG. The free β subunit (hCGβ) is a minor form in plasma in both conditions, but it may be the major form aggressive trophoblastic cancer. Therefore, assays measuring hCG and hCGβ together are mainly used for diagnosis of pregnancy and trophoblastic diseases. When excreted into urine, most of hCG (and hCGβ) is broken down to the core fragment of hCGβ (hCGβcf), which is the main immunoreactive form of hCG in urine during pregnancy. Specific determination of hCGβ is of value in screening for Down's syndrome and diagnosis of nontrophoblastic cancer. hCGbcf is of limited utility but it is important because it may disturb assay of hCG in pregnancy.

  18. Efficient, sparse biological network determination

    PubMed Central

    August, Elias; Papachristodoulou, Antonis

    2009-01-01

    Background Determining the interaction topology of biological systems is a topic that currently attracts significant research interest. Typical models for such systems take the form of differential equations that involve polynomial and rational functions. Such nonlinear models make the problem of determining the connectivity of biochemical networks from time-series experimental data much harder. The use of linear dynamics and linearization techniques that have been proposed in the past can circumvent this, but the general problem of developing efficient algorithms for models that provide more accurate system descriptions remains open. Results We present a network determination algorithm that can treat model descriptions with polynomial and rational functions and which does not make use of linearization. For this purpose, we make use of the observation that biochemical networks are in general 'sparse' and minimize the 1-norm of the decision variables (sum of weighted network connections) while constraints keep the error between data and the network dynamics small. The emphasis of our methodology is on determining the interconnection topology rather than the specific reaction constants and it takes into account the necessary properties that a chemical reaction network should have – something that techniques based on linearization can not. The problem can be formulated as a Linear Program, a convex optimization problem, for which efficient algorithms are available that can treat large data sets efficiently and uncertainties in data or model parameters. Conclusion The presented methodology is able to predict with accuracy and efficiency the connectivity structure of a chemical reaction network with mass action kinetics and of a gene regulatory network from simulation data even if the dynamics of these systems are non-polynomial (rational) and uncertainties in the data are taken into account. It also produces a network structure that can explain the real experimental

  19. Soil carbon determination by thermogravimetrics

    PubMed Central

    Pallasser, Robert; McBratney, Alex B.

    2013-01-01

    Determination of soil constituents and structure has a vital role in agriculture generally. Methods for the determination of soil carbon have in particular gained greater currency in recent times because of the potential that soils offer in providing offsets for greenhouse gas (CO2-equivalent) emissions. Ideally, soil carbon which can also be quite diverse in its makeup and origin, should be measureable by readily accessible, affordable and reliable means. Loss-on-ignition is still a widely used method being suitably simple and available but may have limitations for soil C monitoring. How can these limitations be better defined and understood where such a method is required to detect relatively small changes during soil-C building? Thermogravimetric (TGA) instrumentation to measure carbonaceous components has become more interesting because of its potential to separate carbon and other components using very precise and variable heating programs. TGA related studies were undertaken to assist our understanding in the quantification of soil carbon when using methods such as loss-on-ignition. Combining instrumentation so that mass changes can be monitored by mass spectrometer ion currents has elucidated otherwise hidden features of thermal methods enabling the interpretation and evaluation of mass-loss patterns. Soil thermogravimetric work has indicated that loss-on-ignition methods are best constrained to temperatures from 200 to 430 °C for reliable determination for soil organic carbon especially where clay content is higher. In the absence of C-specific detection where mass only changes are relied upon, exceeding this temperature incurs increasing contributions from inorganic sources adding to mass losses with diminishing contributions related to organic matter. The smaller amounts of probably more recalcitrant organic matter released at the higher temperatures may represent mineral associated material and/or simply more refractory forms. PMID:23638398

  20. Dietary Determinants of Prostate Cancer

    DTIC Science & Technology

    2005-03-01

    no additional Genistein or SIT and omega FA ratio of 48 omega- 6:1 omega - 3 ), FA ratio of 25 omega-6: 1 omega - 3 , 1% SIT, or 0.02% Genistein diets. This...was done to determine if the test compounds will affect the implantation of the tumor cells. In addition, omega FA ratios of omega-6: omega - 3 for the...FA test diet needed to be reduced (as opposed to increased as originally planned) due to the high omega-6: omega - 3 ratio of the control diet (as in

  1. Determination of triclosan in foodstuffs.

    PubMed

    Sanches-Silva, Ana; Sendón-García, Raquel; López-Hernández, Julia; Paseiro-Losada, Perfecto

    2005-01-01

    A reverse-phase high-performance liquid chromatographic (RP-HPLC) method coupled with an ultraviolet detector was developed to determine triclosan which had migrated into foodstuffs from packaging materials. The method includes extraction with hexane, followed by evaporation to dryness and residue re-dissolution in ACN 90%. Chromatographic separation was performed with a Kromasil 100 C18 column (15 cm x 0.4 cm ID, 5 microm particle size) at 30 degrees C and using ACN and water as mobile phases. Regarding recoveries, good results (higher than 83% and lower than 112%) were obtained for the three representative food matrixes selected (orange juice, chicken breast meat, and Gouda cheese).

  2. Structure determination of enterovirus 71

    SciTech Connect

    Plevka, Pavel; Perera, Rushika; Cardosa, Jane; Kuhn, Richard J.; Rossmann, Michael G.

    2013-02-20

    Enterovirus 71 is a picornavirus that causes hand, foot and mouth disease but may induce fatal neurological illness in infants and young children. Enterovirus 71 crystallized in a body-centered orthorhombic space group with two particles in general orientations in the crystallographic asymmetric unit. Determination of the particle orientations required that the locked rotation function excluded the twofold symmetry axes from the set of icosahedral symmetry operators. This avoided the occurrence of misleading high rotation-function values produced by the alignment of icosahedral and crystallographic twofold axes. Once the orientations and positions of the particles had been established, the structure was solved by molecular replacement and phase extension.

  3. Genetic modification and genetic determinism.

    PubMed

    Resnik, David B; Vorhaus, Daniel B

    2006-06-26

    In this article we examine four objections to the genetic modification of human beings: the freedom argument, the giftedness argument, the authenticity argument, and the uniqueness argument. We then demonstrate that each of these arguments against genetic modification assumes a strong version of genetic determinism. Since these strong deterministic assumptions are false, the arguments against genetic modification, which assume and depend upon these assumptions, are therefore unsound. Serious discussion of the morality of genetic modification, and the development of sound science policy, should be driven by arguments that address the actual consequences of genetic modification for individuals and society, not by ones propped up by false or misleading biological assumptions.

  4. Determinants of internet poker adoption.

    PubMed

    Philander, Kahlil S; Abarbanel, B Lillian

    2014-09-01

    In nearly all jurisdictions, adoption of a new form of gambling has been a controversial and contentious subject. Online gambling has been no different, though there are many aspects that affect online gambling that do not appear in the brick and mortar environment. This study seeks to identify whether demographic, economic, political, technological, and/or sociological determinants contribute to online poker gambling adoption. A theoretical discussion of these categories' importance to online poker is provided and exploratory empirical analysis is used to examine their potential validity. The analysis revealed support for all of the proposed categories of variables thought to be predictive of online gambling legality.

  5. Determination of pigments in vegetables.

    PubMed

    Schoefs, Benoît

    2004-10-29

    Plant pigments are responsible for the shining color of plant tissues. They are also found in animal tissues and, eventually in transformed food products as additives. These pigments have an important impact on the commercial value of products, because the colors establish the first contact with the consumer. In addition plant pigments may have an influence on the health of the consumers. Pigments are labile: they can be easily altered, and even destroyed. Analytical processes have been developed to determine pigment composition. The aim of this paper is to provide a brief overview of these methods.

  6. SOP - Determination of Requirement Density

    SciTech Connect

    Reynolds, John G.; Martz, Jr., Harry E.

    2010-10-26

    The purpose of this Standard Operating Procedure (SOP) is to give guidelines on how to determine the density of a sample that will be used as the requirement density. This will be the requirement density of record for the specimens examined by Micro CT and EDS measurements. This density will then be set as the formulation requirement for radiography measurements. This SOP is referred to in TP 48— Preparation of Hydrogen Peroxide/Icing Sugar Specimens for X-ray Measurements by J. G. Reynolds and H. E. Martz.

  7. Method for determining astronomic azimuth

    NASA Astrophysics Data System (ADS)

    Evans, Alan G.; Stein, William L.

    1990-09-01

    An improved method is disclosed for fixing position of a land based target site with respect to a reference site in the natural coordinate frame comprising the steps of determining geodetic azimuth between the target site and the reference target using Global Positioning System (GPS) satellites and relative positioning survey techniques; then calculating a relationship using gravity vertical deflections; and then converting the geodetic azimuth to astronomic azimuth. This method has several advantages over conventional methods of targeting, including speed, the ability to work in all weather conditions, and improved accuracy.

  8. Determinants of fertility in Guatemala.

    PubMed

    Anderson, J E; Morris, L; Pineda, A; Santiso, R

    1980-01-01

    The 1978 Contraceptive Prevalence Survey for Guatemala provides an opportunity to examine fertility levels and a number of determinants of fertility for three broad segments of the country: the Department of Guatemala and, in the remainder of the country, the Ladino and Indian populations. While Ladinos had a much higher rate of contraceptive use than did Indians, the two groups had similar birth rates. The lack of difference in fertility appears to be due to the pattern of prolonged breastfeeding among Indians and perhaps to differences in the rate of conception due to nutrition, coital frequency, or other factors.

  9. Genetic modification and genetic determinism

    PubMed Central

    Resnik, David B; Vorhaus, Daniel B

    2006-01-01

    In this article we examine four objections to the genetic modification of human beings: the freedom argument, the giftedness argument, the authenticity argument, and the uniqueness argument. We then demonstrate that each of these arguments against genetic modification assumes a strong version of genetic determinism. Since these strong deterministic assumptions are false, the arguments against genetic modification, which assume and depend upon these assumptions, are therefore unsound. Serious discussion of the morality of genetic modification, and the development of sound science policy, should be driven by arguments that address the actual consequences of genetic modification for individuals and society, not by ones propped up by false or misleading biological assumptions. PMID:16800884

  10. Determination of uranium in zircon

    USGS Publications Warehouse

    Cuttitta, F.; Daniels, G.J.

    1959-01-01

    A routine fluorimetric procedure is described for the determination of trace amounts of uranium in zircon. It employs the direct extraction of uranyl nitrate with ethyl acetate using phosphate as a retainer for zirconium. Submicrogram amounts or uranium are separated in the presence of 100,000 times the amount of zirconium. The modified procedure has been worked out using synthetic mixtures of known composition and zircon. Results of analyses have an accuracy of 97-98% of the contained uranium and a standard deviation of less than 2.5%. ?? 1959.

  11. Medical Qualification Determinations. Final rule.

    PubMed

    2017-01-18

    The U.S. Office of Personnel Management (OPM) is issuing a final rule to revise its regulations for medical qualification determinations. The revised regulations update references and language; add and modify definitions; clarify coverage and applicability; address the need for medical documentation and medical examination and/or testing for an applicant or employee whose position may or may not have medical standards and/or physical requirements; and recommend the establishment of agency medical review boards. The final rule provides agencies guidance regarding medical evaluation procedures.

  12. Crystal face temperature determination means

    DOEpatents

    Nason, D.O.; Burger, A.

    1994-11-22

    An optically transparent furnace having a detection apparatus with a pedestal enclosed in an evacuated ampule for growing a crystal thereon is disclosed. Temperature differential is provided by a source heater, a base heater and a cold finger such that material migrates from a polycrystalline source material to grow the crystal. A quartz halogen lamp projects a collimated beam onto the crystal and a reflected beam is analyzed by a double monochromator and photomultiplier detection spectrometer and the detected peak position in the reflected energy spectrum of the reflected beam is interpreted to determine surface temperature of the crystal. 3 figs.

  13. Liquid chromatographic determination of water

    DOEpatents

    Fortier, Nancy E.; Fritz, James S.

    1990-11-13

    A sensitive method for the determination of water in the presence of common interferences is presented. The detection system is based on the effect of water on the equilibrium which results from the reaction aryl aldehydes, such as cinnamaldehyde and methanol in the eluent to form cinnamaldehyde dimethylacetal, plus water. This equilibrium is shifted in a catalytic atmosphere of a hydrogen ion form past column reactor. The extent of the shift and the resulting change in absorbance are proportional to the amount of water present.

  14. Liquid chromatographic determination of water

    DOEpatents

    Fortier, N.E.; Fritz, J.S.

    1990-11-13

    A sensitive method for the determination of water in the presence of common interferences is presented. The detection system is based on the effect of water on the equilibrium which results from the reaction aryl aldehydes, such as cinnamaldehyde and methanol in the eluent to form cinnamaldehyde dimethylacetal, plus water. This equilibrium is shifted in a catalytic atmosphere of a hydrogen ion form past column reactor. The extent of the shift and the resulting change in absorbance are proportional to the amount of water present. 1 fig.

  15. Sry, more than testis determination?

    PubMed

    Turner, Monte E; Ely, Daniel; Prokop, Jeremy; Milsted, Amy

    2011-09-01

    The Sry locus on the mammalian Y chromosome is the developmental switch responsible for testis determination. Inconsistent with this important function, the Sry locus is transcribed in adult males at times and in tissues not involved with testis determination. Sry is expressed in multiple tissues of the peripheral and central nervous system. Sry is derived from Sox3 and is similar to other SOXB family loci. The SOXB loci are responsible for nervous system development. Sry has been demonstrated to modulate the catecholamine pathway, so it should have functional consequences in the central and peripheral nervous system. The nervous system expression and potential function are consistent with Sry as a SOXB family member. In mammals, Sox3 is X-linked and undergoes dosage compensation in females. The expression of Sry in adult males allows for a type of sexual differentiation independent of circulating gonadal hormones. A quantitative difference in Sox3 plus Sry expression in males vs. females could drive changes in the transcriptome of these cells, differentiating male and female cells. Sry expression and its transcriptional effects should be considered when investigating sexual dimorphic phenotypes.

  16. The determinants of food choice.

    PubMed

    Leng, Gareth; Adan, Roger A H; Belot, Michele; Brunstrom, Jeffrey M; de Graaf, Kees; Dickson, Suzanne L; Hare, Todd; Maier, Silvia; Menzies, John; Preissl, Hubert; Reisch, Lucia A; Rogers, Peter J; Smeets, Paul A M

    2016-12-01

    Health nudge interventions to steer people into healthier lifestyles are increasingly applied by governments worldwide, and it is natural to look to such approaches to improve health by altering what people choose to eat. However, to produce policy recommendations that are likely to be effective, we need to be able to make valid predictions about the consequences of proposed interventions, and for this, we need a better understanding of the determinants of food choice. These determinants include dietary components (e.g. highly palatable foods and alcohol), but also diverse cultural and social pressures, cognitive-affective factors (perceived stress, health attitude, anxiety and depression), and familial, genetic and epigenetic influences on personality characteristics. In addition, our choices are influenced by an array of physiological mechanisms, including signals to the brain from the gastrointestinal tract and adipose tissue, which affect not only our hunger and satiety but also our motivation to eat particular nutrients, and the reward we experience from eating. Thus, to develop the evidence base necessary for effective policies, we need to build bridges across different levels of knowledge and understanding. This requires experimental models that can fill in the gaps in our understanding that are needed to inform policy, translational models that connect mechanistic understanding from laboratory studies to the real life human condition, and formal models that encapsulate scientific knowledge from diverse disciplines, and which embed understanding in a way that enables policy-relevant predictions to be made. Here we review recent developments in these areas.

  17. Secondary structure determines protein topology

    PubMed Central

    Fleming, Patrick J.; Gong, Haipeng; Rose, George D.

    2006-01-01

    Using a test set of 13 small, compact proteins, we demonstrate that a remarkably simple protocol can capture native topology from secondary structure information alone, in the absence of long-range interactions. It has been a long-standing open question whether such information is sufficient to determine a protein's fold. Indeed, even the far simpler problem of reconstructing the three-dimensional structure of a protein from its exact backbone torsion angles has remained a difficult challenge owing to the small, but cumulative, deviations from ideality in backbone planarity, which, if ignored, cause large errors in structure. As a familiar example, a small change in an elbow angle causes a large displacement at the end of your arm; the longer the arm, the larger the displacement. Here, correct secondary structure assignments (α-helix, β-strand, β-turn, polyproline II, coil) were used to constrain polypeptide backbone chains devoid of side chains, and the most stable folded conformations were determined, using Monte Carlo simulation. Just three terms were used to assess stability: molecular compaction, steric exclusion, and hydrogen bonding. For nine of the 13 proteins, this protocol restricts the main chain to a surprisingly small number of energetically favorable topologies, with the native one prominent among them. PMID:16823044

  18. [Determination of uranium in spinach].

    PubMed

    Kishi, Eri; Yutani, Aiko; Ozaki, Asako; Shinya, Masanao; Katahira, Kenshi; Ooshima, Tomoko; Shimizu, Mitsuru

    2013-01-01

    After the severe accident at the Fukushima-1 Nuclear Power Plant in March 2011, radioactive contamination of food has become a matter of serious concern in Japan. There is considerable information about radioactive iodine and cesium, but little is known about uranium contamination. We determined uranium content in spinach by the Japanese official method (Manual on Radiation Measurement of Food in Emergency Situations). In the preliminary study, we confirmed that the use of a microwave digestion system for preparing the test solution of spinach could shorten the testing time and give acceptable results. The manual recommends the use of two elements (Tl and Bi) as internal standards for measurement of uranium by ICP-MS. We found that Tl was more suitable than Bi to quantify trace amounts of uranium in spinach. However, it was necessary to determine Tl or Bi concentrations in the sample before analysis, since some samples of spinach contained significant amounts of these elements. The uranium contents of 9 spinach samples bought in April and May 2011 were less than 10 μg/kg, which are very low compared to the provisional regulatory limit in Japan.

  19. Determination of Silicon in Hydrazine

    NASA Technical Reports Server (NTRS)

    McClure, Mark B.; Mast, Dion; Greene, Ben; Maes, Miguel J.

    2006-01-01

    Inductively coupled plasma-mass spectrometry (ICP-MS) is a highly sensitive technique sometimes used for the trace determination of silicon at a mass-to-charge (m/z) ratio of 28, the most abundant natural isotope of silicon. Unfortunately, ICP-MS is unable to differentiate between other sources of m/z 28 and false positive results for silicon will result when other sources of m/z 28 are present. Nitrogen was a major source of m/z 28 and contributes to the m/z 28 signal when hydrazine sample or nitric acid preservative is introduced into the plasma. Accordingly, this work was performed to develop a sample preparation step coupled with an ICP-MS analysis that minimized non-silicon sources of m/z 28. In the preparatory step of this method, the hydrazine sample was first decomposed predominately to nitrogen gas and water with copper-catalyzed hydrogen peroxide. In the analysis step, ICP-MS was used without nitric acid preservative in samples or standards. Glass, a potential source of silicon contamination, was also avoided where possible. The method was sensitive, accurate, and reliable for the determination of silicon in monopropellant grade hydrazine (MPH) in AF-E-332 elastomer leaching tests. Results for silicon in MPH were comparable to those reported in the literature for other studies.

  20. Determination of a mutational spectrum

    DOEpatents

    Thilly, William G.; Keohavong, Phouthone

    1991-01-01

    A method of resolving (physically separating) mutant DNA from nonmutant DNA and a method of defining or establishing a mutational spectrum or profile of alterations present in nucleic acid sequences from a sample to be analyzed, such as a tissue or body fluid. The present method is based on the fact that it is possible, through the use of DGGE, to separate nucleic acid sequences which differ by only a single base change and on the ability to detect the separate mutant molecules. The present invention, in another aspect, relates to a method for determining a mutational spectrum in a DNA sequence of interest present in a population of cells. The method of the present invention is useful as a diagnostic or analytical tool in forensic science in assessing environmental and/or occupational exposures to potentially genetically toxic materials (also referred to as potential mutagens); in biotechnology, particularly in the study of the relationship between the amino acid sequence of enzymes and other biologically-active proteins or protein-containing substances and their respective functions; and in determining the effects of drugs, cosmetics and other chemicals for which toxicity data must be obtained.

  1. 78 FR 48703 - Proposed Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-09

    ... SECURITY Federal Emergency Management Agency Proposed Flood Hazard Determinations AGENCY: Federal Emergency... Register a proposed flood hazard determination notice that contained an erroneous table. This notice.... The table provided here represents the proposed flood hazard determinations and communities...

  2. Chandra Independently Determines Hubble Constant

    NASA Astrophysics Data System (ADS)

    2006-08-01

    A critically important number that specifies the expansion rate of the Universe, the so-called Hubble constant, has been independently determined using NASA's Chandra X-ray Observatory. This new value matches recent measurements using other methods and extends their validity to greater distances, thus allowing astronomers to probe earlier epochs in the evolution of the Universe. "The reason this result is so significant is that we need the Hubble constant to tell us the size of the Universe, its age, and how much matter it contains," said Max Bonamente from the University of Alabama in Huntsville and NASA's Marshall Space Flight Center (MSFC) in Huntsville, Ala., lead author on the paper describing the results. "Astronomers absolutely need to trust this number because we use it for countless calculations." Illustration of Sunyaev-Zeldovich Effect Illustration of Sunyaev-Zeldovich Effect The Hubble constant is calculated by measuring the speed at which objects are moving away from us and dividing by their distance. Most of the previous attempts to determine the Hubble constant have involved using a multi-step, or distance ladder, approach in which the distance to nearby galaxies is used as the basis for determining greater distances. The most common approach has been to use a well-studied type of pulsating star known as a Cepheid variable, in conjunction with more distant supernovae to trace distances across the Universe. Scientists using this method and observations from the Hubble Space Telescope were able to measure the Hubble constant to within 10%. However, only independent checks would give them the confidence they desired, considering that much of our understanding of the Universe hangs in the balance. Chandra X-ray Image of MACS J1149.5+223 Chandra X-ray Image of MACS J1149.5+223 By combining X-ray data from Chandra with radio observations of galaxy clusters, the team determined the distances to 38 galaxy clusters ranging from 1.4 billion to 9.3 billion

  3. 45 CFR 150.219 - Final determination.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ENFORCEMENT IN GROUP AND INDIVIDUAL INSURANCE MARKETS CMS Enforcement Processes for Determining Whether States... the State a written notice of its final determination. The notice includes the following:...

  4. Mars Science Laboratory Orbit Determination

    NASA Technical Reports Server (NTRS)

    Kruizinga, Gerhard; Gustafson, Eric; Jefferson, David; Martin-Mur, Tomas; Mottinger, Neil; Pelletier, Fred; Ryne, Mark; Thompson, Paul

    2012-01-01

    Mars Science Laboratory (MSL) Orbit Determination (OD) met all requirements with considerable margin, MSL OD team developed spin signature removal tool and successfully used the tool during cruise, A novel approach was used for the MSL solar radiation pressure model and resulted in a very accurate model during the approach phase, The change in velocity for Attitude Control System (ACS) turns was successfully calibrated and with appropriate scale factor resulted in improved change in velocity prediction for future turns, All Trajectory Correction Maneuvers were successfully reconstructed and execution errors were well below the assumed pre-fight execution errors, The official OD solutions were statistically consistent throughout cruise and for OD solutions with different arc lengths as well, Only EPU-1 was sent to MSL. All other Entry Parameter Updates were waived, EPU-1 solution was only 200 m separated from final trajectory reconstruction in the B-plane

  5. Attitude Determination Improvements for GOES

    NASA Technical Reports Server (NTRS)

    Crassidis, John L.; Markley, F. Landis; Kyle, Arthur M.; Kull, Kathie

    1996-01-01

    In this paper, a summary of the basic simulation parameters and results of a new study for the Geostationary Operational Environmental Satellite (GOES) is shown. The study for GOES involves the simulation of minor modifications to the current spacecraft, so that the relative performance of these modifications can be analyzed. The first modification studies requires the placement of a baseline inertial reference unit, such as the Dry Rotor Inertial Reference Unit or the Hemispherical Resonator Gyro onto the spacecraft. The imager/sounder assembly is currently used to obtain landmark and/or star observations in order to compensate for spacecraft motion and external disturbances through ground processing. The study uses the imager/sounder assembly as another attitude sensor for on-board attitude determination. Also the addition of star trackers is used to provide precise attitude knowledge.

  6. Social determinants and osteoarthritis outcomes

    PubMed Central

    Luong, My-Linh N; Cleveland, Rebecca J; Nyrop, Kirsten A; Callahan, Leigh F

    2012-01-01

    Osteoarthritis (OA) is one of the most frequently occurring musculoskeletal diseases, posing a significant public health problem due to its impact on pain and disability. Traditional risk factors fail to account for all of the risk observed for OA outcomes. In recent years, our view of disease causation has broadened to include health risks that are created by an individual’s socioeconomic circumstances. Early research into social determinants has focused on social position and explored factors related to the individual such as education, income and occupation. Results from these investigations suggest that low education attainment and nonprofessional occupation are associated with poorer arthritis outcomes. More recently, research has expanded to examine how one’s neighborhood socioeconomic environment may be relevant to OA outcomes. This narrative review proposes a framework to help guide our understanding of how social context may interact with pathophysiological processes and individual-level variables to influence health outcomes in those living with OA. PMID:23243459

  7. GRO attitude control and determination

    NASA Technical Reports Server (NTRS)

    Jerkovsky, W.; Keranen, L.; Koehler, F.; Tung, F.; Ward, B.

    1986-01-01

    Design features of the attitude control and determination (ACAD) system for the Gamma Ray Observatory (GRO) that will eventually be launched on the Shuttle are described. A tabulation of the ACAD system components is provided and the various standby and normal pointing operational modes of the system are summarized. The system software and sensors will maintain a quaternion model of the GRO attitude on the bases of kinematic equations and inertial data. The software is standardized and has previously been used on the Solar Maximum Mission and Landsat-D. Details of the processing components, redundant electronics for sensor processing, data handling and actuator control are outlined and illustrated with block diagrams. Tests applied to validate the ACAD design are outlined, as are ground support which will be implemented once the GRO is launched.

  8. Determination of Human Hemoglobin Derivatives.

    PubMed

    Attia, Atef M M; Ibrahim, Fatma A A; Abd El-Latif, Noha A; Aziz, Samir W; Abdelmottaleb Moussa, Sherif A; Elalfy, Mohsen S

    2015-01-01

    The levels of the inactive hemoglobin (Hb) pigments [such as methemoglobin (metHb), carboxyhemoglobin (HbCO) and sulfohemoglobin (SHb)] and the active Hb [in the oxyhemoglobin (oxyHb) form] as well as the blood Hb concentration in healthy non pregnant female volunteers were determined using a newly developed multi-component spectrophotometric method. The results of this method revealed values of SHb% in the range (0.0727-0.370%), metHb% (0.43-1.0%), HbCO% (0.4-1.52%) and oxyHb% (97.06-98.62%). Furthermore, the results of this method revealed values of blood Hb concentration in the range (12.608-15.777 g/dL). The method is highly sensitive, accurate and reproducible.

  9. Prospective errors determine motor learning

    PubMed Central

    Takiyama, Ken; Hirashima, Masaya; Nozaki, Daichi

    2015-01-01

    Diverse features of motor learning have been reported by numerous studies, but no single theoretical framework concurrently accounts for these features. Here, we propose a model for motor learning to explain these features in a unified way by extending a motor primitive framework. The model assumes that the recruitment pattern of motor primitives is determined by the predicted movement error of an upcoming movement (prospective error). To validate this idea, we perform a behavioural experiment to examine the model’s novel prediction: after experiencing an environment in which the movement error is more easily predictable, subsequent motor learning should become faster. The experimental results support our prediction, suggesting that the prospective error might be encoded in the motor primitives. Furthermore, we demonstrate that this model has a strong explanatory power to reproduce a wide variety of motor-learning-related phenomena that have been separately explained by different computational models. PMID:25635628

  10. Detecting determinism from point processes

    NASA Astrophysics Data System (ADS)

    Andrzejak, Ralph G.; Mormann, Florian; Kreuz, Thomas

    2014-12-01

    The detection of a nonrandom structure from experimental data can be crucial for the classification, understanding, and interpretation of the generating process. We here introduce a rank-based nonlinear predictability score to detect determinism from point process data. Thanks to its modular nature, this approach can be adapted to whatever signature in the data one considers indicative of deterministic structure. After validating our approach using point process signals from deterministic and stochastic model dynamics, we show an application to neuronal spike trains recorded in the brain of an epilepsy patient. While we illustrate our approach in the context of temporal point processes, it can be readily applied to spatial point processes as well.

  11. Determinants of Mammalian Nucleolar Architecture

    PubMed Central

    Farley, Katherine I.; Surovtseva, Yulia; Merkel, Janie; Baserga, Susan J.

    2015-01-01

    The nucleolus is responsible for the production of ribosomes, essential machines which synthesize all proteins needed by the cell. The structure of human nucleoli is highly dynamic and is directly related to its functions in ribosome biogenesis. Despite the importance of this organelle, the intricate relationship between nucleolar structure and function remains largely unexplored. How do cells control nucleolar formation and function? What are the minimal requirements for making a functional nucleolus? Here we review what is currently known regarding mammalian nucleolar formation at nucleolar organizer regions (NORs), which can be studied by observing the dissolution and reformation of the nucleolus during each cell division. Additionally, the nucleolus can be examined by analyzing how alterations in nucleolar function manifest in differences in nucleolar architecture. Furthermore, changes in nucleolar structure and function are correlated with cancer, highlighting the importance of studying the determinants of nucleolar formation. PMID:25670395

  12. Crystal structure determination of Efavirenz

    SciTech Connect

    Popeneciu, Horea Dumitru, Ristoiu; Tripon, Carmen Borodi, Gheorghe Pop, Mihaela Maria

    2015-12-23

    Needle-shaped single crystals of the title compound, C{sub 14}H{sub 9}ClF{sub 3}NO{sub 2}, were obtained from a co-crystallization experiment of Efavirenz with maleic acid in a (1:1) ratio, using methanol as solvent. Crystal structure determination at room temperature revealed a significant anisotropy of the lattice expansion compared to the previously reported low-temperature structure. In both low- and room temperature structures the cyclopropylethynyl fragment in one of the asymmetric unit molecules is disordered. While at low-temperature only one C atom exhibits positional disorder, at room temperature the disorder is present for two C atoms of the cyclopropane ring.

  13. Seasat. Volume 4: Attitude determination

    NASA Technical Reports Server (NTRS)

    Treder, A. J.

    1980-01-01

    The Seasat project was a feasibility demonstration of the use of orbital remote sensing for global ocean observation. The satellite was launched in June 1978 and was operated successfully until October 1978. A massive electrical failure occurred in the power system, terminating the mission prematurely. The actual implementation of the Seasat Attitude Determination system and the contents of the attitude data files generated by that system are documented. The deviations from plan caused by the anomalous Sun interference with horizon sensors, inflight calibration of Sun sensor head 2 alignment and horizon sensor biomass, estimation of yaw interpolation parameters, Sun and horizon sensor error sources, and yaw interpolation accuracy are included. Examples are given of flight attitude data from all modes of the Orbital Attitude Control System, of the ground processing effects on attitude data, and of cold cloud effects on pitch, and roll data.

  14. Crystal face temperature determination means

    DOEpatents

    Nason, Donald O.; Burger, Arnold

    1994-01-01

    An optically transparent furnace (10) having a detection apparatus (29) with a pedestal (12) enclosed in an evacuated ampule (16) for growing a crystal (14) thereon. Temperature differential is provided by a source heater (20), a base heater (24) and a cold finger (26) such that material migrates from a polycrystalline source material (18) to grow the crystal (14). A quartz halogen lamp (32) projects a collimated beam (30) onto the crystal (14) and a reflected beam (34) is analyzed by a double monochromator and photomultiplier detection spectrometer (40) and the detected peak position (48) in the reflected energy spectrum (44) of the reflected beam (34) is interpreted to determine surface temperature of the crystal (14).

  15. Gravity Probe B orbit determination

    NASA Astrophysics Data System (ADS)

    Shestople, P.; Ndili, A.; Hanuschak, G.; Parkinson, B. W.; Small, H.

    2015-11-01

    The Gravity Probe B (GP-B) satellite was equipped with a pair of redundant Global Positioning System (GPS) receivers used to provide navigation solutions for real-time and post-processed orbit determination (OD), as well as to establish the relation between vehicle time and coordinated universal time. The receivers performed better than the real-time position requirement of 100 m rms per axis. Post-processed solutions indicated an rms position error of 2.5 m and an rms velocity error of 2.2 mm s-1. Satellite laser ranging measurements provided independent verification of the GPS-derived GP-B orbit. We discuss the modifications and performance of the Trimble Advance Navigation System Vector III GPS receivers. We describe the GP-B precision orbit and detail the OD methodology, including ephemeris errors and the laser ranging measurements.

  16. Experimental Determination of Ramsey Numbers

    NASA Astrophysics Data System (ADS)

    Bian, Zhengbing; Chudak, Fabian; Macready, William G.; Clark, Lane; Gaitan, Frank

    2013-09-01

    Ramsey theory is a highly active research area in mathematics that studies the emergence of order in large disordered structures. Ramsey numbers mark the threshold at which order first appears and are extremely difficult to calculate due to their explosive rate of growth. Recently, an algorithm that can be implemented using adiabatic quantum evolution has been proposed that calculates the two-color Ramsey numbers R(m,n). Here we present results of an experimental implementation of this algorithm and show that it correctly determines the Ramsey numbers R(3,3) and R(m,2) for 4≤m≤8. The R(8,2) computation used 84 qubits of which 28 were computational qubits. This computation is the largest experimental implementation of a scientifically meaningful adiabatic evolution algorithm that has been done to date.

  17. Experimental determination of Ramsey numbers.

    PubMed

    Bian, Zhengbing; Chudak, Fabian; Macready, William G; Clark, Lane; Gaitan, Frank

    2013-09-27

    Ramsey theory is a highly active research area in mathematics that studies the emergence of order in large disordered structures. Ramsey numbers mark the threshold at which order first appears and are extremely difficult to calculate due to their explosive rate of growth. Recently, an algorithm that can be implemented using adiabatic quantum evolution has been proposed that calculates the two-color Ramsey numbers R(m,n). Here we present results of an experimental implementation of this algorithm and show that it correctly determines the Ramsey numbers R(3,3) and R(m,2) for 4≤m≤8. The R(8,2) computation used 84 qubits of which 28 were computational qubits. This computation is the largest experimental implementation of a scientifically meaningful adiabatic evolution algorithm that has been done to date.

  18. Novel gene complex structure determination

    SciTech Connect

    Gatewood, J.M.

    1997-08-01

    This is the final report of a one-year, Laboratory-Directed Research and Development (LORD) project at the Los Alamos National Laboratory. `Operative` chromatin containing exclusively the minor hasten variants was successfully isolated. Linker hasten H1 is quantitatively missing from operative chromatin. One of the aims of this proposal was to determine the proteins responsible for stabilizing operative chromatin. This chromatin is stabilized by microtubule proteins tar and tubulin. Another goal of this project was the structural characterization of operate chromatin nucleosomes. Using solution scattering, nucleosomes containing the minor variants were shown to be structurally distinct from major variant containing nucleosomes. The unusual structure and stabilization of operative chromatin by microtubule proteins provides a possible mechanism for direct interaction of transcription machinery with specific chromatin domains.

  19. Structural determinants of glomerular permeability.

    PubMed

    Deen, W M; Lazzara, M J; Myers, B D

    2001-10-01

    Recent progress in relating the functional properties of the glomerular capillary wall to its unique structure is reviewed. The fenestrated endothelium, glomerular basement membrane (GBM), and epithelial filtration slits form a series arrangement in which the flow diverges as it enters the GBM from the fenestrae and converges again at the filtration slits. A hydrodynamic model that combines morphometric findings with water flow data in isolated GBM has predicted overall hydraulic permeabilities that are consistent with measurements in vivo. The resistance of the GBM to water flow, which accounts for roughly half that of the capillary wall, is strongly dependent on the extent to which the GBM surfaces are blocked by cells. The spatial frequency of filtration slits is predicted to be a very important determinant of the overall hydraulic permeability, in keeping with observations in several glomerular diseases in humans. Whereas the hydraulic resistances of the cell layers and GBM are additive, the overall sieving coefficient for a macromolecule (its concentration in Bowman's space divided by that in plasma) is the product of the sieving coefficients for the individual layers. Models for macromolecule filtration reveal that the individual sieving coefficients are influenced by one another and by the filtrate velocity, requiring great care in extrapolating in vitro observations to the living animal. The size selectivity of the glomerular capillary has been shown to be determined largely by the cellular layers, rather than the GBM. Controversial findings concerning glomerular charge selectivity are reviewed, and it is concluded that there is good evidence for a role of charge in restricting the transmural movement of albumin. Also discussed is an effect of albumin that has received little attention, namely, its tendency to increase the sieving coefficients of test macromolecules via steric interactions. Among the unresolved issues are the specific contributions of the

  20. Predictors of a health-promoting life-style among well adult clients in a nursing practice.

    PubMed

    Frauman, A C; Nettles-Carlson, B

    1991-01-01

    The self-reported health-promoting life-style (HPL) of 130 well adults in a primary care clinical population was examined in relation to the cognitive/perceptual and sociodemographic factors hypothesized in Pender's Health Promotion Model (1987) to predict this behavior. Subjects were randomly drawn from the clients of a group nurse practitioner practice emphasizing health maintenance. Data were collected by mailed survey (response rate, 59%) with one telephone prompt. The mean age of the subjects was 39.7 years; 72.3% were female; 51.2% were married; 47.7% had college degrees; and 67.4% were white. Blacks were underrepresented in the sample compared to the practice population (chi = 7.56, p = .006). Using multiple regression, the definition of health, importance of health, health locus of control, age, gender, marital status, race, education, income, and rural/urban residence were studied to determine their effects on health-promoting behavior. Results generally supported the Pender Model. Defining health eudiamonistically, that is, as exuberant well-being (rather than adaptive, functional, or absence of disease), predicted HPL. Ranking health above other values such as achievement and harmony had no effect; chance health locus of control had a negative relationship. In the final regression model, predictors of HPL were eudiamonistic conception of health and college education (p = .0001, R2 = 17). Based on this data, considerations of a clients' health conception when framing health-promotion messages is warranted in this population.

  1. Determinants of female sexual orgasms

    PubMed Central

    Kontula, Osmo; Miettinen, Anneli

    2016-01-01

    Background The pursuit of sexual pleasure is a key motivating factor in sexual activity. Many things can stand in the way of sexual orgasms and enjoyment, particularly among women. These are essential issues of sexual well-being and gender equality. Objective This study presents long-term trends and determinants of female orgasms in Finland. The aim is to analyze the roles of factors such as the personal importance of orgasms, sexual desire, masturbation, clitoral and vaginal stimulation, sexual self-esteem, communication with partner, and partner’s sexual techniques. Design In Finland, five national sex surveys that are based on random samples from the central population register have been conducted. They are representative of the total population within the age range of 18–54 years in 1971 (N=2,152), 18–74 years in 1992 (N=2,250), 18–81 years in 1999 (N=1,496), 18–74 years in 2007 (N=2,590), and 18–79 years in 2015 (N=2,150). Another dataset of 2,049 women in the age group of 18–70 years was collected in 2015 via a national Internet panel. Results Contrary to expectations, women did not have orgasms that are more frequent by increasing their experience and practice of masturbation, or by experimenting with different partners in their lifetime. The keys to their more frequent orgasms lay in mental and relationship factors. These factors and capacities included orgasm importance, sexual desire, sexual self-esteem, and openness of sexual communication with partners. Women valued their partner’s orgasm more than their own. In addition, positive determinants were the ability to concentrate, mutual sexual initiations, and partner’s good sexual techniques. A relationship that felt good and worked well emotionally, and where sex was approached openly and appreciatively, promoted orgasms. Conclusion The findings indicate that women differ greatly from one another in terms of their tendency and capacity to experience orgasms. The improvements in gender

  2. Nondestructive Determination of Bond Strength

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Although many nondestructive techniques have been applied to detect disbonds in adhesive joints, no absolutely reliable nondestructive method has been developed to detect poor adhesion and evaluate the strength of bonded joints prior to the present work which used nonlinear ultrasonic methods to investigate adhesive bond cure conditions. Previously, a variety of linear and nonlinear ultrasonic methods with water coupling had been used to study aluminum-adhesive-aluminum laminates, prepared under different adhesive curing conditions, for possible bond strength determination. Therefore, in the course of this research effort, a variety of finite-amplitude experimental methods which could possibly differentiate various cure conditions were investigated, including normal and oblique incidence approaches based on nonlinear harmonic generation as well as several non-collinear two-wave interaction approaches. Test samples were mechanically scanned in various ways with respect to the focus of a transmitting transducer operated at several variable excitation frequencies and excitation levels. Even when powerful sample-related resonances were exploited by means of a frequency scanning approach, it was very difficult to isolate the nonlinear characteristics of adhesive bonds. However, a multi-frequency multi-power approach was quite successful and reliable. Ultrasonic tone burst signals at increasing power levels, over a wide frequency range, were transmitted through each bond specimen to determine its excitation dependent nonlinear harmonic resonance behavior. Relative amplitude changes were observed particularly in the higher harmonic spectral data and analyzed using a local displacement and strain analysis in the linear approximation. Two analysis approaches of the excitation-dependent data at specific resonances were found to be quite promising. One of these approaches may represent a very robust algorithm for classifying an adhesive bond as being properly cured or not

  3. 20 CFR 405.101 - Disability determinations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Disability determinations. 405.101 Section... ADJUDICATING INITIAL DISABILITY CLAIMS Initial Determinations § 405.101 Disability determinations. The State... this chapter or both. The disability examiner will make a determination based on all of the...

  4. 40 CFR 230.11 - Factual determinations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the potential short-term or long-term effects of a proposed discharge of dredged or fill material on... determination. The determinations of effects of each proposed discharge shall include the following: (a) Physical substrate determinations. Determine the nature and degree of effect that the proposed...

  5. 20 CFR 416.1207 - Resources determinations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Resources determinations. 416.1207 Section..., BLIND, AND DISABLED Resources and Exclusions § 416.1207 Resources determinations. (a) General. Resources determinations are made as of the first moment of the month. A resource determination is based on what assets...

  6. 20 CFR 416.1207 - Resources determinations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Resources determinations. 416.1207 Section..., BLIND, AND DISABLED Resources and Exclusions § 416.1207 Resources determinations. (a) General. Resources determinations are made as of the first moment of the month. A resource determination is based on what assets...

  7. 20 CFR 416.1207 - Resources determinations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Resources determinations. 416.1207 Section..., BLIND, AND DISABLED Resources and Exclusions § 416.1207 Resources determinations. (a) General. Resources determinations are made as of the first moment of the month. A resource determination is based on what assets...

  8. 20 CFR 416.1207 - Resources determinations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Resources determinations. 416.1207 Section..., BLIND, AND DISABLED Resources and Exclusions § 416.1207 Resources determinations. (a) General. Resources determinations are made as of the first moment of the month. A resource determination is based on what assets...

  9. 20 CFR 416.1207 - Resources determinations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Resources determinations. 416.1207 Section..., BLIND, AND DISABLED Resources and Exclusions § 416.1207 Resources determinations. (a) General. Resources determinations are made as of the first moment of the month. A resource determination is based on what assets...

  10. 20 CFR 405.101 - Disability determinations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Disability determinations. 405.101 Section... ADJUDICATING INITIAL DISABILITY CLAIMS Initial Determinations § 405.101 Disability determinations. The State... this chapter or both. The disability examiner will make a determination based on all of the...

  11. Closed and open conformations of the lid domain induce different patterns of human pancreatic lipase antigenicity and immunogenicity.

    PubMed

    Halimi, Hubert; De Caro, Josiane; Carrière, Frédéric; De Caro, Alain

    2005-12-01

    Epitope mapping was performed on human pancreatic lipase (HPL) using the SPOTscan method. A set of 146 short (12 amino acid residues) synthetic overlapping peptides covering the entire amino acid sequence of HPL were used to systematically assess the immunoreactivity of antisera raised in rabbits against native HPL, HPL without a lid (HPL(-lid)) and HPL covalently inhibited by diethyl p-nitrophenyl phosphate (DP-HPL). In the latter form of HPL, the lid domain controlling the access to the active site was assumed to exist in the open conformation. All the anti-lipase sera were tested in a direct ELISA, anti-HPL serum showing the greatest antibody titer. Although from the structural point of view, the differences between the various forms of HPL were restricted to the lid domain, differences in the antigenic properties of HPL were observed with the SPOTscan method, and the anti-DP-HPL antibodies showed the strongest reactivity. Most of the peptide stretches recognized included amino acid residues which are accessible at the surface of the lipase, except for those located near the active site. Two small peptides (T173-P180, V199-A207) were identified in the vicinity of the active site, their antipeptide antibodies were produced and their reactivity towards the various forms of HPL was tested in a double sandwich ELISA. No reactivity was observed under these conditions. Two antipeptide antibodies directed against two other selected peptides, P208-V221 (belonging to the beta9 loop) and I245-F258 (belonging to the lid domain) were prepared and found to react much more strongly with DP-HPL than with HPL or HPL(-lid) in a double sandwich ELISA. These antibodies should provide useful tools for monitoring the conformational changes taking place during the opening of the HPL lid domain.

  12. Ballistic projectile trajectory determining system

    DOEpatents

    Karr, T.J.

    1997-05-20

    A computer controlled system determines the three-dimensional trajectory of a ballistic projectile. To initialize the system, predictions of state parameters for a ballistic projectile are received at an estimator. The estimator uses the predictions of the state parameters to estimate first trajectory characteristics of the ballistic projectile. A single stationary monocular sensor then observes the actual first trajectory characteristics of the ballistic projectile. A comparator generates an error value related to the predicted state parameters by comparing the estimated first trajectory characteristics of the ballistic projectile with the observed first trajectory characteristics of the ballistic projectile. If the error value is equal to or greater than a selected limit, the predictions of the state parameters are adjusted. New estimates for the trajectory characteristics of the ballistic projectile are made and are then compared with actual observed trajectory characteristics. This process is repeated until the error value is less than the selected limit. Once the error value is less than the selected limit, a calculator calculates trajectory characteristics such a the origin and destination of the ballistic projectile. 8 figs.

  13. Ballistic projectile trajectory determining system

    DOEpatents

    Karr, Thomas J.

    1997-01-01

    A computer controlled system determines the three-dimensional trajectory of a ballistic projectile. To initialize the system, predictions of state parameters for a ballistic projectile are received at an estimator. The estimator uses the predictions of the state parameters to estimate first trajectory characteristics of the ballistic projectile. A single stationary monocular sensor then observes the actual first trajectory characteristics of the ballistic projectile. A comparator generates an error value related to the predicted state parameters by comparing the estimated first trajectory characteristics of the ballistic projectile with the observed first trajectory characteristics of the ballistic projectile. If the error value is equal to or greater than a selected limit, the predictions of the state parameters are adjusted. New estimates for the trajectory characteristics of the ballistic projectile are made and are then compared with actual observed trajectory characteristics. This process is repeated until the error value is less than the selected limit. Once the error value is less than the selected limit, a calculator calculates trajectory characteristics such a the origin and destination of the ballistic projectile.

  14. Determinants of fatigue and stress

    PubMed Central

    2011-01-01

    Background Fatigue can be triggered by previous perceived stress which may lead to impairment of performance and function. The purpose of the study was to investigate the relationship between fatigue and perceived stress. Method Health determinants including sociodemographic factors for associations between fatigue and perceived stress in the general population (N = 2,483) are outlined. Fatigue and stress were assessed with the Chalder Fatigue Scale (CFS) and the Perceived Stress Questionnaire (PSQ). Results Within the general population, 25.9% of male and 34.5% of female respondents reported moderate fatigue during the last six months; 9.7% of subjects reported substantial fatigue lasting six months or longer. An adjusted regression analysis (R2corr = .28, p < .001) showed that fatigue is highest associated with perceived stress and self-perceived health status. The following factors were correlated with increased rates of fatigue and perceived stress: female gender, divorce/separation, low social class and poor health status. Conclusion We conclude that the two conditions overlap most in terms of socio-economic status and self-perceived health status. PMID:21774803

  15. Neuronal factors determining high intelligence.

    PubMed

    Dicke, Ursula; Roth, Gerhard

    2016-01-05

    Many attempts have been made to correlate degrees of both animal and human intelligence with brain properties. With respect to mammals, a much-discussed trait concerns absolute and relative brain size, either uncorrected or corrected for body size. However, the correlation of both with degrees of intelligence yields large inconsistencies, because although they are regarded as the most intelligent mammals, monkeys and apes, including humans, have neither the absolutely nor the relatively largest brains. The best fit between brain traits and degrees of intelligence among mammals is reached by a combination of the number of cortical neurons, neuron packing density, interneuronal distance and axonal conduction velocity--factors that determine general information processing capacity (IPC), as reflected by general intelligence. The highest IPC is found in humans, followed by the great apes, Old World and New World monkeys. The IPC of cetaceans and elephants is much lower because of a thin cortex, low neuron packing density and low axonal conduction velocity. By contrast, corvid and psittacid birds have very small and densely packed pallial neurons and relatively many neurons, which, despite very small brain volumes, might explain their high intelligence. The evolution of a syntactical and grammatical language in humans most probably has served as an additional intelligence amplifier, which may have happened in songbirds and psittacids in a convergent manner.

  16. Social network determinants of depression

    PubMed Central

    Rosenquist, JN; Fowler, JH; Christakis, NA

    2013-01-01

    The etiology of depression has long been thought to include social environmental factors. To quantitatively explore the novel possibility of person-to-person spread and network-level determination of depressive symptoms, analyses were performed on a densely interconnected social network of 12 067 people assessed repeatedly over 32 years as part of the Framingham Heart Study. Longitudinal statistical models were used to examine whether depressive symptoms in one person were associated with similar scores in friends, co-workers, siblings, spouses and neighbors. Depressive symptoms were assessed using CES-D scores that were available for subjects in three waves measured between 1983 and 2001. Results showed both low and high CES-D scores (and classification as being depressed) in a given period were strongly correlated with such scores in one's friends and neighbors. This association extended up to three degrees of separation (to one's friends’ friends’ friends). Female friends appear to be especially influential in the spread of depression from one person to another. The results are robust to multiple network simulation and estimation methods, suggesting that network phenomena appear relevant to the epidemiology of depression and would benefit from further study. PMID:20231839

  17. Spectrophotometric determination of protein concentration.

    PubMed

    Simonian, Michael H

    2004-09-01

    This unit describes spectrophotometric and colorimetric methods for measuring the concentration of a sample protein in solution. Absorbance measured at 280 nm (A(280)) is used to calculate protein concentration by comparison with a standard curve or published absorptivity values for that protein (a(280)). Alternatively, absorbance measured at 205 nm (A(205)) is used to calculate the protein concentration. The A(280) and A(205) methods can be used to quantify total protein in crude lysates and purified or partially purified protein. A spectrofluorometer or a filter fluorometer can be used to measure the intrinsic fluorescence emission of a sample solution; this value is compared with the emissions from standard solutions to determine the sample concentration. The fluorescence emission method is used to quantify purified protein. This simple method is useful for dilute protein samples and can be completed in a short amount of time. There are two colorimetric methods: the Bradford colorimetric method, based upon binding of the dye Coomassie brilliant blue to the protein of interest, and the Lowry method, which measures colorimetric reaction of tyrosyl residues in the protein sample.

  18. Lunge performance and its determinants.

    PubMed

    Cronin, John; McNair, Peter J; Marshall, Robert N

    2003-01-01

    For activities such as squash, badminton and fencing, the ability to quickly complete a lunge and return to the start or move off in another direction is critical for success. Determining which strength qualities are important predictors of lunge performance was the focus of this study. Thirty-one male athletes performed: (1) a unilateral maximal squat (one-repetition maximum, 1-RM) and unilateral jump squat (50% 1-RM) on an instrumented supine squat machine, and (2) a forward lunge while attached to a linear transducer. We performed stepwise multiple regression analysis with lunge performance as the dependent variable and various strength, flexibility and anthropometric measures as the independent variables. From the many strength and power measures calculated, time to peak force was the best single predictor of lunge performance, which accounted for 55% of the explained variance. The best three-variable model for predicting lunge performance accounted for 76-85% of the explained variance. The models differed, however, according to whether lunge performance was expressed relative to body mass (time to peak force, mean power and relative strength = 76%) or taken as an absolute value (time to peak force, leg length and flexibility = 85%). We conclude that one to two trials were reliable for strength diagnosis and that one strength measure cannot accurately explain functional performance because other factors, such as body mass, flexibility and leg length, have diverse effects on the statistical models.

  19. Determinants of pulmonary blood volume

    PubMed Central

    Lewis, Milena L.; Gnoj, Julian; Fisher, Vincent J.; Christianson, Lynn C.

    1970-01-01

    Pulmonary blood volume was determined by the radiocardiographic technique in 49 patients coming to cardiac catheterization. Since this method has not been directly compared with the more commonly used double injection of dye. 25 comparisons were carried out in 13 patients of the series. Agreement was good over a range of 4.5-21.1 heart cycles since there was no statistically significant difference between transit time values measured by the two methods. The relation of pulmonary blood volume to other hemodynamic factors in these 49 patients, with and without cardiac or pulmonary disease, was evaluated by means of multiple regression analysis. The analysis carried out for mean transit time indicates that this parameter varies predominately with flow. Pulmonary blood volume, in this series of resting recumbent individuals, varies to a significant degree only with total blood volume and with pulmonary venous pressure. No parameters of vascular distensibility, such as pulmonary vascular resistance, were found to affect the volume of blood in the lungs. The fact that variations in pulmonary blood volume among the subjects could be described by a multiple regression equation linear with respect to total blood volume and pulmonary venous pressure indicates that these variations are the result of passive distention of components of the vascular bed. PMID:4902826

  20. Neuronal factors determining high intelligence

    PubMed Central

    Dicke, Ursula; Roth, Gerhard

    2016-01-01

    Many attempts have been made to correlate degrees of both animal and human intelligence with brain properties. With respect to mammals, a much-discussed trait concerns absolute and relative brain size, either uncorrected or corrected for body size. However, the correlation of both with degrees of intelligence yields large inconsistencies, because although they are regarded as the most intelligent mammals, monkeys and apes, including humans, have neither the absolutely nor the relatively largest brains. The best fit between brain traits and degrees of intelligence among mammals is reached by a combination of the number of cortical neurons, neuron packing density, interneuronal distance and axonal conduction velocity—factors that determine general information processing capacity (IPC), as reflected by general intelligence. The highest IPC is found in humans, followed by the great apes, Old World and New World monkeys. The IPC of cetaceans and elephants is much lower because of a thin cortex, low neuron packing density and low axonal conduction velocity. By contrast, corvid and psittacid birds have very small and densely packed pallial neurons and relatively many neurons, which, despite very small brain volumes, might explain their high intelligence. The evolution of a syntactical and grammatical language in humans most probably has served as an additional intelligence amplifier, which may have happened in songbirds and psittacids in a convergent manner. PMID:26598734

  1. Computational advances in nanostructure determination

    NASA Astrophysics Data System (ADS)

    Farrow, Christopher Lyn

    The atomic pair distribution function (PDF) and extended x-ray absorption fine structure (EXAFS) techniques fill a hole in conventional crystallographic analysis, which resolves the average long-range structure of a material but inadequately determines deviations from the average. These techniques provide structural information on the sub-nanometer scale and are helping characterize modern materials. Despite their successes, PDF and EXAFS often fall short of adequately describing complex nanostructured materials. Parallel PDF and EXAFS refinement, or corefinement, is one attempt at extending the applicability of these techniques. Corefinement combines the best parts of PDF and EXAFS, the chemical-specific and short-range detail of EXAFS and the short and intermediate-range information from the PDF. New ab initio methods are also being employed to find structures from the PDF. These techniques use the bond length information encoded in the PDF to assemble structures without a model. On another front, new software has been developed to introduce the PDF method to a larger community. Broad awareness of the PDF technique will help drive its future development.

  2. Determining GPS average performance metrics

    NASA Technical Reports Server (NTRS)

    Moore, G. V.

    1995-01-01

    Analytic and semi-analytic methods are used to show that users of the GPS constellation can expect performance variations based on their location. Specifically, performance is shown to be a function of both altitude and latitude. These results stem from the fact that the GPS constellation is itself non-uniform. For example, GPS satellites are over four times as likely to be directly over Tierra del Fuego than over Hawaii or Singapore. Inevitable performance variations due to user location occur for ground, sea, air and space GPS users. These performance variations can be studied in an average relative sense. A semi-analytic tool which symmetrically allocates GPS satellite latitude belt dwell times among longitude points is used to compute average performance metrics. These metrics include average number of GPS vehicles visible, relative average accuracies in the radial, intrack and crosstrack (or radial, north/south, east/west) directions, and relative average PDOP or GDOP. The tool can be quickly changed to incorporate various user antenna obscuration models and various GPS constellation designs. Among other applications, tool results can be used in studies to: predict locations and geometries of best/worst case performance, design GPS constellations, determine optimal user antenna location and understand performance trends among various users.

  3. Human platelet lysate is an alternative to fetal bovine serum for large-scale expansion of bone marrow-derived mesenchymal stromal cells.

    PubMed

    Gottipamula, Sanjay; Sharma, Archana; Krishnamurthy, Sagar; Majumdar, Anish Sen; Seetharam, Raviraja N

    2012-07-01

    Human platelet lysate (HPL) was evaluated as an alternative to fetal bovine serum (FBS) in large-scale culturing of bone marrow-derived mesenchymal stromal cells (BM-MSCs) for therapeutic applications. Dulbecco's modified Eagle medium (DMEM)of low glucose (LG) and Knock Out (KO) were used with human platelet lysate (HPL) as LG-HPL and KO-HPL, and with FBS as LG-FBS and KO-FBS to culture the BM-MSCs. HPL at 10 % (v/v) supported BM-MSCs growth and subsequent isolation efficiency generated >90 × 10(6) MSCs in LG-HPL. Population doublings (PDs) and population doubling times of LG-HPL and KO-HPL (PDT) were not significantly different but LG-HPL showed a significant clonogenic potential and HPL cultures had an average PDT of 36.5 ± 6.5 h and an average PDs of 5 ± 0.7/passage. BM-MSCs cultured with LG-HPL had significantly higher immunosuppression compared to LG-FBS, but KO-HPL and KO-FBS-grown cultures were not significantly different. HPL is therefore alternative to FBS for large-scale production of BM-MSCs for therapeutic applications.

  4. Tackling the diversity of sex determination.

    PubMed

    Wedekind, Claus; Stelkens, Rike B

    2010-02-23

    A workshop on 'The evolution of sex determination systems' was held at a remote place in the Swiss Alps from 17 to 20 June 2009. It brought together theoreticians and empiricists, the latter ranging from molecular geneticists to evolutionary ecologists, all trying to understand key aspects of sex determination. The topics discussed included the evolutionary origins of sex determination, the diversity of sex determination mechanisms in different taxa, and the transition from genotypic to environmental sex determination and vice versa.

  5. Determinants of first practice location

    PubMed Central

    Raghavan, Malathi; Fleisher, William; Downs, Allan; Martin, Bruce; Sandham, J. Dean

    2012-01-01

    Abstract Objective To help understand physician movement out of Manitoba by determining the factors that influence Manitoba medical graduates’ choices about practice locations. Design Cross-sectional, within-stage, mixed-model survey. Setting Manitoba. Participants All University of Manitoba medical graduates from classes 1998 to 2009 for whom we had valid contact information (N = 912 of 943 graduates) were invited in August 2009 to participate in a survey. Main outcome measures Demographic information; ratings, on a 5-point scale, of the importance when choosing first practice locations of 12 practice characteristics, 3 recruitment strategies, and 4 location characteristics listed in the survey; free-text narratives on unlisted factors; and estimates of likely practice location upon completion of training for recent graduates still in residency training. Results Completed surveys were received from 331 (35.1%) graduates of the surveyed classes, 162 (53.3%) of whom chose Manitoba for their first practice location. Multiple regression analyses indicated that graduates choosing Manitoba for their first practice location were significantly more likely to have done their residency training in Manitoba (P < .05), whether or not they gave a high rating to the importance of being near family and friends. Also, graduates choosing Manitoba were significantly more likely to be recent graduates (P = .007) and less likely to be members of a visible minority (P = .018). These associations were robust even when analyses were restricted to responses from practitioners without cause to estimate practice locations. Early self-selection of graduates during entry into specific residency programs, results of the residency match process, and “putting down roots” during residency years were 3 important interrelated themes identified through qualitative analyses. Conclusion Residency education in Manitoba is the overwhelming factor influencing graduates’ choice of Manitoba as

  6. [Virulence determinant of Chromobacterium violaceum].

    PubMed

    Miki, Tsuyoshi

    2014-01-01

    Chromobacterium violaceum is a Gram-negative bacterium that infects humans and animals with fatal sepsis. The infection with C. violaceum is rare in case of those who are healthy, but once established, C. violaceum causes sever disease accompanied by abscess formation in the lungs, liver and spleen. Furthermore, C. violaceum is resistant to a broad range of antibiotics, which in some cases renders the antimicrobial therapy for this infection difficult. Thus, the infection with C. violaceum displays high mortality rates unless initial proper antimicrobial therapy. In contrast, the infection mechanism had completely remained unknown. To this end, we have tried to identify virulence factors-associated with C. violaceum infection. Two distinct type III secretion systems (TTSSs) were thought to be one of the most important virulence factors, which are encoded by Chromobacterium pathogenicity island 1/1a and 2 (Cpi-1/-1a and -2) respectively. Our results have shown that Cpi-1/-1a-encoded TTSS, but not Cpi-2, is indispensable for the virulence in a mouse infection model. C. violaceum caused fulminant hepatitis in a Cpi-1/-1a-encoded TTSS-dependent manner. We next have identified 16 novel effectors secreted from Cpi-1/-1a-encoded TTS machinery. From these effectors, we found that CopE (Chromobacterium outer protein E) has similarities to a guanine nucleotide exchange factor (GEF) for Rho GTPases. CopE acts as GEF for Rac1 and Cdc42, leading to induction of actin cytoskeletal rearrangement. Interestingly, C. violaceum invades cultured human epithelial cells in a CopE-dependent manner. Finally, an inactivation of CopE by disruption of copE gene or amino acid point mutation leading to loss of GEF activity attenuates significantly the mouse virulence of C. violaceum. These results suggest that Cpi-1/-1a-encoded TTSS is a major virulence determinant for C. violaceum infection, and that CopE contributes to the virulence in part of this pathogen.

  7. Plant traits determine forest flammability

    NASA Astrophysics Data System (ADS)

    Zylstra, Philip; Bradstock, Ross

    2016-04-01

    Carbon and nutrient cycles in forest ecosystems are influenced by their inherent flammability - a property determined by the traits of the component plant species that form the fuel and influence the micro climate of a fire. In the absence of a model capable of explaining the complexity of such a system however, flammability is frequently represented by simple metrics such as surface fuel load. The implications of modelling fire - flammability feedbacks using surface fuel load were examined and compared to a biophysical, mechanistic model (Forest Flammability Model) that incorporates the influence of structural plant traits (e.g. crown shape and spacing) and leaf traits (e.g. thickness, dimensions and moisture). Fuels burn with values of combustibility modelled from leaf traits, transferring convective heat along vectors defined by flame angle and with plume temperatures that decrease with distance from the flame. Flames are re-calculated in one-second time-steps, with new leaves within the plant, neighbouring plants or higher strata ignited when the modelled time to ignition is reached, and other leaves extinguishing when their modelled flame duration is exceeded. The relative influence of surface fuels, vegetation structure and plant leaf traits were examined by comparing flame heights modelled using three treatments that successively added these components within the FFM. Validation was performed across a diverse range of eucalypt forests burnt under widely varying conditions during a forest fire in the Brindabella Ranges west of Canberra (ACT) in 2003. Flame heights ranged from 10 cm to more than 20 m, with an average of 4 m. When modelled from surface fuels alone, flame heights were on average 1.5m smaller than observed values, and were predicted within the error range 28% of the time. The addition of plant structure produced predicted flame heights that were on average 1.5m larger than observed, but were correct 53% of the time. The over-prediction in this

  8. 77 FR 18842 - Proposed Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-28

    ... SECURITY Federal Emergency Management Agency Proposed Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: Comments are requested on proposed flood hazard determinations, which may include additions or modifications of any Base Flood Elevation (BFE), base flood...

  9. 78 FR 5824 - Proposed Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-28

    ... SECURITY Federal Emergency Management Agency Proposed Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: Comments are requested on proposed flood hazard determinations, which may include additions or modifications of any Base Flood Elevation (BFE), base flood...

  10. 77 FR 18846 - Proposed Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-28

    ... SECURITY Federal Emergency Management Agency Proposed Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: Comments are requested on proposed flood hazard determinations, which may include additions or modifications of any Base Flood Elevation (BFE), base flood...

  11. 78 FR 5821 - Final Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-28

    ... SECURITY Federal Emergency Management Agency Final Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Final Notice. SUMMARY: Flood hazard determinations, which may include additions or modifications of Base Flood Elevations (BFEs), base flood depths, Special Flood Hazard...

  12. 78 FR 21143 - Final Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-09

    ... SECURITY Federal Emergency Management Agency Final Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Final notice. SUMMARY: Flood hazard determinations, which may include additions or modifications of Base Flood Elevations (BFEs), base flood depths, Special Flood Hazard...

  13. 78 FR 21143 - Proposed Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-09

    ... SECURITY Federal Emergency Management Agency Proposed Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: Comments are requested on proposed flood hazard determinations, which may include additions or modifications of any Base Flood Elevation (BFE), base flood...

  14. 77 FR 18839 - Proposed Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-28

    ... SECURITY Federal Emergency Management Agency Proposed Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: Comments are requested on proposed flood hazard determinations, which may include additions or modifications of any Base Flood Elevation (BFE), base flood...

  15. 78 FR 52953 - Final Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-27

    ... SECURITY Federal Emergency Management Agency Final Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Final Notice. SUMMARY: Flood hazard determinations, which may include additions or modifications of Base Flood Elevations (BFEs), base flood depths, Special Flood Hazard...

  16. 77 FR 18844 - Proposed Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-28

    ... SECURITY Federal Emergency Management Agency Proposed Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: Comments are requested on proposed flood hazard determinations, which may include additions or modifications of any Base Flood Elevation (BFE), base flood...

  17. 78 FR 48701 - Proposed Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-09

    ... SECURITY Federal Emergency Management Agency Proposed Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: Comments are requested on proposed flood hazard determinations, which may include additions or modifications of any Base Flood Elevation (BFE), base flood...

  18. 77 FR 18835 - Proposed Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-28

    ... SECURITY Federal Emergency Management Agency Proposed Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: Comments are requested on proposed flood hazard determinations, which may include additions or modifications of any Base Flood Elevation (BFE), base flood...

  19. 78 FR 52954 - Final Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-27

    ... SECURITY Federal Emergency Management Agency Final Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Final notice. SUMMARY: Flood hazard determinations, which may include additions or modifications of Base Flood Elevations (BFEs), base flood depths, Special Flood Hazard...

  20. 78 FR 5820 - Final Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-28

    ... SECURITY Federal Emergency Management Agency Final Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Final Notice. SUMMARY: Flood hazard determinations, which may include additions or modifications of Base Flood Elevations (BFEs), base flood depths, Special Flood Hazard...

  1. 78 FR 5822 - Proposed Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-28

    ... SECURITY Federal Emergency Management Agency Proposed Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: Comments are requested on proposed flood hazard determinations, which may include additions or modifications of any Base Flood Elevation (BFE), base flood...

  2. 77 FR 74859 - Proposed Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-18

    ... SECURITY Federal Emergency Management Agency Proposed Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: Comments are requested on proposed flood hazard determinations, which may include additions or modifications of any Base Flood Elevation (BFE), base flood...

  3. 78 FR 5826 - Proposed Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-28

    ... SECURITY Federal Emergency Management Agency Proposed Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: Comments are requested on proposed flood hazard determinations, which may include additions or modifications of any Base Flood Elevation (BFE), base flood...

  4. 78 FR 49277 - Proposed Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-13

    ... SECURITY Federal Emergency Management Agency Proposed Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: Comments are requested on proposed flood hazard determinations, which may include additions or modifications of any Base Flood Elevation (BFE), base flood...

  5. 78 FR 49278 - Proposed Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-13

    ... SECURITY Federal Emergency Management Agency Proposed Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: Comments are requested on proposed flood hazard determinations, which may include additions or modifications of any Base Flood Elevation (BFE), base flood...

  6. 77 FR 18841 - Proposed Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-28

    ... SECURITY Federal Emergency Management Agency Proposed Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: Comments are requested on proposed flood hazard determinations, which may include additions or modifications of any Base Flood Elevation (BFE), base flood...

  7. 7 CFR 51.1416 - Optional determinations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... classification content for the lot. (d) Kernel moisture content. The sample of pecans for determination of kernel moisture content shall be shelled immediately before analysis and all shells, center wall and other non... used for moisture content determination....

  8. 40 CFR 230.11 - Factual determinations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... circulation, fluctuation, and salinity determinations. Determine the nature and degree of effect that the..., salinity, clarity, color, odor, taste, dissolved gas levels, temperature, nutrients, and eutrophication... effects on the current patterns, water circulation, normal water fluctuation and salinity shall...

  9. 40 CFR 230.11 - Factual determinations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... circulation, fluctuation, and salinity determinations. Determine the nature and degree of effect that the..., salinity, clarity, color, odor, taste, dissolved gas levels, temperature, nutrients, and eutrophication... effects on the current patterns, water circulation, normal water fluctuation and salinity shall...

  10. 40 CFR 230.11 - Factual determinations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... circulation, fluctuation, and salinity determinations. Determine the nature and degree of effect that the..., salinity, clarity, color, odor, taste, dissolved gas levels, temperature, nutrients, and eutrophication... effects on the current patterns, water circulation, normal water fluctuation and salinity shall...

  11. 40 CFR 230.11 - Factual determinations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... circulation, fluctuation, and salinity determinations. Determine the nature and degree of effect that the..., salinity, clarity, color, odor, taste, dissolved gas levels, temperature, nutrients, and eutrophication... effects on the current patterns, water circulation, normal water fluctuation and salinity shall...

  12. 10 CFR 963.11 - Suitability determination.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... DEPARTMENT OF ENERGY YUCCA MOUNTAIN SITE SUITABILITY GUIDELINES Site Suitability Determination, Methods, and Criteria § 963.11 Suitability determination. DOE will evaluate whether the Yucca Mountain site is suitable... determinations described in §§ 963.12 and 963.15. If DOE's evaluation of the Yucca Mountain site for the...

  13. 10 CFR 963.11 - Suitability determination.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... DEPARTMENT OF ENERGY YUCCA MOUNTAIN SITE SUITABILITY GUIDELINES Site Suitability Determination, Methods, and Criteria § 963.11 Suitability determination. DOE will evaluate whether the Yucca Mountain site is suitable... determinations described in §§ 963.12 and 963.15. If DOE's evaluation of the Yucca Mountain site for the...

  14. 10 CFR 963.11 - Suitability determination.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... DEPARTMENT OF ENERGY YUCCA MOUNTAIN SITE SUITABILITY GUIDELINES Site Suitability Determination, Methods, and Criteria § 963.11 Suitability determination. DOE will evaluate whether the Yucca Mountain site is suitable... determinations described in §§ 963.12 and 963.15. If DOE's evaluation of the Yucca Mountain site for the...

  15. 10 CFR 963.11 - Suitability determination.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... DEPARTMENT OF ENERGY YUCCA MOUNTAIN SITE SUITABILITY GUIDELINES Site Suitability Determination, Methods, and Criteria § 963.11 Suitability determination. DOE will evaluate whether the Yucca Mountain site is suitable... determinations described in §§ 963.12 and 963.15. If DOE's evaluation of the Yucca Mountain site for the...

  16. 10 CFR 963.11 - Suitability determination.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... DEPARTMENT OF ENERGY YUCCA MOUNTAIN SITE SUITABILITY GUIDELINES Site Suitability Determination, Methods, and Criteria § 963.11 Suitability determination. DOE will evaluate whether the Yucca Mountain site is suitable... determinations described in §§ 963.12 and 963.15. If DOE's evaluation of the Yucca Mountain site for the...

  17. Determining Salary Equity: Policies, Procedures, and Problems

    ERIC Educational Resources Information Center

    Braskamp, Larry A.; And Others

    1978-01-01

    A three-phase salary review process conducted at one university is used to illustrate issues involved in determining salary equity. It describes salary policies, determining possible discrimination due to minority group status and determining salary adjustments of individual faculty in the minority group being discriminated against. (Author/LBH)

  18. 24 CFR 954.302 - Income determinations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Income determinations. 954.302... DEVELOPMENT INDIAN HOME PROGRAM Eligible Activities and Affordability § 954.302 Income determinations. Whenever a grantee makes a determination under this part based on family income or adjusted family...

  19. 24 CFR 954.302 - Income determinations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Income determinations. 954.302... DEVELOPMENT INDIAN HOME PROGRAM Eligible Activities and Affordability § 954.302 Income determinations. Whenever a grantee makes a determination under this part based on family income or adjusted family...

  20. Simple colorimetric method determines uranium in tissue

    NASA Technical Reports Server (NTRS)

    Doran, D.; Frigerio, N. A.

    1967-01-01

    Simple colorimetric micromethod determines concentrations of uranium in tissue. The method involves dry ashing organic extraction, and colorimetric determination of uranyl ferrocyanide. This uranium determination technique could be used in agricultural research, tracer studies, testing of food products, or medical research.

  1. 7 CFR 1955.63 - Suitability determination.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) PROGRAM REGULATIONS (CONTINUED) PROPERTY MANAGEMENT Management of Property § 1955.63 Suitability determination. As soon as real property is acquired, a determination must be made as to whether or not the property can be used for program purposes. The suitability determination will be recorded in the...

  2. 7 CFR 1955.63 - Suitability determination.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) PROGRAM REGULATIONS (CONTINUED) PROPERTY MANAGEMENT Management of Property § 1955.63 Suitability determination. As soon as real property is acquired, a determination must be made as to whether or not the property can be used for program purposes. The suitability determination will be recorded in the...

  3. 7 CFR 1955.63 - Suitability determination.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) PROGRAM REGULATIONS (CONTINUED) PROPERTY MANAGEMENT Management of Property § 1955.63 Suitability determination. As soon as real property is acquired, a determination must be made as to whether or not the property can be used for program purposes. The suitability determination will be recorded in the...

  4. 78 FR 52956 - Proposed Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-27

    ... SECURITY Federal Emergency Management Agency Proposed Flood Hazard Determinations AGENCY: Federal Emergency... Register (78 FR 36220-36222) a proposed flood hazard determination notice that contained an erroneous table... FR 36220. The table provided here represents the proposed flood hazard determinations and...

  5. 20 CFR 404.920 - Reconsidered determination.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Reconsidered determination. 404.920 Section 404.920 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Determinations, Administrative Review Process, and Reopening of Determinations...

  6. 42 CFR 422.566 - Organization determinations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 3 2011-10-01 2011-10-01 false Organization determinations. 422.566 Section 422... (CONTINUED) MEDICARE PROGRAM MEDICARE ADVANTAGE PROGRAM Grievances, Organization Determinations and Appeals § 422.566 Organization determinations. (a) Responsibilities of the MA organization. Each MA...

  7. 42 CFR 422.566 - Organization determinations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 3 2014-10-01 2014-10-01 false Organization determinations. 422.566 Section 422... (CONTINUED) MEDICARE PROGRAM (CONTINUED) MEDICARE ADVANTAGE PROGRAM Grievances, Organization Determinations and Appeals § 422.566 Organization determinations. (a) Responsibilities of the MA organization....

  8. 42 CFR 422.566 - Organization determinations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 3 2012-10-01 2012-10-01 false Organization determinations. 422.566 Section 422... (CONTINUED) MEDICARE PROGRAM (CONTINUED) MEDICARE ADVANTAGE PROGRAM Grievances, Organization Determinations and Appeals § 422.566 Organization determinations. (a) Responsibilities of the MA organization....

  9. 42 CFR 422.566 - Organization determinations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Organization determinations. 422.566 Section 422... (CONTINUED) MEDICARE PROGRAM MEDICARE ADVANTAGE PROGRAM Grievances, Organization Determinations and Appeals § 422.566 Organization determinations. (a) Responsibilities of the MA organization. Each MA...

  10. 42 CFR 422.566 - Organization determinations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 3 2013-10-01 2013-10-01 false Organization determinations. 422.566 Section 422... (CONTINUED) MEDICARE PROGRAM (CONTINUED) MEDICARE ADVANTAGE PROGRAM Grievances, Organization Determinations and Appeals § 422.566 Organization determinations. (a) Responsibilities of the MA organization....

  11. 42 CFR 423.641 - Contract determinations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 3 2012-10-01 2012-10-01 false Contract determinations. 423.641 Section 423.641... (CONTINUED) MEDICARE PROGRAM (CONTINUED) VOLUNTARY MEDICARE PRESCRIPTION DRUG BENEFIT Medicare Contract Determinations and Appeals § 423.641 Contract determinations. This subpart establishes the procedures...

  12. 42 CFR 423.641 - Contract determinations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Contract determinations. 423.641 Section 423.641... (CONTINUED) MEDICARE PROGRAM VOLUNTARY MEDICARE PRESCRIPTION DRUG BENEFIT Medicare Contract Determinations and Appeals § 423.641 Contract determinations. This subpart establishes the procedures for...

  13. 42 CFR 422.641 - Contract determinations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 3 2012-10-01 2012-10-01 false Contract determinations. 422.641 Section 422.641... (CONTINUED) MEDICARE PROGRAM (CONTINUED) MEDICARE ADVANTAGE PROGRAM Medicare Contract Determinations and Appeals § 422.641 Contract determinations. This subpart establishes the procedures for making...

  14. 42 CFR 422.641 - Contract determinations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Contract determinations. 422.641 Section 422.641... (CONTINUED) MEDICARE PROGRAM MEDICARE ADVANTAGE PROGRAM Medicare Contract Determinations and Appeals § 422.641 Contract determinations. This subpart establishes the procedures for making and reviewing...

  15. 7 CFR 51.1416 - Optional determinations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... (INSPECTION, CERTIFICATION, AND STANDARDS) United States Standards for Grades of Pecans in the Shell 1... or as a separate determination. Samples of pecans for these determinations shall be taken at random... least 500 grams of in-shell pecans shall be used for determination of edible kernel content. After...

  16. 7 CFR 51.1416 - Optional determinations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... STANDARDS) United States Standards for Grades of Pecans in the Shell 1 Optional Determinations § 51.1416... determination. Samples of pecans for these determinations shall be taken at random from a composite sample drawn throughout the lot. (a) Edible kernel content. A minimum sample of at least 500 grams of in-shell...

  17. 7 CFR 51.1416 - Optional determinations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... STANDARDS) United States Standards for Grades of Pecans in the Shell 1 Optional Determinations § 51.1416... determination. Samples of pecans for these determinations shall be taken at random from a composite sample drawn throughout the lot. (a) Edible kernel content. A minimum sample of at least 500 grams of in-shell...

  18. 33 CFR 136.309 - Advertisement determinations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Advertisement determinations. 136... PROCEDURES; DESIGNATION OF SOURCE; AND ADVERTISEMENT Designation of Source and Advertisement § 136.309 Advertisement determinations. (a) The Director, NPFC, determines for each incident the type, geographic...

  19. 38 CFR 36.4707 - Determination fees.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) LOAN GUARANTY Sale of Loans, Guarantee of Payment, and Flood Insurance § 36.4707 Determination fees. (a... a reasonable fee for determining whether the building or mobile home securing the loan is located or... building or mobile home securing the loan is located; or (ii) By determination of the Director of FEMA,...

  20. 14 CFR 415.7 - Payload determination.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Payload determination. 415.7 Section 415.7 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING LAUNCH LICENSE General § 415.7 Payload determination. A payload determination...

  1. 14 CFR 415.7 - Payload determination.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Payload determination. 415.7 Section 415.7 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING LAUNCH LICENSE General § 415.7 Payload determination. A payload determination...

  2. 14 CFR 415.7 - Payload determination.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Payload determination. 415.7 Section 415.7 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING LAUNCH LICENSE General § 415.7 Payload determination. A payload determination...

  3. 14 CFR 415.7 - Payload determination.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Payload determination. 415.7 Section 415.7 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING LAUNCH LICENSE General § 415.7 Payload determination. A payload determination...

  4. 14 CFR 415.7 - Payload determination.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Payload determination. 415.7 Section 415.7 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING LAUNCH LICENSE General § 415.7 Payload determination. A payload determination...

  5. 18 CFR 158.6 - Determination.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Determination. 158.6 Section 158.6 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT....6 Determination. If no formal hearing is had the matter in issue will be determined by...

  6. 18 CFR 41.6 - Determination.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Determination. 41.6 Section 41.6 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF....6 Determination. If no formal hearing is had the matter in issue will be determined by...

  7. 18 CFR 41.6 - Determination.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Determination. 41.6 Section 41.6 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF....6 Determination. If no formal hearing is had the matter in issue will be determined by...

  8. 18 CFR 158.6 - Determination.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Determination. 158.6 Section 158.6 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT....6 Determination. If no formal hearing is had the matter in issue will be determined by...

  9. 24 CFR 2004.25 - Final determination.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... IN RESPONSE TO SUBPOENAS OR DEMANDS OF COURTS OR OTHER AUTHORITIES Requests for Testimony and Production of Documents § 2004.25 Final determination. The Counsel makes the final determination on demands... determination, the reasons for the grant or denial of the demand or request, and any conditions that the...

  10. Tackling the diversity of sex determination

    PubMed Central

    Wedekind, Claus; Stelkens, Rike B.

    2010-01-01

    A workshop on ‘The evolution of sex determination systems’ was held at a remote place in the Swiss Alps from 17 to 20 June 2009. It brought together theoreticians and empiricists, the latter ranging from molecular geneticists to evolutionary ecologists, all trying to understand key aspects of sex determination. The topics discussed included the evolutionary origins of sex determination, the diversity of sex determination mechanisms in different taxa, and the transition from genotypic to environmental sex determination and vice versa. PMID:19692397

  11. Human platelet lysate gel provides a novel three dimensional-matrix for enhanced culture expansion of mesenchymal stromal cells.

    PubMed

    Walenda, Gudrun; Hemeda, Hatim; Schneider, Rebekka K; Merkel, Rudolf; Hoffmann, Bernd; Wagner, Wolfgang

    2012-12-01

    Cell culture in regenerative medicine needs to facilitate efficient expansion according to good manufacturing practice requirements. Human platelet lysate (HPL) can be used as a substitute for fetal calf serum without the risk of xenogeneic immune reactions or transmission of bovine pathogens. Heparin needs to be added as anticoagulant before addition of HPL to culture medium; otherwise, HPL-medium forms a gel within 1 h. Here, we demonstrated that such HPL-gels provide a suitable 3D-matrix for cell culture that-apart from heparin-consists of the same components as the over-layered culture medium. Mesenchymal stromal cells (MSCs) grew in several layers at the interface between HPL-gel and HPL-medium without contact with any artificial biomaterials. Notably, proliferation of MSCs was much higher on HPL-gel compared with tissue culture plastic. Further, the frequency of initial fibroblastoid colony forming units (CFU-f) increased on HPL-gel. The viscous consistency of HPL-gel enabled passaging with a convenient harvesting and reseeding procedure by pipetting cells together with their HPL-matrix-this method does not require washing steps and can easily be automated. The immunophenotype and in vitro differentiation potential toward adipogenic, osteogenic, and chondrogenic lineage were not affected by culture-isolation on HPL-gel. Taken together, HPL-gel has many advantages over conventional plastic surfaces: it facilitates enhanced CFU-f outgrowth, increased proliferation rates, higher cell densities, and nonenzymatic passaging procedures for culture expansion of MSCs.

  12. Sex determination in forensic odontology: A review

    PubMed Central

    Ramakrishnan, K.; Sharma, Subramanya; Sreeja, C.; Pratima, D. Bhavani; Aesha, I.; Vijayabanu, B.

    2015-01-01

    Forensic odontology is the application of dental principles to legal issues. Sex determination is a subdivision of forensic odontology and it is very important especially when information relating to the deceased is unavailable. Sex determination becomes the first priority in the process of identification of a person by a forensic investigator in the case of mishaps, chemical and nuclear bomb explosions, natural disasters crime investigations, and ethnic studies. This article reviews upon the various methods used in sex determination. PMID:26538886

  13. Determinants of Long Bone Structural Properties

    NASA Technical Reports Server (NTRS)

    Cleek, T. M.; Katz, B.; Whalen, R. T.; Wade, Charles E. (Technical Monitor)

    1994-01-01

    The objective of our research is to determine whether a non-invasive determination of long bone cross-sectional areal properties using only the mineral component of bone accurately predicts the true structural properties. In this study section properties of a whole long bone were compared using two methods: (1) special analysis of bone densitometry data, and (2) experimental determination of flexural rigidities from bone surface strain measurements during controlled loading.

  14. Sex determination in forensic odontology: A review.

    PubMed

    Ramakrishnan, K; Sharma, Subramanya; Sreeja, C; Pratima, D Bhavani; Aesha, I; Vijayabanu, B

    2015-08-01

    Forensic odontology is the application of dental principles to legal issues. Sex determination is a subdivision of forensic odontology and it is very important especially when information relating to the deceased is unavailable. Sex determination becomes the first priority in the process of identification of a person by a forensic investigator in the case of mishaps, chemical and nuclear bomb explosions, natural disasters crime investigations, and ethnic studies. This article reviews upon the various methods used in sex determination.

  15. Methods for threshold determination in multiplexed assays

    DOEpatents

    Tammero, Lance F. Bentley; Dzenitis, John M; Hindson, Benjamin J

    2014-06-24

    Methods for determination of threshold values of signatures comprised in an assay are described. Each signature enables detection of a target. The methods determine a probability density function of negative samples and a corresponding false positive rate curve. A false positive criterion is established and a threshold for that signature is determined as a point at which the false positive rate curve intersects the false positive criterion. A method for quantitative analysis and interpretation of assay results together with a method for determination of a desired limit of detection of a signature in an assay are also described.

  16. Determination of Blastoderm Cells in Drosophila melanogaster

    PubMed Central

    Chan, L.-N.; Gehring, W.

    1971-01-01

    A method for culturing blastoderm cells of Drosophila in vivo has been developed that allows these cells to differentiate into larval or adult structures. By intermixture of genetically marked cells from bisected and whole embryos, it was shown that blastoderm cells are restricted in their potential for forming adult epidermal structures. Cells isolated from anterior-half embryos are determined for forming head and thoracic structures, whereas cells from posterior-half embryos are determined for forming thoracic and abdominal structures. The specificity of determination and the localization of determinative factors is discussed. Images PMID:5002429

  17. Selectivity of catalytic methods of determination.

    PubMed

    Otto, M; Mueller, H; Werner, G

    1978-03-01

    By means of catalytic analytical methods, extremely low levels can be determined at low cost and with a high sensitivity that is equal to that of physical methods of trace analysis. The selectivity of the catalytic determinations, is, however, usually rather lower than that of other methods of trace analysis. The selectivity can sometimes be improved by modification of the indicator reaction through variation of the reagents and their concentrations, or by use of masking reagents or activators, or by combination with a separation method. Modification of the indicator reaction can be exemplified by the selective determination of osmium and ruthenium by their catalysis of the nitrate oxidation of 1-naphthylamine. By variation of the nitrate concentration and the use of 1,10-phenanthroline and 8-hydroxyquinoline as complexing agents it is possible to determine these two elements simultaneously. An especially significant increase in the selectivity is made possible by use of a preliminary separation step. If the ion to be determined is separated by solvent extraction and then catalytically determined directly in the extract, a very specific determination is possible; this technique has been called "extractive catalytic determination". This method has been used for determination of molybdenum (0.5 ng/ml) in sea-water, iron (5 ng/ml) in heavy metal salts, and copper (3 ng/ml) in the presence of numerous elements.

  18. Uncertainty of in-flight thrust determination

    NASA Technical Reports Server (NTRS)

    Abernethy, Robert B.; Adams, Gary R.; Steurer, John W.; Ascough, John C.; Baer-Riedhart, Jennifer L.; Balkcom, George H.; Biesiadny, Thomas

    1986-01-01

    Methods for estimating the measurement error or uncertainty of in-flight thrust determination in aircraft employing conventional turbofan/turbojet engines are reviewed. While the term 'in-flight thrust determination' is used synonymously with 'in-flight thrust measurement', in-flight thrust is not directly measured but is determined or calculated using mathematical modeling relationships between in-flight thrust and various direct measurements of physical quantities. The in-flight thrust determination process incorporates both ground testing and flight testing. The present text is divided into the following categories: measurement uncertainty methodoogy and in-flight thrust measurent processes.

  19. 7 CFR 947.113 - Area determinations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE IRISH POTATOES GROWN IN MODOC AND... Definitions § 947.113 Area determinations. Immediate production area, and immediate shipping...

  20. 7 CFR 947.113 - Area determinations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE IRISH POTATOES GROWN IN MODOC AND... Definitions § 947.113 Area determinations. Immediate production area, and immediate shipping...

  1. 48 CFR 846.471 - Determination authority.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Determination authority. 846.471 Section 846.471 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS CONTRACT MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance 846.471 Determination authority....

  2. Information Measures for Statistical Orbit Determination

    ERIC Educational Resources Information Center

    Mashiku, Alinda K.

    2013-01-01

    The current Situational Space Awareness (SSA) is faced with a huge task of tracking the increasing number of space objects. The tracking of space objects requires frequent and accurate monitoring for orbit maintenance and collision avoidance using methods for statistical orbit determination. Statistical orbit determination enables us to obtain…

  3. 37 CFR 501.7 - Agency determination.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... UNIFORM PATENT POLICY FOR RIGHTS IN INVENTIONS MADE BY GOVERNMENT EMPLOYEES § 501.7 Agency determination... agency determines, pursuant to paragraph (a)(2) or (a)(4) of § 501.6, that title to an invention will be... to § 501.6(a)(2) where the Government's insufficient interest in the invention is evidenced by...

  4. 37 CFR 501.7 - Agency determination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... UNIFORM PATENT POLICY FOR RIGHTS IN INVENTIONS MADE BY GOVERNMENT EMPLOYEES § 501.7 Agency determination... agency determines, pursuant to paragraph (a)(2) or (a)(4) of § 501.6, that title to an invention will be... to § 501.6(a)(2) where the Government's insufficient interest in the invention is evidenced by...

  5. Using Mobile Learning: Determinates Impacting Behavioral Intention

    ERIC Educational Resources Information Center

    Lowenthal, Jeffrey N.

    2010-01-01

    This study examined the factors or determinates that impact the behavioral intention of students to use mobile learning (m-learning) technology. These determinates include performance expectancy, effort expectancy, and self-management of learning, all mediated by age, gender, or both. Regression coefficients showed strong and significant…

  6. 14 CFR 77.31 - Determinations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false Determinations. 77.31 Section 77.31 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRSPACE SAFE, EFFICIENT USE, AND PRESERVATION OF THE NAVIGABLE AIRSPACE Aeronautical Studies and Determinations §...

  7. 14 CFR 77.31 - Determinations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Determinations. 77.31 Section 77.31 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRSPACE SAFE, EFFICIENT USE, AND PRESERVATION OF THE NAVIGABLE AIRSPACE Aeronautical Studies and Determinations §...

  8. 14 CFR 77.31 - Determinations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Determinations. 77.31 Section 77.31 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRSPACE SAFE, EFFICIENT USE, AND PRESERVATION OF THE NAVIGABLE AIRSPACE Aeronautical Studies and Determinations §...

  9. 29 CFR 500.145 - Registration determinations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Registration determinations. 500.145 Section 500.145 Labor... SEASONAL AGRICULTURAL WORKER PROTECTION Enforcement § 500.145 Registration determinations. Section 500.51... revoke, a Certificate of Registration (including a Farm Labor Contractor Employee Certificate...

  10. 29 CFR 500.145 - Registration determinations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 3 2014-07-01 2014-07-01 false Registration determinations. 500.145 Section 500.145 Labor... SEASONAL AGRICULTURAL WORKER PROTECTION Enforcement § 500.145 Registration determinations. Section 500.51... revoke, a Certificate of Registration (including a Farm Labor Contractor Employee Certificate...

  11. 29 CFR 500.145 - Registration determinations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 3 2012-07-01 2012-07-01 false Registration determinations. 500.145 Section 500.145 Labor... SEASONAL AGRICULTURAL WORKER PROTECTION Enforcement § 500.145 Registration determinations. Section 500.51... revoke, a Certificate of Registration (including a Farm Labor Contractor Employee Certificate...

  12. 29 CFR 500.145 - Registration determinations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 3 2013-07-01 2013-07-01 false Registration determinations. 500.145 Section 500.145 Labor... SEASONAL AGRICULTURAL WORKER PROTECTION Enforcement § 500.145 Registration determinations. Section 500.51... revoke, a Certificate of Registration (including a Farm Labor Contractor Employee Certificate...

  13. 29 CFR 500.145 - Registration determinations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Registration determinations. 500.145 Section 500.145 Labor... SEASONAL AGRICULTURAL WORKER PROTECTION Enforcement § 500.145 Registration determinations. Section 500.51... revoke, a Certificate of Registration (including a Farm Labor Contractor Employee Certificate...

  14. 12 CFR 1102.5 - Subcommittee determination.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 9 2012-01-01 2012-01-01 false Subcommittee determination. 1102.5 Section 1102.5 Banks and Banking FEDERAL FINANCIAL INSTITUTIONS EXAMINATION COUNCIL APPRAISER REGULATION Temporary Waiver Requests § 1102.5 Subcommittee determination. Within 45 calendar days of the date of...

  15. 24 CFR 92.203 - Income determinations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Income determinations. 92.203... Development HOME INVESTMENT PARTNERSHIPS PROGRAM Program Requirements § 92.203 Income determinations. (a) The HOME program has income targeting requirements for the HOME program and for HOME projects....

  16. 24 CFR 92.203 - Income determinations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Income determinations. 92.203... Development HOME INVESTMENT PARTNERSHIPS PROGRAM Program Requirements § 92.203 Income determinations. (a) The HOME program has income targeting requirements for the HOME program and for HOME projects....

  17. 78 FR 14576 - Final Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-06

    ... SECURITY Federal Emergency Management Agency Final Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Final Notice. SUMMARY: Flood hazard determinations, which may include... management measures that a community is required either to adopt or to show evidence of having in effect...

  18. 76 FR 46715 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-03

    ... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY... proposed determinations of Base (1% annual-chance) Flood Elevations (BFEs) and modified BFEs for communities participating in the National Flood Insurance Program (NFIP), in accordance with section 110...

  19. 77 FR 22551 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-16

    ... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY...) publishes proposed determinations of Base (1% annual-chance) Flood Elevations (BFEs) and modified BFEs for communities participating in the National Flood Insurance Program (NFIP), in accordance with section 110...

  20. 76 FR 13572 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-14

    ... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY... Emergency Management Agency (FEMA) publishes proposed determinations of Base (1% annual-chance) Flood Elevations (BFEs) and modified BFEs for communities participating in the National Flood Insurance...

  1. 77 FR 46994 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-07

    ... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY...) publishes proposed determinations of Base (1% annual-chance) Flood Elevations (BFEs) and modified BFEs for communities participating in the National Flood Insurance Program (NFIP), in accordance with section 110...

  2. 77 FR 76998 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-31

    ... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY... (FEMA) publishes proposed determinations of Base (1% annual-chance) Flood Elevations (BFEs) and modified BFEs for communities participating in the National Flood Insurance Program (NFIP), in accordance...

  3. 77 FR 67324 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-09

    ... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY... (FEMA) publishes proposed determinations of Base (1% annual-chance) Flood Elevations (BFEs) and modified BFEs for communities participating in the National Flood Insurance Program (NFIP), in accordance...

  4. 77 FR 74142 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-13

    ... Docket No. FEMA-B-1100 and FEMA-B-1222] Proposed Flood Elevation Determinations AGENCY: Federal Emergency... Management Agency (FEMA) publishes proposed determinations of Base (1% annual-chance) Flood Elevations (BFEs) and modified BFEs for communities participating in the National Flood Insurance Program (NFIP),...

  5. 77 FR 70454 - Proposed Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-26

    ... SECURITY Federal Emergency Management Agency Proposed Flood Hazard Determinations AGENCY: Federal Emergency... Register a ] proposed flood hazard determination notice at FR 77 44651 that contained a table which included a Web page address through which the Preliminary Flood Insurance Rate Map (FIRM), and...

  6. 77 FR 67325 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-09

    ... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY...) publishes proposed determinations of Base (1% annual-chance) Flood Elevations (BFEs) and modified BFEs for communities participating in the National Flood Insurance Program (NFIP), in accordance with section 110...

  7. 77 FR 29678 - Proposed Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-18

    ... FEMA-2012-0003: Internal Agency Docket No. FEMA-B-1251] Proposed Flood Hazard Determinations AGENCY... flood hazard determinations, which may include additions or modifications of any Base Flood Elevation (BFE), base flood depth, Special Flood Hazard Area (SFHA) boundary or zone designation, or...

  8. 36 CFR 297.5 - Determination.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 297.5 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE WILD AND SCENIC RIVERS Water Resources Projects § 297.5 Determination. (a) The Secretary of Agriculture will consent to... determined that: (1) The water resources project will not have a direct and adverse effect on the values...

  9. 40 CFR 231.5 - Recommended determination.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Recommended determination. 231.5 Section 231.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c) PROCEDURES § 231.5 Recommended determination. (a) The Regional Administrator or his...

  10. 49 CFR 107.221 - Determination.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... material transportation law or the regulations issued thereunder and does not unreasonably burden commerce... unreasonably burdens commerce, the Chief Counsel considers: (1) The extent to which increased costs and... Register, at which time the determination becomes a final agency action. (e) A determination under...

  11. Determinants of Success during Triathalon Competition.

    ERIC Educational Resources Information Center

    Dengel, Donald R.; And Others

    1989-01-01

    Eleven male triathletes were studied to determine the relationships between selected metabolic measurements and triathalon performance. Oxygen uptake, pulmonary ventilation, and heart rate were measured during freestyle swimming, cycling, and treadmill running. Economy of effort was an important determinant of performance. (JD)

  12. 75 FR 39277 - Sorbitol From France; Determination

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-08

    ... From the Federal Register Online via the Government Publishing Office INTERNATIONAL TRADE COMMISSION Sorbitol From France; Determination On the basis of the record \\1\\ developed in the subject five-year review, the United States International Trade Commission (Commission) determines, pursuant to section 751(c) of the Tariff Act of 1930 (19...

  13. Wage Determination and Discrimination among Older Workers.

    ERIC Educational Resources Information Center

    Quinn, Joseph F.

    1979-01-01

    Analyzed determinants of wage rates of older workers and the large discrepancies existing between wage earned by Whites, non-Whites, men, and women. Human capital and geographic variables were important wage determinants. Differences in variables cannot completely explain the wage differentials of race and sex. (Author)

  14. Ultrasonic modulus determination in composite media

    NASA Technical Reports Server (NTRS)

    Kline, R. A.; Sahay, S. K.; Madaras, E. I.

    1991-01-01

    A nondestructive test procedure for determining the elastic properties of anisotropic media is presented. The technique is based on transit time measurements for multiple angles of incidence and a numerical solution of the resulting coupled nonlinear equations for modulus determination. Methods for compensating for energy flux deviation from the wave normal and the resulting differences group and phase velocity are devised.

  15. 36 CFR 908.33 - Final determination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... final determination on the claim within 45 days of receipt of the file from the Director of Real Estate... sent to the aggrieved person and to the Director of Real Estate. (b) If the applicant is determined to have been aggrieved, the Director of Real Estate shall promptly take appropriate action in...

  16. 78 FR 43905 - Final Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-22

    ... SECURITY Federal Emergency Management Agency Final Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Final Notice. SUMMARY: Flood hazard determinations, which may include... management measures that a community is required either to adopt or to show evidence of having in effect...

  17. 78 FR 43904 - Final Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-22

    ... SECURITY Federal Emergency Management Agency Final Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Final notice. SUMMARY: Flood hazard determinations, which may include... management measures ] that a community is required either to adopt or to show evidence of having in effect...

  18. 78 FR 43904 - Final Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-22

    ... SECURITY Federal Emergency Management Agency Final Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Final Notice. SUMMARY: Flood hazard determinations, which may include... management measures that a community is required either to adopt or to show evidence of having in effect...

  19. 78 FR 29763 - Final Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-21

    ... SECURITY Federal Emergency Management Agency Final Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Final Notice. SUMMARY: Flood hazard determinations, which may include... management measures that a community is required either to adopt or to show evidence of having in effect...

  20. 78 FR 45938 - Final Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-30

    ... SECURITY Federal Emergency Management Agency Final Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Final notice. SUMMARY: Flood hazard determinations, which may include... management measures that a community is required either to adopt or to show evidence of having in effect...

  1. 42 CFR 417.838 - Organization determinations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 3 2012-10-01 2012-10-01 false Organization determinations. 417.838 Section 417... (CONTINUED) MEDICARE PROGRAM (CONTINUED) HEALTH MAINTENANCE ORGANIZATIONS, COMPETITIVE MEDICAL PLANS, AND HEALTH CARE PREPAYMENT PLANS Health Care Prepayment Plans § 417.838 Organization determinations....

  2. 42 CFR 417.838 - Organization determinations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 3 2013-10-01 2013-10-01 false Organization determinations. 417.838 Section 417... (CONTINUED) MEDICARE PROGRAM (CONTINUED) HEALTH MAINTENANCE ORGANIZATIONS, COMPETITIVE MEDICAL PLANS, AND HEALTH CARE PREPAYMENT PLANS Health Care Prepayment Plans § 417.838 Organization determinations....

  3. 42 CFR 417.838 - Organization determinations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Organization determinations. 417.838 Section 417... (CONTINUED) MEDICARE PROGRAM HEALTH MAINTENANCE ORGANIZATIONS, COMPETITIVE MEDICAL PLANS, AND HEALTH CARE PREPAYMENT PLANS Health Care Prepayment Plans § 417.838 Organization determinations. (a) Actions that...

  4. 42 CFR 417.838 - Organization determinations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 3 2014-10-01 2014-10-01 false Organization determinations. 417.838 Section 417... (CONTINUED) MEDICARE PROGRAM (CONTINUED) HEALTH MAINTENANCE ORGANIZATIONS, COMPETITIVE MEDICAL PLANS, AND HEALTH CARE PREPAYMENT PLANS Health Care Prepayment Plans § 417.838 Organization determinations....

  5. 42 CFR 417.838 - Organization determinations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 3 2011-10-01 2011-10-01 false Organization determinations. 417.838 Section 417... (CONTINUED) MEDICARE PROGRAM HEALTH MAINTENANCE ORGANIZATIONS, COMPETITIVE MEDICAL PLANS, AND HEALTH CARE PREPAYMENT PLANS Health Care Prepayment Plans § 417.838 Organization determinations. (a) Actions that...

  6. 42 CFR 498.24 - Reconsidered determination.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION APPEALS PROCEDURES FOR DETERMINATIONS THAT AFFECT PARTICIPATION IN THE MEDICARE PROGRAM AND FOR DETERMINATIONS THAT AFFECT THE PARTICIPATION OF ICFs/IID AND CERTAIN...

  7. 42 CFR 498.24 - Reconsidered determination.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION APPEALS PROCEDURES FOR DETERMINATIONS THAT AFFECT PARTICIPATION IN THE MEDICARE PROGRAM AND FOR DETERMINATIONS THAT AFFECT THE PARTICIPATION OF ICFs/IID AND CERTAIN...

  8. 42 CFR 498.24 - Reconsidered determination.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION APPEALS PROCEDURES FOR DETERMINATIONS THAT AFFECT PARTICIPATION IN THE MEDICARE PROGRAM AND FOR DETERMINATIONS THAT AFFECT THE PARTICIPATION OF ICFs/IID AND CERTAIN...

  9. 42 CFR 498.24 - Reconsidered determination.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION APPEALS PROCEDURES FOR DETERMINATIONS THAT AFFECT PARTICIPATION IN THE MEDICARE PROGRAM AND FOR DETERMINATIONS THAT AFFECT THE PARTICIPATION OF ICFs/MR AND CERTAIN...

  10. 42 CFR 498.24 - Reconsidered determination.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION APPEALS PROCEDURES FOR DETERMINATIONS THAT AFFECT PARTICIPATION IN THE MEDICARE PROGRAM AND FOR DETERMINATIONS THAT AFFECT THE PARTICIPATION OF ICFs/MR AND CERTAIN...

  11. 49 CFR 107.209 - Determination.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Determination. 107.209 Section 107.209 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY... the application and other relevant information received, the Chief Counsel issues a determination....

  12. 49 CFR 107.221 - Determination.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Determination. 107.221 Section 107.221 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY... Chief Counsel issues a determination. (b) The Chief Counsel may issue a waiver of preemption only...

  13. 49 CFR 107.209 - Determination.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 2 2013-10-01 2013-10-01 false Determination. 107.209 Section 107.209 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY... the application and other relevant information received, the Chief Counsel issues a determination....

  14. 49 CFR 107.221 - Determination.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 2 2011-10-01 2011-10-01 false Determination. 107.221 Section 107.221 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY... Chief Counsel issues a determination. (b) The Chief Counsel may issue a waiver of preemption only...

  15. 49 CFR 107.209 - Determination.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 2 2014-10-01 2014-10-01 false Determination. 107.209 Section 107.209 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY... the application and other relevant information received, the Chief Counsel issues a determination....

  16. 49 CFR 107.209 - Determination.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 2 2011-10-01 2011-10-01 false Determination. 107.209 Section 107.209 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY... the application and other relevant information received, the Chief Counsel issues a determination....

  17. 49 CFR 107.221 - Determination.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 2 2014-10-01 2014-10-01 false Determination. 107.221 Section 107.221 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY... Chief Counsel issues a determination. (b) The Chief Counsel may issue a waiver of preemption only...

  18. Determining a carbohydrate profile for Hansenula polymorpha.

    PubMed

    Petersen, G R

    1985-07-01

    The determination of the levels of carbohydrates in the yeast Hansenula polymorpha required the development of new analytical procedures. Existing fractionation and analytical methods were adapted to deal with the problems involved with the lysis of whole cells. Using these new procedures, the complete carbohydrates profiles of H. polymorpha and selected mutant strains were determined and shown to correlate favourably with previously published results.

  19. 45 CFR 12a.4 - Suitability determination.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... PROPERTY TO ASSIST THE HOMELESS § 12a.4 Suitability determination. (a) Suitability determination. Within 30... § 12a.6, which properties are suitable for use as facilities to assist the homeless and report its... use as a facility to assist the homeless without regard to any particular use. (c)...

  20. 45 CFR 12a.4 - Suitability determination.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... PROPERTY TO ASSIST THE HOMELESS § 12a.4 Suitability determination. (a) Suitability determination. Within 30... § 12a.6, which properties are suitable for use as facilities to assist the homeless and report its... use as a facility to assist the homeless without regard to any particular use. (c)...

  1. 45 CFR 12a.4 - Suitability determination.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... PROPERTY TO ASSIST THE HOMELESS § 12a.4 Suitability determination. (a) Suitability determination. Within 30... § 12a.6, which properties are suitable for use as facilities to assist the homeless and report its... use as a facility to assist the homeless without regard to any particular use. (c)...

  2. 45 CFR 12a.4 - Suitability determination.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... PROPERTY TO ASSIST THE HOMELESS § 12a.4 Suitability determination. (a) Suitability determination. Within 30... § 12a.6, which properties are suitable for use as facilities to assist the homeless and report its... use as a facility to assist the homeless without regard to any particular use. (c)...

  3. 45 CFR 12a.4 - Suitability determination.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PROPERTY TO ASSIST THE HOMELESS § 12a.4 Suitability determination. (a) Suitability determination. Within 30... § 12a.6, which properties are suitable for use as facilities to assist the homeless and report its... use as a facility to assist the homeless without regard to any particular use. (c)...

  4. Determination of Movement Sense in Mylonites.

    ERIC Educational Resources Information Center

    Simpson, Carol

    1986-01-01

    Describes how mylonite samples can be used to determine the sense of shear. Several sample collection techniques are presented. Criteria for shear sense determination are outlined and discussed so that they can be recognized and interpreted by students familiar with the use of a compass and a petrographic microscope. (TW)

  5. 18 CFR 286.108 - Determination.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Determination. 286.108 Section 286.108 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT... matter in issue will be determined by the Commission on the basis of the facts and arguments submitted....

  6. 40 CFR 2.207 - Class determinations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Class determinations. 2.207 Section 2.207 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PUBLIC INFORMATION Confidentiality of Business Information § 2.207 Class determinations. (a) The General Counsel may make and issue...

  7. 40 CFR 2.207 - Class determinations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Class determinations. 2.207 Section 2.207 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PUBLIC INFORMATION Confidentiality of Business Information § 2.207 Class determinations. (a) The General Counsel may make and issue...

  8. 48 CFR 846.471 - Determination authority.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Determination authority. 846.471 Section 846.471 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS CONTRACT MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance 846.471 Determination authority....

  9. 50 CFR 296.9 - Initial determination.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Initial determination. 296.9 Section 296.9 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE CONTINENTAL SHELF FISHERMEN'S CONTINGENCY FUND § 296.9 Initial determination....

  10. 50 CFR 296.11 - Final determination.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Final determination. 296.11 Section 296.11 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE CONTINENTAL SHELF FISHERMEN'S CONTINGENCY FUND § 296.11 Final determination. (a) If...

  11. Determining a carbohydrate profile for Hansenula polymorpha

    NASA Technical Reports Server (NTRS)

    Petersen, G. R.

    1985-01-01

    The determination of the levels of carbohydrates in the yeast Hansenula polymorpha required the development of new analytical procedures. Existing fractionation and analytical methods were adapted to deal with the problems involved with the lysis of whole cells. Using these new procedures, the complete carbohydrate profiles of H. polymorpha and selected mutant strains were determined and shown to correlate favourably with previously published results.

  12. 7 CFR 1738.213 - Loan determination.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 11 2013-01-01 2013-01-01 false Loan determination. 1738.213 Section 1738.213... AGRICULTURE RURAL BROADBAND ACCESS LOANS AND LOAN GUARANTEES Application Review and Underwriting § 1738.213 Loan determination. (a) If the application meets all statutory and regulatory requirements and...

  13. 7 CFR 1738.213 - Loan determination.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 11 2014-01-01 2014-01-01 false Loan determination. 1738.213 Section 1738.213... AGRICULTURE RURAL BROADBAND ACCESS LOANS AND LOAN GUARANTEES Application Review and Underwriting § 1738.213 Loan determination. (a) If the application meets all statutory and regulatory requirements and...

  14. 7 CFR 1738.213 - Loan determination.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 11 2012-01-01 2012-01-01 false Loan determination. 1738.213 Section 1738.213... AGRICULTURE RURAL BROADBAND ACCESS LOANS AND LOAN GUARANTEES Application Review and Underwriting § 1738.213 Loan determination. (a) If the application meets all statutory and regulatory requirements and...

  15. TLC determination of functionality in prepolymers

    NASA Technical Reports Server (NTRS)

    Potts, J. E., Jr.; Ashcraft, A. C.

    1973-01-01

    Application of thin-layer chromatographics provides rapid qualitative determination of functional distribution in experimental prepolymer. Functionality distribution is of fundamental importance for it determines; (1) manner in which given carboxyl-terminated prepolymer will cure and (2) physical properties of resulting product.

  16. 40 CFR 231.5 - Recommended determination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended determination. 231.5 Section 231.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c) PROCEDURES § 231.5 Recommended determination. (a) The Regional Administrator or his...

  17. Determinants of Residential Adult Education Effectiveness.

    ERIC Educational Resources Information Center

    Kafka, James J.

    Advocates of residential education have isolated three determinants of residential adult education effectiveness: isolation from the outside environment; concentration on content; and group support. This study investigated the independent and collective relationships of different levels of these determinants with cognitive gain and posttest…

  18. Determining Enzyme Activity by Radial Diffusion

    ERIC Educational Resources Information Center

    Davis, Bill D.

    1977-01-01

    Discusses advantages of radial diffusion assay in determining presence of enzyme and/or rough approximation of amount of enzyme activities. Procedures are included for the preparation of starch-agar plates, and the application and determination of enzyme. Techniques using plant materials (homogenates, tissues, ungerminated embryos, and seedlings)…

  19. 12 CFR 404.8 - Initial determination.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Disclosure of Records Under the Freedom of Information Act. § 404.8 Initial determination. (a) Authority to..., review, and the initial determination. (b) Referrals to other government agencies. A requested record in... disclose the requested records and shall inform the requester of any fee payable under § 404.9. (2)...

  20. 18 CFR 286.108 - Determination.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Determination. 286.108 Section 286.108 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT... matter in issue will be determined by the Commission on the basis of the facts and arguments submitted....

  1. 18 CFR 349.6 - Determination.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Determination. 349.6 Section 349.6 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT... PROPOSED REMEDIES § 349.6 Determination. If no formal hearing is had the matter in issue will be...

  2. 18 CFR 349.6 - Determination.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Determination. 349.6 Section 349.6 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT... PROPOSED REMEDIES § 349.6 Determination. If no formal hearing is had the matter in issue will be...

  3. 18 CFR 286.108 - Determination.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Determination. 286.108 Section 286.108 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT... matter in issue will be determined by the Commission on the basis of the facts and arguments submitted....

  4. Framing the Future: Self-Determination

    ERIC Educational Resources Information Center

    Wehmeyer, Michael L.

    2015-01-01

    There is an established and still-growing evidence base that promoting self-determination has positive school and post-school benefits for students with disabilities, and yet efforts to do so remain sporadic, at best. This article examines the evidence that promoting self-determination is critically important for students with disabilities,…

  5. Maneuver Estimation Model for Geostationary Orbit Determination

    DTIC Science & Technology

    2006-06-01

    MODEL FOR GEOSTATIONARY ORBIT DETERMINATION THESIS Presented to the Faculty Department of Aeronautics and Astronautics Graduate...FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED. AFIT/GA/ENY/06-J01 MANEUVER ESTIMATION MODEL FOR GEOSTATIONARY ORBIT DETERMINATION...used to model the relative motion of a geostationary satellite about its intended location and a nonlinear least squares algorithm was developed to

  6. Linear determining equations for differential constraints

    SciTech Connect

    Kaptsov, O V

    1998-12-31

    A construction of differential constraints compatible with partial differential equations is considered. Certain linear determining equations with parameters are used to find such differential constraints. They generalize the classical determining equations used in the search for admissible Lie operators. As applications of this approach equations of an ideal incompressible fluid and non-linear heat equations are discussed.

  7. ZWY Sex Determination in Xenopus tropicalis

    EPA Science Inventory

    Most vertebrate species with described genetic sex determination are either male (XY) or female (ZW) heterogametic. To date, studies with Xenopus species indicate that members of this genus operate under a ZW sex determination system. We used two different approaches and demonst...

  8. 11 CFR 9409.9 - Final determination.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 11 Federal Elections 1 2011-01-01 2011-01-01 false Final determination. 9409.9 Section 9409.9 Federal Elections ELECTION ASSISTANCE COMMISSION TESTIMONY BY COMMISSION EMPLOYEES RELATING TO OFFICIAL INFORMATION AND PRODUCTION OF OFFICIAL RECORDS IN LEGAL PROCEEDINGS § 9409.9 Final determination. The...

  9. 11 CFR 9409.9 - Final determination.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Final determination. 9409.9 Section 9409.9 Federal Elections ELECTION ASSISTANCE COMMISSION TESTIMONY BY COMMISSION EMPLOYEES RELATING TO OFFICIAL INFORMATION AND PRODUCTION OF OFFICIAL RECORDS IN LEGAL PROCEEDINGS § 9409.9 Final determination. The...

  10. 11 CFR 9409.9 - Final determination.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 11 Federal Elections 1 2012-01-01 2012-01-01 false Final determination. 9409.9 Section 9409.9 Federal Elections ELECTION ASSISTANCE COMMISSION TESTIMONY BY COMMISSION EMPLOYEES RELATING TO OFFICIAL INFORMATION AND PRODUCTION OF OFFICIAL RECORDS IN LEGAL PROCEEDINGS § 9409.9 Final determination. The...

  11. 11 CFR 9409.9 - Final determination.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 11 Federal Elections 1 2013-01-01 2012-01-01 true Final determination. 9409.9 Section 9409.9 Federal Elections ELECTION ASSISTANCE COMMISSION TESTIMONY BY COMMISSION EMPLOYEES RELATING TO OFFICIAL INFORMATION AND PRODUCTION OF OFFICIAL RECORDS IN LEGAL PROCEEDINGS § 9409.9 Final determination. The...

  12. 11 CFR 9409.9 - Final determination.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 11 Federal Elections 1 2014-01-01 2014-01-01 false Final determination. 9409.9 Section 9409.9 Federal Elections ELECTION ASSISTANCE COMMISSION TESTIMONY BY COMMISSION EMPLOYEES RELATING TO OFFICIAL INFORMATION AND PRODUCTION OF OFFICIAL RECORDS IN LEGAL PROCEEDINGS § 9409.9 Final determination. The...

  13. Determination of equivalent weight of amines

    SciTech Connect

    Selig, W.S.

    1987-01-08

    A procedure for the determination of equivalent weight of amines is described. This procedure is based on an acid-base reaction performed in glacial acetic acid. The sum of primary, secondary, and tertiary amines are determined by titration with standard perchloric acid in glacial acetic acid. 1 ref.

  14. Determination Of Ph Including Hemoglobin Correction

    DOEpatents

    Maynard, John D.; Hendee, Shonn P.; Rohrscheib, Mark R.; Nunez, David; Alam, M. Kathleen; Franke, James E.; Kemeny, Gabor J.

    2005-09-13

    Methods and apparatuses of determining the pH of a sample. A method can comprise determining an infrared spectrum of the sample, and determining the hemoglobin concentration of the sample. The hemoglobin concentration and the infrared spectrum can then be used to determine the pH of the sample. In some embodiments, the hemoglobin concentration can be used to select an model relating infrared spectra to pH that is applicable at the determined hemoglobin concentration. In other embodiments, a model relating hemoglobin concentration and infrared spectra to pH can be used. An apparatus according to the present invention can comprise an illumination system, adapted to supply radiation to a sample; a collection system, adapted to collect radiation expressed from the sample responsive to the incident radiation; and an analysis system, adapted to relate information about the incident radiation, the expressed radiation, and the hemoglobin concentration of the sample to pH.

  15. How Darwinian reductionism refutes genetic determinism.

    PubMed

    Rosoff, Philip M; Rosenberg, Alex

    2006-03-01

    Genetic determinism labels the morally problematical claim that some socially significant traits, traits we care about, such as sexual orientation, gender roles, violence, alcoholism, mental illness, intelligence, are largely the results of the operation of genes and not much alterable by environment, learning or other human intervention. Genetic determinism does not require that genes literally fix these socially significant traits, but rather that they constrain them within narrow channels beyond human intervention. In this essay we analyze genetic determinism in light of what is now known about the inborn error of metabolism phenylketonuria (PKU), which has for so long been the poster child 'simple' argument in favor of some form of genetic determinism. We demonstrate that this case proves the exact opposite of what it has been proposed to support and provides a strong refutation of genetic determinism in all its guises.

  16. TDRS orbit determination by radio interferometry

    NASA Technical Reports Server (NTRS)

    Pavloff, Michael S.

    1994-01-01

    In support of a NASA study on the application of radio interferometry to satellite orbit determination, MITRE developed a simulation tool for assessing interferometry tracking accuracy. The Orbit Determination Accuracy Estimator (ODAE) models the general batch maximum likelihood orbit determination algorithms of the Goddard Trajectory Determination System (GTDS) with the group and phase delay measurements from radio interferometry. ODAE models the statistical properties of tracking error sources, including inherent observable imprecision, atmospheric delays, clock offsets, station location uncertainty, and measurement biases, and through Monte Carlo simulation, ODAE calculates the statistical properties of errors in the predicted satellites state vector. This paper presents results from ODAE application to orbit determination of the Tracking and Data Relay Satellite (TDRS) by radio interferometry. Conclusions about optimal ground station locations for interferometric tracking of TDRS are presented, along with a discussion of operational advantages of radio interferometry.

  17. The GEOS-3 orbit determination investigation

    NASA Technical Reports Server (NTRS)

    Pisacane, V. L.; Eisner, A.; Yionoulis, S. M.; Mcconahy, R. J.; Black, H. D.; Pryor, L. L.

    1978-01-01

    The nature and improvement in satellite orbit determination when precise altimetric height data are used in combination with conventional tracking data was determined. A digital orbit determination program was developed that could singly or jointly use laser ranging, C-band ranging, Doppler range difference, and altimetric height data. Two intervals were selected and used in a preliminary evaluation of the altimeter data. With the data available, it was possible to determine the semimajor axis and eccentricity to within several kilometers, in addition to determining an altimeter height bias. When used jointly with a limited amount of either C-band or laser range data, it was shown that altimeter data can improve the orbit solution.

  18. The determinants of the antibiotic resistance process

    PubMed Central

    Franco, Beatriz Espinosa; Altagracia Martínez, Marina; Sánchez Rodríguez, Martha A; Wertheimer, Albert I

    2009-01-01

    Background: The use of antibiotic drugs triggers a complex interaction involving many biological, sociological, and psychological determinants. Resistance to antibiotics is a serious worldwide problem which is increasing and has implications for morbidity, mortality, and health care both in hospitals and in the community. Objectives: To analyze current research on the determinants of antibiotic resistance and comprehensively review the main factors in the process of resistance in order to aid our understanding and assessment of this problem. Methods: We conducted a MedLine search using the key words “determinants”, “antibiotic”, and “antibiotic resistance” to identify publications between 1995 and 2007 on the determinants of antibiotic resistance. Publications that did not address the determinants of antibiotic resistance were excluded. Results: The process and determinants of antibiotic resistance are described, beginning with the development of antibiotics, resistance and the mechanisms of resistance, sociocultural determinants of resistance, the consequences of antibiotic resistance, and alternative measures proposed to combat antibiotic resistance. Conclusions: Analysis of the published literature identified the main determinants of antibiotic resistance as irrational use of antibiotics in humans and animal species, insufficient patient education when antibiotics are prescribed, lack of guidelines for treatment and control of infections, lack of scientific information for physicians on the rational use of antibiotics, and lack of official government policy on the rational use of antibiotics in public and private hospitals. PMID:21694883

  19. Development of Methods for Determination of Aflatoxins.

    PubMed

    Xie, Lijuan; Chen, Min; Ying, Yibin

    2016-12-09

    Aflatoxins can cause damage to the health of humans and animals. Several institutions around the world have established regulations to limit the levels of aflatoxins in food, and numerous analytical methods have been extensively developed for aflatoxin determination. This review covers the currently used analytical methods for the determination of aflatoxins in different food matrices, which includes sampling and sample preparation, sample pretreatment methods including extraction methods and purification methods of aflatoxin extracts, separation and determination methods. Validation for analysis of aflatoxins and safety considerations and precautions when doing the experiments are also discussed.

  20. Determining Price Reasonableness in Federal ESPCs

    SciTech Connect

    Shonder, J.A.

    2005-03-08

    This document reports the findings and implementation recommendations of the Price Reasonableness Working Group to the Federal ESPC Steering Committee. The working group was formed to address concerns of agencies and oversight organizations related to pricing and fair and reasonable price determination in federal energy savings performance contracts (ESPCs). This report comprises the working group's recommendations and is the proposed draft of a training curriculum on fair and reasonable price determination for users of federal ESPCs. The report includes: (1) A review of federal regulations applicable to determining price reasonableness of federal ESPCs (section 2), (2) Brief descriptions of the techniques described in Federal Acquisition Regulations (FAR) 15.404-1 and their applicability to ESPCs (section 3), and (3) Recommended strategies and procedures for cost-effectively completing price reasonableness determinations (sections 4). Agencies have struggled with fair and reasonable price determinations in their ESPCs primarily because this alternative financing vehicle is relatively new and relatively rare in the federal sector. The methods of determining price reasonableness most familiar to federal contracting officers (price competition based on the government's design and specifications, in particular) are generally not applicable to ESPCs. The regulatory requirements for determining price reasonableness in federal ESPCs have also been misunderstood, as federal procurement professionals who are inexperienced with ESPCs are further confused by multiple directives, including Executive Order 13123, which stresses life-cycle cost-effectiveness. Uncertainty about applicable regulations and inconsistent practice and documentation among agencies have fueled claims that price reasonableness determinations have not been sufficiently rigorous in federal ESPCs or that the prices paid in ESPCs are generally higher than the prices paid for similar goods and services

  1. A Multichannel Bioluminescence Determination Platform for Bioassays.

    PubMed

    Kim, Sung-Bae; Naganawa, Ryuichi

    2016-01-01

    The present protocol introduces a multichannel bioluminescence determination platform allowing a high sample throughput determination of weak bioluminescence with reduced standard deviations. The platform is designed to carry a multichannel conveyer, an optical filter, and a mirror cap. The platform enables us to near-simultaneously determine ligands in multiple samples without the replacement of the sample tubes. Furthermore, the optical filters beneath the multichannel conveyer are designed to easily discriminate colors during assays. This optical system provides excellent time- and labor-efficiency to users during bioassays.

  2. Polarographic determination of tungsten in rocks

    USGS Publications Warehouse

    Reichen, L.E.

    1954-01-01

    This work was undertaken to develop a simpler and faster method than the classical gravimetric procedure for the determination of tungsten in rocks and ores. A new polarographic wave of tungsten is obtained in a supporting electrolyte of dilute hydrochloric acid containing tartrate ion. This permits the determination of tungsten both rapidly and accurately. No precipitation of the tungsten is necessary, and only the iron need be separated from the tungsten. The accuracy is within the limits of a polarographic procedure; comparison of polarographic and gravimetric results is given. The method reduces appreciably the amount of time ordinarily consumed in determination of tungsten.

  3. Woodcock age and sex determination from wings

    USGS Publications Warehouse

    Martin, F.W.

    1964-01-01

    Age of woodcock (Philohela minor) can be accurately determined throughout the year by differences in pattern, color, and wear of secondary feathers. Immature woodcock retain most secondaries during the postjuvenal molt that begins in July or August and ends in October. In contrast, subadults (first-year adults) and older woodcock molt all secondaries during the postnuptial molt beginning in June or July and ending in October. Retention of juvenal secondaries by immatures and molt of these feathers by adults form the basis for age determination. Sex of woodcock can be accurately determined by width of the outer three primaries, which are conspicuously narrower on males.

  4. Determining Polarities Of Distant Lightning Strokes

    NASA Technical Reports Server (NTRS)

    Blakeslee, Richard J.; Brook, Marx

    1990-01-01

    Method for determining polarities of lightning strokes more than 400 km away. Two features of signal from each stroke correlated. New method based on fact each stroke observed thus far for which polarity determined unambiguously, initial polarity of tail same as polarity of initial deflection before initial-deflection signal altered by propagation effects. Receiving station equipped with electric-field-change antenna coupled to charge amplifier having time constant of order of 1 to 10 seconds. Output of amplifier fed to signal-processing circuitry, which determines initial polarity of tail.

  5. Kinetic determination of selenium in biological material

    SciTech Connect

    Efremenko, O.A.; Krasnyuk, I.I.; Kudrin, A.N.; Rudenko, B.A.

    1986-05-10

    A very promising method for selenium determination is a kinetic analytical procedure that combines the simplicity and availability of physical instrumentation with a low analyte detection limit. This paper reports a modification of the method to enable the determination of selenium in rat blood and involves decomposing the sample with a mixture of nitric and perchloric acids, separation of the selenium (IV) from other decomposition products, and quantitatively determining selenium by the described kinetic method using the indicator reaction of iron (II) edetate oxidation by sodium nitrate.

  6. Does turbulence determine the initial mass function?

    NASA Astrophysics Data System (ADS)

    Liptai, David; Price, Daniel J.; Wurster, James; Bate, Matthew R.

    2017-02-01

    We test the hypothesis that the initial mass function (IMF) is determined by the density probability distribution function (PDF) produced by supersonic turbulence. We compare 14 simulations of star cluster formation in 50 M⊙ molecular cloud cores where the initial turbulence contains either purely solenoidal or purely compressive modes, in each case resolving fragmentation to the opacity limit to determine the resultant IMF. We find statistically indistinguishable IMFs between the two sets of calculations, despite a factor of 2 difference in the star formation rate and in the standard deviation of log (ρ). This suggests that the density PDF, while determining the star formation rate, is not the primary driver of the IMF.

  7. Determination of microquantities of hexabromocyclododecane in air

    SciTech Connect

    Paama, L.A.; Kheinaste, T.A.; Kokk, K.Y.; Solov'eva, E.V.; Vostrikav, V.I.

    1985-08-01

    The authors develop and present a simple and accessible method of determining microquantities of hexabromocyclododecane (HBCD) from the air to be analyzed, and they remove elementary bromine. The analytical procedure is described and tables present the results of the experiments. They found that acetone and ethanol did not interfere with the determination of HBCD in air. It was established that in the method of collection of air samples described, hydrogen bromide and elementary bromide are not retained by silica gel and also do not interfere with the determination of HBCD.

  8. 7 CFR 47.49 - Determinations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE MARKETING OF PERISHABLE AGRICULTURAL COMMODITIES RULES OF PRACTICE UNDER THE PERISHABLE AGRICULTURAL COMMODITIES ACT Rules Applicable to the Determination As to Whether...

  9. Soft Determinism plus Awareness Equals Shared Responsibility

    ERIC Educational Resources Information Center

    Rousseve, Ronald J.

    1971-01-01

    This article seeks to present a viable resolution of one of the perennial ideological issues in counseling: determinism versus human freedom. The dilemma has bearing on the related professional issue of client and counselor responsibility. (Author)

  10. Immigration as a social determinant of health.

    PubMed

    Castañeda, Heide; Holmes, Seth M; Madrigal, Daniel S; Young, Maria-Elena DeTrinidad; Beyeler, Naomi; Quesada, James

    2015-03-18

    Although immigration and immigrant populations have become increasingly important foci in public health research and practice, a social determinants of health approach has seldom been applied in this area. Global patterns of morbidity and mortality follow inequities rooted in societal, political, and economic conditions produced and reproduced by social structures, policies, and institutions. The lack of dialogue between these two profoundly related phenomena-social determinants of health and immigration-has resulted in missed opportunities for public health research, practice, and policy work. In this article, we discuss primary frameworks used in recent public health literature on the health of immigrant populations, note gaps in this literature, and argue for a broader examination of immigration as both socially determined and a social determinant of health. We discuss priorities for future research and policy to understand more fully and respond appropriately to the health of the populations affected by this global phenomenon.

  11. Final Determination - signed November 23, 1990

    EPA Pesticide Factsheets

    Final determination of the U.S. EPA’s Assistant Administrator for Water pursuant to section 404(c) of the Clean Water Act concerning the Two Forks water supply impoundments in Jefferson and Douglas counties, Colorado.

  12. Thirteenth satellite of Jupiter. [orbit determination

    NASA Technical Reports Server (NTRS)

    Kowal, C. T.; Aksnes, K.; Marsden, B. G.; Roemer, E.

    1975-01-01

    The discovery, observations, and attempts to determine the orbit of Jupiter XIII are described. It is found that the orbit is very similar to the orbits of Jupiter VI, VII, and X. An ephemeris is provided for the 1975 opposition.

  13. Isotope ratio determination in boron analysis.

    PubMed

    Sah, R N; Brown, P H

    1998-01-01

    Traditionally, boron (B) isotope ratios have been determined using thermal ionization mass spectrometry (TIMS) and, to some extent, secondary ion mass spectrometry (SIMS). Both TIMS and SIMS use a high-resolution mass analyzer, but differ in analyte ionization methods. TIMS uses electrons from a hot filament, whereas SIMS employs an energetic primary ion beam of Ga+, Cs+, or O- for analyte ionization. TIMS can be used in negative or positive ion modes with high sensitivity and precision of B isotope ratio determination. However, isobaric interferences may be a problem, if the sample is not well purified and/or memory of the previous sample is not removed. Time-consuming sample preparation, analyte (B) purification, and sample determination processes limit the applications of TIMS for routine analyses. SIMS can determine B and its isotope ratio in intact solid samples without destroying them, but has poorer resolution and sensitivity than TIMS, and is difficult to standardize for biological samples. Development of plasma-source mass spectrometry (MS) enabled the determination of B concentration and isotope ratio without requiring sample purification. Commonly used plasma-source MS uses an Ar inductively coupled plasma (ICP) as an ionization device interfaced to a low-resolution quadrupole mass analyzer. The quadrupole ICP-MS is less precise than TIMS and SIMS, but is a popular method for B isotope ratio determination because of its speed and convenience. B determination by ICP-MS suffers no spectroscopic interferences. However, sample matrices, memory effects, and some instrument parameters may affect the accuracy and precision of B isotope ratio determination if adequate precautions are not taken. New generations of plasma-source MS instruments using high-resolution mass analyzers provide better sensitivity and precision than the currently used quadrupole ICP-MS. Because of the convenience and high sample throughput, the high-resolution ICP-MS is expected to be the

  14. 7 CFR 1437.403 - Determining payments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... producer's share; (b) Dividing the result from paragraph (a) of this section by the carrying capacity or adjusted per day carrying capacity established for the specific acreage, as determined by CCC;...

  15. 7 CFR 1437.403 - Determining payments.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... producer's share; (b) Dividing the result from paragraph (a) of this section by the carrying capacity or adjusted per day carrying capacity established for the specific acreage, as determined by CCC;...

  16. 7 CFR 1437.403 - Determining payments.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... producer's share; (b) Dividing the result from paragraph (a) of this section by the carrying capacity or adjusted per day carrying capacity established for the specific acreage, as determined by CCC;...

  17. 7 CFR 1437.403 - Determining payments.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... producer's share; (b) Dividing the result from paragraph (a) of this section by the carrying capacity or adjusted per day carrying capacity established for the specific acreage, as determined by CCC;...

  18. 7 CFR 1437.403 - Determining payments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... producer's share; (b) Dividing the result from paragraph (a) of this section by the carrying capacity or adjusted per day carrying capacity established for the specific acreage, as determined by CCC;...

  19. 27 CFR 19.346 - Determining obscuration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... water may be added to a lot of spirits to be bottled for which the determination of proof obscuration is... chapter, the proof obscuration of spirits to be bottled on the basis of a representative sample taken...

  20. 27 CFR 19.346 - Determining obscuration.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... water may be added to a lot of spirits to be bottled for which the determination of proof obscuration is... chapter, the proof obscuration of spirits to be bottled on the basis of a representative sample taken...

  1. 27 CFR 19.346 - Determining obscuration.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... water may be added to a lot of spirits to be bottled for which the determination of proof obscuration is... chapter, the proof obscuration of spirits to be bottled on the basis of a representative sample taken...

  2. Final Determination - signed August 31, 2008

    EPA Pesticide Factsheets

    Final Determination of the U.S. EPA’s Assistant Administrator for Water pursuant to Section 404(c) of the Clean Water Act concerning the proposed Yazoo Backwater area pumps project, Issaquena county, Mississippi.

  3. Fuglede–Kadison determinant: theme and variations

    PubMed Central

    de la Harpe, Pierre

    2013-01-01

    We review the definition of determinants for finite von Neumann algebras, due to Fuglede and Kadison [Fuglede B, Kadison R (1952) Ann Math 55:520–530], and a generalization for appropriate groups of invertible elements in Banach algebras, from a paper by Skandalis and the author (1984). After some discussion of K-theory and Whitehead torsion, we indicate the relevance of these determinants to the study of -torsion in topology. Contents are as follows:1. The classical setting.2. On von Neumann algebras and traces.3. Fuglede–Kadison determinant for finite von Neumann algebras.4. Motivating question.5. Brief reminder of , , , and Bott periodicity.6. Revisiting the Fuglede–Kadison and other determinants.7. On Whitehead torsion.8. A few lines on -torsion. PMID:24082099

  4. Functional determinants from Wronski Green functions

    NASA Astrophysics Data System (ADS)

    Kleinert, H.; Chervyakov, A.

    1999-11-01

    A general technique is developed for calculating functional determinants of second-order differential operators with Dirichlet, periodic, and antiperiodic boundary conditions, without the knowledge of spectral properties. As an example, we give explicit formulas for a harmonic oscillator with an arbitrary time-dependent frequency, where our result is a generalization of the Gel'fand-Yaglom famous formula for Dirichlet boundary conditions. Our technique is based on the Wronski's construction of Green functions, which does not require spectral knowledge. Our final formula expresses the ratios of functional determinants in terms of an ordinary 2×2 determinant of a constant matrix constructed from two linearly independent solutions of the homogeneous differential equations associated with second-order differential operators. For ratios of determinants encountered in semiclassical fluctuations around a classical solution, the result can further be expressed in terms of the classical solution. Special properties of operators with a zero mode are exhibited.

  5. 27 CFR 19.346 - Determining obscuration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... water may be added to a lot of spirits to be bottled for which the determination of proof obscuration is... chapter, the proof obscuration of spirits to be bottled on the basis of a representative sample taken...

  6. Demagnetization using a determined estimated magnetic state

    DOEpatents

    Denis, Ronald J; Makowski, Nathanael J

    2015-01-13

    A method for demagnetizing comprising positioning a core within the electromagnetic field generated by a first winding until the generated first electrical current is not substantially increasing, thereby determining a saturation current. A second voltage, having the opposite polarity, is then applied across the first winding until the generated second electrical current is approximately equal to the magnitude of the determined saturation current. The maximum magnetic flux within the core is then determined using the voltage across said first winding and the second current. A third voltage, having the opposite polarity, is then applied across the first winding until the core has a magnetic flux equal to approximately half of the determined maximum magnetic flux within the core.

  7. Determining the Population Size of Pond Phytoplankton.

    ERIC Educational Resources Information Center

    Hummer, Paul J.

    1980-01-01

    Discusses methods for determining the population size of pond phytoplankton, including water sampling techniques, laboratory analysis of samples, and additional studies worthy of investigation in class or as individual projects. (CS)

  8. A Quantitative Gas Chromatographic Ethanol Determination.

    ERIC Educational Resources Information Center

    Leary, James J.

    1983-01-01

    Describes a gas chromatographic experiment for the quantitative determination of volume percent ethanol in water ethanol solutions. Background information, procedures, and typical results are included. Accuracy and precision of results are both on the order of two percent. (JN)

  9. Goddard trajectory determination subsystem: Mathematical specifications

    NASA Technical Reports Server (NTRS)

    Wagner, W. E. (Editor); Velez, C. E. (Editor)

    1972-01-01

    The mathematical specifications of the Goddard trajectory determination subsystem of the flight dynamics system are presented. These specifications include the mathematical description of the coordinate systems, dynamic and measurement model, numerical integration techniques, and statistical estimation concepts.

  10. Final Determination - signed October 16, 1985

    EPA Pesticide Factsheets

    Fianl Determination of the U.S. EPA's Assistant Administrator for External Affairs concerning the Bayou Aux Carpes site in Jefferson Parish, Louisiana pursuant to Section 404(c) of the Clean Water Act.

  11. Determinant of securitization asset pricing in Malaysia

    NASA Astrophysics Data System (ADS)

    Bakri, M. H.; Ali, R.; Ismail, S.; Sufian, F.; Baharom, A. H.

    2014-12-01

    Malaysian firms have been reported involve in Asset Back Securities since 1986s where Cagamas is a pioneer. This research aims to examine the factor influencing primary market spread. Least square method and regression analysis are applied for the study period 2004-2012. The result shows one determinants in internal regression model and three determinants in external regression influence or contribute to the primary market spread and are statistically significant in developing the securitization in Malaysia. It can be concluded that transaction size significantly contribute to the determinant primary market spread in internal regression model while liquidity, transaction size and crisis is significant in both regression model. From five hypotheses, three hypotheses support that the determinants have a relationship with primary market spread.

  12. 7 CFR 51.1416 - Optional determinations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) Kernel moisture content. The sample of pecans for determination of kernel moisture content shall be... air-oven or other methods or devices which give equivalent results shall be used for moisture...

  13. Cone Penetrometer N Factor Determination Testing Results

    SciTech Connect

    Follett, Jordan R.

    2014-03-05

    This document contains the results of testing activities to determine the empirical 'N Factor' for the cone penetrometer in kaolin clay simulant. The N Factor is used to releate resistance measurements taken with the cone penetrometer to shear strength.

  14. Rapid analytical determination of glutaraldehyde concentrations

    NASA Technical Reports Server (NTRS)

    Frigerio, N. A.; Shaw, M. H.

    1971-01-01

    Technique utilizes the iodimetric procedure which adds unknown excess of bisulfite to glutaraldehyde /GA/ then titrates unreacted bisulfite with standard iodine isotope to determine GA concentrations. Technique may interest microscopists, food researchers, biochemical or medical laboratories, and drug manufacturers.

  15. Final Determination - signed March 1, 1990

    EPA Pesticide Factsheets

    Final Determination of the U.S. Environmental Protection Agency's Assistant Administrator for Water pursuant to Section 404(c) of the Clean Water Act concerning the proposed Big River water supply impoundment in Kent county, RI.

  16. Final Determination - signed March 21, 1988

    EPA Pesticide Factsheets

    Information about final determination of the U.S. EPA's Assistant Administrator for water, concerning wetlands owned by the Russo Development Corporation in Carlstadt, New Jersey pursuant to section 404(c) of the Clean Water Act.

  17. Simulation training in brain death determination.

    PubMed

    Hocker, Sara; Wijdicks, Eelco F M

    2015-04-01

    Skill in the determination of brain death is traditionally acquired during training in an apprenticeship model. Brain death is not frequently determined, and thus exposure to the techniques used is marginal. Brain death is therefore ideally suited for competency-based education models such as simulation. Simulation can ensure that all trainees have direct experience in brain death determination irrespective of their specialty, program design, or institutional protocol. In this review, the authors discuss the advantages and barriers to simulation and how to develop simulation scenarios for instruction in the determination of brain death. Future research should focus on validation of brain death simulation methods and assessment tools as well as the impact of simulation on performance in clinical practice.

  18. ISS Update: Attitude Determination and Control Officer

    NASA Video Gallery

    NASA Public Affairs Officer Dan Huot talks with Attitude Determination and Control Officer (ADCO) flight controller Ann Esbeck in the Mission Control Center at Johnson Space Center. They discuss th...

  19. Simultaneous Determination of Amlodipine and Valsartan

    PubMed Central

    Mohamed, Nashwah Gadallah

    2011-01-01

    A spectrophotometric method was developed for simultaneous determination of amlodipine (Aml) and valsartan (Val) without previous separation. In this method amlodipine in methanolic solution was determined using zero order UV spectrophotometry by measuring its absorbency at 360.5 nm without any interference from valsartan. Valsartan spectrum in zero order is totally overlapped with that of amlodipine. First, second and third derivative could not resolve the overlapped peaks. The first derivative of the ratio spectra technique was applied for the measurement of valsartan. The ratio spectrum was obtained by dividing the absorption spectrum of the mixture by that of amlodipine, so that the concentration of valsartan could be determined from the first derivative of the ratio spectrum at 290 nm. Quantification limits of amlodipine and valsartan were 10–80 μg/ml and 20–180 μg/ml respectively. The method was successfully applied for the quantitative determination of both drugs in bulk powder and pharmaceutical formulation. PMID:21918600

  20. 7 CFR 1499.3 - Eligibility determination.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... framework to implement the activities the entity proposes to carry out under FFPr. In order to determine..., FAS may consider the entity's previous compliance or noncompliance with the provisions of this...

  1. Substrates and method for determining enzymes

    DOEpatents

    Smith, R.E.; Bissell, E.R.

    1981-10-13

    A method is disclosed for determining the presence of an enzyme in a biological fluid, which includes the steps of contacting the fluid with a synthetic chromogenic substrate, which is an amino acid derivative of 7-amino-4-trifluoromethylcoumarin; incubating the substrate-containing fluid to effect enzymatic hydrolysis; and fluorometrically determining the presence of the free 7-amino-4-trifluoromethylcoumarin chromophore in the hydrolyzate. No Drawings

  2. Computer simulation of the threshold sensitivity determinations

    NASA Technical Reports Server (NTRS)

    Gayle, J. B.

    1974-01-01

    A computer simulation study was carried out to evaluate various methods for determining threshold stimulus levels for impact sensitivity tests. In addition, the influence of a number of variables (initial stimulus level, particular stimulus response curve, and increment size) on the apparent threshold values and on the corresponding population response levels was determined. Finally, a critical review of previous assumptions regarding the stimulus response curve for impact testing is presented in the light of the simulation results.

  3. Substrates and method for determining enzymes

    DOEpatents

    Smith, Robert E.; Bissell, Eugene R.

    1981-01-01

    A method is disclosed for determining the presence of an enzyme in a biological fluid, which includes the steps of contacting the fluid with a synthetic chromogenic substrate, which is an amino acid derivative of 7-amino-4-trifluoromethylcoumarin; incubating the substrate-containing fluid to effect enzymatic hydrolysis; and fluorometrically determining the presence of the free 7-amino-4-trifluoromethylcoumarin chromophore in the hydrolyzate.

  4. Quantitative determination of atmospheric hydroperoxyl radical

    DOEpatents

    Springston, Stephen R.; Lloyd, Judith; Zheng, Jun

    2007-10-23

    A method for the quantitative determination of atmospheric hydroperoxyl radical comprising: (a) contacting a liquid phase atmospheric sample with a chemiluminescent compound which luminesces on contact with hydroperoxyl radical; (b) determining luminescence intensity from the liquid phase atmospheric sample; and (c) comparing said luminescence intensity from the liquid phase atmospheric sample to a standard luminescence intensity for hydroperoxyl radical. An apparatus for automating the method is also included.

  5. Spectrophotometric determination of fluorine in silicate rocks

    USGS Publications Warehouse

    Peck, L.C.; Smith, V.C.

    1964-01-01

    The rock powder is sintered with a sodium carbonate flux containing zinc oxide and magnesium carbonate, the sinter-cake leached with water and the resulting solution filtered. Fluorine is separated from the acidified filtrate by steam distillation and determined spectrophotometrically by means of a zirconium-SPADNS reagent. If a multiple-unit distillation apparatus is used, 12 determinations can be completed per man-day. ?? 1964.

  6. Determinants of injuries in passenger vessel accidents.

    PubMed

    Yip, Tsz Leung; Jin, Di; Talley, Wayne K

    2015-09-01

    This paper investigates determinants of crew and passenger injuries in passenger vessel accidents. Crew and passenger injury equations are estimated for ferry, ocean cruise, and river cruise vessel accidents, utilizing detailed data of individual vessel accidents that were investigated by the U.S. Coast Guard during the time period 2001-2008. The estimation results provide empirical evidence (for the first time in the literature) that crew injuries are determinants of passenger injuries in passenger vessel accidents.

  7. [Pitfalls in the determination of distance glasses].

    PubMed

    Lachenmayr, B

    2011-04-01

    The correct determination of distance glasses depends on a correct objective refraction and a subject determination of power and axis of a possible astigmatism in both a coarse and fine manner. In suitable cases a binocular fine refraction under polarized conditions with a red-green test should be performed. Special considerations have to be taken into account in cases of high unilateral congenital or acquired astigmatism as well as in case of congenital or acquired anisometropia or aniseiconia.

  8. A Method to determine lysine acetylation stoichiometries

    SciTech Connect

    Nakayasu, Ernesto S.; Wu, Si; Sydor, Michael A.; Shukla, Anil K.; Weitz, Karl K.; Moore, Ronald J.; Hixson, Kim K.; Kim, Jong Seo; Petyuk, Vladislav A.; Monroe, Matthew E.; Pasa-Tolic, Ljiljana; Qian, Weijun; Smith, Richard D.; Adkins, Joshua N.; Ansong, Charles

    2014-07-21

    A major bottleneck to fully understanding the functional aspects of lysine acetylation is the lack of stoichiometry information. Here we describe a mass spectrometry method using a combination of isotope labeling and detection of a diagnostic fragment ion to determine the stoichiometry of lysine acetylation on proteins globally. Using this technique, we determined the modification occupancy on hundreds of acetylated peptides from cell lysates and cross-validated the measurements via immunoblotting.

  9. Porosity determination of thermal barrier coatings

    NASA Technical Reports Server (NTRS)

    Van Roode, Mark; Beardsley, Brad

    1988-01-01

    Coating porosity is believed to be a critical factor for the thermal conductivity of thermal barrier coatings (TBCs). A number of different techniques have been used to determine the porosities of thermal barrier coatings for diesel applications as part of a NASA/DOE sponsored study. A comparison is made between methods based on water immersion, optical microscopy, eddy current thickness measurements, and Archimedes principle for TBC porosity determination.

  10. Attitude Determination Using Two Vector Measurements

    NASA Technical Reports Server (NTRS)

    Markley, F. Landis

    1998-01-01

    Many spacecraft attitude determination methods use exactly two vector measurements. The two vectors are typically the unit vector to the Sun and the Earth's magnetic field vector for coarse "sun-mag" attitude determination or unit vectors to two stars tracked by two star trackers for fine attitude determination. TRIAD, the earliest published algorithm for determining spacecraft attitude from two vector measurements, has been widely used in both ground-based and onboard attitude determination. Later attitude determination methods have been based on Wahba's optimality criterion for n arbitrarily weighted observations. The solution of Wahba's problem is somewhat difficult in the general case, but there is a simple closed-form solution in the two-observation case. This solution reduces to the TRIAD solution for certain choices of measurement weights. This paper presents and compares these algorithms as well as sub-optimal algorithms proposed by Bar-Itzhack, Harman, and Reynolds. Some new results will be presented, but the paper is primarily a review and tutorial.

  11. Reclaiming Self-Determination from the Indian Self-Determination and Education Assistance Act of 1975

    ERIC Educational Resources Information Center

    Wilson, Michael D.

    2012-01-01

    This paper examines the way the term "self-determination" is used in the Indian Self-Determination and Education Assistance Act of 1975. Its main thesis is that the Act does not in fact offer tribal governments self-determination, but instead reaffirms old power configurations that go back to the Indian Reorganization Act of 1934.…

  12. Primers determine the sensitivity of PCR-mediated hepatitis B virus DNA detection and pretreatment of PCR mixture with 8-methoxypsoralen eliminates false-positive results.

    PubMed

    Keum, W K; Park, C E; Lee, J H; Khil, L Y; Kang, I; Kim, S S; Jung, J C; Oh, S M; Woo, H J; Lee, J H; Kim, Y C; Yoon, Y; Choi, J W; Ha, J

    1997-04-30

    Most methods for the diagnosis of hepatitis B virus (HBV) infection largely depend on viral DNA detection by polymerase chain reaction (PCR) or radioimmunological assay of viral antigens or antibodies. The quality assurance program recently established in Europe reported that PCR-mediated HBV DNA detection methods used in many laboratories produced a high rate of false-positive and false-negative results. Thus, we attempted to improve the conditions of current PCR methods for detection of HBV DNA. In the present study, we applied a recently developed method of releasing HBV DNA from virion by NaOH treatment of patient serum. Using four different primer sets specific to the HBV core region, we found that the sensitivity of first-round PCR can be improved by more than two orders of magnitude depending on the primers. The second round of PCR using nested primers was sensitive enough to detect up to 10(-6) pg of the HBV DNA, which is equivalent to approximately 3 copies of the HBV genome. Among the approximately 800 HBV-infected patient sera investigated in our laboratory, more than 60% of the tested samples gave positive results in the first-round PCR. The rate of positive results obtained using our experimental conditions is very high in comparison with other reports. The reamplification of the first-round PCR reaction mixture with the nested primers produced practically 100% positive results. For diagnosis of HBV infection, we routinely used 1 microliter of patient serum, which was found to be optimum in our laboratory. Surprisingly, from 20% of our positive results, even serum diluted to 1/100 (0.01 microliter) produced a stronger signal than 1 microliter. This observation suggests that direct PCR amplification of HBV DNA released from serum by NaOH treatment has to be compensated by other DNA detection methods for correct quantitation. In order to eliminate the false positive signal resulting from the carry-over due to massive screening of a large number of

  13. 7 CFR 810.2003 - Basis of determination.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Basis of determination. Each determination of heat-damaged kernels, damaged kernels, material other than... shrunken and broken kernels. Other determinations not specifically provided for under the...

  14. Determining the Tsallis parameter via maximum entropy

    NASA Astrophysics Data System (ADS)

    Conroy, J. M.; Miller, H. G.

    2015-05-01

    The nonextensive entropic measure proposed by Tsallis [C. Tsallis, J. Stat. Phys. 52, 479 (1988), 10.1007/BF01016429] introduces a parameter, q , which is not defined but rather must be determined. The value of q is typically determined from a piece of data and then fixed over the range of interest. On the other hand, from a phenomenological viewpoint, there are instances in which q cannot be treated as a constant. We present two distinct approaches for determining q depending on the form of the equations of constraint for the particular system. In the first case the equations of constraint for the operator O ̂ can be written as Tr (FqO ̂)=C , where C may be an explicit function of the distribution function F . We show that in this case one can solve an equivalent maxent problem which yields q as a function of the corresponding Lagrange multiplier. As an illustration the exact solution of the static generalized Fokker-Planck equation (GFPE) is obtained from maxent with the Tsallis enropy. As in the case where C is a constant, if q is treated as a variable within the maxent framework the entropic measure is maximized trivially for all values of q . Therefore q must be determined from existing data. In the second case an additional equation of constraint exists which cannot be brought into the above form. In this case the additional equation of constraint may be used to determine the fixed value of q .

  15. Molecular Mechanisms of Sex Determination in Reptiles

    PubMed Central

    Rhen, T.; Schroeder, A.

    2010-01-01

    Charles Darwin first provided a lucid explanation of how gender differences evolve nearly 140 years ago. Yet, a disconnect remains between his theory of sexual selection and the mechanisms that underlie the development of males and females. In particular, comparisons between representatives of different phyla (i.e., flies and mice) reveal distinct genetic mechanisms for sexual differentiation. Such differences are hard to comprehend unless we study organisms that bridge the phylogenetic gap. Analysis of variation within monophyletic groups (i.e., amniotes) is just as important if we hope to elucidate the evolution of mechanisms underlying sexual differentiation. Here we review the molecular, cellular, morphological, and physiological changes associated with sex determination in reptiles. Most research on the molecular biology of sex determination in reptiles describes expression patterns for orthologs of mammalian sex-determining genes. Many of these genes have evolutionarily conserved expression profiles (i.e., DMRT1 and SOX9 are expressed at a higher level in developing testes vs. developing ovaries in all species), which suggests functional conservation. However, expression profiling alone does not test gene function and will not identify novel sex-determining genes or gene interactions. For that reason, we provide a prospectus on various techniques that promise to reveal new sex-determining genes and regulatory interactions among these genes. We offer specific examples of novel candidate genes and a new signaling pathway in support of these techniques. PMID:20145384

  16. Molecular mechanisms of sex determination in reptiles.

    PubMed

    Rhen, T; Schroeder, A

    2010-01-01

    Charles Darwin first provided a lucid explanation of how gender differences evolve nearly 140 years ago. Yet, a disconnect remains between his theory of sexual selection and the mechanisms that underlie the development of males and females. In particular, comparisons between representatives of different phyla (i.e., flies and mice) reveal distinct genetic mechanisms for sexual differentiation. Such differences are hard to comprehend unless we study organisms that bridge the phylogenetic gap. Analysis of variation within monophyletic groups (i.e., amniotes) is just as important if we hope to elucidate the evolution of mechanisms underlying sexual differentiation. Here we review the molecular, cellular, morphological, and physiological changes associated with sex determination in reptiles. Most research on the molecular biology of sex determination in reptiles describes expression patterns for orthologs of mammalian sex-determining genes. Many of these genes have evolutionarily conserved expression profiles (i.e., DMRT1 and SOX9 are expressed at a higher level in developing testes vs. developing ovaries in all species), which suggests functional conservation. However, expression profiling alone does not test gene function and will not identify novel sex-determining genes or gene interactions. For that reason, we provide a prospectus on various techniques that promise to reveal new sex-determining genes and regulatory interactions among these genes. We offer specific examples of novel candidate genes and a new signaling pathway in support of these techniques.

  17. Method of determining drilling fluid invasion

    SciTech Connect

    Vinegar, H. J.; Wellington, S. L.

    1985-09-10

    A method of determining the invasion of drilling fluid into a core sample taken from a borehole. A first material is added to the drilling fluid to obtain a first fluid that has an effective atomic number that is different than the effective atomic number of the connate fluids in the rock formation surrounding the borehole. A preserved core sample is collected from the borehole for scanning by a computerized axial tomographic scanner (CAT) to determine the attenuation coefficients at a plurality of points in a cross section of the core sample. The preserved core sample is scanned with a CAT at first and second energies, and the determined attenuation coefficients for the plurality of points in the cross section at each energy are used to determine an atomic number image for the cross section of the core sample. The depth of invasion of the first fluid is then determined from the atomic number image, as an indication of the depth of invasion of the drilling fluid into the core sample.

  18. [Improved methodology for quantitative determination of thiabendazole].

    PubMed

    Furusho, Noriko; Otsuki, Noriko; Ohtsuki, Takashi; Tatebe-Sasaki, Chiye; Sato, Kyoko; Akiyama, Hiroshi; Kawamura, Yoko

    2012-01-01

    The method prescribed in the 8th edition of Japan's Specifications and Standards for Food Additives (JSSFA) for the quantitative analysis of thiabendazole was improved by eliminating the use of toxic reagents such as mercuric acetate and chromium trioxide. For exclusion of mercuric acetate, a nonaqueous titration was performed using four types of solvent systems, including acetic acid:acetic anhydride (1:5), acetic acid:acetic anhydride (3:7), acetic acid alone, and formic acid:acetic acid (1:10), that did not contain mercuric compounds. Because precipitates were formed in titrations using acetic acid alone and formic acid:acetic acid (1:10), we considered that it was difficult to determine the purity using these solvent systems. However, it was confirmed that the purity of thiabendazole dissolved in the two acetic acid:acetic anhydride solvent systems can be determined using either a visual indicator or potentiometry. Specifically, the purity of thiabendazole was determined to be 99.9% (relative standard deviation (RSD) = 0.07%) for acetic acid:acetic anhydride (1:5) and 99.7% (RSD = 0.13%) for acetic acid:acetic anhydride (3:7) With respect to chromium trioxide, it was determined that chromium trioxide can be excluded using acetic acid, which conforms to the JIS K8001 standard for nonaqueous titrations. Therefore, in this study, an improved method for the quantitative determination of thiabendazole was developed without the use of toxic reagents.

  19. Psychological determinants of information searching activity.

    PubMed

    Gorunova, L

    2012-01-01

    The paper deals with the application of the activity theory in describing psychological determinants of the information searching activity. The notions of information behavior, information retrieval, information competence, information retrieval activity given in Russian and English scientific literature are compared. The research approach to the information retrieval activity based on the principles developed in the Russian theory of activity is described; and the fundamentals of G. Sukhodolsky's generalized conception of activity are presented for the first time. Analysis of empirical researches showed that specific features of information search depend on how the user evaluates information resources, information, conditions and results of search. Psychological determiners of information search may be detected as the system of evaluative alternatives, which is generated by the user during the process of his experience growth. We discovered that user's evaluation system is also related to his individual typological and personal regulative features and determines the choice of the search strategy.

  20. Method of fan sound mode structure determination

    NASA Technical Reports Server (NTRS)

    Pickett, G. F.; Sofrin, T. G.; Wells, R. W.

    1977-01-01

    A method for the determination of fan sound mode structure in the Inlet of turbofan engines using in-duct acoustic pressure measurements is presented. The method is based on the simultaneous solution of a set of equations whose unknowns are modal amplitude and phase. A computer program for the solution of the equation set was developed. An additional computer program was developed which calculates microphone locations the use of which results in an equation set that does not give rise to numerical instabilities. In addition to the development of a method for determination of coherent modal structure, experimental and analytical approaches are developed for the determination of the amplitude frequency spectrum of randomly generated sound models for use in narrow annulus ducts. Two approaches are defined: one based on the use of cross-spectral techniques and the other based on the use of an array of microphones.

  1. Epigenetic Determinism in Science and Society

    PubMed Central

    Waggoner, Miranda R.; Uller, Tobias

    2015-01-01

    The epigenetic “revolution” in science cuts across many disciplines, and it is now one of the fastest growing research areas in biology. Increasingly, claims are made that epigenetics research represents a move away from the genetic determinism that has been prominent both in biological research and in understandings of the impact of biology on society. We discuss to what extent an epigenetic framework actually supports these claims. We show that, in contrast to the received view, epigenetics research is often couched in language as deterministic as genetics research in both science and the popular press. We engage the rapidly emerging conversation about the impact of epigenetics on public discourse and scientific practice, and we contend that the notion of epigenetic determinism – or the belief that epigenetic mechanisms determine the expression of human traits and behaviors – matters for understandings of the influence of biology and society on population health. PMID:26217167

  2. Determining the sources of sounds: Psychological acoustics

    NASA Astrophysics Data System (ADS)

    Yost, William A.

    2002-05-01

    Perhaps the most important task performed by an organism's sensory system is determining objects in the world surrounding the organism. This is a challenging task for the auditory system, especially when many objects exist at the same time. The peripheral auditory system provides the neural code for the spectral-temporal structure of the complex sound impinging on the ears. It does not code for the sources of the sound. Neural centers beyond the periphery most analyze this spectral-temporal code in order to form perceptual images that make up the auditory scene. Recent psychoacoustical and perceptual research on sound source determination and segregation will be described. This research is just beginning to suggest ways in which the auditory scene is determined. [Work sponsored by NIDCD.

  3. Epigenetic Determinism in Science and Society.

    PubMed

    Waggoner, Miranda R; Uller, Tobias

    2015-04-03

    The epigenetic "revolution" in science cuts across many disciplines, and it is now one of the fastest growing research areas in biology. Increasingly, claims are made that epigenetics research represents a move away from the genetic determinism that has been prominent both in biological research and in understandings of the impact of biology on society. We discuss to what extent an epigenetic framework actually supports these claims. We show that, in contrast to the received view, epigenetics research is often couched in language as deterministic as genetics research in both science and the popular press. We engage the rapidly emerging conversation about the impact of epigenetics on public discourse and scientific practice, and we contend that the notion of epigenetic determinism - or the belief that epigenetic mechanisms determine the expression of human traits and behaviors - matters for understandings of the influence of biology and society on population health.

  4. Shape Determination for Deformed Electromagnetic Cavities

    SciTech Connect

    Akcelik, Volkan; Ko, Kwok; Lee, Lie-Quan; Li, Zhenghai; Ng, Cho-Kuen; Xiao, Liling; /SLAC

    2007-12-10

    The measured physical parameters of a superconducting cavity differ from those of the designed ideal cavity. This is due to shape deviations caused by both loose machine tolerances during fabrication and by the tuning process for the accelerating mode. We present a shape determination algorithm to solve for the unknown deviations from the ideal cavity using experimentally measured cavity data. The objective is to match the results of the deformed cavity model to experimental data through least-squares minimization. The inversion variables are unknown shape deformation parameters that describe perturbations of the ideal cavity. The constraint is the Maxwell eigenvalue problem. We solve the nonlinear optimization problem using a line-search based reduced space Gauss-Newton method where we compute shape sensitivities with a discrete adjoint approach. We present two shape determination examples, one from synthetic and the other from experimental data. The results demonstrate that the proposed algorithm is very effective in determining the deformed cavity shape.

  5. Asymptotics of Determinants of Bessel Operators

    NASA Astrophysics Data System (ADS)

    Basor, Estelle L.; Ehrhardt, Torsten

    For aL∞(+)∩L1(+) the truncated Bessel operator Bτ(a) is the integral operator acting on L2[0,τ] with the kernel where Jν stands for the Bessel function with ν>-1. In this paper we determine the asymptotics of the determinant det(I+Bτ(a)) as τ-->∞ for sufficiently smooth functions a for which a(x)≠1 for all x[0,∞). The asymptotic formula is of the form det(I+Bτ(a)) GτE with certain constants G and E, and thus similar to the well-known Szegö-Akhiezer-Kac formula for truncated Wiener-Hopf determinants.

  6. [Ethics, equity and social determinants of health].

    PubMed

    Puyol, Ángel

    2012-01-01

    The evidence shown by studies on the social determinants of health has changed the relationship between ethics and medicine. The evidence shown by studies on the social determinants of health has changed the relationship between ethics and medicine, and between a normative and a descriptive approach. Studies on the social determinants of health have also modified the traditional concept of equity, necessary health policies and the future of bioethics. More specifically: 1) the boundary between medicine and ethics has become much fuzzier, especially in the field of epidemiology, whose objectives are now inseparable from ethical considerations; 2) the concept of health equity traditionally defined as access to healthcare should be corrected or expanded to incorporate unfair health inequalities that occur before patients reach the healthcare system; and 3) the traditional autonomy bias of bioethics should be replaced by a primary concern for social justice and its relationship with health.

  7. Semi-Automatic Determination of Rockfall Trajectories

    PubMed Central

    Volkwein, Axel; Klette, Johannes

    2014-01-01

    In determining rockfall trajectories in the field, it is essential to calibrate and validate rockfall simulation software. This contribution presents an in situ device and a complementary Local Positioning System (LPS) that allow the determination of parts of the trajectory. An assembly of sensors (herein called rockfall sensor) is installed in the falling block recording the 3D accelerations and rotational velocities. The LPS automatically calculates the position of the block along the slope over time based on Wi-Fi signals emitted from the rockfall sensor. The velocity of the block over time is determined through post-processing. The setup of the rockfall sensor is presented followed by proposed calibration and validation procedures. The performance of the LPS is evaluated by means of different experiments. The results allow for a quality analysis of both the obtained field data and the usability of the rockfall sensor for future/further applications in the field. PMID:25268916

  8. Determining Yankee Nuclear Power Station neutron activation

    SciTech Connect

    Heider, K.J.; Morrissey, K.J. )

    1993-01-01

    The Yankee nuclear power station located in Rowe, Massachusetts, permanently ceased power operations on February 26, 1992, after 31 yr of operation. Yankee has since initiated decommissioning planning activities. A significant component of these activities is a determination of the extent of radiological contamination of the Yankee site. Included in this effort was determination of the extent of neutron activation of plant components. This paper describes the determination of the neutron activation of the Yankee reactor vessel, associated internals, and surrounding structures. The Yankee reactor vessel is a 600-MW(thermal) stainless steel-lined, carbon steel vessel with stainless steel internal components designed by Westinghouse. The reactor vessel is surrounded and supported by a carbon steel neutron shield tank that was filled with chromated water during plant operation. A 5-ft-thick concrete biological shield wall surrounds the neutron shield tank. A project is under way to remove the reactor vessel internals from the reactor vessel.

  9. [Diagnostic importance of HDL cholesterol determination].

    PubMed

    Reissner, J; Herrmann, W

    1990-01-01

    The present paper describes the sensitivity to quantification of changes of HDL-cholesterol in serum by two different precipitation and analytical techniques during the treatment of patients. After the precipitation of VLDL and LDL by phosphotungstic acid/magnesium chloride the chemical determination of HDL-cholesterol in serum with the Liebermann-Burchard reaction yields different results in comparison to enzymatic HDL-cholesterol determined in serum supernatant after the precipitation by polyethylene glycol 20.000. Correlation analyses of apolipoprotein A-I with enzymatic HDL-, HDL2-, HDL3-cholesterol or electrophoretic alpha-cholesterol demonstrate that the therapeutically induced changes (by training and diet) of lipid composition are more correctly reflected by the enzymatic determination of HDL-cholesterol after serum precipitation by polyethylene glycol.

  10. Determining anaerobic degradation kinetics from batch tests.

    PubMed

    Moreda, Iván López

    2016-01-01

    Data obtained from a biomethane potential (BMP) test were used in order to obtain the parameters of a kinetic model of solid wastes anaerobic degradation. The proposed model considers a hydrolysis step with a first order kinetic, a Monod kinetic for the soluble organic substrate degradation and a first order decay of microorganisms. The instantaneous release of methane was assumed. The parameters of the model are determined following a direct search optimization procedure. A 'multiple-shooting' technique was used as a first step of the optimization process. The confidence interval of the parameters was determined by using Monte Carlo simulations. Also, the distribution functions of the parameters were determined. Only the hydrolysis first order constant shows a normal distribution.

  11. Sex determination in mythology and history.

    PubMed

    Mittwoch, Ursula

    2005-02-01

    The history of ideas on how the sexes became divided spans at least three thousand years. The biblical account of the origin of Eve, and the opinions of the philosophers of classical Greece, have unexpected bearings on present-day ideas. The scientific study of sex determination can be said to have begun in the 17th century with the discovery of spermatozoa, but the origin and function of the "spermatic animalcules" eluded investigators until 1841. The mammalian egg was discovered in 1827, and in the last quarter of the century fertilization was observed. The view current at that time, that sex determination was under environmental control, gave way to the idea of chromosomal determination in the first quarter of the 20th century. The study of human and other mammalian chromosomes during the third quarter of the century, and the discovery of sex-chromosome abnormalities, emphasized the importance of the Y chromosome for male sex determination. The last quarter of the century witnessed a hunt for the "testis-determining" gene, thought to be responsible for the differentiation of Sertoli cells, and culminating in the isolation of SRY (Sry in the mouse). However, an increasing number of additional genes and growth factors were found to be required for the establishment of male sex. During the same period evidence emerged that male development was accompanied by enhanced growth, both of gonads and whole embryos. An unexpected finding was the demonstration of temperature-dependent sex determination in reptiles. With the advent of the 21st century, it was shown that Sry induces cell proliferation in fetal mouse gonads, and it has been suggested that male sex differentiation in mammals requires a higher metabolic rate. These insights could lead to a better understanding and improved treatment of abnormalities of sexual development.

  12. Shadowing Lemma and chaotic orbit determination

    NASA Astrophysics Data System (ADS)

    Spoto, Federica; Milani, Andrea

    2016-03-01

    Orbit determination is possible for a chaotic orbit of a dynamical system, given a finite set of observations, provided the initial conditions are at the central time. The Shadowing Lemma (Anosov 1967; Bowen in J Differ Equ 18:333-356, 1975) can be seen as a way to connect the orbit obtained using the observations with a real trajectory. An orbit is a shadowing of the trajectory if it stays close to the real trajectory for some amount of time. In a simple discrete model, the standard map, we tackle the problem of chaotic orbit determination when observations extend beyond the predictability horizon. If the orbit is hyperbolic, a shadowing orbit is computed by the least squares orbit determination. We test both the convergence of the orbit determination iterative procedure and the behaviour of the uncertainties as a function of the maximum number of map iterations observed. When the initial conditions belong to a chaotic orbit, the orbit determination is made impossible by numerical instability beyond a computability horizon, which can be approximately predicted by a simple formula. Moreover, the uncertainty of the results is sharply increased if a dynamical parameter is added to the initial conditions as parameter to be estimated. The Shadowing Lemma does not dictate what the asymptotic behaviour of the uncertainties should be. These phenomena have significant implications, which remain to be studied, in practical problems of orbit determination involving chaos, such as the chaotic rotation state of a celestial body and a chaotic orbit of a planet-crossing asteroid undergoing many close approaches.

  13. Polygenic Sex Determination System in Zebrafish

    PubMed Central

    Liew, Woei Chang; Bartfai, Richard; Lim, Zijie; Sreenivasan, Rajini; Siegfried, Kellee R.; Orban, Laszlo

    2012-01-01

    Background Despite the popularity of zebrafish as a research model, its sex determination (SD) mechanism is still unknown. Most cytogenetic studies failed to find dimorphic sex chromosomes and no primary sex determining switch has been identified even though the assembly of zebrafish genome sequence is near to completion and a high resolution genetic map is available. Recent publications suggest that environmental factors within the natural range have minimal impact on sex ratios of zebrafish populations. The primary aim of this study is to find out more about how sex is determined in zebrafish. Methodology/Principal Findings Using classical breeding experiments, we found that sex ratios across families were wide ranging (4.8% to 97.3% males). On the other hand, repeated single pair crossings produced broods of very similar sex ratios, indicating that parental genotypes have a role in the sex ratio of the offspring. Variation among family sex ratios was reduced after selection for breeding pairs with predominantly male or female offspring, another indication that zebrafish sex is regulated genetically. Further examinations by a PCR-based “blind assay" and array comparative genomic hybridization both failed to find universal sex-linked differences between the male and female genomes. Together with the ability to increase the sex bias of lines by selective breeding, these data suggest that zebrafish is unlikely to utilize a chromosomal sex determination (CSD) system. Conclusions/Significance Taken together, our study suggests that zebrafish sex is genetically determined with limited, secondary influences from the environment. As we have not found any sign for CSD in the species, we propose that the zebrafish has a polygenic sex determination system. PMID:22506019

  14. Measurement process error determination and control

    SciTech Connect

    Everhart, J.

    1992-01-01

    Traditional production processes have required repeated inspection activities to assure product quality. A typical production process follows this pattern: production makes product; production inspects product; Quality Control (QC) inspects product to ensure production inspected properly QC then inspects the product on a different gage to ensure the production gage performance; and QC often inspects on a different day to determine environmental effect. All of these costly inspection activities are due to the lack of confidence in the initial production measurement. The Process Measurement Assurance Program (PMAP) is a method of determining and controlling measurement error in design, development, and production. It is a preventive rather than an appraisal method that determines, improves, and controls the error in the measurement process, including measurement equipment, environment, procedure, and personnel. PMAP expands the concept of the Measurement Assurance Program developed in the 1960's by the National Bureau of Standards (NBS), today known as the National Institute of Standards and Technology (NIST). PMAP acts as a bridge in the gap between the Metrology Laboratory and the production environment by introducing standards (or certified parts) into the production process. These certified control standards are then measured as part of the production process. A control system is present to examine the measurement results of the control standards before, during, and after the manufacturing and measuring of the product. The results of the PMAP control charts determine random uncertainty and systematic (bias from the standard) error of the measurement process. The combinations of these uncertainties determine the margin of error of the measurement process. The total measurement process error is determined by combining the margin of error and the uncertainty in the control standard.

  15. Measurement process error determination and control

    SciTech Connect

    Everhart, J.

    1992-11-01

    Traditional production processes have required repeated inspection activities to assure product quality. A typical production process follows this pattern: production makes product; production inspects product; Quality Control (QC) inspects product to ensure production inspected properly QC then inspects the product on a different gage to ensure the production gage performance; and QC often inspects on a different day to determine environmental effect. All of these costly inspection activities are due to the lack of confidence in the initial production measurement. The Process Measurement Assurance Program (PMAP) is a method of determining and controlling measurement error in design, development, and production. It is a preventive rather than an appraisal method that determines, improves, and controls the error in the measurement process, including measurement equipment, environment, procedure, and personnel. PMAP expands the concept of the Measurement Assurance Program developed in the 1960`s by the National Bureau of Standards (NBS), today known as the National Institute of Standards and Technology (NIST). PMAP acts as a bridge in the gap between the Metrology Laboratory and the production environment by introducing standards (or certified parts) into the production process. These certified control standards are then measured as part of the production process. A control system is present to examine the measurement results of the control standards before, during, and after the manufacturing and measuring of the product. The results of the PMAP control charts determine random uncertainty and systematic (bias from the standard) error of the measurement process. The combinations of these uncertainties determine the margin of error of the measurement process. The total measurement process error is determined by combining the margin of error and the uncertainty in the control standard.

  16. Centriole asymmetry determines algal cell geometry

    PubMed Central

    Marshall, Wallace F.

    2012-01-01

    The mechanisms that determine the shape and organization of cells remain largely unknown. Green algae such as Chlamydomonas provide excellent model systems for studying cell geometry due to their highly reproducible cell organization. Structural and genetic studies suggest that asymmetry of the centriole (basal body) plays a critical determining role in organizing the internal organization of algal cells, through the attachment of microtubule rootlets and other large fiber systems to specific sets of microtubule triplets on the centriole. Thus to understand cell organization, it will be critical to understand how the different triplets of the centriole come to have distinct molecular identities. PMID:23026116

  17. Cutting line determination for plant propagation

    NASA Astrophysics Data System (ADS)

    Lo, Li-Yun; Hsia, Chi-Chun; Sun, Hua-Hong; Chen, Hsiang-Ju; Wu, Xin-Ting; Hu, Min-Chun

    2014-01-01

    Investigating an efficient method for plant propagation can help not only prevent extinction of plants but also facilitate the development of botanical industries. In this paper, we propose to use image processing techniques to determine the cutting-line for the propagation of two kinds of plants, i.e. Melaleuca alternifolia Cheel and Cinnamomum kanehirai Hay, which have quite different characteristics in terms of shape, structure, and propagation way (e.g. propagation by seeding and rooting, respectively). The proposed cutting line determination methods can be further applied to develop an automatic control system to reduce labor cost and increase the effectiveness of plant propagation.

  18. The Determination of Navy Family Housing Requirements

    DTIC Science & Technology

    1992-04-01

    AD-A253 487 The Determination of Navy Family Housing Requirements NA10IR1 DTIC D:~TI Eric M. Small UL E0 19925 L" Karen M. Dahut ODV fVP, gp20380...identification code (UIC), used to identify each operational unit. UICs for Navy (and Marine Corps) units are assigned by CNO; dummy UICs are assigned to non...w8226l///l//l lll/!/l/ l April 1992 The Determination of Navy Family Housing Requirements NA1OIRI Eric M. Small Karen M. Dahut Prepared pursuant to

  19. Systematic biases in radiometric diameter determinations

    NASA Technical Reports Server (NTRS)

    Spencer, John R.; Lebofsky, Larry A.; Sykes, Mark V.

    1989-01-01

    Radiometric diameter determinations are presently shown to often be significantly affected by the effect of rotation. This thermal effect of rotation depends not only on the object's thermal inertia, rotation rate, and pole orientation, but also on its temperature, since colder objects having constant rotation rate and thermal inertia will radiate less of their heat on the diurnal than on the nocturnal hemisphere. A disk-integrated beaming parameter of 0.72 is determined for the moon, and used to correct empirically for the roughness effects in thermophysical models; the standard thermal model is found to systematically underestimate cold object diameters, while overstating their albedos.

  20. Folic Acid Determination Using Electrochemical Sensors

    PubMed Central

    Mirmoghtadaie, Leila; Shamaeizadeh, Nahal; Mirzanasiri, Nooshin

    2015-01-01

    Folic acid (FA) is a water soluble vitamin that exists in many natural species. The lack of FA causes some deficiencies in the human body, so finding a simple and sensitive method for determining the FA is important. One of the modern techniques which overcome the disadvantages of conventional determination methods is the sensors. Possibility of miniaturization, the development of microfabricated electrochemical (EC) sensors has resulted in high sensitivity, portability, improved performance and spatial resolution, low power consumption, and the opportunity for integration with other technologies made Micro-Electrical-Mechanical Systems-based EC sensors suitable to identify low concentration analytes and microorganisms in a variety of mediums. PMID:26605021

  1. Folic Acid Determination Using Electrochemical Sensors.

    PubMed

    Mirmoghtadaie, Leila; Shamaeizadeh, Nahal; Mirzanasiri, Nooshin

    2015-01-01

    Folic acid (FA) is a water soluble vitamin that exists in many natural species. The lack of FA causes some deficiencies in the human body, so finding a simple and sensitive method for determining the FA is important. One of the modern techniques which overcome the disadvantages of conventional determination methods is the sensors. Possibility of miniaturization, the development of microfabricated electrochemical (EC) sensors has resulted in high sensitivity, portability, improved performance and spatial resolution, low power consumption, and the opportunity for integration with other technologies made Micro-Electrical-Mechanical Systems-based EC sensors suitable to identify low concentration analytes and microorganisms in a variety of mediums.

  2. Crop emergence date determination from spectral data

    NASA Technical Reports Server (NTRS)

    Badhwar, G. D.

    1980-01-01

    Estimating the emergence of a given crop, such as wheat or barley, is proposed using an analytic method which relies on the hypothesis that in the region (lambda = 0.70-1.35 microns) a given crop, after emergence, has a unique spectral profile in time. If the crop emerges early or late, relative to a reference standard determined for a given segment, the profile is displaced but has the same shape. Therefore, given the crop specific constants of the reference profile and a sufficient number of Landsat observations of reflectivity at specific times, the emergence date of a field can be determined.

  3. [Determination of lincomycin in the air].

    PubMed

    Churagulova, N K

    1987-03-01

    A procedure for determination of lincomycin levels in ambient air of production premises based on formation of molybdenum blue heteropoly complex was developed. The reaction requires the Folin reagent and heating in the presence of a saturated solution of sodium carbonate. The forming blue solutions are measured photometrically at 660 nm. The upper limit of lincomycin detection in the ambient air is 0.25 mg/m3. The proposed method was used in determination of the permissible concentration of the antibiotic in the ambient air of production areas. It may be used in routine sanitary supervision with respect to lincomycin levels in the ambient air of production premises.

  4. Apparatus for determining changes in limb volume

    NASA Technical Reports Server (NTRS)

    Bhagat, P. K.; Wu, V. C. (Inventor)

    1981-01-01

    Measuring apparatus for determining changes in the volume of limbs or other boty extremities by determining the cross-sectional area of such limbs many comprise a transmitter including first and second transducers for positioning on the surface of the limb at a predetermined distance there between, and a receiver including a receiver crystal for positioning on the surface of the limb. The distance between the receiver crystal and the first and second transducers are represented by respective first and second chords of the cross-section of the limb and the predetermined distance between the first and second transducers is represented by a third chord of the limb cross section.

  5. Determining enzyme kinetics via isothermal titration calorimetry.

    PubMed

    Demarse, Neil A; Killian, Marie C; Hansen, Lee D; Quinn, Colette F

    2013-01-01

    Isothermal titration calorimetry (ITC) has emerged as a powerful tool for determining the thermodynamic properties of chemical or physical equilibria such as protein-protein, ligand-receptor, and protein-DNA binding interactions. The utility of ITC for determining kinetic information, however, has not been fully recognized. Methods for collecting and analyzing data on enzyme kinetics are discussed here. The step-by-step process of converting the raw heat output rate into the kinetic parameters of the Michaelis-Menten equation is explicitly stated. The hydrolysis of sucrose by invertase is used to demonstrate the capability of the instrument and method.

  6. Methylxanthines: properties and determination in various objects

    NASA Astrophysics Data System (ADS)

    Andreeva, Elena Yu; Dmitrienko, Stanislava G.; Zolotov, Yurii A.

    2012-05-01

    Published data on the properties and determination of caffeine, theophylline, theobromine and some other methylxanthines in various objects are surveyed and described systematically. Different sample preparation procedures such as liquid extraction from solid matrices and liquid-liquid, supercritical fluid and solid-phase extraction are compared. The key methods of analysis including chromatography, electrophoresis, spectrometry and electrochemical methods are discussed. Examples of methylxanthine determination in plants, food products, energy beverages, pharmaceuticals, biological fluids and natural and waste waters are given. The bibliography includes 393 references.

  7. Determination of mercury in soil samples

    SciTech Connect

    Ayala, N.L.; Barber, T.E.; Turner, R.R.; Foust, D.F.

    1997-12-31

    A field screening method for the determination of mercury in soil samples using an iodine-based extractant was developed. The mercury compounds present in the soil samples were converted to tetraiodo mercurate (HgI{sub 4}{sup -2}), and then reduce to elemental mercury using reducing sugars. The mercury vapor present in the headspace of the sample was determined using a field portable mercury analyzer (Arizona Instruments Inc., Phoenix, Arizona). The soil samples were also analyzed using EPA method 7471, and a field method developed at Oak Ridge National Laboratory (ORNL). The results obtained using the iodine based extractant and sugar reduction compared very favorably with the other two methods employed.

  8. Determination of chlorine in silicate rocks

    USGS Publications Warehouse

    Peck, L.C.

    1959-01-01

    In a rapid accurate method for the determination of chlorine in silicate rocks, the rock powder is sintered with a sodium carbonate flux containing zinc oxide and magnesium carbonate. The sinter cake is leached with water, the resulting solution is filtered, and the filtrate is acidified with nitric acid. Chlorine is determined by titrating this solution with mercuric nitrate solution using sodium nitroprusside as the indicator. The titration is made in the dark with a beam of light shining through the solution. The end point of the titration is found by visually comparing the intensity of this beam of light with that of a similar beam of light in a reference solution.

  9. Strain Determination Using Electron Backscatter Diffraction

    SciTech Connect

    Krause, M.; Graff, A.; Altmann, F.

    2010-11-24

    In the present paper we demonstrate the use of electron backscatter diffraction (EBSD) for high resolution elastic strain determination. Here, we focus on analysis methods based on determination of small shifts in EBSD pattern with respect to a reference pattern using cross-correlation algorithms. Additionally we highlight the excellent spatial and depth resolution of EBSD and introduce the use of simulated diffraction patterns based on dynamical diffraction theory for sensitivity estimation. Moreover the potential of EBSD for strain analysis of strained thin films with particular emphasis on appropriate target preparation which respect to occurring lattice defects is demonstrated.

  10. Using Onboard Telemetry for MAVEN Orbit Determination

    NASA Technical Reports Server (NTRS)

    Lam, Try; Trawny, Nikolas; Lee, Clifford

    2013-01-01

    Determination of the spacecraft state has been traditional done using radiometric tracking data before and after the atmosphere drag pass. This paper describes our approach and results to include onboard telemetry measurements in addition to radiometric observables to refine the reconstructed trajectory estimate for the Mars Atmosphere and Volatile Evolution Mission (MAVEN). Uncertainties in the Mars atmosphere models, combined with non-continuous tracking degrade navigation accuracy, making MAVEN a key candidate for using onboard telemetry data to help complement its orbit determination process.

  11. Biomarkers coding for ovPAG-1 mRNA expression and pregnancy status in Dohne Merino ewes at an abattoir.

    PubMed

    Fayemi, Peter Olutope; Muchenje, Voster

    2013-10-01

    The objective of the present study was to determine the pregnancy status of Dohne Merino ewes at slaughter. This was done by collecting blood samples from the ewes (n = 60) during exsanguination to assay for pregnancy biomarkers using radio-immunological and TaqMan reverse transcription polymerase chain reaction techniques. The expressions of ovine pregnancy-associated glycoprotein within a range of 1.068(-09) to 8.977(-07) indicated 43.33 % ewes with pregnancy (ΔmRNA) signals at the point of slaughter. The assay validation showed that half of these ewes were truly pregnant, and most of the ewes that exhibited 'true positives' were within 56-60 kg live weight and were about 30 months old. The biomarkers used in this study, therefore, showed that approximately 22 % Dohne Merino ewes were truly pregnant at the point of slaughter.

  12. Immunological relationships of an endogenous guinea pig retrovirus with prototype mammalian type B and type D retroviruses.

    PubMed Central

    Dahlberg, J E; Tronick, S R; Aaronson, S A

    1980-01-01

    A retrovirus endogenous to guinea pig cells was earlier shown to be morphologically similar to type B and type D prototype retroviruses. Molecular hybridization techniques were used to show that guinea pig virus nucleotide sequences are endogenous to both domestic (Cavia porcellus) and indigenous (Cavia aperea) guinea pigs, but cannot be detected in the DNA of either other hystricomorph rodents or other mammals tested. Using radioimmunological techniques designed to detect interspecies relationships, the major internal polypeptide of guinea pig virus (p26) was shown to share three different sets of interspecies antigenic determinants with squirrel monkey retrovirus, viper retrovirus, and mouse mammary tumor virus. Thus, guinea pig virus appears to provide an evolutionary link between type B and D retroviruses. Images PMID:6154150

  13. Vibrational spectroscopic determination of botanical trash samples

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Cotton trash present with cotton lint can drastically affect the yarn properties and marketability of cotton. Cotton trash usually comes into contact with cotton lint from field to fabric processing operations of cotton. Conventional methods to determine cotton lint currently do not present the or...

  14. 21 CFR 26.9 - Equivalence determination.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Equivalence determination. 26.9 Section 26.9 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL MUTUAL RECOGNITION OF PHARMACEUTICAL GOOD MANUFACTURING PRACTICE REPORTS, MEDICAL DEVICE QUALITY SYSTEM AUDIT...

  15. Forensic quest for age determination of bloodstains.

    PubMed

    Bremmer, Rolf H; de Bruin, Karla G; van Gemert, Martin J C; van Leeuwen, Ton G; Aalders, Maurice C G

    2012-03-10

    Bloodstains at crime scenes are among the most important types of evidence for forensic investigators. They can be used for DNA-profiling for verifying the suspect's identity or for pattern analysis in order to reconstruct the crime. However, until now, using bloodstains to determine the time elapsed since the crime was committed is still not possible. From a criminalistic point of view, an accurate estimation of when the crime was committed enables to verify witnesses' statements, limits the number of suspects and assesses alibis. Despite several attempts and exploration of many technologies during a century, no method has been materialized into forensic practice. This review gives an overview of an extensive search in scientific literature of techniques that address the quest for age determination of bloodstains. We found that most techniques are complementary to each other, in short as well as long term age determination. Techniques are compared concerning their sensitivity for short and long term ageing of bloodstains and concerning their possible applicability to be used on a crime scene. In addition, experimental challenges like substrate variation, interdonor variation and environmental influences are addressed. Comparison of these techniques contributes to our knowledge of the physics and biochemistry in an ageing bloodstain. Further improvement and incorporation of environmental factors are necessary to enable age determination of bloodstains to be acceptable in court.

  16. Determinants of Conflict in the Philippines

    DTIC Science & Technology

    2012-06-01

    too may prompt violence.10 A. DETERMINANTS OF CONFLICT In the National Unification Commission (NUC) Report to President Fidel V. Ramos in 1993...National Unification Commission (Philippines), National Unification Commission Report to President Fidel V. Ramos on the Pursuit of a Comprehensive...12 National Unification Commission, NUC Report to PRES. FIDEL V. RAMOS on the Pursuit of a Comprehensive Peace Process (Quezon

  17. 77 FR 72385 - Honey From China; Determination

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-05

    ... COMMISSION Honey From China; Determination On the basis of the record \\1\\ developed in the subject five-year... honey from China would be likely to lead to continuation or recurrence of material injury to an industry... contained in USITC Publication 4364 (November 2012), entitled Honey from China: Investigation No....

  18. 28 CFR 36.604 - Preliminary determination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Preliminary determination. 36.604 Section 36.604 Judicial Administration DEPARTMENT OF JUSTICE NONDISCRIMINATION ON THE BASIS OF DISABILITY BY PUBLIC ACCOMMODATIONS AND IN COMMERCIAL FACILITIES Certification of State Laws or Local Building...

  19. Determination of high-risk cargo

    NASA Astrophysics Data System (ADS)

    Morris, Leo A.; Smith, Douglas E.; Khan, Siraj M.

    1994-10-01

    The approach and methodology used in the determination of the type of cargo containing concealments of commercial quantities of narcotics such as cocaine and heroin is described. This high-risk cargo enters the United States through border crossings at land, seaports and airports. The volume and variety of cargos make it a complex and challenging task for the U.S. Customs Service.

  20. Determining Consumer Preference for Furniture Product Characteristics

    ERIC Educational Resources Information Center

    Turner, Carolyn S.; Edwards, Kay P.

    1974-01-01

    The paper describes instruments for determining preferences of consumers for selected product characteristics associated with furniture choices--specifically style, color, color scheme, texture, and materials--and the procedures for administration of those instruments. Results are based on a random sampling of public housing residents. (Author/MW)

  1. 45 CFR 150.217 - Preliminary determination.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS CMS ENFORCEMENT IN GROUP AND INDIVIDUAL INSURANCE MARKETS CMS Enforcement Processes for Determining Whether States... the end of the 30-day period (and any extension), the State has not established to CMS's...

  2. 45 CFR 150.217 - Preliminary determination.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS CMS ENFORCEMENT IN GROUP AND INDIVIDUAL INSURANCE MARKETS CMS Enforcement Processes for Determining Whether States... the end of the 30-day period (and any extension), the State has not established to CMS's...

  3. 45 CFR 150.219 - Final determination.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS CMS ENFORCEMENT IN GROUP AND INDIVIDUAL INSURANCE MARKETS CMS Enforcement Processes for Determining Whether States... substantially enforce, CMS finds that the failure to substantially enforce has not been corrected, it will...

  4. 45 CFR 150.217 - Preliminary determination.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS CMS ENFORCEMENT IN GROUP AND INDIVIDUAL INSURANCE MARKETS CMS Enforcement Processes for Determining Whether States... the end of the 30-day period (and any extension), the State has not established to CMS's...

  5. 45 CFR 150.217 - Preliminary determination.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Public Welfare Department of Health and Human Services REQUIREMENTS RELATING TO HEALTH CARE ACCESS CMS ENFORCEMENT IN GROUP AND INDIVIDUAL INSURANCE MARKETS CMS Enforcement Processes for Determining Whether States... the end of the 30-day period (and any extension), the State has not established to CMS's...

  6. 45 CFR 150.219 - Final determination.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Public Welfare Department of Health and Human Services REQUIREMENTS RELATING TO HEALTH CARE ACCESS CMS ENFORCEMENT IN GROUP AND INDIVIDUAL INSURANCE MARKETS CMS Enforcement Processes for Determining Whether States... substantially enforce, CMS finds that the failure to substantially enforce has not been corrected, it will...

  7. 45 CFR 150.217 - Preliminary determination.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS CMS ENFORCEMENT IN GROUP AND INDIVIDUAL INSURANCE MARKETS CMS Enforcement Processes for Determining Whether States... the end of the 30-day period (and any extension), the State has not established to CMS's...

  8. 45 CFR 150.219 - Final determination.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS CMS ENFORCEMENT IN GROUP AND INDIVIDUAL INSURANCE MARKETS CMS Enforcement Processes for Determining Whether States... substantially enforce, CMS finds that the failure to substantially enforce has not been corrected, it will...

  9. 45 CFR 150.219 - Final determination.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS CMS ENFORCEMENT IN GROUP AND INDIVIDUAL INSURANCE MARKETS CMS Enforcement Processes for Determining Whether States... substantially enforce, CMS finds that the failure to substantially enforce has not been corrected, it will...

  10. Determinants of Happiness in Undergraduate University Students

    ERIC Educational Resources Information Center

    Flynn, Deborah M.; MacLeod, Stephanie

    2015-01-01

    This study explored the relationship between happiness, and six other life domains: Academic Success, Financial Security, Familial Support, Living Environment, Self-Image and Social Relations. Participants were one hundred and ninety- two students from a small undergraduate university. The purpose of the study was to determine which life domain…

  11. Brassinosteroid control of sex determination in maize.

    PubMed

    Hartwig, Thomas; Chuck, George S; Fujioka, Shozo; Klempien, Antje; Weizbauer, Renate; Potluri, Devi Prasad V; Choe, Sunghwa; Johal, Gurmukh S; Schulz, Burkhard

    2011-12-06

    Brassinosteroids (BRs) are plant hormones that regulate growth and development. They share structural similarities with animal steroids, which are decisive factors of sex determination. BRs are known to regulate morphogenesis and environmental stress responses, but their involvement in sex determination in plants has been only speculative. We show that BRs control sex determination in maize revealed through characterization of the classical dwarf mutant nana plant1 (na1), which also feminizes male flowers. na1 plants carry a loss-of-function mutation in a DET2 homolog--a gene in the BR biosynthetic pathway. The mutant accumulates the DET2-specific substrate (24R)-24-methylcholest-4-en-3-one with a concomitant decrease of downstream BR metabolites. Treatment of wild-type maize plants with BR biosynthesis inhibitors completely mimicked both dwarf and tasselseed phenotypes of na1 mutants. Tissue-specific na1 expression in anthers throughout their development supports the hypothesis that BRs promote masculinity of the male inflorescence. These findings suggest that, in the monoecious plant maize, BRs have been coopted to perform a sex determination function not found in plants with bisexual flowers.

  12. 32 CFR 1907.24. - Initial determination.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    .... National Defense Other Regulations Relating to National Defense CENTRAL INTELLIGENCE AGENCY CHALLENGES TO... with this section. (b) Within 10 business days of receipt of a challenge, the Coordinator shall record... written response to a challenge within 60 business days of receipt. (d) If the C/CMCG determines that...

  13. 40 CFR 61.253 - Determining compliance.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Determining compliance. 61.253 Section 61.253 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standards for Radon...

  14. 40 CFR 61.23 - Determining compliance.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 9 2013-07-01 2013-07-01 false Determining compliance. 61.23 Section 61.23 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standards for Radon...

  15. 40 CFR 61.253 - Determining compliance.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 9 2014-07-01 2014-07-01 false Determining compliance. 61.253 Section 61.253 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standards for Radon...

  16. 40 CFR 61.23 - Determining compliance.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 8 2011-07-01 2011-07-01 false Determining compliance. 61.23 Section 61.23 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standards for Radon...

  17. 40 CFR 61.23 - Determining compliance.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Determining compliance. 61.23 Section 61.23 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standards for Radon...

  18. 40 CFR 61.253 - Determining compliance.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 9 2013-07-01 2013-07-01 false Determining compliance. 61.253 Section 61.253 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standards for Radon...

  19. 40 CFR 61.23 - Determining compliance.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 9 2012-07-01 2012-07-01 false Determining compliance. 61.23 Section 61.23 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standards for Radon...

  20. 40 CFR 61.253 - Determining compliance.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 8 2011-07-01 2011-07-01 false Determining compliance. 61.253 Section 61.253 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standards for Radon...