Using Rasch Analysis to Inform Rating Scale Development

ERIC Educational Resources Information Center

Van Zile-Tamsen, Carol

2017-01-01

The use of surveys, questionnaires, and rating scales to measure important outcomes in higher education is pervasive, but reliability and validity information is often based on problematic Classical Test Theory approaches. Rasch Analysis, based on Item Response Theory, provides a better alternative for examining the psychometric quality of rating…

Neuroimaging correlates of parent ratings of working memory in typically developing children

PubMed Central

Mahone, E. Mark; Martin, Rebecca; Kates, Wendy R.; Hay, Trisha; Horská, Alena

2009-01-01

The purpose of the present study was to investigate construct validity of parent ratings of working memory in children, using a multi-trait/multi-method design including neuroimaging, rating scales, and performance-based measures. Thirty-five typically developing children completed performance-based tests of working memory and nonexecutive function (EF) skills, received volumetric MRI, and were rated by parents on both EF-specific and broad behavior rating scales. After controlling for total cerebral volume and age, parent ratings of working memory were significantly correlated with frontal gray, but not temporal, parietal, or occipital gray, or any lobar white matter volumes. Performance-based measures of working memory were also moderately correlated with frontal lobe gray matter volume; however, non-EF parent ratings and non-EF performance-based measures were not correlated with frontal lobe volumes. Results provide preliminary support for the convergent and discriminant validity of parent ratings of working memory, and emphasize their utility in exploring brain–behavior relationships in children. Rating scales that directly examine EF skills may potentially have ecological validity, not only for “everyday” function, but also as correlates of brain volume. PMID:19128526

Assessment of the degradation efficiency of full-scale biogas plants: A comparative study of degradation indicators.

PubMed

Li, Chao; Nges, Ivo Achu; Lu, Wenjing; Wang, Haoyu

2017-11-01

Increasing popularity and applications of the anaerobic digestion (AD) process has necessitated the development and identification of tools for obtaining reliable indicators of organic matter degradation rate and hence evaluate the process efficiency especially in full-scale, commercial biogas plants. In this study, four biogas plants (A1, A2, B and C) based on different feedstock, process configuration, scale and operational performance were selected and investigated. Results showed that the biochemical methane potential (BMP) based degradation rate could be use in incisively gauging process efficiency in lieu of the traditional degradation rate indicators. The BMP degradation rates ranged from 70 to 90% wherein plants A2 and C showed the highest throughput. This study, therefore, corroborates the feasibility of using the BMP degradation rate as a practical tool for evaluating process performance in full-scale biogas processes and spots light on the microbial diversity in full-scale biogas processes. Copyright © 2017 Elsevier Ltd. All rights reserved.

Reliability and Structural Validity of The Teacher Rating Scales of Early Academic Competence

ERIC Educational Resources Information Center

Reid, Erin E.; Diperna, James C.; Missall, Kristen; Volpe, Robert J.

2014-01-01

Currently, there are few strengths-based preschool rating scales that sample a wide array of behaviors believed to be essential for early academic success. The purpose of this study was to assess the factor structure of a new measure of early academic competence for at-risk preschool populations. The Teacher Rating Scales of Early Academic…

A theoretical framework for whole-plant carbon assimilation efficiency based on metabolic scaling theory: a test case using Picea seedlings.

PubMed

Wang, Zhiqiang; Ji, Mingfei; Deng, Jianming; Milne, Richard I; Ran, Jinzhi; Zhang, Qiang; Fan, Zhexuan; Zhang, Xiaowei; Li, Jiangtao; Huang, Heng; Cheng, Dongliang; Niklas, Karl J

2015-06-01

Simultaneous and accurate measurements of whole-plant instantaneous carbon-use efficiency (ICUE) and annual total carbon-use efficiency (TCUE) are difficult to make, especially for trees. One usually estimates ICUE based on the net photosynthetic rate or the assumed proportional relationship between growth efficiency and ICUE. However, thus far, protocols for easily estimating annual TCUE remain problematic. Here, we present a theoretical framework (based on the metabolic scaling theory) to predict whole-plant annual TCUE by directly measuring instantaneous net photosynthetic and respiratory rates. This framework makes four predictions, which were evaluated empirically using seedlings of nine Picea taxa: (i) the flux rates of CO(2) and energy will scale isometrically as a function of plant size, (ii) whole-plant net and gross photosynthetic rates and the net primary productivity will scale isometrically with respect to total leaf mass, (iii) these scaling relationships will be independent of ambient temperature and humidity fluctuations (as measured within an experimental chamber) regardless of the instantaneous net photosynthetic rate or dark respiratory rate, or overall growth rate and (iv) TCUE will scale isometrically with respect to instantaneous efficiency of carbon use (i.e., the latter can be used to predict the former) across diverse species. These predictions were experimentally verified. We also found that the ranking of the nine taxa based on net photosynthetic rates differed from ranking based on either ICUE or TCUE. In addition, the absolute values of ICUE and TCUE significantly differed among the nine taxa, with both ICUE and temperature-corrected ICUE being highest for Picea abies and lowest for Picea schrenkiana. Nevertheless, the data are consistent with the predictions of our general theoretical framework, which can be used to access annual carbon-use efficiency of different species at the level of an individual plant based on simple, direct measurements. Moreover, we believe that our approach provides a way to cope with the complexities of different ecosystems, provided that sufficient measurements are taken to calibrate our approach to that of the system being studied. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Evidence Based Clinical Assessment of Child and Adolescent Social Phobia: A Critical Review of Rating Scales

ERIC Educational Resources Information Center

Tulbure, Bogdan T.; Szentagotai, Aurora; Dobrean, Anca; David, Daniel

2012-01-01

Investigating the empirical support of various assessment instruments, the evidence based assessment approach expands the scientific basis of psychotherapy. Starting from Hunsley and Mash's evaluative framework, we critically reviewed the rating scales designed to measure social anxiety or phobia in youth. Thirteen of the most researched social…

Long-Term Outcomes in Children Diagnosed with Autism Spectrum Disorders in India

ERIC Educational Resources Information Center

Mhatre, Dimpi; Bapat, Deepa; Udani, Vrajesh

2016-01-01

We investigated long-term outcomes in children with diagnosis of autism spectrum disorders based on Childhood Autism Rating Scale (CARS score). Information about outcomes such as speech, friendships and activities of daily living (ADLs) was collected through telephone-based interviews. Gilliam Autism Rating Scale-2 and Vineland Social Maturity…

Factor Analysis of the Preschool Behavioral and Emotional Rating Scale for Children in Head Start Programs

ERIC Educational Resources Information Center

Cress, Cynthia; Lambert, Matthew C.; Epstein, Michael H.

2016-01-01

Strength-based assessment of behaviors in preschool children provides evidence of emotional and behavioral skills in children, rather than focusing primarily on weaknesses identified by deficit-based assessments. The Preschool Behavioral and Emotional Rating Scales (PreBERS) is a normative assessment of emotional and behavioral strengths in…

Assessing Communication Skills of Medical Students in Objective Structured Clinical Examinations (OSCE) - A Systematic Review of Rating Scales

PubMed Central

Cömert, Musa; Zill, Jördis Maria; Christalle, Eva; Dirmaier, Jörg; Härter, Martin; Scholl, Isabelle

2016-01-01

Background Teaching and assessment of communication skills have become essential in medical education. The Objective Structured Clinical Examination (OSCE) has been found as an appropriate means to assess communication skills within medical education. Studies have demonstrated the importance of a valid assessment of medical students’ communication skills. Yet, the validity of the performance scores depends fundamentally on the quality of the rating scales used in an OSCE. Thus, this systematic review aimed at providing an overview of existing rating scales, describing their underlying definition of communication skills, determining the methodological quality of psychometric studies and the quality of psychometric properties of the identified rating scales. Methods We conducted a systematic review to identify psychometrically tested rating scales, which have been applied in OSCE settings to assess communication skills of medical students. Our search strategy comprised three databases (EMBASE, PsycINFO, and PubMed), reference tracking and consultation of experts. We included studies that reported psychometric properties of communication skills assessment rating scales used in OSCEs by examiners only. The methodological quality of included studies was assessed using the COnsensus based Standards for the selection of health status Measurement INstruments (COSMIN) checklist. The quality of psychometric properties was evaluated using the quality criteria of Terwee and colleagues. Results Data of twelve studies reporting on eight rating scales on communication skills assessment in OSCEs were included. Five of eight rating scales were explicitly developed based on a specific definition of communication skills. The methodological quality of studies was mainly poor. The psychometric quality of the eight rating scales was mainly intermediate. Discussion Our results reveal that future psychometric evaluation studies focusing on improving the methodological quality are needed in order to yield psychometrically sound results of the OSCEs assessing communication skills. This is especially important given that most OSCE rating scales are used for summative assessment, and thus have an impact on medical students’ academic success. PMID:27031506

Assessing Communication Skills of Medical Students in Objective Structured Clinical Examinations (OSCE)--A Systematic Review of Rating Scales.

PubMed

Cömert, Musa; Zill, Jördis Maria; Christalle, Eva; Dirmaier, Jörg; Härter, Martin; Scholl, Isabelle

2016-01-01

Teaching and assessment of communication skills have become essential in medical education. The Objective Structured Clinical Examination (OSCE) has been found as an appropriate means to assess communication skills within medical education. Studies have demonstrated the importance of a valid assessment of medical students' communication skills. Yet, the validity of the performance scores depends fundamentally on the quality of the rating scales used in an OSCE. Thus, this systematic review aimed at providing an overview of existing rating scales, describing their underlying definition of communication skills, determining the methodological quality of psychometric studies and the quality of psychometric properties of the identified rating scales. We conducted a systematic review to identify psychometrically tested rating scales, which have been applied in OSCE settings to assess communication skills of medical students. Our search strategy comprised three databases (EMBASE, PsycINFO, and PubMed), reference tracking and consultation of experts. We included studies that reported psychometric properties of communication skills assessment rating scales used in OSCEs by examiners only. The methodological quality of included studies was assessed using the COnsensus based Standards for the selection of health status Measurement INstruments (COSMIN) checklist. The quality of psychometric properties was evaluated using the quality criteria of Terwee and colleagues. Data of twelve studies reporting on eight rating scales on communication skills assessment in OSCEs were included. Five of eight rating scales were explicitly developed based on a specific definition of communication skills. The methodological quality of studies was mainly poor. The psychometric quality of the eight rating scales was mainly intermediate. Our results reveal that future psychometric evaluation studies focusing on improving the methodological quality are needed in order to yield psychometrically sound results of the OSCEs assessing communication skills. This is especially important given that most OSCE rating scales are used for summative assessment, and thus have an impact on medical students' academic success.

Development of a Behaviorally Anchored Rating Scale for Leadership

DTIC Science & Technology

2018-01-01

Research Product 2018-06 Development of a Behaviorally Anchored Rating Scale for Leadership Tatiana H. Toumbeva Krista L...anchored Rating Scale for Leadership 5a. CONTRACT NUMBER W5J9CQ-11-D-0004 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 62278 6...observer- based behavioral measure to help instructors more reliably and accurately evaluate the development of leadership attributes and competencies

Reliability of Untrained and Experienced Raters on FEES: Rating Overall Residue is a Simple Task.

PubMed

Pisegna, Jessica M; Borders, James C; Kaneoka, Asako; Coster, Wendy J; Leonard, Rebecca; Langmore, Susan E

2018-03-07

The purpose of this study was to investigate the reliability of residue ratings on Fiberoptic Endoscopic Evaluation of Swallowing (FEES). We also examined rating differences based on experience to determine if years of experience influenced residue ratings. A group of 44 raters watched 81 FEES videos representing a wide range of residue severities for thin liquid, applesauce, and cracker boluses. Raters were untrained on the rating scales and simply rated their overall impression of residue amount on a visual analog scale (VAS) and a five-point ordinal scale in a randomized fashion across two sessions. Intra-class correlation coefficients, kappa coefficients, and ANOVAs were used to analyze agreement and differences in ratings. Residue ratings on both the VAS and ordinal scales had acceptable inter- and intra-rater reliability. Inter-rater agreement was acceptable (ICC > 0.7) for all comparisons. Intra-rater agreement was excellent on the VAS scale (r c  = 0.9) and good on the ordinal scale (k = 0.78). There was no significant difference between expert ratings and other raters based on years of experience for cracker ratings (p = 0.2119) and applesauce ratings (p = 0.2899), but there was a significant difference between clinicians on thin liquid ratings (p = 0.0005). Without any specific training, raters demonstrated high reliability when rating the overall amount of residue on FEES. Years of experience with FEES did not influence residue ratings, suggesting that expert ratings of overall residue amount are not unique or specialized. Rating the overall amount of residue on FEES appears to be a simple visual-perceptual task for puree and cracker boluses.

Category Rating Is Based on Prototypes and Not Instances: Evidence from Feedback-Dependent Context Effects

ERIC Educational Resources Information Center

Petrov, Alexander A.

2011-01-01

Context effects in category rating on a 7-point scale are shown to reverse direction depending on feedback. Context (skewed stimulus frequencies) was manipulated between and feedback within subjects in two experiments. The diverging predictions of prototype- and exemplar-based scaling theories were tested using two representative models: ANCHOR…

Assessing the Quality of Problems in Problem-Based Learning

ERIC Educational Resources Information Center

Sockalingam, Nachamma; Rotgans, Jerome; Schmidt, Henk

2012-01-01

This study evaluated the construct validity and reliability of a newly devised 32-item problem quality rating scale intended to measure the quality of problems in problem-based learning. The rating scale measured the following five characteristics of problems: the extent to which the problem (1) leads to learning objectives, (2) is familiar, (3)…

30 CFR 560.110 - What bidding systems may BOEM use?

Code of Federal Regulations, 2014 CFR

2014-07-01

... bonus with royalty rate(s) based on formula(s) or schedule(s) during one or more periods of production...-scale formula, which relates the royalty rate to the adjusted value or volume of production, or (ii) A... include the sliding-scale formula or schedule and will specify the lowest and highest royalty rates that...

30 CFR 560.110 - What bidding systems may BOEM use?

Code of Federal Regulations, 2012 CFR

2012-07-01

... bonus with royalty rate(s) based on formula(s) or schedule(s) during one or more periods of production...-scale formula, which relates the royalty rate to the adjusted value or volume of production, or (ii) A... include the sliding-scale formula or schedule and will specify the lowest and highest royalty rates that...

30 CFR 560.110 - What bidding systems may BOEM use?

Code of Federal Regulations, 2013 CFR

2013-07-01

... bonus with royalty rate(s) based on formula(s) or schedule(s) during one or more periods of production...-scale formula, which relates the royalty rate to the adjusted value or volume of production, or (ii) A... include the sliding-scale formula or schedule and will specify the lowest and highest royalty rates that...

Stability of an Electrodeposited Nanocrystalline Ni-Based Alloy Coating in Oil and Gas Wells with the Coexistence of H₂S and CO₂.

PubMed

Sui, Yiyong; Sun, Chong; Sun, Jianbo; Pu, Baolin; Ren, Wei; Zhao, Weimin

2017-06-09

The stability of an electrodeposited nanocrystalline Ni-based alloy coating in a H₂S/CO₂ environment was investigated by electrochemical measurements, weight loss method, and surface characterization. The results showed that both the cathodic and anodic processes of the Ni-based alloy coating were simultaneously suppressed, displaying a dramatic decrease of the corrosion current density. The corrosion of the Ni-based alloy coating was controlled by H₂S corrosion and showed general corrosion morphology under the test temperatures. The corrosion products, mainly consisting of Ni₃S₂, NiS, or Ni₃S₄, had excellent stability in acid solution. The corrosion rate decreased with the rise of temperature, while the adhesive force of the corrosion scale increased. With the rise of temperature, the deposited morphology and composition of corrosion products changed, the NiS content in the corrosion scale increased, and the stability and adhesive strength of the corrosion scale improved. The corrosion scale of the Ni-based alloy coating was stable, compact, had strong adhesion, and caused low weight loss, so the corrosion rates calculated by the weight loss method cannot reveal the actual oxidation rate of the coating. As the corrosion time was prolonged, the Ni-based coating was thinned while the corrosion scale thickened. The corrosion scale was closely combined with the coating, but cannot fully prevent the corrosive reactants from reaching the substrate.

Delay induced high order locking effects in semiconductor lasers

NASA Astrophysics Data System (ADS)

Kelleher, B.; Wishon, M. J.; Locquet, A.; Goulding, D.; Tykalewicz, B.; Huyet, G.; Viktorov, E. A.

2017-11-01

Multiple time scales appear in many nonlinear dynamical systems. Semiconductor lasers, in particular, provide a fertile testing ground for multiple time scale dynamics. For solitary semiconductor lasers, the two fundamental time scales are the cavity repetition rate and the relaxation oscillation frequency which is a characteristic of the field-matter interaction in the cavity. Typically, these two time scales are of very different orders, and mutual resonances do not occur. Optical feedback endows the system with a third time scale: the external cavity repetition rate. This is typically much longer than the device cavity repetition rate and suggests the possibility of resonances with the relaxation oscillations. We show that for lasers with highly damped relaxation oscillations, such resonances can be obtained and lead to spontaneous mode-locking. Two different laser types-—a quantum dot based device and a quantum well based device—are analysed experimentally yielding qualitatively identical dynamics. A rate equation model is also employed showing an excellent agreement with the experimental results.

Delay induced high order locking effects in semiconductor lasers.

PubMed

Kelleher, B; Wishon, M J; Locquet, A; Goulding, D; Tykalewicz, B; Huyet, G; Viktorov, E A

2017-11-01

Multiple time scales appear in many nonlinear dynamical systems. Semiconductor lasers, in particular, provide a fertile testing ground for multiple time scale dynamics. For solitary semiconductor lasers, the two fundamental time scales are the cavity repetition rate and the relaxation oscillation frequency which is a characteristic of the field-matter interaction in the cavity. Typically, these two time scales are of very different orders, and mutual resonances do not occur. Optical feedback endows the system with a third time scale: the external cavity repetition rate. This is typically much longer than the device cavity repetition rate and suggests the possibility of resonances with the relaxation oscillations. We show that for lasers with highly damped relaxation oscillations, such resonances can be obtained and lead to spontaneous mode-locking. Two different laser types--a quantum dot based device and a quantum well based device-are analysed experimentally yielding qualitatively identical dynamics. A rate equation model is also employed showing an excellent agreement with the experimental results.

The value of Bayes' theorem for interpreting abnormal test scores in cognitively healthy and clinical samples.

PubMed

Gavett, Brandon E

2015-03-01

The base rates of abnormal test scores in cognitively normal samples have been a focus of recent research. The goal of the current study is to illustrate how Bayes' theorem uses these base rates--along with the same base rates in cognitively impaired samples and prevalence rates of cognitive impairment--to yield probability values that are more useful for making judgments about the absence or presence of cognitive impairment. Correlation matrices, means, and standard deviations were obtained from the Wechsler Memory Scale--4th Edition (WMS-IV) Technical and Interpretive Manual and used in Monte Carlo simulations to estimate the base rates of abnormal test scores in the standardization and special groups (mixed clinical) samples. Bayes' theorem was applied to these estimates to identify probabilities of normal cognition based on the number of abnormal test scores observed. Abnormal scores were common in the standardization sample (65.4% scoring below a scaled score of 7 on at least one subtest) and more common in the mixed clinical sample (85.6% scoring below a scaled score of 7 on at least one subtest). Probabilities varied according to the number of abnormal test scores, base rates of normal cognition, and cutoff scores. The results suggest that interpretation of base rates obtained from cognitively healthy samples must also account for data from cognitively impaired samples. Bayes' theorem can help neuropsychologists answer questions about the probability that an individual examinee is cognitively healthy based on the number of abnormal test scores observed.

Assessing and mapping spatial associations among oral cancer mortality rates, concentrations of heavy metals in soil, and land use types based on multiple scale data.

PubMed

Lin, Wei-Chih; Lin, Yu-Pin; Wang, Yung-Chieh; Chang, Tsun-Kuo; Chiang, Li-Chi

2014-02-21

In this study, a deconvolution procedure was used to create a variogram of oral cancer (OC) rates. Based on the variogram, area-to-point (ATP) Poisson kriging and p-field simulation were used to downscale and simulate, respectively, the OC rate data for Taiwan from the district scale to a 1 km × 1 km grid scale. Local cluster analysis (LCA) of OC mortality rates was then performed to identify OC mortality rate hot spots based on the downscaled and the p-field-simulated OC mortality maps. The relationship between OC mortality and land use was studied by overlapping the maps of the downscaled OC mortality, the LCA results, and the land uses. One thousand simulations were performed to quantify local and spatial uncertainties in the LCA to identify OC mortality hot spots. The scatter plots and Spearman's rank correlation yielded the relationship between OC mortality and concentrations of the seven metals in the 1 km cell grid. The correlation analysis results for the 1 km scale revealed a weak correlation between OC mortality rate and concentrations of the seven studied heavy metals in soil. Accordingly, the heavy metal concentrations in soil are not major determinants of OC mortality rates at the 1 km scale at which soils were sampled. The LCA statistical results for local indicator of spatial association (LISA) revealed that the sites with high probability of high-high (high value surrounded by high values) OC mortality at the 1 km grid scale were clustered in southern, eastern, and mid-western Taiwan. The number of such sites was also significantly higher on agricultural land and in urban regions than on land with other uses. The proposed approach can be used to downscale and evaluate uncertainty in mortality data from a coarse scale to a fine scale at which useful additional information can be obtained for assessing and managing land use and risk.

Base Rates of Social Skills Acquisition/Performance Deficits, Strengths, and Problem Behaviors: An Analysis of the Social Skills Improvement System-Rating Scales

ERIC Educational Resources Information Center

Gresham, Frank M.; Elliott, Stephen N.; Kettler, Ryan J.

2010-01-01

Base rate information is important in clinical assessment because one cannot know how unusual or typical a phenomenon is without first knowing its base rate in the population. This study empirically determined the base rates of social skills acquisition and performance deficits, social skills strengths, and problem behaviors using a nationally…

Parametric analyses of summative scores may lead to conflicting inferences when comparing groups: A simulation study.

PubMed

Khan, Asaduzzaman; Chien, Chi-Wen; Bagraith, Karl S

2015-04-01

To investigate whether using a parametric statistic in comparing groups leads to different conclusions when using summative scores from rating scales compared with using their corresponding Rasch-based measures. A Monte Carlo simulation study was designed to examine between-group differences in the change scores derived from summative scores from rating scales, and those derived from their corresponding Rasch-based measures, using 1-way analysis of variance. The degree of inconsistency between the 2 scoring approaches (i.e. summative and Rasch-based) was examined, using varying sample sizes, scale difficulties and person ability conditions. This simulation study revealed scaling artefacts that could arise from using summative scores rather than Rasch-based measures for determining the changes between groups. The group differences in the change scores were statistically significant for summative scores under all test conditions and sample size scenarios. However, none of the group differences in the change scores were significant when using the corresponding Rasch-based measures. This study raises questions about the validity of the inference on group differences of summative score changes in parametric analyses. Moreover, it provides a rationale for the use of Rasch-based measures, which can allow valid parametric analyses of rating scale data.

Conners' Teacher Rating Scale for Preschool Children: A Revised, Brief, Age-Specific Measure

ERIC Educational Resources Information Center

Purpura, David J.; Lonigan, Christopher J.

2009-01-01

The Conners' Teacher Rating Scale-Revised (CTRS-R) is one of the most commonly used measures of child behavior problems. However, the scale length and the appropriateness of some of the items on the scale may reduce the usefulness of the CTRS-R for use with preschoolers. In this study, a Graded Response Model analysis based on Item Response Theory…

Validation of an Interview-Based Rating Scale Developed in Japan for Pervasive Developmental Disorders

ERIC Educational Resources Information Center

Ito, Hiroyuki; Tani, Iori; Yukihiro, Ryoji; Adachi, Jun; Hara, Koichi; Ogasawara, Megumi; Inoue, Masahiko; Kamio, Yoko; Nakamura, Kazuhiko; Uchiyama, Tokio; Ichikawa, Hironobu; Sugiyama, Toshiro; Hagiwara, Taku; Tsujii, Masatsugu

2012-01-01

The pervasive developmental disorders (PDDs) Autism Society Japan Rating Scale (PARS), an interview-based instrument for evaluating PDDs, has been developed in Japan with the aim of providing a method that (1) can be used to evaluate PDD symptoms and related support needs and (2) is simpler and easier than the currently used "gold…

Eustachian Tube Mucosal Inflammation Scale Validation Based on Digital Video Images.

PubMed

Kivekäs, Ilkka; Pöyhönen, Leena; Aarnisalo, Antti; Rautiainen, Markus; Poe, Dennis

2015-12-01

The most common cause for Eustachian tube dilatory dysfunction is mucosal inflammation. The aim of this study was to validate a scale for Eustachian tube mucosal inflammation, based on digital video clips obtained during diagnostic rigid endoscopy. A previously described four-step scale for grading the degree of inflammation of the mucosa of the Eustachian tube lumen was used for this validation study. A tutorial for use of the scale, including static images and 10 second video clips, was presented to 26 clinicians with various levels of experience. Each clinician then reviewed 35 short digital video samples of Eustachian tubes from patients and rated the degree of inflammation. A subset of the clinicians performed a second rating of the same video clips at a subsequent time. Statistical analysis of the ratings provided inter- and intrarater reliability scores. Twenty-six clinicians with various levels of experience rated a total of 35 videos. Thirteen clinicians rated the videos twice. The overall correlation coefficient for the rating of inflammation severity was relatively good (0.74, 95% confidence interval, 0.72-0.76). The intralevel correlation coefficient for intrarater reliability was high (0.86). For those who rated videos twice, the intralevel correlation coefficient improved after the first rating (0.73, to 0.76), but improvement was not statistically significant. The inflammation scale used for Eustachian tube mucosal inflammation is reliable and this scale can be used with a high level of consistency by clinicians with various levels of experience.

Stability of an Electrodeposited Nanocrystalline Ni-Based Alloy Coating in Oil and Gas Wells with the Coexistence of H2S and CO2

PubMed Central

Sui, Yiyong; Sun, Chong; Sun, Jianbo; Pu, Baolin; Ren, Wei; Zhao, Weimin

2017-01-01

The stability of an electrodeposited nanocrystalline Ni-based alloy coating in a H2S/CO2 environment was investigated by electrochemical measurements, weight loss method, and surface characterization. The results showed that both the cathodic and anodic processes of the Ni-based alloy coating were simultaneously suppressed, displaying a dramatic decrease of the corrosion current density. The corrosion of the Ni-based alloy coating was controlled by H2S corrosion and showed general corrosion morphology under the test temperatures. The corrosion products, mainly consisting of Ni3S2, NiS, or Ni3S4, had excellent stability in acid solution. The corrosion rate decreased with the rise of temperature, while the adhesive force of the corrosion scale increased. With the rise of temperature, the deposited morphology and composition of corrosion products changed, the NiS content in the corrosion scale increased, and the stability and adhesive strength of the corrosion scale improved. The corrosion scale of the Ni-based alloy coating was stable, compact, had strong adhesion, and caused low weight loss, so the corrosion rates calculated by the weight loss method cannot reveal the actual oxidation rate of the coating. As the corrosion time was prolonged, the Ni-based coating was thinned while the corrosion scale thickened. The corrosion scale was closely combined with the coating, but cannot fully prevent the corrosive reactants from reaching the substrate. PMID:28772995

Pore-scale simulation of microbial growth using a genome-scale metabolic model: Implications for Darcy-scale reactive transport

NASA Astrophysics Data System (ADS)

Tartakovsky, G. D.; Tartakovsky, A. M.; Scheibe, T. D.; Fang, Y.; Mahadevan, R.; Lovley, D. R.

2013-09-01

Recent advances in microbiology have enabled the quantitative simulation of microbial metabolism and growth based on genome-scale characterization of metabolic pathways and fluxes. We have incorporated a genome-scale metabolic model of the iron-reducing bacteria Geobacter sulfurreducens into a pore-scale simulation of microbial growth based on coupling of iron reduction to oxidation of a soluble electron donor (acetate). In our model, fluid flow and solute transport is governed by a combination of the Navier-Stokes and advection-diffusion-reaction equations. Microbial growth occurs only on the surface of soil grains where solid-phase mineral iron oxides are available. Mass fluxes of chemical species associated with microbial growth are described by the genome-scale microbial model, implemented using a constraint-based metabolic model, and provide the Robin-type boundary condition for the advection-diffusion equation at soil grain surfaces. Conventional models of microbially-mediated subsurface reactions use a lumped reaction model that does not consider individual microbial reaction pathways, and describe reactions rates using empirically-derived rate formulations such as the Monod-type kinetics. We have used our pore-scale model to explore the relationship between genome-scale metabolic models and Monod-type formulations, and to assess the manifestation of pore-scale variability (microenvironments) in terms of apparent Darcy-scale microbial reaction rates. The genome-scale model predicted lower biomass yield, and different stoichiometry for iron consumption, in comparison to prior Monod formulations based on energetics considerations. We were able to fit an equivalent Monod model, by modifying the reaction stoichiometry and biomass yield coefficient, that could effectively match results of the genome-scale simulation of microbial behaviors under excess nutrient conditions, but predictions of the fitted Monod model deviated from those of the genome-scale model under conditions in which one or more nutrients were limiting. The fitted Monod kinetic model was also applied at the Darcy scale; that is, to simulate average reaction processes at the scale of the entire pore-scale model domain. As we expected, even under excess nutrient conditions for which the Monod and genome-scale models predicted equal reaction rates at the pore scale, the Monod model over-predicted the rates of biomass growth and iron and acetate utilization when applied at the Darcy scale. This discrepancy is caused by an inherent assumption of perfect mixing over the Darcy-scale domain, which is clearly violated in the pore-scale models. These results help to explain the need to modify the flux constraint parameters in order to match observations in previous applications of the genome-scale model at larger scales. These results also motivate further investigation of quantitative multi-scale relationships between fundamental behavior at the pore scale (where genome-scale models are appropriately applied) and observed behavior at larger scales (where predictions of reactive transport phenomena are needed).

Pore-scale simulation of microbial growth using a genome-scale metabolic model: Implications for Darcy-scale reactive transport

NASA Astrophysics Data System (ADS)

Scheibe, T. D.; Tartakovsky, G.; Tartakovsky, A. M.; Fang, Y.; Mahadevan, R.; Lovley, D. R.

2012-12-01

Recent advances in microbiology have enabled the quantitative simulation of microbial metabolism and growth based on genome-scale characterization of metabolic pathways and fluxes. We have incorporated a genome-scale metabolic model of the iron-reducing bacteria Geobacter sulfurreducens into a pore-scale simulation of microbial growth based on coupling of iron reduction to oxidation of a soluble electron donor (acetate). In our model, fluid flow and solute transport is governed by a combination of the Navier-Stokes and advection-diffusion-reaction equations. Microbial growth occurs only on the surface of soil grains where solid-phase mineral iron oxides are available. Mass fluxes of chemical species associated with microbial growth are described by the genome-scale microbial model, implemented using a constraint-based metabolic model, and provide the Robin-type boundary condition for the advection-diffusion equation at soil grain surfaces. Conventional models of microbially-mediated subsurface reactions use a lumped reaction model that does not consider individual microbial reaction pathways, and describe reactions rates using empirically-derived rate formulations such as the Monod-type kinetics. We have used our pore-scale model to explore the relationship between genome-scale metabolic models and Monod-type formulations, and to assess the manifestation of pore-scale variability (microenvironments) in terms of apparent Darcy-scale microbial reaction rates. The genome-scale model predicted lower biomass yield, and different stoichiometry for iron consumption, in comparison to prior Monod formulations based on energetics considerations. We were able to fit an equivalent Monod model, by modifying the reaction stoichiometry and biomass yield coefficient, that could effectively match results of the genome-scale simulation of microbial behaviors under excess nutrient conditions, but predictions of the fitted Monod model deviated from those of the genome-scale model under conditions in which one or more nutrients were limiting. The fitted Monod kinetic model was also applied at the Darcy scale; that is, to simulate average reaction processes at the scale of the entire pore-scale model domain. As we expected, even under excess nutrient conditions for which the Monod and genome-scale models predicted equal reaction rates at the pore scale, the Monod model over-predicted the rates of biomass growth and iron and acetate utilization when applied at the Darcy scale. This discrepancy is caused by an inherent assumption of perfect mixing over the Darcy-scale domain, which is clearly violated in the pore-scale models. These results help to explain the need to modify the flux constraint parameters in order to match observations in previous applications of the genome-scale model at larger scales. These results also motivate further investigation of quantitative multi-scale relationships between fundamental behavior at the pore scale (where genome-scale models are appropriately applied) and observed behavior at larger scales (where predictions of reactive transport phenomena are needed).

Pore-scale simulation of microbial growth using a genome-scale metabolic model: Implications for Darcy-scale reactive transport

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tartakovsky, Guzel D.; Tartakovsky, Alexandre M.; Scheibe, Timothy D.

2013-09-07

Recent advances in microbiology have enabled the quantitative simulation of microbial metabolism and growth based on genome-scale characterization of metabolic pathways and fluxes. We have incorporated a genome-scale metabolic model of the iron-reducing bacteria Geobacter sulfurreducens into a pore-scale simulation of microbial growth based on coupling of iron reduction to oxidation of a soluble electron donor (acetate). In our model, fluid flow and solute transport is governed by a combination of the Navier-Stokes and advection-diffusion-reaction equations. Microbial growth occurs only on the surface of soil grains where solid-phase mineral iron oxides are available. Mass fluxes of chemical species associated withmore » microbial growth are described by the genome-scale microbial model, implemented using a constraint-based metabolic model, and provide the Robin-type boundary condition for the advection-diffusion equation at soil grain surfaces. Conventional models of microbially-mediated subsurface reactions use a lumped reaction model that does not consider individual microbial reaction pathways, and describe reactions rates using empirically-derived rate formulations such as the Monod-type kinetics. We have used our pore-scale model to explore the relationship between genome-scale metabolic models and Monod-type formulations, and to assess the manifestation of pore-scale variability (microenvironments) in terms of apparent Darcy-scale microbial reaction rates. The genome-scale model predicted lower biomass yield, and different stoichiometry for iron consumption, in comparisonto prior Monod formulations based on energetics considerations. We were able to fit an equivalent Monod model, by modifying the reaction stoichiometry and biomass yield coefficient, that could effectively match results of the genome-scale simulation of microbial behaviors under excess nutrient conditions, but predictions of the fitted Monod model deviated from those of the genome-scale model under conditions in which one or more nutrients were limiting. The fitted Monod kinetic model was also applied at the Darcy scale; that is, to simulate average reaction processes at the scale of the entire pore-scale model domain. As we expected, even under excess nutrient conditions for which the Monod and genome-scale models predicted equal reaction rates at the pore scale, the Monod model over-predicted the rates of biomass growth and iron and acetate utilization when applied at the Darcy scale. This discrepancy is caused by an inherent assumption of perfect mixing over the Darcy-scale domain, which is clearly violated in the pore-scale models. These results help to explain the need to modify the flux constraint parameters in order to match observations in previous applications of the genome-scale model at larger scales. These results also motivate further investigation of quantitative multi-scale relationships between fundamental behavior at the pore scale (where genome-scale models are appropriately applied) and observed behavior at larger scales (where predictions of reactive transport phenomena are needed).« less

Teaching program for the Unified Dyskinesia Rating Scale.

PubMed

Goetz, Christopher G; Nutt, John G; Stebbins, Glenn T; Chmura, Teresa A

2009-07-15

The Unified Dyskinesia Rating Scale (UDysRS) has been introduced as a comprehensive rating tool for the evaluation of dyskinesias in Parkinson's disease (PD). To enhance a uniform application, we developed a DVD-based training program with instructions, patient examples, and a certification exercise. For training on the objective assessment of dyskinesia, seventy PD patients spanning the gamut of dyskinesias (none to severe) were videotaped during four tasks of daily living (speaking, drinking from a cup, putting on a coat, and walking). Dyskinesia severity in seven body parts was rated by 20 international movement disorder specialists using the UDysRS for impairment. Each task was also rated for disability. Inter-rater reliability was assessed with generalized weighted kappa and intraclass correlation coefficients. For the teaching program, examples of each severity level and each body part were selected based on the criterion that they received a uniform rating (+/- 1 point) by at least 75% of the raters. For the certification exercise, four cases were selected to represent the four quartiles of overall objective UDysRS scores to reflect slight, mild, moderate, and severe dyskinesia. Each selection was based on the highest inter-rater reliability score for that quartile (minimum kappa or intraclass correlation coefficient = 0.6). UDysRS ranges for certification were calculated based on the 95% confidence interval. The teaching program lasts 41 min, and the certification exercise requires 10 min (total 51 min). This training program, based on visual examples of dyskinesia and anchored in scores generated by movement disorder experts is aimed at increasing homogeneity of ratings among and within raters and centers. Large-scale multicenter randomized clinical trials of dyskinesia treatment are strengthened by a uniform standard of scale application. 2009 Movement Disorder Society.

Criterion Noise in Ratings-Based Recognition: Evidence from the Effects of Response Scale Length on Recognition Accuracy

ERIC Educational Resources Information Center

Benjamin, Aaron S.; Tullis, Jonathan G.; Lee, Ji Hae

2013-01-01

Rating scales are a standard measurement tool in psychological research. However, research has suggested that the cognitive burden involved in maintaining the criteria used to parcel subjective evidence into ratings introduces "decision noise" and affects estimates of performance in the underlying task. There has been debate over whether…

Chemistry Resolved Kinetic Flow Modeling of TATB Based Explosives

NASA Astrophysics Data System (ADS)

Vitello, Peter; Fried, Lawrence; Howard, Mike; Levesque, George; Souers, Clark

2011-06-01

Detonation waves in insensitive, TATB based explosives are believed to have multi-time scale regimes. The initial burn rate of such explosives has a sub-microsecond time scale. However, significant late-time slow release in energy is believed to occur due to diffusion limited growth of carbon. In the intermediate time scale concentrations of product species likely change from being in equilibrium to being kinetic rate controlled. We use the thermo-chemical code CHEETAH linked to ALE hydrodynamics codes to model detonations. We term our model chemistry resolved kinetic flow as CHEETAH tracks the time dependent concentrations of individual species in the detonation wave and calculate EOS values based on the concentrations. A validation suite of model simulations compared to recent high fidelity metal push experiments at ambient and cold temperatures has been developed. We present here a study of multi-time scale kinetic rate effects for these experiments. Prepared by LLNL under Contract DE-AC52-07NA27344.

Chemistry resolved kinetic flow modeling of TATB based explosives

NASA Astrophysics Data System (ADS)

Vitello, Peter; Fried, Laurence E.; William, Howard; Levesque, George; Souers, P. Clark

2012-03-01

Detonation waves in insensitive, TATB-based explosives are believed to have multiple time scale regimes. The initial burn rate of such explosives has a sub-microsecond time scale. However, significant late-time slow release in energy is believed to occur due to diffusion limited growth of carbon. In the intermediate time scale concentrations of product species likely change from being in equilibrium to being kinetic rate controlled. We use the thermo-chemical code CHEETAH linked to an ALE hydrodynamics code to model detonations. We term our model chemistry resolved kinetic flow, since CHEETAH tracks the time dependent concentrations of individual species in the detonation wave and calculates EOS values based on the concentrations. We present here two variants of our new rate model and comparison with hot, ambient, and cold experimental data for PBX 9502.

Microelectromechanical System (MEMS) Gyroscope Noise Analysis and Scale Factor Characterization over Temperature Variation

DTIC Science & Technology

2016-07-01

bias and scale factor tests. By testing state-of-the-art gyroscopes, the effect of input rate stability and accuracy may be examined. Based on the...tumble test or bias analysis at a tilted position to remove the effect of Earth’s rotation in the scale factor test • A rate table with better rate...format guide and test procedure for coriolis vibratory gyros. Piscataway (NJ): IEEE; 2004 Dec. 3. Maio A, Smith G, Knight R, Nothwang W, Conroy J

Connecting Soil Water to Groundwater to Streams: Understanding Controls of Nitrate Losses from a Dryland Agricultural Landscape in the Upper Missouri River Watershed

NASA Astrophysics Data System (ADS)

Sigler, W. A.; Ewing, S. A.; Payn, R. A.; Jones, C. A.; Brookshire, J.; Klassen, J. K.; Jackson-Smith, D.; Weissmann, G. S.

2016-12-01

Shallow aquifers impaired by nitrate from agriculture are widespread and remediation or prevention of this problem requires understanding of N leaching rates at a variety of spatial scales. Characterization of the drivers of nitrate leaching at an intermediate scale (103 to 105 ha) is needed to bridge from field scale observations to the landscape-scale context, allowing informed water resource management decisions. Here we explore patterns in nitrate leaching rates across a depositional landform with a predominant land use of non-irrigated small grain production in the Northern Great Plains within the Upper Missouri Basin. The shallow Moccasin terrace (260,000 ha) aquifer is bounded in vertical extent by underlying shale and is isolated from mountain front stream recharge, such that aquifer recharge is dominated by infiltration of precipitation through agricultural soils. We leverage this simplified landform scale water balance to estimate leaching rates using groundwater nitrate concentrations and surface water discharge, and quantify uncertainty using a Monte Carlo approach based on spatial variation in groundwater nitrate concentrations. Landform-scale nitrate-N leaching rates ranged between 10 and 24 kg ha-1 yr-1 during 2012-2014 across two terrace catchments. These rates represent 11 to 27% of fertilizer application rates but are likely derived from a combination of soil organic N mineralization and direct fertilizer loss. While groundwater apparent age is relatively young (0-5 y) based on tritium-helium analysis, whole-aquifer turnover time calculations are an order of magnitude longer (20-23 y), suggesting aquifer heterogeneity and thus a longer potential response time to management changes than suggested by tracer-based aging. We collaborated with local producers to undertake this work, and discussed our results with community members throughout the study. Based on a follow-up survey, producers are now more likely to consider nitrate leaching when making management decisions, suggesting that location-specific producer engagement can facilitate practical solutions to non-point source water quality issues.

An improved KCF tracking algorithm based on multi-feature and multi-scale

NASA Astrophysics Data System (ADS)

Wu, Wei; Wang, Ding; Luo, Xin; Su, Yang; Tian, Weiye

2018-02-01

The purpose of visual tracking is to associate the target object in a continuous video frame. In recent years, the method based on the kernel correlation filter has become the research hotspot. However, the algorithm still has some problems such as video capture equipment fast jitter, tracking scale transformation. In order to improve the ability of scale transformation and feature description, this paper has carried an innovative algorithm based on the multi feature fusion and multi-scale transform. The experimental results show that our method solves the problem that the target model update when is blocked or its scale transforms. The accuracy of the evaluation (OPE) is 77.0%, 75.4% and the success rate is 69.7%, 66.4% on the VOT and OTB datasets. Compared with the optimal one of the existing target-based tracking algorithms, the accuracy of the algorithm is improved by 6.7% and 6.3% respectively. The success rates are improved by 13.7% and 14.2% respectively.

Rating scale for the assessment of competence in ultrasound-guided peripheral vascular access - a Delphi Consensus Study.

PubMed

Primdahl, Stine C; Todsen, Tobias; Clemmesen, Louise; Knudsen, Lars; Weile, Jesper

2016-09-21

Peripheral vascular access is vital for treatment and diagnostics of hospitalized patients. Ultrasound-guided vascular access (UGVA) is superior to the landmark technique. To ensure competence-based education, an assessment tool of UGVA competence is needed. We aimed to develop a global rating scale (RS) for assessment of UGVA competence based on opinions on the content from ultrasound experts in a modified Delphi consensus study. We included experts from anesthesiology, emergency medicine and radiology across university hospitals in Denmark. Nine elements were drafted based on existing literature and recommendations from international societies. In a multi-round survey, the experts rated the elements on a five-point Likert scale according to importance, and suggested missing elements. The final Delphi round occurred when >80% of the experts rated all elements ≥4 on the Likert scale. Sixteen experts consented to participate in the study, one withdrew consent prior to the first Delphi round, and 14 completed all three Delphi rounds. In the first Delphi round the experts excluded one element from the scale and changed the content of two elements. In the second Delphi round, the experts excluded one element from the scale. In the third Delphi round, consensus was obtained on the eight elements: preparation of utensils, ergonomics, preparation of the ultrasound device, identification of blood vessels, anatomy, hygiene, coordination of the needle, and completion of the procedure. We developed an RS for assessment of UGVA competence based on opinions of ultrasound experts through a modified Delphi consensus study.

Examining related influential factors for dental calculus scaling utilization among people with disabilities in Taiwan, a nationwide population-based study.

PubMed

Lai, Hsien-Tang; Kung, Pei-Tseng; Su, Hsun-Pi; Tsai, Wen-Chen

2014-09-01

Limited studies with large samples have been conducted on the utilization of dental calculus scaling among people with physical or mental disabilities. This study aimed to investigate the utilization of dental calculus scaling among the national disabled population. This study analyzed the utilization of dental calculus scaling among the disabled people, using the nationwide data between 2006 and 2008. Descriptive analysis and logistic regression were performed to analyze related influential factors for dental calculus scaling utilization. The dental calculus scaling utilization rate among people with physical or mental disabilities was 16.39%, and the annual utilization frequency was 0.2 times. Utilization rate was higher among the female and non-aboriginal samples. Utilization rate decreased with increased age and disability severity while utilization rate increased with income, education level, urbanization of residential area and number of chronic illnesses. Related influential factors for dental calculus scaling utilization rate were gender, age, ethnicity (aboriginal or non-aboriginal), education level, urbanization of residence area, income, catastrophic illnesses, chronic illnesses, disability types, and disability severity significantly influenced the dental calculus scaling utilization rate. Copyright © 2014 Elsevier Ltd. All rights reserved.

Effects of Smart-Tablet-Based Neurofeedback Training on Cognitive Function in Children with Attention Problems.

PubMed

Shin, Min-Sup; Jeon, Hyejin; Kim, Miyoung; Hwang, Taeho; Oh, Seo Jin; Hwangbo, Minsu; Kim, Ki Joong

2016-05-01

We sought to determine whether smart-tablet-based neurofeedback could improve executive function-including attention, working memory, and self-regulation-in children with attention problems. Forty children (10-12 years old) with attention problems, as determined by ratings on the Conners Parent Rating Scale, were assigned to either a neurofeedback group that received 16 sessions or a control group. A comprehensive test battery that assessed general intelligence, visual and auditory attention, attentional shifting, response inhibition and behavior rating scales were administered to both groups before neurofeedback training. Several neuropsychological tests were conducted at posttraining and follow-up assessment. Scores on several neuropsychological tests and parent behavior rating scales showed significant improvement in the training group but not in the controls. The improvements remained through the follow-up assessment. This study suggests that the smart-tablet-based neurofeedback training program might improve cognitive function in children with attention problems. © The Author(s) 2015.

Pore and Continuum Scale Study of the Effect of Subgrid Transport Heterogeneity on Redox Reaction Rates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Yuanyuan; Liu, Chongxuan; Zhang, Changyong

2015-08-01

A micromodel system with a pore structure for heterogeneous flow and transport was used to investigate the effect of subgrid transport heterogeneity on redox reaction rates. Hematite reductive dissolution by injecting a reduced form of flavin mononucleotide (FMNH2) at variable flow rates was used as an example to probe the variations of redox reaction rates in different subgrid transport domains. Experiments, pore-scale simulations, and macroscopic modeling were performed to measure and simulate in-situ hematite reduction and to evaluate the scaling behavior of the redox reaction rates from the pore to macroscopic scales. The results indicated that the measured pore-scale ratesmore » of hematite reduction were consistent with the predictions from a pore scale reactive transport model. A general trend is that hematite reduction followed reductant transport pathways, starting from the advection-dominated pores toward the interior of diffusion-dominated domains. Two types of diffusion domains were considered in the micromodel: a micropore diffusion domain, which locates inside solid grains or aggregates where reactant transport is limited by diffusion; and a macropore diffusion domain, which locates at wedged, dead-end pore spaces created by the grain-grain contacts. The rate of hematite reduction in the advection-dominated domain was faster than those in the diffusion-controlled domains, and the rate in the macropore diffusion domain was faster than that in the micropore domain. The reduction rates in the advection and macropore diffusion domains increased with increasing flow rate, but were affected by different mechanisms. The rate increase in the advection domain was controlled by the mass action effect as a faster flow supplied more reactants, and the rate increase in the macropore domain was more affected by the rate of mass exchange with the advection domain, which increased with increasing flow rate. The hematite reduction rate in the micropore domain was, however, not affected by the flow rate because molecular diffusion limits reductant supply to the micropore domain interior. Domain-based macroscopic models were evaluated to scale redox reaction rates from the pore to macroscopic scales. A single domain model, which ignores subgrid transport heterogeneity deviated significantly from the pore-scale results. Further analysis revealed that the rate expression for hematite reduction was not scalable from the pore to porous media using the single domain model. A three-domain model, which effectively considers subgrid reactive diffusion in the micropore and macropore domains, significantly improved model description. Overall this study revealed the importance of subgrid transport heterogeneity in the manifestation of redox reaction rates in porous media and in scaling reactions from the pore to porous media. The research also supported that the domain-based scaling approach can be used to directly scale redox reactions in porous media with subgrid transport heterogeneity.« less

Defining ADHD symptom persistence in adulthood: optimizing sensitivity and specificity.

PubMed

Sibley, Margaret H; Swanson, James M; Arnold, L Eugene; Hechtman, Lily T; Owens, Elizabeth B; Stehli, Annamarie; Abikoff, Howard; Hinshaw, Stephen P; Molina, Brooke S G; Mitchell, John T; Jensen, Peter S; Howard, Andrea L; Lakes, Kimberley D; Pelham, William E

2017-06-01

Longitudinal studies of children diagnosed with ADHD report widely ranging ADHD persistence rates in adulthood (5-75%). This study documents how information source (parent vs. self-report), method (rating scale vs. interview), and symptom threshold (DSM vs. norm-based) influence reported ADHD persistence rates in adulthood. Five hundred seventy-nine children were diagnosed with DSM-IV ADHD-Combined Type at baseline (ages 7.0-9.9 years) 289 classmates served as a local normative comparison group (LNCG), 476 and 241 of whom respectively were evaluated in adulthood (Mean Age = 24.7). Parent and self-reports of symptoms and impairment on rating scales and structured interviews were used to investigate ADHD persistence in adulthood. Persistence rates were higher when using parent rather than self-reports, structured interviews rather than rating scales (for self-report but not parent report), and a norm-based (NB) threshold of 4 symptoms rather than DSM criteria. Receiver-Operating Characteristics (ROC) analyses revealed that sensitivity and specificity were optimized by combining parent and self-reports on a rating scale and applying a NB threshold. The interview format optimizes young adult self-reporting when parent reports are not available. However, the combination of parent and self-reports from rating scales, using an 'or' rule and a NB threshold optimized the balance between sensitivity and specificity. With this definition, 60% of the ADHD group demonstrated symptom persistence and 41% met both symptom and impairment criteria in adulthood. © 2016 Association for Child and Adolescent Mental Health.

A watershed scale spatially-distributed model for streambank erosion rate driven by channel curvature

NASA Astrophysics Data System (ADS)

McMillan, Mitchell; Hu, Zhiyong

2017-10-01

Streambank erosion is a major source of fluvial sediment, but few large-scale, spatially distributed models exist to quantify streambank erosion rates. We introduce a spatially distributed model for streambank erosion applicable to sinuous, single-thread channels. We argue that such a model can adequately characterize streambank erosion rates, measured at the outsides of bends over a 2-year time period, throughout a large region. The model is based on the widely-used excess-velocity equation and comprised three components: a physics-based hydrodynamic model, a large-scale 1-dimensional model of average monthly discharge, and an empirical bank erodibility parameterization. The hydrodynamic submodel requires inputs of channel centerline, slope, width, depth, friction factor, and a scour factor A; the large-scale watershed submodel utilizes watershed-averaged monthly outputs of the Noah-2.8 land surface model; bank erodibility is based on tree cover and bank height as proxies for root density. The model was calibrated with erosion rates measured in sand-bed streams throughout the northern Gulf of Mexico coastal plain. The calibrated model outperforms a purely empirical model, as well as a model based only on excess velocity, illustrating the utility of combining a physics-based hydrodynamic model with an empirical bank erodibility relationship. The model could be improved by incorporating spatial variability in channel roughness and the hydrodynamic scour factor, which are here assumed constant. A reach-scale application of the model is illustrated on ∼1 km of a medium-sized, mixed forest-pasture stream, where the model identifies streambank erosion hotspots on forested and non-forested bends.

The Evaluation of Child Care Centers and the "Infant/Toddler Environment Rating Scale": An Environmental Critique.

ERIC Educational Resources Information Center

Moore, Gary T.

This paper questions the physical environmental adequacy of the Infant/Toddler Environment Rating Scale (ITERS) developed by Thelma Harms, Debby Cryer, and Richard Clifford at the University of North Carolina, Chapel Hill. ITERS is a 35-item scale designed to assess the quality of center-based infant and toddler care, and one of a family of child…

Entropy information of heart rate variability and its power spectrum during day and night

NASA Astrophysics Data System (ADS)

Jin, Li; Jun, Wang

2013-07-01

Physiologic systems generate complex fluctuations in their output signals that reflect the underlying dynamics. We employed the base-scale entropy method and the power spectral analysis to study the 24 hours heart rate variability (HRV) signals. The results show that such profound circadian-, age- and pathologic-dependent changes are accompanied by changes in base-scale entropy and power spectral distribution. Moreover, the base-scale entropy changes reflect the corresponding changes in the autonomic nerve outflow. With the suppression of the vagal tone and dominance of the sympathetic tone in congestive heart failure (CHF) subjects, there is more variability in the date fluctuation mode. So the higher base-scale entropy belongs to CHF subjects. With the decrease of the sympathetic tone and the respiratory frequency (RSA) becoming more pronounced with slower breathing during sleeping, the base-scale entropy drops in CHF subjects. The HRV series of the two healthy groups have the same diurnal/nocturnal trend as the CHF series. The fluctuation dynamics trend of data in the three groups can be described as “HF effect”.

Chemistry Resolved Kinetic Flow Modeling of TATB Based Explosives

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vitello, P A; Fried, L E; Howard, W M

2011-07-21

Detonation waves in insensitive, TATB based explosives are believed to have multi-time scale regimes. The initial burn rate of such explosives has a sub-microsecond time scale. However, significant late-time slow release in energy is believed to occur due to diffusion limited growth of carbon. In the intermediate time scale concentrations of product species likely change from being in equilibrium to being kinetic rate controlled. They use the thermo-chemical code CHEETAH linked to an ALE hydrodynamics code to model detonations. They term their model chemistry resolved kinetic flow as CHEETAH tracks the time dependent concentrations of individual species in the detonationmore » wave and calculates EOS values based on the concentrations. A HE-validation suite of model simulations compared to experiments at ambient, hot, and cold temperatures has been developed. They present here a new rate model and comparison with experimental data.« less

Evidence-based Assessment in Pediatric Psychology: Measures of Psychosocial Adjustment and Psychopathology

PubMed Central

Thill, Azure Welborn; Bachanas, Pamela; Garber, Judy; Miller, Karen Bearman; Abad, Mona; Bruno, Elizabeth Franks; Carter, Jocelyn Smith; David-Ferdon, Corinne; Jandasek, Barbara; Mennuti-Washburn, Jean E.; O’Mahar, Kerry; Zukerman, Jill

2008-01-01

Objective To provide an evidence-based review of measures of psychosocial adjustment and psychopathology, with a specific focus on their use in the field of pediatric psychology. Methods As part of a larger survey of pediatric psychologists from the Society of Pediatric Psychology e-mail listserv (American Psychological Association, APA, Division 54), 37 measures were selected for this psychometric review. Measures that qualified for the review fell into one of the following three categories: (a) internalizing or externalizing rating scales, (b) broad-band rating scales, and (c) self-related rating scales. Results Psychometric characteristics (i.e., three types of reliability, two types of validity) were strong for the majority of measures reviewed, with 34 of the 37 measures meeting “well-established” evidence-based assessment (EBA) criteria. Strengths and weaknesses of existing measures were noted. Conclusions Recommendations for future work in this area of assessment are presented, including suggestions that more fine-grained EBA criteria be developed and that evidence-based “profiles” be devised for each measure. PMID:17728305

Item-Based Psychometrics of the Preschool Behavioral and Emotional Rating Scale

ERIC Educational Resources Information Center

Cress, Cynthia J.; Lambert, Matthew C.; Epstein, Michael H.

2014-01-01

The Preschool Behavioral and Emotional Rating Scale (PreBERS) is an assessment of emotional and behavioral strengths in preschoolers with well-established reliability and validity for educational and clinical application in children with and without disabilities. The present study provides further evidence of psychometric rigor for items and…

Centre-Based Child Care Quality in Urban Australia

ERIC Educational Resources Information Center

Ishimine, Karin; Wilson, Rachel

2009-01-01

This study investigates the quality of childcare centres in urban Australian communities designated according to different bands of Centre Location Demographics (CLD). Childcare centres were assessed using the Early Childhood Environment Rating Scale- Revised Edition (ECERS-R) and the Early Childhood Environment Rating Scale-Extension (ECERS-E).…

A grid of MHD models for stellar mass loss and spin-down rates of solar analogs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cohen, O.; Drake, J. J.

2014-03-01

Stellar winds are believed to be the dominant factor in the spin-down of stars over time. However, stellar winds of solar analogs are poorly constrained due to observational challenges. In this paper, we present a grid of magnetohydrodynamic models to study and quantify the values of stellar mass loss and angular momentum loss rates as a function of the stellar rotation period, magnetic dipole component, and coronal base density. We derive simple scaling laws for the loss rates as a function of these parameters, and constrain the possible mass loss rate of stars with thermally driven winds. Despite the successmore » of our scaling law in matching the results of the model, we find a deviation between the 'solar dipole' case and a real case based on solar observations that overestimates the actual solar mass loss rate by a factor of three. This implies that the model for stellar fields might require a further investigation with additional complexity. Mass loss rates in general are largely controlled by the magnetic field strength, with the wind density varying in proportion to the confining magnetic pressure B {sup 2}. We also find that the mass loss rates obtained using our grid models drop much faster with the increase in rotation period than scaling laws derived using observed stellar activity. For main-sequence solar-like stars, our scaling law for angular momentum loss versus poloidal magnetic field strength retrieves the well-known Skumanich decline of angular velocity with time, Ω{sub *}∝t {sup –1/2}, if the large-scale poloidal magnetic field scales with rotation rate as B{sub p}∝Ω{sub ⋆}{sup 2}.« less

An Evaluation of a Diabetes Self-Management Education (DSME) Intervention Delivered Using Avatar-Based Technology: Certified Diabetes Educators' Ratings and Perceptions.

PubMed

Duncan-Carnesciali, Joanne; Wallace, Barbara C; Odlum, Michelle

2018-06-01

Purpose The purpose of this study was to evaluate the perceptions that certified diabetes educators (CDEs), of diverse health professions, have of a culturally appropriate e-health intervention that used avatar-based technology. Methods Cross-sectional, survey-based design using quantitative and qualitative paradigms. A logic model framed the study, which centered on the broad and general concepts leading to study outcomes. In total, 198 CDEs participated in the evaluation. Participants were mostly female and represented an age range of 26 to 76 years. The profession representative of the sample was registered nurses. Study setting and data collection occurred at https://www.surveymonkey.com/r/AvatarVideoSurvey-for-Certified_Diabetes_Educators . Study instruments used were the Basic Demographics Survey (BD-13), Educational Material Use and Rating of Quality Scale (EMU-ROQ-9), Marlowe-Crowne Social Desirability Survey (MS-SOC-DES-CDE-13), Quality of Avatar Video Rating Scale (QAVRS-7), Recommend Avatar to Patients Scale (RAVTPS-3), Recommend Avatar Video to Health Professionals Scale (RAVTHP-3), and Avatar Video Applications Scale (AVAPP-1). Statistical analysis used included t tests, Pearson product moment correlations, backward stepwise regression, and content/thematic analysis. Results Age, ethnicity, Arab/Middle Eastern, Asian, and white/European descents were significant predictors of a high-quality rating of the video. Thematic and content analysis of the data revealed an overall positive perception of the video. Conclusions An e-health intervention grounded in evidence-based health behavior theories has potential to increase access to diabetes self-management education as evidenced in the ratings and perceptions of the video by CDEs.

The reliability and validity of flight task workload ratings

NASA Technical Reports Server (NTRS)

Childress, M. E.; Hart, S. G.; Bortolussi, M. R.

1982-01-01

Twelve instrument-rated general aviation pilots each flew two scenarios in a motion-base simulator. During each flight, the pilots verbally estimated their workload every three minutes. Following each flight, they again estimated workload for each flight segment and also rated their overall workload, perceived performance, and 13 specific factors on a bipolar scale. The results indicate that time (a priori, inflight, or postflight) of eliciting ratings, period to be covered by the ratings (a specific moment in time or a longer period), type of rating scale, and rating method (verbal, written, or other) may be important variables. Overall workload ratings appear to be predicted by different specific scales depending upon the situation, with activity level the best predictor. Perceived performance seems to bear little relationship to observer-rated performance when pilots rate their overall performance and an observer rates specific behaviors. Perceived workload and performance also seem unrelated.

Comparison of proposed alternative methods for rescaling dialysis dose: resting energy expenditure, high metabolic rate organ mass, liver size, and body surface area.

PubMed

Daugirdas, John T; Levin, Nathan W; Kotanko, Peter; Depner, Thomas A; Kuhlmann, Martin K; Chertow, Glenn M; Rocco, Michael V

2008-01-01

A number of denominators for scaling the dose of dialysis have been proposed as alternatives to the urea distribution volume (V). These include resting energy expenditure (REE), mass of high metabolic rate organs (HMRO), visceral mass, and body surface area. Metabolic rate is an unlikely denominator as it varies enormously among humans with different levels of activity and correlates poorly with the glomerular filtration rate. Similarly, scaling based on HMRO may not be optimal, as many organs with high metabolic rates such as spleen, brain, and heart are unlikely to generate unusually large amounts of uremic toxins. Visceral mass, in particular the liver and gut, has potential merit as a denominator for scaling; liver size is related to protein intake and the liver, along with the gut, is known to be responsible for the generation of suspected uremic toxins. Surface area is time-honored as a scaling method for glomerular filtration rate and scales similarly to liver size. How currently recommended dialysis doses might be affected by these alternative rescaling methods was modeled by applying anthropometric equations to a large group of dialysis patients who participated in the HEMO study. The data suggested that rescaling to REE would not be much different from scaling to V. Scaling to HMRO mass would mandate substantially higher dialysis doses for smaller patients of either gender. Rescaling to liver mass would require substantially more dialysis for women compared with men at all levels of body size. Rescaling to body surface area would require more dialysis for smaller patients of either gender and also more dialysis for women of any size. Of these proposed alternative rescaling measures, body surface area may be the best, because it reflects gender-based scaling of liver size and thereby the rate of generation of uremic toxins.

Comparability of Mayo-Portland Adaptability Inventory ratings by staff, significant others and people with acquired brain injury.

PubMed

Malec, James F

2004-06-01

To determine the internal consistency, reliability and comparability of the Mayo-Portland Adaptability Inventory (MPAI-4) and sub-scales completed by people with acquired brain injury (ABI), family and significant others (SO) and rehabilitation staff. 134 people with ABI consecutively seen for outpatient rehabilitation evaluation. MPAI-4 protocols based on independent ratings by the people with ABI undergoing evaluation, SO and rehabilitation staff were submitted to Rasch Facets analysis to determine the internal consistency of the overall measure and sub-scales (Ability, Adjustment and Participation indices) for each rater group and for a composite measure based on all rater groups. Rater agreement for individual items was also examined. Rasch indicators of internal consistency were entirely within acceptable limits for 3-rater composite full scale and sub-scale measures; these indicators were generally within acceptable limits for measures based on a single rater group. Item agreement was generally acceptable; disagreements suggested various sources of bias for specific rater groups. The MPAI-4 possesses satisfactory internal consistency regardless of rating source. A composite measure based on ratings made independently by people with ABI, SO and staff may serve as a 'gold standard' for research purposes. In the clinical setting, assessment of varying perspectives and biases may not only best represent outcome as evaluated by all parties involved but be essential to developing effective rehabilitation plans.

Convergence and divergence in a long-term old-field succession: the importance of spatial scale and species abundance.

PubMed

Li, Shao-Peng; Cadotte, Marc W; Meiners, Scott J; Pu, Zhichao; Fukami, Tadashi; Jiang, Lin

2016-09-01

Whether plant communities in a given region converge towards a particular stable state during succession has long been debated, but rarely tested at a sufficiently long time scale. By analysing a 50-year continuous study of post-agricultural secondary succession in New Jersey, USA, we show that the extent of community convergence varies with the spatial scale and species abundance classes. At the larger field scale, abundance-based dissimilarities among communities decreased over time, indicating convergence of dominant species, whereas incidence-based dissimilarities showed little temporal tend, indicating no sign of convergence. In contrast, plots within each field diverged in both species composition and abundance. Abundance-based successional rates decreased over time, whereas rare species and herbaceous plants showed little change in temporal turnover rates. Initial abandonment conditions only influenced community structure early in succession. Overall, our findings provide strong evidence for scale and abundance dependence of stochastic and deterministic processes over old-field succession. © 2016 John Wiley & Sons Ltd/CNRS.

Evaluation of three flame retardant (FR) grey cotton blend nonwoven fabrics using micro-scale combustion calorimetry

USDA-ARS?s Scientific Manuscript database

Unbleached (grey or greige) cotton nonwoven (NW) fabrics (with 12.5% polypropylene scrim) were treated with three phosphate-nitrogen based FR formulations and evaluated with micro-scale combustion calorimetry (MCC). Heat release rate (HRR), Peak heat rate (PHRR), temperature at peak heat release ra...

An International Assessment of the Emotional and Behavioral Strengths of Youth

ERIC Educational Resources Information Center

Lappalainen, Kristiina; Savolainen, Hannu; Kuorelahti, Matti; Epstein, Michael H.

2009-01-01

The assessment of emotional and behavioral strengths has been identified as an important part of the assessment process for children referred for specialized services. The Behavioral and Emotional Rating Scale-2 (BERS-2; Epstein, Behavioral and Emotional Rating Scale: a strength-based approach to assessment. PRO-Ed, Austin, TX, 2004) was developed…

The brief negative symptom scale: validation of the German translation and convergent validity with self-rated anhedonia and observer-rated apathy.

PubMed

Bischof, Martin; Obermann, Caitriona; Hartmann, Matthias N; Hager, Oliver M; Kirschner, Matthias; Kluge, Agne; Strauss, Gregory P; Kaiser, Stefan

2016-11-22

Negative symptoms are considered core symptoms of schizophrenia. The Brief Negative Symptom Scale (BNSS) was developed to measure this symptomatic dimension according to a current consensus definition. The present study examined the psychometric properties of the German version of the BNSS. To expand former findings on convergent validity, we employed the Temporal Experience Pleasure Scale (TEPS), a hedonic self-report that distinguishes between consummatory and anticipatory pleasure. Additionally, we addressed convergent validity with observer-rated assessment of apathy with the Apathy Evaluation Scale (AES), which was completed by the patient's primary nurse. Data were collected from 75 in- and outpatients from the Psychiatric Hospital, University Zurich diagnosed with either schizophrenia or schizoaffective disorder. We assessed convergent and discriminant validity, internal consistency and inter-rater reliability. We largely replicated the findings of the original version showing good psychometric properties of the BNSS. In addition, the primary nurses evaluation correlated moderately with interview-based clinician rating. BNSS anhedonia items showed good convergent validity with the TEPS. Overall, the German BNSS shows good psychometric properties comparable to the original English version. Convergent validity extends beyond interview-based assessments of negative symptoms to self-rated anhedonia and observer-rated apathy.

Motion sickness in cats - A symptom rating scale used in laboratory and flight tests

NASA Technical Reports Server (NTRS)

Suri, K. B.; Daunton, N. G.; Crampton, G. H.

1979-01-01

The cat is proposed as a model for the study of motion and space sickness. Development of a scale for rating the motion sickness severity in the cat is described. The scale is used to evaluate an antimotion sickness drug, d-amphetamine plus scopolamine, and to determine whether it is possible to predict sickness susceptibility during parabolic flight, including zero-G maneuvers, from scores obtained during ground based trials.

Application of the Repetitions in Reserve-Based Rating of Perceived Exertion Scale for Resistance Training

PubMed Central

Cronin, John; Storey, Adam; Zourdos, Michael C.

2016-01-01

ABSTRACT RATINGS OF PERCEIVED EXERTION ARE A VALID METHOD OF ESTIMATING THE INTENSITY OF A RESISTANCE TRAINING EXERCISE OR SESSION. SCORES ARE GIVEN AFTER COMPLETION OF AN EXERCISE OR TRAINING SESSION FOR THE PURPOSES OF ATHLETE MONITORING. HOWEVER, A NEWLY DEVELOPED SCALE BASED ON HOW MANY REPETITIONS ARE REMAINING AT THE COMPLETION OF A SET MAY BE A MORE PRECISE TOOL. THIS APPROACH ADJUSTS LOADS AUTOMATICALLY TO MATCH ATHLETE CAPABILITIES ON A SET-TO-SET BASIS AND MAY MORE ACCURATELY GAUGE INTENSITY AT NEAR-LIMIT LOADS. THIS ARTICLE OUTLINES HOW TO INCORPORATE THIS NOVEL SCALE INTO A TRAINING PLAN. PMID:27531969

Methods for estimating comparable prevalence rates of food insecurity experienced by adults in 147 countries and areas

NASA Astrophysics Data System (ADS)

Nord, Mark; Cafiero, Carlo; Viviani, Sara

2016-11-01

Statistical methods based on item response theory are applied to experiential food insecurity survey data from 147 countries, areas, and territories to assess data quality and develop methods to estimate national prevalence rates of moderate and severe food insecurity at equal levels of severity across countries. Data were collected from nationally representative samples of 1,000 adults in each country. A Rasch-model-based scale was estimated for each country, and data were assessed for consistency with model assumptions. A global reference scale was calculated based on item parameters from all countries. Each country's scale was adjusted to the global standard, allowing for up to 3 of the 8 scale items to be considered unique in that country if their deviance from the global standard exceeded a set tolerance. With very few exceptions, data from all countries were sufficiently consistent with model assumptions to constitute reasonably reliable measures of food insecurity and were adjustable to the global standard with fair confidence. National prevalence rates of moderate-or-severe food insecurity assessed over a 12-month recall period ranged from 3 percent to 92 percent. The correlations of national prevalence rates with national income, health, and well-being indicators provide external validation of the food security measure.

Use of an uncertainty analysis for genome-scale models as a prediction tool for microbial growth processes in subsurface environments.

PubMed

Klier, Christine

2012-03-06

The integration of genome-scale, constraint-based models of microbial cell function into simulations of contaminant transport and fate in complex groundwater systems is a promising approach to help characterize the metabolic activities of microorganisms in natural environments. In constraint-based modeling, the specific uptake flux rates of external metabolites are usually determined by Michaelis-Menten kinetic theory. However, extensive data sets based on experimentally measured values are not always available. In this study, a genome-scale model of Pseudomonas putida was used to study the key issue of uncertainty arising from the parametrization of the influx of two growth-limiting substrates: oxygen and toluene. The results showed that simulated growth rates are highly sensitive to substrate affinity constants and that uncertainties in specific substrate uptake rates have a significant influence on the variability of simulated microbial growth. Michaelis-Menten kinetic theory does not, therefore, seem to be appropriate for descriptions of substrate uptake processes in the genome-scale model of P. putida. Microbial growth rates of P. putida in subsurface environments can only be accurately predicted if the processes of complex substrate transport and microbial uptake regulation are sufficiently understood in natural environments and if data-driven uptake flux constraints can be applied.

Discriminant of validity the Wender Utah rating scale in Iranian adults.

PubMed

Farokhzadi, Farideh; Mohammadi, Mohammad Reza; Salmanian, Maryam

2014-01-01

The aim of this study is the normalization of the Wender Utah rating scale which is used to detect adults with Attention-Deficit and Hyperactivity Disorder (ADHD). Available sampling method was used to choose 400 parents of children (200 parents of children with ADHD as compared to 200 parents of normal children). Wender Utah rating scale, which has been designed to diagnose ADHD in adults, is filled out by each of the parents to most accurately diagnose of ADHD in parents. Wender Utah rating scale was divided into 6 sub scales which consist of dysthymia, oppositional defiant disorder; school work problems, conduct disorder, anxiety, and ADHD were analyzed with exploratory factor analysis method. The value of (Kaiser-Meyer-Olkin) KMO was 86.5% for dysthymia, 86.9% for oppositional defiant disorder, 77.5% for school related problems, 90.9% for conduct disorder, 79.6% for anxiety and 93.5% for Attention deficit/hyperactivity disorder, also the chi square value based on Bartlett's Test was 2242.947 for dysthymia, 2239.112 for oppositional defiant disorder, 1221.917 for school work problems, 5031.511 for conduct, 1421.1 for anxiety, and 7644.122 for ADHD. Since mentioned values were larger than the chi square critical values (P<0.05), it found that the factor correlation matrix is appropriate for factor analysis. Based on the findings, we can conclude that Wender Utah rating scale can be appropriately used for predicting dysthymia, oppositional defiant disorder, school work problems, conduct disorder, anxiety, in adults with ADHD.

A stochastic two-scale model for pressure-driven flow between rough surfaces

PubMed Central

Larsson, Roland; Lundström, Staffan; Wall, Peter; Almqvist, Andreas

2016-01-01

Seal surface topography typically consists of global-scale geometric features as well as local-scale roughness details and homogenization-based approaches are, therefore, readily applied. These provide for resolving the global scale (large domain) with a relatively coarse mesh, while resolving the local scale (small domain) in high detail. As the total flow decreases, however, the flow pattern becomes tortuous and this requires a larger local-scale domain to obtain a converged solution. Therefore, a classical homogenization-based approach might not be feasible for simulation of very small flows. In order to study small flows, a model allowing feasibly-sized local domains, for really small flow rates, is developed. Realization was made possible by coupling the two scales with a stochastic element. Results from numerical experiments, show that the present model is in better agreement with the direct deterministic one than the conventional homogenization type of model, both quantitatively in terms of flow rate and qualitatively in reflecting the flow pattern. PMID:27436975

Objective structured assessment of nontechnical skills: Reliability of a global rating scale for the in-training assessment in the operating room.

PubMed

Dedy, Nicolas J; Szasz, Peter; Louridas, Marisa; Bonrath, Esther M; Husslein, Heinrich; Grantcharov, Teodor P

2015-06-01

Nontechnical skills are critical for patient safety in the operating room (OR). As a result, regulatory bodies for accreditation and certification have mandated the integration of these competencies into postgraduate education. A generally accepted approach to the in-training assessment of nontechnical skills, however, is lacking. The goal of the present study was to develop an evidence-based and reliable tool for the in-training assessment of residents' nontechnical performance in the OR. The Objective Structured Assessment of Nontechnical Skills tool was designed as a 5-point global rating scale with descriptive anchors for each item, based on existing evidence-based frameworks of nontechnical skills, as well as resident training requirements. The tool was piloted on scripted videos and refined in an iterative process. The final version was used to rate residents' performance in recorded OR crisis simulations and during live observations in the OR. A total of 37 simulations and 10 live procedures were rated. Interrater agreement was good for total mean scores, both in simulation and in the real OR, with intraclass correlation coefficients >0.90 in all settings for average and single measures. Internal consistency of the scale was high (Cronbach's alpha = 0.80). The Objective Structured Assessment of Nontechnical Skills global rating scale was developed as an evidence-based tool for the in-training assessment of residents' nontechnical performance in the OR. Unique descriptive anchors allow for a criterion-referenced assessment of performance. Good reliability was demonstrated in different settings, supporting applications in research and education. Copyright © 2015 Elsevier Inc. All rights reserved.

Excellent reliability of the Hamilton Depression Rating Scale (HDRS-21) in Indonesia after training.

PubMed

Istriana, Erita; Kurnia, Ade; Weijers, Annelies; Hidayat, Teddy; Pinxten, Lucas; de Jong, Cor; Schellekens, Arnt

2013-09-01

The Hamilton Depression Rating Scale (HDRS) is the most widely used depression rating scale worldwide. Reliability of HDRS has been reported mainly from Western countries. The current study tested the reliability of HDRS ratings among psychiatric residents in Indonesia, before and after HDRS training. The hypotheses were that: (i) prior to the training reliability of HDRS ratings is poor; and (ii) HDRS training can improve reliability of HDRS ratings to excellent levels. Furthermore, we explored cultural validity at item level. Videotaped HDRS interviews were rated by 30 psychiatric residents before and after 1 day of HDRS training. Based on a gold standard rating, percentage correct ratings and deviation from the standard were calculated. Correct ratings increased from 83% to 99% at item level and from 70% to 100% for the total rating. The average deviation from the gold standard rating improved from 0.07 to 0.02 at item level and from 2.97 to 0.46 for the total rating. HDRS assessment by psychiatric trainees in Indonesia without prior training is unreliable. A short, evidence-based HDRS training improves reliability to near perfect levels. The outlined training program could serve as a template for HDRS trainings. HDRS items that may be less valid for assessment of depression severity in Indonesia are discussed. Copyright © 2013 Wiley Publishing Asia Pty Ltd.

Quality Assessment of Physical and Organoleptic Instant Corn Rice on Scale-Up Process

NASA Astrophysics Data System (ADS)

Kumalasari, R.; Ekafitri, R.; Indrianti, N.

2017-12-01

Development of instant corn rice product has been successfully conducted on a laboratory scale. Corn has high carbohydrate content but low in fiber. The addition of fiber in instant corn rice, intended to improve the functioning of the product, and replace fiber loss during the process. Scale up process of Instant corn rice required to increase the production capacity. Scale up was the process to get identic output on a larger scale based on predetermined production scale. This study aimed to assess the changes and differences in the quality of instant corn rice during scale up. Instant corn rice scale up was done on production capacity 3 kg, 4 kg and 5 kg. Results showed that scale up of instant corn rice producing products with rehydration ratio ranges between 514% - 570%, the absorption rate ranged between 414% - 470%, swelling rate ranging between 119% - 134%, bulk density ranged from 0.3661 to 0.4745 (g/ml) and porosity ranging between 30-37%. The physical quality of instant corn rice on scale up were stable from the ones at laboratory scale on swelling rate, rehydration ratio, and absorption rate but not stable on bulk density and porosity. Organoleptic qualities were stable at increased scale compared on a laboratory scale. Bulk density was higher than those at laboratory scale, and the porosity was lower than those at laboratory scale.

Psychometric properties of the Multidimensional Assessment of Fatigue scale in traumatic brain injury: an NIDRR Traumatic Brain Injury Model Systems study.

PubMed

Lequerica, Anthony; Bushnik, Tamara; Wright, Jerry; Kolakowsky-Hayner, Stephanie A; Hammond, Flora M; Dijkers, Marcel P; Cantor, Joshua

2012-01-01

To investigate the psychometric properties of the Multidimensional Assessment of Fatigue (MAF) scale in a traumatic brain injury (TBI) sample. Prospective survey study. Community. One hundred sixty-seven individuals with TBI admitted for inpatient rehabilitation, enrolled into the TBI Model Systems national database, and followed up at either the first or second year postinjury. Not applicable. Multidimensional Assessment of Fatigue. The initial analysis, using items 1 to 14, which are based on a 10-point rating scale, found that only 1 item ("walking") misfit the overall construct of fatigue in this TBI population. However, this 10-point rating scale was found to have disordered thresholds. When ratings were collapsed into 4 response categories, all MAF items used to calculate the Global Fatigue Index formed a unidimensional scale. Findings generally support the unidimensionality of the MAF when used in a TBI population but call into question the use of a 10-point rating scale for items 1 to 14. Further study is needed to investigate the use of a 4-category rating scale across all items and the fit of the "walking" item for a measure of fatigue among individuals with TBI.

Real-time quantum cascade laser-based infrared microspectroscopy in-vivo

NASA Astrophysics Data System (ADS)

Kröger-Lui, N.; Haase, K.; Pucci, A.; Schönhals, A.; Petrich, W.

2016-03-01

Infrared microscopy can be performed to observe dynamic processes on a microscopic scale. Fourier-transform infrared spectroscopy-based microscopes are bound to limitations regarding time resolution, which hampers their potential for imaging fast moving systems. In this manuscript we present a quantum cascade laser-based infrared microscope which overcomes these limitations and readily achieves standard video frame rates. The capabilities of our setup are demonstrated by observing dynamical processes at their specific time scales: fermentation, slow moving Amoeba Proteus and fast moving Caenorhabditis elegans. Mid-infrared sampling rates between 30 min and 20 ms are demonstrated.

Rasch Analysis of the Malaysian Secondary School Student Leadership Inventory (M3SLI).

PubMed

Ling, Mei-Teng

The importance of instilling leadership skills in students has always been a main subject of discussion in Malaysia. Malaysian Secondary School Students Leadership Inventory (M3SLI) is an instrument which has been piloted tested in year 2013. The main purpose of this study is to examine and optimize the functioning of the rating scale categories in M3SLI by investigating the rating scale category counts, average and expected rating scale category measures, and steps calibrations. In detail, the study was aimed to (1) identify whether the five-point rating scale was functioning as intended and (2) review the effect of a rating scale category revision on the psychometric characteristics of M3SLI. The study was carried out on students aged between 13 to 18 years (2183 students) by stratified random sampling in 26 public schools in Sabah, Malaysia, with the results analysed using Winsteps. This study found that the rating scale of Personality and Values constructs needed to be modified while the scale for Leadership Skills was maintained. For future studies, other aspects of psychometric properties like differential item functioning (DIF) based on demographic variables such as gender, school locations and forms should be researched on prior to the use of the instrument.

A Scale to Assist the Diagnosis of Autism and Asperger's Disorder in Adults (RAADS): A Pilot Study

ERIC Educational Resources Information Center

Ritvo, Riva Ariella; Ritvo, Edward R.; Guthrie, Donald; Yuwiler, Arthur; Ritvo, Max Joseph; Weisbender, Leo

2008-01-01

An empirically based 78 question self-rating scale based on DSM-IV-TR and ICD-10 criteria was developed to assist clinicians' diagnosis of adults with autism and Asperger's Disorder-the Ritvo Autism and Asperger's Diagnostic Scale (RAADS). It was standardized on 17 autistic and 20 Asperger's Disorder and 57 comparison subjects. Both autistic and…

Converting positive and negative symptom scores between PANSS and SAPS/SANS.

PubMed

van Erp, Theo G M; Preda, Adrian; Nguyen, Dana; Faziola, Lawrence; Turner, Jessica; Bustillo, Juan; Belger, Aysenil; Lim, Kelvin O; McEwen, Sarah; Voyvodic, James; Mathalon, Daniel H; Ford, Judith; Potkin, Steven G; Fbirn

2014-01-01

The Scale for the Assessment of Positive Symptoms (SAPS), the Scale for the Assessment of Negative Symptoms (SANS), and the Positive and Negative Syndrome Scale for Schizophrenia (PANSS) are the most widely used schizophrenia symptom rating scales, but despite their co-existence for 25 years no easily usable between-scale conversion mechanism exists. The aim of this study was to provide equations for between-scale symptom rating conversions. Two-hundred-and-five schizophrenia patients [mean age±SD=39.5±11.6, 156 males] were assessed with the SANS, SAPS, and PANSS. Pearson's correlations between symptom scores from each of the scales were computed. Linear regression analyses, on data from 176 randomly selected patients, were performed to derive equations for converting ratings between the scales. Intraclass correlations, on data from the remaining 29 patients, not part of the regression analyses, were performed to determine rating conversion accuracy. Between-scale positive and negative symptom ratings were highly correlated. Intraclass correlations between the original positive and negative symptom ratings and those obtained via conversion of alternative ratings using the conversion equations were moderate to high (ICCs=0.65 to 0.91). Regression-based equations may be useful for conversion between schizophrenia symptom severity as measured by the SANS/SAPS and PANSS, though additional validation is warranted. This study's conversion equations, implemented at http:/converteasy.org, may aid in the comparison of medication efficacy studies, in meta- and mega-analyses examining symptoms as moderator variables, and in retrospective combination of symptom data in multi-center data sharing projects that need to pool symptom rating data when such data are obtained using different scales. Copyright © 2013 Elsevier B.V. All rights reserved.

Infant/Toddler Environment Rating Scale (ITERS-3). Third Edition

ERIC Educational Resources Information Center

Harms, Thelma; Cryer, Debby; Clifford, Richard M.; Yazejian, Noreen

2017-01-01

Building on extensive feedback from the field as well as vigorous new research on how best to support infant and toddler development and learning, the authors have revised and updated the widely used "Infant/Toddler Environment Rating Scale." ITERS-3 is the next-generation assessment tool for use in center-based child care programs for…

Behavioral and Emotional Strength-Based Assessment of Finnish Elementary Students: Psychometrics of the BERS-2

ERIC Educational Resources Information Center

Sointu, Erkko Tapio; Savolainen, Hannu; Lambert, Matthew C.; Lappalainen, Kristiina; Epstein, Michael H.

2014-01-01

When rating scales are used in different countries, thorough investigation of the psychometric properties is needed. We examined the internal structure of the Finnish translated Behavioral and Emotional Rating Scale-2 (BERS-2) using Rasch and confirmatory factor analysis approaches with a sample of youth, parents, and teachers. The results…

The Factor Structure and Sources of Variation Underlying the Social Learning Environment Rating Scales: Monograph 1.

ERIC Educational Resources Information Center

Warshow, Joyce P.; Bepko, Raymond A.

Seventeen intermediate level classes for the educable mentally retarded were involved in an investigation of the factor structure of the Social Learning Environment Rating Scale (SLERS), an instrument designed to quantify teacher-student behavior based on the Social Learning Curriculum (SLC). The 17 classes were observed implementing six…

Multi-Item Direct Behavior Ratings: Dependability of Two Levels of Assessment Specificity

ERIC Educational Resources Information Center

Volpe, Robert J.; Briesch, Amy M.

2015-01-01

Direct Behavior Rating-Multi-Item Scales (DBR-MIS) have been developed as formative measures of behavioral assessment for use in school-based problem-solving models. Initial research has examined the dependability of composite scores generated by summing all items comprising the scales. However, it has been argued that DBR-MIS may offer assessment…

Long-Term Outcomes in Children Diagnosed with Autism Spectrum Disorders in India.

PubMed

Mhatre, Dimpi; Bapat, Deepa; Udani, Vrajesh

2016-03-01

We investigated long-term outcomes in children with diagnosis of autism spectrum disorders based on Childhood Autism Rating Scale (CARS score). Information about outcomes such as speech, friendships and activities of daily living (ADLs) was collected through telephone-based interviews. Gilliam Autism Rating Scale-2 and Vineland Social Maturity Scale were used to assess level of functioning at follow-up. Parents of 80 [67 males, mean age 12 (3) years] children participated in the interview, 23 attended follow-up assessment. Sixty-four (80%) were verbal, 34 (42.5%) had need-based speech, 20 (25%) had friends and 37 (46%) had achieved age-appropriate ADLs. Median total follow-up period was 10 years. Lower disease severity, parent participation and higher maternal education were associated with better outcomes.

Homogenous Surface Nucleation of Solid Polar Stratospheric Cloud Particles

NASA Technical Reports Server (NTRS)

Tabazadeh, A.; Hamill, P.; Salcedo, D.; Gore, Warren J. (Technical Monitor)

2002-01-01

A general surface nucleation rate theory is presented for the homogeneous freezing of crystalline germs on the surfaces of aqueous particles. While nucleation rates in a standard classical homogeneous freezing rate theory scale with volume, the rates in a surface-based theory scale with surface area. The theory is used to convert volume-based information on laboratory freezing rates (in units of cu cm, seconds) of nitric acid trihydrate (NAT) and nitric acid dihydrate (NAD) aerosols into surface-based values (in units of sq cm, seconds). We show that a surface-based model is capable of reproducing measured nucleation rates of NAT and NAD aerosols from concentrated aqueous HNO3 solutions in the temperature range of 165 to 205 K. Laboratory measured nucleation rates are used to derive free energies for NAT and NAD germ formation in the stratosphere. NAD germ free energies range from about 23 to 26 kcal mole, allowing for fast and efficient homogeneous NAD particle production in the stratosphere. However, NAT germ formation energies are large (greater than 26 kcal mole) enough to prevent efficient NAT particle production in the stratosphere. We show that the atmospheric NAD particle production rates based on the surface rate theory are roughly 2 orders of magnitude larger than those obtained from a standard volume-based rate theory. Atmospheric volume and surface production of NAD particles will nearly cease in the stratosphere when denitrification in the air exceeds 40 and 78%, respectively. We show that a surface-based (volume-based) homogeneous freezing rate theory gives particle production rates, which are (not) consistent with both laboratory and atmospheric data on the nucleation of solid polar stratospheric cloud particles.

Reply to 'Comments on upscaling geochemical reaction rates usingpore-scale network modeling' by Peter C. Lichtner and Qinjun Kang

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Li; Peters, Catherine A.; Celia, Michael A.

2006-05-03

Our paper "Upscaling geochemical reaction rates usingpore-scale network modeling" presents a novel application of pore-scalenetwork modeling to upscale mineral dissolution and precipitationreaction rates from the pore scale to the continuum scale, anddemonstrates the methodology by analyzing the scaling behavior ofanorthite and kaolinite reaction kinetics under conditions related to CO2sequestration. We conclude that under highly acidic conditions relevantto CO2 sequestration, the traditional continuum-based methodology may notcapture the spatial variation in concentrations from pore to pore, andscaling tools may be important in correctly modeling reactive transportprocesses in such systems. This work addresses the important butdifficult question of scaling mineral dissolution and precipitationreactionmore » kinetics, which is often ignored in fields such as geochemistry,water resources, and contaminant hydrology. Although scaling of physicalprocesses has been studied for almost three decades, very few studieshave examined the scaling issues related to chemical processes, despitetheir importance in governing the transport and fate of contaminants insubsurface systems.« less

Pain point system scale (PPSS): a method for postoperative pain estimation in retrospective studies

PubMed Central

Gkotsi, Anastasia; Petsas, Dimosthenis; Sakalis, Vasilios; Fotas, Asterios; Triantafyllidis, Argyrios; Vouros, Ioannis; Saridakis, Evangelos; Salpiggidis, Georgios; Papathanasiou, Athanasios

2012-01-01

Purpose Pain rating scales are widely used for pain assessment. Nevertheless, a new tool is required for pain assessment needs in retrospective studies. Methods The postoperative pain episodes, during the first postoperative day, of three patient groups were analyzed. Each pain episode was assessed by a visual analog scale, numerical rating scale, verbal rating scale, and a new tool – pain point system scale (PPSS) – based on the analgesics administered. The type of analgesic was defined based on the authors’ clinic protocol, patient comorbidities, pain assessment tool scores, and preadministered medications by an artificial neural network system. At each pain episode, each patient was asked to fill the three pain scales. Bartlett’s test and Kaiser–Meyer–Olkin criterion were used to evaluate sample sufficiency. The proper scoring system was defined by varimax rotation. Spearman’s and Pearson’s coefficients assessed PPSS correlation to the known pain scales. Results A total of 262 pain episodes were evaluated in 124 patients. The PPSS scored one point for each dose of paracetamol, three points for each nonsteroidal antiinflammatory drug or codeine, and seven points for each dose of opioids. The correlation between the visual analog scale and PPSS was found to be strong and linear (rho: 0.715; P < 0.001 and Pearson: 0.631; P < 0.001). Conclusion PPSS correlated well with the known pain scale and could be used safely in the evaluation of postoperative pain in retrospective studies. PMID:23152699

Percolation transport theory and relevance to soil formation, vegetation growth, and productivity

NASA Astrophysics Data System (ADS)

Hunt, A. G.; Ghanbarian, B.

2016-12-01

Scaling laws of percolation theory have been applied to generate the time dependence of vegetation growth rates (both intensively managed and natural) and soil formation rates. The soil depth is thus equal to the solute vertical transport distance, the soil production function, chemical weathering rates, and C and N storage rates are all given by the time derivative of the soil depth. Approximate numerical coefficients based on the maximum flow rates in soils have been proposed, leading to a broad understanding of such processes. What is now required is an accurate understanding of the variability of the coefficients in the scaling relationships. The present abstract focuses on the scaling relationship for solute transport and soil formation. A soil formation rate relates length, x, and time, t, scales, meaning that the missing coefficient must include information about fundamental space and time scales, x0 and t0. x0 is proposed to be a fundamental mineral heterogeneity scale, i.e. a median particle diameter. to is then found from the ratio of x0 and a fundamental flow rate, v0, which is identified with the net infiltration rate. The net infiltration rate is equal to precipitation P less evapotranspiration, ET, plus run-on less run-off. Using this hypothesis, it is possible to predict soil depths and formation rates as functions of time and P - ET, and the formation rate as a function of depth, soil calcic and gypsic horizon depths as functions of P-ET. It is also possible to determine when soils are in equilibrium, and predict relationships of erosion rates and soil formation rates.

Does a web-based feedback training program result in improved reliability in clinicians' ratings of the Global Assessment of Functioning (GAF) Scale?

PubMed

Støre-Valen, Jakob; Ryum, Truls; Pedersen, Geir A F; Pripp, Are H; Jose, Paul E; Karterud, Sigmund

2015-09-01

The Global Assessment of Functioning (GAF) Scale is used in routine clinical practice and research to estimate symptom and functional severity and longitudinal change. Concerns about poor interrater reliability have been raised, and the present study evaluated the effect of a Web-based GAF training program designed to improve interrater reliability in routine clinical practice. Clinicians rated up to 20 vignettes online, and received deviation scores as immediate feedback (i.e., own scores compared with expert raters) after each rating. Growth curves of absolute SD scores across the vignettes were modeled. A linear mixed effects model, using the clinician's deviation scores from expert raters as the dependent variable, indicated an improvement in reliability during training. Moderation by content of scale (symptoms; functioning), scale range (average; extreme), previous experience with GAF rating, profession, and postgraduate training were assessed. Training reduced deviation scores for inexperienced GAF raters, for individuals in clinical professions other than nursing and medicine, and for individuals with no postgraduate specialization. In addition, training was most beneficial for cases with average severity of symptoms compared with cases with extreme severity. The results support the use of Web-based training with feedback routines as a means to improve the reliability of GAF ratings performed by clinicians in mental health practice. These results especially pertain to clinicians in mental health practice who do not have a masters or doctoral degree. (c) 2015 APA, all rights reserved.

Atmosphere

NASA Astrophysics Data System (ADS)

Ghosh, D.; Mitra, S. K.

2014-05-01

This paper investigates the high-temperature corrosion behavior of microstructurally different regions of the weldment of 9 Cr-1 Mo steel used in thermal power plant boiler in SO2 + O2 environment. The weldment is produced by tungsten inert gas welding method, and the different regions of the weldment (weld metal, heat-affected zone, and base metal) are exposed in SO2 + O2 (ratio 2:1) environment at 973 K for 120 h. The reaction kinetics and corrosion growth rate of different regions of weldment in isothermal condition are evaluated. The post corroded scales of the different specimens are studied in SEM, EDS, and XRD. The results indicate that the weld metal shows higher corrosion rate followed by HAZ and base metal. The higher rate of corrosion of weldmetal is mainly attributed to the least protective inner scale of Cr2O3 with minimum Cr Content. This is due to the formation of delta ferrite, which leads to the precipitation of the Cr-based secondary phases and depletes the free Cr from the matrix. The thermal cycles during welding at high temperature are favorable for the formation of delta ferrite. On the other hand, in absence of delta ferrite, the base metal and HAZ regions of the weldment show lower corrosion rate than weld metal. The difference in corrosion rate in the three regions of the weldment is supplemented by post-corroded scale characterizations.

Development of a behaviour-based measurement tool with defined intervention level for assessing acute pain in cats.

PubMed

Calvo, G; Holden, E; Reid, J; Scott, E M; Firth, A; Bell, A; Robertson, S; Nolan, A M

2014-12-01

To develop a composite measure pain scale tool to assess acute pain in cats and derive an intervention score. To develop the prototype composite measure pain scale-feline, words describing painful cats were collected, grouped into behavioural categories and ranked. To assess prototype validity two observers independently assigned composite measure pain scale-feline and numerical rating scale scores to 25 hospitalised cats before and after analgesic treatment. Following interim analysis the prototype was revised (revised composite measure pain scale-feline). To determine intervention score, two observers independently assigned revised composite measure pain scale-feline and numerical rating scale scores to 116 cats. A further observer, a veterinarian, stated whether analgesia was necessary. Mean ± sd decrease in revised composite measure pain scale-feline and numerical rating scale scores following analgesia were 2 · 4 ± 2 · 87 and 1 · 9 ± 2 · 34, respectively (95% confidence interval for mean change in revised composite measure pain scale-feline between 1 · 21 and 3 · 6). Changes in revised composite measure pain scale-feline and numerical rating scale were significantly correlated (r = 0 · 8) (P < 0001). Intervention level score of ≥4/16 was derived for revised composite measure pain scale-feline (26 · 7% misclassification) and ≥3/10 for numerical rating scale (14 · 5% misclassification). A valid instrument with a recommended analgesic intervention level has been developed to assess acute clinical pain in cats that should be readily applicable in practice. © 2014 British Small Animal Veterinary Association.

Capturing the true burden of dystonia on patients: the Cervical Dystonia Impact Profile (CDIP-58).

PubMed

Cano, S J; Warner, T T; Linacre, J M; Bhatia, K P; Thompson, A J; Fitzpatrick, R; Hobart, J C

2004-11-09

To develop a new rating scale for measuring the health impact of cervical dystonia (CD) that includes patients' perceptions and complements existing observer dependent clinician rating scales. Scale development was in three stages. In Stage 1, a large pool of items was generated from patient interviews (n = 25), expert opinion, and literature review. In Stage 2, these items were administered by postal survey to people with CD. The resulting data were analyzed using Rasch item analysis to construct, from the item pool, a rating scale that satisfied criteria for rigorous measurement. In Stage 3, the measurement properties of this rating scale were examined in an independent sample of people with CD. In Stage 1, 150 items concerning the health impact of CD were generated. In Stage 2, 556 people completed questionnaires (87% response rate) and a 58-item rating scale measuring the health impact of CD in eight areas was constructed (CD Impact Profile, CDIP-58). In Stage 3, CDIP-58 data from 391 people (87% response rate) were received. Analyses supported the measurement of eight unidimensional constructs (infit mean square range 0.62 to 1.50), item calibration (33.37 to 67.56), and patient separation statistics (2.59 to 3.38). Items demonstrated stable calibrations in subgroups of people with CD supporting the stability of the CDIP-58. The CDIP-58 is a reliable and valid patient-based rating scale measuring the health impact of CD in eight health dimensions.

A Bayesian Hierarchical Modeling Scheme for Estimating Erosion Rates Under Current Climate Conditions

NASA Astrophysics Data System (ADS)

Lowman, L.; Barros, A. P.

2014-12-01

Computational modeling of surface erosion processes is inherently difficult because of the four-dimensional nature of the problem and the multiple temporal and spatial scales that govern individual mechanisms. Landscapes are modified via surface and fluvial erosion and exhumation, each of which takes place over a range of time scales. Traditional field measurements of erosion/exhumation rates are scale dependent, often valid for a single point-wise location or averaging over large aerial extents and periods with intense and mild erosion. We present a method of remotely estimating erosion rates using a Bayesian hierarchical model based upon the stream power erosion law (SPEL). A Bayesian approach allows for estimating erosion rates using the deterministic relationship given by the SPEL and data on channel slopes and precipitation at the basin and sub-basin scale. The spatial scale associated with this framework is the elevation class, where each class is characterized by distinct morphologic behavior observed through different modes in the distribution of basin outlet elevations. Interestingly, the distributions of first-order outlets are similar in shape and extent to the distribution of precipitation events (i.e. individual storms) over a 14-year period between 1998-2011. We demonstrate an application of the Bayesian hierarchical modeling framework for five basins and one intermontane basin located in the central Andes between 5S and 20S. Using remotely sensed data of current annual precipitation rates from the Tropical Rainfall Measuring Mission (TRMM) and topography from a high resolution (3 arc-seconds) digital elevation map (DEM), our erosion rate estimates are consistent with decadal-scale estimates based on landslide mapping and sediment flux observations and 1-2 orders of magnitude larger than most millennial and million year timescale estimates from thermochronology and cosmogenic nuclides.

Experimental Study on Hot Metal Desulfurization Using Sintered Red Mud-Based Flux

NASA Astrophysics Data System (ADS)

Li, Fengshan; Zhang, Yanling; Guo, Zhancheng

2017-09-01

This research presents the results of laboratory and pilot-scale tests conducted on the use of sintered red mud (RM)-based flux in the hot metal desulfurization (HMD) process. Al2O3/Na2O in RM can decrease the melting point of lime-based slag and can work as a flux in the HMD process. Good slag fluidity was observed throughout the process, and high desulfurization rates ( 80%) with a low final S content (<0.02%) were experimentally obtained when the RM:CaO ratio was between 1.2:1 and 2.4:1. The pilot-scale test results indicated that a desulfurization rate as high as 91% and a S content <0.0099% could be acquired when RM:lime = 1:1, verifying the feasibility of using sintered RM-based flux in HMD. The data obtained provide important information for promoting the large-scale application of sintered RM in steelmaking.

Application of psychometric theory to the measurement of voice quality using rating scales.

PubMed

Shrivastav, Rahul; Sapienza, Christine M; Nandur, Vuday

2005-04-01

Rating scales are commonly used to study voice quality. However, recent research has demonstrated that perceptual measures of voice quality obtained using rating scales suffer from poor interjudge agreement and reliability, especially in the mid-range of the scale. These findings, along with those obtained using multidimensional scaling (MDS), have been interpreted to show that listeners perceive voice quality in an idiosyncratic manner. Based on psychometric theory, the present research explored an alternative explanation for the poor interlistener agreement observed in previous research. This approach suggests that poor agreement between listeners may result, in part, from measurement errors related to a variety of factors rather than true differences in the perception of voice quality. In this study, 10 listeners rated breathiness for 27 vowel stimuli using a 5-point rating scale. Each stimulus was presented to the listeners 10 times in random order. Interlistener agreement and reliability were calculated from these ratings. Agreement and reliability were observed to improve when multiple ratings of each stimulus from each listener were averaged and when standardized scores were used instead of absolute ratings. The probability of exact agreement was found to be approximately .9 when using averaged ratings and standardized scores. In contrast, the probability of exact agreement was only .4 when a single rating from each listener was used to measure agreement. These findings support the hypothesis that poor agreement reported in past research partly arises from errors in measurement rather than individual differences in the perception of voice quality.

The Koukopoulos Mixed Depression Rating Scale (KMDRS): An International Mood Network (IMN) validation study of a new mixed mood rating scale.

PubMed

Sani, Gabriele; Vöhringer, Paul A; Barroilhet, Sergio A; Koukopoulos, Alexia E; Ghaemi, S Nassir

2018-05-01

It has been proposed that the broad major depressive disorder (MDD) construct is heterogenous. Koukopoulos has provided diagnostic criteria for an important subtype within that construct, "mixed depression" (MxD), which encompasses clinical pictures characterized by marked psychomotor or inner excitation and rage/anger, along with severe depression. This study provides psychometric validation for the first rating scale specifically designed to assess MxD symptoms cross-sectionally, the Koukopoulos Mixed Depression Rating Scale (KMDRS). 350 patients from the international mood network (IMN) completed three rating scales: the KMDRS, Montgomery-Asberg Depression Rating Scale (MADRS) and Young Mania Rating Scale (YMRS). KMDRS' psychometric properties assessed included Cronbach's alpha, inter-rater reliability, factor analysis, predictive validity, and Receiver Operator Curve analysis. Internal consistency (Cronbach's alpha = 0.76; 95% CI 0.57, 0.94) and interrater reliability (kappa = 0.73) were adequate. Confirmatory factor analysis identified 2 components: anger and psychomotor excitation (80% of total variance). Good predictive validity was seen (C-statistic = 0.82 95% CI 0.68, 0.93). Severity cut-off scores identified were as follows: none (0-4), possible (5-9), mild (10-15), moderate (16-20) and severe (> 21) MxD. Non DSM-based diagnosis of MxD may pose some difficulties in the initial use and interpretation of the scoring of the scale. Moreover, the cross-sectional nature of the evaluation does not verify the long-term stability of the scale. KMDRS was a reliable and valid instrument to assess MxD symptoms. Copyright © 2018 Elsevier B.V. All rights reserved.

Multi-scale Modeling of the Impact Response of a Strain Rate Sensitive High-Manganese Austenitic Steel

NASA Astrophysics Data System (ADS)

Önal, Orkun; Ozmenci, Cemre; Canadinc, Demircan

2014-09-01

A multi-scale modeling approach was applied to predict the impact response of a strain rate sensitive high-manganese austenitic steel. The roles of texture, geometry and strain rate sensitivity were successfully taken into account all at once by coupling crystal plasticity and finite element (FE) analysis. Specifically, crystal plasticity was utilized to obtain the multi-axial flow rule at different strain rates based on the experimental deformation response under uniaxial tensile loading. The equivalent stress - equivalent strain response was then incorporated into the FE model for the sake of a more representative hardening rule under impact loading. The current results demonstrate that reliable predictions can be obtained by proper coupling of crystal plasticity and FE analysis even if the experimental flow rule of the material is acquired under uniaxial loading and at moderate strain rates that are significantly slower than those attained during impact loading. Furthermore, the current findings also demonstrate the need for an experiment-based multi-scale modeling approach for the sake of reliable predictions of the impact response.

Recent topographic evolution and erosion of the deglaciated Washington Cascades inferred from a stochastic landscape evolution model

NASA Astrophysics Data System (ADS)

Moon, Seulgi; Shelef, Eitan; Hilley, George E.

2015-05-01

In this study, we model postglacial surface processes and examine the evolution of the topography and denudation rates within the deglaciated Washington Cascades to understand the controls on and time scales of landscape response to changes in the surface process regime after deglaciation. The postglacial adjustment of this landscape is modeled using a geomorphic-transport-law-based numerical model that includes processes of river incision, hillslope diffusion, and stochastic landslides. The surface lowering due to landslides is parameterized using a physically based slope stability model coupled to a stochastic model of the generation of landslides. The model parameters of river incision and stochastic landslides are calibrated based on the rates and distribution of thousand-year-time scale denudation rates measured from cosmogenic 10Be isotopes. The probability distributions of those model parameters calculated based on a Bayesian inversion scheme show comparable ranges from previous studies in similar rock types and climatic conditions. The magnitude of landslide denudation rates is determined by failure density (similar to landslide frequency), whereas precipitation and slopes affect the spatial variation in landslide denudation rates. Simulation results show that postglacial denudation rates decay over time and take longer than 100 kyr to reach time-invariant rates. Over time, the landslides in the model consume the steep slopes characteristic of deglaciated landscapes. This response time scale is on the order of or longer than glacial/interglacial cycles, suggesting that frequent climatic perturbations during the Quaternary may produce a significant and prolonged impact on denudation and topography.

The Dynamics of Scaling: A Memory-Based Anchor Model of Category Rating and Absolute Identification

ERIC Educational Resources Information Center

Petrov, Alexander A.; Anderson, John R.

2005-01-01

A memory-based scaling model--ANCHOR--is proposed and tested. The perceived magnitude of the target stimulus is compared with a set of anchors in memory. Anchor selection is probabilistic and sensitive to similarity, base-level strength, and recency. The winning anchor provides a reference point near the target and thereby converts the global…

New, national bottom-up estimate for tree-based biological ...

EPA Pesticide Factsheets

Nitrogen is a limiting nutrient in many ecosystems, but is also a chief pollutant from human activity. Quantifying human impacts on the nitrogen cycle and investigating natural ecosystem nitrogen cycling both require an understanding of the magnitude of nitrogen inputs from biological nitrogen fixation (BNF). A bottom-up approach to estimating BNF—scaling rates up from measurements to broader scales—is attractive because it is rooted in actual BNF measurements. However, bottom-up approaches have been hindered by scaling difficulties, and a recent top-down approach suggested that the previous bottom-up estimate was much too large. Here, we used a bottom-up approach for tree-based BNF, overcoming scaling difficulties with the systematic, immense (>70,000 N-fixing trees) Forest Inventory and Analysis (FIA) database. We employed two approaches to estimate species-specific BNF rates: published ecosystem-scale rates (kg N ha-1 yr-1) and published estimates of the percent of N derived from the atmosphere (%Ndfa) combined with FIA-derived growth rates. Species-specific rates can vary for a variety of reasons, so for each approach we examined how different assumptions influenced our results. Specifically, we allowed BNF rates to vary with stand age, N-fixer density, and canopy position (since N-fixation is known to require substantial light).Our estimates from this bottom-up technique are several orders of magnitude lower than previous estimates indicating

The TRMM Multi-satellite Precipitation Analysis (TMPA): Quasi-Global Precipitation Estimates at Fine Scales

NASA Technical Reports Server (NTRS)

Huffman, George J.; Adler, Robert F.; Bolvin, David T.; Gu, Guojun; Nelkin, Eric J.; Bowman, Kenneth P.; Stocker, Erich; Wolff, David B.

2006-01-01

The TRMM Multi-satellite Precipitation Analysis (TMPA) provides a calibration-based sequential scheme for combining multiple precipitation estimates from satellites, as well as gauge analyses where feasible, at fine scales (0.25 degrees x 0.25 degrees and 3-hourly). It is available both after and in real time, based on calibration by the TRMM Combined Instrument and TRMM Microwave Imager precipitation products, respectively. Only the after-real-time product incorporates gauge data at the present. The data set covers the latitude band 50 degrees N-S for the period 1998 to the delayed present. Early validation results are as follows: The TMPA provides reasonable performance at monthly scales, although it is shown to have precipitation rate dependent low bias due to lack of sensitivity to low precipitation rates in one of the input products (based on AMSU-B). At finer scales the TMPA is successful at approximately reproducing the surface-observation-based histogram of precipitation, as well as reasonably detecting large daily events. The TMPA, however, has lower skill in correctly specifying moderate and light event amounts on short time intervals, in common with other fine-scale estimators. Examples are provided of a flood event and diurnal cycle determination.

Delphi Rating on the Internet

PubMed Central

Deshpande, Aniruddha M.; Shiffman, Richard N.

2003-01-01

We designed an application to allow respondents to rate components of clinical guidelines on the Internet. Twenty-three invited experts completed the rating followed by a satisfaction survey using a 5-level Likert scale. The experts felt that Web data entry was convenient, acceptable and easily accessible. We conclude that Web-based Delphi rating for consensus development is a convenient and acceptable alternative to the traditional paper-based method. PMID:14728333

Pre-Stressing Micron-Scale Aluminum Core-Shell Particles to Improve Reactivity

PubMed Central

Levitas, Valery I.; McCollum, Jena; Pantoya, Michelle

2015-01-01

The main direction in increasing reactivity of aluminum (Al) particles for energetic applications is reduction in their size down to nanoscale. However, Al nanoparticles are 30–50 times more expensive than micron scale particles and possess safety and environmental issues. Here, we improved reactivity of Al micron scale particles by synthesizing pre-stressed core-shell structures. Al particles were annealed and quenched to induce compressive stresses in the alumina passivation shell surrounding Al core. This thermal treatment was designed based on predictions of the melt-dispersion mechanism (MDM); a theory describing Al particle reaction under high heating rate. For all anneal treatment temperatures, experimental flame propagation rates for Al combined with nanoscale copper oxide (CuO) are in quantitative agreement with the theoretical predictions based on the MDM. The best treatment increases flame rate by 36% and achieves 68% of that for the best Al nanoparticles. PMID:25597747

Pilot-scale biopesticide production by Bacillus thuringiensis subsp. kurstaki using starch industry wastewater as raw material.

PubMed

Ndao, Adama; Sellamuthu, Balasubramanian; Gnepe, Jean R; Tyagi, Rajeshwar D; Valero, Jose R

2017-09-02

Pilot-scale Bacillus thuringiensis based biopesticide production (2000 L bioreactor) was conducted using starch industry wastewater (SIW) as a raw material using optimized operational parameters obtained in 15 L and 150 L fermenters. In pilot scale fermentation process the oxygen transfer rate is a major limiting factor for high product yield. Thus, the volumetric mass transfer coefficient (K L a) remains a tool to determine the oxygen transfer capacity [oxygen utilization rate (OUR) and oxygen transfer rate (OTR)] to obtain better bacterial growth rate and entomotoxicity in new bioreactor process optimization and scale-up. This study results demonstrated that the oxygen transfer rate in 2000 L bioreactor was better than 15 L and 150 L fermenters. The better oxygen transfer in 2000 L bioreactor augmented the bacterial growth [total cell (TC) and viable spore count (SC)] and delta-endotoxin yield. Prepared a stable biopesticide formulation for field use and its entomotoxicity was also evaluated. This study result corroborates the feasibility of industrial scale operation of biopesticide production using starch industry wastewater as raw material.

Empathy, Self-Reflection, and Curriculum Choice

ERIC Educational Resources Information Center

Grosseman, Suely; Hojat, Mohammadreza; Duke, Pamela M.; Mennin, Stewart; Rosenzweig, Steven; Novack, Dennis

2014-01-01

We administered the Jefferson Scale of Empathy and the Groningen Reflection Ability Scale to 61 of 64 entering medical students who self-selected a problem-based learning curricular track and to 163 of 198 who self-selected a lecture-based track (response rates of 95.3% and 82.3%, respectively, with no statistically significant differences in mean…

RADSOURCE. Volume 1, Part 1, A scaling factor prediction computer program technical manual and code validation: Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vance, J.N.; Holderness, J.H.; James, D.W.

1992-12-01

Waste stream scaling factors based on sampling programs are vulnerable to one or more of the following factors: sample representativeness, analytic accuracy, and measurement sensitivity. As an alternative to sample analyses or as a verification of the sampling results, this project proposes the use of the RADSOURCE code, which accounts for the release of fuel-source radionuclides. Once the release rates of these nuclides from fuel are known, the code develops scaling factors for waste streams based on easily measured Cobalt-60 (Co-60) and Cesium-137 (Cs-137). The project team developed mathematical models to account for the appearance rate of 10CFR61 radionuclides inmore » reactor coolant. They based these models on the chemistry and nuclear physics of the radionuclides involved. Next, they incorporated the models into a computer code that calculates plant waste stream scaling factors based on reactor coolant gamma- isotopic data. Finally, the team performed special sampling at 17 reactors to validate the models in the RADSOURCE code.« less

Empirically based assessment and taxonomy of psychopathology for ages 1½-90+ years: Developmental, multi-informant, and multicultural findings.

PubMed

Achenbach, Thomas M; Ivanova, Masha Y; Rescorla, Leslie A

2017-11-01

Originating in the 1960s, the Achenbach System of Empirically Based Assessment (ASEBA) comprises a family of instruments for assessing problems and strengths for ages 1½-90+ years. To provide an overview of the ASEBA, related research, and future directions for empirically based assessment and taxonomy. Standardized, multi-informant ratings of transdiagnostic dimensions of behavioral, emotional, social, and thought problems are hierarchically scored on narrow-spectrum syndrome scales, broad-spectrum internalizing and externalizing scales, and a total problems (general psychopathology) scale. DSM-oriented and strengths scales are also scored. The instruments and scales have been iteratively developed from assessments of clinical and population samples of hundreds of thousands of individuals. Items, instruments, scales, and norms are tailored to different kinds of informants for ages 1½-5, 6-18, 18-59, and 60-90+ years. To take account of differences between informants' ratings, parallel instruments are completed by parents, teachers, youths, adult probands, and adult collaterals. Syndromes and Internalizing/Externalizing scales derived from factor analyses of each instrument capture variations in patterns of problems that reflect different informants' perspectives. Confirmatory factor analyses have supported the syndrome structures in dozens of societies. Software displays scale scores in relation to user-selected multicultural norms for the age and gender of the person being assessed, according to ratings by each type of informant. Multicultural norms are derived from population samples in 57 societies on every inhabited continent. Ongoing and future research includes multicultural assessment of elders; advancing transdiagnostic progress and outcomes assessment; and testing higher order structures of psychopathology. Copyright © 2017 Elsevier Inc. All rights reserved.

Investigator Ratings of ADHD Symptoms during a Randomized, Placebo-Controlled Trial of Atomoxetine: A Comparison of Parents and Teachers as Informants

ERIC Educational Resources Information Center

Bohnstedt, Bradley N.; Kronenberger, William G.; Dunn, David W.; Giauque, Ann L.; Wood, Elisabeth A.; Rembusch, Mary E.; Lafata, Deborah

2005-01-01

This study compared investigator ratings of ADHD symptoms based on interviews with parents and teachers during a doubleblind, placebo-controlled study of atomoxetine. Investigators completed the ADHD Rating Scale: Investigator (ADHDRS-I) based on separate semistructured interviews with the primary caretaker and teacher of the participant.…

A positive take on schizophrenia negative symptom scales: Converting scores between the SANS, NSA and SDS.

PubMed

Preda, Adrian; Nguyen, Dana D; Bustillo, Juan R; Belger, Aysenil; O'Leary, Daniel S; McEwen, Sarah; Ling, Shichun; Faziola, Lawrence; Mathalon, Daniel H; Ford, Judith M; Potkin, Steven G; van Erp, Theo G M

2018-06-20

To provide quantitative conversions between commonly used scales for the assessment of negative symptoms in schizophrenia. Linear regression analyses generated conversion equations between symptom scores from the Scale for the Assessment of Negative Symptoms (SANS), the Schedule for the Deficit Syndrome (SDS), the Positive and Negative Syndrome Scale (PANSS), or the Negative Symptoms Assessment (NSA) based on a cross sectional sample of 176 individuals with schizophrenia. Intraclass correlations assessed the rating conversion accuracy based on a separate sub-sample of 29 patients who took part in the initial study as well as an independent sample of 28 additional subjects with schizophrenia. Between-scale negative symptom ratings were moderately to highly correlated (r = 0.73-0.91). Intraclass correlations between the original negative symptom rating scores and those obtained via using the conversion equations were in the range of 0.61-0.79. While there is a degree of non-overlap, several negative symptoms scores reflect measures of similar constructs and may be reliably converted between some scales. The conversion equations are provided at http://www.converteasy.org and may be used for meta- and mega-analyses that examine negative symptoms. Copyright © 2018 Elsevier B.V. All rights reserved.

Compression based entropy estimation of heart rate variability on multiple time scales.

PubMed

Baumert, Mathias; Voss, Andreas; Javorka, Michal

2013-01-01

Heart rate fluctuates beat by beat in a complex manner. The aim of this study was to develop a framework for entropy assessment of heart rate fluctuations on multiple time scales. We employed the Lempel-Ziv algorithm for lossless data compression to investigate the compressibility of RR interval time series on different time scales, using a coarse-graining procedure. We estimated the entropy of RR interval time series of 20 young and 20 old subjects and also investigated the compressibility of randomly shuffled surrogate RR time series. The original RR time series displayed significantly smaller compression entropy values than randomized RR interval data. The RR interval time series of older subjects showed significantly different entropy characteristics over multiple time scales than those of younger subjects. In conclusion, data compression may be useful approach for multiscale entropy assessment of heart rate variability.

Examining the validity and reliability of the Taita symptom checklist using Rasch analysis.

PubMed

Chen, Yun-Ling; Pan, Ay-Woan; Chung, LyInn; Chen, Tsyr-Jang

2015-03-01

The Taita symptom checklist (TSCL) is a standardized self-rating psychiatric symptom scale for outpatients with mental illness in Taiwan. This study aimed to examine the validity and reliability of the TSCL using Rasch analysis. The TSCL was given to 583 healthy people and 479 people with mental illness. Rasch analysis was used to examine the appropriateness of the rating scale, the unidimensionality of the scale, the differential item functioning across sex and diagnosis, and the Rasch cut-off score of the scale. Rasch analysis confirmed that the revised 37 items with a three-point rating scale of the TSCL demonstrated good internal consistency and met criteria for unidimensionality. The person and item reliability indices were high. The TSCL could reliably measure healthy participants and patients with mental illness. Differential item functioning due to sex or psychiatric diagnosis was evident for three items. A Rasch cut-off score for TSCL was produced for detecting participants' psychiatric symptoms based on an eight-level classification. The TSCL is a reliable and valid assessment to evaluate the participants' perceived disturbance of psychiatric symptoms based on Rasch analysis. Copyright © 2013. Published by Elsevier B.V.

Scaling in situ cosmogenic nuclide production rates using analytical approximations to atmospheric cosmic-ray fluxes

NASA Astrophysics Data System (ADS)

Lifton, Nathaniel; Sato, Tatsuhiko; Dunai, Tibor J.

2014-01-01

Several models have been proposed for scaling in situ cosmogenic nuclide production rates from the relatively few sites where they have been measured to other sites of interest. Two main types of models are recognized: (1) those based on data from nuclear disintegrations in photographic emulsions combined with various neutron detectors, and (2) those based largely on neutron monitor data. However, stubborn discrepancies between these model types have led to frequent confusion when calculating surface exposure ages from production rates derived from the models. To help resolve these discrepancies and identify the sources of potential biases in each model, we have developed a new scaling model based on analytical approximations to modeled fluxes of the main atmospheric cosmic-ray particles responsible for in situ cosmogenic nuclide production. Both the analytical formulations and the Monte Carlo model fluxes on which they are based agree well with measured atmospheric fluxes of neutrons, protons, and muons, indicating they can serve as a robust estimate of the atmospheric cosmic-ray flux based on first principles. We are also using updated records for quantifying temporal and spatial variability in geomagnetic and solar modulation effects on the fluxes. A key advantage of this new model (herein termed LSD) over previous Monte Carlo models of cosmogenic nuclide production is that it allows for faster estimation of scaling factors based on time-varying geomagnetic and solar inputs. Comparing scaling predictions derived from the LSD model with those of previously published models suggest potential sources of bias in the latter can be largely attributed to two factors: different energy responses of the secondary neutron detectors used in developing the models, and different geomagnetic parameterizations. Given that the LSD model generates flux spectra for each cosmic-ray particle of interest, it is also relatively straightforward to generate nuclide-specific scaling factors based on recently updated neutron and proton excitation functions (probability of nuclide production in a given nuclear reaction as a function of energy) for commonly measured in situ cosmogenic nuclides. Such scaling factors reflect the influence of the energy distribution of the flux folded with the relevant excitation functions. Resulting scaling factors indicate 3He shows the strongest positive deviation from the flux-based scaling, while 14C exhibits a negative deviation. These results are consistent with a recent Monte Carlo-based study using a different cosmic-ray physics code package but the same excitation functions.

A novel bench-scale column assay to investigate site-specific nitrification biokinetics in biological rapid sand filters.

PubMed

Tatari, K; Smets, B F; Albrechtsen, H-J

2013-10-15

A bench-scale assay was developed to obtain site-specific nitrification biokinetic information from biological rapid sand filters employed in groundwater treatment. The experimental set-up uses granular material subsampled from a full-scale filter, packed in a column, and operated with controlled and continuous hydraulic and ammonium loading. Flowrates and flow recirculation around the column are chosen to mimic full-scale hydrodynamic conditions, and minimize axial gradients. A reference ammonium loading rate is calculated based on the average loading experienced in the active zone of the full-scale filter. Effluent concentrations of ammonium are analyzed when the bench-scale column is subject to reference loading, from which removal rates are calculated. Subsequently, removal rates above the reference loading are measured by imposing short-term loading variations. A critical loading rate corresponding to the maximum removal rate can be inferred. The assay was successfully applied to characterize biokinetic behavior from a test rapid sand filter; removal rates at reference loading matched those observed from full-scale observations, while a maximum removal capacity of 6.9 g NH4(+)-N/m(3) packed sand/h could easily be determined at 7.5 g NH4(+)-N/m(3) packed sand/h. This assay, with conditions reflecting full-scale observations, and where the biological activity is subject to minimal physical disturbance, provides a simple and fast, yet powerful tool to gain insight in nitrification kinetics in rapid sand filters. Copyright © 2013 Elsevier Ltd. All rights reserved.

Distance-Learning, ADHD Quality Improvement in Primary Care: A Cluster-Randomized Trial.

PubMed

Fiks, Alexander G; Mayne, Stephanie L; Michel, Jeremy J; Miller, Jeffrey; Abraham, Manju; Suh, Andrew; Jawad, Abbas F; Guevara, James P; Grundmeier, Robert W; Blum, Nathan J; Power, Thomas J

2017-10-01

To evaluate a distance-learning, quality improvement intervention to improve pediatric primary care provider use of attention-deficit/hyperactivity disorder (ADHD) rating scales. Primary care practices were cluster randomized to a 3-part distance-learning, quality improvement intervention (web-based education, collaborative consultation with ADHD experts, and performance feedback reports/calls), qualifying for Maintenance of Certification (MOC) Part IV credit, or wait-list control. We compared changes relative to a baseline period in rating scale use by study arm using logistic regression clustered by practice (primary analysis) and examined effect modification by level of clinician participation. An electronic health record-linked system for gathering ADHD rating scales from parents and teachers was implemented before the intervention period at all sites. Rating scale use was ascertained by manual chart review. One hundred five clinicians at 19 sites participated. Differences between arms were not significant. From the baseline to intervention period and after implementation of the electronic system, clinicians in both study arms were significantly more likely to administer and receive parent and teacher rating scales. Among intervention clinicians, those who participated in at least 1 feedback call or qualified for MOC credit were more likely to give parents rating scales with differences of 14.2 (95% confidence interval [CI], 0.6-27.7) and 18.8 (95% CI, 1.9-35.7) percentage points, respectively. A 3-part clinician-focused distance-learning, quality improvement intervention did not improve rating scale use. Complementary strategies that support workflows and more fully engage clinicians may be needed to bolster care. Electronic systems that gather rating scales may help achieve this goal. Index terms: ADHD, primary care, quality improvement, clinical decision support.

Grain-Size Based Additivity Models for Scaling Multi-rate Uranyl Surface Complexation in Subsurface Sediments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Xiaoying; Liu, Chongxuan; Hu, Bill X.

The additivity model assumed that field-scale reaction properties in a sediment including surface area, reactive site concentration, and reaction rate can be predicted from field-scale grain-size distribution by linearly adding reaction properties estimated in laboratory for individual grain-size fractions. This study evaluated the additivity model in scaling mass transfer-limited, multi-rate uranyl (U(VI)) surface complexation reactions in a contaminated sediment. Experimental data of rate-limited U(VI) desorption in a stirred flow-cell reactor were used to estimate the statistical properties of the rate constants for individual grain-size fractions, which were then used to predict rate-limited U(VI) desorption in the composite sediment. The resultmore » indicated that the additivity model with respect to the rate of U(VI) desorption provided a good prediction of U(VI) desorption in the composite sediment. However, the rate constants were not directly scalable using the additivity model. An approximate additivity model for directly scaling rate constants was subsequently proposed and evaluated. The result found that the approximate model provided a good prediction of the experimental results within statistical uncertainty. This study also found that a gravel-size fraction (2 to 8 mm), which is often ignored in modeling U(VI) sorption and desorption, is statistically significant to the U(VI) desorption in the sediment.« less

Performance-based tests versus behavioral ratings in the assessment of executive functioning in preschoolers: associations with ADHD symptoms and reading achievement.

PubMed

Miranda, Ana; Colomer, Carla; Mercader, Jessica; Fernández, M Inmaculada; Presentación, M Jesús

2015-01-01

The early assessment of the executive processes using ecologically valid instruments is essential for identifying deficits and planning actions to deal with possible adverse consequences. The present study has two different objectives. The first objective is to analyze the relationship between preschoolers' performance on tests of Working Memory and Inhibition and parents' and teachers' ratings of these executive functions (EFs) using the Behavior Rating Inventory of Executive Function (BRIEF). The second objective consists of studying the predictive value of the different EF measures (performance-based test and rating scales) on Inattention and Hyperactivity/Impulsivity behaviors and on indicators of word reading performance. The participants in the study were 209 children in the last year of preschool, their teachers and their families. Performance-based tests of Working Memory and Inhibition were administered, as well as word reading measures (accuracy and speed). The parents and teachers filled out rating scales of the EF and typical behaviors of attention deficit hyperactivity disorder (ADHD) symptomatology. Moderate correlation values were found between the different EF assessments procedures, although the results varied depending on the different domains. Metacognition Index from the BRIEF presented stronger correlations with verbal working memory tests than with inhibition tests. Both the rating scales and the performance-based tests were significant predictors of Inattention and Hyperactivity/Impulsivity behaviors and the reading achievement measures. However, the BRIEF explained a greater percentage of variance in the case of the ADHD symptomatology, while the performance-based tests explained reading achievement to a greater degree. The implications of the findings for research and clinical practice are discussed.

Performance-based tests versus behavioral ratings in the assessment of executive functioning in preschoolers: associations with ADHD symptoms and reading achievement

PubMed Central

Miranda, Ana; Colomer, Carla; Mercader, Jessica; Fernández, M. Inmaculada; Presentación, M. Jesús

2015-01-01

The early assessment of the executive processes using ecologically valid instruments is essential for identifying deficits and planning actions to deal with possible adverse consequences. The present study has two different objectives. The first objective is to analyze the relationship between preschoolers’ performance on tests of Working Memory and Inhibition and parents’ and teachers’ ratings of these executive functions (EFs) using the Behavior Rating Inventory of Executive Function (BRIEF). The second objective consists of studying the predictive value of the different EF measures (performance-based test and rating scales) on Inattention and Hyperactivity/Impulsivity behaviors and on indicators of word reading performance. The participants in the study were 209 children in the last year of preschool, their teachers and their families. Performance-based tests of Working Memory and Inhibition were administered, as well as word reading measures (accuracy and speed). The parents and teachers filled out rating scales of the EF and typical behaviors of attention deficit hyperactivity disorder (ADHD) symptomatology. Moderate correlation values were found between the different EF assessments procedures, although the results varied depending on the different domains. Metacognition Index from the BRIEF presented stronger correlations with verbal working memory tests than with inhibition tests. Both the rating scales and the performance-based tests were significant predictors of Inattention and Hyperactivity/Impulsivity behaviors and the reading achievement measures. However, the BRIEF explained a greater percentage of variance in the case of the ADHD symptomatology, while the performance-based tests explained reading achievement to a greater degree. The implications of the findings for research and clinical practice are discussed. PMID:25972833

Fundamental insights into ontogenetic growth from theory and fish.

PubMed

Sibly, Richard M; Baker, Joanna; Grady, John M; Luna, Susan M; Kodric-Brown, Astrid; Venditti, Chris; Brown, James H

2015-11-10

The fundamental features of growth may be universal, because growth trajectories of most animals are very similar, but a unified mechanistic theory of growth remains elusive. Still needed is a synthetic explanation for how and why growth rates vary as body size changes, both within individuals over their ontogeny and between populations and species over their evolution. Here, we use Bertalanffy growth equations to characterize growth of ray-finned fishes in terms of two parameters, the growth rate coefficient, K, and final body mass, m∞. We derive two alternative empirically testable hypotheses and test them by analyzing data from FishBase. Across 576 species, which vary in size at maturity by almost nine orders of magnitude, K scaled as [Formula: see text]. This supports our first hypothesis that growth rate scales as [Formula: see text] as predicted by metabolic scaling theory; it implies that species that grow to larger mature sizes grow faster as juveniles. Within fish species, however, K scaled as [Formula: see text]. This supports our second hypothesis, which predicts that growth rate scales as [Formula: see text] when all juveniles grow at the same rate. The unexpected disparity between across- and within-species scaling challenges existing theoretical interpretations. We suggest that the similar ontogenetic programs of closely related populations constrain growth to [Formula: see text] scaling, but as species diverge over evolutionary time they evolve the near-optimal [Formula: see text] scaling predicted by metabolic scaling theory. Our findings have important practical implications because fish supply essential protein in human diets, and sustainable yields from wild harvests and aquaculture depend on growth rates.

A multi-scale tensor voting approach for small retinal vessel segmentation in high resolution fundus images.

PubMed

Christodoulidis, Argyrios; Hurtut, Thomas; Tahar, Houssem Ben; Cheriet, Farida

2016-09-01

Segmenting the retinal vessels from fundus images is a prerequisite for many CAD systems for the automatic detection of diabetic retinopathy lesions. So far, research efforts have concentrated mainly on the accurate localization of the large to medium diameter vessels. However, failure to detect the smallest vessels at the segmentation step can lead to false positive lesion detection counts in a subsequent lesion analysis stage. In this study, a new hybrid method for the segmentation of the smallest vessels is proposed. Line detection and perceptual organization techniques are combined in a multi-scale scheme. Small vessels are reconstructed from the perceptual-based approach via tracking and pixel painting. The segmentation was validated in a high resolution fundus image database including healthy and diabetic subjects using pixel-based as well as perceptual-based measures. The proposed method achieves 85.06% sensitivity rate, while the original multi-scale line detection method achieves 81.06% sensitivity rate for the corresponding images (p<0.05). The improvement in the sensitivity rate for the database is 6.47% when only the smallest vessels are considered (p<0.05). For the perceptual-based measure, the proposed method improves the detection of the vasculature by 7.8% against the original multi-scale line detection method (p<0.05). Copyright © 2016 Elsevier Ltd. All rights reserved.

Comparison of group-based outpatient physiotherapy with usual care after total knee replacement: a feasibility study for a randomized controlled trial.

PubMed

Artz, Neil; Dixon, Samantha; Wylde, Vikki; Marques, Elsa; Beswick, Andrew D; Lenguerrand, Erik; Blom, Ashley W; Gooberman-Hill, Rachael

2017-04-01

To evaluate the feasibility of conducting a randomized controlled trial comparing group-based outpatient physiotherapy with usual care in patients following total knee replacement. A feasibility study for a randomized controlled trial. One secondary-care hospital orthopaedic centre, Bristol, UK. A total of 46 participants undergoing primary total knee replacement. The intervention group were offered six group-based exercise sessions after surgery. The usual care group received standard postoperative care. Participants were not blinded to group allocation. Feasibility was assessed by recruitment, reasons for non-participation, attendance, and completion rates of study questionnaires that included the Lower Extremity Functional Scale and Knee Injury and Osteoarthritis Outcome Score. Recruitment rate was 37%. Five patients withdrew or were no longer eligible to participate. Intervention attendance was high (73%) and 84% of group participants reported they were 'very satisfied' with the exercises. Return of study questionnaires at six months was lower in the usual care (75%) than in the intervention group (100%). Mean (standard deviation) Lower Extremity Functional Scale scores at six months were 45.0 (20.8) in the usual care and 57.8 (15.2) in the intervention groups. Recruitment and retention of participants in this feasibility study was good. Group-based physiotherapy was acceptable to participants. Questionnaire return rates were lower in the usual care group, but might be enhanced by telephone follow-up. The Lower Extremity Functional Scale had high responsiveness and completion rates. Using this outcome measure, 256 participants would be required in a full-scale randomized controlled trial.

Quantitative extraction of the bedrock exposure rate based on unmanned aerial vehicle data and Landsat-8 OLI image in a karst environment

NASA Astrophysics Data System (ADS)

Wang, Hongyan; Li, Qiangzi; Du, Xin; Zhao, Longcai

2017-12-01

In the karst regions of southwest China, rocky desertification is one of the most serious problems in land degradation. The bedrock exposure rate is an important index to assess the degree of rocky desertification in karst regions. Because of the inherent merits of macro-scale, frequency, efficiency, and synthesis, remote sensing is a promising method to monitor and assess karst rocky desertification on a large scale. However, actual measurement of the bedrock exposure rate is difficult and existing remote-sensing methods cannot directly be exploited to extract the bedrock exposure rate owing to the high complexity and heterogeneity of karst environments. Therefore, using unmanned aerial vehicle (UAV) and Landsat-8 Operational Land Imager (OLI) data for Xingren County, Guizhou Province, quantitative extraction of the bedrock exposure rate based on multi-scale remote-sensing data was developed. Firstly, we used an object-oriented method to carry out accurate classification of UAVimages. From the results of rock extraction, the bedrock exposure rate was calculated at the 30 m grid scale. Parts of the calculated samples were used as training data; other data were used for model validation. Secondly, in each grid the band reflectivity of Landsat-8 OLI data was extracted and a variety of rock and vegetation indexes (e.g., NDVI and SAVI) were calculated. Finally, a network model was established to extract the bedrock exposure rate. The correlation coefficient of the network model was 0.855, that of the validation model was 0.677 and the root mean square error of the validation model was 0.073. This method is valuable for wide-scale estimation of bedrock exposure rate in karst environments. Using the quantitative inversion model, a distribution map of the bedrock exposure rate in Xingren County was obtained.

A pilot rating scale for evaluating failure transients in electronic flight control systems

NASA Technical Reports Server (NTRS)

Hindson, William S.; Schroeder, Jeffery A.; Eshow, Michelle M.

1990-01-01

A pilot rating scale was developed to describe the effects of transients in helicopter flight-control systems on safety-of-flight and on pilot recovery action. The scale was applied to the evaluation of hardovers that could potentially occur in the digital flight-control system being designed for a variable-stability UH-60A research helicopter. Tests were conducted in a large moving-base simulator and in flight. The results of the investigation were combined with existing airworthiness criteria to determine quantitative reliability design goals for the control system.

Scaling Factor Variability and Toxicokinetic Outcomes in Children

EPA Science Inventory

Abstract title: Scaling Factor Variability and Toxicokinetic Outcomes in ChildrenBackgroundBiotransformation rates (Vmax) extrapolated from in vitro data are used increasingly in human physiologically based pharmacokinetic (PBPK) models. PBPK models are widely used in human hea...

Large-Scale Hybrid Motor Testing. Chapter 10

NASA Technical Reports Server (NTRS)

Story, George

2006-01-01

Hybrid rocket motors can be successfully demonstrated at a small scale virtually anywhere. There have been many suitcase sized portable test stands assembled for demonstration of hybrids. They show the safety of hybrid rockets to the audiences. These small show motors and small laboratory scale motors can give comparative burn rate data for development of different fuel/oxidizer combinations, however questions that are always asked when hybrids are mentioned for large scale applications are - how do they scale and has it been shown in a large motor? To answer those questions, large scale motor testing is required to verify the hybrid motor at its true size. The necessity to conduct large-scale hybrid rocket motor tests to validate the burn rate from the small motors to application size has been documented in several place^'^^.^. Comparison of small scale hybrid data to that of larger scale data indicates that the fuel burn rate goes down with increasing port size, even with the same oxidizer flux. This trend holds for conventional hybrid motors with forward oxidizer injection and HTPB based fuels. While the reason this is occurring would make a great paper or study or thesis, it is not thoroughly understood at this time. Potential causes include the fact that since hybrid combustion is boundary layer driven, the larger port sizes reduce the interaction (radiation, mixing and heat transfer) from the core region of the port. This chapter focuses on some of the large, prototype sized testing of hybrid motors. The largest motors tested have been AMROC s 250K-lbf thrust motor at Edwards Air Force Base and the Hybrid Propulsion Demonstration Program s 250K-lbf thrust motor at Stennis Space Center. Numerous smaller tests were performed to support the burn rate, stability and scaling concepts that went into the development of those large motors.

Observations on the oxidation of Mn-modified Ni-base Haynes 230 alloy under SOFC exposure conditions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yang, Z Gary; Xia, Gordon; Stevenson, Jeffry W.

2005-07-01

The commercial Ni-base Haynes 230 alloy (Ni-Cr-Mo-W-Mn) was modified with two increased levels of Mn (1 and 2 wt per cent) and evaluated for its oxidation resistance under simulated SOFC interconnect exposure conditions. Oxidation rate, oxide morphology, oxide conductivity and thermal expansion were measured and compared with commercial Haynes 230. It was observed that additions of higher levels of Mn to the bulk alloy facilitated the formation of a bi-layered oxide scale that was comprised of an outer M3O4 (M=Mn, Cr, Ni) spinel-rich layer at the oxide – gas interface over a Cr2O3-rich sub-layer at the metal – oxide interface.more » The modified alloys showed higher oxidation rates and the formation of thicker oxide scales compared to the base alloy. The formation of a spinel-rich top layer improved the scale conductivity, especially during the early stages of the oxidation, but the higher scale growth rate resulted in an increase in the area-specific electrical resistance over time. Due to their face-centered cubic crystal structure, both commercial and modified alloys demonstrated a coefficient of thermal expansion that was higher than that of typical anode-supported and electrolyte-supported SOFCs.« less

Development and pilot testing the Family Conference Rating Scale: A tool aimed to assess interprofessional patient-centred communication and collaboration competencies.

PubMed

Dojeiji, Sue; Byszewski, Anna; Wood, Tim

2015-01-01

There is a paucity of evidence-based literature on the essential communication and collaboration skills to guide health care teams in conducting and assessing their performance in the Family Conference (FC). The authors developed and collected validity evidence for a rating scale of team FC performance, the Family Conference Rating Scale (FCRS). In phase 1, essential FC communication and collaboration skills were identified through a review of existing communication tools and literature on team functioning; a draft 34-item scale was developed. In phase 2, the scale was narrowed to a 6-category, 9-point scale with descriptors of expected behaviours through an iterative process: testing of the scale on 10 FC transcripts by two experts, soliciting feedback from a focus group of seven health care providers, and testing by non-experts on 49 live FCs. In phase 3, scores on the revised scale were validated by 10 health care providers from different disciplines by rating three videos of FCs of variable quality. Raters were able to detect inter-video variation in FC quality. The reliability of the FCRS was 0.95 and the inter-rater reliability, 0.68. The FCRS may enhance the ability of health professions educators to teach and assess interprofessional patient-centred communication and collaboration competencies.

Exploring Rating Quality in Rater-Mediated Assessments Using Mokken Scale Analysis

PubMed Central

Wind, Stefanie A.; Engelhard, George

2015-01-01

Mokken scale analysis is a probabilistic nonparametric approach that offers statistical and graphical tools for evaluating the quality of social science measurement without placing potentially inappropriate restrictions on the structure of a data set. In particular, Mokken scaling provides a useful method for evaluating important measurement properties, such as invariance, in contexts where response processes are not well understood. Because rater-mediated assessments involve complex interactions among many variables, including assessment contexts, student artifacts, rubrics, individual rater characteristics, and others, rater-assigned scores are suitable candidates for Mokken scale analysis. The purposes of this study are to describe a suite of indices that can be used to explore the psychometric quality of data from rater-mediated assessments and to illustrate the substantive interpretation of Mokken-based statistics and displays in this context. Techniques that are commonly used in polytomous applications of Mokken scaling are adapted for use with rater-mediated assessments, with a focus on the substantive interpretation related to individual raters. Overall, the findings suggest that indices of rater monotonicity, rater scalability, and invariant rater ordering based on Mokken scaling provide diagnostic information at the level of individual raters related to the requirements for invariant measurement. These Mokken-based indices serve as an additional suite of diagnostic tools for exploring the quality of data from rater-mediated assessments that can supplement rating quality indices based on parametric models. PMID:29795883

Track-based event recognition in a realistic crowded environment

NASA Astrophysics Data System (ADS)

van Huis, Jasper R.; Bouma, Henri; Baan, Jan; Burghouts, Gertjan J.; Eendebak, Pieter T.; den Hollander, Richard J. M.; Dijk, Judith; van Rest, Jeroen H.

2014-10-01

Automatic detection of abnormal behavior in CCTV cameras is important to improve the security in crowded environments, such as shopping malls, airports and railway stations. This behavior can be characterized at different time scales, e.g., by small-scale subtle and obvious actions or by large-scale walking patterns and interactions between people. For example, pickpocketing can be recognized by the actual snatch (small scale), when he follows the victim, or when he interacts with an accomplice before and after the incident (longer time scale). This paper focusses on event recognition by detecting large-scale track-based patterns. Our event recognition method consists of several steps: pedestrian detection, object tracking, track-based feature computation and rule-based event classification. In the experiment, we focused on single track actions (walk, run, loiter, stop, turn) and track interactions (pass, meet, merge, split). The experiment includes a controlled setup, where 10 actors perform these actions. The method is also applied to all tracks that are generated in a crowded shopping mall in a selected time frame. The results show that most of the actions can be detected reliably (on average 90%) at a low false positive rate (1.1%), and that the interactions obtain lower detection rates (70% at 0.3% FP). This method may become one of the components that assists operators to find threatening behavior and enrich the selection of videos that are to be observed.

Validity and Reliability of the Verbal Numerical Rating Scale for Children Aged 4 to 17 Years With Acute Pain.

PubMed

Tsze, Daniel S; von Baeyer, Carl L; Pahalyants, Vartan; Dayan, Peter S

2018-06-01

The Verbal Numerical Rating Scale is the most commonly used self-report measure of pain intensity. It is unclear how the validity and reliability of the scale scores vary across children's ages. We aimed to determine the validity and reliability of the scale for children presenting to the emergency department across a comprehensive spectrum of age. This was a cross-sectional study of children aged 4 to 17 years. Children self-reported their pain intensity, using the Verbal Numerical Rating Scale and Faces Pain Scale-Revised at 2 serial assessments. We evaluated convergent validity (strong validity defined as correlation coefficient ≥0.60), agreement (difference between concurrent Verbal Numerical Rating Scale and Faces Pain Scale-Revised scores), known-groups validity (difference in score between children with painful versus nonpainful conditions), responsivity (decrease in score after analgesic administration), and reliability (test-retest at 2 serial assessments) in the total sample and subgroups based on age. We enrolled 760 children; 27 did not understand the Verbal Numerical Rating Scale and were removed. Of the remainder, Pearson correlations were strong to very strong (0.62 to 0.96) in all years of age except 4 and 5 years, and agreement was strong for children aged 8 and older. Known-groups validity and responsivity were strong in all years of age. Reliability was strong in all age subgroups, including each year of age from 4 to 7 years. Convergent validity, known-groups validity, responsivity, and reliability of the Verbal Numerical Rating Scale were strong for children aged 6 to 17 years. Convergent validity was not strong for children aged 4 and 5 years. Our findings support the use of the Verbal Numerical Rating Scale for most children aged 6 years and older, but not for those aged 4 and 5 years. Copyright © 2017 American College of Emergency Physicians. Published by Elsevier Inc. All rights reserved.

Scale-up bioprocess development for production of the antibiotic valinomycin in Escherichia coli based on consistent fed-batch cultivations.

PubMed

Li, Jian; Jaitzig, Jennifer; Lu, Ping; Süssmuth, Roderich D; Neubauer, Peter

2015-06-12

Heterologous production of natural products in Escherichia coli has emerged as an attractive strategy to obtain molecules of interest. Although technically feasible most of them are still constrained to laboratory scale production. Therefore, it is necessary to develop reasonable scale-up strategies for bioprocesses aiming at the overproduction of targeted natural products under industrial scale conditions. To this end, we used the production of the antibiotic valinomycin in E. coli as a model system for scalable bioprocess development based on consistent fed-batch cultivations. In this work, the glucose limited fed-batch strategy based on pure mineral salt medium was used throughout all scales for valinomycin production. The optimal glucose feed rate was initially detected by the use of a biocatalytically controlled glucose release (EnBase® technology) in parallel cultivations in 24-well plates with continuous monitoring of pH and dissolved oxygen. These results were confirmed in shake flasks, where the accumulation of valinomycin was highest when the specific growth rate decreased below 0.1 h(-1). This correlation was also observed for high cell density fed-batch cultivations in a lab-scale bioreactor. The bioreactor fermentation produced valinomycin with titers of more than 2 mg L(-1) based on the feeding of a concentrated glucose solution. Valinomycin production was not affected by oscillating conditions (i.e. glucose and oxygen) in a scale-down two-compartment reactor, which could mimic similar situations in industrial bioreactors, suggesting that the process is very robust and a scaling of the process to a larger industrial scale appears a realistic scenario. Valinomycin production was scaled up from mL volumes to 10 L with consistent use of the fed-batch technology. This work presents a robust and reliable approach for scalable bioprocess development and represents an example for the consistent development of a process for a heterologously expressed natural product towards the industrial scale.

Using Cognitive Pretesting in Scale Development for Parkinson’s Disease: The Movement Disorder Society Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) Example

PubMed Central

Tilley, Barbara C.; LaPelle, Nancy R.; Goetz, Christopher G.; Stebbins, Glenn T.

2016-01-01

Background Cognitive pretesting, a qualitative step in scale development, precedes field testing and assesses the difficulty of instrument completion for examiners and respondents. Cognitive pretesting assesses respondent interest, attention span, discomfort, and comprehension, and highlights problems with the logical structure of questions/response options that can affect understanding. In the past this approach was not consistently used in the development or revision of movement disorders scales. Methods We applied qualitative cognitive pretesting using testing guides in development of the Movement Disorder Society-sponsored revision of the Unified Parkinson’s Disease Rating Scale (MDS-UPDRS). The guides were based on qualitative techniques, verbal probing and “think-aloud” interviewing, to identify problems with the scale from the patient and rater perspectives. English-speaking Parkinson’s disease patients and movement disorders specialists (raters) from multiple specialty clinics in the United States, Western Europe and Canada used the MDS-UPDRS and completed the testing guides. Results Two rounds of cognitive pretesting were necessary before proceeding to field testing of the revised scale to assess clinimetric properties. Scale revisions based on cognitive pretesting included changes in phrasing, simplification of some questions, and addition of a reassuring statement explaining that not all PD patients experience the symptoms described in the questions. Conclusions The strategy of incorporating cognitive pretesting into scale development and revision provides a model for other movement disorders scales. Cognitive pretesting is being used in translating the MDS-UPDRS into multiple languages to improve comprehension and acceptance and in the development of a new Unified Dyskinesia Rating Scale for Parkinson’s disease patients. PMID:24613868

Allometric scaling law in a simple oxygen exchanging network: possible implications on the biological allometric scaling laws.

PubMed

Santillán, Moisés

2003-07-21

A simple model of an oxygen exchanging network is presented and studied. This network's task is to transfer a given oxygen rate from a source to an oxygen consuming system. It consists of a pipeline, that interconnects the oxygen consuming system and the reservoir and of a fluid, the active oxygen transporting element, moving through the pipeline. The network optimal design (total pipeline surface) and dynamics (volumetric flow of the oxygen transporting fluid), which minimize the energy rate expended in moving the fluid, are calculated in terms of the oxygen exchange rate, the pipeline length, and the pipeline cross-section. After the oxygen exchanging network is optimized, the energy converting system is shown to satisfy a 3/4-like allometric scaling law, based upon the assumption that its performance regime is scale invariant as well as on some feasible geometric scaling assumptions. Finally, the possible implications of this result on the allometric scaling properties observed elsewhere in living beings are discussed.

Scale factor measure method without turntable for angular rate gyroscope

NASA Astrophysics Data System (ADS)

Qi, Fangyi; Han, Xuefei; Yao, Yanqing; Xiong, Yuting; Huang, Yuqiong; Wang, Hua

2018-03-01

In this paper, a scale factor test method without turntable is originally designed for the angular rate gyroscope. A test system which consists of test device, data acquisition circuit and data processing software based on Labview platform is designed. Taking advantage of gyroscope's sensitivity of angular rate, a gyroscope with known scale factor, serves as a standard gyroscope. The standard gyroscope is installed on the test device together with a measured gyroscope. By shaking the test device around its edge which is parallel to the input axis of gyroscope, the scale factor of the measured gyroscope can be obtained in real time by the data processing software. This test method is fast. It helps test system miniaturized, easy to carry or move. Measure quarts MEMS gyroscope's scale factor multi-times by this method, the difference is less than 0.2%. Compare with testing by turntable, the scale factor difference is less than 1%. The accuracy and repeatability of the test system seems good.

Basic Competence of Intensive Care Unit Nurses: Cross-Sectional Survey Study

PubMed Central

Lakanmaa, Riitta-Liisa; Suominen, Tarja; Ritmala-Castrén, Marita; Vahlberg, Tero; Leino-Kilpi, Helena

2015-01-01

Critical care patients benefit from the attention of nursing personnel with a high competence level. The aim of the study was to describe and evaluate the self-assessed basic competence of intensive care unit nurses and related factors. A cross-sectional survey design was used. A basic competence scale (Intensive and Critical Care Nursing Competence Scale version 1, Likert scale 1–5, 1 = poor and 5 = excellent) was employed among Finnish intensive care unit nurses (n = 431). Intensive care unit nurses' self-assessed basic competence was good (mean 4.19, SD 0.40). The attitude and value base of basic competence was excellent whereas experience base was the poorest compared to the knowledge base and skill base of intensive and critical care nursing. The strongest factor explaining nurses' basic competence was their experience of autonomy in nursing care (F value 60.85, β 0.11, SE 0.01, and P ≤ 0.0001). Clinical competence was self-rated as good. Nurses gave their highest competence self-ratings for ICU patient care according to the principles of nursing care. The ICU nurses also self-rated their professional competence as good. Collaboration was self-rated as the best competence. In basic and continuing education and professional self-development discussions it is meaningful to consider and find solutions for how to improve nurses' experienced autonomy in nursing. PMID:26557676

The impact of variation in scaling factors on the estimation of internal dose metrics: a case study using bromodichloromethane (BDCM)

EPA Science Inventory

Many physiologically based pharmacokinetic (PBPK) models include values for metabolic rate parameters extrapolated from in vitro metabolism studies using scaling factors such as mg of microsomal protein per gram of liver (MPPGL) and liver mass (FVL). Variation in scaling factor ...

The relationship between professional behaviour grades and tutor performance ratings in problem-based learning.

PubMed

Dolmans, Diana Hjm; Luijk, Scheltus J; Wolfhagen, Ineke Hap; Scherpbier, Albert Jja

2006-02-01

We investigated the influence of harsh grading by tutors on tutor performance rating by students. A total of 187 tutors assessed students' professional behaviour in tutorial groups. Students rated tutor performance after receiving their grades for professional behaviour. In addition, students were asked to indicate whether they perceived their professional behaviour grades as too positive, adequate or too negative. This was considered to reflect tutors' harshness of grading. Students also rated the quality of the feedback they received from tutors with respect to their grades. Professional behaviour grades that students perceived as too negative, adequate or too positive were associated with tutor performance ratings of 7.4 (SD = 0.9, scale 1-10, n = 33), 7.7 (SD = 0.9, scale 1-10, n = 95) and 7.5 (SD = 0.8, scale 1-10, n = 59), respectively. Harshness of grading did not influence tutor performance ratings significantly. Tutor ratings were predicted more effectively by the quality of the feedback tutors provided on grades than by the harshness of grading. Tutor performance ratings were not related significantly to harshness of grading. Two explanations can be given: (1) tutor performance ratings were based on rating by groups of students and (2) the percentage of tutors who rated students' professional behaviour as unsatisfactory was low. The strong relationship between tutor performance ratings and the adequacy of the feedback given by tutors suggests that the tutor performance ratings collected in this study are a valid measure of the quality of their teaching, although, for a full picture of teaching quality, more measures will be needed.

Heart rate detection from an electronic weighing scale.

PubMed

González-Landaeta, R; Casas, O; Pallàs-Areny, R

2008-08-01

We propose a novel technique for beat-to-beat heart rate detection based on the ballistocardiographic (BCG) force signal from a subject standing on a common electronic weighing scale. The detection relies on sensing force variations related to the blood acceleration in the aorta, works even if wearing footwear and does not require any sensors attached to the body because it uses the load cells in the scale. We have devised an approach to estimate the sensitivity and frequency response of three commercial weighing scales to assess their capability to detect the BCG force signal. Static sensitivities ranged from 490 nV V(-1) N(-1) to 1670 nV V(-1) N(-1). The frequency response depended on the subject's mass but it was broad enough for heart rate estimation. We have designed an electronic pulse detection system based on off-the-shelf integrated circuits to sense heart-beat-related force variations of about 0.24 N. The signal-to-noise ratio of the main peaks of the force signal detected was higher than 30 dB. A Bland-Altman plot was used to compare the RR time intervals estimated from the ECG and BCG force signals for 17 volunteers. The error was +/-21 ms, which makes the proposed technique suitable for short-term monitoring of the heart rate.

Quantifying Risk of Financial Incapacity and Financial Exploitation in Community-dwelling Older Adults: Utility of a Scoring System for the Lichtenberg Financial Decision-making Rating Scale.

PubMed

Lichtenberg, Peter A; Gross, Evan; Ficker, Lisa J

2018-06-08

This work examines the clinical utility of the scoring system for the Lichtenberg Financial Decision-making Rating Scale (LFDRS) and its usefulness for decision making capacity and financial exploitation. Objective 1 was to examine the clinical utility of a person centered, empirically supported, financial decision making scale. Objective 2 was to determine whether the risk-scoring system created for this rating scale is sufficiently accurate for the use of cutoff scores in cases of decisional capacity and cases of suspected financial exploitation. Objective 3 was to examine whether cognitive decline and decisional impairment predicted suspected financial exploitation. Two hundred independently living, non-demented community-dwelling older adults comprised the sample. Participants completed the rating scale and other cognitive measures. Receiver operating characteristic curves were in the good to excellent range for decisional capacity scoring, and in the fair to good range for financial exploitation. Analyses supported the conceptual link between decision making deficits and risk for exploitation, and supported the use of the risk-scoring system in a community-based population. This study adds to the empirical evidence supporting the use of the rating scale as a clinical tool assessing risk for financial decisional impairment and/or financial exploitation.

The effect of dental scaling noise during intravenous sedation on acoustic respiration rate (RRa™).

PubMed

Kim, Jung Ho; Chi, Seong In; Kim, Hyun Jeong; Seo, Kwang-Suk

2018-04-01

Respiration monitoring is necessary during sedation for dental treatment. Recently, acoustic respiration rate (RRa™), an acoustics-based respiration monitoring method, has been used in addition to auscultation or capnography. The accuracy of this method may be compromised in an environment with excessive noise. This study evaluated whether noise from the ultrasonic scaler affects the performance of RRa in respiratory rate measurement. We analyzed data from 49 volunteers who underwent scaling under intravenous sedation. Clinical tests were divided into preparation, sedation, and scaling periods; respiratory rate was measured at 2-s intervals for 3 min in each period. Missing values ratios of the RRa during each period were measuerd; correlation analysis and Bland-Altman analysis were performed on respiratory rates measured by RRa and capnogram. Respective missing values ratio from RRa were 5.62%, 8.03%, and 23.95% in the preparation, sedation, and scaling periods, indicating an increased missing values ratio in the scaling period (P < 0.001). Correlation coefficients of the respiratory rate, measured with two different methods, were 0.692, 0.677, and 0.562 in each respective period. Mean capnography-RRa biases in Bland-Altman analyses were -0.03, -0.27, and -0.61 in each respective period (P < 0.001); limits of agreement were -4.84-4.45, -4.89-4.15, and -6.18-4.95 (P < 0.001). The probability of missing respiratory rate values was higher during scaling when RRa was used for measurement. Therefore, the use of RRa alone for respiration monitoring during ultrasonic scaling may not be safe.

Uncovering Predictors of Disagreement: Ensuring the Quality of Expert Ratings

ERIC Educational Resources Information Center

Hoth, Jessica; Schwarz, Björn; Kaiser, Gabriele; Busse, Andreas; König, Johannes; Blömeke, Sigrid

2016-01-01

Rating scales are a popular item format used in many types of assessments. Yet, defining which rating is correct often represents a challenge. Using expert ratings as benchmarks is one approach to ensuring the quality of a rating instrument. In this paper, such expert ratings are analyzed in detail taking a video-based test instrument of teachers'…

Effect of long-term interactive music therapy on behavior profile and musical skills in young adults with severe autism.

PubMed

Boso, Marianna; Emanuele, Enzo; Minazzi, Vera; Abbamonte, Marta; Politi, Pierluigi

2007-09-01

Data on the potential behavioral effects of music therapy in autism are scarce. The aim of this study was to investigate whether a musical training program based on interactive music therapy sessions could enhance the behavioral profile and the musical skills of young adults affected by severe autism. Young adults (N = 8) with severe (Childhood Autism Rating Scale >30) autism took part in a total of 52 weekly active music therapy sessions lasting 60 minutes. Each session consisted of a wide range of different musical activities including singing, piano playing, and drumming. Clinical rating scales included the Clinical Global Impression (CGI) scale and the Brief Psychiatric Rating Scale (BPRS). Musical skills-including singing a short or long melody, playing the C scale on a keyboard, music absorption, rhythm reproduction, and execution of complex rhythmic patterns-were rated on a 5-point Likert-type scale ranging from "completely/entirely absent" to "completely/entirely present." At the end of the 52-week training period, significant improvements were found on both the CGI and BPRS scales. Similarly, the patients' musical skills significantly ameliorated as compared to baseline ratings. Our pilot data seem to suggest that active music therapy sessions could be of aid in improving autistic symptoms, as well as personal musical skills in young adults with severe autism.

Seasonal-Scale Dating of a Shallow Ice Core From Greenland Using Oxygen Isotope Matching Between Data and Simulation

NASA Astrophysics Data System (ADS)

Furukawa, Ryoto; Uemura, Ryu; Fujita, Koji; Sjolte, Jesper; Yoshimura, Kei; Matoba, Sumito; Iizuka, Yoshinori

2017-10-01

A precise age scale based on annual layer counting is essential for investigating past environmental changes from ice core records. However, subannual scale dating is hampered by the irregular intraannual variabilities of oxygen isotope (δ18O) records. Here we propose a dating method based on matching the δ18O variations between ice core records and records simulated by isotope-enabled climate models. We applied this method to a new δ18O record from an ice core obtained from a dome site in southeast Greenland. The close similarity between the δ18O records from the ice core and models enables correlation and the production of a precise age scale, with an accuracy of a few months. A missing δ18O minimum in the 1995/1996 winter is an example of an indistinct δ18O seasonal cycle. Our analysis suggests that the missing δ18O minimum is likely caused by a combination of warm air temperature, weak moisture transport, and cool ocean temperature. Based on the age scale, the average accumulation rate from 1960 to 2014 is reconstructed as 1.02 m yr-1 in water equivalent. The annual accumulation rate shows an increasing trend with a slope of 3.6 mm yr-1, which is mainly caused by the increase in the autumn accumulation rate of 2.6 mm yr-1. This increase is likely linked to the enhanced hydrological cycle caused by the decrease in Arctic sea ice area. Unlike the strong seasonality of precipitation amount in the ERA reanalysis data in the southeast dome region, our reconstructed accumulation rate suggests a weak seasonality.

Scaling of coupled dilatancy-diffusion processes in space and time

NASA Astrophysics Data System (ADS)

Main, I. G.; Bell, A. F.; Meredith, P. G.; Brantut, N.; Heap, M.

2012-04-01

Coupled dilatancy-diffusion processes resulting from microscopically brittle damage due to precursory cracking have been observed in the laboratory and suggested as a mechanism for earthquake precursors. One reason precursors have proven elusive may be the scaling in space: recent geodetic and seismic data placing strong limits on the spatial extent of the nucleation zone for recent earthquakes. Another may be the scaling in time: recent laboratory results on axi-symmetric samples show both a systematic decrease in circumferential extensional strain at failure and a delayed and a sharper acceleration of acoustic emission event rate as strain rate is decreased. Here we examine the scaling of such processes in time from laboratory to field conditions using brittle creep (constant stress loading) to failure tests, in an attempt to bridge part of the strain rate gap to natural conditions, and discuss the implications for forecasting the failure time. Dilatancy rate is strongly correlated to strain rate, and decreases to zero in the steady-rate creep phase at strain rates around 10-9 s-1 for a basalt from Mount Etna. The data are well described by a creep model based on the linear superposition of transient (decelerating) and accelerating micro-crack growth due to stress corrosion. The model produces good fits to the failure time in retrospect using the accelerating acoustic emission event rate, but in prospective tests on synthetic data with the same properties we find failure-time forecasting is subject to systematic epistemic and aleatory uncertainties that degrade predictability. The next stage is to use the technology developed to attempt failure forecasting in real time, using live streamed data and a public web-based portal to quantify the prospective forecast quality under such controlled laboratory conditions.

[Spatial-temporal and environmental effects of catch rate on Antarctic krill fishery in the South Georgia Island in the austral winter season based on the fine scale data].

PubMed

Zhu Guo-Ping; Liu, Zi-Jun; Xu, Guo-Dong; Zhang, Ji-Chang; Meng, Tao; Huang, Hong-Liang; Xu, Yi-Ying; Zhu, Xiao-Yan; Xu, Liu-Xiong

2014-08-01

The waters around the South Georgia Island is one of the main fishing ground of Antarctic krill fishery and many predators such as sea seal and whale inhabited this island target Antarctic krill as a food source. So it is very important for further understanding Antarctic ecosystem to conduct the research on abundance fluctuation of Antarctic krill resource around this island. Consequently, based on the fine scale fishery data collected in the winter 2013, using the generalized additive model (GAM), the present study analyzed the relationship between environmental factors and the catch rate of Antarctic krill. The results showed the model could explain 32.0% of the accumulation of deviance of the catch rate. The variable that provided the maximum contribution was ten-day with a contribution rate of 21.4% and followed by the latitude (4.4%). Generally, the catch rate decreased from the first 10 days of July to September. Higher catch rates occurred in the eastern fishing ground, particularly the central-eastern part of survey area, and lower catch rates presented in the northern part. The mean catch rate deceased with the increasing change rate of bathymetry. The oceanographic condition with wind scale below 4 was suitable for fishing operation and associated with the higher catch rate, but the wind direction did not significantly affect the catch rate. The mean catch rate increased with the increasing sea surface temperature within 0.5 to 2.0 degrees C.

Monitoring survival rates of Swainson's Thrush Catharus ustulatus at multiple spatial scales

USGS Publications Warehouse

Rosenberg, D.K.; DeSante, D.F.; McKelvey, K.S.; Hines, J.E.

1999-01-01

We estimated survival rates of Swainson's Thrush, a common, neotropical, migratory landbird, at multiple spatial scales, using data collected in the western USA from the Monitoring Avian Productivity and Survivorship Programme. We evaluated statistical power to detect spatially heterogeneous survival rates and exponentially declining survival rates among spatial scales with simulated populations parameterized from results of the Swainson's Thrush analyses. Models describing survival rates as constant across large spatial scales did not fit the data. The model we chose as most appropriate to describe survival rates of Swainson's Thrush allowed survival rates to vary among Physiographic Provinces, included a separate parameter for the probability that a newly captured bird is a resident individual in the study population, and constrained capture probability to be constant across all stations. Estimated annual survival rates under this model varied from 0.42 to 0.75 among Provinces. The coefficient of variation of survival estimates ranged from 5.8 to 20% among Physiographic Provinces. Statistical power to detect exponentially declining trends was fairly low for small spatial scales, although large annual declines (3% of previous year's rate) were likely to be detected when monitoring was conducted for long periods of time (e.g. 20 years). Although our simulations and field results are based on only four years of data from a limited number and distribution of stations, it is likely that they illustrate genuine difficulties inherent to broadscale efforts to monitor survival rates of territorial landbirds. In particular, our results suggest that more attention needs to be paid to sampling schemes of monitoring programmes, particularly regarding the trade-off between precision and potential bias of parameter estimates at varying spatial scales.

Monitoring survival rates of Swainson's Thrush Catharus ustulatus at multiple spatial scales

USGS Publications Warehouse

Rosenberg, D.K.; DeSante, D.F.; McKelvey, K.S.; Hines, J.E.

1999-01-01

We estimated survival rates of Swainson's Thrush, a common, neotropical, migratory landbird, at multiple spatial scales, using data collected in the western USA from the Monitoring Avian Productivity and Survivorship Programme. We evaluated statistical power to detect spatially heterogeneous survival rates and exponentially declining survival rates among spatial scales with simulated populations parameterized from results of the Swainson's Thrush analyses. Models describing survival rates as constant across large spatial scales did not fit the data. The model we chose as most appropriate to describe survival rates of Swainson's Thrush allowed survival rates to vary among Physiographic Provinces, included a separate parameter for the probability that a newly captured bird is a resident individual in the study population, and constrained capture probability to be constant across all stations. Estimated annual survival rates under this model varied from 0.42 to 0.75 among Provinces. The coefficient of variation of survival estimates ranged from 5.8 to 20% among Physiographic Provinces. Statistical power to detect exponentially declining trends was fairly low for small spatial scales, although large annual declines (3% of previous year's rate) were likely to be detected when monitoring was conducted for long periods of time (e.g. 20 years). Although our simulations and field results are based on only four years of date from a limited number and distribution of stations, it is likely that they illustrate genuine difficulties inherent to broadscale efforts to monitor survival rates of territorial landbirds. In particular, our results suggest that more attention needs to be paid to sampling schemes of monitoring programmes particularly regarding the trade-off between precison and potential bias o parameter estimates at varying spatial scales.

Fundamental insights into ontogenetic growth from theory and fish

PubMed Central

Sibly, Richard M.; Baker, Joanna; Grady, John M.; Luna, Susan M.; Kodric-Brown, Astrid; Venditti, Chris; Brown, James H.

2015-01-01

The fundamental features of growth may be universal, because growth trajectories of most animals are very similar, but a unified mechanistic theory of growth remains elusive. Still needed is a synthetic explanation for how and why growth rates vary as body size changes, both within individuals over their ontogeny and between populations and species over their evolution. Here, we use Bertalanffy growth equations to characterize growth of ray-finned fishes in terms of two parameters, the growth rate coefficient, K, and final body mass, m∞. We derive two alternative empirically testable hypotheses and test them by analyzing data from FishBase. Across 576 species, which vary in size at maturity by almost nine orders of magnitude, K scaled as m∞−0.23. This supports our first hypothesis that growth rate scales as m∞−0.25 as predicted by metabolic scaling theory; it implies that species that grow to larger mature sizes grow faster as juveniles. Within fish species, however, K scaled as m∞−0.35. This supports our second hypothesis, which predicts that growth rate scales as m∞−0.33 when all juveniles grow at the same rate. The unexpected disparity between across- and within-species scaling challenges existing theoretical interpretations. We suggest that the similar ontogenetic programs of closely related populations constrain growth to m∞−0.33 scaling, but as species diverge over evolutionary time they evolve the near-optimal m∞−0.25 scaling predicted by metabolic scaling theory. Our findings have important practical implications because fish supply essential protein in human diets, and sustainable yields from wild harvests and aquaculture depend on growth rates. PMID:26508641

Experimental investigation of fuel regression rate in a HTPB based lab-scale hybrid rocket motor

NASA Astrophysics Data System (ADS)

Li, Xintian; Tian, Hui; Yu, Nanjia; Cai, Guobiao

2014-12-01

The fuel regression rate is an important parameter in the design process of the hybrid rocket motor. Additives in the solid fuel may have influences on the fuel regression rate, which will affect the internal ballistics of the motor. A series of firing experiments have been conducted on lab-scale hybrid rocket motors with 98% hydrogen peroxide (H2O2) oxidizer and hydroxyl terminated polybutadiene (HTPB) based fuels in this paper. An innovative fuel regression rate analysis method is established to diminish the errors caused by start and tailing stages in a short time firing test. The effects of the metal Mg, Al, aromatic hydrocarbon anthracene (C14H10), and carbon black (C) on the fuel regression rate are investigated. The fuel regression rate formulas of different fuel components are fitted according to the experiment data. The results indicate that the influence of C14H10 on the fuel regression rate of HTPB is not evident. However, the metal additives in the HTPB fuel can increase the fuel regression rate significantly.

Complexity Measures, Task Type, and Analytic Evaluations of Speaking Proficiency in a School-Based Assessment Context

ERIC Educational Resources Information Center

Gan, Zhengdong

2012-01-01

This study, which is part of a large-scale study of using objective measures to validate assessment rating scales and assessment tasks in a high-profile school-based assessment initiative in Hong Kong, examined how grammatical complexity measures relate to task type and analytic evaluations of students' speaking proficiency in a classroom-based…

Divided-evolution-based pulse scheme for quantifying exchange processes in proteins: powerful complement to relaxation dispersion experiments.

PubMed

Bouvignies, Guillaume; Hansen, D Flemming; Vallurupalli, Pramodh; Kay, Lewis E

2011-02-16

A method for quantifying millisecond time scale exchange in proteins is presented based on scaling the rate of chemical exchange using a 2D (15)N, (1)H(N) experiment in which (15)N dwell times are separated by short spin-echo pulse trains. Unlike the popular Carr-Purcell-Meiboom-Gill (CPMG) experiment where the effects of a radio frequency field on measured transverse relaxation rates are quantified, the new approach measures peak positions in spectra that shift as the effective exchange time regime is varied. The utility of the method is established through an analysis of data recorded on an exchanging protein-ligand system for which the exchange parameters have been accurately determined using alternative approaches. Computations establish that a combined analysis of CPMG and peak shift profiles extends the time scale that can be studied to include exchanging systems with highly skewed populations and exchange rates as slow as 20 s(-1).

Computer-based attention training in the schools for children with attention deficit/hyperactivity disorder: a preliminary trial.

PubMed

Steiner, Naomi J; Sheldrick, Radley Christopher; Gotthelf, David; Perrin, Ellen C

2011-07-01

Objective. This study examined the efficacy of 2 computer-based training systems to teach children with attention deficit/hyperactivity disorder (ADHD) to attend more effectively. Design/methods. A total of 41 children with ADHD from 2 middle schools were randomly assigned to receive 2 sessions a week at school of either neurofeedback (NF) or attention training through a standard computer format (SCF), either immediately or after a 6-month wait (waitlist control group). Parents, children, and teachers completed questionnaires pre- and postintervention. Results. Primary parents in the NF condition reported significant (P < .05) change on Conners's Rating Scales-Revised (CRS-R) and Behavior Assessment Scales for Children (BASC) subscales; and in the SCF condition, they reported significant (P < .05) change on the CRS-R Inattention scale and ADHD index, the BASC Attention Problems Scale, and on the Behavioral Rating Inventory of Executive Functioning (BRIEF). Conclusion. This randomized control trial provides preliminary evidence of the effectiveness of computer-based interventions for ADHD and supports the feasibility of offering them in a school setting.

Integration of Continuous-Time Dynamics in a Spiking Neural Network Simulator.

PubMed

Hahne, Jan; Dahmen, David; Schuecker, Jannis; Frommer, Andreas; Bolten, Matthias; Helias, Moritz; Diesmann, Markus

2017-01-01

Contemporary modeling approaches to the dynamics of neural networks include two important classes of models: biologically grounded spiking neuron models and functionally inspired rate-based units. We present a unified simulation framework that supports the combination of the two for multi-scale modeling, enables the quantitative validation of mean-field approaches by spiking network simulations, and provides an increase in reliability by usage of the same simulation code and the same network model specifications for both model classes. While most spiking simulations rely on the communication of discrete events, rate models require time-continuous interactions between neurons. Exploiting the conceptual similarity to the inclusion of gap junctions in spiking network simulations, we arrive at a reference implementation of instantaneous and delayed interactions between rate-based models in a spiking network simulator. The separation of rate dynamics from the general connection and communication infrastructure ensures flexibility of the framework. In addition to the standard implementation we present an iterative approach based on waveform-relaxation techniques to reduce communication and increase performance for large-scale simulations of rate-based models with instantaneous interactions. Finally we demonstrate the broad applicability of the framework by considering various examples from the literature, ranging from random networks to neural-field models. The study provides the prerequisite for interactions between rate-based and spiking models in a joint simulation.

Integration of Continuous-Time Dynamics in a Spiking Neural Network Simulator

PubMed Central

Hahne, Jan; Dahmen, David; Schuecker, Jannis; Frommer, Andreas; Bolten, Matthias; Helias, Moritz; Diesmann, Markus

2017-01-01

Contemporary modeling approaches to the dynamics of neural networks include two important classes of models: biologically grounded spiking neuron models and functionally inspired rate-based units. We present a unified simulation framework that supports the combination of the two for multi-scale modeling, enables the quantitative validation of mean-field approaches by spiking network simulations, and provides an increase in reliability by usage of the same simulation code and the same network model specifications for both model classes. While most spiking simulations rely on the communication of discrete events, rate models require time-continuous interactions between neurons. Exploiting the conceptual similarity to the inclusion of gap junctions in spiking network simulations, we arrive at a reference implementation of instantaneous and delayed interactions between rate-based models in a spiking network simulator. The separation of rate dynamics from the general connection and communication infrastructure ensures flexibility of the framework. In addition to the standard implementation we present an iterative approach based on waveform-relaxation techniques to reduce communication and increase performance for large-scale simulations of rate-based models with instantaneous interactions. Finally we demonstrate the broad applicability of the framework by considering various examples from the literature, ranging from random networks to neural-field models. The study provides the prerequisite for interactions between rate-based and spiking models in a joint simulation. PMID:28596730

Grain-Size Based Additivity Models for Scaling Multi-rate Uranyl Surface Complexation in Subsurface Sediments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Xiaoying; Liu, Chongxuan; Hu, Bill X.

This study statistically analyzed a grain-size based additivity model that has been proposed to scale reaction rates and parameters from laboratory to field. The additivity model assumed that reaction properties in a sediment including surface area, reactive site concentration, reaction rate, and extent can be predicted from field-scale grain size distribution by linearly adding reaction properties for individual grain size fractions. This study focused on the statistical analysis of the additivity model with respect to reaction rate constants using multi-rate uranyl (U(VI)) surface complexation reactions in a contaminated sediment as an example. Experimental data of rate-limited U(VI) desorption in amore » stirred flow-cell reactor were used to estimate the statistical properties of multi-rate parameters for individual grain size fractions. The statistical properties of the rate constants for the individual grain size fractions were then used to analyze the statistical properties of the additivity model to predict rate-limited U(VI) desorption in the composite sediment, and to evaluate the relative importance of individual grain size fractions to the overall U(VI) desorption. The result indicated that the additivity model provided a good prediction of the U(VI) desorption in the composite sediment. However, the rate constants were not directly scalable using the additivity model, and U(VI) desorption in individual grain size fractions have to be simulated in order to apply the additivity model. An approximate additivity model for directly scaling rate constants was subsequently proposed and evaluated. The result found that the approximate model provided a good prediction of the experimental results within statistical uncertainty. This study also found that a gravel size fraction (2-8mm), which is often ignored in modeling U(VI) sorption and desorption, is statistically significant to the U(VI) desorption in the sediment.« less

Measuring leader perceptions of school readiness for reforms: use of an iterative model combining classical and Rasch methods.

PubMed

Chatterji, Madhabi

2002-01-01

This study examines validity of data generated by the School Readiness for Reforms: Leader Questionnaire (SRR-LQ) using an iterative procedure that combines classical and Rasch rating scale analysis. Following content-validation and pilot-testing, principal axis factor extraction and promax rotation of factors yielded a five factor structure consistent with the content-validated subscales of the original instrument. Factors were identified based on inspection of pattern and structure coefficients. The rotated factor pattern, inter-factor correlations, convergent validity coefficients, and Cronbach's alpha reliability estimates supported the hypothesized construct properties. To further examine unidimensionality and efficacy of the rating scale structures, item-level data from each factor-defined subscale were subjected to analysis with the Rasch rating scale model. Data-to-model fit statistics and separation reliability for items and persons met acceptable criteria. Rating scale results suggested consistency of expected and observed step difficulties in rating categories, and correspondence of step calibrations with increases in the underlying variables. The combined approach yielded more comprehensive diagnostic information on the quality of the five SRR-LQ subscales; further research is continuing.

A Theoretical Basis for Entropy-Scaling Effects in Human Mobility Patterns.

PubMed

Osgood, Nathaniel D; Paul, Tuhin; Stanley, Kevin G; Qian, Weicheng

2016-01-01

Characterizing how people move through space has been an important component of many disciplines. With the advent of automated data collection through GPS and other location sensing systems, researchers have the opportunity to examine human mobility at spatio-temporal resolution heretofore impossible. However, the copious and complex data collected through these logging systems can be difficult for humans to fully exploit, leading many researchers to propose novel metrics for encapsulating movement patterns in succinct and useful ways. A particularly salient proposed metric is the mobility entropy rate of the string representing the sequence of locations visited by an individual. However, mobility entropy rate is not scale invariant: entropy rate calculations based on measurements of the same trajectory at varying spatial or temporal granularity do not yield the same value, limiting the utility of mobility entropy rate as a metric by confounding inter-experimental comparisons. In this paper, we derive a scaling relationship for mobility entropy rate of non-repeating straight line paths from the definition of Lempel-Ziv compression. We show that the resulting formulation predicts the scaling behavior of simulated mobility traces, and provides an upper bound on mobility entropy rate under certain assumptions. We further show that this formulation has a maximum value for a particular sampling rate, implying that optimal sampling rates for particular movement patterns exist.

Measuring Functional Creativity: Non-Expert Raters and the Creative Solution Diagnosis Scale

ERIC Educational Resources Information Center

Cropley, David H.; Kaufman, James C.

2012-01-01

The Creative Solution Diagnosis Scale (CSDS) is a 30-item scale based on a core of four criteria: Relevance & Effectiveness, Novelty, Elegance, and Genesis. The CSDS offers potential for the consensual assessment of functional product creativity. This article describes an empirical study in which non-expert judges rated a series of mousetrap…

The Relationship Between the Childhood Autism Rating Scale: Second Edition and Clinical Diagnosis Utilizing the DSM-IV-TR and the DSM-5.

PubMed

Dawkins, Tamara; Meyer, Allison T; Van Bourgondien, Mary E

2016-10-01

The Childhood Autism Rating Scale, Second Edition (CARS2; 2010) includes two rating scales; the CARS2-Standard Version (CARS2-ST) and the newly developed CARS2-High Functioning Version (CARS2-HF). To assess the diagnostic agreement between the CARS2 and DSM-IV-TR versus DSM-5 criteria for Autism Spectrum Disorder (ASD), clinicians at community based centers of the University of North Carolina TEACCH Autism Program rated participants seen for a diagnostic evaluation on symptoms of autism using both the DSM-IV-TR and DSM-5 criteria and either the CARS2-HF or the CARS2-ST. Findings suggest that overall, the diagnostic agreement of the CARS2 remains high across DSM-IV and DSM-5 criteria for autism.

Early reading performance: a comparison of teacher-based and test-based assessments.

PubMed

Kenny, D T; Chekaluk, E

1993-04-01

An unresolved question in early screening is whether test-based or teacher-based assessments should form the basis of the classification of children at risk of educational failure. Available structured teacher rating scales are lacking in predictive validity, and teacher predictions of students likely to experience reading difficulties have yielded disappointing true positive rates, with teachers failing to identify the majority of severely disabled readers. For this study, three educational screening instruments were developed: (a) a single teacher rating, categorizing children into three levels of reading ability (advanced, average, poor); (b) a 15-item teacher questionnaire designed to measure students' cognitive and language ability, attentional and behavioral characteristics, and academic performance; and (c) a battery of language and reading tests that are predictive of, or correlate with, reading failure. The concurrent validity of each instrument was assessed in a sample of 312 Australian schoolchildren from kindergarten, Year 1, and Year 2. Students were assessed at the end of the 1989 school year after having completed 1, 2, or 3 years of schooling. The results suggest that the nature of the skills required for success in reading changes in the first 3 years of schooling. Both teachers and tests concur more closely as children progress through the elementary years and as the risk behavior (reading) becomes more accessible to direct measurement. Carefully focused teacher rating scales may be a cost-effective means of identifying children at risk of reading failure. Improved teacher rating scales should be developed and used to assist in the early screening process.

BMP4 density gradient in disk-shaped confinement

NASA Astrophysics Data System (ADS)

Bozorgui, Behnaz; Teimouri, Hamid; Kolomeisky, Anatoly B.

We present a quantitative model that explains the scaling of BMP4 gradients during gastrulation and the recent experimental observation that geometric confinement of human embryonic stem cells is sufficient to recapitulate much of germ layer patterning. Based on a assumption that BMP4 diffusion rate is much smaller than the diffusion rate of it's inhibitor molecules, our results confirm that the length-scale which defines germ layer territories does not depend on system size.

Development of multiscale complexity and multifractality of fetal heart rate variability.

PubMed

Gierałtowski, Jan; Hoyer, Dirk; Tetschke, Florian; Nowack, Samuel; Schneider, Uwe; Zebrowski, Jan

2013-11-01

During fetal development a complex system grows and coordination over multiple time scales is formed towards an integrated behavior of the organism. Since essential cardiovascular and associated coordination is mediated by the autonomic nervous system (ANS) and the ANS activity is reflected in recordable heart rate patterns, multiscale heart rate analysis is a tool predestined for the diagnosis of prenatal maturation. The analyses over multiple time scales requires sufficiently long data sets while the recordings of fetal heart rate as well as the behavioral states studied are themselves short. Care must be taken that the analysis methods used are appropriate for short data lengths. We investigated multiscale entropy and multifractal scaling exponents from 30 minute recordings of 27 normal fetuses, aged between 23 and 38 weeks of gestational age (WGA) during the quiet state. In multiscale entropy, we found complexity lower than that of non-correlated white noise over all 20 coarse graining time scales investigated. Significant maturation age related complexity increase was strongest expressed at scale 2, both using sample entropy and generalized mutual information as complexity estimates. Multiscale multifractal analysis (MMA) in which the Hurst surface h(q,s) is calculated, where q is the multifractal parameter and s is the scale, was applied to the fetal heart rate data. MMA is a method derived from detrended fluctuation analysis (DFA). We modified the base algorithm of MMA to be applicable for short time series analysis using overlapping data windows and a reduction of the scale range. We looked for such q and s for which the Hurst exponent h(q,s) is most correlated with gestational age. We used this value of the Hurst exponent to predict the gestational age based only on fetal heart rate variability properties. Comparison with the true age of the fetus gave satisfying results (error 2.17±3.29 weeks; p<0.001; R(2)=0.52). In addition, we found that the normally used DFA scale range is non-optimal for fetal age evaluation. We conclude that 30 min recordings are appropriate and sufficient for assessing fetal age by multiscale entropy and multiscale multifractal analysis. The predominant prognostic role of scale 2 heart beats for MSE and scale 39 heart beats (at q=-0.7) for MMA cannot be explored neither by single scale complexity measures nor by standard detrended fluctuation analysis. Copyright © 2013 Elsevier B.V. All rights reserved.

Ontogenetic scaling of metabolism, growth, and assimilation: testing metabolic scaling theory with Manduca sexta larvae.

PubMed

Sears, Katie E; Kerkhoff, Andrew J; Messerman, Arianne; Itagaki, Haruhiko

2012-01-01

Metabolism, growth, and the assimilation of energy and materials are essential processes that are intricately related and depend heavily on animal size. However, models that relate the ontogenetic scaling of energy assimilation and metabolism to growth rely on assumptions that have yet to be rigorously tested. Based on detailed daily measurements of metabolism, growth, and assimilation in tobacco hornworms, Manduca sexta, we provide a first experimental test of the core assumptions of a metabolic scaling model of ontogenetic growth. Metabolic scaling parameters changed over development, in violation of the model assumptions. At the same time, the scaling of growth rate matches that of metabolic rate, with similar scaling exponents both across and within developmental instars. Rates of assimilation were much higher than expected during the first two instars and did not match the patterns of scaling of growth and metabolism, which suggests high costs of biosynthesis early in development. The rapid increase in size and discrete instars observed in larval insect development provide an ideal system for understanding how patterns of growth and metabolism emerge from fundamental cellular processes and the exchange of materials and energy between an organism and its environment.

Education-Stratified Base-Rate Information on Discrepancy Scores Within and Between the Wechsler Adult Intelligence Scale-Third Edition and the Wechsler Memory Scale-Third Edition

ERIC Educational Resources Information Center

Dori, Galit A.; Chelune, Gordon J.

2004-01-01

The Wechsler Adult Intelligence Scale--Third Edition (WAIS-III; D. Wechsler, 1997a) and the Wechsler Memory Scale--Third Edition (WMS-III; D. Wechsler, 1997b) are 2 of the most frequently used measures in psychology and neuropsychology. To facilitate the diagnostic use of these measures in the clinical decision-making process, this article…

Effects on centre-based training and home-based training on physical function, quality of life and fall incidence in community dwelling older adults.

PubMed

Kwok, Thomas M K; Tong, C Y

2014-05-01

This was a quasi-experimental study to compare the effects of center-based training with home-based training on physical function, quality of life and fall incidence in older adults. Fifty older adults were recruited to receive exercise training for 6 months. Participants in the center-based group received training under supervision of a physiotherapist at the day training center. Those in the home-based group received training assisted by a care worker at home. The outcome measures were the Elderly Mobility Scale (EMS), Berg Balance Scale (BBS), Numeric Pain Rating Scale (NPRS), Short-form 12 (SF-12) and fall incidence. Assessments were performed on all participants before and after the 6-month intervention period. Center-based training supervised by a physiotherapist was found to have beneficial effects on physical function, quality of life and fall incidence while home-based training assisted by a care worker had no effect on physical condition and self-rated health status in community dwelling older adults. Service agents should provide center-based or home-based training to the ageing population in a user-friendly way with consideration of factors such as rehabilitation potential and accessibility of transportation.

Quantitative 4D Transcatheter Intraarterial Perfusion MR Imaging as a Method to Standardize Angiographic Chemoembolization Endpoints

PubMed Central

Jin, Brian; Wang, Dingxin; Lewandowski, Robert J.; Ryu, Robert K.; Sato, Kent T.; Larson, Andrew C.; Salem, Riad; Omary, Reed A.

2011-01-01

PURPOSE We aimed to test the hypothesis that subjective angiographic endpoints during transarterial chemoembolization (TACE) of hepatocellular carcinoma (HCC) exhibit consistency and correlate with objective intraprocedural reductions in tumor perfusion as determined by quantitative four dimensional (4D) transcatheter intraarterial perfusion (TRIP) magnetic resonance (MR) imaging. MATERIALS AND METHODS This prospective study was approved by the institutional review board. Eighteen consecutive patients underwent TACE in a combined MR/interventional radiology (MR-IR) suite. Three board-certified interventional radiologists independently graded the angiographic endpoint of each procedure based on a previously described subjective angiographic chemoembolization endpoint (SACE) scale. A consensus SACE rating was established for each patient. Patients underwent quantitative 4D TRIP-MR imaging immediately before and after TACE, from which mean whole tumor perfusion (Fρ) was calculated. Consistency of SACE ratings between observers was evaluated using the intraclass correlation coefficient (ICC). The relationship between SACE ratings and intraprocedural TRIP-MR imaging perfusion changes was evaluated using Spearman’s rank correlation coefficient. RESULTS The SACE rating scale demonstrated very good consistency among all observers (ICC = 0.80). The consensus SACE rating was significantly correlated with both absolute (r = 0.54, P = 0.022) and percent (r = 0.85, P < 0.001) intraprocedural perfusion reduction. CONCLUSION The SACE rating scale demonstrates very good consistency between raters, and significantly correlates with objectively measured intraprocedural perfusion reductions during TACE. These results support the use of the SACE scale as a standardized alternative method to quantitative 4D TRIP-MR imaging to classify patients based on embolic endpoints of TACE. PMID:22021520

Effect of Alloying Additions on Oxidation Behaviors of Ni-Fe Based Superalloy for Ultra-Supercritical Boiler Applications

NASA Astrophysics Data System (ADS)

Lu, Jintao; Yang, Zhen; Zhao, Xinbao; Yan, Jingbo; Gu, Y.

A new kind of Ni-Fe-based superalloy is designed recently for 750 °C-class A-USC boiler tube. The oxidation behavior of the designed alloys with various combinations of anti-oxidation additions, Cr, Al and Si, was investigated at 750 °C and 850 °C, respectively. The results indicated that the oxidation rate of tested alloys decreased with the increase of the sum of additions. Cr addition may drop the relative constant of parabolic rate greatly when temperature is raised. But the oxide scale, mainly consisted of NiCr spinel at 750 °C and NiCrMn spinel at 850 °C, was similar while the Cr content is in a range of 20-25 wt.% at tested temperatures. Al addition, however, showed the best effective to reduce the oxidation rates. Internal Al-rich oxide was observed at the scale/metal interface for alloys added with high content of Al and was increased with Al content increase. Very tiny difference between the oxide scales of the Si-added alloys was identified when Si content varies among 0.02-0.05 wt.%. Basing on these results, this presentation discussed the optimum combination of anti-oxidation additions as well as oxidation mechanisms in the designed Ni-Fe-base superalloy.

Development and Validation of the Social, Academic, and Emotional Behavior Risk Screener-Student Rating Scale

ERIC Educational Resources Information Center

von der Embse, Nathaniel P.; Iaccarino, Stephanie; Mankin, Ariel; Kilgus, Stephen P.; Magen, Eran

2017-01-01

School systems are the primary providers for the increasing number of children with mental health needs. School-based universal screening offers a valuable way to identify children that would benefit from school-based mental health services. However, many existing screening systems rely on teacher ratings alone and do not incorporate student…

Log-polar mapping-based scale space tracking with adaptive target response

NASA Astrophysics Data System (ADS)

Li, Dongdong; Wen, Gongjian; Kuai, Yangliu; Zhang, Ximing

2017-05-01

Correlation filter-based tracking has exhibited impressive robustness and accuracy in recent years. Standard correlation filter-based trackers are restricted to translation estimation and equipped with fixed target response. These trackers produce an inferior performance when encountered with a significant scale variation or appearance change. We propose a log-polar mapping-based scale space tracker with an adaptive target response. This tracker transforms the scale variation of the target in the Cartesian space into a shift along the logarithmic axis in the log-polar space. A one-dimensional scale correlation filter is learned online to estimate the shift along the logarithmic axis. With the log-polar representation, scale estimation is achieved accurately without a multiresolution pyramid. To achieve an adaptive target response, a variance of the Gaussian function is computed from the response map and updated online with a learning rate parameter. Our log-polar mapping-based scale correlation filter and adaptive target response can be combined with any correlation filter-based trackers. In addition, the scale correlation filter can be extended to a two-dimensional correlation filter to achieve joint estimation of the scale variation and in-plane rotation. Experiments performed on an OTB50 benchmark demonstrate that our tracker achieves superior performance against state-of-the-art trackers.

[Rating scales based on the phenomenological and structural approach].

PubMed

Schiltz, L

2006-01-01

A current tendency of research in clinical psychology consists in using an integrated quantitative and qualitative methodology. This approach is especially suited to the study of the therapeutic intervention where the researcher is himself part of the situation he is investigating. As to the tools of research, the combination of the semi-structured clinical interview, of psychometric scales and projective tests has proved to be pertinent to describe the multidimensional and fluctuating reality of the therapeutic relationship and the changes induced by it in the two partners. In arts therapeutic research the investigation of the artistic production or of the free expression of people may complete the psychometric and projective tools. The concept of "expressive test" is currently being used to characterise this method. In this context, the development of rating scales, based on the phenomenological and structural or holistic approach allows us making the link between qualitative analysis and quantification, leading to the use of inferential statistics, providing that we remain at the nominal or ordinal level of measurement. We are explaining the principle of construction of these rating scales and we are illustrating our practice with some examples drawn from studies we realized in clinical psychology.

An improved feature extraction algorithm based on KAZE for multi-spectral image

NASA Astrophysics Data System (ADS)

Yang, Jianping; Li, Jun

2018-02-01

Multi-spectral image contains abundant spectral information, which is widely used in all fields like resource exploration, meteorological observation and modern military. Image preprocessing, such as image feature extraction and matching, is indispensable while dealing with multi-spectral remote sensing image. Although the feature matching algorithm based on linear scale such as SIFT and SURF performs strong on robustness, the local accuracy cannot be guaranteed. Therefore, this paper proposes an improved KAZE algorithm, which is based on nonlinear scale, to raise the number of feature and to enhance the matching rate by using the adjusted-cosine vector. The experiment result shows that the number of feature and the matching rate of the improved KAZE are remarkably than the original KAZE algorithm.

Assessment of Competence in EVAR Procedures: A Novel Rating Scale Developed by the Delphi Technique.

PubMed

Strøm, M; Lönn, L; Bech, B; Schroeder, T V; Konge, L

2017-07-01

To develop a procedure specific global rating scale for assessment of operator competence in endovascular aortic repair (EVAR). A Delphi approach was used to achieve expert consensus. A panel of 32 international experts (median 300 EVAR procedures, range 200-3000) from vascular surgery (n = 21) and radiology (n = 11) was established. The first Delphi round was based on a review of endovascular skills assessment papers, stent graft instructions for use, and structured interviews. It led to a primary pool of 83 items that were formulated as global rating scale items with tentative anchors. Iterative Delphi rounds were executed. The panellists rated the importance of each item on a 5 point Likert scale. Consensus was defined as 80% of the panel rating an item 4 or 5 in the primary round and 90% in subsequent rounds. Consensus on the final assessment tool was defined as Cronbach's alpha > .8 after a minimum of three rounds. Thirty-two of 35 invited experts participated. Three rounds of surveys were completed with a completion rate of 100% in the first two rounds and 91% in round three. The 83 primary assessment items were supplemented with five items suggested by the panel and reduced to seven pivotal assessment items that reached consensus, Cronbach's alpha = 0.82. The seven item rating scale covers key elements of competence in EVAR stent placement and deployment. Each item has well defined grades with explicit anchors at unacceptable, acceptable, and superior performance on a 5 point Likert scale. The Delphi methodology allowed for international consensus on a new procedure specific global rating scale for assessment of competence in EVAR. The resulting scale, EndoVascular Aortic Repair Assessment of Technical Expertise (EVARATE), represents key elements in the procedure. EVARATE constitutes an assessment tool for providing structured feedback to endovascular operators in training. Copyright © 2017 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.

Characterizing and modelling river channel migration rates at a regional scale: Case study of south-east France.

PubMed

Alber, Adrien; Piégay, Hervé

2017-11-01

An increased awareness by river managers of the importance of river channel migration to sediment dynamics, habitat complexity and other ecosystem functions has led to an advance in the science and practice of identifying, protecting or restoring specific erodible corridors across which rivers are free to migrate. One current challenge is the application of these watershed-specific goals at the regional planning scales (e.g., the European Water Framework Directive). This study provides a GIS-based spatial analysis of the channel migration rates at the regional-scale. As a case study, 99 reaches were sampled in the French part of the Rhône Basin and nearby tributaries of the Mediterranean Sea (111,300 km 2 ). We explored the spatial correlation between the channel migration rate and a set of simple variables (e.g., watershed area, channel slope, stream power, active channel width). We found that the spatial variability of the channel migration rates was primary explained by the gross stream power (R 2  = 0.48) and more surprisingly by the active channel width scaled by the watershed area. The relationship between the absolute migration rate and the gross stream power is generally consistent with the published empirical models for freely meandering rivers, whereas it is less significant for the multi-thread reaches. The discussion focused on methodological constraints for a regional-scale modelling of the migration rates, and the interpretation of the empirical models. We hypothesize that the active channel width scaled by the watershed area is a surrogate for the sediment supply which may be a more critical factor than the bank resistance for explaining the regional-scale variability of the migration rates. Copyright © 2016 Elsevier Ltd. All rights reserved.

Characterizing regional-scale temporal evolution of air dose rates after the Fukushima Daiichi Nuclear Power Plant accident.

PubMed

Wainwright, Haruko M; Seki, Akiyuki; Mikami, Satoshi; Saito, Kimiaki

2018-09-01

In this study, we quantify the temporal changes of air dose rates in the regional scale around the Fukushima Dai-ichi Nuclear Power Plant in Japan, and predict the spatial distribution of air dose rates in the future. We first apply the Bayesian geostatistical method developed by Wainwright et al. (2017) to integrate multiscale datasets including ground-based walk and car surveys, and airborne surveys, all of which have different scales, resolutions, spatial coverage, and accuracy. This method is based on geostatistics to represent spatial heterogeneous structures, and also on Bayesian hierarchical models to integrate multiscale, multi-type datasets in a consistent manner. We apply this method to the datasets from three years: 2014 to 2016. The temporal changes among the three integrated maps enables us to characterize the spatiotemporal dynamics of radiation air dose rates. The data-driven ecological decay model is then coupled with the integrated map to predict future dose rates. Results show that the air dose rates are decreasing consistently across the region. While slower in the forested region, the decrease is particularly significant in the town area. The decontamination has contributed to significant reduction of air dose rates. By 2026, the air dose rates will continue to decrease, and the area above 3.8 μSv/h will be almost fully contained within the non-residential forested zone. Copyright © 2018 Elsevier Ltd. All rights reserved.

Effectiveness of symptom validity measures in identifying cognitive and behavioral symptom exaggeration in adult attention deficit hyperactivity disorder.

PubMed

Marshall, Paul; Schroeder, Ryan; O'Brien, Jeffrey; Fischer, Rebecca; Ries, Adam; Blesi, Brita; Barker, Jessica

2010-10-01

This study examines the effectiveness of symptom validity measures to detect suspect effort in cognitive testing and invalid completion of ADHD behavior rating scales in 268 adults referred for ADHD assessment. Patients were diagnosed with ADHD based on cognitive testing, behavior rating scales, and clinical interview. Suspect effort was diagnosed by at least two of the following: failure on embedded and free-standing SVT measures, a score > 2 SD below the ADD population average on tests, failure on an ADHD behavior rating scale validity scale, or a major discrepancy between reported and observed ADHD behaviors. A total of 22% of patients engaged in symptom exaggeration. The Word Memory test immediate recall and consistency score (both 64%), TOVA omission errors (63%) and reaction time variability (54%), CAT-A infrequency scale (58%), and b Test (47%) had good sensitivity as well as at least 90% specificity. Clearly, such measures should be used to help avoid making false positive diagnoses of ADHD.

Comparison of isothermal and cyclic oxidation behavior of twenty-five commercial sheet alloys at 1150 C

NASA Technical Reports Server (NTRS)

Barrett, C. A.; Lowell, C. E.

1974-01-01

The cyclic and isothermal oxidation resistance of 25 high-temperature Ni-, Co-, and Fe-base sheet alloys after 100 hours in air at 1150 C was compared. The alloys were evaluated in terms of their oxidation, scaling, and vaporization rates and their tendency for scale spallation. These values were used to develop an oxidation rating parameter based on effective thickness change, as calculated from a mass balance. The calculated thicknesses generally agreed with the measured values, including grain boundary oxidation, to within a factor of 3. Oxidation behavior was related to composition, particularly Cr and Al content.

Problems with the dating of sediment core using excess (210)Pb in a freshwater system impacted by large scale watershed changes.

PubMed

Baskaran, Mark; Nix, Joe; Kuyper, Clark; Karunakara, N

2014-12-01

Pb-210 dating of freshwater and coastal sediments have been extensively conducted over the past 40 years for historical pollution reconstruction studies, sediment focusing, sediment accumulation and mixing rate determination. In areas where there is large scale disturbance of sediments and the watershed, the vertical profiles of excess (210)Pb ((210)Pbxs) could provide erroneous or less reliable information on sediment accumulation rates. We analyzed one sediment core from Hendrix Lake in southwestern Arkansas for excess (210)Pb and (137)Cs. There is no decrease in excess (210)Pb activity with depth while the (137)Cs profile indicates sharp peak corresponding to 1963 and the (137)Cs penetration depth of (137)Cs corresponds to 1952. The historical data on the accelerated mercury mining during 1931-1944 resulted in large-scale Hg input to this watershed. Using the peak Hg activity as a time marker, the obtained sediment accumulation rates agree well with the (137)Cs-based rates. Four independent evidences (two-marker events based on (137)Cs and two marker events based on Hg mining activity) result in about the same sedimentation rates and thus, we endorse earlier suggestion that (210)Pb profile always needs to be validated with at least one another independent method. We also present a concise discussion on what important factors that can affect the vertical profiles of (210)Pbxs in relatively smaller lakes. Copyright © 2014 Elsevier Ltd. All rights reserved.

AirSTAR: A UAV Platform for Flight Dynamics and Control System Testing

NASA Technical Reports Server (NTRS)

Jordan, Thomas L.; Foster, John V.; Bailey, Roger M.; Belcastro, Christine M.

2006-01-01

As part of the NASA Aviation Safety Program at Langley Research Center, a dynamically scaled unmanned aerial vehicle (UAV) and associated ground based control system are being developed to investigate dynamics modeling and control of large transport vehicles in upset conditions. The UAV is a 5.5% (seven foot wingspan), twin turbine, generic transport aircraft with a sophisticated instrumentation and telemetry package. A ground based, real-time control system is located inside an operations vehicle for the research pilot and associated support personnel. The telemetry system supports over 70 channels of data plus video for the downlink and 30 channels for the control uplink. Data rates are in excess of 200 Hz. Dynamic scaling of the UAV, which includes dimensional, weight, inertial, actuation, and control system scaling, is required so that the sub-scale vehicle will realistically simulate the flight characteristics of the full-scale aircraft. This testbed will be utilized to validate modeling methods, flight dynamics characteristics, and control system designs for large transport aircraft, with the end goal being the development of technologies to reduce the fatal accident rate due to loss-of-control.

Multidisciplinary Delphi Development of a Scale to Evaluate Team Function in Obstetric Emergencies: The PETRA Scale.

PubMed

Balki, Mrinalini; Hoppe, David; Monks, David; Cooke, Mary Ellen; Sharples, Lynn; Windrim, Rory

2017-06-01

The objective of this study was to develop a new interdisciplinary teamwork scale, the Perinatal Emergency: Team Response Assessment (PETRA), for the management of obstetric crises, through consensus agreement of obstetric caregivers. This prospective study was performed using expert consensus, based on a Delphi method. The study investigators developed a new PETRA tool, specifically related to obstetric crisis management, based on the existing literature and discussions among themselves. The scale was distributed to a selected panel of experts in the field for the Delphi process. After each round of Delphi, every component of the scale was analyzed quantitatively by the percentage of agreement ratings and each comment reviewed by the blinded investigators. The assessment scale was then modified, with components of less than 80% agreement removed from the scale. The process was repeated on three occasions to reach a consensus and final PETRA scale. Fourteen of 24 invited experts participated in the Delphi process. The original PETRA scale included six categories and 48 items, one global scale item, and a 3-point rubric for rating. The overall percentage agreement by experts in the first, second, and third rounds was 95.0%, 93.2%, and 98.5%, respectively. The final scale after the third round of Delphi consisted of the following seven categories: shared mental model, communication, situational awareness, leadership, followership, workload management, and positive/effective behaviours and attitudes. There were 34 individual items within these categories, each with a 5-point rating rubric (1 = unacceptable to 5 = perfect). Using a structured Delphi method, we established the face and content validity of this assessment scale that focuses on important aspects of interdisciplinary teamwork in the management of obstetric crises. Copyright © 2017 The Society of Obstetricians and Gynaecologists of Canada/La Société des obstétriciens et gynécologues du Canada. Published by Elsevier Inc. All rights reserved.

Study of the influence of the supersaturation coefficient on scaling rate using the pre-calcified surface of a quartz crystal microbalance.

PubMed

Cheap-Charpentier, Hélène; Horner, Olivier; Lédion, Jean; Perrot, Hubert

2018-05-29

Scale deposition is a common issue in industrial plants, which creates technical problems, i.e. reduction of heat transfer, decrease of flow rate due to an obstruction of pipes. Therefore, the development of some appropriate methods based on well suitable in situ sensors to evaluate and predict the scaling propensity of water is a major concern in current research. This would be a good strategy for the optimization of anti-scaling treatments. In this study, scaling tests were carried out using a sensitive sensor, which has been developed using a quartz crystal microbalance with a pre-calcified electrode surface (SQCM). This technique allowed studying the influence of the supersaturation on the scaling rate. The set-up was tested with different water samples which were brought to a given supersaturation coefficient by degassing the dissolved CO 2 . The prediction of the scaling propensity of water was then possible through the relationship between the scaling rate on a pre-calcified surface and the supersaturation coefficient. In addition, the kinetics of CaCO 3 deposit on the pre-calcified SQCM surface was found to be slower for natural water than for synthetic water (same calcium concentration). Furthermore, the activation energy for scale deposit, in synthetic water, was found to be 22 kJ.mol -1 , which may be related to the diffusion of ions and/or CaCO 3 nuclei in solution. Copyright © 2018 Elsevier Ltd. All rights reserved.

Exercise Prescription Using a Group-Normalized Rating of Perceived Exertion in Adolescents and Adults With Spina Bifida.

PubMed

Crytzer, Theresa M; Keramati, Mariam; Anthony, Steven J; Cheng, Yu-Ting; Robertson, Robert J; Dicianno, Brad E

2018-02-03

People with spina bifida (SB) face personal and environmental barriers to exercise that contribute to physical inactivity, obesity, risk of cardiovascular disease, and poor aerobic fitness. The WHEEL rating of perceived exertion (RPE) Scale was validated in people with SB to monitor exercise intensity. However, the psycho-physiological link between RPE and ventilatory breakpoint (Vpt), the group-normalized perceptual response, has not been determined and would provide a starting point for aerobic exercise in this cohort. The primary objectives were to determine the group-normalized RPE equivalent to Vpt based on WHEEL and Borg Scale ratings and to develop a regression model to predict Borg Scale (conditional metric) from WHEEL Scale (criterion metric). The secondary objective was to create a table of interchangeable values between WHEEL and Borg Scale RPE for people with SB performing a load incremental stress test. Cross-sectional observational. University laboratory. Twenty-nine participants with SB. Participants completed a load incremented arm ergometer exercise stress test. WHEEL and Borg Scale ratings were recorded the last 15 seconds of each 1-minute test phase. WHEEL and Borg Scale ratings, metabolic measures (eg, oxygen consumption, carbon dioxide production). Determined Vpt via plots of oxygen consumption and carbon dioxide production against time. Nineteen of 29 participants achieved Vpt (Group A). The mean ± standard deviation peak oxygen consumption at Vpt for Group A was 61.76 ± 16.26. The WHEEL and Borg Scale RPE at Vpt were 5.74 ± 2.58 (range 0-10) and 13.95 ± 3.50 (range 6-19), respectively. A significant linear regression model was developed (Borg Scale rating = 1.22 × WHEEL Scale rating + 7.14) and used to create a WHEEL-to-Borg Scale RPE conversion table. A significant linear regression model and table of interchangeable values was developed for participants with SB. The group-normalized RPE (WHEEL, 5.74; Borg, 13.95) can be used to prescribe and self-regulate arm ergometer exercise intensity approximating the Vpt. II. Copyright © 2018. Published by Elsevier Inc.

On scaling cosmogenic nuclide production rates for altitude and latitude using cosmic-ray measurements

NASA Astrophysics Data System (ADS)

Desilets, Darin; Zreda, Marek

2001-11-01

The wide use of cosmogenic nuclides for dating terrestrial landforms has prompted a renewed interest in characterizing the spatial distribution of terrestrial cosmic rays. Cosmic-ray measurements from neutron monitors, nuclear emulsions and cloud chambers have played an important role in developing new models for scaling cosmic-ray neutron intensities and, indirectly, cosmogenic production rates. Unfortunately, current scaling models overlook or misinterpret many of these data. In this paper, we describe factors that must be considered when using neutron measurements to determine scaling formulations for production rates of cosmogenic nuclides. Over the past 50 years, the overwhelming majority of nucleon flux measurements have been taken with neutron monitors. However, in order to use these data for scaling spallation reactions, the following factors must be considered: (1) sensitivity of instruments to muons and to background, (2) instrumental biases in energy sensitivity, (3) solar activity, and (4) the way of ordering cosmic-ray data in the geomagnetic field. Failure to account for these factors can result in discrepancies of as much as 7% in neutron attenuation lengths measured at the same location. This magnitude of deviation can result in an error on the order of 20% in cosmogenic production rates scaled from 4300 m to sea level. The shapes of latitude curves of nucleon flux also depend on these factors to a measurable extent, thereby causing additional uncertainties in cosmogenic production rates. The corrections proposed herein significantly improve our ability to transfer scaling formulations based on neutron measurements to scaling formulations applicable to spallation reactions, and, therefore, constitute an important advance in cosmogenic dating methodology.

Thermal Catalytic Syngas Cleanup for High-Efficiency Waste-to-Energy Converters

DTIC Science & Technology

2015-12-01

characteristics for a full-scale WEC based on the collected experimental data. 20 RESULTS AND DISCUSSION Task 1 – Tar-Cracking Reactor...prepared to show the effect of reaching the target throughput rate of 50 lb/hr on conversion efficiency. In scaling up the experimental results , the...Midmoisture Full Moisture Fuel Feed Rate, kg/hr 22.3 22.3 22.3 Results Using the Experimental Recuperator Effectiveness Fuel Energy In, kWth 160 136 121

Experimental evidence of rainfall driven knickpoints

NASA Astrophysics Data System (ADS)

Singh, A.; Tejedor, A.; Grimaud, J. L.; Foufoula-Georgiou, E.

2017-12-01

Formation of knickpoints is typically associated with a landscape's response to differential uplift causing a base-level fall that results in a steep region along a river's long profile. However, to the best of our knowledge, knickpoints have never been reported to form in landscapes subject to varying precipitation rate wherein uplift rate remains constant. Here we reveal evidence that knickpoints can indeed result from increasing precipitation rate, which reorganizes the production and delivery of sediment across a range of spatial and temporal scales, creating thus constraints and water-sediment flux disequilibria at local scales. We base our findings on analysis of high resolution topography data obtained from an experimental landscape conducted to study the effect of changing rainfall intensity on landscape evolution at short and long-time scales. Results from our study suggest that at the transient state of increasing precipitation, a scale-dependent behavior of erosion rates emerges that results in a regime shift in the transport processes in channels from supply-limited to sediment-flux dependent. This regime shift is caused by an increase in the sediment supply from the hillslopes, generating variability in water to sediment flux ratio (Qs/Qw) in channels of different sub-drainage basins which is further manifested in the longitudinal river profiles as abrupt changes in their gradients (knickpoints), advecting upstream on the river network as time proceeds.

The incremental validity of a computerised assessment added to clinical rating scales to differentiate adult ADHD from autism spectrum disorder.

PubMed

Groom, Madeleine J; Young, Zoe; Hall, Charlotte L; Gillott, Alinda; Hollis, Chris

2016-09-30

There is a clinical need for objective evidence-based measures that are sensitive and specific to ADHD when compared with other neurodevelopmental disorders. This study evaluated the incremental validity of adding an objective measure of activity and computerised cognitive assessment to clinical rating scales to differentiate adult ADHD from Autism spectrum disorders (ASD). Adults with ADHD (n=33) or ASD (n=25) performed the QbTest, comprising a Continuous Performance Test with motion-tracker to record physical activity. QbTest parameters measuring inattention, impulsivity and hyperactivity were combined to provide a summary score ('QbTotal'). Binary stepwise logistic regression measured the probability of assignment to the ADHD or ASD group based on scores on the Conners Adult ADHD Rating Scale-subscale E (CAARS-E) and Autism Quotient (AQ10) in the first step and then QbTotal added in the second step. The model fit was significant at step 1 (CAARS-E, AQ10) with good group classification accuracy. These predictors were retained and QbTotal was added, resulting in a significant improvement in model fit and group classification accuracy. All predictors were significant. ROC curves indicated superior specificity of QbTotal. The findings present preliminary evidence that adding QbTest to clinical rating scales may improve the differentiation of ADHD and ASD in adults. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

SMALL-SCALE FUEL ALCOHOL PRODUCTION TO MEET UNIVERSITY VEHICLE FUEL NEEDS AND PROMOTE REGIONAL SUSTAINABLE DEVELOPMENT

EPA Science Inventory

1. The small scale sweet sorghum ethanol production system in Iowa has good potential for development based on an economic analysis with rates of return ranging from 12% to 32 % for ethanol prices ranging from $1.66/gal to $2.20/gal. A scale of 300 acres (121 ha) for produ...

2. The Single-Item Math Anxiety Scale: An Alternative Way of Measuring Mathematical Anxiety

   ERIC Educational Resources Information Center

   Núñez-Peña, M. Isabel; Guilera, Georgina; Suárez-Pellicioni, Macarena

   2014-01-01

   This study examined whether the Single-Item Math Anxiety Scale (SIMA), based on the item suggested by Ashcraft, provided valid and reliable scores of mathematical anxiety. A large sample of university students (n = 279) was administered the SIMA and the 25-item Shortened Math Anxiety Rating Scale (sMARS) to evaluate the relation between the scores…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fang, Ming; Albrecht, Bruce A.; Ghate, Virendra P.

This study first illustrates the utility of using the Doppler spectrum width from millimetrewavelength radar to calculate the energy dissipation rate and then to use the energy dissipation rate to study turbulence structure in a continental stratocumulus cloud. It is shown that the turbulence kinetic energy dissipation rate calculated from the radar-measured Doppler spectrum width agrees well with that calculated from the Doppler velocity power spectrum. During the 16-h stratocumulus cloud event, the small-scale turbulence contributes 40%of the total velocity variance at cloud base, 50% at normalized cloud depth=0.8 and 70% at cloud top, which suggests that small-scale turbulence playsmore » a critical role near the cloud top where the entrainment and cloud-top radiative cooling act. The 16-h mean vertical integral length scale decreases from about 160 m at cloud base to 60 m at cloud top, and this signifies that the larger scale turbulence dominates around cloud base whereas the small-scale turbulence dominates around cloud top. The energy dissipation rate, total variance and squared spectrum width exhibit diurnal variations, but unlike marine stratocumulus they are high during the day and lowest around sunset at all levels; energy dissipation rates increase at night with the intensification of the cloud-top cooling. In the normalized coordinate system, the averaged coherent structure of updrafts is characterized by low energy dissipation rates in the updraft core and higher energy dissipation rates surround the updraft core at the top and along the edges. In contrast, the energy dissipation rate is higher inside the downdraft core indicating that the downdraft core is more turbulent. The turbulence around the updraft is weaker at night and stronger during the day; the opposite is true around the downdraft. This behaviour indicates that the turbulence in the downdraft has a diurnal cycle similar to that observed in marine stratocumuluswhereas the turbulence diurnal cycle in the updraft is reversed. For both updraft and downdraft, the maximum energy dissipation rate occurs at a cloud depth=0.8 where the maximum reflectivity and air acceleration or deceleration are observed. Resolved turbulence dominates near cloud base whereas unresolved turbulence dominates near cloud top. Similar to the unresolved turbulence, the resolved turbulence described by the radial velocity variance is higher in the downdraft than in the updraft. The impact of the surface heating on the resolved turbulence in the updraft decreases with height and diminishes around the cloud top. In both updrafts and downdrafts, the resolved turbulence increases with height and reaches a maximum at cloud depth=0.4 and then decreases to the cloud top; the resolved turbulence near cloud top, just as the unresolved turbulence, is mostly due to the cloud-top radiative cooling.« less

Office-based Electromyography-guided Botulinum Toxin Injection to the Cricopharyngeus Muscle: Optimal Patient Selection and Technique.

PubMed

Kim, Min-Su; Kim, Go-Woon; Rho, Young-Soo; Kwon, Kee-Hwan; Chung, Eun-Jae

2017-05-01

This retrospective study was carried out to investigate the effectiveness and safety of office-based electromyography-guided injection of botulinum toxin in the cricopharyngeus muscle of patients who did not show upper esophageal sphincter passage in a swallowing study in spite of maximal swallowing rehabilitation. Thirty-six patients who showed no or limited ability to oral feed after maximum swallowing rehabilitation were enrolled. Video fluoroscopic swallowing study, flexible endoscopic evaluation of swallowing, disability rating scale, penetration aspiration score, and National Institutes of Health swallowing safety scale were used in the evaluation of dysphagia. Success was defined as nondependence on gastrostomy for patients who previously were dependent on gastrostomy and improvement in disability rating scale score after botulinum toxin injections. The total success rate was 63.9%. The complication rate was very low, with only 1 patient showing temporary unilateral vocal fold paralysis. Botulinum toxin injection was more effective in patients with cranial nerve IX or X palsy than in those without it ( P = .006). This procedure can be a simple, safe, and effective tool in patients with cricopharyngeal dysfunction after swallowing rehabilitation, especially for cranial nerve IX or X palsy.

Addressing Angular Single-Event Effects in the Estimation of On-Orbit Error Rates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, David S.; Swift, Gary M.; Wirthlin, Michael J.

2015-12-01

Our study describes complications introduced by angular direct ionization events on space error rate predictions. In particular, prevalence of multiple-cell upsets and a breakdown in the application of effective linear energy transfer in modern-scale devices can skew error rates approximated from currently available estimation models. Moreover, this paper highlights the importance of angular testing and proposes a methodology to extend existing error estimation tools to properly consider angular strikes in modern-scale devices. Finally, these techniques are illustrated with test data provided from a modern 28 nm SRAM-based device.

A scaling transformation for classifier output based on likelihood ratio: Applications to a CAD workstation for diagnosis of breast cancer

PubMed Central

Horsch, Karla; Pesce, Lorenzo L.; Giger, Maryellen L.; Metz, Charles E.; Jiang, Yulei

2012-01-01

Purpose: The authors developed scaling methods that monotonically transform the output of one classifier to the “scale” of another. Such transformations affect the distribution of classifier output while leaving the ROC curve unchanged. In particular, they investigated transformations between radiologists and computer classifiers, with the goal of addressing the problem of comparing and interpreting case-specific values of output from two classifiers. Methods: Using both simulated and radiologists’ rating data of breast imaging cases, the authors investigated a likelihood-ratio-scaling transformation, based on “matching” classifier likelihood ratios. For comparison, three other scaling transformations were investigated that were based on matching classifier true positive fraction, false positive fraction, or cumulative distribution function, respectively. The authors explored modifying the computer output to reflect the scale of the radiologist, as well as modifying the radiologist’s ratings to reflect the scale of the computer. They also evaluated how dataset size affects the transformations. Results: When ROC curves of two classifiers differed substantially, the four transformations were found to be quite different. The likelihood-ratio scaling transformation was found to vary widely from radiologist to radiologist. Similar results were found for the other transformations. Our simulations explored the effect of database sizes on the accuracy of the estimation of our scaling transformations. Conclusions: The likelihood-ratio-scaling transformation that the authors have developed and evaluated was shown to be capable of transforming computer and radiologist outputs to a common scale reliably, thereby allowing the comparison of the computer and radiologist outputs on the basis of a clinically relevant statistic. PMID:22559651

Kinematic segmentation of accretive wedges based on scaled sandbox experiments and their application to nature

NASA Astrophysics Data System (ADS)

Lohrmann, J.; Kukowski, N.; Oncken, O.

2003-04-01

Recording the incremental displacement field of scaled analogue simulations provides detailed data on wedge kinematics and timing of internal deformation. This is a very efficient tool to develop kinematic concepts and test mechanical theories, e.g. the critical-taper theory. Such models could not be validated until now by the available geological and geophysical data, since there was no information about the incremental displacement field. Recent GPS measurements and seismological investigations at convergent margins provide well-constrained strain-rates and kinematics of short-termed processes. These data allow the kinematic models that are based on analogue simulations to be tested against field observations. We investigate convergent accretive sand wedges in scaled analogue simulations. We define three kinematic segments based on distinctive wedge taper, displacement field and timing of deformation (recorded at a slow sampling rate, which represents the geological scale). Only one of these segments is in a critical state of stress, whereas the other segments are either in a sub-critical or stable state of stress. Such a kinematic segmentation is not predicted for ideally homogeneous wedge-shaped bodies by the critical-taper theory, but can be explained by the formation of localised weak shear zones, which preferentially accommodate deformation. These weak zones are formed in granular analogue materials, and also in natural rocks, since these materials show a strain-softening phase prior to the achievement of stable mechanical conditions. Therefore we suggest that the kinematic segmentation of convergent sand wedges should also be observed in natural settings, such as accretionary wedges, foreland fold-and-thrust belts and even entire orogens. To validate this hypothesis we compare strain rates from GPS measurements and kinematics deduced from focal mechanisms with the respective data from sandbox experiments. We present a strategy to compare strain rates and kinematics recorded in nature with kinematic models based on sandbox experiments. In the sandbox experiments we use a fast sampling rate in accordance with GPS measurements. We investigate whether strain rates obtained from the GPS measurements can test mechanical concepts of long-termed geodynamic processes.

A new respirometric endpoint-based biosensor to assess the relative toxicity of chemicals on immobilized human cells.

PubMed

Dragone, Roberto; Frazzoli, Chiara; Grappelli, Claudio; Campanella, Luigi

2009-01-01

Several functional and biochemical parameters have been proposed as biomarkers of effect of environmental pollutants. A rapid biosensor working with immobilized human U-937 cells was developed and applied to environmentally relevant chemicals with different structures and toxicological pathways, i.e. benzalkonium chloride, clofibric acid, diclofenac, mercury nitrate, ofloxacin, and sodium dodecyl sulphate. Respiration of cells was relied upon as a comprehensive biochemical effect for screening purposes. Analytical parameter (DeltappmO(2)) and toxicological index (respiratory inhibition, delta%) measured after 1h of exposure were utilized for dose-response relationship study. Results (toxicity rating scales based on delta(50)% and steepness) were compared with those obtained by the same approach previously optimized on Saccharomyces cerevisiae. The toxicity rating scale obtained by the biomarker based on human mitochondrial and cell metabolic activities compared well with previous scale obtained on yeast cells and with available in-vivo acute toxicity indexes; respiration was confirmed as toxicological endpoint reliably measurable by the biosensor.

Toward topology-based characterization of small-scale mixing in compressible turbulence

NASA Astrophysics Data System (ADS)

Suman, Sawan; Girimaji, Sharath

2011-11-01

Turbulent mixing rate at small scales of motion (molecular mixing) is governed by the steepness of the scalar-gradient field which in turn is dependent upon the prevailing velocity gradients. Thus motivated, we propose a velocity-gradient topology-based approach for characterizing small-scale mixing in compressible turbulence. We define a mixing efficiency metric that is dependent upon the topology of the solenoidal and dilatational deformation rates of a fluid element. The mixing characteristics of solenoidal and dilatational velocity fluctuations are clearly delineated. We validate this new approach by employing mixing data from direct numerical simulations (DNS) of compressible decaying turbulence with passive scalar. For each velocity-gradient topology, we compare the mixing efficiency predicted by the topology-based model with the corresponding conditional scalar variance obtained from DNS. The new mixing metric accurately distinguishes good and poor mixing topologies and indeed reasonably captures the numerical values. The results clearly demonstrate the viability of the proposed approach for characterizing and predicting mixing in compressible flows.

Evaluation of high fidelity patient simulator in assessment of performance of anaesthetists.

PubMed

Weller, J M; Bloch, M; Young, S; Maze, M; Oyesola, S; Wyner, J; Dob, D; Haire, K; Durbridge, J; Walker, T; Newble, D

2003-01-01

There is increasing emphasis on performance-based assessment of clinical competence. The High Fidelity Patient Simulator (HPS) may be useful for assessment of clinical practice in anaesthesia, but needs formal evaluation of validity, reliability, feasibility and effect on learning. We set out to assess the reliability of a global rating scale for scoring simulator performance in crisis management. Using a global rating scale, three judges independently rated videotapes of anaesthetists in simulated crises in the operating theatre. Five anaesthetists then independently rated subsets of these videotapes. There was good agreement between raters for medical management, behavioural attributes and overall performance. Agreement was high for both the initial judges and the five additional raters. Using a global scale to assess simulator performance, we found good inter-rater reliability for scoring performance in a crisis. We estimate that two judges should provide a reliable assessment. High fidelity simulation should be studied further for assessing clinical performance.

Recovery and concordance in a secure forensic psychiatry hospital - the self rated DUNDRUM-3 programme completion and DUNDRUM-4 recovery scales.

PubMed

Davoren, Mary; Hennessy, Sarah; Conway, Catherine; Marrinan, Seamus; Gill, Pauline; Kennedy, Harry G

2015-03-28

Detention in a secure forensic psychiatric hospital may inhibit engagement and recovery. Having validated the clinician rated DUNDRUM-3 (programme completion) and DUNDRUM-4 (recovery) in a forensic hospital, we set out to draft and validate scales measuring the same programme completion and recovery items that patients could use to self-rate. Based on previous work, we hypothesised that self-rating scores might be predictors of objective progress including conditional discharge. We hypothesised also that the difference between patients' and clinicians' ratings of progress in treatment and other factors relevant to readiness for discharge (concordance) would diminish as patients neared discharge. We hypothesised also that this difference in matched scores would predict objective progress including conditional discharge. In a prospective naturalistic observational cohort study in a forensic hospital, we examined whether scores on the self-rated DUNDRUM-3 programme completion and DUNDRUM-4 recovery scales or differences between clinician and patient ratings on the same scales (concordance) would predict moves between levels of therapeutic security and conditional discharge over the next twelve months. Both scales stratified along the recovery pathway of the hospital, but clinician ratings matched the level of therapeutic security more accurately than self ratings. The clinician rated scales predicted moves to less secure units and to more secure units and predicted conditional discharge but the self-rated scores did not. The difference between clinician and self-rated scores (concordance) predicted positive and negative moves and conditional discharge, but this was not always an independent predictor as shown by regression analysis. In regression analysis the DUNDRUM-3 predicted moves to less secure places though the HCR-20 C & R score dominated the model. Moves back to more secure places were predicted by lack of concordance on the DUNDRUM-4. Conditional discharge was predicted predominantly by the DUNDRUM-3. Patients accurately self-rate relative to other patients however their absolute ratings were consistently lower (better) than clinicians' ratings and were less accurate predictors of outcomes including conditional discharge. Quantifying concordance is a useful part of the recovery process and predicts outcomes but self-ratings are not accurate predictors.

COMPARISON OF IN VIVO DERIVED AND SCALED IN VITRO METABOLIC RATE CONSTANTS FOR SOME VOLATILE ORGANIC COMPOUNDS (VOCS)

EPA Science Inventory

The reliability of physiologically based pharmacokinetic (PBPK) models is directly related to the accuracy of the metabolic rate parameters used as model inputs. When metabolic rate parameters derived from in vivo experiments are unavailable, they can be estimated from in vitro d...

Scaling in Free-Swimming Fish and Implications for Measuring Size-at-Time in the Wild

PubMed Central

Broell, Franziska; Taggart, Christopher T.

2015-01-01

This study was motivated by the need to measure size-at-age, and thus growth rate, in fish in the wild. We postulated that this could be achieved using accelerometer tags based first on early isometric scaling models that hypothesize that similar animals should move at the same speed with a stroke frequency that scales with length-1, and second on observations that the speed of primarily air-breathing free-swimming animals, presumably swimming ‘efficiently’, is independent of size, confirming that stroke frequency scales as length-1. However, such scaling relations between size and swimming parameters for fish remain mostly theoretical. Based on free-swimming saithe and sturgeon tagged with accelerometers, we introduce a species-specific scaling relationship between dominant tail beat frequency (TBF) and fork length. Dominant TBF was proportional to length-1 (r2 = 0.73, n = 40), and estimated swimming speed within species was independent of length. Similar scaling relations accrued in relation to body mass-0.29. We demonstrate that the dominant TBF can be used to estimate size-at-time and that accelerometer tags with onboard processing may be able to provide size-at-time estimates among free-swimming fish and thus the estimation of growth rate (change in size-at-time) in the wild. PMID:26673777

The roles of social support in helping chinese women with antenatal depressive and anxiety symptoms cope with perceived stress.

PubMed

Lau, Ying; Wong, Daniel Fu Keung; Wang, Yuqiong; Kwong, Dennis Ho Keung; Wang, Ying

2014-10-01

A community-based sample of 755 pregnant Chinese women were recruited to test the direct and moderating effects of social support in mitigating perceived stress associated with antenatal depressive or anxiety symptoms. The Social Support Rating Scale, the Perceived Stress Scale, the Edinburgh Depressive Postnatal Scale and the Zung Self-Rating Anxiety Scale were used. Social support was found to have direct effects and moderating effects on the women's perceived stress on antenatal depressive and anxiety symptoms in multiple linear regression models. This knowledge of the separate effects of social support on behavioral health is important to psychiatric nurse in planning preventive interventions. Copyright © 2014 Elsevier Inc. All rights reserved.

Computerized Measurement of Negative Symptoms in Schizophrenia

PubMed Central

Cohen, Alex S.; Alpert, Murray; Nienow, Tasha M.; Dinzeo, Thomas J.; Docherty, Nancy M.

2008-01-01

Accurate measurement of negative symptoms is crucial for understanding and treating schizophrenia. However, current measurement strategies are reliant on subjective symptom rating scales which often have psychometric and practical limitations. Computerized analysis of patients’ speech offers a sophisticated and objective means of evaluating negative symptoms. The present study examined the feasibility and validity of using widely-available acoustic and lexical-analytic software to measure flat affect, alogia and anhedonia (via positive emotion). These measures were examined in their relationships to clinically-rated negative symptoms and social functioning. Natural speech samples were collected and analyzed for 14 patients with clinically-rated flat affect, 46 patients without flat affect and 19 healthy controls. The computer-based inflection and speech rate measures significantly discriminated patients with flat affect from controls, and the computer-based measure of alogia and negative emotion significantly discriminated the flat and non-flat patients. Both the computer and clinical measures of positive emotion/anhedonia corresponded to functioning impairments. The computerized method of assessing negative symptoms offered a number of advantages over the symptom scale-based approach. PMID:17920078

A rating system for the esthetics of bridges.

DOT National Transportation Integrated Search

1980-01-01

There is a need for a tangible way to evaluate the esthetic or visual characteristics of bridges. This report describes such a method based on a numerical experiential rating scale of -10 to +10. Negative values represent unpleasurable responses; pos...

Kinetic Modeling of Slow Energy Release in Non-Ideal Carbon Rich Explosives

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vitello, P; Fried, L; Glaesemann, K

2006-06-20

We present here the first self-consistent kinetic based model for long time-scale energy release in detonation waves in the non-ideal explosive LX-17. Non-ideal, insensitive carbon rich explosives, such as those based on TATB, are believed to have significant late-time slow release in energy. One proposed source of this energy is diffusion-limited growth of carbon clusters. In this paper we consider the late-time energy release problem in detonation waves using the thermochemical code CHEETAH linked to a multidimensional ALE hydrodynamics model. The linked CHEETAH-ALE model dimensional treats slowly reacting chemical species using kinetic rate laws, with chemical equilibrium assumed for speciesmore » coupled via fast time-scale reactions. In the model presented here we include separate rate equations for the transformation of the un-reacted explosive to product gases and for the growth of a small particulate form of condensed graphite to a large particulate form. The small particulate graphite is assumed to be in chemical equilibrium with the gaseous species allowing for coupling between the instantaneous thermodynamic state and the production of graphite clusters. For the explosive burn rate a pressure dependent rate law was used. Low pressure freezing of the gas species mass fractions was also included to account for regions where the kinetic coupling rates become longer than the hydrodynamic time-scales. The model rate parameters were calibrated using cylinder and rate-stick experimental data. Excellent long time agreement and size effect results were achieved.« less

Development of the Comprehensive Cervical Dystonia Rating Scale: Methodology

PubMed Central

Comella, Cynthia L.; Fox, Susan H.; Bhatia, Kailash P.; Perlmutter, Joel S.; Jinnah, Hyder A.; Zurowski, Mateusz; McDonald, William M.; Marsh, Laura; Rosen, Ami R.; Waliczek, Tracy; Wright, Laura J.; Galpern, Wendy R.; Stebbins, Glenn T.

2016-01-01

We present the methodology utilized for development and clinimetric testing of the Comprehensive Cervical Dystonia (CD) Rating scale, or CCDRS. The CCDRS includes a revision of the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS-2), a newly developed psychiatric screening tool (TWSTRS-PSYCH), and the previously validated Cervical Dystonia Impact Profile (CDIP-58). For the revision of the TWSTRS, the original TWSTRS was examined by a committee of dystonia experts at a dystonia rating scales workshop organized by the Dystonia Medical Research Foundation. During this workshop, deficiencies in the standard TWSTRS were identified and recommendations for revision of the severity and pain subscales were incorporated into the TWSTRS-2. Given that no scale currently evaluates the psychiatric features of cervical dystonia (CD), we used a modified Delphi methodology and a reiterative process of item selection to develop the TWSTRS-PSYCH. We also included the CDIP-58 to capture the impact of CD on quality of life. The three scales (TWSTRS2, TWSTRS-PSYCH, and CDIP-58) were combined to construct the CCDRS. Clinimetric testing of reliability and validity of the CCDRS are described. The CCDRS was designed to be used in a modular fashion that can measure the full spectrum of CD. This scale will provide rigorous assessment for studies of natural history as well as novel symptom-based or disease-modifying therapies. PMID:27088112

Development of the Comprehensive Cervical Dystonia Rating Scale: Methodology.

PubMed

Comella, Cynthia L; Fox, Susan H; Bhatia, Kailash P; Perlmutter, Joel S; Jinnah, Hyder A; Zurowski, Mateusz; McDonald, William M; Marsh, Laura; Rosen, Ami R; Waliczek, Tracy; Wright, Laura J; Galpern, Wendy R; Stebbins, Glenn T

2015-06-01

We present the methodology utilized for development and clinimetric testing of the Comprehensive Cervical Dystonia (CD) Rating scale, or CCDRS. The CCDRS includes a revision of the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS-2), a newly developed psychiatric screening tool (TWSTRS-PSYCH), and the previously validated Cervical Dystonia Impact Profile (CDIP-58). For the revision of the TWSTRS, the original TWSTRS was examined by a committee of dystonia experts at a dystonia rating scales workshop organized by the Dystonia Medical Research Foundation. During this workshop, deficiencies in the standard TWSTRS were identified and recommendations for revision of the severity and pain subscales were incorporated into the TWSTRS-2. Given that no scale currently evaluates the psychiatric features of cervical dystonia (CD), we used a modified Delphi methodology and a reiterative process of item selection to develop the TWSTRS-PSYCH. We also included the CDIP-58 to capture the impact of CD on quality of life. The three scales (TWSTRS2, TWSTRS-PSYCH, and CDIP-58) were combined to construct the CCDRS. Clinimetric testing of reliability and validity of the CCDRS are described. The CCDRS was designed to be used in a modular fashion that can measure the full spectrum of CD. This scale will provide rigorous assessment for studies of natural history as well as novel symptom-based or disease-modifying therapies.

Combining agreement and frequency rating scales to optimize psychometrics in measuring behavioral health functioning.

PubMed

Marfeo, Elizabeth E; Ni, Pengsheng; Chan, Leighton; Rasch, Elizabeth K; Jette, Alan M

2014-07-01

The goal of this article was to investigate optimal functioning of using frequency vs. agreement rating scales in two subdomains of the newly developed Work Disability Functional Assessment Battery: the Mood & Emotions and Behavioral Control scales. A psychometric study comparing rating scale performance embedded in a cross-sectional survey used for developing a new instrument to measure behavioral health functioning among adults applying for disability benefits in the United States was performed. Within the sample of 1,017 respondents, the range of response category endorsement was similar for both frequency and agreement item types for both scales. There were fewer missing values in the frequency items than the agreement items. Both frequency and agreement items showed acceptable reliability. The frequency items demonstrated optimal effectiveness around the mean ± 1-2 standard deviation score range; the agreement items performed better at the extreme score ranges. Findings suggest an optimal response format requires a mix of both agreement-based and frequency-based items. Frequency items perform better in the normal range of responses, capturing specific behaviors, reactions, or situations that may elicit a specific response. Agreement items do better for those whose scores are more extreme and capture subjective content related to general attitudes, behaviors, or feelings of work-related behavioral health functioning. Copyright © 2014 Elsevier Inc. All rights reserved.

Anthropogenic nitrogen sources and exports in a village-scale catchment in Southeast China.

PubMed

Cao, Wenzhi; Hong, Huasheng; Zhang, Yuzhen; Chen, Nengwang; Zeng, Yue; Wang, Weiping

2006-01-01

An experimental village-scale catchment was selected for investigation of nitrogen (N) sources and exports. The mean N application rate over the catchment was 350.2 kg N ha(-1), but this rate varied spatially and temporally. The N leaching loss rate varied from 8.1 to 52.7 kg N ha(-1) under different land use regimes. The average N leaching loss rate was 13.4 kg N ha(-1) over the whole catchment, representing about 3.8% of the total N inputs. The N export rate through stormflows was 28.8 kg N ha(-1), about 8.2% of the total N inputs. Seasonal patterns showed that 95% of N exports through stormflows occurred during July to September in 2002. Overall, the maximum riverine N exports were 12.1% of total N inputs and 15.5% of the inorganic fertilizer N applied. Understanding N sources and exports in a village-scale catchment can provide a knowledge base for amelioration of diffuse agricultural pollution.

The 0.040-scale space shuttle orbiter base heating model tests in the Lewis Research Center space power facility

NASA Technical Reports Server (NTRS)

Dezelick, R. A.

1976-01-01

Space shuttle base heating tests were conducted using a 0.040-scale model in the Plum Brook Space Power Facility of The NASA Lewis Research Center. The tests measured heat transfer rates, pressure distributions, and gas recovery temperatures on the orbiter vehicle 2A base configuration resulting from engine plume impingement. One hundred and sixty-eight hydrogen-oxygen engine firings were made at simulated flight altitudes ranging from 120,000 to 360,000 feet.

Program director opinions of core competencies in hand surgery training: analysis of differences between plastic and orthopedic surgery accredited programs.

PubMed

Sears, Erika Davis; Larson, Bradley P; Chung, Kevin C

2013-03-01

The authors' aim was to conduct a national survey of hand surgery fellowship program directors to determine differences of opinions of essential components of hand surgery training between program directors from plastic and orthopedic surgery programs. The authors performed a Web-based survey of 74 program directors from all Accreditation Council for Graduate Medical Education-accredited hand surgery fellowship programs to determine components that are essential for hand surgery training. The survey included assessment of nine general areas of practice, 97 knowledge topics, and 172 procedures. Twenty-seven scales of related survey items were created to determine differences between specialty groups based on clinical themes. An 84 percent response rate was achieved, including 49 orthopedic and 12 plastic surgery program directors. There were significant differences in mean responses between the specialty groups in 11 of 27 scales. Only one scale, forearm fractures, contained items with a significantly stronger preference for essential rating among orthopedic surgeons. The other 10 scales contained items with a significantly higher preference for essential rating among plastic surgeons, most of which related to soft-tissue injury and reconstruction. The burn scale had the greatest discrepancy in opinion of essential ratings between the groups, followed by pedicled and free tissue transfer, and amputation and fingertip injuries. Despite being united under the subspecialty of hand surgery, program directors tend to emphasize clinical areas that are stressed in their respective primary disciplines. These differences promote the advantage of programs that provide exposure to both plastic surgery-trained and orthopedic surgery-trained hand surgeons.

Do Circumnuclear Dense Gas Disks Drive Mass Accretion onto Supermassive Black Holes?

NASA Astrophysics Data System (ADS)

Izumi, Takuma; Kawakatu, Nozomu; Kohno, Kotaro

2016-08-01

We present a positive correlation between the mass of dense molecular gas ({M}{{dense}}) of ˜100 pc scale circumnuclear disks (CNDs) and the black hole mass accretion rate ({\\dot{M}}{{BH}}) in a total of 10 Seyfert galaxies, based on data compiled from the literature and an archive (median aperture θ med = 220 pc). A typical {M}{{dense}} of CNDs is 107-8 {M}⊙ , estimated from the luminosity of the dense gas tracer, the HCN(1-0) emission line. Because dense molecular gas is the site of star formation, this correlation is virtually equivalent to the one between the nuclear star-formation rate and {\\dot{M}}{{BH}} revealed previously. Moreover, the {M}{{dense}}{--}{\\dot{M}}{{BH}} correlation was tighter for CND-scale gas than for the gas on kiloparsec or larger scales. This indicates that CNDs likely play an important role in fueling black holes, whereas greater than kiloparesec scale gas does not. To demonstrate a possible approach for studying the CND-scale accretion process with the Atacama Large Millimeter/submillimeter Array, we used a mass accretion model where angular momentum loss due to supernova explosions is vital. Based on the model prediction, we suggest that only the partial fraction of the mass accreted from the CND ({\\dot{M}}{{acc}}) is consumed as {\\dot{M}}{{BH}}. However, {\\dot{M}}{{acc}} agrees well with the total nuclear mass flow rate (I.e., {\\dot{M}}{{BH}} + outflow rate). Although these results are still tentative with large uncertainties, they support the view that star formation in CNDs can drive mass accretion onto supermassive black holes in Seyfert galaxies.

A Theoretical Basis for Entropy-Scaling Effects in Human Mobility Patterns

PubMed Central

2016-01-01

Characterizing how people move through space has been an important component of many disciplines. With the advent of automated data collection through GPS and other location sensing systems, researchers have the opportunity to examine human mobility at spatio-temporal resolution heretofore impossible. However, the copious and complex data collected through these logging systems can be difficult for humans to fully exploit, leading many researchers to propose novel metrics for encapsulating movement patterns in succinct and useful ways. A particularly salient proposed metric is the mobility entropy rate of the string representing the sequence of locations visited by an individual. However, mobility entropy rate is not scale invariant: entropy rate calculations based on measurements of the same trajectory at varying spatial or temporal granularity do not yield the same value, limiting the utility of mobility entropy rate as a metric by confounding inter-experimental comparisons. In this paper, we derive a scaling relationship for mobility entropy rate of non-repeating straight line paths from the definition of Lempel-Ziv compression. We show that the resulting formulation predicts the scaling behavior of simulated mobility traces, and provides an upper bound on mobility entropy rate under certain assumptions. We further show that this formulation has a maximum value for a particular sampling rate, implying that optimal sampling rates for particular movement patterns exist. PMID:27571423

The Rangeland Hydrology and Erosion Model

NASA Astrophysics Data System (ADS)

Nearing, M. A.

2016-12-01

The Rangeland Hydrology and Erosion Model (RHEM) is a process-based model that was designed to address rangelands conditions. RHEM is designed for government agencies, land managers and conservationists who need sound, science-based technology to model, assess, and predict runoff and erosion rates on rangelands and to assist in evaluating rangeland conservation practices effects. RHEM is an event-based model that estimates runoff, erosion, and sediment delivery rates and volumes at the spatial scale of the hillslope and the temporal scale of as single rainfall event. It represents erosion processes under normal and fire-impacted rangeland conditions. Moreover, it adopts a new splash erosion and thin sheet-flow transport equation developed from rangeland data, and it links the model hydrologic and erosion parameters with rangeland plant community by providing a new system of parameter estimation equations based on 204 plots at 49 rangeland sites distributed across 15 western U.S. states. A dynamic partial differential sediment continuity equation is used to model the total detachment rate of concentrated flow and rain splash and sheet flow. RHEM is also designed to be used as a calculator, or "engine", within other watershed scale models. From the research perspective RHEM acts as a vehicle for incorporating new scientific findings from rangeland infiltration, runoff, and erosion studies. Current applications of the model include: 1) a web site for general use (conservation planning, research, etc.), 2) National Resource Inventory reports to Congress, 3) as a computational engine within watershed scale models (e.g., KINEROS, HEC), 4) Ecological Site & State and Transition Descriptions, 5) proposed in 2015 to become part of the NRCS Desktop applications for field offices.

Minimax estimation of qubit states with Bures risk

NASA Astrophysics Data System (ADS)

Acharya, Anirudh; Guţă, Mădălin

2018-04-01

The central problem of quantum statistics is to devise measurement schemes for the estimation of an unknown state, given an ensemble of n independent identically prepared systems. For locally quadratic loss functions, the risk of standard procedures has the usual scaling of 1/n. However, it has been noticed that for fidelity based metrics such as the Bures distance, the risk of conventional (non-adaptive) qubit tomography schemes scales as 1/\\sqrt{n} for states close to the boundary of the Bloch sphere. Several proposed estimators appear to improve this scaling, and our goal is to analyse the problem from the perspective of the maximum risk over all states. We propose qubit estimation strategies based on separate adaptive measurements, and collective measurements, that achieve 1/n scalings for the maximum Bures risk. The estimator involving local measurements uses a fixed fraction of the available resource n to estimate the Bloch vector direction; the length of the Bloch vector is then estimated from the remaining copies by measuring in the estimator eigenbasis. The estimator based on collective measurements uses local asymptotic normality techniques which allows us to derive upper and lower bounds to its maximum Bures risk. We also discuss how to construct a minimax optimal estimator in this setup. Finally, we consider quantum relative entropy and show that the risk of the estimator based on collective measurements achieves a rate O(n-1log n) under this loss function. Furthermore, we show that no estimator can achieve faster rates, in particular the ‘standard’ rate n ‑1.

Assessing communication quality of consultations in primary care: initial reliability of the Global Consultation Rating Scale, based on the Calgary-Cambridge Guide to the Medical Interview.

PubMed

Burt, Jenni; Abel, Gary; Elmore, Natasha; Campbell, John; Roland, Martin; Benson, John; Silverman, Jonathan

2014-03-06

To investigate initial reliability of the Global Consultation Rating Scale (GCRS: an instrument to assess the effectiveness of communication across an entire doctor-patient consultation, based on the Calgary-Cambridge guide to the medical interview), in simulated patient consultations. Multiple ratings of simulated general practitioner (GP)-patient consultations by trained GP evaluators. UK primary care. 21 GPs and six trained GP evaluators. GCRS score. 6 GP raters used GCRS to rate randomly assigned video recordings of GP consultations with simulated patients. Each of the 42 consultations was rated separately by four raters. We considered whether a fixed difference between scores had the same meaning at all levels of performance. We then examined the reliability of GCRS using mixed linear regression models. We augmented our regression model to also examine whether there were systematic biases between the scores given by different raters and to look for possible order effects. Assessing the communication quality of individual consultations, GCRS achieved a reliability of 0.73 (95% CI 0.44 to 0.79) for two raters, 0.80 (0.54 to 0.85) for three and 0.85 (0.61 to 0.88) for four. We found an average difference of 1.65 (on a 0-10 scale) in the scores given by the least and most generous raters: adjusting for this evaluator bias increased reliability to 0.78 (0.53 to 0.83) for two raters; 0.85 (0.63 to 0.88) for three and 0.88 (0.69 to 0.91) for four. There were considerable order effects, with later consultations (after 15-20 ratings) receiving, on average, scores more than one point higher on a 0-10 scale. GCRS shows good reliability with three raters assessing each consultation. We are currently developing the scale further by assessing a large sample of real-world consultations.

Psychometric properties of the communication Confidence Rating Scale for Aphasia (CCRSA): phase 1.

PubMed

Cherney, Leora R; Babbitt, Edna M; Semik, Patrick; Heinemann, Allen W

2011-01-01

Confidence is a construct that has not been explored previously in aphasia research. We developed the Communication Confidence Rating Scale for Aphasia (CCRSA) to assess confidence in communicating in a variety of activities and evaluated its psychometric properties using rating scale (Rasch) analysis. The CCRSA was administered to 21 individuals with aphasia before and after participation in a computer-based language therapy study. Person reliability of the 8-item CCRSA was .77. The 5-category rating scale demonstrated monotonic increases in average measures from low to high ratings. However, one item ("I follow news, sports, stories on TV/movies") misfit the construct defined by the other items (mean square infit = 1.69, item-measure correlation = .41). Deleting this item improved reliability to .79; the 7 remaining items demonstrated excellent fit to the underlying construct, although there was a modest ceiling effect in this sample. Pre- to posttreatment changes on the 7-item CCRSA measure were statistically significant using a paired samples t test. Findings support the reliability and sensitivity of the CCRSA in assessing participants' self-report of communication confidence. Further evaluation of communication confidence is required with larger and more diverse samples.

Determining the Accuracy of Self-Report Versus Informant-Report Using the Conners' Adult ADHD Rating Scale.

PubMed

Alexander, Lisa; Liljequist, Laura

2016-04-01

The present research examined the validity of self-report versus informant-report in relation to a performance-based indicator of adult ADHD. Archival data from 118 participants (52 males, 66 females) were used to compare Conners' Adult ADHD Rating Scale-Self-Report: Long Format (CAARS-S:L) and Conners' Adult ADHD Rating Scale-Observer Report: Long Format (CAARS-O:L) with discrepancy scores calculated between the Wechsler Adult Intelligence Scale-Third Edition (WAIS-III) Verbal Comprehension Index - Working Memory Index (VCI - WMI) and Perceptual-Organizational Index - Processing Speed Index (POI - PSI) scaled scores. Neither the self- nor informant-report formats of the CAARS were better predictors of discrepancies between WAIS-III Index scores. Intercorrelations between the CAARS-S:L and CAARS-O:L revealed generally higher correlations between the same scales of different formats and among scales measuring externally visible symptoms. Furthermore, regression analysis indicated that both the CAARS-S:L and CAARS-O:L clinical scales contributed a significant proportion of variance in WAIS-III VCI - WMI discrepancy scores (14.7% and 16.4%, respectively). Results did not establish greater accuracy of self-report versus informant-report of ADHD symptomatology, rather demonstrate the need for multimodal assessment of ADHD in adults. © The Author(s) 2013.

Wearable sensor-based objective assessment of motor symptoms in Parkinson's disease.

PubMed

Ossig, Christiana; Antonini, Angelo; Buhmann, Carsten; Classen, Joseph; Csoti, Ilona; Falkenburger, Björn; Schwarz, Michael; Winkler, Jürgen; Storch, Alexander

2016-01-01

Effective management and development of new treatment strategies of motor symptoms in Parkinson's disease (PD) largely depend on clinical rating instruments like the Unified PD rating scale (UPDRS) and the modified abnormal involuntary movement scale (mAIMS). Regarding inter-rater variability and continuous monitoring, clinical rating scales have various limitations. Patient-administered questionnaires such as the PD home diary to assess motor stages and fluctuations in late-stage PD are frequently used in clinical routine and as clinical trial endpoints, but diary/questionnaire are tiring, and recall bias impacts on data quality, particularly in patients with cognitive dysfunction or depression. Consequently, there is a strong need for continuous and objective monitoring of motor symptoms in PD for improving therapeutic regimen and for usage in clinical trials. Recent advances in battery technology, movement sensors such as gyroscopes, accelerometers and information technology boosted the field of objective measurement of movement in everyday life and medicine using wearable sensors allowing continuous (long-term) monitoring. This systematic review summarizes the current wearable sensor-based devices to objectively assess the various motor symptoms of PD.

Quench in the 1D Bose-Hubbard model: Topological defects and excitations from the Kosterlitz-Thouless phase transition dynamics

PubMed Central

Dziarmaga, Jacek; Zurek, Wojciech H.

2014-01-01

Kibble-Zurek mechanism (KZM) uses critical scaling to predict density of topological defects and other excitations created in second order phase transitions. We point out that simply inserting asymptotic critical exponents deduced from the immediate vicinity of the critical point to obtain predictions can lead to results that are inconsistent with a more careful KZM analysis based on causality – on the comparison of the relaxation time of the order parameter with the “time distance” from the critical point. As a result, scaling of quench-generated excitations with quench rates can exhibit behavior that is locally (i.e., in the neighborhood of any given quench rate) well approximated by the power law, but with exponents that depend on that rate, and that are quite different from the naive prediction based on the critical exponents relevant for asymptotically long quench times. Kosterlitz-Thouless scaling (that governs e.g. Mott insulator to superfluid transition in the Bose-Hubbard model in one dimension) is investigated as an example of this phenomenon. PMID:25091996

Karolinska Psychodynamic Profile for Sexual Disorders: KAPP-SD. A proposal for a psychodynamic rating scale for sexual disorders.

PubMed

Soldati, Lorenzo; Köhl, John; Abraham, Georges; Bianchi Demicheli, Francesco; Wilczek, Alexander

2015-01-01

Our first objective in this paper was to review the literature on psychodynamic rating scales of sexual disorders. Our second objective, based on the findings from our review, was to develop a psychodynamic rating scale for people with sexual disorders: the KAPP-SD. We developed the KAPP-SD by modifying an existing psychodynamic rating scale, which assesses stable modes of mental functioning and character traits, the Karolinska Psychodynamic Profile (KAPP). We removed items 13 and 14 of the KAPP and replaced them with three other items-sexual fantasies, conceptions and role of gender identity, and conceptions and role of sexual orientation. These items are part of the assessment of an individual's sexuality and are used to evaluate a person with a sexual disorder psychodynamically. The KAPP-SD, a modified version of the KAPP, can be found in the Appendix. We developed the KAPP-SD in order to help sex therapists make a rigorous psychodynamic evaluation of persons with sexual disorders, which would give information on the prognosis and on the type of treatment to offer.

Hierarchical population monitoring of greater sage-grouse (Centrocercus urophasianus) in Nevada and California—Identifying populations for management at the appropriate spatial scale

USGS Publications Warehouse

Coates, Peter S.; Prochazka, Brian G.; Ricca, Mark A.; Wann, Gregory T.; Aldridge, Cameron L.; Hanser, Steven E.; Doherty, Kevin E.; O'Donnell, Michael S.; Edmunds, David R.; Espinosa, Shawn P.

2017-08-10

Population ecologists have long recognized the importance of ecological scale in understanding processes that guide observed demographic patterns for wildlife species. However, directly incorporating spatial and temporal scale into monitoring strategies that detect whether trajectories are driven by local or regional factors is challenging and rarely implemented. Identifying the appropriate scale is critical to the development of management actions that can attenuate or reverse population declines. We describe a novel example of a monitoring framework for estimating annual rates of population change for greater sage-grouse (Centrocercus urophasianus) within a hierarchical and spatially nested structure. Specifically, we conducted Bayesian analyses on a 17-year dataset (2000–2016) of lek counts in Nevada and northeastern California to estimate annual rates of population change, and compared trends across nested spatial scales. We identified leks and larger scale populations in immediate need of management, based on the occurrence of two criteria: (1) crossing of a destabilizing threshold designed to identify significant rates of population decline at a particular nested scale; and (2) crossing of decoupling thresholds designed to identify rates of population decline at smaller scales that decouple from rates of population change at a larger spatial scale. This approach establishes how declines affected by local disturbances can be separated from those operating at larger scales (for example, broad-scale wildfire and region-wide drought). Given the threshold output from our analysis, this adaptive management framework can be implemented readily and annually to facilitate responsive and effective actions for sage-grouse populations in the Great Basin. The rules of the framework can also be modified to identify populations responding positively to management action or demonstrating strong resilience to disturbance. Similar hierarchical approaches might be beneficial for other species occupying landscapes with heterogeneous disturbance and climatic regimes.

Modeling of copper sorption onto GFH and design of full-scale GFH adsorbers.

PubMed

Steiner, Michele; Pronk, Wouter; Boller, Markus A

2006-03-01

During rain events, copper wash-off occurring from copper roofs results in environmental hazards. In this study, columns filled with granulated ferric hydroxide (GFH) were used to treat copper-containing roof runoff. It was shown that copper could be removed to a high extent. A model was developed to describe this removal process. The model was based on the Two Region Model (TRM), extended with an additional diffusion zone. The extended model was able to describe the copper removal in long-term experiments (up to 125 days) with variable flow rates reflecting realistic runoff events. The four parameters of the model were estimated based on data gained with specific column experiments according to maximum sensitivity for each parameter. After model validation, the parameter set was used for the design of full-scale adsorbers. These full-scale adsorbers show high removal rates during extended periods of time.

THE IMPACT OF SCALING FACTOR VARIABILITY ON RISK-RELEVANT TOXICOKINETIC OUTCOMES IN CHILDREN: A CASE STUDY USING BROMODICHLOROMETHANE (BDCM)

EPA Science Inventory

Biotransformation rates (Vmax) extrapolated from in vitro data are used increasingly in human physiologically based pharmacokinetic (PBPK) models. Extrapolation of Vmax from in vitro data requires use of scaling factors, including mg of microsomal protein/g liver (MPPGL), nmol of...

Dropout Proneness in Appalachia. Research Series 3.

ERIC Educational Resources Information Center

Mink, Oscar G.; Barker, Laurence W.

Two aids used in the identification of potential dropouts are examined. The Mink Scale (a teacher-rated scale) is based on classification of social, psychological, and educational forces related to dropout proneness: (1) academic ability and performance, (2) negative identification with education, (3) family and socioeconomic status, and (4)…

Heart rate detection from an electronic weighing scale.

PubMed

González-Landaeta, R; Casas, O; Pallàs-Areny, R

2007-01-01

We propose a novel technique for heart rate detection on a subject that stands on a common electronic weighing scale. The detection relies on sensing force variations related to the blood acceleration in the aorta, works even if wearing footwear, and does not require any sensors attached to the body. We have applied our method to three different weighing scales, and estimated whether their sensitivity and frequency response suited heart rate detection. Scale sensitivities were from 490 nV/V/N to 1670 nV/V/N, all had an underdamped transient response and their dynamic gain error was below 19% at 10 Hz, which are acceptable values for heart rate estimation. We also designed a pulse detection system based on off-the-shelf integrated circuits, whose gain was about 70x10(3) and able to sense force variations about 240 mN. The signal-to-noise ratio (SNR) of the main peaks of the pulse signal detected was higher than 48 dB, which is large enough to estimate the heart rate by simple signal processing methods. To validate the method, the ECG and the force signal were simultaneously recorded on 12 volunteers. The maximal error obtained from heart rates determined from these two signals was +/-0.6 beats/minute.

Differentiating causality and correlation in allometric scaling: ant colony size drives metabolic hypometry

PubMed Central

Ochs, Alison; Fewell, Jennifer H.; Harrison, Jon F.

2017-01-01

Metabolic rates of individual animals and social insect colonies generally scale hypometrically, with mass-specific metabolic rates decreasing with increasing size. Although this allometry has wide ranging effects on social behaviour, ecology and evolution, its causes remain controversial. Because it is difficult to experimentally manipulate body size of organisms, most studies of metabolic scaling depend on correlative data, limiting their ability to determine causation. To overcome this limitation, we experimentally reduced the size of harvester ant colonies (Pogonomyrmex californicus) and quantified the consequent increase in mass-specific metabolic rates. Our results clearly demonstrate a causal relationship between colony size and hypometric changes in metabolic rate that could not be explained by changes in physical density. These findings provide evidence against prominent models arguing that the hypometric scaling of metabolic rate is primarily driven by constraints on resource delivery or surface area/volume ratios, because colonies were provided with excess food and colony size does not affect individual oxygen or nutrient transport. We found that larger colonies had lower median walking speeds and relatively more stationary ants and including walking speed as a variable in the mass-scaling allometry greatly reduced the amount of residual variation in the model, reinforcing the role of behaviour in metabolic allometry. Following the experimental size reduction, however, the proportion of stationary ants increased, demonstrating that variation in locomotory activity cannot solely explain hypometric scaling of metabolic rates in these colonies. Based on prior studies of this species, the increase in metabolic rate in size-reduced colonies could be due to increased anabolic processes associated with brood care and colony growth. PMID:28228514

The effect of client ethnicity on clinical interpretation of the MMPI-2.

PubMed

Knaster, Cara A; Micucci, Joseph A

2013-02-01

Client ethnicity has been shown to affect clinicians' diagnostic impressions. However, it is not known whether interpretation of the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) clinical scales is affected by ethnic bias. In this study, clinicians (82 males, 60 females) provided severity ratings for six symptoms based on three MMPI-2 profiles (representing the 27/72, 49/94, and 68/86 code-types) with the ethnicity of the client randomly assigned as either African American or Caucasian. To determine whether symptom severity ratings based on MMPI-2 profiles were affected by ethnicity, a 3 (code-type) × 2 (ethnicity) MANOVA was performed. Neither the main effect for ethnicity nor the ethnicity × code-type interaction was significant. These results indicated that the symptom severity ratings based on the MMPI-2 clinical scales were not affected by the client's identification as African American or Caucasian. Future studies are needed to explore the interpretation of profiles from clients representing other ethnic groups and for female clients.

Estimating Rain Rates from Tipping-Bucket Rain Gauge Measurements

NASA Technical Reports Server (NTRS)

Wang, Jianxin; Fisher, Brad L.; Wolff, David B.

2007-01-01

This paper describes the cubic spline based operational system for the generation of the TRMM one-minute rain rate product 2A-56 from Tipping Bucket (TB) gauge measurements. Methodological issues associated with applying the cubic spline to the TB gauge rain rate estimation are closely examined. A simulated TB gauge from a Joss-Waldvogel (JW) disdrometer is employed to evaluate effects of time scales and rain event definitions on errors of the rain rate estimation. The comparison between rain rates measured from the JW disdrometer and those estimated from the simulated TB gauge shows good overall agreement; however, the TB gauge suffers sampling problems, resulting in errors in the rain rate estimation. These errors are very sensitive to the time scale of rain rates. One-minute rain rates suffer substantial errors, especially at low rain rates. When one minute rain rates are averaged to 4-7 minute or longer time scales, the errors dramatically reduce. The rain event duration is very sensitive to the event definition but the event rain total is rather insensitive, provided that the events with less than 1 millimeter rain totals are excluded. Estimated lower rain rates are sensitive to the event definition whereas the higher rates are not. The median relative absolute errors are about 22% and 32% for 1-minute TB rain rates higher and lower than 3 mm per hour, respectively. These errors decrease to 5% and 14% when TB rain rates are used at 7-minute scale. The radar reflectivity-rainrate (Ze-R) distributions drawn from large amount of 7-minute TB rain rates and radar reflectivity data are mostly insensitive to the event definition.

The independence of physical attractiveness and symptoms of depression in a female twin population.

PubMed

McGovern, R J; Neale, M C; Kendler, K S

1996-03-01

The relationship between physical attractiveness and symptoms of depression was investigated in a general population simple of 1,100 female twins. Photographs were rated by 4 raters. Symptoms of depression were measured by the Depression sub-scale of the SCL-54, by a self-rating based on the DSM-III-R, and by an MD diagnosis based on a structured interview (SCID). No relationships between ratings of physical attractiveness and symptoms of depression were found.

When less is more: validating a brief scale to rate interprofessional team competencies.

PubMed

Lie, Désirée A; Richter-Lagha, Regina; Forest, Christopher P; Walsh, Anne; Lohenry, Kevin

2017-01-01

There is a need for validated and easy-to-apply behavior-based tools for assessing interprofessional team competencies in clinical settings. The seven-item observer-based Modified McMaster-Ottawa scale was developed for the Team Objective Structured Clinical Encounter (TOSCE) to assess individual and team performance in interprofessional patient encounters. We aimed to improve scale usability for clinical settings by reducing item numbers while maintaining generalizability; and to explore the minimum number of observed cases required to achieve modest generalizability for giving feedback. We administered a two-station TOSCE in April 2016 to 63 students split into 16 newly-formed teams, each consisting of four professions. The stations were of similar difficulty. We trained sixteen faculty to rate two teams each. We examined individual and team performance scores using generalizability (G) theory and principal component analysis (PCA). The seven-item scale shows modest generalizability (.75) with individual scores. PCA revealed multicollinearity and singularity among scale items and we identified three potential items for removal. Reducing items for individual scores from seven to four (measuring Collaboration, Roles, Patient/Family-centeredness, and Conflict Management) changed scale generalizability from .75 to .73. Performance assessment with two cases is associated with reasonable generalizability (.73). Students in newly-formed interprofessional teams show a learning curve after one patient encounter. Team scores from a two-station TOSCE demonstrate low generalizability whether the scale consisted of four (.53) or seven items (.55). The four-item Modified McMaster-Ottawa scale for assessing individual performance in interprofessional teams retains the generalizability and validity of the seven-item scale. Observation of students in teams interacting with two different patients provides reasonably reliable ratings for giving feedback. The four-item scale has potential for assessing individual student skills and the impact of IPE curricula in clinical practice settings. IPE: Interprofessional education; SP: Standardized patient; TOSCE: Team objective structured clinical encounter.

Distinct patterns of brain atrophy in Genetic Frontotemporal Dementia Initiative (GENFI) cohort revealed by visual rating scales.

PubMed

Fumagalli, Giorgio G; Basilico, Paola; Arighi, Andrea; Bocchetta, Martina; Dick, Katrina M; Cash, David M; Harding, Sophie; Mercurio, Matteo; Fenoglio, Chiara; Pietroboni, Anna M; Ghezzi, Laura; van Swieten, John; Borroni, Barbara; de Mendonça, Alexandre; Masellis, Mario; Tartaglia, Maria C; Rowe, James B; Graff, Caroline; Tagliavini, Fabrizio; Frisoni, Giovanni B; Laforce, Robert; Finger, Elizabeth; Sorbi, Sandro; Scarpini, Elio; Rohrer, Jonathan D; Galimberti, Daniela

2018-05-24

In patients with frontotemporal dementia, it has been shown that brain atrophy occurs earliest in the anterior cingulate, insula and frontal lobes. We used visual rating scales to investigate whether identifying atrophy in these areas may be helpful in distinguishing symptomatic patients carrying different causal mutations in the microtubule-associated protein tau (MAPT), progranulin (GRN) and chromosome 9 open reading frame (C9ORF72) genes. We also analysed asymptomatic carriers to see whether it was possible to visually identify brain atrophy before the appearance of symptoms. Magnetic resonance imaging of 343 subjects (63 symptomatic mutation carriers, 132 presymptomatic mutation carriers and 148 control subjects) from the Genetic Frontotemporal Dementia Initiative study were analysed by two trained raters using a protocol of six visual rating scales that identified atrophy in key regions of the brain (orbitofrontal, anterior cingulate, frontoinsula, anterior and medial temporal lobes and posterior cortical areas). Intra- and interrater agreement were greater than 0.73 for all the scales. Voxel-based morphometric analysis demonstrated a strong correlation between the visual rating scale scores and grey matter atrophy in the same region for each of the scales. Typical patterns of atrophy were identified: symmetric anterior and medial temporal lobe involvement for MAPT, asymmetric frontal and parietal loss for GRN, and a more widespread pattern for C9ORF72. Presymptomatic MAPT carriers showed greater atrophy in the medial temporal region than control subjects, but the visual rating scales could not identify presymptomatic atrophy in GRN or C9ORF72 carriers. These simple-to-use and reproducible scales may be useful tools in the clinical setting for the discrimination of different mutations of frontotemporal dementia, and they may even help to identify atrophy prior to onset in those with MAPT mutations.

Effects of operation parameters on nutrient removal from wastewater and high-protein biomass production in a duckweed-based (Lemma aequinoctialis) pilot-scale system.

PubMed

Zhao, Yonggui; Fang, Yang; Jin, Yanling; Huang, Jun; Bao, Shu; He, Zhiming; Wang, Feng; Zhao, Hai

2014-01-01

The effects of water depth, coverage rate and harvest regime on nutrient removal from wastewater and high-protein biomass production were assessed in a duckweed-based (Lemna aequinoctialis) pilot-scale wastewater treatment system (10 basins × 12 m(2)) that is located near Dianchi Lake in China. The results indicated that a water depth of 50 cm, a coverage rate of 150% and a harvest regime of 4 days were preferable conditions, under which excellent records of high-protein duckweed (dry matter production of 6.65 g/m(2)/d with crude protein content of 36.16% and phosphorus content of 1.46%) were obtained at a temperature of 12-21 °C. At the same time, the system achieved a removal efficiency of 66.16, 23.1, 48.3 and 76.52% for NH4(+)-N, TN, TP and turbidity, respectively, with the considerable removal rate of 0.465 g/m(2)/d for TN and 0.134 g/m(2)/d for TP at a hydraulic retention time of 6 days. In additionally, it was found that a lower duckweed density could lead to higher dissolved oxygen in the water and then a higher removal percentage of NH4(+)-N by nitrobacteria. This study obtains the preferable operation conditions for wastewater treatment and high-protein biomass production in a duckweed-based pilot-scale system, supplying an important reference for further large-scale applications of duckweed.

Addition of silicon improves oxidation resistance of nickel based superalloys

NASA Technical Reports Server (NTRS)

Lowell, C. E.; Miner, R. V., Jr.

1974-01-01

Specific weight changes of nickel-base superalloy B-1900 and B-1900 + 1% Si specimens were tested at 1273 K. B-1900 was losing weight at an increasing rate due to spalling of oxide scale while B-1900 + 1% Si was still gaining weight at low, nearly constant rate. Similar comparison in weight change was observed for specimens tested at 1373 K.

One State's Systems Change Efforts to Reduce Child Care Expulsion: Taking the Pyramid Model to Scale

ERIC Educational Resources Information Center

Vinh, Megan; Strain, Phil; Davidon, Sarah; Smith, Barbara J.

2016-01-01

This article describes the efforts funded by the state of Colorado to address unacceptably high rates of expulsion from child care. Based on the results of a 2006 survey, the state of Colorado launched two complementary policy initiatives in 2009 to impact expulsion rates and to improve the use of evidence-based practices related to challenging…

The Managing Emergencies in Paediatric Anaesthesia global rating scale is a reliable tool for simulation-based assessment in pediatric anesthesia crisis management.

PubMed

Everett, Tobias C; Ng, Elaine; Power, Daniel; Marsh, Christopher; Tolchard, Stephen; Shadrina, Anna; Bould, Matthew D

2013-12-01

The use of simulation-based assessments for high-stakes physician examinations remains controversial. The Managing Emergencies in Paediatric Anaesthesia course uses simulation to teach evidence-based management of anesthesia crises to trainee anesthetists in the United Kingdom (UK) and Canada. In this study, we investigated the feasibility and reliability of custom-designed scenario-specific performance checklists and a global rating scale (GRS) assessing readiness for independent practice. After research ethics board approval, subjects were videoed managing simulated pediatric anesthesia crises in a single Canadian teaching hospital. Each subject was randomized to two of six different scenarios. All 60 scenarios were subsequently rated by four blinded raters (two in the UK, two in Canada) using the checklists and GRS. The actual and predicted reliability of the tools was calculated for different numbers of raters using the intraclass correlation coefficient (ICC) and the Spearman-Brown prophecy formula. Average measures ICCs ranged from 'substantial' to 'near perfect' (P ≤ 0.001). The reliability of the checklists and the GRS was similar. Single measures ICCs showed more variability than average measures ICC. At least two raters would be required to achieve acceptable reliability. We have established the reliability of a GRS to assess the management of simulated crisis scenarios in pediatric anesthesia, and this tool is feasible within the setting of a research study. The global rating scale allows raters to make a judgement regarding a participant's readiness for independent practice. These tools may be used in the future research examining simulation-based assessment. © 2013 John Wiley & Sons Ltd.

Shallow Cumulus Variability at the ARM Eastern North Atlantic Site

NASA Astrophysics Data System (ADS)

Lamer, K.; Kollias, P.; Ghate, V. P.; Luke, E. P.

2016-12-01

Cumulus clouds play a critical role in modulating the radiative and hydrological budget of the lower troposphere. These clouds, which are ubiquitous in regions of large-scale subsidence over the oceans, tend to be misrepresented in global climate models. Island-based, long-term, high-resolution ground-based observations can provide valuable insights on the factors controlling their macroscopic and microphysical properties and subsequenlty assist in model evaluation and guidance. Previous studies, limited to fair-weather cumuli over land, revealed that their fractional coverage is only weakly correlated with several parameters; the best ones being complex dynamical characteristics of the subcloud layer (vertical velocity skewness and eddy coherence). Other studies noted a relationship between cumuli depth and their propensity to precipitate. The current study will expand on such analysis by performing detail characterization of the full spectrum of shallow cumulus fields from non-precipitating to precipitating in the context of the large-scale forcing (i.e. thermodynamic structure and subsidence rates). Two years of ground-based remote sensing observations collected at the Atmospheric Radiation Measurement (ARM) Eastern North Atlantic (ENA) site are used to document macroscopic (cloud depth, cord length, cover), microphysical (liquid water path, cloud base rain rate) and dynamical (cloud base mass flux, eddy dissipation rate) cumuli properties. The observed variability in shallow cumulus is examined in relation to the variability of the large-scale environment as captured by the humidity profile, the magnitude of the low-level horizontal winds and near-surface aerosol conditions.

Reducing aeration energy consumption in a large-scale membrane bioreactor: Process simulation and engineering application.

PubMed

Sun, Jianyu; Liang, Peng; Yan, Xiaoxu; Zuo, Kuichang; Xiao, Kang; Xia, Junlin; Qiu, Yong; Wu, Qing; Wu, Shijia; Huang, Xia; Qi, Meng; Wen, Xianghua

2016-04-15

Reducing the energy consumption of membrane bioreactors (MBRs) is highly important for their wider application in wastewater treatment engineering. Of particular significance is reducing aeration in aerobic tanks to reduce the overall energy consumption. This study proposed an in situ ammonia-N-based feedback control strategy for aeration in aerobic tanks; this was tested via model simulation and through a large-scale (50,000 m(3)/d) engineering application. A full-scale MBR model was developed based on the activated sludge model (ASM) and was calibrated to the actual MBR. The aeration control strategy took the form of a two-step cascaded proportion-integration (PI) feedback algorithm. Algorithmic parameters were optimized via model simulation. The strategy achieved real-time adjustment of aeration amounts based on feedback from effluent quality (i.e., ammonia-N). The effectiveness of the strategy was evaluated through both the model platform and the full-scale engineering application. In the former, the aeration flow rate was reduced by 15-20%. In the engineering application, the aeration flow rate was reduced by 20%, and overall specific energy consumption correspondingly reduced by 4% to 0.45 kWh/m(3)-effluent, using the present practice of regulating the angle of guide vanes of fixed-frequency blowers. Potential energy savings are expected to be higher for MBRs with variable-frequency blowers. This study indicated that the ammonia-N-based aeration control strategy holds promise for application in full-scale MBRs. Copyright © 2016 Elsevier Ltd. All rights reserved.

Bullying and Victimization Rates among Gifted and High-Achieving Students

ERIC Educational Resources Information Center

Peters, Megan Parker; Bain, Sherry K.

2011-01-01

Bullying and victimization rates among 90 gifted and nongifted, high-achieving (HA) high school students were assessed by using the Reynolds Bully Victimization Scale (BVS; W. M. Reynolds, 2003). The mean scores indicate that gifted and HA high school students bully others and are victimized by others generally at unelevated rates based on BVS…

Adjacent-Categories Mokken Models for Rater-Mediated Assessments

PubMed Central

Wind, Stefanie A.

2016-01-01

Molenaar extended Mokken’s original probabilistic-nonparametric scaling models for use with polytomous data. These polytomous extensions of Mokken’s original scaling procedure have facilitated the use of Mokken scale analysis as an approach to exploring fundamental measurement properties across a variety of domains in which polytomous ratings are used, including rater-mediated educational assessments. Because their underlying item step response functions (i.e., category response functions) are defined using cumulative probabilities, polytomous Mokken models can be classified as cumulative models based on the classifications of polytomous item response theory models proposed by several scholars. In order to permit a closer conceptual alignment with educational performance assessments, this study presents an adjacent-categories variation on the polytomous monotone homogeneity and double monotonicity models. Data from a large-scale rater-mediated writing assessment are used to illustrate the adjacent-categories approach, and results are compared with the original formulations. Major findings suggest that the adjacent-categories models provide additional diagnostic information related to individual raters’ use of rating scale categories that is not observed under the original formulation. Implications are discussed in terms of methods for evaluating rating quality. PMID:29795916

A High-Performance Sintered Iron Electrode for Rechargeable Alkaline Batteries to Enable Large-Scale Energy Storage

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yang, Chenguang; Manohar, Aswin K.; Narayanan, S. R.

Iron-based alkaline rechargeable batteries such as iron-air and nickel-iron batteries are particularly attractive for large-scale energy storage because these batteries can be relatively inexpensive, environment- friendly, and also safe. Therefore, our study has focused on achieving the essential electrical performance and cycling properties needed for the widespread use of iron-based alkaline batteries in stationary and distributed energy storage applications.We have demonstrated for the first time, an advanced sintered iron electrode capable of 3500 cycles of repeated charge and discharge at the 1-hour rate and 100% depth of discharge in each cycle, and an average Coulombic efficiency of over 97%. Suchmore » a robust and efficient rechargeable iron electrode is also capable of continuous discharge at rates as high as 3C with no noticeable loss in utilization. We have shown that the porosity, pore size and thickness of the sintered electrode can be selected rationally to optimize specific capacity, rate capability and robustness. As a result, these advances in the electrical performance and durability of the iron electrode enables iron-based alkaline batteries to be a viable technology solution for meeting the dire need for large-scale electrical energy storage.« less

A High-Performance Sintered Iron Electrode for Rechargeable Alkaline Batteries to Enable Large-Scale Energy Storage

DOE PAGES

Yang, Chenguang; Manohar, Aswin K.; Narayanan, S. R.

2017-01-07

Iron-based alkaline rechargeable batteries such as iron-air and nickel-iron batteries are particularly attractive for large-scale energy storage because these batteries can be relatively inexpensive, environment- friendly, and also safe. Therefore, our study has focused on achieving the essential electrical performance and cycling properties needed for the widespread use of iron-based alkaline batteries in stationary and distributed energy storage applications.We have demonstrated for the first time, an advanced sintered iron electrode capable of 3500 cycles of repeated charge and discharge at the 1-hour rate and 100% depth of discharge in each cycle, and an average Coulombic efficiency of over 97%. Suchmore » a robust and efficient rechargeable iron electrode is also capable of continuous discharge at rates as high as 3C with no noticeable loss in utilization. We have shown that the porosity, pore size and thickness of the sintered electrode can be selected rationally to optimize specific capacity, rate capability and robustness. As a result, these advances in the electrical performance and durability of the iron electrode enables iron-based alkaline batteries to be a viable technology solution for meeting the dire need for large-scale electrical energy storage.« less

Transition of temporal scaling behavior in percolation assisted shear-branching structure during plastic deformation

DOE PAGES

Ren, Jingli; Chen, Cun; Wang, Gang; ...

2017-03-22

This study explores the temporal scaling behavior induced shear-branching structure in response to variant temperatures and strain rates during plastic deformation of Zr-based bulk metallic glass (BMG). The data analysis based on the compression tests suggests that there are two states of shear-branching structures: the fractal structure with a long-range order at an intermediate temperature of 223 K and a larger strain rate of 2.5 × 10 –2 s –1; the disordered structure dominated at other temperature and strain rate. It can be deduced from the percolation theory that the compressive ductility, ec, can reach the maximum value at themore » intermediate temperature. Furthermore, a dynamical model involving temperature is given for depicting the shear-sliding process, reflecting the plastic deformation has fractal structure at the temperature of 223 K and strain rate of 2.5 × 10 –2 s –1.« less

The effect of simulation-based crew resource management training on measurable teamwork and communication among interprofessional teams caring for postoperative patients.

PubMed

Paull, Douglas E; Deleeuw, Lori D; Wolk, Seth; Paige, John T; Neily, Julia; Mills, Peter D

2013-11-01

Many adverse events in health care are caused by teamwork and communication breakdown. This study was conducted to investigate the effect of a point-of-care simulation-based team training curriculum on measurable teamwork and communication skills in staff caring for postoperative patients. Twelve facilities involving 334 perioperative surgical staff underwent simulation-based training. Pretest and posttest self-report data included the Self-Efficacy of Teamwork Competencies Scale. Observational data were captured with the Clinical Teamwork Scale. Teamwork scores (measured on a five-point Likert scale) improved for all eight survey questions by an average of 18% (3.7 to 4.4, p < .05). The observed communication rating (scale of 1 to 10) increased by 16% (5.6 to 6.4, p < .05). Simulation-based team training for staff caring for perioperative patients is associated with measurable improvements in teamwork and communication. Copyright 2013, SLACK Incorporated.

The Clinical Research Center for Depression Study: Baseline Characteristics of a Korean Long-Term Hospital-Based Observational Collaborative Prospective Cohort Study

PubMed Central

Kim, Tae-Suk; Jeong, Seung Hee; Kim, Jung-Bum; Lee, Min-Soo; Kim, Jae-Min; Yim, Hyeon-Woo

2011-01-01

Objective The Clinical Research Center for Depression (CRESCEND) study is a 9-year observational collaborative prospective cohort study for the clinical outcomes in participants with depressive disorders in Korea. In this study, we examined the baseline characteristics of the depressive participants as the hospital-based cohort. Methods Participants were assessed using various instruments including the Clinical Global Impression scale, 17-item Hamilton Depression Rating Scale (HDRS-17), Hamilton Anxiety Rating Scale, Brief Psychiatric Rating Scale, Social and Occupational Functioning Assessment Scale, Beck Depression Inventory-Second Edition, Scale for Suicide Ideation, and World Health Organization Quality of Life assessment instruments-abbreviated version. Also, personal histories of medical and psychiatric illnesses and the range of socio-epidemiologic and clinical data were collected from each participant. Results One thousand one hundred eighty three participants were recruited from 18 hospitals. The mean age of the participants was 47.9±15.9 year-old, 74.4% were female, 82.9% had been diagnosed of major depressive disorder, 40.9% were experiencing their first depressive episode, and 21.4% had a past history of suicide attempts. The majority (85.3%) of the participants were moderately to severely ill. The average HDRS-17 was 19.8±6.1. Significant gender differences at baseline were shown in age, education, marriage, employment, religion, and first depressive episode. Conclusion The baseline findings in the CRESCEND study showed some different characteristics of depression in Korea, suggesting a possibility of ethnic and cultural factors in depression. PMID:21519530

Simultaneous estimation of local-scale and flow path-scale dual-domain mass transfer parameters using geoelectrical monitoring

USGS Publications Warehouse

Briggs, Martin A.; Day-Lewis, Frederick D.; Ong, John B.; Curtis, Gary P.; Lane, John W.

2013-01-01

Anomalous solute transport, modeled as rate-limited mass transfer, has an observable geoelectrical signature that can be exploited to infer the controlling parameters. Previous experiments indicate the combination of time-lapse geoelectrical and fluid conductivity measurements collected during ionic tracer experiments provides valuable insight into the exchange of solute between mobile and immobile porosity. Here, we use geoelectrical measurements to monitor tracer experiments at a former uranium mill tailings site in Naturita, Colorado. We use nonlinear regression to calibrate dual-domain mass transfer solute-transport models to field data. This method differs from previous approaches by calibrating the model simultaneously to observed fluid conductivity and geoelectrical tracer signals using two parameter scales: effective parameters for the flow path upgradient of the monitoring point and the parameters local to the monitoring point. We use regression statistics to rigorously evaluate the information content and sensitivity of fluid conductivity and geophysical data, demonstrating multiple scales of mass transfer parameters can simultaneously be estimated. Our results show, for the first time, field-scale spatial variability of mass transfer parameters (i.e., exchange-rate coefficient, porosity) between local and upgradient effective parameters; hence our approach provides insight into spatial variability and scaling behavior. Additional synthetic modeling is used to evaluate the scope of applicability of our approach, indicating greater range than earlier work using temporal moments and a Lagrangian-based Damköhler number. The introduced Eulerian-based Damköhler is useful for estimating tracer injection duration needed to evaluate mass transfer exchange rates that range over several orders of magnitude.

Power Calculations and Placebo Effect for Future Clinical Trials in Progressive Supranuclear Palsy

PubMed Central

Stamelou, Maria; Schöpe, Jakob; Wagenpfeil, Stefan; Ser, Teodoro Del; Bang, Jee; Lobach, Iryna Y.; Luong, Phi; Respondek, Gesine; Oertel, Wolfgang H.; Boxer, Adam L.; Höglinger, Günter U.

2016-01-01

Background Two recent randomized, placebo-controlled trials of putative disease-modifying agents (davunetide, tideglusib) in progressive supranuclear palsy (PSP) failed to show efficacy, but generated data relevant for future trials. Methods We provide sample size calculations based on data collected in 187 PSP patients assigned to placebo in these trials. A placebo effect was calculated. Results The total PSP-Rating Scale required the least number of patients per group (N = 51) to detect a 50% change in the 1-year progression and 39 when including patients with ≤ 5 years disease duration. The Schwab and England Activities of Daily Living required 70 patients per group and was highly correlated with the PSP-Rating Scale. A placebo effect was not detected in these scales. Conclusions We propose the 1-year PSP-Rating Scale score change as the single primary readout in clinical neuroprotective or disease-modifying trials. The Schwab and England Activities of Daily Living could be used as a secondary outcome. PMID:26948290

Erosive Augmentation of Solid Propellant Burning Rate: Motor Size Scaling Effect

NASA Technical Reports Server (NTRS)

Strand, L. D.; Cohen, Norman S.

1990-01-01

Two different independent variable forms, a difference form and a ratio form, were investigated for correlating the normalized magnitude of the measured erosive burning rate augmentation above the threshold in terms of the amount that the driving parameter (mass flux or Reynolds number) exceeds the threshold value for erosive augmentation at the test condition. The latter was calculated from the previously determined threshold correlation. Either variable form provided a correlation for each of the two motor size data bases individually. However, the data showed a motor size effect, supporting the general observation that the magnitude of erosive burning rate augmentation is reduced for larger rocket motors. For both independent variable forms, the required motor size scaling was attained by including the motor port radius raised to a power in the independent parameter. A boundary layer theory analysis confirmed the experimental finding, but showed that the magnitude of the scale effect is itself dependent upon scale, tending to diminish with increasing motor size.

Temperature-dependent body size effects determine population responses to climate warming.

PubMed

Lindmark, Max; Huss, Magnus; Ohlberger, Jan; Gårdmark, Anna

2018-02-01

Current understanding of animal population responses to rising temperatures is based on the assumption that biological rates such as metabolism, which governs fundamental ecological processes, scale independently with body size and temperature, despite empirical evidence for interactive effects. Here, we investigate the consequences of interactive temperature- and size scaling of vital rates for the dynamics of populations experiencing warming using a stage-structured consumer-resource model. We show that interactive scaling alters population and stage-specific responses to rising temperatures, such that warming can induce shifts in population regulation and stage-structure, influence community structure and govern population responses to mortality. Analysing experimental data for 20 fish species, we found size-temperature interactions in intraspecific scaling of metabolic rate to be common. Given the evidence for size-temperature interactions and the ubiquity of size structure in animal populations, we argue that accounting for size-specific temperature effects is pivotal for understanding how warming affects animal populations and communities. © 2017 The Authors. Ecology Letters published by CNRS and John Wiley & Sons Ltd.

DIVERSITY: A new method for evaluating sensitivity of groundwater to contamination

NASA Astrophysics Data System (ADS)

Ray, J. A.; O'Dell, P. W.

1993-12-01

This study outlines an improved method, DIVERSITY, for delineating and rating groundwater sensitivity. It is an acronym for DIspersion/VElocity-Rated SensitivITY, which is based on an assessment of three aquifer characteristics: recharge potential, flow velocity, and flow directions. The primary objective of this method is to produce sensitivity maps at the county or state scale that illustrate intrinsic potential for contamination of the uppermost aquifer. Such maps can be used for recognition of aquifer sensitivity and for protection of groundwater quality. We suggest that overriding factors that strongly affect one or more of the three basic aquifer characteristics may systematically elevate or lower the sensitivity rating. The basic method employs a three-step procedure: (1) Hydrogeologic settings are delineated on the basis of geology and groundwater recharge/discharge position within a terrane. (2) A sensitivity envelope or model for each setting is outlined on a three-component rating graph. (3) Sensitivity ratings derived from the envelope are extrapolated to hydrogeologic setting polygons utilizing overriding and key factors, when appropriate. The three-component sensitivity rating graph employs two logarithmic scales and a relative area scale on which measured and estimated values may be plotted. The flow velocity scale ranging from 0.01 to more than 10,000 m/d is the keystone of the rating graph. Whenever possible, actual time-of-travel values are plotted on the velocity scale to bracket the position of a sensitivity envelope. The DIVERSITY method was developed and tested for statewide use in Kentucky, but we believe it is also practical and applicable for use in almost any other area.

Reynolds number scaling of straining motions in turbulence

NASA Astrophysics Data System (ADS)

Elsinga, Gerrit; Ishihara, T.; Goudar, M. V.; da Silva, C. B.; Hunt, J. C. R.

2017-11-01

Strain is an important fluid motion in turbulence as it is associated with the kinetic energy dissipation rate, vorticity stretching, and the dispersion of passive scalars. The present study investigates the scaling of the turbulent straining motions by evaluating the flow in the eigenframe of the local strain-rate tensor. The analysis is based on DNS of homogeneous isotropic turbulence covering a Reynolds number range Reλ = 34.6 - 1131. The resulting flow pattern reveals a shear layer containing tube-like vortices and a dissipation sheet, which both scale on the Kolmogorov length scale, η. The vorticity stretching motions scale on the Taylor length scale, while the flow outside the shear layer scales on the integral length scale. These scaling results are consistent with those in wall-bounded flow, which suggests a quantitative universality between the different flows. The overall coherence length of the vorticity is 120 η in all directions, which is considerably larger than the typical size of individual vortices, and reflects the importance of spatial organization at the small scales. Transitions in flow structure are identified at Reλ 45 and 250. Below these respective Reynolds numbers, the small-scale motions and the vorticity stretching motions appear underdeveloped.

Deviations from uniform power law scaling in nonstationary time series

NASA Technical Reports Server (NTRS)

Viswanathan, G. M.; Peng, C. K.; Stanley, H. E.; Goldberger, A. L.

1997-01-01

A classic problem in physics is the analysis of highly nonstationary time series that typically exhibit long-range correlations. Here we test the hypothesis that the scaling properties of the dynamics of healthy physiological systems are more stable than those of pathological systems by studying beat-to-beat fluctuations in the human heart rate. We develop techniques based on the Fano factor and Allan factor functions, as well as on detrended fluctuation analysis, for quantifying deviations from uniform power-law scaling in nonstationary time series. By analyzing extremely long data sets of up to N = 10(5) beats for 11 healthy subjects, we find that the fluctuations in the heart rate scale approximately uniformly over several temporal orders of magnitude. By contrast, we find that in data sets of comparable length for 14 subjects with heart disease, the fluctuations grow erratically, indicating a loss of scaling stability.

Dysautonomia rating scales in Parkinson's disease: sialorrhea, dysphagia, and constipation--critique and recommendations by movement disorders task force on rating scales for Parkinson's disease.

PubMed

Evatt, Marian L; Chaudhuri, K Ray; Chou, Kelvin L; Cubo, Ester; Hinson, Vanessa; Kompoliti, Katie; Yang, Chengwu; Poewe, Werner; Rascol, Olivier; Sampaio, Cristina; Stebbins, Glenn T; Goetz, Christopher G

2009-04-15

Upper and lower gastrointestinal dysautonomia symptoms (GIDS)--sialorrhea, dysphagia, and constipation are common in Parkinson's disease (PD) and often socially as well as physically disabling for patients. Available invasive quantitative measures for assessing these symptoms and their response to therapy are time-consuming, require specialized equipment, can cause patient discomfort and present patients with risk. The Movement Disorders Society commissioned a task force to assess available clinical rating scales, critique their clinimetric properties, and make recommendations regarding their clinical utility. Six clinical researchers and a biostatistician systematically searched the literature for scales of sialorrhea, dysphagia, and constipation, evaluated the scales' previous use, performance parameters, and quality of validation data (if available). A scale was designated "Recommended" if the scale was used in clinical studies beyond the group that developed it, has been specifically used in PD reports, and clinimetric studies have established that it is a valid, reliable, and sensitive. "Suggested" scales met at least part of the above criteria, but fell short of meeting all. Based on the systematic review, scales for individual symptoms of sialorrhea, dysphagia, and constipation were identified along with three global scales that include these symptoms in the context of assessing dysautonomia or nonmotor symptoms. Three sialorrhea scales met criteria for Suggested: Drooling Severity and Frequency Scale (DSFS), Drooling Rating Scale, and Sialorrhea Clinical Scale for PD (SCS-PD). Two dysphagia scales, the Swallowing Disturbance Questionnaire (SDQ) and Dysphagia-Specific Quality of Life (SWAL-QOL), met criteria for Suggested. Although Rome III constipation module is widely accepted in the gastroenterology community, and the earlier version from the Rome II criteria has been used in a single study of PD patients, neither met criteria for Suggested or Recommended. Among the global scales, the Scales for Outcomes in PD-Autonomic (SCOPA-AUT) and Nonmotor Symptoms Questionnaire for PD (NMSQuest) both met criteria for Recommended, and the Nonmotor Symptoms Scale (NMSS) met criteria for Suggested; however, none specifically focuses on the target gastrointestinal symptoms (sialorrhea, dysphagia, and constipation) of this report. A very small number of rating scales have been applied to studies of gastrointestinal-related dysautonomia in PD. Only two scales met "Recommended" criteria and neither focuses specifically on the symptoms of sialorrhea, dysphagia, and constipation. Further scale testing in PD among the scales that focus on these symptoms is warranted, and no new scales are needed until the available scales are fully tested clinimetrically.

Measuring Response Styles Across the Big Five: A Multiscale Extension of an Approach Using Multinomial Processing Trees.

PubMed

Khorramdel, Lale; von Davier, Matthias

2014-01-01

This study shows how to address the problem of trait-unrelated response styles (RS) in rating scales using multidimensional item response theory. The aim is to test and correct data for RS in order to provide fair assessments of personality. Expanding on an approach presented by Böckenholt (2012), observed rating data are decomposed into multiple response processes based on a multinomial processing tree. The data come from a questionnaire consisting of 50 items of the International Personality Item Pool measuring the Big Five dimensions administered to 2,026 U.S. students with a 5-point rating scale. It is shown that this approach can be used to test if RS exist in the data and that RS can be differentiated from trait-related responses. Although the extreme RS appear to be unidimensional after exclusion of only 1 item, a unidimensional measure for the midpoint RS is obtained only after exclusion of 10 items. Both RS measurements show high cross-scale correlations and item response theory-based (marginal) reliabilities. Cultural differences could be found in giving extreme responses. Moreover, it is shown how to score rating data to correct for RS after being proved to exist in the data.

Behavioural problems and autism in children with hydrocephalus : a population-based study.

PubMed

Lindquist, Barbro; Carlsson, Göran; Persson, Eva-Karin; Uvebrant, Paul

2006-06-01

To investigate the prevalence of behavioural problems and autism in a population-based group of children with hydrocephalus and to see whether learning disabilities, cerebral palsy (CP), epilepsy, myelomeningocele (MMC) or preterm birth increase the risk of these problems. In the 107 children with hydrocephalus born in western Sweden in 1989-1993, behaviour was assessed using the Conners' parent rating scales in 66 and the teacher's rating scales in 57. Autism was investigated using the Childhood Autism Rating Scale. Parents rated 67% of the children and teachers 39% of the children as having behavioural problems (>1.5 SD, or T score >65). Learning disabilities increased the risk significantly and almost all the children with CP and/or epilepsy had behavioural problems. Autism was present in nine children (13%), in 20% of those without MMC and in one of 26 with MMC. Autism was significantly more frequent in children with learning disabilities (27% vs. 7%) and in children with CP and/or epilepsy (33% vs. 6%). The majority of children with hydrocephalus have behavioural problems and many have autism. It is therefore important to assess and understand all the aspects of cognition and behaviour in these children in order to minimise disability and enhance participation for the child.

Accretion of a New England (U.S.A.) salt march in response to inlet migration, storms, and sea-level rise

USGS Publications Warehouse

Roman, C.T.; Peck, J.A.; Allen, J.R.; King, J.W.; Appleby, P.G.

1997-01-01

Sediment accumulation rates were determined at several sites throughout Nauset Marsh (Massachusetts, U.S.A.), a back-barrier lagoonal system, using feldspar marker horizons to evaluate short-term rates (1 to 2 year scales) and radiometric techniques to estimate rates over longer time scales (137Cs, 210Pb, 14C). The barrier spit fronting the Spartina-dominated study site has a complex geomorphic history of inlet migration and over-wash events. This study evaluates sediment accumulation rates in relation to inlet migration, storm events, and sea-level rise. The marker horizon technique displayed strong temporal and spatial variability in response to storm events and proximity to the inlet. Sediment accumulation rates of up to 24 mm year -1 were recorded in the immediate vicinity of the inlet during a period that included several major coastal storms, while feldspar sites remote from the inlet had substantially lower rates (trace accumulation to 2.2 mm year -1). During storm-free periods, accumulation rates did not exceed 6.7 mm year -1, but remained quite variable among sites. Based on 137Cs (3.8 to 4.5 mm year -1) and 210Pb (2.6 to 4.2 mm year -1) radiometric techniques, integrating sediment accumulation over decadal time scales, the marsh appeared to be keeping pace with the relative rate of sealevel rise from 1921 to 1993 of 2.4 mm year -1. At one site, the 210Pb-based sedimentation rate and rate of relative sea-level rise were nearly similar and peat rhizome analysis revealed that Distichlis spicata recently replaced this once S.patens site, suggesting that this portion of Nauset Marsh may be getting wetter, thus representing an initial response to wetland submergence. Horizon markers are useful in evaluating the role of short-term events, such as storms or inlet migration, influencing marsh sedimentation processes. However, sampling methods that integrate marsh sedimentation over decadal time scales are preferable when evaluating a systems response to sea-level rise.

Accretion of a New England (U.S.A.) salt marsh in response to inlet migration, storms, and sea-level rise

USGS Publications Warehouse

Roman, C.T.; Peck, J.A.; Allen, J.R.; King, J.W.; Appleby, P.G.

1997-01-01

Sediment accumulation rates were determined at several sites throughout Nauset Marsh (Massachusetts, U.S.A.), a back-barrier lagoonal system, using feldspar marker horizons to evaluate short-term rates (1 to 2 year scales) and radiometric techniques to estimate rates over longer time scales (137Cs, 210Pb, 14C). The barrier spit fronting the Spartima-dominated study site has a complex geomorphic history of inlet migration and overwash events. This study evaluates sediment accumulation rates in relation to inlet migration, storm events and sea-level rise. The marker horizon technique displayed strong temporal and spatial variability in response to storm events and proximity to the inlet. Sediment accumulation rates of up to 24 mm year-1 were recorded in the immediate vicinity of the inlet during a period that included several major coastal storms, while feldspar sites remote from the inlet had substantially lower rates (trace accumulation to 2.2 mm year-1). During storm-free periods, accumulation rates did not exceed 6.7 mm year-1, but remained quite variable among sites. Based on 137Cs (3.8 to 4.5 mm year-1) and 210Pb (2.6 to 4.2 mm year-1) radiometric techniques, integrating sediment accumulation over decadal time scales, the marsh appeared to be keeping pace with the relative rate of sea-level rise from 1921 to 1993 of 2.4 mm year-1. At one site, the 210Pb-based sedimentation rate and rate of relative sea-level rise were nearly similar and peat rhizome analysis revealed that Distichlis spicata recently replaced this once S. patens site, suggesting that this portion of Nauset Marsh may be getting wetter, thus representing an initial response to wetland submergence. Horizon markers are useful in evaluating the role of short-term events, such as storms or inlet migration, influencing marsh sedimentation processes. However, sampling methods that integrate marsh sedimentation over decadal time scales are preferable when evaluating a systems response to sea-level rise.

Turbulence-assisted shear exfoliation of graphene using household detergent and a kitchen blender

NASA Astrophysics Data System (ADS)

Varrla, Eswaraiah; Paton, Keith R.; Backes, Claudia; Harvey, Andrew; Smith, Ronan J.; McCauley, Joe; Coleman, Jonathan N.

2014-09-01

To facilitate progression from the lab to commercial applications, it will be necessary to develop simple, scalable methods to produce high quality graphene. Here we demonstrate the production of large quantities of defect-free graphene using a kitchen blender and household detergent. We have characterised the scaling of both graphene concentration and production rate with the mixing parameters: mixing time, initial graphite concentration, rotor speed and liquid volume. We find the production rate to be invariant with mixing time and to increase strongly with mixing volume, results which are important for scale-up. Even in this simple system, concentrations of up to 1 mg ml-1 and graphene masses of >500 mg can be achieved after a few hours mixing. The maximum production rate was ~0.15 g h-1, much higher than for standard sonication-based exfoliation methods. We demonstrate that graphene production occurs because the mean turbulent shear rate in the blender exceeds the critical shear rate for exfoliation.To facilitate progression from the lab to commercial applications, it will be necessary to develop simple, scalable methods to produce high quality graphene. Here we demonstrate the production of large quantities of defect-free graphene using a kitchen blender and household detergent. We have characterised the scaling of both graphene concentration and production rate with the mixing parameters: mixing time, initial graphite concentration, rotor speed and liquid volume. We find the production rate to be invariant with mixing time and to increase strongly with mixing volume, results which are important for scale-up. Even in this simple system, concentrations of up to 1 mg ml-1 and graphene masses of >500 mg can be achieved after a few hours mixing. The maximum production rate was ~0.15 g h-1, much higher than for standard sonication-based exfoliation methods. We demonstrate that graphene production occurs because the mean turbulent shear rate in the blender exceeds the critical shear rate for exfoliation. Electronic supplementary information (ESI) available. See DOI: 10.1039/c4nr03560g

Measurement of Quality of Life II. From the Philosophy of Life to Science

PubMed Central

Ventegodt, Soren; Merrick, Joav; Andersen, Niels Jorgen

2003-01-01

We believe it should be possible to make operational the philosophical ideas of the good life in order to make it the object of scientific research. The Quality of Life Research Center in Copenhagen, Denmark has therefore spent the last several years with these questions and tried to find practical and evidence-based scientific solutions.This paper describes the theoretical road taken in moving from the abstract philosophy of life to the actual questionnaire. It presents an important aspect of our work with the quality-of-life (QOL) concept though the last decade. We have developed the quality-of-life philosophy; the SEQOL, QOL5, and QOL1 questionnaires; the quality-of-life theory; and the quality-of-life research methodology. We carried out quality-of-life population surveys and developed techniques for improving quality of life with the chronically sick patient. This paper presents the struggle to create a rating scale for the generic measurement of the global quality of life, based on quality-of-life theory, derived from quality-of-life philosophy. The developed rating scale is a ratio scale combining a Likert scale, a visual analogue scale, and a numerical scale, to a reduced combination scale. This allows for the extraction of as much information from the respondents as possible without exhausting them unduly or demanding more than can be reasonably expected. PMID:14570987

Measurement of quality of life II. From the philosophy of life to science.

PubMed

Ventegodt, Søren; Merrick, Joav; Andersen, Niels Jørgen

2003-10-13

We believe it should be possible to make operational the philosophical ideas of the good life in order to make it the object of scientific research. The Quality of Life Research Center in Copenhagen, Denmark has therefore spent the last several years with these questions and tried to find practical and evidence-based scientific solutions. This paper describes the theoretical road taken in moving from the abstract philosophy of life to the actual questionnaire. It presents an important aspect of our work with the quality-of-life (QOL) concept though the last decade. We have developed the quality-of-life philosophy; the SEQOL, QOL5, and QOL1 questionnaires; the quality-of-life theory; and the quality-of-life research methodology. We carried out quality-of-life population surveys and developed techniques for improving quality of life with the chronically sick patient. This paper presents the struggle to create a rating scale for the generic measurement of the global quality of life, based on quality-of-life theory, derived from quality-of-life philosophy. The developed rating scale is a ratio scale combining a Likert scale, a visual analogue scale, and a numerical scale, to a reduced combination scale. This allows for the extraction of as much information from the respondents as possible without exhausting them unduly or demanding more than can be reasonably expected.

Recovery and its correlates among patients with bipolar disorder: A study from a tertiary care centre in North India.

PubMed

Grover, Sandeep; Hazari, Nandita; Aneja, Jitender; Chakrabarti, Subho; Sharma, Sunil; Avasthi, Ajit

2016-12-01

The goal of treatment in mental illness has evolved from a symptom-based approach to a personal recovery-based approach. The aim of this study was to evaluate the predictors of personal recovery among patients with bipolar disorder. A total of 185 patients with bipolar disorder, currently in remission, were evaluated on Recovery Assessment Scale (RAS), Internalized Stigma of Mental Illness Scale (ISMIS), Brief Religious coping scale (RCOPE), Duke University Religiosity Index (DUREL), Religiousness Measures Scale, Hamilton depression rating scale (HDRS), Young Mania rating scale (YMRS) and Global Assessment of Functioning (GAF) scale. The mean age of the sample was 40.5 (standard deviation (SD), 11.26) years. Majority of the participants were male, married, working, Hindu by religion and belonged to extended/joint families of urban background. In the regression analysis, RAS scores were predicted significantly by discrimination experience, stereotype endorsement and alienation domains of ISMIS, level of functioning as assessed by GAF, residual depressive symptoms as assessed by HDRS and occupational status. The level of variance explained for total RAS score and various RAS domains ranged from 36.2% to 46.9%. This study suggests that personal recovery among patients with bipolar disorder is affected by stigma, level of functioning, residual depressive symptoms and employment status of patients with bipolar disorder. © The Author(s) 2016.

Utility of numerical and visual analog scales for evaluating the post-operative pain in rural patients

PubMed Central

Mudgalkar, Nikhil; Bele, Samir D; Valsangkar, Sameer; Bodhare, Trupti N; Gorre, Mahipal

2012-01-01

Background: Visual analog scales (VAS) and numeric analog scales (NAS) are used to assess post-operative pain, but few studies indicate their usefulness in rural illiterate population in India. Aims: This study was designed to 1) Compare the impact of literacy on the ability to indicate pain rating on VAS and NAS in post-operative rural patients. 2) Assess the level of agreement between the pain scales. Setting and Design: Cross sectional, hospital based study. Methods: Informed consent was obtained from patients prior to undergoing surgical procedures in a teaching hospital. Post surgery, patients who were conscious and coherent, were asked to rate pain on both VAS and NAS. The pain ratings were obtained within 24 hours of surgery and within 5 minutes of each other. Statistical Methods: Percentages, chi square test, regression analysis. Results: A total of 105 patients participated in the study. 43 (41%) of the sample was illiterate. 82 (78.1%) were able to rate pain on VAS while 81 (77.1%) were able to rate pain on NAS. There was no significant association between pain ratings and type of surgery, duration of surgery and nature of anaesthesia. In multivariate analysis, age, sex and literacy had no significant association with the ability to rate pain on VAS (P value 0.652, 0.967, 0.328 respectively). Similarly, no significant association was obtained between age, sex and literacy and ability to rate pain on NAS (P value 0.713, 0.405, 0.875 respectively). Correlation coefficient between the scales was 0.693. Conclusion: VAS and NAS can be used interchangeably in Indian rural population as post-operative pain assessment tools irrespective of literacy status. PMID:23325940

Utility of numerical and visual analog scales for evaluating the post-operative pain in rural patients.

PubMed

Mudgalkar, Nikhil; Bele, Samir D; Valsangkar, Sameer; Bodhare, Trupti N; Gorre, Mahipal

2012-11-01

Visual analog scales (VAS) and numeric analog scales (NAS) are used to assess post-operative pain, but few studies indicate their usefulness in rural illiterate population in India. This study was designed to 1) Compare the impact of literacy on the ability to indicate pain rating on VAS and NAS in post-operative rural patients. 2) Assess the level of agreement between the pain scales. Cross sectional, hospital based study. Informed consent was obtained from patients prior to undergoing surgical procedures in a teaching hospital. Post surgery, patients who were conscious and coherent, were asked to rate pain on both VAS and NAS. The pain ratings were obtained within 24 hours of surgery and within 5 minutes of each other. Percentages, chi square test, regression analysis. A total of 105 patients participated in the study. 43 (41%) of the sample was illiterate. 82 (78.1%) were able to rate pain on VAS while 81 (77.1%) were able to rate pain on NAS. There was no significant association between pain ratings and type of surgery, duration of surgery and nature of anaesthesia. In multivariate analysis, age, sex and literacy had no significant association with the ability to rate pain on VAS (P value 0.652, 0.967, 0.328 respectively). Similarly, no significant association was obtained between age, sex and literacy and ability to rate pain on NAS (P value 0.713, 0.405, 0.875 respectively). Correlation coefficient between the scales was 0.693. VAS and NAS can be used interchangeably in Indian rural population as post-operative pain assessment tools irrespective of literacy status.

Dysautonomia Rating Scales in Parkinson’s Disease: Sialorrhea, Dysphagia, and Constipation—Critique and Recommendations by Movement Disorders Task Force on Rating Scales for Parkinson’s Disease

PubMed Central

Evatt, Marian L.; Chaudhuri, K. Ray; Chou, Kelvin L.; Cubo, Ester; Hinson, Vanessa; Kompoliti, Katie; Yang, Chengwu; Poewe, Werner; Rascol, Olivier; Sampaio, Cristina; Stebbins, Glenn T.; Goetz, Christopher G.

2015-01-01

Upper and lower gastrointestinal dysautonomia symptoms (GIDS)—sialorrhea, dysphagia, and constipation are common in Parkinson’s disease (PD) and often socially as well as physically disabling for patients. Available invasive quantitative measures for assessing these symptoms and their response to therapy are time-consuming, require specialized equipment, can cause patient discomfort and present patients with risk. The Movement Disorders Society commissioned a task force to assess available clinical rating scales, critique their clinimetric properties, and make recommendations regarding their clinical utility. Six clinical researchers and a biostatistician systematically searched the literature for scales of sialorrhea, dysphagia, and constipation, evaluated the scales’ previous use, performance parameters, and quality of validation data (if available). A scale was designated “Recommended” if the scale was used in clinical studies beyond the group that developed it, has been specifically used in PD reports, and clinimetric studies have established that it is a valid, reliable, and sensitive. “Suggested” scales met at least part of the above criteria, but fell short of meeting all. Based on the systematic review, scales for individual symptoms of sialorrhea, dysphagia, and constipation were identified along with three global scales that include these symptoms in the context of assessing dysautonomia or nonmotor symptoms. Three sialorrhea scales met criteria for Suggested: Drooling Severity and Frequency Scale (DSFS), Drooling Rating Scale, and Sialorrhea Clinical Scale for PD (SCS-PD). Two dysphagia scales, the Swallowing Disturbance Questionnaire (SDQ) and Dysphagia-Specific Quality of Life (SWAL-QOL), met criteria for Suggested. Although Rome III constipation module is widely accepted in the gastroenterology community, and the earlier version from the Rome II criteria has been used in a single study of PD patients, neither met criteria for Suggested or Recommended. Among the global scales, the Scales for Outcomes in PD-Autonomic (SCOPA-AUT) and Nonmotor Symptoms Questionnaire for PD (NMSQuest) both met criteria for Recommended, and the Nonmotor Symptoms Scale (NMSS) met criteria for Suggested; however, none specifically focuses on the target gastrointestinal symptoms (sialorrhea, dysphagia, and constipation) of this report. A very small number of rating scales have been applied to studies of gastrointestinal-related dysautonomia in PD. Only two scales met “Recommended” criteria and neither focuses specifically on the symptoms of sialorrhea, dysphagia, and constipation. Further scale testing in PD among the scales that focus on these symptoms is warranted, and no new scales are needed until the available scales are fully tested clinimetrically. PMID:19205066

The Development and Validation of the Intercultural Sensitivity Scale.

ERIC Educational Resources Information Center

Chen, Guo-Ming; Starosta, William J.

The present study developed and assessed reliability and validity of a new instrument, the Intercultural Sensitivity Scale (ISS). Based on a review of the literature, 44 items thought to be important for intercultural sensitivity were generated. A sample of 414 college students rated these items and generated a 24-item final version of the…

Evaluating the Validity and Reliability of a Student Self-Advocacy Teacher Rating Scale

ERIC Educational Resources Information Center

Walick, Christopher M.

2017-01-01

Self-advocacy skills are critical to high school and post-secondary success. Unfortunately, students with disabilities often times struggle with self-advocacy. While there are effective, evidence-based programs to teach self-advocacy skills, there are few scales that directly measure self-advocacy. The current research study was conducted to…

Cavitation erosion prediction based on analysis of flow dynamics and impact load spectra

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mihatsch, Michael S., E-mail: michael.mihatsch@aer.mw.tum.de; Schmidt, Steffen J.; Adams, Nikolaus A.

2015-10-15

Cavitation erosion is the consequence of repeated collapse-induced high pressure-loads on a material surface. The present paper assesses the prediction of impact load spectra of cavitating flows, i.e., the rate and intensity distribution of collapse events based on a detailed analysis of flow dynamics. Data are obtained from a numerical simulation which employs a density-based finite volume method, taking into account the compressibility of both phases, and resolves collapse-induced pressure waves. To determine the spectrum of collapse events in the fluid domain, we detect and quantify the collapse of isolated vapor structures. As reference configuration we consider the expansion ofmore » a liquid into a radially divergent gap which exhibits unsteady sheet and cloud cavitation. Analysis of simulation data shows that global cavitation dynamics and dominant flow events are well resolved, even though the spatial resolution is too coarse to resolve individual vapor bubbles. The inviscid flow model recovers increasingly fine-scale vapor structures and collapses with increasing resolution. We demonstrate that frequency and intensity of these collapse events scale with grid resolution. Scaling laws based on two reference lengths are introduced for this purpose. We show that upon applying these laws impact load spectra recorded on experimental and numerical pressure sensors agree with each other. Furthermore, correlation between experimental pitting rates and collapse-event rates is found. Locations of high maximum wall pressures and high densities of collapse events near walls obtained numerically agree well with areas of erosion damage in the experiment. The investigation shows that impact load spectra of cavitating flows can be inferred from flow data that captures the main vapor structures and wave dynamics without the need for resolving all flow scales.« less

Multi-scale continuum modeling of biological processes: from molecular electro-diffusion to sub-cellular signaling transduction

NASA Astrophysics Data System (ADS)

Cheng, Y.; Kekenes-Huskey, P.; Hake, J. E.; Holst, M. J.; McCammon, J. A.; Michailova, A. P.

2012-01-01

This paper presents a brief review of multi-scale modeling at the molecular to cellular scale, with new results for heart muscle cells. A finite element-based simulation package (SMOL) was used to investigate the signaling transduction at molecular and sub-cellular scales (http://mccammon.ucsd.edu/smol/, http://FETK.org) by numerical solution of the time-dependent Smoluchowski equations and a reaction-diffusion system. At the molecular scale, SMOL has yielded experimentally validated estimates of the diffusion-limited association rates for the binding of acetylcholine to mouse acetylcholinesterase using crystallographic structural data. The predicted rate constants exhibit increasingly delayed steady-state times, with increasing ionic strength, and demonstrate the role of an enzyme's electrostatic potential in influencing ligand binding. At the sub-cellular scale, an extension of SMOL solves a nonlinear, reaction-diffusion system describing Ca2+ ligand buffering and diffusion in experimentally derived rodent ventricular myocyte geometries. Results reveal the important role of mobile and stationary Ca2+ buffers, including Ca2+ indicator dye. We found that alterations in Ca2+-binding and dissociation rates of troponin C (TnC) and total TnC concentration modulate sub-cellular Ca2+ signals. The model predicts that reduced off-rate in the whole troponin complex (TnC, TnI, TnT) versus reconstructed thin filaments (Tn, Tm, actin) alters cytosolic Ca2+ dynamics under control conditions or in disease-linked TnC mutations. The ultimate goal of these studies is to develop scalable methods and theories for the integration of molecular-scale information into simulations of cellular-scale systems.

On the resilience of helical magnetic fields to turbulent diffusion and the astrophysical implications

NASA Astrophysics Data System (ADS)

Blackman, Eric G.; Subramanian, Kandaswamy

2013-02-01

The extent to which large-scale magnetic fields are susceptible to turbulent diffusion is important for interpreting the need for in situ large-scale dynamos in astrophysics and for observationally inferring field strengths compared to kinetic energy. By solving coupled evolution equations for magnetic energy and magnetic helicity in a system initialized with isotropic turbulence and an arbitrarily helical large-scale field, we quantify the decay rate of the latter for a bounded or periodic system. The magnetic energy associated with the non-helical large-scale field decays at least as fast as the kinematically estimated turbulent diffusion rate, but the decay rate of the helical part depends on whether the ratio of its magnetic energy to the turbulent kinetic energy exceeds a critical value given by M1, c = (k1/k2)2, where k1 and k2 are the wavenumbers of the large and forcing scales. Turbulently diffusing helical fields to small scales while conserving magnetic helicity requires a rapid increase in total magnetic energy. As such, only when the helical field is subcritical can it so diffuse. When supercritical, it decays slowly, at a rate determined by microphysical dissipation even in the presence of macroscopic turbulence. In effect, turbulent diffusion of such a large-scale helical field produces small-scale helicity whose amplification abates further turbulent diffusion. Two curious implications are that (1) standard arguments supporting the need for in situ large-scale dynamos based on the otherwise rapid turbulent diffusion of large-scale fields require re-thinking since only the large-scale non-helical field is so diffused in a closed system. Boundary terms could however provide potential pathways for rapid change of the large-scale helical field. (2) Since M1, c ≪ 1 for k1 ≪ k2, the presence of long-lived ordered large-scale helical fields as in extragalactic jets do not guarantee that the magnetic field dominates the kinetic energy.

Estimated rates of groundwater recharge to the Chicot, Evangeline and Jasper aquifers by using environmental tracers in Montgomery and adjacent counties, Texas, 2008 and 2011

USGS Publications Warehouse

Oden, Timothy D.; Truini, Margot

2013-01-01

Recharge rates estimated from environmental tracer data are dependent upon several hydrogeologic variables and have inherent uncertainties. By using the recharge estimates derived from samples collected from 14 wells completed in the Chicot aquifer for which apparent groundwater ages could be determined, recharge to the Chicot aquifer ranged from 0.2 to 7.2 inches (in.) per year (yr). Based on data from one well, estimated recharge to the unconfined zone of the Evangeline aquifer (outcrop) was 0.1 in./yr. Based on data collected from eight wells, estimated rates of recharge to the confined zone of the Evangeline aquifer ranged from less than 0.1 to 2.8 in./yr. Based on data from one well, estimated recharge to the unconfined zone of the Jasper aquifer (outcrop) was 0.5 in./yr. Based on data collected from nine wells, estimated rates of recharge to the confined zone of the Jasper aquifer ranged from less than 0.1 to 0.1 in./yr. The complexity of the hydrogeology in the area, uncertainty in the conceptual model, and numerical assumptions required in the determination of the recharge rates all pose limitations and need to be considered when evaluating these data on a countywide or regional scale. The estimated recharge rates calculated for this study are specific to each well location and should not be extrapolated or inferred as a countywide average. Local variations in the hydrogeology and surficial conditions can affect the recharge rate at a local scale.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Manohar, AK; Yang, CG; Malkhandi, S

Iron-based alkaline rechargeable batteries have the potential of meeting the needs of large-scale electrical energy storage because of their low-cost, robustness and eco-friendliness. However, the widespread commercial deployment of iron-based batteries has been limited by the low charging efficiency and the poor discharge rate capability of the iron electrode. In this study, we have demonstrated iron electrodes containing bismuth oxide and iron sulfide with a charging efficiency of 92% and capable of being discharged at the 3C rate. Such a high value of charging efficiency combined with the ability to discharge at high rates is being reported for the firstmore » time. The bismuth oxide additive led to the in situ formation of elemental bismuth and a consequent increase in the overpotential for the hydrogen evolution reaction leading to an increase in the charging efficiency. We observed that the sulfide ions added to the electrolyte and iron sulfide added to the electrode mitigated-electrode passivation and allowed for continuous discharge at high rates. At the 3C discharge rate, a utilization of 0.2 Ah/g was achieved. The performance level of the rechargeable iron electrode demonstrated here is attractive for designing economically-viable large-scale energy storage systems based on alkaline nickel-iron and iron-air batteries. (C) 2013 The Electrochemical Society. All rights reserved.« less

Elucidating the impact of micro-scale heterogeneous bacterial distribution on biodegradation

NASA Astrophysics Data System (ADS)

Schmidt, Susanne I.; Kreft, Jan-Ulrich; Mackay, Rae; Picioreanu, Cristian; Thullner, Martin

2018-06-01

Groundwater microorganisms hardly ever cover the solid matrix uniformly-instead they form micro-scale colonies. To which extent such colony formation limits the bioavailability and biodegradation of a substrate is poorly understood. We used a high-resolution numerical model of a single pore channel inhabited by bacterial colonies to simulate the transport and biodegradation of organic substrates. These high-resolution 2D simulation results were compared to 1D simulations that were based on effective rate laws for bioavailability-limited biodegradation. We (i) quantified the observed bioavailability limitations and (ii) evaluated the applicability of previously established effective rate concepts if microorganisms are heterogeneously distributed. Effective bioavailability reductions of up to more than one order of magnitude were observed, showing that the micro-scale aggregation of bacterial cells into colonies can severely restrict the bioavailability of a substrate and reduce in situ degradation rates. Effective rate laws proved applicable for upscaling when using the introduced effective colony sizes.

The impact of failing to identify suspect effort in patients undergoing adult attention-deficit/hyperactivity disorder (ADHD) assessment.

PubMed

Marshall, Paul S; Hoelzle, James B; Heyerdahl, Danielle; Nelson, Nathaniel W

2016-10-01

[Correction Notice: An Erratum for this article was reported in Vol 28(10) of Psychological Assessment (see record 2016-22725-001). In the article, the penultimate sentence of the abstract should read “These results suggest that a significant percentage of those making a suspect effort will be diagnosed with ADHD using the most commonly employed assessment methods: an interview alone (71%); an interview and ADHD behavior rating scales combined (65%); and an interview, behavior rating scales, and most continuous performance tests combined (62%).” All versions of this article have been corrected.] This retrospective study examines how many adult patients would plausibly receive a diagnosis of attention-deficit/hyperactivity disorder (ADHD) if performance and symptom validity measures were not administered during neuropsychological evaluations. Five hundred fifty-four patients were extracted from an archival clinical dataset. A total of 102 were diagnosed with ADHD based on cognitive testing, behavior rating scales, effort testing, and clinical interview; 115 were identified as putting forth suspect effort in accordance with the Slick, Sherman, and Iverson (1999) criteria. From a clinical decision-making perspective, suspect effort and ADHD groups were nearly indistinguishable on ADHD behavior, executive function, and functional impairment rating scales, as well as on cognitive testing and key clinical interview questions. These results suggest that a significant percentage of those making a suspect effort will be diagnosed with ADHD using the most commonly employed assessment methods: an interview alone (71%); an interview and ADHD behavior rating scales combined (65%); and an interview, behavior rating scales, and most continuous performance tests combined (62%) [corrected]. This research makes clear that it is essential to evaluate task engagement and possible symptom amplification during clinical evaluations. PsycINFO Database Record (c) 2016 APA, all rights reserved

Microfluidics for producing poly (lactic-co-glycolic acid)-based pharmaceutical nanoparticles.

PubMed

Li, Xuanyu; Jiang, Xingyu

2017-12-24

Microfluidic chips allow the rapid production of a library of nanoparticles (NPs) with distinct properties by changing the precursors and the flow rates, significantly decreasing the time for screening optimal formulation as carriers for drug delivery compared to conventional methods. The batch-to-batch reproducibility which is essential for clinical translation is achieved by precisely controlling the precursors and the flow rate, regardless of operators. Poly (lactic-co-glycolic acid) (PLGA) is the most widely used Food and Drug Administration (FDA)-approved biodegradable polymers. Researchers often combine PLGA with lipids or amphiphilic molecules to assemble into a core/shell structure to exploit the potential of PLGA-based NPs as powerful carriers for cancer-related drug delivery. In this review, we discuss the advantages associated with microfluidic chips for producing PLGA-based functional nanocomplexes for drug delivery. These laboratory-based methods can readily scale up to provide sufficient amount of PLGA-based NPs in microfluidic chips for clinical studies and industrial-scale production. Copyright © 2017. Published by Elsevier B.V.

Inhomogeneous scaling behaviors in Malaysian foreign currency exchange rates

NASA Astrophysics Data System (ADS)

Muniandy, S. V.; Lim, S. C.; Murugan, R.

2001-12-01

In this paper, we investigate the fractal scaling behaviors of foreign currency exchange rates with respect to Malaysian currency, Ringgit Malaysia. These time series are examined piecewise before and after the currency control imposed in 1st September 1998 using the monofractal model based on fractional Brownian motion. The global Hurst exponents are determined using the R/ S analysis, the detrended fluctuation analysis and the method of second moment using the correlation coefficients. The limitation of these monofractal analyses is discussed. The usual multifractal analysis reveals that there exists a wide range of Hurst exponents in each of the time series. A new method of modelling the multifractal time series based on multifractional Brownian motion with time-varying Hurst exponents is studied.

Characterising Dynamic Instability in High Water-Cut Oil-Water Flows Using High-Resolution Microwave Sensor Signals

NASA Astrophysics Data System (ADS)

Liu, Weixin; Jin, Ningde; Han, Yunfeng; Ma, Jing

2018-06-01

In the present study, multi-scale entropy algorithm was used to characterise the complex flow phenomena of turbulent droplets in high water-cut oil-water two-phase flow. First, we compared multi-scale weighted permutation entropy (MWPE), multi-scale approximate entropy (MAE), multi-scale sample entropy (MSE) and multi-scale complexity measure (MCM) for typical nonlinear systems. The results show that MWPE presents satisfied variability with scale and anti-noise ability. Accordingly, we conducted an experiment of vertical upward oil-water two-phase flow with high water-cut and collected the signals of a high-resolution microwave resonant sensor, based on which two indexes, the entropy rate and mean value of MWPE, were extracted. Besides, the effects of total flow rate and water-cut on these two indexes were analysed. Our researches show that MWPE is an effective method to uncover the dynamic instability of oil-water two-phase flow with high water-cut.

Scaling of Precipitation Extremes Modelled by Generalized Pareto Distribution

NASA Astrophysics Data System (ADS)

Rajulapati, C. R.; Mujumdar, P. P.

2017-12-01

Precipitation extremes are often modelled with data from annual maximum series or peaks over threshold series. The Generalized Pareto Distribution (GPD) is commonly used to fit the peaks over threshold series. Scaling of precipitation extremes from larger time scales to smaller time scales when the extremes are modelled with the GPD is burdened with difficulties arising from varying thresholds for different durations. In this study, the scale invariance theory is used to develop a disaggregation model for precipitation extremes exceeding specified thresholds. A scaling relationship is developed for a range of thresholds obtained from a set of quantiles of non-zero precipitation of different durations. The GPD parameters and exceedance rate parameters are modelled by the Bayesian approach and the uncertainty in scaling exponent is quantified. A quantile based modification in the scaling relationship is proposed for obtaining the varying thresholds and exceedance rate parameters for shorter durations. The disaggregation model is applied to precipitation datasets of Berlin City, Germany and Bangalore City, India. From both the applications, it is observed that the uncertainty in the scaling exponent has a considerable effect on uncertainty in scaled parameters and return levels of shorter durations.

The effects of a home-based arm ergometry exercise programme on physical fitness, fatigue and activity in Polio survivors: a randomised controlled trial.

PubMed

Murray, D; Hardiman, O; Campion, A; Vance, R; Horgan, F; Meldrum, D

2017-07-01

To investigate the effect of an eight-week home-based arm ergometry aerobic exercise programme on physical fitness, fatigue, activity and quality of life in Polio Survivors. An assessor blinded randomised controlled trial. Home-based exercise. Fifty-five Polio survivors randomised to exercise or control groups. Home-based arm ergometry at an intensity of 50%-70% maximum heart rate, compared with usual physiotherapy care. The Six-minute Arm Test, Fatigue Severity Scale, Physical Activity Scale for Individuals with Physical Disabilities and SF-36. Assessments were completed at baseline and at eight weeks. There was no significant difference in the primary outcome, exercising heart rate during the Six-minute Arm Test, between the groups at follow-up [97.6 (SD10.1) compared to 102.4 (SD13.7) beats per minute ( P=0.20)]. Blood pressure was significantly lower in the intervention group at follow-up [systolic blood pressure 132(18.6)mmHg compared to 144.1(14.6)mmHg ( P=0.002)]. There were no between group differences in the Fatigue Severity Scale ( P=0.25) or Physical Activity Scale for Individuals with Physical Disabilities ( P=0.49), with a small difference in SF-36 physical component score ( P=0.04). This home-based arm ergometry programme successfully facilitated aerobic exercise in Polio Survivors, but did not result in a significant change in physical fitness, measured by the Six-minute Arm Test.

Assessing students' communication skills: validation of a global rating.

PubMed

Scheffer, Simone; Muehlinghaus, Isabel; Froehmel, Annette; Ortwein, Heiderose

2008-12-01

Communication skills training is an accepted part of undergraduate medical programs nowadays. In addition to learning experiences its importance should be emphasised by performance-based assessment. As detailed checklists have been shown to be not well suited for the assessment of communication skills for different reasons, this study aimed to validate a global rating scale. A Canadian instrument was translated to German and adapted to assess students' communication skills during an end-of-semester-OSCE. Subjects were second and third year medical students at the reformed track of the Charité-Universitaetsmedizin Berlin. Different groups of raters were trained to assess students' communication skills using the global rating scale. Validity testing included concurrent validity and construct validity: Judgements of different groups of raters were compared to expert ratings as a defined gold standard. Furthermore, the amount of agreement between scores obtained with this global rating scale and a different instrument for assessing communication skills was determined. Results show that communication skills can be validly assessed by trained non-expert raters as well as standardised patients using this instrument.

Hybrid fuel formulation and technology development

NASA Technical Reports Server (NTRS)

Dean, D. L.

1995-01-01

The objective was to develop an improved hybrid fuel with higher regression rate, a regression rate expression exponent close to 0.5, lower cost, and higher density. The approach was to formulate candidate fuels based on promising concepts, perform thermomechanical analyses to select the most promising candidates, develop laboratory processes to fabricate fuel grains as needed, fabricate fuel grains and test in a small lab-scale motor, select the best candidate, and then scale up and validate performance in a 2500 lbf scale, 11-inch diameter motor. The characteristics of a high performance fuel have been verified in 11-inch motor testing. The advanced fuel exhibits a 15% increase in density over an all hydrocarbon formulation accompanied by a 50% increase in regression rate, which when multiplied by the increase in density yields a 70% increase in fuel mass flow rate; has a significantly lower oxidizer-to-fuel (O/F) ratio requirement at 1.5; has a significantly decreased axial regression rate variation making for more uniform propellant flow throughout motor operation; is very clean burning; extinguishes cleanly and quickly; and burns with a high combustion efficiency.

Attachment-Based Family Therapy: "Adherence" and Differentiation

ERIC Educational Resources Information Center

Diamond, Gary M.; Diamond, Guy S.; Hogue, Aaron

2007-01-01

This study examined the fidelity of attachment-based family therapy (ABFT) for depressed adolescents. Trained observers used the therapist behavior rating scale (3rd version) to code therapist behaviors in 45 sessions of ABFT and 45 sessions each from two empirically based treatments for adolescent substance abusers: multidimensional family…

Facing the scaling problem: A multi-methodical approach to simulate soil erosion at hillslope and catchment scale

NASA Astrophysics Data System (ADS)

Schmengler, A. C.; Vlek, P. L. G.

2012-04-01

Modelling soil erosion requires a holistic understanding of the sediment dynamics in a complex environment. As most erosion models are scale-dependent and their parameterization is spatially limited, their application often requires special care, particularly in data-scarce environments. This study presents a hierarchical approach to overcome the limitations of a single model by using various quantitative methods and soil erosion models to cope with the issues of scale. At hillslope scale, the physically-based Water Erosion Prediction Project (WEPP)-model is used to simulate soil loss and deposition processes. Model simulations of soil loss vary between 5 to 50 t ha-1 yr-1 dependent on the spatial location on the hillslope and have only limited correspondence with the results of the 137Cs technique. These differences in absolute soil loss values could be either due to internal shortcomings of each approach or to external scale-related uncertainties. Pedo-geomorphological soil investigations along a catena confirm that estimations by the 137Cs technique are more appropriate in reflecting both the spatial extent and magnitude of soil erosion at hillslope scale. In order to account for sediment dynamics at a larger scale, the spatially-distributed WaTEM/SEDEM model is used to simulate soil erosion at catchment scale and to predict sediment delivery rates into a small water reservoir. Predicted sediment yield rates are compared with results gained from a bathymetric survey and sediment core analysis. Results show that specific sediment rates of 0.6 t ha-1 yr-1 by the model are in close agreement with observed sediment yield calculated from stratigraphical changes and downcore variations in 137Cs concentrations. Sediment erosion rates averaged over the entire catchment of 1 to 2 t ha-1 yr-1 are significantly lower than results obtained at hillslope scale confirming an inverse correlation between the magnitude of erosion rates and the spatial scale of the model. The study has shown that the use of multiple methods facilitates the calibration and validation of models and might provide a more accurate measure for soil erosion rates in ungauged catchments. Moreover, the approach could be used to identify the most appropriate working and operational scales for soil erosion modelling.

Relationships of leaf dark respiration to leaf nitrogen, specific leaf area and leaf life-span: a test across biomes and functional groups

Treesearch

Peter B. Reich; Michael B. Walters; David S. Ellsworth; [and others; [Editor’s note: James M.. Vose is the SRS co-author for this publication.

1998-01-01

Based on prior evidence of coordinated multiple leaf trait scaling, the authors hypothesized that variation among species in leaf dark respiration rate (Rd) should scale with variation in traits such as leaf nitrogen (N), leaf life-span, specific leaf area (SLA), and net photosynthetic capacity (Amax). However, it is not known whether such scaling, if it exists, is...

Direct coupling of a genome-scale microbial in silico model and a groundwater reactive transport model.

PubMed

Fang, Yilin; Scheibe, Timothy D; Mahadevan, Radhakrishnan; Garg, Srinath; Long, Philip E; Lovley, Derek R

2011-03-25

The activity of microorganisms often plays an important role in dynamic natural attenuation or engineered bioremediation of subsurface contaminants, such as chlorinated solvents, metals, and radionuclides. To evaluate and/or design bioremediated systems, quantitative reactive transport models are needed. State-of-the-art reactive transport models often ignore the microbial effects or simulate the microbial effects with static growth yield and constant reaction rate parameters over simulated conditions, while in reality microorganisms can dynamically modify their functionality (such as utilization of alternative respiratory pathways) in response to spatial and temporal variations in environmental conditions. Constraint-based genome-scale microbial in silico models, using genomic data and multiple-pathway reaction networks, have been shown to be able to simulate transient metabolism of some well studied microorganisms and identify growth rate, substrate uptake rates, and byproduct rates under different growth conditions. These rates can be identified and used to replace specific microbially-mediated reaction rates in a reactive transport model using local geochemical conditions as constraints. We previously demonstrated the potential utility of integrating a constraint-based microbial metabolism model with a reactive transport simulator as applied to bioremediation of uranium in groundwater. However, that work relied on an indirect coupling approach that was effective for initial demonstration but may not be extensible to more complex problems that are of significant interest (e.g., communities of microbial species and multiple constraining variables). Here, we extend that work by presenting and demonstrating a method of directly integrating a reactive transport model (FORTRAN code) with constraint-based in silico models solved with IBM ILOG CPLEX linear optimizer base system (C library). The models were integrated with BABEL, a language interoperability tool. The modeling system is designed in such a way that constraint-based models targeting different microorganisms or competing organism communities can be easily plugged into the system. Constraint-based modeling is very costly given the size of a genome-scale reaction network. To save computation time, a binary tree is traversed to examine the concentration and solution pool generated during the simulation in order to decide whether the constraint-based model should be called. We also show preliminary results from the integrated model including a comparison of the direct and indirect coupling approaches and evaluated the ability of the approach to simulate field experiment. Published by Elsevier B.V.

Competency-Based Medical Education: Can Both Junior Residents and Senior Residents Achieve Competence After a Sports Medicine Training Module?

PubMed

Dwyer, Tim; Wright, Sara; Kulasegaram, Kulamakan M; Theodoropoulos, John; Chahal, Jaskarndip; Wasserstein, David; Ringsted, Charlotte; Hodges, Brian; Ogilvie-Harris, Darrell

2015-12-02

Competency-based medical education as a resident-training format will move postgraduate training away from time-based training, to a model based on observable outcomes. The purpose of this study was to determine whether junior residents and senior residents could demonstrate clinical skills to a similar level, after a sports medicine rotation. All residents undertaking a three-month sports medicine rotation had to pass an Objective Structured Clinical Examination. The stations tested the fundamentals of history-taking, examination, image interpretation, differential diagnosis, informed consent, and clinical decision-making. Performance at each station was assessed with a binary station-specific checklist and an overall global rating scale, in which 1 indicated novice, 2 indicated advanced beginner, 3 indicated competent, 4 indicated proficient, and 5 indicated expert. A global rating scale was also given for each domain of knowledge. Over eighteen months, thirty-nine residents (twenty-one junior residents and eighteen senior residents) and six fellows (for a total of forty-five participants) completed the examination. With regard to junior residents and senior residents, analysis using a two-tailed t test demonstrated a significant difference (p < 0.01) in both total checklist score and overall global rating scale; the mean total checklist score (and standard deviation) was 56.15% ± 10.99% for junior residents and 71.87% ± 8.94% for senior residents, and the mean global rating scale was 2.44 ± 0.55 for junior residents and 3.79 ± 0.49 for senior residents. There was a significant difference between junior residents and senior residents for each knowledge domain, with a significance of p < 0.05 for history-taking and p < 0.01 for the remainder of the domains. Despite intensive teaching within a competency-based medical education model, junior residents were not able to demonstrate knowledge as well as senior residents, suggesting that overall clinical experience is critically important for achieving competency as measured by the Objective Structured Clinical Examination. Copyright © 2015 by The Journal of Bone and Joint Surgery, Incorporated.

Upscaling of nanoparticle transport in porous media under unfavorable conditions: Pore scale to Darcy scale

NASA Astrophysics Data System (ADS)

Seetha, N.; Raoof, Amir; Mohan Kumar, M. S.; Majid Hassanizadeh, S.

2017-05-01

Transport and deposition of nanoparticles in porous media is a multi-scale problem governed by several pore-scale processes, and hence, it is critical to link the processes at pore scale to the Darcy-scale behavior. In this study, using pore network modeling, we develop correlation equations for deposition rate coefficients for nanoparticle transport under unfavorable conditions at the Darcy scale based on pore-scale mechanisms. The upscaling tool is a multi-directional pore-network model consisting of an interconnected network of pores with variable connectivities. Correlation equations describing the pore-averaged deposition rate coefficients under unfavorable conditions in a cylindrical pore, developed in our earlier studies, are employed for each pore element. Pore-network simulations are performed for a wide range of parameter values to obtain the breakthrough curves of nanoparticle concentration. The latter is fitted with macroscopic 1-D advection-dispersion equation with a two-site linear reversible deposition accounting for both equilibrium and kinetic sorption. This leads to the estimation of three Darcy-scale deposition coefficients: distribution coefficient, kinetic rate constant, and the fraction of equilibrium sites. The correlation equations for the Darcy-scale deposition coefficients, under unfavorable conditions, are provided as a function of measurable Darcy-scale parameters, including: porosity, mean pore throat radius, mean pore water velocity, nanoparticle radius, ionic strength, dielectric constant, viscosity, temperature, and surface potentials of the particle and grain surfaces. The correlation equations are found to be consistent with the available experimental results, and in qualitative agreement with Colloid Filtration Theory for all parameters, except for the mean pore water velocity and nanoparticle radius.

Automated Decomposition of Model-based Learning Problems

NASA Technical Reports Server (NTRS)

Williams, Brian C.; Millar, Bill

1996-01-01

A new generation of sensor rich, massively distributed autonomous systems is being developed that has the potential for unprecedented performance, such as smart buildings, reconfigurable factories, adaptive traffic systems and remote earth ecosystem monitoring. To achieve high performance these massive systems will need to accurately model themselves and their environment from sensor information. Accomplishing this on a grand scale requires automating the art of large-scale modeling. This paper presents a formalization of [\\em decompositional model-based learning (DML)], a method developed by observing a modeler's expertise at decomposing large scale model estimation tasks. The method exploits a striking analogy between learning and consistency-based diagnosis. Moriarty, an implementation of DML, has been applied to thermal modeling of a smart building, demonstrating a significant improvement in learning rate.

The Microphysical Structure of Extreme Precipitation as Inferred from Ground-Based Raindrop Spectra.

NASA Astrophysics Data System (ADS)

Uijlenhoet, Remko; Smith, James A.; Steiner, Matthias

2003-05-01

The controls on the variability of raindrop size distributions in extreme rainfall and the associated radar reflectivity-rain rate relationships are studied using a scaling-law formalism for the description of raindrop size distributions and their properties. This scaling-law formalism enables a separation of the effects of changes in the scale of the raindrop size distribution from those in its shape. Parameters controlling the scale and shape of the scaled raindrop size distribution may be related to the microphysical processes generating extreme rainfall. A global scaling analysis of raindrop size distributions corresponding to rain rates exceeding 100 mm h1, collected during the 1950s with the Illinois State Water Survey raindrop camera in Miami, Florida, reveals that extreme rain rates tend to be associated with conditions in which the variability of the raindrop size distribution is strongly number controlled (i.e., characteristic drop sizes are roughly constant). This means that changes in properties of raindrop size distributions in extreme rainfall are largely produced by varying raindrop concentrations. As a result, rainfall integral variables (such as radar reflectivity and rain rate) are roughly proportional to each other, which is consistent with the concept of the so-called equilibrium raindrop size distribution and has profound implications for radar measurement of extreme rainfall. A time series analysis for two contrasting extreme rainfall events supports the hypothesis that the variability of raindrop size distributions for extreme rain rates is strongly number controlled. However, this analysis also reveals that the actual shapes of the (measured and scaled) spectra may differ significantly from storm to storm. This implies that the exponents of power-law radar reflectivity-rain rate relationships may be similar, and close to unity, for different extreme rainfall events, but their prefactors may differ substantially. Consequently, there is no unique radar reflectivity-rain rate relationship for extreme rain rates, but the variability is essentially reduced to one free parameter (i.e., the prefactor). It is suggested that this free parameter may be estimated on the basis of differential reflectivity measurements in extreme rainfall.

a Region-Based Multi-Scale Approach for Object-Based Image Analysis

NASA Astrophysics Data System (ADS)

Kavzoglu, T.; Yildiz Erdemir, M.; Tonbul, H.

2016-06-01

Within the last two decades, object-based image analysis (OBIA) considering objects (i.e. groups of pixels) instead of pixels has gained popularity and attracted increasing interest. The most important stage of the OBIA is image segmentation that groups spectrally similar adjacent pixels considering not only the spectral features but also spatial and textural features. Although there are several parameters (scale, shape, compactness and band weights) to be set by the analyst, scale parameter stands out the most important parameter in segmentation process. Estimating optimal scale parameter is crucially important to increase the classification accuracy that depends on image resolution, image object size and characteristics of the study area. In this study, two scale-selection strategies were implemented in the image segmentation process using pan-sharped Qickbird-2 image. The first strategy estimates optimal scale parameters for the eight sub-regions. For this purpose, the local variance/rate of change (LV-RoC) graphs produced by the ESP-2 tool were analysed to determine fine, moderate and coarse scales for each region. In the second strategy, the image was segmented using the three candidate scale values (fine, moderate, coarse) determined from the LV-RoC graph calculated for whole image. The nearest neighbour classifier was applied in all segmentation experiments and equal number of pixels was randomly selected to calculate accuracy metrics (overall accuracy and kappa coefficient). Comparison of region-based and image-based segmentation was carried out on the classified images and found that region-based multi-scale OBIA produced significantly more accurate results than image-based single-scale OBIA. The difference in classification accuracy reached to 10% in terms of overall accuracy.

Estimating Skin Cancer Risk: Evaluating Mobile Computer-Adaptive Testing.

PubMed

Djaja, Ngadiman; Janda, Monika; Olsen, Catherine M; Whiteman, David C; Chien, Tsair-Wei

2016-01-22

Response burden is a major detriment to questionnaire completion rates. Computer adaptive testing may offer advantages over non-adaptive testing, including reduction of numbers of items required for precise measurement. Our aim was to compare the efficiency of non-adaptive (NAT) and computer adaptive testing (CAT) facilitated by Partial Credit Model (PCM)-derived calibration to estimate skin cancer risk. We used a random sample from a population-based Australian cohort study of skin cancer risk (N=43,794). All 30 items of the skin cancer risk scale were calibrated with the Rasch PCM. A total of 1000 cases generated following a normal distribution (mean [SD] 0 [1]) were simulated using three Rasch models with three fixed-item (dichotomous, rating scale, and partial credit) scenarios, respectively. We calculated the comparative efficiency and precision of CAT and NAT (shortening of questionnaire length and the count difference number ratio less than 5% using independent t tests). We found that use of CAT led to smaller person standard error of the estimated measure than NAT, with substantially higher efficiency but no loss of precision, reducing response burden by 48%, 66%, and 66% for dichotomous, Rating Scale Model, and PCM models, respectively. CAT-based administrations of the skin cancer risk scale could substantially reduce participant burden without compromising measurement precision. A mobile computer adaptive test was developed to help people efficiently assess their skin cancer risk.

Generating Broad-Scale Forest Ownership Maps: A Closest-Neighbor Approach

Treesearch

Brett J. Butler

2005-01-01

A closest-neighbor method for producing a forest ownership map using remotely sensed imagery and point-based ownership information is presented for the Northeastern United States. Based on a validation data set, this method had an accuracy rate of 58 percent.

Forecasting of magnitude and duration of currency crises based on the analysis of distortions of fractal scaling in exchange rate fluctuations

NASA Astrophysics Data System (ADS)

Uritskaya, Olga Y.

2005-05-01

Results of fractal stability analysis of daily exchange rate fluctuations of more than 30 floating currencies for a 10-year period are presented. It is shown for the first time that small- and large-scale dynamical instabilities of national monetary systems correlate with deviations of the detrended fluctuation analysis (DFA) exponent from the value 1.5 predicted by the efficient market hypothesis. The observed dependence is used for classification of long-term stability of floating exchange rates as well as for revealing various forms of distortion of stable currency dynamics prior to large-scale crises. A normal range of DFA exponents consistent with crisis-free long-term exchange rate fluctuations is determined, and several typical scenarios of unstable currency dynamics with DFA exponents fluctuating beyond the normal range are identified. It is shown that monetary crashes are usually preceded by prolonged periods of abnormal (decreased or increased) DFA exponent, with the after-crash exponent tending to the value 1.5 indicating a more reliable exchange rate dynamics. Statistically significant regression relations (R=0.99, p<0.01) between duration and magnitude of currency crises and the degree of distortion of monofractal patterns of exchange rate dynamics are found. It is demonstrated that the parameters of these relations characterizing small- and large-scale crises are nearly equal, which implies a common instability mechanism underlying these events. The obtained dependences have been used as a basic ingredient of a forecasting technique which provided correct in-sample predictions of monetary crisis magnitude and duration over various time scales. The developed technique can be recommended for real-time monitoring of dynamical stability of floating exchange rate systems and creating advanced early-warning-system models for currency crisis prevention.

Classroom Contexts as the Framework for Assessing Social-Emotional Adjustment: A National Study in Trinidad and Tobago

ERIC Educational Resources Information Center

Mcdermott, Paul A.; Watkins, Marley W.; Drogalis, Anna Rhoad; Chao, Jessica L.; Worrell, Frank C.; Hall, Tracey E.

2016-01-01

Contextually based assessments reveal the circumstances accompanying maladjustment (the when, where, and with whom) and supply clues to the motivations underpinning problem behaviors. The Adjustment Scales for Children and Adolescents (ASCA) is a teacher rating scale composed of indicators describing behavior in 24 classroom situational contexts.…

A Social-Cognitive Intervention Program for Adolescents with Autism: A Pilot Study

ERIC Educational Resources Information Center

Cheung, Pui Pui Phoebe; Siu, Andrew M. H.; Brown, Ted; Yu, Mong-lin

2018-01-01

This pilot study explored the efficacy of a social-cognitive intervention program for adolescents with Autism Spectrum Disorder (ASD). Seven adolescents with ASD (mean age = 12.57 years) attended a school-based 10-week program. Social Skills Improvement System Rating Scales, Goal Attainment Scaling (GAS), and Theory of Mind Inventory were…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rizzi, Silvio; Hereld, Mark; Insley, Joseph

In this work we perform in-situ visualization of molecular dynamics simulations, which can help scientists to visualize simulation output on-the-fly, without incurring storage overheads. We present a case study to couple LAMMPS, the large-scale molecular dynamics simulation code with vl3, our parallel framework for large-scale visualization and analysis. Our motivation is to identify effective approaches for covisualization and exploration of large-scale atomistic simulations at interactive frame rates.We propose a system of coupled libraries and describe its architecture, with an implementation that runs on GPU-based clusters. We present the results of strong and weak scalability experiments, as well as future researchmore » avenues based on our results.« less

Indirect scaling methods for testing quantitative emotion theories.

PubMed

Junge, Martin; Reisenzein, Rainer

2013-01-01

Two studies investigated the utility of indirect scaling methods, based on graded pair comparisons, for the testing of quantitative emotion theories. In Study 1, we measured the intensity of relief and disappointment caused by lottery outcomes, and in Study 2, the intensity of disgust evoked by pictures, using both direct intensity ratings and graded pair comparisons. The stimuli were systematically constructed to reflect variables expected to influence the intensity of the emotions according to theoretical models of relief/disappointment and disgust, respectively. Two probabilistic scaling methods were used to estimate scale values from the pair comparison judgements: Additive functional measurement (AFM) and maximum likelihood difference scaling (MLDS). The emotion models were fitted to the direct and indirect intensity measurements using nonlinear regression (Study 1) and analysis of variance (Study 2). Both studies found substantially improved fits of the emotion models for the indirectly determined emotion intensities, with their advantage being evident particularly at the level of individual participants. The results suggest that indirect scaling methods yield more precise measurements of emotion intensity than rating scales and thereby provide stronger tests of emotion theories in general and quantitative emotion theories in particular.

Outcome Rating Scale and Session Rating Scale in Psychological Practice: Clinical Utility of Ultra-Brief Measures

ERIC Educational Resources Information Center

Campbell, Alistair; Hemsley, Samantha

2009-01-01

The validity and reliability of the Outcome Rating Scale (ORS) and the Session Rating Scale (SRS) were evaluated against existing longer measures, including the Outcome Questionnaire-45, Working Alliance Inventory, Depression Anxiety Stress Scale-21, Quality of Life Scale, Rosenberg Self-Esteem Scale and General Self-efficacy Scale. The measures…

Oxidation of alloys for energy applications in supercritical CO 2 and H 2O

DOE PAGES

Holcomb, Gordon R.; Carney, Casey; Doğan, Ömer N.

2016-03-19

To facilitate development of supercritical CO 2 (sCO 2) power plants, a comparison of the oxidation behavior of austenitic stainless steels and Ni-base alloys in sH 2O and sCO 2 were made. Experiments were conducted at 730 °C/207 bar (sCO 2) and 726 °C/208 bar (sH 2O). Ni-base alloys in sCO 2 did not exhibit much change with pressure. Ni-base alloys in sH 2O had an increase in corrosion rate and the log of the parabolic rate constant was proportional to pressure. Lastly, fine-grain austenitic stainless steels in sCO 2 and sH 2O were both less protective with pressure asmore » the dense protective chromia scale was replaced with faster growing Fe-oxide rich scales.« less

A Measure of Team Resilience: Developing the Resilience at Work Team Scale.

PubMed

McEwen, Kathryn; Boyd, Carolyn M

2018-03-01

This study develops, and initial evaluates, a new measure of team-based resilience for use in research and practice. We conducted preliminary analyses, based on a cross-sectional sample of 344 employees nested within 31 teams. Seven dimensions were identified through exploratory and confirmatory factor analyses. The measure had high reliability and significant discrimination to indicate the presence of a unique team-based aspect of resilience that contributed to higher work engagement and higher self-rated team performance, over and above the effects of individual resilience. Multilevel analyses showed that team, but not individual, resilience predicted self-rated team performance. Practice implications include a need to focus on collective as well as individual behaviors in resilience-building. The measure provides a diagnostic instrument for teams and a scale to evaluate organizational interventions and research the relationship of resilience to other constructs.

Development and verification of child observation sheet for 5-year-old children.

PubMed

Fujimoto, Keiko; Nagai, Toshisaburo; Okazaki, Shin; Kawajiri, Mie; Tomiwa, Kiyotaka

2014-02-01

The aim of the study was to develop a newly devised child observation sheet (COS-5) as a scoring sheet, based on the Childhood Autism Rating Scale (CARS), for use in the developmental evaluation of 5-year-old children, especially focusing on children with autistic features, and to verify its validity. Seventy-six children were studied. The children were recruited among participants of the Japan Children's Cohort Study, a research program implemented by the Research Institute of Science and Technology for Society (RISTEX) from 2004 to 2009. The developmental evaluation procedure was performed by doctors, clinical psychologists, and public health nurses. The COS-5 was also partly based on the Kyoto Scale of Psychological Development 2001 (Kyoto Scale 2001). Further, the Developmental Disorders Screening Questionnaire for 5-Years-Olds, PDD-Autism Society Japan Rating Scale (PARS), doctor interview questions and neurological examination for 5-year-old children, and the Draw-a-Man Test (DAM) were used as evaluation scales. Eighteen (25.4%) children were rated as Suspected, including Suspected PDD, Suspected ADHD and Suspected MR. The COS-5 was suggested to be valid with favorable reliability (α=0.89) and correlation with other evaluation scales. The COS-5 may be useful, with the following advantages: it can be performed within a shorter time frame; it facilitates the maintenance of observation quality; it facilitates sharing information with other professions; and it is reliable to identify the autistic features of 5-year-old children. In order to verify its wider applications including the screening of infants (18months to 3years old) by adjusting the items of younger age, additional study is needed. Copyright © 2013 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

Rates and time scales of clay-mineral formation by weathering in saprolitic regoliths of the southern Appalachians from geochemical mass balance

Treesearch

Jason R. Price; Michael A. Velbel; Lina C. Patino

2005-01-01

Rates of clay formation in three watersheds located at the Coweeta Hydrologic Laboratory, western North Carolina, have been determined from solute flux-based mass balance methods. A system of mass balance equations with enough equations and unknowns to allow calculation of secondary mineral formation rates as well as the more commonly determined primary-...

Validation of a scale for network therapy: a technique for systematic use of peer and family support in addition treatment.

PubMed

Keller, D S; Galanter, M; Weinberg, S

1997-02-01

Substance abuse treatments are increasingly employing standardized formats. This is especially the case for approaches that utilize an individual psychotherapy format but less so for family-based approaches. Network therapy, an approach that involves family members and peers in the patient's relapse prevention efforts, is theoretically and clinically differentiated in this paper from family systems therapy for addiction. Based on these conceptual differences, a Network Therapy Rating Scale (NTRS) was developed to measure the integrity and differentiability of network therapy from other family-based approaches to addiction treatment. Seven addictions faculty and 10 third- and fourth-year psychiatry residents recently trained in the network approach used the NTRS to rate excerpts of network and family systems therapy sessions. Data revealed the NTRS had high internal consistency reliability when utilized by both groups of raters. In addition, network and nonnetwork subscales within the NTRS rated congruent therapy excerpts significantly higher than noncongruent therapy excerpts, indicating that the NTRS subscales measure what they are designed to measure. Implications for research and training are discussed.

Dystonia rating scales: critique and recommendations

PubMed Central

Albanese, Alberto; Sorbo, Francesca Del; Comella, Cynthia; Jinnah, H.A.; Mink, Jonathan W.; Post, Bart; Vidailhet, Marie; Volkmann, Jens; Warner, Thomas T.; Leentjens, Albert F.G.; Martinez-Martin, Pablo; Stebbins, Glenn T.; Goetz, Christopher G.; Schrag, Anette

2014-01-01

Background Many rating scales have been applied to the evaluation of dystonia, but only few have been assessed for clinimetric properties. The Movement Disorders Society commissioned this task force to critique existing dystonia rating scales and place them in the clinical and clinimetric context. Methods A systematic literature review was conducted to identify rating scales that have either been validated or used in dystonia. Results Thirty six potential scales were identified. Eight were excluded because they did not meet review criteria, leaving twenty-eight scales that were critiqued and rated by the task force. Seven scales were found to meet criteria to be “recommended”: the Blepharospasm Disability Index is recommended for rating blepharospasm; the Cervical Dystonia Impact Scale and the Toronto Western Spasmodic Torticollis Rating Scale for rating cervical dystonia; the Craniocervical Dystonia Questionnaire for blepharospasm and cervical dystonia; the Voice Handicap Index (VHI) and the Vocal Performance Questionnaire (VPQ) for laryngeal dystonia; and the Fahn-Marsden Dystonia Rating Scale for rating generalized dystonia. Two “recommended” scales (VHI and VPQ) are generic scales validated on few patients with laryngeal dystonia, whereas the others are disease-specific scales. Twelve scales met criteria for “suggested” and seven scales met criteria for “listed”. All the scales are individually reviewed in the online appendix. Conclusion The task force recommends five specific dystonia scales and suggests to further validate in dystonia two recommended generic voice-disorder scales. Existing scales for oromandibular, arm and task-specific dystonia should be refined and fully assessed. Scales should be developed for body regions where no scales are available, such as lower limbs and trunk. PMID:23893443

Assessing communication quality of consultations in primary care: initial reliability of the Global Consultation Rating Scale, based on the Calgary-Cambridge Guide to the Medical Interview

PubMed Central

Burt, Jenni; Abel, Gary; Elmore, Natasha; Campbell, John; Roland, Martin; Benson, John; Silverman, Jonathan

2014-01-01

Objectives To investigate initial reliability of the Global Consultation Rating Scale (GCRS: an instrument to assess the effectiveness of communication across an entire doctor–patient consultation, based on the Calgary-Cambridge guide to the medical interview), in simulated patient consultations. Design Multiple ratings of simulated general practitioner (GP)–patient consultations by trained GP evaluators. Setting UK primary care. Participants 21 GPs and six trained GP evaluators. Outcome measures GCRS score. Methods 6 GP raters used GCRS to rate randomly assigned video recordings of GP consultations with simulated patients. Each of the 42 consultations was rated separately by four raters. We considered whether a fixed difference between scores had the same meaning at all levels of performance. We then examined the reliability of GCRS using mixed linear regression models. We augmented our regression model to also examine whether there were systematic biases between the scores given by different raters and to look for possible order effects. Results Assessing the communication quality of individual consultations, GCRS achieved a reliability of 0.73 (95% CI 0.44 to 0.79) for two raters, 0.80 (0.54 to 0.85) for three and 0.85 (0.61 to 0.88) for four. We found an average difference of 1.65 (on a 0–10 scale) in the scores given by the least and most generous raters: adjusting for this evaluator bias increased reliability to 0.78 (0.53 to 0.83) for two raters; 0.85 (0.63 to 0.88) for three and 0.88 (0.69 to 0.91) for four. There were considerable order effects, with later consultations (after 15–20 ratings) receiving, on average, scores more than one point higher on a 0–10 scale. Conclusions GCRS shows good reliability with three raters assessing each consultation. We are currently developing the scale further by assessing a large sample of real-world consultations. PMID:24604483

Uplink Downlink Rate Balancing and Throughput Scaling in FDD Massive MIMO Systems

NASA Astrophysics Data System (ADS)

Bergel, Itsik; Perets, Yona; Shamai, Shlomo

2016-05-01

In this work we extend the concept of uplink-downlink rate balancing to frequency division duplex (FDD) massive MIMO systems. We consider a base station with large number antennas serving many single antenna users. We first show that any unused capacity in the uplink can be traded off for higher throughput in the downlink in a system that uses either dirty paper (DP) coding or linear zero-forcing (ZF) precoding. We then also study the scaling of the system throughput with the number of antennas in cases of linear Beamforming (BF) Precoding, ZF Precoding, and DP coding. We show that the downlink throughput is proportional to the logarithm of the number of antennas. While, this logarithmic scaling is lower than the linear scaling of the rate in the uplink, it can still bring significant throughput gains. For example, we demonstrate through analysis and simulation that increasing the number of antennas from 4 to 128 will increase the throughput by more than a factor of 5. We also show that a logarithmic scaling of downlink throughput as a function of the number of receive antennas can be achieved even when the number of transmit antennas only increases logarithmically with the number of receive antennas.

Hyperviscosity for unstructured ALE meshes

NASA Astrophysics Data System (ADS)

Cook, Andrew W.; Ulitsky, Mark S.; Miller, Douglas S.

2013-01-01

An artificial viscosity, originally designed for Eulerian schemes, is adapted for use in arbitrary Lagrangian-Eulerian simulations. Changes to the Eulerian model (dubbed 'hyperviscosity') are discussed, which enable it to work within a Lagrangian framework. New features include a velocity-weighted grid scale and a generalised filtering procedure, applicable to either structured or unstructured grids. The model employs an artificial shear viscosity for treating small-scale vorticity and an artificial bulk viscosity for shock capturing. The model is based on the Navier-Stokes form of the viscous stress tensor, including the diagonal rate-of-expansion tensor. A second-order version of the model is presented, in which Laplacian operators act on the velocity divergence and the grid-weighted strain-rate magnitude to ensure that the velocity field remains smooth at the grid scale. Unlike sound-speed-based artificial viscosities, the hyperviscosity model is compatible with the low Mach number limit. The new model outperforms a commonly used Lagrangian artificial viscosity on a variety of test problems.

Plasmoid Instability in Forming Current Sheets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Comisso, L.; Lingam, M.; Huang, Y. -M.

The plasmoid instability has revolutionized our understanding of magnetic reconnection in astrophysical environments. By preventing the formation of highly elongated reconnection layers, it is crucial in enabling the rapid energy conversion rates that are characteristic of many astrophysical phenomena. Most previous studies have focused on Sweet–Parker current sheets, which are unattainable in typical astrophysical systems. Here we derive a general set of scaling laws for the plasmoid instability in resistive and visco-resistive current sheets that evolve over time. Our method relies on a principle of least time that enables us to determine the properties of the reconnecting current sheet (aspect ratio and elapsed time) and the plasmoid instability (growth rate, wavenumber, inner layer width) at the end of the linear phase. After this phase the reconnecting current sheet is disrupted and fast reconnection can occur. The scaling laws of the plasmoid instability are not simple power laws, and they depend on the Lundquist number (S), the magnetic Prandtl number (P m), the noise of the system (more » $${\\psi }_{0}$$), the characteristic rate of current sheet evolution ($$1/\\tau $$), and the thinning process. We also demonstrate that previous scalings are inapplicable to the vast majority of astrophysical systems. Furthermore, we explore the implications of the new scaling relations in astrophysical systems such as the solar corona and the interstellar medium. In both of these systems, we show that our scaling laws yield values for the growth rate, wavenumber, and aspect ratio that are much smaller than the Sweet–Parker–based scalings.« less

Plasmoid Instability in Forming Current Sheets

DOE PAGES

Comisso, L.; Lingam, M.; Huang, Y. -M.; ...

2017-11-28

The plasmoid instability has revolutionized our understanding of magnetic reconnection in astrophysical environments. By preventing the formation of highly elongated reconnection layers, it is crucial in enabling the rapid energy conversion rates that are characteristic of many astrophysical phenomena. Most previous studies have focused on Sweet–Parker current sheets, which are unattainable in typical astrophysical systems. Here we derive a general set of scaling laws for the plasmoid instability in resistive and visco-resistive current sheets that evolve over time. Our method relies on a principle of least time that enables us to determine the properties of the reconnecting current sheet (aspect ratio and elapsed time) and the plasmoid instability (growth rate, wavenumber, inner layer width) at the end of the linear phase. After this phase the reconnecting current sheet is disrupted and fast reconnection can occur. The scaling laws of the plasmoid instability are not simple power laws, and they depend on the Lundquist number (S), the magnetic Prandtl number (P m), the noise of the system (more » $${\\psi }_{0}$$), the characteristic rate of current sheet evolution ($$1/\\tau $$), and the thinning process. We also demonstrate that previous scalings are inapplicable to the vast majority of astrophysical systems. Furthermore, we explore the implications of the new scaling relations in astrophysical systems such as the solar corona and the interstellar medium. In both of these systems, we show that our scaling laws yield values for the growth rate, wavenumber, and aspect ratio that are much smaller than the Sweet–Parker–based scalings.« less

Completing the third person's perspective on patients' involvement in medical decision-making: approaching the full picture.

PubMed

Kasper, Jürgen; Hoffmann, Frauke; Heesen, Christoph; Köpke, Sascha; Geiger, Friedemann

2012-01-01

Shared decision making is based on the idea of cooperation and partnership between patients and doctors. In this concept both parties may initiate and perform specific decision-making steps. However, the common observation-based instruments focus solely on doctors' behaviour. Content and quality of information provided to involve patients in medical decisions are hardly considered in evaluation of SDM. This study investigates the advantages of a revised observer inventory taking into account these aspects. Based on the OPTION scale, a more comprehensive observation-based inventory was developed, additionally considering both the patient-sided indicators for patient involvement and the criteria of evidence-based patient information. The inventory comprises three scales (doctor, patient, doctor-patient dyad) and 15 indicators each. Rater training and re-analyses of 76 consultations previously analysed using the OPTION scale were conducted. Convergent validities were calculated between the observer-based scales and the patients' ratings on the Shared Decision Making Questionnaire, the Decisional Conflict Scale and the Control Preference Scale. Interrater reliabilities of the revised scales were high (r=.87 to .74) and even higher when only the dyadic perspective was coded (.86). The revised inventory provided additional information on the involvement taking place. No substantive correlations were found between observation-based and patients' subjective judgments. The observers' perspective on patient involvement needs to consider patient activities. Inconsistencies of patients' and observers' judgements concerning patient participation need further investigation. Copyright © 2012. Published by Elsevier GmbH.

Development and Validation of Triarchic Construct Scales from the Psychopathic Personality Inventory

PubMed Central

Hall, Jason R.; Drislane, Laura E.; Patrick, Christopher J.; Morano, Mario; Lilienfeld, Scott O.; Poythress, Norman G.

2014-01-01

The Triarchic model of psychopathy describes this complex condition in terms of distinct phenotypic components of boldness, meanness, and disinhibition. Brief self-report scales designed specifically to index these psychopathy facets have thus far demonstrated promising construct validity. The present study sought to develop and validate scales for assessing facets of the Triarchic model using items from a well-validated existing measure of psychopathy—the Psychopathic Personality Inventory (PPI). A consensus rating approach was used to identify PPI items relevant to each Triarchic facet, and the convergent and discriminant validity of the resulting PPI-based Triarchic scales were evaluated in relation to multiple criterion variables (i.e., other psychopathy inventories, antisocial personality disorder features, personality traits, psychosocial functioning) in offender and non-offender samples. The PPI-based Triarchic scales showed good internal consistency and related to criterion variables in ways consistent with predictions based on the Triarchic model. Findings are discussed in terms of implications for conceptualization and assessment of psychopathy. PMID:24447280

Development and validation of Triarchic construct scales from the psychopathic personality inventory.

PubMed

Hall, Jason R; Drislane, Laura E; Patrick, Christopher J; Morano, Mario; Lilienfeld, Scott O; Poythress, Norman G

2014-06-01

The Triarchic model of psychopathy describes this complex condition in terms of distinct phenotypic components of boldness, meanness, and disinhibition. Brief self-report scales designed specifically to index these psychopathy facets have thus far demonstrated promising construct validity. The present study sought to develop and validate scales for assessing facets of the Triarchic model using items from a well-validated existing measure of psychopathy-the Psychopathic Personality Inventory (PPI). A consensus-rating approach was used to identify PPI items relevant to each Triarchic facet, and the convergent and discriminant validity of the resulting PPI-based Triarchic scales were evaluated in relation to multiple criterion variables (i.e., other psychopathy inventories, antisocial personality disorder features, personality traits, psychosocial functioning) in offender and nonoffender samples. The PPI-based Triarchic scales showed good internal consistency and related to criterion variables in ways consistent with predictions based on the Triarchic model. Findings are discussed in terms of implications for conceptualization and assessment of psychopathy.

Effect of a Home-Based Lifestyle Intervention on Breastfeeding Initiation Among Socioeconomically Disadvantaged African American Women with Overweight or Obesity.

PubMed

Lewkowitz, Adam K; López, Julia D; Stein, Richard I; Rhoades, Janine S; Schulz, Rosa C; Woolfolk, Candice L; Macones, George A; Haire-Joshu, Debra; Cahill, Alison G

2018-06-18

Socioeconomically disadvantaged (SED) African American women with overweight or obesity are less likely to breastfeed. To test whether a home-based lifestyle intervention impacts breastfeeding initiation rates in SED African American women with overweight or obesity. This was a secondary analysis of a randomized controlled trial from October 2012 to March 2016 at a university-based hospital within the LIFE-Moms consortium. SED African American women with overweight or obesity and singleton gestations were randomized by 16 weeks to Parents as Teachers (PAT)-a home-based parenting support and child development educational intervention-or PAT+, PAT with additional content on breastfeeding. Participants completed a breastfeeding survey. Outcomes included breastfeeding initiation and reasons for not initiating or not continuing breastfeeding. One hundred eighteen women were included: 59 in PAT+; 59 in PAT. Breastfeeding initiation rates were similar in each group (78.00% in PAT+; 74.58% in PAT). On a one to four scale, with four denoting "very important," women in PAT+ and PAT were equally likely to rate their beliefs that formula was better than breast milk or breastfeeding would be too inconvenient as the most important reasons to not initiate breastfeeding. On the same scale, women similarly rated their difficulty latching or concern for low milk supply as the most important reasons for breastfeeding cessation. SED African American women with overweight or obesity who received a home-based educational intervention had higher breastfeeding rates than is reported nationally for black women (59%). However, the intervention with more breastfeeding content did not further increase breastfeeding rates or impact reasons for breastfeeding cessation. ClinicalTrials.gov : NCT01768793.

Scale-Dependent Rates of Uranyl Surface Complexation Reaction in Sediments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Chongxuan; Shang, Jianying; Kerisit, Sebastien N.

Scale-dependency of uranyl[U(VI)] surface complexation rates was investigated in stirred flow-cell and column systems using a U(VI)-contaminated sediment from the US Department of Energy, Hanford site, WA. The experimental results were used to estimate the apparent rate of U(VI) surface complexation at the grain-scale and in porous media. Numerical simulations using molecular, pore-scale, and continuum models were performed to provide insights into and to estimate the rate constants of U(VI) surface complexation at the different scales. The results showed that the grain-scale rate constant of U(VI) surface complexation was over 3 to 10 orders of magnitude smaller, dependent on themore » temporal scale, than the rate constant calculated using the molecular simulations. The grain-scale rate was faster initially and slower with time, showing the temporal scale-dependency. The largest rate constant at the grain-scale decreased additional 2 orders of magnitude when the rate was scaled to the porous media in the column. The scaling effect from the grain-scale to the porous media became less important for the slower sorption sites. Pore-scale simulations revealed the importance of coupled mass transport and reactions in both intragranular and inter-granular domains, which caused both spatial and temporal dependence of U(VI) surface complexation rates in the sediment. Pore-scale simulations also revealed a new rate-limiting mechanism in the intragranular porous domains that the rate of coupled diffusion and surface complexation reaction was slower than either process alone. The results provided important implications for developing models to scale geochemical/biogeochemical reactions.« less

Detecting cancer clusters in a regional population with local cluster tests and Bayesian smoothing methods: a simulation study

PubMed Central

2013-01-01

Background There is a rising public and political demand for prospective cancer cluster monitoring. But there is little empirical evidence on the performance of established cluster detection tests under conditions of small and heterogeneous sample sizes and varying spatial scales, such as are the case for most existing population-based cancer registries. Therefore this simulation study aims to evaluate different cluster detection methods, implemented in the open soure environment R, in their ability to identify clusters of lung cancer using real-life data from an epidemiological cancer registry in Germany. Methods Risk surfaces were constructed with two different spatial cluster types, representing a relative risk of RR = 2.0 or of RR = 4.0, in relation to the overall background incidence of lung cancer, separately for men and women. Lung cancer cases were sampled from this risk surface as geocodes using an inhomogeneous Poisson process. The realisations of the cancer cases were analysed within small spatial (census tracts, N = 1983) and within aggregated large spatial scales (communities, N = 78). Subsequently, they were submitted to the cluster detection methods. The test accuracy for cluster location was determined in terms of detection rates (DR), false-positive (FP) rates and positive predictive values. The Bayesian smoothing models were evaluated using ROC curves. Results With moderate risk increase (RR = 2.0), local cluster tests showed better DR (for both spatial aggregation scales > 0.90) and lower FP rates (both < 0.05) than the Bayesian smoothing methods. When the cluster RR was raised four-fold, the local cluster tests showed better DR with lower FPs only for the small spatial scale. At a large spatial scale, the Bayesian smoothing methods, especially those implementing a spatial neighbourhood, showed a substantially lower FP rate than the cluster tests. However, the risk increases at this scale were mostly diluted by data aggregation. Conclusion High resolution spatial scales seem more appropriate as data base for cancer cluster testing and monitoring than the commonly used aggregated scales. We suggest the development of a two-stage approach that combines methods with high detection rates as a first-line screening with methods of higher predictive ability at the second stage. PMID:24314148

The Behavior Problems Inventory-Short Form for individuals with intellectual disabilities: part I: development and provisional clinical reference data.

PubMed

Rojahn, J; Rowe, E W; Sharber, A C; Hastings, R; Matson, J L; Didden, R; Kroes, D B H; Dumont, E L M

2012-05-01

The Behavior Problems Inventory-01 (BPI-01) is an informant-based behaviour rating instrument that was designed to assess maladaptive behaviours in individuals with intellectual disabilities (ID). Its items fall into one of three sub-scales: Self-injurious Behavior (14 items), Stereotyped Behavior (24 items), and Aggressive/Destructive Behavior (11 items). Each item is rated on a frequency scale (0 = never to 4 = hourly), and a severity scale (0 = no problem to 3 = severe problem). The BPI-01 has been successfully used in several studies and has shown acceptable to very good psychometric properties. One concern raised by some investigators was the large number of items on the BPI-01, which has reduced its user friendliness for certain applications. Furthermore, researchers and clinicians were often uncertain how to interpret their BPI-01 data without norms or a frame of reference. The Behavior Problems Inventory-Short Form (BPI-S) was empirically developed, based on an aggregated archival data set of BPI-01 data from individuals with ID from nine locations in the USA, Wales, England, the Netherlands, and Romania (n = 1122). The BPI-S uses the same rating system and the same three sub-scales as the BPI-01, but has fewer items: Self-injurious Behavior (8 items), Stereotyped Behavior (12 items), and Aggressive/Destructive Behavior (10 items). Rating anchors for the severity scales of the Self-injurious Behavior and the Aggressive/Destructive Behavior sub-scales were added in an effort to enhance the objectivity of the ratings. The sensitivity of the BPI-S compared with the BPI-01 was high (0.92 to 0.99), and so were the correlations between the analogous BPI-01 and the BPI-S sub-scales (0.96 to 0.99). Means and standard deviations were generated for both BPI versions in a Sex-by-age matrix, and in a Sex-by-ID Level matrix. Combined sex ranges are also provided by age and level of ID. In summary, the BPI-S is a very useful alternative to the BPI-01, especially for research and evaluation purposes involving groups of individuals. © 2011 The Authors. Journal of Intellectual Disability Research © 2011 Blackwell Publishing Ltd.

A fuzzy-logic-based model to predict biogas and methane production rates in a pilot-scale mesophilic UASB reactor treating molasses wastewater.

PubMed

Turkdogan-Aydinol, F Ilter; Yetilmezsoy, Kaan

2010-10-15

A MIMO (multiple inputs and multiple outputs) fuzzy-logic-based model was developed to predict biogas and methane production rates in a pilot-scale 90-L mesophilic up-flow anaerobic sludge blanket (UASB) reactor treating molasses wastewater. Five input variables such as volumetric organic loading rate (OLR), volumetric total chemical oxygen demand (TCOD) removal rate (R(V)), influent alkalinity, influent pH and effluent pH were fuzzified by the use of an artificial intelligence-based approach. Trapezoidal membership functions with eight levels were conducted for the fuzzy subsets, and a Mamdani-type fuzzy inference system was used to implement a total of 134 rules in the IF-THEN format. The product (prod) and the centre of gravity (COG, centroid) methods were employed as the inference operator and defuzzification methods, respectively. Fuzzy-logic predicted results were compared with the outputs of two exponential non-linear regression models derived in this study. The UASB reactor showed a remarkable performance on the treatment of molasses wastewater, with an average TCOD removal efficiency of 93 (+/-3)% and an average volumetric TCOD removal rate of 6.87 (+/-3.93) kg TCOD(removed)/m(3)-day, respectively. Findings of this study clearly indicated that, compared to non-linear regression models, the proposed MIMO fuzzy-logic-based model produced smaller deviations and exhibited a superior predictive performance on forecasting of both biogas and methane production rates with satisfactory determination coefficients over 0.98. 2010 Elsevier B.V. All rights reserved.

Continent-Wide Estimates of Antarctic Strain Rates from Landsat 8-Derived Velocity Grids and Their Application to Ice Shelf Studies

NASA Astrophysics Data System (ADS)

Alley, K. E.; Scambos, T.; Anderson, R. S.; Rajaram, H.; Pope, A.; Haran, T.

2017-12-01

Strain rates are fundamental measures of ice flow used in a wide variety of glaciological applications including investigations of bed properties, calculations of basal mass balance on ice shelves, application to Glen's flow law, and many other studies. However, despite their extensive application, strain rates are calculated using widely varying methods and length scales, and the calculation details are often not specified. In this study, we compare the results of nominal and logarithmic strain-rate calculations based on a satellite-derived velocity field of the Antarctic ice sheet generated from Landsat 8 satellite data. Our comparison highlights the differences between the two commonly used approaches in the glaciological literature. We evaluate the errors introduced by each code and their impacts on the results. We also demonstrate the importance of choosing and specifying a length scale over which strain-rate calculations are made, which can have large local impacts on other derived quantities such as basal mass balance on ice shelves. We present strain-rate data products calculated using an approximate viscous length-scale with satellite observations of ice velocity for the Antarctic continent. Finally, we explore the applications of comprehensive strain-rate maps to future ice shelf studies, including investigations of ice fracture, calving patterns, and stability analyses.

Climate fails to predict wood decomposition at regional scales

NASA Astrophysics Data System (ADS)

Bradford, Mark A.; Warren, Robert J., II; Baldrian, Petr; Crowther, Thomas W.; Maynard, Daniel S.; Oldfield, Emily E.; Wieder, William R.; Wood, Stephen A.; King, Joshua R.

2014-07-01

Decomposition of organic matter strongly influences ecosystem carbon storage. In Earth-system models, climate is a predominant control on the decomposition rates of organic matter. This assumption is based on the mean response of decomposition to climate, yet there is a growing appreciation in other areas of global change science that projections based on mean responses can be irrelevant and misleading. We test whether climate controls on the decomposition rate of dead wood--a carbon stock estimated to represent 73 +/- 6 Pg carbon globally--are sensitive to the spatial scale from which they are inferred. We show that the common assumption that climate is a predominant control on decomposition is supported only when local-scale variation is aggregated into mean values. Disaggregated data instead reveal that local-scale factors explain 73% of the variation in wood decomposition, and climate only 28%. Further, the temperature sensitivity of decomposition estimated from local versus mean analyses is 1.3-times greater. Fundamental issues with mean correlations were highlighted decades ago, yet mean climate-decomposition relationships are used to generate simulations that inform management and adaptation under environmental change. Our results suggest that to predict accurately how decomposition will respond to climate change, models must account for local-scale factors that control regional dynamics.

Extensions and evaluations of a general quantitative theory of forest structure and dynamics

PubMed Central

Enquist, Brian J.; West, Geoffrey B.; Brown, James H.

2009-01-01

Here, we present the second part of a quantitative theory for the structure and dynamics of forests under demographic and resource steady state. The theory is based on individual-level allometric scaling relations for how trees use resources, fill space, and grow. These scale up to determine emergent properties of diverse forests, including size–frequency distributions, spacing relations, canopy configurations, mortality rates, population dynamics, successional dynamics, and resource flux rates. The theory uniquely makes quantitative predictions for both stand-level scaling exponents and normalizations. We evaluate these predictions by compiling and analyzing macroecological datasets from several tropical forests. The close match between theoretical predictions and data suggests that forests are organized by a set of very general scaling rules. Our mechanistic theory is based on allometric scaling relations, is complementary to “demographic theory,” but is fundamentally different in approach. It provides a quantitative baseline for understanding deviations from predictions due to other factors, including disturbance, variation in branching architecture, asymmetric competition, resource limitation, and other sources of mortality, which are not included in the deliberately simplified theory. The theory should apply to a wide range of forests despite large differences in abiotic environment, species diversity, and taxonomic and functional composition. PMID:19363161

Teaching aseptic technique for central venous access under ultrasound guidance: a randomized trial comparing didactic training alone to didactic plus simulation-based training.

PubMed

Latif, Rana K; Bautista, Alexander F; Memon, Saima B; Smith, Elizabeth A; Wang, Chenxi; Wadhwa, Anupama; Carter, Mary B; Akca, Ozan

2012-03-01

Our goal was to determine whether simulation combined with didactic training improves sterile technique during ultrasound (US)-guided central venous catheter (CVC) insertion compared with didactic training alone among novices. We hypothesized that novices who receive combined didactic and simulation-based training would perform similarly to experienced residents in aseptic technique, knowledge, and perception of comfort during US-guided CVC insertion on a simulator. Seventy-two subjects were enrolled in a randomized, controlled trial of an educational intervention. Fifty-four novices were randomized into either the didactic group or the simulation combined with didactic group. Both groups received didactic training but the simulation combined with didactic group also received simulation-based CVC insertion training. Both groups were tested by demonstrating US-guided CVC insertion on a simulator. Aseptic technique was scored on 8 steps as "yes/no" and also using a 7-point Likert scale with 7 being "excellent technique" by a rater blinded to subject randomization. After initial testing, the didactic group was offered simulation-based training and retesting. Both groups also took a pre- and posttraining test of knowledge and rated their comfort with US and CVC insertion pre- and posttraining on a 5-point Likert scale. Subsequently, 18 experienced residents also took the test of knowledge, rated their comfort level, and were scored while performing aseptic US-guided CVC insertion using a simulator. The simulation combined with didactic group achieved a 167% (95% confidence interval [CI] 133%-167%) incremental increase in yes/no scores and 115% (CI 112%-127%) incremental increase in Likert scale ratings on aseptic technique compared with novices in the didactic group. Compared with experienced residents, simulation combined with didactic trained novices achieved an increase in aseptic scores with a 33.3% (CI 16.7%-50%) increase in yes/no ratings and a 20% (CI 13.3%-40%) increase in Likert scaled ratings, and scored 2.5-fold higher on the test of knowledge. There was a 3-fold increase in knowledge and 2-fold increase in comfort level among all novices (P < 0.001) after combined didactic and simulation-based training. Simulation combined with didactic training is superior to didactic training alone for acquisition of clinical skills such as US-guided CVC insertion. After combined didactic and simulation-based training, novices can outperform experienced residents in aseptic technique as well as in measurements of knowledge.

Comparing Time-Dependent Geomagnetic and Atmospheric Effects on Cosmogenic Nuclide Production Rate Scaling

NASA Astrophysics Data System (ADS)

Lifton, N. A.

2014-12-01

A recently published cosmogenic nuclide production rate scaling model based on analytical fits to Monte Carlo simulations of atmospheric cosmic ray flux spectra (both of which agree well with measured spectra) (Lifton et al., 2014, Earth Planet. Sci. Lett. 386, 149-160: termed the LSD model) provides two main advantages over previous scaling models: identification and quantification of potential sources of bias in the earlier models, and the ability to generate nuclide-specific scaling factors easily for a wide range of input parameters. The new model also provides a flexible framework for exploring the implications of advances in model inputs. In this work, the scaling implications of two recent time-dependent spherical harmonic geomagnetic models spanning the Holocene will be explored. Korte and Constable (2011, Phys. Earth Planet. Int. 188, 247-259) and Korte et al. (2011, Earth Planet. Sci. Lett. 312, 497-505) recently updated earlier spherical harmonic paleomagnetic models used by Lifton et al. (2014) with paleomagnetic measurements from sediment cores in addition to archeomagnetic and volcanic data. These updated models offer improved accuracy over the previous versions, in part to due to increased temporal and spatial data coverage. With the new models as input, trajectory-traced estimates of effective vertical cutoff rigidity (RC- the standard method for ordering cosmic ray data) yield significantly different time-integrated scaling predictions when compared to the earlier models. These results will be compared to scaling predictions using another recent time-dependent spherical harmonic model of the Holocene geomagnetic field by Pavón-Carrasco et al. (2014, Earth Planet. Sci. Lett. 388, 98-109), based solely on archeomagnetic and volcanic paleomagnetic data, but extending to 14 ka. In addition, the potential effects of time-dependent atmospheric models on LSD scaling predictions will be presented. Given the typical dominance of altitudinal over latitudinal scaling effects on cosmogenic nuclide production, incorporating transient global simulations of atmospheric structure (e.g., Liu et al., 2009, Science 325, 310-314) into scaling frameworks may contribute to improved understanding of long-term production rate variations.

Pore-scale simulation of calcium carbonate precipitation and dissolution under highly supersaturated conditions in a microfludic pore network

NASA Astrophysics Data System (ADS)

Yoon, H.; Dewers, T. A.; Valocchi, A. J.; Werth, C. J.

2011-12-01

Dissolved CO2 during geological CO2 storage may react with minerals in fractured rocks or confined aquifers and cause mineral precipitation. The overall rate of reaction can be affected by coupled processes among hydrodynamics, transport, and reactions at pore-scale. Pore-scale models of coupled fluid flow, reactive transport, and CaCO3 precipitation and dissolution are applied to account for transient experimental results of CaCO3 precipitation and dissolution under highly supersaturated conditions in a microfluidic pore network (i.e., micromodel). Pore-scale experiments in the micromodel are used as a basis for understanding coupled physics of systems perturbed by geological CO2 injection. In the micromodel, precipitation is induced by transverse mixing along the centerline in pore bodies. Overall, the pore-scale model qualitatively captured the governing physics of reactions such as precipitate morphology, precipitation rate, and maximum precipitation area in first few pore spaces. In particular, we found that proper estimation of the effective diffusion coefficient and the reactive surface area is necessary to adequately simulate precipitation and dissolution rates. As the model domain increases, the effect of flow patterns affected by precipitation on the overall reaction rate also increases. The model is also applied to account for the effect of different reaction rate laws on mineral precipitation and dissolution at pore-scale. Reaction rate laws tested include the linear rate law, nonlinear power law, and newly-developed rate law based on in-situ measurements at nano scale in the literature. Progress on novel methods for upscaling pore-scale models for reactive transport are discussed, and are being applied to mineral precipitation patterns observed in natural analogues. H.Y. and T. D. were supported as part of the Center for Frontiers of Subsurface Energy Security, an Energy Frontier Research Center funded by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences under Award Number DE-SC0001114. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

Process-based principles for restoring river ecosystems

Treesearch

Timothy J. Beechie; David A. Sear; Julian D. Olden; George R. Pess; John M. Buffington; Hamish Moir; Philip Roni; Michael M. Pollock

2010-01-01

Process-based restoration aims to reestablish normative rates and magnitudes of physical, chemical, and biological processes that sustain river and floodplain ecosystems. Ecosystem conditions at any site are governed by hierarchical regional, watershed, and reach-scale processes controlling hydrologic and sediment regimes; floodplain and aquatic habitat...

Axisymmetric computational fluid dynamics analysis of a film/dump-cooled rocket nozzle plume

NASA Technical Reports Server (NTRS)

Tucker, P. K.; Warsi, S. A.

1993-01-01

Prediction of convective base heating rates for a new launch vehicle presents significant challenges to analysts concerned with base environments. The present effort seeks to augment classical base heating scaling techniques via a detailed investigation of the exhaust plume shear layer of a single H2/O2 Space Transportation Main Engine (STME). Use of fuel-rich turbine exhaust to cool the STME nozzle presented concerns regarding potential recirculation of these gases to the base region with attendant increase in the base heating rate. A pressure-based full Navier-Stokes computational fluid dynamics (CFD) code with finite rate chemistry is used to predict plumes for vehicle altitudes of 10 kft and 50 kft. Levels of combustible species within the plume shear layers are calculated in order to assess assumptions made in the base heating analysis.

Faces scales for the measurement of postoperative pain intensity in children following minor surgery.

PubMed

Chambers, Christine T; Hardial, Janine; Craig, Kenneth D; Court, Colleen; Montgomery, Carolyne

2005-01-01

Faces scales are commonly used to obtain self-reports of pain intensity from children. Previous research using hypothetical vignettes and pain following venepuncture has found differences in children's pain ratings as a function of the type of faces scale used. The purpose of the present study was to determine whether scales beginning with a smiling rather than neutral "no pain" face would produce higher ratings in the assessment of postoperative pain intensity in children and to compare ratings using different faces scales to those reported with an additional independent measure of pain intensity. Participants were 78 children between the ages of 5 and 13 years undergoing surgery, one of their parents, and their postoperative care nurse. Following surgery, children were asked to provide a rating of their current pain intensity using a set of 5 successively administered faces scales and the Colored Analog Scale (CAS). Parents and nurses provided independent ratings using the same measures. Results showed that parents and nurses rated significantly more pain when using scales with a smiling rather than a neutral "no pain" face. This pattern was not as clear for the children's ratings, although their highest ratings were provided when using a smiling "no pain" faces scale. Children's and nurses' ratings on the CAS were generally more similar to their ratings using scales with neutral "no pain" faces, whereas parents' CAS ratings tended to fall in between ratings provided on the smiling and neutral "no pain" faces scales. Scale preference, age and sex differences in pain ratings, and child-parent-nurse agreement in pain ratings are also examined. Children's and parents' ratings of postoperative pain intensity are influenced by the presence of a smiling "no pain" face at the beginning of faces scales, with such scales producing significantly higher ratings than scales with neutral "no pain" faces. Ratings on the independent CAS measure were more comparable to those provided on faces scales with neutral "no pain" faces. Nurses are also susceptible to the influencing effect of a smiling face at the beginning of a faces scale.

A trust-based recommendation method using network diffusion processes

NASA Astrophysics Data System (ADS)

Chen, Ling-Jiao; Gao, Jian

2018-09-01

A variety of rating-based recommendation methods have been extensively studied including the well-known collaborative filtering approaches and some network diffusion-based methods, however, social trust relations are not sufficiently considered when making recommendations. In this paper, we contribute to the literature by proposing a trust-based recommendation method, named CosRA+T, after integrating the information of trust relations into the resource-redistribution process. Specifically, a tunable parameter is used to scale the resources received by trusted users before the redistribution back to the objects. Interestingly, we find an optimal scaling parameter for the proposed CosRA+T method to achieve its best recommendation accuracy, and the optimal value seems to be universal under several evaluation metrics across different datasets. Moreover, results of extensive experiments on the two real-world rating datasets with trust relations, Epinions and FriendFeed, suggest that CosRA+T has a remarkable improvement in overall accuracy, diversity and novelty. Our work takes a step towards designing better recommendation algorithms by employing multiple resources of social network information.

The Application of Structured Job Analysis Information Based on the Position Analysis Questionnaire (PAQ).

DTIC Science & Technology

Position Analysis Questionnaire ( PAQ ). This job analysis instrument consists of 187 job elements organized into six divisions. In the analysis of a job...with the PAQ the relevance of the individual elements to the job are rated using any of several rating scales such as importance, or time.

Evaluating the Effectiveness of Rating Instruments for a Communication Skills Assessment of Medical Residents

ERIC Educational Resources Information Center

Iramaneerat, Cherdsak; Myford, Carol M.; Yudkowsky, Rachel; Lowenstein, Tali

2009-01-01

The investigators used evidence based on response processes to evaluate and improve the validity of scores on the Patient-Centered Communication and Interpersonal Skills (CIS) Scale for the assessment of residents' communication competence. The investigators retrospectively analyzed the communication skills ratings of 68 residents at the…

Validation of Scratching Severity as an Objective Assessment for Itch.

PubMed

Udkoff, Jeremy; Silverberg, Jonathan I

2018-05-01

There are currently no simple, standardized, objective assessments of itch for clinical trials and practice. We sought to validate and test the severity of scratching as an objective measure of itch (4-point ordinal scale ranging from 0 [not present] to 3 [very prominent] based on the observation of scratching lesions). We performed a prospective outpatient study using questionnaires and evaluations by a dermatologist in adults with atopic dermatitis (n = 261). Severity of scratching best correlated with patient-reported global atopic dermatitis severity (Kendall τ = 0.336, P < 0.0001), numeric rating scale of itch in the past 24 hours (τ = 0.266, P = 0.0010) and 3 days (τ = 0.296, P < 0.0001). Severity of scratching showed responsiveness over time. Patients experiencing improvement of scratching severity of 1 point or greater had significantly lower itch based on numeric rating scale in the past 3 days (Wilcoxon rank sum test, P = 0.0175), 5-D itch scale (P = 0.0146), and Patient-Oriented Eczema Measure scores (P = 0.0146). There was a significant decrease in scratching severity for patients experiencing itch improvement of 4 points or greater in the past 3 days on the numeric rating scale (Fisher exact test, P = 0.0026), Patient-Oriented Eczema Measure (P < 0.0001), and Dermatology Life Quality Index (P = 0.0285). Severity of scratching may be a useful endpoint in clinical trials and practice across the gamut of pruritic disorders. Future studies are needed to validate severity of scratching in other pruritic disease. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

A Langevin equation for the rates of currency exchange based on the Markov analysis

NASA Astrophysics Data System (ADS)

Farahpour, F.; Eskandari, Z.; Bahraminasab, A.; Jafari, G. R.; Ghasemi, F.; Sahimi, Muhammad; Reza Rahimi Tabar, M.

2007-11-01

We propose a method for analyzing the data for the rates of exchange of various currencies versus the U.S. dollar. The method analyzes the return time series of the data as a Markov process, and develops an effective equation which reconstructs it. We find that the Markov time scale, i.e., the time scale over which the data are Markov-correlated, is one day for the majority of the daily exchange rates that we analyze. We derive an effective Langevin equation to describe the fluctuations in the rates. The equation contains two quantities, D and D, representing the drift and diffusion coefficients, respectively. We demonstrate how the two coefficients are estimated directly from the data, without using any assumptions or models for the underlying stochastic time series that represent the daily rates of exchange of various currencies versus the U.S. dollar.

A Protection Motivation Theory-Based Scale for Tobacco Research among Chinese Youth

PubMed Central

MacDonell, Karen; Chen, Xinguang; Yan, Yaqiong; Li, Fang; Gong, Jie; Sun, Huiling; Li, Xiaoming; Stanton, Bonita

2014-01-01

Rates of tobacco use among adolescents in China and other lower and middle-income countries remain high despite notable prevention and intervention programs. One reason for this may be the lack of theory-based research in tobacco use prevention in these countries. In the current study, a culturally appropriate 21-item measurement scale for cigarette smoking was developed based on the core constructs of Protection Motivation Theory (PMT). The scale was assessed among a sample of 553 Chinese vocational high school students. Results from correlational and measurement modeling analysis indicated adequate measurement reliability for the proposed PMT scale structure. The two PMT Pathways and the seven PMT constructs were significantly correlated with adolescent intention to smoke and actual smoking behavior. This study is the first to evaluate a PMT scale for cigarette smoking among Chinese adolescents. The scale provides a potential tool for assessing social cognitive processes underlying tobacco use. This is essential for understanding smoking behavior among Chinese youth and to support more effective tobacco use prevention efforts. Additional studies are needed to assess its utility for use with Chinese youth in other settings. PMID:24478933

Simulation-based Assessment of the Management of Critical Events by Board-certified Anesthesiologists.

PubMed

Weinger, Matthew B; Banerjee, Arna; Burden, Amanda R; McIvor, William R; Boulet, John; Cooper, Jeffrey B; Steadman, Randolph; Shotwell, Matthew S; Slagle, Jason M; DeMaria, Samuel; Torsher, Laurence; Sinz, Elizabeth; Levine, Adam I; Rask, John; Davis, Fred; Park, Christine; Gaba, David M

2017-09-01

We sought to determine whether mannequin-based simulation can reliably characterize how board-certified anesthesiologists manage simulated medical emergencies. Our primary focus was to identify gaps in performance and to establish psychometric properties of the assessment methods. A total of 263 consenting board-certified anesthesiologists participating in existing simulation-based maintenance of certification courses at one of eight simulation centers were video recorded performing simulated emergency scenarios. Each participated in two 20-min, standardized, high-fidelity simulated medical crisis scenarios, once each as primary anesthesiologist and first responder. Via a Delphi technique, an independent panel of expert anesthesiologists identified critical performance elements for each scenario. Trained, blinded anesthesiologists rated video recordings using standardized rating tools. Measures included the percentage of critical performance elements observed and holistic (one to nine ordinal scale) ratings of participant's technical and nontechnical performance. Raters also judged whether the performance was at a level expected of a board-certified anesthesiologist. Rater reliability for most measures was good. In 284 simulated emergencies, participants were rated as successfully completing 81% (interquartile range, 75 to 90%) of the critical performance elements. The median rating of both technical and nontechnical holistic performance was five, distributed across the nine-point scale. Approximately one-quarter of participants received low holistic ratings (i.e., three or less). Higher-rated performances were associated with younger age but not with previous simulation experience or other individual characteristics. Calling for help was associated with better individual and team performance. Standardized simulation-based assessment identified performance gaps informing opportunities for improvement. If a substantial proportion of experienced anesthesiologists struggle with managing medical emergencies, continuing medical education activities should be reevaluated.

Inter-rater reliability and aspects of validity of the parent-infant relationship global assessment scale (PIR-GAS)

PubMed Central

2013-01-01

Background The Parent-Infant Relationship Global Assessment Scale (PIR-GAS) signifies a conceptually relevant development in the multi-axial, developmentally sensitive classification system DC:0-3R for preschool children. However, information about the reliability and validity of the PIR-GAS is rare. A review of the available empirical studies suggests that in research, PIR-GAS ratings can be based on a ten-minute videotaped interaction sequence. The qualification of raters may be very heterogeneous across studies. Methods To test whether the use of the PIR-GAS still allows for a reliable assessment of the parent-infant relationship, our study compared a PIR-GAS ratings based on a full-information procedure across multiple settings with ratings based on a ten-minute video by two doctoral candidates of medicine. For each mother-child dyad at a family day hospital (N = 48), we obtained two video ratings and one full-information rating at admission to therapy and at discharge. This pre-post design allowed for a replication of our findings across the two measurement points. We focused on the inter-rater reliability between the video coders, as well as between the video and full-information procedure, including mean differences and correlations between the raters. Additionally, we examined aspects of the validity of video and full-information ratings based on their correlation with measures of child and maternal psychopathology. Results Our results showed that a ten-minute video and full-information PIR-GAS ratings were not interchangeable. Most results at admission could be replicated by the data obtained at discharge. We concluded that a higher degree of standardization of the assessment procedure should increase the reliability of the PIR-GAS, and a more thorough theoretical foundation of the manual should increase its validity. PMID:23705962

Realizing a terrestrial reference frame using the Global Positioning System

NASA Astrophysics Data System (ADS)

Haines, Bruce J.; Bar-Sever, Yoaz E.; Bertiger, Willy I.; Desai, Shailen D.; Harvey, Nate; Sibois, Aurore E.; Weiss, Jan P.

2015-08-01

We describe a terrestrial reference frame (TRF) realization based on Global Positioning System (GPS) data alone. Our approach rests on a highly dynamic, long-arc (9 day) estimation strategy and on GPS satellite antenna calibrations derived from Gravity Recovery and Climate Experiment and TOPEX/Poseidon low Earth orbit receiver GPS data. Based on nearly 17 years of data (1997-2013), our solution for scale rate agrees with International Terrestrial Reference Frame (ITRF)2008 to 0.03 ppb yr-1, and our solution for 3-D origin rate agrees with ITRF2008 to 0.4 mm yr-1. Absolute scale differs by 1.1 ppb (7 mm at the Earth's surface) and 3-D origin by 8 mm. These differences lie within estimated error levels for the contemporary TRF.

[Fool's gold standards in language screening. Sensitivity and specificity of the Hessian child language screening test (Kindersprachscreening, KiSS)].

PubMed

Neumann, K; Holler-Zittlau, I; van Minnen, S; Sick, U; Zaretsky, Y; Euler, H A

2011-01-01

The German Kindersprachscreening (KiSS) is a universal speech and language screening test for large-scale identification of Hessian kindergarten children requiring special educational language training or clinical speech/language therapy. To calculate the procedural screening validity, 257 children (aged 4.0 to 4.5 years) were tested using KiSS and four language tests (Reynell Development Language Scales III, Patholinguistische Diagnostik, PLAKSS, AWST-R). The majority or consensus judgements of three speech-language professionals, based on the language test results, served as a reference criterion. The base (fail) rates of the professionals were either self-determined or preset based on known prevalence rates. Screening validity was higher for preset than for self-determined base rates due to higher inter-judge agreement. The confusion matrices of the overall index classification of the KiSS (speech-language abnormalities with educational or clinical needs) with the fixed base rate expert judgement about language impairment, including fluency or voice disorders, yielded a sensitivity of 88% and a specificity of 78%, for just language impairment 84% and 75%, respectively. Specificities for disorders requiring clinical diagnostics in the KiSS (language impairment alone or combined with fluency/voice disorders) related to the test-based consensus expert judgment was about 93%. Sensitivities were unsatisfactory because the differentiation between educational and clinical needs requires improvement. Since the judgement concordances between the speech-language professionals was only moderate, the development of a comprehensive German reference test for speech and language disorders with evidence-based algorithmic decision rules rather than subjective clinical judgement is advocated.

Novel method to construct large-scale design space in lubrication process utilizing Bayesian estimation based on a small-scale design-of-experiment and small sets of large-scale manufacturing data.

PubMed

Maeda, Jin; Suzuki, Tatsuya; Takayama, Kozo

2012-12-01

A large-scale design space was constructed using a Bayesian estimation method with a small-scale design of experiments (DoE) and small sets of large-scale manufacturing data without enforcing a large-scale DoE. The small-scale DoE was conducted using various Froude numbers (X(1)) and blending times (X(2)) in the lubricant blending process for theophylline tablets. The response surfaces, design space, and their reliability of the compression rate of the powder mixture (Y(1)), tablet hardness (Y(2)), and dissolution rate (Y(3)) on a small scale were calculated using multivariate spline interpolation, a bootstrap resampling technique, and self-organizing map clustering. The constant Froude number was applied as a scale-up rule. Three experiments under an optimal condition and two experiments under other conditions were performed on a large scale. The response surfaces on the small scale were corrected to those on a large scale by Bayesian estimation using the large-scale results. Large-scale experiments under three additional sets of conditions showed that the corrected design space was more reliable than that on the small scale, even if there was some discrepancy in the pharmaceutical quality between the manufacturing scales. This approach is useful for setting up a design space in pharmaceutical development when a DoE cannot be performed at a commercial large manufacturing scale.

FAST TRACK COMMUNICATION High rate straining of tantalum and copper

NASA Astrophysics Data System (ADS)

Armstrong, R. W.; Zerilli, F. J.

2010-12-01

High strain rate measurements reported recently for several tantalum and copper crystal/polycrystal materials are shown to follow dislocation mechanics-based constitutive relations, first at lower strain rates, for dislocation velocity control of the imposed plastic deformations and, then at higher rates, transitioning to nano-scale dislocation generation control by twinning or slip. For copper, there is the possibility of added-on slip dislocation displacements to be accounted for from the newly generated dislocations.

An individual-based model of skipjack tuna (Katsuwonus pelamis) movement in the tropical Pacific ocean

NASA Astrophysics Data System (ADS)

Scutt Phillips, Joe; Sen Gupta, Alex; Senina, Inna; van Sebille, Erik; Lange, Michael; Lehodey, Patrick; Hampton, John; Nicol, Simon

2018-05-01

The distribution of marine species is often modeled using Eulerian approaches, in which changes to population density or abundance are calculated at fixed locations in space. Conversely, Lagrangian, or individual-based, models simulate the movement of individual particles moving in continuous space, with broader-scale patterns such as distribution being an emergent property of many, potentially adaptive, individuals. These models offer advantages in examining dynamics across spatiotemporal scales and making comparisons with observations from individual-scale data. Here, we introduce and describe such a model, the Individual-based Kinesis, Advection and Movement of Ocean ANimAls model (Ikamoana), which we use to replicate the movement processes of an existing Eulerian model for marine predators (the Spatial Ecosystem and Population Dynamics Model, SEAPODYM). Ikamoana simulates the movement of either individual or groups of animals by physical ocean currents, habitat-dependent stochastic movements (kinesis), and taxis movements representing active searching behaviours. Applying our model to Pacific skipjack tuna (Katsuwonus pelamis), we show that it accurately replicates the evolution of density distribution simulated by SEAPODYM with low time-mean error and a spatial correlation of density that exceeds 0.96 at all times. We demonstrate how the Lagrangian approach permits easy tracking of individuals' trajectories for examining connectivity between different regions, and show how the model can provide independent estimates of transfer rates between commonly used assessment regions. In particular, we find that retention rates in most assessment regions are considerably smaller (up to a factor of 2) than those estimated by this population of skipjack's primary assessment model. Moreover, these rates are sensitive to ocean state (e.g. El Nino vs La Nina) and so assuming fixed transfer rates between regions may lead to spurious stock estimates. A novel feature of the Lagrangian approach is that individual schools can be tracked through time, and we demonstrate that movement between two assessment regions at broad temporal scales includes extended transits through other regions at finer-scales. Finally, we discuss the utility of this modeling framework for the management of marine reserves, designing effective monitoring programmes, and exploring hypotheses regarding the behaviour of hard-to-observe oceanic animals.

Cardiac interbeat interval dynamics from childhood to senescence : comparison of conventional and new measures based on fractals and chaos theory

NASA Technical Reports Server (NTRS)

Pikkujamsa, S. M.; Makikallio, T. H.; Sourander, L. B.; Raiha, I. J.; Puukka, P.; Skytta, J.; Peng, C. K.; Goldberger, A. L.; Huikuri, H. V.

1999-01-01

BACKGROUND: New methods of R-R interval variability based on fractal scaling and nonlinear dynamics ("chaos theory") may give new insights into heart rate dynamics. The aims of this study were to (1) systematically characterize and quantify the effects of aging from early childhood to advanced age on 24-hour heart rate dynamics in healthy subjects; (2) compare age-related changes in conventional time- and frequency-domain measures with changes in newly derived measures based on fractal scaling and complexity (chaos) theory; and (3) further test the hypothesis that there is loss of complexity and altered fractal scaling of heart rate dynamics with advanced age. METHODS AND RESULTS: The relationship between age and cardiac interbeat (R-R) interval dynamics from childhood to senescence was studied in 114 healthy subjects (age range, 1 to 82 years) by measurement of the slope, beta, of the power-law regression line (log power-log frequency) of R-R interval variability (10(-4) to 10(-2) Hz), approximate entropy (ApEn), short-term (alpha(1)) and intermediate-term (alpha(2)) fractal scaling exponents obtained by detrended fluctuation analysis, and traditional time- and frequency-domain measures from 24-hour ECG recordings. Compared with young adults (<40 years old, n=29), children (<15 years old, n=27) showed similar complexity (ApEn) and fractal correlation properties (alpha(1), alpha(2), beta) of R-R interval dynamics despite lower spectral and time-domain measures. Progressive loss of complexity (decreased ApEn, r=-0.69, P<0.001) and alterations of long-term fractal-like heart rate behavior (increased alpha(2), r=0.63, decreased beta, r=-0.60, P<0.001 for both) were observed thereafter from middle age (40 to 60 years, n=29) to old age (>60 years, n=29). CONCLUSIONS: Cardiac interbeat interval dynamics change markedly from childhood to old age in healthy subjects. Children show complexity and fractal correlation properties of R-R interval time series comparable to those of young adults, despite lower overall heart rate variability. Healthy aging is associated with R-R interval dynamics showing higher regularity and altered fractal scaling consistent with a loss of complex variability.

A Review of Avian Monitoring and Mitigation Information at Existing Utility-Scale Solar Facilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walston, Leroy J.; Rollins, Katherine E.; Smith, Karen P.

2015-01-01

There are two basic types of solar energy technology: photovoltaic and concentrating solar power. As the number of utility-scale solar energy facilities using these technologies is expected to increase in the United States, so are the potential impacts on wildlife and their habitats. Recent attention is on the risk of fatality to birds. Understanding the current rates of avian mortality and existing monitoring requirements is an important first step in developing science-based mitigation and minimization protocols. The resulting information also allows a comparison of the avian mortality rates of utility-scale solar energy facilities with those from other technologies and sources,more » as well as the identification of data gaps and research needs. This report will present and discuss the current state of knowledge regarding avian issues at utility-scale solar energy facilities.« less

Bridging the Measurement Gap Between Research and Clinical Care in Schizophrenia: Positive and Negative Syndrome Scale-6 (PANSS-6) and Other Assessments Based on the Simplified Negative and Positive Symptoms Interview (SNAPSI).

PubMed

Østergaard, Søren D; Opler, Mark G A; Correll, Christoph U

2017-12-01

There is currently a "measurement gap" between research and clinical care in schizophrenia. The main reason behind this gap is that the most widely used rating scale in schizophrenia research, the 30-item Positive and Negative Syndrome Scale (PANSS), takes so long to administer that it is rarely used in clinical practice. This compromises the translation of research findings into clinical care and vice versa. The aim of this paper is to discuss how this measurement gap can be closed. Specifically, the main points of discussion are 1) the practical problems associated with using the full 30-item PANSS in clinical practice; 2) how the brief, six-item version of the Positive and Negative Syndrome Scale (PANSS-6) was derived empirically from the full 30-item PANSS and what the initial results obtained with PANSS-6 entail; and 3) how PANSS-6 ratings, guided by the newly developed, 15-25-minute, stand-alone Simplified Negative and Positive Symptoms Interview (SNAPSI), might help bridge the measurement gap between research and clinical care in schizophrenia. The full 30-item PANSS is often used in research studies, but is too time consuming to allow for routine clinical use. Recent studies suggest that the much briefer PANSS-6 is a psychometrically valid measure of core positive and negative symptoms of schizophrenia and that the scale is sensitive to symptom improvement following pharmacological treatment. SNAPSI is a brief interview that yields the information needed to rate PANSS-6 (and other brief rating scales). We believe that PANSS-6 ratings guided by SNAPSI will help bridge the measurement gap between research and clinical care in schizophrenia.

Multi-Scale Effects in the Strength of Ceramics

PubMed Central

Cook, Robert F.

2016-01-01

Multiple length-scale effects are demonstrated in indentation-strength measurements of a range of ceramic materials under inert and reactive conditions. Meso-scale effects associated with flaw disruption by lateral cracking at large indentation loads are shown to increase strengths above the ideal indentation response. Micro-scale effects associated with toughening by microstructural restraints at small indentation loads are shown to decrease strengths below the ideal response. A combined meso-micro-scale analysis is developed that describes ceramic inert strength behaviors over the complete indentation flaw size range. Nano-scale effects associated with chemical equilibria and crack velocity thresholds are shown to lead to invariant minimum strengths at slow applied stressing rates under reactive conditions. A combined meso-micro-nano-scale analysis is developed that describes the full range of reactive and inert strength behaviors as a function of indentation load and applied stressing rate. Applications of the multi-scale analysis are demonstrated for materials design, materials selection, toughness determination, crack velocity determination, bond-rupture parameter determination, and prediction of reactive strengths. The measurements and analysis provide strong support for the existence of sharp crack tips in ceramics such that the nano-scale mechanisms of discrete bond rupture are separate from the larger scale crack driving force mechanics characterized by continuum-based stress-intensity factors. PMID:27563150

Effects of forcing time scale on the simulated turbulent flows and turbulent collision statistics of inertial particles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rosa, B., E-mail: bogdan.rosa@imgw.pl; Parishani, H.; Department of Earth System Science, University of California, Irvine, California 92697-3100

2015-01-15

In this paper, we study systematically the effects of forcing time scale in the large-scale stochastic forcing scheme of Eswaran and Pope [“An examination of forcing in direct numerical simulations of turbulence,” Comput. Fluids 16, 257 (1988)] on the simulated flow structures and statistics of forced turbulence. Using direct numerical simulations, we find that the forcing time scale affects the flow dissipation rate and flow Reynolds number. Other flow statistics can be predicted using the altered flow dissipation rate and flow Reynolds number, except when the forcing time scale is made unrealistically large to yield a Taylor microscale flow Reynoldsmore » number of 30 and less. We then study the effects of forcing time scale on the kinematic collision statistics of inertial particles. We show that the radial distribution function and the radial relative velocity may depend on the forcing time scale when it becomes comparable to the eddy turnover time. This dependence, however, can be largely explained in terms of altered flow Reynolds number and the changing range of flow length scales present in the turbulent flow. We argue that removing this dependence is important when studying the Reynolds number dependence of the turbulent collision statistics. The results are also compared to those based on a deterministic forcing scheme to better understand the role of large-scale forcing, relative to that of the small-scale turbulence, on turbulent collision of inertial particles. To further elucidate the correlation between the altered flow structures and dynamics of inertial particles, a conditional analysis has been performed, showing that the regions of higher collision rate of inertial particles are well correlated with the regions of lower vorticity. Regions of higher concentration of pairs at contact are found to be highly correlated with the region of high energy dissipation rate.« less

Bifactor and Item Response Theory Analyses of Interviewer Report Scales of Cognitive Impairment in Schizophrenia

ERIC Educational Resources Information Center

Reise, Steven P.; Ventura, Joseph; Keefe, Richard S. E.; Baade, Lyle E.; Gold, James M.; Green, Michael F.; Kern, Robert S.; Mesholam-Gately, Raquelle; Nuechterlein, Keith H.; Seidman, Larry J.; Bilder, Robert

2011-01-01

A psychometric analysis of 2 interview-based measures of cognitive deficits was conducted: the 21-item Clinical Global Impression of Cognition in Schizophrenia (CGI-CogS; Ventura et al., 2008), and the 20-item Schizophrenia Cognition Rating Scale (SCoRS; Keefe et al., 2006), which were administered on 2 occasions to a sample of people with…

Cognitive Profiles in Youth with Autism Spectrum Disorder: An Investigation of Base Rate Discrepancies Using the Differential Ability Scales-Second Edition

ERIC Educational Resources Information Center

Nowell, Kerri P.; Schanding, G. Thomas, Jr.; Kanne, Stephen M.; Goin-Kochel, Robin P.

2015-01-01

Extant data suggest that the cognitive profiles of individuals with ASD may be characterized by variability, particularly in terms of verbal intellectual functioning (VIQ) and non-verbal intellectual functioning (NVIQ) discrepancies. The "Differential Ability Scales, Second Edition" (DAS-II) has limited data available on its use with…

Development and validation of the Spanish-English Language Proficiency Scale (SELPS).

PubMed

Smyk, Ekaterina; Restrepo, M Adelaida; Gorin, Joanna S; Gray, Shelley

2013-07-01

This study examined the development and validation of a criterion-referenced Spanish-English Language Proficiency Scale (SELPS) that was designed to assess the oral language skills of sequential bilingual children ages 4-8. This article reports results for the English proficiency portion of the scale. The SELPS assesses syntactic complexity, grammatical accuracy, verbal fluency, and lexical diversity based on 2 story retell tasks. In Study 1, 40 children were given 2 story retell tasks to evaluate the reliability of parallel forms. In Study 2, 76 children participated in the validation of the scale against language sample measures and teacher ratings of language proficiency. Study 1 indicated no significant differences between the SELPS scores on the 2 stories. Study 2 indicated that the SELPS scores correlated significantly with their counterpart language sample measures. Correlations between the SELPS and teacher ratings were moderate. The 2 story retells elicited comparable SELPS scores, providing a valuable tool for test-retest conditions in the assessment of language proficiency. Correlations between the SELPS scores and external variables indicated that these measures assessed the same language skills. Results provided empirical evidence regarding the validity of inferences about language proficiency based on the SELPS score.

Chlorine hazard evaluation for the zinc-chlorine electric vehicle battery. Final technical report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zalosh, R.G.; Bajpai, S.N.; Short, T.P.

1980-04-01

An evaluation of the hazards associated with conceivable accidental chlorine releases from zinc-chlorine electric vehicle batteries is presented. Since commercial batteries are not yet available, this hazard assessment is based both on theoretical chlorine dispersion models and small-scale and large-scale spill tests with chlorine hydrate. Six spill tests involving chlorine hydrate indicate that the danger zone in which chlorine vapor concentrations intermittently exceed 100 ppM extends at least 23 m directly downwind of a spill onto a warm road surface. Chlorine concentration data from the hydrate spill tests compare favorably with calculations based on a quasi-steady area source dispersion modelmore » and empirical estimates of the hydrate decomposition rate. The theoretical dispersion model has been combined with assumed hydrate spill probabilities and current motor vehicle accident statistics in order to project expected chlorine-induced fatality rates. These calculations indicate that expected chlorine fatality rates are several times higher in a city with a warm and calm climate than in a colder and windier city. Calculated chlorine-induced fatality rate projections for various climates are presented as a function of hydrate spill probability in order to illustrate the degree of vehicle/battery crashworthiness required to maintain chlorine-induced fatality rates below current vehicle fatility rates due to fires and asphyxiations.« less

Individual Differences in Base Rate Neglect: A Fuzzy Processing Preference Index

PubMed Central

Wolfe, Christopher R.; Fisher, Christopher R.

2013-01-01

Little is known about individual differences in integrating numeric base-rates and qualitative text in making probability judgments. Fuzzy-Trace Theory predicts a preference for fuzzy processing. We conducted six studies to develop the FPPI, a reliable and valid instrument assessing individual differences in this fuzzy processing preference. It consists of 19 probability estimation items plus 4 "M-Scale" items that distinguish simple pattern matching from “base rate respect.” Cronbach's Alpha was consistently above 0.90. Validity is suggested by significant correlations between FPPI scores and three other measurers: "Rule Based" Process Dissociation Procedure scores; the number of conjunction fallacies in joint probability estimation; and logic index scores on syllogistic reasoning. Replicating norms collected in a university study with a web-based study produced negligible differences in FPPI scores, indicating robustness. The predicted relationships between individual differences in base rate respect and both conjunction fallacies and syllogistic reasoning were partially replicated in two web-based studies. PMID:23935255

Study of neutron generation in the compact tokamak TUMAN-3M in support of a tokamak-based fusion neutron source

NASA Astrophysics Data System (ADS)

Kornev, V. A.; Askinazi, L. G.; Belokurov, A. A.; Chernyshev, F. V.; Lebedev, S. V.; Melnik, A. D.; Shabelsky, A. A.; Tukachinsky, A. S.; Zhubr, N. A.

2017-12-01

The paper presents DD neutron flux measurements in neutron beam injection (NBI) experiments aimed at the optimization of target plasma and heating beam parameters to achieve maximum neutron flux in the TUMAN-3M compact tokamak. Two ion sources of different design were used, which allowed the separation of the beam’s energy and power influence on the neutron rate. Using the database of experiments performed with the two ion sources, an empirical scaling was derived describing the neutron rate dependence on the target plasma and heating beam parameters. Numerical modeling of the neutron rate in the NBI experiments performed using the ASTRA transport code showed good agreement with the scaling.

Large Field of View PIV Measurements of Air Entrainment by SLS SMAT Water Sound Suppression System

NASA Astrophysics Data System (ADS)

Stegmeir, Matthew; Pothos, Stamatios; Bissell, Dan

2015-11-01

Water-based sound suppressions systems have been used to reduce the acoustic impact of space vehicle launches. Water flows at a high rate during launch in order to suppress Engine Generated Acoustics and other potentially damaging sources of noise. For the Space Shuttle, peak flow rates exceeded 900,000 gallons per minute. Such large water flow rates have the potential to induce substantial entrainment of the surrounding air, affecting the launch conditions and generating airflow around the launch vehicle. Validation testing is necessary to quantify this impact for future space launch systems. In this study, PIV measurements were performed to map the flow field above the SMAT sub-scale launch vehicle scaled launch stand. Air entrainment effects generated by a water-based sound suppression system were studied. Mean and fluctuating fluid velocities were mapped up to 1m above the test stand deck and compared to simulation results. Measurements performed with NASA MSFC.

Computation of infrared cooling rates in the water vapor bands

NASA Technical Reports Server (NTRS)

Chou, M. D.; Arking, A.

1978-01-01

A fast but accurate method for calculating the infrared radiative terms due to water vapor has been developed. It makes use of the far wing approximation to scale transmission along an inhomogeneous path to an equivalent homogeneous path. Rather than using standard conditions for scaling, the reference temperatures and pressures are chosen in this study to correspond to the regions where cooling is most significant. This greatly increased the accuracy of the new method. Compared to line by line calculations, the new method has errors up to 4% of the maximum cooling rate, while a commonly used method based upon the Goody band model (Rodgers and Walshaw, 1966) introduces errors up to 11%. The effect of temperature dependence of transmittance has also been evaluated; the cooling rate errors range up to 11% when the temperature dependence is ignored. In addition to being more accurate, the new method is much faster than those based upon the Goody band model.

Development and initial validation of primary care provider mental illness management and team-based care self-efficacy scales.

PubMed

Loeb, Danielle F; Crane, Lori A; Leister, Erin; Bayliss, Elizabeth A; Ludman, Evette; Binswanger, Ingrid A; Kline, Danielle M; Smith, Meredith; deGruy, Frank V; Nease, Donald E; Dickinson, L Miriam

Develop and validate self-efficacy scales for primary care provider (PCP) mental illness management and team-based care participation. We developed three self-efficacy scales: team-based care (TBC), mental illness management (MIM), and chronic medical illness (CMI). We developed the scales using Bandura's Social Cognitive Theory as a guide. The survey instrument included items from previously validated scales on team-based care and mental illness management. We administered a mail survey to 900 randomly selected Colorado physicians. We conducted exploratory principal factor analysis with oblique rotation. We constructed self-efficacy scales and calculated standardized Cronbach's alpha coefficients to test internal consistency. We calculated correlation coefficients between the MIM and TBC scales and previously validated measures related to each scale to evaluate convergent validity. We tested correlations between the TBC and the measures expected to correlate with the MIM scale and vice versa to evaluate discriminant validity. PCPs (n=402, response rate=49%) from diverse practice settings completed surveys. Items grouped into factors as expected. Cronbach's alphas were 0.94, 0.88, and 0.83 for TBC, MIM, and CMI scales respectively. In convergent validity testing, the TBC scale was correlated as predicted with scales assessing communications strategies, attitudes toward teams, and other teamwork indicators (r=0.25 to 0.40, all statistically significant). Likewise, the MIM scale was significantly correlated with several items about knowledge and experience managing mental illness (r=0.24 to 41, all statistically significant). As expected in discriminant validity testing, the TBC scale had only very weak correlations with the mental illness knowledge and experience managing mental illness items (r=0.03 to 0.12). Likewise, the MIM scale was only weakly correlated with measures of team-based care (r=0.09 to.17). This validation study of MIM and TBC self-efficacy scales showed high internal validity and good construct validity. Copyright © 2016 Elsevier Inc. All rights reserved.

Predicting and interpreting identification errors in military vehicle training using multidimensional scaling.

PubMed

Bohil, Corey J; Higgins, Nicholas A; Keebler, Joseph R

2014-01-01

We compared methods for predicting and understanding the source of confusion errors during military vehicle identification training. Participants completed training to identify main battle tanks. They also completed card-sorting and similarity-rating tasks to express their mental representation of resemblance across the set of training items. We expected participants to selectively attend to a subset of vehicle features during these tasks, and we hypothesised that we could predict identification confusion errors based on the outcomes of the card-sort and similarity-rating tasks. Based on card-sorting results, we were able to predict about 45% of observed identification confusions. Based on multidimensional scaling of the similarity-rating data, we could predict more than 80% of identification confusions. These methods also enabled us to infer the dimensions receiving significant attention from each participant. This understanding of mental representation may be crucial in creating personalised training that directs attention to features that are critical for accurate identification. Participants completed military vehicle identification training and testing, along with card-sorting and similarity-rating tasks. The data enabled us to predict up to 84% of identification confusion errors and to understand the mental representation underlying these errors. These methods have potential to improve training and reduce identification errors leading to fratricide.

Study of Rapid-Regression Liquefying Hybrid Rocket Fuels

NASA Technical Reports Server (NTRS)

Zilliac, Greg; DeZilwa, Shane; Karabeyoglu, M. Arif; Cantwell, Brian J.; Castellucci, Paul

2004-01-01

A report describes experiments directed toward the development of paraffin-based hybrid rocket fuels that burn at regression rates greater than those of conventional hybrid rocket fuels like hydroxyl-terminated butadiene. The basic approach followed in this development is to use materials such that a hydrodynamically unstable liquid layer forms on the melting surface of a burning fuel body. Entrainment of droplets from the liquid/gas interface can substantially increase the rate of fuel mass transfer, leading to surface regression faster than can be achieved using conventional fuels. The higher regression rate eliminates the need for the complex multi-port grain structures of conventional solid rocket fuels, making it possible to obtain acceptable performance from single-port structures. The high-regression-rate fuels contain no toxic or otherwise hazardous components and can be shipped commercially as non-hazardous commodities. Among the experiments performed on these fuels were scale-up tests using gaseous oxygen. The data from these tests were found to agree with data from small-scale, low-pressure and low-mass-flux laboratory tests and to confirm the expectation that these fuels would burn at high regression rates, chamber pressures, and mass fluxes representative of full-scale rocket motors.

An Experimental Study on Burning Characteristics of n-Heptane/Ethanol Mixture Pool Fires in a Reduced Scaled Tunnel

NASA Astrophysics Data System (ADS)

Yozgatligil, Ahmet; Shafee, Sina

2016-11-01

Fire accidents in recent decades have drawn attention to safety issues associated with the design, construction and maintenance of tunnels. A reduced scale tunnel model constructed based on Froude scaling technique is used in the current work. Mixtures of n-heptane and ethanol are burned with ethanol volumetric fraction up to 30 percent and the longitudinal ventilation velocity varying from 0.5 to 2.5 m/s. The burning rates of the pool fires are measured using a precision load cell. The heat release rates of the fires are calculated according to oxygen calorimetry method and the temperature distributions inside the tunnel are also measured. Results of the experiments show that the ventilation velocity variation has a significant effect on the pool fire burning rate, smoke temperature and the critical ventilation velocity. With increased oxygen depletion in case of increased ethanol content of blended pool fires, the quasi-steady heat release rate values tend to increase as well as the ceiling temperatures while the combustion duration decreases.

Comparison of NASA-TLX scale, Modified Cooper-Harper scale and mean inter-beat interval as measures of pilot mental workload during simulated flight tasks.

PubMed

Mansikka, Heikki; Virtanen, Kai; Harris, Don

2018-04-30

The sensitivity of NASA-TLX scale, modified Cooper-Harper (MCH) scale and the mean inter-beat interval (IBI) of successive heart beats, as measures of pilot mental workload (MWL), were evaluated in a flight training device (FTD). Operational F/A-18C pilots flew instrument approaches with varying task loads. Pilots' performance, subjective MWL ratings and IBI were measured. Based on the pilots' performance, three performance categories were formed; high-, medium- and low-performance. Values of the subjective rating scales and IBI were compared between categories. It was found that all measures were able to differentiate most task conditions and there was a strong, positive correlation between NASA-TLX and MCH scale. An explicit link between IBI, NASA-TLX, MCH and performance was demonstrated. While NASA-TLX, MCH and IBI have all been previously used to measure MWL, this study is the first one to investigate their association in a modern FTD, using a realistic flying mission and operational pilots.

Map visualization of groundwater withdrawals at the sub-basin scale

NASA Astrophysics Data System (ADS)

Goode, Daniel J.

2016-06-01

A simple method is proposed to visualize the magnitude of groundwater withdrawals from wells relative to user-defined water-resource metrics. The map is solely an illustration of the withdrawal magnitudes, spatially centered on wells—it is not capture zones or source areas contributing recharge to wells. Common practice is to scale the size (area) of withdrawal well symbols proportional to pumping rate. Symbols are drawn large enough to be visible, but not so large that they overlap excessively. In contrast to such graphics-based symbol sizes, the proposed method uses a depth-rate index (length per time) to visualize the well withdrawal rates by volumetrically consistent areas, called "footprints". The area of each individual well's footprint is the withdrawal rate divided by the depth-rate index. For example, the groundwater recharge rate could be used as a depth-rate index to show how large withdrawals are relative to that recharge. To account for the interference of nearby wells, composite footprints are computed by iterative nearest-neighbor distribution of excess withdrawals on a computational and display grid having uniform square cells. The map shows circular footprints at individual isolated wells and merged footprint areas where wells' individual footprints overlap. Examples are presented for depth-rate indexes corresponding to recharge, to spatially variable stream baseflow (normalized by basin area), and to the average rate of water-table decline (scaled by specific yield). These depth-rate indexes are water-resource metrics, and the footprints visualize the magnitude of withdrawals relative to these metrics.

Map visualization of groundwater withdrawals at the sub-basin scale

USGS Publications Warehouse

Goode, Daniel J.

2016-01-01

A simple method is proposed to visualize the magnitude of groundwater withdrawals from wells relative to user-defined water-resource metrics. The map is solely an illustration of the withdrawal magnitudes, spatially centered on wells—it is not capture zones or source areas contributing recharge to wells. Common practice is to scale the size (area) of withdrawal well symbols proportional to pumping rate. Symbols are drawn large enough to be visible, but not so large that they overlap excessively. In contrast to such graphics-based symbol sizes, the proposed method uses a depth-rate index (length per time) to visualize the well withdrawal rates by volumetrically consistent areas, called “footprints”. The area of each individual well’s footprint is the withdrawal rate divided by the depth-rate index. For example, the groundwater recharge rate could be used as a depth-rate index to show how large withdrawals are relative to that recharge. To account for the interference of nearby wells, composite footprints are computed by iterative nearest-neighbor distribution of excess withdrawals on a computational and display grid having uniform square cells. The map shows circular footprints at individual isolated wells and merged footprint areas where wells’ individual footprints overlap. Examples are presented for depth-rate indexes corresponding to recharge, to spatially variable stream baseflow (normalized by basin area), and to the average rate of water-table decline (scaled by specific yield). These depth-rate indexes are water-resource metrics, and the footprints visualize the magnitude of withdrawals relative to these metrics.

Gender-, age-, and race/ethnicity-based differential item functioning analysis of the movement disorder society-sponsored revision of the Unified Parkinson's disease rating scale.

PubMed

Goetz, Christopher G; Liu, Yuanyuan; Stebbins, Glenn T; Wang, Lu; Tilley, Barbara C; Teresi, Jeanne A; Merkitch, Douglas; Luo, Sheng

2016-12-01

Assess MDS-UPDRS items for gender-, age-, and race/ethnicity-based differential item functioning. Assessing differential item functioning is a core rating scale validation step. For the MDS-UPDRS, differential item functioning occurs if item-score probability among people with similar levels of parkinsonism differ according to selected covariates (gender, age, race/ethnicity). If the magnitude of differential item functioning is clinically relevant, item-score interpretation must consider influences by these covariates. Differential item functioning can be nonuniform (covariate variably influences an item-score across different levels of parkinsonism) or uniform (covariate influences an item-score consistently over all levels of parkinsonism). Using the MDS-UPDRS translation database of more than 5,000 PD patients from 14 languages, we tested gender-, age-, and race/ethnicity-based differential item functioning. To designate an item as having clinically relevant differential item functioning, we required statistical confirmation by 2 independent methods, along with a McFadden pseudo-R 2 magnitude statistic greater than "negligible." Most items showed no gender-, age- or race/ethnicity-based differential item functioning. When differential item functioning was identified, the magnitude statistic was always in the "negligible" range, and the scale-level impact was minimal. The absence of clinically relevant differential item functioning across all items and all parts of the MDS-UPDRS is strong evidence that the scale can be used confidently. As studies of Parkinson's disease increasingly involve multinational efforts and the MDS-UPDRS has several validated non-English translations, the findings support the scale's broad applicability in populations with varying gender, age, and race/ethnicity distributions. © 2016 International Parkinson and Movement Disorder Society. © 2016 International Parkinson and Movement Disorder Society.

Development and validation of the simulation-based learning evaluation scale.

PubMed

Hung, Chang-Chiao; Liu, Hsiu-Chen; Lin, Chun-Chih; Lee, Bih-O

2016-05-01

The instruments that evaluate a student's perception of receiving simulated training are English versions and have not been tested for reliability or validity. The aim of this study was to develop and validate a Chinese version Simulation-Based Learning Evaluation Scale (SBLES). Four stages were conducted to develop and validate the SBLES. First, specific desired competencies were identified according to the National League for Nursing and Taiwan Nursing Accreditation Council core competencies. Next, the initial item pool was comprised of 50 items related to simulation that were drawn from the literature of core competencies. Content validity was established by use of an expert panel. Finally, exploratory factor analysis and confirmatory factor analysis were conducted for construct validity, and Cronbach's coefficient alpha determined the scale's internal consistency reliability. Two hundred and fifty students who had experienced simulation-based learning were invited to participate in this study. Two hundred and twenty-five students completed and returned questionnaires (response rate=90%). Six items were deleted from the initial item pool and one was added after an expert panel review. Exploratory factor analysis with varimax rotation revealed 37 items remaining in five factors which accounted for 67% of the variance. The construct validity of SBLES was substantiated in a confirmatory factor analysis that revealed a good fit of the hypothesized factor structure. The findings tally with the criterion of convergent and discriminant validity. The range of internal consistency for five subscales was .90 to .93. Items were rated on a 5-point scale from 1 (strongly disagree) to 5 (strongly agree). The results of this study indicate that the SBLES is valid and reliable. The authors recommend that the scale could be applied in the nursing school to evaluate the effectiveness of simulation-based learning curricula. Copyright © 2016 Elsevier Ltd. All rights reserved.

Evaluation of coral reef carbonate production models at a global scale

NASA Astrophysics Data System (ADS)

Jones, N. S.; Ridgwell, A.; Hendy, E. J.

2014-09-01

Calcification by coral reef communities is estimated to account for half of all carbonate produced in shallow water environments and more than 25% of the total carbonate buried in marine sediments globally. Production of calcium carbonate by coral reefs is therefore an important component of the global carbon cycle. It is also threatened by future global warming and other global change pressures. Numerical models of reefal carbonate production are essential for understanding how carbonate deposition responds to environmental conditions including future atmospheric CO2 concentrations, but these models must first be evaluated in terms of their skill in recreating present day calcification rates. Here we evaluate four published model descriptions of reef carbonate production in terms of their predictive power, at both local and global scales, by comparing carbonate budget outputs with independent estimates. We also compile available global data on reef calcification to produce an observation-based dataset for the model evaluation. The four calcification models are based on functions sensitive to combinations of light availability, aragonite saturation (Ωa) and temperature and were implemented within a specifically-developed global framework, the Global Reef Accretion Model (GRAM). None of the four models correlated with independent rate estimates of whole reef calcification. The temperature-only based approach was the only model output to significantly correlate with coral-calcification rate observations. The absence of any predictive power for whole reef systems, even when consistent at the scale of individual corals, points to the overriding importance of coral cover estimates in the calculations. Our work highlights the need for an ecosystem modeling approach, accounting for population dynamics in terms of mortality and recruitment and hence coral cover, in estimating global reef carbonate budgets. In addition, validation of reef carbonate budgets is severely hampered by limited and inconsistent methodology in reef-scale observations.

Aetiology for the covariation between combined type ADHD and reading difficulties in a family study: the role of IQ

PubMed Central

Cheung, Celeste H.M.; Wood, Alexis C.; Paloyelis, Yannis; Arias-Vasquez, Alejandro; Buitelaar, Jan K.; Franke, Barbara; Miranda, Ana; Mulas, Fernando; Rommelse, Nanda; Sergeant, Joseph A.; Sonuga-Barke, Edmund J.; Faraone, Stephen V.; Asherson, Philip; Kuntsi, Jonna

2012-01-01

Background Twin studies using both clinical and population-based samples suggest that the frequent co-occurrence of attention deficit hyperactivity disorder (ADHD) and reading ability/disability (RD) is largely driven by shared genetic influences. While both disorders are associated with lower IQ, recent twin data suggest that the shared genetic variability between reading difficulties and ADHD inattention symptoms is largely independent from genetic influences contributing to general cognitive ability. The current study aimed to extend the previous findings that were based on rating scale measures in a population sample by examining the generalizability of the findings to a clinical population, and by measuring reading difficulties both with a rating scale and with an objective task. We therefore investigated the familial relationships between ADHD, reading difficulties and IQ in a sample of individuals diagnosed with ADHD combined type, their siblings and control sibling pairs. Methods We ran multivariate familial models on data from 1789 individuals at ages 6 to 19. Reading difficulties were measured with both rating scale and an objective task. IQ was obtained using the Wechsler Intelligence Scales (WISC-III / WAIS-III). Results Significant phenotypic (0.2–0.4) and familial (0.3–0.5) correlations were observed among ADHD, reading difficulties and IQ. Yet 53% to 72% of the overlapping familial influences between ADHD and reading difficulties were not shared with IQ. Conclusions Our finding that familial influences shared with general cognitive ability, though present, do not account for the majority of the overlapping familial influences on ADHD and reading difficulties extends previous findings from a population-based study to a clinically-ascertained sample with combined type ADHD. PMID:22324316

Application of a flexible lattice Boltzmann method based simulation tool for modelling physico-chemical processes at different scales

NASA Astrophysics Data System (ADS)

Patel, Ravi A.; Perko, Janez; Jacques, Diederik

2017-04-01

Often, especially in the disciplines related to natural porous media, such as for example vadoze zone or aquifer hydrology or contaminant transport, the relevant spatial and temporal scales on which we need to provide information is larger than the scale where the processes actually occur. Usual techniques used to deal with these problems assume the existence of a REV. However, in order to understand the behavior on larger scales it is important to downscale the problem onto the relevant scale of the processes. Due to the limitations of resources (time, memory) the downscaling can only be made up to the certain lower scale. At this lower scale still several scales may co-exist - the scale which can be explicitly described and a scale which needs to be conceptualized by effective properties. Hence, models which are supposed to provide effective properties on relevant scales should therefor be flexible enough to represent complex pore-structure by explicit geometry on one side, and differently defined processes (e.g. by the effective properties) which emerge on lower scale. In this work we present the state-of-the-art lattice Boltzmann method based simulation tool applicable to advection-diffusion equation coupled to geochemical processes. The lattice Boltzmann transport solver can be coupled with an external geochemical solver which allows to account for a wide range of geochemical reaction networks through thermodynamic databases. The applicability to multiphase systems is ongoing. We provide several examples related to the calculation of an effective diffusion properties, permeability and effective reaction rate based on a continuum scale based on the pore scale geometry.

On the physics of unstable infiltration, seepage, and gravity drainage in partially saturated tuffs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Faybishenko, B.; Bodvarsson, G.S.; Salve, R.

2002-04-01

To improve understanding of the physics of dynamic instabilities in unsaturated flow processes within the Paintbrush nonwelded unit (PTn) and the middle nonlithophysal portion of the Tonopah Spring welded tuff unit (TSw) of Yucca Mountain, we analyzed data from a series of infiltration tests carried out at two sites (Alcove 4 and Alcove 6) in the Exploratory Studies Facility, using analytical and empirical functions. The analysis of infiltration rates measured at both sites showed three temporal scales of infiltration rate: (1) a macro-scale trend of overall decreasing flow, (2) a meso-scale trend of fast and slow motion exhibiting three-stage variationsmore » of the flow rate (decreasing, increasing, and [again] decreasing flow rate, as observed in soils in the presence of entrapped air), and (3) micro-scale (high frequency) fluctuations. Infiltration tests in the nonwelded unit at Alcove 4 indicate that this unit may effectively dampen episodic fast infiltration events; however, well-known Kostyakov, Horton, and Philip equations do not satisfactorily describe the observed trends of the infiltration rate. Instead, a Weibull distribution model can most accurately describe experimentally determined time trends of the infiltration rate. Infiltration tests in highly permeable, fractured, welded tuff at Alcove 6 indicate that the infiltration rate exhibits pulsation, which may have been caused by multiple threshold effects and water-air redistribution between fractures and matrix. The empirical relationships between the extrinsic seepage from fractures, matrix imbibition, and gravity drainage versus the infiltration rate, as well as scaling and self-similarity for the leading edge of the water front are the hallmark of the nonlinear dynamic processes in water flow under episodic infiltration through fractured tuff. Based on the analysis of experimental data, we propose a conceptual model of a dynamic fracture flow and fracture-matrix interaction in fractured tuff, incorporating the time dependent processes of water redistribution in the fracture-matrix system.« less

On the Assessment of Global Terrestrial Reference Frame Temporal Variations

NASA Astrophysics Data System (ADS)

Ampatzidis, Dimitrios; Koenig, Rolf; Zhu, Shengyuan

2015-04-01

Global Terrestrial Reference Frames (GTRFs) as the International Terrestrial Reference Frame (ITRF) provide reliable 4-D position information (3-D coordinates and their evolution through time). The given 3-D velocities play a significant role in precise position acquisition and are estimated from long term coordinate time series from the space-geodetic techniques DORIS, GNSS, SLR, and VLBI. GTRFs temporal evolution is directly connected with their internal stability: The more intense and inhomogeneous velocity field, the less stable TRF is derived. The assessment of the quality of the GTRF is mainly realized by comparing it to each individual technique's reference frame. E.g the comparison of GTRFs to SLR-only based TRF gives the sense of the ITRF stability with respect to the Geocenter and scale and their associated rates respectively. In addition, the comparison of ITRF to the VLBI-only based TRF can be used for the scale validation. However, till now there is not any specified methodology for the total assessment (in terms of origin, orientation and scale respectively) of the temporal evolution and GTRFs associated accuracy. We present a new alternative diagnostic tool for the assessment of GTRFs temporal evolution based on the well-known time-dependent Helmert type transformation formula (three shifts, three rotations and scale rates respectively). The advantage of the new methodology relies on the fact that it uses the full velocity field of the TRF and therefore all points not just the ones common to different techniques. It also examines simultaneously rates of origin, orientation and scale. The methodology is presented and implemented to the two existing GTRFs on the market (ITRF and DTRF which is computed from DGFI) , the results are discussed. The results also allow to compare directly each GTRF dynamic behavior. Furthermore, the correlations of the estimated parameters can also provide useful information to the proposed GTRFs assessment scheme.

Development of Depression Profile: a new psychometric instrument to selectively evaluate depressive symptoms based on the neurocircuitry theory.

PubMed

Faludi, Gábor; Gonda, Xenia; Kliment, Edit; Bekes, Vera; Mészáros, Veronika; Oláh, Attila

2010-06-01

Although we have several self-report instruments available to assess depression, they yield a composite score and thus do not allow for the differential examination of major symptom clusters associated with depression. However, such an instrument would be a useful tool in subtyping depression and selecting the most appropriate pharmacotherapy for each patient. The neurocircuitry theory describes the biochemical and neuroanatomic background associated with the major symptoms of depression. Based on the neurocircuitry theory, our team has developed a new instrument, the Depression Profile, to selectively assess depressive symptom clusters associated with different neurotransmitter systems and neuroanatomic structures. The aim of our study was to investigate the psychometric characteristics of Depression Profile. 339 patients consecutively admitted with DSM-IV major depression in our hospital completed the Depression Profile in the first two weeks of their hospitalisation. 81 patients in an adult outpatient unit also completed the Zung Self-rating Depression Scale. Internal consistency of Depression Profile was tested with item analysis. The external validity of Depression Profile against the Zung Self-rating Depression Scale was tested using Pearson correlations. The internal consistency of Depression Profile proved to be excellent. The Cronbach alpha values of the scales met the expectable minimum level derived from the number of items in the scales. In testing for convergent validity, all Pearson correlation coefficients between Depression profile subscales and the Zung Self-rating Depression Scale were significant and moderate to high which indicates the good external validity of our instrument. The initial psychometric evaluation of Depression Profile indicates that our instrument has good reliability and internal and external validity. The instrument also proved to be useful in clinical work to aid the choice of medications and determine the subtype of depressive episodes. Further studies, possibly with biochemical and neuroimaging methodology are needed to validate the 9 main symptom clusters of the Depression Profile subscales with respect to their neuroanatomical and neurochemical bases.

Cooling rate effects in sodium silicate glasses: Bridging the gap between molecular dynamics simulations and experiments

NASA Astrophysics Data System (ADS)

Li, Xin; Song, Weiying; Yang, Kai; Krishnan, N. M. Anoop; Wang, Bu; Smedskjaer, Morten M.; Mauro, John C.; Sant, Gaurav; Balonis, Magdalena; Bauchy, Mathieu

2017-08-01

Although molecular dynamics (MD) simulations are commonly used to predict the structure and properties of glasses, they are intrinsically limited to short time scales, necessitating the use of fast cooling rates. It is therefore challenging to compare results from MD simulations to experimental results for glasses cooled on typical laboratory time scales. Based on MD simulations of a sodium silicate glass with varying cooling rate (from 0.01 to 100 K/ps), here we show that thermal history primarily affects the medium-range order structure, while the short-range order is largely unaffected over the range of cooling rates simulated. This results in a decoupling between the enthalpy and volume relaxation functions, where the enthalpy quickly plateaus as the cooling rate decreases, whereas density exhibits a slower relaxation. Finally, we show that, using the proper extrapolation method, the outcomes of MD simulations can be meaningfully compared to experimental values when extrapolated to slower cooling rates.

Can low-resolution airborne laser scanning data be used to model stream rating curves?

USGS Publications Warehouse

Lyon, Steve; Nathanson, Marcus; Lam, Norris; Dahlke, Helen; Rutzinger, Martin; Kean, Jason W.; Laudon, Hjalmar

2015-01-01

This pilot study explores the potential of using low-resolution (0.2 points/m2) airborne laser scanning (ALS)-derived elevation data to model stream rating curves. Rating curves, which allow the functional translation of stream water depth into discharge, making them integral to water resource monitoring efforts, were modeled using a physics-based approach that captures basic geometric measurements to establish flow resistance due to implicit channel roughness. We tested synthetically thinned high-resolution (more than 2 points/m2) ALS data as a proxy for low-resolution data at a point density equivalent to that obtained within most national-scale ALS strategies. Our results show that the errors incurred due to the effect of low-resolution versus high-resolution ALS data were less than those due to flow measurement and empirical rating curve fitting uncertainties. As such, although there likely are scale and technical limitations to consider, it is theoretically possible to generate rating curves in a river network from ALS data of the resolution anticipated within national-scale ALS schemes (at least for rivers with relatively simple geometries). This is promising, since generating rating curves from ALS scans would greatly enhance our ability to monitor streamflow by simplifying the overall effort required.

Cosmogenic activation of germanium used for tonne-scale rare event search experiments

NASA Astrophysics Data System (ADS)

Wei, W.-Z.; Mei, D.-M.; Zhang, C.

2017-11-01

We report a comprehensive study of cosmogenic activation of germanium used for tonne-scale rare event search experiments. The germanium exposure to cosmic rays on the Earth's surface are simulated with and without a shielding container using Geant4 for a given cosmic muon, neutron, and proton energy spectrum. The production rates of various radioactive isotopes are obtained for different sources separately. We find that fast neutron induced interactions dominate the production rate of cosmogenic activation. Geant4-based simulation results are compared with the calculation of ACTIVIA and the available experimental data. A reasonable agreement between Geant4 simulations and several experimental data sets is presented. We predict that cosmogenic activation of germanium can set limits to the sensitivity of the next generation of tonne-scale experiments.

Extracorporeal CO2 removal by hemodialysis: in vitro model and feasibility.

PubMed

May, Alexandra G; Sen, Ayan; Cove, Matthew E; Kellum, John A; Federspiel, William J

2017-12-01

Critically ill patients with acute respiratory distress syndrome and acute exacerbations of chronic obstructive pulmonary disease often develop hypercapnia and require mechanical ventilation. Extracorporeal carbon dioxide removal can manage hypercarbia by removing carbon dioxide directly from the bloodstream. Respiratory hemodialysis uses traditional hemodialysis to remove CO 2 from the blood, mainly as bicarbonate. In this study, Stewart's approach to acid-base chemistry was used to create a dialysate that would maintain blood pH while removing CO 2 as well as determine the blood and dialysate flow rates necessary to remove clinically relevant CO 2 volumes. Bench studies were performed using a scaled down respiratory hemodialyzer in bovine or porcine blood. The scaling factor for the bench top experiments was 22.5. In vitro dialysate flow rates ranged from 2.2 to 24 mL/min (49.5-540 mL/min scaled up) and blood flow rates were set at 11 and 18.7 mL/min (248-421 mL/min scaled up). Blood inlet CO 2 concentrations were set at 50 and 100 mmHg. Results are reported as scaled up values. The CO 2 removal rate was highest at intermittent hemodialysis blood and dialysate flow rates. At an inlet pCO 2 of 50 mmHg, the CO 2 removal rate increased from 62.6 ± 4.8 to 77.7 ± 3 mL/min when the blood flow rate increased from 248 to 421 mL/min. At an inlet pCO 2 of 100 mmHg, the device was able to remove up to 117.8 ± 3.8 mL/min of CO 2 . None of the test conditions caused the blood pH to decrease, and increases were ≤0.08. When the bench top data is scaled up, the system removes a therapeutic amount of CO 2 standard intermittent hemodialysis flow rates. The zero bicarbonate dialysate did not cause acidosis in the post-dialyzer blood. These results demonstrate that, with further development, respiratory hemodialysis can be a minimally invasive extracorporeal carbon dioxide removal treatment option.

Construction and Validation of Parental Rating Scale from Children's Emotional Intelligence (4-8 Years Old)

ERIC Educational Resources Information Center

Kajbafnezhad, Hadi

2016-01-01

Emotional intelligence rating tools are not available for children, but mostly for children. So, the present study investigated the measurement and assessment of Emotional Intelligence in children with the age range of 4-8 years old by parents (mothers) through a preliminary research-made questionnaire. This study was based on an…

Standardized Observational Assessment of Attention Deficit Hyperactivity Disorder Combined and Predominantly Inattentive Subtypes. II. Classroom Observations

ERIC Educational Resources Information Center

McConaughy, Stephanie H.; Ivanova, Masha Y.; Antshel, Kevin; Eiraldi, Ricardo B.; Dumenci, Levent

2009-01-01

Trained classroom observers used the Direct Observation Form (DOF; McConaughy & Achenbach, 2009) to rate observations of 163 6- to 11-year-old children in their school classrooms. Participants were assigned to four groups based on a parent diagnostic interview and parent and teacher rating scales: Attention Deficit Hyperactivity Disorder…

Formative Assessment Using Direct Behavior Ratings: Evaluating Intervention Effects of Daily Behavior Report Cards

ERIC Educational Resources Information Center

Sims, Wesley A.; Riley-Tillman, Chris; Cohen, Daniel R.

2017-01-01

This study examined the treatment sensitivity of "Direct Behavior Rating-Single Item Scales" (DBR-SIS) in response to an evidence-based intervention delivered in a single-case, multiple-baseline design. DBR-SIS was used as a formative assessment in conjunction with a frequently used intervention in schools, a Daily Behavior Report Card…

Construction and evaluation of a self rating scale for stress-induced exhaustion disorder, the Karolinska Exhaustion Disorder Scale.

PubMed

Besèr, Aniella; Sorjonen, Kimmo; Wahlberg, Kristina; Peterson, Ulla; Nygren, Ake; Asberg, Marie

2014-02-01

Prolonged stress (≥ six months) may cause a condition which has been named exhaustion disorder (ED) with ICD-10 code F43.8. ED is characterised by exhaustion, cognitive problems, poor sleep and reduced tolerance to further stress. ED can cause long term disability and depressive symptoms may develop. The aim was to construct and evaluate a self-rating scale, the Karolinska Exhaustion Disorder Scale (KEDS), for the assessment of ED symptoms. A second aim was to examine the relationship between self-rated symptoms of ED, depression, and anxiety using KEDS and the Hospital Anxiety and Depression Scale (HAD). Items were selected based on their correspondence to criteria for ED as formulated by the Swedish National Board of Health and Welfare (NBHW), with seven response alternatives in a Likert-format. Self-ratings performed by 317 clinically assessed participants were used to analyse the scale's psychometric properties. KEDS consists of nine items with a scale range of 0-54. Receiver operating characteristics analysis demonstrated that a cut-off score of 19 was accompanied by high sensitivity and specificity (each above 95%) in the discrimination between healthy subjects and patients with ED. Reliability was satisfactory and confirmatory factor analysis revealed that ED, depression and anxiety are best regarded as different phenomena. KEDS may be a useful tool in the assessment of symptoms of Exhaustion Disorder in clinical as well as research settings. There is evidence that the symptom clusters of ED, anxiety and depression, respectively, reflect three different underlying dimensions. © 2013 The Authors. Scandinavian Journal of Psychology published by Scandinavian Psychological Associations and John Wiley & Sons Ltd.

Scaling behavior of online human activity

NASA Astrophysics Data System (ADS)

Zhao, Zhi-Dan; Cai, Shi-Min; Huang, Junming; Fu, Yan; Zhou, Tao

2012-11-01

The rapid development of the Internet technology enables humans to explore the web and record the traces of online activities. From the analysis of these large-scale data sets (i.e., traces), we can get insights about the dynamic behavior of human activity. In this letter, the scaling behavior and complexity of human activity in the e-commerce, such as music, books, and movies rating, are comprehensively investigated by using the detrended fluctuation analysis technique and the multiscale entropy method. Firstly, the interevent time series of rating behaviors of these three types of media show similar scaling properties with exponents ranging from 0.53 to 0.58, which implies that the collective behaviors of rating media follow a process embodying self-similarity and long-range correlation. Meanwhile, by dividing the users into three groups based on their activities (i.e., rating per unit time), we find that the scaling exponents of the interevent time series in the three groups are different. Hence, these results suggest that a stronger long-range correlations exist in these collective behaviors. Furthermore, their information complexities vary in the three groups. To explain the differences of the collective behaviors restricted to the three groups, we study the dynamic behavior of human activity at the individual level, and find that the dynamic behaviors of a few users have extremely small scaling exponents associated with long-range anticorrelations. By comparing the interevent time distributions of four representative users, we can find that the bimodal distributions may bring forth the extraordinary scaling behaviors. These results of the analysis of the online human activity in the e-commerce may not only provide insight into its dynamic behaviors but may also be applied to acquire potential economic interest.

Assessing the influence of rater and subject characteristics on measures of agreement for ordinal ratings.

PubMed

Nelson, Kerrie P; Mitani, Aya A; Edwards, Don

2017-09-10

Widespread inconsistencies are commonly observed between physicians' ordinal classifications in screening tests results such as mammography. These discrepancies have motivated large-scale agreement studies where many raters contribute ratings. The primary goal of these studies is to identify factors related to physicians and patients' test results, which may lead to stronger consistency between raters' classifications. While ordered categorical scales are frequently used to classify screening test results, very few statistical approaches exist to model agreement between multiple raters. Here we develop a flexible and comprehensive approach to assess the influence of rater and subject characteristics on agreement between multiple raters' ordinal classifications in large-scale agreement studies. Our approach is based upon the class of generalized linear mixed models. Novel summary model-based measures are proposed to assess agreement between all, or a subgroup of raters, such as experienced physicians. Hypothesis tests are described to formally identify factors such as physicians' level of experience that play an important role in improving consistency of ratings between raters. We demonstrate how unique characteristics of individual raters can be assessed via conditional modes generated during the modeling process. Simulation studies are presented to demonstrate the performance of the proposed methods and summary measure of agreement. The methods are applied to a large-scale mammography agreement study to investigate the effects of rater and patient characteristics on the strength of agreement between radiologists. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

ACCOUNTING FOR BIOLOGICAL AND ANTHROPOGENIC FACTORS IN NATIONAL LAND-BASED CARBON BUDGETS

EPA Science Inventory

Efforts to quantify net greenhouse gas emissions at the national scale, as required by the United Nations Framework Convention on Climate Change, must include both industrial emissions and the net flux associated with the land base. In this study, data on current land use, rates ...

Assessment in Performance-Based Secondary Music Classes

ERIC Educational Resources Information Center

Pellegrino, Kristen; Conway, Colleen M.; Russell, Joshua A.

2015-01-01

After sharing research findings about grading and assessment practices in secondary music ensemble classes, we offer examples of commonly used assessment tools (ratings scale, checklist, rubric) for the performance ensemble. Then, we explore the various purposes of assessment in performance-based music courses: (1) to meet state, national, and…

Exploring the Impact of Mental Workload on Rater-Based Assessments

ERIC Educational Resources Information Center

Tavares, Walter; Eva, Kevin W.

2013-01-01

When appraising the performance of others, assessors must acquire relevant information and process it in a meaningful way in order to translate it effectively into ratings, comments, or judgments about how well the performance meets appropriate standards. Rater-based assessment strategies in health professional education, including scale and…

Building lab-scale x-ray tube based irradiators

USDA-ARS?s Scientific Manuscript database

The construction of economical x-ray tube based irradiators in a variety of configurations is described using 1000 Watt x-ray tubes. Single tube, double tube, and four tube designs are described, as well as various cabinet construction techniques. Relatively high dose rates were achieved for small s...

Relationship between anxiety, anxiety sensitivity and conduct disorder symptoms in children and adolescents with attention-deficit/hyperactivity disorder (ADHD).

PubMed

Bilgiç, Ayhan; Türkoğlu, Serhat; Ozcan, Ozlem; Tufan, Ali Evren; Yılmaz, Savaş; Yüksel, Tuğba

2013-09-01

Attention-deficit hyperactivity disorder (ADHD) is often comorbid with anxiety disorders and previous studies observed that anxiety could have an impact on the clinical course of ADHD and comorbid disruptive behavioral disorders (conduct disorders and oppositional-defiant disorders). Anxiety sensitivity (AS) is a different concept from anxiety per se and it is believed to represent the constitutionally based sensitivity of individuals to anxiety and anxiety symptoms. We aimed to assess the associations between anxiety, AS and symptoms of disruptive behavioral disorders (DBD) in a clinical sample of children and adolescents with ADHD. The sample consisted of 274 treatment naive children with ADHD aged 8-17 years. The severity of ADHD symptoms and comorbid DBD were assessed via parent rated Turgay DSM-IV-Based Child and Adolescent Behavioral Disorders Screening and Rating Scale (T-DSM-IV-S), Conners' Parent Rating Scale (CPRS), and Conners' Teacher Rating Scale (CTRS). AS and severity of anxiety symptoms of children were evaluated by self-report inventories. The association between anxiety, AS, and DBD was evaluated using structural equation modeling. Analyses revealed that AS social subscale scores negatively predicted symptoms of conduct disorder (CD) reported in T-DSM-IV-S. On the other hand, CD symptoms positively predicted severity of anxiety. No direct relationships were detected between anxiety, AS and oppositional-defiant behavior scores in any scales. These results may suggest a protective effect of AS social area on the development of conduct disorder in the presence of a diagnosis of ADHD, while the presence of symptoms of CD may be a vulnerability factor for the development of anxiety symptoms in children and adolescents with ADHD.

False match elimination for face recognition based on SIFT algorithm

NASA Astrophysics Data System (ADS)

Gu, Xuyuan; Shi, Ping; Shao, Meide

2011-06-01

The SIFT (Scale Invariant Feature Transform) is a well known algorithm used to detect and describe local features in images. It is invariant to image scale, rotation and robust to the noise and illumination. In this paper, a novel method used for face recognition based on SIFT is proposed, which combines the optimization of SIFT, mutual matching and Progressive Sample Consensus (PROSAC) together and can eliminate the false matches of face recognition effectively. Experiments on ORL face database show that many false matches can be eliminated and better recognition rate is achieved.

Construction and evaluation of a self rating scale for stress-induced Exhaustion Disorder, the Karolinska Exhaustion Disorder Scale

PubMed Central

Besèr, Aniella; Sorjonen, Kimmo; Wahlberg, Kristina; Peterson, Ulla; Nygren, Åke; Åsberg, Marie

2014-01-01

Prolonged stress (≥ six months) may cause a condition which has been named exhaustion disorder (ED) with ICD-10 code F43.8. ED is characterised by exhaustion, cognitive problems, poor sleep and reduced tolerance to further stress. ED can cause long term disability and depressive symptoms may develop. The aim was to construct and evaluate a self-rating scale, the Karolinska Exhaustion Disorder Scale (KEDS), for the assessment of ED symptoms. A second aim was to examine the relationship between self-rated symptoms of ED, depression, and anxiety using KEDS and the Hospital Anxiety and Depression Scale (HAD). Items were selected based on their correspondence to criteria for ED as formulated by the Swedish National Board of Health and Welfare (NBHW), with seven response alternatives in a Likert-format. Self-ratings performed by 317 clinically assessed participants were used to analyse the scale’s psychometric properties. KEDS consists of nine items with a scale range of 0–54. Receiver operating characteristics analysis demonstrated that a cut-off score of 19 was accompanied by high sensitivity and specificity (each above 95%) in the discrimination between healthy subjects and patients with ED. Reliability was satisfactory and confirmatory factor analysis revealed that ED, depression and anxiety are best regarded as different phenomena. KEDS may be a useful tool in the assessment of symptoms of Exhaustion Disorder in clinical as well as research settings. There is evidence that the symptom clusters of ED, anxiety and depression, respectively, reflect three different underlying dimensions. PMID:24236500

Cross-cultural reliability and validity of ADHD assessed by the ADHD Rating Scale in a pan-European study.

PubMed

Döpfner, Manfred; Steinhausen, Hans-Christoph; Coghill, David; Dalsgaard, Søren; Poole, Lynne; Ralston, Stephen J; Rothenberger, Aribert

2006-12-01

To provide psychometric information on the Attention-Deficit/Hyperactivity Disorder (ADHD) Rating Scale-IV (ADHD-RS-IV) in a large population of children with ADHD. Patients aged 6-18 years (n=1,478 in baseline analysis) were rated by 244 physicians on the ADHD-RS-IV based on a semi-structured interview with the patient's parent. Physicians additionally rated functional impairment (CGAS) and health status (CGI-S), and parents rated their child's behavioural and emotional problems (SDQ) and quality of life (CHIP-CE). Inattention and hyperactivity-impulsivity as dimensions of ADHD were replicated. 3-factor solutions reflecting the ICD-10 definition, with hyperactivity, impulsivity and inattention as separate dimensions were extracted in some national sub-samples and in separate analyses for boys and younger children.Good internal consistencies, strong country effects and small effects of age were found. Based on ADHD-RS-IV, 88.5% of patients met the criteria for any ADHD diagnosis. Correlations between ADHD-RS-IV and measures of functional impairment were low but statistically significant. The correlations with SDQ and CHIP-CE scales confirm the convergent and divergent validity of ADHD-RS-IV. Impressive evidence for the cross-cultural factorial validity, internal consistency as well as convergent and divergent validity of ADHD-RS-IV was found. ADHD can be assessed reliably and validly in routine care across Europe. The ICD-10 3-factor model seems to be less robust than the DSM-IV 2-factor model, but may be a good description for special populations (boys, younger children).

The Educated Guess: Determining Drug Doses in Exotic Animals Using Evidence-Based Medicine.

PubMed

Visser, Marike; Oster, Seth C

2018-05-01

Lack of species-specific pharmacokinetic and pharmacodynamic data is a challenge for pharmaceutical and dose selection. If available, dose extrapolation can be accomplished via basic equations. If unavailable, several methods have been described. Linear scaling uses an established milligrams per kilograms dose based on weight. This does not allow for differences in species drug metabolism, sometimes resulting in toxicity. Allometric scaling correlates body weight and metabolic rate but fails for drugs with significant hepatic metabolism and cannot be extrapolated to avians or reptiles. Evidence-based veterinary medicine for dose design based on species similarity is discussed, considering physiologic differences between classes. Copyright © 2018 Elsevier Inc. All rights reserved.

Developing the Person-Environment Apathy Rating for persons with dementia.

PubMed

Jao, Ying-Ling; Algase, Donna L; Specht, Janet K; Williams, Kristine

2016-08-01

To develop the Person-Environment Apathy Rating (PEAR) scale that measures environmental stimulation and apathy in persons with dementia and to evaluate its psychometrics. The PEAR scale consists of the PEAR-Environment subscale and PEAR-Apathy subscales. The items were developed via literature review, field testing, expert review, and pilot testing. The construct validity and reliability were examined through video observation. The parent study enrolled 185 institutionalized residents with dementia. For this study, 96 videos were selected from 24 participants. The PEAR-Environment subscale was validated using the Ambiance Scale and the Crowding Index. The PEAR-Apathy subscale was validated using the Neuropsychiatric Inventory (NPI)-Apathy, Passivity in Dementia Scale (PDS), and NPI-Depression. The PEAR-Environment subscale and PEAR-Apathy subscales each consists of six items rated on a 1-4 scale. For validity, the Crowding Index slightly, yet significantly, correlated with the PEAR-Environment subscale total score and three of the individual scores. Ambiance Scale scores, both engaging and soothing, did not correlate with the PEAR-Environment subscale. The PEAR-Apathy highly correlated with the PDS and NPI-Apathy and moderately correlated with the NPI-Depression, suggesting good convergent validity and moderate discriminant validity. For reliability, both environment and apathy subscales demonstrated excellent internal consistency. Although facial expression and eye contact showed moderate inter-rater reliability, all other items showed good to excellent inter-rater and intra-rater reliability. This study has successfully developed the PEAR scale and established its psychometrics based on the compatible scales available. The PEAR scale is the first scale that concurrently assesses apathy and environmental stimulation, and is recommended for use in persons with dementia.

Thresholds of understanding: Exploring assumptions of scale invariance vs. scale dependence in global biogeochemical models

NASA Astrophysics Data System (ADS)

Wieder, W. R.; Bradford, M.; Koven, C.; Talbot, J. M.; Wood, S.; Chadwick, O.

2016-12-01

High uncertainty and low confidence in terrestrial carbon (C) cycle projections reflect the incomplete understanding of how best to represent biologically-driven C cycle processes at global scales. Ecosystem theories, and consequently biogeochemical models, are based on the assumption that different belowground communities function similarly and interact with the abiotic environment in consistent ways. This assumption of "Scale Invariance" posits that environmental conditions will change the rate of ecosystem processes, but the biotic response will be consistent across sites. Indeed, cross-site comparisons and global-scale analyses suggest that climate strongly controls rates of litter mass loss and soil organic matter turnover. Alternatively, activities of belowground communities are shaped by particular local environmental conditions, such as climate and edaphic conditions. Under this assumption of "Scale Dependence", relationships generated by evolutionary trade-offs in acquiring resources and withstanding environmental stress dictate the activities of belowground communities and their functional response to environmental change. Similarly, local edaphic conditions (e.g. permafrost soils or reactive minerals that physicochemically stabilize soil organic matter on mineral surfaces) may strongly constrain the availability of substrates that biota decompose—altering the trajectory of soil biogeochemical response to perturbations. Identifying when scale invariant assumptions hold vs. where local variation in biotic communities or edaphic conditions must be considered is critical to advancing our understanding and representation of belowground processes in the face of environmental change. Here we introduce data sets that support assumptions of scale invariance and scale dependent processes and discuss their application in global-scale biogeochemical models. We identify particular domains over which assumptions of scale invariance may be appropriate and potential thresholds where shifts in ecosystem function may be expected. Finally, we discuss the mechanistic insight that can be applied in process-based models and datasets that can evaluate models across spatial and temporal scales.

Determining 30-day readmission risk for heart failure patients: the Readmission After Heart Failure scale

PubMed Central

Chamberlain, Ronald S; Sond, Jaswinder; Mahendraraj, Krishnaraj; Lau, Christine SM; Siracuse, Brianna L

2018-01-01

Background Chronic heart failure (CHF), which affects >5 million Americans, accounts for >1 million hospitalizations annually. As a part of the Hospital Readmission Reduction Program, the Affordable Care Act requires that the Centers for Medicare and Medicaid Services reduce payments to hospitals with excess readmissions. This study sought to develop a scale that reliably predicts readmission rates among patients with CHF. Methods The State Inpatient Database (2006–2011) was utilized, and discharge data including demographic and clinical characteristics on 642,448 patients with CHF from California and New York (derivation cohort) and 365,359 patients with CHF from Florida and Washington (validation cohort) were extracted. The Readmission After Heart Failure (RAHF) scale was developed to predict readmission risk. Results The 30-day readmission rates were 9.42 and 9.17% (derivation and validation cohorts, respectively). Age <65 years, male gender, first income quartile, African American race, race other than African American or Caucasian, Medicare, Medicaid, self-pay/no insurance, drug abuse, renal failure, chronic pulmonary disorder, diabetes, depression, and fluid and electrolyte disorder were associated with higher readmission risk after hospitalization for CHF. The RAHF scale was created and explained the 95% of readmission variability within the validation cohort. The RAHF scale was then used to define the following three levels of risk for readmission: low (RAHF score <12; 7.58% readmission rate), moderate (RAHF score 12–15; 9.78% readmission rate), and high (RAHF score >15; 12.04% readmission rate). The relative risk of readmission was 1.67 for the high-risk group compared with the low-risk group. Conclusion The RAHF scale reliably predicts a patient’s 30-day CHF readmission risk based on demographic and clinical factors present upon initial admission. By risk-stratifying patients, using models such as the RAHF scale, strategies tailored to each patient can be implemented to improve patient outcomes and reduce health care costs. PMID:29670391

100-NR-2 Apatite Treatability Test: Fall 2010 Tracer Infiltration Test (White Paper)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vermeul, Vincent R.; Fritz, Brad G.; Fruchter, Jonathan S.

The primary objectives of the tracer infiltration test were to 1) determine whether field-scale hydraulic properties for the compacted roadbed materials and underlying Hanford fm. sediments comprising the zone of water table fluctuation beneath the site are consistent with estimates based laboratory-scale measurements on core samples and 2) characterize wetting front advancement and distribution of soil moisture achieved for the selected application rate. These primary objectives were met. The test successfully demonstrated that 1) the remaining 2 to 3 ft of compacted roadbed material below the infiltration gallery does not limit infiltration rates to levels that would be expected tomore » eliminate near surface application as a viable amendment delivery approach and 2) the combined aqueous and geophysical monitoring approaches employed at this site, with some operational adjustments based on lessons learned, provides an effective means of assessing wetting front advancement and the distribution of soil moisture achieved for a given solution application. Reasonably good agreement between predicted and observed tracer and moisture front advancement rates was observed. During the first tracer infiltration test, which used a solution application rate of 0.7 cm/hr, tracer arrivals were observed at the water table (10 to 12 ft below the bottom of the infiltration gallery) after approximately 5 days, for an advancement rate of approximately 2 ft/day. This advancement rate is generally consistent with pre-test modeling results that predicted tracer arrival at the water table after approximately 5 days (see Figure 8, bottom left panel). This agreement indicates that hydraulic property values specified in the model for the compacted roadbed materials and underlying Hanford formation sediments, which were based on laboratory-scale measurements, are reasonable estimates of actual field-scale conditions. Additional work is needed to develop a working relationship between resistivity change and the associated change in moisture content so that 4D images of moisture content change can be generated. Results from this field test will be available for any future Ca-citrate-PO4 amendment infiltration tests, which would be designed to evaluate the efficacy of using near surface application of amendments to form apatite mineral phases in the upper portion of the zone of water table fluctuation.« less

Improved collaborative filtering recommendation algorithm of similarity measure

NASA Astrophysics Data System (ADS)

Zhang, Baofu; Yuan, Baoping

2017-05-01

The Collaborative filtering recommendation algorithm is one of the most widely used recommendation algorithm in personalized recommender systems. The key is to find the nearest neighbor set of the active user by using similarity measure. However, the methods of traditional similarity measure mainly focus on the similarity of user common rating items, but ignore the relationship between the user common rating items and all items the user rates. And because rating matrix is very sparse, traditional collaborative filtering recommendation algorithm is not high efficiency. In order to obtain better accuracy, based on the consideration of common preference between users, the difference of rating scale and score of common items, this paper presents an improved similarity measure method, and based on this method, a collaborative filtering recommendation algorithm based on similarity improvement is proposed. Experimental results show that the algorithm can effectively improve the quality of recommendation, thus alleviate the impact of data sparseness.

Assessment of anxiety symptoms in school children: a cross-sex and ethnic examination.

PubMed

Holly, Lindsay E; Little, Michelle; Pina, Armando A; Caterino, Linda C

2015-02-01

We evaluated the cross-sex and -ethnic (Hispanic/Latino, non-Hispanic White) measurement invariance of anxiety symptoms based on the Spence Children's Anxiety Scale (SCAS) as well as SCAS anxiety symptoms' correspondence with scores on the 5-item Screen for Child Anxiety Related Emotional Disorders (SCARED) and teacher ratings of child anxiety. Based on data corresponding to 702 children (M age = 9.65, SD = 0.70; 51.9 % girls; 55 % Hispanic/Latino), findings showed some sex and ethnic variations in SCAS measured anxiety at the item and scale levels. Moreover, SCAS correspondence to the 5-item SCARED was found across ethnicity and sex. SCAS correspondence to teacher ratings was found for non-Hispanic White boys and non-Hispanic White girls, marginally in Hispanic/Latino boys, and poorly in Hispanic/Latino girls.

Development and implementation of an independence rating scale and evaluation process for nursing orientation of new graduates.

PubMed

Durkin, Gregory J

2010-01-01

A wide variety of evaluation formats are available for new graduate nurses, but most of them are single-point evaluation tools that do not provide a clear picture of progress for orientee or educator. This article describes the development of a Web-based evaluation tool that combines learning taxonomies with the Synergy model into a rating scale based on independent performance. The evaluation tool and process provides open 24/7 access to evaluation documentation for members of the orientation team, demystifying the process and clarifying expectations. The implementation of the tool has proven to be transformative in the perceptions of evaluation and performance expectations of new graduates. This tool has been successful at monitoring progress, altering education, and opening dialogue about performance for over 125 new graduate nurses since inception.

Validation of the Implementation Leadership Scale (ILS) with Supervisors' Self-Ratings.

PubMed

Torres, Elisa M; Ehrhart, Mark G; Beidas, Rinad S; Farahnak, Lauren R; Finn, Natalie K; Aarons, Gregory A

2018-01-01

Although often discussed, there is a lack of empirical research on the role of leadership in the management and delivery of health services. The implementation leadership scale (ILS) assesses the degree to which leaders are knowledgeable, proactive, perseverant, and supportive during evidence-based practice (EBP) implementation. The purpose of this study was to examine the psychometric properties of the ILS for leaders' self-ratings using a sample of mental health clinic supervisors (N = 119). Supervisors (i.e., leaders) completed surveys including self-ratings of their implementation leadership. Confirmatory factor analysis, reliability, and validity of the ILS were evaluated. The ILS factor structure was supported in the sample of supervisors. Results demonstrated internal consistency reliability and validity. Cronbach alpha's ranged from 0.92 to 0.96 for the ILS subscales and 0.95 for the ILS overall scale. The factor structure replication and reliability of the ILS in a sample of supervisors demonstrates its applicability with employees across organizational levels.

Kinetics of a Migration-Driven Aggregation-Fragmentation Process

NASA Astrophysics Data System (ADS)

Zhuang, You-Yi; Lin, Zhen-Quan; Ke, Jian-Hong

2003-08-01

We propose a reversible model of the migration-driven aggregation-fragmentation process with the symmetric migration rate kernels K(k;j)=K^'(k;j)=λ kj^v and the constant aggregation rates I1, I2 and fragmentation rates J1, J2. Based on the mean-field theory, we investigate the evolution behavior of the aggregate size distributions in several cases with different values of index υ. We find that the fragmentation reaction plays a more important role in the kinetic behaviors of the system than the aggregation and migration. When J1=0 and J2 =0, the aggregate size distributions ak(t) and bk(t) obey the conventional scaling law, while when J1>0 and J2>0, they obey the modified scaling law with an exponential scaling function. The total mass of either species remains conserved. The project supported by National Natural Science Foundation of China under Grant Nos. 10275048 and 10175008, and Natural Science Foundation of Zhejiang Province of China under Grant No. 102067

Sculling Compensation Algorithm for SINS Based on Two-Time Scale Perturbation Model of Inertial Measurements

PubMed Central

Wang, Lingling; Fu, Li

2018-01-01

In order to decrease the velocity sculling error under vibration environments, a new sculling error compensation algorithm for strapdown inertial navigation system (SINS) using angular rate and specific force measurements as inputs is proposed in this paper. First, the sculling error formula in incremental velocity update is analytically derived in terms of the angular rate and specific force. Next, two-time scale perturbation models of the angular rate and specific force are constructed. The new sculling correction term is derived and a gravitational search optimization method is used to determine the parameters in the two-time scale perturbation models. Finally, the performance of the proposed algorithm is evaluated in a stochastic real sculling environment, which is different from the conventional algorithms simulated in a pure sculling circumstance. A series of test results demonstrate that the new sculling compensation algorithm can achieve balanced real/pseudo sculling correction performance during velocity update with the advantage of less computation load compared with conventional algorithms. PMID:29346323

ADHD Diagnosis: As Simple As Administering a Questionnaire or a Complex Diagnostic Process?

PubMed

Parker, Ashton; Corkum, Penny

2016-06-01

The present study investigated the validity of using the Conners' Teacher and Parent Rating Scales (CTRS/CPRS) or semistructured diagnostic interviews (Parent Interview for Child Symptoms and Teacher Telephone Interview) to predict a best-practices clinical diagnosis of ADHD. A total of 279 children received a clinical diagnosis based on a best-practices comprehensive assessment (including diagnostic parent and teacher interviews, collection of historical information, rating scales, classroom observations, and a psychoeducational assessment) at a specialty ADHD Clinic in Truro, Nova Scotia, Canada. Sensitivity and specificity with clinical diagnosis were determined for the ratings scales and diagnostic interviews. Sensitivity and specificity values were high for the diagnostic interviews (91.8% and 70.7%, respectively). However, while sensitivity of the CTRS/CPRS was relatively high (83.5%), specificity was poor (35.7%). The low specificity of the CPRS/CTRS is not sufficient to be used alone to diagnose ADHD. (J. of Att. Dis. 2016; 20(6) 478-486). © The Author(s) 2013.

Dissolution of covalent adaptable network polymers in organic solvent

NASA Astrophysics Data System (ADS)

Yu, Kai; Yang, Hua; Dao, Binh H.; Shi, Qian; Yakacki, Christopher M.

2017-12-01

It was recently reported that thermosetting polymers can be fully dissolved in a proper organic solvent utilizing a bond-exchange reaction (BER), where small molecules diffuse into the polymer, break the long polymer chains into short segments, and eventually dissolve the network when sufficient solvent is provided. The solvent-assisted dissolution approach was applied to fully recycle thermosets and their fiber composites. This paper presents the first multi-scale modeling framework to predict the dissolution kinetics and mechanics of thermosets in organic solvent. The model connects the micro-scale network dynamics with macro-scale material properties: in the micro-scale, a model is developed based on the kinetics of BERs to describe the cleavage rate of polymer chains and evolution of chain segment length during the dissolution. The micro-scale model is then fed into a continuum-level model with considerations of the transportation of solvent molecules and chain segments in the system. The model shows good prediction on conversion rate of functional groups, degradation of network mechanical properties, and dissolution rate of thermosets during the dissolution. It identifies the underlying kinetic factors governing the dissolution process, and reveals the influence of different material and processing variables on the dissolution process, such as time, temperature, catalyst concentration, and chain length between cross-links.

Connections among soil, ground, and surface water chemistries characterize nitrogen loss from an agricultural landscape in the upper Missouri River Basin

NASA Astrophysics Data System (ADS)

Sigler, W. Adam; Ewing, Stephanie A.; Jones, Clain A.; Payn, Robert A.; Brookshire, E. N. Jack; Klassen, Jane K.; Jackson-Smith, Douglas; Weissmann, Gary S.

2018-01-01

Elevated nitrate in shallow aquifers is common in agricultural areas and remediation requires an understanding of nitrogen (N) leaching at a variety of spatial scales. Characterization of the drivers of nitrate leaching at the mesoscale level (102-103 km2) is needed to bridge from field-scale observations to the landscape-scale context, allowing informed water resource management decisions. Here we explore patterns in nitrate leaching rates across a depositional landform in the northern Great Plains within the Upper Missouri Basin, where the predominant land use is non-irrigated small grain production, and nitrate-N concentrations above 10 mg L-1 are common. The shallow Moccasin terrace (260 km2) aquifer is bounded in vertical extent by underlying shale and is isolated from mountain front stream recharge, such that aquifer recharge is dominated by infiltration of precipitation through agricultural soils. This configuration presents a simple landform-scale water balance that we leveraged to estimate leaching rates using groundwater nitrate concentrations and surface water discharge, and quantify uncertainty using a Monte Carlo approach based on spatial variation in observations of groundwater nitrate concentrations. A participatory research approach allowed local farmer knowledge of the landscape to be incorporated into the study design, improved selection of and access to sample sites, and enhanced prospects for addressing nitrate leaching through collaborative understanding of system hydrology. Mean landform-scale nitrate-N leaching rates were 11 and 18 kg ha-1 yr-1 during the 2012-2014 study for the two largest catchments draining the terrace. Over a standard three-year crop rotation, these leaching rates represent 19-31% of typical fertilizer N application rates; however, leaching losses are likely derived not only from fertilizer but also from soil organic N mineralization, and are apparently higher during the post-fallow phase of the crop rotation. Groundwater apparent age is relatively young (0-5 yr) based on tritium-helium analysis, but whole-aquifer turnover time calculations are an order of magnitude longer (20-23 yr), suggesting changes in groundwater may lag behind changes in land management by years to decades.

The role of soil weathering and hydrology in regulating chemical fluxes from catchments (Invited)

NASA Astrophysics Data System (ADS)

Maher, K.; Chamberlain, C. P.

2010-12-01

Catchment-scale chemical fluxes have been linked to a number of different parameters that describe the conditions at the Earth’s surface, including runoff, temperature, rock type, vegetation, and the rate of tectonic uplift. However, many of the relationships relating chemical denudation to surface processes and conditions, while based on established theoretical principles, are largely empirical and derived solely from modern observations. Thus, an enhanced mechanistic basis for linking global solute fluxes to both surface processes and climate may improve our confidence in extrapolating modern solute fluxes to past and future conditions. One approach is to link observations from detailed soil-based studies with catchment-scale properties. For example, a number of recent studies of chemical weathering at the soil-profile scale have reinforced the importance of hydrologic processes in controlling chemical weathering rates. An analysis of data from granitic soils shows that weathering rates decrease with increasing fluid residence times and decreasing flow rates—over moderate fluid residence times, from 5 days to 10 years, transport-controlled weathering explains the orders of magnitude variation in weathering rates to a better extent than soil age. However, the importance of transport-controlled weathering is difficult to discern at the catchment scale because of the range of flow rates and fluid residence times captured by a single discharge or solute flux measurement. To assess the importance of transport-controlled weathering on catchment scale chemical fluxes, we present a model that links the chemical flux to the extent of reaction between the soil waters and the solids, or the fluid residence time. Different approaches for describing the distribution of fluid residence times within a catchment are then compared with the observed Si fluxes for a limited number of catchments. This model predicts high solute fluxes in regions with high run-off, relief, and long flow paths suggesting that the particular hydrologic setting of a landscape will be the underlying control on the chemical fluxes. As such, we reinterpret the large chemical fluxes that are observed in active mountain belts, like the Himalaya, to be primarily controlled by the long reactive flow paths created by the steep terrain coupled with high amounts of precipitation.

Distributed intrusion detection system based on grid security model

NASA Astrophysics Data System (ADS)

Su, Jie; Liu, Yahui

2008-03-01

Grid computing has developed rapidly with the development of network technology and it can solve the problem of large-scale complex computing by sharing large-scale computing resource. In grid environment, we can realize a distributed and load balance intrusion detection system. This paper first discusses the security mechanism in grid computing and the function of PKI/CA in the grid security system, then gives the application of grid computing character in the distributed intrusion detection system (IDS) based on Artificial Immune System. Finally, it gives a distributed intrusion detection system based on grid security system that can reduce the processing delay and assure the detection rates.

Assessment of personality-related levels of functioning: a pilot study of clinical assessment of the DSM-5 level of personality functioning based on a semi-structured interview.

PubMed

Thylstrup, Birgitte; Simonsen, Sebastian; Nemery, Caroline; Simonsen, Erik; Noll, Jane Fjernestad; Myatt, Mikkel Wanting; Hesse, Morten

2016-08-25

The personality disorder categories in the Diagnostic and Statistical Manual of Mental Disorders IV have been extensively criticized, and there is a growing consensus that personality pathology should be represented dimensionally rather than categorically. The aim of this pilot study was to test the Clinical Assessment of the Level of Personality Functioning Scale, a semi-structured clinical interview, designed to assess the Level of Personality Functioning Scale of the DSM-5 (Section III) by applying strategies similar to what characterizes assessments in clinical practice. The inter-rater reliability of the assessment of the four domains and the total impairment in the Level of Personality Functioning Scale were measured in a patient sample that varied in terms of severity and type of pathology. Ratings were done independently by the interviewer and two experts who watched a videotaped Clinical Assessment of the Level of Personality Functioning Scale interview. Inter-rater reliability coefficients varied between domains and were not sufficient for clinical practice, but may support the use of the interview to assess the dimensions of personality functioning for research purposes. While designed to measure the Level of Personality Functioning Scale with a high degree of similarity to clinical practice, the Clinical Assessment of the Level of Personality Functioning Scale had weak reliabilities and a rating based on a single interview should not be considered a stand-alone assessment of areas of functioning for a given patient.

A real-time multi-scale 2D Gaussian filter based on FPGA

NASA Astrophysics Data System (ADS)

Luo, Haibo; Gai, Xingqin; Chang, Zheng; Hui, Bin

2014-11-01

Multi-scale 2-D Gaussian filter has been widely used in feature extraction (e.g. SIFT, edge etc.), image segmentation, image enhancement, image noise removing, multi-scale shape description etc. However, their computational complexity remains an issue for real-time image processing systems. Aimed at this problem, we propose a framework of multi-scale 2-D Gaussian filter based on FPGA in this paper. Firstly, a full-hardware architecture based on parallel pipeline was designed to achieve high throughput rate. Secondly, in order to save some multiplier, the 2-D convolution is separated into two 1-D convolutions. Thirdly, a dedicate first in first out memory named as CAFIFO (Column Addressing FIFO) was designed to avoid the error propagating induced by spark on clock. Finally, a shared memory framework was designed to reduce memory costs. As a demonstration, we realized a 3 scales 2-D Gaussian filter on a single ALTERA Cyclone III FPGA chip. Experimental results show that, the proposed framework can computing a Multi-scales 2-D Gaussian filtering within one pixel clock period, is further suitable for real-time image processing. Moreover, the main principle can be popularized to the other operators based on convolution, such as Gabor filter, Sobel operator and so on.

Reliability and validity of a tool to measure the severity of tongue thrust in children: the Tongue Thrust Rating Scale.

PubMed

Serel Arslan, S; Demir, N; Karaduman, A A

2017-02-01

This study aimed to develop a scale called Tongue Thrust Rating Scale (TTRS), which categorised tongue thrust in children in terms of its severity during swallowing, and to investigate its validity and reliability. The study describes the developmental phase of the TTRS and presented its content and criterion-based validity and interobserver and intra-observer reliability. For content validation, seven experts assessed the steps in the scale over two Delphi rounds. Two physical therapists evaluated videos of 50 children with cerebral palsy (mean age, 57·9 ± 16·8 months), using the TTRS to test criterion-based validity, interobserver and intra-observer reliability. The Karaduman Chewing Performance Scale (KCPS) and Drooling Severity and Frequency Scale (DSFS) were used for criterion-based validity. All the TTRS steps were deemed necessary. The content validity index was 0·857. A very strong positive correlation was found between two examinations by one physical therapist, which indicated intra-observer reliability (r = 0·938, P < 0·001). A very strong positive correlation was also found between the TTRS scores of two physical therapists, indicating interobserver reliability (r = 0·892, P < 0·001). There was also a strong positive correlation between the TTRS and KCPS (r = 0·724, P < 0·001) and a very strong positive correlation between the TTRS scores and DSFS (r = 0·822 and r = 0·755; P < 0·001). These results demonstrated the criterion-based validity of the TTRS. The TTRS is a valid, reliable and clinically easy-to-use functional instrument to document the severity of tongue thrust in children. © 2016 John Wiley & Sons Ltd.

Reef-scale modeling of coral calcification responses to ocean acidification and sea-level rise

NASA Astrophysics Data System (ADS)

Nakamura, Takashi; Nadaoka, Kazuo; Watanabe, Atsushi; Yamamoto, Takahiro; Miyajima, Toshihiro; Blanco, Ariel C.

2018-03-01

To predict coral responses to future environmental changes at the reef scale, the coral polyp model (Nakamura et al. in Coral Reefs 32:779-794, 2013), which reconstructs coral responses to ocean acidification, flow conditions and other factors, was incorporated into a reef-scale three-dimensional hydrodynamic-biogeochemical model. This coupled reef-scale model was compared to observations from the Shiraho fringing reef, Ishigaki Island, Japan, where the model accurately reconstructed spatiotemporal variation in reef hydrodynamic and geochemical parameters. The simulated coral calcification rate exhibited high spatial variation, with lower calcification rates in the nearshore and stagnant water areas due to isolation of the inner reef at low tide, and higher rates on the offshore side of the inner reef flat. When water is stagnant, bottom shear stress is low at night and thus oxygen diffusion rate from ambient water to the inside of the coral polyp limits respiration rate. Thus, calcification decreases because of the link between respiration and calcification. A scenario analysis was conducted using the reef-scale model with several pCO2 and sea-level conditions based on IPCC (Climate change 2013: the physical science basis. Contribution of working group I to the fifth assessment report of the intergovernmental panel on climate change, Cambridge University Press, Cambridge, 2013) scenarios. The simulation indicated that the coral calcification rate decreases with increasing pCO2. On the other hand, sea-level rise increases the calcification rate, particularly in the nearshore and the areas where water is stagnant at low tide under present conditions, as mass exchange, especially oxygen exchange at night, is enhanced between the corals and their ambient seawater due to the reduced stagnant period. When both pCO2 increase and sea-level rise occur concurrently, the calcification rate generally decreases due to the effects of ocean acidification. However, the calcification rate in some inner-reef areas will increase because the positive effects of sea-level rise offset the negative effects of ocean acidification, and total calcification rate will be positive only under the best-case scenario (RCP 2.6).

The initial stage of uranium oxidation: mechanism of UO(2) scale formation in the presence of a native lateral stress field.

PubMed

Chernia, Z; Ben-Eliyahu, Y; Kimmel, G; Braun, G; Sariel, J

2006-11-23

In this work, an oxidation model for alpha-uranium is presented. It describes the internally lateral stress field built in the oxide scale during the reaction. The thickness of the elastic, stress-preserving oxide (UO(2+x)) scale is less than 0.5 microm. A lateral, 6.5 GPa stress field has been calculated from strains derived from line shifts (delta(2theta)) as measured by the X-ray diffraction of UO(2). It is shown that in the elastic growth domain, (110) is the main UO(2) growth plane for gas-solid oxidation. The diffusion-limited oxidation mechanism discussed here is based on the known "2:2:2" cluster theory which describes the mechanism of fluorite-based hyperstoichiometric oxides. In this study, it is adapted to describe oxygen-anion hopping. Anion hopping toward the oxide-metal interface proceeds at high rates in the [110] direction, hence making this pipeline route the principal growth direction in UO(2) formation. It is further argued that growth in the pure elastic domain of the oxide scale should be attributed entirely to anion hopping in 110. Anions, diffusing isotropically via grain boundaries and cracks, are shown to have a significant impact on the overall oxidation rate in relatively thick (>0.35 microm) oxide scales if followed by an avalanche break off in the postelastic regime. Stress affects oxidation in the elastic domain by controlling the hopping rate directly. In the postelastic regime, stress weakens hopping, indirectly, by enhancing isotropic diffusion. Surface roughness presents an additional hindering factor for the anion hopping. In comparison to anisotropic hopping, diffusion of isotropic hopping has a lower activation energy barrier. Therefore, a relatively stronger impact at lower temperatures due to isotropic diffusion is displayed.

Validation of the Persian version of the Schizophrenia Cognition Rating Scale (SCoRS) in patients with schizophrenia.

PubMed

Mazhari, Shahrzad; Ghafaree-Nejad, Ali R; Soleymani-Zade, Somayeh; Keefe, Richard S E

2017-06-01

The Schizophrenia Cognition Rating Scale (SCoRS) is an interview-based assessment of cognition that involves interviews with patients and informants. The SCoRS has shown good reliability, validity, and sensitivity to cognitive impairment in schizophrenia, with the advantage of brief administration and scoring time. The present study aimed to test the concurrent validity of the Persian version of the SCoRS. A group of 35 patients with schizophrenia and a group of 35 healthy controls received the Persian-SCoRS in the first session, and a standardized performance-based cognitive battery, the Brief Assessment of Cognition in Schizophrenia (BACS), in the second session.Our results indicated that the Persian version of the SCoRS was sensitive to cognitive impairment in the patients. The Persian SCoRS global rating was significantly associated with the composite score generated from the Persian version of the BACS and predicted functional outcomes as measured by Global Assessment of Functioning (GAF) and World Health Organization Quality of Life (WHO QOL). A Persian version of the SCoRS, an interview based measure of cognition that included informants, is related to cognitive performance and global functioning. Copyright © 2017 Elsevier B.V. All rights reserved.

All-fibre photonic signal generator for attosecond timing and ultralow-noise microwave

PubMed Central

Jung, Kwangyun; Kim, Jungwon

2015-01-01

High-impact frequency comb applications that are critically dependent on precise pulse timing (i.e., repetition rate) have recently emerged and include the synchronization of X-ray free-electron lasers, photonic analogue-to-digital conversion and photonic radar systems. These applications have used attosecond-level timing jitter of free-running mode-locked lasers on a fast time scale within ~100 μs. Maintaining attosecond-level absolute jitter over a significantly longer time scale can dramatically improve many high-precision comb applications. To date, ultrahigh quality-factor (Q) optical resonators have been used to achieve the highest-level repetition-rate stabilization of mode-locked lasers. However, ultrahigh-Q optical-resonator-based methods are often fragile, alignment sensitive and complex, which limits their widespread use. Here we demonstrate a fibre-delay line-based repetition-rate stabilization method that enables the all-fibre photonic generation of optical pulse trains with 980-as (20-fs) absolute r.m.s. timing jitter accumulated over 0.01 s (1 s). This simple approach is based on standard off-the-shelf fibre components and can therefore be readily used in various comb applications that require ultra-stable microwave frequency and attosecond optical timing. PMID:26531777

How systematic age underestimation can impede understanding of fish population dynamics: Lessons learned from a Lake Superior cisco stock

USGS Publications Warehouse

Yule, D.L.; Stockwell, J.D.; Black, J.A.; Cullis, K.I.; Cholwek, G.A.; Myers, J.T.

2008-01-01

Systematic underestimation of fish age can impede understanding of recruitment variability and adaptive strategies (like longevity) and can bias estimates of survivorship. We suspected that previous estimates of annual survival (S; range = 0.20-0.44) for Lake Superior ciscoes Coregonus artedi developed from scale ages were biased low. To test this hypothesis, we estimated the total instantaneous mortality rate of adult ciscoes from the Thunder Bay, Ontario, stock by use of cohort-based catch curves developed from commercial gill-net catches and otolith-aged fish. Mean S based on otolith ages was greater for adult females (0.80) than for adult males (0.75), but these differences were not significant. Applying the results of a study of agreement between scale and otolith ages, we modeled a scale age for each otolith-aged fish to reconstruct catch curves. Using modeled scale ages, estimates of S (0.42 for females, 0.36 for males) were comparable with those reported in past studies. We conducted a November 2005 acoustic and midwater trawl survey to estimate the abundance of ciscoes when the fish were being harvested for roe. Estimated exploitation rates were 0.085 for females and 0.025 for males, and the instantaneous rates of fishing mortality were 0.089 for females and 0.025 for males. The instantaneous rates of natural mortality were 0.131 and 0.265 for females and males, respectively. Using otolith ages, we found that strong year-classes at large during November 2005 were caught in high numbers as age-1 fish in previous annual bottom trawl surveys, whereas weak or absent year-classes were not. For decades, large-scale fisheries on the Great Lakes were allowed to operate because ciscoes were assumed to be short lived and to have regular recruitment. We postulate that the collapse of these fisheries was linked in part to a misunderstanding of cisco biology driven by scale-ageing error. ?? Copyright by the American Fisheries Society 2008.

Revisiting the generalized scaling law for adhesion: role of compliance and extension to progressive failure.

PubMed

Mojdehi, Ahmad R; Holmes, Douglas P; Dillard, David A

2017-10-25

A generalized scaling law, based on the classical fracture mechanics approach, is developed to predict the bond strength of adhesive systems. The proposed scaling relationship depends on the rate of change of debond area with compliance, rather than the ratio of area to compliance. This distinction can have a profound impact on the expected bond strength of systems, particularly when the failure mechanism changes or the compliance of the load train increases. Based on the classical fracture mechanics approach for rate-independent materials, the load train compliance should not affect the force capacity of the adhesive system, whereas when the area to compliance ratio is used as the scaling parameter, it directly influences the bond strength, making it necessary to distinguish compliance contributions. To verify the scaling relationship, single lap shear tests were performed for a given pressure sensitive adhesive (PSA) tape specimens with different bond areas, number of backing layers, and load train compliance. The shear lag model was used to derive closed-form relationships for the system compliance and its derivative with respect to the debond area. Digital image correlation (DIC) is implemented to verify the non-uniform shear stress distribution obtained from the shear lag model in a lap shear geometry. The results obtained from this approach could lead to a better understanding of the relationship between bond strength and the geometry and mechanical properties of adhesive systems.

Validity of Level of Supervision Scales for Assessing Pediatric Fellows on the Common Pediatric Subspecialty Entrustable Professional Activities.

PubMed

Mink, Richard B; Schwartz, Alan; Herman, Bruce E; Turner, David A; Curran, Megan L; Myers, Angela; Hsu, Deborah C; Kesselheim, Jennifer C; Carraccio, Carol L

2018-02-01

Entrustable professional activities (EPAs) represent the routine and essential activities that physicians perform in practice. Although some level of supervision scales have been proposed, they have not been validated. In this study, the investigators created level of supervision scales for EPAs common to the pediatric subspecialties and then examined their validity in a study conducted by the Subspecialty Pediatrics Investigator Network (SPIN). SPIN Steering Committee members used a modified Delphi process to develop unique scales for six of the seven common EPAs. The investigators sought validity evidence in a multisubspecialty study in which pediatric fellowship program directors and Clinical Competency Committees used the scales to evaluate fellows in fall 2014 and spring 2015. Separate scales for the six EPAs, each with five levels of progressive entrustment, were created. In both fall and spring, more than 300 fellows in each year of training from over 200 programs were assessed. In both periods and for each EPA, there was a progressive increase in entrustment levels, with second-year fellows rated higher than first-year fellows (P < .001) and third-year fellows rated higher than second-year fellows (P < .001). For each EPA, spring ratings were higher (P < .001) than those in the fall. Interrater reliability was high (Janson and Olsson's iota = 0.73). The supervision scales developed for these six common pediatric subspecialty EPAs demonstrated strong validity evidence for use in EPA-based assessment of pediatric fellows. They may also inform the development of scales in other specialties.

A multi-scale GIS and hydrodynamic modelling approach to fish passage assessment: Clarence and Shoalhaven Rivers, NSW Australia

NASA Astrophysics Data System (ADS)

Bonetti, Rita M.; Reinfelds, Ivars V.; Butler, Gavin L.; Walsh, Chris T.; Broderick, Tony J.; Chisholm, Laurie A.

2016-05-01

Natural barriers such as waterfalls, cascades, rapids and riffles limit the dispersal and in-stream range of migratory fish, yet little is known of the interplay between these gradient dependent landforms, their hydraulic characteristics and flow rates that facilitate fish passage. The resurgence of dam construction in numerous river basins world-wide provides impetus to the development of robust techniques for assessment of the effects of downstream flow regime changes on natural fish passage barriers and associated consequences as to the length of rivers available to migratory species. This paper outlines a multi-scale technique for quantifying the relative magnitude of natural fish passage barriers in river systems and flow rates that facilitate passage by fish. First, a GIS-based approach is used to quantify channel gradients for the length of river or reach under investigation from a high resolution DEM, setting the magnitude of identified passage barriers in a longer context (tens to hundreds of km). Second, LiDAR, topographic and bathymetric survey-based hydrodynamic modelling is used to assess flow rates that can be regarded as facilitating passage across specific barriers identified by the river to reach scale gradient analysis. Examples of multi-scale approaches to fish passage assessment for flood-flow and low-flow passage issues are provided from the Clarence and Shoalhaven Rivers, NSW, Australia. In these river systems, passive acoustic telemetry data on actual movements and migrations by Australian bass (Macquaria novemaculeata) provide a means of validating modelled assessments of flow rates associated with successful fish passage across natural barriers. Analysis of actual fish movements across passage barriers in these river systems indicates that two dimensional hydraulic modelling can usefully quantify flow rates associated with the facilitation of fish passage across natural barriers by a majority of individual fishes for use in management decisions regarding environmental or instream flows.

SU-E-T-472: Improvement of IMRT QA Passing Rate by Correcting Angular Dependence of MatriXX

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Q; Watkins, W; Kim, T

2015-06-15

Purpose: Multi-channel planar detector arrays utilized for IMRT-QA, such as the MatriXX, exhibit an incident-beam angular dependent response which can Result in false-positive gamma-based QA results, especially for helical tomotherapy plans which encompass the full range of beam angles. Although MatriXX can use with gantry angle sensor to provide automatically angular correction, this sensor does not work with tomotherapy. The purpose of the study is to reduce IMRT-QA false-positives by correcting for the MatriXX angular dependence. Methods: MatriXX angular dependence was characterized by comparing multiple fixed-angle irradiation measurements with corresponding TPS computed doses. For 81 Tomo-helical IMRT-QA measurements, two differentmore » correction schemes were tested: (1) A Monte-Carlo dose engine was used to compute MatriXX signal based on the angular-response curve. The computed signal was then compared with measurement. (2) Uncorrected computed signal was compared with measurements uniformly scaled to account for the average angular dependence. Three scaling factor (+2%, +2.5%, +3%) were tested. Results: The MatriXX response is 8% less than predicted for a PA beam even when the couch is fully accounted for. Without angular correction, only 67% of the cases pass the >90% points γ<1 (3%, 3mm). After full angular correction, 96% of the cases pass the criteria. Of three scaling factors, +2% gave the highest passing rate (89%), which is still less than the full angular correction method. With a stricter γ(2%,3mm) criteria, the full angular correction method was still able to achieve the 90% passing rate while the scaling method only gives 53% passing rate. Conclusion: Correction for the MatriXX angular dependence reduced the false-positives rate of our IMRT-QA process. It is necessary to correct for the angular dependence to achieve the IMRT passing criteria specified in TG129.« less

Large-scale preparation of clove essential oil and eugenol-loaded liposomes using a membrane contactor and a pilot plant.

PubMed

Sebaaly, Carine; Greige-Gerges, Hélène; Agusti, Géraldine; Fessi, Hatem; Charcosset, Catherine

2016-01-01

Based on our previous study where optimal conditions were defined to encapsulate clove essential oil (CEO) into liposomes at laboratory scale, we scaled-up the preparation of CEO and eugenol (Eug)-loaded liposomes using a membrane contactor (600 mL) and a pilot plant (3 L) based on the principle of ethanol injection method, both equipped with a Shirasu Porous Glass membrane for injection of the organic phase into the aqueous phase. Homogenous, stable, nanometric-sized and multilamellar liposomes with high phospholipid, Eug loading rates and encapsulation efficiency of CEO components were obtained. Saturation of phospholipids and drug concentration in the organic phase may control the liposome stability. Liposomes loaded with other hydrophobic volatile compounds could be prepared at large scale using the ethanol injection method and a membrane for injection.

Scaling of ratings: Concepts and methods

Treesearch

Thomas C. Brown; Terry C. Daniel

1990-01-01

Rating scales provide an efficient and widely used means of recording judgments. This paper reviews scaling issues within the context of a psychometric model of the rating process, describes several methods of scaling rating data, and compares the methods in terms of the assumptions they require about the rating process and the information they provide about the...

Allometric relationship of postmolt net ion uptake, ventilation, and circulation in the freshwater crayfish Procambarus clarkii: intraspecific scaling.

PubMed

Zanotto, F P; Wheatly, M G; Reiber, C L; Gannon, A T; Jalles-Filho, E

2004-01-01

There are few intraspecific studies relating physiological parameters to body mass. This study relates scaling of ionic regulation and respiratory parameters with body mass in crayfish (Procambarus clarkii). These animals were chosen because of their direct development, spanning four orders of magnitude in body mass. Usually, these animals are hyperregulators and must maintain hemolymph electrolyte levels above those in the ambient freshwater. This is especially important in the postmolt, when ion imbalance can occur. Maintaining hemolymph ion levels above ambient involves active processes that are independently related to metabolic rate, ventilation, and circulation. Therefore, this study investigates relationships among size and ionic regulation, heart rate, and ventilation in crayfish, spanning a size range of 0.003-24 g. Postmolt net ion uptake of Ca, titratable base, Na, Cl, and NH4 increase with body mass (positive allometry) with slopes of 0.92, 0.79, 0.90, 0.84, and 0.87, respectively. Between 72% and 97% of variation in ionic regulation was related to body mass. The slopes differed from each other for Ca and titratable base but not for Na, Cl, and NH4. For heart rate and ventilation rate, different relationships were derived for animals smaller and larger than 0.01 g (between first and third instar). Animals larger than 0.01 g show a negative allometric relationship between heart rate and body size ([body mass](0.15)), while smaller animals show positive allometry with body size, but only 29% of variation in heart rate is explained by body size alone. For ventilation rates, the negative allometry with body size for animals larger than 0.01 g is present, but less than 15% of variation in ventilation rate is explained by size, while for smaller animals the size dependency disappears. Based on these results, predictions of physiological parameters such as ionic regulation based on body size are useful in crayfish, but estimates of respiratory parameters and body size should be used with caution.

Credit PSR. This view of the interior of the weighing ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Credit PSR. This view of the interior of the weighing facility looks through the open double doors on the south side. A Toledo scale, rated at 3,000 pounds (1,363 Kg), is installed in the center of the floor; the smaller scale in the corner is rated for 200 pounds (91 Kg). The wall-mounted recording device records quantities weighed and serves as a record displaying that substances were in fact weighed. Note the explosion-proof fluorescent lighting above, and the 0.5 ton hoist - Jet Propulsion Laboratory Edwards Facility, Oxidizer Weigh & Storage Building, Edwards Air Force Base, Boron, Kern County, CA

Precipitation Estimation from Remotely Sensed Information using Artificial Neural Network-Cloud Classification System

NASA Astrophysics Data System (ADS)

Hong, Yang

Precipitation estimation from satellite information (VISIBLE , IR, or microwave) is becoming increasingly imperative because of its high spatial/temporal resolution and board coverage unparalleled by ground-based data. After decades' efforts of rainfall estimation using IR imagery as basis, it has been explored and concluded that the limitations/uncertainty of the existing techniques are: (1) pixel-based local-scale feature extraction; (2) IR temperature threshold to define rain/no-rain clouds; (3) indirect relationship between rain rate and cloud-top temperature; (4) lumped techniques to model high variability of cloud-precipitation processes; (5) coarse scales of rainfall products. As continuing studies, a new version of Precipitation Estimation from Remotely Sensed Information using Artificial Neural Network (PERSIANN), called Cloud Classification System (CCS), has been developed to cope with these limitations in this dissertation. CCS includes three consecutive components: (1) a hybrid segmentation algorithm, namely Hierarchically Topographical Thresholding and Stepwise Seeded Region Growing (HTH-SSRG), to segment satellite IR images into separated cloud patches; (2) a 3D feature extraction procedure to retrieve both pixel-based local-scale and patch-based large-scale features of cloud patch at various heights; (3) an ANN model, Self-Organizing Nonlinear Output (SONO) network, to classify cloud patches into similarity-based clusters, using Self-Organizing Feature Map (SOFM), and then calibrate hundreds of multi-parameter nonlinear functions to identify the relationship between every cloud types and their underneath precipitation characteristics using Probability Matching Method and Multi-Start Downhill Simplex optimization techniques. The model was calibrated over the Southwest of United States (100°--130°W and 25°--45°N) first and then adaptively adjusted to the study region of North America Monsoon Experiment (65°--135°W and 10°--50°N) using observations from Geostationary Operational Environmental Satellite (GOES) IR imagery, Next Generation Radar (NEXRAD) rainfall network, and Tropical Rainfall Measurement Mission (TRMM) microwave rain rate estimates. CCS functions as a distributed model that first identifies cloud patches and then dispatches different but the best matching cloud-precipitation function for each cloud patch to estimate instantaneous rain rate at high spatial resolution (4km) and full temporal resolution of GOES IR images (every 30-minute). Evaluated over a range of spatial and temporal scales, the performance of CCS compared favorably with GOES Precipitation Index (GPI), Universal Adjusted GPI (UAGPI), PERSIANN, and Auto-Estimator (AE) algorithms, consistently. Particularly, the large number of nonlinear functions and optimum IR-rain rate thresholds of CCS model are highly variable, reflecting the complexity of dominant cloud-precipitation processes from cloud patch to cloud patch over various regions. As a result, CCS can more successfully capture variability in rain rate at small scales than existing algorithms and potentially provides rainfall product from GOES IR-NEXARD-TRMM TMI (SSM/I) at 0.12° x 0.12° and 3-hour resolution with relative low standard error (˜=3.0mm/hr) and high correlation coefficient (˜=0.65).

On the context-dependent scaling of consumer feeding rates.

PubMed

Barrios-O'Neill, Daniel; Kelly, Ruth; Dick, Jaimie T A; Ricciardi, Anthony; MacIsaac, Hugh J; Emmerson, Mark C

2016-06-01

The stability of consumer-resource systems can depend on the form of feeding interactions (i.e. functional responses). Size-based models predict interactions - and thus stability - based on consumer-resource size ratios. However, little is known about how interaction contexts (e.g. simple or complex habitats) might alter scaling relationships. Addressing this, we experimentally measured interactions between a large size range of aquatic predators (4-6400 mg over 1347 feeding trials) and an invasive prey that transitions among habitats: from the water column (3D interactions) to simple and complex benthic substrates (2D interactions). Simple and complex substrates mediated successive reductions in capture rates - particularly around the unimodal optimum - and promoted prey population stability in model simulations. Many real consumer-resource systems transition between 2D and 3D interactions, and along complexity gradients. Thus, Context-Dependent Scaling (CDS) of feeding interactions could represent an unrecognised aspect of food webs, and quantifying the extent of CDS might enhance predictive ecology. © The Authors. Ecology Letters published by CNRS and John Wiley & Sons Ltd.

Development of a scale of executive functioning for the RBANS.

PubMed

Spencer, Robert J; Kitchen Andren, Katherine A; Tolle, Kathryn A

2018-01-01

The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) is a cognitive battery that contains scales of several cognitive abilities, but no scale in the instrument is exclusively dedicated to executive functioning. Although the subtests allow for observation of executive-type errors, each error is of fairly low base rate, and healthy and clinical normative data are lacking on the frequency of these types of errors, making their significance difficult to interpret in isolation. The aim of this project was to create an RBANS executive errors scale (RBANS EE) with items comprised of qualitatively dysexecutive errors committed throughout the test. Participants included Veterans referred for outpatient neuropsychological testing. Items were initially selected based on theoretical literature and were retained based on item-total correlations. The RBANS EE (a percentage calculated by dividing the number of dysexecutive errors by the total number of responses) was moderately related to each of seven established measures of executive functioning and was strongly predictive of dichotomous classification of executive impairment. Thus, the scale had solid concurrent validity, justifying its use as a supplementary scale. The RBANS EE requires no additional administration time and can provide a quantified measure of otherwise unmeasured aspects of executive functioning.

A dual theory of price and value in a meso-scale economic model with stochastic profit rate

NASA Astrophysics Data System (ADS)

Greenblatt, R. E.

2014-12-01

The problem of commodity price determination in a market-based, capitalist economy has a long and contentious history. Neoclassical microeconomic theories are based typically on marginal utility assumptions, while classical macroeconomic theories tend to be value-based. In the current work, I study a simplified meso-scale model of a commodity capitalist economy. The production/exchange model is represented by a network whose nodes are firms, workers, capitalists, and markets, and whose directed edges represent physical or monetary flows. A pair of multivariate linear equations with stochastic input parameters represent physical (supply/demand) and monetary (income/expense) balance. The input parameters yield a non-degenerate profit rate distribution across firms. Labor time and price are found to be eigenvector solutions to the respective balance equations. A simple relation is derived relating the expected value of commodity price to commodity labor content. Results of Monte Carlo simulations are consistent with the stochastic price/labor content relation.

Diffusion-Based Density-Equalizing Maps: an Interdisciplinary Approach to Visualizing Homicide Rates and Other Georeferenced Statistical Data

NASA Astrophysics Data System (ADS)

Mazzitello, Karina I.; Candia, Julián

2012-12-01

In every country, public and private agencies allocate extensive funding to collect large-scale statistical data, which in turn are studied and analyzed in order to determine local, regional, national, and international policies regarding all aspects relevant to the welfare of society. One important aspect of that process is the visualization of statistical data with embedded geographical information, which most often relies on archaic methods such as maps colored according to graded scales. In this work, we apply nonstandard visualization techniques based on physical principles. We illustrate the method with recent statistics on homicide rates in Brazil and their correlation to other publicly available data. This physics-based approach provides a novel tool that can be used by interdisciplinary teams investigating statistics and model projections in a variety of fields such as economics and gross domestic product research, public health and epidemiology, sociodemographics, political science, business and marketing, and many others.

A Model-Free Diagnostic for Single-Peakedness of Item Responses Using Ordered Conditional Means.

PubMed

Polak, Marike; de Rooij, Mark; Heiser, Willem J

2012-09-01

In this article we propose a model-free diagnostic for single-peakedness (unimodality) of item responses. Presuming a unidimensional unfolding scale and a given item ordering, we approximate item response functions of all items based on ordered conditional means (OCM). The proposed OCM methodology is based on Thurstone & Chave's (1929) criterion of irrelevance, which is a graphical, exploratory method for evaluating the "relevance" of dichotomous attitude items. We generalized this criterion to graded response items and quantified the relevance by fitting a unimodal smoother. The resulting goodness-of-fit was used to determine item fit and aggregated scale fit. Based on a simulation procedure, cutoff values were proposed for the measures of item fit. These cutoff values showed high power rates and acceptable Type I error rates. We present 2 applications of the OCM method. First, we apply the OCM method to personality data from the Developmental Profile; second, we analyze attitude data collected by Roberts and Laughlin (1996) concerning opinions of capital punishment.

Corrosion Performance of Fe-Based Alloys in Simulated Oxy-Fuel Environment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zeng, Zuotao; Natesan, Ken; Cai, Zhonghou

The long-term corrosion of Fe-based alloys in simulated oxy-fuel environment at 1023 K (750 A degrees C) was studied. Detailed results are presented on weight change, scale thickness, internal penetration, microstructural characteristics of the corrosion products, and the cracking of scales for the alloys after exposure at 1023 K (750 A degrees C) for up to 3600 hours. An incubation period during which the corrosion rate was low was observed for the alloys. After the incubation period, the corrosion accelerated, and the corrosion process followed linear kinetics. Effects of alloy, CaO-containing ash, and gas composition on the corrosion rate weremore » also studied. In addition, synchrotron nanobeam X-ray analysis was employed to determine the phase and chemical composition of the oxide layers on the alloy surface. Results from these studies are being used to address the long-term corrosion performance of Fe-based alloys in various coal-ash combustion environments and to develop methods to mitigate high-temperature ash corrosion.« less

Do Health Care Providers Use Online Patient Ratings to Improve the Quality of Care? Results From an Online-Based Cross-Sectional Study.

PubMed

Emmert, Martin; Meszmer, Nina; Sander, Uwe

2016-09-19

Physician-rating websites have become a popular tool to create more transparency about the quality of health care providers. So far, it remains unknown whether online-based rating websites have the potential to contribute to a better standard of care. Our goal was to examine which health care providers use online rating websites and for what purposes, and whether health care providers use online patient ratings to improve patient care. We conducted an online-based cross-sectional study by surveying 2360 physicians and other health care providers (September 2015). In addition to descriptive statistics, we performed multilevel logistic regression models to ascertain the effects of providers' demographics as well as report card-related variables on the likelihood that providers implement measures to improve patient care. Overall, more than half of the responding providers surveyed (54.66%, 1290/2360) used online ratings to derive measures to improve patient care (implemented measures: mean 3.06, SD 2.29). Ophthalmologists (68%, 40/59) and gynecologists (65.4%, 123/188) were most likely to implement any measures. The most widely implemented quality measures were related to communication with patients (28.77%, 679/2360), the appointment scheduling process (23.60%, 557/2360), and office workflow (21.23%, 501/2360). Scaled-survey results had a greater impact on deriving measures than narrative comments. Multilevel logistic regression models revealed medical specialty, the frequency of report card use, and the appraisal of the trustworthiness of scaled-survey ratings to be significantly associated predictors for implementing measures to improve patient care because of online ratings. Our results suggest that online ratings displayed on physician-rating websites have an impact on patient care. Despite the limitations of our study and unintended consequences of physician-rating websites, they still may have the potential to improve patient care.

Virus removal retention challenge tests performed at lab scale and pilot scale during operation of membrane units.

PubMed

Humbert, H; Machinal, C; Labaye, Ivan; Schrotter, J C

2011-01-01

The determination of the virus retention capabilities of UF units during operation is essential for the operators of drinking water treatment facilities in order to guarantee an efficient and stable removal of viruses through time. In previous studies, an effective method (MS2-phage challenge tests) was developed by the Water Research Center of Veolia Environnement for the measurement of the virus retention rates (Log Removal Rate, LRV) of commercially available hollow fiber membranes at lab scale. In the present work, the protocol for monitoring membrane performance was transferred from lab scale to pilot scale. Membrane performances were evaluated during pilot trial and compared to the results obtained at lab scale with fibers taken from the pilot plant modules. PFU culture method was compared to RT-PCR method for the calculation of LRV in both cases. Preliminary tests at lab scale showed that both methods can be used interchangeably. For tests conducted on virgin membrane, a good consistency was observed between lab and pilot scale results with the two analytical methods used. This work intends to show that a reliable determination of the membranes performances based on RT-PCR analytical method can be achieved during the operation of the UF units.

Evaluation of TRMM Ground-Validation Radar-Rain Errors Using Rain Gauge Measurements

NASA Technical Reports Server (NTRS)

Wang, Jianxin; Wolff, David B.

2009-01-01

Ground-validation (GV) radar-rain products are often utilized for validation of the Tropical Rainfall Measuring Mission (TRMM) spaced-based rain estimates, and hence, quantitative evaluation of the GV radar-rain product error characteristics is vital. This study uses quality-controlled gauge data to compare with TRMM GV radar rain rates in an effort to provide such error characteristics. The results show that significant differences of concurrent radar-gauge rain rates exist at various time scales ranging from 5 min to 1 day, despite lower overall long-term bias. However, the differences between the radar area-averaged rain rates and gauge point rain rates cannot be explained as due to radar error only. The error variance separation method is adapted to partition the variance of radar-gauge differences into the gauge area-point error variance and radar rain estimation error variance. The results provide relatively reliable quantitative uncertainty evaluation of TRMM GV radar rain estimates at various times scales, and are helpful to better understand the differences between measured radar and gauge rain rates. It is envisaged that this study will contribute to better utilization of GV radar rain products to validate versatile spaced-based rain estimates from TRMM, as well as the proposed Global Precipitation Measurement, and other satellites.

Physically based multiscale-viscoplastic model for metals and steel alloys: Theory and computation

NASA Astrophysics Data System (ADS)

Abed, Farid H.

The main requirement of large deformation problems such as high-speed machining, impact, and various primarily metal forming, is to develop constitutive relations which are widely applicable and capable of accounting for complex paths of deformation. Achieving such desirable goals for material like metals and steel alloys involves a comprehensive study of their microstructures and experimental observations under different loading conditions. In general, metal structures display a strong rate- and temperature-dependence when deformed non-uniformly into the inelastic range. This effect has important implications for an increasing number of applications in structural and engineering mechanics. The mechanical behavior of these applications cannot be characterized by classical (rate-independent) continuum theories because they incorporate no 'material length scales'. It is therefore necessary to develop a rate-dependent (viscoplasticity) continuum theory bridging the gap between the classical continuum theories and the microstructure simulations. Physically based vicoplasticity models for different types of metals (body centered cubic, face centered cubic and hexagonal close-packed) and steel alloys are derived in this work for this purpose. We adopt a multi-scale, hierarchical thermodynamic consistent framework to construct the material constitutive relations for the rate-dependent behavior. The concept of thermal activation energy, dislocations interactions mechanisms and the role of dislocations dynamics in crystals are used in the derivation process taking into consideration the contribution of the plastic strain evolution of dislocation density to the flow stress of polycrystalline metals. Material length scales are implicitly introduced into the governing equations through material rate-dependency (viscosity). The proposed framework is implemented into the commercially well-known finite element software ABAQUS. The finite element simulations of material instability problems converge to meaningful results upon further refinement of the finite element mesh due to the successful incorporation of the material length scale in the model formulations. It is shown that the model predicted results compare very well with different experimental data over a wide range of temperatures (77K°-1000K°) and strain rates (10-3-10 4s-1). It is also concluded from this dissertation that the width of localization zone (shear band) exhibits tremendous changes with different initial temperatures (i.e., different initial viscosities and accordingly different length scales).

The scaling of contact rates with population density for the infectious disease models.

PubMed

Hu, Hao; Nigmatulina, Karima; Eckhoff, Philip

2013-08-01

Contact rates and patterns among individuals in a geographic area drive transmission of directly-transmitted pathogens, making it essential to understand and estimate contacts for simulation of disease dynamics. Under the uniform mixing assumption, one of two mechanisms is typically used to describe the relation between contact rate and population density: density-dependent or frequency-dependent. Based on existing evidence of population threshold and human mobility patterns, we formulated a spatial contact model to describe the appropriate form of transmission with initial growth at low density and saturation at higher density. We show that the two mechanisms are extreme cases that do not capture real population movement across all scales. Empirical data of human and wildlife diseases indicate that a nonlinear function may work better when looking at the full spectrum of densities. This estimation can be applied to large areas with population mixing in general activities. For crowds with unusually large densities (e.g., transportation terminals, stadiums, or mass gatherings), the lack of organized social contact structure deviates the physical contacts towards a special case of the spatial contact model - the dynamics of kinetic gas molecule collision. In this case, an ideal gas model with van der Waals correction fits well; existing movement observation data and the contact rate between individuals is estimated using kinetic theory. A complete picture of contact rate scaling with population density may help clarify the definition of transmission rates in heterogeneous, large-scale spatial systems. Copyright © 2013 The Authors. Published by Elsevier Inc. All rights reserved.

Harbour porpoise distribution can vary at small spatiotemporal scales in energetic habitats

NASA Astrophysics Data System (ADS)

Benjamins, Steven; van Geel, Nienke; Hastie, Gordon; Elliott, Jim; Wilson, Ben

2017-07-01

Marine habitat heterogeneity underpins species distribution and can be generated through interactions between physical and biological drivers at multiple spatiotemporal scales. Passive acoustic monitoring (PAM) is used worldwide to study potential impacts of marine industrial activities on cetaceans, but understanding of animals' site use at small spatiotemporal scales (<1 km, <1 day) remains limited. Small-scale variability in vocalising harbour porpoise (Phocoena phocoena) distribution within two Scottish marine renewable energy development (MRED) sites was investigated by deploying dense arrays of C-POD passive acoustic detectors at a wave energy test site (the European Marine Energy Centre [Billia Croo, Orkney]) and by a minor tidal-stream site (Scarba [Inner Hebrides]). Respective arrays consisted of 7 and 11 moorings containing two C-PODs each and were deployed for up to 55 days. Minimum inter-mooring distances varied between 300-600 m. All C-POD data were analysed at a temporal resolution of whole minutes, with each minute classified as 1 or 0 on the basis of presence/absence of porpoise click trains (Porpoise-Positive Minutes/PPMs). Porpoise detection rates were analysed using Generalised Additive Models (GAMs) with Generalised Estimation Equations (GEEs). Although there were many porpoise detections (wave test site: N=3,432; tidal-stream site: N=17,366), daily detection rates varied significantly within both arrays. Within the wave site array (<1 km diameter), average daily detection rates varied from 4.3 to 14.8 PPMs/day. Within the tidal-stream array (<2 km diameter), average daily detection rates varied from 10.3 to 49.7 PPMs/day. GAM-GEE model results for individual moorings within both arrays indicated linkages between porpoise presence and small-scale heterogeneity among different environmental covariates (e.g., tidal phase, time of day). Porpoise detection rates varied considerably but with coherent patterns between moorings only several hundred metres apart and within hours. These patterns presumably have ecological relevance. These results indicate that, in energetically active and heterogeneous areas, porpoises can display significant spatiotemporal variability in site use at scales of hundreds of metres and hours. Such variability will not be identified when using solitary moored PAM detectors (a common practice for site-based cetacean monitoring), but may be highly relevant for site-based impact assessments of MRED and other coastal developments. PAM arrays encompassing several detectors spread across a site therefore appear to be a more appropriate tool to study site-specific cetacean use of spatiotemporally heterogeneous habitat and assess the potential impacts of coastal and nearshore developments at small scales.

Attention deficits after aneurysmal subarachnoid hemorrhage measured using the test of variables of attention.

PubMed

Wallmark, Svante; Lundström, Erik; Wikström, Johan; Ronne-Engström, Elisabeth

2015-05-01

The aim of this pilot study was to assess attention deficits in patients with aneurysmal subarachnoid hemorrhage using the test of variables of attention (TOVA). This is a computer-based continuous performance test providing objective measures of attention. We also compared the TOVA results with the attention and concentration domains of Montgomery Åsberg Depression Rating Scale and Montreal cognitive assessment, 2 examiner-administrated neuropsychological instruments. Nineteen patients with moderate to good recovery (Glasgow outcome scale, 4-5) were assessed using the TOVA, Montgomery Åsberg Depression Rating Scale, and Montreal cognitive assessment. The measurements were done when the patients visited the hospital for a routine magnetic resonance imaging control of the aneurysm. TOVA performance was pathological in 58%. The dominating pattern was a worsening of performance in the second half of the test, commonly a failing to react to correct stimuli. We found no correlation between TOVA and the performance in concentration and attention domains of Montgomery Åsberg Depression Rating Scale and Montreal cognitive assessment. Attention deficits, measured by the TOVA, were common after subarachnoid hemorrhage. This should be further studied to improve outcome. © 2015 American Heart Association, Inc.

A Hybrid Fuzzy Model for Lean Product Development Performance Measurement

NASA Astrophysics Data System (ADS)

Osezua Aikhuele, Daniel; Mohd Turan, Faiz

2016-02-01

In the effort for manufacturing companies to meet up with the emerging consumer demands for mass customized products, many are turning to the application of lean in their product development process, and this is gradually moving from being a competitive advantage to a necessity. However, due to lack of clear understanding of the lean performance measurements, many of these companies are unable to implement and fully integrated the lean principle into their product development process. Extensive literature shows that only few studies have focus systematically on the lean product development performance (LPDP) evaluation. In order to fill this gap, the study therefore proposed a novel hybrid model based on Fuzzy Reasoning Approach (FRA), and the extension of Fuzzy-AHP and Fuzzy-TOPSIS methods for the assessment of the LPDP. Unlike the existing methods, the model considers the importance weight of each of the decision makers (Experts) since the performance criteria/attributes are required to be rated, and these experts have different level of expertise. The rating is done using a new fuzzy Likert rating scale (membership-scale) which is designed such that it can address problems resulting from information lost/distortion due to closed-form scaling and the ordinal nature of the existing Likert scale.

Multi-sparse dictionary colorization algorithm based on the feature classification and detail enhancement

NASA Astrophysics Data System (ADS)

Yan, Dan; Bai, Lianfa; Zhang, Yi; Han, Jing

2018-02-01

For the problems of missing details and performance of the colorization based on sparse representation, we propose a conceptual model framework for colorizing gray-scale images, and then a multi-sparse dictionary colorization algorithm based on the feature classification and detail enhancement (CEMDC) is proposed based on this framework. The algorithm can achieve a natural colorized effect for a gray-scale image, and it is consistent with the human vision. First, the algorithm establishes a multi-sparse dictionary classification colorization model. Then, to improve the accuracy rate of the classification, the corresponding local constraint algorithm is proposed. Finally, we propose a detail enhancement based on Laplacian Pyramid, which is effective in solving the problem of missing details and improving the speed of image colorization. In addition, the algorithm not only realizes the colorization of the visual gray-scale image, but also can be applied to the other areas, such as color transfer between color images, colorizing gray fusion images, and infrared images.

Usefulness and Reliability of Tanner Pubertal Self-Rating to Urban Black Adolescents in South Africa

ERIC Educational Resources Information Center

Norris, Shane A.; Richter, Linda M.

2005-01-01

Self-rating of pubertal development is the recommended method to assess puberty in large community-based surveys of adolescent development and behavior. The aim of this study was to validate for the first time pubertal self-assessment using the sexual maturation scale developed by Tanner among Black South African adolescents (n=182) aged between…

Cybernetic modeling based on pathway analysis for Penicillium chrysogenum fed-batch fermentation.

PubMed

Geng, Jun; Yuan, Jingqi

2010-08-01

A macrokinetic model employing cybernetic methodology is proposed to describe mycelium growth and penicillin production. Based on the primordial and complete metabolic network of Penicillium chrysogenum found in the literature, the modeling procedure is guided by metabolic flux analysis and cybernetic modeling framework. The abstracted cybernetic model describes the transients of the consumption rates of the substrates, the assimilation rates of intermediates, the biomass growth rate, as well as the penicillin formation rate. Combined with the bioreactor model, these reaction rates are linked with the most important state variables, i.e., mycelium, substrate and product concentrations. Simplex method is used to estimate the sensitive parameters of the model. Finally, validation of the model is carried out with 20 batches of industrial-scale penicillin cultivation.

Leo Szilard Lectureship Award Talk - Universal Scaling Laws from Cells to Cities; A Physicist's Search for Quantitative, Unified Theories of Biological and Social Structure and Dynamics

NASA Astrophysics Data System (ADS)

West, Geoffrey

2013-04-01

Many of the most challenging, exciting and profound questions facing science and society, from the origins of life to global sustainability, fall under the banner of ``complex adaptive systems.'' This talk explores how scaling can be used to begin to develop physics-inspired quantitative, predictive, coarse-grained theories for understanding their structure, dynamics and organization based on underlying mathematisable principles. Remarkably, most physiological, organisational and life history phenomena in biology and socio-economic systems scale in a simple and ``universal'' fashion: metabolic rate scales approximately as the 3/4-power of mass over 27 orders of magnitude from complex molecules to the largest organisms. Time-scales (such as lifespans and growth-rates) and sizes (such as genome lengths and RNA densities) scale with exponents which are typically simple multiples of 1/4, suggesting that fundamental constraints underlie much of the generic structure and dynamics of living systems. These scaling laws follow from dynamical and geometrical properties of space-filling, fractal-like, hierarchical branching networks, presumed optimised by natural selection. This leads to a general framework that potentially captures essential features of diverse systems including vasculature, ontogenetic growth, cancer, aging and mortality, sleep, cell size, and DNA nucleotide substitution rates. Cities and companies also scale: wages, profits, patents, crime, disease, pollution, road lengths scale similarly across the globe, reflecting underlying universal social network dynamics which point to general principles of organization transcending their individuality. These have dramatic implications for global sustainability: innovation and wealth creation that fuel social systems, left unchecked, potentially sow the seeds for their inevitable collapse.

Uncertainties in TRMM-Era multisatellite-based tropical rainfall estimates over the Maritime Continent

NASA Astrophysics Data System (ADS)

Rauniyar, S. P.; Protat, A.; Kanamori, H.

2017-05-01

This study investigates the regional and seasonal rainfall rate retrieval uncertainties within nine state-of-the-art satellite-based rainfall products over the Maritime Continent (MC) region. The results show consistently larger differences in mean daily rainfall among products over land, especially over mountains and along coasts, compared to over ocean, by about 20% for low to medium rain rates and 5% for heavy rain rates. However, rainfall differences among the products do not exhibit any seasonal dependency over both surface types (land and ocean) of the MC region. The differences between products largely depends on the rain rate itself, with a factor 2 difference for light rain and 30% for intermediate and high rain rates over ocean. The rain-rate products dominated by microwave measurements showed less spread among themselves over ocean compared to the products dominated by infrared measurements. Conversely, over land, the rain gauge-adjusted post-real-time products dominated by microwave measurements produced the largest spreads, due to the usage of different gauge analyses for the bias corrections. Intercomparisons of rainfall characteristics of these products revealed large discrepancies in detecting the frequency and intensity of rainfall. These satellite products are finally evaluated at subdaily, daily, monthly, intraseasonal, and seasonal temporal scales against high-quality gridded rainfall observations in the Sarawak (Malaysia) region for the 4 year period 2000-2003. No single satellite-based rainfall product clearly outperforms the other products at all temporal scales. General guidelines are provided for selecting a product that could be best suited for a particular application and/or temporal resolution.

Body mass scaling of passive oxygen diffusion in endotherms and ectotherms

PubMed Central

Gillooly, James F.; Gomez, Juan Pablo; Mavrodiev, Evgeny V.; Rong, Yue; McLamore, Eric S.

2016-01-01

The area and thickness of respiratory surfaces, and the constraints they impose on passive oxygen diffusion, have been linked to differences in oxygen consumption rates and/or aerobic activity levels in vertebrates. However, it remains unclear how respiratory surfaces and associated diffusion rates vary with body mass across vertebrates, particularly in relation to the body mass scaling of oxygen consumption rates. Here we address these issues by first quantifying the body mass dependence of respiratory surface area and respiratory barrier thickness for a diversity of endotherms (birds and mammals) and ectotherms (fishes, amphibians, and reptiles). Based on these findings, we then use Fick’s law to predict the body mass scaling of oxygen diffusion for each group. Finally, we compare the predicted body mass dependence of oxygen diffusion to that of oxygen consumption in endotherms and ectotherms. We find that the slopes and intercepts of the relationships describing the body mass dependence of passive oxygen diffusion in these two groups are statistically indistinguishable from those describing the body mass dependence of oxygen consumption. Thus, the area and thickness of respiratory surfaces combine to match oxygen diffusion capacity to oxygen consumption rates in both air- and water-breathing vertebrates. In particular, the substantially lower oxygen consumption rates of ectotherms of a given body mass relative to those of endotherms correspond to differences in oxygen diffusion capacity. These results provide insights into the long-standing effort to understand the structural attributes of organisms that underlie the body mass scaling of oxygen consumption. PMID:27118837

Body mass scaling of passive oxygen diffusion in endotherms and ectotherms.

PubMed

Gillooly, James F; Gomez, Juan Pablo; Mavrodiev, Evgeny V; Rong, Yue; McLamore, Eric S

2016-05-10

The area and thickness of respiratory surfaces, and the constraints they impose on passive oxygen diffusion, have been linked to differences in oxygen consumption rates and/or aerobic activity levels in vertebrates. However, it remains unclear how respiratory surfaces and associated diffusion rates vary with body mass across vertebrates, particularly in relation to the body mass scaling of oxygen consumption rates. Here we address these issues by first quantifying the body mass dependence of respiratory surface area and respiratory barrier thickness for a diversity of endotherms (birds and mammals) and ectotherms (fishes, amphibians, and reptiles). Based on these findings, we then use Fick's law to predict the body mass scaling of oxygen diffusion for each group. Finally, we compare the predicted body mass dependence of oxygen diffusion to that of oxygen consumption in endotherms and ectotherms. We find that the slopes and intercepts of the relationships describing the body mass dependence of passive oxygen diffusion in these two groups are statistically indistinguishable from those describing the body mass dependence of oxygen consumption. Thus, the area and thickness of respiratory surfaces combine to match oxygen diffusion capacity to oxygen consumption rates in both air- and water-breathing vertebrates. In particular, the substantially lower oxygen consumption rates of ectotherms of a given body mass relative to those of endotherms correspond to differences in oxygen diffusion capacity. These results provide insights into the long-standing effort to understand the structural attributes of organisms that underlie the body mass scaling of oxygen consumption.

Catchment-scale groundwater recharge and vegetation water use efficiency

NASA Astrophysics Data System (ADS)

Troch, P. A. A.; Dwivedi, R.; Liu, T.; Meira, A.; Roy, T.; Valdés-Pineda, R.; Durcik, M.; Arciniega, S.; Brena-Naranjo, J. A.

2017-12-01

Precipitation undergoes a two-step partitioning when it falls on the land surface. At the land surface and in the shallow subsurface, rainfall or snowmelt can either runoff as infiltration/saturation excess or quick subsurface flow. The rest will be stored temporarily in the root zone. From the root zone, water can leave the catchment as evapotranspiration or percolate further and recharge deep storage (e.g. fractured bedrock aquifer). Quantifying the average amount of water that recharges deep storage and sustains low flows is extremely challenging, as we lack reliable methods to quantify this flux at the catchment scale. It was recently shown, however, that for semi-arid catchments in Mexico, an index of vegetation water use efficiency, i.e. the Horton index (HI), could predict deep storage dynamics. Here we test this finding using 247 MOPEX catchments across the conterminous US, including energy-limited catchments. Our results show that the observed HI is indeed a reliable predictor of deep storage dynamics in space and time. We further investigate whether the HI can also predict average recharge rates across the conterminous US. We find that the HI can reliably predict the average recharge rate, estimated from the 50th percentile flow of the flow duration curve. Our results compare favorably with estimates of average recharge rates from the US Geological Survey. Previous research has shown that HI can be reliably estimated based on aridity index, mean slope and mean elevation of a catchment (Voepel et al., 2011). We recalibrated Voepel's model and used it to predict the HI for our 247 catchments. We then used these predicted values of the HI to estimate average recharge rates for our catchments, and compared them with those estimated from observed HI. We find that the accuracies of our predictions based on observed and predicted HI are similar. This provides an estimation method of catchment-scale average recharge rates based on easily derived catchment characteristics, such as climate and topography, and free of discharge measurements.

Scaling of number, size, and metabolic rate of cells with body size in mammals.

PubMed

Savage, Van M; Allen, Andrew P; Brown, James H; Gillooly, James F; Herman, Alexander B; Woodruff, William H; West, Geoffrey B

2007-03-13

The size and metabolic rate of cells affect processes from the molecular to the organismal level. We present a quantitative, theoretical framework for studying relationships among cell volume, cellular metabolic rate, body size, and whole-organism metabolic rate that helps reveal the feedback between these levels of organization. We use this framework to show that average cell volume and average cellular metabolic rate cannot both remain constant with changes in body size because of the well known body-size dependence of whole-organism metabolic rate. Based on empirical data compiled for 18 cell types in mammals, we find that many cell types, including erythrocytes, hepatocytes, fibroblasts, and epithelial cells, follow a strategy in which cellular metabolic rate is body size dependent and cell volume is body size invariant. We suggest that this scaling holds for all quickly dividing cells, and conversely, that slowly dividing cells are expected to follow a strategy in which cell volume is body size dependent and cellular metabolic rate is roughly invariant with body size. Data for slowly dividing neurons and adipocytes show that cell volume does indeed scale with body size. From these results, we argue that the particular strategy followed depends on the structural and functional properties of the cell type. We also discuss consequences of these two strategies for cell number and capillary densities. Our results and conceptual framework emphasize fundamental constraints that link the structure and function of cells to that of whole organisms.

Enhancing Treatment Team Process through Mindfulness-Based Mentoring in an Inpatient Psychiatric Hospital

ERIC Educational Resources Information Center

Singh, Nirbhay N.; Singh, Subhashni D.; Sabaawi, Mohamed; Myers, Rachel E.; Wahler, Robert G.

2006-01-01

The authors investigated changes in treatment team functioning in an adult inpatient psychiatric hospital after the implementation of a mindfulness-based mentoring intervention. Using a multiple baseline across treatment teams design, the authors assessed levels of functioning of three treatment teams using a 50-item rating scale and then…

VALIDATION OF ADULT OMNI PERCEIVED EXERTION SCALES FOR ELLIPTICAL ERGOMETRY12

PubMed Central

MAYS, RYAN J.; GOSS, FREDRIC L.; SCHAFER, MARK A.; KIM, KEVIN H.; NAGLE-STILLEY, ELIZABETH F.; ROBERTSON, ROBERT J.

2012-01-01

Summary This investigation examined the validity of newly developed Adult OMNI Elliptical Ergometer Ratings of Perceived Exertion Scales. Sixty men and women performed a graded exercise test on an elliptical ergometer. Oxygen consumption (VO2), heart rate (HR) and ratings of perceived exertion were recorded each stage from the Borg 15 Category Scale and two different OMNI scales. One scale employed an elliptical ergometer format of the OMNI Picture System of Perceived Exertion. The second scale modified verbal, numerical, and pictorial descriptors at the low end of the response range. Concurrent and construct validity were established by the positive relation between ratings of perceived exertion from each OMNI scale with VO2, HR and Borg Scale ratings of perceived exertion (men, r = .94–.97; women, r = .93–.98). Validity was established for both OMNI scales, indicating either metric can be used to estimate ratings of perceived exertion during partial weight bearing exercise. PMID:21319623

A two-scale model for dynamic damage evolution

NASA Astrophysics Data System (ADS)

Keita, Oumar; Dascalu, Cristian; François, Bertrand

2014-03-01

This paper presents a new micro-mechanical damage model accounting for inertial effect. The two-scale damage model is fully deduced from small-scale descriptions of dynamic micro-crack propagation under tensile loading (mode I). An appropriate micro-mechanical energy analysis is combined with homogenization based on asymptotic developments in order to obtain the macroscopic evolution law for damage. Numerical simulations are presented in order to illustrate the ability of the model to describe known behaviors like size effects for the structural response, strain-rate sensitivity, brittle-ductile transition and wave dispersion.

Aspects of Predisposition to Assertiveness, Resistance to Assertiveness and Insight into Assertiveness Based Upon Race and Sex.

DTIC Science & Technology

1977-12-15

reflecting assertive behavior are presented to the subjects and (b) the subjects respond by using a scale that permits him or her to indicate his...responses of sub— - jects are not assessed in terms of how assertive ~j~y perceive them to be. For example, an item might ask a subject to scale how...possible actions. This time we want you to tell us how strong or assertive each action is, in your opinion. Each action can be rated on a scale from 1 to 5

Validation of Empirically Derived Rating Scales for a Story Retelling Speaking Test

ERIC Educational Resources Information Center

Hirai, Akiyo; Koizumi, Rie

2013-01-01

In recognition of the rating scale as a crucial tool of performance assessment, this study aims to establish a rating scale suitable for a Story Retelling Speaking Test (SRST), which is a semidirect test of speaking ability in English as a foreign language for classroom use. To identify an appropriate scale, three rating scales, all of which have…

Carrier density independent scattering rate in SrTiO₃-based electron liquids

DOE PAGES

Mikheev, Evgeny; Raghavan, Santosh; Zhang, Jack Y.; ...

2016-02-10

We examine the carrier density dependence of the scattering rate in two- and three-dimensional electron liquids in SrTiO 3 in the regime where it scales with T n (T is the temperature and n ≤ 2) in the cases when it is varied by electrostatic control and chemical doping, respectively. It is shown that the scattering rate is independent of the carrier density. This is contrary to the expectations from Landau Fermi liquid theory, where the scattering rate scales inversely with the Fermi energy (E F). We discuss that the behavior is very similar to systems traditionally identified as non-Fermimore » liquids (n < 2). This includes the cuprates and other transition metal oxide perovskites, where strikingly similar density independent scattering rates have been observed. Ultimately, the results indicate that the applicability of Fermi liquid theory should be questioned for a much broader range of correlated materials and point to the need for a unified theory.« less

Hemiparesis is a clinical correlate of general adaptive dysfunction in children and adolescents with Sturge-Weber syndrome.

PubMed

Reesman, Jennifer; Gray, Robert; Suskauer, Stacy J; Ferenc, Lisa M; Kossoff, Eric H; Lin, Doris D M; Turin, Elizabeth; Comi, Anne M; Brice, Patrick J; Zabel, T Andrew

2009-06-01

This study sought to identify neurologic correlates of adaptive functioning in individuals with Sturge-Weber syndrome. A total of 18 children, adolescents, and young adults with Sturge-Weber syndrome with brain involvement were recruited from our Sturge-Weber center. All underwent neurologic examination (including review of clinical brain magnetic resonance imaging) and neuropsychological assessment. Neuropsychological assessment included measures of intellectual ability and standardized parent report of adaptive functioning. Overall, Full Scale IQ and ratings of global adaptive functioning were both lower than the population-based norms (P < .05). Negative correlations were identified between adaptive functioning ratings, clinician ratings of cortical abnormality, and ratings of neurologic status. Hemiparesis (minimal versus prominent) was the only individual component of the rating scales that differentiated between individuals with nonimpaired and impaired adaptive functioning scores. Information obtained during neurological examination of children and adolescents with Sturge-Weber syndrome particularly hemiparetic status is useful for identifying children who may need additional intervention.

Carrier density independent scattering rate in SrTiO3-based electron liquids

PubMed Central

Mikheev, Evgeny; Raghavan, Santosh; Zhang, Jack Y.; Marshall, Patrick B.; Kajdos, Adam P.; Balents, Leon; Stemmer, Susanne

2016-01-01

We examine the carrier density dependence of the scattering rate in two- and three-dimensional electron liquids in SrTiO3 in the regime where it scales with Tn (T is the temperature and n ≤ 2) in the cases when it is varied by electrostatic control and chemical doping, respectively. It is shown that the scattering rate is independent of the carrier density. This is contrary to the expectations from Landau Fermi liquid theory, where the scattering rate scales inversely with the Fermi energy (EF). We discuss that the behavior is very similar to systems traditionally identified as non-Fermi liquids (n < 2). This includes the cuprates and other transition metal oxide perovskites, where strikingly similar density-independent scattering rates have been observed. The results indicate that the applicability of Fermi liquid theory should be questioned for a much broader range of correlated materials and point to the need for a unified theory. PMID:26861764

A study of the viability of exploiting memory content similarity to improve resilience to memory errors

DOE PAGES

Levy, Scott; Ferreira, Kurt B.; Bridges, Patrick G.; ...

2014-12-09

Building the next-generation of extreme-scale distributed systems will require overcoming several challenges related to system resilience. As the number of processors in these systems grow, the failure rate increases proportionally. One of the most common sources of failure in large-scale systems is memory. In this paper, we propose a novel runtime for transparently exploiting memory content similarity to improve system resilience by reducing the rate at which memory errors lead to node failure. We evaluate the viability of this approach by examining memory snapshots collected from eight high-performance computing (HPC) applications and two important HPC operating systems. Based on themore » characteristics of the similarity uncovered, we conclude that our proposed approach shows promise for addressing system resilience in large-scale systems.« less

From minerals to hillslopes: Towards an integrated framework for interpreting chemical and physical erosion

NASA Astrophysics Data System (ADS)

Hahm, W.; Riebe, C. S.; Ferrier, K.; Kirchner, J. W.

2011-12-01

Traditional frameworks for conceptualizing hillslope denudation distinguish between the movement of mass in solution (chemical erosion) and mass moved via mechanical processes (physical erosion). At the hillslope scale, physical and chemical erosion rates can be quantified by combining measurements of regolith chemistry with cosmogenic nuclide concentrations in bedrock and sediment, while basin-scale rates are often inferred from riverine solute and sediment loads. These techniques integrate the effects of numerous weathering and erosion mechanisms and do not provide prima facie information about the precise nature and scale of those mechanisms. For insight into erosional process, physical erosion has been considered in terms of two limiting regimes. When physical erosion outpaces weathering front advance, regolith is mobilized downslope as soon as it is sufficiently loosened by weathering, and physical erosion rates are limited by rates of mobile regolith production. This is commonly termed weathering-limited erosion. Conversely, when weathering front advance outpaces erosion, the mobile regolith layer grows thicker over time, and physical erosion rates are limited by the efficiency of downslope transport processes. This is termed transport-limited erosion. This terminology brings the description of hillslope evolution closer to the realm of essential realism, to the extent that measurable quantities from the field can be cast in a process-based framework. An analogous process-limitation framework describes chemical erosion. In supply-limited chemical erosion, chemical weathering depletes regolith of its reactive phases during residence on a hillslope, and chemical erosion rates are limited by the supply of fresh minerals to the weathering zone. Alternatively, hillslopes may exhibit kinetic-limited chemical erosion, where physical erosion transports regolith downslope before weatherable phases are completely removed by chemical erosion. We show how supply- and kinetic-limited chemical erosion can be distinguished from one another using data from a global compilation of physical and chemical erosion rates. As a step towards understanding these rates at the level of essential realism, we explore how the hillslope-scale regimes of supply- and kinetic-limited chemical erosion relate to existing conceptual frameworks that interpret weathering rates in terms of transport- and kinetic-limitation at the mineral scale.

Seeing the Forest for the Trees: Prevalence of Low Scores on the Wechsler Intelligence Scale for Children, Fourth Edition (WISC-IV)

ERIC Educational Resources Information Center

Brooks, Brian L.

2010-01-01

Low scores across a battery of tests are common in healthy people and vary by demographic characteristics. The purpose of the present article was to present the base rates of low scores for the Wechsler Intelligence Scale for Children, fourth edition (WISC-IV; D. Wechsler, 2003). Participants included 2,200 children and adolescents between 6 and…

Effect of pipe corrosion scales on chlorine dioxide consumption in drinking water distribution systems.

PubMed

Zhang, Zhe; Stout, Janet E; Yu, Victor L; Vidic, Radisav

2008-01-01

Previous studies showed that temperature and total organic carbon in drinking water would cause chlorine dioxide (ClO(2)) loss in a water distribution system and affect the efficiency of ClO(2) for Legionella control. However, among the various causes of ClO(2) loss in a drinking water distribution system, the loss of disinfectant due to the reaction with corrosion scales has not been studied in detail. In this study, the corrosion scales from a galvanized iron pipe and a copper pipe that have been in service for more than 10 years were characterized by energy dispersive spectroscopy (EDS) and X-ray diffraction (XRD). The impact of these corrosion scale materials on ClO(2) decay was investigated in de-ionized water at 25 and 45 degrees C in a batch reactor with floating glass cover. ClO(2) decay was also investigated in a specially designed reactor made from the iron and copper pipes to obtain more realistic reaction rate data. Goethite (alpha-FeOOH) and magnetite (Fe(3)O(4)) were identified as the main components of iron corrosion scale. Cuprite (Cu(2)O) was identified as the major component of copper corrosion scale. The reaction rate of ClO(2) with both iron and copper oxides followed a first-order kinetics. First-order decay rate constants for ClO(2) reactions with iron corrosion scales obtained from the used service pipe and in the iron pipe reactor itself ranged from 0.025 to 0.083 min(-1). The decay rate constant for ClO(2) with Cu(2)O powder and in the copper pipe reactor was much smaller and it ranged from 0.0052 to 0.0062 min(-1). Based on these results, it can be concluded that the corrosion scale will cause much more significant ClO(2) loss in corroded iron pipes of the distribution system than the total organic carbon that may be present in finished water.

Assessment of fine-scale parameterizations of turbulent dissipation rates in the Southern Ocean

NASA Astrophysics Data System (ADS)

Takahashi, A.; Hibiya, T.

2016-12-01

To sustain the global overturning circulation, more mixing is required in the ocean than has been observed. The most likely candidates for this missing mixing are breaking of wind-induced near-inertial waves and bottom-generated internal lee waves in the sparsely observed Southern Ocean. Nevertheless, there is a paucity of direct microstructure measurements in the Southern Ocean where energy dissipation rates have been estimated mostly using fine-scale parameterizations. In this study, we assess the validity of the existing fine-scale parameterizations in the Antarctic Circumpolar Current (ACC) region using the data obtained from simultaneous full-depth measurements of micro-scale turbulence and fine-scale shear/strain carried out south of Australia during January 17 to February 2, 2016. Although the fine-scale shear/strain ratio (Rω) is close to the Garrett-Munk (GM) value at the station north of Subtropical Front, the values of Rω at the stations south of Subantarctic Front well exceed the GM value, suggesting that the local internal wave spectra are significantly biased to lower frequencies. We find that not all of the observed energy dissipation rates at these locations are well predicted using Gregg-Henyey-Polzin (GHP; Gregg et al., 2003) and Ijichi-Hibiya (IH; Ijichi and Hibiya, 2015) parameterizations, both of which take into account the spectral distortion in terms of Rω; energy dissipation rates at some locations are obviously overestimated by GHP and IH, although only the strain-based Wijesekera (Wijesekera et al., 1993) parameterization yields fairly good predictions. One possible explanation for this result is that a significant portion of the observed shear variance at these locations might be attributed to kinetic-energy-dominant small-scale eddies associated with the ACC, so that fine-scale strain rather than Rω becomes a more appropriate parameter to characterize the actual internal wave field.

Experimental Comparison of Calcium Sulfate (CaSO(4)) Scale Deposition on Coated Carbon Steel and Titanium Surfaces

NASA Astrophysics Data System (ADS)

Al-Otaibi, Dhawi AbdulRahman

Calcium Sulfate (CaSO4) deposit reduces heat exchange in heat transfer equipment which adversely affects the equipment performance and plant production. This experimental study was conducted by using the Rotating Cylinder Electrode (RCE) equipment available in the university's Center for Engineering Research (CER/RI) to study and compare the effect of solution hydrodynamics on Calcium Sulfate (CaSO4) scale deposition on coated carbon steel and titanium surfaces. In addition, the Scanning Electron Microscopic was used to examine the morphology and distribution of Calcium Sulfate (CaSO 4) crystals deposited on titanium metal surfaces. In this study, the rotational speed was varied from 100 to 2000 RPM to study the behavior of Calcium Sulfate (CaSO4) accumulation on both materials. Based on the experimental results, Calcium Sulfate (CaSO4) scale obtained in the present study was almost constant on coated carbon steel in which the rate of scale deposition is equal to the rate of scale removal. However, the deposition of Calcium Sulfate (CaSO4) observed on titanium material was increased as the speed increased.

Trickle-bed root culture bioreactor design and scale-up: growth, fluid-dynamics, and oxygen mass transfer.

PubMed

Ramakrishnan, Divakar; Curtis, Wayne R

2004-10-20

Trickle-bed root culture reactors are shown to achieve tissue concentrations as high as 36 g DW/L (752 g FW/L) at a scale of 14 L. Root growth rate in a 1.6-L reactor configuration with improved operational conditions is shown to be indistinguishable from the laboratory-scale benchmark, the shaker flask (mu=0.33 day(-1)). These results demonstrate that trickle-bed reactor systems can sustain tissue concentrations, growth rates and volumetric biomass productivities substantially higher than other reported bioreactor configurations. Mass transfer and fluid dynamics are characterized in trickle-bed root reactors to identify appropriate operating conditions and scale-up criteria. Root tissue respiration goes through a minimum with increasing liquid flow, which is qualitatively consistent with traditional trickle-bed performance. However, liquid hold-up is much higher than traditional trickle-beds and alternative correlations based on liquid hold-up per unit tissue mass are required to account for large changes in biomass volume fraction. Bioreactor characterization is sufficient to carry out preliminary design calculations that indicate scale-up feasibility to at least 10,000 liters.

Performance-based measures and behavioral ratings of executive function in diagnosing attention-deficit/hyperactivity disorder in children.

PubMed

Tan, Alexander; Delgaty, Lauren; Steward, Kayla; Bunner, Melissa

2018-04-16

Deficits in real-world executive functioning (EF) are a frequent characteristic of attention-deficit/hyperactivity disorder (ADHD). However, the predictive value of using performance-based and behavioral rating measures of EF when diagnosing ADHD remains unclear. The current study investigates the use of performance-based EF measures and a parent-report questionnaire with established ecological validity and clinical utility when diagnosing ADHD. Participants included 21 healthy controls, 21 ADHD-primary inattentive, and 21 ADHD-combined type subjects aged 6-15 years. A brief neuropsychological battery was administered to each subject including common EF assessment measures. Significant differences were not found between groups on most performance-based EF measures, whereas significant differences (p < 0.05) were found on most parent-report behavioral rating scales. Furthermore, performance-based measures did not predict group membership above chance levels. Results further support differences in predictive value of EF performance-based measures compared to parent-report questionnaires when diagnosing ADHD. Further research must investigate the relationship between performance-based and behavioral rating measures when assessing EF in ADHD.

A predictive multi-linear regression model for organic micropollutants, based on a laboratory-scale column study simulating the river bank filtration process.

PubMed

Bertelkamp, C; Verliefde, A R D; Reynisson, J; Singhal, N; Cabo, A J; de Jonge, M; van der Hoek, J P

2016-03-05

This study investigated relationships between OMP biodegradation rates and the functional groups present in the chemical structure of a mixture of 31 OMPs. OMP biodegradation rates were determined from lab-scale columns filled with soil from RBF site Engelse Werk of the drinking water company Vitens in The Netherlands. A statistically significant relationship was found between OMP biodegradation rates and the functional groups of the molecular structures of OMPs in the mixture. The OMP biodegradation rate increased in the presence of carboxylic acids, hydroxyl groups, and carbonyl groups, but decreased in the presence of ethers, halogens, aliphatic ethers, methyl groups and ring structures in the chemical structure of the OMPs. The predictive model obtained from the lab-scale soil column experiment gave an accurate qualitative prediction of biodegradability for approximately 70% of the OMPs monitored in the field (80% excluding the glymes). The model was found to be less reliable for the more persistent OMPs (OMPs with predicted biodegradation rates lower or around the standard error=0.77d(-1)) and OMPs containing amide or amine groups. These OMPs should be carefully monitored in the field to determine their removal during RBF. Copyright © 2015 Elsevier B.V. All rights reserved.

Validity of the MCMI Drug Abuse Scale varies as a function of drug choice, race, and axis II subtypes.

PubMed

Calsyn, D A; Saxon, A J; Daisy, F

1991-06-01

The validity of the Drug Abuse Scale (T) from the Million Clinical Multiaxial Inventory (MCMI) was studied by administering the MCMI to 110 male veterans seeking treatment for opioid or cocaine dependence. Only 26 and 23% of the sample obtained base rate (BR) scores above the clinical relevant cutoffs of 84 and 74, respectively. Covariables associated with elevated scores on the T Scale were Black race, presence of narcissistic/antisocial personality features, and more severe psychopathology in general. The authors urge caution in using the Drug Abuse Scale for the purpose of identifying drug abusers.

Comparison of Rating Scales in the Development of Patient-Reported Outcome Measures for Children with Eye Disorders.

PubMed

Hatt, Sarah R; Leske, David A; Wernimont, Suzanne M; Birch, Eileen E; Holmes, Jonathan M

2017-03-01

A rating scale is a critical component of patient-reported outcome instrument design, but the optimal rating scale format for pediatric use has not been investigated. We compared rating scale performance when administering potential questionnaire items to children with eye disorders and their parents. Three commonly used rating scales were evaluated: frequency (never, sometimes, often, always), severity (not at all, a little, some, a lot), and difficulty (not difficult, a little difficult, difficult, very difficult). Ten patient-derived items were formatted for each rating scale, and rating scale testing order was randomized. Both child and parent were asked to comment on any problems with, or a preference for, a particular scale. Any confusion about options or inability to answer was recorded. Twenty-one children, aged 5-17 years, with strabismus, amblyopia, or refractive error were recruited, each with one of their parents. Of the first 10 children, 4 (40%) had problems using the difficulty scale, compared with 1 (10%) using frequency, and none using severity. The difficulty scale was modified, replacing the word "difficult" with "hard." Eleven additional children (plus parents) then completed all 3 questionnaires. No children had problems using any scale. Four (36%) parents had problems using the difficulty ("hard") scale and 1 (9%) with frequency. Regarding preference, 6 (55%) of 11 children and 5 (50%) of 10 parents preferred using the frequency scale. Children and parents found the frequency scale and question format to be the most easily understood. Children and parents also expressed preference for the frequency scale, compared with the difficulty and severity scales. We recommend frequency rating scales for patient-reported outcome measures in pediatric populations.

Ship detection using STFT sea background statistical modeling for large-scale oceansat remote sensing image

NASA Astrophysics Data System (ADS)

Wang, Lixia; Pei, Jihong; Xie, Weixin; Liu, Jinyuan

2018-03-01

Large-scale oceansat remote sensing images cover a big area sea surface, which fluctuation can be considered as a non-stationary process. Short-Time Fourier Transform (STFT) is a suitable analysis tool for the time varying nonstationary signal. In this paper, a novel ship detection method using 2-D STFT sea background statistical modeling for large-scale oceansat remote sensing images is proposed. First, the paper divides the large-scale oceansat remote sensing image into small sub-blocks, and 2-D STFT is applied to each sub-block individually. Second, the 2-D STFT spectrum of sub-blocks is studied and the obvious different characteristic between sea background and non-sea background is found. Finally, the statistical model for all valid frequency points in the STFT spectrum of sea background is given, and the ship detection method based on the 2-D STFT spectrum modeling is proposed. The experimental result shows that the proposed algorithm can detect ship targets with high recall rate and low missing rate.

Mammalian basal metabolic rate is proportional to body mass2/3

PubMed Central

White, Craig R.; Seymour, Roger S.

2003-01-01

The relationship between mammalian basal metabolic rate (BMR, ml of O2 per h) and body mass (M, g) has been the subject of regular investigation for over a century. Typically, the relationship is expressed as an allometric equation of the form BMR = aMb. The scaling exponent (b) is a point of contention throughout this body of literature, within which arguments for and against geometric (b = 2/3) and quarter-power (b = 3/4) scaling are made and rebutted. Recently, interest in the topic has been revived by published explanations for quarter-power scaling based on fractal nutrient supply networks and four-dimensional biology. Here, a new analysis of the allometry of mammalian BMR that accounts for variation associated with body temperature, digestive state, and phylogeny finds no support for a metabolic scaling exponent of 3/4. Data encompassing five orders of magnitude variation in M and featuring 619 species from 19 mammalian orders show that BMR ∝ M2/3. PMID:12637681

Time Series of Tropical-Forest Structure from TanDEM-X, Transformed to Time Series of Biomass by MODIS

NASA Astrophysics Data System (ADS)

Treuhaft, R. N.; Baccini, A.; Goncalves, F. G.; Lei, Y.; Keller, M.; Walker, W. S.

2017-12-01

Tropical forests account for about 50% of the world's forested biomass, and play a critical role in the control of atmospheric carbon dioxide. Large-scale (1000's of km) changes in forest structure and biomass bear on global carbon source-sink dynamics, while small-scale (< 100 m) changes bear on deforestation and degradation monitoring. After describing the interferometric SAR (InSAR) phase-height observation, we show forest phase-height time series from the TanDEM-X radar interferometer at X-band (3 cm), taken with monthly and sub-hectare temporal and spatial resolution, respectively. The measurements were taken with more than 30 TanDEM-X passes over Tapajós National Forest in the Brazilian Amazon between 2011 and 2014. The transformation of phase-height rates into aboveground biomass (AGB) rates is based on the idea that the change in AGB due to a change in phase-height depends on the plot's AGB. Plots with higher AGB will produce more AGB for a given increase in height or phase-height. Postulating a power-law dependence of plot-level mass density on physical height, we previously found that the best conversion factors for transforming phase-height rate to AGB rate were indeed dependent on AGB. For 78 plots, we demonstrated AGB rates from InSAR phase-height rates using AGB from field measurements. For regional modeling of the Amazon Basin, field measurements of AGB, to specify the conversion factors, is impractical. Conversion factors from InSAR phase-height rate to AGB rate in this talk will be based on AGB derived from the Moderate Resolution Imaging Spectroradiometer (MODIS). AGB measurement from MODIS is based on the spectral reflectance of 7 bands from the visible to short wave infrared, and auxiliary metrics describing the variance in reflectance. The mapping of MODIS reflectance to AGB is enabled by training a machine learning algorithm with lidar-derived AGB data, which are in turn trained by field measurements for small areas. The performance of TanDEM-X AGB rate from MODIS-derived conversion factors will be compared to that derived from field-based conversion factors. We will also attempt to improve phase-height rate to AGB rate transformation by deriving improved models of mass density dependences on height, based on the aggregation of single-stem allometrics.

Population-Scale Sequencing Data Enable Precise Estimates of Y-STR Mutation Rates

PubMed Central

Willems, Thomas; Gymrek, Melissa; Poznik, G. David; Tyler-Smith, Chris; Erlich, Yaniv

2016-01-01

Short tandem repeats (STRs) are mutation-prone loci that span nearly 1% of the human genome. Previous studies have estimated the mutation rates of highly polymorphic STRs by using capillary electrophoresis and pedigree-based designs. Although this work has provided insights into the mutational dynamics of highly mutable STRs, the mutation rates of most others remain unknown. Here, we harnessed whole-genome sequencing data to estimate the mutation rates of Y chromosome STRs (Y-STRs) with 2–6 bp repeat units that are accessible to Illumina sequencing. We genotyped 4,500 Y-STRs by using data from the 1000 Genomes Project and the Simons Genome Diversity Project. Next, we developed MUTEA, an algorithm that infers STR mutation rates from population-scale data by using a high-resolution SNP-based phylogeny. After extensive intrinsic and extrinsic validations, we harnessed MUTEA to derive mutation-rate estimates for 702 polymorphic STRs by tracing each locus over 222,000 meioses, resulting in the largest collection of Y-STR mutation rates to date. Using our estimates, we identified determinants of STR mutation rates and built a model to predict rates for STRs across the genome. These predictions indicate that the load of de novo STR mutations is at least 75 mutations per generation, rivaling the load of all other known variant types. Finally, we identified Y-STRs with potential applications in forensics and genetic genealogy, assessed the ability to differentiate between the Y chromosomes of father-son pairs, and imputed Y-STR genotypes. PMID:27126583

Efficacy of vilazodone on anxiety symptoms in patients with major depressive disorder

PubMed Central

Chen, Dalei; Edwards, John; Ruth, Adam

2014-01-01

Anxiety symptoms are prevalent in patients with major depressive disorder. A post-hoc analysis of two phase III trials was conducted to evaluate the efficacy of vilazodone on depression-related anxiety. Using the 17-item Hamilton Depression Rating Scale (HAMD17) Anxiety/Somatization subscale, patients were classified as anxious or nonanxious. Improvements in depressive symptoms were based on least squares mean changes in HAMD17 and Montgomery–Asberg Depression Rating Scale total scores. Anxiety symptoms in the anxious subgroup were evaluated using Hamilton Anxiety Rating Scale (HAMA) total and subscale (Psychic Anxiety, Somatic Anxiety) scores, HAMD17 Anxiety/Somatization subscale and item (Psychic Anxiety, Somatic Anxiety) scores, and the Montgomery–Asberg Depression Rating Scale Inner Tension item score. Most of the pooled study population [82.0% (708/863)] was classified with anxious depression. After 8 weeks of treatment, least squares mean differences between vilazodone and placebo for changes in HAMA total and HAMD17 Anxiety/Somatization subscale scores were −1.82 (95% confidence interval −2.81 to −0.83; P<0.001) and −0.75 (95% confidence interval −1.17 to −0.32; P<0.001), respectively. Statistically significant improvements with vilazodone were also found on all other anxiety-related measures, except the HAMA Somatic Anxiety subscale. Vilazodone may be effective in treating patients with major depressive disorder who exhibit somatic and/or psychic symptoms of anxiety. PMID:24978955

Biogeochemical evidence of vigorous mixing in the abyssal ocean

NASA Astrophysics Data System (ADS)

Lampitt, Richard S.; Popova, Ekaterina E.; Tyrrell, Toby

2003-05-01

The metabolic activities of biological communities living at the abyssal seabed create a strong source of nutrients and a sink for oxygen. If the published estimates of vertical mixing based on instantaneous microstructure measurements are correct, near to the abyssal seabed away from rough topographic features there should be enhanced concentrations of nitrate and phosphate and depletion of oxygen. Recent data on the vertical concentration profiles of inorganic nutrients and oxygen over the bottom 1000 m of the water column (World Ocean Circulation Experiment - WOCE) provide no such evidence. It is concluded that the effective vertical mixing rates are much more vigorous than previously indicated and may even be higher than estimates of average basin scale rates based on temperature and salinity distributions. We propose that the enhanced mixing associated with rough topography influences the entire volume of the abyssal ocean on short time scales (e.g., one month - one year).

A fuzzy-logic-based controller for methane production in anaerobic fixed-film reactors.

PubMed

Robles, A; Latrille, E; Ruano, M V; Steyer, J P

2017-01-01

The main objective of this work was to develop a controller for biogas production in continuous anaerobic fixed-bed reactors, which used effluent total volatile fatty acids (VFA) concentration as control input in order to prevent process acidification at closed loop. To this aim, a fuzzy-logic-based control system was developed, tuned and validated in an anaerobic fixed-bed reactor at pilot scale that treated industrial winery wastewater. The proposed controller varied the flow rate of wastewater entering the system as a function of the gaseous outflow rate of methane and VFA concentration. Simulation results show that the proposed controller is capable to achieve great process stability even when operating at high VFA concentrations. Pilot results showed the potential of this control approach to maintain the process working properly under similar conditions to the ones expected at full-scale plants.

Development of building energy asset rating using stock modelling in the USA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Na; Goel, Supriya; Makhmalbaf, Atefe

2016-01-29

The US Building Energy Asset Score helps building stakeholders quickly gain insight into the efficiency of building systems (envelope, electrical and mechanical systems). A robust, easy-to-understand 10-point scoring system was developed to facilitate an unbiased comparison of similar building types across the country. The Asset Score does not rely on a database or specific building baselines to establish a rating. Rather, distributions of energy use intensity (EUI) for various building use types were constructed using Latin hypercube sampling and converted to a series of stepped linear scales to score buildings. A score is calculated based on the modelled source EUImore » after adjusting for climate. A web-based scoring tool, which incorporates an analytical engine and a simulation engine, was developed to standardize energy modelling and reduce implementation cost. This paper discusses the methodology used to perform several hundred thousand building simulation runs and develop the scoring scales.« less

Web-based training and interrater reliability testing for scoring the Hamilton Depression Rating Scale.

PubMed

Rosen, Jules; Mulsant, Benoit H; Marino, Patricia; Groening, Christopher; Young, Robert C; Fox, Debra

2008-10-30

Despite the importance of establishing shared scoring conventions and assessing interrater reliability in clinical trials in psychiatry, these elements are often overlooked. Obstacles to rater training and reliability testing include logistic difficulties in providing live training sessions, or mailing videotapes of patients to multiple sites and collecting the data for analysis. To address some of these obstacles, a web-based interactive video system was developed. It uses actors of diverse ages, gender and race to train raters how to score the Hamilton Depression Rating Scale and to assess interrater reliability. This system was tested with a group of experienced and novice raters within a single site. It was subsequently used to train raters of a federally funded multi-center clinical trial on scoring conventions and to test their interrater reliability. The advantages and limitations of using interactive video technology to improve the quality of clinical trials are discussed.

Improved turbulence models based on large eddy simulation of homogeneous, incompressible turbulent flows

NASA Technical Reports Server (NTRS)

Bardino, J.; Ferziger, J. H.; Reynolds, W. C.

1983-01-01

The physical bases of large eddy simulation and subgrid modeling are studied. A subgrid scale similarity model is developed that can account for system rotation. Large eddy simulations of homogeneous shear flows with system rotation were carried out. Apparently contradictory experimental results were explained. The main effect of rotation is to increase the transverse length scales in the rotation direction, and thereby decrease the rates of dissipation. Experimental results are shown to be affected by conditions at the turbulence producing grid, which make the initial states a function of the rotation rate. A two equation model is proposed that accounts for effects of rotation and shows good agreement with experimental results. In addition, a Reynolds stress model is developed that represents the turbulence structure of homogeneous shear flows very well and can account also for the effects of system rotation.

Simultaneous wavelength conversion of ASK and DPSK signals based on four-wave-mixing in dispersion engineered silicon waveguides.

PubMed

Xu, Lin; Ophir, Noam; Menard, Michael; Lau, Ryan Kin Wah; Turner-Foster, Amy C; Foster, Mark A; Lipson, Michal; Gaeta, Alexander L; Bergman, Keren

2011-06-20

We experimentally demonstrate four-wave-mixing (FWM)-based continuous wavelength conversion of optical differential-phase-shift-keyed (DPSK) signals with large wavelength conversion ranges as well as simultaneous wavelength conversion of dual-wavelength channels with mixed modulation formats in 1.1-cm-long dispersion-engineered silicon waveguides. We first validate up to 100-nm wavelength conversion range for 10-Gb/s DPSK signals, showcasing the capability to perform phase-preserving operations at high bit rates in chip-scale devices over wide conversion ranges. We further validate the wavelength conversion of dual-wavelength channels modulated with 10-Gb/s packetized phase-shift-keyed (PSK) and amplitude-shift-keyed (ASK) signals; demonstrate simultaneous operation on multiple channels with mixed formats in chip-scale devices. For both configurations, we measure the spectral and temporal responses and evaluate the performances using bit-error-rate (BER) measurements.

Adapting and Validating a Scale to Measure Sexual Stigma among Lesbian, Bisexual and Queer Women

PubMed Central

Logie, Carmen H.; Earnshaw, Valerie

2015-01-01

Lesbian, bisexual and queer (LBQ) women experience pervasive sexual stigma that harms wellbeing. Stigma is a multi-dimensional construct and includes perceived stigma, awareness of negative attitudes towards one’s group, and enacted stigma, overt experiences of discrimination. Despite its complexity, sexual stigma research has generally explored singular forms of sexual stigma among LBQ women. The study objective was to develop a scale to assess perceived and enacted sexual stigma among LBQ women. We adapted a sexual stigma scale for use with LBQ women. The validation process involved 3 phases. First, we held a focus group where we engaged a purposively selected group of key informants in cognitive interviewing techniques to modify the survey items to enhance relevance to LBQ women. Second, we implemented an internet-based, cross-sectional survey with LBQ women (n=466) in Toronto, Canada. Third, we administered an internet-based survey at baseline and 6-week follow-up with LBQ women in Toronto (n=24) and Calgary (n=20). We conducted an exploratory factor analysis using principal components analysis and descriptive statistics to explore health and demographic correlates of the sexual stigma scale. Analyses yielded one scale with two factors: perceived and enacted sexual stigma. The total scale and subscales demonstrated adequate internal reliability (total scale alpha coefficient: 0.78; perceived sub-scale: 0.70; enacted sub-scale: 0.72), test-retest reliability, and construct validity. Perceived and enacted sexual stigma were associated with higher rates of depressive symptoms and lower self-esteem, social support, and self-rated health scores. Results suggest this sexual stigma scale adapted for LBQ women has good psychometric properties and addresses enacted and perceived stigma dimensions. The overwhelming majority of participants reported experiences of perceived sexual stigma. This underscores the importance of moving beyond a singular focus on discrimination to explore perceptions of social judgment, negative attitudes and social norms. PMID:25679391

[Research of urban eutrophic water repair by water/sediment biological bases].

PubMed

Zhou, Hui-Hua; Song, Xiao-Guang; Wu, Ge; Xie, Xin-Yuan

2013-10-01

A micro power turbine water aeration system with a water biological base and a sediment biological base was independently developed, aimed at urban water eutrophication. The results showed that the average removal rates of COD, NH+4 -N, TP by the water biological base were 82. 33% , 98. 00% and 54. 73% , respectively; The sediment reduction rate achieved by the sediment biological base could reach 20% within 5 days, and aeration in the overlying water could relieve the nutrient releasing caused by the degradation of organic matter; The effect of nutrient removal and organic matter reduction in sediment by the combined ecological restoration technology was perfect in pilot scale. The average removal rates of COD, NH+4 -N, TP were 52. 0%, 33. 6% and 23.4%, respectively, and the organic content in sediment was reduced from 38. 20% to 12.20% .

Large-scale deformed QRPA calculations of the gamma-ray strength function based on a Gogny force

NASA Astrophysics Data System (ADS)

Martini, M.; Goriely, S.; Hilaire, S.; Péru, S.; Minato, F.

2016-01-01

The dipole excitations of nuclei play an important role in nuclear astrophysics processes in connection with the photoabsorption and the radiative neutron capture that take place in stellar environment. We present here the results of a large-scale axially-symmetric deformed QRPA calculation of the γ-ray strength function based on the finite-range Gogny force. The newly determined γ-ray strength is compared with experimental photoabsorption data for spherical as well as deformed nuclei. Predictions of γ-ray strength functions and Maxwellian-averaged neutron capture rates for Sn isotopes are also discussed.

Dynamical complexity changes during two forms of meditation

NASA Astrophysics Data System (ADS)

Li, Jin; Hu, Jing; Zhang, Yinhong; Zhang, Xiaofeng

2011-06-01

Detection of dynamical complexity changes in natural and man-made systems has deep scientific and practical meaning. We use the base-scale entropy method to analyze dynamical complexity changes for heart rate variability (HRV) series during specific traditional forms of Chinese Chi and Kundalini Yoga meditation techniques in healthy young adults. The results show that dynamical complexity decreases in meditation states for two forms of meditation. Meanwhile, we detected changes in probability distribution of m-words during meditation and explained this changes using probability distribution of sine function. The base-scale entropy method may be used on a wider range of physiologic signals.

Chip-integrated optical power limiter based on an all-passive micro-ring resonator

NASA Astrophysics Data System (ADS)

Yan, Siqi; Dong, Jianji; Zheng, Aoling; Zhang, Xinliang

2014-10-01

Recent progress in silicon nanophotonics has dramatically advanced the possible realization of large-scale on-chip optical interconnects integration. Adopting photons as information carriers can break the performance bottleneck of electronic integrated circuit such as serious thermal losses and poor process rates. However, in integrated photonics circuits, few reported work can impose an upper limit of optical power therefore prevent the optical device from harm caused by high power. In this study, we experimentally demonstrate a feasible integrated scheme based on a single all-passive micro-ring resonator to realize the optical power limitation which has a similar function of current limiting circuit in electronics. Besides, we analyze the performance of optical power limiter at various signal bit rates. The results show that the proposed device can limit the signal power effectively at a bit rate up to 20 Gbit/s without deteriorating the signal. Meanwhile, this ultra-compact silicon device can be completely compatible with the electronic technology (typically complementary metal-oxide semiconductor technology), which may pave the way of very large scale integrated photonic circuits for all-optical information processors and artificial intelligence systems.

An Estimation of Turbulent Kinetic Energy and Energy Dissipation Rate Based on Atmospheric Boundary Layer Similarity Theory

NASA Technical Reports Server (NTRS)

Han, Jongil; Arya, S. Pal; Shaohua, Shen; Lin, Yuh-Lang; Proctor, Fred H. (Technical Monitor)

2000-01-01

Algorithms are developed to extract atmospheric boundary layer profiles for turbulence kinetic energy (TKE) and energy dissipation rate (EDR), with data from a meteorological tower as input. The profiles are based on similarity theory and scalings for the atmospheric boundary layer. The calculated profiles of EDR and TKE are required to match the observed values at 5 and 40 m. The algorithms are coded for operational use and yield plausible profiles over the diurnal variation of the atmospheric boundary layer.

A Nonlinear Dynamic Inversion Predictor-Based Model Reference Adaptive Controller for a Generic Transport Model

NASA Technical Reports Server (NTRS)

Campbell, Stefan F.; Kaneshige, John T.

2010-01-01

Presented here is a Predictor-Based Model Reference Adaptive Control (PMRAC) architecture for a generic transport aircraft. At its core, this architecture features a three-axis, non-linear, dynamic-inversion controller. Command inputs for this baseline controller are provided by pilot roll-rate, pitch-rate, and sideslip commands. This paper will first thoroughly present the baseline controller followed by a description of the PMRAC adaptive augmentation to this control system. Results are presented via a full-scale, nonlinear simulation of NASA s Generic Transport Model (GTM).

Spatiotemporal analysis of land use and land cover change in the Brazilian Amazon

PubMed Central

Li, Guiying; Moran, Emilio; Hetrick, Scott

2013-01-01

This paper provides a comparative analysis of land use and land cover (LULC) changes among three study areas with different biophysical environments in the Brazilian Amazon at multiple scales, from per-pixel, polygon, census sector, to study area. Landsat images acquired in the years of 1990/1991, 1999/2000, and 2008/2010 were used to examine LULC change trajectories with the post-classification comparison approach. A classification system composed of six classes – forest, savanna, other-vegetation (secondary succession and plantations), agro-pasture, impervious surface, and water, was designed for this study. A hierarchical-based classification method was used to classify Landsat images into thematic maps. This research shows different spatiotemporal change patterns, composition and rates among the three study areas and indicates the importance of analyzing LULC change at multiple scales. The LULC change analysis over time for entire study areas provides an overall picture of change trends, but detailed change trajectories and their spatial distributions can be better examined at a per-pixel scale. The LULC change at the polygon scale provides the information of the changes in patch sizes over time, while the LULC change at census sector scale gives new insights on how human-induced activities (e.g., urban expansion, roads, and land use history) affect LULC change patterns and rates. This research indicates the necessity to implement change detection at multiple scales for better understanding the mechanisms of LULC change patterns and rates. PMID:24127130

The development and validation of the core competencies scale (CCS) for the college and university students.

PubMed

Ruan, Bin; Mok, Magdalena Mo Ching; Edginton, Christopher R; Chin, Ming Kai

2012-01-01

This article describes the development and validation of the Core Competencies Scale (CCS) using Bok's (2006) competency framework for undergraduate education. The framework included: communication, critical thinking, character development, citizenship, diversity, global understanding, widening of interest, and career and vocational development. The sample comprised 70 college and university students. Results of analysis using Rasch rating scale modelling showed that there was strong empirical evidence on the validity of the measures in contents, structure, interpretation, generalizability, and response options of the CCS scale. The implication of having developed Rasch-based valid and dependable measures in this study for gauging the value added of college and university education to their students is that the feedback generated from CCS will enable evidence-based decision and policy making to be implemented and strategized. Further, program effectiveness can be measured and thus accountability on the achievement of the program objectives.

Uncertainty analysis on simple mass balance model to calculate critical loads for soil acidity.

PubMed

Li, Harbin; McNulty, Steven G

2007-10-01

Simple mass balance equations (SMBE) of critical acid loads (CAL) in forest soil were developed to assess potential risks of air pollutants to ecosystems. However, to apply SMBE reliably at large scales, SMBE must be tested for adequacy and uncertainty. Our goal was to provide a detailed analysis of uncertainty in SMBE so that sound strategies for scaling up CAL estimates to the national scale could be developed. Specifically, we wanted to quantify CAL uncertainty under natural variability in 17 model parameters, and determine their relative contributions in predicting CAL. Results indicated that uncertainty in CAL came primarily from components of base cation weathering (BC(w); 49%) and acid neutralizing capacity (46%), whereas the most critical parameters were BC(w) base rate (62%), soil depth (20%), and soil temperature (11%). Thus, improvements in estimates of these factors are crucial to reducing uncertainty and successfully scaling up SMBE for national assessments of CAL.

Study of the relationship between the aerobic capacity (VO2 max) and the rating of perceived exertion based on the measurement of heart beat in the metal industries Esfahan

PubMed Central

Habibi, Ehsanollah; Dehghan, Habibollah; Moghiseh, Mohammad; Hasanzadeh, Akbar

2014-01-01

Background and Objective: To establish a balance between work (physical exercise) and human beings, the aerobic capacity (VO2 max) could be used as a measure. Additionally, the subjective and physiological assessment could be applied as one of the methods for assessing physical exercise. The most commonly used tools for the assessment of fatigue during physical exercise include the Borg scale Rating of perceived Exertion (RPE) in relation to subjective symptoms and heart rate (HR) in relation to physiological symptoms. The study is aimed to investigate the relationship between the aerobic capacity and the RPE based on the measurement of heat rate (HR) of workers from the Metal Industries of Isfahan. Materials and Methods: The subjects were 200 male workers from metal components manufacturers in Isfahan selected by using random sampling based on statistic method. The subjects were examined by using ergometer in accordance with A strand 6 minutes cycle test protocol. Furthermore, the subjects were asked to rate their status based on the Borg rating scale at the end of each minute. Additionally, their heat rates were monitored and recorded automatically at the end of each minutes. Results: Statistical analysis showed that there was a significant relationship between the RPE and the aerobic capacity (VO2 max) (r = –0.904, P < 0.05). The results illustrated that there was a stronger correlation between HR and VO2 max (r = 0.991, P < 0.001). The regression analysis of the quadratic equation also indicated that there was also a significant relationship between the VO2 max and HR. Conclusions: The results indicated that there was a strong relationship between the RPE and VO2 max, as well as a greater correlation between HR and VO2 max. Therefore, the HR could be used as a Prediction measure to estimate VO2 max. PMID:25077148

The calibration analysis of soil infiltration formula in farmland scale

NASA Astrophysics Data System (ADS)

Qian, Tao; Han, Na Na; Chang, Shuan Ling

2018-06-01

Soil infiltration characteristic is an important basis of farmland scale parameter estimation. Based on 12 groups of double-loop infiltration tests conducted in the test field of tianjin agricultural university west campus. Based on the calibration theory and the combination of statistics, the calibration analysis of phillips formula was carried out and the spatial variation characteristics of the calibration factor were analyzed. Results show that in study area based on the soil stability infiltration rate A calculate calibration factor αA calibration effect is best, that is suitable for the area formula of calibration infiltration and αA variation coefficient is 0.3234, with A certain degree of spatial variability.

Measuring Cognitive Load with Subjective Rating Scales during Problem Solving: Differences between Immediate and Delayed Ratings

ERIC Educational Resources Information Center

Schmeck, Annett; Opfermann, Maria; van Gog, Tamara; Paas, Fred; Leutner, Detlev

2015-01-01

Subjective cognitive load (CL) rating scales are widely used in educational research. However, there are still some open questions regarding the point of time at which such scales should be applied. Whereas some studies apply rating scales directly after each step or task and use an average of these ratings, others assess CL only once after the…

Psychometric Properties of ADHD Rating Scales among Children with Mental Retardation I: Reliability

ERIC Educational Resources Information Center

Miller, Michael L.; Fee, Virginia E.; Netterville, Amanda K.

2004-01-01

The reliability of Attention-Deficit/Hyperactivity Disorder (ADHD) rating scales in children with mental retardation was assessed. Parents, teachers, and teaching assistants completed ADHD rating scales on 48 children aged 5-12 diagnosed with mental retardation. Measures included the Child Behavior Checklist (CBCL), Conners Rating Scales, the…

Exploring stability of entropy analysis for signal with different trends

NASA Astrophysics Data System (ADS)

Zhang, Yin; Li, Jin; Wang, Jun

2017-03-01

Considering the effects of environment disturbances and instrument systems, the actual detecting signals always are carrying different trends, which result in that it is difficult to accurately catch signals complexity. So choosing steady and effective analysis methods is very important. In this paper, we applied entropy measures-the base-scale entropy and approximate entropy to analyze signal complexity, and studied the effect of trends on the ideal signal and the heart rate variability (HRV) signals, that is, linear, periodic, and power-law trends which are likely to occur in actual signals. The results show that approximate entropy is unsteady when we embed different trends into the signals, so it is not suitable to analyze signal with trends. However, the base-scale entropy has preferable stability and accuracy for signal with different trends. So the base-scale entropy is an effective method to analyze the actual signals.

The minimum or natural rate of flow and droplet size ejected by Taylor cone-jets: physical symmetries and scaling laws

NASA Astrophysics Data System (ADS)

Gañán-Calvo, A. M.; Rebollo-Muñoz, N.; Montanero, J. M.

2013-03-01

We aim to establish the scaling laws for both the minimum rate of flow attainable in the steady cone-jet mode of electrospray, and the size of the resulting droplets in that limit. Use is made of a small body of literature on Taylor cone-jets reporting precise measurements of the transported electric current and droplet size as a function of the liquid properties and flow rate. The projection of the data onto an appropriate non-dimensional parameter space maps a region bounded by the minimum rate of flow attainable in the steady state. To explain these experimental results, we propose a theoretical model based on the generalized concept of physical symmetry, stemming from the system time invariance (steadiness). A group of symmetries rising at the cone-to-jet geometrical transition determines the scaling for the minimum flow rate and related variables. If the flow rate is decreased below that minimum value, those symmetries break down, which leads to dripping. We find that the system exhibits two instability mechanisms depending on the nature of the forces arising against the flow: one dominated by viscosity and the other by the liquid polarity. In the former case, full charge relaxation is guaranteed down to the minimum flow rate, while in the latter the instability condition becomes equivalent to the symmetry breakdown by charge relaxation or separation. When cone-jets are formed without artificially imposing a flow rate, a microjet is issued quasi-steadily. The flow rate naturally ejected this way coincides with the minimum flow rate studied here. This natural flow rate determines the minimum droplet size that can be steadily produced by any electrohydrodynamic means for a given set of liquid properties.

Oppositional Defiant Disorder: prevalence based on parent and teacher ratings of Malaysian primary school children.

PubMed

Gomez, Rapson; Hafetz, Nina; Gomez, Rashika Miranjani

2013-08-01

This study examined the prevalence rate of Oppositional Defiant Disorder (ODD) in Malaysian primary school children. In all 934 Malaysian parents and teachers completed ratings of their children using a scale comprising DSM-IV-TR ODD symptoms. Results showed rates of 3.10%, 3.85%, 7.49% and 0.64% for parent, teacher, parent or teacher ("or-rule"), and parent and teacher ("and-rule") ratings, respectively. When the functional impairment criterion was not considered, the rate reported by parents was higher at 13.28%. The theoretical, diagnostic and cultural implications of the findings are discussed. Copyright © 2013 Elsevier B.V. All rights reserved.

Predictors of performance-based measures of instrumental activities of daily living in nondemented patients with Parkinson's disease.

PubMed

Pirogovsky, Eva; Martinez-Hannon, Mercedes; Schiehser, Dawn M; Lessig, Stephanie L; Song, David D; Litvan, Irene; Filoteo, J Vincent

2013-01-01

Few studies have examined instrumental activities of daily living (iADLs) in nondemented Parkinson's disease (PD), and the majority of these studies have used report-based measures, which can have limited validity. The present study had two main goals: (a) to examine the performance of nondemented PD patients on two performance-based measures of iADLs, which are considered more objective functional measures, and (b) to examine the cognitive, motor, and psychiatric correlates of iADL impairment in PD. Ninety-eight nondemented PD patients and 47 healthy older adults were administered performance-based measures that assess the ability to manage medications (Medication Management Ability Assessment) and finances (University of California, San Diego, UCSD, Performance-based Skills Assessment), the Mattis Dementia Rating Scale to assess global cognitive functioning, the Unified Parkinson's Disease Rating Scale Part III to assess motor symptom severity, and the Geriatric Depression Scale to assess depressive symptoms. Nondemented PD patients demonstrated significantly impaired scores relative to the healthy comparison group on the performance-based measure of financial management, but there were no significant group differences in medication management. Global cognitive functioning, motor severity, and depressive symptoms did not correlate with scores on either of the functional measures, except for a small correlation between depressive symptoms and financial management. The two performance-based measures of iADL functioning did not correlate with one another. These findings suggest that medication and financial management may not be predicted based on global cognitive functioning and that iADLs may not be represented by a single construct. Furthermore, these findings suggest the potential need for a multidimensional approach to assessing iADLs.

Reconciling theories for metabolic scaling.

PubMed

Maino, James L; Kearney, Michael R; Nisbet, Roger M; Kooijman, Sebastiaan A L M

2014-01-01

Metabolic theory specifies constraints on the metabolic organisation of individual organisms. These constraints have important implications for biological processes ranging from the scale of molecules all the way to the level of populations, communities and ecosystems, with their application to the latter emerging as the field of metabolic ecology. While ecologists continue to use individual metabolism to identify constraints in ecological processes, the topic of metabolic scaling remains controversial. Much of the current interest and controversy in metabolic theory relates to recent ideas about the role of supply networks in constraining energy supply to cells. We show that an alternative explanation for physicochemical constraints on individual metabolism, as formalised by dynamic energy budget (DEB) theory, can contribute to the theoretical underpinning of metabolic ecology, while increasing coherence between intra- and interspecific scaling relationships. In particular, we emphasise how the DEB theory considers constraints on the storage and use of assimilated nutrients and derive an equation for the scaling of metabolic rate for adult heterotrophs without relying on optimisation arguments or implying cellular nutrient supply limitation. Using realistic data on growth and reproduction from the literature, we parameterise the curve for respiration and compare the a priori prediction against a mammalian data set for respiration. Because the DEB theory mechanism for metabolic scaling is based on the universal process of acquiring and using pools of stored metabolites (a basal feature of life), it applies to all organisms irrespective of the nature of metabolic transport to cells. Although the DEB mechanism does not necessarily contradict insight from transport-based models, the mechanism offers an explanation for differences between the intra- and interspecific scaling of biological rates with mass, suggesting novel tests of the respective hypotheses. © 2013 The Authors. Journal of Animal Ecology © 2013 British Ecological Society.

Satisfaction with web-based training in an integrated healthcare delivery network: do age, education, computer skills and attitudes matter?

PubMed Central

Atreja, Ashish; Mehta, Neil B; Jain, Anil K; Harris, CM; Ishwaran, Hemant; Avital, Michel; Fishleder, Andrew J

2008-01-01

Background Healthcare institutions spend enormous time and effort to train their workforce. Web-based training can potentially streamline this process. However the deployment of web-based training in a large-scale setting with a diverse healthcare workforce has not been evaluated. The aim of this study was to evaluate the satisfaction of healthcare professionals with web-based training and to determine the predictors of such satisfaction including age, education status and computer proficiency. Methods Observational, cross-sectional survey of healthcare professionals from six hospital systems in an integrated delivery network. We measured overall satisfaction to web-based training and response to survey items measuring Website Usability, Course Usefulness, Instructional Design Effectiveness, Computer Proficiency and Self-learning Attitude. Results A total of 17,891 healthcare professionals completed the web-based training on HIPAA Privacy Rule; and of these, 13,537 completed the survey (response rate 75.6%). Overall course satisfaction was good (median, 4; scale, 1 to 5) with more than 75% of the respondents satisfied with the training (rating 4 or 5) and 65% preferring web-based training over traditional instructor-led training (rating 4 or 5). Multivariable ordinal regression revealed 3 key predictors of satisfaction with web-based training: Instructional Design Effectiveness, Website Usability and Course Usefulness. Demographic predictors such as gender, age and education did not have an effect on satisfaction. Conclusion The study shows that web-based training when tailored to learners' background, is perceived as a satisfactory mode of learning by an interdisciplinary group of healthcare professionals, irrespective of age, education level or prior computer experience. Future studies should aim to measure the long-term outcomes of web-based training. PMID:18922178