Abubackar, Haris Nalakath; Veiga, María C; Kennes, Christian
2015-06-01
Fermentation of CO or syngas offers an attractive route to produce bioethanol. However, during the bioconversion, one of the challenges to overcome is to reduce the production of acetic acid in order to minimize recovery costs. Different experiments were done with Clostridium autoethanogenum. With the addition of 0.75 μM tungsten, ethanol production from carbon monoxide increased by about 128% compared to the control, without such addition, in batch mode. In bioreactors with continuous carbon monoxide supply, the maximum biomass concentration reached at pH 6.0 was 109% higher than the maximum achieved at pH 4.75 but, interestingly, at pH 4.75, no acetic acid was produced and the ethanol titer reached a maximum of 867 mg/L with minor amounts of 2,3-butanediol (46 mg/L). At the higher pH studied (pH 6.0) in the continuous gas-fed bioreactor, almost equal amounts of ethanol and acetic acid were formed, reaching 907.72 mg/L and 910.69 mg/L respectively. Copyright © 2015 Elsevier Ltd. All rights reserved.
Han, Peng-de; Zhang, Le; Huang, Xiao-gu; Wang, Li-xi; Zhang, Qi-tu
2010-11-01
Y2O3 powders doped with rare-earth ions were synthesized by sol-gel combustion synthesis. Effects of different calcinating temperatures, Er+ doping concentration and Yb3+ doping concentration were investigated. It was shown that the single well crystallized Y2O3 powders could be obtained at 800 degrees C; as the calcinating temperature increased, the crystallinity and upconversion luminescence intensity were higher; the particle size was uniform around 1 microm at 900 degrees C; when Er3+ doping concentration was 1 mol%, the green upconversion luminescence intensity reached the maximum, but for red upconversion luminescence, when Er3+ doping concentration was 4 mol%, its luminescence intensity reached the maximum; as the ratio of Yb3+ to Er3+ was 4:1, the green emission intensity reached the maximum, while the red emission intensity was always increasing as Yb3+ doping concentration increased.
Zheljazkov, Valtcho D; Astatkie, Tess; Jeliazkova, Ekaterina A; Schlegel, Vicki
2012-01-01
The objective of this study was to evaluate the effect of 15 distillation times (DT), ranging from 1.25 to 960 min, on oil yield, essential oil profiles, and antioxidant capacity of male J. scopulorum trees. Essential oil yields were 0.07% at 1.25 min DT and reached a maximum of 1.48% at 840 min DT. The concentrations of alpha-thujene (1.76-2.75%), alpha-pinene (2.9-8.7%), sabinene (45-74.7%), myrcene (2.4-3.4%), and para-cymene (0.8-3.1%) were highest at the shortest DT (1.5 to 5 min) and decreased with increasing DT. Cis-sabinene hydrate (0.5-0.97%) and linalool plus trans-sabinene (0.56-1.6%) reached maximum levels at 40 min DT. Maximum concentrations of limonene (2.3-2.8%) and pregeijerene-B (0.06-1.4%) were obtained at 360-480 min DT, and 4-terpinenol (0.7-5.7%) at 480 min DT. Alpha-terpinene (0.16-2.9%), gamma-terpinene (0.3-4.9%) and terpinolene (0.3-1.4%) reached maximum at 720 min DT. The concentrations of delta-cadinene (0.06-1.65%), elemol (0-6.0%), and 8-alpha-acetoxyelemol (0-4.4%) reached maximum at 840 min DT. The yield of the essential oil constituents increased with increasing DT. Only linalool/transsabinene hydrate reached a maximum yield at 360 min DT. Maximum yields of the following constituents were obtained at 720 min DT: alpha-thujene, alpha-pinene, camphene, sabinene, myrcene, alpha-terpinene, para-cimene, limonene, gamma-terpinene, terpinolene, and 4-terpinenol. At 840 min DT, cis-sabinene hydrate, prejeijerene-B, gamma muurolene, delta-cadinene, reached maximum. At 960 min DT, maximum yields of beta-pinene, elemol, alphaeudesmol/betaeudesmol, 8-alpha-acetoxyelemol were reached. These changes were adequately modeled by either the Michaelis-Menten or the Power (Convex) nonlinear regression models. Oils from the 480 min DT showed higher antioxidant activity compared to samples collected at 40, 160, or 960 min DT. These results show the potential for obtaining essential oils with various compositions and antioxidant capacity from male J. scopulorum by varying DT. This study can be used as a reference paper for comparing results of reports where different lengths of the DT were used.
Choi, Jeongdong; Ahn, Youngho
2015-05-01
Microbial fuel cells (MFCs) treating the food waste leachate produced from biohydrogen fermentation were examined to enhance power generation and energy recovery. In batch mode, the maximum voltage production was 0.56 V and the power density reached 1540 mW/m(2). The maximum Coulombic efficiency (CEmax) and energy efficiency (EE) in the batch mode were calculated to be 88.8% and 18.8%, respectively. When the organic loading rate in sequencing batch mode varied from 0.75 to 6.2 g COD/L-d (under CEmax), the maximum power density reached 769.2 mW/m(2) in OLR of 3.1 g COD/L-d, whereas higher energy recovery (CE=52.6%, 0.346 Wh/g CODrem) was achieved at 1.51 g COD/L-d. The results demonstrate that readily biodegradable substrates in biohydrogen fermentation can be effectively used for the enhanced bioelectricity harvesting of MFCs and a MFC coupled with biohydrogen fermentation is of great benefit on higher electricity generation and energy efficiency. Copyright © 2015 Elsevier Ltd. All rights reserved.
Effect of σ2 on All Aspects of Failure in Rocks from Granite to Sandstone
NASA Astrophysics Data System (ADS)
Haimson, B. C.; Ma, X.
2014-12-01
We have studied the effect of σ2 on failure characteristics of two crystalline and three clastic rocks subjected to true triaxial stresses. Common to all rocks tested is the rise in both strain localization onset and σ1 at failure (σ1,peak) for a given σ3, as σ2 is elevated beyond its base level (σ2 = σ3). σ1,peak reaches a maximum at some level of σ2, beyond which it gradually declines, approaching its base magnitude when σ2 nears its own maximum. Failure-plane angle with respect to σ1 for a given σ3 also increases with σ2, at least until the maximum σ1,peak is reached. Westerly granite (Haimson and Chang, IJRMMS, 2000) and KTB amphibolite (Chang and Haimson, JGR, 2000), exhibited a dramatic σ2 effect: at low σ3 (20-30 MPa), higher σ2 lifted σ1,peak by up to 50% over its base level. At high σ3, the increase in σ1,peak was reduced, but even at σ3 = 100 MPa, maximum σ1,peak in both rocks was over 20% higher than its base level. Failure mode remained brittle throughout the stress range tested, but the onset of dilatancy rose with σ2, as did the failure-plane (shear-band) angle (by up to 20°). A gentler effect of σ2 on σ1, peak and failure-plane angle was observed in the clastics, and that effect subsided as porosity increased. In low porosity (φ = 7%) TCDP siltstone (Oku, et al, GRL, 2007), the maximum σ1,peak at σ3 = 25 MPa was about 30% larger than at σ2 = σ3 level, and only 12.5% larger at σ3 = 100 MPa. Failure mode stayed brittle throughout, but shear-band angle increase with σ2 was limited to about 10°, irrespective of σ3 level. An even smaller σ2 effect was observed in Coconino sandstone (φ = 17%) (Ma, PhD thesis, 2014). σ1,peak reached a maximum of about 10% higher than at σ2 = σ3 level; failure-plane angle rise with σ2 was less than 10°. The weakest σ2 effect was found in the high porosity (φ= 25%) Bentheim sandstone (Ma, PhD thesis, 2014). Here σ1, peak reached a maximum of well under 10% higher than its base magnitude, regardless of σ3 level; average failure-plane angle rise with σ2 was below 10°. Failure at σ3 = 150 MPa was along a compaction band(s) normal to σ1, regardless of σ2. Both Coconino and Bentheim underwent dilatant failure at low σ3, shifting to compactive failure at high σ3 levels. But σ2 also affected the failure mode: compactive failure at σ2 = σ3 gradually reverted to a dilatant mode as σ2 was raised.
Lee, Songil; Kyung, Gyouhyung; Lee, Jungyong; Moon, Seung Ki; Park, Kyoung Jong
2016-11-01
Recently, some smartphones have introduced index finger interaction functions on the rear surface. The current study investigated the effects of task type, phone width, and hand length on grasp, index finger reach zone, discomfort, and muscle activation during such interaction. We considered five interaction tasks (neutral, comfortable, maximum, vertical, and horizontal strokes), two device widths (60 and 90 mm) and three hand lengths. Horizontal (vertical) strokes deviated from the horizontal axis in the range from -10.8° to -13.5° (81.6-88.4°). Maximum strokes appeared to be excessive as these caused 43.8% greater discomfort than did neutral strokes. The 90-mm width also appeared to be excessive as it resulted in 12.3% increased discomfort relative to the 60-mm width. The small-hand group reported 11.9-18.2% higher discomfort ratings, and the percent maximum voluntary exertion of their flexor digitorum superficialis muscle, pertaining to index finger flexion, was also 6.4% higher. These findings should be considered to make smartphone rear interaction more comfortable. Practitioner Summary: Among neutral, comfortable, maximum, horizontal, and vertical index finger strokes on smartphone rear surfaces, maximum vs. neutral strokes caused 43.8% greater discomfort. Horizontal (vertical) strokes deviated from the horizontal (vertical) axis. Discomfort increased by 12.3% with 90-mm- vs. 60-mm-wide devices. Rear interaction regions of five commercialised smartphones should be lowered 20 to 30 mm for more comfortable rear interaction.
NASA Astrophysics Data System (ADS)
Li, lingxue
2017-08-01
The paper designs a new wind-water cooling and heating water conditioner system, connects cooling tower with heat recovery device, which uses cooling water to completely remove the heat that does not need heat recollection, in order to ensure that the system can work efficiently with higher performance coefficient. After the test actual engineering operation, the system’s maximum cooling coefficient of performance can reach 3.5. Its maximum comprehensive coefficient of performance can reach 6.5. After the analysis of its economic and environmental, we conclude that the new system can save 89822 kw per year. It reflects energy-saving and environmental benefits of the cold and hot water air conditioning system.
The mixing effects for real gases and their mixtures
NASA Astrophysics Data System (ADS)
Gong, M. Q.; Luo, E. C.; Wu, J. F.
2004-10-01
The definitions of the adiabatic and isothermal mixing effects in the mixing processes of real gases were presented in this paper. Eight substances with boiling-point temperatures from cryogenic temperature to the ambient temperature were selected from the interest of low temperature refrigeration to study their binary and multicomponent mixing effects. Detailed analyses were made on the parameters of the mixing process to know their influences on mixing effects. Those parameters include the temperatures, pressures, and mole fraction ratios of pure substances before mixing. The results show that the maximum temperature variation occurs at the saturation state of each component in the mixing process. Those components with higher boiling-point temperatures have higher isothermal mixing effects. The maximum temperature variation which is defined as the adiabatic mixing effect can even reach up to 50 K, and the isothermal mixing effect can reach about 20 kJ/mol. The possible applications of the mixing cooling effect in both open cycle and closed cycle refrigeration systems were also discussed.
Hintze-Podufal, Ch
1970-12-01
During the larval development ofCerura vinula L. consecutive instars are of increasing length. The time requirement for each instar is temperature dependent. They are shorter at higher and longer at lower temperatures.The data of the first larval instars suggest that the leaves were digested at a much higher rate at 18° C than at 25°C and 30° C. The data of the 5. instar do not show this difference as clearly. During the 5. instar maximum of defeacation was reached by an s-shaped curve. This curve may be divided into two different phases: During the first phase there is a steady increase. During the second phase the rise decreases steadily until the maximum of defeacation is reached. The first phase may be shortened by higher temperatures, while the second phase may not be altered. Short cyclic variations with irregular periodic length of 8-16 hours seeme to be superimposed on this s-shaped curve. There is evidence that the position of their maxima and minima are correlated with the day-night cycle. This effect is described quantitatively by the tendency-curve.
NASA Astrophysics Data System (ADS)
Govatski, J. A.; da Luz, M. G. E.; Koehler, M.
2015-01-01
We study the geminated pair dissociation probability φ as function of applied electric field and temperature in energetically disordered nD media. Regardless nD, for certain parameters regions φ versus the disorder degree (σ) displays anomalous minimum (maximum) at low (moderate) fields. This behavior is compatible with a transport energy which reaches a maximum and then decreases to negative values as σ increases. Our results explain the temperature dependence of the persistent photoconductivity in C60 single crystals going through order-disorder transitions. They also indicate how an energetic disorder spatial variation may contribute to higher exciton dissociation in multicomponent donor/acceptor systems.
NASA Astrophysics Data System (ADS)
Ma, Xinyu; Liu, Lizhu; Zhang, Xiaorui; He, Hongju
2018-06-01
A series of sandwich structure PI films were prepared by different imidization process, with pure PI film as the interlayer and PI/Al2O3 composite films as outer layers. The imidization rate of the film with different cured processes was calculated by characterizing by infrared spectrum (FT-IR), and the morphology of interlayer interface with different imidization rates by scanning electron microscope (SEM). When the imidization conditions of the first and second films were 260 °C/120 min, the composite films displayed better interface structure and higher imidization rate (ID) than others. Moreover, results also showed that the conduction current of three-layer composite film steadily improved with increased ID and temperature, and was higher than that of the pure film. At the temperature of 30 °C, the electrical aging threshold at different ID was obtained. When the ID reached the maximum value of 78.9%, the electrical aging threshold reached the maximum 41.69 kV/mm.
Jian, Ming; He, Hua; Ma, Changsong; Wu, Yan; Yang, Hao
2017-05-17
This article studies the price competition and cooperation in a duopoly that is subjected to carbon emissions cap. The study assumes that in a departure from the classical Bertrand game, there is still a market for both firms' goods regardless of the product price, even though production capacity is limited by carbon emissions regulation. Through the decentralized decision making of both firms under perfect information, the results are unstable. The firm with the lower maximum production capacity under carbon emissions regulation and the firm with the higher maximum production capacity both seek market price cooperation. By designing an internal carbon credits trading mechanism, we can ensure that the production capacity of the firm with the higher maximum production capacity under carbon emissions regulation reaches price equilibrium. Also, the negotiation power of the duopoly would affect the price equilibrium.
NASA Astrophysics Data System (ADS)
Garner, Grace; Malcolm, Iain A.; Sadler, Jonathan P.; Hannah, David M.
2017-10-01
A simulation experiment was used to understand the importance of riparian vegetation density, channel orientation and flow velocity for stream energy budgets and river temperature dynamics. Water temperature and meteorological observations were obtained in addition to hemispherical photographs along a ∼1 km reach of the Girnock Burn, a tributary of the Aberdeenshire Dee, Scotland. Data from nine hemispherical images (representing different uniform canopy density scenarios) were used to parameterise a deterministic net radiation model and simulate radiative fluxes. For each vegetation scenario, the effects of eight channel orientations were investigated by changing the position of north at 45° intervals in each hemispheric image. Simulated radiative fluxes and observed turbulent fluxes drove a high-resolution water temperature model of the reach. Simulations were performed under low and high water velocity scenarios. Both velocity scenarios yielded decreases in mean (≥1.6 °C) and maximum (≥3.0 °C) temperature as canopy density increased. Slow-flowing water resided longer within the reach, which enhanced heat accumulation and dissipation, and drove higher maximum and lower minimum temperatures. Intermediate levels of shade produced highly variable energy flux and water temperature dynamics depending on the channel orientation and thus the time of day when the channel was shaded. We demonstrate that in many reaches relatively sparse but strategically located vegetation could produce substantial reductions in maximum temperature and suggest that these criteria are used to inform future river management.
Parametric Imaging Of Digital Subtraction Angiography Studies For Renal Transplant Evaluation
NASA Astrophysics Data System (ADS)
Gallagher, Joe H.; Meaney, Thomas F.; Flechner, Stuart M.; Novick, Andrew C.; Buonocore, Edward
1981-11-01
A noninvasive method for diagnosing acute tubular necrosis and rejection would be an important tool for the management of renal transplant patients. From a sequence of digital subtraction angiographic images acquired after an intravenous injection of radiographic contrast material, the parametric images of the maximum contrast, the time when the maximum contrast is reached, and two times the time at which one half of the maximum contrast is reached are computed. The parametric images of the time when the maximum is reached clearly distinguish normal from abnormal renal function. However, it is the parametric image of two times the time when one half of the maximum is reached which provides some assistance in differentiating acute tubular necrosis from rejection.
NASA Technical Reports Server (NTRS)
Ni, Xiang; Liu, Chuntao; Zhang, Qinghong; Cecil, Daniel J.
2016-01-01
A 16-yr record of hail reports over the southeast US and from weather stations in China are collocated with Precipitation Features (PF) derived from the Tropical Rainfall Measurement Mission (TRMM) radar and passive microwave observations. While U.S. hail reports are dominated by cases with hail size greater than 19 mm, hail reports in China mostly include diameters of 1-10 nm and mostly occur over the Tibetan Plateau. The fraction of PFs collocated with hail reports (hail PFs) reaches 3% in the plains of the U.S. In China, the fraction is higher in high elevation regions than low elevation regions. Hail PFs in the U.S. show lower brightness temperatures, higher lightning flash rates, stronger maximum reflectivity, and higher echo tops than those in China, consistent with the larger hail diameters in the U.S. reports. The average near surface maximum reflectivity of hail PFs at higher elevations (greater than or equal to 2000 m) in China is about 5 dB smaller than those at low elevations. Larger hail is reported with PFs having stronger maximum reflectivity above 6 km, though the median of maximum reflectivity values at levels below 5 km is close among the storms with large and small hail sizes.
[Effect of UV Light Radiation on the Coagulation of Chlorella and Its Mechanism].
Wang, Wen-dong; Zhang, Ke; Xu, Hong-bin; Liu, Guo-qi
2016-01-15
Considering algae were difficult to be effectively removed in conventional water treatment process, UV radiation was used to enhance the coagulation of algae in this study. The results showed that with the increase of radiation time, the removal rates of both algae and turbidity experienced a decrease after an increase, and reached their maximum values at 50 min. When the dosage of PAC was 5 mg x L(-1), the removal rates of algae and turbidity of the radiated sample were 20.1% and 18% higher than the blank sample, respectively. When pH ranged from 6 to 9, the coagulation efficiency varied little. At pH 8 and with a radiation time of 50 min, the removal rates of algae and turbidity reached 93.5% and 90.6%, respectively. Meanwhile, the Zeta potential reached the maximum, and the algae generated extracellular organic matter, which favored the subsequent coagulation. After radiated for 60 min, the algal cells was destroyed, leading to a release of intracellular organic matter into the solution. Accordingly, the Zeta potential decreased, which had a negative effect on the subsequent coagulation process.
Disc piezoelectric ceramic transformers.
Erhart, Jirií; Půlpán, Petr; Doleček, Roman; Psota, Pavel; Lédl, Vít
2013-08-01
In this contribution, we present our study on disc-shaped and homogeneously poled piezoelectric ceramic transformers working in planar-extensional vibration modes. Transformers are designed with electrodes divided into wedge, axisymmetrical ring-dot, moonie, smile, or yin-yang segments. Transformation ratio, efficiency, and input and output impedances were measured for low-power signals. Transformer efficiency and transformation ratio were measured as a function of frequency and impedance load in the secondary circuit. Optimum impedance for the maximum efficiency has been found. Maximum efficiency and no-load transformation ratio can reach almost 100% and 52 for the fundamental resonance of ring-dot transformers and 98% and 67 for the second resonance of 2-segment wedge transformers. Maximum efficiency was reached at optimum impedance, which is in the range from 500 Ω to 10 kΩ, depending on the electrode pattern and size. Fundamental vibration mode and its overtones were further studied using frequency-modulated digital holographic interferometry and by the finite element method. Complementary information has been obtained by the infrared camera visualization of surface temperature profiles at higher driving power.
Factors associated with higher oxytocin requirements in labor.
Frey, Heather A; Tuuli, Methodius G; England, Sarah K; Roehl, Kimberly A; Odibo, Anthony O; Macones, George A; Cahill, Alison G
2015-09-01
To identify clinical characteristics associated with high maximum oxytocin doses in women who achieve complete cervical dilation. A retrospective nested case-control study was performed within a cohort of all term women at a single center between 2004 and 2008 who reached the second stage of labor. Cases were defined as women who had a maximum oxytocin dose during labor >20 mu/min, while women in the control group had a maximum oxytocin dose during labor of ≤20 mu/min. Exclusion criteria included no oxytocin administration during labor, multiple gestations, major fetal anomalies, nonvertex presentation, and prior cesarean delivery. Multiple maternal, fetal, and labor factors were evaluated with univariable analysis and multivariable logistic regression. Maximum oxytocin doses >20 mu/min were administered to 108 women (3.6%), while 2864 women received doses ≤20 mu/min. Factors associated with higher maximum oxytocin dose after adjusting for relevant confounders included maternal diabetes, birthweight >4000 g, intrapartum fever, administration of magnesium, and induction of labor. Few women who achieve complete cervical dilation require high doses of oxytocin. We identified maternal, fetal and labor factors that characterize this group of parturients.
Nazrullaeva, M F; Alekseev, A N
1991-01-01
The efficacy of minihygrometers in the study of bed microclimate (a shelter of dust ticks) has been assessed. Maximum difference between minihygrometer and August's psychrometer parameters reaches 0.5%. In all shelters of ticks humidity at night was higher than in the premises, which demonstrates the efficacy of the method used.
Design and optimization of a modal- independent linear ultrasonic motor.
Zhou, Shengli; Yao, Zhiyuan
2014-03-01
To simplify the design of the linear ultrasonic motor (LUSM) and improve its output performance, a method of modal decoupling for LUSMs is proposed in this paper. The specific embodiment of this method is decoupling of the traditional LUSM stator's complex vibration into two simple vibrations, with each vibration implemented by one vibrator. Because the two vibrators are designed independently, their frequencies can be tuned independently and frequency consistency is easy to achieve. Thus, the method can simplify the design of the LUSM. Based on this method, a prototype modal- independent LUSM is designed and fabricated. The motor reaches its maximum thrust force of 47 N, maximum unloaded speed of 0.43 m/s, and maximum power of 7.85 W at applied voltage of 200 Vpp. The motor's structure is then optimized by controlling the difference between the two vibrators' resonance frequencies to reach larger output speed, thrust, and power. The optimized results show that when the frequency difference is 73 Hz, the output force, speed, and power reach their maximum values. At the input voltage of 200 Vpp, the motor reaches its maximum thrust force of 64.2 N, maximum unloaded speed of 0.76 m/s, maximum power of 17.4 W, maximum thrust-weight ratio of 23.7, and maximum efficiency of 39.6%.
A novel toll-like receptor from Mytilus coruscus is induced in response to stress.
Xu, Mengshan; Wu, Jiong; Ge, Delong; Wu, Changwen; Changfeng Chi; Lv, Zhenming; Liao, Zhi; Liu, Huihui
2018-07-01
Toll-like receptor (TLR) is considered to be an evolutionarily conserved transmembrane protein which promotes the Toll signal pathway to active the expression of transcription factors in the innate immunity of the organism. In this study, a full length of TLR homologue of 2525bp in Mytilus coruscus (named as McTLR-a, GenBank accession no: KY940571) was characterized. Its ORF was 1815 bp with a 5'untranslated region (UTR) of 128 bp and a 3'UTR of 582 bp, encoding 602 amino acid residues with a calculated molecular weight of 70.870 kDa (pI = 6.10). BLASTn analysis and phylogenetic relationship strongly suggested that this cDNA sequence was a member of TLR family. Quantitative real time RT-PCR showed that constitutive expression of McTLR-a was occurred, with increasing order in hemocyte, gonad, mantle, adducter, gill and hepatopancreas. Bacterial infection and heavy metals stimulation up-regulated the expression of McTLR-a mRNA in hepatopancreas with time-dependent manners. The maximum expression appeared at 12 h after pathogenic bacteria injection, with approximately 22-fold in Aeromonas hydrophila and 17-fold in Vibrio parahemolyticus higher than that of the blank group. In heavy metals stress group, they all reached peaks at 3d, while the diverse concentration caused the maximum expression were different. The highest expression reached approximately 7-fold higher than the blank in low concentration of Pb 2+ exposure. In Cu 2+ treated group, it reached the peak (approximately 12-fold higher than the blank)in middle concentration. These results indicated that McTLR-a might be involved in the defense response and had a significant role in mediating the environmental stress. Copyright © 2018 Elsevier Ltd. All rights reserved.
Keil, Nina M; Pommereau, Marc; Patt, Antonia; Wechsler, Beat; Gygax, Lorenz
2017-02-01
Confined goats spend a substantial part of the day feeding. A poorly designed feeding place increases the risk of feeding in nonphysiological body postures, and even injury. Scientifically validated information on suitable dimensions of feeding places for loose-housed goats is almost absent from the literature. The aim of the present study was, therefore, to determine feeding place dimensions that would allow goats to feed in a species-appropriate, relaxed body posture. A total of 27 goats with a height at the withers of 62 to 80 cm were included in the study. Goats were tested individually in an experimental feeding stall that allowed the height difference between the feed table, the standing area of the forelegs, and a feeding area step (difference in height between forelegs and hind legs) to be varied. The goats accessed the feed table via a palisade feeding barrier. The feed table was equipped with recesses at varying distances to the feeding barrier (5-55 cm in 5-cm steps) at angles of 30°, 60°, 90°, 120°, or 150° (feeding angle), which were filled with the goats' preferred food. In 18 trials, balanced for order across animals, each animal underwent all possible combinations of feeding area step (3 levels: 0, 10, and 20 cm) and of difference in height between feed table and standing area of forelegs (6 levels: 0, 5, 10, 15, 20, and 25 cm). The minimum and maximum reach at which the animals could reach feed on the table with a relaxed body posture was determined for each combination. Statistical analysis was performed using mixed-effects models. The animals were able to feed with a relaxed posture when the feed table was at least 10 cm higher than the standing height of the goats' forelegs. Larger goats achieved smaller minimum reaches and minimum reach increased if the goats' head and neck were angled. Maximum reach increased with increasing height at withers and height of the feed table. The presence of a feeding area step had no influence on minimum and maximum reach. Based on these results, the goats' feeding place can be designed to ensure that the animals are able to reach all of the feed in the manger or on the feed table with a relaxed posture, thus avoiding injuries and nonphysiological stress on joints and hooves. A feeding area step up to a maximum of 20 cm need not be taken into account in terms of feeding reach. However, the feed table must be raised at least 10 cm above the standing area to allow the goats to feed in a species-appropriate, relaxed posture. Copyright © 2017 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.
Freeman, Laura A; Anwer, Bilal; Brady, Ryan P; Smith, Benjamin C; Edelman, Theresa L; Misselt, Andrew J; Cressman, Erik N K
2010-03-01
To measure and compare temperature changes in a recently developed gel phantom for thermochemical ablation as a function of reagent strength and concentration with several acids and bases. Aliquots (0.5-1 mL) of hydrochloric acid or acetic acid and sodium hydroxide or aqueous ammonia were injected for 5 seconds into a hydrophobic gel phantom. Stepwise increments in concentration were used to survey the temperature changes caused by these reactions. Injections were performed in triplicate, measured with a thermocouple probe, and plotted as functions of concentration and time. Maximum temperatures were reached almost immediately in all cases, reaching 75 degrees C-110 degrees C at the higher concentrations. The highest temperatures were seen with hydrochloric acid and either base. More concentrated solutions of sodium hydroxide tended to mix incompletely, such that experiments at 9 M and higher were difficult to perform consistently. Higher concentrations for any reagent resulted in higher temperatures. Stronger acid and base combinations resulted in higher temperatures versus weak acid and base combinations at the same concentration. Maximum temperatures obtained are in a range known to cause tissue coagulation, and all combinations tested therefore appeared suitable for further investigation in thermochemical ablation. Because of the loss of the reaction chamber shape at higher concentrations of stronger agents, the phantom does not allow complete characterization under these circumstances. Adequate mixing of reagents to maximize heating potential and avoid systemic exposure to unreacted acid and base must be addressed if the method is to be safely employed in tissues. In addition, understanding factors that control lesion shape in a more realistic tissue model will be critical. Copyright 2010 SIR. Published by Elsevier Inc. All rights reserved.
Analyses of ozone in urban and rural sites in Málaga (Spain).
Dueñas, C; Fernández, M C; Cañete, S; Carretero, J; Liger, E
2004-08-01
Ozone concentrations were measured at two (urban and a rural) sites near the city of Málaga (Spain). The aim of this study was to determine the daily, monthly and seasonal variation patterns of ozone concentrations at both sites and to study the possible regional influences. The daily variations mostly have the usual features with the afternoon maximum and the night minimum being more pronounced in the urban area. The average monthly concentrations throughout the year start to increase in March reaching their maximum values in July for the urban site. However, in the rural area, the monthly variations are smaller reaching their maximum value in June. The hourly evolution of the ozone concentrations in both sampling sites is well defined in spring and summer and not so well defined in autumn and winter. Taking into account the four seasons, the rural concentrations are higher than the urban ones. Summer is the season when there are similar concentrations at both sampling sites. Average hourly summer afternoon ozone for the hours 12:00-20:00 LST exceeded the 110 microg m(-3) European Union guidelines for human health for 8 h ozone exposure at the urban and rural sites.
Electricity generation directly using human feces wastewater for life support system
NASA Astrophysics Data System (ADS)
Fangzhou, Du; Zhenglong, Li; Shaoqiang, Yang; Beizhen, Xie; Hong, Liu
2011-05-01
Wastewater reuse and power regeneration are key issues in the research of bioregeneration life support system (BLSS). Microbial fuel cell (MFC) can generate electricity during the process of wastewater treatment, which might be promising to solve the two problems simultaneously. We used human feces wastewater containing abundant organic compounds as the substrate of MFC to generate electricity, and the factors concerning electricity generation capacity were investigated. The removal efficiency of total chemical oxygen demand (TCOD), Soluble chemical oxygen demand (SCOD) and NH4+ reached 71%, 88% and 44%, respectively with two-chamber MFC when it was fed with the actual human feces wastewater and operated for 190 h. And the maximum power density reached 70.8 mW/m 2, which implicated that MFC technology was feasible and appropriate for treating human feces wastewater. In order to improve the power generation of MFC further, human feces wastewater were fermented before poured into MFC, and the result showed that fermentation pretreatment could improve the MFC output obviously. The maximum power density of MFC fed with pretreated human feces wastewater was 22 mW/m 2, which was 47% higher than that of the control without pretreatment (15 mW/m 2). Furthermore, the structure of MFC was studied and it was found that both enlarging the area of electrodes and shortening the distance between electrodes could increase the electricity generation capacity. Finally, an automatic system, controlled by time switches and electromagnetic valves, was established to process one person's feces wastewater (1 L/d) while generating electricity. The main parts of this system comprised a pretreatment device and 3 one-chamber air-cathode MFCs. The total power could reach 787.1 mW and power density could reach the maximum of about 240 mW/m 2.
Hawari, Alaa; Ramadan, Hasanat; Abu-Reesh, Ibrahim; Ouederni, Mabrouk
2015-03-15
The treatment of spent caustic produced from an ethylene plant was investigated. In the case of neutralization alone it was found that the maximum removal of sulfide was at pH values below 5.5. The higher percentage removal of sulfides (99% at pH = 1.5) was accompanied with the highest COD removal (88%). For classical oxidation using H2O2 the maximum COD removal percentage reached 89% at pH = 2.5 and at a hydrogen peroxide concentration of 19 mM/L. For the advanced oxidation using Fenton's process it was found that the maximum COD removal of 96.5% was achieved at a hydrogen peroxide/ferrous sulfate ratio of (7:1). Copyright © 2014 Elsevier Ltd. All rights reserved.
Radtka, Sandra; Zayac, Jacqueline; Goldberg, Krystyna; Long, Michael; Ixanov, Rustem
2017-03-01
This study determined test-retest reliability of trunk and pelvis joint angles, arm distance and center of pressure (COP) excursion for the seated functional reach test (FRT) and compared these variables during the seated FRT with and without foot support. Fifteen typically developing children (age 9.3±4.1years) participated. Trunk and pelvis joint angles, arm distance, and COP excursion were collected on two days using three-dimensional motion analysis and a force plate while subjects reached maximally with and without foot support in the anterior, anterior/lateral, lateral, posterior/lateral directions. Age, weight, height, trunk and arm lengths were correlated (p<0.01) with maximum arm distance reached. Maximum arm distance, trunk and pelvis joint angles, and COP with and without foot support were not significant (p<0.05) for the two test periods. Excellent reliability (ICCs>0.75) was found for maximum arm distance reached in all four directions in the seated FRT with and without foot support. Most trunk and pelvis joint angles and COP excursions during maximum reach in all four directions showed excellent to fair reliability (ICCs>0.40-0.75). Reaching with foot support in all directions was significantly greater (p<0.05) than without foot support; however, most COP excursions and trunk and pelvic angles were not significantly different. Findings support the addition of anterior/lateral and posterior/lateral reaching directions in the seated FRT. Trunk and pelvis movement analysis is important to examine in the seated FRT to determine the specific movement strategies needed for maximum reaching without loss of balance. Copyright © 2017 Elsevier B.V. All rights reserved.
Negative to positive magnetoresistance and magnetocaloric effect in Pr 0.6Er 0.4Al 2
Pathak, Arjun K.; Gschneidner, Jr., K. A.; Pecharsky, V. K.
2014-10-13
We report on the magnetic, magnetocaloric and magnetotransport properties of Pr 0.6Er 0.4Al 2. The title compound exhibits a large positive magnetoresistance (MR) for H ≥ 40 kOe and a small but non negligible negative MR for H ≤ 30 kOe. The maximum positive MR reaches 13% at H = 80 kOe. The magnetic entropy and adiabatic temperature changes as functions of temperature each show two anomalies: a broad dome-like maximum below 20 K and a relatively sharp peak at higher temperature. As a result, observed behaviors are unique among other binary and mixed lanthanide compounds.
Fitzgerald, Paul J
2014-07-01
It is of high clinical interest to better understand the timecourse through which psychiatric drugs produce their beneficial effects. While a rough estimate of the time lag between initiating monoaminergic antidepressant therapy and the onset of therapeutic effect in depressed subjects is two weeks, much less is known about when these drugs reach maximum effect. This paper briefly examines studies that directly address this question through long-term antidepressant administration to humans, while also putting forth a simple theoretical approach for estimating the time required for monoaminergic antidepressants to reach maximum therapeutic effect in humans. The theory invokes a comparison between speed of antidepressant drug response in humans and in rodents, focusing on the apparently greater speed in rodents. The principal argument is one of proportions, comparing earliest effects of these drugs in rodents and humans, versus their time to reach maximum effect in these organisms. If the proportionality hypothesis is even coarsely accurate, then applying these values or to some degree their ranges to the hypothesis, may suggest that monoaminergic antidepressants require a number of years to reach maximum effect in humans, at least in some individuals.
Fatehi, Pedram; Shen, Jing; Hamdan, Fadia C; Ni, Yonghao
2013-02-15
In this work, the adsorption of lignocelluloses of pre-hydrolysis liquor (PHL) on precipitated calcium carbonate (PCC) was studied in the presence of poly diallyldimethylammonium chloride (PDADMAC) or cationic polyacrylamide (CPAM). The results revealed that adding PCC to PHL and subsequently adding cationic polymers to PHL/PCC systems was more effective than adding cationic polymers to PHL and then adding PCC to the cationic polymer/PHL systems. At the same dosage applied, PDADMAC resulted in a higher adsorption of lignocelluloses on PCC than CPAM did due to its higher charge density. The adsorption of lignocelluloses on PCC reached its maximum in 3h, and a high temperature reduced the adsorption level as the adsorption was an exothermic process. The maximum adsorptions of 530 mg/g oligo-sugars, 203 mg/g lignin and 58 mg/g furfural on PCC were achieved via adding 0.8 mg/g PDADMAC2 (i.e. higher MW PDADMAC) to PCC/PHL system. Copyright © 2012 Elsevier Ltd. All rights reserved.
2012-01-01
Background Previous studies demonstrated that stroke survivors have a limited capacity to increase their walking speeds beyond their self-selected maximum walking speed (SMWS). The purpose of this study was to determine the capacity of stroke survivors to reach faster speeds than their SMWS while walking on a treadmill belt or while being pushed by a robotic system (i.e. “push mode”). Methods Eighteen chronic stroke survivors with hemiplegia were involved in the study. We calculated their self-selected comfortable walking speed (SCWS) and SMWS overground using a 5-meter walk test (5-MWT). Then, they were exposed to walking at increased speeds, on a treadmill and while in “push mode” in an overground robotic device, the KineAssist, until they were tested at a speed that they could not sustain without losing balance. We recorded the time and number of steps during each trial and calculated gait speed, average cadence and average step length. Results Maximum walking speed in the “push mode” was 13% higher than the maximum walking speed on the treadmill and both were higher (“push mode”: 61%; treadmill: 40%) than the maximum walking speed overground. Subjects achieved these faster speeds by initially increasing both step length and cadence and, once individuals stopped increasing their step length, by only increasing cadence. Conclusions With post-stroke hemiplegia, individuals are able to walk at faster speeds than their SMWS overground, when provided with a safe environment that provides external forces that requires them to attempt dynamic stability maintenance at higher gait speeds. Therefore, this study suggests the possibility that, given the appropriate conditions, people post-stroke can be trained at higher speeds than previously attempted. PMID:23057500
Patterson, Carson; Raschner, Christian; Platzer, Hans-Peter
2009-05-01
The purpose of this paper was to investigate the power-load relationship and to compare power variables and bilateral force imbalances between sexes with squat jumps. Twenty men and 17 women, all members of the Austrian alpine ski team (junior and European Cup), performed unloaded and loaded (barbell loads equal to 25, 50, 75, and 100% body weight [BW]) squat jumps with free weights using a specially designed spotting system. Ground reaction force records from 2 force platforms were used to calculate relative average power (P), relative average power in the first 100 ms of the jump (P01), relative average power in the first 200 ms of the jump (P02), jump height, percentage of best jump height (%Jump), and maximal force difference between dominant and nondominant leg (Fmaxdiff). The men displayed significantly higher values at all loads for P and jump height (p < 0.05). No significant differences were found in P01. The men had significantly higher P02 at all loads except 75% BW). Maximum P was reached at light loads (men at 25% BW and women at 0% BW), and P decreased uniformly thereafter. Individual power-load curves show a deflection point. It is proposed that the load where the power-load deflection point occurs be used as the power training load and not the load at which maximum P is reached. It is also proposed that loads not be described in %1-repetition maximum (RM), but as %BW. This system can be used to safely assess and train power with loaded jumps and free weights.
NASA Astrophysics Data System (ADS)
Menéndez, M.; Comín, F. A.
2000-08-01
During the last 10 years, a drastic change in the structure of the community of primary producers has been observed in Tancada Lagoon (Ebro Delta, NE Spain). This consisted of a decrease in the abundance of submerged rooted macrophyte cover and a spring and summer increase in floating macroalgae. Two spatial patterns have been observed. In the west part of the lagoon, Chaetomorpha linum Kützing, dominated during winter and decreased progressively in spring when Cladophora sp. reached its maximum development. In the east part of the lagoon, higher macroalgal diversity was observed, together with lower cover in winter and early spring. Cladophora sp., Gracilaria verrucosa Papenfuss and Chondria tenuissima Agardh, increased cover and biomass in summer. Maximum photosynthetic production was observed in spring for G. verrucosa (10·9 mg O 2 g -1 DW h -1) and C. tenuissima (19·0 mg O 2 g -1 DW h -1) in contrast with Cladophora sp. (15·9 mg O 2 g -1 DW h -1) and Chaetomorpha linum (7·2 mg O 2 g -1 DW h -1) which reached maximum production in summer. Increased conductivity from reduced freshwater inflow, and higher water temperatures during periods of lagoon isolation, mainly in summer, were the main physical factors associated with an increase in floating macroalgal biomass across the lagoon. Reduced nitrogen availability and temperature-related changes in carbon availability during summer were related to a decrease in abundance of C. linum and increases in G. verrucosa and Cladophora sp.
Zheljazkov, Valtcho D; Gawde, Archana; Cantrell, Charles L; Astatkie, Tess; Schlegel, Vicki
2015-01-01
A steam distillation extraction kinetics experiment was conducted to estimate essential oil yield, composition, antimalarial, and antioxidant capacity of cumin (Cuminum cyminum L.) seed (fruits). Furthermore, regression models were developed to predict essential oil yield and composition for a given duration of the steam distillation time (DT). Ten DT durations were tested in this study: 5, 7.5, 15, 30, 60, 120, 240, 360, 480, and 600 min. Oil yields increased with an increase in the DT. Maximum oil yield (content, 2.3 g/100 seed), was achieved at 480 min; longer DT did not increase oil yields. The concentrations of the major oil constituents α-pinene (0.14-0.5% concentration range), β-pinene (3.7-10.3% range), γ-cymene (5-7.3% range), γ-terpinene (1.8-7.2% range), cumin aldehyde (50-66% range), α-terpinen-7-al (3.8-16% range), and β-terpinen-7-al (12-20% range) varied as a function of the DT. The concentrations of α-pinene, β-pinene, γ-cymene, γ-terpinene in the oil increased with the increase of the duration of the DT; α-pinene was highest in the oil obtained at 600 min DT, β-pinene and γ-terpinene reached maximum concentrations in the oil at 360 min DT; γ-cymene reached a maximum in the oil at 60 min DT, cumin aldehyde was high in the oils obtained at 5-60 min DT, and low in the oils obtained at 240-600 min DT, α-terpinen-7-al reached maximum in the oils obtained at 480 or 600 min DT, whereas β-terpinen-7-al reached a maximum concentration in the oil at 60 min DT. The yield of individual oil constituents (calculated from the oil yields and the concentration of a given compound at a particular DT) increased and reached a maximum at 480 or 600 min DT. The antimalarial activity of the cumin seed oil obtained during the 0-5 and at 5-7.5 min DT timeframes was twice higher than the antimalarial activity of the oils obtained at the other DT. This study opens the possibility for distinct marketing and utilization for these improved oils. The antioxidant capacity of the oil was highest in the oil obtained at 30 min DT and lowest in the oil from 360 min DT. The Michaelis-Menton and the Power nonlinear regression models developed in this study can be utilized to predict essential oil yield and composition of cumin seed at any given duration of DT and may also be useful to compare previous reports on cumin oil yield and composition. DT can be utilized to obtain cumin seed oil with improved antimalarial activity, improved antioxidant capacity, and with various compositions.
Structural analysis of three space crane articulated-truss joint concepts
NASA Technical Reports Server (NTRS)
Wu, K. Chauncey; Sutter, Thomas R.
1992-01-01
Three space crane articulated truss joint concepts are studied to evaluate their static structural performance over a range of geometric design parameters. Emphasis is placed on maintaining the four longeron reference truss performance across the joint while allowing large angle articulation. A maximum positive articulation angle and the actuator length ratio required to reach the angle are computed for each concept as the design parameters are varied. Configurations with a maximum articulation angle less than 120 degrees or actuators requiring a length ratio over two are not considered. Tip rotation and lateral deflection of a truss beam with an articulated truss joint at the midspan are used to select a point design for each concept. Deflections for one point design are up to 40 percent higher than for the other two designs. Dynamic performance of the three point design is computed as a function of joint articulation angle. The two lowest frequencies of each point design are relatively insensitive to large variations in joint articulation angle. One point design has a higher maximum tip velocity for the emergency stop than the other designs.
NASA Astrophysics Data System (ADS)
Liu, Ningwei; Ren, Wanhui; Li, Xiaolan; Ma, Xiaogang; Zhang, Yunhai; Li, Bingkun
2018-03-01
Hourly mixing ratio data of ground-level ozone and its main precursors at ambient air quality monitoring sites in Shenyang during 2013-2015 were used to survey spatiotemporal variations in ozone. Then, the transport of ozone and its precursors among urban, suburban, and rural sites was examined. The correlations between ozone and some key meteorological factors were also investigated. Ozone and O x mixing ratios in Shenyang were higher during warm seasons and lower during cold ones, while ozone precursors followed the opposite cycle. Ozone mixing ratios reached maximum and minimum values in the afternoon and morning, respectively, reflecting the significant influence of photochemical production during daytime and depletion via titration during nighttime. Compared to those in downtown Shenyang, ozone mixing ratios were higher and the occurrence of peak values were later in suburban and rural areas downwind of the prevailing wind. The differences were most significant in summer, when the ozone mixing ratios at one suburban downwind site reached a maximum value of 35.6 ppb higher than those at the downtown site. This suggests that photochemical production processes were significant during the transport of ozone precursors, particularly in warm seasons with sufficient sunlight. Temperature, total radiation, and wind speed all displayed positive correlations with ozone concentration, reflecting their important role in accelerating ozone formation. Generally, the correlations between ozone and meteorological factors were slightly stronger at suburban sites than in urban areas, indicating that ozone levels in suburban areas were more sensitive to these meteorological factors.
Cai, Michael; Castro Salgado, Jacqueline
2018-01-01
Calcium hydroxide’s anti-bacterial action relies on high pH. The aim here was to investigate hydroxyl ion diffusion through dentine under different conditions. Teeth were divided into control (n = 4) and four experimental groups (n = 10): Group 1—no medicament; Group 2—Calmix; Group 3—Calmix/Ledermix; Group 4—Calasept Plus/Ledermix; Group 5—Pulpdent/smear layer. Deep (inner dentine) and shallow (outer dentine) cavities were cut into each root. pH was measured in these cavities for 12 weeks. The inner and outer dentine pH in Group 2 was significantly higher than all groups. Inner dentine pH in Group 3 was slightly higher than that in Group 4 initially but subsequently comparable. After Day 2, Group 5 had significantly lower pH than Groups 3 and 4. The outer dentine pH in Group 3 started higher than that in Groups 4 and 5, but by Day 28 the difference was insignificant. The time for the inner dentine to reach maximum pH was one week for Group 2 and four weeks for Groups 3 and 4. The time for the outer dentine to reach maximum pH was eight weeks for all experimental groups. Mixing different Ca(OH)2 formulations with Ledermix gave similar hydroxyl ion release but pH and total diffusion was lower than Ca(OH)2 alone. The smear layer inhibited diffusion. PMID:29342093
Production of tannase by the immobilized cells of Bacillus licheniformis KBR6 in Ca-alginate beads.
Mohapatra, P K D; Mondal, K C; Pati, B R
2007-06-01
The present study was aimed at finding the optimal conditions for immobilization of Bacillus licheniformis KBR6 cells in calcium-alginate (Ca-alginate) beads and determining the operational stability during the production of tannin-acyl-hydrolase (tannase) under semicontinous cultivation. The active cells of B. licheniformis KBR6 were immobilized in Ca-alginate and used for the production of tannase. The influence of alginate concentration (5, 10, 20 and 30 g l(-1)) and initial cell loading on enzyme production were studied. The production of tannase increased significantly with increasing alginate concentration and reached a maximum enzyme yield of 0.56 +/- 0.03 U ml(-1) at 20 g l(-1). This was about 1.70-fold higher than that obtained by free cells. The immobilized cells produced tannase consistently over 13 repeated cycles and reached a maximum level at the third cycle. Scanning electron microscope study indicated that the cells in Ca-alginate beads remain in normal shape. The Ca-alginate entrapment is a promising immobilization method of B. licheniformis KBR6 for repeated tannase production. Tannase production by immobilized cells is superior to that of free cells because it leads to higher volumetric activities within the same period of fermentation. This is the first report of tannase production from immobilized bacterial cells. The bacterium under study can produce higher amounts of tannase with respect to other fungal strains within a short cultivation period.
Gutiérrez, M C; Siles, J A; Diz, J; Chica, A F; Martín, M A
2017-01-01
The composting process of six different compostable substrates and one of these with the addition of bacterial inoculums carried out in a dynamic respirometer was evaluated. Despite the heterogeneity of the compostable substrates, cumulative oxygen demand (OD, mgO 2 kgVS) was fitted adequately to an exponential regression growing until reaching a maximum in all cases. According to the kinetic constant of the reaction (K) values obtained, the wastes that degraded more slowly were those containing lignocellulosic material (green wastes) or less biodegradable wastes (sewage sludge). The odor emissions generated during the composting processes were also fitted in all cases to a Gaussian regression with R 2 values within the range 0.8-0.9. The model was validated representing real odor concentration near the maximum value against predicted odor concentration of each substrate, (R 2 =0.9314; 95% prediction interval). The variables of maximum odor concentration (ou E /m 3 ) and the time (h) at which the maximum was reached were also evaluated statistically using ANOVA and a post-hoc Tukey test taking the substrate as a factor, which allowed homogeneous groups to be obtained according to one or both of these variables. The maximum oxygen consumption rate or organic matter degradation during composting was directly related to the maximum odor emission generation rate (R 2 =0.9024, 95% confidence interval) when only the organic wastes with a low content in lignocellulosic materials and no inoculated waste (HRIO) were considered. Finally, the composting of OFMSW would produce a higher odor impact than the other substrates if this process was carried out without odor control or open systems. Copyright © 2016 Elsevier Ltd. All rights reserved.
ERIC Educational Resources Information Center
de Abreu, Daniela Cristina Carvalho; Takara, Kelly; Metring, Nathalia Lopes; Reis, Julia Guimaraes; Cliquet, Alberto, Jr.
2012-01-01
We aimed to evaluate the influence of different types of wheelchair seats on paraplegic individuals' postural control using a maximum anterior reaching test. Balance evaluations during 50, 75, and 90% of each individual's maximum reach in the forward direction using two different cushions on seat (one foam and one gel) and a no-cushion condition…
Computer-aided interpretation approach for optical tomographic images
NASA Astrophysics Data System (ADS)
Klose, Christian D.; Klose, Alexander D.; Netz, Uwe J.; Scheel, Alexander K.; Beuthan, Jürgen; Hielscher, Andreas H.
2010-11-01
A computer-aided interpretation approach is proposed to detect rheumatic arthritis (RA) in human finger joints using optical tomographic images. The image interpretation method employs a classification algorithm that makes use of a so-called self-organizing mapping scheme to classify fingers as either affected or unaffected by RA. Unlike in previous studies, this allows for combining multiple image features, such as minimum and maximum values of the absorption coefficient for identifying affected and not affected joints. Classification performances obtained by the proposed method were evaluated in terms of sensitivity, specificity, Youden index, and mutual information. Different methods (i.e., clinical diagnostics, ultrasound imaging, magnet resonance imaging, and inspection of optical tomographic images), were used to produce ground truth benchmarks to determine the performance of image interpretations. Using data from 100 finger joints, findings suggest that some parameter combinations lead to higher sensitivities, while others to higher specificities when compared to single parameter classifications employed in previous studies. Maximum performances are reached when combining the minimum/maximum ratio of the absorption coefficient and image variance. In this case, sensitivities and specificities over 0.9 can be achieved. These values are much higher than values obtained when only single parameter classifications were used, where sensitivities and specificities remained well below 0.8.
Is applicable thermodynamics of negative temperature for living organisms?
NASA Astrophysics Data System (ADS)
Atanasov, Atanas Todorov
2017-11-01
During organismal development the moment of sexual maturity can be characterizes by nearly maximum basal metabolic rate and body mass. Once the living organism reaches extreme values of the mass and the basal metabolic rate, it reaches near equilibrium thermodynamic steady state physiological level with maximum organismal complexity. Such thermodynamic systems that reach equilibrium steady state level at maximum mass-energy characteristics can be regarded from the prospective of thermodynamics of negative temperature. In these systems the increase of the internal and free energy is accompanied with decrease of the entropy. In our study we show the possibility the living organisms to regard as thermodynamic system with negative temperature
Snow, topography, and the diurnal cycle in streamflow
Lundquist, J.D.; Knowles, N.; Dettinger, M.; Cayan, D.
2002-01-01
Because snowmelt processes are spatially complex, point measurements, particularly in mountainous regions, are often inadequate to resolve basin-scale characteristics. Satellite measurements provide good spatial sampling but are often infrequent in time, particularly during cloudy weather. Fortunately, hourly measurements of river discharge provide another widely available, but as yet underutilized, source of information, providing direct information on basin output at a fine temporal scale. The hour of maximum discharge recorded each day reflects the travel time between peak melt and the time most water reaches the gauge. Traditional theories, based on numerical models of melt-water percolation through a snowpack and localized, small-basin observations, report that the hour of daily maximum flow becomes earlier as the snowpack thins and matures, reflecting shorter travel times for surface melt to reach the base of the snowpack. However, an examination of hourly discharge from 100 basins in the Western United States, ranging in size from 1.3 km2 to 10,813 km2, reveals a more complex situation. The sequences of seasonal evolution of the hour of maximum discharge are unique to each basin, but within a given basin are remarkably consistent between years, regardless of the size of the snowpack. This seems to imply that basin topography strongly influences the timing of peak flow. In most of the basins examined, at the end of the melt season, the hour of maximum discharge shifts to later in the day, reflecting increased travel times as the snowline retreats to higher elevations.
White, Peter A
2013-01-01
How accurate are explicit judgements about familiar forms of object motion, and how are they made? Participants judged the relations between force exerted in kicking a soccer ball and variables that define the trajectory of the ball: launch angle, maximum height attained, and maximum distance reached. Judgements tended to conform to a simple heuristic that judged force tends to increase as maximum height and maximum distance increase, with launch angle not being influential. Support was also found for the converse prediction, that judged maximum height and distance tend to increase as the amount of force described in the kick increases. The observed judgemental tendencies did not resemble the objective relations, in which force is a function of interactions between the trajectory variables. This adds to a body of research indicating that practical knowledge based on experiences of actions on objects is not available to the processes that generate judgements in higher cognition and that such judgements are generated by simple rules that do not capture the objective interactions between the physical variables.
Ni, Xiang; Liu, Chuntao; Zhang, Qinghong; Cecil, Daniel J.
2018-01-01
A 16-yr record of hail reports over the south U.S. and from weather stations in China are collocated with Precipitation Features (PF) derived from the Tropical Rainfall Measuring Mission (TRMM) radar and passive microwave observations. Differences in the way hail is reported in the two nations make it difficult to draw meaningful conclusions about storm frequency. But taking the two together yields a wide spectrum of hail sizes, suitable for comparing with remote sensing measurements. While U.S. hail reports are dominated by cases with hail size greater than 19 mm, hail reports in China mostly include diameters of 1–10 mm and mostly occur over the Tibetan Plateau. The fraction of PFs collocated with hail reports (hail PFs) reaches 3% in the plains of the U.S. In China, the fraction is higher in high elevation regions than low elevation regions. Hail PFs (as reported in the U.S.) show lower brightness temperatures, higher lightning flash rates, stronger maximum reflectivity, and higher echo tops than those with smaller hail, as reported in China. The average near surface maximum reflectivity of hail PFs at high elevations (≥ 2000 m) in China is about 5 dB smaller than those at low elevations. Larger hail is reported with PFs having stronger maximum reflectivity above 6 km, though the median of maximum reflectivity values at levels below 5 km is similar among the storms with large and small hail sizes. PMID:29377045
Motor unit firing rate patterns during voluntary muscle force generation: a simulation study
NASA Astrophysics Data System (ADS)
Hu, Xiaogang; Rymer, William Z.; Suresh, Nina L.
2014-04-01
Objective. Muscle force is generated by a combination of motor unit (MU) recruitment and changes in the discharge rate of active MUs. There have been two basic MU recruitment and firing rate paradigms reported in the literature, which describe the control of the MUs during force generation. The first (termed the reverse ‘onion skin’ profile), exhibits lower firing rates for lower threshold units, with higher firing rates occurring in higher threshold units. The second (termed the ‘onion skin’ profile), exhibits an inverse arrangement, with lower threshold units reaching higher firing rates. Approach. Using a simulation of the MU activity in a hand muscle, this study examined the force generation capacity and the variability of the muscle force magnitude at different excitation levels of the MU pool under these two different MU control paradigms. We sought to determine which rate/recruitment scheme was more efficient for force generation, and which scheme gave rise to the lowest force variability. Main results. We found that the force output of both firing patterns leads to graded force output at low excitation levels, and that the force generation capacity of the two different paradigms diverged around 50% excitation. In the reverse ‘onion skin’ pattern, at 100% excitation, the force output reached up to 88% of maximum force, whereas for the ‘onion skin’ pattern, the force output only reached up to 54% of maximum force at 100% excitation. The force variability was lower at the low to moderate force levels under the ‘onion skin’ paradigm than with the reverse ‘onion skin’ firing patterns, but this effect was reversed at high force levels. Significance. This study captures the influence of MU recruitment and firing rate organization on muscle force properties, and our results suggest that the different firing organizations can be beneficial at different levels of voluntary muscle force generation and perhaps for different tasks.
Reconfigurable multiport EPON repeater
NASA Astrophysics Data System (ADS)
Oishi, Masayuki; Inohara, Ryo; Agata, Akira; Horiuchi, Yukio
2009-11-01
An extended reach EPON repeater is one of the solutions to effectively expand FTTH service areas. In this paper, we propose a reconfigurable multi-port EPON repeater for effective accommodation of multiple ODNs with a single OLT line card. The proposed repeater, which has multi-ports in both OLT and ODN sides, consists of TRs, BTRs with the CDR function and a reconfigurable electrical matrix switch, can accommodate multiple ODNs to a single OLT line card by controlling the connection of the matrix switch. Although conventional EPON repeaters require full OLT line cards to accommodate subscribers from the initial installation stage, the proposed repeater can dramatically reduce the number of required line cards especially when the number of subscribers is less than a half of the maximum registerable users per OLT. Numerical calculation results show that the extended reach EPON system with the proposed EPON repeater can save 17.5% of the initial installation cost compared with a conventional repeater, and can be less expensive than conventional systems up to the maximum subscribers especially when the percentage of ODNs in lightly-populated areas is higher.
Li, Yinping; Cui, Jiefen; Zhang, Gaoli; Liu, Zhengkun; Guan, Huashi; Hwang, Hueymin; Aker, Winfred G; Wang, Peng
2016-08-01
The seaweed Ulva prolifera, distributed in inter-tidal zones worldwide, contains a large percentage of cellulosic materials. The technical feasibility of using U. prolifera residue (UPR) obtained after extraction of polysaccharides as a renewable energy resource was investigated. An environment-friendly and economical pretreatment process was conducted using hydrogen peroxide. The hydrogen peroxide pretreatment improved the efficiency of enzymatic hydrolysis. The resulting yield of reducing sugar reached a maximum of 0.42g/g UPR under the optimal pretreatment condition (hydrogen peroxide 0.2%, 50°C, pH 4.0, 12h). The rate of conversion of reducing sugar in the concentrated hydrolysates to bioethanol reached 31.4% by Saccharomyces cerevisiae fermentation, which corresponds to 61.7% of the theoretical maximum yield. Compared with other reported traditional processes on Ulva biomass, the reducing sugar and bioethanol yield are substantially higher. Thus, hydrogen peroxide pretreatment is an effective enhancement of the process of bioethanol production from the seaweed U. prolifera. Copyright © 2016 Elsevier Ltd. All rights reserved.
Scaling behavior for random walks with memory of the largest distance from the origin
NASA Astrophysics Data System (ADS)
Serva, Maurizio
2013-11-01
We study a one-dimensional random walk with memory. The behavior of the walker is modified with respect to the simple symmetric random walk only when he or she is at the maximum distance ever reached from his or her starting point (home). In this case, having the choice to move farther or to move closer, the walker decides with different probabilities. If the probability of a forward step is higher then the probability of a backward step, the walker is bold, otherwise he or she is timorous. We investigate the asymptotic properties of this bold-timorous random walk, showing that the scaling behavior varies continuously from subdiffusive (timorous) to superdiffusive (bold). The scaling exponents are fully determined with a new mathematical approach based on a decomposition of the dynamics in active journeys (the walker is at the maximum distance) and lazy journeys (the walker is not at the maximum distance).
Martinelli, Nicolo; Baretta, Silvia; Pagano, Jenny; Bianchi, Alberto; Villa, Tomaso; Casaroli, Gloria; Galbusera, Fabio
2017-11-25
Mobile-bearing ankle implants with good clinical results continued to increase the popularity of total ankle arthroplasty to address endstage ankle osteoarthritis preserving joint movement. Alternative solutions used fixed-bearing designs, which increase stability and reduce the risk of bearing dislocation, but with a theoretical increase of contact stresses leading to a higher polyethylene wear. The purpose of this study was to investigate the contact stresses, pressure and area in the polyethylene component of a new total ankle replacement with a fixed-bearing design, using 3D finite element analysis. A three-dimensional finite element model of the Zimmer Trabecular Metal Total Ankle was developed and assembled based on computed tomography images. Three different sizes of the polyethylene insert were modeled, and a finite element analysis was conducted to investigate the contact pressure, the von Mises stresses and the contact area of the polyethylene component during the stance phase of the gait cycle. The peak value of pressure was found in the anterior region of the articulating surface, where it reached 19.8 MPa at 40% of the gait cycle. The average contact pressure during the stance phase was 6.9 MPa. The maximum von Mises stress of 14.1 MPa was reached at 40% of the gait cycle in the anterior section. In the central section, the maximum von Mises stress of 10.8 MPa was reached at 37% of the gait cycle, whereas in the posterior section the maximum stress of 5.4 MPa was reached at the end of the stance phase. The new fixed-bearing total ankle replacement showed a safe mechanical behavior and many clinical advantages. However, advanced models to quantitatively estimate the wear are need. To the light of the clinical advantages, we conclude that the presented prosthesis is a good alternative to the other products present in the market.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ingham, J.G.
Maximum cladding temperatures occur when the IDENT 1578 fuel pin shipping container is installed in the T-3 Cask. The maximum allowable cladding temperature of 800/sup 0/F is reached when the rate of energy deposited in the 19-pin basket reaches 400 watts. Since 45% of the energy which is generated in the fuel escapes the 19-pin basket without being deposited, mostly gamma energy, the maximum allowable rate of heat generation is 400/.55 = 727 watts. Similarly, the maximum allowable cladding temperature of 800/sup 0/F is reached when the rate of energy deposited in the 40-pin basket reaches 465 watts. Since 33%more » of the energy which is generated in the fuel escapes the 40-pin basket without being deposited, mostly gamma energy, the maximum allowable rate of heat generation is 465/.66 = 704 watts. The IDENT 1578 fuel pin shipping container therefore meets its thermal design criteria. IDENT 1578 can handle fuel pins with a decay heat load of 600 watts while maintaining the maximum fuel pin cladding temperature below 800/sup 0/F. The emissivities which were determined from the test results for the basket tubes and container are relatively low and correspond to new, shiny conditions. As the IDENT 1578 container is exposed to high temperatures for extended periods of time during the transportation of fuel pins, the emissivities will probably increase. This will result in reduced temperatures.« less
Zheljazkov, Valtcho D.; Gawde, Archana; Cantrell, Charles L.; Astatkie, Tess; Schlegel, Vicki
2015-01-01
A steam distillation extraction kinetics experiment was conducted to estimate essential oil yield, composition, antimalarial, and antioxidant capacity of cumin (Cuminum cyminum L.) seed (fruits). Furthermore, regression models were developed to predict essential oil yield and composition for a given duration of the steam distillation time (DT). Ten DT durations were tested in this study: 5, 7.5, 15, 30, 60, 120, 240, 360, 480, and 600 min. Oil yields increased with an increase in the DT. Maximum oil yield (content, 2.3 g/100 seed), was achieved at 480 min; longer DT did not increase oil yields. The concentrations of the major oil constituents α-pinene (0.14–0.5% concentration range), β-pinene (3.7–10.3% range), γ-cymene (5–7.3% range), γ-terpinene (1.8–7.2% range), cumin aldehyde (50–66% range), α-terpinen-7-al (3.8–16% range), and β-terpinen-7-al (12–20% range) varied as a function of the DT. The concentrations of α-pinene, β-pinene, γ-cymene, γ-terpinene in the oil increased with the increase of the duration of the DT; α-pinene was highest in the oil obtained at 600 min DT, β-pinene and γ-terpinene reached maximum concentrations in the oil at 360 min DT; γ-cymene reached a maximum in the oil at 60 min DT, cumin aldehyde was high in the oils obtained at 5–60 min DT, and low in the oils obtained at 240–600 min DT, α-terpinen-7-al reached maximum in the oils obtained at 480 or 600 min DT, whereas β-terpinen-7-al reached a maximum concentration in the oil at 60 min DT. The yield of individual oil constituents (calculated from the oil yields and the concentration of a given compound at a particular DT) increased and reached a maximum at 480 or 600 min DT. The antimalarial activity of the cumin seed oil obtained during the 0–5 and at 5–7.5 min DT timeframes was twice higher than the antimalarial activity of the oils obtained at the other DT. This study opens the possibility for distinct marketing and utilization for these improved oils. The antioxidant capacity of the oil was highest in the oil obtained at 30 min DT and lowest in the oil from 360 min DT. The Michaelis-Menton and the Power nonlinear regression models developed in this study can be utilized to predict essential oil yield and composition of cumin seed at any given duration of DT and may also be useful to compare previous reports on cumin oil yield and composition. DT can be utilized to obtain cumin seed oil with improved antimalarial activity, improved antioxidant capacity, and with various compositions. PMID:26641276
Yücel, G; Yeşilkaya, A; Aksu, T A; Yeğin, A; Alicigüzel, Y
1997-01-01
Erythrocytes and hemolysates from 10 normal and 10 glucose-6-phosphate dehydrogenase-deficient individuals were incubated with cumene hydroperoxide, and free radical-induced lipid peroxidation was monitored by chemiluminescence. Chemiluminescence intensities in erythrocytes of normal and deficient subjects were similar in the presence or absence of glucose-6-phosphate dehydrogenase substrates. Hemolysates of normal and deficient subjects also showed similar chemiluminescence in the absence of substrates. However, with the addition of substrates to the incubation medium, deficient hemolysates reached maximum chemiluminescence intensity within a shorter period, and maximum values were higher than in normal hemolysates. We believe this offers a new means of detection of glucose-6-phosphate dehydrogenase-deficient patients.
NASA Technical Reports Server (NTRS)
Huff, Ronald G.
1989-01-01
Tests were conducted in the NASA Lewis Research Center's Powered Lift Facility to experimentally evaluate the noise generated by a flight weight, 12 in. butterfly valve installed in a proposed vertical takeoff and landing thrust vectoring system. Fluctuating pressure measurements were made in the circular duct upstream and downstream of the valve. This data report presents the results of these tests. The maximum overall sound pressure level is generated in the duct downstream of the valve and reached a value of 180 dB at a valve pressure ratio of 2.8. At the higher valve pressure ratios the spectra downstream of the valve is broad banded with its maximum at 1000 Hz.
Venkatarajappa, P
2001-01-01
The toxic effect of Cypermethrin 10 EC (0.125, 0.25 and 0.5%) was estimated in the bodywall and digestive system of the larvae of Oryctes rhinoceros by HPLC after exposing them to different concentrations (0.125, 0.25 and 0.5%). Among the various concentrations used maximum residues were detected in bodywall (0.25%), whereas at higher concentration (0.5%) the residue detected was minimum. The treatment of Cypermethrin was found to be highly toxic upto 12 h of treatment, after which it declined reaching the minimum by 24 h. The residue of Cypermethrin could not be detected in digestive system. The experiments indicate the pesticide get concentrated in the bodywall to a maximum extent.
NASA Astrophysics Data System (ADS)
Wang, Aijun; Ye, Xiang; Cheng, Peng; Wang, Liang
2017-04-01
Estuaries are key nodes of land-ocean interaction, the associated suspended sediment processes being crucial for global and regional material fluxes and environmental health. Within estuaries, there is commonly a reach where the water turbidity is markedly higher than both landward and seaward. This elevated suspended sediment concentration (SSC) is termed the estuarine turbidity maximum (ETM). The ETM has important influences on harbor siltation, ecological conservation, and biogeochemical dynamics. Jiulongjiang estuary is a small macro-tidal estuary in southeast China coastal area, which is a typical example for estuarine ecosystem conservation and its response to catchment management. Observed results show that the tidal current is the main factor which control the variations of SSC in ETM under the normal condition. However, under the influence of typhoon event, the hydrodynamic action was strengthened and the salt water intrusion was also enhanced, and the fresh water and sediment discharged from river system increased, which led to the complicated variations of the ETM. Under the normal conditions, the maximum width of ETM was about 10 km in spring tide. However, before typhoon landed, the maximum width of the ETM was about 14 km; after the typhoon landed, the maximum width of the ETM was more than 20 km, and during the low tide stage, the width of the ETM was still 19 km which was induced by high turbidity water input from river system. The particulate organic carbon (POC) concentration reached 19.26 mg/L within the ETM at the next day after typhoon landed, which was much higher than that under normal weather condition (the maximum value was only 3.15 mg/L). During the low tide level, the POC concentration increased remarkably from upstream to the core of ETM and then decreased toward downstream, while the POC concentration decreased toward downstream during high tide level. Compared with normal weather condition, the POC concentration varied not obviously along the river channel except at the core of ETM. The existence of ETM plays a much significant role for POC trapping during the influence of typhoon event. Acknowledgement: This research was supported by the NSFC (41376070). The authors with thank Shu-ren Huang, Hai-huang Chen and Peng-fa Chen for their help in the field work.
On the Relationship Between High Speed Solar Wind Streams and Radiation Belt Electron Fluxes
NASA Technical Reports Server (NTRS)
Zheng, Yihua
2011-01-01
Both past and recent research results indicate that solar wind speed has a close connection to radiation belt electron fluxes [e.g., Paulikas and Blake, 1979; Reeves et aI., 2011]: a higher solar wind speed is often associated with a higher level of radiation electron fluxes. But the relationship can be very complex [Reeves et aI., 2011]. The study presented here provides further corroboration of this viewpoint by emphasizing the importance of a global perspective and time history. We find that all the events during years 2010 and 2011 where the >0.8 MeV integral electron flux exceeds 10(exp 5) particles/sq cm/sr/s (pfu) at GEO orbit are associated with the high speed streams (HSS) following the onset of the Stream Interaction Region (SIR), with most of them belonging to the long-lasting Corotating Interaction Region (CIR). Our preliminary results indicate that during HSS events, a maximum speed of 700 km/s and above is a sufficient but not necessary condition for the > 0.8 MeV electron flux to reach 10(exp 5) pfu. But in the exception cases of HSS events where the electron flux level exceeds the 10(exp 5) pfu value but the maximum solar wind speed is less than 700 km/s, a prior impact can be noted either from a CME or a transient SIR within 3-4 days before the arrival of the HSS - stressing the importance of time history. Through superposed epoch analysis and studies providing comparisons with the CME events and the HSS events where the flux level fails to reach the 10(exp 5) pfu, we will present the quantitative assessment of behaviors and relationships of various quantities, such as the time it takes to reach the flux threshold value from the stream interface and its dependence on different physical parameters (e.g., duration of the HSS event, its maximum or average of the solar wind speed, IMF Bz, Kp). The ultimate goal is to apply what is derived to space weather forecasting.
NASA Astrophysics Data System (ADS)
van Ruth, Saskia M.; Buhr, Katja
2004-12-01
The influence of mastication rate on the dynamic release of seven volatile flavour compounds from sunflower oil was evaluated by combined model mouth/proton transfer reaction-mass spectrometry (PTR-MS). Air/oil partition coefficients were measured by static headspace gas chromatography. The dynamic release of the seven volatile flavour compounds from sunflower oil was significantly affected by the compounds' hydrophobicity and the mastication rate employed in the model mouth. The more hydrophobic compounds were released at a higher rate than their hydrophilic counterparts. Increase in mastication rate increased the maximum concentration measured by 36% on average, and the time to reach this maximum by 35% on average. Mastication affected particularly the release of the hydrophilic compounds. The maximum concentration of the compounds correlated significantly with the compounds' air/oil partition coefficients. The initial release rates over the first 15 s were affected by the type of compound, but not by the mastication rate. During the course of release, the proportions of the hydrophilic compounds to the overall flavour mixture in air decreased. The contribution of the hydrophobic compounds increased. Higher mastication rates, however, increased the proportions of the hydrophilic compounds and decreased those of the hydrophobic compounds.
Zanganeh, Saeid; Xu, Yan; Hamby, Carl V; Backer, Marina V; Backer, Joseph M; Zhu, Quing
2013-12-01
To develop an indocyanine green (ICG) tracer with slower clearance kinetics, we explored ICG-encapsulating liposomes (Lip) in three different formulations: untargeted (Lip/ICG), targeted to vascular endothelial growth factor (VEGF) receptors (scVEGF-Lip/ICG) by the receptor-binding moiety single-chain VEGF (scVEGF), or decorated with inactivated scVEGF (inactive-Lip/ICG) that does not bind to VEGF receptors. Experiments were conducted with tumor-bearing mice that were placed in a scattering medium with tumors located at imaging depths of either 1.5 or 2.0 cm. Near-infrared fluorescence diffuse optical tomography that provides depth-resolved spatial distributions of fluorescence in tumor was used for the detection of postinjection fluorescent signals. All liposome-based tracers, as well as free ICG, were injected intravenously into mice in the amounts corresponding to 5 nmol of ICG/mouse, and the kinetics of increase and decrease of fluorescent signals in tumors were monitored. A signal from free ICG reached maximum at 15-min postinjection and then rapidly declined with t1/2 of ~20 min. The signals from untargeted Lip/ICG and inactive-Lip/ICG also reached maximum at 15-min postinjection, however, declined somewhat slower than free ICG with t1/2 of ~30 min. By contrast, a signal from targeted scVEGF-Lip/ICG grew slower than that of all other tracers, reaching maximum at 30-min postinjection and declined much slower than that of other tracers with t1/2 of ~90 min, providing a more extended observation window. Higher scVEGF-Lip/ICG tumor accumulation was further confirmed by the analysis of fluorescence on cryosections of tumors that were harvested from animals at 400 min after injection with different tracers.
Comparison of fan beam, slit-slat and multi-pinhole collimators for molecular breast tomosynthesis.
van Roosmalen, Jarno; Beekman, Freek J; Goorden, Marlies C
2018-05-16
Recently, we proposed and optimized dedicated multi-pinhole molecular breast tomosynthesis (MBT) that images a lightly compressed breast. As MBT may also be performed with other types of collimators, the aim of this paper is to optimize MBT with fan beam and slit-slat collimators and to compare its performance to that of multi-pinhole MBT to arrive at a truly optimized design. Using analytical expressions, we first optimized fan beam and slit-slat collimator parameters to reach maximum sensitivity at a series of given system resolutions. Additionally, we performed full system simulations of a breast phantom containing several tumours for the optimized designs. We found that at equal system resolution the maximum achievable sensitivity increases from pinhole to slit-slat to fan beam collimation with fan beam and slit-slat MBT having on average a 48% and 20% higher sensitivity than multi-pinhole MBT. Furthermore, by inspecting simulated images and applying a tumour-to-background contrast-to-noise (TB-CNR) analysis, we found that slit-slat collimators underperform with respect to the other collimator types. The fan beam collimators obtained a similar TB-CNR as the pinhole collimators, but the optimum was reached at different system resolutions. For fan beam collimators, a 6-8 mm system resolution was optimal in terms of TB-CNR, while with pinhole collimation highest TB-CNR was reached in the 7-10 mm range.
Serum C-reactive protein in patients undergoing elective shoulder arthroplasty. Prospective study.
Torrens, Carlos; Santana, Fernando; Marí, Raquel; Puig, Lluis; Alier, Albert
2017-09-01
The objective of the study was to determine the normalization curve of the serum C-reactive protein (CRP) in elective shoulder arthroplasty. A prospective study including 58 consecutive patients who had undergone elective shoulder arthroplasty. Forty-one patients had received a Reverse Shoulder Arthroplasty, 13 a Total Shoulder Arthroplasty and 4 a Hemiarthroplasty. Based on a pilot study, blood samples to determine CRP values were obtained at baseline (1 h before surgery), on the 1st, 2nd, 6th, 8th and 14th postoperative days. All the patients included presented no postoperative complications during inpatient stay or any re-admission during the three months after surgery. Mean CRP values showed a rapid increase on the 1st postoperative day (7-fold higher than the baseline in cuff tear arthropathy, 11-fold higher in primary osteoarthritis, 1-fold higher in acute fracture) and reached a peak on the 2nd postoperative day (14-fold higher than the baseline in cuff tear arthropathy, 24-fold higher in primary osteoarthritis and 2-fold higher in acute fracture). After the 2nd postoperative day CRP values began to slowly decrease reaching the normal range in the 14th postoperative day. Serum CRP levels after elective shoulder arthroplasty rapidly increase to reach a maximum peak after the 2nd surgery day and then slowly decrease to return to normality on the 14th day. Knowing the normalization curve of CRP can be a helpful tool to help in the diagnosis of acute infections in elective shoulder arthroplasty. Copyright © 2017 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights reserved.
Envelope matching for enhanced backward Raman amplification by using self-ionizing plasmas
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhang, Z. M.; Zhang, B.; Hong, W.
2014-12-15
Backward Raman amplification (BRA) in plasmas has been promoted as a means for generating ultrapowerful laser pulses. For the purpose of achieving the maximum intensities over the shortest distances, an envelope matching between the seed pulse and the amplification gain is required, i.e., the seed pulse propagates at the same velocity with the gain such that the peak of the seed pulse can always enjoy the maximum gain. However, such an envelope matching is absent in traditional BRA because in the latter the amplification gain propagates at superluminous velocity while the seed pulse propagates at the group velocity, which ismore » less than the speed of light. It is shown here that, by using self-ionizing plasmas, the speed of the amplification gain can be well reduced to reach the envelope matching regime. This results in a favorable BRA process, in which higher saturated intensity, shorter interaction length and higher energy-transfer efficiency are achieved.« less
Dynamic push-pull characteristics at three hand-reach envelopes: applications for the workplace.
Calé-Benzoor, Maya; Dickstein, Ruth; Arnon, Michal; Ayalon, Moshe
2016-01-01
Pushing and pulling are common tasks in the workplace. Overexertion injuries related to manual pushing and pulling are often observed, and therefore the understanding of work capacity is important for efficient and safe workstation design. The purpose of the present study was to describe workloads obtained during different reach envelopes during a seated push-pull task. Forty-five women performed an isokinetic push-pull sequence at two velocities. Strength, work and agonist/antagonist muscle ratio were calculated for the full range of motion (ROM). We then divided the ROM into three reach envelopes - neutral, medium, and maximum reach. The work capacity for each direction was determined and the reach envelope work data were compared. Push capability was best at medium reach envelope and pulling was best at maximum reach envelope. Push/pull strength ratio was approximately 1. A recommendation was made to avoid strenuous push-pull tasks at neutral reach envelopes. Copyright © 2015 Elsevier Ltd and The Ergonomics Society. All rights reserved.
Experimental Investigation of the Induced Airflow of Corona Discharge
NASA Astrophysics Data System (ADS)
Huang, Yong; Zhang, Xin; Wang, Xun-Nian; Wang, Wan-Bo; Huang, Zong-Bo; Li, Hua-Xing
2013-09-01
In order to improve the acceleration effect of corona discharge acting on air, we present an experimental study on the induced airflow produced by corona discharge between two parallel electrodes. The parameters investigated are the type of electrodes, actuation voltage and the distance in the absence of free airflow. The induced flow velocity is measured directly in the accelerated region using the particle image velocimetry technology. The results show that if corona discharge is not developed into arc discharge, the induced airflow velocity increases nearly linearly with the applied voltage and the maximum induced airflow velocity near the needle electrode reaches 36 m/s. It is expected that in the future, the result can be referred to in the research about effect of active flow control to reach much higher induced airflow speed.
31 CFR 29.342 - Computed annuity exceeds the statutory maximum.
Code of Federal Regulations, 2011 CFR
2011-07-01
...) In cases in which the total computed annuity exceeds the statutory maximum: (1) Federal Benefit... sufficient service as of June 30, 1997, to reach the statutory maximum benefit, but has sufficient service at...
Wathen, Steve; Thorne, James H.; Holguin, Andrew; Schwartz, Mark W.
2014-01-01
Evidence for significant losses of species richness or biodiversity, even within protected natural areas, is mounting. Managers are increasingly being asked to monitor biodiversity, yet estimating biodiversity is often prohibitively expensive. As a cost-effective option, we estimated the spatial and temporal distribution of species richness for four taxonomic groups (birds, mammals, herpetofauna (reptiles and amphibians), and plants) within Sequoia and Kings Canyon National Parks using only existing biological studies undertaken within the Parks and the Parks' long-term wildlife observation database. We used a rarefaction approach to model species richness for the four taxonomic groups and analyzed those groups by habitat type, elevation zone, and time period. We then mapped the spatial distributions of species richness values for the four taxonomic groups, as well as total species richness, for the Parks. We also estimated changes in species richness for birds, mammals, and herpetofauna since 1980. The modeled patterns of species richness either peaked at mid elevations (mammals, plants, and total species richness) or declined consistently with increasing elevation (herpetofauna and birds). Plants reached maximum species richness values at much higher elevations than did vertebrate taxa, and non-flying mammals reached maximum species richness values at higher elevations than did birds. Alpine plant communities, including sagebrush, had higher species richness values than did subalpine plant communities located below them in elevation. These results are supported by other papers published in the scientific literature. Perhaps reflecting climate change: birds and herpetofauna displayed declines in species richness since 1980 at low and middle elevations and mammals displayed declines in species richness since 1980 at all elevations. PMID:25469873
Exacerbated Glial Response in the Aged Mouse Hippocampus Following Controlled Cortical Impact Injury
Sandhir, Rajat; Onyszchuk, Gregory; Berman, Nancy E. J.
2008-01-01
Old age is associated with enhanced susceptibility to and poor recovery from brain injury. An exacerbated microglial and astrocyte response to brain injury might be involved in poor outcomes observed in the elderly. The present study was therefore designed to quantitate the expression of markers of microglia and astrocyte activation using real-time RT-PCR, immunoblot and immunohistochemical analysis in aging brain in response to brain injury. We examined the hippocampus, a region that undergoes secondary neuron death, in aged (21–24 month) and adult (5–6 month) mice following controlled cortical impact (CCI) injury to the sensorimotor cortex. Basal mRNA expression of CD11b and Iba1, markers of activated microglia, was higher in aged hippocampus as compared to the adult. The mRNA expression of microglial markers increased and reached maximum 3 days post injury in both adult and aged mice, but was higher in the aged mice at all time points studied, and in the aged mice the return to baseline levels was delayed. Basal mRNA expression of GFAP and S100B, markers of activated astrocytes, was higher in aged mice. Both markers increased and reached maximum 7 days post injury. The mRNA expression of astrocyte markers returned to near basal levels rapidly after injury in the adult mice, whereas again in the aged mice return to baseline was delayed. Immunochemical analysis using Iba1 and GFAP antibodies indicate accentuated glial responses in the aged hippocampus after injury. The pronounced and prolonged activation of microglia and astrocytes in hippocampus may contribute to worse cognitive outcomes in the elderly following TBI. PMID:18692046
Tosi, Simone; Costa, Cecilia; Vesco, Umberto; Quaglia, Giancarlo; Guido, Giovanni
2018-02-15
Honey bee (Apis mellifera L.) health is compromised by complex interactions between multiple stressors, among which pesticides play a major role. To better understand the extent of honey bee colonies' exposure to pesticides in time and space, we conducted a survey by collecting corbicular pollen from returning honey bee foragers in 53 Italian apiaries during the active beekeeping season of 3 subsequent years (2012-2014). Of 554 pollen samples analysed for pesticide residues, 62% contained at least one pesticide. The overall rate of multiresidual samples (38%) was higher than the rate of single pesticide samples (24%), reaching a maximum of 7 pesticides per sample (1%). Over 3years, 18 different pesticides were detected (10 fungicides and 8 insecticides) out of 66 analysed. Pesticide concentrations reached the level of concern for bee health (Hazard Quotient (HQ) higher than 1000) at least once in 13% of the apiaries and exceeded the thresholds of safety for human dietary intake (Acute Reference Dose (ARfD), the Acceptable Daily Intake (ADI), and the Maximum Residue Limit (MRL)) in 39% of the analysis. The pesticide which was most frequently detected was the insecticide chlorpyrifos (30% of the samples overall, exceeding ARfD, ADI, or MRL in 99% of the positive ones), followed by the fungicides mandipropamid (19%), metalaxyl (16%), spiroxamine (15%), and the neonicotinoid insecticide imidacloprid (12%). Imidacloprid had also the highest HQ level (5054, with 12% of its positive samples with HQ higher than 1000). This 3year survey provides further insights on the contamination caused by agricultural pesticide use on honey bee colonies. Bee-collected pollen is shown to be a valuable tool for environmental monitoring, and for the detection of illegal uses of pesticides. Copyright © 2017 Elsevier B.V. All rights reserved.
Wathen, Steve; Thorne, James H; Holguin, Andrew; Schwartz, Mark W
2014-01-01
Evidence for significant losses of species richness or biodiversity, even within protected natural areas, is mounting. Managers are increasingly being asked to monitor biodiversity, yet estimating biodiversity is often prohibitively expensive. As a cost-effective option, we estimated the spatial and temporal distribution of species richness for four taxonomic groups (birds, mammals, herpetofauna (reptiles and amphibians), and plants) within Sequoia and Kings Canyon National Parks using only existing biological studies undertaken within the Parks and the Parks' long-term wildlife observation database. We used a rarefaction approach to model species richness for the four taxonomic groups and analyzed those groups by habitat type, elevation zone, and time period. We then mapped the spatial distributions of species richness values for the four taxonomic groups, as well as total species richness, for the Parks. We also estimated changes in species richness for birds, mammals, and herpetofauna since 1980. The modeled patterns of species richness either peaked at mid elevations (mammals, plants, and total species richness) or declined consistently with increasing elevation (herpetofauna and birds). Plants reached maximum species richness values at much higher elevations than did vertebrate taxa, and non-flying mammals reached maximum species richness values at higher elevations than did birds. Alpine plant communities, including sagebrush, had higher species richness values than did subalpine plant communities located below them in elevation. These results are supported by other papers published in the scientific literature. Perhaps reflecting climate change: birds and herpetofauna displayed declines in species richness since 1980 at low and middle elevations and mammals displayed declines in species richness since 1980 at all elevations.
Papathanasiou, George; Georgakopoulos, Dimitris; Papageorgiou, Effie; Zerva, Efthimia; Michalis, Lampros; Kalfakakou, Vasiliki; Evangelou, Angelos
2013-01-01
There is an established link between smoking, abnormal heart rate (HR) values, and impaired cardiovascular health in middle-aged or older populations. The purpose of this study was to examine the effects of smoking on resting HR and on HR responses during and after exercise in young adults. A sample of 298 young adults (159 men), aged 20-29 years old, were selected from a large population of health-science students based on health status, body mass index, physical activity, and smoking habit. All subjects underwent a maximal Bruce treadmill test and their HR was recorded during, at peak, and after termination of exercise. Smokers had significantly higher resting HR values than non-smokers. Both female and male smokers showed a significantly slower HR increase during exercise. Female smokers failed to reach their age-predicted maximum HR by 6.0 bpm and males by 3.6 bpm. The actual maximum HR achieved (HRmax) was significantly lower for both female smokers (191.0 bpm vs.198.0 bpm) and male smokers (193.2 bpm vs.199.3 bpm), compared to non-smokers. Heart rate reserve was also significantly lower in female (114.6 bpm vs. 128.1 bpm) and male smokers (120.4 bpm vs. 133.0 bpm). During recovery, the HR decline was significantly attenuated, but only in female smokers. Females had a higher resting HR and showed a higher HR response during sub-maximal exercise compared to males. Smoking was found to affect young smokers' HR, increasing HR at rest, slowing HR increase during exercise and impairing their ability to reach the age-predicted HRmax. In addition, smoking was associated with an attenuated HR decline during recovery, but only in females.
Backwater effects in the Amazon River basin of Brazil
Meade, R.H.; Rayol, J.M.; Da Conceicao, S.C.; Natividade, J.R.G.
1991-01-01
The Amazon River mainstem of Brazil is so regulated by differences in the timing of tributary inputs and by seasonal storage of water on floodplains that maximum discharges exceed minimum discharges by a factor of only 3. Large tributaries that drain the southern Amazon River basin reach their peak discharges two months earlier than does the mainstem. The resulting backwater in the lowermost 800 km of two large southern tributaries, the Madeira and Puru??s rivers, causes falling river stages to be as much as 2-3 m higher than rising stages at any given discharge. Large tributaries that drain the northernmost Amazon River basin reach their annual minimum discharges three to four months later than does the mainstem. In the lowermost 300-400 km of the Negro River, the largest northern tributary and the fifth largest river in the world, the lowest stages of the year correspond to those of the Amazon River mainstem rather than to those in the upstream reaches of the Negro River. ?? 1991 Springer-Verlag New York Inc.
Ahn, Junho; Choi, Yeonweon; Lee, Ae-Ree; Lee, Joon-Hwa; Jung, Jong Hwa
2016-03-21
Using duplex DNA-AuNP aggregates, a sequence-specific DNA-binding protein, SQUAMOSA Promoter-binding-Like protein 12 (SPL-12), was directly determined by SPL-12-duplex DNA interaction-based colorimetric actions of DNA-Au assemblies. In order to prepare duplex DNA-Au aggregates, thiol-modified DNA 1 and DNA 2 were attached onto the surface of AuNPs, respectively, by the salt-aging method and then the DNA-attached AuNPs were mixed. Duplex-DNA-Au aggregates having the average size of 160 nm diameter and the maximum absorption at 529 nm were able to recognize SPL-12 and reached the equivalent state by the addition of ∼30 equivalents of SPL-12 accompanying a color change from red to blue with a red shift of the maximum absorption at 570 nm. As a result, the aggregation size grew to about 247 nm. Also, at higher temperatures of the mixture of duplex-DNA-Au aggregate solution and SPL-12, the equivalent state was reached rapidly. On the contrary, in the control experiment using Bovine Serum Albumin (BSA), no absorption band shift of duplex-DNA-Au aggregates was observed.
Radioactivities vs. depth in Apollo 16 and 17 soil
NASA Technical Reports Server (NTRS)
Fireman, E. L.; D'Amico, J.; Defelice, J.
1973-01-01
The radioactivities of Ar-37, Ar-39, and H-3 measured at a number of depths for Apollo 16 and 17 soil are reported. The Ar-37 activities vs depth in the Apollo 16 drill string increased with depth and reached a broad maximum in the neighborhood of 50 g per sq cm before decreasing. The Ar-39 activities in Apollo 17 soil were higher than in Apollo 16 soil, probably owing to the higher Fe and Ti contents. The H-3 activities in Apollo 16 and 17 soil were quite similar and indicate that the 4 August 1972 flare produced very little H-3 compared to the amount produced by solar flares during the previous 50 years.
Lima, Filipe S; Cuccovia, Iolanda M; Buchner, Richard; Antunes, Filipe E; Lindman, Björn; Miguel, Maria G; Horinek, Dominik; Chaimovich, Hernan
2015-03-10
Dodecyltrimethylammonium triflate (DTATf) micelles possess lower degree of counterion dissociation (α), lower hydration, and higher packing of monomers than other micelles of similar structure. Addition of sodium triflate ([NaTf] > 0.05 M) to DTATf solutions promotes phase separation. This phenomenon is commonly observed in oppositely charged surfactant mixtures, but it is rare for ionic surfactants and relatively simple counterions. While the properties of DTATf have already been reported, the driving forces for the observed phase separation with added salt remain unclear. Thus, we propose an interpretation for the observed phase separation in cationic surfactant solutions. Addition of up to 0.03 M NaTf to micellar DTATf solutions led to a limited increase of the aggregation number, to interface dehydration, and to a progressive decrease in α. The viscosity of DTATf solutions of higher concentration ([DTATf] ≥ 0.06 M) reached a maximum with increasing [NaTf], though the aggregation number slightly increased, and no shape change occurred. We hypothesize that this maximum results from a decrease in interaggregate repulsion, as a consequence of increased ion binding. This reduction in micellar repulsion without simultaneous infinite micellar growth is, probably, the major driving force for phase separation at higher [NaTf].
Restoring Maximum Vertical Browsing Reach in Sauropod Dinosaurs.
Paul, Gregory S
2017-10-01
The ongoing controversy centered on neck posture and function in sauropod dinosaurs is misplaced for a number of reasons. Because of an absence of pertinent data it is not possible to accurately restore the posture and range of motion in long necked fossil animals, only gross approximations are possible. The existence of a single "neutral posture" in animals with long, slender necks may not exist, and its relationship to feeding habits is weak. Restorations of neutral osteological neck posture based on seemingly detailed diagrams of cervical articulations are not reliable because the pictures are not sufficiently accurate due to a combination of illustration errors, and distortion of the fossil cervicals. This is all the more true because fossil cervical series lack the critical inter-centra cartilage. Maximum vertical reach is more readily restorable and biologically informative for long necked herbivores. Modest extension of 10° between each caudal cervical allowed high shouldered sauropods to raise the cranial portion of their necks to vertical postures that allowed them to reach floral resources far higher than seen in the tallest mammals. This hypothesis is supported by the dorsally extended articulation of the only known co-fused sauropod cervicals. Many sauropods appear to have been well adapted for rearing in order to boost vertical reach, some possessed retroverted pelves that may have allowed them to walk slowly while bipedal. A combination of improved high browsing abilities and sexual selection probably explains the unusually long necks of tall ungulates and super tall sauropods. Anat Rec, 2017. © 2017 Wiley Periodicals, Inc. Anat Rec, 300:1802-1825, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.
García-Sánchez, Marta; Korbee, Nathalie; Pérez-Ruzafa, Isabel María; Marcos, Concepción; Figueroa, Félix L; Pérez-Ruzafa, Ángel
2014-10-01
The physiological status of Cystoseira compressa, Padina pavonica and Palisada tenerrima was studied by in vivo chlorophyll fluorescence, pigment content, stoichiometry (C:N), accumulation of UV photoprotectors and antioxidant activity; comparing their photosynthetic response in a coastal lagoon (Mar Menor) and in Mediterranean coastal waters. In general, the specimens reached their highest ETRmax in spring in the Lagoon, but in summer in the Mediterranean, coinciding with their maximum biomass peak. The species exhibited a dynamic photoinhibition. Except C. compressa, they showed a lower decrease in Fv/Fm and higher recovery rates in the Mediterranean populations when exposed to high irradiance. The higher salinity and temperature of the lagoon could impair the photoprotection mechanisms. The acclimation to lagoon environments is species-specific and involves complex regulatory mechanisms. The results underline the importance of N in repair, avoidance, quenching and scavenging mechanisms. In general, Lagoon specimens showed higher pigment concentration. Although xanthophylls play important photo-protective and antioxidant roles, the observed trend is more likely to be explained by the higher temperatures reached in the lagoon compared to Mediterranean. Therefore the studied photosynthetic and biochemical mechanisms can be effective not only for high irradiance, but also for higher temperatures in a climate change scenario, but are highly dependent on nutrient availability. Copyright © 2014 Elsevier Ltd. All rights reserved.
NASA Technical Reports Server (NTRS)
Lindsey, Patricia F.
1994-01-01
In microgravity conditions mobility is greatly enhanced and body stability is difficult to achieve. Because of these difficulties, optimum placement and accessibility of objects and controls can be critical to required tasks on board shuttle flights or on the proposed space station. Anthropometric measurement of the maximum reach of occupants of a microgravity environment provide knowledge about maximum functional placement for tasking situations. Calculations for a full body, functional reach envelope for microgravity environments are imperative. To this end, three dimensional computer modeled human figures, providing a method of anthropometric measurement, were used to locate the data points that define the full body, functional reach envelope. Virtual reality technology was utilized to enable an occupant of the microgravity environment to experience movement within the reach envelope while immersed in a simulated microgravity environment.
NASA Astrophysics Data System (ADS)
Henry, A.; Bezrukova, E. V.; Teten'kin, A. V.; Kuz'min, M. I.
2018-02-01
The first results of anthracological investigation for Eastern Siberia on the carbonaceous remains of woody and shrubby plants at the archaeological sites Kovrizhka III and IV in the lower reaches of the Vitim River are presented. The results of anthracological studies enabled us to obtain new data on changes in vegetation and climate along the lower reaches of the Vitim River. As a result, new data on human habitation in the lower reaches of the Vitim River in the last glacial maximum and early Holocene were obtained.
Comparison of fan beam, slit-slat and multi-pinhole collimators for molecular breast tomosynthesis
NASA Astrophysics Data System (ADS)
van Roosmalen, Jarno; Beekman, Freek J.; Goorden, Marlies C.
2018-05-01
Recently, we proposed and optimized dedicated multi-pinhole molecular breast tomosynthesis (MBT) that images a lightly compressed breast. As MBT may also be performed with other types of collimators, the aim of this paper is to optimize MBT with fan beam and slit-slat collimators and to compare its performance to that of multi-pinhole MBT to arrive at a truly optimized design. Using analytical expressions, we first optimized fan beam and slit-slat collimator parameters to reach maximum sensitivity at a series of given system resolutions. Additionally, we performed full system simulations of a breast phantom containing several tumours for the optimized designs. We found that at equal system resolution the maximum achievable sensitivity increases from pinhole to slit-slat to fan beam collimation with fan beam and slit-slat MBT having on average a 48% and 20% higher sensitivity than multi-pinhole MBT. Furthermore, by inspecting simulated images and applying a tumour-to-background contrast-to-noise (TB-CNR) analysis, we found that slit-slat collimators underperform with respect to the other collimator types. The fan beam collimators obtained a similar TB-CNR as the pinhole collimators, but the optimum was reached at different system resolutions. For fan beam collimators, a 6–8 mm system resolution was optimal in terms of TB-CNR, while with pinhole collimation highest TB-CNR was reached in the 7–10 mm range.
Smith, Eric Krabbe; O'Neill, Jacqueline J; Gerson, Alexander R; McKechnie, Andrew E; Wolf, Blair O
2017-09-15
We examined thermoregulatory performance in seven Sonoran Desert passerine bird species varying in body mass from 10 to 70 g - lesser goldfinch, house finch, pyrrhuloxia, cactus wren, northern cardinal, Abert's towhee and curve-billed thrasher. Using flow-through respirometry, we measured daytime resting metabolism, evaporative water loss and body temperature at air temperatures ( T air ) between 30 and 52°C. We found marked increases in resting metabolism above the upper critical temperature ( T uc ), which for six of the seven species fell within a relatively narrow range (36.2-39.7°C), but which was considerably higher in the largest species, the curve-billed thrasher (42.6°C). Resting metabolism and evaporative water loss were minimal below the T uc and increased with T air and body mass to maximum values among species of 0.38-1.62 W and 0.87-4.02 g H 2 O h -1 , respectively. Body temperature reached maximum values ranging from 43.5 to 45.3°C. Evaporative cooling capacity, the ratio of evaporative heat loss to metabolic heat production, reached maximum values ranging from 1.39 to 2.06, consistent with known values for passeriforms and much lower than values in taxa such as columbiforms and caprimulgiforms. These maximum values occurred at heat tolerance limits that did not scale with body mass among species, but were ∼50°C for all species except the pyrrhuloxia and Abert's towhee (48°C). High metabolic costs associated with respiratory evaporation appeared to drive the limited heat tolerance in these desert passeriforms, compared with larger desert columbiforms and galliforms that use metabolically more efficient mechanisms of evaporative heat loss. © 2017. Published by The Company of Biologists Ltd.
Multi-watt passively Q-switched Yb:YAB/Cr:YAG microchip lasers
NASA Astrophysics Data System (ADS)
Serres, Josep Maria; Loiko, Pavel; Mateos, Xavier; Liu, Junhai; Zhang, Huaijing; Yumashev, Konstantin; Griebner, Uwe; Petrov, Valentin; Aguiló, Magdalena; Díaz, Francesc
2017-02-01
A trigonal 5.6 at.% Yb:YAl3(BO3)4 (Yb:YAB) crystal is employed in continuous-wave (CW) and passively Q-switched microchip lasers pumped by a diode at 978 nm. Using a 3 mm-thick, c-cut Yb:YAB crystal, which has a higher pump absorption efficiency, efficient CW microchip laser operation is demonstrated. This laser generated a maximum output power of 7.18 W at 1041-1044 nm with a slope efficiency η of 67% (with respect to the absorbed pump power) and an almost diffraction-limited beam, M2 x,y < 1.1. Inserting a Cr:YAG saturable absorber, stable passive Q-switching of the Yb:YAB microchip laser was obtained. The maximum average output power from the Yb:YAB/Cr:YAG laser reached 2.82 W at 1042 nm with η = 53% and a conversion efficiency with respect to the CW mode of 65% (when using a 0.7 mm-thick Cr:YAG). The latter corresponded to a pulse duration and energy of 7.1 ns / 47 μJ at a pulse repetition rate (PRR) of 60 kHz. Using a 1.3 mm-thick Cr:YAG, 2.02 W were achieved at 1041 nm corresponding to η = 38%. The pulse characteristics were 4.9 ns / 83 μJ at PRR = 24.3 kHz and the maximum peak power reached 17 kW. Yb:YAB crystals are very promising for compact sub-ns power-scalable microchip lasers.
Children's Visual Processing of Egocentric Cues in Action Planning for Reach
ERIC Educational Resources Information Center
Cordova, Alberto; Gabbard, Carl
2011-01-01
In this study the authors examined children's ability to code visual information into an egocentric frame of reference for planning reach movements. Children and adults estimated reach distance via motor imagery in immediate and response-delay conditions. Actual maximum reach was compared to estimates in multiple locations in peripersonal and…
Noise pollution in intensive care units and emergency wards.
Khademi, Gholamreza; Roudi, Masoumeh; Shah Farhat, Ahmad; Shahabian, Masoud
2011-01-01
The improvement of technology has increased noise levels in hospital Wards to higher than international standard levels (35-45 dB). Higher noise levels than the maximum level result in patient's instability and dissatisfaction. Moreover, it will have serious negative effects on the staff's health and the quality of their services. The purpose of this survey is to analyze the level of noise in intensive care units and emergency wards of the Imam Reza Teaching Hospital, Mashhad. This research was carried out in November 2009 during morning shifts between 7:30 to 12:00. Noise levels were measured 10 times at 30-minute intervals in the nursing stations of 10 wards of the emergency, the intensive care units, and the Nephrology and Kidney Transplant Departments of Imam Reza University Hospital, Mashhad. The noise level in the nursing stations was tested for both the maximum level (Lmax) and the equalizing level (Leq). The research was based on the comparison of equalizing levels (Leq) because maximum levels were unstable. In our survey the average level (Leq) in all wards was much higher than the standard level. The maximum level (Lmax) in most wards was 85-86 dB and just in one measurement in the Internal ICU reached 94 dB. The average level of Leq in all wards was 60.2 dB. In emergency units, it was 62.2 dB, but it was not time related. The highest average level (Leq) was measured at 11:30 AM and the peak was measured in the Nephrology nursing station. The average levels of noise in intensive care units and also emergency wards were more than the standard levels and as it is known these wards have vital roles in treatment procedures, so more attention is needed in this area.
Thermal Skin Damage During Reirradiation and Hyperthermia Is Time-Temperature Dependent
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bakker, Akke, E-mail: akke.bakker@amc.uva.nl; Kolff, M. Willemijn; Holman, Rebecca
Purpose: To investigate the relationship of thermal skin damage (TSD) to time–temperature isoeffect levels for patients with breast cancer recurrence treated with reirradiation plus hyperthermia (reRT + HT), and to investigate whether the treatment history of previous treatments (scar tissue) is a risk factor for TSD. Methods and Materials: In this observational study, temperature characteristics of hyperthermia sessions were analyzed in 262 patients with recurrent breast cancer treated in the AMC between 2010 and 2014 with reirradiation and weekly hyperthermia for 1 hour. Skin temperature was measured using a median of 42 (range, 29-82) measurement points per hyperthermia session. Results: Sixty-eight patients (26%) developed 79more » sites of TSD, after the first (n=26), second (n=17), third (n=27), and fourth (n=9) hyperthermia session. Seventy percent of TSD occurred on or near scar tissue. Scar tissue reached higher temperatures than other skin tissue (0.4°C, P<.001). A total of 102 measurement points corresponded to actual TSD sites in 35 of 79 sessions in which TSD developed. Thermal skin damage sites had much higher maximum temperatures than non-TSD sites (2.8°C, P<.001). Generalized linear mixed models showed that the probability of TSD is related to temperature and thermal dose values (P<.001) and that scar tissue is more at risk (odds ratio 0.4, P<.001). Limiting the maximum temperature of a measurement point to 43.7°C would mean that the probability of observing TSD was at most 5%. Conclusion: Thermal skin damage during reRT + HT for recurrent breast cancer was related to higher local temperatures and time–temperature isoeffect levels. Scar tissue reached higher temperatures than other skin tissue, and TSD occurred at lower temperatures and thermal dose values in scar tissue compared with other skin tissue. Indeed, TSD developed often on and around scar tissue from previous surgical procedures.« less
Differential uptake of salicylate in serum, cerebrospinal fluid, and perilymph.
Jastreboff, P J; Hansen, R; Sasaki, P G; Sasaki, C T
1986-10-01
After intraperitoneal administration of salicylate in anesthetized rats and guinea pigs, we found that salicylate levels in perilymph (PL) are closely related to both drug levels in cerebrospinal fluid (CSF) and in serum, with higher levels systematically observed in PL than in CSF. Further analysis suggests that salicylate is not passively transported into PL across CSF but, rather, is transported from blood directly to PL. The time course of salicylate uptake in rats reveals maximum levels at 1 1/2 hours (serum) and two to four hours (CSF and PL). On the other hand, salicylate uptake into serum and CSF of guinea pigs exhibits a longer time course, with maximum levels reached at four hours (serum) and five hours (CSF). These data, not previously available, are basic to our understanding of salicylate-related auditory effects.
Formic acid production using a microbial electrolysis desalination and chemical-production cell.
Lu, Yaobin; Luo, Haiping; Yang, Kunpeng; Liu, Guangli; Zhang, Renduo; Li, Xiao; Ye, Bo
2017-11-01
The aim of this study was to investigate the feasibility and optimization of formic acid production in the microbial electrolysis desalination and chemical-production cell (MEDCC). The maximum current density in the MEDCC with 72cm of the anode fiber length (72-MEDCC) reached 24.0±2.0A/m 2 , which was much higher than previously reported. The maximum average formic acid production rate in the 72-MEDCC was 5.28 times higher than that in the MEDCC with 24cm of the anode fiber length (37.00±1.15vs. 7.00±0.25mg/h). High performance in the 72-MEDCC was attributed to small membrane spacing (1mm), high flow rate (1500μL/min) on the membrane surface and high anode biomass. The minimum electricity consumption of 0.34±0.04kWh/kg in the 72-MEDCC was only 3.1-18.8% of those in the EDBMs. The MEDCC should be a promising technology for the formic acid production. Copyright © 2017 Elsevier Ltd. All rights reserved.
Mapping benthic macroalgal communities in the coastal zone using CHRIS-PROBA mode 2 images
NASA Astrophysics Data System (ADS)
Casal, G.; Kutser, T.; Domínguez-Gómez, J. A.; Sánchez-Carnero, N.; Freire, J.
2011-09-01
The ecological importance of benthic macroalgal communities in coastal ecosystems has been recognised worldwide and the application of remote sensing to study these communities presents certain advantages respect to in situ methods. The present study used three CHRIS-PROBA images to analyse macroalgal communities distribution in the Seno de Corcubión (NW Spain). The use of this sensor represent a challenge given that its design, build and deployment programme is intended to follow the principles of the "faster, better, cheaper". To assess the application of this sensor to macroalgal mapping, two types of classifications were carried out: Maximum Likelihood and Spectral Angle Mapper (SAM). Maximum Likelihood classifier showed positive results, reaching overall accuracy percentages higher than 90% and kappa coefficients higher than 0.80 for the bottom classes shallow submerged sand, deep submerged sand, macroalgae less than 5 m and macroalgae between 5 and 10 m depth. The differentiation among macroalgal groups using SAM classifications showed positive results for green seaweeds although the differentiation between brown and red algae was not clear in the study area.
Obliquely Incident Solitary Wave onto a Vertical Wall
NASA Astrophysics Data System (ADS)
Yeh, Harry
2012-10-01
When a solitary wave impinges obliquely onto a reflective vertical wall, it can take the formation of a Mach reflection (a geometrically similar reflection from acoustics). The mathematical theory predicts that the wave at the reflection can amplify not twice, but as high as four times the incident wave amplitude. Nevertheless, this theoretical four-fold amplification has not been verified by numerical or laboratory experiments. We discuss the discrepancies between the theory and the experiments; then, improve the theory with higher-order corrections. The modified theory results in substantial improvement and is now in good agreement with the numerical as well as our laboratory results. Our laboratory experiments indicate that the wave amplitude along the reflective wall can reach 0.91 times the quiescent water depth, which is higher than the maximum of a freely propagating solitary wave. Hence, this maximum runup 0.91 h would be possible even if the amplitude of the incident solitary wave were as small as 0.24 h. This wave behavior could provide an explanation for local variability of tsunami runup as well as for sneaker waves.
High time resolution measurements of rocket potential changes induced by electron beam emission
NASA Technical Reports Server (NTRS)
Raitt, W. J.; Myers, N. B.; Williamson, P. R.; Banks, P. M.; Kawashima, N.
1984-01-01
The transient charging and photon emission from the vacuum chamber testing of the Cooperative High Altitude Rocket Gun Experiment are studied. Graphs of the mother-daughter voltage versus time and high time resolution data related to the return current to the vehicle are examined. It is observed that for average sounding rocket densities of 10 to the -6th torr the slope of the voltage rise of the rocket begins to flatten 40 microsec after the onset of electron beam emission, and for higher gas pressure the rocket reaches a maximum voltage of 25 or 30 microsec after the onset of electron beam emission. The data reveal that the return current mechanism for the higher gas pressure is through the sheath.
Jung, Christian; Ferrari, Markus; Goebel, Bjoern; Figulla, Hans R
2009-08-21
The exercise electrocardiogram is a commonly used non-invasive method for detection of electrocardiogram (ECG) changes secondary to myocardial ischemia. Studies showed the importance of the patient's motivation to reach the estimated submaximal heart rate. The purpose of this study was to test whether the patient's motivation is dependent on the investigator's sex. We included 1170 patients (in-hospital patients and out-clinic patients; 63.5% male, 36.5% female) in this study. Stress test data (stationary bicycle with gradually increasing intensity) were collected retrospectively: patient's age, sex, maximal power stage, ECG-abnormalities, angina pectoris, and attending physician's sex. Male patients achieved a higher power stage than their female counterparts (126.5+/-47.7 W vs. 89.7+/-30.4 W). When male patients were supervised by a female doctor they reached higher maximum power stages (136.6+/-53.5 W vs. 121.6+/-43.3 W; p=0,001), more often the submaximal heart rate (47.9% vs. 38.3%; p=0.02) but complained less frequent about angina pectoris (5.6% vs. 17.3%). In contrast, none of these parameters was dependent on the attending physician's sex in female patients. The attending physician's sex influences the maximum exercise ability and the incidence of complaints during bicycle stress in male patients but not in females. We would speculate that men try to impress women with physical strength and try to dissimulate physical discomfort or pain. This could possibly influence the validity of such non-invasive methods with exercise dependent detection of myocardial ischemia.
ERIC Educational Resources Information Center
Ramenzoni, Veronica; Riley, Michael A.; Davis, Tehran; Shockley, Kevin; Armstrong, Rachel
2008-01-01
Three experiments investigated the ability to perceive the maximum height to which another actor could jump to reach an object. Experiment 1 determined the accuracy of estimates for another actor's maximal reach-with-jump height and compared these estimates to estimates of the actor's standing maximal reaching height and to estimates of the…
Vladislav Gulis; Keller Suberkropp
2003-01-01
1. Decomposition of red maple (Acer rubrum) and rhododendron (Rhododendron maximum) leaves and activity of associated microorganisms were compared in two reaches of a headwater stream in Coweeta Hydrologic Laboratory, NC, U.S.A. The downstream reach was enriched with ammonium, nitrate, and phosphate whereas the upstream reach was not altered.2. Decomposition...
Noakes, Matthew J; Wolf, Blair O; McKechnie, Andrew E
2016-03-01
Intraspecific variation in avian thermoregulatory responses to heat stress has received little attention, despite increasing evidence that endothermic animals show considerable physiological variation among populations. We investigated seasonal (summer versus winter) variation in heat tolerance and evaporative cooling in an Afrotropical ploceid passerine, the white-browed sparrow-weaver (Plocepasser mahali; ∼ 47 g) at three sites along a climatic gradient with more than 10 °C variation in mid-summer maximum air temperature (Ta). We measured resting metabolic rate (RMR) and total evaporative water loss (TEWL) using open flow-through respirometry, and core body temperature (Tb) using passive integrated transponder tags. Sparrow-weavers were exposed to a ramped profile of progressively higher Ta between 30 and 52 °C to elicit maximum evaporative cooling capacity (N=10 per site per season); the maximum Ta birds tolerated before the onset of severe hyperthermia (Tb ≈ 44 °C) was considered to be their hyperthermia threshold Ta (Ta,HT). Our data reveal significant seasonal acclimatisation of heat tolerance, with a desert population of sparrow-weavers reaching significantly higher Ta in summer (49.5 ± 1.4 °C, i.e. higher Ta,HT) than in winter (46.8 ± 0.9 °C), reflecting enhanced evaporative cooling during summer. Moreover, desert sparrow-weavers had significantly higher heat tolerance and evaporative cooling capacity during summer compared with populations from more mesic sites (Ta,HT=47.3 ± 1.5 and 47.6 ± 1.3 °C). A better understanding of the contributions of local adaptation versus phenotypic plasticity to intraspecific variation in avian heat tolerance and evaporative cooling capacity is needed for modelling species' responses to changing climates. © 2016. Published by The Company of Biologists Ltd.
Prolonged incubation and stacked film exposure improve sensitivity in western blotting.
Luo, Haitao; Rankin, Gary O; Straley, Shannon; Chen, Yi Charlie
2011-01-01
Western blotting is a basic technique for protein detection. For proteins of less abundance or antibodies of poorer quality, an increased sensitivity is often desired. Although it is commonly known that higher concentrations of antibodies and prolonged film exposure times will help improve sensitivity in western blots, both measures come with their own risks, and it is often unclear to which extent these measures should be applied. We conducted time-course studies to investigate protein-antibody interactions and primary antibody-secondary antibody interactions in western blotting. We also propose a protocol of stacked film exposure and have tested it in standard curves and cancer cell samples. Our study found that protein-primary antibody interactions and primary antibody-secondary antibody interactions could take a longer time than commonly used "one hour" or "overnight", and in some cases longer than 48h, to reach its maximum binding. We also show that the modified protocol of stacked film exposure works well for both standard curves and biological samples, reaching a maximum sensitivity in western blots without blurring target signals or increasing backgrounds. In addition to regular optimization of antibody concentrations and film exposure time, a prolonged incubation with antibodies and stacked film exposure will also help improve sensitivity and reduce background in western blotting. Copyright © 2011 Elsevier Inc. All rights reserved.
Sale, Patrizio; Franceschini, Marco
2014-01-01
The clinical impact of action observation (AO) on upper limb functional recovery in subacute stroke patients is recent evidence. We sought to test the hypothesis that training everyday life activities through AO coupled with task execution might activate the left hemisphere different from the right one. Sixty-seven first-ever ischemic stroke subjects were randomly assigned to receive upper limb training coupled with AO tasks or standard rehabilitation. The groups were matched by age and gender, Bamford category, and interval from stroke and lesion side. Fugl-Meyer (FM) and Box and Block Test (BBT) were used to measure hand function recovery at the end (T1) and 4-5 months after the treatment (T2). At T1, FM was increased by 31% (±26%), of maximum achievable recovery, whereas BBT was increased by 17% (±18%); at T2, FM had reached 43% (±45%) of maximum recovery, while BBT had reached 25% (±22%). Combining the effects of treatment to those of lesion side revealed significantly higher gains, in both FM and BBT scores, in left hemiparetic subjects when exposed to AO as compared to standard rehabilitation alone (P < .01). The findings lead to recommend the use of AO in addition to motor training in left hemiparetic patients. PMID:24967372
Ruiz, J; Arbib, Z; Alvarez-Díaz, P D; Garrido-Pérez, C; Barragán, J; Perales, J A
2014-05-20
This work was aimed at studying the effect of light-darkness and high-low biomass concentrations in the feasibility of removing nitrogen and phosphorus from urban treated wastewater by the microalga Scenedesmus obliquus. Laboratory experiments were conducted in batch, where microalgae were cultured under different initial biomass concentrations (150 and 1500mgSSl(-1)) and light conditions (dark or illuminated). Nutrient uptake was more dependent on internal nutrient content of the biomass than on light presence or biomass concentration. When a maximum nitrogen or phosphorus content in the biomass was reached (around 8% and 2%, respectively), the removal of that nutrient was almost stopped. Biomass concentration affected more than light presence on the nutrient removal rate, increasing significantly with its increase. Light was only required to remove nutrients when the maximum nutrient storage capacity of the cells was reached and further growth was therefore needed. Residence times to maintain a stable biomass concentration, avoiding the washout of the reactor, were much higher than those needed to remove the nutrients from the wastewater. This ability to remove nutrients in the absence of light could lead to new configurations of reactors aimed to wastewater treatment. Copyright © 2014 Elsevier B.V. All rights reserved.
NASA Astrophysics Data System (ADS)
Li, Zhi-jie; Wang, Xiao-er; Li, Jia-yang; Li, Jia; Wang, Hong-zhi
2017-11-01
In order to improve the magnetic properties and corrosion resistance of sintered Nd-Fe-B magnets, the (PrNd)29.9Dy0.1B1Co1Cu0.15Febal (wt%) powders were mixed with Mg nanopowders, as grain boundary modifiers. For Nd-Fe-B magnets with 0.1-0.4 wt% Mg addition, the result showed that addition amount of 0.1 wt% Mg, Hcj reaches the maximum value of 999.1 kA/m, Br reaches 1.436T, (BH)max reaches 396.9 kJ/m3 and magnet density is 7.42 g/cm3, which are related to the microstructural modification of grain boundaries and the magnet density. Effects of Mg addition on corrosion behavior in sulphuric acid and sodium chloride solution were researched by electrochemical workstation. With increase of Mg addition level, the magnet turns to have a higher corrosion potential and lower corrosion current density, the corrosion poverty is improved. However, temperature coefficient remained nearly unchanged with Mg addition.
Wang, Jue; Xie, Fang; Cao, Xuan-Hao; An, Si-Cong; Zhou, Wu-Xing; Tang, Li-Ming; Chen, Ke-Qiu
2017-01-25
By using first-principles calculations combined with the nonequilibrium Green's function method and phonon Boltzmann transport equation, we systematically investigate the influence of chirality, temperature and size on the thermoelectric properties of monolayer WSe 2 nanoribbons. The results show that the armchair WSe 2 nanoribbons have much higher ZT values than zigzag WSe 2 nanoribbons. The ZT values of armchair WSe 2 nanoribbons can reach 1.4 at room temperature, which is about seven times greater than that of zigzag WSe 2 nanoribbons. We also find that the ZT values of WSe 2 nanoribbons increase first and then decrease with the increase of temperature, and reach a maximum value of 2.14 at temperature of 500 K. It is because the total thermal conductance reaches the minimum value at 500 K. Moreover, the impact of width on the thermoelectric properties in WSe 2 nanoribbons is not obvious, the overall trend of ZT value decreases lightly with the increasing temperature. This trend of ZT value originates from the almost constant power factor and growing phonon thermal conductance.
Hsu, Guoo-Shyng Wang; Lu, Yi-Fa; Hsu, Shun-Yao
2017-10-01
Electrolyzed water is a sustainable disinfectant, which can comply with food safety regulations and is environmentally friendly. A two-factor central composite design was adopted for studying the effects of electrolysis time and electric potential on the chlorine generation efficiency of electrolyzed deep ocean water (DOW). DOW was electrolyzed in a glass electrolyzing cell equipped with platinum-plated titanium anode and cathode. The results showed that chlorine concentration reached maximal level in the batch process. Prolonged electrolysis reduced chlorine concentration in the electrolyte and was detrimental to electrolysis efficiency, especially under high electric potential conditions. Therefore, the optimal choice of electrolysis time depends on the electrolyzable chloride in DOW and cell potential adopted for electrolysis. The higher the electric potential, the faster the chlorine level reaches its maximum, but the lower the electric efficiency will be. Copyright © 2016. Published by Elsevier B.V.
Unknown loads affect force production capacity in early phases of bench press throws.
Hernández Davó, J L; Sabido Solana, R; Sarabia Marínm, J M; Sánchez Martos, Á; Moya Ramón, M
2015-10-01
Explosive strength training aims to improve force generation in early phases of movement due to its importance in sport performance. The present study examined the influence of lack of knowledge about the load lifted in explosive parameters during bench press throws. Thirteen healthy young men (22.8±2.0 years) participated in the study. Participants performed bench press throws with three different loads (30, 50 and 70% of 1 repetition maximum) in two different conditions (known and unknown loads). In unknown condition, loads were changed within sets in each repetition and participants did not know the load, whereas in known condition the load did not change within sets and participants had knowledge about the load lifted. Results of repeated-measures ANOVA revealed that unknown conditions involves higher power in the first 30, 50, 100 and 150 ms with the three loads, higher values of ratio of force development in those first instants, and differences in time to reach maximal rate of force development with 50 and 70% of 1 repetition maximum. This study showed that unknown conditions elicit higher values of explosive parameters in early phases of bench press throws, thereby this kind of methodology could be considered in explosive strength training.
Drag reduction and thrust generation by tangential surface motion in flow past a cylinder
NASA Astrophysics Data System (ADS)
Mao, Xuerui; Pearson, Emily
2018-03-01
Sensitivity of drag to tangential surface motion is calculated in flow past a circular cylinder in both two- and three-dimensional conditions at Reynolds number Re ≤ 1000 . The magnitude of the sensitivity maximises in the region slightly upstream of the separation points where the contour lines of spanwise vorticity are normal to the cylinder surface. A control to reduce drag can be obtained by (negatively) scaling the sensitivity. The high correlation of sensitivities of controlled and uncontrolled flow indicates that the scaled sensitivity is a good approximation of the nonlinear optimal control. It is validated through direct numerical simulations that the linear range of the steady control is much higher than the unsteady control, which synchronises the vortex shedding and induces lock-in effects. The steady control injects angular momentum into the separating boundary layer, stabilises the flow and increases the base pressure significantly. At Re=100 , when the maximum tangential motion reaches 50% of the free-stream velocity, the vortex shedding, boundary-layer separation and recirculation bubbles are eliminated and 32% of the drag is reduced. When the maximum tangential motion reaches 2.5 times of the free-stream velocity, thrust is generated and the power savings ratio, defined as the ratio of the reduced drag power to the control input power, reaches 19.6. The mechanism of drag reduction is attributed to the change of the radial gradient of spanwise vorticity (partial r \\hat{ζ } ) and the subsequent accelerated pressure recovery from the uncontrolled separation points to the rear stagnation point.
Zhao, Ling; Zhu, Nan-Wen; Wang, Xiao-Hui
2008-01-01
Bioleaching of spent Ni-Cd batteries using acidified sewage sludge was carried out in a continuous flow two-step leaching system including an acidifying reactor and a leaching reactor. Two systems operated about 30d to achieve almost complete dissolution of heavy metals Ni, Cd and Co in four Ni-Cd batteries. Ferrous sulphate and elemental sulfur were used as two different substrates to culture indigenous thiobacilli in sewage sludge. pH and ORP of the acidifying reactor was stabilized around 2.3 and 334mV for the iron-oxidizing system and 1.2 and 390mV for the sulfur-oxidizing system. It was opposite to the acidifying reactor, the pH/ORP in the leaching reactor of the iron-oxidizing system was relatively lower/higher than that of the sulphur-oxidizing system in the first 17d. The metal dissolution, in the first 12-16d, was faster in the iron-oxidizing system than in the sulphur-oxidizing system due to the lower pH. In the iron-oxidizing system, the maximum solubilization of cadmium (2500mg l(-1)) and cobalt (260mg l(-1)) can be reached at day 6-8 and the most of metal nickel was leached in the first 16d. But in the sulphur-oxidizing system there was a lag period of 4-8d to reach the maximum solubilization of cadmium and cobalt. The maximum dissolution of nickel hydroxide (1400mg l(-1)) and metallic nickel (2300mg l(-1)) occurred at about day 12 and day 20, respectively.
RXTE spectra of the Galactic microquasar GRO J1655-40 during the 2005 outburst
NASA Astrophysics Data System (ADS)
Saito, Koji; Yamaoka, K.; Fukuyama, M.; Miyakawa, T. G.; Yoshida, A.; Homan, J.
We report on the results of a detailed spectral analysis of 389 RXTE observations of the Galac- tic microquasar GRO J1655-40, performed during its 2005 outburst. The maximum luminosity reached during this outburst was 1.4 times higher than in the previous (1996-1997) outburst. However, the spectral behavior during the two outbursts was very similar. In particular, L disk was 4 proportional to Tin up to the same critical luminosity and in both outbursts there were periods during which the energy spectra were very soft, but could not be fit with standard disk models.
Experimental study on the effect of calcination on the volcanic ash activity of diatomite
NASA Astrophysics Data System (ADS)
Xiao, Liguang; Pang, Bo
2017-09-01
The volcanic ash activity of diatomite was studied under the conditions of aerobic calcination and vacuum calcination by the combined water rate method, it was characterized by XRD, BET and SEM. The results showed that the volcanic ash activity of diatomite under vacuum conditions was higher than that of aerobic calcination, 600°C vacuum calcination 2h, the combined water rate of diatomite-Ca(OH)2-H2O system was increased from 6.24% to 71.43%, the volcanic ash activity reached the maximum value, the specific surface
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ivanov, I. A., E-mail: I.A.Ivanov@inp.nsk.su; Burdakov, A. V.; Burmasov, V. S.
2017-02-15
Results of spectral and magnetic diagnostics of plasma differential rotation in the GOL-3 multiplemirror trap are presented. It is shown that the maximum frequency of plasma rotation about the longitudinal axis reaches 0.5 MHz during the injection of a relativistic electron beam into the plasma. The data of two diagnostics agree if there is a region with a higher rotation frequency near the boundary of the electron beam. Plasma differential rotation can be an additional factor stabilizing interchange modes in the GOL-3 facility.
Disintegration impact on sludge digestion process.
Dauknys, Regimantas; Rimeika, Mindaugas; Jankeliūnaitė, Eglė; Mažeikienė, Aušra
2016-11-01
The anaerobic sludge digestion is a widely used method for sludge stabilization in wastewater treatment plant. This process can be improved by applying the sludge disintegration methods. As the sludge disintegration is not investigated enough, an analysis of how the application of thermal hydrolysis affects the sludge digestion process based on full-scale data was conducted. The results showed that the maximum volatile suspended solids (VSS) destruction reached the value of 65% independently on the application of thermal hydrolysis. The average VSS destruction increased by 14% when thermal hydrolysis was applied. In order to have the maximum VSS reduction and biogas production, it is recommended to keep the maximum defined VSS loading of 5.7 kg VSS/m(3)/d when the thermal hydrolysis is applied and to keep the VSS loading between 2.1-2.4 kg VSS/m(3)/d when the disintegration of sludge is not applied. The application of thermal hydrolysis leads to an approximately 2.5 times higher VSS loading maintenance comparing VSS loading without the disintegration; therefore, digesters with 1.8 times smaller volume is required.
Failure mechanics in low-velocity impacts on thin composite plates
NASA Technical Reports Server (NTRS)
Elber, W.
1983-01-01
Eight-ply quasi-isotropic composite plates of Thornel 300 graphite in Narmco 5208 epoxy resin (T300/5208) were tested to establish the degree of equivalence between low-velocity impact and static testing. Both the deformation and failure mechanics under impact were representable by static indentation tests. Under low-velocity impacts such as tool drops, the dominant deformation mode of the plates was the first, or static, mode. Higher modes are excited on contact, but they decay significantly by the time the first-mode load reaches a maximum. The delamination patterns were observed by X-ray analysis. The areas of maximum delamination patterns were observed by X-ray analysis. The areas of maximum delamination coincided with the areas of highest peel stresses. The extent of delamination was similar for static and impact tests. Fiber failure damage was established by tensile tests on small fiber bundles obtained by deplying test specimens. The onset of fiber damage was in internal plies near the lower surface of the plates. The distribution and amount of fiber damage was similar fo impact and static tests.
Assessment of Heat Hazard during the Polymerization of Selected Light-Sensitive Dental Materials.
Janeczek, Maciej; Herman, Katarzyna; Fita, Katarzyna; Dudek, Krzysztof; Kowalczyk-Zając, Małgorzata; Czajczyńska-Waszkiewicz, Agnieszka; Piesiak-Pańczyszyn, Dagmara; Kosior, Piotr; Dobrzyński, Maciej
2016-01-01
Introduction. Polymerization of light-cured dental materials used for restoration of hard tooth tissue may lead to an increase in temperature that may have negative consequence for pulp vitality. Aim. The aim of this study was to determine maximum temperatures reached during the polymerization of selected dental materials, as well as the time that is needed for samples of sizes similar to those used in clinical practice to reach these temperatures. Materials and Methods. The study involved four composite restorative materials, one lining material and a dentine bonding agent. The polymerization was conducted with the use of a diode light-curing unit. The measurements of the external surface temperature of the samples were carried out using the Thermovision®550 thermal camera. Results. The examined materials significantly differed in terms of the maximum temperatures values they reached, as well as the time required for reaching the temperatures. A statistically significant positive correlation of the maximum temperature and the sample weight was observed. Conclusions. In clinical practice, it is crucial to bear in mind the risk of thermal damage involved in the application of light-cured materials. It can be reduced by using thin increments of composite materials.
NASA Astrophysics Data System (ADS)
Fu, Yubin; Lu, Zhikai; Zai, Xuerong; Wang, Jian
2015-08-01
Electrode materials have an important effect on the property of microbial fuel cell (MFC). Carbon foam is utilized as an anode and further modified by urea to improve its performance in marine benthic microbial fuel cell (BMFC) with higher voltage and output power. The electrochemical properties of plain carbon foam (PC) and urea-modified carbon foam (UC) are measured respectively. Results show that the UC obtains better wettability after its modification and higher anti-polarization ability than the PC. A novel phenomenon has been found that the electrical potential of the modified UC anode is nearly 100 mV lower than that of the PC, reaching -570 ±10 mV ( vs. SCE), and that it also has a much higher electron transfer kinetic activity, reaching 9399.4 mW m-2, which is 566.2-fold higher than that from plain graphite anode (PG). The fuel cell containing the UC anode has the maximum power density (256.0 mW m-2) among the three different BMFCs. Urea would enhance the bacteria biofilm formation with a more diverse microbial community and maintain more electrons, leading to a lower anodic redox potential and higher power output. The paper primarily analyzes why the electrical potential of the modified anode becomes much lower than that of others after urea modification. These results can be utilized to construct a novel BMFC with higher output power and to design the conditioner of voltage booster with a higher conversion ratio. Finally, the carbon foam with a bigger pore size would be a potential anodic material in conventional MFC.
Melquiades, Fábio L; Thomaz, Edivaldo L
2016-05-01
An important aspect for the evaluation of fire effects in slash-and-burn agricultural system, as well as in wildfire, is the soil burn severity. The objective of this study is to estimate the maximum temperature reached in real soil burn events using energy dispersive X-ray fluorescence (EDXRF) as an analytical tool, combined with partial least square (PLS) regression. Muffle-heated soil samples were used for PLS regression model calibration and two real slash-and-burn soils were tested as external samples in the model. It was possible to associate EDXRF spectra alterations to the maximum temperature reached in the heat affected soils with about 17% relative standard deviation. The results are promising since the analysis is fast, nondestructive, and conducted after the burn event, although local calibration for each type of burned soil is necessary. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.
Comparison of three systems of solar water heating by thermosiphon
NASA Astrophysics Data System (ADS)
Hernández, E.; Guzmán, R. E.
2016-02-01
The main purpose of this project was to elaborate a comparison between three water heating systems; using two plane water heating solar collector and another using a vacuum tube heater, all of them are on top of the cafeteria's roof on building of the “Universidad Pontificia Bolivariana” in Bucaramanga, Colombia. Through testing was determined each type of water heating systems' performance, where the Stainless Steel tube collector reached a maximum efficiency of 71.58%, the Copper Tubing Collector a maximum value of 76.31% and for the Vacuum Tube Heater Collector a maximum efficiency of 72.33%. The collector with copper coil was the system more efficient. So, taking into account the Performance and Temperature Curves, along with the weather conditions at the time of the testing we determined that the most efficient Solar Heating System is the one using a Vacuum Tube Heater Collector. Reaching a maximum efficiency of 72.33% and a maximum temperature of 62.6°C.
Transmission of electric fields due to distributed cloud charges in the atmosphere-ionosphere system
NASA Astrophysics Data System (ADS)
Paul, Suman; De, S. S.; Haldar, D. K.; Guha, G.
2017-10-01
The transmission of electric fields in the lower atmosphere by thunder clouds with a suitable charge distribution profile has been modeled. The electromagnetic responses of the atmosphere are presented through Maxwell's equations together with a time-varying source charge distribution. The conductivities are taken to be exponentially graded function of altitude. The radial and vertical electric field components are derived for isotropic, anisotropic and thundercloud regions. The analytical solutions for the total Maxwell's current which flows from the cloud into the ionosphere under DC and quasi-static conditions are obtained for isotropic region. We found that the effect of charge distribution in thunderclouds produced by lightning discharges diminishes rapidly with increasing altitudes. Also, it is found that time to reach Maxwell's currents a maximum is higher for higher altitudes.
Development of a Diet Quality Index Adapted for Pregnant Women
Crivellenti, Lívia Castro; Zuccolotto, Daniela Cristina Candelas; Sartorelli, Daniela Saes
2018-01-01
ABSTRACT OBJECTIVE: To develop a Diet Quality Index Adapted for Pregnant Women (IQDAG) and to evaluate its relation with the characteristics of women treated at the Brazilian Unified Health System. METHODS: The data on food intake come from a cross-sectional study carried out with 785 adult pregnant women in the city of Ribeirão Preto, state of São Paulo, Brazil, between 2011 and 2012. The index was based on the recommendations of the Brazilian Ministry of Health, previous national dietary indexes, and the new Dietary Guidelines for the Brazilian Population. We used the ANOVA, Kruskal-Wallis, and chi-square tests to describe the quality of the diet according to the characteristics of the mother. RESULTS: The IQDAG has nine components, and it is represented by three food groups (in servings/1,000 kcal), five nutrients, and a moderator component. A high proportion of pregnant women reached the maximum score for the components of legumes and vegetables. However, few women reached the maximum score for consumption of fresh fruits, fiber, omega-3, calcium, folate, iron, and ultra-processed foods. We verified a better quality of diet among older and eutrophic pregnant women who reported practicing more physical activity and taking dietary supplements. We also observed the highest index score among women with higher intake of carbohydrates, proteins, vitamins C, E, and A, and minerals calcium, folate, and iron, as well as among those with lower intake of total fats and saturated fats. CONCLUSIONS: This dietary index is unprecedented in incorporating the recommendation of the new Dietary Guidelines for the Brazilian Population regarding the moderation of the consumption of ultra-processed foods. It was useful in evaluating the quality of the diet of pregnant women and we verified a higher score among older and eutrophic women who reported a healthy lifestyle. Strategies are needed to promote a higher consumption of fresh fruits, foods high in fiber, omega-3, calcium, folate, iron, and minimally processed foods in pregnant women. PMID:29791675
Suinyuy, Terence N; Donaldson, John S; Johnson, Steven D
2013-09-01
Ontogenetic patterns of odour emissions and heating associated with plant reproductive structures may have profound effects on insect behaviour, and consequently on pollination. In some cycads, notably Macrozamia, temporal changes in emission of specific odour compounds and temperature have been interpreted as a 'push-pull' interaction in which pollinators are either attracted or repelled according to the concentration of the emitted volatiles. To establish which mechanisms occur in the large Encephalartos cycad clade, the temporal patterns of volatile emissions, heating and pollinator activity of cones of Encephalartos villosus in the Eastern Cape (EC) and KwaZulu Natal (KZN) of South Africa were investigated. Gas chromatography-mass spectrometry (GC-MS) analyses of Encephalartos villosus cone volatiles showed that emissions, dominated by eucalyptol and 2-isopropyl-3-methoxypyrazine in EC populations and (3E)-1,3-octadiene and (3E,5Z)-1,3,5-octatriene in the KZN populations, varied across developmental stages but did not vary significantly on a daily cycle. Heating in male cones was higher at dehiscence than during pre- and post-dehiscence, and reached a maximum at about 1830 h when temperatures were between 7·0 and 12·0 °C above ambient. Daily heating of female cones was less pronounced and reached a maximum at about 1345 h when it was on average between 0·9 and 3·0 °C above ambient. Insect abundance on male cones was higher at dehiscence than at the other stages and significantly higher in the afternoon than in the morning and evening. There are pronounced developmental changes in volatile emissions and heating in E. villosus cones, as well as strong daily changes in thermogenesis. Daily patterns of volatile emissions and pollinator abundance in E. villosus are different from those observed in some Macrozamia cycads and not consistent with the push-pull pattern as periods of peak odour emission do not coincide with mass exodus of insects from male cones.
Viewer-centered and body-centered frames of reference in direct visuomotor transformations.
Carrozzo, M; McIntyre, J; Zago, M; Lacquaniti, F
1999-11-01
It has been hypothesized that the end-point position of reaching may be specified in an egocentric frame of reference. In most previous studies, however, reaching was toward a memorized target, rather than an actual target. Thus, the role played by sensorimotor transformation could not be disassociated from the role played by storage in short-term memory. In the present study the direct process of sensorimotor transformation was investigated in reaching toward continuously visible targets that need not be stored in memory. A virtual reality system was used to present visual targets in different three-dimensional (3D) locations in two different tasks, one with visual feedback of the hand and arm position (Seen Hand) and the other without such feedback (Unseen Hand). In the Seen Hand task, the axes of maximum variability and of maximum contraction converge toward the mid-point between the eyes. In the Unseen Hand task only the maximum contraction correlates with the sight-line and the axes of maximum variability are not viewer-centered but rotate anti-clockwise around the body and the effector arm during the move from the right to the left workspace. The bulk of findings from these and previous experiments support the hypothesis of a two-stage process, with a gradual transformation from viewer-centered to body-centered and arm-centered coordinates. Retinal, extra-retinal and arm-related signals appear to be progressively combined in superior and inferior parietal areas, giving rise to egocentric representations of the end-point position of reaching.
Handeland, S.O.; Wilkinson, E.; Sveinsbo, B.; McCormick, S.D.; Stefansson, S.O.
2004-01-01
Development of hypo-osmoregulatory ability, gill Na+,K +-ATPase activity, condition factor and growth in Atlantic salmon during parr-smolt transformation was studied in a 2??3 factorial design with three temperatures (12.0, 8.9??C and ambient, 2.4-11.9??C, mean: 6.0??C) and two farmed strains of smolts (Mowi and AquaGen). The development of hypo-osmoregulatory ability and gill Na+,K+-ATPase activity were significantly influenced by freshwater temperature. In smolts raised at 12.0??C, maximum gill Na+,K+-ATPase activity was reached in late April, compared with late May and mid-June in the 8.9??C and ambient groups, respectively. In all groups, peak gill Na+,K +-ATPase activity was seen 350 degree days (d??C) after the onset of the smolt-related increase in enzyme activity (30 March) The period of high enzyme activity (>90% of maximum) lasted approximately 250 d??C. No distinct peak level in gill Na+,K+-ATPase activity was seen in the AquaGen strain at ambient temperature. Elevated temperatures also accelerated the loss of hypo-osmoregulatory capacity. In all groups, gill Na+,K+-ATPase activity reached pre-smolt levels approximately 500 d??C after the calculated peak level. Growth rate in freshwater was influenced by strain, temperature and their interaction, with the Mowi strain showing a higher growth rate than the AquaGen strain at 8.9??C and ambient temperatures. Following transfer to seawater, a higher growth rate was recorded in smolts from the Mowi strain than the AquaGen strain from the ambient temperature regime. Temperature influences the development and loss of smolt characteristics in both strains, and has long-term effects on post-smolt performance in seawater. ?? 2004 Elsevier B.V. All rights reserved.
Methylmercury in flood-control impoundments and natural waters of northwestern Minnesota, 1997-99
Brigham, M.E.; Krabbenhoft, D.P.; Olson, M.L.; DeWild, J.F.
2002-01-01
We studied methylmercury (MeHg) and total mercury (HgT) in impounded and natural surface waters in northwestern Minnesota, in settings ranging from agricultural to undeveloped. In a recently constructed (1995) permanent-pool impoundment, MeHg levels typically increased from inflow to outflow during 1997; this trend broke down from late 1998 to early 1999. MeHg levels in the outflow reached seasonal maxima in mid-summer (maximum of 1.0 ng L−1 in July 1997) and late-winter (maximum of 6.6 ng L−1 in February 1999), and are comparable to high levels observed in new hydroelectric reservoirs in Canada. Spring and autumn MeHg levels were typically about 0.1–0.2 ng L−1. Overall, MeHg levels in both the inflow (a ditch that drains peatlands) and outflow were significantly higher than in three nearby reference natural lakes. Eleven older permanent-pool impoundments and six natural lakes in northwestern Minnesota were sampled five times. The impoundments typically had higher MeHg levels (0.071–8.36 ng L−1) than natural lakes. Five of six lakes MeHg levels typical of uncontaminated lakes (0.014–1.04 ng L−1) with highest levels in late winter, whereas a hypereutrophic lake had high levels (0.37–3.67 ng L−1) with highest levels in mid-summer. Seven temporary-pool impoundments were sampled during summer high-flow events. Temporary-pool impoundments that retained water for about 10–15 days after innundation yielded pronounced increases in MeHg from inflow to outflow, in one case reaching 4.6 ng L−1, which was about 2 ng L−1 greater than the mean inflow concentration during the runoff event.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Meyer, T. L.; Woodward, P. M., E-mail: woodward.55@osu.edu; Dixit, M.
2014-07-07
Sr₂FeMoO₆ (SFMO) films were grown on SrTiO₃ (100)- and (111)-oriented substrates via pulsed laser deposition (PLD). In order to study the fundamental characteristics of deposition, films were grown in two different PLD chambers. In chamber I, the best films were grown with a relatively long substrate-to-target distance (89 mm), high substrate temperature (850 °C), and low pressure (50 mTorr) in a 95% Ar/5% H₂ atmosphere. Although X-ray diffraction (XRD) measurements indicate these films are single phase, Rutherford Backscattering (RBS) measurements reveal considerable non-stoichiometry, corresponding to a Sr₂Fe{sub 1–x}Mo{sub 1+x}O₆ composition with x≅0.2–0.3. This level of non-stoichiometry results in inferior magneticmore » properties. In chamber II, the best films were grown with a much shorter substrate-to-target distance (38 mm), lower temperature (680 °C), and higher pressure (225 mTorr). XRD measurements show that the films are single phase, and RBS measurements indicate that they are nearly stoichiometric. The degree of ordering between Fe and Mo was dependent on both the temperature and pressure used during deposition, reaching a maximum order parameter of 85%. The saturation magnetization increases as the Fe/Mo ordering increases, reaching a maximum of 2.4 μ B/f.u. Based on prior studies of bulk samples, one would expect a higher saturation magnetization for this degree of Fe/Mo order. The presence of extra strontium oxide layers in the form of Ruddlesden-Popper intergrowths appears to be responsible for the lower than expected saturation magnetization of these films.« less
Strube-Bloss, Martin F.; Herrera-Valdez, Marco A.; Smith, Brian H.
2012-01-01
Neural representations of odors are subject to computations that involve sequentially convergent and divergent anatomical connections across different areas of the brains in both mammals and insects. Furthermore, in both mammals and insects higher order brain areas are connected via feedback connections. In order to understand the transformations and interactions that this connectivity make possible, an ideal experiment would compare neural responses across different, sequential processing levels. Here we present results of recordings from a first order olfactory neuropile – the antennal lobe (AL) – and a higher order multimodal integration and learning center – the mushroom body (MB) – in the honey bee brain. We recorded projection neurons (PN) of the AL and extrinsic neurons (EN) of the MB, which provide the outputs from the two neuropils. Recordings at each level were made in different animals in some experiments and simultaneously in the same animal in others. We presented two odors and their mixture to compare odor response dynamics as well as classification speed and accuracy at each neural processing level. Surprisingly, the EN ensemble significantly starts separating odor stimuli rapidly and before the PN ensemble has reached significant separation. Furthermore the EN ensemble at the MB output reaches a maximum separation of odors between 84–120 ms after odor onset, which is 26 to 133 ms faster than the maximum separation at the AL output ensemble two synapses earlier in processing. It is likely that a subset of very fast PNs, which respond before the ENs, may initiate the rapid EN ensemble response. We suggest therefore that the timing of the EN ensemble activity would allow retroactive integration of its signal into the ongoing computation of the AL via centrifugal feedback. PMID:23209711
Chai, Zhao Yang; He, Zhi Li; Deng, Yun Yan; Yang, Yu Feng; Tang, Ying Zhong
2018-02-01
Plankton diversity reflects the quality and health of waters and should be monitored as a critical feature of marine ecosystems. This study applied a pair of 28S rRNA gene-specific primers and pyrosequencing to assess the effects of large-scale cultivation of the seaweed Gracilaria lemaneiformis on the biodiversity of eukaryotic plankton community in the coastal water of Guangdong, China. With 1 million sequences (2,221 operational taxonomic units [OTUs]) obtained from 51 samples, we found that the biodiversity of eukaryotic plankton community was significantly higher in the seaweed cultivation area than that in the nearby control area as reflected in OTU richness, evenness (Shannon-Wiener index) and dominance (Simpson index) for total plankton community and its four subcategories when Gracilaria biomass reached the maximum, while no such a significant difference was observed before seaweed inoculation. Our laboratory experiment using an artificial phytoplankton community of nine species observed the same effects of Gracilaria exposure. Principal component analysis and principal coordinates analysis showed the plankton community structure in cultivation area markedly differed from the control area when Gracilaria biomass reached its maximum. Redundancy analysis showed that G. lemaneiformis was the critical factor in controlling the dynamics of eukaryotic plankton communities in the studied coastal ecosystem. Our results explicitly demonstrated G. lemaneiformis cultivation could enhance biodiversity of plankton community via allelopathy, which prevents one or several plankton species from blooming and consequently maintains a relatively higher biodiversity. Our study provided further support for using large-scale G. lemaneiformis cultivation as an effective approach for improving costal ecosystem health. © 2018 John Wiley & Sons Ltd.
Oren, Ram; Pataki, Diane E
2001-05-01
Responses of forests to changes in environmental conditions reflect the integrated behavior of their constituent species. We investigated sap flux-scaled transpiration responses of two species prevalent in upland eastern hardwood forests, Quercus alba in the upper canopy and Acer rubrum in the low to mid canopy, to changes in photosynthetically active radiation above the canopy (Q o ), vapor pressure deficit within the canopy (D), and soil moisture depletion during an entire growing season. Water loss before bud break (presumably through the bark) increased linearly with D, reaching 8% of daily stand transpiration (E C ) as measured when leaf area index was at maximum, and accounting for 5% of annual water loss. After leaves were completely expanded and when soil moisture was high, sap flux-scaled daily E C increased linearly with the daily sum of Q o . Species differences in this response were observed. Q. alba reached a maximum transpiration at low Q o , while A. rubrum showed increasing transpiration with Q o at all light levels. Daily E C increased in response to daily average D, with an asymptotic response due to the behavior of Q. alba. Transpiration of A. rubrum showed a greater response to soil moisture depletion than did that of Q. alba. When evaluated at a half-hourly scale under high Q o , mean canopy stomatal conductance (G S ) of individuals decreased with D. The sensitivity of G S to D was greater in species with higher intrinsic G S . Regardless of position in the canopy, diffuse-porous species in this and an additional, more mesic stand showed higher G S and greater stomatal sensitivity to environmental variation than do ring-porous species.
The Major Qualitative Characteristics of Olive (Olea europaea L.) Cultivated in Southwest China.
Cheng, Zizhang; Zhan, Mingming; Yang, Zeshen; Zumstein, Kristina; Chen, Huaping; Huang, Qianming
2017-01-01
Olive trees, originated from Mediterranean, have been cultivated in China for decades and show great adaption to local environment. However, research on this topic is limited. In this study, the major qualitative characteristics and changes of olive grown in southwest China were investigated. The results showed that oil accumulated during fruit development and reached its maximum value when fruit had fully ripened. Phenolic and flavonoid contents increase rapidly in the early growth stage (0-90 DAFB) and then begin to decrease as fruit ripens. Compared with olive from the Mediterranean, olive from China has special characteristics: higher moisture content in the fruit combined with lower percentages of unsaturated fatty acids and oil content. This is due to southwest China's climate which is wetter and cooler compared to the Mediterranean. Our study suggests that southwest China's higher annual rainfall might contribute to higher fruit moisture content while its low temperatures would be conducive to higher unsaturated fatty acid levels in the fruit.
The Major Qualitative Characteristics of Olive (Olea europaea L.) Cultivated in Southwest China
Cheng, Zizhang; Zhan, Mingming; Yang, Zeshen; Zumstein, Kristina; Chen, Huaping; Huang, Qianming
2017-01-01
Olive trees, originated from Mediterranean, have been cultivated in China for decades and show great adaption to local environment. However, research on this topic is limited. In this study, the major qualitative characteristics and changes of olive grown in southwest China were investigated. The results showed that oil accumulated during fruit development and reached its maximum value when fruit had fully ripened. Phenolic and flavonoid contents increase rapidly in the early growth stage (0–90 DAFB) and then begin to decrease as fruit ripens. Compared with olive from the Mediterranean, olive from China has special characteristics: higher moisture content in the fruit combined with lower percentages of unsaturated fatty acids and oil content. This is due to southwest China's climate which is wetter and cooler compared to the Mediterranean. Our study suggests that southwest China's higher annual rainfall might contribute to higher fruit moisture content while its low temperatures would be conducive to higher unsaturated fatty acid levels in the fruit. PMID:28579990
Fan, Xiaoguang; Cheng, Gang; Zhang, Hongjia; Li, Menghua; Wang, Shizeng; Yuan, Qipeng
2014-12-19
Corncob residue is a cellulose-rich byproduct obtained from industrial xylose production via dilute acid hydrolysis processes. Enzymatic hydrolysis of cellulose in acid hydrolysis residue of corncob (AHRC) is often less efficient without further pretreatment. In this work, the process characteristics of acid impregnated steam explosion were studied in conjunction with a dilute acid process, and their effects on physiochemical changes and enzymatic saccharification of corncob residue were compared. With the acid impregnated steam explosion process, both higher xylose recovery and higher cellulose conversion were obtained. The maximum conversion of cellulose in acid impregnated steam explosion residue of corncob (ASERC) reached 85.3%, which was 1.6 times higher than that of AHRC. Biomass compositional analysis showed similar cellulose and lignin content in ASERC and AHRC. XRD analysis demonstrated comparable crystallinity of ASERC and AHRC. The improved enzymatic hydrolysis efficiency was attributed to higher porosity in ASERC, measured by mercury porosimetry. Copyright © 2014 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Gonor, Alexander; Hooton, Irene
2006-07-01
Impact of a rigid projectile (impactor), against a metal target and a condensed explosive surface considered as the important process accompanying the normal entry of a rigid projectile into a target, was overlooked in the preceding studies. Within the framework of accurate shock wave theory, the flow-field, behind the shock wave attached to the perimeter of the adjoined surface, was defined. An important result is the peak pressure rises at points along the target surface away from the stagnation point. The maximum values of the peak pressure are 2.2 to 3.2 times higher for the metallic and soft targets (nitromethane, PBX 9502), than peak pressure values at the stagnation point. This effect changes the commonly held notion that the maximum peak pressure is reached at the projectile stagnation point. In the present study the interaction of a spherical decaying blast wave, caused by an underwater explosion, with a piece-wise plane target, having corner configurations, is investigated. The numerical calculation results in the determination of the vulnerable spots on the target, where the maximum peak overpressure surpassed that for the head-on shock wave reflection by a factor of 4.
[In vitro evaluation of cutaneous allergic reaction induced by chemicals using dendritic cells].
Zhang, Yu-bin; Lin, Hui-fen; Lv, Luo; Hua, Wei-guang; Tian, Fang; Shen, Guang-zu; Xia, Zhao-lin; Jin, Xi-peng
2008-03-01
To investigate the use of dendritic cells derived from mice bone marrow to evaluate the cutaneous allergic reaction induced by chemical sensitizers. Dendritic cells derived from mice bone marrow were cultured and administrated with 2, 4-dinitrochlorobenzene (DNCB), nickel sulfate (NiSO4), sodium dodecyl sulfate (SDS) and hexyl cinnamic aldehyde (HCA), respectively. Cell membrane molecule CD86 and extracellular IL-1 beta, IL-6 and IL-12 were detected after 0, 1, 6, 12, 24, 36, 48 hour's administration, respectively. CD86 expression reached the highest level after exposure to DNCB for 48 h, and increased by about 279% compared with the control (P < 0.05), while it was lower than that of control after administrated with NiSO4 and HCA for 1 h and 6 h, and SDS for 36 h, respectively (P < 0.05). Extracellular IL-1 beta increased greatly after exposure to NiSO4 just for 1 h, with the maximum at 48 h (298 pg/ml, P < 0.05), and after exposure to HCA for 6 h, with maximum at 48 h (84 pg/ml, P < 0.05). However, it didn't fluctuate significantly after administrated with DNCB and SDS respectively, compared with the control. Extracellular IL-6 increased significantly after exposure to NiSO4 for 1 h, with the maximum at 24 h (2152 pg/ml, P < 0.05). After exposure to HCA, extracellular IL-6 reached the maximum at 1 h (1403 pg/ml), and then it was decreased quickly, but still higher than the control (P < 0.05), while it didn't change significantly after treatment with DNCB and SDS, compared with the control (P > 0.05). Extracellular IL-12 was not detected out among all the groups. Chemical sensitizer DNCB could induce the high expression of CD86 on DC membrane, and NiSO4 and HCA could induce DC to release IL-1 beta and IL-6. However, the irritant SDS had no such effect.
Cytidine 5'-diphosphate reductase activity in phytohemagglutinin stimulated human lymphocytes.
Tyrsted, G; Gamulin, V
1979-01-01
The optimal conditions and the effect of deoxyribonucleoside triphosphates were determined for CDP reductase activity in PHA-stimulated lymphocytes. The enzymatic reaction showed an absolute requirement for ATP. In the absence of ATP, only dATP showed a minor stimulation of the reduction of CDP to dCDP. During transformation the CDP reductase activity reached a maximum at the same time as the four deoxyribonucleoside triphosphate pools, corresponding to mid S-phase at about 50 h after PHA addition. The DNA polymerase activity reached a maximum at 57 h. PMID:424294
Luo, Shun-Tao; Tian, Wen-Hong; Wang, Gang; Dong, Xiao-Yan; Yang, Li; Wu, Xiao-Bing
2009-11-01
GLuc (Gaussia luciferase) is a secreted luciferase with high sensitivity. In this study, we primarily compared expression character of PTTR with that of PCMV, relied on easy secretion, high sensitivity and simple and fast detection of GLuc. We firstly constructed two plasmids pAAV2-neo-TTR-GLuc and pAAV2-neo-CMV-GLuc. Then, 4 cell lines were transfected with the two plasmids in aid of Lipofectamine 2000, including Huh7 and HepG2, which are derived from liver cells, as well as HEK293 and HeLaS3 cells, which are non-liver cell lines. We monitored the expression of GLuc in the supernatant of these cell cultures at different time points post-transfection. Furthermore, we injected the two plasmids with different doses into BALB/c mice by the means of hydrodynamic delivery and monitored the GLuc expression in vivo with 2.5 microl tail tip blood since 2 h post-injection. The cell assay results suggested that the expression of GLuc driven by CMV promoter was significantly higher than that of GLuc driven by TTR promoter. And, the luciferase activity of GLuc driven by CMV promoter was 50-300 times higher than that of GLuc driven by TTR promoter in HEK293 and HeLaS3 cell lines, but less than 10 times higher than that of GLuc driven by TTR promoter in the HepG2 and Huh7 cell lines, indicating the relative liver-specificity of TTR promoter. In the animal assay, the higher luciferase activity was determined in CMV promoter group than in TTR promoter group at different doses of the two plasmids. But the expression patterns for the two promoters differed obviously. The expression of GLuc driven by CMV promoter reached the maximum 10 hours post-injection and declined rapidly; while the expression of GLuc driven by TTR promoter reached the maximum 48 hours after delivery, and declined very slowly. These results implied that PTTR could keep expression of driven gene in a long time although its expression intensity is lower than PCMV's. Thus, it is more suitable for maintaining longer expression of target genes in liver.
Comparative study of (0001) and (11\\bar{2}2) InGaN based light emitting diodes
NASA Astrophysics Data System (ADS)
Pristovsek, Markus; Humphreys, Colin J.; Bauer, Sebastian; Knab, Manuel; Thonke, Klaus; Kozlowski, Grzegorz; O'Mahony, Donagh; Maaskant, Pleun; Corbett, Brian
2016-05-01
We have systematically investigated the doping of (11\\bar{2}2) with Si and Mg by metal-organic vapour phase epitaxy for light emitting diodes (LEDs). By Si doping of GaN we reached electron concentrations close to 1020 cm-3, but the topography degrades above mid 1019 cm-3. By Mg doping we reached hole concentrations close to 5 × 1017 cm-3, using Mg partial pressures about 3× higher than those for (0001). Exceeding the maximum Mg partial pressure led to a quick degradation of the sample. Low resistivities as well as high hole concentrations required a growth temperature of 900 °C or higher. At optimised conditions the electrical properties as well as the photoluminescence of (11\\bar{2}2) p-GaN were similar to (0001) p-GaN. The best ohmic p-contacts were achieved by NiAg metallisation. A single quantum well LED emitting at 465 nm was realised on (0001) and (11\\bar{2}2). Droop (sub-linear increase of the light output power) occurred at much higher current densities on (11\\bar{2}2). However, the light output of the (0001) LED was higher than that of (11\\bar{2}2) until deep in the droop regime. Our LEDs as well as those in the literature indicate a reduction in efficiency from (0001) over semi-polar to non-polar orientations. We propose that reduced fields open a loss channel for carriers.
Barrio-Parra, F; Elío, J; De Miguel, E; García-González, J E; Izquierdo, M; Álvarez, R
2018-04-01
A total of 74 samples of soil, sediment, industrial sludge, and surface water were collected in a Mediterranean estuarine system in order to assess the potential ecological impact of elevated concentrations of Co and Mn associated with a Terephthalic (PTA) and Isophthalic (PIPA) acids production plant. Samples were analyzed for elemental composition (37 elements), pH, redox potential, organic carbon, and CaCO 3 content, and a group of 16 selected samples were additionally subjected to a Tessier sequential extraction. Co and Mn soil concentrations were significantly higher inside the industrial facility and around its perimeter than in background samples, and maximum dissolved Co and Mn concentrations were found in a creek near the plant's discharge point, reaching values 17,700 and 156 times higher than their respective background concentrations. The ecological risk was evaluated as a function of Co and Mn fractionation and bioavailability which were controlled by the environmental conditions generated by the advance of seawater into the estuarine system during high tide. Co appeared to precipitate near the river mouth due to the pH increase produced by the influence of seawater intrusion, reaching hazardous concentrations in sediments. In terms of their bioavailability and the corresponding risk assessment code, both Co and Mn present sediment concentrations that result in medium to high ecological risk whereas water concentrations of both elements reach values that more than double their corresponding Secondary Acute Values.
NASA Astrophysics Data System (ADS)
Lopes de Gerenyu, V. O.; Anichkin, A. E.; Avilov, V. K.; Kuznetsov, A. N.; Kurganova, I. N.
2015-02-01
Annual dynamics of CO2 fluxes from soils and the impact of the living activity of termites on them were studied in plain lagerstroemia semideciduous monsoon tropical forests of southern Vietnam. On the plot populated by Globitermes sulphureus and Odontotermes termites, a detailed study of the spatial heterogeneity of the CO2 emission from the surface of soil and termite mounds was performed in the wet and dry seasons. It was found that the average rate of the CO2 emission from termite mounds was two times and more higher than that from the background soil surface. In the dry season, it comprised 91 ± 7 mg C/m2 per h from the background soil and 196 ± 16 mg C/m2 per h from the termite mounds. In the wet season, the CO2 emission rate was considerably higher and reached 266 ± 40 and 520 ± 39 mg C/m2 per h, respectively. The maximum rates of CO2 fluxes were determined in the wet season in some of the measurement chambers installed on termite mounds; they reached 730-880 mg C/m2 per h. Though termite mounds occupy about 4% of the area of tropical forest ecosystems, the overall effect of termites on the carbon budget was more significant; according to our estimates, it reached up to 10% of the total efflux of CO2 from the soil surface.
Li, Shijia; Lord, Anton; Colic, Lejla; Krause, Anna Linda; Batra, Anil; Kretzschmar, Moritz A; Sweeney-Reed, Catherine M; Behnisch, Gusalija; Schott, Björn H; Walter, Martin
2017-01-01
Abstract Background The increasing use of ketamine as a potential rapid-onset antidepressant necessitates a better understanding of its effects on blood pressure and heart rate, well-known side effects at higher doses. For the subanesthetic dose used for depression, potential predictors of these cardiovascular effects are important factors influencing clinical decisions. Since ketamine influences the sympathetic nervous system, we investigated the impact of autonomic nervous system-related factors on the cardiovascular response: a genetic polymorphism in the norepinephrine transporter and gender effects. Methods Blood pressure and heart rate were monitored during and following administration of a subanesthetic dose of ketamine or placebo in 68 healthy participants (mean age 26.04 ±5.562 years) in a double-blind, randomized, controlled, parallel-design trial. The influences of baseline blood pressure/heart rate, gender, and of a polymorphism in the norepinephrine transporter gene (NET SLC6A2, rs28386840 [A-3081T]) on blood pressure and heart rate changes were investigated. To quantify changes in blood pressure and heart rate, we calculated the maximum change from baseline (ΔMAX) and the time until maximum change (TΔMAX). Results Systolic and diastolic blood pressure as well as heart rate increased significantly upon ketamine administration, but without reaching hypertensive levels. During administration, the systolic blood pressure at baseline (TP0Sys) correlated negatively with the time to achieve maximal systolic blood pressure (TΔMAXSys, P<.001). Furthermore, women showed higher maximal diastolic blood pressure change (ΔMAXDia, P<.001) and reached this peak earlier than men (TΔMAXDia, P=.017) at administration. NET rs28386840 [T] carriers reached their maximal systolic blood pressure during ketamine administration significantly earlier than [A] homozygous (TΔMAXSys, P=.030). In a combined regression model, both genetic polymorphism and TP0Sys were significant predictors of TΔMAXSys (P<.0005). Conclusions Subanesthetic ketamine increased both blood pressure and heart rate without causing hypertensive events. Furthermore, we identified gender and NET rs28386840 genotype as factors that predict increased cardiovascular sequelae of ketamine administration in our young, healthy study population providing a potential basis for establishing monitoring guidelines. PMID:29099972
PRESSMAN, ETAN; PEET, MARY M.; PHARR, D. MASON
2002-01-01
Continuous exposure of tomato ‘Trust’ to high temperatures (day/night temperatures of 32/26 °C) markedly reduced the number of pollen grains per flower and decreased viability. The effect of heat stress on pollen viability was associated with alterations in carbohydrate metabolism in various parts of the anther during its development. Under control, favourable temperature conditions (28/22 °C), starch accumulated in the pollen grains, where it reached a maximum value 3 d before anthesis; it then diminished towards anthesis. During anther development, the concentration of total soluble sugars gradually increased in the anther walls and in the pollen grains (but not in the locular fluid), reaching a maximum at anthesis. Continuous exposure of the plants to high temperatures (32/26 °C) prevented the transient increase in starch concentration and led to decreases in the concentrations of soluble sugars in the anther walls and the pollen grains. In the locular fluid, however, a higher soluble sugar concentration was detected under the high‐temperature regime throughout anther development. These results suggest that a major effect of heat stress on pollen development is a decrease in starch concentration 3 d before anthesis, which results in a decreased sugar concentration in the mature pollen grains. These events possibly contribute to the decreased pollen viability in tomato. PMID:12466104
Experimental Investigation of Axial and Beam-Riding Propulsive Physics with TEA CO{sub 2} laser
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kenoyer, D. A.; Salvador, I.; Myrabo, L. N.
2010-10-08
A twin Lumonics K922M pulsed TEA CO{sub 2} laser system (pulse duration of approximately 100 ns FWHM spike, with optional 1 {mu}s tail, depending upon laser gas mix) was employed to experimentally measure both axial thrust and beam-riding behavior of Type no. 200 lightcraft engines, using a ballistic pendulum and Angular Impulse Measurement Device (AIMD, respectively. Beam-riding forces and moments were examined along with engine thrust-vectoring behavior, as a function of: a) laser beam lateral offset from the vehicle axis of symmetry; b) laser pulse energy ({approx}12 to 40 joules); c) pulse duration (100 ns, and 1 {mu}s); and d)more » engine size (97.7 mm to 161.2 mm). Maximum lateral momentum coupling coefficients (C{sub M}) of 75 N-s/MJ were achieved with the K922M laser whereas previous PLVTS laser (420 J, 18 {mu}s duration) results reached only 15 N-s/MJ--an improvement of 5x. Maximum axial C{sub M} performance with the K922M reached 225 N-s/MJ, or about {approx}3x larger than the lateral C{sub M} values. These axial C{sub M} results are sharply higher than the 120 N/MW previously reported for long pulse (e.g., 10-18 {mu}s)CO{sub 2} electric discharge lasers.« less
Jin, Jiao; Lin, Feipeng; Liu, Ruohua; Xiao, Ting; Zheng, Jianlong; Qian, Guoping; Liu, Hongfu; Wen, Pihua
2017-12-05
Three kinds of mineral-supported polyethylene glycol (PEG) as form-stable composite phase change materials (CPCMs) were prepared to choose the most suitable CPCMs in asphalt pavements for the problems of asphalt pavements rutting diseases and urban heat islands. The microstructure and chemical structure of CPCMs were characterized by SEM, FT-IR and XRD. Thermal properties of the CPCMs were determined by TG and DSC. The maximum PEG absorption of diatomite (DI), expanded perlite (EP) and expanded vermiculite (EVM) could reach 72%, 67% and 73.6%, respectively. The melting temperatures and latent heat of CPCMs are in the range of 52-55 °C and 100-115 J/g, respectively. The results show that PEG/EP has the best thermal and chemical stability after 100 times of heating-cooling process. Moreover, crystallization fraction results show that PEG/EP has slightly higher latent heats than that of PEG/DI and PEG/EVM. Temperature-adjusting asphalt mixture was prepared by substituting the fine aggregates with PEG/EP CPCMs. The upper surface maximum temperature difference of temperature-adjusting asphalt mixture reaches about 7.0 °C in laboratory, and the surface peak temperature reduces up to 4.3 °C in the field experiment during a typical summer day, indicating a great potential application for regulating pavement temperature field and alleviating the urban heat islands.
NASA Astrophysics Data System (ADS)
Li, Zhen; Bai, Tongshuo; Dai, Letian; Wang, Fuwei; Tao, Jinjin; Meng, Shiting; Hu, Yunxiao; Wang, Shimei; Hu, Shuijin
2016-04-01
Phosphate solubilizing fungi (PSF) have huge potentials in enhancing release of phosphorus from fertilizer. Two PSF (NJDL-03 and NJDL-12) were isolated and identified as Penicillium oxalicum and Aspergillus niger respectively in this study. The quantification and identification of organic acids were performed by HPLC. Total concentrations of organic acids secreted by NJDL-03 and NJDL-12 are ~4000 and ~10,000 mg/L with pH values of 3.6 and 2.4 respectively after five-days culture. Oxalic acid dominates acidity in the medium due to its high concentration and high acidity constant. The two fungi were also cultured for five days with the initial pH values of the medium varied from 6.5 to 1.5. The biomass reached the maximum when the initial pH values are 4.5 for NJDL-03 and 2.5 for NJDL-12. The organic acids for NJDL-12 reach the maximum at the initial pH = 5.5. However, the acids by NJDL-03 continue to decrease and proliferation of the fungus terminates at pH = 2.5. The citric acid production increases significantly for NJDL-12 at acidic environment, whereas formic and oxalic acids decrease sharply for both two fungi. This study shows that NJDL-12 has higher ability in acid production and has stronger adaptability to acidic environment than NJDL-03.
Triglycerides and carotid intima-media thickness in ischemic stroke patients.
Batluk, Jana; Leonards, Christopher O; Grittner, Ulrike; Lange, Kristin Sophie; Schreiber, Stephan J; Endres, Matthias; Ebinger, Martin
2015-11-01
Common carotid artery intima-media thickness (CCA-IMT) is an established marker for atherosclerosis. The role of triglycerides in CCA-IMT remains controversial. We sought to determine if elevated fasting and post-challenge triglycerides are associated with CCA-IMT. All acute ischemic stroke patients who participated in the Berlin "Cream & Sugar" study in the Charité Virchow and Charité Mitte Campuses between January 2009 and January 2014 and underwent carotid artery ultrasound studies were eligible for inclusion. A combined oral glucose and triglyceride tolerance test was performed 3-7 days after first ever ischemic stroke. Patients were classified according to triglyceride metabolism-namely, (1) patients reaching a maximum triglyceride levels 3 h post-challenge ("fast metabolizers," n = 37), (2) patients with increasing triglycerides 4 (medium metabolizers, n = 64), and (3) 5 h post-challenge ("slow metabolizers," n = 44; 13 missing). We included 158 patients (34% female; mean age 63 years, SD 14). Absolute non-fasting triglyceride levels were positively associated with CCA-IMT. A final multiple regression model revealed that older age, more severe strokes, and higher levels of fasting triglycerides were significantly and independently associated with higher mean CCA-IMT. Older age, higher waist-to-hip ratio, and higher levels of thyroid-stimulating hormone were independently associated with higher maximum CCA-IMT. Fasting triglycerides but not post-challenge triglycerides associate with CCA-IMT. An oral fat challenge may not add information on atherosclerotic status in ischemic stroke patients. The Berlin "Cream & Sugar" study is registered with EudraCT (2009-010356-97) and clinicaltrials.gov (NCT 01378468). Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
Pérez-Castilla, Alejandro; Comfort, Paul; McMahon, John J; Pestaña-Melero, Francisco Luis; García-Ramos, Amador
2018-01-17
The aim of this study was to compare the temporal and mechanical variables between the concentric-only and eccentric-concentric bench press (BP) variants. Twenty-one men (age: 22.0±4.2 years, body mass: 73.4±7.7 kg, height: 177.2±8.0 cm; one-repetition maximum [1RM]: 1.12±0.12 kg⋅kg) were evaluated during the concentric-only and eccentric-concentric BP variants using 80% 1RM. Temporal (concentric phase duration, propulsive phase duration, and time to reach the maximum values of force, velocity, and power) and mechanical variables (force, velocity, and power), determined using a linear velocity transducer, were compared between both BP variants. All temporal variables were significantly lower during the eccentric-concentric BP compared to the concentric-only BP (P < 0.05; effect size [ES] range: 0.80-2.52). Maximum force as well as the mean values of velocity and power were significantly higher for the eccentric-concentric BP compared to the concentric-only BP (all P < 0.001; ES range: 2.87-3.58). However, trivial to small differences between both BP variants were observed for mean force (ES: 0.00-0.36) as well as for maximum velocity (ES: 0.40) and power (ES: 0.41). The stretch-shortening cycle (i.e., eccentric-concentric BP) mainly enhanced force production at the early portion of the concentric phase, but this potentiation effect gradually reduced over the latter part of the movement. Finally, force was higher for the concentric-only BP during 49% of the concentric phase duration. These results suggest that both BP variants should be included during resistance training programs in order to optimize force output at different points of the concentric phase.
Thermal buffering of concrete by seaweeds during a prolonged summer heatwave
NASA Astrophysics Data System (ADS)
Naylor, Larissa; Coombes, Martin
2014-05-01
Hard coastal infrastructure is subject to aggressive environmental conditions, including a suite of weathering processes in the intertidal zone. These processes, along with waves, lead to costly deterioration of coastal structures. Existing methods (e.g. coatings, less porous concrete) to reduce the risk of concrete deterioration rapidly lose their effectiveness in the intertidal zone. Additionally, a changing climate will lead to increased frequency of storms, higher sea level and higher extreme temperatures - and therefore, pose an increased risk of deterioration. Might there be a biogenic solution? New research (Coombes et al. 2013) has shown that fucoid seaweeds reduce microclimatic extremes and variability under normal summer conditions. The results presented here supplement these findings in two ways. First, they demonstrate that fucoid seaweeds act as a thermal buffer during a prolonged summer heatwave in Britain (July 2013). Over 36 days of continuous monitoring at two sites in Cornwall, UK, 19 of which were during the official heatwave, there were statistically significant differences (p = 0.000) in the maximum temperatures between thick seaweed (7.5 - 9.5 cm thickness) and thin seaweed (2 - 2.5 cm thickness) plots. Maximum temperatures reached 22°C and 33°C, for thick seaweed and thin seaweed plots, respectively. Variations in maximum temperatures between the two sites appear to be related to aspect. Second, the significantly different maximum temperature results between plots also demonstrate that seaweed thickness is an important factor influencing thermal buffering capacity. These data clearly demonstrate that fucoid seaweeds buffer concrete seawalls against extreme temperature fluxes during a heatwave, probably limiting the efficiency of deteriorative processes such as thermal expansion and contraction and salt crystallisation.
Naidenko, S V; Ivanov, E A; Lukarevskiĭ, V S; Hernandez-Blanko, J A; Sorokin, P A; Litvinov, M N; Kotliar, A K; Rozhnov, V V
2011-01-01
A noninvasive evaluation method of hypothalamo-pituitary-adrenals axis (HPA) activity in the Siberian tiger was verified. Comparison of the activity level of HPA in Siberian tigers in the wild and in captivity, and their alterations over the year was carried out. Significant seasonal deviations between activity levels of HPA in tigers in captivity were not found. In the wild, this level was significantly higher, reaching the maximum from November to January, which can be related with an unfavorable influence on tigers in low temperatures and deep snow cover.
High-redshift galaxy populations.
Hu, Esther M; Cowie, Lennox L
2006-04-27
We now see many galaxies as they were only 800 million years after the Big Bang, and that limit may soon be exceeded when wide-field infrared detectors are widely available. Multi-wavelength studies show that there was relatively little star formation at very early times and that star formation was at its maximum at about half the age of the Universe. A small number of high-redshift objects have been found by targeting X-ray and radio sources and most recently, gamma-ray bursts. The gamma-ray burst sources may provide a way to reach even higher-redshift galaxies in the future, and to probe the first generation of stars.
Half-Heusler (TiZrHf)NiSn Unileg Module with High Powder Density.
Populoh, Sascha; Brunko, Oliver C; Gałązka, Krzysztof; Xie, Wenjie; Weidenkaff, Anke
2013-03-27
(TiZrHf)NiSn half-Heusler compounds were prepared by arc melting and their thermoelectric properties characterized in the temperature range between 325 K and 857 K, resulting in a Figure of Merit ZT ≈ 0.45. Furthermore, the prepared samples were used to construct a unileg module. This module was characterized in a homemade thermoelectric module measurement stand and yielded 275 mW/cm² and a maximum volumetric power density of 700 mW/cm³. This was reached using normal silver paint as a contacting material; from an improved contacting, much higher power yields are to be expected.
Half-Heusler (TiZrHf)NiSn Unileg Module with High Powder Density
Populoh, Sascha; Brunko, Oliver C.; Gałązka, Krzysztof; Xie, Wenjie; Weidenkaff, Anke
2013-01-01
(TiZrHf)NiSn half-Heusler compounds were prepared by arc melting and their thermoelectric properties characterized in the temperature range between 325 K and 857 K, resulting in a Figure of Merit ZT ≈ 0.45. Furthermore, the prepared samples were used to construct a unileg module. This module was characterized in a homemade thermoelectric module measurement stand and yielded 275 mW/cm2 and a maximum volumetric power density of 700 mW/cm3. This was reached using normal silver paint as a contacting material; from an improved contacting, much higher power yields are to be expected. PMID:28809212
Yalcin, Seda Karasu; Yesim Ozbas, Z.
2008-01-01
The study was performed in a batch system in order to determine the effects of pH and temperature on growth and glycerol production kinetics of two indigenous wine yeast strains Saccharomyces cerevisiae Kalecik 1 and Narince 3. The highest values of dry mass and specific growth rate were obtained at pH 4.00 for both of the strains. Maximum specific glycerol production rates were obtained at pH 5.92 and 6.27 for the strains Kalecik 1 and Narince 3, respectively. Kalecik 1 strain produced maximum 8.8 gL−1 of glycerol at pH 6.46. Maximum glycerol concentration obtained by the strain Narince 3 was 9.1 gL−1 at pH 6.48. Both yeasts reached maximum specific growth rate at 30°C. Optimum temperature range for glycerol production was determined as 25-30°C for the strain Kalecik 1. The strain Narince 3 reached maximum specific glycerol production rate at 30°C. Maximum glycerol concentrations at 30°C were obtained as 8.5 and 7.6 gL−1 for Kalecik 1 and Narince 3, respectively. PMID:24031225
User embracement with risk classification in an emergency care unit: an evaluative study.
Hermida, Patrícia Madalena Vieira; Nascimento, Eliane Regina Pereira do; Echevarría-Guanilo, Maria Elena; Brüggemann, Odaléa Maria; Malfussi, Luciana Bihain Hagemann de
2018-01-01
Objective Describing the evaluation of the Structure, Process and Outcome of User Embracement with Risk Classification of an Emergency Care Unit from the perspective of physicians and nurses. Method An evaluative, descriptive, quantitative study developed in Santa Catarina. Data were collected using a validated and adapted instrument consisting of 21 items distributed in the dimensions of Structure (facilities), Process (activities and relationships in providing care) and Outcome (care effects). In the analysis, descriptive statistics and the Mean Ranking and Mean Score calculations were applied. Results The sample consisted of 37 participants. From the 21 evaluated items, 11 (52.4%) had a Mean Ranking between 3 and 4, and none of them reached the maximum ranking (5 points). "Prioritization of severe cases" and "Primary care according to the severity of the case" reached a higher Mean Ranking (4.5), while "Flowchart discussion" had the lowest Ranking (2.1). The dimensions of Structure, Process and Outcome reached mean scores of 23.9, 21.9 and 25.5, respectively, indicating a Precarious evaluation (17.5 to 26.1 points). Conclusion User Embracement with Risk Classification is precarious, especially regarding the Process which obtained a lower satisfaction level from the participants.
2016-09-12
Saturn's shadow stretched beyond the edge of its rings for many years after Cassini first arrived at Saturn, casting an ever-lengthening shadow that reached its maximum extent at the planet's 2009 equinox. This image captured the moment in 2015 when the shrinking shadow just barely reached across the entire main ring system. The shadow will continue to shrink until the planet's northern summer solstice, at which point it will once again start lengthening across the rings, reaching across them in 2019. Like Earth, Saturn is tilted on its axis. And, just as on Earth, as the sun climbs higher in the sky, shadows get shorter. The projection of the planet's shadow onto the rings shrinks and grows over the course of its 29-year-long orbit, as the angle of the sun changes with respect to Saturn's equator. This view looks toward the sunlit side of the rings from about 11 degrees above the ring plane. The image was taken in visible light with the Cassini spacecraft wide-angle camera on Jan. 16, 2015. The view was obtained at a distance of approximately 1.6 million miles (2.5 million kilometers) from Saturn. Image scale is about 90 miles (150 kilometers) per pixel. http://photojournal.jpl.nasa.gov/catalog/PIA20498
NASA Astrophysics Data System (ADS)
Bawa, Nupur; Jain, Vikrant; Shekhar, Shashank; Kumar, Niraj; Jyani, Vikas
2014-12-01
Understanding the controls on the morphological variability of river systems constitutes one of the fundamental questions in geomorphic investigation. Channel morphology is an important indicator of river processes and is of significance for mapping the hydrology-ecologic connectivity in a river system and for predicting the future trajectory of river health in response to external forcings. This paper documents the spatial morphological variability and its natural and anthropogenic controls for the Yamuna River, a major tributary of the Ganga River, India. The Yamuna River runs through a major urban centre i.e. Delhi National Capital Region. The Yamuna River was divided into eight geomorphically distinct reaches on the basis of the assemblages of geomorphic units and the association of landscape, valley and floodplain settings. The morphological variability was analysed through stream power distribution and sediment load data at various stations. Stream power distribution of the Yamuna River basin is characterised by a non-linear pattern that was used to distinguish (a) high energy ‘natural' upstream reaches, (b) ‘anthropogenically altered', low energy middle stream reaches, and (c) ‘rejuvenated' downstream reaches again with higher stream power. The relationship between stream power and channel morphology in these reaches was integrated with sediment load data to define the maximum flow efficiency (MFE) as the threshold for geomorphic transition. This analysis supports the continuity of river processes and the significance of a holistic, basin-scale approach rather than isolated local scale analysis in river studies.
Seasonal abundance of horse flies (Diptera: Tabanidae) from two locations in eastern Croatia.
Krcmar, Stjepan
2005-12-01
A total of 10,539 tabanid horse flies from 22 species and five genera was collected in the Tikves forest within the Kopacki rit Nature Park in eastern Croatia. Seasonal abundance was analyzed for the six most abundant species. Tabanus maculicornis, Tabanus tergestinus, and Haematopota pluvialis reached their highest peak abundance in the fourth week of June. Atylotus loewianus and Tabanus bromius reached their highest peak of abundance in the first week of August, whereas Tabanus sudeticus reached its maximum abundance in the third week of July. Horse flies also were collected once a week on the pasture at Petrijevci from mid-May to mid-September during 1993. Paired collections were made from a Malaise trap and from a horse by using a sweep net. A total of 2,867 tabanids belonging to 26 species was collected. The number of tabanids collected on horses was much higher than the total captured with Malaise traps. On their natural host (horse), 2.6 times more tabanids were collected than in the traps. Seasonal abundance was analyzed only for the eight most abundant species. Chrysops paralellogrammus, Tabanus autumnalis, Tabanus bromius, Tabanus tergestinus, Haematopota pluvialis, and Haematopota subcylindrica all reached their highest peak of abundance in the second week of July, whereas Tabanus maculicornis reached the maximal peak of abundance in the third week of June. Seasonal meteorological variability that occurs periodically from one year to another has a significant influence on the maximal peaks of tabanid abundance.
Temperature-dependent surface density of alkylthiol monolayers on gold nanocrystals
NASA Astrophysics Data System (ADS)
Liu, Xuepeng; Lu, Pin; Zhai, Hua; Wu, Yucheng
2018-03-01
Atomistic molecular dynamics (MD) simulations are performed to study the surface density of passivating monolayers of alkylthiol chains on gold nanocrystals at temperatures ranging from 1 to 800 K. The results show that the surface density of alkylthiol monolayer reaches a maximum value at near room temperature (200-300 K), while significantly decreases with increasing temperature in the higher temperature region (> 300 {{K}}), and slightly decreases with decreasing temperature at low temperature (< 200 {{K}}). We find that the temperature dependence of surface ligand density in the higher temperature region is attributed to the substantial ligand desorption induced by the thermal fluctuation, while that at low temperature results from the reduction in entropy caused by the change in the ordering of passivating monolayer. These results are expected helpful to understand the temperature-dependent surface coverage of gold nanocrystals.
Estimating potency for the Emax-model without attaining maximal effects.
Schoemaker, R C; van Gerven, J M; Cohen, A F
1998-10-01
The most widely applied model relating drug concentrations to effects is the Emax model. In practice, concentration-effect relationships often deviate from a simple linear relationship but without reaching a clear maximum because a further increase in concentration might be associated with unacceptable or distorting side effects. The parameters for the Emax model can only be estimated with reasonable precision if the curve shows sign of reaching a maximum, otherwise both EC50 and Emax estimates may be extremely imprecise. This paper provides a solution by introducing a new parameter (S0) equal to Emax/EC50 that can be used to characterize potency adequately even if there are no signs of a clear maximum. Simulations are presented to investigate the nature of the new parameter and published examples are used as illustration.
Effects of accuracy constraints on reach-to-grasp movements in cerebellar patients.
Rand, M K; Shimansky, Y; Stelmach, G E; Bracha, V; Bloedel, J R
2000-11-01
Reach-to-grasp movements of patients with pathology restricted to the cerebellum were compared with those of normal controls. Two types of paradigms with different accuracy constraints were used to examine whether cerebellar impairment disrupts the stereotypic relationship between arm transport and grip aperture and whether the variability of this relationship is altered when greater accuracy is required. The movements were made to either a vertical dowel or to a cross bar of a small cross. All subjects were asked to reach for either target at a fast but comfortable speed, grasp the object between the index finger and thumb, and lift it a short distance off the table. In terms of the relationship between arm transport and grip aperture, the control subjects showed a high consistency in grip aperture and wrist velocity profiles from trial to trial for movements to both the dowel and the cross. The relationship between the maximum velocity of the wrist and the time at which grip aperture was maximal during the reach was highly consistent throughout the experiment. In contrast, the time of maximum grip aperture and maximum wrist velocity of the cerebellar patients was quite variable from trial to trial, and the relationship of these measurements also varied considerably. These abnormalities were present regardless of the accuracy requirement. In addition, the cerebellar patients required a significantly longer time to grasp and lift the objects than the control subjects. Furthermore, the patients exhibited a greater grip aperture during reach than the controls. These data indicate that the cerebellum contributes substantially to the coordination of movements required to perform reach-to-grasp movements. Specifically, the cerebellum is critical for executing this behavior with a consistent, well-timed relationship between the transport and grasp components. This contribution is apparent even when accuracy demands are minimal.
A simple parameterization for the height of maximum ozone heating rate
NASA Astrophysics Data System (ADS)
Zhang, Feng; Hou, Can; Li, Jiangnan; Liu, Renqiang; Liu, Cuiping
2017-12-01
It is well-known that the height of the maximum ozone heating rate is much higher than the height of the maximum ozone concentration in the stratosphere. However, it lacks an analytical expression to explain it. A simple theoretical model has been proposed to calculate the height of maximum ozone heating rate and further understand this phenomenon. Strong absorption of ozone causes the incoming solar flux to be largely attenuated before reaching the location of the maximum ozone concentration. By comparing with the exact radiative transfer calculations, the heights of the maximum ozone heating rate produced by the theoretical model are generally very close to the true values. When the cosine of solar zenith angle μ0 = 1.0 , in US Standard atmosphere, the heights of the maximum ozone heating rate by the theoretical model are 41.4 km in the band 0.204-0.233 μm, 47.9 km in the band 0.233-0.270 μm, 44.5 km in the band 0.270-0.286 μm, 37.1 km in the band 0.286-0.303 μm, and 30.2 km in the band 0.303-0.323 μm, respectively. The location of the maximum ozone heating rate is sensitive to the solar spectral range. In band 1, the heights of the maximum ozone heating rate by the theoretical model are 52.3 km for μ0 = 0.1 , 47.1 km for μ0 = 0.3 , 44.6 km for μ0 = 0.5 , 43.1 km for μ0 = 0.7 , 41.9 km for μ0 = 0.9 , 41.4 km for μ0 = 1.0 in US Standard atmosphere, respectively. This model also illustrates that the location of the maximum ozone heating rate is sensitive to the solar zenith angle.
Comparison of masticatory performance and tongue pressure between children and young adults.
Fujita, Yuko; Ichikawa, Maika; Hamaguchi, Ayako; Maki, Kenshi
2018-04-01
The aims of the present study were to evaluate whether there are significant differences in masticatory performance by gender and dental stage. We also determined the factors directly associated with the masticatory performance in children, and those directly associated with masticatory performance in young adults. The study included 180 subjects, ranging in age from 6 to 12 years or 20 to 33 years. The subjects were divided into three groups according to the Hellman developmental stage (III A, III B, or VA); the groups were the subdivided according to gender. The body mass index (BMI), maximum tongue pressure, and sum of decayed, missing, and filled teeth (DMFT) were determined in all subjects. To investigate masticatory performance, the total number and maximum projected area of chewed particles of the jelly materials were measured. Masticatory performance had the highest values at Stage VA in both males and females. Regarding the maximum tongue pressure in females, Stage III B had the highest value of all stages. Multiple regression analysis showed that masticatory performance was associated with DMFT index, maximum tongue pressure, and BMI in children. Among young adults, masticatory performance was associated with DMFT index and maximum tongue pressure. Better masticatory performance is directly associated with better dental status, a higher BMI, and tongue pressure in schoolchildren. Additionally, masticatory performance was well-correlated with tongue pressure in young adults, although maximum tongue pressure reached its peak before Stage VA in females. We suggest that females need training with respect to tongue pressure, by the mixed dentition stage.
NASA Technical Reports Server (NTRS)
Rodgers, Edward B.; Adler, Robert F.; Pierce, Harold F.; Einaudi, Franco (Technical Monitor)
2000-01-01
The tropical cyclone rainfall climatology study that was performed for the North Pacific was extended to the North Atlantic. Similar to the North Pacific tropical cyclone study, mean monthly rainfall within 444 km of the center of the North Atlantic tropical cyclones (i.e., that reached storm stage and greater) was estimated from passive microwave satellite observations during, an eleven year period. These satellite-observed rainfall estimates were used to assess the impact of tropical cyclone rainfall in altering the geographical, seasonal, and inter-annual distribution of the North Atlantic total rainfall during, June-November when tropical cyclones were most abundant. The main results from this study indicate: 1) that tropical cyclones contribute, respectively, 4%, 3%, and 4% to the western, eastern, and entire North Atlantic; 2) similar to that observed in the North Pacific, the maximum in North Atlantic tropical cyclone rainfall is approximately 5 - 10 deg poleward (depending on longitude) of the maximum non-tropical cyclone rainfall; 3) tropical cyclones contribute regionally a maximum of 30% of the total rainfall 'northeast of Puerto Rico, within a region near 15 deg N 55 deg W, and off the west coast of Africa; 4) there is no lag between the months with maximum tropical cyclone rainfall and non-tropical cyclone rainfall in the western North Atlantic, while in the eastern North Atlantic, maximum tropical cyclone rainfall precedes maximum non-tropical cyclone rainfall; 5) like the North Pacific, North Atlantic tropical cyclones Of hurricane intensity generate the greatest amount of rainfall in the higher latitudes; and 6) warm ENSO events inhibit tropical cyclone rainfall.
Ectoparasites of a population of urban gray squirrels in northern Florida.
Wilson, N A; Telford, S R; Forrester, D J
1991-05-01
Ectoparasites infesting a population of urban gray squirrels (Sciurus carolinensis Gmelin) in northern Florida were collected monthly during 1974. Eleven species were identified: one flea (Orchopeas howardi (Baker], three suckling lice (Enderleinellus longiceps Kellogg & Ferris, Hoplopleura sciuricola Ferris, and Neohaematopinus sciuri Jancke), one tick (Dermacentor variabilis Say), two mesostigmatid (gamasid) mites (Androlaelaps casalis (Berlese) and A. fahrenholzi (Berlese], and four chiggers (Eutrombicula alfreddugesi (Oudemans), E. splendens (Ewing), Leptotrombidium peromysci Vercammen-Grandjean & Langston, and Parasecia gurneyi (Ewing]. The flea and three suckling lice represent core species of ectoparasites for the gray squirrel; the remainder are probably satellite species. Only E. longiceps varied significantly in prevalence or intensity of infestation among host age groups; subadult squirrels had higher intensities than adults. Peak prevalence of O. howardi occurred in January and attained maximum intensity in March, whereas both prevalance and intensity were minimum in August. Prevalence of H. sciuricola was maximum in November and remained at similar levels through June. It then declined significantly to its minimum in September-October. Intensity of infestation, however, was greatest in August, September, and January. Maximum prevalence of N. sciuri occurred from January to March and was minimum in September; intensity of infestation reached maxima in January, June, and August.
NASA Astrophysics Data System (ADS)
Bradu, Adrian; Marques, Manuel J.; Bouchal, Petr; Podoleanu, Adrian Gh.
2013-03-01
The purpose of this study was to show how to favorably mix two e_ects to improve the sensitivity with depth in Fourier domain optical coherence tomography (OCT): Talbot bands (TB) and Gabor-based fusion (GF) technique. TB operation is achieved by directing the two beams, from the object arm and from the reference arm in the OCT interferometer, along parallel separate paths towards the spectrometer. By changing the lateral gap between the two beams in their path towards the spectrometer, the position for the maximum sensitivity versus the optical path difference in the interferometer is adjusted. For five values of the focus position, the gap between the two beams is readjusted to reach maximum sensitivity. Then, similar to the procedure employed in the GF technique, a composite image is formed by edging together the parts of the five images that exhibited maximum brightness. The combined procedure, TB/GF is examined for four different values of the beam diameters of the two beams. Also we demonstrate volumetric FD-OCT images with mirror term attenuation and sensitivity profile shifted towards higher OPD values by applying a Talbot bands configuration.
Selected important fragrance sensitizers in perfumes--current exposures.
Rastogi, Suresh Chandra; Johansen, Jeanne Duus; Bossi, Rossana
2007-04-01
Contact allergy to fragrance ingredients is frequent. Recommendations and regulations of some of the most frequent and potent fragrance allergens have recently been introduced. To investigate current exposures to 4 important fragrance allergens in hydroalcoholic cosmetic products. 25 popular perfume products of Danish as well as international brands were purchased from the Danish retail market. Contents of 4 important fragrance allergens, isoeugenol, hydroxy-iso-hexyl 3-cyclohexene carboxaldehyde (HICC, Lyral), were determined by gas chromatography-mass spectrometry, and atranol and chloro-atranol were determined by liquid chromatography-tandem mass spectrometry. Isoeugenol was found in 56%, HICC in 72%, atranol in 59%, and chloro-atranol in 36% of the 22 eau de toilette/eau de parfum products. The concentrations of isoeugenol were, in all products, below the recommended maximum concentration of 0.02%. HICC reached a maximum of 0.2%, which is 10-fold higher than maximum tolerable concentration considered safe by the EU Scientific Committee. The median concentrations of atranol and chloro-atranol in the investigated products were similar to those found in similar products in 2003. A significant decrease in the frequency of presence of chloro-atranol in the products was observed. There is still a wide-spread exposure to potent fragrance allergens in perfumes.
The shouted voice: A pilot study of laryngeal physiology under extreme aerodynamic pressure.
Lagier, Aude; Legou, Thierry; Galant, Camille; Amy de La Bretèque, Benoit; Meynadier, Yohann; Giovanni, Antoine
2017-12-01
The objective was to study the behavior of the larynx during shouted voice production, when the larynx is exposed to extremely high subglottic pressure. The study involved electroglottographic, acoustic, and aerodynamic analyses of shouts produced at maximum effort by three male participants. Under a normal speaking voice, the voice sound pressure level (SPL) is proportional to the subglottic pressure. However, when the subglottic pressure reached high levels, the voice SPL reached a maximum value and then decreased as subglottic pressure increased further. Furthermore, the electroglottographic signal sometimes lost its periodicity during the shout, suggesting irregular vocal fold vibration.
Research on disposal of copper(II)-containing wastewater by secondary strontium residue
NASA Astrophysics Data System (ADS)
Qing, Duowen; Xu, Longjun; Cui, Caixi
2018-01-01
Secondary strontium residue (SSR) was used as absorbent to remove Cu2+ in solution and the effects of experimental conditions on absorption of Cu2+ were investigated. The results showed that the absorption process reached balance in around 40 min. The absorption capacity achieved the maximum when PH value reached 6, and the maximum adsorption of Cu2+-containing wastewater by secondary strontium residue was 5.46 mg/g. Removal ratio of Cu2+ was in relation to initial concentration of Cu2+ in solution. Adsorptive process tallied with Langmuir Isothermal adsorption model.
Emission of a Dual-Fuel Turbocharged Compression Ignition Engine
NASA Astrophysics Data System (ADS)
Rózycki, Andrzej
2012-02-01
The paper describes the results of a four-cylinder dual fuel turbocharged compression ignition engine. The aim of the study was to determine the maximum CNG share in thefuel mixture delivered into the cylinder. Analysis of the investigation results showed that the CNG energy share in the fuel charge delivered into the cylinder can reach 45%. At that level of CNG energy share a 15% reduction in maximum torque is achieved in comparison with the standard fuelling. The unburnt hydrocarbon emission increases significantly. Emissions of other principal pollutants reach values comparable with those obtained at standard fuelling.
DISPERSION OF RADIOACTIVE ISOTOPES IN THE SOIL BY EARTHWORMS (in Russian)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Peredel'skii, A.A.; Shain, S.S.; Karavyanskii, N.S.
1960-11-01
The effects of earthworms on the distribution and migration of radioisotopes in contaminated earth were investigated. Data on the mean Ca/sup 45/ and Sr/sup 90/ activity of a single worm and its coprolith in contaminated soil are tabulated. It is shown that the specific radioactivity in the earthworm quickly reaches a maximum and remains unchanged during further inhabitance in the contuminated soil. The specific activity of the earthworm can reach that of the soil; however, after leaving the contuminated area, the activity is rapidly reduced in the worm. The specific activity of the earthworm coprolith is close to that ofmore » the body; sometimes it exceeds the activity of both the body and the soil due to uptake of organic material of higher radioactivity. The experiment shows that the influence of earthworms on dissemination of shont-lifs isotopes is negligible but that with long-life isotopes it may be more noticeable. (R.V.J.)« less
Sariçoban, Cemalettin; Yilmaz, Mustafa Tahsin; Karakaya, Mustafa; Tiske, Sümeyra Sultan
2010-01-01
The effect of sunflower head pith on the functional properties of emulsions was studied by using a model system. Oil/water (O/W) model emulsion systems were prepared from fresh and frozen beef by the addition of the pith at five concentrations. Emulsion capacity (EC), stability (ES), viscosity (EV), colour and flow properties of the prepared model system emulsions were analyzed. The pith addition increased the EC and ES and the highest EC and ES values were reached when 5% of pith added; however, further increase in the pith concentration caused an inverse trend in these values. Fresh beef emulsions had higher EC and ES values than did frozen beef emulsions. One percent pith concentration was the critic level for the EV values of fresh beef emulsions. EV values of the emulsions reached a maximum level at 5% pith level, followed by a decrease at 7% pit level.
Flickinger, Allison; Christensen, Eric D.
2017-01-01
The Little Blue River in Jackson County, Missouri, was listed as impaired in 2012 due to Escherichia coli (E. coli) from urban runoff and storm sewers. A study was initiated to characterize E. coli concentrations and loads to aid in the development of a total maximum daily load implementation plan. Longitudinal sampling along the stream revealed spatial and temporal variability in E. coli loads. Regression models were developed to better represent E. coli variability in the impaired reach using continuous hydrologic and water-quality parameters as predictive parameters. Daily loads calculated from main-stem samples were significantly higher downstream compared to upstream even though there was no significant difference between the upstream and downstream measured concentrations and no significant conclusions could be drawn from model-estimated loads due to model-associated uncertainty. Increasing sample frequency could decrease the bias and increase the accuracy of the modeled results.
Effect of a virtual reality-enhanced exercise protocol after coronary artery bypass grafting.
Chuang, Tien-Yow; Sung, Wen-Hsu; Chang, Hwa-Ann; Wang, Ray-Yau
2006-10-01
Virtual reality (VR) technology has gained importance in many areas of medicine. Knowledge concerning the application and the influence of VR-enhanced exercise programs is limited for patients receiving coronary artery bypass grafting. The purpose of this study was to evaluate the effect of a virtual "country walk" on the number of sessions necessary to reach cardiac rehabilitation goals in patients undergoing coronary artery bypass grafting. Twenty subjects who were seen for cardiac rehabilitation between January and June 2004 comprised the study sample. The protocol for this study included an initial maximum graded exercise tolerance test, given to determine the subsequent training goals for the subject, followed by biweekly submaximal endurance training sessions. All subjects were assigned by lot to 1 of 2 submaximal endurance training programs, one (group 2) with and the other (group 1) without the added VR environment. In all other respects, the 2 programs were identical. Each training session lasted for 30 minutes and was carried out twice per week for about 3 months. The primary outcome measures were maximum load during the work sessions, target oxygen consumption, target heart rate (beats per minute), and number of training sessions required to reach rehabilitation goals. By the end of 20 training sessions, only 4 of the 10 control subjects had reached the heart rate target goal of 85% their maximum heart rate. In contrast, 9 of the 10 subjects in the VR program had attained this goal by 9 or fewer training sessions. When target metabolic cost (75% peak oxygen consumption) was used as the training goal, all 10 subjects in the VR program had reached this target after 2 training sessions (or, in some cases, 1 training session), but not until training session 15 did a cumulative number of 9 control subjects reach this goal. These study outcomes clearly support the notion that incorporating a VR environment into cardiac rehabilitation programs will accelerate maximum recovery of patients' cardiovascular function.
Maximum Range of a Projectile Thrown from Constant-Speed Circular Motion
ERIC Educational Resources Information Center
Poljak, Nikola
2016-01-01
The problem of determining the angle ? at which a point mass launched from ground level with a given speed v[subscript 0] will reach a maximum distance is a standard exercise in mechanics. There are many possible ways of solving this problem, leading to the well-known answer of ? = p/4, producing a maximum range of D[subscript max] = v[superscript…
Duration of shoot elongation in Scots pine varies within the crown and between years.
Schiestl-Aalto, Pauliina; Nikinmaa, Eero; Mäkelä, Annikki
2013-10-01
Shoot elongation in boreal and temperate trees typically follows a sigmoid pattern where the onset and cessation of growth are related to accumulated effective temperature (thermal time). Previous studies on leader shoots suggest that while the maximum daily growth rate depends on the availability of resources to the shoot, the duration of the growth period may be an adaptation to long-term temperature conditions. However, other results indicate that the growth period may be longer in faster growing lateral shoots with higher availability of resources. This study investigates the interactions between the rate of elongation and the duration of the growth period in units of thermal time in lateral shoots of Scots pine (Pinus sylvestris). Length development of 202 lateral shoots were measured approximately three times per week during seven growing seasons in 2-5 trees per year in a mature stand and in three trees during one growing season in a sapling stand. A dynamic shoot growth model was adapted for the analysis to determine (1) the maximum growth rate and (2) the thermal time reached at growth completion. The relationship between those two parameters and its variation between trees and years was analysed using linear mixed models. The shoots with higher maximum growth rate within a crown continued to grow for a longer period in any one year. Higher July-August temperature of the previous summer implied a higher requirement of thermal time for growth completion. The results provide evidence that the requirement of thermal time for completion of lateral shoot extension in Scots pine may interact with resource availability to the shoot both from year to year and among shoots in a crown each year. If growing season temperatures rise in the future, this will affect not only the rate of shoot growth but its duration also.
NASA Astrophysics Data System (ADS)
Nath, D. C. D.; Bandyopadhyay, S.; Campbell, J.; Yu, A.; Blackburn, D.; White, C.
2010-12-01
Composite films of poly(vinyl alcohol) (PVA) reinforced with 5, 10, 15, 20 and 25 wt.% surface-coated fly ash by surfactant, sodium lauryl sulphate (SLS-FA) along with 1 wt.% cross-linking agent, glutaraldehyde (GLA) were prepared by aqueous casting method. The tensile strengths of the composite films were increased proportionally with the addition of SLS-FA. The maximum 75% higher strength of the composite with 20 wt.% was achieved compared to that of neat PVA. The modulus of the composites was also increased proportionally with SLS-FA and the maximum 218% reached in composite with 20 wt.%, but the strain at break was decreased with addition of SLS-FA. Changes in FTIR spectra reflect the chemical and/or physical bonding in the ternary PVA, SLS-FA and GLA component systems. In the study of surface morphology, the connectivity was visualized in SEM images along with interstitial voids. The films with SLS-FA show 53% smoother surface calculated with AFM compared to unmodified FA composite films.
Study on luminescence characteristics of blue OLED with phosphor-doped host-guest structure
NASA Astrophysics Data System (ADS)
Wang, Zhen; Liu, Fei; Zheng, Xin; Chen, Ai; Xie, Jia-feng; Zhang, Wen-xia
2018-05-01
In this study, we design and fabricate phosphor-doped host-guest structure organic light-emitting diodes (OLEDs), where the blue-ray iridium complex electrophosphorescent material FIrpic acts as object material. Properties of the device can be accommodated by changing the host materials, dopant concentration and thickness of the light-emitting layer. The study shows that the host material N,N'-dicarbazolyl-3,5-benzene (mCP) has a higher triplet excited state energy level, which can effectively prevent FIrpic triplet excited state energy backtracking to host material, thus the luminous efficiency is improved. When mCP is selected as the host material, the thickness of the light-emitting layer is 30 nm and the dopant concentration is 8 wt%, the excitons can be effectively confined in the light-emitting region. As a result, the maximum current efficiency and the maximum brightness of the blue device can reach 15.5 cd/A and 7 196.3 cd/m2, respectively.
Doping reaction of PH3 and B2H6 with Si(100)
NASA Astrophysics Data System (ADS)
Yu, Ming L.; Vitkavage, D. J.; Meyerson, B. S.
1986-06-01
The reaction of phosphine PH3 and diborane B2H6 on Si(100) surfaces was studied by surface analytical techniques in relation to the in situ doping process in the chemical vapor deposition of silicon. Phosphine chemisorbs readily either nondissociatively at room temperature or dissociatively with the formation of silicon-hydrogen bonds at higher temperatures. Hydrogen can be desorbed at temperatures above 400 °C to generate a phosphorus layer. Phosphorus is not effective in shifting the Fermi level until the coverage reaches 2×1014/cm2. A maximum shift of 0.45 eV toward the conduction band was observed. In contrast, diborane has a very small sticking coefficient and the way to deposit boron is to decompose diborane directly on the silicon surface at temperatures above 600 °C. Boron at coverages less than 2×1014/cm2 is very effective in shifting the Fermi level toward the valence band and a maximum change of 0.4 eV was observed.
Zhao, Lei; Cao, Guang-Li; Sheng, Tao; Ren, Hong-Yu; Wang, Ai-Jie; Zhang, Jian; Zhong, Ying-Juan; Ren, Nan-Qi
2017-11-01
Mycelia pellets were employed as biological carrier in a continuous stirred tank reactor to reduce biomass washout and enhance hydrogen production from cornstalk hydrolysate. Hydraulic retention time (HRT) and influent substrate concentration played critical roles on hydrogen production of the bioreactor. The maximum hydrogen production rate of 14.2mmol H 2 L -1 h -1 was obtained at optimized HRT of 6h and influent concentration of 20g/L, 2.6 times higher than the counterpart without mycelia pellets. With excellent immobilization ability, biomass accumulated in the reactor and reached 1.6g/L under the optimum conditions. Upon further energy conversion analysis, continuous hydrogen production with mycelia pellets gave the maximum energy conversion efficiency of 17.8%. These results indicate mycelia pellet is an ideal biological carrier to improve biomass retention capacity of the reactor and enhance hydrogen recovery efficiency from lignocellulosic biomass, and meanwhile provides a new direction for economic and efficient hydrogen production process. Copyright © 2017 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Maqueo, P. D. G.; Maier, M.; Evans, M. D. G.; Coulombe, S.; Bergthorson, J. M.
2018-04-01
The operation of a nanosecond repetitively pulsed discharge for partial oxidation of CH4 is characterized at atmospheric pressure and room temperature. Two regimes are observed: diffuse and filamentary. The first is a low power regime, characterized by low rotational temperatures around 400 K. The second is much more energetic with rotational temperatures close to 600 K. Both have vibrational temperatures of at least 10 times their rotational temperatures. The average electron number density was determined to be 8.9×1015 and 4.0×1017 cm-3, respectively, showing an increase in the ionization fraction in the more powerful filamentary regime. Results of CH4 conversion to H2, CO, CO2 and C2H6 are presented for the filamentary regime, while the diffuse regime shows no measurable conversion ability. As expected, oxidative mixtures show higher conversion ability than pure CH4. A maximum conversion efficiency of 26.3% and a maximum energy efficiency of 19.7% were reached for the oxidative mixtures.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pratama, R.; Kurniawan, B., E-mail: bkuru07@gmail.com; Manaf, A.
2016-04-19
A detail work was conducted in order to investigate effect of various sintering temperature on resistivity behavior and its relation with the magneto-resistance effect of La{sub 0.67}Ba{sub 0.33}MnO{sub 3} (LBMO). The LBMO samples were synthesized using solid state reaction. Characterization using X-ray diffraction shows that all LBMO samples have a single phase for each variation. Variation of sintering temperature on the LBMO samples affects its lattice parameters. The resistivity measurement in an absence and under applied magnetic field resulted in a highly significant different values. In one of the sintering temperature variation of LBMO, an increasing resistivity had shown atmore » a low temperature and had reached its maximum value at a specific temperature, and then the resistivity decreases to the lowest value near the room temperature. Similar result observed at higher varieties of sintering temperature but with significant lower maximum resistivity.« less
Asymptotic properties of a bold random walk
NASA Astrophysics Data System (ADS)
Serva, Maurizio
2014-08-01
In a recent paper we proposed a non-Markovian random walk model with memory of the maximum distance ever reached from the starting point (home). The behavior of the walker is different from the simple symmetric random walk only when she is at this maximum distance, where, having the choice to move either farther or closer, she decides with different probabilities. If the probability of a forward step is higher than the probability of a backward step, the walker is bold and her behavior turns out to be superdiffusive; otherwise she is timorous and her behavior turns out to be subdiffusive. The scaling behavior varies continuously from subdiffusive (timorous) to superdiffusive (bold) according to a single parameter γ ∈R. We investigate here the asymptotic properties of the bold case in the nonballistic region γ ∈[0,1/2], a problem which was left partially unsolved previously. The exact results proved in this paper require new probabilistic tools which rely on the construction of appropriate martingales of the random walk and its hitting times.
Accessible Buildings for People with Walking and Reaching Limitations.
ERIC Educational Resources Information Center
Steinfeld, Edward; And Others
Research was reviewed and conducted regarding the accessibility of buildings for physically disabled persons. Data was produced regarding anthropometrics (eye level and reach limits for ambulant, semiambulant, and wheelchair bound persons); wheelchair maneuvers; speed and distance (maximum travel distances for people with limitations of stamina);…
Satellite Observations of Glacier Surface Velocities in Southeast Alaska
NASA Astrophysics Data System (ADS)
Elliott, J.; Melkonian, A. K.; Pritchard, M. E.
2012-12-01
Glaciers in southeast Alaska are undergoing rapid changes and are significant contributors to sea level rise. A key to understanding the ice dynamics is knowledge of the surface velocities, which can be used with ice thickness measurements to derive mass flux rates. For many glaciers in Alaska, surface velocity estimates either do not exist or are based on data that are at least a decade old. Here we present updated maps of glacier surface velocities in southeast Alaska produced through a pixel tracking technique using synthetic aperture radar data and high-resolution optical imagery. For glaciers with previous velocity estimates, we will compare the results and discuss possible implications for ice dynamics. We focus on Glacier Bay and the Stikine Icefield, which contain a number of fast-flowing tidewater glaciers including LeConte, Johns Hopkins, and La Perouse. For the Johns Hopkins, we will also examine the influence a massive landslide in June 2012 had on flow dynamics. Our velocity maps show that within Glacier Bay, the highest surface velocities occur on the tidewater glaciers. La Perouse, the only Glacier Bay glacier to calve directly into the Pacific Ocean, has maximum velocities of 3.5 - 4 m/day. Johns Hopkins Glacier shows 4 m/day velocities at both its terminus and in its upper reaches, with lower velocities of ~1-3 m/day in between those two regions. Further north, the Margerie Glacier has a maximum velocity of ~ 4.5 m/day in its upper reaches and a velocity of ~ 2 m/day at its terminus. Along the Grand Pacific terminus, the western terminus fed by the Ferris Glacier displays velocities of about 1 m/day while the eastern terminus has lower velocities of < 0.5 m/day. The lake terminating glaciers along the Pacific coast have overall lower surface velocities, but they display complex flow patterns. The Alsek Glacier displays maximum velocities of 2.5 m/day above where it divides into two branches. Velocities at the terminus of the northern branch reach 1 m/day while the terminus of the southern branch moves about 2 m/day. Grand Plateau Glacier also divides into two main branches, with a northern branch displaying peak velocities of 1.5 m/day and a southern branch flowing at a rate of 1 m/day. The Stikine Icefield contains a number of large tidewater glaciers showing maximum velocities near their termini. At the terminus of the South Sawyer Glacier, velocities reach a peak of about 2 m/day. Along the terminus of the Dawes Glacier, velocities reach 3.5 m/day. The Baird Glacier displays lower velocities of 1-1.5 m/day. LeConte Glacier has 2-3 m/day velocities in its upper regions with higher velocities near its terminus. In contrast to the pattern shown by the surrounding glaciers, the Great Glacier has a peak velocity of 2 m/day in the upper portion of the glacier and a velocity of only 0.5 m/day near its terminus.
Growth and Maximum Size of Tiger Sharks (Galeocerdo cuvier) in Hawaii
Meyer, Carl G.; O'Malley, Joseph M.; Papastamatiou, Yannis P.; Dale, Jonathan J.; Hutchinson, Melanie R.; Anderson, James M.; Royer, Mark A.; Holland, Kim N.
2014-01-01
Tiger sharks (Galecerdo cuvier) are apex predators characterized by their broad diet, large size and rapid growth. Tiger shark maximum size is typically between 380 & 450 cm Total Length (TL), with a few individuals reaching 550 cm TL, but the maximum size of tiger sharks in Hawaii waters remains uncertain. A previous study suggested tiger sharks grow rather slowly in Hawaii compared to other regions, but this may have been an artifact of the method used to estimate growth (unvalidated vertebral ring counts) compounded by small sample size and narrow size range. Since 1993, the University of Hawaii has conducted a research program aimed at elucidating tiger shark biology, and to date 420 tiger sharks have been tagged and 50 recaptured. All recaptures were from Hawaii except a single shark recaptured off Isla Jacques Cousteau (24°13′17″N 109°52′14″W), in the southern Gulf of California (minimum distance between tag and recapture sites = approximately 5,000 km), after 366 days at liberty (DAL). We used these empirical mark-recapture data to estimate growth rates and maximum size for tiger sharks in Hawaii. We found that tiger sharks in Hawaii grow twice as fast as previously thought, on average reaching 340 cm TL by age 5, and attaining a maximum size of 403 cm TL. Our model indicates the fastest growing individuals attain 400 cm TL by age 5, and the largest reach a maximum size of 444 cm TL. The largest shark captured during our study was 464 cm TL but individuals >450 cm TL were extremely rare (0.005% of sharks captured). We conclude that tiger shark growth rates and maximum sizes in Hawaii are generally consistent with those in other regions, and hypothesize that a broad diet may help them to achieve this rapid growth by maximizing prey consumption rates. PMID:24416287
Growth and maximum size of tiger sharks (Galeocerdo cuvier) in Hawaii.
Meyer, Carl G; O'Malley, Joseph M; Papastamatiou, Yannis P; Dale, Jonathan J; Hutchinson, Melanie R; Anderson, James M; Royer, Mark A; Holland, Kim N
2014-01-01
Tiger sharks (Galecerdo cuvier) are apex predators characterized by their broad diet, large size and rapid growth. Tiger shark maximum size is typically between 380 & 450 cm Total Length (TL), with a few individuals reaching 550 cm TL, but the maximum size of tiger sharks in Hawaii waters remains uncertain. A previous study suggested tiger sharks grow rather slowly in Hawaii compared to other regions, but this may have been an artifact of the method used to estimate growth (unvalidated vertebral ring counts) compounded by small sample size and narrow size range. Since 1993, the University of Hawaii has conducted a research program aimed at elucidating tiger shark biology, and to date 420 tiger sharks have been tagged and 50 recaptured. All recaptures were from Hawaii except a single shark recaptured off Isla Jacques Cousteau (24°13'17″N 109°52'14″W), in the southern Gulf of California (minimum distance between tag and recapture sites = approximately 5,000 km), after 366 days at liberty (DAL). We used these empirical mark-recapture data to estimate growth rates and maximum size for tiger sharks in Hawaii. We found that tiger sharks in Hawaii grow twice as fast as previously thought, on average reaching 340 cm TL by age 5, and attaining a maximum size of 403 cm TL. Our model indicates the fastest growing individuals attain 400 cm TL by age 5, and the largest reach a maximum size of 444 cm TL. The largest shark captured during our study was 464 cm TL but individuals >450 cm TL were extremely rare (0.005% of sharks captured). We conclude that tiger shark growth rates and maximum sizes in Hawaii are generally consistent with those in other regions, and hypothesize that a broad diet may help them to achieve this rapid growth by maximizing prey consumption rates.
[Reflectance of sea ice in Liaodong Bay].
Xu, Zhan-tang; Yang, Yue-zhong; Wang, Gui-fen; Cao, Wen-xi; Kong, Xiang-peng
2010-07-01
In the present study, the relationships between sea ice albedo and the bidirectional reflectance distribution in Liaodong Bay were investigated. The results indicate that: (1) sea ice albedo alpha(lambda) is closely related to the components of sea ice, the higher the particulate concentration in sea ice surface is, the lower the sea ice albedo alpha(lambda) is. On the contrary, the higher the bubble concentration in sea ice is, the higher sea ice albedo alpha(lambda) is. (2) Sea ice albedo alpha(lambda) is similar to the bidirectional reflectance factor R(f) when the probe locates at nadir. The R(f) would increase with the increase in detector zenith theta, and the correlation between R(f) and the detector azimuth would gradually increase. When the theta is located at solar zenith 63 degrees, the R(f) would reach the maximum, and the strongest correlation is also shown between the R(f) and the detector azimuth. (3) Different types of sea ice would have the different anisotropic reflectance factors.
Multiscale calculations of thermoelectric properties of n-type Mg2Si1-xSnx solid solutions
NASA Astrophysics Data System (ADS)
Tan, X. J.; Liu, W.; Liu, H. J.; Shi, J.; Tang, X. F.; Uher, C.
2012-05-01
The band structure of Mg2Si1-xSnx solid solutions with 0.250 ⩽ x ⩽ 0.875 is calculated using the first-principles pseudopotential method. It is found that the low-lying light and heavy conduction bands converge and the effective mass reaches a maximum value near x = 0.625. Using the semiclassical Boltzmann transport theory and relaxation-time approximation, we find that the system with x = 0.625 exhibits both higher Seebeck coefficient and higher electrical conductivity than other solid solutions at intermediate temperatures. By fitting first-principles total energy calculations, a modified Morse potential is constructed, which is used to predicate the lattice thermal conductivity via equilibrium molecular dynamics simulations. Due to relatively higher power factor and lower thermal conductivity, the Mg2Si0.375Sn0.625 is found to exhibit enhanced thermoelectric performance at 800 K, and additional Sb doping is considered in order to make a better comparison with experiment results.
Youth Baseball Pitching Mechanics: A Systematic Review.
Thompson, Samuel F; Guess, Trent M; Plackis, Andreas C; Sherman, Seth L; Gray, Aaron D
Pitching injuries in youth baseball are increasing in incidence. Poor pitching mechanics in young throwers have not been sufficiently evaluated due to the lack of a basic biomechanical understanding of the "normal" youth pitching motion. To provide a greater understanding of the kinetics and kinematics of the youth baseball pitching motion. PubMed, MEDLINE, and SPORTDiscus databases were searched from database inception through February 2017. A total of 10 biomechanical studies describing youth pitching mechanics were included. Systematic review. Level 3. Manual extraction and compilation of demographic, methodology, kinetic, and kinematic variables from the included studies were completed. In studies of healthy youth baseball pitchers, progressive external rotation of the shoulder occurs throughout the start of the pitching motion, reaching a maximum of 166° to 178.2°, before internally rotating throughout the remainder of the cycle, reaching a minimum of 13.2° to 17°. Elbow valgus torque reaches the highest level (18 ± 4 N·m) just prior to maximum shoulder external rotation and decreases throughout the remainder of the pitch cycle. Stride length is 66% to 85% of pitcher height. In comparison with a fastball, a curveball demonstrates less elbow varus torque (31.6 ± 15.3 vs 34.8 ± 15.4 N·m). Multiple studies show that maximum elbow valgus torque occurs just prior to maximum shoulder external rotation. Forces on the elbow and shoulder are greater for the fastball than the curveball.
Tight swimming trunks to prevent post scrotal surgery: an experimental justification.
Al-Abed, Yahya A; Carr, Thomas W
2013-01-01
To conduct a study to measure the pressure effects of the different scrotal supports applied on a simulated expanding scrotal hematoma. We created a model of an expanding hematoma with simultaneous pressure recording using a urodynamics system. Pressures were recorded independently first without application of any support. Then, three types of scrotal supports were tested, including Euron Net Knickers, scrotal suspensory bandage, and tight swimming trunks brand Speedo® brief and shorts. Subsequent pressures were recorded using the model created, which was applied inside the supports worn by two male volunteers A and B. Without any external compression, the pressure inside the simulated expanding hematoma "balloon" reached a maximum of 15 cmH2O. The pressures measured whilst wearing "Netelast knickers" in both subjects A and B reached a maximum of 15 cmH2O suggesting that this garment exerted no measurable compression. The suspensory scrotal support was then tested in both subjects. As the balloon started to fill with saline, the simulated hematoma pushed the scrotal support forward resulting in falling of the balloon outside the scrotal support. Subsequently, Speedo® briefs and shorts were tested. With Speedo® briefs, maximum filling pressures of 49 cmH2O and 40 cmH2O were reached in subjects A and B, respectively. When using Speedo® shorts, however, maximum pressures of 55 cmH2O in subject A and 54 cmH2O in subject B were reached at the end of the balloon filling to 300 mL of saline. The use of tight swimming trunks (Speedo®) has led to satisfactory results in the prevention of hematoma post scrotal surgery.
NASA Astrophysics Data System (ADS)
Zhang, L. M.; Hu, J. Y.; Wu, Z. H.; Luo, E. C.; Xu, J. Y.; Bi, T. J.
2015-07-01
This article introduces a multi-stage heat-driven thermoacoustic cryocooler capable of reaching cooling capacity about 1 kW at liquefied natural gas temperature range without any moving mechanical parts. The cooling system consists of an acoustically resonant double-acing traveling wave thermoacoustic heat engine and three identical pulse tube coolers. Unlike other traditional traveling wave thermoacoustic heat engines, the acoustically resonant double-acting thermoacoustic heat engine is a closed-loop configuration consists of three identical thermoacoustic conversion units. Each pulse tube cooler is bypass driven by one thermoacoustic heat engine unit. The device is acoustically completely symmetric and therefore "self-matching" for efficient traveling-wave thermoacoustic conversion. In the experiments, with 7 MPa helium gas as working gas, when the heating temperature reaches 918 K, total cooling capacity of 0.88 kW at 110 K is obtained with a resonant frequency of about 55 Hz. When the heating temperature is 903 K, a maximum total cooling capacity at 130 K of 1.20 kW is achieved, with a thermal-to-cold exergy efficiency of 8%. Compared to previously developed heat-driven thermoacoustic cryocoolers, this device has higher thermal efficiency and higher power density. It shows a good prospect of application in the field of natural gas liquefaction and recondensation.
Zheng, Weifa; Campbell, Bradley S; McDougall, Barbara M; Seviour, Robert J
2008-11-01
Aureobasidium pullulans produced pullulan and melanin when grown in medium containing low nitrate levels. With high nitrate concentrations, however, this fungus produced a mixture of exopolysaccharides (EPS) without melanin synthesis. At 0.78 g l(-1) N as nitrate, where no melanin synthesis occurred, maximum EPS yields reached 6.92 g l(-1) and then decreased to the final yield of 2.36 g l(-1). Following melanin addition (0.1 g l(-1)), yields reached 7.02 g l(-1) at 48 h and fell to a final yield of 5.21 g l(-1). The EPS produced in high nitrate medium contained both pullulan and (1-->3)-beta-glucan, but only pullulan was produced with melanin-supplementation. With melanin addition a doubling of (1-->3)-beta-glucanase activity was observed in high nitrate medium compared to that without supplementation. On the other hand amylolytic activities disappeared in medium with melanin production or addition. Culture filtrates sustained a higher reducing capacity (RC) when melanin was present. Low RC appeared to reduce (1-->3)-beta-glucanase activity and increase amylolytic activities. Thus, higher RC appears to inhibit production/activity of amylose-degrading enzymes capable of degrading pullulan, and stimulates (1-->3)-beta-glucanase synthesis/activity, leading to a preferential accumulation of pullulan.
Qian, Linbo; Chen, Baoliang
2012-01-01
The effects of interspecific fungal interactions between Trametes versicolor and Phanerochaete chrysosporium on laccase activity and enzymatic oxidation of polycyclic aromatic hydrocarbons (PAHs) were investigated. A deadlock between the two mycelia rather than replacement of one fungus by another was observed on an agar medium. The laccase activity in crude enzyme extracts from interaction zones reached a maximum after a 5-day incubation, which was significantly higher than that from regions of T. versicolor or P. chrysosporium alone. The enhanced induction of laccase activity lasted longer in half nutrition than in normal nutrition. A higher potential to oxidize benzo[a]pyrene by a crude enzyme preparation extracted from the interaction zones was demonstrated. After a 48 hr incubation period, the oxidation of benzo[a]pyrene by crude enzyme extracts from interaction zones reached 26.2%, while only 9.5% of benzo[a]pyrene was oxidized by crude extracts from T. versicolor. The oxidation was promoted by the co-oxidant 2,2'-azinobis-3-ethylbenzthiazoline-6-sulphonate diammonium salt (ABTS). These findings indicate that the application of co-culturing of white-rot fungi in bioremediation is a potential ameliorating technique for the restoration of PAH-contaminated soil.
Hoch, Matthew C; Gaven, Stacey L; Weinhandl, Joshua T
2016-06-01
The Star Excursion Balance Test has identified dynamic postural control deficits in individuals with chronic ankle instability. While kinematic predictors of Star Excursion Balance Test performance have been evaluated in healthy individuals, this has not been thoroughly examined in individuals with chronic ankle instability. Fifteen individuals with chronic ankle instability completed the anterior reach direction of the Star Excursion Balance Test and weight-bearing dorsiflexion assessments. Maximum reach distances on the Star Excursion Balance Test were measured in cm and normalized to leg length. Three-dimensional trunk, hip, knee, and ankle motion of the stance limb were recorded during each anterior reach trial using a motion capture system. Sagittal, frontal, and transverse plane displacement observed from trial initiation to the point of maximum reach was calculated for each joint or segment and averaged for analysis. Pearson product-moment correlations were performed to examine the relationships between kinematic variables, maximal reach, and weight-bearing dorsiflexion. A backward multiple linear regression model was developed with maximal reach as the criterion variable and kinematic variables as predictors. Frontal plane displacement of the trunk, hip, and ankle and sagittal plane knee displacement were entered into the analysis. The final model (p=0.004) included all three frontal plane variables and explained 81% of the variance in maximal reach. Maximal reach distance and several kinematic variables were significantly related to weight-bearing dorsiflexion. Individuals with chronic ankle instability who demonstrated greater lateral trunk displacement toward the stance limb, hip adduction, and ankle eversion achieved greater maximal reach. Copyright © 2016. Published by Elsevier Ltd.
Influence of wheel load shape on vertical stress reaching subgrade through an aggregate layer
DOT National Transportation Integrated Search
2001-03-01
The U.S. Army design procedure to stabilize low-bearing capacity soil with geotextiles is based on the assumption that the applied surface load (the wheel load) is in the shape of a circle. The maximum vertical stress that reaches the subgrade throug...
Pore structure modified diatomite-supported PEG composites for thermal energy storage
NASA Astrophysics Data System (ADS)
Qian, Tingting; Li, Jinhong; Deng, Yong
2016-09-01
A series of novel composite phase change materials (PCMs) were tailored by blending PEG and five kinds of diatomite via a vacuum impregnation method. To enlarge its pore size and specific surface area, different modification approaches including calcination, acid treatment, alkali leaching and nano-silica decoration on the microstructure of diatomite were outlined. Among them, 8 min of 5 wt% NaOH dissolution at 70 °C has been proven to be the most effective and facile. While PEG melted during phase transformation, the maximum load of PEG could reach 70 wt.%, which was 46% higher than that of the raw diatomite. The apparent activation energy of PEG in the composite was 1031.85 kJ·mol-1, which was twice higher than that of the pristine PEG. Moreover, using the nano-silica decorated diatomite as carrier, the maximum PEG load was 66 wt%. The composite PCM was stable in terms of thermal and chemical manners even after 200 cycles of melting and freezing. All results indicated that the obtained composite PCMs were promising candidate materials for building applications due to its large latent heat, suitable phase change temperature, excellent chemical compatibility, improved supercooling extent, high thermal stability and long-term reliability.
Pore structure modified diatomite-supported PEG composites for thermal energy storage
Qian, Tingting; Li, Jinhong; Deng, Yong
2016-01-01
A series of novel composite phase change materials (PCMs) were tailored by blending PEG and five kinds of diatomite via a vacuum impregnation method. To enlarge its pore size and specific surface area, different modification approaches including calcination, acid treatment, alkali leaching and nano-silica decoration on the microstructure of diatomite were outlined. Among them, 8 min of 5 wt% NaOH dissolution at 70 °C has been proven to be the most effective and facile. While PEG melted during phase transformation, the maximum load of PEG could reach 70 wt.%, which was 46% higher than that of the raw diatomite. The apparent activation energy of PEG in the composite was 1031.85 kJ·mol−1, which was twice higher than that of the pristine PEG. Moreover, using the nano-silica decorated diatomite as carrier, the maximum PEG load was 66 wt%. The composite PCM was stable in terms of thermal and chemical manners even after 200 cycles of melting and freezing. All results indicated that the obtained composite PCMs were promising candidate materials for building applications due to its large latent heat, suitable phase change temperature, excellent chemical compatibility, improved supercooling extent, high thermal stability and long-term reliability. PMID:27580677
Pore structure modified diatomite-supported PEG composites for thermal energy storage.
Qian, Tingting; Li, Jinhong; Deng, Yong
2016-09-01
A series of novel composite phase change materials (PCMs) were tailored by blending PEG and five kinds of diatomite via a vacuum impregnation method. To enlarge its pore size and specific surface area, different modification approaches including calcination, acid treatment, alkali leaching and nano-silica decoration on the microstructure of diatomite were outlined. Among them, 8 min of 5 wt% NaOH dissolution at 70 °C has been proven to be the most effective and facile. While PEG melted during phase transformation, the maximum load of PEG could reach 70 wt.%, which was 46% higher than that of the raw diatomite. The apparent activation energy of PEG in the composite was 1031.85 kJ·mol(-1), which was twice higher than that of the pristine PEG. Moreover, using the nano-silica decorated diatomite as carrier, the maximum PEG load was 66 wt%. The composite PCM was stable in terms of thermal and chemical manners even after 200 cycles of melting and freezing. All results indicated that the obtained composite PCMs were promising candidate materials for building applications due to its large latent heat, suitable phase change temperature, excellent chemical compatibility, improved supercooling extent, high thermal stability and long-term reliability.
An ion source for radiofrequency-pulsed glow discharge time-of-flight mass spectrometry
NASA Astrophysics Data System (ADS)
González Gago, C.; Lobo, L.; Pisonero, J.; Bordel, N.; Pereiro, R.; Sanz-Medel, A.
2012-10-01
A Grimm-type glow discharge (GD) has been designed and constructed as an ion source for pulsed radiofrequency GD spectrometry when coupled to an orthogonal time of flight mass spectrometer. Pulse shapes of argon species and analytes were studied as a function of the discharge conditions using a new in-house ion source (UNIOVI GD) and results have been compared with a previous design (PROTOTYPE GD). Different behavior and shapes of the pulse profiles have been observed for the two sources evaluated, particularly for the plasma gas ionic species detected. In the more analytically relevant region (afterglow), signals for 40Ar+ with this new design were negligible, while maximum intensity was reached earlier in time for 41(ArH)+ than when using the PROTOTYPE GD. Moreover, while maximum 40Ar+ signals measured along the pulse period were similar in both sources, 41(ArH)+ and 80(Ar2)+ signals tend to be noticeable higher using the PROTOTYPE chamber. The UNIOVI GD design was shown to be adequate for sensitive direct analysis of solid samples, offering linear calibration graphs and good crater shapes. Limits of detection (LODs) are in the same order of magnitude for both sources, although the UNIOVI source provides slightly better LODs for those analytes with masses slightly higher than 41(ArH)+.
Pyrolysis polygeneration of poplar wood: Effect of heating rate and pyrolysis temperature.
Chen, Dengyu; Li, Yanjun; Cen, Kehui; Luo, Min; Li, Hongyan; Lu, Bin
2016-10-01
The pyrolysis of poplar wood were comprehensively investigated at different pyrolysis temperatures (400, 450, 500, 550, and 600°C) and at different heating rates (10, 30, and 50°C/min). The results showed that BET surface area of biochar, the HHV of non-condensable gas and bio-oil reached the maximum values of 411.06m(2)/g, 14.56MJ/m(3), and 14.39MJ/kg, under the condition of 600°C and 30°C/min, 600°C and 50°C/min, and 550°C and 50°C/min, respectively. It was conducive to obtain high mass and energy yield of bio-oil at 500°C and higher heating rate, while lower pyrolysis temperature and heating rate contributed towards obtaining both higher mass yield and energy yield of biochar. However, higher pyrolysis temperature and heating rate contributed to obtain both higher mass yield and energy yield of the non-condensable gas. In general, compared to the heating rate, the pyrolysis temperature had more effect on the product properties. Copyright © 2016 Elsevier Ltd. All rights reserved.
Panno, Angelo; Carrus, Giuseppe; Lafortezza, Raffaele; Mariani, Luigi; Sanesi, Giovanni
2017-11-01
Air temperatures are increasing because of global climate change. A warming phenomenon strongly related to global climate change is the urban heat island. It has been shown that the hotter temperatures occurring in cities during the summer negatively affect human wellbeing, but little is known about the potential mechanisms underlying the relationships between hotter temperatures, cognitive psychological resources and wellbeing. The aim of the present research is to understand whether, and how, spending time in urban green spaces, which can be considered as a specific kind of Nature-Based Solution (NBS), helps the recovery of cognitive resources and wellbeing. The main hypothesis is that contact with urban green is related to wellbeing through the depletion of cognitive resources (i.e., ego depletion). Moreover, we expected that individuals showing higher scores of ego depletion also report a higher estimate of the maximum temperature reached during the summer. The results of a survey (N = 115) conducted among visitors to Parco Nord Milano, a large urban park located in Milan (Italy), point out that people visiting the park during the summer show a higher level of wellbeing as well as a lower level of ego depletion. A mediation analysis shows that visiting urban green spaces is associated with greater wellbeing through less ego depletion. Our results also point out that, as expected, people showing a higher level of ego depletion tend to overestimate the maximum air temperature. Implications for future studies and applied interventions regarding the role of NBS to promote human wellbeing are discussed. Copyright © 2017 Elsevier Inc. All rights reserved.
Prospecting for Marine Bacteria for Polyhydroxyalkanoate Production on Low-Cost Substrates
Takahashi, Rodrigo Yoji Uwamori; Castilho, Nathalia Aparecida Santos; da Silva, Marcus Adonai Castro; Miotto, Maria Cecilia; Lima, André Oliveira de Souza
2017-01-01
Polyhydroxyalkanoates (PHAs) are a class of biopolymers with numerous applications, but the high cost of production has prevented their use. To reduce this cost, there is a prospect for strains with a high PHA production and the ability to grow in low-cost by-products. In this context, the objective of this work was to evaluate marine bacteria capable of producing PHA. Using Nile red, 30 organisms among 155 were identified as PHA producers in the medium containing starch, and 27, 33, 22 and 10 strains were found to be positive in media supplemented with carboxymethyl cellulose, glycerol, glucose and Tween 80, respectively. Among the organisms studied, two isolates, LAMA 677 and LAMA 685, showed strong potential to produce PHA with the use of glycerol as the carbon source, and were selected for further studies. In the experiment used to characterize the growth kinetics, LAMA 677 presented a higher maximum specific growth rate (µmax = 0.087 h−1) than LAMA 685 (µmax = 0.049 h−1). LAMA 677 also reached a D-3-hydroxybutyrate (P(3HB)) content of 78.63% (dry biomass), which was 3.5 times higher than that of LAMA 685. In the assay of the production of P(3HB) from low-cost substrates (seawater and biodiesel waste glycerol), LAMA 677 reached a polymer content of 31.7%, while LAMA 685 reached 53.6%. Therefore, it is possible to conclude that the selected marine strains have the potential to produce PHA, and seawater and waste glycerol may be alternative substrates for the production of this polymer. PMID:28952539
Synthesis, optimization, and characterization of molecularly imprinted nanoparticles
NASA Astrophysics Data System (ADS)
Rostamizadeh, Kobra; Abdollahi, Hamid; Parsajoo, Cobra
2013-04-01
Nanoparticles of molecularly imprinted polymers (MIPs) were prepared by precipitation polymerization method. Glucose was used as a template molecule. The impact of different process parameters on the preparation of nanoparticles was investigated in order to reach the maximum binding capacity of MIPs. Experimental data based on uniform design were analyzed using artificial neural network to find the optimal condition. The results showed that the binding ability of nanoparticles of MIPs prepared under optimum condition was much higher than that of the corresponding non-imprinted nanoparticles (NIPs). The findings also demonstrated high glucose selectivity of imprinted nanoparticles. The results exhibited that the particle size for MIP nanoparticles was about 557.6 nm, and the Brunauer-Emmett-Teller analysis also confirmed that the particle pores were mesopores and macropores around 40 nm and possessed higher volume, surface area, and uniform size compared to the corresponding NIPs.
Solar thermal power & gas turbine hybrid design with molten salt storage tank
NASA Astrophysics Data System (ADS)
Martín, Fernando; Wiesenberg, Ralf; Santana, Domingo
2017-06-01
Taking into consideration the need to decelerate the global climatic change, power generation has to shift from burning fossil fuel to renewable energy source in short medium period of time. In this work, we are presenting a new model of a solar-gas natural hybrid power cycle with the main aim of decoupling the solar generation system from the gas turbine system. The objective is to have high solar power contribution compared to conventional ISCC plants [2], producing firm and dispatchable electricity at the same time. The decoupling is motivated by the low solar contribution reached by the ISCC, which is technically limited to maximum of 15%, [4]. In our case, we have implemented a solar tower with molten salts as working fluid. Central receiver systems get higher performance than others systems, like parabolic trough technology [1], due to the higher temperature achieved in the heat transferred fluid HTF, close to 560°C.
Precursor–product relationship between intrahepatic albumin and plasma albumin
LeBouton, A. V.
1968-01-01
Rats were injected with [3H]leucine, and at various times thereafter labelled albumin was isolated by electrophoresis from their livers and blood plasma. The specific radioactivity of each protein was determined by spectrophotometry and liquid-scintillation spectrometry. Intrahepatic albumin was shown to be identical with plasma albumin by its electrophoretic mobility and antigenicity. It was found that intrahepatic albumin was the direct precursor of plasma albumin. Comparison of their specific radioactivities showed that intrahepatic albumin attained a higher specific radioactivity before plasma albumin. When plasma albumin reached its maximum specific radioactivity, that of intrahepatic albumin had decreased to a similar value. Thereafter, the specific radioactivity of intrahepatic albumin remained lower than that of plasma albumin. PMID:4966084
Kinetic limitations on the diffusional control theory of the ablation rate of carbon.
NASA Technical Reports Server (NTRS)
Maahs, H. G.
1971-01-01
It is shown that the theoretical maximum oxidation rate is limited in many cases even at temperatures much higher than 1650 deg K, not by oxygen transport, but by the kinetics of the carbon-oxygen reaction itself. Mass-loss rates have been calculated at air pressures of 0.01 atm, 1 atm, and 100 atm. It is found that at high temperatures the rate of the oxidation reaction is much slower than has generally been assumed on the basis of a simple linear extrapolation of Scala's 'fast' and 'slow' rate expressions. Accordingly it cannot be assumed that a transport limitation inevitably must be reached at high temperatures.
Ma, Yunfeng; Xiang, Fu; Xiang, Jun; Yu, Longjiang
2012-01-01
Selenium is an essential nutrient with diverse physiological functions, and soluble organic selenium (SOS) sources have a higher bioavailability than inorganic selenium sources. Based on the response surface methodology and central composite design, this study presents the optimal medium components for SOS accumulation in batch cultures of Flammulina velutipes, i.e. 30 g/L glucose, 11.2 mg/L sodium selenite, and 1.85 g/L NH4NO3. Furthermore, logistic function model feeding was found to be the optimal feeding strategy for SOS accumulation during Flammulina velutipes mycelia fermentation, where the maximum SOS accumulation reached (4.63 +/- 0.24) mg/L, which is consistent with the predicted value.
Ben-Harari, R. R.; Youdim, M. B.
1981-01-01
1. Uptake of 5-hydroxytryptamine (5-HT) and beta-phenylethylamine (PEA) was studied in perfused lung from male rats between 10 and 70 days old. 2. Monoamine oxidase (MAO) activity towards 5-HT, PEA and dopamine was studied in homogenate preparations of lung from rats aged between 5 and 80 days. 3. Uptake of 5-HT (10 microM) decreased throughout the age range studied but uptake of PEA (50 microM) increased for the first 30 days and beyond this age it decreased. Metabolites formed for both amines reflected the changes in uptake. 4. MAO activity deaminating 5-HT is well developed by day 10 and reaches its maximum by day 40. For dopamine and PEA, MAO activity remained low until day 20, and the developed rapidly, reaching a maximum by day 40 for dopamine; activity towards PEA did not reach a maximum by day 80. 5. These results show that uptake and MAO activity changes with age and thus the lung responds like other tissues. 6. These results also demonstrate the independent development of uptake and MAO activity towards 5-HT, PEA and dopamine. PMID:7284689
Impact of Saccharomyces cerevisiae strains on traditional sparkling wines production.
Di Gianvito, Paola; Perpetuini, Giorgia; Tittarelli, Fabrizia; Schirone, Maria; Arfelli, Giuseppe; Piva, Andrea; Patrignani, Francesca; Lanciotti, Rosalba; Olivastri, Lino; Suzzi, Giovanna; Tofalo, Rosanna
2018-07-01
Sparkling wine fermentation is a challenge for yeasts due to the hostile conditions. A phenotype sought in starters is flocculation, because it reduces riddling time. For this reason, six flocculent Saccharomyces cerevisiae wine strains with different flocculation degree and autolytic activity and two commercial strains were tested for traditional sparkling wine production in a winery. Yeast viability, free aminoacids and high molecular weight nitrogen release and physico-chemical composition of sparkling wines were evaluated. Moreover, strains were tested for their aromatic potential. Obtained data revealed that flocculent yeasts presented oenological performances (in terms of fermentation rate, maximum pressure reached, free aminoacids - AAN and high molecular weight nitrogen - HMWN release) similar to the commercial strains. All considered strains were able to complete fermentation and viable cells of all strains were detected in all sparkling wines produced even after 6 months. F6789 and F10471 strains showed slow fermentation kinetics reaching the maximum of pressure at 180 days. Regarding nitrogen compounds release, FI strain was characterized by the highest amount of AAN and HMWN released, followed by F6789. Strains showed a considerable diversification in terms of number and amount of aroma molecules produced and sparkling wines obtained with autochthonous flocculent strains presented a higher amount of alcohols and esters already after 3 months. Further studies are necessary to select starter strains to improve traditional sparkling wines production. Copyright © 2018 Elsevier Ltd. All rights reserved.
Thermodynamics Analysis of Refinery Sludge Gasification in Adiabatic Updraft Gasifier
Ahmed, Reem; Sinnathambi, Chandra M.; Eldmerdash, Usama; Subbarao, Duvvuri
2014-01-01
Limited information is available about the thermodynamic evaluation for biomass gasification process using updraft gasifier. Therefore, to minimize errors, the gasification of dry refinery sludge (DRS) is carried out in adiabatic system at atmospheric pressure under ambient air conditions. The objectives of this paper are to investigate the physical and chemical energy and exergy of product gas at different equivalent ratios (ER). It will also be used to determine whether the cold gas, exergy, and energy efficiencies of gases may be maximized by using secondary air injected to gasification zone under various ratios (0, 0.5, 1, and 1.5) at optimum ER of 0.195. From the results obtained, it is indicated that the chemical energy and exergy of producer gas are magnified by 5 and 10 times higher than their corresponding physical values, respectively. The cold gas, energy, and exergy efficiencies of DRS gasification are in the ranges of 22.9–55.5%, 43.7–72.4%, and 42.5–50.4%, respectively. Initially, all 3 efficiencies increase until they reach a maximum at the optimum ER of 0.195; thereafter, they decline with further increase in ER values. The injection of secondary air to gasification zone is also found to increase the cold gas, energy, and exergy efficiencies. A ratio of secondary air to primary air of 0.5 is found to be the optimum ratio for all 3 efficiencies to reach the maximum values. PMID:24672368
Petrillo, Antonella; Fusco, Roberta; Petrillo, Mario; Granata, Vincenza; Delrio, Paolo; Bianco, Francesco; Pecori, Biagio; Botti, Gerardo; Tatangelo, Fabiana; Caracò, Corradina; Aloj, Luigi; Avallone, Antonio; Lastoria, Secondo
2017-01-01
Purpose To investigate dynamic contrast enhanced-MRI (DCE-MRI) in the preoperative chemo-radiotherapy (CRT) assessment for locally advanced rectal cancer (LARC) compared to18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT). Methods 75 consecutive patients with LARC were enrolled in a prospective study. DCE-MRI analysis was performed measuring SIS: linear combination of percentage change (Δ) of maximum signal difference (MSD) and wash-out slope (WOS). 18F-FDG PET/CT analysis was performed using SUV maximum (SUVmax). Tumor regression grade (TRG) were estimated after surgery. Non-parametric tests, receiver operating characteristic were evaluated. Results 55 patients (TRG1-2) were classified as responders while 20 subjects as non responders. ΔSIS reached sensitivity of 93%, specificity of 80% and accuracy of 89% (cut-off 6%) to differentiate responders by non responders, sensitivity of 93%, specificity of 69% and accuracy of 79% (cut-off 30%) to identify pathological complete response (pCR). Therapy assessment via ΔSUVmax reached sensitivity of 67%, specificity of 75% and accuracy of 70% (cut-off 60%) to differentiate responders by non responders and sensitivity of 80%, specificity of 31% and accuracy of 51% (cut-off 44%) to identify pCR. Conclusions CRT response assessment by DCE-MRI analysis shows a higher predictive ability than 18F-FDG PET/CT in LARC patients allowing to better discriminate significant and pCR. PMID:28042958
Wei, Xuetuan; Zhou, Yinhua; Chen, Jingbang; Cai, Dongbo; Wang, Dan; Qi, Gaofu; Chen, Shouwen
2015-02-01
Nattokinase (NK) possesses the potential for prevention and treatment of thrombus-related diseases. In this study, high-level expression of nattokinase was achieved in Bacillus licheniformis WX-02 via host strain construction and signal peptides optimization. First, ten genes (mpr, vpr, aprX, epr, bpr, wprA, aprE, bprA, hag, amyl) encoding for eight extracellular proteases, a flagellin and an amylase were deleted to obtain B. licheniformis BL10, which showed no extracellular proteases activity in gelatin zymography. Second, the gene fragments of P43 promoter, Svpr, nattokinase and TamyL were combined into pHY300PLK to form the expression vector pP43SNT. In BL10 (pP43SNT), the fermentation activity and product activity per unit of biomass of nattokinase reached 14.33 FU/mL and 2,187.71 FU/g respectively, which increased by 39 and 156 % compared to WX-02 (pP43SNT). Last, Svpr was replaced with SsacC and SbprA, and the maximum fermentation activity (33.83 FU/mL) was achieved using SsacC, which was 229 % higher than that of WX-02 (pP43SNT). The maximum NK fermentation activity in this study reaches the commercial production level of solid state fermentation, and this study provides a promising engineered strain for industrial production of nattokinase, as well as a potential platform host for expression of other target proteins.
Li, Zhen; Bai, Tongshuo; Dai, Letian; Wang, Fuwei; Tao, Jinjin; Meng, Shiting; Hu, Yunxiao; Wang, Shimei; Hu, Shuijin
2016-01-01
Phosphate solubilizing fungi (PSF) have huge potentials in enhancing release of phosphorus from fertilizer. Two PSF (NJDL-03 and NJDL-12) were isolated and identified as Penicillium oxalicum and Aspergillus niger respectively in this study. The quantification and identification of organic acids were performed by HPLC. Total concentrations of organic acids secreted by NJDL-03 and NJDL-12 are ~4000 and ~10,000 mg/L with pH values of 3.6 and 2.4 respectively after five-days culture. Oxalic acid dominates acidity in the medium due to its high concentration and high acidity constant. The two fungi were also cultured for five days with the initial pH values of the medium varied from 6.5 to 1.5. The biomass reached the maximum when the initial pH values are 4.5 for NJDL-03 and 2.5 for NJDL-12. The organic acids for NJDL-12 reach the maximum at the initial pH = 5.5. However, the acids by NJDL-03 continue to decrease and proliferation of the fungus terminates at pH = 2.5. The citric acid production increases significantly for NJDL-12 at acidic environment, whereas formic and oxalic acids decrease sharply for both two fungi. This study shows that NJDL-12 has higher ability in acid production and has stronger adaptability to acidic environment than NJDL-03. PMID:27126606
Petrillo, Antonella; Fusco, Roberta; Petrillo, Mario; Granata, Vincenza; Delrio, Paolo; Bianco, Francesco; Pecori, Biagio; Botti, Gerardo; Tatangelo, Fabiana; Caracò, Corradina; Aloj, Luigi; Avallone, Antonio; Lastoria, Secondo
2017-01-31
To investigate dynamic contrast enhanced-MRI (DCE-MRI) in the preoperative chemo-radiotherapy (CRT) assessment for locally advanced rectal cancer (LARC) compared to18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT). 75 consecutive patients with LARC were enrolled in a prospective study. DCE-MRI analysis was performed measuring SIS: linear combination of percentage change (Δ) of maximum signal difference (MSD) and wash-out slope (WOS). 18F-FDG PET/CT analysis was performed using SUV maximum (SUVmax). Tumor regression grade (TRG) were estimated after surgery. Non-parametric tests, receiver operating characteristic were evaluated. 55 patients (TRG1-2) were classified as responders while 20 subjects as non responders. ΔSIS reached sensitivity of 93%, specificity of 80% and accuracy of 89% (cut-off 6%) to differentiate responders by non responders, sensitivity of 93%, specificity of 69% and accuracy of 79% (cut-off 30%) to identify pathological complete response (pCR). Therapy assessment via ΔSUVmax reached sensitivity of 67%, specificity of 75% and accuracy of 70% (cut-off 60%) to differentiate responders by non responders and sensitivity of 80%, specificity of 31% and accuracy of 51% (cut-off 44%) to identify pCR. CRT response assessment by DCE-MRI analysis shows a higher predictive ability than 18F-FDG PET/CT in LARC patients allowing to better discriminate significant and pCR.
Sharma, Parbodh C.; Singh, Dhananjay; Sehgal, Deepmala; Singh, Gurbachan; Hash, C.T.; Yadav, Rattan S.
2014-01-01
Earlier, we established that a major drought tolerance QTL on linkage group 2 of pearl millet is also associated with reduced salt uptake and enhanced growth under salt stress. Present study was undertaken to re-assess the performance of drought tolerant (PRLT 2/89-33) and drought sensitive (H 77/833-2) parents along with two QTL-NILs (ICMR 01029 and ICMR 01040), under salinity stress specifically imposed during post-flowering growth stages when plants had developed their ion sinks in full. Time course changes in ionic accumulation and their compartmentalization in different plant parts was studied, specifically to monitor and capture changes conferred by the two alleles at this QTL, at small intervals. Amongst different plant parts, higher accumulation of toxic ion Na+ was recorded in roots. Further, the Na+ concentration in roots of the testcross hybrid of the drought-sensitive parent (H 77/833-2) reached its maximum at ECiw 15 dS m−1 within 24 h after salinity imposition, whereas it continued to increase with time in the testcross hybrids of the drought tolerant parent PRLT 2/89-33 as well as those of its QTL-NILs (ICMR 01029 and ICMR 01004) and reached at its maximum at 120 h stage. Comparison of differential distribution of toxic ions in individual leaves revealed that Na+ ions were not uniformly distributed in the leaves of the drought-tolerant parent and drought-tolerant QTL-NILs; but accumulated preferentially in the older leaves, whereas the hybrid of the drought-sensitive parent showed significantly higher Na+ concentration in all main stem leaves irrespective of their age. Dynamics of chlorophyll and proline concentration variation studied under salt stress at late flowering stages revealed a greater reduction, almost twice, in both leaf chlorophyll and proline concentrations in younger leaves in the hybrids of the sensitive parent as compared to the tolerant parent and QTL NILs. Imposition of salinity stress even at flowering stage affected the yield performance in pearl millet, wherein higher yield was recorded in drought tolerant parent and the two QTL-NILs compared to drought sensitive parent. PMID:24895469
Suinyuy, Terence N.; Donaldson, John S.; Johnson, Steven D.
2013-01-01
Background and Aims Ontogenetic patterns of odour emissions and heating associated with plant reproductive structures may have profound effects on insect behaviour, and consequently on pollination. In some cycads, notably Macrozamia, temporal changes in emission of specific odour compounds and temperature have been interpreted as a ‘push–pull’ interaction in which pollinators are either attracted or repelled according to the concentration of the emitted volatiles. To establish which mechanisms occur in the large Encephalartos cycad clade, the temporal patterns of volatile emissions, heating and pollinator activity of cones of Encephalartos villosus in the Eastern Cape (EC) and KwaZulu Natal (KZN) of South Africa were investigated. Methods and Key Results Gas chromatography–mass spectrometry (GC-MS) analyses of Encephalartos villosus cone volatiles showed that emissions, dominated by eucalyptol and 2-isopropyl-3-methoxypyrazine in EC populations and (3E)-1,3-octadiene and (3E,5Z)-1,3,5-octatriene in the KZN populations, varied across developmental stages but did not vary significantly on a daily cycle. Heating in male cones was higher at dehiscence than during pre- and post-dehiscence, and reached a maximum at about 1830 h when temperatures were between 7·0 and 12·0 °C above ambient. Daily heating of female cones was less pronounced and reached a maximum at about 1345 h when it was on average between 0·9 and 3·0 °C above ambient. Insect abundance on male cones was higher at dehiscence than at the other stages and significantly higher in the afternoon than in the morning and evening. Conclusions There are pronounced developmental changes in volatile emissions and heating in E. villosus cones, as well as strong daily changes in thermogenesis. Daily patterns of volatile emissions and pollinator abundance in E. villosus are different from those observed in some Macrozamia cycads and not consistent with the push–pull pattern as periods of peak odour emission do not coincide with mass exodus of insects from male cones. PMID:23887092
NASA Astrophysics Data System (ADS)
Latcharote, Panon; Suppasri, Anawat; Imamura, Fumihiko; Aytore, Betul; Yalciner, Ahmet Cevdet
2016-12-01
This study evaluates tsunami hazards in the Marmara Sea from possible worst-case tsunami scenarios that are from submarine earthquakes and landslides. In terms of fault-generated tsunamis, seismic ruptures can propagate along the North Anatolian Fault (NAF), which has produced historical tsunamis in the Marmara Sea. Based on the past studies, which consider fault-generated tsunamis and landslide-generated tsunamis individually, future scenarios are expected to generate tsunamis, and submarine landslides could be triggered by seismic motion. In addition to these past studies, numerical modeling has been applied to tsunami generation and propagation from combined earthquake and landslide sources. In this study, tsunami hazards are evaluated from both individual and combined cases of submarine earthquakes and landslides through numerical tsunami simulations with a grid size of 90 m for bathymetry and topography data for the entire Marmara Sea region and validated with historical observations from the 1509 and 1894 earthquakes. This study implements TUNAMI model with a two-layer model to conduct numerical tsunami simulations, and the numerical results show that the maximum tsunami height could reach 4.0 m along Istanbul shores for a full submarine rupture of the NAF, with a fault slip of 5.0 m in the eastern and western basins of the Marmara Sea. The maximum tsunami height for landslide-generated tsunamis from small, medium, and large of initial landslide volumes (0.15, 0.6, and 1.5 km3, respectively) could reach 3.5, 6.0, and 8.0 m, respectively, along Istanbul shores. Possible tsunamis from submarine landslides could be significantly higher than those from earthquakes, depending on the landslide volume significantly. These combined earthquake and landslide sources only result in higher tsunami amplitudes for small volumes significantly because of amplification within the same tsunami amplitude scale (3.0-4.0 m). Waveforms from all the coasts around the Marmara Sea indicate that other residential areas might have had a high risk of tsunami hazards from submarine landslides, which can generate higher tsunami amplitudes and shorter arrival times, compared to Istanbul.
Cerri, M O; Badino, A C
2012-08-01
In biochemical processes involving filamentous microorganisms, the high shear rate may damage suspended cells leading to viability loss and cell disruption. In this work, the influence of the shear conditions in clavulanic acid (CA) production by Streptomyces clavuligerus was evaluated in a 4-dm(3) conventional stirred tank (STB) and in 6-dm(3) concentric-tube airlift (ALB) bioreactors. Batch cultivations were performed in a STB at 600 and 800 rpm and 0.5 vvm (cultivations B1 and B2) and in ALB at 3.0 and 4.1 vvm (cultivations A1 and A2) to define two initial oxygen transfer conditions in both bioreactors. The average shear rate ([Formula: see text]) of the cultivations was estimated using correlations of recent literature based on experimental data of rheological properties of the broth (consistency index, K, and flow index, n) and operating conditions, impeller speed (N) for STB and superficial gas velocity in the riser (UGR) for ALB. In the same oxygen transfer condition, the [Formula: see text] values for ALB were higher than those obtained in STB. The maximum [Formula: see text] presented a strong correlation with a maximum consistency index (K (max)) of the broth. Close values of maximum CA production were obtained in cultivations A1 and A2 (454 and 442 mg L(-1)) with similar maximum [Formula: see text] values of 4,247 and 4,225 s(-1). In cultivations B1 and B2, the maximum CA production of 269 and 402 mg L(-1) were reached with a maximum [Formula: see text] of 904 and 1,786 s(-1). The results show that high values of average shear rate increase the CA production regardless of the oxygen transfer condition and bioreactor model.
Strong ground motion from the November 12, 2017, M 7.3 Kermanshah earthquake in western Iran
NASA Astrophysics Data System (ADS)
Babaie Mahani, Alireza; Kazemian, Javad
2018-05-01
In this paper, we analyzed the strong ground motion from the November 12, 2017, Kermanshah earthquake in western Iran with moment magnitude (M) of 7.3. Nonlinear and linear amplification of ground motion amplitudes were observed at stations with soft soil condition at hypocentral distances below and above 100 km, respectively. Observation of large ground motion amplitudes dominated with long-period pulses on the strike-normal component of the velocity time series suggests a right-lateral component of movement and propagation of rupture towards southeast. Comparison of the horizontal peak ground acceleration (PGA) from the M 7.3 earthquake with global PGA values showed a similar decay in ground motion amplitudes, although it seems that PGA from the M 7.3 Kermanshah earthquake is higher than global values for NEHRP site class B. We also found that the bracketed duration (D b) was higher in the velocity domain than in the acceleration domain for the same modified Mercalli intensity (MMI) threshold. For example, D b reached 30 s at the maximum PGA while it was 50 s at the maximum peak ground velocity above the threshold of MMI = 5. Although the standard design spectrum from Iranian Code of Practice for Seismic Resistant Design of Buildings (standard No. 2800) seems to include appropriate values for the design of structures with fundamental period of 1 s and higher, it is underestimated for near-field ground motions at lower periods.
de Abreu, Daniela Cristina Carvalho; Takara, Kelly; Metring, Nathália Lopes; Reis, Júlia Guimarães; Cliquet, Alberto
2012-09-01
We aimed to evaluate the influence of different types of wheelchair seats on paraplegic individuals' postural control using a maximum anterior reaching test. Balance evaluations during 50, 75, and 90% of each individual's maximum reach in the forward direction using two different cushions on seat (one foam and one gel) and a no-cushion condition were carried out on 11 individuals with a spinal cord injury (SCI) and six individuals without SCI. Trunk anterior displacement and the time spent to perform the test were assessed. No differences were found for the three types of seats in terms of trunk anterior displacement and the time spent to perform the test when intragroup comparisons were made in both groups (P>0.05). The intergroup comparison showed that body displacement was less prominent and the time spent to perform the test was more prolonged for individuals with SCI (P<0.05), which suggests a postural control deficit. The seat type did not affect the ability of the postural control system to maintain balance during the forward-reaching task.
Bombesin and G-17 dose responses in duodenal ulcer and controls.
Hirschowitz, B I; Tim, L O; Helman, C A; Molina, E
1985-11-01
Gastric acid and pepsin secretion and serum gastrin concentrations were measured in nine patients with uncomplicated duodenal ulcer (DU) and 10 normal controls in the fasting state and in response to graded doses of bombesin, a tetradecapeptide gastrin releaser, and, for reference, synthetic gastrin G-17. Serum gastrin with bombesin stimulation was significantly greater in duodenal ulcer (maximum 467 pg/ml) than in controls (153 pg/ml), while in seven of the DU group tested gastrin levels after a meal were not different from that seen in five of the normal controls. Gastric acid concentrations and outputs were greater in duodenal ulcer with both stimuli. Secretory responses were then related to serum gastrin levels; despite increasing gastrin levels with bombesin stimulation, peak outputs achieved with bombesin were only 50% of G-17 maximum in normals and up to 90% of maximum in duodenal ulcer. Up to the point of peak response to bombesin, acid and pepsin outputs were the same with exogenous and endogenous gastrin, ie, bombesin acted only via G-17. Furthermore, in direct comparison of duodenal ulcer and normals with G-17 infusion, acid and pepsin outputs related to serum gastrin were congruent up to 75% of duodenal ulcer maximum, at which point normals reached their maximum level. These data have shown that duodenal ulcer patients are not more sensitive to either exogenous or endogenous gastrin; we have also shown regulatory defects in duodenal ulcer patients not previously described: an exaggerated release of gastrin with bombesin stimulation, and a defective inhibition of acid and pepsin secretion with higher doses of bombesin.
Molina, L; Elosua, R; Marrugat, J; Pons, S
1999-10-15
The relation between maximum systolic blood pressure (BP) during exercise and left ventricular (LV) mass is controversial. Physical activity also induces LV mass increase. The objective was to assess the relation between BP response to exercise and LV mass in normotensive men, taking into account physical activity practice. A cross-sectional study was performed. Three hundred eighteen healthy normotensive men, aged between 20 and 60 years, participated in this study. The Minnesota questionnaire was used to assess physical activity practice. An echocardiogram and a maximum exercise test were performed. LV mass was calculated and indexed to body surface area. LV hypertrophy was defined as a ventricular mass index > or =134 g/m2. BP was measured at the moment of maximum effort. Hypertensive response was considered when BP was > or =210 mm Hg. In the multiple linear regression model, maximum systolic BP was associated with LV mass index and correlation coefficient was 0.27 (SE 0.07). Physical activity practice and age were also associated with LV mass. An association between hypertensive response to exercise and LV hypertrophy was observed (odds ratio 3.16). Thus, BP response to exercise is associated with LV mass and men with systolic BP response > or =210 mm Hg present a 3-times higher risk of LV hypertrophy than those not reaching this limit. Physical activity practice is related to LV mass, but not to LV hypertrophy.
NASA Technical Reports Server (NTRS)
Madzsar, George C. (Inventor)
1993-01-01
The elemental composition of a material exposed to hot gases and subjected to wear is determined. Atoms of an elemental species not appearing in this material are implanted in a surface at a depth based on the maximum allowable wear. The exhaust gases are spectroscopically monitored to determine the exposure of these atoms when the maximum allowable wear is reached.
Modulation of hand aperture during reaching in persons with incomplete cervical spinal cord injury.
Stahl, Victoria A; Hayes, Heather B; Buetefisch, Cathrin M; Wolf, Steven L; Trumbower, Randy D
2015-03-01
The intact neuromotor system prepares for object grasp by first opening the hand to an aperture that is scaled according to object size and then closing the hand around the object. After cervical spinal cord injury (SCI), hand function is significantly impaired, but the degree to which object-specific hand aperture scaling is affected remains unknown. Here, we hypothesized that persons with incomplete cervical SCI have a reduced maximum hand opening capacity but exhibit novel neuromuscular coordination strategies that permit object-specific hand aperture scaling during reaching. To test this hypothesis, we measured hand kinematics and surface electromyography from seven muscles of the hand and wrist during attempts at maximum hand opening as well as reaching for four balls of different diameters. Our results showed that persons with SCI exhibited significantly reduced maximum hand aperture compared to able-bodied (AB) controls. However, persons with SCI preserved the ability to scale peak hand aperture with ball size during reaching. Persons with SCI also used distinct muscle coordination patterns that included increased co-activity of flexors and extensors at the wrist and hand compared to AB controls. These results suggest that motor planning for aperture modulation is preserved even though execution is limited by constraints on hand opening capacity and altered muscle co-activity. Thus, persons with incomplete cervical SCI may benefit from rehabilitation aimed at increasing hand opening capacity and reducing flexor-extensor co-activity at the wrist and hand.
Modulation of hand aperture during reaching in persons with incomplete cervical spinal cord injury
Stahl, Victoria; Hayes, Heather B; Buetefisch, Cathrin; Wolf, Steven L; Trumbower, Randy D
2014-01-01
The intact neuromotor system prepares for object grasp by first opening the hand to an aperture that is scaled according to object size and then closing the hand around the object. After cervical spinal cord injury (SCI), hand function is significantly impaired, but the degree to which object-specific hand aperture scaling is affected remains unknown. Here we hypothesized that persons with incomplete cervical SCI have a reduced maximum hand opening capacity but exhibit novel neuromuscular coordination strategies that permit object-specific hand aperture scaling during reaching. To test this hypothesis, we measured hand kinematics and surface electromyography (EMG) from seven muscles of the hand and wrist during attempts at maximum hand opening as well as reaching for four balls of different diameters. Our results showed that persons with SCI exhibited significantly reduced maximum hand aperture compared to able-bodied (AB) controls. However, persons with SCI preserved the ability to scale peak hand aperture with ball size during reaching. Persons with SCI also used distinct muscle coordination patterns that included increased co-activity of flexors and extensors at the wrist and hand compared to AB controls. These results suggest that motor planning for aperture modulation is preserved even though execution is limited by constraints on hand opening capacity and altered muscle co-activity. Thus, persons with incomplete cervical SCI may benefit from rehabilitation aimed at increasing hand opening capacity and reducing flexor-extensor co-activity at the wrist and hand. PMID:25511164
Optimum harvest maturity for Leymus chinensis seed.
Lin, Jixiang; Wang, Yingnan; Qi, Mingming; Li, Xiaoyu; Yang, Chunxue; Wang, Yongcui; Mu, Chunsheng
2016-06-15
Timely harvest is critical to achieve maximum seed viability and vigour in agricultural production. However, little information exists concerning how to reap the best quality seeds of Leymus chinensis, which is the dominant and most promising grass species in the Songnen Grassland of Northern China. The objective of this study was to investigate and evaluate possible quality indices of the seeds at different days after peak anthesis. Seed quality at different development stages was assessed by the colours of the seed and lemmas, seed weight, moisture content, electrical conductivity of seed leachate and germination indices. Two consecutive years of experimental results showed that the maximum seed quality was recorded at 39 days after peak anthesis. At this date, the colours of the seed and lemmas reached heavy brown and yellow, respectively. The seed weight was highest and the moisture content and the electrical conductivity of seed leachate were lowest. In addition, the seed also reached its maximum germination percentage and energy at this stage, determined using a standard germination test (SGT) and accelerated ageing test (AAT). Thus, Leymus chinensis can be harvested at 39 days after peak anthesis based on the changes in parameters. Colour identification can be used as an additional indicator to provide a more rapid and reliable measure of optimum seed maturity; approximately 10 days after the colour of the lemmas reached yellow and the colour of the seed reached heavy brown, the seed of this species was suitable for harvest. © 2016. Published by The Company of Biologists Ltd.
Optimum harvest maturity for Leymus chinensis seed
Lin, Jixiang; Wang, Yingnan; Qi, Mingming; Li, Xiaoyu; Yang, Chunxue; Wang, Yongcui
2016-01-01
ABSTRACT Timely harvest is critical to achieve maximum seed viability and vigour in agricultural production. However, little information exists concerning how to reap the best quality seeds of Leymus chinensis, which is the dominant and most promising grass species in the Songnen Grassland of Northern China. The objective of this study was to investigate and evaluate possible quality indices of the seeds at different days after peak anthesis. Seed quality at different development stages was assessed by the colours of the seed and lemmas, seed weight, moisture content, electrical conductivity of seed leachate and germination indices. Two consecutive years of experimental results showed that the maximum seed quality was recorded at 39 days after peak anthesis. At this date, the colours of the seed and lemmas reached heavy brown and yellow, respectively. The seed weight was highest and the moisture content and the electrical conductivity of seed leachate were lowest. In addition, the seed also reached its maximum germination percentage and energy at this stage, determined using a standard germination test (SGT) and accelerated ageing test (AAT). Thus, Leymus chinensis can be harvested at 39 days after peak anthesis based on the changes in parameters. Colour identification can be used as an additional indicator to provide a more rapid and reliable measure of optimum seed maturity; approximately 10 days after the colour of the lemmas reached yellow and the colour of the seed reached heavy brown, the seed of this species was suitable for harvest. PMID:27170257
Liu, Jian; Wu, Lihua; Wu, Guolan; Hu, Xingjiang; Zhou, Huili; Chen, Junchun; Zhu, Meixiang; Xu, Wei; Tan, Fenlai; Ding, Lieming; Wang, Yinxiang
2016-01-01
Lessons Learned This phase I study evaluated the maximum tolerated dose, dose-limiting toxicities, safety, pharmacokinetics, and efficacy of icotinib with a starting dose of 250 mg in pretreated, advanced non-small cell lung cancer patients. We observed a maximum tolerated dose of 500 mg with a favorable pharmacokinetics profile and antitumor activity. These findings provide clinicians with evidence for application of higher-dose icotinib. Background. Icotinib, an oral epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, has shown favorable tolerability and antitumor activity at 100–200 mg in previous studies without reaching the maximum tolerated dose (MTD). In July 2011, icotinib was approved by the China Food and Drug Administration at a dose of 125 mg three times daily for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) after failure of at least one platinum-based chemotherapy regimen. This study investigated the MTD, tolerability, and pharmacokinetics of higher-dose icotinib in patients with advanced NSCLC. Methods. Twenty-six patients with advanced NSCLC were treated at doses of 250–625 mg three times daily The EGFR mutation test was not mandatory in this study. Results. Twenty-four (92.3%) of 26 patients experienced at least one adverse event (AE); rash (61.5%), diarrhea (23.1%), and oral ulceration (11.5%) were most frequent AEs. Dose-limiting toxicities were seen in 2 of 6 patients in the 625-mg group, and the MTD was established at 500 mg. Icotinib was rapidly absorbed and eliminated. The amount of time that the drug was present at the maximum concentration in serum (Tmax) ranged from 1 to 3 hours (1.5–4 hours) after multiple doses. The t1/2 was similar after single- and multiple-dose administration (7.11 and 6.39 hours, respectively). A nonlinear relationship was observed between dose and drug exposure. Responses were seen in 6 (23.1%) patients, and 8 (30.8%) patients had stable disease. Conclusion. This study demonstrated that higher-dose icotinib was well-tolerated, with a MTD of 500 mg. Favorable antitumor activity and pharmacokinetic profile were observed in patients with heavily pretreated, advanced NSCLC. PMID:27789778
Liu, Jian; Wu, Lihua; Wu, Guolan; Hu, Xingjiang; Zhou, Huili; Chen, Junchun; Zhu, Meixiang; Xu, Wei; Tan, Fenlai; Ding, Lieming; Wang, Yinxiang; Shentu, Jianzhong
2016-11-01
This phase I study evaluated the maximum tolerated dose, dose-limiting toxicities, safety, pharmacokinetics, and efficacy of icotinib with a starting dose of 250 mg in pretreated, advanced non-small cell lung cancer patients. We observed a maximum tolerated dose of 500 mg with a favorable pharmacokinetics profile and antitumor activity.These findings provide clinicians with evidence for application of higher-dose icotinib. Icotinib, an oral epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, has shown favorable tolerability and antitumor activity at 100-200 mg in previous studies without reaching the maximum tolerated dose (MTD). In July 2011, icotinib was approved by the China Food and Drug Administration at a dose of 125 mg three times daily for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) after failure of at least one platinum-based chemotherapy regimen. This study investigated the MTD, tolerability, and pharmacokinetics of higher-dose icotinib in patients with advanced NSCLC. Twenty-six patients with advanced NSCLC were treated at doses of 250-625 mg three times daily The EGFR mutation test was not mandatory in this study. Twenty-four (92.3%) of 26 patients experienced at least one adverse event (AE); rash (61.5%), diarrhea (23.1%), and oral ulceration (11.5%) were most frequent AEs. Dose-limiting toxicities were seen in 2 of 6 patients in the 625-mg group, and the MTD was established at 500 mg. Icotinib was rapidly absorbed and eliminated. The amount of time that the drug was present at the maximum concentration in serum (T max ) ranged from 1 to 3 hours (1.5-4 hours) after multiple doses. The t 1/2 was similar after single- and multiple-dose administration (7.11 and 6.39 hours, respectively). A nonlinear relationship was observed between dose and drug exposure. Responses were seen in 6 (23.1%) patients, and 8 (30.8%) patients had stable disease. This study demonstrated that higher-dose icotinib was well-tolerated, with a MTD of 500 mg. Favorable antitumor activity and pharmacokinetic profile were observed in patients with heavily pretreated, advanced NSCLC. ©AlphaMed Press; the data published online to support this summary is the property of the authors.
Carvalho, Vitor Oliveira; Guimarães, Guilherme Veiga; Ciolac, Emmanuel Gomes; Bocchi, Edimar Alcides
2008-01-01
BACKGROUND Calculating the maximum heart rate for age is one method to characterize the maximum effort of an individual. Although this method is commonly used, little is known about heart rate dynamics in optimized beta-blocked heart failure patients. AIM The aim of this study was to evaluate heart rate dynamics (basal, peak and % heart rate increase) in optimized beta-blocked heart failure patients compared to sedentary, normal individuals (controls) during a treadmill cardiopulmonary exercise test. METHODS Twenty-five heart failure patients (49±11 years, 76% male), with an average LVEF of 30±7%, and fourteen controls were included in the study. Patients with atrial fibrillation, a pacemaker or noncardiovascular functional limitations or whose drug therapy was not optimized were excluded. Optimization was considered to be 50 mg/day or more of carvedilol, with a basal heart rate between 50 to 60 bpm that was maintained for 3 months. RESULTS Basal heart rate was lower in heart failure patients (57±3 bpm) compared to controls (89±14 bpm; p<0.0001). Similarly, the peak heart rate (% maximum predicted for age) was lower in HF patients (65.4±11.1%) compared to controls (98.6±2.2; p<0.0001). Maximum respiratory exchange ratio did not differ between the groups (1.2±0.5 for controls and 1.15±1 for heart failure patients; p=0.42). All controls reached the maximum heart rate for their age, while no patients in the heart failure group reached the maximum. Moreover, the % increase of heart rate from rest to peak exercise between heart failure (48±9%) and control (53±8%) was not different (p=0.157). CONCLUSION No patient in the heart failure group reached the maximum heart rate for their age during a treadmill cardiopulmonary exercise test, despite the fact that the percentage increase of heart rate was similar to sedentary normal subjects. A heart rate increase in optimized beta-blocked heart failure patients during cardiopulmonary exercise test over 65% of the maximum age-adjusted value should be considered an effort near the maximum. This information may be useful in rehabilitation programs and ischemic tests, although further studies are required. PMID:18719758
de Bruijn, Cornelis Marinus; Houterman, Willem; Ploeg, Margreet; Ducro, Bart; Boshuizen, Berit; Goethals, Klaartje; Verdegaal, Elisabeth-Lidwien; Delesalle, Catherine
2017-02-14
Most Friesian horses reach their anaerobic threshold during a standardized exercise test (SET) which requires lower intensity exercise than daily routine training. to study strengths and weaknesses of an alternative SET-protocol. Two different SETs (SETA and SETB) were applied during a 2 month training period of 9 young Friesian dressage horses. SETB alternated short episodes of canter with trot and walk, lacking long episodes of cantering, as applied in SETA. Following parameters were monitored: blood lactic acid (BLA) after cantering, average heart rate (HR) in trot and maximum HR in canter. HR and BLA of SETA and SETB were analyzed using a paired two-sided T-test and Spearman Correlation-coefficient (p* < 0.05). BLA after cantering was significantly higher in SETA compared to SETB and maximum HR in canter was significantly higher in SETA compared to SETB. The majority of horses showed a significant training response based upon longitudinal follow-up of BLA. Horses with the lowest fitness at start, displayed the largest training response. BLA was significantly lower in week 8 compared to week 0, in both SETA and SETB. A significantly decreased BLA level after cantering was noticeable in week 6 in SETA, whereas in SETB only as of week 8. In SETA a very strong correlation for BLA and average HR at trot was found throughout the entire training period, not for canter. Young Friesian horses do reach their anaerobic threshold during a SET which requires lower intensity than daily routine training. Therefore close monitoring throughout training is warranted. Longitudinal follow up of BLA and not of HR is suitable to assess training response. In the current study, horses that started with the lowest fitness level, showed the largest training response. During training monitoring HR in trot rather than in canter is advised. SETB is best suited as a template for daily training in the aerobic window.
Shang, Meng-Ying; Cao, Lin-Hong; Liu, Miao; Luo, Xuan; Ren, Hong-Bo; Ye, Xin; Tang, Yong-Jian; Jiang, Xiao-Dong
2013-04-01
Silica sol was prepared by acid catalyzed sol-gel process using tetraethylorthosilicate (TEOS) as precursor and dimethyldietoxysilane (DDS) as pore-forming agent. A novel kind of monolayer microporous silica anti-reflective (AR) coating was obtained on K9 glass substrate by dip-coating technique and then heat treated at 500 degrees C. The effects of different DDS/TEOS molar ratios on refractive index, transmittance and hardness were investigated. A positive correlation was found between the transmittance and the DDS/TEOS molar ratio due to the increasing porosity. The maximum transmittance can reach 99.7% with the molar ratio of DDS/TEOS rising to 1 : 1. Meanwhile, the refractive index was found quite close to the ideal value 1.22. Nevertheless, higher molar ratio will lead to a bad film-forming property. On the other hand, the hardness of the coatings decreased with the DDS increasing but still remained more than 2 h when the transmittance reached highest. Besides, these coatings exhibit a well abrasion-resistance and excellent adhesivity. The maximum transmittance was only dropped by 0.071% and 0.112% after abrasion for 500 and 1 000 times respectively. Accelerated corrosion tests indicated that the transmittance of traditional coatings rapidly fell down to the substrate level (-92%) after immersion for 5 min, while the transmittance of our novel coating almost linearly decreased and was kept 93.2% after 56 min. In other words, the environment-resistance of our novel silica AR coating is ten times higher than that of traditional ones. The promotions of the coating performances benefit from its micropore structure (-0. 4 nm) with which water molecule can be effectively prevented. With its high transmittance, good mechanical properties and high environment-resistance, this kind of novel coating has a potential application in the field of solar glass modification to improve its anti-reflective properties.
NASA Astrophysics Data System (ADS)
Kiaghadi, A.; Rifai, H. S.
2017-12-01
It is commonly believed that storm surge is the most destructive aspect of hurricanes. However, massive rainfall with a return period of 100 years or more induced by hurricanes can cause more catastrophic damage than losses caused by storm surge as demonstrated recently by hurricanes Harvey, Irma and Maria. In this study the hydrodynamics and environmental effects of hurricanes Ike and Harvey were compared and contrasted by linking hydrodynamic flow models with water quality models to simulate spills from storage tanks located in the Houston Ship Channel (HSC). Hurricane Ike with a maximum surge of 5.3 meters in Galveston Bay and Harvey with a maximum rainfall of 1.25 meters both struck the HSC region in Texas in 2008 and 2017, respectively. Both events resulted in numerous spills from municipal and industrial facilities, hazardous waste sites, superfund sites, and landfills. The Environmental Fluid Dynamic Code (EFDC) was coupled with the SWAN+ADCIRC hurricane simulation model to simulate Hurricane Ike and EFDC was coupled with USGS flow boundary conditions to model Hurricane Harvey. A conservative dye release was used to simulate a chemical release during each event. The results showed Hurricane Harvey caused higher water surface elevations within the HSC accompanied by longer and wider-spread land inundation. In contrast, higher water surface elevations were observed within the shallow side bays during Hurricane Ike that caused sediment resuspension and repartitioning of pollutants. Rapid spill mass transportation was observed for both hurricanes; 50% of total spill mass reached Galveston Bay in 20 and 22 hours after a spill event for Hurricane Harvey and Ike, respectively, and more than 90% of the spill mass reached the bay in 36 and 48 hours, respectively. Unlike Hurricane Harvey, the conservative tracer was spread almost 2.5 km upstream of the releasing point for Hurricane Ike due to surge. However, during Harvey, 35% more land was affected by the spilled mass with five times more remained mass on the land.
Chen, Yu-Yuan; Kitikiew, Suwaree; Yeh, Su-Tuen; Chen, Jiann-Chu
2016-12-01
White shrimp Litopenaeus vannamei receiving fucoidan at 2, 6, and 10 μg g -1 after 0-144 h or 0-120 h were examined for immune parameters (haemograms, phenoloxidase activity, respiratory burst, and superoxide dismutase activity), proliferation of haemocyte in the haematopoietic tissue (HPT), gene expression, and phagocytic activity and clearance efficiency to Vibrio alginolyticus. Immune parameters and mitotic index of HPT increased after 3-24 h, reached their maxima after 48-72 h, and returned to background values after 144 h. Transcripts of lipopolysaccharide and β-1,3-glucan binding protein (LGBP), peroxinectin (PX), prophenoloxidase (proPO) I, proPO II, astakine, and haemocyte homeostasis-associated protein (HHAP) were up-regulated to a maximum after 48-72 h and returned to background values after 144 h. Phagocytic activity and clearance efficiency to V. alginolyticus increased after 12 h, reached its maximum after 48 h, and continued to remain higher after 120 h. In another experiment, shrimp receiving fucoidan after 48 h and 144 h were respectively challenged with V. alinolyticus at 6 × 10 6 colony-forming units (cfu) shrimp -1 or challenged with WSSV at 1.2 × 10 5 copies shrimp -1 and then placed in seawater. The survival rate of shrimp receiving fucoidan was significantly higher than in controls. In conclusion, shrimp receiving fucoidan showed a proliferation of HPT, increased immune parameters, and up-regulated transcripts of LGBP, PX, proPO I, proPO II, astakine, and HHAP after 48 h. Shrimp receiving fucoidan exhibited a defense against V. alginolyticus and WSSV, even after immune parameters recovered to background levels. Copyright © 2016 Elsevier Ltd. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Silva, D; Salmon, H; Pavan, G
2014-06-01
Purpose: Evaluate and compare retrospective prostate treatment plan using Volumetric Modulated Arc Therapy (RapidArc™ - Varian) technique with single or double arcs at COI Group. Methods: Ten patients with present prostate and seminal vesicle neoplasia were replanned as a target treatment volume and a prescribed dose of 78 Gy. A baseline planning, using single arc, was developed for each case reaching for the best result on PTV, in order to minimize the dose on organs at risk (OAR). Maintaining the same optimization objectives used on baseline plan, two copies for optimizing single and double arcs, have been developed. The plansmore » were performed with 10 MV photon beam energy on Eclipse software, version 11.0, making use of Trilogy linear accelerator with Millenium HD120 multileaf collimator. Comparisons on PTV have been performed, such as: maximum, minimum and mean dose, gradient dose, as well as the quantity of monitor units, treatment time and homogeneity and conformity index. OARs constrains dose have been evaluated, comparing both optimizations. Results: Regarding PTV coverage, the difference of the minimum, maximum and mean dose were 1.28%, 0.7% and 0.2% respectively higher for single arc. When analyzed the index of homogeneity found a difference of 0.99% higher when compared with double arcs. However homogeneity index was 0.97% lower on average by using single arc. The doses on the OARs, in both cases, were in compliance to the recommended limits RTOG 0415. With the use of single arc, the quantity of monitor units was 10,1% lower, as well as the Beam-On time, 41,78%, when comparing double arcs, respectively. Conclusion: Concerning the optimization of patients with present prostate and seminal vesicle neoplasia, the use of single arc reaches similar objectives, when compared to double arcs, in order to decrease the treatment time and the quantity of monitor units.« less
NASA Astrophysics Data System (ADS)
D'Amboise, Christopher J. L.; Müller, Karsten; Oxarango, Laurent; Morin, Samuel; Schuler, Thomas V.
2017-09-01
We present a new water percolation routine added to the one-dimensional snowpack model Crocus as an alternative to the empirical bucket routine. This routine solves the Richards equation, which describes flow of water through unsaturated porous snow governed by capillary suction, gravity and hydraulic conductivity of the snow layers. We tested the Richards routine on two data sets, one recorded from an automatic weather station over the winter of 2013-2014 at Filefjell, Norway, and the other an idealized synthetic data set. Model results using the Richards routine generally lead to higher water contents in the snow layers. Snow layers often reached a point at which the ice crystals' surface area is completely covered by a thin film of water (the transition between pendular and funicular regimes), at which feedback from the snow metamorphism and compaction routines are expected to be nonlinear. With the synthetic simulation 18 % of snow layers obtained a saturation of > 10 % and 0.57 % of layers reached saturation of > 15 %. The Richards routine had a maximum liquid water content of 173.6 kg m-3 whereas the bucket routine had a maximum of 42.1 kg m-3. We found that wet-snow processes, such as wet-snow metamorphism and wet-snow compaction rates, are not accurately represented at higher water contents. These routines feed back on the Richards routines, which rely heavily on grain size and snow density. The parameter sets for the water retention curve and hydraulic conductivity of snow layers, which are used in the Richards routine, do not represent all the snow types that can be found in a natural snowpack. We show that the new routine has been implemented in the Crocus model, but due to feedback amplification and parameter uncertainties, meaningful applicability is limited. Updating or adapting other routines in Crocus, specifically the snow compaction routine and the grain metamorphism routine, is needed before Crocus can accurately simulate the snowpack using the Richards routine.
Jiyane, Phiwe Charles; Tumba, Kaniki; Musonge, Paul
2018-04-01
The extraction of oil from Croton gratissimus seeds was studied using the three-factor five-level full-factorial central composite rotatable design (CCRD) of the response surface methodology (RSM). The effect of the three factors selected, viz., extraction time, extraction temperature and solvent-to-feed ratio on the extraction oil yield was investigated when n-hexane and ethyl acetate were used as extraction solvents. The coefficients of determination (R 2 ) of the models developed were 0.98 for n-hexane extraction and 0.97 for ethyl acetate extraction. These results demonstrated that the models developed adequately represented the processes they described. From the optimized model, maximum extraction yield obtained from n-hexane and ethyl acetate extraction were 23.88% and 23.25%, respectively. In both cases the extraction temperature and solvent-to-feed ratio were 35°C and 5 mL/g, respectively. In n-hexane extraction the maximum conditions were reached only after 6 min whereas in ethyl acetate extraction it took 20 min to get the maximum extraction oil yield. Oil extraction of Croton gratissimus seeds, in this work, favoured the use of n-hexane as an extraction solvent as it offered higher oil yields at low temperatures and reduced residence times.
Electron density and plasma dynamics of a colliding plasma experiment
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wiechula, J., E-mail: wiechula@physik.uni-frankfurt.de; Schönlein, A.; Iberler, M.
2016-07-15
We present experimental results of two head-on colliding plasma sheaths accelerated by pulsed-power-driven coaxial plasma accelerators. The measurements have been performed in a small vacuum chamber with a neutral-gas prefill of ArH{sub 2} at gas pressures between 17 Pa and 400 Pa and load voltages between 4 kV and 9 kV. As the plasma sheaths collide, the electron density is significantly increased. The electron density reaches maximum values of ≈8 ⋅ 10{sup 15} cm{sup −3} for a single accelerated plasma and a maximum value of ≈2.6 ⋅ 10{sup 16} cm{sup −3} for the plasma collision. Overall a raise of the plasma density by a factor ofmore » 1.3 to 3.8 has been achieved. A scaling behavior has been derived from the values of the electron density which shows a disproportionately high increase of the electron density of the collisional case for higher applied voltages in comparison to a single accelerated plasma. Sequences of the plasma collision have been taken, using a fast framing camera to study the plasma dynamics. These sequences indicate a maximum collision velocity of 34 km/s.« less
Efficiency at maximum power of low-dissipation Carnot engines.
Esposito, Massimiliano; Kawai, Ryoichi; Lindenberg, Katja; Van den Broeck, Christian
2010-10-08
We study the efficiency at maximum power, η*, of engines performing finite-time Carnot cycles between a hot and a cold reservoir at temperatures Th and Tc, respectively. For engines reaching Carnot efficiency ηC=1-Tc/Th in the reversible limit (long cycle time, zero dissipation), we find in the limit of low dissipation that η* is bounded from above by ηC/(2-ηC) and from below by ηC/2. These bounds are reached when the ratio of the dissipation during the cold and hot isothermal phases tend, respectively, to zero or infinity. For symmetric dissipation (ratio one) the Curzon-Ahlborn efficiency ηCA=1-√Tc/Th] is recovered.
Piezoelectric properties of synthetic hydroxyapatite-based organic-inorganic hydrated materials
NASA Astrophysics Data System (ADS)
Rodriguez, Rogelio; Rangel, Domingo; Fonseca, Gerardo; Gonzalez, Maykel; Vargas, Susana
Disks of synthetic hydroxyapatite agglutinated with a synthetic polymer and hydrated in a moisture fog, were prepared. A well-defined piezoelectric signal of these samples was obtained when a relative small compression stress of 35 MPa (corresponding a force of 450 daN) was applied; piezoelectric signals of up to 12 mV were obtained with this stress. Two different compression methods were followed to obtain the piezoelectric signal: (a) hold method, where the load was maintained constant once it reaches the maximum stress and (b) release method, where the load was removed rapidly when the stress reaches its maximum value. The samples were characterized using the techniques: X-ray Diffraction, Dielectric Relaxation Spectroscopy and mechanical test.
Mutually unbiased bases in six dimensions: The four most distant bases
DOE Office of Scientific and Technical Information (OSTI.GOV)
Raynal, Philippe; Lue Xin; Englert, Berthold-Georg
2011-06-15
We consider the average distance between four bases in six dimensions. The distance between two orthonormal bases vanishes when the bases are the same, and the distance reaches its maximal value of unity when the bases are unbiased. We perform a numerical search for the maximum average distance and find it to be strictly smaller than unity. This is strong evidence that no four mutually unbiased bases exist in six dimensions. We also provide a two-parameter family of three bases which, together with the canonical basis, reach the numerically found maximum of the average distance, and we conduct a detailedmore » study of the structure of the extremal set of bases.« less
NASA Astrophysics Data System (ADS)
Stergiopoulos, Ch.; Stavrakas, I.; Triantis, D.; Vallianatos, F.; Stonham, J.
2015-02-01
Weak electric signals termed as 'Pressure Stimulated Currents, PSC' are generated and detected while cement based materials are found under mechanical load, related to the creation of cracks and the consequent evolution of cracks' network in the bulk of the specimen. During the experiment a set of cement mortar beams of rectangular cross-section were subjected to Three-Point Bending (3PB). For each one of the specimens an abrupt mechanical load step was applied, increased from the low load level (Lo) to a high final value (Lh) , where Lh was different for each specimen and it was maintained constant for long time. The temporal behavior of the recorded PSC show that during the load increase a spike-like PSC emission was recorded and consequently a relaxation of the PSC, after reaching its final value, follows. The relaxation process of the PSC was studied using non-extensive statistical physics (NESP) based on Tsallis entropy equation. The behavior of the Tsallis q parameter was studied in relaxation PSCs in order to investigate its potential use as an index for monitoring the crack evolution process with a potential use in non-destructive laboratory testing of cement-based specimens of unknown internal damage level. The dependence of the q-parameter on the Lh (when Lh <0.8Lf), where Lf represents the 3PB strength of the specimen, shows an increase on the q value when the specimens are subjected to gradually higher bending loadings and reaches a maximum value close to 1.4 when the applied Lh becomes higher than 0.8Lf. While the applied Lh becomes higher than 0.9Lf the value of the q-parameter gradually decreases. This analysis of the experimental data manifests that the value of the entropic index q obtains a characteristic decrease while reaching the ultimate strength of the specimen, and thus could be used as a forerunner of the expected failure.
Rijgersberg, Hajo; Franz, Eelco; Nierop Groot, Masja; Tromp, Seth-Oscar
2013-07-01
Within a microbial risk assessment framework, modeling the maximum population density (MPD) of a pathogenic microorganism is important but often not considered. This paper describes a model predicting the MPD of Salmonella on alfalfa as a function of the initial contamination level, the total count of the indigenous microbial population, the maximum pathogen growth rate and the maximum population density of the indigenous microbial population. The model is parameterized by experimental data describing growth of Salmonella on sprouting alfalfa seeds at inoculum size, native microbial load and Pseudomonas fluorescens 2-79. The obtained model fits well to the experimental data, with standard errors less than ten percent of the fitted average values. The results show that the MPD of Salmonella is not only dictated by performance characteristics of Salmonella but depends on the characteristics of the indigenous microbial population like total number of cells and its growth rate. The model can improve the predictions of microbiological growth in quantitative microbial risk assessments. Using this model, the effects of preventive measures to reduce pathogenic load and a concurrent effect on the background population can be better evaluated. If competing microorganisms are more sensitive to a particular decontamination method, a pathogenic microorganism may grow faster and reach a higher level. More knowledge regarding the effect of the indigenous microbial population (size, diversity, composition) of food products on pathogen dynamics is needed in order to make adequate predictions of pathogen dynamics on various food products.
Testing of two different strains of green microalgae for Cu and Ni removal from aqueous media.
Rugnini, L; Costa, G; Congestri, R; Bruno, L
2017-12-01
The concentration of metal ions in aqueous media is a major environmental problem due to their persistence and non-biodegradability that poses hazards to the ecosystem and human health. In this study, the effect of Cu and Ni on the growth of two green microalgal strains, Chlorella vulgaris and Desmodesmus sp., was evaluated along with the removal capacity from single metal solutions (12days exposure; metal concentration range: 1.9-11.9mgL -1 ). Microalgal growth showed to decrease at increasing metal concentrations, but promising metal removal efficiencies were recorded: up to 43% and 39% for Cu by Desmodesmus sp. and C. vulgaris, respectively, with a sorption capacity of 33.4mggDW -1 for Desmodesmus sp. As for Ni, at the concentration of 5.7mgL -1 , the removal efficiency reached 32% for C. vulgaris and 39% for Desmodesmus sp. In addition, Desmodesmus sp. growth and metal removal were evaluated employing bimetallic solutions. In these tests, the removal efficiency for Cu was higher than that of Ni for all the mix solutions tested with a maximum of 95%, while Ni-removal reached 90% only for the lowest concentrations tested. Results revealed that the biosorption of both metals reached maximum removal levels within the fourth day of incubation (with metal uptakes of 67mgCugDW -1 and 37mgNigDW -1 ). Intracellular bioaccumulation of metals in Desmodesmus sp. was evaluated by confocal laser scanning microscopy after DAPI staining of cells exposed or not to Cu during their growth. Imaging suggested that Cu is sequestered in polyphosphate bodies within the cells, as observable also in phosphorus deprived cultures. Our results indicate the potential of employing green microalgae for bioremediation of metal-polluted waters, due to their ability to grow in the presence of high metal concentrations and to remove them efficiently. Copyright © 2017 Elsevier B.V. All rights reserved.
Patel, Priya; Wada, Hironobu; Hu, Hsin-Pei; Hirohashi, Kentaro; Kato, Tatsuya; Ujiie, Hideki; Ahn, Jin Young; Lee, Daiyoon; Geddie, William; Yasufuku, Kazuhiro
2017-04-01
Endobronchial ultrasonography (EBUS)-guided transbronchial needle aspiration allows for sampling of mediastinal lymph nodes. The external diameter, rigidity, and angulation of the convex probe EBUS renders limited accessibility. This study compares the accessibility and transbronchial needle aspiration capability of the prototype thin convex probe EBUS against the convex probe EBUS in human ex vivo lungs rejected for transplant. The prototype thin convex probe EBUS (BF-Y0055; Olympus, Tokyo, Japan) with a thinner tip (5.9 mm), greater upward angle (170 degrees), and decreased forward oblique direction of view (20 degrees) was compared with the current convex probe EBUS (6.9-mm tip, 120 degrees, and 35 degrees, respectively). Accessibility and transbronchial needle aspiration capability was assessed in ex vivo human lungs declined for lung transplant. The distance of maximum reach and sustainable endoscopic limit were measured. Transbronchial needle aspiration capability was assessed using the prototype 25G aspiration needle in segmental lymph nodes. In all evaluated lungs (n = 5), the thin convex probe EBUS demonstrated greater reach and a higher success rate, averaging 22.1 mm greater maximum reach and 10.3 mm further endoscopic visibility range than convex probe EBUS, and could assess selectively almost all segmental bronchi (98% right, 91% left), demonstrating nearly twice the accessibility as the convex probe EBUS (48% right, 47% left). The prototype successfully enabled cytologic assessment of subsegmental lymph nodes with adequate quality using the dedicated 25G aspiration needle. Thin convex probe EBUS has greater accessibility to peripheral airways in human lungs and is capable of sampling segmental lymph nodes using the aspiration needle. That will allow for more precise assessment of N1 nodes and, possibly, intrapulmonary lesions normally inaccessible to the conventional convex probe EBUS. Copyright © 2017 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
Tretriluxana, Jarugool; Runnarong, Nuttakarn; Tretriluxana, Suradej; Prayoonwiwat, Naraporn; Vachalathiti, Roongtiwa; Winstein, Carolee
2013-01-01
Skill acquisition, capacity building, and motivational enhancements are the basis of the Accelerated Skill Acquisition Program (ASAP) and form the foundation for effective incorporation of the paretic upper extremity into life activities. This is the first phase I trial to deliver ASAP during the postacute interval in mildly to moderately impaired stroke survivors and to include an assessment of paretic reach-to-grasp (RTG) coordination using RTG task and cross-correlation analyses. Two baseline and posttreatment evaluations consisted of RTG actions, the Wolf Motor Function Test (WMFT), and the Stroke Impact Scale (SIS). An individualized arm therapy program using ASAP principles was administered for a total of 30 hours, 2 hours per day, for 2 to 4 days per week over 5 weeks. Dependent measures were kinematics of RTG actions, RTG coordination, total time score of WMFT, and stroke recovery score of SIS. All participants tolerated ASAP well, and none reported any adverse effects during or after the protocol. When the 2 baseline evaluations were compared, there were no changes in any RTG kinematics or RTG coordination. In contrast, after 30 hours of ASAP, total movement time and deceleration time of RTG actions markedly decreased, maximum reach (transport) velocity strikingly increased, and time of maximum aperture was accomplished later. Additionally, the maximal RTG correlation coefficient increased with a shorter associated time lag. A similar pattern was observed for the clinical outcome measures of WMFT and SIS. The findings demonstrate the feasibility of using an ASAP protocol for patients 1 to 3 months post stroke. Under ASAP, WMFT tasks and RTG actions were performed faster with higher peak transport velocity and a more coordinated RTG pattern. The next step is to determine whether the immediate gains in the skilled RTG actions persist 6 months alter.
NASA Astrophysics Data System (ADS)
Domino, Krzysztof
2012-01-01
The WIG20 index-the index of the 20 biggest companies traded on the Warsaw Stock Exchange-reached the global maximum on 29th October 2007. I have used the local DFA (Detrended Functional Analysis) to obtain the Hurst exponent (diffusion exponent) and investigate the signature of anti-correlation of share price evolution around the maximum. The analysis was applied to the share price evolution for variable DFA parameters. For many values of parameters, the evidence of anti-correlation near the WIG20 maximum was pointed out.
Ozeki, K; Aoki, H
2016-08-12
Removal of radioactive substances, such as cesium (Cs) and strontium (Sr), has become an emerging issue after the Fukushima Daiichi Nuclear Power Plant Disaster. To assess the possibility that hydroxyapatite (HA) and zeolites can be used for removal of radioactive substances, the adsorption capacities of Cs and Sr on the HA and a zeolite were investigated. The influence of Fe ions on Cs and Sr adsorption on the HA and the zeolite was also evaluated, because Fe ions are the most effective inhibitor of Cs adsorption on the zeolite.In the Cs adsorption process on the HA and the zeolite, the zeolite showed a higher adsorption ratio than the HA, and the maximum sorption capacity of the zeolite was calculated as 196 mg/g, whereas the HA showed a higher Sr adsorption ratio than the zeolite. The maximum sorption capacity of Sr on the HA was 123 mg/g. Under coexistence with Fe, Cs adsorption on the zeolite decreased with increasing Fe concentration, reaching 2.0 ± 0.8% at 0.1 M Fe concentration. In contrast, Cs adsorption on the zeolite was improved by adding the HA. In the case of coexistence of the HA, the Cs adsorption on the mixture of the HA and the zeolite was 52.4% ± 3.6 % at 0.1 M Fe concentration, although Cs adsorption on the HA alone was quite low. In the Fe adsorption processes of the HA and the zeolite, the HA exhibited a maximum sorption capacity of 256 mg/g, which was much higher than that of the zeolite (111 mg/g). The high affinity of Fe on the HA contributes to the improvement of the deteriorated Cs adsorption on the zeolite due to Fe ions.
Dan, Abhijit; Gochev, Georgi; Miller, Reinhard
2015-07-01
Oscillating drop tensiometry was applied to study adsorbed interfacial layers at water/air and water/hexane interfaces formed from mixed solutions of β-lactoglobulin (BLG, 1 μM in 10 mM buffer, pH 7 - negative net charge) and the anionic surfactant SDS or the cationic DoTAB. The interfacial pressure Π and the dilational viscoelasticity modulus |E| of the mixed layers were measured for mixtures of varying surfactant concentrations. The double capillary technique was employed which enables exchange of the protein solution in the drop bulk by surfactant solution (sequential adsorption) or by pure buffer (washing out). The first protocol allows probing the influence of the surfactant on a pre-adsorbed protein layer thus studying the protein/surfactant interactions at the interface. The second protocol gives access to the residual values of Π and |E| measured after the washing out procedure thus bringing information about the process of protein desorption. The DoTAB/BLG complexes exhibit higher surface activity and higher resistance to desorption in comparison with those for the SDS/BLG complexes due to hydrophobization via electrostatic binding of surfactant molecules. The neutral DoTAB/BLG complexes achieve maximum elastic response of the mixed layer. Mixed BLG/surfactant layers at the water/oil interface are found to reach higher surface pressure and lower maximum dilational elasticity than those at the water/air surface. The sequential adsorption mode experiments and the desorption study reveal that binding of DoTAB to pre-adsorbed BLG globules is somehow restricted at the water/air surface in comparison with the case of complex formation in the solution bulk and subsequently adsorbed at the water/air surface. Maximum elasticity is achieved with washed out layers obtained after simultaneous adsorption, i.e. isolation of the most surface active DoTAB/BLG complex. These specific effects are much less pronounced at the W/H interface. Copyright © 2015 Elsevier Inc. All rights reserved.
Zerrouki, A; Salar-García, M J; Ortiz-Martínez, V M; Guendouz, S; Ilikti, H; de Los Ríos, A P; Hernández-Fernández, F J; Kameche, M
2018-03-05
Microbial fuel cells (MFCs) are a promising technology that generates electricity from several biodegradable substrates and wastes. The main drawback of these devices is the need of using a catalyst for the oxygen reduction reaction at the cathode, which makes the process relatively expensive. In this work, two low cost materials are tested as catalysts in MFCs. A novel iron complex based on the ligand n-phenyledenparaethoxy aniline has been synthesized and its performance as catalyst in single chamber MFCs containing ionic liquids has been compared with a commercial inorganic material such as Raney nickel. The results show that both materials are suitable for bioenergy production and wastewater treatment in the systems. Raney nickel cathodes allow MFCs to reach a maximum power output of 160 mW.m -3 anode , while the iron complex offers lower values. Regarding the wastewater treatment capacity, MFCs working with Raney nickel-based cathodes reach higher values of chemical oxygen demand removal (76%) compared with the performance displayed by the cathodes based on Fe-complex (56%).
Fayed, Bahgat; Abood, Amira; El-Sayed, Hoda S; Hashem, Amal M; Mehanna, Nayra S H
2018-08-01
A novel synbiotic multiparticulate microparticle was produced in the current study to expand the synbiotic industrial applications. Initially, the inulin was fabricated into PLGA nanoparticles. After the inulin entrapment efficiency was boosted to reach 92.9 ± 8.4% by adjusting the formulation parameters, the developed particles were characterized by different techniques such as particle size analyzer, TEM, and TLC. The obtained data showed that the particle size was 115.8 ± 82.7 nm, the particles had smooth surface and round shape, and the fabrication procedure did not affect the integrity of the inulin. Later, the inulin loaded nanoparticles together with selected Bifidobacterium species were double coated with gum arabic and alginate. The maximum survivability of the encapsulated Bifidobacterium in the simulated gastric solution reached 88.29% of the initial population, which was significantly higher than the survivability of the free bacteria. Finally, the inulin release from the multiparticulate microparticles was studied and found to be sustained over three days. Copyright © 2018 Elsevier Ltd. All rights reserved.
SANS Investigations of CO 2 Adsorption in Microporous Carbon
Bahadur, Jitendra; Melnichenko, Yuri B.; He, Lilin; ...
2015-08-07
The high pressure adsorption behavior of CO 2 at T = 296 K in microporous carbon was investigated by small-angle neutron scattering (SANS) technique. A strong densification of CO 2 in micropores accompanied by non-monotonic adsorption-induced pore deformation was observed. The density of confined CO 2 increases rapidly with pressure and reaches the liquid –like density at 20 bar, which corresponds to the relative pressure of P/Psat ~0.3. At P > 20 bar density of confined CO 2 increases slowly approaching a plateau at higher pressure. The size of micropores first increases with pressure, reaches amore » maximum at 20 bar, and then decreases with pressure. A complementary SANS experiment conducted on the same microporous carbon saturated with neutron-transparent and non-adsorbing inert gas argon shows no deformation of micropores at pressures up to ~200 bars. This result demonstrates that the observed deformation of micropores in CO 2 is an adsorption-induced phenomenon, caused by the solvation pressure - induced strain and strong densification of confined CO 2 .« less
SANS Investigations of CO 2 Adsorption in Microporous Carbon
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bahadur, Jitendra; Melnichenko, Yuri B.; He, Lilin
The high pressure adsorption behavior of CO 2 at T = 296 K in microporous carbon was investigated by small-angle neutron scattering (SANS) technique. A strong densification of CO 2 in micropores accompanied by non-monotonic adsorption-induced pore deformation was observed. The density of confined CO 2 increases rapidly with pressure and reaches the liquid –like density at 20 bar, which corresponds to the relative pressure of P/Psat ~0.3. At P > 20 bar density of confined CO 2 increases slowly approaching a plateau at higher pressure. The size of micropores first increases with pressure, reaches amore » maximum at 20 bar, and then decreases with pressure. A complementary SANS experiment conducted on the same microporous carbon saturated with neutron-transparent and non-adsorbing inert gas argon shows no deformation of micropores at pressures up to ~200 bars. This result demonstrates that the observed deformation of micropores in CO 2 is an adsorption-induced phenomenon, caused by the solvation pressure - induced strain and strong densification of confined CO 2 .« less
Occurrence of Organic Contaminants in Lower Reaches of River Ganges, India
NASA Astrophysics Data System (ADS)
Dutta Gupta, S.; Bhattacharya, A.; Mukherjee, A.; Bhattacharya, J.
2016-12-01
The Gangetic plain of eastern India has been long known as the "bread basket" of the Indian subcontinent. However, indiscriminate use of pesticides in the agricultural fields is to increase crop production. These resulted to increased vulnerability of pesticide pollution of the hydrological systems of the area, potentially exposing to significant human health consequences. Our present study delineate pesticides occurrence in lower Ganges in West Bengal. The major organic contaminants regularly detected in the studied reaches of the Ganges belong to wide range of herbicides and insecticides, which especially include organochlorides and organophosphates such as Aldrin, Alachlor, Lindane, Malathion, Chlorpyrifos and Methyl parathion. Results show Alachlor and Malathion were the most abundant organic contaminant in the river. Among the other pesticides, one of the most venomous substances, Malathion has been noticed from the last year insecticide screening study. The mean concentration of river water Malathion was found to be 5 times higher than the maximum concentration limit (MCL). Presence of Malathion or its derivative Malaoxon in river water is suspected to be caused by agricultural run-off and it showed a good correlation with river water chlorine concentrations.
NASA Astrophysics Data System (ADS)
Rutberg, Ph G.; Popov, S. D.; Surov, A. V.; Serba, E. O.; Nakonechny, Gh V.; Spodobin, V. A.; Pavlov, A. V.; Surov, A. V.
2012-12-01
The comparison of conductivity obtained in experiments with calculated values is made in this paper. Powerful stationary plasma torches with prolonged period of continuous work are popular for modern plasmachemical applications. The maximum electrode lifetime with the minimum erosion can be reached while working on rather low currents. Meanwhile it is required to provide voltage arc drop for the high power achievement. Electric field strength in the arc column of the high-voltage plasma torch, using air as a plasma-forming gas, does not exceed 15 V/cm. It is possible to obtain the high voltage drop in the long arc stabilized in the channel by the intensive gas flow under given conditions. Models of high voltage plasma torches with rod electrodes with power up to 50 kW have been developed and investigated. The plasma torch arcs are burning in cylindrical channels. Present investigations are directed at studying the possibility of developing long arc plasma torches with higher power. The advantage of AC power supplies usage is the possibility of the loss minimization due to the reactive power compensation. The theoretical maximum of voltage arc drop for power supplies with inductive current limitations is about 50 % of the no-load voltage for a single-phase circuit and about 30 % for the three-phase circuit. Burning of intensively blown arcs in the long cylindrical channel using the AC power supply with 10 kV no-load voltage is experimentally investigated in the work. Voltage drops close to the maximum possible had been reached in the examined arcs in single-phase and three-phase modes. Operating parameters for single-phase mode were: current -30 A, voltage drop -5 kV, air flow rate 35 g/s; for three-phase mode: current (40-85) A, voltage drop (2.5-3.2) kV, air flow rate (60-100) g/s. Arc length in the installations exceeded 2 m.
Kumbhakar, N K; Sanyal, P K; Rawte, D; Kumar, D; Kerketta, A E; Pal, S
2016-09-01
To test the hypothesis that modulation of hepatic microsomal sulphoxidation and sulphonation by the cytochrome P450 inhibitor piperonyl butoxide could increase bioavailability of albendazole, the present study was undertaken to understand the pharmacokinetics of albendazole in goats at a dose of 7.5 mg kg- 1 body weight with and without co-administration with piperonyl butoxide at 63.0 mg kg- 1 body weight. Plasma albendazole sulphoxide metabolite, the anthelmintically active moiety, reached its maximum concentration of 0.322 ± 0.045 μg ml- 1 and 0.384 ± 0.013 μg ml- 1 at 18 h and 24 h after administration of albendazole alone and co-administration of albendazole with piperonyl butoxide, respectively. Analysis of the data revealed statistically increased albendazole sulphoxide levels at 24 (P 0.05) in values of maximum concentration (normal and calculated) could be observed between groups of goats. However, values of time to reach the concentration maximum (normal and calculated), area under the concentration-time curve (0-∞ and calculated), minimum residence time, distribution half-life, elimination half-life and total area under the first movement of plasma drug concentration-time curve were significantly higher (P < 0.05) in plasma levels of albendazole sulphoxide in goats following single oral co-administration of albendazole with piperonyl butoxide. The faecal egg count reduction and lower 95% confidence limit for the group treated with albendazole alone were 97 and 68%, while for co-administration of albendazole and piperonyl butoxide the values were 99 and 97%, respectively. The ED50 for egg hatch was 0.196, indicating suspected resistance to benzimidazole anthelmintics. The drug combination proved efficacious against an albendazole-resistant nematode parasite population in goats.
NASA Astrophysics Data System (ADS)
Tesfuhuney, Weldemichael A.; Walker, Sue; Van Rensburg, Leon D.; Steyn, A. Stephan
2016-08-01
In a cropped field, microclimate and thermal stability conditions depend on the canopy structures and the prevailing weather. The main aim of the study therefore was to characterize the vertical profiles of weather variables within and above a maize (Zea mays L.) canopy and to describe the water vapour pressure deficit (VPD) under different atmospheric and soil surface conditions for both wide and narrow runoff strips with the in-field rainwater harvesting (IRWH) system. Micrometeorological measurements of wind, temperature and relative humidity were performed at eight levels, within canopy (1.8 and 2.1 m), and just above the canopy (2.4, 2.7, 3.0, and 3.3 m) up to reference levels (3.9 and 4.5 m) when the maize reached a maximum height of 2.2 m. Under incomplete canopy cover of the IRWH system, two important factors complicated evapotranspiration estimation, namely the local advection and high temperatures of the bare soil between adjacent plant rows. Diurnal variations of water vapour related to turbulence at each locality and its position in the thermal internal boundary layers. Generally, advection was more pronounced in wide runoff strips than narrow strips. On wide runoff strips the wind was more effective in replacing the air between the rows and maintained a higher driving force for evaporation. The maximum VPD over the narrow strips was observed at reference level during a dry day, at about 2.2 kPa in the afternoon, while wet day VPD reached a maximum of 1.8 kPa. The VPD of the wide runoff strips correlated negatively with wind speed, but showed a fairly positive correlation with some scattered values on wet days after rain. Therefore, profile characteristics within and above plant canopies played a key role in determining the VPD and consequently, could help to explain transpiration rates of crops. Hence, VPD relations enhanced the understanding of the heat energy exchange processes under the heterogeneous nature of maize canopy of the IRWH tillage system.
Explosion hazards of LPG-air mixtures in vented enclosure with obstacles.
Zhang, Qi; Wang, Yaxing; Lian, Zhen
2017-07-15
Numerical simulations were performed to study explosion characteristics of liquefied petroleum gas (LPG) explosion in enclosure with a vent. Unlike explosion overpressure and dynamic pressure, explosion temperature of the LPG-air mixture at a given concentration in a vented enclosure has very little variation with obstacle numbers for a given blockage ratio. For an enclosure without obstacle, explosion overpressures for the stoichiometric mixtures and the fuel-lean mixtures reach their maximum within the vent and that for fuel-rich mixture reaches its maximum beyond and near the vent. Dynamic pressures produced by an indoor LPG explosion reach their maximum always beyond the vent no matter obstacles are present or not in the enclosure. A LPG explosion in a vented enclosure with built-in obstacles is strong enough to make the brick and mortar wall with a thickness of 370mm damaged. If there is no obstacle in the enclosure, the lower explosion pressure of several kPa can not break the brick and mortar wall with a thickness of 370mm. For a LPG explosion produced in an enclosure with a vent, main hazards, within the vent, are overpressure and high temperature. However main hazards are dynamic pressure, blast wind, and high temperature beyond the vent. Copyright © 2017 Elsevier B.V. All rights reserved.
Martins, Rui C; Ferreira, Ana M; Gando-Ferreira, Licínio M; Quinta-Ferreira, Rosa M
2015-10-01
With the objective of reaching suitable techniques for olive mill wastewater treatment, ozonation and ultrafiltration were studied individually and combined. A continuous reactor was run for the treatment of a phenolic mixture mimicking an actual olive mill wastewater (OMW) by ozonation. The effect of the main operating parameters was analysed (pH, liquid flow rate and ozone inlet concentration). The increase of pH and ozone dose improved ozonation efficiency. As expected, the highest residence time led to higher steady-state degradation (35 % of chemical oxygen demand (COD) abatement). Even if the rise on ozone inlet gas concentration was able to remove COD in a higher extent, it should be taken into consideration that with the lowest oxidant load (15 g O3/m(3)), the maximum steady-state biochemical oxygen demand (BOD5)/COD ratio was reached which would reduce the process costs. These operating conditions (pH 9, 1 mL/min of liquid flow rate and 15 g O3/m(3)) were applied to an actual OMW leading to 80 % of phenolic content abatement and 12 % of COD removal at the steady state. Regarding ultrafiltration, it was concluded that the best total phenolic content (TPh) and COD abatement results (55 and 15 %) are attained for pH 9 and using a transmembrane pressure drop of 1 bar. Among the integration schemes that were tested, ultrafiltration followed by ozonation was able to reach 93 and 20 % of TPh and COD depletion, respectively. Moreover, this sequence led to an effluent with a BOD5/COD ratio of about 0.55 which means that it likely can be posteriorly refined in a municipal wastewater treatment plant.
Radio Astronomy Explorer (RAE) 1 observations of terrestrial radio noise
NASA Technical Reports Server (NTRS)
Herman, J. R.; Caruso, J. A.
1971-01-01
Radio Astonomy Explorer (RAE) 1 data are analyzed to establish characteristics of HF terrestrial radio noise at an altitude of about 6000 km. Time and frequency variations in amplitude of the observed noise well above cosmic noise background are explained on the basis of temporal and spatial variations in ionospheric critical frequency coupled with those in noise source distributions. It is shown that terrestrial noise regularly breaks through the ionosphere and reaches RAE with magnitudes 15 or more db higher than cosmic noise background. Maximum terrestrial noise is observed when RAE is over the dark side of the Earth in the neighborhood of equatorial continental land masses where thunderstorms occur most frequently. The observed noise level is 30-40 db lower with RAE over oceans.
Optical measurement of mouse strain differences in cerebral blood flow using indocyanine green
Kang, Hye-Min; Sohn, Inkyung; Kim, Seunggyu; Kim, Daehwan; Jung, Junyang; Jeong, Joo-Won; Park, Chan
2015-01-01
C57BL/6 mice have more cerebral arterial branches and collaterals than BALB/c mice. We measured and compared blood flow dynamics of the middle cerebral artery (MCA) in these two strains, using noninvasive optical imaging with indocyanine green (ICG). Relative maximum fluorescence intensity (Imax) and the time needed for ICG to reach Imax in the MCA of C57BL/c were lower than that in BALB/c mice. Moreover, the mean transit time was significantly lower in C57BL/6 than in BALB/c mice. These data suggest that the higher number of arterial branches and collaterals in C57BL/6 mice yields a lower blood flow per cerebral artery. PMID:25833343
Ye, Bo; Lu, Yaobin; Luo, Haiping; Liu, Guangli; Zhang, Renduo
2018-03-01
The aim of this study was to investigate the feasibility to improve the tetramethyl ammonium hydroxide (TMAH) production in the microbial electrolysis desalination and chemical-production cell (MEDCC) with long anode of 48 cm. Different concentrations of tetramethylammonium chloride (0.3-0.7 M) and applied voltages (1.5-3.5 V) were tested in the MEDCC. With 0.6 M of tetramethylammonium chloride as the raw material and under the applied voltage of 3.5 V, the maximum TMAH production rate in the MEDCC reached 1.13 ± 0.12 mmol/h, which was 9.4 times higher than those previously reported in the MEDCCs. The maximum current density of 41.0 ± 4.0 A/m 2 in the MEDCC was obtained, which was the highest value in the bioelectrochemical systems using the carbon cloth or carbon brush as the anode so far. Our results should provide a promising method to improve the TMAH production and boost the MEDCC application. Copyright © 2018 Elsevier Ltd. All rights reserved.
Accelerations and Passenger Harness Loads Measured in Full-Scale Light-Airplane Crashes
NASA Technical Reports Server (NTRS)
Eiband, A. Martin; Simpkinson, Scott H.; Black, Dugald O.
1953-01-01
Full-scale light-airplane crashes simulating stall-spin accidents were conducted to determine the decelerations to which occupants are exposed and the resulting harness forces encountered in this type of accident. Crashes at impact speeds from 42 to 60 miles per hour were studied. The airplanes used were of the familiar steel-tube, fabric-covered, tandem, two-seat type. In crashes up to an impact speed of 60 miles per hour, crumpling of the forward fuselage structure prevented the maximum deceleration at the rear-seat location from exceeding 26 to 33g. This maximum g value appeared independent of the impact speed. Restraining forces in the seatbelt - shoulder-harness combination reached 5800 pounds. The rear-seat occupant can survive crashes of the type studied at impact speeds up to 60 miles per hour, if body movement is restrained by an adequate seatbelt-shoulder-harness combination so as to prevent injurious contact with obstacles normally present in the cabin. Inwardly collapsing cabin structure, however, is a potential hazard in the higher-speed crashes.
NASA Astrophysics Data System (ADS)
Msaad, Asmaa; Belbahloul, Mounir; Zouhri, Abdeljalil
2018-05-01
Our activated carbon was prepared successfully using phosphoric acid as an activated agent. The activated carbon was characterized by Scanning Electron Micrograph (SEM), Brunauer-Emmett- Teller (BET), Fourier transform infrared spectroscopy (FT-IR) and X-ray diffraction (XRD). The aim of our study is to evaluate the adsorption capacity of Methyl Orange (MO) on Ziziphus lotus activated carbon. Adsorption isotherms were studied according to Langmuir and Freundlich Model, and adsorption kinetics according to pseudo-first and second-order. Results show that the maximum adsorption was reached in the first 10min at ambient temperature with a yield of 96.31%. The Langmuir isotherm shows a correlation coefficient of 99.4 % higher than Freundlich model and the adsorption kinetic model follow a pseudo-second-order with a maximum adsorption capacity of 769.23 mg/g. FTIR and X-Ray spectroscopy indicate that our activated carbon has an amorphous structure with the presence of functional groups, where BET analysis revealed a high surface area of 553 mg/g, which facilitate the adsorption process
On the morphology of outbursts of accreting millisecond X-ray pulsar Aquila X-1
NASA Astrophysics Data System (ADS)
Güngör, C.; Ekşi, K. Y.; Göğüş, E.
2017-10-01
We present the X-ray light curves of the last two outbursts - 2014 & 2016 - of the well known accreting millisecond X-ray pulsar (AMXP) Aquila X-1 using the monitor of all sky X-ray image (MAXI) observations in the 2-20 keV band. After calibrating the MAXI count rates to the all-sky monitor (ASM) level, we report that the 2016 outburst is the most energetic event of Aql X-1, ever observed from this source. We show that 2016 outburst is a member of the long-high class according to the classification presented by Güngör et al. with ˜ 68 cnt/s maximum flux and ˜ 60 days duration time and the previous outburst, 2014, belongs to the short-low class with ˜ 25 cnt/s maximum flux and ˜ 30 days duration time. In order to understand differences between outbursts, we investigate the possible dependence of the peak intensity to the quiescent duration leading to the outburst and find that the outbursts following longer quiescent episodes tend to reach higher peak energetic.
Evolution of conducting states and the maximum dissipated power
NASA Astrophysics Data System (ADS)
Bezryadin, A.; Tinkham, M.
1998-03-01
Evolution of conducting states in adaptable systems below the percolation threshold is studied experimentally. The sample consists of a pair of metal electrodes immersed into a colloidal suspension of conducting graphite nanoparticles in an electrically insulating liquid (toluene, mineral oil). When this initially homogeneous system is driven far from equilibrium by biasing the electrodes with a high DC voltage, a breaking of translational symmetry occurs and the conductivity increases by many orders of magnitude. Two qualitatively different conducting states are observed. The first is a self-organized critical state characterized by a sequence of avalanches with a 1/f^α power spectrum. In the process of evolution this state may transform into the second, ordered stable state with higher conductivity. The transition into the stable state occurs only if the system reaches the point when the power dissipated in the suspension is the maximum allowed by the bias voltage and series resistor. The critical states decay within a few hours while the stable states, which are characterized by visible strings of particles connecting the electrodes, exist much longer.
NASA Astrophysics Data System (ADS)
Li, Huan; Tang, Xiaobin; Chen, Feida; Huang, Hai; Liu, Jian; Chen, Da
2016-07-01
The radiation damage and microstructure evolution of different zigzag single-walled carbon nanotubes (SWCNTs) were investigated under incident carbon ion by molecular dynamics (MD) simulations. The radiation damage of SWCNTs under incident carbon ion with energy ranging from 25 eV to 1 keV at 300 K showed many differences at different incident sites, and the defect production increased to the maximum value with the increase in incident ion energy, and slightly decreased but stayed fairly stable within the majority of the energy range. The maximum damage of SWCNTs appeared when the incident ion energy reached 200 eV and the level of damage was directly proportional to incident ion fluence. The radiation damage was also studied at 100 K and 700 K and the defect production decreased distinctly with rising temperature because radiation-induced defects would anneal and recombine by saturating dangling bonds and reconstructing carbon network at the higher temperature. Furthermore, the stability of a large-diameter tube surpassed that of a thin one under the same radiation environments.
Abundance of adult saugers across the Wind River watershed, Wyoming
Amadio, C.J.; Hubert, W.A.; Johnson, K.; Oberlie, D.; Dufek, D.
2006-01-01
The abundance of adult saugers Sander canadensis was estimated over 179 km of continuous lotic habitat across a watershed on the western periphery of their natural distribution in Wyoming. Three-pass depletions with raft-mounted electrofishing gear were conducted in 283 pools and runs among 19 representative reaches totaling 51 km during the late summer and fall of 2002. From 2 to 239 saugers were estimated to occur among the 19 reaches of 1.6-3.8 km in length. The estimates were extrapolated to a total population estimate (mean ?? 95% confidence interval) of 4,115 ?? 308 adult saugers over 179 km of lotie habitat. Substantial variation in mean density (range = 1.0-32.5 fish/ha) and mean biomass (range = 0.5-16.8 kg/ha) of adult saugers in pools and runs was observed among the study reaches. Mean density and biomass were highest in river reaches with pools and runs that had maximum depths of more than 1 m, mean daily summer water temperatures exceeding 20??C, and alkalinity exceeding 130 mg/L. No saugers were captured in the 39 pools or runs with maximum water depths of 0.6 m or less. Multiple-regression analysis and the information-theoretic approach were used to identify watershed-scale and instream habitat features accounting for the variation in biomass among the 244 pools and runs across the watershed with maximum depths greater than 0.6 m. Sauger biomass was greater in pools than in runs and increased as mean daily summer water temperature, maximum depth, and mean summer alkalinity increased and as dominant substrate size decreased. This study provides an estimate of adult sauger abundance and identifies habitat features associated with variation in their density and biomass across a watershed, factors important to the management of both populations and habitat. ?? Copyright by the American Fisheries Society 2006.
Mericske-Stern, R
1998-01-01
The purpose of this in vivo study was to determine maximum and functional forces simultaneously in three dimensions on mandibular implants supporting overdentures. The anchorage system for overdenture connection was the ball-shaped retentive anchor. Five edentulous patients, each with two mandibular ITI implants, were selected as test subjects. A novel miniaturized piezo-electric force transducer was developed for specific use with ITI implants. Force magnitudes and directions were registered under various test conditions by means of electrostatic plotter records. The test modalities were maximum biting in centric occlusion, maximum biting on a bite plate, grinding, and chewing bread. Maximum forces measured in centric occlusion and on the ipsilateral implant when using a bite plate were slightly increased in vertical and backward-forward dimension (z-, y-axis) compared to the lateral-medial direction (x-axis). On the contralateral implant, equally low values were found in all three dimensions. This may be the effect of a nonsplinted anchorage device. With the use of a bite plate, force magnitudes on the ipsilateral implant were significantly higher on the z- and y-axis than mean maximum forces in centric occlusion (P < .001). Chewing and grinding resulted in lower forces compared to maximum biting, particularly in the vertical direction. The transverse force component in backward-forward direction, however, reached magnitudes that exceeded the vertical component by 100% to 300% during chewing function. This chewing pattern had not been observed in previous investigations with bars and telescopes, and therefore appears to be specific for retentive ball anchors. The prevalent or exclusive force direction registered on both implants in the vertical direction was downward under all test conditions. In the transverse direction during maximum biting the forward direction was more frequently registered, while no obvious prevalence of transverse force direction was observed during chewing and grinding.
Equatorial temperature anomaly during solar minimum
NASA Astrophysics Data System (ADS)
Suhasini, R.; Raghavarao, R.; Mayr, H. G.; Hoegy, W. R.; Wharton, L. E.
2001-11-01
We show evidence for the occurrence of the equatorial temperature anomaly (ETA) during solar minimum by analyzing the temperature and total ion density data from the Neutral Atmosphere Temperature Experiment (NATE) and the Cylindrical Electrostatic Probe (CEP), respectively, on board the Atmospheric Explorer-E satellite. The chosen data refer to a height of ~254 km in the African and Asian longitude sector (340.1°E-200°E) during a summer season in the Southern Hemisphere. As during the solar maximum period, the spatial characteristics of the ETA are similar to those of the equatorial ionization anomaly (EIA). A minimum in the gas temperature is collocated with the minimum in the ion density at the dip equator, and a temperature maximum on the south side of the equator is collocated with the density maximum of the EIA. The daytime behavior of ETA formation is about the same as that of EIA as both of them are clearly present at around 1300 and 1400 local solar time (LST) only. At 1400 LST the difference between the temperatures at the crest and the trough (ETA strength) reaches a maximum value of about 100°K which is ~14% of the temperature at the trough. Like the EIA, the ETA also suddenly disappears after 1400 LST. Thus the EIA appears to be a prerequisite for the ETA formation. During the premidnight time (2200 LST), however, while the EIA is nonexistent, the temperature distribution forms a pattern opposite to that at 1400 LST in the daytime. It shows a maximum around the dip equator and a broad minimum at the daytime crest region where the postsunset cooling also is faster and occurs earlier than at the dip equator. This nighttime maximum appears to be related to the signature of the midnight temperature maximum (MTM). Mass Spectrometer Incoherent Scatter (MSIS) model temperatures, in general, are higher than the observed average temperatures for the summer season and in particular for the region around the dip equator around noon hours.
DELIVERY OF DUST GRAINS FROM COMET C/2013 A1 (SIDING SPRING) TO MARS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tricarico, Pasquale; Samarasinha, Nalin H.; Sykes, Mark V.
Comet C/2013 A1 (Siding Spring) will have a close encounter with Mars on 2014 October 19. We model the dynamical evolution of dust grains from the time of their ejection from the comet nucleus to the close encounter with Mars, and determine the flux at Mars. Constraints on the ejection velocity from Hubble Space Telescope observations indicate that the bulk of the grains will likely miss Mars, although it is possible that a few percent of the grains with higher velocities will reach Mars, peaking approximately 90-100 minutes after the close approach of the nucleus, and consisting mostly of millimeter-radiusmore » grains ejected from the comet nucleus at a heliocentric distance of approximately 9 AU or larger. At higher velocities, younger grains from submillimeter to several millimeters can also reach Mars, although an even smaller fraction of grains is expected have these velocities, with negligible effect on the peak timing. Using NEOWISE observations of the comet, we can estimate that the maximum fluence will be of the order of 10{sup –7} grains m{sup –2}. We include a detailed analysis of how the expected fluence depends on the grain density, ejection velocity, and size-frequency distribution, to account for current model uncertainties and in preparation of possible refined model values in the near future.« less
Strategies of leaf expansion in Ficus carica under semiarid conditions.
González-Rodríguez, A M; Peters, J
2010-05-01
Leaf area expansion, thickness and inclination, gas exchange parameters and relative chlorophyll content were analysed in field-grown fig (Ficus carica L.) leaves over time, from emergence until after full leaf expansion (FLE). Ficus carica leaves showed a subtle change in shape during the early stages of development, and FLE was reached within ca. 30 days after emergence. Changes in leaf thickness and inclination after FLE demonstrated good adaptation to environmental conditions during summer in areas with a Mediterranean climate. Changes in gas exchange parameters and relative chlorophyll content showed that F. carica is a delayed-greening species, reaching maximum values 20 days after FLE. Correlation analysis of datasets collected during leaf expansion, confirmed dependence among structural and functional traits in F. carica. Pn was directly correlated with stomatal conductance (Gs), transpiration (E), leaf area (LA) and relative chlorophyll content up to FLE. The effect of pruning on leaf expansion, a cultural technique commonly applied in this fruit tree, was also evaluated. Although leaf development in pruned branches gave a significantly higher relative leaf area growth rate (RGR(l)) and higher LA than non-pruned branches, no significant differences were found in other morphological and physiological traits, indicating no pruning effect on leaf development. All studied morphological and physiological characteristics indicate that F. carica is well adapted to semiarid conditions. The delayed greening strategy of this species is discussed.
Reach-scale effects of riparian forest cover on urban stream ecosystems
Roy, A.H.; Faust, C.L.; Freeman, Mary C.; Meyer, J.L.
2005-01-01
We compared habitat and biota between paired open and forested reaches within five small streams (basin area 10?20 km2) in suburban catchments (9%?49% urban land cover) in the Piedmont of Georgia, USA. Stream reaches with open canopies were narrower than forested reaches (4.1 versus 5.0 m, respectively). There were no differences in habitat diversity (variation in velocity, depth, or bed particle size) between open and forested reaches. However, absence of local forest cover corresponded to decreased large wood and increased algal chlorophyll a standing crop biomass. These differences in basal food resources translated into higher densities of fishes in open (9.0 individuals?m?2) versus forested (4.9 individuals?m?2) reaches, primarily attributed to higher densities of the herbivore Campostoma oligolepis. Densities of terrestrial invertebrate inputs were higher in open reaches; however, trends suggested higher biomass of terrestrial inputs in forested reaches and a corresponding higher density of terrestrial prey consumed by water column feeding fishes. Reach-scale biotic integrity (macroinvertebrates, salamanders, and fishes) was largely unaffected by differences in canopy cover. In urbanizing areas where catchment land cover drives habitat and biotic quality, management practices that rely exclusively on forested riparian areas for stream protection are unlikely to be effective at maintaining ecosystem integrity.
Bekircan, Tuba; Yaşar, Ahmet; Yıldırım, Sercan; Sökmen, Münevver; Sökmen, Atalay
2018-03-01
An efficient in vitro multiplication protocol was designed to Thymus leucotrichus , a subshrub and perennial herb growing naturally in the Northwest of Turkey. Of all basal media studied, Murashige and Skoog medium was found to be superior to the others, providing higher shoot formation and the maximum shoot length. Varying concentrations of cytokinins, i.e., 6-benzyladenine, thidiazuron, 2-isopentenyladenine and kinetin were supplemented in the nutrient media to observe their effects on shoot development and biomass. Rosmarinic acid content and volatile compositions of both naturally growing plants and in vitro multiplied plantlets were also evaluated. 6-benzyladenine (1.0 mg/L) and kinetin (0.5 mg/L) were found to be optimum for shoot number and shoot elongation, respectively. Thidiazuron (1.0 mg/L) was superior for biomass production. Rosmarinic acid content of in vitro multiplied plants was found to be higher than that of wild plants, reaching a maximum with 0.5 mg/L 2-isopentenyladenine, which yielded 10.15 mg/g dry weight. The highest thymol content was obtained with 1.0 mg/L kinetin (55.82%), while thidiazuron (0.1 mg/L) increased carvacrol production (12.53%). Overall, Murashige and Skoog medium supplemented with 1.0 mg/L kinetin was determined to be the most favorable medium studied.
Levofloxacin pharmacokinetics in adult cystic fibrosis.
Lee, Carlton K K; Boyle, Michael P; Diener-West, Marie; Brass-Ernst, Lois; Noschese, Michelle; Zeitlin, Pamela L
2007-03-01
Cystic fibrosis (CF) patients have enhanced renal clearance of aminoglycosides and several beta-lactams and require higher dosages. Levofloxacin is a fluoroquinolone with extensive renal elimination and enhanced penetration into lungs and Pseudomonas aeruginosa (PA) biofilms. We studied the preliminary pharmacokinetic and pharmacodynamic (PK/PD) relationship of levofloxacin in CF. Twelve patients at least 18 years old with a mild-to-moderate pulmonary exacerbation and fluoroquinolone-sensitive PA colonization received oral levofloxacin, 500 mg qd, for 14 days. Steady-state serum concentrations were collected after 3 to 7 days, and sputum samples for PA densities were collected before and after levofloxacin. PK/PD relationships for reducing PA sputum densities were evaluated. When compared to published data on non-CF patients, CF patients had similar area under the curve for 24 h (AUC(24)), total clearance, volume of distribution, maximum serum concentration (Cpmax), and elimination half-life: mean, 7.33 microg x h/mL/kg (SD, 1.70); 2.43 mL/min/kg (SD, 0.74); 1.33 L/kg (SD, 0.37); 7.06 microg/mL (SD, 2.35); and 6.44 h (SD, 1.1), respectively. Time to reach maximum serum concentration (Tmax) in CF was longer: mean, 2.20 h (SD, 0.99) vs 1.1 h (SD, 0.4) [p < 0.01]. Preliminary PK/PD analysis failed to demonstrate trends for decreasing PA sputum densities with increasing Cpmax/minimum inhibitory concentration (MIC) ratio and AUC(24)/MIC ratio. CF levofloxacin pharmacokinetics corrected for body weight are similar to non-CF, except for Tmax. Standard levofloxacin dosing (especially monotherapy) is unlikely to produce maximum therapeutic effectiveness. Additional levofloxacin studies in CF are necessary to evaluate its sputum concentrations; the benefits of higher daily dosages (>/= 750 mg); and establish PK/PD targets for managing PA pulmonary infections.
Studies on the positive inotropic effect of phenylephrine: a comparison with isoprenaline.
Ledda, F; Marchetti, P; Mugelli, A
1975-05-01
1. The effects of phenylephrine and isoprenaline on the isometric contraction of guinea-pig ventricle were compared over the whole range of their respective dose-response curves. 2. In preparations driven at 2.5 Hz the increase in contractile force induced by either isoprenaline of phenylephrine was linearly correlated to an increase in maximum velocity of force development. The relaxation time was shortened by isoprenaline but not by phenylephrine. 3. The negative inotropic effect induced by delta [N-(3,4-dimethoxyphenethyl)-N-methyl-amino]-alpha-(3,4,5-trimethoxyphenyl)alpha-isopropylvaleronitrile hydrochloride (D(600)) was reversed by isoprenaline, but little influenced by phenylephrine. 4. The study of the interval-force relationship shows that the increase in contractile force induced by phenylephrine (3 X 10(-5) M) was relatively greater at low frequencies of stimulation, and that the maximum effect was reached at the frequency of 1 Hz. 5. The positive inotropic effect of phenylephrine (10-4 M) was significantly higher at a frequency of 1 Hz than at 2.5 Hz; the effect of isoprenaline (3 x 10-8 M) was not significantly different at the two driving frequencies. 6. In preparations driven at 1 Hz the inotropic effect of the lower concentrations of phenylephrine was due to an increase in the time to peak tension without any change of the maximum velocity of force development; however an increase of this parameter became evident only after higher concentrations of the amine (10-5 M or more), associated with a progressive shortening of the time to peak. 7. A correlation between mechanical and electrophysiological effects of phenylephrine is attempted; the suggestion is advanced that the prolongation of the action potential and of the active state duration may be an important factor in the inotropic effect of phenylephrine.
NASA Astrophysics Data System (ADS)
Brosse, Fabien; Leriche, Maud; Mari, Céline; Couvreux, Fleur
2018-05-01
The hydroxyl radical (OH) is a highly reactive species and plays a key role in the oxidative capacity of the atmosphere. We explore the potential impact of a convective boundary layer on reconciling the calculation-measurement differences for OH reactivity (the inverse of OH lifetime) attributable to the segregation of OH and its reactants by thermals and the resulting modification of averaged reaction rates. The large-eddy simulation version of the Meso-NH model is used, coupled on-line with a detailed chemistry mechanism to simulate two contrasted biogenic and urban chemical regimes. In both environments, the top of the boundary layer is the region with the highest calculated segregation intensities but with the opposite sign. In the biogenic environment, the inhomogeneous mixing of isoprene and OH leads to a maximum decrease of 30 % of the mean reaction rate in this zone. In the anthropogenic case, the effective rate constant for OH reacting with aldehydes is 16 % higher than the averaged value. OH reactivity is always higher by 15 to 40 % inside thermals in comparison to their surroundings as a function of the chemical environment and time of the day. Since thermals occupy a small fraction of the simulated domain, the impact of turbulent motions on domain-averaged total OH reactivity reaches a maximum decrease of 9 % for the biogenic case and a maximum increase of 5 % for the anthropogenic case. Accounting for the segregation of air masses by turbulent motions in regional and global models may increase OH reactivity in urban environments but lower OH reactivity in biogenic environments. In both cases, segregation alone is insufficient for resolving the underestimation between observed and modeled OH reactivity.
A case of rapid rock riverbed incision in a coseismic uplift reach and its implications
NASA Astrophysics Data System (ADS)
Huang, Ming-Wan; Pan, Yii-Wen; Liao, Jyh-Jong
2013-02-01
During the 1999 Chi-Chi earthquake (Mw = 7.6) in Taiwan, the coseismic displacement induced fault scarps and a pop-up structure in the Taan River. The fault scarps across the river experienced maximum vertical slip of 10 m, which disturbed the dynamic equilibrium of the fluvial system. As a result, rapid incision in the weak bedrock, with a maximum depth of 20 m, was activated within a decade after its armor layer was removed. This case provides an excellent opportunity for closely tracking and recording the progressive evolution of river morphology that is subjected to coseismic uplift. Based on multistaged orthophotographs and digital elevation model (DEM) data, the process of morphology evolution in the uplift reach was divided into four consecutive stages. Plucking is the dominant mechanism of bedrock erosion associated with channel incision and knickpoint migration. The astonishingly high rate of knickpoint retreat (KPR), as rapid as a few hundred meters per year, may be responsible for the rapid incision in the main channel. The reasons for the high rate of KPR are discussed in depth. The total length of the river affected by the coseismic uplift is 5 km: 1 km in the uplift reach and 4 km in the downstream reach. The downstream reach was affected by a reduction in sediment supply and increase in stream power. The KPR cut through the uplift reach within roughly a decade; further significant flooding in the future will mainly cause widening instead of deepening of the channel.
Kinetics of the head-neck complex in low-speed rear impact.
Stemper, Brian D; Yoganandan, Naryan; Pintar, Frank A
2003-01-01
A comprehensive characterization of the biomechanics of the cervical spine in rear impact will lead to an understanding of the mechanisms of whiplash injury. Cervical kinematics have been experimentally described using human volunteers, full-body cadaver specimens, and isolated and intact head-neck specimens. However, forces and moments at the cervico-thoracic junction have not been clearly delineated. An experimental investigation was performed using ten intact head-neck complexes to delineate the loading at the base of the cervical spine and angular acceleration of the head in whiplash. A pendulum-minisled apparatus was used to simulate whiplash acceleration of the thorax at four impact severities. Lower neck loads were measured using a six-axis load cell attached between the minisled and head-neck specimens, and head angular motion was measured with an angular rate sensor attached to the lateral side of the head. Shear and axial force, extension moment, and head angular acceleration increased with impact severity. Shear force was significantly larger than axial force (p < 0.0001). Shear force reached its maximum value at 46 msec. Maximum extension moment occurred between 7 and 22 msec after maximum shear force. Maximum angular acceleration of the head occurred 2 to 18 msec later. Maximum axial force occurred last (106 msec). All four kinetic components reached maximum values during cervical S-curvature, with maximum shear force and extension moment occurring before the attainment of maximum S-curvature. Results of the present investigation indicate that shear force and extension moment at the cervico-thoracic junction drive the non-physiologic cervical S-curvature responsible for whiplash injury and underscore the importance of understanding cervical kinematics and the underlying kinetics.
Dedola, Fabrizio; Cabizza, Maddalena; Satta, Maurizio
2014-01-01
The behavior of 28 pesticides on two tomato cultivars with a different surface/weight (S/W) ratio of the berries (S/W, Birikino vs. Tombola) was studied, in order to provide appropriate indications about their persistence on crops reaching the pre-harvest interval (PHI). Quantitative analysis was performed using a GC MS/MS method. Birikino cv. (BIR) was a "cherry type tomato" with a double S/W ratio compared with Tombola cv. (TOM). The results showed a different pesticide behavior. Azoxystrobin, Boscalid, Bupirimate, Difenoconazole, Etofenprox, Iprodione, Mepanipyrim, Myclobutanil, Tebuconazole, Zoxamide, Metalaxyl M, Pyrimethanil, Tetraconazole, Benalaxyl, Cyprodinil, Fenamidone, Famoxadone and Fludioxonil immediately after treatments showed residues on BIR higher than TOM, and this behavior is consistent with its greater exposed surface. BIR showed higher decay rates of these pesticides during the whole trial, nevertheless residue averages remained higher than TOM reaching the time of harvest. Residues at the PHI were all below their Maximum Residue Levels (MRLs), but data indicated that they could exceed their legal limits especially if the above-mentioned active ingredients were employed more than once per crop cycle on cherry type tomatoes. As regards to Chlorpyrifos, Chlorpyrifos methyl, Triadimenol, Pyridaben and Tebufenpyrad, no different residual behavior related to S/W ratio of the cultivars was observed. Even in this case, residues at the PHI were all below MRLs. As for Cyfluthrin, Deltamethrin, Lambda cyhalothrin, Etoxazole and Cyproconazole, residues were lower than the limit of quantitation (LOQ) of the analytical method just after the treatment, according to their low doses of employment.
Galbany, Jordi; Abavandimwe, Didier; Vakiener, Meagan; Eckardt, Winnie; Mudakikwa, Antoine; Ndagijimana, Felix; Stoinski, Tara S; McFarlin, Shannon C
2017-07-01
Great apes show considerable diversity in socioecology and life history, but knowledge of their physical growth in natural settings is scarce. We characterized linear body size growth in wild mountain gorillas from Volcanoes National Park, Rwanda, a population distinguished by its extreme folivory and accelerated life histories. In 131 individuals (0.09-35.26 years), we used non-invasive parallel laser photogrammetry to measure body length, back width, arm length and two head dimensions. Nonparametric LOESS regression was used to characterize cross-sectional distance and velocity growth curves for males and females, and consider links with key life history milestones. Sex differences became evident between 8.5 and 10.0 years of age. Thereafter, female growth velocities declined, while males showed increased growth velocities until 10.0-14.5 years across dimensions. Body dimensions varied in growth; females and males reached 98% of maximum body length at 11.7 and 13.1 years, respectively. Females attained 95.3% of maximum body length by mean age at first birth. Neonates were 31% of maternal size, and doubled in size by mean weaning age. Males reached maximum body and arm length and back width before emigration, but experienced continued growth in head dimensions. While comparable data are scarce, our findings provide preliminary support for the prediction that mountain gorillas reach maximum body size at earlier ages compared to more frugivorous western gorillas. Data from other wild populations are needed to better understand comparative great ape development, and investigate links between trajectories of physical, behavioral, and reproductive maturation. © 2017 Wiley Periodicals, Inc.
Pressure, stress, and strain distribution in the double-stage diamond anvil cell
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lobanov, Sergey S., E-mail: slobanov@carnegiescience.edu; V.S. Sobolev Institute of Geology and Mineralogy SB RAS, Novosibirsk 630090; Prakapenka, Vitali B.
Double stage diamond anvil cells (DACs) of two designs have been assembled and tested. We used a standard symmetric DAC with flat or beveled culets as a primary stage and CVD microanvils machined by a focused ion beam as a second. We evaluated pressure, stress, and strain distributions in gold and a mixture of gold and iron as well as in secondary anvils using synchrotron x-ray diffraction with a micro-focused beam. A maximum pressure of 240 GPa was reached independent of the first stage anvil culet size. We found that the stress field generated by the second stage anvils is typicalmore » of conventional DAC experiments. The maximum pressures reached are limited by strains developing in the secondary anvil and by cupping of the first stage diamond anvil in the presented experimental designs. Also, our experiments show that pressures of several megabars may be reached without sacrificing the first stage diamond anvils.« less
Larsen, C R; Grantcharov, T; Aggarwal, R; Tully, A; Sørensen, J L; Dalsgaard, T; Ottesen, B
2006-09-01
Safe realistic training and unbiased quantitative assessment of technical skills are required for laparoscopy. Virtual reality (VR) simulators may be useful tools for training and assessing basic and advanced surgical skills and procedures. This study aimed to investigate the construct validity of the LapSimGyn VR simulator, and to determine the learning curves of gynecologists with different levels of experience. For this study, 32 gynecologic trainees and consultants (juniors or seniors) were allocated into three groups: novices (0 advanced laparoscopic procedures), intermediate level (>20 and <60 procedures), and experts (>100 procedures). All performed 10 sets of simulations consisting of three basic skill tasks and an ectopic pregnancy program. The simulations were carried out on 3 days within a maximum period of 2 weeks. Assessment of skills was based on time, economy of movement, and error parameters measured by the simulator. The data showed that expert gynecologists performed significantly and consistently better than intermediate and novice gynecologists. The learning curves differed significantly between the groups, showing that experts start at a higher level and more rapidly reach the plateau of their learning curve than do intermediate and novice groups of surgeons. The LapSimGyn VR simulator package demonstrates construct validity on both the basic skills module and the procedural gynecologic module for ectopic pregnancy. Learning curves can be obtained, but to reach the maximum performance for the more complex tasks, 10 repetitions do not seem sufficient at the given task level and settings. LapSimGyn also seems to be flexible and widely accepted by the users.
A Water Temperature Simulation Model for Rice Paddies With Variable Water Depths
NASA Astrophysics Data System (ADS)
Maruyama, Atsushi; Nemoto, Manabu; Hamasaki, Takahiro; Ishida, Sachinobu; Kuwagata, Tsuneo
2017-12-01
A water temperature simulation model was developed to estimate the effects of water management on the thermal environment in rice paddies. The model was based on two energy balance equations: for the ground and for the vegetation, and considered the water layer and changes in the aerodynamic properties of its surface with water depth. The model was examined with field experiments for water depths of 0 mm (drained conditions) and 100 mm (flooded condition) at two locations. Daily mean water temperatures in the flooded condition were mostly higher than in the drained condition in both locations, and the maximum difference reached 2.6°C. This difference was mainly caused by the difference in surface roughness of the ground. Heat exchange by free convection played an important role in determining water temperature. From the model simulation, the temperature difference between drained and flooded conditions was more apparent under low air temperature and small leaf area index conditions; the maximum difference reached 3°C. Most of this difference occurred when the range of water depth was lower than 50 mm. The season-long variation in modeled water temperature showed good agreement with an observation data set from rice paddies with various rice-growing seasons, for a diverse range of water depths (root mean square error of 0.8-1.0°C). The proposed model can estimate water temperature for a given water depth, irrigation, and drainage conditions, which will improve our understanding of the effect of water management on plant growth and greenhouse gas emissions through the thermal environment of rice paddies.
Coil optimisation for transcranial magnetic stimulation in realistic head geometry.
Koponen, Lari M; Nieminen, Jaakko O; Mutanen, Tuomas P; Stenroos, Matti; Ilmoniemi, Risto J
Transcranial magnetic stimulation (TMS) allows focal, non-invasive stimulation of the cortex. A TMS pulse is inherently weakly coupled to the cortex; thus, magnetic stimulation requires both high current and high voltage to reach sufficient intensity. These requirements limit, for example, the maximum repetition rate and the maximum number of consecutive pulses with the same coil due to the rise of its temperature. To develop methods to optimise, design, and manufacture energy-efficient TMS coils in realistic head geometry with an arbitrary overall coil shape. We derive a semi-analytical integration scheme for computing the magnetic field energy of an arbitrary surface current distribution, compute the electric field induced by this distribution with a boundary element method, and optimise a TMS coil for focal stimulation. Additionally, we introduce a method for manufacturing such a coil by using Litz wire and a coil former machined from polyvinyl chloride. We designed, manufactured, and validated an optimised TMS coil and applied it to brain stimulation. Our simulations indicate that this coil requires less than half the power of a commercial figure-of-eight coil, with a 41% reduction due to the optimised winding geometry and a partial contribution due to our thinner coil former and reduced conductor height. With the optimised coil, the resting motor threshold of abductor pollicis brevis was reached with the capacitor voltage below 600 V and peak current below 3000 A. The described method allows designing practical TMS coils that have considerably higher efficiency than conventional figure-of-eight coils. Copyright © 2017 Elsevier Inc. All rights reserved.
NASA Technical Reports Server (NTRS)
Karna, N.; Webber, S.A. Hess; Pesnell, W.D.
2014-01-01
An analysis of solar polar coronal hole (PCH) areas since the launch of the Solar Dynamics Observatory (SDO) shows how the polar regions have evolved during Solar Cycle 24. We present PCH areas from mid-2010 through 2013 using data from the Atmospheric Imager Assembly (AIA) and Helioseismic and Magnetic Imager (HMI) instruments onboard SDO. Our analysis shows that both the northern and southern PCH areas have decreased significantly in size since 2010. Linear fits to the areas derived from the magnetic-field properties indicate that, although the northern hemisphere went through polar-field reversal and reached solar-maximum conditions in mid-2012, the southern hemisphere had not reached solar-maximum conditions in the polar regions by the end of 2013. Our results show that solar-maximum conditions in each hemisphere, as measured by the area of the polar coronal holes and polar magnetic field, will be offset in time.
Gan, Tao; Zhang, Yanjuan; Chen, Yane; Hu, Huayu; Yang, Mei; Huang, Zuqiang; Chen, Dong; Huang, Aimin
2018-02-01
Three main components of lignocellulose (cellulose, hemicellulose, and lignin isolated from sugarcane bagasse (SCB)) as well as holocellulose and SCB were modified with maleic acid by mechanical activation (MA)-assisted solid phase reaction (MASPR) technology. The order of reactivity was found to be lignin>hemicellulose>cellulose. The amorphous structure of lignin and hemicellulose mainly attributed to their better reactivity, and the modified lignin could reach a maximum degree of esterification (DE) of 93.45%. MA improved the accessibility and reactivity of cellulose, as the DE of modified cellulose gradually increased with milling time and reached the maximum value of 57.30% at 120min, which had significant effect on structure changes and DE of modified holocellulose and SCB. MA enhanced the esterification of all three components in lignocellulose with relatively high substituent distribution in them, and maleated SCB with a maximum DE of 64.17% was successfully prepared by this simple, green, and effective MASPR technology. Copyright © 2017 Elsevier Ltd. All rights reserved.
Structural properties of H-implanted InP crystals
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bocchi, C.; Franzosi, P.; Lazzarini, L.
1993-07-01
H has been implanted in InP crystals at the energy E [equals] 100 keV and at different doses ranging from [sigma] [equals] 1 x 10[sup 13] to [sigma] [equals] 5 x 10[sup 16] cm[sup [minus]2]. The depth dependence of the elastic lattice strain has been investigated by high resolution X-ray diffractometry. The implantation produces a lattice dilation. The strain increases with increasing depth, reaches the maximum at about 0.75 [mu]m, and then decreases rapidly; moreover the maximum strain is proportional to the dose. No extended crystal defects have been detected by transmission electron microscopy up to [sigma] <1 x 10[supmore » 16] cm[sup [minus]2] a buried amorphous layer 28 nm in thickness has been observed at the same depth where the strain is maximum. The thickness of the amorphous layer increases by further increasing the dose and reaches a value of about 0.18 [mu]m for [sigma] [equals] 5 x 10[sup 16] cm[sup [minus]2].« less
Majoros, Attila; Bach, Dietmar; Keszthelyi, Attila; Hamvas, Antal; Romics, Imre
2006-01-01
During this prospective study we analyzed the effects of radical retropubic prostatectomy (RRP) on bladder and sphincter function by comparing preoperative and postoperative urodynamic data. The aim of the study was to determine the reason for urinary incontinence after RRP and explain why one group of patients will be immediately continent after catheter removal, while others need some time to reach complete continence. Urodynamic examination was performed in 63 patients 3-7 days before and 2 months after surgery. Forty-three (68.2%) and 53 (84.1%) patients regained continence at 2 and 9 months following RRP, respectively. Ten patients (15.9%) were immediately continent after catheter removal. Urodynamic stress incontinence was detected in 18 (28.6%), and detrusor overactivity incontinence in 2 (3.2%) patients 2 months after surgery. The amplitude of preoperative maximal voluntary sphincteric contractions was significantly higher in the postoperative continent group (125 vs. 96.5 cmH(2)O, P < 0.0001). The patients who were immediately continent following catheter removal had no lower urinary tract symptoms (LUTS) and urodynamic abnormality preoperatively, and they had significantly higher preoperative and postoperative maximum urethral closure pressure (at rest and during voluntary sphincter contraction) than those who became continent later on. These data suggest that the main cause of incontinence after RRP is sphincteric weakness. In the continent group, those who became immediately continent had significantly higher maximum urethral closure pressure values at rest and at voluntary sphincteric contraction even before the surgery. Neurourol. Urodynam. (c) 2005 Wiley-Liss, Inc.
Quantitative regulation of B cell division destiny by signal strength.
Turner, Marian L; Hawkins, Edwin D; Hodgkin, Philip D
2008-07-01
Differentiation to Ab secreting and isotype-switched effector cells is tightly linked to cell division and therefore the degree of proliferation strongly influences the nature of the immune response. The maximum number of divisions reached, termed the population division destiny, is stochastically distributed in the population and is an important parameter in the quantitative outcome of lymphocyte responses. In this study, we further assessed the variables that regulate B cell division destiny in vitro in response to T cell- and TLR-dependent stimuli. Both the concentration and duration of stimulation were able to regulate the average maximum number of divisions undergone for each stimulus. Notably, a maximum division destiny was reached during provision of repeated saturating stimulation, revealing that an intrinsic limit to proliferation exists even under these conditions. This limit was linked directly to division number rather than time of exposure to stimulation and operated independently of the survival regulation of the cells. These results demonstrate that a B cell population's division destiny is regulable by the stimulatory conditions up to an inherent maximum value. Division destiny is a crucial parameter in regulating the extent of B cell responses and thereby also the nature of the immune response mounted.
How long do centenarians survive? Life expectancy and maximum lifespan.
Modig, K; Andersson, T; Vaupel, J; Rau, R; Ahlbom, A
2017-08-01
The purpose of this study was to explore the pattern of mortality above the age of 100 years. In particular, we aimed to examine whether Scandinavian data support the theory that mortality reaches a plateau at particularly old ages. Whether the maximum length of life increases with time was also investigated. The analyses were based on individual level data on all Swedish and Danish centenarians born from 1870 to 1901; in total 3006 men and 10 963 women were included. Birth cohort-specific probabilities of dying were calculated. Exact ages were used for calculations of maximum length of life. Whether maximum age changed over time was analysed taking into account increases in cohort size. The results confirm that there has not been any improvement in mortality amongst centenarians in the past 30 years and that the current rise in life expectancy is driven by reductions in mortality below the age of 100 years. The death risks seem to reach a plateau of around 50% at the age 103 years for men and 107 years for women. Despite the rising life expectancy, the maximum age does not appear to increase, in particular after accounting for the increasing number of individuals of advanced age. Mortality amongst centenarians is not changing despite improvements at younger ages. An extension of the maximum lifespan and a sizeable extension of life expectancy both require reductions in mortality above the age of 100 years. © 2017 The Association for the Publication of the Journal of Internal Medicine.
Resistivity of a simple metal from room temperature to 10 to the 6th K
NASA Astrophysics Data System (ADS)
Milchberg, H. M.; Freeman, R. R.; Davey, S. C.; More, R. M.
1988-11-01
The resistivity of nearly solid-density Al was measured as a function of temperature over 4 orders of magnitude above ambient by observing the self-reflection of an intense, less than 0.5 psec, 308-nm light pulse incident on a planar Al target. As an increasing function of electron temperature, the resistivity is observed initially to increase, reach a maximum which is relatively constant over an extended temperature range, and then decrease at the highest temperatures. The broad maximum is interpreted as resistivity saturation, a condition in which the mean free path of the conduction electrons reaches a minimum value as a function of temperature, regardless of the extent of any further disorder in the material.
A new structure of superconducting magnetic system for 50 GHz operations (invited).
Xie, D Z
2012-02-01
High field and high frequency have been leading the development of electron cyclotron resonance ion sources (ECRISs) in the past decade as demonstrated by the achieved great performance. The present superconducting magnet structures built with NbTi wires have reached an axial field of 3.5-4.0 T and a radial field of 2.0 T for operating frequency up to 28 GHz. Further increase of the magnetic field strength will require higher current superconductor, i.e., Nb(3)Sn wires. This paper will present the features of a new superconducting magnet structure and review of the existing structures. Using NbTi wires, the new magnet structure could be able to produce maximum fields of 7.0 T on axis and radial field of 3.7 T at a hexagonal plasma chamber wall for ECRIS operations up to 50 GHz. If this new magnet can be built with Nb(3)Sn wires, much higher fields can be expected.
Behaviors of Char Gasification Based on Two-stage Gasifier of Biomass
NASA Astrophysics Data System (ADS)
Taniguchi, Miki; Sasauchi, Kenichi; Ahn, Chulju; Ito, Yusuke; Hayashi, Toshiaki; Akamatsu, Fumiteru
In order to develop a small-scale gasifier in which biomass can be converted to energy with high efficiency, we planed a gasification process that consists of two parts: pyrolysis part (rotary kiln) and gasification part (downdraft gasifier). We performed fundamental experiments on gasification part and discussed the apropriate conditions such as air supply location, air ratio, air temperature and hearth load. The following results was found: 1) the air supply into the char bed is more effective than that into the gas phase, 2) we can have the maximum cold gas efficiency of 80% on the following conditions: air supply location: char layer, air temperature: 20°C, air ratio: 0.2. 3) As air temperature is higher, the cold gas efficiency is larger. As for the hearth load, the cold gas efficiency becomes higher and reaches the constant level. It is expected from the results that high temperature in the char layer is effective on the char gasification.
Nucleoprotein Changes in Plant Tumor Growth
Rasch, Ellen; Swift, Hewson; Klein, Richard M.
1959-01-01
Tumor cell transformation and growth were studied in a plant neoplasm, crown gall of bean, induced by Agrobacterium rubi. Ribose nucleic acid (RNA), deoxyribose nucleic acid (DNA), histone, and total protein were estimated by microphotometry of nuclei, nucleoli, and cytoplasm in stained tissue sections. Transformation of normal cells to tumor cells was accompanied by marked increases in ribonucleoprotein content of affected tissues, reaching a maximum 2 to 3 days after inoculation with virulent bacteria. Increased DNA levels were in part associated with increased mitotic frequency, but also with progressive accumulation of nuclei in the higher DNA classes, formed by repeated DNA doubling without intervening reduction by mitosis. Some normal nuclei of the higher DNA classes (with 2, 4, or 8 times the DNA content of diploid nuclei) were reduced to diploid levels by successive cell divisions without intervening DNA synthesis. The normal relation between DNA synthesis and mitosis was thus disrupted in tumor tissue. Nevertheless, clearly defined DNA classes, as found in homologous normal tissues, were maintained in the tumor at all times. PMID:13673042
Effect of a CoFeB layer on the anisotropic magnetoresistance of Ta/CoFeB/MgO/NiFe/MgO/CoFeB/Ta films
NASA Astrophysics Data System (ADS)
Li, Minghua; Shi, Hui; Dong, Yuegang; Ding, Lei; Han, Gang; Zhang, Yao; Liu, Ye; Yu, Guanghua
2017-10-01
The anisotropic magnetoresistance (AMR) and magnetic properties of NiFe films can be remarkably enhanced via CoFeB layer. In the case of an ultrathin NiFe film having a Ta/CoFeB/MgO/NiFe/MgO/CoFeB/Ta structure, the CoFeB/MgO layers suppressed the formation of magnetic dead layers and the interdiffusions and interface reactions between the NiFe and Ta layers. The AMR reached a maximum value of 3.56% at 450 °C. More importantly, a single NiFe (1 1 1) peak can be formed resulting in higher AMR values for films having CoFeB layer. This enhanced AMR also originated from the significant specular reflection of electrons owing to the crystalline MgO layer, together with the sharp interfaces with the NiFe layer. These factors together resulted in higher AMR and improved magnetic properties.
Bitome Essono, Paul Yannick; Dechaume-Moncharmont, François-Xavier; Mavoungou, Jacques; Obiang Mba, Régis; Duvallet, Gérard; Bretagnolle, François
2015-01-01
In order to minimize risks of pathogen transmission with the development of ecotourism in Gabon, a seasonal inventory has been performed in five contrasted biotopes in Ivindo (INP) and Moukalaba-Doudou (MDNP) National Parks. A total of 10,033 hematophagous flies were captured. The Glossinidae, with six different species identified, was the most abundant group and constitutes about 60% of the captured flies compared to the Stomoxys (6 species also identified) and Tabanidae with 28% and 12%, respectively. The Glossinidae showed a higher rate of capture in primary forest and in research camps. In INP, the Stomoxys showed a higher rate of capture in secondary forest and at village borders, whereas in MDNP the Stomoxys were captured more in the savannah area. Thus, each fly group seemed to reach maximum abundance in different habitats. The Glossinidae were more abundant in primary forest and near research camps while Stomoxys were more abundant in secondary forest and savannah. The Tabanidae did not show a clear habitat preference. PMID:26187781
Bioavailability of an R-α-Lipoic Acid/γ-Cyclodextrin Complex in Healthy Volunteers
Ikuta, Naoko; Okamoto, Hinako; Furune, Takahiro; Uekaji, Yukiko; Terao, Keiji; Uchida, Ryota; Iwamoto, Kosuke; Miyajima, Atsushi; Hirota, Takashi; Sakamoto, Norihiro
2016-01-01
R-α-lipoic acid (R-LA) is a cofactor of mitochondrial enzymes and a very strong antioxidant. R-LA is available as a functional food ingredient but is unstable against heat or acid. Stabilized R-LA was prepared through complexation with γ-cyclodextrin (CD), yielding R-LA/CD. R-LA/CD was orally administered to six healthy volunteers and showed higher plasma levels with an area under the plasma concentration-time curve that was 2.5 times higher than that after oral administration of non-complexed R-LA, although the time to reach the maximum plasma concentration and half-life did not differ. Furthermore, the plasma glucose level after a single oral administration of R-LA/CD or R-LA was not affected and no side effects were observed. These results indicate that R-LA/CD could be easily absorbed in the intestine. In conclusion, γ-CD complexation is a promising technology for delivering functional but unstable ingredients like R-LA. PMID:27314343
NASA Technical Reports Server (NTRS)
Rahmatullah, M.
1972-01-01
The grenade-TMA firing conducted in 1965-1967 bring out the following important features regarding the stratospheric circulation in the subtropics: (1) The temperature pattern during the month of March/April at Sonmiani is characterized by higher temperature than the corresponding CIRA 1965 value. (2) Double maxima in temperature has often been observed during spring. (3) In March the zonal wind is predominantly westerly reaching a maximum value of about 45 m/s at 55 km. (4) The meridional component exhibits oscillatory character between 45 and 60 kms. (5) The change from winter westerlies to summer easterlies first occurred around 50 km during April and gradually affected higher levels as the month progressed. (6) The height of the principal maxima at Sonmiani is located at 105 + or - 5 km. In autumn the wind at the principal maxima is below 100 m/s and is directed to NW, in spring it is of the order of 118 m/s but directed to E or NE.
Nitrogen and phosphorus removal from tertiary wastewater in an osmotic membrane photobioreactor.
Praveen, Prashant; Loh, Kai-Chee
2016-04-01
An osmotic membrane photobioreactor (OMPBR) was designed and operated for 162days for nitrogen and phosphorus removal from wastewater using Chlorella vulgaris. The removal efficiency for NH4(+)-N, NO3(-)-N and PO4(3-)-P reached as high as 95%, 53% and 89%, whereas the maximum removal rates were 3.41 mg/L-day, 0.20 mg/L-day and 0.8 mg/L-day, respectively. The microalgae exhibited high tendency to aggregate and attached to the bioreactor and membrane surfaces, and total biomass accumulation in the OMPBR was over 5 g/L. Salt accumulation and biofouling had adverse effects on membrane filtration, but the performance could be recovered through periodic backwashing of the membranes. Extracellular polymeric substances characterization indicated higher fraction of polysaccharides as compared to proteins. The biomass in the OMPBR accumulated higher levels of carbohydrates and chlorophyll. These results indicate the suitability of OMPBR in wastewater treatment and in high-density microalgae cultivation. Copyright © 2016 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Fung, Kenneth K. H.; Lewis, Geraint F.; Wu, Xiaofeng
2017-04-01
A vast wealth of literature exists on the topic of rocket trajectory optimisation, particularly in the area of interplanetary trajectories due to its relevance today. Studies on optimising interstellar and intergalactic trajectories are usually performed in flat spacetime using an analytical approach, with very little focus on optimising interstellar trajectories in a general relativistic framework. This paper examines the use of low-acceleration rockets to reach galactic destinations in the least possible time, with a genetic algorithm being employed for the optimisation process. The fuel required for each journey was calculated for various types of propulsion systems to determine the viability of low-acceleration rockets to colonise the Milky Way. The results showed that to limit the amount of fuel carried on board, an antimatter propulsion system would likely be the minimum technological requirement to reach star systems tens of thousands of light years away. However, using a low-acceleration rocket would require several hundreds of thousands of years to reach these star systems, with minimal time dilation effects since maximum velocities only reached about 0.2 c . Such transit times are clearly impractical, and thus, any kind of colonisation using low acceleration rockets would be difficult. High accelerations, on the order of 1 g, are likely required to complete interstellar journeys within a reasonable time frame, though they may require prohibitively large amounts of fuel. So for now, it appears that humanity's ultimate goal of a galactic empire may only be possible at significantly higher accelerations, though the propulsion technology requirement for a journey that uses realistic amounts of fuel remains to be determined.
NASA Astrophysics Data System (ADS)
Echevarria, M. A.; Mulholland, M. R.; Filippino, K.; Egerton, T.
2016-02-01
Algal blooms occur throughout the year in the tidal tributaries of Chesapeake Bay. The James River is the largest river in Virginia and third largest tributary of the Bay. Of the nearly 1500 species found in the estuary, two dinoflagellates; Heterocapsa triquetra and Cochlodinium polykrikoides have historically formed large seasonal algal blooms in spring and summer respectively, lasting several weeks to months annually. Additionally, the toxic dinoflagellate Alexandrium monilatum has emerged as an annual late summer bloom producer with increasing abundance in the region over the last nine years. These blooms have occurred in the lower James River, including meso- and polyhaline waters. Presented here are comparisons of the temporal and spatial extent and magnitude of these three dinoflagellate species over a two-year period (2014-2015). In 2014 dinoflagellate abundance was low compared to prior years. In contrast, massive spring and summer blooms occurred in 2015 with extended durations. In 2015, H. triquetra reached a maximum concentration of >84,000 cells/ml, with densities >103 cells/mL observed over a six week period, compared to no visible bloom the year before and a maximum of only 6200 cells/ml. Similarly in 2015, C. polykrikoides reached maximum cell densities of >41,000 cells/ml, with densities >103 cells/mL observed over a seven week period, compared to a maximum the year before of <11,000 cells/ml. A. monilatum reached a maximum of >7,500 cells/ml over a three week period in August 2015, with no bloom recorded in 2014. Multiple environmental parameters likely contributed to the interannual variability in bloom formation and duration. Temperature appeared to be a significant factor, with cooler than average surface water during the summer of 2014. In addition, the effect of prevailing wind patterns, precipitation, salinity, nutrient concentrations and sediment re-suspension were examined.
The NIH must reduce disparities in funding to maximize its return on investments from taxpayers.
Wahls, Wayne P
2018-03-23
New data from the NIH reveal that the scientific return on its sponsored research reaches a maximum at around $400,000 of annual support per principal investigator. We discuss the implications of this 'sweet spot' for funding policy, and propose that the NIH should limit both the minimum and maximum amount of funding per researcher. © 2018, Wahls et al.
The NIH must reduce disparities in funding to maximize its return on investments from taxpayers
2018-01-01
New data from the NIH reveal that the scientific return on its sponsored research reaches a maximum at around $400,000 of annual support per principal investigator. We discuss the implications of this 'sweet spot' for funding policy, and propose that the NIH should limit both the minimum and maximum amount of funding per researcher. PMID:29570053
Rajasekharan, Sivaprakash; Vercruysse, Chris; Martens, Luc; Verbeeck, Ronald
2018-01-13
Tricalcium silicate cements (TSC) are used in dental traumatology and endodontics for their bioactivity which is mostly attributed to formation of calcium hydroxide during TSC hydration and its subsequent release of calcium and hydroxide ions. The aim of this study was to determine the effect of volume (Vol), exposed surface area (ESA) and pH of surrounding medium on calcium ion release. Three commercially available hydraulic alkaline dental cements were mixed and condensed into cylindrical tubes of varying length and diameter ( n = 6/group). For the effect of ESA and Vol, tubes were immersed in 10 mL of deionized water. To analyze the effect of environmental pH, the tubes were randomly immersed in 10 mL of buffer solutions with varying pH (10.4, 7.4 or 4.4). The solutions were collected and renewed at various time intervals. pH and/or calcium ion release was measured using a pH glass electrode and atomic absorption spectrophotometer respectively. The change of pH, short-term calcium ion release and rate at which calcium ion release reaches maximum were dependent on ESA ( p < 0.05) while maximum calcium ion release was dependent on Vol of TSC ( p < 0.05). Maximum calcium ion release was significantly higher in acidic solution followed by neutral and alkaline solution ( p < 0.05).
Rajasekharan, Sivaprakash; Vercruysse, Chris; Martens, Luc; Verbeeck, Ronald
2018-01-01
Tricalcium silicate cements (TSC) are used in dental traumatology and endodontics for their bioactivity which is mostly attributed to formation of calcium hydroxide during TSC hydration and its subsequent release of calcium and hydroxide ions. The aim of this study was to determine the effect of volume (Vol), exposed surface area (ESA) and pH of surrounding medium on calcium ion release. Three commercially available hydraulic alkaline dental cements were mixed and condensed into cylindrical tubes of varying length and diameter (n = 6/group). For the effect of ESA and Vol, tubes were immersed in 10 mL of deionized water. To analyze the effect of environmental pH, the tubes were randomly immersed in 10 mL of buffer solutions with varying pH (10.4, 7.4 or 4.4). The solutions were collected and renewed at various time intervals. pH and/or calcium ion release was measured using a pH glass electrode and atomic absorption spectrophotometer respectively. The change of pH, short-term calcium ion release and rate at which calcium ion release reaches maximum were dependent on ESA (p < 0.05) while maximum calcium ion release was dependent on Vol of TSC (p < 0.05). Maximum calcium ion release was significantly higher in acidic solution followed by neutral and alkaline solution (p < 0.05). PMID:29342837
Li, Yan-Hong; Bai, Yan-Xia; Pan, Chun-Mei; Li, Wei-Wei; Zheng, Hui-Qin; Zhang, Jing-Nan; Fan, Yao-Ting; Hou, Hong-Wei
2015-12-01
The enhanced H2 production from maize straw had been achieved through the two-stage process of integrating H2 fermentation and microbial electrolysis cells (MECs) in the present work. Several key parameters affecting hydrolysis of maize straw through subcritical H2O were optimized by orthogonal design for saccharification of maize straw followed by H2 production through H2 fermentation. The maximum reducing sugar (RS) content of maize straw reached 469.7 mg/g-TS under the optimal hydrolysis condition with subcritical H2O combining with dilute HCl of 0.3% at 230 °C. The maximum H2 yield, H2 production rate, and H2 content was 115.1 mL/g-TVS, 2.6 mL/g-TVS/h, and 48.9% by H2 fermentation, respectively. In addition, the effluent from H2 fermentation was used as feedstock of MECs for additional H2 production. The maximum H2 yield of 1060 mL/g-COD appeared at an applied voltage of 0.8 V, and total COD removal reached about 35%. The overall H2 yield from maize straw reached 318.5 mL/g-TVS through two-stage processes. The structural characterization of maize straw was also carefully investigated by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD) spectra.
Toledo-Solís, F J; Uscanga-Martínez, A; Guerrero-Zárate, R; Márquez-Couturier, G; Martínez-García, R; Camarillo-Coop, S; Perales-García, N; Rodríguez-Valencia, W; Gómez-Gómez, M A; Álvarez-González, C A
2015-02-01
A study was performed in order to understand the development of digestive enzymes during initial ontogeny of Cichlasoma trimaculatum, for which the activity of acidic and alkaline proteases, lipases, amylases and phosphatases was determined by means of biochemical and electrophoretic analysis. Our results showed that the activity of alkaline proteases, trypsin and chymotrypsin is present from day 6 after hatching (dah) during exogenous feeding with Artemia nauplii. The activities of carboxypeptidase A and leucine aminopeptidase are present from the first days, increasing at 6 dah and reaching their maximum activity at 9 dah while acid protease activity started at 9 dah. Furthermore, the lipase activity is detected on 6 dah and keeps increasing and decreasing on 17 dah. Amylase activity is detected on 3 dah, presenting fluctuations until 45 dah, where it reaches its maximum activity. Acid and alkaline phosphatases are detected from 3 dah and reach a maximum activity between 13 and 19 dah. The SDS-PAGE electrophoresis revealed six types of bands in the alkaline proteases, with molecular weight between 113.4 and 20.4 kDa. First three bands appear on 6 dah, but it is until 11 dah when all isoforms appear. Based on these results, it is considered that this species completes its digestive enzymatic machinery from day 9 after hatching, therefore is recommended to perform the transition from live feed to inert feed at 15 dah.
Streamflow gain/loss in the Republican River basin, Nebraska, March 1989
Johnson, Michaela R.; Stanton, Jennifer S.; Cornwall, James F.; Landon, Matthew K.
2002-01-01
This arc and point data set contains streamflow measurement sites and reaches indicating streamflow gain or loss under base-flow conditions along the Republican River and tributaries in Nebraska during March 21 to 22, 1989 (Boohar and others, 1990). These measurements were made to obtain data on ground-water/surface-water interaction. Flow was visually observed to be zero, was measured, or was estimated at 136 sites. The measurements were made on the main stem of the Republican River and all flowing tributaries that enter the Republican River above Swanson Reservoir and parts of the Frenchman, Red Willow, and Medicine Creek drainages in the Nebraska part of the Republican River Basin. Tributaries were followed upstream until the first road crossing where zero flow was encountered. For selected streams, points of zero flow upstream of the first zero flow site were also checked. Streamflow gain or loss for each stream reach was calculated by subtracting the streamflow values measured at the upstream end of the reach and values for contributing tributaries from the downstream value. The data obtained reflected base-flow conditions suitable for estimating streamflow gains and losses for stream reaches between sites. This digital data set was created by manually plotting locations of streamflow measurements. These points were used to designate stream-reach segments to calculate gain/loss per river mile. Reach segments were created by manually splitting the lines from a 1:250,000 hydrography data set (Soenksen and others, 1999) at every location where the streams were measured. Each stream-reach segment between streamflow-measurement sites was assigned a unique reach number. All other lines in the hydrography data set without reach numbers were omitted. This data set was created to archive the calculated streamflow gains and losses of selected streams in part of the Republican River Basin, Nebraska in March 1989, and make the data available for use with geographic information systems (GIS). If measurement sites are used separately from reaches, the maximum scale of 1:100,000 should not be exceeded. When used in conjunction with the reach segments, the maximum scale should not exceed 1:250,000.
NASA Astrophysics Data System (ADS)
Krucaite, G.; Tavgeniene, D.; Xie, Z.; Lin, X.; Zhang, B.; Grigalevicius, S.
2018-02-01
Two polyethers containing electroactive pendent 4-(carbazol-2-yl)-7-arylbenzo[c]-1,2,5-thiadiazole moieties have been synthesized by the multi-step synthetic route. Full characterization of their structures is presented. The polymers represent derivatives of very high thermal stability with initial thermal degradation temperatures of 425 °C and 431 °C. Glass transition temperatures of the amorphous materials were also very high and reached values of 154 °C and 163 °C. The electron photoemission spectra of thin layers of the polymers showed ionization potentials of 5.84 eV and 5.93 eV. Hole-transporting properties of the polymeric materials were tested in the structures of organic light emitting diodes with Alq3 as the green emitter and electron transporting material. An electroluminescent device containing hole-transporting layer (HTL) of the polymer with electroactive 4-carbazolyl-7-phenylbenzo[c]-1,2,5-thiadiazole moieties exhibited turn on voltage of 6.2 V, maximum photometric efficiency of 2.5 cd/A and maximum brightness exceeding 300 cd/m2. The device containing HTL of the polymer with 4-carbazolyl-7-(1-naphtyl)benzo[c]-1,2,5-thiadiazole moieties demonstrated turn on voltage of 5.2 V, maximum photometric efficiency of 1.6 cd/A and maximum brightness exceeding 1500 cd/m2. The efficiencies were about 30-90% higher than that of the device containing widely used hole transporting layers of poly(9-vinylcarbazole).
Screw-in forces during instrumentation by various file systems.
Ha, Jung-Hong; Kwak, Sang Won; Kim, Sung-Kyo; Kim, Hyeon-Cheol
2016-11-01
The purpose of this study was to compare the maximum screw-in forces generated during the movement of various Nickel-Titanium (NiTi) file systems. Forty simulated canals in resin blocks were randomly divided into 4 groups for the following instruments: Mtwo size 25/0.07 (MTW, VDW GmbH), Reciproc R25 (RPR, VDW GmbH), ProTaper Universal F2 (PTU, Dentsply Maillefer), and ProTaper Next X2 (PTN, Dentsply Maillefer, n = 10). All the artificial canals were prepared to obtain a standardized lumen by using ProTaper Universal F1. Screw-in forces were measured using a custom-made experimental device (AEndoS- k , DMJ system) during instrumentation with each NiTi file system using the designated movement. The rotation speed was set at 350 rpm with an automatic 4 mm pecking motion at a speed of 1 mm/sec. The pecking depth was increased by 1 mm for each pecking motion until the file reach the working length. Forces were recorded during file movement, and the maximum force was extracted from the data. Maximum screw-in forces were analyzed by one-way ANOVA and Tukey's post hoc comparison at a significance level of 95%. Reciproc and ProTaper Universal files generated the highest maximum screw-in forces among all the instruments while M-two and ProTaper Next showed the lowest ( p < 0.05). Geometrical differences rather than shaping motion and alloys may affect the screw-in force during canal instrumentation. To reduce screw-in forces, the use of NiTi files with smaller cross-sectional area for higher flexibility is recommended.
[Hydrogen production and enzyme activity of acidophilic strain X-29 at different C/N ratio].
Li, Qiu-bo; Xing, De-feng; Ren, Nan-qi; Zhao, Li-hua; Song, Ye-ying
2006-04-01
Some fermentative bacteria can produce hydrogen by utilizing carbohydrate and other kinds of organic compounds as substrates. Hydrogen production was also determined by both the limiting of growth and related enzyme activity in energy metabolism. Carbon and nitrogen are needed for the growth and metabolism of microorganisms. In addition, the carbon/nitrogen (C/N) ratio can influence the material metabolized and the energy produced. In order to improve the hydrogen production efficiency of the bacteria, we analyzed the effect of different C/N ratios on hydrogen production and the related enzyme activities in the acidophilic strain X-29 using batch test. The results indicate that the differences in the metabolism level and enzyme activity are obvious at different C/N ratios. Although the difference in liquid fermentative products produced per unit of biomass is not obvious, hydrogen production is enhanced at a specifically determined ratio. At a C/N ratio of 14 the accumulative hydrogen yield of strain X-29 reaches the maximum, 2210.9 mL/g. At different C/N ratios, the expression of hydrogenase activity vary; the activity of hydrogenase decrease quickly after reaching a maximum along with the fermentation process, but the time of expression is short. The activity of alcohol dehydrogenase (ADH) tend to stabilize after reaching a peak along with the fermentation process, the difference in expression activity is little, and the expression period is long at different C/N ratios. At a C/N ratio of 14 hydrogenase and ADH reach the maximum 2.88 micromol x (min x mg)(-1) and 33.2 micromol x (min x mg)(-1), respectively. It is shown that the C/N ratio has an important effect on enhancing hydrogen production and enzyme activity.
Mina, Sara; Staerck, Cindy; d'Almeida, Sènan M; Marot, Agnès; Delneste, Yves; Calenda, Alphonse; Tabiasco, Julie; Bouchara, Jean-Philippe; Fleury, Maxime J J
2015-12-01
Scedosporium boydii is an opportunistic filamentous fungus which may be responsible for a large variety of infections in both immunocompetent and immunocompromised individuals. This fungus belongs to the Scedosporium apiospermum species complex which usually ranks second among the filamentous fungi colonizing the airways of patients with cystic fibrosis (CF). Species of the S. apiospermum complex are able to chronically colonize the CF airways suggesting pathogenic mechanisms allowing persistence and growth of these fungi in the respiratory tract. Few putative virulence factors have been purified and characterized so far in the S. apiospermum complex including a cytosolic Cu,Zn-superoxide dismutase (SOD) and a monofunctional catalase (catalase A1). Upon microbial infection, host phagocytes release reactive oxygen species (ROS), such as hydrogen peroxide, as part of the antimicrobial response. Catalases are known to protect pathogens against ROS by degradation of the hydrogen peroxide. Here, we identified the S. boydii catalase A1 gene (CATA1) and investigated its expression in response to the environmental conditions encountered in the CF airways and to the oxidative stress. Results showed that S. boydii CATA1 gene expression is not affected by hypoxia, hypercapnia or pH changes. In contrast, CATA1 gene was overexpressed in response to a chemically induced oxidative stress with a relative gene expression 37-fold higher in the presence of 250 μM H(2)O(2), 20-fold higher with 250 μM menadione and 5-fold higher with 2 mM paraquat. Moreover, S. boydii CATA1 gene expression progressively increased upon exposure to activated THP-1-derived macrophages, reaching a maximum after 12 h (26 fold). Activated HL60-derived neutrophils and activated human peripheral blood neutrophils more rapidly induced S. boydii CATA1 gene overexpression, a maximum gene expression level being reached at 75 min (17 fold) and 60 min (15 fold), respectively. In contrast expression of the gene encoding the Cu,Zn-SOD (SODC gene) was not affected by H(2)O(2), menadione, paraquat or in co-culture with phagocytic cells. These results suggest that S. boydii CATA1 gene is highly stimulated by the oxidative burst response whereas SODC gene is constitutively expressed. Copyright © 2015 The British Mycological Society. Published by Elsevier Ltd. All rights reserved.
Transient ice mass variations over Greenland detected by the combination of GPS and GRACE data
NASA Astrophysics Data System (ADS)
Zhang, B.; Liu, L.; Khan, S. A.; van Dam, T. M.; Zhang, E.
2017-12-01
Over the past decade, the Greenland Ice Sheet (GrIS) has been undergoing significant warming and ice mass loss. Such mass loss was not always a steady process but had substantial temporal and spatial variabilities. Here we apply multi-channel singular spectral analysis to crustal deformation time series measured at about 50 Global Positioning System (GPS) stations mounted on bedrock around the Greenland coast and mass changes inferred from Gravity Recovery and Climate Experiment (GRACE) to detect transient changes in ice mass balance over the GrIS. We detect two transient anomalies: one is a negative melting anomaly (Anomaly 1) that peaked around 2010; the other is a positive melting anomaly (Anomaly 2) that peaked between 2012 and 2013. The GRACE data show that both anomalies caused significant mass changes south of 74°N but negligible changes north of 74°N. Both anomalies caused the maximum mass change in southeast GrIS, followed by in west GrIS near Jakobshavn. Our results also show that the mass change caused by Anomaly 1 first reached the maximum in late 2009 in the southeast GrIS and then migrated to west GrIS. However, in Anomaly 2, the southeast GrIS was the last place that reached the maximum mass change in early 2013 and the west GrIS near Jakobshavn was the second latest place that reached the maximum mass change. Most of the GPS data show similar spatiotemporal patterns as those obtained from the GRACE data. However, some GPS time series show discrepancies in either space or time, because of data gaps and different sensitivities of mass loading change. Namely, loading deformation measured by GPS can be significantly affected by local dynamical mass changes, which, yet, has little impact on GRACE observations.
Kanyerere, Henry; Harries, Anthony D; Tayler-Smith, Katie; Jahn, Andreas; Zachariah, Rony; Chimbwandira, Frank M; Mpunga, James
2016-01-01
Since 1985, Malawi has experienced a dual epidemic of HIV and tuberculosis (TB) which has been moderated recently by the advent of antiretroviral therapy (ART). The aim of this study was to describe the association over several decades between HIV/AIDS, the scale-up of ART and TB case notifications. Aggregate data were extracted from annual reports of the National TB Control Programme, the Ministry of Health HIV Department and the National Statistics Office. ART coverage was calculated using the total HIV population as denominator (derived from UNAIDS Spectrum software). In 1970, there were no HIV-infected persons but numbers had increased to a maximum of 1.18 million by 2014. HIV prevalence reached a maximum of 10.8% in 2000, thereafter decreasing to 7.5% by 2014. Numbers alive on ART increased from 2586 in 2003 to 536 527 (coverage 45.3%) by 2014. In 1985, there were 5286 TB cases which reached a maximum of 28 234 in 2003 and then decreased to 17 723 by 2014 (37% decline from 2003). There were increases in all types of new TB between 1998-2003 which then declined by 30% for extrapulmonary TB, by 37% for new smear-positive PTB and by 50% for smear-negative PTB. Previously treated TB cases reached a maximum of 3443 in 2003 and then declined by 42% by 2014. The rise and fall of TB in Malawi between 1985 and 2014 was strongly associated with HIV infection and ART scale-up; this has implications for ending the TB epidemic in high HIV-TB burden countries. © 2015 The Authors. Tropical Medicine & International Health Published by John Wiley & Sons Ltd.
Tsunami Risk Assessment Modelling in Chabahar Port, Iran
NASA Astrophysics Data System (ADS)
Delavar, M. R.; Mohammadi, H.; Sharifi, M. A.; Pirooz, M. D.
2017-09-01
The well-known historical tsunami in the Makran Subduction Zone (MSZ) region was generated by the earthquake of November 28, 1945 in Makran Coast in the North of Oman Sea. This destructive tsunami killed over 4,000 people in Southern Pakistan and India, caused great loss of life and devastation along the coasts of Western India, Iran and Oman. According to the report of "Remembering the 1945 Makran Tsunami", compiled by the Intergovernmental Oceanographic Commission (UNESCO/IOC), the maximum inundation of Chabahar port was 367 m toward the dry land, which had a height of 3.6 meters from the sea level. In addition, the maximum amount of inundation at Pasni (Pakistan) reached to 3 km from the coastline. For the two beaches of Gujarat (India) and Oman the maximum run-up height was 3 m from the sea level. In this paper, we first use Makran 1945 seismic parameters to simulate the tsunami in generation, propagation and inundation phases. The effect of tsunami on Chabahar port is simulated using the ComMIT model which is based on the Method of Splitting Tsunami (MOST). In this process the results are compared with the documented eyewitnesses and some reports from researchers for calibration and validation of the result. Next we have used the model to perform risk assessment for Chabahar port in the south of Iran with the worst case scenario of the tsunami. The simulated results showed that the tsunami waves will reach Chabahar coastline 11 minutes after generation and 9 minutes later, over 9.4 Km2 of the dry land will be flooded with maximum wave amplitude reaching up to 30 meters.
Schecklmann, Martin; Vielsmeier, Veronika; Steffens, Thomas; Landgrebe, Michael; Langguth, Berthold; Kleinjung, Tobias
2012-01-01
Background Different mechanisms have been proposed to be involved in tinnitus generation, among them reduced lateral inhibition and homeostatic plasticity. On a perceptual level these different mechanisms should be reflected by the relationship between the individual audiometric slope and the perceived tinnitus pitch. Whereas some studies found the tinnitus pitch corresponding to the maximum hearing loss, others stressed the relevance of the edge frequency. This study investigates the relationship between tinnitus pitch and audiometric slope in a large sample. Methodology This retrospective observational study analyzed 286 patients. The matched tinnitus pitch was compared to the frequency of maximum hearing loss and the edge of the audiogram (steepest hearing loss) by t-tests and correlation coefficients. These analyses were performed for the whole group and for sub-groups (uni- vs. bilateral (117 vs. 338 ears), pure-tone vs. narrow-band (340 vs. 115 ears), and low and high audiometric slope (114 vs. 113 ears)). Findings For the right ear, tinnitus pitch was in the same range and correlated significantly with the frequency of maximum hearing loss, but differed from and did not correlate with the edge frequency. For the left ear, similar results were found but the correlation between tinnitus pitch and maximum hearing loss did not reach significance. Sub-group analyses (bi- and unilateral, tinnitus character, slope steepness) revealed identical results except for the sub-group with high audiometric slope which revealed a higher frequency of maximum hearing loss as compared to the tinnitus pitch. Conclusion The study-results confirm a relationship between tinnitus pitch and maximum hearing loss but not to the edge frequency, suggesting that tinnitus is rather a fill-in-phenomenon resulting from homeostatic mechanisms, than the result of deficient lateral inhibition. Sub-group analyses suggest that audiometric steepness and the side of affected ear affect this relationship. Future studies should control for these potential confounding factors. PMID:22529949
Soil pollution by oxidation of tailings from toxic spill of a pyrite mine.
Simón, M; Martín, F; Ortiz, I; García, I; Fernández, J; Fernández, E; Dorronsoro, C; Aguilar, J
2001-11-12
On the 25th April 1998, toxic water and tailings from a pyrite mine of Aznalcóllar (southern Spain) spilled into the Agrio and Guadiamar River Basin affecting some 40 km2. In five sectors throughout the basin, we monitored the physical and chemical properties of the tailings as well as the degree of pollution in the soils on four different sampling dates: 5 May, 20 May, 4 June and 22 July 1998. The characteristics of the tailings deposited on the soils are shown to be related to distance from the spill. The oxidation rate of the tailings and the solubilization of the pollutant elements were more pronounced in the middle and lower sectors of the basin, where the particle size was finer, the sulfur content higher and the bulk density less. The increases in water-soluble sulfates, Zn. Cd and Cu were very rapid (the highest values being reached 25 days after the spill) and intense (reaching 45% of the total Cu, 65% of the total Zn and Cd). Meanwhile, the increases in water-soluble As, Bi, Sb, Pb and Tl were far lower (ranging between 0.002% of the total Tl and 2.5% of the total As) and less rapid in the case of As, Bi and Pb (the highest values for these elements being reached 40 days after the spill). These soluble elements infiltrated the soils with the rainwater, swiftly augmenting the soil pollution. Twenty-five days after the spill, when the rainfall ranged between 45 and 63 mm, the first 10-cm of the soils in the middle and lower sectors of the basin exceeded the maximum concentration permitted for agricultural soils in Zn, Cu and Tl. At 40 days after the spill, when the rainfall ranged between 60 and 89 mm, all the soils reached or exceeded the maximum permitted concentrations for As and Tl. Nevertheless, the pollutants tended to concentrate in the first 10 cm of the soils without seriously contaminating either the subsoil or the groundwaters. Consequently, a rapid removal of the tailings and the ploughing of the first 25-30 cm of the soils would be urgent measures to diminish pollutant concentration in the soils affected by the spill.
Photothermal Radiometry and Diffuse Reflectance Analysis of Thermally Treated Bones
NASA Astrophysics Data System (ADS)
Trujillo, S.; Martínez-Torres, P.; Quintana, P.; Alvarado-Gil, Juan Jose
2010-05-01
Different fields such as archaeology, biomedicine, forensic science, and pathology involve the analysis of burned bones. In this work, the effects of successive thermal treatments on pig long bones, measured by photothermal radiometry and diffuse reflectance are reported. Measurements were complemented by X-ray diffraction and infrared spectroscopy. Samples were thermally treated for 1 h within the range of 25 °C to 350 °C. The thermal diffusivity and reflectance increase in the low-temperature range, reaching a maximum around 125 °C and decaying at higher temperatures. These results are the consequence of complex modifications occurring in the inorganic and organic bone structure. For lower temperatures dehydration, dehydroxilation, and carbonate loss processes are dominant, followed by collagen denaturing and decompositions, which have an influence on the bone microstructure.
NASA Astrophysics Data System (ADS)
Palermo, C.; Torres, J.; Varani, L.; Gružinskis, V.; Starikov, E.; Shiktorov, P.; Ašmontas, S.; Sužiedelis, A.
2017-10-01
Electron transport and drain current noise in the wurtzite GaN MOSFET have been studied by Monte Carlo particle simulation which simultaneously solves the Boltzmann transport and pseudo-2D Poisson equations. A proper design of GaN MOSFET n+nn+ channel with uncentered gate in n-region to reach the maximum detection sensitivity is proposed. It is shown that the main role in formation of longitudinal transport asymmetry and THz radiation detection is played by optical phonon emission process. It is found that the detection current at 300 K is maximal in frequency range from 0.5 to 7 THz. At higher frequenciea the detection current rapidly decreases due to the inertia of electron motion.
NASA Astrophysics Data System (ADS)
Özer, Mustafa M.; Weitering, Hanno H.
2013-07-01
Deposition of Mg on Si(111)7 × 7 produces an epitaxial magnesium silicide layer. Under identical annealing conditions, the thickness of this Mg2Si(111) layer increases with deposition amount, reaching a maximum of 4 monolayer (ML) and decreasing to ˜3 ML at higher Mg coverage. Excess Mg coalesces into atomically flat, crystalline Mg(0001) films. This surprising growth mode can be attributed to the accidental commensurability of the Mg(0001), Si(111), and Mg2Si(111) interlayer spacing and the concurrent minimization of in-plane Si mass transfer and domain-wall energies. The commensurability of the interlayer spacing defines a highly unique solid-phase epitaxial growth process capable of producing trilayer structures with atomically abrupt interfaces and atomically smooth surface morphologies.
Light up-conversion from near-infrared to blue using a photoresponsive organic light-emitting device
NASA Astrophysics Data System (ADS)
Chikamatsu, Masayuki; Ichino, Yoshiro; Takada, Noriyuki; Yoshida, Manabu; Kamata, Toshihide; Yase, Kiyoshi
2002-07-01
A photoresponsive organic light-emitting device combining blue-emitting organic electroluminescent (EL) diode with titanyl phthalocyanine as a near-infrared (IR) sensitive layer was fabricated. By irradiating near-IR light to the device, blue emission occurred in the lower drive voltage (between 5 and 12 V). The result indicates that the device acts as a light switch and/or an up-converter from near-IR light (1.6 eV) to blue (2.6 eV). The EL response times of rise and decay using a near-IR light trigger were 260 and 330 mus, respectively. At a higher voltage (above 12 V), enhancement of blue emission was observed with near-IR light irradiation. The ON/OFF ratio reached a maximum of 103.
Optimization of a high-pressure pore water extraction device.
Cyr, Martin; Daidié, Alain
2007-02-01
High-pressure squeezing is a technique used for the extraction of the pore water of porous materials such as sediments, soils, rocks, and concrete. The efficiency of extraction depends on the maximum pressures on the materials. This article presents the design of a high-pressure device reaching an axial pressure of 1000 MPa which has been developed to improve the efficiency of extraction. The increase in squeezing pressure implies high stresses inside the chamber, so specialized expertise was required to design a safe, functional device that could withstand pressures significantly higher than common laboratory equipment. The design includes finite element calculations, selection of appropriate materials, and descriptive construction details for the apparatus. It also includes an experimental study of the performance of the apparatus in terms of extraction efficiency.
Using multiple linear regression model to estimate thunderstorm activity
NASA Astrophysics Data System (ADS)
Suparta, W.; Putro, W. S.
2017-03-01
This paper is aimed to develop a numerical model with the use of a nonlinear model to estimate the thunderstorm activity. Meteorological data such as Pressure (P), Temperature (T), Relative Humidity (H), cloud (C), Precipitable Water Vapor (PWV), and precipitation on a daily basis were used in the proposed method. The model was constructed with six configurations of input and one target output. The output tested in this work is the thunderstorm event when one-year data is used. Results showed that the model works well in estimating thunderstorm activities with the maximum epoch reaching 1000 iterations and the percent error was found below 50%. The model also found that the thunderstorm activities in May and October are detected higher than the other months due to the inter-monsoon season.
NASA Technical Reports Server (NTRS)
2004-01-01
KENNEDY SPACE CENTER, FLA. In this view from the floor of the Orbiter Processing Facility, the first of three Space Shuttle Main Engines (SSME) is seen after installation. Discovery is the vehicle designated for the Return to Flight mission STS-114. Overall, an SSME weighs approximately 7,000 pounds. An SSME operates at greater temperature extremes than any mechanical system in common use today. The liquid hydrogen fuel is -423 degrees Fahrenheit, the second coldest liquid on Earth. When the hydrogen is burned with liquid oxygen, the temperature in the engine's combustion chamber reaches +6000 degrees Fahrenheit -- that's higher than the boiling point of Iron. The maximum equivalent horsepower developed by the three SSMEs is just over 37 million horsepower. The energy released by the three SSMEs is equivalent to the output of 23 Hoover Dams.
NASA Technical Reports Server (NTRS)
2004-01-01
KENNEDY SPACE CENTER, FLA. In the Orbiter Processing Facility, technicians wait below while a Hyster lift moves the first of three Space Shuttle Main Engines (SSME) into position above for installation on Discovery, the vehicle designated for the Return to Flight mission STS-114. Overall, an SSME weighs approximately 7,000 pounds. An SSME operates at greater temperature extremes than any mechanical system in common use today. The liquid hydrogen fuel is -423 degrees Fahrenheit, the second coldest liquid on Earth. When the hydrogen is burned with liquid oxygen, the temperature in the engine's combustion chamber reaches +6000 degrees Fahrenheit -- that's higher than the boiling point of Iron. The maximum equivalent horsepower developed by the three SSMEs is just over 37 million horsepower. The energy released by the three SSMEs is equivalent to the output of 23 Hoover Dams.
NASA Technical Reports Server (NTRS)
2004-01-01
KENNEDY SPACE CENTER, FLA. In this closeup view, the first of three Space Shuttle Main Engines (SSME) is seen after installation on Discovery in the Orbiter Processing Facility. Discovery is the vehicle designated for the Return to Flight mission STS-114. Overall, an SSME weighs approximately 7,000 pounds. An SSME operates at greater temperature extremes than any mechanical system in common use today. The liquid hydrogen fuel is -423 degrees Fahrenheit, the second coldest liquid on Earth. When the hydrogen is burned with liquid oxygen, the temperature in the engine's combustion chamber reaches +6000 degrees Fahrenheit -- that's higher than the boiling point of Iron. The maximum equivalent horsepower developed by the three SSMEs is just over 37 million horsepower. The energy released by the three SSMEs is equivalent to the output of 23 Hoover Dams.
NASA Technical Reports Server (NTRS)
2004-01-01
KENNEDY SPACE CENTER, FLA. In the Orbiter Processing Facility, the Hyster lift backs away from the orbiter Discovery after placing a Space Shuttle Main Engine (SSME) into position for installation. Discovery is the vehicle designated for the Return to Flight mission STS-114. Overall, an SSME weighs approximately 7,000 pounds. An SSME operates at greater temperature extremes than any mechanical system in common use today. The liquid hydrogen fuel is -423 degrees Fahrenheit, the second coldest liquid on Earth. When the hydrogen is burned with liquid oxygen, the temperature in the engine's combustion chamber reaches +6000 degrees Fahrenheit -- that's higher than the boiling point of Iron. The maximum equivalent horsepower developed by the three SSMEs is just over 37 million horsepower. The energy released by the three SSMEs is equivalent to the output of 23 Hoover Dams.
NASA Technical Reports Server (NTRS)
2004-01-01
KENNEDY SPACE CENTER, FLA. In the Orbiter Processing Facility, a technician (lower right) watches from inside as a Space Shuttle Main Engine (SSME) on the Hyster lift is maneuvered into position on Discovery, the vehicle designated for the Return to Flight mission STS-114. Overall, an SSME weighs approximately 7,000 pounds. An SSME operates at greater temperature extremes than any mechanical system in common use today. The liquid hydrogen fuel is -423 degrees Fahrenheit, the second coldest liquid on Earth. When the hydrogen is burned with liquid oxygen, the temperature in the engine's combustion chamber reaches +6000 degrees Fahrenheit -- that's higher than the boiling point of Iron. The maximum equivalent horsepower developed by the three SSMEs is just over 37 million horsepower. The energy released by the three SSMEs is equivalent to the output of 23 Hoover Dams.
NASA Technical Reports Server (NTRS)
2004-01-01
KENNEDY SPACE CENTER, FLA. In the Orbiter Processing Facility, Discovery waits as the first of three Space Shuttle Main Engines (SSME) moves into position for installation on Discovery, the vehicle designated for the Return to Flight mission STS-114. Overall, an SSME weighs approximately 7,000 pounds. An SSME operates at greater temperature extremes than any mechanical system in common use today. The liquid hydrogen fuel is -423 degrees Fahrenheit, the second coldest liquid on Earth. When the hydrogen is burned with liquid oxygen, the temperature in the engine's combustion chamber reaches +6000 degrees Fahrenheit -- that's higher than the boiling point of Iron. The maximum equivalent horsepower developed by the three SSMEs is just over 37 million horsepower. The energy released by the three SSMEs is equivalent to the output of 23 Hoover Dams.
Shock heating of the solar wind plasma
NASA Technical Reports Server (NTRS)
Whang, Y. C.; Liu, Shaoliang; Burlaga, L. F.
1990-01-01
The role played by shocks in heating solar-wind plasma is investigated using data on 413 shocks which were identified from the plasma and magnetic-field data collected between 1973 and 1982 by Pioneer and Voyager spacecraft. It is found that the average shock strength increased with the heliocentric distance outside 1 AU, reaching a maximum near 5 AU, after which the shock strength decreased with the distance; the entropy of the solar wind protons also reached a maximum at 5 AU. An MHD simulation model in which shock heating is the only heating mechanism available was used to calculate the entropy changes for the November 1977 event. The calculated entropy agreed well with the value calculated from observational data, suggesting that shocks are chiefly responsible for heating solar wind plasma between 1 and 15 AU.
Andersen, L T
1985-01-01
Development of a painful shoulder in the hemiplegic patient is a significant and serious problem, because it can limit the patient's ability to reach his or her maximum functional potential. Several etiologies of shoulder pain have been identified, such as immobilization of the upper extremity, trauma to the joint structures, including brachial plexus injuries, and subluxation of the gleno-humeral joint. A review of the literature explains the basic anatomy and kinesiology of the shoulder complex, the various etiologies of hemiplegic shoulder pain, and the pros and cons of specific treatment techniques. This knowledge is essential for the occupational therapist to evaluate effectively techniques used to treat the patient with hemiplegic shoulder pain. More effective management of this problem will facilitate the patient's ability to reach his or her maximum functional potential.
Lijnen, P; Fagard, R; Staessen, J; Amery, A
1981-01-01
1 Chronic treatment with a constant dose of hydrochlorothiazide or tienilic acid increases plasma renin activity (PRA) acutely to reach a maximum within the first week. 2 During chronic diuretic therapy from 1 month to 1 year, PRA remained elevated at a rather constant level, though this was somewhat lower than the maximum level reached after 1 week. 3 A significant (P less than 0.01) correlation (r = 0.74) between changes in plasma angiotensin II and renin activity provoked by chronic treatment for 3 months with hydrochlorothiazide and tienilic acid was found. 4 The increase in plasma aldosterone during chronic treatment with hydrochlorothiazide and tienilic acid (1000 mg) is related (r = 0.68; P less than 0.01) to the rise in plasma angiotensin II. PMID:7028060
Impact of mixing state and hygroscopicity on CCN activity of biomass burning aerosol in Amazonia
NASA Astrophysics Data System (ADS)
Sánchez Gácita, Madeleine; Longo, Karla M.; Freire, Julliana L. M.; Freitas, Saulo R.; Martin, Scot T.
2017-02-01
Smoke aerosols prevail throughout Amazonia because of widespread biomass burning during the dry season, and external mixing, low variability in the particle size distribution and low particle hygroscopicity are typical. There can be profound effects on cloud properties. This study uses an adiabatic cloud model to simulate the activation of smoke particles as cloud condensation nuclei (CCN) for three hypothetical case studies, chosen as to resemble biomass burning aerosol observations in Amazonia. The relative importance of variability in hygroscopicity, mixing state, and activation kinetics for the activated fraction and maximum supersaturation is assessed. For a population with κp = 0.04, an overestimation of the cloud droplet number concentration Nd for the three selected case studies between 22.4 ± 1.4 and 54.3 ± 3.7 % was obtained when assuming a hygroscopicity parameter κp = 0.20. Assuming internal mixing of the aerosol population led to overestimations of up to 20 % of Nd when a group of particles with medium hygroscopicity was present in the externally mixed population cases. However, the overestimations were below 10 % for external mixtures between very low and low-hygroscopicity particles, as seems to be the case for Amazon smoke particles. Kinetic limitations were significant for medium- and high-hygroscopicity particles, and much lower for very low and low-hygroscopicity particles. When particles were assumed to be at equilibrium and to respond instantly to changes in the air parcel supersaturation, the overestimation of the droplet concentration was up to ˜ 100 % in internally mixed populations, and up to ˜ 250 % in externally mixed ones, being larger for the higher values of hygroscopicity. In addition, a perceptible delay between the times when maximum supersaturation and maximum aerosol activated fraction are reached was noticed and, for aerosol populations with effective hygroscopicity κpeff higher than a certain threshold value, the delay in particle activation was such that no particles were activated at the time of maximum supersaturation. Considering internally mixed populations, for an updraft velocity W = 0.5 m s-1 this threshold of no activation varied between κpeff = 0.35 and κpeff = 0.5 for the different case studies. However, for low hygroscopicity, kinetic limitations played a weaker role for CCN activation of particles, even when taking into account the large aerosol mass and number concentrations. For the very low range of hygroscopicities, the overestimation of the droplet concentration due to the equilibrium assumption was lowest and the delay between the times when maximum supersaturation and maximum activated fraction were reached was greatly reduced or no longer observed (depending on the case study). These findings on uncertainties and sensitivities provide guidance on appropriate simplifications that can be used for modeling of smoke aerosols within general circulation models. The use of medium values of hygroscopicity representative of smoke aerosols for other biomass burning regions on Earth can lead to significant errors compared to the use of low hygroscopicity for Amazonia (between 0.05 and 0.13, according to available observations). Also in this region, consideration of the biomass burning population as internally mixed will lead to small errors in the droplet concentration, while significantly increasing the computational burden. Regardless of the large smoke aerosol loads in the region during the dry season, kinetic limitations are expected to be low.
Dependence of Some Mechanical Properties of Elastic Bands on the Length and Load Time
ERIC Educational Resources Information Center
Triana, C. A.; Fajardo, F.
2012-01-01
We present a study of the maximum stress supported by elastics bands of nitrile as a function of the natural length and the load time. The maximum tension of rupture and the corresponding variation in length were found by measuring the elongation of an elastic band when a mass is suspended from its free end until it reaches the breaking point. The…
The Structural Formation and Physical Behaviour of Cross-Linked Epoxy Resins
1981-04-01
analysis , at which the heat evolution reaches a maximum, may be used for purposes of characterisation. Aliphatic polyamines react mere quickly than the...DTA, DSC), thermomechanical analysis (TMA), torsional vibration analysis (TVA), deter- mination of the dimensional stability under heat (eq ISO R 75 or...obtained by thermomechanical analysis , taking the temperature of maximum velocity of penetration of a loaded probe (rate of heating - 10°C/min
Merchán-Baeza, Jose Antonio; González-Sánchez, Manuel; Cuesta-Vargas, Antonio Ignacio
2014-01-01
Postural instability is one of the major complications found in stroke survivors. Parameterising the functional reach test (FRT) could be useful in clinical practice and basic research. To analyse the reliability, sensitivity, and specificity in the FRT parameterisation using inertial sensors for recording kinematic variables in patients who have suffered a stroke. Cross-sectional study. While performing FRT, two inertial sensors were placed on the patient's back (lumbar and trunk). Five subjects over 65 who suffer from a stroke. FRT measures, lumbosacral/thoracic maximum angular displacement, maximum time of lumbosacral/thoracic angular displacement, time return initial position, and total time. Speed and acceleration of the movements were calculated indirectly. FRT measure is 12.75±2.06 cm. Intrasubject reliability values range from 0.829 (time to return initial position (lumbar sensor)) to 0.891 (lumbosacral maximum angular displacement). Intersubject reliability values range from 0.821 (time to return initial position (lumbar sensor)) to 0.883 (lumbosacral maximum angular displacement). FRT's reliability was 0.987 (0.983-0.992) and 0.983 (0.979-0.989) intersubject and intrasubject, respectively. The main conclusion could be that the inertial sensors are a tool with excellent reliability and validity in the parameterization of the FRT in people who have had a stroke.
Geomorphic impact of the 16S 2015 tsunami event in the Coquimbo Bay (Northern Chile)
NASA Astrophysics Data System (ADS)
Abad, Manuel; Izquierdo, Tatiana; Lock, Suan-lin; Rojas, Diego; Fritis, Eduardo
2017-04-01
On September 16, 2105 a Mw 8.3 earthquake occurred at 22:55 GTM with a focal depth of 23 km and an epicenter located 31.570°S, W 71.670°, in the Coquimbo Region (northern Chile). This event triggered a tsunami with wave heights of more than 6 m that caused damages and flooding in the northern Chilean coast, mainly in the cities of Tongoy and Coquimbo - La Serena. The vertical run-up shows an important saw-tooth like variation due to the sharp changes in the topography, specially towards both ends of the bay. The highest and more irregular values occurred in the South sector, that presents a higher topographic gradient, and progressively decrease towards the North were the topography is flatter. The horizontal flooding reached its maximum values in the bay fluvial valleys where the tsunami wave entered along the river channels. The waves, favored by the confining conditions, entered more than 950 m in the Elqui River mouth and almost 700 m in the Culebrón Stream. Coquimbo Bay comprises a wide and convex littoral zone of approximately 18 km long only interrupted by the mouths of the Elqui River and the Culebrón Stream where small saltmarshes have developed. According to the tide gauge data, the first wave reached the Coquimbo coast only 20 minutes after the earthquake with a maximum height of 0.85 m. 22 minutes later, a second wave arrived with a much higher height (4.3 m) causing the first damages on the littoral and the city. The last wave, the 4th one, occurred 35 minutes after the earthquake and was the highest reaching 4.68 m as well as the most damaging. Despite the existence of works that analyze the characteristics of this event, a more deep and thorough study is still needed of the tsunami geological record in the Coquimbo Bay where a wide variety of forms and deposits were preserved. The making of a geomorphological map has allowed us to differentiate the geological features related with the tsunamigenic event such as sand sheets and debris-boulder fields (tsunamites), littoral erosion scars developed on the saltmarshes, beaches and coastal dunes, erosive backwash channels, degraded wetlands, flooding lagoons or the appearance of new fluvial channels. This morpho-sedimentary assemblage, all together, has enabled us to characterize the conditions in which the tsunami occurred and to quantify it effects along this coastal zone as well their potential preservation.
Rösch, Carolin; Wissenbach, Dirk K; von Bergen, Martin; Franck, Ulrich; Wendisch, Manfred; Schlink, Uwe
2015-09-01
Atmospheric ozone-terpene reactions, which form secondary organic aerosol (SOA) particles, can affect indoor air quality when outdoor air mixes with indoor air during ventilation. This study, conducted in Leipzig, Germany, focused on limonene-induced particle formation in a genuine indoor environment (24 m(3)). Particle number, limonene and ozone concentrations were monitored during the whole experimental period. After manual ventilation for 30 min, during which indoor ozone levels reached up to 22.7 ppb, limonene was introduced into the room at concentrations of approximately 180 to 250 μg m(-3). We observed strong particle formation and growth within a diameter range of 9 to 50 nm under real-room conditions. Larger particles with diameters above 100 nm were less affected by limonene introduction. The total particle number concentrations (TPNCs) after limonene introduction clearly exceed outdoor values by a factor of 4.5 to 41 reaching maximum concentrations of up to 267,000 particles cm(-3). The formation strength was influenced by background particles, which attenuated the formation of new SOA with increasing concentration, and by ozone levels, an increase of which by 10 ppb will result in a six times higher TPNC. This study emphasizes indoor environments to be preferred locations for particle formation and growth after ventilation events. As a consequence, SOA formation can produce significantly higher amounts of particles than transported by ventilation into the indoor air.
Oil Production by a Consortium of Oleaginous Microorganisms grown on primary effluent wastewater
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hall, Jacqueline; Hetrick, Mary; French, Todd
Municipal wastewater could be a potential growth medium that has not been considered for cultivating oleaginous microorganisms. This study is designed to determine if a consortium of oleaginous microorganism can successfully compete for carbon and other nutrients with the indigenous microorganisms contained in primary effluent wastewater. RESULTS: The oleaginous consortium inoculated with indigenous microorganisms reached stationary phase within 24 h, reaching a maximum cell concentration of 0.58 g L -1. Water quality post-oleaginous consortium growth reached a maximum chemical oxygen demand (COD) reduction of approximately 81%, supporting the consumption of the glucose within 8 h. The oleaginous consortium increased themore » amount of oil produced per gram by 13% compared with indigenous microorganisms in raw wastewater. Quantitative polymerase chain reaction (qPCR) results show a substantial population increase in bacteria within the first 24 h when the consortium is inoculated into raw wastewater. This result, along with the fatty acid methyl esters (FAMEs) results, suggests that conditions tested were not sufficient for the oleaginous consortium to compete with the indigenous microorganisms.« less
Lee, Simon; Cvetanovich, Gregory L.; Mascarenhas, Randy; Wuerz, Thomas H.; Mather, Richard C.; Bush-Joseph, Charles A.
2017-01-01
Abstract The purpose of this study was to investigate the ability of worker’s compensation (WC) patients to return to work without restrictions after hip arthroscopy. Twenty-nine WC patients along with age and gender matched controls who underwent hip arthroscopy were retrospectively reviewed after achieving maximum medical improvement (MMI) status at minimum 1 year postoperatively. Patient demographic factors were evaluated, along with the Hip Outcome Score Activities of Daily Living and Sports-Specific subscales, and the modified Harris Hip Score (mHHS). The majority of WC patients were able to return to work without restrictions after reaching MMI (20/29, 69.0%). WC patients who failed to return to work without restrictions had a prolonged time from injury to surgery (3.01 ± 2.16 months versus 6.36 ± 4.16 months; P = 0.0079), more concomitant orthopedic injuries (4/20, 20.0% versus 9/9, 100%; P = 0.0001), and higher body mass index (BMI) (26.61 ± 3.52 versus 29.54 ± 3.43; P = 0.047) than those who returned to work without restrictions. WC patients had significant improvement of patient-reported outcome scores following hip arthroscopy (P < 0.0001), but WC patients who returned to work without restrictions had higher scores than those who failed to do so (HOD-ADL: P < 0.0001; HOS-SS: P = 0.004; mHHS: P = 0.009). The majority of WC patients are able to return to work without restrictions when they reach MMI status following hip arthroscopy. Factors associated with failure to return to work without restrictions include prolonged time course between injury and surgical treatment, concomitant orthopaedic injuries, and a higher BMI. Level III, retrospective case-control study PMID:28630718
Porru, Emanuele; Franco, Placido; Calabria, Donato; Spinozzi, Silvia; Roberti, Marinella; Caliceti, Cristiana; Roda, Aldo
2018-06-01
Berberine (BBR) is a natural alkaloid obtained from Berberis species plants, known for its protective effects against several diseases. Among the primary BBR metabolites, berberrubine (M1) showed the highest plasma concentration but few and conflicting data are available regarding its concentration in biological fluids related to its new potential activity on vascular cells. A combined analytical approach was applied to study biodistribution of M1 in comparison with BBR. The optimization of sample clean-up combined with a fully validated HPLC-ESI-MS/MS tailored for M1 allows sufficient detectability and accuracy to be reached in the different studied organs even when administered at low dose, comparable to that assumed by human. A predictive human vascular endothelial cell-based assay to measure intracellular xanthine oxidase has been developed and applied to study unexplored activities of M1 alongside other common activities. Results showed that oral M1 treatment exhibits higher plasma levels than BBR, reaching maximum concentration 400-fold higher than BBR (204 vs 0.5 ng/mL); moreover, M1 exhibits higher concentrations than BBR also in all the biological compartments analyzed. Noteworthy, the two compounds follow two different excretion routes: M1 through urine, while BBR through feces. In vitro studies demonstrated that M1 inhibited intracellular xanthine oxidase activity, one of the major sources of reactive oxygen species in vasculature, with an IC50 = 9.90 ± 0.01 μg/mL and reduced the expression of the inflammatory marker ICAM-1. These peculiar characteristics allow new perspectives to be opened up for the direct use of M1 instead of BBR in endothelial dysfunction treatment.
Grams, Lena; Kück, Momme; Haufe, Sven; Tegtbur, Uwe; Nelius, Anne-Katrin; Kerling, Arno
2017-05-01
Increasing physical activity is a cornerstone in the treatment of overweight individuals and self-selected exercise intensity leads to higher adherence to physical activity. However, information on differences in energy expenditure and fat oxidation between sexes regarding common self-paced activities of daily living are rare. We divided 33 subjects into normal weight (NW, N.=21) and overweight (OW, N.=12). Energy expenditure and substrate oxidation was measured during six self-paced physical activities of daily living using a portable spirometric system. We also determined maximum aerobic capacity (VO2max) and estimated free-living physical activity with a multi-sensor device. For all six activities, total energy expenditure was not different between NW and OW subjects in both sexes. The peak fat oxidation during physical activities was reached at higher intensities for women (NW 57±15%; OW 53±8% of VO2max) compared to men (NW 41±8%; OW 42±9% of VO2max) with no differences between NW and OW subjects. The majority of OW (92%) but not NW (42%) subjects reached their highest fat oxidation during walking. The self-selected walking speed was not significantly different between NW and OW men (NW 5.25±0.48 km/h, OW 5.52±0.42 km/h) and NW and OW women (NW 5.16±0.89 km/h, OW 5.01±0.42 km/h). When physical activity aims to maximizing fat oxidation, women should exercise at higher relative intensities than men, regardless of being normal weight or overweight. Self-paced walking is a suitable activity for overweight subjects to achieve high rates of both total energy expenditure and fat oxidation.
Sarasola-Puente, Vanessa; Gosá, Alberto; Oromí, Neus; Madeira, María José; Lizana, Miguel
2011-06-01
The mean age of a population of agile frogs (Rana dalmatina) from the Iberian Peninsula was estimated using mark and recapture and skeletochronology. Life-history parameters, including growth rate, body length, age and size at maturity, sexual dimorphism and longevity, were studied. The regression between age and snout-vent length (SVL) was highly significant in both sexes. Males reached sexual maturity at two years of age, although sometimes they can reach it at only one year of age. The average SVL at maturity was 51.75 mm (standard error (SE)=0.71; n=45). Females reached sexual maturity at two years of age with an average SVL of 62.14 mm (SE=2.20; n=14). A subset of the female population reached sexual maturity at three years of age. Growth was rapid until sexual maturity was reached. There was an overlap of SVL between different age classes. Growth was continuous, fulfilling the conditions of Von Bertalanffy's model. The growth coefficient (K) was 0.840 in males and 0.625 in females. The maximum SVL was greater in females (73.00 mm) than in males (59.50mm). Sexual dimorphism was significantly biased towards females in all age classes. The maximum longevity observed was 6 years in females and 8 years in males. Management strategies for agile frogs should take into account factors such as these life-history characteristics. Copyright © 2011 Elsevier GmbH. All rights reserved.
NASA Astrophysics Data System (ADS)
Warren, J.; Childs, J.; Ward, E. J.; Wullschleger, S.; Hanson, P. J.
2016-12-01
Since August 2015, the Spruce and Peatland Responses under Climatic and Environmental Change (SPRUCE) climate change experiment (http://mnspruce.ornl.gov/) in Northern Minnesota, USA, has exposed 13 m diameter plots of an ombrotrophic Picea mariana - Ericaceous shrub - Sphagnum bog ecosystem to long-term temperature (T) (0 to +9 °C) and since June 2016, elevated CO2 treatments (ambient or + 500 ppm). In addition to their direct impacts, the T and CO2 treatments have dramatically impacted soil water availability, vapor pressure deficit and # days dew point is reached. We examined plant water relations of Picea mariana (black spruce), Larix laricina (tamarack), and several Ericaceous shrubs including seasonal patterns of water potential (ψ), in addition to sap flow in the in trees. Granier-style thermal dissipation sensors were calibrated in situ (outside plots) by cutting instrumented trees and measuring their actual water uptake. Maximum summer T in N Minnesota reaches 35 °C, and optimal photosynthetic activity for P. mariana at the site peaks between 35-38°C. Treatments have resulted in air T reaching 45°C in the warmest plots resulting in substantial physiological stress. Pretreatment sap flow typically began by late May and was fairly constant over the season until declining in mid-September and ceasing as temperatures dropped below zero. Once the T treatments began, sap flow began earlier in the spring and continued later in the fall indicating an expanded physiological season that can result in plant vulnerability to extreme cold events. Indeed, foliar damage was evident in warmer plots following a spring freeze event in 2016. In addition, the drying heat has resulted in additional foliar damage, indicated by large reductions in predawn water potentials (even in the spring), quicker drying following rain events, and water stress reached earlier in the day. Midday mean summer ψ was -1.5 MPa for P. mariana foliage, higher than the co-occurring L. laricina (-2.0 MPa), but lower than shrubs (-1.1 MPa). Based on hydraulic measurements of excised tissue, P. mariana foliage remained higher that its turgor loss point (TLP), while midday L. laricina foliage often reached its TLP. Initial results indicate the potential for shifts in community composition due to differential heat and water stress among the species.
NASA Astrophysics Data System (ADS)
Lakeman, Thomas R.; England, John H.
2013-07-01
The study revises the maximum extent of the northwest Laurentide Ice Sheet (LIS) in the western Canadian Arctic Archipelago (CAA) during the last glaciation and documents subsequent ice sheet retreat and glacioisostatic adjustments across western Banks Island. New geomorphological mapping and maximum-limiting radiocarbon ages indicate that the northwest LIS inundated western Banks Island after ~ 31 14C ka BP and reached a terminal ice margin west of the present coastline. The onset of deglaciation and the age of the marine limit (22-40 m asl) are unresolved. Ice sheet retreat across western Banks Island was characterized by the withdrawal of a thin, cold-based ice margin that reached the central interior of the island by ~ 14 cal ka BP. The elevation of the marine limit is greater than previously recognized and consistent with greater glacioisostatic crustal unloading by a more expansive LIS. These results complement emerging bathymetric observations from the Arctic Ocean, which indicate glacial erosion during the Last Glacial Maximum (LGM) to depths of up to 450 m.
[Indoor simulation on dew formation on plant leaves].
Gao, Zhi-Yong; Wang, You-Ke; Wei, Xin-Guang; Liu, Shou-Yang; He, Zi-Li; Zhou, Yu-Hong
2014-03-01
Dew forming on plant leaves through water condensation plays a significant ecological role in arid and semi-arid areas as an ignorable fraction of water resources. In this study, an artificial intelligent climate chamber and an automatic temperature-control system for leaves were implemented to regulate the ambient temperature, the leaf surface temperature and the leaf inclination for dew formation. The impact of leaf inclination, ambient temperature and dew point-leaf temperature depression on the rate and quantity of dew accumulation on leaf surface were analyzed. The results indicated that the accumulation rate and the maximum volume of dew on leaves decreased with increasing the leaf inclination while increased with the increment of dew point-leaf temperature depression, ambient temperature and relative humidity. Under the horizontal configuration, dew accumulated linearly on leaf surface over time until the maximum volume (0.80 mm) was reached. However, dew would fall down after reaching the maximum volume when the leaf inclination existed (45 degrees or 90 degrees), significantly slowing down the accumulative rate, and the zigzag pattern for the dynamic of dew accumulation appeared.
NASA Astrophysics Data System (ADS)
Hattanji, T.; Wasklewicz, T.
2006-12-01
We examined geometry change of a steep first-order channel with a laserscanner before and after a small debris flow. The study site is located in chert area, Ashio Mountains, Japan. On August 12, 2005, a 20-year storm event with maximum 1-hour rainfall of 75.4 mm/h triggered a small landslide at a steep channel head. The sliding material moved as a debris flow along the first-order channel (C3) to the mouth. We successfully measured high-resolution channel topography with the Leica Geosystems High-Definition Surveying Laser Scanner before (April 30) and after the debris-flow event (October 9-11). Width, depth and other related parameters were measured for 30 selected cross sections. Bankfull stage of this first-order channel after the debris-flow event is much higher than two-year flood stage. The magnitude of channel geometry change varies non-linearly in downstream direction. The non-linear variability is attributed to differences in stream bed and bank characteristics. Bedrock-channel reach is less impacted by the debris flow. The largest magnitude changes in the channel geometry parameters occur along colluvially confined channel reaches.
Sabbioni, Enrico; Fortaner, Salvador; Farina, Massimo; Del Torchio, Riccardo; Petrarca, Claudia; Bernardini, Giovanni; Mariani-Costantini, Renato; Perconti, Silvia; Di Giampaolo, Luca; Gornati, Rosalba; Di Gioacchino, Mario
2014-02-01
The mechanistic understanding of nanotoxicity requires the physico-chemical characterisation of nanoparticles (NP), and their comparative investigation relative to the corresponding ions and microparticles (MP). Following this approach, the authors studied the dissolution, interaction with medium components, bioavailability in culture medium, uptake and intracellular distribution of radiolabelled Co forms (CoNP, CoMP and Co(2+)) in Balb/3T3 mouse fibroblasts. Co(2+) first saturates the binding sites of molecules in the extracellular milieu (e.g., albumin and histidine) and on the cell surface. Only after saturation, Co(2+) is actively uptaken. CoNP, instead, are predicted to be internalised by endocytosis. Dissolution of Co particles allows the formation of Co compounds (CoNP-rel), whose mechanism of cellular internalisation is unknown. Co uptake (ranking CoMP > CoNP > Co(2+)) reached maximum at 4 h. Once inside the cell, CoNP spread into the cytosol and organelles. Consequently, massive amounts of Co ions and CoNP-rel can reach subcellular compartments normally unexposed to Co(2+). This could explain the fact that the nuclear and mitochondrial Co concentrations resulted significantly higher than those obtained with Co(2+).
Irwin's conjecture: Crack shape adaptability in transversely isotropic solids
NASA Astrophysics Data System (ADS)
Laubie, Hadrien; Ulm, Franz-Josef
2014-08-01
The planar crack propagation problem of a flat elliptical crack embedded in a brittle elastic anisotropic solid is investigated. We introduce the concept of crack shape adaptability: the ability of three-dimensional planar cracks to shape with the mechanical properties of a cracked body. A criterion based on the principle of maximum dissipation is suggested in order to determine the most stable elliptical shape. This criterion is applied to the specific case of vertical cracks in transversely isotropic solids. It is shown that contrary to the isotropic case, the circular shape (i.e. penny-shaped cracks) is not the most stable one. Upon propagation, the crack first grows non-self-similarly before it reaches a stable shape. This stable shape can be approximated by an ellipse of an aspect ratio that varies with the degree of elastic anisotropy. By way of example, we apply the so-derived crack shape adaptability criterion to shale materials. For this class of materials it is shown that once the stable shape is reached, the crack propagates at a higher rate in the horizontal direction than in the vertical direction. We also comment on the possible implications of these findings for hydraulic fracturing operations.
Hou, Xiaohu; Ge, Xiangyang; Wu, Di; Qian, He; Zhang, Weiguo
2012-01-01
Brevibacterium flavum ATCC14067 was engineered for L: -valine production by overexpression of different ilv genes; the ilvEBN(r)C genes from B. flavum NV128 provided the best candidate for L: -valine production. In traditional fermentation, L: -valine production reached 30.08 ± 0.92 g/L at 31°C in 72 h with a low conversion efficiency of 0.129 g/g. To further improve the L: -valine production and conversion efficiency based on the optimum temperatures of L: -valine biosynthesis enzymes (above 35°C) and the thermotolerance of B. flavum, the fermentation temperature was increased to 34, 37, and 40°C. As a result, higher metabolic rate and L: -valine biosynthesis enzymes activity were obtained at high temperature, and the maximum L: -valine production, conversion efficiency, and specific L: -valine production rate reached 38.08 ± 1.32 g/L, 0.241 g/g, and 0.133 g g(-1) h(-1), respectively, at 37°C in 48 h fermentation. The strategy for enhancing L: -valine production by overexpression of key enzymes in thermotolerant strains may provide an alternative approach to enhance branched-chain amino acids production with other strains.
Catchment-wide survival of wild- and hatchery-reared Atlantic salmon smolts in a changing system
Stich, Daniel S.; Bailey, Michael M.; Holbrook, Christopher M.; Kinnison, Michael T.; Zydlewski, Joseph D.
2015-01-01
We developed a hierarchical multistate model to estimate survival of Atlantic salmon (Salmo salar) smolts in the Penobscot River, USA, over a decade during which two mainstem dams were removed from the catchment. We investigated effects of (i) environmental factors, (ii) rearing history, and (iii) management actions, including dam removal, turbine shutdown, and installation of new powerhouses. Mean ± SD smolt survival per kilometre was higher through free-flowing reaches of the catchment (0.995 ± 0.004·km−1) than through reaches containing dams that remain in the system (0.970 ± 0.019·km−1). We observed maximum survival between 12 and 17 °C and at intermediate discharges (1200 m3·s−1). Smolt survival increased concurrent with dam removal and decreased following increases in hydropower generation. The greatest increase in smolt survival followed seasonal turbine shutdowns at a dam located on the largest tributary to the Penobscot River, while other shutdowns had little influence. Our model provides a useful tool for assessing changes to survival of migratory species and will be useful for informing stocking plans to maximize numbers of smolts leaving coastal systems.
NASA Astrophysics Data System (ADS)
Dérerová, Jana; Kohút, Igor; Radwan, Anwar H.; Bielik, Miroslav
2017-12-01
The temperature model of the lithosphere along profile passing through the Red Sea region has been derived using 2D integrated geophysical modelling method. Using the extrapolation of failure criteria, lithology and calculated temperature distribution, we have constructed the rheological model of the lithosphere in the area. We have calculated the strength distribution in the lithosphere and constructed the strength envelopes for both compressional and extensional regimes. The obtained results indicate that the strength steadily decreases from the Western desert through the Eastern desert towards the Red Sea where it reaches its minimum for both compressional and extensional regime. Maximum strength can be observed in the Western desert where the largest strength reaches values of about 250-300 MPa within the upper crust on the boundary between upper and lower crust. In the Eastern desert we observe slightly decreased strength with max values about 200-250 MPa within upper crust within 15 km with compression being dominant. These results suggest mostly rigid deformation in the region or Western and Eastern desert. In the Red Sea, the strength rapidly decreases to its minimum suggesting ductile processes as a result of higher temperatures.
Enhanced performance of ZnO microballoon arrays for a triboelectric nanogenerator.
Deng, Weili; Zhang, Binbin; Jin, Long; Chen, Yueqi; Chu, Wenjun; Zhang, Haitao; Zhu, Minhao; Yang, Weiqing
2017-03-01
In recent years, triboelectric nanogenerators (TENGs), harvesting energy from the environment as a sustainable power source, have attracted great attention. Currently, many reports focus on the effect of surface modification on the electrical output performance of the TENG. In this work, we have fabricated vertically grown ZnO microballoon (ZnOMB) arrays on top of pyramid-featured PDMS patterned film, contacted with PTFE film to construct the TENG. The electrical output performances of the designed TENG are presented under external forces with different frequencies. The corresponding output open-circuit voltage with ZnOMBs could reach about 57 V the current density about 59 mA m -2 at 100 Hz, which was about 2.3 times higher than without any ZnO. The global maximum of the instantaneous peak power could reach 1.1 W m -2 when the external load resistance was about 2 MΩ. Furthermore, the electrical output of the fabricated device could light 30 commercial LED bulbs without any rectifier circuits or energy-storage elements. This clearly suggests that this kind of surface modification can dramatically enhance the output performance of the TENG. Moreover, the design of TENG demonstrated here can be applied to various energy harvesting applications.
Enhanced performance of ZnO microballoon arrays for a triboelectric nanogenerator
NASA Astrophysics Data System (ADS)
Deng, Weili; Zhang, Binbin; Jin, Long; Chen, Yueqi; Chu, Wenjun; Zhang, Haitao; Zhu, Minhao; Yang, Weiqing
2017-03-01
In recent years, triboelectric nanogenerators (TENGs), harvesting energy from the environment as a sustainable power source, have attracted great attention. Currently, many reports focus on the effect of surface modification on the electrical output performance of the TENG. In this work, we have fabricated vertically grown ZnO microballoon (ZnOMB) arrays on top of pyramid-featured PDMS patterned film, contacted with PTFE film to construct the TENG. The electrical output performances of the designed TENG are presented under external forces with different frequencies. The corresponding output open-circuit voltage with ZnOMBs could reach about 57 V the current density about 59 mA m-2 at 100 Hz, which was about 2.3 times higher than without any ZnO. The global maximum of the instantaneous peak power could reach 1.1 W m-2 when the external load resistance was about 2 MΩ. Furthermore, the electrical output of the fabricated device could light 30 commercial LED bulbs without any rectifier circuits or energy-storage elements. This clearly suggests that this kind of surface modification can dramatically enhance the output performance of the TENG. Moreover, the design of TENG demonstrated here can be applied to various energy harvesting applications.
Cruz Jentoft, A J; Hernández, B
2014-01-01
Alzheimer disease (AD) causes progressive cognitive decline leading to loss of independence for activities of daily living; rivastigmine is one of the drugs used for symptomatic management. To assess the therapeutic use of different pharmaceutical forms of rivastigmine in patients with AD in normal clinical practice. Cross-sectional, observational, multi-centre study conducted on patients with mild to moderate AD treated with rivastigmine in Spanish outpatient clinics specialising in Geriatrics, Psychiatry, and Neurology. Data regarding use of oral (OR) and transdermal (TDR) rivastigmine, compliance (degree of adherence), and caregiver satisfaction with treatment were evaluated. In total, 2252 patients with a mean age of 77.2 years were included; 60.2% were women. AD was moderate to moderately severe in 58.4%. Rivastigmine treatment was started orally in 54.4% of the patients and transdermally in 45.6%; 35.6% of those who started treatment by the OR route switched to TDR. A single dose adjustment was sufficient for 77.5% of patients on TDR treatment vs 11.8% of patients receiving OR treatment. More patients on TDR treatment (80.8% vs. 57.1% on OR treatment) reached the maximum therapeutic dose of rivastigmine and did so in a shorter period of time (51.6 vs 205.8 days). Compliance rates (60.5% vs 47.2%) and caregivers' satisfaction with treatment (89.4% vs 81.9%) were also higher for TDR. In normal clinical practice, using the TDR route of administration improves dose titration and drug compliance, allowing more patients to reach the maximum recommended dose of rivastigmine in a shorter time period. Copyright © 2012 Sociedad Española de Neurología. Published by Elsevier Espana. All rights reserved.
The different baryonic Tully-Fisher relations at low masses.
Brook, Chris B; Santos-Santos, Isabel; Stinson, Greg
2016-06-11
We compare the Baryonic Tully-Fisher relation (BTFR) of simulations and observations of galaxies ranging from dwarfs to spirals, using various measures of rotational velocity V rot . We explore the BTFR when measuring V rot at the flat part of the rotation curve, V flat , at the extent of H i gas, V last , and using 20 per cent ( W 20 ) and 50 per cent ( W 50 ) of the width of H i line profiles. We also compare with the maximum circular velocity of the parent halo, [Formula: see text], within dark matter only simulations. The different BTFRs increasingly diverge as galaxy mass decreases. Using V last one obtains a power law over four orders of magnitude in baryonic mass, with slope similar to the observed BTFR. Measuring V flat gives similar results as V last when galaxies with rising rotation curves are excluded. However, higher rotation velocities would be found for low-mass galaxies if the cold gas extended far enough for V rot to reach a maximum. W 20 gives a similar slope as V last but with slightly lower values of V rot for low-mass galaxies, although this may depend on the extent of the gas in your galaxy sample. W 50 bends away from these other relations towards low velocities at low masses. By contrast, [Formula: see text] bends towards high velocities for low-mass galaxies, as cold gas does not extend out to the radius at which haloes reach [Formula: see text]. Our study highlights the need for careful comparisons between observations and models: one needs to be consistent about the particular method of measuring V rot , and precise about the radius at which velocities are measured.
Wang, Lunche; Gong, Wei; Lin, Aiwen; Hu, Bo
2014-10-01
Observations of photosynthetically active radiation (PAR) and global solar radiation (G) at Wuhan, Central China during 2005-2012 were first reported to investigate PAR variability at different time scales and its PAR fraction (F(p)) under different sky conditions. Both G irradiances (I(g)) and PAR irradiances (I(p)) showed similar seasonal features that peaked in values at noon during summer and reached their lower values in winter. F(p) reached higher values during either sunrise or sunset; lower values of F p appeared at local noon because of the absorption effects of water vapor and clouds on long-wave radiation. There was an inverse relationship between clearness index (K(t)) and F(p); the maximum I(p) decreased by 22.3 % (39.7 %) when sky conditions changed from overcast to cloudless in summer (winter); solar radiation was more affected by cloudiness than the seasonal variation in cloudy skies when compared with that in clear skies. The maximum daily PAR irradiation (R(p)) was 11.89 MJ m⁻² day⁻¹ with an annual average of 4.85 MJ m⁻² day⁻¹. F p was in the range of 29-61.5 % with annual daily average value being about 42 %. Meanwhile, hourly, daily, and monthly relationships between R p and G irradiation (R g) under different sky conditions were investigated. It was discovered that cloudy skies were the dominated sky condition in this region. Finally, a clear-sky PAR model was developed by analyzing the dependence of PAR irradiances on optical air mass under various sky conditions for the whole study period in Central China, which will lay foundations for ecological process study in the near future.
Peat and coconut fiber as biofilters for chromium adsorption from contaminated wastewaters.
Henryk, Kołoczek; Jarosław, Chwastowski; Witold, Żukowski
2016-01-01
Batch adsorption experiments were performed for the removal of chromium (III) and chromium (VI) ions from aqueous solutions using Canadian peat and coconut fiber. The Langmuir model was used to describe the adsorption isotherm. The maximum adsorption for peat reached 18.75 mg/g for Cr(III) and 8.02 mg/g for Cr(VI), whereas the value for fiber was slightly higher and reached 19.21 mg/g for Cr(III) and 9.54 mg/g for Cr(VI). Both chromium forms could be easily eluted from the materials. The adsorption of chromium forms to organic matter could be explained in terms of formation of donor-acceptor chemical covalent bound with hydroxyl groups as ligands and chromium as the central atom in the formed complex. The chromate-reducing activities were monitored with the use of electron paramagnetic resonance spectroscopy. The results showed that both adsorption and reduction occurred simultaneously and the maximum adsorption capacity of hexavalent chromium being equal to 95% for fiber and 92% for peat was obtained at pH 1.5. The reduction of Cr(VI) in wastewaters began immediately and disappeared after 20 h. Both materials contained yeast and fungi species which can be responsible for reduction of chromium compounds, due to their enzymatic activity (Chwastowski and Koloczek (Acta Biochim Pol 60: 829-834, 2013)). The reduction of Cr(VI) is a two-phase process, the first phase being rapid and based on chemical reaction and the second phase having biological features. After the recovery step, both types of organic materials can be used again for chromium adsorption without any loss in the metal uptake. Both of the materials could be used as biofilters in the wastewater treatment plants.
NASA Astrophysics Data System (ADS)
Cheriton, Olivia M.; Storlazzi, Curt D.; Rosenberger, Kurt J.
2016-05-01
Many low-lying tropical islands are susceptible to sea level rise and often subjected to overwash and flooding during large wave events. To quantify wave dynamics and wave-driven water levels on fringing coral reefs, a 5 month deployment of wave gauges and a current meter was conducted across two shore-normal transects on Roi-Namur Island in the Republic of the Marshall Islands. These observations captured two large wave events that had waves with maximum heights greater than 6 m with peak periods of 16 s over the fore reef. The larger event coincided with a peak spring tide, leading to energetic, highly skewed infragravity (0.04-0.004 Hz) and very low frequency (0.004-0.001 Hz) waves at the shoreline, which reached heights of 1.0 and 0.7 m, respectively. Water surface elevations, combined with wave runup, reached 3.7 m above the reef bed at the innermost reef flat adjacent to the toe of the beach, resulting in flooding of inland areas. This overwash occurred during a 3 h time window that coincided with high tide and maximum low-frequency reef flat wave heights. The relatively low-relief characteristics of this narrow reef flat may further drive shoreline amplification of low-frequency waves due to resonance modes. These results (1) demonstrate how the coupling of high offshore water levels with low-frequency reef flat wave energetics can lead to large impacts along fringing reef-lined shorelines, such as island overwash, and (2) lend support to the hypothesis that predicted higher sea levels will lead to more frequent occurrences of these extreme events, negatively impacting coastal resources and infrastructure.
Cheriton, Olivia; Storlazzi, Curt; Rosenberger, Kurt
2016-01-01
Many low-lying tropical islands are susceptible to sea level rise and often subjected to overwash and flooding during large wave events. To quantify wave dynamics and wave-driven water levels on fringing coral reefs, a 5 month deployment of wave gauges and a current meter was conducted across two shore-normal transects on Roi-Namur Island in the Republic of the Marshall Islands. These observations captured two large wave events that had waves with maximum heights greater than 6 m with peak periods of 16 s over the fore reef. The larger event coincided with a peak spring tide, leading to energetic, highly skewed infragravity (0.04–0.004 Hz) and very low frequency (0.004–0.001 Hz) waves at the shoreline, which reached heights of 1.0 and 0.7 m, respectively. Water surface elevations, combined with wave runup, reached 3.7 m above the reef bed at the innermost reef flat adjacent to the toe of the beach, resulting in flooding of inland areas. This overwash occurred during a 3 h time window that coincided with high tide and maximum low-frequency reef flat wave heights. The relatively low-relief characteristics of this narrow reef flat may further drive shoreline amplification of low-frequency waves due to resonance modes. These results (1) demonstrate how the coupling of high offshore water levels with low-frequency reef flat wave energetics can lead to large impacts along fringing reef-lined shorelines, such as island overwash, and (2) lend support to the hypothesis that predicted higher sea levels will lead to more frequent occurrences of these extreme events, negatively impacting coastal resources and infrastructure.
Directional power absorption in helicon plasma sources excited by a half-helix antenna
NASA Astrophysics Data System (ADS)
Afsharmanesh, Mohsen; Habibi, Morteza
2017-10-01
This paper deals with the investigation of the power absorption in helicon plasma excited through a half-helix antenna driven at 13.56 {{MHz}}. The simulations were carried out by means of a code, HELIC. They were carried out by taking into account different inhomogeneous radial density profiles and for a wide range of plasma densities, from {10}11 {{{cm}}}-3 to {10}13 {{{cm}}}-3. The magnetic field was 200, 400, 600 and 1000 {{G}}. A three-parameter function was used for generating various density profiles with different volume gradients, edge gradients and density widths. The density profile had a large effect on the efficient Trivelpiece-Gould (TG) and helicon mode excitation and antenna coupling to the plasma. The fraction of power deposition via the TG mode was extremely dependent on the plasma density near the plasma boundary. Interestingly, the obtained efficient parallel helicon wavelength was close to the anticipated value for Gaussian radial density profile. Power deposition was considerably asymmetric when the \\tfrac{n}{{B}0} ratio was more than a specific value for a determined density width. The longitudinal power absorption was symmetric at approximately {n}0={10}11 {{{cm}}}-3, irrespective of the magnetic field supposed. The asymmetry became more pronounced when the plasma density was {10}12 {{{cm}}}-3. The ratio of density width to the magnetic field was an important parameter in the power coupling. At high magnetic fields, the maximum of the power absorption was reached at higher plasma density widths. There was at least one combination of the plasma density, magnetic field and density width for which the RF power deposition at both side of the tube reached its maximum value.
Trichoderma harzianum elicits induced resistance in sunflower challenged by Rhizoctonia solani.
Singh, B N; Singh, A; Singh, B R; Singh, H B
2014-03-01
To investigate the efficacy of Trichoderma harzianum NBRI-1055 (denoted as 'T-1055') in suppression of seedling blight of sunflower caused by Rhizoctonia solani Kühn and their impact on host defence responses. T-1055 was applied as seed treatment, soil application and combined application (seed treatment + soil application). Higher protection afforded by combined application of T-1055 was associated with the marked induction of phenylalanine ammonia-lyase (PAL), polyphenol oxidase (PPO), peroxidase (PO) and cinnamyl alcohol dehydrogenase (CAD) activities. The activities of PAL and PPO reached maximum at 10 days after sowing (DAS), while PO and CAD levels reached maximum at 12 DAS. This was further supported by the accumulation of total phenolic content that showed an increase up to threefold at 14 DAS. In addition, HPLC analysis revealed that the contents of ferulic and p-coumaric acids increased by 6·3 and 4·6 times, respectively, at 14 DAS. Amount of gallic acid was also little more than double. Lignin deposition in sunflower root increased by 2·7, 3·4 and 3·7 times through combined application of T-1055 at 16, 18 and 20 DAS, respectively. Combined application also increased the accumulation of PR-2 and PR-3 proteins by 3·3 and 3·9 times, respectively, at 12 DAS in followed by seed treatment alone. The combined application of T-1055 triggered defence responses in an enhanced level in sunflower than the soil and seed alone and provided better protection against Rhizoctonia seedling blight. Rhizospheric fungal bioagent 'T-1055' can enhance protection in sunflower against the R. solani pathogen through augmented elicitation of host defence responses. © 2013 The Society for Applied Microbiology.
Peng, Lixin; Chen, De; Setlow, Peter; Li, Yong-qing
2009-01-01
Raman scattering spectroscopy and elastic light scattering intensity (ESLI) were used to simultaneously measure levels of Ca-dipicolinic acid (CaDPA) and changes in spore morphology and refractive index during germination of individual B. subtilis spores with and without the two redundant enzymes (CLEs), CwlJ and SleB, that degrade spores’ peptidoglycan cortex. Conclusions from these measurements include: 1) CaDPA release from individual wild-type germinating spores was biphasic; in a first heterogeneous slow phase, Tlag, CaDPA levels decreased ∼15% and in the second phase ending at Trelease, remaining CaDPA was released rapidly; 2) in L-alanine germination of wild-type spores and spores lacking SleB: a) the ESLI rose ∼2-fold shortly before Tlag at T1; b) following Tlag, the ESLI again rose ∼2-fold at T2 when CaDPA levels had decreased ∼50%; and c) the ESLI reached its maximum value at ∼Trelease and then decreased; 3) in CaDPA germination of wild-type spores: a) Tlag increased and the first increase in ESLI occurred well before Tlag, consistent with different pathways for CaDPA and L-alanine germination; b) at Trelease the ESLI again reached its maximum value; 4) in L-alanine germination of spores lacking both CLEs and unable to degrade their cortex, the time ΔTrelease (Trelease–Tlag) for excretion of ≥75% of CaDPA was ∼15-fold higher than that for wild-type or sleB spores; and 5) spores lacking only CwlJ exhibited a similar, but not identical ESLI pattern during L-alanine germination to that seen with cwlJ sleB spores, and the high value for ΔTrelease. PMID:19374431
Reaction time in pilots during intervals of high sustained g.
Truszczynski, Olaf; Lewkowicz, Rafal; Wojtkowiak, Mieczyslaw; Biernacki, Marcin P
2014-11-01
An important problem for pilots is visual disturbances occurring under +Gz acceleration. Assessment of the degree of intensification of these disturbances is generally accepted as the acceleration tolerance level (ATL) criterion determined in human centrifuges. The aim of this research was to evaluate the visual-motor responses of pilots during rapidly increasing acceleration contained in cyclic intervals of +6 Gz to the maximum ATL. The study involved 40 male pilots ages 32-41 yr. The task was a quick and faultless response to the light stimuli presented on a light bar during exposure to acceleration until reaching the ATL. Simple response time (SRT) measurements were performed using a visual-motor analysis system throughout the exposures which allowed assessment of a pilot's ATL. There were 29 pilots who tolerated the initial phase of interval acceleration and achieved +6 Gz, completing the test at ATL. Relative to the control measurements, the obtained results indicate a significant effect of the applied acceleration on response time. SRT during +6 Gz exposure was not significantly longer compared with the reaction time between each of the intervals. SRT and erroneous reactions indicated no statistically significant differences between the "lower" and "higher" ATL groups. SRT measurements over the +6-Gz exposure intervals did not vary between "lower" and "higher" ATL groups and, therefore, are not useful in predicting pilot performance. The gradual exposure to the maximum value of +6 Gz with exposure to the first three intervals on the +6-Gz plateau effectively differentiated pilots.
Tunnel magnetoresistance in ultrathin L10 MnGa/MgO perpendicular magnetic tunnel junctions
NASA Astrophysics Data System (ADS)
Suzuki, K. Z.; Miura, Y.; Ranjbar, R.; Sugihara, A.; Mizukami, S.
2018-06-01
L10 MnGa is one of the interesting magnetic alloys for spin-transfer-torque based applications because such alloys have high perpendicular magnetic anisotropy, small magnetization, and low Gilbert damping. Magnetic tunnel junctions (MTJs) with ultrathin MnGa electrodes have recently been demonstrated using the room temperature growth technique of MnGa on paramagnetic B2-ordered CoGa templates, which exhibited a small TMR ratio of ∼3%. To obtain a higher TMR ratio, we systematically investigated the annealing dependence of the TMR ratio with MTJs with 1–5 nm thick MnGa electrodes in this study. The TMR ratios were 2%–3% without annealing, which were the same as those reported previously, and the TMR ratios reached their maximum values of 6%–8% at an annealing temperature of approximately 250 °C for the MTJs with 2–5 nm MnGa electrodes. The TMR ratio increased to approximately 25% at 10 K for those MTJs. These TMR ratios were slightly higher than those reported in MTJs with 30 nm-thick MnGa electrodes. The annealing temperature at which TMR showed the maximum value tended to decrease with decreasing MnGa thickness, and this low annealing endurance may be attributed to the atomic mixing between MnGa and barrier/buffer layers. The TMR ratio was discussed in terms of both coherent tunneling based on first principles calculations with different element terminations at the interface and incoherent tunneling.
NASA Astrophysics Data System (ADS)
Trifonova, T. A.; Zabelina, O. N.
2017-04-01
Urban recreation areas of different sizes were investigated in the city of Vladimir. The degree of their contamination with heavy metals and oil products was revealed. The content of heavy metals exceeded their maximum permissible concentrations by more than 2.5 times. The total content of heavy metals decreased in the sequence: Zn > Pb > Co > Mn > Cr > Ni. The mass fraction of oil products in the studied soils varied within the range of 0.016-0.28 mg/g. The reaction of soils in public gardens and a boulevard was neutral or close to neutral; in some soil samples, it was weakly alkaline. The top layer of all the soils significantly differed from the lower one by the higher alkalinity promoting the deposition of heavy metals there. As the content of Ni, Co, and Mn increased and exceeded the background concentrations, but did not reach the three-fold value of the maximum permissible concentrations, the activity of catalase was intensified. The stimulating effect of nickel on the catalase activity was mostly pronounced at the neutral soil reaction. The urease activity increased when heavy metals and oil products were present together in the concentrations above the background ones, but not higher than the three-fold maximal permissible concentrations for heavy metals and 0.3 mg/g for the content of oil products. The nitrifying activity was inhibited by oil hydrocarbons that were recorded in the soils in different amounts.
Verdini, Federica; Zara, Claudio; Leo, Tommaso; Mengarelli, Alessandro; Cardarelli, Stefano; Innocenti, Bernardo
2017-01-01
Summary Background In this paper, squat named by Authors unconstrained because performed without constrains related to feet position, speed, knee maximum angle to be reached, was tested as motor task revealing differences in functional performance after knee arthroplasty. It involves large joints ranges of motion, does not compromise joint safety and requires accurate control strategies to maintain balance. Methods Motion capture techniques were used to study squat on a healthy control group (CTR) and on three groups, each characterised by a specific knee arthroplasty design: a Total Knee Arthroplasty (TKA), a Mobile Bearing and a Fixed Bearing Unicompartmental Knee Arthroplasty (respectively MBUA and FBUA). Squat was analysed during descent, maintenance and ascent phase and described by speed, angular kinematics of lower and upper body, the Center of Pressure (CoP) trajectory and muscle activation timing of quadriceps and biceps femoris. Results Compared to CTR, for TKA and MBUA knee maximum flexion was lower, vertical speed during descent and ascent reduced and the duration of whole movement was longer. CoP mean distance was higher for all arthroplasty groups during descent as higher was, CoP mean velocity for MBUA and TKA during ascent and descent. Conclusions Unconstrained squat is able to reveal differences in the functional performance among control and arthroplasty groups and between different arthroplasty designs. Considering the similarity index calculated for the variables showing statistically significance, FBUA performance appears to be closest to that of the CTR group. Level of evidence III a. PMID:29387646
Raina, Renata; Hall, Patricia; Sun, Lina
2010-11-15
This paper presents the atmospheric occurrence and seasonal variations of the most frequently detected organophosphorus insecticides (OPs) and their OP oxon degradation products at Bratt's Lake, Saskatchewan in the Canadian Prairies (April 2003 to March 2004, January-December, 2005) and at Abbotsford in the Lower Frazer Valley (LFV) of British Columbia from May 2004 to December, 2005. During 2005 there were 10 OPs, 8 OP oxons, and 6 other OP degradation products measured. The most frequently detected OPs were chlorpyrifos, malathion, and diazinon. At Bratt's Lake the highest atmospheric concentrations were observed for chlorpyrifos, with maximum concentrations observed during July and August in 2003 showing much higher concentrations than those from 2005. This was related to its usage for grasshopper control in the province. At Abbotsford, diazinon and malathion were observed in much higher atmospheric concentrations than chlorpyrifos. Concentrations reached maximum in spring for diazinon and summer for malathion. This study is the first reported study of seasonal variations of OP oxons with their parent OP. Chlorpyrifos oxon concentrations during July were generally low, indicating strong local source contributions. The chlorpyrifos oxon/chlorpyrifos ratio and diazinon oxon/diazinon ratio showed a strong seasonal variation with increasing ratio from spring to summer which was attributed to increasing sunlight hours. Malathion oxon/mathion at both sites was similar and relatively constant throughout the year. The oxon/thion ratio represents a good indicator of age of source or contributions from local versus regional atmospheric sources.
Wagner, G N; Kuchel, L J; Lotto, A; Patterson, D A; Shrimpton, J M; Hinch, S G; Farrell, A P
2006-01-01
We present the first data on the differences in routine and active metabolic rates for sexually maturing migratory adult sockeye salmon (Oncorhynchus nerka) that were intercepted in the ocean and then held in either seawater or freshwater. Routine and active oxygen uptake rates (MO2) were significantly higher (27%-72%) in seawater than in freshwater at all swimming speeds except those approaching critical swimming speed. During a 45-min recovery period, the declining postexercise oxygen uptake remained 58%-73% higher in seawater than in freshwater. When fish performed a second swim test, active metabolic rates again remained 28%-81% higher for fish in seawater except at the critical swimming speed. Despite their differences in metabolic rates, fish in both seawater and freshwater could repeat the swim test and reach a similar maximum oxygen uptake and critical swimming speed as in the first swim test, even without restoring routine metabolic rate between swim tests. Thus, elevated MO2 related to either being in seawater as opposed to freshwater or not being fully recovered from previous exhaustive exercise did not present itself as a metabolic loading that limited either critical swimming performance or maximum MO2. The basis for the difference in metabolic rates of migratory sockeye salmon held in seawater and freshwater is uncertain, but it could include differences in states of nutrition, reproduction, and restlessness, as well as ionic differences. Regardless, this study elucidates some of the metabolic costs involved during the migration of adult salmon from seawater to freshwater, which may have applications for fisheries conservation and management models of energy use.
Jin, Yu; Teng, Chunying; Yu, Sumei; Song, Tao; Dong, Liying; Liang, Jinsong; Bai, Xin; Liu, Xuesheng; Hu, Xiaojing; Qu, Juanjuan
2018-01-01
To prevent the blockage in a continuous fix-bed system, Pleurotus Ostreatus spent substrate (POSS), a composite agricultural waste, was immobilized into granular adsorbents (IPOSS) with polymeric matrix, and used to remove Cd(II) from synthetic wastewater in batch experiment as well as in continuous fixed-bed column system. In batch experiment, higher pH, temperature and Cd(II) initial concentration were conducive to a higher biosorption capacity, and the maximum biosorption capacity reached up to 87.2 mg/g at Cd(II) initial concentration of 200 mg/L, pH 6 and 25 °C. The biosorption of Cd(II) onto IPOSS followed the Langmuir isotherm model with the maximum adsorption capacity(q max ) of 100 mg/g. The biosorption was an endothermic reaction and a spontaneous process based on positive value of ΔH 0 and negative value of ΔG 0 . In fixed-bed column system, higher bed depth, lower flow rate and influent Cd(II) concentration led to a longer breakthrough and exhaustion time, and the best performance (equilibrium uptake (q e ) of 14.4 mg, breakthrough time at 31 h and exhaustion time at 78 h) was achieved at a bed depth of 110 cm, a flow rate of 1.2 L/h and an influent concentration of 100 mg/L. Furthermore, regeneration experiment revealed a good reusability of IPOSS with 0.1 M HNO 3 as eluting agent during three cycles of adsorption and desorption. Cd(II) biosorption onto IPOSS mainly relied on a chemical process including ion exchange and complexation or coordination revealed by SEM-EDX, FTIR and XRD analysis. Copyright © 2017. Published by Elsevier Ltd.
Maximum of a Fractional Brownian Motion: Analytic Results from Perturbation Theory.
Delorme, Mathieu; Wiese, Kay Jörg
2015-11-20
Fractional Brownian motion is a non-Markovian Gaussian process X_{t}, indexed by the Hurst exponent H. It generalizes standard Brownian motion (corresponding to H=1/2). We study the probability distribution of the maximum m of the process and the time t_{max} at which the maximum is reached. They are encoded in a path integral, which we evaluate perturbatively around a Brownian, setting H=1/2+ϵ. This allows us to derive analytic results beyond the scaling exponents. Extensive numerical simulations for different values of H test these analytical predictions and show excellent agreement, even for large ϵ.
Field-deployable gamma-radiation detectors for DHS use
NASA Astrophysics Data System (ADS)
Mukhopadhyay, Sanjoy
2007-09-01
Recently, the Department of Homeland Security (DHS) has integrated all nuclear detection research, development, testing, evaluation, acquisition, and operational support into a single office: the Domestic Nuclear Detection Office (DNDO). The DNDO has specific requirements set for all commercial off-the-shelf and government off-the-shelf radiation detection equipment and data acquisition systems. This article would investigate several recent developments in field deployable gamma radiation detectors that are attempting to meet the DNDO specifications. Commercially available, transportable, handheld radio isotope identification devices (RIID) are inadequate for DHS' requirements in terms of sensitivity, resolution, response time, and reach-back capability. The leading commercial vendor manufacturing handheld gamma spectrometer in the United States is Thermo Electron Corporation. Thermo Electron's identiFINDER TM, which primarily uses sodium iodide crystals (3.18 x 2.54cm cylinders) as gamma detectors, has a Full-Width-at-Half-Maximum energy resolution of 7 percent at 662 keV. Thermo Electron has just recently come up with a reach-back capability patented as RadReachBack TM that enables emergency personnel to obtain real-time technical analysis of radiation samples they find in the field1. The current project has the goal to build a prototype handheld gamma spectrometer, equipped with a digital camera and an embedded cell phone to be used as an RIID with higher sensitivity, better resolution, and faster response time (able to detect the presence of gamma-emitting radio isotopes within 5 seconds of approach), which will make it useful as a field deployable tool. The handheld equipment continuously monitors the ambient gamma radiation, and, if it comes across any radiation anomalies with higher than normal gamma gross counts, it sets an alarm condition. When a substantial alarm level is reached, the system automatically triggers the saving of relevant spectral data and software-triggers the digital camera to take a snapshot. The spectral data including in situ analysis and the imagery data will be packaged in a suitable format and sent to a command post using an imbedded cell phone.
Stochastic Background from Coalescences of Neutron Star-Neutron Star Binaries
NASA Astrophysics Data System (ADS)
Regimbau, T.; de Freitas Pacheco, J. A.
2006-05-01
In this work, numerical simulations were used to investigate the gravitational stochastic background produced by coalescences of double neutron star systems occurring up to z~5. The cosmic coalescence rate was derived from Monte Carlo methods using the probability distributions for massive binaries to form and for a coalescence to occur in a given redshift. A truly continuous background is produced by events located only beyond the critical redshift z*=0.23. Events occurring in the redshift interval 0.027
NASA Astrophysics Data System (ADS)
Chen, Xiaotao; Song, Jie; Liang, Lixiao; Si, Yang; Wang, Le; Xue, Xiaodai
2017-10-01
Large-scale energy storage system (ESS) plays an important role in the planning and operation of smart grid and energy internet. Compressed air energy storage (CAES) is one of promising large-scale energy storage techniques. However, the high cost of the storage of compressed air and the low capacity remain to be solved. This paper proposes a novel non-supplementary fired compressed air energy storage system (NSF-CAES) based on salt cavern air storage to address the issues of air storage and the efficiency of CAES. Operating mechanisms of the proposed NSF-CAES are analysed based on thermodynamics principle. Key factors which has impact on the system storage efficiency are thoroughly explored. The energy storage efficiency of the proposed NSF-CAES system can be improved by reducing the maximum working pressure of the salt cavern and improving inlet air pressure of the turbine. Simulation results show that the electric-to-electric conversion efficiency of the proposed NSF-CAES can reach 63.29% with a maximum salt cavern working pressure of 9.5 MPa and 9 MPa inlet air pressure of the turbine, which is higher than the current commercial CAES plants.
Sensitivity of the Palaeocene-Eocene Thermal Maximum climate to cloud properties.
Kiehl, Jeffrey T; Shields, Christine A
2013-10-28
The Palaeocene-Eocene Thermal Maximum (PETM) was a significant global warming event in the Earth's history (approx. 55 Ma). The cause for this warming event has been linked to increases in greenhouse gases, specifically carbon dioxide and methane. This rapid warming took place in the presence of the existing Early Eocene warm climate. Given that projected business-as-usual levels of atmospheric carbon dioxide reach concentrations of 800-1100 ppmv by 2100, it is of interest to study past climates where atmospheric carbon dioxide was higher than present. This is especially the case given the difficulty of climate models in simulating past warm climates. This study explores the sensitivity of the simulated pre-PETM and PETM periods to change in cloud condensation nuclei (CCN) and microphysical properties of liquid water clouds. Assuming lower levels of CCN for both of these periods leads to significant warming, especially at high latitudes. The study indicates that past differences in cloud properties may be an important factor in accurately simulating past warm climates. Importantly, additional shortwave warming from such a mechanism would imply lower required atmospheric CO2 concentrations for simulated surface temperatures to be in reasonable agreement with proxy data for the Eocene.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Uhoya, Walter; Tsoi, Georgiy; Vohra, Yogesh
Simultaneous high-pressure X-ray diffraction and electrical resistance measurements have been carried out on a PbO-type {alpha}-FeSe{sub 0.92} compound to a pressure of 44 GPa and temperatures down to 4 K using designer diamond anvils at synchrotron source. A ambient temperature, a structural phase transition from a tetragonal (P4/nmm) phase to an orthorhombic (Pbnm) phase is observed at 11 GPa and the Pbnm phase persists up to 74 GPa. The superconducting transition temperature (T{sub c}) increases rapidly with pressure reaching a maximum of {approx}28 K at {approx}6 GPa and decreases at higher pressures, disappearing completely at 14.6 GPa. Simultaneous pressure-dependent X-raymore » diffraction and resistance measurements at low temperatures show superconductivity only in a low-pressure orthorhombic (Cmma) phase of the {alpha}-FeSe{sub 0.92}. Upon increasing pressure at 10 K near T{sub c}, crystalline phases change from a mixture of orthorhombic (Cmma) and hexagonal (P63/mmc) phases to a high-pressure orthorhombic (Pbnm) phase near 6.4 GPa where T{sub c} is maximum.« less
Dogrul, Ahmet; Arslan, Seyda Akkus; Tirnaksiz, Figen
2014-01-01
The purpose of this study was to develop a water/oil microemulsion containing lidocaine hydrochloride (4%) and to compare its local anaesthetic efficacy with commercial products. A pseudoternary diagram (Km:1/1 or 1/2) was constructed using lecithin/ethanol/oil/water. The droplet size, viscosity and release of the microemulsions were evaluated. Tail flick tests were conducted for in vivo effectiveness; the initiation time of effect, maximum effect, time to reach maximum effect, and relative efficacy were evaluated. The drug caused a significant increase in droplet size. The use of olive oil resulted in a decrease in the solubilisation parameter, as well as a reduction in the release. The droplet size and viscosity of the microemulsion composed of Miglyol/lecithin/ethanol/water/drug (Km:1/2) was lower than other microemulsions (8.38 nm, 6.9 mPa), and its release rate (1.61 mg/h) was higher. This system had a faster and more efficient anaesthetic effect than the other microemulsions and commercial products. Results indicate that a water/oil type microemulsion (Miglyol/lecithin/ethanol/water) has promising potential to increase the local anaesthetic effect.
Improving carbon dioxide yields and cell efficiencies for ethanol oxidation by potential scanning
NASA Astrophysics Data System (ADS)
Majidi, Pasha; Pickup, Peter G.
2014-12-01
An ethanol electrolysis cell with aqueous ethanol supplied to the anode and nitrogen at the cathode has been operated under potential cycling conditions in order to increase the yield of carbon dioxide and thereby increase cell efficiency relative to operation at a fixed potential. At ambient temperature, faradaic yields of CO2 as high as 26% have been achieved, while only transient CO2 production was observed at constant potential. Yields increased substantially at higher temperatures, with maximum values at Pt anodes reaching 45% at constant potential and 65% under potential cycling conditions. Use of a PtRu anode increased the cell efficiency by decreasing the anode potential, but this was offset by decreased CO2 yields. Nonetheless, cycling increased the efficiency relative to constant potential. The maximum yields at PtRu and 80 °C were 13% at constant potential and 32% under potential cycling. The increased yields under cycling conditions have been attributed to periodic oxidative stripping of adsorbed CO, which occurs at lower potentials on PtRu than on Pt. These results will be important in the optimization of operating conditions for direct ethanol fuel cells and for the electrolysis of ethanol to produce clean hydrogen.
Yong, Xiao-Yu; Gu, Dong-Yan; Wu, Yuan-Dong; Yan, Zhi-Ying; Zhou, Jun; Wu, Xia-Yuan; Wei, Ping; Jia, Hong-Hua; Zheng, Tao; Yong, Yang-Chun
2017-02-15
The intensive use of triphenyltin chloride (TPTC) has caused serious environmental pollution. In this study, an effective method for TPTC degradation was proposed based on the Bio-Electron-Fenton process in microbial fuel cells (MFCs). The maximum voltage of the MFC with graphite felt as electrode was 278.47% higher than that of carbon cloth. The electricity generated by MFC can be used for in situ generation of H 2 O 2 to a maximum of 135.96μmolL -1 at the Fe@Fe 2 O 3(*) /graphite felt composite cathode, which further reacted with leached Fe 2+ to produce hydroxyl radicals. While 100μmolL -1 TPTC was added to the cathodic chamber, the degradation efficiency of TPTC reached 78.32±2.07%, with a rate of 0.775±0.021μmolL -1 h -1 . This Bio-Electron-Fenton driving TPTC degradation might involve in SnC bonds breaking and the main process is probably a stepwise dephenylation until the formation of inorganic tin and CO 2 . This study provides an energy saving and efficient approach for TPTC degradation. Copyright © 2016 Elsevier B.V. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Borole, Abhijeet P; Hamilton, Choo Yieng; Vishnivetskaya, Tatiana A
2011-01-01
Using a pre-enriched microbial consortium as the inoculum and continuous supply of carbon source, improvement in performance of a three-dimensional, flow-through MFC anode utilizing ferricyanide cathode was investigated. The power density increased from 170 W/m3 (1800 mW/m2) to 580 W/m3 (6130 mW/m2), when the carbon loading increased from 2.5 g/l-day to 50 g/l-day. The coulombic efficiency (CE) decreased from 90% to 23% with increasing carbon loading. The CEs are among the highest reported for glucose and lactate as the substrate with the maximum current density reaching 15.1 A/m2. This suggests establishment of a very high performance exoelectrogenic microbial consortium atmore » the anode. A maximum energy conversion efficiency of 54% was observed at a loading of 2.5 g/l-day. Biological characterization of the consortium showed presence of Burkholderiales and Rhodocyclales as the dominant members. Imaging of the biofilms revealed thinner biofilms compared to the inoculum MFC, but a 1.9-fold higher power density.« less
Maximum organic loading rate for the single-stage wet anaerobic digestion of food waste.
Nagao, Norio; Tajima, Nobuyuki; Kawai, Minako; Niwa, Chiaki; Kurosawa, Norio; Matsuyama, Tatsushi; Yusoff, Fatimah Md; Toda, Tatsuki
2012-08-01
Anaerobic digestion of food waste was conducted at high OLR from 3.7 to 12.9 kg-VS m(-3) day(-1) for 225 days. Periods without organic loading were arranged between the each loading period. Stable operation at an OLR of 9.2 kg-VS (15.0 kg-COD) m(-3) day(-1) was achieved with a high VS reduction (91.8%) and high methane yield (455 mL g-VS-1). The cell density increased in the periods without organic loading, and reached to 10.9×10(10) cells mL(-1) on day 187, which was around 15 times higher than that of the seed sludge. There was a significant correlation between OLR and saturated TSS in the sludge (y=17.3e(0.1679×), r(2)=0.996, P<0.05). A theoretical maximum OLR of 10.5 kg-VS (17.0 kg-COD) m(-3) day(-1) was obtained for mesophilic single-stage wet anaerobic digestion that is able to maintain a stable operation with high methane yield and VS reduction. Copyright © 2012 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Salas, Y.; Guerrero, L.; Blanco, J.; Jimenez, C.; Vera-Monroy, S. P.; Mejía-Camacho, A.
2017-12-01
In this work, DC electrochemical techniques were used to determine the corrosion rate of copper and stainless-steel electrodes used in grounding, varying the level of humidity, in sandy loam and clay loam soils. The maximum corrosion potentials were: for copper -211 and -236mV and for stainless steel of -252 and -281mV, in sandy loam and clay loam respectively, showing that in sandy loam the values are higher, about 30mV. The mechanism by which steel controls corrosion is by diffusion, whereas in copper it is carried out by transfer of mass and charge, which affects the rate of corrosion, which in copper reached a maximum value of 5mm/yr and in Steel 0.8mm/yr, determined by Tafel approximations. The behaviour of the corrosion rate was mathematically adjusted to an asymptotic model that faithfully explains the C.R. as a function of humidity, however, it is necessary to define the relation between the factor □ established in the model and the precise characteristics of the soil, such as the permeability or quantity of ions present.
Wang, Yunpu; Dai, Leilei; Fan, Liangliang; Cao, Leipeng; Zhou, Yue; Zhao, Yunfeng; Liu, Yuhuan; Ruan, Roger
2017-03-01
In this study, a ZrO 2 -based polycrystalline ceramic foam catalyst was prepared and used in catalytic co-pyrolysis of waste vegetable oil and high density polyethylene (HDPE) for hydrocarbon fuel production. The effects of pyrolysis temperature, catalyst dosage, and HDPE to waste vegetable oil ratio on the product distribution and hydrocarbon fuel composition were examined. Experimental results indicate that the maximum hydrocarbon fuel yield of 63.1wt. % was obtained at 430°C, and the oxygenates were rarely detected in the hydrocarbon fuel. The hydrocarbon fuel yield increased when the catalyst was used. At the catalyst dosage of 15wt.%, the proportion of alkanes in the hydrocarbon fuel reached 97.85wt.%, which greatly simplified the fuel composition and improved the fuel quality. With the augment of HDPE to waste vegetable oil ratio, the hydrocarbon fuel yield monotonously increased. At the HDPE to waste vegetable oil ratio of 1:1, the maximum proportion (97.85wt.%) of alkanes was obtained. Moreover, the properties of hydrocarbon fuel were superior to biodiesel and 0 # diesel due to higher calorific value, better low-temperature low fluidity, and lower density and viscosity. Copyright © 2017 Elsevier Ltd. All rights reserved.
Robards, Martin D.; Anthony, Jill A.; Rose, George A.; Piatt, John F.
1999-01-01
Mean dry-weight energy values of adult Pacific sand lance (Ammodytes hexapterus) peaked in spring and early summer (20.91 kJg−1 for males, 21.08 kJg−1 for females), then declined by about 25% during late summer and fall (15.91 kJg−1 for males, 15.74 kJg−1 for females). Late summer declines in energy density paralleled gonadal development. Gender differences in energy density (males
NASA Technical Reports Server (NTRS)
Pigeon, Pascale; Bortolami, Simone B.; DiZio, Paul; Lackner, James R.
2003-01-01
When reaching movements involve simultaneous trunk rotation, additional interaction torques are generated on the arm that are absent when the trunk is stable. To explore whether the CNS compensates for such self-generated interaction torques, we recorded hand trajectories in reaching tasks involving various amplitudes and velocities of arm extension and trunk rotation. Subjects pointed to three targets on a surface slightly above waist level. Two of the target locations were chosen so that a similar arm configuration relative to the trunk would be required for reaching to them, one of these targets requiring substantial trunk rotation, the other very little. Significant trunk rotation was necessary to reach the third target, but the arm's radial distance to the body remained virtually unchanged. Subjects reached at two speeds-a natural pace (slow) and rapidly (fast)-under normal lighting and in total darkness. Trunk angular velocity and finger velocity relative to the trunk were higher in the fast conditions but were not affected by the presence or absence of vision. Peak trunk velocity increased with increasing trunk rotation up to a maximum of 200 degrees /s. In slow movements, peak finger velocity relative to the trunk was smaller when trunk rotation was necessary to reach the targets. In fast movements, peak finger velocity was approximately 1.7 m/s for all targets. Finger trajectories were more curved when reaching movements involved substantial trunk rotation; however, the terminal errors and the maximal deviation of the trajectory from a straight line were comparable in slow and fast movements. This pattern indicates that the larger Coriolis, centripetal, and inertial interaction torques generated during rapid reaches were compensated by additional joint torques. Trajectory characteristics did not vary with the presence or absence of vision, indicating that visual feedback was unnecessary for anticipatory compensations. In all reaches involving trunk rotation, the finger movement generally occurred entirely during the trunk movement, indicating that the CNS did not minimize Coriolis forces incumbent on trunk rotation by sequencing the arm and trunk motions into a turn followed by a reach. A simplified model of the arm/trunk system revealed that additional interaction torques generated on the arm during voluntary turning and reaching were equivalent to < or =1.8 g (1 g = 9.81 m/s(2)) of external force at the elbow but did not degrade performance. In slow-rotation room studies involving reaching movements during passive rotation, Coriolis forces as small as 0.2 g greatly deflect movement trajectories and endpoints. We conclude that compensatory motor innervations are engaged in a predictive fashion to counteract impending self-generated interaction torques during voluntary reaching movements.
Pigeon, Pascale; Bortolami, Simone B; DiZio, Paul; Lackner, James R
2003-01-01
When reaching movements involve simultaneous trunk rotation, additional interaction torques are generated on the arm that are absent when the trunk is stable. To explore whether the CNS compensates for such self-generated interaction torques, we recorded hand trajectories in reaching tasks involving various amplitudes and velocities of arm extension and trunk rotation. Subjects pointed to three targets on a surface slightly above waist level. Two of the target locations were chosen so that a similar arm configuration relative to the trunk would be required for reaching to them, one of these targets requiring substantial trunk rotation, the other very little. Significant trunk rotation was necessary to reach the third target, but the arm's radial distance to the body remained virtually unchanged. Subjects reached at two speeds-a natural pace (slow) and rapidly (fast)-under normal lighting and in total darkness. Trunk angular velocity and finger velocity relative to the trunk were higher in the fast conditions but were not affected by the presence or absence of vision. Peak trunk velocity increased with increasing trunk rotation up to a maximum of 200 degrees /s. In slow movements, peak finger velocity relative to the trunk was smaller when trunk rotation was necessary to reach the targets. In fast movements, peak finger velocity was approximately 1.7 m/s for all targets. Finger trajectories were more curved when reaching movements involved substantial trunk rotation; however, the terminal errors and the maximal deviation of the trajectory from a straight line were comparable in slow and fast movements. This pattern indicates that the larger Coriolis, centripetal, and inertial interaction torques generated during rapid reaches were compensated by additional joint torques. Trajectory characteristics did not vary with the presence or absence of vision, indicating that visual feedback was unnecessary for anticipatory compensations. In all reaches involving trunk rotation, the finger movement generally occurred entirely during the trunk movement, indicating that the CNS did not minimize Coriolis forces incumbent on trunk rotation by sequencing the arm and trunk motions into a turn followed by a reach. A simplified model of the arm/trunk system revealed that additional interaction torques generated on the arm during voluntary turning and reaching were equivalent to < or =1.8 g (1 g = 9.81 m/s(2)) of external force at the elbow but did not degrade performance. In slow-rotation room studies involving reaching movements during passive rotation, Coriolis forces as small as 0.2 g greatly deflect movement trajectories and endpoints. We conclude that compensatory motor innervations are engaged in a predictive fashion to counteract impending self-generated interaction torques during voluntary reaching movements.
NASA Astrophysics Data System (ADS)
Poulos, Serafim; George, Ghionis; Karditsa, Aikaterini
2017-04-01
The present investigation concerns the application of the Article 8-2 of the Mediterranean ICZM protocol in the environmentally sensitive coastal dune field of the central part of the Kyparissiakos Gulf (Ionian Sea, Greece). The Kyparissiakos dune field, comprising a set of coastal ecosystems of exceptional value, needs effective ICZM and, amongst all, has to consider the issue of Sea-Level Rise (SLR). The dune field consists of "parabolic" type dunes that are stable and subjected locally to human interference. It consists of four shore-parallel dune lines: the outer (and most recently formed) 1st dune line has formed during the last 500 years, the 2nd during the last 1000 years, whilst the 3rd and 4th lines have formed not later than 1600 years BP (Poulos et al., 2012). Moreover, the four dune lines (from the youngest to the oldest) lie at distances of approximately 60 m, 100 m, 200 m and 600 m from the coastline, having maximum heights of 4 m, 6 m, 10 m, and 10-12 m, respectively. The dune field, in general, is in equilibrium with the current nearshore hydrodynamics as the width of the beach zone is greater than the maximum run-up length (not included storm surge). The maximum wave run-up height (R), relative to the mean sea level, has been calculated by applying Komar's (1998) equation: R = 0.36 ṡ g0.5 ṡ S ṡ Ho0.5 ṡ T (g: acceleration of gravity; Ho: maximum offshore wave height; T: corresponding maximum wave period; S: tangential beach slope). Thus, the wave run-up due to the highest incoming waves can reach elevations of the order of 1.6m in the case of the NW waves (Ho=6m, T=9 s) and 2m in the case of W and SW waves (Ho=6.4m, T=6.4s). These elevations correspond to 25m and 40 m of tangential distances on the beach surface, which are less than the current beach width (> 60 m). However, if the maximum wave heights coincide with the maximum storm surge (0.5 m) observed in the area, wave action can reach and erode the foot of the 1st dune line. Thus, for the current sea level, the maximum wave excursion would reach the line along the foot of the 1st dune line. The application of the Barcelona 2008 protocol requires a free zone of 100 m, landwards of the maximum wave elevation, in this case reaching the 2nd dune line. If the moderate scenario of sea level rise ca. 0.4 m (IPCC, 2013) is realised, extensive erosion is expected to take place, leading to the destruction of the 1st dune line and the formation of a new shoreline close to the foot of the 2nd dune line, which might be partially destroyed and reshaped by the transgressive landward transfer of dune material. On the basis of the above, for this particular sensitive coastal environment, even the 100 m set-back line might be inadequate, even for the moderate sea level rise scenario for the year 2100.
Quist, M.C.; Spiegel, J.R.
2011-01-01
Catostomids are among the most widespread and ecologically important groups of fishes in North America, particularly in large river systems. Despite their importance, little information is available on their population demographics and even less is known about factors influencing their population dynamics. The objectives of this study were to describe annual mortality, recruitment variation, and growth of eight catostomid species, and to evaluate the effects of discharge and temperature on year-class strength and growth in Iowa rivers. Catostomids were sampled from 3-km reaches in four nonwadable rivers during June–August 2009. Northern hogsucker, Hypentelium nigricans, golden redhorse, Moxostoma erythrurum, and shorthead redhorse, M. macrolepidotum, typically lived 6–8 years, had very stable recruitment, and had high total annual mortality (i.e., 40–60%). Golden redhorse exhibited the fastest growth of all species. Growth of northern hogsucker and shorthead redhorse was intermediate to the other catostomids. Highfin carpsucker, Carpiodes velifer, quillback, Carpiodes cyprinus, and white sucker, Catostomus commersonii, had high growth rates, low mortality (i.e., 25–30%), and relatively stable recruitment. River carpsucker, Carpiodes carpio, and silver redhorse, M. anisurum, had higher maximum ages (up to age 11), slower growth, lower total annual mortality (20–25%), and higher recruitment variability than the other species. Neither discharge nor temperature was strongly related to recruitment of catostomids. In contrast, several interesting patterns were observed with regard to growth. Species (e.g., carpsuckers, Carpiodes spp.) that typically consume prey items most common in fine substrates (e.g., chironomids) had higher growth rates in reaches dominated by sand and silt substrate. Species (e.g., northern hogsucker) that consume prey associated with large substrates (e.g., plecopterans) had much faster growth in reaches with a high proportion of rocky substrates. Temperature was weakly related to growth of catostomids; however, discharge explained a substantial amount of the variation in growth of nearly all species. Results of this study provide important information on the autecology of catostomids that can be used for comparison among species and systems. These data also suggest that connection of rivers with their floodplain is an important feature for catostomids in temperate river systems.
Ma, Rui; Huang, Xiaofei; Zhou, Yang; Fang, Lin; Sun, Shichang; Zhang, Peixin; Zhang, Xianghua; Zhao, Xuxin
2017-08-01
Adding catalyst could improve the yields and qualities of bio-gas and bio-oil, and realize the oriented production. Results showed that the catalytic gas-production capacities of CaO were higher than those of Fe 2 O 3 , and the bio-gas yield at 800°C reached a maximum of 35.1%. Because the polar cracking active sites of CaO reduced the activation energy of the pyrolysis reaction and resulted in high catalytic cracking efficiencies. In addition, the quality of bio-oil produced by CaO was superior to that by Fe 2 O 3 , although the bio-oil yield of CaO was relatively weak. The light bio-fuel oriented catalytic pyrolysis could be realized when adding different catalysts. At 800°C, CaO was 45% higher than Fe 2 O 3 in aspect of H 2 production while Fe 2 O 3 was 103% higher than CaO in aspect of CH 4 production. Therefore, CaO was more suitable for H 2 production and Fe 2 O 3 was more suitable for CH 4 production. Copyright © 2017 Elsevier Ltd. All rights reserved.
Xu, Juan; Luo, Hui; López, Claudia; Xiao, Jing; Chang, Yanhong
2015-10-01
The main goal of the present work is to investigate a novel process of purification and immobilization of a thermophilic catalase at high temperatures. The catalase, originated from Bacillus sp., was overexpressed in a recombinant Escherichia coli BL21(DE3)/pET28-CATHis and efficiently purified by heat treatment, achieving a threefold purification. The purified catalase was then immobilized onto an epoxy support at different temperatures (25, 40, and 55 °C). The immobilizate obtained at higher temperatures reached its maximum activity in a shorter time than that obtained at lower temperatures. Furthermore, immobilization at higher temperatures required a lower ionic strength than immobilization at lower temperatures. The characteristics of immobilized enzymes prepared at different temperatures were investigated. The high-temperature immobilizate (55 °C) showed the highest thermal stability, followed by the 40 °C immobilizate. And the high-temperature immobilizate (55 °C) had slightly higher operational stability than the 25 °C immobilizate. All of the immobilized catalase preparations showed higher stability than the free enzyme at alkaline pH 10.0, while the alkali resistance of the 25 °C immobilizate was slightly better than that of the 40 and 55 °C immobilizates.
Reaching Higher Gamma in Ultracold Neutral Plasmas Through Disorder-Induced Heating Control
2016-06-27
shielding ,” Phys. Rev. E 87, 033101 (2013) 4 Sequential ionization of ultracold plasma ions A simulation published in 2007 by Michael Murillo showed...AFRL-AFOSR-VA-TR-2017-0031 Reaching higher Gamma in ultracold neutral plasmas through disorder-induced heating control Scott Bergeson BRIGHAM YOUNG...TYPE Final Report 3. DATES COVERED (From - To) 01 June 2012 - 31 May 2016 4. TITLE AND SUBTITLE Reaching higher Gamma in ultracold neutral plasmas
14 CFR 25.331 - Symmetric maneuvering conditions.
Code of Federal Regulations, 2011 CFR
2011-01-01
... Conditions § 25.331 Symmetric maneuvering conditions. (a) Procedure. For the analysis of the maneuvering... factor (at point A2 in § 25.333(b)), or the resulting tailplane normal load reaches its maximum...
Photothermal characterization of the gelation process in Gelidium robustum Agar
NASA Astrophysics Data System (ADS)
Freile-Pelegrín, Y.; Bante, J.; Alvarado-Gil, J. J.; Yánez-Limón, J. M.
2005-06-01
Agar is a hydrophilic colloid formed by polysaccharides, whose ability to form reversible gels simply by cooling hot aqueous solutions is the most important property and can be regarded as the prototype and model for all gelling systems. In this paper the evolution of the gelation process of agar obtained from algae of the species Gelidium robustum, using the photopyroelectric technique is reported. It is shown that thermal effusivity increase when the agar is cooled, reaching a maximum value around 37°C. The increase in thermal effusivity can be related to the increasing of the bondings in the gel as temperature decreases, reaching the maximum at the gelation point. The decrease of the thermal effusivity at lower temperature could be due to the syneresis process involving a gradual release of water after gelation.
The synthesis of polyadenylated messenger RNA in herpes simplex type I virus infected BHK cells.
Harris, T J; Wildy, P
1975-09-01
The pattern of polyadenylated messenger RNA (mRNA) synthesis in BHK cell monolayers, infected under defined conditions with herpes simplex type I virus has been investigated by polyacrylamide gel electrophoresis or pulse-labelled RNA isolated by oligo dT-cellulose chromatography. Two classes of mRNA molecules were synthesized in infected cells; these were not detected in uninfected cells. The rate of synthesis of the larger, 18 to 30S RNA class reached a maximum soon after injection and then declined, whereas the rate of synthesis of the 7 to 11 S RNA class did not reach a maximum until much later and did not decline. In the presence of cytosine arabinoside, the rate of mRNA synthesis in infected cells was reduced but the electrophoretic pattern remained the same.
NASA Astrophysics Data System (ADS)
Vericat, Damia; Batalla, Ramon J.; Garcia, Celso
2006-06-01
Changes in armour layer during floods under supply limited conditions are little known. This paper describes the breakup and the reestablishment of the bed armour layer in the regulated gravel-bed Ebro River during a flooding period. The study was conducted over a 28-km study reach from 2002 to 2004. The surface, subsurface and bed load grain size distribution constitute the bases for the analysis of bed-armouring dynamics. The results indicate that the magnitude of floods controlled the degree of armouring of the river bed. The initial mean armouring ratio was 2.3, with maximum values reaching 4.4. Floods in the winter of 2002-2003 ( Q8) caused the breakup of the armour layer in several sections. This resulted in the erratic bed load pattern observed during the December 2002 flushing flow and in the increase in bed load transport during successive events. Most grain size classes were entrained and transported, causing river bed incision. The mean armouring ratio decreased to 1.9. In contrast, during low magnitude floods in 2003-2004 ( Q2), the coarsest fractions (64 mm) did not take part in the bed load while finer particles were winnowed, thus surface deposits coarsened. As a result, the armour layer was reestablished (i.e., the mean armouring ratio increased to 2.3), and the supply of subsurface sediment decreased. The supply and transport of bed material appear to be in balance in the river reach immediately below the dam. In contrast, the transport of medium and finer size classes in the downstream reaches was higher than their supply from upstream, a phenomenon that progressively reduced their availability in the river bed surface, hence the armour layer reworking.
The implications of basalt in the formation and evolution of mountains on Venus
NASA Astrophysics Data System (ADS)
Jull, Matthew G.; Arkani-Hamed, Jafar
1995-06-01
The highland region of Ishtar Terra on Venus has mountains that reach up to 11 km in height and are thought to be basaltic in composition. Assuming that dynamic uplift of crust to this height is unlikely, we examine the topography produced by an isostatically supported thickening basaltic crust. It is found that regardless of whether the crust thickens by crustal shortening or by volcanic construction, the high-density basalt-eclogite phase transition is the limiting factor for producing significant elevation of the mountains. The maximum height attained by basaltic mountains depends on the nature of the basalt-eclogite phase transition. Without a phase transition, a basaltic crust must thicken to greater than 100 km to reach heights over 10 km. An instantaneous phase transition of basalt to eclogite allows a maximum topographic height of less than about 2 km. However, with a time lag of 100 Ma owing to slow rates of solid-state diffusion, our calculations show that the mountains can reach elevations greater than 10 km only if they are less than 25 Ma old. Higher temperatures within the Venusian crust may decrease the extent of the stability fields of high-density basalt phases and allow high topography if the thickening crust melts. This can occur if the radioactive element concentrations measured on the surface of Venus are uniformly distributed throughout the crust, the crust thickens to greater than 65 km, and the thickened crust is older than about 400 Ma. The conflicting results of a young age predicted for high basaltic mountains and an almost uniform surface age of 500 Ma from crater populations, coupled with similarities in bulk physical properties of Venus and Earth, suggest that the basaltic surface composition found at several landing sites on the planet may not be representative of the entire crust. We suggest that Ishtar Terra formed from the collision of continent-like highly silicic cratons over a region of mantle downwelling. Lakshmi Planum resulted from the thickening of a basaltic crust and the peripheral mountain belts formed from the collision of granitic cratons that were pulled toward a downwelling region of mantle.
NASA Astrophysics Data System (ADS)
Böcker, Johannes; Littke, Ralf
2016-03-01
In the central Upper Rhine Graben (URG), several major oil fields have been sourced by Liassic Black Shales. In particular, the Posidonia Shale (Lias ɛ, Lower Toarcian) acts as excellent and most prominent source rock in the central URG. This study is the first comprehensive synthesis of Liassic maturity data in the URG area and SW Germany. The thermal maturity of the Liassic Black Shales has been analysed by vitrinite reflectance (VRr) measurements, which have been verified with T max and spore coloration index (SCI) data. In outcrops and shallow wells (<600 m), the Liassic Black Shales reached maturities equivalent to the very early or early oil window (ca. 0.50-0.60 % VRr). This maturity is found in Liassic outcrops and shallow wells in the entire URG area and surrounding Swabian Jura Mountains. Maximum temperatures of the Posidonia Shale before graben formation are in the order of 80-90 °C. These values were likely reached during Late Cretaceous times due to significant Upper Jurassic and minor Cretaceous deposition and influenced by higher heat flows of the beginning rift event at about 70 Ma. In this regard, the consistent regional maturity data (VRr, T max, SCI) of 0.5-0.6 % VRr for the Posidonia Shale close to surface suggest a major burial-controlled maturation before graben formation. These consistent maturity data for Liassic outcrops and shallow wells imply no significant oil generation and expulsion from the Posidonia Shale before formation of the URG. A detailed VRr map has been created using VRr values of 31 wells and outcrops with a structure map of the Posidonia Shale as reference map for a depth-dependent gridding operation. Highest maturity levels occur in the area of the Rastatt Trough (ca. 1.5 % VRr) and along the graben axis with partly very high VRr gradients (e.g. well Scheibenhardt 2). In these deep graben areas, the maximum temperatures which were reached during upper Oligocene to Miocene times greatly exceed those during the Cretaceous.
Getachew, Yehenew; Gotu, Butte; Enquselassie, Fikre
2010-10-01
Since early 1980s when AIDS was first recognized, there has been uncertainty about the future trend and the ultimate dimensions of the pandemic. This uncertainty persists because of difficulties in measuring HIV incidence and prevalence with a substantial degree of precision in a given population. One of the many factors for the lack of precision is the problem of obtaining representative data sources that can be extrapolated to the general population. National and regional HIV estimates for Ethiopia are derived from ANC based HIV surveillance data. Alternative data sources have not been exhaustively explored as potential tools to monitor the trend of HIV/ AIDS epidemic in the country. To estimate the magnitude and trend of HIV/AIDS epidemic using data from the routine VCT services as an alternative data source to ANC sentinel surveillance data. The study used secondary data sources from all government, private and NGO VCT centers, of the period of 2003-2005 in Addis Ababa. For the purpose of making comparative analysis of the VCT based estimations and projections, records of all five sentinel sites in Addis Ababa for the period 1983-2003 were reviewed. Both ANC and VCT data sources showed similar and regular trends from the beginning of the HIV epidemic till the year 1995 where the ANC showed a relatively higher prevalence rates than VCT data, with a maximum difference in HIV prevalence of 1.06% in 1993. However, a higher HIV prevalence was noted for the VCT than the ANC data source for the period of 1996-2002, with a maximum difference of 1.4% in 1998, the year when both the ANC and VCT modeled HIV prevalence reached the highest peak in Addis Ababa. On the contrary, the ANC based prevalence was higher than the VCT data for the period 2004-2010, with a maximum difference of 2.2%. This study suggests that VCT based HIV prevalence data closely approximates the ANC based data. Therefore VCT data source can be valuable to complement the ANC data in monitoring the HIV epidemic and trend.
Lobon-Cervia, J.; Gonzalez, G.; Budy, P.
2011-01-01
1.The objective was to identify the factors driving spatial and temporal variation in annual production (PA) and turnover (production/biomass) ratio (P/BA) of resident brown trout Salmo trutta in tributaries of the Rio Esva (Cantabrian Mountains, Asturias, north-western Spain). We examined annual production (total production of all age-classes over a year) (PA) and turnover (P/BA) ratios, in relation to year-class production (production over the entire life time of a year-class) (PT) and turnover (P/BT) ratio, over 14years at a total of 12 sites along the length of four contrasting tributaries. In addition, we explored whether the importance of recruitment and site depth for spatial and temporal variations in year-class production (PT), elucidated in previous studies, extends to annual production. 2.Large spatial (among sites) and temporal (among years) variation in annual production (range 1.9-40.3gm-2 per year) and P/BA ratio (range 0.76-2.4per year) typified these populations, values reported here including all the variation reported globally for salmonids streams inhabited by one or several species. 3.Despite substantial differences among streams and sites in all production attributes, when all data were pooled, annual (PA) and year-class production (PT) and annual (P/BA) and year-class P/BT ratios were tightly linked. Annual (PA) and year-class production (PT) were similar but not identical, i.e. PT=0.94 PA, whereas the P/BT ratios were 4+P/BA ratios. 4.Recruitment (Rc) and mean annual density (NA) were major density-dependent drivers of production and their relationships were described by simple mathematical models. While year-class production (PT) was determined (R2=70.1%) by recruitment (Rc), annual production (PA) was determined (R2=60.3%) by mean annual density (NA). In turn, variation in recruitment explained R2=55.2% of variation in year-class P/BT ratios, the latter attaining an asymptote at P/BT=6 at progressively higher levels of recruitment. Similarly, variations in mean annual density (NA) explained R2=52.1% of variation in annual P/BA, the latter reaching an asymptote at P/BA=2.1. This explained why P/BT is equal to P/BA plus the number of year-classes at high but not at low densities. 5.Site depth was a major determinant of spatial (among sites) variation in production attributes. All these attributes described two-phase trajectories with site depth, reaching a maximum at sites of intermediate depth and declining at shallower and deeper sites. As a consequence, at sites where recruitment and mean annual density reached minimum or maximum values, annual (PA) and year-class production (PT) and annual (P/BA) and year-class P/BT ratios also reached minimum and maximum values. ?? 2011 Blackwell Publishing Ltd.
SubspaceEM: A Fast Maximum-a-posteriori Algorithm for Cryo-EM Single Particle Reconstruction
Dvornek, Nicha C.; Sigworth, Fred J.; Tagare, Hemant D.
2015-01-01
Single particle reconstruction methods based on the maximum-likelihood principle and the expectation-maximization (E–M) algorithm are popular because of their ability to produce high resolution structures. However, these algorithms are computationally very expensive, requiring a network of computational servers. To overcome this computational bottleneck, we propose a new mathematical framework for accelerating maximum-likelihood reconstructions. The speedup is by orders of magnitude and the proposed algorithm produces similar quality reconstructions compared to the standard maximum-likelihood formulation. Our approach uses subspace approximations of the cryo-electron microscopy (cryo-EM) data and projection images, greatly reducing the number of image transformations and comparisons that are computed. Experiments using simulated and actual cryo-EM data show that speedup in overall execution time compared to traditional maximum-likelihood reconstruction reaches factors of over 300. PMID:25839831
DOE Office of Scientific and Technical Information (OSTI.GOV)
Winter, L. M.; Balasubramaniam, K. S., E-mail: lwinter@aer.com
We present an alternate method of determining the progression of the solar cycle through an analysis of the solar X-ray background. Our results are based on the NOAA Geostationary Operational Environmental Satellites (GOES) X-ray data in the 1-8 Å band from 1986 to the present, covering solar cycles 22, 23, and 24. The X-ray background level tracks the progression of the solar cycle through its maximum and minimum. Using the X-ray data, we can therefore make estimates of the solar cycle progression and the date of solar maximum. Based upon our analysis, we conclude that the Sun reached its hemisphere-averagedmore » maximum in solar cycle 24 in late 2013. This is within six months of the NOAA prediction of a maximum in spring 2013.« less
Ayalasomayajula, Surya; Langenickel, Thomas; Pal, Parasar; Boggarapu, Sreedevi; Sunkara, Gangadhar
2017-12-01
Sacubitril/valsartan (LCZ696) is indicated for the treatment of heart failure with reduced ejection fraction. Absorption of sacubitril/valsartan and conversion of sacubitril (prodrug) to sacubitrilat (neprilysin inhibitor) was rapid with maximum plasma concentrations of sacubitril, sacubitrilat, and valsartan (angiotensin receptor blocker) reaching within 0.5, 1.5-2.0, and 2.0-3.0 h, respectively. With a two-fold increase in dose, an increase in the area under the plasma concentration-time curve was proportional for sacubitril, ~1.9-fold for sacubitrilat, and ~1.7-fold for valsartan in healthy subjects. Following multiple twice-daily administration, steady-state maximum plasma concentration was reached within 3 days, showing no accumulation for sacubitril and valsartan, while ~1.6-fold accumulation for sacubitrilat. Sacubitril is eliminated predominantly as sacubitrilat through the kidney; valsartan is eliminated mainly by biliary route. Drug-drug interactions of sacubitril/valsartan were evaluated with medications commonly used in patients with heart failure including furosemide, warfarin, digoxin, carvedilol, levonorgestrel/ethinyl estradiol combination, amlodipine, omeprazole, hydrochlorothiazide, intravenous nitrates, metformin, statins, and sildenafil. Co-administration with sacubitril/valsartan increased the maximum plasma concentration (~2.0-fold) and area under the plasma concentration-time curve (1.3-fold) of atorvastatin; however, it did not affect the pharmacokinetics of simvastatin. Age, sex, or ethnicity did not affect the pharmacokinetics of sacubitril/valsartan. In patients with heart failure vs. healthy subjects, area under the plasma concentration-time curves of sacubitril, sacubitrilat, and valsartan were higher by approximately 1.6-, 2.1-, and 2.3-fold, respectively. Renal impairment had no significant impact on sacubitril and valsartan area under the plasma concentration-time curves, while the area under the plasma concentration-time curve of sacubitrilat correlated with degree of renal function (1.3-, 2.3-, 2.9-, and 3.3-fold with mild, moderate, and severe renal impairment, and end-stage renal disease, respectively). Moderate hepatic impairment increased the area under the plasma concentration-time curves of valsartan and sacubitrilat ~2.1-fold.
Ayalasomayajula, Surya; Langenickel, Thomas; Pal, Parasar; Boggarapu, Sreedevi; Sunkara, Gangadhar
2018-01-01
Sacubitril/valsartan (LCZ696) is indicated for the treatment of heart failure with reduced ejection fraction. Absorption of sacubitril/valsartan and conversion of sacubitril (prodrug) to sacubitrilat (neprilysin inhibitor) was rapid with maximum plasma concentrations of sacubitril, sacubitrilat, and valsartan (angiotensin receptor blocker) reaching within 0.5, 1.5-2.0, and 2.0-3.0 h, respectively. With a twofold increase in dose, an increase in the area under the plasma concentration-time curve was proportional for sacubitril, ~1.9-fold for sacubitrilat, and ~1.7-fold for valsartan in healthy subjects. Following multiple twice-daily administration, steady-state maximum plasma concentration was reached within 3 days, showing no accumulation for sacubitril and valsartan, while ~1.6-fold accumulation for sacubitrilat. Sacubitril is eliminated predominantly as sacubitrilat through the kidney; valsartan is eliminated mainly by biliary route. Drug-drug interactions of sacubitril/valsartan were evaluated with medications commonly used in patients with heart failure including furosemide, warfarin, digoxin, carvedilol, levonorgestrel/ethinyl estradiol combination, amlodipine, omeprazole, hydrochlorothiazide, intravenous nitrates, metformin, statins, and sildenafil. Co-administration with sacubitril/valsartan increased the maximum plasma concentration (~2.0-fold) and area under the plasma concentration-time curve (1.3-fold) of atorvastatin; however, it did not affect the pharmacokinetics of simvastatin. Age, sex, or ethnicity did not affect the pharmacokinetics of sacubitril/valsartan. In patients with heart failure vs. healthy subjects, area under the plasma concentration-time curves of sacubitril, sacubitrilat, and valsartan were higher by approximately 1.6-, 2.1-, and 2.3-fold, respectively. Renal impairment had no significant impact on sacubitril and valsartan area under the plasma concentration-time curves, while the area under the plasma concentration-time curve of sacubitrilat correlated with degree of renal function (1.3-, 2.3-, 2.9-, and 3.3-fold with mild, moderate, and severe renal impairment, and end-stage renal disease, respectively). Moderate hepatic impairment increased the area under the plasma concentration-time curves of valsartan and sacubitrilat ~2.1-fold.
NASA Astrophysics Data System (ADS)
Hu, S. X.; Gao, R.; Ding, Y.; Collins, L. A.; Kress, J. D.
2017-04-01
Using density-functional theory-based molecular-dynamics simulations, we have investigated the equation of state for silicon in a wide range of plasma density and temperature conditions of ρ =0.001 -500 g /c m3 and T =2000 -108K . With these calculations, we have established a first-principles equation-of-state (FPEOS) table of silicon for high-energy-density (HED) plasma simulations. When compared with the widely used SESAME-EOS model (Table 3810), we find that the FPEOS-predicted Hugoniot is ˜20% softer; for off-Hugoniot plasma conditions, the pressure and internal energy in FPEOS are lower than those of SESAME EOS for temperatures above T ≈ 1-10 eV (depending on density), while the former becomes higher in the low-T regime. The pressure difference between FPEOS and SESAME 3810 can reach to ˜50%, especially in the warm-dense-matter regime. Implementing the FPEOS table of silicon into our hydrocodes, we have studied its effects on Si-target implosions. When compared with the one-dimensional radiation-hydrodynamics simulation using the SESAME 3810 EOS model, the FPEOS simulation showed that (1) the shock speed in silicon is ˜10% slower; (2) the peak density of an in-flight Si shell during implosion is ˜20% higher than the SESAME 3810 simulation; (3) the maximum density reached in the FPEOS simulation is ˜40% higher at the peak compression; and (4) the final areal density and neutron yield are, respectively, ˜30% and ˜70% higher predicted by FPEOS versus the traditional simulation using SESAME 3810. All of these features can be attributed to the larger compressibility of silicon predicted by FPEOS. These results indicate that an accurate EOS table, like the FPEOS presented here, could be essential for the precise design of targets for HED experiments.
Deterministic approach for multiple-source tsunami hazard assessment for Sines, Portugal
NASA Astrophysics Data System (ADS)
Wronna, M.; Omira, R.; Baptista, M. A.
2015-11-01
In this paper, we present a deterministic approach to tsunami hazard assessment for the city and harbour of Sines, Portugal, one of the test sites of project ASTARTE (Assessment, STrategy And Risk Reduction for Tsunamis in Europe). Sines has one of the most important deep-water ports, which has oil-bearing, petrochemical, liquid-bulk, coal, and container terminals. The port and its industrial infrastructures face the ocean southwest towards the main seismogenic sources. This work considers two different seismic zones: the Southwest Iberian Margin and the Gloria Fault. Within these two regions, we selected a total of six scenarios to assess the tsunami impact at the test site. The tsunami simulations are computed using NSWING, a Non-linear Shallow Water model wIth Nested Grids. In this study, the static effect of tides is analysed for three different tidal stages: MLLW (mean lower low water), MSL (mean sea level), and MHHW (mean higher high water). For each scenario, the tsunami hazard is described by maximum values of wave height, flow depth, drawback, maximum inundation area and run-up. Synthetic waveforms are computed at virtual tide gauges at specific locations outside and inside the harbour. The final results describe the impact at the Sines test site considering the single scenarios at mean sea level, the aggregate scenario, and the influence of the tide on the aggregate scenario. The results confirm the composite source of Horseshoe and Marques de Pombal faults as the worst-case scenario, with wave heights of over 10 m, which reach the coast approximately 22 min after the rupture. It dominates the aggregate scenario by about 60 % of the impact area at the test site, considering maximum wave height and maximum flow depth. The HSMPF scenario inundates a total area of 3.5 km2.
Howell, P.J.; Dunham, J.B.; Sankovich, P.M.
2010-01-01
Understanding thermal habitat use by migratory fish has been limited by difficulties in matching fish locations with water temperatures. To describe spatial and temporal patterns of thermal habitat use by migratory adult bull trout, Salvelinus confluentus, that spawn in the Lostine River, Oregon, we employed a combination of archival temperature tags, radio tags, and thermographs. We also compared temperatures of the tagged fish to ambient water temperatures to determine if the fish were using thermal refuges. The timing and temperatures at which fish moved upstream from overwintering areas to spawning locations varied considerably among individuals. The annual maximum 7-day average daily maximum (7DADM) temperatures of tagged fish were 16-18 ??C and potentially as high as 21 ??C. Maximum 7DADM ambient water temperatures within the range of tagged fish during summer were 18-25 ??C. However, there was no evidence of the tagged fish using localized cold water refuges. Tagged fish appeared to spawn at 7DADM temperatures of 7-14 ??C. Maximum 7DADM temperatures of tagged fish and ambient temperatures at the onset of the spawning period in late August were 11-18 ??C. Water temperatures in most of the upper Lostine River used for spawning and rearing appear to be largely natural since there has been little development, whereas downstream reaches used by migratory bull trout are heavily diverted for irrigation. Although the population effects of these temperatures are unknown, summer temperatures and the higher temperatures observed for spawning fish appear to be at or above the upper range of suitability reported for the species. Published 2009. This article is a US Governmentwork and is in the public domain in the USA.
A pantropical analysis of the impacts of forest degradation and conversion on local temperature.
Senior, Rebecca A; Hill, Jane K; González Del Pliego, Pamela; Goode, Laurel K; Edwards, David P
2017-10-01
Temperature is a core component of a species' fundamental niche. At the fine scale over which most organisms experience climate (mm to ha), temperature depends upon the amount of radiation reaching the Earth's surface, which is principally governed by vegetation. Tropical regions have undergone widespread and extreme changes to vegetation, particularly through the degradation and conversion of rainforests. As most terrestrial biodiversity is in the tropics, and many of these species possess narrow thermal limits, it is important to identify local thermal impacts of rainforest degradation and conversion. We collected pantropical, site-level (<1 ha) temperature data from the literature to quantify impacts of land-use change on local temperatures, and to examine whether this relationship differed aboveground relative to belowground and between wet and dry seasons. We found that local temperature in our sample sites was higher than primary forest in all human-impacted land-use types (N = 113,894 daytime temperature measurements from 25 studies). Warming was pronounced following conversion of forest to agricultural land (minimum +1.6°C, maximum +13.6°C), but minimal and nonsignificant when compared to forest degradation (e.g., by selective logging; minimum +1°C, maximum +1.1°C). The effect was buffered belowground (minimum buffering 0°C, maximum buffering 11.4°C), whereas seasonality had minimal impact (maximum buffering 1.9°C). We conclude that forest-dependent species that persist following conversion of rainforest have experienced substantial local warming. Deforestation pushes these species closer to their thermal limits, making it more likely that compounding effects of future perturbations, such as severe droughts and global warming, will exceed species' tolerances. By contrast, degraded forests and belowground habitats may provide important refugia for thermally restricted species in landscapes dominated by agricultural land.
Nutrient Removal through Oyster Habitat Restoration in the Indian River Lagoon, Florida
NASA Astrophysics Data System (ADS)
Gallagher, S. M.; Schmidt, C. A.; Walters, L.; Blank, R.
2017-12-01
In 2016, an algae bloom in the Indian River Lagoon (IRL) caused a state of emergency in Florida. As with many estuaries, nutrient loading in the IRL has led to periodic eutrophication. While previous studies have shown oyster bed restoration reduces suspended organic matter in estuaries, similar reductions to net nutrient loads are not well established. In addition, previous studies have focused on seasonal variation rather than ongoing yearly effects. Here, we determine the net nitrogen and phosphorus effects of oyster restoration in the IRL over seven years. Analysis of aerial images from 1943 and 2009 showed 14.7 ha of oyster beds were destroyed by boat traffic in the IRL (40% loss). According to our measurements of restored oyster bed sediment, this equates to a maximum of 1,580,000 kg•N•yr-1 of lost denitrification potential; this is equivalent to 150% of estimated current nitrogen loading in the IRL. Oyster restoration began in the IRL in 2007 and has recovered 7.7% of the lost beds and denitrification potential (1.13 ha and 107,000 kg•N•yr-1•ha-1). In all cases, denitrification reached a maximum within two years and remained significantly higher than open sediment for at least the seven years observed. Denitrification benefits came at the cost of mobilizing a maximum of 3450 kg ha-1 of recalcitrant phosphorus from restored bed sediment. This effect was limited to the two years following restoration, whereas increased denitrification was ongoing. Overall, our results show oyster restoration achieved maximum denitrification within two years and maintained significant denitrification benefits for at least seven years. In addition, our results are useful for future oyster restoration projects since they quantify nitrogen benefits in terms of phosphorus mobilization.
18 CFR 12.38 - Time for inspections and reports.
Code of Federal Regulations, 2011 CFR
2011-04-01
... reaches its normal maximum surface elevation, whichever occurs first. (3) For any development not set... information and analyses required by § 12.37(b). (c) Extension of time. For good cause shown, the Regional...
Simulation Analysis of Wireless Power Transmission System for Biomedical Applications
NASA Astrophysics Data System (ADS)
Yang, Zhao; Wei, Zhiqiang; Chi, Haokun; Yin, Bo; Cong, Yanping
2018-03-01
In recent years, more and more implantable medical devices have been used in the medical field. Some of these devices, such as brain pacemakers, require long-term power support. The WPT(wireless power transmission) technology which is more convenient and economical than replacing the battery by surgery, has become the first choice of many patients. In this paper, we design a WPT system that can be used in implantable medical devices, simulate the transmission efficiency of the system in the air and in the head model, and simulate the SAR value when the system working in the head model. The results show that when implantation depth of the secondary coil is 3 mm, the efficiency of the system can reach 45%, and the maximum average SAR value is 2.19 W / kg, slightly higher than the standard of IEEE.
Pattern optimization of compound optical film for uniformity improvement in liquid-crystal displays
NASA Astrophysics Data System (ADS)
Huang, Bing-Le; Lin, Jin-tang; Ye, Yun; Xu, Sheng; Chen, En-guo; Guo, Tai-Liang
2017-12-01
The density dynamic adjustment algorithm (DDAA) is designed to efficiently promote the uniformity of the integrated backlight module (IBLM) by adjusting the microstructures' distribution on the compound optical film (COF), in which the COF is constructed in the SolidWorks and simulated in the TracePro. In order to demonstrate the universality of the proposed algorithm, the initial distribution is allocated by the Bezier curve instead of an empirical value. Simulation results maintains that the uniformity of the IBLM reaches over 90% only after four rounds. Moreover, the vertical and horizontal full width at half maximum of angular intensity are collimated to 24 deg and 14 deg, respectively. Compared with the current industry requirement, the IBLM has an 85% higher luminance uniformity of the emerging light, which demonstrate the feasibility and universality of the proposed algorithm.
Dordio, Ana V; Duarte, Cátia; Barreiros, Margarida; Carvalho, A J Palace; Pinto, A P; da Costa, Cristina Teixeira
2009-02-01
A study was conducted to assess Typha spp.'s ability to withstand and remove, from water, a metabolite of blood lipid regulator drugs, clofibric acid (CA). At a concentration of 20 microg L(-1), Typha had removed >50% of CA within the first 48h, reaching a maximum of 80% by the end of the assay. Experimental conditions assured that photodegradation, adsorption to vessel walls and microbial degradation did not contribute to the removal. Exposure to higher CA concentrations did not affect Typha's photosynthetic pigments but the overall increase in enzyme activity (ascorbate and guaiacol peroxidases, catalase, superoxide dismutase) indicates that both roots and leaves were affected by the xenobiotic. Eventually, Typha seemed able to cope with the CA's induced oxidative damage suggesting its ability for phytoremediation of CA contaminated waters.
Mahajan, Richi V; Saran, Saurabh; Kameswaran, Karthikeya; Kumar, Vinod; Saxena, R K
2012-12-01
L-Asparaginase has potential as an anti-cancer drug and for prevention of acrylamide formation in fried and baked foods. Production of the enzyme by Bacillus licheniformis (RAM-8) was optimized by process engineering using a statistical modeling approach and a maximum yield of 32.26 IU/ml was achieved. The L-asparaginase exhibited glutaminase activity of only 0.8 IU/ml and would therefore be less prone to cause the side effects associated with asparaginase therapy compared to enzyme preparations with higher glutaminase activities. When production was carried out in a 30-L bioreactor, enzyme production reached 29.94 IU/ml in 15 h. The enzyme inhibited poly-acrylamide formation in 10% acrylamide solution and reduced acrylamide formation in fried potatoes by 80%. Copyright © 2012 Elsevier Ltd. All rights reserved.
Magnetic properties and large reversible magnetocaloric effect in Er3Pd2
NASA Astrophysics Data System (ADS)
Maji, Bibekananda; Ray, Mayukh K.; Modak, M.; Mondal, S.; Suresh, K. G.; Banerjee, S.
2018-06-01
The magnetic properties and magnetocaloric effect (MCE) of binary intermetallic compound Er3Pd2 were studied. It exhibits a paramagnetic (PM) to antiferromagnetic (AFM) transition at Néel temperature (TN) = 10 K. A large reversible MCE was observed which is related to a second order magnetic transition from PM to AFM state. The values of maximum magnetic entropy change (- Δ SMmax) and adiabatic temperature change (Δ Tadmax) reach 8.9 J/kg-K and 2.9 K respectively for the field change of 50 kOe with no obvious hysteresis loss. The effective magnetic moment was determined to be 10.16 μB/Er3+, which is notably higher than that of free ion value of Er3+ (9.59 μB), suggests that Pd ions also have considerable amount of magnetic moments in this compound.
Effect of pulsed electric fields upon accumulation of zinc in Saccharomyces cerevisiae.
Pankiewicz, Urszula; Jamroz, Jerzy
2011-06-01
Cultures of Saccharomyces cerevisiae were treated with pulsed electric fields to improve accumulation of zinc in the biomass. Under optimized conditions, that is, on 15 min exposure of the 20 h grown culture to PEFs of 1500 V and 10 microns pulse width, accumulation of zinc in the yeast biomass reached a maximum of 15.57 mg/g d.m. Under optimum zinc concentration (100 microgram/ml nutrient medium), its accumulation in the cells was higher by 63% in comparison with the control (without PEFs). That accumulation significantly correlated against zinc concentration in the medium. Neither multiple exposure of the cultures to PEFs nor intermittent supplementation of the cultures with zinc increased the zinc accumulation. The intermittent supplementation of the cultures with zinc and multiple exposures on PEFs could even reduce the accumulation efficiency, respectively, by 57% and 47%.
NASA Technical Reports Server (NTRS)
2004-01-01
KENNEDY SPACE CENTER, FLA. In the Orbiter Processing Facility, a technician appears to ride the Space Shuttle Main Engine (SSME) as he maneuvers the SSME on the Hyster lift into position for installation on Discovery, the vehicle designated for the Return to Flight mission STS-114. Overall, an SSME weighs approximately 7,000 pounds. An SSME operates at greater temperature extremes than any mechanical system in common use today. The liquid hydrogen fuel is -423 degrees Fahrenheit, the second coldest liquid on Earth. When the hydrogen is burned with liquid oxygen, the temperature in the engine's combustion chamber reaches +6000 degrees Fahrenheit -- that's higher than the boiling point of Iron. The maximum equivalent horsepower developed by the three SSMEs is just over 37 million horsepower. The energy released by the three SSMEs is equivalent to the output of 23 Hoover Dams.
NASA Technical Reports Server (NTRS)
2004-01-01
KENNEDY SPACE CENTER, FLA. In the Orbiter Processing Facility, a technician appears to ride the Space Shuttle Main Engine (SSME) as he maneuvers the SSME on the Hyster lift into position for installation on Discovery, the vehicle designated for the Return to Flight mission STS-114. Overall, an SSME weighs approximately 7,000 pounds. An SSME operates at greater temperature extremes than any mechanical system in common use today. The liquid hydrogen fuel is -423 degrees Fahrenheit, the second coldest liquid on Earth. When the hydrogen is burned with liquid oxygen, the temperature in the engine's combustion chamber reaches +6000 degrees Fahrenheit -- that's higher than the boiling point of Iron. The maximum equivalent horsepower developed by the three SSMEs is just over 37 million horsepower. The energy released by the three SSMEs is equivalent to the output of 23 Hoover Dams.
NASA Astrophysics Data System (ADS)
Hahm, D.; Hilton, D. R.; Cho, M.; Wei, H.; Kim, K.-R.
2008-11-01
We report new He and CO2 data for geothermal fluids from Changbaishan Volcano located on the border of China and North Korea. Helium isotope ratios reach a maximum of 5.4 RA (where RA = 3He/4He in air) whereas carbon isotope values (δ 13C) fall between -2 and -7 ‰ (vs. PDB). The ratio of CO2/3He varies between 0.5-7.1 (×109) for gas samples but is considerably higher (~1012) in waters. The combined He-CO2 systematics reveal the clear imprint of a dominant subducted slab contribution to the total CO2 inventory. We conclude that these geothermal volatiles originate from the sub-continental lithospheric mantle (SCLM) in NE China and represent ancient fluids captured by prior metasomatic events.
Absorption and Scattering of Aerosol measured onboard R/V Gisang1 over the Yellow Sea
NASA Astrophysics Data System (ADS)
Inae, K.; Lee, M.; Shin, B.; Ryoo, S.; Jung, J.; Kim, S. W.
2017-12-01
Absorption and scattering coefficient were measured onboard RV Gisang 1 over the Yellow Sea (covering 124° 127°E, 31° 38°N) during May June, 2016. BC concentration was analyzed at seven wavelengths (370, 470, 520, 590, 660, 880, and 950nm) every 1 minute by Aethalometer. Scattering coefficient was measured at three wavelengths (450, 550, and 750nm) every 5 minutes with Nephelometer. The mean absorption coefficient was 1.2 Mm-1 at 880nm and the mean scattering coefficient was 116Mm-1 at 550nm. Single scattering albedo(SSA) reached the maximum value of 3.0 at 700nm. The calculated mean scattering angstrom exponent(SAE) was 1.6 and absorbing angstrom exponent(AAE) was 1.1. The AAE and SAE were higher in aged Chinese plume.
What limits the morphological disparity of clades?
Oyston, Jack W.; Hughes, Martin; Wagner, Peter J.; Gerber, Sylvain; Wills, Matthew A.
2015-01-01
The morphological disparity of species within major clades shows a variety of trajectory patterns through evolutionary time. However, there is a significant tendency for groups to reach their maximum disparity relatively early in their histories, even while their species richness or diversity is comparatively low. This pattern of early high-disparity suggests that there are internal constraints (e.g. developmental pleiotropy) or external restrictions (e.g. ecological competition) upon the variety of morphologies that can subsequently evolve. It has also been demonstrated that the rate of evolution of new character states decreases in most clades through time (character saturation), as does the rate of origination of novel bodyplans and higher taxa. Here, we tested whether there was a simple relationship between the level or rate of character state exhaustion and the shape of a clade's disparity profile: specifically, its centre of gravity (CG). In a sample of 93 extinct major clades, most showed some degree of exhaustion, but all continued to evolve new states up until their extinction. Projection of states/steps curves suggested that clades realized an average of 60% of their inferred maximum numbers of states. Despite a weak but significant correlation between overall levels of homoplasy and the CG of clade disparity profiles, there were no significant relationships between any of our indices of exhaustion curve shape and the clade disparity CG. Clades showing early high-disparity were no more likely to have early character saturation than those with maximum disparity late in their evolution. PMID:26640649
Borgquist, Ola; Ingemansson, Richard; Malmsjö, Malin
2011-02-01
Negative-pressure wound therapy promotes healing by drainage of excessive fluid and debris and by mechanical deformation of the wound. The most commonly used negative pressure, -125 mmHg, may cause pain and ischemia, and the pressure often needs to be reduced. The aim of the present study was to examine wound contraction and fluid removal at different levels of negative pressure. Peripheral wounds were created in 70-kg pigs. The immediate effects of negative-pressure wound therapy (-10 to -175 mmHg) on wound contraction and fluid removal were studied in eight pigs. The long-term effects on wound contraction were studied in eight additional pigs during 72 hours of negative-pressure wound therapy at -75 mmHg. Wound contraction and fluid removal increased gradually with increasing levels of negative pressure until reaching a steady state. Maximum wound contraction was observed at -75 mmHg. When negative-pressure wound therapy was discontinued, after 72 hours of therapy, the wound surface area was smaller than before therapy. Maximum wound fluid removal was observed at -125 mmHg. Negative-pressure wound therapy facilitates drainage of wound fluid and exudates and results in mechanical deformation of the wound edge tissue, which is known to stimulate granulation tissue formation. Maximum wound contraction is achieved already at -75 mmHg, and this may be a suitable pressure for most wounds. In wounds with large volumes of exudate, higher pressure levels may be needed for the initial treatment period.
Wang, Y X; Ngo, H H; Guo, W S
2015-11-15
The studied bamboo based activated carbon (BbAC) with high specific surface area (SSA) and high micro pore volume was prepared from bamboo scraps by the combined activation of H3PO4 and K2CO3. The BbAC was characterized based on the N2 adsorption isotherm at 77K. The results showed that the SSA and pore volume of BbAC increased with increasing impregnation ratio and reached maxima at the impregnation ratio of 3:1 at 750°C. Under these optimal conditions, the BbAC obtained could have a maximum SSA of 2237 m(2)/g and a maximum total pore volume of 1.23 cm(3)/g with the micro pore ratio of more than 90%. The adsorption performance of ciprofloxacin (CIP) on the BbAC was determined at 298 K. The Langmuir and Freundlich models were employed to describe the adsorption equilibrium and the kinetic data were fitted by pseudo first-order and pseudo second-order kinetic models. The results showed that the Langmuir model and the pseudo second-order kinetic model presented better fittings for the adsorption equilibrium and kinetics data, respectively. The maximum adsorption amount of CIP (613 mg/g) on the BbAC was much higher than the report in the literature. Conclusively, the BbAC could be a promising adsorption material for CIP removal from water. Copyright © 2015 Elsevier B.V. All rights reserved.
Paul Sclafani
2011-01-01
The Middle Rio Grande is a 29-mi reach of the Rio Grande River in central New Mexico that extends from downstream of Cochiti Dam to Bernalillo, New Mexico. A series of anthropogenic factors including the construction of flood control levees and Cochiti Dam have altered the historically-braided morphology of the Middle Rio Grande to a more sinuous, degrading reach, with...
GPS Enabled Semi-Autonomous Robot
2017-09-01
equal and the goal has not yet been reached (i.e., any time the robot has reached a local minimum), and direct the robot to travel in a specific...whether the robot was turning or not. The challenge is overcome by ensuring the robot travels at its maximum speed at all times . Further research into...robot’s fixed reference frame was recalculated each time through the control loop. If the encoder data allows for the robot to appear to have travelled
Verdoni, N; Aon, M A; Lebeault, J M; Thomas, D
1990-01-01
Batch cultures of Pseudomonas mendocina, grown in rich medium with glucose excess, showed metabolic differences dependent upon whether the growth conditions were aerobic or anaerobic, with or without added electron acceptor. Under anaerobic conditions in the absence of nitrate, P. mendocina reached the stationary phase of growth after 2 or 3 days, followed by a stationary phase of 4 to 5 days. Under these conditions, a mixed-type fermentative metabolism (formic, lactic, and acetic acids) appeared. A fivefold-higher specific rate of glucose consumption and eightfold-higher production of organic acids, compared with aerobic cultures, were shown by this microorganism growing anaerobically in the absence of exogenous electron acceptors. The gradients of organic acid produced by P. mendocina under these conditions reached a maximum (lactate, 180 mV; formate, 150 mV; acetate, 215 mV) between days 2 and 3 of culture. The proton motive force (delta p) decreased during growth from -254 to -71 mV. The intracellular pH remained alkaline during the culture, reaching a steady-state value of 7.9. The gradients of organic acids apparently contributed to the generation of a delta p, which, according to the Energy Recycling Model (P. A. M. Michels, J. P. J. Michels, J. Boonstra, and W. N. Konings, FEMS Microbiol. Lett. 5:357-364, 1979), would produce an average energy gain of 1 or 1.5 mol of ATP equivalents per mol of glucose consumed with H+/ATP stoichiometry of 3 or 2, respectively. Low YATP and Yglucose values were observed, suggesting that an uncoupled metabolism exists; i.e., ATP produced by catabolic processes is not directly used for biomass synthesis. This metabolic uncoupling could be induced at least in part by organic acids and the ATP wastage could be induced by a membrane-bound ATPase involved in intracellular pH regulation. PMID:2254245
Wilberg, Dale E.; Stolp, Bernard J.
2005-01-01
This report contains the results of an October 2001 seepage investigation conducted along a reach of the Escalante River in Utah extending from the U.S. Geological Survey streamflow-gaging station near Escalante to the mouth of Stevens Canyon. Discharge was measured at 16 individual sites along 15 consecutive reaches. Total reach length was about 86 miles. A reconnaissance-level sampling of water for tritium and chlorofluorcarbons was also done. In addition, hydrologic and water-quality data previously collected and published by the U.S. Geological Survey for the 2,020-square-mile Escalante River drainage basin was compiled and is presented in 12 tables. These data were collected from 64 surface-water sites and 28 springs from 1909 to 2002.None of the 15 consecutive reaches along the Escalante River had a measured loss or gain that exceeded the measurement error. All discharge measurements taken during the seepage investigation were assigned a qualitative rating of accuracy that ranged from 5 percent to greater than 8 percent of the actual flow. Summing the potential error for each measurement and dividing by the maximum of either the upstream discharge and any tributary inflow, or the downstream discharge, determined the normalized error for a reach. This was compared to the computed loss or gain that also was normalized to the maximum discharge. A loss or gain for a specified reach is considered significant when the loss or gain (normalized percentage difference) is greater than the measurement error (normalized percentage error). The percentage difference and percentage error were normalized to allow comparison between reaches with different amounts of discharge.The plate that accompanies the report is 36" by 40" and can be printed in 16 tiles, 8.5 by 11 inches. An index for the tiles is located on the lower left-hand side of the plate. Using Adobe Acrobat, the plate can be viewed independent of the report; all Acrobat functions are available.
An inverse dynamic analysis on the influence of upper limb gravity compensation during reaching.
Essers, J M N Hans; Meijer, Kenneth; Murgia, Alessio; Bergsma, Arjen; Verstegen, Paul
2013-06-01
Muscular dystrophies (MDs) are characterized by progressive muscle wasting and weakness. Several studies have been conducted to investigate the influence of arm supports in an attempt to restore arm function. Lowering the load allows the user to employ the residual muscle force for movement as well as for posture stabilization. In this pilot study three conditions were investigated during a reaching task performed by three healthy subjects and three MD subjects: a control condition involving reaching; a similar movement with gravity compensation using braces to support the forearm; an identical reaching movement in simulated zero-gravity. In the control condition the highest values of shoulder moments were present, with a maximum of about 6 Nm for shoulder flexion and abduction. In the gravity compensation and zero gravity conditions the maximum shoulder moments were decreased by more than 70% and instead of increasing during reaching, they remained almost unvaried, fluctuating around an offset value less than 1 Nm. Similarly, the elbow moments in the control condition were the highest with a peak around 3.3 Nm for elbow flexion, while the moments were substantially reduced in the remaining two conditions, fluctuating around offset values between 0 to 0.5 Nm. In conclusion, gravity compensation by lower arm support is effective in healthy subjects and MD subjects and lowers the amount of shoulder and elbow moments by an amount comparable to a zero gravity environment. However the influence of gravity compensation still needs to be investigated on more people with MDs in order to quantify any beneficial effect on this population.
Estimation of reach in peripersonal and extrapersonal space: a developmental view.
Gabbard, Carl; Cordova, Alberto; Ammar, Diala
2007-01-01
This study explored the developmental nature of action processing via estimation of reach in peripersonal and extrapersonal space. Children 5 to 11 years of age and adults were tested for estimates of reach to targets presented randomly at seven midline locations. Target distances were scaled to the individual based on absolute maximum reach. While there was no difference between age groups for total error, a significant distinction emerged in reference to space. With children, significantly more error was exhibited in extrapersonal space; no difference was found with adults. The groups did not differ in peripersonal space; however, adults were substantially more accurate with extrapersonal targets. Furthermore, children displayed a greater tendency to overestimate. In essence, these data reveal a body-scaling problem in children in estimating reach in extrapersonal space. Future work should focus on possible developmental differences in use of visual information and state of confidence.
Emissions of indoor air pollutants from six user scenarios in a model room
NASA Astrophysics Data System (ADS)
Höllbacher, Eva; Ters, Thomas; Rieder-Gradinger, Cornelia; Srebotnik, Ewald
2017-02-01
In this study six common user scenarios putatively influencing indoor air quality were performed in a model room constructed according to the specifications of the European Reference Room given in the new horizontal prestandard prEN 16516 to gain further information about the influence of user activities on indoor air quality. These scenarios included the use of cleaning agent, an electric air freshener, an ethanol fireplace and cosmetics as well as cigarette smoking and peeling of oranges. Four common indoor air pollutants were monitored: volatile organic compounds (VOC), particulate matter (PM), carbonyl compounds and CO2. The development of all pollutants was determined during and after the test performance. For each measured pollutant, well-defined maximum values could be assigned to one or more of the individual user scenarios. The highest VOC concentration was measured during orange-peeling reaching a maximum value of 3547 μg m-3. Carbonyl compounds and PM were strongly elevated while cigarette smoking. Here, a maximum formaldehyde concentration of 76 μg m-3 and PM concentration of 378 μg m-3 were measured. CO2 was only slightly affected by most of the tests except the use of the ethanol fireplace where a maximum concentration of 1612 ppm was reached. Generally, the user scenarios resulted in a distinct increase of several indoor pollutants that usually decreased rapidly after the removal of the source.
NASA Astrophysics Data System (ADS)
Ortega-Casanova, Joaquin; Fernandez-Feria, Ramon
2015-11-01
The thrust generated by two heaving plates in tandem is analysed for two particular sets of configurations of interest in forward flight: a plunging leading plate with the trailing plate at rest, and the two plates heaving with the same frequency and amplitude, but varying the phase difference. The thrust efficiency of the leading plate is augmented in relation to a single plate heaving with the same frequency and amplitude in most cases. In the first configuration, we characterize the range of nondimensional heaving frequencies and amplitudes of the leading plate for which the stationary trailing plate contributes positively to the global thrust. The maximum global thrust efficiency, reached for an advance ratio slightly less than unity and a reduced frequency close to 5, is about the same as the maximum efficiency for an isolated plate. But for low frequencies the tandem configuration with the trailing plate at rest is more thrust efficient than the isolated plate. In the second configuration, we find that the maximum thrust efficiency is reached for a phase lag of 180o (counterstroking), particularly for an advance ratio unity and a reduced frequency 4.4, and it is practically the same as in the other configuration and that for a single plate. Supported by the Ministerio de Economía y Competitividad of Spain Grant no. DPI2013-40479-P.
NASA Technical Reports Server (NTRS)
West, F E
1945-01-01
Lift characteristics and pressure distribution for a NACA 230 wing were investigated for an angle of attack range of from -10 to +24 degrees and Mach range of from 0.2 to 0.7. Maximum lift coefficient increased up to a Mach number of 0.3, decreased rapidly to a Mach number of 0.55, and then decreased moderately. At high speeds, maximum lift coefficient was reached at from 10 to 12 degrees beyond the stalling angle. In high-speed stalls, resultant load underwent a moderate shift outward.
X-ray observations of the burst source MXB 1728 - 34
NASA Technical Reports Server (NTRS)
Basinska, E. M.; Lewin, W. H. G.; Sztajno, M.; Cominsky, L. R.; Marshall, F. J.
1984-01-01
Where sufficient information has been obtained, attention is given to the maximum burst flux, integrated burst flux, spectral hardness, rise time, etc., of 96 X-ray bursts observed from March 1976 to March 1979. The integrated burst flux and the burst frequency appear to be correlated; the longer the burst interval, the larger the integrated burst flux, as expected on the basis of simple thermonuclear flash models. The maximum burst flux and the integrated burst flux are strongly correlated; for low flux levels their dependence is approximately linear, while for increasing values of the integrated burst flux, the flux at burst maximum saturates and reaches a plateau.
The ESS neutrino facility for CP violation discovery
NASA Astrophysics Data System (ADS)
Baussan, Eric; Bouquerel, Elian; Dracos, Marcos
2017-09-01
The comparatively large value of the neutrino mixing angle θ 13 measured in 2012 by neutrino reactor experiments has opened the possibility to observe for the first time CP violation in the leptonic sector. The measured value of θ 13 also privileges the 2nd oscillation maximum for the discovery of CP violation instead of the usually used 1st oscillation maximum. The sensitivity at the 2nd oscillation maximum is about three times higher than at the 1st oscillation maximum implying a significantly lower sensitivity to systematic errors. Measuring at the 2nd oscillation maximum necessitates a very intense neutrino beam with the appropriate energy. The world’s most intense pulsed spallation neutron source, the European Spallation Source, has a proton linac with 5 MW power and 2 GeV energy. This linac also has the potential to become the proton driver of the world’s most intense neutrino beam with very high potential for the discovery of neutrino CP violation. The physics performance of that neutrino Super Beam in conjunction with a megaton Water Cherenkov neutrino detector installed ca 1000 m down in a mine at a distance of about 500 km from ESS has been evaluated. In addition, the use of such a detector will make it possible to extent the physics program to proton decay, atmospheric neutrinos and astrophysics searches. The ESS proton linac upgrade, the accumulator ring needed for proton pulse compression, the target station optimization and the physics potential are described. In addition to the production of neutrinos, this facility will also be a copious source of muons which could be used to feed a low energy nuSTORM facility, a future neutrino factory or a muon collider. The ESS linac, under construction, will reach full operation at 5 MW by 2023 after which the upgrades for the neutrino facility could start.
[Echolocation calls of free-flying Himalayan swiftlets (Aerodramus brevirostris)].
Wang, Bin; Ma, Jian-Zhang; Chen, Yi; Tan, Liang-Jing; Liu, Qi; Shen, Qi-Qi; Liao, Qing-Yi; Zhang, Li-Biao
2013-02-01
Here, we present our findings of free-flying echolocation calls of Himalayan swiftlets (Aerodramus brevirostris), which were recorded in Shenjing Cave, Hupingshan National Reserve, Shimen County, Hunan Province in June 2012, using Avisoft-UltraSoundGate 116(e). We noted that after foraging at dusk, the Himalayan swiftlets flew fast into the cave without clicks, and then slowed down in dark area in the cave, but with sounds. The echolocation sounds of Himalayan swiftlets are broadband, double noise burst clicks, separated by a short pause. The inter-pulse intervals between double clicks (99.3±3.86 ms)were longer than those within double clicks (6.6±0.42 ms) (P<0.01). With the exception of peak frequency, between 6.2±0.08 kHz and 6.2±0.10 kHz, (P>0.05) and pulse duration 2.9±0.12 ms, 3.2±0.17 ms, (P>0.05) between the first and second, other factors-maximum frequency, minimum frequency, frequency bandwidth, and power-were significantly different between the clicks. The maximum frequency of the first pulse (20.1±1.10 kHz) was higher than that of second (15.4±0.98 kHz) (P<0.01), while the minimum frequency of the first pulse (3.7±0.12 kHz) was lower than that of second (4.0±0.09 kHz) (P<0.05); resulting in the frequency bandwidth of the first pulse (16.5±1.17 kHz) longer than that of second (11.4±1.01 kHz) (P<0.01). The power of the first pulse (-32.5±0.60 dB) was higher than that of second (-35.2±0.94 dB) (P<0.05). More importantly, we found that Himalayan swiftlets emitted echolocation pulses including ultrasonic sound, with a maximum frequency reaching 33.2 kHz.
Levofloxacin Pharmacokinetics in Adult Cystic Fibrosis
Lee, Carlton K. K.; Boyle, Michael P.; Diener-West, Marie; Brass-Ernst, Lois; Noschese, Michelle; Zeitlin, Pamela L.
2007-01-01
Background Cystic fibrosis (CF) patients have enhanced renal clearance of aminoglycosides and several β-lactams and require higher dosages. Levofloxacin is a fluoroquinolone with extensive renal elimination and enhanced penetration into lungs and Pseudomonas aeruginosa (PA) biofilms. We studied the preliminary pharmacokinetic and pharmacodynamic (PK/PD) relationship of levofloxacin in CF. Methods Twelve patients at least 18 years old with a mild-to-moderate pulmonary exacerbation and fluoroquinolone-sensitive PA colonization received oral levofloxacin, 500 mg qd, for 14 days. Steady-state serum concentrations were collected after 3 to 7 days, and sputum samples for PA densities were collected before and after levofloxacin. PK/PD relationships for reducing PA sputum densities were evaluated. Results When compared to published data on non-CF patients, CF patients had similar area under the curve for 24 h (AUC24), total clearance, volume of distribution, maximum serum concentration (Cpmax), and elimination half-life: mean, 7.33 μg × h/mL/kg (SD, 1.70); 2.43 mL/min/kg (SD, 0.74); 1.33 L/kg (SD, 0.37); 7.06 μg/mL (SD, 2.35); and 6.44 h (SD, 1.1), respectively. Time to reach maximum serum concentration (Tmax) in CF was longer: mean, 2.20 h (SD, 0.99) vs 1.1 h (SD, 0.4) [p < 0.01]. Preliminary PK/PD analysis failed to demonstrate trends for decreasing PA sputum densities with increasing Cpmax/minimum inhibitory concentration (MIC) ratio and AUC24/MIC ratio. Conclusion CF levofloxacin pharmacokinetics corrected for body weight are similar to non-CF, except for Tmax. Standard levofloxacin dosing (especially monotherapy) is unlikely to produce maximum therapeutic effectiveness. Additional levofloxacin studies in CF are necessary to evaluate its sputum concentrations; the benefits of higher daily dosages (≥ 750 mg); and establish PK/PD targets for managing PA pulmonary infections. PMID:17356095
Feucht, Matthias J; Grande, Eduardo; Brunhuber, Johannes; Rosenstiel, Nikolaus; Burgkart, Rainer; Imhoff, Andreas B; Braun, Sepp
2014-01-01
Posterior medial meniscus root (PMMR) tears have a serious effect on knee joint biomechanics. Currently used techniques for refixation of the PMMR include the transtibial pull-out repair (TP) and suture anchor repair (SA). These techniques have not been compared biomechanically. The SA technique provides superior biomechanical properties compared with the TP technique. Controlled laboratory study. A total of 24 fresh-frozen porcine tibiae with attached intact medial menisci were used. The specimens were randomly assigned to 3 groups (8 specimens each). A standardized PMMR tear was created in 16 specimens. Refixation of the PMMR was performed by either the TP or SA technique. The native PMMR was left intact in 8 specimens. All specimens were subjected to cyclic loading followed by load-to-failure testing. Displacement after 100, 500, and 1000 cycles; maximum load to failure; stiffness; and displacement at failure were recorded. Both repair techniques showed a significantly higher displacement during cyclic loading and a significantly lower maximum load and stiffness during load-to-failure testing compared with the native PMMR (P < .05). The SA technique showed a significantly lower displacement after 100, 500, and 1000 cycles (P < .001) and a significantly higher stiffness (P = .016) compared with the TP technique. Maximum load did not differ significantly between the SA and TP techniques (P = .027, Bonferroni adjustment). No significant difference between the 3 groups was observed for displacement at failure (P > .05). The SA technique provided superior biomechanical properties compared with the TP technique. Both repair techniques did not reach the strength of the native PMMR. The favorable biomechanical properties of the SA technique might be beneficial for healing of the repaired PMMR and restoration of meniscus function. Because of inferior time zero stability compared with the native PMMR, slow rehabilitation is recommended after meniscus root repair.
Tao, Yu-Qiang; Lei, Guo-Liang; Xue, Bin; Yao, Shu-Chun; Pu, Yang; Zhang, Hu-Cai
2014-02-01
Tibetan Plateau is the world's highest plateau, which provides a unique location for the investigation of global fractionation of organochlorine pesticides (OCPs). In this study, deposition and regional distribution of HCHs and p,p'-DDX in the western and southern Tibetan Plateau were investigated by the records from a sediment core of Lake Zige Tangco and 24 surface soils. Concentration of ΣHCHs in the surface soils of the western Tibetan Plateau was much higher than that of the southern part. Maximum fluxes of α-, β-, and δ-HCH in the sediment core were 9.0, 222, and 21 pg cm(-2) year(-1), respectively, which appeared in the mid-1960s. Significant correlations were observed between concentrations of α- and β-HCH in both the surface soils and the sediment core. Concentrations of both α- and β-HCH increased with the inverse of the average annual temperature of these sites. γ-HCH became the dominant isomer of HCHs after the late 1970s, and reached the maximum flux of 160 pg cm(-2) year(-1) in the early 1990s. There were no significant correlations between concentrations of γ-HCH and the other isomers in both the surface soils and the sediment core. The results suggested that there was input of Lindane at scattered sites in this area. In contrast to ΣHCHs, concentration of Σp,p'-DDX in the surface soils of the southern part was much higher than that of the western part. Maximum flux of Σp,p'-DDX was 44 pg cm(-2) year(-1), which appeared in the mid-1960s. Local emission of p,p'-DDT was found at scattered sites. This study provides novel data and knowledge for the OCPs in the western and southern Tibetan Plateau, which will help understand the global fractionation of OCPs in remote alpine regions.
Distribution of leaf characteristics in relation to orientation within the canopy of woody species
NASA Astrophysics Data System (ADS)
Escudero, Alfonso; Fernández, José; Cordero, Angel; Mediavilla, Sonia
2013-04-01
Over the last few decades considerable effort has been devoted to research of leaf adaptations to environmental conditions. Many studies have reported strong differences in leaf mass per unit area (LMA) within a single tree depending on the photosynthetic photon flux density (PPFD) incident on different locations in the crown. There are fewer studies, however, of the effects of differences in the timing of light incidence during the day on different crown orientations. Leaves from isolated trees of Quercus suber and Quercus ilex in a cold Mediterranean climate were sampled to analyze differences in LMA and other leaf traits among different crown orientations. Gas-exchange rates, leaf water potentials, leaf temperatures and PPFD incident on leaf surfaces in different crown orientations were also measured throughout one entire summer day for each species. Mean daily PPFD values were similar for the leaves from the eastern and western sides of the canopy. On the western side, PPFD reached maximum values during the afternoon. Maximum leaf temperatures were approximately 10-20% higher on the west side, whereas minimum leaf water potentials were between 10 and 24% higher on the east side. Maximum transpiration rates were approximately 22% greater on the west, because of the greater leaf-to-air vapor pressure deficits (LAVPD). Mean individual leaf area was around 10% larger on the east than on the west side of the trees. In contrast, there were no significant differences in LMA between east and west sides of the crown. Contrary to our expectations, more severe water stress on the west side did not result in increases in LMA, although it was associated with lower individual leaf area. We conclude that increases in LMA measured by other authors along gradients of water stress would be due to differences in light intensity between dry and humid sites.
Evidence of L-mode electromagnetic wave pumping of ionospheric plasma near geomagnetic zenith
NASA Astrophysics Data System (ADS)
Leyser, Thomas B.; James, H. Gordon; Gustavsson, Björn; Rietveld, Michael T.
2018-02-01
The response of ionospheric plasma to pumping by powerful HF (high frequency) electromagnetic waves transmitted from the ground into the ionosphere is the strongest in the direction of geomagnetic zenith. We present experimental results from transmitting a left-handed circularly polarized HF beam from the EISCAT (European Incoherent SCATter association) Heating facility in magnetic zenith. The CASSIOPE (CAScade, Smallsat and IOnospheric Polar Explorer) spacecraft in the topside ionosphere above the F-region density peak detected transionospheric pump radiation, although the pump frequency was below the maximum ionospheric plasma frequency. The pump wave is deduced to arrive at CASSIOPE through L-mode propagation and associated double (O to Z, Z to O) conversion in pump-induced radio windows. L-mode propagation allows the pump wave to reach higher plasma densities and higher ionospheric altitudes than O-mode propagation so that a pump wave in the L-mode can facilitate excitation of upper hybrid phenomena localized in density depletions in a larger altitude range. L-mode propagation is therefore suggested to be important in explaining the magnetic zenith effect.
Influence of resonator length on catastrophic optical damage in high-power AlGaInP broad-area lasers
NASA Astrophysics Data System (ADS)
Bou Sanayeh, Marwan
2017-05-01
The increasing importance of extracting high optical power out of semiconductor lasers motivated several studies in catastrophic optical damage (COD) level improvement. In this study, the influence of the resonator length in high-power broad-area (BA) AlGaInP lasers on COD is presented. For the analyses, several 638 nm AlGaInP 60 μm BA lasers from the same wafer were used. Resonator lengths of 900, 1200, 1500, and 1800 μm were compared. In order to independently examine the effect of the resonator length on the maximum power reached by the lasers before COD (PCOD), the lasers used are uncoated and unmounted, and PCOD under pulsed mode was determined. It was found that higher output powers and eventually higher PCOD can be achieved using longer resonators; however, it was also found that this is mainly useful when working at high output powers far away from the laser threshold, since the threshold current and slope efficiency worsen when the resonator length increases.
Zhao, Zhigang; Dong, Yantao; Pan, Sunqiang; Liu, Chong; Chen, Jun; Tong, Lixin; Gao, Qingsong; Tang, Chun
2012-01-16
A large aperture fused silica tapered fiber phase conjugate mirror is presented with a maximum 70% stimulated Brillouin scattering (SBS) reflectivity, which is obtained with 1 kHz repetition rate, 15 ns pulse width and 38 mJ input pulse energy. To the best of our knowledge, this is the highest SBS reflectivity ever reported by using optical fiber as a phase conjugate mirror for such high pulse repetition rate (1 kHz) and several tens of millijoule (mJ) input pulse energy. The influences of fiber end surface quality and pump pulse widths on SBS reflectivity are investigated experimentally. The results show that finer fiber end surface quality and longer input pulse widths are preferred for obtaining higher SBS reflectivity with higher input pulse energy. Double passing amplification experiments are also performed. 52 mJ pulse energy is achieved at 1 kHz repetition rate, with a reflected SBS pulse width of 1.5 ns and a M(2) factor of 2.3. The corresponding peak power reaches 34.6 MW. Obvious beam quality improvement is observed.
NASA Technical Reports Server (NTRS)
Hudson, C. M.; Lewis, P. E.
1979-01-01
A round-robin study was conducted which evaluated and compared different methods currently in practice for predicting crack growth in surface-cracked specimens. This report describes the prediction methods used by the Fracture Mechanics Engineering Section, at NASA-Langley Research Center, and presents a comparison between predicted crack growth and crack growth observed in laboratory experiments. For tests at higher stress levels, the correlation between predicted and experimentally determined crack growth was generally quite good. For tests at lower stress levels, the predicted number of cycles to reach a given crack length was consistently higher than the experimentally determined number of cycles. This consistent overestimation of the number of cycles could have resulted from a lack of definition of crack-growth data at low values of the stress intensity range. Generally, the predicted critical flaw sizes were smaller than the experimentally determined critical flaw sizes. This underestimation probably resulted from using plane-strain fracture toughness values to predict failure rather than the more appropriate values based on maximum load.
Effect of elicitors on the evolution of grape phenolic compounds during the ripening period.
Gómez-Plaza, Encarna; Bautista-Ortín, Ana B; Ruiz-García, Yolanda; Fernández-Fernández, José I; Gil-Muñoz, Rocío
2017-02-01
The effect of the application of benzothiadiazole (BTH) and methyl jasmonate (MeJ) at veraison on the phenolic composition of grapes from three varieties (Monastrell, Syrah and Merlot) was studied during the ripening period, using HPLC techniques to measure flavonols, anthocyanins and tannins. The effects of the treatments differed in the three varieties, and the maximum concentration of phenolic compounds was not always reached at the end of the ripening period but some days before harvest. At the end of ripening both treated Syrah grapes only differed from control grapes in the flavonol concentration, whereas MeJ-treated Merlot grapes presented higher anthocyanin and skin tannin contents than the control and BTH-treated grapes. Only the anthocyanin content was significantly higher in treated Monastrell grapes at the moment of harvest. The results indicate that the moment of elicitor treatment should be more studied since differences between treated and control grapes were, in general greater several days before harvest in all three varieties. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.
Normal and pathological serum levels of alpha2-macroglobulins in men and mice.
Tunstall, A M; Merriman, J M; Milne, I; James, K
1975-01-01
The serum levels of alpha2-macroglobulin have been measured in normal men and mice and in a number of immunopathological conditions. Normal human concentrations are high in youth, reach their minimum in middle age, and gradually increase with old age. In all age groups the mean is higher in the female than in the male. Conversely, in normal mice the alpha2M level is low in youth, maximum in middle age, and shows a slight depression with old age, and the levels are frequently higher in males than in females; there are also strain variations. In human immunopathological conditions, there are some deviations from the normal alpha2M level but these are seen to be changes from the normal distribution of values around the mean, rather than significant elevation or depression of mean values. In some disease states studied there are differences between the sexes in the deviation from normal. "Abnormal" strains of mice had alpha2M levels within the range exhibited by "normal" mice but changes in the levels are seen in mice with various myelomas. Images PMID:47865
Efficient Neutron Production from a Novel Configuration of Deuterium Gas-Puff Z-Pinch
NASA Astrophysics Data System (ADS)
Klir, D.; Kubes, P.; Rezac, K.; Cikhardt, J.; Kravarik, J.; Sila, O.; Shishlov, A. V.; Kovalchuk, B. M.; Ratakhin, N. A.; Kokshenev, V. A.; Labetsky, A. Yu.; Cherdizov, R. K.; Fursov, F. I.; Kurmaev, N. E.; Dudkin, G. N.; Nechaev, B. A.; Padalko, V. N.; Orcikova, H.; Turek, K.
2014-03-01
A novel configuration of a deuterium z pinch has been used to generate fusion neutrons. Injecting an outer hollow cylindrical plasma shell around an inner deuterium gas puff, neutron yields from DD reactions reached Yn=(2.9±0.3)×1012 at 700 ns implosion time and 2.7 MA current. Such a neutron yield means a tenfold increase in comparison with previous deuterium gas puff experiments at the same current generator. The increase of beam-target yields was obtained by a larger amount of current assembled on the z-pinch axis, and subsequently by higher induced voltage and higher energies of deuterons. A stack of CR-39 track detectors on the z-pinch axis showed hydrogen ions up to 38 MeV. Maximum neutron energies of 15 and 22 MeV were observed by radial and axial time-of-flight detectors, respectively. The number of DD neutrons per one joule of stored plasma energy approached 5×107. This implies that deuterium gas puff z pinches belong to the most efficient plasma-based sources of DD neutrons.
Study on hot melt pressure sensitive coil material for removing surface nuclear pollution dust
NASA Astrophysics Data System (ADS)
Wang, Jing; Li, Jiao; Wang, Jianhui; Zheng, Li; Li, Jian; Lv, Linmei
2018-02-01
A new method for removing surface nuclear pollution by using hot melt pressure sensitive membrane was presented. The hot melt pressure sensitive membrane was designed and prepared by screening hot melt pressure sensitive adhesive and substrate. The simulated decontamination test of the hot melt pressure sensitive membrane was performed by using 100 mesh and 20 mesh standard sieve dust for simulation of nuclear explosion fall ash and radioactive contaminated particles, respectively. It was found that the single decontamination rate of simulated fall ash and contaminated particles were both above 80% under pressure conditions of 25kPa or more at 140°C. And the maximum single decontamination rate was 92.5%. The influence of heating temperature and pressure on the decontamination rate of the membrane was investigated at the same time. The results showed that higher heating temperature could increase the decontamination rate by increasing the viscosity of the adhesive. When the adhesive amount of the adhesive layer reached saturation, a higher pressure could increase the single decontamination rate also.
Bitome Essono, Paul Yannick; Dechaume-Moncharmont, François-Xavier; Mavoungou, Jacques; Obiang Mba, Régis; Duvallet, Gérard; Bretagnolle, François
2015-01-01
In order to minimize risks of pathogen transmission with the development of ecotourism in Gabon, a seasonal inventory has been performed in five contrasted biotopes in Ivindo (INP) and Moukalaba-Doudou (MDNP) National Parks. A total of 10,033 hematophagous flies were captured. The Glossinidae, with six different species identified, was the most abundant group and constitutes about 60% of the captured flies compared to the Stomoxys (6 species also identified) and Tabanidae with 28% and 12%, respectively. The Glossinidae showed a higher rate of capture in primary forest and in research camps. In INP, the Stomoxys showed a higher rate of capture in secondary forest and at village borders, whereas in MDNP the Stomoxys were captured more in the savannah area. Thus, each fly group seemed to reach maximum abundance in different habitats. The Glossinidae were more abundant in primary forest and near research camps while Stomoxys were more abundant in secondary forest and savannah. The Tabanidae did not show a clear habitat preference. © P.Y. Bitome Essono et al., published by EDP Sciences, 2015.
Optimization of the biomass production of oil algae Chlorella minutissima UTEX2341.
Li, ZhaoSheng; Yuan, HongLi; Yang, JinShui; Li, BaoZhen
2011-10-01
High production cost is a major obstacle to the extensive use of microalgae biodiesel. To cut the cost and achieve higher biomass productivity, Chlorella minutissima UTEX2341 was cultured under photoheterotrophic conditions. With the carbon, nitrogen and phosphorus concentration of 26.37, 2.61 and 0.03 g L⁻¹ d⁻¹ respectively, a maximum biomass productivity of 1.78 g L⁻¹ d⁻¹ was obtained, which was 59 times more than that cultured under autotrophic condition. The lipid productivity reached 0.29 g L⁻¹ d⁻¹, which was 11.9 times higher than the highest value reported by Oh et al. (2010). The conversion rate of microalgae lipids to FAME was found to be elevated from 45.65% to 62.97% and the FAME productivity increased from 1.16 to 180.68 mg L⁻¹ d⁻¹ after the optimization. 94% of the fatty acid of C. minutissima UTEX2341 was found to be composed of palmitic, oleic, linoleic and γ linoleic and the unsaturated fatty acids were the main parts (79.42%). Copyright © 2011 Elsevier Ltd. All rights reserved.
Yong, Xiao-Yu; Yan, Zhi-Ying; Shen, Hai-Bo; Zhou, Jun; Wu, Xia-Yuan; Zhang, Li-Juan; Zheng, Tao; Jiang, Min; Wei, Ping; Jia, Hong-Hua; Yong, Yang-Chun
2017-10-01
Microbial fuel cell (MFC) is a promising device for energy generation and organic waste treatment simultaneously by electrochemically active bacteria (EAB). In this study, an integrated aerobic-anaerobic strategy was developed to improve the performance of P. aeruginosa-inoculated MFC. With an aerobic start-up and following an anaerobic discharge process, the current density of MFC reached a maximum of 99.80µA/cm 2 , which was 91.6% higher than the MFC with conventional constant-anaerobic operation. Cyclic voltammetry and HPLC analysis showed that aerobic start-up significantly increased electron shuttle (pyocyanin) production (76% higher than the constant-anaerobic MFC). Additionally, enhanced anode biofilm formation was also observed in the integrated aerobic-anaerobic MFC. The increased pyocyanin production and biofilm formation promoted extracellular electron transfer from EAB to the anode and were the underlying mechanism for the MFC performance enhancement. This work demonstrated the integrated aerobic-anaerobic strategy would be a practical strategy to enhance the electricity generation of MFC. Copyright © 2017 Elsevier Ltd. All rights reserved.
Acid Green 1 removal from wastewater by layered double hydroxides
NASA Astrophysics Data System (ADS)
Elkhattabi, El Hassan; Lakraimi, Mohamed; Berraho, Moha; Legrouri, Ahmed; Hammal, Radouan; El Gaini, Layla
2018-03-01
The paper presents the removal of Acid Green 1 (AG1) from aqueous solutions by [Zn-Al-Cl]-layered double hydroxides (LDHs). The LDH was prepared by coprecipitation at constant pH. The affinity of this material for AG1 was studied as a function of contact time, pH of the solution, LDH dose and AG1/LDH mass ratio. It was found that 32 h are enough to reach the equilibrium with a maximum retention at pH 8 for an LDH dose of 100 mg and with an AG1/LDH mass ratio higher than 2. The adsorption isotherm is of L-type, as described by the Langmuir model. The results demonstrate that AG1 retention on LDHs occurs by adsorption on external surface when AG1/LDH mass ratio is equal or lower than 2 and by both adsorption and interlayer ion exchange for ratios higher than 2. A mechanism for the AG1 removal has been confirmed by X-ray diffraction, Fourier transform infrared spectroscopy, thermogravimetric-differential thermal analyses and scanning electron microscopy.
Maslia, Morris L.; Aral, Mustafa M.; Ruckart, Perri Z.; Bove, Frank J.
2017-01-01
A U.S. government health agency conducted epidemiological studies to evaluate whether exposures to drinking water contaminated with volatile organic compounds (VOC) at U.S. Marine Corps Base Camp Lejeune, North Carolina, were associated with increased health risks to children and adults. These health studies required knowledge of contaminant concentrations in drinking water—at monthly intervals—delivered to family housing, barracks, and other facilities within the study area. Because concentration data were limited or unavailable during much of the period of contamination (1950s–1985), the historical reconstruction process was used to quantify estimates of monthly mean contaminant-specific concentrations. This paper integrates many efforts, reports, and papers into a synthesis of the overall approach to, and results from, a drinking-water historical reconstruction study. Results show that at the Tarawa Terrace water treatment plant (WTP) reconstructed (simulated) tetrachloroethylene (PCE) concentrations reached a maximum monthly average value of 183 micrograms per liter (μg/L) compared to a one-time maximum measured value of 215 μg/L and exceeded the U.S. Environmental Protection Agency’s current maximum contaminant level (MCL) of 5 μg/L during the period November 1957–February 1987. At the Hadnot Point WTP, reconstructed trichloroethylene (TCE) concentrations reached a maximum monthly average value of 783 μg/L compared to a one-time maximum measured value of 1400 μg/L during the period August 1953–December 1984. The Hadnot Point WTP also provided contaminated drinking water to the Holcomb Boulevard housing area continuously prior to June 1972, when the Holcomb Boulevard WTP came on line (maximum reconstructed TCE concentration of 32 μg/L) and intermittently during the period June 1972–February 1985 (maximum reconstructed TCE concentration of 66 μg/L). Applying the historical reconstruction process to quantify contaminant-specific monthly drinking-water concentrations is advantageous for epidemiological studies when compared to using the classical exposed versus unexposed approach. PMID:28868161
Decision making in noisy bistable systems with time-dependent asymmetry
NASA Astrophysics Data System (ADS)
Nené, Nuno R.; Zaikin, Alexey
2013-01-01
Our work draws special attention to the importance of the effects of time-dependent parameters on decision making in bistable systems. Here, we extend previous studies of the mechanism known as speed-dependent cellular decision making in genetic circuits by performing an analytical treatment of the canonical supercritical pitchfork bifurcation problem with an additional time-dependent asymmetry and control parameter. This model has an analogous behavior to the genetic switch. In the presence of transient asymmetries and fluctuations, slow passage through the critical region in both systems increases substantially the probability of specific decision outcomes. We also study the relevance for attractor selection of reaching maximum values for the external asymmetry before and after the critical region. Overall, maximum asymmetries should be reached at an instant where the position of the critical point allows for compensation of the detrimental effects of noise in retaining memory of the transient asymmetries.
Superconductivity in multiple phases of compressed GeS b2T e4
NASA Astrophysics Data System (ADS)
Greenberg, E.; Hen, B.; Layek, Samar; Pozin, I.; Friedman, R.; Shelukhin, V.; Rosenberg, Y.; Karpovski, M.; Pasternak, M. P.; Sterer, E.; Dagan, Y.; Rozenberg, G. Kh.; Palevski, A.
2017-02-01
Here we report the discovery of superconductivity in multiple phases of the compressed GeS b2T e4 (GST) phase change memory alloy, which has attracted considerable attention for the last decade due to its unusual physical properties with many potential applications. Superconductivity is observed through electrical transport measurements, both for the amorphous (a -GST) and for the crystalline (c -GST) phases. The superconducting critical temperature Tc continuously increases with applied pressure, reaching a maximum Tc=6 K at P =20 GPa for a -GST, whereas the critical temperature of the cubic phase reaches a maximum Tc=8 K at 30 GPa. This material system, exhibiting a superconductor-insulator quantum phase transition, has an advantage over disordered metals since it has a continuous control of the crystal structure and the electronic properties using pressure as an external stimulus.
NASA Astrophysics Data System (ADS)
Remirez, Andria A.; Webster, Robert J.
2016-03-01
Many applications in medicine require flexible surgical manipulators and endoscopes capable of reaching tight curvatures. The maximum curvature these devices can achieve is often restricted either by a strain limit, or by a maximum actuation force that the device's components can tolerate without risking mechanical failure. In this paper we propose the use of precurvature to "bias" the workspace of the device in one direction. Combined with axial shaft rotation, biasing increases the size of the device's workspace, enabling it to reach tighter curvatures than a comparable device without biasing can achieve, while still being able to fully straighten. To illustrate this effect, we describe several example prototype devices which use flexible nitinol strips that can be pushed and pulled to generate bending. We provide a statics model that relates the manipulator curvature to actuation force, and validate it experimentally.
Laser ablation in an ambient gas: Modelling and experiment
NASA Astrophysics Data System (ADS)
Moscicki, Tomasz; Hoffman, Jacek; Szymanski, Zygmunt
2018-02-01
The laser ablation of graphite in ambient argon is studied both experimentally and theoretically in conditions corresponding to the initial conditions of carbon nanotube synthesis by the laser vaporization method. The results of the experiment show that the maximum plasma temperature of 24 000 K is reached 25 ns after the beginning of the laser pulse and decreases to about 4000-4500 K after 10 μs. The maximum electron density of 8 × 1025 m-3 is reached 15 ns from the beginning of the laser pulse. The hydrodynamic model applied shows comparable plasma temperatures and electron densities. The model also replicates well a shock wave and plume confinement—intrinsic features of supersonic flow of the ablated plume in an ambient gas. The results show that the theoretical model can be used to simulate nanosecond laser ablation in an ambient gas from the beginning of the process up to several microseconds.
Energy dependence of CP-violation reach for monochromatic neutrino beam
NASA Astrophysics Data System (ADS)
Bernabéu, José; Espinoza, Catalina
2008-06-01
The ultimate goal of future neutrino facilities is the determination of CP violation in neutrino oscillations. Besides | U (e 3) | ≠ 0, this will require precision experiments with a very intense neutrino source and energy control. With this objective in mind, the creation of monochromatic neutrino beams from the electron capture decay of boosted ions by the SPS of CERN has been proposed. We discuss the capabilities of such a facility as a function of the energy of the boost and the baseline for the detector. We compare the physics potential for two different configurations: (I) γ = 90 and γ = 195 (maximum achievable at present SPS) to Frejus; (II) γ = 195 and γ = 440 (maximum achievable at upgraded SPS) to Canfranc. We conclude that the SPS upgrade to 1000 GeV is important to reach a better sensitivity to CP violation iff it is accompanied by a longer baseline.
There’s plenty of light at the bottom: statistics of photon penetration depth in random media
Martelli, Fabrizio; Binzoni, Tiziano; Pifferi, Antonio; Spinelli, Lorenzo; Farina, Andrea; Torricelli, Alessandro
2016-01-01
We propose a comprehensive statistical approach describing the penetration depth of light in random media. The presented theory exploits the concept of probability density function f(z|ρ, t) for the maximum depth reached by the photons that are eventually re-emitted from the surface of the medium at distance ρ and time t. Analytical formulas for f, for the mean maximum depth 〈zmax〉 and for the mean average depth reached by the detected photons at the surface of a diffusive slab are derived within the framework of the diffusion approximation to the radiative transfer equation, both in the time domain and the continuous wave domain. Validation of the theory by means of comparisons with Monte Carlo simulations is also presented. The results are of interest for many research fields such as biomedical optics, advanced microscopy and disordered photonics. PMID:27256988
Evaluation of pliers' grip spans in the maximum gripping task and sub-maximum cutting task.
Kim, Dae-Min; Kong, Yong-Ku
2016-12-01
A total of 25 males participated to investigate the effects of the grip spans of pliers on the total grip force, individual finger forces and muscle activities in the maximum gripping task and wire-cutting tasks. In the maximum gripping task, results showed that the 50-mm grip span had significantly higher total grip strength than the other grip spans. In the cutting task, the 50-mm grip span also showed significantly higher grip strength than the 65-mm and 80-mm grip spans, whereas the muscle activities showed a higher value at 80-mm grip span. The ratios of cutting force to maximum grip strength were also investigated. Ratios of 30.3%, 31.3% and 41.3% were obtained by grip spans of 50-mm, 65-mm, and 80-mm, respectively. Thus, the 50-mm grip span for pliers might be recommended to provide maximum exertion in gripping tasks, as well as lower maximum-cutting force ratios in the cutting tasks.
Interception of moving objects while walking in children with spastic hemiparetic cerebral palsy.
Ricken, Annieck X C; Savelsbergh, G J P; Bennett, S J
2007-01-15
The purpose of the study was to examine the coordination of reaching and walking behaviour when children with Spastic Hemiparetic Cerebral Palsy (SHCP) intercept an approaching and hence externally-timed object. Using either the impaired or non-impaired arm, children intercepted a ball approaching from a fixed distance with one of three velocities. Each participant's initial starting position was scaled to their maximum walking velocity determined prior to testing; for the medium ball velocity, participants would arrive at the point of interception at the correct time if they walked with their maximum velocity. Children with SHCP adapted their reaching and walking behaviour to the different ball approach velocities. These adaptations were exhibited when using the impaired and non-impaired arm, and resulted in similar outcome performance irrespective of which arm was used. Still, children with SHCP found it necessary to increase trunk movement to compensate for the decreased elbow excursion and a decreased peak velocity of the impaired arm. Children with SHCP exhibited specific adaptations to their altered movement capabilities when performing a behaviourally-realistic task. The provision of an external timing constraint appeared to facilitate both reaching and walking movements and hence could represent a useful technique in rehabilitation.
Size distribution and growth rate of crystal nuclei near critical undercooling in small volumes
NASA Astrophysics Data System (ADS)
Kožíšek, Z.; Demo, P.
2017-11-01
Kinetic equations are numerically solved within standard nucleation model to determine the size distribution of nuclei in small volumes near critical undercooling. Critical undercooling, when first nuclei are detected within the system, depends on the droplet volume. The size distribution of nuclei reaches the stationary value after some time delay and decreases with nucleus size. Only a certain maximum size of nuclei is reached in small volumes near critical undercooling. As a model system, we selected recently studied nucleation in Ni droplet [J. Bokeloh et al., Phys. Rev. Let. 107 (2011) 145701] due to available experimental and simulation data. However, using these data for sample masses from 23 μg up to 63 mg (corresponding to experiments) leads to the size distribution of nuclei, when no critical nuclei in Ni droplet are formed (the number of critical nuclei < 1). If one takes into account the size dependence of the interfacial energy, the size distribution of nuclei increases to reasonable values. In lower volumes (V ≤ 10-9 m3) nucleus size reaches some maximum extreme size, which quickly increases with undercooling. Supercritical clusters continue their growth only if the number of critical nuclei is sufficiently high.
Senior, Lisa A.; Gyves, Matthew C.
2010-01-01
Time-of-travel, dispersion characteristics, and oxygen reaeration coefficients were determined by use of dye and gas tracing for a 2-mile reach of Tacony/Frankford Creek in Philadelphia, southeastern Pennsylvania. The reach frequently has concentrations of dissolved oxygen (DO) below the water-quality standard of 4 milligrams per liter during warm months. Several large combined sewer overflows (CSOs), including one of the largest in Philadelphia (former Wingohocking Creek), discharge to the study reach in this urbanized watershed, affecting water quality and the timing and magnitude of storm peaks. In addition, a dam that commonly results in backwater conditions and reduced natural reaeration is present a few hundred feet from the end of the study reach. Time-of-travel and reaeration data were collected under base-flow conditions in August and September 2009 for three sub-reaches from Roosevelt Boulevard (U.S. Route 1) to Castor Avenue. Determination of traveltimes to the centroid of the dye cloud were needed for calculation of the reaeration coefficients. Results of the dye study in Tacony/Frankford Creek indicate that traveltimes were affected by the presence of man-made structures, such as the large scour hole and pool developed at the outfall of the T14 CSO and the dam, both of which reduce stream velocities. Mean stream velocities during the dye-tracer tests ranged from a maximum of 0.44 to 0.04 foot per second through a large pool. The dispersion efficiency of the stream was determined from relations between normalized unit concentrations to time to peak for use in water-quality modeling. Oxygen reaeration coefficients determined by a constant rate-injection method using propane as the tracer gas were as low as 0.04 unit per hour in a long pool affected by backwater conditions behind a dam. The highest reaeration coefficient was 2.29 units per hour for a steep-gradient reach with multiple winding channels through gravel deposits, just downstream of a large scour pool developed at the outlet of the T14 CSO. Reaeration coefficients determined from the field tracer-gas method were compared to values calculated by two other methods, one that is based on theoretical equations using physical properties of the stream as variables and the other that is based on equations using the timing of measured daily maximum DO concentrations in the stream. Reaeration coefficients from the two alternate methods were most similar to values determined from the field tracer-gas method for the upstream portion of the study reach, characterized by free-flowing riffle and pools. Values of reaeration coefficients determined by the tracer-gas method were 2 to 10 times higher than values determined by 2 alternate methods for most subreaches hydraulically affected by man-made structures. In addition to the tracer gas, propane, the gas analysis also included methane, ethane, and ethene, of which only methane was measured in concentrations above a few micrograms per liter. Methane, thought to occur naturally or because of ongoing processes in the stream, was measured in concentrations ranging from 6.6 to 78 micrograms per liter; the concentrations were greatest in sub-reaches dominated by pools.
Maximum Range of a Projectile Thrown from Constant-Speed Circular Motion
NASA Astrophysics Data System (ADS)
Poljak, Nikola
2016-11-01
The problem of determining the angle θ at which a point mass launched from ground level with a given speed v0 will reach a maximum distance is a standard exercise in mechanics. There are many possible ways of solving this problem, leading to the well-known answer of θ = π/4, producing a maximum range of D max = v0 2 / g , with g being the free-fall acceleration. Conceptually and calculationally more difficult problems have been suggested to improve student proficiency in projectile motion, with the most famous example being the Tarzan swing problem. The problem of determining the maximum distance of a point mass thrown from constant-speed circular motion is presented and analyzed in detail in this text. The calculational results confirm several conceptually derived conclusions regarding the initial throw position and provide some details on the angles and the way of throwing (underhand or overhand) that produce the maximum throw distance.
Output of skeletal muscle contractions. a study of isokinetic plantar flexion in athletes.
Fugl-Meyer, A R; Mild, K H; Hörnsten, J
1982-06-01
Maximum torques, total work and mean power of isokinetic plantar flexions were measured with simultaneous registrations. The integrated electromyograms (iEMG) were obtained by surface electrodes from all three heads of the m. triceps surae. The method applied offers possibilities for adequate description of dynamic muscular work which in the case of plantar flexion in trained man declines as a negative exponential function of angular motion velocity. The decline is parallel to that of maximum torques. The summed triceps surae iEMG was inversely proportional to the velocity and direct proportional to time suggesting that structural rather than neural factors determine the relationships between velocity of angular motion and maximum torque/total work of single Mmaneuvers. Moreover, the fact that maximum mean power as well as maximum electrical efficiency were reached at the functional velocity of toe-off during gait suggests an influence of pragmatic demands on plantar flexion mechanical output.
Chen, Hu; Liu, Jing; Li, Hong; Ge, Wenqi; Sun, Yuchun; Wang, Yong; Lü, Peijun
2015-02-01
The objective was to study the relationship between laser fluence and ablation efficiency of a femtosecond laser with a Gaussian-shaped pulse used to ablate dentin and enamel for prosthodontic tooth preparation. A diode-pumped thin-disk femtosecond laser with wavelength of 1025 nm and pulse width of 400 fs was used for the ablation of dentin and enamel. The laser spot was guided in a line on the dentin and enamel surfaces to form a groove-shaped ablation zone under a series of laser pulse energies. The width and volume of the ablated line were measured under a three-dimensional confocal microscope to calculate the ablation efficiency. Ablation efficiency for dentin reached a maximum value of 0.020 mm3∕J when the laser fluence was set at 6.51 J∕cm2. For enamel, the maximum ablation efficiency was 0.009 mm3∕J at a fluence of 7.59 J∕cm2.Ablation efficiency of the femtosecond laser on dentin and enamel is closely related to the laser fluence and may reach a maximum when the laser fluence is set to an appropriate value. © 2015 Society of Photo-Optical Instrumentation Engineers (SPIE)
Balbi, C; Abelmoschi, M L; Roner, R; Giaretti, W; Parodi, S; Santi, L
1985-11-01
DNA damage induced in vivo by the cross-linking agent mitomycin C (MMC) was investigated with a new oscillating crucible viscometer. Viscosity was measured by lysing rat liver nuclei in an alkaline lysing solution (pH 12.5; 25 degrees C). In control samples the viscosity increased very slowly with time, reaching a plateau only after 10-12 h. The process was accelerated and the maximum viscosity was decreased by alkaline single-stranded breaks arising from methylation and subsequent depurination of DNA in vitro with dimethylsulphate (DMS). MMC, when given alone, had no evident effect on the time needed for reaching plateau viscosity but it induced a small increase in maximum viscosity. When MMC was given in association with DMS, the time of disentanglement remained unchanged (accelerated) but maximum viscosity was increased in a dose dependent way. We conclude that these data clearly confirm that the slow steady increase of the viscosity of control DNA with time reflects mainly the process of unwinding of the two strands. The speed of this process seems to depend only from the number of unwinding points in DNA (breaks).
Physiological, Nutritional and Performance Profiles of Brazilian Jiu-Jitsu Athletes
Santos, Jonatas FS; Esteves, João VDC; Panissa, Valeria LG; Julio, Ursula F; Franchini, Emerson
2016-01-01
Abstract This study analysed the physiological, nutritional and performance profiles of athletes practicing Brazilian jiu-jitsu. To this end, 15 athletes that practiced Brazilian jiu-jitsu (aged: 28 ± 5 years; 8 brown belts and 7 black belts; training experience: 11 ± 4 years) underwent anthropometric measurements (body composition and somatotype), dietary evaluation (24 h recall) and physical fitness tests (movement time, dynamometer handgrip, kimono grip strength, vertical jump and sit-and-reach tests). The athletes had 12.7 ± 4.8% of body fat, 59.2 ± 5.0% of muscle mass and their somatotype was dominated by the mesomorphic component (5.3 ± 2.0), followed by endomorphic (3.7 ± 1.5) and ectomorphic (1.4 ± 0.9) components. Nutritional assessment suggested a diet consisting of 54 ± 7% of carbohydrates, 19 ± 4% of protein and 27 ± 6% of lipids. Movement time on the handgrip tests was 0.42 ± 0.05 s, for handgrip strength, 53 ± 7 kgf was found for the dominant hand and 50 ± 9 kgf for the non-dominant hand. For the countermovement jump, the jiu-jitsu athletes reached 41 ± 5 cm. Athletes remained 30 ± 14 s in the maximum static suspension test gripping a kimono, and reached 27 ± 8 cm in the sit-and-reach test. Overall the sample presented average levels of body fat, elevated muscle mass and a predominantly mesomorphic somatotype. Diet was generally poor, with low carbohydrate intake, high protein intake and adequate lipid intake. Maximum isometric handgrip strength was consistent with observations of other athletes in this sport discipline. However, the performance in the maximum static suspension test gripping a kimono was lower than in other Brazilian jiu-jitsu athletes. Movement time was comparable and lower body muscle power was worse compared to athletes in similar sports. Additionally, flexibility was rated as poor. PMID:28149429
Physiological, Nutritional and Performance Profiles of Brazilian Jiu-Jitsu Athletes.
Andreato, Leonardo V; Santos, Jonatas Fs; Esteves, João Vdc; Panissa, Valeria Lg; Julio, Ursula F; Franchini, Emerson
2016-12-01
This study analysed the physiological, nutritional and performance profiles of athletes practicing Brazilian jiu-jitsu. To this end, 15 athletes that practiced Brazilian jiu-jitsu (aged: 28 ± 5 years; 8 brown belts and 7 black belts; training experience: 11 ± 4 years) underwent anthropometric measurements (body composition and somatotype), dietary evaluation (24 h recall) and physical fitness tests (movement time, dynamometer handgrip, kimono grip strength, vertical jump and sit-and-reach tests). The athletes had 12.7 ± 4.8% of body fat, 59.2 ± 5.0% of muscle mass and their somatotype was dominated by the mesomorphic component (5.3 ± 2.0), followed by endomorphic (3.7 ± 1.5) and ectomorphic (1.4 ± 0.9) components. Nutritional assessment suggested a diet consisting of 54 ± 7% of carbohydrates, 19 ± 4% of protein and 27 ± 6% of lipids. Movement time on the handgrip tests was 0.42 ± 0.05 s, for handgrip strength, 53 ± 7 kgf was found for the dominant hand and 50 ± 9 kgf for the non-dominant hand. For the countermovement jump, the jiu-jitsu athletes reached 41 ± 5 cm. Athletes remained 30 ± 14 s in the maximum static suspension test gripping a kimono, and reached 27 ± 8 cm in the sit-and-reach test. Overall the sample presented average levels of body fat, elevated muscle mass and a predominantly mesomorphic somatotype. Diet was generally poor, with low carbohydrate intake, high protein intake and adequate lipid intake. Maximum isometric handgrip strength was consistent with observations of other athletes in this sport discipline. However, the performance in the maximum static suspension test gripping a kimono was lower than in other Brazilian jiu-jitsu athletes. Movement time was comparable and lower body muscle power was worse compared to athletes in similar sports. Additionally, flexibility was rated as poor.
[Foliar water use efficiency of Platycladus orientalis sapling under different soil water contents].
Zhang, Yong E; Yu, Xin Xiao; Chen, Li Hua; Jia, Guo Dong; Zhao, Na; Li, Han Zhi; Chang, Xiao Min
2017-07-18
The determination of plant foliar water use efficiency will be of great value to improve our understanding about mechanism of plant water consumption and provide important basis of regional forest ecosystem management and maintenance, thus, laboratory controlled experiments were carried out to obtain Platycladus orientalis sapling foliar water use efficiency under five different soil water contents, including instantaneous water use efficiency (WUE gs ) derived from gas exchange and short-term water use efficiency (WUE cp ) caculated using carbon isotope model. The results showed that, controlled by stomatal conductance (g s ), foliar net photosynthesis rate (P n ) and transpiration rate (T r ) increased as soil water content increased, which both reached maximum va-lues at soil water content of 70%-80% field capacity (FC), while WUE gs reached a maximum of 7.26 mmol·m -2 ·s -1 at the lowest soil water content (35%-45% FC). Both δ 13 C of water-soluble leaf and twig phloem material achieved maximum values at the lowest soil water content (35%-45% FC). Besides, δ 13 C values of leaf water-soluble compounds were significantly greater than that of phloem exudates, indicating that there was depletion in 13 C in twig phloem compared with leaf water-soluble compounds and no obvious fractionation in the process of water-soluble material transportation from leaf to twig. Foliar WUE cp also reached a maximum of 7.26 mmol·m -2 ·s -1 at the lowest soil water content (35%-45% FC). There was some difference between foliar WUE gs and WUE cp under the same condition, and the average difference was 0.52 mmol·m -2 ·s -1 . The WUE gs had great space-time variability, by contrast, WUE cp was more representative. It was concluded that P. orientalis sapling adapted to drought condition by increasing water use efficiency and decreasing physiological activity.
Modeling Food Delivery Dynamics For Juvenile Salmonids Under Variable Flow Regimes
NASA Astrophysics Data System (ADS)
Harrison, L.; Utz, R.; Anderson, K.; Nisbet, R.
2010-12-01
Traditional approaches for assessing instream flow needs for salmonids have typically focused on the importance of physical habitat in determining fish habitat selection. This somewhat simplistic approach does not account for differences in food delivery rates to salmonids that arise due to spatial variability in river morphology, hydraulics and temporal variations in the flow regime. Explicitly linking how changes in the flow regime influences food delivery dynamics is an important step in advancing process-based bioenergetic models that seek to predict growth rates of salmonids across various life-stages. Here we investigate how food delivery rates for juvenile salmonids vary both spatially and with flow magnitude in a meandering reach of the Merced River, CA. We utilize a two-dimensional (2D) hydrodynamic model and discrete particle tracking algorithm to simulate invertebrate drift transport rates at baseflow and a near-bankfull discharge. Modeling results indicate that at baseflow, the maximum drift density occurs in the channel thalweg, while drift densities decrease towards the channel margins due to the process of organisms settling out of the drift. During high-flow events, typical of spring dam-releases, the invertebrate drift transport pathway follows a similar trajectory along the high velocity core and the drift concentrations are greatest in the channel centerline, though the zone of invertebrate transport occupies a greater fraction of the channel width. Based on invertebrate supply rates alone, feeding juvenile salmonids would be expected to be distributed down the channel centerline where the maximum predicted food delivery rates are located in this reach. However, flow velocities in these channel sections are beyond maximum sustainable swimming speeds for most juvenile salmonids. Our preliminary findings suggest that a lack of low velocity refuge may prevent juvenile salmonids from deriving energy from the areas with maximum drift density in this reach. Future efforts will focus on integration of food delivery and bioenergetic models to account for conflicting demands of maximizing food intake while minimizing the energetic costs of swimming.
Anis, Aslam H; Guh, Daphne P; Lacaille, Diane; Marra, Carlo A; Rashidi, Amir A; Li, Xin; Esdaile, John M
2005-11-22
Previous research has shown that patient cost-sharing leads to a reduction in overall health resource utilization. However, in Canada, where health care is provided free of charge except for prescription drugs, the converse may be true. We investigated the effect of prescription drug cost-sharing on overall health care utilization among elderly patients with rheumatoid arthritis. Elderly patients (> or = 65 years) were selected from a population-based cohort with rheumatoid arthritis. Those who had paid the maximum amount of dispensing fees (200 dollars) for the calendar year (from 1997 to 2000) were included in the analysis for that year. We defined the period during which the annual maximum co-payment had not been reached as the "cost-sharing period" and the one beyond which the annual maximum co-payment had been reached as the "free period." We compared health services utilization patterns between these periods during the 4 study years, including the number of hospital admissions, the number of physician visits, the number of prescriptions filled and the number of prescriptions per physician visit. Overall, 2968 elderly patients reached the annual maximum cost-sharing amount at least once during the study periods. Across the 4 years, there were 0.38 more physician visits per month (p < 0.001), 0.50 fewer prescriptions filled per month (p = 0.001) and 0.52 fewer prescriptions filled per physician visit (p < 0.001) during the cost-sharing period than during the free period. Among patients who were admitted to the hospital at least once, there were 0.013 more admissions per month during the cost-sharing period than during the free period (p = 0.03). In a predominantly publicly funded health care system, the implementation of cost-containment policies such as prescription drug cost-sharing may have the unintended effect of increasing overall health utilization among elderly patients with rheumatoid arthritis.
NASA Astrophysics Data System (ADS)
Lee, Ji-Seok; Song, Ki-Won
2015-11-01
The objective of the present study is to systematically elucidate the time-dependent rheological behavior of concentrated xanthan gum systems in complicated step-shear flow fields. Using a strain-controlled rheometer (ARES), step-shear flow behaviors of a concentrated xanthan gum model solution have been experimentally investigated in interrupted shear flow fields with a various combination of different shear rates, shearing times and rest times, and step-incremental and step-reductional shear flow fields with various shearing times. The main findings obtained from this study are summarized as follows. (i) In interrupted shear flow fields, the shear stress is sharply increased until reaching the maximum stress at an initial stage of shearing times, and then a stress decay towards a steady state is observed as the shearing time is increased in both start-up shear flow fields. The shear stress is suddenly decreased immediately after the imposed shear rate is stopped, and then slowly decayed during the period of a rest time. (ii) As an increase in rest time, the difference in the maximum stress values between the two start-up shear flow fields is decreased whereas the shearing time exerts a slight influence on this behavior. (iii) In step-incremental shear flow fields, after passing through the maximum stress, structural destruction causes a stress decay behavior towards a steady state as an increase in shearing time in each step shear flow region. The time needed to reach the maximum stress value is shortened as an increase in step-increased shear rate. (iv) In step-reductional shear flow fields, after passing through the minimum stress, structural recovery induces a stress growth behavior towards an equilibrium state as an increase in shearing time in each step shear flow region. The time needed to reach the minimum stress value is lengthened as a decrease in step-decreased shear rate.
Numerical Simulation of the Nozzle and Test Section of a Mach 6 Ludwieg Tube
2013-06-24
B. Condensation Condensation is a phenomenon where the test gas is changi ng into a solid form without ever having been a liquid . It happens for...reaches a maximum value at the throat. But with a sonic throat. the speed continues to increase in the nozzle and reaches supersonic and hypersonic...the three curves join. These curves are the gas -solid. gas - liquid and solid- liquid boundaries (solid- liquid boundaries arc not representing here
Distillation time effect on lavender essential oil yield and composition.
Zheljazkov, Valtcho D; Cantrell, Charles L; Astatkie, Tess; Jeliazkova, Ekaterina
2013-01-01
Lavender (Lavandula angustifolia Mill.) is one of the most widely grown essential oil crops in the world. Commercial extraction of lavender oil is done using steam distillation. The objective of this study was to evaluate the effect of the length of the distillation time (DT) on lavender essential oil yield and composition when extracted from dried flowers. Therefore, the following distillation times (DT) were tested in this experiment: 1.5 min, 3 min, 3.75 min, 7.5 min, 15 min, 30 min, 60 min, 90 min, 120 min, 150 min, 180 min, and 240 min. The essential oil yield (range 0.5-6.8%) reached a maximum at 60 min DT. The concentrations of cineole (range 6.4-35%) and fenchol (range 1.7-2.9%) were highest at the 1.5 min DT and decreased with increasing length of the DT. The concentration of camphor (range 6.6-9.2%) reached a maximum at 7.5-15 min DT, while the concentration of linalool acetate (range 15-38%) reached a maximum at 30 min DT. Results suggest that lavender essential oil yield may not increase after 60 min DT. The change in essential oil yield, and the concentrations of cineole, fenchol and linalool acetate as DT changes were modeled very well by the asymptotic nonlinear regression model. DT may be used to modify the chemical profile of lavender oil and to obtain oils with differential chemical profiles from the same lavender flowers. DT must be taken into consideration when citing or comparing reports on lavender essential oil yield and composition.
Agrometeorological parameters for prediction of the maturation period of Arabica coffee cultivars
NASA Astrophysics Data System (ADS)
Pezzopane, José Ricardo Macedo; Salva, Terezinha de Jesus Garcia; de Lima, Valéria Bittencourt; Fazuoli, Luiz Carlos
2012-09-01
The objective of this study was to determine the harvest period of coffee fruits based on the relationship between agrometeorological parameters and sucrose accumulation in the seeds. Over the crop years 2004/2005 and 2006/2007, from 150 days after flowering (DAF) onwards, samples of 50 fruits of cultivars Mundo Novo IAC 376-4, Obatã IAC 1669-20 and Catuaí Vermelho IAC 144 were collected from coffee trees located in Campinas, Brazil. The endosperm of the fruits was freeze-dried, ground and analyzed for sucrose content by high-performance liquid chromatography. A weather station provided data to calculate the accumulated growing degree-day (GDD) units, and the reference (ETo) and actual (ETr) evapotranspiration rates. The results showed that the highest rates of sucrose accumulation occurred at the transition from the cane-green to the cherry phenological stage. Models for the estimation of sucrose content during maturation based on meteorological variables exhibited similar or better performance than the DAF variable, with better results for the variables GDD and ETo. The Mundo Novo cultivar reached the highest sucrose level in the endosperm after 2,790 GDD, while cultivar Catuaí attained its maximum sucrose concentration after the accumulated evapotranspiration rate has reached a value of 870 mm. As for cultivar Obatã, the maximum sucrose concentration was predicted with the same degree of accuracy using any of the parameters investigated. For the Obatã cultivar, the values of the variables calculated for the maximum sucrose concentration to be reached were 249 DAF, 3,090 GDD, 1,020 ETo and 900 ETr.
Strandbygaard, Jeanett; Bjerrum, Flemming; Maagaard, Mathilde; Winkel, Per; Larsen, Christian Rifbjerg; Ringsted, Charlotte; Gluud, Christian; Grantcharov, Teodor; Ottesen, Bent; Sorensen, Jette Led
2013-05-01
To investigate the impact of instructor feedback versus no instructor feedback when training a complex operational task on a laparoscopic virtual reality simulator. : Simulators are now widely accepted as a training tool, but there is insufficient knowledge about how much feedback is necessary, which is useful for sustainable implementation. A randomized trial complying with CONSORT Statement. All participants had to reach a predefined proficiency level for a complex operational task on a virtual reality simulator. The intervention group received standardized instructor feedback a maximum of 3 times. The control group did not receive instructor feedback. Participants were senior medical students without prior laparoscopic experience (n = 99). Outcome measures were time, repetitions, and performance score to reach a predefined proficiency level. Furthermore, influence of sex and perception of own surgical skills were examined. Time (in minutes) and repetitions were reduced in the intervention group (162 vs 342 minutes; P < 0.005) and (29 vs 65 repetitions; P < 0.005). The control group achieved a higher performance score than the intervention group (57% vs 49%; P = 0.004). Men used less time (in minutes) than women (P = 0.037), but no sex difference was observed for repetitions (P = 0.20). Participants in the intervention group had higher self-perception regarding surgical skills after the trial (P = 0.011). Instructor feedback increases the efficiency when training a complex operational task on a virtual reality simulator; time and repetitions used to achieve a predefined proficiency level were significantly reduced in the group that received instructor feedback compared with the control group. NCT01497782.
Huguenot, David; Mousset, Emmanuel; van Hullebusch, Eric D; Oturan, Mehmet A
2015-04-15
In order to improve the efficiency of soil washing treatment of hydrocarbon contaminated soils, an innovative combination of this soil treatment technique with an electrochemical advanced oxidation process (i.e. electro-Fenton (EF)) has been proposed. An ex situ soil column washing experiment was performed on a genuinely diesel-contaminated soil. The washing solution was enriched with surfactant Tween 80 at different concentrations, higher than the critical micellar concentration (CMC). The impact of soil washing was evaluated on the hydrocarbons concentration in the leachates collected at the bottom of the soil columns. These eluates were then studied for their degradation potential by EF treatment. Results showed that a concentration of 5% of Tween 80 was required to enhance hydrocarbons extraction from the soil. Even with this Tween 80 concentration, the efficiency of the treatment remained very low (only 1% after 24 h of washing). Electrochemical treatments performed thereafter with EF on the collected eluates revealed that the quasi-complete mineralization (>99.5%) of the hydrocarbons was achieved within 32 h according to a linear kinetic trend. Toxicity was higher than in the initial solution and reached 95% of inhibition of Vibrio fischeri bacteria measured by Microtox method, demonstrating the presence of remaining toxic compounds even after the complete degradation. Finally, the biodegradability (BOD₅/COD ratio) reached a maximum of 20% after 20 h of EF treatment, which is not enough to implement a combined treatment with a biological treatment process. Copyright © 2015 Elsevier Ltd. All rights reserved.
Dolph, Christine L.; Eggert, Susan L.; Magner, Joe; Ferrington, Leonard C.; Vondracek, Bruce C.
2015-01-01
Recent studies suggest that stream restoration at the reach scale may not increase stream biodiversity, raising concerns about the utility of this conservation practice. We examined whether reach-scale restoration in disturbed agricultural streams was associated with changes in macroinvertebrate community structure (total macroinvertebrate taxon richness, total macroinvertebrate density, Ephemeroptera, Plecoptera, Trichoptera [EPT] taxon richness, % abundance of EPT taxa) or secondary production (macroinvertebrate biomass over time). We collected macroinvertebrate samples over the course of 1 y from restored and unrestored reaches of 3 streams in southern Minnesota and used generalized least-square (GLS) models to assess whether measures of community structure were related to reach type, stream site, or sampling month. After accounting for effects of stream site and time, we found no significant difference in total taxon richness or % abundance of EPT taxa between restored and unrestored reaches. However, the number of EPT taxa and macroinvertebrate density were significantly higher in restored than in unrestored reaches. We compared secondary production estimates among study reaches based on 95th-percentile confidence intervals generated via bootstrapping. In each study stream, secondary production was significantly (2–3×) higher in the restored than in the unrestored reach. Higher productivity in the restored reaches was largely a result of the disproportionate success of a few dominant, tolerant taxa. Our findings suggest that reach-scale restoration may have ecological effects that are not detected by measures of total taxon richness alone.
Extreme waves under Hurricane Ivan.
Wang, David W; Mitchell, Douglas A; Teague, William J; Jarosz, Ewa; Hulbert, Mark S
2005-08-05
Hurricane Ivan, a category 4 storm, passed directly over six wave-tide gauges deployed by the Naval Research Laboratory on the outer continental shelf in the northeastern Gulf of Mexico. Waves were observed with significant wave heights reaching 17.9 meters and maximum crest-to-trough individual wave heights of 27.7 meters (91 feet). Analysis suggests that significant wave heights likely surpassed 21 meters (69 feet) and that maximum crest-to-trough individual wave heights exceeded 40 meters (132 feet) near the eyewall.
Indoor radon survey in Visegrad countries.
Műllerová, Monika; Kozak, Krzysztof; Kovács, Tibor; Smetanová, Iveta; Csordás, Anita; Grzadziel, Dominik; Holý, Karol; Mazur, Jadwiga; Moravcsík, Attila; Neznal, Martin; Neznal, Matej
2016-04-01
The indoor radon measurements were carried out in 123 residential buildings and 33 schools in Visegrad countries (Slovakia, Hungary and Poland). In 13.2% of rooms radon concentration exceeded 300Bqm(-3), the reference value recommended in the Council Directive 2013/59/EURATOM. Indoor radon in houses shows the typical radon behavior, with a minimum in the summer and a maximum in the winter season, whereas in 32% of schools the maximum indoor radon was reached in the summer months. Copyright © 2016 Elsevier Ltd. All rights reserved.
André, Nuno Sequeira; Habel, Kai; Louchet, Hadrien; Richter, André
2013-11-04
We report experimental validations of an adaptive 2nd order Volterra equalization scheme for cost effective IMDD OFDM systems. This equalization scheme was applied to both uplink and downlink transmission. Downlink settings were optimized for maximum bitrate where we achieved 34 Gb/s over 10 km of SSMF using an EML with 10 GHz bandwidth. For the uplink, maximum reach was optimized achieving 14 Gb/s using a low-cost DML with 2.5 GHz bandwidth.
1989-07-01
The largest of the teeth on vomer or palatines . surfperches, reaching a maximum length Branchiostegals 5-6; gill membranes of 47 cm TL (Eschmeyer et...Fritzsche 1982). dorsal surface. Fins dusky (Tarp 1952). Maximum length 44 cm total length (TL) (Eschmeyer et al. 1983). LIFE HISTORY Embiotoca lateralis...developed, shore. From 1958 to 1961, sport fused pharyngeal tooth plates that fishermen caught an estimated 5,000 enable the fish to crush hard-shelled
Flood Summary Report, Nooksack, Skagit and Snohomish River Basins November 1990 Events
1991-07-18
1990. Rivers throughout mid-western Washington flooded, with the Snohomish, Cedar, Skagit, and Wenatchee rivers reaching or exceeding their previous...which is equivalent to a 70-year event, and is the new maximum of record. The Wenatchee River at Peshastin crested at 17.6 feet on 25 November. Maximum...AD-A242 469 CNSE Seattle District D1JUY 91 FLOOD SUMMARY REPORT NOOKSACK, SKAGIT AND SNOHOMISH RIVER BASINS NOVEMBER 1990 EVENTS 11l1lfll9 114fd
Sánchez-Gómez, David; Valladares, Fernando; Zavala, Miguel A
2006-11-01
We investigated the differential roles of physiological and morphological features on seedling survivorship along an experimental irradiance gradient in four dominant species of cool temperate-Mediterranean forests (Quercus robur L., Quercus pyrenaica Willd., Pinus sylvestris L. and Pinus pinaster Ait.). The lowest photochemical efficiency (F(v)/F(m) in dark-adapted leaves) was reached in deep shade (1% of full sunlight) in all species except Q. robur, which had the lowest photochemical efficiency in both deep shade and 100% of full sunlight. Species differed significantly in their survival in 1% of full sunlight but exhibited similar survivorship in 6, 20 and 100% of full sunlight. Shade-tolerant oaks had lower leaf area ratios, shoot to root ratios, foliage allocation ratios and higher rates of allocation to structural biomass (stem plus thick roots) than shade-intolerant pines. Overall phenotypic plasticity for each species, estimated as the difference between the minimum and the maximum mean values of the ecophysiological variables studied at the various irradiances divided by the maximum mean value of those variables, was inversely correlated with shade tolerance. Observed morphology, allocation and plasticity conformed to a conservative resource-use strategy, although observed differences in specific leaf area, which was higher in shade-tolerant species, supported a carbon gain maximization strategy. Lack of a congruent suite of traits underlying shade tolerance in the studied species provides evidence of adaptation to multiple selective forces. Although the study was based on only four species, the importance of ecophysiological variables as determinants of interspecific differences in survival in limiting light was demonstrated.
Analysis of flow patterns in a patient-specific aortic dissection model.
Cheng, Z; Tan, F P P; Riga, C V; Bicknell, C D; Hamady, M S; Gibbs, R G J; Wood, N B; Xu, X Y
2010-05-01
Aortic dissection is the most common acute catastrophic event affecting the thoracic aorta. The majority of patients presenting with an uncomplicated type B dissection are treated medically, but 25% of these patients develop subsequent aneurysmal dilatation of the thoracic aorta. This study aimed at gaining more detailed knowledge of the flow phenomena associated with this condition. Morphological features and flow patterns in a dissected aortic segment of a presurgery type B dissection patient were analyzed based on computed tomography images acquired from the patient. Computational simulations of blood flow in the patient-specific model were performed by employing a correlation-based transitional version of Menter's hybrid k-epsilon/k-omega shear stress transport turbulence model implemented in ANSYS CFX 11. Our results show that the dissected aorta is dominated by locally highly disturbed, and possibly turbulent, flow with strong recirculation. A significant proportion (about 80%) of the aortic flow enters the false lumen, which may further increase the dilatation of the aorta. High values of wall shear stress have been found around the tear on the true lumen wall, perhaps increasing the likelihood of expanding the tear. Turbulence intensity in the tear region reaches a maximum of 70% at midsystolic deceleration phase. Incorporating the non-Newtonian behavior of blood into the same transitional flow model has yielded a slightly lower peak wall shear stress and higher maximum turbulence intensity without causing discernible changes to the distribution patterns. Comparisons between the laminar and turbulent flow simulations show a qualitatively similar distribution of wall shear stress but a significantly higher magnitude with the transitional turbulence model.
Lindane removal by pure and mixed cultures of immobilized actinobacteria.
Saez, Juliana M; Benimeli, Claudia S; Amoroso, María J
2012-11-01
Lindane (γ-HCH) is an organochlorine insecticide that has been widely used in developing countries. It is known to persist in the environment and can cause serious health problems. One of the strategies adopted to remove lindane from the environment is bioremediation using microorganisms. Immobilized cells present advantages over free suspended cells, like their high degradation efficiency and protection against toxins. The aims of this work were: (1) To evaluate the ability of Streptomyces strains immobilized in four different matrices to remove lindane, (2) To select the support with optimum lindane removal by pure cultures, (3) To assay the selected support with consortia and (4) To evaluate the reusability of the immobilized cells. Four Streptomyces sp. strains had previously shown their ability to grow in the presence of lindane. Lindane removal by microorganisms immobilized was significantly higher than in free cells. Specifically immobilized cells in cloth sachets showed an improvement of around 25% in lindane removal compared to the abiotic control. Three strains showed significantly higher microbial growth when they were entrapped in silicone tubes. Strains immobilized in PVA-alginate demonstrated lowest growth. Mixed cultures immobilized inside cloth sachets showed no significant enhancement compared to pure cultures, reaching a maximum removal of 81% after 96 h for consortium I, consisting of the four immobilized strains together. Nevertheless, the cells could be reused for two additional cycles of 96 h each, obtaining a maximum removal efficiency of 71.5% when each of the four strains was immobilized in a separate bag (consortium III). Copyright © 2012 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Dawid, Rys; Piotr, Jaskula
2018-05-01
Oversized heavy duty vehicles occur in traffic very rarely but they reach extremely high weights, even up to 800 tonne. The detrimental impact of these vehicles on pavement structure is much higher than in case of commercial vehicles that comprise typical traffic, thus it is necessary to assess the sensitivity of pavement structure to passage of oversized vehicles. The paper presents results of sample calculations of load equivalency factor of a heavy duty oversized vehicle with usage of mechanistic-empirical approach. The effects of pavement thickness, type of distress (cracking or rutting) and pavement condition (new or old with structural damage) were considered in the paper. Analysis revealed that a single pass of an 800 tonne oversized vehicle is equivalent to pass of up to 377 standard 100 kN axles. Load equivalency factor calculated for thin structures is almost 3 times lower than for thick structures, however, the damage effect caused by one pass of an oversized vehicle is higher in the case of thin structure. Bearing capacity of a pavement structure may be qualified as sufficient for passage of an oversized heavy duty vehicle when the measured deflection, for example in an FWD test, does not exceed the maximum deflections derived from mechanistic-empirical analysis. The paper presents sample calculation of maximum deflections which allow to consider passage of an oversized vehicle as safe over different pavement structures. The paper provides road administration with a practical tool which helps to decide whether to issue a permit of passage for a given oversized vehicle.
Temperature and Precipitation trends in Kashmir valley, North Western Himalayas
NASA Astrophysics Data System (ADS)
Shafiq, Mifta Ul; Rasool, Rehana; Ahmed, Pervez; Dimri, A. P.
2018-01-01
Climate change has emerged as an important issue ever to confront mankind. This concern emerges from the fact that our day-to-day activities are leading to impacts on the Earth's atmosphere that has the potential to significantly alter the planet's shield and radiation balance. Developing countries particularly whose income is particularly derived from agricultural activities are at the forefront of bearing repercussions due to changing climate. The present study is an effort to analyze the changing trends of precipitation and temperature variables in Kashmir valley along different elevation zones in the north western part of India. As the Kashmir valley has a rich repository of glaciers with its annual share of precipitation, slight change in the temperature and precipitation regime has far reaching environmental and economic consequences. The results from Indian Meteorological Department (IMD) data of the period 1980-2014 reveals that the annual mean temperature of Kashmir valley has increased significantly. Accelerated warming has been observed during 1980-2014, with intense warming in the recent years (2001-2014). During the period 1980-2014, steeper increase, in annual mean maximum temperature than annual mean minimum temperature, has been observed. In addition, mean maximum temperature in plain regions has shown higher rate of increase when compared with mountainous areas. In case of mean minimum temperature, mountainous regions have shown higher rate of increase. Analysis of precipitation data for the same period shows a decreasing trend with mountainous regions having the highest rate of decrease which can be quite hazardous for the fragile mountain environment of the Kashmir valley housing a large number of glaciers.
Biscarini, Andrea; Benvenuti, Paolo; Botti, Fabio M; Brunetti, Antonella; Brunetti, Orazio; Pettorossi, Vito E
2014-09-01
A number of research studies provide evidence that hamstring cocontraction during open kinetic chain knee extension exercises enhances tibiofemoral (TF) stability and reduces the strain on the anterior cruciate ligament. To determine the possible increase in hamstring muscle coactivation caused by a voluntary cocontraction effort during open kinetic chain leg-extension exercises, and to assess whether an intentional hamstring cocontraction can completely suppress the anterior TF shear force during these exercises. Descriptive laboratory study. Knee kinematics as well as electromyographic activity in the semitendinosus (ST), semimembranosus (SM), biceps femoris (BF), and quadriceps femoris muscles were measured in 20 healthy men during isotonic leg extension exercises with resistance (R) ranging from 10% to 80% of the 1-repetition maximum (1RM). The same exercises were also performed while the participants attempted to enhance hamstring coactivation through a voluntary cocontraction effort. The data served as input parameters for a model to calculate the shear and compressive TF forces in leg extension exercises for any set of coactivation patterns of the different hamstring muscles. For R≤ 40% 1RM, the peak coactivation levels obtained with intentional cocontraction (l) were significantly higher (P < 10(-3)) than those obtained without intentional cocontraction (l 0). For each hamstring muscle, maximum level l was reached at R = 30% 1RM, corresponding to 9.2%, 10.5%, and 24.5% maximum voluntary isometric contraction (MVIC) for the BF, ST, and SM, respectively, whereas the ratio l/l 0 reached its maximum at R = 20% 1RM and was approximately 2, 3, and 4 for the BF, SM, and ST, respectively. The voluntary enhanced coactivation level l obtained for R≤ 30% 1RM completely suppressed the anterior TF shear force developed by the quadriceps during the exercise. In leg extension exercises with resistance R≤ 40% 1RM, coactivation of the BF, SM, and ST can be significantly enhanced (up to 2, 3, and 4 times, respectively) by a voluntary hamstring cocontraction effort. The enhanced coactivation levels obtained for R≤ 30% 1RM can completely suppress the anterior TF shear force developed by the quadriceps during the exercise. This laboratory study suggests that leg extension exercise with intentional hamstring cocontraction may have the potential to be a safe and effective quadriceps-strengthening intervention in the early stages of rehabilitation programs for anterior cruciate ligament injury or reconstruction recovery. Further studies, including clinical trials, are needed to investigate the relevance of this therapeutic exercise in clinical practice. © 2014 The Author(s).
Impaired pharmacokinetics of levothyroxine in severely obese volunteers.
Michalaki, Marina A; Gkotsina, Margarita I; Mamali, Irene; Markantes, Georgios K; Faltaka, Amalia; Kalfarentzos, Fotios; Vagenakis, Apostolos G; Markou, Kostas B
2011-05-01
Suppressive or replacement doses of levothyroxine (LT4) are affected by the rate and extent of the active ingredient absorbed, as well as by the lean body mass. Obesity has reached epidemic proportions worldwide and is related with many comorbidities. The aim of this study was to determine the pharmacokinetic parameters of LT4 in severely obese individuals and compared them with similar data in lean control subjects. We studied 62 euthyroid subjects who had negative tests for anti-thyroid peroxidise antibodies (Ab-TPO). Thirty eight of these subjects were severely obese but otherwise healthy (severe obese subjects [SOS] group). Twenty-four were healthy control subjects (control group), with a body mass index of 23.3 ± 1.7 kg/m(2). Subjects received 600 μg oral sodium LT4 after an overnight fast. Serum triiodothyronine (T3), T4, and thyroid-stimulating hormone were measured at baseline. Serum T4 and T3 was measured 0.5, 1, 1.5, 2, 2.5, 3, and 4 hours after LT4 administration. Baseline serum T4 and thyroid-stimulating hormone concentrations were higher in the SOS group than in the control group; serum T3 was similar in the two groups. The corrected area under the curve and the maximum T4 concentration after LT4 administration were lower, whereas the time to maximum concentration from the baseline was higher in SOS than in the control group. The estimated plasma volume was higher in the SOS than in the control group. Mean serum T3 levels increased gradually during the four hours after LT4 administration in the control group. In contrast, they decreased gradually in the SOS group. Severely obese individuals may need higher LT4 suppressive or replacement doses than normal-weight individuals due, among other factors, to impaired LT4 pharmacokinetic parameters. The latter could be attributed to their higher plasma volume and/or to delayed gastrointestinal LT4 absorption. T4 conversion to T3 might be defective in severe obesity.
Mediterranean climate effects. II. Conifer growth phenology across a Sierra Nevada ecotone.
Royce, E B; Barbour, M G
2001-05-01
Growth and xylem water potential of the lower elevation conifers Pinus jeffreyi and Abies concolor and the higher elevation Pinus monticola and Abies magnifica were monitored in their montane Mediterranean habitat of the southernmost Sierra Nevada mountains of California. Measurements were made across the ecotone between the midmontane and upper montane forests and through light and heavy snowfall years.Radial stem growth, averaging ∼1.5 mm/yr, started 2 wk after snow melt, providing that maximum air temperatures had reached 21°C, and ended when predawn water potentials fell rapidly at the onset of the summer drought. Leader growth started on or after a fixed date, providing that minimum air temperatures were above -4°C for Pinus species or +2.5°C for Abies species. The cue for leader growth was inferred to be photoperiodic. Leader growth ended when either a determinate internode length of ∼1 mm was reached or predawn water potentials fell rapidly. Abies magnifica grew more rapidly than the low-elevation species, but had a shorter growth period; its annual leader growth, as a consequence, was only 35 mm/yr vs. 50 mm/yr for the low-elevation species. Needle growth was similarly determinate in the absence of early drought. This growth phenology contributes to determining species distribution across the ecotone.
Qin, Cai-qing; Liang, Li; You, Rui; Deng, Han; Wang, Ding-yong
2015-12-01
To investigate effects of the main component of vegetation root exudates-citric acid on activation and methylation of mercury in the soil of water-level-fluctuating zone (WLFZ) of the Three Gorges Reservoir area, simulation experiments were conducted by extracting and cultivating soil with different concentrations of citric acid. The results showed that after adding citric acid, the total mercury content in leaching solution before reaching peak were higher than that of the control, and increased with the increase of citric acid concentrations. The maximum amount of mercury complexes increased initially and then reached plateaus with the percentage against the total mercury in soil of 1.03%, 1.67%, 1.99%, 2.47%, 2.68%, 2.73% and 2.73% for different citric acid concentrations (0, 1, 2, 4, 5, 6 and 8 mmol · L⁻¹). In addition, concentrations of methylmercury ( MeHg) in soil remained stable in the first 3 hours, and then increased accompanying with the increasing rate rising with the concentration of citric acid ( besides the control group) . This result indicated that citric acid probably could promote the transformation process from inorganic mercury to MeHg in soil. which increased with the concentration of citric acid.
The structural response of the cornea to changes in stromal hydration
White, Tomas; Boote, Craig; Kamma-Lorger, Christina S.; Bell, James; Sorenson, Thomas; Terrill, Nick; Shebanova, Olga; Meek, Keith M.
2017-01-01
The primary aim of this study was to quantify the relationship between corneal structure and hydration in humans and pigs. X-ray scattering data were collected from human and porcine corneas equilibrated with polyethylene glycol (PEG) to varying levels of hydration, to obtain measurements of collagen fibril diameter, interfibrillar spacing (IFS) and intermolecular spacing. Both species showed a strong positive linear correlation between hydration and IFS2 and a nonlinear, bi-phasic relationship between hydration and fibril diameter, whereby fibril diameter increased up to approximately physiological hydration, H = 3.0, with little change thereafter. Above H = 3.0, porcine corneas exhibited a larger fibril diameter than human corneas (p < 0.001). Intermolecular spacing also varied with hydration in a bi-phasic manner but reached a maximum value at a lower hydration (H = 1.5) than fibril diameter. Human corneas displayed a higher intermolecular spacing than porcine corneas at all hydrations (p < 0.0001). Human and porcine corneas required a similar PEG concentration to reach physiological hydration, suggesting that the total fixed charge that gives rise to the swelling pressure is the same. The difference in their structural responses to hydration can be explained by variations in molecular cross-linking and intra/interfibrillar water partitioning. PMID:28592658
Methylmercury-cholinesterase interactions in rats.
Hastings, F L; Lucier, G W; Klein, R
1975-01-01
The interaction of methylmercury hydroxide (MMH) and cholinesterases was studied in male and female rats. MMH administered subcutaneously in doses of 10 mg/kg for 2 days reduced the level of plasma cholinesterase (ButChE) by 68% in females and 47% in males while brain acetylcholinesterase (AChE) was unaffected. Normal females had higher but more variable ButChE levels than normal males. In a time-course experiment, a single dose of MMH (10 mg/kg) reduced ButChE levels when mercury levels reached 22 mug/ml in the blood. A 10% reduction in brain AChE was observed at 72 hours; however, mercury reached a concentration of only 2.0 mug/g in brain tissue. The determination of the Michaelis constant Km and maximum velocity value Vmax for butyrylcholine and ButChE in control and MMH-treated (1 mg/kg) animals indicated that MMH reduced Vmax only. Since no loss in ButChE activity occurred when MMH and control plasma were incubated in vitro, MMH is not a direct inhibitor of ButChE. Because only the inactive monomeric form of ButChE contains free sulfhydryl groups, it is postulated that MMH combines covalently with the sulfur, preventing formation of active enzyme. By analogy, it is believed this is also the case with AChE. PMID:1227853
The structural response of the cornea to changes in stromal hydration.
Hayes, Sally; White, Tomas; Boote, Craig; Kamma-Lorger, Christina S; Bell, James; Sorenson, Thomas; Terrill, Nick; Shebanova, Olga; Meek, Keith M
2017-06-01
The primary aim of this study was to quantify the relationship between corneal structure and hydration in humans and pigs. X-ray scattering data were collected from human and porcine corneas equilibrated with polyethylene glycol (PEG) to varying levels of hydration, to obtain measurements of collagen fibril diameter, interfibrillar spacing (IFS) and intermolecular spacing. Both species showed a strong positive linear correlation between hydration and IFS 2 and a nonlinear, bi-phasic relationship between hydration and fibril diameter, whereby fibril diameter increased up to approximately physiological hydration, H = 3.0, with little change thereafter. Above H = 3.0, porcine corneas exhibited a larger fibril diameter than human corneas ( p < 0.001). Intermolecular spacing also varied with hydration in a bi-phasic manner but reached a maximum value at a lower hydration ( H = 1.5) than fibril diameter. Human corneas displayed a higher intermolecular spacing than porcine corneas at all hydrations ( p < 0.0001). Human and porcine corneas required a similar PEG concentration to reach physiological hydration, suggesting that the total fixed charge that gives rise to the swelling pressure is the same. The difference in their structural responses to hydration can be explained by variations in molecular cross-linking and intra/interfibrillar water partitioning. © 2017 The Authors.
Liu, Huaming; Zhang, Dandan; Tang, Zhidan; Sun, Mengjie; Azietaku, John Teye; Ouyang, Huizi; Chang, Yanxu; Wang, Meng; He, Jun; Gao, Xiumei
2018-05-29
Periplocin is a cardiac glycoside and has been used widely in the clinic for its cardiotonic, anti-inflammatory and anti-tumor effects. Though it was taken frequently by oral administration in clinic, there were no reports demonstrated that periplocin could be detected in vivo after an oral administration of periplocin, so it is badly need of searching the characteristic of periplocin in vivo after an oral administration. In this study, a sensitive and reliable liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated to identify and quantify periplocin and its two metabolites in rat tissue after a single dosage of perplocin at 50 mg/kg. The results demonstrated that periplocin and its two metabolites were detected in all of the selected tissues, periplocin could be reach peak concentration quickly after administration, while periplocymarin and periplogenin reached maximum concentration more than 4.83 h after administration. The tissue distribution of analytes tended to be mostly in the liver, and higher analytes concentrations were found in the heart, liver, spleen, lung, kidney, but a small amount of chemical constituents were distributed into the brain. The consequences obtained using this method might provide a meaningful insight for the clinical investigations and applications. This article is protected by copyright. All rights reserved.
Changes in thickness and surface area of the human cortex and their relationship with intelligence.
Schnack, Hugo G; van Haren, Neeltje E M; Brouwer, Rachel M; Evans, Alan; Durston, Sarah; Boomsma, Dorret I; Kahn, René S; Hulshoff Pol, Hilleke E
2015-06-01
Changes in cortical thickness over time have been related to intelligence, but whether changes in cortical surface area are related to general cognitive functioning is unknown. We therefore examined the relationship between intelligence quotient (IQ) and changes in cortical thickness and surface over time in 504 healthy subjects. At 10 years of age, more intelligent children have a slightly thinner cortex than children with a lower IQ. This relationship becomes more pronounced with increasing age: with higher IQ, a faster thinning of the cortex is found over time. In the more intelligent young adults, this relationship reverses so that by the age of 42 a thicker cortex is associated with higher intelligence. In contrast, cortical surface is larger in more intelligent children at the age of 10. The cortical surface is still expanding, reaching its maximum area during adolescence. With higher IQ, cortical expansion is completed at a younger age; and once completed, surface area decreases at a higher rate. These findings suggest that intelligence may be more related to the magnitude and timing of changes in brain structure during development than to brain structure per se, and that the cortex is never completed but shows continuing intelligence-dependent development. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Draves, J.F.; Fox, M.G.
1998-08-01
In this study, the authors examined the effects of a gold mine tailings spill in the Montreal River (northern Ontario, Canada) on juvenile yellow perch (Perca flavescens), a benthic-feeding fish, and identified the major contributors to their uptake of tailings metals (Pb, Zn, Cd, and Cu) in dietary items and river water. Juvenile perch sampled from a 6-km reach of the river where most of the tailings were deposited had significantly less food in their stomachs than individuals sampled from a reference reach of the river. Concentrations of Pb in invertebrate prey taxa from the contaminated reach were 9 tomore » 20 times higher than in those sampled from the reference reach. These differences were consistent with a higher concentration of Pb in perch from the contaminated reach. In contrast, Zn concentrations were high in river water and perch from both the reference and contaminated reaches, and little difference was found in Zn concentration between invertebrate prey types sampled from the two reaches. No significant differences were found in Cu or Cd concentrations in yellow perch sampled from the two reaches. Higher levels of Pb in the major prey types from the contaminated reach indicate that dietary uptake may be the major vector for Pb accumulation in yellow perch from the Montreal River.« less
On the cosmic ray spectrum from type II supernovae expanding in their red giant presupernova wind
NASA Astrophysics Data System (ADS)
Cardillo, Martina; Amato, Elena; Blasi, Pasquale
2015-09-01
While from the energetic point of view supernova remnants are viable sources of Galactic cosmic rays (CRs), the issue of whether they can accelerate protons up to a few PeV remains unsolved. Here we discuss particle acceleration at the forward shock of supernovae, and discuss the possibility that the current of escaping particles may excite a non-resonant instability that in turn leads to the formation of resonant modes that confine particles close to the shock, thereby increasing the maximum energy. This mechanism is at work throughout the expansion of the supernova explosion, from the ejecta dominated (ED) phase to the Sedov-Taylor (ST) phase. The transition from one stage to the other reflects in a break in the spectrum of injected particles. Because of their higher explosion rate, we focus our work on type II SNe expanding in the slow, dense wind, produced by the red super-giant progenitor stars. When the explosion occurs in such winds, the transition between the ED and the ST phase is likely to take place within a few tens of years. The highest energies are reached at even earlier times, when, however, a small fraction of the mass of ejecta has been processed. As a result, the spectrum of accelerated particles shows a break in the slope, at an energy that is the maximum energy (EM) achieved at the beginning of the ST phase. Above this characteristic energy, the spectrum becomes steeper but remains a power law rather than developing an exponential cutoff. An exponential cut is eventually present at much higher energies but it does not have a phenomenological relevance. We show that for parameters typical of type II supernovae, EM for protons can easily reach values in the PeV range, confirming that type II SNRs are the best candidate sources for CRs at the knee. From the point of view of implications of this scenario on the measured particle spectra, we have tried to fit KASCADE-Grande, ARGO -YBJ and YAC1-Tibet Array data with our model but we could not find any combination of the parameters that could explain all data sets. Indeed the recent measurement of the proton and helium spectra in the knee region, with the ARGO-YBJ and YAC1-Tibet Array, has made the situation very confused. These measurements suggest that the knee in the light component is at ∼ 650 TeV, appreciably below the knee in the overall spectrum. On one hand this finding would resolve the problem of reaching very high energies in supernovae, but on the other it would open a critical issue in the transition region between Galactic and extragalactic CRs.
Shewanella putrefaciens Adhesion and Biofilm Formation on Food Processing Surfaces
Bagge, Dorthe; Hjelm, Mette; Johansen, Charlotte; Huber, Ingrid; Gram, Lone
2001-01-01
Laboratory model systems were developed for studying Shewanella putrefaciens adhesion and biofilm formation under batch and flow conditions. S. putrefaciens plays a major role in food spoilage and may cause microbially induced corrosion on steel surfaces. S. putrefaciens bacteria suspended in buffer adhered readily to stainless steel surfaces. Maximum numbers of adherent bacteria per square centimeter were reached in 8 h at 25°C and reflected the cell density in suspension. Numbers of adhering bacteria from a suspension containing 108 CFU/ml were much lower in a laminar flow system (modified Robbins device) (reaching 102 CFU/cm2) than in a batch system (reaching 107 CFU/cm2), and maximum numbers were reached after 24 h. When nutrients were supplied, S. putrefaciens grew in biofilms with layers of bacteria. The rate of biofilm formation and the thickness of the film were not dependent on the availability of carbohydrate (lactate or glucose) or on iron starvation. The number of S. putrefaciens bacteria on the surface was partly influenced by the presence of other bacteria (Pseudomonas fluorescens) which reduced the numbers of S. putrefaciens bacteria in the biofilm. Numbers of bacteria on the surface must be quantified to evaluate the influence of environmental factors on adhesion and biofilm formation. We used a combination of fluorescence microscopy (4′,6′-diamidino-2-phenylindole staining and in situ hybridization, for mixed-culture studies), ultrasonic removal of bacteria from surfaces, and indirect conductometry and found this combination sufficient to quantify bacteria on surfaces. PMID:11319118
Liu, Susu; Liu, Xianhua; Wang, Ying; Zhang, Pingping
2016-12-01
The goal of this work was to develop a method for the direct power generation using macroalgae Enteromorpha prolifera. The process conditions for the saccharification of macroalgae were optimized and a type of alkaline fuel cell contained no precious metal catalysts was developed. Under optimum conditions (170°C and 2% hydrochloric acid for 45min), dilute acid hydrolysis of the homogenized plants yielded 272.25g reducing sugar/kg dry algal biomass. The maximum power density reached 3.81W/m 2 under the condition of 3M KOH and 18.15g/L reducing sugar in hydrolysate, higher than any other reported algae-fed fuel cells. This study represents the first report on direct electricity generation from macroalgae using alkaline fuel cells, suggesting that there is great potential for the production of renewable energy using marine biomass. Copyright © 2016 Elsevier Ltd. All rights reserved.
Investigation of scene identification algorithms for radiation budget measurements
NASA Technical Reports Server (NTRS)
Diekmann, F. J.
1986-01-01
The computation of Earth radiation budget from satellite measurements requires the identification of the scene in order to select spectral factors and bidirectional models. A scene identification procedure is developed for AVHRR SW and LW data by using two radiative transfer models. These AVHRR GAC pixels are then attached to corresponding ERBE pixels and the results are sorted into scene identification probability matrices. These scene intercomparisons show that there generally is a higher tendency for underestimation of cloudiness over ocean at high cloud amounts, e.g., mostly cloudy instead of overcast, partly cloudy instead of mostly cloudy, for the ERBE relative to the AVHRR results. Reasons for this are explained. Preliminary estimates of the errors of exitances due to scene misidentification demonstrates the high dependency on the probability matrices. While the longwave error can generally be neglected the shortwave deviations have reached maximum values of more than 12% of the respective exitances.
Li, W.; Claassen, M.; Chang, Cui -Zu; ...
2016-09-07
The experimental realization of the quantum anomalous Hall (QAH) effect in magnetically-doped (Bi, Sb) 2Te 3 films stands out as a landmark of modern condensed matter physics. However, ultra-low temperatures down to few tens of mK are needed to reach the quantization of Hall resistance, which is two orders of magnitude lower than the ferromagnetic phase transition temperature of the films. Here, we systematically study the band structure of V-doped (Bi, Sb) 2Te 3 thin films by angle-resolved photoemission spectroscopy (ARPES) and show unambiguously that the bulk valence band (BVB) maximum lies higher in energy than the surface state Diracmore » point. Finally, our results demonstrate clear evidence that localization of BVB carriers plays an active role and can account for the temperature discrepancy.« less
Two-Dimensional Vanadium Carbide (MXene) as Positive Electrode for Sodium-Ion Capacitors.
Dall'Agnese, Yohan; Taberna, Pierre-Louis; Gogotsi, Yury; Simon, Patrice
2015-06-18
Ion capacitors store energy through intercalation of cations into an electrode at a faster rate than in batteries and within a larger potential window. These devices reach a higher energy density compared to electrochemical double layer capacitor. Li-ion capacitors are already produced commercially, but the development of Na-ion capacitors is hindered by lack of materials that would allow fast intercalation of Na-ions. Here we investigated the electrochemical behavior of 2D vanadium carbide, V2C, from the MXene family. We investigated the mechanism of Na intercalation by XRD and achieved capacitance of ∼100 F/g at 0.2 mV/s. We assembled a full cell with hard carbon as negative electrode, a known anode material for Na ion batteries, and achieved capacity of 50 mAh/g with a maximum cell voltage of 3.5 V.
Changes in apple liquid phase concentration throughout equilibrium in osmotic dehydration.
Barat, J M; Barrera, C; Frías, J M; Fito, P
2007-03-01
Previous results on apple tissue equilibration during osmotic dehydration showed that, at very long processing times, the solute concentrations of the fruit liquid phase and the osmotic solution were the same. In the present study, changes in apple liquid phase composition throughout equilibrium in osmotic dehydration were analyzed and modeled. Results showed that, by the time osmosed samples reached the maximum weight and volume loss, solute concentration of the fruit liquid phase was higher than that of the osmotic solution. The reported overconcentration could be explained in terms of the apple structure shrinkage that occurred during the osmotic dehydration with highly concentrated osmotic solutions due to the elastic response of the food structure to the loss of water and intake of solutes. The fruit liquid phase overconcentration rate was observed to depend on the concentration of the osmotic solution, the processing temperature, the sample size, and shape of the cellular tissue.
Zhu, Jingrun; Yang, Xiaoling; Zhu, Yihua; Wang, Yuanwei; Cai, Jin; Shen, Jianhua; Sun, Luyi; Li, Chunzhong
2017-09-07
Here we report the room-temperature, atmospheric synthesis of Mn-doped cesium lead halide (CsPbX 3 ) perovskite quantum dots (QDs). The synthesis is performed without any sort of protection, and the dual-color emission mechanism is revealed by density functional theory. The Mn concentration reaches a maximum atomic percentage of 37.73 at%, which is significantly higher in comparison to those achieved in earlier reports via high temperature hot injection method. The optical properties of as-prepared nanocrystals (NCs) remain consistent even after several months. Therefore, red-orange LEDs were fabricated by coating the composite of PS and as-prepared QDs onto ultraviolet LED chips. Additionally, the present approach may open up new methods for doping other ions in CsPbX 3 QDs under room temperature, the capability of which is essential for applications such as memristors and other devices.
High strain rate properties of off-axis composite laminates, part 2
NASA Technical Reports Server (NTRS)
Daniel, I. M.
1991-01-01
Unidirectional off-axis graphite/epoxy and graphite/S-glass/epoxy laminates were characterized in uniaxial tension at strain rates ranging from quasi-static to over 500 s(sup -1). Laminate ring specimens were loaded by internal pressure with the tensile stress at 22.5, 30, and 45 degrees relative to the fiber direction. Results were presented in the form of stress-strain curves to failure. Properties determined included moduli, Poisson's ratios, strength, and ultimate strain. In all three laminates of both materials the modulus and strength increase sharply with strain rate, reaching values roughly 100, 150, and 200 percent higher than corresponding static values for the 22.5(sub 8), 30(sub 8), and 45(sub 8) degree laminates, respectively. In the case of ultimate strain no definite trends could be established, but the maximum deviation from the average of any value for any strain rate was less than 18 percent.
Enhanced production of fructosyltransferase in Aspergillus oryzae by genome shuffling.
Wang, Shenghai; Duan, Mengjie; Liu, Yalan; Fan, Sen; Lin, Xiaoshan; Zhang, Yi
2017-03-01
To breed Aspergillus oryzae strains with high fructosyltransferase (FTase) activity using intraspecific protoplast fusion via genome-shuffling. A candidate library was developed using UV/LiCl of the conidia of A. oryzae SBB201. By screening for enzyme activity and cell biomass, two mutants (UV-11 and UV-76) were chosen for protoplast fusion and subsequent genome shuffling. After three rounds of genome recombination, a fusion mutant RIII-7 was obtained. Its FTase activity was 180 U g -1 , approximately double that of the original strain, and RIII-7 was genetically stable. In fermentation culture, FTase activity of the genome-shuffled strain reached a maximum of 353 U g -1 using substrate-feeding method, and this value was approximately 3.4-times higher than that of the original strain A. oryzae SBB201. Intraspecific protoplast fusion of A. oryzae significantly enhanced FTase activity and generated a potentially useful strain for industrial production.
Acoustic emission characterization of steel fibre reinforced concrete during bending
NASA Astrophysics Data System (ADS)
Aggelis, D. G.; Soulioti, D. V.; Sapouridis, N.; Barkoula, N. M.; Paipetis, A. S.; Matikas, T. E.
2010-04-01
The acoustic emission (AE) behaviour of steel fibre reinforced concrete is studied in this paper. The experiments were conducted in four-point bending with concurrent monitoring of AE signals. The sensors used, were of broadband response in order to capture a wide range of fracturing phenomena. The results indicate that AE parameters undergo significant changes much earlier than the final fracture of the specimens, even if the AE hit rate seems approximately constant. Specifically, the Ib-value which takes into account the amplitude distribution of the recent AE hits decreases when the load reaches about 60-70 % of its maximum value. Additionally, the average frequency of the signals decreases abruptly when a fracture incident occurs, indicating that matrix cracking events produce higher frequencies than fibre pull-out events. It is concluded that proper study of AE parameters enables the characterization of structural health of large structures in cases where remote monitoring is applied.