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Sample records for real time three-dimensional

  1. Real time three dimensional sensing system

    DOEpatents

    Gordon, S.J.

    1996-12-31

    The invention is a three dimensional sensing system which utilizes two flexibly located cameras for receiving and recording visual information with respect to a sensed object illuminated by a series of light planes. Each pixel of each image is converted to a digital word and the words are grouped into stripes, each stripe comprising contiguous pixels. One pixel of each stripe in one image is selected and an epi-polar line of that point is drawn in the other image. The three dimensional coordinate of each selected point is determined by determining the point on said epi-polar line which also lies on a stripe in the second image and which is closest to a known light plane. 7 figs.

  2. Real time three dimensional sensing system

    DOEpatents

    Gordon, Steven J.

    1996-01-01

    The invention is a three dimensional sensing system which utilizes two flexibly located cameras for receiving and recording visual information with respect to a sensed object illuminated by a series of light planes. Each pixel of each image is converted to a digital word and the words are grouped into stripes, each stripe comprising contiguous pixels. One pixel of each stripe in one image is selected and an epi-polar line of that point is drawn in the other image. The three dimensional coordinate of each selected point is determined by determining the point on said epi-polar line which also lies on a stripe in the second image and which is closest to a known light plane.

  3. Real-time construction of three-dimensional occupancy maps

    SciTech Connect

    Jones, J.P.

    1992-01-01

    This paper describes a preliminary sensory system for real-time sensor-based navigation in a three-dimensional, dynamic environment. Data from a laser range camera are processed on an iWarp parallel computer to create a 3D occupancy map. This map is rendered using raytracing. The construction and rendering consume less than 800 milliseconds.

  4. Real-time construction of three-dimensional occupancy maps

    SciTech Connect

    Jones, J.P.

    1992-12-01

    This paper describes a preliminary sensory system for real-time sensor-based navigation in a three-dimensional, dynamic environment. Data from a laser range camera are processed on an iWarp parallel computer to create a 3D occupancy map. This map is rendered using raytracing. The construction and rendering consume less than 800 milliseconds.

  5. Real-time, Three-dimensional Aquifer Imaging

    NASA Astrophysics Data System (ADS)

    Guzman, A.; Jones, J. W.; Mongrain, R. A.

    2009-12-01

    Commonly-employed subsurface investigation techniques such as drilling and soil sampling, aquifer testing, tracer testing, groundwater sampling and analytical test work yield valuable subsurface information, yet they provide little direct information about the migration pathways followed by contaminants. Meaningful site assessment and remediation work require an accurate assessment of these migration pathways. Since these pathways generally represent a small proportion of the subsurface, accurate characterization data are key to the design of effective remediation programs on a contaminated site. Methods capable of interrogating volumetric properties of the subsurface are necessary to define migration pathways followed by contaminants, develop an accurate conceptualization of the subsurface, and to support a better understanding of contaminant conditions. Of course, to be of practical use at ‘typical’ sites, the methods must be cost-effective and work in existing conventionally-completed monitoring wells. This paper presents the results of real-time geophysical measurements in the context of a tracer test that used de-ionized water and a fluorescent tracer. The purpose of these field activities was to conduct detailed characterization of the aquifer properties to support the design of a groundwater remediation program. The geophysical approach provided real-time, 3 D measurement and images of the evolving changes in the electric conductivity (resistivity) and oxidation-reduction potential (ORP) in the aquifer. The de-ionized water provided strong electrochemical changes and allowed both parameters to be rapidly and cost-effectively measured in-situ. Our approach provided continuous monitoring of these diagnostic parameters using readily-deployed down-hole electrode arrays to generate detailed profiles in multiple wells and cross-hole resistivity images of groundwater conditions, prior to, during and after the tracer injection. The geophysical data clearly

  6. The application of holography as a real-time three-dimensional motion picture camera

    NASA Technical Reports Server (NTRS)

    Kurtz, R. L.

    1973-01-01

    A historical introduction to holography is presented, as well as a basic description of sideband holography for stationary objects. A brief theoretical development of both time-dependent and time-independent holography is also provided, along with an analytical and intuitive discussion of a unique holographic arrangement which allows the resolution of front surface detail from an object moving at high speeds. As an application of such a system, a real-time three-dimensional motion picture camera system is discussed and the results of a recent demonstration of the world's first true three-dimensional motion picture are given.

  7. Real-time construction and rendering of three-dimensional occupancy maps

    SciTech Connect

    Jones, J.P.

    1993-03-01

    This paper describes a preliminary sensory system for real-time sensor-based navigation in a three-dimensional, dynamic environment. Data fro a laser range camera are processed on an iWarp parallel computer to create a 3D occupancy map. This map is rendered using raytracing. The construction and rendering consume less than 800 milliseconds.

  8. Real-time construction and rendering of three-dimensional occupancy maps

    SciTech Connect

    Jones, J.P.

    1993-01-01

    This paper describes a preliminary sensory system for real-time sensor-based navigation in a three-dimensional, dynamic environment. Data fro a laser range camera are processed on an iWarp parallel computer to create a 3D occupancy map. This map is rendered using raytracing. The construction and rendering consume less than 800 milliseconds.

  9. Large field of view real-time three-dimensional imaging for ports

    NASA Astrophysics Data System (ADS)

    Gao, Meijing; Wu, Weilong; Gu, Haihua; Bi, Weihong

    2011-06-01

    With the acceleration of globalization and regionalization of the world economy, port is playing an increasingly important role for that it is an international transportation hub port interface and the support of the international trade platform. How to effectively reduce labor costs, improve the working environment, stable productivity, reduce the production cuts caused by human intervention and improve the management of real-time monitoring of all the major ports has become a common issue faced. In order to achieve the automatically stacking and reclaiming process of Stacker-Reclaimer in the bulk material yard, the source of its control is expected to identify the stockpile in the bulk yard, including length, width, height, the starting address, destination address, as well as Three-dimensional shape of the stockpile, since in the operation process, stockpile changes the shape dynamically. As a result, the real-time three-dimensional shape and coordinate of piles should be achieved. Based on the existing Stacker-Reclaimer in Qinhuangdao Port coal, we study the large field of view real-time three-dimensional laser scanning imaging theory and technology. The overall system design to achieving the three-dimensional laser scanning image is presented. The working principle of the three-dimensional laser scanning imaging system is analysised. Moreover, the parameter designation, the technical parameters and the composition of the whole system are all given. The research of the thesis is also used for other large-scale three-dimensional modeling of piles and the volume computing. In a world, the method has wide application prospect.

  10. Real-time three dimensional sonographic features of an early third trimester fetus with achondrogenesis.

    PubMed

    Wataganara, Tuangsit; Sutanthavibool, Anuwat; Limwongse, Chanin

    2006-10-01

    Generalized shortening of fetal long bones detected from prenatal sonographic examination usually raise a tentative diagnosis of skeletal dysplasia. Information obtained from grey-scale scan is frequently not sufficient to provide a definite diagnosis, and the images are not readily comprehensible for the parents-to-be. Lately, three-dimensional sonography has become increasing available in obstetric practice. The authors report here a rare case of fetal achondrogenesis, which is a lethal form of skeletal dysplasia, in a 30-week-old fetus using real-time three-dimensional ultrasound. The prenatal findings of fetal achondrogenesis from this technique were thoroughly described, along with postnatal radiography and autopsy results. Sonographic features from this imaging technique allow for an accurate diagnosis and better understanding of the parents. This facilitates the genetic counseling process, as well as the parental options for further care. PMID:17128855

  11. Incorporation of thermal shadows into real-time infrared three-dimensional image generation

    NASA Astrophysics Data System (ADS)

    Klein, Andreas; Nischwitz, Alfred; Schätz, Peter; Obermeier, Paul

    2014-05-01

    In the infrared spectrum, two contributions to shadows exist: one part is reflective shadows resulting from occlusion of instantly reflected infrared rays, and the other part is thermal (IR) shadows occurring through occlusion of irradiance in the past. The realization of thermal shadows requires a thermal balance calculation in four-dimensions (three-dimensional geometry in one-dimensional time), which is computationally expensive, and therefore mostly used for nonreal-time simulations. We present an approximation of thermal shadows resulting from the occlusion of direct rays from IR emitters. Our approach uses programmable graphics cards to achieve real-time frame rates in scenes with dynamic geometry.

  12. Real-time, interactive animation of deformable two- and three-dimensional objects

    DOEpatents

    Desbrun, Mathieu; Schroeder, Peter; Meyer, Mark; Barr, Alan H.

    2003-06-03

    A method of updating in real-time the locations and velocities of mass points of a two- or three-dimensional object represented by a mass-spring system. A modified implicit Euler integration scheme is employed to determine the updated locations and velocities. In an optional post-integration step, the updated locations are corrected to preserve angular momentum. A processor readable medium and a network server each tangibly embodying the method are also provided. A system comprising a processor in combination with the medium, and a system comprising the server in combination with a client for accessing the server over a computer network, are also provided.

  13. Real-time three-dimensional surface measurement by color encoded light projection

    SciTech Connect

    Chen, S. Y.; Li, Y. F.; Guan, Q.; Xiao, G.

    2006-09-11

    Existing noncontact methods for surface measurement suffer from the disadvantages of poor reliability, low scanning speed, or high cost. The authors present a method for real-time three-dimensional data acquisition by a color-coded vision sensor composed of common components. The authors use a digital projector controlled by computer to generate desired color light patterns. The unique indexing of the light codes is a key problem and is solved in this study so that surface perception can be performed with only local pattern analysis of the neighbor color codes in a single image. Experimental examples and performance analysis are provided.

  14. Real-time three-dimensional fingerprint acquisition via a new photometric stereo means

    NASA Astrophysics Data System (ADS)

    Xie, Wuyuan; Song, Zhan; Chung, Ronald

    2013-10-01

    A real-time means for three-dimensional (3-D) fingerprint acquisition is presented. The system is configured with only one camera and some white light-emitting diode lamps. The reconstruction is performed based on the principle of photometric stereo. In the algorithm, a two-layer Hanrahan-Krueger model is proposed to represent the finger surface reflectance property instead of the traditional Lambert model. By the proposed lighting direction calibration and the nonuniform lighting correction methods, surface normal at each image point can be accurately estimated by solving a nonlinear optimization problem. Finally, a linear normal transformation is implemented for the enhancement of 3-D models. The experiments are implemented with real finger and palm prints, and the results are also compared with traditional means to show its feasibility and improvement in the reconstruction accuracy.

  15. Three-dimensional fuzzy-directional processing to impulse video color denoising in real time environment

    NASA Astrophysics Data System (ADS)

    Rosales-Silva, Alberto J.; Ponomaryov, Volodymyr; Gallegos-Funes, Francisco

    2009-05-01

    It is presented a robust three dimensional scheme using fuzzy and directional techniques in denoising video color images contaminated by impulsive random noise. This scheme estimates a noise and movement level in local area, detecting edges and fine details in an image video sequence. The proposed approach cares the chromaticity properties in multidimensional and multichannel images. The algorithm was specially designed to reduce computational charge, and its performance is quantified using objective criteria, such as Pick Signal Noise Relation, Mean Absolute Error and Normalized Color Difference, as well visual subjective views. Novel filter shows superiority rendering against other well known algorithms found in the literature. Real-time analysis is realized on Digital Signal Processor to outperform processing capability. The DSP was designed by Texas Instruments for multichannel processing in the multitask process, and permits to improve the performance of several tasks, and at the same time enhancing processing time and reducing computational charge in such a dedicated hardware.

  16. Three-dimensional dose evaluation system using real-time wind field information for nuclear accidents in Taiwan

    NASA Astrophysics Data System (ADS)

    Wu, Jay; Lu, Chung-Hsin; Chang, Shu-Jun; Yang, Yung-Muh; Chang, Bor-Jing; Teng, Jen-Hsin

    2006-09-01

    In Taiwan, the three operating nuclear power plants are all built along the coast over complex terrain. Dose estimates after a nuclear accident with releases of radioactive materials, therefore, cannot be accurately calculated using simple dispersion models. We developed a three-dimensional dose evaluation system, which incorporates real-time prognostic wind field information with three-dimensional numerical models to predict dose results. The proposed system consists of three models: a three-dimensional mesoscale atmospheric model (HOTMAC), a three-dimensional transport and diffusion model (RAPTAD), and a dose calculation model (DOSE). The whole-body dose and thyroid dose as well as dose rates can be rapidly estimated and displayed on the three-dimensional terrain model constructed by satellite images. The developed three-dimensional dose evaluation system could accurately forecast the dose results and has been used in the annual nuclear emergency response exercise to provide suggestions for protective measures.

  17. Real-time and three-dimensional MRI for diagnosis of pharyngoceles.

    PubMed

    Traser, Louisa; Spahn, Claudia; Richter, Bernhard; Baumann, Tobias; Schumacher, Martin; Echternach, Matthias

    2014-07-01

    In the evaluation of patients with local pathologic dilatation inside the upper airway a pressure-related testing seems important for understanding its pathophysiology and for developing a concept of intra-individually adjusted therapy. Commonly used diagnostic techniques like endoscopy or medical imaging including ultrasound, barium swallow or computer-assisted tomography (CT) have shown limitations either in evaluating a dynamic process or assessing the entirety of cervical structures. This article presents a case report of a professional trumpet player with bilateral pharyngoceles, introducing real-time and three-dimensional (3D) MRI as a helpful tool in the diagnosis of pressure dependent pathologies in the upper airway. With the use of MRI the complete sub- and supraglottic airway can be viewed simultaneously, avoiding the distortion which can occur with endoscopy. Thus, it was possible to evaluate the pharyngoceles pressure-related pathophysiology, from which a successful therapy could be conceived which included modifying the musician's blowing technique. PMID:24395345

  18. Real-time three-dimensional intracardiac echocardiography: an early single-center experience.

    PubMed

    Maini, Brijeshwar

    2015-01-01

    As interventional procedures in structural heart diseases are coming of age, there is a significant lag in the periinterventional imaging development for these procedures to become safe, expedient, accurate, and well tolerated by this patient population. Currently, transesophageal echocardiography (TEE), including real-time three-dimensional (RT-3D), has been used for monitoring and guidance for these procedures. Accurate identification of the pathology, its anatomy, and its relationship with the adjoining structures along with spatial resolution is of paramount importance for wire and catheter placement, device deployment, evaluation of the results, and any potential complications. Two-dimensional intracardiac echocardiography (ICE) has been used extensively for a variety of interventional procedures that undergo conscious sedation of monitored anesthesia. RT-3D ICE has recently become available; we describe our initial experience with this new imaging technology. PMID:25589706

  19. Acoustic Performance of a Real-Time Three-Dimensional Sound-Reproduction System

    NASA Technical Reports Server (NTRS)

    Faller, Kenneth J., II; Rizzi, Stephen A.; Aumann, Aric R.

    2013-01-01

    The Exterior Effects Room (EER) is a 39-seat auditorium at the NASA Langley Research Center and was built to support psychoacoustic studies of aircraft community noise. The EER has a real-time simulation environment which includes a three-dimensional sound-reproduction system. This system requires real-time application of equalization filters to compensate for spectral coloration of the sound reproduction due to installation and room effects. This paper describes the efforts taken to develop the equalization filters for use in the real-time sound-reproduction system and the subsequent analysis of the system s acoustic performance. The acoustic performance of the compensated and uncompensated sound-reproduction system is assessed for its crossover performance, its performance under stationary and dynamic conditions, the maximum spatialized sound pressure level it can produce from a single virtual source, and for the spatial uniformity of a generated sound field. Additionally, application examples are given to illustrate the compensated sound-reproduction system performance using recorded aircraft flyovers

  20. Real-time three-dimensional Fourier-domain optical coherence tomography video image guided microsurgeries

    NASA Astrophysics Data System (ADS)

    Kang, Jin U.; Huang, Yong; Zhang, Kang; Ibrahim, Zuhaib; Cha, Jaepyeong; Lee, W. P. Andrew; Brandacher, Gerald; Gehlbach, Peter L.

    2012-08-01

    The authors describe the development of an ultrafast three-dimensional (3D) optical coherence tomography (OCT) imaging system that provides real-time intraoperative video images of the surgical site to assist surgeons during microsurgical procedures. This system is based on a full-range complex conjugate free Fourier-domain OCT (FD-OCT). The system was built in a CPU-GPU heterogeneous computing architecture capable of video OCT image processing. The system displays at a maximum speed of 10 volume/s for an image volume size of 160×80×1024 (X×Y×Z) pixels. We have used this system to visualize and guide two prototypical microsurgical maneuvers: microvascular anastomosis of the rat femoral artery and ultramicrovascular isolation of the retinal arterioles of the bovine retina. Our preliminary experiments using 3D-OCT-guided microvascular anastomosis showed optimal visualization of the rat femoral artery (diameter<0.8 mm), instruments, and suture material. Real-time intraoperative guidance helped facilitate precise suture placement due to optimized views of the vessel wall during anastomosis. Using the bovine retina as a model system, we have performed "ultra microvascular" feasibility studies by guiding handheld surgical micro-instruments to isolate retinal arterioles (diameter˜0.1 mm). Isolation of the microvessels was confirmed by successfully passing a suture beneath the vessel in the 3D imaging environment.

  1. Real-time three-dimensional Fourier-domain optical coherence tomography video image guided microsurgeries

    PubMed Central

    Huang, Yong; Zhang, Kang; Ibrahim, Zuhaib; Cha, Jaepyeong; Lee, W. P. Andrew; Brandacher, Gerald; Gehlbach, Peter L.

    2012-01-01

    Abstract. The authors describe the development of an ultrafast three-dimensional (3D) optical coherence tomography (OCT) imaging system that provides real-time intraoperative video images of the surgical site to assist surgeons during microsurgical procedures. This system is based on a full-range complex conjugate free Fourier-domain OCT (FD-OCT). The system was built in a CPU-GPU heterogeneous computing architecture capable of video OCT image processing. The system displays at a maximum speed of 10  volume/s for an image volume size of 160×80×1024 (X×Y×Z) pixels. We have used this system to visualize and guide two prototypical microsurgical maneuvers: microvascular anastomosis of the rat femoral artery and ultramicrovascular isolation of the retinal arterioles of the bovine retina. Our preliminary experiments using 3D-OCT-guided microvascular anastomosis showed optimal visualization of the rat femoral artery (diameter<0.8  mm), instruments, and suture material. Real-time intraoperative guidance helped facilitate precise suture placement due to optimized views of the vessel wall during anastomosis. Using the bovine retina as a model system, we have performed “ultra microvascular” feasibility studies by guiding handheld surgical micro-instruments to isolate retinal arterioles (diameter∼0.1  mm). Isolation of the microvessels was confirmed by successfully passing a suture beneath the vessel in the 3D imaging environment. PMID:23224164

  2. Three-dimensional localization of low activity gamma-ray sources in real-time scenarios

    NASA Astrophysics Data System (ADS)

    Sharma, Manish K.; Alajo, Ayodeji B.; Lee, Hyoung K.

    2016-03-01

    Radioactive source localization plays an important role in tracking radiation threats in homeland security tasks. Its real-time application requires computationally efficient and reasonably accurate algorithms even with limited data to support detection with minimum uncertainty. This paper describes a statistic-based grid-refinement method for backtracing the position of a gamma-ray source in a three-dimensional domain in real-time. The developed algorithm used measurements from various known detector positions to localize the source. This algorithm is based on an inverse-square relationship between source intensity at a detector and the distance from the source to the detector. The domain discretization was developed and implemented in MATLAB. The algorithm was tested and verified from simulation results of an ideal case of a point source in non-attenuating medium. Subsequently, an experimental validation of the algorithm was performed to determine the suitability of deploying this scheme in real-time scenarios. Using the measurements from five known detector positions and for a measurement time of 3 min, the source position was estimated with an accuracy of approximately 53 cm. The accuracy improved and stabilized to approximately 25 cm for higher measurement times. It was concluded that the error in source localization was primarily due to detection uncertainties. In verification and experimental validation of the algorithm, the distance between 137Cs source and any detector position was between 0.84 m and 1.77 m. The results were also compared with the least squares method. Since the discretization algorithm was validated with a weak source, it is expected that it can localize the source of higher activity in real-time. It is believed that for the same physical placement of source and detectors, a source of approximate activity 0.61-0.92 mCi can be localized in real-time with 1 s of measurement time and same accuracy. The accuracy and computational efficiency

  3. Full high-definition real-time depth estimation for three-dimensional video system

    NASA Astrophysics Data System (ADS)

    Li, Hejian; An, Ping; Zhang, Zhaoyang

    2014-09-01

    Three-dimensional (3-D) video brings people strong visual perspective experience, but also introduces large data and complexity processing problems. The depth estimation algorithm is especially complex and it is an obstacle for real-time system implementation. Meanwhile, high-resolution depth maps are necessary to provide a good image quality on autostereoscopic displays which deliver stereo content without the need for 3-D glasses. This paper presents a hardware implementation of a full high-definition (HD) depth estimation system that is capable of processing full HD resolution images with a maximum processing speed of 125 fps and a disparity search range of 240 pixels. The proposed field-programmable gate array (FPGA)-based architecture implements a fusion strategy matching algorithm for efficiency design. The system performs with high efficiency and stability by using a full pipeline design, multiresolution processing, synchronizers which avoid clock domain crossing problems, efficient memory management, etc. The implementation can be included in the video systems for live 3-D television applications and can be used as an independent hardware module in low-power integrated applications.

  4. Toward real-time three-dimensional mapping of surficial aquifers using a hybrid modeling approach

    NASA Astrophysics Data System (ADS)

    Friedel, Michael J.; Esfahani, Akbar; Iwashita, Fabio

    2016-02-01

    A hybrid modeling approach is proposed for near real-time three-dimensional (3D) mapping of surficial aquifers. First, airborne frequency-domain electromagnetic (FDEM) measurements are numerically inverted to obtain subsurface resistivities. Second, a machine-learning (ML) algorithm is trained using the FDEM measurements and inverted resistivity profiles, and borehole geophysical and hydrogeologic data. Third, the trained ML algorithm is used together with independent FDEM measurements to map the spatial distribution of the aquifer system. Efficacy of the hybrid approach is demonstrated for mapping a heterogeneous surficial aquifer and confining unit in northwestern Nebraska, USA. For this case, independent performance testing reveals that aquifer mapping is unbiased with a strong correlation (0.94) among numerically inverted and ML-estimated binary (clay-silt or sand-gravel) layer resistivities (5-20 ohm-m or 21-5,000 ohm-m), and an intermediate correlation (0.74) for heterogeneous (clay, silt, sand, gravel) layer resistivities (5-5,000 ohm-m). Reduced correlation for the heterogeneous model is attributed to over-estimating the under-sampled high-resistivity gravels (about 0.5 % of the training data), and when removed the correlation increases (0.87). Independent analysis of the numerically inverted and ML-estimated resistivities finds that the hybrid procedure preserves both univariate and spatial statistics for each layer. Following training, the algorithms can map 3D surficial aquifers as fast as leveled FDEM measurements are presented to the ML network.

  5. Real-time monitoring of cisplatin cytotoxicity on three-dimensional spheroid tumor cells

    PubMed Central

    Baek, NamHuk; Seo, Ok Won; Lee, Jaehwa; Hulme, John; An, Seong Soo A

    2016-01-01

    Three-dimensional (3D) cell cultivation is a powerful technique for monitoring and understanding diverse cellular mechanisms in developmental cancer and neuronal biology, tissue engineering, and drug development. 3D systems could relate better to in vivo models than two-dimensional (2D) cultures. Several factors, such as cell type, survival rate, proliferation rate, and gene and protein expression patterns, determine whether a particular cell line can be adapted to a 3D system. The 3D system may overcome some of the limitations of 2D cultures in terms of cell–cell communication and cell networks, which are essential for understanding differentiation, structural organization, shape, and extended connections with other cells or organs. Here, the effect of the anticancer drug cisplatin, also known as cis-diamminedichloroplatinum (II) or CDDP, on adenosine triphosphate (ATP) generation was investigated using 3D spheroid-forming cells and real-time monitoring for 7 days. First, 12 cell lines were screened for their ability to form 3D spheroids: prostate (DU145), testis (F9), embryonic fibroblast (NIH-3T3), muscle (C2C12), embryonic kidney (293T), neuroblastoma (SH-SY5Y), adenocarcinomic alveolar basal epithelial cell (A549), cervical cancer (HeLa), HeLa contaminant (HEp2), pituitary epithelial-like cell (GH3), embryonic cell (PA317), and osteosarcoma (U-2OS) cells. Of these, eight cell lines were selected: NIH-3T3, C2C12, 293T, SH-SY5Y, A549, HeLa, PA317, and U-2OS; and five underwent real-time monitoring of CDDP cytotoxicity: HeLa, A549, 293T, SH-SY5Y, and U-2OS. ATP generation was blocked 1 day after addition of 50 μM CDDP, but cytotoxicity in HeLa, A549, SH-SY5Y, and U-2OS cells could be visualized only 4 days after treatment. In 293T cells, CDDP failed to kill entirely the culture and ATP generation was only partially blocked after 1 day. This suggests potential CDDP resistance of 293T cells or metabolic clearance of the drug. Real-time monitoring and ATP

  6. Real-time monitoring of cisplatin cytotoxicity on three-dimensional spheroid tumor cells.

    PubMed

    Baek, NamHuk; Seo, Ok Won; Lee, Jaehwa; Hulme, John; An, Seong Soo A

    2016-01-01

    Three-dimensional (3D) cell cultivation is a powerful technique for monitoring and understanding diverse cellular mechanisms in developmental cancer and neuronal biology, tissue engineering, and drug development. 3D systems could relate better to in vivo models than two-dimensional (2D) cultures. Several factors, such as cell type, survival rate, proliferation rate, and gene and protein expression patterns, determine whether a particular cell line can be adapted to a 3D system. The 3D system may overcome some of the limitations of 2D cultures in terms of cell-cell communication and cell networks, which are essential for understanding differentiation, structural organization, shape, and extended connections with other cells or organs. Here, the effect of the anticancer drug cisplatin, also known as cis-diamminedichloroplatinum (II) or CDDP, on adenosine triphosphate (ATP) generation was investigated using 3D spheroid-forming cells and real-time monitoring for 7 days. First, 12 cell lines were screened for their ability to form 3D spheroids: prostate (DU145), testis (F9), embryonic fibroblast (NIH-3T3), muscle (C2C12), embryonic kidney (293T), neuroblastoma (SH-SY5Y), adenocarcinomic alveolar basal epithelial cell (A549), cervical cancer (HeLa), HeLa contaminant (HEp2), pituitary epithelial-like cell (GH3), embryonic cell (PA317), and osteosarcoma (U-2OS) cells. Of these, eight cell lines were selected: NIH-3T3, C2C12, 293T, SH-SY5Y, A549, HeLa, PA317, and U-2OS; and five underwent real-time monitoring of CDDP cytotoxicity: HeLa, A549, 293T, SH-SY5Y, and U-2OS. ATP generation was blocked 1 day after addition of 50 μM CDDP, but cytotoxicity in HeLa, A549, SH-SY5Y, and U-2OS cells could be visualized only 4 days after treatment. In 293T cells, CDDP failed to kill entirely the culture and ATP generation was only partially blocked after 1 day. This suggests potential CDDP resistance of 293T cells or metabolic clearance of the drug. Real-time monitoring and ATP

  7. Three-dimensional liver motion tracking using real-time two-dimensional MRI

    SciTech Connect

    Brix, Lau; Ringgaard, Steffen; Sørensen, Thomas Sangild; Poulsen, Per Rugaard

    2014-04-15

    Purpose: Combined magnetic resonance imaging (MRI) systems and linear accelerators for radiotherapy (MR-Linacs) are currently under development. MRI is noninvasive and nonionizing and can produce images with high soft tissue contrast. However, new tracking methods are required to obtain fast real-time spatial target localization. This study develops and evaluates a method for tracking three-dimensional (3D) respiratory liver motion in two-dimensional (2D) real-time MRI image series with high temporal and spatial resolution. Methods: The proposed method for 3D tracking in 2D real-time MRI series has three steps: (1) Recording of a 3D MRI scan and selection of a blood vessel (or tumor) structure to be tracked in subsequent 2D MRI series. (2) Generation of a library of 2D image templates oriented parallel to the 2D MRI image series by reslicing and resampling the 3D MRI scan. (3) 3D tracking of the selected structure in each real-time 2D image by finding the template and template position that yield the highest normalized cross correlation coefficient with the image. Since the tracked structure has a known 3D position relative to each template, the selection and 2D localization of a specific template translates into quantification of both the through-plane and in-plane position of the structure. As a proof of principle, 3D tracking of liver blood vessel structures was performed in five healthy volunteers in two 5.4 Hz axial, sagittal, and coronal real-time 2D MRI series of 30 s duration. In each 2D MRI series, the 3D localization was carried out twice, using nonoverlapping template libraries, which resulted in a total of 12 estimated 3D trajectories per volunteer. Validation tests carried out to support the tracking algorithm included quantification of the breathing induced 3D liver motion and liver motion directionality for the volunteers, and comparison of 2D MRI estimated positions of a structure in a watermelon with the actual positions. Results: Axial, sagittal

  8. Multi-camera real-time three-dimensional tracking of multiple flying animals.

    PubMed

    Straw, Andrew D; Branson, Kristin; Neumann, Titus R; Dickinson, Michael H

    2011-03-01

    Automated tracking of animal movement allows analyses that would not otherwise be possible by providing great quantities of data. The additional capability of tracking in real time--with minimal latency--opens up the experimental possibility of manipulating sensory feedback, thus allowing detailed explorations of the neural basis for control of behaviour. Here, we describe a system capable of tracking the three-dimensional position and body orientation of animals such as flies and birds. The system operates with less than 40 ms latency and can track multiple animals simultaneously. To achieve these results, a multi-target tracking algorithm was developed based on the extended Kalman filter and the nearest neighbour standard filter data association algorithm. In one implementation, an 11-camera system is capable of tracking three flies simultaneously at 60 frames per second using a gigabit network of nine standard Intel Pentium 4 and Core 2 Duo computers. This manuscript presents the rationale and details of the algorithms employed and shows three implementations of the system. An experiment was performed using the tracking system to measure the effect of visual contrast on the flight speed of Drosophila melanogaster. At low contrasts, speed is more variable and faster on average than at high contrasts. Thus, the system is already a useful tool to study the neurobiology and behaviour of freely flying animals. If combined with other techniques, such as 'virtual reality'-type computer graphics or genetic manipulation, the tracking system would offer a powerful new way to investigate the biology of flying animals.

  9. Quasi-real time inversion method of three-dimensional epicenter coordinate, trigger time, and magnitude based on CORS

    NASA Astrophysics Data System (ADS)

    Xiao, Dongsheng; Chang, Ming; Su, Yong; Hu, Qijun; Yu, Bing

    2016-09-01

    This study explores the quasi-real time inversion principle and precision estimation of three-dimensional coordinates of the epicenter, trigger time and magnitude of earthquakes with the aim to improve traditional methods, which are flawed due to missing information or distortion in the seismograph records. The epicenter, trigger time and magnitude from the Lushan earthquake are inverted and analyzed based on high-frequency GNSS data. The inversion results achieved a high precision, which are consistent with the data published by the China Earthquake Administration. Moreover, it has been proven that the inversion method has good theoretical value and excellent application prospects.

  10. Three-dimensional reconstruction of icosahedral particles from single micrographs in real time at the microscope

    PubMed Central

    Cardone, Giovanni; Yan, Xiaodong; Sinkovits, Robert S.; Tang, Jinghua; Baker, Timothy S.

    2013-01-01

    Single particle analysis is a valuable tool in cryo-electron microscopy for determining the structure of biological complexes. However, the conformational state and the preparation of the sample are factors that play a critical role in the ultimate attainable resolution. In some cases extensive analysis at the microscope of a sample under different conditions is required to derive the optimal acquisition conditions. Currently this analysis is limited to raw micrographs, thus conveying only limited information on the structure of the complex. We are developing a computing system that generates a three-dimensional reconstruction from a single micrograph acquired under cryogenic and low dose conditions, and containing particles with icosahedral symmetry. The system provides the microscopist with immediate structural information from a sample, while it is in the microscope and during the preliminary acquisition stage. The system is designed to run without user intervention on a multi-processor computing resource and integrates all the processing steps required for the analysis. Tests performed on experimental data sets show that the probability of obtaining a reliable reconstruction from one micrograph is primarily determined by the quality of the sample, with success rates close to 100% when sample conditions are optimal, and decreasing to about 60% when conditions are sub-optimal. The time required to generate a reconstruction depends significantly on the diameter of the particles, and in most instances takes about one minute. The proposed approach can provide valuable three-dimensional information, albeit at low resolution, on conformational states, epitope binding, and stoichiometry of icosahedral multi-protein complexes. PMID:23891839

  11. Multi-camera real-time three-dimensional tracking of multiple flying animals

    PubMed Central

    Straw, Andrew D.; Branson, Kristin; Neumann, Titus R.; Dickinson, Michael H.

    2011-01-01

    Automated tracking of animal movement allows analyses that would not otherwise be possible by providing great quantities of data. The additional capability of tracking in real time—with minimal latency—opens up the experimental possibility of manipulating sensory feedback, thus allowing detailed explorations of the neural basis for control of behaviour. Here, we describe a system capable of tracking the three-dimensional position and body orientation of animals such as flies and birds. The system operates with less than 40 ms latency and can track multiple animals simultaneously. To achieve these results, a multi-target tracking algorithm was developed based on the extended Kalman filter and the nearest neighbour standard filter data association algorithm. In one implementation, an 11-camera system is capable of tracking three flies simultaneously at 60 frames per second using a gigabit network of nine standard Intel Pentium 4 and Core 2 Duo computers. This manuscript presents the rationale and details of the algorithms employed and shows three implementations of the system. An experiment was performed using the tracking system to measure the effect of visual contrast on the flight speed of Drosophila melanogaster. At low contrasts, speed is more variable and faster on average than at high contrasts. Thus, the system is already a useful tool to study the neurobiology and behaviour of freely flying animals. If combined with other techniques, such as ‘virtual reality’-type computer graphics or genetic manipulation, the tracking system would offer a powerful new way to investigate the biology of flying animals. PMID:20630879

  12. Real-Time Simulation of Three-Dimensional Shoulder Girdle and Arm Dynamics

    PubMed Central

    Chadwick, Edward K.; Blana, Dimitra; Kirsch, Robert F.; van den Bogert, Antonie J.

    2014-01-01

    Electrical stimulation is a promising technology for the restoration of arm function in paralysed individuals. Control of the paralysed arm under electrical stimulation, however, is a challenging problem that requires advanced controllers and command interfaces for the user. A real-time model describing the complex dynamics of the arm would allow user-in-the-loop type experiments where the command interface and controller could be assessed. Real-time models of the arm previously described have not included the ability to model the independently controlled scapula and clavicle, limiting their utility for clinical applications of this nature. The goal of this study therefore was to evaluate the performance and mechanical behaviour of a real-time, dynamic model of the arm and shoulder girdle. The model comprises seven segments linked by eleven degrees of freedom and actuated by 138 muscle elements. Polynomials were generated to describe the muscle lines of action to reduce computation time, and an implicit, first-order Rosenbrock formulation of the equations of motion was used to increase simulation step-size. The model simulated flexion of the arm faster than real time, simulation time being 92% of actual movement time on standard desktop hardware. Modelled maximum isometric torque values agreed well with values from the literature, showing that the model simulates the moment-generating behaviour of a real human arm. The speed of the model enables experiments where the user controls the virtual arm and receives visual feedback in real time. The ability to optimise potential solutions in simulation greatly reduces the burden on the user during development. PMID:24956613

  13. Real-time simulation of three-dimensional shoulder girdle and arm dynamics.

    PubMed

    Chadwick, Edward K; Blana, Dimitra; Kirsch, Robert F; van den Bogert, Antonie J

    2014-07-01

    Electrical stimulation is a promising technology for the restoration of arm function in paralyzed individuals. Control of the paralyzed arm under electrical stimulation, however, is a challenging problem that requires advanced controllers and command interfaces for the user. A real-time model describing the complex dynamics of the arm would allow user-in-the-loop type experiments where the command interface and controller could be assessed. Real-time models of the arm previously described have not included the ability to model the independently controlled scapula and clavicle, limiting their utility for clinical applications of this nature. The goal of this study therefore was to evaluate the performance and mechanical behavior of a real-time, dynamic model of the arm and shoulder girdle. The model comprises seven segments linked by eleven degrees of freedom and actuated by 138 muscle elements. Polynomials were generated to describe the muscle lines of action to reduce computation time, and an implicit, first-order Rosenbrock formulation of the equations of motion was used to increase simulation step-size. The model simulated flexion of the arm faster than real time, simulation time being 92% of actual movement time on standard desktop hardware. Modeled maximum isometric torque values agreed well with values from the literature, showing that the model simulates the moment-generating behavior of a real human arm. The speed of the model enables experiments where the user controls the virtual arm and receives visual feedback in real time. The ability to optimize potential solutions in simulation greatly reduces the burden on the user during development. PMID:24956613

  14. Gradient-index lens-array method based on real-time integral photography for three-dimensional images

    NASA Astrophysics Data System (ADS)

    Arai, Jun; Okano, Fumio; Hoshino, Haruo; Yuyama, Ichiro

    1998-04-01

    Because a three-dimensional (3-D) autostereoscopic image can be seen from a desired viewpoint without the aid of special viewing glasses, integral photography (IP) is an ideal way to create 3-D autostereoscopic images. We have already proposed a real-time IP method that offers 3-D autostereoscopic images of moving objects in real time by use of a microlens array and a high-definition television camera. But there are two problems yet to be resolved: One is pseudoscopic images that show a reversed depth representation. The other is interference between the element images that constitute a 3-D autostereoscopic image. We describe a new gradient-index lense-array method based on real-time IP to overcome these two problems. Experimental results indicating the advantages of this method are shown. These results suggest the possibility of using a gradient-index lens array for real-time IP.

  15. Real-time application of advanced three-dimensional graphic techniques for research aircraft simulation

    NASA Technical Reports Server (NTRS)

    Davis, Steven B.

    1990-01-01

    Visual aids are valuable assets to engineers for design, demonstration, and evaluation. Discussed here are a variety of advanced three-dimensional graphic techniques used to enhance the displays of test aircraft dynamics. The new software's capabilities are examined and possible future uses are considered.

  16. Towards a Three-Dimensional Near-Real Time Cloud Product for Aviation Safety and Weather Diagnoses

    NASA Technical Reports Server (NTRS)

    Minnis, Patrick; Nguyen, Louis; Palikonda, Rabindra; Spangeberg, Douglas; Nordeen, Michele L.; Yi, Yu-Hong; Ayers, J. Kirk

    2004-01-01

    Satellite data have long been used for determining the extent of cloud cover and for estimating the properties at the cloud tops. The derived properties can also be used to estimate aircraft icing potential to improve the safety of air traffic in the region. Currently, cloud properties and icing potential are derived in near-real time over the United States of America (USA) from the Geostationary Operational Environmental Satellite GOES) imagers at 75 W and 135 W. Traditionally, the results have been given in two dimensions because of the lack of knowledge about the vertical extent of clouds and the occurrence of overlapping clouds. Aircraft fly in a three-dimensional space and require vertical as well as horizontal information about clouds, their intensity, and their potential for icing. To improve the vertical component of the derived cloud and icing parameters, this paper explores various methods and datasets for filling in the three-dimensional space over the USA with cloud water.

  17. Determination of left ventricular volume, ejection fraction, and myocardial mass by real-time three-dimensional echocardiography

    NASA Technical Reports Server (NTRS)

    Qin, J. X.; Shiota, T.; Thomas, J. D.

    2000-01-01

    Reconstructed three-dimensional (3-D) echocardiography is an accurate and reproducible method of assessing left ventricular (LV) functions. However, it has limitations for clinical study due to the requirement of complex computer and echocardiographic analysis systems, electrocardiographic/respiratory gating, and prolonged imaging times. Real-time 3-D echocardiography has a major advantage of conveniently visualizing the entire cardiac anatomy in three dimensions and of potentially accurately quantifying LV volumes, ejection fractions, and myocardial mass in patients even in the presence of an LV aneurysm. Although the image quality of the current real-time 3-D echocardiographic methods is not optimal, its widespread clinical application is possible because of the convenient and fast image acquisition. We review real-time 3-D echocardiographic image acquisition and quantitative analysis for the evaluation of LV function and LV mass.

  18. Real-time optical gating for three-dimensional beating heart imaging

    NASA Astrophysics Data System (ADS)

    Taylor, Jonathan M.; Saunter, Christopher D.; Love, Gordon D.; Girkin, John M.; Henderson, Deborah J.; Chaudhry, Bill

    2011-11-01

    We demonstrate real-time microscope image gating to an arbitrary position in the cycle of the beating heart of a zebrafish embryo. We show how this can be used for high-precision prospective gating of fluorescence image slices of the moving heart. We also present initial results demonstrating the application of this technique to 3-D structural imaging of the beating embryonic heart.

  19. Real-time optoacoustic monitoring and three-dimensional mapping of a human arm vasculature

    NASA Astrophysics Data System (ADS)

    Fronheiser, Matthew P.; Ermilov, Sergey A.; Brecht, Hans-Peter; Conjusteau, Andre; Su, Richard; Mehta, Ketan; Oraevsky, Alexander A.

    2010-03-01

    We present our findings from a real-time laser optoacoustic imaging system (LOIS). The system utilizes a Q-switched Nd:YAG laser; a standard 128-channel ultrasonic linear array probe; custom electronics and custom software to collect, process, and display optoacoustic (OA) images at 10 Hz. We propose that this system be used during preoperative mapping of forearm vessels for hemodialysis treatment. To demonstrate the real-time imaging capabilities of the system, we show OA images of forearm vessels in a volunteer and compare our results to ultrasound images of the same region. Our OA images show blood vessels in high contrast. Manipulations with the probe enable us to locate and track arteries and veins of a forearm in real time. We also demonstrate the ability to combine a series of OA image slices into a volume for spatial representation of the vascular network. Finally, we use frame-by-frame analysis of the recorded OA video to measure dynamic changes of the crossection of the ulnar artery.

  20. Elasticity-based three dimensional ultrasound real-time volume rendering

    NASA Astrophysics Data System (ADS)

    Boctor, Emad M.; Matinfar, Mohammad; Ahmad, Omar; Rivaz, Hassan; Choti, Michael; Taylor, Russell H.

    2009-02-01

    Volumetric ultrasound imaging has not gained wide recognition, despite the availability of real-time 3D ultrasound scanners and the anticipated potential of 3D ultrasound imaging in diagnostic and interventional radiology. Their use, however, has been hindered by the lack of real-time visualization methods that are capable of producing high quality 3D rendering of the target/surface of interest. Volume rendering is a known visualization method, which can display clear surfaces out of the acquired volumetric data, and has an increasing number of applications utilizing CT and MRI data. The key element of any volume rendering pipeline is the ability to classify the target/surface of interest by setting an appropriate opacity function. Practical and successful real-time 3D ultrasound volume rendering can be achieved in Obstetrics and Angio applications where setting these opacity functions can be done rapidly, and reliably. Unfortunately, 3D ultrasound volume rendering of soft tissues is a challenging task due to the presence of significant amount of noise and speckle. Recently, several research groups have shown the feasibility of producing 3D elasticity volume from two consecutive 3D ultrasound scans. This report describes a novel volume rendering pipeline utilizing elasticity information. The basic idea is to compute B-mode voxel opacity from the rapidly calculated strain values, which can also be mixed with conventional gradient based opacity function. We have implemented the volume renderer using GPU unit, which gives an update rate of 40 volume/sec.

  1. Annular sizing using real-time three-dimensional intracardiac echocardiography-guided trans-catheter aortic valve replacement

    PubMed Central

    Rendon, Alejandro; Hamid, Tahir; Kanaganayagam, Gajen; Karunaratne, Devinda; Mahadevan, Vaikom S

    2016-01-01

    Objective Transcatheter aortic valve replacement (TAVR) has been established as an alternative therapy for patients with severe aortic stenosis who are unfit for the surgical aortic valve replacements. Pre and periprocedural imaging for the TAVR procedure is the key to procedural success. Currently transesophageal echocardiography (TOE), including real-time three-dimensional (RT-3D) imaging TOE, has been used for peri-interventional monitoring and guidance for TAVR. We describe our initial experience with real-time three-dimensional intracardiac echocardiography (RT-3DICE), imaging technology for the use in the TAVR procedure. Methods We used RT-3DICE using an ACUSON SC2000 2.0v (Siemens Medical Solution), and a 10F AcuNav V catheter (Siemens-Acuson, Inc, Mountain View, California, USA) in addition to preoperative multislice CT (MSCT) in total of five patients undergoing TAVR procedure. Results Aortic annulus and sinus of valsalva diameters were measured using RT-3DICE. Aortic valve measurements obtained using RT-3DICE are comparable to those obtained using MSCT with no significant difference in our patients. Conclusions This small study of five patients shows the safe use of RT-3DICE in TAVR Procedure and may help the procedures performed under local anaesthesia without the need for TOE. PMID:27158522

  2. Real-time telemedicine using shared three-dimensional workspaces over ATM

    NASA Astrophysics Data System (ADS)

    Cahoon, Peter; Forsey, David R.; Hutchison, Susan

    1999-03-01

    During the past five years a high speed ATM network has been developed at UBC that provides a campus testbed, a local testbed to the hospitals, and a National testbed between here and the BADLAB in Ottawa. This testbed has been developed to combine a commercial shared audio/video/whiteboard environment coupled with a shared interactive 3-dimensional solid model. This solid model ranges from a skull reconstructed from a CT scan with muscles and an overlying skin, to a model of the ventricle system of the human brain. Typical interactions among surgeon, radiologist and modeler consist of having image slices of the original scan shared by all and the ability to adjust the surface of the model to conform to each individuals perception of what the final object should look like. The purpose of this interaction can range from forensic reconstruction from partial remains to pre-maxillofacial surgery. A joint project with the forensic unit of the R.C.M.P. in Ottawa using the BADLAB is now in the stages of testing this methodology on a real case beginning with a CT scan of partial remains. A second study underway with the department of Maxiofacial reconstruction at Dalhousie University in Halifax Nova Scotia and concerns a subject who is about to undergo orthognathic surgery, in particular a mandibular advancement. This subject has been MRI scanned, a solid model constructed of the mandible and the virtual surgery constructed on the model. This model and the procedure have been discussed and modified by the modeler and the maxillofacial specialist using these shared workspaces. The procedure will be repeated after the actual surgery to verify the modeled procedure. The advantage of this technique is that none of the specialists need be in the same room, or city. Given the scarcity of time and specialists this methodology shows great promise. In November of this last year a shared live demonstration of this facial modeler was done between Vancouver and Dalhousie University in

  3. Fast interactive real-time volume rendering of real-time three-dimensional echocardiography: an implementation for low-end computers

    NASA Technical Reports Server (NTRS)

    Saracino, G.; Greenberg, N. L.; Shiota, T.; Corsi, C.; Lamberti, C.; Thomas, J. D.

    2002-01-01

    Real-time three-dimensional echocardiography (RT3DE) is an innovative cardiac imaging modality. However, partly due to lack of user-friendly software, RT3DE has not been widely accepted as a clinical tool. The object of this study was to develop and implement a fast and interactive volume renderer of RT3DE datasets designed for a clinical environment where speed and simplicity are not secondary to accuracy. Thirty-six patients (20 regurgitation, 8 normal, 8 cardiomyopathy) were imaged using RT3DE. Using our newly developed software, all 3D data sets were rendered in real-time throughout the cardiac cycle and assessment of cardiac function and pathology was performed for each case. The real-time interactive volume visualization system is user friendly and instantly provides consistent and reliable 3D images without expensive workstations or dedicated hardware. We believe that this novel tool can be used clinically for dynamic visualization of cardiac anatomy.

  4. Shaping volumetric light distribution through turbid media using real-time three-dimensional opto-acoustic feedback.

    PubMed

    Deán-Ben, X Luís; Estrada, Héctor; Razansky, Daniel

    2015-02-15

    Focusing light through turbid media represents a highly fascinating challenge in modern biophotonics. The unique capability of opto-acoustics for high-resolution imaging of light absorption contrast in deep tissues can provide a natural and efficient feedback to control light delivery in a scattering medium. While the basic feasibility of using opto-acoustic readings as a feedback mechanism for wavefront shaping has been recently reported, the suggested approaches may require long acquisition times, making them challenging to be translated into realistic tissue environments. In an attempt to significantly accelerate dynamic wavefront shaping capabilities, we present here a feedback-based approach using real-time three-dimensional opto-acoustic imaging assisted with genetic-algorithm-based optimization. The new technique offers robust performance in the presence of noisy measurements and can simultaneously control the scattered wave field in an entire volumetric region. PMID:25680120

  5. Real-time three-dimensional optical coherence tomography image-guided core-needle biopsy system

    PubMed Central

    Kuo, Wei-Cheng; Kim, Jongsik; Shemonski, Nathan D.; Chaney, Eric J.; Spillman, Darold R.; Boppart, Stephen A.

    2012-01-01

    Advances in optical imaging modalities, such as optical coherence tomography (OCT), enable us to observe tissue microstructure at high resolution and in real time. Currently, core-needle biopsies are guided by external imaging modalities such as ultrasound imaging and x-ray computed tomography (CT) for breast and lung masses, respectively. These image-guided procedures are frequently limited by spatial resolution when using ultrasound imaging, or by temporal resolution (rapid real-time feedback capabilities) when using x-ray CT. One feasible approach is to perform OCT within small gauge needles to optically image tissue microstructure. However, to date, no system or core-needle device has been developed that incorporates both three-dimensional OCT imaging and tissue biopsy within the same needle for true OCT-guided core-needle biopsy. We have developed and demonstrate an integrated core-needle biopsy system that utilizes catheter-based 3-D OCT for real-time image-guidance for target tissue localization, imaging of tissue immediately prior to physical biopsy, and subsequent OCT imaging of the biopsied specimen for immediate assessment at the point-of-care. OCT images of biopsied ex vivo tumor specimens acquired during core-needle placement are correlated with corresponding histology, and computational visualization of arbitrary planes within the 3-D OCT volumes enables feedback on specimen tissue type and biopsy quality. These results demonstrate the potential for using real-time 3-D OCT for needle biopsy guidance by imaging within the needle and tissue during biopsy procedures. PMID:22741064

  6. Real-Time Three-Dimensional Cell Segmentation in Large-Scale Microscopy Data of Developing Embryos.

    PubMed

    Stegmaier, Johannes; Amat, Fernando; Lemon, William C; McDole, Katie; Wan, Yinan; Teodoro, George; Mikut, Ralf; Keller, Philipp J

    2016-01-25

    We present the Real-time Accurate Cell-shape Extractor (RACE), a high-throughput image analysis framework for automated three-dimensional cell segmentation in large-scale images. RACE is 55-330 times faster and 2-5 times more accurate than state-of-the-art methods. We demonstrate the generality of RACE by extracting cell-shape information from entire Drosophila, zebrafish, and mouse embryos imaged with confocal and light-sheet microscopes. Using RACE, we automatically reconstructed cellular-resolution tissue anisotropy maps across developing Drosophila embryos and quantified differences in cell-shape dynamics in wild-type and mutant embryos. We furthermore integrated RACE with our framework for automated cell lineaging and performed joint segmentation and cell tracking in entire Drosophila embryos. RACE processed these terabyte-sized datasets on a single computer within 1.4 days. RACE is easy to use, as it requires adjustment of only three parameters, takes full advantage of state-of-the-art multi-core processors and graphics cards, and is available as open-source software for Windows, Linux, and Mac OS. PMID:26812020

  7. Microvascular anastomosis guidance and evaluation using real-time three-dimensional Fourier-domain Doppler optical coherence tomography

    PubMed Central

    Ibrahim, Zuhaib; Tong, Dedi; Zhu, Shan; Mao, Qi; Pang, John; Andrew Lee, Wei Ping; Brandacher, Gerald; Kang, Jin U.

    2013-01-01

    Abstract. Vascular and microvascular anastomoses are critical components of reconstructive microsurgery, vascular surgery, and transplant surgery. Intraoperative surgical guidance using a surgical imaging modality that provides an in-depth view and three-dimensional (3-D) imaging can potentially improve outcome following both conventional and innovative anastomosis techniques. Objective postoperative imaging of the anastomosed vessel can potentially improve the salvage rate when combined with other clinical assessment tools, such as capillary refill, temperature, blanching, and skin turgor. Compared to other contemporary postoperative monitoring modalities—computed tomography angiograms, magnetic resonance (MR) angiograms, and ultrasound Doppler—optical coherence tomography (OCT) is a noninvasive high-resolution (micron-level), high-speed, 3-D imaging modality that has been adopted widely in biomedical and clinical applications. For the first time, to the best of our knowledge, the feasibility of real-time 3-D phase-resolved Doppler OCT (PRDOCT) as an assisted intra- and postoperative imaging modality for microvascular anastomosis of rodent femoral vessels is demonstrated, which will provide new insights and a potential breakthrough to microvascular and supermicrovascular surgery. PMID:23856833

  8. The advantages of live/real time three-dimensional transesophageal echocardiography in the assessment of tricuspid valve infective endocarditis.

    PubMed

    Sungur, Aylin; Hsiung, Ming C; Meggo Quiroz, Luis D; Oz, Tuğba Kemaloğlu; Haj Asaad, Ayman; Joshi, Deepak; Dönmez, Cevdet; Güvenç, Tolga S; Nanda, Navin C

    2014-11-01

    Currently, tricuspid valve infective endocarditis (TVIE) is encountered in daily clinical practice more frequently due to the increasing prevalence of illicit intravenous drug use and the implantation of intracardiac devices. In this study, we compared findings from intra-operative live/real time three-dimensional transesophageal echocardiograms (3DTEE) and two-dimensional transesophageal echocardiograms (2DTEE) of 10 patients who underwent surgery for native tricuspid valve (TV) endocarditis. Unlike 2DTEE, 3DTEE allowed en face visualization of the 3 TV leaflets from both, atrial and ventricular aspects, in 9 of the 10 cases. In the remaining patient, in whom 3DTEE could not identify all 3 leaflets en face, the TV was found essentially destroyed at surgery. Using 3DTEE, the number of vegetations was accurately reported when compared with the surgical record. Furthermore, the orientation of each vegetation was the same as noted in the surgical findings. 2DTEE missed the identification of vegetations in 5 patients. The attachment site of vegetations to the TV were also not characterized by 2DTEE in 5 patients. In all 10 cases, 3DTEE characterized the vegetations more accurately with larger dimensions, including those in the azimuthal axis, and volumes. In addition, a perivalvular abscess that lead to surgical intervention was identified by 3DTEE, however, missed by 2DTEE. In conclusion, 3DTEE allows en face visualization of the TV apparatus permitting accurate description of the number and dimensions of vegetations identified by our surgical standard, which ultimately informs patients' prognosis and dictates the timing and planning for surgical intervention. Its use should be in conjunction with 2DTEE when evaluating TVIE.

  9. Validation of admittance computed left ventricular volumes against real-time three-dimensional echocardiography in the porcine heart.

    PubMed

    Kutty, Shelby; Kottam, Anil T; Padiyath, Asif; Bidasee, Keshore R; Li, Ling; Gao, Shunji; Wu, Juefei; Lof, John; Danford, David A; Kuehne, Titus

    2013-06-01

    The admittance and Wei's equation is a new technique for ventricular volumetry to determine pressure-volume relations that addresses traditional conductance-related issues of parallel conductance and field correction factor. These issues with conductance have prevented researchers from obtaining real-time absolute ventricular volumes. Moreover, the time-consuming steps involved in processing conductance catheter data warrant the need for a better catheter-based technique for ventricular volumetry. We aimed to compare the accuracy of left ventricular (LV) volumetry between the new admittance catheterization technique and transoesophageal real-time three-dimensional echocardiography (RT3DE) in a large-animal model. Eight anaesthetized pigs were used. A 7 French admittance catheter was positioned in the LV via the right carotid artery. The catheter was connected to an admittance control unit (ADVantage; Transonic Scisense Inc.), and data were recorded on a four-channel acquisition system (FA404; iWorx Systems). Admittance catheterization data and transoesophageal RT3DE (X7-2; Philips) data were simultaneously obtained with the animal ventilated, under neuromuscular blockade and monitored in baseline conditions and during dobutamine infusion. Left ventricular volumes measured from admittance catheterization (Labscribe; iWorx Systems) and RT3DE (Qlab; Philips) were compared. In a subset of four animals, admittance volumes were compared with those obtained from traditional conductance catheterization (MPVS Ultra; Millar Instruments). Of 37 sets of measurements compared, admittance- and RT3DE-derived LV volumes and ejection fractions at baseline and in the presence of dobutamine exhibited general agreement, with mean percentage intermethod differences of 10% for end-diastolic volumes, 14% for end-systolic volumes and 9% for ejection fraction; the respective intermethod differences between admittance and conductance in eight data sets compared were 11, 11 and 12

  10. Evaluation of the right ventricular function in pneumoconiosis patients using volume-time curves obtained by real-time three-dimensional echocardiography.

    PubMed

    Shi, Doufei; Zhang, Jie; Liu, Xinkai; Zhang, Gang; Cui, Lianqun

    2014-12-01

    The study was aimed to evaluate the right ventricular function in pneumoconiosis patients by real-time three-dimensional echocardiography. A total of 80 individuals including 44 consecutive pneumoconiosis patients and 36 age- and gender-matched healthy volunteers as controls were prospectively recruited for the study. All the patients underwent two- and three-dimensional echocardiography. Measurements of the right ventricle included tricuspid regurgitation pressure (TRPG), anterior and posterior wall thickness and range of motion (TH1, TH2, M1, M2), right end-diastolic volume and end-systolic volume. The right ventricular ejection fraction (RVEF) was also calculated. The RVEF of healthy volunteers ranged from 50 to 78 %, whereas that of the pneumoconiosis patients varied from 29 to 73 %. An increase in TRPG caused a significant (p = 0.006) decrease in RVEF (by 77.3 %), suggesting the two variables were negatively correlated (r = -0.643, p < 0.01). In comparison with normal, the volume-time curves of the pneumoconiosis patients showed a lower trough. Use of real-time three-dimensional echocardiography provides with added clinical information needed to evaluate right ventricular function in pneumoconiosis patients.

  11. Evaluation of mitral valve prolapse using newly developed real-time three-dimensional echocardiographic system with real-time volume rendering.

    PubMed

    Goktekin, Omer; Matsumura, Makoto; Omoto, Ryozo; Kyo, Shunei; Mochizuki, Tsuyoshi

    2003-02-01

    The development of a real-time three-dimensional (RT3D) image acquisition system and direct digital links between ultrasound equipment and the data processing computer facilitate improved 3D image reconstruction. However, at present time, it is hard to promptly display 3D images and is also ineffective for a practical use. The objective of this study was to assess the feasibility of a new transthoracic RT3D echocardiographic system for evaluation of mitral valve prolapse. Eighteen patients with mitral valve prolapse diagnosed by transthoracic two-dimensional (2D) echocardiography and M-mode were examined through this technique (11 male, mean age 42 +/- 17 years). Since visualization of mitral valve from apical four-chamber view was better than that of the parasternal approach, only apical approach was used for mitral valve evaluation. This system is capable of acquiring volumetric data from mechanical scanning of the phased-array transducer (3.5 MHz) as well as displaying the volume rendered images of the structure without storing the image data and reconstruction of the object. The prolapse of leaflet could be seen in 14/ 18 (77%) of patients with mitral valve prolapse based on conventional echocardiography. The newly developed transthoracic RT 3D ultrasound system without a reconstruction process seemed to be a useful noninvasive tool for diagnosis of mitral valve prolapse and detection of prolapsed leaflet or scallop, which is very important for deciding on a reliable surgical technique.

  12. Accuracy of a Real-Time, Computerized, Binocular, Three-Dimensional Trajectory-Tracking Device for Recording Functional Mandibular Movements

    PubMed Central

    Zhao, Tian; Yang, Huifang; Sui, Huaxin; Salvi, Satyajeet Sudhir; Wang, Yong; Sun, Yuchun

    2016-01-01

    Objective Developments in digital technology have permitted researchers to study mandibular movements. Here, the accuracy of a real-time, computerized, binocular, three-dimensional (3D) trajectory-tracking device for recording functional mandibular movements was evaluated. Methods An occlusal splint without the occlusal region was created based on a plaster cast of the lower dentition. The splint was rigidly connected with a target on its labial side and seated on the cast. The cast was then rigidly attached to the stage of a high-precision triaxial electronic translator, which was used to move the target-cast-stage complex. Half-circular movements (5.00-mm radius) in three planes (XOY, XOZ, YOZ) and linear movements along the x-axis were performed at 5.00 mm/s. All trajectory points were recorded with the binocular 3D trajectory-tracking device and fitted to arcs or lines, respectively, with the Imageware software. To analyze the accuracy of the trajectory-tracking device, the mean distances between the trajectory points and the fitted arcs or lines were measured, and the mean differences between the lengths of the fitted arcs’ radii and a set value (5.00 mm) were then calculated. A one-way analysis of variance was used to evaluate the spatial consistency of the recording accuracy in three different planes. Results The mean distances between the trajectory points and fitted arcs or lines were 0.076 ± 0.033 mm or 0.089 ± 0.014 mm. The mean difference between the lengths of the fitted arcs’ radii and the set value (5.00 mm) was 0.025 ± 0.071 mm. A one-way ANOVA showed that the recording errors in three different planes were not statistically significant. Conclusion These results suggest that the device can record certain movements at 5.00 mm/s, which is similar to the speed of functional mandibular movements. In addition, the recordings had an error of <0.1 mm and good spatial consistency. Thus, the device meets some of the requirements necessary for

  13. A study of the application of singular perturbation theory. [development of a real time algorithm for optimal three dimensional aircraft maneuvers

    NASA Technical Reports Server (NTRS)

    Mehra, R. K.; Washburn, R. B.; Sajan, S.; Carroll, J. V.

    1979-01-01

    A hierarchical real time algorithm for optimal three dimensional control of aircraft is described. Systematic methods are developed for real time computation of nonlinear feedback controls by means of singular perturbation theory. The results are applied to a six state, three control variable, point mass model of an F-4 aircraft. Nonlinear feedback laws are presented for computing the optimal control of throttle, bank angle, and angle of attack. Real Time capability is assessed on a TI 9900 microcomputer. The breakdown of the singular perturbation approximation near the terminal point is examined Continuation methods are examined to obtain exact optimal trajectories starting from the singular perturbation solutions.

  14. Real-time in situ three-dimensional integral videography and surgical navigation using augmented reality: a pilot study.

    PubMed

    Suenaga, Hideyuki; Hoang Tran, Huy; Liao, Hongen; Masamune, Ken; Dohi, Takeyoshi; Hoshi, Kazuto; Mori, Yoshiyuki; Takato, Tsuyoshi

    2013-06-01

    To evaluate the feasibility and accuracy of a three-dimensional augmented reality system incorporating integral videography for imaging oral and maxillofacial regions, based on preoperative computed tomography data. Three-dimensional surface models of the jawbones, based on the computed tomography data, were used to create the integral videography images of a subject's maxillofacial area. The three-dimensional augmented reality system (integral videography display, computed tomography, a position tracker and a computer) was used to generate a three-dimensional overlay that was projected on the surgical site via a half-silvered mirror. Thereafter, a feasibility study was performed on a volunteer. The accuracy of this system was verified on a solid model while simulating bone resection. Positional registration was attained by identifying and tracking the patient/surgical instrument's position. Thus, integral videography images of jawbones, teeth and the surgical tool were superimposed in the correct position. Stereoscopic images viewed from various angles were accurately displayed. Change in the viewing angle did not negatively affect the surgeon's ability to simultaneously observe the three-dimensional images and the patient, without special glasses. The difference in three-dimensional position of each measuring point on the solid model and augmented reality navigation was almost negligible (<1 mm); this indicates that the system was highly accurate. This augmented reality system was highly accurate and effective for surgical navigation and for overlaying a three-dimensional computed tomography image on a patient's surgical area, enabling the surgeon to understand the positional relationship between the preoperative image and the actual surgical site, with the naked eye.

  15. Assessment of visual quality and spatial accuracy of fast anisotropic diffusion and scan conversion algorithms for real-time three-dimensional spherical ultrasound

    NASA Astrophysics Data System (ADS)

    Duan, Qi; Angelini, Elsa D.; Laine, Andrew

    2004-04-01

    Three-dimensional ultrasound machines based on matrix phased-array transducers are gaining predominance for real-time dynamic screening in cardiac and obstetric practice. These transducers array acquire three-dimensional data in spherical coordinates along lines tiled in azimuth and elevation angles at incremental depth. This study aims at evaluating fast filtering and scan conversion algorithms applied in the spherical domain prior to visualization into Cartesian coordinates for visual quality and spatial measurement accuracy. Fast 3d scan conversion algorithms were implemented and with different order interpolation kernels. Downsizing and smoothing of sampling artifacts were integrated in the scan conversion process. In addition, a denoising scheme for spherical coordinate data with 3d anisotropic diffusion was implemented and applied prior to scan conversion to improve image quality. Reconstruction results under different parameter settings, such as different interpolation kernels, scaling factor, smoothing options, and denoising, are reported. Image quality was evaluated on several data sets via visual inspections and measurements of cylinder objects dimensions. Error measurements of the cylinder's radius, reported in this paper, show that the proposed fast scan conversion algorithm can correctly reconstruct three-dimensional ultrasound in Cartesian coordinates under tuned parameter settings. Denoising via three-dimensional anisotropic diffusion was able to greatly improve the quality of resampled data without affecting the accuracy of spatial information after the modification of the introduction of a variable gradient threshold parameter.

  16. Initial clinical experience of real-time three-dimensional echocardiography in patients with ischemic and idiopathic dilated cardiomyopathy

    NASA Technical Reports Server (NTRS)

    Shiota, T.; McCarthy, P. M.; White, R. D.; Qin, J. X.; Greenberg, N. L.; Flamm, S. D.; Wong, J.; Thomas, J. D.

    1999-01-01

    The geometry of the left ventricle in patients with cardiomyopathy is often sub-optimal for 2-dimensional ultrasound when assessing left ventricular (LV) function and localized abnormalities such as a ventricular aneurysm. The aim of this study was to report the initial experience of real-time 3-D echocardiography for evaluating patients with cardiomyopathy. A total of 34 patients were evaluated with the real-time 3D method in the operating room (n = 15) and in the echocardiographic laboratory (n = 19). Thirteen of 28 patients with cardiomyopathy and 6 other subjects with normal LV function were evaluated by both real-time 3-D echocardiography and magnetic resonance imaging (MRI) for obtaining LV volumes and ejection fractions for comparison. There were close relations and agreements for LV volumes (r = 0.98, p <0.0001, mean difference = -15 +/- 81 ml) and ejection fractions (r = 0.97, p <0.0001, mean difference = 0.001 +/- 0.04) between the real-time 3D method and MRI when 3 cardiomyopathy cases with marked LV dilatation (LV end-diastolic volume >450 ml by MRI) were excluded. In these 3 patients, 3D echocardiography significantly underestimated the LV volumes due to difficulties with imaging the entire LV in a 60 degrees x 60 degrees pyramidal volume. The new real-time 3D echocardiography is feasible in patients with cardiomyopathy and may provide a faster and lower cost alternative to MRI for evaluating cardiac function in patients.

  17. Real-time three-dimensional imaging of epidermal splitting and removal by high-definition optical coherence tomography.

    PubMed

    Boone, Marc; Draye, Jean Pierre; Verween, Gunther; Pirnay, Jean-Paul; Verbeken, Gilbert; De Vos, Daniel; Rose, Thomas; Jennes, Serge; Jemec, Gregor B E; Del Marmol, Véronique

    2014-10-01

    While real-time 3-D evaluation of human skin constructs is needed, only 2-D non-invasive imaging techniques are available. The aim of this paper is to evaluate the potential of high-definition optical coherence tomography (HD-OCT) for real-time 3-D assessment of the epidermal splitting and decellularization. Human skin samples were incubated with four different agents: Dispase II, NaCl 1 M, sodium dodecyl sulphate (SDS) and Triton X-100. Epidermal splitting, dermo-epidermal junction, acellularity and 3-D architecture of dermal matrices were evaluated by High-definition optical coherence tomography before and after incubation. Real-time 3-D HD-OCT assessment was compared with 2-D en face assessment by reflectance confocal microscopy (RCM). (Immuno) histopathology was used as control. HD-OCT imaging allowed real-time 3-D visualization of the impact of selected agents on epidermal splitting, dermo-epidermal junction, dermal architecture, vascular spaces and cellularity. RCM has a better resolution (1 μm) than HD-OCT (3 μm), permitting differentiation of different collagen fibres, but HD-OCT imaging has deeper penetration (570 μm) than RCM imaging (200 μm). Dispase II and NaCl treatments were found to be equally efficient in the removal of the epidermis from human split-thickness skin allografts. However, a different epidermal splitting level at the dermo-epidermal junction could be observed and confirmed by immunolabelling of collagen type IV and type VII. Epidermal splitting occurred at the level of the lamina densa with dispase II and above the lamina densa (in the lamina lucida) with NaCl. The 3-D architecture of dermal papillae and dermis was more affected by Dispase II on HD-OCT which corresponded with histopathologic (orcein staining) fragmentation of elastic fibres. With SDS treatment, the epidermal removal was incomplete as remnants of the epidermal basal cell layer remained attached to the basement membrane on the dermis. With Triton X-100 treatment

  18. Real time three-dimensional space video rate sensors for millimeter waves imaging based very inexpensive plasma LED lamps

    NASA Astrophysics Data System (ADS)

    Levanon, Assaf; Yitzhaky, Yitzhak; Kopeika, Natan S.; Rozban, Daniel; Abramovich, Amir

    2014-10-01

    In recent years, much effort has been invested to develop inexpensive but sensitive Millimeter Wave (MMW) detectors that can be used in focal plane arrays (FPAs), in order to implement real time MMW imaging. Real time MMW imaging systems are required for many varied applications in many fields as homeland security, medicine, communications, military products and space technology. It is mainly because this radiation has high penetration and good navigability through dust storm, fog, heavy rain, dielectric materials, biological tissue, and diverse materials. Moreover, the atmospheric attenuation in this range of the spectrum is relatively low and the scattering is also low compared to NIR and VIS. The lack of inexpensive room temperature imaging systems makes it difficult to provide a suitable MMW system for many of the above applications. In last few years we advanced in research and development of sensors using very inexpensive (30-50 cents) Glow Discharge Detector (GDD) plasma indicator lamps as MMW detectors. This paper presents three kinds of GDD sensor based lamp Focal Plane Arrays (FPA). Those three kinds of cameras are different in the number of detectors, scanning operation, and detection method. The 1st and 2nd generations are 8 × 8 pixel array and an 18 × 2 mono-rail scanner array respectively, both of them for direct detection and limited to fixed imaging. The last designed sensor is a multiplexing frame rate of 16x16 GDD FPA. It permits real time video rate imaging of 30 frames/ sec and comprehensive 3D MMW imaging. The principle of detection in this sensor is a frequency modulated continuous wave (FMCW) system while each of the 16 GDD pixel lines is sampled simultaneously. Direct detection is also possible and can be done with a friendly user interface. This FPA sensor is built over 256 commercial GDD lamps with 3 mm diameter International Light, Inc., Peabody, MA model 527 Ne indicator lamps as pixel detectors. All three sensors are fully supported

  19. Incremental value of live/real time three-dimensional transesophageal echocardiography over the two-dimensional technique in the assessment of aortic atherosclerotic thrombi and ulcers.

    PubMed

    Elsayed, Mahmoud; Bulur, Serkan; Kalla, Aditi; Ahmed, Mustafa I; Hsiung, Ming C; Uygur, Begum; Alagic, Nermina; Sungur, Aylin; Singh, Satinder; Nanda, Navin C

    2016-08-01

    We present two cases in whom live/real time three-dimensional transesophageal echocardiography (3DTEE) provided incremental value in the assessment of atherosclerotic disease in the aorta. In one patient, it identified additional atherosclerotic ulcers as well as thrombi within them which were missed by two-dimensional (2D) TEE. In both cases, the size of the large mobile atherosclerotic plaque was underestimated by 2DTEE as compared with 3DTEE. Furthermore, 3DTEE provided volume quantification of the thrombi and ulcers which is not possible by 2DTEE. The echocardiographic findings of atherosclerotic plaques were confirmed by computed tomography in one patient and by surgery in the other.

  20. Using volume-time curves with real-time three-dimensional echocardiography to analyze right ventricular function in patients with pneumoconiosis.

    PubMed

    Wei, D M; Ding, Y; He, W

    2014-11-14

    We evaluated right ventricular function in patients with pneumoconiosis using real-time three-dimensional echocardiography (RT3DE). A total of 80 consecutive patients were prospectively recruited, 44 of whom were diagnosed with pneumoconiosis, and the remaining 36 age- and gender-matched healthy volunteers served as the control group. All patients underwent both 2D and 3DE. The tricuspid regurgitation pressure (TRPG), right ventricular anterior wall thickness and range of motion, right ventricular posterior wall thickness and range of motion, right ventricular end-diastolic volume, right ventricular end-systolic volume, and right ventricular ejection fraction (RVEF) were measured. The RVEF of healthy volunteers ranged from 50 to 78%, while the RVEF of pneumoconiosis patients ranged from 29 to 73%. TRPG influenced RVEF by 77.3% (P = 0.006) and showed a negative correlation (r = -0.643, P < 0.01). Volume-time curves (VTC) of patients with pneumoconiosis showed more troughs (low stroke volumes) than the VTCs of normal subjects. Evaluation of right ventricular function in patients with pneumoconiosis using RT3DE can provide additional clinical information.

  1. Real-time three-dimensional echocardiographic study of left ventricular function after infarct exclusion surgery for ischemic cardiomyopathy

    NASA Technical Reports Server (NTRS)

    Qin, J. X.; Shiota, T.; McCarthy, P. M.; Firstenberg, M. S.; Greenberg, N. L.; Tsujino, H.; Bauer, F.; Travaglini, A.; Hoercher, K. J.; Buda, T.; Smedira, N. G.; Thomas, J. D.

    2000-01-01

    BACKGROUND: Infarct exclusion (IE) surgery, a technique of left ventricular (LV) reconstruction for dyskinetic or akinetic LV segments in patients with ischemic cardiomyopathy, requires accurate volume quantification to determine the impact of surgery due to complicated geometric changes. METHODS AND RESULTS: Thirty patients who underwent IE (mean age 61+/-8 years, 73% men) had epicardial real-time 3-dimensional echocardiographic (RT3DE) studies performed before and after IE. RT3DE follow-up was performed transthoracically 42+/-67 days after surgery in 22 patients. Repeated measures ANOVA was used to compare the values before and after IE surgery and at follow-up. Significant decreases in LV end-diastolic (EDVI) and end-systolic (ESVI) volume indices were apparent immediately after IE and in follow-up (EDVI 99+/-40, 67+/-26, and 71+/-31 mL/m(2), respectively; ESVI 72+/-37, 40+/-21, and 42+/-22 mL/m(2), respectively; P:<0.05). LV ejection fraction increased significantly and remained higher (0.29+/-0.11, 0.43+/-0.13, and 0.42+/-0.09, respectively, P:<0.05). Forward stroke volume in 16 patients with preoperative mitral regurgitation significantly improved after IE and in follow-up (22+/-12, 53+/-24, and 58+/-21 mL, respectively, P:<0.005). New York Heart Association functional class at an average 285+/-144 days of clinical follow-up significantly improved from 3.0+/-0.8 to 1.8+/-0.8 (P:<0.0001). Smaller end-diastolic and end-systolic volumes measured with RT3DE immediately after IE were closely related to improvement in New York Heart Association functional class at clinical follow-up (Spearman's rho=0.58 and 0.60, respectively). CONCLUSIONS: RT3DE can be used to quantitatively assess changes in LV volume and function after complicated LV reconstruction. Decreased LV volume and increased ejection fraction imply a reduction in LV wall stress after IE surgery and are predictive of symptomatic improvement.

  2. New digital measurement methods for left ventricular volume using real-time three-dimensional echocardiography: comparison with electromagnetic flow method and magnetic resonance imaging

    NASA Technical Reports Server (NTRS)

    Qin, J. J.; Jones, M.; Shiota, T.; Greenberg, N. L.; Firstenberg, M. S.; Tsujino, H.; Zetts, A. D.; Sun, J. P.; Cardon, L. A.; Odabashian, J. A.; Flamm, S. D.; White, R. D.; Panza, J. A.; Thomas, J. D.

    2000-01-01

    AIM: The aim of this study was to investigate the feasibility and accuracy of using symmetrically rotated apical long axis planes for the determination of left ventricular (LV) volumes with real-time three-dimensional echocardiography (3DE). METHODS AND RESULTS: Real-time 3DE was performed in six sheep during 24 haemodynamic conditions with electromagnetic flow measurements (EM), and in 29 patients with magnetic resonance imaging measurements (MRI). LV volumes were calculated by Simpson's rule with five 3DE methods (i.e. apical biplane, four-plane, six-plane, nine-plane (in which the angle between each long axis plane was 90 degrees, 45 degrees, 30 degrees or 20 degrees, respectively) and standard short axis views (SAX)). Real-time 3DE correlated well with EM for LV stroke volumes in animals (r=0.68-0.95) and with MRI for absolute volumes in patients (r-values=0.93-0.98). However, agreement between MRI and apical nine-plane, six-plane, and SAX methods in patients was better than those with apical four-plane and bi-plane methods (mean difference = -15, -18, -13, vs. -31 and -48 ml for end-diastolic volume, respectively, P<0.05). CONCLUSION: Apically rotated measurement methods of real-time 3DE correlated well with reference standards for calculating LV volumes. Balancing accuracy and required time for these LV volume measurements, the apical six-plane method is recommended for clinical use.

  3. Pixel multiplexing technique for real-time three-dimensional-imaging laser detection and ranging system using four linear-mode avalanche photodiodes.

    PubMed

    Xu, Fan; Wang, Yuanqing; Li, Fenfang

    2016-03-01

    The avalanche-photodiode-array (APD-array) laser detection and ranging (LADAR) system has been continually developed owing to its superiority of nonscanning, large field of view, high sensitivity, and high precision. However, how to achieve higher-efficient detection and better integration of the LADAR system for real-time three-dimensional (3D) imaging continues to be a problem. In this study, a novel LADAR system using four linear mode APDs (LmAPDs) is developed for high-efficient detection by adopting a modulation and multiplexing technique. Furthermore, an automatic control system for the array LADAR system is proposed and designed by applying the virtual instrumentation technique. The control system aims to achieve four functions: synchronization of laser emission and rotating platform, multi-channel synchronous data acquisition, real-time Ethernet upper monitoring, and real-time signal processing and 3D visualization. The structure and principle of the complete system are described in the paper. The experimental results demonstrate that the LADAR system is capable of achieving real-time 3D imaging on an omnidirectional rotating platform under the control of the virtual instrumentation system. The automatic imaging LADAR system utilized only 4 LmAPDs to achieve 256-pixel-per-frame detection with by employing 64-bit demodulator. Moreover, the lateral resolution is ∼15 cm and range accuracy is ∼4 cm root-mean-square error at a distance of ∼40 m.

  4. Pixel multiplexing technique for real-time three-dimensional-imaging laser detection and ranging system using four linear-mode avalanche photodiodes

    NASA Astrophysics Data System (ADS)

    Xu, Fan; Wang, Yuanqing; Li, Fenfang

    2016-03-01

    The avalanche-photodiode-array (APD-array) laser detection and ranging (LADAR) system has been continually developed owing to its superiority of nonscanning, large field of view, high sensitivity, and high precision. However, how to achieve higher-efficient detection and better integration of the LADAR system for real-time three-dimensional (3D) imaging continues to be a problem. In this study, a novel LADAR system using four linear mode APDs (LmAPDs) is developed for high-efficient detection by adopting a modulation and multiplexing technique. Furthermore, an automatic control system for the array LADAR system is proposed and designed by applying the virtual instrumentation technique. The control system aims to achieve four functions: synchronization of laser emission and rotating platform, multi-channel synchronous data acquisition, real-time Ethernet upper monitoring, and real-time signal processing and 3D visualization. The structure and principle of the complete system are described in the paper. The experimental results demonstrate that the LADAR system is capable of achieving real-time 3D imaging on an omnidirectional rotating platform under the control of the virtual instrumentation system. The automatic imaging LADAR system utilized only 4 LmAPDs to achieve 256-pixel-per-frame detection with by employing 64-bit demodulator. Moreover, the lateral resolution is ˜15 cm and range accuracy is ˜4 cm root-mean-square error at a distance of ˜40 m.

  5. Pixel multiplexing technique for real-time three-dimensional-imaging laser detection and ranging system using four linear-mode avalanche photodiodes.

    PubMed

    Xu, Fan; Wang, Yuanqing; Li, Fenfang

    2016-03-01

    The avalanche-photodiode-array (APD-array) laser detection and ranging (LADAR) system has been continually developed owing to its superiority of nonscanning, large field of view, high sensitivity, and high precision. However, how to achieve higher-efficient detection and better integration of the LADAR system for real-time three-dimensional (3D) imaging continues to be a problem. In this study, a novel LADAR system using four linear mode APDs (LmAPDs) is developed for high-efficient detection by adopting a modulation and multiplexing technique. Furthermore, an automatic control system for the array LADAR system is proposed and designed by applying the virtual instrumentation technique. The control system aims to achieve four functions: synchronization of laser emission and rotating platform, multi-channel synchronous data acquisition, real-time Ethernet upper monitoring, and real-time signal processing and 3D visualization. The structure and principle of the complete system are described in the paper. The experimental results demonstrate that the LADAR system is capable of achieving real-time 3D imaging on an omnidirectional rotating platform under the control of the virtual instrumentation system. The automatic imaging LADAR system utilized only 4 LmAPDs to achieve 256-pixel-per-frame detection with by employing 64-bit demodulator. Moreover, the lateral resolution is ∼15 cm and range accuracy is ∼4 cm root-mean-square error at a distance of ∼40 m. PMID:27036763

  6. Real-Time Bioluminescence Imaging of Cell Distribution, Growth, and Differentiation in a Three-Dimensional Scaffold Under Interstitial Perfusion for Tissue Engineering.

    PubMed

    Vila, Olaia F; Garrido, Cristina; Cano, Irene; Guerra-Rebollo, Marta; Navarro, Melba; Meca-Cortés, Oscar; Ma, Stephen P; Engel, Elisabeth; Rubio, Nuria; Blanco, Jerónimo

    2016-09-01

    Bioreactor systems allow safe and reproducible production of tissue constructs and functional analysis of cell behavior in biomaterials. However, current procedures for the analysis of tissue generated in biomaterials are destructive. We describe a transparent perfusion system that allows real-time bioluminescence imaging of luciferase expressing cells seeded in scaffolds for the study of cell-biomaterial interactions and bioreactor performance. A prototype provided with a poly(lactic) acid scaffold was used for "proof of principle" studies to monitor cell survival in the scaffold (up to 22 days). Moreover, using cells expressing a luciferase reporter under the control of inducible tissue-specific promoters, it was possible to monitor changes in gene expression resulting from hypoxic state and endothelial cell differentiation. This system should be useful in numerous tissue engineering applications, the optimization of bioreactor operation conditions, and the analysis of cell behavior in three-dimensional scaffolds. PMID:27339005

  7. Impact of left ventricular outflow tract area on systolic outflow velocity in hypertrophic cardiomyopathy: a real-time three-dimensional echocardiographic study

    NASA Technical Reports Server (NTRS)

    Qin, Jian Xin; Shiota, Takahiro; Lever, Harry M.; Rubin, David N.; Bauer, Fabrice; Kim, Yong Jin; Sitges, Marta; Greenberg, Neil L.; Drinko, Jeanne K.; Martin, Maureen; Agler, Deborah A.; Thomas, James D.

    2002-01-01

    OBJECTIVES: The aim of this study was to use real-time three-dimensional echocardiography (3DE) to investigate the quantitative relation between minimal left ventricular (LV) outflow tract area (A(LVOT)) and maximal LV outflow tract (LVOT) velocity in patients with hypertrophic obstructive cardiomyopathy (HCM). BACKGROUND: In patients with HCM, LVOT velocity should change inversely with minimal A(LVOT) unless LVOT obstruction reduces the pumping capacity of the ventricle. METHODS: A total of 25 patients with HCM with systolic anterior motion (SAM) of the mitral valve leaflets underwent real-time 3DE. The smallest A(LVOT) during systole was measured using anatomically oriented two-dimensional "C-planes" within the pyramidal 3DE volume. Maximal velocity across LVOT was evaluated by two-dimensional Doppler echocardiography (2DE). For comparison with 3DE A(LVOT), the SAM-septal distance was determined by 2DE. RESULTS: Real-time 3DE provided unique information about the dynamic SAM-septal relation during systole, with A(LVOT) ranging from 0.6 to 5.2 cm(2) (mean: 2.2 +/- 1.4 cm(2)). Maximal velocity (v) correlated inversely with A(LVOT) (v = 496 A(LVOT)(-0.80), r = -0.95, p < 0.001), but the exponent (-0.80) was significantly different from -1.0 (95% confidence interval: -0.67 to -0.92), indicating a significant impact of small A(LVOT) on the peak LVOT flow rate. By comparison, the best correlation between velocity and 2DE SAM-septal distance was significantly (p < 0.01) poorer at -0.83, indicating the superiority of 3DE for assessing A(LVOT). CONCLUSIONS: Three-dimensional echocardiography-measured A(LVOT) provides an assessment of HCM geometry that is superior to 2DE methods. These data indicate that the peak LVOT flow rate appears to be significantly decreased by reduced A(LVOT). Real-time 3DE is a potentially valuable clinical tool for assessing patients with HCM.

  8. Real-time three-dimensional color Doppler echocardiography for characterizing the spatial velocity distribution and quantifying the peak flow rate in the left ventricular outflow tract

    NASA Technical Reports Server (NTRS)

    Tsujino, H.; Jones, M.; Shiota, T.; Qin, J. X.; Greenberg, N. L.; Cardon, L. A.; Morehead, A. J.; Zetts, A. D.; Travaglini, A.; Bauer, F.; Panza, J. A.; Thomas, J. D.

    2001-01-01

    Quantification of flow with pulsed-wave Doppler assumes a "flat" velocity profile in the left ventricular outflow tract (LVOT), which observation refutes. Recent development of real-time, three-dimensional (3-D) color Doppler allows one to obtain an entire cross-sectional velocity distribution of the LVOT, which is not possible using conventional 2-D echo. In an animal experiment, the cross-sectional color Doppler images of the LVOT at peak systole were derived and digitally transferred to a computer to visualize and quantify spatial velocity distributions and peak flow rates. Markedly skewed profiles, with higher velocities toward the septum, were consistently observed. Reference peak flow rates by electromagnetic flow meter correlated well with 3-D peak flow rates (r = 0.94), but with an anticipated underestimation. Real-time 3-D color Doppler echocardiography was capable of determining cross-sectional velocity distributions and peak flow rates, demonstrating the utility of this new method for better understanding and quantifying blood flow phenomena.

  9. Objective evaluation of changes in left ventricular and atrial volumes during parabolic flight using real-time three-dimensional echocardiography.

    PubMed

    Caiani, E G; Sugeng, L; Weinert, L; Capderou, A; Lang, R M; Vaïda, P

    2006-08-01

    We tested the feasibility of real-time three-dimensional (3D) echocardiographic (RT3DE) imaging to measure left heart volumes at different gravity during parabolic flight and studied the effects of lower body negative pressure (LBNP) as a countermeasure. Weightlessness-related changes in cardiac function have been previously studied during spaceflights using both 2D and 3D echocardiography. Several technical factors, such as inability to provide real-time analysis and the need for laborious endocardial definition, have limited its usefulness. RT3DE imaging overcomes these limitations by acquiring real-time pyramidal data sets encompassing the entire ventricle. RT3DE data sets were obtained (Philips 7500, X3) during breath hold in 16 unmedicated normal subjects in upright standing position at different gravity phases during parabolic flight (normogravity, 1 Gz; hypergravity, 1.8 Gz; microgravity, 0 Gz), with LBNP applied (-50 mmHg) at 0 Gz in selected parabolas. RT3DE imaging during parabolic flight was feasible in 14 of 16 subjects. Data were analyzed (Tomtec) to quantify left ventricular (LV) and atrial (LA) volumes at end diastole and end systole, which significantly decreased at 1.8 Gz and increased at 0 Gz. While ejection fraction did not change with gravity, stroke volume was reduced by 16% at 1.8 Gz and increased by 20% at 0 Gz, but it was not significantly different from 1 Gz values with LBNP. RT3DE during parabolic flight is feasible and provides the basis for accurate quantification of LV and LA volume changes with gravity. As LBNP counteracted the increase of LV and LA volumes caused by changes in venous return, it may be effectively used for preventing cardiac dilatation during 0 Gz.

  10. Nanoelectronic three-dimensional (3D) nanotip sensing array for real-time, sensitive, label-free sequence specific detection of nucleic acids

    PubMed Central

    Yang, Lu; koochak, Zahra; Harris, James S.; Davis, Ronald W.

    2016-01-01

    The improvements in our ability to sequence and genotype DNA have opened up numerous avenues in the understanding of human biology and medicine with various applications, especially in medical diagnostics. But the realization of a label free, real time, high-throughput and low cost biosensing platforms to detect molecular interactions with a high level of sensitivity has been yet stunted due to two factors: one, slow binding kinetics caused by the lack of probe molecules on the sensors and two, limited mass transport due to the planar structure (two-dimensional) of the current biosensors. Here we present a novel three-dimensional (3D), highly sensitive, real-time, inexpensive and label-free nanotip array as a rapid and direct platform to sequence-specific DNA screening. Our nanotip sensors are designed to have a nano sized thin film as their sensing area (~ 20 nm), sandwiched between two sensing electrodes. The tip is then conjugated to a DNA oligonucleotide complementary to the sequence of interest, which is electrochemically detected in real-time via impedance changes upon the formation of a double-stranded helix at the sensor interface. This 3D configuration is specifically designed to improve the biomolecular hit rate and the detection speed. We demonstrate that our nanotip array effectively detects oligonucleotides in a sequence-specific and highly sensitive manner, yielding concentration-dependent impedance change measurements with a target concentration as low as 10 pM and discrimination against even a single mismatch. Notably, our nanotip sensors achieve this accurate, sensitive detection without relying on signal indicators or enhancing molecules like fluorophores. It can also easily be scaled for highly multiplxed detection with up to 5000 sensors/square centimeter, and integrated into microfluidic devices. The versatile, rapid, and sensitive performance of the nanotip array makes it an excellent candidate for point-of-care diagnostics, and high

  11. Two-dimensional tissue tracking: a novel echocardiographic technique to measure left atrial volume: comparison with biplane area length method and real time three-dimensional echocardiography.

    PubMed

    Li, Shi-Yan; Zhang, Li; Zhao, Bo-Wen; Yu, Chan; Xu, Li-Long; Li, Peng; Xu, Ke; Pan, Mei; Wang, Bei

    2014-07-01

    Enlargement of the left atrium is an independent predictor of adverse cardiovascular outcomes, and an accurate, convenient imaging modality is necessary for clinical practice. The objectives of this study were to evaluate the feasibility of a novel imaging technique, two-dimensional tissue tracking (2DTT), for assessment of left atrial (LA) volume and function and to compare its correlation and agreement with biplane area length (AL) method and real time three-dimensional echocardiography (RT3DE). A total of 105 patients prospectively underwent 2DTT, AL and RT3DE. The LA volume index (LAVI) and emptying fraction were measured. In addition, intra- and inter-observer agreement were calculated by using the intraclass correlation coefficient. There were no significant differences in LAVI and emptying fraction measured by 2DTT in comparison with those made by AL or RT3DE, furthermore Bland-Altman analysis showed that 2DTT had significantly better agreement for LAVI and emptying fraction with AL and RT3DE. 2DTT also exhibited smaller intra- and inter-observer variability as compared with AL or RT3DE. Furthermore, the time to measure LA volume and acquire time-volume curve was significantly less by 2DTT than that by RT3DE (U = 49.00, P < 0.001). These observations suggest that the 2DTT could provide valuable information which is consistent with the standard AL and RT3DE measurements for LAVI and function with potentially lower intra- and inter-observer variability.

  12. Bootstrapping Critical Ising Model on Three Dimensional Real Projective Space.

    PubMed

    Nakayama, Yu

    2016-04-01

    Given conformal data on a flat Euclidean space, we use crosscap conformal bootstrap equations to numerically solve the Lee-Yang model as well as the critical Ising model on a three dimensional real projective space. We check the rapid convergence of our bootstrap program in two dimensions from the exact solutions available. Based on the comparison, we estimate that our systematic error on the numerically solved one-point functions of the critical Ising model on a three dimensional real projective space is less than 1%. Our method opens up a novel way to solve conformal field theories on nontrivial geometries.

  13. High precision in Raman frequency achieved using real-time calibration with a neon emission line: application to three-dimensional stress mapping observations.

    PubMed

    Odake, Shoko; Fukura, Satoshi; Kagi, Hiroyuki

    2008-10-01

    A three-dimensional (3D) Raman mapping system with a real-time calibration function was developed for detecting stress distributions in solid materials from subtle frequency shifts in Raman spectra. An atomic emission line of neon at 918.3 cm(-1) when excited at 514.5 nm was used as a wavenumber standard. An emission spectrum of neon and a Raman spectrum from a sample were introduced into a single polychromator using a bifurcated optical fiber. These two spectra were recorded simultaneously on a charge-coupled device (CCD) detector using double-track mode. Energy deviation induced by the fluctuation of laboratory temperature, etc., was removed effectively using the neon emission line. High stability during long measurements was achieved. By applying curve fitting, positions of the Raman line were determined with precision of about 0.05 cm(-1). The present system was applied to measurements of residual pressure around mineral inclusions in a natural diamond: 3D stress mapping was achieved. PMID:18926016

  14. Incremental value of live/real time three-dimensional transesophageal echocardiography over the two-dimensional technique in the assessment of a tuberculoma involving the left atrium and appendage.

    PubMed

    Kemaloğlu Öz, Tuğba; Elsayed, Mahmoud; Nanda, Navin C; Kalenderoğlu, Koray; Akyüz, Şükrü; Atasoy, Işıl; Ösken, Altuğ; Onuk, Tolga; Eren, Mehmet

    2016-09-01

    Intracardiac tuberculomas are extremely rare, and cardiac involvement in tuberculosis accounts for only 0.5% of extrapulmonary tuberculosis. We report for the first time incremental value of live/real time three-dimensional transesophageal echocardiography over two-dimensional transesophageal echocardiography in the assessment of a tuberculoma involving the left atrium and left atrial appendage.

  15. Validation of real-time three-dimensional echocardiography for quantifying left ventricular volumes in the presence of a left ventricular aneurysm: in vitro and in vivo studies

    NASA Technical Reports Server (NTRS)

    Qin, J. X.; Jones, M.; Shiota, T.; Greenberg, N. L.; Tsujino, H.; Firstenberg, M. S.; Gupta, P. C.; Zetts, A. D.; Xu, Y.; Ping Sun, J.; Cardon, L. A.; Odabashian, J. A.; Flamm, S. D.; White, R. D.; Panza, J. A.; Thomas, J. D.

    2000-01-01

    OBJECTIVES: To validate the accuracy of real-time three-dimensional echocardiography (RT3DE) for quantifying aneurysmal left ventricular (LV) volumes. BACKGROUND: Conventional two-dimensional echocardiography (2DE) has limitations when applied for quantification of LV volumes in patients with LV aneurysms. METHODS: Seven aneurysmal balloons, 15 sheep (5 with chronic LV aneurysms and 10 without LV aneurysms) during 60 different hemodynamic conditions and 29 patients (13 with chronic LV aneurysms and 16 with normal LV) underwent RT3DE and 2DE. Electromagnetic flow meters and magnetic resonance imaging (MRI) served as reference standards in the animals and in the patients, respectively. Rotated apical six-plane method with multiplanar Simpson's rule and apical biplane Simpson's rule were used to determine LV volumes by RT3DE and 2DE, respectively. RESULTS: Both RT3DE and 2DE correlated well with actual volumes for aneurysmal balloons. However, a significantly smaller mean difference (MD) was found between RT3DE and actual volumes (-7 ml for RT3DE vs. 22 ml for 2DE, p = 0.0002). Excellent correlation and agreement between RT3DE and electromagnetic flow meters for LV stroke volumes for animals with aneurysms were observed, while 2DE showed lesser correlation and agreement (r = 0.97, MD = -1.0 ml vs. r = 0.76, MD = 4.4 ml). In patients with LV aneurysms, better correlation and agreement between RT3DE and MRI for LV volumes were obtained (r = 0.99, MD = -28 ml) than between 2DE and MRI (r = 0.91, MD = -49 ml). CONCLUSIONS: For geometrically asymmetric LVs associated with ventricular aneurysms, RT3DE can accurately quantify LV volumes.

  16. Methodology for geographical data evolution: three-dimensional particle-based real-time snow simulation with remote-sensing data

    NASA Astrophysics Data System (ADS)

    Tan, Jian; Fan, Xiangtao; Ren, Yingchao

    2014-01-01

    Even if current remote-sensing technology provides more spatial information, remote-sensing data with discontinuous spatial and temporal resolutions are still not adequate. To compensate for the missing data of remote sensing, we create a methodology for geographical data evolution from a snow simulation. Numerical algorithms based on snow simulation and environmental phenomenon interaction algorithms are presented to evolve remote-sensing data in a virtual environment. Specifically, the methodology involves the establishment of a suitable three-dimensional data model and the discrete numerical expressions of geological or geographical phenomena. The modeling solution of environmental phenomena reactions is based on remote-sensing data. This computational simulation does not merely generate new data and spatial resolutions at a given time, but it offers multiscale environmental characteristics of the Earth and presents reference for its future scene.

  17. Real-time three-dimensional color doppler evaluation of the flow convergence zone for quantification of mitral regurgitation: Validation experimental animal study and initial clinical experience

    NASA Technical Reports Server (NTRS)

    Sitges, Marta; Jones, Michael; Shiota, Takahiro; Qin, Jian Xin; Tsujino, Hiroyuki; Bauer, Fabrice; Kim, Yong Jin; Agler, Deborah A.; Cardon, Lisa A.; Zetts, Arthur D.; Panza, Julio A.; Thomas, James D.

    2003-01-01

    BACKGROUND: Pitfalls of the flow convergence (FC) method, including 2-dimensional imaging of the 3-dimensional (3D) geometry of the FC surface, can lead to erroneous quantification of mitral regurgitation (MR). This limitation may be mitigated by the use of real-time 3D color Doppler echocardiography (CE). Our objective was to validate a real-time 3D navigation method for MR quantification. METHODS: In 12 sheep with surgically induced chronic MR, 37 different hemodynamic conditions were studied with real-time 3DCE. Using real-time 3D navigation, the radius of the largest hemispherical FC zone was located and measured. MR volume was quantified according to the FC method after observing the shape of FC in 3D space. Aortic and mitral electromagnetic flow probes and meters were balanced against each other to determine reference MR volume. As an initial clinical application study, 22 patients with chronic MR were also studied with this real-time 3DCE-FC method. Left ventricular (LV) outflow tract automated cardiac flow measurement (Toshiba Corp, Tokyo, Japan) and real-time 3D LV stroke volume were used to quantify the reference MR volume (MR volume = 3DLV stroke volume - automated cardiac flow measurement). RESULTS: In the sheep model, a good correlation and agreement was seen between MR volume by real-time 3DCE and electromagnetic (y = 0.77x + 1.48, r = 0.87, P <.001, delta = -0.91 +/- 2.65 mL). In patients, real-time 3DCE-derived MR volume also showed a good correlation and agreement with the reference method (y = 0.89x - 0.38, r = 0.93, P <.001, delta = -4.8 +/- 7.6 mL). CONCLUSIONS: real-time 3DCE can capture the entire FC image, permitting geometrical recognition of the FC zone geometry and reliable MR quantification.

  18. Time of Closest Approach in Three-Dimensional Airspace

    NASA Technical Reports Server (NTRS)

    Munoz, Cesar A.; Narkawicz, Anthony J.

    2010-01-01

    In air traffic management, the aircraft separation requirement is defined by a minimum horizontal distance and a minimum vertical distance that the aircraft have to maintain. Since this requirement defines a cylinder around each aircraft rather than a sphere, the three-dimensional Euclidean distance does not provide an appropriate basis for the definition of time of closest approach. For instance, conflicting aircraft are not necessarily in loss of separation at the time of closest three-dimensional Euclidean distance. This paper proposes a definition of time of closest approach that characterizes conflicts in a three-dimensional airspace. The proposed time is defined as the time that minimizes a distance metric called cylindrical norm. An algorithm that computes the time of closest approach between two aircraft is provided and the formal verification of its main properties is reported.

  19. Real-time bronchoscope three-dimensional motion estimation using multiple sensor-driven alignment of CT images and electromagnetic measurements.

    PubMed

    Luo, Xiongbiao; Mori, Kensaku

    2014-09-01

    Bronchoscope three-dimensional motion estimation plays a key role in developing bronchoscopic navigation systems. Currently external tracking devices, particularly electromagnetic trackers with electromagnetic sensors, are increasingly introduced to navigate surgical tools in pre-clinical images. An unavoidable problem, which is to align the electromagnetic tracker to pre-clinical images, must be solved before navigation. This paper proposes a multiple sensor-driven registration method to establish this alignment without using any anatomical fiducials. Although current fiducially free registration methods work well, they limit to the initialization of optimization and manipulating the bronchoscope along the bronchial centerlines, which could be failed easily during clinical interventions. To address these limitations, we utilize measurements of multiple electromagnetic sensors to calculate bronchoscope geometric center positions that are usually closer to the bronchial centerlines than the sensor itself measured positions. We validated our method on a bronchial phantom. The experimental results demonstrate that our idea of using multiple sensors to determine bronchoscope geometric center positions for fiducial-free registration was very effective. Compared to currently available methods in bronchoscope three-dimensional motion estimation, our method reduced fiducial alignment error from at least 6.79 to 4.68-5.26 mm and significantly improved motion estimation or tracking accuracy from at least 5.42 to 3.78-4.53 mm.

  20. Importance of mitral valve repair associated with left ventricular reconstruction for patients with ischemic cardiomyopathy: a real-time three-dimensional echocardiographic study

    NASA Technical Reports Server (NTRS)

    Qin, Jian Xin; Shiota, Takahiro; McCarthy, Patrick M.; Asher, Craig R.; Hail, Melanie; Agler, Deborah A.; Popovic, Zoran B.; Greenberg, Neil L.; Smedira, Nicholas G.; Starling, Randall C.; Young, James B.; Thomas, James D.

    2003-01-01

    BACKGROUND: Left ventricular (LV) reconstruction surgery leads to early improvement in LV function in ischemic cardiomyopathy (ICM) patients. This study was designed to evaluate the impact of mitral valve (MV) repair associated with LV reconstruction on LV function 1-year after surgery in ICM patients assessed by real-time 3-dimensional echocardiography (3DE). METHODS AND RESULTS: Sixty ICM patients who underwent the combination surgery (LV reconstruction in 60, MV repair in 30, and revascularization in 52 patients) were studied. Real-time 3DE was performed and LV volumes were obtained at baseline, discharge, 6-month and >or=12-month follow-up. Reduction in end-diastolic volumes (EDV) by 29% and in end-systolic volumes by 38% were demonstrated immediately after surgery and remained at subsequent follow-up (P<0.0001). The LV ejection fraction significantly increased by about 10% at discharge and was maintained >or=12-month (P<0.0001). Although the LV volumes were significantly larger in patients with MV repair before surgery (EDV, 235+/-87 mL versus 193+/-67 mL, P<0.05), they were similar to LV volumes of the patients without MV repair at subsequent follow-ups. However, the EDV increased from 139+/-24 mL to 227+/-79 mL (P<0.01) in 7 patients with recurrent mitral regurgitation (MR). Improvement in New York Heart Association functional class occurred in 81% patients during late follow-up. CONCLUSIONS: Real-time 3DE demonstrates that LV reconstruction provides significant reduction in LV volumes and improvement in LV function which is sustained throughout the 1-year follow-up with 84% cardiac event free survival. If successful, MV repair may prevent LV redilation, while recurrent MR is associated with increased LV volumes.

  1. Camera-based three-dimensional real-time particle tracking at kHz rates and Ångström accuracy

    PubMed Central

    Daldrop, Peter; Joo, Sihwa; Otto, Oliver; Keyser, Ulrich F.; Seidel, Ralf

    2014-01-01

    Optical and magnetic tweezers are widely employed to probe the mechanics and activity of individual biomolecular complexes. They rely on micrometer-sized particles to detect molecular conformational changes from the particle position. Real-time particle tracking with Ångström accuracy has so far been only achieved using laser detection through photodiodes. Here we demonstrate that camera-based imaging can provide a similar performance for all three dimensions. Particle imaging at kHz rates is combined with real-time data processing being accelerated by a graphics processing unit. For particles that are fixed in the sample cell we can detect 3 Å sized steps that are introduced by cell translations at rates of 10 Hz, while for DNA-tethered particles 5 Å steps at 1 Hz can be resolved. Moreover, 20 particles can be tracked in parallel with comparable accuracy. Our approach provides a simple and robust way for high-resolution tweezers experiments using multiple particles at a time. PMID:25565216

  2. Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time

    PubMed Central

    Deán-Ben, Xosé; Fehm, Thomas Felix; Razansky, Daniel

    2014-01-01

    The exclusive combination of high optical contrast and excellent spatial resolution makes optoacoustics (photoacoustics) ideal for simultaneously attaining anatomical, functional and molecular contrast in deep optically opaque tissues. While enormous potential has been recently demonstrated in the application of optoacoustics for small animal research, vast efforts have also been undertaken in translating this imaging technology into clinical practice. We present here a newly developed optoacoustic tomography approach capable of delivering high resolution and spectrally enriched volumetric images of tissue morphology and function in real time. A detailed description of the experimental protocol for operating with the imaging system in both hand-held and stationary modes is provided and showcased for different potential scenarios involving functional and molecular studies in murine models and humans. The possibility for real time visualization in three dimensions along with the versatile handheld design of the imaging probe make the newly developed approach unique among the pantheon of imaging modalities used in today’s preclinical research and clinical practice. PMID:25408083

  3. Development of three-dimensional patient face model that enables real-time collision detection and cutting operation for a dental simulator.

    PubMed

    Yamaguchi, Satoshi; Yamada, Yuya; Yoshida, Yoshinori; Noborio, Hiroshi; Imazato, Satoshi

    2012-01-01

    The virtual reality (VR) simulator is a useful tool to develop dental hand skill. However, VR simulations with reactions of patients have limited computational time to reproduce a face model. Our aim was to develop a patient face model that enables real-time collision detection and cutting operation by using stereolithography (STL) and deterministic finite automaton (DFA) data files. We evaluated dependence of computational cost and constructed the patient face model using the optimum condition for combining STL and DFA data files, and assessed the computational costs for operation in do-nothing, collision, cutting, and combination of collision and cutting. The face model was successfully constructed with low computational costs of 11.3, 18.3, 30.3, and 33.5 ms for do-nothing, collision, cutting, and collision and cutting, respectively. The patient face model could be useful for developing dental hand skill with VR. PMID:23207214

  4. Evaluation of a real-time hybrid three-dimensional echo and X-ray imaging system for guidance of cardiac catheterisation procedures.

    PubMed

    Housden, R J; Arujuna, A; Ma, Y; Nijhof, N; Gijsbers, G; Bullens, R; O'Neill, M; Cooklin, M; Rinaldi, C A; Gill, J; Kapetanakis, S; Hancock, J; Thomas, M; Razavi, R; Rhode, K S

    2012-01-01

    Minimally invasive cardiac surgery is made possible by image guidance technology. X-ray fluoroscopy provides high contrast images of catheters and devices, whereas 3D ultrasound is better for visualising cardiac anatomy. We present a system in which the two modalities are combined, with a trans-esophageal echo volume registered to and overlaid on an X-ray projection image in real-time. We evaluate the accuracy of the system in terms of both temporal synchronisation errors and overlay registration errors. The temporal synchronisation error was found to be 10% of the typical cardiac cycle length. In 11 clinical data sets, we found an average alignment error of 2.9 mm. We conclude that the accuracy result is very encouraging and sufficient for guiding many types of cardiac interventions. The combined information is clinically useful for placing the echo image in a familiar coordinate system and for more easily identifying catheters in the echo volume.

  5. Real time three-dimensional echocardiography for quantification of ventricular volumes, mass, and function in children with congenital and acquired heart diseases.

    PubMed

    Balluz, Rula; Liu, Liwen; Zhou, Xiaodong; Ge, Shuping

    2013-04-01

    Quantitative measurement of left ventricular (LV) volumes, mass, and function is one of the most common and important indications for echocardiography. These measurements are among the most powerful tools for diagnosis and prognosis of congenital and acquired heart diseases and for assessment of medical, percutaneous, and surgical interventions. Awareness is also growing of the importance of right ventricular (RV) volume, mass, and function in many cardiopulmonary diseases. Furthermore, there are challenges and opportunities to measure the volume, mass, and function of complex chambers such as the left atrium, right atrium, and the univentricular heart. As echocardiography continues to be the imaging modality of choice for these measurements, the strengths and limitations of M-mode, two-dimensional (2D), and recently three-dimensional (3D) echocardiographic (3DE) methodologies for accurate and reproducible measurement of these indices have been extensively investigated for congenital and acquired heart diseases. Evidence suggests that 3DE provides improved accuracy and reproducibility over 2D methods for measurement of LV volume and function calculation in adults and in children. Data have accumulated on the utility of 3DE for measuring chamber volumes and function for the RV and for the single ventricle, which may become more widely used in clinical and research arenas in the future. Finally, new advanced modes of analysis such as 3D strain and synchrony analysis by 3DE are promising methodologies that warrant further investigation.

  6. Time-Domain Simulation of Three Dimensional Quantum Wires.

    PubMed

    Sullivan, Dennis M; Mossman, Sean; Kuzyk, Mark G

    2016-01-01

    A method is presented to calculate the eigenenergies and eigenfunctions of quantum wires. This is a true three-dimensional method based on a direct implementation of the time-dependent Schrödinger equation. It makes no approximations to the Schrödinger equation other than the finite-difference approximation of the space and time derivatives. The accuracy of our method is tested by comparing it to analytical results in a cylindrical wire. PMID:27124603

  7. Time-Domain Simulation of Three Dimensional Quantum Wires

    PubMed Central

    Mossman, Sean; Kuzyk, Mark G.

    2016-01-01

    A method is presented to calculate the eigenenergies and eigenfunctions of quantum wires. This is a true three-dimensional method based on a direct implementation of the time-dependent Schrödinger equation. It makes no approximations to the Schrödinger equation other than the finite-difference approximation of the space and time derivatives. The accuracy of our method is tested by comparing it to analytical results in a cylindrical wire. PMID:27124603

  8. Simulation of intraoperative visualization of cardiac structures and study of dynamic surgical anatomy with real-time three-dimensional echocardiography.

    PubMed

    Schwartz, S L; Cao, Q L; Azevedo, J; Pandian, N G

    1994-03-01

    Most prior efforts of 3-dimensional (3-D) reconstruction of echocardiographic images have focused on quantitation of ventricular size and function. The resulting images have been displayed in the wire mesh format. Recently, a method for 3-D transesophageal echocardiography using a computer-controlled probe that acquires parallel tomographic slices has been described. This technique provides dynamic 3-D volume-rendered images of the heart. This study was designed to determine if surgical visualization of intracardiac anatomy could be simulated using this imaging system. Data acquired from 8 patients with congenital and acquired heart disease were analyzed. Real-time 3-D images of the cardiac chambers and valves were obtained. Images of the cardiac pathology including fibrocalcific nodules on the aortic valve, mitral valve endocarditis, rheumatic mitral stenosis, and an ostium secundum atrial septal defect were displayed in 3 dimensions that simulated surgical exposure of these structures. These 3-D representations of cardiac anatomy were in some ways superior to standard intraoperative visualization in that they demonstrated the heart as a dynamic structure, as opposed to the empty, nonbeating heart observed while on cardiopulmonary bypass. In conclusion, 3-D images of cardiac structures as seen by the surgeon intraoperatively can be provided using a computer-driven tomographic transesophageal echocardiographic probe. This imaging system can be potentially useful in the planning and evaluation of cardiac surgery. Technical improvements such as 3-D representation of flow jets, the ability to manipulate images to simulate cardiac surgery, and on-line reconstruction can make this a powerful tool in the future.

  9. Geometric differences of the mitral apparatus between ischemic and dilated cardiomyopathy with significant mitral regurgitation: real-time three-dimensional echocardiography study

    NASA Technical Reports Server (NTRS)

    Kwan, Jun; Shiota, Takahiro; Agler, Deborah A.; Popovic, Zoran B.; Qin, Jian Xin; Gillinov, Marc A.; Stewart, William J.; Cosgrove, Delos M.; McCarthy, Patrick M.; Thomas, James D.

    2003-01-01

    BACKGROUND: This study was conducted to elucidate the geometric differences of the mitral apparatus in patients with significant mitral regurgitation caused by ischemic cardiomyopathy (ICM-MR) and by idiopathic dilated cardiomyopathy (DCM-MR) by use of real-time 3D echocardiography (RT3DE). METHODS AND RESULTS: Twenty-six patients with ICM-MR caused by posterior infarction, 18 patients with DCM-MR, and 8 control subjects were studied. With the 3D software, commissure-commissure plane and 3 perpendicular anteroposterior (AP) planes were generated for imaging the medial, central, and lateral sides of the mitral valve (MV) during mid systole. In 3 AP planes, the angles between the annular plane and each leaflet (anterior, Aalpha; posterior, Palpha) were measured. In ICM-MR, Aalpha measured in the medial and central planes was significantly larger than that in the lateral plane (39+/-5 degrees, 34+/-6 degrees, and 27+/-5 degrees, respectively; P<0.01), whereas Palpha showed no significant difference in any of the 3 AP planes (61+/-7 degrees, 57+/-7 degrees, and 56+/-7 degrees, P>0.05). In DCM-MR, both Aalpha (38+/-8 degrees, 37+/-9 degrees, and 36+/-7 degrees, P>0.05) and Palpha (59+/-6 degrees, 58+/-5 degrees, and 57+/-6 degrees, P>0.05) revealed no significant differences in the 3 planes. CONCLUSIONS: The pattern of MV deformation from the medial to the lateral side was asymmetrical in ICM-MR, whereas it was symmetrical in DCM-MR. RT3DE is a helpful tool for differentiating the geometry of the mitral apparatus between these 2 different types of functional mitral regurgitation.

  10. Incremental Value of Live/Real Time Three-Dimensional over Two-Dimensional Transesophageal Echocardiography in the Assessment of Atrial Septal Pouch.

    PubMed

    Elsayed, Mahmoud; Hsiung, Ming C; Meggo-Quiroz, L David; Elguindy, Mostafa; Uygur, Begum; Tandon, Rohit; Guvenc, Tolga; Keser, Nurgul; Vural, Mustafa G; Bulur, Serkan; Chahwala, Jugal R; Abtahi, Firoozeh; Nanda, Navin C

    2015-12-01

    An atrial septal pouch (ASP) results from partial fusion of the septum primum and the septum secundum, and depending on the site of fusion, the pouch can be left-sided (LASP) or right-sided (RASP). LASPs have been described in association with thrombi found in patients admitted with acute strokes, raising awareness of its potential cardioembolic role, especially in those with no other clearly identifiable embolic source. We retrospectively studied 39 patients in whom the presence of an ASP had been identified by three-dimensional transesophageal echocardiography (3DTEE) and who had a two-dimensional transesophageal echocardiogram (2DTEE) performed during the same clinical encounter. The incremental value provided by 3DTEE over 2DTEE included the detection of six ASPs not found by 2DTEE; the detection of two ASPs in the same subject (in four patients) not identified by 2DTEE; larger ASP measurements of length and height in over 80% of the cases; and measurement of the ASP width (elevational axis) for the calculation of the area of the ASP opening, because of its unique capability to view the pouch en face. In addition, the volume of ASP and of the echogenic masses contained in the ASP (four of 39 patients) could be calculated by 3DTEE, which is a superior parameter of size characterization when compared to individual dimensions. One of these patients who presented with ischemic stroke diagnosed by magnetic resonance imaging had a large (>2 cm) mass in a LASP, with echolucencies similar to those seen in thrombi and associated with clot lysis and resolution. This mass completely disappeared on anticoagulant therapy lending credence that it was most likely a thrombus. There was no history of stroke or any other type of embolic event in the other three patients with masses in ASP. In conclusion, this retrospective study highlights the incremental value of 3DTEE over 2DTEE in the comprehensive assessment and characterization of ASPs, which can aid in the clarification of

  11. Three-Dimensional Rotation, Twist and Torsion Analyses Using Real-Time 3D Speckle Tracking Imaging: Feasibility, Reproducibility, and Normal Ranges in Pediatric Population

    PubMed Central

    Han, Wei; Gao, Jun; He, Lin; Yang, Yali; Yin, Ping; Xie, Mingxing; Ge, Shuping

    2016-01-01

    Background and Objective The specific aim of this study was to evaluate the feasibility, reproducibility and maturational changes of LV rotation, twist and torsion variables by real-time 3D speckle-tracking echocardiography (RT3DSTE) in children. Methods A prospective study was conducted in 347 consecutive healthy subjects (181 males/156 females, mean age 7.12 ± 5.3 years, and range from birth to 18-years) using RT 3D echocardiography (3DE). The LV rotation, twist and torsion measurements were made off-line using TomTec software. Manual landmark selection and endocardial border editing were performed in 3 planes (apical “2”-, “4”-, and “3”- chamber views) and semi-automated tracking yielded LV rotation, twist and torsion measurements. LV rotation, twist and torsion analysis by RT 3DSTE were feasible in 307 out of 347 subjects (88.5%). Results There was no correlation between rotation or twist and age, height, weight, BSA or heart rate, respectively. However, there was statistically significant, but very modest correlation between LV torsion and age (R2 = 0.036, P< 0.001). The normal ranges were defined for rotation and twist in this cohort, and for torsion for each age group. The intra-observer and inter-observer variabilities for apical and basal rotation, twist and torsion ranged from 7.3% ± 3.8% to 12.3% ± 8.8% and from 8.8% ± 4.6% to 15.7% ± 10.1%, respectively. Conclusions We conclude that analysis of LV rotation, twist and torsion by this new RT3D STE is feasible and reproducible in pediatric population. There is no maturational change in rotation and twist, but torsion decreases with age in this cohort. Further refinement is warranted to validate the utility of this new methodology in more sensitive and quantitative evaluation of congenital and acquired heart diseases in children. PMID:27427968

  12. Single-pixel three-dimensional imaging with time-based depth resolution

    NASA Astrophysics Data System (ADS)

    Sun, Ming-Jie; Edgar, Matthew P.; Gibson, Graham M.; Sun, Baoqing; Radwell, Neal; Lamb, Robert; Padgett, Miles J.

    2016-07-01

    Time-of-flight three-dimensional imaging is an important tool for applications such as object recognition and remote sensing. Conventional time-of-flight three-dimensional imaging systems frequently use a raster scanned laser to measure the range of each pixel in the scene sequentially. Here we show a modified time-of-flight three-dimensional imaging system, which can use compressed sensing techniques to reduce acquisition times, whilst distributing the optical illumination over the full field of view. Our system is based on a single-pixel camera using short-pulsed structured illumination and a high-speed photodiode, and is capable of reconstructing 128 × 128-pixel resolution three-dimensional scenes to an accuracy of ~3 mm at a range of ~5 m. Furthermore, by using a compressive sampling strategy, we demonstrate continuous real-time three-dimensional video with a frame-rate up to 12 Hz. The simplicity of the system hardware could enable low-cost three-dimensional imaging devices for precision ranging at wavelengths beyond the visible spectrum.

  13. Real-time two- and three-dimensional imaging of monocyte motility and navigation on planar surfaces and in collagen matrices: roles of Rho

    PubMed Central

    Bzymek, Robert; Horsthemke, Markus; Isfort, Katrin; Mohr, Simon; Tjaden, Kerstin; Müller-Tidow, Carsten; Thomann, Marlies; Schwerdtle, Tanja; Bähler, Martin; Schwab, Albrecht; Hanley, Peter J.

    2016-01-01

    We recently found that macrophages from RhoA/RhoB double knockout mice had increased motility of the cell body, but severely impaired retraction of the tail and membrane extensions, whereas RhoA- or RhoB-deficient cells exhibited mild phenotypes. Here we extended this work and investigated the roles of Rho signaling in primary human blood monocytes migrating in chemotactic gradients and in various settings. Monocyte velocity, but not chemotactic navigation, was modestly dependent on Rho-ROCK-myosin II signaling on a 2D substrate or in a loose collagen type I matrix. Viewed by time-lapse epi-fluorescence microscopy, monocytes appeared to flutter rather than crawl, such that the 3D surface topology of individual cells was difficult to predict. Spinning disk confocal microscopy and 3D reconstruction revealed that cells move on planar surfaces and in a loose collagen matrix using prominent, curved planar protrusions, which are rapidly remodeled and reoriented, as well as resorbed. In a dense collagen type I matrix, there is insufficient space for this mode and cells adopt a highly Rho-dependent, lobular mode of motility. Thus, in addition to its role in tail retraction on 2D surfaces, Rho is critical for movement in confined spaces, but is largely redundant for motility and chemotaxis in loose matrices. PMID:27122054

  14. Deployment of a three-dimensional array of Micro-Pocket Fission Detector triads (MPFD3) for real-time, in-core neutron flux measurements in the Kansas State University TRIGA Mark-II Nuclear Reactor

    NASA Astrophysics Data System (ADS)

    Ohmes, Martin Francis

    A Micro-Pocket Fission Detector (MPFD) is a miniaturized type of fission chamber developed for use inside a nuclear reactor. Their unique design allows them to be located between or even inside fuel pins while being built from materials which give them an operational lifetime comparable to or exceeding the life of the fuel. While other types of neutron detectors have been made for use inside a nuclear reactor, the MPFD is the first neutron detector which can survive sustained use inside a nuclear reactor while providing a real-time measurement of the neutron flux. This dissertation covers the deployment of MPFDs as a large three-dimensional array inside the Kansas State University TRIGA Mark-II Nuclear Reactor for real-time neutron flux measurements. This entails advancements in the design, construction, and packaging of the Micro-Pocket Fission Detector Triads with incorporated Thermocouple, or MPFD3-T. Specialized electronics and software also had to be designed and built in order to make a functional system capable of collecting real-time data from up to 60 MPFD3-Ts, or 180 individual MPFDs and 60 thermocouples. Design of the electronics required the development of detailed simulations and analysis for determining the theoretical response of the detectors and determination of their size. The results of this research shows that MPFDs can operate for extended times inside a nuclear reactor and can be utilized toward the use as distributed neutron detector arrays for advanced reactor control systems and power mapping. These functions are critical for continued gains in efficiency of nuclear power reactors while also improving safety through relatively inexpensive redundancy.

  15. Left ventricular layer function in hypertension assessed by myocardial strain rate using novel one-beat real-time three-dimensional speckle tracking echocardiography with high volume rates.

    PubMed

    Saeki, Maki; Sato, Noriaki; Kawasaki, Masanori; Tanaka, Ryuhei; Nagaya, Maki; Watanabe, Takatomo; Ono, Koji; Noda, Toshiyuki; Zile, Michael R; Minatoguchi, Shinya

    2015-08-01

    We recently developed novel software to measure phasic strain rate (SR) using automated one-beat real-time three-dimensional speckle tracking echocardiography (3D-STE) with high volume rates. We tested the hypothesis that left ventricular (LV) systolic function and relaxation analyzed by SR with the novel 3D-STE in hypertension (HTN) with hypertrophy may be impaired in the endocardium before there is LV systolic dysfunction. We measured LV longitudinal, radial and circumferential SR in patients with HTN (n=80, 69±7 years) and age-matched normotensive controls (n= 60, 69±10 years) using 3D-STE. HTN patients were divided into four groups according to LV geometry: normal, concentric remodeling, concentric hypertrophy and eccentric hypertrophy. We measured SR during systole as an index of systolic function, SR during isovolumic relaxation (IVR) as an index of relaxation and E/e' as an index of filling pressure. Endocardial SR during systole in HTN with concentric and eccentric hypertrophy decreased compared with that in controls despite no reduction in ejection fraction or epicardial SR. Endocardial radial SR during IVR decreased even in normal geometry, and it was further reduced in concentric remodeling and hypertrophy despite no reduction in epicardial SR. LV phasic SR assessed by 3D-STE with high volume rates is a useful index to detect early decreases in LV systolic function and to predict subclinical LV layer dysfunction in patients with HTN.

  16. Comparison of accuracy of aortic valve area assessment in aortic stenosis by real time three-dimensional echocardiography in biplane mode versus two-dimensional transthoracic and transesophageal echocardiography.

    PubMed

    Blot-Souletie, Nathalie; Hébrard, Aurélien; Acar, Philippe; Carrié, Didier; Puel, Jacques

    2007-11-01

    Our aim was to validate the clinical feasibility of assessment of the area of the aortic valve orifice (AVA) by real time three-dimensional echocardiography (RT3DE) in biplane mode by planimetry and to compare it with the echo-Doppler methods more commonly used to evaluate valvular aortic stenosis (AS).RT3DE in biplane mode is a novel technique that allows operators to visualize the aortic valve orifice anatomy in any desired plane orientation. Its usefulness and accuracy have not previously been established. Using this technique, we studied a series of patients with AS and compared the results with those obtained by two-dimensional transesophageal echocardiography (TEE) planimetry and two-dimensional transthoracic echocardiography using the continuity equation (TTE-CE). RT3DE planimetries in biplane mode were measured by two independent observers. Bland-Altman analysis was used to compare these two methods.Forty-one patients with AS were enrolled in the study (15 women, 26 men, mean age 73.5 +/- 8.2 years). RT3DE planimetry was feasible in 92.7%. Average AVA determined by TTE-CE was 0.76 +/- 0.20 cm, by TEE planimetry 0.73 +/- 0.1 cm, and by RT3DE planimetry 0.76 +/- 0.20 cm(2). The average differences in AVA were-0.001 +/- 0.254 cm(2) and 0.03 +/- 0.155 cm(2) (RT3DE/TEE). The correlation coefficient for AVA (RT3DE/TTE-CE) was 0.82 and for AVA (RT3DE/TEE) it was 0.94, P < 0.0001. No significant intra- and interobserver variability was observed. In conclusion, RT3DE in biplane mode provides a feasible and reproducible method for measuring the area of the aortic valve orifice in aortic stenosis.

  17. New techniques in television to provide research in three-dimensional real-time or near real-time imagery and reduced cost systems for teleconferencing and educational uses, part 1

    NASA Technical Reports Server (NTRS)

    Pao, Y. H.; Claspy, P.; Allen, J. E.; Merat, F.

    1979-01-01

    The results are presented of a continuing research and development program the objective of which is to develop a reduced bandwidth television system and a technique for television transmission of holograms. The result of the former is a variable frame rate television system, the operation of which was demonstrated for both black-and-white and color signals. This system employs a novel combination of the inexpensive mass storage capacity of a magnetic disc with the reliability of a digital system for time expansion and compression. Also reported are the results of a theoretical analysis and preliminary feasibility experiment of an innovative system for television transmission of holograms using relatively conventional TV equipment along with a phase modulated reference wave for production of the original interference pattern.

  18. Three-Dimensional Numerical Modeling of Initial Mixing of Thermal Discharges at Real-Life Configurations

    SciTech Connect

    Tang, Hansong; Paik, Joongcheol; Sotiropoulos, Fotis; Khangaonkar, Tarang P.

    2008-09-01

    A three-dimensional Reynolds-averaged Navier-Stokes (RANS) computational fluid dynamics (CFD) model is developed for simulating turbulent mixing in the near-field of thermal discharge at real-life geometrical configurations. The domain decomposition method with the multi-level embedded overset grids is employed to handle the complexity of real-life diffusers as well as to efficiently account for the large disparity of length scales arising from the relative size of the ambient river reach and the typical diffuser diameter.

  19. Three-dimensional time reversal communications in elastic media

    DOE PAGESBeta

    Anderson, Brian E.; Ulrich, Timothy J.; Le Bas, Pierre-Yves; Ten Cate, James A.

    2016-02-23

    Our letter presents a series of vibrational communication experiments, using time reversal, conducted on a set of cast iron pipes. Time reversal has been used to provide robust, private, and clean communications in many underwater acoustic applications. Also, the use of time reversal to communicate along sections of pipes and through a wall is demonstrated here in order to overcome the complications of dispersion and multiple scattering. These demonstrations utilize a single source transducer and a single sensor, a triaxial accelerometer, enabling multiple channels of simultaneous communication streams to a single location.

  20. Method for producing three-dimensional real image using radiographic perspective views of an object

    DOEpatents

    Ellingson, William A.; Read, Alvin A.

    1976-02-24

    A sequence of separate radiographs are made by indexing a radiation source along a known path relative to the object under study. Thus, each radiograph contains information from a different perspective. A holographically-recorded image is then made from each radiographic perspective by exact re-tracing of the rays through each radiographic perspective such that the re-tracing duplicates the geometry under which it was originally prepared. The holographically-stored images are simultaneously illuminated with the conjugate of the reference beam used in the original recordings. The result is the generation of a three-dimensional real image of the object such that a light-sensitive device can be moved to view the real image along any desired surface with the optical information in all other surfaces greatly suppressed.

  1. Numerical computation of multishocked, three-dimensional supersonic flow fields with real gas effects.

    NASA Technical Reports Server (NTRS)

    Kutler, P.; Reinhardt, W. A.; Warming, R. F.

    1972-01-01

    A computational procedure is presented which is capable of determining the supersonic flow field surrounding three-dimensional wing-body configurations such as a delta-wing space shuttle. The governing equations in conservation-law form are solved by a finite difference method using a second-order noncentered algorithm between the body and the outermost shock wave, which is treated as a sharp discontinuity. Secondary shocks which form between these boundaries are captured automatically, and the intersection of these shocks with the bow shock posed no difficulty. Resulting flow fields about typical blunt nose shuttle-like configurations at angle of attack are presented. The differences between perfect and real gas effects for high Mach number flows are shown.

  2. A three dimensional multigrid multiblock multistage time stepping scheme for the Navier-Stokes equations

    NASA Technical Reports Server (NTRS)

    Elmiligui, Alaa; Cannizzaro, Frank; Melson, N. D.

    1991-01-01

    A general multiblock method for the solution of the three-dimensional, unsteady, compressible, thin-layer Navier-Stokes equations has been developed. The convective and pressure terms are spatially discretized using Roe's flux differencing technique while the viscous terms are centrally differenced. An explicit Runge-Kutta method is used to advance the solution in time. Local time stepping, adaptive implicit residual smoothing, and the Full Approximation Storage (FAS) multigrid scheme are added to the explicit time stepping scheme to accelerate convergence to steady state. Results for three-dimensional test cases are presented and discussed.

  3. Hydrogeophysical exploration of three-dimensional salinity anomalies with the time-domain electromagnetic method (TDEM)

    NASA Astrophysics Data System (ADS)

    Bauer-Gottwein, Peter; Gondwe, Bibi N.; Christiansen, Lars; Herckenrath, Daan; Kgotlhang, Lesego; Zimmermann, Stephanie

    2010-01-01

    SummaryThe time-domain electromagnetic method (TDEM) is widely used in groundwater exploration and geological mapping applications. TDEM measures subsurface electrical conductivity, which is strongly correlated with groundwater salinity. TDEM offers a cheap and non-invasive option for mapping saltwater intrusion and groundwater salinization. Traditionally, TDEM data is interpreted using one-dimensional layered-earth models of the subsurface. However, most saltwater intrusion and groundwater salinization phenomena are characterized by three-dimensional anomalies. To fully exploit the information content of TDEM data in this context, three-dimensional modeling of the TDEM response is required. We present a finite-element solution for three-dimensional forward modeling of TDEM responses from arbitrary subsurface electrical conductivity distributions. The solution is benchmarked against standard layered-earth models and previously published three-dimensional forward TDEM modeling results. Concentration outputs from a groundwater flow and salinity transport model are converted to subsurface electrical conductivity using standard petrophysical relationships. TDEM responses over the resulting subsurface electrical conductivity distribution are generated using the three-dimensional TDEM forward model. The parameters of the hydrodynamic model are constrained by matching observed and simulated TDEM responses. As an application example, a field dataset of ground-based TDEM data from an island in the Okavango Delta is presented. Evaporative salt enrichment causes a strong salinity anomaly under the island. We show that the TDEM field data cannot be interpreted in terms of standard one-dimensional layered-earth TDEM models, because of the strongly three-dimensional nature of the salinity anomaly. Three-dimensional interpretation of the field data allows for detailed and consistent mapping of this anomaly and makes better use of the information contained in the TDEM field

  4. Comparisons between real and complex Gauss wavelet transform methods of three-dimensional shape reconstruction

    NASA Astrophysics Data System (ADS)

    Xu, Luopeng; Dan, Youquan; Wang, Qingyuan

    2015-10-01

    The continuous wavelet transform (CWT) introduces an expandable spatial and frequency window which can overcome the inferiority of localization characteristic in Fourier transform and windowed Fourier transform. The CWT method is widely applied in the non-stationary signal analysis field including optical 3D shape reconstruction with remarkable performance. In optical 3D surface measurement, the performance of CWT for optical fringe pattern phase reconstruction usually depends on the choice of wavelet function. A large kind of wavelet functions of CWT, such as Mexican Hat wavelet, Morlet wavelet, DOG wavelet, Gabor wavelet and so on, can be generated from Gauss wavelet function. However, so far, application of the Gauss wavelet transform (GWT) method (i.e. CWT with Gauss wavelet function) in optical profilometry is few reported. In this paper, the method using GWT for optical fringe pattern phase reconstruction is presented first and the comparisons between real and complex GWT methods are discussed in detail. The examples of numerical simulations are also given and analyzed. The results show that both the real GWT method along with a Hilbert transform and the complex GWT method can realize three-dimensional surface reconstruction; and the performance of reconstruction generally depends on the frequency domain appearance of Gauss wavelet functions. For the case of optical fringe pattern of large phase variation with position, the performance of real GWT is better than that of complex one due to complex Gauss series wavelets existing frequency sidelobes. Finally, the experiments are carried out and the experimental results agree well with our theoretical analysis.

  5. Energy management of three-dimensional minimum-time intercept. [for aircraft flight optimization

    NASA Technical Reports Server (NTRS)

    Kelley, H. J.; Cliff, E. M.; Visser, H. G.

    1985-01-01

    A real-time computer algorithm to control and optimize aircraft flight profiles is described and applied to a three-dimensional minimum-time intercept mission. The proposed scheme has roots in two well known techniques: singular perturbations and neighboring-optimal guidance. Use of singular-perturbation ideas is made in terms of the assumed trajectory-family structure. A heading/energy family of prestored point-mass-model state-Euler solutions is used as the baseline in this scheme. The next step is to generate a near-optimal guidance law that will transfer the aircraft to the vicinity of this reference family. The control commands fed to the autopilot (bank angle and load factor) consist of the reference controls plus correction terms which are linear combinations of the altitude and path-angle deviations from reference values, weighted by a set of precalculated gains. In this respect the proposed scheme resembles neighboring-optimal guidance. However, in contrast to the neighboring-optimal guidance scheme, the reference control and state variables as well as the feedback gains are stored as functions of energy and heading in the present approach. Some numerical results comparing open-loop optimal and approximate feedback solutions are presented.

  6. Parallel Computation and Visualization of Three-dimensional, Time-dependent, Thermal Convective Flows

    NASA Technical Reports Server (NTRS)

    Wang, P.; Li, P.

    1998-01-01

    A high-resolution numerical study on parallel systems is reported on three-dimensional, time-dependent, thermal convective flows. A parallel implentation on the finite volume method with a multigrid scheme is discussed, and a parallel visualization systemm is developed on distributed systems for visualizing the flow.

  7. Development of a three-dimensional time-dependent flow field model

    NASA Technical Reports Server (NTRS)

    Farmer, R. C.; Waldrop, W. R.; Pitts, F. H.; Shah, K. R.

    1975-01-01

    A three-dimensional, time-dependent mathematical model to represent Mobile Bay was developed. Computer programs were developed which numerically solve the appropriate conservation equations for predicting bay and estuary flow fields. The model is useful for analyzing the dispersion of sea water into fresh water and the transport of sediment, and for relating field and physical model data.

  8. Time-marching methods for three-dimensional steady and unsteady viscous imcompressible flows

    NASA Technical Reports Server (NTRS)

    Hsu, C.-H.; Chen, Y.-M.; Liu, C. H.

    1991-01-01

    An implicit algorithm for the solution of three-dimensional, steady and unsteady, viscous, incompressible flows is presented. The algorithm is based on an upwind-relaxation finite-difference method. Steady-state solutions are carried out using a time-marching solution technique in combination with a local time-stepping strategy. To obtain time-accurate solutions, a subiterative procedure is employed at each physical time step using a global time step to ensure the divergence-free condition. Steady-state flows in several straight ducts and in a square duct with a 90-degree bend are computed and compared with analytical and experimental results. The classical problem of starting flow in a circular pipe is chosen to verify the time accuracy of the present scheme. Finally, the three-dimensional bubble-type vortex breakdown of a slender cylindrical vortex in an unbounded flow is investigated.

  9. Hologram synthesis of three-dimensional real objects using portable integral imaging camera.

    PubMed

    Lee, Sung-Keun; Hong, Sung-In; Kim, Yong-Soo; Lim, Hong-Gi; Jo, Na-Young; Park, Jae-Hyeung

    2013-10-01

    We propose a portable hologram capture system based on integral imaging. An integral imaging camera with an integrated micro lens array captures spatio-angular light ray distribution of the three-dimensional scene under incoherent illumination. The captured light ray distribution is then processed to synthesize corresponding hologram. Experimental results show that the synthesized hologram is optically reconstructed successfully, demonstrating accommodation and motion parallax of the reconstructed three-dimensional scene.

  10. Acetazolamide challenge for three-dimensional time-of-flight MR angiography of the brain

    SciTech Connect

    Mandai, Kenji; Sueyoshi, Kenji; Fukunaga, Ryuzo; Nukada, Masaru; Ohtani, Fumio; Araki, Yutaka; Tsukaguchi, Isao; Abe, Hiroshi )

    1994-04-01

    We compared three-dimensional time-of-flight MR angiograms obtained before and after acetazolamide administration to evaluate whether use of this drug could improve visualization of small peripheral intracranial arteries and atherosclerotic stenosis. For evaluation of small peripheral arteries, 10 patients with clinical diagnosis of ischemic cerebrovascular disease and 10 healthy volunteers were investigated, and for evaluation of stenosis, another 6 patients were investigated. Vascular images were obtained by three-dimensional time-of-flight MR angiography. After a baseline scan, 17 mg/kg acetazolamide was injected intravenously and the second scan was performed 20 minutes later. Several small peripheral arteries that had not been seen on the baseline images were visible on the acetazolamide images without any augmentation of the background signals. Stenotic lesions in the main trunks of the major cerebral arteries were detected more clearly on acetazolamide images. Acetazolamide improves visualization of small peripheral intracranial arteries and sensitivity in detecting atherosclerotic stenosis in the main trunk of major cerebral artery by three-dimensional time-of-flight MR angiography without changing MR apparatus and software. 15 refs., 5 figs., 2 tabs.

  11. Time-reversal invariant SU(2 ) Hofstadter problem in three-dimensional lattices

    NASA Astrophysics Data System (ADS)

    Li, Yi

    2015-05-01

    We formulate the three-dimensional SU(2 ) Landau level problem in cubic lattices with time-reversal invariance. By taking a Landau-type SU(2 ) gauge, the system can be reduced into one dimension, as characterized by the SU(2 ) generalization of the usual Harper equations with a periodic spin-dependent gauge potential. The surface spectra indicate the spatial separation of helical states with opposite eigenvalues of a lattice helicity operator. The band topology is investigated from both the analysis of the boundary helical Fermi surfaces and the calculation of the Z2 index based on the bulk wave functions. The transition between a three-dimensional weak topological insulator to a strong one is studied as varying the anisotropy of hopping parameters.

  12. A Three-Dimensional Parallel Time-Accurate Turbopump Simulation Procedure Using Overset Grid System

    NASA Technical Reports Server (NTRS)

    Kiris, Cetin; Chan, William; Kwak, Dochan

    2002-01-01

    The objective of the current effort is to provide a computational framework for design and analysis of the entire fuel supply system of a liquid rocket engine, including high-fidelity unsteady turbopump flow analysis. This capability is needed to support the design of pump sub-systems for advanced space transportation vehicles that are likely to involve liquid propulsion systems. To date, computational tools for design/analysis of turbopump flows are based on relatively lower fidelity methods. An unsteady, three-dimensional viscous flow analysis tool involving stationary and rotational components for the entire turbopump assembly has not been available for real-world engineering applications. The present effort provides developers with information such as transient flow phenomena at start up, and nonuniform inflows, and will eventually impact on system vibration and structures. In the proposed paper, the progress toward the capability of complete simulation of the turbo-pump for a liquid rocket engine is reported. The Space Shuttle Main Engine (SSME) turbo-pump is used as a test case for evaluation of the hybrid MPI/Open-MP and MLP versions of the INS3D code. CAD to solution auto-scripting capability is being developed for turbopump applications. The relative motion of the grid systems for the rotor-stator interaction was obtained using overset grid techniques. Unsteady computations for the SSME turbo-pump, which contains 114 zones with 34.5 million grid points, are carried out on Origin 3000 systems at NASA Ames Research Center. Results from these time-accurate simulations with moving boundary capability are presented along with the performance of parallel versions of the code.

  13. A Three Dimensional Parallel Time Accurate Turbopump Simulation Procedure Using Overset Grid Systems

    NASA Technical Reports Server (NTRS)

    Kiris, Cetin; Chan, William; Kwak, Dochan

    2001-01-01

    The objective of the current effort is to provide a computational framework for design and analysis of the entire fuel supply system of a liquid rocket engine, including high-fidelity unsteady turbopump flow analysis. This capability is needed to support the design of pump sub-systems for advanced space transportation vehicles that are likely to involve liquid propulsion systems. To date, computational tools for design/analysis of turbopump flows are based on relatively lower fidelity methods. An unsteady, three-dimensional viscous flow analysis tool involving stationary and rotational components for the entire turbopump assembly has not been available for real-world engineering applications. The present effort provides developers with information such as transient flow phenomena at start up, and non-uniform inflows, and will eventually impact on system vibration and structures. In the proposed paper, the progress toward the capability of complete simulation of the turbo-pump for a liquid rocket engine is reported. The Space Shuttle Main Engine (SSME) turbo-pump is used as a test case for evaluation of the hybrid MPI/Open-MP and MLP versions of the INS3D code. CAD to solution auto-scripting capability is being developed for turbopump applications. The relative motion of the grid systems for the rotor-stator interaction was obtained using overset grid techniques. Unsteady computations for the SSME turbo-pump, which contains 114 zones with 34.5 million grid points, are carried out on Origin 3000 systems at NASA Ames Research Center. Results from these time-accurate simulations with moving boundary capability will be presented along with the performance of parallel versions of the code.

  14. Three-dimensional vision for real-time produce grading

    NASA Astrophysics Data System (ADS)

    Bailey, Donald G.; Mercer, Ken; Plaw, Colin; Ball, Ralph; Barraclough, Harvey

    2002-02-01

    Produce is often sold by weight, so one of the roles of the grading system is to allocate each item to a particular chute for packing into fixed weight bundles. Accurate, high- speed weight measurement is difficult and expensive, so machine vision is used to estimate the weight of each item. Previous estimations relied on a single diameter measurement, which resulted in large errors. To ensure that the minimum weight was provided, each bundle was on average 30% overweight. By improving the accuracy of the estimation, and combining this with an improved chute allocation strategy, significant savings can be made. The weight estimation in the system under development is based on the projected area of each item. The error in weight estimation was further improved by measuring the projected area from two perpendicular views. With the produce being sorted at a rate of 12 to 15 items per second, there are significant challenges in obtaining and processing the simultaneous perpendicular views of each item. The two views are captured of the item through the use of mirrors, and a third direct view is also obtained for quality grading purposes.

  15. Nonlinear teleseismic tomography at Long Valley caldera, using three-dimensional minimum travel time ray tracing

    SciTech Connect

    Weiland, C.M.; Steck, L.K.; Dawson, P.B.

    1995-10-10

    The authors explore the impact of three-dimensional minimum travel time ray tracing on nonlinear teleseismic inversion. This problem has particular significance when trying to image strongly contrasting low-velocity bodies, such as magma chambers, because strongly refracted/and/or diffracted rays may precede the direct P wave arrival traditionally used in straight-ray seismic tomography. They use a simplex-based ray tracer to compute the three-dimensional, minimum travel time ray paths and employ an interative technique to cope with nonlinearity. Results from synthetic data show that their algorithm results in better model reconstructions compared with traditional straight-ray inversions. The authors reexamine the teleseismic data collected at Long Valley caldera by the U.S. Geological Survey. The most prominent feature of their result is a 25-30% low-velocity zone centered at 11.5 km depth beneath the northwestern quandrant of the caldera. Beneath this at a depth of 24.5 km is a more diffuse 15% low-velocity zone. In general, the low velocities tend to deepen to the south and east. The authors interpret the shallow feature to be the residual Long Valley caldera magma chamber, while the deeper feature may represent basaltic magmas ponded in the midcrust. The deeper position of the prominent low-velocity region in comparison to earlier tomographic images is a result of using three-dimensional rays rather than straight rays in the ray tracing. The magnitude of the low-velocity anomaly is a factor of {approximately}3 times larger than earlier models from linear arrival time inversions and is consistent with models based on observations of ray bending at sites within the caldera. These results imply the presence of anywhere from 7 to 100% partial melt beneath the caldera. 40 refs., 1 fig., 1 tab.

  16. Time-of-flight compressed-sensing ultrafast photography for encrypted three-dimensional dynamic imaging

    NASA Astrophysics Data System (ADS)

    Liang, Jinyang; Gao, Liang; Hai, Pengfei; Li, Chiye; Wang, Lihong V.

    2016-02-01

    We applied compressed ultrafast photography (CUP), a computational imaging technique, to acquire three-dimensional (3D) images. The approach unites image encryption, compression, and acquisition in a single measurement, thereby allowing efficient and secure data transmission. By leveraging the time-of-flight (ToF) information of pulsed light reflected by the object, we can reconstruct a volumetric image (150 mm×150 mm×1050 mm, x × y × z) from a single camera snapshot. Furthermore, we demonstrated high-speed 3D videography of a moving object at 75 frames per second using the ToF-CUP camera.

  17. Differential time domain method improves performance of pulsed laser ranging and three-dimensional imaging.

    PubMed

    Cao, Jie; Hao, Qun; Cheng, Yang; Peng, Yuxin; Zhang, Kaiyu; Mu, Jiaxing; Wang, Peng

    2016-01-10

    A ranging method based on the differential time domain method (DTDM) is proposed in order to improve ranging accuracy and the range of active measurement based on peak discriminator (PD). We develop mathematical models and deduce that zero-crossing sensitivity is an important factor, which affects the ranging error of DTDM. Additionally, zero-crossing sensitivity is determined by delayed time. We carried out relative experiments and obtained the smallest ranging error when delayed time is receiving pulse width. We also compare ranging, three-dimensional (3D) point clouds and depth images based on two methods under same testing conditions. The results show that DTDM is beneficial in improving performance of pulse laser ranging and 3D imaging.

  18. Differential time domain method improves performance of pulsed laser ranging and three-dimensional imaging.

    PubMed

    Cao, Jie; Hao, Qun; Cheng, Yang; Peng, Yuxin; Zhang, Kaiyu; Mu, Jiaxing; Wang, Peng

    2016-01-10

    A ranging method based on the differential time domain method (DTDM) is proposed in order to improve ranging accuracy and the range of active measurement based on peak discriminator (PD). We develop mathematical models and deduce that zero-crossing sensitivity is an important factor, which affects the ranging error of DTDM. Additionally, zero-crossing sensitivity is determined by delayed time. We carried out relative experiments and obtained the smallest ranging error when delayed time is receiving pulse width. We also compare ranging, three-dimensional (3D) point clouds and depth images based on two methods under same testing conditions. The results show that DTDM is beneficial in improving performance of pulse laser ranging and 3D imaging. PMID:26835773

  19. The distribution of "time of flight" in three dimensional stationary chaotic advection

    NASA Astrophysics Data System (ADS)

    Raynal, Florence; Carrière, Philippe

    2015-04-01

    The distributions of "time of flight" (time spent by a single fluid particle between two crossings of the Poincaré section) are investigated for five different three dimensional stationary chaotic mixers. Above all, we study the large tails of those distributions and show that mainly two types of behaviors are encountered. In the case of slipping walls, as expected, we obtain an exponential decay, which, however, does not scale with the Lyapunov exponent. Using a simple model, we suggest that this decay is related to the negative eigenvalues of the fixed points of the flow. When no-slip walls are considered, as predicted by the model, the behavior is radically different, with a very large tail following a power law with an exponent close to -3.

  20. The distribution of “time of flight” in three dimensional stationary chaotic advection

    SciTech Connect

    Raynal, Florence; Carrière, Philippe

    2015-04-15

    The distributions of “time of flight” (time spent by a single fluid particle between two crossings of the Poincaré section) are investigated for five different three dimensional stationary chaotic mixers. Above all, we study the large tails of those distributions and show that mainly two types of behaviors are encountered. In the case of slipping walls, as expected, we obtain an exponential decay, which, however, does not scale with the Lyapunov exponent. Using a simple model, we suggest that this decay is related to the negative eigenvalues of the fixed points of the flow. When no-slip walls are considered, as predicted by the model, the behavior is radically different, with a very large tail following a power law with an exponent close to −3.

  1. Time-resolved mirage method: A three-dimensional theory and experiments

    NASA Astrophysics Data System (ADS)

    Astrath, N. G. C.; Malacarne, L. C.; Bernabe, H. S.; Baesso, M. L.; Jacinto, C.

    2012-05-01

    A general time-resolved three-dimensional theory of the photothermal beam deflection for the measurement of thermal properties of opaque materials is presented. We derive the analytical solutions for the laser induced temperature profiles in the sample and in the fluid above the sample assuming flux discontinuity at the interface sample/fluid. We compare the analytical solutions with all numerical modeling using finite element analysis. The photothermal deflection signal is calculated and an expression is provided for the transverse photothermal signal at a position-sensing detector. We use the model and the experimental method to investigate opaque plastic and metals, and the results for the thermal properties of the samples are in an excellent agreement in the literature values.

  2. Encrypted Three-dimensional Dynamic Imaging using Snapshot Time-of-flight Compressed Ultrafast Photography.

    PubMed

    Liang, Jinyang; Gao, Liang; Hai, Pengfei; Li, Chiye; Wang, Lihong V

    2015-01-01

    Compressed ultrafast photography (CUP), a computational imaging technique, is synchronized with short-pulsed laser illumination to enable dynamic three-dimensional (3D) imaging. By leveraging the time-of-flight (ToF) information of pulsed light backscattered by the object, ToF-CUP can reconstruct a volumetric image from a single camera snapshot. In addition, the approach unites the encryption of depth data with the compressed acquisition of 3D data in a single snapshot measurement, thereby allowing efficient and secure data storage and transmission. We demonstrated high-speed 3D videography of moving objects at up to 75 volumes per second. The ToF-CUP camera was applied to track the 3D position of a live comet goldfish. We have also imaged a moving object obscured by a scattering medium. PMID:26503834

  3. Encrypted Three-dimensional Dynamic Imaging using Snapshot Time-of-flight Compressed Ultrafast Photography.

    PubMed

    Liang, Jinyang; Gao, Liang; Hai, Pengfei; Li, Chiye; Wang, Lihong V

    2015-10-27

    Compressed ultrafast photography (CUP), a computational imaging technique, is synchronized with short-pulsed laser illumination to enable dynamic three-dimensional (3D) imaging. By leveraging the time-of-flight (ToF) information of pulsed light backscattered by the object, ToF-CUP can reconstruct a volumetric image from a single camera snapshot. In addition, the approach unites the encryption of depth data with the compressed acquisition of 3D data in a single snapshot measurement, thereby allowing efficient and secure data storage and transmission. We demonstrated high-speed 3D videography of moving objects at up to 75 volumes per second. The ToF-CUP camera was applied to track the 3D position of a live comet goldfish. We have also imaged a moving object obscured by a scattering medium.

  4. A scale dependent black hole in three-dimensional space–time

    NASA Astrophysics Data System (ADS)

    Koch, Benjamin; Reyes, Ignacio A.; Rincón, Ángel

    2016-11-01

    Scale dependence at the level of the effective action is a generic result of quantum field theory. Allowing for scale dependence of the gravitational couplings leads to a generalization of the corresponding field equations. In this work, those equations are solved by imposing the ‘null energy condition’ in three-dimensional space time with stationary spherical symmetry. The constants of integration are given in terms of the classical BTZ parameters plus one additional constant, that parametrizes the strength of the scale dependence. The properties such as asymptotics, horizon structure, and thermodynamics are discussed. It is found that the black hole entropy shows a remarkable transition from the usual ‘area law’ to an ‘area × radius’ law.

  5. Encrypted Three-dimensional Dynamic Imaging using Snapshot Time-of-flight Compressed Ultrafast Photography

    NASA Astrophysics Data System (ADS)

    Liang, Jinyang; Gao, Liang; Hai, Pengfei; Li, Chiye; Wang, Lihong V.

    2015-10-01

    Compressed ultrafast photography (CUP), a computational imaging technique, is synchronized with short-pulsed laser illumination to enable dynamic three-dimensional (3D) imaging. By leveraging the time-of-flight (ToF) information of pulsed light backscattered by the object, ToF-CUP can reconstruct a volumetric image from a single camera snapshot. In addition, the approach unites the encryption of depth data with the compressed acquisition of 3D data in a single snapshot measurement, thereby allowing efficient and secure data storage and transmission. We demonstrated high-speed 3D videography of moving objects at up to 75 volumes per second. The ToF-CUP camera was applied to track the 3D position of a live comet goldfish. We have also imaged a moving object obscured by a scattering medium.

  6. Three-Dimensional Navier-Stokes Calculations Using the Modified Space-Time CESE Method

    NASA Technical Reports Server (NTRS)

    Chang, Chau-lyan

    2007-01-01

    The space-time conservation element solution element (CESE) method is modified to address the robustness issues of high-aspect-ratio, viscous, near-wall meshes. In this new approach, the dependent variable gradients are evaluated using element edges and the corresponding neighboring solution elements while keeping the original flux integration procedure intact. As such, the excellent flux conservation property is retained and the new edge-based gradients evaluation significantly improves the robustness for high-aspect ratio meshes frequently encountered in three-dimensional, Navier-Stokes calculations. The order of accuracy of the proposed method is demonstrated for oblique acoustic wave propagation, shock-wave interaction, and hypersonic flows over a blunt body. The confirmed second-order convergence along with the enhanced robustness in handling hypersonic blunt body flow calculations makes the proposed approach a very competitive CFD framework for 3D Navier-Stokes simulations.

  7. A three-dimensional, time-dependent model of Mobile Bay

    NASA Technical Reports Server (NTRS)

    Pitts, F. H.; Farmer, R. C.

    1976-01-01

    A three-dimensional, time-variant mathematical model for momentum and mass transport in estuaries was developed and its solution implemented on a digital computer. The mathematical model is based on state and conservation equations applied to turbulent flow of a two-component, incompressible fluid having a free surface. Thus, bouyancy effects caused by density differences between the fresh and salt water, inertia from thare river and tidal currents, and differences in hydrostatic head are taken into account. The conservation equations, which are partial differential equations, are solved numerically by an explicit, one-step finite difference scheme and the solutions displayed numerically and graphically. To test the validity of the model, a specific estuary for which scaled model and experimental field data are available, Mobile Bay, was simulated. Comparisons of velocity, salinity and water level data show that the model is valid and a viable means of simulating the hydrodynamics and mass transport in non-idealized estuaries.

  8. Investigation and evaluation of a computer program to minimize three-dimensional flight time tracks

    NASA Technical Reports Server (NTRS)

    Parke, F. I.

    1981-01-01

    The program for the DC 8-D3 flight planning was slightly modified for the three dimensional flight planning for DC 10 aircrafts. Several test runs of the modified program over the North Atlantic and North America were made for verifying the program. While geopotential height and temperature were used in a previous program as meteorological data, the modified program uses wind direction and speed and temperature received from the National Weather Service. A scanning program was written to collect required weather information from the raw data received in a packed decimal format. Two sets of weather data, the 12-hour forecast and 24-hour forecast based on 0000 GMT, are used for dynamic processes in testruns. In order to save computing time only the weather data of the North Atlantic and North America is previously stored in a PCF file and then scanned one by one.

  9. Three-dimensional time-resolved optical mammography of the uncompressed breast

    NASA Astrophysics Data System (ADS)

    Enfield, Louise C.; Gibson, Adam P.; Everdell, Nicholas L.; Delpy, David T.; Schweiger, Martin; Arridge, Simon R.; Richardson, Caroline; Keshtgar, Mohammad; Douek, Michael; Hebden, Jeremy C.

    2007-06-01

    Optical tomography is being developed as a means of detecting and specifying disease in the adult female breast. We present a series of clinical three-dimensional optical images obtained with a 32-channel time-resolved system and a liquid-coupled interface. Patients place their breasts in a hemispherical cup to which sources and detectors are coupled, and the remaining space is filled with a highly scattering fluid. A cohort of 38 patients has been scanned, with a variety of benign and malignant lesions. Images show that hypervascularization associated with tumors provides very high contrast due to increased absorption by hemoglobin. Only half of the fibroadenomas scanned could be observed, but of those that could be detected, all but one revealed an apparent increase in blood volume and a decrease in scatter and oxygen saturation.

  10. Three-dimensional time-resolved optical mammography of the uncompressed breast

    SciTech Connect

    Enfield, Louise C.; Gibson, Adam P.; Everdell, Nicholas L.; Delpy, David T.; Schweiger, Martin; Arridge, Simon R.; Richardson, Caroline; Keshtgar, Mohammad; Douek, Michael; Hebden, Jeremy C

    2007-06-10

    Optical tomography is being developed as a means of detecting and specifying disease in the adult female breast. We present a series of clinical three-dimensional optical images obtained with a 32-channel time-resolvedsystem and a liquid-coupled interface. Patients place their breasts in a hemispherical cup to whichsources and detectors are coupled, and the remaining space is filled with a highly scattering fluid. Acohort of 38 patients has been scanned, with a variety of benign and malignant lesions. Images show that hypervascularization associated with tumors provides very high contrast due to increased absorption by hemoglobin. Only half of the fibroadenomas scanned could be observed, but of those that could bedetected, all but one revealed an apparent increase in blood volume and a decrease in scatter and oxygen saturation.

  11. Encrypted Three-dimensional Dynamic Imaging using Snapshot Time-of-flight Compressed Ultrafast Photography

    PubMed Central

    Liang, Jinyang; Gao, Liang; Hai, Pengfei; Li, Chiye; Wang, Lihong V.

    2015-01-01

    Compressed ultrafast photography (CUP), a computational imaging technique, is synchronized with short-pulsed laser illumination to enable dynamic three-dimensional (3D) imaging. By leveraging the time-of-flight (ToF) information of pulsed light backscattered by the object, ToF-CUP can reconstruct a volumetric image from a single camera snapshot. In addition, the approach unites the encryption of depth data with the compressed acquisition of 3D data in a single snapshot measurement, thereby allowing efficient and secure data storage and transmission. We demonstrated high-speed 3D videography of moving objects at up to 75 volumes per second. The ToF-CUP camera was applied to track the 3D position of a live comet goldfish. We have also imaged a moving object obscured by a scattering medium. PMID:26503834

  12. Shape complexity of whole-field three-dimensional space-time fluid interfaces in turbulence

    NASA Astrophysics Data System (ADS)

    Catrakis, Haris J.; Aguirre, Roberto C.; Ruiz-Plancarte, Jesus; Thayne, Robert D.

    2002-11-01

    A shape-complexity measure, Omega]d)([lambda, is proposed to quantify the behavior of turbulence-generated fluid interfaces in d dimensions as a function of scale lambda in terms of a generalized area-volume ratio. This shape complexity provides a dimensionless measure of the interfacial contributions at scales larger than or equal to lambda. This is useful, for example, to quantify the interfacial area in three dimensions or the contour length in two dimensions, facilitating a comparison of three-dimensional interfaces to two-dimensional interfacial transects. Application to mixed-fluid interfaces derived from three-dimensional approx10003 space-time measurements above the mixing transition in turbulent jets, at Reynolds number Reapprox20 000 and Schmidt number Scapprox2000, shows that both Omega]3)([lambda and Omega]2)([lambda increase continuously with decreasing scale and have scaling exponents alpha(sub Omega3) and alpha(sub Omega2) which depend on scale. It is argued that this scale dependence corresponds to the cumulative interfacial dynamics and structure. At intermediate scales, the shape-complexity exponent of the space-time interfaces is found to be larger in three dimensions compared to two dimensions, i.e., alpha(sub Omega]3))([lambda]>[alpha(sub Omega]2))([lambda, consistent with previous comparisons between two-dimensional and one-dimensional interfacial transects. This behavior is attributable to the relative contributions of large-scale folding and small-scale wrinkling to the interfacial shape complexity, and may be expected to be Reynolds-number and Schmidt-number dependent. The shape complexity Omega]d)([lambda provides a way to compare quantitatively the behavior of interfaces across the range of scales and in different dimensions, in a given flow or in different flows.

  13. Interferograms, schlieren, and shadowgraphs constructed from real- and ideal-gas, two- and three-dimensional computed flowfields

    NASA Technical Reports Server (NTRS)

    Yates, Leslie A.

    1993-01-01

    The construction of interferograms, schlieren, and shadowgraphs from computed flowfield solutions permits one-to-one comparisons of computed and experimental results. A method of constructing these images from both ideal- and real-gas, two and three-dimensional computed flowfields is described. The computational grids can be structured or unstructured, and multiple grids are an option. Constructed images are shown for several types of computed flows including nozzle, wake, and reacting flows; comparisons to experimental images are also shown. In addition, th sensitivity of these images to errors in the flowfield solution is demonstrated, and the constructed images can be used to identify problem areas in the computations.

  14. Interferograms, Schlieren, and Shadowgraphs Constructed from Real- and Ideal-Gas, Two- and Three-Dimensional Computed Flowfields

    NASA Technical Reports Server (NTRS)

    Yates, Leslie A.

    1992-01-01

    The construction of interferograms, schlieren, and shadowgraphs from computed flowfield solutions permits one-to-one comparisons of computed and experimental results. A method for constructing these images from both ideal- and real-gas, two- and three-dimensional computed flowfields is described. The computational grids can be structured or unstructured, and multiple grids are an option. Constructed images are shown for several types of computed flows including nozzle, wake, and reacting flows; comparisons to experimental images are also shown. In addition, the sensitivity of these images to errors in the flowfield solution is demonstrated, and the constructed images can be used to identify problem areas in the computations.

  15. Analysis and numerical simulation of a real cell merger using a three-dimensional cloud resolving model

    NASA Astrophysics Data System (ADS)

    Karacostas, T.; Spiridonov, V.; Bampzelis, D.; Pytharoulis, I.; Tegoulias, I.; Tymbanidis, K.

    2016-03-01

    A three-dimensional cloud resolving model is used to study a real cell merger case that occurred on 10 August, 2008 over north-central Greece, causing heavy rainfall, hailfall and high-frequency lightning. Firstly, the storm is observed, analyzed and recorded using a C-band weather radar. Secondly, three distinct simulations are performed using a cloud resolving model. An unseeded simulation, in order to test the ability of the model to reproduce the structural and evolutionary properties of the storm and two seeded simulations in which seeding occurred before and after cell merging. Reflectivity fields are analyzed, horizontally and vertically, at different simulation times. The 3-D numerical simulations suggest that the merger process occurred by two or three isolated single-cells and formed during their SW-NE motion. The merging process apparently alters dynamical and microphysical properties through low and middle level forcing; increases cloud diameters and cloud depths, producing more graupel and ice particles and increases radar reflectivity values. Processed radar images depict a similar view of the storm structure, evolution and interactions of such merging processes. The model calculated maximum radar reflectivity values coincide with the recorded ones. Results indicate that seeding the cloud before its merging produces more positive effects on hail suppression than seeding after merging. These findings are quite important, in order to document the value of the cloud resolving model and its capability to simulate and reproduce the realistic storm processes and to provide a better understanding of the cloud dynamical and microphysical features related to different seeding approaches.

  16. Developmental critical windows and sensitive periods as three-dimensional constructs in time and space.

    PubMed

    Burggren, Warren W; Mueller, Casey A

    2015-01-01

    A critical window (sensitive period) represents a period during development when an organism's phenotype is responsive to intrinsic or extrinsic (environmental) factors. Such windows represent a form of developmental phenotypic plasticity and result from the interaction between genotype and environment. Critical windows have typically been defined as comprising discrete periods in development with a distinct starting time and end time, as identified by experiments following an on and an off protocol. Yet in reality, periods of responsiveness during development are likely more ambiguous that depicted. Our goal is to extend the concept of the developmental critical window by introducing a three-dimensional construct in which time during development, dose of the stressor applied, and the resultant phenotypic modification can be utilized to more realistically define a critical window. Using the example of survival of the brine shrimp (Artemia franciscana) during exposure to different salinity levels during development, we illustrate that it is not just stressor dose or exposure time but the interaction of these two factors that results in the measured phenotypic change, which itself may vary within a critical window. We additionally discuss a systems approach to critical windows, in which the components of a developing system--whether they be molecular, physiological, or morphological--may show differing responses with respect to time and dose. Thus, the plasticity of each component may contribute to a broader overall system response. PMID:25730265

  17. A three-dimensional robust nonlinear terminal guidance law with ISS finite-time convergence

    NASA Astrophysics Data System (ADS)

    Li, Guilin; Ji, Haibo

    2016-05-01

    This paper presents a novel three-dimensional nonlinear terminal guidance law with finite-time convergence for intercepting manoeuvring targets. Different from the usual method of decoupling the missile-target relative motion into two-dimensional planes, this law is designed via using the coupled dynamics. The guidance law is derived based on the theory of finite-time input-to-state stability (ISS), which needs no assumption of the linearisation and the estimation of target accelerations. Under this law, the line-of-sight angular rates can be stabilised to a small domain of convergence around zero in finite time. The convergence rate and convergence domain can be adjusted by changing the guidance parameters. First, a sufficient condition on finite-time ISS of the guidance system is given, and is subsequently used to design the guidance law. Finally, simulation results are provided to show that the proposed guidance law possesses fast convergence rate and strong robustness to target manoeuvres.

  18. Gender Differences in Object Location Memory in a Real Three-Dimensional Environment

    ERIC Educational Resources Information Center

    Iachini, Tina; Sergi, Ida; Ruggiero, Gennaro; Gnisci, Augusto

    2005-01-01

    In this preliminary study we investigate gender differences in object location memory. Our purpose is to extend the results about object location memory obtained in laboratory settings to a real 3-D environment and to further distinguish the specific components involved in this kind of memory by considering the strategies adopted to perform the…

  19. Holocinematographic velocimeter for measuring time-dependent, three-dimensional flows

    NASA Technical Reports Server (NTRS)

    Beeler, George B.; Weinstein, Leonard M.

    1987-01-01

    Two simulatneous, orthogonal-axis holographic movies are made of tracer particles in a low-speed water tunnel to determine the time-dependent, three-dimensional velocity field. This instrument is called a Holocinematographic Velocimeter (HCV). The holographic movies are reduced to the velocity field with an automatic data reduction system. This permits the reduction of large numbers of holograms (time steps) in a reasonable amount of time. The current version of the HCV, built for proof-of-concept tests, uses low-frame rate holographic cameras and a prototype of a new type of water tunnel. This water tunnel is a unique low-disturbance facility which has minimal wall effects on the flow. This paper presents the first flow field examined by the HCV, the two-dimensional von Karman vortex street downstream of an unswept circular cylinder. Key factors in the HCV are flow speed, spatial and temporal resolution required, measurement volume, film transport speed, and laser pulse length. The interactions between these factors are discussed.

  20. A time accurate finite volume high resolution scheme for three dimensional Navier-Stokes equations

    NASA Technical Reports Server (NTRS)

    Liou, Meng-Sing; Hsu, Andrew T.

    1989-01-01

    A time accurate, three-dimensional, finite volume, high resolution scheme for solving the compressible full Navier-Stokes equations is presented. The present derivation is based on the upwind split formulas, specifically with the application of Roe's (1981) flux difference splitting. A high-order accurate (up to the third order) upwind interpolation formula for the inviscid terms is derived to account for nonuniform meshes. For the viscous terms, discretizations consistent with the finite volume concept are described. A variant of second-order time accurate method is proposed that utilizes identical procedures in both the predictor and corrector steps. Avoiding the definition of midpoint gives a consistent and easy procedure, in the framework of finite volume discretization, for treating viscous transport terms in the curvilinear coordinates. For the boundary cells, a new treatment is introduced that not only avoids the use of 'ghost cells' and the associated problems, but also satisfies the tangency conditions exactly and allows easy definition of viscous transport terms at the first interface next to the boundary cells. Numerical tests of steady and unsteady high speed flows show that the present scheme gives accurate solutions.

  1. Tomographic imaging of local earthquake delay times for three-dimensional velocity variation in western Washington

    SciTech Connect

    Lees, J.M.; Crosson, R.S. )

    1990-04-10

    Tomographic inversion is applied to delay times from local earthquakes to image three dimensional velocity variations in the Puget Sound region of western Washington. The 37,500 square km region is represented by nearly cubic blocks of 5 km per side. P-wave arrival time observations from 4,387 crustal earthquakes, with depths of 0 to 40 km, were used as sources producing 36,865 rays covering the target region. A conjugate gradient method (LSQR) is used to invert the large, sparse system of equations. To diminish the effects of noisy data, the Laplacian is constrained to be zero within horizontal layers, providing smoothing of the model. The resolution is estimated by calculating impulse responses at blocks of interest and estimates of standard errors are calculated by the jackknife statistical procedure. Results of the inversion are correlated with some known geologic features and independent geophysical measurements. High P-wave velocities along the eastern flank of the Olympic Peninsula are interpreted to reflect the subsurface extension of Crescent terrane. Low velocities beneath the Puget Sound further to the east are inferred to reflect thick sediment accumulations. The Crescent terrane appears to extend beneath Puget Sound, consistent with its interpretation as a major accretionary unit. In the southern Puget Sound basin, high velocity anomalies at depths of 10-20 km are interpreted as Crescent terrane and are correlated with a region of low seismicity. Near Mt. Ranier, high velocity anomalies may reflect buried plutons.

  2. Three-dimensional crustal structure of the Mendocino Triple Junction region from local earthquake travel times

    NASA Astrophysics Data System (ADS)

    Verdonck, David; Zandt, George

    1994-12-01

    The large-scale, three-dimensional geometry of the Mendocino Triple Junction at Cape Mendocino, California, was investigated by inverting nearly 19,000 P wave arrival times from over 1400 local earthquakes to estimate the three-dimensional velocity structure and hypocentral parameters. A velocity grid 175 km (N-S) by 125 km (E-W) centered near Garberville, California, was constructed with 25 km horizontal and 5 km vertical mode spacing. The model was well resolved near Cape Mendocino, where the earthquakes and stations are concentrated. At about 40.6 N latitude a high-velocity gradient between 6.5 and 7.5 km/s dips gently to the south and east from about 15 km depth near the coast. Relocated hypocenters concentrate below this high gradient which we interpret as the oceanic crust of the subducted Gorda Plate. Therefore the depth to the top of the Gorda Plate near Cape Mendocino is interpreted to be approximately 15 km. The Gorda Plate appears intact and dipping approximately 8 deg eastward due to subduction and flexing downward 6 deg - 12 deg to the south. Both hypocenters and velocity structure suggest that the southern edge of the plate intersects the coastline at 40.3 N latitude and maintains a linear trend 15 deg south of east to at least 123 W longitude. The top of a large low-velocity region at 20-30 km depth extends about 50 km N-S and 75 km E-W (roughly between Garberville and Covelo) and is located above and south of the southern edge of the Gorda Plate. We interpret this low velocity area to be locally thickened crust (8-10 km) due to either local compressional forces associated with north-south compression caused by the northward impingement of the rigid Pacific Plate or by underthrusting of the base of the accretionary subduction complex at the southern terminous of the Cascadia Subduction Zone. South of Cape Mendocino and southwest of the Garberville fault, high velocities indicative of oceanic crust are detected at 15 km depth. We interpret this

  3. Metamorphosis revealed: time-lapse three-dimensional imaging inside a living chrysalis

    PubMed Central

    Lowe, Tristan; Garwood, Russell J.; Simonsen, Thomas J.; Bradley, Robert S.; Withers, Philip J.

    2013-01-01

    Studies of model insects have greatly increased our understanding of animal development. Yet, they are limited in scope to this small pool of model species: a small number of representatives for a hyperdiverse group with highly varied developmental processes. One factor behind this narrow scope is the challenging nature of traditional methods of study, such as histology and dissection, which can preclude quantitative analysis and do not allow the development of a single individual to be followed. Here, we use high-resolution X-ray computed tomography (CT) to overcome these issues, and three-dimensionally image numerous lepidopteran pupae throughout their development. The resulting models are presented in the electronic supplementary material, as are figures and videos, documenting a single individual throughout development. They provide new insight and details of lepidopteran metamorphosis, and allow the measurement of tracheal and gut volume. Furthermore, this study demonstrates early and rapid development of the tracheae, which become visible in scans just 12 h after pupation. This suggests that there is less remodelling of the tracheal system than previously expected, and is methodologically important because the tracheal system is an often-understudied character system in development. In the future, this form of time-lapse CT-scanning could allow faster and more detailed developmental studies on a wider range of taxa than is presently possible. PMID:23676900

  4. Intracranial aneurysms: Diagnostics accuracy of three-dimensional, fourier transform, time-of-flight MR angiography

    SciTech Connect

    Korogi, Yukunori; Takahashi, Mutsumasa; Mabuchi, Nobuhisa; Miki, Hitoshi; Fujiwara, Satoru; Horikawa, Yoshiharu; Nakagawa, Toshio; O`Uchi, Toshihiro; Watabe, Tsuneya; Shiga, Hayao

    1994-10-01

    To assess the accuracy of three-dimensional, Fourier transform, time-of-flight magnetic resonance (MR) angiography in the identification of intracranial aneurysms. MR angiograms of 126 patients (59 male and 67 female patients, aged 12-77 years) with various intracranial vascular lesions were evaluated. Seventy-eight aneurysms, including 60 less than 5 mm in diameter, in 61 patients were depicted at conventional angiography. Eight projection images, as well as one axial collapsed MR angiogram obtained with a maximum-intensity projection algorithm, were used for evaluation. Sensitivity for the five observers ranged from 58% to 68% (mean, 63%). Higher sensitivity was achieved for anterior communicating and middle cerebral artery aneurysms, while that for internal carotid artery aneurysms was poor. Sensitivities for small and medium aneurysms ranged from 50% to 60% (mean, 56%) and from 77% to 94% (mean, 85%), respectively. MR angiography can depict intracranial aneurysms 5 mm or larger with good accuracy but is less useful for the identification of smaller aneurysms. 12 refs., 5 figs., 5 tabs.

  5. [Optimization of Three-dimensional Ultrashort Echo Time Magnetic Resonance Imaging at a Low Field].

    PubMed

    Huang, Yuli; Du, Yiping

    2015-12-01

    Conventional magnetic resonance (MR) pulse sequences typically have an echo time (TE) of 1 ms or longer, providing an excellent contrast between different soft tissues. However, some short T2 tissues appear dark in conventional MR images because the signal from these tissues has decayed to nearly zero before the center of k-space is acquired. Because of the ability of directly imaging short T2 tissues, ultrashort echo time technique has been widely studied in recent years. An overwhelming majority of the studies were carried out at high fields, while many low- field scanner systems are still used in developing countries. To investigate the effects of the delay between analog-to-digital converter sampling and the readout gradient, the TE of the second echo used to calculate the R2 * map, and the undersampling ratio on the results of three-dimensional (3D) ultrashort echo time imaging at a low field, we implemented a 3D ultrashort echo time sequence on a 0. 35T scanner. Different parameters were used and the reconstructed images and R2 * maps were compared. Images reconstructed with slightly varying delays appeared quite different. Different contrast between short and long T2 tissues were found in R2 * maps calculated with different echoes. The result of undersampling study indicated that excessive undersampling could cause unwanted blurring, making it difficult to better visualize the short T2 tissues in the R2 * map. The results suggested that cautions should be taken in the choice of these parameters in 3D ultrashort echo time imaging. Short T2 tissues can be visualized with appropriate imaging parameters at this low field. PMID:27079094

  6. A California statewide three-dimensional seismic velocity model from both absolute and differential times

    USGS Publications Warehouse

    Lin, G.; Thurber, C.H.; Zhang, H.; Hauksson, E.; Shearer, P.M.; Waldhauser, F.; Brocher, T.M.; Hardebeck, J.

    2010-01-01

    We obtain a seismic velocity model of the California crust and uppermost mantle using a regional-scale double-difference tomography algorithm. We begin by using absolute arrival-time picks to solve for a coarse three-dimensional (3D) P velocity (VP) model with a uniform 30 km horizontal node spacing, which we then use as the starting model for a finer-scale inversion using double-difference tomography applied to absolute and differential pick times. For computational reasons, we split the state into 5 subregions with a grid spacing of 10 to 20 km and assemble our final statewide VP model by stitching together these local models. We also solve for a statewide S-wave model using S picks from both the Southern California Seismic Network and USArray, assuming a starting model based on the VP results and a VP=VS ratio of 1.732. Our new model has improved areal coverage compared with previous models, extending 570 km in the SW-NE directionand 1320 km in the NW-SE direction. It also extends to greater depth due to the inclusion of substantial data at large epicentral distances. Our VP model generally agrees with previous separate regional models for northern and southern California, but we also observe some new features, such as high-velocity anomalies at shallow depths in the Klamath Mountains and Mount Shasta area, somewhat slow velocities in the northern Coast Ranges, and slow anomalies beneath the Sierra Nevada at midcrustal and greater depths. This model can be applied to a variety of regional-scale studies in California, such as developing a unified statewide earthquake location catalog and performing regional waveform modeling.

  7. Clustering criterion for inertial particles in two-dimensional time-periodic and three-dimensional steady flows.

    PubMed

    Sapsis, Themistoklis; Haller, George

    2010-03-01

    We derive an analytic condition that predicts the exact location of inertial particle clustering in three-dimensional steady or two-dimensional time-periodic flows. The particles turn out to cluster on attracting inertial Lagrangian coherent structures that are smooth deformations of invariant tori. We illustrate our results on three-dimensional steady flows, including the Hill's spherical vortex and the Arnold-Beltrami-Childress flow, as well as on a two-dimensional time and space periodic flow that models a meandering jet in a channel.

  8. TEMPEST: A three-dimensional time-dependent computer program for hydrothermal analysis: Volume 1, Numerical methods and input instructions

    SciTech Connect

    Trent, D.S.; Eyler, L.L.; Budden, M.J.

    1983-09-01

    This document describes the numerical methods, current capabilities, and the use of the TEMPEST (Version L, MOD 2) computer program. TEMPEST is a transient, three-dimensional, hydrothermal computer program that is designed to analyze a broad range of coupled fluid dynamic and heat transfer systems of particular interest to the Fast Breeder Reactor thermal-hydraulic design community. The full three-dimensional, time-dependent equations of motion, continuity, and heat transport are solved for either laminar or turbulent fluid flow, including heat diffusion and generation in both solid and liquid materials. 10 refs., 22 figs., 2 tabs.

  9. Image system for three dimensional, 360 DEGREE, time sequence surface mapping of moving objects

    DOEpatents

    Lu, Shin-Yee

    1998-01-01

    A three-dimensional motion camera system comprises a light projector placed between two synchronous video cameras all focused on an object-of-interest. The light projector shines a sharp pattern of vertical lines (Ronchi ruling) on the object-of-interest that appear to be bent differently to each camera by virtue of the surface shape of the object-of-interest and the relative geometry of the cameras, light projector and object-of-interest Each video frame is captured in a computer memory and analyzed. Since the relative geometry is known and the system pre-calibrated, the unknown three-dimensional shape of the object-of-interest can be solved for by matching the intersections of the projected light lines with orthogonal epipolar lines corresponding to horizontal rows in the video camera frames. A surface reconstruction is made and displayed on a monitor screen. For 360.degree. all around coverage of theobject-of-interest, two additional sets of light projectors and corresponding cameras are distributed about 120.degree. apart from one another.

  10. Image system for three dimensional, 360{degree}, time sequence surface mapping of moving objects

    DOEpatents

    Lu, S.Y.

    1998-12-22

    A three-dimensional motion camera system comprises a light projector placed between two synchronous video cameras all focused on an object-of-interest. The light projector shines a sharp pattern of vertical lines (Ronchi ruling) on the object-of-interest that appear to be bent differently to each camera by virtue of the surface shape of the object-of-interest and the relative geometry of the cameras, light projector and object-of-interest. Each video frame is captured in a computer memory and analyzed. Since the relative geometry is known and the system pre-calibrated, the unknown three-dimensional shape of the object-of-interest can be solved for by matching the intersections of the projected light lines with orthogonal epipolar lines corresponding to horizontal rows in the video camera frames. A surface reconstruction is made and displayed on a monitor screen. For 360{degree} all around coverage of the object-of-interest, two additional sets of light projectors and corresponding cameras are distributed about 120{degree} apart from one another. 20 figs.

  11. Importance of three-dimensional grids and time-dependent factors for applications of earthquake forecasting models to subduction environments

    NASA Astrophysics Data System (ADS)

    Chan, Chung-Han

    2016-09-01

    This study provides some new insights into earthquake forecasting models that are applied to regions with subduction systems, including the depth component for forecasting grids and time-dependent factors. To demonstrate the importance of depth component, a forecasting approach, which incorporates three-dimensional grids, is compared with an approach with two-dimensional cells. Through application to the two subduction regions, Ryukyu and Kanto, it is shown that the approaches with three-dimensional grids always demonstrate a better forecasting ability. I thus confirm the importance of depth dependency for forecasting, especially for applications to a subduction environment or a region with non-vertical seismogenic structures. In addition, this study discusses the role of time-dependent factors for forecasting models and concludes that time dependency only becomes crucial during the period with significant seismicity rate change that follows a large earthquake.

  12. Three dimensional time lapse imaging of live cell mitochondria with photothermal optical lock-in optical coherence microscopy (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Sison, Miguel; Chakrabortty, Sabyasachi; Extermann, Jerome; Nahas, Amir; Pache, Christophe; Weil, Tanja; Lasser, Theo

    2016-03-01

    The photothermal optical lock-in optical coherence microscope (poli-OCM) introduced molecular specificity to OCM imaging, which is conventionally, a label-free technique. Here we achieve three-dimensional live cell and mitochondria specific imaging using ~4nm protein-functionalized gold nanoparticles (AuNPs). These nanoparticles do not photobleach and we demonstrate they're suitability for long-term time lapse imaging. We compare the accuracy of labelling with these AuNPs using classical fluorescence confocal imaging with a standard mitochondria specific marker. Furthermore, time lapse poli-OCM imaging every 5 minutes over 1.5 hours period was achieved, revealing the ability for three-dimensional monitoring of mitochondria dynamics.

  13. Three-Dimensional, Finite-Difference, Time-Domain Modeling of Local Volcano Infrasound Radiation Using GPU

    NASA Astrophysics Data System (ADS)

    Kim, K.; Lees, J. M.

    2013-12-01

    Since volcano infrasound is a direct measure of atmospheric pressure fluctuation near open-vent activity, it can provide important constraints on eruption source parameters including the volume of gas released and eruption velocity. Local infrasound data (<15 Km) have been used to quantify and characterize acoustic sources of volcanic eruptions since they are relatively less affected by atmospheric velocity structures in the near field. The interaction of volcano infrasound sources and complex topography near the volcanic edifice, however, has not been fully explored. Infrasound observations from world-wide volcanoes and two-dimensional numerical modeling of infrasound radiation in the vicinity of the crater suggest a strong distortion of the wavefield by local topography [Kim and Lees, GRL, 2011]. To get a complete picture of these effects, however, full three-dimensional modeling is required. We have developed a new, accelerated, 3D finite-difference time-domain program using GPU (Grpahic Processing Units) to simulate local infrasound propagation near volcanoes, while taking into account complex topography, local wind distortion, and atmospheric sound velocity structures. While CPU-based 3D FDTD method requires a prohibitive amount of computational resources, GPU-based algorithms significantly reduce the computational time of infrasound modeling, making parallel processing practical even on a desktop computer. In these simulations we provide a comprehensive solution of volcano infrasound radiation assuming different acoustic sources and real volcano topography. We illustrate the interaction of local vent topography and difference acoustic sources and how they combine to affect the infrasound wavefield. By removing topographic effects from local infrasound observation we can begin to quantitatively model acoustic sources and finally establish the partitioning of energy, at the vent, between the acoustic and seismic wavefields.

  14. Three-dimensional transient model for time-domain free-carrier absorption measurement of excess carriers in silicon wafers

    SciTech Connect

    Ren, Shengdong; Huang, Qiuping; Li, Bincheng

    2013-12-28

    A three-dimensional transient model for time-domain (modulated) free-carrier absorption (FCA) measurement was developed to describe the transport dynamics of photo-generated excess carriers in silicon (Si) wafers. With the developed transient model, numerical simulations were performed to investigate the dependences of the waveforms of the transient FCA signals on the electronic transport parameters of Si wafers and the geometric parameters of the FCA experiment. Experimental waveforms of FCA signals of both n- and p-type Si wafers with resistivity ranging 1–38 Ω·cm were then fitted to the three-dimensional transient model to extract simultaneously and unambiguously the transport parameters of Si wafers, namely, the carrier lifetime, the carrier diffusion coefficient, and the front surface recombination velocity via multi-parameter fitting. A basic agreement between the extracted parameter values and the literature values was obtained.

  15. Three-dimensional, time-dependent, MHD model of a solar flare-generated interplanetary shock wave

    NASA Technical Reports Server (NTRS)

    Dryer, M.; Wu, S. T.; Han, S. M.

    1986-01-01

    A three-dimensional time-dependent MHD model of the propagation of an interplanetary shock wave into an ambient three-dimensional heliospheric solar wind is initialized with a peak velocity of 1000 km/s at the center of a right circular cone of 18 deg included angle at 18 solar radii. Differences from a previous 2-1/2 simulation (Wu et al., 1983; Gislason et al., 1984; Dryer et al., 1984) include diminuation of the solar peak velocity and concentration of the peak density at each radius. The IMF magnitude starts with high-latitude peaks, and helical-like IMF rotation is noted due to a large-amplitude nonlinear Alfven wave in the shocked plasma.

  16. Three-dimensional time-dependent computer modeling of the electrothermal atomizers for analytical spectrometry

    NASA Astrophysics Data System (ADS)

    Tsivilskiy, I. V.; Nagulin, K. Yu.; Gilmutdinov, A. Kh.

    2016-02-01

    A full three-dimensional nonstationary numerical model of graphite electrothermal atomizers of various types is developed. The model is based on solution of a heat equation within solid walls of the atomizer with a radiative heat transfer and numerical solution of a full set of Navier-Stokes equations with an energy equation for a gas. Governing equations for the behavior of a discrete phase, i.e., atomic particles suspended in a gas (including gas-phase processes of evaporation and condensation), are derived from the formal equations molecular kinetics by numerical solution of the Hertz-Langmuir equation. The following atomizers test the model: a Varian standard heated electrothermal vaporizer (ETV), a Perkin Elmer standard THGA transversely heated graphite tube with integrated platform (THGA), and the original double-stage tube-helix atomizer (DSTHA). The experimental verification of computer calculations is carried out by a method of shadow spectral visualization of the spatial distributions of atomic and molecular vapors in an analytical space of an atomizer.

  17. Facial three-dimensional morphometry.

    PubMed

    Ferrario, V F; Sforza, C; Poggio, C E; Serrao, G

    1996-01-01

    Three-dimensional facial morphometry was investigated in a sample of 40 men and 40 women, with a new noninvasive computerized method. Subjects ranged in age between 19 and 32 years, had sound dentitions, and no craniocervical disorders. For each subject, 16 cutaneous facial landmarks were automatically collected by a system consisting of two infrared camera coupled device (CCD) cameras, real time hardware for the recognition of markers, and software for the three-dimensional reconstruction of landmarks' x, y, z coordinates. From these landmarks, 15 linear and 10 angular measurements, and four linear distance ratios were computed and averaged for sex. For all angular values, both samples showed a narrow variability and no significant gender differences were demonstrated. Conversely, all the linear measurements were significantly higher in men than in women. The highest intersample variability was observed for the measurements of facial height (prevalent vertical dimension), and the lowest for the measurements of facial depth (prevalent horizontal dimension). The proportions of upper and lower face height relative to the anterior face height showed a significant sex difference. Mean values were in good agreement with literature data collected with traditional methods. The described method allowed the direct and noninvasive calculation of three-dimensional linear and angular measurements that would be usefully applied in clinics as a supplement to the classic x-ray cephalometric analyses. PMID:8540488

  18. Alternating-direction implicit numerical solution of the time-dependent, three-dimensional, single fluid, resistive magnetohydrodynamic equations

    SciTech Connect

    Finan, C.H. III

    1980-12-01

    Resistive magnetohydrodynamics (MHD) is described by a set of eight coupled, nonlinear, three-dimensional, time-dependent, partial differential equations. A computer code, IMP (Implicit MHD Program), has been developed to solve these equations numerically by the method of finite differences on an Eulerian mesh. In this model, the equations are expressed in orthogonal curvilinear coordinates, making the code applicable to a variety of coordinate systems. The Douglas-Gunn algorithm for Alternating-Direction Implicit (ADI) temporal advancement is used to avoid the limitations in timestep size imposed by explicit methods. The equations are solved simultaneously to avoid syncronization errors.

  19. Long-Time Numerical Integration of the Three-Dimensional Wave Equation in the Vicinity of a Moving Source

    NASA Technical Reports Server (NTRS)

    Ryabenkii, V. S.; Turchaninov, V. I.; Tsynkov, S. V.

    1999-01-01

    We propose a family of algorithms for solving numerically a Cauchy problem for the three-dimensional wave equation. The sources that drive the equation (i.e., the right-hand side) are compactly supported in space for any given time; they, however, may actually move in space with a subsonic speed. The solution is calculated inside a finite domain (e.g., sphere) that also moves with a subsonic speed and always contains the support of the right-hand side. The algorithms employ a standard consistent and stable explicit finite-difference scheme for the wave equation. They allow one to calculate tile solution for arbitrarily long time intervals without error accumulation and with the fixed non-growing amount of tile CPU time and memory required for advancing one time step. The algorithms are inherently three-dimensional; they rely on the presence of lacunae in the solutions of the wave equation in oddly dimensional spaces. The methodology presented in the paper is, in fact, a building block for constructing the nonlocal highly accurate unsteady artificial boundary conditions to be used for the numerical simulation of waves propagating with finite speed over unbounded domains.

  20. Three dimensional time-gated tracking of non-blinking quantum dots in live cells

    DOE PAGESBeta

    DeVore, Matthew S.; Werner, James H.; Goodwin, Peter M.; Keller, Aaron M.; Hollingsworth, Jennifer A.; Wilson, Bridget S.; Cleyrat, Cedric; Lidke, Diane S.; Ghosh, Yagnaseni; Stewart, Michael H.; et al

    2015-03-12

    Single particle tracking has provided a wealth of information about biophysical processes such as motor protein transport and diffusion in cell membranes. However, motion out of the plane of the microscope or blinking of the fluorescent probe used as a label generally limits observation times to several seconds. Here, we overcome these limitations by using novel non-blinking quantum dots as probes and employing a custom 3D tracking microscope to actively follow motion in three dimensions (3D) in live cells. As a result, signal-to-noise is improved in the cellular milieu through the use of pulsed excitation and time-gated detection.

  1. Three dimensional time-gated tracking of non-blinking quantum dots in live cells

    PubMed Central

    DeVore, Matthew S.; Stich, Dominik G.; Keller, Aaron M.; Ghosh, Yagnaseni; Goodwin, Peter M.; Phipps, Mary E.; Stewart, Michael H.; Cleyrat, Cédric; Wilson, Bridget S.; Lidke, Diane S.; Hollingsworth, Jennifer A.; Werner, James H.

    2015-01-01

    Single particle tracking has provided a wealth of information about biophysical processes such as motor protein transport and diffusion in cell membranes. However, motion out of the plane of the microscope or blinking of the fluorescent probe used as a label generally limits observation times to several seconds. Here, we overcome these limitations by using novel non-blinking quantum dots as probes and employing a custom 3D tracking microscope to actively follow motion in three dimensions (3D) in live cells. Signal-to-noise is improved in the cellular milieu through the use of pulsed excitation and time-gated detection. PMID:25932286

  2. Three dimensional time-gated tracking of non-blinking quantum dots in live cells

    SciTech Connect

    DeVore, Matthew S.; Werner, James H.; Goodwin, Peter M.; Keller, Aaron M.; Hollingsworth, Jennifer A.; Wilson, Bridget S.; Cleyrat, Cedric; Lidke, Diane S.; Ghosh, Yagnaseni; Stewart, Michael H.; Stich, Dominik G.; Phipps, Mary E.

    2015-12-03

    Single particle tracking has provided a wealth of information about biophysical processes such as motor protein transport and diffusion in cell membranes. However, motion out of the plane of the microscope or blinking of the fluorescent probe used as a label generally limits observation times to several seconds. Here, we overcome these limitations by using novel non-blinking quantum dots as probes and employing a custom 3D tracking microscope to actively follow motion in three dimensions (3D) in live cells. As a result, signal-to-noise is improved in the cellular milieu through the use of pulsed excitation and time-gated detection.

  3. Three dimensional time-gated tracking of non-blinking quantum dots in live cells

    NASA Astrophysics Data System (ADS)

    DeVore, Matthew S.; Stich, Dominik G.; Keller, Aaron M.; Ghosh, Yagna; Goodwin, Peter M.; Phipps, Mary E.; Stewart, Michael H.; Cleyrat, Cédric; Wilson, Bridget S.; Lidke, Diane S.; Hollingsworth, Jennifer A.; Werner, James H.

    2015-03-01

    Single particle tracking has provided a wealth of information about biophysical processes such as motor protein transport and diffusion in cell membranes. However, motion out of the plane of the microscope or blinking of the fluorescent probe used as a label generally limits observation times to several seconds. Here, we overcome these limitations by using novel non-blinking quantum dots as probes and employing a custom 3D tracking microscope to actively follow motion in three dimensions (3D) in live cells. Signal-to-noise is improved in the cellular milieu through the use of pulsed excitation and time-gated detection.

  4. Coherent optical three-dimensional spectrum-correlation processing of wave signals based on space-time integration.

    PubMed

    Ezhov, Vasily

    2012-11-20

    The architectures of classical analog coherent optical (ACO) spectrum analyzers and correlators are not designed to process the wave signal as a whole, i.e., simultaneously in three dimensions. In this paper, the theory of ACO three-dimensional direct spectrum-correlation processing of spatial-temporal optical replicas (copies) of wave signals is discussed. In the single-stage and two-stage ACO systems, the spatial power spectrum and spatial correlation function of the wave signal (envelope) are obtained on the basis of space-time integration. The geometry of the final compressed signal in the output plane of either optical system allows one to evaluate the angle of wave arrival. The wave signal to be processed can theoretically have any form (due to autocorrelation properties of the systems) and an unlimited duration (due to time integration of wave energy and possibility of electronic subtraction of the intermediate bias terms of the time integration).

  5. Parallel solution of the three-dimensional time-dependent Ginzburg- Landau equation

    SciTech Connect

    Galbreath, N.; Gropp, W.; Gunter, D.; Leaf, G.; Levine, D.

    1996-08-01

    The recent discovery of superconductivity in a class of copper-oxide compounds (the cuprate superconductors) at liquid nitrogen temperatures has generated a renewed interest in the magnetic properties of type-II superconductors. In our work, we are investigating these properties using the phenomenological time- dependent Ginzburg-Landau equation. This paper describes the parallelization of this equation.

  6. Three-dimensional structure of inner core anisotropy from PKP differential travel times and waveforms

    NASA Astrophysics Data System (ADS)

    Song, X.

    2003-12-01

    Discussion with Prof. Don Anderson was one of the most inspiring and stimulating experiences in my science career when we were searching for evidence for inner core anisotropy a little over ten years ago. At the time, the hypothesis of inner core anisotropy was not fully accepted. Now models of 3D inner core anisotropy have been proposed. Recent studies suggest that the uppermost inner core is nearly isotropic and western and eastern hemispheres of the inner core are different in both velocity and anisotropy. Yet differential PKP travel times at near antipodal distances show convincingly that significant anisotropy exists in the bulk of the inner core at both hemispheres. Recently Xinlei Sun and I assemble differential PKP travel-time measurements at distances of 145 to 180o, obtained by us and others over the years, to investigate the 3-D structure of the inner core anisotropy. These differential times reduces the biases from earthquake mislocations and heterogeneous upper mantle. We invert for 3D inner core anisotropy by dividing the inner core into four layers in radius and six sectors in longitudes. The top 100 km of the inner core is assumed to be isotropic. Our inversion suggests that at depth of 100-500 km below the inner core boundary, the quasi-eastern hemisphere (40 to 160oE) is nearly isotropic (less than 1% of anisotropy) while the western hemisphere is strongly anisotropic (3 to 5% anisotropy). However, at depth of 500-900 km, both hemispheres are anisotropic (about 3% anisotropy). At the innermost 300 km of the inner core, the form of anisotropy seems distinctly different. One of the most dramatic manifestations of changes in anisotropy is the observation of seismic triplication of inner core waves; a type of multipathing effect due to heterogeneity that Don challenged to think about even in the early days. The best example is the seismic triplication observed from South Sandwich Islands earthquakes recorded at stations in Canada and Alaska.

  7. Three-dimensional Euler time accurate simulations of fan rotor-stator interactions

    NASA Technical Reports Server (NTRS)

    Boretti, A. A.

    1990-01-01

    A numerical method useful to describe unsteady 3-D flow fields within turbomachinery stages is presented. The method solves the compressible, time dependent, Euler conservation equations with a finite volume, flux splitting, total variation diminishing, approximately factored, implicit scheme. Multiblock composite gridding is used to partition the flow field into a specified arrangement of blocks with static and dynamic interfaces. The code is optimized to take full advantage of the processing power and speed of the Cray Y/MP supercomputer. The method is applied to the computation of the flow field within a single stage, axial flow fan, thus reproducing the unsteady 3-D rotor-stator interaction.

  8. Three Dimensional Energetics of Left Ventricle Flows Using Time-Resolved DPIV

    NASA Astrophysics Data System (ADS)

    Pierrakos, Olga; Vlachos, Pavlos

    2006-11-01

    Left ventricular (LV) flows in the human heart are very complex and in the presence of unhealthy or prosthetic heart valves (HV), the complexity of the flow is further increased. Yet to date, no study has documented the complex 3D hemodynamic characteristics and energetics of LV flows. We present high sampling frequency Time Resolved DPIV results obtained in a flexible, transparent LV documenting the evolution of eddies and turbulence. The purpose is to characterize the energetics of the LV flow field in the presence of four orientations of the most commonly implanted mechanical bileaflet HV and a porcine valve. By decomposing the energy scales of the flow field, the ultimate goal is to quantify the total energy losses associated with vortex ring formation and turbulence dissipation. The energies associated to vortex ring formation give a measure of the energy trapped within the structure while estimations of the turbulence dissipation rate (TDR) give a measure of the energy dissipated at the smaller scales. For the first time in cardiovascular applications, an LES-based PIV method, which overcomes the limitations of conventional TDR estimation methods that assume homogeneous isotropic turbulence, was employed. We observed that energy lost at the larger scales (vortex ring) is much higher than the energy lost at the smaller scales due to turbulence dissipation.

  9. Three-dimensional, paper-based microfluidic devices containing internal timers for running time-based diagnostic assays.

    PubMed

    Phillips, Scott T; Thom, Nicole K

    2013-01-01

    This chapter describes a method for fabricating three-dimensional (3D), paper-based microfluidic devices that contain internal timers for running quantitative, time-based assays. The method involves patterning microfluidic channels into paper, and cutting double-sided adhesive tape into defined patterns. Patterned paper and tape are assembled layer by layer to create 3D microfluidic devices that are capable of distributing microliter volumes of a sample into multiple regions on a device for conducting multiple assays simultaneously. Paraffin wax is incorporated into defined regions within the device to provide control over the distribution rate of a sample, and food coloring is included in defined regions within the device to provide an unambiguous readout when the sample has reached the bottom of the device (this latter feature is the endpoint of the timer).

  10. A three-dimensional time-dependent theory for helix traveling wave tubes in beam-wave interaction

    NASA Astrophysics Data System (ADS)

    Peng, Wei-Feng; Hu, Yu-Lu; Yang, Zhong-Hai; Li, Jian-Qing; Lu, Qi-Ru; Li, Bin

    2011-02-01

    This paper presents a three-dimensional time-dependent nonlinear theory of helix traveling wave tubes for beam-wave interaction. The radio frequency electromagnetic fields are represented as the superposition of azimuthally symmetric waves in a vacuum sheath helix. Coupling impedance is introduced to the electromagnetic field equations' stimulating sources, which makes the theory easier and more flexible to realize. The space charge fields are calculated by electron beam space-charge waves expressed as the superposition solutions of Helmholtz equations. The focusing forces due to either a solenoidal field or a periodic permanent magnetic field is also included. The dynamical equations of electrons are Lorentz equations associating with electromagnetic fields, focusing fields and space-charge fields. The numerically simulated results of a tube are presented.

  11. Frequency and time domain three-dimensional inversion of electromagnetic data for a grounded-wire source

    NASA Astrophysics Data System (ADS)

    Sasaki, Yutaka; Yi, Myeong-Jong; Choi, Jihyang; Son, Jeong-Sul

    2015-01-01

    We present frequency- and time-domain three-dimensional (3-D) inversion approaches that can be applied to transient electromagnetic (TEM) data from a grounded-wire source using a PC. In the direct time-domain approach, the forward solution and sensitivity were obtained in the frequency domain using a finite-difference technique, and the frequency response was then Fourier-transformed using a digital filter technique. In the frequency-domain approach, TEM data were Fourier-transformed using a smooth-spectrum inversion method, and the recovered frequency response was then inverted. The synthetic examples show that for the time derivative of magnetic field, frequency-domain inversion of TEM data performs almost as well as time-domain inversion, with a significant reduction in computational time. In our synthetic studies, we also compared the resolution capabilities of the ground and airborne TEM and controlled-source audio-frequency magnetotelluric (CSAMT) data resulting from a common grounded wire. An airborne TEM survey at 200-m elevation achieved a resolution for buried conductors almost comparable to that of the ground TEM method. It is also shown that the inversion of CSAMT data was able to detect a 3-D resistivity structure better than the TEM inversion, suggesting an advantage of electric-field measurements over magnetic-field-only measurements.

  12. Prediction system of the 1-AU arrival times of CME-associated interplanetary shocks using three-dimensional simulations

    NASA Astrophysics Data System (ADS)

    den, Mitsue; Amo, Hiroyoshi; Sugihara, Kohta; Takei, Toshifumi; Ogawa, Tomoya; Tanaka, Takashi; Watari, Shinichi

    We describe prediction system of the 1-AU arrival times of interplanetary shock waves associated with coromal mass ejections (CMEs). The system is based on modeling of the shock propagation using a three-dimensional adaptive mesh refinement (AMR) code. Once a CME is observed by LASCO/SOHO, firstly ambient solar wind is obtained by numerical simulation, which reproduces the solar wind parameters at that time observed by ACE spacecraft. Then we input the expansion speed and occurrence position data of that CME as initial condtions for an CME model, and 3D simulation of the CME and the shock propagation is perfomed until the shock wave passes the 1-AU. Input the parameters, execution of simulation and output of the result are available on Web, so a person who is not familiar with operation of computer or simulations or is not a researcher can use this system to predict the shock passage time. Simulated CME and shock evolution is visuallized at the same time with simulation and snap shots appear on the web automatically, so that user can follow the propagation. This system is expected to be useful for forecasters of space weather. We will describe the system and simulation model in detail.

  13. Three-dimensional visual stimulator

    NASA Astrophysics Data System (ADS)

    Takeda, Tsunehiro; Fukui, Yukio; Hashimoto, Keizo; Hiruma, Nobuyuki

    1995-02-01

    We describe a newly developed three-dimensional visual stimulator (TVS) that can change independently the directions, distances, sizes, luminance, and varieties of two sets of targets for both eyes. It consists of liquid crystal projectors (LCP's) that generate the flexible images of targets, Badal otometers that change target distances without changing the visual angles, and relay-lens systems that change target directions. A special control program is developed for real-time control of six motors and two LCP's in the TVS together with a three-dimensional optometer III that simultaneously measures eye movement, accommodation, pupil diameter, and head movement. distance, 0 to -20 D; direction, 16 horizontally and 15 vertically; size, 0-2 deg visual angle; and luminance, 10-2-10 2 cd/m2. The target images are refreshed at 60 Hz and speeds with which the target makes a smooth change (ramp stimuli) are size, 10 deg/s. A simple application demonstrates the performance.

  14. Technique for designing and evaluating probe caps used in optical topography of infants using a real head model based on three dimensional magnetic resonance images

    NASA Astrophysics Data System (ADS)

    Hirabayashi, Yukiko; Sato, Hiroki; Uchida-Ota, Mariko; Nakai, Akio; Maki, Atsushi

    2008-06-01

    We have developed an effective technique for aiding the design and evaluating the performance of the probe caps used to perform optical topography (OT) on infants. To design and evaluate a probe cap, it is necessary to determine the measurement positions for conducting OT on the brain surface of subjects. One technique for determining these positions on the brain surface is to find their three-dimensional (3D) coordinates using a 3D magnetic space digitizer, which consists of a 3D magnetic source and a 3D magnetic sensor. The problem with this technique is that it takes a long time to determine all the measurement points on the subject's head and it is difficult to use with infants. It is a particular problem with infants who cannot support their own heads. Therefore, we have developed a real model of an infant subject's head based on 3D magnetic resonance (MR) images. The model is made from an optical-curable resin using 3D computer-aided-format coordinate data taken from 3D MR image-format coordinate data. We have determined the measurement positions on the surface of the model corresponding to a scalp using a 3D magnetic space digitizer and displayed the positions on a 3D MR image of the infant's brain. Using this technique, we then determined the actual 72 measurement positions located over the entire brain surface area for use with our new whole-head probe cap for neonates and infants. This method is useful for evaluating the performance of and designing probe caps.

  15. Two- and three-dimensional accuracy of dental impression materials: effects of storage time and moisture contamination.

    PubMed

    Chandran, Deepa T; Jagger, Daryll C; Jagger, Robert G; Barbour, Michele E

    2010-01-01

    Dental impression materials are used to create an inverse replica of the dental hard and soft tissues, and are used in processes such as the fabrication of crowns and bridges. The accuracy and dimensional stability of impression materials are of paramount importance to the accuracy of fit of the resultant prosthesis. Conventional methods for assessing the dimensional stability of impression materials are two-dimensional (2D), and assess shrinkage or expansion between selected fixed points on the impression. In this study, dimensional changes in four impression materials were assessed using an established 2D and an experimental three-dimensional (3D) technique. The former involved measurement of the distance between reference points on the impression; the latter a contact scanning method for producing a computer map of the impression surface showing localised expansion, contraction and warpage. Dimensional changes were assessed as a function of storage times and moisture contamination comparable to that found in clinical situations. It was evident that dimensional changes observed using the 3D technique were not always apparent using the 2D technique, and that the former offers certain advantages in terms of assessing dimensional accuracy and predictability of impression methods. There are, however, drawbacks associated with 3D techniques such as the more time-consuming nature of the data acquisition and difficulty in statistically analysing the data.

  16. Super multi-view three-dimensional display through spatial-spectrum time-multiplexing of planar aligned OLED microdisplays.

    PubMed

    Teng, Dongdong; Liu, Lilin; Wang, Biao

    2014-12-15

    Existing super multi-view (SMV) technologies depend on ultra-high resolution two-dimensional (2D) display panel or large number of 2D display panels to obtain dense sub-viewing-zones for constructing more natural three-dimensional (3D) display by pure spatial-multiplexing. Through gating the spatial-spectrum of each OLED microdisplay, the present work proposes a new SMV technology combining time- and spatial-multiplexing based on planar-aligned OLED microdisplays. The inherent light emission characteristics of OLED, i.e. large divergence angle, guarantees a homogeneous light intensity distribution on the spectrum plane, which is a necessary condition for successful time multiplexing. The developed system bears with low requirements on the number of 2D display panels. The factors influencing the lateral display resolution limit are discussed and the optimum value is deduced. Experimentally, a prototype system with 60 sub-viewing-zones is demonstrated by 12 OLED microdisplays. The horizontal interval between adjacent sub-viewing-zones is 1.6mm.

  17. TIME EVOLUTION OF THE THREE-DIMENSIONAL ACCRETION FLOWS: EFFECTS OF THE ADIABATIC INDEX AND OUTER BOUNDARY CONDITION

    SciTech Connect

    Janiuk, Agnieszka; Sznajder, Maciej; Moscibrodzka, Monika; Proga, Daniel

    2009-11-10

    We study a slightly rotating accretion flow onto a black hole, using the fully three-dimensional (3D) numerical simulations. We consider hydrodynamics of an inviscid flow, assuming a spherically symmetric density distribution at the outer boundary and a small, latitude-dependent angular momentum. We investigate the role of the adiabatic index and gas temperature, and the flow behavior due to non-axisymmetric effects. Our 3D simulations confirm axisymmetric results: the material that has too much angular momentum to be accreted forms a thick torus near the equator, and the mass accretion rate is lower than the Bondi rate. In our previous study of the 3D accretion flows, for gamma = 5/3, we found that the inner torus precessed, even for axisymmetric conditions at large radii. The present study shows that the inner torus precesses also for other values of the adiabatic index: gamma = 4/3, 1.2, and 1.01. However, the time for the precession to set increases with decreasing gamma. In particular, for gamma = 1.01, we find that depending on the outer boundary conditions, the torus may shrink substantially due to the strong inflow of the non-rotating matter, and the precession will have insufficient time to develop. On the other hand, if the torus is supplied by the continuous inflow of the rotating material from the outer radii, its inner parts will eventually tilt and precess, as was for the larger gamma's.

  18. Analytical solitonlike solutions and the dynamics of ultracold Fermi gases in a time-dependent three-dimensional harmonic potential.

    PubMed

    Wang, Ying; Luo, Guosen; Zhou, Yu; Hang, Chao

    2015-09-01

    We present a theoretical study of solitonlike solutions and their dynamics of ultracold superfluid Fermi gases trapped in a time-dependent three-dimensional (3D) harmonic potential with gain or loss. The 3D analytical solitonlike solutions are obtained without introducing any additional integrability constraints used elsewhere. The propagation of both bright- and dark-soliton-like solutions is investigated. We show that the amplitudes of dark-soliton-like solutions exhibit periodic oscillation, whereas those of the bright-soliton-like ones do not show such behavior. Moreover, we highlight that the oscillation periods of dark-soliton-like solutions predicted by our approach are matched very well with those observed in a recent experiment carried out by Yefsah et al. [T. Yefsah, A. T. Sommer, M. J. H. Ku, L. W. Cheuk, W. Ji, W. S. Bakr, and M. W. Zwierlein, Nature (London) 499, 426 (2013)NATUAS0028-083610.1038/nature12338] in both Bose-Einstein condensation and unitarity regimes.

  19. A novel backlight unit for volume-holographic optical elements-based time-multiplexed three-dimensional displays

    NASA Astrophysics Data System (ADS)

    Kim, Byung-Mok; Hwang, Yong-Seok; Kim, Eun-Soo

    2015-11-01

    In volume-holographic optical elements (VHOEs)-based time-sequential three-dimensional (3-D) displays, two reference beams generated from a backlight unit (BLU) illuminate VHOEs, and from which object beams satisfying the Brag condition are then diffracted. These beams form a pair of alternating light fields for stereo 3-D view. Since this system operates based on diffraction optics, its performance highly depends on the degrees of collimation and uniformity of the reference beams. Thus, a new BLU system to generate uniformly-collimated reference beams for the VHOEs-based 3-D display is proposed by combined use of a light-guide-plate (LGP) grooved with an array of angle-variant flat-top prisms, and two LED light sources attached with reflection-type beam collimators. Simulation results with LightTools 7.1 show that the average full-width at half maximum (FWHM), backshift ratio and intensity uniformity of the LGP output beam of the proposed system have been significantly reduced down to 2.8° and 0.4%, and increased up to 90.9%, respectively, from the values of 51.8°, 26.5% and 24.5% of the conventional system. They represent 18.5-, 66.3- and 3.7-fold improvements of those values in the proposed system, respectively. These successful results confirm the feasibility of the proposed system in the practical VHOEs-based 3-D display.

  20. Three-dimensional laser microvision.

    PubMed

    Shimotahira, H; Iizuka, K; Chu, S C; Wah, C; Costen, F; Yoshikuni, Y

    2001-04-10

    A three-dimensional (3-D) optical imaging system offering high resolution in all three dimensions, requiring minimum manipulation and capable of real-time operation, is presented. The system derives its capabilities from use of the superstructure grating laser source in the implementation of a laser step frequency radar for depth information acquisition. A synthetic aperture radar technique was also used to further enhance its lateral resolution as well as extend the depth of focus. High-speed operation was made possible by a dual computer system consisting of a host and a remote microcomputer supported by a dual-channel Small Computer System Interface parallel data transfer system. The system is capable of operating near real time. The 3-D display of a tunneling diode, a microwave integrated circuit, and a see-through image taken by the system operating near real time are included. The depth resolution is 40 mum; lateral resolution with a synthetic aperture approach is a fraction of a micrometer and that without it is approximately 10 mum. PMID:18357177

  1. Effect of short-term exposure to stereoscopic three-dimensional flight displays on real-world depth perception

    NASA Technical Reports Server (NTRS)

    Busquets, Anthony M.; Parrish, Russell V.; Williams, Steven P.

    1991-01-01

    High-fidelity color pictorial displays that incorporate depth cues in the display elements are currently available. Depth cuing applied to advanced head-down flight display concepts potentially enhances the pilot's situational awareness and improves task performance. Depth cues provided by stereopsis exhibit constraints that must be fully understood so depth cuing enhancements can be adequately realized and exploited. A fundamental issue (the goal of this investigation) is whether the use of head-down stereoscopic displays in flight applications degrade the real-world depth perception of pilots using such displays. Stereoacuity tests are used in this study as the measure of interest. Eight pilots flew repeated simulated landing approaches using both nonstereo and stereo 3-D head-down pathway-in-the-sky displays. At this decision height of each approach (where the pilot changes to an out-the-window view to obtain real-world visual references) the pilots changed to a stereoacuity test that used real objects. Statistical analysis of stereoacuity measures (data for a control condition of no exposure to any electronic flight display compared with data for changes from nonstereo and from stereo displays) reveals no significant differences for any of the conditions. Therefore, changing from short-term exposure to a head-down stereo display has no more effect on real-world relative depth perception than does changing from a nonstereo display. However, depth perception effects based on sized and distance judgements and on long-term exposure remain issues to be investigated.

  2. Residence Times and Pathway Analysis Using a Coupled Three-Dimensional Variably Saturated Groundwater Flow and Land Surface Model

    NASA Astrophysics Data System (ADS)

    Kollet, S. J.; Maxwell, R. M.

    2007-12-01

    The analysis of residence times and pathways of solutes in the subsurface is important in the characterization of biogeochemical processes and contaminant transport. Recent theoretical and experimental studies have shown power law (fractal) residence time distributions because of the fractal character of the topography. The theoretical studies focused on a steady-state analysis of the flow field utilizing an undulating water table boundary condition that follows the topography. However, processes of the vadose zone including root water uptake and evaporation have been neglected until this work. In this study, the three-dimensional variably saturated groundwater flow model ParFlow, coupled to a land surface model, is used to study the influence of processes of the vadose zone on pathways and residence time distributions. A small catchment is simulated incorporating topography; land and soil cover information; and one year of realistic atmospheric forcing. Transient Lagrangian transport simulations of a conservative tracer are performed, also including dispersion (i.e. heterogeneity), to develop spectral transforms of the arrival time distributions. The resulting power spectra show power law behavior over a wide range of scales. While the spectral scaling exponent (SSP) decreases with increasing heterogeneity, the influence of the vadose zone appears to cause an increase in the SSP. Additionally, the effect of explicit representation of subsurface heterogeneity and spatial model resolution on the scaling behavior is studied. This work was conducted under the auspices of the U. S. Department of Energy by the University of California, Lawrence Livermore National Laboratory (LLNL) under contract W-7405-Eng-48. This project was funded by the Laboratory Directed Research and Development Program at LLNL.

  3. Issues in measure-preserving three dimensional flow integrators: Self-adjointness, reversibility, and non-uniform time stepping

    SciTech Connect

    Finn, John M.

    2015-03-01

    Properties of integration schemes for solenoidal fields in three dimensions are studied, with a focus on integrating magnetic field lines in a plasma using adaptive time stepping. It is shown that implicit midpoint (IM) and a scheme we call three-dimensional leapfrog (LF) can do a good job (in the sense of preserving KAM tori) of integrating fields that are reversible, or (for LF) have a 'special divergence-free' property. We review the notion of a self-adjoint scheme, showing that such schemes are at least second order accurate and can always be formed by composing an arbitrary scheme with its adjoint. We also review the concept of reversibility, showing that a reversible but not exactly volume-preserving scheme can lead to a fractal invariant measure in a chaotic region, although this property may not often be observable. We also show numerical results indicating that the IM and LF schemes can fail to preserve KAM tori when the reversibility property (and the SDF property for LF) of the field is broken. We discuss extensions to measure preserving flows, the integration of magnetic field lines in a plasma and the integration of rays for several plasma waves. The main new result of this paper relates to non-uniform time stepping for volume-preserving flows. We investigate two potential schemes, both based on the general method of Ref. [11], in which the flow is integrated in split time steps, each Hamiltonian in two dimensions. The first scheme is an extension of the method of extended phase space, a well-proven method of symplectic integration with non-uniform time steps. This method is found not to work, and an explanation is given. The second method investigated is a method based on transformation to canonical variables for the two split-step Hamiltonian systems. This method, which is related to the method of non-canonical generating functions of Ref. [35], appears to work very well.

  4. Transport and residence times of tropospheric aerosols inferred from a global three-dimensional simulation of Pb-210

    NASA Technical Reports Server (NTRS)

    Balkanski, Yves J.; Jacob, Daniel J.; Gardner, Geraldine M.; Graustein, William C.; Turekian, Karl K.

    1993-01-01

    A global three-dimensional model is used to investigate the transport and tropospheric residence time of Pb-210, an aerosol tracer produced in the atmosphere by radioactive decay of Rn-222 emitted from soils. The model uses meteorological input with 4 deg x 5 deg horizontal resolution and 4-hour temporal resolution from the Goddard Institute for Space Studies general circulation model (GCM). It computes aerosol scavenging by convective precipitation as part of the wet convective mass transport operator in order to capture the coupling between vertical transport and rainout. Scavenging in convective precipitation accounts for 74% of the global Pb-210 sink in the model; scavenging in large-scale precipitation accounts for 12%, and scavenging in dry deposition accounts for 14%. The model captures 63% of the variance of yearly mean Pb-210 concentrations measured at 85 sites around the world with negligible mean bias, lending support to the computation of aerosol scavenging. There are, however, a number of regional and seasonal discrepancies that reflect in part anomalies in GCM precipitation. Computed residence times with respect to deposition for Pb-210 aerosol in the tropospheric column are about 5 days at southern midlatitudes and 10-15 days in the tropics; values at northern midlatitudes vary from about 5 days in winter to 10 days in summer. The residence time of Pb-210 produced in the lowest 0.5 km of atmosphere is on average four times shorter than that of Pb-210 produced in the upper atmosphere. Both model and observations indicate a weaker decrease of Pb-210 concentrations between the continental mixed layer and the free troposphere than is observed for total aerosol concentrations; an explanation is that Rn-222 is transported to high altitudes in wet convective updrafts, while aerosols and soluble precursors of aerosols are scavenged by precipitation in the updrafts. Thus Pb-210 is not simply a tracer of aerosols produced in the continental boundary layer, but

  5. Issues in measure-preserving three dimensional flow integrators: Self-adjointness, reversibility, and non-uniform time stepping

    DOE PAGESBeta

    Finn, John M.

    2015-03-01

    Properties of integration schemes for solenoidal fields in three dimensions are studied, with a focus on integrating magnetic field lines in a plasma using adaptive time stepping. It is shown that implicit midpoint (IM) and a scheme we call three-dimensional leapfrog (LF) can do a good job (in the sense of preserving KAM tori) of integrating fields that are reversible, or (for LF) have a 'special divergence-free' property. We review the notion of a self-adjoint scheme, showing that such schemes are at least second order accurate and can always be formed by composing an arbitrary scheme with its adjoint. Wemore » also review the concept of reversibility, showing that a reversible but not exactly volume-preserving scheme can lead to a fractal invariant measure in a chaotic region, although this property may not often be observable. We also show numerical results indicating that the IM and LF schemes can fail to preserve KAM tori when the reversibility property (and the SDF property for LF) of the field is broken. We discuss extensions to measure preserving flows, the integration of magnetic field lines in a plasma and the integration of rays for several plasma waves. The main new result of this paper relates to non-uniform time stepping for volume-preserving flows. We investigate two potential schemes, both based on the general method of Ref. [11], in which the flow is integrated in split time steps, each Hamiltonian in two dimensions. The first scheme is an extension of the method of extended phase space, a well-proven method of symplectic integration with non-uniform time steps. This method is found not to work, and an explanation is given. The second method investigated is a method based on transformation to canonical variables for the two split-step Hamiltonian systems. This method, which is related to the method of non-canonical generating functions of Ref. [35], appears to work very well.« less

  6. Issues in measure-preserving three dimensional flow integrators: Self-adjointness, reversibility, and non-uniform time stepping

    SciTech Connect

    Finn, John M.

    2015-03-15

    Properties of integration schemes for solenoidal fields in three dimensions are studied, with a focus on integrating magnetic field lines in a plasma using adaptive time stepping. It is shown that implicit midpoint (IM) and a scheme we call three-dimensional leapfrog (LF) can do a good job (in the sense of preserving KAM tori) of integrating fields that are reversible, or (for LF) have a “special divergence-free” (SDF) property. We review the notion of a self-adjoint scheme, showing that such schemes are at least second order accurate and can always be formed by composing an arbitrary scheme with its adjoint. We also review the concept of reversibility, showing that a reversible but not exactly volume-preserving scheme can lead to a fractal invariant measure in a chaotic region, although this property may not often be observable. We also show numerical results indicating that the IM and LF schemes can fail to preserve KAM tori when the reversibility property (and the SDF property for LF) of the field is broken. We discuss extensions to measure preserving flows, the integration of magnetic field lines in a plasma and the integration of rays for several plasma waves. The main new result of this paper relates to non-uniform time stepping for volume-preserving flows. We investigate two potential schemes, both based on the general method of Feng and Shang [Numer. Math. 71, 451 (1995)], in which the flow is integrated in split time steps, each Hamiltonian in two dimensions. The first scheme is an extension of the method of extended phase space, a well-proven method of symplectic integration with non-uniform time steps. This method is found not to work, and an explanation is given. The second method investigated is a method based on transformation to canonical variables for the two split-step Hamiltonian systems. This method, which is related to the method of non-canonical generating functions of Richardson and Finn [Plasma Phys. Controlled Fusion 54, 014004 (2012

  7. Three-dimensional accurate detection of lung emphysema in rats using ultra-short and zero echo time MRI.

    PubMed

    Bianchi, Andrea; Tibiletti, Marta; Kjørstad, Åsmund; Birk, Gerald; Schad, Lothar R; Stierstorfer, Birgit; Rasche, Volker; Stiller, Detlef

    2015-11-01

    Emphysema is a life-threatening pathology that causes irreversible destruction of alveolar walls. In vivo imaging techniques play a fundamental role in the early non-invasive pre-clinical and clinical detection and longitudinal follow-up of this pathology. In the present study, we aimed to evaluate the feasibility of using high resolution radial three-dimensional (3D) zero echo time (ZTE) and 3D ultra-short echo time (UTE) MRI to accurately detect lung pathomorphological changes in a rodent model of emphysema.Porcine pancreas elastase (PPE) was intratracheally administered to the rats to produce the emphysematous changes. 3D ZTE MRI, low and high definition 3D UTE MRI and micro-computed tomography images were acquired 4 weeks after the PPE challenge. Signal-to-noise ratios (SNRs) were measured in PPE-treated and control rats. T2* values were computed from low definition 3D UTE MRI. Histomorphometric measurements were made after euthanizing the animals. Both ZTE and UTE MR images showed a significant decrease in the SNR measured in PPE-treated lungs compared with controls, due to the pathomorphological changes taking place in the challenged lungs. A significant decrease in T2* values in PPE-challenged animals compared with controls was measured using UTE MRI. Histomorphometric measurements showed a significant increase in the mean linear intercept in PPE-treated lungs. UTE yielded significantly higher SNR compared with ZTE (14% and 30% higher in PPE-treated and non-PPE-treated lungs, respectively).This study showed that optimized 3D radial UTE and ZTE MRI can provide lung images of excellent quality, with high isotropic spatial resolution (400 µm) and SNR in parenchymal tissue (>25) and negligible motion artifacts in freely breathing animals. These techniques were shown to be useful non-invasive instruments to accurately and reliably detect the pathomorphological alterations taking place in emphysematous lungs, without incurring the risks of cumulative radiation

  8. Three-dimensional magnetic resonance imaging overlay to assist with percutaneous transhepatic access at the time of cardiac catheterization.

    PubMed

    Whiteside, Wendy; Christensen, Jason; Zampi, Jeffrey D

    2015-01-01

    Multimodality image overlay is increasingly used for complex interventional procedures in the cardiac catheterization lab. We report a case in which three-dimensional magnetic resonance imaging (3D MRI) overlay onto live fluoroscopic imaging was utilized to safely obtain transhepatic access in a 12-year-old patient with prune belly syndrome, complex and distorted abdominal anatomy, and a vascular mass within the liver.

  9. [Real time 3D echocardiography

    NASA Technical Reports Server (NTRS)

    Bauer, F.; Shiota, T.; Thomas, J. D.

    2001-01-01

    Three-dimensional representation of the heart is an old concern. Usually, 3D reconstruction of the cardiac mass is made by successive acquisition of 2D sections, the spatial localisation and orientation of which require complex guiding systems. More recently, the concept of volumetric acquisition has been introduced. A matricial emitter-receiver probe complex with parallel data processing provides instantaneous of a pyramidal 64 degrees x 64 degrees volume. The image is restituted in real time and is composed of 3 planes (planes B and C) which can be displaced in all spatial directions at any time during acquisition. The flexibility of this system of acquisition allows volume and mass measurement with greater accuracy and reproducibility, limiting inter-observer variability. Free navigation of the planes of investigation allows reconstruction for qualitative and quantitative analysis of valvular heart disease and other pathologies. Although real time 3D echocardiography is ready for clinical usage, some improvements are still necessary to improve its conviviality. Then real time 3D echocardiography could be the essential tool for understanding, diagnosis and management of patients.

  10. [Real time 3D echocardiography].

    PubMed

    Bauer, F; Shiota, T; Thomas, J D

    2001-07-01

    Three-dimensional representation of the heart is an old concern. Usually, 3D reconstruction of the cardiac mass is made by successive acquisition of 2D sections, the spatial localisation and orientation of which require complex guiding systems. More recently, the concept of volumetric acquisition has been introduced. A matricial emitter-receiver probe complex with parallel data processing provides instantaneous of a pyramidal 64 degrees x 64 degrees volume. The image is restituted in real time and is composed of 3 planes (planes B and C) which can be displaced in all spatial directions at any time during acquisition. The flexibility of this system of acquisition allows volume and mass measurement with greater accuracy and reproducibility, limiting inter-observer variability. Free navigation of the planes of investigation allows reconstruction for qualitative and quantitative analysis of valvular heart disease and other pathologies. Although real time 3D echocardiography is ready for clinical usage, some improvements are still necessary to improve its conviviality. Then real time 3D echocardiography could be the essential tool for understanding, diagnosis and management of patients. PMID:11494630

  11. Time-lapse three-dimensional inversion of complex conductivity data using an active time constrained (ATC) approach

    USGS Publications Warehouse

    Karaoulis, M.; Revil, A.; Werkema, D.D.; Minsley, B.J.; Woodruff, W.F.; Kemna, A.

    2011-01-01

    Induced polarization (more precisely the magnitude and phase of impedance of the subsurface) is measured using a network of electrodes located at the ground surface or in boreholes. This method yields important information related to the distribution of permeability and contaminants in the shallow subsurface. We propose a new time-lapse 3-D modelling and inversion algorithm to image the evolution of complex conductivity over time. We discretize the subsurface using hexahedron cells. Each cell is assigned a complex resistivity or conductivity value. Using the finite-element approach, we model the in-phase and out-of-phase (quadrature) electrical potentials on the 3-D grid, which are then transformed into apparent complex resistivity. Inhomogeneous Dirichlet boundary conditions are used at the boundary of the domain. The calculation of the Jacobian matrix is based on the principles of reciprocity. The goal of time-lapse inversion is to determine the change in the complex resistivity of each cell of the spatial grid as a function of time. Each model along the time axis is called a 'reference space model'. This approach can be simplified into an inverse problem looking for the optimum of several reference space models using the approximation that the material properties vary linearly in time between two subsequent reference models. Regularizations in both space domain and time domain reduce inversion artefacts and improve the stability of the inversion problem. In addition, the use of the time-lapse equations allows the simultaneous inversion of data obtained at different times in just one inversion step (4-D inversion). The advantages of this new inversion algorithm are demonstrated on synthetic time-lapse data resulting from the simulation of a salt tracer test in a heterogeneous random material described by an anisotropic semi-variogram. ?? 2011 The Authors Geophysical Journal International ?? 2011 RAS.

  12. Three-dimensional viscoelastic time-domain finite-difference seismic modelling using the staggered Adams-Bashforth time integrator

    NASA Astrophysics Data System (ADS)

    Bohlen, Thomas; Wittkamp, Florian

    2016-03-01

    We analyse the performance of a higher order accurate staggered viscoelastic time-domain finite-difference method, in which the staggered Adams-Bashforth (ABS) third-order and fourth-order accurate time integrators are used for temporal discretization. ABS is a multistep method that uses previously calculated wavefields to increase the order of accuracy in time. The analysis shows that the numerical dispersion is much lower than that of the widely used second-order leapfrog method. Numerical dissipation is introduced by the ABS method which is significantly smaller for fourth-order than third-order accuracy. In 1-D and 3-D simulation experiments, we verify the convincing improvements of simulation accuracy of the fourth-order ABS method. In a realistic elastic 3-D scenario, the computing time reduces by a factor of approximately 2.4, whereas the memory requirements increase by approximately a factor of 2.2. The ABS method thus provides an alternative strategy to increase the simulation accuracy in time by investing computer memory instead of computing time.

  13. Three dimensional ultrasonic imaging

    SciTech Connect

    Thomas, G. H.; Benson, S.; Crawford, S.

    1993-03-01

    Ultrasonic nondestructive evaluation techniques interrogate components with high frequency acoustic energy. A transducer generates the acoustic energy and converts acoustic energy to electrical signals. The acoustic energy is reflected by abrupt changes in modulus and/or density which can be caused by a defect. Thus defects reflect the ultrasonic energy which is converted into electrical signals. Ultrasonic evaluation typically provides a two dimensional image of internal defects. These images are either planar views (C-scans) or cross-sectional views (B-scans). The planar view is generated by raster scanning an ultrasonic transducer over the component and capturing the amplitude of internal reflections. Depth information is generally ignored. The cross-sectional view is generated by scanning the transducer along a single line and capturing the amplitude and time of flight for each internal reflection. The amplitude and time of flight information is converted into an image of the cross section of the component where the scan was performed. By fusing the C-scan information with the B-scan information a three dimension image of the internal structure of the component can be produced. The three dimensional image can be manipulated by rotating and slicing to produce the optimal view of the internal structure. The high frequency ultrasonic energy requires a liquid coupling media and thus applications for imaging in liquid environments are well suited to ultrasonic techniques. Examples of potential ultrasonic imaging applications are: Inside liquid filled tanks, inside the human body, and underwater.

  14. Finite Difference Time Domain Analysis of Diffusion Equations with Nonuniform Grids for Time-Resolved Reflectance of an Optical Pulse in Three-Dimensional Scattering Medium

    NASA Astrophysics Data System (ADS)

    Tanifuji, Tadatoshi; Ichitsubo, Khota

    2005-11-01

    An integral form of diffusion equations and their finite difference time domain (FDTD) analysis have been formulated. The analysis is extended to FDTD analysis with nonuniform grids in three-dimensional (3-D) scattering medium. It has been confirmed that 600 time steps in calculation sequences of the time-resolved reflectance for 3-D medium 80 × 80 × 30 mm3 in volume is completed within 4 seconds by utilizing 23 and 43 mm3 nonuniform cubic grids, when a conventional personal computer with 3 GHz CPU clock is used. The conditions for keeping numerical accuracies comparable to those in 23 mm3 uniform grids are made clear. The proposed analysis greatly reduces time to run and memory space in 3-D scattering medium numerical analysis.

  15. Dynamic Three-Dimensional Echocardiography

    NASA Astrophysics Data System (ADS)

    Matsusaka, Katsuhiko; Doi, Motonori; Oshiro, Osamu; Chihara, Kunihiro

    2000-08-01

    Conventional three-dimensional (3D) ultrasound imaging equipment for diagnosis requires much time to reconstruct 3D images or fix the view point for observing the 3D image. Thus, it is inconvenient for cardiac diagnosis. In this paper, we propose a new dynamic 3D echocardiography system. The system produces 3D images in real-time and permits changes in view point. This system consists of ultrasound diagnostic equipment, a digitizer and a computer. B-mode images are projected to a virtual 3D space by referring to the position of the probe of the ultrasound diagnosis equipment. The position is obtained by the digitizer to which the ultrasound probe is attached. The 3D cardiac image is constructed from B-mode images obtained simultaneously in the cardiac cycle. To obtain the same moment of heartbeat in the cardiac cycle, this system uses the electrocardiography derived from the diagnosis equipment. The 3D images, which show various scenes of the stage of heartbeat action, are displayed sequentially. The doctor can observe 3D images cut in any plane by pushing a button of the digitizer and zooming with the keyboard. We evaluated our prototype system by observation of a mitral valve in motion.

  16. Parallel solver for the three-dimensional Cartesian-grid-based time-dependent Schrödinger equation and its applications in laser- H2+ interaction studies

    NASA Astrophysics Data System (ADS)

    Lee, Y.-M.; Wu, J.-S.; Jiang, T.-F.; Chen, Y.-S.

    2008-01-01

    A parallelized three-dimensional Cartesian-grid-based time-dependent Schrödinger equation (TDSE) solver for molecules with a single electron, assuming the motion of the nucleus is frozen, is presented in this paper. An explicit stagger-time algorithm is employed for time integration of the TDSE, in which the real and imaginary parts of the wave function are defined at alternate times, while a cell-centered finite-volume method is utilized for spatial discretization of the TDSE on Cartesian grids. The TDSE solver is then parallelized using the domain decomposition method on distributed memory machines by applying a multilevel graph-partitioning technique. The solver is validated using a H2+ molecule system, both by observing the total electron probability and total energy conservation without laser interaction, and by comparing the ionization rates with previous two-dimensional axisymmetric simulation results with an aligned incident laser pulse. The parallel efficiency of this TDSE solver is presented and discussed; the parallel efficiency can be as high as 75% using 128 processors. Finally, examples of the temporal evolution of the probability distribution of laser incidence onto a H2+ molecule at inter-nuclear distance of 9a.u. ( χ=0° and 90°) and the spectral intensities of harmonic generation at internuclear distance of 2a.u. ( χ=0° , 30°, 60°, and 90°) are presented to demonstrate the powerful capability of the current TDSE solver. Future possible extensions of the present method are also outlined at the end of this paper.

  17. Three-dimensional photovoltaics

    NASA Astrophysics Data System (ADS)

    Myers, Bryan; Bernardi, Marco; Grossman, Jeffrey C.

    2010-02-01

    The concept of three-dimensional (3D) photovoltaics is explored computationally using a genetic algorithm to optimize the energy production in a day for arbitrarily shaped 3D solar cells confined to a given area footprint and total volume. Our simulations demonstrate that the performance of 3D photovoltaic structures scales linearly with height, leading to volumetric energy conversion, and provides power fairly evenly throughout the day. Furthermore, we show that optimal 3D structures are not simple box-like shapes, and that design attributes such as reflectivity could be optimized using three-dimensionality.

  18. Three-dimensional photovoltaics

    NASA Astrophysics Data System (ADS)

    Myers, Bryan; Bernardi, Marco; Grossman, Jeffrey C.

    2010-03-01

    The concept of three-dimensional (3D) photovoltaics is explored computationally using a genetic algorithm to optimize the energy production in a day for arbitrarily shaped 3D solar cells confined to a given area footprint and total volume. Our simulations demonstrate that the performance of 3D photovoltaic structures scales linearly with height, leading to volumetric energy conversion, and provides power fairly evenly throughout the day. Furthermore, we show that optimal 3D shapes are not simple box-like shapes, and that design attributes such as reflectivity can be optimized in new ways using three-dimensionality.

  19. Study on three-dimensional face recognition with continuous-wave time-of-flight range cameras

    NASA Astrophysics Data System (ADS)

    Ebers, Olga; Ebers, Tatjana; Plaue, Matthias; Radüntz, Thea; Bärwolff, Günter; Schwandt, Hartmut

    2011-06-01

    For a number of different security and industrial applications, there is the need for reliable person identification methods. Among these methods, face recognition has a number of advantages such as being noninvasive and potentially covert. Other advantages of conventional two-dimensional face recognition, in particular, are its low data capture duration and its low cost. However, the recent introduction of fast and comparatively inexpensive time-of-flight cameras for the recording of 2.5D range data in real time calls for a closer look at three-dimentional face recognition in this context. One major disadvantage, however, is the low quality of the data acquired with this type of camera. In this paper, we investigate the feasibility of face recognition systems based on such range images.

  20. High speed three-dimensional laser scanner with real time processing

    NASA Technical Reports Server (NTRS)

    Lavelle, Joseph P. (Inventor); Schuet, Stefan R. (Inventor)

    2008-01-01

    A laser scanner computes a range from a laser line to an imaging sensor. The laser line illuminates a detail within an area covered by the imaging sensor, the area having a first dimension and a second dimension. The detail has a dimension perpendicular to the area. A traverse moves a laser emitter coupled to the imaging sensor, at a height above the area. The laser emitter is positioned at an offset along the scan direction with respect to the imaging sensor, and is oriented at a depression angle with respect to the area. The laser emitter projects the laser line along the second dimension of the area at a position where a image frame is acquired. The imaging sensor is sensitive to laser reflections from the detail produced by the laser line. The imaging sensor images the laser reflections from the detail to generate the image frame. A computer having a pipeline structure is connected to the imaging sensor for reception of the image frame, and for computing the range to the detail using height, depression angle and/or offset. The computer displays the range to the area and detail thereon covered by the image frame.

  1. Self-consistent calculation of nuclear photoabsorption cross sections: Finite amplitude method with Skyrme functionals in the three-dimensional real space

    NASA Astrophysics Data System (ADS)

    Inakura, Tsunenori; Nakatsukasa, Takashi; Yabana, Kazuhiro

    2009-10-01

    The finite amplitude method (FAM), which we have recently proposed [T. Nakatsukasa, T. Inakura, and K. Yabana, Phys. Rev. C 76, 024318 (2007)], significantly simplifies the fully self-consistent calculation of the random-phase approximation (RPA). This article presents a computational scheme of FAM suitable for systematic investigation and shows its performance for realistic Skyrme energy functionals. We adopt the mixed representation in which the forward and backward RPA amplitudes are represented by index of hole orbitals and of the spatial grid points for the three-dimensional real space. We solve a linear algebraic problem with a sparse non-Hermitian matrix, using an iterative method. We show results of the dipole response for selected spherical and deformed nuclei. The calculated peak energies of the giant dipole resonance well agree with experiments for heavy nuclei. However, they are systematically underestimated for light nuclei. We also discuss the width of the giant dipole resonance in the fully self-consistent RPA calculation.

  2. Three dimensional finite difference time domain modeling of Schumann resonances on Earth and other planets of the solar system

    NASA Astrophysics Data System (ADS)

    Yang, Heng

    2007-12-01

    Resonance properties of the Earth-ionosphere cavity were predicted by W. O. Schumann in 1952. Since then observations of electromagnetic signals in the frequency range 1-500 Hz have become a powerful tool for variety of remote sensing applications, which in recent years included studies of thunderstorm related transient luminous events in the middle atmosphere and related lightning discharges. In this thesis, a three dimensional Finite Difference Time Domain (FDTD) model is developed to study the propagation of the extremely low frequency (ELF) waves in the Earth-ionosphere cavity and in similar cavities on other celestial bodies of the Solar System. A comparison of the results from this FDTD model with a set of classical eigen-frequency (fn) and quality factor ( Qn) solutions for laterally uniform spherically symmetric Earth-ionosphere cavity and with recent observations of Schumann resonance (SR) during solar proton events (SPEs) and X-ray bursts is provided. The FDTD fn and Qn solutions for the uniform cavity appear to be in excellent agreement (within several %) with well-known experimental results documented in the literature. The related analysis indicates that the frequency of the first SR mode decreases during SPEs and increases during X-ray bursts by a fraction of a Hz, in agreement with physical arguments presented in previously published literature and with observations. The FDTD model is extended to include the effects of the geomagnetic field on SR parameters. A higher penetration height of SR electric and magnetic components is found with the presence of the geomagnetic field. In a realistic cavity, the conductivity distribution is not laterally uniform and spherically symmetric, but varies with local time and seasons reflecting related variations in the effects of solar radiation on the conductivity of the lower ionosphere. The global lightning activity in the three main areas (Africa, South-East Asia, and South America) also has diurnal and seasonal

  3. Real-time analysis keratometer

    NASA Technical Reports Server (NTRS)

    Adachi, Iwao P. (Inventor); Adachi, Yoshifumi (Inventor); Frazer, Robert E. (Inventor)

    1987-01-01

    A computer assisted keratometer in which a fiducial line pattern reticle illuminated by CW or pulsed laser light is projected on a corneal surface through lenses, a prismoidal beamsplitter quarterwave plate, and objective optics. The reticle surface is curved as a conjugate of an ideal corneal curvature. The fiducial image reflected from the cornea undergoes a polarization shift through the quarterwave plate and beamsplitter whereby the projected and reflected beams are separated and directed orthogonally. The reflected beam fiducial pattern forms a moire pattern with a replica of the first recticle. This moire pattern contains transverse aberration due to differences in curvature between the cornea and the ideal corneal curvature. The moire pattern is analyzed in real time by computer which displays either the CW moire pattern or a pulsed mode analysis of the transverse aberration of the cornea under observation, in real time. With the eye focused on a plurality of fixation points in succession, a survey of the entire corneal topography is made and a contour map or three dimensional plot of the cornea can be made as a computer readout in addition to corneal radius and refractive power analysis.

  4. Monitoring groundwater-surface water interaction using time-series and time-frequency analysis of transient three-dimensional electrical resistivity changes

    USGS Publications Warehouse

    Johnson, Timothy C.; Slater, Lee D.; Ntarlagiannis, Dimitris; Day-Lewis, Frederick D.; Elwaseif, Mehrez

    2012-01-01

    Time-lapse resistivity imaging is increasingly used to monitor hydrologic processes. Compared to conventional hydrologic measurements, surface time-lapse resistivity provides superior spatial coverage in two or three dimensions, potentially high-resolution information in time, and information in the absence of wells. However, interpretation of time-lapse electrical tomograms is complicated by the ever-increasing size and complexity of long-term, three-dimensional (3-D) time series conductivity data sets. Here we use 3-D surface time-lapse electrical imaging to monitor subsurface electrical conductivity variations associated with stage-driven groundwater-surface water interactions along a stretch of the Columbia River adjacent to the Hanford 300 near Richland, Washington, USA. We reduce the resulting 3-D conductivity time series using both time-series and time-frequency analyses to isolate a paleochannel causing enhanced groundwater-surface water interactions. Correlation analysis on the time-lapse imaging results concisely represents enhanced groundwater-surface water interactions within the paleochannel, and provides information concerning groundwater flow velocities. Time-frequency analysis using the Stockwell (S) transform provides additional information by identifying the stage periodicities driving groundwater-surface water interactions due to upstream dam operations, and identifying segments in time-frequency space when these interactions are most active. These results provide new insight into the distribution and timing of river water intrusion into the Hanford 300 Area, which has a governing influence on the behavior of a uranium plume left over from historical nuclear fuel processing operations.

  5. Timing of three-dimensional virtual treatment planning of orthognathic surgery: a prospective single-surgeon evaluation on 350 consecutive cases.

    PubMed

    Swennen, Gwen R J

    2014-11-01

    The purpose of this article is to evaluate the timing for three-dimensional (3D) virtual treatment planning of orthognathic surgery in the daily clinical routine. A total of 350 consecutive patients were included in this study. All patients were scanned following the standardized "Triple CBCT Scan Protocol" in centric relation. Integrated 3D virtual planning and actual surgery were performed by the same surgeon in all patients. Although clinically acceptable, still software improvements especially toward 3D virtual occlusal definition are mandatory to make 3D virtual planning of orthognathic surgery less time-consuming and more user-friendly to the clinician.

  6. Three-dimensional metamaterials

    DOEpatents

    Burckel, David Bruce

    2012-06-12

    A fabrication method is capable of creating canonical metamaterial structures arrayed in a three-dimensional geometry. The method uses a membrane suspended over a cavity with predefined pattern as a directional evaporation mask. Metallic and/or dielectric material can be evaporated at high vacuum through the patterned membrane to deposit resonator structures on the interior walls of the cavity, thereby providing a unit cell of micron-scale dimension. The method can produce volumetric metamaterial structures comprising layers of such unit cells of resonator structures.

  7. Three Dimensional Dirac Semimetals

    NASA Astrophysics Data System (ADS)

    Zaheer, Saad

    2014-03-01

    Dirac points on the Fermi surface of two dimensional graphene are responsible for its unique electronic behavior. One can ask whether any three dimensional materials support similar pseudorelativistic physics in their bulk electronic spectra. This possibility has been investigated theoretically and is now supported by two successful experimental demonstrations reported during the last year. In this talk, I will summarize the various ways in which Dirac semimetals can be realized in three dimensions with primary focus on a specific theory developed on the basis of representations of crystal spacegroups. A three dimensional Dirac (Weyl) semimetal can appear in the presence (absence) of inversion symmetry by tuning parameters to the phase boundary separating a bulk insulating and a topological insulating phase. More generally, we find that specific rules governing crystal symmetry representations of electrons with spin lead to robust Dirac points at high symmetry points in the Brillouin zone. Combining these rules with microscopic considerations identifies six candidate Dirac semimetals. Another method towards engineering Dirac semimetals involves combining crystal symmetry and band inversion. Several candidate materials have been proposed utilizing this mechanism and one of the candidates has been successfully demonstrated as a Dirac semimetal in two independent experiments. Work carried out in collaboration with: Julia A. Steinberg, Steve M. Young, J.C.Y. Teo, C.L. Kane, E.J. Mele and Andrew M. Rappe.

  8. Three Dimensional (3D) Printing: A Straightforward, User-Friendly Protocol to Convert Virtual Chemical Models to Real-Life Objects

    ERIC Educational Resources Information Center

    Rossi, Sergio; Benaglia, Maurizio; Brenna, Davide; Porta, Riccardo; Orlandi, Manuel

    2015-01-01

    A simple procedure to convert protein data bank files (.pdb) into a stereolithography file (.stl) using VMD software (Virtual Molecular Dynamic) is reported. This tutorial allows generating, with a very simple protocol, three-dimensional customized structures that can be printed by a low-cost 3D-printer, and used for teaching chemical education…

  9. Three-dimensional, two-species magnetohydrodynamic studies of the early time behaviors of the Combined Release and Radiation Effects Satellite G2 barium release

    SciTech Connect

    Xie, Lianghai Li, Lei; Wang, Jingdong; Zhang, Yiteng

    2014-04-15

    We present a three-dimensional, two-species (Ba{sup +} and H{sup +}) MHD model to study the early time behaviors of a barium release at about 1 R{sub E} like Combined Release and Radiation Effects Satellite G2, with emphasis placed on the three-dimensional evolution of the barium cloud and its effects on the ambient plasma environment. We find that the perturbations caused by the cloud are the combined results of the initial injection, the radial expansion, and the diamagnetic effect and propagate as fast MHD waves in the magnetosphere. In return, the transverse expansion and the cross-B motion of barium ions are constrained by the magnetic force, which lead to a field-aligned striation of ions and the decoupling of these ions from the neutrals. Our simulation shows the formation and collapse of the diamagnetic cavity in the barium cloud. The estimated time scale for the cavity evolution might be much shorter if photoionization time scale and field aligned expansion of barium ions are considered. In addition, our two species MHD simulation also finds the snowplow effect resulting from the momentum coupling between barium ions and background H{sup +}, which creates density hole and bumps in the background H{sup +} when barium ions expanding along the magnetic field lines.

  10. Real-time radiography

    SciTech Connect

    Bossi, R.H.; Oien, C.T.

    1981-02-26

    Real-time radiography is used for imaging both dynamic events and static objects. Fluorescent screens play an important role in converting radiation to light, which is then observed directly or intensified and detected. The radiographic parameters for real-time radiography are similar to conventional film radiography with special emphasis on statistics and magnification. Direct-viewing fluoroscopy uses the human eye as a detector of fluorescent screen light or the light from an intensifier. Remote-viewing systems replace the human observer with a television camera. The remote-viewing systems have many advantages over the direct-viewing conditions such as safety, image enhancement, and the capability to produce permanent records. This report reviews real-time imaging system parameters and components.

  11. Real time animation of space plasma phenomena

    NASA Technical Reports Server (NTRS)

    Jordan, K. F.; Greenstadt, E. W.

    1987-01-01

    In pursuit of real time animation of computer simulated space plasma phenomena, the code was rewritten for the Massively Parallel Processor (MPP). The program creates a dynamic representation of the global bowshock which is based on actual spacecraft data and designed for three dimensional graphic output. This output consists of time slice sequences which make up the frames of the animation. With the MPP, 16384, 512 or 4 frames can be calculated simultaneously depending upon which characteristic is being computed. The run time was greatly reduced which promotes the rapid sequence of images and makes real time animation a foreseeable goal. The addition of more complex phenomenology in the constructed computer images is now possible and work proceeds to generate these images.

  12. Deriving Sensitivity Kernels of Coda-Wave Travel Times to Velocity Changes Based on the Three-Dimensional Single Isotropic Scattering Model

    NASA Astrophysics Data System (ADS)

    Nakahara, Hisashi; Emoto, Kentaro

    2016-08-01

    Recently, coda-wave interferometry has been used to monitor temporal changes in subsurface structures. Seismic velocity changes have been detected by coda-wave interferometry in association with large earthquakes and volcanic eruptions. To constrain the spatial extent of the velocity changes, spatial homogeneity is often assumed. However, it is important to locate the region of the velocity changes correctly to understand physical mechanisms causing them. In this paper, we are concerned with the sensitivity kernels relating travel times of coda waves to velocity changes. In previous studies, sensitivity kernels have been formulated for two-dimensional single scattering and multiple scattering, three-dimensional multiple scattering, and diffusion. In this paper, we formulate and derive analytical expressions of the sensitivity kernels for three-dimensional single-scattering case. These sensitivity kernels show two peaks at both source and receiver locations, which is similar to the previous studies using different scattering models. The two peaks are more pronounced for later lapse time. We validate our formulation by comparing it with finite-difference simulations of acoustic wave propagation. Our formulation enables us to evaluate the sensitivity kernels analytically, which is particularly useful for the analysis of body waves from deeper earthquakes.

  13. Real-time sonography

    SciTech Connect

    Fleischey, A.C.; James, A.E. Jr.

    1984-01-01

    This textbook acquaints the reader with normal and pathologic anatomy as depicted on dynamic or real-time scanning. Chapters are organized by specialty, such as abdominal, urologic, or pediatric. The text is illustrated with still-frame images and line drawings. The drawings show important areas of interest and provide graphic notation as to where and in what orientation the scan was obtained.

  14. Three-dimensional dispersive hybrid implicit-explicit finite-difference time-domain method for simulations of graphene

    NASA Astrophysics Data System (ADS)

    Chen, Juan; Wang, Jianguo

    2016-10-01

    A dispersive hybrid implicit-explicit finite-difference time-domain (HIE-FDTD) method is presented in this paper. Surface conductivity of the graphene is incorporated into the HIE-FDTD method directly through an auxiliary difference equation. The time step size in proposed method has no relation with the fine spatial discretization, so it is very useful for the simulation of the graphene when it needs to be discretized across its thickness. The stability condition of this method is not only determined by the spatial cell sizes Δx and Δz, but also related with the surface conductivity of the graphene. The computational accuracy and efficiency of this method are demonstrated through numerical examples. The results show that with reasonable accuracy, the memory requirement and computation time of the dispersive HIE-FDTD method are both considerably reduced as compared with those of the conventional FDTD method and LOD-FDTD method.

  15. Three-dimensional change in the cervical spine in a cross-legged sitting position after a time lapse.

    PubMed

    Jung, Seo-Young; Choi, Bo-Ram

    2016-05-01

    [Purpose] The purpose of this study was to investigate the kinematic changes of the cervical spine during cross-legged sitting. [Subjects and Methods] In total, 19 healthy participants were recruited from among healthy students of Silla University. Each participant sat cross-legged with the right leg over the left and gazed at a target presented at 45° below the horizontal line of sight or at an object placed directly ahead, at 90° relative to horizontal for 10 minutes. [Results] With the 45° downward gaze, there was no significant difference in cervical angle between the 0-5-min and 5-10-min time periods. However, the angle in the sagittal plane increased with time, while the frontal and transverse plane angles decreased. With the 90° forward gaze, there was no significant difference in cervical angle between the 0-5-min and 5-10-min time periods. However, the frontal plane angle increased as time elapsed, while the sagittal and transverse plane angles increased between 0 and 5 min and decreased between 5 and 10 min. [Conclusion] Our results suggest that prolonged cross-legged sitting could produce malalignment of the cervical spine in three planes of motion. PMID:27313392

  16. Efficient compression of rearranged time-multiplexed elemental image arrays in MALT-based three-dimensional integral imaging

    NASA Astrophysics Data System (ADS)

    Kang, Ho-Hyun; Lee, Byung-Gook; Kim, Eun-Soo

    2011-06-01

    In this paper, an approach to efficiently compress the time-multiplexed EIAs picked up from the MALT-based integral imaging system is proposed. In this method, the time-multiplexed EIAs are rearranged by collecting the elemental images occupied at the same position in each EIA to enhance the similarity among the elemental images. Then, MPEG-4 is applied to these rearranged elemental images for compression. From the experimental results, it is shown that the average correlation quality ( ACQ) value representing a degree of similarity between the elemental images, and the resultant compression efficiency have been enhanced by 11.50% and 9.97%, respectively on the average for three kinds of test scenarios in the proposed method, compared to those of the conventional method. Good experimental results finally confirmed the feasibility of the proposed scheme.

  17. Three-dimensional time and frequency-domain theory of femtosecond x-ray pulse generation through Thomson Scattering

    SciTech Connect

    Brown, W J; Hartemann, F V

    2004-01-27

    The generation of high intensity, ultra-short x-ray pulses enables exciting new experimental capabilities, such as femtosecond pump-probe experiments used to temporally resolve material structural dynamics on atomic time scales. Thomson backscattering of a high intensity laser pulse with a bright relativistic electron bunch is a promising method for producing such high brightness x-ray pulses in the 10-100 keV range within a compact facility. While a variety of methods for producing sub-picosecond x-ray bursts by Thomson scattering exist, including compression of the electron bunch to sub-picosecond bunch lengths and/or colliding a sub-picosecond laser pulse in a side-on geometry to minimize the interaction time, a promising alternative approach to achieving this goal while maintaining ultra-high brightness is the production of a time correlated (or chirped) x-ray pulse in conjunction with pulse slicing or compression. We present the results of a complete analysis of this process using a recently developed 3-D time and frequency-domain code for analyzing the spatial, temporal, and spectral properties an x-ray beam produced by relativistic Thomson scattering. Based on the relativistic differential cross section, this code has the capability to calculate time and space dependent spectra of the x-ray photons produced from linear Thomson scattering for both bandwidth-limited and chirped incident laser pulses. Spectral broadening of the scattered x-ray pulse resulting from the incident laser bandwidth, laser focus, and the transverse and longitudinal phase space of the electron beam were examined. Simulations of chirped x-ray pulse production using both a chirped electron beam and a chirped laser pulse are presented. Required electron beam and laser parameters are summarized by investigating the effects of beam emittance, energy spread, and laser bandwidth on the scattered x-ray spectrum. It is shown that sufficient temporal correlation in the scattered x-ray spectrum

  18. Three-dimensional kinematics of the scapula and trunk, and associated scapular muscle timing in individuals with stroke.

    PubMed

    De Baets, Liesbet; Van Deun, Sara; Monari, Davide; Jaspers, Ellen

    2016-08-01

    Poor scapulothoracic control is a risk for developing shoulder pathology, but has received little attention so far in individuals with stroke (IwS). Trunk and scapular kinematics and surface muscle activity were measured in 15 healthy controls and 18 IwS during a low and high forward flexion (FF). Group-differences in trunk and scapular kinematics were assessed during low and high FF using a t-test (independent samples). Differences in muscle onset and offset time relative to movement start (both FF tasks) were determined using a mixed model taking into account the different groups and muscles. Recruitment patterns per group and task were described based on significant differences between muscles. In IwS, earlier lower trapezius and late infraspinatus offset were found during low FF, as well as a later onset and earlier offset of serratus anterior. For low FF, significantly more trunk axial rotation was found in IwS during both elevation and lowering. During high FF, IwS showed significantly less scapular posterior tilt during elevation and more scapular lateral rotation during lowering. IwS demonstrated adaptive muscle timing with earlier initiation and late inactivation of lower trapezius and infraspinatus, possibly to compensate for a late activation and early deactivation of the serratus anterior and to establish as such the correct pattern of scapulothoracic movement.

  19. Three-dimensional kinematics of the scapula and trunk, and associated scapular muscle timing in individuals with stroke.

    PubMed

    De Baets, Liesbet; Van Deun, Sara; Monari, Davide; Jaspers, Ellen

    2016-08-01

    Poor scapulothoracic control is a risk for developing shoulder pathology, but has received little attention so far in individuals with stroke (IwS). Trunk and scapular kinematics and surface muscle activity were measured in 15 healthy controls and 18 IwS during a low and high forward flexion (FF). Group-differences in trunk and scapular kinematics were assessed during low and high FF using a t-test (independent samples). Differences in muscle onset and offset time relative to movement start (both FF tasks) were determined using a mixed model taking into account the different groups and muscles. Recruitment patterns per group and task were described based on significant differences between muscles. In IwS, earlier lower trapezius and late infraspinatus offset were found during low FF, as well as a later onset and earlier offset of serratus anterior. For low FF, significantly more trunk axial rotation was found in IwS during both elevation and lowering. During high FF, IwS showed significantly less scapular posterior tilt during elevation and more scapular lateral rotation during lowering. IwS demonstrated adaptive muscle timing with earlier initiation and late inactivation of lower trapezius and infraspinatus, possibly to compensate for a late activation and early deactivation of the serratus anterior and to establish as such the correct pattern of scapulothoracic movement. PMID:27155342

  20. Three-dimensional, Time-Resolved, Intrafraction Motion Monitoring Throughout Stereotactic Liver Radiation Therapy on a Conventional Linear Accelerator

    SciTech Connect

    Worm, Esben S.; Høyer, Morten; Fledelius, Walter; Poulsen, Per R.

    2013-05-01

    Purpose: To investigate the time-resolved 3-dimensional (3D) internal motion throughout stereotactic body radiation therapy (SBRT) of tumors in the liver using standard x-ray imagers of a conventional linear accelerator. Methods and Materials: Ten patients with implanted gold markers received 11 treatment courses of 3-fraction SBRT in a stereotactic body-frame on a conventional linear accelerator. Two pretreatment and 1 posttreatment cone-beam computed tomography (CBCT) scans were acquired during each fraction. The CBCT projection images were used to estimate the internal 3D marker motion during CBCT acquisition with 11-Hz resolution by a monoscopic probability-based method. Throughout the treatment delivery by conformal or volumetric modulated arc fields, simultaneous MV portal imaging (8 Hz) and orthogonal kV imaging (5 Hz) were applied to determine the 3D marker motion using either MV/kV triangulation or the monoscopic method when marker segmentation was unachievable in either MV or kV images. The accuracy of monoscopic motion estimation was quantified by also applying monoscopic estimation as a test for all treatments during which MV/kV triangulation was possible. Results: Root-mean-square deviations between monoscopic estimations and triangulations were less than 1.0 mm. The mean 3D intrafraction and intrafield motion ranges during liver SBRT were 17.6 mm (range, 5.6-39.5 mm) and 11.3 mm (2.1-35.5mm), respectively. The risk of large intrafraction baseline shifts correlated with intrafield respiratory motion range. The mean 3D intrafractional marker displacement relative to the first CBCT was 3.4 mm (range, 0.7-14.5 mm). The 3D displacements exceeded 8.8 mm 10% of the time. Conclusions: Highly detailed time-resolved internal 3D motion was determined throughout liver SBRT using standard imaging equipment. Considerable intrafraction motion was observed. The demonstrated methods provide a widely available approach for motion monitoring that, combined with motion

  1. A three-dimensional simulation of transition and early turbulence in a time-developing mixing layer

    NASA Technical Reports Server (NTRS)

    Cain, A. B.; Reynolds, W. C.; Ferziger, J. H.

    1981-01-01

    The physics of the transition and early turbulence regimes in the time developing mixing layer was investigated. The sensitivity of the mixing layer to the disturbance field of the initial condition is considered. The growth of the momentum thickness, the mean velocity profile, the turbulence kinetic energy, the Reynolds stresses, the anisotropy tensor, and particle track pictures of computations are all examined in an effort to better understand the physics of these regimes. The amplitude, spectrum shape, and random phases of the initial disturbance field were varied. A scheme of generating discrete orthogonal function expansions on some nonuniform grids was developed. All cases address the early or near field of the mixing layer. The most significant result shows that the secondary instability of the mixing layer is produced by spanwise variations in the straining field of the primary vortex structures.

  2. On numerical model of time-dependent processes in three-dimensional porous heat-releasing objects

    NASA Astrophysics Data System (ADS)

    Lutsenko, Nickolay A.

    2016-10-01

    The gas flows in the gravity field through porous objects with heat-releasing sources are investigated when the self-regulation of the flow rate of the gas passing through the porous object takes place. Such objects can appear after various natural or man-made disasters (like the exploded unit of the Chernobyl NPP). The mathematical model and the original numerical method, based on a combination of explicit and implicit finite difference schemes, are developed for investigating the time-dependent processes in 3D porous energy-releasing objects. The advantage of the numerical model is its ability to describe unsteady processes under both natural convection and forced filtration. The gas cooling of 3D porous objects with different distribution of heat sources is studied using computational experiment.

  3. Time-dependent three-dimensional (latitude, longitude, altitude) response of the ionosphere to the 2009 SSW event

    NASA Astrophysics Data System (ADS)

    Azeem, S. I.; Crowley, G.; Reynolds, A.

    2013-12-01

    Recent studies have shown variations in the low and mid latitude ionosphere that are linked to Sudden Stratospheric Warming events. These studies suggest that during SSW events the equatorial electric fields vary in a quasi-deterministic way, producing vertical plasma drifts that deviate from climatological values more than expected. Although previous studies have provided important information on the ionospheric response to SSW events, they have been fairly localized. Therefore, broader observational capabilities and data are required that can unambiguously reveal the instantaneous global response of the ionosphere to SSW events. In this paper, we present four-dimensional (latitude, longitude, height and time) results of the Ionospheric Data Assimilation Four-Dimensional (IDA4D) algorithm to describe a global view of the ionospheric response to the 2009 SSW event. We use the IDA4D to assimilate ionosondes, ground-based GPS TEC, DORIS, CHAMP and GRACE occultation measurements for several days in January 2009 during the SSW event. IDA4D results show that at the peak of the 2009 SSW event, TEC values in the low latitudes were elevated in the morning hours while they were suppressed in the evening sector. The effects of enhanced dynamo forcing during the January 2009 SSW were also captured by the IDA4D showing an increased separation of the Appleton Anomaly peaks. The IDA4D results will be discussed in the context of horizontal, vertical and temporal evolution of ionospheric disturbances associated with the 2009 SSW event. The evolution of longitudinal, local time, and height (where applicable) variations of various plasma parameters (such as Ne, TEC, NmF2, hmF2, foF2) through the full 2009 SSW cycle (including genesis, onset, and recovery) will be presented.

  4. Parallel Monte Carlo transport modeling in the context of a time-dependent, three-dimensional multi-physics code

    SciTech Connect

    Procassini, R.J.

    1997-12-31

    The fine-scale, multi-space resolution that is envisioned for accurate simulations of complex weapons systems in three spatial dimensions implies flop-rate and memory-storage requirements that will only be obtained in the near future through the use of parallel computational techniques. Since the Monte Carlo transport models in these simulations usually stress both of these computational resources, they are prime candidates for parallelization. The MONACO Monte Carlo transport package, which is currently under development at LLNL, will utilize two types of parallelism within the context of a multi-physics design code: decomposition of the spatial domain across processors (spatial parallelism) and distribution of particles in a given spatial subdomain across additional processors (particle parallelism). This implementation of the package will utilize explicit data communication between domains (message passing). Such a parallel implementation of a Monte Carlo transport model will result in non-deterministic communication patterns. The communication of particles between subdomains during a Monte Carlo time step may require a significant level of effort to achieve a high parallel efficiency.

  5. Real-Time PCR

    NASA Astrophysics Data System (ADS)

    Evrard, A.; Boulle, N.; Lutfalla, G. S.

    Over the past few years there has been a considerable development of DNA amplification by polymerase chain reaction (PCR), and real-time PCR has now superseded conventional PCR techniques in many areas, e.g., the quantification of nucleic acids and genotyping. This new approach is based on the detection and quantification of a fluorescent signal proportional to the amount of amplicons generated by PCR. Real-time detection is achieved by coupling a thermocycler with a fluorimeter. This chapter discusses the general principles of quantitative real-time PCR, the different steps involved in implementing the technique, and some examples of applications in medicine. The polymerase chain reaction (PCR) provides a way of obtaining a large number of copies of a double-stranded DNA fragment of known sequence. This DNA amplification technique, developed in 1985 by K. Mullis (Cetus Corporation), saw a spectacular development over the space of a few years, revolutionising the methods used up to then in molecular biology. Indeed, PCR has many applications, such as the detection of small amounts of DNA, cloning, and quantitative analysis (assaying), each of which will be discussed further below.

  6. Enhancing Biological Analyses with Three Dimensional Field Asymmetric Ion Mobility, Low Field Drift Time Ion Mobility and Mass Spectrometry (µFAIMS/IMS-MS) Separations

    SciTech Connect

    Zhang, Xing; Ibrahim, Yehia M.; Chen, Tsung-Chi; Kyle, Jennifer E.; Norheim, Randolph V.; Monroe, Matthew E.; Smith, Richard D.; Baker, Erin Shammel

    2015-06-30

    We report the first evaluation of a platform coupling a high speed field asymmetric ion mobility spectrometry microchip (µFAIMS) with drift tube ion mobility and mass spectrometry (IMS-MS). The µFAIMS/IMS-MS platform was used to analyze biological samples and simultaneously acquire multidimensional information of detected features from the measured FAIMS compensation fields and IMS drift times, while also obtaining accurate ion masses. These separations thereby increase the overall separation power, resulting increased information content, and provide more complete characterization of more complex samples. The separation conditions were optimized for sensitivity and resolving power by the selection of gas compositions and pressures in the FAIMS and IMS separation stages. The resulting performance provided three dimensional separations, benefitting both broad complex mixture studies and targeted analyses by e.g. improving isomeric separations and allowing detection of species obscured by “chemical noise” and other interfering peaks.

  7. Some recent applications of XTRAN3S. [time marching finite difference code for solution of three-dimensional transonic small perturbation flow

    NASA Technical Reports Server (NTRS)

    Seidel, D. A.; Bennett, R. M.; Ricketts, R. H.

    1983-01-01

    A time-marching finite difference code, XTRAN3S, that solves the three-dimensional transonic small perturbation equation for flow over isolated wings has recently been developed. During initial applications of the program, problems were encountered in the prediction of unsteady forces. The use of a revised grid and force calculation scheme improved those predictions. Comparisons are made between predicted and experimental pressure data for a rectangular supercritical wing. Comparisons of steady and unsteady data at freestream Mach number = 0.700 show good agreement between calculated and experimental values. A comparison of steady data at freestream Mach number = 0.825 shows poor agreement between calculations and experiment. Program difficulties have been encountered with swept and tapered configurations.

  8. Scale-unambiguous relative pose estimation of space uncooperative targets based on the fusion of three-dimensional time-of-flight camera and monocular camera

    NASA Astrophysics Data System (ADS)

    Hao, Gangtao; Du, Xiaoping; Chen, Hang; Song, Jianjun; Gao, Tengfei

    2015-05-01

    An approach of scale-unambiguous relative pose estimation for space uncooperative targets based on the fusion of low resolution three-dimensional time-of-flight camera and monocular camera is proposed. No a priori knowledge about the targets is assumed. First, a modified range-intensity Markov random field model is presented to quickly reconstruct the range value for each feature point. Second, the scale-ambiguous relative pose estimation algorithm based on extended Kalman filter-unscented Kalman filter-particle filter combination filter is designed in vision simultaneous localization and mapping framework. Third, the overall scale factor estimation approach based on range-intensity fusion image, which takes the feature points' range reconstruction uncertainty as measurement noise, is proposed for the final scale-unambiguous pose estimation. Finally, some simulations demonstrate the validity and capability of the proposed approach.

  9. A staggered space-time discontinuous Galerkin method for the three-dimensional incompressible Navier-Stokes equations on unstructured tetrahedral meshes

    NASA Astrophysics Data System (ADS)

    Tavelli, Maurizio; Dumbser, Michael

    2016-08-01

    In this paper we propose a novel arbitrary high order accurate semi-implicit space-time discontinuous Galerkin method for the solution of the three-dimensional incompressible Navier-Stokes equations on staggered unstructured curved tetrahedral meshes. As is typical for space-time DG schemes, the discrete solution is represented in terms of space-time basis functions. This allows to achieve very high order of accuracy also in time, which is not easy to obtain for the incompressible Navier-Stokes equations. Similarly to staggered finite difference schemes, in our approach the discrete pressure is defined on the primary tetrahedral grid, while the discrete velocity is defined on a face-based staggered dual grid. While staggered meshes are state of the art in classical finite difference schemes for the incompressible Navier-Stokes equations, their use in high order DG schemes is still quite rare. A very simple and efficient Picard iteration is used in order to derive a space-time pressure correction algorithm that achieves also high order of accuracy in time and that avoids the direct solution of global nonlinear systems. Formal substitution of the discrete momentum equation on the dual grid into the discrete continuity equation on the primary grid yields a very sparse five-point block system for the scalar pressure, which is conveniently solved with a matrix-free GMRES algorithm. From numerical experiments we find that the linear system seems to be reasonably well conditioned, since all simulations shown in this paper could be run without the use of any preconditioner, even up to very high polynomial degrees. For a piecewise constant polynomial approximation in time and if pressure boundary conditions are specified at least in one point, the resulting system is, in addition, symmetric and positive definite. This allows us to use even faster iterative solvers, like the conjugate gradient method. The flexibility and accuracy of high order space-time DG methods on curved

  10. Three-Dimensional Visualization of Particle Tracks.

    ERIC Educational Resources Information Center

    Julian, Glenn M.

    1993-01-01

    Suggests ways to bring home to the introductory physics student some of the excitement of recent discoveries in particle physics. Describes particle detectors and encourages the use of the Standard Model along with real images of particle tracks to determine three-dimensional views of tracks. (MVL)

  11. Real time Faraday spectrometer

    DOEpatents

    Smith, Jr., Tommy E.; Struve, Kenneth W.; Colella, Nicholas J.

    1991-01-01

    This invention uses a dipole magnet to bend the path of a charged particle beam. As the deflected particles exit the magnet, they are spatially dispersed in the bend-plane of the magnet according to their respective momenta and pass to a plurality of chambers having Faraday probes positioned therein. Both the current and energy distribution of the particles is then determined by the non-intersecting Faraday probes located along the chambers. The Faraday probes are magnetically isolated from each other by thin metal walls of the chambers, effectively providing real time current-versus-energy particle measurements.

  12. Real time SAR processing

    NASA Technical Reports Server (NTRS)

    Premkumar, A. B.; Purviance, J. E.

    1990-01-01

    A simplified model for the SAR imaging problem is presented. The model is based on the geometry of the SAR system. Using this model an expression for the entire phase history of the received SAR signal is formulated. From the phase history, it is shown that the range and the azimuth coordinates for a point target image can be obtained by processing the phase information during the intrapulse and interpulse periods respectively. An architecture for a VLSI implementation for the SAR signal processor is presented which generates images in real time. The architecture uses a small number of chips, a new correlation processor, and an efficient azimuth correlation process.

  13. Real-Time Revolution?

    PubMed

    Berlin, Joey

    2016-03-01

    Austin Regional Clinic (ARC) physicians and officials know patient feedback is important, but getting patients to provide it can be a challenge. A pilot program of a new, real-time feedback system provided ARC patients a high-tech convenience previous attempts lacked and produced participation numbers dwarfing those past efforts. ARC's initial results with the system, in which patients answer five to seven questions on a computer tablet and can leave free-text comments, were so successful the clinic is already planning to expand it to all of its locations by the end of June.

  14. Self-intermediate scattering function of strongly interacting three-dimensional lattice gases: Time- and wave-vector-dependent tracer diffusion coefficient

    NASA Astrophysics Data System (ADS)

    Skarpalezos, Loukas; Argyrakis, Panos; Vikhrenko, Vyacheslav S.

    2014-05-01

    We investigate the self-intermediate scattering function (SISF) in a three-dimensional (3D) cubic lattice fluid (interacting lattice gas) with attractive nearest-neighbor interparticle interactions at a temperature slightly above the critical one by means of Monte Carlo simulations. A special representation of SISF as an exponent of the mean tracer diffusion coefficient multiplied by the geometrical factor and time is considered to highlight memory effects that are included in time and wave-vector dependence of the diffusion coefficient. An analytical expression for the diffusion coefficient is suggested to reproduce the simulation data. It is shown that the particles' mean-square displacement is equal to the time integral of the diffusion coefficient. We make a comparison with the previously considered 2D system on a square lattice. The main difference with the two-dimensional case is that the time dependence of particular characteristics of the tracer diffusion coefficient in the 3D case cannot be described by exponentially decreasing functions, but requires using stretched exponentials with rather small values of exponents, of the order of 0.2. The hydrodynamic values of the tracer diffusion coefficient (in the limit of large times and small wave vectors) defined through SIFS simulation results agree well with the results of its direct determination by the mean-square displacement of the particles in the entire range of concentrations and temperatures.

  15. On a class of unsteady three-dimensional Navier Stokes solutions relevant to rotating disc flows: Threshold amplitudes and finite time singularities

    NASA Technical Reports Server (NTRS)

    Hall, Philip; Balakumar, P.

    1990-01-01

    A class of exact steady and unsteady solutions of the Navier Stokes equations in cylindrical polar coordinates is given. The flows correspond to the motion induced by an infinite disc rotating with constant angular velocity about the z-axis in a fluid occupying a semi-infinite region which, at large distances from the disc, has velocity field proportional to (x,-y,O) with respect to a Cartesian coordinate system. It is shown that when the rate of rotation is large, Karman's exact solution for a disc rotating in an otherwise motionless fluid is recovered. In the limit of zero rotation rate a particular form of Howarth's exact solution for three-dimensional stagnation point flow is obtained. The unsteady form of the partial differential system describing this class of flow may be generalized to time-periodic equilibrium flows. In addition the unsteady equations are shown to describe a strongly nonlinear instability of Karman's rotating disc flow. It is shown that sufficiently large perturbations lead to a finite time breakdown of that flow whilst smaller disturbances decay to zero. If the stagnation point flow at infinity is sufficiently strong, the steady basic states become linearly unstable. In fact there is then a continuous spectrum of unstable eigenvalues of the stability equations but, if the initial value problem is considered, it is found that, at large values of time, the continuous spectrum leads to a velocity field growing exponentially in time with an amplitude decaying algebraically in time.

  16. Novel Driving Method for Two-Dimensional and Three-Dimensional Switchable Active Matrix Organic Light-Emitting Diode Displays for Emission and Programming Time Extension

    NASA Astrophysics Data System (ADS)

    In, Hai-Jung; Kwon, Oh-Kyong

    2012-03-01

    A novel driving method for two-dimensional (2D) and three-dimensional (3D) switchable active matrix organic light-emitting diode (AMOLED) displays is proposed to extend emission time and data programming time during 3D display operation. The proposed pixel consists of six thin-film transistors (TFTs) and two capacitors, and the aperture ratio of the pixel is 45.8% under 40-in. full-high-definition television condition. By increasing emission time and programming time, the flicker problem can be reduced and the lifetime of AMOLED displays can be extended owing to the decrease in emission current density. Simulation results show that the emission current error range from -0.4 to 1.6% is achieved when the threshold voltage variation of driving TFTs is in the range from -1.0 to 1.0 V, and the emission current error is 1.0% when the power line IR-drop is 2.0 V.

  17. Real time automated inspection

    DOEpatents

    Fant, K.M.; Fundakowski, R.A.; Levitt, T.S.; Overland, J.E.; Suresh, B.R.; Ulrich, F.W.

    1985-05-21

    A method and apparatus are described relating to the real time automatic detection and classification of characteristic type surface imperfections occurring on the surfaces of material of interest such as moving hot metal slabs produced by a continuous steel caster. A data camera transversely scans continuous lines of such a surface to sense light intensities of scanned pixels and generates corresponding voltage values. The voltage values are converted to corresponding digital values to form a digital image of the surface which is subsequently processed to form an edge-enhanced image having scan lines characterized by intervals corresponding to the edges of the image. The edge-enhanced image is thresholded to segment out the edges and objects formed by the edges by interval matching and bin tracking. Features of the objects are derived and such features are utilized to classify the objects into characteristic type surface imperfections. 43 figs.

  18. Real time automated inspection

    DOEpatents

    Fant, Karl M.; Fundakowski, Richard A.; Levitt, Tod S.; Overland, John E.; Suresh, Bindinganavle R.; Ulrich, Franz W.

    1985-01-01

    A method and apparatus relating to the real time automatic detection and classification of characteristic type surface imperfections occurring on the surfaces of material of interest such as moving hot metal slabs produced by a continuous steel caster. A data camera transversely scans continuous lines of such a surface to sense light intensities of scanned pixels and generates corresponding voltage values. The voltage values are converted to corresponding digital values to form a digital image of the surface which is subsequently processed to form an edge-enhanced image having scan lines characterized by intervals corresponding to the edges of the image. The edge-enhanced image is thresholded to segment out the edges and objects formed by the edges are segmented out by interval matching and bin tracking. Features of the objects are derived and such features are utilized to classify the objects into characteristic type surface imperfections.

  19. Using the Bi-Orthogonal Decomposition framework to compute the three dimensional Empirical Orthogonal Functions of stratospheric planetary waves from time correlation matrices

    NASA Astrophysics Data System (ADS)

    Rolland, Joran; Domeisen, Daniela I. V.

    2016-04-01

    Many geophysical waves in the atmosphere or in the ocean have a three dimensional structure and contain a range of scales. This is for instance the case of planetary waves in the stratosphere connected to baroclinic eddies in the troposphere [1]. In the study of such waves from reanalysis data or output of numerical simulations, Empirical Orthogonal Functions (EOF) obtained as a Proper Orthogonal Decomposition of the data sets have been of great help. However, most of these computations rely on the diagonalisation of space correlation matrices: this means that the considered data set can only have a limited number of gridpoints. The main consequence is that such analyses are often only performed in planes (as function of height and latitude, or longitude and latitude for instance), which makes the educing of the three dimensional structure of the wave quite difficult. In the case of the afore mentionned waves, the matter of the longitudinal dependence or the proper correlation between modes through the tropopause is an open question. An elegant manner to circumvent this problem is to consider the output of the Orthogonal Decomposition as a whole. Indeed, it has been shown that the normalised time series of the amplitude of each EOF, far from just being decorrelated from one another, are actually another set of orthogonal functions. These can actually be computed through the diagonlisation of the time correlation matrix of the data set, just like the EOF were the result of the diagonalisation of the space correlation matrix. The signal is then fully decomposed in the framework of the Bi-Orthogonal Decomposition as the sum of the nth explained variance, time the nth eigenmode of the time correlation times the nth eigenmode of the spacial correlations [2,3]. A practical consequence of this result is that the EOF can be reconstructed from the projection of the dataset onto the eigenmodes of the time correlation matrix in the so-called snapshot method [4]. This is very

  20. Using the Bi-Orthogonal Decomposition framework to compute the three dimensional Empirical Orthogonal Functions of stratospheric planetary waves from time correlation matrices

    NASA Astrophysics Data System (ADS)

    Rolland, Joran; Domeisen, Daniela I. V.

    2016-04-01

    Many geophysical waves in the atmosphere or in the ocean have a three dimensional structure and contain a range of scales. This is for instance the case of planetary waves in the stratosphere connected to baroclinic eddies in the troposphere [1]. In the study of such waves from reanalysis data or output of numerical simulations, Empirical Orthogonal Functions (EOF) obtained as a Proper Orthogonal Decomposition of the data sets have been of great help. However, most of these computations rely on the diagonalisation of space correlation matrices: this means that the considered data set can only have a limited number of gridpoints. The main consequence is that such analyses are often only performed in planes (as function of height and latitude, or longitude and latitude for instance), which makes the educing of the three dimensional structure of the wave quite difficult. In the case of the afore mentionned waves, the matter of the longitudinal dependence or the proper correlation between modes through the tropopause is an open question. An elegant manner to circumvent this problem is to consider the output of the Orthogonal Decomposition as a whole. Indeed, it has been shown that the normalised time series of the amplitude of each EOF, far from just being decorrelated from one another, are actually another set of orthogonal functions. These can actually be computed through the diagonlisation of the time correlation matrix of the data set, just like the EOF were the result of the diagonalisation of the space correlation matrix. The signal is then fully decomposed in the framework of the Bi-Orthogonal Decomposition as the sum of the nth explained variance, time the nth eigenmode of the time correlation times the nth eigenmode of the spacial correlations [2,3]. A practical consequence of this result is that the EOF can be reconstructed from the projection of the dataset onto the eigenmodes of the time correlation matrix in the so-called snapshot method [4]. This is very

  1. Characterization of a detector chain using a FPGA-based time-to-digital converter to reconstruct the three-dimensional coordinates of single particles at high flux.

    PubMed

    Nogrette, F; Heurteau, D; Chang, R; Bouton, Q; Westbrook, C I; Sellem, R; Clément, D

    2015-11-01

    We report on the development of a novel FPGA-based time-to-digital converter and its implementation in a detection chain that records the coordinates of single particles along three dimensions. The detector is composed of micro-channel plates mounted on top of a cross delay line and connected to fast electronics. We demonstrate continuous recording of the timing signals from the cross delay line at rates up to 4.1 × 10(6) s(-1) and three-dimensional reconstruction of the coordinates up to 3.2 × 10(6) particles per second. From the imaging of a calibrated structure we measure the in-plane resolution of the detector to be 140(20) μm at a flux of 3 × 10(5) particles per second. In addition, we analyze a method to estimate the resolution without placing any structure under vacuum, a significant practical improvement. While we use UV photons here, the results of this work apply to the detection of other kinds of particles.

  2. Characterization of a detector chain using a FPGA-based time-to-digital converter to reconstruct the three-dimensional coordinates of single particles at high flux

    SciTech Connect

    Nogrette, F.; Chang, R.; Bouton, Q.; Westbrook, C. I.; Clément, D.; Heurteau, D.; Sellem, R.

    2015-11-15

    We report on the development of a novel FPGA-based time-to-digital converter and its implementation in a detection chain that records the coordinates of single particles along three dimensions. The detector is composed of micro-channel plates mounted on top of a cross delay line and connected to fast electronics. We demonstrate continuous recording of the timing signals from the cross delay line at rates up to 4.1 × 10{sup 6} s{sup −1} and three-dimensional reconstruction of the coordinates up to 3.2 × 10{sup 6} particles per second. From the imaging of a calibrated structure we measure the in-plane resolution of the detector to be 140(20) μm at a flux of 3 × 10{sup 5} particles per second. In addition, we analyze a method to estimate the resolution without placing any structure under vacuum, a significant practical improvement. While we use UV photons here, the results of this work apply to the detection of other kinds of particles.

  3. In-vivo third-harmonic generation microscopy at 1550nm three-dimensional long-term time-lapse studies in living C. elegans embryos

    NASA Astrophysics Data System (ADS)

    Aviles-Espinosa, Rodrigo; Santos, Susana I. C. O.; Brodschelm, Andreas; Kaenders, Wilhelm G.; Alonso-Ortega, Cesar; Artigas, David; Loza-Alvarez, Pablo

    2011-03-01

    In-vivo microscopic long term time-lapse studies require controlled imaging conditions to preserve sample viability. Therefore it is crucial to meet specific exposure conditions as these may limit the applicability of established techniques. In this work we demonstrate the use of third harmonic generation (THG) microscopy for long term time-lapse three-dimensional studies (4D) in living Caenorhabditis elegans embryos employing a 1550 nm femtosecond fiber laser. We take advantage of the fact that THG only requires the existence of interfaces to generate signal or a change in the refractive index or in the χ3 nonlinear coefficient, therefore no markers are required. In addition, by using this wavelength the emitted THG signal is generated at visible wavelengths (516 nm) enabling the use of standard collection optics and detectors operating near their maximum efficiency. This enables the reduction of the incident light intensity at the sample plane allowing to image the sample for several hours. THG signal is obtained through all embryo development stages, providing different tissue/structure information. By means of control samples, we demonstrate that the expected water absorption at this wavelength does not severely compromise sample viability. Certainly, this technique reduces the complexity of sample preparation (i.e. genetic modification) required by established linear and nonlinear fluorescence based techniques. We demonstrate the non-invasiveness, reduced specimen interference, and strong potential of this particular wavelength to be used to perform long-term 4D recordings.

  4. Characterization of a detector chain using a FPGA-based time-to-digital converter to reconstruct the three-dimensional coordinates of single particles at high flux.

    PubMed

    Nogrette, F; Heurteau, D; Chang, R; Bouton, Q; Westbrook, C I; Sellem, R; Clément, D

    2015-11-01

    We report on the development of a novel FPGA-based time-to-digital converter and its implementation in a detection chain that records the coordinates of single particles along three dimensions. The detector is composed of micro-channel plates mounted on top of a cross delay line and connected to fast electronics. We demonstrate continuous recording of the timing signals from the cross delay line at rates up to 4.1 × 10(6) s(-1) and three-dimensional reconstruction of the coordinates up to 3.2 × 10(6) particles per second. From the imaging of a calibrated structure we measure the in-plane resolution of the detector to be 140(20) μm at a flux of 3 × 10(5) particles per second. In addition, we analyze a method to estimate the resolution without placing any structure under vacuum, a significant practical improvement. While we use UV photons here, the results of this work apply to the detection of other kinds of particles. PMID:26628119

  5. Comparison of wave propagation studies in plasmas using three-dimensional finite-difference time-domain and ray-tracing methods

    SciTech Connect

    Chaudhury, Bhaskar; Chaturvedi, Shashank

    2006-12-15

    Power-flow trajectories of electromagnetic waves through a spatially nonuniform plasma have been computed using direct solutions of Maxwell's equations using the three-dimensional finite-difference time-domain (FDTD) method. This method yields accurate information on refraction as well as absorption effects. The method can be used to compute power-flow trajectories for plasmas with arbitrarily varying density profiles, including effects due to arbitrarily shaped conducting or dielectric surfaces bounding the plasma. Furthermore, since FDTD is computationally expensive, especially for parametric studies, it is desirable to use ray tracing to estimate refraction effects. A quantitative comparison is performed between two different methods of obtaining exact and approximate solutions of Maxwell's equations in order to assess their relative utility in different situations. In the present work, we limit ourselves to a cold, collisional, unmagnetized plasma, where the response to electromagnetic waves is fully specified by a dispersion relation based on magnetoionic theory. It is shown that ray tracing in such plasmas yields accurate results only when two conditions are satisfied. Firstly, the density scale length should be long as compared to the free-space wavelength of the incident wave. Secondly, the conduction current should be small as compared to the displacement current in the medium. The second condition is one which has been identified for the first time.

  6. Three-dimensional display technologies

    PubMed Central

    Geng, Jason

    2014-01-01

    The physical world around us is three-dimensional (3D), yet traditional display devices can show only two-dimensional (2D) flat images that lack depth (i.e., the third dimension) information. This fundamental restriction greatly limits our ability to perceive and to understand the complexity of real-world objects. Nearly 50% of the capability of the human brain is devoted to processing visual information [Human Anatomy & Physiology (Pearson, 2012)]. Flat images and 2D displays do not harness the brain’s power effectively. With rapid advances in the electronics, optics, laser, and photonics fields, true 3D display technologies are making their way into the marketplace. 3D movies, 3D TV, 3D mobile devices, and 3D games have increasingly demanded true 3D display with no eyeglasses (autostereoscopic). Therefore, it would be very beneficial to readers of this journal to have a systematic review of state-of-the-art 3D display technologies. PMID:25530827

  7. Off-equilibrium scaling behaviors driven by time-dependent external fields in three-dimensional O(N) vector models.

    PubMed

    Pelissetto, Andrea; Vicari, Ettore

    2016-03-01

    We consider the dynamical off-equilibrium behavior of the three-dimensional O(N) vector model in the presence of a slowly varying time-dependent spatially uniform magnetic field H(t)=h(t)e, where e is an N-dimensional constant unit vector, h(t)=t/t(s), and t(s) is a time scale, at fixed temperature T≤T(c), where T(c) corresponds to the continuous order-disorder transition. The dynamic evolutions start from equilibrium configurations at h(i)<0, correspondingly t(i)<0, and end at time t(f)>0 with h(t(f))>0, or vice versa. We show that the magnetization displays an off-equilibrium scaling behavior close to the transition line H(t)=0. It arises from the interplay among the time t, the time scale t(s), and the finite size L. The scaling behavior can be parametrized in terms of the scaling variables t(s)(κ)/L and t/t(s)(κ(t)), where κ>0 and κ(t)>0 are appropriate universal exponents, which differ at the critical point and for Ttime dependence of the external field. We define a scaling function for the hysteresis loop area of the magnetization that can be used to quantify how far the system is from equilibrium. PMID:27078326

  8. Off-equilibrium scaling behaviors driven by time-dependent external fields in three-dimensional O(N) vector models.

    PubMed

    Pelissetto, Andrea; Vicari, Ettore

    2016-03-01

    We consider the dynamical off-equilibrium behavior of the three-dimensional O(N) vector model in the presence of a slowly varying time-dependent spatially uniform magnetic field H(t)=h(t)e, where e is an N-dimensional constant unit vector, h(t)=t/t(s), and t(s) is a time scale, at fixed temperature T≤T(c), where T(c) corresponds to the continuous order-disorder transition. The dynamic evolutions start from equilibrium configurations at h(i)<0, correspondingly t(i)<0, and end at time t(f)>0 with h(t(f))>0, or vice versa. We show that the magnetization displays an off-equilibrium scaling behavior close to the transition line H(t)=0. It arises from the interplay among the time t, the time scale t(s), and the finite size L. The scaling behavior can be parametrized in terms of the scaling variables t(s)(κ)/L and t/t(s)(κ(t)), where κ>0 and κ(t)>0 are appropriate universal exponents, which differ at the critical point and for Ttime dependence of the external field. We define a scaling function for the hysteresis loop area of the magnetization that can be used to quantify how far the system is from equilibrium.

  9. Joint Inversion of Body-Wave Arrival Times and Surface-Wave Dispersion for Three-Dimensional Seismic Structure Around SAFOD

    NASA Astrophysics Data System (ADS)

    Zhang, Haijiang; Maceira, Monica; Roux, Philippe; Thurber, Clifford

    2014-11-01

    We incorporate body-wave arrival time and surface-wave dispersion data into a joint inversion for three-dimensional P-wave and S-wave velocity structure of the crust surrounding the site of the San Andreas Fault Observatory at Depth. The contributions of the two data types to the inversion are controlled by the relative weighting of the respective equations. We find that the trade-off between fitting the two data types, controlled by the weighting, defines a clear optimal solution. Varying the weighting away from the optimal point leads to sharp increases in misfit for one data type with only modest reduction in misfit for the other data type. All the acceptable solutions yield structures with similar primary features, but the smaller-scale features change substantially. When there is a lower relative weight on the surface-wave data, it appears that the solution over-fits the body-wave data, leading to a relatively rough V s model, whereas for the optimal weighting, we obtain a relatively smooth model that is able to fit both the body-wave and surface-wave observations adequately.

  10. Monitoring the response to neoadjuvant hormone therapy for locally advanced breast cancer using three-dimensional time-resolved optical mammography

    NASA Astrophysics Data System (ADS)

    Enfield, Louise; Cantanhede, Gabriel; Douek, Michael; Ramalingam, Vernie; Purushotham, Arnie; Hebden, Jem; Gibson, Adam

    2013-05-01

    Optical mammography is a functional imaging technique that uses near-infrared light to produce three-dimensional breast images of tissue oxygen saturation and hemoglobin concentration. It has been used to monitor the response to neoadjuvant chemotherapy in breast cancer patients. We present the first results on monitoring tumor response to hormone therapy using optical mammography. We present three case studies from postmenopausal women treated with neoadjuvant hormone therapy for locally advanced breast cancer. The women were scanned before starting treatment, once during treatment, and then before surgery. Changes in physiological and optical properties within the tumor and in the rest of the breast were evaluated. At the time of surgery, two patients partially responded to treatment and one did not respond. The patients that partially responded on ultrasound revealed a corresponding recovery to normal in the hemoglobin concentration images, whereas the nonresponder indicated an increase in hemoglobin concentration in the tumor compared to her pretreatment images. These case studies suggest that optical imaging of the breast during neoadjuvant hormone treatment can provide potentially valuable information, and that physiological changes within the tumor can be seen in response to treatment.

  11. Three-Dimensional Time-of-Flight Magnetic Resonance Angiography Detection of Duplication of the Vertebral Artery in a Large Chinese Population

    PubMed Central

    Li, Shuhua; Li, Yunyun; Bai, Min; Zhang, Chuanchen

    2016-01-01

    Background The aim of this study was to investigate duplication of the vertebral artery (VA) using three-dimensional time-of-flight (3D TOF) magnetic resonance angiography (MRA) in a large study population to further our understanding of vascular variations. Material/Methods A retrospective analysis of 3D TOF-MRA data in 12 826 cases was performed. The occurrence rate of VA duplication was calculated and accompanied vascular anomalies were recoded. Results Twenty-one VA duplication patients were found, with an occurrence rate of 0.164%; 12 of them had left VA duplication with 2 branches initially arising from the aortic arch and left subclavian artery; 9 of them were right VA duplication with the branches originating from the right subclavian artery. In the 21 cases, 11 had other vascular abnormalities. Conclusions VA duplication is very rare and often associated with other vascular abnormalities. 3D TOF-MRA can accurately display the duplication variation. Better understanding of the variation is instrumental for disease diagnosis, interventional therapy, and surgical operation. PMID:27749814

  12. Time-lapse ultrashort pulse microscopy of infection in three-dimensional versus two-dimensional culture environments reveals enhanced extra-chromosomal virus replication compartment formation

    NASA Astrophysics Data System (ADS)

    Gibbs, Holly C.; Sing, Garwin; Armas, Juan Carlos González; Campbell, Colin J.; Ghazal, Peter; Yeh, Alvin T.

    2013-03-01

    The mechanisms that enable viruses to harness cellular machinery for their own survival are primarily studied in cell lines cultured in two-dimensional (2-D) environments. However, there are increasing reports of biological differences between cells cultured in 2-D versus three-dimensional (3-D) environments. Here we report differences in host-virus interactions based on differences in culture environment. Using ultrashort pulse microscopy (UPM), a form of two-photon microscopy that utilizes sub-10-fs pulses to efficiently excite fluorophores, we have shown that de novo development of extra-chromosomal virus replication compartments (VRCs) upon murine cytomegalovirus (mCMV) infection is markedly enhanced when host cells are cultured in 3-D collagen gels versus 2-D monolayers. In addition, time-lapse imaging revealed that mCMV-induced VRCs have the capacity to grow by coalescence. This work supports the future potential of 3-D culture as a useful bridge between traditional monolayer cultures and animal models to study host-virus interactions in a more physiologically relevant environment for the development of effective anti-viral therapeutics. These advances will require broader adoption of modalities, such as UPM, to image deep within scattering tissues.

  13. Real time markerless motion tracking using linked kinematic chains

    DOEpatents

    Luck, Jason P.; Small, Daniel E.

    2007-08-14

    A markerless method is described for tracking the motion of subjects in a three dimensional environment using a model based on linked kinematic chains. The invention is suitable for tracking robotic, animal or human subjects in real-time using a single computer with inexpensive video equipment, and does not require the use of markers or specialized clothing. A simple model of rigid linked segments is constructed of the subject and tracked using three dimensional volumetric data collected by a multiple camera video imaging system. A physics based method is then used to compute forces to align the model with subsequent volumetric data sets in real-time. The method is able to handle occlusion of segments and accommodates joint limits, velocity constraints, and collision constraints and provides for error recovery. The method further provides for elimination of singularities in Jacobian based calculations, which has been problematic in alternative methods.

  14. ChromAlign: A two-step algorithmic procedure for time alignment of three-dimensional LC-MS chromatographic surfaces.

    PubMed

    Sadygov, Rovshan G; Maroto, Fernando Martin; Hühmer, Andreas F R

    2006-12-15

    We present an algorithmic approach to align three-dimensional chromatographic surfaces of LC-MS data of complex mixture samples. The approach consists of two steps. In the first step, we prealign chromatographic profiles: two-dimensional projections of chromatographic surfaces. This is accomplished by correlation analysis using fast Fourier transforms. In this step, a temporal offset that maximizes the overlap and dot product between two chromatographic profiles is determined. In the second step, the algorithm generates correlation matrix elements between full mass scans of the reference and sample chromatographic surfaces. The temporal offset from the first step indicates a range of the mass scans that are possibly correlated, then the correlation matrix is calculated only for these mass scans. The correlation matrix carries information on highly correlated scans, but it does not itself determine the scan or time alignment. Alignment is determined as a path in the correlation matrix that maximizes the sum of the correlation matrix elements. The computational complexity of the optimal path generation problem is reduced by the use of dynamic programming. The program produces time-aligned surfaces. The use of the temporal offset from the first step in the second step reduces the computation time for generating the correlation matrix and speeds up the process. The algorithm has been implemented in a program, ChromAlign, developed in C++ language for the .NET2 environment in WINDOWS XP. In this work, we demonstrate the applications of ChromAlign to alignment of LC-MS surfaces of several datasets: a mixture of known proteins, samples from digests of surface proteins of T-cells, and samples prepared from digests of cerebrospinal fluid. ChromAlign accurately aligns the LC-MS surfaces we studied. In these examples, we discuss various aspects of the alignment by ChromAlign, such as constant time axis shifts and warping of chromatographic surfaces.

  15. Real time polarimetric dehazing.

    PubMed

    Mudge, Jason; Virgen, Miguel

    2013-03-20

    Remote sensing is a rich topic due to its utility in gathering detailed accurate information from locations that are not economically feasible traveling destinations or are physically inaccessible. However, poor visibility over long path lengths is problematic for a variety of reasons. Haze induced by light scatter is one cause for poor visibility and is the focus of this article. Image haze comes about as a result of light scattering off particles and into the imaging path causing a haziness to appear on the image. Image processing using polarimetric information of light scatter can be used to mitigate image haze. An imaging polarimeter which provides the Stokes values in real time combined with a "dehazing" algorithm can automate image haze removal for instant applications. Example uses are to improve visual display providing on-the-spot detection or imbedding in an active control loop to improve viewing and tracking while on a moving platform. In addition, removing haze in this manner allows the trade space for a system operational waveband to be opened up to bands which are object matched and not necessarily restricted by scatter effects. PMID:23518739

  16. Three-dimensional seismic tomography from P wave and S wave microearthquake travel times and rock physics characterization of the Campi Flegrei Caldera

    NASA Astrophysics Data System (ADS)

    Vanorio, T.; Virieux, J.; Capuano, P.; Russo, G.

    2005-03-01

    The Campi Flegrei (CF) Caldera experiences dramatic ground deformations unsurpassed anywhere in the world. The source responsible for this phenomenon is still debated. With the aim of exploring the structure of the caldera as well as the role of hydrothermal fluids on velocity changes, a multidisciplinary approach dealing with three-dimensional delay time tomography and rock physics characterization has been followed. Selected seismic data were modeled by using a tomographic method based on an accurate finite difference travel time computation which simultaneously inverts P wave and S wave first-arrival times for both velocity model parameters and hypocenter locations. The retrieved P wave and S wave velocity images as well as the deduced Vp/Vs images were interpreted by using experimental measurements of rock physical properties on CF samples to take into account steam/water phase transition mechanisms affecting P wave and S wave velocities. Also, modeling of petrophysical properties for site-relevant rocks constrains the role of overpressured fluids on velocity. A flat and low Vp/Vs anomaly lies at 4 km depth under the city of Pozzuoli. Earthquakes are located at the top of this anomaly. This anomaly implies the presence of fractured overpressured gas-bearing formations and excludes the presence of melted rocks. At shallow depth, a high Vp/Vs anomaly located at 1 km suggests the presence of rocks containing fluids in the liquid phase. Finally, maps of the Vp*Vs product show a high Vp*Vs horseshoe-shaped anomaly located at 2 km depth. It is consistent with gravity data and well data and might constitute the on-land remainder of the caldera rim, detected below sea level by tomography using active source seismic data.

  17. A comparison of inner ear imaging features at different time points of sudden sensorineural hearing loss with three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging.

    PubMed

    Zhu, Honglei; Ou, Yongkang; Fu, Jia; Zhang, Ya; Xiong, Hao; Xu, Yaodong

    2015-10-01

    It has been reported that about half of patients with sudden sensorineural hearing loss (SSNHL) show high signals in the affected inner ear on three-dimensional, fluid-attenuated inversion recovery magnetic resonance imaging (3D-FLAIR MRI). These signals may reflect minor hemorrhage or an increased concentration of protein in the inner ear, which has passed through blood vessels with increased permeability. Our objective was to compare the positive ratio of the high signal in affected inner ears at different time points to determine the suitable imaging time point for 3D-FLAIR MRI in SSNHL. 3D-FLAIR MRI images were taken at three times, precontrast and approximately 10 min and 4 h after intravenous injection of a single dose of gadodiamide (Gd) (0.1 mmol/kg), in 46 patients with SNHL. We compared the positive findings of the high signals in the inner ear of patients with SNHL as well as the signal intensity ratio (SIR) between the affected cochleae and unaffected cochleae at three time points. The positive ratios of the high signals in the affected inner ear at the time points of precontrast and 10 min and 4 h after the intravenous Gd injection were 26.1, 32.6, and 41.3%, respectively. The high signal intensity ratios of affected inner ears at the three time points were 1.28, 1.31, and 1.48, respectively. The difference between the positive ratios precontrast and at 10 min after the intravenous Gd injection was statistically significant (P = 0.006); the differences between the positive ratios at 4 h after the intravenous Gd injection and precontrast and between the ratios at 4 h and 10 min after the intravenous Gd injection were not statistically significant. The time effects of the median value of SIR were not significant (P = 0.064). We do not recommend 4 h after intravenous Gd injection as a time point to image the inner ear in SNHL. We believe that imaging precontrast and at 10 min after the intravenous Gd injection are suitable time points.

  18. Performance of asynchronous fiber-optic code division multiple access system based on three-dimensional wavelength/time/space codes and its link analysis.

    PubMed

    Singh, Jaswinder

    2010-03-10

    A novel family of three-dimensional (3-D) wavelength/time/space codes for asynchronous optical code-division-multiple-access (CDMA) systems with "zero" off-peak autocorrelation and "unity" cross correlation is reported. Antipodal signaling and differential detection is employed in the system. A maximum of [(W x T+1) x W] codes are generated for unity cross correlation, where W and T are the number of wavelengths and time chips used in the code and are prime. The conditions for violation of the cross-correlation constraint are discussed. The expressions for number of generated codes are determined for various code dimensions. It is found that the maximum number of codes are generated for S < or = min(W,T), where W and T are prime and S is the number of space channels. The performance of these codes is compared to the earlier reported two-dimensional (2-D)/3-D codes for asynchronous systems. The codes have a code-set-size to code-size ratio greater than W/S. For instance, with a code size of 2065 (59 x 7 x 5), a total of 12,213 users can be supported, and 130 simultaneous users at a bit-error rate (BER) of 10(-9). An arrayed-waveguide-grating-based reconfigurable encoder/decoder design for 2-D implementation for the 3-D codes is presented so that the need for multiple star couplers and fiber ribbons is eliminated. The hardware requirements of the coders used for various modulation/detection schemes are given. The effect of insertion loss in the coders is shown to be significantly reduced with loss compensation by using an amplifier after encoding. An optical CDMA system for four users is simulated and the results presented show the improvement in performance with the use of loss compensation.

  19. Beating the wavelength limit: three-dimensional imaging of buried subwavelength fractures in sculpture and construction materials by terahertz time-domain reflection spectroscopy.

    PubMed

    Schwerdtfeger, M; Castro-Camus, E; Krügener, K; Viöl, W; Koch, M

    2013-01-20

    We use reflection terahertz spectroscopy to locate and produce three-dimensional images of air gaps between stones that resemble fractures, even of subwavelength thicknesses. This technique is found to be promising tool for sculpture and building damage evaluation as well as structural quality control in other dielectric materials. PMID:23338182

  20. Occlusion-free monocular three-dimensional vision system

    NASA Astrophysics Data System (ADS)

    Theodoracatos, Vassilios E.

    1994-10-01

    This paper describes a new, occlusion-free, monocular three-dimensional vision system. A matrix of light beams (lasers, fiber optics, etc.), substantially parallel to the optic axis of the lens of a video camera, is projected onto a scene. The corresponding coordinates of the perspective image generated on the video-camera sensor, the focal length of the camera lens, and the lateral position of the projected beams of light are used to determine the 'perspective depth' z* of the three-dimensional real image in the space between the lens and the image plane. Direct inverse perspective transformations are used to reconstruct the three- dimensional real-world scene. This system can lead to the development of three-dimensional real-image sensing devices for manufacturing, medical, and defense-related applications. If combined with existing technology, it has high potential for the development of three- dimensional television.

  1. Three-dimensional time-of-flight MR angiography for evaluation of intracranial aneurysms after endosaccular packing with Guglielmi detachable coils: comparison with 3D digital subtraction angiography.

    PubMed

    Okahara, Mika; Kiyosue, Hiro; Hori, Yuzo; Yamashita, Masanori; Nagatomi, Hirofumi; Mori, Hiromu

    2004-07-01

    The sensitivities and specificities of three-dimensional time-of-flight MR angiography (3D-TOF MRA) and 3D digital subtraction angiography (3D-DSA) were compared for evaluation of cerebral aneurysms after endosaccular packing with Guglielmi detachable coils (GDCs). Thirty-three patients with 33 aneurysms were included in this prospective study. 3D-TOF MRA and 3D-DSA were performed in the same week on all patients. Maximal intensity projection (MIP) and 3D reconstructed MRA images were compared with 3D-DSA images. The diameters of residual/recurrent aneurysms detected on 3D-DSA were calculated on a workstation. In 3 (9%) of 33 aneurysms, 3D-TOF MRA did not provide reliable information due to significant susceptibility artifacts on MRA. The sensitivity and specificity rates of MRA were 72.7 and 90.9%, respectively, for the diagnosis of residual/recurrent aneurysm. The diameters of residual/recurrent aneurysms that could not be detected by MRA were significantly smaller than those of detected aneurysms (mean 1.1 vs mean 2.3 mm). In one aneurysm of the anterior communicating artery (ACoA), the relationship between the residual aneurysm and the ACoA was more evident on MRA than DSA images. MRA can detect the recurrent/residual lumen of aneurysms treated with GDCs of up to at least 1.8 mm in diameter. 3D-TOF MRA is useful for follow-up of intracranial aneurysms treated with GDCs, and could partly replace DSA.

  2. Three-Dimensional Schlieren Measurements

    NASA Astrophysics Data System (ADS)

    Sutherland, Bruce; Cochrane, Andrea

    2004-11-01

    Schlieren systems visualise disturbances that change the index of refraction of a fluid, for example due to temperature or salinity disturbances. `Synthetic schlieren' refers to a recent advance in which these disturbances are visualised with a digital camera and image-processing technology rather than the classical use of parabolic mirrors and a knife-edge. In a typical setup, light from an image of horizontal lines or dots passes almost horizontally through the test section of a fluid to a CCD camera. Refractive index disturbances distort the image and digital comparison of successive images reveals the plan-form structure and time evolution of the disturbances. If the disturbance is effectively two-dimensional, meaning that it is uniform across the line-of-sight of the camera, then its magnitude as well as its structure can measured through simple inversion of an algebraic equation. If the structure is axisymmetric with rotation-axis perpendicular to the line of sight, the magnitude of the disturbance can be measured through inversion of a non-singular square matrix. Here we report upon the extension of this work toward measuring the magnitude of a fully three-dimensional disturbance. This is done by analysing images from two perspectives through the test section and using inversion tomography techniques to reconstruct the disturbance field. The results are tested against theoretical predictions and experimental measurements.

  3. Real-Time Benchmark Suite

    1992-01-17

    This software provides a portable benchmark suite for real time kernels. It tests the performance of many of the system calls, as well as the interrupt response time and task response time to interrupts. These numbers provide a baseline for comparing various real-time kernels and hardware platforms.

  4. Application of a real-space three-dimensional image reconstruction method in the structural analysis of noncrystalline biological macromolecules enveloped by water in coherent x-ray diffraction microscopy.

    PubMed

    Kodama, Wataru; Nakasako, Masayoshi

    2011-08-01

    Coherent x-ray diffraction microscopy is a novel technique in the structural analyses of particles that are difficult to crystallize, such as the biological particles composing living cells. As water is indispensable for maintaining particles in functional structures, sufficient hydration of targeted particles is required during sample preparation for diffraction microscopy experiments. However, the water enveloping particles also contributes significantly to the diffraction patterns and reduces the electron-density contrast of the sample particles. In this study, we propose a protocol for the structural analyses of particles in water by applying a three-dimensional reconstruction method in real space for the projection images phase-retrieved from diffraction patterns, together with a developed density modification technique. We examined the feasibility of the protocol through three simulations involving a protein molecule in a vacuum, and enveloped in either a droplet or a cube-shaped water. The simulations were carried out for the diffraction patterns in the reciprocal planes normal to the incident x-ray beam. This assumption and the simulation conditions corresponded to experiments using x-ray wavelengths of shorter than 0.03 Å. The analyses demonstrated that our protocol provided an interpretable electron-density map. Based on the results, we discuss the advantages and limitations of the proposed protocol and its practical application for experimental data. In particular, we examined the influence of Poisson noise in diffraction patterns on the reconstructed three-dimensional electron density in the proposed protocol.

  5. Three-dimensional RF structure calculations

    NASA Astrophysics Data System (ADS)

    Cooper, R. K.; Browman, M. J.; Weiland, T.

    1989-04-01

    The calculation of three-dimensional rf structures is rapidly approaching adolescence, after having been in its infancy for the last four years. This paper will show the kinds of calculations that are currently being performed in the frequency domain and is a companion paper to one in which time-domain calculations are described.

  6. Three-dimensional rf structure calculations

    SciTech Connect

    Cooper, R.K.; Browman, M.J.; Weiland, T.

    1988-01-01

    The calculation of three-dimensional rf structures is rapidly approaching adolescence, after having been in its infancy for the last four years. This paper will show the kinds of calculations that are currently being performed in the frequency domain and is a companion paper to one in which time-domain calculations are described. 13 refs., 14 figs.

  7. Three-dimensional marginal separation

    NASA Technical Reports Server (NTRS)

    Duck, Peter W.

    1988-01-01

    The three dimensional marginal separation of a boundary layer along a line of symmetry is considered. The key equation governing the displacement function is derived, and found to be a nonlinear integral equation in two space variables. This is solved iteratively using a pseudo-spectral approach, based partly in double Fourier space, and partly in physical space. Qualitatively, the results are similar to previously reported two dimensional results (which are also computed to test the accuracy of the numerical scheme); however quantitatively the three dimensional results are much different.

  8. Three-dimensional silicon micromachining

    NASA Astrophysics Data System (ADS)

    Azimi, S.; Song, J.; Dang, Z. Y.; Liang, H. D.; Breese, M. B. H.

    2012-11-01

    A process for fabricating arbitrary-shaped, two- and three-dimensional silicon and porous silicon components has been developed, based on high-energy ion irradiation, such as 250 keV to 1 MeV protons and helium. Irradiation alters the hole current flow during subsequent electrochemical anodization, allowing the anodization rate to be slowed or stopped for low/high fluences. For moderate fluences the anodization rate is selectively stopped only at depths corresponding to the high defect density at the end of ion range, allowing true three-dimensional silicon machining. The use of this process in fields including optics, photonics, holography and nanoscale depth machining is reviewed.

  9. Time dependent three-dimensional body frame quantal wave packet treatment of the H + H2 exchange reaction on the Liu-Siegbahn-Truhlar-Horowitz (LSTH) surface

    NASA Technical Reports Server (NTRS)

    Neuhauser, Daniel; Baer, Michael; Judson, Richard S.; Kouri, Donald J.

    1989-01-01

    The first successful application of the three-dimensional quantum body frame wave packet approach to reactive scattering is reported for the H + H2 exchange reaction on the LSTH potential surface. The method used is based on a procedure for calculating total reaction probabilities from wave packets. It is found that converged, vibrationally resolved reactive probabilities can be calculated with a grid that is not much larger than required for the pure inelastic calculation. Tabular results are presented for several energies.

  10. Joint Inversion of Body-Wave Arrival Times and Surface-Wave Dispersion Data for Three-Dimensional Seismic Velocity Structure Around SAFOD

    NASA Astrophysics Data System (ADS)

    Zhang, H.; Thurber, C. H.; Maceira, M.; Roux, P.

    2013-12-01

    The crust around the San Andreas Fault Observatory at depth (SAFOD) has been the subject of many geophysical studies aimed at characterizing in detail the fault zone structure and elucidating the lithologies and physical properties of the surrounding rocks. Seismic methods in particular have revealed the complex two-dimensional (2D) and three-dimensional (3D) structure of the crustal volume around SAFOD and the strong velocity reduction in the fault damage zone. In this study we conduct a joint inversion using body-wave arrival times and surface-wave dispersion data to image the P-and S-wave velocity structure of the upper crust surrounding SAFOD. The two data types have complementary strengths - the body-wave data have good resolution at depth, albeit only where there are crossing rays between sources and receivers, whereas the surface waves have very good near-surface resolution and are not dependent on the earthquake source distribution because they are derived from ambient noise. The body-wave data are from local earthquakes and explosions, comprising the dataset analyzed by Zhang et al. (2009). The surface-wave data are for Love waves from ambient noise correlations, and are from Roux et al. (2011). The joint inversion code is based on the regional-scale version of the double-difference (DD) tomography algorithm tomoDD. The surface-wave inversion code that is integrated into the joint inversion algorithm is from Maceira and Ammon (2009). The propagator matrix solver in the algorithm DISPER80 (Saito, 1988) is used for the forward calculation of dispersion curves from layered velocity models. We examined how the structural models vary as we vary the relative weighting of the fit to the two data sets and in comparison to the previous separate inversion results. The joint inversion with the 'optimal' weighting shows more clearly the U-shaped local structure from the Buzzard Canyon Fault on the west side of SAF to the Gold Hill Fault on the east side.

  11. Three-dimensional landing zone ladar

    NASA Astrophysics Data System (ADS)

    Savage, James; Goodrich, Shawn; Burns, H. N.

    2016-05-01

    Three-Dimensional Landing Zone (3D-LZ) refers to a series of Air Force Research Laboratory (AFRL) programs to develop high-resolution, imaging ladar to address helicopter approach and landing in degraded visual environments with emphasis on brownout; cable warning and obstacle avoidance; and controlled flight into terrain. Initial efforts adapted ladar systems built for munition seekers, and success led to a the 3D-LZ Joint Capability Technology Demonstration (JCTD) , a 27-month program to develop and demonstrate a ladar subsystem that could be housed with the AN/AAQ-29 FLIR turret flown on US Air Force Combat Search and Rescue (CSAR) HH-60G Pave Hawk helicopters. Following the JCTD flight demonstration, further development focused on reducing size, weight, and power while continuing to refine the real-time geo-referencing, dust rejection, obstacle and cable avoidance, and Helicopter Terrain Awareness and Warning (HTAWS) capability demonstrated under the JCTD. This paper summarizes significant ladar technology development milestones to date, individual LADAR technologies within 3D-LZ, and results of the flight testing.

  12. Three dimensional characterization and archiving system

    SciTech Connect

    Sebastian, R.L.; Clark, R.; Gallman, P.

    1995-12-01

    The Three Dimensional Characterization and Archiving System (3D-ICAS) is being developed as a remote system to perform rapid in situ analysis of hazardous organics and radionuclide contamination on structural materials. Coleman Research and its subcontractors, Thermedics Detection, Inc. (TD) and the University of Idaho (UI) are in the second phase of a three phase program to develop 3D-ICAS to support Decontamination and Decommissioning (D&D) operations. Accurate physical characterization of surfaces and the radioactive and organic is a critical D&D task. Surface characterization includes identification of potentially dangerous inorganic materials, such as asbestos and transite. Real-time remotely operable characterization instrumentation will significantly advance the analysis capabilities beyond those currently employed. Chemical analysis is a primary area where the characterization process will be improved. Chemical analysis plays a vital role throughout the process of decontamination. Before clean-up operations can begin the site must be characterized with respect to the type and concentration of contaminants, and detailed site mapping must clarify areas of both high and low risk. During remediation activities chemical analysis provides a means to measure progress and to adjust clean-up strategy. Once the clean-up process has been completed the results of chemical analysis will verify that the site is in compliance with federal and local regulations.

  13. Three dimensional characterization and archiving system

    SciTech Connect

    Sebastian, R.L.; Clark, R.; Gallman, P.

    1996-04-01

    The Three Dimensional Characterization and Archiving System (3D-ICAS) is being developed as a remote system to perform rapid in situ analysis of hazardous organics and radionuclide contamination on structural materials. Coleman Research and its subcontractors, Thermedics Detection, Inc. (TD) and the University of Idaho (UI) are in the second phase of a three phase program to develop 3D-ICAS to support Decontamination and Decommissioning (D and D) operations. Accurate physical characterization of surfaces and the radioactive and organic is a critical D and D task. Surface characterization includes identification of potentially dangerous inorganic materials, such as asbestos and transite. Real-time remotely operable characterization instrumentation will significantly advance the analysis capabilities beyond those currently employed. Chemical analysis is a primary area where the characterization process will be improved. The 3D-ICAS system robotically conveys a multisensor probe near the surfaces to be inspected. The sensor position and orientation are monitored and controlled using coherent laser radar (CLR) tracking. The CLR also provides 3D facility maps which establish a 3D world view within which the robotic sensor system can operate.

  14. Three dimensional colorimetric assay assemblies

    SciTech Connect

    Charych, D.; Reichart, A.

    2000-06-27

    A direct assay is described using novel three-dimensional polymeric assemblies which change from a blue to red color when exposed to an analyte, in one case a flu virus. The assemblies are typically in the form of liposomes which can be maintained in a suspension, and show great intensity in their color changes. Their method of production is also described.

  15. The Three-Dimensional Universe.

    ERIC Educational Resources Information Center

    Banks, Dale A.; Powell, Harry D.

    1992-01-01

    Provides instructions for helping students construct a three-dimensional model of a constellation. Aluminum foil spheres with various diameters are used to represent stars with various apparent magnitudes. The positions of the stars in the model are determined from constellation maps and by converting actual star distances into millimeters. (PR)

  16. Three-Dimensional Lissajous Figures.

    ERIC Educational Resources Information Center

    D'Mura, John M.

    1989-01-01

    Described is a mechanically driven device for generating three-dimensional harmonic space figures with different frequencies and phase angles on the X, Y, and Z axes. Discussed are apparatus, viewing stereo pairs, equations of motion, and using space figures in classroom. (YP)

  17. Creating Three-Dimensional Scenes

    ERIC Educational Resources Information Center

    Krumpe, Norm

    2005-01-01

    Persistence of Vision Raytracer (POV-Ray), a free computer program for creating photo-realistic, three-dimensional scenes and a link for Mathematica users interested in generating POV-Ray files from within Mathematica, is discussed. POV-Ray has great potential in secondary mathematics classrooms and helps in strengthening students' visualization…

  18. Three dimensional colorimetric assay assemblies

    DOEpatents

    Charych, Deborah; Reichart, Anke

    2000-01-01

    A direct assay is described using novel three-dimensional polymeric assemblies which change from a blue to red color when exposed to an analyte, in one case a flu virus. The assemblies are typically in the form of liposomes which can be maintained in a suspension, and show great intensity in their color changes. Their method of production is also described.

  19. Three-dimensional stellarator codes

    PubMed Central

    Garabedian, P. R.

    2002-01-01

    Three-dimensional computer codes have been used to develop quasisymmetric stellarators with modular coils that are promising candidates for a magnetic fusion reactor. The mathematics of plasma confinement raises serious questions about the numerical calculations. Convergence studies have been performed to assess the best configurations. Comparisons with recent data from large stellarator experiments serve to validate the theory. PMID:12140367

  20. Three-Dimensional Messages for Interstellar Communication

    NASA Astrophysics Data System (ADS)

    Vakoch, Douglas A.

    One of the challenges facing independently evolved civilizations separated by interstellar distances is to communicate information unique to one civilization. One commonly proposed solution is to begin with two-dimensional pictorial representations of mathematical concepts and physical objects, in the hope that this will provide a foundation for overcoming linguistic barriers. However, significant aspects of such representations are highly conventional, and may not be readily intelligible to a civilization with different conventions. The process of teaching conventions of representation may be facilitated by the use of three-dimensional representations redundantly encoded in multiple formats (e.g., as both vectors and as rasters). After having illustrated specific conventions for representing mathematical objects in a three-dimensional space, this method can be used to describe a physical environment shared by transmitter and receiver: a three-dimensional space defined by the transmitter--receiver axis, and containing stars within that space. This method can be extended to show three-dimensional representations varying over time. Having clarified conventions for representing objects potentially familiar to both sender and receiver, novel objects can subsequently be depicted. This is illustrated through sequences showing interactions between human beings, which provide information about human behavior and personality. Extensions of this method may allow the communication of such culture-specific features as aesthetic judgments and religious beliefs. Limitations of this approach will be noted, with specific reference to ETI who are not primarily visual.

  1. Real-time tracking of objects for space applications using a laser range scanner

    NASA Technical Reports Server (NTRS)

    Blais, F.; Couvillon, R. A.; Rioux, M.; Maclean, S. G.

    1994-01-01

    Real-time tracking of multiple targets and three dimensional object features was demonstrated using a laser range scanner. The prototype was immune to ambient illumination and sun interference. Tracking error feedback was simultaneously obtained from individual targets, global predicted target position, and the human operator. A more complete study of calibration parameters and temperature variations on the scanner is needed to determine the exact performance of the sensor. Lissajous patterns used in three-dimensional real-time tracking prove helpful given their high resolution. The photogrammetry-based Advanced Space Vision System (ASVS) is discussed in combination with the laser range scanner.

  2. Real Time Baseball Database

    NASA Astrophysics Data System (ADS)

    Fukue, Yasuhiro

    The author describes the system outline, features and operations of "Nikkan Sports Realtime Basaball Database" which was developed and operated by Nikkan Sports Shimbun, K. K. The system enables to input numerical data of professional baseball games as they proceed simultaneously, and execute data updating at realtime, just-in-time. Other than serving as supporting tool for prepareing newspapers it is also available for broadcasting media, general users through NTT dial Q2 and others.

  3. Application of VRML for three-dimensional interactive real-time comparison of OCT structures with standard histology

    NASA Astrophysics Data System (ADS)

    Tadrous, Paul J.; Podoleanu, Adrian Gh.; Dobre, George M.; Stamp, Gordon W. H.

    2003-07-01

    Optical coherence tomography (OCT) is a potentially useful 'optical biopsy' tool in medicine. To realize this potential doctors must be able to interpret OCT images with at least the same accuracy as conventional histology. It is therefore important that some accurate method of comparing OCT images with conventional histology be found. Despite numerous OCT vs. conventional histology studies in the literature the methods used for comparison have, by necessity, been approximate because it is not possible to cut a physical tissue section in the same plane as the OCT optical section (partly due to histology processing artefacts). In this paper we present a method of rendering solid tissue volumes with semi-transparency using the Virtual Reality Modelling Language (VRML) and devise a VRML script which allows any two volume data sets to be manipulated within the same region of virtual space. This allows the structure of a whole volume of tissue imaged with OCT to be directly compared with the serial section reconstruction of the conventionally stained histology. As the whole volume is visualized any corresponding tissue regions can be more easily identified despite tissue processing artefacts. We demonstrate the effectiveness of our method usng an ex vivo biopsy of human breast carcinoma.

  4. Guiding Exploration through Three-Dimensional Virtual Environments: A Cognitive Load Reduction Approach

    ERIC Educational Resources Information Center

    Chen, Chwen Jen; Fauzy Wan Ismail, Wan Mohd

    2008-01-01

    The real-time interactive nature of three-dimensional virtual environments (VEs) makes this technology very appropriate for exploratory learning purposes. However, many studies have shown that the exploration process may cause cognitive overload that affects the learning of domain knowledge. This article reports a quasi-experimental study that…

  5. Real-time flutter identification

    NASA Technical Reports Server (NTRS)

    Roy, R.; Walker, R.

    1985-01-01

    The techniques and a FORTRAN 77 MOdal Parameter IDentification (MOPID) computer program developed for identification of the frequencies and damping ratios of multiple flutter modes in real time are documented. Physically meaningful model parameterization was combined with state of the art recursive identification techniques and applied to the problem of real time flutter mode monitoring. The performance of the algorithm in terms of convergence speed and parameter estimation error is demonstrated for several simulated data cases, and the results of actual flight data analysis from two different vehicles are presented. It is indicated that the algorithm is capable of real time monitoring of aircraft flutter characteristics with a high degree of reliability.

  6. Real-time vision systems

    SciTech Connect

    Johnson, R.; Hernandez, J.E.; Lu, Shin-yee

    1994-11-15

    Many industrial and defence applications require an ability to make instantaneous decisions based on sensor input of a time varying process. Such systems are referred to as `real-time systems` because they process and act on data as it occurs in time. When a vision sensor is used in a real-time system, the processing demands can be quite substantial, with typical data rates of 10-20 million samples per second. A real-time Machine Vision Laboratory (MVL) was established in FY94 to extend our years of experience in developing computer vision algorithms to include the development and implementation of real-time vision systems. The laboratory is equipped with a variety of hardware components, including Datacube image acquisition and processing boards, a Sun workstation, and several different types of CCD cameras, including monochrome and color area cameras and analog and digital line-scan cameras. The equipment is reconfigurable for prototyping different applications. This facility has been used to support several programs at LLNL, including O Division`s Peacemaker and Deadeye Projects as well as the CRADA with the U.S. Textile Industry, CAFE (Computer Aided Fabric Inspection). To date, we have successfully demonstrated several real-time applications: bullet tracking, stereo tracking and ranging, and web inspection. This work has been documented in the ongoing development of a real-time software library.

  7. Three-dimensional positional changes of teeth adjacent to posterior edentulous spaces in relation to age at time of tooth loss and elapsed time.

    PubMed

    Petridis, Haralampos P; Tsiggos, Nikolaos; Michail, Achilleas; Kafantaris, Sotirios N; Hatzikyriakos, Andreas; Kafantaris, Nikolaos M

    2010-06-01

    The purpose of this study was to study the stability of teeth adjacent to posterior edentulous spaces and correlate it with patient age and time lapse since tooth loss. Dental casts, panoramic radiographs, and questionnaires of patients treated in a University setting were employed. Teeth adjacent and opposing posterior edentulous spaces were examined for the following parameters: Supraeruption, rotation, space closure, and axial inclination. One hundred twenty three patients with 229 edentulous spaces were analyzed. Statistical analysis showed that the effects of "jaw", "gender", and "age group at the time of tooth loss" were not significant for any of the variables tested. The effect of time lapse since tooth loss was significant regarding the "amount of distal tooth inclination" (P<0.001), the "amount of distal tooth rotation" (P=0.004), and "space closure" (P=0.038). Post-hoc analysis of the "amount of distal tooth inclination" revealed a marked increase in inclination 5 years after tooth loss. Within the limitations of this study, it was concluded that in the group of patients studied, minor positional changes in teeth opposing or adjacent to posterior edentulous spaces had occurred. The greatest changes in position were recorded for mandibular teeth distal to edentulous spaces.

  8. Real-Time Depth Measurement In A Stereoscopic Television Display

    NASA Astrophysics Data System (ADS)

    Robinson, M.; Sood, S. C.

    1983-04-01

    A working prototype three-dimensional television display has been constructed and initial feasibility studies have been carried out. The system employs the time division technique which takes advantage of the interlace facility on the standard television display and incorporates electro-optic viewing spectacles for the observer. Improvements to the basic system have been carried out which include remotely triggered viewing spectacles, thus giving greater freedom of movement to the observer and also an increased switching rate to reduce the effects of flicker. It soon became apparent that a system containing an integral real time depth measurement facility would be attractive to potential users. The method used is the application of a photogrammetic technique to the display in order to provide a real time three dimensional viewing and depth measurement facility. Present available techniques involve processing a stereoscopic pair of photographs which introduces an obvious inherent time delay. For many applications a real time technique has advantages even though the depth resolution is unlikely to be as good as the standard photographic system.

  9. Real-time software receiver

    NASA Technical Reports Server (NTRS)

    Ledvina, Brent M. (Inventor); Psiaki, Mark L. (Inventor); Powell, Steven P. (Inventor); Kintner, Jr., Paul M. (Inventor)

    2007-01-01

    A real-time software receiver that executes on a general purpose processor. The software receiver includes data acquisition and correlator modules that perform, in place of hardware correlation, baseband mixing and PRN code correlation using bit-wise parallelism.

  10. Real-time software receiver

    NASA Technical Reports Server (NTRS)

    Ledvina, Brent M. (Inventor); Psiaki, Mark L. (Inventor); Powell, Steven P. (Inventor); Kintner, Jr., Paul M. (Inventor)

    2006-01-01

    A real-time software receiver that executes on a general purpose processor. The software receiver includes data acquisition and correlator modules that perform, in place of hardware correlation, baseband mixing and PRN code correlation using bit-wise parallelism.

  11. Three-dimensional printing of scintillating materials.

    PubMed

    Mishnayot, Y; Layani, M; Cooperstein, I; Magdassi, S; Ron, G

    2014-08-01

    We demonstrate, for the first time, the applicability of three-dimensional printing techniques to the manufacture of scintillation detectors. We report on the development of a formulation, usable in stereolithographic printing, that exhibits scintillation efficiency on the order of 30% of that of commercial polystyrene based scintillators. We discuss the applicability of these techniques and propose future enhancements that will allow tailoring the printed scintillation detectors to various applications.

  12. Real time visual servoing using controlled illumination

    NASA Astrophysics Data System (ADS)

    Urban, J. P.; Motyl, G.; Gallice, J.

    1994-02-01

    A real-time visual servoing approach is applied to robotics tasks consisting of the positioning of the end effector with respect to a priori known polyhedral objects. The vision apparatus is consituted by a compact CCD camera rigidly coupled with two laser stripes mounted on the wrist of a robot manipulator. The objective is to servo the robot and effector at a constant position and orientation with respect to a known object in three- dimensional space in the field of view of the sensory system. The approach is expressed in terms of sensor-based control applied to visual servoing. In the case of camera-light stripe coupling, the elementary visual signals used for visual servoing are the points of discontinuity in the light stripes. The feasibility of the approach is demonstrated in a factory automation task consisting of the positioning of the end-effector tool over a vehicle battery. Both simulation and experimentation results are presented, proving the robustness and stability of the algorithm.

  13. Real-Time Moire Holography

    NASA Astrophysics Data System (ADS)

    Soares, O. D. D.; Lage, A. I. V. S.

    1986-08-01

    Interferometric techniques including hologrametry, both classical and electronic, present high sensitivity making difficult its practical use in real-time. The introduction of the differencial concept as moire evaluation techniques permits to use with advantage an arbitrary reference pattern within the correlation range. The carrier spatial spectrum can be directly the interferogram fringe pattern instead of the original interference pattern of wavelength dimensional scale. A moire techniques is in itself an optical processing method reducing evaluation time which is advantageous when real-time response is desired from hybrid metrological systems. The moire evaluation is performed via a dynamical digital memory that executes arithmetic operations on two frames temporally in sequence, at TV rate. These characteristics of the moire evaluation techniques can be implemented on a real-time holographic (or speckle based) hybrid system with great practical advantage for dynamical studies.

  14. Self-interference polarization holographic imaging of a three-dimensional incoherent scene

    NASA Astrophysics Data System (ADS)

    Zhu, Ziyi; Shi, Zhimin

    2016-08-01

    We present a self-interference polarization holographic imaging (Si-Phi) technique to capture the three-dimensional information of an incoherent scene in a single shot. The light from the scene is modulated by a polarization-dependent lens, and a complex-valued polarization hologram is obtained by measuring directly the polarization profile of the light at the detection plane. Using a backward-propagating Green's function, we can numerically retrieve the transverse intensity profile of the scene at any desired focus plane. We demonstrate experimentally our Si-Phi technique by imaging, in real time, three-dimensional mimicked incoherent scenes created by a fast spatial light modulator.

  15. A preconditioned dual–primal finite element tearing and interconnecting method for solving three-dimensional time-harmonic Maxwell's equations

    SciTech Connect

    Xue, Ming-Feng; Jin, Jian-Ming

    2014-10-01

    A new preconditioned dual–primal nonoverlapping domain decomposition method is proposed for the finite element solution of three-dimensional large-scale electromagnetic problems. With the aid of two Lagrange multipliers, the new method converts the original volumetric problem to a surface problem by using a higher-order transmission condition at the subdomain interfaces to significantly improve the convergence of the iterative solution of the global interface equation. Similar to the previous version, a global coarse problem related to the degrees of freedom at the subdomain corner edges is formulated to propagate the residual error to the whole computational domain at each iteration, which further increases the rate of convergence. In addition, a fully algebraic preconditioner based on matrix splitting is constructed to make the proposed domain decomposition method even more robust and scalable. Perfectly matched layers (PMLs) are considered for the boundary truncation when solving open-region problems. The influence of the PML truncation on the convergence performance is investigated by examining the convergence of the transmission condition for an interface inside the PML. Numerical examples including wave propagation and antenna radiation problems truncated with PMLs are presented to demonstrate the validity and the capability of this method.

  16. On Using Taylor's Hypothesis for Three-Dimensional Mixing Layers

    NASA Technical Reports Server (NTRS)

    LeBoeuf, Richard L.; Mehta, Rabindra D.

    1995-01-01

    In the present study, errors in using Taylor's hypothesis to transform measurements obtained in a temporal (or phase) frame onto a spatial one were evaluated. For the first time, phase-averaged ('real') spanwise and streamwise vorticity data measured on a three-dimensional grid were compared directly to those obtained using Taylor's hypothesis. The results show that even the qualitative features of the spanwise and streamwise vorticity distributions given by the two techniques can be very different. This is particularly true in the region of the spanwise roller pairing. The phase-averaged spanwise and streamwise peak vorticity levels given by Taylor's hypothesis are typically lower (by up to 40%) compared to the real measurements.

  17. Three-dimensional coil inductor

    DOEpatents

    Bernhardt, Anthony F.; Malba, Vincent

    2002-01-01

    A three-dimensional coil inductor is disclosed. The inductor includes a substrate; a set of lower electrically conductive traces positioned on the substrate; a core placed over the lower traces; a set of side electrically conductive traces laid on the core and the lower traces; and a set of upper electrically conductive traces attached to the side traces so as to form the inductor. Fabrication of the inductor includes the steps of forming a set of lower traces on a substrate; positioning a core over the lower traces; forming a set of side traces on the core; connecting the side traces to the lower traces; forming a set of upper traces on the core; and connecting the upper traces to the side traces so as to form a coil structure.

  18. Three-dimensional aromatic networks.

    PubMed

    Toyota, Shinji; Iwanaga, Tetsuo

    2014-01-01

    Three-dimensional (3D) networks consisting of aromatic units and linkers are reviewed from various aspects. To understand principles for the construction of such compounds, we generalize the roles of building units, the synthetic approaches, and the classification of networks. As fundamental compounds, cyclophanes with large aromatic units and aromatic macrocycles with linear acetylene linkers are highlighted in terms of transannular interactions between aromatic units, conformational preference, and resolution of chiral derivatives. Polycyclic cage compounds are constructed from building units by linkages via covalent bonds, metal-coordination bonds, or hydrogen bonds. Large cage networks often include a wide range of guest species in their cavity to afford novel inclusion compounds. Topological isomers consisting of two or more macrocycles are formed by cyclization of preorganized species. Some complicated topological networks are constructed by self-assembly of simple building units.

  19. Amplitude interpretation and visualization of three-dimensional reflection data

    SciTech Connect

    Enachescu, M.E. )

    1994-07-01

    Digital recording and processing of modern three-dimensional surveys allow for relative good preservation and correct spatial positioning of seismic reflection amplitude. A four-dimensional seismic reflection field matrix R (x,y,t,A), which can be computer visualized (i.e., real-time interactively rendered, edited, and animated), is now available to the interpreter. The amplitude contains encoded geological information indirectly related to lithologies and reservoir properties. The magnitude of the amplitude depends not only on the acoustic impedance contrast across a boundary, but is also strongly affected by the shape of the reflective boundary. This allows the interpreter to image subtle tectonic and structural elements not obvious on time-structure maps. The use of modern workstations allows for appropriate color coding of the total available amplitude range, routine on-screen time/amplitude extraction, and late display of horizon amplitude maps (horizon slices) or complex amplitude-structure spatial visualization. Stratigraphic, structural, tectonic, fluid distribution, and paleogeographic information are commonly obtained by displaying the amplitude variation A = A(x,y,t) associated with a particular reflective surface or seismic interval. As illustrated with several case histories, traditional structural and stratigraphic interpretation combined with a detailed amplitude study generally greatly enhance extraction of subsurface geological information from a reflection data volume. In the context of three-dimensional seismic surveys, the horizon amplitude map (horizon slice), amplitude attachment to structure and [open quotes]bright clouds[close quotes] displays are very powerful tools available to the interpreter.

  20. Rapid hologram updates for real-time volumetric information displays.

    PubMed

    Munjuluri, Bala; Huebschman, Michael L; Garner, Harold R

    2005-08-20

    We have demonstrated that holograms incorporating changes in three-dimensional (3D) scenes can be recalculated in real time to present dynamic updates on information displays. This approach displays 3D information in a compatible format for fast and reliable interpretation of changes in the 3D scenes. The rapid-update algorithm has been demonstrated by real-time computation and transcription of the holograms to our digital micromirror device hologram projection system for visual validation of the reconstruction. The reported algorithm enables full parallax 1024 x 768 pixel holograms of 3D scenes to be updated at a rate of 0.8 s with a 1.8 GHz personal computer. Volumetric information displays that can enhance reliable data assimilation and decrease reaction times for applications such as air-traffic control, cockpit heads-up displays, mission crew stations, and undersea navigation can benefit from this research.

  1. Real Time Sonic Boom Display

    NASA Technical Reports Server (NTRS)

    Haering, Ed

    2014-01-01

    This presentation will provide general information about sonic boom mitigation technology to the public in order to supply information to potential partners and licensees. The technology is a combination of flight data, atmospheric data and terrain information implemented into a control room real time display for flight planning. This research is currently being performed and as such, any results and conclusions are ongoing.

  2. Real-time high dynamic range laser scanning microscopy.

    PubMed

    Vinegoni, C; Leon Swisher, C; Fumene Feruglio, P; Giedt, R J; Rousso, D L; Stapleton, S; Weissleder, R

    2016-01-01

    In conventional confocal/multiphoton fluorescence microscopy, images are typically acquired under ideal settings and after extensive optimization of parameters for a given structure or feature, often resulting in information loss from other image attributes. To overcome the problem of selective data display, we developed a new method that extends the imaging dynamic range in optical microscopy and improves the signal-to-noise ratio. Here we demonstrate how real-time and sequential high dynamic range microscopy facilitates automated three-dimensional neural segmentation. We address reconstruction and segmentation performance on samples with different size, anatomy and complexity. Finally, in vivo real-time high dynamic range imaging is also demonstrated, making the technique particularly relevant for longitudinal imaging in the presence of physiological motion and/or for quantification of in vivo fast tracer kinetics during functional imaging. PMID:27032979

  3. Real-time high dynamic range laser scanning microscopy

    PubMed Central

    Vinegoni, C.; Leon Swisher, C.; Fumene Feruglio, P.; Giedt, R. J.; Rousso, D. L.; Stapleton, S.; Weissleder, R.

    2016-01-01

    In conventional confocal/multiphoton fluorescence microscopy, images are typically acquired under ideal settings and after extensive optimization of parameters for a given structure or feature, often resulting in information loss from other image attributes. To overcome the problem of selective data display, we developed a new method that extends the imaging dynamic range in optical microscopy and improves the signal-to-noise ratio. Here we demonstrate how real-time and sequential high dynamic range microscopy facilitates automated three-dimensional neural segmentation. We address reconstruction and segmentation performance on samples with different size, anatomy and complexity. Finally, in vivo real-time high dynamic range imaging is also demonstrated, making the technique particularly relevant for longitudinal imaging in the presence of physiological motion and/or for quantification of in vivo fast tracer kinetics during functional imaging. PMID:27032979

  4. Real-time high dynamic range laser scanning microscopy

    NASA Astrophysics Data System (ADS)

    Vinegoni, C.; Leon Swisher, C.; Fumene Feruglio, P.; Giedt, R. J.; Rousso, D. L.; Stapleton, S.; Weissleder, R.

    2016-04-01

    In conventional confocal/multiphoton fluorescence microscopy, images are typically acquired under ideal settings and after extensive optimization of parameters for a given structure or feature, often resulting in information loss from other image attributes. To overcome the problem of selective data display, we developed a new method that extends the imaging dynamic range in optical microscopy and improves the signal-to-noise ratio. Here we demonstrate how real-time and sequential high dynamic range microscopy facilitates automated three-dimensional neural segmentation. We address reconstruction and segmentation performance on samples with different size, anatomy and complexity. Finally, in vivo real-time high dynamic range imaging is also demonstrated, making the technique particularly relevant for longitudinal imaging in the presence of physiological motion and/or for quantification of in vivo fast tracer kinetics during functional imaging.

  5. Real-time stereo generation for surgical vision during minimal invasive robotic surgery

    NASA Astrophysics Data System (ADS)

    Laddi, Amit; Bhardwaj, Vijay; Mahapatra, Prasant; Pankaj, Dinesh; Kumar, Amod

    2016-03-01

    This paper proposes a framework for 3D surgical vision for minimal invasive robotic surgery. It presents an approach for generating the three dimensional view of the in-vivo live surgical procedures from two images captured by very small sized, full resolution camera sensor rig. A pre-processing scheme is employed to enhance the image quality and equalizing the color profile of two images. Polarized Projection using interlacing two images give a smooth and strain free three dimensional view. The algorithm runs in real time with good speed at full HD resolution.

  6. Three dimensional magnetic abacus memory

    NASA Astrophysics Data System (ADS)

    Zhang, Shilei; Zhang, Jingyan; Baker, Alexander A.; Wang, Shouguo; Yu, Guanghua; Hesjedal, Thorsten

    2014-08-01

    Stacking nonvolatile memory cells into a three-dimensional matrix represents a powerful solution for the future of magnetic memory. However, it is technologically challenging to access the data in the storage medium if large numbers of bits are stacked on top of each other. Here we introduce a new type of multilevel, nonvolatile magnetic memory concept, the magnetic abacus. Instead of storing information in individual magnetic layers, thereby having to read out each magnetic layer separately, the magnetic abacus adopts a new encoding scheme. It is inspired by the idea of second quantisation, dealing with the memory state of the entire stack simultaneously. Direct read operations are implemented by measuring the artificially engineered `quantised' Hall voltage, each representing a count of the spin-up and spin-down layers in the stack. This new memory system further allows for both flexible scaling of the system and fast communication among cells. The magnetic abacus provides a promising approach for future nonvolatile 3D magnetic random access memory.

  7. Three dimensional magnetic abacus memory.

    PubMed

    Zhang, ShiLei; Zhang, JingYan; Baker, Alexander A; Wang, ShouGuo; Yu, GuangHua; Hesjedal, Thorsten

    2014-08-22

    Stacking nonvolatile memory cells into a three-dimensional matrix represents a powerful solution for the future of magnetic memory. However, it is technologically challenging to access the data in the storage medium if large numbers of bits are stacked on top of each other. Here we introduce a new type of multilevel, nonvolatile magnetic memory concept, the magnetic abacus. Instead of storing information in individual magnetic layers, thereby having to read out each magnetic layer separately, the magnetic abacus adopts a new encoding scheme. It is inspired by the idea of second quantisation, dealing with the memory state of the entire stack simultaneously. Direct read operations are implemented by measuring the artificially engineered 'quantised' Hall voltage, each representing a count of the spin-up and spin-down layers in the stack. This new memory system further allows for both flexible scaling of the system and fast communication among cells. The magnetic abacus provides a promising approach for future nonvolatile 3D magnetic random access memory.

  8. Three dimensional magnetic abacus memory

    NASA Astrophysics Data System (ADS)

    Zhang, Shilei; Zhang, Jingyan; Baker, Alexander; Wang, Shouguo; Yu, Guanghua; Hesjedal, Thorsten

    2015-03-01

    Stacking nonvolatile memory cells into a three-dimensional matrix represents a powerful solution for the future of magnetic memory. However, it is technologically challenging to access the individual data in the storage medium if large numbers of bits are stacked on top of each other. Here we introduce a new type of multilevel, nonvolatile magnetic memory concept, the magnetic abacus. Instead of storing information in individual magnetic layers, thereby having to read out each magnetic layer separately, the magnetic abacus adopts a new encoding scheme which envisages a classical abacus with the beads operated by electron spins. It is inspired by the idea of second quantization, dealing with the memory state of the entire stack simultaneously. Direct read operations are implemented by measuring the artificially engineered `quantized' Hall voltage, representing a count of the spin-up and spin-down layers in the stack. This concept of `second quantization of memory' realizes the 3D memory architecture with superior reading and operation efficiency, thus is a promising approach for future nonvolatile magnetic random access memory.

  9. True three-dimensional camera

    NASA Astrophysics Data System (ADS)

    Kornreich, Philipp; Farell, Bart

    2013-01-01

    An imager that can measure the distance from each pixel to the point on the object that is in focus at the pixel is described. This is accomplished by short photo-conducting lightguides at each pixel. In the eye the rods and cones are the fiber-like lightguides. The device uses ambient light that is only coherent in spherical shell-shaped light packets of thickness of one coherence length. Modern semiconductor technology permits the construction of lightguides shorter than a coherence length of ambient light. Each of the frequency components of the broad band light arriving at a pixel has a phase proportional to the distance from an object point to its image pixel. Light frequency components in the packet arriving at a pixel through a convex lens add constructively only if the light comes from the object point in focus at this pixel. The light in packets from all other object points cancels. Thus the pixel receives light from one object point only. The lightguide has contacts along its length. The lightguide charge carriers are generated by the light patterns. These light patterns, and thus the photocurrent, shift in response to the phase of the input signal. Thus, the photocurrent is a function of the distance from the pixel to its object point. Applications include autonomous vehicle navigation and robotic vision. Another application is a crude teleportation system consisting of a camera and a three-dimensional printer at a remote location.

  10. The current status of three-dimensional ultrasonography in gynaecology.

    PubMed

    Ong, Chiou Li

    2016-01-01

    Ultrasonography (US) is the most recent cross-sectional imaging modality to acquire three-dimensional (3D) capabilities. The reconstruction of volumetric US data for multiplanar display took a significantly longer time to develop in comparison with computed tomography and magnetic resonance imaging. The current equipment for 3D-US is capable of producing high-resolution images in three different planes, including real-time surface-rendered images. The use of 3D-US in gynaecology was accelerated through the development of the endovaginal volume transducer, which allows the automated acquisition of volumetric US data. Although initially considered an adjunct to two-dimensional US, 3D-US is now the imaging modality of choice for the assessment of Müllerian duct anomalies and the location of intrauterine devices.

  11. Real time psychrometric data collection

    SciTech Connect

    McDaniel, K.H.

    1996-12-31

    Eight Mine Weather Stations (MWS) installed at the Waste Isolation Pilot Plant (WIPP) to monitor the underground ventilation system are helping to simulate real-time ventilation scenarios. Seasonal weather extremes can result in variations of Natural Ventilation Pressure (NVP) which can significantly effect the ventilation system. The eight MWS(s) (which previously collected and stored temperature, barometric pressure and relative humidity data for subsequent NVP calculations) were upgraded to provide continuous real-time data to the site wide Central monitoring System. This data can now be utilized by the ventilation engineer to create realtime ventilation simulations and trends which assist in the prediction and mitigation of NVP and psychrometric related events.

  12. Construction of Three Dimensional Solutions for the Maxwell Equations

    NASA Technical Reports Server (NTRS)

    Yefet, A.; Turkel, E.

    1998-01-01

    We consider numerical solutions for the three dimensional time dependent Maxwell equations. We construct a fourth order accurate compact implicit scheme and compare it to the Yee scheme for free space in a box.

  13. Real-time tritium imaging

    SciTech Connect

    Malinowski, M.E.

    1981-09-15

    A real-time image of a tritium-containing titanium film has been made by detecting the secondary electrons produced by tritium ..beta.. decay with a simple two-element electrostatic lens and microchannel plate image intensifier. The obtained image indicates that a resolution of better than 100 ..mu..m is currently obtainable and suggests that image magnification to enhance resolution should be possible.

  14. Horizontal biases in rats' use of three-dimensional space.

    PubMed

    Jovalekic, Aleksandar; Hayman, Robin; Becares, Natalia; Reid, Harry; Thomas, George; Wilson, Jonathan; Jeffery, Kate

    2011-09-23

    Rodent spatial cognition studies allow links to be made between neural and behavioural phenomena, and much is now known about the encoding and use of horizontal space. However, the real world is three dimensional, providing cognitive challenges that have yet to be explored. Motivated by neural findings suggesting weaker encoding of vertical than horizontal space, we examined whether rats show a similar behavioural anisotropy when distributing their time freely between vertical and horizontal movements. We found that in two- or three-dimensional environments with a vertical dimension, rats showed a prioritization of horizontal over vertical movements in both foraging and detour tasks. In the foraging tasks, the animals executed more horizontal than vertical movements and adopted a "layer strategy" in which food was collected from one horizontal level before moving to the next. In the detour tasks, rats preferred the routes that allowed them to execute the horizontal leg first. We suggest three possible reasons for this behavioural bias. First, as suggested by Grobety and Schenk, it allows minimisation of energy expenditure, inasmuch as costly vertical movements are minimised. Second, it may be a manifestation of the temporal discounting of effort, in which animals value delayed effort as less costly than immediate effort. Finally, it may be that at the neural level rats encode the vertical dimension less precisely, and thus prefer to bias their movements in the more accurately encoded horizontal dimension. We suggest that all three factors are related, and all play a part.

  15. Real-time exploitation system

    NASA Astrophysics Data System (ADS)

    Riedel, Richard D.

    1998-11-01

    The proliferation and technology advances of digital sensors for reconnaissance imaging require a commensurate increase in the productivity of ground-based exploitation system to process the increased volume of remotely-sensed data. Systems to support this level of production, themselves, must have significantly reduced development and life-cycle costs from previously installed systems. For cost, growth, and integration advantages, reconnaissance exploitation systems should be designed to maximize Commercial-Off-The-Shelf (COTS) hardware and software. As an example, the Real-Time Exploitation System is a state-of-the-art system for photo interpretation and exploitation of real-time digital reconnaissance imagery. Using COTS hardware, the system is able to receive imagery at rates greater than 80 Mpixels/sec; perform detailed interpretation, exploitation and report generation, and; disseminate reports to intelligence users over secure networks. New technologies have been applied in workflow management, database management, and user interfaces to provide the image analyst with superior analysis tools and access to other intelligence data sources. Photogrammetric functions are also provided for monoscopic and stereoscopic imagery. These functions provide greater geographic accuracy than is achievable in most reconnaissance exploitation systems. The Real-Time Exploitation System significantly reduces timelines for the analysis and report generation process, and significantly increases the quality and accuracy of reports.

  16. Three-dimensional surgical simulation.

    PubMed

    Cevidanes, Lucia H C; Tucker, Scott; Styner, Martin; Kim, Hyungmin; Chapuis, Jonas; Reyes, Mauricio; Proffit, William; Turvey, Timothy; Jaskolka, Michael

    2010-09-01

    In this article, we discuss the development of methods for computer-aided jaw surgery, which allows us to incorporate the high level of precision necessary for transferring virtual plans into the operating room. We also present a complete computer-aided surgery system developed in close collaboration with surgeons. Surgery planning and simulation include construction of 3-dimensional surface models from cone-beam computed tomography, dynamic cephalometry, semiautomatic mirroring, interactive cutting of bone, and bony segment repositioning. A virtual setup can be used to manufacture positioning splints for intraoperative guidance. The system provides further intraoperative assistance with a computer display showing jaw positions and 3-dimensional positioning guides updated in real time during the surgical procedure. The computer-aided surgery system aids in dealing with complex cases with benefits for the patient, with surgical practice, and for orthodontic finishing. Advanced software tools for diagnosis and treatment planning allow preparation of detailed operative plans, osteotomy repositioning, bone reconstructions, surgical resident training, and assessing the difficulties of the surgical procedures before the surgery. Computer-aided surgery can make the elaboration of the surgical plan a more flexible process, increase the level of detail and accuracy of the plan, yield higher operative precision and control, and enhance documentation of cases.

  17. Abstraction Planning in Real Time

    NASA Technical Reports Server (NTRS)

    Washington, Richard

    1994-01-01

    When a planning agent works in a complex, real-world domain, it is unable to plan for and store all possible contingencies and problem situations ahead of time. The agent needs to be able to fall back on an ability to construct plans at run time under time constraints. This thesis presents a method for planning at run time that incrementally builds up plans at multiple levels of abstraction. The plans are continually updated by information from the world, allowing the planner to adjust its plan to a changing world during the planning process. All the information is represented over intervals of time, allowing the planner to reason about durations, deadlines, and delays within its plan. In addition to the method, the thesis presents a formal model of the planning process and uses the model to investigate planning strategies. The method has been implemented, and experiments have been run to validate the overall approach and the theoretical model.

  18. Real-time flutter analysis

    NASA Technical Reports Server (NTRS)

    Walker, R.; Gupta, N.

    1984-01-01

    The important algorithm issues necessary to achieve a real time flutter monitoring system; namely, the guidelines for choosing appropriate model forms, reduction of the parameter convergence transient, handling multiple modes, the effect of over parameterization, and estimate accuracy predictions, both online and for experiment design are addressed. An approach for efficiently computing continuous-time flutter parameter Cramer-Rao estimate error bounds were developed. This enables a convincing comparison of theoretical and simulation results, as well as offline studies in preparation for a flight test. Theoretical predictions, simulation and flight test results from the NASA Drones for Aerodynamic and Structural Test (DAST) Program are compared.

  19. Three-dimensional aerodynamic shape optimization using discrete sensitivity analysis

    NASA Technical Reports Server (NTRS)

    Burgreen, Gregory W.

    1995-01-01

    An aerodynamic shape optimization procedure based on discrete sensitivity analysis is extended to treat three-dimensional geometries. The function of sensitivity analysis is to directly couple computational fluid dynamics (CFD) with numerical optimization techniques, which facilitates the construction of efficient direct-design methods. The development of a practical three-dimensional design procedures entails many challenges, such as: (1) the demand for significant efficiency improvements over current design methods; (2) a general and flexible three-dimensional surface representation; and (3) the efficient solution of very large systems of linear algebraic equations. It is demonstrated that each of these challenges is overcome by: (1) employing fully implicit (Newton) methods for the CFD analyses; (2) adopting a Bezier-Bernstein polynomial parameterization of two- and three-dimensional surfaces; and (3) using preconditioned conjugate gradient-like linear system solvers. Whereas each of these extensions independently yields an improvement in computational efficiency, the combined effect of implementing all the extensions simultaneously results in a significant factor of 50 decrease in computational time and a factor of eight reduction in memory over the most efficient design strategies in current use. The new aerodynamic shape optimization procedure is demonstrated in the design of both two- and three-dimensional inviscid aerodynamic problems including a two-dimensional supersonic internal/external nozzle, two-dimensional transonic airfoils (resulting in supercritical shapes), three-dimensional transport wings, and three-dimensional supersonic delta wings. Each design application results in realistic and useful optimized shapes.

  20. Cosmic Atlas: A Real-Time Universe Simulation

    NASA Astrophysics Data System (ADS)

    Yu, K. C.; Jenkins, N. E.

    2004-05-01

    Cosmic Atlas is a software program produced at the Denver Museum of Nature & Science to generate real-time digital content for the Museum's Gates Planetarium. Created by in-house staff, Cosmic Atlas is designed to be scientifically accurate, flexible, easily updated to stay current with new discoveries, and portable to multiple platforms. It is currently developed using desktop computers running a Linux OS, and is also installed on a multi-graphics pipe SGI visualization computer running the IRIX OS in the Gates Planetarium. The software can be used in real-time presentations via traditional ``star talks'' and classes, but can also be used to devise flightpaths, perform timeline-based editing, play back flightpaths in real-time, and save out image renders for creating video files to be shown on additional playback systems. The first version of the program is meant to replicate the functionality of a traditional optical-mechanical star ball, and hence creates a replica of the night time sky, with constellations, deep sky objects, and didactic information and grids. The Solar System is a realistic, three-dimensional, navigable simulation, updated with the latest moon and minor planet discoveries, and with motions over time determined by a customized orrery. Additional modules can show traditional astronomical imagery, including an application for loading in FITS files to create three-color composites. A three-dimensional model of the Milky Way is in development, populated with HIPPARCOS stars for the local galactic neighborhood, and with molecular clouds constructed from large-scale CO survey data; more distant regions are filled with statistically generated stellar and interstellar medium distributions.

  1. Three-dimensional laser-assisted processing of bioceramics

    NASA Astrophysics Data System (ADS)

    Comesaña, R.; Lusquiños, F.; del Val, J.; Malot, T.; Riveiro, A.; Quintero, F.; Boutinguiza, M.; Aubry, P.; Pou, J.

    The study of calcium phosphate bioceramics processing by rapid prototyping based on laser cladding was tackled in this work. This technique shows a great potential to provide a three-dimensional tailored implant adapted to the specific problem of each patient. Working window to produce stable geometrical features and repeatable microstructures was established by real time process monitoring and characterization of the processed material. The relationships between the processing parameters and the obtained properties are discussed, in addition to the biological behaviour of the produced parts. The obtained calcium phosphate phases (oxyapatite, tricalcium phosphate, tetracalcium phosphate and amorphous calcium phosphate) are found to favorably influence the degradability of the precursor hydroxyapatite in Tris-HCl buffer which is a good sign of the favorable behavior of this type of materials when implanted 'in vivo'.

  2. Three-dimensional television: a broadcaster's perspective

    NASA Astrophysics Data System (ADS)

    Jolly, S. J. E.; Armstrong, M.; Salmon, R. A.

    2009-02-01

    The recent resurgence of interest in the stereoscopic cinema and the increasing availability to the consumer of stereoscopic televisions and computer displays are leading broadcasters to consider, once again, the feasibility of stereoscopic broadcasting. High Definition Television is now widely deployed, and the R&D departments of broadcasters and consumer electronics manufacturers are starting to plan future enhancements to the experience of television. Improving the perception of depth via stereoscopy is a strong candidate technology. In this paper we will consider the challenges associated with the production, transmission and display of different forms of "three-dimensional" television. We will explore options available to a broadcaster wishing to start a 3D service using the technologies available at the present time, and consider how they could be improved to enable many more television programmes to be recorded and transmitted in a 3D-compatible form, paying particular attention to scenarios such as live broadcasting, where the workflows developed for the stereoscopic cinema are inapplicable. We will also consider the opportunities available for broadcasters to reach audiences with "three-dimensional" content via other media in the near future: for example, distributing content via the existing stereoscopic cinema network, or over the Internet to owners of stereoscopic computer displays.

  3. Abstraction Planning in Real Time

    NASA Technical Reports Server (NTRS)

    Washington, R.

    1994-01-01

    When a planning agent works in a complex, real-world domain, it is unable to plan for and store all possible contingencies and problem situations ahead of time. This thesis presents a method for planning a run time that incrementally builds up plans at multiple levels of abstraction. The plans are continually updated by information from the world, allowing the planner to adjust its plan to a changing world during the planning process. All the information is represented over intervals of time, allowing the planner to reason about durations, deadlines, and delays within its plan. In addition to the method, the thesis presents a formal model of the planning process and uses the model to investigate planning strategies.

  4. Real-time streamflow conditions

    USGS Publications Warehouse

    Graczyk, David J.; Gebert, Warren A.

    1996-01-01

    Would you like to know streamflow conditions before you go fishing in Wisconsin or in more distant locations? Real-time streamflow data throughout Wisconsin and the United States are available on the Internet from the U.S. Geological Survey. You can see if the stream you are interested in fishing is high due to recent rain or low because of an extended dry spell. Flow conditions at more than 100 stream-gaging stations located throughout Wisconsin can be viewed by accessing the Wisconsin District Home Page at: http://wwwdwimdn.er.usgs.gov

  5. Real time infrared aerosol analyzer

    DOEpatents

    Johnson, Stanley A.; Reedy, Gerald T.; Kumar, Romesh

    1990-01-01

    Apparatus for analyzing aerosols in essentially real time includes a virtual impactor which separates coarse particles from fine and ultrafine particles in an aerosol sample. The coarse and ultrafine particles are captured in PTFE filters, and the fine particles impact onto an internal light reflection element. The composition and quantity of the particles on the PTFE filter and on the internal reflection element are measured by alternately passing infrared light through the filter and the internal light reflection element, and analyzing the light through infrared spectrophotometry to identify the particles in the sample.

  6. Radial Stellar Pulsation and Three-dimensional Convection. IV. Full Amplitude Three-dimensional Solutions

    NASA Astrophysics Data System (ADS)

    Geroux, Christopher M.; Deupree, Robert G.

    2015-02-01

    Three-dimensional hydrodynamic simulations of full amplitude RR Lyrae stars have been computed for several models across the instability strip. The three-dimensional nature of the calculations allows convection to be treated without reference to a phenomenological approach such as the local mixing length theory. Specifically, the time-dependent interaction of large-scale eddies and radial pulsation is controlled by conservation laws, while the effects of smaller convective eddies are simulated by an eddy viscosity model. The light amplitudes for these calculations are quite similar to those of our previous two-dimensional calculations in the middle of the instability strip, but somewhat lower near the red edge, the fundamental blue edge, and for the one first overtone model we computed. The time-dependent interaction between the radial pulsation and the convective energy transport is essentially the same in three dimensions as it is in two dimensions. There are some differences between the light curves of the two- and three-dimensional simulations, particularly during decreasing light. Reasons for the differences, both numerical and physical, are explored.

  7. RADIAL STELLAR PULSATION AND THREE-DIMENSIONAL CONVECTION. IV. FULL AMPLITUDE THREE-DIMENSIONAL SOLUTIONS

    SciTech Connect

    Geroux, Christopher M.; Deupree, Robert G.

    2015-02-10

    Three-dimensional hydrodynamic simulations of full amplitude RR Lyrae stars have been computed for several models across the instability strip. The three-dimensional nature of the calculations allows convection to be treated without reference to a phenomenological approach such as the local mixing length theory. Specifically, the time-dependent interaction of large-scale eddies and radial pulsation is controlled by conservation laws, while the effects of smaller convective eddies are simulated by an eddy viscosity model. The light amplitudes for these calculations are quite similar to those of our previous two-dimensional calculations in the middle of the instability strip, but somewhat lower near the red edge, the fundamental blue edge, and for the one first overtone model we computed. The time-dependent interaction between the radial pulsation and the convective energy transport is essentially the same in three dimensions as it is in two dimensions. There are some differences between the light curves of the two- and three-dimensional simulations, particularly during decreasing light. Reasons for the differences, both numerical and physical, are explored.

  8. Real time analysis under EDS

    NASA Astrophysics Data System (ADS)

    Schneberk, D.

    1985-07-01

    The analysis component of the Enrichment Diagnostic System (EDS) developed for the Atomic Vapor Laser Isotope Separation Program (AVLIS) at Lawrence Livermore National Laboratory (LLNL) is described. Four different types of analysis are performed on data acquired through EDS: (1) absorption spectroscopy on laser-generated spectral lines, (2) mass spectrometer analysis, (3) general purpose waveform analysis, and (4) separation performance calculations. The information produced from this data includes: measures of particle density and velocity, partial pressures of residual gases, and overall measures of isotope enrichment. The analysis component supports a variety of real-time modeling tasks, a means for broadcasting data to other nodes, and a great degree of flexibility for tailoring computations to the exact needs of the process. A particular data base structure and program flow is common to all types of analysis. Key elements of the analysis component are: (1) a fast access data base which can configure all types of analysis, (2) a selected set of analysis routines, (3) a general purpose data manipulation and graphics package for the results of real time analysis.

  9. Real-time face tracking

    NASA Astrophysics Data System (ADS)

    Liang, Yufeng; Wilder, Joseph

    1998-10-01

    A real-time face tracker is presented in this paper. The system has achieved 15 frames/second tracking using a Pentium 200 PC with a Datacube MaxPCI image processing board and a Panasonic RGB color camera. It tracks human faces in the camera's field of view while people move freely. A stochastic model to characterize the skin color distribution of human skin is used to segment the face and other skin areas from the background. Median filtering is then used to clean up the background noise. Geometric constraints are applied to the segmented image to extract the face from the background. To reduce computation and achieve real-time tracking, 1D projections (horizontal and vertical) of the image are analyzed instead of the 2D image. Run-length- encoding and frequency domain analysis algorithms are used to separate faces from other skin-like blobs. The system is robust to illumination intensity variations and different skin colors. It can be applied to many human-computer interaction applications such as sound locating, lip- reading, gaze tracking and face recognition.

  10. Magnetic Resonance Angiography in the Diagnosis of Cerebral Arteriovenous Malformation and Dural Arteriovenous Fistulas: Comparison of Time-Resolved Magnetic Resonance Angiography and Three Dimensional Time-of-Flight Magnetic Resonance Angiography

    PubMed Central

    Cheng, Yu-Ching; Chen, Hung-Chieh; Wu, Chen-Hao; Wu, Yi-Ying; Sun, Ming-His; Chen, Wen-Hsien; Chai, Jyh-Wen; Chi-Chang Chen, Clayton

    2016-01-01

    Background Traditional digital subtraction angiography (DSA) is currently the gold standard diagnostic method for the diagnosis and evaluation of cerebral arteriovenous malformation (AVM) and dural arteriovenous fistulas (dAVF). Objectives The aim of this study was to analyze different less invasive magnetic resonance angiography (MRA) images, time-resolved MRA (TR-MRA) and three-dimensional time-of-flight MRA (3D TOF MRA) to identify their diagnostic accuracy and to determine which approach is most similar to DSA. Patients and Methods A total of 41 patients with AVM and dAVF at their initial evaluation or follow-up after treatment were recruited in this study. We applied time-resolved angiography using keyhole (4D-TRAK) MRA to perform TR-MRA and 3D TOF MRA examinations simultaneously followed by DSA, which was considered as a standard reference. Two experienced neuroradiologists reviewed the images to compare the diagnostic accuracy, arterial feeder and venous drainage between these two MRA images. Inter-observer agreement for different MRA images was assessed by Kappa coefficient and the differences of diagnostic accuracy between MRA images were evaluated by the Wilcoxon rank sum test. Results Almost all vascular lesions (92.68%) were correctly diagnosed using 4D-TRAK MRA. However, 3D TOF MRA only diagnosed 26 patients (63.41%) accurately. There were statistically significant differences regarding lesion diagnostic accuracy (P = 0.008) and venous drainage identification (P < 0.0001) between 4D-TRAK MRA and 3D TOF MRA. The results indicate that 4D-TRAK MRA is superior to 3D TOF MRA in the assessment of lesions. Conclusion Compared with 3D TOF MRA, 4D-TRAK MRA proved to be a more reliable screening modality and follow-up method for the diagnosis of cerebral AVM and dAVF.

  11. Magnetic Resonance Angiography in the Diagnosis of Cerebral Arteriovenous Malformation and Dural Arteriovenous Fistulas: Comparison of Time-Resolved Magnetic Resonance Angiography and Three Dimensional Time-of-Flight Magnetic Resonance Angiography

    PubMed Central

    Cheng, Yu-Ching; Chen, Hung-Chieh; Wu, Chen-Hao; Wu, Yi-Ying; Sun, Ming-His; Chen, Wen-Hsien; Chai, Jyh-Wen; Chi-Chang Chen, Clayton

    2016-01-01

    Background Traditional digital subtraction angiography (DSA) is currently the gold standard diagnostic method for the diagnosis and evaluation of cerebral arteriovenous malformation (AVM) and dural arteriovenous fistulas (dAVF). Objectives The aim of this study was to analyze different less invasive magnetic resonance angiography (MRA) images, time-resolved MRA (TR-MRA) and three-dimensional time-of-flight MRA (3D TOF MRA) to identify their diagnostic accuracy and to determine which approach is most similar to DSA. Patients and Methods A total of 41 patients with AVM and dAVF at their initial evaluation or follow-up after treatment were recruited in this study. We applied time-resolved angiography using keyhole (4D-TRAK) MRA to perform TR-MRA and 3D TOF MRA examinations simultaneously followed by DSA, which was considered as a standard reference. Two experienced neuroradiologists reviewed the images to compare the diagnostic accuracy, arterial feeder and venous drainage between these two MRA images. Inter-observer agreement for different MRA images was assessed by Kappa coefficient and the differences of diagnostic accuracy between MRA images were evaluated by the Wilcoxon rank sum test. Results Almost all vascular lesions (92.68%) were correctly diagnosed using 4D-TRAK MRA. However, 3D TOF MRA only diagnosed 26 patients (63.41%) accurately. There were statistically significant differences regarding lesion diagnostic accuracy (P = 0.008) and venous drainage identification (P < 0.0001) between 4D-TRAK MRA and 3D TOF MRA. The results indicate that 4D-TRAK MRA is superior to 3D TOF MRA in the assessment of lesions. Conclusion Compared with 3D TOF MRA, 4D-TRAK MRA proved to be a more reliable screening modality and follow-up method for the diagnosis of cerebral AVM and dAVF. PMID:27679690

  12. Three-dimensional efficient dispersive alternating-direction-implicit finite-difference time-domain algorithm using a quadratic complex rational function.

    PubMed

    Kim, E-K; Ha, S-G; Lee, J; Park, Y B; Jung, K-Y

    2015-01-26

    Efficient unconditionally stable FDTD method is developed for the electromagnetic analysis of dispersive media. Toward this purpose, a quadratic complex rational function (QCRF) dispersion model is applied to the alternating-direction-implicit finite-difference time-domain (ADI-FDTD) method. The 3-D update equations of QCRF-ADI-FDTD are derived using Maxwell's curl equations and the constitutive relation. The periodic boundary condition of QCRF-ADI-FDTD is discussed in detail. A 3-D numerical example shows that the time-step size can be increased by the proposed QCRF-ADI-FDTD beyond the Courant-Friedrich-Levy (CFL) number, without numerical instability. It is observed that, for refined computational cells, the computational time of QCRF-ADI-FDTD is reduced to 28.08 % of QCRF-FDTD, while the L2 relative error norm of a field distribution is 6.92 %.

  13. Real-time flood forecasting

    USGS Publications Warehouse

    Lai, C.; Tsay, T.-K.; Chien, C.-H.; Wu, I.-L.

    2009-01-01

    Researchers at the Hydroinformatic Research and Development Team (HIRDT) of the National Taiwan University undertook a project to create a real time flood forecasting model, with an aim to predict the current in the Tamsui River Basin. The model was designed based on deterministic approach with mathematic modeling of complex phenomenon, and specific parameter values operated to produce a discrete result. The project also devised a rainfall-stage model that relates the rate of rainfall upland directly to the change of the state of river, and is further related to another typhoon-rainfall model. The geographic information system (GIS) data, based on precise contour model of the terrain, estimate the regions that were perilous to flooding. The HIRDT, in response to the project's progress, also devoted their application of a deterministic model to unsteady flow of thermodynamics to help predict river authorities issue timely warnings and take other emergency measures.

  14. Sixty-four-slice CT angiography to determine the three dimensional relationships of vascular and soft tissue wounds in lower extremity war time injuries.

    PubMed

    Smith, Jennifer M; Fox, Charles J; Brazaitis, Michael P; Via, Kathy; Garcia, Roman; Feuerstein, Irwin M

    2010-01-01

    This article analyzes the use and benefits of the 64-slice CT scanner in determining the 3D relationships of vascular and soft tissue wounds in lower extremity war time injuries. A brief overview of CT scanning is given as well as the techniques used to produce the images needed for diagnosis. The series follows two similar cases of war time injury patients at the Walter Reed Army Medical Center. The first case is a 30-year-old active duty male, who presented with multiple trauma from a motor vehicle accident because of an improvised explosive device (IED) blast, sustaining substantial lower extremity injuries. The second case is a 34-year-old active duty male, who presented with multiple trauma blast injuries. Both cases were of interest because the vasculature was found to be very close to the surface of the wound, which put the arteries at risk for rupture and for iatrogenic injury during repeated debridements.

  15. An ensemble Kalman filter approach to identify the hydraulic conductivity spatial distribution from electrical resistivity tomography time-lapse monitoring of three-dimensional tracer test experiments

    NASA Astrophysics Data System (ADS)

    Camporese, M.; Cassiani, G.; Deiana, R.; Perri, M. T.; Salandin, P.

    2012-04-01

    An approach based on the Lagrangian formulation of transport and the ensemble Kalman filter (EnKF) is applied to assess the spatial distribution of hydraulic conductivity K by assimilating time-lapse cross-hole electrical resistivity tomography (ERT) images generated for a synthetic tracer test in a heterogeneous aquifer. Assuming that the solute spreads as a passive tracer, for high Peclet numbers the spatial moments of the evolving plume are dominated by the spatial distribution of the hydraulic conductivity. The assimilation of the electrical conductivity 4D images allows updating both the hydrological state in terms of solute concentration and the spatial distribution of K. Thus, delineation of the tracer plume and estimation of the aquifer heterogeneity at the local scale can be achieved at the same time by means of this interpretation of time-lapse electrical images from tracer tests. We assess the impact on the performance of the hydrological inversion of the uncertainty inherently affecting ERT inversions in terms of tracer concentration and the choice of the prior statistics of K. The results show that realistic ERT images can be integrated into a hydrological model even within an uncoupled inverse modeling framework, the reconstruction of the hydraulic conductivity spatial distribution being satisfactory in the portion of the domain directly covered by the passage of the tracer. Aside from the issues commonly affecting inverse models, the proposed approach is subject to the problem of the filter inbreeding and the retrieval performance is sensitive to the choice of K prior geostatistical parameters.

  16. Dental Implant Placement using C-arm CT Real Time Imaging System: A Case Report.

    PubMed

    Rajkumar, B; Boruah, Lalit C; Thind, Amandeep; Jain, Gaurav; Gupta, Shilpi

    2014-12-01

    C-arm computed tomography (CT) is a new and innovative imaging technique. In combination with two-dimensional fluoroscopic or radiographic imaging, information provided by three-dimensional C-arm real time imaging can be valuable for therapy planning, guidance and outcome assessment in dental implant placement. This paper reports a case of two dental implant placement using Artis zee C-arm CT system first time in field of implantology.

  17. Two-dimensional and three-dimensional dynamic imaging of live biofilms in a microchannel by time-of-flight secondary ion mass spectrometry

    SciTech Connect

    Hua, Xin; Marshall, Matthew J.; Xiong, Yijia; Ma, Xiang; Zhou, Yufan; Tucker, Abigail E.; Zhu, Zihua; Liu, Songqin; Yu, Xiao-Ying

    2015-05-01

    A vacuum compatible microfluidic reactor, SALVI (System for Analysis at the Liquid Vacuum Interface) was employed for in situ chemical imaging of live biofilms using time-of-flight secondary ion mass spectrometry (ToF-SIMS). Depth profiling by sputtering materials in sequential layers resulted in live biofilm spatial chemical mapping. 2D images were reconstructed to report the first 3D images of hydrated biofilm elucidating spatial and chemical heterogeneity. 2D image principal component analysis (PCA) was conducted among biofilms at different locations in the microchannel. Our approach directly visualized spatial and chemical heterogeneity within the living biofilm by dynamic liquid ToF-SIMS.

  18. Autonomous Real Time Requirements Tracing

    NASA Technical Reports Server (NTRS)

    Plattsmier, George; Stetson, Howard

    2014-01-01

    One of the more challenging aspects of software development is the ability to verify and validate the functional software requirements dictated by the Software Requirements Specification (SRS) and the Software Detail Design (SDD). Insuring the software has achieved the intended requirements is the responsibility of the Software Quality team and the Software Test team. The utilization of Timeliner-TLX(sup TM) Auto- Procedures for relocating ground operations positions to ISS automated on-board operations has begun the transition that would be required for manned deep space missions with minimal crew requirements. This transition also moves the auto-procedures from the procedure realm into the flight software arena and as such the operational requirements and testing will be more structured and rigorous. The autoprocedures would be required to meet NASA software standards as specified in the Software Safety Standard (NASASTD- 8719), the Software Engineering Requirements (NPR 7150), the Software Assurance Standard (NASA-STD-8739) and also the Human Rating Requirements (NPR-8705). The Autonomous Fluid Transfer System (AFTS) test-bed utilizes the Timeliner-TLX(sup TM) Language for development of autonomous command and control software. The Timeliner-TLX(sup TM) system has the unique feature of providing the current line of the statement in execution during real-time execution of the software. The feature of execution line number internal reporting unlocks the capability of monitoring the execution autonomously by use of a companion Timeliner-TLX(sup TM) sequence as the line number reporting is embedded inside the Timeliner-TLX(sup TM) execution engine. This negates I/O processing of this type data as the line number status of executing sequences is built-in as a function reference. This paper will outline the design and capabilities of the AFTS Autonomous Requirements Tracker, which traces and logs SRS requirements as they are being met during real-time execution of the

  19. Autonomous Real Time Requirements Tracing

    NASA Technical Reports Server (NTRS)

    Plattsmier, George I.; Stetson, Howard K.

    2014-01-01

    One of the more challenging aspects of software development is the ability to verify and validate the functional software requirements dictated by the Software Requirements Specification (SRS) and the Software Detail Design (SDD). Insuring the software has achieved the intended requirements is the responsibility of the Software Quality team and the Software Test team. The utilization of Timeliner-TLX(sup TM) Auto-Procedures for relocating ground operations positions to ISS automated on-board operations has begun the transition that would be required for manned deep space missions with minimal crew requirements. This transition also moves the auto-procedures from the procedure realm into the flight software arena and as such the operational requirements and testing will be more structured and rigorous. The autoprocedures would be required to meet NASA software standards as specified in the Software Safety Standard (NASASTD- 8719), the Software Engineering Requirements (NPR 7150), the Software Assurance Standard (NASA-STD-8739) and also the Human Rating Requirements (NPR-8705). The Autonomous Fluid Transfer System (AFTS) test-bed utilizes the Timeliner-TLX(sup TM) Language for development of autonomous command and control software. The Timeliner- TLX(sup TM) system has the unique feature of providing the current line of the statement in execution during real-time execution of the software. The feature of execution line number internal reporting unlocks the capability of monitoring the execution autonomously by use of a companion Timeliner-TLX(sup TM) sequence as the line number reporting is embedded inside the Timeliner-TLX(sup TM) execution engine. This negates I/O processing of this type data as the line number status of executing sequences is built-in as a function reference. This paper will outline the design and capabilities of the AFTS Autonomous Requirements Tracker, which traces and logs SRS requirements as they are being met during real-time execution of the

  20. Real time cardiac radionuclide imaging

    SciTech Connect

    Jarkewicz, G.G.

    1986-04-29

    A data acquisition system is described for use in radionuclide cardiac imaging of a patient having been administered a myocardium specific radionuclide, comprising: (a) means for monitoring the electrical activity of the heart; (b) first temporary storage means for accumulating respective pages of data corresponding to nuclear events during each cardiac cycle; (c) means, responsive to the means for monitoring, for determining the time duration of each successive cardiac cycle; (d) means for comparing each determined duration of a cardiac cycle with a preselected time duration range; (e) second temporary storage means; and (f) means for conditionally transferring pages of data from the first temporary storage means to the second temporary storage means if the measured duration associated with each page has predetermined correspondence with the preselected duration range, whereby pages of data having the predetermined correspondence may be collated into a quasi-real time study, while pages of data having different correspondence with the preselected time duration range are discarded from the study.

  1. Radiation boundary conditions for the numerical solution of the three-dimensional time-dependent Schroedinger equation with a localized interaction

    SciTech Connect

    Heinen, M.; Kull, H.-J.

    2009-05-15

    Exact radiation boundary conditions on the surface of a sphere are presented for the single-particle time-dependent Schroedinger equation with a localized interaction. With these boundary conditions, numerical computations of spatially unbounded outgoing wave solutions can be restricted to the finite volume of a sphere. The boundary conditions are expressed in terms of the free-particle Green's function for the outside region. The Green's function is analytically calculated by an expansion in spherical harmonics and by the method of Laplace transformation. For each harmonic number a discrete boundary condition between the function values at adjacent radial grid points is obtained. The numerical method is applied to quantum tunneling through a spherically symmetric potential barrier with different angular-momentum quantum numbers l. Calculations for l=0 are compared to exact theoretical results.

  2. Receptivity of a laminar boundary layer to the interaction of a three-dimensional roughness element with time-harmonic free-stream disturbances

    NASA Technical Reports Server (NTRS)

    Tadjfar, M.; Bodonyi, R. J.

    1992-01-01

    Receptivity of a laminar boundary layer to the interaction of time-harmonic free-stream disturbances with a 3D roughness element is studied. The 3D nonlinear triple-deck equations are solved numerically to provide the basic steady-state motion. At high Reynolds numbers, the governing equations for the unsteady motion are the unsteady linearized 3D triple-deck equations. These equations can only be solved numerically. In the absence of any roughness element, the free-stream disturbances, to the first order, produce the classical Stokes flow, in the thin Stokes layer near the wall (on the order of our lower deck). However, with the introduction of a small 3D roughness element, the interaction between the hump and the Stokes flow introduces a spectrum of all spatial disturbances inside the boundary layer.

  3. Parallel computation of unsteady, three-dimensional, chemically reacting, nonequilibrium flow using a time-split finite-volume method on the Illiac IV

    NASA Technical Reports Server (NTRS)

    Reinhardt, W. A.

    1977-01-01

    A description is presented of the split finite-volume method which is a viable numerical procedure for performing with the aid of a modern special purpose vector computer numerical simulation studies of complicated flow fields, including chemical reactions, about geometrically complex bodies. Such numerical studies are needed for the development of atmospheric entry vehicles such as the space shuttle. The equations which are approximated are quite general and can be used in studies of combustion, pollution, and other chemically reacting flow phenomena, where convective transport effects dominate the influence of radiative, viscous, and other transport mechanisms. The shock perturbed flow about a shuttle orbiter flying at a large angle of attack during atmospheric entry is illustrated. The method uses a time splitting of the convection differencing operator to achieve efficient data management.

  4. Three-dimensional hologram display system

    NASA Technical Reports Server (NTRS)

    Mintz, Frederick (Inventor); Chao, Tien-Hsin (Inventor); Bryant, Nevin (Inventor); Tsou, Peter (Inventor)

    2009-01-01

    The present invention relates to a three-dimensional (3D) hologram display system. The 3D hologram display system includes a projector device for projecting an image upon a display medium to form a 3D hologram. The 3D hologram is formed such that a viewer can view the holographic image from multiple angles up to 360 degrees. Multiple display media are described, namely a spinning diffusive screen, a circular diffuser screen, and an aerogel. The spinning diffusive screen utilizes spatial light modulators to control the image such that the 3D image is displayed on the rotating screen in a time-multiplexing manner. The circular diffuser screen includes multiple, simultaneously-operated projectors to project the image onto the circular diffuser screen from a plurality of locations, thereby forming the 3D image. The aerogel can use the projection device described as applicable to either the spinning diffusive screen or the circular diffuser screen.

  5. Three dimensional thrust chamber life prediction

    NASA Technical Reports Server (NTRS)

    Armstrong, W. H.; Brogren, E. W.

    1976-01-01

    A study was performed to analytically determine the cyclic thermomechanical behavior and fatigue life of three configurations of a Plug Nozzle Thrust Chamber. This thrust chamber is a test model which represents the current trend in nozzle design calling for high performance coupled with weight and volume limitations as well as extended life for reusability. The study involved the use of different materials and material combinations to evaluate their application to the problem of low-cycle fatigue in the thrust chamber. The thermal and structural analyses were carried out on a three-dimensional basis. Results are presented which show plots of continuous temperature histories and temperature distributions at selected times during the operating cycle of the thrust chamber. Computed structural data show critical regions for low-cycle fatigue and the histories of strain within the regions for each operation cycle.

  6. A 2A2<--X 2B1 absorption and Raman spectra of the OClO molecule: A three-dimensional time-dependent wave packet study

    NASA Astrophysics Data System (ADS)

    Sun, Zhigang; Lou, Nanquan; Nyman, Gunnar

    2005-02-01

    Time-dependent wave packet calculations of the (A 2A2←X 2B1) absorption and Raman spectra of the OClO molecule are reported. The Fourier grid Hamiltonian method in three dimensions is employed. The X 2B1 ground state ab initio potential energy surface reported by Peterson [J. Chem. Phys. 109, 8864 (1998)] is used together with his corresponding A 2A2 state surface or the revised surface of the A 2A2 state by Xie and Guo [Chem. Phys. Lett. 307, 109 (1999)]. Radau coordinates are used to describe the vibrations of a nonrotating OClO molecule. The split-operator method combined with fast Fourier transform is applied to propagate the wave function. We find that the ab initio A 2A2 potential energy surface better reproduces the detailed structures of the absorption spectrum at long wavelength, while the revised surface of the A 2A2 state, consistent with the work of Xie and Guo, better reproduces the overall shape and the energies of the vibrational levels. Both surfaces of the A 2A2 state can reasonably reproduce the experimental Raman spectra but neither does so in detail for the numerical model employed in the present work.

  7. Three-Dimensional Image of Cleavage Bodies in Nuclei Is Configured Using Gas Cluster Ion Beam with Time-of-Flight Secondary Ion Mass Spectrometry

    PubMed Central

    Masaki, Noritaka; Ishizaki, Itsuko; Hayasaka, Takahiro; Fisher, Gregory L.; Sanada, Noriaki; Yokota, Hideo; Setou, Mitsutoshi

    2015-01-01

    Structural variations of DNA in nuclei are deeply related with development, aging, and diseases through transcriptional regulation. In order to bare cross sections of samples maintaining sub-micron structures, an Ar2500+-gas cluster ion beam (GCIB) sputter was recently engineered. By introducing GCIB sputter to time-of-flight secondary ion mass spectrometry (TOF-SIMS), we analyzed the 3D configuration and chemical composition of subnuclear structures of pyramidal cells in the CA2 region in mouse brain hippocampus. Depth profiles of chemicals were analyzed as 3D distributions by combining topographic analyses. Signals corresponding to anions such as CN− and PO3− were distributed characteristically in the shape of cell organelles. CN− signals overlapped DAPI fluorescence signals corresponding to nuclei. The clusters shown by PO3− and those of adenine ions were colocalized inside nuclei revealed by the 3D reconstruction. Taking into account their size and their number in each nucleus, those clusters could be in the cleavage bodies, which are a kind of intranuclear structure. PMID:25961407

  8. A Space-Time Conservation Element and Solution Element Method for Solving the Two- and Three-Dimensional Unsteady Euler Equations Using Quadrilateral and Hexahedral Meshes

    NASA Technical Reports Server (NTRS)

    Zhang, Zeng-Chan; Yu, S. T. John; Chang, Sin-Chung; Jorgenson, Philip (Technical Monitor)

    2001-01-01

    In this paper, we report a version of the Space-Time Conservation Element and Solution Element (CE/SE) Method in which the 2D and 3D unsteady Euler equations are simulated using structured or unstructured quadrilateral and hexahedral meshes, respectively. In the present method, mesh values of flow variables and their spatial derivatives are treated as independent unknowns to be solved for. At each mesh point, the value of a flow variable is obtained by imposing a flux conservation condition. On the other hand, the spatial derivatives are evaluated using a finite-difference/weighted-average procedure. Note that the present extension retains many key advantages of the original CE/SE method which uses triangular and tetrahedral meshes, respectively, for its 2D and 3D applications. These advantages include efficient parallel computing ease of implementing non-reflecting boundary conditions, high-fidelity resolution of shocks and waves, and a genuinely multidimensional formulation without using a dimensional-splitting approach. In particular, because Riemann solvers, the cornerstones of the Godunov-type upwind schemes, are not needed to capture shocks, the computational logic of the present method is considerably simpler. To demonstrate the capability of the present method, numerical results are presented for several benchmark problems including oblique shock reflection, supersonic flow over a wedge, and a 3D detonation flow.

  9. Three-Dimensional Image of Cleavage Bodies in Nuclei Is Configured Using Gas Cluster Ion Beam with Time-of-Flight Secondary Ion Mass Spectrometry.

    PubMed

    Masaki, Noritaka; Ishizaki, Itsuko; Hayasaka, Takahiro; Fisher, Gregory L; Sanada, Noriaki; Yokota, Hideo; Setou, Mitsutoshi

    2015-05-11

    Structural variations of DNA in nuclei are deeply related with development, aging, and diseases through transcriptional regulation. In order to bare cross sections of samples maintaining sub-micron structures, an Ar2500(+)-gas cluster ion beam (GCIB) sputter was recently engineered. By introducing GCIB sputter to time-of-flight secondary ion mass spectrometry (TOF-SIMS), we analyzed the 3D configuration and chemical composition of subnuclear structures of pyramidal cells in the CA2 region in mouse brain hippocampus. Depth profiles of chemicals were analyzed as 3D distributions by combining topographic analyses. Signals corresponding to anions such as CN(-) and PO3(-) were distributed characteristically in the shape of cell organelles. CN(-) signals overlapped DAPI fluorescence signals corresponding to nuclei. The clusters shown by PO3(-) and those of adenine ions were colocalized inside nuclei revealed by the 3D reconstruction. Taking into account their size and their number in each nucleus, those clusters could be in the cleavage bodies, which are a kind of intranuclear structure.

  10. Ordered three-dimensional interconnected nanoarchitectures in anodic porous alumina

    PubMed Central

    Martín, Jaime; Martín-González, Marisol; Fernández, Jose Francisco; Caballero-Calero, Olga

    2014-01-01

    Three-dimensional nanostructures combine properties of nanoscale materials with the advantages of being macro-sized pieces when the time comes to manipulate, measure their properties, or make a device. However, the amount of compounds with the ability to self-organize in ordered three-dimensional nanostructures is limited. Therefore, template-based fabrication strategies become the key approach towards three-dimensional nanostructures. Here we report the simple fabrication of a template based on anodic aluminum oxide, having a well-defined, ordered, tunable, homogeneous 3D nanotubular network in the sub 100 nm range. The three-dimensional templates are then employed to achieve three-dimensional, ordered nanowire-networks in Bi2Te3 and polystyrene. Lastly, we demonstrate the photonic crystal behavior of both the template and the polystyrene three-dimensional nanostructure. Our approach may establish the foundations for future high-throughput, cheap, photonic materials and devices made of simple commodity plastics, metals, and semiconductors. PMID:25342247

  11. Automatic three-dimensional registration of intra-vascular optical coherence tomography images for the clinical evaluation of stent implantation over time

    NASA Astrophysics Data System (ADS)

    Ughi, Giovanni J.; Adriaenssens, Tom; Larsson, Matilda; Dubois, Christophe; Sinnaeve, Peter; Coosemans, Mark; Desmet, Walter; D'hooghe, Jan

    2012-01-01

    In the last decade a large number of new intracoronary devices (i.e. drug-eluting stents, DES) have been developed to reduce the risks related to bare metal stent (BMS) implantation. The use of this new generation of DES has been shown to substantially reduce, compared with BMS, the occurrence of restenosis and recurrent ischemia that would necessitate a second revascularization procedure. Nevertheless, safety issues on the use of DES persist and full understanding of mechanisms of adverse clinical events is still a matter of concern and debate. Intravascular Optical Coherence Tomography (IV-OCT) is an imaging technique able to visualize the microstructure of blood vessels with an axial resolution <20 μm. Due to its very high spatial resolution, it enables detailed in-vivo assessment of implanted devices and vessel wall. Currently, the aim of several major clinical trials is to observe and quantify the vessel response to DES implantation over time. However, image analysis is currently performed manually and corresponding images, belonging to different IV-OCT acquisitions, can only be matched through a very labor intensive and subjective procedure. The aim of this study is to develop and validate a new methodology for the automatic registration of IV-OCT datasets on an image level. Hereto, we propose a landmark based rigid registration method exploiting the metallic stent framework as a feature. Such a tool would provide a better understanding of the behavior of different intracoronary devices in-vivo, giving unique insights about vessel pathophysiology and performance of new generation of intracoronary devices and different drugs.

  12. Real-time automatic registration in optical surgical navigation

    NASA Astrophysics Data System (ADS)

    Lin, Qinyong; Yang, Rongqian; Cai, Ken; Si, Xuan; Chen, Xiuwen; Wu, Xiaoming

    2016-05-01

    An image-guided surgical navigation system requires the improvement of the patient-to-image registration time to enhance the convenience of the registration procedure. A critical step in achieving this aim is performing a fully automatic patient-to-image registration. This study reports on a design of custom fiducial markers and the performance of a real-time automatic patient-to-image registration method using these markers on the basis of an optical tracking system for rigid anatomy. The custom fiducial markers are designed to be automatically localized in both patient and image spaces. An automatic localization method is performed by registering a point cloud sampled from the three dimensional (3D) pedestal model surface of a fiducial marker to each pedestal of fiducial markers searched in image space. A head phantom is constructed to estimate the performance of the real-time automatic registration method under four fiducial configurations. The head phantom experimental results demonstrate that the real-time automatic registration method is more convenient, rapid, and accurate than the manual method. The time required for each registration is approximately 0.1 s. The automatic localization method precisely localizes the fiducial markers in image space. The averaged target registration error for the four configurations is approximately 0.7 mm. The automatic registration performance is independent of the positions relative to the tracking system and the movement of the patient during the operation.

  13. Three-dimensional interactive graphics for displaying and modelling microscopic data.

    PubMed

    Basinski, M; Deatherage, J F

    1990-09-01

    EUCLID is a three-dimensional (3D) general purpose graphics display package for interactive manipulation of vector, surface and solid drawings on Evans and Sutherland PS300 series graphics processors. It is useful for displaying, comparing, measuring and modelling 3D microscopic images in real time. EUCLID can assemble groups of drawings into a composite drawing, while retaining the ability to operate upon the individual drawings within the composite drawing separately. EUCLID is capable of real time geometrical transformations (scaling, translation and rotation in two coordinate frames) and stereo and perspective viewing transformations. Because of its flexibility, EUCLID is especially useful for fitting models into 3D microscopic images.

  14. Advanced Three-Dimensional Display System

    NASA Technical Reports Server (NTRS)

    Geng, Jason

    2005-01-01

    A desktop-scale, computer-controlled display system, initially developed for NASA and now known as the VolumeViewer(TradeMark), generates three-dimensional (3D) images of 3D objects in a display volume. This system differs fundamentally from stereoscopic and holographic display systems: The images generated by this system are truly 3D in that they can be viewed from almost any angle, without the aid of special eyeglasses. It is possible to walk around the system while gazing at its display volume to see a displayed object from a changing perspective, and multiple observers standing at different positions around the display can view the object simultaneously from their individual perspectives, as though the displayed object were a real 3D object. At the time of writing this article, only partial information on the design and principle of operation of the system was available. It is known that the system includes a high-speed, silicon-backplane, ferroelectric-liquid-crystal spatial light modulator (SLM), multiple high-power lasers for projecting images in multiple colors, a rotating helix that serves as a moving screen for displaying voxels [volume cells or volume elements, in analogy to pixels (picture cells or picture elements) in two-dimensional (2D) images], and a host computer. The rotating helix and its motor drive are the only moving parts. Under control by the host computer, a stream of 2D image patterns is generated on the SLM and projected through optics onto the surface of the rotating helix. The system utilizes a parallel pixel/voxel-addressing scheme: All the pixels of the 2D pattern on the SLM are addressed simultaneously by laser beams. This parallel addressing scheme overcomes the difficulty of achieving both high resolution and a high frame rate in a raster scanning or serial addressing scheme. It has been reported that the structure of the system is simple and easy to build, that the optical design and alignment are not difficult, and that the

  15. Three-dimensional vortex structures in a rotating dipolar Bose–Einstein condensate

    NASA Astrophysics Data System (ADS)

    Kishor Kumar, Ramavarmaraja; Sriraman, Thangarasu; Fabrelli, Henrique; Muruganandam, Paulsamy; Gammal, Arnaldo

    2016-08-01

    We study three-dimensional vortex lattice structures in purely dipolar Bose–Einstein condensate (BEC). By using the mean-field approximation, we obtain a stability diagram for the vortex states in purely dipolar BECs as a function of harmonic trap aspect ratio (λ) and dipole–dipole interaction strength (D) under rotation. Rotating the condensate within the unstable region leads to collapse while in the stable region furnishes stable vortex lattices of dipolar BECs. We analyse stable vortex lattice structures by solving the three-dimensional time-dependent Gross–Pitaevskii equation in imaginary time. Further, the stability of vortex states is examined by evolution in real-time. We also investigate the distribution of vortices in a fully anisotropic trap by increasing eccentricity of the external trapping potential. We observe the breaking up of the condensate in two parts with an equal number of vortices on each when the trap is sufficiently weak, and the rotation frequency is high.

  16. Real-time data standards for the planetarium

    NASA Astrophysics Data System (ADS)

    Abbott, B.

    2008-06-01

    The American Museum of Natural History and the Hayden Planetarium have built the most accurate, comprehensive, 3-D atlas of the cosmos called the Digital Universe (DU). The DU enables one to journey from the mountains on Earth to the farthest quasars. The DU enjoys many distribution channels, including pre-rendered space-shows and news bulletins, live planetarium programmes, and a free version available on the internet. Recently, we have partnered with three planetarium vendors to bring the DU to planetariums around the world. These partnerships necessitatethe adoption or creation of standards for three-dimensional data and associated metadata. Many standards exist in the current Virtual Observatory framework and additional standards are being proposed as part of the VAMP programme. We intend to identify additional standards necessary for 3-D, real-time rendering tools for fulldome and flat-screen environments.

  17. Design considerations for a real-time ocular counterroll instrument

    NASA Technical Reports Server (NTRS)

    Hatamian, M.; Anderson, D. J.

    1983-01-01

    A real-time algorithm for measuring three-dimensional movement of the human eye, especially torsional movement, is presented. As its input, the system uses images of the eyeball taken at video rate. The amount of horizontal and vertical movement is extracted using a pupil tracking technique. The torsional movement is then measured by computing the discrete cross-correlation function between the circular samples of successive images of the iris patterns and searching for the position of the peak of the function. A local least square interpolation around the peak of the cross-correlation function is used to produce nearly unbiased estimates of torsion angle with accuracy of about 3-4 arcmin. Accuracies of better than 0.03 deg are achievable in torsional measurement with SNR higher than 36 dB. Horizontal and vertical rotations of up to + or - 13 deg can occur simultaneously with torsion without introducing any appreciable error in the counterrolling measurement process.

  18. Two and three dimensional magnetotelluric inversion

    SciTech Connect

    Booker, J.

    1993-01-01

    Electrical conductivity depends on properties such as the presence of ionic fluids in interconnected pores that are difficult to sense with other remote sensing techniques. Thus improved imaging of underground electrical structure has wide practical importance in exploring for groundwater, mineral and geothermal resources, and in assessing the diffusion of fluids in oil fields and waste sites. Because the electromagnetic inverse problem is fundamentally multi-dimensional, most imaging algorithms saturate available computer power long before they can deal with the complete data set. We have developed an algorithm to directly invert large multi-dimensional data sets that is orders of magnitude faster than competing methods. We have proven that a two-dimensional (2D) version of the algorithm is highly effective for real data and have made substantial progress towards a three-dimensional (3D) version. We are proposing to cure identified shortcomings and substantially expand the utility of the existing 2D program, overcome identified difficulties with extending our method to three-dimensions (3D) and embark on an investigation of related EM imaging techniques which may have the potential for even further increasing resolution.

  19. Three Dimensional Illustrating--Three-Dimensional Vision and Deception of Sensibility

    ERIC Educational Resources Information Center

    Szállassy, Noémi; Gánóczy, Anita; Kriska, György

    2009-01-01

    The wide-spread digital photography and computer use gave the opportunity for everyone to make three-dimensional pictures and to make them public. The new opportunities with three-dimensional techniques give chance for the birth of new artistic photographs. We present in detail the biological roots of three-dimensional visualization, the phenomena…

  20. Real-time scene generator

    NASA Astrophysics Data System (ADS)

    Lord, Eric; Shand, David J.; Cantle, Allan J.

    1996-05-01

    This paper describes the techniques which have been developed for an infra-red (IR) target, countermeasure and background image generation system working in real time for HWIL and Trial Proving applications. Operation is in the 3 to 5 and 8 to 14 micron bands. The system may be used to drive a scene projector (otherwise known as a thermal picture synthesizer) or for direct injection into equipment under test. The provision of realistic IR target and countermeasure trajectories and signatures, within representative backgrounds, enables the full performance envelope of a missile system to be evaluated. It also enables an operational weapon system to be proven in a trials environment without compromising safety. The most significant technique developed has been that of line by line synthesis. This minimizes the processing delays to the equivalent of 1.5 frames from input of target and sightline positions to the completion of an output image scan. Using this technique a scene generator has been produced for full closed loop HWIL performance analysis for the development of an air to air missile system. Performance of the synthesis system is as follows: 256 * 256 pixels per frame; 350 target polygons per frame; 100 Hz frame rate; and Gouraud shading, simple reflections, variable geometry targets and atmospheric scaling. A system using a similar technique has also bee used for direct insertion into the video path of a ground to air weapon system in live firing trials. This has provided realistic targets without degrading the closed loop performance. Delay of the modified video signal has been kept to less than 5 lines. The technique has been developed using a combination of 4 high speed Intel i860 RISC processors in parallel with the 4000 series XILINX field programmable gate arrays (FPGA). Start and end conditions for each line of target pixels are prepared and ordered in the I860. The merging with background pixels and output shading and scaling is then carried out in

  1. Real-Time Data Display

    NASA Technical Reports Server (NTRS)

    Pedings, Marc

    2007-01-01

    RT-Display is a MATLAB-based data acquisition environment designed to use a variety of commercial off-the-shelf (COTS) hardware to digitize analog signals to a standard data format usable by other post-acquisition data analysis tools. This software presents the acquired data in real time using a variety of signal-processing algorithms. The acquired data is stored in a standard Operator Interactive Signal Processing Software (OISPS) data-formatted file. RT-Display is primarily configured to use the Agilent VXI (or equivalent) data acquisition boards used in such systems as MIDDAS (Multi-channel Integrated Dynamic Data Acquisition System). The software is generalized and deployable in almost any testing environment, without limitations or proprietary configuration for a specific test program or project. With the Agilent hardware configured and in place, users can start the program and, in one step, immediately begin digitizing multiple channels of data. Once the acquisition is completed, data is converted into a common binary format that also can be translated to specific formats used by external analysis software, such as OISPS and PC-Signal (product of AI Signal Research Inc.). RT-Display at the time of this reporting was certified on Agilent hardware capable of acquisition up to 196,608 samples per second. Data signals are presented to the user on-screen simultaneously for 16 channels. Each channel can be viewed individually, with a maximum capability of 160 signal channels (depending on hardware configuration). Current signal presentations include: time data, fast Fourier transforms (FFT), and power spectral density plots (PSD). Additional processing algorithms can be easily incorporated into this environment.

  2. Mobile real time radiography system

    SciTech Connect

    Vigil, J.; Taggart, D.; Betts, S.

    1997-11-01

    A 450-keV Mobile Real Time Radiography (RTR) System was delivered to Los Alamos National Laboratory (LANL) in January 1996. It was purchased to inspect containers of radioactive waste produced at (LANL). Since its delivery it has been used to radiograph more than 600 drums of radioactive waste at various LANL sites. It has the capability of inspecting waste containers of various sizes from <1-gal. buckets up to standard waste boxes (SWB, dimensions 54.5 in. x 71 in. x 37 in.). It has three independent x-ray acquisition formats. The primary system used is a 12- in. image intensifier, the second is a 36-in. linear diode array (LDA) and the last is an open system. It is fully self contained with on board generator, HVAC, and a fire suppression system. It is on a 53-ft long x 8-ft. wide x 14-ft. high trailer that can be moved over any highway requiring only an easily obtainable overweight permit because it weights {approximately}38 tons. It was built to conform to industry standards for a cabinet system which does not require an exclusion zone. The fact that this unit is mobile has allowed us to operate where the waste is stored, rather than having to move the waste to a fixed facility.

  3. Three-dimensional laser window formation

    NASA Technical Reports Server (NTRS)

    Verhoff, Vincent G.

    1992-01-01

    The NASA Lewis Research Center has developed and implemented a unique process for forming flawless three-dimensional laser windows. These windows represent a major part of specialized, nonintrusive laser data acquisition systems used in a variety of compressor and turbine research test facilities. This report discusses in detail the aspects of three-dimensional laser window formation. It focuses on the unique methodology and the peculiarities associated with the formation of these windows. Included in this discussion are the design criteria, bonding mediums, and evaluation testing for three-dimensional laser windows.

  4. Three Dimensional Probability Distributions of the Interplanetary Magnetic Field

    NASA Astrophysics Data System (ADS)

    Podesta, J. J.

    2014-12-01

    Empirical probability density functions (PDFs) of the interplanetary magnetic field (IMF) have been derived from spacecraft data since the early years of the space age. A survey of the literature shows that past studies have investigated the separate Cartesian components of the magnetic field, the vector magnitude, and the direction of the IMF by means of one-dimensional or two-dimensional PDFs. But, to my knowledge, there exist no studies which investigate the three dimensional nature of the IMF by means of three dimensional PDFs, either in (Bx,By,Bz)(B_x,B_y,B_z)-coordinates or (BR,BT,BN)(B_R,B_T,B_N)-coordinates or some other appropriate system of coordinates. Likewise, there exist no studies which investigate three dimensional PDFs of magnetic field fluctuations, that is, vector differences bmB(t+τ)-bmB(t)bm{B}(t+tau)-bm{B}(t). In this talk, I shall present examples of three dimensional PDFs obtained from spacecraft data that demonstrate the solar wind magnetic field possesses a very interesting spatial structure that, to my knowledge, has not previously been identified. Perhaps because of the well known model of Barnes (1981) in which the magnitude of the IMF remains constant, it may be commonly believed that there is nothing new to learn from a full three dimensional PDF. To the contrary, there is much to learn from the investigation of three dimensional PDFs of the solar wind plasma velocity and the magnetic field, as well as three dimensional PDFs of their fluctuations. Knowledge of these PDFs will not only improve understanding of solar wind physics, it is an essential prerequisite for the construction of realistic models of the stochastic time series measured by a single spacecraft, one of the longstanding goals of space physics research. In addition, three dimensional PDFs contain valuable information about the anisotropy of solar wind fluctuations in three dimensional physical space, information that may help identify the reason why the three

  5. "Three-dimensional" vibration fixture

    NASA Technical Reports Server (NTRS)

    Schumacher, C. A.

    1980-01-01

    Simple cube-shaped fixture reduces vibration-test time to one-third required previously. Three units are supported at once. During one run each unit is tested along one of axes. Units are repositioned on second run for tests along different axes. Three runs complete test; fixture can be set up to test small, lightweight high-production units.

  6. Three Dimensional Optic Tissue Culture and Process

    NASA Technical Reports Server (NTRS)

    OConnor, Kim C. (Inventor); Spaulding, Glenn F. (Inventor); Goodwin, Thomas J. (Inventor); Aten, Laurie A. (Inventor); Francis, Karen M. (Inventor); Caldwell, Delmar R. (Inventor); Prewett, Tacey L. (Inventor); Fitzgerald, Wendy S. (Inventor)

    1999-01-01

    A process for artificially producing three-dimensional optic tissue has been developed. The optic cells are cultured in a bioireactor at low shear conditions. The tissue forms as normal, functional tissue grows with tissue organization and extracellular matrix formation.

  7. Three dimensional optic tissue culture and process

    NASA Technical Reports Server (NTRS)

    Spaulding, Glenn F. (Inventor); Prewett, Tacey L. (Inventor); Goodwin, Thomas J. (Inventor); Francis, Karen M. (Inventor); Cardwell, Delmar R. (Inventor); Oconnor, Kim (Inventor); Fitzgerald, Wendy S. (Inventor); Aten, Laurie A. (Inventor)

    1994-01-01

    A process for artificially producing three-dimensional optic tissue has been developed. The optic cells are cultured in a bioreactor at low shear conditions. The tissue forms normal, functional tissue organization and extracellular matrix.

  8. Three Dimensional Primary Hepatocyte Culture

    NASA Technical Reports Server (NTRS)

    Yoffe, Boris

    1998-01-01

    Our results demonstrated for the first time the feasibility of culturing PHH in microgravity bioreactors that exceeded the longest period obtained using other methods. Within the first week of culture, isolated hepatocytes started to form aggregates, which continuously increased in size (up to 1 cm) and macroscopically appeared as a multidimensional tissue-like assembly. To improve oxygenation and nutrition within the spheroids we performed experiments with the biodegradable nonwoven fiber-based polymers made from PolyGlycolic Acid (PGA). It has been shown that PGA scaffolds stimulate isolated cells to regenerate tissue with defined sizes and shapes and are currently being studied for various tissue-engineering applications. Our data demonstrated that culturing hepatocytes in the presence of PGA scaffolds resulted in more efficient cell assembly and formations of larger cell spheroids (up to 3 cm in length, see figure). The histology of cell aggregates cultured with PGA showed polymer fibers with attached hepatocytes. We initiated experiments to co-culture primary human hepatocytes with human microvascular endothelial cells in the bioreactor. The presence of endothelial cells in co-cultures were established by immunohistochemistry using anti-CD34 monoclonal Ab. Our preliminary data demonstrated that cultures of purified hepatocytes with human microvascular endothelial cells exhibited better growth and expressed higher levels of albumin MRNA for a longer period of time than cultures of ppfified, primary human hepatocytes cultured alone. We also evaluated microsomal deethylation activity of hepatocytes cultured in the presence of endothelial cells.In summary, we have established liver cell culture, which mimicked the structure and function of the parent tissue.

  9. Students Collecting Real time Data

    NASA Astrophysics Data System (ADS)

    Miller, P.

    2006-05-01

    Students Collecting Real-Time Data The Hawaiian Islands Humpback Whale National Marine Sanctuary has created opportunities for middle and high school students to become Student Researchers and to be involved in real-time marine data collection. It is important that we expose students to different fields of science and encourage them to enter scientific fields of study. The Humpback Whale Sanctuary has an education visitor center in Kihei, Maui. Located right on the beach, the site has become a living classroom facility. There is a traditional Hawaiian fishpond fronting the property. The fishpond wall is being restored, using traditional methods. The site has the incredible opportunity of incorporating Hawaiian cultural practices with scientific studies. The Sanctuary offers opportunities for students to get involved in monitoring and data collection studies. Invasive Seaweed Study: Students are collecting data on invasive seaweed for the University of Hawaii. They pull a large net through the shallow waters. Seaweed is sorted, identified and weighed. The invasive seaweeds are removed. The data is recorded and sent to UH. Remote controlled monitoring boats: The sanctuary has 6 boogie board sized remote controlled boats used to monitor reefs. Boats have a camera with lights on the underside. The boats have water quality monitoring devices and GPS units. The video from the underwater camera is transmitted via a wireless transmission. Students are able to monitor the fish, limu and invertebrate populations on the reef and collect water quality data via television monitors or computers. The boat can also pull a small plankton tow net. Data is being compiled into data bases. Artificial Reef Modules: The Sanctuary has a scientific permit from the state to build and deploy artificial reef modules. High school students are designing and building modules. These are deployed out in the Fishpond fronting the Sanctuary site and students are monitoring them on a weekly basis

  10. Three-Dimensional Icosahedral Phase Field Quasicrystal

    NASA Astrophysics Data System (ADS)

    Subramanian, P.; Archer, A. J.; Knobloch, E.; Rucklidge, A. M.

    2016-08-01

    We investigate the formation and stability of icosahedral quasicrystalline structures using a dynamic phase field crystal model. Nonlinear interactions between density waves at two length scales stabilize three-dimensional quasicrystals. We determine the phase diagram and parameter values required for the quasicrystal to be the global minimum free energy state. We demonstrate that traits that promote the formation of two-dimensional quasicrystals are extant in three dimensions, and highlight the characteristics required for three-dimensional soft matter quasicrystal formation.

  11. Large holographic displays for real-time applications

    NASA Astrophysics Data System (ADS)

    Schwerdtner, A.; Häussler, R.; Leister, N.

    2008-02-01

    Holography is generally accepted as the ultimate approach to display three-dimensional scenes or objects. Principally, the reconstruction of an object from a perfect hologram would appear indistinguishable from viewing the corresponding real-world object. Up to now two main obstacles have prevented large-screen Computer-Generated Holograms (CGH) from achieving a satisfactory laboratory prototype not to mention a marketable one. The reason is a small cell pitch CGH resulting in a huge number of hologram cells and a very high computational load for encoding the CGH. These seemingly inevitable technological hurdles for a long time have not been cleared limiting the use of holography to special applications, such as optical filtering, interference, beam forming, digital holography for capturing the 3-D shape of objects, and others. SeeReal Technologies has developed a new approach for real-time capable CGH using the socalled Tracked Viewing Windows technology to overcome these problems. The paper will show that today's state of the art reconfigurable Spatial Light Modulators (SLM), especially today's feasible LCD panels are suited for reconstructing large 3-D scenes which can be observed from large viewing angles. For this to achieve the original holographic concept of containing information from the entire scene in each part of the CGH has been abandoned. This substantially reduces the hologram resolution and thus the computational load by several orders of magnitude making thus real-time computation possible. A monochrome real-time prototype measuring 20 inches has been built and demonstrated at last year's SID conference and exhibition 2007 and at several other events.

  12. Real time UAV autonomy through offline calculations

    NASA Astrophysics Data System (ADS)

    Jung, Sunghun

    Two or three dimensional mission plans for a single or a group of hover or fixed wing UAVs are generated. The mission plans can largely be separated into seven main parts. Firstly, the Region Growing algorithm is used to generate a map from 2D or 3D images. Secondly, the map is analyzed to separate each blocks using vertices of blocks and seven filtering steps. Thirdly, the Trapezoidal map algorithm is used to convert the map into a traversability graph. Fourthly, this process also filters out paths that are not traversable. That is, nodes located inside the blocks and too closely located nodes are filtered out. Fifthly, the Dijkstra algorithm is used to calculate the shortest path from a starting point to a goal point. Sixthly, the 1D Optimal Control algorithm is applied to manipulate the velocity and acceleration of the UAVs efficiently. Basically, the UAVs accelerates at one graph node and maintains a constant velocity and decelerates before reaching the next graph node. Lastly, Traveling Salesman Problem Method (TSP) algorithm is used to calculate the shortest path to search the whole region. After this discretization of space and time, it becomes possible to solve several autonomous mission planning problems. We focus on one of the most difficult problems: coordinated search. This is a multiple Traveling Salesman Problem (mTSP). We solve it by decomposing the search region and solving TSPs for each vehicle searching a sub-region. The mTSP is generally used when there are more than one salesman is used. In addition to the four main parts, there are three minor parts which support the main parts. Firstly, Target Detection algorithm is generated to detect a target located near the UAVs' path. A picture of the desired target is inserted into the algorithm before UAVs launch. Using the Scale-Invariant Transform Feature (SIFT) algorithm, a target with a specific shape can be detected. Secondly, Tracking algorithm is generated to manipulate UAVs to follow targets

  13. Networked virtual reality for real-time 4D navigation of astrophysical turbulence data

    SciTech Connect

    Hudson, R.; Malagoli, A.

    1996-11-01

    This paper describes a prototype distributed virtual reality system for real-time spatial and temporal navigation of volumetric data generated by simulations of hydrodynamic turbulence on high-performance computers. This system makes use of a virtual environment connected to a scalably parallel computer via a scalably high-speed network. The data are either computed in real-time or precomputed on the parallel computer, then are transferred to the virtual environment where fast volume visualization is accomplished by using sophisticated three-dimensional texture-mapping hardware.

  14. FT3D: three-dimensional Fourier analysis on small Unix workstations for electron microscopy and tomographic studies.

    PubMed

    Lanzavecchia, S; Bellon, P L; Tosoni, L

    1993-12-01

    FT3D is a self-contained package of tools for three-dimensional Fourier analysis, written in the C language for Unix workstations. It can evaluate direct transforms of three-dimensional real functions, inverse transforms, auto- and cross-correlations and spectra. The library has been developed to support three-dimensional reconstructions of biological structures from projections obtained in the electron microscope. This paper discusses some features of the library, which has been implemented in such a way as to profit from the resources of modern workstations. A table of elapsed times for jobs of different dimensions with different RAM buffers is reported for the particular hardware used in the authors' laboratory.

  15. Three-dimensional modeling of tsunami waves

    SciTech Connect

    Mader, C.L.

    1985-01-01

    Two- and three-dimensional, time-dependent, nonlinear, incompressible, viscous flow calculations of realistic models of tsunami wave formation and run up have been performed using the Los Alamos-developed SOLA-3D code. The results of the SOLA calculations are compared with shallow-water, long-wave calculations for the same problems using the SWAN code. Tsunami wave formation by a continental slope subsidence has been examined using the two numerical models. The SOLA waves were slower than the SWAN waves and the interaction with the shoreline was more complicated for the SOLA waves. In the SOLA calculation, the first wave was generated by the cavity being filled along the shoreline close to the source of motion. The second wave was generated by the cavity being filled from the deep water end. The two waves interacted along the shoreline resulting in the second wave being the largest wave with a velocity greater than the first wave. The second wave overtook the first wave at later times and greater distances from the source. In the SWAN calculation, the second wave was smaller than the first wave. 6 refs.

  16. Three-Dimensional Super-Resolution: Theory, Modeling, and Field Tests Results

    NASA Technical Reports Server (NTRS)

    Bulyshev, Alexander; Amzajerdian, Farzin; Roback, Vincent E.; Hines, Glenn; Pierrottet, Diego; Reisse, Robert

    2014-01-01

    Many flash lidar applications continue to demand higher three-dimensional image resolution beyond the current state-of-the-art technology of the detector arrays and their associated readout circuits. Even with the available number of focal plane pixels, the required number of photons for illuminating all the pixels may impose impractical requirements on the laser pulse energy or the receiver aperture size. Therefore, image resolution enhancement by means of a super-resolution algorithm in near real time presents a very attractive solution for a wide range of flash lidar applications. This paper describes a superresolution technique and illustrates its performance and merits for generating three-dimensional image frames at a video rate.

  17. Formation of a topological monopole lattice and its dynamics in three-dimensional chiral magnets

    NASA Astrophysics Data System (ADS)

    Yang, Seong-Gyu; Liu, Ye-Hua; Han, Jung Hoon

    2016-08-01

    Topologically protected swirl of the magnetic texture known as the skyrmion has become ubiquitous in both metallic and insulating chiral magnets. Meanwhile the existence of its three-dimensional analog, known as the magnetic monopole, has been suggested by various indirect experimental signatures in MnGe compound. Although Ginzburg-Landau arguments in favor of the formation of a three-dimensional crystal of monopoles and antimonopoles have been put forward, no microscopic model Hamiltonian was shown to support such a phase. Here we present strong numerical evidence from Monte Carlo simulations for the formation of a rocksalt crystal structure of monopoles and antimonopoles in short-period chiral magnets. Real-time simulation of the spin dynamics suggests there is only one internal excitation mode in the monopole crystal state in the frequency range of several gigahertz for the material parameters of MnGe.

  18. Three-dimensional models. [For orbital celestial mechanics

    SciTech Connect

    Hunter, C. )

    1990-06-01

    The Schwarzschild (1979) approach to the analysis of three-dimensional galactic models is reviewed. An analysis of triaxial Staeckel models is discussed which shows that such models have a wide variety of possible distribution functions. The uniqueness that Schwarzschild first encountered in his discrete formulation of the problem of finding a three-integral distribution function for a triaxial density is real and not an artifact of the finite cell approximation. 27 refs.

  19. Flow Fields Over Unsteady Three Dimensional Dunes

    NASA Astrophysics Data System (ADS)

    Hardy, R. J.; Reesink, A.; Parsons, D. R.; Ashworth, P. J.; Best, J.

    2013-12-01

    The flow field over dunes has been extensively measured in laboratory conditions and there is general understanding on the nature of the flow over dunes formed under equilibrium flow conditions. However, fluvial systems typically experience unsteady flow and therefore the sediment-water interface is constantly responding and reorganizing to these unsteady flows, over a range of both spatial and temporal scales. This is primarily through adjustment of bed forms (including ripples, dunes and bar forms) which then subsequently alter the flow field. This paper investigates, through the application of a numerical model, the influence of these roughness elements on the overall flow and the increase in flow resistance. A series of experiments were undertaken in a flume, 16m long and 2m wide, where a fine sand (D50 of 239μm) mobile bed was water worked under a range of unsteady hydraulic conditions to generate a series of quasi-equilibrium three dimensional bed forms. During the experiments flow was measured with acoustic Doppler velocimeters, (aDv's). On four occasions the flume was drained and the bed topography measured with terrestrial LiDAR to create digital elevation models. This data provide the necessary boundary conditions and validation data for a Large Eddy Simulation (LES) model, which provided a three dimensional time dependent prediction of flow over the four static beds. The numerical predicted flow is analyzed through a series of approaches, and included: i) standard Reynolds decomposition to the flow fields; ii) Eulerian coherent structure detection methods based on the invariants of the velocity gradient tensor; iii) Lagrangian coherent structure identification methods based upon direct Lyapunov exponents (DLE). The results show that superimposed bed forms can cause changes in the nature of the classical separated flow region in particularly the number of locations where vortices are shed and the point of flow reattachment, which may be important for

  20. Three-dimensional, three-component wall-PIV

    NASA Astrophysics Data System (ADS)

    Berthe, André; Kondermann, Daniel; Christensen, Carolyn; Goubergrits, Leonid; Garbe, Christoph; Affeld, Klaus; Kertzscher, Ulrich

    2010-06-01

    This paper describes a new time-resolved three-dimensional, three-component (3D-3C) measurement technique called wall-PIV. It was developed to assess near wall flow fields and shear rates near non-planar surfaces. The method is based on light absorption according to Beer-Lambert’s law. The fluid containing a molecular dye and seeded with buoyant particles is illuminated by a monochromatic, diffuse light. Due to the dye, the depth of view is limited to the near wall layer. The three-dimensional particle positions can be reconstructed by the intensities of the particle’s projection on an image sensor. The flow estimation is performed by a new algorithm, based on learned particle trajectories. Possible sources of measurement errors related to the wall-PIV technique are analyzed. The accuracy analysis was based on single particle experiments and a three-dimensional artificial data set simulating a rotating sphere.

  1. Coupled particle dispersion by three-dimensional vortex structures

    SciTech Connect

    Troutt, T.R.; Chung, J.N.; Crowe, C.T.

    1996-12-31

    The primary objective of this research program is to obtain understanding concerning the role of three-dimensional vortex structures in the dispersion of particles and droplets in free shear flows. This research program builds on previous studies which focused on the nature of particle dispersion in large scale quasi two-dimensional vortex structures. This investigation employs time dependent experimental and numerical techniques to provide information concerning the particulate dispersion produced by three dimensional vortex structures in free shear layers. The free shear flows investigated include modified plane mixing layers, and modified plane wakes. The modifications to these flows involve slight perturbations to the initiation boundary conditions such that three-dimensional vortex structures are rapidly generated by the experimental and numerical flow fields. Recent results support the importance of these vortex structures in the particle dispersion process.

  2. Radiation hardness of three-dimensional polycrystalline diamond detectors

    SciTech Connect

    Lagomarsino, Stefano Sciortino, Silvio; Bellini, Marco; Corsi, Chiara; Cindro, Vladimir; Kanxheri, Keida; Servoli, Leonello; Morozzi, Arianna; Passeri, Daniele; Schmidt, Christian J.

    2015-05-11

    The three-dimensional concept in particle detection is based on the fabrication of columnar electrodes perpendicular to the surface of a solid state radiation sensor. It permits to improve the radiation resistance characteristics of a material by lowering the necessary bias voltage and shortening the charge carrier path inside the material. If applied to a long-recognized exceptionally radiation-hard material like diamond, this concept promises to pave the way to the realization of detectors of unprecedented performances. We fabricated conventional and three-dimensional polycrystalline diamond detectors, and tested them before and after neutron damage up to 1.2 ×10{sup 16 }cm{sup −2}, 1 MeV-equivalent neutron fluence. We found that the signal collected by the three-dimensional detectors is up to three times higher than that of the conventional planar ones, at the highest neutron damage ever experimented.

  3. Visualization of three-dimensional liquid flow on sieve trays

    NASA Astrophysics Data System (ADS)

    Wang, Xiaoling

    2004-03-01

    This paper presents the simulated result of three-dimensional liquid velocity profile on sieve trays by using a computational flow dynamics (CFD) model with considerations of volume fraction of gas and liquid and the interfacial forces. The Κ-ɛ equation is used for the closure of basic equations. For the first time the three-dimensional liquid flow on a distillation column with ten trays under total reflux is visualized. The simulation was carried out with an Origin 200 Server Workstation of SGI Company using Star-CD V3.1 program. Simulation provides the detailed information of the distribution of 3D liquid velocity on the distillation column.

  4. Binary Colloidal Alloy Test-5: Three-Dimensional Melt

    NASA Technical Reports Server (NTRS)

    Yodh, Arjun G.

    2008-01-01

    Binary Colloidal Alloy Test - 5: Three-Dimensional Melt (BCAT-5-3DMelt) photographs initially randomized colloidal samples in microgravity to determine their resulting structure over time. BCAT-5-3D-Melt will allow the scientists to capture the kinetics (evolution) of their samples, as well as the final equilibrium state of each sample. BCAT-5-3D-Melt will look at the mechanisms of melting using three-dimensional temperature sensitive colloidal crystals. Results will help scientists develop fundamental physics concepts previously shadowed by the effects of gravity.

  5. A low cost real-time motion tracking approach using webcam technology.

    PubMed

    Krishnan, Chandramouli; Washabaugh, Edward P; Seetharaman, Yogesh

    2015-02-01

    Physical therapy is an important component of gait recovery for individuals with locomotor dysfunction. There is a growing body of evidence that suggests that incorporating a motor learning task through visual feedback of movement trajectory is a useful approach to facilitate therapeutic outcomes. Visual feedback is typically provided by recording the subject's limb movement patterns using a three-dimensional motion capture system and displaying it in real-time using customized software. However, this approach can seldom be used in the clinic because of the technical expertise required to operate this device and the cost involved in procuring a three-dimensional motion capture system. In this paper, we describe a low cost two-dimensional real-time motion tracking approach using a simple webcam and an image processing algorithm in LabVIEW Vision Assistant. We also evaluated the accuracy of this approach using a high precision robotic device (Lokomat) across various walking speeds. Further, the reliability and feasibility of real-time motion-tracking were evaluated in healthy human participants. The results indicated that the measurements from the webcam tracking approach were reliable and accurate. Experiments on human subjects also showed that participants could utilize the real-time kinematic feedback generated from this device to successfully perform a motor learning task while walking on a treadmill. These findings suggest that the webcam motion tracking approach is a feasible low cost solution to perform real-time movement analysis and training. PMID:25555306

  6. A low cost real-time motion tracking approach using webcam technology.

    PubMed

    Krishnan, Chandramouli; Washabaugh, Edward P; Seetharaman, Yogesh

    2015-02-01

    Physical therapy is an important component of gait recovery for individuals with locomotor dysfunction. There is a growing body of evidence that suggests that incorporating a motor learning task through visual feedback of movement trajectory is a useful approach to facilitate therapeutic outcomes. Visual feedback is typically provided by recording the subject's limb movement patterns using a three-dimensional motion capture system and displaying it in real-time using customized software. However, this approach can seldom be used in the clinic because of the technical expertise required to operate this device and the cost involved in procuring a three-dimensional motion capture system. In this paper, we describe a low cost two-dimensional real-time motion tracking approach using a simple webcam and an image processing algorithm in LabVIEW Vision Assistant. We also evaluated the accuracy of this approach using a high precision robotic device (Lokomat) across various walking speeds. Further, the reliability and feasibility of real-time motion-tracking were evaluated in healthy human participants. The results indicated that the measurements from the webcam tracking approach were reliable and accurate. Experiments on human subjects also showed that participants could utilize the real-time kinematic feedback generated from this device to successfully perform a motor learning task while walking on a treadmill. These findings suggest that the webcam motion tracking approach is a feasible low cost solution to perform real-time movement analysis and training.

  7. An H-formulation-based three-dimensional hysteresis loss modelling tool in a simulation including time varying applied field and transport current: the fundamental problem and its solution

    NASA Astrophysics Data System (ADS)

    Stenvall, A.; Lahtinen, V.; Lyly, M.

    2014-10-01

    When analytic solutions are not available, finite-element-based tools can be used to simulate hysteresis losses in superconductors with various shapes. A widely used tool for the corresponding magnetoquasistatic problem is based on the H-formulation, where H is the magnetic field intensity, eddy current model. In this paper, we study this type of tool in a three-dimensional simulation problem. We consider a case where we simultaneously apply both a time-varying external magnetic field and a transport current to a twisted wire. We show how the modelling decisions (air has high finite resistivity and applied field determines the boundary condition) affect the current density distribution along the wire. According to the results, the wire carries the imposed net current only on the boundary of the modelling domain, but not inside it. The current diffuses to the air and back to the boundary. To fix this problem, we present another formulation where air is treated as a region with 0 conductivity. Correspondingly, we express H in the air with a scalar potential and a cohomology basis function which considers the net current condition. As shown in this paper, this formulation does not fail in these so-called AC-AC (time varying transport current and applied magnetic field) simulations.

  8. Three dimensional simulations of internal solitary waves

    NASA Astrophysics Data System (ADS)

    Li, Guotu; Rizzi, Francesco; Knio, Omar

    2014-11-01

    This study focuses on mass transport and mixing induced by mode-2 internal solitary waves (ISWs) propagating along a pycnocline between two continuously stratified fluid layers. A direct numerical simulation (DNS) model is developed for the incompressible three-dimensional Navier-Stokes equations in the Boussinesq limit. By using high order schemes in both space and time, the model is able to accurately capture the convection-dominated flow at high Reynolds and Schmidt numbers. Simulations both with and without background shear are conducted. The spatial frequency analysis of both density and vorticity fields reveals that no long range spanwise structures are present during the propagation of ISWs, which makes a relatively short spanwise depth sufficient to characterize the evolution of the flow. The growth of 3D structures during the propagation of ISWs is quantified using a spanwise roughness measure. The flow energy budget, dye transport, density mixing and vortex circulations are also analyzed. Work supported by the Office of Naval Research, Physical Oceanography Program.

  9. A three-dimensional human walking model

    NASA Astrophysics Data System (ADS)

    Yang, Q. S.; Qin, J. W.; Law, S. S.

    2015-11-01

    A three-dimensional human bipedal walking model with compliant legs is presented in this paper. The legs are modeled with time-variant dampers, and the model is able to characterize the gait pattern of an individual using a minimal set of parameters. Feedback control, for both the forward and lateral movements, is implemented to regulate the walking performance of the pedestrian. The model provides an improvement over classic invert pendulum models. Numerical studies were undertaken to investigate the effects of leg stiffness and attack angle. Simulation results show that when walking at a given speed, increasing the leg stiffness with a constant attack angle results in a longer step length, a higher step frequency, a faster walking speed and an increase in both the peak vertical and lateral ground reaction forces. Increasing the attack angle with a constant leg stiffness results in a higher step frequency, a decrease in the step length, an increase in the total energy of the system and a decrease in both the peak vertical and lateral ground reaction forces.

  10. Research in Distributed Real-Time Systems

    NASA Technical Reports Server (NTRS)

    Mukkamala, R.

    1997-01-01

    This document summarizes the progress we have made on our study of issues concerning the schedulability of real-time systems. Our study has produced several results in the scalability issues of distributed real-time systems. In particular, we have used our techniques to resolve schedulability issues in distributed systems with end-to-end requirements. During the next year (1997-98), we propose to extend the current work to address the modeling and workload characterization issues in distributed real-time systems. In particular, we propose to investigate the effect of different workload models and component models on the design and the subsequent performance of distributed real-time systems.

  11. Reconstructing three-dimensional reentrant cardiac electrical wave dynamics using data assimilation.

    PubMed

    Hoffman, M J; LaVigne, N S; Scorse, S T; Fenton, F H; Cherry, E M

    2016-01-01

    For many years, reentrant scroll waves have been predicted and studied as an underlying mechanism for cardiac arrhythmias using numerical techniques, and high-resolution mapping studies using fluorescence recordings from the surfaces of cardiac tissue preparations have confirmed the presence of visible spiral waves. However, assessing the three-dimensional dynamics of these reentrant waves using experimental techniques has been limited to verifying stable scroll-wave dynamics in relatively thin preparations. We propose a different approach to recovering the three-dimensional dynamics of reentrant waves in the heart. By applying techniques commonly used in weather forecasting, we combine dual-surface observations from a particular experiment with predictions from a numerical model to reconstruct the full three-dimensional time series of the experiment. Here, we use model-generated surrogate observations from a numerical experiment to evaluate the performance of the ensemble Kalman filter in reconstructing such time series for a discordant alternans state in one spatial dimension and for scroll waves in three dimensions. We show that our approach is able to recover time series of both observed and unobserved variables matching the truth. Where nearby observations are available, the error is reduced below the synthetic observation error, with a smaller reduction with increased distance from observations. Our findings demonstrate that state reconstruction for spatiotemporally complex cardiac electrical dynamics is possible and will lead naturally to applications using real experimental data. PMID:26826859

  12. Three-dimensional cell to tissue development process

    NASA Technical Reports Server (NTRS)

    Goodwin, Thomas J. (Inventor); Parker, Clayton R. (Inventor)

    2008-01-01

    An improved three-dimensional cell to tissue development process using a specific time varying electromagnetic force, pulsed, square wave, with minimum fluid shear stress, freedom for 3-dimensional spatial orientation of the suspended particles and localization of particles with differing or similar sedimentation properties in a similar spatial region.

  13. Three-dimensional AOTV flowfields in chemical nonequilibrium

    NASA Technical Reports Server (NTRS)

    Gnoffo, P. A.; Mccandless, R. S.

    1986-01-01

    A technique for upwind differencing of the three-dimensional species continuity equations is presented which permits computation of steady flows in chemical equilibrium and nonequilibrium. The capabilities and shortcomings of the present approach for equilibrium and nonequilibrium flows is discussed. Modifications now being investigated to improve computational time are outlined.

  14. Three-dimensional acousto-optic spectrum analysis

    NASA Technical Reports Server (NTRS)

    Ansari, Homayoon; Metscher, Brian; Lesh, James R.

    1990-01-01

    A three-dimensional acoustooptic spectrum analyzer with subhertz resolution is demonstrated experimentally. The first and second dimensions are the two spatial dimensions of the output detector array, and the third dimension is time as sampled by the detector array frame rate. A superfine resolution of 0.12 Hz has been achieved.

  15. Quantum field between moving mirrors: A three dimensional example

    NASA Technical Reports Server (NTRS)

    Hacyan, S.; Jauregui, Roco; Villarreal, Carlos

    1995-01-01

    The scalar quantum field uniformly moving plates in three dimensional space is studied. Field equations for Dirichlet boundary conditions are solved exactly. Comparison of the resulting wavefunctions with their instantaneous static counterpart is performed via Bogolubov coefficients. Unlike the one dimensional problem, 'particle' creation as well as squeezing may occur. The time dependent Casimir energy is also evaluated.

  16. Vision in our three-dimensional world

    PubMed Central

    2016-01-01

    Many aspects of our perceptual experience are dominated by the fact that our two eyes point forward. Whilst the location of our eyes leaves the environment behind our head inaccessible to vision, co-ordinated use of our two eyes gives us direct access to the three-dimensional structure of the scene in front of us, through the mechanism of stereoscopic vision. Scientific understanding of the different brain regions involved in stereoscopic vision and three-dimensional spatial cognition is changing rapidly, with consequent influences on fields as diverse as clinical practice in ophthalmology and the technology of virtual reality devices. This article is part of the themed issue ‘Vision in our three-dimensional world’. PMID:27269595

  17. Three-dimensional separation and reattachment

    NASA Technical Reports Server (NTRS)

    Peake, D. J.; Tobak, M.

    1982-01-01

    The separation of three dimensional turbulent boundary layers from the lee of flight vehicles at high angles of attack is investigated. The separation results in dominant, large scale, coiled vortex motions that pass along the body in the general direction of the free stream. In all cases of three dimensional flow separation and reattachment, the assumption of continuous vector fields of skin friction lines and external flow streamlines, coupled with simple laws of topology, provides a flow grammar whose elemental constituents are the singular points: the nodes, spiral nodes (foci), and saddles. The phenomenon of three dimensional separation may be constrained as either a local or a global event, depending on whether the skin friction line that becomes a line of separation originates at a node or a saddle point.

  18. Topology of three-dimensional separated flows

    NASA Technical Reports Server (NTRS)

    Tobak, M.; Peake, D. J.

    1981-01-01

    Based on the hypothesis that patterns of skin-friction lines and external streamlines reflect the properties of continuous vector fields, topology rules define a small number of singular points (nodes, saddle points, and foci) that characterize the patterns on the surface and on particular projections of the flow (e.g., the crossflow plane). The restricted number of singular points and the rules that they obey are considered as an organizing principle whose finite number of elements can be combined in various ways to connect together the properties common to all steady three dimensional viscous flows. Introduction of a distinction between local and global properties of the flow resolves an ambiguity in the proper definition of a three dimensional separated flow. Adoption of the notions of topological structure, structural stability, and bifurcation provides a framework to describe how three dimensional separated flows originate and succeed each other as the relevant parameters of the problem are varied.

  19. Three-dimensional finite-difference time-domain algorithm for oblique incidence with adaptation of perfectly matched layers and nonuniform meshing: application to the study of a radar dome.

    PubMed

    Belkhir, A; Baida, F I

    2008-05-01

    The three-dimensional finite-difference time-domain (3D-FDTD) method is developed and implemented in the case of oblique incidence in order to study biperiodic structures that are finished according to the third direction. The perfectly matched layer (PML) is adapted to the developed algorithm. The electromagnetic fields of Maxwell's equations in the main grid and in the PML media are transferred from the E-H domain to the mapped P-Q domain. The modified Maxwell's equations are implemented by the split-field method (SFM). Several tests are made and presented in order to verify and demonstrate the accuracy of our codes. The obtained results are in good agreement with published ones obtained by other methods. The originality of this paper comes, first from the fact that it brings a complete development of the used algorithm, and second, from the study of the spectral response of a radar dome based on annular aperture arrays perforated into a perfect conductor plate.

  20. Update on New Tools for Three-dimensional Navigation in Endovascular Procedures

    PubMed Central

    van den Berg, Jos C.

    2014-01-01

    Three-dimensional (3D) guidance for endovascular procedures has developed over the last decade from 3D rotational angiography to the use of dynamic 3D roadmap techniques. The latest development is image merging. This technique combines real-time feedback of fluoroscopy with optimal soft-tissue contrast of previously performed computed tomography (CT) or magnetic resonance angiography. Merging of CT angiography and cone-beam CT/fluoroscopic images is feasible, and preliminary results look promising. Merging will allow us to further reduce radiation exposure, contrast dose, and procedural time, and its main use and benefit will be in complex endovascular interventions. PMID:26798746

  1. Three-Dimensional Robotic Vision System

    NASA Technical Reports Server (NTRS)

    Nguyen, Thinh V.

    1989-01-01

    Stereoscopy and motion provide clues to outlines of objects. Digital image-processing system acts as "intelligent" automatic machine-vision system by processing views from stereoscopic television cameras into three-dimensional coordinates of moving object in view. Epipolar-line technique used to find corresponding points in stereoscopic views. Robotic vision system analyzes views from two television cameras to detect rigid three-dimensional objects and reconstruct numerically in terms of coordinates of corner points. Stereoscopy and effects of motion on two images complement each other in providing image-analyzing subsystem with clues to natures and locations of principal features.

  2. Three-Dimensional Extended Bargmann Supergravity

    NASA Astrophysics Data System (ADS)

    Bergshoeff, Eric; Rosseel, Jan

    2016-06-01

    We show that three-dimensional general relativity, augmented with two vector fields, allows for a nonrelativistic limit, different from the standard limit leading to Newtonian gravity, that results in a well-defined action which is of the Chern-Simons type. We show that this three-dimensional "extended Bargmann gravity," after coupling to matter, leads to equations of motion allowing a wider class of background geometries than the ones that one encounters in Newtonian gravity. We give the supersymmetric generalization of these results and point out an important application in the context of calculating partition functions of nonrelativistic field theories using localization techniques.

  3. Three-Dimensional Extended Bargmann Supergravity.

    PubMed

    Bergshoeff, Eric; Rosseel, Jan

    2016-06-24

    We show that three-dimensional general relativity, augmented with two vector fields, allows for a nonrelativistic limit, different from the standard limit leading to Newtonian gravity, that results in a well-defined action which is of the Chern-Simons type. We show that this three-dimensional "extended Bargmann gravity," after coupling to matter, leads to equations of motion allowing a wider class of background geometries than the ones that one encounters in Newtonian gravity. We give the supersymmetric generalization of these results and point out an important application in the context of calculating partition functions of nonrelativistic field theories using localization techniques. PMID:27391712

  4. Three-Dimensional Icosahedral Phase Field Quasicrystal.

    PubMed

    Subramanian, P; Archer, A J; Knobloch, E; Rucklidge, A M

    2016-08-12

    We investigate the formation and stability of icosahedral quasicrystalline structures using a dynamic phase field crystal model. Nonlinear interactions between density waves at two length scales stabilize three-dimensional quasicrystals. We determine the phase diagram and parameter values required for the quasicrystal to be the global minimum free energy state. We demonstrate that traits that promote the formation of two-dimensional quasicrystals are extant in three dimensions, and highlight the characteristics required for three-dimensional soft matter quasicrystal formation. PMID:27563973

  5. Two- and three-dimensional blade vortex interactions

    NASA Technical Reports Server (NTRS)

    Davoudzadeh, F.; Liu, N.-S; Briley, W. R.; Buggeln, R. C.; Shamroth, S. J.

    1990-01-01

    A three-dimensional time dependent Navier-Stokes analysis was applied to the rotor blade vortex interaction (BVI) problem. The numerical procedure is an iterative implicit procedure using three point central differences to represent spatial derivatives. A series of calculations were made to determine the time steps, pseudo-time steps, iterations, artificial dissipation level, etc. required to maintain a nondissipative vortex. Results show the chosen method to have excellent non-dissipative properties provided the correct parameters are chosen. This study was used to set parameters for both two- and three-dimensional blade vortex interaction studies. The two-dimensional study considered the interaction between a vortex and a NACA0012 airfoil. The results showed the detailed physics during the interaction including the pressure pulse propagating from the blade. The simulated flow physics was qualitatively similar to that experimentally observed. The 2-D BVI phenomena is the result of the buildup and violent collapse of the shock waves and local supersonic pockets on the blade surfaces. The resulting pressure pulse build-up appears to be centered at the blade leading edge. The three-dimensional interaction study considered the case of a vortex at 20 deg incidence to the blade leading edge. Although the qualitative results were similar to that of the two-dimensional interaction, details clearly showed the three-dimensional nature of the interaction process.

  6. Study of the Three-dimensional Coronal Magnetic Field of Active Region 11117 around the Time of a Confined Flare Using a Data-Driven CESE-MHD Model

    NASA Astrophysics Data System (ADS)

    Jiang, Chaowei; Feng, Xueshang; Wu, S. T.; Hu, Qiang

    2012-11-01

    We apply a data-driven magnetohydrodynamics (MHD) model to investigate the three-dimensional (3D) magnetic field of NOAA active region (AR) 11117 around the time of a C-class confined flare that occurred on 2010 October 25. The MHD model, based on the spacetime conservation-element and solution-element scheme, is designed to focus on the magnetic field evolution and to consider a simplified solar atomsphere with finite plasma β. Magnetic vector-field data derived from the observations at the photosphere is inputted directly to constrain the model. Assuming that the dynamic evolution of the coronal magnetic field can be approximated by successive equilibria, we solve a time sequence of MHD equilibria based on a set of vector magnetograms for AR 11117 taken by the Helioseismic and Magnetic Imager on board the Solar Dynamic Observatory around the time of the flare. The model qualitatively reproduces the basic structures of the 3D magnetic field, as supported by the visual similarity between the field lines and the coronal loops observed by the Atmospheric Imaging Assembly, which shows that the coronal field can indeed be well characterized by the MHD equilibrium in most cases. The magnetic configuration changes very little during the studied time interval of 2 hr. A topological analysis reveals that the small flare is correlated with a bald patch (BP, where the magnetic field is tangent to the photosphere), suggesting that the energy release of the flare can be understood by magnetic reconnection associated with the BP separatrices. The total magnetic flux and energy keep increasing slightly in spite of the flare, while the computed magnetic free energy drops during the flare by ~1030 erg, which seems to be adequate in providing the energy budget of a minor C-class confined flare.

  7. STUDY OF THE THREE-DIMENSIONAL CORONAL MAGNETIC FIELD OF ACTIVE REGION 11117 AROUND THE TIME OF A CONFINED FLARE USING A DATA-DRIVEN CESE-MHD MODEL

    SciTech Connect

    Jiang Chaowei; Feng Xueshang; Wu, S. T.; Hu Qiang E-mail: fengx@spaceweather.ac.cn E-mail: qh0001@uah.edu

    2012-11-10

    We apply a data-driven magnetohydrodynamics (MHD) model to investigate the three-dimensional (3D) magnetic field of NOAA active region (AR) 11117 around the time of a C-class confined flare that occurred on 2010 October 25. The MHD model, based on the spacetime conservation-element and solution-element scheme, is designed to focus on the magnetic field evolution and to consider a simplified solar atomsphere with finite plasma {beta}. Magnetic vector-field data derived from the observations at the photosphere is inputted directly to constrain the model. Assuming that the dynamic evolution of the coronal magnetic field can be approximated by successive equilibria, we solve a time sequence of MHD equilibria based on a set of vector magnetograms for AR 11117 taken by the Helioseismic and Magnetic Imager on board the Solar Dynamic Observatory around the time of the flare. The model qualitatively reproduces the basic structures of the 3D magnetic field, as supported by the visual similarity between the field lines and the coronal loops observed by the Atmospheric Imaging Assembly, which shows that the coronal field can indeed be well characterized by the MHD equilibrium in most cases. The magnetic configuration changes very little during the studied time interval of 2 hr. A topological analysis reveals that the small flare is correlated with a bald patch (BP, where the magnetic field is tangent to the photosphere), suggesting that the energy release of the flare can be understood by magnetic reconnection associated with the BP separatrices. The total magnetic flux and energy keep increasing slightly in spite of the flare, while the computed magnetic free energy drops during the flare by {approx}10{sup 30} erg, which seems to be adequate in providing the energy budget of a minor C-class confined flare.

  8. Three-dimensional ring current decay model

    NASA Astrophysics Data System (ADS)

    Fok, Mei Ching; Moore, Thomas E.; Kozyra, Janet U.; Ho, George C.; Hamilton, Douglas C.

    1995-06-01

    This work is an extension of a previous ring current decay model. In the previous work, a two-dimensional kinetic model was constructed to study the temporal variations of the equatorially mirroring ring current ions, considering charge exchange and Coulomb drag losses along drift paths in a magnetic dipole field. In this work, particles with arbitrary pitch angle are considered. By bounce averaging the kinetic equation of the phase space density, information along magnetic field lines can be inferred from the equator. The three-dimensional model is used to simulate the recovery phase of a model great magnetic storm, similar to that which occurred in early February 1986. The initial distribution of ring current ions (at the minimum Dst) is extrapolated to all local times from AMPTE/CCE spacecraft observations on the dawnside and duskside of the inner magnetosphere spanning the L value range L=2.25 to 6.75. Observations by AMPTE/CCE of ring current distributions over subsequent orbits during the storm recovery phase are compared to model outputs. In general, the calculated ion fluxes are consistent with observations, except for H+ fluxes at tens of keV, which are always overestimated. A newly invented visualization idea, designated as a chromogram, is used to display the spatial and energy dependence of the ring current ion diifferential flux. Important features of storm time ring current, such as day-night asymmetry during injection and drift hole on the dayside at low energies (<10 keV), are manifested in the chromogram representation. The pitch angle distribution is well fit by the function, j0(1+Ayn), where y is sine of the equatorial pitch angle. The evolution of the index n is a combined effect of charge exchange loss and particle drift. At low energies (<30 keV), both drift dispersion and charge exchange are important in determining n. ©American Geophysical 1995

  9. Three-dimensional ring current decay model

    NASA Technical Reports Server (NTRS)

    Fok, Mei-Ching; Moore, Thomas E.; Kozyra, Janet U.; Ho, George C.; Hamilton, Douglas C.

    1995-01-01

    This work is an extension of a previous ring current decay model. In the previous work, a two-dimensional kinetic model was constructed to study the temporal variations of the equatorially mirroring ring current ions, considering charge exchange and Coulomb drag losses along drift paths in a magnetic dipole field. In this work, particles with arbitrary pitch angle are considered. By bounce averaging the kinetic equation of the phase space density, information along magnetic field lines can be inferred from the equator. The three-dimensional model is used to simulate the recovery phase of a model great magnetic storm, similar to that which occurred in early February 1986. The initial distribution of ring current ions (at the minimum Dst) is extrapolated to all local times from AMPTE/CCE spacecraft observations on the dawnside and duskside of the inner magnetosphere spanning the L value range L = 2.25 to 6.75. Observations by AMPTE/CCE of ring current distributions over subsequent orbits during the storm recovery phase are compared to model outputs. In general, the calculated ion fluxes are consistent with observations, except for H(+) fluxes at tens of keV, which are always overestimated. A newly invented visualization idea, designated as a chromogram, is used to display the spatial and energy dependence of the ring current ion differential flux. Important features of storm time ring current, such as day-night asymmetry during injection and drift hole on the dayside at low energies (less than 10 keV), are manifested in the chromogram representation. The pitch angle distribution is well fit by the function, J(sub o)(1 + Ay(sup n)), where y is sine of the equatorial pitch angle. The evolution of the index n is a combined effect of charge exchange loss and particle drift. At low energies (less than 30 keV), both drift dispersion and charge exchange are important in determining n.

  10. Hand-held optoacoustic probe for three-dimensional imaging of human morphology and function

    NASA Astrophysics Data System (ADS)

    Deán-Ben, X. Luís.; Razansky, Daniel

    2014-03-01

    We report on a hand-held imaging probe for real-time optoacoustic visualization of deep tissues in three dimensions. The proposed solution incorporates a two-dimensional array of ultrasonic sensors densely distributed on a spherical surface, whereas illumination is performed coaxially through a cylindrical cavity in the array. Visualization of three-dimensional tomographic data at a frame rate of 10 images per second is enabled by parallel recording of 256 time-resolved signals for each individual laser pulse along with a highly efficient GPUbased real-time reconstruction. A liquid coupling medium (water), enclosed in a transparent membrane, is used to guarantee transmission of the optoacoustically generated waves to the ultrasonic detectors. Excitation at multiple wavelengths further allows imaging spectrally distinctive tissue chromophores such as oxygenated and deoxygenated haemoglobin. The performance is showcased by video-rate tracking of deep tissue vasculature and three-dimensional measurements of blood oxygenenation in a healthy human volunteer. The flexibility provided by the hand-held hardware design, combined with the real-time operation, makes the developed platform highly usable for both small animal research and clinical imaging in multiple indications, including cancer, inflammation, skin and cardiovascular diseases, diagnostics of lymphatic system and breast

  11. Combined Labelled and Label-free SERS Probes for Triplex Three-dimensional Cellular Imaging

    NASA Astrophysics Data System (ADS)

    Chen, Yong; Bai, Xiangru; Su, Le; Du, Zhanwei; Shen, Aiguo; Materny, Arnulf; Hu, Jiming

    2016-01-01

    Cells are complex chemical systems, where the molecular composition at different cellular locations and specific intracellular chemical interactions determine the biological function. An in-situ nondestructive characterization of the complicated chemical processes (like e.g. apoptosis) is the goal of our study. Here, we present the results of simultaneous and three-dimensional imaging of double organelles (nucleus and membrane) in single HeLa cells by means of either labelled or label-free surface-enhanced Raman spectroscopy (SERS). This combination of imaging with and without labels is not possible when using fluorescence microscopy. The SERS technique is used for a stereoscopic description of the intrinsic chemical nature of nuclei and the precise localization of folate (FA) and luteinizing hormone-releasing hormone (LHRH) on the membrane under highly confocal conditions. We also report on the time-dependent changes of cell nuclei as well as membrane receptor proteins during apoptosis analyzed by statistical multivariate methods. The multiplex three-dimensional SERS imaging technique allows for both temporal (real time) and spatial (multiple organelles and molecules in three-dimensional space) live-cell imaging and therefore provides a new and attractive 2D/3D tracing method in biomedicine on subcellular level.

  12. Combined Labelled and Label-free SERS Probes for Triplex Three-dimensional Cellular Imaging

    PubMed Central

    Chen, Yong; Bai, Xiangru; Su, Le; Du, Zhanwei; Shen, Aiguo; Materny, Arnulf; Hu, Jiming

    2016-01-01

    Cells are complex chemical systems, where the molecular composition at different cellular locations and specific intracellular chemical interactions determine the biological function. An in-situ nondestructive characterization of the complicated chemical processes (like e.g. apoptosis) is the goal of our study. Here, we present the results of simultaneous and three-dimensional imaging of double organelles (nucleus and membrane) in single HeLa cells by means of either labelled or label-free surface-enhanced Raman spectroscopy (SERS). This combination of imaging with and without labels is not possible when using fluorescence microscopy. The SERS technique is used for a stereoscopic description of the intrinsic chemical nature of nuclei and the precise localization of folate (FA) and luteinizing hormone-releasing hormone (LHRH) on the membrane under highly confocal conditions. We also report on the time-dependent changes of cell nuclei as well as membrane receptor proteins during apoptosis analyzed by statistical multivariate methods. The multiplex three-dimensional SERS imaging technique allows for both temporal (real time) and spatial (multiple organelles and molecules in three-dimensional space) live-cell imaging and therefore provides a new and attractive 2D/3D tracing method in biomedicine on subcellular level. PMID:26781186

  13. Real time programming environment for Windows

    SciTech Connect

    LaBelle, D.R.

    1998-04-01

    This document provides a description of the Real Time Programming Environment (RTProE). RTProE tools allow a programmer to create soft real time projects under general, multi-purpose operating systems. The basic features necessary for real time applications are provided by RTProE, leaving the programmer free to concentrate efforts on his specific project. The current version supports Microsoft Windows{trademark} 95 and NT. The tasks of real time synchronization and communication with other programs are handled by RTProE. RTProE includes a generic method for connecting a graphical user interface (GUI) to allow real time control and interaction with the programmer`s product. Topics covered in this paper include real time performance issues, portability, details of shared memory management, code scheduling, application control, Operating System specific concerns and the use of Computer Aided Software Engineering (CASE) tools. The development of RTProE is an important step in the expansion of the real time programming community. The financial costs associated with using the system are minimal. All source code for RTProE has been made publicly available. Any person with access to a personal computer, Windows 95 or NT, and C or FORTRAN compilers can quickly enter the world of real time modeling and simulation.

  14. Combinatorial thin film composition mapping using three dimensional deposition profiles

    NASA Astrophysics Data System (ADS)

    Suram, Santosh K.; Zhou, Lan; Becerra-Stasiewicz, Natalie; Kan, Kevin; Jones, Ryan J. R.; Kendrick, Brian M.; Gregoire, John M.

    2015-03-01

    Many next-generation technologies are limited by material performance, leading to increased interest in the discovery of advanced materials using combinatorial synthesis, characterization, and screening. Several combinatorial synthesis techniques, such as solution based methods, advanced manufacturing, and physical vapor deposition, are currently being employed for various applications. In particular, combinatorial magnetron sputtering is a versatile technique that provides synthesis of high-quality thin film composition libraries. Spatially addressing the composition of these thin films generally requires elemental quantification measurements using techniques such as energy-dispersive X-ray spectroscopy or X-ray fluorescence spectroscopy. Since these measurements are performed ex-situ and post-deposition, they are unable to provide real-time design of experiments, a capability that is required for rapid synthesis of a specific composition library. By using three quartz crystal monitors attached to a stage with translational and rotational degrees of freedom, we measure three-dimensional deposition profiles of deposition sources whose tilt with respect to the substrate is robotically controlled. We exhibit the utility of deposition profiles and tilt control to optimize the deposition geometry for specific combinatorial synthesis experiments.

  15. Three-dimensionally assembled gold nanostructures for plasmonic biosensors.

    PubMed

    Guo, Longhua; Chen, Guonan; Kim, Dong-Hwan

    2010-06-15

    Three-dimensional gold nanoarchitecture was fabricated by layer-by-layer (LbL) deposition of gold nanoparticles (AuNPs) and multiwalled carbon nanotubes (MWCNTs) on a glass substrate for a highly sensitive plasmonic biosensor using a conventional UV-vis instrument. Carboxyl-functionalized MWCNTs were reacted with 3-mercaptopropyltriethoxysilane (MPTES) to introduce multiple thiol groups onto MWCNTs. A self-assembled monolayer (SAM) of AuNPs on a glass chip was sequentially dipped into MPTES-functionalized MWCNTs (MWCNT-Si-SH) and AuNPs to form multilayers of AuNPs on MWCNTs. Such three-dimensionally assembled AuNPs provided a large surface area and multiple binding sites within a few steps of modification and microporous structures of multilayered MWCNTs to allow a high accessibility of target molecules. It was shown that the bulk refractive index (RI) sensitivity of these multilayered AuNPs (three-dimensional chip) appeared to be 5.6 times better than that of a monolayer of AuNPs on a glass chip (two-dimensional chip). The three-dimensional chips were further used for a biomolecular binding study, showing a detection limit as low as 0.5 nM for streptavidin and 3.33 nM for anti-human serum albumin (HSA), both of which were approximately 20 times higher than the sensitivity of the two-dimensional chips.

  16. A DETERMINISTIC METHOD FOR TRANSIENT, THREE-DIMENSIONAL NUETRON TRANSPORT

    SciTech Connect

    Goluoglu, S.; Bentley, C.; Demeglio, R.; Dunn, M.; Norton, K.; Pevey, R.; Suslov, I.; Dodds, H. L.

    1998-01-14

    A deterministic method for solving the time-dependent, three-dimensional Boltzmam transport equation with explicit representation of delayed neutrons has been developed and evaluated. The methodology used in this study for the time variable of the neutron flux is known as the improved quasi-static (IQS) method. The position, energy, and angle-dependent neutron flux is computed deterministically by using the three-dimensional discrete ordinates code TORT. This paper briefly describes the methodology and selected results. The code developed at the University of Tennessee based on this methodology is called TDTORT. TDTORT can be used to model transients involving voided and/or strongly absorbing regions that require transport theory for accuracy. This code can also be used to model either small high-leakage systems, such as space reactors, or asymmetric control rod movements. TDTORT can model step, ramp, step followed by another step, and step followed by ramp type perturbations. It can also model columnwise rod movement can also be modeled. A special case of columnwise rod movement in a three-dimensional model of a boiling water reactor (BWR) with simple adiabatic feedback is also included. TDTORT is verified through several transient one-dimensional, two-dimensional, and three-dimensional benchmark problems. The results show that the transport methodology and corresponding code developed in this work have sufficient accuracy and speed for computing the dynamic behavior of complex multidimensional neutronic systems.

  17. A deterministic method for transient, three-dimensional neutron transport

    SciTech Connect

    Goluoglu, S.; Bentley, C.; DeMeglio, R.; Dunn, M.; Norton, K.; Pevey, R.; Suslov, I.; Dodds, H.L.

    1998-05-01

    A deterministic method for solving the time-dependent, three-dimensional Boltzmann transport equation with explicit representation of delayed neutrons has been developed and evaluated. The methodology used in this study for the time variable of the neutron flux is known as the improved quasi-static (IQS) method. The position, energy, and angle-dependent neutron flux is computed deterministically by using the three-dimensional discrete ordinates code TORT. This paper briefly describes the methodology and selected results. The code developed at the University of Tennessee based on this methodology is called TDTORT. TDTORT can be used to model transients involving voided and/or strongly absorbing regions that require transport theory for accuracy. This code can also be used to model either small high-leakage systems, such as space reactors, or asymmetric control rod movements. TDTORT can model step, ramp, step followed by another step, and step followed by ramp type perturbations. It can also model columnwise rod movement. A special case of columnwise rod movement in a three-dimensional model of a boiling water reactor (BWR) with simple adiabatic feedback is also included. TDTORT is verified through several transient one-dimensional, two-dimensional, and three-dimensional benchmark problems. The results show that the transport methodology and corresponding code developed in this work have sufficient accuracy and speed for computing the dynamic behavior of complex multi-dimensional neutronic systems.

  18. Modern cosmology and the origin of our three dimensionality.

    PubMed

    Woodbury, M A; Woodbury, M F

    1998-01-01

    We are three dimensional egocentric beings existing within a specific space/time continuum and dimensionality which we assume wrongly is the same for all times and places throughout the entire universe. Physicists name Omnipoint the origin of the universe at Dimension zero, which exploded as a Big Bang of energy proceeding at enormous speed along one dimension which eventually curled up into matter: particles, atoms, molecules and Galaxies which exist in two dimensional space. Finally from matter spread throughout the cosmos evolved life generating eventually the DNA molecules which control the construction of brains complex enough to construct our three dimensional Body Representation from which is extrapolated what we perceive as a 3-D universe. The whole interconnected structures which conjure up our three dimensionality are as fragile as Humpty Dumpty, capable of breaking apart with terrifying effects for the individual patient during a psychotic panic, revealing our three dimensionality to be but "maya", an illusion, which we psychiatrists work at putting back together.

  19. Three-dimensional ultrasound imaging of the vasculature.

    PubMed

    Fenster, A; Lee, D; Sherebrin, S; Rankin, R; Downey, D

    1998-02-01

    With conventional ultrasonography, the diagnostician must view a series of two-dimensional images in order to form a mental impression of the three-dimensional anatomy, an efficient and time consuming practice prone to operator variability, which may cause variable or even incorrect diagnoses. Also, a conventional two-dimensional ultrasound image represents a thin slice of the patients anatomy at a single location and orientation, which is difficult to reproduce at a later time. These factors make conventional ultrasonography non-optimal for prospective or follow-up studies. Our efforts have focused on overcoming these deficiencies by developing three-dimensional ultrasound imaging techniques that are capable of acquiring B-mode, colour Doppler and power Doppler images of the vasculature, by using a conventional ultrasound system to acquire a series of two-dimensional images and then mathematically reconstructing them into a single three-dimensional image, which may then be viewed interactively on an inexpensive desktop computer. We report here on two approaches: (1) free-hand scanning, in which a magnetic positioning device is attached to the ultrasound transducer to record the position and orientation of each two-dimensional image needed for the three-dimensional image reconstruction; and (2) mechanical scanning, in which a motor-driven assembly is used to translate the transducer linearly across the neck, yielding a set of uniformly-spaced parallel two-dimensional images.

  20. Three-Dimensional Printing Surgical Applications

    PubMed Central

    Griffin, Michelle F.; Butler, Peter E.

    2015-01-01

    Introduction: Three-dimensional printing, a technology used for decades in the industrial field, gains a lot of attention in the medical field for its potential benefits. With advancement of desktop printers, this technology is accessible and a lot of research is going on in the medical field. Objective: To evaluate its application in surgical field, which may include but not limited to surgical planning, surgical education, implants, and prosthesis, which are the focus of this review. Methods: Research was conducted by searching PubMed, Web of science, and other reliable sources. We included original articles and excluded articles based on animals, those more than 10 years old, and those not in English. These articles were evaluated, and relevant studies were included in this review. Discussion: Three-dimensional printing shows a potential benefit in surgical application. Printed implants were used in patient in a few cases and show successful results; however, longer follow-up and more trials are needed. Surgical and medical education is believed to be more efficient with this technology than the current practice. Printed surgical instrument and surgical planning are also believed to improve with three-dimensional printing. Conclusion: Three-dimensional printing can be a very powerful tool in the near future, which can aid the medical field that is facing a lot of challenges and obstacles. However, despite the reported results, further research on larger samples and analytical measurements should be conducted to ensure this technology's impact on the practice. PMID:26301002

  1. Three Dimensional Display Of Meteorological Scientific Data

    NASA Astrophysics Data System (ADS)

    Grotch, Stanley L.

    1988-01-01

    Even a cursory reading of any daily newspaper shows that we are in the midst of a dramatic revolution in computer graphics. Virtually every day some new piece of hardware or software is announced, adding to the tools available to the working scientist. Three dimensional graphics form a significant part of this revolution having become virtually commonplace in advertising and on television.

  2. Three-dimensional colorimetric assay assemblies

    DOEpatents

    Charych, Deborah; Reichert, Anke

    2001-01-01

    A direct assay is described using novel three-dimensional polymeric assemblies which change from a blue to red color when exposed to an analyte, in one case a flue virus. The assemblies are typically in the form of liposomes which can be maintained in a suspension, and show great intensity in their color changes. Their method of production is also described.

  3. Modification of a commercial thromboelastography instrument to measure coagulation dynamics with three-dimensional biomaterials.

    PubMed

    Hawker, Morgan J; Olver, Christine S; Fisher, Ellen R

    2016-06-01

    Three-dimensional synthetic constructs with complex geometries have immense potential for use in a multitude of blood-contacting applications. Understanding coagulation phenomena is arguably the most critical aspect for applications involving synthetic biomaterials; however, real-time evaluation of the clot formation while interfacing with these materials is difficult to achieve in a reproducible and robust manner. Here, work representing first steps toward addressing this deficit is presented, wherein modified consumables for a clinical instrument (a Thromboelastograph(®)) have been fabricated. Thromboelastography (TEG) measures viscoelastic properties throughout clot formation and therefore provides clinically relevant coagulation measurements in real time (i.e., kinetics and strength of clot formation). Through our modification, TEG consumables can readily accommodate three-dimensional materials (e.g., those for regenerative tissue applications). The authors performed proof-of-concept experiments using polymer scaffolds with a range of surface properties and demonstrated that variations in surface properties resulted in differences in blood plasma coagulation dynamics. For example, the maximum rate of thrombus generation ranged from 22.2 ± 2.2 (dyn/cm(2))/s for fluorocarbon coated scaffolds to 8.7 ± 1.0 (dyn/cm(2))/s for nitrogen-containing scaffolds. Through this work, the ability to make real-time coagulation activity measurements during constant coagulation factor interface with biomedically relevant materials is demonstrated. PMID:27126596

  4. Biosensing capability of gold-nanoparticle- immobilized three-dimensionally ordered macroporous film

    NASA Astrophysics Data System (ADS)

    Chen, H.-H.; Suzuki, H.; Sato, O.; Gu, Z.-Z.

    2005-11-01

    A new type of biosensor was fabricated by coating gold nanoparticles onto a film with a three-dimensionally ordered macroporous (3DOM) structure. It was found that the localized surface plasmon resonance of the immobilized nanoparticles changes with the infiltration medium inside the voids of the 3DOM film and the surface-adsorbed compounds. Application of this type of film to the real-time detection of immunoreaction was demonstrated. It is anticipated that this kind of film will have applications in label-free biosensors.

  5. Technical aspects of a demonstration tape for three-dimensional sound displays

    NASA Technical Reports Server (NTRS)

    Begault, Durand R.; Wenzel, Elizabeth M.

    1990-01-01

    This document was developed to accompany an audio cassette that demonstrates work in three-dimensional auditory displays, developed at the Ames Research Center Aerospace Human Factors Division. It provides a text version of the audio material, and covers the theoretical and technical issues of spatial auditory displays in greater depth than on the cassette. The technical procedures used in the production of the audio demonstration are documented, including the methods for simulating rotorcraft radio communication, synthesizing auditory icons, and using the Convolvotron, a real-time spatialization device.

  6. Research of real-time communication software

    NASA Astrophysics Data System (ADS)

    Li, Maotang; Guo, Jingbo; Liu, Yuzhong; Li, Jiahong

    2003-11-01

    Real-time communication has been playing an increasingly important role in our work, life and ocean monitor. With the rapid progress of computer and communication technique as well as the miniaturization of communication system, it is needed to develop the adaptable and reliable real-time communication software in the ocean monitor system. This paper involves the real-time communication software research based on the point-to-point satellite intercommunication system. The object-oriented design method is adopted, which can transmit and receive video data and audio data as well as engineering data by satellite channel. In the real-time communication software, some software modules are developed, which can realize the point-to-point satellite intercommunication in the ocean monitor system. There are three advantages for the real-time communication software. One is that the real-time communication software increases the reliability of the point-to-point satellite intercommunication system working. Second is that some optional parameters are intercalated, which greatly increases the flexibility of the system working. Third is that some hardware is substituted by the real-time communication software, which not only decrease the expense of the system and promotes the miniaturization of communication system, but also aggrandizes the agility of the system.

  7. The ALMA Real Time Control System

    NASA Astrophysics Data System (ADS)

    Kern, Jeffrey S.; Juerges, Thomas A.; Marson, Ralph G.

    2009-01-01

    The Atacama Large Millimeter Array (ALMA) is a revolutionary millimeter and submillimeter array being developed on the Atacama plateau of northern Chile. An international partnership lead by NRAO, ESO, and NAOJ this powerful and flexible telescope will provide unprecedented observations of this relatively unexplored frequency range. The control subsystem for the Atacama Large Millimeter Array must coordinate the monitor and control of at least sixty six antennas (in four different styles), two correlators, and all of the ancillary equipment (samplers, local oscillators, front ends, etc.). This equipment will be spread over tens of kilometers and operated remotely. Operation of the array requires a robust, scalable, and maintainable real time control system. The real time control system is responsible for monitoring and control of any devices where there are fixed deadlines. Examples in the ALMA context are antenna pointing and fringe tracking. Traditionally the real time portion of a large software system is an intricate and error prone portion of the software. As a result the real time portion is very expensive in terms of effort expended both during construction and during maintenance phases of a project. The ALMA real time control system uses a Linux based real time operating system to interact with the hardware and the CORBA based ALMA Common Software to communicate in the distributed computing environment. Mixing the requirements of real time computing and the non-deterministic CORBA middleware has produced an interesting design. We discuss the architecture, design, and implementation of the ALMA real time control system. Highlight some lessons learned along the way, and justify our assertion that this should be the last large scale real time control system in radio astronomy.

  8. Real time sensor for therapeutic radiation delivery

    DOEpatents

    Bliss, Mary; Craig, Richard A.; Reeder, Paul L.

    1998-01-01

    The invention is a real time sensor for therapeutic radiation. A probe is placed in or near the patient that senses in real time the dose at the location of the probe. The strength of the dose is determined by either an insertion or an exit probe. The location is determined by a series of vertical and horizontal sensing elements that gives the operator a real time read out dose location relative to placement of the patient. The increased accuracy prevents serious tissue damage to the patient by preventing overdose or delivery of a dose to a wrong location within the body.

  9. Real time sensor for therapeutic radiation delivery

    DOEpatents

    Bliss, M.; Craig, R.A.; Reeder, P.L.

    1998-01-06

    The invention is a real time sensor for therapeutic radiation. A probe is placed in or near the patient that senses in real time the dose at the location of the probe. The strength of the dose is determined by either an insertion or an exit probe. The location is determined by a series of vertical and horizontal sensing elements that gives the operator a real time read out dose location relative to placement of the patient. The increased accuracy prevents serious tissue damage to the patient by preventing overdose or delivery of a dose to a wrong location within the body. 14 figs.

  10. Real-time monitoring of landslides

    USGS Publications Warehouse

    Reid, Mark E.; LaHusen, Richard G.; Baum, Rex L.; Kean, Jason W.; Schulz, William H.; Highland, Lynn M.

    2012-01-01

    Landslides cause fatalities and property damage throughout the Nation. To reduce the impact from hazardous landslides, the U.S. Geological Survey develops and uses real-time and near-real-time landslide monitoring systems. Monitoring can detect when hillslopes are primed for sliding and can provide early indications of rapid, catastrophic movement. Continuous information from up-to-the-minute or real-time monitoring provides prompt notification of landslide activity, advances our understanding of landslide behavior, and enables more effective engineering and planning efforts.

  11. Real-time medical applications and telecommunications.

    PubMed

    Stravs, M

    1999-01-01

    Telecommunications play an important role in telemedicine. Many forms of telecommunication services based on different telecommunication technologies are developed for various needs. The paper deals with complex real-time applications which demand high telecommunication requirements. At the beginning, medical applications are categorised and real-time applications qualified as multimedia applications. Requirements for multimedia elements are listed separately. Later on, short introduction of related telecommunication protocols is given. Real-time medical applications can show their ability in case of guaranteed quality of services delivered by telecommunication network as it is explained in the end.

  12. Three dimensional modelling of ICRF launchers for fusion devices

    NASA Astrophysics Data System (ADS)

    Carter, M. D.; Rasmussen, D. A.; Ryan, P. M.; Hanson, G. R.; Stallings, D. C.; Batchelor, D. B.; Bigelow, T. S.; England, A. C.; Hoffman, D. J.; Murakami, M.; Wang, C. Y.; Wilgen, J. B.; Rogers, J. H.; Wilson, J. R.; Majeski, R.; Schilling, G.

    1996-02-01

    The three dimensional (3-D) nature of antennas for fusion applications in the ion cyclotron range of frequencies (ICRF) requires accurate modelling to design and analyse new antennas. In this article, analysis and design tools for radiofrequency (RF) antennas are successfully benchmarked with experiment, and the 3-D physics of the launched waves is explored. The systematic analysis combines measured density profiles from a reflectometer system, transmission line circuit modelling, detailed 3-D magnetostatics modelling and a new 3-D electromagnetic antenna model including plasma. This analysis gives very good agreement with measured loading data from the Tokamak Fusion Test Reactor (TFTR) Bay-M antenna, thus demonstrating the validity of the analysis for the design of new RF antennas. The 3-D modelling is contrasted with 2-D models, and significant deficiencies are found in the latter. The 2-D models are in error by as much as a factor of 2 in real and reactive loading, even after they are corrected for the most obvious 3-D effects. Three dimensional effects play the most significant role at low parallel wavenumbers, where the launched power spectrum can be quite different from the predictions of 2-D models. Three dimensional effects should not be ignored for many RF designs, especially those intended for fast wave current drive

  13. Expression of osteoblastic phenotype in periodontal ligament fibroblasts cultured in three-dimensional collagen gel

    PubMed Central

    ALVES, Luciana Bastos; MARIGUELA, Viviane Casagrande; GRISI, Márcio Fernando de Moraes; de SOUZA, Sérgio Luiz Scaombatti; NOVAES, Arthur Belém; TABA, Mário; de OLIVEIRA, Paulo Tambasco; PALIOTO, Daniela Bazan

    2015-01-01

    Objective : To investigate the influence of a three-dimensional cell culture model on the expression of osteoblastic phenotype in human periodontal ligament fibroblast (hPDLF) cultures. Material and Methods : hPDLF were seeded on bi-dimensional (2D) and three-dimensional (3D) collagen type I (experimental groups) and and on a plastic coverslip (control) for up to 14 days. Cell viability and alkaline phosphatase (ALP) activity were performed. Also, cell morphology and immunolabeling for alkaline phosphatase (ALP) and osteopontin (OPN) were assessed by epifluorescence and confocal microscopy. The expression of osteogenic markers, including alkaline phosphatase, osteopontin, osteocalcin (OC), collagen I (COL I) and runt-related transcription factor 2 (RUNX2), were analyzed using real-time polymerase chain reaction (RT-PCR). Mineralized bone-like nodule formation was visualized by microscopy and calcium content was assessed quantitatively by alizarin red assay. Results : Experimental cultures produced an increase in cell proliferation. Immunolabeling for OPN and ALP in hPDLF were increased and ALP activity was inhibited by three-dimensional conditions. OPN and RUNX2 gene expression was significantly higher on 3D culture when compared with control surface. Moreover, ALP and COL I gene expression were significantly higher in three-dimensional collagen than in 2D cultures at 7 days. However, at 14 days, 3D cultures exhibited ALP and COL I gene expression significantly lower than the control, and the COL I gene expression was also significantly lower in 3D than in 2D cultures. Significant calcium mineralization was detected and quantified by alizarin red assay, and calcified nodule formation was not affected by tridimensionality. Conclusion : This study suggests that the 3D cultures are able to support hPDLF proliferation and favor the differentiation and mineralized matrix formation, which may be a potential periodontal regenerative therapy. PMID:26018313

  14. Geodynamic monitoring in real times

    NASA Astrophysics Data System (ADS)

    Outkin, V.; Yurkov, A.; Klimshin, A.; Kozlova, I.

    2011-12-01

    For the decision of problems of the short-term and intermediate term forecast of tectonic earthquakes the technique conditionally named - geodynamic monitoring which does not use the data of seismic monitoring for the operative decision of problems of the forecast is offered. Geodynamic monitoring (GDM) is to studying tensely - deformed conditions of the separate block of rock on change of activity natural radioactive gas is carried out by accommodation in the chosen file of specially designed monitors of radon - devices fixing change in time (VAR). The monitor of radon, (the detector of radon) as the basic measuring device located in the block of rocks, possesses enormous tensosensitivity to relative strain condition of a file. Depending on the enclosed pressure choose three characteristic points: 1) 30-35 % of "background" size VAR - the beginning of accumulation of inelastic energy; 2) 50 % of background VAR - the process of stabilization of an elastic condition of a file; 3) 70-75 % "background" VAR - a critical pressure in the mountain block, an opportunity as spontaneous dump of elastic energy, and under action external "triggerring" forces. If the size of the saved up energy is close to critical dump needs energy at a level of energy of variations of rotation of the Earth. Such significant energy causes "plenty" of earthquakes on all planet simultaneously. This fact confirms an opportunity of the short-term forecast of strong (destructive) earthquakes: dump of elastic pressure of the Earth in this case occurs in 25-30 hours after passage of variations of rotation of the Earth. It is for the notification of the population about coming nearer earthquake. External power functions (mechanical, electromagnetic, etc.), preparations influencing system and occurrence of tectonic earthquakes, are divided on two big classes: 1) "forecasting " functions - processes functionally connected to accumulation of elastic pressure and to dump by its rather small dozes; 2

  15. Artifacts in three-dimensional transesophageal echocardiography.

    PubMed

    Faletra, Francesco Fulvio; Ramamurthi, Alamelu; Dequarti, Maria Cristina; Leo, Laura Anna; Moccetti, Tiziano; Pandian, Natesa

    2014-05-01

    Three-dimensional (3D) transesophageal echocardiography (TEE) is subject to the same types of artifacts encountered on two-dimensional TEE. However, when displayed in a 3D format, some of the artifacts appear more "realistic," whereas others are unique to image acquisition and postprocessing. Three-dimensional TEE is increasingly used in the setting of percutaneous catheter-based interventions and ablation procedures, and 3D artifacts caused by the metallic components of catheters and devices are particularly frequent. Knowledge of these artifacts is of paramount relevance to avoid misinterpretation of 3D images. Although artifacts and pitfalls on two-dimensional echocardiography are well described and classified, a systematic description of artifacts in 3D transesophageal echocardiographic images and how they affect 3D imaging is still absent. The aim of this review is to describe the most relevant artifacts on 3D TEE, with particular emphasis on those occurring during percutaneous interventions for structural heart disease and ablation procedures.

  16. Three-dimensional effects on airfoils

    NASA Technical Reports Server (NTRS)

    Chevallier, J. P.

    1983-01-01

    The effects of boundary layer flows along the walls of wind tunnels were studied to validate the transfer of two dimensional calculations to three dimensional transonic flowfield calculations. Results from trials in various wind tunnels were examind to determine the effects of the wall boundary flow on the control surfaces of an airfoil. Models sliding along a groove in the wall of a channel at sub- and transonic speeds were examined, with the finding that with either nonuniformities in the groove, or even if the channel walls are uniform, the lateral boundary layer can cause variations in the central flow region or alter the onset of shock at the transition point. Models for the effects in both turbulence and in the absence of turbulence are formulated, and it is noted that the characteristics of individual wind tunnels must be studied to quantify any existing three dimensional effects.

  17. Three-Dimensional Reconstruction of Helical Polymers

    PubMed Central

    Egelman, Edward H.

    2015-01-01

    The field of three-dimensional electron microscopy began more than 45 years ago with a reconstruction of a helical phage tail, and helical polymers continue to be important objects for three-dimensional reconstruction due to the centrality of helical protein and nucleoprotein polymers in all aspects of biology. We are now witnessing a fundamental revolution in this area, made possible by direct electron detectors, which has led to near-atomic resolution for a number of important helical structures. Most importantly, the possibility of achieving such resolution routinely for a vast number of helical samples is within our reach. One of the main problems in helical reconstruction, ambiguities in assigning the helical symmetry, is overcome when one reaches a resolution where secondary structure is clearly visible. However, obstacles still exist due to the intrinsic variability within many helical filaments. PMID:25912526

  18. Three dimensional fabrication at small size scales

    PubMed Central

    Leong, Timothy G.; Zarafshar, Aasiyeh M.; Gracias, David H.

    2010-01-01

    Despite the fact that we live in a three-dimensional (3D) world and macroscale engineering is 3D, conventional sub-mm scale engineering is inherently two-dimensional (2D). New fabrication and patterning strategies are needed to enable truly three-dimensionally-engineered structures at small size scales. Here, we review strategies that have been developed over the last two decades that seek to enable such millimeter to nanoscale 3D fabrication and patterning. A focus of this review is the strategy of self-assembly, specifically in a biologically inspired, more deterministic form known as self-folding. Self-folding methods can leverage the strengths of lithography to enable the construction of precisely patterned 3D structures and “smart” components. This self-assembling approach is compared with other 3D fabrication paradigms, and its advantages and disadvantages are discussed. PMID:20349446

  19. Three dimensional contact/impact methodology

    SciTech Connect

    Kulak, R.F.

    1987-01-01

    The simulation of three-dimensional interface mechanics between reactor components and structures during static contact or dynamic impact is necessary to realistically evaluate their structural integrity to off-normal loads. In our studies of postulated core energy release events, we have found that significant structure-structure interactions occur in some reactor vessel head closure designs and that fluid-structure interactions occur within the reactor vessel. Other examples in which three-dimensional interface mechanics play an important role are: (1) impact response of shipping casks containing spent fuel, (2) whipping pipe impact on reinforced concrete panels or pipe-to-pipe impact after a pipe break, (3) aircraft crash on secondary containment structures, (4) missiles generated by turbine failures or tornados, and (5) drops of heavy components due to lifting accidents. The above is a partial list of reactor safety problems that require adequate treatment of interface mechanics and are discussed in this paper.

  20. Three-dimensional bio-printing.

    PubMed

    Gu, Qi; Hao, Jie; Lu, YangJie; Wang, Liu; Wallace, Gordon G; Zhou, Qi

    2015-05-01

    Three-dimensional (3D) printing technology has been widely used in various manufacturing operations including automotive, defence and space industries. 3D printing has the advantages of personalization, flexibility and high resolution, and is therefore becoming increasingly visible in the high-tech fields. Three-dimensional bio-printing technology also holds promise for future use in medical applications. At present 3D bio-printing is mainly used for simulating and reconstructing some hard tissues or for preparing drug-delivery systems in the medical area. The fabrication of 3D structures with living cells and bioactive moieties spatially distributed throughout will be realisable. Fabrication of complex tissues and organs is still at the exploratory stage. This review summarize the development of 3D bio-printing and its potential in medical applications, as well as discussing the current challenges faced by 3D bio-printing. PMID:25921944

  1. Three-dimensional reconstruction of helical polymers.

    PubMed

    Egelman, Edward H

    2015-09-01

    The field of three-dimensional electron microscopy began more than 45years ago with a reconstruction of a helical phage tail, and helical polymers continue to be important objects for three-dimensional reconstruction due to the centrality of helical protein and nucleoprotein polymers in all aspects of biology. We are now witnessing a fundamental revolution in this area, made possible by direct electron detectors, which has led to near-atomic resolution for a number of important helical structures. Most importantly, the possibility of achieving such resolution routinely for a vast number of helical samples is within our reach. One of the main problems in helical reconstruction, ambiguities in assigning the helical symmetry, is overcome when one reaches a resolution where secondary structure is clearly visible. However, obstacles still exist due to the intrinsic variability within many helical filaments.

  2. Three-dimensional bio-printing.

    PubMed

    Gu, Qi; Hao, Jie; Lu, YangJie; Wang, Liu; Wallace, Gordon G; Zhou, Qi

    2015-05-01

    Three-dimensional (3D) printing technology has been widely used in various manufacturing operations including automotive, defence and space industries. 3D printing has the advantages of personalization, flexibility and high resolution, and is therefore becoming increasingly visible in the high-tech fields. Three-dimensional bio-printing technology also holds promise for future use in medical applications. At present 3D bio-printing is mainly used for simulating and reconstructing some hard tissues or for preparing drug-delivery systems in the medical area. The fabrication of 3D structures with living cells and bioactive moieties spatially distributed throughout will be realisable. Fabrication of complex tissues and organs is still at the exploratory stage. This review summarize the development of 3D bio-printing and its potential in medical applications, as well as discussing the current challenges faced by 3D bio-printing.

  3. Three-dimensional imaging modalities in endodontics

    PubMed Central

    Mao, Teresa

    2014-01-01

    Recent research in endodontics has highlighted the need for three-dimensional imaging in the clinical arena as well as in research. Three-dimensional imaging using computed tomography (CT) has been used in endodontics over the past decade. Three types of CT scans have been studied in endodontics, namely cone-beam CT, spiral CT, and peripheral quantitative CT. Contemporary endodontics places an emphasis on the use of cone-beam CT for an accurate diagnosis of parameters that cannot be visualized on a two-dimensional image. This review discusses the role of CT in endodontics, pertaining to its importance in the diagnosis of root canal anatomy, detection of peri-radicular lesions, diagnosis of trauma and resorption, presurgical assessment, and evaluation of the treatment outcome. PMID:25279337

  4. Three-dimensional Allan fault plane analysis

    SciTech Connect

    Hoffman, K.S.; Taylor, D.R.; Schnell, R.T.

    1994-12-31

    Allan fault-plane analysis is a useful tool for determining hydrocarbon migration paths and the location of possible traps. While initially developed for Gulf coast deltaic and interdeltaic environments, fault-plane analysis has been successfully applied in many other geologic settings. Where the geology involves several intersecting faults and greater complexity, many two-dimensional displays are required in the investigation and it becomes increasingly difficult to accurately visualize both fault relationships and migration routes. Three-dimensional geospatial fault and structure modeling using computer techniques, however, facilitates both visualization and understanding and extends fault-plane analysis into much more complex situations. When a model is viewed in three dimensions, the strata on both sides of a fault can be seen simultaneously while the true structural character of one or more fault surfaces is preserved. Three-dimensional analysis improves the speed and accuracy of the fault plane methodology.

  5. Simulation of complex three-dimensional flows

    NASA Technical Reports Server (NTRS)

    Diewert, G. S.; Rothmund, H. J.; Nakahashi, K.

    1985-01-01

    The concept of splitting is used extensively to simulate complex three dimensional flows on modern computer architectures. Used in all aspects, from initial grid generation to the determination of the final converged solution, splitting is used to enhance code vectorization, to permit solution driven grid adaption and grid enrichment, to permit the use of concurrent processing, and to enhance data flow through hierarchal memory systems. Three examples are used to illustrate these concepts to complex three dimensional flow fields: (1) interactive flow over a bump; (2) supersonic flow past a blunt based conical afterbody at incidence to a free stream and containing a centered propulsive jet; and (3) supersonic flow past a sharp leading edge delta wing at incidence to the free stream.

  6. Three-dimensional Lorentz-violating action

    NASA Astrophysics Data System (ADS)

    Nascimento, J. R.; Petrov, A. Yu.; Wotzasek, C.; Zarro, C. A. D.

    2014-03-01

    We demonstrate the generation of the three-dimensional Chern-Simons-like Lorentz-breaking "mixed" quadratic action via an appropriate Lorentz-breaking coupling of vector and scalar fields to the spinor field and study some features of the scalar QED with such a term. We show that the same term emerges through a nonperturbative method, namely the Julia-Toulouse approach of condensation of charges and defects.

  7. Three-dimensional ballistocardiography in weightlessness

    NASA Technical Reports Server (NTRS)

    Scano, A.

    1981-01-01

    An experiment is described the aim of which is to record a three dimensional ballistocardiogram under the condition of weightlessness and to compare it with tracings recorded on the same subject on the ground as a means of clarifying the meaning of ballistocardiogram waves in different physiological and perphaps pathological conditions. Another purpose is to investigate cardiovascular and possibly fluid adaptations to weightlessness from data collected almost simultaneously on the same subjects during the other cardiovascular during the other cardiovascular and metabolic experiments.

  8. Stress tensor correlators in three dimensional gravity

    NASA Astrophysics Data System (ADS)

    Bagchi, Arjun; Grumiller, Daniel; Merbis, Wout

    2016-03-01

    We calculate holographically arbitrary n -point correlators of the boundary stress tensor in three-dimensional Einstein gravity with negative or vanishing cosmological constant. We provide explicit expressions up to 5-point (connected) correlators and show consistency with the Galilean conformal field theory Ward identities and recursion relations of correlators, which we derive. This provides a novel check of flat space holography in three dimensions.

  9. Three-Dimensional Dispaly Of Document Set

    DOEpatents

    Lantrip, David B.; Pennock, Kelly A.; Pottier, Marc C.; Schur, Anne; Thomas, James J.; Wise, James A.

    2003-06-24

    A method for spatializing text content for enhanced visual browsing and analysis. The invention is applied to large text document corpora such as digital libraries, regulations and procedures, archived reports, and the like. The text content from these sources may be transformed to a spatial representation that preserves informational characteristics from the documents. The three-dimensional representation may then be visually browsed and analyzed in ways that avoid language processing and that reduce the analysts' effort.

  10. Three-dimensional display of document set

    DOEpatents

    Lantrip, David B [Oxnard, CA; Pennock, Kelly A [Richland, WA; Pottier, Marc C [Richland, WA; Schur, Anne [Richland, WA; Thomas, James J [Richland, WA; Wise, James A [Richland, WA

    2001-10-02

    A method for spatializing text content for enhanced visual browsing and analysis. The invention is applied to large text document corpora such as digital libraries, regulations and procedures, archived reports, and the like. The text content from these sources may be transformed to a spatial representation that preserves informational characteristics from the documents. The three-dimensional representation may then be visually browsed and analyzed in ways that avoid language processing and that reduce the analysts' effort.

  11. Three-dimensional display of document set

    DOEpatents

    Lantrip, David B.; Pennock, Kelly A.; Pottier, Marc C.; Schur, Anne; Thomas, James J.; Wise, James A.

    2006-09-26

    A method for spatializing text content for enhanced visual browsing and analysis. The invention is applied to large text document corpora such as digital libraries, regulations and procedures, archived reports, and the like. The text content from these sources may e transformed to a spatial representation that preserves informational characteristics from the documents. The three-dimensional representation may then be visually browsed and analyzed in ways that avoid language processing and that reduce the analysts' effort.

  12. Three-dimensional display of document set

    DOEpatents

    Lantrip, David B.; Pennock, Kelly A.; Pottier, Marc C.; Schur, Anne; Thomas, James J.; Wise, James A.; York, Jeremy

    2009-06-30

    A method for spatializing text content for enhanced visual browsing and analysis. The invention is applied to large text document corpora such as digital libraries, regulations and procedures, archived reports, and the like. The text content from these sources may be transformed to a spatial representation that preserves informational characteristics from the documents. The three-dimensional representation may then be visually browsed and analyzed in ways that avoid language processing and that reduce the analysts' effort.

  13. Three-Dimensional Printing in Orthopedic Surgery.

    PubMed

    Eltorai, Adam E M; Nguyen, Eric; Daniels, Alan H

    2015-11-01

    Three-dimensional (3D) printing is emerging as a clinically promising technology for rapid prototyping of surgically implantable products. With this commercially available technology, computed tomography or magnetic resonance images can be used to create graspable objects from 3D reconstructed images. Models can enhance patients' understanding of their pathology and surgeon preoperative planning. Customized implants and casts can be made to match an individual's anatomy. This review outlines 3D printing, its current applications in orthopedics, and promising future directions.

  14. Method and apparatus for three dimensional braiding

    NASA Technical Reports Server (NTRS)

    Farley, Gary L. (Inventor)

    1997-01-01

    A machine for three-dimensional braiding of fibers is provided in which carrier members travel on a curved, segmented and movable braiding surface. The carrier members are capable of independent, self-propelled motion along the braiding surface. Carrier member position on the braiding surface is controlled and monitored by computer. Also disclosed is a yarn take-up device capable of maintaining tension in the braiding fiber.

  15. Method and apparatus for three dimensional braiding

    NASA Technical Reports Server (NTRS)

    Farley, Gary L. (Inventor)

    1995-01-01

    A machine for three-dimensional braiding of fibers is provided in which carrier members travel on a curved, segmented and movable braiding surface. The carrier members are capable of independent, self-propelled motion along the braiding surface. Carrier member position on the braiding surface is controlled and monitored by computer. Also disclosed is a yarn take-up device capable of maintaining tension in the braiding fiber.

  16. Mineralized three-dimensional bone constructs

    NASA Technical Reports Server (NTRS)

    Clarke, Mark S. F. (Inventor); Sundaresan, Alamelu (Inventor); Pellis, Neal R. (Inventor)

    2011-01-01

    The present disclosure provides ex vivo-derived mineralized three-dimensional bone constructs. The bone constructs are obtained by culturing osteoblasts and osteoclast precursors under randomized gravity vector conditions. Preferably, the randomized gravity vector conditions are obtained using a low shear stress rotating bioreactor, such as a High Aspect Ratio Vessel (HARV) culture system. The bone constructs of the disclosure have utility in physiological studies of bone formation and bone function, in drug discovery, and in orthopedics.

  17. Mineralized Three-Dimensional Bone Constructs

    NASA Technical Reports Server (NTRS)

    Clarke, Mark S. F. (Inventor); Sundaresan, Alamelu (Inventor); Pellis, Neal R. (Inventor)

    2013-01-01

    The present disclosure provides ex vivo-derived mineralized three-dimensional bone constructs. The bone constructs are obtained by culturing osteoblasts and osteoclast precursors under randomized gravity vector conditions. Preferably, the randomized gravity vector conditions are obtained using a low shear stress rotating bioreactor, such as a High Aspect Ratio Vessel (HARV) culture system. The bone constructs of the disclosure have utility in physiological studies of bone formation and bone function, in drug discovery, and in orthopedics.

  18. Three-dimensional motor schema based navigation

    NASA Technical Reports Server (NTRS)

    Arkin, Ronald C.

    1989-01-01

    Reactive schema-based navigation is possible in space domains by extending the methods developed for ground-based navigation found within the Autonomous Robot Architecture (AuRA). Reformulation of two dimensional motor schemas for three dimensional applications is a straightforward process. The manifold advantages of schema-based control persist, including modular development, amenability to distributed processing, and responsiveness to environmental sensing. Simulation results show the feasibility of this methodology for space docking operations in a cluttered work area.

  19. Three-dimensional adjustment of trilateration data

    NASA Technical Reports Server (NTRS)

    Sung, L.-Y.; Jackson, D. D.

    1985-01-01

    The three-dimensional locations of the monuments in the USGS Hollister trilateration network were adjusted to fit line length observations observed in 1977, using a Bayesian approach, and incorporating prior elevation estimates as data in the adjustment procedure. No significant discrepancies in the measured line lengths were found, but significant elevation adjustments (up to 1.85 m) were needed to fit the length data.

  20. Three-dimensional photogrammetry for laboratory applications

    NASA Astrophysics Data System (ADS)

    Alem, Nabih M.

    1994-12-01

    The direct linear transformation (DLT) is a method that simplifies measurements of the three-dimensional coordinates of a point target in the laboratory using photographic two-dimensional imagery. This report describes a procedure to implement the DLT equations and gives the Fortran code of computer programs for the DLT calibration of multicamera system and 3-D reconstruction of a single point from several images.

  1. Analysis of real-time vibration data

    USGS Publications Warehouse

    Safak, E.

    2005-01-01

    In recent years, a few structures have been instrumented to provide continuous vibration data in real time, recording not only large-amplitude motions generated by extreme loads, but also small-amplitude motions generated by ambient loads. The main objective in continuous recording is to track any changes in structural characteristics, and to detect damage after an extreme event, such as an earthquake or explosion. The Fourier-based spectral analysis methods have been the primary tool to analyze vibration data from structures. In general, such methods do not work well for real-time data, because real-time data are mainly composed of ambient vibrations with very low amplitudes and signal-to-noise ratios. The long duration, linearity, and the stationarity of ambient data, however, allow us to utilize statistical signal processing tools, which can compensate for the adverse effects of low amplitudes and high noise. The analysis of real-time data requires tools and techniques that can be applied in real-time; i.e., data are processed and analyzed while being acquired. This paper presents some of the basic tools and techniques for processing and analyzing real-time vibration data. The topics discussed include utilization of running time windows, tracking mean and mean-square values, filtering, system identification, and damage detection.

  2. Application of Fourier transform and autocorrelation to cluster identification in the three-dimensional atom probe.

    PubMed

    Vurpillot, F; De Geuser, F; Da Costa, G; Blavette, D

    2004-12-01

    Because of the increasing number of collected atoms (up to millions) in the three-dimensional atom probe, derivation of chemical or structural information from the direct observation of three-dimensional images is becoming more and more difficult. New data analysis tools are thus required. Application of a discrete Fourier transform algorithm to three-dimensional atom probe datasets provides information that is not easily accessible in real space. Derivation of mean particle size from Fourier intensities or from three-dimensional autocorrelation is an example. These powerful methods can be used to detect and image nano-segregations. Using three-dimensional 'bright-field' imaging, single nano-segregations were isolated from the surrounding matrix of an iron-copper alloy. Measurement of the inner concentration within clusters is, therefore, straightforward. Theoretical aspects related to filtering in reciprocal space are developed.

  3. Real-time smart fluorescence sensor platform

    NASA Astrophysics Data System (ADS)

    Dickens, Jason E.; Vaughn, Mike S.; Taylor, Mervin; Ponstingl, Mike

    2011-06-01

    A novel compact LED array based light induced fluorescence (LIF) sensor has been developed for real-time in-line monitoring of intrinsic fluorophores in the solid and liquid state. The sensor is essential for on-the-spot, routine, and cost effective real-time analysis. The sensor is designed to provide real-time emission response along with various smart sensing parameters to ensure real-time measurement quality that is required for regulated GMP process monitoring applications. This work describes a LIF sensor tailored for solid-phase fluorometry. Fundamental figures of merit, excitation overexposure and smart sensing features required for modern process monitoring and control are discussed within the context of pharmaceutical solid-phase manufacturing and similar applications.

  4. Three-Dimensional Audio Client Library

    NASA Technical Reports Server (NTRS)

    Rizzi, Stephen A.

    2005-01-01

    The Three-Dimensional Audio Client Library (3DAudio library) is a group of software routines written to facilitate development of both stand-alone (audio only) and immersive virtual-reality application programs that utilize three-dimensional audio displays. The library is intended to enable the development of three-dimensional audio client application programs by use of a code base common to multiple audio server computers. The 3DAudio library calls vendor-specific audio client libraries and currently supports the AuSIM Gold-Server and Lake Huron audio servers. 3DAudio library routines contain common functions for (1) initiation and termination of a client/audio server session, (2) configuration-file input, (3) positioning functions, (4) coordinate transformations, (5) audio transport functions, (6) rendering functions, (7) debugging functions, and (8) event-list-sequencing functions. The 3DAudio software is written in the C++ programming language and currently operates under the Linux, IRIX, and Windows operating systems.

  5. Three-dimensional Chiral Plasmonic Oligomers

    NASA Astrophysics Data System (ADS)

    Hentschel, Mario

    2013-03-01

    We demonstrate chiral optical response in stacked arrangements of plasmonic nanostructures. We show that three-dimensional arrangements of plasmonic ``meta-atoms'' only exhibit a chiral optical response if similar plasmonic ``atoms'' are arranged in a handed fashion as we require resonant plasmonic coupling. Moreover, we demonstrate that such particle groupings, similarly to molecular systems, possess the capability to encode their three-dimensional arrangement in unique and well-modulated spectra, making them ideal candidates for a three-dimensional chiral plasmon ruler. Furthermore, we discuss the onset of a broadband chiral optical response in the wavelength regime between 700 nm and 3500 nm upon charge transfer between the nanoparticles. We show in experiment and simulation that this response is due to the ohmic contact between adjacent particles which causes a strong red-shift of the fundamental mode. The geometrical shape of the resulting fused particles allows for efficient excitation of higher order modes. Calculated spectra and field distributions confirm our interpretation and show a number of interacting plasmonic modes. Finally, we will discuss plasmonic diastereomers which consist of multiple chiral centers. We find that the chiral optical response of the composite molecules can be traced back to the properties of the constituting building blocks. We demonstrate that the optical response of complex chiral plasmonic systems can be decomposed and understood in terms of fundamental building blocks, offering simple and straightforward design rules for future applications such as chiral optical elements and enantiomer sensors.

  6. Reconfigurable, braced, three-dimensional DNA nanostructures

    NASA Astrophysics Data System (ADS)

    Goodman, Russell P.; Heilemann, Mike; Doose, Sören; Erben, Christoph M.; Kapanidis, Achillefs N.; Turberfield, Andrew J.

    2008-02-01

    DNA nanotechnology makes use of the exquisite self-recognition of DNA in order to build on a molecular scale. Although static structures may find applications in structural biology and computer science, many applications in nanomedicine and nanorobotics require the additional capacity for controlled three-dimensional movement. DNA architectures can span three dimensions and DNA devices are capable of movement, but active control of well-defined three-dimensional structures has not been achieved. We demonstrate the operation of reconfigurable DNA tetrahedra whose shapes change precisely and reversibly in response to specific molecular signals. Shape changes are confirmed by gel electrophoresis and by bulk and single-molecule Förster resonance energy transfer measurements. DNA tetrahedra are natural building blocks for three-dimensional construction; they may be synthesized rapidly with high yield of a single stereoisomer, and their triangulated architecture conveys structural stability. The introduction of shape-changing structural modules opens new avenues for the manipulation of matter on the nanometre scale.

  7. Multiparallel Three-Dimensional Optical Microscopy

    NASA Technical Reports Server (NTRS)

    Nguyen, Lam K.; Price, Jeffrey H.; Kellner, Albert L.; Bravo-Zanoquera, Miguel

    2010-01-01

    Multiparallel three-dimensional optical microscopy is a method of forming an approximate three-dimensional image of a microscope sample as a collection of images from different depths through the sample. The imaging apparatus includes a single microscope plus an assembly of beam splitters and mirrors that divide the output of the microscope into multiple channels. An imaging array of photodetectors in each channel is located at a different distance along the optical path from the microscope, corresponding to a focal plane at a different depth within the sample. The optical path leading to each photodetector array also includes lenses to compensate for the variation of magnification with distance so that the images ultimately formed on all the photodetector arrays are of the same magnification. The use of optical components common to multiple channels in a simple geometry makes it possible to obtain high light-transmission efficiency with an optically and mechanically simple assembly. In addition, because images can be read out simultaneously from all the photodetector arrays, the apparatus can support three-dimensional imaging at a high scanning rate.

  8. Three-dimensional printing of the retina

    PubMed Central

    Lorber, Barbara; Hsiao, Wen-Kai; Martin, Keith R.

    2016-01-01

    Purpose of review Biological three-dimensional printing has received a lot of media attention over recent years with advances made in printing cellular structures, including skin and heart tissue for transplantation. Although limitations exist in creating functioning organs with this method, the hope has been raised that creating a functional retina to cure blindness is within reach. The present review provides an update on the advances made toward this goal. Recent findings It has recently been shown that two types of retinal cells, retinal ganglion cells and glial cells, can be successfully printed using a piezoelectric inkjet printer. Importantly, the cells remained viable and did not change certain phenotypic features as a result of the printing process. In addition, recent advances in the creation of complex and viable three-dimensional cellular structures have been made. Summary Some first promising steps toward the creation of a functional retina have been taken. It now needs to be investigated whether recent findings can be extended to other cells of the retina, including those derived from human tissue, and if a complex and viable retinal structure can be created through three-dimensional printing. PMID:27045545

  9. Three-dimensional deformation of orthodontic brackets

    PubMed Central

    Melenka, Garrett W; Nobes, David S; Major, Paul W

    2013-01-01

    Braces are used by orthodontists to correct the misalignment of teeth in the mouth. Archwire rotation is a particular procedure used to correct tooth inclination. Wire rotation can result in deformation to the orthodontic brackets, and an orthodontic torque simulator has been designed to examine this wire–bracket interaction. An optical technique has been employed to measure the deformation due to size and geometric constraints of the orthodontic brackets. Images of orthodontic brackets are collected using a stereo microscope and two charge-coupled device cameras, and deformation of orthodontic brackets is measured using a three-dimensional digital image correlation technique. The three-dimensional deformation of orthodontic brackets will be evaluated. The repeatability of the three-dimensional digital image correlation measurement method was evaluated by performing 30 archwire rotation tests using the same bracket and archwire. Finally, five Damon 3MX and five In-Ovation R self-ligating brackets will be compared using this technique to demonstrate the effect of archwire rotation on bracket design. PMID:23762201

  10. The LAA real-time benchmarks

    SciTech Connect

    Block, R.K.; Krischer, W.; Lone, S.

    1989-04-01

    In the context of the LAA detector development program a subgroup Real Time Data Processing has tackled the problem of intelligent triggering. The main goal of this group is to show how fast digital devices, implemented as custom-made or commercial processors, can execute some basic algorithms, and how they can be embedded in the data flow between detector readout components and fully programmable commercial processors, which are expected to be the final data processing filter in real time.

  11. Real-time scheduling using minimum search

    NASA Technical Reports Server (NTRS)

    Tadepalli, Prasad; Joshi, Varad

    1992-01-01

    In this paper we consider a simple model of real-time scheduling. We present a real-time scheduling system called RTS which is based on Korf's Minimin algorithm. Experimental results show that the schedule quality initially improves with the amount of look-ahead search and tapers off quickly. So it sppears that reasonably good schedules can be produced with a relatively shallow search.

  12. Processing PCM Data in Real Time

    NASA Technical Reports Server (NTRS)

    Wissink, T. L.

    1982-01-01

    Novel hardware configuration makes it possible for Space Shuttle launch processing system to monitor pulse-code-modulated data in real time. Using two microprogramable "option planes," incoming PCM data are monitored for changes at rate of one frame of data (80 16-bit words) every 10 milliseconds. Real-time PCM processor utilizes CPU in mini-computer and CPU's in two option planes.

  13. Interferometer real time control development for SIM

    NASA Astrophysics Data System (ADS)

    Bell, Charles E.

    2003-02-01

    Real Time Control (RTC) for the Space Interferometry Mission will build on the real time core interferometer control technology under development at JPL since the mid 1990s, with heritage from the ground based MKII and Palomar Testbed Interferometer projects developed in the late '80s and early '90s. The core software and electronics technology for SIM interferometer real time control is successfully operating on several SIM technology demonstration testbeds, including the Real-time Interferometer Control System Testbed, System Testbed-3, and the Microarcsecond Metrology testbed. This paper provides an overview of the architecture, design, integration, and test of the SIM flight interferometer real time control to meet challenging flight system requirements for the high processor throughput, low-latency interconnect, and precise synchronization to support microarcsecond-level astrometric measurements for greater than five years at 1 AU in Earth-trailing orbit. The electronics and software architecture of the interferometer real time control core and its adaptation to a flight design concept are described. Control loops for pointing and pathlength control within each of four flight interferometers and for coordination of control and data across interferometers are illustrated. The nature of onboard data processing to fit average downlink rates while retaining post-processed astrometric measurement precision and accuracy is also addressed. Interferometer flight software will be developed using a software simulation environment incorporating models of the metrology and starlight sensors and actuators to close the real time control loops. RTC flight software and instrument flight electronics will in turn be integrated utilizing the same simulation architecture for metrology and starlight component models to close real time control loops and verify RTC functionality and performance prior to delivery to flight interferometer system integration at Lockheed Martin

  14. Three-dimensional imaging characteristics and depth resolution in digital holographic three-dimensional imaging spectrometry

    NASA Astrophysics Data System (ADS)

    Obara, Masaki; Yoshimori, Kyu

    2015-07-01

    A four-dimensional impulse response function for the digital holographic three-dimensional imaging spectrometry has been fully derived in closed form. Due to its factorizing nature of the mathematical expression of four-dimensional impulse response function, three-dimensional spatial part of impulse response function directly corresponds to threedimensional point spread function of in-line digital holography with rectangular aperture. Based on these mathematical results, this paper focuses on the investigation of spectral resolution and three-dimensional spatial resolution in digital holographic three-dimensional imaging spectrometry and digital holography. We found that the theoretical prediction agree well with the experimental results. This work suggests a new criterion and estimate method regarding threedimensional spatial resolution of in-line digital holography.

  15. Advanced Visualization of Experimental Data in Real Time Using LiveView3D

    NASA Technical Reports Server (NTRS)

    Schwartz, Richard J.; Fleming, Gary A.

    2006-01-01

    LiveView3D is a software application that imports and displays a variety of wind tunnel derived data in an interactive virtual environment in real time. LiveView3D combines the use of streaming video fed into a three-dimensional virtual representation of the test configuration with networked communications to the test facility Data Acquisition System (DAS). This unified approach to real time data visualization provides a unique opportunity to comprehend very large sets of diverse forms of data in a real time situation, as well as in post-test analysis. This paper describes how LiveView3D has been implemented to visualize diverse forms of aerodynamic data gathered during wind tunnel experiments, most notably at the NASA Langley Research Center Unitary Plan Wind Tunnel (UPWT). Planned future developments of the LiveView3D system are also addressed.

  16. Real-time aerodynamic heating and surface temperature calculations for hypersonic flight simulation

    NASA Technical Reports Server (NTRS)

    Quinn, Robert D.; Gong, Leslie

    1990-01-01

    A real-time heating algorithm was derived and installed on the Ames Research Center Dryden Flight Research Facility real-time flight simulator. This program can calculate two- and three-dimensional stagnation point surface heating rates and surface temperatures. The two-dimensional calculations can be made with or without leading-edge sweep. In addition, upper and lower surface heating rates and surface temperatures for flat plates, wedges, and cones can be calculated. Laminar or turbulent heating can be calculated, with boundary-layer transition made a function of free-stream Reynolds number and free-stream Mach number. Real-time heating rates and surface temperatures calculated for a generic hypersonic vehicle are presented and compared with more exact values computed by a batch aeroheating program. As these comparisons show, the heating algorithm used on the flight simulator calculates surface heating rates and temperatures well within the accuracy required to evaluate flight profiles for acceptable heating trajectories.

  17. Improved process control through real-time measurement of mineral content

    SciTech Connect

    Turler, Daniel; Karaca, Murat; Davis, William B.; Giauque, Robert D.; Hopkins, Deborah

    2001-11-02

    In a highly collaborative research and development project with mining and university partners, sensors and data-analysis tools are being developed for rock-mass characterization and real-time measurement of mineral content. Determining mineralogy prior to mucking in an open-pit mine is important for routing the material to the appropriate processing stream. A possible alternative to lab assay of dust and cuttings obtained from drill holes is continuous on-line sampling and real-time x-ray fluorescence (XRF) spectroscopy. Results presented demonstrate that statistical analyses combined with XRF data can be employed to identify minerals and, possibly, different rock types. The objective is to create a detailed three-dimensional mineralogical map in real time that would improve downstream process efficiency.

  18. FPGA-based real-time anisotropic diffusion filtering of 3D ultrasound images

    NASA Astrophysics Data System (ADS)

    Castro-Pareja, Carlos R.; Dandekar, Omkar S.; Shekhar, Raj

    2005-02-01

    Three-dimensional ultrasonic imaging, especially the emerging real-time version of it, is particularly valuable in medical applications such as echocardiography, obstetrics and surgical navigation. A known problem with ultrasound images is their high level of speckle noise. Anisotropic diffusion filtering has been shown to be effective in enhancing the visual quality of 3D ultrasound images and as preprocessing prior to advanced image processing. However, due to its arithmetic complexity and the sheer size of 3D ultrasound images, it is not possible to perform online, real-time anisotropic diffusion filtering using standard software implementations. We present an FPGA-based architecture that allows performing anisotropic diffusion filtering of 3D images at acquisition rates, thus enabling the use of this filtering technique in real-time applications, such as visualization, registration and volume rendering.

  19. Recent developments in three-dimensional numerical estuarine models

    USGS Publications Warehouse

    Cheng, Ralph T.; Smith, Peter E.; Casulli, Vincenzo

    1993-01-01

    For a fixed cost, computing power increases 5 to 10 times every five years. The readily available computing resources have inspired new modal formulations and innovative model applications. Significant progress has been advanced in three-dimensional numerical estuarine modeling within the past three or four years. This paper attempts to review and summarize properties of new 3-D estuarine hydrodynamic models. The emphasis of the review is placed on the formulation, numerical methods. The emphasis of the review is placed on the formulation, numerical methods, spatial and temporal resolution, computational efficiency, and turbulence closure of new models. Recent research has provided guidelines for the proper use of 3-D models involving in the σ-transformation. Other models resort to a fixed level discretization in the vertical. The semi-implicit treatment in time-stepping models appears to have gained momentum. Future research in three-dimensional numerical modeling remains to be on computational efficiency and turbulent closure.

  20. In-Situ Three-Dimensional Shape Rendering from Strain Values Obtained Through Optical Fiber Sensors

    NASA Technical Reports Server (NTRS)

    Chan, Hon Man (Inventor); Parker, Jr., Allen R. (Inventor)

    2015-01-01

    A method and system for rendering the shape of a multi-core optical fiber or multi-fiber bundle in three-dimensional space in real time based on measured fiber strain data. Three optical fiber cores arc arranged in parallel at 120.degree. intervals about a central axis. A series of longitudinally co-located strain sensor triplets, typically fiber Bragg gratings, are positioned along the length of each fiber at known intervals. A tunable laser interrogates the sensors to detect strain on the fiber cores. Software determines the strain magnitude (.DELTA.L/L) for each fiber at a given triplet, but then applies beam theory to calculate curvature, beading angle and torsion of the fiber bundle, and from there it determines the shape of the fiber in s Cartesian coordinate system by solving a series of ordinary differential equations expanded from the Frenet-Serrat equations. This approach eliminates the need for computationally time-intensive curve-tilting and allows the three-dimensional shape of the optical fiber assembly to be displayed in real-time.

  1. A regional adaptive and assimilative three-dimensional ionospheric model

    NASA Astrophysics Data System (ADS)

    Sabbagh, Dario; Scotto, Carlo; Sgrigna, Vittorio

    2016-03-01

    A regional adaptive and assimilative three-dimensional (3D) ionospheric model is proposed. It is able to ingest real-time data from different ionosondes, providing the ionospheric bottomside plasma frequency fp over the Italian area. The model is constructed on the basis of empirical values for a set of ionospheric parameters Pi[base] over the considered region, some of which have an assigned variation ΔPi. The values for the ionospheric parameters actually observed at a given time at a given site will thus be Pi = Pi[base] + ΔPi. These Pi values are used as input for an electron density N(h) profiler. The latter is derived from the Advanced Ionospheric Profiler (AIP), which is software used by Autoscala as part of the process of automatic inversion of ionogram traces. The 3D model ingests ionosonde data by minimizing the root-mean-square deviation between the observed and modeled values of fp(h) profiles obtained from the associated N(h) values at the points where observations are available. The ΔPi values are obtained from this minimization procedure. The 3D model is tested using data collected at the ionospheric stations of Rome (41.8N, 12.5E) and Gibilmanna (37.9N, 14.0E), and then comparing the results against data from the ionospheric station of San Vito dei Normanni (40.6N, 18.0E). The software developed is able to produce maps of the critical frequencies foF2 and foF1, and of fp at a fixed altitude, with transverse and longitudinal cross-sections of the bottomside ionosphere in a color scale. fp(h) and associated simulated ordinary ionogram traces can easily be produced for any geographic location within the Italian region. fp values within the volume in question can also be provided.

  2. REAL TIME SYSTEM OPERATIONS 2006-2007

    SciTech Connect

    Eto, Joseph H.; Parashar, Manu; Lewis, Nancy Jo

    2008-08-15

    The Real Time System Operations (RTSO) 2006-2007 project focused on two parallel technical tasks: (1) Real-Time Applications of Phasors for Monitoring, Alarming and Control; and (2) Real-Time Voltage Security Assessment (RTVSA) Prototype Tool. The overall goal of the phasor applications project was to accelerate adoption and foster greater use of new, more accurate, time-synchronized phasor measurements by conducting research and prototyping applications on California ISO's phasor platform - Real-Time Dynamics Monitoring System (RTDMS) -- that provide previously unavailable information on the dynamic stability of the grid. Feasibility assessment studies were conducted on potential application of this technology for small-signal stability monitoring, validating/improving existing stability nomograms, conducting frequency response analysis, and obtaining real-time sensitivity information on key metrics to assess grid stress. Based on study findings, prototype applications for real-time visualization and alarming, small-signal stability monitoring, measurement based sensitivity analysis and frequency response assessment were developed, factory- and field-tested at the California ISO and at BPA. The goal of the RTVSA project was to provide California ISO with a prototype voltage security assessment tool that runs in real time within California ISO?s new reliability and congestion management system. CERTS conducted a technical assessment of appropriate algorithms, developed a prototype incorporating state-of-art algorithms (such as the continuation power flow, direct method, boundary orbiting method, and hyperplanes) into a framework most suitable for an operations environment. Based on study findings, a functional specification was prepared, which the California ISO has since used to procure a production-quality tool that is now a part of a suite of advanced computational tools that is used by California ISO for reliability and congestion management.

  3. Three-dimensional discrete ordinates reactor assembly calculations on GPUs

    SciTech Connect

    Evans, Thomas M; Joubert, Wayne; Hamilton, Steven P; Johnson, Seth R; Turner, John A; Davidson, Gregory G; Pandya, Tara M

    2015-01-01

    In this paper we describe and demonstrate a discrete ordinates sweep algorithm on GPUs. This sweep algorithm is nested within a multilevel comunication-based decomposition based on energy. We demonstrated the effectiveness of this algorithm on detailed three-dimensional critical experiments and PWR lattice problems. For these problems we show improvement factors of 4 6 over conventional communication-based, CPU-only sweeps. These sweep kernel speedups resulted in a factor of 2 total time-to-solution improvement.

  4. A real-time volumetric visualization system for electrical impedance tomography.

    PubMed

    Briggs, N M; Avis, N J; Kleinermann, F

    2000-02-01

    Three dimensional (3D) electrical impedance tomography (EIT) presents many additional challenges over and above those associated with two dimensional EIT systems. With present two dimensional (2D) systems, tomographs can be reconstructed and displayed on a PC with a standard computer monitor. In addition, using appropriate data acquisition hardware and simple image reconstruction algorithms, it is possible to collect, reconstruct and display volumetric EIT images in real time using parallel processing architectures. The advantages of this 'real-time' capability are many and include the ability to immediately assess the correct functioning of the system and the ability to track patient events and the effect of procedures in real time. Whilst 3D EIT boundary datasets can be collected in real time, their real-time image reconstruction and display presents some computational challenges. This explains why, to date, no real-time solutions have been presented. In addition the use of a standard computer monitor to display 3D volumes is unsatisfactory since not all depth cues are preserved when using this type of 2D display device. We present a system which is capable of displaying 3D EIT datasets in real time and allows interactive modification of the user's viewpoint. This allows the user to fly around (and through) the EIT volumetric dataset.

  5. Augmented reality three-dimensional display with light field fusion.

    PubMed

    Xie, Songlin; Wang, Peng; Sang, Xinzhu; Li, Chengyu

    2016-05-30

    A video see-through augmented reality three-dimensional display method is presented. The system that is used for dense viewpoint augmented reality presentation fuses the light fields of the real scene and the virtual model naturally. Inherently benefiting from the rich information of the light field, depth sense and occlusion can be handled under no priori depth information of the real scene. A series of processes are proposed to optimize the augmented reality performance. Experimental results show that the reconstructed fused 3D light field on the autostereoscopic display is well presented. The virtual model is naturally integrated into the real scene with a consistence between binocular parallax and monocular depth cues. PMID:27410076

  6. Augmented reality three-dimensional display with light field fusion.

    PubMed

    Xie, Songlin; Wang, Peng; Sang, Xinzhu; Li, Chengyu

    2016-05-30

    A video see-through augmented reality three-dimensional display method is presented. The system that is used for dense viewpoint augmented reality presentation fuses the light fields of the real scene and the virtual model naturally. Inherently benefiting from the rich information of the light field, depth sense and occlusion can be handled under no priori depth information of the real scene. A series of processes are proposed to optimize the augmented reality performance. Experimental results show that the reconstructed fused 3D light field on the autostereoscopic display is well presented. The virtual model is naturally integrated into the real scene with a consistence between binocular parallax and monocular depth cues.

  7. Real-time, high frequency QRS electrocardiograph

    NASA Technical Reports Server (NTRS)

    Schlegel, Todd T. (Inventor); DePalma, Jude L. (Inventor); Moradi, Saeed (Inventor)

    2006-01-01

    Real time cardiac electrical data are received from a patient, manipulated to determine various useful aspects of the ECG signal, and displayed in real time in a useful form on a computer screen or monitor. The monitor displays the high frequency data from the QRS complex in units of microvolts, juxtaposed with a display of conventional ECG data in units of millivolts or microvolts. The high frequency data are analyzed for their root mean square (RMS) voltage values and the discrete RMS values and related parameters are displayed in real time. The high frequency data from the QRS complex are analyzed with imbedded algorithms to determine the presence or absence of reduced amplitude zones, referred to herein as RAZs. RAZs are displayed as go, no-go signals on the computer monitor. The RMS and related values of the high frequency components are displayed as time varying signals, and the presence or absence of RAZs may be similarly displayed over time.

  8. Three-dimensional non-linear instability of spontaneous fast magnetic reconnection

    NASA Astrophysics Data System (ADS)

    Shimizu, T.; Kondoh, K.; Ugai, M.

    2009-05-01

    Three-dimensional instability of spontaneous fast magnetic reconnection is studied using MHD (magnetohydro- dynamic) simulation. Previous two-dimensional MHD studies have demonstrated that, if a current-driven anomalous resistivity is assumed, two-dimensional fast magnetic reconnection occurs and two-dimensional largescale magnetic loops, i.e., plasmoids, are ejected from the reconnection region. In most two-dimensional MHD studies, the structure of the current sheet is initially one-dimensinal. On the other hand, in recent space plasma observations, fully three-dimensional magnetic loops frequently appear even in the almost one-dimensional current sheet. This suggests that the classical two-dimensional fast magnetic reconnection may be unstable to any three-dimensional perturbation, resulting in three-dimensional fast magnetic reconnection. In this paper, we show that a three-dimensional resistive perturbation destabilizes two-dimensional fast magnetic reconnection and results in three-dimensional fast magnetic reconnection. The resulting three-dimensional fast reconnection repeatedly ejects three-dimensional magnetic loops downstream. The obtained numerical results are similar to the pulsating downflows observed in solar flares. According to the Fourier analysis of the ejected magnetic loops, the time evolution of this three-dimensional instability is fully non-linear.

  9. Real-time microscopic phase-shifting profilometry.

    PubMed

    Van der Jeught, Sam; Soons, Joris A M; Dirckx, Joris J J

    2015-05-20

    A real-time microscopic profilometry system based on digital fringe projection and parallel programming has been developed and experimentally tested. Structured light patterns are projected onto an object through one pathway of a stereoscopic operation microscope. The patterns are deformed by the shape of the object and are then recorded with a high-speed CCD camera placed in the other pathway of the microscope. As the optical pathways of both arms are separated and reach the same object point at a relative angle, the recorded patterns allow the full-field object height variations to be calculated and the three-dimensional shape to be reconstructed by employing standard triangulation techniques. Applying proper hardware triggering, the projector-camera system is synchronized to capture up to 120 unique deformed line patterns per second. Using standard four-step phase-shifting profilometry techniques and applying graphics processing unit programming for fast phase wrapping, scaling, and visualization, we demonstrate the capability of the proposed system to generate 30 microscopic height maps per second. This allows the qualitative depth perception of the stereomicroscope operator to be enhanced by live quantitative height measurements with depth resolutions in the micrometer range. PMID:26192534

  10. Characterization of real-time computers

    NASA Technical Reports Server (NTRS)

    Shin, K. G.; Krishna, C. M.

    1984-01-01

    A real-time system consists of a computer controller and controlled processes. Despite the synergistic relationship between these two components, they have been traditionally designed and analyzed independently of and separately from each other; namely, computer controllers by computer scientists/engineers and controlled processes by control scientists. As a remedy for this problem, in this report real-time computers are characterized by performance measures based on computer controller response time that are: (1) congruent to the real-time applications, (2) able to offer an objective comparison of rival computer systems, and (3) experimentally measurable/determinable. These measures, unlike others, provide the real-time computer controller with a natural link to controlled processes. In order to demonstrate their utility and power, these measures are first determined for example controlled processes on the basis of control performance functionals. They are then used for two important real-time multiprocessor design applications - the number-power tradeoff and fault-masking and synchronization.

  11. Three dimensional fusion of electromechanical mapping and magnetic resonance imaging for real-time navigation of intramyocardial cell injections in a porcine model of chronic myocardial infarction.

    PubMed

    van Slochteren, F J; van Es, R; Gyöngyösi, M; van der Spoel, T I G; Koudstaal, S; Leiner, T; Doevendans, P A; Chamuleau, S A J

    2016-05-01

    For cardiac regenerative therapy intramyocardial catheter guided cell transplantations are targeted to the infarct border zone (IBZ) i.e. the closest region of viable myocardium in the vicinity of the infarct area. For optimal therapeutic effect this area should be accurately identified. However late gadolinium enhanced magnetic resonance imaging (LGE-MRI) is the gold standard technique to determine the infarct size and location, electromechanical mapping (EMM) is used to guide percutaneous intramyocardial injections to the IBZ. Since EMM has a low spatial resolution, we aim to develop a practical and accurate technique to fuse EMM with LGE-MRI to guide intramyocardial injections. LGE-MRI and EMM were obtained in 17 pigs with chronic myocardial infarction created by balloon occlusion of LCX and LAD coronary arteries. LGE-MRI and EMM datasets were registered using our in-house developed 3D CartBox image registration software toolbox to assess: (1) the feasibility of the 3D CartBox toolbox, (2) the EMM values measured in the areas with a distinct infarct transmurality (IT), and (3) the highest sensitivity and specificity of the EMM to assess IT and define the IBZ. Registration of LGE-MRI and EMM resulted in a mean error of 3.01 ± 1.94 mm between the LGE-MRI mesh and EMM points. The highest sensitivity and specificity were found for UV <9.4 mV and bipolar voltage <1.2 mV to respectively identify IT of ≥5 and ≥97.5 %. The 3D CartBox image registration toolbox enables registration of EMM data on pre-acquired MRI during the EMM guided procedure and allows physicians to easily guide injections to the most optimal injection location for cardiac regenerative therapy and harness the full therapeutic effect of the therapy. PMID:26883433

  12. Three-dimensional carbon nanotube based photovoltaics

    NASA Astrophysics Data System (ADS)

    Flicker, Jack

    2011-12-01

    Photovoltaic (PV) cells with a three dimensional (3D) morphology are an exciting new research thrust with promise to create cheaper, more efficient solar cells. This work introduces a new type of 3D PV device based on carbon nanotube (CNT) arrays. These arrays are paired with the thin film heterojunction, CdTe/CdS, to form a complete 3D carbon nanotube PV device (3DCNTPV). Marriage of a complicated 3D structure with production methods traditionally used for planar CdTe solar cell is challenging. This work examines the problems associated with processing these types of cells and systematically alters production methods of the semiconductor layers and electrodes to increase the short circuit current (Isc), eliminate parasitic shunts, and increase the open circuit voltage (Voc). The main benefit of 3D solar cell is the ability to utilize multiple photon interactions with the solar cell surface. The three dimensionality allows photons to interact multiple times with the photoactive material, which increases the absorption and the overall power output over what is possible with a two dimensional (2D) morphology. To quantify the increased power output arising from these multiple photon interactions, a new absorption efficiency term, eta3D, is introduced. The theoretical basis behind this new term and how it relates to the absorption efficiency of a planar cell, eta 2D, is derived. A unique model for the average number of multiple photon impingements, Gamma, is proposed based on three categories of 3D morphology: an infinite trench, an enclosed box, and an array of towers. The derivation of eta3D and Gamma for these 3D PV devices gives a complete picture of the enhanced power output over 2D cells based on CNT array height, pitch, radius, and shape. This theory is validated by monte carlo simulations and experiment. This new type of 3D PV devices has been shown to work experimentally. The first 3DCNTPV cells created posses Isc values of 0.085 to 17.872mA/cm2 and Voc values

  13. Real-Time Gauge/Gravity Duality

    SciTech Connect

    Skenderis, Kostas; Rees, Balt C. van

    2008-08-22

    We present a general prescription for the holographic computation of real-time n-point functions in nontrivial states. In quantum field theory such real-time computations involve a choice of a time contour in the complex time plane. The holographic prescription amounts to 'filling in' this contour with bulk solutions: real segments of the contour are filled in with Lorentzian solutions while imaginary segments are filled in with Riemannian solutions and appropriate matching conditions are imposed at the corners of the contour. We illustrate the general discussion by computing the 2-point function of a scalar operator using this prescription and by showing that this leads to an unambiguous answer with the correct i{epsilon} insertions.

  14. Real-time DNA microarray analysis

    PubMed Central

    Hassibi, Arjang; Vikalo, Haris; Riechmann, José Luis; Hassibi, Babak

    2009-01-01

    We present a quantification method for affinity-based DNA microarrays which is based on the real-time measurements of hybridization kinetics. This method, i.e. real-time DNA microarrays, enhances the detection dynamic range of conventional systems by being impervious to probe saturation in the capturing spots, washing artifacts, microarray spot-to-spot variations, and other signal amplitude-affecting non-idealities. We demonstrate in both theory and practice that the time-constant of target capturing in microarrays, similar to all affinity-based biosensors, is inversely proportional to the concentration of the target analyte, which we subsequently use as the fundamental parameter to estimate the concentration of the analytes. Furthermore, to empirically validate the capabilities of this method in practical applications, we present a FRET-based assay which enables the real-time detection in gene expression DNA microarrays. PMID:19723688

  15. Real-time DNA microarray analysis.

    PubMed

    Hassibi, Arjang; Vikalo, Haris; Riechmann, José Luis; Hassibi, Babak

    2009-11-01

    We present a quantification method for affinity-based DNA microarrays which is based on the real-time measurements of hybridization kinetics. This method, i.e. real-time DNA microarrays, enhances the detection dynamic range of conventional systems by being impervious to probe saturation in the capturing spots, washing artifacts, microarray spot-to-spot variations, and other signal amplitude-affecting non-idealities. We demonstrate in both theory and practice that the time-constant of target capturing in microarrays, similar to all affinity-based biosensors, is inversely proportional to the concentration of the target analyte, which we subsequently use as the fundamental parameter to estimate the concentration of the analytes. Furthermore, to empirically validate the capabilities of this method in practical applications, we present a FRET-based assay which enables the real-time detection in gene expression DNA microarrays. PMID:19723688

  16. Video-rate three-dimensional optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Laubscher, Markus; Ducros, Mathieu; Karamata, Boris; Lasser, Theo; Salathe, Rene

    2002-05-01

    Most current optical coherence tomography systems provide two-dimensional cross-sectional or en face images. Successive adjacent images have to be acquired to reconstruct three-dimensional objects, which can be time consuming. Here we demonstrate three-dimensional optical coherence tomography (3D OCT) at video rate. A 58 by 58 smart-pixel detector array was employed. A sample volume of 210x210x80 m3 (corresponding to 58x58x58 voxels) was imaged at 25 Hz. The longitudinal and transverse resolutions are 3 m and 9 m respectively. The sensitivity of the system was 76 dB. Video rate 3D OCT is illustrated by movies of a strand of hair undergoing fast thermal damage.

  17. Identification of Jiangxi wines by three-dimensional fluorescence fingerprints

    NASA Astrophysics Data System (ADS)

    Wan, Yiqun; Pan, Fengqin; Shen, Mingyue

    2012-10-01

    A new assay of identifying wines was developed based on fingerprints of three-dimensional fluorescence spectra, and 30 samples from different manufacturers were analyzed. The techniques of principal component analysis (PCA) and hierarchical cluster analysis (HCA) were used to differentiate and evaluate the character parameters of wines' three-dimensional fluorescence spectra. At the same time, the back-propagation network (BPN) was applied to predict the attribution of unknown samples. The results of PCA and HCA showed that there was definite different information among the wine samples from different manufacturers. It was promising that the method could be applied to distinguish wine samples produced by different manufacturers. The proposed method could provide the criterion for the quality control of wines.

  18. Granular temperature profiles in three-dimensional vibrofluidized granular beds

    SciTech Connect

    Wildman, R. D.; Huntley, J. M.; Parker, D. J.

    2001-06-01

    The motion of grains in a three-dimensional vibrofluidized granular bed has been measured using the technique of positron emission particle tracking, to provide three-dimensional packing fraction and granular temperature distributions. The mean square fluctuation velocity about the mean was calculated through analysis of the short time mean squared displacement behavior, allowing measurement of the granular temperature at packing fractions of up to {eta}{similar_to}0.15. The scaling relationship between the granular temperature, the number of layers of grains, and the base velocity was determined. Deviations between the observed scaling exponents and those predicted by recent theories are attributed to the influence of dissipative grain-sidewall collisions.

  19. Three-dimensional mapping and regulation of action potential propagation in nanoelectronics-innervated tissues

    NASA Astrophysics Data System (ADS)

    Dai, Xiaochuan; Zhou, Wei; Gao, Teng; Liu, Jia; Lieber, Charles M.

    2016-09-01

    Real-time mapping and manipulation of electrophysiology in three-dimensional (3D) tissues could have important impacts on fundamental scientific and clinical studies, yet realization is hampered by a lack of effective methods. Here we introduce tissue-scaffold-mimicking 3D nanoelectronic arrays consisting of 64 addressable devices with subcellular dimensions and a submillisecond temporal resolution. Real-time extracellular action potential (AP) recordings reveal quantitative maps of AP propagation in 3D cardiac tissues, enable in situ tracing of the evolving topology of 3D conducting pathways in developing cardiac tissues and probe the dynamics of AP conduction characteristics in a transient arrhythmia disease model and subsequent tissue self-adaptation. We further demonstrate simultaneous multisite stimulation and mapping to actively manipulate the frequency and direction of AP propagation. These results establish new methodologies for 3D spatiotemporal tissue recording and control, and demonstrate the potential to impact regenerative medicine, pharmacology and electronic therapeutics.

  20. Quantitative Real-Time PCR: Recent Advances.

    PubMed

    Singh, Charanjeet; Roy-Chowdhuri, Sinchita

    2016-01-01

    Quantitative real-time polymerase chain reaction is a technique for simultaneous amplification and product quantification of a target DNA as the process takes place in real time in a "closed-tube" system. Although this technique can provide an absolute quantification of the initial template copy number, quantification relative to a control sample or second sequence is typically adequate. The quantification process employs melting curve analysis and/or fluorescent detection systems and can provide amplification and genotyping in a relatively short time. Here we describe the properties and uses of various fluorescent detection systems used for quantification. PMID:26843055