Science.gov

Sample records for recherche zur ermittlung

  1. Recherche de leptons lourds au LEP 2

    NASA Astrophysics Data System (ADS)

    Tafirout, Reda

    En 1989, la mise en opération de la première phase du LEP (le LEP 1), au CERN, a une Energie correspondant a la résonance du boson Z0, a permis d'étudier et de confirmer avec une grande précision le Modèle Standard des interactions électrofaibles. Malgré le succès remarquable de ce modèle à décrire toutes les données expérimentales recueillies jusqu'à ce jour en physique des hautes énergies, ce dernier laisse plusieurs questions sans réponse. Il n'explique pas entre autres pourquoi il n'y a que trois familles de particules dont le neutrino associé est léger et la hiérarchie des masses observées des fermions reste une énigme. Ici, nous nous intéressons à l'existence éventuelle de nouveaux fermions, tels que prédits par des extensions du Modèle Standard. Ces nouveaux fermions ont été recherches au LEP 1, mais en vain, et une limite inférieure sur leur masse d'environ MZ/2 a pu être imposée. La deuxième phase du LEP (le LEP 2) qui a débuté dans l'automne 1995 avec une énergie disponible de √s = 130, et 136 GeV, puis dans l'été 1996 a √s = 161 GeV a permis d'améliorer ces limites. Nous présentons ici la recherche de leptons lourds, neutres (N) et chargés (L+/-), effectuée à partir des données recueillies dans l'automne 1996 avec le détecteur de la collaboration OPAL au LEP 2, à des énergies au centre de masse de √s = 170 et 172 GeV. La luminosité totale intégrée fut de 10.3 pb-1. Un nouveau générateur, EXOTIC, conçu et développé a cette fin, a été utilise pour la simulation des échantillons d'événements Monte Carlo qui ont servi à comparer les données obtenues avec les prédictions théoriques. Plus spécifiquement, nous avons recherché le processus e+e- --> NN où N, pouvant être de type Dirac ou Majorana, se désintègre en un lepton léger standard (e, μ, ou τ) et un boson W+/- virtuel (W+/-*). Pour un N de type Dirac, une limite inférieure sur la masse à 95% de niveau de confiance est obtenue

  2. Education Relative a l'Environnement: Regards, Recherches, Reflexions. Volume 1.

    ERIC Educational Resources Information Center

    1999

    This document reports the work of an inter-university colloquium in Montreal in November, 1997 on research on the evaluation of education relative to the environment. Papers include: (1) "Un "patrimoine" de recherche en construction" (Lucie Sauve); (2) "Pour une recherche en education relative l'environnement "centree sur l'objet partage"" (Louis…

  3. Education Relative a l'Environnement: Regards, Recherches, Reflexions. Volume 1.

    ERIC Educational Resources Information Center

    1999

    This document reports the work of an inter-university colloquium in Montreal in November, 1997 on research on the evaluation of education relative to the environment. Papers include: (1) "Un "patrimoine" de recherche en construction" (Lucie Sauve); (2) "Pour une recherche en education relative l'environnement "centree sur l'objet partage"" (Louis…

  4. Recherche et Analyse de Galaxies Brilliantes EN Exces EN Ultraviolet

    NASA Astrophysics Data System (ADS)

    Coziol, Roger

    Dans ce travail, nous decrivons et presentons les resultats du sondage Montreal Blue Galaxy (MBG) visant la recherche de galaxies emettant en exces en ultraviolet. Cette recherche utilise le materiel photographique du sondage MCT (Montreal-Cambridge-Tololo) qui par son etendue correspond a un des plus importants sondages de l'hemisphere austral. Le sondage MBG est presentement le seul dans cet hemisphere a employer la technique de poses multiples pour la selection de ses candidats. Grace a cette technique, nous avons l'occasion d'etudier un echantillon de galaxies ayant des caracteristiques quelque peu differentes de celles des echantillons analyses auparavant. Deux phenomenes peuvent expliquer l'exces d'ultraviolet observe dans ces galaxies. Le premier suppose la presence dans leur noyau d'un trou noir massif. Toutes les galaxies sujettes a ce type d'activite sont regroupees sous le nom de galaxies avec noyau actif (AGN). Le deuxieme phenomene est relie a une periode de formation intense d'etoiles, ou sursaut de formation d'etoiles ("starburst"). L'exces d'ultraviolet trahit ici la presence d'un grand nombre d'etoiles massives recemment creees au sein de ces galaxies. En plus d'augmenter le nombre d'AGN connues, les sondages de galaxies brillantes en ultraviolet permettent aussi d'approfondir les questions specifiques suivantes: combien y a-t'il de galaxies starbursts differentes? Quelle est l'origine possible de leur activite? Quel est le role des sursauts de formation d'etoiles dans la vie d'une galaxie? Quel est le lien entre les galaxies starbursts et les AGN?. L'analyse de notre echantillon de galaxies se fait par l'entremise de plusieurs methodes. La premiere consiste a obtenir des spectres optiques de nos candidats. L'etude de ces spectres nous permet de distinguer entre les AGN et les galaxies starbursts et de deduire plusieurs parametres physiques importants. Notre deuxieme methode consiste a obtenir des images. Ceci nous permet d'avoir une idee de la

  5. Les enjuex éthiques entourant la recherche en santé sur les enfants

    PubMed Central

    2008-01-01

    RÉSUMÉ La recherche en santé est un devoir moral parce qu’elle est la base des soins probants prodigués par tous les dispensateurs de soins. Des politiques et des règlements précis régissent la tenue des recherches sur des humains. Il faut procéder à une évaluation éthique d’un projet de recherche donné avant de pouvoir l’entreprendre. La recherche sur les enfants pose d’énormes défis en matière de consentement éclairé et d’assentiment, de vulnérabilité et de potentiel de conflit d’intérêts (CDI). Les chercheurs en santé pédiatrique devraient prôner la participation des enfants à la recherche, tout en se montrant attentifs à en limiter les risques.

  6. Newtons Universum. Materialien zur Geschichte des Kraftbegriffes.

    NASA Astrophysics Data System (ADS)

    Mit einem Vorwort von E. Seibold und einer Einführung von W. Neuser. This book is a selection of 15 articles published in the journal "Spektrum der Wissenschaft". The original English versions of the papers were first published in "Scientific American". Contents: 1. Impetustheorie und Intuition in der Physik (M. McCloskey). 2. Mittelalterliche Ursprünge der industriellen Revolution (T. S. Reynolds). 3. Leonardo da Vincis Beiträge zur theoretischen Mechanik (V. Foley, W. Soedel). 4. Nikolaus Kopernikus und Tycho Brahe (O. Gingerich). 5. Keplers Entdeckung der ersten beiden Planetengesetze (C. Wilson). 6. Galileis Entdeckung des Fallgesetzes (S. Drake). 7. Galileis Beobachtung des Neptun (S. Drake, C. T. Kowal). 8. Galileo Galilei und der Schatten des Giordano Bruno (L. S. Lerner, E. A. Gosselin). 9. Der Fall Galilei (O. Gingerich). 10. Newtons Apfel und Galileis "Dialog" (S. Drake). 11. Newtons Gravitationsgesetz - aus Formeln wird eine Idee (I. B. Cohen). 12. Christopher Wren: Astronom und Architekt (H. Dorn, R. Mark). 13. Atomismus und Kräfte in der Geschichte (L. Holliday). 14. Ein Elitezirkel vor 200 Jahren: Die Lunar Society von Birmingham (L. Ritchie-Calder). 15. Sadi Carnot: Technik und Theorie der Dampfmaschine (S. S. Wilson).

  7. Structural and Mechanistic Basis of Zinc Regulation Across the E. coli Zur Regulon

    PubMed Central

    Gilston, Benjamin A.; Wang, Suning; Marcus, Mason D.; Canalizo-Hernández, Mónica A.; Swindell, Elden P.; Xue, Yi; Mondragón, Alfonso; O'Halloran, Thomas V.

    2014-01-01

    Commensal microbes, whether they are beneficial or pathogenic, are sensitive to host processes that starve or swamp the prokaryote with large fluctuations in local zinc concentration. To understand how microorganisms coordinate a dynamic response to changes in zinc availability at the molecular level, we evaluated the molecular mechanism of the zinc-sensing zinc uptake regulator (Zur) protein at each of the known Zur-regulated genes in Escherichia coli. We solved the structure of zinc-loaded Zur bound to the PznuABC promoter and show that this metalloregulatory protein represses gene expression by a highly cooperative binding of two adjacent dimers to essentially encircle the core element of each of the Zur-regulated promoters. Cooperativity in these protein-DNA interactions requires a pair of asymmetric salt bridges between Arg52 and Asp49′ that connect otherwise independent dimers. Analysis of the protein-DNA interface led to the discovery of a new member of the Zur-regulon: pliG. We demonstrate this gene is directly regulated by Zur in a zinc responsive manner. The pliG promoter forms stable complexes with either one or two Zur dimers with significantly less protein-DNA cooperativity than observed at other Zur regulon promoters. Comparison of the in vitro Zur-DNA binding affinity at each of four Zur-regulon promoters reveals ca. 10,000-fold variation Zur-DNA binding constants. The degree of Zur repression observed in vivo by comparison of transcript copy number in wild-type and Δzur strains parallels this trend spanning a 100-fold difference. We conclude that the number of ferric uptake regulator (Fur)-family dimers that bind within any given promoter varies significantly and that the thermodynamic profile of the Zur-DNA interactions directly correlates with the physiological response at different promoters. PMID:25369000

  8. Regulation and Activity of a Zinc Uptake Regulator, Zur, in Corynebacterium diphtheriae▿

    PubMed Central

    Smith, Kelsy F.; Bibb, Lori A.; Schmitt, Michael P.; Oram, Diana M.

    2009-01-01

    Regulation of metal ion homeostasis is essential to bacterial cell survival, and in most species it is controlled by metal-dependent transcriptional regulators. In this study, we describe a Corynebacterium diphtheriae ferric uptake regulator-family protein, Zur, that controls expression of genes involved in zinc uptake. By measuring promoter activities and mRNA levels, we demonstrate that Zur represses transcription of three genes (zrg, cmrA, and troA) in zinc-replete conditions. All three of these genes have similarity to genes involved in zinc uptake. Transcription of zrg and cmrA was also shown to be regulated in response to iron and manganese, respectively, by mechanisms that are independent of Zur. We demonstrate that the activity of the zur promoter is slightly decreased under low zinc conditions in a process that is dependent on Zur itself. This regulation of zur transcription is distinctive and has not yet been described for any other zur. An adjacent gene, predicted to encode a metal-dependent transcriptional regulator in the ArsR/SmtB family, is transcribed from a separate promoter whose activity is unaffected by Zur. A C. diphtheriae zur mutant was more sensitive to peroxide stress, which suggests that zur has a role in protecting the bacterium from oxidative damage. Our studies provide the first evidence of a zinc specific transcriptional regulator in C. diphtheriae and give new insights into the intricate regulatory network responsible for regulating metal ion concentrations in this toxigenic human pathogen. PMID:19074382

  9. Regulation and activity of a zinc uptake regulator, Zur, in Corynebacterium diphtheriae.

    PubMed

    Smith, Kelsy F; Bibb, Lori A; Schmitt, Michael P; Oram, Diana M

    2009-03-01

    Regulation of metal ion homeostasis is essential to bacterial cell survival, and in most species it is controlled by metal-dependent transcriptional regulators. In this study, we describe a Corynebacterium diphtheriae ferric uptake regulator-family protein, Zur, that controls expression of genes involved in zinc uptake. By measuring promoter activities and mRNA levels, we demonstrate that Zur represses transcription of three genes (zrg, cmrA, and troA) in zinc-replete conditions. All three of these genes have similarity to genes involved in zinc uptake. Transcription of zrg and cmrA was also shown to be regulated in response to iron and manganese, respectively, by mechanisms that are independent of Zur. We demonstrate that the activity of the zur promoter is slightly decreased under low zinc conditions in a process that is dependent on Zur itself. This regulation of zur transcription is distinctive and has not yet been described for any other zur. An adjacent gene, predicted to encode a metal-dependent transcriptional regulator in the ArsR/SmtB family, is transcribed from a separate promoter whose activity is unaffected by Zur. A C. diphtheriae zur mutant was more sensitive to peroxide stress, which suggests that zur has a role in protecting the bacterium from oxidative damage. Our studies provide the first evidence of a zinc specific transcriptional regulator in C. diphtheriae and give new insights into the intricate regulatory network responsible for regulating metal ion concentrations in this toxigenic human pathogen.

  10. Une formation à la recherche en médecine transfusionnelle dans le monde francophone

    PubMed Central

    Shiboski, C.; Fontanet, A.; Murphy, E.L.

    2010-01-01

    Un enseignement accéléré et francophone de formation à la recherche en médecine transfusionnelle a été récemment instauré à l’Institut Pasteur de Paris, sous la codirection de membres hospitalo-universitaires de l’université de Californie San Francisco (UCSF), du Blood Systems Research Institute (BSRI) et de l’Institut national de la transfusion sanguine (INTS). Le but est de former des professionnels de la transfusion des pays en voie de développement à mener une activité de recherche dont les résultats peuvent contribuer à un renforcement de la qualité des soins transfusionnels et de la sécurité transfusionnelle dans leur pays. Le cours enseigne les méthodes de recherche clinique et épidémiologique, et leurs applications transfusionnelles potentielles. Chaque étudiant élabore au cours du stage un protocole personnel de recherche, qu’il lui sera loisible de mettre ensuite en pratique dans le centre de transfusion ou l’hôpital où il exerce. PMID:19640755

  11. Education Relative a l'Environnement: Regards, Recherches, Reflexions. Volume 3.

    ERIC Educational Resources Information Center

    2002

    This volume presents the work of a colloquium on the theme "Education a l'environnement: Mouveaux publics, mouveax partenaires" that took place May 3-4, 2000 in Poitiers. Papers include: (1) "Pourquoi rechercher de nouvezus publics pour l'education relative a l'environnement?" (Louis Goffin); (2) "Le partenariat en education relative a…

  12. Education Relative a l'Environnement: Regards, Recherches, Reflexions. Volume 3.

    ERIC Educational Resources Information Center

    2002

    This volume presents the work of a colloquium on the theme "Education a l'environnement: Mouveaux publics, mouveax partenaires" that took place May 3-4, 2000 in Poitiers. Papers include: (1) "Pourquoi rechercher de nouvezus publics pour l'education relative a l'environnement?" (Louis Goffin); (2) "Le partenariat en education relative a…

  13. Le partenariat en recherche: un véhicule pour atteindre les plus hauts sommets.

    PubMed

    Gélinas, Isabelle

    2016-10-01

    Les partenariats en ergothérapie entre les praticiens et les chercheurs sont importants pour produire des connaissances pertinentes pour la pratique clinique et pour favoriser la pratique fondée sur les données probantes au sein de la profession. BUT: Dans ce discours Muriel Driver, l'auteure discute des raisons pour lesquelles nous devons favoriser la participation des praticiens à la recherche et elle examine les conditions essentielles à la réussite des partenariats de recherche en collaboration. QUESTIONS CLÉS: Les partenariats de collaboration peuvent réduire les obstacles empêchant les praticiens de participer à la recherche et permettre de veiller à ce que les initiatives de recherche soient plus pertinentes pour la pratique clinique. Les facteurs clés pour établir et maintenir des partenariats significatifs sont la présence de conditions préalables et favorables au partenariat en lien avec le contexte, de même que l'utilisation de principes directeurs axés sur la vision, les valeurs, la confiance, la communication, le partage du pouvoir et les interactions. CONSÉQUENCES: Plusieurs des facteurs identifiés comme étant favorables à la réussite d'un partenariat de collaboration correspondent aux rôles fondamentaux des ergothérapeutes et témoignent de nos valeurs professionnelles. La prise en compte de ces facteurs lors de l'établissement de collaborations de recherche permettrait d'accroître les probabilités de réussite. © CAOT 2016.

  14. Acinetobacter baumannii Response to Host-Mediated Zinc Limitation Requires the Transcriptional Regulator Zur

    PubMed Central

    Mortensen, Brittany L.; Rathi, Subodh; Chazin, Walter J.

    2014-01-01

    Acinetobacter baumannii is a leading cause of ventilator-associated pneumonia in intensive care units, and the increasing rates of antibiotic resistance make treating these infections challenging. Consequently, there is an urgent need to develop new antimicrobials to treat A. baumannii infections. One potential therapeutic option is to target bacterial systems involved in maintaining appropriate metal homeostasis, processes that are critical for the growth of pathogens within the host. The A. baumannii inner membrane zinc transporter ZnuABC is required for growth under low-zinc conditions and for A. baumannii pathogenesis. The expression of znuABC is regulated by the transcriptional repressor Zur. To investigate the role of Zur during the A. baumannii response to zinc limitation, a zur deletion mutant was generated, and transcriptional changes were analyzed using RNA sequencing. A number of Zur-regulated genes were identified that exhibit increased expression both when zur is absent and under low-zinc conditions, and Zur binds to predicted Zur box sequences of several genes affected by zinc levels or the zur mutation. Furthermore, the zur mutant is impaired for growth in the presence of both high and low zinc levels compared to wild-type A. baumannii. Finally, the zur mutant exhibits a defect in dissemination in a mouse model of A. baumannii pneumonia, establishing zinc sensing as a critical process during A. baumannii infection. These results define Zur-regulated genes within A. baumannii and demonstrate a requirement for Zur in the A. baumannii response to the various zinc levels experienced within the vertebrate host. PMID:24816603

  15. Ansätze zur Ordnungsreduktion von nichtlinearen Oszillatormodellen zur Anwendung im Schaltungsentwurf

    NASA Astrophysics Data System (ADS)

    Reit, M.; Bremer, J.-K.; Mathis, W.; Stoop, R.

    2010-10-01

    Im Rahmen dieser Arbeit wird ein Konzept zur Ordnungsreduktion von höherdimensionalen nichtlinearen Oszillatormodellen vorgestellt. Hierbei werden zwei wesentliche Ziele verfolgt. Zum einen wird eine höherdimensionale Modellierung der Oszillatorschaltung verwendet. Hierdurch lassen sich die Einflüsse parasitärer Effekte sowie struktureller Erweiterungen auf das dynamische Verhalten des Systems berücksichtigen. Zum anderen wird durch eine anschließende Ordnungsreduktion über die Methode der Zentrumsmannigfaltigkeit eine zweidimensionale Systembeschreibung erzeugt, deren wesentliche Dynamik derjenigen des höherdimensionalen Systems entspricht. Durch diese, in der Ordnung reduzierte, nichtlineare und parameterabhängige Systembeschreibung wird die Anwendbarkeit nichtlinearer Analysemethoden ermöglicht bzw. vereinfacht. Mit der Anwendung der Andronov-Hopf-Bifurkationsanalyse auf das reduzierte System lässt sich eine Stabilitätsuntersuchung durchführen sowie die Amplitude und Frequenz aller Zustandsgrößen approximieren. Das vorgestellte Konzept wird anhand des Beispielsystems eines LC-Tank-VCOs durchgeführt. In this paper, an order reduction technique for higher-dimensional nonlinear oscillator models, based on a center manifold approach, is presented. By modeling the oscillator circuit in the higher-dimensional state space, influences of parasitic elements and of structural extensions of the oscillator architecture on the dynamical system behavior can be examined. Using the proposed order reduction technique, a generalized second order model will be derived, which includes selected design parameters of the higher order model. By using an Andronov-Hopf bifurcation analysis, the reduced system can be studied with respect to stability as well as the amplitude and frequency of the individual state variables. The concept is applied to the design of LC-tank VCOs.

  16. Vom Referat bis zur Examensarbeit: Naturwissenschaftliche Texte perfekt verfassen und gestalten

    NASA Astrophysics Data System (ADS)

    Kremer, Bruno P.

    Welches Thema eignet sich für mein Referat oder meine Seminararbeit? Wie sammle ich Stoff? Wie gliedere ich den Text? Bruno P. Kremer beantwortet auf nur 200 Seiten alle wichtigen Fragen zur wissenschaftlichen Arbeit in den naturwissenschaftlichen Fächern. Dabei beschränkt er sich auf das für Studenten und Schüler wirklich notwendige Wissen und lässt jeglichen unnützen Ballast beiseite. Dieser praktische Ratgeber verhilft Ihnen zur erfolgreichen wissenschaftlichen Arbeit - vom Referat bis zur Examensarbeit.

  17. S1-Leitlinie zur UV-Phototherapie und Photochemotherapie.

    PubMed

    Herzinger, Thomas; Berneburg, Mark; Ghoreschi, Kamran; Gollnick, Harald; Hölzle, Erhard; Hönigsmann, Herbert; Lehmann, Percy; Peters, Thorsten; Röcken, Martin; Scharffetter-Kochanek, Karin; Schwarz, Thomas; Simon, Jan; Tanew, Adrian; Weichenthal, Michael

    2016-08-01

    Die heilsame Wirkung des Sonnenlichts war teilweise schon im Altertum bekannt und fand in der zweiten Hälfte des 19. Jahrhunderts wieder zunehmend Beachtung. Den Beginn der modernen Phototherapien markiert die Entwicklung einer Apparatur zur ultravioletten Bestrahlung der Hauttuberkulose durch Finnsen zu Beginn des zwanzigsten Jahrhunderts. Zur Therapie von Hauterkrankungen finden beinahe ausschließlich die spektralen Bereiche unterhalb des sichtbaren Lichtes (ultraviolett) Anwendung. Seit den 1970er Jahren stehen zunehmend leistungsfähige künstliche Strahlenquellen bereit für die Therapie mit UVB, UVA und die Kombination von UVA mit Photosensibilisatoren (Photochemotherapie). Hohe strukturelle und prozedurale Qualitätsstandards sind unabdingbare Voraussetzung für die Durchführung einer gleichermaßen wirkungsvollen wie auch sicheren Phototherapie. Die Leitlinie formuliert den aktuellen Konsens führender Experten auf dem Gebiet der Phototherapie in Bezug auf die Indikationen für die jeweiligen Therapieverfahren, deren Gegenanzeigen und Nebenwirkungen und insbesondere für die Wahl der korrekten Dosis zu Beginn und im Verlauf einer Therapie sowie das Management von Nebenwirkungen. © 2016 The Authors | Journal compilation © Blackwell Verlag GmbH, Berlin.

  18. Molecular logic of the Zur-regulated zinc deprivation response in Bacillus subtilis

    PubMed Central

    Shin, Jung-Ho; Helmann, John D.

    2016-01-01

    Bacteria respond dynamically to the changes in zinc availability. Repression by the Bacillus subtilis transcription factor Zur requires Zn(II), which binds with negative cooperativity to two regulatory sites per dimer to form, sequentially, Zur2:Zn3 and Zur2:Zn4 forms of the repressor. Here we show that, as cells transition from zinc sufficiency to deficiency, operons regulated by Zur are derepressed in three distinct waves. The first includes the alternative RpmEB(L31*) and RpmGC(L33*) ribosomal proteins, which mobilize zinc from the ribosome, whereas the second includes the ZnuACB uptake system and the YciC metallochaperone. Finally, as zinc levels decrease further, the Zur2:Zn3 form loses Zn(II) leading to derepression of RpsNB(S14*) and FolE2, which allow continued ribosome assembly and folate synthesis, respectively. We infer that zinc mobilization from intracellular zinc stores takes priority over energy-dependent import, and our results link the biochemistry of zinc sensing by Zur to the molecular logic of the zinc deprivation response. PMID:27561249

  19. Ein Organic Computing Ansatz zur Steuerung einer sechsbeinigen Laufmaschine

    NASA Astrophysics Data System (ADS)

    Auf, Adam El Sayed; Larionova, Svetlana; Mösch, Florian; Litza, Marek; Jakimovski, Bojan; Maehle, Erik

    Obwohl die Rechengeschwindigkeit von Computern und die Komplexität unserer Systeme ständig zunimmt, sind die heutigen Laufmaschinen nicht in der Lage, sich mit den Fähigkeiten von Landtieren wie zum Beispiel Insekten zu messen. Das Verständnis biologischer Konzepte und das Lernen von der Natur könnten zur Verbesserung der heutigen Maschinen beitragen und sie ein wenig “lebensähnlicher“ machen. Dieser Artikel stellt einen Kontrollarchitekturansatz basierend auf “Organic Computing“-Prinzipien vor, der die Nutzung von Dezentralisierung und Selbstorganisation an einer sechsbeinigen Laufmaschine demonstriert. Die vorliegende Arbeit erklärt die elementaren Mechanismen für das gerade Laufen, das Kurvenlaufen sowie das Drehen auf der Stelle und den Umgang mit strukturellen körperlichen Änderungen wie einer Beinamputation und stellt die Ergebnisse experimenteller Versuche vor.

  20. Ein routine-integrierbares Planungswerkzeug zur operativen Rekonstruktion der Orbita

    NASA Astrophysics Data System (ADS)

    Kleiner, Melanie; Schulze, Dirk; Voss, Pit Jakob; Deserno, Thomas M.

    Bei Frakturen des Orbitabodens kann ein Titangitter zur Rekonstruktion operativ eingesetzt werden. In dieser Arbeit wird ein Planungswerkzeug entwickelt, welches mit Hilfe eines aktiven Konturmodells die Orbita in CT Daten segmentiert, ihr Volumen berechnet und visualisiert. Neben den technischen Integrationsstufen der Funktions- und Präsentationsintegration, welche durch den Einsatz des Medical Imaging Interaction Toolkit (MITK) erreicht werden, sowie der Daten-, und Kontextintegration ist vor allem die Stabilität der eingesetzten Algorithmik für die Routine-Integrierbarkeit wichtig. Erste Stabilitätsuntersuchungen basieren auf 3 von 100 zufällig ausgewählten CT-Datensätzen, wobei das Volumen mit je 50 verschiedenen Startpunkten berechnet wurde. Die so ermittelten Variationskoeffizienten liegen deutlich unterhalb der kritischen 5 % Schwelle.

  1. [Pierre Bourdieu and health: a sociological analysis of Actes de la Recherche en Sciences Sociales].

    PubMed

    Montagner, Miguel Angelo

    2008-07-01

    This study aimed to highlight, illustrate, describe, and comment on the presence of the health category in the work of Pierre Bourdieu, by underlining the themes traditionally related to the sociology of the body. After a systematic analysis of his work in the sociology of medicine and health, the article also addresses the main vehicle for his line of thought, namely Actes de la Recherche en Sciences Sociales, viewed here as the prime channel for most of the research taking Bourdieu's "genetic structuralism" as the main theoretical reference. We analyze the articles published from 1975 to 2001, from the thematic and theoretical/conceptual perspective, by comparing the changes appearing in this journal in opposition to the model previously adopted by the Revue Française de Sociologie.

  2. A la recherches d'autres mondes - les exoplanètes

    NASA Astrophysics Data System (ADS)

    Nazé, Yaël

    2013-10-01

    Habiter ailleurs que sur Terre, en dehors du système solaire, est-ce vraiment possible ? Est-ce que la vie existe en dehors du Système solaire et comment la chercher ? Ces questions sont celles que les hommes et les femmes se posent et celles qu'ils se sont posées de tout temps. Les scientifiques n'échappent pas à cette règle et nous vivons à une époque fascinante où cette recherche évolue extrêmement vite : ils ont découvert d'autres lieux potentiellement habitables ou habités, les exoplanètes, des planètes tournant autour d'autres soleils dans l'univers. À ce jour, plus de 900 exoplanètes ont ainsi été détectées

  3. Eine selbstkonsistente Carleman Linearisierung zur Analyse von Oszillatoren

    NASA Astrophysics Data System (ADS)

    Weber, Harry; Mathis, Wolfgang

    2017-09-01

    Die Analyse nichtlinearer dynamischer Schaltungen ist bis heute eine herausfordernde Aufgabe, da nur selten analytische Lösungen angegeben werden können. Daher wurden eine Vielzahl von Methoden entwickelt, um eine qualitative oder quantitative Näherung für die Lösungen der Netzwerkgleichung zu erhalten. Oftmals wird beispielsweise eine Kleinsignalanalyse mit Hilfe einer Taylorreihe in einem Arbeitspunkt durchgeführt, die nach den Gliedern erster Ordnung abgebrochen wird. Allerdings ist diese Linearisierung nur in der Nähe des stabilen Arbeitspunktes für hyperbolische Systeme gültig. Besonders für die Analyse des dynamischen Verhaltens von Oszillatoren treten jedoch nicht-hyperbolische Systeme auf, sodass diese Methode nicht angewendet werden kann Mathis(2000). Carleman hat gezeigt, dass nichtlineare Differentialgleichungen mit polynomiellen Nichtlinearitäten in ein unendliches System von linearen Differentialgleichungen transformiert werden können Carleman(1932). Wird das unendlichdimensionale Gleichungssystem für numerische Zwecke abgebrochen, kann bei Oszillatoren der Übergang in eine stationäre Schwingung (Grenzzyklus) nicht wiedergegeben werden.

    In diesem Beitrag wird eine selbstkonsistente Carleman Linearisierung zur Untersuchung von Oszillatoren vorgestellt, die auch dann anwendbar ist, wenn die Nichtlinearitäten keinen Polynomen entsprechen. Anstelle einer linearen Näherung um einen Arbeitspunkt, erfolgt mit Hilfe der Carleman Linearisierung eine Approximation auf einem vorgegebenen Gebiet. Da es jedoch mit der selbstkonsistenten Technik nicht möglich ist, das stationäre Verhalten von Oszillatoren zu beschreiben, wird die Berechnung einer Poincaré-Abbildung durchgeführt. Mit dieser ist eine anschließende Analyse des Oszillators möglich.

  4. Zur (FurB) is a key factor in the control of the oxidative stress response in Anabaena sp. PCC 7120.

    PubMed

    Sein-Echaluce, Violeta C; González, Andrés; Napolitano, Mauro; Luque, Ignacio; Barja, Francisco; Peleato, M Luisa; Fillat, María F

    2015-06-01

    Iron and zinc are necessary nutrients whose homeostasis is tightly controlled by members of the ferric uptake regulator (FUR) superfamily in the cyanobacterium Anabaena sp. PCC7120. Although the link between iron metabolism and oxidative stress management is well documented, little is known about the connection between zinc homeostasis and the oxidative stress response in cyanobacteria. Zinc homeostasis in Anabaena is controlled by Zur, also named FurB. When overexpressed in Escherichia coli, Zur (FurB) improved cell survival during oxidative stress. In order to investigate the possible correlation between Zur and the oxidative stress response in Anabaena, zur deletion and zur-overexpressing strains have been constructed, and the consequences of Zur imbalance evaluated. The lack of Zur increased sensitivity to hydrogen peroxide (H2 O2 ), whereas an excess of Zur enhanced oxidative stress resistance. Both mutants displayed pleiotropic phenotypes, including alterations on the filament surfaces observable by scanning electron microscopy, reduced content of endogenous H2 O2 and altered expression of sodA, catalases and several peroxiredoxins. Transcriptional and biochemical analyses unveiled that the appropriate level of Zur is required for proper control of the oxidative stress response and allowed us to identify major antioxidant enzymes as novel members of the Zur regulon.

  5. Le changement comme tradition dans la recherche et la formation a la recherche en biotechnologie et en peripherie Etude de cas en sciences de la sante, sciences naturelles et genie

    NASA Astrophysics Data System (ADS)

    Bourque, Claude Julie

    Le champ de la recherche scientifique et de la formation a la recherche est traverse depuis quelques dizaines d'annees par plusieurs courants et discours associes au changement, mais peu de travaux empiriques permettent de comprendre ce qui change concretement. C'est la contribution originale de cette these au champ de l'education, plus specifiquement a l'etude sociologique de l'enseignement superieur ou sont concentrees les activites liees a la triade thematique du programme doctoral dans lequel elle a ete produite : recherche, formation et pratique. L'enquete-terrain a ete realisee en 2009 et 2010 aupres de 808 repondants affilies a 60 etablissements au Quebec et a produit un vaste materiau de nature mixte (donnees quantitatives et qualitatives). Un portrait de la nebuleuse biotechnologique qui touche les secteurs des sciences de la sante, des sciences naturelles et du genie a ete realise. Ce domaine concerne des dizaines de disciplines et se revele de nature transdisciplinaire, mais les pratiques n'y sont pas davantage marquees par le changement que celles d'autres domaines connexes. Les dynamiques sociales ont fait l'objet d'analyses comparatives dans quatre contextes: le choix des programmes, des objets et des methodes, le financement, la diffusion et la planification de la carriere. Les resultats indiquent que les echanges entre les agents traditionnellement situes au coeur des activites de recherche dominent ces dynamiques dans tous les contextes etudies. L'etude des representations au fondement des pratiques a revele l'existence de trois ecoles de pensee qui coexistent dans le champ scientifique: academique, pragmatique et economiste. Ces ecoles permettent de categoriser les agents en fonction des zones de fractures qui marquent leurs oppositions tout en identifiant ce qu'ils ont en commun. Les representations et les pratiques liees a la formation temoignent d'un habitus plutot homogene, alors que les contradictions semblent plus souvent ancrees dans des

  6. Le groupe de recherches transfusionnelles d’Afrique francophone: bilan des cinq premières années

    PubMed Central

    Tagny, Claude Tayou; Murphy, Edward L.; Lefrère, Jean-Jacques

    2016-01-01

    Les travaux de recherches sur la sécurité transfusionnelle en Afrique sub-saharienne sont peu nombreux, souvent limités à des initiatives locales avec des conclusions difficilement représentatives de cette région. Le Groupe de recherches transfusionnelles en Afrique sub-saharienne francophone a été créé en mai 2007 avec pour objectif de développer des stratégies globales d’amélioration de la sécurité transfusionnelle mais adaptables à la situation de chaque pays. Les activités du Groupe à ce jour ont porté essentiellement sur l’obtention de données épidémiologiques et de laboratoire sur la transfusion sanguine et à proposer des stratégies de sécurité transfusionnelle dans le domaine des infections transmissibles par la transfusion. Pour mener à bien ces activités de recherche, le Groupe travaille en étroite collaboration avec les Centres nationaux de transfusion sanguine (CNTS), les Centres régionaux de transfusion sanguine (CRTS), les banques de sang hospitalières (BSH) et les postes de collecte de sang. Pour les 5 premières années, quatre priorités de recherche ont été identifiées: (i) des études descriptives sur les caractéristiques des donneurs de sang et des centres de transfusion; (ii) une estimation du risque résiduel post-transfusionnel des principales infections virales transmissibles par la transfusion; (iii) une analyse des stratégies de sélection médicale des donneurs de sang; et (iv) une description des stratégies de dépistage des ITT et une description du système d’assurance qualité externe existant. Durant cette période, sept projets ont été mis en œuvre au niveau national et publiés et cinq études multicentriques ont été réalisées et publiées. La présente étude rapporte les principales observations et recommandations de ces études. PMID:24360798

  7. Bacillus licheniformis Contains Two More PerR-Like Proteins in Addition to PerR, Fur, and Zur Orthologues

    PubMed Central

    Ju, Shin-Yeong; Yang, Yoon-Mo; Ryu, Su-Hyun; Kwon, Yumi; Won, Young-Bin; Lee, Yeh-Eun; Youn, Hwan; Lee, Jin-Won

    2016-01-01

    The ferric uptake regulator (Fur) family proteins include sensors of Fe (Fur), Zn (Zur), and peroxide (PerR). Among Fur family proteins, Fur and Zur are ubiquitous in most prokaryotic organisms, whereas PerR exists mainly in Gram positive bacteria as a functional homologue of OxyR. Gram positive bacteria such as Bacillus subtilis, Listeria monocytogenes and Staphylococcus aureus encode three Fur family proteins: Fur, Zur, and PerR. In this study, we identified five Fur family proteins from B. licheniformis: two novel PerR-like proteins (BL00690 and BL00950) in addition to Fur (BL05249), Zur (BL03703), and PerR (BL00075) homologues. Our data indicate that all of the five B. licheniformis Fur homologues contain a structural Zn2+ site composed of four cysteine residues like many other Fur family proteins. Furthermore, we provide evidence that the PerR-like proteins (BL00690 and BL00950) as well as PerRBL (BL00075), but not FurBL (BL05249) and ZurBL (BL03703), can sense H2O2 by histidine oxidation with different sensitivity. We also show that PerR2 (BL00690) has a PerR-like repressor activity for PerR-regulated genes in vivo. Taken together, our results suggest that B. licheniformis contains three PerR subfamily proteins which can sense H2O2 by histidine oxidation not by cysteine oxidation, in addition to Fur and Zur. PMID:27176811

  8. Bacillus licheniformis Contains Two More PerR-Like Proteins in Addition to PerR, Fur, and Zur Orthologues.

    PubMed

    Kim, Jung-Hoon; Ji, Chang-Jun; Ju, Shin-Yeong; Yang, Yoon-Mo; Ryu, Su-Hyun; Kwon, Yumi; Won, Young-Bin; Lee, Yeh-Eun; Youn, Hwan; Lee, Jin-Won

    2016-01-01

    The ferric uptake regulator (Fur) family proteins include sensors of Fe (Fur), Zn (Zur), and peroxide (PerR). Among Fur family proteins, Fur and Zur are ubiquitous in most prokaryotic organisms, whereas PerR exists mainly in Gram positive bacteria as a functional homologue of OxyR. Gram positive bacteria such as Bacillus subtilis, Listeria monocytogenes and Staphylococcus aureus encode three Fur family proteins: Fur, Zur, and PerR. In this study, we identified five Fur family proteins from B. licheniformis: two novel PerR-like proteins (BL00690 and BL00950) in addition to Fur (BL05249), Zur (BL03703), and PerR (BL00075) homologues. Our data indicate that all of the five B. licheniformis Fur homologues contain a structural Zn2+ site composed of four cysteine residues like many other Fur family proteins. Furthermore, we provide evidence that the PerR-like proteins (BL00690 and BL00950) as well as PerRBL (BL00075), but not FurBL (BL05249) and ZurBL (BL03703), can sense H2O2 by histidine oxidation with different sensitivity. We also show that PerR2 (BL00690) has a PerR-like repressor activity for PerR-regulated genes in vivo. Taken together, our results suggest that B. licheniformis contains three PerR subfamily proteins which can sense H2O2 by histidine oxidation not by cysteine oxidation, in addition to Fur and Zur.

  9. Effiziente Verfahren zur Parallelisierung von EMV-Simulationen für den Entwurfsprozess integrierter Schaltungen

    NASA Astrophysics Data System (ADS)

    Barke, M.; Preisner, T.; Mathis, W.

    2009-05-01

    In dieser Arbeit wird mit einer parallelisierten Version des PCG-Verfahrens (preconditioned conjugate gradient method) eine effiziente Technik zur numerischen Lösung großer Gleichungssysteme vorgestellt. Der Anwendungsbereich ist dabei die Simulation numerischer Feldberechnungen (beispielsweise durch die Finite-Elemente-Methode). Es wird ferner auf eine Datenstruktur eingegangen, die für die spezielle Struktur der auftretenden Koeffizientenmatrizen geeignet ist.

  10. Charakterisierung von CMOS RF Blöcken mittels Volterra-Reihen zur Optimierung des Designprozesses

    NASA Astrophysics Data System (ADS)

    Fei, B.; Darrat, A. H.; Mathis, W.

    2009-05-01

    Im Rahmen dieser Arbeit werden die Volterra-Reihen zur Analyse der Nichtlinearität in RF Schaltungen verwendet, um den Designprozess für RF Systeme zu optimieren. Die auf Volterra-Reihen basierende Nichtlinearitätsanalyse wurde in eine Matlab-Toolbox implementiert. Diese Toolbox kann mittels Volterra-Reihen die symbolische Berechnung der Nichtlinearitätsparameter (harmonische Verzerrungen und Intermodulationsverzerrungen) eines RF Blocks für eine gegebene Architektur und Technologie durchführen. Danach können die symbolische Ausdrücke der Nichtlinearitätsparameter in Abhängigkeit von den Architekturparametern und Technologieparametern erhalten werden. Dies ermöglicht die Beschränkung der Wertebereiche der Architekturparameter und die Überprüfung auf die Erfüllung der Nichtlinearitätsspezifikationen für unterschiedliche Kombinationen von Architekturen und Technologien. Somit ist eine Beschränkung der Klassen der Architekturen und Technologien möglich. Die Toolbox wurde zur Verdeutlichung auf einen Low Noise Amplifier (LNA) der Inductive Source Degeneration (ISD) Architektur angewandt. Zur Verifikation wurde diese LNA-Schaltung auch in Cadence SpectreRF Design Tool simuliert.

  11. Combustible caramel pour reacteurs de recherche: Experience acquise en fabrication, controles et irradiation du coeur d'osiris

    NASA Astrophysics Data System (ADS)

    de Contenson, Ghislain; Foulquier, Henri; Trotabas, Maria; Vignesoult, Nicole; Cerles, Jean-Marie; Delafosse, Jacques

    1982-04-01

    L'un des aboutissements des différentes actions menées en France concernant la conception, la fabrication et le développement des combustibles nucléaires a été la mise au point par le CEA d'un combustible de type plaque (combustible CARAMEL) susceptible d'être adapté a différentes catégories de réacteurs à eau (réacteur de puissance, propulsion navale, chauffage urbain, pile de recherche). Ces travaux ont été couronnés par la réalisation de tout un coeur et des recharges du réacteur de recherche à hautes performances, Osiris, à Saclay. L'ancien combustible en alliage U Al fortement enrichi a eté remplacé par un combustible caramel de faible enrichissement (7%), non proliférant. Ce nouveau coeur fonctionne avec satisfaction, depuis janvier 1980. Après une brève description des caractéristiques du combustible caramel et de ses principaux avantages, on présente sa fabrication ainsi que l'ensemble des contrôles de qualité auxquels il est soumis. Le programme de qualification ainsi que les principaux résultáts qui en ont été tirés sont exposés. On décrit également le programme de suivi du combustible en pile dont le but est de s'assurer du bon comportement du combustible sous irradiation. Le bon fonctionnement d'Osiris, qui a terminé 11 cycles d'irradiation le 21 avril 1981, a permis de montrer le bien fondé des choix effectués et l'excellent comportement de l'élément combustible dans les conditions pourtant sévères d'un réacteur de recherche à hautes performances.

  12. Biomedical research in Quebec: the history of the Fonds de la recherche en santé du Québec.

    PubMed Central

    Genest, J

    1996-01-01

    The author describes the history of the Fonds de la recherche en santé du Québec, from after World War II to the present day. The Conseil de la recherche médicale du Québec (Quebec Medical Research Council) was created in 1964 to bring Quebec up to speed in biomedical research through programs that complemented those of the Medical Research Council of Canada. The council progressively evolved, becoming the Conseil de la recherche en santé du Québec (Quebec Health Research Council) in 1974 and the Fonds de la recherche en santé du Québec (FRSQ) in 1982. The FRSQ covers all aspects of medical research, in its broadest sense. Quebec's progress in biomedical research has been spectacular and has had direct and considerable influence on the quality of medical education and patient care. From 1982 to 1996, various Quebec governments have devoted more than +500 million to the FRSQ, a testimony to their comprehension of the importance of this area and to their farsightedness. The FRSQ and its predecessor organizations have been a major force in improving and maintaining the quality of medical teaching and care in Quebec during the last three decades. PMID:8823209

  13. Beitraege zur Astronomiegeschichte, Band 5 (Acta Historica Astronomiae Vol. 18)

    NASA Astrophysics Data System (ADS)

    Duerbeck, H. W.; Dick, W. R.; Hamel, J.

    2003-01-01

    The 18th volume of the Acta Historica Astronomiae is at the same time the sixth collection of essays on the history of astronomy ("Beitræge zur Astronomiegeschichte, Band 6"), edited by the historians of astronomy W.R. Dick (Potsdam) and J. Hamel (Berlin). Besides a few short notices and book reviews, the book contains eight major articles, which deal with astronomical topics covering the time from the 16th to the 19th centuries. The first article by Michael Weichenhan (Berlin) deals with "the invention of the disk-shaped earth: a chapter of Copernican apologetics". The author shows that the concept of a "disc-shaped Earth" was by no means widespread in the middle ages, but restricted to the father of the church Lactantius and some adherents. Nevertheless, it was used by adherents of Copernicus to show the absurd consequences of a strictly literal biblical interpretation -- here concerning the Earth's shape, disc versus sphere, there the geocentric versus the heliocentric system. This thorough philosophical study is followed by two very short articles. "The measuring accuracy of Tycho's large sextant" by Johann Wünsch investigates O-C values of planet-star distances, as based on Tycho's observations as published in the Historia Coelestis (a compilation, which is also based on Tycho's manuscripts, and published in Regensburg in 1672). The result is that standard deviations are 80 arcseconds for Saturn and 89 arcseconds for Jupiter and Mars, an unexpectedly poor result in view of the general opinion that Tycho was famous for his precision work. "The astronomer Christoph Grienberger and the Galilei trial" by Franz Daxecker deals with a Jesuit astronomer who was both the disciple and successor of the mathematician-astronomer Christopher Clavius at the Collegium Romanum. While he was inclined to Galilei early on, he was forced to propagate Aristotelian doctrine. The brief article is very concise, but extremely tiresome to read (3 pages of pure text are embellished by

  14. Probabilistisches Belegtheitsfilter zur Schätzung dynamischer Umgebungen unter Verwendung multipler Bewegungsmodelle

    NASA Astrophysics Data System (ADS)

    Brechtel, Sebastian; Gindele, Tobias; Vogelgesang, Jan; Dillmann, Rüdiger

    In dieser Arbeit wird eine Erweiterung des zeilbasierten Belegtheitsfilters BOFUM1 um Objektgruppen zum BOFUG (Bayesian Occupancy Filtering using Groups) vorgenommen. Diese ermöglicht die Einteilung und Klassifikation der Gruppenzugehörigkeit von Belegtheit, allein auf Basis von statischen Belegtheitsmessungen. Exemplarisch wird für Fußgänger und Fahrzeuge gezeigt, dass die Definition unterschiedlicher Dynamikmodelle ausreicht, um auf Objektinformationen zu schließen und das Filterergebnis nachhaltig zu verbessern. Die implizite Gruppeninferenz stellt einen ersten Schritt zur Vereinigung von Objekt- und Zellebene dar.

  15. La stimulation magnétique transcrânienne (SMT) dans la recherche fondamentale et clinique en neuroscience

    PubMed Central

    Valero-Cabré, Antoni; Pascual-Leone, Alvaro; Coubard, Olivier A.

    2011-01-01

    Introduction Les méthodes de stimulation cérébrale non invasives telles que la Stimulation Magnétique Transcrânienne (SMT) sont largement utilisées pour établir des inférences causales sur les relations entre cerveau et comportement. Des applications cliniques basées sur la SMT ont également été développées pour traiter des affections neurologiques ou psychiatriques comme la dépression, la dystonie, la douleur, les acouphènes ou les séquelles d’accident vasculaire cérébral. État des connaissances La SMT fonctionne en induisant de manière non invasive et de manière focale des courants électriques dans des régions corticales, modulant ainsi leur niveau d’activité de façon variable suivant la fréquence, le nombre d’impulsions, les intervalles et la durée de stimulation utilisés. S’agissant du cortex moteur, on sait par exemple que les patterns d’impulsions de SMT à basse fréquence ou ceux délivrées de manière continue tendent à déprimer l’activité locale, tandis que la SMT à haute fréquence et discontinus tend à la potentialiser. Outre ses effets locaux, la SMT peut aussi avoir des effets à distance sur les régions cérébrales, véhiculés par les connections anatomiques et qui dépendent de l’efficacité et du signe de ces connexions. Perspectives Dans le domaine de la recherche fondamentale et des applications thérapeutiques, l’utilisation efficace de la SMT requiert, cependant, la compréhension approfondie de ses principes opérationnels, de ses risques, de ses potentialités et de ses limites. Dans cet article, nous présentons les principes par lesquels opèrent les méthodes de stimulation cérébrale non invasive, et en particulier la SMT. Conclusion À l’issue de sa lecture, le lecteur sera en mesure de discuter de façon critique les études scientifiques et cliniques utilisant la SMT, ainsi que de concevoir des applications SMT suivant une hypothèse a priori dans le domaine de la recherche en

  16. Le défi de la recherche sur les médicaments et du traitement des enfants au Canada

    PubMed Central

    Rieder, Michael J

    2011-01-01

    RÉSUMÉ Les enfants ont toujours été des « orphelins thérapeutiques ». De nombreux médicaments n’ont pas fait l’objet d’études auprès des enfants et des adolescents ou leur utilisation n’est pas autorisée officiellement auprès d’eux, ce qui crée un défi constant en matière d’élaboration et de définition de pharmacothérapies à la sécurité et l’efficacité optimales au sein du groupe d’âge pédiatrique. Depuis dix ans, des réseaux ont germé aux États-Unis et en Europe afin d’accroître la recherche sur les médicaments dans ce groupe, mais aucune évolution comparable ne s’observe au Canada. Le présent document de principes expose le contexte de la situation canadienne et contient des recommandations qui tiennent compte de deux besoins pressants : plus de recherches sur les médicaments axées sur les enfants et les adolescents canadiens, y compris un financement dédié à de telles recherches, et plus d’effectifs pour mener des études ciblées. Ces initiatives devraient être entreprises en collaboration, sur les scènes nationale et internationale, et inclure des démarches stratégiques et novatrices afin de régler les problèmes et enjeux éthiques uniques que présente la recherche sur les médicaments au sein de cette population.

  17. Von neuen Geschäftsideen zur gelebten Digitalisierung in Utility 4.0 - das Integrierte Geschäftsmodell

    NASA Astrophysics Data System (ADS)

    Doleski, Oliver D.

    Die Energiewirtschaft benötigt neue, digitale Geschäftsmodelle. Gegenwärtig folgt auf Liberalisierung und Energiewende die nächste Stufe einer weitreichenden Bereinigung des Versorgungsmarktes. Digitalisierung und Dezentralisierung sind heute in aller Munde und verlangen nach neuen Produkten und Dienstleistungen. Dabei wirken die immensen Herausforderungen einer digitalen Energiewelt wie Beschleuniger für die Transformation im Versorgungssektor und tragen damit zur breiten Etablierung von Utilities 4.0 bei. Dieser Entwicklungsprozess vollzieht sich mithilfe unterschiedlicher Methoden zur Realisierung neuer Geschäftsideen. Allerdings greifen die gängigen Konzepte zur Entwicklung von Geschäftsmodellen gerade im Hinblick auf die Berücksichtigung komplexer, unbeständiger Rahmenbedingungen und spezifischer Anforderungen der digitalen Energiewelt mitunter zu kurz. Vor diesem Hintergrund wird das auf dem ganzheitlichen St. Galler Management-Konzept beruhende Integrierte Geschäftsmodell iOcTen als geeignetes Instrumentarium zur Geschäftsmodellentwicklung vorgestellt. Neben der Modellbeschreibung unterstützt ein intuitiv verständlicher Leitfaden den Praktiker bei der Transformation vom klassischen Versorgungsunternehmen zum digitalen Energiedienstleistungsunternehmen.

  18. Molekulare Methoden zum Nachweis, zur Quantifizierung und zum Monitoring der Mykotoxinbildung lebensmittelrelevanter Pilze

    NASA Astrophysics Data System (ADS)

    Geisen, Rolf

    Schimmelpilze kommen ubiquitär vor und spielen besonders bei pflanzlichen Lebensmitteln und Rohprodukten eine besondere Rolle als Verderbsorganismen. Es wird geschätzt, dass 20-25 % der jährlichen Produktion an pflanzlichen Produkten durch Schimmelpilze verdorben werden (Smith et al., 1994). Viele der lebensmittelrelevanten Schimmelpilze sind zudem in der Lage, Mykotoxine, toxische Sekundärmetabolite, zu bilden, was das Ausmaß des Problems deutlich macht. Die wichtigsten mykotoxinbildenden Spezies gehören zu den Fusarien (Trichothecene, Fumonisine, Zearalenon), Aspergillen (Aflatoxin, Ochratoxin, Cyclopiazonsäure) und Penicillien (Patulin, Ochratoxin). Für viele Mykotoxine, wie die Aflatoxine, Ochratoxin, Fumonisine und Trichothecene sind Grenzwerte erlassen worden, die die Verkehrsfähigkeit betroffener Produkte regeln. Die Einhaltung der Grenzwerte kann sehr genau durch offizielle chemisch-analytische Methoden, wie HPLC, GC-MS etc. kontrolliert werden. Diese analytischen Methoden sind aber für die Anwendung eines HACCP-Ansatzes zur Kontrolle der Mykotoxinbildung nur bedingt geeignet, da sie Endpunktkontrollen darstellen und nur das über eine längere Zeit gebildete Mykotoxin bestimmen. Sie sagen daher nichts über die biologischen Bedingungen zur Zeit der Bildung durch den Pilz aus.

  19. Identifikationsverfahren zur Analyse von EEG-Signalen bei Epilepsie mit Reaktions-Diffusions Netzwerken

    NASA Astrophysics Data System (ADS)

    Gollas, F.; Tetzlaff, R.

    2007-06-01

    Partielle Differentialgleichungen des Reaktions-Diffusions-Typs beschreiben Phänomene wie Musterbildung, nichtlineare Wellenausbreitung und deterministisches Chaos und werden oft zur Untersuchung komplexer Vorgänge auf den Gebieten der Biologie, Chemie und Physik herangezogen. Zellulare Nichtlineare Netzwerke (CNN) sind eine räumliche Anordnung vergleichsweise einfacher dynamischer Systeme, die eine lokale Kopplung untereinander aufweisen. Durch eine Diskretisierung der Ortsvariablen können Reaktions-Diffusions-Gleichungen häufig auf CNN mit nichtlinearen Gewichtsfunktionen abgebildet werden. Die resultierenden Reaktions-Diffusions-CNN (RD-CNN) weisen dann in ihrer Dynamik näherungsweise gleiches Verhalten wie die zugrunde gelegten Reaktions-Diffusions-Systeme auf. Werden RD-CNN zur Identifikation neuronaler Strukturen anhand von EEG-Signalen herangezogen, so besteht die Möglichkeit festzustellen, ob das gefundene Netzwerk lokale Aktivität aufweist. Die von Chua eingeführte Theorie der lokalen Aktivität Chua (1998); Dogaru und Chua (1998) liefert eine notwendige Bedingung für das Auftreten von emergentem Verhalten in zellularen Netzwerken. Änderungen in den Parametern bestimmter RD-CNN könnten auf bevorstehende epileptische Anfälle hinweisen. In diesem Beitrag steht die Identifikation neuronaler Strukturen anhand von EEG-Signalen durch Reaktions-Diffusions-Netzwerke im Vordergrund der dargestellten Untersuchungen. In der Ergebnisdiskussion wird insbesondere auch die Frage nach einer geeigneten Netzwerkstruktur mit minimaler Komplexität behandelt.

  20. Éthique de la recherche en santé mondiale : la relation Nord-Sud, quel partenariat pour quelle justice sociale ?

    PubMed

    Godard, Béatrice; Hunt, Matthew; Moube, Zéphirin

    2014-06-01

    La recherche en santé mondiale s'inscrit dans une volonté de mobiliser des connaissances au service d'interventions et de politiques publiques pour l'atteinte équitable du bien-être commun, notamment en matière de santé. Elle joue un rôle primordial en ce sens, en favorisant l'implication des communautés et leur autonomisation et de nombreuses lignes directrices supportent un tel partenariat. Néanmoins, certains enjeux éthiques sont liés au financement de la recherche, aux environnements de recherche, à la priorisation des problématiques de recherche, aux mécanismes d'évaluation éthique posent souvent un problème de justice sociale au niveau de la redistribution des ressources et de la reconnaissance des différences culturelles. Comment alors déterminer quelle est la façon « idéale » d'agir en tenant compte de la globalité des individus et du pluralisme culturel des sociétés pour « bien faire », pour satisfaire l'exigence de l'équité? Une réflexion et une démarche éthique demeurent essentielles, ainsi qu'un dialogue entre les chercheurs du Nord et du Sud, et leurs autres partenaires que sont les décideurs, les responsables locaux et les communautés. Un tel dialogue, établi dans un continuum du développement de projets de recherche à leur pérennité, peut grandement contribuer à limiter les problèmes de justice sociale et à viser un développement plus égalitaire des savoirs scientifiques. Plusieurs chercheurs se sont déjà engagés dans cette voie, et leurs initiatives devraient être encouragées pour mettre les nouveaux savoirs au service des populations.

  1. Analysis of the Caulobacter crescentus Zur regulon reveals novel insights in zinc acquisition by TonB-dependent outer membrane proteins.

    PubMed

    Mazzon, Ricardo Ruiz; Braz, Vânia Santos; da Silva Neto, José Freire; do Valle Marques, Marilis

    2014-08-28

    Intracellular zinc concentration needs to be maintained within strict limits due to its toxicity at high levels, and this is achieved by a finely regulated balance between uptake and efflux. Many bacteria use the Zinc Uptake Regulator Zur to orchestrate zinc homeostasis, but little is known regarding the transport of this metal across the bacterial outer membrane. In this work we determined the Caulobacter crescentus Zur regulon by global transcriptional and in silico analyses. Among the genes directly repressed by Zur in response to zinc availability are those encoding a putative high affinity ABC uptake system (znuGHI), three TonB-dependent receptors (znuK, znuL and znuM) and one new putative transporter of a family not yet characterized (zrpW). Zur is also directly involved in the activation of a RND and a P-type ATPase efflux systems, as revealed by β-galactosidase and site-directed mutagenesis assays. Several genes belonging to the Fur regulon were also downregulated in the zur mutant, suggesting a putative cross-talk between Zur and Fur regulatory networks. Interestingly, a phenotypic analysis of the znuK and znuL mutants has shown that these genes are essential for growth under zinc starvation, suggesting that C. crescentus uses these TonB-dependent outer membrane transporters as key zinc scavenging systems. The characterization of the C. crescentus Zur regulon showed that this regulator coordinates not only uptake, but also the extrusion of zinc. The uptake of zinc by C. crescentus in conditions of scarcity of this metal is highly dependent on TonB-dependent receptors, and the extrusion is mediated by an RND and P-type ATPase transport systems. The absence of Zur causes a disturbance in the dynamic equilibrium of zinc intracellular concentration, which in turn can interfere with other regulatory networks as seen for the Fur regulon.

  2. La recherche de naines brunes autour d'etoiles du voisinage solaire et le spectrographe multi-objets SIMON

    NASA Astrophysics Data System (ADS)

    Albert, Loic

    Cette thèse comporte un volet d'instrumentation astronomique, le spectrographe infrarouge SIMON, et un volet de recherche, la recherche de naines brunes autour d'étoiles (lu voisinage solaire. Le premier volet fait état de la construction du Spectrographe infrarouge de Montréal (SIMON), un instrument polyvalent fonctionnant dans le proche infrarouge (0.8-2.5 [mu]m) conçu pour être utilisé à l'Observatoire du mont Mégantic (OMM) et au télescope Canada-France-Hawaii (TCFH). SIMON regroupe plusieurs fonctionnalités: l'irnagerie, la spectroscopie, la spectroscopie rnulti-objets et la polarimétrie. Comme imageur, il offre un champ de vue (le 7.7'x 7.7' à l'OMM et 3.3' x 3.3' au TCFH et possède huit filtres dont un filtre I . SIMON compte trois disperseurs pour la spectroscopie: (1) un prisme d'Amici R max [approximate]50, 0.8-2.5 [mu]m); (2) un grism de silice (R max [approximate]750, 1.17-2.34 [mu]m); et un grism de KRS-5 (R max [approximate]3000, bande J,H ou K S ). Le mode spectroscopique multi-objets utilise des masques cryogéniques placés dans un second cryostat et, couplé au prisme d'Amici, permet l'obtention d'une centaine de spectres simultanément. Le mode polarimétrique permet l'observation de quatre vecteurs de polarisation simultanément. Cette première moitié de thèse étaye les objectifs scientifiques, détaille la conception optique (collimatrice et caméra) et mécanique (un cryostat principal contenant trois cotres à filtres et le détecteur, un cryostat amovible contenant nue roue à masques), décrit l'électronique et le système d'acquisition, et enfin présente les performances dans les différents modes. Le second volet de cette thèse est un relevé grand champ à la recherche de naines brunes de type T autour de 66 étoiles du voisinage solaire. Il a été effectué en utilisant des caméras infrarouges (dont SIMON) et des CCD sur divers télescopes. Le diagramme I--J vs. J--H utilisé est. efficace pour isoler des naines T

  3. Versuche zur Gewinnung von katalytischen Antikörpern zur Hydrolyse von Arylcarbamaten und Arylharnstoffen. (English Title: Attempts to produce catalytic antibodies for hydrolysis of arylcarbamates and arylureas)

    NASA Astrophysics Data System (ADS)

    Werner, Deljana

    2002-05-01

    Im Rahmen dieser Arbeit gelang es, katalytische Antikörper zur Hydrolyse von Benzylphenylcarbamaten sowie zahlreiche monoklonale Antikörper gegen Haptene herzustellen. Es wurden verschiedene Hapten-Protein-Konjugate unter Verwendung unterschiedlicher Kopplungsmethoden hergestellt und charakterisiert. Zur Generierung der hydrolytisch aktiven Antikörper wurden Inzuchtmäuse mit KLH-Konjugaten von 4 Übergangszustandsanaloga (ÜZA) immunisiert. Mit Hilfe der Hybridomtechnik wurden verschiedene monoklonale Antikörper gegen diese ÜZA gewonnen. Dabei wurden sowohl verschiedene Immunisierungsschemata als auch verschiedene Inzuchtmausstämme und Fusionstechniken verwendet. Insgesamt wurden 32 monoklonale Antikörper gegen die verwendeten ÜZA selektiert. Diese Antikörper wurden in groen Mengen hergestellt und gereinigt. Zum Nachweis der Antikörper-vermittelten Katalyse wurden verschiedene Methoden entwickelt und eingesetzt, darunter immunologische Nachweismethoden mit Anti-Substrat- und Anti-Produkt-Antikörpern und eine photometrische Methode mit Dimethylaminozimtaldehyd. Der Nachweis der hydrolytischen Aktivität gelang mit Hilfe eines Enzymsensors, basierend auf immobilisierter Tyrosinase. Die Antikörper N1-BC1-D11, N1-FA7-C4, N1-FA7-D12 und R3-LG2-F9 hydrolysierten die Benzylphenylcarbamate POCc18, POCc19 und Substanz 27. Der Nachweis der hydrolytischen Aktivität dieser Antikörper gelang auch mit Hilfe der HPLC. Der katalytische Antikörper N1-BC1-D11 wurde kinetisch und thermodynamisch untersucht. Es wurde eine Michaelis-Menten-Kinetik mit Km von 210 µM, vmax von 3 mM/min und kcat von 222 min-1 beobachtet. Diese Werte korrelieren mit den Werten der wenigen bekannten Diphenylcarbamat-spaltenden Abzyme. Die Beschleunigungsrate des Antikörpers N1-BC1-D11 betrug 10. Das ÜZA Hei3 hemmte die hydrolytische Aktivität. Dies beweist, dass die Hydrolyse in der Antigenbindungsstelle stattfindet. Weiter wurde zwischen der Antikörperkonzentration und der

  4. Hybridverfahren zur EMV-Analyse elektrischer Leitungen über geschlitztem Grund

    NASA Astrophysics Data System (ADS)

    Ter Haseborg, J. R.; Brüns, H.-D.; Singer, H.

    2006-09-01

    Die Betrachtung niedrig geführter elektrischer Leitungen über leitendem Grund stellt besondere Anforderungen an die numerische Feldanalyse. Insbesondere für Fälle ungleichförmiger Leitungsführung oder ungleichförmigen Grunds werden Verfahren benötigt, die eine effektive EMV-Analyse zulassen. Die Verwendung von volldiskretisierten Modellen erfordert aufwändige Diskretisierungen, große Ressourcen und hohe Rechenzeiten. Daher werden Möglichkeiten gesucht, die effektive Leitungstheorie auf Anordnungen anzuwenden, deren direkte Berechnung in klassischer Betrachtungsweise nicht möglich ist. In der vorliegenden Arbeit wird ein Hybridverfahren vorgestellt, um den Einfluss von Schlitzen unterhalb von Leitungen in einer approximativen EMV-Analyse zu untersuchen. Hierzu dient neben der Leitungstheorie zur Berechnung des Leiterstroms eine momententheoretische Simulation auf Basis von magnetischen Linienströmen.

  5. A Summary of Transonic Natural Laminar Flow Airfoil Development at NAE (Resume Des Recherches de l’Ena sur des Profils Aerodynamiques A Ecoulements Laminaires Naturels Transsoniques)

    DTIC Science & Technology

    1990-05-01

    connaissances. RAPPORTS TECHNIQUES DE LABORATOIRE (LTR): Informations peu dissdmindes pour des raisons d’usage secret, de droit de propn6t ou autres ou parce ...COULEMENTS LAMINAIRES NATURELS TRANSSONIQUES Acce-,iwn For NTIS CRA&I DTIC TAB Urianoonnced 0 Jusficatcn by/par copy B IVSPEc7rE Dislribiution I M. Khalid...r6sultats exp6rimentaux obtenus pour quatre profils a6rodynamiques I 6coulements laminaires naturels surcritiques qui ont fait l’objet de recherches A

  6. La santé des pasteurs mobiles au Sahel - Bilan de 15 années de recherches et développement.

    PubMed

    Montavon, A; Jean-Richard, V; Bechir, M; Daugla, D M; Abdoulaye, M; Bongo Naré, R N; Diguimbaye-Djaibé, C; Alfaroukh, I O; Schelling, E; Wyss, K; Tanner, M; Zinsstag, J

    2013-09-01

    Dans le Sahel, entre la Mauritanie et la Somalie incluant le Nord Kenya, environ 20 à 30 millions de personnes vivent en transhumance. Le rythme de leur migration suit l'évolution saisonnière du climat et la disponibilité des ressources, telle que l'eau, le pâturage et le sel. Malgré une exposition élevée à certaines maladies comme les zoonoses et les problèmes conditionnés liés au climat, les pasteurs mobiles sont parmi les populations quasiment exclues du système de santé, car la mise à disposition des services sociaux adaptés à un mode de vie mobile est difficile. Suivant l'objectif de recherche d'un meilleur accès aux soins des pasteurs mobiles, l'Institut Tropical et de Santé Publique Suisse, en partenariat avec plusieurs institutions dans la région, est actif au Sahel depuis 15 ans, aussi bien dans le domaine de la recherche, que celui des actions de développement. Basées sur une approche orientée vers les besoins des pasteurs mobiles pour leur développement, des recherches interdisciplinaires ont contribué à mieux comprendre la situation et les problèmes des éleveurs. En relation de la proximité entre l'homme et son bétail, une approche unissant la santé humaine et animale s'est avérée bonne et la valeur ajoutée d'une meilleure collaboration entre médecine humaine, animale et l'environnement a été démontrée. Ces approches utiles devraient être poursuivies et consolidées dans les recherches et le développement des actions futurs. © 2013 The Authors. Tropical Medicine and International Health published by John Wiley & Sons Ltd.

  7. [Utilization of the results or research about nursing workload in a surgical suite, based on the methodology of the "Projet de Recherche en Nursing" (PRN87)].

    PubMed

    Alvaro, Rosaria; Venturini, Giulia; Roberto, Roberta

    2006-01-01

    The aim of this study was to evaluate actual levels of nursing care delivered in a functionally aggregated Surgery Area of the Tor Vergata University Hospital in Rome, by measuring nursing workload according to the "Projet de Recherche en Nursing" (PRN87) methodology. The study was performed between February 1st and June 26, 2004. The results of the study have highlighted the fact that nursing staff is often improperly used, for example to perform many administrative activities, thereby reducing the quality and amount of direct nursing care.

  8. Vergleich von rekombinanten Vaccinia- und DNA-Vektoren zur Tumorimmuntherapie im C57BL/6-Mausmodell

    NASA Astrophysics Data System (ADS)

    Johnen, Heiko

    2002-10-01

    In der vorliegenden Arbeit wurden Tumorimpfstoffe auf der Basis des Plasmid-Vektors pCI, modified vaccinia virus Ankara (MVA) und MVA-infizierten dendritischen Zellen entwickelt und durch Sequenzierung, Western blotting und durchflußzytometrische Analyse überprüft. Die in vivo Wirksamkeit der Vakzinen wurde in verschiedenen Tumormodellen in C57BL/6 Mäusen verglichen. Die auf dem eukaryotischen Expressionsvektor pCI basierende DNA-Vakzinierung induzierte einen sehr wirksamen, antigenspezifischen und langfristigen Schutz vor Muzin, CEA oder beta-Galactosidase exprimierenden Tumoren. Eine MVA-Vakzinierung bietet in den in dieser Arbeit durchgeführten Tumormodellen keinen signifikanten Schutz vor Muzin oder beta-Galactosidase exprimierenden Tumoren. Sowohl humane, als auch murine in vitro generierte dendritische Zellen lassen sich mit MVA – im Vergleich zu anderen viralen Vektoren – sehr gut infizieren. Die Expressionsrate der eingefügten Gene ist aber gering im Vergleich zur Expression in permissiven Wirtszellen des Virus (embryonale Hühnerfibroblasten). Es konnte gezeigt werden, daß eine MVA-Infektion dendritischer Zellen ähnliche Auswirkungen auf den Reifezustand humaner und muriner dendritischer Zellen hat, wie eine Infektion mit replikationskompetenten Vakzinia-Stämmen, und außerdem die Hochregulation von CD40 während der terminalen Reifung von murinen dendritischen Zellen inhibiert wird. Die während der langfristigen in vitro Kultur auf CEF-Zellen entstandenen Deletionen im MVA Genom führten zu einer starken Attenuierung und dem Verlust einiger Gene, die immunmodulatorische Proteine kodieren, jedoch nicht zu einer Verminderung des zytopathischen Effekts in dendritischen Zellen. Die geringe Expressionsrate und die beobachtete Inhibition der Expression kostimulatorischer Moleküle auf dendritischen Zellen kann für eine wenig effektive Induktion einer Immunantwort in MVA vakzinierten Tieren durch cross priming oder die direkte Infektion

  9. Periodisches Hitzdrahtverfahren zur Messung von Wärme- und Temperaturleitfähigkeit von geringen Stoffmengen

    NASA Astrophysics Data System (ADS)

    Griesinger, A.; Spindler, K.; Hahne, E.

    Zusammenfassung Es wird ein Meßverfahren zur gleichzeitigen Bestimmung der Wärme- und der Temperaturleitfähigkeit von geringen Stoffmengen beschrieben. Neben Messungen an hochviskosen Flüssigkeiten eignet sich das Verfahren besonders für Messungen an Pulver-Schüttungen. Das Meßverfahren basiert auf dem transienten Hitzdraht-Verfahren. In einem dünnen Platindraht fließt ein sinusförmiger Wechselstrom, der den Draht periodisch erwärmt. Es entstehen thermische Wellen, die in die umgebende Probe eindringen. Die Amplitude und die Phasenlage der thermischen Wellen in der Probe hängen von der Temperaturleitfähigkeit a und der Wärmeleitfähigkeit λ der Probe ab. Die Temperaturschwingung in der Probe wird mit Hilfe des Platindrahtes gemessen, der gleichzeitig als Widerstandsthermometer eingesetzt wird. Meßwerte von Wasser und Glycerin zeigen eine gute Übereinstimmung mit Literaturwerten. Das Meßverfahren zeichnet sich dadurch aus, daß zur Bestimmung der Wärme- und Temperaturleitfähigkeit nur 13 ml einer Probe benötigt werden. Es werden Meßwerte einer Zeolith-Schüttung unter Wasserstoffbeladung dargestellt. A measuring procedure for the simultaneous determination of the thermal conductivity and thermal diffusivity of small quantities is described. The procedure is suited for high-viscous fluids and for powdery material. The measuring principle is based on the transient hot-wire method. A sinusoidal alternating current flows through a thin platinum wire and heats up the wire periodically. This results in thermal waves, which penetrate into the surrounding sample. The amplitude and the phase shift of the thermal waves depend on the thermal diffusivity ``a'' and the thermal conductivity ``λ'' of the sample. The temperature oscillation in the sample is measured by means of the platinum wire, which is simultaneously applied as a resistance thermometer. The values measured for water and glycerine correspond well to those given in literature. Results of the

  10. Modellierungskonzept für MOS Varaktoren zur Minimierung der AM-FM Konversion in VCOs

    NASA Astrophysics Data System (ADS)

    Peikert, T.; Bremer, J.-K.; Mathis, W.

    2010-10-01

    In dieser Arbeit wird ein analytisches Simulationsmodell für MOS Varaktoren zur Entwurfsunterstützung von integrierten CMOS LC-Tank VCO-Schaltungen präsentiert. Das analytische Simulationsmodell wurde auf Basis des EKV-Transistormodells implementiert und beinhaltet ausschließlich Design- und Prozessparameter für die Berechnung der Varaktorkapazität. Dieses Simulationsmodell ermöglicht es, die verwendeten Varaktoren im Vorfeld des VCO-Entwurfs zu dimensionieren, die effektive Großsignalkapazität in Abhängigkeit des Ausgangssignals zu berechnen und einzelne Eigenschaften der Varaktoren, wie z.B. das AM-FM Konversionsverhalten zu optimieren. Die Gültigkeit des vorgestellten analytischen Simulationsmodells zur Beschreibung der Varaktorkapazität in CMOS LC-Tank VCOs, wird anhand von Spectre (Cadence) Simulationen auf Basis eines 0.25 μm CMOS Prozesses der Firma IHP (SGB25) und eines 0.35 μm CMOS Prozesses der Firma AMS (C35) verifiziert. In this work an analytical simulation model for MOS varactors, that can be used in a systematically VCO design flow, is presented. The simulation model is based on the EKV transistor model and includes only design and process parameters of the used CMOS technology. The proposed simulation model allows calculating the required design parameters and the effective large signal capacitance of the varactors incorporated into the VCO as a function of the output signal of the VCO. Based on the expression for the effective large signal capacitance it is possible to optimize the AM-FM conversion behavior of the used varactors. The validity and accuracy of the simulation model is verified by Spectre simulations which are based on a 0.25 μm CMOS process (SGB25) from the company IHP and a 0.35 μm CMOS process (C35) from the company AMS. The simulation results show a good accordance in all transistor operating regions for NMOS varactors as well as PMOS varactors.

  11. Methodik zur Zuverlässigkeitsbewertung in frühen Entwicklungsphasen

    NASA Astrophysics Data System (ADS)

    Bertsche, Bernd; Gäng, Jochen

    Im Folgenden soll eine Methodik zur Zuverlässigkeitsbewertung mechatronischer Systeme vorgestellt werden, die in frühen Entwicklungsphasen anwendbar ist. Eine wichtige Anforderung an diese Methodik ist die Verknüpfung an mechatronischen Entwicklungsmethoden, um so die Entwicklungstätigkeiten sowie die Konzeptauswahlentscheidungen zu unterstützen. Dies erlaubt dann das zuverlässigste Konzept auszuwählen. Dadurch können Kosten und Zeit gespart werden, da die Auswahl eines unzuverlässigen Konzepts im Nachhinein viele aufwändige Änderungen bis zu einer Neukonzeption mit sich bringen kann. Für die Auswahl der Entwicklungsmethode bietet sich das V-Modell aus der Richtlinie VDI 2206 [3.44] an (siehe Kap. 2.2). Mit dem Schwerpunkt der frühen Entwicklungsphasen muss besonders die erste Phase des V-Modells, der Systementwurf, näher betrachtet werden. Anhand des Systementwurfes ist eine Vorgehensweise entstanden, die insgesamt sechs Schritte umfasst (Abb. 3.1). Diese sind im Laufe der Förderzeit der Forschergruppe nach und nach erweitert worden. Im Folgenden werden die einzelnen Schritte detailliert beschrieben und erklärt.

  12. [COPD und Klangtherapie: Pilotstudie zur Wirksamkeit einer Behandlung mit Körpertambura bei COPD-Patienten].

    PubMed

    Hartwig, Bernhard; Schmidt, Stefan; Hartwig, Isabella

    2016-01-01

    Hintergrund: Erkrankungen der Atemorgane treten mit steigendem Alter öfter auf, nehmen weltweit zu und sind häufige Ursachen für Morbidität und Mortalität. In dieser Pilotstudie wurde der Frage nachgegangen, ob eine einmalige 10-minütige Behandlung mit einer Körpertambura eine signifikante und effektive Verbesserung der Lungenfunktion von Patienten mit chronisch-obstruktiver Lungenerkrankung (COPD; GOLD-Stadium A oder B) erbringen kann. Patienten und Methoden: 54 Probanden konnten je zur Hälfte in eine Behandlungsgruppe (Körpertambura) und eine aktive Kontrollgruppe (Atemtherapie) randomisiert werden. Eine Bestimmung der Lungenfunktionsmessparameter «Einsekundenkapazität» (FEV1) und «inspiratorische Vitalkapazität» (IVC) zu den Zeitpunkten T1 (Baseline), T2 (direkt nach Behandlung) und als Follow-up etwa 3 Wochen nach T1 (T3). Ergebnisse: Die Behandlungsgruppe zeigte sich der Kontrollgruppe in beiden Werten signifikant überlegen. Die Zeit-×-Gruppe-Interaktion (Varianzanalyse) ergab p = 0,001 (FEV1) bzw. p = 0,04 (IVC). Die Behandlungsgruppe zeigte bei beiden Werten eine Verbesserung von klinischer Relevanz. Schlussfolgerung: Diese Ergebnisse zeigen, dass die Klangbehandlung mittels einer Körpertambura - neben den schulmedizinischen, leitliniengerechten Therapien - eine zusätzliche, nebenwirkungsarme, aber durchaus klinisch wirksame Option für die Behandlung von COPD-Patienten darstellen kann, um deren Lebensqualität zu stabilisieren und zu verbessern. © 2016 S. Karger GmbH, Freiburg.

  13. Ganzheitliche Digitalisierungsansätze im Stadtwerk: Von der Strategie bis zur Umsetzung

    NASA Astrophysics Data System (ADS)

    Dudenhausen, Roman; Hahn, Heike

    Digitalisierung muss im Stadtwerk dazu führen, Kundenerwartungen, die heutzutage schon vielfach durch digitales Know-how und Erfahrungen geprägt sind, in einzigartiger Weise zu entsprechen - in Form digitaler Kundenkontaktpunkte, automatisierter Prozesse oder plattformbasierter Geschäftsmodelle. Eine große Rolle spielen dabei unternehmensweit nutzbare Informationen, die eine 360-Grad-Sicht auf den Kunden ermöglichen. Nur in dieser Kombination werden sich nachhaltig Wettbewerbsvorteile generieren lassen. Manch ein Kunde wird die Lust, einen Prozess zu Ende zu gehen, schon vor dem Abschluss verlieren, wenn er nicht unmittelbar und ohne die digitale Welt zu verlassen zum Ziel kommt. Eine nur "halb digitale Kundenerfahrung" wird weder zu Neugeschäft noch zur positiven emotionalen Bindung zwischen Kunden und Stadtwerk führen. Nicht zu unterschätzen sind zudem Erwartungen hinsichtlich zukünftiger Geschäftsmodelle, aus denen sich disruptive Bedrohungen für die herkömmlichen Strom- und Gasangebote ergeben werden. Erste innovative Ansätze finden sich bereits im Markt, die erahnen lassen, dass zurzeit viel diskutierte Technologien wie die Blockchain nicht mehr nur hypothetischer Natur sind. Die Auseinandersetzung mit der Digitalisierung erfolgt dabei sinnvollerweise in einem unternehmensweit abgestimmten Rahmen, der eine zielgerichtete und ganzheitliche Vorgehensweise ermöglicht.

  14. Einstellung und Wissen von Lehramtsstudierenden zur Evolution - ein Vergleich zwischen Deutschland und der Türkei

    NASA Astrophysics Data System (ADS)

    Graf, Dittmar; Soran, Haluk

    Es wird eine Untersuchung vorgestellt, in der Wissen und Überzeugungen von Lehramtsstudierenden aller Fächer zum Thema Evolution an zwei Universitäten in Deutschland und der Türkei erhoben worden sind. Die Befragung wurde in Dortmund und in Ankara durchgeführt. Es stellte sich heraus, dass ausgeprägte Defizite im Verständnis der Evolutionsmechanismen herrschen. Viele Studierende, insbesondere aus der Türkei, sind nicht von der Faktizität der Evolution überzeugt. Dies gilt sowohl für Studierende mit Fach Biologie als auch für Studierende mit anderen Fächern. Näher untersucht worden sind die Faktoren, die die Überzeugungen zur Evolution beeinflussen können, was ja in Anbetracht der hohen Ablehnungsrate der Evolution von besonderem Interesse ist. Das Vertrauen in die Wissenschaft spielt hierbei eine besondere Rolle: Wer der Wissenschaft vertraut, ist auch eher von der Evolution überzeugt, als diejenigen, die skeptisch gegenüber der Wissenschaft sind.

  15. Re-Imagining "Bildung Zur Humanität": How I Developed the Dialogos Approach to Practical Philosophy through Action Inquiry Research

    ERIC Educational Resources Information Center

    Helskog, Guro Hansen

    2015-01-01

    This paper presents an account of how I developed the Dialogos approach to practical philosophy through action inquiry research. The process of development is understood as a contribution to the reconstruction of the notion "Bildung zur Humanität" as an ideal in education. Core perspectives, traditions and purposes involved in the action…

  16. “&ldots;how the right technique emerged at the right time” Zur Geschichte der fotografischen Methode im Kalten Krieg

    NASA Astrophysics Data System (ADS)

    Fengler, Silke

    Die Frühgeschichte der fotografischen Methode, die als Nachweisinstrument kernphysikalischer und kosmischer Strahlung in den 1950er Jahren zur Blüte kam, hat das Interesse vieler Wissenschaftshistoriker gefunden. Peter Galison hat gezeigt, wie fragil das Experimentalsystem lange Zeit war, das sich um die Methode bildete, und wie prekär die mit ihr aufgezeichneten Ergebnisse.

  17. Re-Imagining "Bildung Zur Humanität": How I Developed the Dialogos Approach to Practical Philosophy through Action Inquiry Research

    ERIC Educational Resources Information Center

    Helskog, Guro Hansen

    2015-01-01

    This paper presents an account of how I developed the Dialogos approach to practical philosophy through action inquiry research. The process of development is understood as a contribution to the reconstruction of the notion "Bildung zur Humanität" as an ideal in education. Core perspectives, traditions and purposes involved in the action…

  18. ["Recherche de la vraye anathomie des dents, nature et propriété d'icelles", the first French dentistry book by the surgeon from Rouergue, Urbain Hémard (Benoist Rigaud, Lyon, 1582].

    PubMed

    Ruel-Kellermann, Micheline

    2010-01-01

    Recherche sur la vraye anathomie des dents, nature & propriété d'icelles (1582) is the last dental book of the 16th century and the first in France. The part borrowed from Libellus de dentibus by Bartolommeo Eustachio is not the most interesting part of the book; the better part is when Hémard tells personal experiences with his picturesque words, showing violent situations of care at this epoch.

  19. Functional definition and global regulation of Zur, a zinc uptake regulator in a Streptococcus suis serotype 2 strain causing streptococcal toxic shock syndrome.

    PubMed

    Feng, Youjun; Li, Ming; Zhang, Huimin; Zheng, Beiwen; Han, Huiming; Wang, Changjun; Yan, Jinghua; Tang, Jiaqi; Gao, George F

    2008-11-01

    Zinc is an essential trace element for all living organisms and plays pivotal roles in various cellular processes. However, an excess of zinc is extremely deleterious to cells. Bacteria have evolved complex machineries (such as efflux/influx systems) to control the concentration at levels appropriate for the maintenance of zinc homeostasis in cells and adaptation to the environment. The Zur (zinc uptake regulator) protein is one of these functional members involved in the precise control of zinc homeostasis. Here we identified a zur homologue designated 310 from Streptococcus suis serotype 2, strain 05ZYH33, a highly invasive isolate causing streptococcal toxic shock syndrome. Biochemical analysis revealed that the protein product of gene 310 exists as a dimer form and carries zinc ions. An isogenic gene replacement mutant of gene 310, the Delta310 mutant, was obtained by homologous recombination. Physiological tests demonstrated that the Delta310 mutant is specifically sensitive to Zn(2+), while functional complementation of the Delta310 mutant can restore its duration capability, suggesting that 310 is a functional member of the Zur family. Two-dimensional electrophoresis indicated that nine proteins in the Delta310 mutant are overexpressed in comparison with those in the wild type. DNA microarray analyses suggested that 121 genes in the Delta310 mutant are affected, of which 72 genes are upregulated and 49 are downregulated. The transcriptome of S. suis serotype 2 with high Zn(2+) concentrations also showed 117 differentially expressed genes, with 71 upregulated and 46 downregulated. Surprisingly, more than 70% of the genes differentially expressed in the Delta310 mutant were the same as those in S. suis serotype 2 that were differentially expressed in response to high Zn(2+) concentration, consistent with the notion that 310 is involved in zinc homeostasis. We thus report for the first time a novel zinc-responsive regulator, Zur, from Streptococcus suis

  20. Book Review: Beitraege zur Astronomiegeschichte, Band 5 (Acta Historica Astronomiae Vol. 15)

    NASA Astrophysics Data System (ADS)

    Duerbeck, H. W.; Dick, W. R.; Hamel, J.

    2002-12-01

    The 15th volume of the Acta Historica Astronomiae is at the same time the fifth collection of essays on the history of astronomy (Beitraege zur Astronomiegeschichte, Band 5), edited by the historians of astronomy W.R. Dick (Potsdam) and J. Hamel (Berlin). Besides a few short notices and book reviews, the book contains 11 major articles, which deal with astronomical topics covering the time from the 16th to the 20th centuries. The first article, on the analysis and interpretation of historical horoscopes as a source of the history of science, is based on the inaugural lecture of its author, Guenther Oestmann. After a general introduction, which deals with the principles of horoscope making, the author discusses the horoscope of Count Heinrich Ranzau (1526-1598), the Danish governor of Schleswig-Holstein, who was a friend of Tycho Brahe. Oestmann shows that the astronomical-mathematical basis of such a horoscope can be reconstructed and interpreted. However, it is hardly possible to gain an insight in the process how the interpretation of a horoscope was done in detail. The second and third articles, by Franz Daxecker, deal with Athanasius Kircher and Christoph Scheiner, two catholic astronomers of the 17th century. Kircher's Organum Mathematicum is a calculating device that can be used in the fields of arithmetic, geometry, chronology, astronomy, astrology and others. The author provides extracts of the description of the Organum taken from a book by Caspar Schott, which deal with chronology and astronomy. A photograph of the Organum indicates that this tool consists of a set of tables glued on wooden or cardboard, but details of its contents and applications remain pretty obscure for the reader - a few elaborated examples would have been helpful. The second paper deals with the life of Christoph Scheiner SJ, the co-discoverer of sunspots (next to Galileo), after leaving Rome in 1633 - the year of the Galileo trial. Scheiner spent his later years in the Austrian and

  1. Modulare und durchgängige Produktmodelle als Erfolgsfaktor zur Bedienung einer Omni-Channel-Architektur - PLM 4.0

    NASA Astrophysics Data System (ADS)

    Golovatchev, Julius; Felsmann, Marcus

    Mit der Transformation der Wertschöpfungsstrukturen von Utility 1.0 zu Utility 4.0 erfolgt offensichtlich auch eine Veränderung des Produkts. Vor dem Hintergrund disruptiver Technologien (IoT, Big Data, Cloud, Robotics etc.) und auch gesellschaftlicher Veränderungen entstehen ständig neue Geschäftsmodelle und Produkte, die über die reine Versorgungsdienstleistung (z. B. Strom) hinausgehen. Dabei muss der wertvolle Rohstoff Produktdaten für smarte Produkte durchgängiger und schneller nutzbar gemacht werden. Die modularen und durchgängigen Produktstrukturen leisten einen Beitrag zur Beherrschung von Komplexität und stellen somit einen wesentlichen Hebel für erfolgreiche Produktentwicklung und -management dar. In diesem Beitrag werden Ansätze beschrieben, wie es den vor der Herausforderung Utility 4.0 stehenden Unternehmen gelingen kann, Smart-Energy-Produkte so zu modellieren, dass sie die Interoperabilität der einzelnen Produktionsmodule sicherstellt und ein Ende-zu-Ende-Management ermöglicht.

  2. Reaktive Tracer zur Bestimmung der sedimentären Aquifer-Oxidationskapazität im Labor- und Feldversuch

    NASA Astrophysics Data System (ADS)

    Dethlefsen, Frank; Bliss, Fabian; Wachter, Thorsten; Dahmke, Andreas

    Kurzfassung Mikrobiell reduzierbares Eisen(III) im Aquifer kann als Elektronenakzeptor von großer Bedeutung für Natural Attenuation (NA) von aromatischen Kohlenwasserstoffen sein und bildet den Hauptbestandteil der sedimentären Oxidationskapazität (OXC) des Aquifers. Untersuchungsgegenstand war der Vergleich traditioneller, nasschemischer Methoden mit neuentwickelten, reaktiven Tracerverfahren zur Bestimmung der sedimentären OXC. Die innovativen Tracermethoden haben gegenüber nasschemischen Extraktionsverfahren den prinzipiellen Vorteil, dass sie einen integralen Ansatz zur Bestimmung der sedimentären OXC bilden, weil geochemische und hydraulische Heterogenitäten des Aquifers berücksichtigt werden. Daher wurden am RETZINA-Standort Zeitz einerseits herkömmliche Säure-Extraktionsmethoden (bestimmter Eisen(III)-Gehalt: 0,43 +/- 0,07 mg/g Aquifermaterial) und andererseits reaktive Tracertests mit Phosphat-(Eisen(III): 1,0 mg/g) und Sulfidtracern (Eisen(III): 0,31 +/- 0,02 mg/g) in Laborversuchen sowie Bioabbauversuche mit Toluol als Kohlenstoffquelle undGeobacter metallireducensals Eisen(III)-Reduzierer (Eisen(III): 1,0 mg/g) durchgeführt. Sulfid als reaktiver Tracer wurde in Form eines 〝Push-Pull-Tests`` im Feldversuch eingesetzt (Eisen(III): 1,1 mg/g). Zudem bedeutet die Anwendung des Feld-Tracerverfahrens deutlich weniger Zeitaufwand in der Durchführung als die Anwendung traditioneller Extraktionsmethoden. Microbially reducible iron(III) is important as a terminal electron acceptor for the Natural Attenuation (NA) of aromatic hydrocarbons and forms the balance of the aquifer's sedimentary oxidation capacity (OXC). It was the aim of this investigation to compare traditional acid extraction methods to reactive tracer methods in quantifying the sedimentary OXC. The sedimentary OXC at the RETZINA test site in Zeitz was therefore determined through traditional acid extraction methods (determined Iron(III)-content: 0.43 +/- 0.07 mg/g aquifer material) and

  3. Low risk of nevirapine resistance mutations in the prevention of mother-to-child transmission of HIV-1: Agence Nationale de Recherches sur le SIDA Ditrame Plus, Abidjan, Cote d'Ivoire.

    PubMed

    Chaix, Marie-Laure; Ekouevi, Didier Koumavi; Rouet, Francois; Tonwe-Gold, Besigin; Viho, Ida; Bequet, Laurence; Peytavin, Gilles; Toure, Hassane; Menan, Herve; Leroy, Valeriane; Dabis, Francois; Rouzioux, Christine

    2006-02-15

    The frequency of resistance mutations was estimated in the cohort of Agence Nationale de Recherches sur le SIDA Ditrame Plus, a study that evaluated the combination of short-course zidovudine (ZDV) plus lamivudine (3TC) and single-dose nevirapine (SD-NVP) followed by 3 days of postpartum ZDV plus 3TC for the prevention of mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1). The frequency with which resistance mutations were detected in mothers at week 4 postpartum was 1.14% (95% confidence interval [CI], 0.03%-6.17%) for NVP and 8.33% (95% CI, 3.66%-15.76%) for 3TC. In multivariate analysis, 3TC resistance was associated with a longer duration of ZDV plus 3TC prepartum prophylaxis (P=.009). This regimen, which is feasible in resource-limited settings, prevents most peripartum HIV-1 transmission and minimizes the development of NVP resistance.

  4. Das Blüte-Bestäuber-Netz auf Brachflächen : biozönologische Untersuchung zur Bedeutung von Brachen in einer intensiv genutzten Agrarlandschaft

    NASA Astrophysics Data System (ADS)

    Hahn, Robert

    2002-11-01

    In der vorliegenden Dissertation wird die Bedeutung von Brachen für Artenvielfalt und Stabilität von Blüte-Bestäuber-Nahrungsnetzen in agrarisch genutzten Landschaften anhand ausgewählter blütenbesuchender Insektengruppen (Syrphidae, Lepidoptera) untersucht. Die Freilandarbeiten fanden von 1998-2000 im Raum der Feldberger Seenlandschaft, Mecklenburg-Vorpommern, statt. Es werden die beiden Hauptnahrungsquellen Nektar und Pollen betrachtet, dabei fanden Untersuchungen zur Intensität der Blüte-Bestäuber-Interaktion auf Stilllegungsflächen, zum flächenbezogenen quantitativen Nektarangebot im Jahresverlauf, zur individuellen Pollennutzung bei Syrphiden und zur Breite und Überlappung der Nahrungsnischen bei den dominanten Arten Episyrphus balteatus, Metasyrphus corollae, Syritta pipiens und Sphaerophoria scripta statt. Im Ergebnis zeigt sich eine hohe Bedeutung der Brachflächen für die Stabilität des Blüte-Bestäuber-Netzes, während die Diversität von anderen, eher landschaftsbezogenen Faktoren abhängig ist. This dissertation examines the importance of fallow land for the diversity and stability of pollination webs in agricultural landscapes as exemplified by selected groups of anthophilous insects (syrphidae and lepidoptera). The field studies were carried out between 1998 and 2000 in the Feldberg lakeland area in the north-east German State of Mecklenburg-Western Pomerania. Observations were made of nectar and pollen as the two main sources of food. Studies were conducted into the intensity of plant-pollinator interaction in set-aside areas, the site-specific quantity of nectar available during the vegetation period and the individual pollen intake of syrphid flies. Different methods were employed to establish the breadth of the trophic niches among the predominant species (Episyrphus balteatus, Metasyrphus corollae, Syritta pipiens and Sphaerophoria scripta) and the extent to which they overlapped. The studies showed that, while fallow land is very

  5. [Assessment of parental stress using the "Eltern-Belastungs-Screening zur Kindeswohlgefährdung" (EBSK) - association with emotional and behavioral problems in children].

    PubMed

    Eichler, Anna K; Glaubitz, Katharina A; Hartmann, Luisa C; Spangler, Gottfried

    2014-07-01

    Parental stress is increased in clinical contexts (e.g., child psychiatry) and correlates with behavioral and emotional problems of children. In addition, parental stress can result in a biased parental perception of child's behavior and emotions. These interrelations were examined in a normal (N = 320) and a clinical (N = 75) sample. The "Eltern-Belastungs-Screening zur Kindeswohlgefährdung" (EBSK; Deegener, Spangler, Körner & Becker, 2009) was used for the assessment of parental stress. As expected, increased EBSK scores were overrepresented in the clinical sample. In both samples stressed parents reported having children with more behavioral and emotional problems. Children of stressed parents in turn reported significantly less problems than their parents did. The rating of independent third persons, e.g. teachers, was not available and should be added in future research. Restrictions in methodology and conclusions for practice are discussed.

  6. Variabilität des Reviergesangs des Buchfinken (Fringilla coelebs) zur Raum-Zeit-Beschreibung von Metapopulationen

    NASA Astrophysics Data System (ADS)

    Nolte, Björn

    2003-10-01

    Der Buchfinkengesang wurde in Potsdam in zwei Hauptpopulationen über drei Jahre aufgenommen. Jedes Individuum wurde eindeutig am individuellen Strophentypenrepertoire identifiziert. Ein weiterer Punkt der die individuelle Wiedererkennung bestätigt ist die hohe Standorttreue der adulten Männchen. Die beschriebene Methode eignet sich für die Untersuchung von gesamten Populationen, um den Wandel des Gesangs von Populationen in Raum und Zeit zu beschreiben. Die Haupterkenntnisse der Arbeit sind: - Die Gesamtanzahl der Grundstrophentypen innerhalb einer Population bleibt über Jahre konstant. - Die relative Häufigkeit jedes einzelnen Strophentyps variiert von Jahr zu Jahr und von Population zu Population. - Gesangslernen erfolgt exakt mit einem Korrektheitsgrad von mindestens 96%. - Das Song-Sharing ist innerhalb der Population hoch. Die diskutierten Mechanismen für das Song-Sharing sind: Die Lebenserwartung, das Zugverhalten, das Lernverhalten, die Etabliertheit von Strophentypen, Weibchenpräferenzen und die Reaktionen der territorialen Männchen. - Weiterhin wurde ein Modell zur kulturellen Evolution des Buchfinkengesangs programmiert, um die Rolle der Einflussfaktoren, wie Fehlerquote, Abwanderungsrate und Laufzeit zu ermitteln. Der Wandel des Dialektes erfolgt graduell in Raum und Zeit. Daher sind keine scharfen Dialektgrenzen anzutreffen. Trotz dieser Tatsache markieren die etablierten Strophentypen die Population. 50 % der Juvenilen siedeln am Geburtsort, auf diese Weise bleibt der Dialekt erhalten und Inzest wird vermieden. -Analysiert man das Repertoire benachbarten Männchen bei isolierten Alleen, so entspricht die Gesangsangleichung in etwa dem Zufall. -Intraindividuelle Vergleiche der quantitativen Parameter des jeweiligen Strophentyps wurden saisonal und annuell durchgeführt. Saisonal konnten für einen Strophentyp ein Trend ermittelt werden. Bei jährlichen Vergleichen konnten intraindividuell ausschließlich nicht signifikante Ergebnisse ermittelt

  7. Developpement de competences de resolution reflexive de problemes environnementaux aupres d'enseignants en formation du Botswana: Apport d'un modele pedagogique base sur une recherche-action participative

    NASA Astrophysics Data System (ADS)

    Gauthier, Benoit

    2000-10-01

    Cette etude s'interesse au developpement de competences de resolution de problemes environnementaux dans un contexte culturel africain. Pour y parvenir, elle elabore un modele pedagogique pouvant se situer dans le cadre theorique de la vision reflexive emergeant presentement en education relative a l'environnement (ERE). Provenant du champ d'etude de la systemique, la methodologie des systemes souples (MSS) s'avere compatible avec le cadre de la reflexivite qui est emergent. Un modele pedagogique preliminaire fut ainsi etabli en transposant et en adaptant plusieurs des principes et des constituantes de la MSS au domaine de l'ERE. Ce modele, s'appuyant sur une strategie de recherche-action, a ete ensuite mis a l'essai aupres d'enseignants du secondaire en formation au Botswana, dans le cadre de leurs activites parascolaires. Cette recherche-developpement de type participatif s'appuie sur une analyse qualitative. Durant sa mise a l'essai, le modele preliminaire a subi plusieurs modifications generees entre autres par les interactions entre les participants et le facilitateur; ces modifications suggerent fortement une prise en charge par les participants de la demarche d'investigation, condition essentielle pour le developpement de competences de resolution de problemes environnementaux. Durant la demarche de resolution du probleme, des competences relatives a l'acquisition de connaissances sur la situation investiguee et a l'action environnementale ont ete sollicitees de maniere repetee. Ceci ne semble pas avoir ete le cas pour les competences associees a la reflexion par les participants sur leurs propres perceptions (metacognition), sur celles des autres ou encore sur la nature de la connaissance (cognition epistemique). En ce qui a trait a la conception de chaque apprenant concernant le probleme environnemental etudie, les observations recueillies tout au long de la demarche suggerent, pour certains des participants, une complexification. Le modele resultant de l

  8. Zur Bahndynamik niedrigfliegender Satelliten.

    NASA Astrophysics Data System (ADS)

    Scheinert, M.

    The satellite mission ARISTOTELES and STEP give the chance to determine the gravitational field of the Earth with high accuracy and up to the short-wave domain. This is due to the expected highly sensitive observations of gravitational gradients and tracking information obtained by GPS. The goal of the dissertation is to investigate especially the potentiality of the GPS tracking data to solve the coefficients of the long-wave domain in particular. The theory of Hill's equations forms an excellent tool to analyse the orbit perturbations of the satellites moving in nearly polar, nearly circular orbits of very low altitude. The derivation of the linear perturbation theory is dealt with in detail. On the basis of the linear theory numerical simulations were carried out which proofed the impossibility to solve the long-wave domain completely from tracking data of only one of the discussed satellites. But the orbit analysis allows to set up a so-called Tailored Model in each case which may support and complete the processing of the gradiometry data.

  9. Zur Entstehung des Schallstrahlungsdruckes

    NASA Astrophysics Data System (ADS)

    Richter, G.

    Der Schallstrahlungsdruck in Flüssigkeiten und Gasen wird unter Benutzung der Bernoullischen Gleichung der Schallbewegung in der Näherung kleiner Amplituden erneut diskutiert, wobei einige Ableitungen vereinfacht und verkürzt wurden. Insbesondere wird der von G. Hertz und H. Mende erstmals beobachtete negative Schallstrahlungsdruck näher betrachtet.Translated AbstractOn the Origin of the Radiation Pressure of Sound WavesThe radiation pressure of sound waves is discussed once more using Bernoullis equation for vibrating fluids and gases. In approximations for small amplitudes some derivations could be simplified and shortened. Especially the negative radiation pressure first observed by G. Hertz und H. Mende is concidered in more details.

  10. Zur Geschichte der Geophysik

    NASA Astrophysics Data System (ADS)

    Strobach, Klaus

    1980-07-01

    Alfred Wegener's most important work, the theory of continental drift, has a key position in the history of geophysics and has crucially advanced the discussion of this central problem of geodynamics amongst supporters and adversaries. The aim of this paper is to paint a portrait of Wegener's personality, of his stations of life, and of his interests and research work. The conceptions of the origin of continents and oceans prior to Wegener, and the further development of his ideas after his death on the ice cup of Greenland 50 years ago are discussed.

  11. Psychiatric and substance use disorders in HIV/hepatitis C virus (HCV)-coinfected patients: does HCV clearance matter? [Agence Nationale de Recherche sur le SIDA et les Hépatites Virales (ANRS) HEPAVIH CO13 cohort].

    PubMed

    Michel, L; Lions, C; Winnock, M; Lang, J-P; Loko, M-A; Rosenthal, E; Marchou, B; Valantin, M-A; Morlat, P; Roux, P; Sogni, P; Spire, B; Poizot-Martin, I; Lacombe, K; Lascoux-Combe, C; Duvivier, C; Neau, D; Dabis, F; Salmon-Ceron, D; Carrieri, M P

    2016-11-01

    The objective of this nested study was to assess the prevalence of psychiatric disorders in a sample of HIV/hepatitis C virus (HCV)-coinfected patients according to their HCV status. The nested cross-sectional study, untitled HEPAVIH-Psy survey, was performed in a subset of HIV/HCV-coinfected patients enrolled in the French Agence Nationale de Recherche sur le SIDA et les Hépatites Virales (ANRS) CO13 HEPAVIH cohort. Psychiatric disorders were screened for using the Mini International Neuropsychiatric Interview (MINI 5.0.0). Among the 286 patients enrolled in the study, 68 (24%) had never received HCV treatment, 87 (30%) were treatment nonresponders, 44 (15%) were currently being treated and 87 (30%) had a sustained virological response (SVR). Of the 286 patients enrolled, 121 patients (42%) screened positive for a psychiatric disorder other than suicidality and alcohol/drug abuse/dependence, 40 (14%) screened positive for alcohol abuse/dependence, 50 (18%) screened positive for drug abuse/dependence, 50 (17.5%) were receiving an antidepressant treatment and 69 (24%) were receiving an anxiolytic. Patients with an SVR did not significantly differ from the other groups in terms of psychiatric disorders. Patients receiving HCV treatment screened positive less often for an anxiety disorder. The highest rate of drug dependence/abuse was among HCV treatment-naïve patients. Psychiatric disorders were frequent in HIV/HCV-coinfected patients and their rates were comparable between groups, even for patients achieving an SVR. Our results emphasize the need for continuous assessment and care of coinfected patients, even after HCV clearance. Drug addiction remains an obstacle to access to HCV treatment. Despite the recent advent and continued development of directly acting antiviral agents (DAAs), it is still crucial to offer screening and comprehensive care for psychiatric and addictive disorders. © 2016 British HIV Association.

  12. Inter-rater reliability of the `Merkmalprofile zur Eingliederung Leistungsgewandelter und Behinderter in Arbeit' (MELBA) in young disabled adults with psychosocial limitations.

    PubMed

    Achterberg, Thea; Wind, Haije; Prinzie, Peter; Frings-Dresen, Monique

    2013-01-01

    To evaluate the inter-rater reliability of the Merkmalprofile zur Eingliederung Leistungsgewandelter und Behinderter in Arbeit (MELBA). Twenty-five young adults with psychosocial limitations. The MELBA measures work ability in five themes: cognitive, social, work performance, psychomotor characteristics and cultural/technical communication, divided into 29 work-related items, which are assessed by work-related tasks and by observations during work performance. Two raters independently evaluated one participant during the same time/test and independently assigned scores on 19~items out of 29. For this observational study the inter-rater reliability, expressed as the Intraclass Correlation Coefficient (ICC), was calculated for every item. An ICC of at least 0.75 was considered as showing good reliability, below 0.75 was considered poor to moderate reliability. The ICC for six items was good: comprehension (0.81), attentiveness (0.84), problem solving (0.79), imagination (0.88), independence (0.79) and speed of reaction (1.0) showed good reliability. Especially the items of cognitive characteristics of the MELBA showed a good inter-rater reliability and can be used to measure work ability in people with psychosocial limitations.

  13. Proceedings from the DRG Seminar on Robotics in the Battlefield (31st) Held on 6-8 March 1991 in Paris, France. Volume A (Actes du 31ieme Seminaire sur la Robotique du Champ de Bataille, Groupe sur la Recherche pour la Defense).

    DTIC Science & Technology

    1992-06-01

    3 1ime Seminaire sur la robotique du champ de Bataille Groupe sur la Recherche pour la Defense S92-25111 92 9 14 00O ;-" SANS CLASSIFICATION...Avanc~es (ENSTA), du 6 au 8 Mars 1991, sur le theme de la Robotique du Champ de Bataille . En juillet 1985, s𔄀tait tenu, dans les mimes lietix, tin...s dens le domaine de la Robotique dui Champ de Bataille et de mesurer les progr~s accomplis pendant cette p~riode. Le S~minaire a regroup6 prds de 230

  14. Seminar on the Structure of Aeronautical R&D Held in Lisbon, Portugal on 31 May-1 Jun 1990, Patras, Greece on 4-5 June 1990 and Ankara, Turkey on 7-8 June 1990 (La Structure de la Recherche et Developpement en Aeronautique)

    DTIC Science & Technology

    1990-05-01

    long terme, h lPdchelon national d’une planification de la Recherche et Ddveloppement (R&D) a6ronautique fondde sur les objectifs nationaux h court...d’encourager dans leur tfiche difficile, ceux qui sont responsables de la planification de la R&D a6ronautique dats chacun des pays visit~s. List of...consisting of high level year. The PPRE for the fiscal year representatives of the General Staffs and (beginninq oA 1 January in France) is only the DGA

  15. Impact of HIV-1 genetic diversity on plasma HIV-1 RNA Quantification: usefulness of the Agence Nationale de Recherches sur le SIDA second-generation long terminal repeat-based real-time reverse transcriptase polymerase chain reaction test.

    PubMed

    Rouet, François; Chaix, Marie-Laure; Nerrienet, Eric; Ngo-Giang-Huong, Nicole; Plantier, Jean-Christophe; Burgard, Marianne; Peeters, Martine; Damond, Florence; Ekouevi, Didier Koumavi; Msellati, Philippe; Ferradini, Laurent; Rukobo, Sandra; Maréchal, Valérie; Schvachsa, Nilda; Wakrim, Lahcen; Rafalimanana, Christian; Rakotoambinina, Benjamin; Viard, Jean-Paul; Seigneurin, Jean-Marie; Rouzioux, Christine

    2007-08-01

    The high genetic diversity of HIV-1 has a major impact on the quantification of plasma HIV-1 RNA, representing an increasingly difficult challenge. A total of 898 plasma specimens positive for HIV-1 RNA by commercial assays (Amplicor v1.5; Roche Diagnostic Systems, Alameda, CA or Versant v3.0; Bayer Diagnostics, Emeryville, CA) were tested using the Agence Nationale de Recherches sur le SIDA second-generation (G2) real-time reverse transcriptase polymerase chain reaction (RT-PCR) test: 518 samples containing HIV-1 of known subtype, including 88 from 2 subtype panels and 430 harboring B (n = 266) and non-B (n = 164) group M HIV-1 subtypes from patients followed up in 2002 through 2005 at Necker Hospital (Paris, France), and 380 samples from 10 different countries (Argentina, Cambodia, Cameroon, Central African Republic, France, Ivory Coast, Madagascar, Morocco, Thailand, and Zimbabwe). HIV-1 RNA values obtained by G2 real-time PCR were highly correlated with those obtained by the Amplicor v1.5 for B and non-B subtypes (R = 0.892 and 0.892, respectively) and for samples from diverse countries (R = 0.867 and 0.893 for real-time PCR vs. Amplicor v1.5 and real-time PCR vs. Versant v3.0, respectively). Approximately 30% of specimens harboring non-B subtypes were underquantified by at least -0.51 log10 in Amplicor v1.5 versus 5% underquantified in G2 real-time PCR. Discrepant results were also obtained with subtype B samples (14% underquantified by Amplicor v1.5 vs. 7% by G2 real-time PCR). Similar percentages were observed when comparing results obtained with the G2 real-time PCR assay with those obtained using the Versant assay. Addressing HIV-1 diversity, continual monitoring of HIV-1 RNA assays, together with molecular epidemiology studies, is required to improve the accuracy of all HIV RNA assays.

  16. Role of uncontrolled HIV RNA level and immunodeficiency in the occurrence of malignancy in HIV-infected patients during the combination antiretroviral therapy era: Agence Nationale de Recherche sur le Sida (ANRS) CO3 Aquitaine Cohort.

    PubMed

    Bruyand, Mathias; Thiébaut, Rodolphe; Lawson-Ayayi, Sylvie; Joly, Pierre; Sasco, Annie Jeanne; Mercié, Patrick; Pellegrin, Jean Luc; Neau, Didier; Dabis, François; Morlat, Philippe; Chêne, Geneviève; Bonnet, Fabrice

    2009-10-01

    Human immunodeficiency virus (HIV)-infected patients are at higher risk of malignancies. In addition to traditional determinants, a specific deleterious effect of HIV and immunodeficiency is speculated. We aimed at studying the association between immunological and virological characteristics of HIV-infected patients in care and the risk of acquired immunodeficiency syndrome (AIDS)-defining and non-AIDS-defining malignancies. Patients consecutively enrolled in the hospital-based Agence Nationale de Recherche sur le Sida (ANRS) CO3 Aquitaine Cohort were included if the duration of follow-up was >3 months during the period 1998-2006. Multivariate modeling used an extended Cox proportional hazards model for time-dependent covariates and delayed entry. The 4194 patients included in the study developed 251 first malignancies during 22,389 person-years. A higher incidence of AIDS-defining malignancies (107 cases) was independently associated with (1) both longer and current exposures to a plasma HIV RNA level >500 copies/mL (hazard ratio [HR], 1.27 per year [P<.001] and 3.30 [P<.001], respectively) and (2) both longer and current exposure to a CD4(+) cell count <200 cells/mm(3) (HR, 1.36 per year [P<.001] and 6.33 [P<.001], respectively). A higher incidence of non-AIDS-defining malignancies (144 cases) was independently associated with longer and current exposure to a CD4(+) cell count <500 cells/mm(3) (HR, 1.13 per year [P=.01] and 2.07 [P<.001], respectively) and male sex (HR, 1.69; P=.02) but not with plasma HIV RNA level (P=.49 and P=.10 for cumulative and current exposures, respectively). Uncontrolled plasma HIV RNA level was independently associated with a higher likelihood of developing AIDS-defining malignancies, whereas immunosuppression was associated with a higher risk of developing any type of malignancies. Antiretroviral treatment should aim at reaching and maintaining a CD4(+) count >500 cells/mm(3) to prevent the occurrence of malignancy, this should be

  17. "A La Recherche Du" Quality of Life

    ERIC Educational Resources Information Center

    Jordan, Thomas E.

    2011-01-01

    This essay examines the stages of inquiry when we seek to formulate quality of life in an era before our own. There arises the question of the extent to which today's formulation of quality of life can be applied to an era far removed from our own. Implicitly, there is the nature of the time interval, T[subscript 1]...T[subscript n], and the…

  18. "A La Recherche Du" Quality of Life

    ERIC Educational Resources Information Center

    Jordan, Thomas E.

    2011-01-01

    This essay examines the stages of inquiry when we seek to formulate quality of life in an era before our own. There arises the question of the extent to which today's formulation of quality of life can be applied to an era far removed from our own. Implicitly, there is the nature of the time interval, T[subscript 1]...T[subscript n], and the…

  19. Evaluation d'impact sur la santé et évaluation d'impact sur l'équité en santé : éventail de pratiques et questions de recherche.

    PubMed

    Villeval, Mélanie; Bidault, Elsa; Lang, Thierry

    2016-09-01

    L'Evaluation d'Impact sur la Santé (EIS) se développe au niveau international et est encore au stade émergent en France. Elle vise à évaluer les effets positifs et négatifs potentiels d'un projet, d'un programme ou d'une politique sur la santé. L'objectif est de produire des recommandations en direction des décideurs, afin d'en maximiser les effets positifs et d'en diminuer les effets négatifs. L'EIS est un moyen particulièrement intéressant d'action sur les déterminants de la santé au-delà des comportements individuels et du système de santé. Les politiques de logement, de transport, de solidarité, économiques, etc. ont, en effet, des impacts souvent non prévus sur la santé. Au-delà des effets sur la santé, l'EIS doit aussi permettre d'apprécier la distribution de ces effets dans la population.Si la préoccupation pour l'équité en santé est centrale dans l'EIS, elle reste cependant difficilement traduite en pratique. Face à cette difficulté, des démarches d'évaluation d'impact ont été développées pour renforcer la prise en compte de l'équité à chaque étape de l'EIS ou « Equity Focused Health Impact Assessment », ou prendre en compte les impacts sur les inégalités de santé de façon spécifique. Ainsi, l'Evaluation de l'Impact sur l'Equité en Santé (EIES) semble, par exemple, particulièrement intéressante pour évaluer l'impact sur les inégalités de projets dans le champ sanitaire.L'EIS et l'EIES posent de nombreuses questions de recherche, notamment autour de la réunion, dans une même démarche, du politique, du citoyen et de l'expert. La participation des populations vulnérables potentiellement affectées par la politique évaluée est une valeur centrale de l'EIS, mais pose des questions d'acceptabilité sociale. La collaboration avec les décideurs politiques est également un enjeu majeur. Les difficultés méthodologiques, notamment de quantification des impacts, peuvent constituer des freins à la promotion

  20. Evaluation of an intervention program to prevent hospital-acquired catheter-associated urinary tract infections in an ICU in a rural Egypt hospital.

    PubMed

    Amine, Amira Ezzat Khamis; Helal, Mohamed Omar Mohamed; Bakr, Wafaa Mohamed Kamel

    2014-01-01

    Zielsetzung: Katheter-assoziierte Harnweginfektionen (CAUTI) sind die häufigste nosokomiale Infektion auf der ITS. Ziel der Studie war die Ermittlung der Effektivität eines Interventionsprogramms mit Implementierung eines Bundles zur Prävention von CAUTI auf einer ITS. Methode: Die Interventionsstudie wurde über einen Zeitraum von 6 Monaten durchgeführt. Während der Präinterventionsperiode wurde die Baseline für die Inzidenz von CAUTI ermittelt und mit der Inzidenz während der Postinterventionsperiode verglichen. Außerdem wurde die Compliance des Personals zur Einhaltung des Bundles ermittelt. Das CAUTI Bundle enthielt die Elemente Händehygiene, Tragen persönlicher Schutzausrüstung, Benutzung von Einmalhandschuhen, Reinigung des Meatus urethrae vor der Katheterinsertion mit steriler Kochsalzlösung, Beurteilung der Notwendigkeit des Harnwegkatheters, aseptische Harnableitung und korrekte Position des Auffangbeutels.Ergebnisse: Im Verlauf der Studie wurde bei 55 von 77 Patienten eine CAUTI diagnostiziert. Die mittlere Inzidenz betrug in der Präinterventionsperiode 90,12 CAUTI/1.000 Kathetertage und in der Postinterventionsperiode 65,69 CAUTI/1.000 Kathetertage. Die CAUTI-Rate verhielt sich indirekt proportional zur Einführung der Bundleelemente und zur Compliance der Einhaltung des Bundles. Dieser Zusammenhang war nur für die Einhaltung der Bundleelemente statistisch sicherbar (p=0,042) (rs=–0,828). Die Compliance der Pflegekräfte zur Einhaltung des Bundles wurde während der letzten 2 Monate der Postinterventionsperiode auf 100% erhöht. Schlussfolgerung: Durch verbesserte Compliance für die empfohlenen Maßnahmen zur Prävention von CAUTI konnte die Inzidenz von CAUTI auf einer ITS reduziert werden. Die Einführung eines CAUTI-Präventionsbundles ist einfach und effektiv und wird daher als Bestandteil zur Gewährleistung der Patientensicherheit empfohlen.

  1. Planeten beobachten. Praktische Anleitung für Amateurbeobachter und solche, die es werden wollen.

    NASA Astrophysics Data System (ADS)

    Roth, G. D.

    Contents: 1. Amateurastronomie und Planetenbeobachtung (H.-J. Mettig, G. D. Roth). 2. Die visuelle Beobachtung (G. D. Roth). 3. Mond- und Planetenphotographie (B. Koch). 4. Die CCD-Bildbearbeitung (R. A. Hillebrecht). 5. Tabellen zur Ermittlung der Belichtungszeiten für Mond- und Planetenaufnahmen (W. Gruschel). 6. Die lichtelektrische Beobachtung (G. D. Roth). 7. Die Objekte in Einzeldarstellungen: Merkur (D. Niechoy); Venus (D. Niechoy); Erdmond (G. D. Roth); Mars (C. M. Schambeck); Kleine Planeten (M. Hoffmann, G. D. Roth, J. Meeus); Jupiter (H.-J. Mettig, R. C. Stoyan, A. Nikolai, C. Kowalec, G. Hahn); Saturn (R. C. Stoyan, G. Hahn, H.-J. Mettig); Uranus (R. C. Stoyan); Neptun (R. C. Stoyan); Pluto (R. C. Stoyan). 8. Adressen, Literaturhinweise, Register.

  2. [The Italian version of "OREGE" (Outil de Repérage et d'Evaluation des Gestes) of the INRS (Institut national de recherche et de sécurité) for the assessment of musculoskeletal disorders of the upper limb].

    PubMed

    Apostoli, P; Bazzini, G; Sala, E; Imbriani, M

    2002-01-01

    The upper extremity work-related musculoskeletal disorders (UEWMSDs) are a heterogeneous group of disorders not yet standardised mainly epidemiological criteria for case definition. They are multifactorial, often they are work related even if sometimes they show an individual origin. In recent years they show a rapid increase but it's worth noting that this trend is also affected by a more widespread and easy recognition as work related diseases. There are many ergonomic analysis tools, currently available, that claim to accurately measure variables associated with UEWMSDs. They are essentially based on biomechanical, epidemiological and physiological approaches and identify work activities at risk of developing: OSHA's checklist, Strain Index, OCRA Index, ACGIH (Hand Activity Level). A method for the study of musculoskeletal disorders of the upper limb has been proposed by French INRS (National de Recherche et de Sécurité). It is defined as a project based on ergonomics applied to occupational medicine and it includes: (1) OSHA's checklist as a screening tool; (2) MSDs questionnaire for standardised record of symptoms and of worker's opinions (3) OREGE, (Outil de Repérage et d'Evaluation des Gestes) a exhaustive evaluation tool to be used by ergonomics-trained personnel, aimed to identify risk factors to be considered for preventive and corrective actions. OREGE includes: force evaluation through Latko's scale (which take into account: weight of objects and tools, kind of hold, pressure, vibration, temperature, use of gloves), articular position analysis, repetition analysis, synthesis of the different biomechanical risk factors, calculation of an index of risk. The authors have considered of interest to provide occupational physicians and ergonomic professionals with an Italian version of OREGE. The expected results are: a critical review of the method, a comparison with the other most known evaluation methods and the selection of the best method for specific

  3. Deep soil compaction as a method of ground improvement and to stabilization of wastes and slopes with danger of liquefaction, determining the modulus of deformation and shear strength parameters of loose rock.

    PubMed

    Lersow, M

    2001-01-01

    For the stabilization of dumps with the construction of hidden dams and for building ground improvement, for instance for traffic lines over dumps, nearly all applied compaction methods have the aim to reduce the pore volume in the loose rock. With these methods, a homogenization of the compacted loose rock will be obtained too. The compaction methods of weight compaction by falling weight, compaction by vibration and compaction by blasting have been introduced, and their applications and efficiencies have been shown. For the estimation of the effective depth of the compaction and for a safe planning of the bearing layer, respectively, the necessary material parameters have to be determined for each deep compaction method. Proposals for the determination of these parameters have been made within this paper. In connection with the stabilization of flow-slide-prone dump slopes, as well as for the improvement of dump areas for the use as building ground, it is necessary to assess the deformation behavior and the bearing capacity. To assess the resulting building ground improvement, deformation indexes (assessment of the flow-prone layer) and strength indexes (assessment of the bearing capacity) have to be determined with soil mechanical tests. Förster and Lersow, [Patentschrift DE 197 17 988. Verfahren, auf der Grundlage last- und/oder weggesteuerter Plattendruckversuche auf der Bohrlochsohle, zur Ermittlung des Spannungs-Verformungs-Verhaltens und/oder von Deformationsmoduln und/oder von Festigkeitseigenschaften in verschiedenen Tiefen insbesondere von Lockergesteinen und von Deponiekörpern in situ; Förster W, Lersow M. Plattendruckversuch auf der Bohrlochsohle, Ermittlung des Spannungs-Verformungs-Verhaltens von Lockergestein und Deponiematerial Braunkohle--Surface Mining, 1998;50(4): 369-77; Lersow M. Verfahren zur Ermittlung von Scherfestigkeitsparametern von Lockergestein und Deponiematerial aus Plattendruckversuchen auf der Bohrlochsohle. Braunkohle

  4. Agrobacterium tumefaciens Zur Regulates the High-Affinity Zinc Uptake System TroCBA and the Putative Metal Chaperone YciC, along with ZinT and ZnuABC, for Survival under Zinc-Limiting Conditions

    PubMed Central

    Chaoprasid, Paweena; Dokpikul, Thanittra; Johnrod, Jaruwan; Sirirakphaisarn, Sirin; Nookabkaew, Sumontha; Mongkolsuk, Skorn

    2016-01-01

    ABSTRACT Agrobacterium tumefaciens has a cluster of genes (Atu3178, Atu3179, and Atu3180) encoding an ABC-type transporter, here named troA, troB, and troC, respectively, which is shown here to be a zinc-specific uptake system. Reverse transcription (RT)-PCR analysis confirmed that troA, troB, and troC are cotranscribed, with troC as the first gene of the operon. The yciC (Atu3181) gene is transcribed in the opposite orientation to that of the troCBA operon and belongs to a metal-binding GTPase family. Expression of troCBA and yciC was inducible under zinc-limiting conditions and was controlled by the zinc uptake regulator, Zur. Compared to the wild type, the mutant strain lacking troC was hypersensitive to a metal chelator, EDTA, and the phenotype could be rescued by the addition of zinc, while the strain with a single yciC mutation showed no phenotype. However, yciC was important for survival under zinc limitation when either troC or zinT was inactivated. The periplasmic zinc-binding protein, ZinT, could not function when TroC was inactivated, suggesting that ZinT may interact with TroCBA in zinc uptake. Unlike many other bacteria, the ABC-type transporter ZnuABC was not the major zinc uptake system in A. tumefaciens. However, the important role of A. tumefaciens ZnuABC was revealed when TroCBA was impaired. The strain containing double mutations in the znuA and troC genes exhibited a growth defect in minimal medium. A. tumefaciens requires cooperation of zinc uptake systems and zinc chaperones, including TroCBA, ZnuABC, ZinT, and YciC, for survival under a wide range of zinc-limiting conditions. IMPORTANCE Both host and pathogen battle over access to essential metals, including zinc. In low-zinc environments, physiological responses that make it possible to acquire enough zinc are important for bacterial survival and could determine the outcome of host-pathogen interactions. A. tumefaciens was found to operate a novel pathway for zinc uptake in which Zin

  5. Recherches sur l'histoire de l'astronomie ancienne

    NASA Astrophysics Data System (ADS)

    Tannery, Paul

    2015-04-01

    Préface; 1. Ce que les Hellènes ont appelé astronomie; 2. Ce que les Hellènes ont appelé astrologie (cont.); 3. Les mathématiciens alexandrins; 4. Les postulats de l'astronomie d'après Ptlolémée et les auteurs élémentaires; 5. La sphéricité de la terre et la mesure de sa circonférence; 6. Le mouvement général des planètes; 7. Les cercles de la sphère; 8. La longueur de l'année solaire; 9. Les tables du soleil; 10. Les périodes d'Hipparque pour les mouvements lunaires; 11. Les tables de la lune; 12. Les parallaxes du soleil et de la lune; 13. Les prédictions d'éclipses; 14. La théorie des planètes; 15. Le catalogue des fixes; Appendice; Errata.

  6. Jean Piaget et sa Recherche: Search and Research.

    ERIC Educational Resources Information Center

    Gray, Elspeth M.

    1981-01-01

    The early influences on and development of Jean Piaget's thinking from which crystallized the ideas forming the foundation of his subsequent work are discussed. The influences noted are personal, intellectual, and professional. (MSE)

  7. Jean Piaget et sa Recherche: Search and Research.

    ERIC Educational Resources Information Center

    Gray, Elspeth M.

    1981-01-01

    The early influences on and development of Jean Piaget's thinking from which crystallized the ideas forming the foundation of his subsequent work are discussed. The influences noted are personal, intellectual, and professional. (MSE)

  8. Meteorites : a la recherche de leurs corps parents

    NASA Astrophysics Data System (ADS)

    Jaquet, Emmanuel

    2017-07-01

    Meteorites arrive on Earth with no indication of their cosmic provenance, yet they are essentially our only tangible witnesses of the extra-atmospheric universe. We sketch the two-century history of the search for meteorite parent bodies and present the current status of meteorites-asteroids and meteorites-planetary bodies links.

  9. Zur Biologie des marinen Heterotardigraden Tetrakentron synaptae

    NASA Astrophysics Data System (ADS)

    Kristensen, R. M.

    1980-06-01

    The life cycle of Tetrakentron synaptae Cuénot, 1892, a tardigrade closely associated with the sea cucumber Leptosynapta galliennei Herapath, was investigated in the littoral zone at Roscoff (France). Eggs and juveniles were found only in June and July, adults only from May to October. There are vagile males and stationary dwarf males. The dorsoventrally flattened body, an enlarged slimy epicuticle in females and dwarf males, the full set of claws also in juveniles, and the anus, which is in a dorsocaudal position, are indicative for an epizoic, sessile life. There is strong evidence that T. synaptae punctures the cells of L. galliennei and sucks out their content, which is indicative of parasitism.

  10. Initiativen zur marinen Naturstoffforschung in Deutschland

    NASA Astrophysics Data System (ADS)

    Zeeck, A.; Bach, G.

    1999-12-01

    Marine organisms have been found to provide new materials and bioactive agents. In Germany, two research programmes-the Forschungsschwerpunkt Meeresbiotechnologie [Research Center for Marine Biotechnology] in Lower Saxony and the national programme Marine Naturstofforschung [Research on Marine Natural Products], founded by the Bundesministerium für Bildung, Wissenschaft, Forschung und Technologie (BMBF) [Ministry of Education, Science, research, and Technology]-were specifically established to search for new drugs, enzymes, or cosmetics from marine sources. Accompanying research on marine communities and the function of the natural products they contain is expected to support these studies. In order to preserve natural resources, additional efforts are made to cultivate marine organisms in the laboratory.

  11. Zur Entwicklung der medizinischen Wissenschaften in China

    NASA Astrophysics Data System (ADS)

    Müller, Hans Kurt

    1980-02-01

    Three periods or stages can be recognized in the development of medicine in China. The first one, being the indigenous medical practice, has its own philosophical approach and can therefore not simply be combined with Western medicine. The second period, in which medical missionaries introduced modern medicine was still a time of laissez-faire and pestilence. The third stage was ushered in by the liberation in 1949 and is characterized by the fact that the government no longer regards health as the private affair of the individual but as a task for the whole community. A number of endemic and epidemic diseases were conquered mainly through close cooperation between the population and medical workers. Success must be regarded as in an important part due to land reform and the eradication of famine. Further improvement in health care will depend to a great deal on improvement in living standards and a lessening of population pressure. As family planning meets resistance for economic and other reasons, only specific measures by the state can bring about a change in attitude. The progress in preventive measures is matched by advances in the technical aspects of medicine and especially too in medical education.

  12. Zur Biosynthese von Phenylalanin und Tyrosin

    NASA Astrophysics Data System (ADS)

    Lingens, F.; Keller, E.

    1983-03-01

    With the discovery of arogenic acid two new pathways for the biosynthesis of phenylalanine and tyrosine have been revealed. The occurrence of two, three, or four pathways for the biosynthesis of phenylalanine and tyrosine in microorganisms and plants may be a useful tool for taxonomic classifications. Investigations on enterobacteriaceae, pseudomonads, flavobacteria, streptomycetes, archaebacteria, and on Sphaerotilus, Trichococcus and Leptothrix species from bulking sludge are described. The possible role of arogenate in the evolution of the pathways for tyrosine and phenylalanine biosynthesis is discussed.

  13. Zur Vorgeschichte der Padagogischen Konzepte Pestalozzis.

    ERIC Educational Resources Information Center

    Osterwalder, Fritz

    1990-01-01

    Discusses the major concepts of Johann Heinrich Pestalozzi's work, emphasizing the ways that other contemporary theorists influenced his work. Examines the application of his comprehensive philosophical systems to questions of pedagogy. (RW)

  14. Zur Biologie von Paramphiascella fulvofasciata (Copepoda, Harpacticoida)

    NASA Astrophysics Data System (ADS)

    Dahms, Hans-Uwe

    1986-09-01

    The benthic harpacticoid copepod Paramphiascella fulvofasciata Rosenfield & Coull was collected from holdfasts of Laminaria hyperborea from a subtidal area of Helgoland (North Sea). All developmental stages of P. fulvofasciata are raptorial feeders. The feeding of the nauplii is advanced by a marginal setule-crest of the labrum which prevents food-particles from being swept away. The oral appendages of the copepodites circumscribe a frustal space ventral to the mouth which facilitates uptake of food-particles. The nauplii are not able to swim and perform stalking movements with their antennal endopodites. Good swimming ability as well as digging-in-behaviour and negative phototaxis of the copepodites indicate epi- as well as inbenthic mode of life. Several life-cycle characters are described. Precopula lasts ca. one day. The mean egg-number is 27, and mean egg-diameter is 87 × 75 µm. The number of nauplii per egg (double)-sac amounts to 25 30. Developmental time at 19°C is 6 9 days (nauplii) and 20 24 days (copepodites). The whole developmental period lasts 28 days. The maximal lifespan in the laboratory is 193 days. Sex-ratio is almost balanced. Females produce egg-sacs more than 3.5 times during their life period. Seasonal effects on reproductive activity have not been detected in laboratory cultures.

  15. Zur chemie der marsoberfläche

    USGS Publications Warehouse

    Keil, Klaus; Clark, Benton C.; Baird, A.K.; Toulmin, Priestley; Rose, Harry J.

    1978-01-01

    Analyses of 13 samples of Martian surface materials with the Viking X-ray fluorescence spectrometers show SiO2 similar to that of terrestrial mafic rocks, whereas Fe2O3, Cl, and S are higher and Al2O3, K2O, Rb, Sr, Y, and Zr are lower. Low totals suggest presence of CO2, H2O, and Na2O. Duricrust fragments are higher in S than fines, but samples from both landing sites are surprisingly similar. We suggest that Martian surface materials are aeolian deposits of complex mixtures of weathering products of maficultramafic rocks, possibly consisting of iron-rich clays, sulfates, iron oxides, carbonates, and chlorides.

  16. Zur Ätiologie des Mongolismus

    NASA Astrophysics Data System (ADS)

    Wagenbichler, P.

    1981-02-01

    Beside the rare cases of translocation mongolism, Down syndrom is caused by meiotic malsegregation of chromosomes No. 21. The meiotic error can take place in both sexes and was found twice as frequently in the female as in the male. The same 2∶1 ratio was found concerning nondisjunction in the first and in the second meiotic division. The rate of meiotic errors, which occur at random, is largely dependent on age; this tendency is more pronounced in oogenesis than in spermatogenesis. The results of prenatal chromosomal diagnosis indicate that the recurrence risk of trisomy 21 is not above the age-dependent average.

  17. Limitierungen bei der Ermittlung der Grundwasserfließrichtung in tiefen Aquiferen am Beispiel des Malms im Süddeutschen Molassebecken

    NASA Astrophysics Data System (ADS)

    Savvatis, Alexandros; Steiner, Ulrich; Huber, Bernhard; Fritzer, Thomas; Schneider, Michael

    2015-12-01

    The groundwater flow direction in deep inclined aquifers is generally determined from contour maps based on the conversion of the reservoir pressure from deep wells to standardized groundwater levels. The standardizing is done with a representative water column of constant density in which an increasing depth of the aquifer has an increasing influence on the calculated groundwater levels. However, integration of new pressure data from recently drilled geothermal wells in the Malm of the South German Molasse Basin in the greater area of Munich led to a hydrogeologically unrealistic groundwater flow direction below the Alps. The present work demonstrates the applied method for standardization, performs an error analysis, and shows the limits of the applicability of this method. An alternative approach is introduced along with a concrete example where the local flow direction is determined by neighboring wells (cluster method). A sensitivity analysis with respect to the uncertainty in temperature shows that this approach provides realistic results from realistic input scenarios. The presented cluster method is therefore able to provide pilot points for calibration/verification of a basin-scale groundwater flow model.

  18. Choosing a measure of Health Related Quality of Life.

    PubMed

    Robinson, P G

    2016-06-01

    This paper provides practical advice on the choice of health related quality of life measures. It starts by making explicit a series of underlying assumptions and then advises on selecting a measure as a trade-off between three sets of conditions: The purpose of collecting HQoL information, which considers the objectives of the study, the level of analysis, the population to be studied and the audience to whom the data will be presented. The qualities of the measure, including the need for a strong conceptual basis, pragmatic considerations, face and content validity, adequate psychometric properties and for the measure to be acceptable to the people participating in the study. The use of the measure, including the mode of administration and resource requirements. An earlier version of this paper was published as Robinson, P.G. (2016): Wahl der messinstrumente zur ermittlung der gesundheitsbezogenen lebensqualitat. In: Kovacs, L., Kipke, R., Lutz, R. (eds) Lebensqualitat in der medizin. Wiesbaden: Springer VS, pp201-222.

  19. Evidence mapping for decision making: feasibility versus accuracy - when to abandon high sensitivity in electronic searches.

    PubMed

    Buchberger, Barbara; Krabbe, Laura; Lux, Beate; Mattivi, Jessica Tajana

    2016-01-01

    Hintergrund: Evidence Mapping ist eine vergleichsweise neue methodische Herangehensweise, die für die Entwicklung von Forschungsfragen und Entscheidungen über deren Relevanz oder Priorität hilfreich sein kann. Allerdings stellt die Menge der heutzutage zur Verfügung stehenden Daten eine Herausforderung für Wissenschaftler dar, die zum Teil mit Ergebnissen von Datenbankrecherchen konfrontiert sind, die über 30.000 identifizierte Literaturstellen für ein erstes Screening umfassen.Ziele: Zur Überprüfung der Eignung des Themas „Diabetes und Fahrerlaubnis“ als Fragestellung für eine evidenzbasierte nationale klinische Leitlinie wurde ein Evidence Mapping durchgeführt. Darüber hinaus wurde eine hoch sensitive mit einer hoch spezifischen Suchstrategie verglichen.Methoden: Auf der Basis eines systematischen Reviews waren die Datenbankrecherchen auf den Zeitraum von 2002 bis heute begrenzt sowie auf deutsche und englische Publikationen.Ergebnisse: Aufgrund der stark fokussierten Fragestellung und der Begrenzungen ergab die hoch sensitive Recherche eine handhabbare Menge von Literaturstellen, die ausreichend Evidenz enthielten, um die Fragestellung nach der Eignung des Themas für eine evidenzbasierte Leitlinie positiv beantworten zu können. Unter Anwendung der hoch spezifischen Suchstrategie wurde eine Reduktion der Literaturstellen um 25% erreicht, mit der 88% der relevanten Literaturstellen identifiziert werden konnten.Schlussfolgerung: Um eine Übersicht über ein Forschungsgebiet zu erlangen, ist im Gegensatz zu systematischen Reviews, die zur Reduktion von Bias die Darstellung der vollständigen, identifizierbaren Evidenz enthalten müssen, keine Recherche von größter Genauigkeit erforderlich. Unter Berücksichtigung dieses methodischen Unterschieds kann unter Anwendung einer hoch spezifischen Recherche anstelle einer hoch sensitiven eine große Menge zu bearbeitender, aber überflüssiger Informationen vermieden werden.

  20. Integrierter Ansatz zur Beurteilung eines Aufsuchungsantrages auf Schiefergas in Hessen

    NASA Astrophysics Data System (ADS)

    Fritsche, Johann-Gerhard; Brodsky, Jan; Heggemann, Heiner; Hoffmann, Michaela; Hottenrott, Martin; Kracht, Matthias; Reischmann, Thomas; Rosenberg, Fred; Schlösser-Kluger, Inga

    2016-06-01

    In the context of an application for a shale gas exploration license including hydraulic fracturing, the Geological Survey of Hessen (HLNUG) has grouped and ranked structural geological regions in terms of their shale gas potential and the function of overlying rocks as barriers. Tectonic and structural features as well as the type of reservoir have been examined. Rock units overlying the shale gas layers have been classified as hydrogeological units and divided into aquifers and hydraulic barriers. Possible effects on drinking water abstraction facilities, mineral springs and water for industrial use have also been estimated, followed by an analysis of competing requirements for land use. A potential for shale gas can only be identified in a region north of Kassel, covering about 16 % of the claim area. Approximately 65 % of this region is overlapped by protection areas for drinking water and mineral springs, nature reserves and many other areas of public interest.

  1. Zeitspiel ist keine Alternative - Warum der Wandel zur Pflicht wird

    NASA Astrophysics Data System (ADS)

    Dieper, Stephan

    "Wege entstehen dadurch, dass man sie geht." (Franz Kafka) Die Welt der Digitalisierung ist voll von Wegen, die jemand gegangen ist, bevor dort ein Weg war. Manche dieser Wege stellten sich als Sackgasse heraus, manche als Abkürzung und aus anderen wurden ganze Wegenetze und Städte. Die Energiewelt wird durch den digitalen Wandel nicht verschont bleiben. Durch die intelligenten Messsysteme und die zugehörigen, neuen Strukturen werden energiefremden Wettbewerbern Chancen zum Markteintritt eröffnet. EVUs müssen sich darauf einstellen, dass der permanente Wandel nicht mehr enden wird. Doch auch den EVUs eröffnen sich Optionen. Um erfolgreich zu sein, müssen sie lernen loszugehen, ohne das genaue Ziel zu kennen.

  2. Definition von Datenarten zur konsistenten Kommunikation im Unternehmen

    NASA Astrophysics Data System (ADS)

    Piro, Andrea; Gebauer, Marcus

    Probleme in der Informationsqualität (IQ) treten in den unterschiedlichsten Bereichen eines Unternehmens auf und werden durch die unterschiedlichsten Bereiche verursacht. Daher ist es um so wichtiger, diese Probleme klar und eindeutig kommunizieren zu können. Insbesondere wenn Kollegen fachübergreifend IQ-Probleme beheben wollen, kann dies schwierig sein. Erst wenn klar ist, worüber geredet wird, und häufig sind dies Datenfelder und ihr Inhalt, kann das Problem eindeutig beschrieben und gelöst werden.

  3. Definition von Datenarten zur konsistenten Kommunikation im Unternehmen

    NASA Astrophysics Data System (ADS)

    Piro, Andrea; Gebauer, Marcus

    Probleme in der Informationsqualität (IQ) treten in den unterschiedlichsten Bereichen eines Unternehmens auf und werden durch die unterschiedlichsten Bereiche verursacht. Daher ist es um so wichtiger, diese Probleme klar und eindeutig kommunizieren zu können. Insbesondere wenn Kollegen fachübergreifend IQProbleme beheben wollen, kann dies schwierig sein. Erst wenn klar ist, worüber geredet wird, und häufig sind dies Datenfelder und ihr Inhalt, kann das Problem eindeutig beschrieben und gelöst werden.

  4. Eine FPAA-Architektur zur rekonfigurierbaren Instantiierung von zeitkontinuierlichen Analogfiltern

    NASA Astrophysics Data System (ADS)

    Becker, J.; Manoli, Y.

    2005-05-01

    Im Folgenden wird eine neue Methodik von FPAAs (Field Programmable Analog Arrays) gezeigt, die speziell für die Instantiierung von zeitkontinuierlichen (continuous-time, CT) Analogfiltern in Hardware entwickelt wurde. Die Chiptopologie beinhaltet 17 digital konfigurierbare analoge Blöcke (configurable analog blocks, CABs), die durch ein hexagonales Netzwerk miteinander verbunden sind. Jeder CAB ist aus einstellbaren Gm-C Integratoren aufgebaut, welche das analoge Signal sowohl formen und seinen Weg durch die Matrix festlegen, gleichzeitig aber auch die Grundbausteine für zeitkontinuierliche Hochfrequenzfilter darstellen. Intelligente Pufferspeicher für die Ein-/Ausgänge (IO-buffer) garantieren die Rekonfigurierung der Matrix mit minimaler Störung des kontinuierlichen Analogsignals. Die Architektur wird als Hardwareplattform für beliebige Schaltungen, welche aus einer gegebenen Anzahl an Gm-C-Zellen bestehen, eingeführt und verifiziert bevor eine exemplarische Instantiierung eines Butterworth Filters 4. Ordnung in Biquad Anordnung gezeigt wird.

  5. Zur Lyrik in der Schule (Lyrics in the School).

    ERIC Educational Resources Information Center

    Wyss, Emil

    1954-01-01

    Good German lyric poetry is a union in a higher reality of the inner life with the world of objects. Its use of musical effect, metaphor, and the mysterious and imponderable creates for the trained reader a sense of permanent beauty. The German-speaking, adolescent, secondary-school student is ripe for such an experience, having reached a point in…

  6. Zur Wortbildung im Russischen (10) (On Russian Word Formation [10])

    ERIC Educational Resources Information Center

    Friedrich, Wolf

    1974-01-01

    Tenth of a regular series on contemporary Russian word formation, this article gives examples of: 1) four types of standard formation, 2) rare cases where compounds are produced with no combining vowel, and 3) appositive noun compounds. (Text is in German.) (TL)

  7. Planungsmodelle und Planungsmethoden. Anhaltspunkte zur Strukturierung und Gestaltung von Planungsprozessen

    NASA Astrophysics Data System (ADS)

    Diller, Christian; Karic, Sarah; Oberding, Sarah

    2017-06-01

    The topic of this article ist the question, in which phases oft he political planning process planners apply their methodological set of tools. That for the results of a research-project are presented, which were gained by an examination of planning-cases in learned journals. Firstly it is argued, which model oft he planning-process is most suitable to reflect the regarded cases and how it is positioned to models oft he political process. Thereafter it is analyzed, which types of planning methods are applied in the several stages oft he planning process. The central findings: Although complex, many planning processes can be thouroughly pictured by a linear modell with predominantly simple feedback loops. Even in times of he communicative turn, concerning their set of tools, planners should pay attention to apply not only communicative methods but as well the classical analytical-rational methods. They are helpful especially for the understanding of the political process before and after the actual planning phase.

  8. Glossary of Educational Technology Terms = Glossar zur Bildungstechnologie.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France).

    This glossary, prepared by the International Council of Educational Media (ICEM), groups in one volume the English and German terms related to educational technology in order to facilitate understanding of these terms and to promote communication at the international level. Analysis of terms from the fields of audiovisual teaching, programmed…

  9. Ein physikalisch basiertes Modellkonzept zur Transportmodellierung in gekoppelten Hydrosystemen

    NASA Astrophysics Data System (ADS)

    Delfs, J.-O.; Park, C.-H.; Kolditz, O.; Kalbus, E.

    2009-09-01

    Hydrosystems are very complex systems with numerous processes occuring simultaneously at different spatial and temporal scales. In this paper we present the concept of a compartment approach for the analysis of coupled hydrosystems including heat and mass transport. In this concept, flow and transport processes are coupled via their compartment (or process domain) boundaries without giving up the computational necessities and optimisations for the numerical solution of each individual process. In this new approach, random walk particle tracking (RWPT) methods are integrated into the coupled hydrosystem analysis. We briefly introduce the RWPT method and the governing equations for water flow, heat, and mass transport in aquifers, soils and on surfaces. Flow processes are described by diffusion equations (Darcy equation for groundwater flow, Richards equation for flow in the unsaturated zone, and the diffusive wave approximation for overland flow) which are coupled by exchange fluxes. Transport processes are described by advection-diffusion equations and coupled with the exchange fluxes by advection. We present three application examples concerning flow, mass and heat transport in coupled hydrosystems based on Horton- and Dunne overland flow as well as on hyporheic flows.

  10. Magnetisch abgeschirmte Kabine zur Aufnahme kleinster magnetischer und elektrischer Biosignale

    NASA Astrophysics Data System (ADS)

    Mager, Albrecht

    1982-08-01

    An extraordinary magnetically shielded room was designed and constructed for the Physikalisch-Technische Bundesanstalt Institut Berlin to measure extremely weak magnetic fields of the human body with SQUID-magnetometers. The inner and the outer dimensions of the cube-shaped room are 2.25 m and about 5 m. The shield has 6 magnetic shells of a high-permeability alloy and an inner shell welded of massive copper plates. The total weight of the magnetic alloy is about 10 t and about 5 t for the inner copper shell. The required shielding factor of 1000 for the very low frequencies was greatly surpassed by the real measured value of 10000 (measured without any compensating or idealizing method). With rising frequencies the shielding factor reaches higher values, at 50 Hz more than 100000 and a million for 1000 Hz. First measurements in the shielded room with high-resolution magnetocardiograms (HR MCG) and high-resolution electrocardiograms (HR ECG) showed new methods for non-invasive electrophysiological investigations in man.

  11. Interkulturelles Lernen — Zur Grundlegung eines didaktischen Prinzips interkultureller Begegnungen

    NASA Astrophysics Data System (ADS)

    Sandhaas, Bernd

    1988-12-01

    In the Federal Republic of Germany there have in recent years been many varied encounters between Germans and representatives of other cultures, particularly those from Third World countries. These have increasingly been organized with an awareness of global interdependence and have as a result opened the door to the influence of foreign cultures and to an unmistakeable movement in the direction of a multicultural society. An intercultural pedagogical approach and didactic theory are faced with the task of resolving the consequent problems related to education and training. The author firstly attempts to systematize as a typology the practice of learning as it occurs in intercultural encounters in so far as this relates to the Federal Republic of Germany. He suggests that `intercultural learning' should be seen as the didactic principle underlying the organization of learning in such encounters. Through a detailed discussion of his central concepts of `culture' and `learning' and of the issue of `interculturalism', and by sketching a theoretical model of the stages and goals of the learning taking place, he then makes plain the necessary enlargement of the German concept of `Kultur' and the process of differentiation which the concept of learning will have to engage in if it is to be applicable to educational activity in international or intercultural contexts.

  12. Methodenvergleich zur Bestimmung der hydraulischen Durchlässigkeit

    NASA Astrophysics Data System (ADS)

    Storz, Katharina; Steger, Hagen; Wagner, Valentin; Bayer, Peter; Blum, Philipp

    2017-06-01

    Knowing the hydraulic conductivity (K) is a precondition for understanding groundwater flow processes in the subsurface. Numerous laboratory and field methods for the determination of hydraulic conductivity exist, which can lead to significantly different results. In order to quantify the variability of these various methods, the hydraulic conductivity was examined for an industrial silica sand (Dorsilit) using four different methods: (1) grain-size analysis, (2) Kozeny-Carman approach, (3) permeameter tests and (4) flow rate experiments in large-scale tank experiments. Due to the large volume of the artificially built aquifer, the tank experiment results are assumed to be the most representative. Hydraulic conductivity values derived from permeameter tests show only minor deviation, while results of the empirically evaluated grain-size analysis are about one magnitude higher and show great variances. The latter was confirmed by the analysis of several methods for the determination of K-values found in the literature, thus we generally question the suitability of grain-size analyses and strongly recommend the use of permeameter tests.

  13. Experimentelles FMCW-Radar zur hochfrequenten Charakterisierung von Windenergieanlagen

    NASA Astrophysics Data System (ADS)

    Schubert, Karsten; Werner, Jens; Schwartau, Fabian

    2017-09-01

    During the increasing dissemination of renewable energy sources the potential and actual interference effects of wind turbine plants became obvious. Turbines reflect the signals of weather radar and other radar systems. In addition to the static radar echoes, in particular the Doppler echoes are to be mentioned as an undesirable impairment Keränen (2014). As a result, building permit is refused for numerous new wind turbines, as the potential interference can not be reliably predicted. As a contribution to the improvement of this predictability, measurements are planned which aim at the high-frequency characterisation of wind energy installations. In this paper, a cost-effective FMCW radar is presented, which is operated in the same frequency band (C-band) as the weather radars of the German weather service. Here, the focus is on the description of the hardware design including the considerations used for its dimensioning.

  14. Neue Norm zur thermischen Nutzung des Grundwassers in der Schweiz

    NASA Astrophysics Data System (ADS)

    Poppei, Joachim; Altenburger, Adrian; Mettauer, Pascal; Papritz, Kaspar; Signorelli, Sarah

    2016-03-01

    The utilization of groundwater for heating and cooling is the second most common application of shallow geothermal energy. In contrast to closed-loop ground-coupled heat exchangers, changes in groundwater temperature and pumping in open-loop systems can have far-reaching impacts, often exceeding property limits. The limited resources on one hand, and the justified protection of groundwater on the other hand, result in a need for standardisation of this energy source. The Swiss Society of Engineers and Architects (SIA) released the standard 384/6 "Ground-coupled heat exchanger" in 2010, which was followed in April 2015 by standard 384/7 "Thermal utilization of groundwater". The authors—associates and head of the commission—give an overview on how to deal with the specific needs, resulting from the interdisciplinary subject area, and from differences in demands and claims of the involved parties. We show how the challenges in quality assurance, functionality and environmental aspects are being met with a consensus of planners, managers and authorities during the implementation of the new standard.

  15. Ultrastrukturelle Untersuchungen zur Morphologie und Genese der Spermien von Archaeogastropoda

    NASA Astrophysics Data System (ADS)

    Kohnert, R.; Storch, V.

    1983-03-01

    The sperm cells of Patella coerulea (Patellacea), Monodonta turbinata, and Gibbula tumida (Trochacea) were investigated by means of transmission electron microscopy. They belong to the primitive type (sensu Franzén) and have more features in common with primitive Bivalvia sperms than with Neritacea. Their head contains an apical acrosome and a roundish nucleus followed by 4 or 5 mitochondria and a centriolar apparatus which consists of two centrioles, one of which bears a flagellum. The sperm cells of Monodonta and Gibbula are very similar to each other and differ mainly in size; Patella exhibits more differences (very small acrosome, subacrosomal space, variable number of spherical mitochondria (origin of spermic dimorphism ?). The development of the sperm cells shows no peculiarities.

  16. Evolutionäres Graphmatching zur Handknochen-Identifikation

    NASA Astrophysics Data System (ADS)

    Fischer, Benedikt; Fritsche, Armin; Thies, Christian; Deserno, Thomas M.

    Im medizinischen Umfeld ist häufig eine Identifikation lokaler Bildinhalte (z.B. Organe) erforderlich. Dazu lassen sich Bildinhalte als Graphstruktur abstrahieren und mit für die jeweilige Anwendung statistisch ermittelten Strukturprototypen vergleichen. Die Identifikation unbekannter Inhalte zu den Prototypen entspricht dann einem Graphmatching. In dieser Arbeit wird dazu ein auf evolutionärer Spieletheorie basierender Ansatz verwendet. Die Praxistauglichkeit wird am Beispiel der Identifikation von 19 Handknochen in 96 Handradiographien evaluiert und mit weiteren Matchingverfahren verglichen. Bei durchschnittlich 2.300 hierarchisch segmentierten Regionen je Radiographie werden mit 34 regionalen und 12 relationalen Merkmalen Werte von bis zu 71,63%, 65,76% bzw. 64,08% für Recall, Precision bzw. F-Measure für 27 unterschiedliche Parametrierungen erzielt.

  17. Zur Arbeit mit Texten (On Working with Texts)

    ERIC Educational Resources Information Center

    Schrand, Heinrich

    1977-01-01

    Using as an example Lesson 21 of the textbook "Lebendiges Englisch" ("Living English") (Munich, Hueber 1976), some hints are given on how to work on the lesson. The suggestions for discussion bear on the treatment of dialogs and reading texts. (Text is in German.) (IFS/WGA)

  18. Amor und der Abstand zur Sonne. Geschichten aus meinem Kosmos

    NASA Astrophysics Data System (ADS)

    Kippenhahn, Rudolf

    2001-10-01

    R. Kippenhahn hat in vielen Büchern die Astronomie populär gemacht. Ihn interessieren dabei immer auch die kuriosen Aspekte seiner Wissenschaft. Von ihnen erzählt er in den kleinen Geschichten dieses Buches.

  19. Zur Biologie des Planktons des Königshafens (Nordsylter Wattenmeer)

    NASA Astrophysics Data System (ADS)

    Martens, P.

    1982-06-01

    From May 1979 on, the following parameters were measured at a station in the inlet of Königshafen near List (Island of Sylt): temperature, salinity, mesozooplankton (>76 µm), chlorophyll-a, seston dry weight, oxygen and phytoplankton-nutrients (NH4-N, NO2-N, NO3-N, PO4-P, SiO3-Si). A multiple regression analysis showed the interrelationships between the parameters measured. Tidal influences on zooplankton and seston dry weight could be observed. At low tide, the amount of zooplankton (not counting the harpacticoid copepods) declines and the number of harpacticoid copepods rises as does the seston dry weight too. The chlorophyll-a content is a function of the phytoplankton-nutrients. An increase in chlorophyll-a leads to a decrease in nitrogen and silicate concentrations. Phosphate, due possibly to a sewage inlet into the Königshafen, is not a limiting factor. The availability of nutrients is influenced by temperature, salinity and the tidal cycle. The amount of oxygen is dependent on water temperature and seston dry weight. High water temperatures and a high seston content lead to a decrease in oxygen concentrations.

  20. [Leben im Eismeer - Tauchuntersuchungen zur Biologie arktischer Meerespflanzen und Meerestiere

    PubMed

    Lippert; Karsten; Wiencke

    2000-01-01

    Die Maske wird nochmals auf Dichtigkeit überprüft, der Knoten der Sicherungsleine mit zwei halben Schlägen fixiert, dann rutscht die Taucherin von der Eiskante in das kalte Wasser. Eine halbe Stunde vergeht, bevor ihr Kopf wieder aus dem Eisloch auftaucht und sie ein großes Sammelnetz nach oben reicht, gefüllt mit verschiedenen Arten von Makroalgen. Obwohl noch große Flächen des Kongsfjordes im arktischen Spitzbergen zugefroren sind und das Festland von einer dicken Schneedecke bedeckt ist, hat unter Wasser in den Algenwäldern bereits der Sommer und damit die Saison der Meeresbiologen begonnen.

  1. Methodisches Vorgehen zur integralen Auslegung von Produkt und Montage

    NASA Astrophysics Data System (ADS)

    Meyer, André; Grauer, Matthias; Rittner, Martin; Zeltner, Stefan; März, Martin; Egelkraut, Sven; Birkner, Klaus; Braun, Steven

    Die Produktlebenszyklen werden durch den steigenden Wettbewerbsdruck stetig kürzer. Dies veranlasst Unternehmen, Produktinnovationen in immer geringeren Zeitabständen auf den Markt zu bringen und Produktentwicklungszeiten zu verkürzen. Zusätzlich wirken sich erhöhte Anforderungen bezüglich Produktzuverlässigkeit und -lebensdauer erschwerend aus. Um dieser Herausforderung zu begegnen ist eine enge Zusammenarbeit zwischen Entwicklung, Konstruktion, Fertigungsplanung und Prozessentwicklung unabdingbar, denn nur durch eine optimale Abstimmung von Konstruktion und Fertigungsprozess lassen sich die hohen Qualitätsanforderungen erfüllen.

  2. Zur Struktur der Solenocyten (Cyrtocyten) von Anaitides mucosa (Annelida, Polychaeta)

    NASA Astrophysics Data System (ADS)

    Hausmann, K.

    1981-12-01

    Based on electron microscopic observations, the structure of the solenocytes of A. mucosa is described. The tube of the solenocyte is made up of 14 15 rods. These rods, which are filled with regularly packed filaments, are interconnected by an amorphous to filamentous substance. A single flagellum, lying in the tube, is surrounded by a sheet of amorphous material. The functional organization of the solenocytes is discussed.

  3. Bewehrte Betonbauteile unter Betriebsbedingungen: Forschungsbericht

    NASA Astrophysics Data System (ADS)

    Eligehausen, Rolf; Kordina, Karl; Schießl, Peter

    2000-09-01

    Vorwort. Teil I: Rißbreiten (Gert König) 1 Ein mechanisches Modell zur Erhöhung der Vorhersagegenauigkeit über die Rißbreiten unter Betriebsbedingungen (Gert König und Michael Fischer). 1.1 Einleitung und Zielsetzung. 1.2 Versuchsprogramm. 1.3 Meßtechnik. 1.4 Belastung und Versuchsdurchführung. 1.5 Literatur. 2 Rißbreiten und Verformungszunahme vorgespannter Bauteile unter wiederholter Last - und Zwangbeanspruchung (Gert König und Michael Fischer). 2.1 Einleitung und Zielsetzung. 2.2 Versuchsprogramm. 2.3 Auswertung. 2.4 Ausblick. 2.5 Literatur. 3 Rißverhalten von Beton bei plötzlicher Abkühlung (Viktor Mechtcherine und Harald S. Müller). 3.1 Einleitung. 3.2 Experimentelle Untersuchungen. 3.3 Formulierung eines Stoffgesetzes für thermisch beanspruchten Beton. 3.4 Riß entwicklung in einer Betonplatte unter Temperaturschock. 3.5 Zusammenfassung. 3.6 Literatur. 4 Stahlfaserbeton unter Betriebsbedingungen bei Dauerbeanspruchung (Bo Soon Kang, Bernd Schnütgen und Friedhelm Stangenberg). 4.1 Einleitung. 4.2 Wirkung von Stahlfasern im Beton. 4.3 Versuchsprogramm. 4.4 Untersuchungen zum Verbundverhalten. 4.5 Untersuchungen zum Verhalten unter Biegebeanspruchung. 4.6 Theoretische Untersuchungen. 4.7 Literatur. 5 Experimentelle Untersuchungen an Stahlbeton-Zugkörpern unter wiederholter Belastung zur Ermittlung des versteifenden Einflusses der Mitwirkung des Betons zwischen den Rissen (Petra Seibel und Gerhard Mehlhorn). 5.1 Einleitung. 5.2 Ansatz zur Bestimmung der Mitwirkung des Betons zwischen den Rissen nach Eurocode 2, Model Code 90 und Günther. 5.3 Experimentelle Untersuchungen. 5.4 Ergebnisse. 5.5 Zusammenfassung. 5.6 Literatur. 6 Riß- und Verformungsverhalten von vorgefertigten Spannbetonträgern unter Betriebsbedingungen bei besonderer Berücksichtigung des Betonalters (Monika Maske, Heinz Meichsner und Lothar Schubert). 6.1 Einleitung. 6.2 Beschreibung der Fertigteilträger. 6.3 Belastungsversuche. 6.4 Ergebnisse. 6.5 Zusammenfassung. 6

  4. Le discours oral en elaboration: Directions de recherche (Oral Discourse in Process: Research in Progress).

    ERIC Educational Resources Information Center

    Carton, Francis M.

    Research is in progress on oral interactive discourse, that is, discourse produced by several participants working in collaboration. The intent of the research is to investigate how the discourse is organized at several different levels of structure (acts, sequences of acts, interactive structure, propositional content, and formal realizations).…

  5. Community Development and Research. Aboriginal Peoples Collection = Developpement Communautaire et Recherches. Collection sur les Autochtones.

    ERIC Educational Resources Information Center

    Ministry of the Solicitor General, Ottawa (Ontario).

    This report provides Canadian Aboriginal communities with information and resources for carrying out participatory action research and applying the results to community development. Presented in English and French, the report is based on a literature review and a 2-day focus group involving 14 community development experts, Aboriginal community…

  6. [Current demographic research projects at the Centre de Recherches Economiques et Demographiques].

    PubMed

    Ngwe, E

    1984-01-01

    The Center for Economic and Demographic Research (CRED), created in 1980 as 1 of 4 research centers of the Institute of Human Sciences, is currently conducting 3 research operations and other projects as well despite its still small staff of only 4 demographers. 1 of 2 research projects concerning internal migration, the survey of demographic processes and rural exodus in the north and west of Cameroon, was a 2-round survey on a sample of about 36,000 persons. Fieldwork took place in April 1982 and April 1983 and analysis of data is currently underway. The survey had several objectives: a study of the concept of population pressure; a comparison of the role of population pressure in the rural exodus in 2 zones with similar densities but different migratory behavior; a study of levels, correlates, and consequences of migration for sending areas and the links between migrants and their places of origin; improvement of data collection techniques for migration research; and provision of data to assist in design of a rural development policy that would increase retention of rural population. The 2nd internal migration study is a survey of migration among secondary school students. Results of a pilot survey among 2408 students in the west and northwest provinces interviewed in March 1984 are being analyzed. The main survey is planned for January 1985 and is intended to measure the volume and duration of migration among students, to study the characteristics of migrants, and to analyze the causes of movements. The sample size is expected to be about 40,000. A pilot study for the survey of infant mortality in rural areas was begun in March 1984 and was intended primarily to determine the feasibility of data gathering techniques for a larger study of the levels and correlates of infant mortality. The methodology calls for the sample of newborns to be visted at 1, 3, 6, 9, and 12 months. Arrondissements with high and low infant mortality are to be studied in 3 different ecological zones: sahelian, equatorial forest, and Sudanian. The hypothesis to be tested is that, if physical conditions are the same within a zone, demographic differentials must be explanied by cultural or socioeconomic factors which are amenable to modification by a suitable development policy. Samples of about 1000 newborns are to be followed in each of the 6 categories. The Department of Demographic Research has also undertaken development of a bibliographic data base for population studies in Cameroon. The data base, called POPCAM, has more than 2400 citations thus far.

  7. Neuropsychologie et Neurolinguistique. Themes de recherche commune (Neuropsychology and Neurolinguistics. Themes of Common Research)

    ERIC Educational Resources Information Center

    Weigl, Egon; Bierwisch, Manfred

    1976-01-01

    By presenting preliminary results of joint experiments conducted by speech pathologists and linguists, this article discusses the possibility of further neuropsycholinguistic research. (Text is in French.) (CLK)

  8. Towards a Canadian Educational Research Policy. (Vers une Politique Canadienne de la Recherche Pedagogique.)

    ERIC Educational Resources Information Center

    Canadian Council for Research in Education, Ottawa (Ontario).

    Based on workshop discussions, this report attempts to lay down broad guidelines for Canadian educational research and development. The guidelines postulate that a comprehensive policy should include a pattern of priorities that (1) encourage the development of high quality scholarly institutions, (2) provide for risk capital for exploratory basic…

  9. Education Relative a l'Environnement: Regards, Recherches, Reflexions. Volume 2.

    ERIC Educational Resources Information Center

    2000

    This document reports the work of inter-university research taken in Montreal in November, 2000 of research on the evaluation of education relative to the environment. Papers include: (1) "Quelle evaluation pour quelle education relative l'environnement?" (Georgia Liarakou and Eugenie Flogaitis); (2) "Quand evaluer c'est apprendre ensemble: Une…

  10. Research and the Secondary School Curriculum = La Recherche et le Programme d'Enseignement Secondaire.

    ERIC Educational Resources Information Center

    Ruddock, Jean

    This paper outlines the diversity of support for educational research and the relatively little influence that educational research has had on recent United Kingdom policy for the secondary school curriculum. The document goes on to describe the major change facing U.K. secondary schools: the introduction of the national curriculum and a related…

  11. Virtual Interfaces: Research and Application (Les Interfaces Virtuelles entre Recherche et Applications).

    DTIC Science & Technology

    1994-05-01

    donndes et de la d6tection des mouvements humains, alli6s aux mod6les informatis6s des milieux naturels et artificiels, ont conduit A la mise el pltace...d’interfaces dites virtuelles. Les interfaces virtuelles offrent plus de souplesse et de naturel et elles sont donc envisag6es pour les domaines tels...contr6leurs a6ricns. principes d𔄀tude du langage naturel . Basd sur l’utilisation concomnitante d’une interface 11 GENERALITES vocale (synth~se et

  12. Education Relative a l'Environnement: Regards, Recherches, Reflexions. Volume 4.

    ERIC Educational Resources Information Center

    2003

    This document takes a critical look at the relationship between environment, culture, and development from the perspective of education relative to the environment. Papers include: (1) "Education a l'environnement ou acculturation?" (Jean-Etienne Bidou); (2) "Environnement et developpement: La culture de la filiere ONU" (Lucie Sauve, Tom Berryman,…

  13. Recherche De Correlations Temporelles Des Muons Cosmiques Avec Macro Et Perte D'Energie Des Nuclearites

    NASA Astrophysics Data System (ADS)

    Moussa, A.

    2009-11-01

    The first parts of the thesis recalls the main features of the large MACRO experiment at the underground Gran Sasso Laboratory. It then describes the atmospheric muons measured by the experiment and the selection criteria to obtain and analyze a large sample of cosmic muons. The time series of MACRO muons was analyzed with two complementary approaches: search for the occurrence of bursts of muon events and search for periodicities in the muon time distribution. The Scan Statistics method was used in the first case and the Lomb-Scargle spectral analysis in the second case. The two techniques complete early analyses performed with "folding" methods. It is confirmed that the seasonal variation is the dominant periodic variation, and one also confirms the solar diurnal and sidereal modulations. A separate study concerns the analysis of the energy losses of the hypothetical Nuclearites in different materials and detectors; their importance for the searches performed by the MACRO and the SLIM experiments is discussed.

  14. Neuropsychologie et Neurolinguistique. Themes de recherche commune (Neuropsychology and Neurolinguistics. Themes of Common Research)

    ERIC Educational Resources Information Center

    Weigl, Egon; Bierwisch, Manfred

    1976-01-01

    By presenting preliminary results of joint experiments conducted by speech pathologists and linguists, this article discusses the possibility of further neuropsycholinguistic research. (Text is in French.) (CLK)

  15. Education Relative a l'Environnement: Regards, Recherches, Reflexions. Volume 4.

    ERIC Educational Resources Information Center

    2003

    This document takes a critical look at the relationship between environment, culture, and development from the perspective of education relative to the environment. Papers include: (1) "Education a l'environnement ou acculturation?" (Jean-Etienne Bidou); (2) "Environnement et developpement: La culture de la filiere ONU" (Lucie Sauve, Tom Berryman,…

  16. Recherche d'une nouvelle configuration de bobines supraconductrices pour le stockage d'énergie

    NASA Astrophysics Data System (ADS)

    Takorabet, M.; Mailfert, A.; Colteu, A.

    1998-04-01

    Energy storage using superconducting coils involves the problem of electromagnetic field pollution outside the considered system. Different configurations are widely studied: the torus, the alone solenoid and multiple parallel solenoids enclosed in one container. A new configuration which minimizes the external pollution is studied in this paper. The theoretical system is composed of two spherical distributions of the current which are concentric. The analytical study uses solution of Laplace equations. Parametric study covers energy, flux density and geometrical data. The second study concerns the numerical approach of this design using coaxial solenoids. A comparison between this new system and the known systems is presented as a conclusion. Le stockage d'énergie à l'aide de bobines supraconductrices soulève généralement le problème de la pollution électromagnétique par des champs de fuite extérieurs au dispositif. Différentes configurations ont été classiquement étudiées : le solénoïde, le tore, ainsi que les solénoïdes à axes parallèles non concentriques bobinés tête-bêche, en "fagot". Nous étudions ici une nouvelle configuration de stockage qui n'engendre qu'une pollution extérieure minimale. Le système théorique de base est constitué par l'association de deux distributions sphériques de courant concentriques. L'étude analytique que nous présentons s'appuie sur la résolution de l'équation de Laplace. L'étude de ce système couvre les données suivantes : l'énergie, l'induction ainsi que les données géométriques. On étudie aussi une configuration approchée de la configuration sphérique, constituée par des bobines circulaires. Une comparaison de ce système avec les solutions connues sera apportée en conclusion.

  17. [Role of the French Research Institute for Overseas Development (Institut de Recherche pour le Developpement, IRD)].

    PubMed

    Girard, Jean-François

    2008-02-01

    IRD is a French public scientific and technological institution, jointly overseen by the Ministries of Research and Overseas Cooperation. It has three main vocations: research, evaluation and training It meets these objectives by conducting scientific programs, centered around the relationship between humans and their environment in poor countries, in order to contribute to sustainable development. IRD has a budget of 218,9 millions euros. It employs 2 235 staff including 830 researchers, 1 021 engineers and technicians, and local personnel. Forty-two percent of IRD staff are employed overseas, many technicians originate from poor countries, and IRD research programs involve researchers from many countries. IRD is engaged in several European and international scientific programs, and plays a coordinating role for research institutions and universities working towards third-world development.

  18. Recherche universitaire et priorites nationales: l'effet du financement public sur la recherche energie solaire au Canada (University Research and National Priorities: The Effect of Public Financing on Solar Energy Research in Canada).

    ERIC Educational Resources Information Center

    Dalpe, Robert; Gingras, Yves

    1990-01-01

    The role of two main sources of university research financing in solar energy is examined to assess whether they oriented research in the direction of government programs. The strongest relationship appears to be in journal publication patterns. This scientific community has acquired the capacity to tap varying sources. (Author/MSE)

  19. Un corpus de francais parle. Montreal 84: Historique, methodes et perspectives de recherche (A Corpus of Spoken French. Montreal 84: History, Methods, and Perspectives of Research). Recherches Sociolinguistiques/1.

    ERIC Educational Resources Information Center

    Thibault, Pierrette; Vincent, Diane

    In 1984, a new corpus of spoken Quebecois French (Canada) was added to the existing data. In developing it, half of the native speakers participating in a 1971 study were re-interviewed, providing previously unavailable data on individual language development. The report describes in detail the sociolinguistic methodology used in developing the…

  20. Recherche du boson de Higgs standard dans le canal WH a l'experience D0 aupres du Tevatron

    SciTech Connect

    Lellouch, Jeremie

    2008-09-26

    The Higgs mechanism provides the Standard Model with an appropriate theory of the origin of the mass of gauge bosons and elementary fermions. The Higgs boson has not yet been discovered, but a lower limit on its mass has been set at 114.4 GeV at 95% con dence level by the Lep collaborations. Higgs searches are now being pursued at the Tevatron, a proton - anti-proton collider with a centreof- mass energy of 1.96TeV. At low mass the most sensitive channel is the associated production of a Higgs with a W boson. An analysis has been performed in the decay channel in which the Higgs goes into a b$\\bar{b}$ pair and the W decays to a muon and a neutrino with 1 fb-1 of Run IIa data recorded by the DØ detector. The analysis relies on all the sub-detector components but most particularly on the calorimeter which is essential for reconstruction of the b$\\bar{b}$ system. Good tracking and a b-identi cation neural network tool provide improved b-tagging performance which is crucial for this analysis. Because the energy resolution of jets is of paramount importance when hunting for a two-jet resonance bump, work has also been conducted on devising a better-performing calibration for jets which exhibit a muon and a neutrino in their fragmentation chain. The WH analysis is performed on a W+2 and W+3 jet event topology. Events containing a muon, missing transverse energy and two or three jets are selected; the jets are then b-tagged. The doubletagged and single-tagged channels are analysed separately so as to provide additional sensitivity. Signal-background separation via a neural network algorithme has furthermore been developed in the analysis in order to enhance sensitivity. This search for a standard Higgs boson has been conducted for Higgs masses ranging from 100GeV to 150GeV. Upper limits on production cross-section times branching ratio have been set. For a Higgs mass of 115GeV, the upper limit is set at 2.00 pb at 95% con dence level in the channel WH → μ b$\\bar{b}$ and 1.37 pb when combining the two channels WH → μ b$\\bar{b}$ and WH → e b$\\bar{b}$, which is to be compared to the theoretical prediction of 0.136 pb. Those results have been submitted for publication, and are used in the global combination of Cdf's and DØ's Higgs analyses.

  1. L'analyse des erreurs: etat actuel de la recherche (Error Analysis: Present State of Research). Errors: A New Perspective.

    ERIC Educational Resources Information Center

    Lange, Michel

    This paper raises questions about the significance of errors made by language learners. The discussion is divided into four parts: (1) definition of error analysis, (2) the present status of error analysis research, including an overview of the theories of Lado, Skinner, Chomsky, Corder, Nemser, and Selinker; (3) the subdivisions of error analysis…

  2. Apercu de certains developpements recents des recherches sur l'acquisition du langage (Recent Developments in Language Acquisition Research)

    ERIC Educational Resources Information Center

    Berthoz-Proux, Michelle

    1975-01-01

    The goal of this article is to give a survey of the literature and theoretical trends relevant to language acquisition. Developments in the fields of psychology, psycholinguistics, sociology, sociolinguistics and in various interdisciplinary studies are discussed. (Text is in French.) (CLK)

  3. Towards Evidence-Based Policy for Canadian Education = Vers des politiques candiennes d'education fondees sur la recherche.

    ERIC Educational Resources Information Center

    De Broucker, Patrice, Ed.; Sweetman, Arthur, Ed.

    This book is a collection of 19 essays that broadly treat the use of evidence in informing educational policy and practice in Canada: (1) "Knowledge and Action in Educational Policy and Politics" (Benjamin Levin); (2) "Data, Data Everywhere (and We Don't Know What to Do): Using Data for Wise Decisions in Schools" (Lorna M.…

  4. A la recherche d'un apprentissage d'orientation (In Search of an Appropriate Second Language Learning Experience).

    ERIC Educational Resources Information Center

    Jacobs-Hessing, Noortje; Maleville, Mireille

    1983-01-01

    There has been much discussion about the role of foreign languages, particularly French, in Netherlands secondary education reform. Any attempt to redefine objectives and learning approaches must consider social, political, educational, and linguistic influences. Most weight should be given to affective factors but new trends must be approached…

  5. La composition chimique de l'aerosol atmospherique de Yaounde (Cameroun)—recherche de ses sources

    NASA Astrophysics Data System (ADS)

    Pélassy, Pierre

    This is a study about the chemical components of the atmospheric aerosol daily collected at Yaoundé (Cameroon) during a complete seasonal cycle between March 1976 and April 1977. Nine elements were investigated (Al, Ca, Fe, K, Mg, Mn, Na, Si and Ti). Their monthly concentrations and statistical characteristics are given. The correlations between these elements taken by pairs are being evaluated to give a first idea of their origins. Finally, there is an evaluation of the aerosol-crust enrichment factors with the Al taken as a reference including a detailed examination of scatter diagrams established vs the same element. As a conclusion, an attempt is made to assess the importance of the crustal and non-crustal components for the elements which obviously have several sources.

  6. [The Association de recherche en soins infirmiers: a story of combination of circumstances, a strong axis and encounters].

    PubMed

    Jovic, Ljiljana

    2015-06-01

    Research in Nursing has grown significantly in France. The usefulness and necessity of scientific research, to provide quality care, and its role in the professionalization are now accepted. The Nursing Research Association (Arsi) is a key player contributing for over thirty years to the development and recognition of research as a means to develop and acquire knowledge, and to base care on Scientifics data. Established in 1983 Arsi is a combination of circumstances of history, a major focus, objectives and encounters with people who identified the interest of research in nursing and supported the associations initiatives. Its characteristic is to have been able to balance cares 'need, research, and to put itself in a prospective dimension. Today, the association is recognized nationally and internationally for the quality of its work and its contribution to the development of research and nursing sciences. This recognition is the result of a continous and demanding work of many volunteers committed to support the objectives of the association.

  7. Machines a Comprendre la Parole: Methodologie et Bilan de Recherche (Automatic Speech Recognition: Methodology and the State of the Research)

    ERIC Educational Resources Information Center

    Haton, Jean-Pierre

    1974-01-01

    Still no decisive result has been achieved in the automatic machine recognition of sentences of a natural language. Current research concentrates on developing algorithms for syntactic and semantic analysis. It is obvious that clues from all levels of perception have to be taken into account if a long term solution is ever to be found. (Author/MSE)

  8. Chandra: un observatoire de rayons X à la recherche de gaz très chaud et de trous noirs

    NASA Astrophysics Data System (ADS)

    Mamon, Gary A.

    2002-09-01

    Pour le grand public, les rayons X sont généralement associés à la possibilité de vision radiographique des objets en absorption. Mais pour l'astronome, les rayons X permettent d'observer en émission 1) le gaz très chaud, de l'ordre de 5 à 100 millions de degrés autour des galaxies, entre les galaxies dans les grands groupes et amas, et à l'intérieur des galaxies lors d'explosions d'étoiles en supernovae; 2) le gaz très fortement magnétisé autour des étoiles à neutrons et trous noirs.

  9. Phonetique corrective et methodologie de la recherche du systeme des fautes (Corrective Phonetics and Research Methodology of Error Patterns)

    ERIC Educational Resources Information Center

    Lebrun, Claire

    1976-01-01

    This article analyzes three studies undertaken to scientifically define error patterns, and outlines a methodology for investigating them. The studies concern native English speakers learning French. (Text is in French.) (CLK)

  10. Machines a Comprendre la Parole: Methodologie et Bilan de Recherche (Automatic Speech Recognition: Methodology and the State of the Research)

    ERIC Educational Resources Information Center

    Haton, Jean-Pierre

    1974-01-01

    Still no decisive result has been achieved in the automatic machine recognition of sentences of a natural language. Current research concentrates on developing algorithms for syntactic and semantic analysis. It is obvious that clues from all levels of perception have to be taken into account if a long term solution is ever to be found. (Author/MSE)

  11. Recherches en phonetique et en phonologie au Quebec (Research in Phonetics and Phonology in Quebec). Publication B-206.

    ERIC Educational Resources Information Center

    Dolbec, Jean, Ed.; Ouellet, Marise, Ed.

    The collection of essays on phonetics and phonology, entirely in French, includes: "Le calcul de la frequence intrinseque. Necessite du rapport a une ligne de reference" (calculation of intrinsic frequency; necessity of a line of reference) (Conrad Ouellon); "Caracteristiques microprosodiques de duree et d'intensite en lecture et en…

  12. Achete grilles et methodes pour recherche d'idees sans peine (Buy Grids and Painless Methods for Finding Ideas).

    ERIC Educational Resources Information Center

    Yaiche, Francis

    1986-01-01

    Proposes tools and methods for teachers and students to use in the classroom to organize and stimulate ideas, imagination, memory, improvisation, and writing. Sample outlines and grids serve as methods for helping learners understand specific concepts. (MSE)

  13. Achete grilles et methodes pour recherche d'idees sans peine (Buy Grids and Painless Methods for Finding Ideas).

    ERIC Educational Resources Information Center

    Yaiche, Francis

    1986-01-01

    Proposes tools and methods for teachers and students to use in the classroom to organize and stimulate ideas, imagination, memory, improvisation, and writing. Sample outlines and grids serve as methods for helping learners understand specific concepts. (MSE)

  14. Towards Evidence-Based Policy for Canadian Education = Vers des politiques candiennes d'education fondees sur la recherche.

    ERIC Educational Resources Information Center

    De Broucker, Patrice, Ed.; Sweetman, Arthur, Ed.

    This book is a collection of 19 essays that broadly treat the use of evidence in informing educational policy and practice in Canada: (1) "Knowledge and Action in Educational Policy and Politics" (Benjamin Levin); (2) "Data, Data Everywhere (and We Don't Know What to Do): Using Data for Wise Decisions in Schools" (Lorna M.…

  15. Recherches en Dialectologie Franco-Ontarienne. (Research in Franco-Ontarian Dialectology.) Working Papers on Bilingualism, No. 14.

    ERIC Educational Resources Information Center

    Canale, Michael; And Others

    This study examines the use of the auxiliaries "avoir" and "etre" and of the prefix "re-" in the speech of Franco-Ontarian students. It is found that the tendency to use non-standard constructions such as "j'ai arrive en retard" and "je vais remettre la roue 'back'" has its origins in historical…

  16. Summary of Research Findings on Children's Developmental Health = Resume des conclusions de la recherche sur la sante developpementale des effants.

    ERIC Educational Resources Information Center

    Bertrand, Jane

    This kit is comprised of bilingual resources for child caregivers related to nourishing and nurturing a child's brain for optimal neurodevelopmental health. The kit is the result of a 30-month project to synthesize research on brain development and to develop resources in support of excellent caregiver practice in Canada. The kit contains the…

  17. Recherche de charginos et neutralinos dans le canal dimuon de meme signe aupres de l'experience DØ - FNAL

    SciTech Connect

    Lesne, Vincent

    2006-07-01

    Dans le cadre du modele mSUGRA qui decrit un mecanisme de brisure simple de la supersym etrie, des sparticules avec des masses au-del a des limites fixees par les experiences de LEP II peuvent etre produites au Tevatron, collisionneur p$\\bar{p}$ delivrant une energie de 1.96 TeV dans le centre de masse. Un canal privilegie pour la d´ecouverte de la supersymetrie au Tevatron est la production associee du plus leger chargino, $\\tilde{χ}$$±\\atop{1}$ , et du second plus leger neutralino, $\\tilde{χ}$$0\\atop{2}$ . Les modes de desintegration leptoniques, $\\tilde{χ}$$0\\atop{2}$ → $\\tilde{χ}$$0\\atop{1}$ ℓ+- et $\\tilde{χ}$$±\\atop{1}$ → $\\tilde{χ}$$0\\atop{1}$ ℓ±νl, conduisent a une signature claire avec trois leptons et un quantite significative d’energie transverse manquante.

  18. Hydraulische Optimierung des Reaktionsraumes um einen Infiltrationsbrunnen zur unterirdischen Enteisenung - Feldversuche und numerische Simulation zur Planung der optimalen Verfahrensergiebigkeit (Teil 1/2)

    NASA Astrophysics Data System (ADS)

    Ahrns, Johannes; Bartak, Rico; Grischek, Thomas; Pörschke, Richard

    2017-08-01

    In subsurface iron removal (SIR), oxygen-enriched water is injected into an aquifer to create a reaction zone. Aside from the hydraulic properties of the aquifer, groundwater quality often varies with depth so that in vertical wells the dissolved oxygen distribution (reaction zone) may not correspond to the dissolved iron concentration which may result in a lower efficiency coefficient. Therefore, measures to hydraulically optimize the formation of the reaction zone through a non-conventional injection were investigated. A high-resolution groundwater flow model was calibrated based on tracer and pump tests and used to plan the optimized injection for a SIR-pilot well with two screen segments. An optimized injection appears to be possible through the inactivation of well screen sections using packers. A doubling of the efficiency coefficient in comparison to a conventional injection was predicted when a packer, which remains evacuated inside the well while pumping, was used to seal 4/5 of the upper well screen length during injection. This scenario was used to plan the operating regime for a SIR field test, which is presented in Part 2.

  19. Evaluation in medical education: A topical review of target parameters, data collection tools and confounding factors.

    PubMed

    Schiekirka, Sarah; Feufel, Markus A; Herrmann-Lingen, Christoph; Raupach, Tobias

    2015-01-01

    Hintergrund und Fragestellung: Die Evaluation ist fester Bestandteil der Lehre an Medizinischen Fakultäten. Gemäß den Standards der Deutschen Gesellschaft für Evaluation müssen Evaluationsinstrumente eine faire und genaue Beurteilung der Lehrqualität erlauben. Entsprechend müssen die genutzten Erhebungsinstrumente eine hohe Reliabilität und Validität aufweisen. In dieser Übersichtsarbeit wird die verfügbare Literatur zur Evaluation des Medizinstudiums mit Hinblick auf die möglichen Dimensionen der Lehrqualität, die psychometrischen Eigenschaften der Instrumente und potentielle Störfaktoren dargestellt.Methoden: Ausgehend von einer Schlagwortsuche in Pubmed, PsycINFO und PSYNDEX wurde eine Literatur-Recherche zur Evaluation im Medizinstudium durchgeführt. Berücksichtigung fanden Arbeiten, die bis zum 30.6.2011 in die Datenbanken aufgenommen wurden sowie „graue Literatur“. Die Ergebnisse werden in narrativer Form präsentiert.Ergebnisse: Es wurden vier Dimensionen der Lehrqualität im Medizinstudium identifiziert: Strukturen, Prozesse, Dozenten-Charakteristika und das Lehr-Ergebnis. Zur Betrachtung der ersten drei Dimensionen werden in erster Linie studentische Bewertungen herangezogen. Hierfür liegen einige reliable, in deutscher Sprache verfügbare Instrumente vor. Die Validität studentischer Bewertungen wird jedoch durch zahlreiche potentielle Störfaktoren eingeschränkt. Zur Beurteilung des Lehr-Ergebnisses werden vor allem Prüfungsleistungen herangezogen, deren Nutzbarkeit allerdings aufgrund methodischer Probleme eingeschränkt sein kann. Zudem genügen nicht alle Prüfungen an deutschen medizinischen Fakultäten den gängigen Qualitätsstandards.Folgerung: Die Auswahl von Instrumenten zur Evaluation des Medizinstudiums sollte sich daran orientieren, welche Dimension der Lehre beurteilt werden soll. Entsprechend können Evaluationsergebnisse auch nur vor dem Hintergrund des vom genutzten Erhebungsinstrument abgebildeten Konstrukts und

  20. Naturwissenschaftliche Methoden zur Beurteilung von Gemälden und Graphik

    NASA Astrophysics Data System (ADS)

    Kühn, Hermann

    1983-09-01

    Stylistic criteria are sometimes not sufficient in order to differentiate with certainty between copies or fakes and originals. Analyses of paints, supports and artistic technique may give an indication for the earliest possible date of a painting or a work of graphic arts. For example, supports made from oak, fir, spruce and beech can be dated by yearring analysis (dendrochronology). Exclusively methods on micro and ultramicro scale are suitable for the identification of various materials, i.e. microchemistry, emission spectrographic analysis, X-ray powder diffraction because only very tiny samples can be taken from the object.

  1. Generierung korrespondierender Schichtbilder zur verbesserten lokalen Analyse des linken Ventrikels in 4D-MRT-Bildsequenzen

    NASA Astrophysics Data System (ADS)

    Säring, D.; Müllerleile, K.; Groth, M.; Handels, H.

    Die genaue Erfassung lokaler Veränderungen des linken Ventrikels insbesondere bei der Verlaufskontrolle nach einem Infarkt erfordert die Extraktion lokaler Form- und Funktionsparameter. Die für den Inter- und Intrapatientenvergleich notwendige räumliche Korrespondenz der MRT-Schichtbilder ist durch die manuelle Planung der Schichtpositionen beim Aufnahmeverfahren i.A. nicht gewährleistet. In dieser Arbeit wird daher ein Verfahren vorgestellt, das unter Berücksichtigung der anatomischen Grenzen des linken Ventrikels räumlich korrespondierende Positionen bestimmt, zu denen anschließend unter Verwendung der originären Daten und der strukturerhaltenden Interpolation neue Schichtbilder generiert werden. Dadurch wird eine bessere Übereinstimmung der räumlichen Position der zu vergleichenden Schichten erzielt. Das Verfahren wurde an zu Evaluationszwecken generierten Probandendatensätzen getestet. Dabei konnte gezeigt werden, dass die Generierung korrespondierender Kurzachsen-MRT-Schichtbilder zu einer verbesserten Extraktion lokaler Parameter führt.

  2. Zur ethischen Dimension von Renaturierungsökologie und Ökosystemrenaturierung

    NASA Astrophysics Data System (ADS)

    Ott, Konrad

    Die wissenschaftlich angeleitete Ökosystemrena-turierung kann mittlerweile als eine etablierte Praxis im Bereich des Naturschutzes gelten. Diese Praxis bezieht sich notwendigerweise auf Ziele und Werte und weist damit auch eine naturethische Dimension auf. Daher hat diese Praxis die Aufmerksamkeit auch von Sozialwissenschaftlern und Ethikern auf sich gezogen. Dieses Kapitel geht der Frage nach, wie sich die naturethische Dimension der Ökosystemrenaturierung analysieren und inhaltlich bestimmen lässt. Hierzu erweist sich auch die Auseinandersetzung mit Philosophen als hilfreich, die der Ökosystemrenaturierung ein technizistisches Naturverständnis vorgeworfen haben. Am Ende des Kapitels wird ein in sich gestuftes mögliches naturethisches Selbstverständnis der Ökosystemrenaturierung diskutiert, das den an dieser Praxis Beteiligten Freiheitsgrade der Positionierung belässt.

  3. Zur Soziolinguistik in der Bundesrepublik Deutschland (Sociolinguistics in the Federal Republic of Germany)

    ERIC Educational Resources Information Center

    Jachnow, Helmut

    1975-01-01

    Traces the history of sociolinguistic studies in West Germany from the early nineteenth century with Humboldt and reports on the state and purposes of sociolinguistic studies in present-day Federal Republic of Germany. Available from Liber Laeromedel, Box 1205, S-22105 Lund, Sweden (Text is in German.) (TL)

  4. Verfahren zur Analyse klimatischer und anthropogener Einflüsse auf die Grundwasserstandsentwicklung

    NASA Astrophysics Data System (ADS)

    Wriedt, Gunter

    2017-03-01

    Limitations in applying the Wiener-Multichannel filter to analyze anthropogenic influences on groundwater level dynamics require a new approach independent from reference observation wells. This article presents a simple approach to analyze the relation between groundwater elevations and climate parameters for groundwater monitoring wells. A theoretical "climatic groundwater level series" is derived from monthly climatic water balances considering the transforming effects of the unsaturated zone and local conditions on groundwater level dynamics. Comparing theoretical groundwater levels with observed groundwater level fluctuations allows analyzing the agreement with the temporal dynamics of climatic parameters as well as detecting possible anthropogenic influences. A total of 284 of 573 groundwater observation wells in Lower Saxony show natural groundwater level dynamics, while artificial impacts were found in 221 wells and 68 wells remain unclear. A classification was therefore possible for 88% of the wells. A high model performance was detected for wells without artificial impacts and with minor artificial impacts. A split-sample cross validation proves the predictive capacity of the model for wells with natural dynamics.

  5. Abstract and review of "Zur Erbpathologie der Schizophrenie" (Contribution to the genetics of schizophrenia). 1916.

    PubMed

    Kendler, K S; Zerbin-Rüdin, E

    1996-07-26

    Starting from the 722 probands originally studied by Rüdin, Bruno Schulz re-examined them and their relatives confirming the diagnosis in 660. While Rüdin sought for mendelian ratios in siblings, Schulz, anticipating modern methods, focused on the family study method as an approach to clarifying possible etiologic heterogeneity within the schizophrenia syndrome. Using a Kraepelian approach to diagnosis, Schulz reports a MR for narrowly and broadly defined schizophrenia of 6.7 and 8.2% in siblings and 2.6 and 3.7% in parents. He found no evidence for a difference in risk of illness in siblings as a function of either the gender or outcome of the proband. The risk for schizophrenia was significantly increased in siblings of hebephrenic probands. Compared to siblings of probands with no identified factor which precipitated their schizophrenia, the risk for schizophrenia was significantly decreased in probands with a physical etiologic factor but did not differ in siblings of probands with a psychological etiologic factor. The risk for schizophrenia was particularly low in siblings of probands whose onset of illness occurred within a year of major head trauma.

  6. Zur Variabilität einiger heißer Sterne im Orionnebel.

    NASA Astrophysics Data System (ADS)

    Rößiger, S.

    Recent photoelectric UBV observations obtained by the author during the years 1981 to 1985 confirm the result of Kardopolov that the early-type stars KX, LP, NU, V359, V361 and V372 Orionis in the Orion nebula show brightness constancy within the observational errors. The same holds for the stars KS and LZ Orionis.

  7. Einstein's contribution to cosmology - an overview (German Title: Einsteins Beitrag zur Kosmologie - ein Überblick)

    NASA Astrophysics Data System (ADS)

    Jung, Tobias

    It is well known that Einstein founded relativistic cosmology in 1917 when he published his ``Cosmological considerations in the general theory of relativity.'' He presented a static, spatially closed though unbounded cosmological model with a uniform large-scale distribution of matter. For more than a decade, he defended his Einstein model against the proposals of Friedmann (1922/23) and Lemaître (1927) who took non-static world models into consideration, as well as against the spatially infinite model worked out by Selety (1922). Only after getting acquainted with the latest observational data like Hubble's redshift-distance relation during visiting Hubble, Tolman and others in California around the turn of the year 1930, Einstein gave up his static model and began to accept expanding world models. In the aftermath, he himself proposed two expanding world models, namely the Friedmann-Einstein universe in 1931 and the Einstein-de Sitter universe in a joint paper with de Sitter in 1932. In Einstein's opinion, world models still had to be spatially closed, but the cosmological constant which he had introduced in 1917 to obtain a static cosmological model had to be abandoned. In his later years, Einstein showed scepticism against relativistic cosmology as can be seen from his remarks concerning the rotating Gödel universes (1949). Although Einstein seemed to consider relativistic cosmology as a ``fashionable disease'' the then discovered Friedmann-Lemaître models are still used to describe the large-scale evolution of the space-time background of the universe.

  8. Zur Biogeographie des Südwestatlantik mit besonderer Berücksichtigung der Seeanemonen (Coelenterata: Actiniaria)

    NASA Astrophysics Data System (ADS)

    Riemann-Zürneck, Karin

    1986-03-01

    Extensive sampling of benthos by F.R.V. “Walther Herwig” (1966, 1970/71, 1978) covering the continental shelf of Argentina yielded some 1000 sea anemone specimens (19 species). The distribution patterns of the sublittoral and archibenthal species are analysed and compared with the rather scanty and controversial hydrographical information available. Species with discontinuous distribution along the continental shelf edge are believed to indicate discontinuous yet relatively stable oceanographic conditions within the depth concerned. The archibenthal “Challenger Terrace”, located immediately near and beneath the subtropical convergence, harbours a peculiar faunal assemblage of partly subantarctic/antarctic character and partly consisting of species which seem to be typical for permanent hydrographic fronts. In addition, the study includes a new taxonomic combination: Bolocera tuediae subsp. kerguelensis (Studer, 1879) nov. comb.

  9. SURFACTANT-ENHANCED EXTRACTION TECHNOLOGY EVALUATION VERSUCHSEININCHTUNG ZUR GRUNDWASSER-UND ALTLASTENSANIERUNG (VEGAS) FACILITY, STUTTGART, GERMANY

    EPA Science Inventory

    This innovative technology evaluation report (ITER) summarized the results of an evaluation of a surfactant-enhanced extraction technology. This evaluation was conducted under a bilateral agreement between the United States (U.S.) Environmental Protection Agency (EPA) Superfund ...

  10. Sind die klassischen Methoden zur mykologischen Diagnostik noch "State-of-the-Art"?

    PubMed

    Wiegand, Cornelia; Bauer, Andrea; Brasch, Jochen; Nenoff, Pietro; Schaller, Martin; Mayser, Peter; Hipler, Uta-Christina; Elsner, Peter

    2016-05-01

    Die Labordiagnose einer Pilzinfektion der Haut basiert traditionell auf dem Nativpräparat und der Anzucht des Erregers aus dem klinischen Material. Auch der dermato- histologischer Nachweis von Pilzelementen ist möglich. Diese Methoden sind, sofern sie korrekt ausgeführt werden, in der Regel zum Pilznachweis geeignet. Im Zuge der personalisierten Medizin und den daraus erwachsenden Aufgaben werden jedoch neue Verfahren erforderlich, welche einfach, spezifisch und schnell sind. Der zusätzliche Einsatz von DNA-basierten molekularen Methoden erhöht die Empfindlichkeit sowie die diagnostische Spezifität und reduziert die zum Teil wochenlange Durchführungszeit der konventionellen mykologischen Diagnostik auf 24 bis 48 Stunden. Im Zuge der stetigen Weiterentwicklung im Bereich der personalisierten Medizin sind einfache Analysensysteme auf PCR-Basis denkbar, die in der Hautarztpraxis eine Dermatophyten-Sofort-Diagnostik erlauben (Point-of-Care-Tests). © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  11. Reforms and Innovations in Estonian Education. Baltische Studien zur Erziehungs- und Sozialwissenschaft. Volume 16

    ERIC Educational Resources Information Center

    Mikk, Jaan, Ed.; Veisson, Marika, Ed.; Luik, Piret, Ed.

    2008-01-01

    This collection of papers provides a small overview of educational research in Estonia. The papers in the collection treat school reforms since the renewal of independence in 1991, new approaches to teacher training, the implementation of a child-centred approach in school, the achieving of educational aims and other actual topics in education.…

  12. Zur Determination der zeitlichen Verteilung von Fortpflanzungsprozessen in Laborkulturen des Polychaeten Typosyllis prolifera

    NASA Astrophysics Data System (ADS)

    Franke, H.-D.

    1980-03-01

    Factors controlling the timing of reproduction in laboratory cultures of the polychaete Trposyllis prolifera. Typosyllis prolifera (Krohn) from Poreč (Yugoslavia) has been cultured for 12 successive generations. The life cycle of the species in the laboratory is described briefly. During their life individuals reproduce several times (up to 15) by stolonization which, under constant laboratory conditions (LD 16:8, 20 °C), is cyclic and takes place about every 30 days. Based on the investigations of Durchon (1959) and Wissocq (1966), experiments on extirpation and transplantation of the proventriculus have been carried out. The results suggest that an endocrine system anatomically connected to the proventriculus is important in the control of reproduction. Most likely, the endogenous reproductive cycle of an individual is controlled by periodical changes of the activity of this system. During the period following stolonization, the endocrine system of the proventriculus, which at this time shows its maximal activity, inhibits sexual development and enables regeneration of the segments lost as stolon. A subsequent decrease of the hormonal activity induces sexual maturation and epitokous metamorphosis, thus leading to further stolonization. Exogenous factors influencing the timing of reproduction probably affect the endocrine function of the proventriculus. Short-day photoperiods (LD 10:14) and low temperatures (12 °C) given simultaneously (i.e. winter conditions) totally suppress reproduction. Under normally favourable conditions (LD 16:8, 20 °C), reproductive processes can be prevented by starving or amputation of caudal segments. In all these cases, however, stolonization can be induced by removing the proventriculus. Exogenous factors also play a decisive role in synchronizing reproductive events within the species population. Under field conditions reproduction shows a lunar periodicity. The endogenous reproductive cycles of cultured specimens can be synchronized by a periodical light regime simulating the change of the moon.

  13. Numerische Szenariosimulationen zur Ausbreitung von hochmineralisiertem Wasser in oberflächennahen Süßwasseraquiferen

    NASA Astrophysics Data System (ADS)

    Wiegers, Carla Elisabeth; Schäfer, Dirk

    2015-06-01

    In areas where the geological subsurface is used for storage of gases or fracking, there is a risk of saline formation water entering protected aquifers. The impact of such potential leakage therefore needs to be evaluated at relevant sites to develop practical monitoring concepts. Three-dimensional numerical simulations and a sensitivity analysis are performed to determine the influence of aquifer parameters, ground water flow, aquifer morphology, leakage rate and NaCl-concentration of the intruding water on the propagation behaviour of saline water. Two example scenarios were simulated based on a realistic site-scale conceptual model, one with water from the lower Braunkohlensande, (NaCl = 7.61 g/l) the other with saline water from the Bunter sandstone formation (NaCl = 280.3 g/l). The simulations show that saltwater migrates along the bottom of the aquifer, and that groundwater flow can dominate the transport of chloride. In this case the spreading of denser water is not influenced by the aquifer's morphology.

  14. Lifelong Learning: One Focus, Different Systems. Studien zur Erwachsenenbildung, Band 19.

    ERIC Educational Resources Information Center

    Harney, Klaus, Ed.; Heikkinen, Anja, Ed.; Rahn, Sylvia, Ed.; Schemmann, Michael, Ed.

    These 17 articles on different subjects of the broader theme "lifelong learning" represent the latest results of the discussions of the Vocational Education and Culture Research Network. An introduction (Klaus Harney et al.) provides summaries of the contents. The articles are "The Global and International Discourse of Lifelong…

  15. Bemerkungen zu den Pronominaladverbien und zur Pronominalitaet (Notes on Pronominal Adverbs and Pronominalness)

    ERIC Educational Resources Information Center

    Helbig, Gerhard

    1974-01-01

    Calls "pro-words" those which refer to a preceding substantive. They are (1) pronouns, (2) pronominal adverbs - "dadurch,""hiermit,""wofur," etc., and (3) pro-adverbs - "dort,""dann," etc. Both (2) and (3) stand for combinations of preposition plus preceding substantive; (3) does this only semantically, while (2) marks the relation overtly. (Text…

  16. Zur Entwicklung des qualitativen Adverbs im Deutschen (On the Development of the Qualitative Adverb in German)

    ERIC Educational Resources Information Center

    Paraschkewoff, Boris

    1974-01-01

    The contemporary German, predicate adjective and adjectival adverb are expressed by the same form. Although modern grammatical research gathers the various functions of the adjective under "indicator of kind," school practice still separates adjective and adverb. The historical development of qualitative adverbs is outlined. (Text is in German.)…

  17. Vergleich unterschiedlicher Methoden zur Entnahme von Feststoffproben für mikrobielle Untersuchungen

    NASA Astrophysics Data System (ADS)

    Scheytt, Traugott; von Freyberg, Jana

    2015-12-01

    Sediment sampling for microbial characterization is often associated with cross-contamination. The aim of this study was to assess the suitability of widely used sediment-sampling techniques for obtaining microbially uncontaminated samples from the saturated zone. Three different methods were applied: Continuous percussion drilling, discontinuous drilling with Direct-Push technology and a freeze corer using liquid nitrogen for cooling. Microbial contamination was monitored with dye tracers and fluorescent micro beads. It was assumed that microbial contamination would take place mainly at the ground surface. The results show that the sediment cores in the liners from both the conventional core driver and from Direct-Push yielded little to no contamination if the uppermost 30 cm and the outer part of the sediment core were discarded. A broken core resulted in a high degree of contamination. The freeze corer did not meet the expectations and lead to unsatisfactory results.

  18. Leonard Cohen: Suzanne. Kritische Anmerkungen zur Interpretation (Critical Comments on Interpretation)

    ERIC Educational Resources Information Center

    Faulstich, Werner

    1977-01-01

    Criticizes a critique by J. Marsden of Leonard Cohen's pop song "Suzanne" as material for high school foreign language teaching. States that Marsden's article is concerned only with the text. The music agrees with the theme (loneliness) and with the "social milieu." (Text is in German.) (IFS/WGA)

  19. Ein Entscheidungsmodell zur Weitergabe persönlicher Daten im Internet

    NASA Astrophysics Data System (ADS)

    Treiblmaier, Horst

    In den vergangenen zwei Jahrzehnten wandelte sich das Internet von einer Spielwiese für technikbegeisterte Computerspezialisten zu einem vielseitig einsetzbaren weltweiten Netzwerk für Privatpersonen und Unternehmen. Maßgeblichen Anteil daran besaß die rasante Entwicklung des World Wide Web (WWW), das, durch die Möglichkeit multimediale Inhalte zu vermitteln, für einen großen Teil der Bevölkerung industrialisierter Länder zu einem wesentlichen Bestandteil des täglichen Lebens wurde. Dass diese Entwicklung noch lange nicht abgeschlossen ist, zeigt die derzeitige Diskussion zum Thema Web 2.0 bzw. 3.0. Waren es in den letzten Jahren die hohen Umsatzzuwächse im E-Commerce und multimedial gestaltete Webseiten in Kombination mit aufwändigen Applikationen, die für ständig steigende Nutzerzahlen im World Wide Web sorgten, so wird dieser Innovationsschub nunmehr durch eine Vielzahl von Anwendungen fortgesetzt, die sich durch die zunehmende Vernetzung der Nutzer untereinander auszeichnen.

  20. Eine Beziehung seit 650 Jahren: Universität Wien und Kloster Melk - Katalog zur Sonderausstellung

    NASA Astrophysics Data System (ADS)

    Bruckmüller, Ernst; Niederkorn-Bruck, Meta; Beck, Paul G.; Deibl, Jakob; Deibl, Johannes; Denk, Ulrike; Ellegast, Burkard; Floßmann, Gerhard; Glaßner, Gottfried; Kalteis, Bernadette; Kowarik, Wilfried; Rotheneder, Martin

    2015-04-01

    University of Vienna was founded in 1365 and celebrates its 650 anniversary in 2015. Due to the university's anniversary, the Benedictine abbey of Melk, Austria presents an exhibition, depicting six and half centuries of university history and collaboration between the university as well as the abbey in all disciplines present at medieval universities. The publication describes the historic frame work as well as case-by-case descriptions of displayed manuscripts, prints and artifacts. Die Universität Wien wurde 1365 gegründet und feiert 2015 ihr 650jähriges Bestehen. Aus Anlass dieses Jubiläums präsentiert das Benediktiner Stift Melk eine Ausstellung, in der sechseinhalb Jahrhunderte Universistaetsgeschichte aufgearbeitet werden, sowie die Zusammenarbeit zwischen Universität und Abtei auf allen Themenbereichen, die an mittelalterlichen Universitäten angeboten wurden. Die Publikation bietet eine historische Zusammenfassung sowie eine Detailbeschreibung der ausgestellten Handschriften, Drucke sowie Gegenstände.

  1. Zur Hydrogeologie veränderlich fester Gesteine mit Sulfatgestein, Beispiel Gipskeuper (Trias, Grabfeld-Formation)

    NASA Astrophysics Data System (ADS)

    Ufrecht, Wolfgang

    2017-09-01

    In the Southwest German Cuesta, the 150-metre-thick Gipskeuper-Formation (Grabfeld-Formation, Triassic) is dominated by claystones, intercalated with dolostone beds and thin- to massive-bedded sulfate rocks. When in contact with groundwater, the soft claystones experience a reduction of rock strength in several weathering stages. Upon hydration of anhydritic sulfates, the resulting gypsum is also subject to leaching. As both processes are dependent on depth and geomorphological relief, complex aquifer geometries with a high range of hydraulic properties develop. In extreme cases, impermeable, low-permeability and high-permeability zones can be found contiguously within the Gipskeuper. The process of aquifer evolution is described using the example of the Stuttgart basin.

  2. Reforms and Innovations in Estonian Education. Baltische Studien zur Erziehungs- und Sozialwissenschaft. Volume 16

    ERIC Educational Resources Information Center

    Mikk, Jaan, Ed.; Veisson, Marika, Ed.; Luik, Piret, Ed.

    2008-01-01

    This collection of papers provides a small overview of educational research in Estonia. The papers in the collection treat school reforms since the renewal of independence in 1991, new approaches to teacher training, the implementation of a child-centred approach in school, the achieving of educational aims and other actual topics in education.…

  3. Mikrosensor-gesteuerte Rückkopplungs- Bioaktuatoren auf Halbleiterbasis zur biophysikalischen Krebsbehandlung

    NASA Astrophysics Data System (ADS)

    Wolf, Bernhard; Kraus, Michael

    Acidic microenvironmental conditions combined with large hypoxic areas are ubiquitous hallmarks of most solid tumors. They result from a poorly organized vascularization and a deviant energy metabolism. There is convincing evidence supporting the hypothesis that such physico-chemical conditions promote the microevolution of malignant cells, inhibit the cellular immune response, and favor tumor cell invasion. In agreement with published data, our cell biological analyses and computer simulations indicate that treatment schemes which restore a tumor microenvironment reflecting that one found in normal tissues might improve the efficiency of immunotherapies and classical methods for cancer treatment. We suggest that the tumor microenvironment could be effectively monitored and manipulated by means of silicon-based feedback bioactuators which are controlled by integrated microsensors. In principle, miniaturized bioactuators can be implanted directly at the sites of inoperable tumors and metastases where they function as a 〝pH clamp'' and thereby can reconstitute normal physico-chemical conditions. Drug application could be precisely controlled by an integrated microprocessor. Our paper summarizes the current state of development of microsensor-based feedback bioactuators and outlines possible applications in biophysical cancer treatment.

  4. Zur Didaktik der medizinischen Fachsprache (On Teaching the Technical Language of Medicine)

    ERIC Educational Resources Information Center

    Becker, Norbert

    1974-01-01

    This guide is designed for teaching Spanish-speaking students of medicine who are learning to read highly specialized texts in their field. A sample text, of seven lines, is presented, followed by a carefully worked out teaching plan, exercises, and a test. (Text is in German.) (IFS/WGA)

  5. Rear-Guard Actions against an "Impoverishing Delusion": Anmerkungen zur Situation der Auslandsgermanistik in den Americas

    ERIC Educational Resources Information Center

    McCarthy, John A.

    2010-01-01

    This contribution responds to the previous three articles by highlighting common concerns across the Americas. It also offers suggestions for how the field of German might want to move forward in an inclusive fashion. Key principles of orientation are EU language policy and transcultural education as a transformative experience in shaping…

  6. Von den Flitterwochen zur distanzierten Partnerschaft. Deutsche Manager in internationalen M&A

    NASA Astrophysics Data System (ADS)

    Fuchs, Martina; Schalljo, Martin

    2017-04-01

    Cross-border mergers and acquisitions (M&A) require considerable intercultural openness on the part of the managers involved. A recent wave of takeovers by private equity investors and foreign investors from emerging economies has challenged German executives. In cases of friendly takeovers, as described in this study, managers at first appear to extend a cosmopolitan welcome to the new owners. However, further analysis of structural hermeneutics reveals latent normative professional ethics of managers which lead to practices of distancing, in particular from young investors from China, India, and Russia.

  7. Untersuchungen zur Sorptionsreversibilität von organischen Schadstoffen in Aktivkohle, Holzkohle und Zeolith Y-200

    NASA Astrophysics Data System (ADS)

    ElHaddad, Engy; Ensinger, Wolfgang; Schüth, Christoph

    2013-09-01

    Numerous studies have shown that sorption of organic contaminants in soils is dominated by the natural organic carbon content ( C org) of the soil. However, it is still under discussion whether sorption processes are fully reversible or whether an irreversibly sorbed contaminant fraction remains in the soil. This is especially important when considering soil remediation measures and its targets. In multi-stage sorption-desorption batch experiments with TCE, PCE, ortho-xylene and para-xylene and with the sorbents activated carbon, charcoal and a hydrophobic zeolite Y-200, the reversibility of sorption was studied. It could be shown that the structural features of the sorbents are of ample importance for the occurrence of a desorption-resistant fraction. While sorption was mainly reversible for the micro-porous zeolite Y-200 with a rigid pore network, charcoal and the activated carbon showed significant desorption hysteresis. However, following a subsequent sorption step, this fraction eventually desorbs and is re-mobilized.

  8. German-American Workshop on Adult Education with Target Groups = Deutsch-amerikanisches Doppelseminar zur Zielgruppenarbeit.

    ERIC Educational Resources Information Center

    Kerner, Claus, Ed.; Odenbrett, Glenn, Ed.

    This collection includes eight papers (authored by Germans) on adult education programs in Cleveland, Ohio, and eight papers (authored by Americans) about adult education programs in the Federal Republic of Germany as well as German and English introductions to the collection. The following papers are included: "Neue Wege in der…

  9. Zur Hydrogeologie veränderlich fester Gesteine mit Sulfatgestein, Beispiel Gipskeuper (Trias, Grabfeld-Formation)

    NASA Astrophysics Data System (ADS)

    Ufrecht, Wolfgang

    2017-06-01

    In the Southwest German Cuesta, the 150-metre-thick Gipskeuper-Formation (Grabfeld-Formation, Triassic) is dominated by claystones, intercalated with dolostone beds and thin- to massive-bedded sulfate rocks. When in contact with groundwater, the soft claystones experience a reduction of rock strength in several weathering stages. Upon hydration of anhydritic sulfates, the resulting gypsum is also subject to leaching. As both processes are dependent on depth and geomorphological relief, complex aquifer geometries with a high range of hydraulic properties develop. In extreme cases, impermeable, low-permeability and high-permeability zones can be found contiguously within the Gipskeuper. The process of aquifer evolution is described using the example of the Stuttgart basin.

  10. SURFACTANT-ENHANCED EXTRACTION TECHNOLOGY EVALUATION VERSUCHSEININCHTUNG ZUR GRUNDWASSER-UND ALTLASTENSANIERUNG (VEGAS) FACILITY, STUTTGART, GERMANY

    EPA Science Inventory

    This innovative technology evaluation report (ITER) summarized the results of an evaluation of a surfactant-enhanced extraction technology. This evaluation was conducted under a bilateral agreement between the United States (U.S.) Environmental Protection Agency (EPA) Superfund ...

  11. Zur Soziolinguistik in der Bundesrepublik Deutschland (Sociolinguistics in the Federal Republic of Germany)

    ERIC Educational Resources Information Center

    Jachnow, Helmut

    1975-01-01

    Traces the history of sociolinguistic studies in West Germany from the early nineteenth century with Humboldt and reports on the state and purposes of sociolinguistic studies in present-day Federal Republic of Germany. Available from Liber Laeromedel, Box 1205, S-22105 Lund, Sweden (Text is in German.) (TL)

  12. German-American Workshop on Adult Education with Target Groups = Deutsch-amerikanisches Doppelseminar zur Zielgruppenarbeit.

    ERIC Educational Resources Information Center

    Kerner, Claus, Ed.; Odenbrett, Glenn, Ed.

    This collection includes eight papers (authored by Germans) on adult education programs in Cleveland, Ohio, and eight papers (authored by Americans) about adult education programs in the Federal Republic of Germany as well as German and English introductions to the collection. The following papers are included: "Neue Wege in der…

  13. Rear-Guard Actions against an "Impoverishing Delusion": Anmerkungen zur Situation der Auslandsgermanistik in den Americas

    ERIC Educational Resources Information Center

    McCarthy, John A.

    2010-01-01

    This contribution responds to the previous three articles by highlighting common concerns across the Americas. It also offers suggestions for how the field of German might want to move forward in an inclusive fashion. Key principles of orientation are EU language policy and transcultural education as a transformative experience in shaping…

  14. Zur Analyse von Deutsch-Englischen Interferenzerscheinungen (On the Analysis of German-English Interference Phenomena).

    ERIC Educational Resources Information Center

    Cornell, Alan; Schmidt, Helmut

    1980-01-01

    Presents examples of interference phenomena, lexical, grammatical, and orthographic, which occurred in the translation section of examinations given to prospective teachers of English in German university-preparatory high schools. The elements of error are analyzed, and corrected versions are supplied. (IFS/WGA)

  15. Zur Arbeit mit Bildern im Englischunterricht (Work with Pictures in English Teaching)

    ERIC Educational Resources Information Center

    Stein, Oswald

    1977-01-01

    Discusses the use of drawings in foreign language courses for adults. Accompanying texts should be unambiguous--preferably reports of experiences or anecdotes. Also considered is the use of political cartoons. A list of expressions for use in discussing pictures is included. (Text is in German.) (IFS/WGA)

  16. Integrierte Speichersystem-Architektur zur Unterstützung hochschulübergreifender IT-Dienste

    NASA Astrophysics Data System (ADS)

    Biardzki, Christoph; Baur, Werner; Reiner, Bernd

    Speichersysteme bilden die Basis für zahlreiche höherschichtige IT-Dienste. Auch im IntegraTUM-Projekt der Technischen Universität München werden zahlreiche Dienste wie E-Mail oder E-Learning angeboten, die hochverfügbaren Speicherplatz benötigen. Die Arbeit beschreibt die Umsetzung dieser Speichersysteme sowie auch neu implementierte Dateidienste für Endbenutzer. Es werden die Anforderungen und Rahmenbedingungen diskutiert und die implementierte Lösung vorgestellt.

  17. Zur Arbeit am literarischen Text im Fremdsprachenunterricht (Work on Literary Texts in Teaching Foreign Languages)

    ERIC Educational Resources Information Center

    Riehme, Joachim

    1975-01-01

    Current emphasis on communication in FL teaching should not rule out the use of literary texts, for these reveal segments of human life and patterns of language. The treatment of such texts is discussed. (Text is in German.) (IFS/WGA)

  18. Zur Arbeit mit Bildern im Englischunterricht (Work with Pictures in English Teaching)

    ERIC Educational Resources Information Center

    Stein, Oswald

    1977-01-01

    Discusses the use of drawings in foreign language courses for adults. Accompanying texts should be unambiguous--preferably reports of experiences or anecdotes. Also considered is the use of political cartoons. A list of expressions for use in discussing pictures is included. (Text is in German.) (IFS/WGA)

  19. Europäisches Bewusstsein: Zur Definition Eines Vielschichtigen Begriffes und Seiner Bildungstheoretischen Bedeutung

    NASA Astrophysics Data System (ADS)

    Jobst, Solvejg

    2005-11-01

    EUROPEAN CONSCIOUSNESS: TOWARDS DEFINING A COMPLEX CONCEPT AND ITS EDUCATIONAL SIGNIFICANCE - The present study aims at a definition of `European consciousness'. In particular, it draws on Henri Tajfel's theory of social identity as well as Roland Wakenhut's and Jutta Gallenmüller's moral determination of national consciousness. European consciousness is then defined as a sense of belonging which, depending on certain identification structures and social perspectives, can take such distinct forms of moral consciousness as `Eurocentrism', `European patriotism', or `reflective European consciousness'. Making reference to Wolfgang Klafki's notion of general education, it is finally argued that the emancipatory contribution of schooling to greater European integration consists in mediating precisely this last way of thinking.

  20. Zur Didaktik der medizinischen Fachsprache (On Teaching the Technical Language of Medicine)

    ERIC Educational Resources Information Center

    Becker, Norbert

    1974-01-01

    This guide is designed for teaching Spanish-speaking students of medicine who are learning to read highly specialized texts in their field. A sample text, of seven lines, is presented, followed by a carefully worked out teaching plan, exercises, and a test. (Text is in German.) (IFS/WGA)

  1. Zur Besetzung der Leerstellen von Valenztragern (The Occupation of the Empty Spaces of Valence Bearers)

    ERIC Educational Resources Information Center

    Sommerfeldt, Karl-Ernst

    1973-01-01

    Study of the linguistic means related to the occupation and non-occupation of Leerstellen'' (empty spaces) initiated by semantic and syntactic valence, as in the elliptical usage: Die Henne legt wieder. (Eier)'' (The hen is laying again. YeggsI). (RS)

  2. Lifelong Learning: One Focus, Different Systems. Studien zur Erwachsenenbildung, Band 19.

    ERIC Educational Resources Information Center

    Harney, Klaus, Ed.; Heikkinen, Anja, Ed.; Rahn, Sylvia, Ed.; Schemmann, Michael, Ed.

    These 17 articles on different subjects of the broader theme "lifelong learning" represent the latest results of the discussions of the Vocational Education and Culture Research Network. An introduction (Klaus Harney et al.) provides summaries of the contents. The articles are "The Global and International Discourse of Lifelong…

  3. Konzept zur Übertragung von Daten in verteilten Echtzeitsystemen via Ethernet

    NASA Astrophysics Data System (ADS)

    Pirkl, Werner

    Immer höher werdende Datenraten und größer werdende Verteilung von Echtzeitsystemen lässt bestehende, parallele Bussysteme als Übertragungsmedium zwischen Rechnern schnell Grenzen erreichen. In einem Prototyp wird deshalb versucht, Echtzeitdaten mit Hilfe eines Kommunikationsmodells über Ethernet zu verteilen.

  4. Zur Besetzung der Leerstellen von Valenztragern (The Occupation of the Empty Spaces of Valence Bearers)

    ERIC Educational Resources Information Center

    Sommerfeldt, Karl-Ernst

    1973-01-01

    Study of the linguistic means related to the occupation and non-occupation of Leerstellen'' (empty spaces) initiated by semantic and syntactic valence, as in the elliptical usage: Die Henne legt wieder. (Eier)'' (The hen is laying again. YeggsI). (RS)

  5. Von den Flitterwochen zur distanzierten Partnerschaft - Deutsche Manager in internationalen M&A

    NASA Astrophysics Data System (ADS)

    Fuchs, Martina; Schalljo, Martin

    2017-02-01

    Cross-border mergers and acquisitions (M&A) require considerable intercultural openness on the part of the managers involved. A recent wave of takeovers by private equity investors and foreign investors from emerging economies has challenged German executives. In cases of friendly takeovers, as described in this study, managers at first appear to extend a cosmopolitan welcome to the new owners. However, further analysis of structural hermeneutics reveals latent normative professional ethics of managers which lead to practices of distancing, in particular from young investors from China, India, and Russia.

  6. BOOK REVIEW: Einsteins Kosmos. Untersuchungen zur Geschichte der Kosmologie Relativitatstheorie und zu Einsteins Wirken und Nachwirken

    NASA Astrophysics Data System (ADS)

    Sterken, C.; Duerbeck, H. W.; Dick, W. R.

    2006-12-01

    This book collects about 15 papers (most of them by one single author) on Einstein and the history of general relativity (GR) and the foundations of relativistic cosmology. The matter not only deals with Einstein and his times, but also with pre-GR ideas, and with the interplay of Einstein and his colleagues (opposing as well as supporting personalities). As the title indicates, all papers are written in German, but they include comprehensive Abstracts both in German and English. The book is illustrated with quite a number classical - but also some far more original though not less beautiful - photographs and facsimiles of documents. The book is edited very well, though the style of references is not quite homogeneous. There is no Index. K. Hentschel covers Einstein's argumentation for the existence of graviational redshift, and the initial search for empirical support. The error analysis of observational evidence supporting relativistic light deflection is discussed in a paper by P. Brosche. In particular, H. Duerbeck and P. Flin - in their description of the life and work of Silberstein, who was quite sceptic on the significance of the observational verifications a la Eddington - include the transcription of two most revealing letters by Silberstein to Sommerfeld (1919) and to Einstein (1934). In the first letter, Silberstein clearly shows his scientific maturity and integrity by scrutinising the observational evidence supporting light deflection, presented at a joint meeting of the Royal Society and the Royal Astronomical Society. The second letter, which is more a personal letter, includes lots of political references and connotations. Some of Einstein's political views are also revealed by D.B. Herrmann on the basis of his own correspondence with E.G. Straus, a collaborator of Einstein's. In a consequent paper, S. Grundmann gives remarks on Herrmann's contribution and illustrates Einstein's attitude towards Marx, Engels, Lenin and Stalin. M. Schemmel discusses Schwarzschild's cosmological speculations, and wonders why some people do immediately grasp the meaning and consequence of newly proposed doctrines, whereas the bulk of the contemporaneous scientists respond in a rather low profile. T. Jung reviews Einstein's contribution to cosmology, leading to the Friedmann-Einstein and Einstein-de Sitter universes (with a detailed Appendix on the Friedmann-Lemaitre cosmology), and also presents the cosmological work of Selety, and his correspondence with Einstein. In a subsequent paper, H.-J. Schmidt comments on Einstein's criticism on de Sitter's solution of the Einstein field equations. Controversies with Einstein are elaborated by G. Singer (on Friedmann) and by K. Roessler (on Lemaitre). J. Renn and T. Sauer discuss Mandl's role in the publication history of Einstein's papers, notably Einstein's short paper on gravitational lensing. Finally, the book concludes with a contribution by D.B. Herrmann about the relationship between Einstein and Archenhold Observatory (where Einstein gave his first Berlin popular lecture in 1915), the transcription of H.-J. Treder's 1979 public address at the Einstein memorial plaque, and an inventory list of about 50 Einstein memorabilia - monuments, busts, plaques - compiled by W.R. Dick. This book is based on ideas approached in a historical context from the individual perspective of the authors. It is a real treasure trove of information and basic references on the history of GR, and it also covers quite some grounds with mathematical equations.

  7. Zur Verwendung von Lehrmedien im englischen Anfangsunterricht (On the Use of Teaching Aids in Beginning English)

    ERIC Educational Resources Information Center

    Pfetsch, Helga

    1975-01-01

    Describes functions and possibility of initiating use of visual and audiovisual aids, including wall pictures, magnetic and flannelboard pictures, film strips, slides and films. Presents exercises and exercise types in connection with the individual media, using English examples. (Text is in German.) (IFS/WGA)

  8. Trawler Icing: A Compilation of Work Done at N.R.C. (Givrage des Chalutiers: Compilation des Recherches Effectuees au C.N.R.).

    DTIC Science & Technology

    1980-12-01

    Canadian east coast. This report consolidates various reports and papers written during the course of this project which has now been terminated. A...water spray system to improve the spray distribution over the test panels, the spray concentration was highly variable from run to run. Since these...predominant track. This is illustrated in Figure 16 which is reproduced from Archibald’s paper . The dots with concentric circles around them indicate the

  9. Historical and Conceptual Foundations: As Published in "Distances et Savoirs (D&S-7/2009. A la croisee des recherches, pages 537 to 550)

    ERIC Educational Resources Information Center

    Black, Linda

    2012-01-01

    This article summarizes Section I, "Historical and Conceptual Foundations," of the 2007 "Handbook of Distance Education" (Moore 2007a). Of the eight chapters, two are dedicated to historical perspectives of distance education. Another is centered on research. Five other chapters are focused on distance education theory/theorists. [This article…

  10. Historical and Conceptual Foundations: As Published in "Distances et Savoirs (D&S-7/2009. A la croisee des recherches, pages 537 to 550)

    ERIC Educational Resources Information Center

    Black, Linda

    2012-01-01

    This article summarizes Section I, "Historical and Conceptual Foundations," of the 2007 "Handbook of Distance Education" (Moore 2007a). Of the eight chapters, two are dedicated to historical perspectives of distance education. Another is centered on research. Five other chapters are focused on distance education theory/theorists. [This article…

  11. Survival at Sea for Mariners, Aviators and Search and Rescue Personnel (Survie en mer pour les marins, les aviateurs et le personnel de recherche et de sauvetage)

    DTIC Science & Technology

    2008-02-01

    Studies Conducted in Europe and North America 1939 – 1945 9C-2 Physiological Studies Conducted in Europe and North America 1945 – 1970 9C-3 Practical...discuss problems with distinguished working scientists such as Hervey, Keatinge, McCance, and Pugh. These were the people who changed our whole mind set...lowest recorded survived deep body temperature in an accident victim is 13.7°C [8]. Survival predictions were made from experimental data and case

  12. Model Study of a Proposed Engineering Acoustic Research Facility (Etude sur Modele d’un Projet d’Installation de Recherches en Genie Acoustique)

    DTIC Science & Technology

    1976-07-01

    Toronto E.H. Dudgeon, Head/Chef D.C. MacPhail ,Engine Laboratory/ Laboratoire des moteurs Director/Directeur GO O/L/ D~~~~~~r1ISTRIBUT1I...acceptable et une faible sensibilit A la deviation du jet ont W ddfinies, mais ces dispositifs n’ont &6 rgalisds qu’au detriment du rendement

  13. Recherche empirique sur l'effet de la musique dans l'enseignement suggestopedique du francais (Empirical Research on the Effect of Music in Suggestopedic French Instruction).

    ERIC Educational Resources Information Center

    Schiffler, Ludger

    1986-01-01

    A study of the effectiveness of music techniques in French second-language instruction using the suggestopedic approach is reported. The study attempts to control for variations commonly found in experimental conditions. (MSE)

  14. Policies, Administration, and Management: As published in "Distances et Savoirs" (D & S--7/2009. A La Croisee des Recherches, pages 627 to 641)

    ERIC Educational Resources Information Center

    Thompson, Melody M.; Vidal, Martine

    2011-01-01

    The chapters in Part IV of "Handbook of Distance Education" (2007), "Policies, Administration, and Management," focus on the ways in which policies encourage or hamper the integration of distance education into mainstream educational institutions. The authors provide insights and perspectives into the key policies, roles, structures, processes,…

  15. Actes des journees de linguistique: Colloque sur la recherche etudiante (Proceedings of the Linguistics Conference: Colloquium on Student Research) (Quebec, Canada, March 18-19, 1988).

    ERIC Educational Resources Information Center

    Lepage, Danielle, Ed.; Dominik, Annette, Ed.

    Presentations by students at a colloquium on student research on the occasion of the 50th anniversary of the University of Laval's Faculty of Letters, March 18-19, 1988, include: "Une enquete sur la qualite du francais ecrit au Quebec"; "Amenagement linguistique et neologie"; "Analyse syntaxique des 'arrets et retours' en…

  16. Adaptation of a Turbine Test Facility to High-Temperature Research (Adaptation d’un banc de Turbine aux Recherches pour les Hautes Temperatures,

    DTIC Science & Technology

    1980-12-19

    Des hautes temperatures devant turbine sur turborgacteur et turbines A gaz. (High turbine inlet temperatures in turbo - jet engines and gas turbines ... turbo - jet engines .) Revue Gn(rale de Thermique, No. 166, October 1975 15 D. Arnal Etude exprimentale et thgorique de la transition de la couche J.C...r AD-AIOl 374 ROYAL AIRCRAFT ESTABLISHMENT FARNBOROUBH (ENGLAND) F/B 10/1 ADAPTATION OF A TURBINE TEST FACILITY TO HIGH-TEMPERATURE RESEA--ETC(U) DEC

  17. Policies, Administration, and Management: As published in "Distances et Savoirs" (D & S--7/2009. A La Croisee des Recherches, pages 627 to 641)

    ERIC Educational Resources Information Center

    Thompson, Melody M.; Vidal, Martine

    2011-01-01

    The chapters in Part IV of "Handbook of Distance Education" (2007), "Policies, Administration, and Management," focus on the ways in which policies encourage or hamper the integration of distance education into mainstream educational institutions. The authors provide insights and perspectives into the key policies, roles, structures, processes,…

  18. Patch test reactions to mite antigens: a GERDA multicentre study. Groupe d'Etudes et de Recherches en Dermato-Allergie.

    PubMed

    Castelain, M; Birnbaum, J; Castelain, P Y; Ducombs, G; Grosshans, E; Jelen, G; Lacroix, M; Meynadier, J; Mougeolle, J M; Lachapelle, J M

    1993-11-01

    We performed patch tests with Dermatophagoides pteronyssinus (Dp) antigens from 2 different sources in 355 non-randomly selected patients with atopic dermatitis (AD) and 398 subjects of a control group. The study demonstrated that contact sensitization to mites occurred in an appreciable % of AD cases (20.8%), using commonly available assay products. The differences recorded between the 2 materials tested were related to the concentration of P1 antigen. Non-atopic patients rarely showed positive reactions to Dp (0.75%), when strict criteria for readings were applied and if 2 readings were performed. Patients with positive patch tests did not necessarily show positive immediate skin tests. It would be useful to carry out tests systematically in atopic patients, even if it is not yet known what modern treatment would be best for the patient. Laboratories still do not provide standardized house dust mite preparations--measuring and codifying their biological activity--for use in patch tests. It is to be hoped that the extension of this type of test will lead to the production of better test materials, in syringes with homogeneous dispersion and concentration.

  19. Projets et Resultats des Recherches sur l'Histoire des Bibliotheques en Pologne (Projects and Results of Research on the History of Libraries in Poland).

    ERIC Educational Resources Information Center

    Kubow, Stefan

    The history of library science in Poland and a number of Polish research projects are reviewed in this paper. It is concluded that a considerable amount of research has been done on the history of libraries in Poland, but that this research is fragmented and separated by its focus on theory or methodology. The methodology of scientific research in…

  20. L'Education a l'Heure de la Crise: A la Recherche de l'Equilibre (Education in a Time of Crisis: The Search for Balance).

    ERIC Educational Resources Information Center

    Mayrand, Georges

    1993-01-01

    Describes contemporary educational thought as polarized between the reductionist views of utilitarianism and the unifying views of holism. Explains cultural evolution in terms of the Taoist principles of yin and yang. Evaluates current trends in education, and raises epistemological problems. Discusses the potential effect of utilitarian and…

  1. State of the Art in Research on Medical Countermeasures Against Biological Agents (Etat de la recherch sur les contre-mesures medicales de lutte contre les agents biologiques)

    DTIC Science & Technology

    2016-08-01

    detection, cell differentiation, chromosome analysis, cell sorting and typing, bacterial counting, hematology, DNA content, and drug discovery. The...Press, Washington, DC, USA, 1583-1591. [24] Domi A and Moss B. (2002). Cloning the vaccinia virus genome as a bacterial artificial chromosome in...Omics” Methods in Vaccine Generation and Production 2-3 2.2.2.1 Bacterial Vaccine Production 2-3 2.2.2.2 Synthetic Biology and Viral Vaccines 2-5

  2. Inventory of Research on Adult Human Resource Development in Canada. Inventaire de la Recherche sur le Developpement des Ressources Humaines Adultes au Canada.

    ERIC Educational Resources Information Center

    Page, Garnet T.; Caldwell, George

    This bilingual directory of research (1963-68) in the development of adult human resources in Canada indicates types of projects undertaken, principal objectives, institutions involved, amounts and sources of funding. It also shows which areas of research have been well covered, those with little or no coverage, and those which might be given a…

  3. Fiches pratiques: Les comparatifs lavent plus blanc; Signe particulier: Belier; Avis de recherche; Mont de piete (Comparatively Speaking; The Sign of Aries; Missing Persons; Pawnshop).

    ERIC Educational Resources Information Center

    Bourdet, Jean-Francois; And Others

    1992-01-01

    Four activities for the French language classroom are described. These include helping students discover comparative expressions by using advertisements; using horoscopes for teaching vocabulary; using a missing persons report as a source for intermediate to advanced level discussion, collective writing, and questions; and a video designed to…

  4. Filières nucléaires et gestion du plutonium et des actinides mineurs la recherche de la flexibilité du cycle

    NASA Astrophysics Data System (ADS)

    Thomas, Jean-Baptiste

    2002-10-01

    Transuranics management concerns all NPP types, because of the specifications for a sustainable development. Multiple recycling is mandatory. Neutronic abundance can be obtained in fast spectrum, or by adding external neutrons or (temporarily) with additional 235U. The LWRs can control the plutonium inventory and significantly reduce the amount of transuranics transferred to the geological repository, thanks to the use of innovative nuclear fuel in a limited part of the NPP fleet. HTR adapted to transuranics burning can help. In the future, in addition to the liquid metal FBR, a strategy based on a gas cooled technological line and advanced fuel opens a second path towards fast spectra. Strategies for defining the optimal mix of reactor types in the nuclear fleet at a given time and demonstrating the fuel cycle flexibility are under study. To cite this article: J.-B. Thomas, C. R. Physique 3 (2002) 783-796.

  5. La politique scientifique comme mise en espace-temps de la recherche= Science Policy as Placed in the Space-Time Relationship of Research.

    ERIC Educational Resources Information Center

    Turmel, Andre

    1986-01-01

    The language used by scientists to discuss their work and the social logic underlying scientific research is examined, and viewed from the perspective and as an extension of the space-time continuum that scientists study. (Author/MSE)

  6. Amniocentesis and mother-to-child human immunodeficiency virus transmission in the Agence Nationale de Recherches sur le SIDA et les Hépatites Virales French Perinatal Cohort.

    PubMed

    Mandelbrot, Laurent; Jasseron, Carine; Ekoukou, Dieudonné; Batallan, Agnès; Bongain, André; Pannier, Emmanuelle; Blanche, Stéphane; Tubiana, Roland; Rouzioux, Christine; Warszawski, Josiane

    2009-02-01

    The objective of the study was to investigate whether performing an amniocentesis increased mother-to-child transmission of human immunodeficiency virus (HIV)-1 (MTCT). We studied HIV -1 infected mothers and their children enrolled in the multicenter French Perinatal HIV Cohort from 1985 to 2006. One hundred sixty-six amniocenteses were performed among 9302 singleton pregnancies, the proportion increasing from 1.0% before 2001 to 4.7% in 2005-2006. Use of highly active antiretroviral therapy (HAART) was more frequent in the amniocentesis group (58.4% vs 33.2%). MTCT tended to be higher in the amniocentesis group, among mothers who received no antiretroviral agents (25.0%; 3/12 vs 16.2%; 343/2113; P = .41) as well as among mothers receiving zidovudine monotherapy or a double-nucleoside reverse transcriptase inhibitor combination (6.1%; 3/49 vs 3.3%; 117/3556; P = .22), but the difference was not significant. Among 81 mothers receiving HAART, there was no case of MTCT. Our results suggest that amniocentesis is not a major risk factor for mother-to-child transmission in mothers treated with effective antiretroviral therapy.

  7. Recherches Sur La Psychologie de L'enfant de Milieu Defavorise. Rapport- synthese. (Research Relating to the Psychology of the Child in Disadvantaged Environments. Summary Report).

    ERIC Educational Resources Information Center

    Caouette, Charles E.; Bourbeau, Gerald

    Thirteen doctoral dissertations and five masters theses are summarized in this report of research on the disadvantaged child. Contained in each individual summary are the detailed descriptions of the experimental task, the results obtained and the analysis of these results. The eighteen individual theses are concerned with topics such as:…

  8. Operations Research / Operations Analysis Orientation Course Curriculum for NATO Nations (Programme d’initiation a la recherche / l’analyse operationnelle pour les pays de l’OTAN)

    DTIC Science & Technology

    2014-09-01

    generation and application of state-of-the- art , validated knowledge for defence and security purposes. S&T activities embrace scientific research...Decision Process”, The Journal of the Faculty of Engineering and Architecture of Gazi University, 2013. ANNEX - 58 STO-TR-SAS-098 ANNEX TO SAS-098...Research Directorate CZ Distribution Information Centre Royal Military Academy – Campus Renaissance Fakinos Base Camp, S.T.G. 1020 Mladoboleslavská

  9. Actes du colloque: Tendances actuelles de la recherche sur la langue parlee (Conference Presentations: Current Trends in Research on Oral Language).

    ERIC Educational Resources Information Center

    Auger, Julie, Ed.

    Student papers presented at a sociolinguistics conference include: "La variation phonologique [d'une voyelle] a Hull"; "La force illocutoire des pronoms personnels 'je' et 'tu' en tant qu'insignes des places d'ou parlent les femmes et les hommes"; "L'emploi des modes indicatif et subjonctif dans le francais parle de la…

  10. Two Worlds of Day Care: The Practitioner and the Researcher = Deux Mondes des Services de Garderie: La Pratique et la Recherche.

    ERIC Educational Resources Information Center

    Pence, Alan R.

    This brief essay, presented in parallel English and French versions, highlights the process by which day care practice and day care research have begun to overlap. First, the development of day care research in North America is presented in a "generational" model. It is argued that a shift has occurred from general child care…

  11. Natural Selection and the Audition Process: Dance Science in Context. Monaco Dance Forum/Association Danse Medecine Recherche Colloquium, Monaco, 1-4 April 2010

    ERIC Educational Resources Information Center

    Sporton, Gregory

    2010-01-01

    The Monaco Dance Forum (MDF), a biennale of dance that takes place in the beautiful and affluent surroundings of Monte Carlo, has chosen this time to celebrate as its theme the centenary of the "Ballets Russes." Diaghilev's famous company made its first tour in 1909, an event that unarguably changed ballet's status as an art form, and heralded…

  12. Les competences spatiales geometriques et l'acculturation mathematique inuite. Rapport de recherche (Geometric Spatial Competencies and Inuit Mathematical Acculturation. Research Report).

    ERIC Educational Resources Information Center

    Pallascio, Richard; Allaire, Richard; Lafortune, Louise; Mongeau, Pierre

    Inuit children and children from an urban environment, inhabiting as they do differing spatial environments, contrasted with one another in terms of perception, representation, and the manifestation of geometric, topographic, and projective properties. The general hypothesis of this research is that the process of mathematical acculturation is…

  13. L'Education a l'Heure de la Crise: A la Recherche de l'Equilibre (Education in a Time of Crisis: The Search for Balance).

    ERIC Educational Resources Information Center

    Mayrand, Georges

    1993-01-01

    Describes contemporary educational thought as polarized between the reductionist views of utilitarianism and the unifying views of holism. Explains cultural evolution in terms of the Taoist principles of yin and yang. Evaluates current trends in education, and raises epistemological problems. Discusses the potential effect of utilitarian and…

  14. Kativik School Board Initiated Research: The Basis for Informed Decision Making = Recherches a l'Initiative de la Commission Scolaire Kativik: Pour des Decisions Eclairees = [Inuttitut Version].

    ERIC Educational Resources Information Center

    Taylor, Donald M.; Wright, Stephen C.

    Presented in Inuttitut, French, and English, this report summarizes research initiated by the Kativik School Board, which oversees education in Nunavik (northern Quebec). Four studies examined the current status of Inuttitut in Nunavik, the intellectual ability of Inuit students, and the effects of bilingual education on Inuit students'…

  15. Les minéraux ferrotitanés du littoral sénégalais: Caractérisation et recherche de leur origine

    NASA Astrophysics Data System (ADS)

    Allouc, J.; Samama, J. C.; Fauvel, P. J.

    1999-04-01

    Iron-titanium rich grains ('ilmenites' to a various degree of weathering) occuring along the coast line of Senegal and deriving from various parent units are characterized from their size, texture, magnetic and geochemical properties. Both the corresponding data and their multivariate analysis lead to the conclusion that the 'ilmenite' grains derive from various sources, mainly local ones, except in the area of Saint-Louis where occur more distal grains from Mauritania. In the North of Cap Vert and in the South of Gambia, the 'Continental Terminal' formation represents the main source of the 'ilmenite' grains. Along the 'Petite Côte', 'ilmenites' derive mainly from the Maastrichtian formations of the 'Massif de Ndiass'. Volcanic formation of the Cap Vert area does not represent a major source, except in the area of the extremity of the peninsula. The old ferricretes do not significantly contribute to the recent accumulation. The 'ilmenites' concentration along the beach lineis controlled by the different sedimentary cycles; the nouakchottian transgression beeing probably the most important event. In the Senegalese basin, a significant amount of the 'ilmenites' originated from the 'Continental Terminal' formation appears to derive from basic metamorphic rocks of the Mauritanide orogen. In the northern part of the basin, 'ilmenite' assemblage contains grains suggesting intermediate to acidic magmatic parental rocks. The calc-alkaline igneous complex from the structural units emplaced in the late Paleozoic on the NW margin of the Mauritanide orogen, and the Reguibat uplift, are two possible sources. The 'ilmenite' association found in the Maastrichtian formation probably derives from various paleozoic formations but its primary origin can not be deciphered.

  16. Natural Selection and the Audition Process: Dance Science in Context. Monaco Dance Forum/Association Danse Medecine Recherche Colloquium, Monaco, 1-4 April 2010

    ERIC Educational Resources Information Center

    Sporton, Gregory

    2010-01-01

    The Monaco Dance Forum (MDF), a biennale of dance that takes place in the beautiful and affluent surroundings of Monte Carlo, has chosen this time to celebrate as its theme the centenary of the "Ballets Russes." Diaghilev's famous company made its first tour in 1909, an event that unarguably changed ballet's status as an art form, and heralded…

  17. Aspects theoretiques et methodologiques de la recherche sur le traitement discursif des representations sociales (Theoretical and Methodological Aspects of Research on the Discourse Analysis of Social Representations).

    ERIC Educational Resources Information Center

    Matthey, Marinette

    2000-01-01

    This article presents some theoretical reflections on the relationship between social representations-as they are conceptualized in sociopsychology--and discourse. An interdisciplinary point of view is advocated that accounts for both linguistics and sociopsychology. Methodological comments are presented and a way to convey theoretical reflections…

  18. The eMouveRecherche application competes with research devices to evaluate energy expenditure, physical activity and still time in free-living conditions.

    PubMed

    Guidoux, Romain; Duclos, Martine; Fleury, Gérard; Lacomme, Philippe; Lamaudière, Nicolas; Saboul, Damien; Ren, Libo; Rousset, Sylvie

    2017-04-08

    The proliferation of smartphones is creating new opportunities to monitor and interact with human subjects in free-living conditions since smartphones are familiar to large segments of the population and facilitate data collection, transmission and analysis. From accelerometry data collected by smartphones, the present work aims to estimate time spent in different activity categories and the energy expenditure in free-living conditions. Our research encompasses the definition of an energy-saving function (Pred(EE)) considering four physical categories of activities (still, light, moderate and vigorous), their duration and metabolic cost (MET). To create an efficient discrimination function, the method consists of classifying accelerometry-transformed signals into categories and of associating each category with corresponding Metabolic Equivalent Tasks. The performance of the Pred(EE) function was compared with two previously published functions (f(η,d)aedes,f(η,d)nrjsi), and with two dedicated sensors (Armband® and Actiheart®) in free-living conditions over a 12-hours monitoring period using 30 volunteers. Compared to the two previous functions, Pred(EE) was the only one able to provide estimations of time spent in each activity category. In relative value, all the activity categories were evaluated similarly to those given by Armband®. Compared to Actiheart®, the function underestimated still activities by 10.1% and overestimated light- and moderate-intensity activities by 7.9% and 4.2%, respectively. The total energy expenditure error produced by Pred(EE) compared to Armband® was lower than those given by the two previous functions (5.7% vs 14.1% and 17.0%). Pred(EE) provides the user with an accurate physical activity feedback which should help self-monitoring in free-living conditions.

  19. Research and Development of Ram/Scramjets and Turboramjets in Russia (La Recherche et le Developpement des Statoreacteurs, des Statoreacteurs a Combustion Supersonique et des Turbostatoreacteurs en Russie)

    DTIC Science & Technology

    1993-12-01

    1) High temperature working region : the air excess coefficient was no more than a = 2 - 3. 2) Most experimental objects: models and full scaled... introduced . The turbulent heat and mass transfer coefficients arc expressed through turbulent viscosity coefficient using Prandtl and Schmidt...efficiency in the whole region the second characteristic is introduced D = JJpu (C -<C>)2dF / fjpu dF/<C>2 , F F which defines the nonuniformity of mass

  20. [The Institut de recherches scientifiques et industrielles Jacquemin (1894-1967), in Malzéville, near Nancy. An almost pharmaceutical industry].

    PubMed

    Jacquemin, Lore; Labrude, Pierre

    2011-02-01

    First devoted to research and its applications in chemistry and microbiology, the institute was created in 1894. Its founder, Georges Jacquemin was the son of the professor of chemistry of the school of pharmacy of Nancy. He was first a student in pharmacy but he did not finish the last examinations... Three years ago, he created or participated to the creation of the Institut La Claire, near Morteau in the Jura, with same activities. The Institut Jacquemin settled in special houses and laboratories where were studied and prepared numerous chemical and biological products, particularly selected yeasts used in wine-making, brewery, cider-making, also phytosanitary chemical products and, in 1902, Ferment Jacquemin which was a depurative and was considered as a drug. Georges Jacquemin died in 1925 but his institute remainded in activity with his coworkers until 1967 and closed totally only in 1976.

  1. Zur Arbeit mit der Zeitung im Deutschunterricht auf fortgeschrittener Stufe: Zur Erweiterung des Wortschatzes (On Working with the Newspaper in Teaching German at the Advanced Level: Toward Increasing the Vocabulary)

    ERIC Educational Resources Information Center

    Bretschneider, Hildegund

    1974-01-01

    Using newspapers in FL teaching gives pupils experience reading original texts, and offers possibilities for vocabulary building. Here one must be aware of vocabulary differences between West and East Germany (FRG, GDR), particularly in ideological areas. The writer shows how vocabulary drills can be based on newspaper material. (Text is in…

  2. Recherche d'une politique de gestion des stocks d'eau de barrages-réservoirs en vue de soutenir les étiages. 2. Utilisation d'un modèle alterné annuel apports-déficits pour la recherche des conditions de gestion

    NASA Astrophysics Data System (ADS)

    Bocquillon, C.; Masson, J. M.

    1983-01-01

    In the upper catchment of the River Loire, France, the construction of five reservoir dams has been planned to sustain the low flows in the Loire valley. The management of these reservoirs, to be built successively, must be approached from partial or complete points of view in order to establish the daily draft decisions at every stage of the project. A hydrological criteria concerning the low flows at a station in the valley (namely the "objective point") is used to judge the results. It is possible to determine the optimal carry-over storage for this criterion with the use of a long series of simulated inflows to reservoirs and annual deficits, when the future conditions are presumed to be known. The statistical analysis of the results helps in the formulation of the objectives for long-term Q1 assuring the carry-over storage for a predetermined risk of failure. This objective for long-term Q1 will not hold good if the low flow is severe. Thus some deterministic and statistical hypotheses have been used to formulate an objective for the mean term of flow Q2 ( tj) which is calculated each day tj and adjusted to the hydrological conditions of the year. The target draft Cb at the objective point is the minimum of the pair [( Q1, Q2 ( tj)]. Water is discharged each day to meet this target flow, while maintaining all the constraints of the flows downstream to the reservoirs. It takes into account the time needed for transfer of water and permits a good prediction of either the flow propagation in the upper watershed or the evolution of the inflows from downstream catchments. A modular model is used to calculate the daily flow. The results obtained from simulation were satisfactory.

  3. 2004 Space Report: Environment and Strategy for Space Research at NATO’s Research and Technology Organisation (RTO) (Compte rendu Espace 2004 : Environnement et strat gie de la recherche spatiale de l’Organisation pour la recherche et la technologie de l’OTAN)

    DTIC Science & Technology

    2007-02-01

    military needs of the Alliance, to maintain a technological lead, and to provide advice to NATO and national decision makers. The RTO performs its...ouverte » conduit à une perspective coût-retour qui limite la participation des chercheurs aux forums RTO. Les barrières organisationnelles à une...system infrastructure, the research performed within the NATO RTO can be used to improve and protect data and services obtained via assured access to

  4. Investitionen aus den BRIC-Staaten - Grund zur Sorge für Unternehmen, Beschäftigte und Kommunen?

    NASA Astrophysics Data System (ADS)

    Franz, Martin; Henn, Sebastian

    2017-02-01

    Investments from BRIC countries - Brazil, Russia, India and China - are playing an increasingly important role in Germany. However, both the public and the potentially affected labour force often adopt sceptical, and sometimes even hostile attitudes towards investors from these countries. This article shows that apart from a few exceptions investors from the BRIC countries are generally better than their reputation precedes. An important conclusion drawn in this paper is that investors should not be received with stereotypes. Rather, it is necessary to perform deeper investigations into their strategies and the specific investment goals in each case. This is all the more necessary to ensure that investments from BRIC countries do not conflict with the domestic firms' interests or of their personnel. In fact, they can assist to increase the competitiveness of German firms, and as such not only prove beneficial for the workforce but also for Germany as a business destination.

  5. Learning, Adjustment and Stress Disorders: With Special Reference to Tsunami Affected Regions. Beitrage zur Padagogischen und Rehabilitationspsychologie. Volume 1

    ERIC Educational Resources Information Center

    Witruk, Evelin, Ed.; Riha, David, Ed.; Teichert, Alexandra, Ed.; Haase, Norman, Ed.; Stueck, Marcus, Ed.

    2010-01-01

    This book contains selected contributions from the international workshop Learning, "Adjustment and Stress Disorders--with special reference to Tsunami affected Regions" organised by Evelin Witruk and the team of Educational and Rehabilitative Psychology at the University of Leipzig in January 2006. The book contains new results and the…

  6. PHREASIM - Ein Expertensystem zur Simulation von Fließverhältnissen in Grundwassermessstellen und deren unmittelbarem Nahfeld

    NASA Astrophysics Data System (ADS)

    Drießen, Joachim; Schöttler, Marc; Enzmann, Frieder; Lakdawala, Zahra; Steiner, Konrad; Popov, Peter; Iliev, Oleg; Drews, Michael; Wieber, Georg; Kersten, Michael

    2015-09-01

    In this study, a new numerical solver based on a coupling of the Navier-Stokes and Brinkman equations is presented. The solver can model 3D horizontal steady-state flow conditions with interactions between the aquifer, gravel-pack, well screen, and open borehole at the interface between the borehole and the surrounding porous filter and aquifer, thus solving the critical transition from porous to free flow. The solver is embedded in the workflow of the PHREASIM expert system. It allows for designing a broad variety of well designs and flow scenarios while considering the permeabilities and geometries of the involved microstructures. Stationary flow scenarios can be visualized in any cross-section and at any discrete point within the model. In order to verify the validity of the numerical approach, a variety of flow scenarios were investigated in sand tank model experiments and simulated with PHREASIM. By comparing the results of both simulations and experimental measurements performed using identical boundary conditions, PHREASIM proved to be viable for accurately replicating virtually steady-state flow conditions. PHREASIM aims to support the interpretation and significance of flow data gained by borehole flow measuring systems like PHREALOG.

  7. The long road to the invention of the telescope (German Title: Der lange Weg zur Erfindung des Fernrohres)

    NASA Astrophysics Data System (ADS)

    Willach, Rolf

    The author traces the road to the invention of the telescope through the centuries. In the beginning, there was the lens in its simplest and most pristine form: ground quartz crystals, which were used primarily for pure decoration use. Samples from antique times to the high middle ages are investigated to find out the technology of their production. On the basis of this knowledge, the different fundamental steps are outlined which led from the ground crystals of liturgical devices as produced in monastic workshops to the invention of spectacles. Subsequently, the evolution of spectacles and the technique of grinding used for their production is traced from the early 14th up to the 17th century, and documented by numerous examples. It is also shown that none of these inventions was made by contemplating in the study, but became possible through numerous practical experiments, accidental insights and intensive interactions with the contemporary cultural and political developments in old Europe.

  8. Contributions to the History of Astronomy, Vol. 8 (German Title: Beiträge zur Astronomiegeschichte, Band 8)

    NASA Astrophysics Data System (ADS)

    Dick, Wolfgang R.; Hamel, Jürgen

    The contributions span a time interval of more than 450 years. There are biographical investigations on Georg Joachim Rheticus, C.W.A. von Wahl and K.F. Heym, investigation on a reprint of a chapter of the principal work of Nicolaus Copernicus, on Christoph Scheiner and the "camera obscura", and, with respect to the history of timekeeping, on the "big Nuremberg clock". 19th century topics are: a contribution on the honorary doctorate of Joseph Fraunhofer, and on the construction of a lunar globe by Wilhelmine Witte, while the report on Friedrich Wilhelm Bessel and the cholera pandemia in Königsberg in the year 1831 gives a view into everyday life of scientists. 20th century topics are: the contributions on Bruno Thüring in Vienna and his relations with national socialism, as well as on Arthur Beer, Albert Einstein and the Warburg library. The book concludes by short communications, obituaries and book reviews.

  9. Learning, Adjustment and Stress Disorders: With Special Reference to Tsunami Affected Regions. Beitrage zur Padagogischen und Rehabilitationspsychologie. Volume 1

    ERIC Educational Resources Information Center

    Witruk, Evelin, Ed.; Riha, David, Ed.; Teichert, Alexandra, Ed.; Haase, Norman, Ed.; Stueck, Marcus, Ed.

    2010-01-01

    This book contains selected contributions from the international workshop Learning, "Adjustment and Stress Disorders--with special reference to Tsunami affected Regions" organised by Evelin Witruk and the team of Educational and Rehabilitative Psychology at the University of Leipzig in January 2006. The book contains new results and the…

  10. Texte zur Entwicklung des verstehenden Hoerens: Now Listen Carefully (Texts for the Development of Aural Comprehension: "Now Listen Carefully")

    ERIC Educational Resources Information Center

    Eitlinger, Ingrid

    1975-01-01

    Discusses the possibility of introducing the booklet "Now Listen Carefully" (Volk und Wissen, Berlin 1975), which contains 72 texts. A topical arrangement of the texts into teaching units is attempted, and hints on method are given. (Text is in German.) (IFS/WGA)

  11. Die physikalischen Umweltwissenschaften und das Militär Zur Erforschung Grönlands im Kalten Krieg

    NASA Astrophysics Data System (ADS)

    Heymann, Matthias

    Die modernen Umweltwissenschaften stehen heute im Mittelpunkt von Forschungsförderung und öffentlicher Aufmerksamkeit. Im Zuge des seit den 1970er Jahren erwachten Interesses am globalen Wandel der Umwelt und den damit verknüpften Problemen, ist ihre Bedeutung rasch gestiegen. Viele Wurzeln der modernen Umweltwissenschaften liegen jedoch im Kalten Krieg.

  12. "Hochleistern über die Schulter geschaut" - Konzeption eines Lehrvideos zur Vermittlung von Problemlösekompetenz

    NASA Astrophysics Data System (ADS)

    Kujath, Bertold; Schwill, Andreas

    Leistungsstarke Problemlöser zeigen ein deutlich anderes Vorgehen beim Bearbeiten von typischen Informatikproblemen als schwächere Problemlöser, das hat eine Vergleichsstudie mit Hoch- und Niedrigleistern ergeben. Auffällig war das Fehlen informatikspezifischer Herangehensweisen bei der Problembearbeitung durch Niedrigleister, obwohl die dazu notwendigen Werkzeuge wie etwa Baumstrukturen oder Rekursion durchaus bekannt waren. Aber auch viele allgemeine Empfehlungen der Problemlöseforschung, wie etwa das Zerlegen eines Problems in Teilprobleme oder das Durchführen einer Problemanalyse vor der eigentlichen Bearbeitung, bleiben bei schwachen Problemlösern unbeachtet. Die Frage, wie nun die deutlich effizienteren Strategien der Hochleister didaktisch aufgearbeitet werden können, um sie an Niedrigleister zu vermitteln, soll im vorliegen Beitrag anhand der Konzeption eines Lehrvideos beantwortet werden.

  13. Contributions to the History of Astronomy, Vol. 7 (German Title: Beiträge zur Astronomiegeschichte, Band 7)

    NASA Astrophysics Data System (ADS)

    Dick, Wolfgang R.; Hamel, Jürgen

    The topics of this volume extend from the work of the islamic scienticst al-Tusi in the 13th century to the development of astronomical instrumentation at the Carl Zeiss Jena Company in the second half of the 20th century. The contents of the remaining articles are found between these limits: the well-known textbooks of Johannes de Sacrobosco, Tycho Brahe's stays in Augsburg, Gottfried Kirch's calendars, published around 1700, a portrait of Bessel, made during his Königsberg time, Fraunhofer's successors at the Munich Optical Institute, and Einstein's cosmological ideas in his ``Four lectures on the Theory of Relativity''. The earliest disputation of the learned Jesuit Christoph Scheiner is printed for the first time in a German translation. The volume is concluded by a bibliographical overview on historical Venus transits, additional short notes, an obituary of Jerzy Dobrzycki, and book reviews. Most papers are written in German. Main papers have English abstracts.

  14. Contributions to the History of Astronomy, Vol. 4. (German Title: Beiträge zur Astronomiegeschichte, Band 4)

    NASA Astrophysics Data System (ADS)

    Dick, Wolfgang R.; Hamel, Jürgen

    This issue contains mostly biographical studies ranging from the outstanding Jesuit astronomer Chr. Scheiner to 18th/19th century scholars to the important astronomical writer B. H. Bürgel. Concerning Scheiner a recently found contemporary obituary is reproduced. Hitherto unknown copy-books of university lectures by Scheiner and by the astrophysicist K. Schwarzschild are being discussed. Biographical contributions deal with P.-F. Tonduti in Avignon, J. G. Doppelmayr in Nuremberg, C. F. Scheithauer in Chemnitz, J. W. H. Lehmann in the Brandenburg area as well as L. Weinek in Leipzig und Prag. An additional list of memorial places for astronomers in Berlin, Potsdam and surroundings, short contributions and book reviews conclude this volume. All papers in German. Main papers with English abstracts.

  15. Contributions to the History of Astronomy, Vol. 10 (German Title: Beiträge zur Astronomiegeschichte, Band 10)

    NASA Astrophysics Data System (ADS)

    Dick, Wolfgang R.; Duerbeck, H. W.; Hamel, Jürgen

    The contributions of this volume deal with the calendaric reckoning of Geminos of Rhodos, the Nuremberg scholar G.P. Harsdörffer in connection with the first astronomical card game and the Christian constellations, J. Harrison and his precision chronometers, astronomical matters in texts by M. Claudius, the relations between F.X. von Zach and J. von Utzschneider, letters of F.W. Bessel, the mechano-optical workshops of A. Dolberg in Rostock, the Leipzig astronomer F. Hayn, the history of the first high school observatory in Chemnitz, and H.P. Robertson's world model. The book concludes by obituaries, short communications, and reviews of books dealing with the history of astronomy.

  16. Ueben-Pruefen. Zur Klaerung zweier zentraler Begriffe (Drilling-Testing. On the Clarifications of Two Central Concepts)

    ERIC Educational Resources Information Center

    Arendt, Manfred

    1976-01-01

    It is shown that drilling tends to become contaminated with elements of testing. The two activities are defined, and suggestions are given for designing drills free of testing. (Text is in German.) (IFS/WGA)

  17. Auswerteverfahren zur Kontrolle der Verfüllqualität in Erdwärmesonden mit faseroptischen Temperaturmessungen

    NASA Astrophysics Data System (ADS)

    Riegger, Mathieu; Heidinger, Philipp; Lorinser, Bruno; Stober, Ingrid

    2012-06-01

    Borehole heat exchangers (BHE) are used for geothermal heating of buildings and infrastructure. To ensure ecologic and economic efficiency, the BHE and the bedrock must be hermetically sealed by grouting material. Incomplete grouting can also be dangerous for groundwater quality and can induce damage. This manuscript describes a new evaluation method for detection of defects in the grouting by continuous fibre optic temperature measurements along the borehole depth while carrying out enhanced geothermal response tests. The described method also works well without groundwater flow within the defects of the BHE grouting.

  18. An der Schwelle zur Zweisprachigkeit: Fremdsprachenunterricht fur Fortgeschrittene (On the Threshold of Bilingualism: Foreign Language Learning for Advanced Students).

    ERIC Educational Resources Information Center

    Kubler, Silvia, Ed.; Portmann, Paul R., Ed.

    1994-01-01

    This collection of articles on Bilingualism includes: "Fremdsprachenunterricht fur Fortgeschrittene: ein Uberblick" (Foreign Language Learning for Advanced Students: An Overview) (Paul R. Portmann); "Never Mind the Width, Feel the Quality: From Quantity to Quality in Language Teaching at Advanced Levels" (Mike Makosch); "Irren ist menschlich: Ein…

  19. Modernisierung durch Feminisierung? Zur Geschichte des Lehrerinnenberufes (Modernization through Feminization -- On the History of the Profession of Women Teachers).

    ERIC Educational Resources Information Center

    Jacobi, Juliane

    1997-01-01

    Argues that the large contribution of women to the history of reform pedagogics substantiates the thesis that the professional image of the teacher is largely determined by the feminization of the profession. Contrasts this approach with other recent theses on the professionalization of male and female teachers. (DSK)

  20. Zur Ökophysiologie, Sexualität und Populationsgenetik litoraler Gammaridea — ein Überblick

    NASA Astrophysics Data System (ADS)

    Bulnheim, H.-P.

    1991-09-01

    Comparative investigations on the physiological capacities in the euryhaline amphipods Gammarus locusta, G. oceanicus, G. salinus, G. zaddachi and G. duebeni were reviewed. In order to assess the adaptations of these species to the abiotic conditions of their environment, the following criteria were examined: oxygen consumption in relation to ambient salinity and temperature levels, respiratory responses following osmotic stress, resistance capacities to oxygen deficiency, resistance to aerial exposure and the simultaneous presence of hydrogen sulphide. Covering the range from marine to typically brackish-water inhabitants, the 5 species show adaptive responses in the above-mentioned order. Respiration is less intensely modified by external factors, and oxygen consumption decreases. Accompanied by faster rates of acclimation to new steady states of performance, resistance capacities increase. The significance of the findings obtained is discussed in relation to the environmental requirements of the amphipods considered. Based on breeding experiments, the sex-determining systems reported thus far in Gammarus species are outlined. As demonstrated in G. duebeni, a more or less pronounced influence of external factors such as photoperiod may become effective. A preponderance of males was noted when offspring were raised under long-day photoperiods, whereas females prevailed under short-day conditions. In terms of the critical daylength, the light per day was estimated as being between 13 and 14 h (Elbe estuary population). Feminizing microporidians ( Octosporea effeminans, Thelohania herediteria), which are transovarially transmitted, can interfere with the system of sex determination and sex differentiation of the host. As reflected in various G. duebeni populations, they cause a maternally transferred sex-ratio condition by the production of all-female broods, thereby mimicking extrachromosomal inheritance. An increase of the salinity level to 25 30‰ results in a disappearance of O. effeminans. In both microsporidians, long exposure to low temperatures (≤4°C) produces eggs which are not all parasitized. Furthermore, intersexuality can be induced by changing environmental factors. Microsporidian species have no influence on sex differentiation in G. duebeni celticus, G. salinus, G. locusta and G. pulex. Patterns of relative electrophoretic mobilities of proteins and the distribution of allele frequencies at polymorphic gene loci can be utilized for species diagnosis and for the evaluation of the relationships between different taxa, particularly at and below the species level. As exemplified by studies on several gammarids from marine, brackish and freshwater environments, inter- and infraspecific gene-enzyme variation is described. Electrophoretic investigations on natural populations of the euryhaline amphipods G. zaddachi, G. salinus, G. tigrinus and others from different geographic areas provided evidence of considerable biochemical genetic variation. In Talitrus saltator- and Talorchestia deshayesii-populations the extent of variability based on micro-and macrogeographic aspects is illustrated. The large-scale genetic divergence is demonstrated by comparison of samples obtained from the Baltic, North, Atlantic and northern Mediterranean Seas.

  1. Zur Sicherheit: frag doch! Forschungsbericht Nr 30 (In Order to be Safe, Just Ask. Research Bulletin No. 30).

    ERIC Educational Resources Information Center

    Flammer, August; And Others

    Eighty-eight college students were invited to cook a chocolate mousse and were allowed first to ask any question that seemed helpful to completing the task. The questions were answered immediately according to a predetermined schema: in one condition the subjects were told that the task would be rather easy, in the other condition they were told…

  2. Contributions to the History of Astronomy, Vol. 9; (German Title: Beiträge zur Astronomiegeschichte, Band 9)

    NASA Astrophysics Data System (ADS)

    Dick, Wolfgang R.; Duerbeck, H. W.; Hamel, Jürgen

    The contributions deal with astronomical events of the past 1000 years. We elucidate the person of the single European observer of the supernova of 1006, and the views of Christoph Scheiner and Otto von Guericke on the structure and substance of the cosmos. A study of the development of the Copernican and the cosmological principles conclude this group of themes. Biographical investigations were carried out on the clockmaker Nikolaus Lilienfeld, the astronomers Johann Wurzelbau, Friedrich Wilhelm Toennies and Boris Karpov as well as the “panbabylonist” Alfred Jeremias. Astronomers can be active also in poetry and fiction. This is shown in the studies of Johann Leonard Rost and Friedrich Wilhelm Bessel. Finally, Johannes Hevelius' Observatory in Danzig/Gdansk, destroyed by a fire in 1679, is reconstructed by means of printed sources, old maps and photographs. The book concludes by short communications, obituaries and book reviews.

  3. Zur Abschätzung von Wärmeleitfähigkeiten der oberflächennahen Lockergesteinsschichtenfolge in Norddeutschland

    NASA Astrophysics Data System (ADS)

    Otto, Roland

    2012-12-01

    In the course of a groundwater investigation program in east Schleswig-Holstein, groundwater temperature measurements were performed in groundwater observation wells. First, the heat flux density of the investigation area was determined. The heat flow ranged from 20 to 77 mW m-2. Near the boundaries of the area, subsurface salt structures cause an increase in heat flow to the earth's surface. In the centre of this region the heat flow is due to convective processes, and is somewhat low. Here the groundwater recharge as well as the influx from top to bottom affects the temperature field. By means of heat flux densities and the measured temperature gradients, the thermal conductivity was estimated. For clays in the study area the thermal conductivity averaged 1.4 W m-1 K-1 ranging between 1.1 and 1.7 W m-1 K-1. For the coarse grained sand the conductivity was 3.0 W m-1 K-1 and for the fine sands it was 2.8 W m-1 K-1. Due to its heterogeneity, the thermal conductivity of the till ranged between 1.6 and 2.8 W m-1 K-1, depending on the mineralogical composition, the bulk density and the water content of the till. The average thermal conductivity was 2.1 W m-1 K-1.

  4. Contributions to the History of Astronomy, Vol. 3. (German Title: Beiträge zur Astronomiegeschichte, Band 3)

    NASA Astrophysics Data System (ADS)

    Dick, Wolfgang R.; Hamel, Jürgen

    The main papers of this issue deal with previously unknown details of the foundation of the astronomical observatories in Gotha and in Königsberg (with numerous original documents by F.W. Bessel), with the Mecklenburg ordnance survey (1853-1873, with previously unknown letters by C.F. Gauss), with the merits of the Leipzig astronomer G.A. Jahn, with the internationality of the Astronomische Gesellschaft, and with early, previously little noted works on the expansion of the Universe. The issue contains a description of the important collection of sundials in the Kassel museum, discussions about the Medieval ``Phantom Period'', about Goethe's description of the zodiacal light, as well as obituaries and book reviews. Most papers in German, one in English.

  5. Kopplung eines auf der Momentenmethode basierenden Computerprogramms mit einem FEM-Algorithmus zur Berechnung von elektromagnetischen Streuproblemen im medizinischen Bereich

    NASA Astrophysics Data System (ADS)

    Schick, M.; Landstorfer, F. M.

    2004-05-01

    Am Beispiel der Verkopplung von medizinischen Geräten über den menschlichen Körper werden elektromagnetische Störphänomene im Klinikbereich betrachtet. Für die Berechnung dieser komplexen Szenarien wird zum einen die Momentenmethode (MoM) verwendet, die sich in besonderem Maße für die Berücksichtigung metallischer Strukturen und offener Streuprobleme eignet, und zum anderen die Methode der Finiten Elemente (FEM), mit der die Eigenschaften des menschlichen Körpers besser berücksichtigt werden können. Mit Hilfe des Äquivalenzprinzips lässt sich das Gesamtproblem in zwei Teile zerlegen, in ein inneres und in ein äußeres. Der Außenraum wird dabei mit der MoM behandelt und das Innere, d.h. der Körper mit der FEM. Die Kopplung der beiden Methoden erfolgt an der Körperoberfläche über äquivalente Oberflächenströme. Durch Lösen des resultierenden linearen Gleichungssystems für das gesamte Problem lassen sich dann die Oberflächenströme und die über die Kontinuitätsgleichung miteinander verknüpften elektromagnetischen Felder bestimmen.

  6. Contributions to the History of Astronomy, Vol. 11. (German Title: Beiträge zur Astronomiegeschichte, Band 11)

    NASA Astrophysics Data System (ADS)

    Dick, Wolfgang R.; Duerbeck, H. W.; Hamel, Jürgen

    2011-08-01

    The contributions deal with astronomical concepts, historical observatories and biographical studies. Newly found copies of Copernicus' principal work are described, the development of the concepts "sphaera" and "orbis coelestis" from ancient times via Copernicus to Kepler is investigated. The concept of harmonical cosmology of Kepler and A. Kircher is analyzed in a major paper. A rediscovered letter by Kepler is interpreted. Other papers deal with the university observatory of Bützow (Mecklenburg-Western Pomerania), the observatories installed in Strasbourg in the 17th and early 19th centuries, and the Jesuit observatory which existed in Graz (Styria) in the 18th century, as well as the unrealized plans for an observing station of Vienna University Observatory in the 1940s. Einstein's thoughts about Friedmann's cosmological papers are presented. Biographical sketches on Philipp Feselius (1565-1610), Ferdinand Adolph Freiherr von Ende (1760-1816), Wilhelm Ebert (1871-1916) and Karl Julius Lohnert (1885-1944) are supplemented by an analysis of the social background of the important Astronomers of the 20th century. The claim that Jupiter's moons were described already 105 years before Galilei is contradicted in a discussion. The book concludes by short communications, obituaries and book reviews.

  7. Kartei unveroffentlichter linguistischer Arbeiten zur Deutschen Spra che der Gegenwart (KULA) (Bibliography of Unpublished Linguistic W orks on Contemporary German)

    ERIC Educational Resources Information Center

    Toman, Jindrich

    1974-01-01

    This bibliography includes titles of unpublished works in various fields of linguistics such as grammar (morphology, phonology and syntax), socioli nguistics, psycholinguistics, foreign language instruction, language acquisit ion, discourse analysis, poetics, etc. (Text is in German.) (DS)

  8. New insights into the biography of Gottfried Kirch. (German Title: Neue Erkenntnisse zur Biographie von Gottfried Kirch)

    NASA Astrophysics Data System (ADS)

    Herbst, Klaus-Dieter

    New biographical results of Gottfried Kirch, the most outstanding astronomer around 1700 in German lands, are outlined on the basis of newly found sources and the first-time inclusion of additional letters from his correspondence, which comprises 600 letters. Special attention is drwawn to his stay in Langgrün and Lobenstein in the Vogtland, in Leipzig, Coburg, Guben and Berlin. In addition, new details about his family are revealed, especially about the older children Gottlieb, Heilmann and Theodora, the offspring from his first marriage. A third section deals with the possibilities which are to be expected from a systematic evaluation of Kirch's correspondence. Only about 100 out of 600 letters have been used for historical publications until now.

  9. Anwendung einer Switched-System Modellierung zur Stabilitätsanalyse von zeitkontinuierlichen singlebit ΣΔ-Wandlern

    NASA Astrophysics Data System (ADS)

    Stegemann, S.; Zorn, C.; Brückner, T.; Ortmanns, M.; Mathis, W.

    2011-08-01

    Im Hinblick auf die Optimierung von zeitkontinuierlichen ΣΔ-Wandlern ist ein genaues Verständnis der dynamischen Eigenschaften des Systems von essentieller Bedeutung. In dieser Arbeit wird der ΣΔ-Modulator dafür in die Klasse der Mixed-Signal Systeme eingeordnet und als Übertragungssystem mit geschalteter Rückkopplung betrachtet. Mit diesem Switched-System-Modell können unter Zuhilfenahme einer geeigneten Zustandsraumdarstellung die Signalamplituden der internen Integratoren sowie die Maximalamplitude am Quantisierereingang bestimmt werden. Unter Verwendung einer Worst-Case Analyse ist es damit möglich, Aussagen über den Aussteuerbereich der Integratoren sowie der maximal stabilen Eingangsamplitude zu treffen. Die Vorgehensweise wird anhand eines Beispielmodulators dargestellt.

  10. Uberlegungen zur Arbeit mit Strukturubungen nach dem "Tandemprinzip" (Reflections of Work with Structured Exercises Based on the "Tandem Principle")

    ERIC Educational Resources Information Center

    Leupold, Eynar

    1972-01-01

    The tandem principle grows from the belief that foreign languages can be mutually supportive and informative if taught together. The pairing of French and German students for pattern practice in each other's native language is a practical application of the principle. (RS)

  11. Investitionen aus den BRIC-Staaten. Grund zur Sorge für Unternehmen, Beschäftigte und Kommunen?

    NASA Astrophysics Data System (ADS)

    Franz, Martin; Henn, Sebastian

    2017-04-01

    Investments from BRIC countries - Brazil, Russia, India and China - are playing an increasingly important role in Germany. However, both the public and the potentially affected labour force often adopt sceptical, and sometimes even hostile attitudes towards investors from these countries. This article shows that apart from a few exceptions investors from the BRIC countries are generally better than their reputation precedes. An important conclusion drawn in this paper is that investors should not be received with stereotypes. Rather, it is necessary to perform deeper investigations into their strategies and the specific investment goals in each case. This is all the more necessary to ensure that investments from BRIC countries do not conflict with the domestic firms' interests or of their personnel. In fact, they can assist to increase the competitiveness of German firms, and as such not only prove beneficial for the workforce but also for Germany as a business destination.

  12. Contributions to the History of Astronomy, Vol. 5 (German Title: Beiträge zur Astronomiegeschichte, Band 5)

    NASA Astrophysics Data System (ADS)

    Dick, Wolfgang R.; Hamel, Jürgen

    This book contains articles on 16th century horoscopes, on Athanasius Kircher's ``Organum Mathematicum'', on Gottfried Kirch's idea of an astronomical society, on a stellar photometer dating from 1786, on Bessel's review of Gauss' ``Theoria Motus'', on letters by F.X. von Zach, on the discovery of the minor planet Eros, as well as on the astronomers Christoph Scheiner, Johann Philipp von Wurzelbau, Georg Koch and Felix Linke. Short contributions and book reviews conclude this volume. Most papers are written in German. Main papers have English abstracts.

  13. Empirische Untersuchung zur Effektivitaet von Schulfunksendungen im Englischunterricht (Empirical Investigations of the Effectiveness of School Radio Broadcasting in Teaching English)

    ERIC Educational Resources Information Center

    Waas, Ludwig

    1977-01-01

    Reports on an experiment in school radio broadcasting, in 7th and 8th grade classes in a Munich school. Subsequent tests showed that the use of school broadcasting produced better results in the target area (learning and using polite formulas) than conventional instruction. (Text is in German.) (IFS/WGA)

  14. Contributions to the History of Astronomy, Vol. 1. (German Title: Beiträge zur Astronomiegeschichte, Band 1)

    NASA Astrophysics Data System (ADS)

    Dick, Wolfgang R.; Hamel, Jürgen

    This volume of the ``Contributions to the History of Astronomy'' presents new papers on Apian, Copernicus, Rheticus, Kepler, Newton, Lichtenberg, Mädler, Beer, Hansen, as well as on the history of the Königsberg Observatory and the Astrophysical Observatory Bothkamp.

  15. Ueben-Pruefen. Zur Klaerung zweier zentraler Begriffe (Drilling-Testing. On the Clarifications of Two Central Concepts)

    ERIC Educational Resources Information Center

    Arendt, Manfred

    1976-01-01

    It is shown that drilling tends to become contaminated with elements of testing. The two activities are defined, and suggestions are given for designing drills free of testing. (Text is in German.) (IFS/WGA)

  16. Zur landeskundlichen Ausrichtung von Hoerverstaendnisuebungen im Sprachlabor (On Directing Language Lab Hearing-Understanding Exercises toward Understanding of the Country)

    ERIC Educational Resources Information Center

    Schumann, Adelheid

    1974-01-01

    Presents an aural comprehension exercise (French) for the language laboratory, which has been undergoing try-out at the Romance Language Seminar of the University of Berlin since the summer semester of 1973. Basic to the concept of this exercise is the combining of oral training and area study. (Text is in German.) (IFS/WGA)

  17. Empirische Untersuchung zur Effektivitaet von Schulfunksendungen im Englischunterricht (Empirical Investigations of the Effectiveness of School Radio Broadcasting in Teaching English)

    ERIC Educational Resources Information Center

    Waas, Ludwig

    1977-01-01

    Reports on an experiment in school radio broadcasting, in 7th and 8th grade classes in a Munich school. Subsequent tests showed that the use of school broadcasting produced better results in the target area (learning and using polite formulas) than conventional instruction. (Text is in German.) (IFS/WGA)

  18. Inégalités scolaires à Cotonou (Bénin) : rôle croissant de l'encadrement familial à la recherche d'une éducation de qualité

    NASA Astrophysics Data System (ADS)

    Gastineau, Bénédicte; Kpadonou, Norbert; Delaunay, Valérie; Assogba, Eve Senan; Gnélé, Josette

    2015-08-01

    Educational inequality in Cotonou (Benin): the increasing role of family supervision in obtaining quality education - In Cotonou, the economic capital of Benin, primary school enrolment is available to all. Girls and boys go to school. Very few children between the ages of 6 and 14 years have never attended school. However, not all children have the same educational experience. Drawing on data from a socio-economic survey conducted in 2012, the authors examine pupils' schooling conditions. Their analyses confirm the hypotheses derived from the literature review: inequalities have moved from outside school to inside it. Generalised access to primary school has not done away with inequalities - far from it - and today in Cotonou the schooling and learning conditions are very diverse. The most advantaged children are enrolled in private schools, have a tutor and are helped with their homework by their parents. These children are those who come from the more affluent social classes and in particular those whose parents have the highest level of formal education. The inequalities once observed in access to school have now shifted to extracurricular supervision and the choice of school. The survey also highlighted that the few children still entirely outside of the school system are foster children.

  19. Outcomes in adult critically Ill cancer patients with and without neutropenia: a systematic review and meta-analysis of the Groupe de Recherche en Réanimation Respiratoire du patient d'Onco-Hématologie (GRRR-OH)

    PubMed Central

    Bourmaud, Aurélie; Azoulay, Elie; Mokart, Djamel; Darmon, Michael

    2017-01-01

    PURPOSE Whether neutropenia has an impact on the mortality of critically ill cancer patients remains controversial, yet it is widely used as an admission criterion and prognostic factor. METHODS Systematic review and meta-analysis. Studies on adult cancer patients and intensive care units were searched on PubMed and Cochrane databases (2005-2015). Summary estimates of mortality risk differences were calculated using the random-effects model. RESULTS Among the 1,528 citations identified, 38 studies reporting on 6,054 patients (2,097 neutropenic patients) were included. Median mortality across the studies was 54% [45–64], with unadjusted mortality in neutropenic and non-neutropenic critically ill patients of 60% [53–74] and 47% [41–68], respectively. Overall, neutropenia was associated with a 10% increased mortality risk (6%-14%; I2 = 50%). The admission period was not associated with how neutropenia affected mortality. Mortality significantly dropped throughout the study decade [−11% (−13.5 to −8.4)]. This mortality drop was observed in non-neutropenic patients [−12.1% (−15.2 to −9.0)] but not in neutropenic patients [−3.8% (−8.1 to +5.6)]. Sensitivity analyses disclosed no differences in underlying malignancy, mechanical ventilation use, or Granulocyte-colony stimulating factor use. Seven studies allowed the adjustment of severity results (1,350 patients). Although pooled risk difference estimates were similar to non-adjusted results, there was no significant impact of neutropenia on mortality (risk difference of mortality, 9%; 95% CI, −15 to +33) CONCLUSION Although the unadjusted mortality of neutropenic patients was 11% higher, this effect disappeared when adjusted for severity. Therefore, when cancer patients become critically ill, neutropenia cannot be considered as a decision-making criterion. PMID:27661125

  20. Acute kidney injury in critically ill patients with haematological malignancies: results of a multicentre cohort study from the Groupe de Recherche en Réanimation Respiratoire en Onco-Hématologie

    PubMed Central

    Darmon, Michael; Vincent, François; Canet, Emmanuel; Mokart, Djamel; Pène, Frédéric; Kouatchet, Achille; Mayaux, Julien; Nyunga, Martine; Bruneel, Fabrice; Rabbat, Antoine; Lebert, Christine; Perez, Pierre; Renault, Anne; Meert, Anne-Pascale; Benoit, Dominique; Hamidfar, Rebecca; Jourdain, Mercé; Schlemmer, Benoit; Chevret, Sylvie; Lemiale, Virginie; Azoulay, Elie

    2015-01-01

    Background Cancer patients are at high risk for acute kidney injury (AKI), which is associated with high morbidity and mortality. We sought to appraise the incidence, risk factors, and outcome of AKI in a large multicentre cohort study of critically ill patients with haematological malignancies. Methods We used a retrospective analysis of a prospectively collected database. The study was carried out in 17 university or university-affiliated centres in France and Belgium between 2010 and 2012. AKI was defined according to the Acute Kidney Injury Network (AKIN) definition. Results Of the 1011 patients admitted into the intensive care unit (ICU) during the study period, 1009 were included in this study. According to the AKIN definition, 671 patients (66.5%) developed an AKI during their ICU stay, of which 258 patients (38.4%) were AKI stage 1, 75 patients (11.2%) AKI stage 2 and 338 patients (50.4%) AKI stage 3. After adjustment for confounders, main adverse risk factors of AKI were older age, severity [non-renal Sequential Organ Failure Assessment (SOFA)], history of hypertension, tumour lysis syndrome, exposure to nephrotoxic agents and myeloma. Hospital mortality was 44.3% in patients with AKI and 25.4% in patients without AKI (P < 0.0001). After adjustment for confounders, AKI was independently associated with hospital mortality [OR 1.65 (95% CI 1.19–2.29)]. Overall, 271 patients required renal replacement therapy (RRT), of whom 57.2% died during their hospital stay as compared with 31.2% (P < 0.0001) in those not requiring RRT. Conclusion Two-thirds of critically ill patients with haematological malignancies developed AKI. Hospital mortality in this population of patients developing AKI or requiring RRT is close to that in general ICU population. PMID:26597921

  1. Virtual Reality: State of Military Research and Applications in Member Countries (La realite virutelle: L’etat actuel des travaux de recherche et des applications militaires dans les pays membres de l’Alliance)

    DTIC Science & Technology

    2003-02-01

    This tool uses mathematics to produce a 3D body representation. It allows one to manipulate posture and movement of the manikin. The user of this type...requirements for military VR applications in the domains of training, robotics, remote operations and command and control . On the second day, we examined...cockpit standing in front of 3 screens as shown in Figure 7A.7. The simulation is run on a Silicon Graphic’s computer from a control room. Figure 7A.7

  2. A Research Agenda for Scientific and Technical Information Held in Lisbon, Portugal on 7-9 April 1992 (Un Programme de Recherche pour l’Information Scientifique et Technique).

    DTIC Science & Technology

    1992-11-01

    field of inquiry. Good solid research advances fault library science and information science for not ask- the state of the art by contributing to the...further research and application. Ennis (1967) problems faced each day by practitioners. Robert Smith commented that library science research is...under ogy, and technical communications. Library science the title "On Information Science." Keren raises interest- and information science have been

  3. Gros plan sur les recherches en linguistique, terminologie et didactique. Actes des journees de linguistique (Close-Up of Research on Linguistics, Terminology and Instruction. Proceedings of the Linguistics Conference) (Quebec, Canada, March 2-3, 1989).

    ERIC Educational Resources Information Center

    Bissonnette, Ronald; Ouellet, Micheline

    The following are English translations of the titles of student research papers from a university conference on linguistics: "The Onomastic Syntagm in Geology: A Comparative Study of English and French"; "Hunting Ideology Through Discourse Analysis"; "Peculiarities of Canadian French (Archaisms and Pronunciation): An…

  4. Day Care in the Community. Action Research in Family and Early Childhood. UNESCO Education Sector Monograph = Accueil des jeunes enfants dans la communaute. Recherche-action sur la famille et la petite enfance. UNESCO Secteur de l'education monographie.

    ERIC Educational Resources Information Center

    Allen, John

    Noting demographic pressures and increased poverty most countries experience, this report shows how parents and family members can work in their communities in developing countries to provide low-cost and efficient child care facilities for very young children and explains how such community-based early childhood programs benefit whole families.…

  5. The Role of Information and Research in Educational Decision-Making: Some Questions. Le Role De L'Information Et De La Recherche Dans La Prise De Decisions En Matiere D'Education: Quelques Questions.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France).

    This paper, one of a series of Unesco technical information reports, looks at the educational decision makers in developing nations and examines their access to and use of information and research results. Written in English and in French, the paper consists of five parts. Part one discusses problems encountered by educational policy-makers and…

  6. Extrahepatic manifestations associated with hepatitis C virus infection. A prospective multicenter study of 321 patients. The GERMIVIC. Groupe d'Etude et de Recherche en Medecine Interne et Maladies Infectieuses sur le Virus de l'Hepatite C.

    PubMed

    Cacoub, P; Renou, C; Rosenthal, E; Cohen, P; Loury, I; Loustaud-Ratti, V; Yamamoto, A M; Camproux, A C; Hausfater, P; Musset, L; Veyssier, P; Raguin, G; Piette, J C

    2000-01-01

    From January 1996 to January 1997, 321 patients with an average age of 46 +/- 16 years and chronically infected with hepatitis C virus (HCV) were prospectively enrolled in a study designed to determine the prevalence of extrahepatic manifestations associated with HCV infection in a large cohort of HCV patients, to identify associations between clinical and biologic manifestations, and to compare the results obtained in human immunodeficiency virus (HIV)-positive versus HIV-negative subsets. In a cross-sectional study, clinical extrahepatic manifestations, viral coinfections with HIV and/or hepatitis B virus, connective tissue diseases, and a wide panel of autoantibodies were assessed. Thirty-eight percent (122/321) of patients presented at least 1 clinical extrahepatic manifestation including arthralgia (60/321, 19%), skin manifestations (55/321, 17%), xerostomia (40/321, 12%), xerophthalmia (32/321, 10%), and sensory neuropathy (28/321, 9%). Main biologic abnormalities were mixed cryoglobulins (110/196, 56%), thrombocytopenia (50/291, 17%), and the presence of the following autoantibodies: antinuclear (123/302, 41%), rheumatoid factor (107/280, 38%), anticardiolipin (79/298, 27%), antithyroglobulin (36/287, 13%) and antismooth muscle cell (27/288, 9%). At least 1 autoantibody was present in 210/302 (70%) of sera. By multivariate logistic regression analysis, 4 parameters were significantly associated with cryoglobulin positivity: systemic vasculitis (p = 0.01, odds ratio OR[ = 17.3), HIV positivity (p = 0.0006, OR = 10.2), rheumatoid factor positivity (p = 0.01, OR = 2.8), and sicca syndrome (p = 0.03, OR = 0.27). A definite connective tissue disease was noted in 44 patients (14%), mainly symptomatic mixed cryoglobulinemia and systemic vasculitis, HIV coinfection (23%) was associated with 3 parameters: anticardiolipin (p = 0.003, OR = 4.18), thrombocytopenia (p = 0.01, OR = 3.56), and arthralgia or myalgia (p = 0.017, OR = 0.23). HIV-positive patients presented more severe histologic lesions (p = 0.0004). Extrahepatic clinical manifestations in HCV patients involve primarily the skin and joints. The most frequent immunologic abnormalities include mixed cryoglobulins, rheumatoid factor, antinuclear, anticardiolipin, and antithyroglobulin antibodies. Cryoglobulin positivity is associated with systemic vasculitis and rheumatoid factor and HIV positivity. HIV coinfection is associated with arthralgia or myalgia, anticardiolipin antibodies, and thrombocytopenia.

  7. Systèmes de référence spatio-temporels. Colloque André Danjon "L'astronomie, la recherche et le temps présent".

    NASA Astrophysics Data System (ADS)

    Capitaine, N.; Débarbat, S.

    Contents: 1. Séance commémorative. 2. Méchanique céleste, informatique et relativité. 3. L'astrolabe de Danjon et ses développements. 4. Echelles de temps et astrométrie. 5. Techniques performantes en astrométrie moderne. 6. Des techniques spatiales aux systèmes de reference. 7. Radioastronomie et astronomie.

  8. Analyse factorielle discriminante appliquée à la description des familles de discontinuités et à la recherche des directions préférentielles : cas du site de Chantène

    NASA Astrophysics Data System (ADS)

    Pineau, Annye

    1998-06-01

    Granitic rock masses contain fracture systems that consist of a number of fracture sets. Within a fracture set, variability in orientation is defined by strike and dip. Orientation data have been studied by discriminant analysis for the accurate determination of the fracture set. This method yields a function for classifying multivariate observations into groups. Particular discontinuities named 'individuals' are assigned to a population, based on the proximity relations between individual and most likely clusters initially defined. For each cluster recognized, the preferential direction is determined by means of elementary matrix calculation. The preferred orientations are finally connected to the major features of brittle tectonics.

  9. Financial Implications of the Downs Report on Canadian Academic and Research Libraries. (Repercussions Financieres du Rapport Downs sur les Bibliotheques d'Universite et de Recherche au Canada); The Downs Report in Perspective; (Le Rapport Downs).

    ERIC Educational Resources Information Center

    Blackburn, Robert H.; Stuart-Stubbs, Basil

    A report entitled "Resources of Canadian Academic and Research Libraries," by Robert B. Downs, (ED 019 095) was the subject of conference held in Montreal, in April 1968, sponsored by the Association of Universities and Colleges of Canada and the Canadian Association of College and University Libraries. This document consists of two key…

  10. Biosimilars: from technical to pharmacoeconomic considerations. 30th Rencontres Nationales de Pharmacologie et Recherche clinique pour l'Innovation et l'Evaluation des Technologies de Santé. Tables rondes.

    PubMed

    Girault, Danièle; Trouvin, Jean-Hugues; Blachier-Poisson, Corinne; Gary, François; Laloye, Didier; Bergmann, Jean-François; Casadevall, Nicole; Delval, Cécile; De Sahb Berkovitch, Rima; Fagon, Jean-Yves; Gersberg, Marta; Lassale, Catherine; Lechat, Philippe; Le Jeunne, Claire; Montastruc, Jean-Louis; Prugnaud, Jean-Louis; Ratignier-Carbonneil, Christelle; Rey-Coquais, Cécile

    2015-01-01

    A biosimilar is a biological medicinal product claimed to be similar to a reference biological medicinal product. Its development plan includes studies comparing it with the reference product in order to confirm its similarity in terms of quality, preclinical safety, clinical efficacy, and clinical safety, including immunogenicity. Biosimilars differ from generics both in their molecular complexity and in the specific requirements that apply to them. Since patents on many biological medicinal products will expire within the next 5 years in major therapeutic areas such as oncology, rheumatology and gastroenterology and as those products are so costly to the French national health insurance system, the availability of biosimilars would have a considerable economic impact. The round table has issued a number of recommendations intended to ensure that the upcoming arrival of biosimilars on the market is a success, in which prescribing physicians would have a central role in informing and reassuring patients, an efficient monitoring of the patients treated with biologicals would be set up and time to market for biosimilars would be speeded up.

  11. Outcomes of critically ill patients with hematologic malignancies: prospective multicenter data from France and Belgium--a groupe de recherche respiratoire en réanimation onco-hématologique study.

    PubMed

    Azoulay, Elie; Mokart, Djamel; Pène, Frédéric; Lambert, Jérôme; Kouatchet, Achille; Mayaux, Julien; Vincent, François; Nyunga, Martine; Bruneel, Fabrice; Laisne, Louise-Marie; Rabbat, Antoine; Lebert, Christine; Perez, Pierre; Chaize, Marine; Renault, Anne; Meert, Anne-Pascale; Benoit, Dominique; Hamidfar, Rebecca; Jourdain, Mercé; Darmon, Michael; Schlemmer, Benoit; Chevret, Sylvie; Lemiale, Virginie

    2013-08-01

    PURPOSE Patients with hematologic malignancies are increasingly admitted to the intensive care unit (ICU) when life-threatening events occur. We sought to report outcomes and prognostic factors in these patients. PATIENTS AND METHODS Ours was a prospective, multicenter cohort study of critically ill patients with hematologic malignancies. Health-related quality of life (HRQOL) and disease status were collected after 3 to 6 months. Results Of the 1,011 patients, 38.2% had newly diagnosed malignancies, 23.1% were in remission, and 24.9% had received hematopoietic stem-cell transplantations (HSCT, including 145 allogeneic). ICU admission was mostly required for acute respiratory failure (62.5%) and/or shock (42.3%). On day1, 733 patients (72.5%) received life-supporting interventions. Hospital, day-90, and 1-year survival rates were 60.7%, 52.5%, and 43.3%, respectively. By multivariate analysis, cancer remission and time to ICU admission less than 24 hours were associated with better hospital survival. Poor performance status, Charlson comorbidity index, allogeneic HSCT, organ dysfunction score, cardiac arrest, acute respiratory failure, malignant organ infiltration, and invasive aspergillosis were associated with higher hospital mortality. Mechanical ventilation (47.9% of patients), vasoactive drugs (51.2%), and dialysis (25.9%) were associated with mortality rates of 60.5%, 57.5%, and 59.2%, respectively. On day 90, 80% of survivors had no HRQOL alterations (physical and mental health similar to that of the overall cancer population). After 6 months, 80% of survivors had no change in treatment intensity compared with similar patients not admitted to the ICU, and 80% were in remission. CONCLUSION Critically ill patients with hematologic malignancies have good survival, disease control, and post-ICU HRQOL. Earlier ICU admission is associated with better survival.

  12. A Kalman Filter Integrated Navigation Design for the IAR Twin Otter Atmospheric Research Aircraft (Methode de Navigation Integree a Filtre de Kalman Destinee au Twin Otter de L’Ira Charge des Recherches Atmospheriques)

    DTIC Science & Technology

    1991-04-01

    at specified points in time using a user-supplied description of the desired profile. The resulting trajectory profile dataset is then used as the...PROFST have the following characteristics: 19 IngtFile: A dataset with the generic name PROGW DATAn (where n is a dataset number to denote the...defined in the input dataset PROD DATAn and interpolates between the points using cubic spline techniques. Two output files are normally created from a

  13. Switch to Rilpivirine/Emtricitabine/Tenofovir Single-Tablet Regimen of Human Immunodeficiency Virus-1 RNA-Suppressed Patients, Agence Nationale de Recherches sur le SIDA et les Hépatites Virales CO3 Aquitaine Cohort, 2012–2014

    PubMed Central

    Cazanave, Charles; Reigadas, Sandrine; Mazubert, Cyril; Bellecave, Pantxika; Hessamfar, Mojgan; Le Marec, Fabien; Lazaro, Estibaliz; Peytavin, Gilles; Bruyand, Mathias; Fleury, Hervé; Dabis, François; Neau, Didier

    2015-01-01

    Background. The purpose of this study was to assess the efficacy and tolerability of combined antiretroviral therapy (cART) in human immunodeficiency virus (HIV)-1 virologically suppressed patients who switched to rilpivirine (RPV)/tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC) as a single-tablet regimen (STR). Methods. A retrospective multicenter cohort study was performed between September 2012 and February 2014 in Bordeaux University Hospital-affiliated clinics. Patients with a plasma HIV viral load (VL) lower than 50 copies/mL and switching to STR were evaluated at baseline, 3, 6, 9, and 12 months from switch time (M3, M6, M9, M12) for VL and other biological parameters. Change from baseline in CD4 cell counts was evaluated at M6 and M12. Virological failure (VF) was defined as 2 consecutive VL >50 copies/mL. Results. Three hundred four patients were included in the analysis. Single-tablet regimen switch was proposed to 116 patients with adverse events, mostly efavirenz (EFV)-based (n = 59), and to 224 patients for cART simplification. Thirty of 196 patients with available genotype resistance test results displayed virus with ≥1 drug resistance mutation on reverse-transcriptase gene. After 12 months of follow-up, 93.4% (95.5% confidence interval, 89.9–96.2) of patients remained virologically suppressed. There was no significant change in CD4 cell count. During the study period, 5 patients experienced VF, one of them harboring RPV resistance mutation. Clinical cART tolerability improved in 79 patients overall (29.9%) at M6, especially neurological symptoms related to EFV. Fasting serum lipid profiles improved, but a significant estimated glomerular function rate decrease (−11 mL/min/1.73 m2; P < 10−4) was observed. Conclusions. Overall, virologic suppression was maintained in patients after switching to RPV/TDF/ FTC. This STR strategy was associated with improved tolerability. PMID:26034768

  14. The International Development Research Centre: A Guide for the Canadian University Research Community = Le Centre de recherches pour le developpement international: guide a l'intention des scientifiques des universites Canadiennes.

    ERIC Educational Resources Information Center

    Tillman, George; Wasilewski, Ania, Ed.

    Written in both English and French this is a manual for the Canadian research community. It describes the International Development Research Centre (IDRC) and its operations. The main objective of the IDRC is to assist scientists in developing countries to identify and conduct research into long term practical solutions to development problems.…

  15. Initiation and beyond: molecular determinants of gene regulation. Mechanisms of Transcription Control, A Jacques Monod Conference, sponsored by the Centre National de la Recherche Scientifique, Roscoff, France, September 30-October 4, 1991.

    PubMed

    Umek, R M

    1992-03-01

    The study of the mechanisms of transcriptional control continues to be an exciting area of research. The characterization of the constituents of the initiation complex and their interactions are leading to a greater understanding of gene regulation. The findings presented at this meeting emphasized the need to understand these interactions in three-dimensional space to effectively account for the observed regulation of the initiation of transcription.

  16. Pour un contenu linguistique en oral au 2e cycle du primaire (Toward a Linguistic Oral Content in the Second Cycle of Primary School). Serie: Le Francais a l'ecole primaire. Recherches et essais, numero 11.

    ERIC Educational Resources Information Center

    Ostiguy, Luc; Gagne, Gilles

    It is proposed that linguistic oral content, or metalinguistics, be included in the curriculum of primary school francophone children. This content is not included in the functionally oriented official curriculum. The linguistic content proposed consists of a number of formal variants corresponding to non-formal stylistic markers and respecting…

  17. Fertility in Advanced Societies: A Review of Research: La fécondité dans les sociétés avancées: un examen des recherches.

    PubMed

    Balbo, Nicoletta; Billari, Francesco C; Mills, Melinda

    2013-02-01

    This paper provides a review of fertility research in advanced societies, societies in which birth control is the default option. The central aim is to provide a comprehensive review that summarizes how contemporary research has explained ongoing and expected fertility changes across time and space (i.e., cross- and within-country heterogeneity). A secondary aim is to provide an analytical synthesis of the core determinants of fertility, grouping them within the analytical level in which they operate. Determinants are positioned at the individual and/or couple level (micro-level), social relationships and social networks (meso-level); and, by cultural and institutional settings (macro-level). The focus is both on the quantum and on the tempo of fertility, with a particular focus on the postponement of childbearing. The review incorporates both theoretical and empirical contributions, with attention placed on empirically tested research and whether results support or falsify existing theoretical expectations. Attention is also devoted to causality and endogeneity issues. The paper concludes with an outline of the current challenges and opportunities for future research.

  18. Studying Hostile, Deceptive, and Dangerous Surroundings: Report of a Workshop on Social Research Methods for Non-Permissive Environments (Etudier des Milieux Hostiles, Trompeurs et Dangereux - Rapport Concernant un Atelier sur les Methodes de Recherche Sociale an Milieu non Permissif)

    DTIC Science & Technology

    2010-08-01

    peuvent aider à fournir un cadre plus complet pour ces microcosmes, et identifient également des individus et des entreprises avec des implications... financing , and other security threats. Information is gathered through mandated regulatory reporting from banks and financial institutions. When...for anti-terrorism than the money laundering model of the Global Finance Forum (GFF) because the money laundering model is focused on the money

  19. Employment Survey of 1985 Graduates of Ontario Universities. Summary Report. Research Brief = Enquete sur la Situation Professionnelle des Diplomes de 1985 des Universites de l'Ontario. Rapport Sommaire. Recherche en Bref.

    ERIC Educational Resources Information Center

    Denton, Margaret A.; And Others

    Results of a survey of 1985 graduates from Ontario, Canada, universities are presented in English and French. A total of 36,315 questionnaires were mailed, and the response rate was 56.9%. Information was collected on demographic and background characteristics of the graduates, degree level, major, type of program, decisions for further education,…

  20. Formulation d'un modele mathematique par des techniques d'estimation de parametres a partir de donnees de vol pour l'helicoptere Bell 427 et l'avion F/A-18 servant a la recherches en aeroservoelasticite

    NASA Astrophysics Data System (ADS)

    Nadeau-Beaulieu, Michel

    In this thesis, three mathematical models are built from flight test data for different aircraft design applications: a ground dynamics model for the Bell 427 helicopter, a prediction model for the rotor and engine parameters for the same helicopter type and a simulation model for the aeroelastic deflections of the F/A-18. In the ground dynamics application, the model structure is derived from physics where the normal force between the helicopter and the ground is modelled as a vertical spring and the frictional force is modelled with static and dynamic friction coefficients. The ground dynamics model coefficients are optimized to ensure that the model matches the landing data within the FAA (Federal Aviation Administration) tolerance bands for a level D flight simulator. In the rotor and engine application, rotors torques (main and tail), the engine torque and main rotor speed are estimated using a state-space model. The model inputs are nonlinear terms derived from the pilot control inputs and the helicopter states. The model parameters are identified using the subspace method and are further optimised with the Levenberg-Marquardt minimisation algorithm. The model built with the subspace method provides an excellent estimate of the outputs within the FAA tolerance bands. The F/A-18 aeroelastic state-space model is built from flight test. The research concerning this model is divided in two parts. Firstly, the deflection of a given structural surface on the aircraft following a differential ailerons control input is represented by a Multiple Inputs Single Outputs linear model whose inputs are the ailerons positions and the structural surfaces deflections. Secondly, a single state-space model is used to represent the deflection of the aircraft wings and trailing edge flaps following any control input. In this case the model is made non-linear by multiplying model inputs into higher order terms and using these terms as the inputs of the state-space equations. In both cases, the identification method is the subspace method. Most fit coefficients between the estimated and the measured signals are above 73% and most correlation coefficient are higher than 90%.

  1. L'approache ethnographique comme Methodologie de recherche dans l'examen du processus de construction identitaire (The Ethnographic Approach as Research Methodology in the Investigation of the Process of Identity Construction).

    ERIC Educational Resources Information Center

    Gerin-Lajoie, Diane

    2002-01-01

    Demonstrates how qualitative research, specifically ethnograhy, constitutes an effective means of investigating identity construction, particularly as identity is manifested through language practices. This approach illuminates the complexity of the interaction between language practices and identity. (Author/VWL)

  2. Highlighting the Impacts of North-South Research Collaboration among Canadian and Southern Higher Education Partners (Principaux impacts des collaborations de recherche Nord-Sud entre les partenaires des etablissements d'enseignement superieur du Canada et du Sud)

    ERIC Educational Resources Information Center

    Association of Universities and Colleges of Canada, 2006

    2006-01-01

    The Association of Universities and Colleges of Canada (AUCC) felt it was timely to create an academic forum in which university researchers have the opportunity to engage with their peers and relevant stakeholders and document the impacts of their North-South research collaboration in a peer-reviewed publication. The Association achieved this by…

  3. Highlighting the Impacts of North-South Research Collaboration among Canadian and Southern Higher Education Partners (Principaux impacts des collaborations de recherche Nord-Sud entre les partenaires des etablissements d'enseignement superieur du Canada et du Sud)

    ERIC Educational Resources Information Center

    Association of Universities and Colleges of Canada, 2006

    2006-01-01

    The Association of Universities and Colleges of Canada (AUCC) felt it was timely to create an academic forum in which university researchers have the opportunity to engage with their peers and relevant stakeholders and document the impacts of their North-South research collaboration in a peer-reviewed publication. The Association achieved this by…

  4. Serum lactate levels in infants exposed peripartum to antiretroviral agents to prevent mother-to-child transmission of HIV: Agence Nationale de Recherches Sur le SIDA et les Hépatites Virales 1209 study, Abidjan, Ivory Coast

    PubMed Central

    Ekouevi, Didier Koumavi; Touré, Ramata; Becquet, Renaud; Viho, Ida; Sakarovitch, Charlotte; Rouet, François; Towne-Gold, Besigin; Fassinou, Patricia; Leroy, Valériane; Blanche, Stéphane; Dabis, François

    2006-01-01

    Background Mitochondrial toxicity was described in infants exposed to long-term antiretroviral regimens (ARVs) containing nucleoside analogues for the prevention of mother-to-child transmission of HIV (PMTCT). We measured the serum lactate levels in children born to HIV-1 infected (HIV+) African women receiving short-term ARV PMTCT regimens. Methods A prospective study was conducted in women-child pairs from the third trimester of pregnancy to three months of life. The exposed group was formed by children exposed in utero to nucleoside analogue ARVs, zidovudine (ZDV) or ZDV + lamivudine (3TC) from 32–36 weeks of amenorrhea until delivery. All these women received nevirapine single-dose (NVPsd) at the beginning of labor. The children received ZDV during the first 7 days of life and a NVPsd at day 3. The control group was formed by infants born to HIV+ women who had received NVPsd only and not exposed to nucleoside analogue ARVs. Serum lactate levels were measured at 4, 6 and 12 weeks of life by Cobas Integra 400™. Results A total of 836 blood samples from 338 infants were collected (262 exposed and 76 controls). Median lactacidemia was 1.8 mmol/l, Interquartile Range [1.2–2.7 mmol/l]). Overall serum lactate levels ≥2.5 mmol/l, defining hyperlactatemia were observed in 39 of the 292 infants who had at least two serum lactate measurements, 13.4%, 95% confidence Interval [9.6–17.8%]. The three-month period prevalence of hyperlactatemia did not differ between the exposed group (13.1%) and the control group (14.3%) (p=0.84). All serum lactate levels returned to normal values in all subsequent samples No case of symptomatic hyperlactatemia was detected during the study period. Conclusion Increased lactate levels were identified equally in infants whose mother received a short-term of nucleoside analogues or NVPsd for PMTCT. Although not rare, hyperlactatemia was not related to short-term exposure to nucleoside analogue ARVs PMID:16950945

  5. Liver-related deaths in HIV-infected patients between 1995 and 2010 in France: the Mortavic 2010 study in collaboration with the Agence Nationale de Recherche sur le SIDA (ANRS) EN 20 Mortalité 2010 survey.

    PubMed

    Rosenthal, E; Roussillon, C; Salmon-Céron, D; Georget, A; Hénard, S; Huleux, T; Gueit, I; Mortier, E; Costagliola, D; Morlat, P; Chêne, G; Cacoub, P

    2015-04-01

    The aim of this study was to describe the proportion of liver-related diseases (LRDs) as a cause of death in HIV-infected patients in France and to compare the results with data from our five previous surveys. In 2010, 24 clinical wards prospectively recorded all deaths occurring in around 26 000 HIV-infected patients who were regularly followed up. Results were compared with those of previous cross-sectional surveys conducted since 1995 using the same design. Among 230 reported deaths, 46 (20%) were related to AIDS and 30 (13%) to chronic liver diseases. Eighty per cent of patients who died from LRDs had chronic hepatitis C, 16.7% of them being coinfected with hepatitis B virus (HBV). Among patients who died from an LRD, excessive alcohol consumption was reported in 41%. At death, 80% of patients had undetectable HIV viral load and the median CD4 cell count was 349 cells/μL. The proportion of deaths and the mortality rate attributable to LRDs significantly increased between 1995 and 2005 from 1.5% to 16.7% and from 1.2‰ to 2.0‰, respectively, whereas they tended to decrease in 2010 to 13% and 1.1‰, respectively. Among liver-related causes of death, the proportion represented by hepatocellular carcinoma (HCC) dramatically increased from 5% in 1995 to 40% in 2010 (p = 0.019). The proportion of LRDs among causes of death in HIV-infected patients seems recently to have reached a plateau after a rapid increase during the decade 1995-2005. LRDs remain a leading cause of death in this population, mainly as a result of hepatitis C virus (HCV) coinfection, HCC representing almost half of liver-related causes of death. © 2014 British HIV Association.

  6. Polylactic acid vs. polyacrylamide hydrogel for treatment of facial lipoatrophy: a randomized controlled trial [Agence Nationale de Recherches sur le SIDA et les Hépatites Virales (ANRS) 132 SMILE].

    PubMed

    Lafaurie, M; Dolivo, M; Girard, P-M; May, T; Bouchaud, O; Carbonnel, E; Madelaine, I; Loze, B; Porcher, R; Molina, J-M

    2013-08-01

    The aim of the study was to demonstrate the noninferiority of polyacrylamide hydrogel (PH) vs. polylactic acid (PLA) for the treatment of facial lipoatrophy in HIV-infected adults. A randomized, blinded, multicentre, noninferiority 96-week study was carried out. Patients with facial lipoatrophy were randomly assigned to receive intradermal injections with PH or PLA, and were blinded to the filler. The primary efficacy endpoint was patient satisfaction at week 48 assessed using a visual analogue scale score (VAS). Secondary efficacy end-points included cheek thickness and skin-fold, lipoatrophy grading and quality of life. Safety was assessed by the reporting of adverse events. A total of 148 patients were included in the study; 93% were men, the median age was 47 years, the median CD4 count was 528 cells/μL, and the median duration of antiretroviral therapy was 12 years. Mean VAS increased from 2.8 at baseline to 7.1 and 7.5 in the PLA and PH arms, respectively, at week 48 (P=0.0002 for noninferiority) and was sustained at week 96 (6.7 and 7.9 in the PLA and PH arms, respectively; P=0.003 for noninferiority). Cheek thickness and skin-fold increases and lipoatrophy improvement were similar in the two arms. Quality of life remained unchanged or improved depending on the questionnaire used. In injected patients, subcutaneous nodules emerged in 28 (41%) and 26 (37%) patients in the PLA and PH arms, respectively (P=0.73). Four patients in the PH arm developed severe inflammatory nodules, a median of 17 months after the last injection. PH and PLA have similar efficacies in the treatment of facial lipoatrophy, but PH may be associated with more delayed inflammatory nodules. © 2013 British HIV Association.

  7. Oral calcium tolerance test in the early diagnosis of primary hyperparathyroidism and multiple endocrine neoplasia type 1 in patients with the Zollinger-Ellison syndrome. Groupe de Recherche et d'Etude du Syndrome de Zollinger-Ellison.

    PubMed Central

    Cadiot, G; Houillier, P; Allouch, A; Paillard, M; Mignon, M

    1996-01-01

    BACKGROUND: In patients with the Zollinger-Ellison syndrome, the exclusion of multiple endocrine neoplasia type 1 is of important clinical relevance. Its diagnosis often relies on the existence of primary hyperparathyroidism. AIM AND METHODS: To investigate the parathyroid function of patients with the Zollinger-Ellison syndrome by use of an oral calcium tolerance test to identify both hypercalcaemic and normocalcaemic primary hyperparathyroidism, and, accordingly, multiple endocrine neoplasia type 1. PATIENTS: Among 51 consecutive patients with the Zollinger-Ellison syndrome referred to us between 1988 and 1994, 28 had not been investigated for parathyroid function and were prospectively studied. RESULTS: The investigation of calcium metabolism was abnormal in nine patients. One displayed characteristic features of humoral hypercalcaemia of malignancy. The diagnosis of primary hyperparathyroidism was biologically established in eight patients (29%) and subsequently confirmed by the presence of hyperplasia of the parathyroid glands in the seven patients who underwent neck exploration. Three patients with primary hyperparathyroidism had fasting hyper-calcaemia but the other five had normal fasting serum total calcium concentration and the diagnosis of primary hyperparathyroidism was established by means of the oral calcium tolerance test. Primary hyperparathyroidism was demonstrated in the five patients in whom the diagnosis of multiple endocrine neoplasia type 1 had been previously established on other criteria than primary hyperparathyroidism. By contrast, in three patients, primary hyperparathyroidism, either hypercalcaemic (one patient) or normocalcaemic (two patients) was the sole criteria for the diagnosis of multiple endocrine neoplasia type 1. These results also suggest that primary hyperparathyroidism is present before or close to the time of Zollinger-Ellison syndrome diagnosis. CONCLUSION: Complete investigation of the parathyroid function with calcium calcium and parathyroid hormone concentrations. PMID:8977343

  8. La gestion sanitaire des élevages de rongeurs utilisés en recherche biomédicale: II. Les facteurs pouvant influencer I'implantation d'un programme de gestion sanitaire.

    PubMed

    1986-02-01

    FACTORS INFLUENCING THE IMPLEMENTATION OF A MONITORING PROGRAM: This article outlines the principal factors that should be taken into account in a quality assurance program for rodents used in biomedical research.

  9. Effect of a 14-day course of foscarnet on cytomegalovirus (CMV) blood markers in a randomized study of human immunodeficiency virus-infected patients with persistent CMV viremia. Agence National de Recherche du SIDA 023 Study Group.

    PubMed

    Salmon-Céron, D; Fillet, A M; Aboulker, J P; Gérard, L; Houhou, N; Carrière, I; Ostinelli, J; Vildé, J L; Brun-Vézinet, F; Leport, C

    1999-04-01

    A randomized open-label phase 2 trial compared the virological and clinical effects on cytomegalovirus (CMV) infection of a 14-day course of intravenous foscarnet (100 mg/[kg x 12 h]) or no treatment in 42 HIV-infected patients with < 100 CD4 cells/mm3 and persistent asymptomatic CMV viremia. All CMV markers (blood culture, pp65 antigenemia, plasma and leukocyte DNA) either became negative or decreased significantly at day 14 in the foscarnet group. CMV blood culture results at day 14 were positive in 14% of those receiving foscarnet versus 60% of control patients (P = .004). However, after the end of treatment, all markers reappeared or the virus load rapidly increased. The probability of CMV disease at 6 months was 43% in both groups. Patients who had or who achieved a negative blood culture at any time had a reduced risk of CMV disease (RR = 2.64; 95% CI = 1.24-5.62; P = .02). This study suggests that sequential courses of intravenous foscarnet might not be a good strategy for preemptive therapy in this population and that in patients with a positive blood marker, treatment able to induce and maintain negative CMV blood cultures could constitute an effective intervention.

  10. Mechanisms of virologic failure in previously untreated HIV-infected patients from a trial of induction-maintenance therapy. Trilège (Agence Nationale de Recherches sur le SIDA 072) Study Team).

    PubMed

    Descamps, D; Flandre, P; Calvez, V; Peytavin, G; Meiffredy, V; Collin, G; Delaugerre, C; Robert-Delmas, S; Bazin, B; Aboulker, J P; Pialoux, G; Raffi, F; Brun-Vézinet, F

    2000-01-12

    In the Trilège trial, following induction with a zidovudine, lamivudine, and indinavir regimen, human immunodeficiency virus (HIV) replication was less suppressed by 2-drug maintenance therapy than by triple-drug therapy. To identify mechanisms of virologic failure in the 3 arms of the Trilège trial. Case-control study conducted from February to October 1998. Three urban hospitals in Paris, France. Fifty-eight case patients with virologic failure (HIV RNA rebound to >500 copies/mL in 2 consecutive samples) randomized to 3 therapy groups: triple drug (zidovudine, lamivudine, and indinavir), 8; zidovudine-lamivudine, 29; and zidovudine-indinavir, 21; the case patients were randomly matched with 58 control patients with sustained viral suppression. At virologic failure (S1 sample) and 6 weeks later (S2 sample), assessment of protease and reverse transcriptase gene mutations, plasma indinavir level, and degree of viral load rebound; pill count during induction and maintenance periods. Only 1 primary resistance mutation, M184V, was detected in S1 plasma samples from 4 of 6 patients in the triple-drug and in all 22 in the zidovudine-lamivudine therapy groups and in S2 plasma samples from 3 of 6 in the triple-drug and 20 of 21 in the zidovudine-lamivudine groups. Of controls, M184V was detected in 11 of 13 S1 plasma samples and in 10 of 11 S2 plasma samples. Indinavir levels were undetectable in all S1 samples but 2 in 7 triple-drug cases tested and in the expected range in 11 of 18 S1 and 5 of 12 S2 zidovudine-indinavir case plasma samples tested. Maintenance adherence rates were lower for cases vs controls for zidovudine (P = .05) and indinavir (P = .05). Low indinavir levels, lower adherence rates for zidovudine (P = .04) and lamivudine (P = .03), and rebound to near-baseline values suggested adherence as cause of early failure for 4 of 8 triple-drug cases. In the zidovudine-lamivudine arm, for which case and control adherence rates did not differ significantly (P = .96), most failures occurred late with low rebound, suggesting suboptimal drug potency. In the zidovudine-indinavir arm, virologic failures may be related to both mechanisms. During the maintenance phase early and late virologic failures appeared to be related more to problems of adherence and antiretroviral treatment potency, respectively, than to selection of resistant mutant viruses.

  11. Serum lactate levels in infants exposed peripartum to antiretroviral agents to prevent mother-to-child transmission of HIV: Agence Nationale de Recherches Sur le SIDA et les Hépatites Virales 1209 study, Abidjan, Ivory Coast.

    PubMed

    Ekouevi, Didier Koumavi; Touré, Ramata; Becquet, Renaud; Viho, Ida; Sakarovitch, Charlotte; Rouet, François; Towne-Gold, Besigin; Fassinou, Patricia; Leroy, Valériane; Blanche, Stéphane; Dabis, François

    2006-10-01

    Mitochondrial toxicity was described in infants exposed to long-term antiretroviral regimens containing nucleoside analogues for the prevention of mother-to-child transmission of HIV. We measured the serum lactate levels in children born to HIV-1 infected African women receiving short-term antiretroviral prevention of mother-to-child transmission of HIV regimens. A prospective study was conducted in women-child pairs from the third trimester of pregnancy to 3 months of life. The exposed group was formed by children exposed in utero to nucleoside analog antiretroviral regimens, zidovudine or zidovudine + lamivudine from 32 to 36 weeks of amenorrhea until delivery. All of these women received nevirapine single dose at the beginning of labor. The children received zidovudine during the first 7 days of life and a nevirapine single dose at day 3. The control group was formed by infants born to HIV-1-infected women who had received nevirapine single dose only and who were not exposed to nucleoside analog antiretroviral regimens. Serum lactate levels were measured at 4, 6, and 12 weeks of life by Cobas Integra 400. A total of 836 blood samples from 338 infants was collected (262 exposed and 76 controls). Median lactacidemia was 1.8 mmol/L (interquartile range: 1.2-2.7 mmol/L). Overall serum lactate levels > or = 2.5 mmol/L, defining hyperlactatemia, were observed in 39 of the 292 infants who had > or = 2 serum lactate measurements. The 3-month period prevalence of hyperlactatemia did not differ between the exposed group and the control group. All of the serum lactate levels returned to normal values in all of the subsequent samples. No case of symptomatic hyperlactatemia was detected during the study period. Increased lactate levels were identified equally in infants whose mother received short-term nucleoside analogs or nevirapine single dose for prevention of mother-to-child transmission of HIV. Although not rare, hyperlactatemia was not related to short-term exposure to nucleoside analog antiretroviral regimens.

  12. Prevalence of and factors associated with hepatic steatosis in patients coinfected with hepatitis C virus and HIV: Agence Nationale pour la Recherche contre le SIDA et les hépatites virales CO3 Aquitaine Cohort.

    PubMed

    Neau, Didier; Winnock, Maria; Castéra, Laurent; Bail, Brigitte Le; Loko, Marc-Arthur; Géraut, Laurent; Dupon, Michel; Ragnaud, Jean-Marie; Lacoste, Denis; Lafon, Marie-Edith; Bioulac-Sage, Paulette; Dabis, François

    2007-06-01

    Hepatic steatosis is a common feature in liver biopsies from patients with chronic hepatitis C and is associated with fibrosis progression. Patients with HIV infection and hepatitis C virus (HCV) coinfection have more rapid progression of liver fibrosis than patients with HCV infection alone. The prevalence and factors associated with hepatic steatosis are not well defined in HCV-HIV-coinfected patients. Steatosis was assessed among 148 HCV-HIV-coinfected patients of the Aquitaine Cohort. Steatosis was graded as follows: none, mild (1%-10% of hepatocytes), moderate (11%-30%), severe (31%-60%), and massive (more than 60%). Epidemiologic, clinical, biologic, and therapeutic data were retrieved from the cohort database to investigate the risk factors. Steatosis was present in 67% of patients (95% confidence interval [CI]: 59% to 74%) and was at least moderate in 30% (95% CI: 23% to 38%). Steatosis was macrovesicular or mixed (macro- and microvesicular) in 40.5% and 52.8% of patients, respectively. Necroinflammatory activity was the only factor independent of steatosis (adjusted odds ratio = 5.3, 95% CI: 1.6 to 17.9). When necroinflammatory activity was removed from the model, HCV genotype 3 and body mass index (BMI) were significantly associated with steatosis. Liver inflammation, HCV genotype 3, and BMI are associated with steatosis, a common finding in HCV-HIV-coinfected patients.

  13. Idiopathic chronic eosinophilic pneumonia. A clinical and follow-up study of 62 cases. The Groupe d'Etudes et de Recherche sur les Maladies "Orphelines" Pulmonaires (GERM"O"P).

    PubMed

    Marchand, E; Reynaud-Gaubert, M; Lauque, D; Durieu, J; Tonnel, A B; Cordier, J F

    1998-09-01

    Idiopathic chronic eosinophilic pneumonia (CEP) is a rare disorder of unknown cause with nonspecific respiratory and systemic symptoms but rather characteristic peripheral alveolar infiltrates on imaging, developing mainly in women and in atopic subjects. The disorder is highly responsive to oral corticosteroid therapy, but relapses are frequent on reducing or stopping treatment. The long-term course of the disease and data regarding outcome, particularly the need for prolonged oral corticosteroid therapy and the development of severe asthma, are somewhat contradictory. A multicentric retrospective study was conducted in an attempt to describe better the initial features and, above all, the later course of CEP in a large homogeneous series of 62 stringently selected patients of whom 46 were followed for more than 1 year. The prevalence of smokers was low (6.5%) and about half of our patients (51.6%) had a previous, and often prolonged, history of asthma. The clinical and roentgenographic features were in keeping with previous studies, but we found that computed tomography could disclose ground glass opacities not detected by X-ray, and that migratory infiltrates before treatment were more frequent (25.5%) than reported previously. The bronchoalveolar lavage cellular count always showed a striking eosinophilic pattern, thus allowing distinction between CEP and cryptogenic organizing pneumonia, both syndromes sharing many common clinical and imaging features. About two-thirds of the patients (68%) showed a ventilatory defect in pulmonary function tests, with about one-half of these presenting with an obstructive pattern, sometimes without previous asthma. Along with the submucosal eosinophilic infiltration noted in 2 patients without ventilatory defect, this is strong evidence to confirm that CEP is not only an alveolointerstitial but also an airway disease. The dramatic response to oral corticosteroid therapy was observed in all treated patients. Although only 1 patient initially treated for less than 6 months did not relapse, longer oral corticosteroid therapy in no way provided protection from further relapses. We thus propose to try to wean oral corticosteroid therapy after 6 months in patients without severe asthma, because recurrences remain responsive to oral steroids. However, prolonged oral corticosteroid therapy was necessary in the majority of patients, with 68.9% of those followed for more than 1 year still on oral corticosteroid therapy at the last follow-up, either because of relapse or because of severe asthma.

  14. Switch to Rilpivirine/Emtricitabine/Tenofovir Single-Tablet Regimen of Human Immunodeficiency Virus-1 RNA-Suppressed Patients, Agence Nationale de Recherches sur le SIDA et les Hépatites Virales CO3 Aquitaine Cohort, 2012-2014.

    PubMed

    Cazanave, Charles; Reigadas, Sandrine; Mazubert, Cyril; Bellecave, Pantxika; Hessamfar, Mojgan; Le Marec, Fabien; Lazaro, Estibaliz; Peytavin, Gilles; Bruyand, Mathias; Fleury, Hervé; Dabis, François; Neau, Didier

    2015-01-01

    Background.  The purpose of this study was to assess the efficacy and tolerability of combined antiretroviral therapy (cART) in human immunodeficiency virus (HIV)-1 virologically suppressed patients who switched to rilpivirine (RPV)/tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC) as a single-tablet regimen (STR). Methods.  A retrospective multicenter cohort study was performed between September 2012 and February 2014 in Bordeaux University Hospital-affiliated clinics. Patients with a plasma HIV viral load (VL) lower than 50 copies/mL and switching to STR were evaluated at baseline, 3, 6, 9, and 12 months from switch time (M3, M6, M9, M12) for VL and other biological parameters. Change from baseline in CD4 cell counts was evaluated at M6 and M12. Virological failure (VF) was defined as 2 consecutive VL >50 copies/mL. Results.  Three hundred four patients were included in the analysis. Single-tablet regimen switch was proposed to 116 patients with adverse events, mostly efavirenz (EFV)-based (n = 59), and to 224 patients for cART simplification. Thirty of 196 patients with available genotype resistance test results displayed virus with ≥1 drug resistance mutation on reverse-transcriptase gene. After 12 months of follow-up, 93.4% (95.5% confidence interval, 89.9-96.2) of patients remained virologically suppressed. There was no significant change in CD4 cell count. During the study period, 5 patients experienced VF, one of them harboring RPV resistance mutation. Clinical cART tolerability improved in 79 patients overall (29.9%) at M6, especially neurological symptoms related to EFV. Fasting serum lipid profiles improved, but a significant estimated glomerular function rate decrease (-11 mL/min/1.73 m(2); P < 10(-4)) was observed. Conclusions.  Overall, virologic suppression was maintained in patients after switching to RPV/TDF/ FTC. This STR strategy was associated with improved tolerability.

  15. Diagnostic Tools for Plasma Wind Tunnels and Reentry Vehicles at the IRS

    DTIC Science & Technology

    2000-04-01

    34Massenspektrometrie zur Unter- suchung lichtbogenbeheizter Plasmen in Niederdruck - Plasmawindkanal", Dissertation, Universitfit Stuttgart, 1994. [A.4...A., "Massenspektrometrie zur plasma condition: Untersuchung lichtbogenbeheizter Plasmen in Niederdruck -Plasmawindkanal", Dissertation, qradiation

  16. Multi-Scale Autoregressive Processes

    DTIC Science & Technology

    1989-06-01

    rationnelles et leurs langages," Mas- son 1984, Collection "Etudes et Recherches en Informatique". [12] J.L. DUNAU, "Etude d’une classe de marches...June 1989 LIDS-P-1880 Multi-Scale Autoregressive Processes Michele Basseville’ Albert Benveniste’ Institut de Recherche en Informatique et Systemes...Centre National de la Recherche Scientifique (CNRS) and A.B. is also with Institut National de Recherche en Informatique et en Automatique (INRIA). The

  17. Ein Unscented Kalman Filter zur Schätzung von Schaltungsnichtidealitäten eines zeitkontinuierlichen Sigma-Delta Wandlers mit impliziter Dezimation

    NASA Astrophysics Data System (ADS)

    Buhmann, A.; Keller, M.; Maurer, M.; Ortmanns, M.; Manoli, Y.

    2008-05-01

    Nichtidealitäten einer Schaltung, wie z.B. nicht ideale Charakteristik des Operationsverstärkers und Streuungen in den Filterkoeffizienten, sind dahingehend bekannt die Effizienz von zeitkontinuierlichen Sigma-Delta Wandlern in drastischer Weise zu reduzieren. Daher stellt diese Veröffentlichung eine mögliche Methode vor, um die genannten Nichtidealitäten durch eine Schätzung mit Hilfe eines Unscented Kalman Filters zu bestimmen und in einem möglichen weiteren Schritt zu korrigieren. Des Weiteren kann durch eine leichte Modifikation des vorgestellten Algorithmus auch gleichzeitig eine implizite Dezimation des Ausgangssignals durchgeführt werden. Hierdurch wird die Gesamteffizienz des vorgestellten Ansatzes gesteigert, da kein zusätzlicher Dezimationsfilter mehr benötigt wird. Simulationsergebnisse des Filteralgorithmus zeigen die prinzipielle Funktion des Algorithmus.

  18. Monte Carlo Simulationen der kosmischen Bestrahlung planetarer Oberflächen und Anwendung zur geochemischen Analyse Neutronen-induzierter Gammaspektren des Mars.

    NASA Astrophysics Data System (ADS)

    Dagge, G.

    1991-09-01

    A Monte Carlo procedure for the simulation of the cosmic irradiation of planetary surfaces was developed by using the HERMES code system. The calculation procedure was successfully tested on experimental data from the lunar surface. The neutron and gamma-ray spectrum emitted from the martian surface was simulated for a variety of possible material compositions. These calculations are the basis for the analysis of future data from orbital neutron and gamma-ray spectroscopy with respect to the martian surface composition. A main aspect of these studies was the detection of water in the martian soil. The surface can be investigated to depths of 100 g/cm2 by this method. The background signal at the detector site was calculated in order to show that the complete martian surface can be analyzed within a given time of one martian year.

  19. Grüne Infrastruktur -. Konzepte und Strategien zur Förderung eines Bewusstseins für den Wert von Stadtgrün

    NASA Astrophysics Data System (ADS)

    Menke, Peter

    2016-06-01

    Due to climate change, but also because of the demographic change and financial constraints in many municipalities, the future of cities is a currently much-discussed topic. Conflicts over land-use are inevitable: As densification is an essential principle in growing cities, the pressure on open (green) spaces rises. Climate Change and water-management as well as mobility-issues and air-quality confront municipalities with new challenges, in terms of open space planning and greenery in the city. It is necessary to save the existing green in these days of budget-shortage and other priorities in communities. Municipalities have to raise new strategies to strengthen the awareness of the value of green in public and in the local business.

  20. Aspektanalysen von Fernsehaufzeichnungen. Ein Beitrag zur Lehrproben-Situation (Aspect Analyses of Television Tapes. A Contribution to the Practice Teaching Situation)

    ERIC Educational Resources Information Center

    Breitkreuz, Hartmut

    1975-01-01

    For improvement of practice teaching, this article suggests use and evaluation of television tapes, deriving from these a vocabulary of teaching and "aspect analyses." A catalog of these is given; a list of TV tapes for teaching English, with their availability, is also provided. (Text is in German.) (IFS/WGA)

  1. Stadtgrün statt Stress. Eine epidemiologische Studie zur gesundheitlichen Bedeutung urbaner Ökosystemleistungen am Beispiel der Stadt Bonn

    NASA Astrophysics Data System (ADS)

    Ptock, Alexandra

    2016-06-01

    The study shows the relation between urban green and (urban) stress within the urban district Bonn, Germany. How do urban ecosystem services influence the subjective well-being? A triangulation of methods (site's inspections, online survey) was applied to collect data on the availability and state of urban green spaces regarding the urban district of Bonn and by whom, why and how often they are visited. Of special interest could be the ecological state of the green space. The ecological state of green spaces in Bonn was assessed and connected to the results of the online survey. Thus, health effective potentials of urban green can be given. Main advantages were proved by an excellent network of green infrastructure as well as big green spaces or rather open catchment areas.

  2. Urbanisierung und Ökologische Stadtentwicklung. Zur Integration urbaner Biodiversität und Ökosystemleistungen in Deutschland und China

    NASA Astrophysics Data System (ADS)

    Kümper-Schlake, Lennart

    2016-06-01

    Urbanisation processes increase land-use conflicts and ecosystem destruction globally. Especially in China, a country with an outstanding urbanization rate, city governments are challenged by environmental and health problems. Urban green spaces - subsequently defined as urban biodiversity and ecosystem services - can minimize numerous environmental risks and at the same time contribute to the citizens' well-being and quality of life. In this highly relevant field of nature conservation, geographical perspectives are required - in science, politics, policy, planning and practice.

  3. Arthur Beer and his relations to Einstein and to the Warburg library (German Title: Arthur Beer und seine Beziehungen zu Einstein und zur Warburg-Bibliothek)

    NASA Astrophysics Data System (ADS)

    Duerbeck, Hilmar W.; Beer, Peter

    We give an account of the scientific life of Arthur Beer (1900-1980). Born in Reichenberg, Bohemia, he studied in Leipzig, Vienna and Berlin. After obtaining his Ph.D., he worked with the Seewarte (maritime observatory) and with the Warburg Library, both in Hamburg. Because of his relations with Finlay Freundlich, Einstein and Fritz Saxl, he succeeded in emigrating to England in 1934, where he obtained a temporary position at Cambridge Observatory, and carried out astrophysical research under F.J.M. Stratton. After shorter stays at the observatories of Mill Hill and Kew, both in the vicinity of London, he obtained, after World War II, the position of Senior Assistant Observer in Cambridge. Besides his studies in astrophysics and the history of astronomy, he is best known as the founding editor of the series "Vistas in Astronomy".

  4. Hydraulische Optimierung des Reaktionsraumes um einen Infiltrationsbrunnen zur unterirdischen Enteisenung - Durchführung eines Feldversuchs mit Infiltrationssteuerung (Teil 2/2)

    NASA Astrophysics Data System (ADS)

    Bartak, Rico; Macheleidt, Wolfgang; Ahrns, Johannes; Grischek, Thomas

    2017-08-01

    In subsurface iron removal (SIR), oxygen-enriched water is injected into an aquifer to create a reaction zone. Ahrns et al. (2017) simulated a doubling of the efficiency coefficient by the inactivation of well screen sections during injection for a vertical SIR pilot well penetrating an aquifer with varying dissolved iron concentrations. The optimized injection regime was adopted conceptually in a pilot SIR test. An inflatable packer was used to manipulate the outflow distribution. The packer was inflated before the injection phase then evacuated with a vacuum pump before pumping while remaining inside the casing. Cycles with conventional injection were performed first and iron breakthrough was monitored in the pumped water. Subsequently when the packer was used, iron removal increased by 25% and the efficiency coefficient by 50% for an adopted reference value of 5.0 mg/l. Although the study site was unfavorable for SIR because of the unfavorable low alkalinity (pH in the re- and infiltrate decreased down to 4.2), the injectant could have been pretreated by the addition of alkalis prior to injection. This was not considered in the simulation and iron concentrations were above the limits commonly used in practice. However, the overall use of an optimized injection will still be presented.

  5. Implementierung eines Rolling Horizon Ansatzes zur Anwendung bei der Lokomotiveneinsatzoptimierung (Implementation of a Rolling Horizon Approach to its Application for Locomotive Scheduling)

    DTIC Science & Technology

    2016-01-01

    Kooperationspartners Deutsche Bahn 1 1.2. Motivation und Ziel der Arbeit 2 1.3. Aufbau der Arbeit . . . . 3 2. Mathematischen Grundlagen 4 2.1...RHH Tfz VR VRP VSP Aircraft Sequencing Problem Baureihe Deutsche Bahn First In First Out Abteilung Verkehrsnetzentwicklung und Verkehrsmodelle...zuerst der Kooperationspartner vorgestellt und im Anschluss auf die Problemstellung eingegangen. 1.1. Vorstellen des Kooperationspartners Deutsche

  6. Briefkasten oder Brieftaube? Zur Auswahl der Lexik in amerikanischen Deutschlehrwerken fuer die Grundstufe. ("Mailbox" or "Carrier Pigeon"? Selecting Vocabulary for American College-Level Elementary German Textbooks).

    ERIC Educational Resources Information Center

    Bolton, Sibylle

    A comparison of four college-level elementary German textbooks reveals significant differences in the numbers of vocabulary entries in each textbook. Further comparison of three of the textbooks with the basic German vocabulary lists provided in "Kontaktschwelle Deutsch als Fremdsprache" and in "Das Zertificat Deutsch als Fremdsprache" reveal in…

  7. Internationality from the VAG (1800) to the Astronomische Gesellschaft. (German Title: Internationalität von der VAG (1800) bis zur Astronomischen Gesellschaft)

    NASA Astrophysics Data System (ADS)

    Wolfschmidt, Gudrun

    Organized internationalization in astronomy started with a first meeting of 15 European astronomers in Gotha in 1798. Two years later the ``Vereinigte Astronomische Gesellschaft'' (VAG) was founded in Lilienthal near Bremen, to organize the compilation of ecliptic star charts for finding the missing planet between Mars and Jupiter. Cooperation was also planned for observing comets and variable stars. More than half of the members originated from non-German speaking countries. In 1800, the ``Monatliche Correspondenz'' was founded by Franz Xaver von Zach to publish the results. In 1857, the problem of analyzing the increasing amount of asteroid observations came up in the ``Section Geographie und Astronomie'' (founded in 1828) of the ``Gesellschaft Deutscher Naturforscher und Ärzte'', and was further discussed in 1860 and 1861. From these two roots mentioned, the ``Astronomische Gesellschaft'' (AG) was founded in Heidelberg in 1863 - again internationally structured: 11 out of 26 members were from foreign observatories, and until the 1930s well over 50% of the members were foreigners - the maximum was 65% in 1880. The main aim was again international cooperation, particularly in compiling various catalogues and bibliographies (AGK1 and GuL). The ``International Union for Cooperation in Solar Research'' (ISU) and the ``International Astronomical Union'' (IAU) were founded in 1904 and in 1919, respectively. A difficult situation arose after World War I, when the allied countries were not allowed to be members until 1928. But the international organizations, the AG and the IAU, co-existed because they had different goals. Thanks especially to the Swedish astronomer Svante Elis Strömgren, who was elected president, the ``Astronomische Gesellschaft'' still flourished through the 1920s.

  8. Berufliche Bildung in den USA - Von der Werkbank zur Schulbank (Vocational Education in the United States - from the Work Bench to the School Desk).

    ERIC Educational Resources Information Center

    Kreysing, Matthias

    2002-01-01

    Presents an account of the history of U.S. vocational education. Emphasizes the tension between the two fundamental concepts underlying vocational education: the pedagogical and sociopolitical perspective and the economic interests. Reflects the conflict in the debate on the form of vocational education: work based or school based. (CAJ)

  9. Evolutionäre Algorithmen zur Topologieentwicklung von Neuronalen Netzen für die Roboter-Navigation im praktischen Einsatz

    NASA Astrophysics Data System (ADS)

    Köpsel, T.; Noglik, A.; Pauli, J.

    Eine wichtige Frage in der mobilen Robotik ist die sichere Navigation in unbekannten Umgebungen unter der Anwendung preiswerter Sensorik. Solch eine Navigation kann ein künstliches Neuronales Netz (kNN) übernehmen, welches die Kopplung der Sensoren des Roboters mit dessen Antriebssystem herstellt. "Neuro Evolution of Augmenting Topologies“ (NEAT) von Stanley und Miikkulainen [1] verwendet den Evolutionären Ansatz sowohl für die Topologieentwicklung, als auch für die Bestimmung der Gewichte eines kNN. NEAT hat sich als sehr gut, anpassungsfähig und relativ einfach in der Anwendung gezeigt. In diesem Beitrag wird NEAT in der Simulation angewendet, um ein kNN, das die Navigation des Roboters übernimmt, zu erhalten. Der Fokus liegt dabei auf der Erstellung der Fitnessfunktion und die Spezifikation und Durchführung einer realitätstreuen Simulation für den praktischen Einsatz. Die enge Verknüpfung von Realität und Simulationswelt hat entscheidend dazu beigetragen, dass der Umstieg aus der Simulation in die reale Welt ein Erfolg (höhere Anpassungsfähigkeit) wird. Dieser Artikel basiert auf der Diplomarbeit von [2].

  10. Zur Frage der Textauswahl in einem Lesekurs fuer die Sozialwissenschaften (On the Question of the Choice of Textbooks in a Course in the Social Sciences)

    ERIC Educational Resources Information Center

    Apelt, Hans-Peter

    1974-01-01

    Passages from three selected samples of textbooks are used to show what requirements are made of textbooks in the social sciences. Some hints are given to the teacher for converting reading suggestions into instructional material. Short texts from Karl Marx are also suggested. (Text is in German.) (IFS/WGA)

  11. Bildung und bildungstheoretische Ueberlegungen zur Grundung der Republik (Education and the Republic--Educational Theorists Reflections on the Foundation of the Republic).

    ERIC Educational Resources Information Center

    Hellekamps, Stephanie

    1996-01-01

    Draws on Wilhelm von Humboldt's typology of the active human being to debate the questions whether and how individuals can produce their social and political world. Discusses, with reference to Marie Condorcet and Immanuel Kant, procedures of the public that are necessary prerequisites for actions aimed at forming the world. (DSK)

  12. Wortbildung und Fremdsprachenunterricht. Ein Beitrag zur Vermittlung zwischen Theorie und Praxis [Word Formation and Foreign Language Teaching. A Contribution to Bridging between Theory and Practice (Part 2)].

    ERIC Educational Resources Information Center

    Storch, Guenther

    1979-01-01

    Only regular word-building patterns are considered. Patterns are chosen for their communicative value, degree of difficulty, and applicability. Examples of word-building exercises are given, taken from actual texts. Work in word formation is recommended even for the beginners' level. (IFS/WGA)

  13. Wortbildung und Fremdsprachenunterricht. Ein Beitrag zur Vermittlung zwischen Theorie und Praxis [Word Formation and Foreign Language Teaching. A Contribution to Bridging between Theory and Practice (Part 1)].

    ERIC Educational Resources Information Center

    Storch, Guenther

    1979-01-01

    Sees word formation as an economical, important means of building vocabulary. Gives examples showing several different word-building patterns. Sees as a reasonable teaching goal the gaining of competence only in "receptive" word formation, i.e., recognition. The student can learn to build new words only from simple, frequently recurring…

  14. European Consciousness: Towards Defining a Complex Concept and Its Educational Significance (Europaisches Bewusstsein: Zur Definition Eines Vielschichtigen Begriffes und Seiner Bildungstheoretischen Bedeutung)

    ERIC Educational Resources Information Center

    Jobst, Solvejg

    2005-01-01

    The present study aims at a definition of "European consciousness". In particular, it draws on Henri Tajfel's theory of social identity as well as Roland Wakenhut's and Jutta Gallenmuller's moral determination of national consciousness. European consciousness is then defined as a sense of belonging which, depending on certain…

  15. Kooperatives Lernen lernen? Zur Diskussion uber das Bildungswesen in Japan (Learning Cooperative Learning? On the Discussion of the Japanese Educational System).

    ERIC Educational Resources Information Center

    Schubert, Volker

    1998-01-01

    Suggests a reconsideration of the criticism of Japanese competition against the background of the Japanese educational system's highly developed learning culture. Considers some of the basic aspects of group-oriented communal learning in school, while also cautioning against a "monocausal" culturalism. (Author/CMK)

  16. Zur Kategorie der Modalitaet im Deutschen und Tschechischen aus konfrontativer Sicht (On the Category of Modality in German and Czech, Viewed in Comparison and Contrast)

    ERIC Educational Resources Information Center

    Grepl, Miroslav; Masarik, Zdenek

    1974-01-01

    Rejects a too-general classification of modality; would omit emotionality, affirmations and negations. Particles should not be indiscriminately classed as modals. Modality is divided into three aspects, which are then explained, with numerous comparative examples in Czech and German. (Text is in German.) (IFS/WGA)

  17. Pragma- und textilinguistische Untersuchungsmethoden zur indirekten Rede im Englischen (Pragmatic and Text-Linguistic Research Methods on Indirect Discourse in English)

    ERIC Educational Resources Information Center

    Ziegesar, Detlef von

    1976-01-01

    Examines the mechanisms involved in changing from direct to indirect discourse, taking as a starting point research findings in linguistic pragmatics, which involve the practical application of speech symbol use between speaker and hearer. (Text is in German.) (IFS/WGA)

  18. Untersuchung von Methoden zur ldentifikation der zeit und frequenzabhangigen Netzimpedanz (Investigation of Methods for the Identification of Time and Frequency dependent Network Impedances) Impedances

    DTIC Science & Technology

    2016-10-01

    Wissenschaftlicher Tatigkeitsnachweis 169 vii Nomenklatur Verwendete Abki.irzungen AAF AC ADC CAD DC DFT DNL DPLL DSP DUT EE EEA EEG EMV...Gesetz ( EEG ) von 2000 [BGBIOO] und dessen Novellierungen [BGB104),[BGB108],[BGB111],[BGB112] [BGB114] ein rasanter Ausbau der EE bei der...Elektroenergieversorgung eingeleitet. Das EEG garantiert eine bevorzugte Netzeinspeisung mit festen Vergiitungssiitzen fur die Stromerzeugung aus erneuerbaren

  19. Kooperatives Lernen lernen? Zur Diskussion uber das Bildungswesen in Japan (Learning Cooperative Learning? On the Discussion of the Japanese Educational System).

    ERIC Educational Resources Information Center

    Schubert, Volker

    1998-01-01

    Suggests a reconsideration of the criticism of Japanese competition against the background of the Japanese educational system's highly developed learning culture. Considers some of the basic aspects of group-oriented communal learning in school, while also cautioning against a "monocausal" culturalism. (Author/CMK)

  20. Bildung und bildungstheoretische Ueberlegungen zur Grundung der Republik (Education and the Republic--Educational Theorists Reflections on the Foundation of the Republic).

    ERIC Educational Resources Information Center

    Hellekamps, Stephanie

    1996-01-01

    Draws on Wilhelm von Humboldt's typology of the active human being to debate the questions whether and how individuals can produce their social and political world. Discusses, with reference to Marie Condorcet and Immanuel Kant, procedures of the public that are necessary prerequisites for actions aimed at forming the world. (DSK)

  1. Arbeit mit einer schulfunkreihe im englischunterricht mit lernschwaecheren Schuelern. Anregungen zur Weiterentwicklung der Schulfunkarbeit (Working with a School Radio Series In Teaching English to Weaker Students).

    ERIC Educational Resources Information Center

    Bebermeier, Hans

    1979-01-01

    School radio is useful if it has motivating power and can be understood and acted out by the students. The series "English for Juniors" is recommended as an example. Methodological points for the teaching of weaker students are presented. (IFS/WGA)

  2. Qualitat Fur Wen? Zur Angemessenheit des Kundenbegriffs in der Sozialen Arbeit (Quality for Whom? On the Adequacy of the Concept of the Customer in Social Work).

    ERIC Educational Resources Information Center

    Nussle, Werner

    2000-01-01

    States that in the debate on quality management the concept of the customer and the issue of social work being considered as part of the services sector play a crucial role. Argues that not enough attention is paid to the dangers inherent in the transfer to the customer concept. (CMK)

  3. Zur Frage der Textauswahl in einem Lesekurs fuer die Sozialwissenschaften (On the Question of the Choice of Textbooks in a Course in the Social Sciences)

    ERIC Educational Resources Information Center

    Apelt, Hans-Peter

    1974-01-01

    Passages from three selected samples of textbooks are used to show what requirements are made of textbooks in the social sciences. Some hints are given to the teacher for converting reading suggestions into instructional material. Short texts from Karl Marx are also suggested. (Text is in German.) (IFS/WGA)

  4. European Consciousness: Towards Defining a Complex Concept and Its Educational Significance (Europaisches Bewusstsein: Zur Definition Eines Vielschichtigen Begriffes und Seiner Bildungstheoretischen Bedeutung)

    ERIC Educational Resources Information Center

    Jobst, Solvejg

    2005-01-01

    The present study aims at a definition of "European consciousness". In particular, it draws on Henri Tajfel's theory of social identity as well as Roland Wakenhut's and Jutta Gallenmuller's moral determination of national consciousness. European consciousness is then defined as a sense of belonging which, depending on certain…

  5. Aspektanalysen von Fernsehaufzeichnungen. Ein Beitrag zur Lehrproben-Situation (Aspect Analyses of Television Tapes. A Contribution to the Practice Teaching Situation)

    ERIC Educational Resources Information Center

    Breitkreuz, Hartmut

    1975-01-01

    For improvement of practice teaching, this article suggests use and evaluation of television tapes, deriving from these a vocabulary of teaching and "aspect analyses." A catalog of these is given; a list of TV tapes for teaching English, with their availability, is also provided. (Text is in German.) (IFS/WGA)

  6. Briefkasten oder Brieftaube? Zur Auswahl der Lexik in amerikanischen Deutschlehrwerken fuer die Grundstufe. ("Mailbox" or "Carrier Pigeon"? Selecting Vocabulary for American College-Level Elementary German Textbooks).

    ERIC Educational Resources Information Center

    Bolton, Sibylle

    A comparison of four college-level elementary German textbooks reveals significant differences in the numbers of vocabulary entries in each textbook. Further comparison of three of the textbooks with the basic German vocabulary lists provided in "Kontaktschwelle Deutsch als Fremdsprache" and in "Das Zertificat Deutsch als Fremdsprache" reveal in…

  7. Zur eignung warmfester vergütungsstähle mit 9 bis 12% chrom für komponenten im kern schneller reaktoren — ein überblick

    NASA Astrophysics Data System (ADS)

    Anderko, K.

    1980-11-01

    Heat-resisting martensitic 12% chromium steels are considered as alternative materials for application as fuel-element components such as wrappers in the liquid sodium cooled fast breeder reactor. This type of steel appears to have certain important advantages in comparison with austenitic stainless steels as far as the response to heavy neutron irradiation is concerned. The published information on the swelling and in-pile creep behaviour and on the influence of irradiation on tensile, creep and impact properties has been reviewed. Very promising results are available as to void swelling resistance and creep strength and ductility. On the other hand, data on the effect of high neutron doses on the impact strength, on the irradiation creep behaviour and on the structural stability are still missing so that the potential of this type of steel cannot yet finally be judged.

  8. Zur Afuwertung der Kultur- und Landeskunde. Ein Literaturbericht (Toward an Evaluation of Culture Studies and Other Area Studies. A Survey of the Literature)

    ERIC Educational Resources Information Center

    Hartig, Paul

    1975-01-01

    Eight recent monographs and collections on area and culture study in foreign language teaching are discussed and compared. The focus is on the various authors' definitions of the topic (culture, civilization, realia, etc.). Mentioned also is the function of area study in the course. (Text is in German.) (IFS/WGA)

  9. Empirische Verfahren zur Ableitung verschiedener Porositätsarten aus Durchlässigkeitsbeiwert und Ungleichkörnigkeitszahl - ein Überblick

    NASA Astrophysics Data System (ADS)

    Fuchs, Sven; Ziesche, Michael; Nillert, Peter

    2017-06-01

    This paper comprises a review of the 13 studies that have been proposed for the derivation of porosity, effective porosity and/or specific yield from grain size distributions (Lejbenson 1947; Istomina 1957; Beyer 1964; Hennig 1966; Golf 1966; Marotz 1968; Beyer und Schweiger 1969; Seiler 1973; Bureau of Reclamation 1984; Helmbold 1988; Beims und Luckner 1999; Balke et al. 2000; Helmbold 2002). Experimental design, limitations and application boundaries are discussed and methods are compared against each other. The quality of the predictive methods strongly depends on the experimental design and the sample type.

  10. Pragma- und textilinguistische Untersuchungsmethoden zur indirekten Rede im Englischen (Pragmatic and Text-Linguistic Research Methods on Indirect Discourse in English)

    ERIC Educational Resources Information Center

    Ziegesar, Detlef von

    1976-01-01

    Examines the mechanisms involved in changing from direct to indirect discourse, taking as a starting point research findings in linguistic pragmatics, which involve the practical application of speech symbol use between speaker and hearer. (Text is in German.) (IFS/WGA)

  11. Ein eingebettetes Expertensystem zur Automatisierung der VLBI-Auswertung %t An embedded expert system for the automation of the VLBI data analysis

    NASA Astrophysics Data System (ADS)

    Schwegmann, Wolfgang

    2004-01-01

    Since its first application in the seventies geodetic Very Long Baseline Interferometry has become an important technique for geodesy, astronomy and geophysics. The goal of this thesis is the design and implementation of a system to automate the entire VLBI analysis procedure. On the one hand this allows to close the gap between the time of observation and the availability of results, on the other hand the few existing experts will be relieved from their routine burdens. To achieve this, knowledge-based methods from the field of research of artificial intelligence are used. An Intelligent Assistant for Data Analysis in VLBI (IADA) is developed as an embedded expert system. The term "embedded" is of particular interest, because embedding expert systems in the existing data processing environment is critical for the success of such a system. Embedding IADA in the existing analysis software by building a powerful interface guarantees the automation of the whole VLBI analysis procedure. The strong connection between the existing analysis software and the expert system developed here is an important contribution of the thesis, because generally expert systems suffer from the missing connections to the existing data processing environment.

  12. Einleitung

    NASA Astrophysics Data System (ADS)

    Zahoransky, Richard; Allelein, Hans-Josef; Bollin, Elmar; Oehler, Helmut; Schelling, Udo

    Mit der Beherrschung der Energie, zunächst des Feuers, schaffte sich die Menschheit die Basis zur technischen und wirtschaftlichen Entwicklung. Energie in ihren verschiedenen Erscheinungsformen ist zur Nahrungszubereitung, zum Wohnen, zum Transport, zur Kommunikation, in der Technik, Industrie und in der Freizeit unverzichtbar. Energie gehört zu den Grundbedürfnissen.

  13. The transcriptional regulator Np20 is the zinc uptake regulator in Pseudomonas aeruginosa.

    PubMed

    Ellison, Matthew L; Farrow, John M; Farrow, John Matthew; Parrish, Whitney; Danell, Allison S; Pesci, Everett C

    2013-01-01

    Zinc is essential for all bacteria, but excess amounts of the metal can have toxic effects. To address this, bacteria have developed tightly regulated zinc uptake systems, such as the ZnuABC zinc transporter which is regulated by the Fur-like zinc uptake regulator (Zur). In Pseudomonas aeruginosa, a Zur protein has yet to be identified experimentally, however, sequence alignment revealed that the zinc-responsive transcriptional regulator Np20, encoded by np20 (PA5499), shares high sequence identity with Zur found in other bacteria. In this study, we set out to determine whether Np20 was functioning as Zur in P. aeruginosa. Using RT-PCR, we determined that np20 (hereafter known as zur) formed a polycistronic operon with znuC and znuB. Mutant strains, lacking the putative znuA, znuB, or znuC genes were found to grow poorly in zinc deplete conditions as compared to wild-type strain PAO1. Intracellular zinc concentrations in strain PAO-Zurzur) were found to be higher than those for strain PAO1, further implicating the zur as the zinc uptake regulator. Reporter gene fusions and real time RT-PCR revealed that transcription of znuA was repressed in a zinc-dependent manner in strain PAO1, however zinc-dependent transcriptional repression was alleviated in strain PAO-Zur, suggesting that the P. aeruginosa Zur homolog (ZurPA) directly regulates expression of znuA. Electrophoretic mobility shift assays also revealed that recombinant ZurPA specifically binds to the promoter region of znuA and does not bind in the presence of the zinc chelator N,N',N-tetrakis(2-pyridylmethyl) ethylenediamine (TPEN). Taken together, these data support the notion that Np20 is the P. aeruginosa Zur, which regulates the transcription of the genes encoding the high affinity ZnuABC zinc transport system.

  14. The Transcriptional Regulator Np20 Is the Zinc Uptake Regulator in Pseudomonas aeruginosa

    PubMed Central

    Ellison, Matthew L.; Farrow, John Matthew; Parrish, Whitney; Danell, Allison S.; Pesci, Everett C.

    2013-01-01

    Zinc is essential for all bacteria, but excess amounts of the metal can have toxic effects. To address this, bacteria have developed tightly regulated zinc uptake systems, such as the ZnuABC zinc transporter which is regulated by the Fur-like zinc uptake regulator (Zur). In Pseudomonas aeruginosa, a Zur protein has yet to be identified experimentally, however, sequence alignment revealed that the zinc-responsive transcriptional regulator Np20, encoded by np20 (PA5499), shares high sequence identity with Zur found in other bacteria. In this study, we set out to determine whether Np20 was functioning as Zur in P. aeruginosa. Using RT-PCR, we determined that np20 (hereafter known as zur) formed a polycistronic operon with znuC and znuB. Mutant strains, lacking the putative znuA, znuB, or znuC genes were found to grow poorly in zinc deplete conditions as compared to wild-type strain PAO1. Intracellular zinc concentrations in strain PAO-Zurzur) were found to be higher than those for strain PAO1, further implicating the zur as the zinc uptake regulator. Reporter gene fusions and real time RT-PCR revealed that transcription of znuA was repressed in a zinc-dependent manner in strain PAO1, however zinc-dependent transcriptional repression was alleviated in strain PAO-Zur, suggesting that the P. aeruginosa Zur homolog (ZurPA) directly regulates expression of znuA. Electrophoretic mobility shift assays also revealed that recombinant ZurPA specifically binds to the promoter region of znuA and does not bind in the presence of the zinc chelator N,N′,N-tetrakis(2-pyridylmethyl) ethylenediamine (TPEN). Taken together, these data support the notion that Np20 is the P. aeruginosa Zur, which regulates the transcription of the genes encoding the high affinity ZnuABC zinc transport system. PMID:24086521

  15. A brief history of genome research and bioinformatics in France.

    PubMed

    Danchin, A

    2000-01-01

    The development of in silico genomics has progressed slowly in France for a number of political reasons. Two administrative organizations, the Groupement de Recherche sur les Génomes (GREG) and the Groupement de Recherche 1029 (GDR 1029) of the Centre National de la Recherche Scientifique (CNRS) have been established. These organizations have created the dynamics that hopefully will place France (which coordinated consortia that completed several of the first large microbial genomes) among the developed nations that support Large-Scale Biology.

  16. PMD basierte Fahrspurerkennung und -Verfolgung für Fahrerassistenzsysteme

    NASA Astrophysics Data System (ADS)

    Gumpp, T.; Schamm, T.; Bergmann, S.; Zöllner, J. M.; Dillmann, R.

    In diesem Artikel wird ein System zur Verfolgung von Fahrspuren unter Verwendung von PMD-Kameras vorgestellt. Er gibt einen überblick über die Auswertung der Intensitäts- und Tiefenbilder dieses Sensors in einem System zur fremdlichtunabhängigen Fahrspurverfolgung. Ein Kaiman-Filter wird verwendet, um neben den Fahrspurparametern auch die Position und Orientierung des Fahrzeugs relativ zur Fahrspur zu schätzten.

  17. Optimal Active Sound-Reduction in Airplane-Cubicles for High Tonal Noise-Levels (optimale aktive gerauschreduzierung in flugzeugkabinen fur hohe tonale larmpegel)

    DTIC Science & Technology

    2005-08-01

    Reglerpara meters .............................................. 21 3.2 Ausgew~ hlter Algorithmus zur Vorw~rtsf0hrung...q Lq_. Abb. 3. 1: Paretokunve for elne Kon figuration 3.2 Auspew~ hlter Alporithmus zur Vorw~rtsf~hrung For die Regelung wird der for ANC-Systeme...n) =X T (n) -w(n). (3.14) 3.2. Ausgew~ hlter Algorithmus zur Vorw~rtsf~hrung 25 Das geregelte Schallfeld ergibt sich mit * als Faltungsoperator und aus

  18. Modellgestützte Ladedruck- und Abgasrückführ-Regelung von Dieselmotoren

    NASA Astrophysics Data System (ADS)

    von Pfeil, Karl

    Zur Erfüllung der Abgasgesetzgebung bei gleichzeitiger hoher Fahrleistung und Beschleunigung sind moderne Pkw-Dieselmotoren mit externer Abgasrückführung (AGR) und mit Abgasturbolader mit variabler Turbinengeometrie (VTG) ausgestattet, siehe Bild 10-1. Der über ein Ventil stellbare AGR-Massenstrom wird zur Senkung der Stickoxidemissionen eingesetzt und der Turbolader wird hauptsächlich zur Steigerung des Ladedrucks und damit zur Leistungssteigerung verwendet. Mittels VTG wird der Turbolader an den Motorbetriebspunkt angepasst. Hierzu wird über einen elektrisch oder pneumatisch betätigten Aktor die Turbinenleitschaufelstellung und damit die wirksame Turbinenströmung verstellt.

  19. Optimale Schulanfangszeiten zur Entlastung des Nah verkehrs in der Stadt Nuernberg (Optimal Times for the Beginning of Schools to Reduce the Pressure on Public Transport in the City of Nuremberg)

    DTIC Science & Technology

    2016-01-01

    Entlastung des Nah verkehrs in der Stadt 1\\-iimberg (Optimal Times for the Beginning of Schools to Reduce the Pressure on Public T ransport in the City of N...of different school starting times. In a city like Niinberg for example, with an average of730 students per school and 70 schools across the city...switch to private cars, hold it low the exhaust pollution and thus protects health and the environment. Thi s is possible at the same time, through

  20. Medienerziehung und Projektmethode. Zur Theorie und Praxis handlungsorietierten Unterrichts am Beispiel "Zeitung in der Schule" (Media Education and Project Method--On the Theory and Practice of Action-Oriented Instruction as Illustrated by the Project "Newspaper and School").

    ERIC Educational Resources Information Center

    Brunhold, Andreas

    2000-01-01

    States that the daily newspaper holds an important place in society although it has experienced increased competition from the electronic media market. Contends that schools need to transmit media competencies, explaining that a newspaper project is an ideal means for imparting media competencies since students are acquainted with this medium.…

  1. Von der Kulturkunde zur Landeskunde: Geschichte und Probleme eines Aspekts des Fremdsprachenunterrichts aus deutscher Sicht (From Culture to Country: History and Problems of an Aspect of Foreign Language Teaching from a German Point of View)

    ERIC Educational Resources Information Center

    Gutschow, Harald

    1977-01-01

    Currently some skepticism exists concerning the value of area studies--especially the concept of "national traits." Also, the alleged motivational value may be offset by the sacrifice of language-learning time. German language teaching has followed the U.S. lead; American teachers might profit from German experience. (Text is in German.) (WGA)

  2. Hinweise zur Mitarbeiterfortbildung: 5. Wiesbadener Sprachlabortagung vom 2. bis 4. Oktober 1970(Guidance on Professional Continuing Education: Proceedings of the Fifth Wiesbaden Language Laboratory Conference, October 2-4, 1970).

    ERIC Educational Resources Information Center

    Schrand, Heinrich, Ed.; Bach, Edgar, Ed.

    This report presents the results of a conference on furthering teacher education in language laboratory use. A review of recommendations for innovation, adopted at a previous conference (see FL 002 711) serves as background for summaries of papers on the following subjects: (1) foreign-language learning goals and consequences for methodology, (2)…

  3. Einige Bemerkungen ueber die Erzeugung von Elektromagnetischen Wanderwellen und Stehenden Wellen zur Induktiven Plasmabeschleunigung (Some Comments Concerning the Generation of Traveling and Standing Electromagnetic Waves for Inductive Plasma Acceleration),

    DTIC Science & Technology

    Some comments are made for the generation of electromagnetic travelling and standing waves used for inductive plasma acceleration. Resulting from a...simple mathematical formulation the different features lead to a non-conventional method for travelling wave generation, which is compared with the

  4. Entwicklung und Implementierung eines Algorithmus zur Detektion von Streuteilchen in PlV-Aufnahmen (Development and Implementation of an Algorithm for the Detection of Tracers in PlV Recordings)

    DTIC Science & Technology

    2016-01-01

    1 Auswertung gefundener Tracer . 4 Zusammenfassung Literatur 11 1 2 3 4 5 8...3 2 Particle-Image-VElocimetry 532nm output 1 064nm beam dump / 2 4 5 1 Dielectric polarizer 2 Doubling crystal 6 3 Laser mirrors and...plates 4 Output couple 7 5 Nd:YAG Rod 8 6 Q-Switch 9 7 Telescope Laser 1 Laser 2 8 Aperture 9 Rear mirror - • Abbildung 2.2: Optisches Layout

  5. Zehn Jahre nach der Wende: Elterliche Einstellungen zur Schule im Ost/West-Vergleich (Ten Years after the Fall of the GDR: A Comparison of East and West German Parental Attitudes towards School).

    ERIC Educational Resources Information Center

    Valtin, Renate; Rosenfeld, Heidrun

    2001-01-01

    Examines whether parents with elementary school children demonstrate signs of a growing dissatisfaction with elementary schools and whether there are differences between parents from East and West Berlin (Germany). Finds that parent dissatisfaction increased related to school framework conditions and that there is a difference between parents of…

  6. Die Struktur der Allgemeinbildung im Kerncurriculum moderner Bildungssysteme. Ein Vorschlag zur bildungstheoretischen Rahmung von PISA (The Structure of General Education in the Core Curriculum of Modern Educational Systems. A Proposal for a Framework for PISA Based on Educational Theory).

    ERIC Educational Resources Information Center

    Benner, Dietrich

    2002-01-01

    Draws on a theory of education for a Program for International Student Assessment (PISA) framework based on the structure of general education in modern educational systems. Shows that pedagogical research on school and instruction is formed by the relationship of instruction, didactics, curricular development, and achievement control. (CAJ)

  7. Wie konnen die Ergebnisse von vergleichenden Leistungsstudien systematisch zur Qualitatsverbesserung in Schulen genutzt werden? (How Can the Results of Large Scale Assessments Be Used Systematically for an Improvement of the Quality of Schools?).

    ERIC Educational Resources Information Center

    Terhart, Ewald

    2002-01-01

    Compares the relationship between large scale assessments and positive development of schools and instruction. Discusses strategic orientations to further quality of school systems and outlines possible starting points for the future development of individual schools. Probes the demands of a specific type of research that combines analysis and…

  8. Report on the 6th scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Oct. 31th - Nov. 2nd, 2014.

    PubMed

    Kleinschnitz, Christoph; Linker, Ralf A; Magnus, Tim; Korn, Thomas; Meuth, Sven G

    2015-01-01

    From October 31th - November 2nd, 2014, the 6th NEUROWIND e.V. meeting was held in Motzen, Brandenburg, Germany. 70 doctoral students and postdocs from over 25 different groups working in German and Swiss university hospitals or research institutes attended the meeting to discuss their latest experiments and findings in the fields of neuroimmunology, neurodegeneration and neurovascular research. The meeting was regarded as a very well organized platform to support research of young investigators in Germany and all participants enjoyed the stimulating environment for lively in depth discussions. According to the major aim of NEUROWIND e.V. to support younger researchers in Germany the 4th NEUROWIND YOUNG SCIENTIST AWARD for experimental neurology was awarded to Michael Breckwoldt on his work in the group of Thomas Misgeld (Institute of Neuronal Cell Biology, Technische Universität München, Germany). The successful project was published in Nature Medicine entitled "Multiparametric optical analysis of mitochondrial redox signals during neuronal physiology and pathology in vivo". This outstanding paper deals with a molecular imaging approach in living mice to optically analyze the role of mitochondrial redox signals in axons in health and disease. The award is endowed with 20.000 Euro sponsored by Merck Serono GmbH, Darmstadt, Germany (unrestricted educational grant). This year's keynote lecture was given by Bernhard Hemmer, Head of the Department of Neurology at the Klinikum rechts der Isar, Technische Universität München. Dr. Hemmer highlighted the particular role of B cells and (auto)antibodies in multiple sclerosis (MS). As a new highlight Dr. Urbahns, head of global discovery technologies at Merck research laboratories, gave insights from research practice in the pharmaceutical industry and introduced a shift in the view on present-day drug discovery paradigms.

  9. Die Struktur der Allgemeinbildung im Kerncurriculum moderner Bildungssysteme. Ein Vorschlag zur bildungstheoretischen Rahmung von PISA (The Structure of General Education in the Core Curriculum of Modern Educational Systems. A Proposal for a Framework for PISA Based on Educational Theory).

    ERIC Educational Resources Information Center

    Benner, Dietrich

    2002-01-01

    Draws on a theory of education for a Program for International Student Assessment (PISA) framework based on the structure of general education in modern educational systems. Shows that pedagogical research on school and instruction is formed by the relationship of instruction, didactics, curricular development, and achievement control. (CAJ)

  10. Zwischen den Stuhlen: Untersuchungen zur Situation der Korrektoren an der Fernuniversitat 1980, (In between Chairs: The Situation of Tutors (Correctors) at the FernUniversitat in 1980). ZIFF Papiere 34.

    ERIC Educational Resources Information Center

    Fritsch, Helmut; And Others

    An empirical study of tutors responsible for evaluating students' assignments at the Fernuniversitat in 1980 employed an 18-item questionnaire, analysis of open-ended responses, analysis of graders' comments on more than 1,000 assignments, and interviews with staff. The process of evaluating students' work was shown to be inefficient, with minimal…

  11. On the Situation in the Near East: Fleet Activities in the Indian Ocean: Summary from July 1980 to August 1982 (Zur Lage im Mittleren Osten: Flottenaktivataeten in Indischen Ozean: Ueberblick vom Juli 1980 bis August 1982).

    DTIC Science & Technology

    1983-05-16

    3, by Ulrich Schulz- Torge , Verlag Wehr und Wissen, Bonn, 1981. 21. Warship International, No. 4/1980, and Rivista Militare and Marine- Rundschau, No...1/1981, p. 57. 22. The Soviet Navy, Vol. 3, by Ulrich Schulz- Torge . 23. OB at 11,500 t and 150 m in length has about 400 to 500 beds and about 200

  12. orbis (sphaera), circulus, via, iter, orbita -- on the terminological identification of the essential paradigm change in astronomy by Johannes Kepler. (German Title: orbis (sphaera), circulus, via, iter, orbita} -- zur terminologischen Kennzeichnung des wesentlichsten Paradigmawechsels in der Astronomie durch Johannes Kepler)

    NASA Astrophysics Data System (ADS)

    Krafft, Fritz

    2011-08-01

    The use of modern terminology hinders to understand historical astronomical texts and often misleads the reader. Therefore, this study tries to reconstruct the ideas of the way the planets seem to move against the sphere of fixed stars in a non-teleological manner, that means in the original view and with original terms. The study proceeds historically and explains: (1) Aristotle's system of homocentric spheres being hollow spheres of ether turning equally round the earth in the centre of the world, a number of which makes the apparatus of the movement of a planet which produces its apparently unequal motion. (2) Ptolemy's reductionistic system of geometric circles (eccentric deferents, epicycles etc.), which are indeed great circles on non-concentric hollow spheres, whereupon they turn around equally. The space which they take up in all is surrounded by an inner and an outer concentric spherical surface and makes the sphere of the planet. (3) John's of Sacrobosco transferring of the geometric astronomy to the Latin of Middle Ages and the commentators' precision of the Greek-Latin terms. (4) The tradition of the "Theorica planetarum" which makes this geometry physics by allotting every partial moving to a partial material hollow sphere (with spherical surfaces of different centricity) or full sphere of an epicycle (orbes particulares or partialis), a number of which makes the entire sphere of each planet (orbis totalis or totus). - Copernicus also stood within this tradition, except that his entire spheres differ from the earlier ones in size or thickness (because he eliminated the partly very big synodic epicycles and allocated their effect as a mere parallactic one to the yearly moving of the earth) and in the great intervening spaces between each other (a result of measuring the true distances of the planets on the basis of these parallactic effects). (5) Tycho Brahe's refutation of the unchangingness and unpermeableness and therefore solidity of all etherial spheres, what had been the fundamental condition for creating the indirect ways of the planets in all astronomical systems with partial or entire spheres engaging one another. It was particularly Kepler who recognizes that as a result celestial physics requires a complete change. (6) Kepler's replacement of celestial physics. He did not think any more that the apparent (unequal) way of a planet indirectly results from the combination of several equal movements of etherial partial and entire spheres. His planets move their true and real way caused directly by the joint effect of two corporal forces moving the planets both around the sun and to and from it, which latter makes the planet's speed indeed naturally unequal. For this "real way" he coins in late 1604 the specific term "orbita" (the modern "orbit", the German "Bahn". This term then little by little replaced the former non-specific, general description of the apparent or real way (as "via, iter, ambitus, circulus, circuitus" etc.), and Kepler used it increasingly from its introduction (initially frequently joined to a describing definition of this "way") up to the exclusive use in the fifth book of the "Epitome", after this "orbita" had changed its shape from a perfect eccentric circle to an oval and finally an elliptic form. This way Kepler marks the paradigm change of astronomy caused by himself also terminologically.

  13. Video: einige Bemerkungen zum medien-spezifischen Ort und zur didaktischen Basis (Video: Some Notes on Its Place among Teaching Media and on Its Theoretical Basis in FL Teaching)

    ERIC Educational Resources Information Center

    Bauer, Hans-Ludwig

    1976-01-01

    Reports on the introduction of video recorders at various branches of the Goethe Institute. The characteristics of video are compared with those of films, tapes and printed matter. Video's advantage is that through it authentic, unprepared material can be presented, and it provides strong motivation. (Text is in German.) (IFS/WGA)

  14. Qualitatsentwicklung von Schulen in der Einwanderungsgesellschaft: Evaluation der Lehrerfortbildung zur interkulturellen Koordination (2012- 2014)(Quality Development of Schools in the Immigration Society: Evaluation of lnterculturalCoordination of Teachers (2012 2014))

    DTIC Science & Technology

    2016-08-01

    Programm und der Prazess der Qualifizierung a us der Perspektive der teilnehmenden Lehrkrafte und beteiligter Schul leitungen ana lysiert; (2.) wu...Folgen und Nebenwirkungen der Schulentwicklung erfassen und ana - lysieren zu kiinnen, ermiig lichen insbesondere zwei Traditionen der neueren...ver6ffentlicht wurden, die Erfassung aktue ller Medienberichte, die Auswertung der Interviews mit den Projektleiterinnen sowie die Ana lyse von

  15. Report on the 5‘th scientific meeting of the “Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie” (NEUROWIND e.V.) held in Motzen, Germany, Oct. 25th – Oct. 27th, 2013

    PubMed Central

    2013-01-01

    From october 25th - 27th 2013, the 5th NEUROWIND e.V. meeting was held in Motzen, Brandenburg, Germany. This year more than 60 doctoral students and postdocs from over 25 different groups working in German university hospitals or research institutes attended the meeting to discuss their latest findings in the fields of neuroimmunology, neurodegeneration and neurovascular research. All participants appreciated the stimulating environment in Motzen, Brandenburg, and people took the opportunity for scientific exchange, discussion about ongoing projects and already started further collaborations. Like in the previous years, the symposium was regarded as a very well organized platform to support research of young investigators in Germany. According to the major aim of NEUROWIND e.V. to support younger researchers in Germany the 3rd NEUROWIND YOUNG SCIENTIST AWARD for experimental neurology was awarded to Ruth Stassart working in the group of Klaus Armin Nave and Wolfgang Brück (MPI Göttingen and Department of Neuropathology, Göttingen Germany). The successful work was published in Nature Neuroscience entitled “A role for Swann cell-derived neuregulin-1 in remyelination”. This outstanding paper deals with the function of Schwann cell neuregulin as an endogenous factor for myelin repair. The award is endowed with 20.000 Euro sponsored by Merck Serono GmbH, Darmstadt, Germany (unrestricted educational grant). This year’s keynote lecture was given by Albert Ludolph, Head of the Department of Neurology at the University Clinic of Ulm. Dr. Ludolph highlighted the particular role of individual scientists for the development of research concepts in Alzheimer´s disease (AD) and frontotemporal dementia (FTD). PMID:24330587

  16. Fragenkatalog zur Begrundung und Beurteilung von Einfuhrungskurskonzeptionen im Rahmen der Germanistik (Question-Catalog on the Establishment and Evaluation of Introductory-Course-Conceptions in the Area of Germanic Studies)

    ERIC Educational Resources Information Center

    Linguistik und Didaktik, 1973

    1973-01-01

    From a session of the Arbeitskreis fur Hochschuldidaktik im Germanistenverband (Workshop for College Teaching in German Departments), Loccum, West Germany, July 3-6, 1972; compiled by the Initiativgruppe Studienreform Hamburg (Proposals Committee for Curriculum Reform in Hamburg). (DD)

  17. Konzeption, Entwicklung und Evaluierung eines Messsystems zur sortenreinen Klassifikation von fluoreszenzcodierten Kunststoffen im Rahmen des Kunststoff-Recyclings(Conception, development and evaluation of a measuring system for the classification of fluorescence coded plastics within the framework of plastic recycling)

    DTIC Science & Technology

    2016-06-13

    hour per response, including the time for reviewing instructions, searchi ng existing data sources , gathering a nd maintaining the data needed , a nd...designed and imp lemented that identifies polymer flakes (with a size of few millimeters) transported on a conveyor belt in rea l time based on the...found that the implemented extraction methods and classification estimators satisfy the industrial demands of a real time processing system by showing

  18. Die nuklearen Anlagen von Hanford (1943-1987) Eine Fallstudie über die Schnittstellen von Physik, Biologie und die US-amerikanische Gesellschaft zur Zeit des Kalten Krieges

    NASA Astrophysics Data System (ADS)

    Macuglia, Daniele

    Die Geschichte des Kalten Krieges eröffnet viele Möglichkeiten, sich näher mit den Schnittstellen von Physik und Biologie während des 20. Jahrhunderts zu befassen. Nicht nur das Unglück in Tschernobyl aus dem Jahr 1986, auch das Beispiel der nuklearen Anlagen in Hanford in den Vereinigten Staaten zeigt die biologischen Folgen von nuklearer Physik.

  19. Auswirkungen von okonomischem Druck auf die psychosoziale Befindlichkeit von Jugendlichen: Zur Bedeutung von Familienbeziehungen und Schulniveau (The Effect of Economic Pressure on the Psycho-Social Well-Being of Adolescents: The Importance of Family Relations and School Track).

    ERIC Educational Resources Information Center

    Butz, Petra; Boehnke, Klaus

    1997-01-01

    Presents findings on the impact of economic pressure on the well-being of adolescents in Berlin. Shows that relative losses in purchasing power are related to decreased self-esteem in problematic family climates; school level, place of residence, and relative gain in purchasing power played a greater role in xenophobia and aggressive helplessness.…

  20. Report on the 4'th scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Nov. 2'nd - Nov. 4'th, 2012.

    PubMed

    Linker, Ralf A; Meuth, Sven G; Magnus, Tim; Korn, Thomas; Kleinschnitz, Christoph

    2012-11-22

    From November 2nd - 4th 2012, the 4th NEUROWIND e.V. meeting was held in Motzen, Brandenburg, Germany. Again more than 60 participants, predominantly at the doctoral student or postdoc level, gathered to share their latest findings in the fields of neurovascular research, neurodegeneration and neuroinflammation. Like in the previous years, the symposium provided an excellent platform for scientific exchange and the presentation of innovative projects in the stimulating surroundings of the Brandenburg outback. This year's keynote lecture on the pathophysiological relevance of neuronal networks was given by Christian Gerloff, Head of the Department of Neurology at the University Clinic of Hamburg-Eppendorf. Another highlight of the meeting was the awarding of the NEUROWIND e.V. prize for young scientists working in the field of experimental neurology. The award is donated by the Merck Serono GmbH, Darmstadt, Germany and is endowed with 20.000 Euro. This year the jury decided unanimously to adjudge the award to Michael Gliem from the Department of Neurology at the University Clinic of Düsseldorf (group of Sebastian Jander), Germany, for his outstanding work on different macrophage subsets in the pathogenesis of ischemic stroke published in the Annals of Neurology in 2012.

  1. Unterricht nach dem Funkkurs Englisch. Eine Unterrichtsstunde zur 2. Sendung des Rundfunkkurses English for you 3 (Teaching with the Radio Course in English. A Teaching Hour on the 2nd Braodcast of the Radio Course "English for You, 3")

    ERIC Educational Resources Information Center

    Lemmer, Ilse

    1974-01-01

    Describes an instructional hour on the second broadcast of the radio course "English for you, 3"; prerequisites, procedure, work with the tape segments, design of the exercises. (Text is in German.) (IFS/WGA)

  2. Zur systematischen Behandlung von phrasal-prepositional verbs im Englischunterricht der Mittelund Oberstufe (On the Systematic Treatment of Phrasal-Prepositional Verbs in Teaching English at the Intermediate and Upper Levels)

    ERIC Educational Resources Information Center

    Saftien, Volker

    1975-01-01

    Proposes an intensive introductory period, attacking problems presented by these verbs, using a basic list of 60 verbs, to be learned in active and passive, and a subsequent treatment, lasting for years, integrating these verbs into the student's active use, plus acquisition of more such verbs. (Text is in German.) (IFS/WGA)

  3. Attitudes, experiences, et performance en mathematique d'etudiantes et d'etudiants de cinquieme secondeire selon leur choix scolaire. Les cahiers de recherche de GREMF. Cahier 9. (Female and Male Students' Attitudes, Experiences and Performance in Mathematics in Grade ll, According to Their Academic Choices. GREMF Research Reports. Report 9).

    ERIC Educational Resources Information Center

    Mura, Roberta; And Others

    In order to advance our understanding of the mechanisms through which women come to be underrepresented in mathematics and science, factors associated with the academic choices of students in three grade ll classes were studied. Information was gathered through questionnaires, interviews with students and with their mathematics teachers, classroom…

  4. Survey of the impact of randomised clinical trials on surgical practice in France. French Associations for Research in Surgery (AURC and ACAPEM). Association Universitaire de Recherche en Chirurgie. Association des Chirurgiens de l'Assistance Publique pour l'Evaluation Médicale.

    PubMed

    Millat, B; Fingerhut, A; Flamant, Y; Hay, J M; Fagniez, P L; Farah, A; Duron, J J; Courchevel, J M

    1999-02-01

    To evaluate the impact of randomised clinical trials (RCT) on decision-making and therapeutic policies among general and gastrointestinal surgeons in France. Telephone questionnaire. Multicentre study, France. A random sample of 152 surgeons, mean (SD) age 50 (8) years. INTERVENTIONS AND MAIN OUTCOME MEASURE: Surgeons were asked 12 questions about their knowledge of RCT and how trials were conducted; influence of RCT on their treatment policies; means of obtaining information about treatments; how they evaluated their own results; whether they were willing to take part in RCT; and personal details including age, speciality, and type of practice. Surgeons were stratified according to age and type of practice. 148 questionnaires were suitable for analysis. 83 surgeons (56%) were under 50 years old, 38 (26%) were exclusively gastrointestinal surgeons, 82 (56%) worked in private practice, and 36 (24%) worked in teaching and university hospitals. The rest undertook mixed duties. When asked to say where they obtained their knowledge about antibiotics, 91 (61%) referred to RCT; these were mainly hospital-based, gastrointestinal, and younger surgeons. Asked to name a RCT-based policy, 81 (55%) gave medical rather than operative examples. 80 (54%) had already participated in a RCT; 79 (53%) said that they were willing to participate in a RCT that included random allocation of patients (there were no statistically significant differences in answers according to speciality or type of practice, although younger surgeons answered "yes" to both questions). Specialised journals were the main source of information for 115 (78%), and surgeons read a mean of 40 issues/year. 142 (96%) read journals in French and 66 (45%) in English, but this number fell to 10 (15%) of the 65 surgeons aged 50 or more. Personal experience was considered a more important source of therapeutic knowledge by older and specialist surgeons. 109 surgeons (74%) recalled patients during the first month postoperatively to evaluate their results. French surgeons, particularly those aged 50 or over, are not well informed about the nature, conduct, and value of RCT. Most of their information is acquired through reading and attending scientific meetings and congresses. Surgeons tended to attach more importance to the fame of the author than to the conduct of the study. The overall impact of RCT was weak among the surgeons questioned.

  5. Recherche d'une politique de gestion des stocks d'eau de barrages-réservoirs en vue de soutenir les étiages. 1. Élaboration d'un modèle alterné annuel apports-déficits

    NASA Astrophysics Data System (ADS)

    Bocquillon, C.; Masson, J. M.

    1983-01-01

    Lack of water supply during periods of deficient flow affects the economic potentiality of the great river valleys which are the most developed areas in the country. Reservoir dams built in the upper stream catchments store excess flow and provide controlled release in the dry season. Capital costs of construction and the consequences of failures justify a thorough study of operating rules. The low flows and conditional variability of availability of water call for carry-over procedures (reservoir capacity is sometimes greater than the mean available water). It is not possible to predict future sequence of flows, thus the carry-over rule is a statistical decision-making tool. The flow data are only one of the very many possible sources of information. But the analysis of flow data provides us with statistical measures to generate long series of synthetic inflows associated with summer deficits. A simplification has been introduced by choosing only the values which are absolutely necessary for optimal management research: available water volumes and reserve volumes for a flow threshold. Yearly alternate periods of excess and deficiency of water are defined by the values above and below a threshold of flow discharge at a location gage named "objective point", where the reservoir effects are to be estimated. Yearly periods are described by water volumes, either inflows into reservoirs, or deficits below various thresholds of summer flow discharges. Marginal and conditional probability distributions of these volumes and the physical laws which mark their bounds and relationships were estimated on the basis of 31 years of daily flow records. The synthetic simulated series for 1000 years was compared to records of historical levels (since 1863). Extreme events such as sequences of dry years, have return periods of comparable magnitude. This synthetic series has a similar statistical character of short historical series and makes the analysis of operating rules possible.

  6. Attitude of pregnant women towards HIV testing in Abidjan, Côte d'Ivoire and Bobo-Dioulasso, Burkina Faso. DITRAME Study Group (ANRS 049 Clinical Trial). Diminution de la Transmission Mère Enfant du VIH. Agence Nationale de Recherches sur le SIDA.

    PubMed

    Cartoux, M; Msellati, P; Meda, N; Welffens-Ekra, C; Mandelbrot, L; Leroy, V; Van de Perre, P; Dabis, F

    1998-12-03

    To evaluate the attitude of pregnant women towards HIV testing in two cities of West Africa: Abidjan, Côte d'Ivoire and Bobo-Dioulasso, Burkina Faso. In the context of a clinical trial to prevent HIV vertical transmission, HIV counselling and testing was offered systematically to women attending antenatal clinics. Informed consent was obtained and test results were given anonymously. Multiple logistic regression was performed to identify factors associated with refusal for testing and failure to return for test results. A total of 9724 pregnant women were interviewed from January 1995 to September 1996. In Abidjan (n=5766) and Bobo-Dioulasso (n=3958), 78 and 92.4% of the women consented to HIV testing, respectively, and 58.4 and 81.8% of them returned for the test results disclosure, respectively. In the two sites, the counsellors themselves and high educational level of the women appeared to be related to refusal of the test, whereas last trimester gestation was associated with failure to return for test results. In Abidjan, foreigners and employees were more likely to refuse testing, and HIV-infected women were three times less likely to return for results than uninfected women. Future implementation of interventions to reduce vertical transmission of HIV that require antenatal HIV testing and counselling will have to solve issue of acceptability of HIV testing by pregnant women.

  7. The Training of Modern Language Teachers in Various Countries. Collection d'"Etudes linguistiques," No. 20. Selected papers from the Association Internationale pour la Recherche et la Diffusion des Methodes Audio-Visuelles et Structuro-Globales Seminar (5th, August 27-September 1, 1973).

    ERIC Educational Resources Information Center

    Nivette, Jos, Ed.

    Selected papers that address theoretical and practical training of the modern language teacher and language teaching experiments in various countries are presented. Some of the articles included are the following: "Les problemes de la formation linguistique et pedagogique des professeurs de francais en Afrique Subsaharienne" (The…

  8. Never conclude with a negative result, explore all possibilities before changing your hypothesis. An interview with Dr. Catherine Figarella, former Director Groupe de Recherche sur les Glandes Exocrines, Faculté de Médecine, Marseille, France; Active Member of the Board of the French Cystic Fibrosis Association: 'Vaincre la Mucoviscidose'. Interview by Martín E. Fernández-Zapico.

    PubMed

    Figarella, Catherine

    2010-01-01

    Dr. Catherine Figarella is a world expert in the isolation and characterization of human exocrine pancreatic proteins (enzymatic and non-enzymatic ones). She was a pioneer in the identification and characterization of the numerous zymogens present in pancreatic juice. In particular, her discovery of a peculiar behavior of one of the main proteolytic zymogens: human trypsinogen 1, which was more readily activated into active trypsin than human trypsinogen 2 and trypsinogens of other species led her to propose that a premature intracellular activation of this zymogen may play a role in the pathogenesis of chronic pancreatitis. She demonstrated that a similar phenomenon may occur in cystic fibrosis (CF) and has applied this knowledge of pancreatic zymogens to follow the evolution of the pancreatic disease in CF. With this brief but keen biographical article Dr. Figarella shares her life experience as an innovative medical and biochemical investigator of human exocrine pancreatic function. Copyright 2010 S. Karger AG, Basel.

  9. Human Factors Analysis of Aircrew Operational Tasks in a Fixed-Wing Search and Rescue Aircraft Cargo Compartment (Analyse des facteurs humains lies aux taches operationnelles qui sont executees par les membres d’equipage dans la soute des avions de recherche et de sauvetage)

    DTIC Science & Technology

    2011-05-01

    Techs during operational tasks was evaluated. The results were used to provide guidance based on ergonomics principals, standards in the industry, and...results indicate that the postural and loading demands were well above those accepted based on ergonomics practice and occupational limitations...placed on SAR Techs were well above the acceptable upper limits based on industry-standard ergonomics guidance. It was demonstrated using QBack

  10. Les professions langagieres a l'aube de l'an 2000: Recherches pedagogiques et linguistiques en traduction, redaction et terminologie (The Language Professions at the Dawn of the Year 2000: Pedagogical and Linguistic Research in Translation, Editing and Terminology). Publication B-217.

    ERIC Educational Resources Information Center

    Guevel, Zelie, Ed.; Clerc, Isabelle, Ed.

    Essays, all in French, address issues in language teacher and translator training. They include: "Les competences linguistiques et discursives du redacteur professionel: un ensemble a circonscrire" ("Linguistic and Discourse Competencies of the Professional Editor: A Unity To Define") (Celine Beaudet); "Les composantes d'un enseignement systemique…

  11. L'identite ethnolinguistique et les eleves 16 ans ou plus qui frequentent les ecoles secondaires de langue francaise de l'Ontario. Rapport de recherche (The Ethno-Linguistic Identity of Students Aged 16 Years or Older Attending French-Language Secondary Schools in Ontario. Research Report).

    ERIC Educational Resources Information Center

    Duquette, Georges

    The report, written in French, presents the results of a study on the ethno-linguistic identity of students aged 16 years or older attending French language secondary schools in Ontario. Goals of the questionnaire study included the following: (1) gathering demographics on students about to graduate from high school, regarding their gender,…

  12. Benefits of task-shifting HIV care to nurses in terms of health-related quality of life in patients initiating antiretroviral therapy in rural district hospitals in Cameroon [Stratall Agence Nationale de Recherche sur le SIDA (ANRS) 12110/Ensemble pour une Solidarité Thérapeutique Hospitalière en Réseau (ESTHER) substudy].

    PubMed

    Suzan-Monti, M; Blanche, J; Boyer, S; Kouanfack, C; Delaporte, E; Bonono, R-C; Carrieri, P M; Protopopescu, C; Laurent, C; Spire, B

    2015-05-01

    The World Health Organization (WHO) recommends task-shifting HIV care to nurses in low-resource settings with limited numbers of physicians. However, the effect of such task-shifting on the health-related quality of life (HRQL) of people living with HIV (PLHIV) has seldom been evaluated. We aimed to investigate the effect of task-shifting HIV care to nurses on HRQL outcomes in PLHIV initiating antiretroviral therapy (ART) in rural district hospitals in Cameroon. Outcomes in PLHIV were longitudinally collected in the 2006-2010 Stratall trial. PLHIV were followed up for 24 months by nurses and/or physicians. Six HRQL dimensions were assessed during face-to-face interviews using the WHO Quality of Life (WHOQOL)-HIV BREF scale: physical health; psychological health; independence level; social relationships; environment; and spirituality/religion/personal beliefs. The degree of task-shifting was estimated using a consultant ratio (i.e. the ratio of nurse-led to physician-led visits). The effect of task-shifting and other potential correlates on HRQL dimensions was explored using a Heckman two-stage approach based on linear mixed models to adjust for the potential bias caused by missing data in the outcomes. Of 1424 visits in 440 PLHIV (70.5% female; median age 36 years; median CD4 count 188 cells/μL at enrolment), 423 (29.7%) were task-shifted to nurses. After multiple adjustment, task-shifting was associated with higher HRQL level for four dimensions: physical health [coefficient 0.7; 95% confidence interval (CI) 0.1-1.2; P = 0.01], psychological health (coefficient 0.5; 95% CI 0.0-1.0; P = 0.05), independence level (coefficient 0.6; 95% CI 0.1-1.1; P = 0.01) and environment (coefficient 0.6; 95% CI 0.1-1.0; P = 0.02). Task-shifting HIV care to nurses benefits the HRQL of PLHIV. Together with the previously demonstrated comparable clinical effectiveness of physician-based and nurse-based models of HIV care, our results support the WHO recommendation for task-shifting. © 2015 British HIV Association.

  13. The Training of Modern Language Teachers in Various Countries. Collection d'"Etudes linguistiques," No. 20. Selected papers from the Association Internationale pour la Recherche et la Diffusion des Methodes Audio-Visuelles et Structuro-Globales Seminar (5th, August 27-September 1, 1973).

    ERIC Educational Resources Information Center

    Nivette, Jos, Ed.

    Selected papers that address theoretical and practical training of the modern language teacher and language teaching experiments in various countries are presented. Some of the articles included are the following: "Les problemes de la formation linguistique et pedagogique des professeurs de francais en Afrique Subsaharienne" (The…

  14. Factors associated with mortality in human immunodeficiency virus type 1-infected adults initiating protease inhibitor-containing therapy: role of education level and of early transaminase level elevation (APROCO-ANRS EP11 study). The Antiprotéases Cohorte Agence Nationale de Recherches sur le SIDA EP 11 study.

    PubMed

    Lewden, Charlotte; Raffi, François; Cuzin, Lise; Cailleton, Valérie; Vildé, Jean-Louis; Chêne, Geneviève; Allavena, Clotilde; Salamon, Roger; Leport, Catherine

    2002-09-01

    This study attempted to identify factors associated with mortality among human immunodeficiency virus (HIV)-infected adults starting a protease inhibitor (PI)-containing therapy. Among 1155 patients consecutively enrolled in the APROCO study between May 1997 and June 1998, clinical characteristics were as follows: median age, 36 years; median baseline CD4 cell count, 288 cells/mm(3); and median baseline plasma HIV RNA load, 4.4 log(10) copies/mL. After a median follow-up of 27 months, 48 deaths had occurred, of which 44% were related to acquired immune deficiency syndrome. The mortality rate was 2.9% at 12 months. When both data at baseline and data at 4 months after the start of PI therapy were considered, factors independently associated with mortality were (Cox model) low baseline plasma creatinine level, low school education level, low CD4 cell count at 4 months, low hemoglobin level, and elevated hepatic transaminase levels. Thus, social context plus clinical and biologic data, including the 4-month response to treatment, must be considered in treatment of HIV-infected patients.

  15. La recherche de la surexpression de la protéine et l'amplification du gène HER2 dans le cancer de l'estomac par immunohistochimie et Hybridation in Situ: expérience du CHU HASSAN II de Fès

    PubMed Central

    El Fatemi, Hinde; Hammas, Nawal; Idrissi, Karima; Mellas, Nawfel; Bennani, Amal; Amarti, Afaf; Cayre, Anne; Penault-llorca, Frederique; Mesbahi, Omar

    2012-01-01

    La surexpression de l'Her2 a été détectée dans plusieurs cancers et a été particulièrement étudiée dans le cancer du sein. Elle est décrite dans 10 à 30% des adénocarcinomes gastriques. Un statut HER2 positif est un facteur de mauvais pronostic et un facteur prédictif de la réponse à l'herceptine (trastuzumab). Cet article présente les résultats d'une étude préliminaire portant sur 31 cas de tumeurs gastriques, et dont le but est d’évaluer la surexpression de l’ HER2 dans les adénocarcinomes gastriques avancés tout en comparant nos résultats avec ceux de la littérature. Le taux des cas surexprimant l'Her2 dans notre étude (35.5%) est proche de celui noté par Aoyaji et al (34%), mais il est supérieur à celui noté dans la plupart des séries de la littérature notamment une vaste étude baptisée TOGA. La poursuite de cette étude par un échantillon plus large est nécessaire afin de mieux comprendre les particularités de ce cancer dans notre contexte. PMID:23397021

  16. Search for the Higgs Boson and for Anomalous Quartic Gauge Boson Couplings in the WW Channel with Dielectron Events with the D0 Experiment at the Tevatron; Recherche du boson de Higgs et de couplages de jauge quartiques anormaux dans le canal WW en électrons dans l'expérience D0 au Tevatron

    SciTech Connect

    Chapon, Emilien

    2013-01-01

    Le paysage de la physique des particules a subi des changements majeurs entre le début de cette thèse, en septembre 2010, et sa n en juin 2013. On peut notamment qualier l'année 2012 de date-clé dans l'histoire de la physique des particules. En 2012, une nouvelle particule a été découverte au LHC [1, 2], dont la majeure partie de la communauté s'accorde aujourd'hui à dire qu'il s'agit très probablement du boson de Higgs. Cet événement est intervenu peu après une sorte de passage de relais entre le Tevatron, arrêté le 30 septembre 2011, et le LHC, dont les toutes premières collisions sont intervenues le 23 novembre 2009.

  17. Finding the Higgs boson of the standard model in the channel ZH → e+e-b$\\bar{b}$ with the D0 detector at the Tevatron; Recherche du boson de Higgs du nideke standard dans le canal ZH → e+e-b$\\bar{b}$ avec le detecteur DØ aupres du Tevatron

    SciTech Connect

    Calpas, Betty Constante

    2010-06-11

    The organization of this thesis consists of three main ideas: the first presents the theoretical framework and experimental, as well as objects used in the analysis and the second relates to the various work tasks of service that I performed on the calorimeter, and the third is the search for the Higgs boson in the channel ZH → e+e-b$\\bar{b}$. Thus, this thesis has the following structure: Chapter 1 is an introduction to the standard model of particle physics and the Higgs mechanism; Chapter 2 is an overview of the complex and the acceleration of the Tevatron at Fermilab DØ detector; Chapter 3 is an introduction to physical objects used in this thesis; Chapter 4 presents the study made on correcting the energy measured in the calorimeter; Chapter 5 describes the study of certification of electrons in the calorimeter; Chapter 6 describes the study of certification of electrons in the intercryostat region of calorimeter; Chapter 7 Detailed analysis on the search for Higgs production in the channel ZH → e+e-b$\\bar{b}$; and Chapter 8 presents the final results of the calculations of upper limits to the production cross section of the Higgs boson on a range of low masses.

  18. A Helpful Framework for the Organization of the Homecare

    DTIC Science & Technology

    2007-11-02

    Beuscart1 1 Centre d’Etude et de Recherches en Informatique Médicale – Université de Lille2 – Faculté de Médecine – LILLE France 2 LAMIH- PERCOTEC, UVHC, Le...Recherches en Informatique Medicale Universite de Lille2- Faculte de Medecine- LILLE France Performing Organization Report Number Sponsoring/Monitoring Agency

  19. Examination of Rotating Spoke Instability in a Cross-Field Discharge

    DTIC Science & Technology

    2013-07-08

    Vaudolon ** R. Schneider, K. Matyash *** Y. Raitses, A. Diallo, Y. Shi * CTRE Nat De La Recherche Scientifique , CNRS MOY800 CTRE Poitou...Charente, 3, Ave Recherche Scientifique , Orleans 45000 France ** Ernst-Moritz-Arndt Universitat Greifswald, Greifswald, Germany *** Princeton Plasmas...Air Force Research Laboratory Air Force Office of Scientific Research European Office of Aerospace Research and Development Unit 4515

  20. The Investigation and Production of Titanium-Tantalum Junctions Diffusion Bonded at High Temperature (855C to 920C): the Influence of Temperature, Time Pressure and Roughness on the Mechanical Properties, and the Optimisation of the Bonded Conditions

    DTIC Science & Technology

    1990-01-01

    the assemblies fractured in the tantalum at 380 MPa. Acknowledgements We wish to thank the TA (Technologie Appliqude) department of the Commissariat a...1984) 8 M. Hourcade Compte rendu annuel d’un recherche financfe par le Minista re de La Recherche et de Z’Industrie. (Annual report of research

  1. Certainty Equivalence and Inequivalence for Prices

    DTIC Science & Technology

    1988-12-01

    risque’, Econometrie (Paris: Editions du Centre National de la Recherche Scientifique) Pp. 81-109. Arrow, K.J. (1953) ’Role des valeurs boursieres pour ]a...repartition la meilleure des risques’, Econometrie (Paris: Editions du Centre National de La Recherche Scientifique) Pp. 41-47. Bernoulli, 0. (1738

  2. Cumulative Viral Load and Virologic Decay Patterns After Antiretroviral Therapy in HIV-Infected Subjects Influence CD4 Recovery and AIDS

    DTIC Science & Technology

    2011-05-20

    Cohorte Agence Nationale de Recherches sur le SIDA EP 11 study. J Infect Dis 186: 710–714. 8. Hermankova M, Ray SC, Ruff C, Powell-Davis M, Ingersoll R, et...malignancy in HIV-infected patients during the combination antiretroviral therapy era: Agence Nationale de Recherche sur le Sida (ANRS) CO3 Aquitaine

  3. Nicolaus Copernicus (1473 - 1543) - Revolutionär wider Willen.

    NASA Astrophysics Data System (ADS)

    Wolfschmidt, G.

    Begleitbuch zur Copernicus-Ausstellung vom 22. Juli bis 19. Oktober 1994 im Zeiss-Großplanetarium in Berlin. Contents: 1. Der Weg zum modernen Weltbild. 2. Antikes und mittelalterliches Weltbild. 3. Nicolaus Copernicus (1473 - 1543). 4. Wirkungsgeschichte des Copernicus. 5. Katalog zur Copernicus-Ausstellung. Introduction: Copernicus, Mythos und Moderne (J. Teichmann).

  4. Physik gestern und heute: Fragwürdiges beim Millikan-Versuch

    NASA Astrophysics Data System (ADS)

    Heering, Peter

    2006-09-01

    Robert A. Millikan erhielt 1923 als erster amerikanischer Physiker den Nobelpreis für Physik. Geehrt wurde er für seine Präzisionsmessungen zum Photoeffekt und zur experimentellen Bestimmung der elektrischen Elementarladung. Millikans Experimente zur Elementarladung sind auch heute noch ein Standardthema im schulischen Physikunterricht, gleichzeitig werfen sie aber eine Reihe von wissenschaftstheoretischen und ethisch relevanten Fragen auf.

  5. What are the Ethical Problems Raised by the Increase of Cognitive Capabilities in the Defence Structure: The French Legal Structure, the Ethical Position of the French Military Health Service

    DTIC Science & Technology

    2009-10-01

    Recherches du Service de Santé des Armées Département des facteurs Humains 24, avenue des maquis du Grésivaudan BP 87, 38702 La Tronche cedex France...UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Institut de recherches biomédicales-Centre de Recherches du Service de Santé des Armées...developing his muscles for physical resistance indispensable for practicing his sport . There is a freedom of action more advanced than functional

  6. Francais langue etrangere: l'enseignement de l'orthographe elementaire aux adolescents mal scolarises issus de milieux socio-culturels defavorises. Quelques notes sur une recherche (French as a Foreign Language: The Teaching of Elementary Spelling to Adolescents Who Were Slow Learners and Who Had Come from Disadvantaged Milieux. Some Research Notes). Acts of the Colloquium of the Swiss Interuniversity Commission for Applied Linguistics. CILA Bulletin, No. 25.

    ERIC Educational Resources Information Center

    Rey-von-Allmen, Micheline

    The reflections in this paper represent part of a study of disadvantaged 13 to 15 year-old children of immigrants in Switzerland. This section deals with the process of learning spelling. In order to observe the students' learning, the same dictation was given four times during the school year. The results were studied intuitively and…

  7. Safety and immunogenicity of a live recombinant canarypox virus expressing HIV type 1 gp120 MN MN tm/gag/protease LAI (ALVAC-HIV, vCP205) followed by a p24E-V3 MN synthetic peptide (CLTB-36) administered in healthy volunteers at low risk for HIV infection. AGIS Group and L'Agence Nationale de Recherches sur Le Sida.

    PubMed

    Salmon-Céron, D; Excler, J L; Finkielsztejn, L; Autran, B; Gluckman, J C; Sicard, D; Matthews, T J; Meignier, B; Valentin, C; El Habib, R; Blondeau, C; Raux, M; Moog, C; Tartaglia, J; Chong, P; Klein, M; Milcamps, B; Heshmati, F; Plotkin, S

    1999-05-01

    A live recombinant canarypox vector expressing HIV-1 gpl20 MN tm/gag/protease LAI (ALVAC-HIV, vCP205) alone or boosted by a p24E-V3 MN synthetic peptide (CLTB-36) was tested in healthy volunteers at low risk for HIV infection for their safety and immunogenicity. Both antigens were well tolerated. ALVAC-HIV (vCP205) induced low levels of neutralizing antibodies against HIV-1 MN in 33% of the volunteers. None of them had detectable neutralizing antibodies against a nonsyncytium-inducing HIV-1 clade B primary isolate (Bx08). After the fourth injection of vCP205, CTL activity was detected in 33% of the volunteers and was directed against Env, Gag, and Pol. This activity was mediated by both CD4+ and CD8+ lymphocytes. On the other hand, the CLTB-36 peptide was poorly immunogenic and induced no neutralizing antibodies or CTLs. Although the ALVAC-HIV (vCP205) and CLTB-36 prime-boost regimen was not optimal, further studies with ALVAC-HIV (vCP205) are warranted because of its clear induction of a cellular immune response and utility as a priming agent for other subunit antigens such as envelope glycoproteins, pseudoparticles, or new peptides.

  8. Linking Research to Practice: A Canadian Forum. Proceedings of the Canadian Child Care Federation and the Association of Canadian Community Colleges (Ottawa, Ontario, October 25-27, 1998) = De la recherche a la pratique: Un forum Canadien. Actes du forum la federation canadienne des services de garde a l'enfance et l'association des colleges communautaires du Canada (Ottawa, Ontario, de 25 au 27 octobre 1998).

    ERIC Educational Resources Information Center

    Whitehead, Judith, Ed.; Huot, Gaetane, Ed.

    This report compiles the proceedings from a national forum of the Canadian Child Care Federation held in October 1998, which provided an opportunity for early childhood educators, practitioners, and researchers to share knowledge, learn from each other, and network with colleagues. The agenda included 3 keynote speeches and over 35 workshops on…

  9. Recherche du boson de Higgs dans l'état final dimuonique et étude de l'asymétrie de production de la paire top antitop avec l'expérience DO auprès du Tevatron; Higgs boson search in the dimuonique final state and study of the top pair antitop production asymmetry with the DO experiment at the Tevatron.

    SciTech Connect

    Fauré, Alexandre

    2014-06-03

    Two high energy particle physics analyses are presented in this PhD report using events with two leptons oppositely charged and with missing transverse energy. These events are selected using 9.7 fb-1 of total pp collisions data collected with the DØ detector at the TeVatron at √s=1.96 TeV.The first analysis is the research of the Higgs boson decaying in the H→WW→μνμν channel. No significant excess above the background prediction is observed.Upper limits on Higgs boson production cross-section are computed in the standard model framework but also in the 4th generation of fermions and in the fermiophobic coupling to Higgs boson hypotheses. In order to validate the research methodology, the W boson pair production cross-section is measured.The second analysis is the measurement of the forward-backward asymmetry of the tt pair production. This is the first measurement in the dileptonic channel at DØ experiment. In this context, a new tt pair kinematic reconstruction is used (matrix element method) to give a raw measurement of the forward-backward asymmetry. Thanks to a dedicated calibration method, we give a final measurement of AFB=18.0 ± 6.0 (stat) ± 3.3 (syst).

  10. Analyse conversationnelle et representations sociales: Unite et diversite de L'image du bilinguisme (Conversational Analysis and Social Representations: Unity and Diversity in the Image of Bilingualism).

    ERIC Educational Resources Information Center

    Py, Bernard, Ed.

    2000-01-01

    Articles in this issue include the following: "Representations sociales et discours. Questions epistemologiques et methodologiques" (Social Representations and Discourse. Questions of Epistemology and Methodology); "Aspects theoretiques et methodologiques de la recherche sur le traitement discursif des representations sociales"…

  11. Analyse conversationnelle et representations sociales: Unite et diversite de L'image du bilinguisme (Conversational Analysis and Social Representations: Unity and Diversity in the Image of Bilingualism).

    ERIC Educational Resources Information Center

    Py, Bernard, Ed.

    2000-01-01

    Articles in this issue include the following: "Representations sociales et discours. Questions epistemologiques et methodologiques" (Social Representations and Discourse. Questions of Epistemology and Methodology); "Aspects theoretiques et methodologiques de la recherche sur le traitement discursif des representations sociales"…

  12. Werner Heisenberg zum 100. Geburtstag: Pionier der Quantenmechanik

    NASA Astrophysics Data System (ADS)

    Jacobi, Manfred

    2001-11-01

    Werner Heisenberg war eine der prägendsten Gestalten der Physik des 20. Jahrhunderts. Zu seinen wichtigsten Verdiensten gehören die Grundlegung der Quantenmechanik, die Formulierung der Unschärferelationen sowie die Beteiligung an der Ausarbeitung der Kopenhagener Deutung der Quantenmechanik. Darüber hinaus lieferte er Arbeiten von fundamentalem Charakter zur Theorie des Atomkerns, zur kosmischen Strahlung und zur Quantenfeldtheorie. Während des Krieges war er an den Arbeiten des Uranvereins beteiligt, der die Möglichkeit einer Entwicklung von Kernwaffen untersuchte, jedoch über Vorarbeiten zur Reaktorphysik nicht hinauskam. Wegen dieser Tätigkeit wurde er bei Kriegsende für einige Monate in England interniert. Nach seiner Rückkehr widmete er sich vor allem dem Aufbau der Physik in Deutschland, die während der NS-Zeit nahezu ihrer gesamten Substanz beraubt worden war.

  13. Measurement of Venous Blood Flow in the Lower Limbs: Prevention of Deep Vein Thrombosis during Prolonged Sitting

    DTIC Science & Technology

    2004-06-01

    are recommended along with leg exercises during a sitting posture. 5. Acknowledgments This study was supported by Koito Industries , Ltd, Japan...Stuttgart, Germany: Ergonomia . Virchow, R. (1954). Gesammelte Abhandlungen zur Wissenscaftlischen Medizin.. Meidinger, Frankfurt.

  14. Unfälle mit Pkw

    NASA Astrophysics Data System (ADS)

    Burg, Heinz

    Der Verkehrsunfall ereignete sich innerorts auf einer Kreuzung mit rechts vor links Regelung. Es galt dort die allgemeine Geschwindigkeitsbegrenzung auf 50 km/h. Zur Unfallzeit war es hell und trocken. Die Fahrbahn hatte eine Schwarzdecke.

  15. LA TRANSPLANTATION HÉPATIQUE ORTHOTOPIQUE À L’UNIVERSITÉ DU COLORADO

    PubMed Central

    Corman, J.; Starzl, T. E.

    2010-01-01

    Ce travail a été réalisé grâce aux fonds de recherche de la Veterans Administration, aux fonds RR-00051 et RR-00069 du programme des centres de recherche clinique générale de la Division of Research Resources, National Institutes of Health, et aux fonds AI-10176-01, AI-AM-08898, et AM-07772. PMID:21572894

  16. Laser Annealing of Ion Implanted Semiconductors.

    DTIC Science & Technology

    1984-07-01

    I’Universiti Pierre et Marie Curie associi au Centre National de la Recherche Scientifique, 4 Place Jussieu, F- 75230 Paris Cedex 05, France (Received 15...Laboratoire de Physique des Solides, associi au Centre National de la Recherche Scientifique, Universite Pierre et Marie Curie, Tour 13, Deuxiime Etage, 4 Place...White and Peercy ( Academic Press), 1980, p. 156 12 J.M. Liu, R. Yen, H. Kurz and N. Bloembergen :Appl. Phys. Lett. 39, 755 (1981) 13 G.A. Rozgonyi

  17. Toward Ultrasonic Tunable Ultra-Damping Metamaterials

    DTIC Science & Technology

    2014-03-06

    O. Poncelet, C. Aristegui, J. Leng, B. Mascaro, K. Zimny CTRE NAT DE LA RECHERCHE SCIENTIFIQUE 1, ESPLANADE DES ARTS ET METIERS TALENCE...Force Research Laboratory Air Force Office of Scientific Research European Office of Aerospace Research and Development Unit 4515, APO AE 09421...ADDRESS(ES) CTRE NAT DE LA RECHERCHE SCIENTIFIQUE 1, ESPLANADE DES ARTS ET METIERS TALENCE, 33400 FRANCE 8. PERFORMING ORGANIZATION REPORT

  18. Acoustic Metamaterials Through a Microfluidic, Bottom-up Approach: Toward Highly Attenuating, Negative Effective Density Materials

    DTIC Science & Technology

    2012-10-01

    CTRE NAT DE LA RECHERCHE SCIENTIFIQUE (CNRS) 1, Esplanade Des Arts et Metiers Talence 33400 France N/A European Office of Aerospace Research and...RECHERCHE SCIENTIFIQUE (CNRS) 1, Esplanade Des Arts et Metiers Talence 33400 France EOARD SPC 11-4006 Report Date: October 2012 Final Report...for 26 April 2011 to 26 September 2012 Air Force Research Laboratory Air Force Office of Scientific Research European Office of

  19. DRDC Technical Stream Integrated Capabilities and Vision

    DTIC Science & Technology

    2011-09-01

    organisationnelle et de la Philosophie du partenariat professionnel de Recherche et développement pour la défense Canada – Toronto, le Réseau technique (RT...Grâce à la mise en œuvre du Programme d’harmonisation organisationnelle (PHO) et de la Philosophie du partenariat professionnel (PPP) de Recherche et...technologists and others, as well as variable management of performance and limited developmental opportunities. Organizationally, DRDC Toronto was impacted

  20. DRDC Toronto Technical Stream Integrated Capabilities and Vision

    DTIC Science & Technology

    2011-09-01

    organisationnelle et de la Philosophie du partenariat professionnel de Recherche et développement pour la défense Canada – Toronto, le Réseau technique (RT...mise en œuvre du Programme d’harmonisation organisationnelle (PHO) et de la Philosophie du partenariat professionnel (PPP) de Recherche et...variable management of performance and limited developmental opportunities. Organizationally, DRDC Toronto was impacted, as the diverse and highly

  1. Control of Large-Scale Civil Conflicts in Democratic Nigeria

    DTIC Science & Technology

    2007-11-02

    country. On the 7 other hand, the federal government handles the lucrative taxes from imports, customs, excises , business and mining. The states generate...Adisa (Ibadan, Nigeria: Institut Francais de Recherche en Afrique , 1994), 115. 8 Isaac Olawale Albert, Introduction to Third-Party Intervention in...Institut Francais de Recherche en Afrique , 2001),3. 10 Isaac Olawale Albert, Introduction to Third-Party Intervention in Community Conflicts (Ibadan

  2. Micro-Doppler Radar Signatures for Itelligent Target Recognition

    DTIC Science & Technology

    2004-09-01

    es. En tant qu’outil d’identification et de reconnaissance, l’effet m-D semble prometteur pour les syst~mes op ~ rationnels susceptibles d’am~liorer...Defence Research and Recherche et developpement Development Canada pour la defense Canada DEFENCE DE7 DEFENS . Micro-Doppler radar signatures for... recherche permettant d’atteindre les objectifs techniques d6sir6s. ii DRDC Ottawa TM 2004-170 Executive summary Mechanical vibrations or rotations of

  3. Non-Linear Aeroelastic Analyses and Testing,

    DTIC Science & Technology

    1981-07-01

    et de Recherches Adrospatiales (ONERA) 92320 - Chatillon (France) REbUME On prdsente deux mithodes qui permettent de traiter les rdponses harmoniques...traitement par le calcul qui revient A rechercher , de fagon explicite ou non, Ia combinaison dleaaais non approprids simulant au mieux un easai...limitd de points, voire mA-ne en un saul point. Le lissage des fonctions de transfert par des fractions rationnelles , devanu classique depuis quelquea

  4. Frontalkollisionsschutzsysteme

    NASA Astrophysics Data System (ADS)

    Winner, Hermann

    Unfälle im Längsverkehr zählen zur größten Gruppe der Unfallarten und zur zweitgrößten der Unfälle mit Getöteten und Schwerverletzten. Daher besitzen Systeme zum Schutz gegen diese Unfallart ein sehr hohes Potenzial (s. Kap. 3). Auf welche Weise Gegenmaßnahmen abgeleitet werden, zeigt Bild 33-1.

  5. Verfügbarkeit von Montagesystemen

    NASA Astrophysics Data System (ADS)

    Wiendahl, Hans-Peter; Hegenscheidt, Matthias

    Im Vergleich zur Teileherstellung wird bei einer Montageanlage eine ungleich größere Anzahl verschiedener Teile in verketteten Stationen mit Taktzeiten im Sekundenbereich verarbeitet. Weiterhin sind viele unterschiedliche Füge- and Handhabungsfunktionen zur Montage and Prüfung der teilweise empfindlichen Teile erforderlich. Und schließlich erfordert die Verkettung and Speicherung der Teile and Zwischenprodukte umfangreiche Transport- and Speichereinrichtungen. In der Praxis treten daher vergleichsweise oft Unterbrechungen unterschiedlicher Dauer auf.

  6. 25 Jahre - Institut fuer Geodaesie, Teil 1: Wissenschaftliche Beitraege und Berichte (25 Years - Institute of Geodesy, Part 1: Scientific Contributions and Reports)

    DTIC Science & Technology

    2000-01-01

    des Dispersionswinkels zur Bestimmung der Refraktion. AVN 100, S. 51-62, 1993 HAMMING, R., W.: Digitale Filter. VCH-Verlag, Weinheim 1987 HAMPEL, F...KRONMOLLER, H.: Digitale Signalverarbeitung. Springer-Verlag, Berlin 1991 KUHLMANN, H.: Ein Beitrag zur Oberwachung von Briickenbauwerken mit...1987), das Europdische Referenzsystem - EUREF (SEEGER/ALTINER/ENGELHARDT/FRANKE/HABRICH/SCHLC- TER 1998) und das Sistema di Referencia del America del

  7. Leistungsverzeichnis

    NASA Astrophysics Data System (ADS)

    Bölke, Klaus-Peter

    Grundvoraussetzung eines jeden Dienstleistungsauftrages ist eine Ausschreibung, die öffentlich oder auch beschränkt erfolgen kann. Hierfür sind vom Auftraggeber entsprechende Ausschreibungstexte herauszugeben. Diese Ausschreibungstexte müssen sich aus den Vorbemerkungen, die die allgemeinen Erläuterungen zum Leistungsumfang, den Leistungen des Auftraggebers, den Anforderungen zur personellen, gerätetechnischen und fachlichen Kompetenz eines Auftragnehmers sowie den Anforderungen zur Durchführung der zu leistenden Arbeit und den allgemeinen Vertragsbedingungen beinhalten,

  8. Infection control: Knowledge and compliance among Saudi undergraduate dental students.

    PubMed

    Al-Maweri, Sadeq Ali; Tarakji, Bassel; Shugaa-Addin, Bassam; Al-Shamiri, Hashem M; Alaizari, Nader Ahmed; AlMasri, Ousamah

    2015-01-01

    Zielsetzung: In der Studie sollten die Kenntnisse, die Einstellung und die praktische Umsetzung infektionspräventiver Maßnahmen bei Studenten der Zahnmedizin analysiert werden.Methode: In einer Querschnittsstudie wurde ein selbst zu beantwortender Fragebogen zur Erfassung des Impfstatus, der Kenntnisse und der Einstellung zur Infektionsprävention an 600 Studenten im 4., 5. und 6. Ausbildungsjahr des Al-Farabi College für Dentistry und Nursing, Riyadh, Saudi Arabia, verschickt. Die Daten wurden mittels SPSS analysiert. Das Signifikanzniveau wurde mit p<0,05 festgelegt.Ergebnisse: Die Responserate betrug 85% (512 von 600). Während die Mehrzahl der Studenten (90%) gegen Hepatitis B geimpft war, war nur bei 37,4% anti-HBs bestimmt worden. 98,8% bzw. 90,8% trugen stets Schutzhandschuhe bzw. Mund-Nasen-Schutz bei der zahnärztlichen Behandlung, während das Tragen einer Schutzbrille nur in 29,2% angegeben wurde. Ein signifikant höherer Anteil der Studenten zeigte im 6. Ausbildungsjahr eine positive Einstellung zur Behandlung von Patienten mit Infektionskrankheiten im Vergleich zum 4. und 5. Ausbildungsjahr. Etwa ein Drittel der Studenten gab an, dass sich ein oder mehrere arbeitsbedingte Verletzungen bei der Patientenbehandlung ereignet hatten.Schlussfolgerung: Obwohl die Studenten ein solides Wissen und eine gute Einstellung zur Infektionsprävention hatten, war die Compliance zur praktischen Umsetzung gering. Die Ergebnisse unterstreichen die Notwendigkeit der kontinuierlichen Erziehung Saudischer Zahnmedizinstudenten zur Infektionsprävention.

  9. Beyond the center and the edge - a historical investigation about the rise and development of the Copernican and the Cosmological Principle; (German Title: Jenseits von Zentrum und Rand - Eine wissenschaftshistorische Untersuchung zur Entstehung und Entwicklung des copernicanischen und des kosmologischen Prinzips)

    NASA Astrophysics Data System (ADS)

    Jung, Tobias

    The Copernican Principle and the Cosmological Principle are generally used as a starting point in modern relativistic cosmology. Unfortunately, both principles are often mixed up or even identified. Nonetheless, it can be shown that they make different claims. From a historical point of view there are two different lines of development which lead to the statement of each principle. Here we follow the most important steps of these lines of development beginning from Ptolemy's cosmology. In 1952, Bondi summarised a discovery which had been made on different scales over and over again: that the astronomical system we are part of is not privileged neither with respect to its position within the universe nor with respect to its size. He gave the name Copernican Principle to this discovery. The Cosmological Principle was in use as a working hypothesis stating that the universe is homogeneous and isotropic on large scales nearly two decades before its name was coined by Milne in 1935.

  10. Allgemeine Sprachfaehigkeit und Fremdsprachenerwerb. Zur Struktur von Leistungsdimensionen und linguistischer Kompetenz des Fremdsprachenlerners (General Language Ability and Foreign Language Acquisition. On the Structure of Performance Dimensions and the Linguistic Competence of the Foreign Language Learner). Diskussions beitraege aus dem Institute fuer Bildungsforschung, No. 1.

    ERIC Educational Resources Information Center

    Sang, Fritz; Vollmer, Helmut J.

    This study investigates the theoretical plausibility and empirical validity of the assumption that all performance in a foreign language can be traced back to a single factor, the general language ability factor. The theoretical background of this hypothesis is reviewed in detail. The concept of a unitary linguistic competence, interpreted as an…

  11. Networking as a Seismograph for Social Development. A Contribution to the Function Expansion of Networks Using the Example of Health Promotion of the Socially Disadvantaged (Netzwerkbildung als Seismograph gesellschaftlicher Entwicklungen: Ein Beitrag zur Funktionserweiterung von Netzwerken am Beispiel der Gesundheitsfoerderung von sozial Benachteiligten)

    DTIC Science & Technology

    2008-03-01

    vollzieht sich in den letzten Jahren Ober eine Vielzahl von Netzwerken, uber die sich unterschiedlichste Akteure miteinander verknQ~pft haben. In...indirekt, politische 2 Akteure zu adressieren und bisherige Handlungsdefizite der Gesundheitsf6rderung bei sozial Benachteiligten auch uber neue...klassischen Sinne der Korporatismusanalyse impliziert, sondern gar eine Form der Einwandvorwegnahme darsteilt. Auf der Grundlage der durch die bislang uber

  12. Aktuelle Regelungen zur Leistungsbeurteilung und zu Zeugnissen an Deutschen Sekundarschulen. Eine Vergleichende Studie aller Bundeslander--Darstellung und Diskussion Wesentlicher Ergebnisse (Recent Regulations for the Assessment of Achievement and for Grading at German Secondary Schools. A Comparative Study among all Federal Laender--Presentation and Discussions of Important Results.

    ERIC Educational Resources Information Center

    Bohl, Thorsten

    2003-01-01

    Discusses a comparative study of regulations for assessment of achievement and grading in German secondary schools. Results reveal schools provide alternatives to traditional grading and take into account interdisciplinary or special learning achievements and social behavior. Summarizes major results. Discusses problems in the basic conception and…

  13. Willkommen, Mr. Chance: Methodologische Betrachtungen zur Gute empirischer Forschung in der Padagogik, diskutiert vor allem an der neueren Untersuchung uber Gewalt von Heitmeyer u.a. (1995) = Welcome, Mr. Chance: Methodological Considerations Concerning the Quality of Empirical Research in Educational Science Based on a Recent Study on Violence Published by Heitmeyer et al. (1995).

    ERIC Educational Resources Information Center

    Wellenreuther, Martin

    1997-01-01

    Argues that the usefulness of strictly quantitative research is still questioned in educational studies, primarily due to deficiencies in methodological training. Uses a critique of a recent study by Heitmeyer et al. (1995) to illustrate the requirements of "good" empirical research. Considers the problems of hypothesis testing in field research.…

  14. Gelingende Integration? Anmerkungen zur Studie von D. Katzenbach u.a. uber den Hamburger Schulversuch "Integrative Grundschule" in ZfPad. 45 (1999), S. 567-590 (Successful Integration? Remarks on the Study by D. Katzenbach et al. on the Hamburg School Experiment "Integrative Elementary School" in ZfPad. 45 (1999), S. 567-590).

    ERIC Educational Resources Information Center

    Roeder, Peter Martin

    1999-01-01

    Critiques two normative premises that guide the researchers' interpretation of results from the Hamburg School Experiment, an empirical study that focused on mainstreaming elementary students diagnosed as needing special education: (1) integrating these children in normal classrooms is legitimated; and (2) social integration should not preclude…

  15. Gelingende Integration? Anmerkungen zur Studie von D. Katzenbach u.a. uber den Hamburger Schulversuch "Integrative Grundschule" in ZfPad. 45 (1999), S. 567-590 (Successful Integration? Remarks on the Study by D. Katzenbach et al. on the Hamburg School Experiment "Integrative Elementary School" in ZfPad. 45 (1999), S. 567-590).

    ERIC Educational Resources Information Center

    Roeder, Peter Martin

    1999-01-01

    Critiques two normative premises that guide the researchers' interpretation of results from the Hamburg School Experiment, an empirical study that focused on mainstreaming elementary students diagnosed as needing special education: (1) integrating these children in normal classrooms is legitimated; and (2) social integration should not preclude…

  16. Ueber Bild und Rolle zum Sprachhandeln. Ueberlegungen und praktische Beispiele zur Arbeit mit Rollenspiel und Bildergeschichte im Deutschunterricht mit auslaendischen Studenten (On Picture and Role in Language-in-Action. Considerations and Practical Examples of Role-Playing and Picture Stories in Teaching German to Foreign Learners).

    ERIC Educational Resources Information Center

    Loeffler, Renate

    1979-01-01

    Describes work at an American college with students who are receiving an introduction to colloquial German. Role-playing and picture stories prove useful in learning, in both productive and receptive aspects. Describing a picture on three levels--factual, psychological and contemplative--is shown to be very useful. (IFS/WGA)

  17. lndividuelle Zielvereinbarungen im Offentlichen Dienst in Deutschland Empirische Analysen zur Wirkung von Zielvereinbarungen auf die Arbeitsleistung kommunaler Beschaftigter (Individual Target Agreements in the Public Service in Germany-Empirical Analyzes of the Effect of Target Agreements on the Work Performance of Municipal Employees)

    DTIC Science & Technology

    2015-11-30

    effect of target a!ITeements on the work performance of municipal employees ) 6 . AUTHOR(S) Stefan Reemts 7 . PERFORMING ORGANIZATION NAME(S) AND...Conceptualization of the target specificity; Conceptualization of employee participation; Conceptuali zation of the target binding; Conceptualization of...fficulties; Operationalization of target specificity; Operationalization of employee participation; Operationalization of target binding

  18. Allgemeine Sprachfaehigkeit und Fremdsprachenerwerb. Zur Struktur von Leistungsdimensionen und linguistischer Kompetenz des Fremdsprachenlerners (General Language Ability and Foreign Language Acquisition. On the Structure of Performance Dimensions and the Linguistic Competence of the Foreign Language Learner). Diskussions beitraege aus dem Institute fuer Bildungsforschung, No. 1.

    ERIC Educational Resources Information Center

    Sang, Fritz; Vollmer, Helmut J.

    This study investigates the theoretical plausibility and empirical validity of the assumption that all performance in a foreign language can be traced back to a single factor, the general language ability factor. The theoretical background of this hypothesis is reviewed in detail. The concept of a unitary linguistic competence, interpreted as an…

  19. Fostering interest in research: evaluation of an introductory research seminar at hospitals in rural Rwanda.

    PubMed

    Iribagiza, M K; Manikuzwe, A; Aquino, T; Amoroso, C; Zachariah, R; van Griensven, J; Schneider, S; Finnegan, K; Cortas, C; Kamanzi, E; Hamon, J K; Hedt-Gauthier, B L

    2014-12-21

    Contexte : Partners In Health Rwanda, en collaboration avec le Ministère de la Santé, mène une approche multiple afin de développer les capacités de recherche du personnel de santé, surtout dans les zones rurales.Objectifs : Décrire les caractéristiques des participants et évaluer l'impact d'une série de séminaires d'introduction à la recherche dans trois hôpitaux de district ruraux du Rwanda.Schéma : Etude rétrospective de cohorte des participants au séminaire. Les données ont été recueillies à partir de dossiers personnels, de formulaires d'évaluation et de rétroaction.Résultats : Des 126 participants qui ont assisté à la série de séminaires de recherche, 70 (56%) étaient cliniciens et 56 (44%) personnel non-clinicien. Soixante et un (48%) ont obtenu leur certificat. Parmi ces derniers, le score médian d'évaluation des travaux était de 79%. Les participants lisaient beaucoup plus d'articles à 6 et 12 mois (médiane = 2 et 4 respectivement, comparé à 1 au départ, P < 0,01). On notait également une augmentation significative (P ⩽ 0,05) de l'implication dans des travaux de recherche rapportée par les intéressés eux-mêmes (28% au départ contre 59% à 12 mois) ainsi que de la participation à d'autres formations relatives à la recherche (36% au départ contre 65% à 12 mois).Conclusion : La série de séminaires d'introduction à la recherche a fourni une opportunité majeure d'engagement dans la recherche du personnel clinicien et non clinicien. Une telle activité est un élément clé d'un programme complet de renforcement des capacités de recherche dans les zones rurales et sert de point d'entrée pour des formations à la recherche plus avancées.

  20. Analyse unterschiedlicher Modellierungsvarianten des "Direct Power Injection" Verfahrens für die EMV Charakterisierung integrierter Schaltungen

    NASA Astrophysics Data System (ADS)

    Stürmer, U.; Ritzmann, S.; Jovic, O.; Wilkening, W.

    2009-05-01

    Dieser Beitrag analysiert zwei Ansätze zur Modellierung eines Teststandes zur Charakterisierung von integrierten Schaltungen mittels Direct Power Injection (DPI) auf einem Wafer. Die erste Variante ist zur Analyse bereits vorliegender integrierter Schaltungen nutzbar. Sie benötigt gemessene S-Parameterdaten, mit denen die an einem realen Messobjekt anliegenden Störspannungen frequenzabhängig bestimmt werden können. Die zweite Variante ist bereits anwendbar, bevor Silizium gefertigt worden ist. Sie modelliert einen Netzwerkanalysatorkanal der aus einer Signalquelle, einem Leistungsmesser und einem Verstärker mit nachgeschaltetem Richtkoppler und Entkoppelnetzwerken besteht. Zunächst werden die oben genannten verschiedenen Varianten der DPI-Streckenmodellierung dargestellt. Sie werden miteinander und anhand von Messdaten einer einfachen Teststruktur verglichen. Die Teststruktur besteht aus einem MOS-Transistor mit Arbeitswiderstand. Der Beitrag diskutiert Vor- und Nachteile der Varianten einschließlich Modellierungsaufwand und Simulationsgeschwindigkeit.

  1. The genus Sitothrips (Thysanoptera: Thripidae) with a new grass-living species from southern Iran.

    PubMed

    Minaei, Kambiz; Mound, Laurence

    2014-11-19

    One of the generic characters given by zur Strassen (2003) for species of the genus Sitothrips Priesner (1931) is the presence of 2-segmented maxillary palps. In contrast, a new species of this genus is described below from Iran in which the maxillary palps are clearly 3-segmented (Fig. 5). The genus was erected for arabicus Priesner from Egypt, a species now recorded widely among countries around the Mediterranean, from Morocco to southern Russia. Three further species are listed in Sitothrips: almargeniensis Titschack from Spain and Portugal, lindbergi zur Strassen from the Canary Islands and Morocco, and calcaratus (Savenko) from southern Russia. The identity of the latter species remains in some doubt as, in contrast to the other species, it was described as wingless and lacking ocelli (Savenko 1944), but zur Strassen (2003) provided an illustrated key to the other three species.

  2. Expertise bewerben und finden im Social Semantic Web

    NASA Astrophysics Data System (ADS)

    Polleres, Axel; Mochol, Malgorzata

    Im vorliegenden Beitrag diskutieren wir Rahmenbedingungen zur Kombination, Wiederverwendung und Erweiterung bestehender RDFVokabulare im Social Semantic Web. Hierbei konzentrieren wir uns auf das Anwendungsszenario des Auffindens und Bewerbens von Experten im Web oder Intranet. Wir präsentieren, wie RDF-Vokabulare einerseits und de facto Standardformate andererseits, die von täglich verwendeten Applikationen benutzt werden (z. B. vCard, iCal oder Dublin Core), kombiniert werden können, um konkrete Anwendungsfälle der Expertensuche und zum Management von Expertise zu lösen. Unser Fokus liegt darauf aufzuzeigen, dass für praktische Anwendungsszenarien nicht notwendigerweise neue Ontologien entwickelt werden müssen, sondern der Schlüssel vielmehr in der Integration von bestehenden, weit verbreiteten und sich ergänzenden Formaten zu einem kohärenten Netzwerk von Ontologien liegt. Dieser Ansatz garantiert sowohl direkte Anwendbarkeit von als auch niedrige Einstiegsbarrieren in Semantic Web-Technologien sowie einfache Integrierbarkeit in bestehende Applikationen. Die im Web verfügbaren und verwendeten RDFFormate decken zwar einen großen Bereich der Aspekte zur Beschreibung von Personen und Expertisen ab, zeigen aber auch signifikante Überlappungen. Bisher gibt es wenig systematische Ansätze, um diese Vokabulare zu verbinden, sei es in Form von allgemeingültigen Praktiken, die definieren, wann welches Format zu benutzen ist, oder in Form von Regeln, die Überlappungen zwischen einzelnen Formaten formalisieren. Der vorliegende Artikel analysiert, wie bestehende Formate zur Beschreibung von Personen, Organisationen und deren Expertise kombiniert und, wo nötig, erweitert werden können. Darüber hinaus diskutieren wir Regelsprachen zur Beschreibung von Formatüberlappungen sowie deren praktische Verwendbarkeit zur Erstellung eines Ontologie-Netzwerks zur Beschreibung von Experten.

  3. Transcendental Meditation

    ScienceCinema

    None

    2016-07-12

    K.Wallace, qui vient des Etats Unis, parle des effects physiologiques de la méditation transcendantale. Il a fait son bachelor en physique à l'Université de Los Angeles et son doctorat en physiologie aussi à Los Angeles, mais à l'Institut de Recherche sur le cerveau. Il travaille maintenat à Harvard Medical School ou il continue des recherches biochimiques et physiologiques sur l'application médicale de la méditation transcendantale. Il s'occupe principalement des maladies cardiaques et de hypertension artérielle.

  4. Littoral Infrared Ship Self Defence Technology Studies (Autodefense cotiere infrarouge des navires etudes technologiques)

    DTIC Science & Technology

    2014-05-01

    SET-088) Synthèse Ce groupe de travail a traité des aspects suivants de l’autodéfense côtière infrarouge : 1) La détection des missiles antinavires...recherche sur la propagation infrarouge a été un autre sujet d’intérêt pour le groupe de travail . Les activités principales de la recherche sur la...propagation IR ont concerné l’essai VAMPIRA avec le groupe de travail SET-056 (Intégration du Radar et de l’Autodéfense Infrarouge des Navires), l’analyse

  5. Speech Processing in Realistic Battlefield Environments (Le Traitement de la Parole en Environnement de Combat Realiste)

    DTIC Science & Technology

    2009-04-01

    parole et du langage multilingue commence à être reconnue comme un enjeu important par les organisations internationales civiles et militaires. Par...sur le développement et l’évaluation des applications multilingues de la parole et du langage . Pour stimuler la recherche et l’évaluation, le Groupe...Opérationnel de Recherche sur la Parole et le Langage (IST-031/TG-013) de l’OTAN a collationné des données vocales en environnement de combat. Ces

  6. Human Factors Research Task 2006-8722;111: AIMSsim Feature Development II

    DTIC Science & Technology

    2008-01-01

    perfectionné de surveillance multi- capteurs intégré (AIMS) – qui consistait à élaborer le logiciel pour une plate-forme de recherche conçue pour simuler...l’interface opérateur-machine et les commandes d’un système de surveillance multi- capteurs aéroporté. La plate-forme de recherche sert à évaluer les...intensification de lumière visible et à infrarouge ou ELVISS) qui est en cours de développement à RDDC Valcartier. Équipé de deux à cinq capteurs , le

  7. Transcendental Meditation

    SciTech Connect

    2005-11-29

    K.Wallace, qui vient des Etats Unis, parle des effects physiologiques de la méditation transcendantale. Il a fait son bachelor en physique à l'Université de Los Angeles et son doctorat en physiologie aussi à Los Angeles, mais à l'Institut de Recherche sur le cerveau. Il travaille maintenat à Harvard Medical School ou il continue des recherches biochimiques et physiologiques sur l'application médicale de la méditation transcendantale. Il s'occupe principalement des maladies cardiaques et de hypertension artérielle.

  8. What happens after participants complete a Union-MSF structured operational research training course?

    PubMed

    Guillerm, N; Tayler-Smith, K; Berger, S D; Bissell, K; Kumar, A M V; Ramsay, A; Reid, A J; Zachariah, R; Harries, A D

    2014-06-21

    Contexte : Huit cours de recherche opérationnelle (OR) structurée achevés de L'Union et Médecins sans Frontières pour des participants de pays à revenu faible ou intermédiaire. On ignore si les participants continuent à pratiquer la recherche opérationnelle après avoir suivi le cours.Objectifs : Déterminer 1) les activités de recherche des participants et de leurs institutions après la fin du cours ; 2) l'influence des bourses de recherche sur ces activités ; et 3) les activités des collègues n'ayant pas assisté au cours, stratifiées par sexe, région et statut professionnel.Schéma : Une enquête par questionnaire auto-administré envoyée par e-mail.Résultats : Sur 83 participants qui ont terminé le cours, 76 (92%) ont répondu au questionnaire. Après la fin du cours, 47 (62%) participants ont réalisé de nouveaux projets de recherche, 38 (50%) ont publié des articles (comparés à 25 [33%] qui en avaient publié avant le cours), 42 (55%) ont exposé des affiches ou présenté des résumés oraux lors de conférences, 33 (43%) ont été facilitateurs lors de cours suivants, 29 (38%) ont revu des articles scientifiques, 25 (33%) ont obtenu un financement ultérieur pour le recherche opérationnelle et 55 (72%) ont affirmé que leurs institutions étaient impliquées dans la mise en œuvre de recherche ou de renforcement des capacités. Les participants au cours ont eu une meilleure performance que les autres. Parmi ces derniers, les hommes et les participants venant d'Asie ont eu de meilleurs résultats que les femmes et les participants venant d'Afrique (P < 0,05).Conclusion : Une proportion significative de participants a continué à réaliser des recherches opérationnelles après la fin du cours. Ces constatations sont encourageantes en termes d'impact à long terme de ce modèle de renforcement des capacités.

  9. Pleurésie purulente à Nocardia asteroids

    PubMed Central

    Bopaka, Régis Gothard; Janah, Hind; El Khattabi, Wiam; Aichane, Abdelaziz; Afif, Hicham

    2014-01-01

    La pleurésie purulente à Nocardia asteroides est rare. Elle survient le plus souvent sur un terrain d'immunodépression. Nous rapportons une observation d'une pleurésie à Nocardia asteroides chez une patiente âgée de 60 ans, chez qui nous avons découvert un diabète. A travers ce travail les auteurs soulignent l'intérêt de la multiplication de prélèvements, de rechercher ce germe sur terrain d'immunodépression et en cas d'isolement, de rechercher la comorbidité. PMID:25574322

  10. Dissemination of student research in a canadian master of science in physical therapy programme.

    PubMed

    Salbach, Nancy M; O'Brien, Kelly; Evans, Cathy; Yoshida, Karen

    2013-01-01

    Objectif : Établir l'étendue de la présentation et de la publication ainsi que le moment de publication des travaux de recherche réalisés par des étudiants dans le cadre de leur maîtrise ès sciences en physiothérapie (M.Sc.PT) dans une université canadienne. Méthodologie : Les auteurs ont réalisé une étude transversale rétrospective des projets de recherche à la maîtrise ès sciences en physiothérapie réalisés de 2003 à 2009 par des groupe d'étudiants à la maîtrise qui ont élaboré un protocole de recherche, préparé les documents d'approbation éthique, recueilli les données, procédé à l'analyse et rédigé le manuscrit et les affiches sous la supervision de conseillers en recherche. Un courriel a été envoyé aux conseillers en recherche en vue d'obtenir des citations des présentations et des publications. Résultats : Les conseillers de 102 des 113 projets de recherche réalisés de 2003 à 2009 ont livré l'information demandée, soit un taux de réponse de 90,3%. Des 102 groupes de ces conseillers, 53,9% ont fait connaître les conclusions des études par des publications ou des présentations, 33,3% ont présenté au moins une conférence et 30,4% ont publié au moins un article dans une revue à comité de lecture. Le délai moyen de publication était de 21 mois. Près de la moitié des articles de revue (47%) ont été publiés dans Physiotherapy Canada. Conclusions : Un nombre modéré de groupes de recherche d'étudiants à la M.Sc.PT font connaître les conclusions de leurs travaux par des publications ou dans le cadre de présentations. Une recherche plus poussée sur les facteurs qui influent sur la diffusion de leurs travaux est nécessaire pour élaborer des stratégies qui pourront faciliter le transfert des connaissances.

  11. Developing RADARSAT’s METOC Capabilities in Support of Project Polar Epsilon

    DTIC Science & Technology

    2005-08-01

    pormettront aux Forces canadiornnos d’am~liorer leurs capacit6s op ~ rationnelles do surveillance et assureront A l’utilisatour uno plus grande confiance ý...fl Defence Research and Recherche et d~veloppement Deve-opfnent Canada pour ,a df1ense Canada DEFENCE !bJDEFENSE Developing RADARSAT’s METOC...accorde un contrat do recherche visant l’obtention do definitions et do roconimandlations do R et D. RWsultats Los vents do surface, los vagues et los

  12. Integration of Externally Carried Weapon Systems with Military Helicopters (L’Integration des Systemes d’Armes Transportes en Charge Externe sur les Helicopteres Militaires)

    DTIC Science & Technology

    1990-04-01

    structurales. Le rapport traite 6galement de questions op ~ rationnelles et de certains probl~mes spicifiques. Le teXte eat compiti par trois annexes: - Annexe I...origines modestes pendant la deuxiinme guerre mondiale o6 it~ a k6e deploye principalement conime plateforme d’observation et v~hicule de recherche et de...appropries de Ia communaute de I’OTAN. Des efforts considirables ont iti faits lors des recherches dc donneies pour assurer l’exhaustivit. Alors it eat

  13. Human Performance Assessment Methods

    DTIC Science & Technology

    1989-05-01

    deja aborde let problmes souleves par e’tude des performances humaines en situation op ~ rationnelle mais tr~s souvent il t’est av&r impossiblc de faire...La mission dii Groupe fit dl󈨁abortr inc batterie standardiq~e de tests et de rechercher et crs~er unc structure pour I𔄀change de donnees. La...fit de compiler ct dc publier in Annusire international des 6quipes de recherche en performances humaines. Cette publication. quoique loin d

  14. Digitalisierung in der Energiewirtschaft - empirische Untersuchung und Wertschöpfungskette

    NASA Astrophysics Data System (ADS)

    Dell, Timo

    Die Energiewirtschaft nutzt seit je her digitale Strukturen zur Umsetzung ihrer Prozesse. Durch den (neuen) verabschiedeten politischen Ordnungsrahmen - dem Gesetz zur Digitalisierung der Energiewende - und durch die rasante Fortentwicklung technologischer Strukturen ergeben sich jedoch die Wertschöpfungsstufen erweiternde, diversifizierende und innovative Möglichkeiten für Energieversorger (EVU) Geschäftsfelder auszubauen bzw. neue zu erschließen. Dabei ist die digitale (R)Evolution keine rein technische Umsetzung, sondern insbesondere auch eine unternehmensinterne, strategische und intern-kulturelle Herausforderung.

  15. Fahrerassistenzsysteme mit maschineller Wahrnehmung

    NASA Astrophysics Data System (ADS)

    Maurer, Markus; Stiller, Christoph

    Fahrerassistenzsysteme unterstützen den Fahrer in seiner Fahraufgabe und entlasten ihn dadurch gezielt. Viele Experten erwarten, dass Fahrerassistenzsysteme zur Sicherheit des Straßenverkehrs wesentlich beitragen werden. Zentrale wissenschaftliche und industrielle Herausforderungen bestehen zur Zeit in der Erforschung und Entwicklung maschineller Wahrnehmungsfähigkeiten, die eine angemessene Erfassung der Umwelt und deren fahrergerechte Integration in geeignete Fahrfunktionen leisten. Dieser Band basiert auf ausgewählten Vorträgen eines. Workshops in Walting (Altmühltal) und macht deren Inhalt in erweiterter Fassung zugänglich.

  16. Satellitengestützte Lokalisierung in urbanen Gebieten mit globalen Satellitennavigationssystemen

    NASA Astrophysics Data System (ADS)

    Wanielik, P. Reisdorf und G.

    2013-07-01

    Die Kenntnis des eigenen Standortes an jedem Punkt der Erde und zu jeder Zeit ist eine wichtige Voraussetzung für viele Anwendungen sowohl im Straßenverkehr als auch zur Orientierung einzelner Personen. Wurde bisher das bekannte GPS vorwiegend eingesetzt, so existiert mit GLONASS und entsprechenden Mehrsystemempfängern die Möglichkeit der Nutzung von mehreren Satellitensystemen. Dadurch erhöht sich augenblicklich die Anzahl zur Verfügung stehender Satelliten, wodurch sich bestimmte Positionierungseigenschaften wie Verfügbarkeit, Integrität und Genauigkeit verbessern lassen.

  17. Abgasnachbehandlung

    NASA Astrophysics Data System (ADS)

    Wirth, Ralf; Raatz, Thorsten

    Bisher wurde die Emissionsminderung beim Dieselmotor vorwiegend durch inner motorische Maßnahmen bewirkt. Bei vielen Diesel-Fahrzeugen werden die vom Motor freigesetzten Emissionen (Rohemissionen) jedoch die zukünftig in Europa, den USA und Japan geltenden Emissionsgrenzwerte überschreiten. Die erforderlichen hohen Minderungsraten lassen sich voraussichtlich nur durch eine effiziente Kombination von innermotorischen und nachmotorischen Maßnahmen erreichen. Analog zur bewährten Vorgehensweise bei Benzinfahrzeugen werden deshalb auch für Dieselfahrzeuge verstärkt Systeme zur Abgas - nachbehandlung (nachmotorische Emis sions minderung) entwickelt.

  18. Hinderniserkennung und -verfolgung mit einer PMD-kamera im automobil

    NASA Astrophysics Data System (ADS)

    Schamm, Thomas; Vacek, Stefan; Natroshvilli, Koba; Marius Zöllner, J.; Dillmann, Rüdiger

    Die Detektion von Hindernissen vor dem Automobil ist eine Hauptanforderung an moderne Fahrerassistenzsysteme (FAS). In dieser Arbeit wird ein System vorgestellt, das mit Hilfe einer PMDKamera (Photomischdetektor) Hindernisse auf der Fahrspur erkennt und deren relevante Parameter bestimmt. Durch die PMD-Kamera werden zunächst 3D-Tiefenbilder der Fahrzeugumwelt generiert. Nach einem initialen Filterprozess werden im Tiefenbild mit Hilfe eines Bereichswachstumsverfahrens Hindernisse gesucht. Zur Stabilisierung des Verfahrens und zur Parameterberechnung wird ein Kaiman Filter eingesetzt. Das Ergebnis ist eine Liste aller Hindernisse im Fahrbereich des Automobils.

  19. Ökophysik: Plaudereien über das Leben auf dem Land, im Wasser und in der Luft

    NASA Astrophysics Data System (ADS)

    Nachtigall, W.

    Prof. em. Dr. rer. nat. Werner Nachtigall, geb. 1934, war als Zoophysiologe und Biophysiker Leiter des Zoologischen Instituts der Universität des Saarlandes in Saarbrücken. In Forschung und Ausbildung hat er sich insbesondere mit Aspekten der Technischen Biologie und Bionik befasst und mit seinen Forschergruppen viele Basisdaten insbesondere zur Ökologie, Physiologie und Physik des Fliegens und Schwimmens aber auch zur Stabilität beispielsweise der Gräser erarbeitet. Lebewesen überraschen immer wieder durch ihre "Biodiversität", ihre hochspezifischen Ausgestaltungen und Anpassungen.

  20. Einsteins Spuren in den Archiven der Wissenschaft: Physikgeschichte

    NASA Astrophysics Data System (ADS)

    Marx, Werner

    2005-07-01

    Die Erwähnungen und Zitierungen von Einsteins Arbeiten dokumentieren lediglich den quantifizierbaren Anteil von Einsteins Beitrag zur Physik. Gleichwohl belegen sie die außergewöhnliche Resonanz und Langzeitwirkung seiner Arbeiten. Die Häufigkeit der Zitierungen entspricht nicht der allgemeinen Einschätzung ihrer Bedeutung. Insbesondere die Pionierarbeiten werden inzwischen als bekannt vorausgesetzt und nicht mehr explizit zitiert. Interessanterweise ist seine nach 1945 meist zitierte Arbeit nicht eine der Pionierarbeiten zur Quantenphysik oder Relativitätstheorie, sondern jene aus dem Jahr 1935 zum berühmten Einstein-Podolsky-Rosen-Paradoxon.

  1. Anbindung des SISIS-SunRise-Bibliothekssystems an das zentrale Identitätsmanagement

    NASA Astrophysics Data System (ADS)

    Ebner, Ralf; Pretz, Edwin

    Wir berichten über Konzepte und Implementierungen zur Datenprovisionierung aus den Personenverwaltungssystemen der Technischen Universität München (TUM) über das zentrale Metadirectory am Leibniz-Rechenzentrum (LRZ) in das SISIS-SunRise-Bibliothekssystem der Universitätsbibliothek der TUM (TUB). Es werden drei Implementierungsvarianten diskutiert, angefangen von der Generierung und Übertragung einfacher CSV-Dateien über ein OpenLDAP-basiertes Konzept als Backend für die SISIS-Datenbank bis zur endgültigen Implementierung mit dem OCLC IDM Connector.

  2. MEOSAR Cost Escalation Risk

    DTIC Science & Technology

    2014-02-25

    Defence Research and Development Canada Recherche et développement pour la défense Canada DRDC-RDDC-2014-L Produced for Peter Iburg, CMA, Senior ......SME’s sensitivity analysis of their cost estimates. Senior project management’s input provides the majority opinion in the base estimates while DCostS’s

  3. Une Experience C.R.A.P.E.L. (An Experience at C.R.A.P.E.L.). Melanges Pedagogiques, 1972.

    ERIC Educational Resources Information Center

    Lagarde, J. P.; Boulanger, C.

    In July of 1971 and of 1972, meetings were held, in York and Nancy, respectively, organized by the University of York's Language Teaching Centre and by the Centre de Recherches et d'Applications Pedagogiques en Langues. These meetings were attended by 80 British teachers of French and 80 French teachers of English at the secondary level. The…

  4. Apprentissage auto-dirige: Quand les chiffres parlent (Self-Directed Learning: Figures Speak for Themselves).

    ERIC Educational Resources Information Center

    Abe, Daniele; Gremmo, Marie-Jose

    The functioning of the semi-autonomous learning system (SAAS) at the Centre de Recherches et d'Applications Pedagogiques en Langues (CRAPEL) was surveyed for the academic year 1980-81. Detailed data were collected about learners' aims, language level, and their assessment of the SAAS, as well as about the way they actually used the system. This…

  5. A Low-Frequency, Tow-Powered Sound Source

    DTIC Science & Technology

    1990-06-01

    DISPOSITIFS ELECTRONIQUES BASSE FREQUENCE Chairman: Jean-Nodl DECARPIGNY 1l0- ISEN-RECHERCHE, Lille, France SESSl 15h00- 15h40 S ma ELECTRONIC NEEDS...Marconi Command and Control Systems, New Parks, Leicester, England 15h40- 16h20 ELECTRONIC SYSTEMS MODELING MODELISATION DES SYSTEMES ELECTRONIQUES

  6. Factors Affecting Attraction, Recruitment, and Retention of NATO Military Medical Professionals (Facteurs d’influence sur l’attraction, le recrutement et la fidelisation des professionnels de sante militaires de l’otan)

    DTIC Science & Technology

    2012-12-01

    de la RTO (Organisation OTAN pour la Recherche et la Technologie) a créé un Groupe de travail (HFM-213) concernant les Facteurs d’influence sur...Meeting in Cologne, 15-16 June 2011; • Meeting in Brussels, 19-21 October 2011; and • Final meeting in Prague, 27 February – 1 March 2012. The

  7. Discussing Sexual Orientation and Gender in Classrooms: A Testimonial-Based Approach to Fighting Homophobia in Schools

    ERIC Educational Resources Information Center

    Richard, Gabrielle; Vallerand, Olivier; Petit, Marie-Pier; Charbonneau, Amélie

    2015-01-01

    To fight homophobia in schools in Québec, many teachers rely on community organizations such as the Groupe de Recherche et d'Intervention Sociale (Research and Social Intervention Group) to address sexual diversity in class. This article documents major outcomes of these workshops as seen by students. Students identified topics related to…

  8. New Trends for New Needs in Instructional Technology Theory and Development.

    ERIC Educational Resources Information Center

    Morin, Andre

    This report shares insights on varied experiences in action research at the university level and describes methods for involving subjects in research. Examples used include case histories of two projects: the Projet de recherche et d'intervention a la maison (PRIM), a research project on home intervention; and the Ford Teaching Project. Based on…

  9. International Congress on Transposable Elements (ICTE) 2012 in Saint Malo and the sea of TE stories.

    PubMed

    Ainouche, Abdelkader; Bétermier, Mireille; Chandler, Mick; Cordaux, Richard; Cristofari, Gaël; Deragon, Jean-Marc; Lesage, Pascale; Panaud, Olivier; Quesneville, Hadi; Vaury, Chantal; Vieira, Cristina; Vitte, Clémentine

    2012-10-30

    An international conference on Transposable Elements (TEs) was held 21-24 April 2012 in Saint Malo, France. Organized by the French Transposition Community (GDR Elements Génétiques Mobiles et Génomes, CNRS) and the French Society of Genetics (SFG), the conference's goal was to bring together researchers from around the world who study transposition in diverse organisms using multiple experimental approaches. The meeting drew more than 217 attendees and most contributed through poster presentations (117), invited talks and short talks selected from poster abstracts (48 in total). The talks were organized into four scientific sessions, focused on: impact of TEs on genomes, control of transposition, evolution of TEs and mechanisms of transposition. Here, we present highlights from the talks given during the platform sessions. The conference was sponsored by Alliance pour les sciences de la vie et de la santé (Aviesan), Centre national de la recherche scientifique (CNRS), Institut national de la santé et de la recherche médicale (INSERM), Institut de recherche pour le développement (IRD), Institut national de la recherche agronomique (INRA), Université de Perpignan, Université de Rennes 1, Région Bretagne and Mobile DNA. CHAIR OF THE ORGANIZATION COMMITTEE: Jean-Marc Deragon ORGANIZERS: Abdelkader Ainouche, Mireille Bétermier, Mick Chandler, Richard Cordaux, Gaël Cristofari, Jean-Marc Deragon, Pascale Lesage, Didier Mazel, Olivier Panaud, Hadi Quesneville, Chantal Vaury, Cristina Vieira and Clémentine Vitte.

  10. Hidden sketches by Leonardo da Vinci revealed

    NASA Astrophysics Data System (ADS)

    Dumé, Belle

    2009-02-01

    Three drawings on the back of Leonardo da Vinci's The Virgin and Child with St Anne (circa 1508) have been discovered by researchers led by Michel Menu from the Centre de Recherche et de Restauration des Musées de France (C2RMF) and the Louvre Museum in Paris.

  11. Integrated Target Acquisition and Fire Control Systems: Avionics Panel Symposium Held in Ottawa, Canada on 7-10 October 1991 (Systemes Integres d’Acquisition d’Objectifs et de Conduite de Tir)

    DTIC Science & Technology

    1992-02-01

    ADDRESS by Major-General D.R. Williams Chief Air Doctrine and Operatiols National Defence Headquarters Major-General George R. Pearkes Bui.ding Ottawa...environnement de type champ de bataille , de nombreux objets peuvent r~pondre 4 Le deplaceinent recherch6 est one translation pure ce3 crit~es

  12. La capture et l'enfouissement doivent entrer dans une phase industrielle

    SciTech Connect

    Bonneville, Alain

    2011-07-01

    This is an invited short paper in the French popular science magazine "La Recherche" (http://www.larecherche.fr/) . This contribution seen as the Pro-CCS will put in regards to an Anti-CCS contribution in their Debate section. An English translation is provided.

  13. Topical Meeting on Laser Techniques for Extreme Ultraviolet Spectroscopy, 8-10 March 1982, Boulder, Colorado.

    DTIC Science & Technology

    1982-03-01

    Excited States In Molecules, Jacques Lukasik, Stephen C. Wallace* and William R. Greent, Laboratoire d’Optique Quantique du Centre Na- tional de /a...MOLECULES Jacques LUKASIK, Stephen C. WALLACE(a) and William R. GREEN(b) Laboratoire d’Optique Quantique du Centre National de la Recherche Scientifique

  14. Derrida's Right to Philosophy, Then and Now

    ERIC Educational Resources Information Center

    Willinsky, John

    2009-01-01

    In this essay, a tribute to Jacques Derrida's educational efforts at expanding access to current work in philosophy, John Willinsky examines his efforts as both a public right and an element of academic freedom that bear on the open access movement today. Willinsky covers Derrida's extension and outreach work with the Groupe de Recherches pour…

  15. Evaluation in an Autonomous Learning Scheme. Melanges Pedagogiques, 1977.

    ERIC Educational Resources Information Center

    Henner-Stanchina, C.; Holec, H.

    This document consists of a discussion of the place and nature of evaluation within the autonomous learning scheme developed by the Centre de Recherches et d'Applications Pedagogiques en Langues (C.R.A.P.E.L.). The center's commitment to the development of an autonomous learning scheme dates back several years. It is the outcome of an attempt to…

  16. The Education and Training of Physics Teachers Worldwide. A Survey.

    ERIC Educational Resources Information Center

    Davies, Brian, Ed.

    The Group Internationale de Recherche sur l'Enseignment de la Physique (GIREP), known in English as The International Research Group on Physics Teaching, is an independent association for the improvement of physics teaching in schools and, to a lesser extent, at the interface between school and university. Provided in this three-part book is…

  17. Compte rendu d'une experience pedagogique. L'Enseignement de la competence de communication en langues secondes. (An Account of a Pedagogical Experiment. The Teaching of Communicative Competence in Second Languages). Acts of the Colloguium of the Swiss Interuniversity Commission for Applied Linguistics. CILA Bulletin.

    ERIC Educational Resources Information Center

    Brunet, J.; Jammot, M. T.

    Three methodological "hypotheses" elaborated by the "Centre interuniversitaire de recherche pour le recyclage des maitres d'italien" are presented here. These hypotheses came from three teams of teachers working from different perspectives on sets of lessons for beginners of all ages. Each team's operative assumptions, type of text, guiding…

  18. Determination of lead in igneous rocks by differential pulse anodic stripping voltammetry at an HMDE.

    PubMed

    Calderoni, G

    1981-01-01

    A versatile and sensitive voltammetric method has been used for the determination of lead in seven USGS standard rocks and in two CRPG (Centre des Recherches Pétrografiques et Géochimiques, Nancy) standard rocks. The results, showing satisfactory precision and accuracy, are discussed with respect to the sample treatment and the voltammetric method.

  19. Passive 19.3 GHz Radiometer and Aerosol Data from the North Sea during MARSEN I, September-October 1979.

    DTIC Science & Technology

    1980-08-13

    MODIFIED CONTINENTAL 3.0- [ 0.17 2! y > 0.06, CONTINENTAL, POLLUTED CONTINENTAL 3. ro 2.0- 1.0 20 30 40 SO 60 70 so 90 100 R. H. (% Fig. 15 - Plot...Chemistry of Sea/Air Particulate Exchange Processes; Summary and Recommendations, Journal de Recherches Atmospheriques , 8, pp 509-513. (3) Blanchard

  20. Coalition Interoperability Measurement Frameworks Literature Survey

    DTIC Science & Technology

    2011-08-01

    contemporain de bataille et de mission; que des recherches empiriques et sur le terrain soient entreprises aussitôt que possible afin de tirer parti des...gouvernementales et les autres intervenants potentiels dans l’espace de bataille et de mission. 2. Lors d’événements imprévus, l’agilité organisationnelle à

  1. Computational Simulation of Vibrational Overtone Spectral Regions: Sarin

    DTIC Science & Technology

    2006-12-01

    future de la m6thode de simulation spectrale docu- ment~e ici devrait ktre entreprise en acqu6rant les r6gions spectrales exp~rimentales de plusleurs...effectu6s sur un r~seau informatique p~dagogique financ6 par le gouvernement . 11 serait avantageux, pour Recherche et d6veloppement pour la d6fense - Suffield

  2. Experiments in English for Special Purposes. Melanges Pedagogiques, 1975.

    ERIC Educational Resources Information Center

    Duda, R.; And Others

    This report describes four experiments in English for Special Purposes conducted by or involving the Centre de Recherches et d'Applications Pedagogiques en Langues. English for Special Purposes is discussed in relation to language skills, grammatical and functional progression, "autonomization" and individualization of language acquisition, and…

  3. Generation of Constructs for DNA-Directed RNA Interference of Venezuelan Equine Encephalitis Virus Genes

    DTIC Science & Technology

    2006-12-01

    son utilisation potenuielle conine arme biologique pr ~;enu a penser qu’i] existe tin besoin dapprofondir ]a recherche dans le domaine sp~cifique des...Plans fulurs :Les \\ ctecurs decxpi ession de petils ARMi scront tesi ~s pour leur capacit a’ soumetie a1 effet de choc trois e:’nes EY essentick ci til

  4. European Reacting Flow Research: A Final Assessment.

    DTIC Science & Technology

    1987-09-03

    are in flame-front part of the laboratory of Molecular Ener- dynamics, premixed stabilized flames, get cis and Nacroscopic Combustion. The flame...Dedex FRANCE FRANCE Professor P. Clavin Professor Amable Lifian laboratoire de Recherche en Combustion Escuela Tecnica Suprior de Ingenieros Service 252

  5. Experiments in English for Special Purposes. Melanges Pedagogiques, 1975.

    ERIC Educational Resources Information Center

    Duda, R.; And Others

    This report describes four experiments in English for Special Purposes conducted by or involving the Centre de Recherches et d'Applications Pedagogiques en Langues. English for Special Purposes is discussed in relation to language skills, grammatical and functional progression, "autonomization" and individualization of language acquisition, and…

  6. Supervisory Control of Multiple Uninhabited Systems Methodologies and Human-Robot Interface Technologies Technical (Commande et Surveillance de multiples systemes sans pilote Methodologies et technologies d’interfaces homme-robot)

    DTIC Science & Technology

    2012-12-01

    generation and application of state-of-the- art , validated knowledge for defence and security purposes. S&T activities embrace scientific research...résultats ont été réunis en un nouveau projet de modèle de commande et surveillance qui tient compte de tous les aspects de recherche prioritaire. Deux

  7. AGARD Flight Test Techniques Series. Volume 19. Simulation in Support of Flight Testing. (la Simulation pour le soutien des essais en vol)

    DTIC Science & Technology

    2000-09-01

    point where the amount of effort required to design, build, engine and spin chute . Many of the other cockpit functions and conduct V&V on the displays...HONGRIE PORTUGAL Directeur - Recherche et d~veloppement - Department for Scientific Estado Maior da Forga Afrea Communications et gestion de Analysis

  8. Improvements to the Staniforth-Mitchell Barotropic Numerical Weather Prediction Code.

    DTIC Science & Technology

    1986-10-15

    bisection procedure described above requires modification. Although the underlying strategy is unchanged, different software Is required. In this instance...Monterey, California 93943 9. Doctor A. N. Staniforth I Recherche en Prevision Numerique Atmospheric Environment Service ’."J Dorval, Quebec H9P IJ3

  9. Indexation Rules for Metallurgy in PASCAL. Original Title: Regles d'Indexation de la Metallurgie'--Technical Note Issued by Informascience--January 1980. Translated by Marie Wallin.

    ERIC Educational Resources Information Center

    Royal Inst. of Tech., Stockholm (Sweden). Library.

    The indexing rules presented are designed for use with a new French-German database on metallurgy being developed under an agreement by CNRS (Centre National de la Recherche Scientifique, Paris) and BAM (Bundesanstalt fur Materialprufung, Berlin). The new database, which will feature multilingual titles and index terms (French-German-English-) and…

  10. Noise and Man 󈨡. Noise as a Public Health Problem. Proceedings of the International Congress (6th) Held in Nice on July 5 - 9, 1993

    DTIC Science & Technology

    1993-07-01

    l’Ouest et le Japon . Ceci est refl&t6 dans plus de 60 contributions dans ce domaine de recherche A ce congres. Nous avons dO structurer ces nombreuses...en particulier en Europe et au Japon - prdvoient le ddveloppemnent de groupe mocopropulseurs A faible dmission de bruit et de pneus silencicux. Les

  11. Steering Committee on Educational Documentation and Abstracting Services

    ERIC Educational Resources Information Center

    Educational Documentation and Information, 1972

    1972-01-01

    Background information, functions, activities, responsibilities, and future plans are outlined for each of the participating centers: Documentation Centre, Ministry of Education, Cairo; National Center of Educational Communication, Washington; Institut Romand de Recherche et de Documentation Pedagogique, Neuchatel; Unesco Regional Office for…

  12. Discussing Sexual Orientation and Gender in Classrooms: A Testimonial-Based Approach to Fighting Homophobia in Schools

    ERIC Educational Resources Information Center

    Richard, Gabrielle; Vallerand, Olivier; Petit, Marie-Pier; Charbonneau, Amélie

    2015-01-01

    To fight homophobia in schools in Québec, many teachers rely on community organizations such as the Groupe de Recherche et d'Intervention Sociale (Research and Social Intervention Group) to address sexual diversity in class. This article documents major outcomes of these workshops as seen by students. Students identified topics related to…

  13. Derrida's Right to Philosophy, Then and Now

    ERIC Educational Resources Information Center

    Willinsky, John

    2009-01-01

    In this essay, a tribute to Jacques Derrida's educational efforts at expanding access to current work in philosophy, John Willinsky examines his efforts as both a public right and an element of academic freedom that bear on the open access movement today. Willinsky covers Derrida's extension and outreach work with the Groupe de Recherches pour…

  14. Indexation Rules for Metallurgy in PASCAL. Original Title: Regles d'Indexation de la Metallurgie'--Technical Note Issued by Informascience--January 1980. Translated by Marie Wallin.

    ERIC Educational Resources Information Center

    Royal Inst. of Tech., Stockholm (Sweden). Library.

    The indexing rules presented are designed for use with a new French-German database on metallurgy being developed under an agreement by CNRS (Centre National de la Recherche Scientifique, Paris) and BAM (Bundesanstalt fur Materialprufung, Berlin). The new database, which will feature multilingual titles and index terms (French-German-English-) and…

  15. France Sets Out to Democratize Science.

    ERIC Educational Resources Information Center

    Dickson, David

    1982-01-01

    Discusses proposed governmental science policy reforms, including administrative reforms of Centre National de la Recherche Scientifique, French equivalent to National Science Foundation. Indicates junior scientists, lab assistants, and technicians will be included in decision making and scientists will be barred from heading research terms for…

  16. Documenting and Researching Endangered Languages: The Pangloss Collection

    ERIC Educational Resources Information Center

    Michailovsky, Boyd; Mazaudon, Martine; Michaud, Alexis; Guillaume, Séverine; François, Alexandre; Adamou, Evangelia

    2014-01-01

    The Pangloss Collection is a language archive developed since 1994 at the Langues et Civilisations à Tradition Orale (LACITO) research group of the French Centre National de la Recherche Scientifique (CNRS). It contributes to the documentation and study of the world's languages by providing free access to documents of connected, spontaneous…

  17. Passion Research: A Joint Venture To Interest High School Students in Chemistry.

    ERIC Educational Resources Information Center

    Carriere, Francois J.; Abouaf, Madeleine

    1997-01-01

    Describes a joint venture between the Centre National de la Recherche Scientifique (CNRS) and the Department of Education in France that was created to allow students to do practical scientific work with the help of a CNRS researcher. Presents two practical projects done by students on organic polymers and on color. Concludes that this increases…

  18. Actes du colloque sur la didactique des langues aujourdi'hui: Pratiques et realite. (29 Sept./1 Oct. 1983) [Proceedings of a Colloquium on the Teaching of Modern Languages Today: Practice and Reality. (September 29-October 1, 1983)].

    ERIC Educational Resources Information Center

    Travaux Neuchatelois de Linguistique (TRANEL), 1984

    1984-01-01

    The eight papers in this collection include: "Un enseignant de langues a la recherche de la pierre philosophale" (A Language Teacher in Search of the Philosopher's Stone); "Apprentissage autodirige: Compte rendu d'experience 1978-83" (Self-Directed Learning: Report of Experience 1978-83); "Teaching Without a Language Syllabus But With a Linguistic…

  19. Documenting and Researching Endangered Languages: The Pangloss Collection

    ERIC Educational Resources Information Center

    Michailovsky, Boyd; Mazaudon, Martine; Michaud, Alexis; Guillaume, Séverine; François, Alexandre; Adamou, Evangelia

    2014-01-01

    The Pangloss Collection is a language archive developed since 1994 at the Langues et Civilisations à Tradition Orale (LACITO) research group of the French Centre National de la Recherche Scientifique (CNRS). It contributes to the documentation and study of the world's languages by providing free access to documents of connected, spontaneous…

  20. TDEM AND NUMIS (PLUS) SOUNDINGS AT THE ASH MEADOWS NATIONAL WILDLIFE REFUGE: A CASE STUDY

    EPA Science Inventory

    During the summer of 2002, a cooperative project between the U.S. Geological Survey, the U.S. Environmental Protection Agency, and the Bureau de Recherches Geologiques et Minieres was undertaken to evaluate and gain knowledge of the Iris NUMIS instrument. The system was deployed ...