LET and ion-species dependence for cell killing and mutation induction in normal human fibroblasts.

PubMed

Tsuruoka, Chizuru; Suzuki, Masao; Fujitaka, Kazunobu

2003-10-01

We have been studying LET and ion species dependence of RBE values in cell killing and mutation induction. Normal human skin fibroblasts were irradiated with heavy-ion beams such as carbon (290 Mev/u and 135 Mev/u), neon (230 Mev/u and 400 Mev/u), silicon (490 Mev/u) and iron (500 Mev/u) ion beams, generated by Heavy Ion Medical Accelerator in Chiba (HIMAC) at National Institute of Radiological Sciences (NIRS). Cell killing effect was detected as reproductive cell death using a colony formation assay. Mutation induction in hprt locus was detected to measure 6-thioguanine resistant colonies. The RBE-LET curves of cell killing and mutation induction were different each ion beam. So, we plotted RBE for cell killing and mutation induction as function of Z*2/beta2 instead of LET. RBE-Z*2/beta2 curves of cell killing indicated that the discrepancy of RBE-LET curves was reconciled each ion species. But RBE-Z*2/beta2 curves of mutation induction didn't corresponded between carbon- and silicon-ion beams. These results suggested that different biological endpoints may be suitable for different physical parameter, which represent the track structure of energy deposition of ion beams.

Performance of a Water Recirculation Loop Maintenance Device and Process for the Advanced Spacesuit Water Membrane Evaporator

NASA Technical Reports Server (NTRS)

Steele, John W.; Rector, Tony; Bue, Grant C.; Campbell, Colin; Makinen, Janice

2013-01-01

A dual-bed device to maintain the water quality of the Advanced Spacesuit Water Membrane Evaporation (SWME) water recirculation loop has been designed and is undergoing testing. The SWME is a heat rejection device under development at the NASA Johnson Space Center to perform thermal control for advanced spacesuits. One advantage to this technology is the potential for a significantly greater degree of tolerance to contamination when compared to the existing Sublimator technology. The driver for the development of a water recirculation maintenance device is to further enhance this advantage through the leveraging of fluid loop management lessons-learned from the International Space Station (ISS). A bed design that was developed for a Hamilton Sundstrand military application, and considered for a potential ISS application with the Urine Processor Assembly, provides a low pressure drop means for water maintenance in a recirculation loop. The bed design is coupled with high capacity ion exchange resins, organic adsorbents, and a cyclic methodology developed for the Extravehicular Mobility Unit (EMU) Transport Water loop. The bed design further leverages a sorbent developed for ISS that introduces a biocide in a microgravity-compatible manner for the Internal Active Thermal Control System (IATCS). The leveraging of these water maintenance technologies to the SWME recirculation loop is a unique demonstration of applying the valuable lessons learned on the ISS to the next generation of manned spaceflight Environmental Control and Life Support System (ECLSS) hardware.

Design and Evaluation of a Water Recirculation Loop Maintenance Device for the Advanced Spacesuit Water Membrane Evaporator

NASA Technical Reports Server (NTRS)

Steele, John W.; Rector, Tony; Bue, Grant C.; Campbell, Colin; Makinen, Janice

2012-01-01

A dual-bed device to maintain the water quality of the Advanced Spacesuit Water Membrane Evaporation (SWME) water recirculation loop has been designed and is undergoing testing. The SWME is a heat rejection device under development at the NASA Johnson Space Center to perform thermal control for advanced spacesuits. One advantage to this technology is the potential for a significantly greater degree of tolerance to contamination when compared to the existing sublimator technology. The driver for the development of a water recirculation maintenance device is to further enhance this advantage through the leveraging of fluid loop management lessons learned from the International Space Station (ISS). A bed design that was developed for a Hamilton Sundstrand military application, and considered for a potential ISS application with the Urine Processor Assembly, provides a low pressure drop means for water maintenance in a recirculation loop. The bed design is coupled with high-capacity ion exchange resins, organic adsorbents, and a cyclic methodology developed for the Extravehicular Mobility Unit Transport Water Loop. The bed design further leverages a sorbent developed for the ISS that introduces a biocide in a microgravity-compatible manner for the Internal Active Thermal Control System. The leveraging of these water maintenance technologies to the SWME recirculation loop is a unique demonstration of applying the valuable lessons learned on the ISS to the next generation of crewed spaceflight Environmental Control and Life Support System hardware.

Design and Evaluation of a Water Recirculation Loop Maintenance Device for the Advanced Spacesuit Water Membrane Evaporator

NASA Technical Reports Server (NTRS)

Steele, John W.; Rector, Tony; Bue, Grant C.; Campbell, Colin; Makinen, Janice

2011-01-01

A dual-bed device to maintain the water quality of the Advanced Spacesuit Water Membrane Evaporation (SWME) water recirculation loop has been designed and is undergoing testing. The SWME is a heat rejection device under development at the NASA Johnson Space Center to perform thermal control for advanced spacesuits. One advantage to this technology is the potential for a significantly greater degree of tolerance to contamination when compared to the existing Sublimator technology. The driver for the development of a water recirculation maintenance device is to further enhance this advantage through the leveraging of fluid loop management lessons-learned from the International Space Station (ISS). A bed design that was developed for a Hamilton Sundstrand military application, and considered for a potential ISS application with the Urine Processor Assembly, provides a low pressure drop means for water maintenance in a recirculation loop. The bed design is coupled with high capacity ion exchange resins, organic adsorbents, and a cyclic methodology developed for the Extravehicular Mobility Unit (EMU) Transport Water loop. The bed design further leverages a sorbent developed for ISS that introduces a biocide in a microgravity-compatible manner for the Internal Active Thermal Control System (IATCS). The leveraging of these water maintenance technologies to the SWME recirculation loop is a clear demonstration of applying the valuable lessons learned on the ISS to the next generation of manned spaceflight Environmental Control and Life Support System (ECLSS) hardware.

Performance of a Water Recirculation Loop Maintenance Device and Process for the Advanced Spacesuit Water Membrane Evaporator

NASA Technical Reports Server (NTRS)

Rector, Tony; Steele, John W.; Bue, Grant C.; Campbell, Colin; Makinen, Janice

2012-01-01

A water loop maintenance device and process to maintain the water quality of the Advanced Spacesuit Water Membrane Evaporation (SWME) water recirculation loop has been undergoing a performance evaluation. The SWME is a heat rejection device under development at the NASA Johnson Space Center to perform thermal control for advanced spacesuits. One advantage to this technology is the potential for a significantly greater degree of tolerance to contamination when compared to the existing Sublimator technology. The driver for the water recirculation maintenance device and process is to further enhance this advantage through the leveraging of fluid loop management lessons-learned from the International Space Station (ISS). A bed design that was developed for a Hamilton Sundstrand military application, and considered for a potential ISS application with the Urine Processor Assembly, provides a low pressure drop means for water maintenance in a recirculation loop. The bed design is coupled with high capacity ion exchange resins, organic adsorbents, and a cyclic methodology developed for the Extravehicular Mobility Unit (EMU) Transport Water loop. The maintenance process further leverages a sorbent developed for ISS that introduces a biocide in a microgravity-compatible manner for the Internal Active Thermal Control System (IATCS). The leveraging of these water maintenance technologies to the SWME recirculation loop is a unique demonstration of applying the valuable lessons learned on the ISS to the next generation of manned spaceflight Environmental Control and Life Support System (ECLSS) hardware. This

Inductive ion acceleration and heating in picket fence geometry: Theory and simulations

NASA Astrophysics Data System (ADS)

Leboeuf, J. N.; Dawson, J. M.; Ratliff, S. T.; Rhodes, M.; Luhmann, N. C., Jr.

1982-11-01

Particle simulations and analytic theory confirm the experimental observation of preferential ion acceleration and heating by an inductive electric field Edc in picket-fence geometry. The ions which are unmagnetized over most of the current channel are freely accelerated by the inductive field; the magnetized electrons are tied to the field lines and do not run away as long as the binding ev×B/c force is greater than the detrapping inductive force eEdc. Consequently, most of the current is carried by the ions which are also Ohmically heated.

The effect of the inductive electric field on ion poloidal rotation in all collisionality regimes for the primary ions in tokamaks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pan Chengkang; Wang Shaojie; Institute of Plasma Physics, Chinese Academy of Sciences, Hefei, 230031

2007-11-15

The expression for the poloidal rotation velocity of the primary ions that is caused by the parallel inductive electric field in tokamaks and valid in all collisionality regimes is derived via the Hirshman-Sigmar moment approach. Also the expression of the collisional impurity ions poloidal rotation velocity that is caused by the parallel inductive electric field in tokamaks is derived. The poloidal rotation velocities of the primary ions and the impurity ions are sensitive to the primary ion collisionality parameter and the impurity strength parameter. The poloidal rotation velocities of the primary ions and the impurity ions decrease with the primarymore » ion collisionality parameter and decrease with the impurity strength parameter.« less

Experimental measurement of the 4-d transverse phase space map of a heavy ion beam

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hopkins, H S

1997-12-01

The development and employment of a new diagnostic instrument for characterizing intense, heavy ion beams is reported on. This instrument, the ''Gated Beam Imager'' or ''GBI'' was designed for use on Lawrence Livermore National Laboratory Heavy Ion Fusion Project's ''Small Recirculator'', an integrated, scaled physics experiment and engineering development project for studying the transport and control of intense heavy ion beams as inertial fusion drivers in the production of electric power. The GBI allows rapid measurement and calculation of a heavy ion beam's characteristics to include all the first and second moments of the transverse phase space distribution, transverse emittance,more » envelope parameters and beam centroid. The GBI, with appropriate gating produces a time history of the beam resulting in a 4-D phase-space and time ''map'' of the beam. A unique capability of the GBI over existing diagnostic instruments is its ability to measure the ''cross'' moments between the two transverse orthogonal directions. Non-zero ''cross'' moments in the alternating gradient lattice of the Small Recirculator are indicative of focusing element rotational misalignments contributing to beam emittance growth. This emittance growth, while having the same effect on the ability to focus a beam as emittance growth caused by non-linear effects, is in principle removable by an appropriate number of focusing elements. The instrument uses the pepperpot method of introducing a plate with many pinholes into the beam and observing the images of the resulting beamlets as they interact with a detector after an appropriate drift distance. In order to produce adequate optical signal and repeatability, the detector was chosen to be a microchannel plate (MCP) with a phosphor readout screen. The heavy ions in the pepperpot beamlets are stopped in the MCP's thin front metal anode and the resulting secondary electron signal is amplified and proximity-focused onto the phosphor while maintaining the spatial and intensity characteristics of the heavy ion beamlets. The MCP used in this manner is a sensitive, accurate, and long-lasting detector, resistant against signal degradation experienced by previous methods of intense heavy ion beam detection and imaging. The performance of the GBI was benchmarked against existing mechanical emittance diagnostics and the results of sophisticated beam transport numerical simulation codes to demonstrate its usefulness as a diagnostic tool. A method of beam correction to remove the effects of quadrupole focusing element rotational misalignments is proposed using data obtainable from a GBI. An optimizing code was written to determine the parameters of the correction system elements based on input from the GBI. The results of this code for the Small Recirculator beam are reported on.« less

A simple high-performance matrix-free biomass molten carbonate fuel cell without CO2 recirculation

PubMed Central

Lan, Rong; Tao, Shanwen

2016-01-01

In previous reports, flowing CO2 at the cathode is essential for either conventional molten carbonate fuel cells (MCFCs) based on molten carbonate/LiAlO2 electrolytes or matrix-free MCFCs. For the first time, we demonstrate a high-performance matrix-free MCFC without CO2 recirculation. At 800°C, power densities of 430 and 410 mW/cm2 are achieved when biomass—bamboo charcoal and wood, respectively–is used as fuel. At 600°C, a stable performance is observed during the measured 90 hours after the initial degradation. In this MCFC, CO2 is produced at the anode when carbon-containing fuels are used. The produced CO2 then dissolves and diffuses to the cathode to react with oxygen in open air, forming the required CO32− or CO42− ions for continuous operation. The dissolved O2− ions may also take part in the cell reactions. This provides a simple new fuel cell technology to directly convert carbon-containing fuels such as carbon and biomass into electricity with high efficiency. PMID:27540588

A simple high-performance matrix-free biomass molten carbonate fuel cell without CO2 recirculation.

PubMed

Lan, Rong; Tao, Shanwen

2016-08-01

In previous reports, flowing CO2 at the cathode is essential for either conventional molten carbonate fuel cells (MCFCs) based on molten carbonate/LiAlO2 electrolytes or matrix-free MCFCs. For the first time, we demonstrate a high-performance matrix-free MCFC without CO2 recirculation. At 800°C, power densities of 430 and 410 mW/cm(2) are achieved when biomass-bamboo charcoal and wood, respectively-is used as fuel. At 600°C, a stable performance is observed during the measured 90 hours after the initial degradation. In this MCFC, CO2 is produced at the anode when carbon-containing fuels are used. The produced CO2 then dissolves and diffuses to the cathode to react with oxygen in open air, forming the required [Formula: see text] or [Formula: see text] ions for continuous operation. The dissolved [Formula: see text] ions may also take part in the cell reactions. This provides a simple new fuel cell technology to directly convert carbon-containing fuels such as carbon and biomass into electricity with high efficiency.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tsai, C. -Y.; Derbenev, Ya. S.; Douglas, D.

For a high-brightness electron beam with low energy and high bunch charge traversing a recirculation beamline, coherent synchrotron radiation and space charge effect may result in the microbunching instability (MBI). Both tracking simulation and Vlasov analysis for an early design of Circulator Cooler Ring for the Jefferson Lab Electron Ion Collider reveal significant MBI. It is envisioned these could be substantially suppressed by using a magnetized beam. In this work, we extend the existing Vlasov analysis, originally developed for a non-magnetized beam, to the description of transport of a magnetized beam including relevant collective effects. As a result, the newmore » formulation will be further employed to confirm prediction of microbunching suppression for a magnetized beam transport in a recirculating machine design.« less

Inductively generated streaming plasma ion source

DOEpatents

Glidden, Steven C.; Sanders, Howard D.; Greenly, John B.

2006-07-25

A novel pulsed, neutralized ion beam source is provided. The source uses pulsed inductive breakdown of neutral gas, and magnetic acceleration and control of the resulting plasma, to form a beam. The beam supplies ions for applications requiring excellent control of ion species, low remittance, high current density, and spatial uniformity.

UREA/ammonium ion removal system for the orbiting frog otolith experiment. [ion exchange resins for water treatment during space missions

NASA Technical Reports Server (NTRS)

Schulz, J. R.; Anselmi, R. T.

1976-01-01

The feasibility of using free urease enzyme and ANGC-101 ion exchange resin to remove urea and ammonium ion for space system waste water applications was studied. Specifically examined is the prevention of urea and ammonia toxicity in a 30-day Orbiting Frog Otolith (OFO) flight experiment. It is shown that free urease enzyme used in conjunction with ANGC-101 ion-exchange resin and pH control can control urea and amonium ion concentration in unbuffered recirculating water. In addition, the resin does not adversely effect the bullfrogs by lowering the concentration of cations below critical minimum levels. Further investigations on bioburden control, frog waste excretion on an OFO diet, a trade-off analysis of methods of automating the urea/ammonium ion removal system and fabrication and test of a semiautomated breadboard were recommended as continuing efforts. Photographs of test equipment and test animals are shown.

The Thermal Ion Dynamics Experiment and Plasma Source Instrument

NASA Technical Reports Server (NTRS)

Moore, T. E.; Chappell, C. R.; Chandler, M. O.; Fields, S. A.; Pollock, C. J.; Reasoner, D. L.; Young, D. T.; Burch, J. L.; Eaker, N.; Waite, J. H., Jr.;

Note: A pulsed laser ion source for linear induction accelerators

NASA Astrophysics Data System (ADS)

Zhang, H.; Zhang, K.; Shen, Y.; Jiang, X.; Dong, P.; Liu, Y.; Wang, Y.; Chen, D.; Pan, H.; Wang, W.; Jiang, W.; Long, J.; Xia, L.; Shi, J.; Zhang, L.; Deng, J.

2015-01-01

We have developed a high-current laser ion source for induction accelerators. A copper target was irradiated by a frequency-quadrupled Nd:YAG laser (266 nm) with relatively low intensities of 108 W/cm2. The laser-produced plasma supplied a large number of Cu+ ions (˜1012 ions/pulse) during several microseconds. Emission spectra of the plasma were observed and the calculated electron temperature was about 1 eV. An induction voltage adder extracted high-current ion beams over 0.5 A/cm2 from a plasma-prefilled gap. The normalized beam emittance measured by a pepper-pot method was smaller than 1 π mm mrad.

A feasibility study of a NBI photoneutralizer based on nonlinear gating laser recirculation

NASA Astrophysics Data System (ADS)

Fassina, A.; Pretato, F.; Barbisan, M.; Giudicotti, L.; Pasqualotto, R.

2016-02-01

The neutralization efficiency of negative ion neutral beam injectors is a major issue for future fusion reactors. Photon neutralization might be a valid alternative to present gas neutralizers, but still with several challenges for a valid implementation. Some concepts have been presented so far but none has been validated yet. A novel photoneutralization concept is discussed here, based on an annular cavity and a duplicated frequency laser beam (recirculation injection by nonlinear gating). The choice of lithium triborate as the material for the second harmonic extractor is discussed and a possible cooling method via crystal slicing is presented; laser intensity enhancement within the cavity is evaluated in order to quantify the achievable neutralization rate. Mockups of the critical components are proposed as intermediate steps toward system realization.

Vlasov analysis of microbunching instability for magnetized beams

DOE PAGES

Tsai, C. -Y.; Derbenev, Ya. S.; Douglas, D.; ...

2017-05-19

For a high-brightness electron beam with low energy and high bunch charge traversing a recirculation beamline, coherent synchrotron radiation and space charge effect may result in the microbunching instability (MBI). Both tracking simulation and Vlasov analysis for an early design of Circulator Cooler Ring for the Jefferson Lab Electron Ion Collider reveal significant MBI. It is envisioned these could be substantially suppressed by using a magnetized beam. In this work, we extend the existing Vlasov analysis, originally developed for a non-magnetized beam, to the description of transport of a magnetized beam including relevant collective effects. As a result, the newmore » formulation will be further employed to confirm prediction of microbunching suppression for a magnetized beam transport in a recirculating machine design.« less

HPRT mutations in V79 Chinese hamster cells induced by accelerated Ni, Au and Pb ions.

PubMed

Stoll, U; Barth, B; Scheerer, N; Schneider, E; Kiefer, J

1996-07-01

Mutation induction by accelerated heavy ions to 6-TG resistance (HPRT system) in V79 Chinese hamster cells was investigated with Ni (6-630 Me V/u), Au (2.2, 8.7 Me V/u) and Pb ions (11.6-980 Me V/u) corresponding to a LET range between 180 and 12895 ke V/microns. Most experiments could only be performed once due to technical limitations using accelerator beam times. Survival curves were exponential, mutation induction curves linear with fluence. From their slopes inactivation- and mutation-induction cross-sections were derived. If they are plotted versus LET, single, ion-specific curves are obtained. It is shown that other parameters like ion energy and effective charge play an important role. In the case of Au and Pb ions the cross-sections follow a common line, since these ions have nearly the same atomic weight, so that they should have similar spatial ionization patterns in matter at the same energies. Calculated RBEs were higher for mutation induction than for killing for all LETs.

Note: A pulsed laser ion source for linear induction accelerators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, H., E-mail: bamboobbu@hotmail.com; School of Physics, Peking University, Beijing 100871; Zhang, K.

2015-01-15

We have developed a high-current laser ion source for induction accelerators. A copper target was irradiated by a frequency-quadrupled Nd:YAG laser (266 nm) with relatively low intensities of 10{sup 8} W/cm{sup 2}. The laser-produced plasma supplied a large number of Cu{sup +} ions (∼10{sup 12} ions/pulse) during several microseconds. Emission spectra of the plasma were observed and the calculated electron temperature was about 1 eV. An induction voltage adder extracted high-current ion beams over 0.5 A/cm{sup 2} from a plasma-prefilled gap. The normalized beam emittance measured by a pepper-pot method was smaller than 1 π mm mrad.

Ultrafast harmonic rf kicker design and beam dynamics analysis for an energy recovery linac based electron circulator cooler ring

DOE PAGES

Huang, Yulu; Wang, Haipeng; Rimmer, Robert A.; ...

2016-08-01

An ultrafast kicker system is being developed for the energy recovery linac (ERL) based electron circulator cooler ring (CCR) in the proposed Jefferson Lab Electron Ion Collider (JLEIC, previously named MEIC). In the CCR, the injected electron bunches can be recirculated while performing ion cooling for 10–30 turns before the extraction, thus reducing the recirculation beam current in the ERL to 1/10–1/30 (150mA–50 mA) of the cooling beam current (up to 1.5 A). Assuming a bunch repetition rate of 476.3 MHz and a recirculating factor of 10 in the CCR, the kicker is required to operate at a pulse repetitionmore » rate of 47.63 MHz with pulse width of around 2 ns, so that only every 10th bunch in the CCR will experience a transverse kick while the rest of the bunches will not be disturbed. Such a kicker pulse can be synthesized by ten harmonic modes of the 47.63 MHz kicker pulse repetition frequency, using up to four quarter wavelength resonator (QWR) based deflecting cavities. In this paper, several methods to synthesize such a kicker waveform will be discussed and a comparison of their beam dynamics performance is made using ELEGANT. Four QWR cavities are envisaged with high transverse shunt impedance requiring less than 100 W of total rf power for a Flat-Top kick pulse. Multipole fields due to the asymmetry of this type of cavity are analyzed. The transverse emittance growth due to the sextupole component is simulated in ELEGANT. In conclusion, off-axis injection and extraction issues and beam optics using a multicavity kick-drift scheme will also be discussed.« less

Ultrafast harmonic rf kicker design and beam dynamics analysis for an energy recovery linac based electron circulator cooler ring

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, Yulu; Wang, Haipeng; Rimmer, Robert A.

An ultrafast kicker system is being developed for the energy recovery linac (ERL) based electron circulator cooler ring (CCR) in the proposed Jefferson Lab Electron Ion Collider (JLEIC, previously named MEIC). In the CCR, the injected electron bunches can be recirculated while performing ion cooling for 10–30 turns before the extraction, thus reducing the recirculation beam current in the ERL to 1/10–1/30 (150mA–50 mA) of the cooling beam current (up to 1.5 A). Assuming a bunch repetition rate of 476.3 MHz and a recirculating factor of 10 in the CCR, the kicker is required to operate at a pulse repetitionmore » rate of 47.63 MHz with pulse width of around 2 ns, so that only every 10th bunch in the CCR will experience a transverse kick while the rest of the bunches will not be disturbed. Such a kicker pulse can be synthesized by ten harmonic modes of the 47.63 MHz kicker pulse repetition frequency, using up to four quarter wavelength resonator (QWR) based deflecting cavities. In this paper, several methods to synthesize such a kicker waveform will be discussed and a comparison of their beam dynamics performance is made using ELEGANT. Four QWR cavities are envisaged with high transverse shunt impedance requiring less than 100 W of total rf power for a Flat-Top kick pulse. Multipole fields due to the asymmetry of this type of cavity are analyzed. The transverse emittance growth due to the sextupole component is simulated in ELEGANT. In conclusion, off-axis injection and extraction issues and beam optics using a multicavity kick-drift scheme will also be discussed.« less

Ion sampling and transport in Inductively Coupled Plasma Mass Spectrometry

NASA Astrophysics Data System (ADS)

Farnsworth, Paul B.; Spencer, Ross L.

2017-08-01

Quantitative accuracy and high sensitivity in inductively coupled plasma mass spectrometry (ICP-MS) depend on consistent and efficient extraction and transport of analyte ions from an inductively coupled plasma to a mass analyzer, where they are sorted and detected. In this review we examine the fundamental physical processes that control ion sampling and transport in ICP-MS and compare the results of theory and computerized models with experimental efforts to characterize the flow of ions through plasma mass spectrometers' vacuum interfaces. We trace the flow of ions from their generation in the plasma, into the sampling cone, through the supersonic expansion in the first vacuum stage, through the skimmer, and into the ion optics that deliver the ions to the mass analyzer. At each stage we consider idealized behavior and departures from ideal behavior that affect the performance of ICP-MS as an analytical tool.

Multicharged iron ions produced by using induction heating vapor source.

PubMed

Kato, Yushi; Kubo, Takashi; Muramatsu, Masayuki; Tanaka, Kiyokatsu; Kitagawa, Atsushi; Yoshida, Yoshikazu; Asaji, Toyohisa; Sato, Fuminobu; Iida, Toshiyuki

2008-02-01

Multiply charged Fe ions are produced from solid pure material in an electron cyclotron resonance (ECR) ion source. We develop an evaporator by using induction heating with an induction coil which is made of bare molybdenum wire partially covered by ceramic beads in vacuum and surrounding and heating directly the pure Fe rod. Heated material has no contact with insulators, so that outgas is minimized. The evaporator is installed around the mirror end plate outside of the ECR plasma with its hole grazing the ECR zone. Helium or argon gas is usually chosen for supporting gas. The multicharged Fe ions up to Fe(13+) are extracted from the opposite side of mirror and against the evaporator, and then multicharged Fe ion beam is formed. We compare production of multicharged iron ions by using this new source with our previous methods.

Mutation induction in bacteria after heavy ion irradiation

NASA Technical Reports Server (NTRS)

Horneck, G.; Kozubek, S.

1994-01-01

From a compilation of experimental data on the mutagenic effects of heavy ions in bacteria, main conclusions have been drawn as follows: (1) The mutagenic efficacy of heavy ions in bacteria depends on physical and biological variables. Physical variables are the radiation dose, energy and charge of the ion; the biological variables are the bacterial strain, the repair genotype of bacteria, and the endpoint investigated (type of mutation, induction of enzymes related to mutagenesis); (2) The responses on dose or fluence are mainly linear or linear quadratic. The quadratic component, if found for low LET radiation, is gradually reduced with increasing LET; (3) At low values of Z and LET the cross section of mutation induction sigma m (as well as SOS response, sigma sos. and lambda phage induction, sigma lambda versus LET curves can be quite consistently described by a common function which increases up to approximately 100 keV/mu m. For higher LET values, the sigma(m) versus LET curves show the so-called 'hooks' observed also for other endpoints; (4) For light ions (Z is less than or equal to 4), the cross sections mostly decrease with increasing ion energy, which is probably related to the decrease of the specific energy departed by the ion inside the sensitive volume (cell). For ions in the range of Z = 10, sigma(m) is nearly independent on the ion energy. For heavier ions (Z is greater than or equal to 16), sigma(m) increases with the energy up to a maximum or saturation around 10 MeV/u. The increment becomes steeper with increasing atomic number of the ion. It correlates with the increasing track radius of the heavy ion; (5) The mutagenic efficiency per lethal event changes slightly with ion energy, if Z is small indicating a rough correlation between cellular lethality and mutation induction, only. For ions of higher Z this relation increases with energy, indicating a change in the 'mode' of radiation action from 'killing-prone' to 'mutation-prone'; and (6) Repair genotype substantially influences the radiation induced mutagenesis. Different mechanisms of mutation induction and/or different types of biologically significant lesions in wild type cells compared to repair deficient strains are a likely explanation.

Impact of inlet coherent motions on compressor performance

NASA Astrophysics Data System (ADS)

Forlese, Jacopo; Spoleti, Giovanni

2017-08-01

Automotive engine induction systems may be characterized by significant flow angularity and total pressure distortion at the compressor inlet. The impact of the swirl on compressor performance should be quantified to guide the design of the induction systems. In diesel engines, the presence of a valve for flow reduction and control of low pressure EGR recirculation could generate coherent motion and influence the performance of the compressor. Starting from experimental map, the compressor speed-lines have been simulated using a 3D CFD commercial code imposing different concept motion at the inlet. The swirl intensity, the direction and the number of vortices have been imposed in order to taking into account some combinations. Finally, a merit function has been defined to evaluate the performance of the compressor with the defined swirl concepts. The aim of the current work is to obtain an indication on the effect of a swirling motion at the compressor inlet on the engine performance and provide a guideline to the induction system design.

Pure Material Vapor Source by Induction Heating Evaporator for an Electron Cyclotron Resonance Ion Source

NASA Astrophysics Data System (ADS)

Matsui, Y.; Watanabe, T.; Satani, T.; Muramatsu, M.; Tanaka, K.; Kitagawa, A.; Yoshida, Y.; Sato, F.; Kato, Y.; Iida, T.

2008-11-01

Multiply charged iron ions are produced from solid pure material in an electron cyclotron resonance (ECR) ion source. We develop an evaporator by using induction heating with the induction coil which is made from bare molybdenum wire and surrounding the pure iron rod. We optimize the shape of induction heating coil and operation of rf power supply. We conduct experiment to investigate reproducibility and stability in the operation and heating efficiency. Induction heating evaporator produces pure material vapor, because materials directly heated by eddy currents have non-contact with insulated materials which are impurity gas sources. The power and the frequency of the induction currents range from 100 to 900 W and from 48 to 23 kHz, respectively. The working pressure is about 10-4 to 10-3 Pa. We measure temperature of iron rod and film deposition rate by depositing iron vapor to crystal oscillator. We confirm stability and reproducibility of evaporator enough to conduct experiment in ECR ion source. We can obtain required temperature of iron under maximum power of power supply. We are aiming the evaporator higher melting point material than iron.

Multiple beam induction accelerators for heavy ion fusion

NASA Astrophysics Data System (ADS)

Seidl, Peter A.; Barnard, John J.; Faltens, Andris; Friedman, Alex; Waldron, William L.

2014-01-01

Induction accelerators are appealing for heavy-ion driven inertial fusion energy (HIF) because of their high efficiency and their demonstrated capability to accelerate high beam current (≥10 kA in some applications). For the HIF application, accomplishments and challenges are summarized. HIF research and development has demonstrated the production of single ion beams with the required emittance, current, and energy suitable for injection into an induction linear accelerator. Driver scale beams have been transported in quadrupole channels of the order of 10% of the number of quadrupoles of a driver. We review the design and operation of induction accelerators and the relevant aspects of their use as drivers for HIF. We describe intermediate research steps that would provide the basis for a heavy-ion research facility capable of heating matter to fusion relevant temperatures and densities, and also to test and demonstrate an accelerator architecture that scales well to a fusion power plant.

Mutation induction in yeast by very heavy ions

NASA Astrophysics Data System (ADS)

Kiefer, J.

1994-10-01

Resistance to canavanine was studied in haploid yeast after exposure to heavy ions (argon to uranium) of energies between 1 and 10 MeV/u covering a LET-range up to about 10000 keV/μm. Mutations were found in all instances but the induction cross sections increased with ion energy. This is taken to mean that the contribution of penumbra electrons plays an important role. The probability to recover surviving mutants is highest if the cell is not directly hit by the particle. The experiments demonstrate that the geometrical dimensions of the target cell nucleus as well as its sensitivity in terms of survival have a critical influence on mutation induction with very heavy ions.

Energy gain calculations in Penning fusion systems using a bounce-averaged Fokker-Planck model

NASA Astrophysics Data System (ADS)

Chacón, L.; Miley, G. H.; Barnes, D. C.; Knoll, D. A.

2000-11-01

In spherical Penning fusion devices, a spherical cloud of electrons, confined in a Penning-like trap, creates the ion-confining electrostatic well. Fusion energy gains for these systems have been calculated in optimistic conditions (i.e., spherically uniform electrostatic well, no collisional ion-electron interactions, single ion species) using a bounce-averaged Fokker-Planck (BAFP) model. Results show that steady-state distributions in which the Maxwellian ion population is dominant correspond to lowest ion recirculation powers (and hence highest fusion energy gains). It is also shown that realistic parabolic-like wells result in better energy gains than square wells, particularly at large well depths (>100 kV). Operating regimes with fusion power to ion input power ratios (Q-value) >100 have been identified. The effect of electron losses on the Q-value has been addressed heuristically using a semianalytic model, indicating that large Q-values are still possible provided that electron particle losses are kept small and well depths are large.

Beam dynamics in heavy ion induction LINACS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, L.

1981-10-01

Interest in the use of an induction linac to accelerate heavy ions for the purpose of providing the energy required to initiate an inertially confined fusion reaction has stimulated a theoretical effort to investigate various beam dynamical effects associated with high intensity heavy ion beams. This paper presents a summary of the work that has been done so far; transverse, longitudinal and coupled longitudinal transverse effects are discussed.

Atomic-scale thermocapillary flow in focused ion beam milling

NASA Astrophysics Data System (ADS)

Das, Kallol; Johnson, Harley; Freund, Jonathan

2016-11-01

Focused ion beams (FIB) offer an attractive tool for nanometer-scale manufacturing and material processing, particularly because they can be focused to a few nanometer diameter spot. This motivates their use for many applications, such as sample preparation for transmission electron microscopy (TEM), forming nanometer scale pores in thin films for DNA sequencing. Despite its widespread use, the specific mechanisms of FIB milling, especially at high ion fluxes for which significant phase change might occur, remains incompletely understood. Here we investigate the process of nanopore fabrication in thin Si films using molecular dynamics simulation where Ga+ ions are used as the focused ions. For a range of ion intensities in a realistic configuration, a recirculating melt region develops, which is seen to flow with a symmetrical pattern, counter to how it would flow were it is driven by the ion momentum flux. Such flow is potentially important for the shape and composition of the formed structures. Relevant stress scales and estimated physical properties of silicon under these extreme conditions support the importance thermocapillary effects. A continuum flow model with Marangoni forcing reproduces the flow.

LET and ion-species dependence for mutation induction and mutation spectrum on hprt locus in normal human fibroblasts.

PubMed

Tsuruoka, Chizuru; Suzuki, Masao; Fujitaka, Kazunobu

2004-11-01

We have been studying LET and ion species dependence of RBE in mutation frequency and mutation spectrum of deletion pattern of exons in hprt locus. Normal human skin fibroblasts were irradiated with heavy-ion beams, such as carbon- (290 MeV/u and 135 MeV/u), neon- (230 MeV/u and 400 MeV/u), silicon- (490 MeV/u) and iron- (500 MeV/u) ion beams, generated by Heavy Ion Medical Accelerator in Chiba (HIMAC) at national Institute of Radiological Sciences (NIRS). Mutation induction in hprt locus was detected to measure 6-thioguanine resistant colonies and deletion spectrum of exons was analyzed by multiplex PCR. The LET-RBE curves of mutation induction for carbon- and neon-ion beams showed a peak around 75 keV/micrometers and 155 keV/micrometers, respectively. On the other hand, there observed no clear peak for silicon-ion beams. The deletion spectrum of exons was different in induced mutants among different ion species. These results suggested that quantitative and qualitative difference in mutation occurred when using different ion species even if similar LET values.

Spherical ion oscillations in a positive polarity gridded inertial-electrostatic confinement device

NASA Astrophysics Data System (ADS)

Bandara, R.; Khachan, J.

2013-07-01

A pulsed, positive polarity gridded inertial electrostatic confinement device has been investigated experimentally, using a differential emissive probe and potential traces as primary diagnostics. Large amplitude oscillations in the plasma current and plasma potential were observed within a microsecond of the discharge onset, which are indicative of coherent ion oscillations about a temporarily confined excess of recirculating electron space charge. The magnitude of the depth of the potential well in the established virtual cathode was determined using a differential emissive Langmuir probe, which correlated well to the potential well inferred from the ion oscillation frequency for both hydrogen and argon experiments. It was found that the timescale for ion oscillation dispersion is strongly dependent on the neutral gas density, and weakly dependent on the peak anode voltage. The cessation of the oscillations was found to be due to charge exchange processes converting ions to high velocity neutrals, causing the abrupt de-coherence of the oscillations through an avalanche dispersion in phase space.

Correlation between cell death and induction of non-rejoining PCC breaks by carbon-ion beams.

PubMed

Suzuki, M; Kase, Y; Kanai, T; Ando, K

1998-01-01

We have shown a correlation between cell death and induction of non-rejoining chromatin breaks in two normal human cells and three human tumor cell lines irradiated by carbon-ion beams and X rays. Non-rejoining chromatin breaks were measured by counting the number of remaining chromatin fragments detected by the premature chromosome condensation (PCC) technique. Carbon-ion beams were accelerated by the Heavy Ion Medical Accelerator in Chiba (HIMAC). The cells were irradiated by two different mono-LET beams (LET = 13 keV/micrometer and 77 keV/micrometer ) and 200 kV X rays. The RBE values of cell death for carbon-ion beams relative to X rays were 1.1 to 1.4 for 13 keV/micrometer beams and 2.5 to 2.9 for 77 keV/micrometer beams. The induction rate of non-rejoining PCC breaks per cell per Gy was found to be highest for the 77 keV/micrometer beams for all of the cell lines. The results found in this study show that there is a good correlation between cell death and induction of non-rejoining PCC breaks for these human cell lines.

DETERMINATION OF BROMATE IN DRINKING WATERS BY ION CHROMATOGRAPHY WITH INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRIC DETECTION

EPA Science Inventory

Bromate is a disinfection by-product in drinking water, formed during the ozonation of source water containing bromide. An inductively coupled plasma mass spectrometer is combined with an ion chromatograph for the analysis of bromate in drinking waters. Three chromatographic colu...

ISOTOPE DILUTION ANALYSIS OF BROMATE IN DRINKING WATER MATRIXES BY ION CHROMATOGRAPHY WITH INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRIC DETECTION

EPA Science Inventory

Bromate is a disinfection byproduct in drinking water which is formed during the ozonation of source water containing bromide. This paper described the analysis of bromate via ion chromatography-inductively coupled plasma mass spectrometry. The separation of bromate from interfer...

Liquid-metal flows: Magnetohydrodynamics and applications; Proceedings of the Fifth Beersheba International Seminar on Magnetohydrodynamic Flows and Turbulence, University of the Negev, Beersheba, Israel, Mar. 2-6, 1987

DOE Office of Scientific and Technical Information (OSTI.GOV)

Branover, H.; Mond, M.; Unger, Y.

The present collection of papers on MHD-related uses of liquid metal flows and their applications discusses topics in laminar MHD flows, MHD power generation, metallurgical MHD applications, and two-phase MHD flows. Attention is given to MHD flows with closed streamlines, nonlinear waves in liquid metals under a transverse magnetic field, liquid-metal MHD conversion of nuclear energy to electricity, the testing of optimized MHD conversion (OMACON) systems, and aspects of a liquid-metal induction generator. Also discussed are MHD effects in liquid-metal breeder reactors, a plasma-driven MHD powerplant, modeling the recirculating flows in channel-induction surfaces, the hydrodynamics of aluminum reduction cells, free-surfacemore » determination in a levitation-melting process, the parametric interactions of waves in bubbly liquid metals, and the occurrence of cavitation in water jets.« less

Status of the University of Rochester tandem upgrade

NASA Astrophysics Data System (ADS)

Cross, Clinton; Miller, Thomas

1986-05-01

The status of the University of Rochester tandem Van de Graaff accelerator upgrade is reviewed. The accelerator upgrade to 18 MV consists of extended tubes, shielded resistors, dead-section ion pumping, two rotating insulating power shaft systems to provide power to the dead sections and terminal, and a pelletron charging system to replace the charging belt. Control of many of the accelerator operating systems will be done by two IBM personal computers. The negative ion injector diffusion pump, isolation transformer, preacceleration high-voltage power supply, and high-voltage corona enclosure will all be replaced. Finally, the SF6 gas handling system will be improved with the addition of a second set of gas dryers and a larger recirculating pump.

Predictions of ion energy distributions and radical fluxes in radio frequency biased inductively coupled plasma etching reactors

NASA Astrophysics Data System (ADS)

Hoekstra, Robert J.; Kushner, Mark J.

1996-03-01

Inductively coupled plasma (ICP) reactors are being developed for low gas pressure (<10s mTorr) and high plasma density ([e]≳1011 cm-3) microelectronics fabrication. In these reactors, the plasma is generated by the inductively coupled electric field while an additional radio frequency (rf) bias is applied to the substrate. One of the goals of these systems is to independently control the magnitude of the ion flux by the inductively coupled power deposition, and the acceleration of ions into the substrate by the rf bias. In high plasma density reactors the width of the sheath above the wafer may be sufficiently thin that ions are able to traverse it in approximately 1 rf cycle, even at 13.56 MHz. As a consequence, the ion energy distribution (IED) may have a shape typically associated with lower frequency operation in conventional reactive ion etching tools. In this paper, we present results from a computer model for the IED incident on the wafer in ICP etching reactors. We find that in the parameter space of interest, the shape of the IED depends both on the amplitude of the rf bias and on the ICP power. The former quantity determines the average energy of the IED. The latter quantity controls the width of the sheath, the transit time of ions across the sheath and hence the width of the IED. In general, high ICP powers (thinner sheaths) produce wider IEDs.

Chromosomal instability induced by heavy ion irradiation

NASA Technical Reports Server (NTRS)

Limoli, C. L.; Ponnaiya, B.; Corcoran, J. J.; Giedzinski, E.; Morgan, W. F.

2000-01-01

PURPOSE: To establish the dose-response relationship for the induction of chromosomal instability in GM10115 cells exposed to high-energy iron ions (1 GeV/nucleon, mean LET 146 keV/microm) and gold ions (11 GeV/nucleon, mean LET 1450 keV/microm). Past work has established that sparsely ionizing X-rays can induce a long-lived destabilization of chromosomes in a dose-dependent manner at an incidence of approximately 3% per gray. The present investigation assesses the capacity of High-Z and High-energy (HZE) particles to elicit this same endpoint. MATERIALS AND METHODS: Clonal populations derived from single progenitor cells surviving heavy-ion irradiation were analyzed cytogenetically to identify those clones showing a persistent destablization of chromosomes. RESULTS: Dose-response data, with a particular emphasis at low dose (< 1.0 Gy), indicate a frequency of approximately 4% per gray for the induction of chromosomal instability in clones derived from single progenitor cells surviving exposure to iron ions. The induction of chromosomal instability by gold ions was, however, less responsive to applied dose, as the observed incidence of this phenotype varied from 0 to 10% over 1-8 Gy. Both iron and gold ions gave dose-dependent increases in the yield of chromosomal aberrations (both chromosome- and chromatid-type) measured at the first mitosis following irradiation, as well as shoulderless survival curves having D0=0.87 and 1.1 Gy respectively. CONCLUSIONS: Based on the present dose-response data, the relative biological effectiveness of iron ions is 1.3 for the induction of chromosomal instability, and this indicates that heavy ions are only slightly more efficient than X-rays at eliciting this delayed phenotype.

The kinetics, current efficiency, and power consumption of electrochemical dye decolorization by BD-NCD film electrode

NASA Astrophysics Data System (ADS)

Nurhayati, Ervin; Juang, Yaju; Huang, Chihpin

2017-06-01

Diamond film electrode has been known as a material with very wide potential window for water electrolysis which leads to its applicability in numerous electrochemical processes. Its capability to produce hydroxyl radicals, a very strong oxidants, prompts its popular application in wastewater treatment. Batch and batch recirculation reactor were applied to perform bulk electrolysis experiments to investigate the kinetics of dye decolorization under different operation conditions, such as pH, active species, and current density. Furthermore, COD degradation data from batch recirculation reactor operation was used as the basis for the calculation of current efficiency and power consumption in the decolorization process. The kinetics of decolorization process using boron-doped nanocrystalline diamond (BD-NCD) film electrode revealed that acidic condition is favored for the dye degradation, and the presence of chloride ion in the solution was found to be more advantageous than sulfate active species, as evidenced by the higher reaction rate constants. Applying different current density of 10, 20 and 30 mA cm-2, it was found that the higher the current density the faster the decolorization rate. General current efficiency achieved after nearly total decolorization and 80% COD removal in batch recirculation reactor was around 74%, with specific power consumption of 4.4 kWh m-3 (in terms of volume of solution treated) or 145 kWh kg-1(in terms of kg COD treated).

Measurements and effects of backstreaming ions produced at bremsstrahlung converter target in Dragon-I linear induction accelerator.

PubMed

Yu, Haijun; Zhu, Jun; Chen, Nan; Xie, Yutong; Jiang, Xiaoguo; Jian, Cheng

2010-04-01

Positive ions released from x-ray converter target impacted by electron beam of millimeter spot size can be trapped and accelerated in the incident beam's potential well. As the ions move upstream, the beam will be pinched first and then defocused at the target. Four Faraday cups are used to collect backstreaming ions produced at the bremsstrahlung converter target in Dragon-I linear induction accelerator (LIA). Experimental and theoretical results show that the backstreaming positive ions density and velocity are about 10(21)/m(3) and 2-3 mm/micros, respectively. The theoretical and experimental results of electron beam envelope with ions and without ions are also presented. The discussions show that the backstreaming positive ions will not affect the electron beam focusing and envelope radius in Dragon-I LIA.

Measurements and effects of backstreaming ions produced at bremsstrahlung converter target in Dragon-I linear induction accelerator

NASA Astrophysics Data System (ADS)

Yu, Haijun; Zhu, Jun; Chen, Nan; Xie, Yutong; Jiang, Xiaoguo; Jian, Cheng

2010-04-01

Positive ions released from x-ray converter target impacted by electron beam of millimeter spot size can be trapped and accelerated in the incident beam's potential well. As the ions move upstream, the beam will be pinched first and then defocused at the target. Four Faraday cups are used to collect backstreaming ions produced at the bremsstrahlung converter target in Dragon-I linear induction accelerator (LIA). Experimental and theoretical results show that the backstreaming positive ions density and velocity are about 1021/m3 and 2-3 mm/μs, respectively. The theoretical and experimental results of electron beam envelope with ions and without ions are also presented. The discussions show that the backstreaming positive ions will not affect the electron beam focusing and envelope radius in Dragon-I LIA.

Recirculation of reverse osmosis concentrate in lab-scale anaerobic and aerobic landfill simulation reactors.

PubMed

Morello, Luca; Cossu, Raffaello; Raga, Roberto; Pivato, Alberto; Lavagnolo, Maria Cristina

2016-10-01

Leachate treatment is a major issue in the context of landfill management, particularly in view of the consistent changes manifested over time in the quality and quantity of leachate produced, linked to both waste and landfill characteristics, which renders the procedure technically difficult and expensive. Leachate recirculation may afford a series of potential advantages, including improvement of leachate quality, enhancement of gas production, acceleration of biochemical processes, control of moisture content, as well as nutrients and microbe migration within the landfill. Recirculation of the products of leachate treatment, such as reverse osmosis (RO) concentrate, is a less common practice, with widespread controversy relating to its suitability, potential impacts on landfill management and future gaseous and leachable emissions. Scientific literature provides the results of only a few full-scale applications of concentrate recirculation. In some cases, an increase of COD and ammonium nitrogen in leachate was observed, coupled with an increase of salinity; which, additionally, might negatively affect performance of the RO plant itself. In other cases, not only did leachate production not increase significantly but the characteristics of leachate extracted from the well closest to the re-injection point also remained unchanged. This paper presents the results of lab-scale tests conducted in landfill simulation reactors, in which the effects of injection of municipal solid waste (MSW) landfill leachate RO concentrate were evaluated. Six reactors were managed with different weekly concentrate inputs, under both anaerobic and aerobic conditions, with the aim of investigating the short and long-term effects of this practice on landfill emissions. Lab-scale tests resulted in a more reliable identification of compound accumulation and kinetic changes than full-scale applications, further enhancing the development of a mass balance in which gaseous emissions and waste characteristics were also taken into consideration. Results showed that RO concentrate recirculation did not produce consistent changes in COD emissions and methane production. Simultaneously, ammonium ion showed a consistent increase in leachate (more than 25%) in anaerobic reactors, free ammonia gaseous emissions doubled with concentrate injection, while chloride resulted accumulated inside the reactor. Copyright © 2016 Elsevier Ltd. All rights reserved.

Acceleration and stability of a high-current ion beam in induction fields

NASA Astrophysics Data System (ADS)

Karas', V. I.; Manuilenko, O. V.; Tarakanov, V. P.; Federovskaya, O. V.

2013-03-01

A one-dimensional nonlinear analytic theory of the filamentation instability of a high-current ion beam is formulated. The results of 2.5-dimensional numerical particle-in-cell simulations of acceleration and stability of an annular compensated ion beam (CIB) in a linear induction particle accelerator are presented. It is shown that additional transverse injection of electron beams in magnetically insulated gaps (cusps) improves the quality of the ion-beam distribution function and provides uniform beam acceleration along the accelerator. The CIB filamentation instability in both the presence and the absence of an external magnetic field is considered.

Ion collector design for an energy recovery test proposal with the negative ion source NIO1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Variale, V., E-mail: vincenzo.variale@ba.infn.it; Cavenago, M.; Agostinetti, P.

2016-02-15

Commercial viability of thermonuclear fusion power plants depends also on minimizing the recirculation power used to operate the reactor. The neutral beam injector (NBI) remains one of the most important method for plasma heating and control. For the future fusion power plant project DEMO, a NBI wall plug efficiency at least of 0.45 is required, while efficiency of present NBI project is about 0.25. The D{sup −} beam from a negative ion source is partially neutralized by a gas cell, which leaves more than 40% of energy in residual beams (D{sup −} and D{sup +}), so that an ion beammore » energy recovery system can significantly contribute to optimize efficiency. Recently, the test negative ion source NIO1 (60 keV, 9 beamlets with 15 mA H{sup −} each) has been designed and built at RFX (Padua) for negative ion production efficiency and the beam quality optimization. In this paper, a study proposal to use the NIO1 source also for a beam energy recovery test experiment is presented and a preliminary design of a negative ion beam collector with simulations of beam energy recovery is discussed.« less

Induction of anchorage-independent growth in primary human cells exposed to protons or HZE ions separately or in dual exposures.

PubMed

Sutherland, B M; Cuomo, N C; Bennett, P V

2005-10-01

Travelers on space missions will be exposed to a complex radiation environment that includes protons and heavy charged particles. Since protons are present at much higher levels than are heavy ions, the most likely scenario for cellular radiation exposure will be proton exposure followed by a hit by a heavy ion. Although the effects of individual ion species on human cells are being investigated extensively, little is known about the effects of exposure to both radiation types. One useful measure of mammalian cell damage is induction of the ability to grow in a semi-solid agar medium highly inhibitory to the growth of normal human cells, termed neoplastic transformation. Using primary human cells, we evaluated induction of soft-agar growth and survival of cells exposed to protons only or to heavy charged particles (600 MeV/nucleon silicon) only as well as of cells exposed to protons followed after a 4-day interval by silicon ions. Both ions alone efficiently transformed the human cells to anchorage-independent growth. Initial experiments indicate that the dose responses for neoplastic transformation of cells exposed to protons and then after 4 days to silicon ions appear similar to that of cells exposed to silicon ions alone.

Mass Spectrometric and Langmuir Probe Measurements in Inductively Coupled Plasmas in Ar, CHF3/Ar and CHF3/Ar/O2 Mixtures

NASA Technical Reports Server (NTRS)

Kim, J. S.; Rao, M. V. V. S.; Cappelli, M. A.; Sharma, S. P.; Meyyappan, M.; Arnold, Jim (Technical Monitor)

2000-01-01

Absolute fluxes and energy distributions of ions in inductively coupled plasmas of Ar, CHF3/Ar, and CHF3/Ar/O2 have been measured. These plasmas were generated in a Gaseous Electronics Conference (GEC) cell modified for inductive coupling at pressures 10-50 mTorr and 100-300 W of 13.56 MHz radio frequency (RF) power in various feedgas mixtures. In pure Ar plasmas, the Ar(+) flux increases linearly with pressure as well as RF-power. Total ion flux in CHF3 mixtures decreases with increase in pressure and also CHF3 concentration. Relative ion fluxes observed in the present studies are analyzed with the help of available cross sections for electron impact ionization and charge-exchange ion-molecule reactions. Measurements of plasma potential, electron and ion number densities, electron energy distribution function, and mean electron energy have also been made in the center of the plasma with a RF compensated Langmuir probe. Plasma potential values are compared with the mean ion energies determined from the measured ion energy distributions and are consistent. Electron temperature, plasma potential, and mean ion energy vary inversely with pressure, but increase with CHF3 content in the mixture.

DNA damage on nano- and micrometer scales impacts dicentric induction: computer modelling of ion microbeam experiments

NASA Astrophysics Data System (ADS)

Friedland, Werner; Kundrat, Pavel; Schmitt, Elke

2016-07-01

Detailed understanding of the enhanced relative biological effectiveness (RBE) of ions, in particular at high linear energy transfer (LET) values, is needed to fully explore the radiation risk of manned space missions. It is generally accepted that the enhanced RBE of high-LET particles results from the DNA lesion patterns, in particular DNA double-strand breaks (DSB), due to the spatial clustering of energy deposits around their trajectories. In conventional experiments on biological effects of radiation types of diverse quality, however, clustering of energy deposition events on nanometer scale that is relevant for the induction and local complexity of DSB is inherently interlinked with regional (sub-)micrometer-scale DSB clustering along the particle tracks. Due to this limitation, the role of both (nano- and micrometer) scales on the induction of diverse biological endpoints cannot be frankly separated. To address this issue in a unique way, experiments at the ion microbeam SNAKE [1] and corresponding track-structure based model calculations of DSB induction and subsequent repair with the biophysical code PARTRAC [2] have been performed. In the experiments, hybrid human-hamster A_{L} cells were irradiated with 20 MeV (2.6 keV/μm) protons, 45 MeV (60 keV/μm) lithium ions or 55 MeV (310 keV/μm) carbon ions. The ions were either quasi-homogeneously distributed or focused to 0.5 x 1 μm^{2} spots on regular matrix patterns of 5.4 μm, 7.6 μm and 10.6 μm grid size, with pre-defined particle numbers per spot so as to deposit a mean dose of 1.7 Gy for all irradiation patterns. As expected, the induction of dicentrics by homogeneous irradiation increased with LET: lithium and carbon ions induced about two- and four-fold higher yields of dicentrics than protons. The induction of dicentrics is, however, affected by µm-scale, too: focusing 20 lithium ions or 451 protons per spot on a 10.6 μm grid induced two or three times more dicentrics, respectively, than a quasi-homogenous irradiation with these particles [3]. PARTRAC calculations of initial DNA damage showed that the sub-micrometer beam focusing of the ions in these experiments affects neither DSB yields nor local DSB complexity, but considerably enhances the formation of DSB fragments of 10 - 1000 kbp size [4], corresponding to DSB pairs in about 100 - 500 nm distance. Thus, the substantial impact of ion focusing on dicentric induction points out that nanoscale DNA damage clustering can explain only partly the increased RBE of high LET radiation regarding dicentric induction. The measured trends for dicentric induction as a function of grid size (or particle number per spot) were largely reproduced by the calculated induction of total chromosomal aberrations, whereas the calculation of dicentrics yielded apparent discrepancies, such as an overestimation of the focusing effect for protons and of the yield for quasi-homogeneous lithium ions [3]. Since this incongruity was found to be rather robust against model parameter variations, a more basic review of the chromosomal aberration model with in-depth testing of several hypotheses on the origin of misrejoining events of DNA ends has been started considering the reported experimental findings. The results of ongoing parameter studies will be presented at the meeting. Acknowledgement. This work was supported by the German Federal Ministry of Education and Research (Project 'LET-Verbund', Funding no. 02NUK031C). References [1] Schmid et al. 2012 Phys. Med. Biol. 57, 5889-5907 [2] Friedland et al. 2011 Mutat. Res. 711, 28-40 [3] Schmid et al. 2015 Mutat. Res. 793, 30-40 [4] Friedland et al. 2015 Radiat. Prot. Dosim. 166, 34-37

Effects of heavy ions on inactivation and DNA double strand breaks in Deinococcus radiodurans R1.

PubMed

Zimmermann, H; Schafer, M; Schmitz, C; Bucker, H

1994-10-01

Inactivation and double strand break (dsb) induction after heavy ion irradiation were studied in stationary phase cells of the highly radiation resistant bacterium Deinococcus radiodurans R1. There is evidence that the radiation sensitivity of this bacterium is nearly independent on energy in the range of up to 15 MeV/u for lighter ions (Ar). The responses to dsb induction for charged particles show direct relationship between increasing radiation dose and residual intact DNA.

Energy gain calculations in spherical IEC fusion systems using the BAFP code

NASA Astrophysics Data System (ADS)

Chacón, L.; Miley, G. H.; Barnes, D. C.; Knoll, D. A.

1999-11-01

The spherical IEC fusion concept takes advantage of the potential well generated by an inner spherical cathode (physical or virtual), biased negatively to several kV with respect to a concentric outer grounded boundary, to focus ions inwards and form a dense central core where fusion may occur. However, defocusing of the ion beams due to ion-ion collisions may prevent a satisfactory energy balance in the system. This research concentrates of spherically symmetric virtual cathode IEC devices, in which a spherical cloud of electrons, confined á la Penning trap, creates the ion-confining electrostatic well. A bounce-averaged Fokker-Planck model has been constructed to analyze the ion physics in ideal conditions (i.e., spherically uniform electrostatic well, no collisional interaction between ions and electrons, single ion species).(L. Chacon, D. C. Barnes, D. A. Knoll, 40^th) Annual Meeting of the APS Division of Plasma Physics, New Orleans, LA, Nov. 1998 Results will reproduce the phenomenology of previously published( W. Nevins, Phys. Plasmas), 2(10), 3804-3819 (1995) theoretical limits, and will show that, under some conditions, steady-state solutions with relatively high gains and small ion recirculation powers exist for the bounce-averaged Fokker-Planck transport equation. Variations in gain with parameter space will be presented.

Improvement of efficiency and temperature control of induction heating vapor source on electron cyclotron resonance ion source.

PubMed

Takenaka, T; Kiriyama, R; Muramatsu, M; Kitagawa, A; Uchida, T; Kurisu, Y; Nozaki, D; Yano, K; Yoshida, Y; Sato, F; Kato, Y; Iida, T

2012-02-01

An electron cyclotron resonance ion source (ECRIS) is used to generate multicharged ions for many kinds of the fields. We have developed an evaporator by using induction heating method that can generate pure vapor from solid state materials in ECRIS. We develop the new matching and protecting circuit by which we can precisely control the temperature of the induction heating evaporator. We can control the temperature within ±15 °C around 1400 °C under the operation pressure about 10(-4) Pa. We are able to use this evaporator for experiment of synthesizing process to need pure vapor under enough low pressure, e.g., experiment of generation of endohedral Fe-fullerene at the ECRIS.

Dynamic effect of leachate recirculation on batch mode solid state anaerobic digestion: Influence of recirculated volume, leachate to substrate ratio and recirculation periodicity.

PubMed

Degueurce, Axelle; Trémier, Anne; Peu, Pascal

2016-09-01

Performances of batch mode solid state anaerobic digestion (SSAD) were investigated through several leachate recirculation strategies. Three parameters were shown to particularly influence methane production rates (MPR) and methane yields: the length of the interval between two recirculation events, the leachate to substrate (L:S) ratio and the volume of leachate recirculated. A central composite factor design was used to determine the influence of each parameter on methane production. Results showed that lengthening the interval between two recirculation events reduced methane yield. This effect can be counteracted by recirculating a large volume of leachate at a low L:S ratio. Steady methane production can be obtained by recirculating small amounts of leachate, and by lengthening the interval between two recirculations, regardless of the L:S ratio. However, several combinations of these parameters led to similar performances meaning that leachate recirculation practices can be modified as required by the specific constraints SSAD plants configurations. Copyright © 2016 Elsevier Ltd. All rights reserved.

Injector for the University of Maryland Electron Ring (UMER)

NASA Astrophysics Data System (ADS)

Kehne, D.; Godlove, T.; Haldemann, P.; Bernal, S.; Guharay, S.; Kishek, R.; Li, Y.; O'Shea, P.; Reiser, M.; Yun, V.; Zou, Y.; Haber, I.

2001-05-01

The electron beam injector constructed by FM technologies for the University of Maryland Electron Ring (UMER) program is described. The program will use an electron beam to model space-charge-dominated ion beams in a recirculating linac for heavy ion inertial fusion, as well as for high-current muon colliders. The injector consists of a 10 keV, 100 mA electron gun with 50-100 nsec pulse width and a repetition rate of 120 Hz. The e-gun system includes a 6-mask, rotatable aperture plate, a Rogowski current monitor, an ion pump, and a gate valve. The injector beamline consists of a solenoid, a five-quadrupole matching section, two diagnostic chambers, and a fast current monitor. An independent diagnostic chamber also built for UMER will be used to measure horizontal and vertical emittance, current, energy, energy spread, and the evolution of the beam envelope and profile along the injector beamline.

Simultaneously reducing CO2 and particulate exposures via fractional recirculation of vehicle cabin air.

PubMed

Jung, Heejung S; Grady, Michael L; Victoroff, Tristan; Miller, Arthur L

2017-07-01

Prior studies demonstrate that air recirculation can reduce exposure to nanoparticles in vehicle cabins. However when people occupy confined spaces, air recirculation can lead to carbon dioxide (CO 2 ) accumulation which can potentially lead to deleterious effects on cognitive function. This study proposes a fractional air recirculation system for reducing nanoparticle concentration while simultaneously suppressing CO 2 levels in the cabin. Several recirculation scenarios were tested using a custom-programmed HVAC (heat, ventilation, air conditioning) unit that varied the recirculation door angle in the test vehicle. Operating the recirculation system with a standard cabin filter reduced particle concentrations to 1000 particles/cm 3 , although CO 2 levels rose to 3000 ppm. When as little as 25% fresh air was introduced (75% recirculation), CO 2 levels dropped to 1000 ppm, while particle concentrations remained below 5000 particles/cm 3 . We found that nanoparticles were removed selectively during recirculation and demonstrated the trade-off between cabin CO 2 concentration and cabin particle concentration using fractional air recirculation. Data showed significant increases in CO 2 levels during 100% recirculation. For various fan speeds, recirculation fractions of 50-75% maintained lower CO 2 levels in the cabin, while still reducing particulate levels. We recommend fractional recirculation as a simple method to reduce occupants' exposures to particulate matter and CO 2 in vehicles. A design with several fractional recirculation settings could allow air exchange adequate for reducing both particulate and CO 2 exposures. Developing this technology could lead to reductions in airborne nanoparticle exposure, while also mitigating safety risks from CO 2 accumulation.

Simultaneously reducing CO2 and particulate exposures via fractional recirculation of vehicle cabin air

PubMed Central

Jung, Heejung S.; Grady, Michael L.; Victoroff, Tristan; Miller, Arthur L.

2017-01-01

Prior studies demonstrate that air recirculation can reduce exposure to nanoparticles in vehicle cabins. However when people occupy confined spaces, air recirculation can lead to carbon dioxide (CO2) accumulation which can potentially lead to deleterious effects on cognitive function. This study proposes a fractional air recirculation system for reducing nanoparticle concentration while simultaneously suppressing CO2 levels in the cabin. Several recirculation scenarios were tested using a custom-programmed HVAC (heat, ventilation, air conditioning) unit that varied the recirculation door angle in the test vehicle. Operating the recirculation system with a standard cabin filter reduced particle concentrations to 1000 particles/cm3, although CO2 levels rose to 3000 ppm. When as little as 25% fresh air was introduced (75% recirculation), CO2 levels dropped to 1000 ppm, while particle concentrations remained below 5000 particles/cm3. We found that nanoparticles were removed selectively during recirculation and demonstrated the trade-off between cabin CO2 concentration and cabin particle concentration using fractional air recirculation. Data showed significant increases in CO2 levels during 100% recirculation. For various fan speeds, recirculation fractions of 50–75% maintained lower CO2 levels in the cabin, while still reducing particulate levels. We recommend fractional recirculation as a simple method to reduce occupants’ exposures to particulate matter and CO2 in vehicles. A design with several fractional recirculation settings could allow air exchange adequate for reducing both particulate and CO2 exposures. Developing this technology could lead to reductions in airborne nanoparticle exposure, while also mitigating safety risks from CO2 accumulation. PMID:28781568

Simultaneously reducing CO2 and particulate exposures via fractional recirculation of vehicle cabin air

NASA Astrophysics Data System (ADS)

Jung, Heejung S.; Grady, Michael L.; Victoroff, Tristan; Miller, Arthur L.

2017-07-01

Prior studies demonstrate that air recirculation can reduce exposure to nanoparticles in vehicle cabins. However when people occupy confined spaces, air recirculation can lead to carbon dioxide (CO2) accumulation which can potentially lead to deleterious effects on cognitive function. This study proposes a fractional air recirculation system for reducing nanoparticle concentration while simultaneously suppressing CO2 levels in the cabin. Several recirculation scenarios were tested using a custom-programmed HVAC (heat, ventilation, air conditioning) unit that varied the recirculation door angle in the test vehicle. Operating the recirculation system with a standard cabin filter reduced particle concentrations to 1000 particles/cm3, although CO2 levels rose to 3000 ppm. When as little as 25% fresh air was introduced (75% recirculation), CO2 levels dropped to 1000 ppm, while particle concentrations remained below 5000 particles/cm3. We found that nanoparticles were removed selectively during recirculation and demonstrated the trade-off between cabin CO2 concentration and cabin particle concentration using fractional air recirculation. Data showed significant increases in CO2 levels during 100% recirculation. For various fan speeds, recirculation fractions of 50-75% maintained lower CO2 levels in the cabin, while still reducing particulate levels. We recommend fractional recirculation as a simple method to reduce occupants' exposures to particulate matter and CO2 in vehicles. A design with several fractional recirculation settings could allow air exchange adequate for reducing both particulate and CO2 exposures. Developing this technology could lead to reductions in airborne nanoparticle exposure, while also mitigating safety risks from CO2 accumulation.

TSR: A storage and cooling ring for HIE-ISOLDE

NASA Astrophysics Data System (ADS)

Butler, P. A.; Blaum, K.; Davinson, T.; Flanagan, K.; Freeman, S. J.; Grieser, M.; Lazarus, I. H.; Litvinov, Yu. A.; Lotay, G.; Page, R. D.; Raabe, R.; Siesling, E.; Wenander, F.; Woods, P. J.

2016-06-01

It is planned to install the heavy-ion, low-energy ring TSR, currently at the Max-Planck-Institute for Nuclear Physics in Heidelberg, at the HIE-ISOLDE facility in CERN, Geneva. Such a facility will provide a capability for experiments with stored, cooled secondary beams that is rich and varied, spanning from studies of nuclear ground-state properties and reaction studies of astrophysical relevance, to investigations with highly-charged ions and pure isomeric beams. In addition to experiments performed using beams recirculating within the ring, the cooled beams can be extracted and exploited by external spectrometers for high-precision measurements. The capabilities of the ring facility as well as some physics cases will be presented, together with a brief report on the status of the project.

Measurements and effects of backstreaming ions produced at bremsstrahlung converter target in Dragon-I linear induction accelerator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yu Haijun; Zhu Jun; Chen Nan

2010-04-15

Positive ions released from x-ray converter target impacted by electron beam of millimeter spot size can be trapped and accelerated in the incident beam's potential well. As the ions move upstream, the beam will be pinched first and then defocused at the target. Four Faraday cups are used to collect backstreaming ions produced at the bremsstrahlung converter target in Dragon-I linear induction accelerator (LIA). Experimental and theoretical results show that the backstreaming positive ions density and velocity are about 10{sup 21}/m{sup 3} and 2-3 mm/{mu}s, respectively. The theoretical and experimental results of electron beam envelope with ions and without ionsmore » are also presented. The discussions show that the backstreaming positive ions will not affect the electron beam focusing and envelope radius in Dragon-I LIA.« less

Induction heating pure vapor source of high temperature melting point materials on electron cyclotron resonance ion source.

PubMed

Kutsumi, Osamu; Kato, Yushi; Matsui, Yuuki; Kitagawa, Atsushi; Muramatsu, Masayuki; Uchida, Takashi; Yoshida, Yoshikazu; Sato, Fuminobu; Iida, Toshiyuki

2010-02-01

Multicharged ions that are needed are produced from solid pure material with high melting point in an electron cyclotron resonance ion source. We develop an evaporator by using induction heating (IH) with multilayer induction coil, which is made from bare molybdenum or tungsten wire without water cooling and surrounding the pure vaporized material. We optimize the shapes of induction coil and vaporized materials and operation of rf power supply. We conduct experiment to investigate the reproducibility and stability in the operation and heating efficiency. IH evaporator produces pure material vapor because materials directly heated by eddy currents have no contact with insulated materials, which are usually impurity gas sources. The power and the frequency of the induction currents range from 100 to 900 W and from 48 to 23 kHz, respectively. The working pressure is about 10(-4)-10(-3) Pa. We measure the temperature of the vaporized materials with different shapes, and compare them with the result of modeling. We estimate the efficiency of the IH vapor source. We are aiming at the evaporator's higher melting point material than that of iron.

Induction heating pure vapor source of high temperature melting point materials on electron cyclotron resonance ion sourcea)

NASA Astrophysics Data System (ADS)

Kutsumi, Osamu; Kato, Yushi; Matsui, Yuuki; Kitagawa, Atsushi; Muramatsu, Masayuki; Uchida, Takashi; Yoshida, Yoshikazu; Sato, Fuminobu; Iida, Toshiyuki

2010-02-01

Multicharged ions that are needed are produced from solid pure material with high melting point in an electron cyclotron resonance ion source. We develop an evaporator by using induction heating (IH) with multilayer induction coil, which is made from bare molybdenum or tungsten wire without water cooling and surrounding the pure vaporized material. We optimize the shapes of induction coil and vaporized materials and operation of rf power supply. We conduct experiment to investigate the reproducibility and stability in the operation and heating efficiency. IH evaporator produces pure material vapor because materials directly heated by eddy currents have no contact with insulated materials, which are usually impurity gas sources. The power and the frequency of the induction currents range from 100to900W and from 48to23kHz, respectively. The working pressure is about 10-4-10-3Pa. We measure the temperature of the vaporized materials with different shapes, and compare them with the result of modeling. We estimate the efficiency of the IH vapor source. We are aiming at the evaporator's higher melting point material than that of iron.

ION-STABILIZED ELECTRON INDUCTION ACCELERATOR

DOEpatents

Finkelstein, D.

1960-03-22

A method and apparatus for establishing an ion-stabilized self-focusing relativistic electron beam from a plasma are reported. A plasma is introduced into a specially designed cavity by plasma guns, and a magnetic field satisfying betatron conditions is produced in the cavity by currents flowing in the highly conductive, non-magnetic surface of the cavity. This field forms the electron beam by induction from the plasma.

Recent thymic emigrants are tolerized in the absence of inflammation

PubMed Central

Friesen, Travis J.; Ji, Qingyong

2016-01-01

T cell development requires a period of postthymic maturation. Why this is the case has remained a mystery, particularly given the rigors of intrathymic developmental checkpoints, successfully traversed by only ∼5% of thymocytes. We now show that the first few weeks of T cell residence in the lymphoid periphery define a period of heightened susceptibility to tolerance induction to tissue-restricted antigens (TRAs), the outcome of which depends on the context in which recent thymic emigrants (RTEs) encounter antigen. After encounter with TRAs in the absence of inflammation, RTEs exhibited defects in proliferation, diminished cytokine production, elevated expression of anergy-associated genes, and diminished diabetogenicity. These properties were mirrored in vitro by enhanced RTE susceptibility to regulatory T cell–mediated suppression. In the presence of inflammation, RTEs and mature T cells were, in contrast, equally capable of inducing diabetes, proliferating, and producing cytokines. Thus, recirculating RTEs encounter TRAs during a transitional developmental stage that facilitates tolerance induction, but inflammation converts antigen-exposed, tolerance-prone RTEs into competent effector cells. PMID:27139493

Mutation induction by heavy ions

NASA Astrophysics Data System (ADS)

Kiefer, J.; Stoll, U.; Schneider, E.

1994-10-01

Mutation induction by heavy ions is compared in yeast and mammalian cells. Since mutants can only be recovered in survivors the influence of inactivation cross sections has to be taken into account. It is shown that both the size of the sensitive cellular site as well as track structure play an important role. Another parameter which influences the probability of mutation induction is repair: Contrary to naive assumptions primary radiation damage does not directly lead to mutations but requires modification to reconstitute the genetic machinery so that mutants can survive. The molecular structure of mutations was analyzed after exposure to deuterons by amplification with the aid of polymerase chain reaction. The results-although preliminary-demonstrate that even with densely ionizing particles a large fraction does not carry big deletions which suggests that point mutations may also be induced by heavy ions.

Investigation on inlet recirculation characteristics of double suction centrifugal compressor with unsymmetrical inlet

NASA Astrophysics Data System (ADS)

Yang, Ce; Wang, Yingjun; Lao, Dazhong; Tong, Ding; Wei, Longyu; Liu, Yixiong

2016-08-01

The inlet recirculation characteristics of double suction centrifugal compressor with unsymmetrical inlet structures were studied in numerical method, mainly focused on three issues including the amounts and differences of the inlet recirculation in different working conditions, the circumferential non-uniform distributions of the inlet recirculation, the recirculation velocity distributions of the upstream slot of the rear impeller. The results show that there are some differences between the recirculation of the front impeller and that of the rear impeller in whole working conditions. In design speed, the recirculation flow rate of the rear impeller is larger than that of the front impeller in the large flow range, but in the small flow range, the recirculation flow rate of the rear impeller is smaller than that of the front impeller. In different working conditions, the recirculation velocity distributions of the front and rear impeller are non-uniform along the circumferential direction and their non-uniform extents are quite different. The circumferential non-uniform extent of the recirculation velocity varies with the working conditions change. The circumferential non-uniform extent of the recirculation velocity of front impeller and its distribution are determined by the static pressure distribution of the front impeller, but that of the rear impeller is decided by the coupling effects of the inlet flow distortion of the rear impeller, the circumferential unsymmetrical distribution of the upstream slot and the asymmetric structure of the volute. In the design flow and small flow conditions, the recirculation velocities at different circumferential positions of the mean line of the upstream slot cross-section of the rear impeller are quite different, and the recirculation velocities distribution forms at both sides of the mean line are different. The recirculation velocity distributions in the cross-section of the upstream slot depend on the static pressure distributions in the intake duct.

Operation of a high impedance applied-B extraction ion diode on the SABRE positive polarity linear induction accelerator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hanson, D.L.; Cuneo, M.E.; McKay, P.F.

We present results from initial experiments with a high impedance applied-B extraction diode on the SABRE ten stage linear induction accelerator (6.7 MV, 300 kA). We have demonstrated efficient coupling of power from the accelerator through an extended MITL (Magnetically Insulated Transmission Line) into a high intensity ion beam. Both MITL electron flow in the diode region and ion diode behavior, including ion source turn-on, virtual cathode formation and evolution, enhancement delay, and ion coupling efficiency, are strongly influenced by the geometry of the diode insulating magnetic field. For our present diode electrode geometry, electrons from the diode feed stronglymore » influence the evolution of the virtual cathode. Both experimental data and particle-in-cell numerical simulations show that uniform insulation of these feed electrons is required for uniform ion emission and efficient diode operation.« less

High intensity ion beams from an atmospheric pressure inductively coupled plasma

NASA Astrophysics Data System (ADS)

Al Moussalami, S.; Chen, W.; Collings, B. A.; Douglas, D. J.

2002-02-01

This work is directed towards substantially improving the sensitivity of an inductively coupled plasma mass spectrometer (ICP-MS). Ions produced in the ICP at atmospheric pressure have been extracted with comparatively high current densities. The conventional approach to ion extraction, based on a skimmed molecular beam, has been abandoned, and a high extraction field arrangement has been adopted. Although the new approach is not optimized, current densities more than 180 times greater than that of a conventional interface have been extracted and analyte sensitivities ˜10-100× greater than those reported previously for quadrupole ICP-MS have been measured.

Environmental impact assessment of leachate recirculation in landfill of municipal solid waste by comparing with evaporation and discharge (EASEWASTE).

PubMed

Xing, Wei; Lu, Wenjing; Zhao, Yan; Zhang, Xu; Deng, Wenjing; Christensen, Thomas H

2013-02-01

In some arid regions where landfill produces minimal amount of leachate, leachate recirculation is suggested as a cost-effective option. However, its long-term impacts to environment remain disputed. For the purpose of revealing the environmental impacts of leachate recirculation in landfill, four scenarios were modeled using EASEWASTE, comparing the strategies of leachate recirculation (with or without gas management), evaporation and discharge. In the current situation (Scenario A), a total of 280 t of waste was generated and then transported to a conventional landfill for disposal. A number of contaminants derived from waste can be stored in the landfill for long periods, with 11.69 person equivalent (PE) for stored ecotoxicity in water and 29.62 PE for stored ecotoxicity in soil, considered as potential risks of releasing to the environment someday. Meanwhile, impacts to ecotoxicity and human toxicity in surface water, and those to groundwater, present relatively low levels. In Scenario B, leachate evaporation in a collecting pool has minimal impacts on surface water. However, this strategy significantly impacts groundwater (1055.16 PE) because of the potential infiltration of leachate, with major contaminants of As, ammonia, and Cd. A number of ions, such as Cl(-), Mg(2+), and Ca(2+), may also contaminate groundwater. In Scenario C, the direct discharge of leachate to surface water may result in acidification (2.71 PE) and nutrient enrichment (2.88 PE), primarily attributed to soluble ammonia in leachate and the depositional ammonia from biogas. Moreover, the direct discharge of leachate may also result in ecotoxicity and human toxicity via water contaminated by heavy metals in leachate, with 3.96 PE and 11.64 PE respectively. The results also show that landfill gas is the main contributor to global warming and photochemical ozone formation due to methane emission. In Scenario D, landfill gas flaring was thus be modeled and proven to be efficient for reducing impacts by approximately 90% in most categories, like global warming, photochemical ozone formation, acidification, nutrient enrichment, ecotoxicity, and human toxicity. Therefore, leachate recirculation is considered a cost-effective and environmentally viable solution for the current situation, and landfill gas treatment is urgently required. These results can provide important evidence for leachate and gas management of landfill in arid regions. Copyright © 2012 Elsevier Ltd. All rights reserved.

Construction and commissioning of the compact energy-recovery linac at KEK

NASA Astrophysics Data System (ADS)

Akemoto, Mitsuo; Arakawa, Dai; Asaoka, Seiji; Cenni, Enrico; Egi, Masato; Enami, Kazuhiro; Endo, Kuninori; Fukuda, Shigeki; Furuya, Takaaki; Haga, Kaiichi; Hajima, Ryoichi; Hara, Kazufumi; Harada, Kentaro; Honda, Tohru; Honda, Yosuke; Honma, Teruya; Hosoyama, Kenji; Kako, Eiji; Katagiri, Hiroaki; Kawata, Hiroshi; Kobayashi, Yukinori; Kojima, Yuuji; Kondou, Yoshinari; Tanaka, Olga; Kume, Tatsuya; Kuriki, Masao; Matsumura, Hiroshi; Matsushita, Hideki; Michizono, Shinichiro; Miura, Takako; Miyajima, Tsukasa; Nagahashi, Shinya; Nagai, Ryoji; Nakai, Hirotaka; Nakajima, Hiromitsu; Nakamura, Norio; Nakanishi, Kota; Nigorikawa, Kazuyuki; Nishimori, Nobuyuki; Nogami, Takashi; Noguchi, Shuichi; Obina, Takashi; Qiu, Feng; Sagehashi, Hidenori; Sakai, Hiroshi; Sakanaka, Shogo; Sasaki, Shinichi; Satoh, Kotaro; Sawamura, Masaru; Shimada, Miho; Shinoe, Kenji; Shishido, Toshio; Tadano, Mikito; Takahashi, Takeshi; Takai, Ryota; Takenaka, Tateru; Tanimoto, Yasunori; Uchiyama, Takashi; Ueda, Akira; Umemori, Kensei; Watanabe, Ken; Yamamoto, Masahiro

2018-01-01

Energy-recovery linacs (ERLs) are promising for advanced synchrotron light sources, high-power free electron lasers (FELs), high-brightness gamma-ray sources, and electron-ion colliders. To demonstrate the critical technology of ERL-based light sources, we have designed and constructed a test accelerator, the compact ERL (cERL). Using advanced technology that includes a photocathode direct current (DC) electron gun and two types of 1.3-GHz-frequency superconducting cavities, the cERL was designed to be capable of recirculating low emittance (≤1 mm ṡ mrad) and high average-current (≥10 mA) electron beams while recovering the beam energy. During initial commissioning, the cERL demonstrated successful recirculation of high-quality beams with normalized transverse emittance of ∼0.14 mm ṡ mrad and momentum spread of ∼1.2 × 10-4 (rms) at a beam energy of 20 MeV and bunch charge below 100 fC. Energy recovery in the superconducting main linac was also demonstrated for high-average-current continuous-wave beams. These results constitute an important milestone toward realizing ERL-based light sources.

Nitrogen oxides emissions from the MILD combustion with the conditions of recirculation gas.

PubMed

Park, Min; Shim, Sung Hoon; Jeong, Sang Hyun; Oh, Kwang-Joong; Lee, Sang-Sup

2017-04-01

The nitrogen oxides (NO x ) reduction technology by combustion modification which has economic benefits as a method of controlling NO x emitted in the combustion process, has recently been receiving a lot of attention. Especially, the moderate or intense low oxygen dilution (MILD) combustion which applied high temperature flue gas recirculation has been confirmed for its effectiveness with regard to solid fuel as well. MILD combustion is affected by the flue gas recirculation ratio and the composition of recirculation gas, so its NO x reduction efficiency is determined by them. In order to investigate the influence of factors which determine the reduction efficiency of NO x in MILD coal combustion, this study changed the flow rate and concentration of nitrogen (N 2 ), carbon dioxide (CO 2 ) and steam (H 2 O) which simulate the recirculation gas during the MILD coal combustion using our lab-scale drop tube furnace and performed the combustion experiment. As a result, its influence by the composition of recirculation gas was insignificant and it was shown that flue gas recirculation ratio influences the change of NO x concentration greatly. We investigated the influence of factors determining the nitrogen oxides (NO x ) reduction efficiency in MILD coal combustion, which applied high-temperature flue gas recirculation. Using a lab-scale drop tube furnace and simulated recirculation gas, we conducted combustion testing changing the recirculation gas conditions. We found that the flue gas recirculation ratio influences the reduction of NO x emissions the most.

Exhaust gas recirculation system for an internal combustion engine

DOEpatents

Wu, Ko-Jen

2013-05-21

An exhaust gas recirculation system for an internal combustion engine comprises an exhaust driven turbocharger having a low pressure turbine outlet in fluid communication with an exhaust gas conduit. The turbocharger also includes a low pressure compressor intake and a high pressure compressor outlet in communication with an intake air conduit. An exhaust gas recirculation conduit fluidly communicates with the exhaust gas conduit to divert a portion of exhaust gas to a low pressure exhaust gas recirculation branch extending between the exhaust gas recirculation conduit and an engine intake system for delivery of exhaust gas thereto. A high pressure exhaust gas recirculation branch extends between the exhaust gas recirculation conduit and the compressor intake and delivers exhaust gas to the compressor for mixing with a compressed intake charge for delivery to the intake system.

DNA fragmentation induced by Fe ions in human cells: shielding influence on spatially correlated damage

NASA Technical Reports Server (NTRS)

Antonelli, F.; Belli, M.; Campa, A.; Chatterjee, A.; Dini, V.; Esposito, G.; Rydberg, B.; Simone, G.; Tabocchini, M. A.

2004-01-01

Outside the magnetic field of the Earth, high energy heavy ions constitute a relevant part of the biologically significant dose to astronauts during the very long travels through space. The typical pattern of energy deposition in the matter by heavy ions on the microscopic scale is believed to produce spatially correlated damage in the DNA which is critical for radiobiological effects. We have investigated the influence of a lucite shielding on the initial production of very small DNA fragments in human fibroblasts irradiated with 1 GeV/u iron (Fe) ions. We also used gamma rays as reference radiation. Our results show: (1) a lower effect per incident ion when the shielding is used; (2) an higher DNA Double Strand Breaks (DSB) induction by Fe ions than by gamma rays in the size range 1-23 kbp; (3) a non-random DNA DSB induction by Fe ions. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Neoplastic transformation of hamster embryo cells by heavy ions

NASA Astrophysics Data System (ADS)

Han, Z.; Suzuki, H.; Suzuki, F.; Suzuki, M.; Furusawa, Y.; Kato, T.; Ikenaga, M.

1998-11-01

We have studied the induction of morphological transformation of Syrian hamster embryo cells by low doses of heavy ions with different linear energy transfer (LET), ranging from 13 to 400 keV/μm. Exponentially growing cells were irradiated with 12C or 28Si ion beams generated by the Heavy Ion Medical Accelerator in Chiba (HIMAC), inoculated to culture dishes, and transformed colonies were identified when the cells were densely stacked and showed a crisscross pattern. Over the LET range examined, the frequency of transformation induced by the heavy ions increased sharply at very low doses no greater than 5 cGy. The relative biological effectiveness (RBE) of the heavy ions relative to 250 kVp X-rays showed an initial increase with LET, reaching a maximum value of about 7 at 100 keV/μm, and then decreased with the further increase in LET. Thus, we confirmed that high LET heavy ions are significantly more effective than X-rays for the induction of in vitro cell transformation.

Relative biological effectiveness of accelerated heavy ions for induction of morphological transformation in Syrian hamster embryo cells.

PubMed

Han, Z B; Suzuki, H; Suzuki, F; Suzuki, M; Furusawa, Y; Kato, T; Ikenaga, M

1998-09-01

Syrian hamster embryo cells were used to study the morphological transformation induced by accelerated heavy ions with different linear energy transfer (LET) ranging from 13 to 400 keV/micron. Exponentially growing cells were irradiated with 12C or 28Si ion beams generated by the Heavy Ion Medical Accelerator in Chiba (HIMAC), then inoculated to culture dishes. Morphologically altered colonies were scored as transformants. Over the LET range examined, the frequency of transformation induced by the heavy ions increased sharply at very low doses no greater than 5 cGy. The relative biological effectiveness (RBE) of the heavy ions relative to X-rays first increased with LET, reached a maximum value of about 7 at 100 keV/micron, then decreased with the further increase of LET. Our findings confirmed that high LET heavy ions are much more effective than X-rays for the induction of in vitro cell transformation.

Neoplastic transformation of hamster embyro cells by heavy ions.

PubMed

Han, Z; Suzuki, H; Suzuki, F; Suzuki, M; Furusawa, Y; Kato, T; Ikenaga, M

1998-01-01

We have studied the induction of morphological transformation of Syrian hamster embryo cells by low doses of heavy ions with different linear energy transfer (LET), ranging from 13 to 400 keV/micrometer. Exponentially growing cells were irradiated with 12C or 28Si ion beams generated by the Heavy Ion Medical Accelerator in Chiba (HIMAC), inoculated to culture dishes, and transformed colonies were identified when the cells were densely stacked and showed a crisscross pattern. Over the LET range examined, the frequency of transformation induced by the heavy ions increased sharply at very low doses no greater than 5 cGy. The relative biological effectiveness (RBE) of the heavy ions relative to 250 kVp X-rays showed an initial increase with LET, reaching a maximum value of about 7 at 100 keV/micrometer, and then decreased with the further increase in LET. Thus, we confirmed that high LET heavy ions are significantly more effective than X-rays for the induction of in vitro cell transformation.

Computational Assessment of a 3-Stage Axial Compressor Which Provides Airflow to the NASA 11- by 11-Foot Transonic Wind Tunnel, Including Design Changes for Increased Performance

NASA Technical Reports Server (NTRS)

Kulkarni, Sameer; Beach, Timothy A.; Jorgenson, Philip C.; Veres, Joseph P.

2017-01-01

A 24 foot diameter 3-stage axial compressor powered by variable-speed induction motors provides the airflow in the closed-return 11- by 11-Foot Transonic Wind Tunnel (11-Foot TWT) Facility at NASA Ames Research Center at Moffett Field, California. The facility is part of the Unitary Plan Wind Tunnel, which was completed in 1955. Since then, upgrades made to the 11-Foot TWT such as flow conditioning devices and instrumentation have increased blockage and pressure loss in the tunnel, somewhat reducing the peak Mach number capability of the test section. Due to erosion effects on the existing aluminum alloy rotor blades, fabrication of new steel rotor blades is planned. This presents an opportunity to increase the Mach number capability of the tunnel by redesigning the compressor for increased pressure ratio. Challenging design constraints exist for any proposed design, demanding the use of the existing driveline, rotor disks, stator vanes, and hub and casing flow paths, so as to minimize cost and installation time. The current effort was undertaken to characterize the performance of the existing compressor design using available design tools and computational fluid dynamics (CFD) codes and subsequently recommend a new compressor design to achieve higher pressure ratio, which directly correlates with increased test section Mach number. The constant cross-sectional area of the compressor leads to highly diffusion factors, which presents a challenge in simulating the existing design. The CFD code APNASA was used to simulate the aerodynamic performance of the existing compressor. The simulations were compared to performance predictions from the HT0300 turbomachinery design and analysis code, and to compressor performance data taken during a 1997 facility test. It was found that the CFD simulations were sensitive to endwall leakages associated with stator buttons, and to a lesser degree, under-stator-platform flow recirculation at the hub. When stator button leakages were modeled, pumping capability increased by over 20 of pressure rise at design point due to a large reduction in aerodynamic blockage at the hub. Incorporating the stator button leakages was crucial to matching test data. Under-stator-platform flow recirculation was thought to be large due to a lack of seals. The effect of this recirculation was assessed with APNASA simulations recirculating 0.5, 1, and 2 of inlet flow about stators 1 and 2, modeled as axisymmetric mass flux boundary conditions on the hub before and after the vanes. The injection of flow ahead of the stators tended to re-energize the boundary layer and reduce hub separations, resulting in about 3 increased stall margin per 1 of inlet flow recirculated. In order to assess the value of the flow recirculation, a mixing plane simulation of the compressor which gridded the under-stator cavities was generated using the ADPAC CFD code. This simulation indicated that about 0.65 of the inlet flow is recirculated around each shrouded stator. This collective information was applied during the redesign of the compressor. A potential design was identified using HT0300 which improved overall pressure ratio by removing pre-swirl into rotor 1, replacing existing NASA 65 series rotors with double circular arc sections, and re-staggering rotors and the existing stators. The performance of the new design predicted by APNASA and HT0300 is compared to the existing design.

Development of a high current 60 keV neutral lithium beam injector for beam emission spectroscopy measurements on fusion experiments.

PubMed

Anda, G; Dunai, D; Lampert, M; Krizsanóczi, T; Németh, J; Bató, S; Nam, Y U; Hu, G H; Zoletnik, S

2018-01-01

A 60 keV neutral lithium beam system was designed and built up for beam emission spectroscopy measurement of edge plasma on the KSTAR and EAST tokamaks. The electron density profile and its fluctuation can be measured using the accelerated lithium beam-based emission spectroscopy system. A thermionic ion source was developed with a SiC heater to emit around 4-5 mA ion current from a 14 mm diameter surface. The ion optic is following the 2 step design used on other devices with small modifications to reach about 2-3 cm beam diameter in the plasma at about 4 m from the ion source. A newly developed recirculating sodium vapour neutralizer neutralizes the accelerated ion beam at around 260-280 °C even during long (<20 s) discharges. A set of new beam diagnostic and manipulation techniques are applied to allow optimization, aiming, cleaning, and beam modulation. The maximum 60 keV beam energy with 4 mA ion current was successfully reached at KSTAR and at EAST. Combined with an efficient observation system, the Li-beam diagnostic enables the measurement of the density profile and fluctuations on the plasma turbulence time scale.

Development of a high current 60 keV neutral lithium beam injector for beam emission spectroscopy measurements on fusion experiments

NASA Astrophysics Data System (ADS)

Anda, G.; Dunai, D.; Lampert, M.; Krizsanóczi, T.; Németh, J.; Bató, S.; Nam, Y. U.; Hu, G. H.; Zoletnik, S.

2018-01-01

A 60 keV neutral lithium beam system was designed and built up for beam emission spectroscopy measurement of edge plasma on the KSTAR and EAST tokamaks. The electron density profile and its fluctuation can be measured using the accelerated lithium beam-based emission spectroscopy system. A thermionic ion source was developed with a SiC heater to emit around 4-5 mA ion current from a 14 mm diameter surface. The ion optic is following the 2 step design used on other devices with small modifications to reach about 2-3 cm beam diameter in the plasma at about 4 m from the ion source. A newly developed recirculating sodium vapour neutralizer neutralizes the accelerated ion beam at around 260-280 °C even during long (<20 s) discharges. A set of new beam diagnostic and manipulation techniques are applied to allow optimization, aiming, cleaning, and beam modulation. The maximum 60 keV beam energy with 4 mA ion current was successfully reached at KSTAR and at EAST. Combined with an efficient observation system, the Li-beam diagnostic enables the measurement of the density profile and fluctuations on the plasma turbulence time scale.

21 CFR 880.5045 - Medical recirculating air cleaner.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Medical recirculating air cleaner. 880.5045... Therapeutic Devices § 880.5045 Medical recirculating air cleaner. (a) Identification. A medical recirculating air cleaner is a device used to remove particles from the air for medical purposes. The device may...

21 CFR 880.5045 - Medical recirculating air cleaner.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Medical recirculating air cleaner. 880.5045... Therapeutic Devices § 880.5045 Medical recirculating air cleaner. (a) Identification. A medical recirculating air cleaner is a device used to remove particles from the air for medical purposes. The device may...

21 CFR 880.5045 - Medical recirculating air cleaner.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Medical recirculating air cleaner. 880.5045... Therapeutic Devices § 880.5045 Medical recirculating air cleaner. (a) Identification. A medical recirculating air cleaner is a device used to remove particles from the air for medical purposes. The device may...

21 CFR 880.5045 - Medical recirculating air cleaner.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Medical recirculating air cleaner. 880.5045 Section 880.5045 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Therapeutic Devices § 880.5045 Medical recirculating air cleaner. (a) Identification. A medical recirculating...

21 CFR 880.5045 - Medical recirculating air cleaner.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Medical recirculating air cleaner. 880.5045 Section 880.5045 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Therapeutic Devices § 880.5045 Medical recirculating air cleaner. (a) Identification. A medical recirculating...

The NDCX-II engineering design

NASA Astrophysics Data System (ADS)

Waldron, W. L.; Abraham, W. J.; Arbelaez, D.; Friedman, A.; Galvin, J. E.; Gilson, E. P.; Greenway, W. G.; Grote, D. P.; Jung, J.-Y.; Kwan, J. W.; Leitner, M.; Lidia, S. M.; Lipton, T. M.; Reginato, L. L.; Regis, M. J.; Roy, P. K.; Sharp, W. M.; Stettler, M. W.; Takakuwa, J. H.; Volmering, J.; Vytla, V. K.

2014-01-01

The Neutralized Drift Compression Experiment (NDCX-II) is a user facility located at Lawrence Berkeley National Laboratory which is uniquely designed for ion-beam-driven high energy density laboratory physics and heavy ion fusion research. Construction was completed in March 2012 and the facility is now in the commissioning phase. A significant amount of engineering was carried out in order to meet the performance parameters required for a wide range of target heating experiments while making the most cost-effective use of high-value hardware available from a decommissioned high current electron induction accelerator. The technical challenges and design of this new ion induction accelerator facility are described.

Apparatus for reduction of selected ion intensities in confined ion beams

DOEpatents

Eiden, Gregory C.; Barinaga, Charles J.; Koppenaal, David W.

2001-01-01

An apparatus for producing an ion beam having an increased proportion of analyte ions compared to carrier gas ions is disclosed. Specifically, the apparatus has an ion trap or a collision cell containing a reagent gas wherein the reagent gas accepts charge from the analyte ions thereby selectively neutralizing the carrier gas ions. Also disclosed is the collision cell as employed in various locations within analytical instruments including an inductively coupled plasma mass spectrometer.

3D Visualization of Monte-Carlo Simulation's of HZE Track Structure and Initial Chemical Species

NASA Technical Reports Server (NTRS)

Plante, Ianik; Cucinotta, Francis A.

2009-01-01

Heavy ions biophysics is important for space radiation risk assessment [1] and hadron-therapy [2]. The characteristic of heavy ions tracks include a very high energy deposition region close to the track (<20 nm) denoted as the track core, and an outer penumbra region consisting of individual secondary electrons (6-rays). A still open question is the radiobiological effects of 6- rays relative to the track core. Of importance is the induction of double-strand breaks (DSB) [3] and oxidative damage to the biomolecules and the tissue matrix, considered the most important lesions for acute and long term effects of radiation. In this work, we have simulated a 56Fe26+ ion track of 1 GeV/amu with our Monte-Carlo code RITRACKS [4]. The simulation results have been used to calculate the energy depiction and initial chemical species in a "voxelized" space, which is then visualized in 3D. Several voxels with dose >1000 Gy are found in the penumbra, some located 0.1 mm from the track core. In computational models, the DSB induction probability is calculated with radial dose [6], which may not take into account the higher RBE of electron track ends for DSB induction. Therefore, these simulations should help improve models of DSB induction and our understanding of heavy ions biophysics.

Low-Temperature Selective Growth of Tungsten Oxide Nanowires by Controlled Nanoscale Stress Induction

PubMed Central

Na, Hyungjoo; Eun, Youngkee; Kim, Min-Ook; Choi, Jungwook; Kim, Jongbaeg

2015-01-01

We report a unique approach for the patterned growth of single-crystalline tungsten oxide (WOx) nanowires based on localized stress-induction. Ions implanted into the desired growth area of WOx thin films lead to a local increase in the compressive stress, leading to the growth of nanowire at lower temperatures (600 °C vs. 750–900 °C) than for equivalent non-implanted samples. Nanowires were successfully grown on the microscale patterns using wafer-level ion implantation and on the nanometer scale patterns using a focused ion beam (FIB). Experimental results show that nanowire growth is influenced by a number of factors including the dose of the implanted ions and their atomic radius. The implanted-ion-assisted, stress-induced method proposed here for the patterned growth of WOx nanowires is simpler than alternative approaches and enhances the compatibility of the process by reducing the growth temperature. PMID:26666843

Diagnostic studies of ion beam formation in inductively coupled plasma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jacobs, Jenee L.

2015-01-01

This dissertation describes a variety of studies focused on the plasma and the ion beam in inductively coupled plasma mass spectrometry (ICP-MS). The ability to use ICP-MS for measurements of trace elements in samples requires the analytes to be efficiently ionized. Updated ionization efficiency tables are discussed for ionization temperatures of 6500 K and 7000 K with an electron density of 1 x 10 15 cm -3. These values are reflective of the current operating parameters of ICP-MS instruments. Calculations are also discussed for doubly charged (M 2+) ion formation, neutral metal oxide (MO) ionization, and metal oxide (MO +)more » ion dissociation for similar plasma temperature values. Ionization efficiency results for neutral MO molecules in the ICP have not been reported previously.« less

Removal of hexavalent chromium by biosorption process in rotating packed bed.

PubMed

Panda, M; Bhowal, A; Datta, S

2011-10-01

Removal of hexavalent chromium ions from an aqueous solution by crude tamarind (Tamarindus indica) fruit shell was examined in a rotating packed bed contactor by continuously recirculating a given volume of solution through the bed. Reduction of Cr(VI) to Cr(III) within the biosorbent appeared to be the removal mechanism. Depletion rate of Cr(VI) from, and release of reduced Cr(III) ions into the aqueous phase, was influenced by mass transfer resistance besides pH and packing depth. A mathematical model considering the reduction reaction to be irreversible and incorporating intraparticle and external phase mass transfer resistances represented the experimental data adequately. The study indicated that the limitations of fixed bed contactor operating under terrestrial gravity in intensifying mass transfer rates for this system can be overcome with rotating packed bed due to liquid flow under centrifugal acceleration.

High ratio recirculating gas compressor

DOEpatents

Weinbrecht, J.F.

1989-08-22

A high ratio positive displacement recirculating rotary compressor is disclosed. The compressor includes an integral heat exchanger and recirculation conduits for returning cooled, high pressure discharge gas to the compressor housing to reducing heating of the compressor and enable higher pressure ratios to be sustained. The compressor features a recirculation system which results in continuous and uninterrupted flow of recirculation gas to the compressor with no direct leakage to either the discharge port or the intake port of the compressor, resulting in a capability of higher sustained pressure ratios without overheating of the compressor. 10 figs.

Method for reduction of selected ion intensities in confined ion beams

DOEpatents

Eiden, Gregory C.; Barinaga, Charles J.; Koppenaal, David W.

1998-01-01

A method for producing an ion beam having an increased proportion of analyte ions compared to carrier gas ions is disclosed. Specifically, the method has the step of addition of a charge transfer gas to the carrier analyte combination that accepts charge from the carrier gas ions yet minimally accepts charge from the analyte ions thereby selectively neutralizing the carrier gas ions. Also disclosed is the method as employed in various analytical instruments including an inductively coupled plasma mass spectrometer.

Method for reduction of selected ion intensities in confined ion beams

DOEpatents

Eiden, G.C.; Barinaga, C.J.; Koppenaal, D.W.

1998-06-16

A method for producing an ion beam having an increased proportion of analyte ions compared to carrier gas ions is disclosed. Specifically, the method has the step of addition of a charge transfer gas to the carrier analyte combination that accepts charge from the carrier gas ions yet minimally accepts charge from the analyte ions thereby selectively neutralizing the carrier gas ions. Also disclosed is the method as employed in various analytical instruments including an inductively coupled plasma mass spectrometer. 7 figs.

Improved efficiency and precise temperature control of low-frequency induction-heating pure iron vapor source on ECR ion source

NASA Astrophysics Data System (ADS)

Kato, Y.; Takenaka, T.; Yano, K.; Kiriyama, R.; Kurisu, Y.; Nozaki, D.; Muramatsu, M.; Kitagawa, A.; Uchida, T.; Yoshida, Y.; Sato, F.; Iida, T.

2012-11-01

Multiply charged ions to be used prospectively are produced from solid pure material in an electron cyclotron resonance ion source (ECRIS). Recently a pure iron source is also required for the production of caged iron ions in the fullerene in order to control cells in vivo in bio-nano science and technology. We adopt directly heating iron rod by induction heating (IH) because it has non-contact with insulated materials which are impurity gas sources. We choose molybdenum wire for the IH coils because it doesn't need water cooling. To improve power efficiency and temperature control, we propose to the new circuit without previously using the serial and parallel dummy coils (SPD) for matching and safety. We made the circuit consisted of inductively coupled coils which are thin-flat and helix shape, and which insulates the IH power source from the evaporator. This coupling coils circuit, i.e. insulated induction heating coil transformer (IHCT), can be move mechanically. The secondary current can be adjusted precisely and continuously. Heating efficiency by using the IHCT is much higher than those of previous experiments by using the SPD, because leakage flux is decreased and matching is improved simultaneously. We are able to adjust the temperature in heating the vapor source around melting point. And then the vapor pressure can be controlled precisely by using the IHCT. We can control ±10K around 1500°C by this method, and also recognize to controlling iron vapor flux experimentally in the extreme low pressures. Now we come into next stage of developing induction heating vapor source for materials with furthermore high temperature melting points above 2000K with the IHCT, and then apply it in our ECRIS.

Coastal recirculation potential affecting air pollutants in Portugal: The role of circulation weather types

NASA Astrophysics Data System (ADS)

Russo, Ana; Gouveia, Célia; Levy, Ilan; Dayan, Uri; Jerez, Sonia; Mendes, Manuel; Trigo, Ricardo

2016-06-01

Coastal zones are under increasing development and experience air pollution episodes regularly. These episodes are often related to peaks in local emissions from industry or transportation, but can also be associated with regional transport from neighbour urban areas influenced by land-sea breeze recirculation. This study intends to analyze the relation between circulation weather patterns, air mass recirculation and pollution levels in three coastal airsheds of Portugal (Lisbon, Porto and Sines) based on the application of an objective quantitative measure of potential recirculation. Although ventilation events have a dominant presence throughout the studied 9-yrs period on all the three airsheds, recirculation and stagnation conditions occur frequently. The association between NO2, SO2 and O3 levels and recirculation potential is evident during summer months. Under high average recirculation potential and high variability, NO2 and SO2 levels are higher for the three airsheds, whilst for O3 each airshed responds differently. This indicates a high heterogeneity among the three airsheds in (1) the type of emission - traffic or industry - prevailing for each contaminant, and (2) the response to the various circulation weather patterns and recirculation situations. Irrespectively of that, the proposed methodology, based on iterative K-means clustering, allows to identify which prevailing patterns are associated with high recirculation potential, having the advantage of being applicable to any geographical location.

Recirculating Air Filtration Significantly Reduces Exposure to Airborne Nanoparticles

PubMed Central

Pui, David Y.H.; Qi, Chaolong; Stanley, Nick; Oberdörster, Günter; Maynard, Andrew

2008-01-01

Background Airborne nanoparticles from vehicle emissions have been associated with adverse effects in people with pulmonary and cardiovascular disease, and toxicologic studies have shown that nanoparticles can be more hazardous than their larger-scale counterparts. Recirculating air filtration in automobiles and houses may provide a low-cost solution to reducing exposures in many cases, thus reducing possible health risks. Objectives We investigated the effectiveness of recirculating air filtration on reducing exposure to incidental and intentionally produced airborne nanoparticles under two scenarios while driving in traffic, and while generating nanomaterials using gas-phase synthesis. Methods We tested the recirculating air filtration in two commercial vehicles when driving in traffic, as well as in a nonventilation room with a nanoparticle generator, simulating a nanomaterial production facility. We also measured the time-resolved aerosol size distribution during the in-car recirculation to investigate how recirculating air filtration affects particles of different sizes. We developed a recirculation model to describe the aerosol concentration change during recirculation. Results The use of inexpensive, low-efficiency filters in recirculation systems is shown to reduce nanoparticle concentrations to below levels found in a typical office within 3 min while driving through heavy traffic, and within 20 min in a simulated nanomaterial production facility. Conclusions Development and application of this technology could lead to significant reductions in airborne nanoparticle exposure, reducing possible risks to health and providing solutions for generating nanomaterials safely. PMID:18629306

Simplified liquid oxygen propellant conditioning concepts

NASA Technical Reports Server (NTRS)

Cleary, N. L.; Holt, K. A.; Flachbart, R. H.

1995-01-01

Current liquid oxygen feed systems waste propellant and use hardware, unnecessary during flight, to condition the propellant at the engine turbopumps prior to launch. Simplified liquid oxygen propellant conditioning concepts are being sought for future launch vehicles. During a joint program, four alternative propellant conditioning options were studied: (1) passive recirculation; (2) low bleed through the engine; (3) recirculation lines; and (4) helium bubbling. The test configuration for this program was based on a vehicle design which used a main recirculation loop that was insulated on the downcomer and uninsulated on the upcomer. This produces a natural convection recirculation flow. The test article for this program simulated a feedline which ran from the main recirculation loop to the turbopump. The objective was to measure the temperature profile of this test article. Several parameters were varied from the baseline case to determine their effects on the temperature profile. These parameters included: flow configuration, feedline slope, heat flux, main recirculation loop velocity, pressure, bleed rate, helium bubbling, and recirculation lines. The heat flux, bleed rate, and recirculation configurations produced the greatest changes from the baseline temperature profile. However, the temperatures in the feedline remained subcooled. Any of the options studied could be used in future vehicles.

A comparative study on low-energy ion beam and neutralized beam modifications of naked DNA and biological effect on mutation

NASA Astrophysics Data System (ADS)

Sarapirom, S.; Thongkumkoon, P.; Prakrajang, K.; Anuntalabhochai, S.; Yu, L. D.

2012-02-01

DNA conformation change or damage induced by low-energy ion irradiation has been of great interest owing to research developments in ion beam biotechnology and ion beam application in biomedicine. Mechanisms involved in the induction of DNA damage may account for effect from implanting ion charge. In order to check this effect, we used both ion beam and neutralized beam at keV energy to bombard naked DNA. Argon or nitrogen ion beam was generated and extracted from a radiofrequency (RF) ion source and neutralized by microwave-driven plasma in the beam path. Plasmid DNA pGFP samples were irradiated with the ion or neutralized beam in vacuum, followed by gel electrophoresis to observe changes in the DNA conformations. It was revealed that the ion charge played a certain role in inducing DNA conformation change. The subsequent DNA transfer into bacteria Escherichia coli ( E. coli) for mutation analysis indicated that the charged ion beam induced DNA change had high potential in mutation induction while neutralized beam did not. The intrinsic reason was attributed to additional DNA deformation and contortion caused by ion charge exchange effect so that the ion beam induced DNA damage could hardly be completely repaired, whereas the neutralized beam induced DNA change could be more easily recoverable owing to absence of the additional DNA deformation and contortion.

Tumor induction in mice after local irradiation with single doses of either carbon-ion beams or gamma rays.

PubMed

Ando, Koichi; Koike, Sachiko; Ohmachi, Yasushi; Ando, Yutaka; Kobashi, Gen

2014-12-01

To determine the dose-dependent relative biological effectiveness (RBE) for tumor prevalence in mice receiving single localized doses to their right leg of either carbon ions (15, 45 or 75 keV/μm) or 137Cs gamma rays. A total of 1647 female C3H mice were irradiated to their hind legs with a localized dose of either reference gamma rays or 15, 45 or 75 keV/μm carbon-ion beams. Irradiated mice were evaluated for tumors twice a month during their three-year life span, and the dimensions of any tumors found were measured with a caliper. The tumor induction frequency was calculated by Kaplan-Meier analysis. The incidence of tumors from 50 Gy of 45 keV/μm carbon ions was marginally higher than those from 50 Gy of gamma rays. However, 60 Gy of 15 keV/μm carbon ions induced significantly fewer tumors than did gamma rays. RBE values of 0.87 + 0.12, 1.29 + 0.08 or 2.06 + 0.39 for lifetime tumorigenesis were calculated for 15, 45 or 75 keV/μm carbon-ion beams, respectively. Fibrosarcoma predominated, with no Linear Energy Transfer (LET)-dependent differences in the tumor histology. Experiments measuring the late effect of leg skin shrinkage suggested that the carcinogenic damage of 15 keV/μm carbon ions would be less than that of gamma rays. We conclude that patients receiving radiation doses to their normal tissues would face less risk of secondary tumor induction by carbon ions of intermediate LET values compared to equivalent doses of photons.

DNA double strand break induction in yeast.

PubMed

Kiefer, J; Egenolf, R; Ikpeme, S E

2002-01-01

The induction of DNA double strand breaks (DSBs) by accelerated heavy ions was systematically measured in diploid yeast cells. Particles were provided by the accelerators at GSI, Darmstadt, and HMI, Berlin. DNA was separated using pulsed field gel electrophoresis and the intensity of the largest bands used to determine the loss of molecular weight. Since the DNA content of each chromosome is exactly known absolute values for DSB induction can be measured without calibration procedures. Ions used range from protons to uranium with LET values between 2 and about 15,000 keV.micron-1. Induction cross sections increase in the lower LET region approaching a plateau around 200 keV.micron-1. With higher LET values the dependence can no longer be described by a common curve with each ion showing a specific behaviour. With very heavy particles the influence of the penumbra becomes obvious: cross sections decrease with LET because of the reduced penumbra extensions. Classical target theory would predict cross sections to follow a simple saturation function which is not substantiated by the data. Track structure analysis as introduced by Butts and Katz in 1967 is also not able to predict the experimental results. A semi-empirical fit indicates a linear-quadratic dependence of induction cross sections on LET up to about 1000 keV.micron-1. RBE for DSB induction rises above unity reaching a maximum of about 2.5 around 200 keV.micron-1. This is different from many experiments in mammalian cells and is presumably due to differences in chromatin structure since yeast cells seem to lack a functional III histone.

Cell inactivation, repair and mutation induction in bacteria after heavy ion exposure: results from experiments at accelerators and in space.

PubMed

Horneck, G; Schafer, M; Baltschukat, K; Weisbrod, U; Micke, U; Facius, R; Bucker, H

1989-01-01

To understand the mechanisms of accelerated heavy ions on biological matter, the responses of spores of B. subtilis to this structured high LET radiation was investigated applying two different approaches. 1) By the use of the Biostack concept, the inactivation probability as a function of radial distance to single particles' trajectory (i.e. impact parameter) was determined in space experiments as well as at accelerators using low fluences of heavy ions. It was found that spores can survive even a central hit and that the effective range of inactivation extends far beyond impact parameters where inactivation by delta-ray dose would be effective. Concerning the space experiment, the inactivation cross section exceeds those from comparable accelerator experiments by roughly a factor of 20. 2) From fluence effect curves, cross sections for inactivation and mutation induction, and the efficiency of repair processes were determined. They are influenced by the ions characteristics in a complex manner. According to dependence on LET, at least 3 LET ranges can be differentiated: A low LET range (app. < 200 keV/micrometers), where cross sections for inactivation and mutation induction follow a common curve for different ions and where repair processes are effective; an intermediate LET range of the so-called saturation cross section with negligible mutagenic and repair efficiency; and a high LET range (>1000 keV/micrometers) where the biological endpoints are majorly dependent on atomic mass and energy of the ion under consideration.

Recent thymic emigrants are tolerized in the absence of inflammation.

PubMed

Friesen, Travis J; Ji, Qingyong; Fink, Pamela J

2016-05-30

T cell development requires a period of postthymic maturation. Why this is the case has remained a mystery, particularly given the rigors of intrathymic developmental checkpoints, successfully traversed by only ∼5% of thymocytes. We now show that the first few weeks of T cell residence in the lymphoid periphery define a period of heightened susceptibility to tolerance induction to tissue-restricted antigens (TRAs), the outcome of which depends on the context in which recent thymic emigrants (RTEs) encounter antigen. After encounter with TRAs in the absence of inflammation, RTEs exhibited defects in proliferation, diminished cytokine production, elevated expression of anergy-associated genes, and diminished diabetogenicity. These properties were mirrored in vitro by enhanced RTE susceptibility to regulatory T cell-mediated suppression. In the presence of inflammation, RTEs and mature T cells were, in contrast, equally capable of inducing diabetes, proliferating, and producing cytokines. Thus, recirculating RTEs encounter TRAs during a transitional developmental stage that facilitates tolerance induction, but inflammation converts antigen-exposed, tolerance-prone RTEs into competent effector cells. © 2016 Friesen et al.

Comparison of recirculation configurations for biological nutrient removal in a membrane bioreactor.

PubMed

Bekir Ersu, Cagatayhan; Ong, Say Kee; Arslankaya, Ertan; Brown, Patrick

2008-03-01

A 12-L lab-scale membrane bioreactor (MBR), consisting of an anaerobic and anoxic compartment followed by an oxic plate-frame membrane compartment, was evaluated for carbonaceous and nutrient removals by varying the recirculation of mixed liquor and permeate. The hydraulic retention times (HRTs) for the anaerobic, anoxic, and oxic compartments were 2, 2, and 8h, respectively. The solids residence time (SRT) for the oxic compartment was 25 days. Five different recirculation configurations were tested by recirculating mixed liquor and/or permeate recirculation equal to the influent flow rate (identified as 100%) into different locations of the anaerobic and anoxic compartments. Of the five configurations, the configuration with 100% mixed liquor recirculation to the anaerobic compartment and 100% permeate recirculation to the anoxic compartment gave the highest percentage removal with an average 92.3+/-0.5% soluble chemical oxygen demand (sCOD), 75.6+/-0.4% total nitrogen (TN), and 62.4+/-1.3% total phosphorus (TP) removal. When the mixed liquor and permeate recirculation rates were varied for the same configuration, the highest TP removal was obtained for 300% mixed liquor recirculation and 100% permeate recirculation (300%/100%) with a TP removal of 88.1+/-1.3% while the highest TN removal (90.3+/-0.3%) was obtained for 200%/300% recirculation. TN and TP concentrations as low as 4.2+/-0.1 and 1.4+/-0.2mg/L respectively were obtained. Mass loading rates were generally low in the range of 0.11-0.22kgCOD/kgMLSS/d due to high biomass concentrations within the oxic reactor (approx. 8000mg/L). The BioWin model was calibrated against one set of the experimental data and was found to predict the experimental data of effluent TN, TP, and NO(3)(-)-N but over-predicted sCOD and NH(3)-N for various recirculation rates. The anoxic heterotrophic yield for the calibrated model was 0.2kg biomass COD/kg COD utilized while the maximum growth rates were found to be 0.45day(-1) for mu(max-autotroph), 3.2day(-1) for mu(max-heterotroph), and 1.5day(-1) for mu(max-PAO).

Measuring ion velocity distribution functions through high-aspect ratio holes in inductively coupled plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cunge, G., E-mail: gilles.cunge@cea.fr; Darnon, M.; Dubois, J.

2016-02-29

Several issues associated with plasma etching of high aspect ratio structures originate from the ions' bombardment of the sidewalls of the feature. The off normal angle incident ions are primarily due to their temperature at the sheath edge and possibly to charging effects. We have measured the ion velocity distribution function (IVDF) at the wafer surface in an industrial inductively coupled plasma reactor by using multigrid retarding field analyzers (RFA) in front of which we place 400 μm thick capillary plates with holes of 25, 50, and 100 μm diameters. The RFA then probes IVDF at the exit of the holes withmore » Aspect Ratios (AR) of 16, 8, and 4, respectively. The results show that the ion flux dramatically drops with the increase in AR. By comparing the measured IVDF with an analytical model, we concluded that the ion temperature is 0.27 eV in our plasma conditions. The charging effects are also observed and are shown to significantly reduce the ion energy at the bottom of the feature but only with a “minor” effect on the ion flux and the shape of the IVDF.« less

Sulfur recirculation for increased electricity production in Waste-to-Energy plants.

PubMed

Andersson, Sven; Blomqvist, Evalena W; Bäfver, Linda; Jones, Frida; Davidsson, Kent; Froitzheim, Jan; Karlsson, Martin; Larsson, Erik; Liske, Jesper

2014-01-01

Sulfur recirculation is a new technology for reducing boiler corrosion and dioxin formation. It was demonstrated in full-scale tests at a Waste to Energy plant in Göteborg (Sweden) during nearly two months of operation. Sulfur was recirculated as sulfuric acid from the flue gas cleaning back to the boiler, thus creating a sulfur loop. The new technology was evaluated by extensive measurement campaigns during operation under normal conditions (reference case) and operation with sulfur recirculation. The chlorine content of both fly ash and boiler ash decreased and the sulfur content increased during the sulfur recirculation tests. The deposit growth and the particle concentration decreased with sulfur recirculation and the dioxin concentration (I-TEQ) of the flue gas was reduced by approximately 25%. Sulfuric acid dew point measurements showed that the sulfuric acid dosage did not lead to elevated SO3 concentrations, which may otherwise induce low temperature corrosion. In the sulfur recirculation corrosion probe exposures, the corrosion rate decreased for all tested materials (16Mo3, Sanicro 28 and Inconel 625) and material temperatures (450 °C and 525 °C) compared to the reference exposure. The corrosion rates were reduced by 60-90%. Sulfur recirculation prevented the formation of transition metal chlorides at the metal/oxide interface, formation of chromate and reduced the presence of zinc in the corrosion products. Furthermore, measured corrosion rates at 525 °C with sulfur recirculation in operation were similar or lower compared to those measured at 450 °C material temperature in reference conditions, which corresponds to normal operation at normal steam temperatures. This implies that sulfur recirculation allows for higher steam data and electricity production without increasing corrosion. Copyright © 2013 The Authors. Published by Elsevier Ltd.. All rights reserved.

Bulk plasma fragmentation in a C4F8 inductively coupled plasma: A hybrid modeling study

NASA Astrophysics Data System (ADS)

Zhao, Shu-Xia; Zhang, Yu-Ru; Gao, Fei; Wang, You-Nian; Bogaerts, Annemie

2015-06-01

A hybrid model is used to investigate the fragmentation of C4F8 inductive discharges. Indeed, the resulting reactive species are crucial for the optimization of the Si-based etching process, since they determine the mechanisms of fluorination, polymerization, and sputtering. In this paper, we present the dissociation degree, the density ratio of F vs. CxFy (i.e., fluorocarbon (fc) neutrals), the neutral vs. positive ion density ratio, details on the neutral and ion components, and fractions of various fc neutrals (or ions) in the total fc neutral (or ion) density in a C4F8 inductively coupled plasma source, as well as the effect of pressure and power on these results. To analyze the fragmentation behavior, the electron density and temperature and electron energy probability function (EEPF) are investigated. Moreover, the main electron-impact generation sources for all considered neutrals and ions are determined from the complicated C4F8 reaction set used in the model. The C4F8 plasma fragmentation is explained, taking into account many factors, such as the EEPF characteristics, the dominance of primary and secondary processes, and the thresholds of dissociation and ionization. The simulation results are compared with experiments from literature, and reasonable agreement is obtained. Some discrepancies are observed, which can probably be attributed to the simplified polymer surface kinetics assumed in the model.

Calculation of recirculating flow behind flame-holders

NASA Astrophysics Data System (ADS)

Zeng, Q.; Sheng, Y.; Zhou, Q.

1985-10-01

Adoptability of standard K-epsilon turbulence model for numerical calculation of recirculating flow is discussed. Many computations of recirculating flows behind bluff-bodies used as flame-holders in afterburner of aeroengine have been completed. Blocking-off method to treat the incline walls of the flame-holder gives good results. In isothermal recirculating flows the flame-holder wall is assumed to be isolated. Therefore, it is possible to remove the inactive zone from the calculation domain in programming to save computer time. The computation for a V-shaped flame-holder exhibits an interesting phenomenon that the recirculation zone extends to the cavity of the flame-holder.

High-precision determination of {sup 234}U/{sup 238}U activity ratios in natural waters and carbonates by ICPMS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ketterer, M.E.; Khourey, C.J.

1998-12-31

A method has been developed for precise measurement of {sup 234}U/{sup 238}U activity ratios in natural waters and carbonates using quadrupole inductively coupled plasma mass spectrometry. A recovery of 80--85% of seawater U is achieved by Fe(III) coprecipitation followed by extraction chromatography with a supported dipentyl pentane phosphonate material; 90--95% of U is recovered from carbonates, which are dissolved in HNO{sub 3} and subjected to the same extraction chromatographic preparation. Isotopic measurements are made via recirculating pneumatic nebulization of small volumes of solutions containing 0.5--5 mg/L U. {sup 234}U/{sup 235}U is measured as a proxy for determination of {sup 234}U/{supmore » 238}U; iridium is added to sample solutions and the ion ratio {sup 191}Ir{sup 40}Ar{sup +}/{sup 193}Ir{sup 40}Ar{sup +} is measured for internal mass discrimination correction {sup 234}U/{sup 238}U activity ratios in the range 1.143--1.154 are observed for 13 seawater and contemporary corals, in agreement with the established marine {sup 234}U/{sup 238}U activity ratio. For samples sizes of 5--25 {micro}g U, ICPMS uncertainties of {+-} 0.2--0.5% relative, 2{theta} standard error, approach those obtained for < 0.1 {micro}g U by thermal ionization mass spectrometry. Measurements of {sup 234}U/{sup 238}U activity ratios in bottled waters, Lake Erie surface waters, mollusk fossils, and fertilizers are also demonstrated.« less

Anolyte recirculation effects in buffered and unbuffered single-chamber air-cathode microbial fuel cells.

PubMed

Zhang, Liang; Zhu, Xun; Kashima, Hiroyuki; Li, Jun; Ye, Ding-Ding; Liao, Qiang; Regan, John M

2015-03-01

Two identical microbial fuel cells (MFCs) with a floating air-cathode were operated under either buffered (MFC-B) or bufferless (MFC-BL) conditions to investigate anolyte recirculation effects on enhancing proton transfer. With an external resistance of 50 Ω and recirculation rate of 1.0 ml/min, MFC-BL had a 27% lower voltage (9.7% lower maximal power density) but a 64% higher Coulombic efficiency (CE) than MFC-B. MFC-B had a decreased voltage output, batch time, and CE with increasing recirculation rate resulting from more oxygen transfer into the anode. However, increasing the recirculation rate within a low range significantly enhanced proton transfer in MFC-BL, resulting in a higher voltage output, a longer batch time, and a higher CE. A further increase in recirculation rate decreased the batch time and CE of MFC-BL due to excess oxygen transfer into anode outweighing the proton-transfer benefits. The unbuffered MFC had an optimal recirculation rate of 0.35 ml/min. Copyright © 2014 Elsevier Ltd. All rights reserved.

10 W single-mode Er/Yb co-doped all-fiber amplifier with suppressed Yb-ASE

NASA Astrophysics Data System (ADS)

Sobon, G.; Sliwinska, D.; Abramski, K. M.; Kaczmarek, P.

2014-02-01

In this work we demonstrate a single-frequency, single-mode all-fiber master oscillator power amplifier (MOPA) source, based on erbium-ytterbium co-doped double-clad fiber emitting 10 W of continuous wave power at 1565 nm. In the power amplifier stage, the amplified spontaneous emission from Yb3+ ions (Yb-ASE) is forced to recirculate in a loop resonator in order to provide stable lasing at 1060 nm. The generated signal acts as an additional pump source for the amplifier and is reabsorbed by the Yb3+ ions in the active fiber, allowing an increase in the efficiency and boosting the output power. The feedback loop also protects the amplifier from parasitic lasing or self-pulsing at a wavelength of 1 μm. This allows one to significantly scale the output power in comparison to a conventional setup without any Yb-ASE control.

TRANSIENT BEAM LOADING EFFECTS IN RF SYSTEMS IN JLEIC

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Haipeng; Guo, Jiquan; Rimmer, Robert A.

2016-05-01

The pulsed electron bunch trains generated from the Continuous Electron Beam Accelerator Facility (CEBAF) linac to inject into the proposed Jefferson Lab Electron Ion Collider (JLEIC) e-ring will produce transient beam loading effects in the Superconducting Radio Frequency (SRF) systems that, if not mitigated, could cause unacceptably large beam energy deviation in the injection capture, or exceed the energy acceptance of CEBAF’s recirculating arcs. In the electron storage ring, the beam abort or ion clearing gaps or uneven bucket filling can cause large beam phase transients in the (S)RF cavity control systems and even beam loss due to Robinson instability.more » We have first analysed the beam stability criteria in steady state and estimated the transient effect in Feedforward and Feedback RF controls. Initial analytical models for these effects are shown for the design of the JLEIC e-ring from 3GeV to 12GeV.« less

Effects of a chirped bias voltage on ion energy distributions in inductively coupled plasma reactors

NASA Astrophysics Data System (ADS)

Lanham, Steven J.; Kushner, Mark J.

2017-08-01

The metrics for controlling reactive fluxes to wafers for microelectronics processing are becoming more stringent as feature sizes continue to shrink. Recent strategies for controlling ion energy distributions to the wafer involve using several different frequencies and/or pulsed powers. Although effective, these strategies are often costly or present challenges in impedance matching. With the advent of matching schemes for wide band amplifiers, other strategies to customize ion energy distributions become available. In this paper, we discuss results from a computational investigation of biasing substrates using chirped frequencies in high density, electronegative inductively coupled plasmas. Depending on the frequency range and chirp duration, the resulting ion energy distributions exhibit components sampled from the entire frequency range. However, the chirping process also produces transient shifts in the self-generated dc bias due to the reapportionment of displacement and conduction with frequency to balance the current in the system. The dynamics of the dc bias can also be leveraged towards customizing ion energy distributions.

Separation of silver ions and starch modified silver nanoparticles using high performance liquid chromatography with ultraviolet and inductively coupled mass spectrometric detection

NASA Astrophysics Data System (ADS)

Hanley, Traci A.; Saadawi, Ryan; Zhang, Peng; Caruso, Joseph A.; Landero-Figueroa, Julio

2014-10-01

The production of commercially available products marketed to contain silver nanoparticles is rapidly increasing. Species-specific toxicity is a phenomenon associated with many elements, including silver, making it imperative to develop a method to identify and quantify the various forms of silver (namely, silver ions vs. silver nanoparticles) possibly present in these products. In this study a method was developed using high performance liquid chromatography (HPLC) with ultraviolet (UV-VIS) and inductively coupled mass spectrometric (ICP-MS) detection to separate starch stabilized silver nanoparticles (AgNPs) and silver ions (Ag+) by cation exchange chromatography with 0.5 M nitric acid mobile phase. The silver nanoparticles and ions were baseline resolved with an ICP-MS response linear over four orders of magnitude, 0.04 mg kg- 1 detection limit, and 90% chromatographic recovery for silver solutions containing ions and starch stabilized silver nanoparticles smaller than 100 nm.

Heavy ion action on yeast cells: Inhibition of ribosomal-RNA synthesis, loss of colony forming ability and induction of mutants

NASA Astrophysics Data System (ADS)

Kiefer, J.; Rase, S.; Schöpfer, F.; Schneider, E.; Weber, K.; Kraft, G.

The action of heavy ions (Ar to U) accelerated to specific energies up to about 10 MeV/u (u=atomic mass unit) on different functions of yeast cells was studied. Ribosomal-RNA synthesis is inhibited according to a single-hit mechanism. Inactivation cross-sections were linearly related to the ratio of the squares of the effective charge Z* and the velocity of the ions. It is concluded from the analysis that the range of the most energetic δ-electrons is larger than previously assumed. There is no such dependence for survival and induction of mutants. In both cases cross-sections increase with the ion's specific-energy indicating an important contribution of long-range δ-electrons. The analysis shows that diploid yeast is not killed by a single-hit mechanism even by very heavy ions if the track width is too small. The relative importance of the penumbral region is even more pronounced with the more sensitive strains.

40 CFR 98.468 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... applicable climate classification is determined based on the annual rainfall plus the recirculated leachate... [with appropriate unit conversions]. (1) Dry climate = precipitation plus recirculated leachate less than 20 inches/year. (2) Moderate climate = precipitation plus recirculated leachate from 20 to 40...

Numerical analysis of biomass torrefaction reactor with recirculation of heat carrier

NASA Astrophysics Data System (ADS)

Director, L. B.; Ivanin, O. A.; Sinelshchikov, V. A.

2018-01-01

In this paper, results of numerical analysis of the energy-technological complex consisting of the gas piston power plant, the torrefaction reactor with recirculation of gaseous heat carrier and the heat recovery boiler are presented. Calculations of the reactor without recirculation and with recirculation of the heat carrier in torrefaction zone at different frequencies of unloading of torrefied biomass were held. It was shown that in recirculation mode the power of the gas piston power plant, required for providing given reactor productivity, is reduced several times and the consumption of fuel gas, needed for combustion of volatile torrefaction products in the heat recovery boiler, is reduced by an order.

Exhaust gas recirculation in a homogeneous charge compression ignition engine

DOEpatents

Duffy, Kevin P [Metamora, IL; Kieser, Andrew J [Morton, IL; Rodman, Anthony [Chillicothe, IL; Liechty, Michael P [Chillicothe, IL; Hergart, Carl-Anders [Peoria, IL; Hardy, William L [Peoria, IL

2008-05-27

A homogeneous charge compression ignition engine operates by injecting liquid fuel directly in a combustion chamber, and mixing the fuel with recirculated exhaust and fresh air through an auto ignition condition of the fuel. The engine includes at least one turbocharger for extracting energy from the engine exhaust and using that energy to boost intake pressure of recirculated exhaust gas and fresh air. Elevated proportions of exhaust gas recirculated to the engine are attained by throttling the fresh air inlet supply. These elevated exhaust gas recirculation rates allow the HCCI engine to be operated at higher speeds and loads rendering the HCCI engine a more viable alternative to a conventional diesel engine.

Flow field in the wake of a bluff body driven through a steady recirculating flow

NASA Astrophysics Data System (ADS)

Poussou, Stephane B.; Plesniak, Michael W.

2015-02-01

The wake produced by a bluff body driven through a steady recirculating flow is studied experimentally in a water facility using particle image velocimetry. The bluff body has a rectangular cross section of height, , and width, , such that the aspect ratio, AR = H/ D, is equal to 3. The motion of the bluff body is uniform and rectilinear, and corresponds to a Reynolds number based on width, Re D = 9,600. The recirculating flow is confined within a hemicylindrical enclosure and is generated by planar jets emanating from slots of width, , such that . Under these conditions, experiments are performed in a closed-loop facility that enables complete optical access to the near-wake. Velocity fields are obtained up to a distance of downstream of the moving body. Data include a selection of phase-averaged velocity fields representative of the wake for a baseline case (no recirculation) and an interaction case (with recirculation). Results indicate that the transient downwash flow typically observed in wakes behind finite bodies of small aspect ratio is significantly perturbed by the recirculating flow. The wake is displaced from the ground plane and exhibits a shorter recirculation zone downstream of the body. In summary, it was found that the interaction between a bluff body wake and a recirculating flow pattern alters profoundly the dynamics of the wake, which has implications on scalar transport in the wake.

Automation of water supply and recirculation-filtration of water at a swimming pool using Zelio PLC

NASA Astrophysics Data System (ADS)

Diniş, C. M.; Popa, G. N.; Iagăr, A.

2018-01-01

The paper proposes the use of the Zelio PLC for the automation of the water supply and recirculation-filtration system of a swimming pool. To do this, the Zelio SR3B261BD - 24V DC with 10 digital inputs (24V DC) and 10 digital outputs (relay contacts) was used. The proposed application makes the control of the water supply pumps and the water recirculation-filtration from a swimming pool. The recirculation-filtration systems for pools and swimming pools are designed to ensure water cleaning and recirculation to achieve optimum quality and lasting service life. The water filtration process is one of the important steps in water treatment in polls and swimming pools. It consists in recirculation of the entire volume of water and begins by absorbing the water in the pool by means of a pump followed by the passing of water through the filter, disinfectant and pH dosing, and reintroducing the water back into the pool or swimming pool through the discharge holes. Filters must to work 24 hours a day to remove pollutants from pools or swimming pools users. Filtration removes suspension particles with different origins. All newly built pools and swimming pools must be fitted with water recirculation systems, and existing ones will be equipped with water recirculation and water treatment systems.

Method of processing materials using an inductively coupled plasma

DOEpatents

Hull, Donald E.; Bieniewski, Thomas M.

1989-01-01

A method for coating surfaces or implanting ions in an object using an inductively coupled plasma. The method provides a gas-free environment, since the plasma is formed without using a gas. The coating material or implantation material is intitially in solid form.

Simulation of RF power and multi-cusp magnetic field requirement for H- ion sources

NASA Astrophysics Data System (ADS)

Pathak, Manish; Senecha, V. K.; Kumar, Rajnish; Ghodke, Dharmraj. V.

2016-12-01

A computer simulation study for multi-cusp RF based H- ion source has been carried out using energy and particle balance equation for inductively coupled uniformly dense plasma considering sheath formation near the boundary wall of the plasma chamber for RF ion source used as high current injector for 1 Gev H- Linac project for SNS applications. The average reaction rates for different reactions responsible for H- ion production and destruction have been considered in the simulation model. The RF power requirement for the caesium free H- ion source for a maximum possible H- ion beam current has been derived by evaluating the required current and RF voltage fed to the coil antenna using transformer model for Inductively Coupled Plasma (ICP). Different parameters of RF based H- ion source like excited hydrogen molecular density, H- ion density, RF voltage and current of RF antenna have been calculated through simulations in the presence and absence of multicusp magnetic field to distinctly observe the effect of multicusp field. The RF power evaluated for different H- ion current values have been compared with the experimental reported results showing reasonably good agreement considering the fact that some RF power will be reflected from the plasma medium. The results obtained have helped in understanding the optimum field strength and field free regions suitable for volume emission based H- ion sources. The compact RF ion source exhibits nearly 6 times better efficiency compare to large diameter ion source.

The impact of recirculating industrial air on aircraft painting operations.

PubMed

LaPuma, P T; Bolch, W E

1999-10-01

The 1990 Clean Air Act Amendments resulted in new environmental regulations for hazardous air pollutants. Industries such as painting facilities may have to treat large volumes of air, which increases the cost of an air control system. Recirculating a portion of the air back into the facility is an option to reduce the amount of air to be treated. The authors of this study developed a computer model written in Microsoft Excel 97 to analyze the impact of recirculation on worker safety and compliance costs. The model has a chemical database with over 1300 chemicals. The model will predict indoor air concentrations using mass balance calculations and results are compared to occupational exposure limits. A case study is performed on a C-130 aircraft painting facility at Hill Air Force Base, Utah. The model predicts strontium chromate concentrations found in primer paints will reach 1000 times the exposure limit. Strontium chromate and other solid particulates are nearly unaffected by recirculation because the air is filtered during recirculation. The next highest chemical, hexamethylene diisocyanate, increases from 2.6 to 10.5 times the exposure limit at 0 percent and 75 percent recirculation, respectively. Due to the level of respiratory protection required for the strontium chromate, workers are well protected from the modest increases in concentrations caused by recirculating 75 percent of the air. The initial cost of an air control system is $4.5 million with no recirculation and $1.8 million at 75 percent recirculation. The model is an excellent tool to evaluate air control options with a focus on worker safety. In the case study, the model highlights strontium chromate primers as good candidates for substitution. The model shows that recirculating 75 percent of the air at the Hill painting facility has a negligible impact on safety and could save $2.7 million on the initial expenses of a thermal treatment system.

Enhanced leachate recirculation and stabilization in a pilot landfill bioreactor in Taiwan.

PubMed

Huang, Fu-Shih; Hung, Jui-Min; Lu, Chih-Jen

2012-08-01

This study focused on the treatment of municipal solid waste (MSW) by modification and recirculation of leachate from a simulated landfill bioreactor. Hydrogen peroxide was added to recirculated leachate to maintain a constant oxygen concentration as the leachate passed again through the simulated landfill bioreactor. The results showed that leachate recirculation increased the dissolved oxygen concentration in the test landfill bioreactor. Over a period of 405 days, the biochemical oxygen demand (BOD(5)) in the collected leachate reduced by 99.7%, whereas the chemical oxygen demand (COD) reduced by 96%. The BOD(5)/COD ratio at the initial stage of 0.9 improved to 0.09 under aerobic conditions (leachate recirculation with added hydrogen peroxide) compared with the anaerobic test cell 0.11 (leachate recirculation alone without hydrogen peroxide). The pH increased from 5.5 to 7.6, and the degradation rate of organic carbon was 93%. Leachate recirculation brings about the biodegradation of MSW comparatively faster than the conventional landfill operation. The addition of a constant concentration of hydrogen peroxide was found to further increase the biodegradation. This increased biodegradation rate ultimately enables an MSW landfill to reach a stable state sooner and free up the land for further reuse.

Non-Targeted Effects and the Dose Response for Heavy Ion Tumorigenesis

NASA Technical Reports Server (NTRS)

Chappell, Lori J.; Cucinotta, Francis A.

2010-01-01

There is no human epidemiology data available to estimate the heavy ion cancer risks experienced by astronauts in space. Studies of tumor induction in mice are a necessary step to estimate risks to astronauts. Previous experimental data can be better utilized to model dose response for heavy ion tumorigenesis and plan future low dose studies.

Low-head saltwater recirculating aquaculture systems utilized for juvenile red drum production

USDA-ARS?s Scientific Manuscript database

Recirculating aquaculture systems reuse water with mechanical and biological treatment between each use and thus require wastewater treatment techniques for continuous waste removal. However, the traditional techniques and equipment utilized in recirculating aquaculture systems are expensive. The d...

Recirculating Aquaculture (4th edition)

USDA-ARS?s Scientific Manuscript database

Typically recirculating (closed) aquatic production systems have higher capital and operating costs than many of the extensive systems such as cage culture in natural waters and raceway and/or pond culture systems. However, when the control provided by recirculating systems and the benefits this env...

40 CFR 1065.127 - Exhaust gas recirculation.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 34 2012-07-01 2012-07-01 false Exhaust gas recirculation. 1065.127 Section 1065.127 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING PROCEDURES Equipment Specifications § 1065.127 Exhaust gas recirculation. Use the...

40 CFR 1065.127 - Exhaust gas recirculation.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 33 2011-07-01 2011-07-01 false Exhaust gas recirculation. 1065.127 Section 1065.127 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING PROCEDURES Equipment Specifications § 1065.127 Exhaust gas recirculation. Use the...

40 CFR 1065.127 - Exhaust gas recirculation.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Exhaust gas recirculation. 1065.127 Section 1065.127 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING PROCEDURES Equipment Specifications § 1065.127 Exhaust gas recirculation. Use the...

40 CFR 1065.127 - Exhaust gas recirculation.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 34 2013-07-01 2013-07-01 false Exhaust gas recirculation. 1065.127 Section 1065.127 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING PROCEDURES Equipment Specifications § 1065.127 Exhaust gas recirculation. Use the...

40 CFR 1065.127 - Exhaust gas recirculation.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 33 2014-07-01 2014-07-01 false Exhaust gas recirculation. 1065.127 Section 1065.127 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING PROCEDURES Equipment Specifications § 1065.127 Exhaust gas recirculation. Use the...

Demonstration of Split-Flow Ventilation and Recirculation as Flow- Reduction Methods in an Air Force Paint Spray Booth. Volume 1

DTIC Science & Technology

1994-07-27

of the split-flow and recirculation modifications in typical Air Force painting operations; itwas a proof-of- concept study only. It is recognized...recirculating ventilation. 4 To Implement this flow-reduction concept , it must first be established that recirculation does not cause an accumulation of toxic...ventilation concept . The concentration gradient is determined by height and direction of paint application. If the concentration in the top portion is

Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells.

PubMed

Watanabe, Rei; Gehad, Ahmed; Yang, Chao; Scott, Laura L; Teague, Jessica E; Schlapbach, Christoph; Elco, Christopher P; Huang, Victor; Matos, Tiago R; Kupper, Thomas S; Clark, Rachael A

2015-03-18

The skin of an adult human contains about 20 billion memory T cells. Epithelial barrier tissues are infiltrated by a combination of resident and recirculating T cells in mice, but the relative proportions and functional activities of resident versus recirculating T cells have not been evaluated in human skin. We discriminated resident from recirculating T cells in human-engrafted mice and lymphoma patients using alemtuzumab, a medication that depletes recirculating T cells from skin, and then analyzed these T cell populations in healthy human skin. All nonrecirculating resident memory T cells (TRM) expressed CD69, but most were CD4(+), CD103(-), and located in the dermis, in contrast to studies in mice. Both CD4(+) and CD8(+) CD103(+) TRM were enriched in the epidermis, had potent effector functions, and had a limited proliferative capacity compared to CD103(-) TRM. TRM of both types had more potent effector functions than recirculating T cells. We observed two distinct populations of recirculating T cells, CCR7(+)/L-selectin(+) central memory T cells (TCM) and CCR7(+)/L-selectin(-) T cells, which we term migratory memory T cells (TMM). Circulating skin-tropic TMM were intermediate in cytokine production between TCM and effector memory T cells. In patients with cutaneous T cell lymphoma, malignant TCM and TMM induced distinct inflammatory skin lesions, and TMM were depleted more slowly from skin after alemtuzumab, suggesting that TMM may recirculate more slowly. In summary, human skin is protected by four functionally distinct populations of T cells, two resident and two recirculating, with differing territories of migration and distinct functional activities. Copyright © 2015, American Association for the Advancement of Science.

Effects of leachate recirculation on biogas production from landfill co-disposal of municipal solid waste, sewage sludge and marine sediment.

PubMed

Chan, G Y S; Chu, L M; Wong, M H

2002-01-01

Leachate recirculation is an emerging technology associated with the management of landfill. The impact of leachate recirculation on the co-disposal of three major wastes (municipal solid waste, sewage sludge and sediment dredgings) was investigated using a laboratory column study. Chemical parameters (pH, COD, ammoniacal-N, total-P) and gas production (total gas volume, production rates and concentrations of CH4 and CO2) were monitored for 11 weeks. Leachate recirculation reduced waste-stabilization time and was effective in enhancing gas production and improving leachate quality, especially in terms of COD. The results also indicated that leachate recirculation could maximize the efficiency and waste volume reduction rate of landfill sites.

Power plant including an exhaust gas recirculation system for injecting recirculated exhaust gases in the fuel and compressed air of a gas turbine engine

DOEpatents

Anand, Ashok Kumar; Nagarjuna Reddy, Thirumala Reddy; Shaffer, Jason Brian; York, William David

2014-05-13

A power plant is provided and includes a gas turbine engine having a combustor in which compressed gas and fuel are mixed and combusted, first and second supply lines respectively coupled to the combustor and respectively configured to supply the compressed gas and the fuel to the combustor and an exhaust gas recirculation (EGR) system to re-circulate exhaust gas produced by the gas turbine engine toward the combustor. The EGR system is coupled to the first and second supply lines and configured to combine first and second portions of the re-circulated exhaust gas with the compressed gas and the fuel at the first and second supply lines, respectively.

Modeling of leachate recirculation using combined drainage blanket-horizontal trench systems in bioreactor landfills.

PubMed

Feng, Shi-Jin; Cao, Ben-Yi; Xie, Hai-Jian

2017-10-01

Leachate recirculation in municipal solid waste (MSW) landfills operated as bioreactors offers significant economic and environmental benefits. Combined drainage blanket (DB)-horizontal trench (HT) systems can be an alternative to single conventional recirculation approaches and can have competitive advantages. The key objectives of this study are to investigate combined drainage blanket -horizontal trench systems, to analyze the effects of applying two recirculation systems on the leachate migration in landfills, and to estimate some key design parameters (e.g., the steady-state flow rate, the influence width, and the cumulative leachate volume). It was determined that an effective recirculation model should consist of a moderate horizontal trench injection pressure head and supplementary leachate recirculated through drainage blanket, with an objective of increasing the horizontal unsaturated hydraulic conductivity and thereby allowing more leachate to flow from the horizontal trench system in a horizontal direction. In addition, design charts for engineering application were established using a dimensionless variable formulation.

Define of internal recirculation coefficient for biological wastewater treatment in anoxic and aerobic bioreactors

NASA Astrophysics Data System (ADS)

Rossinskyi, Volodymyr

2018-02-01

The biological wastewater treatment technologies in anoxic and aerobic bioreactors with recycle of sludge mixture are used for the effective removal of organic compounds from wastewater. The change rate of sludge mixture recirculation between bioreactors leads to a change and redistribution of concentrations of organic compounds in sludge mixture in bioreactors and change hydrodynamic regimes in bioreactors. Determination of the coefficient of internal recirculation of sludge mixture between bioreactors is important for the choice of technological parameters of biological treatment (wastewater treatment duration in anoxic and aerobic bioreactors, flow capacity of recirculation pumps). Determination of the coefficient of internal recirculation of sludge mixture requires integrated consideration of hydrodynamic parameter (flow rate), kinetic parameter (rate of oxidation of organic compounds) and physical-chemical parameter of wastewater (concentration of organic compounds). The conducted numerical experiment from the proposed mathematical equations allowed to obtain analytical dependences of the coefficient of internal recirculation sludge mixture between bioreactors on the concentration of organic compounds in wastewater, the duration of wastewater treatment in bioreactors.

Numerical study of the inductive plasma coupling to ramp up the plasma density for the Linac4 H- ion source

NASA Astrophysics Data System (ADS)

Ohta, M.; Mattei, S.; Yasumoto, M.; Hatayama, A.; Lettry, J.

2014-02-01

In the Linac4 H- ion source, the plasma is generated by an RF antenna operated at 2 MHz. In order to investigate the conditions necessary for ramping up the plasma density of the Linac4 H- ion source in the low plasma density, a numerical study has been performed for a wide range of parameter space of RF coil current and initial pressure from H2 gas injection. We have employed an Electromagnetic Particle in Cell model, in which the collision processes have been calculated by a Monte Carlo method. The results have shown that the range of initial gas pressure from 2 to 3 Pa is suitable for ramping up plasma density via inductive coupling.

Ion Heating During Local Helicity Injection Plasma Startup in the Pegasus ST

NASA Astrophysics Data System (ADS)

Burke, M. G.; Barr, J. L.; Bongard, M. W.; Fonck, R. J.; Hinson, E. T.; Perry, J. M.; Reusch, J. A.

2015-11-01

Plasmas in the Pegasus ST are initiated either through standard, MHD stable, inductive current drive or non-solenoidal local helicity injection (LHI) current drive with strong reconnection activity, providing a rich environment to study ion dynamics. During LHI discharges, a large amount of impurity ion heating has been observed, with the passively measured impurity Ti as high as 800 eV compared to Ti ~ 60 eV and Te ~ 175 eV during standard inductive current drive discharges. In addition, non-thermal ion velocity distributions are observed and appear to be strongest near the helicity injectors. The ion heating is hypothesized to be a result of large-scale magnetic reconnection activity, as the amount of heating scales with increasing fluctuation amplitude of the dominant, edge localized, n =1 MHD mode. An approximate temporal scaling of the heating with the amplitude of higher frequency magnetic fluctuations has also been observed, with large amounts of power spectral density present at several impurity ion cyclotron frequencies. Recent experiments have focused on investigating the impurity ion heating scaling with the ion charge to mass ratio as well as the reconnecting field strength. The ion charge to mass ratio was modified by observing different impurity charge states in similar LHI plasmas while the reconnecting field strength was modified by changing the amount of injected edge current. Work supported by US DOE grant DE-FG02-96ER54375.

Triboelectric, Corona, and Induction Charging of Insulators as a Function of Pressure

NASA Technical Reports Server (NTRS)

Hogue, Michael D.; Mucciolo, Eduardo R.; Calle, Carlos I.

2006-01-01

Theoretical and experimental research has been performed that shows that the surface charge on an insulator after triboelectric charging with another insulator is rapidly dissipated with lowered atmospheric pressure. This pressure discharge is consistent with surface ions being evaporated off the surface once their vapor pressure is attained. In this paper we will report on the results of three different charging techniques (triboelectric, corona, and induction) performed on selected polymers with varying atmospheric pressure. This data will show that ion exchange between the polymer samples is the mechanism responsible for most of the surface charge on the polymer surfaces.

Ionotropic NMDA receptor signaling is required for the induction of long-term depression in the mouse hippocampal CA1 region.

PubMed

Babiec, Walter E; Guglietta, Ryan; Jami, Shekib A; Morishita, Wade; Malenka, Robert C; O'Dell, Thomas J

2014-04-09

Previous studies have provided strong support for the notion that NMDAR-mediated increases in postsynaptic Ca(2+) have a crucial role in the induction of long-term depression (LTD). This view has recently been challenged, however, by findings suggesting that LTD induction is instead attributable to an ion channel-independent, metabotropic form of NMDAR signaling. Thus, to explore the role of ionotropic versus metabotropic NMDAR signaling in LTD, we examined the effects of varying extracellular Ca(2+) levels or blocking NMDAR channel ion fluxes with MK-801 on LTD and NMDAR signaling in the mouse hippocampal CA1 region. We find that the induction of LTD in the adult hippocampus is highly sensitive to extracellular Ca(2+) levels and that MK-801 blocks NMDAR-dependent LTD in the hippocampus of both adult and immature mice. Moreover, MK-801 inhibits NMDAR-mediated activation of p38-MAPK and dephosphorylation of AMPAR GluA1 subunits at sites implicated in LTD. Thus, our results indicate that the induction of LTD in the hippocampal CA1 region is dependent on ionotropic, rather than metabotropic, NMDAR signaling.

33 CFR 159.127 - Safety coliform count: Recirculating devices.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Safety coliform count....127 Safety coliform count: Recirculating devices. Thirty-eight of forty samples of flush fluid from a recirculating device must have less than 240 fecal coliform bacteria per 100 milliliters. These samples must be...

Recirculating rotary gas compressor

DOEpatents

Weinbrecht, John F.

1992-01-01

A positive displacement, recirculating Roots-type rotary gas compressor which operates on the basis of flow work compression. The compressor includes a pair of large diameter recirculation conduits (24 and 26) which return compressed discharge gas to the compressor housing (14), where it is mixed with low pressure inlet gas, thereby minimizing adiabatic heating of the gas. The compressor includes a pair of involutely lobed impellers (10 and 12) and an associated port configuration which together result in uninterrupted flow of recirculation gas. The large diameter recirculation conduits equalize gas flow velocities within the compressor and minimize gas flow losses. The compressor is particularly suited to applications requiring sustained operation at higher gas compression ratios than have previously been feasible with rotary pumps, and is particularly applicable to refrigeration or other applications requiring condensation of a vapor.

Engine with pulse-suppressed dedicated exhaust gas recirculation

DOEpatents

Keating, Edward J.; Baker, Rodney E.

2016-06-07

An engine assembly includes an intake assembly, a spark-ignited internal combustion engine, and an exhaust assembly. The intake assembly includes a charge air cooler disposed between an exhaust gas recirculation (EGR) mixer and a backpressure valve. The charge air cooler has both an inlet and an outlet, and the back pressure valve is configured to maintain a minimum pressure difference between the inlet of the charge air cooler and an outlet of the backpressure valve. A dedicated exhaust gas recirculation system is provided in fluid communication with at least one cylinder and with the EGR mixer. The dedicated exhaust gas recirculation system is configured to route all of the exhaust gas from the at least one cylinder to the EGR mixer for recirculation back to the engine.

Recirculating rotary gas compressor

DOEpatents

Weinbrecht, J.F.

1992-02-25

A positive displacement, recirculating Roots-type rotary gas compressor is described which operates on the basis of flow work compression. The compressor includes a pair of large diameter recirculation conduits which return compressed discharge gas to the compressor housing, where it is mixed with low pressure inlet gas, thereby minimizing adiabatic heating of the gas. The compressor includes a pair of involutely lobed impellers and an associated port configuration which together result in uninterrupted flow of recirculation gas. The large diameter recirculation conduits equalize gas flow velocities within the compressor and minimize gas flow losses. The compressor is particularly suited to applications requiring sustained operation at higher gas compression ratios than have previously been feasible with rotary pumps, and is particularly applicable to refrigeration or other applications requiring condensation of a vapor. 12 figs.

Cluster formation and drag reduction-proposed mechanism of particle recirculation within the partition column of the bottom spray fluid-bed coater.

PubMed

Wang, Li Kun; Heng, Paul Wan Sia; Liew, Celine Valeria

2015-04-01

Bottom spray fluid-bed coating is a common technique for coating multiparticulates. Under the quality-by-design framework, particle recirculation within the partition column is one of the main variability sources affecting particle coating and coat uniformity. However, the occurrence and mechanism of particle recirculation within the partition column of the coater are not well understood. The purpose of this study was to visualize and define particle recirculation within the partition column. Based on different combinations of partition gap setting, air accelerator insert diameter, and particle size fraction, particle movements within the partition column were captured using a high-speed video camera. The particle recirculation probability and voidage information were mapped using a visiometric process analyzer. High-speed images showed that particles contributing to the recirculation phenomenon were behaving as clustered colonies. Fluid dynamics analysis indicated that particle recirculation within the partition column may be attributed to the combined effect of cluster formation and drag reduction. Both visiometric process analysis and particle coating experiments showed that smaller particles had greater propensity toward cluster formation than larger particles. The influence of cluster formation on coating performance and possible solutions to cluster formation were further discussed. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

Effects of recirculation in a three-tank pilot-scale system for pharmaceutical removal with powdered activated carbon.

PubMed

Kårelid, Victor; Larsson, Gen; Björlenius, Berndt

2017-05-15

The removal of pharmaceutically active compounds by powdered activated carbon (PAC) in municipal wastewater is a promising solution to the problem of polluted recipient waters. Today, an efficient design strategy is however lacking with regard to high-level overall, and specific, substance removal in the large scale. The performance of PAC-based removal of pharmaceuticals was studied in pilot-scale with respect to the critical parameters; contact time and PAC dose using one PAC product selected by screening in bench-scale. The goal was a minimum of 95% removal of the pharmaceuticals present in the evaluated municipal wastewater. A set of 21 pharmaceuticals was selected from an initial 100 due to their high occurrence in the effluent water of two selected wastewater treatment plants (WWTPs) in Sweden, whereof candidates discussed for future EU regulation directives were included. By using recirculation of PAC over a treatment system using three sequential contact tanks, a combination of the benefits of powdered and granular carbon performance was achieved. The treatment system was designed so that recirculation could be introduced to any of the three tanks to investigate the effect of recirculation on the adsorption performance. This was compared to use of the setup, but without recirculation. A higher degree of pharmaceutical removal was achieved in all recirculation setups, both overall and with respect to specific substances, as compared to without recirculation. Recirculation was tested with nominal contact times of 30, 60 and 120 min and the goal of 95% removal could be achieved already at the shortest contact times at a PAC dose of 10-15 mg/L. In particular, the overall removal could be increased even to 97% and 99%, at 60 and 120 min, respectively, when the recirculation point was the first tank. Recirculation of PAC to either the first or the second contact tank proved to be comparable, while a slightly lower performance was observed with recirculation to the third tank. With regards to individual substances, clarithromycin and diclofenac were ubiquitously removed according to the set goal and in contrast, a few substances (fluconazole, irbesartan, memantine and venlafaxine) required specific settings to reach an acceptable removal. Copyright © 2017 Elsevier Ltd. All rights reserved.

The light ion pulsed power induction accelerator for ETF

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mazarakis, M.G.; Olson, R.E.; Olson, C.L.

1994-12-31

Our Engineering Test Facility (ETF) driver concept is based on HERMES III and RHEPP technologies. Actually, it is a scaled-down version of the LMF design incorporating repetition rate capabilities of up to 10 Hz CW. The preconceptual design presented here provides 200-TW peak power to the ETF target during 10 ns, equal to 2-MJ total ion beam energy. Linear inductive voltage addition driving a self-magnetically insulated transmission line (MITL) is utilized to generate the 36-MV peak voltage needed for lithium ion beams. The {approximately} 3-MA ion current is achieved by utilizing many accelerating modules in parallel. Since the current permore » module is relatively modest ({approximately}300 kA), two-stage or one-stage extraction diodes can be utilized for the generation of singly charged lithium ions. The accelerating modules are arranged symmetrically around the fusion chamber in order to provide uniform irradiation onto the ETF target. In addition, the modules are fired in a programmed sequence in order to generate the optimum power pulse shape onto the target. This design utilizes RHEPP accelerator modules as the principal power source.« less

The difference in LET and ion species dependence for induction of initially measured and non-rejoined chromatin breaks in normal human fibroblasts.

PubMed

Tsuruoka, Chizuru; Suzuki, Masao; Hande, M Prakash; Furusawa, Yoshiya; Anzai, Kazunori; Okayasu, Ryuichi

2008-08-01

We studied the LET and ion species dependence of the induction of chromatin breaks measured immediately after irradiation as initially measured breaks and after 24 h postirradiation incubation (37 degrees C) as non-rejoined breaks in normal human fibroblasts with different heavy ions, such as carbon, neon, silicon and iron, generated by the Heavy Ion Medical Accelerator in Chiba (HIMAC) at the National Institute of Radiological Science (NIRS). Chromatin breaks were measured as an excess number of fragments of prematurely condensed chromosomes using premature chromosome condensation (PCC). The results showed that the number of excess fragments per cell per Gy for initially measured chromatin breaks was dependent on LET in the range from 13.3 to 113.1 keV/mum but was not dependent on ion species. On the other hand, the number of non-rejoined chromatin breaks detected after 24 h postirradiation incubation was clearly dependent on both LET and ion species. No significant difference was observed in the cross section for initially measured breaks, but a statistically significant difference was observed in the cross section for non-rejoined breaks among carbon, neon, silicon and iron ions. This suggests that the LET-dependent structure in the biological effects is reflected in biological consequences of repair processes.

Induction of acute brain injury in mice by irradiation with high-LET charged particles

NASA Astrophysics Data System (ADS)

Liu, Yang; Zhang, Hong

The present study was performed to evaluate the induction of acute brain injury in mice after 235 Mev/u carbon ion irradiation. In our study, young outbred Kunming mice were divided into four treatment groups according to the penetration depth of carbon ions. Animals were irradiated with a sublethal dose of carbon ion beams prior to the Bragg curve. An experiment was performed to evaluate the acute alterations in histology, DNA double-strand breaks (DNA DSBs) as well as p53and Bax expression in the brain 96 h post-irradiation. The results demonstrated that various histopathological changes, a significant number of DNA DSBs and elevated p53 and Bax protein expression were induced in the brain following exposure to carbon ions. This was particularly true for mice irradiated with ions having a 9.1 cm-pentration depth, indicating that carbon ions can led to deleterious lesions in the brain of young animals within 96 h. Moreover, there was a remarkable increase in DNA DSBs and in the severity of histopathological changes as the penetration depths of ions increased, which may be associated with the complex track structure of heavy ions. These data reveal that carbon ions can promote serious neuropathological degeneration in the cerebral cortex of young mice. Given that damaged neurons cannot regenerate, these findings warrant further investigation of the adverse effects of the space radiation and the passage of a therapeutic heavy ion beam in the plateau region of the Bragg curve through healthy brain tissue.

Investigation of induced recirculation during planned ventilation system maintenance

PubMed Central

Pritchard, C.J.; Scott, D.F.; Noll, J.D.; Voss, B.; Leonis, D.

2015-01-01

The Office of Mine Safety and Health Research (OMSHR) investigated ways to increase mine airflow to underground metal/nonmetal (M/NM) mine working areas to improve miners’ health and safety. One of those areas is controlled recirculation. Because the quantity of mine air often cannot be increased, reusing part of the ventilating air can be an effective alternative, if implemented properly, until the capacity of the present system is improved. The additional airflow can be used to provide effective dilution of contaminants and higher flow velocities in the underground mine environment. Most applications of controlled recirculation involve taking a portion of the return air and passing it back into the intake to increase the air volume delivered to the desired work areas. OMSHR investigated a Nevada gold mine where shaft rehabilitation was in progress and one of the two main fans was shut down to allow reduced air velocity for safe shaft work. Underground booster fan operating pressures were kept constant to maintain airflow to work areas, inducing controlled recirculation in one work zone. Investigation into system behavior and the effects of recirculation on the working area during times of reduced primary ventilation system airflow would provide additional information on implementation of controlled recirculation into the system and how these events affect M/NM ventilation systems. The National Institute for Occupational Safety and Health monitored the ventilation district when both main fans were operating and another scenario with one of the units turned off for maintenance. Airflow and contaminants were measured to determine the exposure effects of induced recirculation on miner health. Surveys showed that 19% controlled recirculation created no change in the overall district airflow distribution and a small reduction in district fresh air intake. Total dust levels increased only modestly and respirable dust levels were also low. Diesel particulate matter (DPM) levels showed a high increase in district intake mass flow, but minor increases in exposure levels related to the recirculation percentage. Utilization of DPM mass flow rates allows input into ventilation modeling programs to better understand and plan for ventilation changes and district recirculation effects on miners’ health. PMID:26190862

Calcium ions and osteoclastogenesis initiate the induction of bone formation by coral-derived macroporous constructs

PubMed Central

Klar, Roland M; Duarte, Raquel; Dix-Peek, Therese; Dickens, Caroline; Ferretti, Carlo; Ripamonti, Ugo

2013-01-01

Coral-derived calcium carbonate/hydroxyapatite macroporous constructs of the genus Goniopora with limited hydrothermal conversion to hydroxyapatite (7% HA/CC) initiate the induction of bone formation. Which are the molecular signals that initiate pattern formation and the induction of bone formation? To evaluate the role of released calcium ions and osteoclastogenesis, 7% HA/CC was pre-loaded with either 500 μg of the calcium channel blocker, verapamil hydrochloride, or 240 μg of the osteoclast inhibitor, biphosphonate zoledronate, and implanted in the rectus abdominis muscle of six adult Chacma baboons Papio ursinus. Generated tissues on days 15, 60 and 90 were analysed by histomorphometry and qRT-PCR. On day 15, up-regulation of type IV collagen characterized all the implanted constructs correlating with vascular invasion. Zoledronate-treated specimens showed an important delay in tissue patterning and morphogenesis with limited bone formation. Osteoclastic inhibition yielded minimal, if any, bone formation by induction. 7% HA/CC pre-loaded with the Ca++ channel blocker verapamil hydrochloride strongly inhibited the induction of bone formation. Down-regulation of bone morphogenetic protein-2 (BMP-2) together with up-regulation of Noggin genes correlated with limited bone formation in 7% HA/CC pre-loaded with either verapamil or zoledronate, indicating that the induction of bone formation by coral-derived macroporous constructs is via the BMPs pathway. The spontaneous induction of bone formation is initiated by a local peak of Ca++ activating stem cell differentiation and the induction of bone formation. PMID:24106923

Modelling Of Chlorine Inductive Discharges

NASA Astrophysics Data System (ADS)

Chabert P.; Despiau-Pujo, E.

2010-07-01

III-V compounds such as GaAs, InP or GaN-based materials are increasingly important for their use in optoelectronic applications, especially in the telecommunications and light detection industries. Photonic devices including lasers, photodetectors or LEDs, require reliable etching processes characterized by high etch rate, profile control and low damage. Although many problems remain to be understood, inductively coupled discharges seem to be promising to etch such materials, using Cl2/Ar, Cl2/N2 and Cl2/H2 gas chemistries. Inductively coupled plasma (ICP) sources meet most of the requirements for efficient plasma processing such as high etch rates, high ion densities and low controllable ion energies. However, the presence of a negative ion population in the plasma alters the positive ion flux, reduces the electron density, changes the electron temperature, modifies the spatial structure of the discharge and can cause unstable operation. Several experimental studies and numerical simulation results have been published on inductively coupled Cl2/Ar plasmas but relatively few systematic comparisons of model predictions and experimental data have been reported in given reactor geometries under a wide range of op- erating conditions. Validation of numerical predictions is essential for chemically complex plasma processing and there is a need to benchmark the models with as many measurements as possible. In this paper, comparisons of 2D fluid simulations with experimental measurements of Ar/Cl2 plasmas in a low pressure ICP reactor are reported (Corr et al. 2008). The electron density, negative ion fraction and Cl atom density are investigated for various conditions of Ar/Cl2 ratio, gas pressure and applied RF power in H mode. Simulations show that the wall recombination coefficient of Cl atom (?) is a key parameter of the model and that neutral densities are very sensitive to its variations. The best agreement between model and experiment is obtained for ? = 0.02, which is much lower than the value predicted for stainless steel walls (? = 0.6). This is consistent with reactor wall contaminations classi- cally observed in such discharges. The plasma electronegativity decreases with RF power and increases with Cl2 content. At high pressure, the power absorption and distribution of charged particles become more localized below the quartz window. Although the experi- mental trends are well reproduced by the model, the calculated charged particle densities are systematically overestimated by a factor of 3-5. The reasons for this discrepancy are discussed in the paper. Experimental studies have also shown that low-pressure inductive discharges operating with electronegative gases are subject to instabilities near the transition between capacitive (E) and inductive (H) modes. A global model, consisting of two particle balance equations and one energy balance equation, has been previously proposed to describe the instability mechanism in SF6/ArSF6 (Lieberman et al. 1999). This model, which agrees qualitatively well with experimental observations, leaves significant quantitative differences. In this work, this global model is revisited with Cl2 as the feedstock gas (Despiau-Pujo and Chabert 2009). An alternative treatment of the inductive power deposition is evaluated and chlorine chemistry is included. Old and new models are systematically compared. The alternative inductive coupling description slightly modifies the results. The effect of gas chemistry is even more pronounced. The instability window is smaller in pressure and larger in absorbed power, the frequency is higher and the amplitudes of oscillations are reduced. The feedstock gas is weakly dissociated (~16%) and Cl2+ is the dominant positive ion, which is consistent with the moderate electron density during the instability cycle.

Effect of a solar Fered-Fenton system using a recirculation reactor on biologically treated landfill leachate.

PubMed

Ye, Zhihong; Zhang, Hui; Yang, Lin; Wu, Luxue; Qian, Yue; Geng, Jinyao; Chen, Mengmeng

2016-12-05

The effects of electrochemical oxidation (EO), Fered-Fenton and solar Fered-Fenton processes using a recirculation flow system containing an electrochemical cell and a solar photo-reactor on biochemically treated landfill leachate were investigated. The most successful method was solar Fered-Fenton which achieved 66.5% COD removal after 120min treatment utilizing the optimum operating conditions of 47mM H2O2, 0.29mM Fe(2+), pH0 of 3.0 and a current density of 60mA/cm(2). The generation of hydroxyl radicals (OH) are mainly from Fered-Fenton process, which is enhanced by the introduction of renewable solar energy. Moreover, Fe(2+)/chlorine and UV/chlorine processes taking place in this system also result in additional production of OH due to the relatively high concentration of chloride ions contained in the leachate. The energy consumption was 74.5kWh/kg COD and the current efficiency was 36.4% for 2h treatment. In addition, the molecular weight (MW) distribution analysis and PARAFAC analysis of excitation emission matrix (EEM) fluorescence spectroscopy for different leachate samples indicated that the organics in the leachate were significantly degraded into either small molecular weight species or inorganics. Copyright © 2016 Elsevier B.V. All rights reserved.

Industrialization of the ion plating process

NASA Technical Reports Server (NTRS)

Spalvins, T.

1976-01-01

A new process referred to as ion plating by induction heating (IPIH) is described, which combines the advantages of both ion plating and induction heating. The IPIH apparatus consists of the specimen (cathode) to be coated and the evaporation heating source, which is a ceramic crucible containing the metal to be heated. The specimen is an internal part of the high-voltage ceramic-metal vacuum feedthrough and is connected to the negative terminal of the high-voltage power supply, the positive terminal of the power supply being grounded. The plating conditions are the same as those most commonly used in industrial ion plating. A number of metals - such as nickel, iron, platinum - which were practically impossible to deposit by resistance heating evaporation can now be effectively evaporated and deposited to any desired thickness. Excellent adherence is observed for many metals deposited on various metal surfaces in thicknesses from 0.15 to 50 microns, regardless of the materials selected for coating and substrate.

77 FR 19740 - Water Sources for Long-Term Recirculation Cooling Following a Loss-of-Coolant Accident

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-02

... NUCLEAR REGULATORY COMMISSION [NRC-2010-0249] Water Sources for Long-Term Recirculation Cooling... Regulatory Guide (RG) 1.82, ``Water Sources for Long-Term Recirculation Cooling Following a Loss-of-Coolant... regarding the sumps and suppression pools that provide water sources for emergency core cooling, containment...

An evaluation of a micro programmable logic controller for oxygen monitoring and control in tanks of a recirculating aquaculture system

USDA-ARS?s Scientific Manuscript database

Control of dissolved gases, especially oxygen is an essential component of recirculating aquaculture systems. The use of pure oxygen in a recirculating aquaculture system creates supersaturated concentrations of dissolved oxygen and can reduce fish production costs by supporting greater fish and fee...

Sensitivity of bandpass filters using recirculating delay-line structures

NASA Astrophysics Data System (ADS)

Heyde, Eric C.

1996-12-01

Recirculating delay lines have value notably as sensors and optical signal processors. Most useful applications depend on a high-finesse response from a network. A proof that, with given response parameters, more complex systems can produce behavior that is more stable to the effects of nonidealities than a single recirculating loop is presented.

Residual chromatin breaks as biodosimetry for cell killing by carbon ions.

PubMed

Suzuki, M; Kase, Y; Nakano, T; Kanai, T; Ando, K

1998-01-01

We have studied the relationship between cell killing and the induction of residual chromatin breaks on various human cell lines and primary cultured cells obtained by biopsy from patients irradiated with either X-rays or heavy-ion beams to identify potential bio-marker of radiosensitivity for radiation-induced cell killing. The carbon-ion beams were accelerated with the Heavy Ion Medical Accelerator in Chiba (HIMAC). Six primary cultures obtained by biopsy from 6 patients with carcinoma of the cervix were irradiated with two different mono-LET beams (LET = 13 keV/micrometer, 76 keV/micrometer) and 200kV X rays. Residual chromatin breaks were measured by counting the number of non-rejoining chromatin fragments detected by the premature chromosome condensation (PCC) technique after a 24 hour post-irradiation incubation period. The induction rate of residual chromatin breaks per cell per Gy was the highest for 76 keV/micrometer beams on all of the cells. Our results indicated that cell which was more sensitive to the cell killing was similarly more susceptible to induction of residual chromatin breaks. Furthermore there is a good correlation between these two end points in various cell lines and primary cultured cells. This suggests that the detection of residual chromatin breaks by the PCC technique may be useful as a predictive assay of tumor response to cancer radiotherapy.

Residual chromatin breaks as biodosimetry for cell killing by carbon ions

NASA Astrophysics Data System (ADS)

Suzuki, M.; Kase, Y.; Nakano, T.; Kanai, T.; Ando, K.

1998-11-01

We have studied the relationship between cell killing and the induction of residual chromatin breaks on various human cell lines and primary cultured cells obtained by biopsy from patients irradiated with either X-rays or heavy-ion beams to identify potential bio-marker of radiosensitivity for radiation-induced cell killing. The carbon-ion beams were accelerated with the Heavy Ion Medical Accelerator in Chiba (HIMAC). Six primary cultures obtained by biopsy from 6 patients with carcinoma of the cervix were irradiated with two different mono-LET beams (LET = 13 keV/μm, 76 keV/μm) and 200kV X rays. Residual chromatin breaks were measured by counting the number of non-rejoining chromatin fragments detected by the premature chromosome condensation (PCC) technique after a 24 hour post-irradiation incubation period. The induction rate of residual chromatin breaks per cell per Gy was the highest for 76 keV/μm beams on all of the cells. Our results indicated that cell which was more sensitive to the cell killing was similarly more susceptible to induction of residual chromatin breaks. Furthermore there is a good correlation between these two end points in various cell lines and primary cultured cells. This suggests that the detection of residual chromatin breaks by the PCC technique may be useful as a predictive assay of tumor response to cancer radiotherapy.

Combustion-gas recirculation system

DOEpatents

Baldwin, Darryl Dean

2007-10-09

A combustion-gas recirculation system has a mixing chamber with a mixing-chamber inlet and a mixing-chamber outlet. The combustion-gas recirculation system may further include a duct connected to the mixing-chamber inlet. Additionally, the combustion-gas recirculation system may include an open inlet channel with a solid outer wall. The open inlet channel may extend into the mixing chamber such that an end of the open inlet channel is disposed between the mixing-chamber inlet and the mixing-chamber outlet. Furthermore, air within the open inlet channel may be at a pressure near or below atmospheric pressure.

Simultaneous carbon and nitrogen removal from anaerobic effluent of the cassava ethanol industry.

PubMed

Yin, Zhixuan; Xie, Li; Zhou, Qi; Bi, Xuejun

2018-03-01

This study investigated the simultaneous carbon and nitrogen removal from anaerobic effluent of cassava stillage using a lab-scale integrated system consisting of an upflow anaerobic sludge blanket (UASB) reactor and an activated sludge (AS) process. Simultaneous denitrification and methanogenesis (SDM) was observed in the UASB with nitrate recirculation. Compared with the blank reactor without recirculation, the overall chemical oxygen demand (COD) removal efficiencies in the combined system with nitrate recirculation were similar (80-90%), while the TN removal efficiencies were significantly improved from 4.7% to 71.0%. Additionally, the anaerobic COD removal efficiencies increased from 21% to 40% as the recirculation ratio decreased from 3 to 1. Although the influent nitrate concentrations fluctuated (60-140 mg N/L), the nitrate removal efficiencies could be maintained at about 97% under different recirculation conditions. With the decreasing recirculation ratio from 3 to 1, the CH 4 content in biogas improved from 2% to 40% while the N 2 content reduced from 95.8% to 50.6%. The 16S rDNA sequencing results indicated that bacteria diversity in anaerobic SDM granular sludge was much higher than archaea. The effect of recirculation ratios on the bacterial and archaeal communities in SDM granular sludge could be further confirmed by the relative abundance of denitrifying bacteria. Copyright © 2017 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

Radiation effects in space

NASA Astrophysics Data System (ADS)

Fry, R. J. M.

The radiation protection guidelines of the National Aeronautics and Space Administration (NASA) are under review by Scientific Committe 75 of the National Council on Radiation Protection and Measurements. The re-evaluation of the current guidelines is necessary, first, because of the increase in information about radiation risks since 1970 when the original recommendations were made and second, the population at risk has changed. For example, women have joined the ranks of the astronauts. Two types of radiation, protons and heavy ions, are of particular concern in space. Unfortunately, there is less information about the effects on tissues and the induction of cancer by these radiations than by other radiations. The choice of Quality Factors (Q) for obtaining dose equivalents for these radiations, is an important aspect of the risk estimate for space travel. There are not sufficient data for the induction of late effects by either protons or by heavy ions. The current information suggests a RBE for the relative protons of about 1, whereas, -a RBE of 20 for tumor induction by heavy ions, such as iron-56, appears appropriate. The recommendations for the dose equivalent career limits for skin and the lens of the eye have been reduced but the 30-day and annual limits have been raised.

Calculation of the non-inductive current profile in high-performance NSTX plasmas

NASA Astrophysics Data System (ADS)

Gerhardt, S. P.; Fredrickson, E.; Gates, D.; Kaye, S.; Menard, J.; Bell, M. G.; Bell, R. E.; Le Blanc, B. P.; Kugel, H.; Sabbagh, S. A.; Yuh, H.

2011-03-01

The constituents of the current profile have been computed for a wide range of high-performance plasmas in NSTX (Ono et al 2000 Nucl. Fusion 40 557); these include cases designed to maximize the non-inductive fraction, pulse length, toroidal-β or stored energy. In the absence of low-frequency MHD activity, good agreement is found between the reconstructed current profile and that predicted by summing the independently calculated inductive, pressure-driven and neutral beam currents, without the need to invoke any anomalous beam ion diffusion. Exceptions occur, for instance, when there are toroidal Alfvén eigenmode avalanches or coupled m/n = 1/1 + 2/1 kink-tearing modes. In these cases, the addition of a spatially and temporally dependent fast-ion diffusivity can reduce the core beam current drive, restoring agreement between the reconstructed profile and the summed constituents, as well as bringing better agreement between the simulated and measured neutron emission rate. An upper bound on the fast-ion diffusivity of ~0.5-1 m2 s-1 is found in 'MHD-free' discharges, based on the neutron emission, the time rate of change in the neutron signal when a neutral beam is stepped and reconstructed on-axis current density.

Use of a micro programmable logic controller for oxygen monitoring and control in multiple tanks of a recirculating aquaculture system

USDA-ARS?s Scientific Manuscript database

In intensive recirculating aquaculture systems the use of supplemental oxygen, specifically pure liquid oxygen, increases the mass of fish that can be supported and eliminates oxygen as a major limiting factor to a system’s carrying capacity. The use of pure oxygen in a recirculating aquaculture sys...

Apparatus for controlling air/fuel ratio for internal combustion engine

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kato, K.; Mizuno, T.

1986-07-08

This patent describes an apparatus for controlling air-fuel ratio of an air-fuel mixture to be supplied to an internal combustion engine having an intake passage, an exhaust passage, an an exhaust gas recirculation passage for recirculating exhaust gases in the exhaust passage to the intake passage therethrough. The apparatus consists of: (a) means for sensing rotational speed of the engine; (b) means for sensing intake pressure in the intake passage; (c) means for sensing atmospheric pressure; (d) means for enabling and disabling exhaust gas recirculation through the exhaust gas recirculation passage in accordance with operating condition of the engine; (e)more » means for determining required amount of fuel in accordance with the sensed rotational speed and the sensed intake pressure; (f) means for determining, when the exhaust gas recirculation is enabled, a first correction value in accordance with the sensed rotational speed, the sensed intake pressure and the sensed atmospheric pressure, the first correction factor being used for correcting fuel amount so as to compensate for the decrease of fuel due to the performance of exhaust gas recirculation and also to compensate for the change in atmospheric pressure; (g) means for determining, when the exhaust gas recirculation is disabled, a second correction value in accordance with the atmospheric pressure, the second correction factor being used so as to compensate for the change in atmospheric pressure; (h) means for correcting the required amount of fuel by the first correction value and the second correction value when the exhaust gas recirculation is enabled and disabled respectively; and (i) means for supplying the engine with the corrected amount of fuel.« less

Experimental investigation of aerodynamics, combustion, and emissions characteristics within the primary zone of a gas turbine combustor

NASA Astrophysics Data System (ADS)

Elkady, Ahmed M.

2006-04-01

The present work investigates pollutant emissions production, mainly nitric oxides and carbon monoxide, within the primary zone of a highly swirling combustion and methods with which to reduce their formation. A baseline study was executed at different equivalence ratios and different inlet air temperatures. The study was then extended to investigate the effects of utilizing transverse air jets on pollutant emission characteristics at different jet locations, jet mass ratio, and overall equivalence ratio as well as to investigate the jets' overall interactions with the recirculation zone. A Fourier Transform Infrared (FTIR) spectrometer was employed to measure emissions concentrations generated during combustion of Jet-A fuel in a swirl-cup assembly. Laser Doppler Velocimetry (LDV) was employed to investigate the mean flow aerodynamics within the combustor. Particle Image Velocimetry (PIV) was utilized to capture the instantaneous aerodynamic behavior of the non-reacting primary zone. Results illustrate that NOx production is a function of both the recirculation zone and the flame length. At low overall equivalence ratios, the recirculation zone is found to be the main producer of NOx. At near stoichiometric conditions, the post recirculation zone appears to be responsible for the majority of NOx produced. Results reveal the possibility of injecting air into the recirculation zone without altering flame stability to improve emission characteristics. Depending on the jet location and strength, nitric oxides as well as carbon monoxide can be reduced simultaneously. Placing the primary air jet just downstream of the fuel rich recirculation zone can lead to a significant reduction in both nitric oxides and carbon monoxide. In the case of fuel lean recirculation zone, reduction of nitric oxides can occur by placing the jets below the location of maximum radius of the recirculation zone.

Case study of controlled recirculation at a Wyoming trona mine

PubMed Central

Pritchard, C.; Scott, D.; Frey, G.

2015-01-01

Controlled recirculation has been used in the metal/nonmetal mining industry for energy savings when heating and cooling air, in undersea mining and for increasing airflow to mining areas. For safe and effective use of controlled district recirculation, adequate airflow to dilute contaminants must exist prior to implementation, ventilation circuit parameters must be accurately quantified, ventilation network modeling must be up to date, emergency planning scenarios must be performed and effective monitoring and control systems must be installed and used. Safety and health issues that must be considered and may be improved through the use of controlled district recirculation include blasting fumes, dust, diesel emissions, radon and contaminants from mine fires. Controlled recirculation methods are expected to become more widely used as mines reach greater working depths, requiring that these health and safety issues be well understood. The U.S. National Institute for Occupational Safety and Health (NIOSH) conducted two controlled recirculation tests over three days at a Wyoming trona mine, utilizing an inline booster fan to improve airflow to a remote and difficult-to-ventilate development section. Test results were used to determine the effect that recirculation had on air qualities and quantities measured in that section and in other adjacent areas. Pre-test conditions, including ventilation quantities and pressures, were modeled using VnetPC. During each test, ventilation quantities and pressures were measured, as well as levels of total dust. Sulfur hexafluoride (SF6) tracer gas was used to simulate a mine contaminant to monitor recirculation wave cycles. Results showed good correlation between the model results and measured values for airflows, pressure differentials, tracer gas arrival times, mine gasses and dust levels. PMID:26251567

Characterisation of recirculation zones in complex terrain using multi-lidar measurements

NASA Astrophysics Data System (ADS)

Menke, R.; Mann, J.; Vasiljevic, N.

2017-12-01

Wind fields in complex terrain show a higher complexity compared to sites with simpler geometries. It is imperative to understand well the characteristics of complex flows to account for them during the site validation to ensure the wind turbines can withstand the local flow conditions. This study focuses on the description of recirculation zones occurring on lee sides of hills. The flow recirculation can have a significant impact on the success of wind energy projects since it represents one of the main contributors to the turbulence generation. An extensive dataset of observation of flow over complex terrain is available from the Perdigão 2017 field campaign (https://www.nature.com/news/world-s-largest-wind-mapping-project-spins-up-in-portugal-1.21481). A setup of 8 long-range WindScanners (Vasiljević et al., 2016), scanning lidars deployed by DTU performed RHI scans at several positions along two parallel ridges probing the flow field in two vertical planes, in addition data from several meteorological masts is available. With the above-mentioned lidar setup we achieved simultaneous dual-Doppler scans of the recirculation zone at three positions and simultaneous observations of recirculation behind two parallel ridges. Methods are developed to identify and define the extent of recirculation bubbles. Different parameters are defined to characterise the dimensions of the recirculation zone. The change of these parameters along the ridges is studied. In particular, the impact of atmospheric stability and the changes of the wind field at the position of the downwind ridge are investigated. Furthermore, the geometry of the recirculation zone for different wind directions and in connection to the upstream wind conditions is investigated.

Altering rainfall patterns through aerosol dispersion

NASA Astrophysics Data System (ADS)

Emetere, M. E.; Bakeko, M.; Onyechekwa, L.; Ayara, W.

2017-05-01

The possibility of recirculation mechanism on rainfall patterns is salient for sustenance of the human race through agricultural produce. The peculiarity of the lower atmosphere of south west region of Nigeria was explored using theoretical and experimental approach. In the theoretical approach, the reconstruction of 1D model as an extraction from the 3D aerosol dispersion model was used to examine the physics of the recirculation theory. The experimental approach which consists of obtaining dataset from ground instruments was used to provide on-site guide for developing the new recirculation theories. The data set was obtained from the Davis weather station, Nigeria Meteorological agency and Multi-angle Imaging Spectro-radiometer (MISR). We looked at the main drivers of recirculation and propounded that recirculation is a complex process which triggers a reordering of the mixing layer- a key factor for initiating the type of rainfall in this region.

STORAGE RING CROSS SECTION MEASUREMENTS FOR ELECTRON IMPACT SINGLE AND DOUBLE IONIZATION OF Fe{sup 13+} AND SINGLE IONIZATION OF Fe{sup 16+} AND Fe{sup 17+}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hahn, M.; Novotny, O.; Savin, D. W.

2013-04-10

We report measurements of electron impact ionization for Fe{sup 13+}, Fe{sup 16+}, and Fe{sup 17+} over collision energies from below threshold to above 3000 eV. The ions were recirculated using an ion storage ring. Data were collected after a sufficiently long time that essentially all the ions had relaxed radiatively to their ground state. For single ionization of Fe{sup 13+}, we find that previous single pass experiments are more than 40% larger than our results. Compared to our work, the theoretical cross section recommended by Arnaud and Raymond is more than 30% larger, while that of Dere is about 20%more » greater. Much of the discrepancy with Dere is due to the theory overestimating the contribution of excitation-autoionization via n = 2 excitations. Double ionization of Fe{sup 13+} is dominated by direct ionization of an inner shell electron accompanied by autoionization of a second electron. Our results for single ionization of Fe{sup 16+} and Fe{sup 17+} agree with theoretical calculations to within the experimental uncertainties.« less

Apparatus for photocatalytic treatment of liquids

NASA Technical Reports Server (NTRS)

Cooper, Gerald (Inventor); Ratcliff, Matthew A. (Inventor)

1992-01-01

Apparatus for decontaminating a contaminated fluid by using photocatalytic particles. The apparatus includes a reactor tank for holding a slurry of the contaminated fluid and the photocatalytic particles ultraviolet light irradiates the surface of the slurry, thereby activating the photocatalytic properties of the particles. Stirring blades for continuously agitate the irradiated fluid surface maintaining the particles in a suspended state within the fluid. A cross flow filter is used for separating the fluid from the semiconductor powder after the decomposition reaction is ended. The cross flow filter is occasionally back flushed to remove any caked semiconductor powder. The semiconductor powder may be recirculated back to the tank for reuse, or may be stored for future use. A series of reactor tanks may be used to gradually decompose a chemical in the fluid. The fluid may be pretreated to remove certain metal ions which interfere with the photocatalytic process. Such pretreatment may be accomplished by dispersing semiconductor particles within the fluid, which particles adsorb ions or photodeposit the metal as the free metal or its insoluble oxide or hydroxide, and then removing the semiconductor particles together with the adsorbed metal ions/oxides/hydroxide/free metal from the fluid.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hwang, Kilean; Qiang, Ji

A recirculating superconducting linear accelerator with the advantage of both straight and circular accelerator has been demonstrated with relativistic electron beams. The acceleration concept of a recirculating proton beam was recently proposed and is currently under study. In order to further support the concept, the beam dynamics study on a recirculating proton linear accelerator has to be carried out. In this paper, we study the feasibility of a two-pass recirculating proton linear accelerator through the direct numerical beam dynamics design optimization and the start-to-end simulation. This study shows that the two-pass simultaneous focusing without particle losses is attainable including fullymore » 3D space-charge effects through the entire accelerator system.« less

Validation of enhanced stabilization of municipal solid waste under controlled leachate recirculation using FTIR and XRD.

PubMed

Sethi, Sapna; Kothiyal, N C; Nema, Arvind K

2012-07-01

Leachate recirculation at neutral PH accompanied with buffer/nutrients addition has been used successfully in earlier stabilization of municipal solid waste in bioreactor landfills. In the present study, efforts were made to enhance the stabilization rate of municipal solid waste (MSW) and organic solid waste (OSW) in simulated landfill bioreactors by controlling the pH of recirculated leachate towards slightly alkaline side in absence of additional buffer and nutrients addition. Enhanced stabilization in waste samples was monitored with the help of analytical tools like Fourier Transform Infrared Spectroscopy (FTIR) and X-Ray Diffraction (XRD). Predominance of bands assigned to inorganic compounds and comparatively lower intensities of bands for organic compounds in the FTIR spectra of waste samples degraded with leachate recirculation under controlled pH confirmed higher rate of biodegradation and mineralization of waste than the samples degraded without controlled leachate recirculation. XRD spectra also confirmed to a greater extent of mineralization in the waste samples degraded under leachate recirculation with controlled pH. Comparison of XRD spectra of two types of wastes pointed out higher degree of mineralization in organic solid waste as compared to municipal solid waste.

Investigation of High-Intensity Ion Beam Generation in the Diode with External Magnetic Insulation and Explosive Plasma Emission Source

NASA Astrophysics Data System (ADS)

Shamanin, V. I.; Stepanov, A. V.; Rysbaev, K. Zh.

2018-04-01

The ion Br-diode in which plasma is generated under the action of a negative pre-pulse voltage is presented. Preliminary plasma formation allows the energy released in the diode during a positive voltage pulse to be increased. The high-energy ion beam parameters are investigated for the magnetic field induction changing from 0.8Bcr to 1.7Bcr.

ARIEL e-LINAC: Commissioning and Development

NASA Astrophysics Data System (ADS)

Laxdal, R. E.; Zvyagintsev, V.

2016-09-01

A superconducting electron Linac (e-Linac) will be a part of the ARIEL facility for the production of radioactive ion beams (RIB) at TRIUMF. The e-Linac will consist of five 1.3GHz 9-cell cavities in three cryomodules delivering a 50MeV 10mA beam. The baseline operation will be single pass but a re-circulating ring is planned to allow either energy boost or energy recovery operation. The first stage of the accelerator which consists of two cryomodules has been successfully commissioned in 2014. The paper will discuss the superconducting radio-frequency (SRF) challenges of the accelerator. Cavities, crymodules and RF system design, preparation, and performance will be presented.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leitner, M.; Bieniosek, F.; Kwan, J.

The Heavy Ion Fusion Science Virtual National Laboratory (HIFS-VNL), a collaboration between Lawrence Berkeley National Laboratory (LBNL), Lawrence Livermore National Laboratory (LLNL), and Princeton Plasma Physics Laboratory (PPPL), is currently constructing a new induction linear accelerator, called Neutralized Drift Compression eXperiment NDCX-II. The accelerator design makes effective use of existing components from LLNL's decommissioned Advanced Test Accelerator (ATA), especially induction cells and Blumlein voltage sources that have been transferred to LBNL. We have developed an aggressive acceleration 'schedule' that compresses the emitted ion pulse from 500 ns to 1 ns in just 15 meters. In the nominal design concept, 30more » nC of Li{sup +} are accelerated to 3.5 MeV and allowed to drift-compress to a peak current of about 30 A. That beam will be utilized for warm dense matter experiments investigating the interaction of ion beams with matter at high temperature and pressure. Construction of the accelerator will be complete within a period of approximately two and a half years and will provide a worldwide unique opportunity for ion-driven warm dense matter experiments as well as research related to novel beam manipulations for heavy ion fusion drivers.« less

Can we estimate plasma density in ICP driver through electrical parameters in RF circuit?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bandyopadhyay, M., E-mail: mainak@iter-india.org; Sudhir, Dass, E-mail: dass.sudhir@iter-india.org; Chakraborty, A., E-mail: arunkc@iter-india.org

2015-04-08

To avoid regular maintenance, invasive plasma diagnostics with probes are not included in the inductively coupled plasma (ICP) based ITER Neutral Beam (NB) source design. Even non-invasive probes like optical emission spectroscopic diagnostics are also not included in the present ITER NB design due to overall system design and interface issues. As a result, negative ion beam current through the extraction system in the ITER NB negative ion source is the only measurement which indicates plasma condition inside the ion source. However, beam current not only depends on the plasma condition near the extraction region but also on the perveancemore » condition of the ion extractor system and negative ion stripping. Nevertheless, inductively coupled plasma production region (RF driver region) is placed at distance (∼ 30cm) from the extraction region. Due to that, some uncertainties are expected to be involved if one tries to link beam current with plasma properties inside the RF driver. Plasma characterization in source RF driver region is utmost necessary to maintain the optimum condition for source operation. In this paper, a method of plasma density estimation is described, based on density dependent plasma load calculation.« less

SABRE, a 10-MV linear induction accelerator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Corely, J.P.; Alexander, J.A.; Pankuch, P.J.

SABRE (Sandia Accelerator and Beam Research Experiment) is a 10-MV, 250-kA, 40-ns linear induction accelerator. It was designed to be used in positive polarity output. Positive polarity accelerators are important for application to Sandia's ICF (Inertial Confinement Fusion) and LMF (Laboratory Microfusion Facility) program efforts. SABRE was built to allow a more detailed study of pulsed power issues associated with positive polarity output machines. MITL (Magnetically Insulated Transmission Line) voltage adder efficiency, extraction ion diode development, and ion beam transport and focusing. The SABRE design allows the system to operate in either positive polarity output for ion extraction applications ormore » negative polarity output for more conventional electron beam loads. Details of the design of SABRE and the results of initial machine performance in negative polarity operation are presented in this paper. 13 refs., 12 figs., 1 tab.« less

Removal of cationic pollutants from water by xanthated corn cob: optimization, kinetics, thermodynamics, and prediction of purification process.

PubMed

Kostić, Miloš; Đorđević, Miloš; Mitrović, Jelena; Velinov, Nena; Bojić, Danijela; Antonijević, Milan; Bojić, Aleksandar

2017-07-01

The removal of Cr(III) ions and methylene blue (MB) from aqueous solutions by xanthated corn cob (xCC) in batch conditions was investigated. The sorption capacity of xCC strongly depended of the pH, and increase when the pH rises. The kinetics was well fitted by pseudo-second-order and Chrastil's model. Sorption of Cr(III) ions and MB on xCC was rapid during the first 20 min of contact time and, thereafter, the biosorption rate decrease gradually until reaching equilibrium. The maximum sorption capacity of 17.13 and 83.89 mg g -1 for Cr(III) ions and MB, respectively, was obtained at 40 °C, pH 5, and sorbent dose 4 g dm -3 for removal of Cr(III) ions and 1 g dm -3 for removal of MB. The prediction of purification process was successfully carried out, and the verification of theoretically calculated amounts of sorbent was confirmed by using packed-bed column laboratory system with recirculation of the aqueous phase. The wastewater from chrome plating industry was successfully purified, i.e., after 40 min concentration of Cr(III) ions was decreased lower than 0.1 mg dm -3 . Also, removal of MB from the river water was successfully carried out and after 40 min, removal efficiency was about 94%.

Experimental Investigation of Combustion Stabilization in Supersonic Flow Using Free Recirculation Zones

DTIC Science & Technology

1997-08-01

NUMBERS Experimental Investigation of Combustion Stabilization in Supersonic Flow Using Free F6170896W0291 Recirculation Zones 6. AUTHOR(S) Dr...stabilization in supersonic flow using free recirculation zones Special contract (SPC-96-4043) with Air Force Office of Scientific Research (AFMC), USA, EOARD...of three quarterly reports and presents experimental results on self-ignition and combustion stabilization in supersonic flow using free

Monitoring extent of moisture variations due to leachate recirculation in an ELR/bioreactor landfill using resistivity imaging.

PubMed

Manzur, Shahed Rezwan; Hossain, Md Sahadat; Kemler, Vance; Khan, Mohammad Sadik

2016-09-01

Bioreactor or enhanced leachate recirculation (ELR) landfills are designed and operated for accelerated waste stabilization, accelerated decomposition, and an increased rate of gas generation. The major aspects of a bioreactor landfill are the addition of liquid and the recirculation of collected leachate back into the waste mass through the subsurface leachate recirculation system (LRS). The performance of the ELR landfill largely depends on the existing moisture content within the waste mass; therefore, it is of utmost importance to determine the moisture variations within the landfill. Traditionally, the moisture variation of the ELR landfill is determined by collecting samples through a bucket auger boring from the landfill, followed by laboratory investigation. Collecting the samples through a bucket auger boring is time consuming, labor intensive, and cost prohibitive. Moreover, it provides the information for a single point within the waste mass, but not for the moisture distribution within the landfill. Fortunately, 2D resistivity imaging (RI) can be performed to assess the moisture variations within the landfill and provide a continuous image of the subsurface, which can be utilized to evaluate the performance of the ELR landfill. During this study, the 2D resistivity imaging technique was utilized to determine the moisture distribution and moisture movement during the recirculation process of an ELR landfill in Denton, Texas, USA. A horizontal recirculation pipe was selected and monitored periodically for 2.5years, using the RI technique, to investigate the performance of the leachate recirculation. The RI profile indicated that the resistivity of the solid waste decreased as much as 80% with the addition of water/leachate through the recirculation pipe. In addition, the recirculated leachate traveled laterally between 11m and 16m. Based on the resistivity results, it was also observed that the leachate flow throughout the pipe was non-uniform. The non-uniformity of the leachate flow confirms that the flow of leachate through waste is primarily through preferential flow paths due the heterogeneous nature of the waste. Copyright © 2016 Elsevier Ltd. All rights reserved.

Effects of heavy ion radiation on the brain vascular system and embryonic development

NASA Technical Reports Server (NTRS)

Yang, T. C.; Tobias, C. A.

1984-01-01

The present investigation is concerned with the effects of heavy-ion radiation on the vascular system and the embryonic development, taking into account the results of experiments with neonatal rats and mouse embryos. It is found that heavy ions can be highly effective in producing brain hemorrhages and in causing body deformities. Attention is given to aspects of methodology, the induction of brain hemorrhages by X-rays and heavy ions, and the effect of iron particles on embryonic development. Reported results suggest that high linear energy transfer (LET) heavy ions can be very effective in producing developmental abnormalities.

Analysis of iodinated X-ray contrast agents in water samples by ion chromatography and inductively-coupled plasma mass spectrometry.

PubMed

Sacher, Frank; Raue, Brigitte; Brauch, Heinz-Jürgen

2005-08-26

In this paper, an analytical method for the determination of six iodinated X-ray contrast agents (amidotrizoic acid, iohexol, iomeprol, iopamidol, iopromide, and ioxitalamic acid), iodide, and iodate in water samples is presented. The method is based on a separation of the analytes by ion chromatography (IC) and a subsequent detection by inductively-coupled plasma mass spectrometry (ICP-MS). The method was optimised with respect to separation conditions (column type and eluent composition) and extensively validated. Without pre-concentration of the samples, limits of detection below 0.2 microg/l could be achieved whereby reproducibility was below 6% for all compounds under investigation.

Development of vertical compact ion implanter for gemstones applications

NASA Astrophysics Data System (ADS)

Intarasiri, S.; Wijaikhum, A.; Bootkul, D.; Suwannakachorn, D.; Tippawan, U.; Yu, L. D.; Singkarat, S.

2014-08-01

Ion implantation technique was applied as an effective non-toxic treatment of the local Thai natural corundum including sapphires and rubies for the enhancement of essential qualities of the gemstones. Energetic oxygen and nitrogen ions in keV range of various fluences were implanted into the precious stones. It has been thoroughly proved that ion implantation can definitely modify the gems to desirable colors together with changing their color distribution, transparency and luster properties. These modifications lead to the improvement in quality of the natural corundum and thus its market value. Possible mechanisms of these modifications have been proposed. The main causes could be the changes in oxidation states of impurities of transition metals, induction of charge transfer from one metal cation to another and the production of color centers. For these purposes, an ion implanter of the kind that is traditionally used in semiconductor wafer fabrication had already been successfully applied for the ion beam bombardment of natural corundum. However, it is not practical for implanting the irregular shape and size of gem samples, and too costly to be economically accepted by the gem and jewelry industry. Accordingly, a specialized ion implanter has been requested by the gem traders. We have succeeded in developing a prototype high-current vertical compact ion implanter only 1.36 m long, from ion source to irradiation chamber, for these purposes. It has been proved to be very effective for corundum, for example, color improvement of blue sapphire, induction of violet sapphire from low value pink sapphire, and amelioration of lead-glass-filled rubies. Details of the implanter and recent implantation results are presented.

Boosting devices with integral features for recirculating exhaust gas

DOEpatents

Wu, Ko-Jen

2015-12-22

According to one embodiment of the invention, a turbine housing includes a turbine inlet in fluid communication with a turbine volute configured to house a turbine wheel, the turbine inlet configured to direct an exhaust gas flow from an engine to the turbine wheel. The turbine housing also includes a turbine outlet in fluid communication with the turbine volute, the turbine outlet configured to direct the exhaust gas flow to an exhaust gas conduit and a first exhaust gas recirculation supply port located on and in fluid communication with the turbine outlet, the first exhaust gas recirculation supply port being configured to direct a portion of the exhaust gas flow to an exhaust gas recirculation supply conduit.

Prediction of recirculation zones in isothermal coaxial jet flows relevant to combustors

NASA Technical Reports Server (NTRS)

Nallasamy, M.

1987-01-01

The characteristics of the recirculation zones in confined coaxial turbulent jets are investigated numerically employing the kappa - epsilon turbulence model. The geometrical arrangement corresponds to the experimental study of Owen (AIAA J. 1976) and the investigation is undertaken to provide information for isothermal flow relevant to combustor flows. For the first time, the shape, size, and location of the recirculation zones for the above experimental configuration are correctly predicted. The processes leading to the observed results are explained. Detailed comparisons of the prediction with measurements are made. It is shown that the recirculation zones are very sensitive to the central jet exit configuration and the velocity ratio of the jets.

Magnetic Reconnection Processes Involving Modes Propagating in the Ion Diamagnetic Velocity Direction

NASA Astrophysics Data System (ADS)

Buratti, P.; Coppi, B.; Pucella, G.; Zhou, T.

2013-10-01

Experiments in weakly collisional plasma regimes, (e.g. neutral beam heated plasmas in the H-regime), measuring the Doppler shift associated with the plasma local rotation, have shown that the toroidal mode phase velocity vph in the frame with Er = 0 is in the direction of the ion diamagnetic velocity. For ohmically heated plasmas, with higher collisionalities, vph in the laboratory frame is in the direction of the electron diamagnetic velocity, but plasma rotation is reversed as well, and vph, in the Er = 0 frame, is in the ion diamagnetic velocity direction. Theoretically, two classes of reconnecting modes should emerge: drift-tearing modes and ``inductive modes'' that depend on the effects of a finite plasma inductivity. The former modes, with vph in the direction of the electron diamagnetic velocity, require the pre-excitation of a different kind of mode in order to become unstable in weakly collisional regimes. The second kind of modes has a growth rate associated with the relevant finite ion viscosity. A comprehensive theory is presented. Sponsored in part by the US DOE.

Multi-point optimization of recirculation flow type casing treatment in centrifugal compressors

NASA Astrophysics Data System (ADS)

Tun, Min Thaw; Sakaguchi, Daisaku

2016-06-01

High-pressure ratio and wide operating range are highly required for a turbocharger in diesel engines. A recirculation flow type casing treatment is effective for flow range enhancement of centrifugal compressors. Two ring grooves on a suction pipe and a shroud casing wall are connected by means of an annular passage and stable recirculation flow is formed at small flow rates from the downstream groove toward the upstream groove through the annular bypass. The shape of baseline recirculation flow type casing is modified and optimized by using a multi-point optimization code with a metamodel assisted evolutionary algorithm embedding a commercial CFD code CFX from ANSYS. The numerical optimization results give the optimized design of casing with improving adiabatic efficiency in wide operating flow rate range. Sensitivity analysis of design parameters as a function of efficiency has been performed. It is found that the optimized casing design provides optimized recirculation flow rate, in which an increment of entropy rise is minimized at grooves and passages of the rotating impeller.

Recirculating linacs for a neutrino factory - Arc optics design and optimization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alex Bogacz; Valeri Lebedev

2001-10-21

A conceptual lattice design for a muon accelerator based on recirculating linacs (Nucl. Instr. and Meth. A 472 (2001) 499, these proceedings) is presented here. The challenge of accelerating and transporting a large phase space of short-lived muons is answered here by presenting a proof-of-principle lattice design for a recirculating linac accelerator. It is the centerpiece of a chain of accelerators consisting of a 3GeV linac and two consecutive recirculating linear accelerators, which facilitates acceleration starting after ionization cooling at 190MeV/c and proceeding to 50GeV. Beam transport issues for large-momentum-spread beams are accommodated by appropriate lattice design choices. The resultingmore » arc optics is further optimized with a sextupole correction to suppress chromatic effects contributing to the emittance dilution. The presented proof-of-principle design of the arc optics with horizontal separation of multi-pass beams can be extended to all passes in both recirculating linacs.« less

Recirculating linacs for a neutrino factory - Arc optics design and optimization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Valeri Lebedev; S. Bogacz

2001-10-25

A conceptual lattice design for a muon accelerator based on recirculating linacs (Nucl. Instr. and Meth. A 472 (2001) 499, these proceedings) is presented here. The challenge of accelerating and transporting a large phase space of short-lived muons is answered here by presenting a proof-of-principle lattice design for a recirculating linac accelerator. It is the centerpiece of a chain of accelerators consisting of a 3 GeV linac and two consecutive recirculating linear accelerators, which facilitates acceleration starting after ionization cooling at 190 MeV/c and proceeding to 50 GeV. Beam transport issues for large-momentum-spread beams are accommodated by appropriate lattice designmore » choices. The resulting arc optics is further optimized with a sextupole correction to suppress chromatic effects contributing to the emittance dilution. The presented proof-of-principle design of the arc optics with horizontal separation of multi-pass beams can be extended to all passes in both recirculating linacs.« less

Confined turbulent swirling recirculating flow predictions. Ph.D. Thesis. Final Report

NASA Technical Reports Server (NTRS)

Abujelala, M. T.; Lilley, D. G.

1985-01-01

The capability and the accuracy of the STARPIC computer code in predicting confined turbulent swirling recirculating flows is presented. Inlet flow boundary conditions were demonstrated to be extremely important in simulating a flowfield via numerical calculations. The degree of swirl strength and expansion ratio have strong effects on the characteristics of swirling flow. In a nonswirling flow, a large corner recirculation zone exists in the flowfield with an expansion ratio greater than one. However, as the degree of inlet swirl increases, the size of this zone decreases and a central recirculation zone appears near the inlet. Generally, the size of the central zone increased with swirl strength and expansion ratio. Neither the standard k-epsilon turbulence mode nor its previous extensions show effective capability for predicting confined turbulent swirling recirculating flows. However, either reduced optimum values of three parameters in the mode or the empirical C sub mu formulation obtained via careful analysis of available turbulence measurements, can provide more acceptable accuracy in the prediction of these swirling flows.

Three-dimensional modelling of leachate recirculation using vertical wells in bioreactor landfills.

PubMed

Feng, Shi-Jin; Chen, Zheng-Wei; Cao, Ben-Yi

2016-12-01

Bioreactor landfills use leachate recirculation to enhance the biodegradation of municipal solid waste and accelerate landfill stabilisation, which can provide significant environmental and economic benefits. Vertical wells are operated as a major method for leachate recirculation systems. The objectives of this article are to analyse the leachate migration in bioreactor landfills using vertical wells and to offer theoretical basis for the design of leachate recirculation systems. A three-dimensional numerical model was built using FLAC-3D, and this model can consider the saturated and unsaturated flow of leachate within anisotropic waste to reflect the actual conditions. First, main influence factors of leachate migration were analysed, including the vertical well height, hydraulic conductivity, and anisotropic coefficient, in a single-well recirculation system. Then, the effects of different configurations of a group-well system were studied and the optimal well spacing was obtained. Some key design parameters (e.g. the recirculation flow rate, volume of impact zone, radius of impact zone and time to reach steady state) were also evaluated. The results show that the hydraulic conductivity has a great impact on the optimal height of vertical wells and uniform configuration is the best option in terms of both volume of impact zone and time to reach steady state. © The Author(s) 2016.

The impact of recirculation, ventilation and filters on secondary organic aerosols generated by indoor chemistry

NASA Astrophysics Data System (ADS)

Fadeyi, M. O.; Weschler, C. J.; Tham, K. W.

This study examined the impact of recirculation rates (7 and 14 h -1), ventilation rates (1 and 2 h -1), and filtration on secondary organic aerosols (SOAs) generated by ozone of outdoor origin reacting with limonene of indoor origin. Experiments were conducted within a recirculating air handling system that serviced an unoccupied, 236 m 3 environmental chamber configured to simulate an office; either no filter, a new filter or a used filter was located downstream of where outdoor air mixed with return air. For otherwise comparable conditions, the SOA number and mass concentrations at a recirculation rate of 14 h -1 were significantly smaller than at a recirculation rate of 7 h -1. This was due primarily to lower ozone concentrations, resulting from increased surface removal, at the higher recirculation rate. Increased ventilation increased outdoor-to-indoor transport of ozone, but this was more than offset by the increased dilution of SOA derived from ozone-initiated chemistry. The presence of a particle filter (new or used) strikingly lowered SOA number and mass concentrations compared with conditions when no filter was present. Even though the particle filter in this study had only 35% single-pass removal efficiency for 100 nm particles, filtration efficiency was greatly amplified by recirculation. SOA particle levels were reduced to an even greater extent when an activated carbon filter was in the system, due to ozone removal by the carbon filter. These findings improve our understanding of the influence of commonly employed energy saving procedures on occupant exposures to ozone and ozone-derived SOA.

Effect of recirculation on organic matter removal in a hybrid constructed wetland system.

PubMed

Ayaz, S C; Findik, N; Akça, L; Erdoğan, N; Kinaci, C

2011-01-01

This research project aimed to determine the technologically feasible and applicable wastewater treatment systems which will be constructed to solve environmental problems caused by small communities in Turkey. Pilot-scale treatment of a small community's wastewater was performed over a period of more than 2 years in order to show applicability of these systems. The present study involves removal of organic matter and suspended solids in serially operated horizontal (HFCW) and vertical (VFCW) sub-surface flow constructed wetlands. The pilot-scale wetland was constructed downstream of anaerobic reactors at the campus of TUBITAK-MRC. Anaerobically pretreated wastewater was introduced into this hybrid two-stage sub-surface flow wetland system (TSCW). Wastewater was first introduced into the horizontal sub-surface flow system and then the vertical flow system before being discharged. Recirculation of the effluent was tested in the system. When the recirculation ratio was 100%, average removal efficiencies for TSCW were 91 +/- 4% for COD, 83 +/- 10% for BOD and 96 +/- 3% for suspended solids with average effluent concentrations of 9 +/- 5 mg/L COD, 6 +/- 3 mg/L BOD and 1 mg/L for suspended solids. Comparing non-recirculation and recirculation periods, the lowest effluent concentrations were obtained with a 100% recirculation ratio. The effluent concentrations met the Turkish regulations for discharge limits of COD, BOD and TSS in each case. The study showed that a hybrid constructed wetland system with recirculation is a very effective method of obtaining very low effluent organic matter and suspended solids concentrations downstream of anaerobic pretreatment of domestic wastewaters in small communities.

Speciation, behaviour, and fate of mercury under oxy-fuel combustion conditions.

PubMed

Córdoba, Patricia; Maroto-Valer, M; Delgado, Miguel Angel; Diego, Ruth; Font, Oriol; Querol, Xavier

2016-02-01

The work presented here reports the first study in which the speciation, behaviour and fate of mercury (Hg) have been evaluated under oxy-fuel combustion at the largest oxy-Pulverised Coal Combustion (oxy-PCC) demonstration plant to date during routine operating conditions and partial exhaust flue gas re-circulation to the boiler. The effect of the CO2-rich flue gas re-circulation on Hg has also been evaluated. Results reveal that oxy-PCC operational conditions play a significant role on Hg partitioning and fate because of the continuous CO2-rich flue gas re-circulations to the boiler. Mercury escapes from the cyclone in a gaseous form as Hg(2+) (68%) and it is the prevalent form in the CO2-rich exhaust flue gas (99%) with lower proportions of Hg(0) (1.3%). The overall retention rate for gaseous Hg is around 12%; Hg(0) is more prone to be retained (95%) while Hg(2+) shows a negative efficiency capture for the whole installation. The negative Hg(2+) capture efficiencies are due to the continuous CO2-rich exhaust flue gas recirculation to the boiler with enhanced Hg contents. Calculations revealed that 44mg of Hg were re-circulated to the boiler as a result of 2183 re-circulations of CO2-rich flue gas. Especial attention must be paid to the role of the CO2-rich exhaust flue gas re-circulation to the boiler on the Hg enrichment in Fly Ashes (FAs). Copyright © 2015 Elsevier Inc. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Córdoba, Patricia, E-mail: pc247@hw.ac.uk; Maroto-Valer, M.; Delgado, Miguel Angel

The work presented here reports the first study in which the speciation, behaviour and fate of mercury (Hg) have been evaluated under oxy-fuel combustion at the largest oxy-Pulverised Coal Combustion (oxy-PCC) demonstration plant to date during routine operating conditions and partial exhaust flue gas re-circulation to the boiler. The effect of the CO{sub 2}-rich flue gas re-circulation on Hg has also been evaluated. Results reveal that oxy-PCC operational conditions play a significant role on Hg partitioning and fate because of the continuous CO{sub 2}-rich flue gas re-circulations to the boiler. Mercury escapes from the cyclone in a gaseous form asmore » Hg{sup 2+} (68%) and it is the prevalent form in the CO{sub 2}-rich exhaust flue gas (99%) with lower proportions of Hg{sup 0} (1.3%). The overall retention rate for gaseous Hg is around 12%; Hg{sup 0} is more prone to be retained (95%) while Hg{sup 2+} shows a negative efficiency capture for the whole installation. The negative Hg{sup 2+} capture efficiencies are due to the continuous CO{sub 2}-rich exhaust flue gas recirculation to the boiler with enhanced Hg contents. Calculations revealed that 44 mg of Hg were re-circulated to the boiler as a result of 2183 re-circulations of CO{sub 2}-rich flue gas. Especial attention must be paid to the role of the CO{sub 2}-rich exhaust flue gas re-circulation to the boiler on the Hg enrichment in Fly Ashes (FAs). - Highlights: • The fate of gaseous Hg has been evaluated under oxy-fuel combustion. • The Hg oxidation process is enhanced in CO{sub 2}-rich flue gas recirculation. • Hg{sup 2+} is the prevalent gas species in the CO{sub 2}-rich exhaust flue gas. • Hg{sup 2+}{sub (g)} shows a negative efficiency capture for the whole installation. • Especial attention must be paid to the Hg enrichment in Fly Ashes.« less

Ion energy distributions in a pulsed dual frequency inductively coupled discharge of Ar/CF{sub 4} and effect of duty ratio

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mishra, Anurag; Seo, Jin Seok; Kim, Tae Hyung

2015-08-15

Controlling time averaged ion energy distribution (IED) is becoming increasingly important in many plasma material processing applications for plasma etching and deposition. The present study reports the evolution of ion energy distributions with radio frequency (RF) powers in a pulsed dual frequency inductively discharge and also investigates the effect of duty ratio. The discharge has been sustained using two radio frequency, low (P{sub 2 MHz} = 2 MHz) and high (P{sub 13.56 MHz} = 13.56 MHz) at a pressure of 10 mTorr in argon (90%) and CF{sub 4} (10%) environment. The low frequency RF powers have been varied from 100 to 600 W, whereas the high frequency powers frommore » 200 to 1200 W. Typically, IEDs show bimodal structure and energy width (energy separation between the high and low energy peaks) increases with increasing P{sub 13.56 MHz}; however, it shows opposite trends with P{sub 2 MHz}. It has been observed that IEDs bimodal structure tends to mono-modal structure and energy peaks shift towards low energy side as duty ratio increases, keeping pulse power owing to mode transition (capacitive to inductive) constant.« less

Track Structure and the Biological Effectiveness of Accelerated Particles for the Induction of Chromosome Damage

NASA Technical Reports Server (NTRS)

George, K.; Hada, M.; Chappell, L.; Cucinotta, F. A.

2011-01-01

Track structure models predict that at a fixed value of LET, particles with lower charge number, Z will have a higher biological effectiveness compared to particles with a higher Z. In this report we investigated how track structure effects induction of chromosomal aberration in human cells. Human lymphocytes were irradiated in vitro with various energies of accelerated iron, silicon, neon, or titanium ions and chromosome damage was assessed in using three color FISH chromosome painting in chemically induced PCC samples collected a first cell division post irradiation. The LET values for these ions ranged from 30 to195 keV/micron. Of the particles studied, Neon ions have the highest biological effectiveness for induction of total chromosome damage, which is consistent with track structure model predictions. For complex-type exchanges 64 MeV/ u Neon and 450 MeV/u Iron were equally effective and induced the most complex damage. In addition we present data on chromosomes exchanges induced by six different energies of protons (5 MeV/u to 2.5 GeV/u). The linear dose response term was similar for all energies of protons suggesting that the effect of the higher LET at low proton energies is balanced by the production of nuclear secondaries from the high energy protons.

High Relative Biologic Effectiveness of Carbon Ion Radiation on Induction of Rat Mammary Carcinoma and its Lack of H-ras and Tp53 Mutations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Imaoka, Tatsuhiko; Nishimura, Mayumi; Kakinuma, Shizuko

2007-09-01

Purpose: The high relative biologic effectiveness (RBE) of high-linear energy transfer (LET) heavy-ion radiation has enabled powerful radiotherapy. The potential risk of later onset of secondary cancers, however, has not been adequately studied. We undertook the present study to clarify the RBE of therapeutic carbon ion radiation and molecular changes that occur in the rat mammary cancer model. Methods and Materials: We observed 7-8-week-old rats (ACI, F344, Wistar, and Sprague-Dawley) until 1 year of age after irradiation (0.05-2 Gy) with either 290 MeV/u carbon ions with a spread out Bragg peak (LET 40-90 keV/{mu}m) generated from the Heavy-Ion Medical Acceleratormore » in Chiba or {sup 137}Cs {gamma}-rays. Results: Carbon ions significantly induced mammary carcinomas in Sprague-Dawley rats but less so in other strains. The dose-effect relationship for carcinoma incidence in the Sprague-Dawley rats was concave downward, providing an RBE of 2 at a typical therapeutic dose per fraction. In contrast, {approx}10 should be considered for radiation protection at low doses. Immunohistochemically, 14 of 18 carcinomas were positive for estrogen receptor {alpha}. All carcinomas examined were free of common H-ras and Tp53 mutations. Importantly, lung metastasis (7%) was characteristic of carbon ion-irradiated rats. Conclusions: We found clear genetic variability in the susceptibility to carbon ion-induced mammary carcinomas. The high RBE for carbon ion radiation further supports the importance of precise dose localization in radiotherapy. Common point mutations in H-ras and Tp53 were not involved in carbon ion induction of rat mammary carcinomas.« less

High relative biologic effectiveness of carbon ion radiation on induction of rat mammary carcinoma and its lack of H-ras and Tp53 mutations.

PubMed

Imaoka, Tatsuhiko; Nishimura, Mayumi; Kakinuma, Shizuko; Hatano, Yukiko; Ohmachi, Yasushi; Yoshinaga, Shinji; Kawano, Akihiro; Maekawa, Akihiko; Shimada, Yoshiya

2007-09-01

The high relative biologic effectiveness (RBE) of high-linear energy transfer (LET) heavy-ion radiation has enabled powerful radiotherapy. The potential risk of later onset of secondary cancers, however, has not been adequately studied. We undertook the present study to clarify the RBE of therapeutic carbon ion radiation and molecular changes that occur in the rat mammary cancer model. We observed 7-8-week-old rats (ACI, F344, Wistar, and Sprague-Dawley) until 1 year of age after irradiation (0.05-2 Gy) with either 290 MeV/u carbon ions with a spread out Bragg peak (LET 40-90 keV/mum) generated from the Heavy-Ion Medical Accelerator in Chiba or (137)Cs gamma-rays. Carbon ions significantly induced mammary carcinomas in Sprague-Dawley rats but less so in other strains. The dose-effect relationship for carcinoma incidence in the Sprague-Dawley rats was concave downward, providing an RBE of 2 at a typical therapeutic dose per fraction. In contrast, approximately 10 should be considered for radiation protection at low doses. Immunohistochemically, 14 of 18 carcinomas were positive for estrogen receptor alpha. All carcinomas examined were free of common H-ras and Tp53 mutations. Importantly, lung metastasis (7%) was characteristic of carbon ion-irradiated rats. We found clear genetic variability in the susceptibility to carbon ion-induced mammary carcinomas. The high RBE for carbon ion radiation further supports the importance of precise dose localization in radiotherapy. Common point mutations in H-ras and Tp53 were not involved in carbon ion induction of rat mammary carcinomas.

Heavy metal removal using nanoscale zero-valent iron (nZVI): Theory and application.

PubMed

Li, Shaolin; Wang, Wei; Liang, Feipeng; Zhang, Wei-Xian

2017-01-15

Treatment of wastewater containing heavy metals requires considerations on simultaneous removal of different ions, system reliability and quick separation of reaction products. In this work, we demonstrate that nanoscale zero-valent iron (nZVI) is an ideal reagent for removing heavy metals from wastewater. Batch experiments show that nZVI is able to perform simultaneous removal of different heavy metals and arsenic; reactive nZVI in uniform dispersion brings rapid changes in solution E h , enabling a facile way for reaction regulation. Microscope characterizations and settling experiments suggest that nZVI serves as solid seeds that facilitate products separation. A treatment process consisting of E h -controlled nZVI reaction, gravitational separation and nZVI recirculation is then demonstrated. Long-term (>12 months) operation shows that the process achieves >99.5% removal of As, Cu and a number of other toxic elements. The E h -controlled reaction system sustains a highly-reducing condition in reactor and reduces nZVI dosage. The process produces effluent of stable quality that meets local discharge guidelines. The gravitational separator shows high efficacy of nZVI recovery and the recirculation improves nZVI material efficiency, resulting in extraordinarily high removal capacities ((245mg As+226 mg-Cu)/g-nZVI). The work provides proof that nanomaterials can offer truly green and cost-effective solutions for wastewater treatment. Copyright © 2016 Elsevier B.V. All rights reserved.

Synchronization stability and pattern selection in a memristive neuronal network.

PubMed

Wang, Chunni; Lv, Mi; Alsaedi, Ahmed; Ma, Jun

2017-11-01

Spatial pattern formation and selection depend on the intrinsic self-organization and cooperation between nodes in spatiotemporal systems. Based on a memory neuron model, a regular network with electromagnetic induction is proposed to investigate the synchronization and pattern selection. In our model, the memristor is used to bridge the coupling between the magnetic flux and the membrane potential, and the induction current results from the time-varying electromagnetic field contributed by the exchange of ion currents and the distribution of charged ions. The statistical factor of synchronization predicts the transition of synchronization and pattern stability. The bifurcation analysis of the sampled time series for the membrane potential reveals the mode transition in electrical activity and pattern selection. A formation mechanism is outlined to account for the emergence of target waves. Although an external stimulus is imposed on each neuron uniformly, the diversity in the magnetic flux and the induction current leads to emergence of target waves in the studied network.

Determination of the rare-earth elements in geological materials by inductively coupled plasma mass spectrometry

USGS Publications Warehouse

Lichte, F.E.; Meier, A.L.; Crock, J.G.

1987-01-01

A method of analysis of geological materials for the determination of the rare-earth elements using the Inductively coupled plasma mass spectrometric technique (ICP-MS) has been developed. Instrumental parameters and factors affecting analytical results have been first studied and then optimized. Samples are analyzed directly following an acid digestion, without the need for separation or preconcentration with limits of detection of 2-11 ng/g, precision of ?? 2.5% relative standard deviation, and accuracy comparable to inductively coupled plasma emission spectrometry and instrumental neutron activation analysis. A commercially available ICP-MS instrument is used with modifications to the sample introduction system, torch, and sampler orifice to reduce the effects of high salt content of sample solutions prepared from geologic materials. Corrections for isobaric interferences from oxide ions and other diatomic and triatomic ions are made mathematically. Special internal standard procedures are used to compensate for drift in metahmetal oxide ratios and sensitivity. Reference standard values are used to verify the accuracy and utility of the method.

Synchronization stability and pattern selection in a memristive neuronal network

NASA Astrophysics Data System (ADS)

Wang, Chunni; Lv, Mi; Alsaedi, Ahmed; Ma, Jun

2017-11-01

Spatial pattern formation and selection depend on the intrinsic self-organization and cooperation between nodes in spatiotemporal systems. Based on a memory neuron model, a regular network with electromagnetic induction is proposed to investigate the synchronization and pattern selection. In our model, the memristor is used to bridge the coupling between the magnetic flux and the membrane potential, and the induction current results from the time-varying electromagnetic field contributed by the exchange of ion currents and the distribution of charged ions. The statistical factor of synchronization predicts the transition of synchronization and pattern stability. The bifurcation analysis of the sampled time series for the membrane potential reveals the mode transition in electrical activity and pattern selection. A formation mechanism is outlined to account for the emergence of target waves. Although an external stimulus is imposed on each neuron uniformly, the diversity in the magnetic flux and the induction current leads to emergence of target waves in the studied network.

Induction of Hydrolytic Enzymes in Brassica campestris in Response to Pathovars of Xanthomonas campestris.

PubMed

Conrads-Strauch, J; Dow, J M; Milligan, D E; Parra, R; Daniels, M J

1990-05-01

Inoculation of mature leaves of turnip (Brassica campestris) with the incompatible Xanthomonas campestris pv vitians resulted in the induction of beta-1,3-glucanase and chitinase/lysozyme (CHL) activity. No increase in the basal activity of beta-1,3-glucanase was observed after inoculation of leaves with heat- or rifampicin-killed X. c. vitians, Escherichia coli, or sterile water. Inoculation with the compatible X. campestris pv campestris resulted in a slower induction of glucanase than that seen with X. c. vitians. In contrast, all bacteria caused an induction of CHL activity. One major beta-1,3-glucanase (molecular mass 36.5 kilodaltons, isoelectric point [pl] ~8.5) was purified from both inoculated and untreated leaves by ion-exchange chromatography. The enzyme degraded laminarin by an endo-glycolytic mechanism. Two major CHL isozymes (CHL 1 and CHL 2, molecular mass 30 kilodaltons and pl 9.4 and 10.2, respectively) were purified from X. c. vitians inoculated leaves by affinity chromatography on a chitin column followed by ion-exchange chromatography. Both enzymes degraded chitin by an endo-glycolytic mechanism although the ratio of lysozyme to chitinase specific activities for CHL 1 and CHL2 were different. The induction of CHL 1 was associated with the hypersensitive reaction caused by X. c. vitians whereas all other treatments induced largely CHL 2.

The contribution of inductive electric fields to particle energization in the inner magnetosphere

NASA Astrophysics Data System (ADS)

Ilie, R.; Toth, G.; Liemohn, M. W.; Chan, A. A.

2017-12-01

Assessing the relative contribution of potential versus inductive electric fields at the energization of the hot ion population in the inner magnetosphere is only possible by thorough examination of the time varying magnetic field and current systems using global modeling of the entire system. We present here a method to calculate the inductive and potential components of electric field in the entire magnetosphere region. This method is based on the Helmholtz vector decomposition of the motional electric field as calculated by the BATS-R-US model, and is subject to boundary conditions. This approach removes the need to trace independent field lines and lifts the assumption that the magnetic field lines can be treated as frozen in a stationary ionosphere. In order to quantify the relative contributions of potential and inductive electric fields at driving plasma sheet ions into the inner magnetosphere, we apply this method for the March 17th, 2013 geomagnetic storm. We present here the consequences of slow continuous changes in the geomagnetic field as well as the strong tail dipolarizations on the distortion of the near-Earth magnetic field and current systems. Our findings indicate that the inductive component of the electric field is comparable, and even higher at times than the potential component, suggesting that the electric field induced by the time varying magnetic field plays a crucial role in the overall particle energization in the inner magnetosphere.

Summary Report on the Navy Emergency Escape Breathing Device

DTIC Science & Technology

1983-08-08

recirculated cas. The device produces pure oxygen (02) and uses a venturi to recirculate unused and expired gases through the purifier. A rubber...passing the recirculated air through a lithium hydroxide (LiOH) scrubber . The scrubber reduces the CO. level by forming either lithium bicarbonate (LiSCO...transparent visor and an elastromeric neck seal; a chlorate candle-based 02 generator; an air purification filter or scrubberl and a venturi arrangement to

Recirculating Electron Accelerators with Noncircular Electron Orbits as Radiation Sources for Applications (a Review)

NASA Astrophysics Data System (ADS)

Dubinov, Alexander E.; Ochkina, Elena I.

2018-05-01

State-of-the-art compact recirculating electron accelerators operating at intermediate energies (tens of MeV) are reviewed. The acceleration schemes implemented in the rhodotron, ridgetron, fantron, and cylindertron machines are discussed. Major accelerator components such as the electron guns, accelerating cavities, and bending magnets are described. The parameters of currently operating recirculating accelerators are tabulated, and applications of these accelerators in different processes of irradiation are exemplified.

Picosecond Pulse Recirculation for High Average Brightness Thomson Scattering-based Gamma-ray Sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Semenov, V. A.

2009-06-12

Pulse recirculation has been successfully demonstrated with the interaction laser system of LLNL's Thomson-Radiated Extreme X-ray (T-REX) source. The recirculation increased twenty-eight times the intensity of the light coming out of the laser system, demonstrating the capability of increasing the gamma-ray flux emitted by T-REX. The technical approach demonstrated could conceivably increase the average gamma-ray flux output by up to a hundred times.

Beam dynamics simulation of a double pass proton linear accelerator

DOE PAGES

Hwang, Kilean; Qiang, Ji

2017-04-03

A recirculating superconducting linear accelerator with the advantage of both straight and circular accelerator has been demonstrated with relativistic electron beams. The acceleration concept of a recirculating proton beam was recently proposed and is currently under study. In order to further support the concept, the beam dynamics study on a recirculating proton linear accelerator has to be carried out. In this paper, we study the feasibility of a two-pass recirculating proton linear accelerator through the direct numerical beam dynamics design optimization and the start-to-end simulation. This study shows that the two-pass simultaneous focusing without particle losses is attainable including fullymore » 3D space-charge effects through the entire accelerator system.« less

High Resolution Studies of the Origins of Polyatomic Ions in Inductively Coupled Plasma-Mass Spectrometry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ferguson, Jill Wisnewski

2006-01-01

The inductively coupled plasma (ICP) is an atmospheric pressure ionization source. Traditionally, the plasma is sampled via a sampler cone. A supersonic jet develops behind the sampler, and this region is pumped down to a pressure of approximately one Torr. A skimmer cone is located inside this zone of silence to transmit ions into the mass spectrometer. The position of the sampler and skimmer cones relative to the initial radiation and normal analytical zones of the plasma is key to optimizing the useful analytical signal [1]. The ICP both atomizes and ionizes the sample. Polyatomic ions form through ion-molecule interactionsmore » either in the ICP or during ion extraction [l]. Common polyatomic ions that inhibit analysis include metal oxides (MO +), adducts with argon, the gas most commonly used to make up the plasma, and hydride species. While high resolution devices can separate many analytes from common interferences, this is done at great cost in ion transmission efficiency--a loss of 99% when using high versus low resolution on the same instrument [2]. Simple quadrupole devices, which make up the bulk of ICP-MS instruments in existence, do not present this option. Therefore, if the source of polyatomic interferences can be determined and then manipulated, this could potentially improve the figures of merit on all ICP-MS devices, not just the high resolution devices often utilized to study polyatomic interferences.« less

Influence of instrumental parameters on the kinetic energy of ions and plasma temperature for a hexapole collision/reaction-cell-based inductively coupled plasma quadrupole mass spectrometer.

PubMed

Favre, Georges; Brennetot, René; Chartier, Frédéric; Tortajada, Jeanine

2009-02-01

Inductively coupled plasma mass spectrometry (ICP-MS) is widely used in inorganic analytical chemistry for element and/or isotope ratio measurements. The presence of interferences, which is one of the main limitations of this method, has been addressed in recent years with the introduction of collision/reaction cell devices on ICP-MS apparatus. The study of ion-molecule reactions in the gas phase then became of great importance for the development of new analytical strategies. Knowing the kinetic energy and the electronic states of the ions prior to their entrance into the cell, i.e., just before they react, thereby constitutes crucial information for the interpretation of the observed reactivities. Such studies on an ICP-MS commonly used for routine analyses require the determination of the influence of different instrumental parameters on the energy of the ions and on the plasma temperature from where ions are sampled. The kinetic energy of ions prior to their entrance into the cell has been connected to the voltage applied to the hexapole according to a linear relationship determined from measurements of ion energy losses due to collisions with neutral gas molecules. The effects of the plasma forward power, sampling depth, and the addition of a torch shield to the ICP source were then examined. A decrease of the plasma potential due to the torch shielding, already mentioned in the literature, has been quantified in this study at about 3 V.

Laser ion source for heavy ion inertial fusion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Okamura, Masahiro

The proposed heavy ion inertial fusion (HIF) scenarios require ampere class low charge state ion beams of heavy species. A laser ion source (LIS) is recognized as one of the promising candidates of ion beam providers, since it can deliver high brightness heavy ion beams to accelerators. A design of LIS for the HIF depends on the accelerator structure and accelerator complex following the source. In this article, we discuss the specifications and design of an appropriate LIS assuming two major types of the accelerators: radio frequency (RF) high quality factor cavity type and non-resonant induction core type. We believemore » that a properly designed LIS satisfies the requirements of both types, however some issues need to be verified experimentally.« less

Laser ion source for heavy ion inertial fusion

DOE PAGES

Okamura, Masahiro

2018-01-10

The proposed heavy ion inertial fusion (HIF) scenarios require ampere class low charge state ion beams of heavy species. A laser ion source (LIS) is recognized as one of the promising candidates of ion beam providers, since it can deliver high brightness heavy ion beams to accelerators. A design of LIS for the HIF depends on the accelerator structure and accelerator complex following the source. In this article, we discuss the specifications and design of an appropriate LIS assuming two major types of the accelerators: radio frequency (RF) high quality factor cavity type and non-resonant induction core type. We believemore » that a properly designed LIS satisfies the requirements of both types, however some issues need to be verified experimentally.« less

Induction, transcription, synthesis, and adsorption of interleukin-1 by dialyzer membranes.

PubMed

Vaziri, N D; Wang, J; Cesario, T; Yousefi, S; Valenzuela, R; Carandang, G

1994-05-01

This study was designed to dissect the direct effect of dialyzer membrane on interleukin-1 (IL-1) induction from those of complement activation, mechanical stimulation, acetate/bicarbonate and endotoxin diffusion, and cell type interactions. To this end, a suspension of P388D1 murine macrophages in a complement-free culture medium containing 10% heat-inactivated serum, a closed-loop system consisting of tubing alone or with a hollow-fiber cuprammonium cellulose (CU) or polyacrylonitrile (PAN) dialyzer, and a roller pump were used. The dialysate compartment was filled with the same medium and capped. Cell suspension was recirculated at 300 mL/min for 3 h. Cells and supernates were separated, and adhering proteins were eluted. All samples tested negative for endotoxin. IL-1 mRNA was greatest with CU, followed by PAN and tubing alone. IL-1 in the supernate was greater with CU than with either tubing alone or PAN (P < 0.005; analysis of variance), which showed comparable values. IL-1 eluted from loops was greatest with PAN dialyzers, followed by sets with CU dialyzers and tubing alone (P < 0.001; analysis of variance). Thus, both CU and PAN membranes directly induce IL-1. However, avid adsorption by PAN attenuates the rise in circulating IL-1.

Age and Smoking Related Changes in Metal Ion Levels in Human Lens: Implications for Cataract Formation

PubMed Central

Langford-Smith, Alex; Tilakaratna, Viranga; Lythgoe, Paul R.; Clark, Simon J.; Bishop, Paul N.; Day, Anthony J.

2016-01-01

Age-related cataract formation is the primary cause of blindness worldwide and although treatable by surgical removal of the lens the majority of sufferers have neither the finances nor access to the medical facilities required. Therefore, a better understanding of the pathogenesis of cataract may identify new therapeutic targets to prevent or slow its progression. Cataract incidence is strongly correlated with age and cigarette smoking, factors that are often associated with accumulation of metal ions in other tissues. Therefore this study evaluated the age-related changes in 14 metal ions in 32 post mortem human lenses without known cataract from donors of 11 to 82 years of age by inductively coupled plasma mass spectrometry; smoking-related changes in 10 smokers verses 14 non-smokers were also analysed. A significant age-related increase in selenium and decrease in copper ions was observed for the first time in the lens tissue, where cadmium ion levels were also increased as has been seen previously. Aluminium and vanadium ions were found to be increased in smokers compared to non-smokers (an analysis that has only been carried out before in lenses with cataract). These changes in metal ions, i.e. that occur as a consequence of normal ageing and of smoking, could contribute to cataract formation via induction of oxidative stress pathways, modulation of extracellular matrix structure/function and cellular toxicity. Thus, this study has identified novel changes in metal ions in human lens that could potentially drive the pathology of cataract formation. PMID:26794210

Focused electron and ion beam systems

DOEpatents

Leung, Ka-Ngo; Reijonen, Jani; Persaud, Arun; Ji, Qing; Jiang, Ximan

2004-07-27

An electron beam system is based on a plasma generator in a plasma ion source with an accelerator column. The electrons are extracted from a plasma cathode in a plasma ion source, e.g. a multicusp plasma ion source. The beam can be scanned in both the x and y directions, and the system can be operated with multiple beamlets. A compact focused ion or electron beam system has a plasma ion source and an all-electrostatic beam acceleration and focusing column. The ion source is a small chamber with the plasma produced by radio-frequency (RF) induction discharge. The RF antenna is wound outside the chamber and connected to an RF supply. Ions or electrons can be extracted from the source. A multi-beam system has several sources of different species and an electron beam source.

Present status of numerical modeling of hydrogen negative ion source plasmas and its comparison with experiments: Japanese activities and their collaboration with experimental groups

NASA Astrophysics Data System (ADS)

Hatayama, A.; Nishioka, S.; Nishida, K.; Mattei, S.; Lettry, J.; Miyamoto, K.; Shibata, T.; Onai, M.; Abe, S.; Fujita, S.; Yamada, S.; Fukano, A.

2018-06-01

The present status of kinetic modeling of particle dynamics in hydrogen negative ion (H‑) source plasmas and their comparisons with experiments are reviewed and discussed with some new results. The main focus is placed on the following topics, which are important for the research and development of H‑ sources for intense and high-quality H‑ ion beams: (i) effects of non-equilibrium features of electron energy distribution function on volume and surface H‑ production, (ii) the origin of the spatial non-uniformity in giant multi-cusp arc-discharge H‑ sources, (iii) capacitive to inductive (E to H) mode transition in radio frequency-inductively coupled plasma H‑ sources and (iv) extraction physics of H‑ ions and beam optics, especially the present understanding of the meniscus formation in strongly electronegative plasmas (so-called ion–ion plasmas) and its effect on beam optics. For these topics, mainly Japanese modeling activities, and their domestic and international collaborations with experimental studies, are introduced with some examples showing how models have been improved and to what extent the modeling studies can presently contribute to improving the source performance. Close collaboration between experimental and modeling activities is indispensable for the validation/improvement of the modeling and its contribution to the source design/development.

Investigation of Microbunching Instabilities in Modern Recirculating Accelerators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tsai, Cheng

Particle accelerators are machines to accelerate and store charged particles, such as electrons or protons, to the energy levels for various scientific applications. A collection of charged particles usually forms a particle beam. There are three basic types of particle accelerators: linear accelerators (linac), storage-ring (or circular) accelerators, and recirculating accelerators. In a linac, particles are accelerated and pass through once along a linear or straight beamline. Storage-ring accelerators propel particles around a circular track and repetitively append the energy to the stored beam. The third type, also the most recent one in chronology, the recirculating accelerator, is designed tomore » accelerate the particle beam in a short section of linac, circulate the beam, and then either continue to accelerate for energy boost or decelerate it for energy recovery. The beam properties of a linac machine are set at best by the initial particle sources. For storage rings, the beam equilibria are instead determined by the overall machine design. The modern recirculating machines share with linacs the advantages to both accelerate and preserve the beam with high beam quality, as well as efficiently reuse the accelerating components. The beamline design in such a machine configuration can however be much more complicated than that of linacs. As modern accelerators push toward the high-brightness or high-intensity frontier by demanding particles in a highly charged bunch (about nano-Coulomb per bunch) to concentrate in an ever-decreasing beam phase space (transverse normalized emittance about 1 μm and relative energy spread of the order of 10^-5 in GeV beam energy), the interaction amongst particles via their self-generated electromagnetic fields can potentially lead to coherent instabilities of the beam and thus pose significant challenges to the machine design and operation. In the past decade and a half, microbunching instability (MBI) has been one of the most challenging issues for such high-brightness or high-intensity beam transport, as it would degrade lasing performance in the fourth-generation light sources, reduce cooling efficiency in electron cooling facilities, and compromise the luminosity of colliding beams in lepton or lepton-hadron colliders. The dissertation work will focus on the MBI in modern recirculating electron accelerators. It has been known that the collective interactions, the coherent synchrotron radiation (CSR) and the longitudinal space charge (LSC) forces, can drive MBI. The CSR effect is a collective phenomenon in which the electrons in a curved motion, e.g. a bending dipole, emit radiation at a scale comparable to the micro-bunched structure of the bunch distribution. The LSC effect stems from non-uniformity of the charge distribution, acts as plasma oscillation, and can eventually accumulate an amount of energy modulation when the beam traverses a long section of a beamline. MBI can be seeded by non-uniformity or shot noise of the beam, which originates from granularity of the elementary charge. Through the aforementioned collective effects, the modulation of the bunch sub-structure can be amplified and, once the beam-wave interaction formed a positive feedback, can result in MBI. The problem of MBI has been intensively studied for linac-based facilities and for storage-ring accelerators. However, systematic studies for recirculation machines are still very limited and form a knowledge gap. Because of the much more complicated machine configuration of the recirculating accelerators than that of linacs, the existing MBI analysis needs to be extended to accommodate the high-brightness particle beam transport in modern recirculating accelerators. This dissertation is focused on theoretical investigation of MBI in such machine configuration in the following seven themes: (1) Development and generalization of MBI theory The theoretical formulation has been extended so as to be applicable to a general linear beamline lattice including horizontal and vertical transport bending elements, and beam acceleration or deceleration. These featured generalizations are required for MBI analysis in recirculation accelerators. (2) Construction of CSR impedance models In addition to the steady-state CSR interaction, it has been found that the exit transient effect (or CSR drift) can even result in more serious MBI in high-brightness recirculation arcs. The onedimensional free-space CSR impedances, especially the exit transients, are derived. The steady-state CSR impedance is also extended to non-ultrarelativistic beam energy for MBI analysis of low-energy merger sections in recirculating accelerators. (3) Numerical implementation of the derived semi-analytical formulation This includes the development of a semi-analytical Vlasov solver for MBI analysis, and also benchmarking of the solver against massive particle tracking simulations. (4) Exploration of multistage amplification behavior of CSR microbunching development The CSR-induced MBI acts as an amplifier, which amplifies the sub-bunch modulation of a beam. The amplification is commonly quantified by the amplification gain. A beam transport system can be considered as a cascaded amplifier. Unlike the two-stage amplification of four-dipole bunch compressor chicanes employed in linacs, the recirculation arcs, which are usually constituted by several tens of bending magnets, show a distinguishing feature of up to six-stage microbunching amplification for our example arc lattices. That is, the maximal CSR amplification gain can be proportional to the peak bunch current up to sixth power. A method to compare lattice performance has been developed in terms of gain coefficients, which nearly depend on the lattice properties only. This method has also proven to be an effective way to quantify the current dependence of the maximal (5) Control of CSR MBI in multibend transport or recirculation arcs The existing mitigation schemes of MBI mostly aim to linac-based accelerators and may not be practical to the recirculating accelerator facilities. Thus a set of conditions for suppression of CSR MBI was proposed and examined for example lattices from low (~100 MeV) to high (~1 GeV) energies. (6) Study of more aspects of microbunched structures in beam phase spaces For a cascaded amplifier in circuit electronics, the total amplification gain can be estimated as the product of individual gains. In a beam transport line of an accelerator, the (scalar) gain multiplication was examined and found to under-estimate the overall microbunching amplification. The concept of gain matrix was developed, which includes the density, energy and transverse-longitudinal modulations in a beam phase space, and used to analyze MBI for a proposed recirculating machine. Throughout the gain matrix approach, it reasonably gives the upper limit of spectral MBI gain curves. This extended analysis can be employed to study multi-pass recirculation. (7) Study of MBI for magnetized beams Driven by a recent energy-recovery-linac based cooler design for electron cooling at Jefferson Lab Electron-Ion Collider Project, the generalized theoretical formulation for MBI to a transversely coupled beam has been developed and applied to this study. A magnetized beam in general features non-zero canonical angular momentum, thus considered to be a transversely coupled beam. A novel idea of utilizing magnetized beam transport was proposed for improvement of cooling efficiency and possible mitigation of collective effects. A concern of MBI regarding this design was studied and excluded. The large transverse beam size associated with the beam magnetization is found to help suppress MBI via the transverse-longitudinal correlation.« less

Principles of Induction Accelerators

NASA Astrophysics Data System (ADS)

Briggs*, Richard J.

The basic concepts involved in induction accelerators are introduced in this chapter. The objective is to provide a foundation for the more detailed coverage of key technology elements and specific applications in the following chapters. A wide variety of induction accelerators are discussed in the following chapters, from the high current linear electron accelerator configurations that have been the main focus of the original developments, to circular configurations like the ion synchrotrons that are the subject of more recent research. The main focus in the present chapter is on the induction module containing the magnetic core that plays the role of a transformer in coupling the pulsed power from the modulator to the charged particle beam. This is the essential common element in all these induction accelerators, and an understanding of the basic processes involved in its operation is the main objective of this chapter. (See [1] for a useful and complementary presentation of the basic principles in induction linacs.)

Contribution of seawater recirculation to submarine groundwater discharge and related nutrient fluxes in two tropical bays

NASA Astrophysics Data System (ADS)

Vautier, Camille; Dulaiova, Henrietta

2017-04-01

Hawaiian coastal waters suffer from excess terrestrial nutrient loading, most of which comes from submarine groundwater discharge (SGD). This study quantifies and distinguishes the role of the fresh terrestrial and tidally pumped salt water components of SGD into the nearshore zone of two reefs on the island of Oahu: Maunalua Bay and Kāneohe Bay. The two components of SGD are characterized using isotopic techniques, and the study mainly focuses on the less understood recirculation component. A two-step approach is implemented: first, a conceptual model of groundwater circulation is established; second, nutrient fluxes associated with seawater recirculation are quantified. Groundwater circulation through the beach berm is quantified and characterized using 222Rn and 224Ra activity measurements. Nutrient fluxes are obtained by coupling nutrient concentration measurements and discharge estimates. The isotopic signatures inform us about the influence of the tidal cycle on groundwater circulation. 222Rn, 224Ra, and δ18O isotopes are used to derive apparent ages of the infiltrated seawater and allow us to quantify recirculation rates. The method is also complemented with the use of silicate concentration as tracers of the recirculation process. The trends in apparent ages observed in pore water in Maunalua match previously published conceptual groundwater circulation models and show a sequentially aging pore water circulation loop. However, the ages obtained in Kāneohe suggest a different tidal pumping dynamic that lacks a circulation loop, perhaps resulting from the absence of freshwater discharge. Derived nutrient fluxes show that the autochthonous production of inorganic nitrogen and phosphorus that occurs during seawater recirculation has a significant impact on nutrient cycles in the nearshore areas of the bays. This result suggests that seawater recirculation should be taken into account in biogeochemical studies of coastal areas.

A concentrated solar cavity absorber with direct heat transfer through recirculating metallic particles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sarker, M. R. I., E-mail: islamrabiul@yahoo.com; Saha, Manabendra, E-mail: manabendra.saha@adelaide.edu.au, E-mail: manab04me@gmail.com; Beg, R. A.

A recirculating flow solar particle cavity absorber (receiver) is modeled to investigate the flow behavior and heat transfer characteristics of a novel developing concept. It features a continuous recirculating flow of non-reacting metallic particles (black silicon carbide) with air which are used as a thermal enhancement medium. The aim of the present study is to numerically investigate the thermal behavior and flow characteristics of the proposed concept. The proposed solar particle receiver is modeled using two phase discrete particle model (DPM), RNG k-flow model and discrete ordinate (DO) radiation model. Numerical analysis is carried out considering a solar receiver withmore » only air and the mixture of non-reacting particles and air as a heat transfer as well as heat carrying medium. The parametric investigation is conducted considering the incident solar flux on the receiver aperture and changing air flow rate and recirculation rate inside the receiver. A stand-alone feature of the recirculating flow solar particle receiver concept is that the particles are directly exposed to concentrated solar radiation monotonously through recirculating flow inside the receiver and results in efficient irradiation absorption and convective heat transfer to air that help to achieve high temperature air and consequently increase in thermal efficiency. This paper presents, results from the developed concept and highlights its flow behavior and potential to enhance the heat transfer from metallic particles to air by maximizing heat carrying capacity of the heat transfer medium. The imposed milestones for the present system will be helpful to understand the radiation absorption mechanism of the particles in a recirculating flow based receiver, the thermal transport between the particles, the air and the cavity, and the fluid dynamics of the air and particle in the cavity.« less

Removal of non-biodegradable organic matter from landfill leachates by adsorption.

PubMed

Rodríguez, J; Castrillón, L; Marañón, E; Sastre, H; Fernández, E

2004-01-01

Leachates produced at the La Zoreda landfill in Asturias, Spain, were recirculated through a simulated landfill pilot plant. Prior to recirculation, three loads of different amounts of Municipal Solid Waste (MSW) were added to the plant, forming in this way consecutive layers. When anaerobic digestion was almost completed, the leachates from the landfill were recirculated. After recirculation, a new load of MSW was added and two new recirculations were carried out. The organic load of the three landfill leachates recirculated through the anaerobic pilot plant decreased from initial values of 5108, 3782 and 2560 mg/l to values of between 1500 and 1600 mg/l. Despite achieving reductions in the organic load of the leachate, a residual organic load still remained that was composed of non-biodegradable organic constituents such as humic substances. Similar values of the chemical oxygen demand (COD) were obtained when the landfill leachate was treated by a pressurised anoxic-aerobic process followed by ultrafiltration. After recirculation through the pilot plant, physico-chemical treatment was carried out to reduce the COD of the leachate. The pH of the leachate was decreased to a value of 1.5 to precipitate the humic fraction, obtaining a reduction in COD of about 13.5%. The supernatant liquid was treated with activated carbon and different resins, XAD-8, XAD-4 and IR-120. Activated carbon presented the highest adsorption capacities, obtaining COD values for the treated leachate in the order of 200mg/l. Similar results were obtained when treating with activated carbon, the leachate from the biological treatment plant at the La Zoreda landfill; in this case without decreasing the pH.

Heat recirculating cooler for fluid stream pollutant removal

DOEpatents

Richards, George A.; Berry, David A.

2008-10-28

A process by which heat is removed from a reactant fluid to reach the operating temperature of a known pollutant removal method and said heat is recirculated to raise the temperature of the product fluid. The process can be utilized whenever an intermediate step reaction requires a lower reaction temperature than the prior and next steps. The benefits of a heat-recirculating cooler include the ability to use known pollutant removal methods and increased thermal efficiency of the system.

Analysis of rapid increase in the plasma density during the ramp-up phase in a radio frequency negative ion source by large-scale particle simulation

NASA Astrophysics Data System (ADS)

Yasumoto, M.; Ohta, M.; Kawamura, Y.; Hatayama, A.

2014-02-01

Numerical simulations become useful for the developing RF-ICP (Radio Frequency Inductively Coupled Plasma) negative ion sources. We are developing and parallelizing a two-dimensional three velocity electromagnetic Particle-In-Cell code. The result shows rapid increase in the electron density during the density ramp-up phase. A radial electric field due to the space charge is produced with increase in the electron density and the electron transport in the radial direction is suppressed. As a result, electrons stay for a long period in the region where the inductive electric field is strong, and this leads efficient electron acceleration and a rapid increasing of the electron density.

An advanced anaerobic biofilter with effluent recirculation for phenol removal and methane production in treatment of coal gasification wastewater.

PubMed

Li, Yajie; Tabassum, Salma; Zhang, Zhenjia

2016-09-01

An advanced anaerobic biofilter (AF) was introduced for the treatment of coal gasification wastewater (CGW), and effluent recirculation was adopted to enhance phenol removal and methane production. The results indicated that AF was reliable in treating diluted CGW, while its efficiency and stability were seriously reduced when directly treating raw CGW. However, its performance could be greatly enhanced by effluent recirculation. Under optimal effluent recirculation of 0.5 to the influent, concentrations of chemical oxygen demand (COD) and total phenol in the effluent could reach as low as 234.0 and 14.2mg/L, respectively. Also, the rate of methane production reached 169.0mLCH4/L/day. Though CGW seemed to restrain the growth of anaerobic microorganisms, especially methanogens, the inhibition was temporary and reversible, and anaerobic bacteria presented strong tolerance. The activities of methanogens cultivated in CGW could quickly recover on feeding with glucose wastewater (GW). However, the adaptability of anaerobic bacteria to the CGW was very poor and the activity of methanogens could not be improved by long-term domestication. By analysis using the Haldane model, it was further confirmed that high effluent recirculation could result in high activity for hydrolytic bacteria and substrate affinity for toxic matters, but only suitable effluent recirculation could result in high methanogenic activity. Copyright © 2016. Published by Elsevier B.V.

Characterization of a joint recirculation of concentrated leachate and leachate to landfills with a microaerobic bioreactor for leachate treatment.

PubMed

He, Ruo; Wei, Xiao-Meng; Tian, Bao-Hu; Su, Yao; Lu, Yu-Lan

2015-12-01

With comparison of a traditional landfill, a joint recirculation of concentrated leachate and leachate to landfills with or without a microaerobic reactor for leachate treatment was investigated in this study. The results showed that the joint recirculation of concentrated leachate and leachate with a microaerobic reactor for leachate treatment could not only utilize the microaerobic reactor to buffer the fluctuation of quality and quantity of leachate during landfill stabilization, but also reduce the inhibitory effect of acidic pH and high concentrations of ammonium in recycled liquid on microorganisms and accelerate the degradation of landfilled waste. After 390 days of operation, the discharge of COD and total nitrogen (TN) from the landfill with leachate pretreatment by a microaerobic reactor was 7.4 and 0.9 g, respectively, which accounted for 0.7% and 2.6% of COD, 1.9% and 7.5% of the TN discharge from the landfills without recirculation and directly recirculated with leachate and concentrated leachate, respectively. The degradation of the organic matter and biodegradable matter (BDM) in the landfill reactors could fit well with the first-order kinetics. The highest degradation of the organic matter and BDM was observed in the joint recirculation system with a microaerobic reactor for leachate treatment with the degradation constant of the first-order kinetics of 0.001 and 0.002. Copyright © 2015 Elsevier Ltd. All rights reserved.

Evaluation of mRNA expression levels and electrophysiological function of neuron-like cells derived from canine bone marrow stromal cells.

PubMed

Nakano, Rei; Edamura, Kazuya; Sugiya, Hiroshi; Narita, Takanori; Okabayashi, Ken; Moritomo, Tadaaki; Teshima, Kenji; Asano, Kazushi; Nakayama, Tomohiro

2013-10-01

To investigate the in vitro differentiation of canine bone marrow stromal cells (BMSCs) into functional, mature neurons. Bone marrow from 6 adult dogs. BMSCs were isolated from bone marrow and chemically induced to develop into neurons. The morphology of the BMSCs during neuronal induction was monitored, and immunocytochemical analyses for neuron markers were performed after the induction. Real-time PCR methods were used to evaluate the mRNA expression levels of markers for neural stem or progenitor cells, neurons, and ion channels, and western blotting was used to assess the expression of neuronal proteins before and after neuronal induction. The electrophysiological properties of the neuron-like cells induced from canine BMSCs were evaluated with fluorescent dye to monitor Ca(2)+ influx. Canine BMSCs developed a neuron-like morphology after neuronal induction. Immunocytochemical analysis revealed that these neuron-like cells were positive for neuron markers. After induction, the cells' mRNA expression levels of almost all neuron and ion channel markers increased, and the protein expression levels of nestin and neurofilament-L increased significantly. However, the neuron-like cells derived from canine BMSCs did not have the Ca(2)+ influx characteristic of spiking neurons. Although canine BMSCs had neuron-like morphological and biochemical properties after induction, they did not develop the electrophysiological characteristics of neurons. Thus, these results have suggested that canine BMSCs could have the capacity to differentiate into a neuronal lineage, but the differentiation protocol used may have been insufficient to induce development into functional neurons.

[HPLC-ESI-MS(n) analysis of the water soluble extracts of Fructus Choerospondiatis].

PubMed

Shi, Run-ju; Dai, Yun; Fang, Min-feng; Zhao, Xin; Zheng, Jian-bin; Zheng, Xiao-hui

2007-03-01

To establish an HPLC-ESI-MS(n) method for analyzing the chemical ingredients in the water soluble extracts of Fructus Choerospondiatis. Water-solvable extracts of Fructus Choerospondiatis are obtained by heating recirculation. Multi-stage reaction mode (MRM) of the HPLC-ESI-MS(n) was used to determine the content of Gallic acid, the MS(n) technology was used to obtain the information of characteristic multistage fragment ions so as to identify the chemical structure of peaks in the total current spectrum. Eleven compounds were identified, and one of them is a new unknown ingredient. The method, which has high recovery and specificity, can offer the experimental evidences for the further research of the chemical ingredients extracted from the Fructus Choerospondiatis.

Influence of airflow rate and substrate nature on heterogeneous struvite precipitation.

PubMed

Saidou, H; Ben Moussa, S; Ben Amor, M

2009-01-01

In wastewater treatment plants a hard scale consisting of struvite crystals can be formed, in pipes and recirculation pumps, during anaerobic digestion of wastewater. This study was conducted to evaluate the effect of airflow rate and substrate nature on nucleation type, induction period and supersaturation coefficient during struvite precipitation. A crystallization reactor similar to that designed for calcium carbonate precipitation was used. The pH of synthetic wastewater solution was increased by air bubbling. Experimental results indicated that the airflow increased heterogeneous precipitation of struvite. The susceptibility to scale formation was more important on polyamide and polyvinyl chloride than on stainless steel. In all cases, X-ray diffraction and infrared spectroscopy showed that the precipitated solid phase was solely struvite. No difference in crystal morphology was observed. However, at similar experimental conditions, the particle size of struvite was higher for stainless-steel material than that for plastic materials.

Suction-recirculation device for stabilizing particle flows within a solar powered solid particle receiver

DOEpatents

Kolb, Gregory J [Albuquerque, NM

2012-02-07

A suction-recirculation device for stabilizing the flow of a curtain of blackened heat absorption particles falling inside of a solar receiver with an open aperture. The curtain of particles absorbs the concentrated heat from a solar mirror array reflected up to the receiver on a solar power tower. External winds entering the receiver at an oblique angle can destabilize the particle curtain and eject particles. A fan and ductwork is located behind the back wall of the receiver and sucks air out through an array of small holes in the back wall. Any entrained particles are separated out by a conventional cyclone device. Then, the air is recirculated back to the top of the receiver by injecting the recycled air through an array of small holes in the receiver's ceiling and upper aperture front wall. Since internal air is recirculated, heat losses are minimized and high receiver efficiency is maintained. Suction-recirculation velocities in the range of 1-5 m/s are sufficient to stabilize the particle curtain against external wind speeds in excess of 10 m/s.

Recirculation zone length in renal artery is affected by flow spirality and renal-to-aorta flow ratio.

PubMed

Javadzadegan, Ashkan; Fulker, David; Barber, Tracie

2017-07-01

Haemodynamic perturbations such as flow recirculation zones play a key role in progression and development of renal artery stenosis, which typically originate at the aorta-renal bifurcation. The spiral nature of aortic blood flow, division of aortic blood flow in renal artery as well as the exercise conditions have been shown to alter the haemodynamics in both positive and negative ways. This study focuses on the combinative effects of spiral component of blood flow, renal-to-aorta flow ratio and the exercise conditions on the size and distribution of recirculation zones in renal branches using computational fluid dynamics technique. Our findings show that the recirculation length was longest when the renal-to-aorta flow ratio was smallest. Spiral flow and exercise conditions were found to be effective in reducing the recirculation length in particular in small renal-to-aorta flow ratios. These results support the hypothesis that in renal arteries with small flow ratios where a stenosis is already developed an artificially induced spiral flow within the aorta may decelerate the progression of stenosis and thereby help preserve kidney function.

Wall shear stress characterization of a 3D bluff-body separated flow

NASA Astrophysics Data System (ADS)

Fourrié, Grégoire; Keirsbulck, Laurent; Labraga, Larbi

2013-10-01

Efficient flow control strategies aimed at reducing the aerodynamic drag of road vehicles require a detailed knowledge of the reference flow. In this work, the flow around the rear slanted window of a generic car model was experimentally studied through wall shear stress measurements using an electrochemical method. The mean and fluctuating wall shear stress within the wall impact regions of the recirculation bubble and the main longitudinal vortex structures which develop above the rear window are presented. Correlations allow a more detailed characterization of the recirculation phenomenon within the separation bubble. In the model symmetry plane the recirculation structure compares well with simpler 2D configurations; specific lengths, flapping motion and shedding of large-scale vortices are observed, these similarities diminish when leaving the middle plane due to the strong three-dimensionality of the flow. A specific attention is paid to the convection processes occurring within the recirculation: a downstream convection velocity is observed, in accordance with 2D recirculations from the literature, and an upstream convection is highlighted along the entire bubble length which has not been underlined in some previous canonical configurations.

Experimental investigation of a local recirculation photobioreactor for mass cultures of photosynthetic microorganisms.

PubMed

Moroni, Monica; Cicci, Agnese; Bravi, Marco

2014-04-01

The present work deals with the experimental fluid mechanics analysis of a wavy-bottomed cascade photobioreactor, to characterize the extent and period of recirculatory and straight-flowing streams establishing therein as a function of reactor inclination and liquid flow rate. The substream characterization via Feature Tracking (FT) showed that a local recirculation zone establishes in each vane only at inclinations ≤6° and that its location changes from the lower (≤3°) to the upper part of each vane (6°). A straight-flowing stream flows opposite (above or below) the local recirculation stream. The recirculation time ranges from 0.86 s to 0.23 s, corresponding, respectively, to the minimum flow rate at the minimum inclination and to the maximum flow rate at the maximum inclination where recirculation was observed. The increase of photosynthetic activity, resulting from the entailed "flash effect", was estimated to range between 102 and 113% with respect to equivalent tubular and bubble column photobioreactors. Copyright © 2013 Elsevier Ltd. All rights reserved.

Method and apparatus for control of coherent synchrotron radiation effects during recirculation with bunch compression

DOEpatents

Douglas, David R; Tennant, Christopher

2015-11-10

A modulated-bending recirculating system that avoids CSR-driven breakdown in emittance compensation by redistributing the bending along the beamline. The modulated-bending recirculating system includes a) larger angles of bending in initial FODO cells, thereby enhancing the impact of CSR early on in the beam line while the bunch is long, and 2) a decreased bending angle in the final FODO cells, reducing the effect of CSR while the bunch is short. The invention describes a method for controlling the effects of CSR during recirculation and bunch compression including a) correcting chromatic aberrations, b) correcting lattice and CSR-induced curvature in the longitudinal phase space by compensating T.sub.566, and c) using lattice perturbations to compensate obvious linear correlations x-dp/p and x'-dp/p.

A new mechanism for periodic bursting of the recirculation region in the flow through a sudden expansion in a circular pipe

NASA Astrophysics Data System (ADS)

Lebon, Benoit; Nguyen, Minh Quan; Peixinho, Jorge; Shadloo, Mostafa Safdari; Hadjadj, Abdellah

2018-03-01

We report the results of a combined experimental and numerical study of specific finite-amplitude disturbances for transition to turbulence in the flow through a circular pipe with a sudden expansion. The critical amplitude thresholds for localized turbulent patch downstream of the expansion scale with the Reynolds number with a power law exponent of -2.3 for experiments and -2.8 for simulations. A new mechanism for the periodic bursting of the recirculation region is uncovered where the asymmetric recirculation flow develops a periodic dynamics: a secondary recirculation breaks the symmetry along the pipe wall and bursts into localized turbulence, which travels downstream and relaminarises. Flow visualizations show a simple flow pattern of three waves forming, growing, and bursting.

The effects of leachate recirculation with supplemental water addition on methane production and waste decomposition in a simulated tropical landfill.

PubMed

Sanphoti, N; Towprayoon, S; Chaiprasert, P; Nopharatana, A

2006-10-01

In order to increase methane production efficiency, leachate recirculation is applied in landfills to increase moisture content and circulate organic matter back into the landfill cell. In the case of tropical landfills, where high temperature and evaporation occurs, leachate recirculation may not be enough to maintain the moisture content, therefore supplemental water addition into the cell is an option that could help stabilize moisture levels as well as stimulate biological activity. The objectives of this study were to determine the effects of leachate recirculation and supplemental water addition on municipal solid waste decomposition and methane production in three anaerobic digestion reactors. Anaerobic digestion with leachate recirculation and supplemental water addition showed the highest performance in terms of cumulative methane production and the stabilization period time required. It produced an accumulated methane production of 54.87 l/kg dry weight of MSW at an average rate of 0.58 l/kg dry weight/d and reached the stabilization phase on day 180. The leachate recirculation reactor provided 17.04 l/kg dry weight at a rate of 0.14l/kg dry weight/d and reached the stabilization phase on day 290. The control reactor provided 9.02 l/kg dry weight at a rate of 0.10 l/kg dry weight/d, and reached the stabilization phase on day 270. Increasing the organic loading rate (OLR) after the waste had reached the stabilization phase made it possible to increase the methane content of the gas, the methane production rate, and the COD removal. Comparison of the reactors' efficiencies at maximum OLR (5 kgCOD/m(3)/d) in terms of the methane production rate showed that the reactor using leachate recirculation with supplemental water addition still gave the highest performance (1.56 l/kg dry weight/d), whereas the leachate recirculation reactor and the control reactor provided 0.69 l/kg dry weight/d and 0.43 l/kg dry weight/d, respectively. However, when considering methane composition (average 63.09%) and COD removal (average 90.60%), slight differences were found among these three reactors.

Bayesian Integration and Characterization of Composition C-4 Plastic Explosives Based on Time-of-Flight Secondary Ion Mass Spectrometry and Laser Ablation-Inductively Coupled Plasma Mass Spectrometry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mahoney, Christine M.; Kelly, Ryan T.; Alexander, M. L.

Key elements regarding the use of non-radioactive ionization sources will be presented as related to explosives detection by mass spectrometry and ion mobility spectrometry. Various non-radioactive ionization sources will be discussed along with associated ionization mechanisms pertaining to specific sample types.

Interpretation of mutation induction by accelerated heavy ions in bacteria

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kozubek, S.; Ryznar, L.; Horneck, G.

In this report, a quantitative interpretation of mutation induction cross sections by heavy charged particles in bacterial cells is presented. The approach is based on the calculation of the fraction of energy deposited by indirect hits in the sensitive structure. In these events the particle does not pass through the sensitive volume, but this region is hit by {delta} rays. Four track structure models, developed by Katz, Chatterjee et al, Kiefer and Straaten and Kudryashov et al., respectively, were used for the calculations. With the latter two models, very good agreement of the calculations with experimental results on mutagenesis inmore » bacteria was obtained. Depending on the linear energy transfer (LET{infinity}) of the particles, two different modes of mutagenic action of heavy ions are distinguished: {open_quotes}{delta}-ray mutagenesis,{close_quotes} which is related to those radiation qualities that preferentially kill the cells in direct hits (LET{infinity} {ge} 100 keV/{mu}m), and {open_quotes}track core mutagenesis,{close_quotes} which arises from direct hits and is observed for lighter ions or ions with high energy (LET{infinity} {le} 100 keV/{mu}m). 37 refs., 6 figs., 1 tab.« less

New Fusion Concept Using Coaxial Passing Through Each Other Self-focusing Colliding Beams (Invention)

NASA Astrophysics Data System (ADS)

Chikvashvili, Ioseb

2011-10-01

In proposed Concept it is offered to use two ion beams directed coaxially at the same direction but with different velocities (center-of-mass collision energy should be sufficient for fusion), to direct oppositely the relativistic electron beam for only partial compensation of positive space charge and for allowing the combined beam's pinch capability, to apply the longitudinal electric field for compensation of alignment of velocities of reacting particles and also for compensation of energy losses of electrons via Bremsstrahlung. On base of Concept different types of reactor designs can be realized: Linear and Cyclic designs. In the simplest embodiment the Cyclic Reactor (design) may include: betatron type device (circular store of externally injected particles - induction accelerator), pulse high-current relativistic electron injector, pulse high-current slower ion injector, pulse high-current faster ion injector and reaction products extractor. Using present day technologies and materials (or a reasonable extrapolation of those) it is possible to reach: for induction linear injectors (ions&electrons) - currents of thousands A, repeatability - up to 10Hz, the same for high-current betatrons (FFAG, Stellatron, etc.). And it is possible to build the fusion reactor using the proposed Method just today.

Simultaneous extraction and preconcentration of uranium and thorium in aqueous samples by new modified mesoporous silica prior to inductively coupled plasma optical emission spectrometry determination.

PubMed

Yousefi, Seyed Reza; Ahmadi, Seyed Javad; Shemirani, Farzaneh; Jamali, Mohammad Reza; Salavati-Niasari, Masoud

2009-11-15

A new synthesized modified mesoporous silica (MCM-41) using 5-nitro-2-furaldehyde (fural) was applied as an effective sorbent for the solid phase extraction of uranium(VI) and thorium(IV) ions from aqueous solution for the measurement by inductively coupled plasma optical emission spectrometry (ICP OES). The influences of some analytical parameters on the quantitative recoveries of the analyte ions were investigated in batch method. Under optimal conditions, the analyte ions were sorbed by the sorbent at pH 5.5 and then eluted with 1.0 mL of 1.0 mol L(-1) HNO(3). The preconcentration factor was 100 for a 100mL sample volume. The limits of detection (LOD) obtained for uranium(VI) and thorium(IV) were 0.3 microg L(-1). The maximum sorption capacity of the modified MCM-41 was found to be 47 and 49 mg g(-1) for uranium(VI) and thorium(IV), respectively. The sorbent exhibited good stability, reusability, high adsorption capacity and fast rate of equilibrium for sorption/desorption of uranium and thorium ions. The applicability of the synthesized sorbent was examined using CRM and real water samples.

Ion Clouds in the Inductively Coupled Plasma Torch: A Closer Look through Computations.

PubMed

Aghaei, Maryam; Lindner, Helmut; Bogaerts, Annemie

2016-08-16

We have computationally investigated the introduction of copper elemental particles in an inductively coupled plasma torch connected to a sampling cone, including for the first time the ionization of the sample. The sample is inserted as liquid particles, which are followed inside the entire torch, i.e., from the injector inlet up to the ionization and reaching the sampler. The spatial position of the ion clouds inside the torch as well as detailed information on the copper species fluxes at the position of the sampler orifice and the exhausts of the torch are provided. The effect of on- and off-axis injection is studied. We clearly show that the ion clouds of on-axis injected material are located closer to the sampler with less radial diffusion. This guarantees a higher transport efficiency through the sampler cone. Moreover, our model reveals the optimum ranges of applied power and flow rates, which ensure the proper position of ion clouds inside the torch, i.e., close enough to the sampler to increase the fraction that can enter the mass spectrometer and with minimum loss of material toward the exhausts as well as a sufficiently high plasma temperature for efficient ionization.

Biodosimetry of heavy ions by interphase chromosome painting

NASA Astrophysics Data System (ADS)

Durante, M.; Kawata, T.; Nakano, T.; Yamada, S.; Tsujii, H.

1998-11-01

We report measurements of chromosomal aberrations in peripheral blood lymphocytes from cancer patients undergoing radiotherapy treatment. Patients with cervix or esophageal cancer were treated with 10 MV X-rays produced at a LINAC accelerator, or high-energy carbon ions produced at the HIMAC accelerator at the National Institute for Radiological Sciences (NIRS) in Chiba. Blood samples were obtained before, during, and after the radiation treatment. Chromosomes were prematurely condensed by incubation in calyculin A. Aberrations in chromosomes 2 and 4 were scored after fluorescence in situ hybridization with whole-chromosome probes. Pre-treatment samples were exposed in vitro to X-rays, individual dose-response curves for the induction of chromosomal aberrations were determined, and used as calibration curves to calculate the effective whole-body dose absorbed during the treatment. This calculated dose, based on the calibration curve relative to the induction of reciprocal exchanges, has a sharp increase after the first few fractions of the treatment, then saturates at high doses. Although carbon ions are 2-3 times more effective than X-rays in tumor sterilization, the effective dose was similar to that of X-ray treatment. However, the frequency of complex-type chromosomal exchanges was much higher for patients treated with carbon ions than X-ray.

Evaluation of power transfer efficiency for a high power inductively coupled radio-frequency hydrogen ion source

NASA Astrophysics Data System (ADS)

Jain, P.; Recchia, M.; Cavenago, M.; Fantz, U.; Gaio, E.; Kraus, W.; Maistrello, A.; Veltri, P.

2018-04-01

Neutral beam injection (NBI) for plasma heating and current drive is necessary for International Thermonuclear Experimental reactor (ITER) tokamak. Due to its various advantages, a radio frequency (RF) driven plasma source type was selected as a reference ion source for the ITER heating NBI. The ITER relevant RF negative ion sources are inductively coupled (IC) devices whose operational working frequency has been chosen to be 1 MHz and are characterized by high RF power density (˜9.4 W cm-3) and low operational pressure (around 0.3 Pa). The RF field is produced by a coil in a cylindrical chamber leading to a plasma generation followed by its expansion inside the chamber. This paper recalls different concepts based on which a methodology is developed to evaluate the efficiency of the RF power transfer to hydrogen plasma. This efficiency is then analyzed as a function of the working frequency and in dependence of other operating source and plasma parameters. The study is applied to a high power IC RF hydrogen ion source which is similar to one simplified driver of the ELISE source (half the size of the ITER NBI source).

A novel route for the removal of bodily heavy metal lead (II)

NASA Astrophysics Data System (ADS)

Huang, Weirong; Zhang, Penghua; Xu, Hui; Chang, Shengli; He, Yongju; Wang, Fei; Liang, Gaowei

2015-09-01

The lead ion concentration in bile is considerably higher than in blood, and bile is released into the alimentary tract. Thiol-modified SBA-15 administered orally can combine with lead ions in the alimentary tract. In this paper, the in vitro lead absorption of bile was investigated. This thiol-modified SBA-15 material was used in pharmacodynamics studies on rabbits. The result that the lead content in faeces was notably higher indicates that thiol-modified SBA-15 can efficiently remove lead. The mechanism could include the following: thiol-modified SBA-15 material cuts off the heavy metal lead recirculation in the process of bile enterohepatic circulation by chelating the lead in the alimentary tract, causing a certain proportion of lead to be removed by the thiol mesoporous material, and the lead is subsequently egested out of the body in faeces. The results indicate that this material might be a potential non-injection material for the removal bodily heavy metal lead in the alimentary tract. This material may also be a useful means of lead removal, especially for non-acute sub-poisoning symptoms.

Evaluation of Nickel and Chromium Ion Release During Fixed Orthodontic Treatment Using Inductively Coupled Plasma-Mass Spectrometer: An In Vivo Study

PubMed Central

Nayak, Rabindra S; Khanna, Bharti; Pasha, Azam; Vinay, K; Narayan, Anjali; Chaitra, K

2015-01-01

Background: Fixed orthodontic appliances with the use of stainless steel brackets and archwires made of nitinol have a corrosive potential in the oral environment. Nickel and chromium ions released from these appliances act as allergens apart from being cytotoxic, mutagenic and carcinogenic in smaller quantities in the range of nanograms. This study was done to evaluate the release of nickel and chromium ions from orthodontic appliances in the oral cavity using Inductively Coupled Plasma-Mass Spectrometer (ICP-MS). Materials and Methods: Saliva samples from 30 orthodontic patients undergoing treatment with 0.022″ MBT mechanotherapy were collected prior to commencement of treatment, after initial aligning wires and after 10-12 months of treatment. Salivary nickel and chromium ion concentration was measured in parts per billion (ppb) using ICP-MS. Results: Mean, standard deviation and range were computed for the concentrations of ions obtained. Results analyzed using ANOVA indicated a statistically significant increase of 10.35 ppb in nickel ion concentration and 33.53 ppb in chromium ion concentration after initial alignment. The ionic concentration at the end of 10-12 months of treatment showed a statistically significant increase in of 17.92 ppb for chromium and a statistically insignificant decrease in nickel ion concentration by 1.58 ppb. Pearson’s correlation coefficient showed a positive correlation for an increase in nickel concentration after aligning, but not at the end of 10-12 months. A positive correlation was seen for an increase in chromium ion concentration at both time intervals. Conclusion: Nickel and chromium ion concentration in saliva even though below the recommended daily allowance should not be ignored in light of the new knowledge regarding effects of these ions at the molecular level and the allergic potential. Careful and detailed medical history of allergy is essential. Nickel free alternatives should form an essential part of an orthodontist’s inventory. PMID:26464533

Evaluation of Nickel and Chromium Ion Release During Fixed Orthodontic Treatment Using Inductively Coupled Plasma-Mass Spectrometer: An In Vivo Study.

PubMed

Nayak, Rabindra S; Khanna, Bharti; Pasha, Azam; Vinay, K; Narayan, Anjali; Chaitra, K

2015-08-01

Fixed orthodontic appliances with the use of stainless steel brackets and archwires made of nitinol have a corrosive potential in the oral environment. Nickel and chromium ions released from these appliances act as allergens apart from being cytotoxic, mutagenic and carcinogenic in smaller quantities in the range of nanograms. This study was done to evaluate the release of nickel and chromium ions from orthodontic appliances in the oral cavity using Inductively Coupled Plasma-Mass Spectrometer (ICP-MS). Saliva samples from 30 orthodontic patients undergoing treatment with 0.022″ MBT mechanotherapy were collected prior to commencement of treatment, after initial aligning wires and after 10-12 months of treatment. Salivary nickel and chromium ion concentration was measured in parts per billion (ppb) using ICP-MS. Mean, standard deviation and range were computed for the concentrations of ions obtained. Results analyzed using ANOVA indicated a statistically significant increase of 10.35 ppb in nickel ion concentration and 33.53 ppb in chromium ion concentration after initial alignment. The ionic concentration at the end of 10-12 months of treatment showed a statistically significant increase in of 17.92 ppb for chromium and a statistically insignificant decrease in nickel ion concentration by 1.58 ppb. Pearson's correlation coefficient showed a positive correlation for an increase in nickel concentration after aligning, but not at the end of 10-12 months. A positive correlation was seen for an increase in chromium ion concentration at both time intervals. Nickel and chromium ion concentration in saliva even though below the recommended daily allowance should not be ignored in light of the new knowledge regarding effects of these ions at the molecular level and the allergic potential. Careful and detailed medical history of allergy is essential. Nickel free alternatives should form an essential part of an orthodontist's inventory.

Induction of hepatic and renal ornithine decarboxylase by cobalt and other metal ions in rats.

PubMed Central

Yoshida, T; Numazawa, S; Kuroiwa, Y

1986-01-01

We previously showed that Cd2+ is able to induce hepatic and renal ornithine decarboxylase (ODC). In addition to Cd2+, the administration of Co2+ and other metal ions such as Se2+, Zn2+ and Cr2+ produced a significant increase of hepatic and/or renal ODC activity. Of the metal ions used in this study, Co2+ produced the greatest increase of ODC activity. The maximum increases in hepatic and renal ODC activity, to respectively 70 and 14 times the control values in male rats, were observed 6 h after the administration of Co2+. A similar response was seen in the liver, but not in the kidney, of female rats. Thereafter, ODC activity gradually returned to control values in the liver, but it was profoundly decreased to 7% of the control value at 24 h in the kidney. The pretreatment of animals with either actinomycin D or cycloheximide almost completely blocked the Co2+-mediated increase of ODC activity. Co2+ complexed with either cysteine or glutathione (GSH) failed to induce ODC. Depletion of hepatic GSH content by treatment of rats with diethyl maleate greatly enhanced the inducing effect of Co2+ on ODC. The inhibitors of ODC, 1,3-diaminopropane and alpha-difluoromethylornithine, were able to inhibit the induction of the enzyme, without affecting the induction of haem oxygenase by Co2+. Methylglyoxal bis(guanylhydrazone), an inhibitor of S-adenosylmethionine decarboxylase, significantly inhibited the Co2+-mediated induction of both ODC and haem oxygenase. It is suggested that the inducing effects of Co2+ on ODC and haem oxygenase are brought about in a similar manner. PMID:3754136

Radiosensitivity and Induction of Apoptosis by High LET Carbon Ion Beam and Low LET Gamma Radiation: A Comparative Study

PubMed Central

Ghorai, Atanu; Bhattacharyya, Nitai P.; Sarma, Asitikantha; Ghosh, Utpal

2014-01-01

Cancer treatment with high LET heavy ion beam, especially, carbon ion beam (12C), is becoming very popular over conventional radiotherapy like low LET gamma or X-ray. Combination of Poly(ADP-ribose) polymerase (PARP) inhibitor with xenotoxic drugs or conventional radiation (gamma or X-ray) is the newer approach for cancer therapy. The aim of our study was to compare the radiosensitivity and induction of apoptosis by high LET 12C and low LET gamma radiation in HeLa and PARP-1 knocked down cells. We did comet assay to detect DNA breaks, clonogenic survival assay, and cell cycle analysis to measure recovery after DNA damage. We measured apoptotic parameters like nuclear fragmentation and caspase-3 activation. DNA damage, cell killing, and induction of apoptosis were significantly higher for 12C than gamma radiation in HeLa. Cell killing and apoptosis were further elevated upon knocking down of PARP-1. Both 12C and gamma induced G2/M arrest although the 12C had greater effect. Unlike the gamma, 12C irradiation affects DNA replication as detected by S-phase delay in cell cycle analysis. So, we conclude that high LET 12C has greater potential over low LET gamma radiation in killing cells and radiosensitization upon PARP-1 inhibition was several folds greater for 12C than gamma. PMID:25018892

Evaluation of on-line desalter-inductively coupled plasma-mass spectrometry system for determination of Cr(III), Cr(VI), and total chromium concentrations in natural water and urine samples

NASA Astrophysics Data System (ADS)

Sun, Y. C.; Lin, C. Y.; Wu, S. F.; Chung, Y. T.

2006-02-01

We have developed a simple and convenient method for the determination of Cr(III), Cr(VI), and the total chromium concentrations in natural water and urine samples that use a flow injection on-line desalter-inductively coupled plasma-mass spectrometry system. When using aqueous ammonium chloride (pH 8) as the stripping solution, the severe interference from sodium in the matrix can be eliminated prior to inductively coupled plasma-mass spectrometry measurement, and the Cr(VI) level can be determined directly. To determine the total concentration of Cr in natural water and urine samples, we used H 2O 2 or HNO 3 to decompose the organic matter and convert all chromium species into the Cr(VI) oxidation state. To overcome the spectral interference caused by the matrix chloride ion in the resulting solutions, we employed cool plasma to successfully suppress chloride-based molecular ion interference during the inductively coupled plasma-mass spectrometry measurement. By significantly eliminating interference from the cationic and anionic components in the matrices prior to the inductively coupled plasma-mass spectrometry measurement, we found that the detection limit reached 0.18 μg L - 1 (based on 3 sigma). We validated this method through the analysis of the total chromium content in two reference materials (NIST 1643c and 2670E) and through measuring the recovery in spiked samples.

Effects of feedstock availability on the negative ion behavior in a C{sub 4}F{sub 8} inductively coupled plasma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhao, Shu-Xia; Research group PLASMANT, Dept. Chemistry, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp; Gao, Fei

2015-07-21

In this paper, the negative ion behavior in a C{sub 4}F{sub 8} inductively coupled plasma (ICP) is investigated using a hybrid model. The model predicts a non-monotonic variation of the total negative ion density with power at low pressure (10–30 mTorr), and this trend agrees well with experiments that were carried out in many fluorocarbon (fc) ICP sources, like C{sub 2}F{sub 6}, CHF{sub 3}, and C{sub 4}F{sub 8}. This behavior is explained by the availability of feedstock C{sub 4}F{sub 8} gas as a source of the negative ions, as well as by the presence of low energy electrons due tomore » vibrational excitation at low power. The maximum of the negative ion density shifts to low power values upon decreasing pressure, because of the more pronounced depletion of C{sub 4}F{sub 8} molecules, and at high pressure (∼50 mTorr), the anion density continuously increases with power, which is similar to fc CCP sources. Furthermore, the negative ion composition is identified in this paper. Our work demonstrates that for a clear understanding of the negative ion behavior in radio frequency C{sub 4}F{sub 8} plasma sources, one needs to take into account many factors, like the attachment characteristics, the anion composition, the spatial profiles, and the reactor configuration. Finally, a detailed comparison of our simulation results with experiments is conducted.« less

Ion energy spread and current measurements of the rf-driven multicusp ion source

NASA Astrophysics Data System (ADS)

Lee, Y.; Gough, R. A.; Kunkel, W. B.; Leung, K. N.; Perkins, L. T.; Pickard, D. S.; Sun, L.; Vujic, J.; Williams, M. D.; Wutte, D.

1997-03-01

Axial energy spread and useful beam current of positive ion beams have been carried out using a radio frequency (rf)-driven multicusp ion source. Operating the source with a 13.56 MHz induction discharge, the axial energy spread is found to be approximately 3.2 eV. The extractable beam current of the rf-driven source is found to be comparable to that of filament-discharge sources. With a 0.6 mm diameter extraction aperture, a positive hydrogen ion beam current density of 80 mA/cm2 can be obtained at a rf input power of 2.5 kW. The expected source lifetime is much longer than that of filament discharges.

Apparatus for diffusion separation

DOEpatents

Nierenberg, William A.; Pontius, Rex B.

1976-08-10

1. The method of testing the separation efficiency of porous permeable membranes which comprises causing a stream of a gaseous mixture to flow into contact with one face of a finely porous permeable membrane under such conditions that a major fraction of the mixture diffuses through the membrane, maintaining a rectangular cross section of the gaseous stream so flowing past said membrane, continuously recirculating the gas that diffuses through said membrane and continuously withdrawing the gas that does not diffuse through said membrane and maintaining the volume of said recirculating gas constant by continuously introducing into said continuously recirculating gas stream a mass of gas equivalent to that which is continuously withdrawn from said gas stream and comparing the concentrations of the light component in the entering gas, the withdrawn gas and the recirculated gas in order to determine the efficiency of said membrane.

Effect of recirculation rate on methane production and SEBAR system performance using active stage digester.

PubMed

Tubtong, Cheevanuch; Towprayoon, Sirintornthep; Connor, Michael Anthony; Chaiprasert, Pawinee; Nopharatana, Annop

2010-09-01

A project was undertaken to examine the feasibility of treating organic wastes from Thai fruit and vegetable markets using the sequential batch anaerobic digester (SEBAR) approach. A key feature of the SEBAR system is the regular interchanging, or recirculation, of portions of leachate between each freshly filled digester and a support digester to which it is coupled until it is ready to operate independently. Leachate transfer from this support digester to the fresh waste digester provides additional alkalinity to help counteract the effects of early high acid release rates; it also helps build a balanced microbial population in the fresh waste digester. To optimize the leachate recirculation process, the effect of varying the quantities of leachate interchanged between freshly filled waste digesters and the still highly active support digesters to which they were coupled was studied. It was found that increasing the recirculation rate accelerated the onset of both waste degradation and methane production. The increasing of recirculation rate from 10% to 20% and 10% to 30% could reduce the SEBAR cycle period by approximately 7% and 22% without significant reduction in the amount of methane obtained from the systems. The methane yields were 0.0063, 0.0068 and 0.0077 l g(-1) VS added in the NEW digester per day using leachate recirculation rates of 10%, 20% and 30%, respectively. This finding has potentially important practical and economic implications for those using the SEBAR system to add value to market waste.

CFD modeling of hydro-biochemical behavior of MSW subjected to leachate recirculation.

PubMed

Feng, Shi-Jin; Cao, Ben-Yi; Li, An-Zheng; Chen, Hong-Xin; Zheng, Qi-Teng

2018-02-01

The most commonly used method of operating landfills more sustainably is to promote rapid biodegradation and stabilization of municipal solid waste (MSW) by leachate recirculation. The present study is an application of computational fluid dynamics (CFD) to the 3D modeling of leachate recirculation in bioreactor landfills using vertical wells. The objective is to model and investigate the hydrodynamic and biochemical behavior of MSW subject to leachate recirculation. The results indicate that the maximum recirculated leachate volume can be reached when vertical wells are set at the upper middle part of a landfill (H W /H T  = 0.4), and increasing the screen length can be more helpful in enlarging the influence radius than increasing the well length (an increase in H S /H W from 0.4 to 0.6 results in an increase in influence radius from 6.5 to 7.7 m). The time to reach steady state of leachate recirculation decreases with the increase in pressure head; however, the time for leachate to drain away increases with the increase in pressure head. It also showed that methanogenic biomass inoculum of 1.0 kg/m 3 can accelerate the volatile fatty acid depletion and increase the peak depletion rate to 2.7 × 10 -6  kg/m 3 /s. The degradation-induced void change parameter exerts an influence on the processes of MSW biodegradation because a smaller parameter value results in a greater increase in void space.

Radiation-quality dependent cellular response in mutation induction in normal human cells.

PubMed

Suzuki, Masao; Tsuruoka, Chizuru; Uchihori, Yukio; Kitamura, Hisashi; Liu, Cui Hua

2009-09-01

We studied cellular responses in normal human fibroblasts induced with low-dose (rate) or low-fluence irradiations of different radiation types, such as gamma rays, neutrons and high linear energy transfer (LET) heavy ions. The cells were pretreated with low-dose (rate) or low-fluence irradiations (approximately 1 mGy/7-8 h) of 137Cs gamma rays, 241Am-Be neutrons, helium, carbon and iron ions before irradiations with an X-ray challenging dose (1.5 Gy). Helium (LET = 2.3 keV/microm), carbon (LET = 13.3 keV/microm) and iron (LET = 200 keV/microm) ions were produced by the Heavy Ion Medical Accelerator in Chiba (HIMAC), Japan. No difference in cell-killing effect, measured by a colony forming assay, was observed among the pretreatment with different radiation types. In mutation induction, which was detected in the hypoxanthine-guanine phosphoribosyltransferase (hprt) locus to measure 6-thioguanine resistant clones, there was no difference in mutation frequency induced by the X-ray challenging dose between unpretreated and gamma-ray pretreated cells. In the case of the pretreatment of heavy ions, X-ray-induced mutation was around 1.8 times higher in helium-ion pretreated and 4.0 times higher in carbon-ion pretreated cells than in unpretreated cells (X-ray challenging dose alone). However, the mutation frequency in cells pretreated with iron ions was the same level as either unpretreated or gamma-ray pretreated cells. In contrast, it was reduced at 0.15 times in cells pretreated with neutrons when compared to unpretreated cells. The results show that cellular responses caused by the influence of hprt mutation induced in cells pretreated with low-dose-rate or low-fluence irradiations of different radiation types were radiation-quality dependent manner.

Irradiation With Carbon Ion Beams Induces Apoptosis, Autophagy, and Cellular Senescence in a Human Glioma-Derived Cell Line

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jinno-Oue, Atsushi; Shimizu, Nobuaki; 21st Century Center of Excellence Program for Biomedical Research Using Accelerator Technology, Maebashi, Gunma

2010-01-15

Purpose: We examined biological responses of human glioma cells to irradiation with carbon ion beams (C-ions). Methods and Materials: A human glioma-derived cell line, NP-2, was irradiated with C-ions. Apoptotic cell nuclei were stained with Hoechst 33342. Induction of autophagy was examined either by staining cells with monodansylcadaverine (MDC) or by Western blotting to detect conversion of microtuble-associated protein light chain 3 (MAP-LC3) (LC3-I) to the membrane-bound form (LC3-II). Cellular senescence markers including induction of senescence-associated beta-galactosidase (SA-beta-gal) were examined. The mean telomere length of irradiated cells was determined by Southern blot hybridization. Expression of tumor suppressor p53 and cyclin/cyclin-dependentmore » kinase inhibitor p21{sup WAF1/CIP1} in the irradiated cells was analyzed by Western blotting. Results: When NP-2 cells were irradiated with C-ions at 6 Gy, the major population of the cells died of apoptosis and autophagy. The residual fraction of attached cells (<1% of initially irradiated cells) could not form a colony: however, they showed a morphological phenotype consistent with cellular senescence, that is, enlarged and flattened appearance. The senescent nature of these attached cells was further indicated by staining for SA-beta-gal. The mean telomere length was not changed after irradiation with C-ions. Phosphorylation of p53 at serine 15 as well as the expression of p21{sup WAF1/CIP1} was induced in NP-2 cells after irradiation. Furthermore, we found that irradiation with C-ions induced cellular senescence in a human glioma cell line lacking functional p53. Conclusions: Irradiation with C-ions induced apoptosis, autophagy, and cellular senescence in human glioma cells.« less

Computational hydrodynamics and optical performance of inductively-coupled plasma adaptive lenses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mortazavi, M.; Urzay, J., E-mail: jurzay@stanford.edu; Mani, A.

2015-06-15

This study addresses the optical performance of a plasma adaptive lens for aero-optical applications by using both axisymmetric and three-dimensional numerical simulations. Plasma adaptive lenses are based on the effects of free electrons on the phase velocity of incident light, which, in theory, can be used as a phase-conjugation mechanism. A closed cylindrical chamber filled with Argon plasma is used as a model lens into which a beam of light is launched. The plasma is sustained by applying a radio-frequency electric current through a coil that envelops the chamber. Four different operating conditions, ranging from low to high powers andmore » induction frequencies, are employed in the simulations. The numerical simulations reveal complex hydrodynamic phenomena related to buoyant and electromagnetic laminar transport, which generate, respectively, large recirculating cells and wall-normal compression stresses in the form of local stagnation-point flows. In the axisymmetric simulations, the plasma motion is coupled with near-wall axial striations in the electron-density field, some of which propagate in the form of low-frequency traveling disturbances adjacent to vortical quadrupoles that are reminiscent of Taylor-Görtler flow structures in centrifugally unstable flows. Although the refractive-index fields obtained from axisymmetric simulations lead to smooth beam wavefronts, they are found to be unstable to azimuthal disturbances in three of the four three-dimensional cases considered. The azimuthal striations are optically detrimental, since they produce high-order angular aberrations that account for most of the beam wavefront error. A fourth case is computed at high input power and high induction frequency, which displays the best optical properties among all the three-dimensional simulations considered. In particular, the increase in induction frequency prevents local thermalization and leads to an axisymmetric distribution of electrons even after introduction of spatial disturbances. The results highlight the importance of accounting for spatial effects in the numerical computations when optical analyses of plasma lenses are pursued in this range of operating conditions.« less

The efficacy of alfaxalone for immersion anesthesia in koi carp (Cyprinus carpio).

PubMed

Minter, Larry J; Bailey, Kate M; Harms, Craig A; Lewbart, Gregory A; Posner, Lysa P

2014-07-01

To characterize the physiologic and behavioral effects of a single induction dose and two maintenance doses of alfaxalone delivered by water immersion in the anesthesia of koi (Cyprinus carpio). Prospective, within-subject complete crossover design. Six adult koi (Cyprinus carpio) with a median body weight of 344.5 g (range 292.0-405.0 g). Koi were immersed in water containing 10 mg L(-1) alfaxalone until immobile and then maintained with alfaxalone at either 1 or 2.5 mg L(-1) via a recirculating water system. Times for anesthetic induction and recovery periods were recorded. Physiologic and blood gas parameters were evaluated before, during and after the anesthetic trial. Response to noxious stimuli was also assessed. Median anesthesia induction time for all fish was 5.4 minutes. Median recovery time was 11.8 and 26.4 minutes in the 1.0 and 2.5 mg L(-1) doses, respectively, which were significantly different (p = 0.04). Cessation of opercular movement occurred in 0/6 and 4/6 fish exposed to 1.0 and 2.5 mg L(-1) dose respectively. No difference was observed in median heart rate over the duration of the anesthetic events. Response to noxious stimulation was 4/6 and 0/6 in the 1.0 and 2.5 mg L(-1) doses respectively. Oxygenation and ventilation did not change during the experiment, but there was a significant decrease in blood pH along with an increase in blood lactate concentration. Administration of alfaxalone, via water immersion, as an induction and maintenance anesthesia agent provided rapid and reliable anesthesia of koi with no mortality. The maintenance dose of 2.5 mg L(-1) was sufficient to prevent response to noxious stimuli but was associated with a clinically relevant depression in opercular rate. © 2014 Association of Veterinary Anaesthetists and the American College of Veterinary Anesthesia and Analgesia.

Removal of hexavalent chromium from wastewater using PPy/Fe3O4 magnetic nanocomposite influenced by rotating magnetic field from two pole three-phase induction motor

NASA Astrophysics Data System (ADS)

Aigbe, U. O.; Ho, W. H.; Maity, A.; Khenfouch, M.; Srinivasu, V.

2018-03-01

The influence of varying rotating magnetic field using a 2-pole three-phase induction motor on the removal of hexavalent chromium ions from wastewater using polypyrrole magnetic nanocomposite was explored in this study. Hexavalent chromium removal in this study was observed to be pH dependent under the influence of rotating magnetic field, as the percentage removal of hexavalent chromium decreased with increase in pH. The percentage amount of hexavalent chromium ions removed from the aqueous solution increased as the rotating magnetic field intensity was increased from 8.96-12.15 mT in the anticlockwise direction and 10.10-13.38 mT in the clockwise direction with maximum removals of 73% and 81% observed.

The effects of the pulsatile period on the size of recirculation bubble in the vicinity of stent struts

NASA Astrophysics Data System (ADS)

Jiang, B.; Thondapu, V.; Barlis, P.; Poon, E. K. W.; Ooi, A. S. H.

2017-04-01

Incomplete stent apposition (ISA) is sometimes found in stent deployment at complex lesions, and it is considered to be one of the causes of post-stenting complications, such as late stent thrombosis and restenosis. The presence of ISA leads to large recirculation bubbles behind the stent struts, which can reduce shear stress at the arterial wall that retards neointimal formation process and thus lead to complications. Computational fluid dynamics (CFD) simulations are performed on simplified two-dimensional axisymmetric arterial models with stents struts of square and circular cross-sectional shapes at a malapposition distance of 120 μm from the arterial wall. To investigate the effects of pulsatile flow period on the dynamics of the recirculation bubbles, high fidelity simulations are carried out with pulsatile flows of period 0.4 s and 0.8 s. Under the condition of the same flow rate, both square and circular strut cases show that shorter period provides greater flow deceleration, leading to the formation of a larger recirculation bubble. With the same thickness, circular strut has a significant improvement over the square strut in terms of the size of the recirculation bubble, and therefore less likely to lead to complications.

Correlation between Reynolds number and eccentricity effect in stenosed artery models.

PubMed

Javadzadegan, Ashkan; Shimizu, Yasutomo; Behnia, Masud; Ohta, Makoto

2013-01-01

Flow recirculation and shear strain are physiological processes within coronary arteries which are associated with pathogenic biological pathways. Distinct Quite apart from coronary stenosis severity, lesion eccentricity can cause flow recirculation and affect shear strain levels within human coronary arteries. The aim of this study is to analyse the effect of lesion eccentricity on the transient flow behaviour in a model of a coronary artery and also to investigate the correlation between Reynolds number (Re) and the eccentricity effect on flow behaviour. A transient particle image velocimetry (PIV) experiment was implemented in two silicone based models with 70% diameter stenosis, one with eccentric stenosis and one with concentric stenosis. At different times throughout the flow cycle, the eccentric model was always associated with a greater recirculation zone length, maximum shear strain rate and maximum axial velocity; however, the highest and lowest impacts of eccentricity were on the recirculation zone length and maximum shear strain rate, respectively. Analysis of the results revealed a negative correlation between the Reynolds number (Re) and the eccentricity effect on maximum axial velocity, maximum shear strain rate and recirculation zone length. As Re number increases the eccentricity effect on the flow behavior becomes negligible.

The benefits of flue gas recirculation in waste incineration.

PubMed

Liuzzo, Giuseppe; Verdone, Nicola; Bravi, Marco

2007-01-01

Flue gas recirculation in the incinerator combustion chamber is an operative technique that offers substantial benefits in managing waste incineration. The advantages that can be obtained are both economic and environmental and are determined by the low flow rate of fumes actually emitted if compared to the flue gas released when recirculation is not conducted. Simulations of two incineration processes, with and without flue gas recirculation, have been carried out by using a commercial flowsheeting simulator. The results of the simulations demonstrate that, from an economic point of view, the proposed technique permits a greater level of energy recovery (up to +3%) and, at the same time, lower investment costs as far as the equipment and machinery constituting the air pollution control section of the plant are concerned. At equal treatment system efficiencies, the environmental benefits stem from the decrease in the emission of atmospheric pollutants. Throughout the paper reference is made to the EC legislation in the field of environmental protection, thus ensuring the general validity in the EU of the foundations laid and conclusions drawn henceforth. A numerical example concerning mercury emission quantifies the reported considerations and illustrates that flue gas recirculation reduces emission of this pollutant by 50%.

Effects of aeration and leachate recirculation on methyl mercaptan emissions from landfill.

PubMed

Zhang, Siyuan; Long, Yuyang; Fang, Yuan; Du, Yao; Liu, Weijia; Shen, Dongsheng

2017-10-01

The issue of odorous volatile organic sulfur compound methyl mercaptan (MM) released from landfill sites cannot be ignored for its extremely low odor threshold and high toxicity. In this study, we focused on the formation and emission of MM in four lab-scaled simulated landfill reactors running in different operation modes, namely, R1 and R2, without leachate recirculation, running under anaerobic and semi-aerobic atmosphere, R3 and R4, with leachate recirculation, running under anaerobic and semi-aerobic atmosphere, respectively. From the perspective of odor abatement, the semi-aerobic operation mode can efficiently lower the emitted MM concentration by 87.4-94.9%, relative to the semi-aerobic operation mode. Furthermore, under semi-aerobic conditions, leachate recirculation substantially shortened the period of MM influence by 12.7%, thus reducing the risk of affecting the surrounding atmospheric environment. The formation of MM was dependent on the characteristics such as the volatile fatty acid concentration and chemical oxygen demand in the leachate and sulfide concentration of the refuse. Overall, MM release can be effectively controlled with semi-aerobic operation mode and leachate recirculation. Copyright © 2017 Elsevier Ltd. All rights reserved.

An innovative sewage sludge reduction by using a combined mesophilic anaerobic and thermophilic aerobic process with thermal-alkaline treatment and sludge recirculation.

PubMed

Cho, Hyun Uk; Park, Sang Kyu; Ha, Jeong Hyub; Park, Jong Moon

2013-11-15

Lab-scale High Efficiency Digestion (HED) systems containing a Mesophilic Anaerobic Reactor (MAR), Thermophilic Aerobic Reactor (TAR), liquid/solid separation unit, and thermal-alkaline treatment were developed to evaluate the efficiencies of sludge reduction and methane production. The HED process was divided into three phases to examine the influence of sludge pretreatment and pretreated sludge recirculation using TCOD and VSS reduction, COD solubilization, and methane production. The VSS removal with a solid/liquid separation unit, sludge recirculation, and thermal-alkaline treatment drastically increased up to 95% compared to the feed concentration. In addition, the results of COD solubilization and VSS/TSS showed that the solubilization of cells and organic matters by the thermal-alkaline treatment was highly increased, which was also consistent with the SEM images. In particular, the methane production rate increased 24-fold when the feed sludge and recirculated sludge were pretreated together. Collectively, the HED experiments performed with sludge recirculation and thermal-alkaline treatment demonstrated that the HED systems can be successfully employed for highly efficient sewage sludge reduction and methane gas production. Copyright © 2013 Elsevier Ltd. All rights reserved.

The effect of flow recirculation on abdominal aortic aneurysm

NASA Astrophysics Data System (ADS)

Taib, Ishkrizat; Amirnordin, Shahrin Hisham; Madon, Rais Hanizam; Mustafa, Norrizal; Osman, Kahar

2012-06-01

The presences of flow recirculation at the abdominal aortic aneurysm (AAA) region yield the unpredictable failure of aneurismal wall. The failure of the aneurismal wall is closely related to the hemodynamic factor. Hemodynamic factor such as pressure and velocity distribution play a significance role of aneurysm growth and rupture. By using the computational approach, the influence of hemodynamic factor is investigated using computational fluid dynamic (CFD) method on the virtual AAA model. The virtual 3D AAAs model was reconstructed from Spiral Computed Tomography scan (CT-scan). The blood flow is assumed as being transient, laminar and Newtonian within a rigid section of the vessel. The blood flow also driven by an imposed of pressure gradient in the form of physiological waveform. The pulsating blood flow is also considered in this simulation. The results on pressure distribution and velocity profile are analyzed to interpret the behaviour of flow recirculation. The results show the forming of vortices is seen at the aneurysm bulge. This vortices is form at the aneurysm region then destroyed rapidly by flow recirculation. Flow recirculation is point out much higher at distal end of aneurysm closed to iliac bifurcation. This phenomenon is managed to increase the possibility of aneurysm growth and rupture.

Induction of apoptosis by accelerated heavy-ion beams in cultured fetal rat testes and its modification

NASA Astrophysics Data System (ADS)

Wang, Bing; Tanaka, Kaoru; Shang, Yi; Fujita, Kazuko; Ninomiya, Yasuharu; Moreno, Stephanie G.; Coffigny, Herve; Hayata, Isamu; Murakami, Masahiro; Eguchi-Kasai, Kiyomi; Nenoi, Mitsuru

The increasing human activities in space missions make the study on effects from high-LET ionizing radiation an important issue to be addressed. We reported previously that prenatal irradiations with heavy-ion beams on gestation day 15 generally induced markedly detrimental effects on prenatal gonads, postnatal testicular development and male breeding activity in rats. To explore the mechanisms involved in radiation-induced gonocyte apoptosis in fetal gonads, which played a critical role in the fate of postnatal testis development, accelerated heavy-ion irradiations and organotypic culture of Wistar fetal rat testes were applied to investigations focused on cellular and molecular events after irradiations with or without chemical addition. Results showed that, in addition to the clustered distribution, both the time course and the percentage of apoptosis in gonocytes on gestation day 15 equivalent in vitro appeared similar to that in utero after exposure to either carbon-ion beams with a LET value of about 13 keV/µm or neon-ion beams with a LET value of about 30 keV/µm. Irradiations induced increased p53 expression in a dose dependent manner and decreased expressions of p21 and Bcl- 2 by Western Blot examination. Administration of pan-caspase inhibitor prior to irradiations effectively inhibited apoptosis occurrence and reduced the extent of clustered apoptosis, while such effects were not observed with the presence of p53 inhibitor, gap junction inhibitor, or nitric oxide specific scavenger. These findings indicated that irradiations of cultured fetal rat testes manifested pathologically similar apoptosis induction in gonocytes to that in utero. P53 expression was possibly responsible for the response to radiation damage rather than induction of apoptosis. The syncytial organization of gonocytes played a key role in formation of the clustered apoptosis, an event that both gap junction inhibitor and nitric oxide specific scavenger were incapable of preventing.

Jovian Plasmas Torus Interaction with Europa. Plasma Wake Structure and Effect of Inductive Magnetic Field: 3D Hybrid Kinetic Simulation

NASA Technical Reports Server (NTRS)

Lipatov, A. S.; Cooper, J F.; Paterson, W. R.; Sittler, E. C., Jr.; Hartle, R. E.; Simpson, David G.

2013-01-01

The hybrid kinetic model supports comprehensive simulation of the interaction between different spatial and energetic elements of the Europa moon-magnetosphere system with respect to a variable upstream magnetic field and flux or density distributions of plasma and energetic ions, electrons, and neutral atoms. This capability is critical for improving the interpretation of the existing Europa flyby measurements from the Galileo Orbiter mission, and for planning flyby and orbital measurements (including the surface and atmospheric compositions) for future missions. The simulations are based on recent models of the atmosphere of Europa (Cassidy et al., 2007; Shematovich et al., 2005). In contrast to previous approaches with MHD simulations, the hybrid model allows us to fully take into account the finite gyroradius effect and electron pressure, and to correctly estimate the ion velocity distribution and the fluxes along the magnetic field (assuming an initial Maxwellian velocity distribution for upstream background ions). Photoionization, electron-impact ionization, charge exchange and collisions between the ions and neutrals are also included in our model. We consider the models with Oþ þ and Sþ þ background plasma, and various betas for background ions and electrons, and pickup electrons. The majority of O2 atmosphere is thermal with an extended non-thermal population (Cassidy et al., 2007). In this paper, we discuss two tasks: (1) the plasma wake structure dependence on the parameters of the upstream plasma and Europa's atmosphere (model I, cases (a) and (b) with a homogeneous Jovian magnetosphere field, an inductive magnetic dipole and high oceanic shell conductivity); and (2) estimation of the possible effect of an induced magnetic field arising from oceanic shell conductivity. This effect was estimated based on the difference between the observed and modeled magnetic fields (model II, case (c) with an inhomogeneous Jovian magnetosphere field, an inductive magnetic dipole and low oceanic shell conductivity).

Contribution of the backstreaming ions to the Self-Magnetic pinch (SMP) diode current

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mazarakis, Michael G.; Cuneo, Michael E.; Fournier, Sean D.

2016-08-08

Summary form only given. The results presented here were obtained with an SMP diode mounted at the front high voltage end of the RITS accelerator. RITS is a Self-Magnetically Insulated Transmission Line (MITL) voltage adder that adds the voltage pulses of six 1.3 MV inductively insulated cavities. Our experiments had two objectives: first to measure the contribution of the back-streaming ion currents emitted from the anode target to the diode beam current, and second to try to evaluate the energy of those ions and hence the actual Anode-Cathode (A-K) gap actual voltage. In any very high voltage inductive voltage addermore » (IVA) utilizing MITLs to transmit the power to the diode load, the precise knowledge of the accelerating voltage applied on the anode-cathode (A-K) gap is problematic. The accelerating voltage quoted in the literature is from estimates based on measurements of the anode and cathode currents of the MITL far upstream from the diode and utilizing the para-potential flow theories and inductive corrections. Thus it would be interesting to have another independent measurement to evaluate the A-K voltage. The diode's anode is made of a number of high Z metals in order to produce copious and energetic flash x-rays. The backstreaming currents are a strong fraction of the anode materials and their stage of cleanness and gas adsorption. We have measured the back-streaming ion currents emitted from the anode and propagating through a hollow cathode tip for various diode configurations and different techniques of target cleaning treatments, such as heating to very high temperatures with DC and pulsed current, with RF plasma cleaning and with both plasma cleaning and heating. Finally, we have also evaluated the A-K gap voltage by ion filtering techniques.« less

Mixer assembly for a gas turbine engine having a pilot mixer with a corner flame stabilizing recirculation zone

NASA Technical Reports Server (NTRS)

Dai, Zhongtao (Inventor); Cohen, Jeffrey M. (Inventor); Fotache, Catalin G. (Inventor)

2012-01-01

A mixer assembly for a gas turbine engine is provided, including a main mixer, and a pilot mixer having an annular housing in which a corner is formed between an aft portion of the housing and a bulkhead wall in which a corner recirculation zone is located to stabilize and anchor the flame of the pilot mixer. The pilot mixer can further include features to cool the annular housing, including in the area of the corner recirculation zone.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhao, Shu-Xia; Zhang, Yu-Ru; Research Group PLASMANT, Department of Chemistry, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp

A hybrid model is used to investigate the fragmentation of C{sub 4}F{sub 8} inductive discharges. Indeed, the resulting reactive species are crucial for the optimization of the Si-based etching process, since they determine the mechanisms of fluorination, polymerization, and sputtering. In this paper, we present the dissociation degree, the density ratio of F vs. C{sub x}F{sub y} (i.e., fluorocarbon (fc) neutrals), the neutral vs. positive ion density ratio, details on the neutral and ion components, and fractions of various fc neutrals (or ions) in the total fc neutral (or ion) density in a C{sub 4}F{sub 8} inductively coupled plasma source,more » as well as the effect of pressure and power on these results. To analyze the fragmentation behavior, the electron density and temperature and electron energy probability function (EEPF) are investigated. Moreover, the main electron-impact generation sources for all considered neutrals and ions are determined from the complicated C{sub 4}F{sub 8} reaction set used in the model. The C{sub 4}F{sub 8} plasma fragmentation is explained, taking into account many factors, such as the EEPF characteristics, the dominance of primary and secondary processes, and the thresholds of dissociation and ionization. The simulation results are compared with experiments from literature, and reasonable agreement is obtained. Some discrepancies are observed, which can probably be attributed to the simplified polymer surface kinetics assumed in the model.« less

Visualization of complex DNA damage along accelerated ions tracks

NASA Astrophysics Data System (ADS)

Kulikova, Elena; Boreyko, Alla; Bulanova, Tatiana; Ježková, Lucie; Zadneprianetc, Mariia; Smirnova, Elena

2018-04-01

The most deleterious DNA lesions induced by ionizing radiation are clustered DNA double-strand breaks (DSB). Clustered or complex DNA damage is a combination of a few simple lesions (single-strand breaks, base damage etc.) within one or two DNA helix turns. It is known that yield of complex DNA lesions increases with increasing linear energy transfer (LET) of radiation. For investigation of the induction and repair of complex DNA lesions, human fibroblasts were irradiated with high-LET 15N ions (LET = 183.3 keV/μm, E = 13MeV/n) and low-LET 60Co γ-rays (LET ≈ 0.3 keV/μm) radiation. DNA DSBs (γH2AX and 53BP1) and base damage (OGG1) markers were visualized by immunofluorecence staining and high-resolution microscopy. The obtained results showed slower repair kinetics of induced DSBs in cells irradiated with accelerated ions compared to 60Co γ-rays, indicating induction of more complex DNA damage. Confirming previous assumptions, detailed 3D analysis of γH2AX/53BP1 foci in 15N ions tracks revealed more complicated structure of the foci in contrast to γ-rays. It was shown that proteins 53BP1 and OGG1 involved in repair of DNA DSBs and modified bases, respectively, were colocalized in tracks of 15N ions and thus represented clustered DNA DSBs.

Matrix effects in inductively coupled plasma mass spectrometry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Xiaoshan

1995-07-07

The inductively coupled plasma is an electrodeless discharge in a gas (usually Ar) at atmospheric pressure. Radio frequency energy generated by a RF power source is inductively coupled to the plasma gas through a water cooled load coil. In ICP-MS the "Fassel" TAX quartz torch commonly used in emission is mounted horizontally. The sample aerosol is introduced into the central flow, where the gas kinetic temperature is about 5000 K. The aerosol is vaporized, atomized, excited and ionized in the plasma, and the ions are subsequently extracted through two metal apertures (sampler and skimmer) into the mass spectrometer. In ICP-MS,more » the matrix effects, or non-spectroscopic interferences, can be defined as the type of interferences caused by dissolved concomitant salt ions in the solution. Matrix effects can be divided into two categories: (1) signal drift due to the deposition of solids on the sampling apertures; and/or (2) signal suppression or enhancement by the presence of the dissolved salts. The first category is now reasonably understood. The dissolved salts, especially refractory oxides, tend to deposit on the cool tip of the sampling cone. The clogging of the orifices reduces the ion flow into the ICP-MS, lowers the pressure in the first stage of ICP-MS, and enhances the level of metal oxide ions. Because the extent of the clogging increases with the time, the signal drifts down. Even at the very early stage of the development of ICP-MS, matrix effects had been observed. Houk et al. found out that the ICP-MS was not tolerant to solutions containing significant amounts of dissolved solids.« less

Preparation and analysis of standardized waste samples for Controlled Ecological Life Support Systems (CELSS)

NASA Technical Reports Server (NTRS)

Carden, J. L.; Browner, R.

1982-01-01

The preparation and analysis of standardized waste samples for controlled ecological life support systems (CELSS) are considered. Analysis of samples from wet oxidation experiments, the development of ion chromatographic techniques utilizing conventional high pressure liquid chromatography (HPLC) equipment, and an investigation of techniques for interfacing an ion chromatograph (IC) with an inductively coupled plasma optical emission spectrometer (ICPOES) are discussed.

Asymmetric Ion-Pairing Catalysis

PubMed Central

Brak, Katrien

2014-01-01

Charged intermediates and reagents are ubiquitous in organic transformations. The interaction of these ionic species with chiral neutral, anionic, or cationic small molecules has emerged as a powerful strategy for catalytic, enantioselective synthesis. This review describes developments in the burgeoning field of asymmetric ion-pairing catalysis with an emphasis on the insights that have been gleaned into the structural and mechanistic features that contribute to high asymmetric induction. PMID:23192886

The Light Ion Pulsed Power Induction Accelerator for ETF

DTIC Science & Technology

1995-07-01

the technical development necessary to demonstrate scientific and engineering feasibility for fusion energy production with a reprated driver. In...order for ETF to be cost effective, the accelerator system must be able to drive several target chambers which will test various Inertial Fusion ... Energy (IFE) reactor technologies. We envision an elevator system positioning and removing multiple target chambers from the center area of the ion beam

Mass cytometry: technique for real time single cell multitarget immunoassay based on inductively coupled plasma time-of-flight mass spectrometry.

PubMed

Bandura, Dmitry R; Baranov, Vladimir I; Ornatsky, Olga I; Antonov, Alexei; Kinach, Robert; Lou, Xudong; Pavlov, Serguei; Vorobiev, Sergey; Dick, John E; Tanner, Scott D

2009-08-15

A novel instrument for real time analysis of individual biological cells or other microparticles is described. The instrument is based on inductively coupled plasma time-of-flight mass spectrometry and comprises a three-aperture plasma-vacuum interface, a dc quadrupole turning optics for decoupling ions from neutral components, an rf quadrupole ion guide discriminating against low-mass dominant plasma ions, a point-to-parallel focusing dc quadrupole doublet, an orthogonal acceleration reflectron analyzer, a discrete dynode fast ion detector, and an 8-bit 1 GHz digitizer. A high spectrum generation frequency of 76.8 kHz provides capability for collecting multiple spectra from each particle-induced transient ion cloud, typically of 200-300 micros duration. It is shown that the transients can be resolved and characterized individually at a peak frequency of 1100 particles per second. Design considerations and optimization data are presented. The figures of merit of the instrument are measured under standard inductively coupled plasma (ICP) operating conditions (<3% cerium oxide ratio). At mass resolution (full width at half-maximum) M/DeltaM > 900 for m/z = 159, the sensitivity with a standard sample introduction system of >1.4 x 10(8) ion counts per second per mg L(-1) of Tb and an abundance sensitivity of (6 x 10(-4))-(1.4 x 10(-3)) (trailing and leading masses, respectively) are shown. The mass range (m/z = 125-215) and abundance sensitivity are sufficient for elemental immunoassay with up to 60 distinct available elemental tags. When <15 elemental tags are used, a higher sensitivity mode at lower resolution (M/DeltaM > 500) can be used, which provides >2.4 x 10(8) cps per mg L(-1) of Tb, at (1.5 x 10(-3))-(5.0 x 10(-3)) abundance sensitivity. The real-time simultaneous detection of multiple isotopes from individual 1.8 microm polystyrene beads labeled with lanthanides is shown. A real time single cell 20 antigen expression assay of model cell lines and leukemia patient samples immuno-labeled with lanthanide-tagged antibodies is presented.

Effect of self recirculation casing treatment on the performance of a turbocharger centrifugal compressor

NASA Astrophysics Data System (ADS)

Gancedo, Matthieu

Increase in emission regulations in the transport industry brings the need to have more efficient engines. A path followed by the automobile industry is to downsize the size of the internal combustion engine and increase the air density at the intake to keep the engine power when needed. Typically a centrifugal compressor is used to force the air into the engine, it can be powered from the engine shaft (superchargers) or extracting energy contained into the hot exhaust gases with a turbine (turbochargers). The flow range of the compressor needs to match the one of the engine. However compressors mass flow operating range is limited by choke on the high end and surge on the low end. In order to extend the operation at low mass flow rates, the use of passive devices for turbocharger centrifugal compressors was explored since the late 80's. Hence, casing treatments including flow recirculation from the inducer part of the compressor have been shown to move the surge limit to lower flows. Yet, the working mechanisms are still not well understood and thus, to optimize the design of this by-pass system, it is necessary to determine the nature of the changes induced by the device both on the dynamic stability of the pressure delivery and on the flow at the inlet. The compressor studied here features a self-recirculating casing treatment at the inlet. The recirculation passage could be blocked to carry a direct comparison between the cases with and without the flow feature. To grasp the effect on compressor stability, pressure measurements were taken in the different constituting elements of the compressor. The study of the mean pressure variations across the operating map showed that the tongue region is a limiting element. Dynamic pressure measurements revealed that the instabilities generated near the inducer when the recirculation is blocked increase the overall instability levels at the compressor outlet and propagating pressure waves starting at the tongue occurred, different in nature from rotating stall. The flow velocity was also measured at the inlet of the compressor by means of planar PIV measurements. The case without recirculation showed strong back flow occurrence at low MFR on the shroud of the inlet passage due to tip recirculation. With recirculation, this back flow was significantly reduced improving the overall stability. However, with the current recirculation channels design, there is an efficiency penalty and the recirculated flow introduces non-homogeneities in the mixing region. Finally, to explore experimentally the effect of variations of the casing treatment, several different designs were tested. It was seen that modifications of the supporting rib shape impacted the efficiency. Also, improvements on the surge line were obtained with flow reinjection near the inducer in the direction of the main flow at low speeds and with induced counter swirl for all speeds.

Impact of nitrate-enhanced leachate recirculation on gaseous releases from a landfill bioreactor cell

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tallec, G.; Bureau, C.; Peu, P.

2009-07-15

This study evaluates the impact of nitrate injection on a full scale landfill bioreactor through the monitoring of gaseous releases and particularly N{sub 2}O emissions. During several weeks, we monitored gas concentrations in the landfill gas collection system as well as surface gas releases with a series of seven static chambers. These devices were directly connected to a gas chromatograph coupled to a flame ionisation detector and an electron capture detector (GC-FID/ECD) placed directly on the field. Measurements were performed before, during and after recirculation of raw leachate and nitrate-enhanced leachate. Raw leachate recirculation did not have a significant effectmore » on the biogas concentrations (CO{sub 2}, CH{sub 4} and N{sub 2}O) in the gas extraction network. However, nitrate-enhanced leachate recirculation induced a marked increase of the N{sub 2}O concentrations in the gas collected from the recirculation trench (100-fold increase from 0.2 ppm to 23 ppm). In the common gas collection system however, this N{sub 2}O increase was no more detectable because of dilution by gas coming from other cells or ambient air intrusion. Surface releases through the temporary cover were characterized by a large spatial and temporal variability. One automated chamber gave limited standard errors over each experimental period for N{sub 2}O releases: 8.1 {+-} 0.16 mg m{sup -2} d{sup -1} (n = 384), 4.2 {+-} 0.14 mg m{sup -2} d{sup -1} (n = 132) and 1.9 {+-} 0.10 mg m{sup -2} d{sup -1} (n = 49), during, after raw leachate and nitrate-enhanced leachate recirculation, respectively. No clear correlation between N{sub 2}O gaseous surface releases and recirculation events were evidenced. Estimated N{sub 2}O fluxes remained in the lower range of what is reported in the literature for landfill covers, even after nitrate injection.« less

Groundwater-driven nutrient inputs to coastal lagoons: The relevance of lagoon water recirculation as a conveyor of dissolved nutrients.

PubMed

Rodellas, Valentí; Stieglitz, Thomas C; Andrisoa, Aladin; Cook, Peter G; Raimbault, Patrick; Tamborski, Joseph J; van Beek, Pieter; Radakovitch, Olivier

2018-06-16

Evaluating the sources of nutrient inputs to coastal lagoons is required to understand the functioning of these ecosystems and their vulnerability to eutrophication. Whereas terrestrial groundwater processes are increasingly recognized as relevant sources of nutrients to coastal lagoons, there are still limited studies evaluating separately nutrient fluxes driven by terrestrial groundwater discharge and lagoon water recirculation through sediments. In this study, we assess the relative significance of these sources in conveying dissolved inorganic nutrients (NO 3 - , NH 4 + and PO 4 3- ) to a coastal lagoon (La Palme lagoon; France, Mediterranean Sea) using concurrent water and radon mass balances. The recirculation of lagoon water through sediments represents a source of NH 4 + (1900-5500 mol d -1 ) and PO 4 3- (22-71 mol d -1 ), but acts as a sink of NO 3 - . Estimated karstic groundwater-driven inputs of NO 3 - , NH 4 + and PO 4 3- to the lagoon are on the order of 200-1200, 1-12 and 1.5-8.7 mol d -1 , respectively. A comparison between the main nutrient sources to the lagoon (karstic groundwater, recirculation, diffusion from sediments, inputs from a sewage treatment plant and atmospheric deposition) reveals that the recirculation of lagoon water through sediments is the main source of both dissolved inorganic nitrogen (DIN) and phosphorous (DIP) to La Palme lagoon. These results are in contrast with several studies conducted in systems influenced by terrestrial groundwater inputs, where groundwater is often assumed to be the main pathway for dissolved inorganic nutrient loads. This work highlights the important role of lagoon water recirculation through permeable sediments as a major conveyor of dissolved nutrients to coastal lagoons and, thus, the need for a sound understanding of the recirculation-driven nutrient fluxes and their ecological implications to sustainably manage lagoonal ecosystems. Copyright © 2018. Published by Elsevier B.V.

A recirculating stream aquarium for ecological studies.

Treesearch

Gordon H. Reeves; Fred H. Everest; Carl E. McLemore

1983-01-01

Investigations of the ecological behavior of fishes often require studies in both natural and artificial stream environments. We describe a large, recirculating stream aquarium and its controls, constructed for ecological studies at the Forestry Sciences Laboratory in Corvallis.

Multi-Point Interferometric Rayleigh Scattering using Dual-Pass Light Recirculation

NASA Technical Reports Server (NTRS)

Bivolaru, Daniel; Danehy, Paul M.; Cutler, Andrew D.

2008-01-01

This paper describes for the first time an interferometric Rayleigh scattering system using dual-pass light recirculation (IRS-LR) capable of simultaneously measuring at multiple points two orthogonal components of flow velocity in combustion flows using single shot laser probing. An additional optical path containing the interferometer input mirror, a quarter-wave plate, a polarization dependent beam combiner, and a high reflectivity mirror partially recirculates the light that is rejected by the interferometer. Temporally- and spatially-resolved acquisitions of Rayleigh spectra in a large-scale combustion-heated supersonic axi-symmetric jet were performed to demonstrate the technique. Recirculating of Rayleigh scattered light increases the number of photons analyzed by the system up to a factor of 1.8 compared with previous configurations. This is equivalent to performing measurements with less laser energy or performing measurements with the previous system in gas flows at higher temperatures.

Recurrent amoebic gill infestation in rainbow trout cultured in a semiclosed water recirculation system

USGS Publications Warehouse

Noble, A.C.; Herman, R.L.; Noga, E.J.; Bullock, G.L.

1997-01-01

Five lots of commercially purchased juvenile rainbow trout Oncorhynchus mykiss (17-44 g) stocked in a continuous-production water recirculation system became infested with gilt amoebae. The amoebae were introduced into the recirculation system, as evidenced by their presence on gills of fish held in quarantine tanks. Based on their morphology, as seen in histological sections and by electron microscopy, the amoebae appeared to be more closely related to the family Cochliopodiidae than to other taxa of free living amoebae. Attempts to culture the amoebae in different media, at different temperatures of incubation, and in fish cell culture were not successful. Initial treatment of the recirculation system with formalin at 167 parts per million (ppm) for 1 h eliminated amoebae from the gills. Subsequent treatments of the entire system with formalin at 50-167 ppm reduced the intensity of further infestations.

Increasing EDV Range through Intelligent Cabin Air Handling Strategies: Annual Progress Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leighton, Daniel; Rugh, John

Computational fluid dynamics (CFD) simulations of a Ford Focus Electric demonstrated that a split flow heating, ventilating and air conditioning (HVAC) system with rear recirculation ducts can reduce cabin heating loads by up to 57.4% relative to full fresh air usage under some conditions (steady state, four passengers, ambient temperature of -5 deg C). Simulations also showed that implementing a continuous recirculation fraction control system into the original equipment manufacturer (OEM) HVAC system can reduce cabin heating loads by up to 50.0% relative to full fresh air usage under some conditions (steady state, four passengers, ambient temperature of -5 degmore » C). Identified that continuous fractional recirculation control of the OEM system can provide significant energy savings for EVs at minimal additional cost, while a split flow HVAC system with rear recirculation ducts only provides minimal additional improvement at significant additional cost.« less

Investigation of hydrocarbon oil transformation by gliding arc discharge: comparison of batch and recirculated configurations

NASA Astrophysics Data System (ADS)

Whitehead, J. Christopher; Prantsidou, Maria

2016-04-01

The degradation of liquid dodecane was studied in a gliding arc discharge (GAD) of humid argon or nitrogen. A batch or recirculating configuration was used. The products in the gaseous and liquid phase were analysed by infrared and chromatography and optical emission spectroscopy was used to identify the excited species in the discharge. The best degradation performance comes from the use of humid N2 but a GAD of humid argon produces fewer gas-phase products but more liquid-phase end-products. A wide range of products such as heavier saturated or unsaturated hydrocarbons both aliphatic and aromatic, and oxidation products mainly alcohols, but also aldehydes, ketones and esters are produced in the liquid-phase. The recirculating treatment mode is more effective than the batch mode increasing the reactivity and changing the product selectivities. Overall, the study shows promising results for the organic liquid waste treatment, especially in the recirculating mode.

Cryogenic studies for the proposed CERN large hadron electron collider (LHEC)

NASA Astrophysics Data System (ADS)

Haug, F.; LHeC Study Team, The

2012-06-01

The LHeC (Large Hadron electron Collider) is a proposed future colliding beam facility for lepton-nucleon scattering particle physics at CERN. A new 60 GeV electron accelerator will be added to the existing 27 km circumference 7 TeV LHC for collisions of electrons with protons and heavy ions. Two basic design options are being pursued. The first is a circular accelerator housed in the existing LHC tunnel which is referred to as the "Ring-Ring" version. Low field normal conducting magnets guide the particle beam while superconducting (SC) RF cavities cooled to 2 K are installed at two opposite locations at the LHC tunnel to accelerate the beams. For this version in addition a 10 GeV re-circulating SC injector will be installed. In total four refrigerators with cooling capacities between 1.2 kW and 3 kW @ 4.5 K are needed. The second option, referred to as the "Linac-Ring" version consists of a race-track re-circulating energyrecovery type machine with two 1 km long straight acceleration sections. The 944 high field 2 K SC cavities dissipate 30 kW at CW operation. Eight 10 kW @ 4.5 K refrigerators are proposed. The particle detector contains a combined SC solenoid and dipole forming the cold mass and an independent liquid argon calorimeter. Cooling is done with two individual small sized cryoplants; a 4.5 K helium, and a 87 K liquid nitrogen plant.

Encapsulated cell bioremediation: Evaluation on the basis of particle tracer tests

DOE Office of Scientific and Technical Information (OSTI.GOV)

Petrich, C.R.; Stormo, K.E.; Ralston, D.R.

1998-09-01

Microencapsulation of degradative organisms enhances microorganism survivability. The use of encapsulated cell microbeads for in situ biodegradation depends not only on microorganism survival but also on microbead transport characteristics. Two forced-gradient, recirculating-loop tracer experiments were conducted to evaluate the feasibility of encapsulated cell transport and bioremediation on the basis of polystyrene microsphere transport results. The tracer tests were conducted in a shallow, confined, unconsolidated, heterogeneous, sedimentary aquifer using bromide ion and 2 {micro}m, 5 {micro}m, and 15{micro}m microsphere tracers. Significant differences were observed in the transport of bromide solute and polystyrene microspheres. Microspheres reached peak concentrations in monitoring wells beforemore » bromide, which was thought to reflect the influence of aquifer heterogeneity. Greater decreases in microsphere C/C{sub 0} ratios were observed with distance from the injection wells than in bromide C/C{sub 0} ratios, which was attributed to particle filtration and/or settling. Several methods might be considered for introducing encapsulated cell microbeads into a subsurface environment, including direct injection into a contaminated aquifer zone, injection through a recirculating ground water flow system, or emplacement in a subsurface microbial curtain in advance of a plume. However, the in situ use of encapsulated cells in an aquifer is probably limited to aquifers containing sufficiently large pore spaces, allowing passage of at least some encapsulated cells. The use of encapsulated cells may also be limited by differences in solute and microbead transport patterns and flowpath clogging by larger encapsulated cell microbeads.« less

Weak low-frequency electromagnetic oscillations in water.

PubMed

Liboff, A R; Poggi, Claudio; Pratesi, Piero

2017-01-01

Recent observations of low-frequency electromagnetic oscillations in water suggest an inductive structural component. Accordingly, we assume a helical basis enabling us to model water as an LC tuned oscillator. A proposed tetrahedral structure consisting of three water molecules and one hydronium ion is incorporated into the Boerdijk-Coxeter tetrahelix to form long water chains that are shown to have resonance frequencies consistent with observation. This model also serves to explain separately reported claims of ion cyclotron resonance of hydronium ions, in that the tetrahelix provides a built-in path for helical proton-hopping.

Kinetic studies of adsorption of Cu (II) from aqueous solution by coriander seeds (Coriandrum Sativum)

NASA Astrophysics Data System (ADS)

Kadiri, L.; Lebkiri, A.; Rifi, E. H.; Ouass, A.; Essaadaoui, Y.; Lebkiri, I.; Hamad, H.

2018-05-01

The adsorption of copper ions Cu2+ by Coriandrum Sativum seeds (CSS) from aqueous solution was studied in order to highlight the importance of coriander seeds as a potential tool in the treatment of wastewaters containing heavy metals. The kinetic studies of adsorption of Cu (II) were discussed using the spectroscopic technique "Inducting Coupled Plasma" (ICP). The effects of initial copper ion concentration and contact time were determined. All results show that coriander seeds have, over their culinary and medicinal benefits, a significant adsorbent power of copper ions.

Final report for DOE Grant No. DE-SC0006609 - Persistence of Microbially Facilitated Calcite Precipitation as an in situ Treatment for Strontium-90

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, Robert W.; Fujita, Yoshiko; Hubbard, Susan S.

2013-11-15

Subsurface radionuclide and metal contaminants throughout the U.S. Department of Energy (DOE) complex pose one of DOE's greatest challenges for long-term stewardship. One promising stabilization mechanism for divalent ions, such as the short-lived radionuclide 90Sr, is co-precipitation in calcite. We have previously found that nutrient addition can stimulate microbial ureolytic activity, that this activity accelerates calcite precipitation and co-precipitation of Sr, and that higher calcite precipitation rates can result in increased Sr partitioning. We have conducted integrated field, laboratory, and computational research to evaluate the relationships between ureolysis and calcite precipitation rates and trace metal partitioning under environmentally relevant conditions,more » and investigated the coupling between flow/flux manipulations and precipitate distribution. A field experimental campaign conducted at the Integrated Field Research Challenge (IFRC) site located at Rifle, CO was based on a continuous recirculation design; water extracted from a down-gradient well was amended with urea and molasses (a carbon and electron donor) and re-injected into an up-gradient well. The goal of the recirculation design and simultaneous injection of urea and molasses was to uniformly accelerate the hydrolysis of urea and calcite precipitation over the entire inter-wellbore zone. The urea-molasses recirculation phase lasted, with brief interruptions for geophysical surveys, for 12 days and was followed by long-term monitoring which continued for 13 months. A post experiment core located within the inter-wellbore zone was collected on day 321 and characterized with respect to cation exchange capacity, mineral carbonate content, urease activity, ureC gene abundance, extractable ammonium (a urea hydrolysis product) content, and the 13C isotopic composition of solid carbonates. It was also subjected to selective extractions for strontium and uranium. Result of the core characterization suggest that urea hydrolysis occurred primarily within the upper portion of the inter-wellbore zone and that strontium was mobilized from cation exchange sites and subsequently co-precipitated with new calcium carbonate.« less

The sodium exosphere and magnetosphere of Mercury

NASA Astrophysics Data System (ADS)

Ip, W.-H.

1986-05-01

Following the recent optical discovery of intense sodium D-line emission from Mercury, the scenario of an extended exosphere of sodium and other metallic atoms is explored. It is shown that the strong effect of solar radiation pressure acceleration would permit the escape of Na atoms from Mercury's surface even if they are ejected at a velocity lower than the surface escape velocity. Fast photoionization of the Na atoms is effective in limiting the tailward extension of the sodium exosphere, however. The subsequent loss of the photoions to the magnetosphere could be a significant source of the magnetospheric plasma. The recirculation of the magnetospheric charged particles to the planetary surface could also play an important role in maintaining an extended sodium exosphere as well as a magnetosphere of sputtered metallic ions.

A Reconstruction of Subtropical Western North Pacific SST Variability Back to 1578, Based on a Porites Coral Sr/Ca Record from the Northern Ryukyus, Japan

NASA Astrophysics Data System (ADS)

Kawakubo, Y.; Alibert, C.; Yokoyama, Y.

2017-12-01

We present a seasonal reconstruction of sea surface temperature (SST) from 1578 to 2008, based on a Porites coral Sr/Ca record from the northern Ryukyus, within the Kuroshio southern recirculation gyre. Interannual SST anomalies are generally 0.5°C, making Sr/Ca-derived SST reconstructions a challenging task. Replicate measurements along adjacent coral growth axes, enabled by the laser ablation inductively coupled plasma mass spectrometry technique used here, give evidence of rather large uncertainties. Nonetheless, derived winter SST anomalies are significantly correlated with the Western Pacific atmospheric pattern which has a dominant influence on winter temperature in East Asia. Annual mean SSTs show interdecadal variations, notably cold intervals between 1670 and 1700 during the Maunder Minimum (MM) and between 1766 and 1788 characterized by a negative phase of the North Atlantic Oscillation. Cold summers in 1783 and 1784 coincide with the long-lasting Laki eruption that had a profound impact on the Northern Hemisphere climate, including the severe "Tenmei" famine in Japan. The decades between 1855 and 1900 are significantly cooler than the first half of the twentieth century, while those between 1700 and 1765, following the MM, are warmer than average. SST variability in the Ryukyus is only marginally influenced by the Pacific Decadal Oscillation, so that external forcing remains the main driver of low-frequency temperature changes. However, the close connection between the Kuroshio extension (KE) and its recirculation gyre suggests that decadal SST anomalies associated with the KE front also impact the Ryukyus, and there is a possible additional role for feedback of the Kuroshio-Oyashio variability to the large-scale atmosphere at decadal timescale.

Role of Hot Water System Design on Factors Influential to Pathogen Regrowth: Temperature, Chlorine Residual, Hydrogen Evolution, and Sediment

PubMed Central

Brazeau, Randi H.; Edwards, Marc A.

2013-01-01

Abstract Residential water heating is linked to growth of pathogens in premise plumbing, which is the primary source of waterborne disease in the United States. Temperature and disinfectant residual are critical factors controlling increased concentration of pathogens, but understanding of how each factor varies in different water heater configurations is lacking. A direct comparative study of electric water heater systems was conducted to evaluate temporal variations in temperature and water quality parameters including dissolved oxygen levels, hydrogen evolution, total and soluble metal concentrations, and disinfectant decay. Recirculation tanks had much greater volumes of water at temperature ranges with potential for increased pathogen growth when set at 49°C compared with standard tank systems without recirculation. In contrast, when set at the higher end of acceptable ranges (i.e., 60°C), this relationship was reversed and recirculation systems had less volume of water at risk for pathogen growth compared with conventional systems. Recirculation tanks also tended to have much lower levels of disinfectant residual (standard systems had 40–600% higher residual), 4–6 times as much hydrogen, and 3–20 times more sediment compared with standard tanks without recirculation. On demand tankless systems had very small volumes of water at risk and relatively high levels of disinfectant residual. Recirculation systems may have distinct advantages in controlling pathogens via thermal disinfection if set at 60°C, but these systems have lower levels of disinfectant residual and greater volumes at risk if set at lower temperatures. PMID:24170969

Removal of viable bioaerosol particles with a low-efficiency HVAC filter enhanced by continuous emission of unipolar air ions.

PubMed

Huang, R; Agranovski, I; Pyankov, O; Grinshpun, S

2008-04-01

Continuous emission of unipolar ions has been shown to improve the performance of respirators and stationary filters challenged with non-biological particles. In this study, we investigated the ion-induced enhancement effect while challenging a low-efficiency heating, ventilation and air-conditioning (HVAC) filter with viable bacterial cells, bacterial and fungal spores, and viruses. The aerosol concentration was measured in real time. Samples were also collected with a bioaerosol sampler for viable microbial analysis. The removal efficiency of the filter was determined, respectively, with and without an ion emitter. The ionization was found to significantly enhance the filter efficiency in removing viable biological particles from the airflow. For example, when challenged with viable bacteria, the filter efficiency increased as much as four- to fivefold. For viable fungal spores, the ion-induced enhancement improved the efficiency by a factor of approximately 2. When testing with virus-carrying liquid droplets, the original removal efficiency provided by the filter was rather low: 9.09 +/- 4.84%. While the ion emission increased collection about fourfold, the efficiency did not reach 75-100% observed with bacteria and fungi. These findings, together with our previously published results for non-biological particles, demonstrate the feasibility of a new approach for reducing aerosol particles in HVAC systems used for indoor air quality control. Recirculated air in HVAC systems used for indoor air quality control in buildings often contains considerable number of viable bioaerosol particles because of limited efficiency of the filters installed in these systems. In the present study, we investigated - using aerosolized bacterial cells, bacterial and fungal spores, and virus-carrying particles - a novel idea of enhancing the performance of a low-efficiency HVAC filter utilizing continuous emission of unipolar ions in the filter vicinity. The findings described in this paper, together with our previously published results for non-biological particles, demonstrate the feasibility of the newly developed approach.

Ion acceleration in a helicon source due to the self-bias effect

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wiebold, Matt; Sung, Yung-Ta; Scharer, John E.

2012-05-15

Time-averaged plasma potential differences up to 165 V over several hundred Debye lengths are observed in low pressure (p{sub n} < 1 mTorr) expanding argon plasmas in the Madison Helicon eXperiment (MadHeX). The potential gradient leads to ion acceleration greater than that predicted by ambipolar expansion, exceeding E{sub i} Almost-Equal-To 7 kT{sub e} in some cases. RF power up to 500 W at 13.56 MHz is supplied to a half-turn, double-helix antenna in the presence of a nozzle magnetic field, adjustable up to 1 kG. A retarding potential analyzer (RPA) measures the ion energy distribution function (IEDF) and a sweptmore » emissive probe measures the plasma potential. Single and double probes measure the electron density and temperature. Two distinct mode hops, the capacitive-inductive (E-H) and inductive-helicon (H-W) transitions, are identified by jumps in density as RF power is increased. In the capacitive (E) mode, large fluctuations of the plasma potential (V{sub p-p} Greater-Than-Or-Equivalent-To 140V, V{sub p-p}/V{sub p} Almost-Equal-To 150%) exist at the RF frequency and its harmonics. The more mobile electrons can easily respond to RF-timescale gradients in the plasma potential whereas the inertially constrained ions cannot, leading to an initial flux imbalance and formation of a self-bias voltage between the source and expansion chambers. In the capacitive mode, the ion acceleration is not well described by an ambipolar relation, while in the inductive and helicon modes the ion acceleration more closely follows an ambipolar relation. The scaling of the potential gradient with the argon flow rate and RF power are investigated, with the largest potential gradients observed for the lowest flow rates in the capacitive mode. The magnitude of the self-bias voltage agrees with that predicted for RF self-bias at a wall. Rapid fluctuations in the plasma potential result in a time-dependent axial electron flux that acts to 'neutralize' the accelerated ion population, resulting in a zero net time-averaged current through the acceleration region when an insulating upstream boundary condition is enforced. Grounding the upstream endplate increases the self-bias voltage compared to a floating endplate.« less

Full-scale demonstration of in situ cometabolic biodegradation of trichloroethylene in groundwater 1. Dynamics of a recirculating well system

NASA Astrophysics Data System (ADS)

Gandhi, Rahul K.; Hopkins, Gary D.; Goltz, Mark N.; Gorelick, Steven M.; McCarty, Perry L.

2002-04-01

Recirculating well systems provide an engine for the in situ treatment of subsurface contaminants. Although numerous recirculating wells have been installed in the field, for such systems, there is a paucity of comprehensive monitoring data and models constrained to data appearing in the research literature. Here we present an extensive data set combined with detailed inverse and simulation analyses for a two-well groundwater recirculation system used for in situ bioremediation at Edwards Air Force Base in southern California. The ``conveyor belt'' flow system, which was established for in situ treatment of trichloroethylene (TCE) in two bioactive zones, was created by pumping water upward in one well and downward in another well, each well being screened in both the upper and lower aquifers. A bromide tracer test was conducted and extensively monitored for 60 days. Combined inverse analysis was conducted on hydraulic heads from 38 monitoring wells, 32 bromide concentration histories, and a constraint on the degree of recirculation that was based on TCE concentration data. Four different formulations involving alternative weighting schemes used in a nonlinear weighted least squares simulation-regression analysis were explored. The best formulation provided parameter estimates with tight bounds on estimated covariances, suggesting that the model provides a reasonable description of the hydrogeologic system. Our investigation indicates the geometry of the recirculation zone and the degree of recirculation under two different sets of operating conditions. Surprisingly, our analysis suggests that the effects of aquifer heterogeneity are not significant at this site under the conditions of forced recirculation. Furthermore, anomalous flow through an open monitoring well created significant vertical short-circuiting between the generally insulated aquifers. Flow through this small open conduit was equivalent to as much as 33% of the flow through the pumping wells. Using the model as a guide, we treated the aquifer system and bioactive zones as an equivalent mixed reactor to develop simple expressions relating effluent concentrations to influent concentrations. We demonstrate how these expressions are useful in predicting the removal of TCE that had undergone in situ bioremediation in the recirculatory treatment well system. The finite element model developed in this work serves as the foundation for a reactive transport simulator that we developed to analyze bioremediation which occurred during a 444 day experiment [Gandhi et al., 2002].

Neutralized ion beam modification of cellulose membranes for study of ion charge effect on ion-beam-induced DNA transfer

NASA Astrophysics Data System (ADS)

Prakrajang, K.; Sangwijit, K.; Anuntalabhochai, S.; Wanichapichart, P.; Yu, L. D.

2012-02-01

Low-energy ion beam biotechnology (IBBT) has recently been rapidly developed worldwide. Ion-beam-induced DNA transfer is one of the important applications of IBBT. However, mechanisms involved in this application are not yet well understood. In this study plasma-neutralized ion beam was applied to investigate ion charge effect on induction of DNA transfer. Argon ion beam at 7.5 keV was neutralized by RF-driven plasma in the beam path and then bombarded cellulose membranes which were used as the mimetic plant cell envelope. Electrical properties such as impedance and capacitance of the membranes were measured after the bombardment. An in vitro experiment on plasmid DNA transfer through the cellulose membrane was followed up. The results showed that the ion charge input played an important role in the impedance and capacitance changes which would affect DNA transfer. Generally speaking, neutral particle beam bombardment of biologic cells was more effective in inducing DNA transfer than charged ion beam bombardment.

A dipole-assisted solid-phase extraction microchip combined with inductively coupled plasma-mass spectrometry for online determination of trace heavy metals in natural water.

PubMed

Shih, Tsung-Ting; Hsu, I-Hsiang; Chen, Shun-Niang; Chen, Ping-Hung; Deng, Ming-Jay; Chen, Yu; Lin, Yang-Wei; Sun, Yuh-Chang

2015-01-21

We employed a polymeric material, poly(methyl methacrylate) (PMMA), for fabricating a microdevice and then implanted the chlorine (Cl)-containing solid-phase extraction (SPE) functionality into the PMMA chip to develop an innovative on-chip dipole-assisted SPE technique. Instead of the ion-ion interactions utilized in on-chip SPE techniques, the dipole-ion interactions between the highly electronegative C-Cl moieties in the channel interior and the positively charged metal ions were employed to facilitate the on-chip SPE procedures. Furthermore, to avoid labor-intensive manual manipulation, a programmable valve manifold was designed as an interface combining the dipole-assisted SPE microchip and inductively coupled plasma-mass spectrometry (ICP-MS) to achieve the fully automated operation. Under the optimized operation conditions for the established system, the detection limits for each analyte ion were obtained based on three times the standard deviation of seven measurements of the blank eluent solution. The limits ranged from 3.48 to 20.68 ng L(-1), suggesting that this technique appears uniquely suited for determining the levels of heavy metal ions in natural water. Indeed, a series of validation procedures demonstrated that the developed method could be satisfactorily applied to the determination of trace heavy metals in natural water. Remarkably, the developed device was durable enough to be reused more than 160 times without any loss in its analytical performance. To the best of our knowledge, this is the first study reporting on the combination of a dipole-assisted SPE microchip and elemental analysis instrument for the online determination of trace heavy metal ions.

Low-energy N-ion beam biotechnology application in the induction of Thai jasmine rice mutant with improved seed storability

NASA Astrophysics Data System (ADS)

Semsang, Nuananong; Techarang, Jiranat; Yu, Liangdeng; Phanchaisri, Boonrak

2018-06-01

Low-energy heavy-ion beam is a novel biotechnology used for mutation induction in plants. We used a low-energy N-ion beam to induce mutations in Thai jasmine rice (Oryza sativa L. cv. KDML 105) to improve the yield and seed quality. Seeds of BKOS6, a Thai jasmine rice mutant previously induced by ion beams, were re-bombarded with 60-kV-accelerated N-ions (N++N2+) to fluences of 1-2 × 1016 ions/cm2. The resulting mutant, named HyKOS21, exhibited photoperiod insensitivity, semi-dwarfness, and high yield potential. Seed storability of the mutant was studied in natural and accelerated ageing conditions and compared to that of KDML 105 and six other Thai rice varieties. In both testing conditions, HyKOS21 mutant had the highest seed storability among the tested varieties. After storage in the natural condition for 18 months, HyKOS21 had a seed germination percentage nearly two times as that of the original KDML 105. Biochemical analysis showed that the lipid peroxidation level of the mutant seeds was the lowest among those of the tested varieties. Furthermore, an expression analysis of genes encoding lipoxygenase isoenzyme (lox1, lox2, and lox3) revealed that the mutant lacked expression of lox1 and lox2 and expressed only lox3 in seeds. These results may explain the improved seed longevity of the mutant after storage. This work provides further evidence of the modification of biological materials using a low-energy ion beam to produce rice mutants with improved yield and seed storability. The benefits of this technology, to create new varieties with improved values, could serve for local economic development.

High LET radiation shows no major cellular and functional effects on primary cardiomyocytes in vitro

NASA Astrophysics Data System (ADS)

Heselich, Anja; Frieß, Johannes L.; Ritter, Sylvia; Benz, Naja P.; Layer, Paul G.; Thielemann, Christiane

2018-02-01

It is well known that ionizing radiation causes adverse effects on various mammalian tissues. However, there is little information on the biological effects of heavy ion radiation on the heart. In order to fill this gap, we systematically examined DNA-damage induction and repair, as well as proliferation and apoptosis in avian cardiomyocyte cultures irradiated with heavy ions such as titanium and iron, relevant for manned space-flight, and carbon ions, as used for radiotherapy. Further, and to our knowledge for the first time, we analyzed the effect of heavy ion radiation on the electrophysiology of primary cardiomyocytes derived from chicken embryos using the non-invasive microelectrode array (MEA) technology. As electrophysiological endpoints beat rate and field action potential duration were analyzed. The cultures clearly exhibited the capacity to repair induced DNA damage almost completely within 24 h, even at doses of 7 Gy, and almost completely recovered from radiation-induced changes in proliferative behavior. Interestingly, no significant effects on apoptosis could be detected. Especially the functionality of primary cardiac cells exhibited a surprisingly high robustness against heavy ion radiation, even at doses of up to 7 Gy. In contrast to our previous study with X-rays the beat rate remained more or less unaffected after heavy ion radiation, independently of beam quality. The only change we could observe was an increase of the field action potential duration of up to 30% after titanium irradiation, diminishing within the following three days. This potentially pathological observation may be an indication that heavy ion irradiation at high doses could bear a long-term risk for cardiovascular disease induction.

Experimental evaluation of analyte excitation mechanisms in the inductively coupled plasma

NASA Astrophysics Data System (ADS)

Lehn, Scott A.; Hieftje, Gary M.

2003-10-01

The inductively coupled plasma (ICP) is a justifiably popular source for atomic emission spectrometry. However, despite its popularity, the ICP is still only partially understood. Even the mechanisms of analyte excitation remain unclear; some energy levels are quite clearly populated by charge transfer while others might be populated by electron-ion recombination, by electron impact, or by Penning processes. Distinguishing among these alternatives is possible by means of a steady-state kinetics approach that examines correlations between the emission of a selected atom, ion, or level and the local number densities of species assumed to produce the excitation. In an earlier investigation, strong correlations were found between either calcium atom or ion emission and selected combinations of calcium atom or ion number densities and electron number densities in the plasma. However, all radially resolved data employed in the earlier study were produced from Abel inversion and from measurements that were crude by today's standards. Now, by means of tomographic imaging, laser-saturated atomic fluorescence, and Thomson and Rayleigh scattering, it is possible to measure the required radially resolved data without Abel inversion and with far greater fidelity. The correlations previously studied for calcium have been investigated with these more reliable data. Ion-electron recombination, either radiative or with argon as a third body, was determined to be the most likely excitation mechanism for calcium atom, while electron impact appeared to be the most important process to produce excite-state calcium ions. These results were consistent with the previous study. However, the present study suggests that collisional deactivation, rather than radiative decay, is the most likely mode of returning both calcium atoms and ions to the ground state.

The effect of track structure on the induction of chromosomal aberrations in murine cells

NASA Technical Reports Server (NTRS)

Durante, M.; Cella, L.; Furusawa, Y.; George, K.; Gialanella, G.; Grossi, G.; Pugliese, M.; Saito, M.; Yang, T. C.

1998-01-01

PURPOSE: To measure chromosome aberrations in C3H 10T1/2 mouse fibroblasts using FISH painting at the first mitosis following exposure to 30 keV/microm hydrogen or neon ions. MATERIALS AND METHODS: Cells in plateau-phase were irradiated with 0.86 MeV protons at the TTT-3 Tandem accelerator in Naples (Italy), or with 400 MeV/n Ne ions at the HIMAC accelerator in Chiba (Japan). Colcemid-blocked cells were harvested at the first mitosis following exposure, and chromosome spreads were hybridized in situ with a fluorescein-labelled composite mouse DNA probe specific for chromosomes 2 and 8. RESULTS: Protons were more efficient than neon ions at the same LET in the induction of chromosome interchanges and breaks. Yields of complex exchanges were similar for both particles at the same dose, but protons produced mostly insertions, while with Ne exposure non-reciprocal exchanges were the most frequent complex-type exchange. CONCLUSIONS: Charged particles with the same LET produce different yields of chromosome aberrations, and some observed differences can be explained based on the available track-structure models.

The effect of track structure on the induction of chromosomal aberrations in murine cells.

PubMed

Durante, M; Cella, L; Furusawa, Y; George, K; Gialanella, G; Grossi, G; Pugliese, M; Saito, M; Yang, T C

1998-03-01

To measure chromosome aberrations in C3H 10T1/2 mouse fibroblasts using FISH painting at the first mitosis following exposure to 30 keV/microm hydrogen or neon ions. Cells in plateau-phase were irradiated with 0.86 MeV protons at the TTT-3 Tandem accelerator in Naples (Italy), or with 400 MeV/n Ne ions at the HIMAC accelerator in Chiba (Japan). Colcemid-blocked cells were harvested at the first mitosis following exposure, and chromosome spreads were hybridized in situ with a fluorescein-labelled composite mouse DNA probe specific for chromosomes 2 and 8. Protons were more efficient than neon ions at the same LET in the induction of chromosome interchanges and breaks. Yields of complex exchanges were similar for both particles at the same dose, but protons produced mostly insertions, while with Ne exposure non-reciprocal exchanges were the most frequent complex-type exchange. Charged particles with the same LET produce different yields of chromosome aberrations, and some observed differences can be explained based on the available track-structure models.

Self-terminated etching of GaN with a high selectivity over AlGaN under inductively coupled Cl2/N2/O2 plasma with a low-energy ion bombardment

NASA Astrophysics Data System (ADS)

Zhong, Yaozong; Zhou, Yu; Gao, Hongwei; Dai, Shujun; He, Junlei; Feng, Meixin; Sun, Qian; Zhang, Jijun; Zhao, Yanfei; DingSun, An; Yang, Hui

2017-10-01

Etching of GaN/AlGaN heterostructure by O-containing inductively coupled Cl2/N2 plasma with a low-energy ion bombardment can be self-terminated at the surface of the AlGaN layer. The estimated etching rates of GaN and AlGaN were 42 and 0.6 nm/min, respectively, giving a selective etching ratio of 70:1. To study the mechanism of the etching self-termination, detailed characterization and analyses were carried out, including X-ray photoelectron spectroscopy (XPS) and time-of-flight secondary ion mass spectroscopy (TOF-SIMS). It was found that in the presence of oxygen, the top surface of the AlGaN layer was converted into a thin film of (Al,Ga)Ox with a high bonding energy, which effectively prevented the underlying atoms from a further etching, resulting in a nearly self-terminated etching. This technique enables a uniform and reproducible fabrication process for enhancement-mode high electron mobility transistors with a p-GaN gate.

A hybrid model of biased inductively coupled discharges1

NASA Astrophysics Data System (ADS)

Wen, Deqi; Lieberman, Michael A.; Zhang, Quanzhi; Liu, Yongxin; Wang, Younian

2016-09-01

A hybrid model, i.e. a global model coupled bidirectionally with a parallel Monte-Carlo collision (MCC) sheath model, is developed to investigate an inductively coupled discharge with a bias source. To validate this model, both bulk plasma density and ion energy distribution functions (IEDFs) are compared with experimental measurements in an argon discharge, and a good agreement is obtained. On this basis, the model is extended to weakly electronegative Ar/O2 plasma. The ion energy and angular distribution functions versus bias voltage amplitude are examined. The different ion species (Ar+, O2+,O+) have various behaviors because of the different masses. A low bias voltage, Ar+ has a single energy peak distribution and O+ has a bimodal distribution. At high bias voltage, the energy peak separation of O+ is wider than Ar+. 1This work has been supported by the National Nature Science Foundation of China (Grant No. 11335004) and Specific project (Grant No 2011X02403-001) and partially supported by Department of Energy Office of Fusion Energy Science Contract DE-SC000193 and a gift from the Lam Research Corporation.

Quantitative interpretation of heavy ion effects: Comparison of different systems and endpoints

NASA Astrophysics Data System (ADS)

Kiefer, J.

For a quantitative interpretation of biological heavy ion action the following parameters have to be taken into account: variations of energy depositions in microscopical sites, the dependence of primary lesion formation on local energy density and changes in repairability. They can be studied in objects of different size and with different sensitivities. Results on survival and mutation induction in yeast and in mammalian cells will be compared with theoretical predictions. It is shown that shouldered survival curves of diploid yeast can be adequately described if the final slope is adjusted according to the varying production of primary lesions. This is not the case for mammalian cells where the experiments show a rapid loss of the shoulder with LET, contrary to theoretical expectations. This behaviour is interpreted to mean that the repairability of heavy ion lesions is different in the two systems. Mutation induction is theoretically expected to decrease with higher LET. This is found in yeast but not in mammalian cells where it actually increases. These results suggest a higher rate of misrepair in mammalian cells.

Ion Chromatography as an Alternative to Standard Methods for Analysis of Macro-nutrients in Mehlich 1 Extracts of Unfertilized Forest Soils

Treesearch

Joseph B. Fischer; James H. Miller

2004-01-01

This study evaluates ion chromatography (IC) as an alternative to atomic absorption (AA) and inductively-coupled plasma spectromctry (ICP) for analysis of potassium (K), magnesium (Mg), and calcium (Ca), and and as an alternative to antimonylmolybdate colorimetry and ICP for analysis of phosphorus (P) macro-nutrients in Mehlich 1 extracts. Soils typical of pine forests...

Better Management Practices for Recirculating Aquaculture Systems

USDA-ARS?s Scientific Manuscript database

Under the 2004 federal aquaculture effluent limitation guidelines (Federal Register 2004), recirculating aquaculture systems with an annual production exceeding 45,454 kg (100,000 pounds) are classified as concentrated aquatic animal production (CAAP) facilities and are required to obtain a National...

Production of cobia in recirculating systems

USDA-ARS?s Scientific Manuscript database

Only limited information exists with respect to rearing juvenile cobia Rachycentron canadum to stocker and marketable sizes using recirculating aquaculture systems (RAS). To investigate this topic, two rearing trials were conducted using commercial scale RAS. In Trial 1, juvenile cobia (29 g) we...

Freshwater Institute: Focused on improving recirculating aquaculture system technology

USDA-ARS?s Scientific Manuscript database

Recirculating aquaculture system (RAS) technologies help to overcome barriers to domestic aquaculture expansion and enhance the sustainability of the modern fish farming industry through reduction in environmental impacts. With RAS, fish farm expansion is no longer highly constrained by competition ...

Influence of natural organic matter on the adsorption of metal ion onto clay particles

USGS Publications Warehouse

Schmitt, D.; Taylor, Howard E.; Aiken, G.R.; Roth, D.A.; Frimmel, F.H.

2002-01-01

The influence of natural organic matter (NOM) on the adsorption of Al, Fe, Zn, and Pb onto clay minerals was investigated. Adsorption experiments were carried out at pH = 5 and pH = 7 in the presence and absence of NOM. In general, the presence of NOM decreased the adsorption of metal ions onto the clay particles. Al and Fe were strongly influenced by NOM, whereas Zn and Pb adsorption was only slightly altered. The interaction of the metal ions with the minerals and the influence of NOM on this interaction was investigated by coupling SdFFF with an inductively coupled plasma mass spectrometer (ICPMS) or an inductively coupled plasma atomic emission spectrometer (ICPAES). Quantitative atomization of the clay particles in the ICP was confirmed by comparing elemental content determined by direct injection of the clay into the ICPMS with values from acid digestion. Particle sizes of the clays were found to be between 0.1 and 1 μm by sedimentation field-flow fractionation (SdFFF) with UV detection. Aggregation of particles due to metal adsorption was observed using SdFFF-ICPMS measurements. This aggregation was dependent on the specific metal ion and decreased in the presence of NOM and at higher pH value.

The effect of leachate recirculation with enzyme cellulase addition on waste stability in landfill bioreactor

NASA Astrophysics Data System (ADS)

Saffira, N.; Kristanto, G. A.

2018-01-01

Landfill bioreactor with leachate recirculation is known to enhance waste stabilization. However, the composition of waste in Indonesia is comprised by organic waste which is lignocellulosic materials that considered take a long time to degrade under anaerobic condition. To accelerate the degradation process, enzyme addition is ought to do. Cellulase is an enzyme that can catalyse cellulose and other polysaccharide decomposition processes. Therefore, operation of waste degradation using leachate recirculation with a cellulase addition to enhance waste stabilization was investigated using anaerobic bioreactor landfill. The experiment was performed on 2 conditions; leachate recirculation with cellulase addition and recirculation only as a control. The addition of cellulase is reported to be significant in decreasing organic content, represented by volatile solid parameter. The volatile solid reduction in the cellulase augmented reactor and control reactor was 17.86% and 7.90%, respectively. Cellulase addition also resulted in the highest cellulose reduction. Settlement of the landfill in a bioreactor with enzyme addition (32.67%) was reported to be higher than the control (19.33%). Stabilization of landfill review by the decreasing rate constant of the cellulose and lignin ratio parameter was more rapidly achieved by the enzyme addition (0.014 day-1) compared to control (0.002 day-1).

In Situ Biotreatment of TBA with Recirculation/Oxygenation

PubMed Central

North, Katharine P.; Mackay, Douglas M.; Kayne, Julian S.; Petersen, Daniel; Rasa, Ehsan; Rastegarzadeh, Laleh; Holland, Reef B.; Scow, Kate M.

2012-01-01

The potential for in situ biodegradation of tert-butyl alcohol (TBA) by creation of aerobic conditions in the subsurface with recirculating well pairs was investigated in two field studies conducted at Vandenberg Air Force Base (VAFB). In the first experiment, a single recirculating well pair with bromide tracer and oxygen amendment successfully delivered oxygen to the subsurface for 42 days. TBA concentrations were reduced from approximately 500 μg/L to below the detection limit within the treatment zone and the treated water was detected in a monitoring transect several meters downgradient. In the second experiment, a site-calibrated model was used to design a double recirculating well pair with oxygen amendment, which successfully delivered oxygen to the subsurface for 291 days and also decreased TBA concentrations to below the detection limit. Methylibium petroleiphilum strain PM1, a known TBA-degrading bacterium, was detectable at the study site but addition of oxygen had little impact on the already low baseline population densities, suggesting that there was not enough carbon within the groundwater plume to support significant new growth in the PM1 population. Given favorable hydrogeologic and geochemical conditions, the use of recirculating well pairs to introduce dissolved oxygen into the subsurface is a viable method to stimulate in situ biodegradation of TBA or other aerobically-degradable aquifer contaminants. PMID:23358537

Low NO.sub.x multistage combustor

DOEpatents

Becker, Frederick E.; Breault, Ronald W.; Litka, Anthony F.; McClaine, Andrew W.; Shukla, Kailash

2000-01-01

A high efficiency, Vortex Inertial Staged Air (VIStA) combustor provides ultra-low NO.sub.X production of about 20 ppmvd or less with CO emissions of less than 50 ppmvd, both at 3% O.sub.2. Prompt NO.sub.X production is reduced by partially reforming the fuel in a first combustion stage to CO and H.sub.2. This is achieved in the first stage by operating with a fuel rich mixture, and by recirculating partially oxidized combustion products, with control over stoichiometry, recirculation rate and residence time. Thermal NO.sub.X production is reduced in the first stage by reducing the occurrence of high temperature combustion gas regions. This is achieved by providing the first stage burner with a thoroughly pre-mixed fuel/oxidant composition, and by recirculating part of the combustion products to further mix the gases and provide a more uniform temperature in the first stage. In a second stage combustor thermal NO.sub.X production is controlled by inducing a large flow of flue gas recirculation in the second stage combustion zone to minimize the ultimate temperature of the flame. One or both of the first and second stage burners can be cooled to further reduce the combustion temperature and to improve the recirculation efficiency. Both of these factors tend to reduce production of NO.sub.X.

Thermophysical fundamentals of cyclonic recirculating heating devices

NASA Astrophysics Data System (ADS)

Karpov, S. V.; Zagoskin, A. A.

2017-10-01

This report presents the results of experimental and theoretical research of aerodynamics and convective heat transfer in cyclone devices with the new system of external recirculation of heating gas under the influence of radial pressure gradient in a heat carrier’s swirling turbulent flow. The dynamic problem of tangential velocity distribution in a clearance volume is solved at various re-circulation ratio values including limiting quantities (kr = 0; 1) and variations in cyclonic combustion chamber’s design parameters and operating conditions (Rer); the integrated calculation ratios for fundamental aerodynamic characteristics of a recirculation device are derived. The first experimental and numerical studies of convective heat transfer on internal and external surfaces of a hollow shaft in a swirling recirculation flow are derived through the instrumentality of OpenFOAM, these studies are also conducted for a setting of several cylindrical solid inserts. The external surface heat problem of a hollow cylindrical insert is solved with integral and digital methods; generalized similarity equations for the internal and external surfaces extended in range of Reynolds number are derived. The experimental data is in reasonable agreement with the derived curves and the results of mathematic modelling of convective heat transfer. Calculation recommendations for optimal selection of kr values at various ratios of their geometric characteristics and products utilization rate are obtained.

Pilot-scale study of powdered activated carbon recirculation for micropollutant removal.

PubMed

Meinel, F; Sperlich, A; Jekel, M

Adsorption onto powdered activated carbon (PAC) is a promising technique for the removal of organic micropollutants (OMPs) from treated wastewater. To enhance the adsorption efficiency, PAC is recycled back into the adsorption stage. This technique was examined in pilot scale in comparison to a reference without recirculation. Coagulation with Fe(3+) was carried out simultaneously to adsorption. Extensive OMP measurements showed that recirculation significantly increased OMP eliminations. Thus, significant PAC savings were feasible. The PAC concentration in the contact reactor proved to be an important operating parameter that can be surrogated by the easily measurable total suspended solids (TSS) concentration. OMP eliminations increased with increasing TSS concentrations. At 20 mg PAC L(-1) and 2.8 g TSS L(-1) in the contact reactor, well-adsorbable carbamazepine was eliminated by 97%, moderately adsorbable diclofenac was eliminated by 92% and poorly-adsorbable acesulfame was eliminated by 54% in comparison to 49%, 35% and 18%, respectively, without recirculation. The recirculation system represents an efficient technique, as the PAC's adsorption capacity is practically completely used. Small PAC dosages yield high OMP eliminations. Poorly-adsorbable gabapentin was eliminated to an unexpectedly high degree. A laboratory-scale biomass inhibition study showed that aerobic biodegradation removed gabapentin in addition to adsorption.

In Situ Biotreatment of TBA with Recirculation/Oxygenation.

PubMed

North, Katharine P; Mackay, Douglas M; Kayne, Julian S; Petersen, Daniel; Rasa, Ehsan; Rastegarzadeh, Laleh; Holland, Reef B; Scow, Kate M

2012-01-01

The potential for in situ biodegradation of tert-butyl alcohol (TBA) by creation of aerobic conditions in the subsurface with recirculating well pairs was investigated in two field studies conducted at Vandenberg Air Force Base (VAFB). In the first experiment, a single recirculating well pair with bromide tracer and oxygen amendment successfully delivered oxygen to the subsurface for 42 days. TBA concentrations were reduced from approximately 500 μg/L to below the detection limit within the treatment zone and the treated water was detected in a monitoring transect several meters downgradient. In the second experiment, a site-calibrated model was used to design a double recirculating well pair with oxygen amendment, which successfully delivered oxygen to the subsurface for 291 days and also decreased TBA concentrations to below the detection limit. Methylibium petroleiphilum strain PM1, a known TBA-degrading bacterium, was detectable at the study site but addition of oxygen had little impact on the already low baseline population densities, suggesting that there was not enough carbon within the groundwater plume to support significant new growth in the PM1 population. Given favorable hydrogeologic and geochemical conditions, the use of recirculating well pairs to introduce dissolved oxygen into the subsurface is a viable method to stimulate in situ biodegradation of TBA or other aerobically-degradable aquifer contaminants.

Advances in the steady-state hybrid regime in DIII-D – a fully non-inductive, ELM-suppressed scenario for ITER

DOE PAGES

Petty, Craig C.; Nazikian, Raffi; Park, Jin Myung; ...

2017-07-19

Here, the hybrid regime with beta, collisionality, safety factor and plasma shape relevant to the ITER steady-state mission has been successfully integrated with ELM suppression by applying an odd parity n=3 resonant magnetic perturbation (RMP). Fully non-inductive hybrids in the DIII-D tokamak with high beta (β ≤ 2.8%) and high confinement (98y2 ≤ 1.4) in the ITER similar shape have achieved zero surface loop voltage for up to two current relaxation times using efficient central current drive from ECCD and NBCD. The n=3 RMP causes surprisingly little increase in thermal transport during ELM suppression. Poloidal magnetic flux pumping in hybridmore » plasmas maintains q above 1 without loss of current drive efficiency, except that experiments show that extremely peaked ECCD profiles can create sawteeth. During ECCD, Alfvén eigenmode (AE) activity is replaced by a more benign fishbone-like mode, reducing anomalous beam ion diffusion by a factor of 2. While the electron and ion thermal diffusivities substantially increase with higher ECCD power, the loss of confinement can be offset by the decreased fast ion transport resulting from AE suppression. Extrapolations from DIII-D along a dimensionless parameter scaling path as well as those using self-consistent theory-based modeling show that these ELM-suppressed, fully non-inductive hybrids can achieve the Q = 5 ITER steady-state mission.« less

The Biological Effectiveness of Accelerated Particles for the Induction of Chromosome Damage: Track Structure Effects and Cytogenetic Signatures of High-LET Exposure

NASA Technical Reports Server (NTRS)

George, K.; Hada, M.; Chappell, L.; Cucinotta, F. A.

2012-01-01

Track structure models predict that at a fixed value of LET, particles with lower charge number, Z will have a higher biological effectiveness compared to particles with a higher Z. In this report we investigated how track structure effects induction of chromosomal aberration in human cells. Human lymphocytes were irradiated in vitro with various energies of accelerated iron, silicon, neon, or titanium ions and chromosome damage was assessed in using three color FISH chromosome painting in chemically induced PCC samples collected a first cell division post irradiation. The LET values for these ions ranged from 30 to 195 keV/micrometers. Of the particles studied, Neon ions have the highest biological effectiveness for induction of total chromosome damage, which is consistent with track structure model predictions. For complex-type exchanges 64 MeV/ u Neon and 450 MeV/u Iron were equally effective and induced the most complex damage. In addition we present data on chromosomes exchanges induced by six different energies of protons (5 MeV/u to 2.5 GeV/u). The linear dose response term was similar for all energies of protons suggesting that the effect of the higher LET at low proton energies is balanced by the production of nuclear secondaries from the high energy protons. All energies of protons have a much higher percentage of complex-type chromosome exchanges than gamma rays, signifying a cytogenetic signature for proton exposures.

Determination of cadmium(II), cobalt(II), nickel(II), lead(II), zinc(II), and copper(II) in water samples using dual-cloud point extraction and inductively coupled plasma emission spectrometry.

PubMed

Zhao, Lingling; Zhong, Shuxian; Fang, Keming; Qian, Zhaosheng; Chen, Jianrong

2012-11-15

A dual-cloud point extraction (d-CPE) procedure has been developed for simultaneous pre-concentration and separation of heavy metal ions (Cd2+, Co2+, Ni2+, Pb2+, Zn2+, and Cu2+ ion) in water samples by inductively coupled plasma optical emission spectrometry (ICP-OES). The procedure is based on forming complexes of metal ion with 8-hydroxyquinoline (8-HQ) into the as-formed Triton X-114 surfactant rich phase. Instead of direct injection or analysis, the surfactant rich phase containing the complexes was treated by nitric acid, and the detected ions were back extracted again into aqueous phase at the second cloud point extraction stage, and finally determined by ICP-OES. Under the optimum conditions (pH=7.0, Triton X-114=0.05% (w/v), 8-HQ=2.0×10(-4) mol L(-1), HNO3=0.8 mol L(-1)), the detection limits for Cd2+, Co2+, Ni2+, Pb2+, Zn2+, and Cu2+ ions were 0.01, 0.04, 0.01, 0.34, 0.05, and 0.04 μg L(-1), respectively. Relative standard deviation (RSD) values for 10 replicates at 100 μg L(-1) were lower than 6.0%. The proposed method could be successfully applied to the determination of Cd2+, Co2+, Ni2+, Pb2+, Zn2+, and Cu2+ ion in water samples. Copyright © 2012 Elsevier B.V. All rights reserved.

Effect of Mobile Phone Usage on Nickel Ions Release and pH of Saliva in Patients Undergoing Fixed Orthodontic Treatment.

PubMed

Nanjannawar, Lalita Girish; Girme, Tejashree Suresh; Agrawal, Jiwanasha Manish; Agrawal, Manish Suresh; Fulari, Sangamesh Gurunath; Shetti, Shraddha Subhash; Kagi, Vishwal Ajith

2017-09-01

Hand held mobile phones are presently the most popular means of communication worldwide and have transformed our lives in many aspects. The widespread use of such devices have resulted in growing concerns regarding harmful effects of radiations emitted by them. This study was designed to evaluate the effects of mobile phone usage on nickel ion release as well as pH of saliva in patients with fixed orthodontic appliances. To assess the level of nickel ions in saliva and pH of saliva in mobile phone users undergoing fixed orthodontic treatment using inductively coupled plasma atomic emission spectrometry. A total of 42 healthy patients with fixed orthodontic appliance in mouth for a duration of six to nine months were selected for the study. They were divided into experimental group (n=21) consisting of mobile phone users and control group (n=21) of non mobile phone users. Saliva samples were collected from both the groups and nickel ion levels were measured using inductively coupled plasma-mass spectroscopy. The pH values were also assessed for both groups using pH meter. Unpaired t-test was used for the data analysis. Statistical analysis revealed that though the pH levels were reduced and the nickel ion levels were higher in the experimental group compared to the control group, the results were non significant. Mobile phone usage may affect the pH of saliva and result in increased release of nickel ions in saliva of patients with fixed orthodontic appliances in the oral cavity.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Friedman, A.; Barnard, J.J.; Briggs, R.J.

The Heavy Ion Fusion Science Virtual National Laboratory (HIFS-VNL), a collaborationof LBNL, LLNL, and PPPL, has achieved 60-fold pulse compression of ion beams on the Neutralized Drift Compression eXperiment (NDCX) at LBNL. In NDCX, a ramped voltage pulse from an induction cell imparts a velocity"tilt" to the beam; the beam's tail then catches up with its head in a plasma environment that provides neutralization. The HIFS-VNL's mission is to carry out studies of Warm Dense Matter (WDM) physics using ion beams as the energy source; an emerging thrust is basic target physics for heavy ion-driven Inertial Fusion Energy (IFE). Thesemore » goals require an improved platform, labeled NDCX-II. Development of NDCX-II at modest cost was recently enabled by the availability of induction cells and associated hardware from the decommissioned Advanced Test Accelerator (ATA) facility at LLNL. Our initial physics design concept accelerates a ~;;30 nC pulse of Li+ ions to ~;;3 MeV, then compresses it to ~;;1 ns while focusing it onto a mm-scale spot. It uses the ATA cells themselves (with waveforms shaped by passive circuits) to impart the final velocity tilt; smart pulsers provide small corrections. The ATA accelerated electrons; acceleration of non-relativistic ions involves more complex beam dynamics both transversely and longitudinally. We are using analysis, an interactive one-dimensional kinetic simulation model, and multidimensional Warp-code simulations to develop the NDCX-II accelerator section. Both LSP and Warp codes are being applied to the beam dynamics in the neutralized drift and final focus regions, and the plasma injection process. The status of this effort is described.« less

Method of decontaminating a contaminated fluid by using photocatalytic particles

NASA Technical Reports Server (NTRS)

Cooper, Gerald (Inventor); Ratcliff, Matthew A. (Inventor)

1994-01-01

A system for decontaminating the contaminated fluid by using photocatalytic particles. The system includes a reactor tank for holding the contaminated fluid and the photocatalytic particles suspended in the contaminated fluid to form a slurry. Light irradiates the surface of the slurry, thereby activating the photocatalytic properties of the particles. The system also includes stirring blades for continuously agitating the irradiated fluid surface and for maintaining the particles in a suspended state within the fluid. The system also includes a cross flow filter for segregating the fluid (after decomposition) from the semiconductor powder. The cross flow filter is occasionally back flushed to remove any semiconductor powder that might have caked on the filter. The semiconductor powder may be recirculated back to the tank for reuse, or may be stored for future use. A series of such systems may be used to gradually decompose a chemical in the fluid. Preferably, the fluid is pretreated to remove certain metal ions which interfere with the photocatalytic process. Such pretreatment may be accomplished by dispersing semiconductor particles within the fluid, which adsorb ions or photodeposit the metal as the free metal or its insoluble oxide or hydroxide, and then removing the semiconductor particles together with the adsorbed metal ions/oxides/hydroxide/free metal from the fluid. A method of decontaminating a contaminated fluid is also disclosed.

40 CFR 420.101 - Specialized definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... AND STANDARDS IRON AND STEEL MANUFACTURING POINT SOURCE CATEGORY Cold Forming Subcategory § 420.101 Specialized definitions. (a) The term recirculation means those cold rolling operations which include recirculation of rolling solutions at all mill stands. (b) The term combination means those cold rolling...

40 CFR 420.101 - Specialized definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... AND STANDARDS IRON AND STEEL MANUFACTURING POINT SOURCE CATEGORY Cold Forming Subcategory § 420.101 Specialized definitions. (a) The term recirculation means those cold rolling operations which include recirculation of rolling solutions at all mill stands. (b) The term combination means those cold rolling...

40 CFR 420.101 - Specialized definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... AND STANDARDS IRON AND STEEL MANUFACTURING POINT SOURCE CATEGORY Cold Forming Subcategory § 420.101 Specialized definitions. (a) The term recirculation means those cold rolling operations which include recirculation of rolling solutions at all mill stands. (b) The term combination means those cold rolling...

40 CFR 420.101 - Specialized definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... AND STANDARDS IRON AND STEEL MANUFACTURING POINT SOURCE CATEGORY Cold Forming Subcategory § 420.101 Specialized definitions. (a) The term recirculation means those cold rolling operations which include recirculation of rolling solutions at all mill stands. (b) The term combination means those cold rolling...

An Inexpensive Recirculating Aquaculture System with Multiple Use Capabilities.

ERIC Educational Resources Information Center

Scurlock, Gerald Don, Jr.; Cook, S. Bradford; Scurlock, Carrie Ann

1999-01-01

Describes the construction of an inexpensive recirculating aquaculture system that can hold up to 46 pounds of fish, invertebrates, and mussels for classroom use. The system is versatile, requires little maintenance, and can be used for both teaching and research purposes. (WRM)

Transport and recirculation of aerosols off Southern Africa—macroscale plume structure

NASA Astrophysics Data System (ADS)

Tyson, P. D.; D'Abreton, P. C.

A pall of aerosols and trace gases frequently occurs over southern Africa to a depth of ˜500 hPa, blanketing vast areas, particularly in the austral winter and spring. Large-scale offshore transport of these aerosols and trace gases in extremely large plumes from interior continental areas of the subcontinent to the Indian and Atlantic Oceans is a common occurrence. The nature of the transport plumes, their climatology, chemical composition and morphology are discussed. In the vertically integrated, surface-to-500 hPa layer, poleward of about 15° S, transport into the Indian Ocean is shown to be about 60% greater into the Indian Ocean than into the Atlantic Ocean. Recirculation of atmospheric constituents is considered and estimates of aerosol mass fluxes over central southern Africa are presented. Of the total of about 50 Mt yr -1 of aerosols being transported at the central meridian, 44% is shown to be recirculated material. The rest exits the subcontinent directly without recirculation. Preferred plume corridors of exit and entry are postulated for different localities on the east and west coasts. Two case studies of east- and west-coast plumes apparently flowing uniformly out of southern Africa are examined. The illusion of uniformity in plume structure is shown to be misleading. Both plumes are shown to be above and separated from the marine boundary layer. Each is over 1500 km in width and 3-5 km deep. Likewise, both are capped by absolutely stable layers at ˜500 hPa and exhibit a complex structure of both outflowing aerosols and trace gases and inflowing, recycled and recirculated material. Indications of the composition of the recirculated material are given and implications of the plume transports are considered.

Removal of Gross Air Embolization from Cardiopulmonary Bypass Circuits with Integrated Arterial Line Filters: A Comparison of Circuit Designs.

PubMed

Reagor, James A; Holt, David W

2016-03-01

Advances in technology, the desire to minimize blood product transfusions, and concerns relating to inflammatory mediators have lead many practitioners and manufacturers to minimize cardiopulmonary bypass (CBP) circuit designs. The oxygenator and arterial line filter (ALF) have been integrated into one device as a method of attaining a reduction in prime volume and surface area. The instructions for use of a currently available oxygenator with integrated ALF recommends incorporating a recirculation line distal to the oxygenator. However, according to an unscientific survey, 70% of respondents utilize CPB circuits incorporating integrated ALFs without a path of recirculation distal to the oxygenator outlet. Considering this circuit design, the ability to quickly remove a gross air bolus in the blood path distal to the oxygenator may be compromised. This in vitro study was designed to determine if the time required to remove a gross air bolus from a CPB circuit without a path of recirculation distal to the oxygenator will be significantly longer than that of a circuit with a path of recirculation distal to the oxygenator. A significant difference was found in the mean time required to remove a gross air bolus between the circuit designs (p = .0003). Additionally, There was found to be a statistically significant difference in the mean time required to remove a gross air bolus between Trial 1 and Trials 4 (p = .015) and 5 (p =.014) irrespective of the circuit design. Under the parameters of this study, a recirculation line distal to an oxygenator with an integrated ALF significantly decreases the time it takes to remove an air bolus from the CPB circuit and may be safer for clinical use than the same circuit without a recirculation line.

Impact of different supply air and recirculating air filtration systems on stable climate, animal health, and performance of fattening pigs in a commercial pig farm

PubMed Central

Wenke, Cindy; Pospiech, Janina; Reutter, Tobias; Altmann, Bettina; Truyen, Uwe

2018-01-01

Biosecurity is defined as the implementation of measures that reduce the risk of disease agents being introduced and/or spread. For pig production, several of these measures are routinely implemented (e.g. cleaning, disinfection, segregation). However, air as a potential vector of pathogens has long been disregarded. Filters for incoming and recirculating air were installed into an already existing ventilation plant at a fattening piggery (3,840 pigs at maximum) in Saxony, Germany. Over a period of three consecutive fattening periods, we evaluated various parameters including air quality indices, environmental and operating parameters, and pig performance. Animal data regarding respiratory diseases, presence of antibodies against influenza A viruses, PRRSV, and Actinobacillus pleuropneumoniae and lung health score at slaughter were recorded, additionally. There were no significant differences (p = 0.824) in total bacterial counts between barns with and without air filtration. Recirculating air filtration resulted in the lowest total dust concentration (0.12 mg/m3) and lung health was best in animals from the barn equipped with recirculating air filtration modules. However, there was no difference in animal performance. Antibodies against all above mentioned pathogens were detected but mostly animals were already antibody-positive at re-stocking. We demonstrated that supply air filtration as well as recirculating air filtration technique can easily be implemented in an already existing ventilation system and that recirculating air filtration resulted in enhanced lung health compared to supply air-filtered and non-filtered barns. A more prominent effect might have been obtained in a breeding facility because of the longer life span of sows and a higher biosecurity level with air filtration as an add-on measure. PMID:29558482

Investigation of mechanism of anode plasma formation in ion diode with dielectric anode

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pushkarev, A., E-mail: aipush@mail.ru

The results of investigation of the anode plasma formation in a diode with a passive anode in magnetic insulation mode are presented. The experiments have been conducted using the BIPPAB-450 ion accelerator (350–400 kV, 6–8 kA, 80 ns) with a focusing conical diode with B{sub r} external magnetic field (a barrel diode). For analysis of plasma formation at the anode and the distribution of the ions beam energy density, infrared imaging diagnostics (spatial resolution of 1–2 mm) is used. For analysis of the ion beam composition, time-of-flight diagnostics (temporal resolution of 1 ns) were used. Our studies have shown that when the magnetic induction inmore » the A-C gap is much larger than the critical value, the ion beam energy density is close to the one-dimensional Child-Langmuir limit on the entire working surface of the diode. Formation of anode plasma takes place only by the flashover of the dielectric anode surface. In this mode, the ion beam consists primarily of singly ionized carbon ions, and the delay of the start of formation of the anode plasma is 10–15 ns. By reducing the magnetic induction in the A-C gap to a value close to the critical one, the ion beam energy density is 3–6 times higher than that calculated by the one-dimensional Child-Langmuir limit, but the energy density of the ion beam is non-uniform in cross-section. In this mode, the anode plasma formation occurs due to ionization of the anode material with accelerated electrons. In this mode, also, the delay in the start of the formation of the anode plasma is much smaller and the degree of ionization of carbon ions is higher. In all modes occurred effective suppression of the electronic component of the total current, and the diode impedance was 20–30 times higher than the values calculated for the mode without magnetic insulation of the electrons. The divergence of the ion beam was 4.5°–6°.« less

Ion behaviour in pulsed plasma regime by means of Time-resolved energy mass spectroscopy (TREMS) applied to an industrial radiofrequency Plasma Immersion Ion Implanter PULSION registered

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carrere, M.; Kaeppelin, V.; Torregrosa, F.

2006-11-13

In order to face the requirements for P+/N junctions requested for < 45 nm ITRS nodes, new doping techniques are studied. Among them Plasma Immersion Ion Implantation (PIII) has been largely studied. IBS has designed and developed its own PIII machine named PULSION registered . This machine is using a pulsed plasma. As other modem technological applications of low pressure plasma, PULSION registered needs a precise control over plasma parameters in order to optimise process characteristics. In order to improve pulsed plasma discharge devoted to PIII, a nitrogen pulsed plasma has been studied in the inductively coupled plasma (ICP) ofmore » PULSION registered and an argon pulsed plasma has been studied in the helicon discharge of the laboratory reactor of LPIIM (PHYSIS). Measurements of the Ion Energy Distribution Function (IEDF) with EQP300 (Hidden) have been performed in both pulsed plasma. This study has been done for different energies which allow to reconstruct the IEDF resolved in time (TREMS). By comparing these results, we found that the beginning of the plasma pulse, named ignition, exhaust at least three phases, or more. All these results allowed us to explain plasma dynamics during the pulse while observing transitions between capacitive and inductive coupling. This study leads in a better understanding of changes in discharge parameters as plasma potential, electron temperature, ion density.« less

29 CFR 1910.1025 - Lead.

Code of Federal Regulations, 2010 CFR

2010-07-01

... reflect the current status of the program. (4) Mechanical ventilation. (i) When ventilation is used to...) Recirculation of air. If air from exhaust ventilation is recirculated into the workplace, the employer shall... protective clothing or equipment of the potentially harmful effects of exposure to lead. (vii) The employer...

29 CFR 1910.1025 - Lead.

Code of Federal Regulations, 2012 CFR

2012-07-01

... reflect the current status of the program. (4) Mechanical ventilation. (i) When ventilation is used to...) Recirculation of air. If air from exhaust ventilation is recirculated into the workplace, the employer shall... protective clothing or equipment of the potentially harmful effects of exposure to lead. (vii) Labeling of...

29 CFR 1910.1025 - Lead.

Code of Federal Regulations, 2013 CFR

2013-07-01

... reflect the current status of the program. (4) Mechanical ventilation. (i) When ventilation is used to...) Recirculation of air. If air from exhaust ventilation is recirculated into the workplace, the employer shall... protective clothing or equipment of the potentially harmful effects of exposure to lead. (vii) Labeling of...

29 CFR 1910.1025 - Lead.

Code of Federal Regulations, 2011 CFR

2011-07-01

... reflect the current status of the program. (4) Mechanical ventilation. (i) When ventilation is used to...) Recirculation of air. If air from exhaust ventilation is recirculated into the workplace, the employer shall... protective clothing or equipment of the potentially harmful effects of exposure to lead. (vii) The employer...

29 CFR 1910.1025 - Lead.

Code of Federal Regulations, 2014 CFR

2014-07-01

... reflect the current status of the program. (4) Mechanical ventilation. (i) When ventilation is used to...) Recirculation of air. If air from exhaust ventilation is recirculated into the workplace, the employer shall... protective clothing or equipment of the potentially harmful effects of exposure to lead. (vii) Labeling of...

33 CFR 159.127 - Safety coliform count: Recirculating devices.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Safety coliform count: Recirculating devices. 159.127 Section 159.127 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) POLLUTION MARINE SANITATION DEVICES Design, Construction, and Testing § 159...

Modelling mono-digestion of grass silage in a 2-stage CSTR anaerobic digester using ADM1.

PubMed

Thamsiriroj, T; Murphy, J D

2011-01-01

This paper examines 174 days of experimental data and modelling of mono-digestion of grass silage in a two stage wet process with recirculation of liquor; the two vessels have an effective volume of 312 L each. The organic loading rate is initiated at 0.5 kg VS m(-3) d(-1) (first 74 days) and subsequently increased to 1 kg VS m(-3) d(-1). The experimental data was used to generate a mathematical model (ADM1) which was calibrated over the first 74 days of operation. Good accuracy with experimental data was found for the subsequent 100 days. Results of the model would suggest starting the process without recirculation and thus building up the solids content of the liquor. As the level of VFA increases, recirculation should be employed to control VFA. Recirculation also controls solids content and pH. Methane production was estimated at 88% of maximum theoretical production. Copyright © 2010 Elsevier Ltd. All rights reserved.

Saponification pretreatment and solids recirculation as a new anaerobic process for the treatment of slaughterhouse waste.

PubMed

Affes, R; Palatsi, J; Flotats, X; Carrère, H; Steyer, J P; Battimelli, A

2013-03-01

Different configurations of anaerobic process, adapted to the treatment of solid slaughterhouse fatty waste, were proposed and evaluated in this study. The tested configurations are based on the combination of anaerobic digestion with/without waste saponification pretreatment (70 °C during 60 min) and with/without recirculation of the digestate solid fraction (ratio=20% w/w). After an acclimation period of substrate pulses-feeding cycles, the reactors were operated in a semi-continuous feeding mode, increasing organic loading rates along experimental time. The degradation of the raw substrate was shown to be the bottleneck of the whole process, obtaining the best performance and process yields in the reactor equipped with waste pretreatment and solids recirculation. Saponification promoted the emulsification and bioavailability of solid fatty residues, while recirculation of solids minimized the substrate/biomass wash-out and induced microbial adaptation to the treatment of fatty substrates. Copyright © 2013 Elsevier Ltd. All rights reserved.

Experimental study of the effects of secondary air on the emissions and stability of a lean premixed combustor

NASA Technical Reports Server (NTRS)

Roffe, G.; Raman, R. S. V.

1981-01-01

Tests were run using a perforated plate flameholder with a relatively short attached recirculation zone and a vee gutter flameholder with a relatively long attached recirculation zone. Combustor streamlines were traced in cold flow tests at ambient pressure. The amount of secondary air entrainment in the recirculation zones of the flameholders was determined by tracer gas testing at cold flow ambient pressure conditions. Combustion tests were caried out at entrance conditions of 0.5 MPa/630K and emission of NOx, CO and unburned hydrocarbons were measured along with lean stability and flashback limits. The degree of entrainment increases as dilution air injection decreases. Flashback appears to be a function of overall equivalence ratio and resistance to flashback increases with increasing combustor entrance velocity. Lean stability limit appears to be a function of both primary zone and flameholder recirculation zone equivalence ratios and resistance to lean blowout increases with increasing combustor entrance velocity.

Flow visualization and flow field measurements of a 1/12 scale tilt rotor aircraft in hover

NASA Technical Reports Server (NTRS)

Coffen, Charles D.; George, Albert R.; Hardinge, Hal; Stevenson, Ryan

1991-01-01

The results are given of flow visualization studies and inflow velocity field measurements performed on a 1/12 scale model of the XV-15 tilt rotor aircraft in the hover mode. The complex recirculating flow due to the rotor-wake-body interactions characteristic of tilt rotors was studied visually using neutrally buoyant soap bubbles and quantitatively using hot wire anemometry. Still and video photography were used to record the flow patterns. Analysis of the photos and video provided information on the physical dimensions of the recirculating fountain flow and on details of the flow including the relative unsteadiness and turbulence characteristics of the flow. Recirculating flows were also observed along the length of the fuselage. Hot wire anemometry results indicate that the wing under the rotor acts to obstruct the inflow causing a deficit in the inflow velocities over the inboard region of the model. Hot wire anemometry also shows that the turbulence intensities in the inflow are much higher in the recirculating fountain reingestion zone.

Laser singular Theta-pinch

NASA Astrophysics Data System (ADS)

Okulov, A. Yu.

2010-10-01

The interaction of the two counter-propagating ultrashort laser pulses with singular wavefronts in the thin slice of the underdense plasma is considered. It is shown that ion-acoustic wave is excited via Brillouin three-wave resonance by corkscrew interference pattern of paraxial singular laser beams. The orbital angular momentum carried by light is transferred to plasma ion-acoustic vortex. The rotation of the density perturbations of electron fluid is the cause of helical current which produces the kilogauss axial quasi-static magnetic field. The exact analytical configurations are presented for an ion-acoustic current field and magnetic induction. The range of experimentally accessible parameters is evaluated.

The Detection of Negative Ions by Inductively Coupled Plasma-Mass Spectrometry

DTIC Science & Technology

1988-07-11

INDUCTIVELY COUPLED PLASMA-MASS SPECTROMETRY by George H. Vickers, Daniel A. Wilson, and Gary M. Hieftje Aooesston For Accepted for Publication Dao s...PERSONAL AUTHOR(S) 7’ George H. Vickers, Daniel A. Wilson, and GayYM. Hieftje 13a TYPE OF REPORT 13b. TIME COVERED./ 14. DATE OF REPORT (Year, Month...UNLIMITED 0] AME AS RP’r [] DTC USERS Distribution Unlimited - 22a NAME OF RESPONSIBLE INOIVIDUAL 22b TELEPHONE (Include Area Code) 22c OFFICE SYMBOL Gary M

Thermal Control and Enhancement of Heat Transport Capacity of Two-Phase Loops With Electrohydrodynamic Conduction Pumping

NASA Technical Reports Server (NTRS)

Seyed-Yagoobi, J.; Didion, J.; Ochterbeck, J. M.; Allen, J.

2000-01-01

There are three kinds of electrohydrodynamics (EHD) pumping based on Coulomb force: induction pumping, ion-drag pumping, and pure conduction pumping. EHD induction pumping relies on the generation of induced charges. This charge induction in the presence of an electric field takes place due to a non-uniformity in the electrical conductivity of the fluid which can be caused by a non-uniform temperature distribution and/or an inhomogeneity of the fluid (e.g. a two-phase fluid). Therefore, induction pumping cannot be utilized in an isothermal homogeneous liquid. In order to generate Coulomb force, a space charge must be generated. There are two main mechanisms for generating a space charge in an isothermal liquid. The first one is associated with the ion injection at a metal/liquid interface and the related pumping is referred to as ion-drag pumping. Ion-drag pumping is not desirable because it can deteriorate the electrical properties of the working fluid. The second space charge generation mechanism is associated with the heterocharge layers of finite thickness in the vicinity of the electrodes. Heterocharge layers result from dissociation of the neutral electrolytic species and recombination of the generated ions. This type of pumping is referred to as pure conduction pumping. This project investigates the EHD pumping through pure conduction phenomenon. Very limited work has been conducted in this field and the majority of the published papers in this area have mistakenly assumed that the electrostriction force was responsible for the net flow generated in an isothermal liquid. The main motivation behind this study is to investigate an EHD conduction pump for a two-phase loop to be operated in the microgravity environment. The pump is installed in the liquid return passage (isothermal liquid) from the condenser section to the evaporator section. Unique high voltage and ground electrodes have been designed that generate sufficient pressure heads with very low electric power requirements making the EHD conduction pumping attractive to applications such as two-phase systems (e.g. capillary pumped loops and heat pipes). Currently, the EHD conduction pump performance is being tested on a two-phase loop under various operating conditions in the laboratory environment. The simple non-mechanical and lightweight design of the EHD pump combined with the rapid control of performance by varying the applied electric field, low power consumption, and reliability offer significant advantages over other pumping mechanisms; particularly in reduced gravity applications.

Ion beam modification of biological materials in nanoscale

NASA Astrophysics Data System (ADS)

Yu, L. D.; Anuntalabhochai, S.

2012-07-01

Ion interaction with biological objects in nanoscale is a novel research area stemming from applications of low-energy ion beams in biotechnology and biomedicine. Although the ion beam applications in biotechnology and biomedicine have achieved great successes, many mechanisms remain unclear and many new applications are to be explored. We have carried out some research on exploring the mechanisms and new applications besides attaining ion beam induction of mutation breeding and gene transformation. In the studies on the mechanisms, we focused our investigations on the direct interaction in nanoscale between ions and biological living materials. Our research topics have included the low-energy ion range in DNA, low-energy ion or neutral beam bombardment effect on DNA topological form change and mutation, low-energy ion or neutral beam bombardment effect on the cell envelope and gene transformation, and molecular dynamics simulation of ultra-low-energy ion irradiation of DNA. In the exploration of new applications, we have started experiments on ion irradiation or bombardment, in the nanoscaled depth or area, of human cells for biomedical research. This paper introduces our experiments and reports interesting results.

Boosting devices with integral features for recirculating exhaust gas

DOEpatents

Wu, Ko -Jen

2015-09-15

According to one embodiment of the invention, a compressor housing includes a compressor inlet in fluid communication with a compressor volute configured to house a compressor wheel, the compressor inlet configured to provide a first air flow to the compressor wheel and a compressor outlet in fluid communication with the compressor volute, the compressor outlet configured to direct a compressed gas to an intake manifold. The compressor housing further includes an exhaust gas recirculation inlet port in fluid communication with the compressor volute, the exhaust gas recirculation inlet port being configured to combine an exhaust gas flow with the air flow to the compressor wheel.

Method and device for measuring single-shot transient signals

DOEpatents

Yin, Yan

2004-05-18

Methods, apparatus, and systems, including computer program products, implementing and using techniques for measuring multi-channel single-shot transient signals. A signal acquisition unit receives one or more single-shot pulses from a multi-channel source. An optical-fiber recirculating loop reproduces the one or more received single-shot optical pulses to form a first multi-channel pulse train for circulation in the recirculating loop, and a second multi-channel pulse train for display on a display device. The optical-fiber recirculating loop also optically amplifies the first circulating pulse train to compensate for signal losses and performs optical multi-channel noise filtration.

Generation and Maintenance of Recirculations by Gulf Stream Instabilities

DTIC Science & Technology

1999-02-01

Francois Primeau for endless discus- sions of various scientific problems, Kirill Pankratov for useful advice on the numerical methods in fluid...recirculation. J. Phys. Oceanogr., 18, 662-682. [7] Davis C. A. and K. A. Emanuel, 1991 : Potential vorticity diagnostics of cyclo- genesis. Mon. Weather. Rev

Nitrate removal effectiveness of fluidized sulfur-based autotrophic denitrification biofilters for recirculating aquaculture systems

USDA-ARS?s Scientific Manuscript database

There is a need to develop practical methods to reduce nitrate -nitrogen loads from recirculating aqua-culture systems to facilitate increased food protein production simultaneously with attainment of water quality goals. The most common wastewater denitrification treatment systems utilize methanol-...

Disinfection of water in recirculating aquaculture systems with peracetic acid (PAA)

USDA-ARS?s Scientific Manuscript database

The disinfection behaviour of peracetic acid (PAA) in recirculating aquaculture systems (RAS) was investigated. Peracetic acid is a strong oxidizing agent found in various concentrations in different products. Three Wofasteril PAA products (E400 (c), Lspecical; AC 150) were tested in vitro for the...

Experimental Bleaching of a Reef-Building Coral Using a Simplified Recirculating Laboratory Exposure System

EPA Science Inventory

Determining stressor-response relationships in reef building corals is a critical need for researchers because of global declines in coral reef ecosystems. A simplified recirculating coral exposure system for laboratory testing of a diversity of species and morphologies of reef b...

Effect of exhaust gas recirculation on emissions from a flame-tube combustor using Liquid Jet A fuel

NASA Technical Reports Server (NTRS)

Marek, C. J.; Tacina, R. R.

1976-01-01

The effects of uncooled exhaust gas recirculation as an inert diluent on emissions of oxides of nitrogen (NO + NO2) and on combustion efficiency were investigated. Ratios of recirculated combustion products to inlet airflow were varied from 10 to 80 percent by using an inlet air ejector nozzle. Liquid Jet A fuel was used. The flame-tube combustor was 10.2 cm in diameter. It was operated with and without a flameholder present. The combustor pressure was maintained constant at 0.5 MPa. The equivalence ratio was varied from 0.3 to 1.0. The inlet air temperature was varied from 590 to 800 K, and the reference velocity from 10 to 30 m/sec. Increasing the percent recirculation from 10 to 25 had the following effects: (1) the peak NOx emission was decreased by 37 percent, from 8 to 5 g NO2/kg fuel, at an inlet air temperature of 590 K and a reference velocity of 15 m/sec; (2) the combustion efficiency was increased, particularly at the higher equivalence ratios; and (3) for a high combustion efficiency of greater than 99.5 percent, the range of operation of the combustor was nearly doubled in terms of equivalence ratio. Increasing the recirculation from 25 to 50 percent did not change the emissions significantly.

Ocean Bottom Pressure Variation Associated with the Large Meander of the Kuroshio South of Japan in 2004-2005

NASA Astrophysics Data System (ADS)

Nagano, A.; Hasegawa, T.; Matsumoto, H.; Ariyoshi, K.

2016-02-01

The Kuroshio, the western boundary current of the North Pacific subtropical gyre, takes a stable meandering path off the southern coast of Japan, called the large meander (LM), on interannual to decadal timescales. The LM of the Kuroshio formed in July 2004 associated with the intensified anticyclonic recirculation gyre south of the Kuroshio, and gradually decayed in the latter half of 2005. The variations of the Kuroshio and the southern recirculating currents may be related to deep currents, which are expected to be associated with bottom pressure (BP) variation. In order to examine the variation of BP associated with the variations of the sea surface currents, we analyzed data of eleven pressure sensors equipped to inverted echo sounders deployed from July 2004 to October 2006. An abrupt enhancement of BP is found on the continental slope off Shikoku, lagging a few months behind an elevation of sea surface height (SSH) due to the onshore shift of the recirculation gyre associated with the LM formation. Subsequently, BP beneath the recirculation gyre dwindles, leading the gradual depression of SSH due to the decay of the LM. The relationship between BP and SSH may suggest that the occurrence and decay of the LM depend on the extension of the recirculation gyre current down to the ocean bottom.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hamdi, Dounia Houria; Chevalier, François; Groetz, Jean-Emmanuel

Purpose: Particle therapy using carbon ions (C-ions) has been successfully used in the treatment of tumors resistant to conventional radiation therapy. However, the potential side effects to healthy cartilage exposed to lower linear energy transfer (LET) ions in the beam track before the tumor have not been evaluated. The aim of the present study was to assess the extent of damage after C-ion irradiation in a 3-dimensional (3D) cartilage model close to human homeostasis. Methods and Materials: Primary human articular chondrocytes from a healthy donor were cultured in a collagen scaffold to construct a physioxic 3D cartilage model. A 2-dimensionalmore » (2D) culture was used as a reference. The cells were irradiated with a single dose of a monoenergetic C-ion beam with a LET of approximatively 30 keV/μm. This LET corresponds to the entrance channel of C-ions in the shallow healthy tissues before the spread-out Bragg peak (∼100 keV/μm) during hadron therapy protocols. The same dose of X-rays was used as a reference. Survival, cell death, and senescence assays were performed. Results: As expected, in the 2D culture, C-ions were more efficient than X-rays in reducing cell survival with a relative biological effectiveness of 2.6. This correlated with stronger radiation-induced senescence (two-fold) but not with higher cell death induction. This differential effect was not reflected in the 3D culture. Both ionizing radiation types induced a comparable rate of senescence induction in the 3D model. Conclusions: The greater biological effectiveness of C-ions compared with low LET radiation when evaluated in treatment planning systems might be misevaluated using 2D culture experiments. Radiation-induced senescence is an important factor of potential cartilage attrition. The present data should encourage the scientific community to use relevant models and beams to improve the use of charged particles with better safety for patients.« less

Kinetics of acetaminophen degradation by Fenton oxidation in a fluidized-bed reactor.

PubMed

de Luna, Mark Daniel G; Briones, Rowena M; Su, Chia-Chi; Lu, Ming-Chun

2013-01-01

Acetaminophen (ACT), an analgesic and antipyretic substance, is one of the most commonly detected pharmaceutical compound in surface waters and wastewaters. In this study, fluidized-bed Fenton (FB-Fenton) was used to decompose ACT into its final degradation products. The 1.45-L cylindrical glass reactor had inlet, outlet and recirculating sections. SiO(2) carrier particles were supported by glass beads with 2-4 mm in diameter. ACT concentration was determined by high performance liquid chromatography (HPLC). During the first 40 min of reaction, a fast initial ACT removal was observed and the "two-stage" ACT degradation conformed to a pseudo reaction kinetics. The effects of ferrous ion dosage and [Fe(2+)]/[H(2)O(2)] (FH ratio) were integrated into the derived pseudo second-order kinetic model. A reaction pathway was proposed based on the intermediates detected through SPME/GC-MS. The aromatic intermediates identified were hydroquinone, benzaldehydes and benzoic acids while the non-aromatic substances include alcohols, ketones, aldehydes and carboxylic acids. Rapid initial ACT degradation rate can be accomplished by high initial ferrous ion concentration and/or low FH ratio. Copyright © 2012 Elsevier Ltd. All rights reserved.

Transportation of high-current ion and electron beams in the accelerator drift gap in the presence of an additional electron background

DOE Office of Scientific and Technical Information (OSTI.GOV)

Karas’, V. I., E-mail: karas@kipt.kharkov.ua; Kornilov, E. A.; Manuilenko, O. V.

2015-12-15

The dynamics of a high-current ion beam propagating in the drift gap of a linear induction accelerator with collective focusing is studied using 3D numerical simulations in the framework of the full system of the Vlasov–Maxwell equations (code KARAT). The ion beam is neutralized by a comoving electron beam in the current density and, partially, in space charge, since the velocities of electrons and ions differ substantially. The dynamics of the high-current ion beam is investigated for different versions of additional neutralization of its space charge. It is established that, for a given configuration of the magnetic field and inmore » the presence of a specially programmed injection of additional electrons from the boundary opposite to the ion injection boundary, the angular divergence of the ion beam almost vanishes, whereas the current of the ion beam at the exit from the accelerator drift gap changes insignificantly and the beam remains almost monoenergetic.« less

Transportation of high-current ion and electron beams in the accelerator drift gap in the presence of an additional electron background

NASA Astrophysics Data System (ADS)

Karas', V. I.; Kornilov, E. A.; Manuilenko, O. V.; Tarakanov, V. P.; Fedorovskaya, O. V.

2015-12-01

The dynamics of a high-current ion beam propagating in the drift gap of a linear induction accelerator with collective focusing is studied using 3D numerical simulations in the framework of the full system of the Vlasov-Maxwell equations (code KARAT). The ion beam is neutralized by a comoving electron beam in the current density and, partially, in space charge, since the velocities of electrons and ions differ substantially. The dynamics of the high-current ion beam is investigated for different versions of additional neutralization of its space charge. It is established that, for a given configuration of the magnetic field and in the presence of a specially programmed injection of additional electrons from the boundary opposite to the ion injection boundary, the angular divergence of the ion beam almost vanishes, whereas the current of the ion beam at the exit from the accelerator drift gap changes insignificantly and the beam remains almost monoenergetic.

Simple Signaling Molecules for Inductive Bone Regenerative Engineering

PubMed Central

Nelson, Stephen J.; Deng, Meng; Sethuraman, Swaminathan; Doty, Stephen B.; Lo, Kevin W. H.; Khan, Yusuf M.; Laurencin, Cato T.

2014-01-01

With greater than 500,000 orthopaedic procedures performed in the United States each year requiring a bone graft, the development of novel graft materials is necessary. We report that some porous polymer/ceramic composite scaffolds possess intrinsic osteoinductivity as shown through their capacity to induce in vivo host osteoid mineralization and in vitro stem cell osteogenesis making them attractive synthetic bone graft substitutes. It was discovered that certain low crystallinity ceramics partially dissociate into simple signaling molecules (i.e., calcium and phosphate ions) that induce stem cells to endogenously produce their own osteoinductive proteins. Review of the literature has uncovered a variety of simple signaling molecules (i.e., gases, ions, and redox reagents) capable of inducing other desirable stem cell differentiation through endogenous growth factor production. Inductive simple signaling molecules, which we have termed inducerons, represent a paradigm shift in the field of regenerative engineering where they can be utilized in place of recombinant protein growth factors. PMID:25019622

Inactivation, DNA double strand break induction and their rejoining in bacterial cells irradiated with heavy ions

NASA Technical Reports Server (NTRS)

Schaefer, M.; Zimmermann, H.; Schmitz, C.

1994-01-01

Besides inactivation one of the major interests in our experiments is to study the primary damage in the DNA double strand breaks (DSB) after heavy ion irradiation. These damages lead not only to cell death but also under repair activities to mutations. In further experiments we have investigated the inactivation with two different strains of Deinococcus radiodurans (R1, Rec 30) and the induction of DSB as well as the rejoining of DSB in stationary cells of E. coli (strain B/r) irradiated with radiations of different quality. In the latter case irradiations were done so that the cell survival was roughly at the same level. We measured the DSB using the pulse field gelelectrophoresis which allows to separate between intact (circular) and damaged (linear) DNA. The irradiated cells were transferred to NB medium and incubated for different times to allow rejoining.

Investigation of Saltwater Intrusion and Recirculation of Seawater for Henry Constant Dispersion and Velocity-Dependent Dispersion Problems and Field-Scale Problem

NASA Astrophysics Data System (ADS)

Motz, L. H.; Kalakan, C.

2013-12-01

Three problems regarding saltwater intrusion, namely the Henry constant dispersion and velocity-dependent dispersion problems and a larger, field-scale velocity-dependent dispersion problem, have been investigated to determine quantitatively how saltwater intrusion and the recirculation of seawater at a coastal boundary are related to the freshwater inflow and the density-driven buoyancy flux. Based on dimensional analysis, saltwater intrusion and the recirculation of seawater are dependent functions of the independent ratio of freshwater advective flux relative to the density-driven vertical buoyancy flux, defined as az (or a for an isotropic aquifer), and the aspect ratio of horizontal and vertical dimensions of the cross-section. For the Henry constant dispersion problem, in which the aquifer is isotropic, saltwater intrusion and recirculation are related to an additional independent dimensionless parameter that is the ratio of the constant dispersion coefficient treated as a scalar quantity, the porosity, and the freshwater advective flux, defined as b. For the Henry velocity-dependent dispersion problem, the ratio b is zero, and saltwater intrusion and recirculation are related to an additional independent dimensionless parameter that is the ratio of the vertical and horizontal dispersivities, or rα = αz/αx. For an anisotropic aquifer, saltwater intrusion and recirculation are also dependent on the ratio of vertical and horizontal hydraulic conductivities, or rK = Kz/Kx. For the field-scale velocity-dependent dispersion problem, saltwater intrusion and recirculation are dependent on the same independent ratios as the Henry velocity-dependent dispersion problem. In the two-dimensional cross-section for all three problems, freshwater inflow occurs at an upgradient boundary, and recirculated seawater outflow occurs at a downgradient coastal boundary. The upgradient boundary is a specified-flux boundary with zero freshwater concentration, and the downgradient boundary is a specified-head boundary with a specified concentration equal to seawater. Equivalent freshwater heads are specified at the downstream boundary to account for density differences between freshwater and saltwater at the downstream boundary. The three problems were solved using the numerical groundwater flow and transport code SEAWAT for two conditions, i.e., first for the uncoupled condition in which the fluid density is constant and thus the flow and transport equations are uncoupled in a constant-density flowfield, and then for the coupled condition in which the fluid density is a function of the total dissolved solids concentration and thus the flow and transport equations are coupled in a variable-density flowfield. A wide range of results for the landward extent of saltwater intrusion and the amount of recirculation of seawater at the coastal boundary was obtained by varying the independent dimensionless ratio az (or a in problem one) in all three problems. The dimensionless dispersion ratio b was also varied in problem one, and the dispersivity ratio rα and the hydraulic conductivity ratio rK were also varied in problems two and three.

Aggradation and degradation of alluvial sand deposits, 1965 to 1986, Colorado River, Grand Canyon National Park, Arizona

USGS Publications Warehouse

Schmidt, John C.; Graf, Julia B.

1990-01-01

Alluvial sand deposits along the Colorado River in Grand Canyon National Park are used as campsites and are substrate for vegetation. The largest and most numerous of these deposits are formed in zones of recirculating current that are created downstream from where the channel is constricted by debris fans at tributary mouths. Alluvial sand deposits are classified by location and form. Separation and reattachment deposits are downstream from constrictions within recirculation zones. Separation deposits are near the point of flow separation and typically mantle large debris fans. Reattachment deposits are near the point of flow reattachment and project upstream beneath much of the zone of recirculating current. Upper-pool deposits are upstream from a constriction and are associated with backwaters. Channel-margin deposits line the channel and have the form of terraces. Some are created in small recirculation zones. Reattachment and channel-margin deposits are largest and most numerous in wide reaches, although small channel-margin deposits are used as campsites in the narrow Muav Gorge. Separation deposits are more uniformly distributed throughout Grand Canyon National Park than are other types of deposits. In some narrow reaches where the number of alluvial sand deposits used as campsites is small, separation deposits are a high percentage of the total. During high flows, both separation and reattachment deposits are initially scoured but are subsequently redeposited during flow recession. Sand is also exchanged between the main channel and recirculation zones. The rate of recession of high flows can affect the elevation of alluvial deposits that are left exposed after a flood has passed. Fluctuating flows that follow a period of steady discharge cause initial erosion of separation and reattachment deposits. A part of this eroded sand is transported to the main channel. Therefore, sand is exchanged between the main channel and recirculation zones and redistributed within recirculation zones over a broad range of discharges. Comparison of aerial photographs and reinterpretation of published data concerning changes of alluvial sand deposits following recession of high flows in 1983 and 1984 indicate that sand was eroded from recirculation zones in narrow reaches. In wide reaches, however, aggradation in recirculation zones may have occurred. In narrow reaches, the decrease of reattachment deposits was greater than that of separation deposits. In all reaches, the percentage of separation deposits that maintained a constant area was greater than for other deposits. Separation deposits, therefore, appear to be the most stable of the deposit types. Fluctuating flows between October 1985 and January 1986, which followed the higher and steadier flows of 1983 to 1985, caused erosion throughout the park. For separation deposits, erosion was greatest at those sites where deposition from the 1983 high flows had been greatest. The existing pattern of low campsite availability in narrow reaches and high campsite availability in wide reaches was thus accentuated by the sequence of flows between 1983 and 1985.

Multiple bunch HOM evaluation for ERL cavities

DOE PAGES

Xu, Chen; Ben-Zvi, I.; Blaskiewicz, Michael M.; ...

2017-06-15

In this paper we investigate the effect of the bunch pattern in a linac on the Higher Order Mode (HOM) power generation. The future ERL-based electron–ion collider eRHIC at BNL is used as an illustrative example. This ERL has multiple high current Superconducting Radiofrequency (SRF) 5-cell cavities. The HOM power generated when a single bunch traverses the cavity is estimated by the corresponding loss factor. Multiple re-circulations through the Energy Recovery Linac (ERL) create a specific bunch pattern. In this case the loss factor can be different than the single bunch loss factor. HOM power can vary dramatically when themore » ERL bunch pattern changes. The HOM power generation can be surveyed in the time and frequency domains. We estimate the average HOM power in a 5-cell cavity with different ERL bunch patterns.« less

Multiple bunch HOM evaluation for ERL cavities

NASA Astrophysics Data System (ADS)

Xu, Chen; Ben-Zvi, I.; Blaskiewicz, Michael M.; Hao, Yue; Ptitsyn, Vadim

2017-09-01

In this work we investigate the effect of the bunch pattern in a linac on the Higher Order Mode (HOM) power generation. The future ERL-based electron-ion collider eRHIC at BNL is used as an illustrative example. This ERL has multiple high current Superconducting Radiofrequency (SRF) 5-cell cavities. The HOM power generated when a single bunch traverses the cavity is estimated by the corresponding loss factor. Multiple re-circulations through the Energy Recovery Linac (ERL) create a specific bunch pattern. In this case the loss factor can be different than the single bunch loss factor. HOM power can vary dramatically when the ERL bunch pattern changes. The HOM power generation can be surveyed in the time and frequency domains. We estimate the average HOM power in a 5-cell cavity with different ERL bunch patterns.

Multiple bunch HOM evaluation for ERL cavities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xu, Chen; Ben-Zvi, I.; Blaskiewicz, Michael M.

In this paper we investigate the effect of the bunch pattern in a linac on the Higher Order Mode (HOM) power generation. The future ERL-based electron–ion collider eRHIC at BNL is used as an illustrative example. This ERL has multiple high current Superconducting Radiofrequency (SRF) 5-cell cavities. The HOM power generated when a single bunch traverses the cavity is estimated by the corresponding loss factor. Multiple re-circulations through the Energy Recovery Linac (ERL) create a specific bunch pattern. In this case the loss factor can be different than the single bunch loss factor. HOM power can vary dramatically when themore » ERL bunch pattern changes. The HOM power generation can be surveyed in the time and frequency domains. We estimate the average HOM power in a 5-cell cavity with different ERL bunch patterns.« less

Process Requirements for Achieving Full-Flow Disinfection of Recirculating Water Using Ozonation and UV Irradiation

USDA-ARS?s Scientific Manuscript database

A continuous water disinfection process can be used to prevent the introduction and accumulation of obligate and opportunistic fish pathogens in recirculating aquaculture systems (RAS), especially during a disease outbreak when the causative agent would otherwise proliferate within the system. To p...

Evaluation of commercial marine fish feeds for production of juvenile cobia in recirculating aquaculture systems

USDA-ARS?s Scientific Manuscript database

The effect of feeding three commercially available diets manufactured by three U.S. feed companies on production characteristics and body composition of juvenile cobia Rachycentron canadum reared in recirculating aquaculture systems (RAS) was evaluated in a 57 d growth trial. Juvenile cobia (26.7 +...

Confined Turbulent Swirling Recirculating Flow Predictions. Ph.D. Thesis

NASA Technical Reports Server (NTRS)

Abujelala, M. T.

1984-01-01

Turbulent swirling flow, the STARPIC computer code, turbulence modeling of turbulent flows, the k-xi turbulence model and extensions, turbulence parameters deduction from swirling confined flow measurements, extension of the k-xi to confined swirling recirculating flows, and general predictions for confined turbulent swirling flow are discussed.

Low head oxygenator performance characterization for marine recirculating aquaculture systems

USDA-ARS?s Scientific Manuscript database

This study evaluated the effect of temperature (20 and 25 ºC), salinity (10, 15, and 20 ppt), and dissolved oxygen levels within low head oxygenator (LHO) outlet water on oxygen transfer efficiency (OTE) of LHOs for a planned marine recirculating aquaculture system (RAS). Test results indicated tha...

Observations on side-swimming rainbow trout Oncorhynchus mykiss in water recirculation aquaculture systems

USDA-ARS?s Scientific Manuscript database

During a controlled 6-month study using six replicated water recirculation aquaculture systems (WRAS), it was observed that rainbow trout Oncorhynchus mykiss in all WRAS exhibited a higher-than-normal prevalence of side-swimming (i.e. controlled, forward swimming, but with misaligned orientation suc...

Improvement of anaerobic digester performance by wastewater recirculation through an aerated membrane.

USDA-ARS?s Scientific Manuscript database

Swine wastewater from an anaerobic digester was recirculated through a silicone hose located in an external aeration chamber to determine its effect on wastewater malodorants and biogas composition. The silicone hose acted as a semipermeable membrane for the passage of small molecules. In the first...

40 CFR Table Hh-1 to Subpart Hh of... - Emissions Factors, Oxidation Factors and Methods

Code of Federal Regulations, 2011 CFR

2011-07-01

... evapotranspiration rate exceeds the mean annual precipitation rate plus recirculated leachate. Use the greater value when the potential evapotranspiration rate does not exceed the mean annual precipitation rate plus... value rather than assessing the potential evapotranspiration rate or recirculated leachate rate. [75 FR...

40 CFR Table Hh-1 to Subpart Hh of... - Emissions Factors, Oxidation Factors and Methods

Code of Federal Regulations, 2014 CFR

2014-07-01

... value when the potential evapotranspiration rate exceeds the mean annual precipitation rate plus recirculated leachate. Use the greater value when the potential evapotranspiration rate does not exceed the... recirculation can elect to use the greater value rather than assessing the potential evapotranspiration rate or...

40 CFR Table Hh-1 to Subpart Hh of... - Emissions Factors, Oxidation Factors and Methods

Code of Federal Regulations, 2013 CFR

2013-07-01

... evapotranspiration rate exceeds the mean annual precipitation rate plus recirculated leachate. Use the greater value when the potential evapotranspiration rate does not exceed the mean annual precipitation rate plus... value rather than assessing the potential evapotranspiration rate or recirculated leachate rate. [75 FR...

40 CFR Table Hh-1 to Subpart Hh of... - Emissions Factors, Oxidation Factors and Methods

Code of Federal Regulations, 2012 CFR

2012-07-01

... evapotranspiration rate exceeds the mean annual precipitation rate plus recirculated leachate. Use the greater value when the potential evapotranspiration rate does not exceed the mean annual precipitation rate plus... value rather than assessing the potential evapotranspiration rate or recirculated leachate rate. [75 FR...

Off-flavor characterization and depuration in Atlantic salmon cultured to food-size within closed-containment systems

USDA-ARS?s Scientific Manuscript database

Atlantic salmon are typically cultured in marine net pens. However, technological advancements in recirculating aquaculture systems have increased the feasibility of culturing Atlantic salmon in land-based systems. One problem encountered when fish are harvested from recirculating systems is the pre...

Metal-metal interaction mediates the iron induction of Drosophila MtnB

DOE Office of Scientific and Technical Information (OSTI.GOV)

Qiang, Wenjia; Huang, Yunpeng; Wan, Zhihui

Metallothionein (MT) protein families are a class of small and universal proteins rich in cysteine residues. They are synthesized in response to heavy metal stresses to sequester the toxic ions by metal-thiolate bridges. Five MT family members, namely MtnA, MtnB, MtnC, MtnD and MtnE, have been discovered and identified in Drosophila. These five isoforms of MTs are regulated by metal responsive transcription factor dMTF-1 and play differentiated but overlapping roles in detoxification of metal ions. Previous researches have shown that Drosophila MtnB responds to copper (Cu), cadmium (Cd) and zinc (Zn). Interestingly in this study we found that Drosophila MtnBmore » expression also responds to elevated iron levels in the diet. Further investigations revealed that MtnB plays limited roles in iron detoxification, and the direct binding of MtnB to ferrous iron in vitro is also weak. The induction of MtnB by iron turns out to be mediated by iron interference of other metals, because EDTA at even a partial concentration of that of iron can suppress this induction. Indeed, in the presence of iron, zinc homeostasis is altered, as reflected by expression changes of zinc transporters dZIP1 and dZnT1. Thus, iron-mediated MtnB induction appears resulting from interrupted homeostasis of other metals such as zinc, which in turns induced MtnB expression. Metal-metal interaction may more widely exist than we expected. - Highlights: • Metallothionein B expression is regulated by iron in Drosophila melanogaster. • MtnB has limited physiological roles in iron detoxification. • Binding affinity of MtnB to iron is weak in vitro. • Induction of Drosophila MtnB by iron is mediated indirectly through metal-metal interaction.« less

High charge state carbon and oxygen ions in Earth's equatorial quasi-trapping region

NASA Technical Reports Server (NTRS)

Christon, S. P.; Hamilton, D. C.; Gloeckler, G.; Eastmann, T. E.

1994-01-01

Observations of energetic (1.5 - 300 keV/e) medium-to-high charge state (+3 less than or equal to Q less than or equal to +7) solar wind origin C and O ions made in the quasi-trapping region (QTR) of Earth's magnetosphere are compared to ion trajectories calculated in model equatorial magnetospheric magnetic and electric fields. These comparisons indicate that solar wind ions entering the QTR on the nightside as an energetic component of the plasma sheet exit the region on the dayside, experiencing little or no charge exchange on the way. Measurements made by the CHarge Energy Mass (CHEM) ion spectrometer on board the Active Magnetospheric Particle Tracer Explorer/Charge Composition Explorer (AMPTE/CCE) spacecraft at 7 less than L less than 9 from September 1984 to January 1989 are the source of the new results contained herein: quantitative long-term determination of number densities, average energies, energy spectra, local time distributions, and their variation with geomagnetic disturbance level as indexed by Kp. Solar wind primaries (ions with charge states unchanged) and their secondaries (ions with generally lower charge states produced from primaries in the magnetosphere via charge exchange)are observed throughout the QTR and have distinctly different local time variations that persist over the entire 4-year analysis interval. During Kp larger than or equal to 3 deg intervals, primary ion (e.g., O(+6)) densities exhibit a pronounced predawn maximum with average energy minimum and a broad near-local-noon density minimum with average energy maximum. Secondary ion (e.g., O(+5)) densities do not have an identifiable predawn peak, rather they have a broad dayside maximum peaked in local morning and a nightside minimum. During Kp less than or equal to 2(-) intervals, primary ion density peaks are less intense, broader in local time extent, and centered near midnight, while secondary ion density local time variations diminish. The long-time-interval baseline helps to refine and extend previous observations; for example, we show that ionospheric contribution to O(+3)) is negligible. Through comparison with model ion trajectories, we interpret the lack of pronounced secondary ion density peaks colocated with the primary density peaks to indicate that: (1) negligible charge exchange occurs at L greater than 7, that is, solar wind secondaries are produced at L less than 7, and (2) solar wind secondaries do not form a significant portion of the plasma sheet population injected into the QTR. We conclude that little of the energetic solar wind secondary ion population is recirculated through the magnetosphere.

Are metallothioneins equally good biomarkers of metal and oxidative stress?

PubMed

Figueira, Etelvina; Branco, Diana; Antunes, Sara C; Gonçalves, Fernando; Freitas, Rosa

2012-10-01

Several researchers investigated the induction of metallothioneins (MTs) in the presence of metals, namely Cadmium (Cd). Fewer studies observed the induction of MTs due to oxidizing agents, and literature comparing the sensitivity of MTs to different stressors is even more scarce or even nonexistent. The role of MTs in metal and oxidative stress and thus their use as a stress biomarker, remains to be clearly elucidated. To better understand the role of MTs as a biomarker in Cerastoderma edule, a bivalve widely used as bioindicator, a laboratory assay was conducted aiming to assess the sensitivity of MTs to metal and oxidative stressors. For this purpose, Cd was used to induce metal stress, whereas hydrogen peroxide (H2O2), being an oxidizing compound, was used to impose oxidative stress. Results showed that induction of MTs occurred at very different levels in metal and oxidative stress. In the presence of the oxidizing agent (H2O2), MTs only increased significantly when the degree of oxidative stress was very high, and mortality rates were higher than 50 percent. On the contrary, C. edule survived to all Cd concentrations used and significant MTs increases, compared to the control, were observed in all Cd exposures. The present work also revealed that the number of ions and the metal bound to MTs varied with the exposure conditions. In the absence of disturbance, MTs bound most (60-70 percent) of the essential metals (Zn and Cu) in solution. In stressful situations, such as the exposure to Cd and H2O2, MTs did not bind to Cu and bound less to Zn. When organisms were exposed to Cd, the total number of ions bound per MT molecule did not change, compared to control. However the sort of ions bound per MT molecule differed; part of the Zn and all Cu ions where displaced by Cd ions. For organisms exposed to H2O2, each MT molecule bound less than half of the ions compared to control and Cd conditions, which indicates a partial oxidation of thiol groups in the cysteine residues through ROS scavenging. The present results suggest that MTs are excellent markers of metal stress, but not of oxidative stress. Copyright © 2012 Elsevier Inc. All rights reserved.

Effect of plasma grid bias on extracted currents in the RF driven surface-plasma negative ion source

DOE Office of Scientific and Technical Information (OSTI.GOV)

Belchenko, Yu., E-mail: belchenko@inp.nsk.su; Ivanov, A.; Sanin, A.

2016-02-15

Extraction of negative ions from the large inductively driven surface-plasma negative ion source was studied. The dependencies of the extracted currents vs plasma grid (PG) bias potential were measured for two modifications of radio-frequency driver with and without Faraday screen, for different hydrogen feeds and for different levels of cesium conditioning. The maximal PG current was independent of driver modification and it was lower in the case of inhibited cesium. The maximal extracted negative ion current depends on the potential difference between the near-PG plasma and the PG bias potentials, while the absolute value of plasma potential in the drivermore » and in the PG area is less important for the negative ion production. The last conclusion confirms the main mechanism of negative ion production through the surface conversion of fast atoms.« less

Bayesian Integration and Classification of Composition C-4 Plastic Explosives Based on Time-of-Flight-Secondary Ion Mass Spectrometry and Laser Ablation-Inductively Coupled Plasma Mass Spectrometry.

PubMed

Mahoney, Christine M; Kelly, Ryan T; Alexander, Liz; Newburn, Matt; Bader, Sydney; Ewing, Robert G; Fahey, Albert J; Atkinson, David A; Beagley, Nathaniel

2016-04-05

Time-of-flight-secondary ion mass spectrometry (TOF-SIMS) and laser ablation-inductively coupled plasma mass spectrometry (LA-ICPMS) were used for characterization and identification of unique signatures from a series of 18 Composition C-4 plastic explosives. The samples were obtained from various commercial and military sources around the country. Positive and negative ion TOF-SIMS data were acquired directly from the C-4 residue on Si surfaces, where the positive ion mass spectra obtained were consistent with the major composition of organic additives, and the negative ion mass spectra were more consistent with explosive content in the C-4 samples. Each series of mass spectra was subjected to partial least squares-discriminant analysis (PLS-DA), a multivariate statistical analysis approach which serves to first find the areas of maximum variance within different classes of C-4 and subsequently to classify unknown samples based on correlations between the unknown data set and the original data set (often referred to as a training data set). This method was able to successfully classify test samples of C-4, though with a limited degree of certainty. The classification accuracy of the method was further improved by integrating the positive and negative ion data using a Bayesian approach. The TOF-SIMS data was combined with a second analytical method, LA-ICPMS, which was used to analyze elemental signatures in the C-4. The integrated data were able to classify test samples with a high degree of certainty. Results indicate that this Bayesian integrated approach constitutes a robust classification method that should be employable even in dirty samples collected in the field.

Effect of Mobile Phone Usage on Nickel Ions Release and pH of Saliva in Patients Undergoing Fixed Orthodontic Treatment

PubMed Central

Girme, Tejashree Suresh; Agrawal, Jiwanasha Manish; Agrawal, Manish Suresh; Fulari, Sangamesh Gurunath; Shetti, Shraddha Subhash; Kagi, Vishwal Ajith

2017-01-01

Introduction Hand held mobile phones are presently the most popular means of communication worldwide and have transformed our lives in many aspects. The widespread use of such devices have resulted in growing concerns regarding harmful effects of radiations emitted by them. This study was designed to evaluate the effects of mobile phone usage on nickel ion release as well as pH of saliva in patients with fixed orthodontic appliances. Aim To assess the level of nickel ions in saliva and pH of saliva in mobile phone users undergoing fixed orthodontic treatment using inductively coupled plasma atomic emission spectrometry. Materials and Methods A total of 42 healthy patients with fixed orthodontic appliance in mouth for a duration of six to nine months were selected for the study. They were divided into experimental group (n=21) consisting of mobile phone users and control group (n=21) of non mobile phone users. Saliva samples were collected from both the groups and nickel ion levels were measured using inductively coupled plasma-mass spectroscopy. The pH values were also assessed for both groups using pH meter. Unpaired t-test was used for the data analysis. Results Statistical analysis revealed that though the pH levels were reduced and the nickel ion levels were higher in the experimental group compared to the control group, the results were non significant. Conclusion Mobile phone usage may affect the pH of saliva and result in increased release of nickel ions in saliva of patients with fixed orthodontic appliances in the oral cavity. PMID:29207841

DOE Office of Scientific and Technical Information (OSTI.GOV)

Friedman, A; Barnard, J J; Briggs, R J

The Heavy Ion Fusion Science Virtual National Laboratory (HIFS-VNL), a collaboration of LBNL, LLNL, and PPPL, has achieved 60-fold pulse compression of ion beams on the Neutralized Drift Compression eXperiment (NDCX) at LBNL. In NDCX, a ramped voltage pulse from an induction cell imparts a velocity 'tilt' to the beam; the beam's tail then catches up with its head in a plasma environment that provides neutralization. The HIFS-VNL's mission is to carry out studies of warm dense matter (WDM) physics using ion beams as the energy source; an emerging thrust is basic target physics for heavy ion-driven inertial fusion energymore » (IFE). These goals require an improved platform, labeled NDCX-II. Development of NDCX-II at modest cost was recently enabled by the availability of induction cells and associated hardware from the decommissioned advanced test accelerator (ATA) facility at LLNL. Our initial physics design concept accelerates an {approx} 30 nC pulse of Li{sup +} ions to {approx} 3 MeV, then compresses it to {approx} 1 ns while focusing it onto a mm-scale spot. It uses the ATA cells themselves (with waveforms shaped by passive circuits) to impart the final velocity tilt; smart pulsers provide small corrections. The ATA accelerated electrons; acceleration of non-relativistic ions involves more complex beam dynamics both transversely and longitudinally. We are using an interactive one-dimensional kinetic simulation model and multidimensional Warp-code simulations to develop the NDCX-II accelerator section. Both LSP and Warp codes are being applied to the beam dynamics in the neutralized drift and final focus regions, and the plasma injection process. The status of this effort is described.« less

Magnesium Ion Acts as a Signal for Capsule Induction in Cryptococcus neoformans.

PubMed

Rathore, Sudarshan S; Raman, Thiagarajan; Ramakrishnan, Jayapradha

2016-01-01

Cryptococcal meningitis caused by Cryptococcus neoformans, is a common opportunistic neural infection in immunocompromised individuals. Cryptococcus meningitis is associated with fungal burden with larger capsule size in cerebrospinal fluid (CSF). To understand the role of CSF constituents in capsule enlargement, we have evaluated the effect of artificial CSF on capsule induction in comparison with various other capsule inducing media. Two different strains of C. neoformans, an environmental and a clinical isolates were used in the present study. While comparing the various capsule inducing media for the two different strains of C. neoformans, it was observed that the capsule growth was significantly increased when grown in artificial CSF at pH 5.5, temperature 34°C for ATCC C. neoformans and 37°C for Clinical C. neoformans and with an incubation period of 72 h. In addition, artificial CSF supports biofilm formation in C. neoformans. While investigating the individual components of artificial CSF, we found that Mg(2+) ions influence the capsule growth in both environmental and clinical strains of C. neoformans. To confirm our results we studied the expression of four major CAP genes namely, CAP10, CAP59, CAP60, and CAP64 in various capsule inducing media and in different concentrations of Mg(2+) and Ca(2+). Our results on gene expression suggest that, Mg(2+) does have an effect on CAP gene expression, which are important for capsule biosynthesis and virulence. Our findings on the role of Mg(2+) ion as a signal for capsule induction will promote a way to elucidate the control mechanisms for capsule biosynthesis in C. neoformans.

Advances in the steady-state hybrid regime in DIII-D—a fully non-inductive, ELM-suppressed scenario for ITER

NASA Astrophysics Data System (ADS)

Petty, C. C.; Nazikian, R.; Park, J. M.; Turco, F.; Chen, Xi; Cui, L.; Evans, T. E.; Ferraro, N. M.; Ferron, J. R.; Garofalo, A. M.; Grierson, B. A.; Holcomb, C. T.; Hyatt, A. W.; Kolemen, E.; La Haye, R. J.; Lasnier, C.; Logan, N.; Luce, T. C.; McKee, G. R.; Orlov, D.; Osborne, T. H.; Pace, D. C.; Paz-Soldan, C.; Petrie, T. W.; Snyder, P. B.; Solomon, W. M.; Taylor, N. Z.; Thome, K. E.; Van Zeeland, M. A.; Zhu, Y.

2017-11-01

The hybrid regime with beta, collisionality, safety factor and plasma shape relevant to the ITER steady-state mission has been successfully integrated with ELM suppression by applying an odd parity n  =  3 resonant magnetic perturbation (RMP). Fully non-inductive hybrids in the DIII-D tokamak with high beta (≤ft< β \\right>   ⩽  2.8%) and high confinement (H98y2  ⩽  1.4) in the ITER similar shape have achieved zero surface loop voltage for up to two current relaxation times using efficient central current drive from ECCD and NBCD. The n  =  3 RMP causes surprisingly little increase in thermal transport during ELM suppression. Poloidal magnetic flux pumping in hybrid plasmas maintains q above 1 without loss of current drive efficiency, except that experiments show that extremely peaked ECCD profiles can create sawteeth. During ECCD, Alfvén eigenmode (AE) activity is replaced by a more benign fishbone-like mode, reducing anomalous beam ion diffusion by a factor of 2. While the electron and ion thermal diffusivities substantially increase with higher ECCD power, the loss of confinement can be offset by the decreased fast ion transport resulting from AE suppression. Extrapolations from DIII-D along a dimensionless parameter scaling path as well as those using self-consistent theory-based modeling show that these ELM-suppressed, fully non-inductive hybrids can achieve the Q fus  =  5 ITER steady-state mission.

A dented LH2 recirculation line is removed from Discovery

NASA Technical Reports Server (NTRS)

1999-01-01

Workers with United Space Alliance remove Shuttle Discovery's dented main propulsion system liquid hydrogen recirculation line. From left are James Stickley, George Atkins, and Todd Biddle. The 12-inch-long dent was discovered during routine aft compartment inspections Tuesday, Dec. 7. The line recirculates hydrogen from the Shuttle main engines back to the external tank during prelaunch engine conditioning. The line is being replaced and managers expect the replacement work to take about 3 days, followed by system retests and final aft compartment close-outs. Preliminary assessments reflect a launch date of Space Shuttle Discovery on mission STS-103 no earlier than Dec. 16. STS-103 is the third servicing mission for the Hubble Space Telescope.

Reduced bleed air extraction for DC-10 cabin air conditioning

NASA Technical Reports Server (NTRS)

Newman, W. H.; Viele, M. R.; Hrach, F. J.

1980-01-01

It is noted that a significant fuel savings can be achieved by reducing bleed air used for cabin air conditioning. Air in the cabin can be recirculated to maintain comfortable ventilation rates but the quality of the air tends to decrease due to entrainment of smoke and odors. Attention is given to a development system designed and fabricated under the NASA Engine Component Improvement Program to define the recirculation limit for the DC-10. It is shown that with the system, a wide range of bleed air reductions and recirculation rates is possible. A goal of 0.8% fuel savings has been achieved which results from a 50% reduction in bleed extraction from the engine.

Applications of a new wall function to turbulent flow computations

NASA Astrophysics Data System (ADS)

Chen, Y. S.

1986-01-01

A new wall function approach is developed based on a wall law suitable for incompressible turbulent boundary layers under strong adverse pressure gradients. This wall law was derived from a one-dimensional analysis of the turbulent kinetic energy equation with gradient diffusion concept employed in modeling the near-wall shear stress gradient. Numerical testing cases for the present wall functions include turbulent separating flows around an airfoil and turbulent recirculating flows in several confined regions. Improvements on the predictions using the present wall functions are illustrated. For cases of internal recirculating flows, one modification factor for improving the performance of the k-epsilon turbulence model in the flow recirculation regions is also included.

Observation of reflected waves on the SABRE positive polarity inductive adder MITL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cuneo, M.E.; Poukey, J.W.; Mendel, C.W.

We are studying the coupling of extraction applied-B ion diodes to Magnetically Insulated Transmission Line (MITLs) on the SABRE (Sandia Accelerator and Beam Research Experiment, 6 MV, 300 kA) positive polarity inductive voltage adder. Our goal is to determine conditions under which efficient coupling occurs. The best total power efficiency for an ideal ion diode load (i.e., without parasitic losses) is obtained by maximizing the product of cathode current and gap voltage. MITLs require that the load impedance be undermatched to the self-limited line operating impedance for efficient transfer of power to ion diodes, independent of transit time isolation, andmore » even in the case of multiple cathode system with significant vacuum electron flow. We observe that this undermatched condition results in a reflected wave which decreases the line voltage and gap electron sheath current, and increases the anode and cathode current in a time-dependent way. The MITL diode coupling is determined by the flow impedance at the adder exit. We also show that the flow impedance increases along the extension MITL on SABRE. Experimental measurements of current and peak voltage are compared to analytical models and TWOQUICK 2.5-D PIC code simulations.« less

Determination of trace-level haloacetic acids in drinking water by ion chromatography-inductively coupled plasma mass spectrometry.

PubMed

Liu, Yongjian; Mou, Shifen; Chen, Dengyun

2004-06-11

A new method for the determination of nine haloacetic acids (HAAs) with ion chromatography (IC) coupled to inductively coupled plasma mass spectrometry (ICP-MS) was developed. With the very hydrophilic anion-exchange column and steep gradient of sodium hydroxide, the nine HAAs could be well separated in 15 min. After suppression with an ASRS suppressor that was introduced in between IC and ICP-MS, the background was much decreased, the interference caused by sodium ion present in eluent was removed, and the sensitivities of HAAs were greatly improved. The chlorinated and brominated HAAs could be detected as 35ClO and 79Br without interference of the matrix due to the elemental selective ICP-MS. The detection limits for mono-, di-, trichloroacetic acids were between 15.6 and 23.6 microg/l. For the other six bromine-containing HAAs, the detection limits were between 0.34 and 0.99 microg/l. With the pretreatment of OnGuard Ag cartridge to remove high concentration of chloride in sample, the developed method could be applied to the determination of HAAs in many drinking water matrices.

Induction of micronuclei in human fibroblasts across the Bragg curve of energetic heavy ions

NASA Technical Reports Server (NTRS)

Hada, Megumi; Rusek, Adam; Cucinotta, Francis A.; Wu, Honglu

2006-01-01

The space environment consists of a varying field of radiation particles including high energy ions, with spacecraft shielding material providing the major protection to astronauts from harmful exposure. Unlike low-L or X-rays, the presence of shielding does not always reduce the radiation risks for energetic charged particle exposure. Although the dose delivered by the charged particle increases sharply as the particle approaches the Bragg peak, the Bragg curve does not necessarily represent the biological damage along the particle traversal. The "biological Bragg curve" is dependent on the energy and the type of the primary particle, and may vary for different biological endpoints. To investigate "biological Bragg curves", we analyzed micronuclei (MN) induction along the particle traversal of Si and Fe ions at incident energies of 300 MeV/nucleon and 1 GeV/nucleon. A quantitative biological response curve did not reveal an increased yield of MN at the location of the Bragg peak. However, the ratio of mono-to bi-nucleated cells, which indicates inhibition in cell progression, increased at the Bragg peak location. These results confirm the hypothesis that "over kill" at the Bragg peak will affect the outcome of other biological endpoints.

Separation, preconcentration and inductively coupled plasma-mass spectrometric (ICP-MS) determination of thorium(IV), titanium(IV), iron(III), lead(II) and chromium(III) on 2-nitroso-1-naphthol impregnated MCI GEL CHP20P resin.

PubMed

Aydin, Funda Armagan; Soylak, Mustafa

2010-01-15

A simple and effective method is presented for the separation and preconcentration of Th(IV), Ti(IV), Fe(III), Pb(II) and Cr(III) by solid phase extraction on 2-nitroso-1-naphthol impregnated MCI GEL CHP20P resin prior to their inductively coupled plasma-mass spectrometric determinations. The influence of analytical parameters including pH of the aqueous solution, flow rates of sample and eluent solutions and sample volume on the quantitative recoveries of analyte ions was investigated. Matrix effects caused by the presence of alkali, earth alkali and some metal ions in the analyzed solutions were investigated. The presented solid phase extraction method was applied to BCR-144R Sewage Sludge (domestic origin), BCR-141R Calcareous Loam Soil, NIST 1568a Rice Flour and NIST 1577b Bovine Liver certified reference materials (CRMs) for the determination of analyte ions and the results were in good agreement with the certified values. The separation procedure presented was also applied to the various natural water samples collected from Turkey with satisfactory results.

A study of increasing radical density and etch rate using remote plasma generator system

NASA Astrophysics Data System (ADS)

Lee, Jaewon; Kim, Kyunghyun; Cho, Sung-Won; Chung, Chin-Wook

2013-09-01

To improve radical density without changing electron temperature, remote plasma generator (RPG) is applied. Multistep dissociation of the polyatomic molecule was performed using RPG system. RPG is installed to inductively coupled type processing reactor; electrons, positive ions, radicals and polyatomic molecule generated in RPG and they diffused to processing reactor. The processing reactor dissociates the polyatomic molecules with inductively coupled power. The polyatomic molecules are dissociated by the processing reactor that is operated by inductively coupled power. Therefore, the multistep dissociation system generates more radicals than single-step system. The RPG was composed with two cylinder type inductively coupled plasma (ICP) using 400 kHz RF power and nitrogen gas. The processing reactor composed with two turn antenna with 13.56 MHz RF power. Plasma density, electron temperature and radical density were measured with electrical probe and optical methods.

Mutagenic effect of accelerated heavy ions on bacterial cells

NASA Astrophysics Data System (ADS)

Boreyko, A. V.; Krasavin, E. A.

2011-11-01

The heavy ion accelerators of the Joint Institute for Nuclear Research were used to study the regularities and mechanisms of formation of different types of mutations in prokaryote cells. The induction of direct (lac-, ton B-, col B) mutations for Esherichia coli cells and reverse his- → His+ mutations of Salmonella typhimurium, Bacillus subtilis cells under the action of radiation in a wide range of linear energy transfer (LET) was studied. The regularities of formation of gene and structural (tonB trp-) mutations for Esherichia coli bacteria under the action of accelerated heavy ions were studied. It was demonstrated that the rate of gene mutations as a function of the dose under the action of Γ rays and accelerated heavy ions is described by linear-quadratic functions. For structural mutations, linear "dose-effect" dependences are typical. The quadratic character of mutagenesis dose curves is determined by the "interaction" of two independent "hitting" events in the course of SOS repair of genetic structures. The conclusion made was that gene mutations under the action of accelerated heavy ions are induced by δ electron regions of charged particle tracks. The methods of SOS chromotest, SOS lux test, and λ prophage induction were used to study the regularities of SOS response of cells under the action of radiations in a wide LET range. The following proposition was substantiated: the molecular basis for formation of gene mutations are cluster single-strand DNA breaks, and that for structural mutations, double-strand DNA breaks. It was found out that the LET dependence of the relative biological efficiency of accelerated ions is described by curves with a local maximum. It was demonstrated that the biological efficiency of ionizing radiations with different physical characteristics on cells with different genotype, estimated by the lethal action, induction of gene and deletion mutations, precision excision of transposons, is determined by the specific features of energy transfer of the radiations that affect the character of induced DNA damage, and the efficiency inducible and constitutive cell repair systems. The growth of relative biological efficiency of heavy charged particles is determined by the growth of the damage yield of the DNA participating in the formation of radiation-induced effects, and higher efficiency of inducible repair systems. It was established that the LET value ( L max) for which the maximum (according to the applied irradiation criteria) coefficients of relative biological efficiency are observed varies depending on the character of the registered radiation induced effect. It was demonstrated that for gene mutations and induction of precision excision of mobile elements the values of L max are realized in a LET range of ≈20 keV/μm. For lethal effects of irradiation and induction of deletion mutations the value of L max is ≈ 100 and 50 keV/μm, respectively. The differences in the L max for the studied radiation gene effectis are determined by the different type of DNA damage participating in the mutation process. A molecular model of the formation of gene mutations in Escherichia coli cells under the action of ionizing radiation was proposed. Basic DNA radiation damage and main repair ways were considered in the framework of this model. The basis is the idea of the decisive role of mutagenic, error-prone, branch of SOS repair in fixing premutation DNA damage into point mutations. It was demonstrated that the central mechanism in this process is the formation of an inducible multi-enzymatic complex including the DNA polymerase V (Umu C), RecA-protease, SSB proteins, subunits of DNA polymerase III, performing erroneous DNA synthesis on the damaged matrix. A mathematical model of induction of gene mutations under ultraviolet cell irradiation was developed based on the molecular model.

Production characteristics and body composition of juvenile cobia fed three different commercial diets in recirculating aquaculture systems

USDA-ARS?s Scientific Manuscript database

The effect of feeding three commercial diets on production characteristics and body composition of juvenile cobia Rachycentron canadum reared using recirculating aquaculture systems (RAS) was evaluated in a 56 d growth trial. Juvenile cobia (29.2 +/= 0.7 g, mean weight +/= SE) were stocked into thr...

Stocking density effects on production characteristics and body composition of market size cobia, Rachycentron canadum, reared in recirculating aquaculture systems

USDA-ARS?s Scientific Manuscript database

Production density in excess of a critical threshold can result in a negative relationship between stocking density and fish production. This study was conducted to evaluate production characteristics of juvenile cobia Rachycentron canadum, reared to market size in production-scale recirculating aq...

Assessing peracetic acid as a means to control post-vaccination Saprolegniasis in Atlantic salmon Salmo salar parr in recirculation aquaculture systems

USDA-ARS?s Scientific Manuscript database

Land-based closed containment facilities, utilizing recirculation aquaculture system (RAS) technologies, can reduce or eliminate the introduction of obligate fish pathogens. Regardless, the presence of opportunistic pathogens must be assumed, and these agents can cause disease during unfavorable con...

Abnormal swimming behavior and increased deformities in rainbow trout Oncorhynchus mykiss cultured in low exchange water recirculation aquaculture systems

USDA-ARS?s Scientific Manuscript database

Two studies were conducted to determine if accumulating water quality parameters would negatively impact rainbow trout Oncorhynchus mykiss health and welfare within water recirculation aquaculture systems (WRAS) that were operated at low and near-zero water exchange, with and without ozonation, and ...

Systemic granuloma observed in Atlantic salmon Salmo salar raised to market size in a freshwater recirculation aquaculture system

USDA-ARS?s Scientific Manuscript database

Systemic granuloma was observed in sampled adult Atlantic salmon Salmo salar raised to harvest size in a freshwater recirculation aquaculture system. The prevalence of this condition was estimated at 10-20% of the population, with affected individuals grossly demonstrating pathology in varying degre...

Effects of semi-continous peracetic acid dosing on rainbow trout Oncorhynchus mykiss performance, water quality, and off-flavor compounds in recirculation aquaculture systems

USDA-ARS?s Scientific Manuscript database

Water clarifying and disinfection techniques such as ozonation and ultraviolet irradiation are commonly used in recirculation aquaculture systems (RAS); however, the capital and operating costs of these technologies are expensive. Cost-effective treatment options that maintain fish health and simult...

Researchers evaluate low-energy recirculating system for inland production of marine finfish juveniles

USDA-ARS?s Scientific Manuscript database

The low-energy recirculating aquaculture system consists of nine separate modules which utilize the double drain fish culture tank paired to a moving bed biofilter. The nine fiberglass tanks are five feet in diameter and normal water depth is about three feet for a total tank volume of approximately...

Temperature effects on biomass, geosmin, and 2-methylisoborneol production and cellular activity by Nocardia spp. and Streptomyces spp. isolated from rainbow trout recirculating aquaculture systems

USDA-ARS?s Scientific Manuscript database

Isolates of Nocardia cummidelens, Nocardia fluminea, Streptomyces albidoflavus, and Streptomyces luridiscabiei attributing to geosmin-related off-flavor in rainbow trout (Oncorhynchus mykiss) raised in recirculating aquaculture systems (RAS) were evaluated for the effect of temperature (10-30 degree...

The study of recirculating aquaculture system in pond and its purification effect

NASA Astrophysics Data System (ADS)

Qu, Jiangqi; Zhang, Qingjing; Jia, Chengxia; Liu, Pan; Yang, Mu

2017-05-01

In this paper, a recirculating aquaculture purification system (RAPS) was designed to solve the problems of aquaculture pollution and shortage of freshwater resource according to the characteristic of northern freshwater ponds of China. The system were arranged in series and composed of high density culture pond, deposit pond, floating and submerged plant pond, ecological floating bed pond and biofilm filtrate pond. At the fish density of 20~30kg/m3 in the high density culture pond, the water quality parameters were monitored seasonally. The results indicated that the removal rate of total nitrogen, total phosphorus, ammonia nitrogen and nitrite nitrogen in the recirculating aquaculture system were 69.59%, 77.89%, 72.54% and 68.68%, respectively. The floating and submerged plant pond and ecological floating bed pond can remove TN and TP obviously, and increase dissolved oxygen and transparency significantly. And the biofilm filtrate pond has good effect of removing ammonium nitrogen and nitrite nitrogen, meanwhile, the microbial communities in the recirculating aquaculture system regulate on the water quality. Therefore, the RAPS show significant effects on water saving and pollution emission reducing.

Recirculation or artificial aeration in vertical flow constructed wetlands: a comparative study for treating high load wastewater.

PubMed

Foladori, Paola; Ruaben, Jenny; Ortigara, Angela R C

2013-12-01

Vertical subsurface-flow constructed wetlands at pilot-scale have been applied to treat high hydraulic and organic loads by implementing the following configurations: (1) intermittent recirculation of the treated wastewater from the bottom to the top of the bed, (2) intermittent artificial aeration supplied at the bottom of the bed and (3) the combination of both. These configurations were operated with a saturated bottom layer for a 6h-treatment phase, followed by a free drainage phase prior to a new feeding. COD removal efficiency was 85-90% in all the configurations and removed loads were 54-70 gCOD m(-2)d(-1). The aerated and recirculated wetland resulted in a higher total nitrogen removal (8.6 gN m(-2)d(-1)) due to simultaneous nitrification/denitrification, even in the presence of intermittent aeration (6.8 Nm(3)m(-2)d(-1)). The extra investment needed for implementing aeration/recirculation would be compensated for by a reduction of the surface area per population equivalent, which decreased to 1.5m(2)/PE. Copyright © 2013 Elsevier Ltd. All rights reserved.

Hydrodynamic and chemical effects of hydrogen dilution on soot evolution in turbulent nonpremixed bluff body ethylene flames

NASA Astrophysics Data System (ADS)

Deng, Sili; Mueller, Michael E.; Chan, Qing N.; Qamar, Nader H.; Dally, Bassam B.; Alwahabi, Zeyad T.; Nathan, Graham J.

2015-11-01

A turbulent nonpremixed bluff body ethylene/hydrogen (volume ratio 2:1) flame is studied and compared with the ethylene counterpart [Mueller et al., Combust. Flame, 160, 2013]. Similar to the ethylene buff body flame, a low-strain recirculation zone, a high-strain neck region, and a downstream jet-like region are observed. However, the maximum soot volume fraction in the recirculation zone of the hydrogen diluted case is significantly lower than the ethylene case. Large Eddy Simulation is used to further investigate soot evolution in the recirculation zone and to elucidate the role of hydrogen dilution. Since the central jet Reynolds numbers in both cases are the same (approximately 30,900), the jet velocity of the hydrogen diluted case is higher, resulting in a shorter and leaner recirculation zone. In addition, hydrogen dilution chemically suppresses soot formation due to the reduction of C/H ratio. Consequently, the reduction of the soot volume fraction for the hydrogen diluted ethylene flame is attributed to two major effects: hydrodynamic and chemical effects.

Contribution of 3-D time-lapse ERT to the study of leachate recirculation in a landfill

DOE Office of Scientific and Technical Information (OSTI.GOV)

Clement, R., E-mail: remi.clement@hmg.inpg.fr; Grenoble Universite, B.P. 53, 38041 Grenoble Cedex 9; Oxarango, L.

2011-03-15

Leachate recirculation is a key process in the operation of municipal waste landfills as bioreactors. It aims at increasing the moisture content to optimise the biodegradation. Because waste is a very heterogeneous and anisotropic porous media, the geometry of the leachate plume recirculation is difficult to delineate from the surface at the scale of the bioreactor site. In this study, 3-D time-lapse electrical resistivity tomography (ERT) was used to obtain useful information for understanding leachate recirculation hydrodynamics. The ERT inversion methodology and the electrode arrays were optimised using numerical modelling simulating a 3-D leachate injection scenario. Time-lapse ERT was subsequentlymore » applied at the field scale during an experimental injection. We compared ERT images with injected volumes to evaluate the sensitivity of time-lapse ERT to delineate the plume migration. The results show that time-lapse ERT can accomplish the following: (i) accurately locate the injection plume, delineating its depth and lateral extension; (ii) be used to estimate some hydraulic properties of waste.« less

Turbulence characteristics of swirling flowfields. Ph.D. Thesis. Final Report

NASA Technical Reports Server (NTRS)

Jackson, T. W.; Lilley, D. G.

1985-01-01

The time mean and turbulence properties of a confined swirling jet using the six orientation, single hot wire technique were obtained. The effect of swirl on a confined, expanding jet is to reduce the size of the corner recirculation zone and generate a central recirculation zone followed by a precessing vortex core. The effect of introducing a contraction nozzle of area ratio four, located two test section diameters downstream of the inlet, is to dramatically reduce the size and shape of the central recirculation zone for the swirling flows considered. The shear stresses are found to increase by an order of magnitude in the region of the contraction nozzle because of large radial gradients of axial velocity. Reduction of the expansion ratio to D/o = 1 causes the time mean flow field to be homogeneous throughout the entire test section with the tangential velocity dominating in the swirling cases. No recirculation zones were observed for these particular flows. Turbulence levels and dissipation rates were found to be low except in the entrance regions and in areas of acceleration in the swirling flow cases.

Five-hole pitot probe time-mean velocity measurements in confined swirling flows

NASA Technical Reports Server (NTRS)

Yoon, H. K.; Lilley, D. G.

1983-01-01

Nonswirling and swirling nonreacting flows in an axisymmetric test section with an expansion ratio D/d = 2, which may be equipped with contraction nozzles of area ratios 2 and 4, are investigated. The effects of a number of geometric parameters on the flow-field are investigated, among them side-wall expansion angles of 90 and 45 deg, swirl vane angles of 0, 38, 45, 60, and 70 deg, and contraction nozzle locations L/D = 1 and 2 (if present). Data are acquired by means of a five-hole pitot probe enabling three time-mean velocity components in the axial, radial, and azimuthal directions to be measured. The velocities are extensively plotted and artistic impressions of recirculation zones are set forth. The presence of a swirler is found to shorten the corner recirculation zone and to generate a central recirculation zone followed by a precessing vortex core. A gradual inlet expansion has the effect of encouraging the flow to remain close to the sidewall and shortening the extent of the corner recirculation zone in all cases investigated.

Non-Targeted Effects and the Dose Response for Heavy Ion Tumorigenesis

NASA Technical Reports Server (NTRS)

Chappelli, Lori J.; Cucinotta, Francis A.

2010-01-01

BACKGROUND: There is no human epidemiology data available to estimate the heavy ion cancer risks experienced by astronauts in space. Studies of tumor induction in mice are a necessary step to estimate risks to astronauts. Previous experimental data can be better utilized to model dose response for heavy ion tumorigenesis and plan future low dose studies. DOSE RESPONSE MODELS: The Harderian Gland data of Alpen et al.[1-3] was re-analyzed [4] using non-linear least square regression. The data set measured the induction of Harderian gland tumors in mice by high-energy protons, helium, neon, iron, niobium and lanthanum with LET s ranging from 0.4 to 950 keV/micron. We were able to strengthen the individual ion models by combining data for all ions into a model that relates both radiation dose and LET for the ion to tumor prevalence. We compared models based on Targeted Effects (TE) to one motivated by Non-targeted Effects (NTE) that included a bystander term that increased tumor induction at low doses non-linearly. When comparing fitted models to the experimental data, we considered the adjusted R2, the Akaike Information Criteria (AIC), and the Bayesian Information Criteria (BIC) to test for Goodness of fit.In the adjusted R2test, the model with the highest R2values provides a better fit to the available data. In the AIC and BIC tests, the model with the smaller values of the summary value provides the better fit. The non-linear NTE models fit the combined data better than the TE models that are linear at low doses. We evaluated the differences in the relative biological effectiveness (RBE) and found the NTE model provides a higher RBE at low dose compared to the TE model. POWER ANALYSIS: The final NTE model estimates were used to simulate example data to consider the design of new experiments to detect NTE at low dose for validation. Power and sample sizes were calculated for a variety of radiation qualities including some not considered in the Harderian Gland data set and with different background tumor incidences. We considered different experimental designs with varying number of doses and varying low doses dependant on the LET of the radiation. The optimal design to detect a NTE for an individual ion had 4 doses equally spaced below a maximal dose where bending due to cell sterilization was < 2%. For example at 100 keV/micron we would irradiate at 0.03 Gy, 0.065 Gy, 0.13 Gy, and 0.26 Gy and require 850 mice including a control dose for a sensitivity to detect NTE with 80% power. Sample sizes could be improved by combining ions similar to the methods used with the Harderian Gland data.

Delayed expression of hpS2 and prolonged expression of CIP1/WAF1/SDI1 in human tumour cells irradiated with X-rays, fission neutrons or 1 GeV/nucleon Fe ions

NASA Technical Reports Server (NTRS)

Balcer-Kubiczek, E. K.; Zhang, X. F.; Harrison, G. H.; Zhou, X. J.; Vigneulle, R. M.; Ove, R.; McCready, W. A.; Xu, J. F.

1999-01-01

PURPOSE: Differences in gene expression underlie the phenotypic differences between irradiated and unirradiated cells. The goal was to identify late-transcribed genes following irradiations differing in quality, and to determine the RBE of 1 GeV/n Fe ions. MATERIALS AND METHODS: Clonogenic assay was used to determine the RBE of Fe ions. Differential hybridization to cDNA target clones was used to detect differences in expression of corresponding genes in mRNA samples isolated from MCF7 cells irradiated with iso-survival doses of Fe ions (0 or 2.5 Gy) or fission neutrons (0 or 1.2 Gy) 7 days earlier. Northern analysis was used to confirm differential expression of cDNA-specific mRNA and to examine expression kinetics up to 2 weeks after irradiation. RESULTS: Fe ion RBE values were between 2.2 and 2.6 in the lines examined. Two of 17 differentially expressed cDNA clones were characterized. hpS2 mRNA was elevated from 1 to 14 days after irradiation, whereas CIP1/WAF1/SDI1 remained elevated from 3 h to 14 days after irradiation. Induction of hpS2 mRNA by irradiation was independent of p53, whereas induction of CIP1/WAF1/SDI1 was observed only in wild-type p53 lines. CONCLUSIONS: A set of coordinately regulated genes, some of which are independent of p53, is associated with change in gene expression during the first 2 weeks post-irradiation.

Fourier transform C-13 NMR analysis of some free and potassium-ion complexed antibiotics.

NASA Technical Reports Server (NTRS)

Ohnishi, M.; Fedarko, M.-C.; Baldeschwieler, J. D.; Johnson, L. F.

1972-01-01

Fourier transforms of the noise-decoupled, natural abundance C-13 NMR free induction decays of the cyclic antibiotic valinomycin and its potassium-ion complex have been obtained at 25.2 MHz. Comparisons are made with C-13 NMR spectra taken at 22.6 MHz of the cyclic antibiotic nonactin and the synthetic polyether dicyclohexyl-18-crown-6 and their potassium complexes. The results obtained suggest that conformational rearrangements of the molecule as a whole can compete with direct interactions between carbons and the potassium ion in determining C-13 chemical shift differences between the free and complexed species.

Building America Case Study: Control Retrofits for Multifamily Domestic Hot Water Recirculation Systems, Brooklyn, New York

DOE Office of Scientific and Technical Information (OSTI.GOV)

Domestic hot water (DHW) heating is the second largest energy end use in U.S. buildings, exceeded only by space conditioning. Recirculation systems consisting of a pump and piping loop(s) are commonly used in multifamily buildings to reduce wait time for hot water at faucets; however, constant pumping increases energy consumption by exposing supply and return line piping to continuous heat loss, even during periods when there is no demand for hot water. In this study, ARIES installed and tested two types of recirculation controls in a pair of buildings in order to evaluate their energy savings potential. Demand control, temperaturemore » modulation controls, and the simultaneous operation of both were compared to the baseline case of constant recirculation. Additionally, interactive effects between DHW control fuel reductions and space conditioning (heating and cooling) were estimated in order to make more realistic predictions of the payback and financial viability of retrofitting DHW systems with these controls. Results showed that DHW fuel consumption reduced by 7 percent after implementing the demand control technique, 2 percent after implementing temperature modulation, and 15 percent after implementing demand control and temperature modulation techniques simultaneously; recirculation pump runtime was reduced to 14 minutes or less per day. With space heating and cooling interactions included, the estimated annual cost savings were 8 percent, 1 percent, and 14 percent for the respective control techniques. Possible complications in the installation, commissioning and operation of the controls were identified and solutions offered.« less

Building America Case Study: Control Retrofits for Multifamily Domestic Hot Water Recirculation Systems, Brooklyn, New York

DOE Office of Scientific and Technical Information (OSTI.GOV)

J. Dentz; E. Ansanelli, H. Henderson, Jr.; K. Varshney

Domestic hot water (DHW) heating is the second largest energy end use in U.S. buildings, exceeded only by space conditioning. Recirculation systems consisting of a pump and piping loop(s) are commonly used in multifamily buildings to reduce wait time for hot water at faucets; however, constant pumping increases energy consumption by exposing supply and return line piping to continuous heat loss, even during periods when there is no demand for hot water. In this study, ARIES installed and tested two types of recirculation controls in a pair of buildings in order to evaluate their energy savings potential. Demand control, temperaturemore » modulation controls, and the simultaneous operation of both were compared to the baseline case of constant recirculation. Additionally, interactive effects between DHW control fuel reductions and space conditioning (heating and cooling) were estimated in order to make more realistic predictions of the payback and financial viability of retrofitting DHW systems with these controls. Results showed that DHW fuel consumption reduced by 7% after implementing the demand control technique, 2% after implementing temperature modulation, and 15% after implementing demand control and temperature modulation techniques simultaneously; recirculation pump runtime was reduced to 14 minutes or less per day. With space heating and cooling interactions included, the estimated annual cost savings were 8%, 1%, and 14% for the respective control techniques. Possible complications in the installation, commissioning and operation of the controls were identified and solutions offered.« less

Pilot-scale experiment on anaerobic bioreactor landfills in China.

PubMed

Jiang, Jianguo; Yang, Guodong; Deng, Zhou; Huang, Yunfeng; Huang, Zhonglin; Feng, Xiangming; Zhou, Shengyong; Zhang, Chaoping

2007-01-01

Developing countries have begun to investigate bioreactor landfills for municipal solid waste management. This paper describes the impacts of leachate recirculation and recirculation loadings on waste stabilization, landfill gas (LFG) generation and leachate characteristics. Four simulated anaerobic columns, R1-R4, were each filled with about 30 tons of waste and recirculated weekly with 1.6, 0.8 and 0.2m(3) leachate and 0.1m(3) tap water. The results indicated that the chemical oxygen demand (COD) half-time of leachate from R1 was about 180 days, which was 8-14 weeks shorter than that of R2-R4. A large amount of LFG was first produced in R1, and its generation rate was positively correlated to the COD or volatile fatty acid concentrations of influent leachates after the 30th week. By the 50th week of recirculation, the waste in R1 was more stabilized, with 931.2 kg COD or 175.6 kg total organic carbon released and with the highest landfill gas production. However, this contributed mainly to washout by leachate, which also resulted in the reduction of LFG generation potential and accumulation of ammonia and/or phosphorus in the early stage. Therefore, the regimes of leachate recirculation should be adjusted to the phases of waste stabilization to enhance efficiency of energy recovery. Integrated with the strategy of in situ leachate management, extra pre-treatment or post-treatment methods to remove the nutrients are recommended.

Production of Tuber-Inducing Factor

NASA Technical Reports Server (NTRS)

Stutte, Gary W.; Yorio, Neil C.

2006-01-01

A process for making a substance that regulates the growth of potatoes and some other economically important plants has been developed. The process also yields an economically important by-product: potatoes. The particular growth-regulating substance, denoted tuber-inducing factor (TIF), is made naturally by, and acts naturally on, potato plants. The primary effects of TIF on potato plants are reducing the lengths of the main shoots, reducing the numbers of nodes on the main stems, reducing the total biomass, accelerating the initiation of potatoes, and increasing the edible fraction (potatoes) of the overall biomass. To some extent, these effects of TIF can override environmental effects that typically inhibit the formation of tubers. TIF can be used in the potato industry to reduce growth time and increase harvest efficiency. Other plants that have been observed to be affected by TIF include tomatoes, peppers, radishes, eggplants, marigolds, and morning glories. In the present process, potatoes are grown with their roots and stolons immersed in a nutrient solution in a recirculating hydroponic system. From time to time, a nutrient replenishment solution is added to the recirculating nutrient solution to maintain the required nutrient concentration, water is added to replace water lost from the recirculating solution through transpiration, and an acid or base is added, as needed, to maintain the recirculating solution at a desired pH level. The growing potato plants secrete TIF into the recirculating solution. The concentration of TIF in the solution gradually increases to a range in which the TIF regulates the growth of the plants.

Production of polycaprolactone nanoparticles with low polydispersity index in a tubular recirculating system by using a multifactorial design of experiments

NASA Astrophysics Data System (ADS)

Colmenares Roldán, Gabriel Jaime; Agudelo Gomez, Liliana María; Carlos Cornelio, Jesús Antonio; Rodriguez, Luis Fernando; Pinal, Rodolfo; Hoyos Palacio, Lina Marcela

2018-03-01

Encapsulation and controlled release of substances using polymeric nanoparticles require that these have a high reproducibility, homogeneity, and control over their properties (diameter and polydispersity), especially when they are to be used in medical, pharmaceutical, or nutritional applications among others. In conventional production systems, it is tough to ensure these characteristics; hence, the cost increases when we try to control these properties. This paper shows a comparison between a recirculating system and the standard nanoprecipitation technique for producing polymeric nanoparticles. In previous investigations, we evaluate the effect of recirculating flow and the ratio between the organic and aqueous phase. For this paper, we evaluated the effect of polymer and surfactant concentrations using a multifactorial design of experiments on the recirculating system and on the standard nanoprecipitation system. The response of the design was the average diameter of the nanoparticles and polydispersity index. Finally, we found that the polymer and surfactant concentrations could change the average diameter and polydispersity index of the nanoparticles obtained. On the other hand, it was found that the effect of the polymer concentration was stronger than the surfactant concentration to reduce the average diameter of the nanoparticles. The results of the present study show that the proposed recirculation system presents a high potential to produce polymer nanoparticles with good morphological characteristics, particle size distributions in the nano range, and with a low polydispersity. The average mean size of nanoparticles of polycaprolactone for the design using the recirculating system was of 61 to 140 nm and the values of polydispersity index PDI for this design were between 0.097 and 0.22, while for the design using the standard nanoprecipitation technique, the obtained diameters were 74 to 176 nm and the polydispersity was between 0.26 and 0.41.

Effect of high-pressure homogenization preparation on mean globule size and large-diameter tail of oil-in-water injectable emulsions.

PubMed

Peng, Jie; Dong, Wu-Jun; Li, Ling; Xu, Jia-Ming; Jin, Du-Jia; Xia, Xue-Jun; Liu, Yu-Ling

2015-12-01

The effect of different high pressure homogenization energy input parameters on mean diameter droplet size (MDS) and droplets with > 5 μm of lipid injectable emulsions were evaluated. All emulsions were prepared at different water bath temperatures or at different rotation speeds and rotor-stator system times, and using different homogenization pressures and numbers of high-pressure system recirculations. The MDS and polydispersity index (PI) value of the emulsions were determined using the dynamic light scattering (DLS) method, and large-diameter tail assessments were performed using the light-obscuration/single particle optical sensing (LO/SPOS) method. Using 1000 bar homogenization pressure and seven recirculations, the energy input parameters related to the rotor-stator system will not have an effect on the final particle size results. When rotor-stator system energy input parameters are fixed, homogenization pressure and recirculation will affect mean particle size and large diameter droplet. Particle size will decrease with increasing homogenization pressure from 400 bar to 1300 bar when homogenization recirculation is fixed; when the homogenization pressure is fixed at 1000 bar, the particle size of both MDS and percent of fat droplets exceeding 5 μm (PFAT 5 ) will decrease with increasing homogenization recirculations, MDS dropped to 173 nm after five cycles and maintained this level, volume-weighted PFAT 5 will drop to 0.038% after three cycles, so the "plateau" of MDS will come up later than that of PFAT 5 , and the optimal particle size is produced when both of them remained at plateau. Excess homogenization recirculation such as nine times under the 1000 bar may lead to PFAT 5 increase to 0.060% rather than a decrease; therefore, the high-pressure homogenization procedure is the key factor affecting the particle size distribution of emulsions. Varying storage conditions (4-25°C) also influenced particle size, especially the PFAT 5 . Copyright © 2015. Published by Elsevier B.V.

Microfiltration: Effect of retentate protein concentration on limiting flux and serum protein removal with 4-mm-channel ceramic microfiltration membranes.

PubMed

Hurt, E E; Adams, M C; Barbano, D M

2015-04-01

The objective of our study was to determine if the limiting flux and serum protein (SP) removal were different at 8, 9, or 10% true protein (TP) in the microfiltration (MF) retentate recirculation loop using 0.1-µm ceramic graded permeability membranes with 4-mm-channel diameters operated at 50 °C using a diluted milk protein concentrate with 85% protein on a total solids basis (MPC85) as the MF feed. The limiting flux for the MF of diluted MPC85 was determined at 3 TP concentrations in the recirculation loop (8, 9, and 10%). The experiment was replicated 3 times for a total of 9 runs. On the morning of each run, MPC85 was diluted with reverse osmosis water to an MF feed TP concentration of 5.4%. In all runs, the starting flux was 55 kg/m(2) per hour, the flux was increased in steps until the limiting flux was reached. The minimum flux increase was 10 kg/m(2) per hour. The limiting flux decreased as TP concentration in the recirculation loop increased. The limiting flux was 154 ± 0.3, 133 ± 0.7, and 117 ± 3.3 kg/m(2) per hour at recirculation loop TP concentrations of 8.2 ± 0.07, 9.2 ± 0.04, and 10.2 ± 0.09%, respectively. No effect of recirculation loop TP concentration on the SP removal factor was detected. However, the SP removal factor decreased from 0.80 ± 0.02 to 0.75 ± 0.02 as flux was increased from the starting flux of 55 kg/m(2) per hour to the limiting flux, with a similar decrease seen at all recirculation loop TP concentrations. Copyright © 2015 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Genetic Analysis of T Cell Lymphomas in Carbon Ion-Irradiated Mice Reveals Frequent Interstitial Chromosome Deletions: Implications for Second Cancer Induction in Normal Tissues during Carbon Ion Radiotherapy.

PubMed

Blyth, Benjamin J; Kakinuma, Shizuko; Sunaoshi, Masaaki; Amasaki, Yoshiko; Hirano-Sakairi, Shinobu; Ogawa, Kanae; Shirakami, Ayana; Shang, Yi; Tsuruoka, Chizuru; Nishimura, Mayumi; Shimada, Yoshiya

2015-01-01

Monitoring mice exposed to carbon ion radiotherapy provides an indirect method to evaluate the potential for second cancer induction in normal tissues outside the radiotherapy target volume, since such estimates are not yet possible from historical patient data. Here, male and female B6C3F1 mice were given single or fractionated whole-body exposure(s) to a monoenergetic carbon ion radiotherapy beam at the Heavy Ion Medical Accelerator in Chiba, Japan, matching the radiation quality delivered to the normal tissue ahead of the tumour volume (average linear energy transfer = 13 keV x μm(-1)) during patient radiotherapy protocols. The mice were monitored for the remainder of their lifespan, and a large number of T cell lymphomas that arose in these mice were analysed alongside those arising following an equivalent dose of 137Cs gamma ray-irradiation. Using genome-wide DNA copy number analysis to identify genomic loci involved in radiation-induced lymphomagenesis and subsequent detailed analysis of Notch1, Ikzf1, Pten, Trp53 and Bcl11b genes, we compared the genetic profile of the carbon ion- and gamma ray-induced tumours. The canonical set of genes previously associated with radiation-induced T cell lymphoma was identified in both radiation groups. While the pattern of disruption of the various pathways was somewhat different between the radiation types, most notably Pten mutation frequency and loss of heterozygosity flanking Bcl11b, the most striking finding was the observation of large interstitial deletions at various sites across the genome in carbon ion-induced tumours, which were only seen infrequently in the gamma ray-induced tumours analysed. If such large interstitial chromosomal deletions are a characteristic lesion of carbon ion irradiation, even when using the low linear energy transfer radiation to which normal tissues are exposed in radiotherapy patients, understanding the dose-response and tissue specificity of such DNA damage could prove key to assessing second cancer risk in carbon ion radiotherapy patients.

Noninductively Driven Tokamak Plasmas at Near-Unity Toroidal Beta

DOE PAGES

Schlossberg, David J.; Bodner, Grant M.; Bongard, Michael W.; ...

2017-07-01

Access to and characterization of sustained, toroidally confined plasmas with a very high plasma-to-magnetic pressure ratio (β t), low internal inductance, high elongation, and nonsolenoidal current drive is a central goal of present tokamak plasma research. Stable access to this desirable parameter space is demonstrated in plasmas with ultralow aspect ratio and high elongation. Local helicity injection provides nonsolenoidal sustainment, low internal inductance, and ion heating. Equilibrium analyses indicate β t up to ~100% with a minimum |B| well spanning up to ~50% of the plasma volume.

Noninductively Driven Tokamak Plasmas at Near-Unity Toroidal Beta.

PubMed

Schlossberg, D J; Bodner, G M; Bongard, M W; Burke, M G; Fonck, R J; Perry, J M; Reusch, J A

2017-07-21

Access to and characterization of sustained, toroidally confined plasmas with a very high plasma-to-magnetic pressure ratio (β_{t}), low internal inductance, high elongation, and nonsolenoidal current drive is a central goal of present tokamak plasma research. Stable access to this desirable parameter space is demonstrated in plasmas with ultralow aspect ratio and high elongation. Local helicity injection provides nonsolenoidal sustainment, low internal inductance, and ion heating. Equilibrium analyses indicate β_{t} up to ∼100% with a minimum |B| well spanning up to ∼50% of the plasma volume.

Control Infrastructure for a Pulsed Ion Accelerator

NASA Astrophysics Data System (ADS)

Persaud, A.; Regis, M. J.; Stettler, M. W.; Vytla, V. K.

2016-10-01

We report on updates to the accelerator controls for the Neutralized Drift Compression Experiment II, a pulsed induction-type accelerator for heavy ions. The control infrastructure is built around a LabVIEW interface combined with an Apache Cassandra backend for data archiving. Recent upgrades added the storing and retrieving of device settings into the database, as well as ZeroMQ as a message broker that replaces LabVIEW's shared variables. Converting to ZeroMQ also allows easy access via other programming languages, such as Python.

Control Infrastructure for a Pulsed Ion Accelerator

DOE PAGES

Persaud, A.; Regis, M. J.; Stettler, M. W.; ...

2016-07-27

We report on updates to the accelerator controls for the Neutralized Drift Compression Experiment II, a pulsed induction-type accelerator for heavy ions. The control infrastructure is built around a LabVIEW interface combined with an Apache Cassandra backend for data archiving. Recent upgrades added the storing and retrieving of device settings into the database, as well as ZeroMQ as a message broker that replaces LabVIEW's shared variables. Converting to ZeroMQ also allows easy access via other programming languages, such as Python.

Techniques for correcting velocity and density fluctuations of ion beams in ion inducti on accelerators

NASA Astrophysics Data System (ADS)

Woo, K. M.; Yu, S. S.; Barnard, J. J.

2013-06-01

It is well known that the imperfection of pulse power sources that drive the linear induction accelerators can lead to time-varying fluctuation in the accelerating voltages, which in turn leads to longitudinal emittance growth. We show that this source of emittance growth is correctable, even in space-charge dominated beams with significant transients induced by space-charge waves. Two correction methods are proposed, and their efficacy in reducing longitudinal emittance is demonstrated with three-dimensional particle-in-cell simulations.

ONR Tokyo Scientific Bulletin. Volume 5, Number 2 April - June 1980.

DTIC Science & Technology

1980-06-01

magnetic acoustic wave and a direct measurment of the electron density can allow one to determine the density of two kinds of ions, or of one ion and one...aerial photos can be ordered. Digital data on landforms, soil, rivers, and land use, among others aeavailable from magnetic tape. GSI has been...25 watts from a single device. Source lead inductance is minimized by completely metalizing the periphery and sides of the chip to provide a ground

The last large pelletron accelerator of the Herb era

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chopra, S.; Narayanan, M. M.; Joshi, R.

1999-04-26

Prof. Ray Herb pioneered the concept and design of the tandem Pelletron accelerator in the late sixties at NEC. The 15UD Pelletron at Nuclear Science Centre (NSC), upgraded for 16MV operation using compressed geometry accelerating tubes is the last such large Pelletron. It has unique features like offset and matching quadrupoles after the stripper for charge state selection inside the high voltage terminal and consequently the option of further stripping the ion species of the selected charge states at high energy dead section, and elaborate pulsing system in the pre-acceleration region consisting of a beam chopper, a travelling wave deflector,more » a light ion buncher (1-80 amu) and a heavy ion buncher (>80 amu). NSC was established as a heavy ion accelerator based inter university centre in 1985. It became operational in July 1991 to cater to the research requirements of a large user community which at present includes about fifty universities, twenty-eight colleges and a dozen other academic institutes and research laboratories. The number of users in Materials and allied sciences is about 500. Various important modifications have been made to improve the performance of the accelerator in the last seven years. These include replacement of the corona voltage grading system by a resistor based one, a pick-up loop to monitor charging system performance, conversion from basic double unit structure to singlet, installation of a spiral cavity based phase detector system with post-accelerator stripper after the analyzing magnet, and a high efficiency multi harmonic buncher. Installation of a turbo pump based stripper gas recirculation system in the terminal is also planned. A brief description of utilization of the machine will be given.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kwan, J.W.; Arbelaez, D.; Bieniosek, F.M.

The Heavy Ion Fusion Science Virtual National Laboratory in the USA is constructing a new Neutralized Drift Compression eXperiment (NDCX-II) at LBNL. This facility is being developed for high energy density physics and inertial fusion energy research. The 12 m long induction linac in NDCX-II will produce a Li{sup +} beam pulse, at energies of 1.2-3 MeV, to heat target material to the warm dense matter regime ({approx} 1 eV). By making use of special acceleration voltage waveforms, 2.5T solenoid focusing, and neutralized drift compression, 20 - 50 nC of beam charge from the ion source will be compressed longitudinallymore » and radially to achieve a subnanosecond pulse length and mm-scale target spot size. The original Neutralized Drift Compression Experiment (NDCX-I) has successfully demonstrated simultaneous radial and longitudinal compression by imparting a velocity ramp to the ion beam, which then drifts in a neutralizing plasma to and through the final focussing solenoid and onto the target. At higher kinetic energy and current, NDCX-II will offer more than 100 times the peak energy fluence on target of NDCX-I. NDCX-II makes use of many parts from the decommissioned Advanced Test Accelerator (ATA) at LLNL. It includes 27 lattice periods between the injector and the neutralized drift compression section (Figure 1). There are 12 energized induction cells, 9 inactive cells which provide drift space, and 6 diagnostic cells which provide beam diagnostics and pumping. Custom pulsed power systems generate ramped waveforms for the first 7 induction cells, so as to quickly compress the beam from 600 ns at the injector down to 70 ns. After this compression, the high voltages of the ATA Blumleins are then used to rapidly add energy to the beam. The Blumleins were designed to match the ferrite core volt-seconds with pulses up to 250 kV and a fixed FWHM of 70 ns. The machine is limited to a pulse repetition rate of once every 20 seconds due to cooling requirements. The NDCX-II beam is highly space-charge dominated. The 1-D ASP code was used to synthesize high voltage waveform for acceleration, while the 3-D Warp particle-in-cell code was used for detailed design of the lattice. The Li{sup +} ion was chosen because its Bragg Peak energy (at {approx} 2 MeV) coincides with the NDCX-II beam energy. The 130 keV injector will have a 10.9 cm diameter ion source. Testing of small (0.64 cm diameter) lithium doped alumino-silicate ion sources has demonstrated the current density ({approx} 1 mA/cm{sup 2}) used in the design, with acceptable lifetime. A 7.6 cm diameter source has been successfully produced to verify that the coating method can be applied to such a large emitting area. The ion source will operate at {approx} 1275 C; thus a significant effort was made in the design to manage the 4 kW heating power and the associated cooling requirements. In modifying the ATA induction cells for NDCX-II, the low-field DC solenoids were replaced with 2.5 T pulsed solenoids. The beam pipe diameter was decreased in order to reduce the axial extent of the solenoid fringe fields and to make room for water cooling. In addition, an outer copper cylinder (water-cooled) was used to exclude the solenoid magnetic flux from the ferrite cores. Precise alignment is essential because the beam has a large energy spread due to the rapid pulse compression, such that misalignments lead to corkscrew deformation of the beam and reduced intensity at focus. A novel pulsed-wire measurement method is used to align the pulsed solenoid magnets. Alignment accuracy has been demonstrated to within 100 {micro}m of the induction cell axis. The neutralized drift compression region after the last induction cell is approximately 1.2 m long and includes ferroelectric plasma sources (FEPS) fabricated by PPPL similar to those successfully operating in NDCX-I. The 8-T final focus pulsed solenoid, filtered cathodic arc plasma sources (FCAPS), and target chamber from NDCX-I are to be relocated to NDCX-II. The NDCX-II project started in July 2009 and is expected to complete in fall of 2011. As future funds become available, additional induction cells and pulsed power systems will be added to increase the beam energy.« less

Heat Exchanger Cleaning in Support of Ocean Thermal Energy Conversion (OTEC) - Mechanical Subsystem.

DTIC Science & Technology

1980-12-01

sponge rubber ball, and chlorination systems. In addition, the maintenance procedures utilized at the NCSC test site are provided. jAN 7 1473 EDITION OF...Recirculating Sponge Rubber Balls .. .... ............. 17 Chlorination .. .............. ............. 19 OTEC MAINTENANCE PROCEDURES...C-1 APPENDIX D - RECIRCULATING SPONGE RUBBER BALL. ............... D-1 APPENDIX E - CHLORINATION SYSTEM .. .. ................. E-1 i 1

Periodic bacterial control with peracetic acid in a recirculating aquaculture system and its long-term beneficial effect on fish health

USDA-ARS?s Scientific Manuscript database

Peracetic acid (PAA) is being introduced to aquaculture as a sustainable disinfectant. It is suitable for recirculating aquaculture systems (RAS) because of the low effective concentrations and its minimal impact on biofilter function. The application of PAA in a RAS has a combined impact on fish an...

The impact of water exchange rate on the health and performance of rainbow trout Oncorhynchus mykiss in recirculation aquaculture systems

USDA-ARS?s Scientific Manuscript database

Fish mortality in recirculating aquaculture systems (RAS) has been observed by the authors to increase when RAS are managed at low makeup water exchange rates with relatively high feed loading. The precise etiology of this elevated mortality was unknown, all typical water quality parameters were wit...

The effects of ozonation on select waterborne steroid hormones in recirculation aquaculture systems containing sexually mature Atlantic salmon Salmo salar

USDA-ARS?s Scientific Manuscript database

A controlled 3-month study was conducted in 6 replicated water recirculation aquaculture systems (RAS) containing a mixture of sexually mature and immature Atlantic salmon Salmo salar to determine whether water ozonation is associated with a reduction in waterborne hormones. Post-smolt Atlantic salm...

Investigating the effectiveness of peracetic acid to reduce post-vaccination Saprolegnia spp.-associated mortality in Atlantic salmon parr while assessing impact on nitrification in recirculation aquaculture systems

USDA-ARS?s Scientific Manuscript database

Closed containment operations utilizing recirculation aquaculture systems (RAS) can provide critical barriers to the introduction of obligate fish pathogens (Timmons and Ebeling, 2010); however, opportunistic pathogens will be present and can cause disease when conditions favor these agents. One par...

29 CFR 1910.124 - General requirements for dipping and coating operations.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) Chemical reaction. (c) What requirements must I follow to recirculate exhaust air into the workplace? (1) You may not recirculate exhaust air when any substance in that air poses a health hazard to employees... Liquids. (5) When you use mechanical ventilation, it must draw the flow of air into a hood or exhaust duct...

Evaluating the chronic effects of nitrate on the health and performance of post-smolt Atlantic salmon Salmo salar in freshwater recirculation aquaculture systems

USDA-ARS?s Scientific Manuscript database

Commercial production of Atlantic salmon smolts, post-smolts, and market-size fish using land-based recirculation aquaculture systems (RAS) is expanding. RAS generally provide a nutrient-rich environment in which nitrate accumulates as an end-product of nitrification. An 8-month study was conducted ...

Membrane biological reactors to remove nitrate, digest biosolids, and eliminate water flushing requirements within replicated recirculation systems culturing rainbow trout

USDA-ARS?s Scientific Manuscript database

Nutrients, particularly nitrate (NO3), can accumulate to very high levels within low exchange recirculation aquaculture systems (RAS) and negatively impact a number of cultured species. To prevent the harmful effects of nitrate accumulation and to dispose of concentrated waste biosolids, many RAS ar...

40 CFR 258.42 - Approval of site-specific flexibility requests in Indian country.

Code of Federal Regulations, 2012 CFR

2012-07-01

... VI. (2) The owner and/or operator may operate Phase VI as a bioreactor by recirculating leachate and... IVA by recirculating leachate and landfill gas condensate, and by adding storm water and groundwater... than a 30-cm depth of leachate on the liner. (5) The owner and/or operator shall submit reports to the...

40 CFR 258.42 - Approval of site-specific flexibility requests in Indian country.

Code of Federal Regulations, 2013 CFR

2013-07-01

... VI. (2) The owner and/or operator may operate Phase VI as a bioreactor by recirculating leachate and... IVA by recirculating leachate and landfill gas condensate, and by adding storm water and groundwater... than a 30-cm depth of leachate on the liner. (5) The owner and/or operator shall submit reports to the...

40 CFR 258.42 - Approval of site-specific flexibility requests in Indian country.

Code of Federal Regulations, 2014 CFR

2014-07-01

... VI. (2) The owner and/or operator may operate Phase VI as a bioreactor by recirculating leachate and... IVA by recirculating leachate and landfill gas condensate, and by adding storm water and groundwater... than a 30-cm depth of leachate on the liner. (5) The owner and/or operator shall submit reports to the...

Evaluating standard operating procedures to mitigate off-flavor from Atlantic salmon Salmo salar cultured in a semi-commercial scale recirculating aquaculture system

USDA-ARS?s Scientific Manuscript database

Fish cultured within water recirculating aquaculture systems (RAS) can acquire “earthy” or “musty” off-flavors due to bioaccumulation of the compounds geosmin and 2-methylisoborneol (MIB), respectively, which are produced by certain bacterial species present in RAS biosolids and microbial biofilms. ...

77 FR 20059 - License Amendment To Increase the Maximum Reactor Power Level, Florida Power & Light Company...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-03

... surface evaporation. The canals are a closed recirculating loop that serves as the ultimate heat sink for...) for water discharges to an onsite closed-loop recirculation cooling canal system. The seasonal... to 90 [deg]F (21 [deg]C to 32 [deg]C). Additionally, the CCS water is hyper-saline (twice the...

Achromatic recirculated chicane with fixed geometry and independently variable path length and momentum compaction

DOEpatents

Douglas, David R.; Neil, George R.

2005-04-26

A particle beam recirculated chicane geometry that, through the inducement of a pair of 180 degree bends directed by the poles of a pair of controllable magnetic fields allows for variation of dipole position, return loop radii and steering/focussing, thereby allowing the implementation of independent variation of path length and momentum compaction.

Production of market-size North American strain Atlantic salmon Salmo salar in a land-based recirculation aquaculture system using freshwater

USDA-ARS?s Scientific Manuscript database

There is interest in culturing Atlantic salmon Salmo salar to market-size in land-based, closed containment systems that use recirculation aquaculture systems (RAS), as this technology often enables facilities to locate near major markets, obtain permits, exclude obligate pathogens, and/or reduce en...

Low chemical concentrating steam generating cycle

DOEpatents

Mangus, James D.

1983-01-01

A steam cycle for a nuclear power plant having two optional modes of operation. A once-through mode of operation uses direct feed of coolant water to an evaporator avoiding excessive chemical concentration buildup. A recirculation mode of operation uses a recirculation loop to direct a portion of flow from the evaporator back through the evaporator to effectively increase evaporator flow.

Fillet quality and processing attributes of postsmolt Atlantic salmon, Salmo salar, fed a fishmeal-free diet and a fishmeal-based diet in recirculation aquaculture systems

USDA-ARS?s Scientific Manuscript database

Many studies have evaluated the adequacy of alternate ingredient diets for Atlantic salmon, Salmo salar, mainly with focus on fish performance and health; however, comprehensive analysis of fillet quality is lacking, particularly for salmon fed these diets in recirculation aquaculture systems (RAS)....

Circulation of the gyres of the world ocean: Observation modeling using TOPEX/Poseidon altimeter data

NASA Technical Reports Server (NTRS)

Fu, Lee-Lueng; Zlotnicki, V.; Holland, W. R.; Malanotte-Rizzoli, P.

1991-01-01

The overall objectives of the proposed investigation are to study the dynamics of the large-scale recirculating cells of water in the ocean, which are loosely defined as 'gyres' in this study. A gyre is normally composed of a swift western boundary current (e.g., the Gulf Stream and the Kuroshio), a tight recirculating cell attached to the current, and a large-scale sluggish return flow. The water, of course, is not entirely recirculating within a gyre. The exchange of water among gyres is an important process in maintaining the meridional heat transport of the ocean. The gyres constitute a major mode of water movement in the ocean and play significant roles in the global climate system.

A replacement LH2 recirculation line before installation in Discovery

NASA Technical Reports Server (NTRS)

1999-01-01

A spare four-inch diameter LH2 recirculation line (shown in photo) will be used to replace a damaged LH2 line in the orbiter Discovery. The line recirculates hydrogen from the Shuttle main engines back to the external tank during prelaunch engine conditioning. Workers noted a dent in the line during routine aft compartment inspections Tuesday, Dec. 7. The dent measures 12 inches long and about =-inch deep. Managers expect the replacement work to take about 3 days, followed by system retests and final aft compartment close-outs. Preliminary assessments reflect a launch date of Space Shuttle Discovery on mission STS-103 no earlier than Dec. 16. STS-103 is the third servicing mission for the Hubble Space Telescope.

A portable gas recirculation unit for gaseous detectors

NASA Astrophysics Data System (ADS)

Guida, R.; Mandelli, B.

2017-10-01

The use of greenhouse gases (usually C2H2F4, CF4 and SF6) is sometimes necessary to achieve the required performance for some gaseous detectors. The consumption of these gases in the LHC systems is reduced by recycling the gas mixture thanks to a complex gas recirculation system. Beyond greenhouse gas consumption due to LHC systems, a considerable contribution is generated by setups used for LHC detector upgrade projects, R&D activities, detector quality assurance or longevity tests. In order to minimise this emission, a new flexible and portable gas recirculation unit has been developed. Thanks to its low price, flexibility and user-friendly operation it can be easily adapted for the different types of detector systems and set-ups.

Removal of sodium chloride from human urine via batch recirculation electrodialysis at constant applied voltage

NASA Technical Reports Server (NTRS)

Gordils-Striker, Nilda E.; Colon, Guillermo

2003-01-01

The removal of sodium chloride (NaCl) from human urine using a six-compartment electrodialysis cell with batch recirculation mode of operation for use in advanced life support systems (ALSS) was studied. From the results obtained, batch recirculation at constant applied voltage yields high values (approximately 94% of NaCl removal. Based on the results, the initial rate of NaCl removal was correlated to a power function of the applied voltage: -r=2.0 x 10(-4)E(3.8). With impedance spectroscopy methods, it was also found that the anion membranes were more affected by fouling with an increase of the ohmic resistance of almost 11% compared with 7.4% for the cationic ones.

Characterization of Mycobacterium salmoniphilum as causal agent of mycobacteriosis in Atlantic salmon, Salmo salar L., from a freshwater recirculation system.

PubMed

Aro, L; Correa, K; Martínez, A; Ildefonso, R; Yáñez, J M

2014-04-01

Thirty Atlantic salmon, Salmo salar L., with low corporal condition relative to other fish present in the culture system, were sampled from a freshwater recirculation pisciculture located in Chile. The most characteristic signs and lesions were cachexia and presence of multiple greyish-white granulomas within internal organs. The external and internal lesions, along with the microscopic, histologic and biochemical findings, were consistent with mycobacteriosis. The identification of Mycobacterium salmoniphilum as the causal agent of the lesions was possible through the use of molecular analyses. This study represents the first report of Mycobacterium salmoniphilum in a freshwater recirculation system and the first case of fish mycobacteriosis described in Chile. © 2013 John Wiley & Sons Ltd.

Development and testing of a pulsed helium ion source for probing materials and warm dense matter studies

NASA Astrophysics Data System (ADS)

Ji, Q.; Seidl, P. A.; Waldron, W. L.; Takakuwa, J. H.; Friedman, A.; Grote, D. P.; Persaud, A.; Barnard, J. J.; Schenkel, T.

2016-02-01

The neutralized drift compression experiment was designed and commissioned as a pulsed, linear induction accelerator to drive thin targets to warm dense matter (WDM) states with peak temperatures of ˜1 eV using intense, short pulses (˜1 ns) of 1.2 MeV lithium ions. At that kinetic energy, heating a thin target foil near the Bragg peak energy using He+ ions leads to more uniform energy deposition of the target material than Li+ ions. Experiments show that a higher current density of helium ions can be delivered from a plasma source compared to Li+ ions from a hot plate type ion source. He+ beam pulses as high as 200 mA at the peak and 4 μs long were measured from a multi-aperture 7-cm-diameter emission area. Within ±5% variation, the uniform beam area is approximately 6 cm across. The accelerated and compressed pulsed ion beams can be used for materials studies and isochoric heating of target materials for high energy density physics experiments and WDM studies.

Development and testing of a pulsed helium ion source for probing materials and warm dense matter studies.

PubMed

Ji, Q; Seidl, P A; Waldron, W L; Takakuwa, J H; Friedman, A; Grote, D P; Persaud, A; Barnard, J J; Schenkel, T

2016-02-01

The neutralized drift compression experiment was designed and commissioned as a pulsed, linear induction accelerator to drive thin targets to warm dense matter (WDM) states with peak temperatures of ∼1 eV using intense, short pulses (∼1 ns) of 1.2 MeV lithium ions. At that kinetic energy, heating a thin target foil near the Bragg peak energy using He(+) ions leads to more uniform energy deposition of the target material than Li(+) ions. Experiments show that a higher current density of helium ions can be delivered from a plasma source compared to Li(+) ions from a hot plate type ion source. He(+) beam pulses as high as 200 mA at the peak and 4 μs long were measured from a multi-aperture 7-cm-diameter emission area. Within ±5% variation, the uniform beam area is approximately 6 cm across. The accelerated and compressed pulsed ion beams can be used for materials studies and isochoric heating of target materials for high energy density physics experiments and WDM studies.

Development and testing of a pulsed helium ion source for probing materials and warm dense matter studies

DOE PAGES

Ji, Q.; Seidl, P. A.; Waldron, W. L.; ...

2015-11-12

In this paper, the neutralized drift compression experiment was designed and commissioned as a pulsed, linear induction accelerator to drive thin targets to warm dense matter (WDM) states with peak temperatures of ~1 eV using intense, short pulses (~1 ns) of 1.2 MeV lithium ions. At that kinetic energy, heating a thin target foil near the Bragg peak energy using He + ions leads to more uniform energy deposition of the target material than Li + ions. Experiments show that a higher current density of helium ions can be delivered from a plasma source compared to Li + ions frommore » a hot plate type ion source. He + beam pulses as high as 200 mA at the peak and 4 μs long were measured from a multi-aperture 7-cm-diameter emission area. Within ±5% variation, the uniform beam area is approximately 6 cm across. Finally, the accelerated and compressed pulsed ion beams can be used for materials studies and isochoric heating of target materials for high energy density physics experiments and WDM studies.« less

Ion velocities in the presheath of electronegative, radio-frequency plasmas measured by low-energy cutoff

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sobolewski, Mark A.; Wang, Yicheng; Goyette, Amanda

2016-07-11

Simple kinematic considerations indicate that, under certain conditions in radio-frequency (rf) plasmas, the amplitude of the low-energy peak in ion energy distributions (IEDs) measured at an electrode depends sensitively on ion velocities upstream, at the presheath/sheath boundary. By measuring this amplitude, the velocities at which ions exit the presheath can be determined and long-standing controversies regarding presheath transport can be resolved. Here, IEDs measured in rf-biased, inductively coupled plasmas in CF{sub 4} gas determined the presheath exit velocities of all significant positive ions: CF{sub 3}{sup +}, CF{sub 2}{sup +}, CF{sup +}, and F{sup +}. At higher bias voltages, we detectedmore » essentially the same velocity for all four ions. For all ions, measured velocities were significantly lower than the Bohm velocity and the electropositive ion sound speed. Neither is an accurate boundary condition for rf sheaths in electronegative gases: under certain low-frequency, high-voltage criteria defined here, either yields large errors in predicted IEDs. These results indicate that many widely used sheath models will need to be revised.« less

Ion-Acoustic Wave-Particle Energy Flow Rates

NASA Astrophysics Data System (ADS)

Berumen, Jorge; Chu, Feng; Hood, Ryan; Mattingly, Sean; Skiff, Fred

2017-10-01

We present an experimental characterization of the energy flow rates for ion acoustic waves. The experiment is performed in a cylindrical, magnetized, singly-ionized Argon, inductively-coupled gas discharge plasma that is weakly collisional with typical conditions: n 109cm-3 Te 9 eV and B 660 kG. A 4 ring antenna with diameter similar to the plasma diameter is used for launching the waves. A survey of the zeroth and first order ion velocity distribution functions (IVDF) is done using Laser-Induced Fluorescence (LIF) as the main diagnostics method. Using these IVDFs along with Vlasov's equation the different energy rates are measured for different values of ion velocity and separation from the antenna. We would like to acknowledge DOE DE-FG02-99ER54543 for their financial support throughout this research.

Plasma-filled applied B ion diode experiments using a plasma opening switch

DOE Office of Scientific and Technical Information (OSTI.GOV)

Renk, T.J.

1994-12-15

In order for a plasma opening switch (POS) to open quickly and transfer power efficiently from an inductively charged vacuum transmission line to an applied B ion diode, the load impedance of the ion diode may be required to have an initial low impedance phase. A plasma-filled diode has such an impedance history. To test the effect of a plasma-filled diode on POS-diode coupling, a drifting plasma was introduced from the cathode side of an applied B ion diode operated on the LION accelerator (1.5 MV, 4 [Omega], 40 ns) at Cornell University. This plasma readily crossed the 2.1 Tmore » magnetic insulation field of the diode, and resulted in both increased diode electrical power, and an increased ability of the ion beam to remove material from a target. The plasma did not appear to have a noticeable effect on local beam steering angle.« less

Heavy ion induced mutations in mammalian cells: Cross sections and molecular analysis

NASA Technical Reports Server (NTRS)

Stoll, U.; Schmidt, P.; Schneider, E.; Kiefer, J.

1994-01-01

Our investigations of heavy ion-induced mutations in mammalian cells, which had been begun a few years ago, were systematically continued. For the first time, it was possible to cover a large LET range with a few kinds of ions. To do this, both UNILAC and SIS were used to yield comparable data for a large energy range. This is a necessary condition for a comprehensive description of the influence of such ion parameters as energy and LET. In these experiments, the induced resistance against the poison 6-thioguanin (6-TG), which is linked to the HPRT locus on the genome, is being used as mutation system. In addition to the mutation-induction cross-section measurements, the molecular changes of the DNA are being investigated by means of Multiplex PCR ('Polymerase Chain Reaction') gene amplification. From these experiments we expect further elucidation of the mutation-inducing mechanisms composing the biological action of heavy-ion radiation.

Partial breaking of the Coulombic ordering of ionic liquids confined in carbon nanopores

PubMed Central

Futamura, Ryusuke; Iiyama, Taku; Takasaki, Yuma; Gogotsi, Yury; Biggs, Mark J.; Salanne, Mathieu; Ségalini, Julie; Simon, Patrice; Kaneko, Katsumi

2017-01-01

Ionic liquids are composed of equal quantities of positive and negative ions. In the bulk, electrical neutrality occurs in these liquids due to Coulombic ordering, in which ion shells of alternating charge form around a central ion. Their structure under confinement is far less well understood. This hinders the widespread application of ionic liquids in technological applications. Here we use scattering experiments to resolve the structure of the widely used ionic liquid (EMI-TFSI) when it is confined inside nanoporous carbons. We show that Coulombic ordering reduces when the pores can only accommodate a single layer of ions. Instead, equally-charged ion pairs are formed due to the induction of an electric potential of opposite sign in the carbon pore walls. This non-Coulombic ordering is further enhanced in the presence of an applied external electric potential. This finding opens the door for the design of better materials for electrochemical applications. PMID:28920938

Low-energy plasma immersion ion implantation to induce DNA transfer into bacterial E. coli

NASA Astrophysics Data System (ADS)

Sangwijit, K.; Yu, L. D.; Sarapirom, S.; Pitakrattananukool, S.; Anuntalabhochai, S.

2015-12-01

Plasma immersion ion implantation (PIII) at low energy was for the first time applied as a novel biotechnology to induce DNA transfer into bacterial cells. Argon or nitrogen PIII at low bias voltages of 2.5, 5 and 10 kV and fluences ranging from 1 × 1012 to 1 × 1017 ions/cm2 treated cells of Escherichia coli (E. coli). Subsequently, DNA transfer was operated by mixing the PIII-treated cells with DNA. Successes in PIII-induced DNA transfer were demonstrated by marker gene expressions. The induction of DNA transfer was ion-energy, fluence and DNA-size dependent. The DNA transferred in the cells was confirmed functioning. Mechanisms of the PIII-induced DNA transfer were investigated and discussed in terms of the E. coli cell envelope anatomy. Compared with conventional ion-beam-induced DNA transfer, PIII-induced DNA transfer was simpler with lower cost but higher efficiency.

Magnesium Ion Acts as a Signal for Capsule Induction in Cryptococcus neoformans

PubMed Central

Rathore, Sudarshan S.; Raman, Thiagarajan; Ramakrishnan, Jayapradha

2016-01-01

Cryptococcal meningitis caused by Cryptococcus neoformans, is a common opportunistic neural infection in immunocompromised individuals. Cryptococcus meningitis is associated with fungal burden with larger capsule size in cerebrospinal fluid (CSF). To understand the role of CSF constituents in capsule enlargement, we have evaluated the effect of artificial CSF on capsule induction in comparison with various other capsule inducing media. Two different strains of C. neoformans, an environmental and a clinical isolates were used in the present study. While comparing the various capsule inducing media for the two different strains of C. neoformans, it was observed that the capsule growth was significantly increased when grown in artificial CSF at pH 5.5, temperature 34°C for ATCC C. neoformans and 37°C for Clinical C. neoformans and with an incubation period of 72 h. In addition, artificial CSF supports biofilm formation in C. neoformans. While investigating the individual components of artificial CSF, we found that Mg2+ ions influence the capsule growth in both environmental and clinical strains of C. neoformans. To confirm our results we studied the expression of four major CAP genes namely, CAP10, CAP59, CAP60, and CAP64 in various capsule inducing media and in different concentrations of Mg2+ and Ca2+. Our results on gene expression suggest that, Mg2+ does have an effect on CAP gene expression, which are important for capsule biosynthesis and virulence. Our findings on the role of Mg2+ ion as a signal for capsule induction will promote a way to elucidate the control mechanisms for capsule biosynthesis in C. neoformans. PMID:27014245

Consequences of atomic layer etching on wafer scale uniformity in inductively coupled plasmas

NASA Astrophysics Data System (ADS)

Huard, Chad M.; Lanham, Steven J.; Kushner, Mark J.

2018-04-01

Atomic layer etching (ALE) typically divides the etching process into two self-limited reactions. One reaction passivates a single layer of material while the second preferentially removes the passivated layer. As such, under ideal conditions the wafer scale uniformity of ALE should be independent of the uniformity of the reactant fluxes onto the wafers, provided all surface reactions are saturated. The passivation and etch steps should individually asymptotically saturate after a characteristic fluence of reactants has been delivered to each site. In this paper, results from a computational investigation are discussed regarding the uniformity of ALE of Si in Cl2 containing inductively coupled plasmas when the reactant fluxes are both non-uniform and non-ideal. In the parameter space investigated for inductively coupled plasmas, the local etch rate for continuous processing was proportional to the ion flux. When operated with saturated conditions (that is, both ALE steps are allowed to self-terminate), the ALE process is less sensitive to non-uniformities in the incoming ion flux than continuous etching. Operating ALE in a sub-saturation regime resulted in less uniform etching. It was also found that ALE processing with saturated steps requires a larger total ion fluence than continuous etching to achieve the same etch depth. This condition may result in increased resist erosion and/or damage to stopping layers using ALE. While these results demonstrate that ALE provides increased etch depth uniformity, they do not show an improved critical dimension uniformity in all cases. These possible limitations to ALE processing, as well as increased processing time, will be part of the process optimization that includes the benefits of atomic resolution and improved uniformity.

Radiation-Induced Cytogenetic Damage as a Predictor of Cancer Risk for Protons and Fe Ions

NASA Technical Reports Server (NTRS)

Williams, Jerry R.

1999-01-01

We have successfully completed the series of experiments planned for year 1 and the first part of year 2 measuring the induction of chromosome aberrations induced in multiple cell types by three model space radiations: Fe-ions, protons and photons. Most of these data have now been compiled and a significant part subjected to detailed data analyses, although continuing data analysis is an important part of our current and future efforts. These analyses are directed toward defining the patterns of chromosomal damage induction by the three radiations and the extent to which such patterns are dependent on the type of cell irradiated. Our studies show significant differences, both quantitatively and qualitatively, between response of different cell types to these radiations however there is an overall pattern that characterizes each type of radiation in most cell lines. Thus our data identifies general dose-response patterns for each radiation for induction of multiple types of chromosomal aberrations but also identifies significant differences in response between some cell types. Specifically, we observe significant resistance for induction of aberrations in rat mammary epithelial cells when they are irradiated in vivo and assayed in vitro. Further, we have observed some remarkable differences in susceptibility to certain radiation-induced aberrations in cells whose genome has been modulated for two cancer- relevant genes, TP53 and CDKNIA. This data, if confirmed, may represent the first evidence of gene-specific differences in cellular metabolism of damage induced by densely-ionizing radiation that confers substantial sensitivity to protons compared to photons.

Evaluating leachate recirculation with cellulase addition to enhance waste biostabilisation and landfill gas production.

PubMed

Frank, R R; Davies, S; Wagland, S T; Villa, R; Trois, C; Coulon, F

2016-09-01

The effect of leachate recirculation with cellulase augmentation on municipal solid waste (MSW) biostabilisation and landfill gas production was investigated using batch bioreactors to determine the optimal conditions of moisture content, temperature and nutrients. Experimentation was thereafter scaled-up in 7L bioreactors. Three conditions were tested including (1) leachate recirculation only, (2) leachate recirculation with enzyme augmentation and (3) no leachate recirculation (control). Cumulative biogas production of the batch tests indicated that there was little difference between the leachate and control test conditions, producing on average 0.043m(3)biogaskg(-1) waste. However the addition of cellulase at 15×10(6)Utonne(-1) waste doubled the biogas production (0.074m(3)biogaskg(-1) waste). Similar trend was observed with the bioreactors. Cellulase addition also resulted in the highest COD reduction in both the waste and the leachate samples (47% and 42% COD reduction, respectively). In both cases, the quantity of biogas produced was closer to the lower value of theoretical and data-based biogas prediction indicators (0.05-0.4m(3)biogaskg(-1) waste). This was likely due to a high concentration of heavy metals present in the leachate, in particular Cr and Mn, which are known to be toxic to methanogens. The cost-benefit analysis (CBA) based on the settings of the study (cellulase concentration of 15×10(6)Utonne(-1) waste) showed that leachate bioaugmentation using cellulase is economically viable, with a net benefit of approximately €12.1million on a 5Mt mixed waste landfill. Copyright © 2016 Elsevier Ltd. All rights reserved.

Conditions for coherent-synchrotron-radiation-induced microbunching suppression in multibend beam transport or recirculation arcs

NASA Astrophysics Data System (ADS)

Tsai, C.-Y.; Di Mitri, S.; Douglas, D.; Li, R.; Tennant, C.

2017-02-01

The coherent synchrotron radiation (CSR) of a high-brightness electron beam traversing a series of dipoles, such as transport or recirculation arcs, may result in beam phase space degradation. On one hand, CSR can perturb electron transverse motion in dispersive regions along the beam line and possibly cause emittance growth. On the other hand, the CSR effect on the longitudinal beam dynamics could result in microbunching instability. For transport arcs, several schemes have been proposed to suppress the CSR-induced emittance growth. Correspondingly, a few scenarios have been introduced to suppress CSR-induced microbunching instability, which however mostly aim for linac-based machines. In this paper we provide sufficient conditions for suppression of CSR-induced microbunching instability along transport or recirculation arcs. Examples are presented with the relevant microbunching analyses carried out by our developed semianalytical Vlasov solver [C.-Y. Tsai, D. Douglas, R. Li, and C. Tennant, Linear microbunching analysis for recirculation machines, Phys. Rev. ST Accel. Beams 19, 114401 (2016), 10.1103/PhysRevAccelBeams.19.114401]. The example lattices include low-energy (˜100 MeV ) and high-energy (˜1 GeV ) recirculation arcs, and medium-energy compressor arcs. Our studies show that lattices satisfying the proposed conditions indeed have microbunching gain suppressed. Beam current dependences of maximal CSR microbunching gains are also demonstrated, which should help outline a beam line design for different scales of nominal currents. We expect this analysis can shed light on the lattice design approach that aims to control the CSR-induced microbunching.

Turbulence measurements of high shear flow fields in a turbomachine seal configuration

NASA Technical Reports Server (NTRS)

Morrison, Gerald L.; Deotte, Robert E., Jr.; Thames, H. Davis, III.

1992-01-01

The mean velocity and Reynolds stress tensor throughout a whirling annular seal are presented. The data was collected with a three dimensional laser Doppler velocimeter using phase averaging. Two axial flow conditions (Re = 12,000 and 24,000) were studied at one shaft speed (Ta = 6,600). The eccentricity and whirl ratios were 50 and 100 percent, respectively. There is a region of high axial momentum in this region is higher in the low Reynolds number case due to an axial recirculation zone that occurs on the suction side of the rotor at the inlet. The recirculation zone does not occur in the high Reynolds number case. At both Reynolds numbers, there is a recirculation zone on the rotor surface in the pressure side of the inlet. This recirculation zone extends from 20 to 200 degrees rotor zenith in the tangential direction, and is one third of a clearance wide radially. The high Reynolds number recirculation zone is 1.5 mean clearances long, while the low Reynolds number zone extends 2 mean clearances downstream. When compared to previous studies, it is apparent that the tangential momentum is no greater for a seal with whirl than for one without if other parameters are constant. Areas of high tangential momentum occur in the clearance where the axial momentum is low. Average exit plane tangential velocities in the high Reynolds number case are 1.5 times greater than those in the other flow case. These results are in general agreement with predictions made by other investigators.

Semi-continuous anaerobic co-digestion of cow manure and steam-exploded Salix with recirculation of liquid digestate.

PubMed

Estevez, Maria M; Sapci, Zehra; Linjordet, Roar; Schnürer, Anna; Morken, John

2014-04-01

The effects of recirculating the liquid fraction of the digestate during mesophilic anaerobic co-digestion of steam-exploded Salix and cow manure were investigated in laboratory-scale continuously stirred tank reactors. An average organic loading rate of 2.6 g VS L(-1) d(-1) and a hydraulic retention time (HRT) of 30 days were employed. Co-digestion of Salix and manure gave better methane yields than digestion of manure alone. Also, a 16% increase in the methane yield was achieved when digestate was recirculated and used instead of water to dilute the feedstock (1:1 dilution ratio). The reactor in which the larger fraction of digestate was recirculated (1:3 dilution ratio) gave the highest methane yields. Ammonia and volatile fatty acids did not reach inhibitory levels, and some potentially inhibitory compounds released during steam explosion (i.e., furfural and 5-hydroxy methyl furfural) were only detected at trace levels throughout the entire study period. However, accumulation of solids, which was more pronounced in the recycling reactors, led to decreased methane yields in those systems after three HRTs. Refraining from the use of fresh water to dilute biomass with a high-solids content and obtaining a final digestate with increased dry matter content might offer important economic benefits in full-scale processes. To ensure long-term stability in such an approach, it would be necessary to optimize separation of the fraction of digestate to be recirculated and also perform proper monitoring to avoid accumulation of solids. Copyright © 2014 Elsevier Ltd. All rights reserved.

A detached eddy simulation model for the study of lateral separation zones along a large canyon-bound river

NASA Astrophysics Data System (ADS)

Alvarez, Laura V.; Schmeeckle, Mark W.; Grams, Paul E.

2017-01-01

Lateral flow separation occurs in rivers where banks exhibit strong curvature. In canyon-bound rivers, lateral recirculation zones are the principal storage of fine-sediment deposits. A parallelized, three-dimensional, turbulence-resolving model was developed to study the flow structures along lateral separation zones located in two pools along the Colorado River in Marble Canyon. The model employs the detached eddy simulation (DES) technique, which resolves turbulence structures larger than the grid spacing in the interior of the flow. The DES-3D model is validated using Acoustic Doppler Current Profiler flow measurements taken during the 2008 controlled flood release from Glen Canyon Dam. A point-to-point validation using a number of skill metrics, often employed in hydrological research, is proposed here for fluvial modeling. The validation results show predictive capabilities of the DES model. The model reproduces the pattern and magnitude of the velocity in the lateral recirculation zone, including the size and position of the primary and secondary eddy cells, and return current. The lateral recirculation zone is open, having continuous import of fluid upstream of the point of reattachment and export by the recirculation return current downstream of the point of separation. Differences in magnitude and direction of near-bed and near-surface velocity vectors are found, resulting in an inward vertical spiral. Interaction between the recirculation return current and the main flow is dynamic, with large temporal changes in flow direction and magnitude. Turbulence structures with a predominately vertical axis of vorticity are observed in the shear layer becoming three-dimensional without preferred orientation downstream.

Determination of glyphosate and phosphate in water by ion chromatography--inductively coupled plasma mass spectrometry detection.

PubMed

Guo, Zhong-Xian; Cai, Qiantao; Yang, Zhaoguang

2005-12-30

Quantitative determination of trace glyphosate and phosphate in waters was achieved by coupling ion chromatography (IC) separation with inductively coupled plasma mass spectrometry (ICP-MS) detection. The separation of glyphosate and phosphate on a polymer anion-exchange column (Dionex IonPac AS16, 4.0 mm x 250 mm) was obtained by eluting them with 20 mM citric acid at 0.50 mL min(-1), and the analytes were detected directly and selectively by ICP-MS at m/z = 31. Parameters affecting their chromatographic behaviors and ICP-MS characteristics were systematically examined. Based on a 500-microL sample injection volume, the detection limits were 0.7 microgL(-1) for both glyphosate and phosphate, and the calibrations were linear up to 400 microgL(-1). Polyphosphates, aminomethylphosphonic acid (the major metabolite of glyphosate), non-polar and other polar phosphorus-containing pesticides showed different chromatographic behaviors from the analytes of interest and therefore did not interference. The determination was also interference free from the matrix anions (nitrate, nitrite, sulphate, chloride, etc.) and metallic ions. The analysis of certified reference material, drinking water, reservoir water and Newater yielded satisfactory results with spiked recoveries of 97.1-107.0% and relative standard deviations of < or = 7.4% (n = 3). Compared to other reported methods for glyphosate and phosphate, the developed IC-ICP-MS method is sensitive and simple, and does not require any chemical derivatization, sample preconcentration and mobile phase conductivity suppression.

Selective electrodiffusion of zinc ions in a Zrt-, Irt-like protein, ZIPB

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lin, W.; Fu, D.; Chai, J.

2010-12-10

All living cells need zinc ions to support cell growth. Zrt-, Irt-like proteins (ZIPs) represent a major route for entry of zinc ions into cells, but how ZIPs promote zinc uptake has been unclear. Here we report the molecular characterization of ZIPB from Bordetella bronchiseptica, the first ZIP homolog to be purified and functionally reconstituted into proteoliposomes. Zinc flux through ZIPB was found to be nonsaturable and electrogenic, yielding membrane potentials as predicted by the Nernst equation. Conversely, membrane potentials drove zinc fluxes with a linear voltage-flux relationship. Direct measurements of metal uptake by inductively coupled plasma mass spectroscopy demonstratedmore » that ZIPB is selective for two group 12 transition metal ions, Zn{sup 2+} and Cd{sup 2+}, whereas rejecting transition metal ions in groups 7 through 11. Our results provide the molecular basis for cellular zinc acquisition by a zinc-selective channel that exploits in vivo zinc concentration gradients to move zinc ions into the cytoplasm.« less

High frequency plasma generator for ion thrusters

NASA Technical Reports Server (NTRS)

Goede, H.; Divergilio, W. F.; Fosnight, V. V.; Komatsu, G.

1984-01-01

The results of a program to experimentally develop two new types of plasma generators for 30 cm electrostatic argon ion thrusters are presented. The two plasma generating methods selected for this study were by radio frequency induction (RFI), operating at an input power frequency of 1 MHz, and by electron cyclotron heating (ECH) at an operating frequency of 5.0 GHz. Both of these generators utilize multiline cusp permanent magnet configurations for plasma confinement and beam profile optimization. The program goals were to develop a plasma generator possessing the characteristics of high electrical efficiency (low eV/ion) and simplicity of operation while maintaining the reliability and durability of the conventional hollow cathode plasma sources. The RFI plasma generator has achieved minimum discharge losses of 120 eV/ion while the ECH generator has obtained 145 eV/ion, assuming a 90% ion optical transparency of the electrostatic acceleration system. Details of experimental tests with a variety of magnet configurations are presented.

Effects of CPII implantation on the characteristics of diamond-like carbon films

NASA Astrophysics Data System (ADS)

Chen, Ya-Chi; Weng, Ko-Wei; Chao, Ching-Hsun; Lien, Shui-Yang; Han, Sheng; Chen, Tien-Lai; Lee, Ying-Chieh; Shih, Han-Chang; Wang, Da-Yung

2009-05-01

A diamond-like carbon film (DLC) was successfully synthesized using a hybrid PVD process, involving a filter arc deposition source (FAD) and a carbon plasma ion implanter (CPII). A quarter-torus plasma duct filter markedly reduced the density of the macro-particles. Graphite targets were used in FAD. Large electron and ion energies generated from the plasma duct facilitate the activation of carbon plasma and the deposition of high-quality DLC films. M2 tool steel was pre-implanted with 45 kV carbon ions before the DLC was deposited to enhance the adhesive and surface properties of the film. The ion mixing effect, the induction of residual stress and the phase transformation at the interface were significantly improved. The hardness of the DLC increased to 47.7 GPa and 56.5 GPa, and the wear life was prolonged to over 70 km with implantation fluences of 1 × 10 17 ions/cm 2 and 2 × 10 17 ions/cm 2, respectively.

Improving Extraction Ion Diode Operation By Introducing An Axial Load

NASA Astrophysics Data System (ADS)

Vesey, R. A.; Desjarlais, M. P.; Greenly, J. B.

1997-11-01

Recent ion diode experiments at Cornell have shown that the presence of an axial current load (in this case an inductive voltage monitor) significantly reduced the electron loss to the anode with some indication of a simultaneous reduction in the beam divergence(J. B. Greenly et al., this conference.). The QUICKSILVER 3D particle-in-cell code has been used to simulate axial loads on the SABRE (6 MV, 250 kA) ion diode at Sandia. Initial results show that an axial load drawing 30% of the total diode current reduces the electron loss by 55% while reducing the ion current by just 15%. With an increased applied magnetic field, the electron loss to the anode face is completely suppressed and ion mode oscillations are strongly damped, albeit with a 40% reduction in the ion current. These results show that further scoping simulations are necessary to understand the mechanism involved and to refine the operating parameters (axial current, B-field, A-K gap) for optimum performance.

Classical confinement and outward convection of impurity ions in the MST RFP

NASA Astrophysics Data System (ADS)

Kumar, S. T. A.; Den Hartog, D. J.; Mirnov, V. V.; Caspary, K. J.; Magee, R. M.; Brower, D. L.; Chapman, B. E.; Craig, D.; Ding, W. X.; Eilerman, S.; Fiksel, G.; Lin, L.; Nornberg, M.; Parke, E.; Reusch, J. A.; Sarff, J. S.

2012-05-01

Impurity ion dynamics measured with simultaneously high spatial and temporal resolution reveal classical ion transport in the reversed-field pinch. The boron, carbon, oxygen, and aluminum impurity ion density profiles are obtained in the Madison Symmetric Torus [R. N. Dexter et al., Fusion Technol. 19, 131 (1991)] using a fast, active charge-exchange-recombination-spectroscopy diagnostic. Measurements are made during improved-confinement plasmas obtained using inductive control of tearing instability to mitigate stochastic transport. At the onset of the transition to improved confinement, the impurity ion density profile becomes hollow, with a slow decay in the core region concurrent with an increase in the outer region, implying an outward convection of impurities. Impurity transport from Coulomb collisions in the reversed-field pinch is classical for all collisionality regimes, and analysis shows that the observed hollow profile and outward convection can be explained by the classical temperature screening mechanism. The profile agrees well with classical expectations. Experiments performed with impurity pellet injection provide further evidence for classical impurity ion confinement.

Design and performance of recirculating systems for Atlantic salmon (Salmo salar) at the USDA ARS National Cold Water Marine Aquaculture Center (Franklin, Maine)

USDA-ARS?s Scientific Manuscript database

Atlantic salmon cultured in the NCWMAC breeding program have grown well in the fish culture systems during the first 3 years of operation. The systems were operated at approximately 98% reuse (2% makeup water on the basis of flow rate). The water recirculating systems maintained acceptable water qua...

Engine bleed air reduction in DC-10

NASA Technical Reports Server (NTRS)

Newman, W. H.; Viele, M. R.

1980-01-01

An 0.8 percent fuel savings was achieved by a reduction in engine bleed air through the use of cabin air recirculation. The recirculation system was evaluated in revenue service on a DC-10. The cabin remained comfortable with reductions in cabin fresh air (engine bleed air) as much as 50 percent. Flight test verified the predicted fuel saving of 0.8 percent.

Removal of Nutrients from Septic Effluent with Re-circulated Hybrid Tidal Flow Constructed Wetland

Treesearch

Lihua Cui; Jigkun Feng; Ying Ouyang; Peiwen Deng

2012-01-01

Hybrid tidal flow constructed wetland (CW) with recirculation is an improved biological and engineering technique for removal of excess nutrients and certain pollutants from wastewater. This study investigated the removal efficiency of total phosphorus (TP), ammonia-nitrogen (NH3-N), and total nitrogen (TN) from septic tank effluent with the hybrid tidal flow CW system...

Use of low temperature blowers for recirculation of hot gases

DOEpatents

Maru, H.C.; Forooque, M.

1982-08-19

An apparatus is described for maintaining motors at low operating temperatures during recirculation of hot gases in fuel cell operations and chemical processes such as fluidized bed coal gasification. The apparatus includes a means for separating the hot process gas from the motor using a secondary lower temperature gas, thereby minimizing the temperature increase of the motor and associated accessories.

Evaluation of depuration procedures to mitigate the off-flavor compounds geosmin and 2-methylisoborneol from Atlantic salmon Salmo salar raised to market-size in recirculating aquaculture systems

USDA-ARS?s Scientific Manuscript database

Fish cultured within water recirculating aquaculture systems (RAS) can acquire “earthy” or “musty” off-flavors due to bioaccumulation of the compounds geosmin and 2-methylisoborneol (MIB), respectively, which are produced by certain bacterial species present in RAS biosolids and microbial biofilms. ...

Effects of pH on biomass, geosmin, and 2-methylisoborneol production and cellular activity by Streptomyces luridiscabiei isolated from a rainbow trout recirculating aquaculture system

USDA-ARS?s Scientific Manuscript database

Rainbow trout (Oncorhynchus mykiss) grown in recirculating aquaculture systems (RAS) can acquire “earthy” and “musty” taints due to bioaccumulation of geosmin and 2-methyisoborneol (MIB), respectively, in the fish flesh. Certain species of actinomycetes which produce these compounds are attributed a...

The effects of long-term 20 mg/L carbon dioxide exposure on the health and performance of Atlantic salmon Salmo salar post-smolts in water recirculation aquaculture systems

USDA-ARS?s Scientific Manuscript database

Previous research and experience has linked elevated dissolved carbon dioxide (CO2) to reduced growth performance, poor feed conversion, and a variety of health issues in farm-raised fish, including Atlantic salmon Salmo salar. Supplemental control measures in water recirculation aquaculture systems...