Sample records for recognize individuals based

  1. Prosopography, prosoporecognography and the Prosoporecognographical Chart.

    PubMed

    Santos-Filho, E F; Pereira, H B B

    2017-11-01

    Recognizing and identifying an individual based on his or her face is a technical and scientific challenge and the objective of our investigation. This article's goal is to establish a method, a foundation and an instrument for carrying out the process of recognizing and identifying an individual. Both the construction of the term and the deepening, conceptualization and epistemology of the process of describing and representing the face through a particular method of recognizing and identifying individuals are described in this article. The proposal of the Prosoporecognographical Chart is an important step in the facial-identification process, establishing taxonomic parameters for the phenotypic manifestations of the elements constituting the face. Based on the proposal presented here, the construction of a protocol for the process of recognizing and identifying an individual can be implemented computationally. Copyright © 2017. Published by Elsevier Ltd.

  2. Smartphone-Based Escalator Recognition for the Visually Impaired

    PubMed Central

    Nakamura, Daiki; Takizawa, Hotaka; Aoyagi, Mayumi; Ezaki, Nobuo; Mizuno, Shinji

    2017-01-01

    It is difficult for visually impaired individuals to recognize escalators in everyday environments. If the individuals ride on escalators in the wrong direction, they will stumble on the steps. This paper proposes a novel method to assist visually impaired individuals in finding available escalators by the use of smartphone cameras. Escalators are recognized by analyzing optical flows in video frames captured by the cameras, and auditory feedback is provided to the individuals. The proposed method was implemented on an Android smartphone and applied to actual escalator scenes. The experimental results demonstrate that the proposed method is promising for helping visually impaired individuals use escalators. PMID:28481270

  3. Vocal Identity Recognition in Autism Spectrum Disorder

    PubMed Central

    Lin, I-Fan; Yamada, Takashi; Komine, Yoko; Kato, Nobumasa; Kato, Masaharu; Kashino, Makio

    2015-01-01

    Voices can convey information about a speaker. When forming an abstract representation of a speaker, it is important to extract relevant features from acoustic signals that are invariant to the modulation of these signals. This study investigated the way in which individuals with autism spectrum disorder (ASD) recognize and memorize vocal identity. The ASD group and control group performed similarly in a task when asked to choose the name of the newly-learned speaker based on his or her voice, and the ASD group outperformed the control group in a subsequent familiarity test when asked to discriminate the previously trained voices and untrained voices. These findings suggest that individuals with ASD recognized and memorized voices as well as the neurotypical individuals did, but they categorized voices in a different way: individuals with ASD categorized voices quantitatively based on the exact acoustic features, while neurotypical individuals categorized voices qualitatively based on the acoustic patterns correlated to the speakers' physical and mental properties. PMID:26070199

  4. Vocal Identity Recognition in Autism Spectrum Disorder.

    PubMed

    Lin, I-Fan; Yamada, Takashi; Komine, Yoko; Kato, Nobumasa; Kato, Masaharu; Kashino, Makio

    2015-01-01

    Voices can convey information about a speaker. When forming an abstract representation of a speaker, it is important to extract relevant features from acoustic signals that are invariant to the modulation of these signals. This study investigated the way in which individuals with autism spectrum disorder (ASD) recognize and memorize vocal identity. The ASD group and control group performed similarly in a task when asked to choose the name of the newly-learned speaker based on his or her voice, and the ASD group outperformed the control group in a subsequent familiarity test when asked to discriminate the previously trained voices and untrained voices. These findings suggest that individuals with ASD recognized and memorized voices as well as the neurotypical individuals did, but they categorized voices in a different way: individuals with ASD categorized voices quantitatively based on the exact acoustic features, while neurotypical individuals categorized voices qualitatively based on the acoustic patterns correlated to the speakers' physical and mental properties.

  5. Recognizing Bedside Events Using Thermal and Ultrasonic Readings

    PubMed Central

    Asbjørn, Danielsen; Jim, Torresen

    2017-01-01

    Falls in homes of the elderly, in residential care facilities and in hospitals commonly occur in close proximity to the bed. Most approaches for recognizing falls use cameras, which challenge privacy, or sensor devices attached to the bed or the body to recognize bedside events and bedside falls. We use data collected from a ceiling mounted 80 × 60 thermal array combined with an ultrasonic sensor device. This approach makes it possible to monitor activity while preserving privacy in a non-intrusive manner. We evaluate three different approaches towards recognizing location and posture of an individual. Bedside events are recognized using a 10-second floating image rule/filter-based approach, recognizing bedside falls with 98.62% accuracy. Bed-entry and exit events are recognized with 98.66% and 96.73% accuracy, respectively. PMID:28598394

  6. Model for multi-stand management based on structural attributes of individual stands

    Treesearch

    G.W. Miller; J. Sullivan

    1997-01-01

    A growing interest in managing forest ecosystems calls for decision models that take into account attribute goals for large forest areas while continuing to recognize the individual stand as a basic unit of forest management. A dynamic, nonlinear forest management model is described that schedules silvicultural treatments for individual stands that are linked by multi-...

  7. The role of familiarity in binary choice inferences.

    PubMed

    Honda, Hidehito; Abe, Keiga; Matsuka, Toshihiko; Yamagishi, Kimihiko

    2011-07-01

    In research on the recognition heuristic (Goldstein & Gigerenzer, Psychological Review, 109, 75-90, 2002), knowledge of recognized objects has been categorized as "recognized" or "unrecognized" without regard to the degree of familiarity of the recognized object. In the present article, we propose a new inference model--familiarity-based inference. We hypothesize that when subjective knowledge levels (familiarity) of recognized objects differ, the degree of familiarity of recognized objects will influence inferences. Specifically, people are predicted to infer that the more familiar object in a pair of two objects has a higher criterion value on the to-be-judged dimension. In two experiments, using a binary choice task, we examined inferences about populations in a pair of two cities. Results support predictions of familiarity-based inference. Participants inferred that the more familiar city in a pair was more populous. Statistical modeling showed that individual differences in familiarity-based inference lie in the sensitivity to differences in familiarity. In addition, we found that familiarity-based inference can be generally regarded as an ecologically rational inference. Furthermore, when cue knowledge about the inference criterion was available, participants made inferences based on the cue knowledge about population instead of familiarity. Implications of the role of familiarity in psychological processes are discussed.

  8. Visual Recognition of the Elderly Concerning Risks of Falling or Stumbling Indoors in the Home

    PubMed Central

    Katsura, Toshiki; Miura, Norio; Hoshino, Akiko; Usui, Kanae; Takahashi, Yasuro; Hisamoto, Seiichi

    2011-01-01

    Objective: The objective of this study was to verify the recognition of dangers and obstacles within a house in the elderly when walking based on analyses of gaze point fixation. Materials and Methods: The rate of recognizing indoor dangers was compared among 30 elderly, 14 middle-aged and 11 young individuals using the Eye Mark Recorder. Results: 1) All of the elderly, middle-aged and young individuals showed a high recognition rate of 100% or near 100% when ascending outdoor steps but a low rate of recognizing obstacles placed on the steps. They showed a recognition rate of about 60% when descending steps from residential premises to the street. The rate of recognizing middle steps in the elderly was significantly lower than that in younger and middle-aged individuals. Regarding recognition indoors, when ascending stairs, all of the elderly, middle-aged and young individuals showed a high recognition rate of nearly 100%. When descending stairs, they showed a recognition rate of 70-90%. However, although the recognition rate in the elderly was lower than in younger and middle-aged individuals, no significant difference was observed. 2) When moving indoors, all of the elderly, middle-aged and young individuals showed a recognition rate of 70%-80%. The recognition rate was high regarding obstacles such as floors, televisions and chests of drawers but low for obstacles in the bathroom and steps on the path. The rate of recognizing steps of doorsills forming the division between a Japanese-style room and corridor as well as obstacles in a Japanese-style room was low, and the rate in the elderly was low, being 40% or less. Conclusion: The rate of recognizing steps of doorsills as well as obstacles in a Japanese-style room was lower in the elderly in comparison with middle-aged or young individuals. PMID:25648876

  9. Philosophical and Sociological Overview of Vocational Technical Education in Nigeria

    ERIC Educational Resources Information Center

    Kennedy, Odu Oji

    2012-01-01

    Vocational Technical Education is any kind of education which has the main purpose of preparing one for employment in recognized occupation. The foundation of vocational technical education is based on philosophy which was mainly established for self-employment and self-reliance of the individual(s) who partake in it. Viewing the philosophy and…

  10. Recognizing Faces Based on Inferred Traits in Autism Spectrum Disorders

    ERIC Educational Resources Information Center

    Ramachandran, Rajani; Mitchell, Peter; Ropar, Danielle

    2010-01-01

    Recent findings indicate that individuals with autism spectrum disorders (ASD) could, surprisingly, infer traits from behavioural descriptions. Now we need to know whether or not individuals with ASD are able to use trait information to identify people by their faces. In this study participants with and without ASD were presented with pairs of…

  11. Gender-Based Prototype Formation in Face Recognition

    ERIC Educational Resources Information Center

    Baudouin, Jean-Yves; Brochard, Renaud

    2011-01-01

    The role of gender categories in prototype formation during face recognition was investigated in 2 experiments. The participants were asked to learn individual faces and then to recognize them. During recognition, individual faces were mixed with faces, which were blended faces of same or different genders. The results of the 2 experiments showed…

  12. One Size Does Not Fit All.

    ERIC Educational Resources Information Center

    Newstrom, John W.; Lengnick-Hall, Mark L.

    1991-01-01

    The pedagogical model views trainees as passive recipients; andragogy assumes learner self-direction. A contingency approach to adult learning recognizes a need for individualized approaches based on an assessment of trainee characteristics. (SK)

  13. Brief Report: Teaching Situation-Based Emotions to Children with Autistic Spectrum Disorder

    ERIC Educational Resources Information Center

    McHugh, Louise; Bobarnac, Alina; Reed, Phil

    2011-01-01

    Many individuals with autism spectrum disorders (ASD) have difficulty recognizing emotions in themselves and others. Three children (all males) participated in the study. In a multi-element design children with ASD were trained to tact situation-based emotions (i.e., "happy", "sad", "angry", and "afraid") using novel video based scenarios. To…

  14. The U.S. draft guidance regarding population and individual bioequivalence approaches: comments by a research-based pharmaceutical company.

    PubMed

    Hauschke, D; Steinijans, V W

    2000-10-30

    Generally, the motivation for switching from average bioequivalence to population and/or individual bio-equivalence is well recognized in the light of certain limitations of the concept of average bioequivalence. However, this switch still results in unresolved issues which should be addressed before the regulatory guidance is finalized.

  15. EEG-based Affect and Workload Recognition in a Virtual Driving Environment for ASD Intervention

    PubMed Central

    Wade, Joshua W.; Key, Alexandra P.; Warren, Zachary E.; Sarkar, Nilanjan

    2017-01-01

    objective To build group-level classification models capable of recognizing affective states and mental workload of individuals with autism spectrum disorder (ASD) during driving skill training. Methods Twenty adolescents with ASD participated in a six-session virtual reality driving simulator based experiment, during which their electroencephalogram (EEG) data were recorded alongside driving events and a therapist’s rating of their affective states and mental workload. Five feature generation approaches including statistical features, fractal dimension features, higher order crossings (HOC)-based features, power features from frequency bands, and power features from bins (Δf = 2 Hz) were applied to extract relevant features. Individual differences were removed with a two-step feature calibration method. Finally, binary classification results based on the k-nearest neighbors algorithm and univariate feature selection method were evaluated by leave-one-subject-out nested cross-validation to compare feature types and identify discriminative features. Results The best classification results were achieved using power features from bins for engagement (0.95) and boredom (0.78), and HOC-based features for enjoyment (0.90), frustration (0.88), and workload (0.86). Conclusion Offline EEG-based group-level classification models are feasible for recognizing binary low and high intensity of affect and workload of individuals with ASD in the context of driving. However, while promising the applicability of the models in an online adaptive driving task requires further development. Significance The developed models provide a basis for an EEG-based passive brain computer interface system that has the potential to benefit individuals with ASD with an affect- and workload-based individualized driving skill training intervention. PMID:28422647

  16. The influence of same-sex marriage on the understanding of same-sex relationships.

    PubMed

    Lannutti, Pamela J

    2007-01-01

    This study examines the ways in which legally recognized same-sex marriage affects the understanding of same-sex romantic relationships for lesbian, gay, bisexual and transgendered (LGBT) individuals. Participants (N = 288) responded to an open-ended Web-based survey asking them to describe how legally recognized same-sex marriage influenced their view of their own romantic relationship or romantic relationships in general. Results indicate that legally recognized same-sex marriage impacted participants' understanding of romantic relationships by making existing relationships seem more real and by serving as a tool through which participants realized their desires for ideal potential partner and relationship characteristics. The results suggest that legally recognized same-sex marriage is seen as both beneficial and challenging for samesex couples.

  17. Occupational dermatitis in hairdressers - influence of individual and environmental factors.

    PubMed

    Carøe, Tanja K; Ebbehøj, Niels E; Agner, Tove

    2017-03-01

    Hairdressers are at risk of developing occupational contact dermatitis because of their intense contact with wet work in combination with chemicals. To perform an analysis of a cohort study of hairdressers with occupational contact dermatitis recognized in the period 2006-2011, focusing on individual and environmental factors associated with the disease. The study was a descriptive, register-based survey including all hairdressers with recognized occupational contact dermatitis in Denmark in the period January 2006 to September 2011. Data were obtained from the Danish National Board of Industrial Injuries. The study comprised 381 patients (373 women and 8 men). The median age was 25 years, 64.8% were apprentices, and 35.2% were fully trained hairdressers. The prevalence of atopic dermatitis was 36.0%, and was significantly higher among apprentices than among fully trained hairdressers (44.9% and 19.4%, respectively) (p < 0.001). Of the patients, 48.3% had their dermatitis recognized as occupational irritant contact dermatitis, 46.7% had their dermatitis recognized as as occupational allergic contact dermatitis or combined allergic and irritant contact dermatitis, and 5.0% were recognized as having occupational contact urticaria. The low median age, the high percentages of atopic dermatitis in apprentices and the fact that more apprentices than fully trained hairdressers had recognized occupational contact dermatitis underlines the importance of early prevention. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  18. Supporting the Health and Wellness of Individuals with Psychiatric Disabilities

    ERIC Educational Resources Information Center

    Swarbrick, Margaret; Nemec, Patricia B.

    2016-01-01

    Purpose: Psychiatric rehabilitation is recognized as a field with specialized knowledge and skills required for practice. The certified psychiatric rehabilitation practitioner (CPRP) credential, an exam-based certification process, is based on a regularly updated job task analysis that, in its most recent iteration, identified the new core…

  19. The SCERTS[TM] Model: A Comprehensive Educational Approach for Children with Autism Spectrum Disorders

    ERIC Educational Resources Information Center

    Prizant, Barry M.; Wetherby, Amy M.; Rubin, Emily; Laurent, Amy C.; Rydell, Patrick J.

    2005-01-01

    A groundbreaking synthesis of developmental, relationship-based, and skill-based approaches, The SCERTS[TM] Model provides a framework for improving communication and social-emotional abilities in individuals with autism spectrum disorders (ASD) and their families. Developed by internationally recognized experts, SCERTS[TM] supports developmental…

  20. The Role of the Physical Therapist and the Occupational Therapist in the School Setting. TIES: Therapy in Educational Settings. Revised.

    ERIC Educational Resources Information Center

    Hylton, Judith; And Others

    The manual aims to assist occupational and physical therapists in describing the differences between school-based therapy and clinic-based therapy, recognizing the primary role of school-based therapy in special education, identifying the therapist's responsibilities in the Individualized Education Program development process, describing the…

  1. Leaving a Print on Safety

    NASA Technical Reports Server (NTRS)

    2004-01-01

    Pattern-recognition technologies developed by NASA to identify spacecraft and other objects in space have helped in the development of new, biometrics-based security solutions on Earth that recognize individuals to grant access to protected facilities, equipment, or information.

  2. Face recognition in capuchin monkeys (Cebus apella).

    PubMed

    Pokorny, Jennifer J; de Waal, Frans B M

    2009-05-01

    Primates live in complex social groups that necessitate recognition of the individuals with whom they interact. In humans, faces provide a visual means by which to gain information such as identity, allowing us to distinguish between both familiar and unfamiliar individuals. The current study used a computerized oddity task to investigate whether a New World primate, Cebus apella, can discriminate the faces of In-group and Out-group conspecifics based on identity. The current study, improved on past methodologies, demonstrates that capuchins recognize the faces of both familiar and unfamiliar conspecifics. Once a performance criterion had been reached, subjects successfully transferred to a large number of novel images within the first 100 trials thus ruling out performance based on previous conditioning. Capuchins can be added to a growing list of primates that appear to recognize two-dimensional facial images of conspecifics. (PsycINFO Database Record (c) 2009 APA, all rights reserved).

  3. A triaxial accelerometer-based physical-activity recognition via augmented-signal features and a hierarchical recognizer.

    PubMed

    Khan, Adil Mehmood; Lee, Young-Koo; Lee, Sungyoung Y; Kim, Tae-Seong

    2010-09-01

    Physical-activity recognition via wearable sensors can provide valuable information regarding an individual's degree of functional ability and lifestyle. In this paper, we present an accelerometer sensor-based approach for human-activity recognition. Our proposed recognition method uses a hierarchical scheme. At the lower level, the state to which an activity belongs, i.e., static, transition, or dynamic, is recognized by means of statistical signal features and artificial-neural nets (ANNs). The upper level recognition uses the autoregressive (AR) modeling of the acceleration signals, thus, incorporating the derived AR-coefficients along with the signal-magnitude area and tilt angle to form an augmented-feature vector. The resulting feature vector is further processed by the linear-discriminant analysis and ANNs to recognize a particular human activity. Our proposed activity-recognition method recognizes three states and 15 activities with an average accuracy of 97.9% using only a single triaxial accelerometer attached to the subject's chest.

  4. Inclusive Instruction: Evidence-Based Practices for Teaching Students with Disabilities. What Works for Special-Needs Learners Series

    ERIC Educational Resources Information Center

    Brownell, Mary T.; Smith, Sean J.; Crockett, Jean B.; Griffin, Cynthia C.

    2012-01-01

    This accessible book presents research-based strategies for supporting K-8 students with high-incidence disabilities to become accomplished learners. The authors clearly describe the core components of effective inclusive instruction, showing how to recognize and respond to individual students' needs quickly and appropriately. Teachers are…

  5. Rhesus macaques recognize unique multi-modal face-voice relations of familiar individuals and not of unfamiliar ones

    PubMed Central

    Habbershon, Holly M.; Ahmed, Sarah Z.; Cohen, Yale E.

    2013-01-01

    Communication signals in non-human primates are inherently multi-modal. However, for laboratory-housed monkeys, there is relatively little evidence in support of the use of multi-modal communication signals in individual recognition. Here, we used a preferential-looking paradigm to test whether laboratory-housed rhesus could “spontaneously” (i.e., in the absence of operant training) use multi-modal communication stimuli to discriminate between known conspecifics. The multi-modal stimulus was a silent movie of two monkeys vocalizing and an audio file of the vocalization from one of the monkeys in the movie. We found that the gaze patterns of those monkeys that knew the individuals in the movie were reliably biased toward the individual that did not produce the vocalization. In contrast, there was not a systematic gaze pattern for those monkeys that did not know the individuals in the movie. These data are consistent with the hypothesis that laboratory-housed rhesus can recognize and distinguish between conspecifics based on auditory and visual communication signals. PMID:23774779

  6. 5 CFR 451.102 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Definitions. Award means something bestowed or an action taken to recognize and reward individual or team... to, employee incentives which are based on predetermined criteria such as productivity standards, performance goals, measurement systems, award formulas, or payout schedules. Award program means the specific...

  7. 5 CFR 451.102 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Definitions. Award means something bestowed or an action taken to recognize and reward individual or team... to, employee incentives which are based on predetermined criteria such as productivity standards, performance goals, measurement systems, award formulas, or payout schedules. Award program means the specific...

  8. 5 CFR 451.102 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Definitions. Award means something bestowed or an action taken to recognize and reward individual or team... to, employee incentives which are based on predetermined criteria such as productivity standards, performance goals, measurement systems, award formulas, or payout schedules. Award program means the specific...

  9. Identification of Diatraea spp. (Lepidoptera: Crambidae) based on cytochrome oxidase II.

    PubMed

    Barrera, Gloria Patricia; Villamizar, Laura Fernanda; Espinel, Carlos; Quintero, Edgar Mauricio; Belaich, Mariano Nicolás; Toloza, Deisy Liseth; Ghiringhelli, Pablo Daniel; Vargas, Germán

    2017-01-01

    Diatraea spp. (Lepidoptera: Crambidae) are a group of insects that are agriculture pests in many economically relevant crops such as sugarcane, sorghum, corn and rice. Recognized species for this genus respond differentially to natural enemies used in their biological control, emphasizing the importance of species in a regional approach. Currently, identification is based on the male genitalia. However, the availability of specimens collected from field and subjectivity based on the character recognition can seriously hamper species identification, and therefore result in inadequate pest management. To overcome this, individuals of Diatraea spp. preliminarily classified male genitalia and obtained from reared conditions and the field (both derived from natural populations occurring in Colombia) were analyzed using genitalic morphometry and molecular biology specifically using a fragment of the cytochrome oxidase subunit II (CO II) mitochondrial gene. Although morphometric analysis did not show any overriding results regarding genitalia morphology, the bioinformatics analyses of CO II sequences resulted in an adequate classification of the individuals within the recognized species. It also, revealed that the occurrence of clades associated with geographical distribution may be associated with cryptic species. The latter was also confirmed by a Single-Strand Conformation Polymorphism (SSCP) methodology evaluating the same fragment of CO II. This experimental approach allows properly recognizing each species and in consequence is proposed as an effective tool in Diatraea species identification.

  10. Identification of Diatraea spp. (Lepidoptera: Crambidae) based on cytochrome oxidase II

    PubMed Central

    Villamizar, Laura Fernanda; Espinel, Carlos; Quintero, Edgar Mauricio; Belaich, Mariano Nicolás; Toloza, Deisy Liseth

    2017-01-01

    Diatraea spp. (Lepidoptera: Crambidae) are a group of insects that are agriculture pests in many economically relevant crops such as sugarcane, sorghum, corn and rice. Recognized species for this genus respond differentially to natural enemies used in their biological control, emphasizing the importance of species in a regional approach. Currently, identification is based on the male genitalia. However, the availability of specimens collected from field and subjectivity based on the character recognition can seriously hamper species identification, and therefore result in inadequate pest management. To overcome this, individuals of Diatraea spp. preliminarily classified male genitalia and obtained from reared conditions and the field (both derived from natural populations occurring in Colombia) were analyzed using genitalic morphometry and molecular biology specifically using a fragment of the cytochrome oxidase subunit II (CO II) mitochondrial gene. Although morphometric analysis did not show any overriding results regarding genitalia morphology, the bioinformatics analyses of CO II sequences resulted in an adequate classification of the individuals within the recognized species. It also, revealed that the occurrence of clades associated with geographical distribution may be associated with cryptic species. The latter was also confirmed by a Single-Strand Conformation Polymorphism (SSCP) methodology evaluating the same fragment of CO II. This experimental approach allows properly recognizing each species and in consequence is proposed as an effective tool in Diatraea species identification. PMID:28873431

  11. Immunogenicity of Phleum pratense depigmented allergoid vaccines: experimental study in rabbits.

    PubMed

    Iraola, V; Gallego, M T; López-Matas, M A; Morales, M; Bel, I; García, N; Carnés, J

    2012-01-01

    Immunogenicity studies are based on accurate preclinical and clinical assessment of pharmaceutical products. The immunogenicity of modified allergen vaccines has not been fully elucidated, and the mechanisms involved are not well understood. Animal and human models have recently shown that depigmented allergoids induce specific immunoglobulin (Ig) G against individual allergens, thus supporting the clinical efficacy of these vaccines. The aim of this study was to investigate the production of specific IgG against individual antigens and their isoforms in rabbits injected with depigmented allergoid extracts of Phleum pratense pollen. Two New Zealand rabbits were immunized with depigmented-polymerized extracts adsorbed onto aluminum hydroxide (Depigoid) of P pratense. Rabbits were injected 3 times (35 microg Phl p 5). Specific IgG titers against native, depigmented, and depigmented-polymerized extracts and individual allergens (rPhl p 1 and rPhl p 5a) were analyzed by direct enzyme-linked immunosorbent assay. The capacity of these synthesized antibodies to recognize individual native and depigmented allergens and different isoforms was evaluated by immunoblot and 2-D analysis. All rabbits produced high titers of specific IgG against the 3 extracts. Rabbits injected with depigmented allergoids produced similar specific antibody titers against native, depigmented, and depigmented-polymerized extracts. Serum samples recognized individual allergens and their isoforms in the nonmodified extracts. Vaccines containing depigmented allergoid extracts of P pratense induce immunogenicity in vivo. The antibodies produced after injection of these extracts clearly recognized allergens and different isoforms in their native configuration.

  12. Recognition of chemical entities: combining dictionary-based and grammar-based approaches.

    PubMed

    Akhondi, Saber A; Hettne, Kristina M; van der Horst, Eelke; van Mulligen, Erik M; Kors, Jan A

    2015-01-01

    The past decade has seen an upsurge in the number of publications in chemistry. The ever-swelling volume of available documents makes it increasingly hard to extract relevant new information from such unstructured texts. The BioCreative CHEMDNER challenge invites the development of systems for the automatic recognition of chemicals in text (CEM task) and for ranking the recognized compounds at the document level (CDI task). We investigated an ensemble approach where dictionary-based named entity recognition is used along with grammar-based recognizers to extract compounds from text. We assessed the performance of ten different commercial and publicly available lexical resources using an open source indexing system (Peregrine), in combination with three different chemical compound recognizers and a set of regular expressions to recognize chemical database identifiers. The effect of different stop-word lists, case-sensitivity matching, and use of chunking information was also investigated. We focused on lexical resources that provide chemical structure information. To rank the different compounds found in a text, we used a term confidence score based on the normalized ratio of the term frequencies in chemical and non-chemical journals. The use of stop-word lists greatly improved the performance of the dictionary-based recognition, but there was no additional benefit from using chunking information. A combination of ChEBI and HMDB as lexical resources, the LeadMine tool for grammar-based recognition, and the regular expressions, outperformed any of the individual systems. On the test set, the F-scores were 77.8% (recall 71.2%, precision 85.8%) for the CEM task and 77.6% (recall 71.7%, precision 84.6%) for the CDI task. Missed terms were mainly due to tokenization issues, poor recognition of formulas, and term conjunctions. We developed an ensemble system that combines dictionary-based and grammar-based approaches for chemical named entity recognition, outperforming any of the individual systems that we considered. The system is able to provide structure information for most of the compounds that are found. Improved tokenization and better recognition of specific entity types is likely to further improve system performance.

  13. Recognition of chemical entities: combining dictionary-based and grammar-based approaches

    PubMed Central

    2015-01-01

    Background The past decade has seen an upsurge in the number of publications in chemistry. The ever-swelling volume of available documents makes it increasingly hard to extract relevant new information from such unstructured texts. The BioCreative CHEMDNER challenge invites the development of systems for the automatic recognition of chemicals in text (CEM task) and for ranking the recognized compounds at the document level (CDI task). We investigated an ensemble approach where dictionary-based named entity recognition is used along with grammar-based recognizers to extract compounds from text. We assessed the performance of ten different commercial and publicly available lexical resources using an open source indexing system (Peregrine), in combination with three different chemical compound recognizers and a set of regular expressions to recognize chemical database identifiers. The effect of different stop-word lists, case-sensitivity matching, and use of chunking information was also investigated. We focused on lexical resources that provide chemical structure information. To rank the different compounds found in a text, we used a term confidence score based on the normalized ratio of the term frequencies in chemical and non-chemical journals. Results The use of stop-word lists greatly improved the performance of the dictionary-based recognition, but there was no additional benefit from using chunking information. A combination of ChEBI and HMDB as lexical resources, the LeadMine tool for grammar-based recognition, and the regular expressions, outperformed any of the individual systems. On the test set, the F-scores were 77.8% (recall 71.2%, precision 85.8%) for the CEM task and 77.6% (recall 71.7%, precision 84.6%) for the CDI task. Missed terms were mainly due to tokenization issues, poor recognition of formulas, and term conjunctions. Conclusions We developed an ensemble system that combines dictionary-based and grammar-based approaches for chemical named entity recognition, outperforming any of the individual systems that we considered. The system is able to provide structure information for most of the compounds that are found. Improved tokenization and better recognition of specific entity types is likely to further improve system performance. PMID:25810767

  14. Self-Reported Discrimination in Health-Care Settings Based on Recognizability as Transgender: A Cross-Sectional Study Among Transgender U.S. Citizens.

    PubMed

    Rodriguez, Amanda; Agardh, Anette; Asamoah, Benedict Oppong

    2018-05-01

    Discrimination has long been tied to health inequality. Rejected by families and communities because of their gender identity and gender-role behavior, transgender individuals are often socially marginalized. This study aimed to assess discrimination in health-care settings among persons self-identifying as transgender in the U.S. in relation to their recognizability as transgender, operationalized as how often they experienced that others recognized them as transgender. Data were obtained from the National Transgender Discrimination Survey (n = 6106 participants, assigned sex at birth = 3608 males, 2480 females, respectively). Binary logistic regressions were performed to examine associations between transgender recognizability and discrimination in health-care settings. Being recognized as transgender to any extent had a significant effect on perceived discrimination in health care. Always recognized as transgender showed significant associations with discrimination in a health-care setting (OR 1.48) and the following individualized health-care settings: social service settings (rape crisis and domestic violence centers, OR 5.22) and mental health settings (mental health clinic and drug treatment program, OR 1.87). Sex work and other street economy, which are known experiential factors affected by discrimination, were also significantly associated with discrimination in health-care settings. Discrimination in health-care settings is pervasive for transgender who are recognized as transgender. Public health efforts to improve access to equitable health care for transgender individuals may benefit from consideration of demographic, experiential, and medical risk factors to more fully understand the source of the seemingly excess risk of discrimination among persons recognized by others as being transgender.

  15. [Sex differentiation in plants. Terms and notions].

    PubMed

    Godin, V N

    2007-01-01

    There are two methodological approaches to the study of sex in plants: the descriptive and morphological approach and the quantitative approach. The former is based exclusively on external morphological peculiarities of the generative organs of the flower, the latter is based on the functioning of individuals as parents of the coming generation. It has been suggested to recognize three flower types: staminate, pistillate, and complete. Depending on the distribution pattern of the flowers of different sex type, there are monomorphic populations (all individuals form flowers of the same type) and heteromorphic populations (individuals have flowers of different types). Monomorphic populations include monoclinous, monoecious, gynomonoecious, andromonoecious, and polygamomonoecious ones. Among heteromorphic populations, dioecious, polygamodioecious, subdioecious, paradioecious, and trioecious ones are recognized. It is desirable to give up the usage of such terms as "bisexual", "polygamous", "functionally female", and "functionally male" flowers, "temporary dioecy" and some others. The notion "gender" has been established in English-language works for describing the sex quantitavely; two additional terms have been proposed: "phenotypic gender" and "functional gender". The recently developed quantitative approach is at present in the process of accumulating material, and in need of the further elaborating the methodological base for research. Analysis of the principal notions shows the necessity to form their integrated structure and to correct the usage of the existing and new terms.

  16. Personalized Medicine in a New Genomic Era: Ethical and Legal Aspects.

    PubMed

    Shoaib, Maria; Rameez, Mansoor Ali Merchant; Hussain, Syed Ather; Madadin, Mohammed; Menezes, Ritesh G

    2017-08-01

    The genome of two completely unrelated individuals is quite similar apart from minor variations called single nucleotide polymorphisms which contribute to the uniqueness of each and every person. These single nucleotide polymorphisms are of great interest clinically as they are useful in figuring out the susceptibility of certain individuals to particular diseases and for recognizing varied responses to pharmacological interventions. This gives rise to the idea of 'personalized medicine' as an exciting new therapeutic science in this genomic era. Personalized medicine suggests a unique treatment strategy based on an individual's genetic make-up. Its key principles revolve around applied pharmaco-genomics, pharmaco-kinetics and pharmaco-proteomics. Herein, the ethical and legal aspects of personalized medicine in a new genomic era are briefly addressed. The ultimate goal is to comprehensively recognize all relevant forms of genetic variation in each individual and be able to interpret this information in a clinically meaningful manner within the ambit of ethical and legal considerations. The authors of this article firmly believe that personalized medicine has the potential to revolutionize the current landscape of medicine as it makes its way into clinical practice.

  17. Evidence-based practice of periodontics.

    PubMed

    Cobb, Charles M; MacNeill, Simon R; Satheesh, Keerthana

    2010-01-01

    Evidence-based practice involves complex and conscientious decision making based not only on the available evidence but also on patient characteristics, situations, and preferences. It recognizes that care is individualized and ever-changing and involves uncertainties and probabilities. The specialty of periodontics has abundant high-level evidence upon which treatment decisions can be determined. This paper offers a brief commentary and overview of the available evidence commonly used in the private practice of periodontics.

  18. Distinguishing Individual DNA Bases in a Network by Non-Resonant Tip-Enhanced Raman Scattering.

    PubMed

    Zhang, Rui; Zhang, Xianbiao; Wang, Huifang; Zhang, Yao; Jiang, Song; Hu, Chunrui; Zhang, Yang; Luo, Yi; Dong, Zhenchao

    2017-05-08

    The importance of identifying DNA bases at the single-molecule level is well recognized for many biological applications. Although such identification can be achieved by electrical measurements using special setups, it is still not possible to identify single bases in real space by optical means owing to the diffraction limit. Herein, we demonstrate the outstanding ability of scanning tunneling microscope (STM)-controlled non-resonant tip-enhanced Raman scattering (TERS) to unambiguously distinguish two individual complementary DNA bases (adenine and thymine) with a spatial resolution down to 0.9 nm. The distinct Raman fingerprints identified for the two molecules allow to differentiate in real space individual DNA bases in coupled base pairs. The demonstrated ability of non-resonant Raman scattering with super-high spatial resolution will significantly extend the applicability of TERS, opening up new routes for single-molecule DNA sequencing. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. Empirical testing AOP network-based hazard prediction combined effect of aromatase inhibition & androgen receptor agonism

    EPA Science Inventory

    Adverse outcome pathways (AOPs) describe linkages between a specific molecular perturbation resulting from interaction of a chemical with a biomolecule in an organism and one possible adverse outcome of regulatory significance. While individual AOPs have utility, it is recognized...

  20. Essential Use Cases for Pedagogical Patterns

    ERIC Educational Resources Information Center

    Derntl, Michael; Botturi, Luca

    2006-01-01

    Coming from architecture, through computer science, pattern-based design spread into other disciplines and is nowadays recognized as a powerful way of capturing and reusing effective design practice. However, current pedagogical pattern approaches lack widespread adoption, both by users and authors, and are still limited to individual initiatives.…

  1. The Unfinished Agenda.

    ERIC Educational Resources Information Center

    Phillips, Madge

    1981-01-01

    Items on the unfinished agendas of society, education, and physical education include: (1) the war on human suffering; (2) the paradox of education as the equalizer of social differences, although it recognizes individual merit based on academic excellence; and (3) physical education as an agent of social change and responsibility. (JN)

  2. A new look at emotion perception: Concepts speed and shape facial emotion recognition.

    PubMed

    Nook, Erik C; Lindquist, Kristen A; Zaki, Jamil

    2015-10-01

    Decades ago, the "New Look" movement challenged how scientists thought about vision by suggesting that conceptual processes shape visual perceptions. Currently, affective scientists are likewise debating the role of concepts in emotion perception. Here, we utilized a repetition-priming paradigm in conjunction with signal detection and individual difference analyses to examine how providing emotion labels-which correspond to discrete emotion concepts-affects emotion recognition. In Study 1, pairing emotional faces with emotion labels (e.g., "sad") increased individuals' speed and sensitivity in recognizing emotions. Additionally, individuals with alexithymia-who have difficulty labeling their own emotions-struggled to recognize emotions based on visual cues alone, but not when emotion labels were provided. Study 2 replicated these findings and further demonstrated that emotion concepts can shape perceptions of facial expressions. Together, these results suggest that emotion perception involves conceptual processing. We discuss the implications of these findings for affective, social, and clinical psychology. (c) 2015 APA, all rights reserved).

  3. Can Neurotypical Individuals Read Autistic Facial Expressions? Atypical Production of Emotional Facial Expressions in Autism Spectrum Disorders

    PubMed Central

    Biotti, Federica; Catmur, Caroline; Press, Clare; Happé, Francesca; Cook, Richard; Bird, Geoffrey

    2015-01-01

    The difficulties encountered by individuals with autism spectrum disorder (ASD) when interacting with neurotypical (NT, i.e. nonautistic) individuals are usually attributed to failure to recognize the emotions and mental states of their NT interaction partner. It is also possible, however, that at least some of the difficulty is due to a failure of NT individuals to read the mental and emotional states of ASD interaction partners. Previous research has frequently observed deficits of typical facial emotion recognition in individuals with ASD, suggesting atypical representations of emotional expressions. Relatively little research, however, has investigated the ability of individuals with ASD to produce recognizable emotional expressions, and thus, whether NT individuals can recognize autistic emotional expressions. The few studies which have investigated this have used only NT observers, making it impossible to determine whether atypical representations are shared among individuals with ASD, or idiosyncratic. This study investigated NT and ASD participants’ ability to recognize emotional expressions produced by NT and ASD posers. Three posing conditions were included, to determine whether potential group differences are due to atypical cognitive representations of emotion, impaired understanding of the communicative value of expressions, or poor proprioceptive feedback. Results indicated that ASD expressions were recognized less well than NT expressions, and that this is likely due to a genuine deficit in the representation of typical emotional expressions in this population. Further, ASD expressions were equally poorly recognized by NT individuals and those with ASD, implicating idiosyncratic, rather than common, atypical representations of emotional expressions in ASD. Autism Res 2016, 9: 262–271. © 2015 International Society for Autism Research, Wiley Periodicals, Inc. PMID:26053037

  4. Kin recognition in zebrafish: a 24-hour window for olfactory imprinting

    PubMed Central

    Gerlach, Gabriele; Hodgins-Davis, Andrea; Avolio, Carla; Schunter, Celia

    2008-01-01

    Distinguishing kin from non-kin profoundly impacts the evolution of social behaviour. Individuals able to assess the genetic relatedness of conspecifics can preferentially allocate resources towards related individuals and avoid inbreeding. We have addressed the question of how animals acquire the ability to recognize kin by studying the development of olfactory kin preference in zebrafish (Danio rerio). Previously, we showed that zebrafish use an olfactory template to recognize even unfamiliar kin through phenotype matching. Here, we show for the first time that this phenotype matching is based on a learned olfactory imprinting process in which exposure to kin individuals on day 6 post fertilization (pf) is necessary and sufficient for imprinting. Larvae that were exposed to kin before or after but not on day 6 pf did not recognize kin. Larvae isolated from all contact with conspecifics did not imprint on their own chemical cues; therefore, we see no evidence for kin recognition through self-matching in this species. Surprisingly, exposure to non-kin odour during the sensitive phase of development did not result in imprinting on the odour cues of unrelated individuals, suggesting a genetic predisposition to kin odour. Urine-born peptides expressed by genes of the immune system (MHC) are important messengers carrying information about ‘self’ and ‘other’. We suggest that phenotype matching is acquired through a time-sensitive learning process that, in zebrafish, includes a genetic predisposition potentially involving MHC genes expressed in the olfactory receptor neurons. PMID:18544507

  5. Kin recognition in zebrafish: a 24-hour window for olfactory imprinting.

    PubMed

    Gerlach, Gabriele; Hodgins-Davis, Andrea; Avolio, Carla; Schunter, Celia

    2008-09-22

    Distinguishing kin from non-kin profoundly impacts the evolution of social behaviour. Individuals able to assess the genetic relatedness of conspecifics can preferentially allocate resources towards related individuals and avoid inbreeding. We have addressed the question of how animals acquire the ability to recognize kin by studying the development of olfactory kin preference in zebrafish (Danio rerio). Previously, we showed that zebrafish use an olfactory template to recognize even unfamiliar kin through phenotype matching. Here, we show for the first time that this phenotype matching is based on a learned olfactory imprinting process in which exposure to kin individuals on day 6 post fertilization (pf) is necessary and sufficient for imprinting. Larvae that were exposed to kin before or after but not on day 6 pf did not recognize kin. Larvae isolated from all contact with conspecifics did not imprint on their own chemical cues; therefore, we see no evidence for kin recognition through self-matching in this species. Surprisingly, exposure to non-kin odour during the sensitive phase of development did not result in imprinting on the odour cues of unrelated individuals, suggesting a genetic predisposition to kin odour. Urine-born peptides expressed by genes of the immune system (MHC) are important messengers carrying information about 'self' and 'other'. We suggest that phenotype matching is acquired through a time-sensitive learning process that, in zebrafish, includes a genetic predisposition potentially involving MHC genes expressed in the olfactory receptor neurons.

  6. Rebuilding the Marriage during Recovery from Compulsive Sexual Behavior.

    ERIC Educational Resources Information Center

    Schneider, Jennifer P.

    1989-01-01

    Defines sexual addiction and describes its effects on individual and his/her primary relationship. Addresses problems of recognizing sexual compulsivity and offers suggestions for treatment which include use of both dyadic and group therapy. Recommends attendance at self-help groups based on Alcoholics Anonymous model. (Author/CM)

  7. Broadening the Conceptualization of Literacy in the Lives of Adults with Intellectual Disability

    ERIC Educational Resources Information Center

    Morgan, Michelle F.; Cuskelly, Monica; Moni, Karen B.

    2011-01-01

    Current pedagogical approaches recognize literacy as a social practice and yet school-based conceptualizations continue to dominate understandings of literacy learning of individuals with intellectual disability. Such understandings lead to local or everyday literacy practices being devalued and overlooked. Thus, for adults with intellectual…

  8. Building Relationships through Exchange

    ERIC Educational Resources Information Center

    Primavera, Angi; Hall, Ellen

    2011-01-01

    From the moment of birth, children form and develop relationships with others in their world based on exchange. Children recognize that engaging in such encounters offers them the opportunity to enter into a relationship with another individual and to nurture that relationship through the exchange of messages and gifts, items and ideas. At Boulder…

  9. Forest Service Log Grades for Southern Pine

    Treesearch

    Robert A. Campbell

    1964-01-01

    Wood users have long recognized and evaluated differences in timber quality of southern pine. However, the many concepts of quality were based largely on individual experience. This varied concept of timber quality and the absence of a general system or systems for measuring it existed until the 1930's.

  10. STREAM: A First Programming Process

    ERIC Educational Resources Information Center

    Caspersen, Michael E.; Kolling, Michael

    2009-01-01

    Programming is recognized as one of seven grand challenges in computing education. Decades of research have shown that the major problems novices experience are composition-based---they may know what the individual programming language constructs are, but they do not know how to put them together. Despite this fact, textbooks, educational…

  11. Evaluation Capacity Building: Can a Classroom-Based Course Make a Difference?

    ERIC Educational Resources Information Center

    Kaye-Tzadok, Avital; Spiro, Shimon E.

    2016-01-01

    Purpose: Growing emphasis on program and practice evaluation in social work education coalesces with a growing interest in evaluation capacity building (ECB) within the interdisciplinary field of evaluation. However, the literature on ECB, while recognizing the importance of imparting knowledge and skills to individuals, largely ignores the…

  12. Histopathological image analysis of chemical-induced hepatocellular hypertrophy in mice.

    PubMed

    Asaoka, Yoshiji; Togashi, Yuko; Mutsuga, Mayu; Imura, Naoko; Miyoshi, Tomoya; Miyamoto, Yohei

    2016-04-01

    Chemical-induced hepatocellular hypertrophy is frequently observed in rodents, and is mostly caused by the induction of phase I and phase II drug metabolic enzymes and peroxisomal lipid metabolic enzymes. Liver weight is a sensitive and commonly used marker for detecting hepatocellular hypertrophy, but is also increased by a number of other factors. Histopathological observations subjectively detect changes such as hepatocellular hypertrophy based on the size of a hepatocyte. Therefore, quantitative microscopic observations are required to evaluate histopathological alterations objectively. In the present study, we developed a novel quantitative method for an image analysis of hepatocellular hypertrophy using liver sections stained with hematoxylin and eosin, and demonstrated its usefulness for evaluating hepatocellular hypertrophy induced by phenobarbital (a phase I and phase II enzyme inducer) and clofibrate (a peroxisomal enzyme inducer) in mice. The algorithm of this imaging analysis was designed to recognize an individual hepatocyte through a combination of pixel-based and object-based analyses. Hepatocellular nuclei and the surrounding non-hepatocellular cells were recognized by the pixel-based analysis, while the areas of the recognized hepatocellular nuclei were then expanded until they ran against their expanding neighboring hepatocytes and surrounding non-hepatocellular cells by the object-based analysis. The expanded area of each hepatocellular nucleus was regarded as the size of an individual hepatocyte. The results of this imaging analysis showed that changes in the sizes of hepatocytes corresponded with histopathological observations in phenobarbital and clofibrate-treated mice, and revealed a correlation between hepatocyte size and liver weight. In conclusion, our novel image analysis method is very useful for quantitative evaluations of chemical-induced hepatocellular hypertrophy. Copyright © 2015 Elsevier GmbH. All rights reserved.

  13. Male tawny dragons use throat patterns to recognize rivals.

    PubMed

    Osborne, Louise; Umbers, Kate D L; Backwell, Patricia R Y; Keogh, J Scott

    2012-10-01

    The ability to distinguish between familiar and unfamiliar conspecifics is important for many animals, especially territorial species since it allows them to avoid unnecessary interactions with individuals that pose little threat. There are very few studies, however, that identify the proximate cues that facilitate such recognition in visual systems. Here, we show that in tawny dragons (Ctenophorus decresii), males can recognize familiar and unfamiliar conspecific males based on morphological features alone, without the aid of chemical or behavioural cues. We further show that it is the colour pattern of the throat patches (gular) that facilitates this recognition.

  14. Quantum neural network based machine translator for Hindi to English.

    PubMed

    Narayan, Ravi; Singh, V P; Chakraverty, S

    2014-01-01

    This paper presents the machine learning based machine translation system for Hindi to English, which learns the semantically correct corpus. The quantum neural based pattern recognizer is used to recognize and learn the pattern of corpus, using the information of part of speech of individual word in the corpus, like a human. The system performs the machine translation using its knowledge gained during the learning by inputting the pair of sentences of Devnagri-Hindi and English. To analyze the effectiveness of the proposed approach, 2600 sentences have been evaluated during simulation and evaluation. The accuracy achieved on BLEU score is 0.7502, on NIST score is 6.5773, on ROUGE-L score is 0.9233, and on METEOR score is 0.5456, which is significantly higher in comparison with Google Translation and Bing Translation for Hindi to English Machine Translation.

  15. African Americans, democracy, and biomedical and behavioral research: contradictions or consensus in community-based participatory research?

    PubMed

    Spigner, C

    Individualism, in both its political and attitudinal senses, reinforces societal and institutional racism in the United States. Because of individualism's dominant focus on self-interest and self-reliance, any application of "participatory democracy" in community-based biomedical and behavioral research is fraught with dilemmas similar to those that Gunnar Myrdal observed between American racism and democracy. The research establishment is overwhelmed by well-meaning non-minorities who recognize racism and its consequences in health, but only greater representation of people-of-color in the health establishment can ameliorate the inherent contradictions of "participatory democracy" which is so fundamental to the process of community-based participatory research.

  16. Long-term recognition memory of individual conspecifics is associated with telencephalic expression of Egr-1 in the electric fish Apteronotus leptorhynchus.

    PubMed

    Harvey-Girard, Erik; Tweedle, Jessica; Ironstone, Joel; Cuddy, Martin; Ellis, William; Maler, Leonard

    2010-07-15

    Primates and songbirds can learn to recognize individual conspecifics based on complex sensory cues; this requires a large, highly differentiated dorsal telencephalon. Here we show that the electric fish Apteronotus leptorhynchus can learn to recognize individual conspecifics based on a simple cue, the beat frequency of their summed sinusoidal electric organ discharges (EOD). Male fish produce transient communication signals (chirps) in response to mimic EODs. The chirp response habituates over repeated stimulus presentations within one experimental session, continues to habituate over successive daily sessions and is nearly extinguished after 5-7 days. Habituation of the chirp response was specific to the presented beat frequency. The conversion of short- to long-term habituation could be disrupted by cooling the head 30 minutes after the daily habituation trials. Consolidation of long-term memory in mammals is thought to involve induced expression of an immediate early gene, Egr-1. We cloned the Apteronotid homolog of the Egr-1 gene and found that chirp-evoking stimuli induced strong expression of its mRNA within the dorsal (Dd), central (DC), and lateral (DL) subdivisions of the dorsal telencephalon. Interestingly, the dorsolateral region is hypothesized to be homologous to the amniote hippocampal formation. We conclude that A. leptorhynchus can learn to identify individual conspecifics based on their EOD frequency and can remember these frequencies for several days. We hypothesize that this form of learning, as in primates and songbirds, requires a subset of dorsal telencephalic areas and involves a consolidation-like process that includes the expression of the transcription factor AptEgr-1.

  17. Integrating Model-Driven and Data-Driven Techniques for Analyzing Learning Behaviors in Open-Ended Learning Environments

    ERIC Educational Resources Information Center

    Kinnebrew, John S.; Segedy, James R.; Biswas, Gautam

    2017-01-01

    Research in computer-based learning environments has long recognized the vital role of adaptivity in promoting effective, individualized learning among students. Adaptive scaffolding capabilities are particularly important in open-ended learning environments, which provide students with opportunities for solving authentic and complex problems, and…

  18. An Expert System-based Context-Aware Ubiquitous Learning Approach for Conducting Science Learning Activities

    ERIC Educational Resources Information Center

    Wu, Po-Han; Hwang, Gwo-Jen; Tsai, Wen-Hung

    2013-01-01

    Context-aware ubiquitous learning has been recognized as being a promising approach that enables students to interact with real-world learning targets with supports from the digital world. Several researchers have indicated the importance of providing learning guidance or hints to individual students during the context-aware ubiquitous learning…

  19. Diana's Eulogy: Breaking New Ground in Epideictic Rhetoric?

    ERIC Educational Resources Information Center

    Scott, David K.

    A speech in response to an individual's death is by nature a recurring form of rhetoric. Based on audience expectations and needs, certain generic aspects have emerged to characterize eulogies. The funeral oration has generally been recognized as a form of epideictic rhetoric. Modern scholars have generally broadly defined epideictic rhetoric to…

  20. Prepping Our Teachers for Teaching as a Profession

    ERIC Educational Resources Information Center

    Darling-Hammond, Linda

    2005-01-01

    Around the world, the importance of education to individual and societal success has increased at a breathtaking pace as a new knowledge-based economy has emerged. As a consequence, most countries have been engaged in intensive reforms of their education systems, and many have focused especially on improving teacher education, recognizing that…

  1. Deposition from ground-based sprays of carbaryl to protect individual trees from bark beetle attack in the western United States

    Treesearch

    C.J. Fettig; A.S. Munson; S.R. McKelvey; DeGomez T.E.

    2009-01-01

    Bark beetles are commonly recognized as important tree mortality agents in western coniferous forests, but relatively few species (<25) are capable of killing apparently-healthy trees. However, during the last decade extensive levels of tree mortality were attributed to bark beetle outbreaks in...

  2. Individual differences in perceiving and recognizing faces-One element of social cognition.

    PubMed

    Wilhelm, Oliver; Herzmann, Grit; Kunina, Olga; Danthiir, Vanessa; Schacht, Annekathrin; Sommer, Werner

    2010-09-01

    Recognizing faces swiftly and accurately is of paramount importance to humans as a social species. Individual differences in the ability to perform these tasks may therefore reflect important aspects of social or emotional intelligence. Although functional models of face cognition based on group and single case studies postulate multiple component processes, little is known about the ability structure underlying individual differences in face cognition. In 2 large individual differences experiments (N = 151 and N = 209), a broad variety of face-cognition tasks were tested and the component abilities of face cognition-face perception, face memory, and the speed of face cognition-were identified and then replicated. Experiment 2 also showed that the 3 face-cognition abilities are clearly distinct from immediate and delayed memory, mental speed, general cognitive ability, and object cognition. These results converge with functional and neuroanatomical models of face cognition by demonstrating the difference between face perception and face memory. The results also underline the importance of distinguishing between speed and accuracy of face cognition. Together our results provide a first step toward establishing face-processing abilities as an independent ability reflecting elements of social intelligence. (PsycINFO Database Record (c) 2010 APA, all rights reserved).

  3. Recognition of pornographic web pages by classifying texts and images.

    PubMed

    Hu, Weiming; Wu, Ou; Chen, Zhouyao; Fu, Zhouyu; Maybank, Steve

    2007-06-01

    With the rapid development of the World Wide Web, people benefit more and more from the sharing of information. However, Web pages with obscene, harmful, or illegal content can be easily accessed. It is important to recognize such unsuitable, offensive, or pornographic Web pages. In this paper, a novel framework for recognizing pornographic Web pages is described. A C4.5 decision tree is used to divide Web pages, according to content representations, into continuous text pages, discrete text pages, and image pages. These three categories of Web pages are handled, respectively, by a continuous text classifier, a discrete text classifier, and an algorithm that fuses the results from the image classifier and the discrete text classifier. In the continuous text classifier, statistical and semantic features are used to recognize pornographic texts. In the discrete text classifier, the naive Bayes rule is used to calculate the probability that a discrete text is pornographic. In the image classifier, the object's contour-based features are extracted to recognize pornographic images. In the text and image fusion algorithm, the Bayes theory is used to combine the recognition results from images and texts. Experimental results demonstrate that the continuous text classifier outperforms the traditional keyword-statistics-based classifier, the contour-based image classifier outperforms the traditional skin-region-based image classifier, the results obtained by our fusion algorithm outperform those by either of the individual classifiers, and our framework can be adapted to different categories of Web pages.

  4. Facial Asymmetry-Based Age Group Estimation: Role in Recognizing Age-Separated Face Images.

    PubMed

    Sajid, Muhammad; Taj, Imtiaz Ahmad; Bajwa, Usama Ijaz; Ratyal, Naeem Iqbal

    2018-04-23

    Face recognition aims to establish the identity of a person based on facial characteristics. On the other hand, age group estimation is the automatic calculation of an individual's age range based on facial features. Recognizing age-separated face images is still a challenging research problem due to complex aging processes involving different types of facial tissues, skin, fat, muscles, and bones. Certain holistic and local facial features are used to recognize age-separated face images. However, most of the existing methods recognize face images without incorporating the knowledge learned from age group estimation. In this paper, we propose an age-assisted face recognition approach to handle aging variations. Inspired by the observation that facial asymmetry is an age-dependent intrinsic facial feature, we first use asymmetric facial dimensions to estimate the age group of a given face image. Deeply learned asymmetric facial features are then extracted for face recognition using a deep convolutional neural network (dCNN). Finally, we integrate the knowledge learned from the age group estimation into the face recognition algorithm using the same dCNN. This integration results in a significant improvement in the overall performance compared to using the face recognition algorithm alone. The experimental results on two large facial aging datasets, the MORPH and FERET sets, show that the proposed age group estimation based on the face recognition approach yields superior performance compared to some existing state-of-the-art methods. © 2018 American Academy of Forensic Sciences.

  5. Music therapy services for individuals with autism spectrum disorder: a survey of clinical practices and training needs.

    PubMed

    Kern, Petra; Rivera, Nicole R; Chandler, Alie; Humpal, Marcia

    2013-01-01

    Over the past decade, the definitions, diagnoses, prevalence rates, theories about the causes, evidence-based treatment options, and practice guidelines pertaining to Autism Spectrum Disorder (ASD) have undergone numerous changes. While several recent studies evaluate the effects of music therapy interventions for individuals with ASD, no current review reflects the latest music therapy practices and trends. The purpose of this study was to evaluate the status of music therapy practices for serving clients with ASD, the implementation of national ASD standards and guidelines, the awareness of recent developments, and training needs of music therapists. Professional members of the American Music Therapy Association who are working with individuals with ASD served as the sample for this national cross-sectional survey study (N = 328). A 45-item online questionnaire was designed and distributed through email and social media. Participants accessed the online survey through SurveyMonkey®. Findings suggest music therapy practices and services for individuals with ASD have shifted and now reflect a slightly higher percentage of caseload, a broader age range of clients, and a trend to serve clients in home and community settings. Most therapeutic processes align with recommended practices for ASD and incorporate several of the recognized evidence-based practices. Less understood or recognized are inclusion practices and latest developments in the field of ASD. Music therapists have a solid understanding of providing services for individuals with ASD, but would benefit from advanced online training and improved information dissemination to stay current with the rapidly changing aspects pertinent to this population. © 2013 by the American Music Therapy Association.

  6. Quantum Neural Network Based Machine Translator for Hindi to English

    PubMed Central

    Singh, V. P.; Chakraverty, S.

    2014-01-01

    This paper presents the machine learning based machine translation system for Hindi to English, which learns the semantically correct corpus. The quantum neural based pattern recognizer is used to recognize and learn the pattern of corpus, using the information of part of speech of individual word in the corpus, like a human. The system performs the machine translation using its knowledge gained during the learning by inputting the pair of sentences of Devnagri-Hindi and English. To analyze the effectiveness of the proposed approach, 2600 sentences have been evaluated during simulation and evaluation. The accuracy achieved on BLEU score is 0.7502, on NIST score is 6.5773, on ROUGE-L score is 0.9233, and on METEOR score is 0.5456, which is significantly higher in comparison with Google Translation and Bing Translation for Hindi to English Machine Translation. PMID:24977198

  7. Reading with a Purpose: Communicative Reading Tasks for the Foreign Language Classroom. ERIC Digest.

    ERIC Educational Resources Information Center

    Knutson, Elizabeth M.

    In describing reading proficiency--the relative difficulty or ease that an individual reader experiences reading a particular text--researchers have recognized the importance of both text- and reader-based factors. This digest focuses on the factor of purpose, as determined by the reader or the instructional context. Having a purpose means having…

  8. Toward a Critical Pedagogy of Engagement for Alienated Youth: Insights from Freire and School-Based Research

    ERIC Educational Resources Information Center

    McInerney, Peter

    2009-01-01

    Although alienation is widely recognized as a barrier to educational success for many students, prevailing explanations tend to focus on psychological traits and individual deficits, rather than the oppressive economic and social structures bearing down on young people. This paper addresses the issues of youth alienation and student engagement…

  9. Role-Based And Adaptive User Interface Designs In A Teledermatology Consult System: A Way To Secure And A Way To Enhance

    PubMed Central

    Lin, Yi-Jung; Speedie, Stuart

    2003-01-01

    User interface design is one of the most important parts of developing applications. Nowadays, a quality user interface must not only accommodate interaction between machines and users, but also needs to recognize the differences and provide functionalities for users from role-to-role or even individual-to-individual. With the web-based application of our Teledermatology consult system, the development environment provides us highly useful opportunities to create dynamic user interfaces, which lets us to gain greater access control and has the potential to increase efficiency of the system. We will describe the two models of user interfaces in our system: Role-based and Adaptive. PMID:14728419

  10. Plant neighbor identity influences plant biochemistry and physiology related to defense

    PubMed Central

    2010-01-01

    Background Chemical and biological processes dictate an individual organism's ability to recognize and respond to other organisms. A small but growing body of evidence suggests that plants may be capable of recognizing and responding to neighboring plants in a species specific fashion. Here we tested whether or not individuals of the invasive exotic weed, Centaurea maculosa, would modulate their defensive strategy in response to different plant neighbors. Results In the greenhouse, C. maculosa individuals were paired with either conspecific (C. maculosa) or heterospecific (Festuca idahoensis) plant neighbors and elicited with the plant defense signaling molecule methyl jasmonate to mimic insect herbivory. We found that elicited C. maculosa plants grown with conspecific neighbors exhibited increased levels of total phenolics, whereas those grown with heterospecific neighbors allocated more resources towards growth. To further investigate these results in the field, we conducted a metabolomics analysis to explore chemical differences between individuals of C. maculosa growing in naturally occurring conspecific and heterospecific field stands. Similar to the greenhouse results, C. maculosa individuals accumulated higher levels of defense-related secondary metabolites and lower levels of primary metabolites when growing in conspecific versus heterospecific field stands. Leaf herbivory was similar in both stand types; however, a separate field study positively correlated specialist herbivore load with higher densities of C. maculosa conspecifics. Conclusions Our results suggest that an individual C. maculosa plant can change its defensive strategy based on the identity of its plant neighbors. This is likely to have important consequences for individual and community success. PMID:20565801

  11. Plant neighbor identity influences plant biochemistry and physiology related to defense.

    PubMed

    Broz, Amanda K; Broeckling, Corey D; De-la-Peña, Clelia; Lewis, Matthew R; Greene, Erick; Callaway, Ragan M; Sumner, Lloyd W; Vivanco, Jorge M

    2010-06-17

    Chemical and biological processes dictate an individual organism's ability to recognize and respond to other organisms. A small but growing body of evidence suggests that plants may be capable of recognizing and responding to neighboring plants in a species specific fashion. Here we tested whether or not individuals of the invasive exotic weed, Centaurea maculosa, would modulate their defensive strategy in response to different plant neighbors. In the greenhouse, C. maculosa individuals were paired with either conspecific (C. maculosa) or heterospecific (Festuca idahoensis) plant neighbors and elicited with the plant defense signaling molecule methyl jasmonate to mimic insect herbivory. We found that elicited C. maculosa plants grown with conspecific neighbors exhibited increased levels of total phenolics, whereas those grown with heterospecific neighbors allocated more resources towards growth. To further investigate these results in the field, we conducted a metabolomics analysis to explore chemical differences between individuals of C. maculosa growing in naturally occurring conspecific and heterospecific field stands. Similar to the greenhouse results, C. maculosa individuals accumulated higher levels of defense-related secondary metabolites and lower levels of primary metabolites when growing in conspecific versus heterospecific field stands. Leaf herbivory was similar in both stand types; however, a separate field study positively correlated specialist herbivore load with higher densities of C. maculosa conspecifics. Our results suggest that an individual C. maculosa plant can change its defensive strategy based on the identity of its plant neighbors. This is likely to have important consequences for individual and community success.

  12. The Relationship between the Recognition of Facial Expressions and Self-Reported Anger in People with Intellectual Disabilities

    ERIC Educational Resources Information Center

    Woodcock, Kate A.; Rose, John

    2007-01-01

    Background: This study aims to examine the relationship between how individuals with intellectual disabilities report their own levels of anger, and the ability of those individuals to recognize emotions. It was hypothesized that increased expression of anger would be linked to lower ability to recognize facial emotional expressions and increased…

  13. Colored halos around faces and emotion-evoked colors: a new form of synesthesia.

    PubMed

    Ramachandran, Vilayanur S; Miller, Luke; Livingstone, Margaret S; Brang, David

    2012-01-01

    The claim that some individuals see colored halos or auras around faces has long been part of popular folklore. Here we report on a 23-year-old man (subject TK) diagnosed with Asperger's disorder, who began to consistently experience colors around individuals at the age of 10. TK's colors are based on the individual's identity and emotional connotation. We interpret these experiences as a form of synesthesia, and confirm their authenticity through a target detection paradigm. Additionally, we investigate TK's claim that emotions evoke highly specific colors, allowing him, despite his Asperger's, to introspect on emotions and recognize them in others.

  14. Infant perceptual development for faces and spoken words: An integrated approach

    PubMed Central

    Watson, Tamara L; Robbins, Rachel A; Best, Catherine T

    2014-01-01

    There are obvious differences between recognizing faces and recognizing spoken words or phonemes that might suggest development of each capability requires different skills. Recognizing faces and perceiving spoken language, however, are in key senses extremely similar endeavors. Both perceptual processes are based on richly variable, yet highly structured input from which the perceiver needs to extract categorically meaningful information. This similarity could be reflected in the perceptual narrowing that occurs within the first year of life in both domains. We take the position that the perceptual and neurocognitive processes by which face and speech recognition develop are based on a set of common principles. One common principle is the importance of systematic variability in the input as a source of information rather than noise. Experience of this variability leads to perceptual tuning to the critical properties that define individual faces or spoken words versus their membership in larger groupings of people and their language communities. We argue that parallels can be drawn directly between the principles responsible for the development of face and spoken language perception. PMID:25132626

  15. Global ensemble texture representations are critical to rapid scene perception.

    PubMed

    Brady, Timothy F; Shafer-Skelton, Anna; Alvarez, George A

    2017-06-01

    Traditionally, recognizing the objects within a scene has been treated as a prerequisite to recognizing the scene itself. However, research now suggests that the ability to rapidly recognize visual scenes could be supported by global properties of the scene itself rather than the objects within the scene. Here, we argue for a particular instantiation of this view: That scenes are recognized by treating them as a global texture and processing the pattern of orientations and spatial frequencies across different areas of the scene without recognizing any objects. To test this model, we asked whether there is a link between how proficient individuals are at rapid scene perception and how proficiently they represent simple spatial patterns of orientation information (global ensemble texture). We find a significant and selective correlation between these tasks, suggesting a link between scene perception and spatial ensemble tasks but not nonspatial summary statistics In a second and third experiment, we additionally show that global ensemble texture information is not only associated with scene recognition, but that preserving only global ensemble texture information from scenes is sufficient to support rapid scene perception; however, preserving the same information is not sufficient for object recognition. Thus, global ensemble texture alone is sufficient to allow activation of scene representations but not object representations. Together, these results provide evidence for a view of scene recognition based on global ensemble texture rather than a view based purely on objects or on nonspatially localized global properties. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  16. Recognizing an individual face: 3D shape contributes earlier than 2D surface reflectance information.

    PubMed

    Caharel, Stéphanie; Jiang, Fang; Blanz, Volker; Rossion, Bruno

    2009-10-01

    The human brain recognizes faces by means of two main diagnostic sources of information: three-dimensional (3D) shape and two-dimensional (2D) surface reflectance. Here we used event-related potentials (ERPs) in a face adaptation paradigm to examine the time-course of processing for these two types of information. With a 3D morphable model, we generated pairs of faces that were either identical, varied in 3D shape only, in 2D surface reflectance only, or in both. Sixteen human observers discriminated individual faces in these 4 types of pairs, in which a first (adapting) face was followed shortly by a second (test) face. Behaviorally, observers were as accurate and as fast for discriminating individual faces based on either 3D shape or 2D surface reflectance alone, but were faster when both sources of information were present. As early as the face-sensitive N170 component (approximately 160 ms following the test face), there was larger amplitude for changes in 3D shape relative to the repetition of the same face, especially over the right occipito-temporal electrodes. However, changes in 2D reflectance between the adapter and target face did not increase the N170 amplitude. At about 250 ms, both 3D shape and 2D reflectance contributed equally, and the largest difference in amplitude compared to the repetition of the same face was found when both 3D shape and 2D reflectance were combined, in line with observers' behavior. These observations indicate that evidence to recognize individual faces accumulate faster in the right hemisphere human visual cortex from diagnostic 3D shape information than from 2D surface reflectance information.

  17. Exploring Perceived Discrimination Among LGBT Individuals in Turkey in Education, Employment, and Health Care: Results of an Online Survey.

    PubMed

    Göçmen, İpek; Yılmaz, Volkan

    2017-01-01

    This article explores the discrimination practices encountered by lesbian, gay, bisexual, and transgender (LGBT) individuals in education, income, employment, and health care in Turkey. Limited quantitative data on LGBT individuals are available in Turkey. This study collected data from 2,875 LGBT individuals through a Web-based survey. The findings suggest that LGBT individuals report perceived direct and indirect discrimination in accessing education, employment, and health care. In a country where LGBT rights are not yet recognized and antidiscrimination legislation covering sexual orientation and gender identity is still nonexistent, findings demonstrate perceived discrimination of LGBTs rarely turns into a legal complaint. Even when they do, most LGBTs in our sample report that they did not feel that the justice system addressed their grievances.

  18. Agreement Between Bard College and the Bard College Chapter of the American Association of University Professors. 1978-1979.

    ERIC Educational Resources Information Center

    Bard Coll., Annandale-on-Hudson, NY.

    An agreement between Bard College and Bard College Chapter of the AAUP is presented. The college recognized the Chapter as a collective bargaining agent for the faculty but also recognizes the right of individual faculty members or the college president to discuss and establish particular arrangements to cover individual faculty employment…

  19. Subject-independent emotion recognition based on physiological signals: a three-stage decision method.

    PubMed

    Chen, Jing; Hu, Bin; Wang, Yue; Moore, Philip; Dai, Yongqiang; Feng, Lei; Ding, Zhijie

    2017-12-20

    Collaboration between humans and computers has become pervasive and ubiquitous, however current computer systems are limited in that they fail to address the emotional component. An accurate understanding of human emotions is necessary for these computers to trigger proper feedback. Among multiple emotional channels, physiological signals are synchronous with emotional responses; therefore, analyzing physiological changes is a recognized way to estimate human emotions. In this paper, a three-stage decision method is proposed to recognize four emotions based on physiological signals in the multi-subject context. Emotion detection is achieved by using a stage-divided strategy in which each stage deals with a fine-grained goal. The decision method consists of three stages. During the training process, the initial stage transforms mixed training subjects to separate groups, thus eliminating the effect of individual differences. The second stage categorizes four emotions into two emotion pools in order to reduce recognition complexity. The third stage trains a classifier based on emotions in each emotion pool. During the testing process, a test case or test trial will be initially classified to a group followed by classification into an emotion pool in the second stage. An emotion will be assigned to the test trial in the final stage. In this paper we consider two different ways of allocating four emotions into two emotion pools. A comparative analysis is also carried out between the proposal and other methods. An average recognition accuracy of 77.57% was achieved on the recognition of four emotions with the best accuracy of 86.67% to recognize the positive and excited emotion. Using differing ways of allocating four emotions into two emotion pools, we found there is a difference in the effectiveness of a classifier on learning each emotion. When compared to other methods, the proposed method demonstrates a significant improvement in recognizing four emotions in the multi-subject context. The proposed three-stage decision method solves a crucial issue which is 'individual differences' in multi-subject emotion recognition and overcomes the suboptimal performance with respect to direct classification of multiple emotions. Our study supports the observation that the proposed method represents a promising methodology for recognizing multiple emotions in the multi-subject context.

  20. The Effects of Self-Explanation and Metacognitive Instruction on Undergraduate Students' Learning of Statistics Materials Containing Multiple External Representations in a Web-Based Environment

    ERIC Educational Resources Information Center

    Hsu, Yu-Chang

    2009-01-01

    Students in the Science, Technology, Engineering, and Mathematics (STEM) fields are confronted with multiple external representations (MERs) in their learning materials. The ability to learn from and communicate with these MERs requires not only that students comprehend each representation individually but also that students recognize how the…

  1. Addressing Social Anxiety Concurrently With Prison-Based Sex Offender Treatment: A Case of Individual Needs in an Era of Manualized Treatment.

    PubMed

    Lasher, Michael P; Webb, Jon R; Stinson, Jill D; Cantrell, Peggy J

    2017-07-01

    Emotional regulation may be an underaddressed therapeutic target in sex offender treatment. This article presents a case report of "Adam," a Caucasian male referred to a prison-based sex offender treatment program. Adam's social anxiety was recognized as an antecendent to his sexual offending, and treatment of such, as a critical adjunct to sex offender treatment, is discussed herein. Adam's individualized treatment included aspects of rational emotive behavior therapy and time-limited dynamic psychotherapy. Adam showed an increased understanding of his anxiety and improvement in his social interactions, both in the context of treatment groups and with female staff, and was willing to continue follow-up care in the community. This case provides support for the individualized treatment of incarcerated offenders as opposed to exclusively utilizing manualized psychoeducational interventions.

  2. Prevalence of sensitization to Cannabis sativa. Lipid-transfer and thaumatin-like proteins are relevant allergens.

    PubMed

    Larramendi, Carlos H; López-Matas, M Ángeles; Ferrer, Angel; Huertas, Angel Julio; Pagán, Juan Antonio; Navarro, Luis Ángel; García-Abujeta, José Luis; Andreu, Carmen; Carnés, Jerónimo

    2013-01-01

    Although allergy to Cannabis sativa was first reported over 40 years ago, the allergenicity has scarcely been studied. The objectives of this study were to investigate the frequency of sensitization to this plant, to analyze the clinical characteristics and allergenic profile of sensitized individuals and to identify the allergens involved. Five hundred and forty-five individuals in Spain attending allergy clinics with respiratory or cutaneous symptoms underwent a skin-prick test (SPT) with C. sativa leaf extract. The extract was characterized by SDS-PAGE and 2-dimensional electrophoresis. Specific IgE to C. sativa was measured in positive SPT individuals. The clinical and allergenic profiles of sensitized individuals were investigated and the most-recognized allergens sequenced and characterized by liquid chromatography-mass spectrometry/mass spectrometry. Of this preselected population, 44 individuals had positive SPT to C. sativa (prevalence 8.1%). Prevalence was higher in individuals who were C. sativa smokers (14.6%). Two individuals reported mild symptoms with C. sativa. Twenty-one individuals from 32 available sera (65.6%) had positive specific IgE to C. sativa. Twelve sera recognized at least 6 different bands in a molecular-weight range of between 10 and 60 kDa. Six of them recognized a 10-kDa band, identified as a lipid transfer protein (LTP) and 8 recognized a 38-kDa band, identified as a thaumatin-like protein. There is a high prevalence of sensitization to C. sativa leaves. The clinical symptoms directly attributed to C. sativa were uncommon and mild. The sensitization profile observed suggests that C. sativa sensitization may be mediated by two mechanisms, i.e. cross-reactivity, mainly with LTP and thaumatin-like protein, and exposure-related 'de novo' sensitization. Copyright © 2013 S. Karger AG, Basel.

  3. Three human chromosomal autoantigens are recognized by sera from patients with anti-centromere antibodies.

    PubMed Central

    Earnshaw, W; Bordwell, B; Marino, C; Rothfield, N

    1986-01-01

    We have identified 39 individuals with anti-centromere antibodies (ACA) in our patient population, all of whom have Raynaud's syndrome or disease. We have used sera from the ACA-positive patients and from 123 controls (22 normal individuals and 101 additional patients with either Raynaud's disease or Raynaud's syndrome plus an associated connective tissue disease) to screen the proteins of highly purified human (HeLa) mitotic chromosomes by sodium dodecyl sulfate polyacrylamide gel electrophoresis and immunoblotting. Three antigens were recognized by the sera from the ACA-positive patients. These were centromere protein (CENP)-B (80,000 mol wt--recognized by all ACA-positive sera), CENP-A (17,000 mol wt--recognized by 38 of 39 ACA-positive sera), and CENP-C (140,000 mol wt--recognized by 37 of 39 ACA-positive sera). None of these antigens were recognized by any of the 123 control sera, although binding was occasionally seen to other chromosomal antigens. Therefore the ACA response is highly uniform in our patient population. Antibody to CENP-B shows a 100% correlation with anti-centromere staining by indirect immunofluorescence. Images PMID:3511098

  4. Three human chromosomal autoantigens are recognized by sera from patients with anti-centromere antibodies.

    PubMed

    Earnshaw, W; Bordwell, B; Marino, C; Rothfield, N

    1986-02-01

    We have identified 39 individuals with anti-centromere antibodies (ACA) in our patient population, all of whom have Raynaud's syndrome or disease. We have used sera from the ACA-positive patients and from 123 controls (22 normal individuals and 101 additional patients with either Raynaud's disease or Raynaud's syndrome plus an associated connective tissue disease) to screen the proteins of highly purified human (HeLa) mitotic chromosomes by sodium dodecyl sulfate polyacrylamide gel electrophoresis and immunoblotting. Three antigens were recognized by the sera from the ACA-positive patients. These were centromere protein (CENP)-B (80,000 mol wt--recognized by all ACA-positive sera), CENP-A (17,000 mol wt--recognized by 38 of 39 ACA-positive sera), and CENP-C (140,000 mol wt--recognized by 37 of 39 ACA-positive sera). None of these antigens were recognized by any of the 123 control sera, although binding was occasionally seen to other chromosomal antigens. Therefore the ACA response is highly uniform in our patient population. Antibody to CENP-B shows a 100% correlation with anti-centromere staining by indirect immunofluorescence.

  5. Reframing and addressing horizontal violence as a workplace quality improvement concern.

    PubMed

    Taylor, Rosemary A; Taylor, Steven S

    2018-06-27

    To reframe horizontal violence as a quality improvement concern. Although the number of studies exploring horizontal violence has increased, evidence supporting the effectiveness of current interventions is weak and the problem persists. Often framed as an individual or interpersonal issue, horizontal violence has been recognized as a complex phenomenon that can only be understood through an examination of social, individual and organizational factors. As such, interventions to address horizontal violence must be applied systemically and address contributions from all sources. This is a discussion paper. This discussion is based on results of a study of nurses' perceptions of horizontal violence and review of the literature. Context is recognized as a contributing factor in human behavior, yet often overlooked in interventions to address horizontal violence. Moving the focus away from the individual and investigating systems contributions to horizontal violence using existing quality improvement frameworks is suggested. To date, efforts to address horizontal violence have not been proven effective. There is a call for a wider application and investigation of interventions. This reframing provides the system level application suggested and would address a broader range of factors contributing to the perpetuation of the phenomenon. © 2018 Wiley Periodicals, Inc.

  6. Habitat-dependent olfactory discrimination in three-spined sticklebacks (Gasterosteus aculeatus).

    PubMed

    Hiermes, Meike; Mehlis, Marion; Rick, Ingolf P; Bakker, Theo C M

    2015-07-01

    The ability to recognize conspecifics is indispensible for differential treatment of particular individuals in social contexts like grouping behavior. The advantages of grouping are multifarious, and there exist numerous additional benefits of joining aggregations of conspecifics. Recognition is based on different signals and transmitted via multiple channels, among others the olfactory channel. The sensory system or the combination of sensory modalities used in recognition processes is highly dependent on the availability and effectiveness of modalities, which are a function of the environmental conditions. Using F1-generations of six three-spined stickleback (Gasterosteus aculeatus) populations from two habitat types (tea-stained and clear-water lakes) from the Outer Hebrides, Scotland, we investigated whether individuals are able to recognize members of their own population solely based on olfactory cues and whether the habitat type an individual originated from had an influence on its recognition abilities. When given the choice (own vs. foreign population) sticklebacks from tea-stained lakes significantly preferred the odor of their own population, whereas fish from clear-water habitats did not show any preference. Moreover, fish from the two habitat types differed significantly in their recognition abilities, indicating that olfactory communication is better developed when visual signaling is disturbed. Thus, the observed odor preferences appear to be the consequence of different selective constraints and adaptations as a result of the differences in environmental conditions that have acted on the parental generations. These adaptations are likely genetically based as the differences are present in the F1-generation that had been reared under identical laboratory conditions.

  7. Domestic Violence and Social Justice: A Structural Intersectional Framework for Teaching About Domestic Violence.

    PubMed

    Coker, Donna

    2016-10-01

    My Domestic Violence and Social Justice law school course is organized around a structural intersectional framework to encourage students to recognize how structural inequalities inform the types of abuse perpetrated, individual and community responses to abuse, meanings that a victim ascribes to abuse, and factors that increase the risk of abuse. The course challenges the dominant neoliberal ideology focus on individual responsibility that eclipses shared responsibility. The course combines experiential exercises, a presentation by members of a community-based survivor organization, discussion of a hypothetical case with a legal practitioner, and court observation to help students apply theoretical insights to practical issues of individual representation and policy-making. © The Author(s) 2016.

  8. Processing Information about Support Exchanges in Close Relationships: The Role of a Knowledge Structure.

    PubMed

    Turan, Bulent

    2016-01-01

    People develop knowledge of interpersonal interaction patterns (e.g., prototypes and schemas), which shape how they process incoming information. One such knowledge structure based on attachment theory was examined: the secure base script (the prototypic sequence of events when an attachment figure comforts a close relationship partner in distress). In two studies (N = 53 and N = 119), participants were shown animated film clips in which geometric figures depicted the secure base script and asked to describe the animations. Both studies found that many people readily recognize the secure-base script from these minimal cues quite well, suggesting that this script is not only available in the context of specific relationships (i.e., a relationship-specific knowledge): The generalized (abstract) structure of the script is also readily accessible, which would make it possible to apply it to any relationship (including new relationships). Regression analyses suggested that participants who recognized the script were more likely to (a) include more animation elements when describing the animations, (b) see a common theme in different animations, (c) create better organized stories, and (d) later recall more details of the animations. These findings suggest that access to this knowledge structure helps a person organize and remember relevant incoming information. Furthermore, in both Study 1 and Study 2, individual differences in the ready recognition of the script were associated with individual differences in having access to another related knowledge: indicators suggesting that a potential relationship partner can be trusted to be supportive and responsive at times of stress. Results of Study 2 also suggest that recognizing the script is associated with those items of an attachment measure that concern giving and receiving support. Thus, these knowledge structures may shape how people process support-relevant information in their everyday lives, potentially affecting relationship outcomes and mental and physical health.

  9. Processing Information about Support Exchanges in Close Relationships: The Role of a Knowledge Structure

    PubMed Central

    Turan, Bulent

    2016-01-01

    People develop knowledge of interpersonal interaction patterns (e.g., prototypes and schemas), which shape how they process incoming information. One such knowledge structure based on attachment theory was examined: the secure base script (the prototypic sequence of events when an attachment figure comforts a close relationship partner in distress). In two studies (N = 53 and N = 119), participants were shown animated film clips in which geometric figures depicted the secure base script and asked to describe the animations. Both studies found that many people readily recognize the secure-base script from these minimal cues quite well, suggesting that this script is not only available in the context of specific relationships (i.e., a relationship-specific knowledge): The generalized (abstract) structure of the script is also readily accessible, which would make it possible to apply it to any relationship (including new relationships). Regression analyses suggested that participants who recognized the script were more likely to (a) include more animation elements when describing the animations, (b) see a common theme in different animations, (c) create better organized stories, and (d) later recall more details of the animations. These findings suggest that access to this knowledge structure helps a person organize and remember relevant incoming information. Furthermore, in both Study 1 and Study 2, individual differences in the ready recognition of the script were associated with individual differences in having access to another related knowledge: indicators suggesting that a potential relationship partner can be trusted to be supportive and responsive at times of stress. Results of Study 2 also suggest that recognizing the script is associated with those items of an attachment measure that concern giving and receiving support. Thus, these knowledge structures may shape how people process support-relevant information in their everyday lives, potentially affecting relationship outcomes and mental and physical health. PMID:26973562

  10. End-to-end system of license plate localization and recognition

    NASA Astrophysics Data System (ADS)

    Zhu, Siyu; Dianat, Sohail; Mestha, Lalit K.

    2015-03-01

    An end-to-end license plate recognition system is proposed. It is composed of preprocessing, detection, segmentation, and character recognition to find and recognize plates from camera-based still images. The system utilizes connected component (CC) properties to quickly extract the license plate region. A two-stage CC filtering is utilized to address both shape and spatial relationship information to produce high precision and to recall values for detection. Floating peak and valleys of projection profiles are used to cut the license plates into individual characters. A turning function-based method is proposed to quickly and accurately recognize each character. It is further accelerated using curvature histogram-based support vector machine. The INFTY dataset is used to train the recognition system, and MediaLab license plate dataset is used for testing. The proposed system achieved 89.45% F-measure for detection and 87.33% accuracy for overall recognition rate which is comparable to current state-of-the-art systems.

  11. Analysis and advocacy in home- and community-based care: an approach in three parts.

    PubMed

    Hudson, Robert B

    2010-01-01

    A new chapter in health policy presents both challenges and opportunities for aging policy analysts and advocates concerned with long-term care. Millions of long-term care recipients and providers live today in a pubic policy netherworld, one principally associated with Medicaid. I suggest here that moving policy forward will entail three key steps: (a) to overcome structural lag in key home and community-based care (HCBC) policy arenas; (b) to reverse a contemporary pattern of risk-shifting from institutions to individuals; and (c) to inform and empower caregivers to have their own pressing needs recognized. Recent developments in Washington provide new optimism on these fronts. Voluntary long-term care and community-based care (LTC/HCBC) proposals are on the table within the broad context of health care reform. Whether they remain will be, in large, part a function of how far we have moved along the fronts described: modernizing policies, recognizing risks, and activating neglected policy constituencies.

  12. A resolution recognizing February 19, 2013 as the centennial of Mosaic, a faith-based organization that was founded in Nebraska and now serves more than 3,600 individuals with intellectual disabilities in 10 States.

    THOMAS, 113th Congress

    Sen. Johanns, Mike [R-NE

    2013-02-14

    Senate - 02/14/2013 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Agreed to in SenateHere are the steps for Status of Legislation:

  13. The Gluten-Free Frenzy: Fad or Fitting?

    PubMed

    Johanson, Linda

    2015-01-01

    Although the gluten-free diet has been recognized as therapeutic for individuals suffering from celiac disease, it has been promoted recently for other indications, such as autism, chronic fatigue syn- drome, and irritable bowel syndrome, or simply as a healthy dietary choice for anyone. The basics of the gluten-free diet are explored, with evidence-based indications and nursing implications when patients choose gluten-free.

  14. Path to Personalized Medicine for Type 2 Diabetes Mellitus: Reality and Hope.

    PubMed

    Aghaei Meybodi, Hamid Reza; Hasanzad, Mandana; Larijani, Bagher

    2017-03-01

    Type 2 diabetes mellitus (T2DM) is recognized as a public health problem and increasingly prevalent illness. Key elements of the guideline for diabetes care are based on evidence-based medicine approach and apply for population, not individuals. However, individualized care can improve diabetes management. Personalized medicine is otherwise called precision medicine tries to find better prediction, prevention, and intervention for T2DM individuals. Precision medicine in diabetes refers to the utility of genomics data of a patient with diabetes to provide the most effective diagnosis strategies and treatment plans. Over 100 genetic loci influence susceptibility to T2DM. Genomics data together with the potential of other "Omics" and clinical evidence-based data will lead to diabetes care improvement in the context of personalized medicine in the near future. Breakthrough of technologies enables much greater improvements in the understanding of individual variations that may alter the T2DM outcome. This article represents a comprehensive review of current knowledge on the impact of personalized medicine in T2DM.

  15. [Biological and neural bases of partner preferences in rodents: models to understand human pair bonds].

    PubMed

    Coria-Avila, G A; Hernández-Aguilar, M E; Toledo-Cárdenas, R; García-Hernández, L I; Manzo, J; Pacheco, P; Miquel, M; Pfaus, J G

    To analyse the biological and neural bases of partner preference formation in rodents as models to understand human pair bonding. Rodents are social individuals, capable of forming short- or long-lasting partner preferences that develop slowly by stimuli like cohabitation, or rapidly by stimuli like sex and stress. Dopamine, corticosteroids, oxytocin, vasopressin, and opioids form the neurochemical substrate for pair bonding in areas like the nucleus accumbens, the prefrontal cortex, the piriform cortex, the medial preoptic area, the ventral tegmental area and the medial amygdala, among others. Additional areas may participate depending on the nature of the conditioned stimuli by which and individual recognizes a preferred partner. Animal models help us understand that the capacity of an individual to display long-lasting and selective preferences depends on neural bases, selected throughout evolution. The challenge in neuroscience is to use this knowledge to create new solutions for mental problems associated with the incapacity of an individual to display a social bond, keep one, or cope with the disruption of a consolidated one.

  16. A voxel-based lesion study on facial emotion recognition after penetrating brain injury

    PubMed Central

    Dal Monte, Olga; Solomon, Jeffrey M.; Schintu, Selene; Knutson, Kristine M.; Strenziok, Maren; Pardini, Matteo; Leopold, Anne; Raymont, Vanessa; Grafman, Jordan

    2013-01-01

    The ability to read emotions in the face of another person is an important social skill that can be impaired in subjects with traumatic brain injury (TBI). To determine the brain regions that modulate facial emotion recognition, we conducted a whole-brain analysis using a well-validated facial emotion recognition task and voxel-based lesion symptom mapping (VLSM) in a large sample of patients with focal penetrating TBIs (pTBIs). Our results revealed that individuals with pTBI performed significantly worse than normal controls in recognizing unpleasant emotions. VLSM mapping results showed that impairment in facial emotion recognition was due to damage in a bilateral fronto-temporo-limbic network, including medial prefrontal cortex (PFC), anterior cingulate cortex, left insula and temporal areas. Beside those common areas, damage to the bilateral and anterior regions of PFC led to impairment in recognizing unpleasant emotions, whereas bilateral posterior PFC and left temporal areas led to impairment in recognizing pleasant emotions. Our findings add empirical evidence that the ability to read pleasant and unpleasant emotions in other people's faces is a complex process involving not only a common network that includes bilateral fronto-temporo-limbic lobes, but also other regions depending on emotional valence. PMID:22496440

  17. Experience with Malleable Objects Influences Shape-based Object Individuation by Infants

    PubMed Central

    Woods, Rebecca J.; Schuler, Jena

    2014-01-01

    Infants’ ability to accurately represent and later recognize previously viewed objects, and conversely, to discriminate novel objects from those previously seen improves remarkably over the first two years of life. During this time, infants acquire extensive experience viewing and manipulating objects and these experiences influence their physical reasoning. Here we posited that infants’ observations of object feature stability (rigid versus malleable) can influence use of those features to individuate two successively viewed objects. We showed 8.5-month-olds a series of objects that could or could not change shape then assessed their use of shape as a basis for object individuation. Infants who explored rigid objects later used shape differences to individuate objects; however, infants who explored malleable objects did not. This outcome suggests that the latter infants did not take into account shape differences during the physical reasoning task and provides further evidence that infants’ attention to object features can be readily modified based on recent experiences. PMID:24561541

  18. Evaluation models of some morphological characteristics for talent scouting in sport.

    PubMed

    Rogulj, Nenad; Papić, Vladan; Cavala, Marijana

    2009-03-01

    In this paper, for the purpose of expert system evaluation within the scientific project "Talent scouting in sport", two methodological approaches for recognizing an athlete's morphological compatibility for various sports has been presented, evaluated and compared. First approach is based on the fuzzy logic and expert opinion about compatibility of proposed hypothetical morphological models for 14 different sports which are part of the expert system. Second approach is based on determining the differences between morphological characteristics of a tested individual and top athlete's morphological characteristics for particular sport. Logical and mathematical bases of both methodological approaches have been explained in detail. High prognostic efficiency in recognition of individual's sport has been determined. Some improvements in further development of both methods have been proposed. Results of the research so far suggest that this or similar approaches can be successfully used for detection of individual's morphological compatibility for different sports. Also, it is expected to be useful in the selection of young talents for particular sport.

  19. A review of interprofessional dissemination and education interventions for recognizing and managing dementia

    PubMed Central

    Galvin, James E.

    2014-01-01

    The number of individuals with dementia is expected to increase dramatically over the next 20 years. Given the complicated clinical, sociobehavioral, and caregiving skills that are needed to comprehensively assess and manage individuals with dementia, the gold standard of care requires involvement of an interprofessional team. This systematic review examined 4,023 abstracts, finding 18 papers from 16 studies where an interprofessional dissemination program was performed. Most studies found some improvement in clinician knowledge or confidence, or patient outcomes, though methods and patient and clinician populations were disparate. While a significant evidence base for assessing and managing individuals with dementia has been developed, few studies have examined how to disseminate this research, and even fewer in an interprofessional manner. These findings suggest that greater emphasis needs to be placed on disseminating existing evidence-based care and ensuring that programs are interprofessional in nature so that excellent, patient-centered care is provided. PMID:23879387

  20. Towards automated assistance for operating home medical devices.

    PubMed

    Gao, Zan; Detyniecki, Marcin; Chen, Ming-Yu; Wu, Wen; Hauptmann, Alexander G; Wactlar, Howard D

    2010-01-01

    To detect errors when subjects operate a home medical device, we observe them with multiple cameras. We then perform action recognition with a robust approach to recognize action information based on explicitly encoding motion information. This algorithm detects interest points and encodes not only their local appearance but also explicitly models local motion. Our goal is to recognize individual human actions in the operations of a home medical device to see if the patient has correctly performed the required actions in the prescribed sequence. Using a specific infusion pump as a test case, requiring 22 operation steps from 6 action classes, our best classifier selects high likelihood action estimates from 4 available cameras, to obtain an average class recognition rate of 69%.

  1. Problem severity and motivation for treatment in incarcerated substance abusers.

    PubMed

    Hiller, Matthew L; Narevic, Egle; Webster, J Matthew; Rosen, Paul; Staton, Michele; Leukefeld, Carl; Garrity, Thomas F; Kayo, Rebecca

    2009-01-01

    Studies of community-based treatment programs for substance users document that motivation for treatment is a consistent predictor of clients remaining under treatment for a longer period of time. Recent research has replicated this in prison-based treatment programs, implying that motivation is clinically important regardless of setting. The current study examines predictors of treatment motivation using data collected from 661 male drug-involved inmates during in-depth interviews that include components of the Addiction Severity Index, TCU Motivation Scale, and the Heath Services Research Instrument. Findings showed treatment motivation can be measured effectively in prison-based settings. Motivation scores were not significantly different between individuals in a prison-based treatment program and those in the general prison population. Furthermore, higher motivation for treatment scores were associated with greater levels of problem severity, suggesting that individuals with more drug-use related life problems may recognize this need and desire help for beginning long-term recovery.

  2. Discovering Activities to Recognize and Track in a Smart Environment.

    PubMed

    Rashidi, Parisa; Cook, Diane J; Holder, Lawrence B; Schmitter-Edgecombe, Maureen

    2011-01-01

    The machine learning and pervasive sensing technologies found in smart homes offer unprecedented opportunities for providing health monitoring and assistance to individuals experiencing difficulties living independently at home. In order to monitor the functional health of smart home residents, we need to design technologies that recognize and track activities that people normally perform as part of their daily routines. Although approaches do exist for recognizing activities, the approaches are applied to activities that have been pre-selected and for which labeled training data is available. In contrast, we introduce an automated approach to activity tracking that identifies frequent activities that naturally occur in an individual's routine. With this capability we can then track the occurrence of regular activities to monitor functional health and to detect changes in an individual's patterns and lifestyle. In this paper we describe our activity mining and tracking approach and validate our algorithms on data collected in physical smart environments.

  3. Overview on Sobemoviruses and a Proposal for the Creation of the Family Sobemoviridae

    PubMed Central

    Sõmera, Merike; Sarmiento, Cecilia; Truve, Erkki

    2015-01-01

    The genus Sobemovirus, unassigned to any family, consists of viruses with single-stranded plus-oriented single-component RNA genomes and small icosahedral particles. Currently, 14 species within the genus have been recognized by the International Committee on Taxonomy of Viruses (ICTV) but several new species are to be recognized in the near future. Sobemovirus genomes are compact with a conserved structure of open reading frames and with short untranslated regions. Several sobemoviruses are important pathogens. Moreover, over the last decade sobemoviruses have become important model systems to study plant virus evolution. In the current review we give an overview of the structure and expression of sobemovirus genomes, processing and functions of individual proteins, particle structure, pathology and phylogenesis of sobemoviruses as well as of satellite RNAs present together with these viruses. Based on a phylogenetic analysis we propose that a new family Sobemoviridae should be recognized including the genera Sobemovirus and Polemovirus. Finally, we outline the future perspectives and needs for the research focusing on sobemoviruses. PMID:26083319

  4. Recognition of central sensitization in patients with musculoskeletal pain: Application of pain neurophysiology in manual therapy practice.

    PubMed

    Nijs, Jo; Van Houdenhove, Boudewijn; Oostendorp, Rob A B

    2010-04-01

    Central sensitization plays an important role in the pathophysiology of numerous musculoskeletal pain disorders, yet it remains unclear how manual therapists can recognize this condition. Therefore, mechanism based clinical guidelines for the recognition of central sensitization in patients with musculoskeletal pain are provided. By using our current understanding of central sensitization during the clinical assessment of patients with musculoskeletal pain, manual therapists can apply the science of nociceptive and pain processing neurophysiology to the practice of manual therapy. The diagnosis/assessment of central sensitization in individual patients with musculoskeletal pain is not straightforward, however manual therapists can use information obtained from the medical diagnosis, combined with the medical history of the patient, as well as the clinical examination and the analysis of the treatment response in order to recognize central sensitization. The clinical examination used to recognize central sensitization entails the distinction between primary and secondary hyperalgesia. Copyright 2009 Elsevier Ltd. All rights reserved.

  5. 78 FR 13236 - TRICARE: Smoking Cessation Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-27

    ... National Community Pharmacists Association felt that since some retail pharmacists provide smoking... and Medicaid Services (CMS), pharmacists are not recognized as authorized TRICARE independent... individual pharmacist is not recognized as an independent provider. Therefore, pharmacist counseling services...

  6. Electrostatic Charging of Lunar Dust by UV Photoelectric Emissions and Solar Wind Electrons

    NASA Technical Reports Server (NTRS)

    Abbas, Mian M.; Tankosic, Dragana; Spann, James f.; LeClair, Andre C.; Dube, Michael J.

    2008-01-01

    The ubiquitous presence of dust in the lunar environment with its high adhesive characteristics has been recognized to be a major safety issue that must be addressed in view of its hazardous effects on robotic and human exploration of the Moon. The reported observations of a horizon glow and streamers at the lunar terminator during the Apollo missions are attributed to the sunlight scattered by the levitated lunar dust. The lunar surface and the dust grains are predominantly charged positively by the incident UV solar radiation on the dayside and negatively by the solar wind electrons on the night-side. The charged dust grains are levitated and transported over long distances by the established electric fields. A quantitative understanding of the lunar dust phenomena requires development of global dust distribution models, based on an accurate knowledge of lunar dust charging properties. Currently available data of lunar dust charging is based on bulk materials, although it is well recognized that measurements on individual dust grains are expected to be substantially different from the bulk measurements. In this paper we present laboratory measurements of charging properties of Apollo 11 & 17 dust grains by UV photoelectric emissions and by electron impact. These measurements indicate substantial differences of both qualitative and quantitative nature between dust charging properties of individual micron/submicron sized dust grains and of bulk materials. In addition, there are no viable theoretical models available as yet for calculation of dust charging properties of individual dust grains for both photoelectric emissions and electron impact. It is thus of paramount importance to conduct comprehensive measurements for charging properties of individual dust grains in order to develop realistic models of dust processes in the lunar atmosphere, and address the hazardous issues of dust on lunar robotic and human missions.

  7. Gender-based prototype formation in face recognition.

    PubMed

    Baudouin, Jean-Yves; Brochard, Renaud

    2011-07-01

    The role of gender categories in prototype formation during face recognition was investigated in 2 experiments. The participants were asked to learn individual faces and then to recognize them. During recognition, individual faces were mixed with faces, which were blended faces of same or different genders. The results of the 2 experiments showed that blended faces made with learned individual faces were recognized, even though they had never been seen before. In Experiment 1, this effect was stronger when faces belonged to the same gender category (same-sex blended faces), but it also emerged across gender categories (cross-sex blended faces). Experiment 2 further showed that this prototype effect was not affected by the presentation order for same-sex blended faces: The effect was equally strong when the faces were presented one after the other during learning or alternated with faces of the opposite gender. By contrast, the prototype effect across gender categories was highly sensitive to the temporal proximity of the faces blended into the blended faces and almost disappeared when other faces were intermixed. These results indicate that distinct neural populations code for female and male faces. However, the formation of a facial representation can also be mediated by both neural populations. The implications for face-space properties and face-encoding processes are discussed.

  8. Are Africans, Europeans, and Asians Different "Races"? A Guided-Inquiry Lab for Introducing Undergraduate Students to Genetic Diversity and Preparing Them to Study Natural Selection

    ERIC Educational Resources Information Center

    Kalinowski, Steven T.; Andrews, Tessa M.; Leonard, Mary J.; Snodgrass, Meagan

    2012-01-01

    Many students do not recognize that individual organisms within populations vary, and this may make it difficult for them to recognize the essential role variation plays in natural selection. Also, many students have weak scientific reasoning skills, and this makes it difficult for them to recognize misconceptions they might have. This paper…

  9. 42 CFR 24.6 - Pay and compensation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... members: (1) Impact of the individual on the scientific field; (2) Recognition of the individual by the scientific community; (3) Originality of the individual's ideas/work products; (4) Specific “clinical” or... recognize individual scientific value and as necessary to recruit or retain an exceptionally well-qualified...

  10. A biologically plausible computational model for auditory object recognition.

    PubMed

    Larson, Eric; Billimoria, Cyrus P; Sen, Kamal

    2009-01-01

    Object recognition is a task of fundamental importance for sensory systems. Although this problem has been intensively investigated in the visual system, relatively little is known about the recognition of complex auditory objects. Recent work has shown that spike trains from individual sensory neurons can be used to discriminate between and recognize stimuli. Multiple groups have developed spike similarity or dissimilarity metrics to quantify the differences between spike trains. Using a nearest-neighbor approach the spike similarity metrics can be used to classify the stimuli into groups used to evoke the spike trains. The nearest prototype spike train to the tested spike train can then be used to identify the stimulus. However, how biological circuits might perform such computations remains unclear. Elucidating this question would facilitate the experimental search for such circuits in biological systems, as well as the design of artificial circuits that can perform such computations. Here we present a biologically plausible model for discrimination inspired by a spike distance metric using a network of integrate-and-fire model neurons coupled to a decision network. We then apply this model to the birdsong system in the context of song discrimination and recognition. We show that the model circuit is effective at recognizing individual songs, based on experimental input data from field L, the avian primary auditory cortex analog. We also compare the performance and robustness of this model to two alternative models of song discrimination: a model based on coincidence detection and a model based on firing rate.

  11. Dose limits for astronauts

    NASA Technical Reports Server (NTRS)

    Sinclair, W. K.

    2000-01-01

    Radiation exposures to individuals in space can greatly exceed natural radiation exposure on Earth and possibly normal occupational radiation exposures as well. Consequently, procedures limiting exposures would be necessary. Limitations were proposed by the Radiobiological Advisory Panel of the National Academy of Sciences/National Research Council in 1970. This panel recommended short-term limits to avoid deterministic effects and a single career limit (of 4 Sv) based on a doubling of the cancer risk in men aged 35 to 55. Later, when risk estimates for cancer had increased and were recognized to be age and sex dependent, the NCRP, in Report No. 98 in 1989, recommended a range of career limits based on age and sex from 1 to 4 Sv. NCRP is again in the process of revising recommendations for astronaut exposure, partly because risk estimates have increased further and partly to recognize trends in limiting radiation exposure occupationally on the ground. The result of these considerations is likely to be similar short-term limits for deterministic effects but modified career limits.

  12. Moderate Effects of Same-Sex Legislation on Dependent Employer-Based Insurance Coverage among Sexual Minorities

    PubMed Central

    Tran, Linda Diem

    2016-01-01

    A difference-in-difference approach was used to compare the effects of same-sex domestic partnership, civil union, and marriage policies on same- and different-sex partners who could have benefitted from their partners’ employer-based insurance (EBI) coverage. Same-sex partners had 78% lower odds (ME=-21%) of having EBI compared to different-sex partners, adjusting for socioeconomic and health-related factors. Same-sex partners living in states that recognized same-sex marriage or domestic partnership had 89% greater odds of having EBI compared to those in states that did not recognize same-sex unions (ME=5%). The impact of same-sex legislation on increasing take-up of dependent EBI coverage among lesbians, gay men, and bisexual individuals (LGBs) was modest, and domestic partnership legislation was equally as effective as same-sex marriage in increasing same-sex partner EBI coverage. Extending dependent EBI coverage to same-sex partners can mitigate gaps in coverage for a segment of the LGB population but will not eliminate them. PMID:26762647

  13. Is Emotion Recognition Impaired in Individuals with Autism Spectrum Disorders?

    ERIC Educational Resources Information Center

    Tracy, Jessica L.; Robins, Richard W.; Schriber, Roberta A.; Solomon, Marjorie

    2011-01-01

    Researchers have argued that individuals with autism spectrum disorders (ASDs) use an effortful "systematizing" process to recognize emotion expressions, whereas typically developing (TD) individuals use a more holistic process. If this is the case, individuals with ASDs should show slower and less efficient emotion recognition, particularly for…

  14. Environmental awareness -- An interactive multimedia CD-ROM

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huntelmann, A.; Petruk, M.W.

    1998-07-01

    As corporations move to new and innovative ways of structuring high-performance work teams, effective training is being recognized as a key to insuring success. Time and scheduling constraints tend to limit the effectiveness of traditional approaches to training. This has led Edmonton Power Inc. to explore the use of CD-ROM based multimedia as a means of delivering individualized instruction in an effective and timely manner. This session will demonstrate a multimedia CD-ROM based course on Environmental Awareness designed for workers in the electrical utilities industry. The objective of the course is to make workers aware of their roles and responsibilitiesmore » with respect to their impact on the environment. This session will also describe the instructional design strategy underlying this approach to training and will present some preliminary findings with respect to the effectiveness of this approach. Individuals who are interested in improving the effectiveness of their environmental training program as well as individuals who are interested in understanding the strengths of multimedia CD-ROM based training will find this session useful and informative.« less

  15. Systems and methods for biometric identification using the acoustic properties of the ear canal

    DOEpatents

    Bouchard, A.M.; Osbourn, G.C.

    1998-07-28

    The present invention teaches systems and methods for verifying or recognizing a person`s identity based on measurements of the acoustic response of the individual`s ear canal. The system comprises an acoustic emission device, which emits an acoustic source signal s(t), designated by a computer, into the ear canal of an individual, and an acoustic response detection device, which detects the acoustic response signal f(t). A computer digitizes the response (detected) signal f(t) and stores the data. Computer-implemented algorithms analyze the response signal f(t) to produce ear-canal feature data. The ear-canal feature data obtained during enrollment is stored on the computer, or some other recording medium, to compare the enrollment data with ear-canal feature data produced in a subsequent access attempt, to determine if the individual has previously been enrolled. The system can also be adapted for remote access applications. 5 figs.

  16. On the existence of a threshold for preventive behavioral responses to suppress epidemic spreading.

    PubMed

    Sahneh, Faryad Darabi; Chowdhury, Fahmida N; Scoglio, Caterina M

    2012-01-01

    The spontaneous behavioral responses of individuals to the progress of an epidemic are recognized to have a significant impact on how the infection spreads. One observation is that, even if the infection strength is larger than the classical epidemic threshold, the initially growing infection can diminish as the result of preventive behavioral patterns adopted by the individuals. In order to investigate such dynamics of the epidemic spreading, we use a simple behavioral model coupled with the individual-based SIS epidemic model where susceptible individuals adopt a preventive behavior when sensing infection. We show that, given any infection strength and contact topology, there exists a region in the behavior-related parameter space such that infection cannot survive in long run and is completely contained. Several simulation results, including a spreading scenario in a realistic contact network from a rural district in the State of Kansas, are presented to support our analytical arguments.

  17. Federally-Recognized Tribes of the Columbia-Snake Basin.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    United States. Bonneville Power Administration

    This is an omnibus publication about the federally-recognized Indian tribes of the Columbia-Snake river basin, as presented by themselves. It showcases several figurative and literal snapshots of each tribe, bits and pieces of each tribe`s story. Each individual tribe or tribal confederation either submitted its own section to this publication, or developed its own section with the assistance of the writer-editor. A federally-recognized tribe is an individual Indian group, or confederation of Indian groups, officially acknowledged by the US government for purposes of legislation, consultation and benefits. This publication is designed to be used both as a resource and asmore » an introduction to the tribes. Taken together, the sections present a rich picture of regional indian culture and history, as told by the tribes.« less

  18. Deficits in facial affect recognition among antisocial populations: a meta-analysis.

    PubMed

    Marsh, Abigail A; Blair, R J R

    2008-01-01

    Individuals with disorders marked by antisocial behavior frequently show deficits in recognizing displays of facial affect. Antisociality may be associated with specific deficits in identifying fearful expressions, which would implicate dysfunction in neural structures that subserve fearful expression processing. A meta-analysis of 20 studies was conducted to assess: (a) if antisocial populations show any consistent deficits in recognizing six emotional expressions; (b) beyond any generalized impairment, whether specific fear recognition deficits are apparent; and (c) if deficits in fear recognition are a function of task difficulty. Results show a robust link between antisocial behavior and specific deficits in recognizing fearful expressions. This impairment cannot be attributed solely to task difficulty. These results suggest dysfunction among antisocial individuals in specified neural substrates, namely the amygdala, involved in processing fearful facial affect.

  19. Disseminating treatment for anxiety disorders: step 1: recognizing the problem as a precursor to seeking help.

    PubMed

    Coles, Meredith E; Schubert, Jessica R; Heimberg, Richard G; Weiss, Barry D

    2014-12-01

    Untreated mental illness is a substantial public health issue in the United States, with only approximately 1/3 of the estimated 46 million adults in the US with mental illness receiving treatment. Many of the individuals with mental illness suffer from excessive anxiety, as over 25% of Americans experience an anxiety disorder during their lifetime and most of these individuals remain untreated. Building from the premise that recognizing one's symptoms precedes requests for help, the current paper presents data from 577 adults (50% Caucasian, 50% African American) in the US regarding their ability to recognize anxiety disorders. Findings from a national survey showed that when presented with detailed vignettes portraying symptoms and their impact, 50% of respondents correctly recognized depression, whereas less than 20% correctly recognized the anxiety disorders. Recognition that the symptoms were a cause for concern was much more common, with 75% or more of the sample noting concern. Responses were surprisingly similar across the two races, and few consistent moderators were found. In conclusion, increasing recognition of anxiety disorders may be a useful first step toward increasing service utilization. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. The causality between smoking and lung cancer among groups and individuals: addressing issues in tobacco litigation in South Korea

    PubMed Central

    Khang, Young-Ho

    2015-01-01

    This article discusses issues on the causality between smoking and lung cancer, which have been raised during the tobacco litigation in South Korea. It should be recognized that the explanatory ability of risk factor(s) for inter-individual variations in disease occurrence is different from the causal contribution of the risk factor(s) to disease occurrence. The affected subjects of the tobacco litigation in South Korea are lung cancer patients with a history of cigarette smoking. Thus, the attributable fraction of the exposed rather than the population attributable fraction should be used in the tobacco litigation regarding the causal contribution of smoking to lung cancer. Scientific evidence for the causal relationship between smoking and lung cancer is based on studies of individuals and groups, studies in animals and humans, studies that are observational or experimental, studies in laboratories and communities, and studies in both underdeveloped and developed countries. The scientific evidence collected is applicable to both groups and individuals. The probability of causation, which is calculated based on the attributable fraction for the association between smoking and lung cancer, could be utilized as evidence to prove causality in individuals. PMID:26137845

  1. The causality between smoking and lung cancer among groups and individuals: addressing issues in tobacco litigation in South Korea.

    PubMed

    Khang, Young-Ho

    2015-01-01

    This article discusses issues on the causality between smoking and lung cancer, which have been raised during the tobacco litigation in South Korea. It should be recognized that the explanatory ability of risk factor(s) for inter-individual variations in disease occurrence is different from the causal contribution of the risk factor(s) to disease occurrence. The affected subjects of the tobacco litigation in South Korea are lung cancer patients with a history of cigarette smoking. Thus, the attributable fraction of the exposed rather than the population attributable fraction should be used in the tobacco litigation regarding the causal contribution of smoking to lung cancer. Scientific evidence for the causal relationship between smoking and lung cancer is based on studies of individuals and groups, studies in animals and humans, studies that are observational or experimental, studies in laboratories and communities, and studies in both underdeveloped and developed countries. The scientific evidence collected is applicable to both groups and individuals. The probability of causation, which is calculated based on the attributable fraction for the association between smoking and lung cancer, could be utilized as evidence to prove causality in individuals.

  2. Bat wing biometrics: using collagen–elastin bundles in bat wings as a unique individual identifier

    Treesearch

    Sybill K. Amelon; Sarah E. Hooper; Kathryn M. Womack

    2017-01-01

    The ability to recognize individuals within an animal population is fundamental to conservation and management. Identification of individual bats has relied on artificial marking techniques that may negatively affect the survival and alter the behavior of individuals. Biometric systems use biological characteristics to identify individuals. The field of animal...

  3. Deficits in recognizing disgust facial expressions and Internet addiction: Perceived stress as a mediator.

    PubMed

    Chen, Zhongting; Poon, Kai-Tak; Cheng, Cecilia

    2017-08-01

    Studies have examined social maladjustment among individuals with Internet addiction, but little is known about their deficits in specific social skills and the underlying psychological mechanisms. The present study filled these gaps by (a) establishing a relationship between deficits in facial expression recognition and Internet addiction, and (b) examining the mediating role of perceived stress that explains this hypothesized relationship. Ninety-seven participants completed validated questionnaires that assessed their levels of Internet addiction and perceived stress, and performed a computer-based task that measured their facial expression recognition. The results revealed a positive relationship between deficits in recognizing disgust facial expression and Internet addiction, and this relationship was mediated by perceived stress. However, the same findings did not apply to other facial expressions. Ad hoc analyses showed that recognizing disgust was more difficult than recognizing other facial expressions, reflecting that the former task assesses a social skill that requires cognitive astuteness. The present findings contribute to the literature by identifying a specific social skill deficit related to Internet addiction and by unveiling a psychological mechanism that explains this relationship, thus providing more concrete guidelines for practitioners to strengthen specific social skills that mitigate both perceived stress and Internet addiction. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.

  4. Laser-based pedestrian tracking in outdoor environments by multiple mobile robots.

    PubMed

    Ozaki, Masataka; Kakimuma, Kei; Hashimoto, Masafumi; Takahashi, Kazuhiko

    2012-10-29

    This paper presents an outdoors laser-based pedestrian tracking system using a group of mobile robots located near each other. Each robot detects pedestrians from its own laser scan image using an occupancy-grid-based method, and the robot tracks the detected pedestrians via Kalman filtering and global-nearest-neighbor (GNN)-based data association. The tracking data is broadcast to multiple robots through intercommunication and is combined using the covariance intersection (CI) method. For pedestrian tracking, each robot identifies its own posture using real-time-kinematic GPS (RTK-GPS) and laser scan matching. Using our cooperative tracking method, all the robots share the tracking data with each other; hence, individual robots can always recognize pedestrians that are invisible to any other robot. The simulation and experimental results show that cooperating tracking provides the tracking performance better than conventional individual tracking does. Our tracking system functions in a decentralized manner without any central server, and therefore, this provides a degree of scalability and robustness that cannot be achieved by conventional centralized architectures.

  5. Implementing Sustainability: The Behavioral-Institutional Dimension

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Malone, Elizabeth; Diamond, Richard C.; Wolfe, Amy K

    2013-01-01

    Organizations, both public and private sector, are increasingly pursuing strategies to reduce their energy use and increase sustainability. Whether these efforts are based on economic rationale, community spirit, environmental ethics, federal mandates, or other reasons, they predominantly feature strategies that rely on new technologies. If there is any focus on behavior change, it is typically addressed to changing individual behavior. While we recognize the importance and limitations of the role of individual behavior in promoting sustainability goals, we are more interested in the role of institutional behavior. We have reviewed the small but growing literature on institutional behavior change, andmore » have identified eight evidence-based principles as a guide for federal agencies to take action. This article presents the principles and illustrates them with examples to suggest ways that they can serve as models for others.« less

  6. Enhancing quality improvements in cancer care through CME activities at a nationally recognized cancer center.

    PubMed

    Uemura, Marc; Morgan, Robert; Mendelsohn, Mary; Kagan, Jean; Saavedra, Crystal; Leong, Lucille

    2013-06-01

    Changing healthcare policy will undoubtedly affect the healthcare environment in which providers function. The current Fee for Service reimbursement model will be replaced by Value-Based Purchasing, where higher quality and more efficient care will be emphasized. Because of this, large healthcare organizations and individual providers must adapt to incorporate performance outcomes into patient care. Here, we present a Continuing Medical Education (CME)-based initiative at the City of Hope National Cancer Center that we believe can serve as a model for using CME as a value added component to achieving such a goal.

  7. Reaping benefits from intellectual capital.

    PubMed

    Weston, Marla J; Estrada, Nicolette A; Carrington, Jane

    2007-01-01

    The wealth and value of organizations are increasingly based on intellectual capital. Although acquiring talented individuals and investing in employee learning adds value to the organization, reaping the benefits of intellectual capital involves translating the wisdom of employees into reusable and sustained actions. This requires a culture that creates employee commitment, encourages learning, fosters sharing, and involves employees in decision making. An infrastructure to recognize and embed promising and best practices through social networks, evidence-based practice, customization of innovations, and use of information technology results in increased productivity, stronger financial performance, better patient outcomes, and greater employee and customer satisfaction.

  8. Policy toward individual economic holdings and private enterprises in agriculture, forestry, and fisheries, November 1988.

    PubMed

    1989-01-01

    On 29 November 1988, Viet Nam adopted a policy allowing individual economic holdings and private enterprises in the areas of agriculture, forestry, and fisheries. The policy recognizes the positive effect of such holdings and charges the state with creating favorable conditions for them. Ownership and inheritance rights are recognized, and all citizens are entitled to apply for permission to use certain land for business purposes. The production of exports is encouraged, and such enterprises may engage in financial transactions, including borrowing money.

  9. 26 CFR 1.5000A-3 - Exempt individuals.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... under section 501(a); (ii) Members of which share a common set of ethical or religious beliefs and share... recognized religious sects—(1) In general. An individual is an exempt individual for a month that includes a day on which the individual has in effect a religious conscience exemption certification described in...

  10. Blue petrels recognize the odor of their egg.

    PubMed

    Leclaire, Sarah; Bourret, Vincent; Bonadonna, Francesco

    2017-09-01

    Most studies on avian olfactory communication have focused on mate choice, and the importance of olfaction in subsequent nesting stages has been poorly explored. In particular, the role of olfactory cues in egg recognition has received little attention, despite eggs potentially being spread with parental odorous secretions known to elicit individual discrimination. Here, we used behavioral choice tests to determine whether female blue petrels ( Halobaena caerulea ) can discriminate the odor of their own egg from the odor of a conspecific egg. Females preferentially approached the odor of their own egg, suggesting that blue petrels can recognize their own egg using odor cues. This finding raises the question of the adaptive value of this mechanism, and may inspire further research on odor-based egg discrimination in species suffering brood parasitism. © 2017. Published by The Company of Biologists Ltd.

  11. Promoting Indian Library Use. Guide Number 7.

    ERIC Educational Resources Information Center

    Townley, Charles T.

    Individuals, organizations, and American Indian tribes are rapidly recognizing the value of libraries. They are recognizing that libraries and the information services which they offer are necessary to meet Indian goals. Specific sensitivity to Indian ways and alternatives is just developing as library and information services develop in Indian…

  12. The Use of Recognition in Group Decision-Making

    ERIC Educational Resources Information Center

    Reimer, Torsten; Katsikopoulos, Konstantinos V.

    2004-01-01

    Goldstein and Gigerenzer (2002) [Models of ecological rationality: The recognition heuristic. "Psychological Review," 109 (1), 75-90] found evidence for the use of the recognition heuristic. For example, if an individual recognizes only one of two cities, they tend to infer that the recognized city has a larger population. A prediction…

  13. The Influence of Non-Epistemic Features of Settings on Epistemic Cognition

    ERIC Educational Resources Information Center

    Kawasaki, Jarod N.; DeLiema, David J.; Sandoval, William A.

    2014-01-01

    Situated theories of learning recognize the rules, tools, goals, and communities within which activities develop. Similarly, situated theories of epistemic cognition recognize that individuals' ideas about knowledge are tentative and dependent on particular contexts. In this study, we bring these frameworks together and qualitatively examine how…

  14. Great Apes' Capacities to Recognize Relational Similarity

    ERIC Educational Resources Information Center

    Haun, Daniel B. M.; Call, Josep

    2009-01-01

    Recognizing relational similarity relies on the ability to understand that defining object properties might not lie in the objects individually, but in the relations of the properties of various object to each other. This aptitude is highly relevant for many important human skills such as language, reasoning, categorization and understanding…

  15. Creating a climate for excellence.

    PubMed

    Lancaster, J

    1985-01-01

    Some people are motivated to achieve in a manner consistent with the goals of their organization while others pursue individual goals. The attitudes people hold determine their behavior. Therefore, the manager is charged with creating an environment that fosters employee commitment to organizational goals. To create a climate for achievement, managers must recognize that all employees want recognition. Employees perform more effectively when they understand the goals of the organization, know what is expected of them, and are part of a system that includes feedback and reinforcement. Generally, people perform more effectively in an environment with minimal threat and punishment; individual responsibility should be encouraged, rewards based on results, and a climate of trust and open communication should prevail.

  16. Colored halos around faces and emotion-evoked colors: A new form of synesthesia

    PubMed Central

    Ramachandran, Vilayanur S.; Miller, Luke; Livingstone, Margaret S.; Brang, David

    2013-01-01

    The claim that some individuals see colored halos or auras around faces has long been part of popular folklore. Here we report on a 23-year-old man (subject TK) diagnosed with Asperger’s disorder, who began to consistently experience colors around individuals at the age of 10. TK’s colors are based on the individual’s identity and emotional connotation. We interpret these experiences as a form of synesthesia, and confirm their authenticity through a target detection paradigm. Additionally, we investigate TK’s claim that emotions evoke highly specific colors, allowing him, despite his Asperger’s, to introspect on emotions and recognize them in others. PMID:22115465

  17. Development of the Communication Complexity Scale

    ERIC Educational Resources Information Center

    Brady, Nancy C.; Fleming, Kandace; Thiemann-Bourque, Kathy; Olswang, Lesley; Dowden, Patricia; Saunders, Muriel D.; Marquis, Janet

    2012-01-01

    Purpose: Accurate description of an individual's communication status is critical in both research and practice. Describing the communication status of individuals with severe intellectual and developmental disabilities is difficult because these individuals often communicate with presymbolic means that may not be readily recognized. Our goal was…

  18. Challenges in detecting drowsiness based on driver’s behavior

    NASA Astrophysics Data System (ADS)

    Triyanti, V.; Iridiastadi, H.

    2017-12-01

    Drowsiness while driving has been a critical issue within the context of transportation safety. A number of approaches have been developed to reduce the risks of drowsy drivers. The mechanisms in detecting fatigue and sleepiness while driving has been categorized into three broad approaches, including vehicle-based, physiological-based, and behavior-based approaches. This paper will discuss recent studies in recognizing drowsy drivers based on their behaviors, particularly changes in eyes and facial characteristics. This paper will also address challenges in capturing aspects of natural expressions, driver responses, behavior, and task environment associated with sleepiness. Additionally, a number of technical aspects should be seriously considered, including correctly capturing face and eye characteristics from unwanted movements, unsuitable task environments, technological limitations, and individual differences.

  19. Communication-based services for persons with severe disabilities in schools: a survey of speech-language pathologists.

    PubMed

    Siegel, Ellin B; Maddox, Laura L; Ogletree, Billy T; Westling, David L

    2010-01-01

    Speech-language pathologists in school settings were surveyed with an instrument created from the National Joint Committee for the Communication Needs of Persons with Severe Disabilities' quality indicators self-assessment tool. Participants valued practice indicators of quality communication assessment and intervention to a higher degree than their actual practice. These findings appear to suggest that SLPs may not provide best practice services to individuals with severe disabilities. Suggestions for enhancing inservice training and intervention practices of SLPs and team members who work with individuals with severe disabilities are provided. The reader will be able to; (1) understand the value of using the NJC quality indicators to guide SLP practices with individuals with severe disabilities in schools; (2) recognize that research indicates that SLPs working with individuals with severe disabilities in schools may not provide best practice services to the extent that they value these practices; (3) discuss possible strategies to increase the quality of services provided to individuals with severe disabilities in schools.

  20. Choosing employment: factors that impact employment decisions for individuals with intellectual disability.

    PubMed

    Timmons, Jaimie Ciulla; Hall, Allison Cohen; Bose, Jennifer; Wolfe, Ashley; Winsor, Jean

    2011-08-01

    Little is known about the factors that shape the employment-related decisions of individuals with intellectual and/or developmental disabilities. Findings from qualitative interviews with individuals, their family members, and employment-support professionals from four community rehabilitation providers throughout Massachusetts were reported. Recognizing the value of participatory action research, we also included a co-researcher with intellectual disability who participated in all facets of the research process. Findings revealed a collection of people and factors considered influential in employment-related decision-making. The family in the formative years, school-based staff and early employment experiences, the culture of the community rehabilitation providers, the job developer, and personal preferences all influenced participants' decisions. Through understanding these persuasive elements, we offer recommendations to those in the intellectual and developmental disabilities field to optimize employment choices and outcomes.

  1. Hypo- and Hyperglycemic Alarms

    PubMed Central

    Howsmon, Daniel; Bequette, B. Wayne

    2015-01-01

    Soon after the discovery that insulin regulates blood glucose by Banting and Best in 1922, the symptoms and risks associated with hypoglycemia became widely recognized. This article reviews devices to warn individuals of impending hypo- and hyperglycemia; biosignals used by these devices include electroencephalography, electrocardiography, skin galvanic resistance, diabetes alert dogs, and continuous glucose monitors (CGMs). While systems based on other technology are increasing in performance and decreasing in size, CGM technology remains the best method for both reactive and predictive alarming of hypo- or hyperglycemia. PMID:25931581

  2. Stepping Up Together: Financing Early Care and Education in the 21st Century. Volume 2. Proceedings for "Making It Economically Viable: Financing Early Care and Education." A Working Meeting (Santa Cruz, California, March 3-5, 1999).

    ERIC Educational Resources Information Center

    National Association of Child Advocates, Washington, DC.

    The need for an adequate financial base for the future of quality early care and education (ECE) for young children is being increasingly recognized. This document presents the proceedings for a 1999 working meeting of individuals from diverse fields to identify and explore possible actions related to financing ECE for children birth through 5…

  3. DAISY Nurses-Recognizing Clinical Expertise Through Certification.

    PubMed

    Sweeney, Cynthia Divens

    2018-04-01

    The DAISY Foundation is dedicated to recognizing nurses who provide compassionate, skilled, and extraordinary nursing care. Nominations for The DAISY Award are typically submitted in the form of a story. Stories are an opportunity to share with others what compassionate and extraordinary nursing care looks like and to recognize the individual nurses who provide that care. Clinical competence delivered with compassion is a hallmark of DAISY Award recipients. Professional certification provides an additional form of recognition of a nurse's clinical competence.

  4. Believing is Seeing: Visual Conventions in Barr's Classification of the "Feeble-Minded"

    ERIC Educational Resources Information Center

    Elks, Martin A.

    2004-01-01

    The eugenics era (c. 1900?1930) produced a strong desire among mental retardation professionals to recognize and control "the feeble-minded." Some eugenicists believed it was possible to classify individuals visually by learning to recognize what they believed to be observable characteristics of idiocy and imbecility. In this paper I used…

  5. Probabilistic Phonotactics as a Cue for Recognizing Spoken Cantonese Words in Speech

    ERIC Educational Resources Information Center

    Yip, Michael C. W.

    2017-01-01

    Previous experimental psycholinguistic studies suggested that the probabilistic phonotactics information might likely to hint the locations of word boundaries in continuous speech and hence posed an interesting solution to the empirical question on how we recognize/segment individual spoken word in speech. We investigated this issue by using…

  6. Teaching corner: child family health international : the ethics of asset-based global health education programs.

    PubMed

    Evert, Jessica

    2015-03-01

    Child Family Health International (CFHI) is a U.S.-based nonprofit, nongovernmental organization (NGO) that has more than 25 global health education programs in seven countries annually serving more than 600 interprofessional undergraduate, graduate, and postgraduate participants in programs geared toward individual students and university partners. Recognized by Special Consultative Status with the United Nations Economic and Social Council (ECOSOC), CFHI utilizes an asset-based community engagement model to ensure that CFHI's programs challenge, rather than reinforce, historical power imbalances between the "Global North" and "Global South." CFHI's programs are predicated on ethical principles including reciprocity, sustainability, humility, transparency, nonmaleficence, respect for persons, and social justice.

  7. Personalized recommendation via unbalance full-connectivity inference

    NASA Astrophysics Data System (ADS)

    Ma, Wenping; Ren, Chen; Wu, Yue; Wang, Shanfeng; Feng, Xiang

    2017-10-01

    Recommender systems play an important role to help us to find useful information. They are widely used by most e-commerce web sites to push the potential items to individual user according to purchase history. Network-based recommendation algorithms are popular and effective in recommendation, which use two types of elements to represent users and items respectively. In this paper, based on consistence-based inference (CBI) algorithm, we propose a novel network-based algorithm, in which users and items are recognized with no difference. The proposed algorithm also uses information diffusion to find the relationship between users and items. Different from traditional network-based recommendation algorithms, information diffusion initializes from users and items, respectively. Experiments show that the proposed algorithm is effective compared with traditional network-based recommendation algorithms.

  8. Self-esteem recognition based on gait pattern using Kinect.

    PubMed

    Sun, Bingli; Zhang, Zhan; Liu, Xingyun; Hu, Bin; Zhu, Tingshao

    2017-10-01

    Self-esteem is an important aspect of individual's mental health. When subjects are not able to complete self-report questionnaire, behavioral assessment will be a good supplement. In this paper, we propose to use gait data collected by Kinect as an indicator to recognize self-esteem. 178 graduate students without disabilities participate in our study. Firstly, all participants complete the 10-item Rosenberg Self-Esteem Scale (RSS) to acquire self-esteem score. After completing the RRS, each participant walks for two minutes naturally on a rectangular red carpet, and the gait data are recorded using Kinect sensor. After data preprocessing, we extract a few behavioral features to train predicting model by machine learning. Based on these features, we build predicting models to recognize self-esteem. For self-esteem prediction, the best correlation coefficient between predicted score and self-report score is 0.45 (p<0.001). We divide the participants according to gender, and for males, the correlation coefficient is 0.43 (p<0.001), for females, it is 0.59 (p<0.001). Using gait data captured by Kinect sensor, we find that the gait pattern could be used to recognize self-esteem with a fairly good criterion validity. The gait predicting model can be taken as a good supplementary method to measure self-esteem. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. Can an economist find happiness setting public utility rates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kahn, A.E.

    Alfred E. Kahn describes his applications of economic theories to rate level regulatory policies during his career as a public utilities regulator. Two shifts in regulatory thinking have responded to the intent to have rates set to reflect rising costs that will be occuring while the rates are in effect rather than on past costs and have recognized that varying the allowable rate of return can be as effective as changing the rate base. Pressures have been exerted on economists to place too much emphasis on regulatory lag, full-cost pricing, sunk cost, and other factors affecting capital formation. A rationalmore » policy recognizes differences between the needs of individual companies to raise capital and the variations that occur during a given accounting period. Rates based on trends that recognize returns over a time span is one solution. Anticipated cost increases have been included in rate levels so that automatic cost adjustments can be made during times of inflation. Because of increases in the marginal cost of capital, regulators must decide how to selectively vary cash flow during construction periods in a way that will give adequate signals to consumers. Situations in which a water company is associated with a real estate developer can avoid a double recovery of investment by granting rate increases in relation to cost over time.« less

  10. Genome-Level Determination of Plasmodium falciparum Blood-Stage Targets of Malarial Clinical Immunity in the Peruvian Amazon

    PubMed Central

    Torres, Katherine J.; Castrillon, Carlos E.; Moss, Eli L.; Saito, Mayuko; Tenorio, Roy; Molina, Douglas M.; Davies, Huw; Neafsey, Daniel E.; Felgner, Philip; Vinetz, Joseph M.; Gamboa, Dionicia

    2015-01-01

    Background. Persons with blood-stage Plasmodium falciparum parasitemia in the absence of symptoms are considered to be clinically immune. We hypothesized that asymptomatic subjects with P. falciparum parasitemia would differentially recognize a subset of P. falciparum proteins on a genomic scale. Methods and Findings. Compared with symptomatic subjects, sera from clinically immune, asymptomatically infected individuals differentially recognized 51 P. falciparum proteins, including the established vaccine candidate PfMSP1. Novel, hitherto unstudied hypothetical proteins and other proteins not previously recognized as potential vaccine candidates were also differentially recognized. Genes encoding the proteins differentially recognized by the Peruvian clinically immune individuals exhibited a significant enrichment of nonsynonymous nucleotide variation, an observation consistent with these genes undergoing immune selection. Conclusions. A limited set of P. falciparum protein antigens was associated with the development of naturally acquired clinical immunity in the low-transmission setting of the Peruvian Amazon. These results imply that, even in a low-transmission setting, an asexual blood-stage vaccine designed to reduce clinical malaria symptoms will likely need to contain large numbers of often-polymorphic proteins, a finding at odds with many current efforts in the design of vaccines against asexual blood-stage P. falciparum. PMID:25381370

  11. Osteology, Phylogeny, Taphonomy, and Ontogenetic Histology of Oryctodromeus cubicularis, from the Middle Cretaceous (Albian-Cenomanian) of Montana and Idaho

    NASA Astrophysics Data System (ADS)

    Krumenacker, L. J.

    Oryctodromeus is a small bipedal dinosaur known from middle Cretaceous (95-100 My) Wayan Formation of Idaho and the Vaughn Member of the Blackleaf Formation of Montana. This taxon is hypothesized to be a burrowing dinosaur, which cared for its young within these burrows. This dissertation is a broad three-part treatment of this taxon, and excepting the introductory and concluding chapters this dissertation consists of three main chapters. Chapter two describes the osteology and phylogenetic relationships of this animal. Notable features of the Oryctodromeus skeleton described include a network of ossified tendons along the vertebral column that completely ensheath the tail, a long tail that forms more than half the length of the animal, and unusual femoral heads whose morphology may be related to burrowing behavior. The first full skeletal and skull reconstructions of this animal are presented. Chapter three investigates patterns of preservation of Oryctodromeus. Data suggests that preservation of single to multiple individuals of this taxon typically occurred in burrows that may be difficult to impossible to recognize in the fossil record. New examples of burrows from Oryctodromeus from the Vaughn and Wayan, as well as additional evidence for social behavior, are also described. A third chapter details the ontogenetic histology, growth rates and patterns of skeletal fusion based on seven limb elements (femora and tibiae) from different individuals. Based on the data in this dissertation, three growth stages can be recognized in Oryctodromeus based on bone histology. Juveniles are defined by more rapidly growing fibrolamellar tissue, sub-adults are defined by a cortex of inner fibrolamellar tissue and outer zonal parallel fibered tissue, and near-adult individuals have tissue similar to sub adults with dense avascular bone in the outermost cortex that signals a decrease in growth rate. LAG's suggest a minimum age of six to seven years for more mature individuals. Patterns of neurocentral fusion in Oryctodromeus appear similar to those of crocodylians and some other small ornithischians, while the growth rates of Oryctodromeus appear slower than those of some dinosaurs, but similar to taxa such as Orodromeus and Tenontosaurus.

  12. [Venous thromboembolism: an urgent call for action].

    PubMed

    Páramo, José A; Lecumberri, Ramón

    2009-10-17

    Thousands of individuals suffer from deep vein thrombosis (DVT) all over the world, and many will die from its main complication, pulmonary embolism (PE). An important problem is that the diagnose is easy to overlook because the signs and symptoms are often difficult to recognize. Why do DVT and PE remain such a serious problem, particularly given the availability of effective strategies for preventing and treating them? The answer lays primarily in the failure to consistently use evidence-based interventions in high-risk individuals and in the lack of adherence to the different prophylactic interventions. In order to impact the incidence and burden of DVT/PE and increase public awareness, implementation of electronic alerts and evidence-based approaches, and scientific translational research are required. The commitment of all levels of governments as well as public and private institutions will be crucial to reduce the incidence of DVT, a leading cause of death.

  13. High photoresponse of individual WS2 nanowire-nanoflake hybrid materials

    NASA Astrophysics Data System (ADS)

    Asres, Georgies Alene; Järvinen, Topias; Lorite, Gabriela S.; Mohl, Melinda; Pitkänen, Olli; Dombovari, Aron; Tóth, Geza; Spetz, Anita Lloyd; Vajtai, Robert; Ajayan, Pulickel M.; Lei, Sidong; Talapatra, Saikat; Kordas, Krisztian

    2018-06-01

    van der Waals solids have been recognized as highly photosensitive materials that compete conventional Si and compound semiconductor based devices. While 2-dimensional nanosheets of single and multiple layers and 1-dimensional nanowires of molybdenum and tungsten chalcogenides have been studied, their nanostructured derivatives with complex morphologies are not explored yet. Here, we report on the electrical and photosensitive properties of WS2 nanowire-nanoflake hybrid materials we developed lately. We probe individual hybrid nanostructured particles along the structure using focused ion beam deposited Pt contacts. Further, we use conductive atomic force microscopy to analyze electrical behavior across the nanostructure in the transverse direction. The electrical measurements are complemented by in situ laser beam illumination to explore the photoresponse of the nanohybrids in the visible optical spectrum. Photodetectors with responsivity up to ˜0.4 AW-1 are demonstrated outperforming graphene as well as most of the other transition metal dichalcogenide based devices.

  14. An investigation of the effect of race-based social categorization on adults' recognition of emotion.

    PubMed

    Reyes, B Nicole; Segal, Shira C; Moulson, Margaret C

    2018-01-01

    Emotion recognition is important for social interaction and communication, yet previous research has identified a cross-cultural emotion recognition deficit: Recognition is less accurate for emotions expressed by individuals from a cultural group different than one's own. The current study examined whether social categorization based on race, in the absence of cultural differences, influences emotion recognition in a diverse context. South Asian and White Canadians in the Greater Toronto Area completed an emotion recognition task that required them to identify the seven basic emotional expressions when posed by members of the same two groups, allowing us to tease apart the contributions of culture and social group membership. Contrary to our hypothesis, there was no mutual in-group advantage in emotion recognition: Participants were not more accurate at recognizing emotions posed by their respective racial in-groups. Both groups were more accurate at recognizing expressions when posed by South Asian faces, and White participants were more accurate overall compared to South Asian participants. These results suggest that in a diverse environment, categorization based on race alone does not lead to the creation of social out-groups in a way that negatively impacts emotion recognition.

  15. An investigation of the effect of race-based social categorization on adults’ recognition of emotion

    PubMed Central

    Reyes, B. Nicole; Segal, Shira C.

    2018-01-01

    Emotion recognition is important for social interaction and communication, yet previous research has identified a cross-cultural emotion recognition deficit: Recognition is less accurate for emotions expressed by individuals from a cultural group different than one’s own. The current study examined whether social categorization based on race, in the absence of cultural differences, influences emotion recognition in a diverse context. South Asian and White Canadians in the Greater Toronto Area completed an emotion recognition task that required them to identify the seven basic emotional expressions when posed by members of the same two groups, allowing us to tease apart the contributions of culture and social group membership. Contrary to our hypothesis, there was no mutual in-group advantage in emotion recognition: Participants were not more accurate at recognizing emotions posed by their respective racial in-groups. Both groups were more accurate at recognizing expressions when posed by South Asian faces, and White participants were more accurate overall compared to South Asian participants. These results suggest that in a diverse environment, categorization based on race alone does not lead to the creation of social out-groups in a way that negatively impacts emotion recognition. PMID:29474367

  16. What do Different Beliefs Tell us? An Examination of Factual, Opinion-Based, and Religious Beliefs

    PubMed Central

    Heiphetz, Larisa; Spelke, Elizabeth S.; Harris, Paul L.; Banaji, Mahzarin R.

    2014-01-01

    Children and adults differentiate statements of religious belief from statements of fact and opinion, but the basis of that differentiation remains unclear. Across three experiments, adults and 8-10-year-old children heard statements of factual, opinion-based, and religious belief. Adults and children judged that statements of factual belief revealed more about the world, statements of opinion revealed more about individuals, and statements of religious belief provided information about both. Children—unlike adults—judged that statements of religious belief revealed more about the world than the believer. These results led to three conclusions. First, judgments concerning the relative amount of information statements of religious belief provide about individuals change across development, perhaps because adults have more experience with diversity. Second, recognizing that statements of religious belief provide information about both the world and the believer does not require protracted learning. Third, statements of religious belief are interpreted as amalgams of factual and opinion-based statements. PMID:24748720

  17. What do Different Beliefs Tell us? An Examination of Factual, Opinion-Based, and Religious Beliefs.

    PubMed

    Heiphetz, Larisa; Spelke, Elizabeth S; Harris, Paul L; Banaji, Mahzarin R

    2014-04-01

    Children and adults differentiate statements of religious belief from statements of fact and opinion, but the basis of that differentiation remains unclear. Across three experiments, adults and 8-10-year-old children heard statements of factual, opinion-based, and religious belief. Adults and children judged that statements of factual belief revealed more about the world, statements of opinion revealed more about individuals, and statements of religious belief provided information about both. Children-unlike adults-judged that statements of religious belief revealed more about the world than the believer. These results led to three conclusions. First, judgments concerning the relative amount of information statements of religious belief provide about individuals change across development, perhaps because adults have more experience with diversity. Second, recognizing that statements of religious belief provide information about both the world and the believer does not require protracted learning. Third, statements of religious belief are interpreted as amalgams of factual and opinion-based statements.

  18. Recognizing the value of assistance dogs in society.

    PubMed

    Audrestch, Hilary M; Whelan, Chantelle T; Grice, David; Asher, Lucy; England, Gary C W; Freeman, Sarah L

    2015-10-01

    Assistance dogs are specially trained to undertake a variety of tasks to help individuals with disabilities. This review gives an overview of the different types of assistance dogs in the UK, including guide dogs, hearing dogs, mobility assistance dogs, service dogs and dual-purpose dogs. The literature describes many benefits of assistance dogs, including their impact on physical wellbeing and safety of their 'owners,' as well as on psychological wellbeing and social inclusion. The role of assistance dogs in society is widely recognized by the public, but is not currently acknowledged in government social policy. The current evidence on the benefits of assistance dogs is limited by the type and scale of current research. This article highlights the need for independent funding for high quality research to enable social care and policy makers to make evidence-based decisions on the value of assistance dogs to people with disabilities. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. The effects of monitoring environment on problem-solving performance.

    PubMed

    Laird, Brian K; Bailey, Charles D; Hester, Kim

    2018-01-01

    While effective and efficient solving of everyday problems is important in business domains, little is known about the effects of workplace monitoring on problem-solving performance. In a laboratory experiment, we explored the monitoring environment's effects on an individual's propensity to (1) establish pattern solutions to problems, (2) recognize when pattern solutions are no longer efficient, and (3) solve complex problems. Under three work monitoring regimes-no monitoring, human monitoring, and electronic monitoring-114 participants solved puzzles for monetary rewards. Based on research related to worker autonomy and theory of social facilitation, we hypothesized that monitored (versus non-monitored) participants would (1) have more difficulty finding a pattern solution, (2) more often fail to recognize when the pattern solution is no longer efficient, and (3) solve fewer complex problems. Our results support the first two hypotheses, but in complex problem solving, an interaction was found between self-assessed ability and the monitoring environment.

  20. Individual Differences in Sleep Timing Relate to Melanopsin-Based Phototransduction in Healthy Adolescents and Young Adults.

    PubMed

    van der Meijden, Wisse P; Van Someren, Jamie L; Te Lindert, Bart H W; Bruijel, Jessica; van Oosterhout, Floor; Coppens, Joris E; Kalsbeek, Andries; Cajochen, Christian; Bourgin, Patrice; Van Someren, Eus J W

    2016-06-01

    Individual differences in sleep timing have been widely recognized and are of particular relevance in adolescents and young adults who often show mild to severely delayed sleep. The biological mechanisms underlying the between-subject variance remain to be determined. Recent human genetics studies showed an association between sleep timing and melanopsin gene variation, but support for functional effects on downstream pathways and behavior was not demonstrated before. We therefore investigated the association between the autonomic (i.e., pupil diameter) and behavioral (i.e., sleep timing) readouts of two different downstream brain areas, both affected by the same melanopsin-dependent retinal phototransduction: the olivary pretectal nucleus (OPN) and the suprachiasmatic nucleus (SCN). Our study population included 71 healthy individuals within an age range with known vulnerability to a delayed sleep phase (16.8-35.7 y, 37 males, 34 females). Pupillometry was performed to estimate functionality of the intrinsic melanopsin-signaling circuitry based on the OPN-mediated post-illumination pupil response (PIPR) to blue light. Sleep timing was quantified by estimating the SCN-mediated mid-sleep timing in three different ways in parallel: using a chronotype questionnaire, a sleep diary, and actigraphy. All three measures consistently showed that those individuals with a later mid-sleep timing had a more pronounced PIPR (0.03 < P < 0.05), indicating a stronger blue-light responsiveness of the intrinsic melanopsin-based phototransduction circuitry. Trait-like individual differences in the melanopsin phototransduction circuitry contribute to individual differences in sleep timing. Blue light-sensitive young individuals are more prone to delayed sleep. © 2016 Associated Professional Sleep Societies, LLC.

  1. Identifying individuality and variability in team tactics by means of statistical shape analysis and multilayer perceptrons.

    PubMed

    Jäger, Jörg M; Schöllhorn, Wolfgang I

    2012-04-01

    Offensive and defensive systems of play represent important aspects of team sports. They include the players' positions at certain situations during a match, i.e., when players have to be on specific positions on the court. Patterns of play emerge based on the formations of the players on the court. Recognition of these patterns is important to react adequately and to adjust own strategies to the opponent. Furthermore, the ability to apply variable patterns of play seems to be promising since they make it harder for the opponent to adjust. The purpose of this study is to identify different team tactical patterns in volleyball and to analyze differences in variability. Overall 120 standard situations of six national teams in women's volleyball are analyzed during a world championship tournament. Twenty situations from each national team are chosen, including the base defence position (start configuration) and the two players block with middle back deep (end configuration). The shapes of the defence formations at the start and end configurations during the defence of each national team as well as the variability of these defence formations are statistically analyzed. Furthermore these shapes data are used to train multilayer perceptrons in order to test whether artificial neural networks can recognize the teams by their tactical patterns. Results show significant differences between the national teams in both the base defence position at the start and the two players block with middle back deep at the end of the standard defence situation. Furthermore, the national teams show significant differences in variability of the defence systems and start-positions are more variable than the end-positions. Multilayer perceptrons are able to recognize the teams at an average of 98.5%. It is concluded that defence systems in team sports are highly individual at a competitive level and variable even in standard situations. Artificial neural networks can be used to recognize teams by the shapes of the players' configurations. These findings support the concept that tactics and strategy have to be adapted for the team and need to be flexible in order to be successful. Copyright © 2010 Elsevier B.V. All rights reserved.

  2. Expanding the foundation for personalized medicine: implications and challenges for dentistry.

    PubMed

    Garcia, I; Kuska, R; Somerman, M J

    2013-07-01

    Personalized medicine aims to individualize care based on a person's unique genetic, environmental, and clinical profile. Dentists and physicians have long recognized variations between and among patients, and have customized care based on each individual's health history, environment, and behavior. However, the sequencing of the human genome in 2003 and breakthroughs in regenerative medicine, imaging, and computer science redefined "personalized medicine" as clinical care that takes advantage of new molecular tools to facilitate highly precise health care based on an individual's unique genomic and molecular characteristics. Major investments in science bring a new urgency toward realizing the promise of personalized medicine; yet, many challenges stand in the way. In this article, we present an overview of the opportunities and challenges that influence the oral health community's full participation in personalized medicine. We highlight selected research advances that are solidifying the foundation of personalized oral health care, elaborate on their impact on dentistry, and explore obstacles toward their adoption into practice. It is our view that now is the time for oral health professionals, educators, students, researchers, and patients to engage fully in preparations for the arrival of personalized medicine as a means to provide quality, customized, and effective oral health care for all.

  3. Divide and Conquer-Based 1D CNN Human Activity Recognition Using Test Data Sharpening †

    PubMed Central

    Yoon, Sang Min

    2018-01-01

    Human Activity Recognition (HAR) aims to identify the actions performed by humans using signals collected from various sensors embedded in mobile devices. In recent years, deep learning techniques have further improved HAR performance on several benchmark datasets. In this paper, we propose one-dimensional Convolutional Neural Network (1D CNN) for HAR that employs a divide and conquer-based classifier learning coupled with test data sharpening. Our approach leverages a two-stage learning of multiple 1D CNN models; we first build a binary classifier for recognizing abstract activities, and then build two multi-class 1D CNN models for recognizing individual activities. We then introduce test data sharpening during prediction phase to further improve the activity recognition accuracy. While there have been numerous researches exploring the benefits of activity signal denoising for HAR, few researches have examined the effect of test data sharpening for HAR. We evaluate the effectiveness of our approach on two popular HAR benchmark datasets, and show that our approach outperforms both the two-stage 1D CNN-only method and other state of the art approaches. PMID:29614767

  4. Divide and Conquer-Based 1D CNN Human Activity Recognition Using Test Data Sharpening.

    PubMed

    Cho, Heeryon; Yoon, Sang Min

    2018-04-01

    Human Activity Recognition (HAR) aims to identify the actions performed by humans using signals collected from various sensors embedded in mobile devices. In recent years, deep learning techniques have further improved HAR performance on several benchmark datasets. In this paper, we propose one-dimensional Convolutional Neural Network (1D CNN) for HAR that employs a divide and conquer-based classifier learning coupled with test data sharpening. Our approach leverages a two-stage learning of multiple 1D CNN models; we first build a binary classifier for recognizing abstract activities, and then build two multi-class 1D CNN models for recognizing individual activities. We then introduce test data sharpening during prediction phase to further improve the activity recognition accuracy. While there have been numerous researches exploring the benefits of activity signal denoising for HAR, few researches have examined the effect of test data sharpening for HAR. We evaluate the effectiveness of our approach on two popular HAR benchmark datasets, and show that our approach outperforms both the two-stage 1D CNN-only method and other state of the art approaches.

  5. Moderate Effects of Same-Sex Legislation on Dependent Employer-Based Insurance Coverage Among Sexual Minorities.

    PubMed

    Tran, Linda Diem

    2016-12-01

    A difference-in-difference approach was used to compare the effects of same-sex domestic partnership, civil union, and marriage policies on same- and different-sex partners who could have benefitted from their partners' employer-based insurance (EBI) coverage. Same-sex partners had 78% lower odds (Marginal Effect = -21%) of having EBI compared with different-sex partners, adjusting for socioeconomic and health-related factors. Same-sex partners living in states that recognized same-sex marriage or domestic partnership had 89% greater odds of having EBI compared with those in states that did not recognize same-sex unions (ME = 5%). The impact of same-sex legislation on increasing take-up of dependent EBI coverage among lesbians, gay men, and bisexual individuals was modest, and domestic partnership legislation was equally as effective as same-sex marriage in increasing same-sex partner EBI coverage. Extending dependent EBI coverage to same-sex partners can mitigate gaps in coverage for a segment of the lesbians, gay men, and bisexual population but will not eliminate them. © The Author(s) 2016.

  6. The ACTIVATE study: results from a group-randomized controlled trial comparing a traditional worksite health promotion program with an activated consumer program.

    PubMed

    Terry, Paul E; Fowles, Jinnet Briggs; Xi, Min; Harvey, Lisa

    2011-01-01

    PURPOSE. This study compares a traditional worksite-based health promotion program with an activated consumer program and a control program DESIGN. Group randomized controlled trial with 18-month intervention. SETTING. Two large Midwestern companies. SUBJECTS. Three hundred and twenty employees (51% response). INTERVENTION. The traditional health promotion intervention offered population-level campaigns on physical activity, nutrition, and stress management. The activated consumer intervention included population-level campaigns for evaluating health information, choosing a health benefits plan, and understanding the risks of not taking medications as prescribed. The personal development intervention (control group) offered information on hobbies. The interventions also offered individual-level coaching for high risk individuals in both active intervention groups. MEASURES. Health risk status, general health status, consumer activation, productivity, and the ability to evaluate health information. ANALYSIS. Multivariate analyses controlled for baseline differences among the study groups. RESULTS. At the population level, compared with baseline performance, the traditional health promotion intervention improved health risk status, consumer activation, and the ability to recognize reliable health websites. Compared with baseline performance, the activated consumer intervention improved consumer activation, productivity, and the ability to recognize reliable health websites. At the population level, however, only the activated consumer intervention improved any outcome more than the control group did; that outcome was consumer activation. At the individual level for high risk individuals, both traditional health coaching and activated consumer coaching positively affected health risk status and consumer activation. In addition, both coaching interventions improved participant ability to recognize a reliable health website. Consumer activation coaching also significantly improved self-reported productivity. CONCLUSION. An effective intervention can change employee health risk status and activation both at the population level and at the individual high risk level. However, program engagement at the population level was low, indicating that additional promotional strategies, such as greater use of incentives, need to be examined. Less intensive coaching can be as effective as more intensive, albeit both interventions produced modest behavior change and retention in the consumer activation arm was most difficult. Further research is needed concerning recruitment and retention methods that will enable populations to realize the full potential of activated consumerism.

  7. A recovery-based outreach program in rural Victoria.

    PubMed

    Prabhu, Radha; Browne, Mark Oakley

    2007-04-01

    A recovery-based outreach program for people with severe mental illness in regional Victoria is described. The paper covers a description of the program, the services provided and outcomes achieved. The program emphasized active collaboration between patients and clinicians as outlined in the collaborative recovery model and recognized that recovery from mental illness is an individual, personal process. The program provided service to 108 people over 3 years and had a positive impact on clinicians, patients and carers. The benefits of recovery orientation, multidisciplinary teams, collaborative relationships and carer involvement are discussed. The paper highlights the need for a focus on recovery and comprehensive care for people with severe mental illness.

  8. How schizophrenia develops: cognitive and brain mechanisms underlying onset of psychosis

    PubMed Central

    Cannon, Tyrone D.

    2015-01-01

    Identifying cognitive and neural mechanisms involved in the development of schizophrenia requires longitudinal observation of individuals prior to onset. Here recent studies of prodromal individuals who progress to full psychosis are briefly reviewed in relation to models of schizophrenia pathophysiology. Together, this body of work suggests that disruption in brain connectivity, driven primarily by a progressive reduction in dendritic spines on cortical pyramidal neurons, may represent a key triggering mechanism. The earliest disruptions appear to be in circuits involved in referencing experiences according to time, place, and agency, which may result in a failure to recognize particular cognitions as self-generated or to constrain interpretations of the meaning of events based on prior experiences, providing the scaffolding for faulty reality testing. PMID:26493362

  9. Learning Activity Models for Multiple Agents in a Smart Space

    NASA Astrophysics Data System (ADS)

    Crandall, Aaron; Cook, Diane J.

    With the introduction of more complex intelligent environment systems, the possibilities for customizing system behavior have increased dramatically. Significant headway has been made in tracking individuals through spaces using wireless devices [1, 18, 26] and in recognizing activities within the space based on video data (see chapter by Brubaker et al. and [6, 8, 23]), motion sensor data [9, 25], wearable sensors [13] or other sources of information [14, 15, 22]. However, much of the theory and most of the algorithms are designed to handle one individual in the space at a time. Resident tracking, activity recognition, event prediction, and behavior automation becomes significantly more difficult for multi-agent situations, when there are multiple residents in the environment.

  10. Natural antibody responses to the capsid protein in sera of Dengue infected patients from Sri Lanka.

    PubMed

    Nadugala, Mahesha N; Jeewandara, Chandima; Malavige, Gathsaurie N; Premaratne, Prasad H; Goonasekara, Charitha L

    2017-01-01

    This study aims to characterize the antigenicity of the Capsid (C) protein and the human antibody responses to C protein from the four dengue virus (DENV) serotypes. Parker hydrophilicity prediction, Emini surface accessibility prediction and Karplus & Schulz flexibility predictions were used to bioinformatically characterize antigenicity. The human antibody response to C protein was assessed by ELISA using immune sera and an array of overlapping DENV2 C peptides. DENV2 C protein peptides P1 (located on C protein at 2-18 a.a), P11 (79-95 a.a) and P12 (86-101 a.a) were recognized by most individuals exposed to infections with only one of the 4 DENV serotypes as well as people exposed to infections with two serotypes. These conserved peptide epitopes are located on the amino (1-40 a.a) and carboxy (70-100 a.a) terminal regions of C protein, which were predicted to be antigenic using different bioinformatic tools. DENV2 C peptide P6 (39-56 a.a) was recognized by all individuals exposed to DENV2 infections, some individuals exposed to DENV4 infections and none of the individuals exposed to DENV1 or 3 infections. Thus, unlike C peptides P1, P11 and P12, which contain epitopes, recognized by DENV serotype cross-reactive antibodies, DENV2 peptide P6 contains an epitope that is preferentially recognized by antibodies in people exposed to this serotype compared to other serotypes. We discuss our results in the context of the known structure of C protein and recent work on the human B-cell response to DENV infection.

  11. 20 CFR 30.500 - What special statutory definitions apply to survivors under EEOICPA?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... individual for the 365 consecutive days immediately prior to the death of that individual. (2) Child or children includes a recognized natural child of a deceased covered Part B employee or deceased covered Part E employee, a stepchild who lived with that individual in a regular parent-child relationship, and...

  12. Enhancing the Emotion Recognition Skills of Individuals with Learning Disabilities: A Review of the Literature

    ERIC Educational Resources Information Center

    Wood, Pamela Margaret; Kroese, Biza Stenfert

    2007-01-01

    Background: It has been repeatedly demonstrated that individuals with intellectual disabilities experience significant difficulties in recognizing facial expressions of emotion. The aim of this review was to address whether such skills can be enhanced amongst individuals with intellectual disabilities. Materials and Methods: The PsychInfo database…

  13. The face you recognize may not be the one you saw: memory conjunction errors in individuals with or without learning disability.

    PubMed

    Danielsson, Henrik; Rönnberg, Jerker; Leven, Anna; Andersson, Jan; Andersson, Karin; Lyxell, Björn

    2006-06-01

    Memory conjunction errors, that is, when a combination of two previously presented stimuli is erroneously recognized as previously having been seen, were investigated in a face recognition task with drawings and photographs in 23 individuals with learning disability, and 18 chronologically age-matched controls without learning disability. Compared to the controls, individuals with learning disability committed significantly more conjunction errors, feature errors (one old and one new component), but had lower correct recognition, when the results were adjusted for different guessing levels. A dual-processing approach gained more support than a binding approach. However, neither of the approaches could explain all of the results. The results of the learning disability group were only partly related to non-verbal intelligence.

  14. Recognizing resilience: Learning from the effects of stress on the brain

    PubMed Central

    McEwen, Bruce S.; Gray, Jason D.; Nasca, Carla

    2014-01-01

    As the central organ of stress and adaptation to stressors, the brain plays a pivotal role in behavioral and physiological responses that may lead to successful adaptation or to pathophysiology and mental and physical disease. In this context, resilience can be defined as “achieving a positive outcome in the face of adversity”. Underlying this deceptively simple statement are several questions; first, to what extent is this ability limited to those environments that have shaped the individual or can it be more flexible; second, when in the life course does the brain develop capacity for flexibility for adapting positively to new challenges; and third, can such flexibility be instated in individuals where early life experiences have limited that capacity? Brain architecture continues to show plasticity throughout adult life and studies of gene expression and epigenetic regulation reveal a dynamic and ever-changing brain. The goal is to recognize those biological changes that underlie flexible adaptability, and to recognize gene pathways, epigenetic factors and structural changes that indicate lack of resilience leading to negative outcomes, particularly when the individual is challenged by new circumstances. Early life experiences determine individual differences in such capabilities via epigenetic pathways and laying down of brain architecture that determine the later capacity for flexible adaptation or the lack thereof. Reactivation of such plasticity in individuals lacking such resilience is a new challenge for research and practical application. Finally, sex differences in the plasticity of the brain are often overlooked and must be more fully investigated. PMID:25506601

  15. Call recognition and individual identification of fish vocalizations based on automatic speech recognition: An example with the Lusitanian toadfish.

    PubMed

    Vieira, Manuel; Fonseca, Paulo J; Amorim, M Clara P; Teixeira, Carlos J C

    2015-12-01

    The study of acoustic communication in animals often requires not only the recognition of species specific acoustic signals but also the identification of individual subjects, all in a complex acoustic background. Moreover, when very long recordings are to be analyzed, automatic recognition and identification processes are invaluable tools to extract the relevant biological information. A pattern recognition methodology based on hidden Markov models is presented inspired by successful results obtained in the most widely known and complex acoustical communication signal: human speech. This methodology was applied here for the first time to the detection and recognition of fish acoustic signals, specifically in a stream of round-the-clock recordings of Lusitanian toadfish (Halobatrachus didactylus) in their natural estuarine habitat. The results show that this methodology is able not only to detect the mating sounds (boatwhistles) but also to identify individual male toadfish, reaching an identification rate of ca. 95%. Moreover this method also proved to be a powerful tool to assess signal durations in large data sets. However, the system failed in recognizing other sound types.

  16. Systems and methods for biometric identification using the acoustic properties of the ear canal

    DOEpatents

    Bouchard, Ann Marie; Osbourn, Gordon Cecil

    1998-01-01

    The present invention teaches systems and methods for verifying or recognizing a person's identity based on measurements of the acoustic response of the individual's ear canal. The system comprises an acoustic emission device, which emits an acoustic source signal s(t), designated by a computer, into the ear canal of an individual, and an acoustic response detection device, which detects the acoustic response signal f(t). A computer digitizes the response (detected) signal f(t) and stores the data. Computer-implemented algorithms analyze the response signal f(t) to produce ear-canal feature data. The ear-canal feature data obtained during enrollment is stored on the computer, or some other recording medium, to compare the enrollment data with ear-canal feature data produced in a subsequent access attempt, to determine if the individual has previously been enrolled. The system can also be adapted for remote access applications.

  17. Untangling the Contribution of the Subcomponents of Working Memory to Mathematical Proficiency as Measured by the National Tests: A Study among Swedish Third Graders

    PubMed Central

    Wiklund-Hörnqvist, Carola; Jonsson, Bert; Korhonen, Johan; Eklöf, Hanna; Nyroos, Mikaela

    2016-01-01

    The aim with the present study was to examine the relationship between the subcomponents in working memory (WM) and mathematical performance, as measured by the National tests in a sample of 597 Swedish third-grade pupils. In line with compelling evidence of other studies, individual differences in WM capacity significantly predicted mathematical performance. Dividing the sample into four groups, based on their mathematical performance, revealed that mathematical ability can be conceptualized in terms of different WM profiles. Pupils categorized as High-math performers particularly differed from the other three groups in having a significant higher phonological ability. In contrast, pupils categorized as Low-math performers were particularly characterized by having a significant lower visuo-spatial ability. Findings suggest that it is important for educators to recognize and acknowledge individual differences in WM to support mathematical achievement at an individual level. PMID:27486413

  18. The Impact of Power on Information Processing Depends on Cultural Orientation

    PubMed Central

    Torelli, Carlos J.; Shavitt, Sharon

    2011-01-01

    Two studies show that different culturally based concepts of interpersonal power have distinct implications for information processing. People with a vertical individualist (VI) cultural orientation view power in personalized terms (power is for gaining status over and recognition by others), whereas people with a horizontal collectivist (HC) cultural orientation view power in socialized terms (power is for benefitting and helping others). The distinct goals associated with these power concepts are served by different mindsets, such as stereotyping others versus learning the individuating needs of others. Therefore, for high-VI individuals, making personalized power salient increases stereotyping in processing product information. That is, they recognize better information that is congruent with their prior product expectations, relative to their recognition of incongruent information. In contrast, for high-HC people, making socialized power salient increases individuating processes, characterized by better memory for incongruent information. PMID:21779130

  19. Bat wing biometrics: using collagen-elastin bundles in bat wings as a unique individual identifier.

    PubMed

    Amelon, Sybill K; Hooper, Sarah E; Womack, Kathryn M

    2017-05-29

    The ability to recognize individuals within an animal population is fundamental to conservation and management. Identification of individual bats has relied on artificial marking techniques that may negatively affect the survival and alter the behavior of individuals. Biometric systems use biological characteristics to identify individuals. The field of animal biometrics has expanded to include recognition of individuals based upon various morphologies and phenotypic variations including pelage patterns, tail flukes, and whisker arrangement. Biometric systems use 4 biologic measurement criteria: universality, distinctiveness, permanence, and collectability. Additionally, the system should not violate assumptions of capture-recapture methods that include no increased mortality or alterations of behavior. We evaluated whether individual bats could be uniquely identified based upon the collagen-elastin bundles that are visible with gross examination of their wings. We examined little brown bats ( Myotis lucifugus ), northern long-eared bats ( M. septentrionalis ), big brown bats ( Eptesicus fuscus ), and tricolored bats ( Perimyotis subflavus ) to determine whether the "wing prints" from the bundle network would satisfy the biologic measurement criteria. We evaluated 1,212 photographs from 230 individual bats comparing week 0 photos with those taken at weeks 3 or 6 and were able to confirm identity of individuals over time. Two blinded evaluators were able to successfully match 170 individuals in hand to photographs taken at weeks 0, 3, and 6. This study suggests that bats can be successfully re-identified using photographs taken at previous times. We suggest further evaluation of this methodology for use in a standardized system that can be shared among bat conservationists.

  20. Bat wing biometrics: using collagen–elastin bundles in bat wings as a unique individual identifier

    PubMed Central

    Hooper, Sarah E.; Womack, Kathryn M.

    2017-01-01

    Abstract The ability to recognize individuals within an animal population is fundamental to conservation and management. Identification of individual bats has relied on artificial marking techniques that may negatively affect the survival and alter the behavior of individuals. Biometric systems use biological characteristics to identify individuals. The field of animal biometrics has expanded to include recognition of individuals based upon various morphologies and phenotypic variations including pelage patterns, tail flukes, and whisker arrangement. Biometric systems use 4 biologic measurement criteria: universality, distinctiveness, permanence, and collectability. Additionally, the system should not violate assumptions of capture–recapture methods that include no increased mortality or alterations of behavior. We evaluated whether individual bats could be uniquely identified based upon the collagen–elastin bundles that are visible with gross examination of their wings. We examined little brown bats (Myotis lucifugus), northern long-eared bats (M. septentrionalis), big brown bats (Eptesicus fuscus), and tricolored bats (Perimyotis subflavus) to determine whether the “wing prints” from the bundle network would satisfy the biologic measurement criteria. We evaluated 1,212 photographs from 230 individual bats comparing week 0 photos with those taken at weeks 3 or 6 and were able to confirm identity of individuals over time. Two blinded evaluators were able to successfully match 170 individuals in hand to photographs taken at weeks 0, 3, and 6. This study suggests that bats can be successfully re-identified using photographs taken at previous times. We suggest further evaluation of this methodology for use in a standardized system that can be shared among bat conservationists. PMID:29674784

  1. Machine Learning Based Multi-Physical-Model Blending for Enhancing Renewable Energy Forecast -- Improvement via Situation Dependent Error Correction

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lu, Siyuan; Hwang, Youngdeok; Khabibrakhmanov, Ildar

    With increasing penetration of solar and wind energy to the total energy supply mix, the pressing need for accurate energy forecasting has become well-recognized. Here we report the development of a machine-learning based model blending approach for statistically combining multiple meteorological models for improving the accuracy of solar/wind power forecast. Importantly, we demonstrate that in addition to parameters to be predicted (such as solar irradiance and power), including additional atmospheric state parameters which collectively define weather situations as machine learning input provides further enhanced accuracy for the blended result. Functional analysis of variance shows that the error of individual modelmore » has substantial dependence on the weather situation. The machine-learning approach effectively reduces such situation dependent error thus produces more accurate results compared to conventional multi-model ensemble approaches based on simplistic equally or unequally weighted model averaging. Validation over an extended period of time results show over 30% improvement in solar irradiance/power forecast accuracy compared to forecasts based on the best individual model.« less

  2. Laser-Based Pedestrian Tracking in Outdoor Environments by Multiple Mobile Robots

    PubMed Central

    Ozaki, Masataka; Kakimuma, Kei; Hashimoto, Masafumi; Takahashi, Kazuhiko

    2012-01-01

    This paper presents an outdoors laser-based pedestrian tracking system using a group of mobile robots located near each other. Each robot detects pedestrians from its own laser scan image using an occupancy-grid-based method, and the robot tracks the detected pedestrians via Kalman filtering and global-nearest-neighbor (GNN)-based data association. The tracking data is broadcast to multiple robots through intercommunication and is combined using the covariance intersection (CI) method. For pedestrian tracking, each robot identifies its own posture using real-time-kinematic GPS (RTK-GPS) and laser scan matching. Using our cooperative tracking method, all the robots share the tracking data with each other; hence, individual robots can always recognize pedestrians that are invisible to any other robot. The simulation and experimental results show that cooperating tracking provides the tracking performance better than conventional individual tracking does. Our tracking system functions in a decentralized manner without any central server, and therefore, this provides a degree of scalability and robustness that cannot be achieved by conventional centralized architectures. PMID:23202171

  3. Stroke risk perception among participants of a stroke awareness campaign

    PubMed Central

    Kraywinkel, Klaus; Heidrich, Jan; Heuschmann, Peter U; Wagner, Markus; Berger, Klaus

    2007-01-01

    Background Subjective risk factor perception is an important component of the motivation to change unhealthy life styles. While prior studies assessed cardiovascular risk factor knowledge, little is known about determinants of the individual perception of stroke risk. Methods Survey by mailed questionnaire among 1483 participants of a prior public stroke campaign in Germany. Participants had been informed about their individual stroke risk based on the Framingham stroke risk score. Stroke risk factor knowledge, perception of lifetime stroke risk and risk factor status were included in the questionnaire, and the determinants of good risk factor knowledge and high stroke risk perception were identified using logistic regression models. Results Overall stroke risk factor knowledge was good with 67–96% of the participants recognizing established risk factors. The two exceptions were diabetes (recognized by 49%) and myocardial infarction (57%). Knowledge of a specific factor was superior among those affected by it. 13% of all participants considered themselves of having a high stroke risk, 55% indicated a moderate risk. All major risk factors contributed significantly to the perception of being at high stroke risk, but the effects of age, sex and education were non-significant. Poor self-rated health was additionally associated with high individual stroke risk perception. Conclusion Stroke risk factor knowledge was high in this study. The self perception of an increased stroke risk was associated with established risk factors as well as low perception of general health. PMID:17371603

  4. The future of capitation: the physician role in managing change in practice.

    PubMed

    Goodson, J D; Bierman, A S; Fein, O; Rask, K; Rich, E C; Selker, H P

    2001-04-01

    Capitation-based reimbursement significantly influences the practice of medicine. As physicians, we need to assure that payment models do not jeopardize the care we provide when we accept higher levels of personal financial risk. In this paper, we review the literature relevant to capitation, consider the interaction of financial incentives with physician and medical risk, and conclude that primary care physicians need to work to assure that capitated systems incorporate checks and balances which protect both patients and providers. We offer the following proposals for individuals and groups considering capitated contracts: (1) reimbursement for primary care physicians should recognize both individual patient encounters and the administrative work of patient care management; (2) reimbursement for subspecialists should recognize both access to subspecialty knowledge and expertise as well as patient care encounters, but in some situations, subspecialists may provide the majority of care to individual patients and will be reimbursed as primary care providers; (3) groups of physicians should accept financial risk for patient care only if they have the tools and resources to manage the care; (4) physicians sharing risk for patient care should meet regularly to discuss care and resource management; and (5) physicians must disclose the financial relationships they have with health plans and medical care organizations, and engage patients and communities in discussions about resource allocation. As a payment model, capitation offers opportunities for primary care physicians to influence the future of health care by improving the management of resources at a local level.

  5. Same-sex legal marriage and psychological well-being: findings from the California Health Interview Survey.

    PubMed

    Wight, Richard G; Leblanc, Allen J; Lee Badgett, M V

    2013-02-01

    We examined whether same-sex marriage was associated with nonspecific psychological distress among self-identified lesbian, gay, and bisexual adults, and whether it had the potential to offset mental health disparities between lesbian, gay, and bisexual persons and heterosexuals. Population-based data (weighted) were from the 2009 adult (aged 18-70 years) California Health Interview Survey. Within-group analysis of lesbian, gay, and bisexual persons included 1166 individuals (weighted proportion = 3.15%); within-group heterosexual analysis included 35 608 individuals (weighted proportion = 96.58%); and pooled analysis of lesbian, gay, and bisexual persons and heterosexuals included 36 774 individuals. Same-sex married lesbian, gay, and bisexual persons were significantly less distressed than lesbian, gay, and bisexual persons not in a legally recognized relationship; married heterosexuals were significantly less distressed than nonmarried heterosexuals. In adjusted pairwise comparisons, married heterosexuals had the lowest psychological distress, and lesbian, gay, and bisexual persons who were not in legalized relationships had the highest psychological distress (P < .001). Psychological distress was not significantly distinguishable among same-sex married lesbian, gay, and bisexual persons, lesbian, gay, and bisexual persons in registered domestic partnerships, and heterosexuals. Being in a legally recognized same-sex relationship, marriage in particular, appeared to diminish mental health differentials between heterosexuals and lesbian, gay, and bisexual persons. Researchers must continue to examine potential health benefits of same-sex marriage, which is at least in part a public health issue.

  6. Targeted Help for Spoken Dialogue Systems: Intelligent Feedback Improves Naive Users' Performance

    NASA Technical Reports Server (NTRS)

    Hockey, Beth Ann; Lemon, Oliver; Campana, Ellen; Hiatt, Laura; Aist, Gregory; Hieronymous, Jim; Gruenstein, Alexander; Dowding, John

    2003-01-01

    We present experimental evidence that providing naive users of a spoken dialogue system with immediate help messages related to their out-of-coverage utterances improves their success in using the system. A grammar-based recognizer and a Statistical Language Model (SLM) recognizer are run simultaneously. If the grammar-based recognizer suceeds, the less accurate SLM recognizer hypothesis is not used. When the grammar-based recognizer fails and the SLM recognizer produces a recognition hypothesis, this result is used by the Targeted Help agent to give the user feed-back on what was recognized, a diagnosis of what was problematic about the utterance, and a related in-coverage example. The in-coverage example is intended to encourage alignment between user inputs and the language model of the system. We report on controlled experiments on a spoken dialogue system for command and control of a simulated robotic helicopter.

  7. Genome-level determination of Plasmodium falciparum blood-stage targets of malarial clinical immunity in the Peruvian Amazon.

    PubMed

    Torres, Katherine J; Castrillon, Carlos E; Moss, Eli L; Saito, Mayuko; Tenorio, Roy; Molina, Douglas M; Davies, Huw; Neafsey, Daniel E; Felgner, Philip; Vinetz, Joseph M; Gamboa, Dionicia

    2015-04-15

    Persons with blood-stage Plasmodium falciparum parasitemia in the absence of symptoms are considered to be clinically immune. We hypothesized that asymptomatic subjects with P. falciparum parasitemia would differentially recognize a subset of P. falciparum proteins on a genomic scale. Compared with symptomatic subjects, sera from clinically immune, asymptomatically infected individuals differentially recognized 51 P. falciparum proteins, including the established vaccine candidate PfMSP1. Novel, hitherto unstudied hypothetical proteins and other proteins not previously recognized as potential vaccine candidates were also differentially recognized. Genes encoding the proteins differentially recognized by the Peruvian clinically immune individuals exhibited a significant enrichment of nonsynonymous nucleotide variation, an observation consistent with these genes undergoing immune selection. A limited set of P. falciparum protein antigens was associated with the development of naturally acquired clinical immunity in the low-transmission setting of the Peruvian Amazon. These results imply that, even in a low-transmission setting, an asexual blood-stage vaccine designed to reduce clinical malaria symptoms will likely need to contain large numbers of often-polymorphic proteins, a finding at odds with many current efforts in the design of vaccines against asexual blood-stage P. falciparum. © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  8. Teaching Business Students to Recognize a Firm in Distress: What Information Is Important to Experts?

    ERIC Educational Resources Information Center

    Lehmann, Constance M.; Norman, Carolyn Strand

    2005-01-01

    Business failures are the result of many decisions within individual companies--Can business students be taught to recognize a firm that is in financial distress? If it can be known and understood how professionals acquire expertise in evaluating the financial health of a firm, then it follows that structuring both the college classroom experience…

  9. Individual Differences in Incorrect Responding and the Ability to Discriminate the Source of the Products of Retrieval

    ERIC Educational Resources Information Center

    Jonker, Tanya R.

    2016-01-01

    When memory is tested, researchers are often interested in the items that were correctly recalled or recognized, while ignoring or factoring out trials where one "recalls" or "recognizes" a nonstudied item. However, intrusions and false alarms are more than nuisance data and can provide key insights into the memory system. The…

  10. Word-level recognition of multifont Arabic text using a feature vector matching approach

    NASA Astrophysics Data System (ADS)

    Erlandson, Erik J.; Trenkle, John M.; Vogt, Robert C., III

    1996-03-01

    Many text recognition systems recognize text imagery at the character level and assemble words from the recognized characters. An alternative approach is to recognize text imagery at the word level, without analyzing individual characters. This approach avoids the problem of individual character segmentation, and can overcome local errors in character recognition. A word-level recognition system for machine-printed Arabic text has been implemented. Arabic is a script language, and is therefore difficult to segment at the character level. Character segmentation has been avoided by recognizing text imagery of complete words. The Arabic recognition system computes a vector of image-morphological features on a query word image. This vector is matched against a precomputed database of vectors from a lexicon of Arabic words. Vectors from the database with the highest match score are returned as hypotheses for the unknown image. Several feature vectors may be stored for each word in the database. Database feature vectors generated using multiple fonts and noise models allow the system to be tuned to its input stream. Used in conjunction with database pruning techniques, this Arabic recognition system has obtained promising word recognition rates on low-quality multifont text imagery.

  11. Efficiency of printed materials in worksite health promotion.

    PubMed

    Kishchuk, N; Anbar, F; O'Loughlin, J; Masson, P; Sacks-Silver, G

    1991-01-01

    Printed health promotion materials are widely believed to be an efficient means of achieving basic health promotion objectives, such as increasing knowledge of risk factors. This study examined the efficiency of cardiovascular health promotion leaflets in reaching employees in a heterogeneous sample of worksites. Two types of distribution were used: copies of the leaflets were either made available centrally or distributed to each individual employee. Interviews were conducted with 272 employees in six worksites. Respondents were asked whether they recognized, had read, and had learned something from the leaflets. Only one-quarter of respondents recognized the leaflets and only 14% stated that they had learned something. The efficiency of the leaflets was therefore much lower than expected. Z-tests for proportions showed that recognition, reading, and learning were significantly greater among those employees who had been given individual copies of the material. Among those who had been given individual copies, 45% reported recognizing the leaflet, 36% reading it, and 23% learning something from it. Among those who had only central access, the respective scores were 11%, 7% and 6%. These results suggest that the potential cost-effectiveness of printed materials such as leaflets and brochures should be weighed against alternative forms of intervention, given specific program objectives and characteristics of the target population. They also suggest that the cost and effort required in organizing the distribution of individual copies may be recouped in greater penetration.

  12. Using Assistive Technology Outcomes Research to Inform Policy Related to the Employment of Individuals with Disabilities

    ERIC Educational Resources Information Center

    Mendelsohn, Steven; Edyburn, Dave L.; Rust, Kathy L.; Schwanke, Todd D.; Smith, Roger O.

    2008-01-01

    We know that work is recognized as a central component of life for individuals with and without disabilities. It yields many physical and psychological benefits to the individual while simultaneously contributing numerous benefits to society. Lawmakers have enacted a plethora of laws designed to prevent discrimination, provide incentives for…

  13. A tree classification for the selection forests of the Sierra Nevada

    Treesearch

    Duncan Dunning

    1928-01-01

    Individuality in man is accepted without question. In domestic animals, also, good and bad individuals are generally recognized. Even in some cultivated plants —orange trees and rubber trees— the poor producers are searched out and eliminated. Indeed, individual variability is a normal condition in all groups of organisms. Yet forest trees are...

  14. 31 CFR 357.31 - Certifying individuals.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Certifying individuals. 357.31 Section 357.31 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL... institutions, corporate central credit unions, and institutions that are members of Treasury-recognized...

  15. Career Resilience. ERIC Digest No. 178.

    ERIC Educational Resources Information Center

    Brown, Bettina Lankard

    Changes in the workplace such as mergers, acquisitions, reengineering, and downsizing are forcing individuals to recognize the temporary nature of all jobs and develop what has been termed "career resilience.""Career resilience" differs from "career self-reliance" in that the former refers to individual career…

  16. Multiple sclerosis: a geographical hypothesis.

    PubMed

    Carlyle, I P

    1997-12-01

    Multiple sclerosis remains a rare neurological disease of unknown aetiology, with a unique distribution, both geographically and historically. Rare in equatorial regions, it becomes increasingly common in higher latitudes; historically, it was first clinically recognized in the early nineteenth century. A hypothesis, based on geographical reasoning, is here proposed: that the disease is the result of a specific vitamin deficiency. Different individuals suffer the deficiency in separate and often unique ways. Evidence to support the hypothesis exists in cultural considerations, in the global distribution of the disease, and in its historical prevalence.

  17. Vision Research Literature May Not Represent the Full Intellectual Range of Autism Spectrum Disorder

    PubMed Central

    Brown, Alyse C.; Chouinard, Philippe A.; Crewther, Sheila G.

    2017-01-01

    Sensory, in particular visual processing is recognized as often perturbed in individuals with Autism Spectrum Disorder (ASD). However, in terms of the literature pertaining to visual processing, individuals in the normal intelligence range (IQ = 90–110) and above, are more frequently represented in study samples than individuals who score below normal in the borderline intellectual disability (ID) (IQ = 71–85) to ID (IQ < 70) ranges. This raises concerns as to whether or not current research is generalizable to a disorder that is often co-morbid with ID. Thus, the aim of this review is to better understand to what extent the current ASD visual processing literature is representative of the entire ASD population as either diagnosed or recognized under DSM-5. Our recalculation of ASD prevalence figures, using the criteria of DSM-5, indicates approximately 40% of the ASD population are likely to be ID although searching of the visual processing literature in ASD up to July 2016 showed that only 20% of papers included the ASD with-ID population. In the published literature, the mean IQ sampled was found to be 104, with about 80% of studies sampling from the 96–115 of the IQ range, highlighting the marked under-representation of the ID and borderline ID sections of the ASD population. We conclude that current understanding of visual processing and perception in ASD is not based on the mean IQ profile of the DSM-5 defined ASD population that now appears to lie within the borderline ID to ID range. Give the importance of the role of vision for the social and cognitive processing in ASD, we recommend accurately representing ASD via greater inclusion of individuals with IQ below 80, in future ASD research. PMID:28261072

  18. The assisted presentations of self in nursing home life.

    PubMed

    Næss, Anders; Fjær, Eivind Grip; Vabø, Mia

    2016-02-01

    In this paper, based on ethnographic data from five nursing homes, we introduce the concept of assisted self-presentation as an analytical tool for exploring how different care practices affect nursing home residents' dignity and sense of self. Practices of assisted self-presentation are geared at recognizing and preserving the individuality and autonomy of residents in situations where it may otherwise come under threat or be misrecognized. Sufficient or appropriate forms of attentiveness to residents' selves and sense of dignity is thus a matter of finding the right balance between intervening too much or too little in residents' production of their physical or social appearance. Here, staff-members' knowledge and recognition of the individuality of residents is essential. Whereas intervening too much in residents' appearance or performance of self might be perceived and experienced as pacifying, infantilizing, or as paternalistic overbearingness, intervening too little might be seen as neglectfulness or inhumane. Since practices of assisted self-presentation refer to a kind of social action, which will always be contingent upon the specific capacities and conditions of performing actors, it allows for the simultaneous recognition of failed or perverted work practices as well as promising practices through which residents' selves are successfully recognized. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. Individual Differences in Sleep Timing Relate to Melanopsin-Based Phototransduction in Healthy Adolescents and Young Adults

    PubMed Central

    van der Meijden, Wisse P.; Van Someren, Jamie L.; te Lindert, Bart H.W.; Bruijel, Jessica; van Oosterhout, Floor; Coppens, Joris E.; Kalsbeek, Andries; Cajochen, Christian; Bourgin, Patrice; Van Someren, Eus J.W.

    2016-01-01

    Study Objectives: Individual differences in sleep timing have been widely recognized and are of particular relevance in adolescents and young adults who often show mild to severely delayed sleep. The biological mechanisms underlying the between-subject variance remain to be determined. Recent human genetics studies showed an association between sleep timing and melanopsin gene variation, but support for functional effects on downstream pathways and behavior was not demonstrated before. We therefore investigated the association between the autonomic (i.e., pupil diameter) and behavioral (i.e., sleep timing) readouts of two different downstream brain areas, both affected by the same melanopsin-dependent retinal phototransduction: the olivary pretectal nucleus (OPN) and the suprachiasmatic nucleus (SCN). Methods: Our study population included 71 healthy individuals within an age range with known vulnerability to a delayed sleep phase (16.8–35.7 y, 37 males, 34 females). Pupillometry was performed to estimate functionality of the intrinsic melanopsin-signaling circuitry based on the OPN-mediated post-illumination pupil response (PIPR) to blue light. Sleep timing was quantified by estimating the SCN-mediated mid-sleep timing in three different ways in parallel: using a chronotype questionnaire, a sleep diary, and actigraphy. Results: All three measures consistently showed that those individuals with a later mid-sleep timing had a more pronounced PIPR (0.03 < P < 0.05), indicating a stronger blue-light responsiveness of the intrinsic melanopsin-based phototransduction circuitry. Conclusions: Trait-like individual differences in the melanopsin phototransduction circuitry contribute to individual differences in sleep timing. Blue light-sensitive young individuals are more prone to delayed sleep. Citation: van der Meijden WP, Van Someren JL; te Lindert BH, Bruijel J, van Oosterhout F, Coppens JE, Kalsbeek A, Cajochen C, Bourgin P, Van Someren EJ. Individual differences in sleep timing relate to melanopsin-based phototransduction in healthy adolescents and young adults. SLEEP 2016;39(6):1305–1310. PMID:27091519

  20. Understanding Collective Activities of People from Videos.

    PubMed

    Wongun Choi; Savarese, Silvio

    2014-06-01

    This paper presents a principled framework for analyzing collective activities at different levels of semantic granularity from videos. Our framework is capable of jointly tracking multiple individuals, recognizing activities performed by individuals in isolation (i.e., atomic activities such as walking or standing), recognizing the interactions between pairs of individuals (i.e., interaction activities) as well as understanding the activities of group of individuals (i.e., collective activities). A key property of our work is that it can coherently combine bottom-up information stemming from detections or fragments of tracks (or tracklets) with top-down evidence. Top-down evidence is provided by a newly proposed descriptor that captures the coherent behavior of groups of individuals in a spatial-temporal neighborhood of the sequence. Top-down evidence provides contextual information for establishing accurate associations between detections or tracklets across frames and, thus, for obtaining more robust tracking results. Bottom-up evidence percolates upwards so as to automatically infer collective activity labels. Experimental results on two challenging data sets demonstrate our theoretical claims and indicate that our model achieves enhances tracking results and the best collective classification results to date.

  1. Effects of team-based learning on perceived teamwork and academic performance in a health assessment subject.

    PubMed

    Park, Hyung-Ran; Kim, Chun-Ja; Park, Jee-Won; Park, Eunyoung

    2015-01-01

    The purpose of this study was to examine the effectiveness of team-based learning (a well-recognized learning and teaching strategy), applied in a health assessment subject, on nursing students' perceived teamwork (team-efficacy and team skills) and academic performance (individual and team readiness assurance tests, and examination scores). A prospective, one-group, pre- and post-test design enrolled a convenience sample of 74 second-year nursing students at a university in Suwon, Korea. Team-based learning was applied in a 2-credit health assessment subject over a 16-week semester. All students received written material one week before each class for readiness preparation. After administering individual- and team-readiness assurance tests consecutively, the subject instructor gave immediate feedback and delivered a mini-lecture to the students. Finally, students carried out skill based application exercises. The findings showed significant improvements in the mean scores of students' perceived teamwork after the introduction of team-based learning. In addition, team-efficacy was associated with team-adaptability skills and team-interpersonal skills. Regarding academic performance, team readiness assurance tests were significantly higher than individual readiness assurance tests over time. Individual readiness assurance tests were significantly related with examination scores, while team readiness assurance tests were correlated with team-efficacy and team-interpersonal skills. The application of team-based learning in a health assessment subject can enhance students' perceived teamwork and academic performance. This finding suggests that team-based learning may be an effective learning and teaching strategy for improving team-work of nursing students, who need to collaborate and effectively communicate with health care providers to improve patients' health.

  2. Feasibility study of an Integrated Program for Aerospace vehicle Design (IPAD). Volume 1A: Summary

    NASA Technical Reports Server (NTRS)

    Miller, R. E., Jr.; Redhed, D. D.; Kawaguchi, A. S.; Hansen, S. D.; Southall, J. W.

    1973-01-01

    IPAD was defined as a total system oriented to the product design process. This total system was designed to recognize the product design process, individuals and their design process tasks, and the computer-based IPAD System to aid product design. Principal elements of the IPAD System include the host computer and its interactive system software, new executive and data management software, and an open-ended IPAD library of technical programs to match the intended product design process. The basic goal of the IPAD total system is to increase the productivity of the product design organization. Increases in individual productivity were feasible through automation and computer support of routine information handling. Such proven automation can directly decrease cost and flowtime in the product design process.

  3. Treating frailty-a practical guide

    PubMed Central

    2011-01-01

    Frailty is a common syndrome that is associated with vulnerability to poor health outcomes. Frail older people have increased risk of morbidity, institutionalization and death, resulting in burden to individuals, their families, health care services and society. Assessment and treatment of the frail individual provide many challenges to clinicians working with older people. Despite frailty being increasingly recognized in the literature, there is a paucity of direct evidence to guide interventions to reduce frailty. In this paper we review methods for identification of frailty in the clinical setting, propose a model for assessment of the frail older person and summarize the current best evidence for treating the frail older person. We provide an evidence-based framework that can be used to guide the diagnosis, assessment and treatment of frail older people. PMID:21733149

  4. Responsibility and age-related dementia.

    PubMed

    Frantik, Petr

    2018-05-01

    This article identifies the assumption of responsibility as a basic need of human beings and applies the concept specifically to older people with dementia or Alzheimer's disease. It suggests a two-level concept of responsibility, based on the approach of discourse ethicist Karl-Otto Apel, as a promising approach to recognizing human diversity while at the same time respecting people's equal rights to participate in discourse. This concept can serve as a theoretical starting point for the construction of individually adapted types of responsibility. Furthermore, the article describes practical ideas (primarily the practice of doll therapy) that can enable people with dementia or Alzheimer's disease to assume responsibility. Direct communication and a reflective, sensitive consideration of each individual case are identified as important prerequisites for the inclusion of elderly people with dementia. © 2018 John Wiley & Sons Ltd.

  5. Intimate partner violence prevention program in an Asian immigrant community: integrating theories, data, and community.

    PubMed

    Yoshihama, Mieko; Ramakrishnan, Aparna; Hammock, Amy C; Khaliq, Mahmooda

    2012-07-01

    To fill an existing gap in research and practice on intimate partner violence (IPV) in immigrant communities, the authors developed an IPV prevention program, called the Shanti Project, in an Asian Indian community in the Midwest. Building on the notion of shanti (harmony/peace), a cherished value and strength of the community, we created a communications campaign that combined social marketing and community-based participatory approaches. Recognizing the interactive influences of multiple levels of social ecology, campaign activities were designed to bring about changes at the individual, relationship/family, organization, and community levels. This article presents the development of this theoretically, empirically, and community-based IPV prevention program.

  6. Recognizing "me" benefits "we": Investigating the positive spillover effects of formal individual recognition in teams.

    PubMed

    Li, Ning; Zheng, Xiaoming; Harris, T Brad; Liu, Xin; Kirkman, Bradley L

    2016-07-01

    Many organizations use formal recognition programs (e.g., "employee of the month") as a way to publically acknowledge an individual employee's outstanding performance and motivate continued high performance. However, it remains unclear whether emphasizing individual achievement in a team context is beneficial or detrimental for recipients' teammates and, by extension, the team as a whole. Drawing on a social influence perspective, we examine potential spillover effects of individual formal recognition programs in teams. We hypothesize that a single team member's recognition will produce positive spillover effects on other team members' performance, as well as overall team performance, via social influence processes, especially when the award recipient is located in a central position in a team. Findings from 2 lab experiments of 24 teams and 40 teams (Study 1 and Study 2, respectively) and a field experiment of 52 manufacturing teams (Study 3) reveal that formally recognizing a team member leads to positive changes in her/his teammates' individual and collective performance. Thus, formal social recognition programs can potentially provide a motivational effect beyond individual recipients. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  7. Mind the gap: glucocorticoids modulate hippocampal glutamate tone underlying individual differences in stress susceptibility.

    PubMed

    Nasca, C; Bigio, B; Zelli, D; Nicoletti, F; McEwen, B S

    2015-06-01

    Why do some individuals succumb to stress and develop debilitating psychiatric disorders, whereas others adapt well in the face of adversity? There is a gap in understanding the neural bases of individual differences in the responses to environmental factors on brain development and functions. Here, using a novel approach for screening an inbred population of laboratory animals, we identified two subpopulations of mice: susceptible mice that show mood-related abnormalities compared with resilient mice, which cope better with stress. This approach combined with molecular and behavioral analyses, led us to recognize, in hippocampus, presynaptic mGlu2 receptors, which inhibit glutamate release, as a stress-sensitive marker of individual differences to stress-induced mood disorders. Indeed, genetic mGlu2 deletion in mice results in a more severe susceptibility to stress, mimicking the susceptible mouse sub-population. Furthermore, we describe an underlying mechanism by which glucocorticoids, acting via mineralocorticoid receptors (MRs), decrease resilience to stress via downregulation of mGlu2 receptors. We also provide a mechanistic link between MRs and an epigenetic control of the glutamatergic synapse that underlies susceptibility to stressful experiences. The approach and the epigenetic allostasis concept introduced here serve as a model for identifying individual differences based upon biomarkers and underlying mechanisms and also provide molecular features that may be useful in translation to human behavior and psychopathology.

  8. Newly recognized recessive syndrome characterized by dysmorphic features, hypogonadotropic hypogonadism, severe microcephaly, and sensorineural hearing loss maps to 3p21.3.

    PubMed

    Jenkinson, Emma M; Kingston, Helen; Urquhart, Jill; Khan, Naz; Melville, Athalie; Swinton, Martin; Crow, Yanick J; Davis, Julian R E; Trump, Dorothy; Newman, William G

    2011-12-01

    We present a newly recognized, likely autosomal recessive, pleiotropic disorder seen in four individuals (three siblings and their nephew) from a consanguineous family of Pakistani origin. The condition is characterized by hypogonadotropic hypogonadism, severe microcephaly, sensorineural deafness, moderate learning disability, and distinctive facial dysmorphic features. Autozygosity mapping using SNP array genotyping defined a single, large autozygous region of 13.1 Mb on chromosome 3p21 common to the affected individuals. The critical region contains 227 genes and initial sequence analysis of a functional candidate gene has not identified causative mutations. Copyright © 2011 Wiley Periodicals, Inc.

  9. Resources to cope with stigma related to HIV status, gender identity, and sexual orientation in gay men and transgender women.

    PubMed

    Arístegui, Inés; Radusky, Pablo D; Zalazar, Virginia; Lucas, Mar; Sued, Omar

    2018-02-01

    The stigma related to HIV status, gender identity, and sexual orientation has negative implications for the quality of life of individuals. A qualitative study was conducted to explore the resources that these stigmatized groups recognize as tools to cope with stigma and maintain their psychological well-being. Four focus groups were conducted with gay men and transgender women divided by HIV status. A thematic analysis revealed that individual, interpersonal, and institutional resources are commonly recognized as coping resources. This article discusses the importance of enhancing self-acceptance, social support, and a legal framework that legitimizes these groups as right holders.

  10. Facial emotion recognition deficits following moderate-severe Traumatic Brain Injury (TBI): re-examining the valence effect and the role of emotion intensity.

    PubMed

    Rosenberg, Hannah; McDonald, Skye; Dethier, Marie; Kessels, Roy P C; Westbrook, R Frederick

    2014-11-01

    Many individuals who sustain moderate-severe traumatic brain injuries (TBI) are poor at recognizing emotional expressions, with a greater impairment in recognizing negative (e.g., fear, disgust, sadness, and anger) than positive emotions (e.g., happiness and surprise). It has been questioned whether this "valence effect" might be an artifact of the wide use of static facial emotion stimuli (usually full-blown expressions) which differ in difficulty rather than a real consequence of brain impairment. This study aimed to investigate the valence effect in TBI, while examining emotion recognition across different intensities (low, medium, and high). Twenty-seven individuals with TBI and 28 matched control participants were tested on the Emotion Recognition Task (ERT). The TBI group was more impaired in overall emotion recognition, and less accurate recognizing negative emotions. However, examining the performance across the different intensities indicated that this difference was driven by some emotions (e.g., happiness) being much easier to recognize than others (e.g., fear and surprise). Our findings indicate that individuals with TBI have an overall deficit in facial emotion recognition, and that both people with TBI and control participants found some emotions more difficult than others. These results suggest that conventional measures of facial affect recognition that do not examine variance in the difficulty of emotions may produce erroneous conclusions about differential impairment. They also cast doubt on the notion that dissociable neural pathways underlie the recognition of positive and negative emotions, which are differentially affected by TBI and potentially other neurological or psychiatric disorders.

  11. An Exploration of Leader Conceptual Capability.

    ERIC Educational Resources Information Center

    Lewis, Philip

    Leadership researchers and theorists alike have come to recognize that the critical tasks of senior level leaders are quite different from the critical leadership tasks of individuals occupying lower level leadership positions. Departing from the bulk of prior research on individual differences in leadership effectiveness which focused on…

  12. Toward a Theory of Personal Politics

    ERIC Educational Resources Information Center

    Fritsch, Jocelyn

    2010-01-01

    The ability to effectively navigate organizational politics to achieve one's goals has long been recognized as necessary for individuals to experience success within their organizations. Many studies have linked the effective use of political behaviors to increased individual performance. As such, many scholars within HRD and other disciplines…

  13. Survey of cognitive rehabilitation practices in the state of Kuwait.

    PubMed

    Manee, Fahad S; Nadar, Mohammed Sh; Jassem, Zainab; Chavan, Shashidhar Rao

    2017-03-01

    Background Rehabilitation professionals must be astute at recognizing, assessing, and treating individuals with cognitive deficits. No research is available to examine cognitive rehabilitation practices applied to individuals with neurological conditions in Kuwait. To identify the use of cognitive assessments, the availability of resources, and the barriers to cognitive rehabilitation practices in Kuwait. Methods Face-to-face interviews were conducted with health care professionals working with adult individuals with neurological conditions. These professionals included occupational therapists, speech-language pathologists, psychiatrists, and neurologists. Results The most commonly used cognitive based assessments are MMSE (41%), and MoCA and LOTCA (15.2%). The only clinical assessment used is the Line-Bisection Test (2.2%). The most used occupation-based assessments are FIM (6.5%), COPM (4.3%), the Interest Checklist (2.2%), and the Barthel Index (2.2%). Resources related to cognitive rehabilitation in Kuwait that are unavailable to practitioners include journal clubs (91%), special interest groups (89%), and continuing education programmes (82.6%). Barriers to cognitive rehabilitation practice included lack of sufficient funds for continuing education, lack of time, lack of standardized assessments, and lack of inter-professional teamwork. Conclusion Many adults in Kuwait live with cognitive impairment. There is a need to develop appropriate evidence-based cognitive rehabilitation clinical guidelines in Kuwait.

  14. A tool for classifying individuals with chronic back pain: using multivariate pattern analysis with functional magnetic resonance imaging data.

    PubMed

    Callan, Daniel; Mills, Lloyd; Nott, Connie; England, Robert; England, Shaun

    2014-01-01

    Chronic pain is one of the most prevalent health problems in the world today, yet neurological markers, critical to diagnosis of chronic pain, are still largely unknown. The ability to objectively identify individuals with chronic pain using functional magnetic resonance imaging (fMRI) data is important for the advancement of diagnosis, treatment, and theoretical knowledge of brain processes associated with chronic pain. The purpose of our research is to investigate specific neurological markers that could be used to diagnose individuals experiencing chronic pain by using multivariate pattern analysis with fMRI data. We hypothesize that individuals with chronic pain have different patterns of brain activity in response to induced pain. This pattern can be used to classify the presence or absence of chronic pain. The fMRI experiment consisted of alternating 14 seconds of painful electric stimulation (applied to the lower back) with 14 seconds of rest. We analyzed contrast fMRI images in stimulation versus rest in pain-related brain regions to distinguish between the groups of participants: 1) chronic pain and 2) normal controls. We employed supervised machine learning techniques, specifically sparse logistic regression, to train a classifier based on these contrast images using a leave-one-out cross-validation procedure. We correctly classified 92.3% of the chronic pain group (N = 13) and 92.3% of the normal control group (N = 13) by recognizing multivariate patterns of activity in the somatosensory and inferior parietal cortex. This technique demonstrates that differences in the pattern of brain activity to induced pain can be used as a neurological marker to distinguish between individuals with and without chronic pain. Medical, legal and business professionals have recognized the importance of this research topic and of developing objective measures of chronic pain. This method of data analysis was very successful in correctly classifying each of the two groups.

  15. A Tool for Classifying Individuals with Chronic Back Pain: Using Multivariate Pattern Analysis with Functional Magnetic Resonance Imaging Data

    PubMed Central

    Callan, Daniel; Mills, Lloyd; Nott, Connie; England, Robert; England, Shaun

    2014-01-01

    Chronic pain is one of the most prevalent health problems in the world today, yet neurological markers, critical to diagnosis of chronic pain, are still largely unknown. The ability to objectively identify individuals with chronic pain using functional magnetic resonance imaging (fMRI) data is important for the advancement of diagnosis, treatment, and theoretical knowledge of brain processes associated with chronic pain. The purpose of our research is to investigate specific neurological markers that could be used to diagnose individuals experiencing chronic pain by using multivariate pattern analysis with fMRI data. We hypothesize that individuals with chronic pain have different patterns of brain activity in response to induced pain. This pattern can be used to classify the presence or absence of chronic pain. The fMRI experiment consisted of alternating 14 seconds of painful electric stimulation (applied to the lower back) with 14 seconds of rest. We analyzed contrast fMRI images in stimulation versus rest in pain-related brain regions to distinguish between the groups of participants: 1) chronic pain and 2) normal controls. We employed supervised machine learning techniques, specifically sparse logistic regression, to train a classifier based on these contrast images using a leave-one-out cross-validation procedure. We correctly classified 92.3% of the chronic pain group (N = 13) and 92.3% of the normal control group (N = 13) by recognizing multivariate patterns of activity in the somatosensory and inferior parietal cortex. This technique demonstrates that differences in the pattern of brain activity to induced pain can be used as a neurological marker to distinguish between individuals with and without chronic pain. Medical, legal and business professionals have recognized the importance of this research topic and of developing objective measures of chronic pain. This method of data analysis was very successful in correctly classifying each of the two groups. PMID:24905072

  16. "Measuring up" to ethical standards in service delivery to college students on the Autism Spectrum: A practical application of Powell's model for ethical practices in clinical phonetics and linguistics.

    PubMed

    Weiss, Amy L; Rohland, Pamela

    2014-01-01

    This paper examined an interdisciplinary college-based support programme, the Communication Coaching Program (CCP), designed for students diagnosed on the autism spectrum in light of six ethical constructs described by Powell. Collecting data to monitor the successes and ongoing needs of individual participants in the programme is of vital importance, of course, but only addresses a portion of the efficacy question. In addition, the authors, who co-direct the programme and represent different professional expertise and perspectives, recognize the importance of determining whether their evolving intervention model has also been successful in meeting the ethical standards of their respective professions. Careful review of the 4 years of the CCP's operation in terms of ethical constructs has yielded evidence that the CCP, although based on sound principles of theory and scholarship, should be further individualized to meet the particular needs of participants diagnosed with deficits in social communication and executive functioning skills.

  17. An Emerging Role for Polystores in Precision Medicine

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Begoli, Edmon; Christian, J. Blair; Gadepally, Vijay

    Medical data is organically heterogeneous, and it usually varies significantly in both size and composition. Yet, this data is also a key for the recent and promising field of precision medicine, which focuses on identifying and tailoring appropriate medical treatments for the needs of the individual patients, based on their specific conditions, their medical history, lifestyle, genetic, and other individual factors. As we, and a database community at large, recognize that a “one size does not fit all” solution is required to work with such data, we present in this paper our observations based on our experiences, and the applicationsmore » in the field of precision medicine. Finally, we make the case for the use of polystore architecture; how it applies for precision medicine; we discuss the reference architecture; describe some of its critical components (array database); and discuss the specific types of analysis that directly benefit from this database architecture, and the ways it serves the data.« less

  18. The Impossibility of Criminal Justice Ethics: Toward a Phenomenology of the Possible.

    PubMed

    Polizzi, David

    2018-06-01

    Regardless the specific theoretical perspective, all ethical formulations for criminal justice practice in some way construct the ontological character of the offender, which, in turn, situates both epistemology and method. How this ethical process ultimately constructs the offender will likely help to establish the degree of ethical worth such an individual is deemed worthy to receive. Whether based upon the seriousness of the crime or based upon the specific configuration of the architecture of incarceration, the very possibility of legitimate ethical practice is greatly compromised. Such results can be better avoided when the ethical import of the individual is ontologically situated within the very definition of what it means to be human. 1 By situating this discussion within the context of the analytic psychology of Carl Jung and his concept of the shadow and the originary ethics of Martin Heidegger found in Being and Time, a more ontologically configured possibility for a criminal justice ethics can be recognized.

  19. Octopuses (Enteroctopus dofleini) recognize individual humans.

    PubMed

    Anderson, Roland C; Mather, Jennifer A; Monette, Mathieu Q; Zimsen, Stephanie R M

    2010-01-01

    This study exposed 8 Enteroctopus dofleini separately to 2 unfamiliar individual humans over a 2-week period under differing circumstances. One person consistently fed the octopuses and the other touched them with a bristly stick. Each human recorded octopus body patterns, behaviors, and respiration rates directly after each treatment. At the end of 2 weeks, a body pattern (a dark Eyebar) and 2 behaviors (reaching arms toward or away from the tester and funnel direction) were significantly different in response to the 2 humans. The respiration rate of the 4 larger octopuses changed significantly in response to the 2 treatments; however, there was no significant difference in the 4 smaller octopuses' respiration. Octopuses' ability to recognize humans enlarges our knowledge of the perceptual ability of this nonhuman animal, which depends heavily on learning in response to visual information. Any training paradigm should take such individual recognition into consideration as it could significantly alter the octopuses' responses.

  20. Survivors Remorse: antibody-mediated protection against HIV-1.

    PubMed

    Lewis, George K; Pazgier, Marzena; DeVico, Anthony L

    2017-01-01

    It is clear that antibodies can play a pivotal role in preventing the transmission of HIV-1 and large efforts to identify an effective antibody-based vaccine to quell the epidemic. Shortly after HIV-1 was discovered as the cause of AIDS, the search for epitopes recognized by neutralizing antibodies became the driving strategy for an antibody-based vaccine. Neutralization escape variants were discovered shortly thereafter, and, after almost three decades of investigation, it is now known that autologous neutralizing antibody responses and their selection of neutralization resistant HIV-1 variants can lead to broadly neutralizing antibodies in some infected individuals. This observation drives an intensive effort to identify a vaccine to elicit broadly neutralizing antibodies. In contrast, there has been less systematic study of antibody specificities that must rely mainly or exclusively on other protective mechanisms, although non-human primate (NHP) studies as well as the RV144 vaccine trial indicate that non-neutralizing antibodies can contribute to protection. Here we propose a novel strategy to identify new epitope targets recognized by these antibodies for which viral escape is unlikely or impossible. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  1. A simple rule reduces costs of extragroup parasitism in a communally breeding bird.

    PubMed

    Riehl, Christina

    2010-10-26

    How do cooperatively breeding groups resist invasion by parasitic "cheaters," which dump their eggs in the communal nest but provide no parental care [1,2]? Here I show that Greater Anis (Crotophaga major), Neotropical cuckoos that nest in social groups containing several breeding females [3], use a simple rule based on the timing of laying to recognize and reject eggs laid by extragroup parasites. I experimentally confirmed that Greater Anis cannot recognize parasitic eggs based on the appearance of host egg phenotypes or on the number of eggs in the clutch. However, they can discriminate between freshly laid eggs and those that have already been incubated, and they accordingly eject asynchronous eggs. This mechanism is reliable in naturally parasitized nests, because group members typically lay their eggs in tight synchrony, whereas the majority of parasitic eggs are laid several days later. Rejection of asynchronous eggs therefore provides a rare empirical example of a complex, group-level behavior that arises through relatively simple "rules of thumb" without requiring advanced cognitive mechanisms such as learning, counting, or individual recognition. Copyright © 2010 Elsevier Ltd. All rights reserved.

  2. Comprehensive tire-road friction coefficient estimation based on signal fusion method under complex maneuvering operations

    NASA Astrophysics Data System (ADS)

    Li, L.; Yang, K.; Jia, G.; Ran, X.; Song, J.; Han, Z.-Q.

    2015-05-01

    The accurate estimation of the tire-road friction coefficient plays a significant role in the vehicle dynamics control. The estimation method should be timely and reliable for the controlling requirements, which means the contact friction characteristics between the tire and the road should be recognized before the interference to ensure the safety of the driver and passengers from drifting and losing control. In addition, the estimation method should be stable and feasible for complex maneuvering operations to guarantee the control performance as well. A signal fusion method combining the available signals to estimate the road friction is suggested in this paper on the basis of the estimated ones of braking, driving and steering conditions individually. Through the input characteristics and the states of the vehicle and tires from sensors the maneuvering condition may be recognized, by which the certainty factors of the friction of the three conditions mentioned above may be obtained correspondingly, and then the comprehensive road friction may be calculated. Experimental vehicle tests validate the effectiveness of the proposed method through complex maneuvering operations; the estimated road friction coefficient based on the signal fusion method is relatively timely and accurate to satisfy the control demands.

  3. Robust representations of individual faces in chimpanzees (Pan troglodytes) but not monkeys (Macaca mulatta).

    PubMed

    Taubert, Jessica; Weldon, Kimberly B; Parr, Lisa A

    2017-03-01

    Being able to recognize the faces of our friends and family members no matter where we see them represents a substantial challenge for the visual system because the retinal image of a face can be degraded by both changes in the person (age, expression, pose, hairstyle, etc.) and changes in the viewing conditions (direction and degree of illumination). Yet most of us are able to recognize familiar people effortlessly. A popular theory for how face recognition is achieved has argued that the brain stabilizes facial appearance by building average representations that enhance diagnostic features that reliably vary between people while diluting features that vary between instances of the same person. This explains why people find it easier to recognize average images of people, created by averaging multiple images of the same person together, than single instances (i.e. photographs). Although this theory is gathering momentum in the psychological and computer sciences, there is no evidence of whether this mechanism represents a unique specialization for individual recognition in humans. Here we tested two species, chimpanzees (Pan troglodytes) and rhesus monkeys (Macaca mulatta), to determine whether average images of different familiar individuals were easier to discriminate than photographs of familiar individuals. Using a two-alternative forced-choice, match-to-sample procedure, we report a behaviour response profile that suggests chimpanzees encode the faces of conspecifics differently than rhesus monkeys and in a manner similar to humans.

  4. Differential Recognition of Mycobacterium tuberculosis-Specific Epitopes as a Function of Tuberculosis Disease History.

    PubMed

    Scriba, Thomas J; Carpenter, Chelsea; Pro, Sebastian Carrasco; Sidney, John; Musvosvi, Munyaradzi; Rozot, Virginie; Seumois, Grégory; Rosales, Sandy L; Vijayanand, Pandurangan; Goletti, Delia; Makgotlho, Edward; Hanekom, Willem; Hatherill, Mark; Peters, Bjoern; Sette, Alessandro; Arlehamn, Cecilia S Lindestam

    2017-09-15

    Individuals with a history of tuberculosis (TB) disease are at elevated risk of disease recurrence. The underlying cause is not known, but one explanation is that previous disease results in less-effective immunity against Mycobacterium tuberculosis (Mtb). We hypothesized that the repertoire of Mtb-derived epitopes recognized by T cells from individuals with latent Mtb infection differs as a function of previous diagnosis of active TB disease. T-cell responses to peptide pools in samples collected from an adult screening and an adolescent validation cohort were measured by IFN-γ enzyme-linked immunospot assay or intracellular cytokine staining. We identified a set of "type 2" T-cell epitopes that were recognized at 10-fold-lower levels in Mtb-infected individuals with a history of TB disease less than 6 years ago than in those without previous TB. By contrast, "type 1" epitopes were recognized equally well in individuals with or without previous TB. The differential epitope recognition was not due to differences in HLA class II binding, memory phenotypes, or gene expression in the responding T cells. Instead, "TB disease history-sensitive" type 2 epitopes were significantly (P < 0.0001) more homologous to sequences from bacteria found in the human microbiome than type 1 epitopes. Preferential loss of T-cell reactivity to Mtb epitopes that are homologous to bacteria in the microbiome in persons with previous TB disease may reflect long-term effects of antibiotic TB treatment on the microbiome.

  5. Does increasing the intelligibility of a competing sound source interfere more with speech comprehension in older adults than it does in younger adults?

    PubMed

    Lu, Zihui; Daneman, Meredyth; Schneider, Bruce A

    2016-11-01

    A previous study (Schneider, Daneman, Murphy, & Kwong See, 2000) found that older listeners' decreased ability to recognize individual words in a noisy auditory background was responsible for most, if not all, of the comprehension difficulties older adults experience when listening to a lecture in a background of unintelligible babble. The present study investigated whether the use of a more intelligible distracter (a competing lecture) might reveal an increased susceptibility to distraction in older adults. The results from Experiments 1 and 2 showed that both normal-hearing and hearing-impaired older adults performed poorer than younger adults when everyone was tested in identical listening situations. However, when the listening situation was individually adjusted to compensate for age-related differences in the ability to recognize individual words in noise, age-related difference in comprehension disappeared. Experiment 3 compared the masking effects of a single-talker competing lecture to a babble of 12 voices directly after adjusting for word recognition. The results showed that the competing lecture interfered more than did the babble for both younger and older listeners. Interestingly, an increase in the level of noise had a deleterious effect on listening when the distractor was babble but had no effect when it was a competing lecture. These findings indicated that the speech comprehension difficulties of healthy older adults in noisy backgrounds primarily reflect age-related declines in the ability to recognize individual words.

  6. Functional architecture of visual emotion recognition ability: A latent variable approach.

    PubMed

    Lewis, Gary J; Lefevre, Carmen E; Young, Andrew W

    2016-05-01

    Emotion recognition has been a focus of considerable attention for several decades. However, despite this interest, the underlying structure of individual differences in emotion recognition ability has been largely overlooked and thus is poorly understood. For example, limited knowledge exists concerning whether recognition ability for one emotion (e.g., disgust) generalizes to other emotions (e.g., anger, fear). Furthermore, it is unclear whether emotion recognition ability generalizes across modalities, such that those who are good at recognizing emotions from the face, for example, are also good at identifying emotions from nonfacial cues (such as cues conveyed via the body). The primary goal of the current set of studies was to address these questions through establishing the structure of individual differences in visual emotion recognition ability. In three independent samples (Study 1: n = 640; Study 2: n = 389; Study 3: n = 303), we observed that the ability to recognize visually presented emotions is based on different sources of variation: a supramodal emotion-general factor, supramodal emotion-specific factors, and face- and within-modality emotion-specific factors. In addition, we found evidence that general intelligence and alexithymia were associated with supramodal emotion recognition ability. Autism-like traits, empathic concern, and alexithymia were independently associated with face-specific emotion recognition ability. These results (a) provide a platform for further individual differences research on emotion recognition ability, (b) indicate that differentiating levels within the architecture of emotion recognition ability is of high importance, and (c) show that the capacity to understand expressions of emotion in others is linked to broader affective and cognitive processes. (c) 2016 APA, all rights reserved).

  7. Digital Badges for Staff Training: Motivate Employees to Learn with Micro-Credentials

    ERIC Educational Resources Information Center

    Copenhaver, Kimberly; Pritchard, Liz

    2017-01-01

    Integrating micro-credentialing into employee training programs offers libraries an innovative and individualized way to recognize and certify learning and achievement. Digital badges provide a low-cost initiative to support learning benefiting both the individual and institution, offering evidence of skill development that transcends the library…

  8. Humoral immune profiling of mycobacterial antigen recognition in sarcoidosis and Löfgren's syndrome using high-content peptide microarrays.

    PubMed

    Ferrara, Giovanni; Valentini, Davide; Rao, Martin; Wahlström, Jan; Grunewald, Johan; Larsson, Lars-Olof; Brighenti, Susanna; Dodoo, Ernest; Zumla, Alimuddin; Maeurer, Markus

    2017-03-01

    Sarcoidosis is considered an idiopathic granulomatous disease, although similar immunological and clinical features with tuberculosis (TB) suggest mycobacterial involvement in its pathogenesis. High-content peptide microarrays (HCPM) may help to decipher mycobacteria-specific antibody reactivity in sarcoidosis. Serum samples from patients with sarcoidosis, Löfgren's syndrome, and TB, as well as from healthy individuals (12/group), were tested on HCPM containing 5964 individual peptides spanning 154 Mycobacterium tuberculosis proteins displayed as 15-amino acid stretches. Inclusion/exclusion and significance analyses were performed according to published methods. Each study group recognized 68-78% M. tuberculosis peptides at least once. M. tuberculosis epitope recognition by sarcoidosis patient sera was 42.7%, and by TB patient sera was 39.1%. Seven and 16 peptides were recognized in 9/12 (75%) and 8/12 (67%) sarcoidosis patient sera but not in TB patient sera, respectively. Nine (75%) and eight (67%) out of twelve TB patient sera, respectively recognized M. tuberculosis peptides that were not recognized in sarcoidosis patient sera. Specific IgG recognition patterns for M. tuberculosis antigens in sarcoidosis patients re-affirm mycobacterial involvement in sarcoidosis, providing biologically relevant targets for future studies pertaining to diagnostics and immunotherapy. Copyright © 2017. Published by Elsevier Ltd.

  9. Designing payments for ecosystem services: Lessons from previous experience with incentive-based mechanisms

    PubMed Central

    Jack, B. Kelsey; Kousky, Carolyn; Sims, Katharine R. E.

    2008-01-01

    Payments for ecosystem services (PES) policies compensate individuals or communities for undertaking actions that increase the provision of ecosystem services such as water purification, flood mitigation, or carbon sequestration. PES schemes rely on incentives to induce behavioral change and can thus be considered part of the broader class of incentive- or market-based mechanisms for environmental policy. By recognizing that PES programs are incentive-based, policymakers can draw on insights from the substantial body of accumulated knowledge about this class of instruments. In particular, this article offers a set of lessons about how the environmental, socioeconomic, political, and dynamic context of a PES policy is likely to interact with policy design to produce policy outcomes, including environmental effectiveness, cost-effectiveness, and poverty alleviation. PMID:18621696

  10. Designing payments for ecosystem services: Lessons from previous experience with incentive-based mechanisms.

    PubMed

    Jack, B Kelsey; Kousky, Carolyn; Sims, Katharine R E

    2008-07-15

    Payments for ecosystem services (PES) policies compensate individuals or communities for undertaking actions that increase the provision of ecosystem services such as water purification, flood mitigation, or carbon sequestration. PES schemes rely on incentives to induce behavioral change and can thus be considered part of the broader class of incentive- or market-based mechanisms for environmental policy. By recognizing that PES programs are incentive-based, policymakers can draw on insights from the substantial body of accumulated knowledge about this class of instruments. In particular, this article offers a set of lessons about how the environmental, socioeconomic, political, and dynamic context of a PES policy is likely to interact with policy design to produce policy outcomes, including environmental effectiveness, cost-effectiveness, and poverty alleviation.

  11. The power gap: freedom, power and mental illness.

    PubMed

    Kelly, Brendan D

    2006-10-01

    Up to one in four individuals in the US meet the diagnostic criteria for a mental illness in any given year and a significant proportion have severe or recurring illnesses (e.g. schizophrenia). Despite this prevalence, mental health services remain poorly funded, mental illness remains misunderstood and individuals with recurring illness are constrained to live lives characterized by isolation, under-employment, stigma and denial of rights. Here I examine the idea that this situation is attributable, at least in part, to the ways in which the freedom and power of the mentally ill are undermined by a range of factors, including: (i) dispersion of political power amongst interest groups, which, combined with the relatively wide distribution of the 'interest' of mental illness, has the paradoxical result that mental health interest groups do not command political power proportional to the number affected; (ii) systematic exclusion of the mentally ill from full participation in civic, social and political life (structural violence), resulting in a lack of emphasis on mental health on political agendas and the exclusion of certain policy options as possible responses and (iii) difficulties the mentally ill may experience recognizing or articulating their own needs the absence of effective health-care systems, and the absence of knowledge about alternative systems. I argue that the enhancement of individual agency is central to efforts to address this power gap, including: (i) rights-based approaches, involving the enhancement of national mental health legislation, improvement of advocacy, empowerment and guardianship processes and development of governance, accountability and quality procedures in mental health services; (ii) approaches based on enhancing direct political participation, including voter-registration programmes and development of larger, more effective interest groups and (iii) additional approaches, including increasing accountability throughout services, recognizing the effects of socio-political change on the context of care and adapting the concept of 'soft power' to strengthen advocacy programmes.

  12. The sequential structure of brain activation predicts skill.

    PubMed

    Anderson, John R; Bothell, Daniel; Fincham, Jon M; Moon, Jungaa

    2016-01-29

    In an fMRI study, participants were trained to play a complex video game. They were scanned early and then again after substantial practice. While better players showed greater activation in one region (right dorsal striatum) their relative skill was better diagnosed by considering the sequential structure of whole brain activation. Using a cognitive model that played this game, we extracted a characterization of the mental states that are involved in playing a game and the statistical structure of the transitions among these states. There was a strong correspondence between this measure of sequential structure and the skill of different players. Using multi-voxel pattern analysis, it was possible to recognize, with relatively high accuracy, the cognitive states participants were in during particular scans. We used the sequential structure of these activation-recognized states to predict the skill of individual players. These findings indicate that important features about information-processing strategies can be identified from a model-based analysis of the sequential structure of brain activation. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. MHC class-I associated phosphopeptides are the targets of memory-like immunity in leukemia

    PubMed Central

    Cobbold, Mark; De La Peña, Hugo; Norris, Andrew; Polefrone, Joy; Qian, Jie; English, A. Michelle; Cummings, Kara; Penny, Sarah; Turner, James E.; Cottine, Jennifer; Abelin, Jennifer G; Malaker, Stacy A; Zarling, Angela L; Huang, Hsing-Wen; Goodyear, Oliver; Freeman, Sylvie; Shabanowitz, Jeffrey; Pratt, Guy; Craddock, Charles; Williams, Michael E; Hunt, Donald F; Engelhard, Victor H

    2014-01-01

    Deregulation of signaling pathways involving phosphorylation is a hallmark of malignant transformation. Degradation of phosphoproteins generates cancer-specific phosphopeptides that are associated with MHC-I and II molecules and recognized by T-cells. We identified 95 phosphopeptides presented on the surface of primary hematological tumors and normal tissues, including 61 that were tumor-specific. Phosphopeptides were more prevalent on more aggressive and malignant samples. CD8 T-cell lines specific for these phosphopeptides recognized and killed both leukemia cell lines and HLA-matched primary leukemia cells ex vivo. Healthy individuals showed surprisingly high levels of CD8 T-cell responses against many of these phosphopeptides within the circulating memory compartment. This immunity was significantly reduced or absent in some leukemia patients, which correlated with clinical outcome, and was restored following allogeneic stem cell transplantation. These results suggest that phosphopeptides may be targets of cancer immune surveillance in humans, and point to their importance for development of vaccine-based and T-cell adoptive transfer immunotherapies.. PMID:24048523

  14. Robots Learn to Recognize Individuals from Imitative Encounters with People and Avatars

    NASA Astrophysics Data System (ADS)

    Boucenna, Sofiane; Cohen, David; Meltzoff, Andrew N.; Gaussier, Philippe; Chetouani, Mohamed

    2016-02-01

    Prior to language, human infants are prolific imitators. Developmental science grounds infant imitation in the neural coding of actions, and highlights the use of imitation for learning from and about people. Here, we used computational modeling and a robot implementation to explore the functional value of action imitation. We report 3 experiments using a mutual imitation task between robots, adults, typically developing children, and children with Autism Spectrum Disorder. We show that a particular learning architecture - specifically one combining artificial neural nets for (i) extraction of visual features, (ii) the robot’s motor internal state, (iii) posture recognition, and (iv) novelty detection - is able to learn from an interactive experience involving mutual imitation. This mutual imitation experience allowed the robot to recognize the interactive agent in a subsequent encounter. These experiments using robots as tools for modeling human cognitive development, based on developmental theory, confirm the promise of developmental robotics. Additionally, findings illustrate how person recognition may emerge through imitative experience, intercorporeal mapping, and statistical learning.

  15. Nurse ethical awareness: Understanding the nature of everyday practice.

    PubMed

    Milliken, Aimee; Grace, Pamela

    2017-08-01

    Much attention has been paid to the role of the nurse in recognizing and addressing ethical dilemmas. There has been less emphasis, however, on the issue of whether or not nurses understand the ethical nature of everyday practice. Awareness of the inherently ethical nature of practice is a component of nurse ethical sensitivity, which has been identified as a component of ethical decision-making. Ethical sensitivity is generally accepted as a necessary precursor to moral agency, in that recognition of the ethical content of practice is necessary before consistent action on behalf of patient interests can take place. This awareness is also compulsory in ensuring patient good by recognizing the unique interests and wishes of individuals, in line with an ethic of care. Scholarly and research literature are used to argue that bolstering ethical awareness and ensuring that nurses understand the ethical nature of the role are an obligation of the profession. Based on this line of reasoning, recommendations for education and practice, along with directions for future research, are suggested.

  16. Individual recognition of human infants on the basis of cries alone.

    PubMed

    Green, J A; Gustafson, G E

    1983-11-01

    Human parents were asked to identify their infants on the basis of tape-recorded cries that they had not previously heard. The cries of twenty 30-day-old infants were recorded just prior to a feeding, then rerecorded onto a test tape containing cries from three other infants. Eighty percent of mothers were able to recognize their infants' cries, as were 45% of fathers. An additional 140 adults (non-parents) were tested in order to determine if the process of dubbing cries onto test tapes had left extraneous auditory cues to infants' identities and if the foil infants were equally discriminable. The results indicated that parents' recognition was not based on extraneous cues and that, overall, the foils were appropriate distractors in the parents' task. Thus, the majority of parents can recognize their 30-day-old infants on the sole basis of acoustic cues contained in the infants' cries. The acoustic features that underlie this recognition are now being investigated.

  17. Robots Learn to Recognize Individuals from Imitative Encounters with People and Avatars

    PubMed Central

    Boucenna, Sofiane; Cohen, David; Meltzoff, Andrew N.; Gaussier, Philippe; Chetouani, Mohamed

    2016-01-01

    Prior to language, human infants are prolific imitators. Developmental science grounds infant imitation in the neural coding of actions, and highlights the use of imitation for learning from and about people. Here, we used computational modeling and a robot implementation to explore the functional value of action imitation. We report 3 experiments using a mutual imitation task between robots, adults, typically developing children, and children with Autism Spectrum Disorder. We show that a particular learning architecture - specifically one combining artificial neural nets for (i) extraction of visual features, (ii) the robot’s motor internal state, (iii) posture recognition, and (iv) novelty detection - is able to learn from an interactive experience involving mutual imitation. This mutual imitation experience allowed the robot to recognize the interactive agent in a subsequent encounter. These experiments using robots as tools for modeling human cognitive development, based on developmental theory, confirm the promise of developmental robotics. Additionally, findings illustrate how person recognition may emerge through imitative experience, intercorporeal mapping, and statistical learning. PMID:26844862

  18. Building emotional intelligence: a strategy for emerging nurse leaders to reduce workplace bullying.

    PubMed

    Bennett, Karen; Sawatzky, Jo-Ann V

    2013-01-01

    Bullying is one of the most concerning forms of aggression in health care organizations. Conceptualized as an emotion-based response, bullying is often triggered by today's workplace challenges. Unfortunately, workplace bullying is an escalating problem in nursing. Bullying contributes to unhealthy and toxic environments, which in turn contribute to ineffective patient care, increased stress, and decreased job satisfaction among health care providers. These equate to a poor workforce environment, which in turn increases hospital costs when nurses choose to leave. Nurse managers are in positions of power to recognize and address negative workplace behaviors, such as bullying. However, emerging leaders in particular may not be equipped with the tools to deal with bullying and consequently may choose to overlook it. Substantive evidence from other disciplines supports the contention that individuals with greater emotional intelligence are better equipped to recognize early signs of negative behavior, such as bullying. Therefore, fostering emotional intelligence in emerging nurse leaders may lead to less bullying and more positive workplace environments for nurses in the future.

  19. Individual tree crown delineation using localized contour tree method and airborne LiDAR data in coniferous forests

    NASA Astrophysics Data System (ADS)

    Wu, Bin; Yu, Bailang; Wu, Qiusheng; Huang, Yan; Chen, Zuoqi; Wu, Jianping

    2016-10-01

    Individual tree crown delineation is of great importance for forest inventory and management. The increasing availability of high-resolution airborne light detection and ranging (LiDAR) data makes it possible to delineate the crown structure of individual trees and deduce their geometric properties with high accuracy. In this study, we developed an automated segmentation method that is able to fully utilize high-resolution LiDAR data for detecting, extracting, and characterizing individual tree crowns with a multitude of geometric and topological properties. The proposed approach captures topological structure of forest and quantifies topological relationships of tree crowns by using a graph theory-based localized contour tree method, and finally segments individual tree crowns by analogy of recognizing hills from a topographic map. This approach consists of five key technical components: (1) derivation of canopy height model from airborne LiDAR data; (2) generation of contours based on the canopy height model; (3) extraction of hierarchical structures of tree crowns using the localized contour tree method; (4) delineation of individual tree crowns by segmenting hierarchical crown structure; and (5) calculation of geometric and topological properties of individual trees. We applied our new method to the Medicine Bow National Forest in the southwest of Laramie, Wyoming and the HJ Andrews Experimental Forest in the central portion of the Cascade Range of Oregon, U.S. The results reveal that the overall accuracy of individual tree crown delineation for the two study areas achieved 94.21% and 75.07%, respectively. Our method holds great potential for segmenting individual tree crowns under various forest conditions. Furthermore, the geometric and topological attributes derived from our method provide comprehensive and essential information for forest management.

  20. Individual gregariousness predicts behavioural synchronization in a foraging herbivore, the sheep (Ovis aries).

    PubMed

    Hauschildt, Verena; Gerken, Martina

    2015-04-01

    Diversity of animal personalities has been proposed to arise from differences in social attraction, and to enhance behavioural flexibility of a population. The present study evaluated gregariousness as a personality trait in 14 ewes kept on pasture. Gregariousness was defined based on the frequency of having a close neighbour (<3m). Highly gregarious (HG) and less gregarious (LG) animals were separated into two groups (n=7) which were reintegrated after 18 days. During direct field observations, behaviour was recorded individually every 15 min. Each session lasted 2.5h (08.30-11.00 h or 14.30-17.00 h, respectively). Behavioural synchronization was highest when the group consisted only of HG individuals (κHG=0.69, κLG=0.31; t=5.29; p<0.001), indicating that gregariousness predicted behavioural synchronization in sheep. Though sheep are generally recognized as a highly gregarious species, HG and LG individuals could be differentiated clearly and consistently. Research on animal personality might help explain social influences on behavioural synchronization. Copyright © 2015 Elsevier B.V. All rights reserved.

  1. More than one way to see it: Individual heuristics in avian visual computation

    PubMed Central

    Ravignani, Andrea; Westphal-Fitch, Gesche; Aust, Ulrike; Schlumpp, Martin M.; Fitch, W. Tecumseh

    2015-01-01

    Comparative pattern learning experiments investigate how different species find regularities in sensory input, providing insights into cognitive processing in humans and other animals. Past research has focused either on one species’ ability to process pattern classes or different species’ performance in recognizing the same pattern, with little attention to individual and species-specific heuristics and decision strategies. We trained and tested two bird species, pigeons (Columba livia) and kea (Nestor notabilis, a parrot species), on visual patterns using touch-screen technology. Patterns were composed of several abstract elements and had varying degrees of structural complexity. We developed a model selection paradigm, based on regular expressions, that allowed us to reconstruct the specific decision strategies and cognitive heuristics adopted by a given individual in our task. Individual birds showed considerable differences in the number, type and heterogeneity of heuristic strategies adopted. Birds’ choices also exhibited consistent species-level differences. Kea adopted effective heuristic strategies, based on matching learned bigrams to stimulus edges. Individual pigeons, in contrast, adopted an idiosyncratic mix of strategies that included local transition probabilities and global string similarity. Although performance was above chance and quite high for kea, no individual of either species provided clear evidence of learning exactly the rule used to generate the training stimuli. Our results show that similar behavioral outcomes can be achieved using dramatically different strategies and highlight the dangers of combining multiple individuals in a group analysis. These findings, and our general approach, have implications for the design of future pattern learning experiments, and the interpretation of comparative cognition research more generally. PMID:26113444

  2. What Is Evidence-Based Behavior Analysis?

    PubMed Central

    Smith, Tristram

    2013-01-01

    Although applied behavior analysts often say they engage in evidence-based practice, they express differing views on what constitutes “evidence” and “practice.” This article describes a practice as a service offered by a provider to help solve a problem presented by a consumer. Solving most problems (e.g., increasing or decreasing a behavior and maintaining this change) requires multiple intervention procedures (i.e., a package). Single-subject studies are invaluable in investigating individual procedures, but researchers still need to integrate the procedures into a package. The package must be standardized enough for independent providers to replicate yet flexible enough to allow individualization; intervention manuals are the primary technology for achieving this balance. To test whether the package is effective in solving consumers' problems, researchers must evaluate outcomes of the package as a whole, usually in group studies such as randomized controlled trials. From this perspective, establishing an evidence-based practice involves more than analyzing the effects of discrete intervention procedures on behavior; it requires synthesizing information so as to offer thorough solutions to problems. Recognizing the need for synthesis offers behavior analysts many promising opportunities to build on their existing research to increase the quality and quantity of evidence-based practices. PMID:25729130

  3. Automatic speech recognition (ASR) based approach for speech therapy of aphasic patients: A review

    NASA Astrophysics Data System (ADS)

    Jamal, Norezmi; Shanta, Shahnoor; Mahmud, Farhanahani; Sha'abani, MNAH

    2017-09-01

    This paper reviews the state-of-the-art an automatic speech recognition (ASR) based approach for speech therapy of aphasic patients. Aphasia is a condition in which the affected person suffers from speech and language disorder resulting from a stroke or brain injury. Since there is a growing body of evidence indicating the possibility of improving the symptoms at an early stage, ASR based solutions are increasingly being researched for speech and language therapy. ASR is a technology that transfers human speech into transcript text by matching with the system's library. This is particularly useful in speech rehabilitation therapies as they provide accurate, real-time evaluation for speech input from an individual with speech disorder. ASR based approaches for speech therapy recognize the speech input from the aphasic patient and provide real-time feedback response to their mistakes. However, the accuracy of ASR is dependent on many factors such as, phoneme recognition, speech continuity, speaker and environmental differences as well as our depth of knowledge on human language understanding. Hence, the review examines recent development of ASR technologies and its performance for individuals with speech and language disorders.

  4. Effect of Amalaki rasayana on DNA damage and repair in randomized aged human individuals.

    PubMed

    Vishwanatha, Udupi; Guruprasad, Kanive P; Gopinath, Puthiya M; Acharya, Raviraj V; Prasanna, Bokkasa V; Nayak, Jayakrishna; Ganesh, Rajeshwari; Rao, Jayalaxmi; Shree, Rashmi; Anchan, Suchitra; Raghu, Kothanahalli S; Joshi, Manjunath B; Paladhi, Puspendu; Varier, Panniampilly M; Muraleedharan, Kollath; Muraleedharan, Thrikovil S; Satyamoorthy, Kapaettu

    2016-09-15

    Preparations from Phyllanthus emblica called Amalaki rasayana is used in the Indian traditional medicinal system of Ayurveda for healthy living in elderly. The biological effects and its mechanisms are not fully understood. Since the diminishing DNA repair is the hallmark of ageing, we tested the influence of Amalaki rasayana on recognized DNA repair activities in healthy aged individuals. Amalaki rasayana was prepared fresh and healthy aged randomized human volunteers were administrated with either rasayana or placebo for 45 days strictly as per the traditional text. The DNA repair was analyzed in peripheral blood mononuclear cells before and after rasayana administration and after 45 days post-rasayana treatment regimen. UVC-induced DNA strand break repair (DSBR) based on extent of DNA unwinding by fluorometric analysis, nucleotide excision repair (NER) by flow cytometry and constitutive base excision repair (BER) by gap filling method were analyzed. Amalaki rasayana administration stably maintained/enhanced the DSBR in aged individuals. There were no adverse side effects. Further, subjects with different body mass index showed differential DNA strand break repair capacity. No change in unscheduled DNA synthesis during NER and BER was observed between the groups. Intake of Amalaki rasayana by aged individuals showed stable maintenance of DNA strand break repair without toxic effects. However, there was no change in nucleotide and base excision repair activities. Results warrant further studies on the effects of Amalaki rasayana on DSBR activities. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  5. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bouchier, F.; Ahrens, J.S.; Wells, G.

    One thing that all access control applications have in common is the need to identify those individuals authorized to gain access to an area. Traditionally, the identification is based on something that person possesses, such as a key or badge, or something they know, such as a PIN or password. Biometric identifiers make their decisions based on the physiological or behavioral characteristics of individuals. The potential of biometrics devices to positively identify individuals has made them attractive for use in access control and computer security applications. However, no systems perform perfectly, so it is important to understand what a biometricmore » device`s performance is under real world conditions before deciding to implement one in an access control system. This paper will describe the evaluation of a prototype biometric identifier provided by IriScan Incorporated. This identifier was developed to recognize individual human beings based on the distinctive visual characteristics of the irises of their eyes. The main goal of the evaluation was to determine whether the system has potential as an access control device within the Department of Energy (DOE). The primary interest was an estimate of the accuracy of the system in terms of false accept and false reject rates. Data was also collected to estimate throughput time and user acceptability. The performance of the system during the test will be discussed. Lessons learned during the test which may aid in further testing and simplify implementation of a production system will also be discussed.« less

  6. Individuals versus organisms versus populations in the definition of ecological assessment endpoints.

    PubMed

    Suter, Glenn W; Norton, Susan B; Fairbrother, Anne

    2005-11-01

    Discussions and applications of the policies and practices of the U.S. Environmental Protection Agency (USEPA) in ecological risk assessment will benefit from continued clarification of the concepts of assessment endpoints and of levels of biological organization. First, assessment endpoint entities and attributes can be defined at different levels of organization. Hence, an organism-level attribute, such as growth or survival, can be applied collectively to a population-level entity such as the brook trout in a stream. Second, assessment endpoints for ecological risk assessment are often mistakenly described as "individual level," which leads to the idea that such assessments are intended to protect individuals. Finally, populations play a more important role in risk assessments than is generally recognized. Organism-level attributes are used primarily for population-level assessments. In addition, the USEPA and other agencies already are basing management decisions on population or community entities and attributes such as production of fisheries, abundance of migratory bird populations, and aquatic community composition.

  7. Individual pay-for-performance in Canadian healthcare organizations.

    PubMed

    Greengarten, Moshe; Hundert, Mark

    2006-01-01

    Pink et al. discuss some of the issues related to pay-for-performance for individual and organizational healthcare providers. This commentary addresses key success factors for the implementation of individual pay-for-performance in publicly financed Canadian healthcare organizations. Publicly financed healthcare organizations in Canada have been relatively slow to adopt performance-pay programs as compared with private sector organizations; and those that have been developed have been, for the most part, rather crude. In many cases, they have become an additional mechanism for delivering base pay, rather than a true variable-pay program that motivates and differentiates performance. In light of the many issues that need to be addressed, we feel that pay-for-performance should be introduced gradually, beginning at the most senior levels of the organization. Above all, it is critical for publicly financed healthcare organizations to recognize that introducing pay-for-performance involves not only a set of structures and processes, but also likely a profound change in organizational values and behaviours.

  8. Knowledge management: implications for human service organizations.

    PubMed

    Austin, Michael J; Claassen, Jennette; Vu, Catherine M; Mizrahi, Paola

    2008-01-01

    Knowledge management has recently taken a more prominent role in the management of organizations as worker knowledge and intellectual capital are recognized as critical to organizational success. This analysis explores the literature of knowledge management including the individual level of tacit and explicit knowledge, the networks and social interactions utilized by workers to create and share new knowledge, and the multiple organizational and managerial factors associated with effective knowledge management systems. Based on the role of organizational culture, structure, leadership, and reward systems, six strategies are identified to assist human service organizations with implementing new knowledge management systems.

  9. Maintaining relationships is critical in network's success.

    PubMed

    Huerta, Timothy

    2006-01-01

    As the authors of the lead paper recognize, networks have become an increasingly popular form of organizing, both in the delivery of public services and within political arenas. A network is an arrangement of individuals and/or organizations that are linked through connections that range from informal relationships to formally agreed protocols. Networks have proved useful in addressing complex and intractable problems that require a holistic approach to identifying and implementing long-term solutions. They succeed in situations where hierarchies and "silo-based" systems have failed, and are particularly valuable in facilitating the transfer of resources and knowledge across sectoral and organizational boundaries.

  10. Miocene actinommid Radiolaria from the equatorial Pacific

    USGS Publications Warehouse

    Blueford, J.R.

    1982-01-01

    Actinommids (spumellarian Radiolaria) are a group of microfossils in which taxonomy and phylogeny hitherto have been based on features of morphology that change with the growth of individuals. To make Miocene actinommids from the equatorial Pacific useful in biostratigraphy, paleocenography, and paleoecology, ontogenetically invariant morphological features can be analyzed by methods of numerical taxonomy to group the specimens into genera, which are further subdivided into species by visual comparison. According to these criteria, 31 species, 18 of which are new, are recognized in the Late Miocene section of DSDP Sites 77 and 289, and an informal revision of actinommid higher taxa is tentatively proposed.

  11. Individual pollen exposure measurements: are they feasible?

    PubMed

    Berger, Uwe; Kmenta, Maximilian; Bastl, Katharina

    2014-06-01

    The purpose of the recent review is to give insight into recent attempts to measure individual pollen exposure and to give advice for interpreting such data. It is well recognized that there are various challenges in monitoring the atmospheric content of pollen in the air. Although pollen data gathered by Hirst type spore traps and evaluated by human expertise are of inestimable value because of long-time data series and as the basic foundation for pollen information services as well as for diagnosis and therapy of pollen allergies, there is a need for more precise information for individual pollen allergy sufferers. Different types of individual pollen exposure measurement samplers are presented, and estimates are offered. Further developments, especially standardization of personal pollen samplers, are needed. Improvements should lead to more usability. Because of a variety of factors, a pollen count will always stay a pollen count, and a pollen forecast is not a symptom forecast, something pollen allergy sufferers actually desire. Thus, a different promising path to individualized pollen information was recently chosen: personal pollen information is now possible based on personal symptom data and regional pollen data. In future, personal pollen data could complete this achievement.

  12. A True-Color Sensor and Suitable Evaluation Algorithm for Plant Recognition

    PubMed Central

    Schmittmann, Oliver; Schulze Lammers, Peter

    2017-01-01

    Plant-specific herbicide application requires sensor systems for plant recognition and differentiation. A literature review reveals a lack of sensor systems capable of recognizing small weeds in early stages of development (in the two- or four-leaf stage) and crop plants, of making spraying decisions in real time and, in addition, are that are inexpensive and ready for practical use in sprayers. The system described in this work is based on free cascadable and programmable true-color sensors for real-time recognition and identification of individual weed and crop plants. The application of this type of sensor is suitable for municipal areas and farmland with and without crops to perform the site-specific application of herbicides. Initially, databases with reflection properties of plants, natural and artificial backgrounds were created. Crop and weed plants should be recognized by the use of mathematical algorithms and decision models based on these data. They include the characteristic color spectrum, as well as the reflectance characteristics of unvegetated areas and areas with organic material. The CIE-Lab color-space was chosen for color matching because it contains information not only about coloration (a- and b-channel), but also about luminance (L-channel), thus increasing accuracy. Four different decision making algorithms based on different parameters are explained: (i) color similarity (ΔE); (ii) color similarity split in ΔL, Δa and Δb; (iii) a virtual channel ‘d’ and (iv) statistical distribution of the differences of reflection backgrounds and plants. Afterwards, the detection success of the recognition system is described. Furthermore, the minimum weed/plant coverage of the measuring spot was calculated by a mathematical model. Plants with a size of 1–5% of the spot can be recognized, and weeds in the two-leaf stage can be identified with a measuring spot size of 5 cm. By choosing a decision model previously, the detection quality can be increased. Depending on the characteristics of the background, different models are suitable. Finally, the results of field trials on municipal areas (with models of plants), winter wheat fields (with artificial plants) and grassland (with dock) are shown. In each experimental variant, objects and weeds could be recognized. PMID:28786922

  13. A True-Color Sensor and Suitable Evaluation Algorithm for Plant Recognition.

    PubMed

    Schmittmann, Oliver; Schulze Lammers, Peter

    2017-08-08

    Plant-specific herbicide application requires sensor systems for plant recognition and differentiation. A literature review reveals a lack of sensor systems capable of recognizing small weeds in early stages of development (in the two- or four-leaf stage) and crop plants, of making spraying decisions in real time and, in addition, are that are inexpensive and ready for practical use in sprayers. The system described in this work is based on free cascadable and programmable true-color sensors for real-time recognition and identification of individual weed and crop plants. The application of this type of sensor is suitable for municipal areas and farmland with and without crops to perform the site-specific application of herbicides. Initially, databases with reflection properties of plants, natural and artificial backgrounds were created. Crop and weed plants should be recognized by the use of mathematical algorithms and decision models based on these data. They include the characteristic color spectrum, as well as the reflectance characteristics of unvegetated areas and areas with organic material. The CIE-Lab color-space was chosen for color matching because it contains information not only about coloration (a- and b-channel), but also about luminance (L-channel), thus increasing accuracy. Four different decision making algorithms based on different parameters are explained: (i) color similarity (ΔE); (ii) color similarity split in ΔL, Δa and Δb; (iii) a virtual channel 'd' and (iv) statistical distribution of the differences of reflection backgrounds and plants. Afterwards, the detection success of the recognition system is described. Furthermore, the minimum weed/plant coverage of the measuring spot was calculated by a mathematical model. Plants with a size of 1-5% of the spot can be recognized, and weeds in the two-leaf stage can be identified with a measuring spot size of 5 cm. By choosing a decision model previously, the detection quality can be increased. Depending on the characteristics of the background, different models are suitable. Finally, the results of field trials on municipal areas (with models of plants), winter wheat fields (with artificial plants) and grassland (with dock) are shown. In each experimental variant, objects and weeds could be recognized.

  14. Prevalence of sleep bruxism and awake bruxism in different chronotype profiles: Hypothesis of an association.

    PubMed

    Serra-Negra, J M; Lobbezoo, F; Martins, C C; Stellini, E; Manfredini, D

    2017-04-01

    Sleep (SB) and awake bruxism (AB) recognize a multifactorial etiology and have a relationship with several psychological factors. Psychological disorders have recently been associated also with the chronotype, which is the propensity for an individual to be especially active at a particular time during a 24-h period. Based on the chronotype, the two extreme profiles are morningness and eveningness individuals. Due to the relationship that both the chronotype and bruxism have with psychological factors and the fact that performing tasks not compatible with chronotype can trigger stress, this review presents the hypothesis that the prevalence of SB and AB can differ with the various chronotype profiles. New perspectives for the study of bruxism etiology may emerge from investigations on the topic. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Motivational interviewing for HIV risk reduction among gay men in commercial and public sex settings.

    PubMed

    Harding, R; Dockrell, M J; Dockrell, J; Corrigan, N

    2001-08-01

    The present paper addresses the feasibility of combining motivational interviewing and cognitive interventions to HIV risk reduction in commercial venues and public sex environments (PSEs). The logic for these two approaches is considered and an intervention combining key elements of the two is presented. The intervention uses a questionnaire format to encourage individuals to compare their desired versus actual behaviour (i.e. chosen personal risk reduction strategy versus 'slip-ups'/unwanted risk taking), and to recognize their risk-related cognitions. High-risk individuals are identified, and health-focused conversations developed from the brief schedule. The structure and key design issues in the development of a feasible, acceptable and evidence-based tool are reviewed. The limitations of more complex, focused interventions in the context of commercial and PSE settings are discussed.

  16. Implementing sustainability: the behavioral-institutional dimension

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Malone, Elizabeth L.; Diamond, Rick C.; Wolfe, Amy K.

    2013-05-10

    Organizations, both public and private sector, are increasingly pursuing strategies to reduce their energy use and increase sustainability. Whether these efforts are based on economic rationale, community spirit, environmental ethics, federal mandates, or other reasons, they predominantly feature strategies that rely on new technologies. If there is any focus on behavior change, it is typically addressed to changing individual behavior. While we recognize the importance—and limitations—of the role of individual behavior in promoting sustainability goals, we are more interested in the role of institutional behavior. We have reviewed the small but growing literature on institutional behavior change, and have identifiedmore » eight “evidence-based” principles as a guide for federal agencies to take action. This article presents the principles and illustrates them with examples to suggest ways that they can serve as models for others.« less

  17. Molecular exploration of hidden diversity in the Indo-West Pacific sciaenid clade

    PubMed Central

    Lo, Pei-Chun; Liu, Shu-Hui; Nor, Siti Azizah Mohd

    2017-01-01

    The family Sciaenidae, known as croakers or drums, is one of the largest perciform fish families. A recent multi-gene based study investigating the phylogeny and biogeography of global sciaenids revealed that the origin and early diversification of this family occurred in tropical America during the Late Oligocene—Early Miocene before undergoing range expansions to other seas including the Indo-West Pacific, where high species richness is observed. Despite this clarification of the overall evolutionary history of the family, knowledge of the taxonomy and phylogeny of sciaenid genera endemic to the Indo-West Pacific is still limited due to lack of a thorough survey of all taxa. In this study, we used DNA-based approaches to investigate the evolutionary relationships, to explore the species diversity, and to elucidate the taxonomic status of sciaenid species/genera within the Indo-West Pacific clade. Three datasets were herein built for the above objectives: the combined dataset (248 samples from 45 currently recognized species) from one nuclear gene (RAG1) and one mitochondrial gene (COI); the dataset with only RAG1 gene sequences (245 samples from 44 currently recognized species); and the dataset with only COI gene sequences (308 samples from 51 currently recognized species). The latter was primarily used for our biodiversity exploration with two different species delimitation methods (Automatic Barcode Gap Discovery, ABGD and Generalized Mixed Yule Coalescent, GMYC). The results were further evaluated with help of four supplementary criteria for species delimitation (genetic similarity, monophyly inferred from individual gene and combined data trees, geographic distribution, and morphology). Our final results confirmed the validity of 32 currently recognized species and identified several potential new species waiting for formal descriptions. We also reexamined the taxonomic status of the genera, Larimichthys, Nibea, Protonibea and Megalonibea, and suggested a revision of Nibea and proposed a new genus Pseudolarimichthys. PMID:28453569

  18. Molecular exploration of hidden diversity in the Indo-West Pacific sciaenid clade.

    PubMed

    Lo, Pei-Chun; Liu, Shu-Hui; Nor, Siti Azizah Mohd; Chen, Wei-Jen

    2017-01-01

    The family Sciaenidae, known as croakers or drums, is one of the largest perciform fish families. A recent multi-gene based study investigating the phylogeny and biogeography of global sciaenids revealed that the origin and early diversification of this family occurred in tropical America during the Late Oligocene-Early Miocene before undergoing range expansions to other seas including the Indo-West Pacific, where high species richness is observed. Despite this clarification of the overall evolutionary history of the family, knowledge of the taxonomy and phylogeny of sciaenid genera endemic to the Indo-West Pacific is still limited due to lack of a thorough survey of all taxa. In this study, we used DNA-based approaches to investigate the evolutionary relationships, to explore the species diversity, and to elucidate the taxonomic status of sciaenid species/genera within the Indo-West Pacific clade. Three datasets were herein built for the above objectives: the combined dataset (248 samples from 45 currently recognized species) from one nuclear gene (RAG1) and one mitochondrial gene (COI); the dataset with only RAG1 gene sequences (245 samples from 44 currently recognized species); and the dataset with only COI gene sequences (308 samples from 51 currently recognized species). The latter was primarily used for our biodiversity exploration with two different species delimitation methods (Automatic Barcode Gap Discovery, ABGD and Generalized Mixed Yule Coalescent, GMYC). The results were further evaluated with help of four supplementary criteria for species delimitation (genetic similarity, monophyly inferred from individual gene and combined data trees, geographic distribution, and morphology). Our final results confirmed the validity of 32 currently recognized species and identified several potential new species waiting for formal descriptions. We also reexamined the taxonomic status of the genera, Larimichthys, Nibea, Protonibea and Megalonibea, and suggested a revision of Nibea and proposed a new genus Pseudolarimichthys.

  19. Working under a clinic-level quality incentive: primary care clinicians' perceptions.

    PubMed

    Greene, Jessica; Kurtzman, Ellen T; Hibbard, Judith H; Overton, Valerie

    2015-01-01

    A key consideration in designing pay-for-performance programs is determining what entity the incentive should be awarded to-individual clinicians or to groups of clinicians working in teams. Some argue that team-level incentives, in which clinicians who are part of a team receive the same incentive based on the team's performance, are most effective; others argue for the efficacy of clinician-level incentives. This study examines primary care clinicians' perceptions of a team-based quality incentive awarded at the clinic level. This research was conducted with Fairview Health Services, where 40% of the primary care compensation model was based on clinic-level quality performance. We conducted 48 in-depth interviews to explore clinicians' perceptions of the clinic-level incentive, as well as an online survey of 150 clinicians (response rate 56%) to investigate which entity the clinicians would consider optimal to target for quality incentives. Clinicians reported the strengths of the clinic-based quality incentive were quality improvement for the team and less patient "dumping," or shifting patients with poor outcomes to other clinicians. The weaknesses were clinicians' lack of control and colleagues riding the coattails of higher performers. There were mixed reports on the model's impact on team dynamics. Although clinicians reported greater interaction with colleagues, some described an increase in tension. Most clinicians surveyed (73%) believed that there should be a mix of clinic and individual-level incentives to maintain collaboration and recognize individual performance. The study highlights the important advantages and disadvantages of using incentives based upon clinic-level performance. Future research should test whether hybrid incentives that mix group and individual incentives can maintain some of the best elements of each design while mitigating the negative impacts. © 2015 Annals of Family Medicine, Inc.

  20. Recognition of flow in everyday life using sensor agent robot with laser range finder

    NASA Astrophysics Data System (ADS)

    Goshima, Misa; Mita, Akira

    2011-04-01

    In the present paper, we suggest an algorithm for a sensor agent robot with a laser range finder to recognize the flows of residents in the living spaces in order to achieve flow recognition in the living spaces, recognition of the number of people in spaces, and the classification of the flows. House reform is or will be demanded to prolong the lifetime of the home. Adaption for the individuals is needed for our aging society which is growing at a rapid pace. Home autonomous mobile robots will become popular in the future for aged people to assist them in various situations. Therefore we have to collect various type of information of human and living spaces. However, a penetration in personal privacy must be avoided. It is essential to recognize flows in everyday life in order to assist house reforms and aging societies in terms of adaption for the individuals. With background subtraction, extra noise removal, and the clustering based k-means method, we got an average accuracy of more than 90% from the behavior from 1 to 3 persons, and also confirmed the reliability of our system no matter the position of the sensor. Our system can take advantages from autonomous mobile robots and protect the personal privacy. It hints at a generalization of flow recognition methods in the living spaces.

  1. Do Older Listeners With Hearing Loss Benefit From Dynamic Pitch for Speech Recognition in Noise?

    PubMed

    Shen, Jing; Souza, Pamela E

    2017-10-12

    Dynamic pitch, the variation in the fundamental frequency of speech, aids older listeners' speech perception in noise. It is unclear, however, whether some older listeners with hearing loss benefit from strengthened dynamic pitch cues for recognizing speech in certain noise scenarios and how this relative benefit may be associated with individual factors. We first examined older individuals' relative benefit between natural and strong dynamic pitches for better speech recognition in noise. Further, we reported the individual factors of the 2 groups of listeners who benefit differently from natural and strong dynamic pitches. Speech reception thresholds of 13 older listeners with mild-moderate hearing loss were measured using target speech with 3 levels of dynamic pitch strength. Individuals' ability to benefit from dynamic pitch was defined as the speech reception threshold difference between speeches with and without dynamic pitch cues. The relative benefit of natural versus strong dynamic pitch varied across individuals. However, this relative benefit remained consistent for the same individuals across those background noises with temporal modulation. Those listeners who benefited more from strong dynamic pitch reported better subjective speech perception abilities. Strong dynamic pitch may be more beneficial than natural dynamic pitch for some older listeners to recognize speech better in noise, particularly when the noise has temporal modulation.

  2. Key Concepts of Environmental Sustainability in Family and Consumer Sciences

    ERIC Educational Resources Information Center

    Thompson, Nancy E.; Harden, Amy J.; Clauss, Barbara; Fox, Wanda S.; Wild, Peggy

    2012-01-01

    It is the vision of the American Association of Family & Consumer Sciences to be "recognized as the driving force in bringing people together to improve the lives of individuals, families, and communities" (AAFCS, 2010). Because of this focus on individuals and families and its well-established presence in American schools, family and consumer…

  3. Individual Literacy Activities with Hearing-Impaired Children in the Preschool Period

    ERIC Educational Resources Information Center

    Karasu, H. Pelin

    2014-01-01

    The ability to recognize sight words, phonological awareness, syntax, semantics, and pragmatic skills begins to develop during the preschool period, and is important for formal reading education. The purpose of this study was to define individualized studies that support the development of literacy skills among hearing-impaired preschool children.…

  4. Predictors of Support for Juvenile Sex Offender Registration: Educated Individuals Recognize the Flaws of Juvenile Registration

    ERIC Educational Resources Information Center

    Stevenson, Margaret C.; Smith, Amy C.; Sekely, Ady; Farnum, Katlyn S.

    2013-01-01

    We investigated demographic predictors of support for juvenile sex offender registration policies, including education level, gender, political orientation, and age. Participants were 168 individuals recruited from public places in a Midwest community (45% women; M age = 42). In line with hypotheses, as education level increased, support for…

  5. Convergence, Competition, Cooperation: The Report of the Governor's Blue Ribbon Telecommunications Infrastructure Task Force. Volume One.

    ERIC Educational Resources Information Center

    Wisconsin Governor's Office, Madison.

    This report by the Blue Ribbon Task Force on Wisconsin's Telecommunications Infrastructure considers infrastructure to be the common network that connects individual residences, businesses, and agencies, rather than the individual systems and equipment themselves. The task force recognizes that advances in telecommunications technologies and…

  6. Lived History of a Transformative Leader with a Disability: An Evocative Autoethnography for Social Justice

    ERIC Educational Resources Information Center

    Vergara, Sofia

    2017-01-01

    Despite legal advancements recognizing the rights of individuals with disabilities, societal barriers are still arising from the medical model of disability. These obstacles have resulted in marginalizing and isolating practices, in turn leading to the underrepresentation of individuals with disabilities in the workforce and, by extension, in…

  7. 26 CFR 601.502 - Recognized representative.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    .... 230; (4) Enrolled actuary. Any individual who is enrolled as an actuary by and is in active status with the Joint Board for the Enrollment of Actuaries pursuant to 29 U.S.C. 1242. (5) Other individuals... actuaries, and others); (3) I am authorized to represent the taxpayer(s) identified in the power of attorney...

  8. 26 CFR 601.502 - Recognized representative.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    .... 230; (4) Enrolled actuary. Any individual who is enrolled as an actuary by and is in active status with the Joint Board for the Enrollment of Actuaries pursuant to 29 U.S.C. 1242. (5) Other individuals... actuaries, and others); (3) I am authorized to represent the taxpayer(s) identified in the power of attorney...

  9. 26 CFR 601.502 - Recognized representative.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    .... 230; (4) Enrolled actuary. Any individual who is enrolled as an actuary by and is in active status with the Joint Board for the Enrollment of Actuaries pursuant to 29 U.S.C. 1242. (5) Other individuals... actuaries, and others); (3) I am authorized to represent the taxpayer(s) identified in the power of attorney...

  10. 26 CFR 601.502 - Recognized representative.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    .... 230; (4) Enrolled actuary. Any individual who is enrolled as an actuary by and is in active status with the Joint Board for the Enrollment of Actuaries pursuant to 29 U.S.C. 1242. (5) Other individuals... actuaries, and others); (3) I am authorized to represent the taxpayer(s) identified in the power of attorney...

  11. Strategies for Individualizing Instruction across the Disciplines for the Culturally Diverse Learner.

    ERIC Educational Resources Information Center

    Smith, Ann

    Educational institutions need to recognize and accommodate the individual needs of learners from culturally diverse backgrounds, of whom a large number are Blacks and Hispanics. To accommodate the educational needs of these learners, educators need to build on their entry-level strengths, which have been identified as: (1) orientation toward…

  12. Degraded character recognition based on gradient pattern

    NASA Astrophysics Data System (ADS)

    Babu, D. R. Ramesh; Ravishankar, M.; Kumar, Manish; Wadera, Kevin; Raj, Aakash

    2010-02-01

    Degraded character recognition is a challenging problem in the field of Optical Character Recognition (OCR). The performance of an optical character recognition depends upon printed quality of the input documents. Many OCRs have been designed which correctly identifies the fine printed documents. But, very few reported work has been found on the recognition of the degraded documents. The efficiency of the OCRs system decreases if the input image is degraded. In this paper, a novel approach based on gradient pattern for recognizing degraded printed character is proposed. The approach makes use of gradient pattern of an individual character for recognition. Experiments were conducted on character image that is either digitally written or a degraded character extracted from historical documents and the results are found to be satisfactory.

  13. Online Learners’ Reading Ability Detection Based on Eye-Tracking Sensors

    PubMed Central

    Zhan, Zehui; Zhang, Lei; Mei, Hu; Fong, Patrick S. W.

    2016-01-01

    The detection of university online learners’ reading ability is generally problematic and time-consuming. Thus the eye-tracking sensors have been employed in this study, to record temporal and spatial human eye movements. Learners’ pupils, blinks, fixation, saccade, and regression are recognized as primary indicators for detecting reading abilities. A computational model is established according to the empirical eye-tracking data, and applying the multi-feature regularization machine learning mechanism based on a Low-rank Constraint. The model presents good generalization ability with an error of only 4.9% when randomly running 100 times. It has obvious advantages in saving time and improving precision, with only 20 min of testing required for prediction of an individual learner’s reading ability. PMID:27626418

  14. Captive Bottlenose Dolphins Do Discriminate Human-Made Sounds Both Underwater and in the Air.

    PubMed

    Lima, Alice; Sébilleau, Mélissa; Boye, Martin; Durand, Candice; Hausberger, Martine; Lemasson, Alban

    2018-01-01

    Bottlenose dolphins ( Tursiops truncatus ) spontaneously emit individual acoustic signals that identify them to group members. We tested whether these cetaceans could learn artificial individual sound cues played underwater and whether they would generalize this learning to airborne sounds. Dolphins are thought to perceive only underwater sounds and their training depends largely on visual signals. We investigated the behavioral responses of seven dolphins in a group to learned human-made individual sound cues, played underwater and in the air. Dolphins recognized their own sound cue after hearing it underwater as they immediately moved toward the source, whereas when it was airborne they gazed more at the source of their own sound cue but did not approach it. We hypothesize that they perhaps detected modifications of the sound induced by air or were confused by the novelty of the situation, but nevertheless recognized they were being "targeted." They did not respond when hearing another group member's cue in either situation. This study provides further evidence that dolphins respond to individual-specific sounds and that these marine mammals possess some capacity for processing airborne acoustic signals.

  15. Cleft Palate Foundation

    MedlinePlus

    ... be postmarked by Oct. 31st. ACPA Family Services Leadership Award ACPA Family Services is now accepting nominations for the 2018 Leadership Award, which recognizes individuals or groups who have ...

  16. Life on Earth is an individual.

    PubMed

    Hermida, Margarida

    2016-06-01

    Life is a self-maintaining process based on metabolism. Something is said to be alive when it exhibits organization and is actively involved in its own continued existence through carrying out metabolic processes. A life is a spatio-temporally restricted event, which continues while the life processes are occurring in a particular chunk of matter (or, arguably, when they are temporally suspended, but can be restarted at any moment), even though there is continuous replacement of parts. Life is organized in discrete packages, particular cells and multicellular organisms with differing degrees of individuality. Biological species, too, have been shown to be individuals, and not classes, as these collections of organisms are spatio-temporally localized, restricted, continuous, and somewhat cohesive entities, with a definite beginning and end. Assuming that all life on Earth has a common origin, all living organisms, cells, and tissues descending from this origin exhibit continuity of the life processes at the cellular level, as well as many of the features that define the individual character of species: spatio-temporal localization and restriction, continuity, historicity, and cohesiveness. Therefore, life on Earth is an ontological individual. Independent origins of life will have produced other such individuals. These provisionally called 'life-individuals' constitute a category of organization of life which has seldom been recognized. The discovery of at least one independent life-individual would go a long way toward the project of the universality of biology.

  17. Analyte species and concentration identification using differentially functionalized microcantilever arrays and artificial neural networks

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Senesac, Larry R; Datskos, Panos G; Sepaniak, Michael J

    2006-01-01

    In the present work, we have performed analyte species and concentration identification using an array of ten differentially functionalized microcantilevers coupled with a back-propagation artificial neural network pattern recognition algorithm. The array consists of ten nanostructured silicon microcantilevers functionalized by polymeric and gas chromatography phases and macrocyclic receptors as spatially dense, differentially responding sensing layers for identification and quantitation of individual analyte(s) and their binary mixtures. The array response (i.e. cantilever bending) to analyte vapor was measured by an optical readout scheme and the responses were recorded for a selection of individual analytes as well as several binary mixtures. Anmore » artificial neural network (ANN) was designed and trained to recognize not only the individual analytes and binary mixtures, but also to determine the concentration of individual components in a mixture. To the best of our knowledge, ANNs have not been applied to microcantilever array responses previously to determine concentrations of individual analytes. The trained ANN correctly identified the eleven test analyte(s) as individual components, most with probabilities greater than 97%, whereas it did not misidentify an unknown (untrained) analyte. Demonstrated unique aspects of this work include an ability to measure binary mixtures and provide both qualitative (identification) and quantitative (concentration) information with array-ANN-based sensor methodologies.« less

  18. A Mis-recognized Medical Vocabulary Correction System for Speech-based Electronic Medical Record

    PubMed Central

    Seo, Hwa Jeong; Kim, Ju Han; Sakabe, Nagamasa

    2002-01-01

    Speech recognition as an input tool for electronic medical record (EMR) enables efficient data entry at the point of care. However, the recognition accuracy for medical vocabulary is much poorer than that for doctor-patient dialogue. We developed a mis-recognized medical vocabulary correction system based on syllable-by-syllable comparison of speech text against medical vocabulary database. Using specialty medical vocabulary, the algorithm detects and corrects mis-recognized medical vocabularies in narrative text. Our preliminary evaluation showed 94% of accuracy in mis-recognized medical vocabulary correction.

  19. Statistical Physics Approaches to RNA Editing

    NASA Astrophysics Data System (ADS)

    Bundschuh, Ralf

    2012-02-01

    The central dogma of molecular Biology states that DNA is transcribed base by base into RNA which is in turn translated into proteins. However, some organisms edit their RNA before translation by inserting, deleting, or substituting individual or short stretches of bases. In many instances the mechanisms by which an organism recognizes the positions at which to edit or by which it performs the actual editing are unknown. One model system that stands out by its very high rate of on average one out of 25 bases being edited are the Myxomycetes, a class of slime molds. In this talk we will show how the computational methods and concepts from statistical Physics can be used to analyze DNA and protein sequence data to predict editing sites in these slime molds and to guide experiments that identified previously unknown types of editing as well as the complete set of editing events in the slime mold Physarum polycephalum.

  20. Climate Change and Political Action: the Citizens' Climate Lobby

    NASA Astrophysics Data System (ADS)

    Nelson, P. H.; Secord, S.

    2014-12-01

    Recognizing the reality of global warming and its origin in greenhouse gas emissions, what does one do about it? Individual action is commendable, but inadequate. Collective action is necessary--Citizens' Climate Lobby proposes a "fee-and-dividend" approach in which a fee is imposed on carbon-based fuel at its sources of production. The fee increases annually in a predictable manner. The funds collected are paid out to consumers as monthly dividends. The approach is market-based, in that the cost of the fee to producers is passed on to consumers in the cost of carbon-based fuels. Downstream energy providers and consumers then make their choices regarding investments and purchases. Citizens' Climate Lobby (CCL) builds national consensus by growing local Chapters, led and populated by volunteers. The Chapters are charged with public education and presenting the fee-and-dividend proposal to their respective Representatives and Senators. CCL builds trust by its non-partisan approach, meeting with all members of Congress regardless of party affiliation and stance on climate-related issues. CCL also builds trust by a non-confrontational approach, seeking to understand rather than to oppose. CCL works both locally, through its local Chapters, and nationally, with an annual conference in Washington DC during which all Congressional offices are visited. CCL recognizes that a long-term, sustained effort is necessary to address climate change.

  1. A dictionary to identify small molecules and drugs in free text.

    PubMed

    Hettne, Kristina M; Stierum, Rob H; Schuemie, Martijn J; Hendriksen, Peter J M; Schijvenaars, Bob J A; Mulligen, Erik M van; Kleinjans, Jos; Kors, Jan A

    2009-11-15

    From the scientific community, a lot of effort has been spent on the correct identification of gene and protein names in text, while less effort has been spent on the correct identification of chemical names. Dictionary-based term identification has the power to recognize the diverse representation of chemical information in the literature and map the chemicals to their database identifiers. We developed a dictionary for the identification of small molecules and drugs in text, combining information from UMLS, MeSH, ChEBI, DrugBank, KEGG, HMDB and ChemIDplus. Rule-based term filtering, manual check of highly frequent terms and disambiguation rules were applied. We tested the combined dictionary and the dictionaries derived from the individual resources on an annotated corpus, and conclude the following: (i) each of the different processing steps increase precision with a minor loss of recall; (ii) the overall performance of the combined dictionary is acceptable (precision 0.67, recall 0.40 (0.80 for trivial names); (iii) the combined dictionary performed better than the dictionary in the chemical recognizer OSCAR3; (iv) the performance of a dictionary based on ChemIDplus alone is comparable to the performance of the combined dictionary. The combined dictionary is freely available as an XML file in Simple Knowledge Organization System format on the web site http://www.biosemantics.org/chemlist.

  2. Discriminative latent models for recognizing contextual group activities.

    PubMed

    Lan, Tian; Wang, Yang; Yang, Weilong; Robinovitch, Stephen N; Mori, Greg

    2012-08-01

    In this paper, we go beyond recognizing the actions of individuals and focus on group activities. This is motivated from the observation that human actions are rarely performed in isolation; the contextual information of what other people in the scene are doing provides a useful cue for understanding high-level activities. We propose a novel framework for recognizing group activities which jointly captures the group activity, the individual person actions, and the interactions among them. Two types of contextual information, group-person interaction and person-person interaction, are explored in a latent variable framework. In particular, we propose three different approaches to model the person-person interaction. One approach is to explore the structures of person-person interaction. Differently from most of the previous latent structured models, which assume a predefined structure for the hidden layer, e.g., a tree structure, we treat the structure of the hidden layer as a latent variable and implicitly infer it during learning and inference. The second approach explores person-person interaction in the feature level. We introduce a new feature representation called the action context (AC) descriptor. The AC descriptor encodes information about not only the action of an individual person in the video, but also the behavior of other people nearby. The third approach combines the above two. Our experimental results demonstrate the benefit of using contextual information for disambiguating group activities.

  3. Discriminative Latent Models for Recognizing Contextual Group Activities

    PubMed Central

    Lan, Tian; Wang, Yang; Yang, Weilong; Robinovitch, Stephen N.; Mori, Greg

    2012-01-01

    In this paper, we go beyond recognizing the actions of individuals and focus on group activities. This is motivated from the observation that human actions are rarely performed in isolation; the contextual information of what other people in the scene are doing provides a useful cue for understanding high-level activities. We propose a novel framework for recognizing group activities which jointly captures the group activity, the individual person actions, and the interactions among them. Two types of contextual information, group-person interaction and person-person interaction, are explored in a latent variable framework. In particular, we propose three different approaches to model the person-person interaction. One approach is to explore the structures of person-person interaction. Differently from most of the previous latent structured models, which assume a predefined structure for the hidden layer, e.g., a tree structure, we treat the structure of the hidden layer as a latent variable and implicitly infer it during learning and inference. The second approach explores person-person interaction in the feature level. We introduce a new feature representation called the action context (AC) descriptor. The AC descriptor encodes information about not only the action of an individual person in the video, but also the behavior of other people nearby. The third approach combines the above two. Our experimental results demonstrate the benefit of using contextual information for disambiguating group activities. PMID:22144516

  4. Kinetics of HIV-1 CTL epitopes recognized by HLA I alleles in HIV-infected individuals at times near primary infection: the Provir/Latitude45 study.

    PubMed

    Papuchon, Jennifer; Pinson, Patricia; Guidicelli, Gwenda-Line; Bellecave, Pantxika; Thomas, Réjean; LeBlanc, Roger; Reigadas, Sandrine; Taupin, Jean-Luc; Baril, Jean Guy; Routy, Jean Pierre; Wainberg, Mark; Fleury, Hervé

    2014-01-01

    In patients responding successfully to ART, the next therapeutic step is viral cure. An interesting strategy is antiviral vaccination, particularly involving CD8 T cell epitopes. However, attempts at vaccination are dependent on the immunogenetic background of individuals. The Provir/Latitude 45 project aims to investigate which CTL epitopes in proviral HIV-1 will be recognized by the immune system when HLA alleles are taken into consideration. A prior study (Papuchon et al, PLoS ONE 2013) showed that chronically-infected patients under successful ART exhibited variations of proviral CTL epitopes compared to a reference viral strain (HXB2) and that a generic vaccine may not be efficient. Here, we investigated viral and/or proviral CTL epitopes at different time points in recently infected individuals of the Canadian primary HIV infection cohort and assessed the affinity of these epitopes for HLA alleles during the study period. An analysis of the results confirms that it is not possible to fully predict which epitopes will be recognized by the HLA alleles of the patients if the reference sequences and epitopes are taken as the basis of simulation. Epitopes may be seen to vary in circulating RNA and proviral DNA. Despite this confirmation, the overall variability of the epitopes was low in these patients who are temporally close to primary infection.

  5. Kinetics of HIV-1 CTL Epitopes Recognized by HLA I Alleles in HIV-Infected Individuals at Times near Primary Infection: The Provir/Latitude45 Study

    PubMed Central

    Papuchon, Jennifer; Pinson, Patricia; Guidicelli, Gwenda-Line; Bellecave, Pantxika; Thomas, Réjean; LeBlanc, Roger; Reigadas, Sandrine; Taupin, Jean-Luc; Baril, Jean Guy; Routy, Jean Pierre; Wainberg, Mark; Fleury, Hervé

    2014-01-01

    In patients responding successfully to ART, the next therapeutic step is viral cure. An interesting strategy is antiviral vaccination, particularly involving CD8 T cell epitopes. However, attempts at vaccination are dependent on the immunogenetic background of individuals. The Provir/Latitude 45 project aims to investigate which CTL epitopes in proviral HIV-1 will be recognized by the immune system when HLA alleles are taken into consideration. A prior study (Papuchon et al, PLoS ONE 2013) showed that chronically-infected patients under successful ART exhibited variations of proviral CTL epitopes compared to a reference viral strain (HXB2) and that a generic vaccine may not be efficient. Here, we investigated viral and/or proviral CTL epitopes at different time points in recently infected individuals of the Canadian primary HIV infection cohort and assessed the affinity of these epitopes for HLA alleles during the study period. An analysis of the results confirms that it is not possible to fully predict which epitopes will be recognized by the HLA alleles of the patients if the reference sequences and epitopes are taken as the basis of simulation. Epitopes may be seen to vary in circulating RNA and proviral DNA. Despite this confirmation, the overall variability of the epitopes was low in these patients who are temporally close to primary infection. PMID:24964202

  6. Efficacy of fipronil for protecting individual pines from mortality attributed to attack by western pine beetle and mountain pine beetle (Coleoptera: Curculionidae, Scolytinae)

    Treesearch

    C.J. Fettig; A.S. Munson; C.I. Jorgenson; D.M. and Grosman

    2010-01-01

    Bark beetles (Coleoptera: C~rculionidae, Scolytinae) are commonly recognized as important tree mortality agents in coniferous forests of the western U.S. Most species feed on the phloem and cambium, or xylem tissue of woody plants; and a few are recognized as the most destructive of all forest insect pests. The last decade has seen elevated levels of bark beetle caused...

  7. The Civil Rights Act of 1991: From Conciliation to Litigation-- How Congress Delegates Lawmaking to the Courts

    DTIC Science & Technology

    1993-04-01

    instead of attacking the causes. The 1991 Act is a law of stratification that encourages racism , sexism , and litigation to further individual goals and...30 D. What About Those Statistics ? ............................ 31 E. Race Norming - The Dos and Don’ts of Test Scores...in Title VII to recognize group rights through a "disparate impact" theory of discrimination. In Griggs v. Duke Power Co.,` the Court recognized that

  8. 5 CFR 451.102 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Definitions. Award means something bestowed or an action taken to recognize and reward individual or team..., performance goals, measurement systems, award formulas, or payout schedules. Award program means the specific...

  9. Knowledge of stroke risk factors and early warning signs of stroke among students enrolled in allied health programs: a pilot study.

    PubMed

    Milner, Abby; Lewis, William J; Ellis, Charles

    2008-01-01

    The inclusion of stroke education modules early in medical school curricula has resulted in improved stroke knowledge in graduate physicians. The success of these programs suggests that allied health professions programs should also consider strategies to improve stroke knowledge in students preparing for allied health careers that also require knowledge of stroke risk factors and early warning signs. Currently, little is known about stroke knowledge in students enrolled in allied health professions programs. 208 first- and second-year students enrolled in allied health programs completed a survey of stroke risk factors and early warning signs of stroke. Risk factor knowledge - 99% identified smoking as a risk factor; 67% identified diabetes; 93% identified high cholesterol; 89% identified age; and 92% identified physical inactivity. Less than 50% of the students identified all 5 risk factors. There were no differences between first- and second-year students in risk factor knowledge. Early warning signs and first response knowledge - 89% recognized sudden confusion or trouble speaking; 94% recognized sudden facial, arm, or leg weakness; 65% recognized sudden vision loss; 82% recognized sudden trouble walking; and 73% recognized sudden headache as early warning signs of stroke. Eighty-one percent recognized calling 9-1-1 as the appropriate first action. However, only 25% recognized all five early warning signs and only 20% recognized all five early warning signs and would call 9-1-1 as the first action. There were differences between first- and second-year students in recognizing 3 of 5 early warning signs and appropriate first action to call 9-1-1. Most students recognized individual stroke risk factors and early warning signs but few recognized multiple risk factors and early warning signs of stroke.

  10. Ethics of Health Research in Communities: Perspectives From the Southwestern United States

    PubMed Central

    Williams, Robert L.; Willging, Cathleen E.; Quintero, Gilbert; Kalishman, Summers; Sussman, Andrew L.; Freeman, William L.

    2010-01-01

    PURPOSE The increasing attention paid to community-based research highlights the question of whether human research protections focused on the individual are adequate to safeguard communities. We conducted a study to explore how community members perceive low-risk health research, the adequacy of human research protection processes, and the ethical conduct of community-based research. METHODS Eighteen focus groups were conducted among rural and urban Hispanic and Native American communities in New Mexico using a semistructured guide. Group transcriptions were analyzed using iterative readings and coding, with review of the analytic summary by group members. RESULTS Although participants recognized the value of health research, many also identified several adverse effects of research in their communities, including social (community and individual labeling, stigmatization, and discrimination) and economic (community job losses, increased insurance rates, and loss of community income). A lack of community beneficence was emphasized by participants who spoke of researchers who fail to communicate results adequately or assist with follow-through. Many group members did not believe current human research and data privacy processes were adequate to protect or assist communities. CONCLUSIONS Ethical review of community-based health research should apply the Belmont principles to communities. Researchers should adopt additional approaches to community-based research by engaging communities as active partners throughout the research process, focusing on community priorities, and taking extra precautions to assure individual and community privacy. Plans for meaningful dissemination of results to communities should be part of the research design. PMID:20843885

  11. Evolution, Convolution, Dissolution: The Rise of Individual Differences in Human Developmental Psychology.

    ERIC Educational Resources Information Center

    Rickman, David L.

    Although it is difficult to ascertain precisely the time at which the study of individual differences became recognized as a specialty within the psychological sciences, there appears to be much agreement among historians that its development was fostered primarily within the United States during the late 19th century. This paper examines the…

  12. Recreation as a Related Service: Focusing on the Quality of Life of Students with Disabilities

    ERIC Educational Resources Information Center

    Diodati, Melissa R.

    2017-01-01

    Leisure participation is influential on the quality of life of individuals. Individuals with disabilities can face barriers in leisure participation, impacting their quality of life. IDEA (2004) recognizes recreation as a related service as one way to enhance the leisure experiences for students with disabilities. The purpose of this embedded case…

  13. Integrating the Study of Conformity and Culture in Humans and Nonhuman Animals

    ERIC Educational Resources Information Center

    Claidiere, Nicolas; Whiten, Andrew

    2012-01-01

    Conformity--defined here by the fact that an individual displays a particular behavior because it is the most frequent the individual witnessed in others--has long been recognized by social psychologists as one of the main categories of social influence. Surprisingly, it is only recently that conformity has become an active topic in animal and…

  14. Between-Individual Variability and Interpretation of Associations between Neurophysiological and Behavioral Measures in Aging Populations: Comment on Salthouse (2011)

    ERIC Educational Resources Information Center

    Rabbitt, Patrick

    2011-01-01

    Salthouse (2011) argued that (a) variance between individuals on cognitive test scores remains constant between 20 and 90 years of age and (b) widely recognized problems of deducing functional relationships from patterns of correlations between measurements become especially severe for neuropsychological indices, especially for gross indices of…

  15. An Integrated, Multidimensional Treatment Model for Individuals Living with HIV, Mental Illness, and Substance Abuse

    ERIC Educational Resources Information Center

    Bouis, Stephanie; Reif, Susan; Whetten, Kathryn; Scovil, Janet; Murray, Andrea; Swartz, Marvin

    2007-01-01

    The challenge of providing effective treatment services for the growing population of HIV-positive individuals who are also dually diagnosed with substance use and mental disorders has only recently been recognized as an important public health concern affecting both HIV treatment and prevention. This article describes a treatment model that was…

  16. Children in the Learning Factory: The Search for a Humanizing Teacher.

    ERIC Educational Resources Information Center

    Flescher, Irwin

    According to this book of "psychological talks to parents and teachers," the American education system is a major social tragedy because it fails to recognize the potential of the individual. Individual differences are often ignored in the "assembly-line" approach to education and labeling children according to test scores is a way of dehumanizing…

  17. Tool to Distinguish Moles from Melanoma

    Cancer.gov

    “Moles to Melanoma: Recognizing the ABCDE Features” presents photos that show changes in individual pigmented lesions over time, and describes the different appearances of moles, dysplastic nevi, and melanomas.

  18. You Look Familiar: How Malaysian Chinese Recognize Faces

    PubMed Central

    Tan, Chrystalle B. Y.; Stephen, Ian D.; Whitehead, Ross; Sheppard, Elizabeth

    2012-01-01

    East Asian and white Western observers employ different eye movement strategies for a variety of visual processing tasks, including face processing. Recent eye tracking studies on face recognition found that East Asians tend to integrate information holistically by focusing on the nose while white Westerners perceive faces featurally by moving between the eyes and mouth. The current study examines the eye movement strategy that Malaysian Chinese participants employ when recognizing East Asian, white Western, and African faces. Rather than adopting the Eastern or Western fixation pattern, Malaysian Chinese participants use a mixed strategy by focusing on the eyes and nose more than the mouth. The combination of Eastern and Western strategies proved advantageous in participants' ability to recognize East Asian and white Western faces, suggesting that individuals learn to use fixation patterns that are optimized for recognizing the faces with which they are more familiar. PMID:22253762

  19. A practical approach for writer-dependent symbol recognition using a writer-independent symbol recognizer.

    PubMed

    LaViola, Joseph J; Zeleznik, Robert C

    2007-11-01

    We present a practical technique for using a writer-independent recognition engine to improve the accuracy and speed while reducing the training requirements of a writer-dependent symbol recognizer. Our writer-dependent recognizer uses a set of binary classifiers based on the AdaBoost learning algorithm, one for each possible pairwise symbol comparison. Each classifier consists of a set of weak learners, one of which is based on a writer-independent handwriting recognizer. During online recognition, we also use the n-best list of the writer-independent recognizer to prune the set of possible symbols and thus reduce the number of required binary classifications. In this paper, we describe the geometric and statistical features used in our recognizer and our all-pairs classification algorithm. We also present the results of experiments that quantify the effect incorporating a writer-independent recognition engine into a writer-dependent recognizer has on accuracy, speed, and user training time.

  20. More than one way to see it: Individual heuristics in avian visual computation.

    PubMed

    Ravignani, Andrea; Westphal-Fitch, Gesche; Aust, Ulrike; Schlumpp, Martin M; Fitch, W Tecumseh

    2015-10-01

    Comparative pattern learning experiments investigate how different species find regularities in sensory input, providing insights into cognitive processing in humans and other animals. Past research has focused either on one species' ability to process pattern classes or different species' performance in recognizing the same pattern, with little attention to individual and species-specific heuristics and decision strategies. We trained and tested two bird species, pigeons (Columba livia) and kea (Nestor notabilis, a parrot species), on visual patterns using touch-screen technology. Patterns were composed of several abstract elements and had varying degrees of structural complexity. We developed a model selection paradigm, based on regular expressions, that allowed us to reconstruct the specific decision strategies and cognitive heuristics adopted by a given individual in our task. Individual birds showed considerable differences in the number, type and heterogeneity of heuristic strategies adopted. Birds' choices also exhibited consistent species-level differences. Kea adopted effective heuristic strategies, based on matching learned bigrams to stimulus edges. Individual pigeons, in contrast, adopted an idiosyncratic mix of strategies that included local transition probabilities and global string similarity. Although performance was above chance and quite high for kea, no individual of either species provided clear evidence of learning exactly the rule used to generate the training stimuli. Our results show that similar behavioral outcomes can be achieved using dramatically different strategies and highlight the dangers of combining multiple individuals in a group analysis. These findings, and our general approach, have implications for the design of future pattern learning experiments, and the interpretation of comparative cognition research more generally. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

  1. Associations of Racial/Ethnic Identities and Religious Affiliation with Suicidal Ideation among Lesbian, Gay, Bisexual, and Questioning Individuals

    PubMed Central

    Lytle, Megan C.; De Luca, Susan M.; Blosnich, John R.; Brownson, Christopher

    2015-01-01

    Background Our aim was to examine the associations of racial/ethnic identity and religious affiliation with suicidal ideation among lesbian, gay, bisexual, and questioning (LGBQ) and heterosexual college students. An additional aim was to determine the prevalence of passive suicidal ideation (i.e., death ideation) and active suicidal ideation among culturally diverse LGBQ individuals. Methods Data from the National Research Consortium probability-based sample of college students from 70 postsecondary institutions (n=24,626) were used to examine active and passive suicidal ideation in the past 12-months and lifetime active suicidal ideation among students by sexual orientation, racial/ethnic identity, and religious affiliation. Results Across most racial/ethnic groups and religious affiliations, LGBQ students were more likely to report active suicidal ideation than non-LGBQ individuals. Among LGBQ students, Latino individuals had lower odds of reporting both past 12-month passive and active suicidal ideation than their non-Hispanic white LGBQ counterparts. Compared to Christian LGBQ students, Agnostic/Atheist LGBQ individuals had greater odds of reporting past 12-month passive suicidal ideation, and Jewish LGBQ students were less likely to endorse past 12-month passive and active suicidal ideation. Limitations Cross-sectional design and self-reported data. Conclusions Results corroborate previous research showing elevated prevalence of suicidal ideation among LGBQ individuals in comparison to their heterosexual counterparts. These findings are among the first to document prevalence differences within the LGBQ population based on intersectional identities (race/ethnicity and religious affiliation). Providers should recognize that LGBQ individuals might need support in negotiating the complex relationship between multiple identities, especially due to their elevated prevalence of suicidal ideation. PMID:25795534

  2. Associations of racial/ethnic identities and religious affiliation with suicidal ideation among lesbian, gay, bisexual, and questioning individuals.

    PubMed

    Lytle, Megan C; De Luca, Susan M; Blosnich, John R; Brownson, Chris

    2015-06-01

    Our aim was to examine the associations of racial/ethnic identity and religious affiliation with suicidal ideation among lesbian, gay, bisexual, and questioning (LGBQ) and heterosexual college students. An additional aim was to determine the prevalence of passive suicidal ideation (i.e., death ideation) and active suicidal ideation among culturally diverse LGBQ individuals. Data from the National Research Consortium probability-based sample of college students from 70 postsecondary institutions (n=24,626) were used to examine active and passive suicidal ideation in the past 12-months and lifetime active suicidal ideation among students by sexual orientation, racial/ethnic identity, and religious affiliation. Across most racial/ethnic groups and religious affiliations, LGBQ students were more likely to report active suicidal ideation than non-LGBQ individuals. Among LGBQ students, Latino individuals had lower odds of reporting both past 12-month passive and active suicidal ideation than their non-Hispanic white LGBQ counterparts. Compared to Christian LGBQ students, Agnostic/Atheist LGBQ individuals had greater odds of reporting past 12-month passive suicidal ideation, and Jewish LGBQ students were less likely to endorse past 12-month passive and active suicidal ideation. Cross-sectional design and self-reported data. Results corroborate previous research showing elevated prevalence of suicidal ideation among LGBQ individuals in comparison to their heterosexual counterparts. These findings are among the first to document prevalence differences within the LGBQ population based on intersectional identities (race/ethnicity and religious affiliation). Providers should recognize that LGBQ individuals might need support in negotiating the complex relationship between multiple identities, especially due to their elevated prevalence of suicidal ideation. Copyright © 2015 Elsevier B.V. All rights reserved.

  3. Ethical consequences for professionals from the globalization of food, nutrition and health.

    PubMed

    Solomons, Noel W

    2002-01-01

    Globalization is the process of increasing interconnections and linkages, within societies and across geography, due to improved communication and expanded world trade. It limits the differentiation wrought by human cultural evolution, and homogenizes health practices, diet and lifestyle. There are both beneficial and adverse consequences of the globalization process. Globalization also presents a challenge to the development of ethics for practice and advocacy by food and nutrition professionals. Among the related terms, 'morals', 'values' and 'ethics', the latter connotes the basic rules of conduct for interactions within society and with the inanimate environment; rules based on recognized principles (ethical principles). The application of these principles is to resolve ethical dilemmas that arise when more than one interest is at play. Recognized ethical principles include autonomy, beneficence, non-maleficence, justice, utility and stewardship. These can be framed in the context of issues that arise during advocacy for material and behavioural changes to improve the nutritional health of populations. Clearly, at the global level, codes of good conduct and the construction of good food governance can be useful in institutionalizing ethical principles in matters of human diets and eating practices. Ethical dilemmas arise in the context of innate diversity among populations (some individuals benefit, whereas others suffer from the same exposures), and due to the polarity of human physiology and metabolism (practices that prevent some diseases will provoke other maladies). Moreover, the autonomy of one individual to exercise independent will in addressing personal health or treatment of the environment may compromise the health of the individual's neighbours. The challenges for the professional in pursuit of ethical advocacy in a globalized era are to learn the fundamentals of ethical principles; to bear in mind a respect for difference and differentiation that continues to exist, and which should exist, among individuals and societies; and to avoid a total homogenization of agriculture and food supplies.

  4. A Kinect-Based Sign Language Hand Gesture Recognition System for Hearing- and Speech-Impaired: A Pilot Study of Pakistani Sign Language.

    PubMed

    Halim, Zahid; Abbas, Ghulam

    2015-01-01

    Sign language provides hearing and speech impaired individuals with an interface to communicate with other members of the society. Unfortunately, sign language is not understood by most of the common people. For this, a gadget based on image processing and pattern recognition can provide with a vital aid for detecting and translating sign language into a vocal language. This work presents a system for detecting and understanding the sign language gestures by a custom built software tool and later translating the gesture into a vocal language. For the purpose of recognizing a particular gesture, the system employs a Dynamic Time Warping (DTW) algorithm and an off-the-shelf software tool is employed for vocal language generation. Microsoft(®) Kinect is the primary tool used to capture video stream of a user. The proposed method is capable of successfully detecting gestures stored in the dictionary with an accuracy of 91%. The proposed system has the ability to define and add custom made gestures. Based on an experiment in which 10 individuals with impairments used the system to communicate with 5 people with no disability, 87% agreed that the system was useful.

  5. Climate Leadership Awards Application Process, Eligibility, and Evaluation Criteria

    EPA Pesticide Factsheets

    Learn about evaluation criteria and access applications for the 2018 Climate Leadership Awards, which publicly recognizes individuals and organizations for their outstanding leadership in reducing greenhouse gas emissions.

  6. Climate Leadership Awards and Conference

    EPA Pesticide Factsheets

    The seventh annual Climate Leadership Awards Dinner will be held during the 2018 Climate Leadership Conference; the event publicly recognize individuals and organizations for their outstanding leadership in reducing greenhouse gas emissions.

  7. Imaging Management of Breast Density, a Controversial Risk Factor for Breast Cancer.

    PubMed

    Falcon, Shannon; Williams, Angela; Weinfurtner, Jared; Drukteinis, Jennifer S

    2017-04-01

    Breast density is well recognized as an independent risk factor for the development of breast cancer. However, the magnitude of risk is controversial. As the public becomes increasingly aware of breast density as a risk factor, legislation and notification laws in relation to breast density have become common throughout the United States. Awareness of breast density as a risk factor for breast cancer presents new challenges for the clinician in the approach to the management and screening of women with dense breasts. The evidence and controversy surrounding breast density as a risk factor for the development of breast cancer are discussed. Common supplemental screening modalities for breast cancer are also discussed, including tomosynthesis, ultrasonography, and magnetic resonance imaging. A management strategy for screening women with dense breasts is also presented. The American College of Radiology recognizes breast density as a controversial risk factor for breast cancer, whereas the American Congress of Obstetricians and Gynecologists recognizes breast density as a modest risk factor. Neither organization recommends the routine use of supplemental screening in women with dense breasts without considering additional patient-related risk factors. Breast density is a poorly understood and controversial risk factor for the development of breast cancer. Mammography is a screening modality proven to reduce breast cancer-related mortality rates and is the single most appropriate tool for population-based screening. Use of supplemental screening modalities should be tailored to individual risk assessment.

  8. Tailoring hospital marketing efforts to physicians' needs.

    PubMed

    Mackay, J M; Lamb, C W

    1988-12-01

    Marketing has become widely recognized as an important component of hospital management (Kotler and Clarke 1987; Ludke, Curry, and Saywell 1983). Physicians are becoming recognized as an important target market that warrants more marketing attention than it has received in the past (Super 1987; Wotruba, Haas, and Hartman 1982). Some experts predict that hospitals will begin focusing more marketing attention on physicians and less on consumers (Super 1986). Much of this attention is likely to take the form of practice management assistance, such as computer-based information system support or consulting services. The survey results reported here are illustrative only of how one hospital addressed the problem of physician need assessment. Other potential target markets include physicians who admit patients only to competitor hospitals and physicians who admit to multiple hospitals. The market might be segmented by individual versus group practice, area of specialization, or possibly even physician practice life cycle stage (Wotruba, Haas, and Hartman 1982). The questions included on the survey and the survey format are likely to be situation-specific. The key is the process, not the procedure. It is important for hospital marketers to recognize that practice management assistance needs will vary among markets (Jensen 1987). Therefore, hospitals must carefully identify their target physician market(s) and survey them about their specific needs before developing and implementing new physician marketing programs. Only then can they be reasonably confident that their marketing programs match their customers' needs.

  9. Disorders of Sex Development (DSD): Networking and Standardization Considerations.

    PubMed

    Sandberg, D E; Callens, N; Wisniewski, A B

    2015-05-01

    Syndromes resulting in Disorders of Sex Development (DSD) are individually rare. Historically, this fact has hindered both clinical research and the delivery of evidence-based care. Recognizing the need for advancement, members of European and North American medical societies produced policy statements, notably the Consensus Statement on Management of Intersex Disorders, which recognize that optimal healthcare in DSD requires multidisciplinary teams in conjunction with networking of treatment centers and continued development of patient registries. This paper summarizes efforts in Europe and the U.S. toward creating networks focused on expanding discovery and improving healthcare and quality of life outcomes in DSD. The objectives and function of registry-based networks (EuroDSD/I-DSD), learning collaboratives (DSD-net), clinical outcomes research (DSD-Life), and networking hybrids (DSD-TRN) are reviewed. Opportunities for, and barriers to standardization in research and care are highlighted in light of practical considerations, for example, limitations in reliably classifying anatomic phenotypes and gaps in behavioral health staffing resources. The role of patient-reported outcomes is considered, with emphasis on integrating patient perspectives, given findings of limited agreement in outcome ratings by healthcare providers and patients. Finally, the characteristics of clinical centers likely to deliver the highest quality outcomes are discussed. © Georg Thieme Verlag KG Stuttgart · New York.

  10. The Common Prescription Patterns Based on the Hierarchical Clustering of Herb-Pairs Efficacies

    PubMed Central

    2016-01-01

    Prescription patterns are rules or regularities used to generate, recognize, or judge a prescription. Most of existing studies focused on the specific prescription patterns for diverse diseases or syndromes, while little attention was paid to the common patterns, which reflect the global view of the regularities of prescriptions. In this paper, we designed a method CPPM to find the common prescription patterns. The CPPM is based on the hierarchical clustering of herb-pair efficacies (HPEs). Firstly, HPEs were hierarchically clustered; secondly, the individual herbs are labeled by the HPEC (the clusters of HPEs); and then the prescription patterns were extracted from the combinations of HPEC; finally the common patterns are recognized statistically. The results showed that HPEs have hierarchical clustering structure. When the clustering level is 2 and the HPEs were classified into two clusters, the common prescription patterns are obvious. Among 332 candidate prescriptions, 319 prescriptions follow the common patterns. The description of the patterns is that if a prescription contains the herbs of the cluster (C 1), it is very likely to have other herbs of another cluster (C 2); while a prescription has the herbs of C 2, it may have no herbs of C 1. Finally, we discussed that the common patterns are mathematically coincident with the Blood-Qi theory. PMID:27190534

  11. Occupational Therapy Students' Perceptions of Spirituality in Training.

    PubMed

    Mthembu, Thuli Godfrey; Ahmed, Firdous; Nkuna, Thembi; Yaca, Khalipha

    2015-12-01

    Spirituality is recognized as an essential and integral component of a holistic approach in occupational therapy practice. However, little is known about occupational therapy students' perceptions regarding spirituality in learning context. This study used qualitative exploratory, descriptive design to explore the occupational therapy students' perceptions about spirituality in training. Using purposive sampling, four semi-structured interviews were conducted with two students, a lecturer and an occupational therapist. In addition, two focus groups were conducted with students in order to collect data. Data collected were audio-taped; transcribed and thematic analysis was used to identify themes. The analysis resulted in emergence of four themes: "Unique to every individual," "Spirituality in occupational therapy," "To be or not to be taught," and "The Real world." Participants perceived spirituality as an individually experienced. The study contributes to the body of knowledge base of occupational therapy education regarding spirituality. However, there is a need for guidelines to integrate spirituality in occupational therapy training.

  12. Tooth enamel dosimetric response to 2.8 MeV neutrons

    NASA Astrophysics Data System (ADS)

    Fattibene, P.; Angelone, M.; Pillon, M.; De Coste, V.

    2003-03-01

    Tooth enamel dosimetry, based on electron paramagnetic resonance (EPR) spectroscopy, is recognized as a powerful method for individual retrospective dose assessment. The method is mainly used for individual dose reconstruction in the epidemiological studies aimed at the radiation risk analysis. The study of the sensitivity of tooth enamel as a function of radiation quality is one of the main goals of the research in this field. In the present work, tooth enamel dose response in a monoenergetic neutron flux of 2.8 MeV, generated by the D-D reaction, was studied for in air and in phantom irradiations of enamel samples and of whole teeth. EPR measurements were complemented by Monte Carlo calculation and by gamma dose discrimination obtained with thermoluminescent and Geiger-Muller tube measurements. The 2.8 MeV neutrons to 60Co relative sensitivity was 0.33±0.08.

  13. PTSD blogs.

    PubMed

    Ramanathan, Vaidehi

    2015-01-01

    This paper addresses issues around the automatic repetition of particular memories in the narratives / blog accounts of individuals with Post Traumatic Stress Disorder (PTSD). Based on a long-term project that examines how people with various body-related conditions and ailments write or speak about their bodies, the focus of this paper is on 80 blog accounts wherein individuals with PTSD write both about living with the condition and about their steps towards healing themselves. The paper pays special attention to how the act of repeated blogging counters the paralyzing repetition in their heads, leading them to re-cognize particular distressing life-events and thus creating alternate episodic structures (Gee 1992). In particular, the article addresses: What insights about repetition and memory are we able to glean from PTSD pathographies, and in what ways does current scholarship in narrative analysis, applied sociolinguistics, and psychology permit a more complex understanding of the condition?

  14. The effects of moral judgment and moral identity on moral behavior: an empirical examination of the moral individual.

    PubMed

    Reynolds, Scott J; Ceranic, Tara L

    2007-11-01

    Recognizing limitations in classic cognitive moral development theory, several scholars have drawn from theories of identity to suggest that moral behavior results from both moral judgments and moral identity. The authors conducted 2 survey-based studies with more than 500 students and managers to test this argument. Results demonstrated that moral identity and moral judgments both independently influenced moral behavior. In addition, in situations in which social consensus regarding the moral behavior was not high, moral judgments and moral identity interacted to shape moral behavior. This interaction effect indicated that those who viewed themselves as moral individuals pursued the most extreme alternatives (e.g., never cheating, regularly cheating)--a finding that affirms the motivational power of a moral identity. The authors conclude by considering the implications of this research for both theory and practice. (c) 2007 APA

  15. Siblings of individuals with first-episode psychosis: understanding their experiences and needs.

    PubMed

    Sin, Jacqueline; Moone, Nicki; Harris, Paul

    2008-06-01

    The growth of early intervention in psychosis services (EIPS) has prompted needed research to provide a robust evidence base to underpin practice. The typical service model embraces key psychosocial interventions, including family interventions. A literature review revealed a number of relevant studies that recognized the role of siblings in families affected by severe mental illness or mental impairment, but little was found about the impact of first-episode psychosis on siblings. To address this apparent oversight, we conducted a study to gain an understanding of sibling experiences. Ten siblings (ages 16 to 30) with a brother or sister diagnosed with first-episode psychosis took part in individual semi-structured interviews. The key findings were grouped in regard to emotional impact, relationships in the family, and siblings' roles and coping patterns. The study also revealed that families are able to identify positive gains out of a fundamentally negative experience.

  16. Individual muscle segmentation in MR images: A 3D propagation through 2D non-linear registration approaches.

    PubMed

    Ogier, Augustin; Sdika, Michael; Foure, Alexandre; Le Troter, Arnaud; Bendahan, David

    2017-07-01

    Manual and automated segmentation of individual muscles in magnetic resonance images have been recognized as challenging given the high variability of shapes between muscles and subjects and the discontinuity or lack of visible boundaries between muscles. In the present study, we proposed an original algorithm allowing a semi-automatic transversal propagation of manually-drawn masks. Our strategy was based on several ascending and descending non-linear registration approaches which is similar to the estimation of a Lagrangian trajectory applied to manual masks. Using several manually-segmented slices, we have evaluated our algorithm on the four muscles of the quadriceps femoris group. We mainly showed that our 3D propagated segmentation was very accurate with an averaged Dice similarity coefficient value higher than 0.91 for the minimal manual input of only two manually-segmented slices.

  17. 2017 Outstanding Contributions to ISCB Award: Fran Lewitter.

    PubMed

    Fogg, Christiana N; Kovats, Diane E; Berger, Bonnie

    2017-01-01

    The Outstanding Contributions to the International Society for Computational Biology (ISCB) Award was launched in 2015 to recognize individuals who have made lasting and valuable contributions to the Society through their leadership, service, and educational work, or a combination of these areas. Fran Lewitter is the 2017 winner of the Outstanding Contributions to ISCB Award and will be recognized at the 2017 Intelligent Systems for Molecular Biology (ISMB)/European Conference on Computational Biology, meeting in Prague, Czech Republic being held from July 21-25, 2017.

  18. 2017 Outstanding Contributions to ISCB Award: Fran Lewitter

    PubMed Central

    Fogg, Christiana N.; Kovats, Diane E.; Berger, Bonnie

    2017-01-01

    The Outstanding Contributions to the International Society for Computational Biology (ISCB) Award was launched in 2015 to recognize individuals who have made lasting and valuable contributions to the Society through their leadership, service, and educational work, or a combination of these areas. Fran Lewitter is the 2017 winner of the Outstanding Contributions to ISCB Award and will be recognized at the 2017 Intelligent Systems for Molecular Biology (ISMB)/European Conference on Computational Biology, meeting in Prague, Czech Republic being held from July 21-25, 2017. PMID:28713545

  19. The role of external features in face recognition with central vision loss: A pilot study

    PubMed Central

    Bernard, Jean-Baptiste; Chung, Susana T.L.

    2016-01-01

    Purpose We evaluated how the performance for recognizing familiar face images depends on the internal (eyebrows, eyes, nose, mouth) and external face features (chin, outline of face, hairline) in individuals with central vision loss. Methods In Experiment 1, we measured eye movements for four observers with central vision loss to determine whether they fixated more often on the internal or the external features of face images while attempting to recognize the images. We then measured the accuracy for recognizing face images that contained only the internal, only the external, or both internal and external features (Experiment 2), and for hybrid images where the internal and external features came from two different source images (Experiment 3), for five observers with central vision loss and four age-matched control observers. Results When recognizing familiar face images, approximately 40% of the fixations of observers with central vision loss were centered on the external features of faces. The recognition accuracy was higher for images containing only external features (66.8±3.3% correct) than for images containing only internal features (35.8±15.0%), a finding contradicting that of control observers. For hybrid face images, observers with central vision loss responded more accurately to the external features (50.4±17.8%) than to the internal features (9.3±4.9%), while control observers did not show the same bias toward responding to the external features. Conclusions Contrary to people with normal vision who rely more on the internal features of face images for recognizing familiar faces, individuals with central vision loss show a higher dependence on using external features of face images. PMID:26829260

  20. Recognized focused practice: Does sub-specialty designation offer value to the neurosurgeon?

    PubMed

    Babu, Maya A; Liau, Linda M; Meyer, Fredric B

    2017-01-01

    Vehicles for life-long assessment such as Maintenance of Certification tend to focus on generalist neurosurgical knowledge. However, as neurosurgeons advance in their careers, they tend to narrow their practice and increase volumes in certain specific types of operations. Failing to test the type of procedures most relevant to the practitioner is a lost opportunity to improve the knowledge and practice of the individual neurosurgeon. In this study, we assess the neurosurgical community's appetite for designations of board-recognized Recognized Focused Practice (RFP). We administered a validated, online, confidential survey to 4,899 neurosurgeons (2,435 American Board of Neurological Surgery (ABNS) Diplomates participating in MOC, 1,440 Diplomates certified prior to 1999 (grandfathered), and 1,024 retired Diplomates). We received 1,449 responses overall (30% response rate). A plurality of respondents were in practice 11-15 years (18.5%), in private practice (40%) and participate in MOC (61%). 49% of respondents felt that a RFP designation would not be helpful. For the 30% who felt that RFP would be helpful, 61.3% felt that it would support recognition by their hospital or practice, it would motivate them to stay current on medical knowledge (53.4%), or it would help attract patients (46.4%;). The most popular suggestions for RFP were Spine (56.2%), Cerebrovascular (62.9%), Pediatrics (64.1%), and Functional/Stereotactic (52%). A plurality of neurosurgeons (35.7%) felt that RFP should recognize neurosurgeons with accredited and non-accredited fellowship experience and sub-specialty experience. Ultimately, Recognized Focused Practice may provide value to individual neurosurgeons, but the neurosurgical community shows tepid interest for pursuing this designation.

  1. Recognized focused practice: Does sub-specialty designation offer value to the neurosurgeon?

    PubMed Central

    Liau, Linda M.; Meyer, Fredric B.

    2017-01-01

    Vehicles for life-long assessment such as Maintenance of Certification tend to focus on generalist neurosurgical knowledge. However, as neurosurgeons advance in their careers, they tend to narrow their practice and increase volumes in certain specific types of operations. Failing to test the type of procedures most relevant to the practitioner is a lost opportunity to improve the knowledge and practice of the individual neurosurgeon. In this study, we assess the neurosurgical community’s appetite for designations of board-recognized Recognized Focused Practice (RFP). We administered a validated, online, confidential survey to 4,899 neurosurgeons (2,435 American Board of Neurological Surgery (ABNS) Diplomates participating in MOC, 1,440 Diplomates certified prior to 1999 (grandfathered), and 1,024 retired Diplomates). We received 1,449 responses overall (30% response rate). A plurality of respondents were in practice 11–15 years (18.5%), in private practice (40%) and participate in MOC (61%). 49% of respondents felt that a RFP designation would not be helpful. For the 30% who felt that RFP would be helpful, 61.3% felt that it would support recognition by their hospital or practice, it would motivate them to stay current on medical knowledge (53.4%), or it would help attract patients (46.4%;). The most popular suggestions for RFP were Spine (56.2%), Cerebrovascular (62.9%), Pediatrics (64.1%), and Functional/Stereotactic (52%). A plurality of neurosurgeons (35.7%) felt that RFP should recognize neurosurgeons with accredited and non-accredited fellowship experience and sub-specialty experience. Ultimately, Recognized Focused Practice may provide value to individual neurosurgeons, but the neurosurgical community shows tepid interest for pursuing this designation. PMID:29240838

  2. Immunodominant epitopes in herpes simplex virus type 2 glycoprotein D are recognized by CD4 lymphocytes from both HSV-1 and HSV-2 seropositive subjects.

    PubMed

    Kim, Min; Taylor, Janette; Sidney, John; Mikloska, Zorka; Bodsworth, Neil; Lagios, Katerina; Dunckley, Heather; Byth-Wilson, Karen; Denis, Martine; Finlayson, Robert; Khanna, Rajiv; Sette, Alessandro; Cunningham, Anthony L

    2008-11-01

    In human recurrent cutaneous herpes simplex, there is a sequential infiltrate of CD4 and then CD8 lymphocytes into lesions. CD4 lymphocytes are the major producers of the key cytokine IFN-gamma in lesions. They recognize mainly structural proteins and especially glycoproteins D and B (gD and gB) when restimulated in vitro. Recent human vaccine trials using recombinant gD showed partial protection of HSV seronegative women against genital herpes disease and also, in placebo recipients, showed protection by prior HSV1 infection. In this study, we have defined immunodominant peptide epitopes recognized by 8 HSV1(+) and/or 16 HSV2(+) patients using (51)Cr-release cytotoxicity and IFN-gamma ELISPOT assays. Using a set of 39 overlapping 20-mer peptides, more than six immunodominant epitopes were defined in gD2 (two to six peptide epitopes were recognized for each subject). Further fine mapping of these responses for 4 of the 20-mers, using a panel of 9 internal 12-mers for each 20-mers, combined with MHC II typing and also direct in vitro binding assay of these peptides to individual DR molecules, showed more than one epitope per 20-mers and promiscuous binding of individual 20-mers and 12-mers to multiple DR types. All four 20-mer peptides were cross-recognized by both HSV1(+)/HSV2(-) and HSV1(-)/HSV2(+) subjects, but the sites of recognition differed within the 20-mers where their sequences were divergent. This work provides a basis for CD4 lymphocyte cross-recognition of gD2 and possibly cross-protection observed in previous clinical studies and in vaccine trials.

  3. The Role of External Features in Face Recognition with Central Vision Loss.

    PubMed

    Bernard, Jean-Baptiste; Chung, Susana T L

    2016-05-01

    We evaluated how the performance of recognizing familiar face images depends on the internal (eyebrows, eyes, nose, mouth) and external face features (chin, outline of face, hairline) in individuals with central vision loss. In experiment 1, we measured eye movements for four observers with central vision loss to determine whether they fixated more often on the internal or the external features of face images while attempting to recognize the images. We then measured the accuracy for recognizing face images that contained only the internal, only the external, or both internal and external features (experiment 2) and for hybrid images where the internal and external features came from two different source images (experiment 3) for five observers with central vision loss and four age-matched control observers. When recognizing familiar face images, approximately 40% of the fixations of observers with central vision loss was centered on the external features of faces. The recognition accuracy was higher for images containing only external features (66.8 ± 3.3% correct) than for images containing only internal features (35.8 ± 15.0%), a finding contradicting that of control observers. For hybrid face images, observers with central vision loss responded more accurately to the external features (50.4 ± 17.8%) than to the internal features (9.3 ± 4.9%), whereas control observers did not show the same bias toward responding to the external features. Contrary to people with normal vision who rely more on the internal features of face images for recognizing familiar faces, individuals with central vision loss show a higher dependence on using external features of face images.

  4. Controlling nosocomial infection based on structure of hospital social networks.

    PubMed

    Ueno, Taro; Masuda, Naoki

    2008-10-07

    Nosocomial infection (i.e. infection in healthcare facilities) raises a serious public health problem, as implied by the existence of pathogens characteristic to healthcare facilities such as methicillin-resistant Staphylococcus aureus and hospital-mediated outbreaks of influenza and severe acute respiratory syndrome. For general communities, epidemic modeling based on social networks is being recognized as a useful tool. However, disease propagation may occur in a healthcare facility in a manner different from that in a urban community setting due to different network architecture. We simulate stochastic susceptible-infected-recovered dynamics on social networks, which are based on observations in a hospital in Tokyo, to explore effective containment strategies against nosocomial infection. The observed social networks in the hospital have hierarchical and modular structure in which dense substructure such as departments, wards, and rooms, are globally but only loosely connected, and do not reveal extremely right-skewed distributions of the number of contacts per individual. We show that healthcare workers, particularly medical doctors, are main vectors (i.e. transmitters) of diseases on these networks. Intervention methods that restrict interaction between medical doctors and their visits to different wards shrink the final epidemic size more than intervention methods that directly protect patients, such as isolating patients in single rooms. By the same token, vaccinating doctors with priority rather than patients or nurses is more effective. Finally, vaccinating individuals with large betweenness centrality (frequency of mediating connection between pairs of individuals along the shortest paths) is superior to vaccinating ones with large connectedness to others or randomly chosen individuals, which was suggested by previous model studies.

  5. Effectiveness of repeated examination to diagnose enterobiasis in nursery school groups.

    PubMed

    Remm, Mare; Remm, Kalle

    2009-09-01

    The aim of this study was to estimate the benefit from repeated examinations in the diagnosis of enterobiasis in nursery school groups, and to test the effectiveness of individual-based risk predictions using different methods. A total of 604 children were examined using double, and 96 using triple, anal swab examinations. The questionnaires for parents, structured observations, and interviews with supervisors were used to identify factors of possible infection risk. In order to model the risk of enterobiasis at individual level, a similarity-based machine learning and prediction software Constud was compared with data mining methods in the Statistica 8 Data Miner software package. Prevalence according to a single examination was 22.5%; the increase as a result of double examinations was 8.2%. Single swabs resulted in an estimated prevalence of 20.1% among children examined 3 times; double swabs increased this by 10.1%, and triple swabs by 7.3%. Random forest classification, boosting classification trees, and Constud correctly predicted about 2/3 of the results of the second examination. Constud estimated a mean prevalence of 31.5% in groups. Constud was able to yield the highest overall fit of individual-based predictions while boosting classification tree and random forest models were more effective in recognizing Enterobius positive persons. As a rule, the actual prevalence of enterobiasis is higher than indicated by a single examination. We suggest using either the values of the mean increase in prevalence after double examinations compared to single examinations or group estimations deduced from individual-level modelled risk predictions.

  6. Effectiveness of Repeated Examination to Diagnose Enterobiasis in Nursery School Groups

    PubMed Central

    Remm, Kalle

    2009-01-01

    The aim of this study was to estimate the benefit from repeated examinations in the diagnosis of enterobiasis in nursery school groups, and to test the effectiveness of individual-based risk predictions using different methods. A total of 604 children were examined using double, and 96 using triple, anal swab examinations. The questionnaires for parents, structured observations, and interviews with supervisors were used to identify factors of possible infection risk. In order to model the risk of enterobiasis at individual level, a similarity-based machine learning and prediction software Constud was compared with data mining methods in the Statistica 8 Data Miner software package. Prevalence according to a single examination was 22.5%; the increase as a result of double examinations was 8.2%. Single swabs resulted in an estimated prevalence of 20.1% among children examined 3 times; double swabs increased this by 10.1%, and triple swabs by 7.3%. Random forest classification, boosting classification trees, and Constud correctly predicted about 2/3 of the results of the second examination. Constud estimated a mean prevalence of 31.5% in groups. Constud was able to yield the highest overall fit of individual-based predictions while boosting classification tree and random forest models were more effective in recognizing Enterobius positive persons. As a rule, the actual prevalence of enterobiasis is higher than indicated by a single examination. We suggest using either the values of the mean increase in prevalence after double examinations compared to single examinations or group estimations deduced from individual-level modelled risk predictions. PMID:19724696

  7. Identifying DNA Methylation Biomarkers for Non-Endoscopic Detection of Barrett’s Esophagus

    PubMed Central

    Moinova, Helen R.; LaFramboise, Thomas; Lutterbaugh, James D.; Chandar, Apoorva Krishna; Dumot, John; Faulx, Ashley; Brock, Wendy; De la Cruz Cabrera, Omar; Guda, Kishore; Barnholtz-Sloan, Jill S.; Iyer, Prasad G.; Canto, Marcia I.; Wang, Jean S.; Shaheen, Nicholas J.; Thota, Prashanti N.; Willis, Joseph E.; Chak, Amitabh; Markowitz, Sanford D.

    2018-01-01

    We report a biomarker-based non-endoscopic method for detecting Barrett’s esophagus (BE), based on detecting methylated DNAs retrieved via a swallowable balloon-based esophageal sampling device. BE is the precursor of, and a major recognized risk factor for, developing esophageal adenocarcinoma (EAC). Endoscopy, the current standard for BE detection, is not cost-effective for population screening. We performed genome-wide screening to ascertain regions targeted for recurrent aberrant cytosine methylation in BE, identifying high-frequency methylation within the CCNA1 locus. We tested CCNA1 DNA methylation as a BE biomarker in cytology brushings of the distal esophagus from 173 individuals with or without BE. CCNA1 DNA methylation demonstrated an area under the curve (AUC)=0.95 for discriminating BE-related metaplasia and neoplasia cases versus normal individuals, performing identically to methylation of VIM DNA, an established BE biomarker. When combined, the resulting two biomarker panel was 95% sensitive and 91% specific. These results were replicated in an independent validation cohort of 149 individuals, who were assayed using the same cutoff values for test positivity established in the training population. To progress toward non-endoscopic esophageal screening, we engineered a well-tolerated, swallowable, encapsulated balloon device able to selectively sample the distal esophagus within 5 minutes. In balloon samples from 86 individuals, tests of CCNA1 plus VIM DNA methylation detected BE metaplasia with 90.3% sensitivity and 91.7% specificity. Combining the balloon sampling device with molecular assays of CCNA1 plus VIM DNA methylation enables an efficient, well-tolerated, sensitive, and specific method of screening at-risk populations for BE. PMID:29343623

  8. Social implications arise in embodied music cognition research which can counter musicological "individualism".

    PubMed

    Moran, Nikki

    2014-01-01

    The agenda in music research that is broadly recognized as embodied music cognition has arrived hand-in-hand with a social interpretation of music, focusing on the real-world basis of its performance, and fostering an empirical approach to musician movement regarding the communicative function and potential of those movements. However, embodied cognition emerged from traditional cognitivism, which produced a body of scientific explanation of music-theoretic concepts. The analytical object of this corpus is based on the particular imagined encounter of a listener responding to an idealized "work." Although this problem of essentialism has been identified within mainstream musicology, the lingering effects may spill over into interdisciplinary, empirical research. This paper defines the situation according to its legacy of individualism, and offers an alternative sketch of musical activity as performance event, a model that highlights the social interaction processes at the heart of musical behavior. I describe some recent empirical work based on interaction-oriented approaches, arguing that this particular focus - on the social interaction process itself - creates a distinctive and promising agenda for further research into embodied music cognition.

  9. The Multifold Relationship Between Memory and Decision Making: An Individual-differences Study

    PubMed Central

    Del Missier, Fabio; Mäntylä, Timo; Hansson, Patrik; Bruine de Bruin, Wändi; Parker, Andrew M.; Nilsson, Lars-Göran

    2014-01-01

    Several judgment and decision-making tasks are assumed to involve memory functions, but significant knowledge gaps on the memory processes underlying these tasks remain. In a study on 568 adults between 25 to 80 years, hypotheses were tested on the specific relationships between individual differences in working memory, episodic memory, and semantic memory, respectively, and six main components of decision-making competence. In line with the hypotheses, working memory was positively related with the more cognitively-demanding tasks (Resistance to Framing, Applying Decision Rules, and Under/Overconfidence), whereas episodic memory was positively associated with a more experience-based judgment task (Recognizing Social Norms). Furthermore, semantic memory was positively related with two more knowledge-based decision-making tasks (Consistency in Risk Perception and Resistance to Sunk Costs). Finally, the age-related decline observed in some of the decision-making tasks was (partially or totally) mediated by the age-related decline in working memory or episodic memory. These findings are discussed in relation to the functional roles fulfilled by different memory processes in judgment and decision-making tasks. PMID:23565790

  10. Recurring patterns in the songs of humpback whales (Megaptera novaeangliae).

    PubMed

    Green, Sean R; Mercado, Eduardo; Pack, Adam A; Herman, Louis M

    2011-02-01

    Humpback whales, unlike most mammalian species, learn new songs as adults. Populations of singers progressively and collectively change the sounds and patterns within their songs throughout their lives and across generations. In this study, humpback whale songs recorded in Hawaii from 1985 to 1995 were analyzed using self-organizing maps (SOMs) to classify the sounds within songs, and to identify sound patterns that were present across multiple years. These analyses supported the hypothesis that recurring, persistent patterns exist within whale songs, and that these patterns are defined at least in part by acoustic relationships between adjacent sounds within songs. Sound classification based on acoustic differences between adjacent sounds yielded patterns within songs that were more consistent from year to year than classifications based on the properties of single sounds. Maintenance of fixed ratios of acoustic modulation across sounds, despite large variations in individual sounds, suggests intrinsic constraints on how sounds change within songs. Such acoustically invariant cues may enable whales to recognize and assess variations in songs despite propagation-related distortion of individual sounds and yearly changes in songs. Copyright © 2011 Elsevier B.V. All rights reserved.

  11. Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes.

    PubMed

    Bentzen, Amalie Kai; Marquard, Andrea Marion; Lyngaa, Rikke; Saini, Sunil Kumar; Ramskov, Sofie; Donia, Marco; Such, Lina; Furness, Andrew J S; McGranahan, Nicholas; Rosenthal, Rachel; Straten, Per Thor; Szallasi, Zoltan; Svane, Inge Marie; Swanton, Charles; Quezada, Sergio A; Jakobsen, Søren Nyboe; Eklund, Aron Charles; Hadrup, Sine Reker

    2016-10-01

    Identification of the peptides recognized by individual T cells is important for understanding and treating immune-related diseases. Current cytometry-based approaches are limited to the simultaneous screening of 10-100 distinct T-cell specificities in one sample. Here we use peptide-major histocompatibility complex (MHC) multimers labeled with individual DNA barcodes to screen >1,000 peptide specificities in a single sample, and detect low-frequency CD8 T cells specific for virus- or cancer-restricted antigens. When analyzing T-cell recognition of shared melanoma antigens before and after adoptive cell therapy in melanoma patients, we observe a greater number of melanoma-specific T-cell populations compared with cytometry-based approaches. Furthermore, we detect neoepitope-specific T cells in tumor-infiltrating lymphocytes and peripheral blood from patients with non-small cell lung cancer. Barcode-labeled pMHC multimers enable the combination of functional T-cell analysis with large-scale epitope recognition profiling for the characterization of T-cell recognition in various diseases, including in small clinical samples.

  12. Getting from here to there: health IT needs for population health.

    PubMed

    Vest, Joshua R; Harle, Christopher A; Schleyer, Titus; Dixon, Brian E; Grannis, Shaun J; Halverson, Paul K; Menachemi, Nir

    2016-12-01

    The United States' decade-long transition from a paper- to technology-based information infrastructure has always been recognized as an initial step-a laying of the foundation-for future changes to the delivery of care. An increasingly important focal area for improvement is population health. Numerous policies and programs now require healthcare organizations to manage the risks, outcomes, utilization, and health of entire groups of individuals. Nonetheless, current health information technology (IT) systems are not ready to support population health improvements effectively and efficiently. Existing health IT systems were designed for organizations that are structurally, operationally, and culturally focused on individual care delivery, rather than improving health for a population. Opportunities exist to align health IT resources and population health management strategies to fill the gaps among technological capabilities, use and the emerging demands of population health. To realize this alignment, healthcare leaders must think differently about the types of data their organizations need, the types of partners with whom they share information, and how they can leverage new information and partnerships for evidence-based action.

  13. Challenges of regulatory rights of half-capacitated persons: A sociological perspective on the French Civil Code reform.

    PubMed

    Eyraud, Benoît

    2016-01-01

    Democratic societies are based on the principle of equal legal capacity of all citizens to decide and act for themselves in all areas of social life. This "socio-civil capacity", which may involve both material property of an individual, as well as private life in matters ranging from health to personal relationships, is recognized by the law (both codified law and common law). These rights guarantee the autonomy and freedom of individuals in the name of respect for human dignity. Civil capacity of a person is legally diminished because his or her "natural" abilities, capacity, or competence are reduced. Recent social changes have lead to increased uses of legal measures of protection. The reasons for these changes are complex and they are accompanied by legislative reforms that modify the rights of half-capacitated persons. In this article, we examine certain issues of civil capacity rights based on the French example. We start present a perspective of the historical definition and practice of these rights as well as their democratization. Copyright © 2016. Published by Elsevier Ltd.

  14. Visuo-spatial knowledge acquisition in individuals with Down syndrome: The role of descriptions and sketch maps.

    PubMed

    Meneghetti, Chiara; Lanfranchi, Silvia; Carretti, Barbara; Toffalini, Enrico

    2017-04-01

    Few studies on individuals with Down syndrome (DS) have explored how they learn space. The present study examines space learning from verbal descriptions in individuals with DS, and explores the role of external cues (such as a sketch map). Twenty-eight individuals with DS and 28 matched typically-developing (TD) children listened to route or survey descriptions with or without seeing a corresponding sketch map (Description+Sketch Map [D+SM] and Description alone [D], respectively). After hearing each description, they performed tasks that involved recognizing, arranging sequentially, and locating landmarks. The results showed that individuals with DS performed less well in recognizing landmarks and arranging them sequentially. The D+SM condition produced general benefits in both groups' accuracy, though the improvement in locating landmarks was greater in the TD than in the DS group. In both groups, the D+SM condition prompted a better performance than the D condition when participants arranged landmarks sequentially after hearing a description from a route perspective, but not from a survey perspective. Overall, our results show that individuals with DS benefited when a spatial description was associated with a corresponding sketch map, albeit to a lesser degree than TD children. The findings are discussed in the light of the literature on DS and on spatial cognition in the TD domain. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Community as Locus for Health Formal and Non-Formal Education: The Significance of Ecological and Collaborative Research for Promoting Health Literacy

    PubMed Central

    Pais, Sofia C.; Rodrigues, Mariana; Menezes, Isabel

    2014-01-01

    The World Health Organization (2002) considers that a balance between government, community, and individual action is necessary for health education and promotion, recognizing that non-governmental organizations, local groups, and community institutions are central in this process. This argument reinforces the idea that individuals should be empowered and encouraged to make use of accurate health-related information. This paper highlights the potential of a socio-political perspective for the development of health literacy within children and adolescents and presents two studies conducted in two daily life contexts: a community organization and a school. Both studies are based on methodological pluralism and collaborative research approaches and explore the promotion of health knowledge in formal and informal settings. Study 1 is based on a mixed methodology, using focus group discussions and questionnaires with children and youth with chronic diseases to explore the perceived impact of their participation in support associations. Study 2 presents four intensive case-studies in schools where adolescents used community profiling, a participatory research methodology, to explore health rights and access to healthcare in both a historical and prospective vision. The results enable a deeper understanding on how powerful tool ccommunity resources can be for individual and collective empowerment on health issues. PMID:25566525

  16. A manual-based individual therapy to improve metacognition in schizophrenia: protocol of a multi-center RCT

    PubMed Central

    2014-01-01

    Background Metacognitive dysfunction has been widely recognized as a feature of schizophrenia. As it is linked with deficits in several aspects of daily life functioning, improvement of metacognition may lead to improvement in functioning. Individual psychotherapy might be a useful form of treatment to improve metacognition in patients with schizophrenia; multiple case reports and a pilot study show promising results. The present study aims to measure the effectiveness of an individual, manual-based therapy (Metacognitive Reflection and Insight Therapy, MERIT) in improving metacognition in patients with schizophrenia. We also want to examine if improvement in metacognitive abilities is correlated with improvements in aspects of daily life functioning namely social functioning, experience of symptoms, quality of life, depression, work readiness, insight and experience of stigma. Methods/Design MERIT is currently evaluated in a multicenter randomized controlled trial. Thirteen therapists in six mental health institutions in the Netherlands participate in this study. Patients are randomly assigned to either MERIT or the control condition: treatment as usual (TAU). Discussion If proven effective, MERIT can be a useful addition to the care for schizophrenia patients. The design brings along some methodological difficulties, these issues are addressed in the discussion of this paper. Trial registration Current Controlled Trials: ISRCTN16659871. PMID:24490942

  17. [Interprofessional symptom management at the end of life].

    PubMed

    Frankenhauser, S; Geist, M J P; Weigand, M A; Bardenheuer, H J; Keßler, J

    2018-05-01

    At the end of life patients often show distressful symptoms which significantly reduce their quality of life. The goal of all healthcare professionals should be to recognize the beginning of this end of life period in order to provide good symptom management. For this purpose, existing symptoms have to be recorded, suitable therapeutic goals have to be defined for the current situation and potential therapeutic strategies have to be individually formulated. Besides the identification of underlying causes with the possibility of causal treatment, a symptom-based therapy is often necessary. Therapeutic approaches of different professions should be equally considered and should additionally be used for the benefit of the patient.

  18. Method for traffic-sign detection within a picture by color identification and external shape recognition

    NASA Astrophysics Data System (ADS)

    Falcoff, Daniel E.; Canali, Luis R.

    1999-08-01

    This work present one method aimed to individualization and recognition of vial signs in route and city. It is based fundamentally on the identification by means of color and form of the vial sing, located in the border of the route or street in city, and then recognition. To do so the obtained RGB image is processed, carrying out diverse filtrates in the sequence of input image, or intensifying the colors of the same ones otherwise, recognizing their silhouette and then segmenting the sign and comparing the symbology of them with the previously stored and classified database.

  19. Linkage strategies for successful and sustainable partnerships: a practical framework for community engagement by palliative care services.

    PubMed

    Rosenberg, John

    2018-01-01

    Partnerships are central to the success of linkages between palliative care services and the communities they support. The goal of partnership is to achieve more than individuals and groups can achieve on their own, yet the concept is often poorly understood. A clearly articulated understanding of partnership is a powerful step in transforming an organization's engagement with the community. The aim of this workshop is to enable participants to gain a clear understanding of partnership, understand the recognized evidence-based principles of establishing and maintaining partnerships, and identify practical approaches to partnering to take back to their organizations and communities.

  20. How does the brain solve visual object recognition?

    PubMed Central

    Zoccolan, Davide; Rust, Nicole C.

    2012-01-01

    Mounting evidence suggests that “core object recognition,” the ability to rapidly recognize objects despite substantial appearance variation, is solved in the brain via a cascade of reflexive, largely feedforward computations that culminate in a powerful neuronal representation in the inferior temporal cortex. However, the algorithm that produces this solution remains little-understood. Here we review evidence ranging from individual neurons, to neuronal populations, to behavior, to computational models. We propose that understanding this algorithm will require using neuronal and psychophysical data to sift through many computational models, each based on building blocks of small, canonical sub-networks with a common functional goal. PMID:22325196

  1. Species delimitation in plants using the Qinghai–Tibet Plateau endemic Orinus (Poaceae: Tridentinae) as an example

    PubMed Central

    Su, Xu; Wu, Guili; Li, Lili; Liu, Jianquan

    2015-01-01

    Background and Aims Accurate identification of species is essential for the majority of biological studies. However, defining species objectively and consistently remains a challenge, especially for plants distributed in remote regions where there is often a lack of sufficient previous specimens. In this study, multiple approaches and lines of evidence were used to determine species boundaries for plants occurring in the Qinghai–Tibet Plateau, using the genus Orinus (Poaceae) as a model system for an integrative approach to delimiting species. Methods A total of 786 individuals from 102 populations of six previously recognized species were collected for niche, morphological and genetic analyses. Three plastid DNA regions (matK, rbcL and trnH-psbA) and one nuclear DNA region [internal transcribed space (ITS)] were sequenced. Key Results Whereas six species had been previously recognized, statistical analyses based on character variation, molecular data and niche differentiation identified only two well-delimited clusters, together with a third possibly originating from relatively recent hybridization between, or historical introgression from, the other two. Conclusions Based on a principle of integrative species delimitation to reconcile different sources of data, the results provide compelling evidence that the six previously recognized species of the genus Orinus that were examined should be reduced to two, with new circumscriptions, and a third, identified in this study, should be described as a new species. This empirical study highlights the value of applying genetic differentiation, morphometric statistics and ecological niche modelling in an integrative approach to re-circumscribing species boundaries. The results produce relatively objective, operational and unbiased taxonomic classifications of plants occurring in remote regions. PMID:25987712

  2. Species delimitation in plants using the Qinghai-Tibet Plateau endemic Orinus (Poaceae: Tridentinae) as an example.

    PubMed

    Su, Xu; Wu, Guili; Li, Lili; Liu, Jianquan

    2015-07-01

    Accurate identification of species is essential for the majority of biological studies. However, defining species objectively and consistently remains a challenge, especially for plants distributed in remote regions where there is often a lack of sufficient previous specimens. In this study, multiple approaches and lines of evidence were used to determine species boundaries for plants occurring in the Qinghai-Tibet Plateau, using the genus Orinus (Poaceae) as a model system for an integrative approach to delimiting species. A total of 786 individuals from 102 populations of six previously recognized species were collected for niche, morphological and genetic analyses. Three plastid DNA regions (matK, rbcL and trnH-psbA) and one nuclear DNA region [internal transcribed space (ITS)] were sequenced. Whereas six species had been previously recognized, statistical analyses based on character variation, molecular data and niche differentiation identified only two well-delimited clusters, together with a third possibly originating from relatively recent hybridization between, or historical introgression from, the other two. Based on a principle of integrative species delimitation to reconcile different sources of data, the results provide compelling evidence that the six previously recognized species of the genus Orinus that were examined should be reduced to two, with new circumscriptions, and a third, identified in this study, should be described as a new species. This empirical study highlights the value of applying genetic differentiation, morphometric statistics and ecological niche modelling in an integrative approach to re-circumscribing species boundaries. The results produce relatively objective, operational and unbiased taxonomic classifications of plants occurring in remote regions. © The Author 2015. Published by Oxford University Press on behalf of the Annals of Botany Company. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  3. Autoantibodies in chronic hepatitis C: A clinical perspective

    PubMed Central

    Narciso-Schiavon, Janaína Luz; Schiavon, Leonardo de Lucca

    2015-01-01

    Non-organ-specific autoantibodies and thyroid autoantibodies have been frequently found in chronic carriers of hepatitis C virus (HCV). With respect to endomysial antibodies and tissue transglutaminase, it is controversial whether the prevalence of gluten-related seromarkers is higher in patients with HCV. In such cases, in addition to acknowledging any currently existing autoimmune disease, recognizing the risk of the patient developing an autoimmune disease during interferon (IFN)-based treatment must be a principle concern. From a clinical point-of-view, the presence of autoantibodies arouses suspicion that an autoimmune disease may be present or may be precipitated by IFN-based HCV treatment. In this paper, we review the prevalence of autoantibodies in individuals with hepatitis C, the clinical significance of these autoantibodies, and the approach recommended for such situations. PMID:26052396

  4. Facial expression coding in children and adolescents with autism: Reduced adaptability but intact norm-based coding.

    PubMed

    Rhodes, Gillian; Burton, Nichola; Jeffery, Linda; Read, Ainsley; Taylor, Libby; Ewing, Louise

    2018-05-01

    Individuals with autism spectrum disorder (ASD) can have difficulty recognizing emotional expressions. Here, we asked whether the underlying perceptual coding of expression is disrupted. Typical individuals code expression relative to a perceptual (average) norm that is continuously updated by experience. This adaptability of face-coding mechanisms has been linked to performance on various face tasks. We used an adaptation aftereffect paradigm to characterize expression coding in children and adolescents with autism. We asked whether face expression coding is less adaptable in autism and whether there is any fundamental disruption of norm-based coding. If expression coding is norm-based, then the face aftereffects should increase with adaptor expression strength (distance from the average expression). We observed this pattern in both autistic and typically developing participants, suggesting that norm-based coding is fundamentally intact in autism. Critically, however, expression aftereffects were reduced in the autism group, indicating that expression-coding mechanisms are less readily tuned by experience. Reduced adaptability has also been reported for coding of face identity and gaze direction. Thus, there appears to be a pervasive lack of adaptability in face-coding mechanisms in autism, which could contribute to face processing and broader social difficulties in the disorder. © 2017 The British Psychological Society.

  5. Optimal management of complications associated with achondroplasia

    PubMed Central

    Ireland, Penny J; Pacey, Verity; Zankl, Andreas; Edwards, Priya; Johnston, Leanne M; Savarirayan, Ravi

    2014-01-01

    Achondroplasia is the most common form of skeletal dysplasia, resulting in disproportionate short stature, and affects over 250,000 people worldwide. Individuals with achondroplasia demonstrate a number of well-recognized anatomical features that impact on growth and development, with a complex array of medical issues that are best managed through a multidisciplinary team approach. The complexity of this presentation, whereby individual impairments may impact upon multiple activity and participation areas, requires consideration and discussion under a broad framework to gain a more thorough understanding of the experience of this condition for individuals with achondroplasia. This paper examines the general literature and research evidence on the medical and health aspects of individuals with achondroplasia and presents a pictorial model of achondroplasia based on The International Classification of Functioning, Disability, and Health (ICF). An expanded model of the ICF will be used to review and present the current literature pertaining to the musculoskeletal, neurological, cardiorespiratory, and ear, nose, and throat impairments and complications across the lifespan, with discussion on the impact of these impairments upon activity and participation performance. Further research is required to fully identify factors influencing participation and to help develop strategies to address these factors. PMID:25053890

  6. Caregivers in China: Knowledge of Mild Cognitive Impairment

    PubMed Central

    Dai, Baozhen; Mao, Zongfu; Mei, John; Levkoff, Sue; Wang, Huali; Pacheco, Misty; Wu, Bei

    2013-01-01

    This study aimed to examine the experience and knowledge of mild cognitive impairment (MCI) among Chinese family caregivers of individuals with MCI. The sample was recruited from memory clinics in Zhongnan Hospital in Wuhan, China. In-depth semi-structured interviews were used. Thirteen family members of individuals diagnosed with MCI participated in the study. Data analysis revealed three themes: 1) initial recognition of cognitive decline; 2) experience of the diagnosis of MCI; 3) perception of cognitive decline as a normal part of aging. While family members recognized the serious consequences of memory loss (e.g. getting lost), they would typically not take their family members to see a doctor until something specific triggered their access to the medical care system. The Chinese traditional perception of dementia as part of normal aging may serve to lessen the stigma of individuals with MCI, while the term “laonian chidai” which literally translates to “stupid, demented elderly” may exacerbate the stigma associated with individuals with MCI. It is suggested that family members’ worries may be relieved by improving their access to accurate knowledge of the disease, community-based and institutional care services, and culturally appropriately words are needed for MCI. PMID:23326541

  7. Superior orientation discrimination and increased peak gamma frequency in autism spectrum conditions.

    PubMed

    Dickinson, Abigail; Bruyns-Haylett, Michael; Smith, Richard; Jones, Myles; Milne, Elizabeth

    2016-04-01

    While perception is recognized as being atypical in individuals with autism spectrum conditions (ASC), the underlying mechanisms for such atypicality are unclear. Here we test the hypothesis that individuals with ASC will show enhanced orientation discrimination compared with neurotypical observers. This prediction is based both on anecdotal report of superior discriminatory skills in ASC and also on evidence in the auditory domain that some individuals with ASC have superior pitch discrimination. In order to establish whether atypical perception might be mediated by an imbalance in the ratio of neural excitation and inhibition (E:I ratio), we also measured peak gamma frequency, which provides an indication of neural inhibition levels. Using a rigorous thresholding method, we found that orientation discrimination thresholds for obliquely oriented stimuli were significantly lower in participants with ASC. Using EEG to measure the visually induced gamma band response, we also found that peak gamma frequency was higher in participants with ASC, relative to a well-matched control group. These novel results suggest that neural inhibition may be increased in the occipital cortex of individuals with ASC. Implications for existing theories of an imbalance in the E:I ratio of ASC are discussed. (c) 2016 APA, all rights reserved).

  8. Day hospital for early intervention for individuals with psychotic disorders.

    PubMed

    Šago, Daniela; Filipčić, Igor; Lovretić, Vanja; Mayer, Nina

    2018-06-01

    In long-term outcome studies on individuals with first-episode psychosis, improved remission and recovery rates perhaps reflect the improved treatment in dedicated early intervention program. The first episode is a critical period in which individuals with psychosis, as well as members of their families, are confronted with the illness for the first time. Until nowadays, treatment of first psychotic episodes in Croatia has usually been provided in hospital setting. The day hospital provides comprehensive therapeutic approach that refers to early systematic application of all available and effective therapeutic methods in the initial phases of psychotic disorders, and aims to attain and maintain remission and recovery, as well as insight and adherence to treatment. The day hospital is a time-limited structured program that comprises diagnostic procedures, treatment and rehabilitation based on various group psychotherapy and socio-therapy approaches. It is cheaper than hospital treatment and preferred by patients and their families. The importance of involving family members along with patients in the therapeutic process is recognized. The aim of this paper is to present the first day hospital for early intervention and treatment of individuals with psychotic disorder, established within Psychiatric hospital "Sveti Ivan", Zagreb, Croatia.

  9. The Inclusion of Multiple Exceptional Gifted Students in Talent Development Programmes: Interaction Synthesis of Both Provision Form and Content

    ERIC Educational Resources Information Center

    Gyarmathy, Éva; Senior, John

    2018-01-01

    Models of giftedness in the 21st century tend to describe talent as a social construct. Research now indicates that certain talented populations that are composed of multiple exceptional individuals are excluded from talent development programmes. Recognizing how well the environment best fits individual needs at particular key developmental…

  10. Who Experiences Growth in News Media Literacy and Why Does It Matter? Examining Education, Individual Differences, and Democratic Outcomes

    ERIC Educational Resources Information Center

    Tully, Melissa; Vraga, Emily K.

    2018-01-01

    Developing news media literacy skills is recognized as an important part of becoming an informed citizen, but not enough research examines how growth in media literacy differs by individual characteristics. Using a panel study of undergraduate students, we examine which predispositions predict growth in news media literacy beliefs over the…

  11. Recognizing the importance of autism awareness, supporting efforts to increase funding for research into the causes and treatment of autism and to improve training and support for individuals with autism and those who care for individuals with autism.

    THOMAS, 111th Congress

    Rep. Doyle, Michael F. [D-PA-14

    2009-04-02

    House - 05/14/2009 Referred to the Subcommittee on Early Childhood, Elementary, and Secondary Education. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  12. Individuation Experience Predicts Other-Race Effects in Holistic Processing for Both Caucasian and Black Participants

    ERIC Educational Resources Information Center

    Bukach, Cindy M.; Cottle, Jasmine; Ubiwa, JoAnna; Miller, Jessica

    2012-01-01

    Same-race (SR) faces are recognized better than other-race (OR) faces, and this other-race effect (ORE) is correlated with experience. SR faces are also processed more holistically than OR faces, suggesting one possible mechanism for poorer performance on OR faces. Studies of object expertise have shown that individuating experiences are necessary…

  13. An Investigation into the Secondary Schools In-Service Teachers' Selected Variables on Interactive Computer Technology (ICT) Competency

    ERIC Educational Resources Information Center

    Adodo, S. O.

    2012-01-01

    The use of computer technologies has come to stay, an individual, group of individual and society who is yet to recognize this fact is merely living. The introduction of Information and Communication Technology (ICT) into the education industry has caused transformation in instructional process. The study investigated the in-service teachers…

  14. Research on Motivation in Collaborative Learning: Moving beyond the Cognitive-Situative Divide and Combining Individual and Social Processes

    ERIC Educational Resources Information Center

    Jarvela, Sanna; Volet, Simone; Jarvenoja, Hanna

    2010-01-01

    In this article we propose that in order to advance our understanding of motivation in collaborative learning we should move beyond the cognitive-situative epistemological divide and combine individual and social processes. Our claim is that although recent research has recognized the importance of social aspects in emerging and sustained…

  15. Empathic Brain Responses in Insula Are Modulated by Levels of Alexithymia but Not Autism

    ERIC Educational Resources Information Center

    Bird, Geoffrey; Silani, Giorgia; Brindley, Rachel; White, Sarah; Frith, Uta; Singer, Tania

    2010-01-01

    Difficulties in social cognition are well recognized in individuals with autism spectrum conditions (henceforth "autism"). Here we focus on one crucial aspect of social cognition: the ability to empathize with the feelings of another. In contrast to theory of mind, a capacity that has often been observed to be impaired in individuals with autism,…

  16. Individuality That is Unheard of: Systematic Temporal Deviations in Scale Playing Leave an Inaudible Pianistic Fingerprint

    PubMed Central

    Van Vugt, Floris Tijmen; Jabusch, Hans-Christian; Altenmüller, Eckart

    2013-01-01

    Whatever we do, we do it in our own way, and we recognize master artists by small samples of their work. This study investigates individuality of temporal deviations in musical scales in pianists in the absence of deliberate expressive intention. Note-by-note timing deviations away from regularity form a remarkably consistent “pianistic fingerprint.” First, eight professional pianists played C-major scales in two sessions, separated by 15 min. Euclidian distances between deviation traces originating from different pianists were reliably larger than traces originating from the same pianist. As a result, a simple classifier that matched deviation traces by minimizing their distance was able to recognize each pianist with 100% accuracy. Furthermore, within each pianist, fingerprints produced by the same movements were more similar than fingerprints resulting in the same scale sound. This allowed us to conclude that the fingerprints are mostly neuromuscular rather than intentional or expressive in nature. However, human listeners were not able to distinguish the temporal fingerprints by ear. Next, 18 pianists played C-major scales on a normal or muted piano. Recognition rates ranged from 83 to 100%, further supporting the view that auditory feedback is not implicated in the creation of the temporal signature. Finally, 20 pianists were recognized 20 months later at above chance level, showing signature effects to be long lasting. Our results indicate that even non-expressive playing of scales reveals consistent, partially effector-unspecific, but inaudible inter-individual differences. We suggest that machine learning studies into individuality in performance will need to take into account unintentional but consistent variability below the perceptual threshold. PMID:23519688

  17. Captive Bottlenose Dolphins Do Discriminate Human-Made Sounds Both Underwater and in the Air

    PubMed Central

    Lima, Alice; Sébilleau, Mélissa; Boye, Martin; Durand, Candice; Hausberger, Martine; Lemasson, Alban

    2018-01-01

    Bottlenose dolphins (Tursiops truncatus) spontaneously emit individual acoustic signals that identify them to group members. We tested whether these cetaceans could learn artificial individual sound cues played underwater and whether they would generalize this learning to airborne sounds. Dolphins are thought to perceive only underwater sounds and their training depends largely on visual signals. We investigated the behavioral responses of seven dolphins in a group to learned human-made individual sound cues, played underwater and in the air. Dolphins recognized their own sound cue after hearing it underwater as they immediately moved toward the source, whereas when it was airborne they gazed more at the source of their own sound cue but did not approach it. We hypothesize that they perhaps detected modifications of the sound induced by air or were confused by the novelty of the situation, but nevertheless recognized they were being “targeted.” They did not respond when hearing another group member’s cue in either situation. This study provides further evidence that dolphins respond to individual-specific sounds and that these marine mammals possess some capacity for processing airborne acoustic signals. PMID:29445350

  18. Incorporating food addiction into disordered eating: the disordered eating food addiction nutrition guide (DEFANG).

    PubMed

    Wiss, David A; Brewerton, Timothy D

    2017-03-01

    Although not formally recognized by the DSM-5, food addiction (FA) has been well described in the scientific literature. FA has emerged as a clinical entity that is recognized within the spectrum of disordered eating, particularly in patients with bulimia nervosa, binge-eating disorder and/or co-occurring addictive disorders and obesity. Integrating the concept of FA into the scope of disordered eating has been challenging for ED treatment professionals, since there is no well-accepted treatment model. The confusion surrounding the implications of FA, as well as the impact of the contemporary Westernized diet, may contribute to poor treatment outcomes. The purpose of this review is twofold. The first is to briefly explore the relationships between EDs and addictions, and the second is to propose a new model of conceptualizing and treating EDs that incorporates recent data on FA. Since treatment for EDs should vary based on individual assessment and diagnosis, the Disordered Eating Food Addiction Nutrition Guide (DEFANG) is presented as a tool for framing treatment goals and helping patients achieve sustainable recovery.

  19. International military operations and mental health--A review.

    PubMed

    Kaikkonen, Noora M; Laukkala, Tanja

    2016-01-01

    Volunteering in international military missions has been scrutinized for its effects on mental health. Different kinds of exposures to traumatic events are associated with a variety of mental disorders, mainly heightened rates of post-traumatic stress disorder (PTSD) and alcohol abuse. Based on the literature we discuss risk and protective factors concerning the psychological well-being of soldiers attending to international military operations. A systematic literature search was carried out using relevant search terms to identify the articles for this review. The ability to recognize and treat acute stress reactions during deployments is important. Post-deployment psychosocial support and services have a role in lowering barriers to care, diminishing stigma and also in recognizing individuals who suffer from psychological distress or psychiatric symptoms, to connect them with appropriate care. Further investigation of gender differences and the role of stigmatization is warranted. Most of those participating in international military operations are repatriated without problems, but repeated exposure to combat situations and other stressors may affect mental health in various ways. Stigmatization is still a barrier to care.

  20. A national geographic framework for guiding conservation on a landscape scale

    USGS Publications Warehouse

    Millard, Michael J.; Czarnecki, Craig A.; Morton, John M.; Brandt, Laura A.; Briggs, Jennifer S.; Shipley, Frank S.; Sayre, Roger G.; Sponholtz, Pamela J.; Perkins, David; Simpkins, Darin G.; Taylor, Janith

    2012-01-01

    The U.S. Fish and Wildlife Service, along with the global conservation community, has recognized that the conservation challenges of the 21st century far exceed the responsibilities and footprint of any individual agency or program. The ecological effects of climate change and other anthropogenic stressors do not recognize geopolitical boundaries and, as such, demand a national geographic framework to provide structure for cross-jurisdictional and landscape-scale conservation strategies. In 2009, a new map of ecologically based conservation regions in which to organize capacity and implement strategic habitat conservation was developed using rapid prototyping and expert elicitation by an interagency team of U.S. Fish and Wildlife Service and U.S. Geological Survey scientists and conservation professionals. Incorporating Bird Conservation Regions, Freshwater Ecoregions, and U.S. Geological Survey hydrologic unit codes, the new geographic framework provides a spatial template for building conservation capacity and focusing biological planning and conservation design efforts. The Department of Interior's Landscape Conservation Cooperatives are being organized in these new conservation regions as multi-stakeholder collaborations for improved conservation science and management.

  1. 46 CFR Appendix B to Part 404 - Ratemaking Definitions and Formulas

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... (the Interest Expense). (10) Investment Base (separately determined)—means the net recognized capital... pilotage operations, that capital is excluded from the rate base. (11) Return on Investment—means the...) Regulatory Investment (Investment Base) is the recognized capital investment in the useful assets employed by...

  2. The embodiment of emotion: language use during the feeling of social emotions predicts cortical somatosensory activity.

    PubMed

    Saxbe, Darby E; Yang, Xiao-Fei; Borofsky, Larissa A; Immordino-Yang, Mary Helen

    2013-10-01

    Complex social emotions involve both abstract cognitions and bodily sensations, and individuals may differ on their relative reliance on these. We hypothesized that individuals' descriptions of their feelings during a semi-structured emotion induction interview would reveal two distinct psychological styles-a more abstract, cognitive style and a more body-based, affective style-and that these would be associated with somatosensory neural activity. We examined 28 participants' open-ended verbal responses to admiration- and compassion-provoking narratives in an interview and BOLD activity to the same narratives during subsequent functional magnetic resonance imaging scanning. Consistent with hypotheses, individuals' affective and cognitive word use were stable across emotion conditions, negatively correlated and unrelated to reported emotion strength in the scanner. Greater use of affective relative to cognitive words predicted more activation in SI, SII, middle anterior cingulate cortex and insula during emotion trials. The results suggest that individuals' verbal descriptions of their feelings reflect differential recruitment of neural regions supporting physical body awareness. Although somatosensation has long been recognized as an important component of emotion processing, these results offer 'proof of concept' that individual differences in open-ended speech reflect different processing styles at the neurobiological level. This study also demonstrates SI involvement during social emotional experience.

  3. Chemosensory age discrimination in the snake Boa constrictor (Serpentes: Boidae).

    PubMed

    Gabirot, Marianne; Picerno, Pablo; Valencia, Jorge; Lopez, Pilar; Martin, José

    2012-12-01

    Many snakes are able to use their chemosensory system to detect scent of conspecifics, which is important in many social contexts. Age discrimination based on chemical cues may be especially important to ensure access to sexually mature potential partners. In this study, we used 24 individual Boa constrictor snakes (12 adults mature and 12 non-mature individuals) that had been captured in different areas of Ecuador, and were maintained in captivity at the Vivarium of Quito. We used tongue-flick experiments to examine whether these snakes were able to discriminate between scents from mature and non-mature individuals. Results showed that B. constrictor snakes used chemical cues to recognize conspecifics and that the scent of individuals of different ages elicited chemosensory responses of different magnitudes. The scents from adult conspecifics elicited the quickest and highest chemosensory responses (i.e., short latency times and high tongue-flick rates), although we did not find differential responses to scent of males and females. The magnitude of the responses was lower to scent of sub adult individuals, and then even lower to scent of juvenile snakes, but in all cases the scent of snakes was discriminated from a blank control. We discuss the potential chemical mechanisms that may allow age recognition and its implications for social and sexual behavior of this snake species.

  4. Prospective memory impairment and its implications for community living skills in bipolar disorder.

    PubMed

    Au, Raymond W C; Ungvari, Gabor S; Lee, Edwin; Man, David; Shum, David H K; Xiang, Yu-Tao; Tang, Wai-Kwong

    2013-12-01

    Prospective memory (PM) refers to the ability to undertake intended actions in the future. The functional significance of PM in bipolar disorder (BD) has not yet been investigated. This study examined PM impairment and its role in community living skills in clinically stable individuals with BD. Seventy-six individuals with BD and 44 healthy individuals were assessed with the Chinese version of the Cambridge Prospective Memory Test. Socio-demographic characteristics, retrospective memory (RM; the ability to recall or recognize past information), and intelligence were also measured in all participants. The clinical condition and community living skills of patients with BD were rated independently with standardized instruments. Patients with BD showed PM impairment and their PM total scores independently predicted the level of community living skills in regression analyses. In follow-up analyses, the contribution was found to be accounted for by the time-based PM scores. Given the expanding body of research on the utility of PM in predicting functioning, these findings further support the role of PM in community living skills in individuals with BD. The results suggest that PM training might be an integral part of clinical rehabilitation devised for individuals with BD. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  5. The relationship of depression with the level of blood pressure in population-based Kangbuk Samsung Health Study.

    PubMed

    Park, Sung Keun; Jung, Ju Young; Ryoo, Jae-Hong; Oh, Chang-Mo; Lee, Jae-Hon; Pan, Zihang; Mansur, Rodrigo B; Shekotikhina, Margarita; McIntyre, Roger S; Choi, Joong-Myung

    2018-05-01

    There has been increasing evidence about psychosomatic relationship between mood disorder and blood pressure (BP). However, the degree to which BP categories are associated with depression has been less well described. Thus, this study was to investigate the association of depression with BP categories. A total of 90,643 men and 68,933 women were enrolled in this study. They were stratified into four groups (normal, prehypertension, newly diagnosed hypertension, and recognized hypertension) according to the BP levels and the history of hypertension. Center for Epidemiological Studies-Depression was used to evaluate the depressive symptom, and the degree of depression was evaluated by the cutoff of Center for Epidemiological Studies-Depression (mild: 16-20, moderate: 21-24, severe: ≥25). The multivariate logistic regression was used in calculating odds ratios for depression according to the four BP categories, with adjustment for multiple confounding factors. Subgroup analysis was conducted by gender and age. The adjusted odds ratios for depression tended to decrease from normal to newly diagnosed hypertension, but significantly increased in recognized hypertension (normal: reference, prehypertension: 0.85 [0.80-0.91], newly diagnosed hypertension: 0.75 [0.65-0.86], recognized hypertension: 1.11 [1.03-1.20]). Subgroup analysis also indicated the similar pattern of relationship, which was more prominent in male and middle-aged subgroup than any other subgroups. Depression was inversely associated with elevated BP. However, recognized hypertension had the increased likelihood of depression in male and young age group. These findings suggest that the association between depression and BP may be moderated by the chronicity of hypertension in men and young individuals. Copyright © 2018 American Society of Hypertension. Published by Elsevier Inc. All rights reserved.

  6. Motion Recognition and Modifying Motion Generation for Imitation Robot Based on Motion Knowledge Formation

    NASA Astrophysics Data System (ADS)

    Okuzawa, Yuki; Kato, Shohei; Kanoh, Masayoshi; Itoh, Hidenori

    A knowledge-based approach to imitation learning of motion generation for humanoid robots and an imitative motion generation system based on motion knowledge learning and modification are described. The system has three parts: recognizing, learning, and modifying parts. The first part recognizes an instructed motion distinguishing it from the motion knowledge database by the continuous hidden markov model. When the motion is recognized as being unfamiliar, the second part learns it using locally weighted regression and acquires a knowledge of the motion. When a robot recognizes the instructed motion as familiar or judges that its acquired knowledge is applicable to the motion generation, the third part imitates the instructed motion by modifying a learned motion. This paper reports some performance results: the motion imitation of several radio gymnastics motions.

  7. Sexual dimorphism in teeth? Clinical relevance.

    PubMed

    Radlanski, Ralf J; Renz, Herbert; Hopfenmüller, Werner

    2012-04-01

    Many morphometric studies show a sexual dimorphism in human teeth. We wanted to know whether it is possible to determine the sex of an individual if only the anterior teeth are visible. Fifty intraoral photographs showing the front tooth region of female and male individuals (age: from 7 to 75 years) were randomly arranged in actual size on a questionnaire. The lip region was covered in each case. Besides "female" and "male", one was also able to check "?" if undecided. The questionnaires were distributed to 50 expert test persons (dentists, dental technicians, dental assistants, and students of dental medicine) and to 50 laymen and were all returned for evaluation. Although the correct sex was recognized on single photographs to a maximum of 76%, it was incorrect in 69% on other photographs. Altogether, the statistical evaluation showed that in most cases, the sex was only recognized correctly by one half, and incorrect by the other half. It can be concluded that a sexual dimorphism of human teeth-although measurable morphometrically-could not be recognized visually on the basis of photographs of the front tooth region. Neither experts in the field of dentistry nor laymen were able to properly distinguish between male and female teeth.

  8. Multi-locus Analyses Reveal Four Giraffe Species Instead of One.

    PubMed

    Fennessy, Julian; Bidon, Tobias; Reuss, Friederike; Kumar, Vikas; Elkan, Paul; Nilsson, Maria A; Vamberger, Melita; Fritz, Uwe; Janke, Axel

    2016-09-26

    Traditionally, one giraffe species and up to eleven subspecies have been recognized [1]; however, nine subspecies are commonly accepted [2]. Even after a century of research, the distinctness of each giraffe subspecies remains unclear, and the genetic variation across their distribution range has been incompletely explored. Recent genetic studies on mtDNA have shown reciprocal monophyly of the matrilines among seven of the nine assumed subspecies [3, 4]. Moreover, until now, genetic analyses have not been applied to biparentally inherited sequence data and did not include data from all nine giraffe subspecies. We sampled natural giraffe populations from across their range in Africa, and for the first time individuals from the nominate subspecies, the Nubian giraffe, Giraffa camelopardalis camelopardalis Linnaeus 1758 [5], were included in a genetic analysis. Coalescence-based multi-locus and population genetic analyses identify at least four separate and monophyletic clades, which should be recognized as four distinct giraffe species under the genetic isolation criterion. Analyses of 190 individuals from maternal and biparental markers support these findings and further suggest subsuming Rothschild's giraffe into the Nubian giraffe, as well as Thornicroft's giraffe into the Masai giraffe [6]. A giraffe survey genome produced valuable data from microsatellites, mobile genetic elements, and accurate divergence time estimates. Our findings provide the most inclusive analysis of giraffe relationships to date and show that their genetic complexity has been underestimated, highlighting the need for greater conservation efforts for the world's tallest mammal. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. [Barriers to evidence-based medicine encountered among GPs - an issue based on misunderstanding? A qualitative study in the general practice setting].

    PubMed

    Bölter, Regine; Kühlein, Thomas; Ose, Dominik; Götz, Katja; Freund, Tobias; Szecsenyi, Joachim; Miksch, Antje

    2010-01-01

    The Chronic Care Model (CCM) is a framework for the structured care of patients with chronic conditions. It requires access of both physicians and patients to scientific evidence in order to facilitate shared treatment decision-making on the basis of the patient's individual needs and the best available external evidence. The aim of this study was to find out whether general practitioners (GP) actually make use of evidence-based information and guidelines and whether and how they communicate this information to their patients. We interviewed 14 general practitioners and conducted a content analysis. The majority of these GPs take a sceptical view towards evidence-based guidelines. Their main point of criticism is that guidelines disregard the individual patient's reality and life style. Instead, GPs emphasize the relevance of their own knowledge of the personal and medical history of and the continual care for their patients. Since GPs themselves often do not accept guidelines, they seldom impart their content to their patients. According to the GPs' experience there are contradictions between guideline-conformant therapy and individual treatment. The integrative character of evidence-based medicine is not recognized. The reason is that evidence-based medicine is equated with guidelines and trial results by the majority of the GPs interviewed. To facilitate guideline implementation in everyday practice GPs need to be provided with adequate access to scientific evidence and an understanding of the intentions of guidelines. If the doctors themselves do not accept guidelines, they will not share them with their patients. It must be made clear that guidelines are not intended as normative demands for a specific therapy for every patient, but are rather meant to assist the physician with his struggle for the best therapy for individual patients. Copyright © 2010. Published by Elsevier GmbH.

  10. 20 CFR 10.700 - May a claimant designate a representative?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... withdraws the authorization of the first individual. In addition, OWCP will recognize only certain types of... includes presenting or eliciting evidence, making arguments on facts or the law, and obtaining information...

  11. Perspectives on dyslexia

    PubMed Central

    Siegel, Linda S

    2006-01-01

    Dyslexia, or a reading disability, occurs when an individual has significant difficulty with speed and accuracy of word decoding. Comprehension of text and spelling are also affected. The diagnosis of dyslexia involves the use of reading tests, but the continuum of reading performance means that any cutoff point is arbitrary. The IQ score does not play a role in the diagnosis of dyslexia. The cognitive difficulties of dyslexics include problems with speech perception, recognizing and manipulating the basic sounds in a language, language memory, and learning the sounds of letters. Dyslexia is a neurological condition with a genetic basis. There are abnormalities in the brains of dyslexic individuals. There are also differences in the electrophysiological and structural characteristics of the brains of dyslexics. Physicians play a particularly important role in recognizing children who are at risk for dyslexia and helping their parents obtain the proper assessment. PMID:19030329

  12. Essential Psychoanalysis: Toward a Re-Appraisal of the Relationship between Psychoanalysis and Dynamic Psychotherapy.

    PubMed

    Sripada, Bhaskar

    2015-09-01

    Freud stated that any line of investigation which recognizes transference and resistance, regardless of its results, was entitled to call itself psychoanalysis (Freud, 1914a, p. 16). Separately he wrote that psychoanalysis was the science of unconscious mental processes (Freud, 1925, p. 70). Combining these two ideas defines Essential Psychoanalysis: Any line of treatment, theory, or science which recognizes the facts of unconscious, transference, or resistance, and takes them as the starting point of its work, regardless of its results, is psychoanalysis. Freud formulated two conflicting definitions of psychoanalysis: Essential Psychoanalysis, applicable to all analysts regardless of their individuality and Extensive Psychoanalysis, modeled on his individuality. They differ in how psychoanalytic technique is viewed. For Essential Psychoanalysis, flexible recommendations constitute psychoanalytic technique, whereas for Extensive Psychoanalysis, rules constitute a key part of psychoanalytic technique.

  13. Recognizing Age-Separated Face Images: Humans and Machines

    PubMed Central

    Yadav, Daksha; Singh, Richa; Vatsa, Mayank; Noore, Afzel

    2014-01-01

    Humans utilize facial appearance, gender, expression, aging pattern, and other ancillary information to recognize individuals. It is interesting to observe how humans perceive facial age. Analyzing these properties can help in understanding the phenomenon of facial aging and incorporating the findings can help in designing effective algorithms. Such a study has two components - facial age estimation and age-separated face recognition. Age estimation involves predicting the age of an individual given his/her facial image. On the other hand, age-separated face recognition consists of recognizing an individual given his/her age-separated images. In this research, we investigate which facial cues are utilized by humans for estimating the age of people belonging to various age groups along with analyzing the effect of one's gender, age, and ethnicity on age estimation skills. We also analyze how various facial regions such as binocular and mouth regions influence age estimation and recognition capabilities. Finally, we propose an age-invariant face recognition algorithm that incorporates the knowledge learned from these observations. Key observations of our research are: (1) the age group of newborns and toddlers is easiest to estimate, (2) gender and ethnicity do not affect the judgment of age group estimation, (3) face as a global feature, is essential to achieve good performance in age-separated face recognition, and (4) the proposed algorithm yields improved recognition performance compared to existing algorithms and also outperforms a commercial system in the young image as probe scenario. PMID:25474200

  14. Recognizing age-separated face images: humans and machines.

    PubMed

    Yadav, Daksha; Singh, Richa; Vatsa, Mayank; Noore, Afzel

    2014-01-01

    Humans utilize facial appearance, gender, expression, aging pattern, and other ancillary information to recognize individuals. It is interesting to observe how humans perceive facial age. Analyzing these properties can help in understanding the phenomenon of facial aging and incorporating the findings can help in designing effective algorithms. Such a study has two components--facial age estimation and age-separated face recognition. Age estimation involves predicting the age of an individual given his/her facial image. On the other hand, age-separated face recognition consists of recognizing an individual given his/her age-separated images. In this research, we investigate which facial cues are utilized by humans for estimating the age of people belonging to various age groups along with analyzing the effect of one's gender, age, and ethnicity on age estimation skills. We also analyze how various facial regions such as binocular and mouth regions influence age estimation and recognition capabilities. Finally, we propose an age-invariant face recognition algorithm that incorporates the knowledge learned from these observations. Key observations of our research are: (1) the age group of newborns and toddlers is easiest to estimate, (2) gender and ethnicity do not affect the judgment of age group estimation, (3) face as a global feature, is essential to achieve good performance in age-separated face recognition, and (4) the proposed algorithm yields improved recognition performance compared to existing algorithms and also outperforms a commercial system in the young image as probe scenario.

  15. Essential use cases for pedagogical patterns

    NASA Astrophysics Data System (ADS)

    Derntl, Michael; Botturi, Luca

    2006-06-01

    Coming from architecture, through computer science, pattern-based design spread into other disciplines and is nowadays recognized as a powerful way of capturing and reusing effective design practice. However, current pedagogical pattern approaches lack widespread adoption, both by users and authors, and are still limited to individual initiatives. This paper contributes to creating a shared understanding of what a pattern system is by defining the key terms. Moreover, the paper builds upon and extends a set of existing functional and non-functional requirements for pattern systems, adds structure to these requirements, and derives essential use cases following a goal-based approach for both pattern maintenance and pattern application. Finally, implications concerning the pedagogical use of pattern-based design are drawn, concluding that a stronger focus on the underlying (pedagogical) value system is required in order to make a pattern system a meaningful tool for effective educational design.

  16. Modeling Patterns of Activities using Activity Curves.

    PubMed

    Dawadi, Prafulla N; Cook, Diane J; Schmitter-Edgecombe, Maureen

    2016-06-01

    Pervasive computing offers an unprecedented opportunity to unobtrusively monitor behavior and use the large amount of collected data to perform analysis of activity-based behavioral patterns. In this paper, we introduce the notion of an activity curve , which represents an abstraction of an individual's normal daily routine based on automatically-recognized activities. We propose methods to detect changes in behavioral routines by comparing activity curves and use these changes to analyze the possibility of changes in cognitive or physical health. We demonstrate our model and evaluate our change detection approach using a longitudinal smart home sensor dataset collected from 18 smart homes with older adult residents. Finally, we demonstrate how big data-based pervasive analytics such as activity curve-based change detection can be used to perform functional health assessment. Our evaluation indicates that correlations do exist between behavior and health changes and that these changes can be automatically detected using smart homes, machine learning, and big data-based pervasive analytics.

  17. Evidence for kind representations in the absence of language: experiments with rhesus monkeys (Macaca mulatta).

    PubMed

    Phillips, Webb; Santos, Laurie R

    2007-03-01

    How do we come to recognize and represent different kinds of objects in the world? Some developmental psychologists have hypothesized that learning language plays a crucial role in this capacity. If this hypothesis were correct, then non-linguistic animals should lack the capacity to represent objects as kinds. Previous research with rhesus monkeys (Macaca mulatta) has shown that this species can successfully individuate different kinds of objects - monkeys who saw one kind of object hidden inside a box searched longer after finding a different kind of object. However, in these studies and the infant studies on which they were based, the objects to be individuated differed both in kind and in properties. Thus, subjects in these experiments may not be representing the kinds of objects per se, but instead only their immediate perceptual properties. Here, we show that rhesus monkeys successfully individuate different kinds of objects even when their perceptual properties are held constant. Although these data provide the best evidence to date that language is not necessary to represent kinds, we discuss our findings in terms of possible associative hypotheses as well.

  18. Origins of species: acquired genomes and individuality

    NASA Technical Reports Server (NTRS)

    Margulis, L.

    1993-01-01

    Entire genomes with their accompanying protein synthetic systems are transferred throughout the biosphere primarily as bacteria and protists which become symbionts as they irreversibly integrate into pre-existing organisms to form more complex individuals. Individualization is stabilized by simultaneous transmission of once-separate heterologous genetic systems. The origin of new species is hypothesized to correlate with the acquisition, integration and subsequent inheritance of such acquired microbial genomes. These processes were recognized by Mereschkovsky ("Symbiogenesis" in Russian, 1909) and by Wallin ("Symbionticism", see p. 181, this issue).

  19. Analysis of Individuals from a Dengue-Endemic Region Helps Define the Footprint and Repertoire of Antibodies Targeting Dengue Virus 3 Type-Specific Epitopes.

    PubMed

    Andrade, Daniela V; Katzelnick, Leah C; Widman, Doug G; Balmaseda, Angel; de Silva, Aravinda M; Baric, Ralph S; Harris, Eva

    2017-09-19

    The four dengue virus serotypes (DENV1 to 4) cause dengue, a major public health problem worldwide. Individuals exposed to primary DENV infections develop serotype-specific neutralizing antibodies, including strongly neutralizing antibodies targeting quaternary epitopes. To date, no studies have measured the levels and kinetics of serum antibodies directed to such epitopes among populations in regions where dengue is endemic. Here, we use a recombinant DENV4 (rDENV4/3-M14) displaying a major DENV3 type-specific quaternary epitope recognized by human monoclonal antibody 5J7 to measure the proportion, magnitude, and kinetics of DENV3 type-specific neutralizing antibody responses targeting this epitope. Primary DENV3 sera from 30 individuals in a dengue hospital-based study in Nicaragua were studied 3, 6, 12, and 18 months post-infection, alongside samples collected annually 1 to 4 years post-primary DENV3 infection from 10 individuals in a cohort study in Nicaragua. We found substantial individual variation in the proportion of DENV3 type-specific neutralizing antibody titers attributed to the 5J7 epitope (range, 0 to 100%), with the mean significantly increasing from 22.6% to 41.4% from 3 to 18 months. We extended the transplanted DENV3 5J7 epitope on the virion (rDENV4/3-M16), resulting in increased recognition in several individuals, helping define the footprint of the epitope. However, 37% and 13% of the subjects still showed little to no recognition of the 5J7 epitope at 3 and 18 months, respectively, indicating that one or more additional DENV3 type-specific epitopes exist. Overall, this study demonstrates how DENV-immune plasma from populations from areas of endemicity, when coupled with structurally guided recombinant viruses, can help characterize the epitope-specific neutralizing antibody response in natural DENV infections, with direct implications for design and evaluation of dengue vaccines. IMPORTANCE The four serotypes of dengue virus cause dengue, a major public health burden worldwide, yet it has been challenging to develop a vaccine that is safe and equally effective against all four serotypes. More in-depth characterization of natural human neutralizing antibody responses is needed to identify determinants of protective antibody responses to all DENV serotypes. Here, we use hospital and cohort studies in a region where dengue is endemic to assess the proportion and kinetics of the DENV3 neutralizing antibody response directed to a quaternary epitope on DENV3 recognized by strongly neutralizing human monoclonal antibody 5J7, which was transplanted into a DENV4 backbone. We show that many individuals recognized the 5J7 epitope, but to various degrees over time, suggesting that additional DENV3-specific epitopes likely exist. Thus, characterization of epitope-specific neutralizing antibody responses in natural DENV infections can help define the footprint and repertoire of antibodies directed to DENV3 type-specific epitopes, with implications for dengue vaccine development. Copyright © 2017 Andrade et al.

  20. Image-based corrosion recognition for ship steel structures

    NASA Astrophysics Data System (ADS)

    Ma, Yucong; Yang, Yang; Yao, Yuan; Li, Shengyuan; Zhao, Xuefeng

    2018-03-01

    Ship structures are subjected to corrosion inevitably in service. Existed image-based methods are influenced by the noises in images because they recognize corrosion by extracting features. In this paper, a novel method of image-based corrosion recognition for ship steel structures is proposed. The method utilizes convolutional neural networks (CNN) and will not be affected by noises in images. A CNN used to recognize corrosion was designed through fine-turning an existing CNN architecture and trained by datasets built using lots of images. Combining the trained CNN classifier with a sliding window technique, the corrosion zone in an image can be recognized.

  1. CE: Original Research: Exploring Clinicians' Perceptions About Sustaining an Evidence-Based Fall Prevention Program.

    PubMed

    Porter, Rebecca B; Cullen, Laura; Farrington, Michele; Matthews, Grace; Tucker, Sharon

    2018-05-01

    : Purpose: This study aimed to address the knowledge gap between implementing and sustaining evidence-based fall prevention practices for hospitalized patients by exploring perspectives of the interprofessional health care team. A qualitative design was used to capture insights from clinicians across disciplines in a large midwestern academic medical center. Four homogenous semistructured focus groups and three individual interviews involving a total of 20 clinicians were conducted between October 2013 and March 2014. Audio-recorded data were transcribed and analyzed using inductive qualitative analysis. Two primary themes emerged from participants regarding the sustainability of an evidence-based fall prevention program: communication patterns within the interprofessional health care team and influences of hospital organizational practices and elements. Several subthemes also emerged. Participants gave nursing staff primary responsibility for fall risk assessment and prevention. Individual professional perceptions and practices, as well as organizational characteristics, affect the sustainability of evidence-based fall prevention practices. While all team members recognized patient falls as a significant quality and safety issue, most believed that direct care nurses hold primary responsibility for leading fall prevention efforts. The data support the importance of effective interprofessional team communication and organizational practices in sustaining an evidence-based fall prevention program across inpatient units. Furthermore, the data call into question the wisdom in labeling quality indicators as "nursing sensitive"; the evidence indicates that a team approach is best.

  2. Individual heterogeneity and identifiability in capture-recapture models

    USGS Publications Warehouse

    Link, W.A.

    2004-01-01

    Individual heterogeneity in detection probabilities is a far more serious problem for capture-recapture modeling than has previously been recognized. In this note, I illustrate that population size is not an identifiable parameter under the general closed population mark-recapture model Mh. The problem of identifiability is obvious if the population includes individuals with pi = 0, but persists even when it is assumed that individual detection probabilities are bounded away from zero. Identifiability may be attained within parametric families of distributions for pi, but not among parametric families of distributions. Consequently, in the presence of individual heterogeneity in detection probability, capture-recapture analysis is strongly model dependent.

  3. Elevated and cross‐responsive CD1a‐reactive T cells in bee and wasp venom allergic individuals

    PubMed Central

    Subramaniam, Sumithra; Aslam, Aamir; Misbah, Siraj A.; Salio, Mariolina; Cerundolo, Vincenzo; Moody, D Branch

    2015-01-01

    The role of CD1a‐reactive T cells in human allergic disease is unknown. We have previously shown that circulating CD1a‐reactive T cells recognize neolipid antigens generated by bee and wasp venom phospholipase, and here tested the hypothesis that venom‐responsive CD1a‐reactive T cells associate with venom allergy. Circulating T cells from bee and wasp venom allergic individuals, before and during immunotherapy, were exposed to CD1a‐transfected K562 cells in the presence of wasp or bee venom. T‐cell response was evaluated based on IFNγ, GM‐CSF, and IL‐13 cytokine production. Venom allergic individuals showed significantly higher frequencies of IFN‐γ, GM‐CSF, and IL‐13 producing CD1a‐reactive T cells responsive to venom and venom‐derived phospholipase than healthy individuals. Venom‐responsive CD1a‐reactive T cells were cross‐responsive between wasp and bee suggesting shared pathways of allergenicity. Frequencies of CD1a‐reactive T cells were initially induced during subcutaneous immunotherapy, peaking by weeks 5, but then reduced despite escalation of antigen dose. Our current understanding of venom allergy and immunotherapy is largely based on peptide and protein‐specific T cell and antibody responses. Here, we show that lipid antigens and CD1a‐reactive T cells associate with the allergic response. These data have implications for mechanisms of allergy and approaches to immunotherapy. PMID:26518614

  4. Reconsidering Anonymization-Related Concepts and the Term “Identification” Against the Backdrop of the European Legal Framework

    PubMed Central

    Schlünder, Irene

    2016-01-01

    Sharing data in biomedical contexts has become increasingly relevant, but privacy concerns set constraints for free sharing of individual-level data. Data protection law protects only data relating to an identifiable individual, whereas “anonymous” data are free to be used by everybody. Usage of many terms related to anonymization is often not consistent among different domains such as statistics and law. The crucial term “identification” seems especially hard to define, since its definition presupposes the existence of identifying characteristics, leading to some circularity. In this article, we present a discussion of important terms based on a legal perspective that it is outlined before we present issues related to the usage of terms such as unique “identifiers,” “quasi-identifiers,” and “sensitive attributes.” Based on these terms, we have tried to circumvent a circular definition for the term “identification” by making two decisions: first, deciding which (natural) identifier should stand for the individual; second, deciding how to recognize the individual. In addition, we provide an overview of anonymization techniques/methods for preventing re-identification. The discussion of basic notions related to anonymization shows that there is some work to be done in order to achieve a mutual understanding between legal and technical experts concerning some of these notions. Using a dialectical definition process in order to merge technical and legal perspectives on terms seems important for enhancing mutual understanding. PMID:27104620

  5. Getting a good night sleep? The importance of recognizing and treating nocturnal hypokinesia in Parkinson's disease.

    PubMed

    Bhidayasiri, Roongroj; Trenkwalder, Claudia

    2018-05-01

    When Parkinson's disease (PD) patients are asked about the quality of their sleep, their answers are dominated by difficulties associated with impaired mobility in bed, medically referred to as nocturnal hypokinesia. Nocturnal hypokinesia is symptomatic from the mid-stage of the disease, affecting up to 70% of PD patients, and contributes to poor sleep quality, and increased carer burden. Here we explore four areas of nocturnal hypokinesia that are relevant to clinical practice, namely: manifestations and definition; clinical assessment and objective monitoring; etiologies and contributing factors; and evidence-based therapeutic approaches. In addition, we provide an operational definition of what constitutes nocturnal hypokinesia and outline different methods of assessment, ranging from clinical interviews and rating scales to objective night-time monitoring with inertial sensors. Optimal management of nocturnal hypokinesia in PD begins with recognizing its manifestation by inquiring about cardinal symptoms and contributing factors from, not only patients, but also carers, followed by formal assessment, and the application of individualized evidence-based treatment. Night-time dopaminergic treatment is the primary therapy; however, careful clinical judgment is required to balance the benefits with the potential adverse events related to nocturnal dopaminergic stimulation. Future studies are needed to explore the practicality of home-based objective assessment of nocturnal hypokinesia, new therapeutic options not limited to dopaminergic medications, and non-pharmacologic approaches, including training on compensatory strategies and bedroom adaptations. Copyright © 2018 Elsevier Ltd. All rights reserved.

  6. Nutrition issues in Codex: health claims, nutrient reference values and WTO agreements: a conference report.

    PubMed

    Aggett, Peter J; Hathcock, John; Jukes, David; Richardson, David P; Calder, Philip C; Bischoff-Ferrari, Heike; Nicklas, Theresa; Mühlebach, Stefan; Kwon, Oran; Lewis, Janine; Lugard, Maurits J F; Prock, Peter

    2012-03-01

    Codex documents may be used as educational and consensus materials for member governments. Also, the WTO SPS Agreement recognizes Codex as the presumptive international authority on food issues. Nutrient bioavailability is a critical factor in determining the ability of nutrients to provide beneficial effects. Bioavailability also influences the quantitative dietary requirements that are the basis of nutrient intake recommendations and NRVs. Codex, EFSA and some national regulatory authorities have established guidelines or regulations that will permit several types of health claims. The scientific basis for claims has been established by the US FDA and EFSA, but not yet by Codex. Evidence-based nutrition differs from evidence-based medicine, but the differences are only recently gaining recognition. Health claims on foods may provide useful information to consumers, but many will interpret the information to mean that they can rely upon the food or nutrient to eliminate a disease risk. NRVs are designed to provide a quantitative basis for comparing the nutritive values of foods, helping to illustrate how specific foods fit into the overall diet. The INL-98 and the mean of adult male and female values provide NRVs that are sufficient when used as targets for individual intakes by most adults. WTO recognizes Codex as the primary international authority on food issues. Current regulatory schemes based on recommended dietary allowances are trade restrictive. A substantial number of decisions by the EFSA could lead to violation of WTO agreements.

  7. "Physics and the Girly Girl--There Is a Contradiction Somewhere": Doctoral Students' Positioning around Discourses of Gender and Competence in Physics

    ERIC Educational Resources Information Center

    Gonsalves, Allison J.

    2014-01-01

    Doctoral physics students have stories about what kinds of actions, behaviours and ways of doing physics allow individuals to be recognized as physicists. Viewing a physics department as a case study, and individual participants as embedded cases, this study used a sociocultural approach to examine the ways doctoral students construct these…

  8. Mentor awards

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    The Association of Women in Science (AWIS) and the American Indian Science and Engineering Society (AISES) were two of 19 institutions and individuals that received presidential awards for excellence in science, mathematics, and engineering mentoring, on September 11.Neal Lane, Director of the National Science Foundation, says the awards, which include $10,000 grants, recognize “individuals and institutions working to heighten the participation of underrepresented groups in science, mathematics, and engineering.”

  9. The Level of Career Success for Talented Students and Its Relation with Gender, Center and Educational Level

    ERIC Educational Resources Information Center

    Al Hajjat, Adel Tawfeeq

    2017-01-01

    The aim of this study is to recognize the level of career success for talented students who are graduates from programs of talented individuals in Jubilee School in Amman city and pioneering center for talented individuals in Salt city. The sample of the study includes (162) graduates from the mentioned programs. Also the study aimed to know the…

  10. The relationship of organizational needs to leadership styles.

    PubMed

    Wroblewski, D

    1981-12-01

    Technologists bring to the radiology department individual needs which are incorporated into their work environment. These needs can be termed "satisfiers"; they can also be categorized. The ability to recognize individual or group needs gives a manager the opportunity to alter leadership style in conjunction with the situation. The ability to satisfy needs can be a beneficial tool towards group motivation for goal attainment.

  11. Pragmatic Language Assessment in Williams Syndrome: A Comparison of the Test of Pragmatic Language--2 and the Children's Communication Checklist--2

    ERIC Educational Resources Information Center

    Hoffmann, Anne; Martens, Marilee A.; Fox, Robert; Rabidoux, Paula; Andridge, Rebecca

    2013-01-01

    Purpose: Individuals with Williams syndrome (WS) are recognized as having a strong desire for social relationships, yet many of them have difficulty forming and maintaining peer relationships. One cause may be impairments in pragmatic language. The current study compared the assessment of pragmatic language skills in individuals with WS using the…

  12. 2015 Gulf Guardian Award Winners

    EPA Pesticide Factsheets

    The Gulf of Mexico Program Partnership developed the Gulf Guardian awards as a way to recognize and honor the businesses, community groups, individuals, and agencies that are taking positive steps to keep the Gulf healthy, beautiful and productive.

  13. 2017 Gulf Guardian Award Winners

    EPA Pesticide Factsheets

    The Gulf of Mexico Program Partnership developed the Gulf Guardian awards as a way to recognize and honor the businesses, community groups, individuals, and agencies that are taking positive steps to keep the Gulf healthy, beautiful and productive.

  14. Local Orientation and the Evolution of Foraging: Changes in Decision Making Can Eliminate Evolutionary Trade-offs

    PubMed Central

    van der Post, Daniel J.; Semmann, Dirk

    2011-01-01

    Information processing is a major aspect of the evolution of animal behavior. In foraging, responsiveness to local feeding opportunities can generate patterns of behavior which reflect or “recognize patterns” in the environment beyond the perception of individuals. Theory on the evolution of behavior generally neglects such opportunity-based adaptation. Using a spatial individual-based model we study the role of opportunity-based adaptation in the evolution of foraging, and how it depends on local decision making. We compare two model variants which differ in the individual decision making that can evolve (restricted and extended model), and study the evolution of simple foraging behavior in environments where food is distributed either uniformly or in patches. We find that opportunity-based adaptation and the pattern recognition it generates, plays an important role in foraging success, particularly in patchy environments where one of the main challenges is “staying in patches”. In the restricted model this is achieved by genetic adaptation of move and search behavior, in light of a trade-off on within- and between-patch behavior. In the extended model this trade-off does not arise because decision making capabilities allow for differentiated behavioral patterns. As a consequence, it becomes possible for properties of movement to be specialized for detection of patches with more food, a larger scale information processing not present in the restricted model. Our results show that changes in decision making abilities can alter what kinds of pattern recognition are possible, eliminate an evolutionary trade-off and change the adaptive landscape. PMID:21998571

  15. Local orientation and the evolution of foraging: changes in decision making can eliminate evolutionary trade-offs.

    PubMed

    van der Post, Daniel J; Semmann, Dirk

    2011-10-01

    Information processing is a major aspect of the evolution of animal behavior. In foraging, responsiveness to local feeding opportunities can generate patterns of behavior which reflect or "recognize patterns" in the environment beyond the perception of individuals. Theory on the evolution of behavior generally neglects such opportunity-based adaptation. Using a spatial individual-based model we study the role of opportunity-based adaptation in the evolution of foraging, and how it depends on local decision making. We compare two model variants which differ in the individual decision making that can evolve (restricted and extended model), and study the evolution of simple foraging behavior in environments where food is distributed either uniformly or in patches. We find that opportunity-based adaptation and the pattern recognition it generates, plays an important role in foraging success, particularly in patchy environments where one of the main challenges is "staying in patches". In the restricted model this is achieved by genetic adaptation of move and search behavior, in light of a trade-off on within- and between-patch behavior. In the extended model this trade-off does not arise because decision making capabilities allow for differentiated behavioral patterns. As a consequence, it becomes possible for properties of movement to be specialized for detection of patches with more food, a larger scale information processing not present in the restricted model. Our results show that changes in decision making abilities can alter what kinds of pattern recognition are possible, eliminate an evolutionary trade-off and change the adaptive landscape.

  16. The Evolution of an Innovative Community-Engaged Health Navigator Program to Address Social Determinants of Health.

    PubMed

    Page-Reeves, Janet; Moffett, Maurice L; Steimel, Leah; Smith, Daryl T

    Health navigators and other types of community health workers (CHWs) have become recognized as essential components of quality care, and key for addressing health disparities owing to the complex health care services landscape presents almost insurmountable challenges for vulnerable individuals. Bernalillo County, New Mexico, has high rates of uninsurance, poverty, and food insecurity. The design of the Pathways to a Healthy Bernalillo County Program (BP) has evolved innovations that are unique in terms of program stability and security, expansive reach, and community capacity across six domains: sustainable public mechanism for program funding, involvement of community organizations in designing the program, expanded focus to address the broader social determinants of health with targeted outreach, an integrated, community-based implementation structure, an outcomes-based payment structure, and using an adaptive program design that actively incorporates navigators in the process. In 2008, the Pathways to a Healthy Bernalillo County Program (BP), located in the Albuquerque metropolitan area in central New Mexico, was established to provide navigation and support for the most vulnerable county residents. BP is funded through a 1% carve out of county mill levy funds. The pathways model is an outcome-based approach for health and social services coordination that uses culturally competent CHW as "navigators" trained to connect at-risk individuals to needed health and social services. One of the important innovations of the pathways approach is a shift in focus from merely providing discrete services to confirming healthy outcomes for the individual patient.

  17. Combining Open-domain and Biomedical Knowledge for Topic Recognition in Consumer Health Questions.

    PubMed

    Mrabet, Yassine; Kilicoglu, Halil; Roberts, Kirk; Demner-Fushman, Dina

    2016-01-01

    Determining the main topics in consumer health questions is a crucial step in their processing as it allows narrowing the search space to a specific semantic context. In this paper we propose a topic recognition approach based on biomedical and open-domain knowledge bases. In the first step of our method, we recognize named entities in consumer health questions using an unsupervised method that relies on a biomedical knowledge base, UMLS, and an open-domain knowledge base, DBpedia. In the next step, we cast topic recognition as a binary classification problem of deciding whether a named entity is the question topic or not. We evaluated our approach on a dataset from the National Library of Medicine (NLM), introduced in this paper, and another from the Genetic and Rare Disease Information Center (GARD). The combination of knowledge bases outperformed the results obtained by individual knowledge bases by up to 16.5% F1 and achieved state-of-the-art performance. Our results demonstrate that combining open-domain knowledge bases with biomedical knowledge bases can lead to a substantial improvement in understanding user-generated health content.

  18. Two perspectives on the needs of individuals bereaved by suicide.

    PubMed

    Gall, Terry Lynn; Henneberry, Jesse; Eyre, Melissa

    2014-01-01

    To qualitatively explore the needs of suicidally bereaved individuals, researchers interviewed 11 suicide bereaved individuals and 4 mental health workers. Common themes of bereaved persons included the suicide grief experience, coping, interpersonal domain, struggle with meaning, self-reflection, and moving forward. Mental health workers emphasized the nature of the helping relationship, the need to emotionally process the grief, the centrality of meaning making, importance of support groups, and the role of individual counseling. These 2 perspectives informed "best practices" for postvention (e.g., understanding the need for meaning-making while recognizing when to move on).

  19. Recognition of facial expressions and prosodic cues with graded emotional intensities in adults with Asperger syndrome.

    PubMed

    Doi, Hirokazu; Fujisawa, Takashi X; Kanai, Chieko; Ohta, Haruhisa; Yokoi, Hideki; Iwanami, Akira; Kato, Nobumasa; Shinohara, Kazuyuki

    2013-09-01

    This study investigated the ability of adults with Asperger syndrome to recognize emotional categories of facial expressions and emotional prosodies with graded emotional intensities. The individuals with Asperger syndrome showed poorer recognition performance for angry and sad expressions from both facial and vocal information. The group difference in facial expression recognition was prominent for stimuli with low or intermediate emotional intensities. In contrast to this, the individuals with Asperger syndrome exhibited lower recognition accuracy than typically-developed controls mainly for emotional prosody with high emotional intensity. In facial expression recognition, Asperger and control groups showed an inversion effect for all categories. The magnitude of this effect was less in the Asperger group for angry and sad expressions, presumably attributable to reduced recruitment of the configural mode of face processing. The individuals with Asperger syndrome outperformed the control participants in recognizing inverted sad expressions, indicating enhanced processing of local facial information representing sad emotion. These results suggest that the adults with Asperger syndrome rely on modality-specific strategies in emotion recognition from facial expression and prosodic information.

  20. Opting out or denying discrimination? How the framework of free choice in American society influences perceptions of gender inequality.

    PubMed

    Stephens, Nicole M; Levine, Cynthia S

    2011-10-01

    American women still confront workplace barriers (e.g., bias against mothers, inflexible policies) that hinder their advancement at the upper levels of organizations. However, most Americans fail to recognize that such gender barriers still exist. Focusing on mothers who have left the workforce, we propose that the prevalent American assumption that actions are a product of choice conceals workplace barriers by communicating that opportunities are equal and that behavior is free from contextual influence. Study 1 reveals that stay-at-home mothers who view their own workplace departure as an individual choice experience greater well-being but less often recognize workplace barriers and discrimination as a source of inequality than do mothers who do not view their workplace departure as an individual choice. Study 2 shows that merely exposing participants to a message that frames actions in terms of individual choice increases participants' belief that society provides equal opportunities and that gender discrimination no longer exists. By concealing the barriers that women still face in the workplace, this choice framework may hinder women's long-term advancement in society.

  1. Try to find me: social anxiety and peer first impressions.

    PubMed

    Aiken, Audrey; Human, Lauren J; Alden, Lynn E; Biesanz, Jeremy C

    2014-11-01

    Following initial interactions, some people are less willing to pursue ongoing contact with socially anxious individuals than with those who are not socially anxious. To better understand this process, we conducted two studies that examined peers' first impressions of target individuals. Unacquainted individuals (N=104 and 114) participated in round robin, unstructured interactions in groups of 3 to 10 and then rated each partner and themselves on items reflecting the Big Five personality dimensions. The ratings were analyzed according to Biesanz's (2010) social accuracy model of interpersonal perception, which distinguishes the positivity from the accuracy of social judgments. Study 1 revealed that perceivers did not view socially anxious targets more negatively or as less likable than non-socially anxious targets but were less able to recognize their unique personality features. Study 2 replicated those findings and indicated that perceivers' difficulties recognizing socially anxious targets' unique features were not due to negative biases in the socially anxious targets' self-ratings or to general psychological maladjustment. The findings are consistent with cognitive models, which underscore the role of self-concealment in social anxiety disorder. Copyright © 2014. Published by Elsevier Ltd.

  2. System for face recognition under expression variations of neutral-sampled individuals using recognized expression warping and a virtual expression-face database

    NASA Astrophysics Data System (ADS)

    Petpairote, Chayanut; Madarasmi, Suthep; Chamnongthai, Kosin

    2018-01-01

    The practical identification of individuals using facial recognition techniques requires the matching of faces with specific expressions to faces from a neutral face database. A method for facial recognition under varied expressions against neutral face samples of individuals via recognition of expression warping and the use of a virtual expression-face database is proposed. In this method, facial expressions are recognized and the input expression faces are classified into facial expression groups. To aid facial recognition, the virtual expression-face database is sorted into average facial-expression shapes and by coarse- and fine-featured facial textures. Wrinkle information is also employed in classification by using a process of masking to adjust input faces to match the expression-face database. We evaluate the performance of the proposed method using the CMU multi-PIE, Cohn-Kanade, and AR expression-face databases, and we find that it provides significantly improved results in terms of face recognition accuracy compared to conventional methods and is acceptable for facial recognition under expression variation.

  3. Carbohydrate Estimation by a Mobile Phone-Based System Versus Self-Estimations of Individuals With Type 1 Diabetes Mellitus: A Comparative Study.

    PubMed

    Rhyner, Daniel; Loher, Hannah; Dehais, Joachim; Anthimopoulos, Marios; Shevchik, Sergey; Botwey, Ransford Henry; Duke, David; Stettler, Christoph; Diem, Peter; Mougiakakou, Stavroula

    2016-05-11

    Diabetes mellitus is spreading throughout the world and diabetic individuals have been shown to often assess their food intake inaccurately; therefore, it is a matter of urgency to develop automated diet assessment tools. The recent availability of mobile phones with enhanced capabilities, together with the advances in computer vision, have permitted the development of image analysis apps for the automated assessment of meals. GoCARB is a mobile phone-based system designed to support individuals with type 1 diabetes during daily carbohydrate estimation. In a typical scenario, the user places a reference card next to the dish and acquires two images using a mobile phone. A series of computer vision modules detect the plate and automatically segment and recognize the different food items, while their 3D shape is reconstructed. Finally, the carbohydrate content is calculated by combining the volume of each food item with the nutritional information provided by the USDA Nutrient Database for Standard Reference. The main objective of this study is to assess the accuracy of the GoCARB prototype when used by individuals with type 1 diabetes and to compare it to their own performance in carbohydrate counting. In addition, the user experience and usability of the system is evaluated by questionnaires. The study was conducted at the Bern University Hospital, "Inselspital" (Bern, Switzerland) and involved 19 adult volunteers with type 1 diabetes, each participating once. Each study day, a total of six meals of broad diversity were taken from the hospital's restaurant and presented to the participants. The food items were weighed on a standard balance and the true amount of carbohydrate was calculated from the USDA nutrient database. Participants were asked to count the carbohydrate content of each meal independently and then by using GoCARB. At the end of each session, a questionnaire was completed to assess the user's experience with GoCARB. The mean absolute error was 27.89 (SD 38.20) grams of carbohydrate for the estimation of participants, whereas the corresponding value for the GoCARB system was 12.28 (SD 9.56) grams of carbohydrate, which was a significantly better performance ( P=.001). In 75.4% (86/114) of the meals, the GoCARB automatic segmentation was successful and 85.1% (291/342) of individual food items were successfully recognized. Most participants found GoCARB easy to use. This study indicates that the system is able to estimate, on average, the carbohydrate content of meals with higher accuracy than individuals with type 1 diabetes can. The participants thought the app was useful and easy to use. GoCARB seems to be a well-accepted supportive mHealth tool for the assessment of served-on-a-plate meals.

  4. Facial recognition in education system

    NASA Astrophysics Data System (ADS)

    Krithika, L. B.; Venkatesh, K.; Rathore, S.; Kumar, M. Harish

    2017-11-01

    Human beings exploit emotions comprehensively for conveying messages and their resolution. Emotion detection and face recognition can provide an interface between the individuals and technologies. The most successful applications of recognition analysis are recognition of faces. Many different techniques have been used to recognize the facial expressions and emotion detection handle varying poses. In this paper, we approach an efficient method to recognize the facial expressions to track face points and distances. This can automatically identify observer face movements and face expression in image. This can capture different aspects of emotion and facial expressions.

  5. Cross-cultural recognition of basic emotions through nonverbal emotional vocalizations

    PubMed Central

    Sauter, Disa A.; Eisner, Frank; Ekman, Paul; Scott, Sophie K.

    2010-01-01

    Emotional signals are crucial for sharing important information, with conspecifics, for example, to warn humans of danger. Humans use a range of different cues to communicate to others how they feel, including facial, vocal, and gestural signals. We examined the recognition of nonverbal emotional vocalizations, such as screams and laughs, across two dramatically different cultural groups. Western participants were compared to individuals from remote, culturally isolated Namibian villages. Vocalizations communicating the so-called “basic emotions” (anger, disgust, fear, joy, sadness, and surprise) were bidirectionally recognized. In contrast, a set of additional emotions was only recognized within, but not across, cultural boundaries. Our findings indicate that a number of primarily negative emotions have vocalizations that can be recognized across cultures, while most positive emotions are communicated with culture-specific signals. PMID:20133790

  6. Split-brain reveals separate but equal self-recognition in the two cerebral hemispheres.

    PubMed

    Uddin, Lucina Q; Rayman, Jan; Zaidel, Eran

    2005-09-01

    To assess the ability of the disconnected cerebral hemispheres to recognize images of the self, a split-brain patient (an individual who underwent complete cerebral commissurotomy to relieve intractable epilepsy) was tested using morphed self-face images presented to one visual hemifield (projecting to one hemisphere) at a time while making "self/other" judgments. The performance of the right and left hemispheres of this patient as assessed by a signal detection method was not significantly different, though a measure of bias did reveal hemispheric differences. The right and left hemispheres of this patient independently and equally possessed the ability to self-recognize, but only the right hemisphere could successfully recognize familiar others. This supports a modular concept of self-recognition and other-recognition, separately present in each cerebral hemisphere.

  7. Classification of pseudo pairs between nucleotide bases and amino acids by analysis of nucleotide-protein complexes.

    PubMed

    Kondo, Jiro; Westhof, Eric

    2011-10-01

    Nucleotide bases are recognized by amino acid residues in a variety of DNA/RNA binding and nucleotide binding proteins. In this study, a total of 446 crystal structures of nucleotide-protein complexes are analyzed manually and pseudo pairs together with single and bifurcated hydrogen bonds observed between bases and amino acids are classified and annotated. Only 5 of the 20 usual amino acid residues, Asn, Gln, Asp, Glu and Arg, are able to orient in a coplanar fashion in order to form pseudo pairs with nucleotide bases through two hydrogen bonds. The peptide backbone can also form pseudo pairs with nucleotide bases and presents a strong bias for binding to the adenine base. The Watson-Crick side of the nucleotide bases is the major interaction edge participating in such pseudo pairs. Pseudo pairs between the Watson-Crick edge of guanine and Asp are frequently observed. The Hoogsteen edge of the purine bases is a good discriminatory element in recognition of nucleotide bases by protein side chains through the pseudo pairing: the Hoogsteen edge of adenine is recognized by various amino acids while the Hoogsteen edge of guanine is only recognized by Arg. The sugar edge is rarely recognized by either the side-chain or peptide backbone of amino acid residues.

  8. Classification of pseudo pairs between nucleotide bases and amino acids by analysis of nucleotide–protein complexes

    PubMed Central

    Kondo, Jiro; Westhof, Eric

    2011-01-01

    Nucleotide bases are recognized by amino acid residues in a variety of DNA/RNA binding and nucleotide binding proteins. In this study, a total of 446 crystal structures of nucleotide–protein complexes are analyzed manually and pseudo pairs together with single and bifurcated hydrogen bonds observed between bases and amino acids are classified and annotated. Only 5 of the 20 usual amino acid residues, Asn, Gln, Asp, Glu and Arg, are able to orient in a coplanar fashion in order to form pseudo pairs with nucleotide bases through two hydrogen bonds. The peptide backbone can also form pseudo pairs with nucleotide bases and presents a strong bias for binding to the adenine base. The Watson–Crick side of the nucleotide bases is the major interaction edge participating in such pseudo pairs. Pseudo pairs between the Watson–Crick edge of guanine and Asp are frequently observed. The Hoogsteen edge of the purine bases is a good discriminatory element in recognition of nucleotide bases by protein side chains through the pseudo pairing: the Hoogsteen edge of adenine is recognized by various amino acids while the Hoogsteen edge of guanine is only recognized by Arg. The sugar edge is rarely recognized by either the side-chain or peptide backbone of amino acid residues. PMID:21737431

  9. Computing multiple aggregation levels and contextual features for road facilities recognition using mobile laser scanning data

    NASA Astrophysics Data System (ADS)

    Yang, Bisheng; Dong, Zhen; Liu, Yuan; Liang, Fuxun; Wang, Yongjun

    2017-04-01

    In recent years, updating the inventory of road infrastructures based on field work is labor intensive, time consuming, and costly. Fortunately, vehicle-based mobile laser scanning (MLS) systems provide an efficient solution to rapidly capture three-dimensional (3D) point clouds of road environments with high flexibility and precision. However, robust recognition of road facilities from huge volumes of 3D point clouds is still a challenging issue because of complicated and incomplete structures, occlusions and varied point densities. Most existing methods utilize point or object based features to recognize object candidates, and can only extract limited types of objects with a relatively low recognition rate, especially for incomplete and small objects. To overcome these drawbacks, this paper proposes a semantic labeling framework by combing multiple aggregation levels (point-segment-object) of features and contextual features to recognize road facilities, such as road surfaces, road boundaries, buildings, guardrails, street lamps, traffic signs, roadside-trees, power lines, and cars, for highway infrastructure inventory. The proposed method first identifies ground and non-ground points, and extracts road surfaces facilities from ground points. Non-ground points are segmented into individual candidate objects based on the proposed multi-rule region growing method. Then, the multiple aggregation levels of features and the contextual features (relative positions, relative directions, and spatial patterns) associated with each candidate object are calculated and fed into a SVM classifier to label the corresponding candidate object. The recognition performance of combining multiple aggregation levels and contextual features was compared with single level (point, segment, or object) based features using large-scale highway scene point clouds. Comparative studies demonstrated that the proposed semantic labeling framework significantly improves road facilities recognition precision (90.6%) and recall (91.2%), particularly for incomplete and small objects.

  10. EMERGING WATERBORNE PATHOGENS

    EPA Science Inventory

    Water treatment and wastewater disposal practices have reduced the death rate from waterborne illness. However, the number of individuals made ill, and the number of outbreaks of waterborne disease still fluctuates greatly. This is partly due to newly recognized disease agents,...

  11. The Attractions of Joined-Up Thinking.

    ERIC Educational Resources Information Center

    Payne, John

    1998-01-01

    Several British initiatives for workplace learning (University for Industry, Individual Learning Accounts, employee development) have common goals: widening participation, recognizing adult learning as a key to social inclusion, providing equal opportunities, and extending guidance provision for adults. (SK)

  12. Weathering the empire: meteorological research in the early British Straits Settlements.

    PubMed

    Williamson, Fiona

    2015-09-01

    This article explores meteorological interest and experimentation in the early history of the Straits Settlements. It centres on the establishment of an observatory in 1840s Singapore and examines the channels that linked the observatory to a global community of scientists, colonial officers and a reading public. It will argue that, although the value of overseas meteorological investigation was recognized by the British government, investment was piecemeal and progress in the field often relied on the commitment and enthusiasm of individuals. In the Straits Settlements, as elsewhere, these individuals were drawn from military or medical backgrounds, rather than trained as dedicated scientists. Despite this, meteorology was increasingly recognized as of fundamental importance to imperial interests. Thus this article connects meteorology with the history of science and empire more fully and examines how research undertaken in British dependencies is revealing of the operation of transnational networks in the exchange of scientific knowledge.

  13. Accurate Identification of Fear Facial Expressions Predicts Prosocial Behavior

    PubMed Central

    Marsh, Abigail A.; Kozak, Megan N.; Ambady, Nalini

    2009-01-01

    The fear facial expression is a distress cue that is associated with the provision of help and prosocial behavior. Prior psychiatric studies have found deficits in the recognition of this expression by individuals with antisocial tendencies. However, no prior study has shown accuracy for recognition of fear to predict actual prosocial or antisocial behavior in an experimental setting. In 3 studies, the authors tested the prediction that individuals who recognize fear more accurately will behave more prosocially. In Study 1, participants who identified fear more accurately also donated more money and time to a victim in a classic altruism paradigm. In Studies 2 and 3, participants’ ability to identify the fear expression predicted prosocial behavior in a novel task designed to control for confounding variables. In Study 3, accuracy for recognizing fear proved a better predictor of prosocial behavior than gender, mood, or scores on an empathy scale. PMID:17516803

  14. Suicidality in Body Dysmorphic Disorder

    PubMed Central

    Phillips, Katharine A.

    2008-01-01

    Suicidal ideation, suicide attempts, and completed suicide appear common in individuals with body dysmorphic disorder (BDD). Available evidence indicates that approximately 80% of individuals with BDD experience lifetime suicidal ideation and 24% to 28% have attempted suicide. Although data on completed suicide are limited and preliminary, the suicide rate appears markedly high. These findings underscore the importance of recognizing and effectively treating BDD. However, BDD is underrecognized in clinical settings even though it is relatively common and often presents to psychiatrists and other mental health practitioners, dermatologists, surgeons, and other physicians. This article reviews available evidence on suicidality in BDD and discusses how to recognize and diagnose this often secret disorder. Efficacious treatments for BDD, ie, serotonin reuptake inhibitors (SRIs) and cognitive-behavioral therapy, are also discussed. Although data are limited, it appears that SRIs often diminish suicidality in these patients. Additional research is greatly needed on suicidality rates, characteristics, correlates, risk factors, treatment, and prevention of suicidality in BDD. PMID:18449358

  15. Accurate identification of fear facial expressions predicts prosocial behavior.

    PubMed

    Marsh, Abigail A; Kozak, Megan N; Ambady, Nalini

    2007-05-01

    The fear facial expression is a distress cue that is associated with the provision of help and prosocial behavior. Prior psychiatric studies have found deficits in the recognition of this expression by individuals with antisocial tendencies. However, no prior study has shown accuracy for recognition of fear to predict actual prosocial or antisocial behavior in an experimental setting. In 3 studies, the authors tested the prediction that individuals who recognize fear more accurately will behave more prosocially. In Study 1, participants who identified fear more accurately also donated more money and time to a victim in a classic altruism paradigm. In Studies 2 and 3, participants' ability to identify the fear expression predicted prosocial behavior in a novel task designed to control for confounding variables. In Study 3, accuracy for recognizing fear proved a better predictor of prosocial behavior than gender, mood, or scores on an empathy scale.

  16. Recognition of emotion with temporal lobe epilepsy and asymmetrical amygdala damage.

    PubMed

    Fowler, Helen L; Baker, Gus A; Tipples, Jason; Hare, Dougal J; Keller, Simon; Chadwick, David W; Young, Andrew W

    2006-08-01

    Impairments in emotion recognition occur when there is bilateral damage to the amygdala. In this study, ability to recognize auditory and visual expressions of emotion was investigated in people with asymmetrical amygdala damage (AAD) and temporal lobe epilepsy (TLE). Recognition of five emotions was tested across three participant groups: those with right AAD and TLE, those with left AAD and TLE, and a comparison group. Four tasks were administered: recognition of emotion from facial expressions, sentences describing emotion-laden situations, nonverbal sounds, and prosody. Accuracy scores for each task and emotion were analysed, and no consistent overall effect of AAD on emotion recognition was found. However, some individual participants with AAD were significantly impaired at recognizing emotions, in both auditory and visual domains. The findings indicate that a minority of individuals with AAD have impairments in emotion recognition, but no evidence of specific impairments (e.g., visual or auditory) was found.

  17. Power in the role of the medical director: what it is and how to get more.

    PubMed

    Gabel, Stewart

    2011-05-01

    The formal leadership of mental health care organizations commonly resides in an executive director, who may or may not have had clinical training. The medical director is a psychiatrist who reports to the executive director. For some, this arrangement suggests that the medical director lacks or has lost power in the organization. This paper examines more specifically the types of power available to the medical director using French & Raven (1959) and Raven (2008) bases of power framework. The executive director/medical director relationship can be thought of as a relationship between individuals holding formal and informal power, respectively. Although medical directors lack formal or positional power, they potentially have and can gain more informal power based on their recognized clinical/medical expertise, their personal presence and an assertive involvement and focus on the organizational mission.

  18. A robust probabilistic collaborative representation based classification for multimodal biometrics

    NASA Astrophysics Data System (ADS)

    Zhang, Jing; Liu, Huanxi; Ding, Derui; Xiao, Jianli

    2018-04-01

    Most of the traditional biometric recognition systems perform recognition with a single biometric indicator. These systems have suffered noisy data, interclass variations, unacceptable error rates, forged identity, and so on. Due to these inherent problems, it is not valid that many researchers attempt to enhance the performance of unimodal biometric systems with single features. Thus, multimodal biometrics is investigated to reduce some of these defects. This paper proposes a new multimodal biometric recognition approach by fused faces and fingerprints. For more recognizable features, the proposed method extracts block local binary pattern features for all modalities, and then combines them into a single framework. For better classification, it employs the robust probabilistic collaborative representation based classifier to recognize individuals. Experimental results indicate that the proposed method has improved the recognition accuracy compared to the unimodal biometrics.

  19. Hijacked evidence-based medicine: stay the course and throw the pirates overboard.

    PubMed

    Ioannidis, John P A

    2017-04-01

    The article discusses a number of criticisms that have been raised against evidence-based medicine, such as focusing on benefits and ignoring adverse events; being interested in averages and ignoring the wide variability in individual risks and responsiveness; ignoring clinician-patient interaction and clinical judgement; leading to some sort of reductionism; and falling prey to corruption from conflicts of interest. I argue that none of these deficiencies are necessarily inherent to evidence-based medicine. In fact, work in evidence-based medicine has contributed a lot towards minimizing these deficiencies in medical research and medical care. However, evidence-based medicine is paying the price of its success: having become more widely recognized, it is manipulated and misused to support subverted or perverted agendas that are hijacking its reputation value. Sometimes the conflicts behind these agendas are so strong that one worries about whether the hijacking of evidence-based medicine is reversible. Nevertheless, evidence-based medicine is a valuable conceptual toolkit and it is worth to try to remove the biases of the pirates who have hijacked its ship. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. The history of atopic dermatitis.

    PubMed

    Kramer, Owen N; Strom, Mark A; Ladizinski, Barry; Lio, Peter A

    Fred Wise (1881-1950) and Marion Sulzberger (1895-1983) are often credited with introducing the term atopic dermatitis to dermatology in 1933. This definition was based on atopy, a term first created by Arthur Coca (1875-1959) and Robert Cooke (1880-1960) in 1923, when they recognized an association between allergic rhinitis and asthma. Despite its recent introduction into our medical lexicon, historical precursors of atopic dermatitis date back to at least as early as 69-140 ce. In this contribution, we highlight both the prominent individuals credited with shaping the disorder into our current interpretation and the suspected historical precursors of this disease and reported treatments. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. School-wide staff and faculty training in suicide risk awareness: successes and challenges.

    PubMed

    Walsh, Elaine; Hooven, Carole; Kronick, Barbara

    2013-02-01

    Rates of youth suicide and suicidal behavior remain high despite prevention efforts. Training high school personnel as gatekeepers is an important strategy. Training was implemented in a school district's five comprehensive high schools. Surveys were conducted before and after training sessions, which targeted all adults working at the high school. Two hundred thirty-seven individuals completed the pretest and/or posttest. Participants reported gains in knowledge, confidence, and feelings of competence in recognizing, approaching, and connecting distressed youth to school-based resources. Training was well received. Training is acceptable and appropriate for school personnel. Increasing the number of school personnel who participate in the training is challenging. © 2012 Wiley Periodicals, Inc.

  2. School-wide Staff and Faculty Training in Suicide Risk Awareness: Successes and Challenges

    PubMed Central

    Walsh, Elaine; Hooven, Carole; Kronick, Barbara

    2012-01-01

    Problem Rates of youth suicide and suicidal behavior remain high despite prevention efforts. Training high school personnel as gatekeepers is an important strategy. Methods Training was implemented in a school district’s 5 high schools. Surveys were conducted before and after training sessions, which targeted all adults working at the high school. Two-hundred thirty-seven individuals completed the pretest and/or posttest. Findings Participants reported gains in knowledge, confidence, and feelings of competence in recognizing, approaching, and connecting distressed youth to school-based resources. Training was well-received. Conclusion Training is acceptable and appropriate for school personnel. Increasing the number of school personnel who participate in the training is challenging. PMID:23351108

  3. Community-Associated Methicillin-Resistant Staphylococcus aureus Case Studies

    PubMed Central

    Sowash, Madeleine G.; Uhlemann, Anne-Catrin

    2014-01-01

    Over the past decade, the emergence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has changed the landscape of S. aureus infections around the globe. Initially recognized for its ability to cause disease in young and healthy individuals without healthcare exposures as well as for its distinct genotype and phenotype, this original description no longer fully encompasses the diversity of CA-MRSA as it continues to expand its niche. Using four case studies, we highlight a wide range of the clinical presentations and challenges of CA-MRSA. Based on these cases we further explore the globally polygenetic background of CA-MRSA with a special emphasis on generally less characterized populations. PMID:24085688

  4. Incorporating genomics into breast and prostate cancer screening: assessing the implications

    PubMed Central

    Chowdhury, Susmita; Dent, Tom; Pashayan, Nora; Hall, Alison; Lyratzopoulos, Georgios; Hallowell, Nina; Hall, Per; Pharoah, Paul; Burton, Hilary

    2013-01-01

    Individual risk prediction and stratification based on polygenic profiling may be useful in disease prevention. Risk-stratified population screening based on multiple factors including a polygenic risk profile has the potential to be more efficient than age-stratified screening. In this article, we summarize the implications of personalized screening for breast and prostate cancers. We report the opinions of multidisciplinary international experts who have explored the scientific, ethical, and logistical aspects of stratified screening. We have identified (i) the need to recognize the benefits and harms of personalized screening as compared with existing screening methods, (ii) that the use of genetic data highlights complex ethical issues including discrimination against high-risk individuals by insurers and employers and patient autonomy in relation to genetic testing of minors, (iii) the need for transparency and clear communication about risk scores, about harms and benefits, and about reasons for inclusion and exclusion from the risk-based screening process, and (iv) the need to develop new professional competences and to assess cost-effectiveness and acceptability of stratified screening programs before implementation. We conclude that health professionals and stakeholders need to consider the implications of incorporating genetic information in intervention strategies for health-care planning in the future. Genet Med 2013:15(6):423–432 PMID:23412607

  5. Managing Distributed Systems with Smart Subscriptions

    NASA Technical Reports Server (NTRS)

    Filman, Robert E.; Lee, Diana D.; Swanson, Keith (Technical Monitor)

    2000-01-01

    We describe an event-based, publish-and-subscribe mechanism based on using 'smart subscriptions' to recognize weakly-structured events. We present a hierarchy of subscription languages (propositional, predicate, temporal and agent) and algorithms for efficiently recognizing event matches. This mechanism has been applied to the management of distributed applications.

  6. Vermont Independent School Youth Needs Assessment Project. Final Report.

    ERIC Educational Resources Information Center

    Vermont State Department of Education, 2004

    2004-01-01

    This report contains information based on 47 interviews with administrators and educators from technical centers, approved and recognized independent schools, recognized schools, state operated facilities, state approved programs, and state approved tutorials in Vermont. The information in this report is based on self-reporting by individual…

  7. Low frequency of broadly neutralizing HIV antibodies during chronic infection even in quaternary epitope targeting antibodies containing large numbers of somatic mutations.

    PubMed

    Hicar, Mark D; Chen, Xuemin; Kalams, Spyros A; Sojar, Hakimuddin; Landucci, Gary; Forthal, Donald N; Spearman, Paul; Crowe, James E

    2016-02-01

    Neutralizing antibodies (Abs) are thought to be a critical component of an appropriate HIV vaccine response. It has been proposed that Abs recognizing conformationally dependent quaternary epitopes on the HIV envelope (Env) trimer may be necessary to neutralize diverse HIV strains. A number of recently described broadly neutralizing monoclonal Abs (mAbs) recognize complex and quaternary epitopes. Generally, many such Abs exhibit extensive numbers of somatic mutations and unique structural characteristics. We sought to characterize the native antibody (Ab) response against circulating HIV focusing on such conformational responses, without a prior selection based on neutralization. Using a capture system based on VLPs incorporating cleaved envelope protein, we identified a selection of B cells that produce quaternary epitope targeting Abs (QtAbs). Similar to a number of broadly neutralizing Abs, the Ab genes encoding these QtAbs showed extensive numbers of somatic mutations. However, when expressed as recombinant molecules, these Abs failed to neutralize virus or mediate ADCVI activity. Molecular analysis showed unusually high numbers of mutations in the Ab heavy chain framework 3 region of the variable genes. The analysis suggests that large numbers of somatic mutations occur in Ab genes encoding HIV Abs in chronically infected individuals in a non-directed, stochastic, manner. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. Understanding How Adolescents with Autism Respond to Facial Expressions in Virtual Reality Environments

    PubMed Central

    Bekele, Esubalew; Zheng, Zhi; Swanson, Amy; Crittendon, Julie; Warren, Zachary; Sarkar, Nilanjan

    2013-01-01

    Autism Spectrum Disorders (ASD) are characterized by atypical patterns of behaviors and impairments in social communication. Among the fundamental social impairments in the ASD population are challenges in appropriately recognizing and responding to facial expressions. Traditional intervention approaches often require intensive support and well-trained therapists to address core deficits, with many with ASD having tremendous difficulty accessing such care due to lack of available trained therapists as well as intervention costs. As a result, emerging technology such as virtual reality (VR) has the potential to offer useful technology-enabled intervention systems. In this paper, an innovative VR-based facial emotional expression presentation system was developed that allows monitoring of eye gaze and physiological signals related to emotion identification to explore new efficient therapeutic paradigms. A usability study of this new system involving ten adolescents with ASD and ten typically developing adolescents as a control group was performed. The eye tracking and physiological data were analyzed to determine intragroup and intergroup variations of gaze and physiological patterns. Performance data, eye tracking indices and physiological features indicated that there were differences in the way adolescents with ASD process and recognize emotional faces compared to their typically developing peers. These results will be used in the future for an online adaptive VR-based multimodal social interaction system to improve emotion recognition abilities of individuals with ASD. PMID:23428456

  9. Understanding how adolescents with autism respond to facial expressions in virtual reality environments.

    PubMed

    Bekele, Esubalew; Zheng, Zhi; Swanson, Amy; Crittendon, Julie; Warren, Zachary; Sarkar, Nilanjan

    2013-04-01

    Autism Spectrum Disorders (ASD) are characterized by atypical patterns of behaviors and impairments in social communication. Among the fundamental social impairments in the ASD population are challenges in appropriately recognizing and responding to facial expressions. Traditional intervention approaches often require intensive support and well-trained therapists to address core deficits, with many with ASD having tremendous difficulty accessing such care due to lack of available trained therapists as well as intervention costs. As a result, emerging technology such as virtual reality (VR) has the potential to offer useful technology-enabled intervention systems. In this paper, an innovative VR-based facial emotional expression presentation system was developed that allows monitoring of eye gaze and physiological signals related to emotion identification to explore new efficient therapeutic paradigms. A usability study of this new system involving ten adolescents with ASD and ten typically developing adolescents as a control group was performed. The eye tracking and physiological data were analyzed to determine intragroup and intergroup variations of gaze and physiological patterns. Performance data, eye tracking indices and physiological features indicated that there were differences in the way adolescents with ASD process and recognize emotional faces compared to their typically developing peers. These results will be used in the future for an online adaptive VR-based multimodal social interaction system to improve emotion recognition abilities of individuals with ASD.

  10. Visual working memory for global, object, and part-based information.

    PubMed

    Patterson, Michael D; Bly, Benjamin Martin; Porcelli, Anthony J; Rypma, Bart

    2007-06-01

    We investigated visual working memory for novel objects and parts of novel objects. After a delay period, participants showed strikingly more accurate performance recognizing a single whole object than the parts of that object. This bias to remember whole objects, rather than parts, persisted even when the division between parts was clearly defined and the parts were disconnected from each other so that, in order to remember the single whole object, the participants needed to mentally combine the parts. In addition, the bias was confirmed when the parts were divided by color. These experiments indicated that holistic perceptual-grouping biases are automatically used to organize storage in visual working memory. In addition, our results suggested that the bias was impervious to top-down consciously directed control, because when task demands were manipulated through instruction and catch trials, the participants still recognized whole objects more quickly and more accurately than their parts. This bias persisted even when the whole objects were novel and the parts were familiar. We propose that visual working memory representations depend primarily on the global configural properties of whole objects, rather than part-based representations, even when the parts themselves can be clearly perceived as individual objects. This global configural bias beneficially reduces memory load on a capacity-limited system operating in a complex visual environment, because fewer distinct items must be remembered.

  11. Psychodynamic Experience Enhances Recognition of Hidden Childhood Trauma

    PubMed Central

    Cohen, David; Milman, Daniel; Venturyera, Valérie; Falissard, Bruno

    2011-01-01

    Background Experimental psychology has only recently provided supporting evidence for Freud's and Janet's description of unconscious phenomena. Here, we aimed to assess whether specific abilities, such as personal psychodynamic experience, enhance the ability to recognize unconscious phenomena in peers – in other words, to better detect implicit knowledge related to individual self-experience. Methodology and Principal Findings First, we collected 14 videos from seven healthy adults who had experienced a sibling's cancer during childhood and seven matched controls. Subjects and controls were asked to give a 5-minute spontaneous free-associating speech following specific instructions created in order to activate a buffer zone between fantasy and reality. Then, 18 raters (three psychoanalysts, six medical students, three oncologists, three cognitive behavioral therapists and three individuals with the same experience of trauma) were randomly shown the videos and asked to blindly classify them according to whether the speaker had a sibling with cancer using a Likert scale. Using a permutation test, we found a significant association between group and recognition score (ANOVA: p = .0006). Psychoanalysts were able to recognize, above chance levels, healthy adults who had experienced sibling cancer during childhood without explicit knowledge of this history (Power = 88%; p = .002). In contrast, medical students, oncologists, cognitive behavioral therapists and individuals who had the same history of a sibling's cancer were unable to do so. Conclusion This experiment supports the view that implicit recognition of a subject's history depends on the rater's specific abilities. In the case of subjects who did have a sibling with cancer during childhood, psychoanalysts appear better able to recognize this particular history. PMID:21490974

  12. Academic consortium for the evaluation of computer-aided diagnosis (CADx) in mammography

    NASA Astrophysics Data System (ADS)

    Mun, Seong K.; Freedman, Matthew T.; Wu, Chris Y.; Lo, Shih-Chung B.; Floyd, Carey E., Jr.; Lo, Joseph Y.; Chan, Heang-Ping; Helvie, Mark A.; Petrick, Nicholas; Sahiner, Berkman; Wei, Datong; Chakraborty, Dev P.; Clarke, Laurence P.; Kallergi, Maria; Clark, Bob; Kim, Yongmin

    1995-04-01

    Computer aided diagnosis (CADx) is a promising technology for the detection of breast cancer in screening mammography. A number of different approaches have been developed for CADx research that have achieved significant levels of performance. Research teams now recognize the need for a careful and detailed evaluation study of approaches to accelerate the development of CADx, to make CADx more clinically relevant and to optimize the CADx algorithms based on unbiased evaluations. The results of such a comparative study may provide each of the participating teams with new insights into the optimization of their individual CADx algorithms. This consortium of experienced CADx researchers is working as a group to compare results of the algorithms and to optimize the performance of CADx algorithms by learning from each other. Each institution will be contributing an equal number of cases that will be collected under a standard protocol for case selection, truth determination, and data acquisition to establish a common and unbiased database for the evaluation study. An evaluation procedure for the comparison studies are being developed to analyze the results of individual algorithms for each of the test cases in the common database. Optimization of individual CADx algorithms can be made based on the comparison studies. The consortium effort is expected to accelerate the eventual clinical implementation of CADx algorithms at participating institutions.

  13. On the evolution of dispersal via heterogeneity in spatial connectivity

    PubMed Central

    Henriques-Silva, Renato; Boivin, Frédéric; Calcagno, Vincent; Urban, Mark C.; Peres-Neto, Pedro R.

    2015-01-01

    Dispersal has long been recognized as a mechanism that shapes many observed ecological and evolutionary processes. Thus, understanding the factors that promote its evolution remains a major goal in evolutionary ecology. Landscape connectivity may mediate the trade-off between the forces in favour of dispersal propensity (e.g. kin-competition, local extinction probability) and those against it (e.g. energetic or survival costs of dispersal). It remains, however, an open question how differing degrees of landscape connectivity may select for different dispersal strategies. We implemented an individual-based model to study the evolution of dispersal on landscapes that differed in the variance of connectivity across patches ranging from networks with all patches equally connected to highly heterogeneous networks. The parthenogenetic individuals dispersed based on a flexible logistic function of local abundance. Our results suggest, all else being equal, that landscapes differing in their connectivity patterns will select for different dispersal strategies and that these strategies confer a long-term fitness advantage to individuals at the regional scale. The strength of the selection will, however, vary across network types, being stronger on heterogeneous landscapes compared with the ones where all patches have equal connectivity. Our findings highlight how landscape connectivity can determine the evolution of dispersal strategies, which in turn affects how we think about important ecological dynamics such as metapopulation persistence and range expansion. PMID:25673685

  14. 26 CFR 601.502 - Recognized representative.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., territory, commonwealth, or the District of Columbia; (2) Certified public accountant. Any individual who is duly qualified to practice as a certified public accountant in any state, possession, territory... 10), concerning the practice of attorneys, certified public accountants, enrolled agents, enrolled...

  15. A QUANTITATIVE REAL-TIME PCR ASSAY FOR DETECTION OF CYCLOSPORA CAYETANESIS

    EPA Science Inventory

    Cyclospora cayetanensis, a coccidian parasite with a direct fecal-oral life cycle, has become recognized world-wide as an emerging pathogen in both immunocompromised and immunocompetent individuals. Clinical manifestations include prolonged diarrhea, nausea, abdominal cramps, an...

  16. Beacon- and Schema-Based Method for Recognizing Algorithms from Students' Source Code

    ERIC Educational Resources Information Center

    Taherkhani, Ahmad; Malmi, Lauri

    2013-01-01

    In this paper, we present a method for recognizing algorithms from students programming submissions coded in Java. The method is based on the concept of "programming schemas" and "beacons". Schemas are high-level programming knowledge with detailed knowledge abstracted out, and beacons are statements that imply specific…

  17. Towards a Rational Design of an Asymptomatic Clinical Herpes Vaccine: The Old, the New, and the Unknown

    PubMed Central

    Alami Chentoufi, Aziz; Kritzer, Elizabeth; Yu, David M.; Nesburn, Anthony B.; BenMohamed, Lbachir

    2012-01-01

    The best hope of controlling the herpes simplex virus type 1 and type 2 (HSV-1 and HSV-2) pandemic is the development of an effective vaccine. However, in spite of several clinical trials, starting as early as 1920s, no vaccine has been proven sufficiently safe and efficient to warrant commercial development. In recent years, great strides in cellular and molecular immunology have stimulated creative efforts in controlling herpes infection and disease. However, before moving towards new vaccine strategy, it is necessary to answer two fundamental questions: (i) why past herpes vaccines have failed? (ii) Why the majority of HSV seropositive individuals (i.e., asymptomatic individuals) are naturally “protected” exhibiting few or no recurrent clinical disease, while other HSV seropositive individuals (i.e., symptomatic individuals) have frequent ocular, orofacial, and/or genital herpes clinical episodes? We recently discovered several discrete sets of HSV-1 symptomatic and asymptomatic epitopes recognized by CD4+ and CD8+ T cells from seropositive symptomatic versus asymptomatic individuals. These asymptomatic epitopes will provide a solid foundation for the development of novel herpes epitope-based vaccine strategy. Here we provide a brief overview of past clinical vaccine trials, outline current progress towards developing a new generation “asymptomatic” clinical herpes vaccines, and discuss future mucosal “asymptomatic” prime-boost vaccines that could optimize local protective immunity. PMID:22548113

  18. Individual odor recognition in birds: an endogenous olfactory signature on petrels' feathers?

    PubMed

    Bonadonna, Francesco; Miguel, Eve; Grosbois, Vladimir; Jouventin, Pierre; Bessiere, Jean-Marie

    2007-09-01

    A growing body of evidence indicates that odors are used in individual, sexual, and species recognition in vertebrates, and may be reliable signals of quality and compatibility. Petrels are seabirds that exhibit an acute sense of smell. During the breeding period, many species of petrels live in dense colonies on small oceanic islands and form pairs that use individual underground burrows. Mates alternate between parental duties and foraging trips at sea. Returning from the ocean at night (to avoid bird predators), petrels must find their nest burrow. Antarctic prions, Pachyptila desolata, are thought to identify their nest by recognizing their partner's odor, suggesting the existence of an individual odor signature. We used gas chromatography and mass spectrometry to analyze extracts obtained from the feathers of 13 birds. The chemical profile of a single bird was more similar to itself, from year to year, than to that of any other bird. The profile contained up to a hundred volatile lipids, but the odor signature may be based on the presence or absence of a few specific compounds. Our results show that the odor signature in Antarctic prions is probably endogenous, suggesting that in some species of petrels it may broadcast compatibility and quality of potential mates.

  19. DNA fingerprinting in zoology: past, present, future.

    PubMed

    Chambers, Geoffrey K; Curtis, Caitlin; Millar, Craig D; Huynen, Leon; Lambert, David M

    2014-02-03

    In 1962, Thomas Kuhn famously argued that the progress of scientific knowledge results from periodic 'paradigm shifts' during a period of crisis in which new ideas dramatically change the status quo. Although this is generally true, Alec Jeffreys' identification of hypervariable repeat motifs in the human beta-globin gene, and the subsequent development of a technology known now as 'DNA fingerprinting', also resulted in a dramatic shift in the life sciences, particularly in ecology, evolutionary biology, and forensics. The variation Jeffreys recognized has been used to identify individuals from tissue samples of not just humans, but also of many animal species. In addition, the technology has been used to determine the sex of individuals, as well as paternity/maternity and close kinship. We review a broad range of such studies involving a wide diversity of animal species. For individual researchers, Jeffreys' invention resulted in many ecologists and evolutionary biologists being given the opportunity to develop skills in molecular biology to augment their whole organism focus. Few developments in science, even among the subsequent genome discoveries of the 21st century, have the same wide-reaching significance. Even the later development of PCR-based genotyping of individuals using microsatellite repeats sequences, and their use in determining multiple paternity, is conceptually rooted in Alec Jeffreys' pioneering work.

  20. Recognition of three epitopic regions on invasion plasmid antigen C by immune sera of rhesus monkeys infected with Shigella flexneri 2a.

    PubMed Central

    Turbyfill, K R; Joseph, S W; Oaks, E V

    1995-01-01

    The invasive ability of Shigella spp. is correlated with the expression of several plasmid-encoded proteins, including invasion plasmid antigen C (IpaC). By characterizing the antigenic structure of IpaC with monoclonal antibodies and convalescent-phase sera, it may be possible to determine the physical location of specific epitopes as well as the involvement of epitopes in a protective immune response or the host's susceptibility to disease. By using overlapping octameric synthetic peptides, which together represent the entire IpaC protein, the precise linear sequence of four surface-exposed epitopes was defined for four IpaC monoclonal antibodies. Furthermore, 17 unique peptide epitopes of IpaC were mapped by using 9-day-postinfection serum samples from 13 rhesus monkeys challenged with Shigella flexneri 2a. Each individual recognized a somewhat different array of IpaC peptide epitopes after infection with shigellae. However, the epitopes were clustered within three regions of the protein: region I (between amino acid residues 1 and 61), region II (between amino acid residues 177 and 258), and region III (between amino acid residues 298 and 307). Region II was recognized by 92% of S. flexneri-infected individuals and was considered to be a highly immunogenic region. Animals asymptomatic for shigellosis after challenge with S. flexneri recognized peptide epitopes within all three epitopic regions of IpaC, whereas symptomatic animals recognized peptides in only one or two of the epitopic regions. Antibody from monkeys challenged with S. sonnei recognized IpaC peptide epitopes which fell within and outside the three S. flexneri epitopic regions. While numerous potential epitopes exist on the IpaC protein, the identification of three regions in which epitopes are clustered suggests that these regions are significant with respect to the immune response and to subsequent pathogenesis postinfection. PMID:7558301

  1. Using program evaluation to support knowledge translation in an interprofessional primary care team: a case study.

    PubMed

    Donnelly, Catherine; Shulha, Lyn; Klinger, Don; Letts, Lori

    2016-10-06

    Evaluation is a fundamental component in building quality primary care and is ideally situated to support individual, team and organizational learning by offering an accessible form of participatory inquiry. The evaluation literature has begun to recognize the unique features of KT evaluations and has described attributes to consider when evaluating KT activities. While both disciplines have focused on the evaluation of KT activities neither has explored the role of evaluation in KT. The purpose of the paper is to examine how participation in program evaluation can support KT in a primary care setting. A mixed methods case study design was used, where evaluation was conceptualized as a change process and intervention. A Memory Clinic at an interprofessional primary care clinic was the setting in which the study was conducted. An evaluation framework, Pathways of Influence provided the theoretical foundation to understand how program evaluation can facilitate the translation of knowledge at the level of the individual, inter-personal (Memory Clinic team) and the organization. Data collection included questionnaires, interviews, evaluation log and document analysis. Questionnaires and interviews were administered both before and after the evaluation: Pattern matching was used to analyze the data based on predetermined propositions. Individuals gained program knowledge that resulted in changes to both individual and program practices. One of the key themes was the importance clinicians placed on local, program based knowledge. The evaluation had less influence on the broader health organization. Program evaluation facilitated individual, team and organizational learning. The use of evaluation to support KT is ideally suited to a primary care setting by offering relevant and applicable knowledge to primary care team members while being sensitive to local context.

  2. Explicit and Implicit Components of the Emotional Processing in Non-organic Vision Loss: Behavioral Evidence About the Role of Fear in Functional Blindness

    PubMed Central

    Scarpina, Federica; Melzi, Lisa; Castelnuovo, Gianluca; Mauro, Alessandro; Marzoli, Stefania B.; Molinari, Enrico

    2018-01-01

    Non-organic vision loss (NOVL), a functional partial or global vision loss, might be considered a manifestation of conversion disorder. The few previous studies focused on investigating the relationship between cerebral activity and subjective symptoms in NOVL; however, the emotional processing is still neglected. In the present case-controls study, we investigated the capability of two individuals diagnosed with NOVL to recognize implicitly the emotions of fear and anger; this was assessed through a facial emotion recognition task based on the redundant target effect. In addition, the level of alexithymia was measured by asking them to judge explicitly their ability to identify and describe emotions. Both individuals showed selective difficulties in recognizing the emotion of fear when their performance was contrasted with a matched control sample; they also mislabeled other emotional stimuli, judging them as fearful, when they were not. However, they did not report alexithymia when measured using a standard questionnaire. This preliminary investigation reports a mismatch between the implicit (i.e., the behavior in the experimental paradigm) and the explicit (i.e., the subjective evaluation of one’s own emotional capability) components of the emotional processing in NOVL. Moreover, fear seems to represent a critical emotion in this condition, as has been reported in other psychiatric disorders. However, possible difficulties in the emotional processing of fear would emerge only when they are inferred from an implicit behavior, instead of a subjective evaluation of one’s own emotional processing capability. PMID:29692751

  3. Screening for cognitive impairment in older individuals. Validation study of a computer-based test.

    PubMed

    Green, R C; Green, J; Harrison, J M; Kutner, M H

    1994-08-01

    This study examined the validity of a computer-based cognitive test that was recently designed to screen the elderly for cognitive impairment. Criterion-related validity was examined by comparing test scores of impaired patients and normal control subjects. Construct-related validity was computed through correlations between computer-based subtests and related conventional neuropsychological subtests. University center for memory disorders. Fifty-two patients with mild cognitive impairment by strict clinical criteria and 50 unimpaired, age- and education-matched control subjects. Control subjects were rigorously screened by neurological, neuropsychological, imaging, and electrophysiological criteria to identify and exclude individuals with occult abnormalities. Using a cut-off total score of 126, this computer-based instrument had a sensitivity of 0.83 and a specificity of 0.96. Using a prevalence estimate of 10%, predictive values, positive and negative, were 0.70 and 0.96, respectively. Computer-based subtests correlated significantly with conventional neuropsychological tests measuring similar cognitive domains. Thirteen (17.8%) of 73 volunteers with normal medical histories were excluded from the control group, with unsuspected abnormalities on standard neuropsychological tests, electroencephalograms, or magnetic resonance imaging scans. Computer-based testing is a valid screening methodology for the detection of mild cognitive impairment in the elderly, although this particular test has important limitations. Broader applications of computer-based testing will require extensive population-based validation. Future studies should recognize that normal control subjects without a history of disease who are typically used in validation studies may have a high incidence of unsuspected abnormalities on neurodiagnostic studies.

  4. Is a Pink Cow Still a Cow? Individual Differences in Toddlers' Vocabulary Knowledge and Lexical Representations.

    PubMed

    Perry, Lynn K; Saffran, Jenny R

    2017-05-01

    When a toddler knows a word, what does she actually know? Many categories have multiple relevant properties; for example, shape and color are relevant to membership in the category banana. How do toddlers prioritize these properties when recognizing familiar words, and are there systematic differences among children? In this study, toddlers viewed pairs of objects associated with prototypical colors. On some trials, objects were typically colored (e.g., Holstein cow and pink pig); on other trials, colors were switched (e.g., pink cow and Holstein-patterned pig). On each trial, toddlers were directed to find a target object. Overall, recognition was disrupted when colors were switched, as measured by eye movements. Moreover, individual differences in vocabularies predicted recognition differences: Toddlers who say fewer shape-based words were more disrupted by color switches. "Knowing" a word may not mean the same thing for all toddlers; different toddlers prioritize different facets of familiar objects in their lexical representations. Copyright © 2016 Cognitive Science Society, Inc.

  5. Olfactory cues associated with the major histocompatibility complex.

    PubMed

    Eggert, F; Müller-Ruchholtz, W; Ferstl, R

    Besides its immunological function of self/non-self discrimination the major histocompatibility complex (MHC) has been recognized as a possible source of individual specific body odors. Dating back to speculations on the role of the extraordinary polymorphism of the MHC as background of an individual chemosensory identity and to early observations of MHC-dependent mate choice in inbred strains of mice, systematic experimental studies revealed a first evidence for H-2 related body odors in this species. Meanwhile a large number of animal studies with rodents and a series of field studies and experiments with humans have extended our knowledge of MHC-related odor signals and substantiated the hypothesis of immunogenetic associated odor types. These results suggest that the most prominent feature of the MHC, its extraordinary genetic diversity, seems in part to be selectively maintained by behavioral mechanisms which operate in contemporary natural populations. The high degree of heterozygosity found in natural populations of most species seems to be promoted by non-disease-based selection such as mating preferences and selective block of pregnancy.

  6. Can the identity of a behavior setting be perceived through patterns of joint action? An investigation of place perception.

    PubMed

    Heft, Harry; Hoch, Justine; Edmunds, Trent; Weeks, Jillian

    2014-10-13

    "Behavior settings" are generated by joint actions of individuals in conjunction with the milieu features (or affordances) that are available. The reported research explores the hypothesis that the identity or meaning of a behavior setting can be perceived by means of the patterns of action collectively generated by the setting's participants. A set of computer animations was created based on detailed observation of activities in everyday settings. Three experiments were conducted to assess whether perceivers could extract "structure from motion" (in this case, collective actions) that was specific to the particular behavior setting displayed by way of the animations. Two experiments assessed whether individuals could accurately perceive the identity of the behavior settings with such displays, and a third experiment indirectly examined this possibility by evaluating whether setting possibilities and constraints were recognized. The results offered some support for the hypothesis, and suggested several refinements in how to conceptualize a typology of behavior settings. An ecological approach to place perception is also discussed.

  7. Deprivation Indices, Population Health and Geography: An Evaluation of the Spatial Effectiveness of Indices at Multiple Scales

    PubMed Central

    Bell, Nathaniel; Dunn, James R.; Oliver, Lisa

    2007-01-01

    Area-based deprivation indices (ABDIs) have become a common tool with which to investigate the patterns and magnitude of socioeconomic inequalities in health. ABDIs are also used as a proxy for individual socioeconomic status. Despite their widespread use, comparably less attention has been focused on their geographic variability and practical concerns surrounding the Modifiable Area Unit Problem (MAUP) than on the individual attributes that make up the indices. Although scale is increasingly recognized as an important factor in interpreting mapped results among population health researchers, less attention has been paid specifically to ABDI and scale. In this paper, we highlight the effect of scale on indices by mapping ABDIs at multiple census scales in an urban area. In addition, we compare self-rated health data from the Canadian Community Health Survey with ABDIs at two census scales. The results of our analysis confirm the influence of spatial extent and scale on mapping population health—with potential implications for health policy implementation and resource distribution. PMID:17447145

  8. The application of biological motion research: biometrics, sport, and the military.

    PubMed

    Steel, Kylie; Ellem, Eathan; Baxter, David

    2015-02-01

    The body of research that examines the perception of biological motion is extensive and explores the factors that are perceived from biological motion and how this information is processed. This research demonstrates that individuals are able to use relative (temporal and spatial) information from a person's movement to recognize factors, including gender, age, deception, emotion, intention, and action. The research also demonstrates that movement presents idiosyncratic properties that allow individual discrimination, thus providing the basis for significant exploration in the domain of biometrics and social signal processing. Medical forensics, safety garments, and victim selection domains also have provided a history of research on the perception of biological motion applications; however, a number of additional domains present opportunities for application that have not been explored in depth. Therefore, the purpose of this paper is to present an overview of the current applications of biological motion-based research and to propose a number of areas where biological motion research, specific to recognition, could be applied in the future.

  9. Training echo state networks for rotation-invariant bone marrow cell classification.

    PubMed

    Kainz, Philipp; Burgsteiner, Harald; Asslaber, Martin; Ahammer, Helmut

    2017-01-01

    The main principle of diagnostic pathology is the reliable interpretation of individual cells in context of the tissue architecture. Especially a confident examination of bone marrow specimen is dependent on a valid classification of myeloid cells. In this work, we propose a novel rotation-invariant learning scheme for multi-class echo state networks (ESNs), which achieves very high performance in automated bone marrow cell classification. Based on representing static images as temporal sequence of rotations, we show how ESNs robustly recognize cells of arbitrary rotations by taking advantage of their short-term memory capacity. The performance of our approach is compared to a classification random forest that learns rotation-invariance in a conventional way by exhaustively training on multiple rotations of individual samples. The methods were evaluated on a human bone marrow image database consisting of granulopoietic and erythropoietic cells in different maturation stages. Our ESN approach to cell classification does not rely on segmentation of cells or manual feature extraction and can therefore directly be applied to image data.

  10. Multivariable Sensors for Ubiquitous Monitoring of Gases in the Era of Internet of Things and Industrial Internet.

    PubMed

    Potyrailo, Radislav A

    2016-10-12

    Modern gas monitoring scenarios for medical diagnostics, environmental surveillance, industrial safety, and other applications demand new sensing capabilities. This Review provides analysis of development of new generation of gas sensors based on the multivariable response principles. Design criteria of these individual sensors involve a sensing material with multiresponse mechanisms to different gases and a multivariable transducer with independent outputs to recognize these different gas responses. These new sensors quantify individual components in mixtures, reject interferences, and offer more stable response over sensor arrays. Such performance is attractive when selectivity advantages of classic gas chromatography, ion mobility, and mass spectrometry instruments are canceled by requirements for no consumables, low power, low cost, and unobtrusive form factors for Internet of Things, Industrial Internet, and other applications. This Review is concluded with a perspective for future needs in fundamental and applied aspects of gas sensing and with the 2025 roadmap for ubiquitous gas monitoring.

  11. Abnormal Grief: Should We Consider a More Patient-Centered Approach?

    PubMed

    Moayedoddin, Babak; Markowitz, John C

    2015-01-01

    Grief, the psychological reaction to the loss of a significant other, varies complexly in its cause, experience, evolution, and prognosis. Although most bereaved individuals experience a normal grieving process, some develop complicated grief (CG) or major depressive disorder (MDD). The DSM-5, which controversially altered the nosology, recognizes grief-related major depression (GRMD) as a diagnostic subtype if a patient meets MDD criteria two weeks post bereavement. The (DSM-5) tries to distinguish between grief and MDD, but remains a symptom-based, centered approach to grief that is not patient centered. This article reviews grief in its normal and abnormal dimensions. Using an illustrative clinical case in which interpersonal psychotherapy (IPT) was employed, we discuss the need for a more patient-centered approach to treating abnormal grief, considering the patient's personal history, perceptions, experiences of bereavement, and interpersonal environment. Clinical studies need to better identify subgroups of individuals susceptible to abnormal grief and to evaluate their response to early interventions.

  12. Detecting Gunshots Using Wearable Accelerometers

    PubMed Central

    Loeffler, Charles E.

    2014-01-01

    Gun violence continues to be a staggering and seemingly intractable issue in many communities. The prevalence of gun violence among the sub-population of individuals under court-ordered community supervision provides an opportunity for intervention using remote monitoring technology. Existing monitoring systems rely heavily on location-based monitoring methods, which have incomplete geographic coverage and do not provide information on illegal firearm use. This paper presents the first results demonstrating the feasibility of using wearable inertial sensors to recognize wrist movements and other signals corresponding to firearm usage. Data were collected from accelerometers worn on the wrists of subjects shooting a number of different firearms, conducting routine daily activities, and participating in activities and tasks that could be potentially confused with firearm discharges. A training sample was used to construct a combined detector and classifier for individual gunshots, which achieved a classification accuracy of 99.4 percent when tested against a hold-out sample of observations. These results suggest the feasibility of using inexpensive wearable sensors to detect firearm discharges. PMID:25184416

  13. Fatty acid metabolism in breast cancer subtypes

    PubMed Central

    Monaco, Marie E.

    2017-01-01

    Dysregulation of fatty acid metabolism is recognized as a component of malignant transformation in many different cancers, including breast; yet the potential for targeting this pathway for prevention and/or treatment of cancer remains unrealized. Evidence indicates that proteins involved in both synthesis and oxidation of fatty acids play a pivotal role in the proliferation, migration and invasion of breast cancer cells. The following essay summarizes data implicating specific fatty acid metabolic enzymes in the genesis and progression of breast cancer, and further categorizes the relevance of specific metabolic pathways to individual intrinsic molecular subtypes of breast cancer. Based on mRNA expression data, the less aggressive luminal subtypes appear to rely on a balance between de novo fatty acid synthesis and oxidation as sources for both biomass and energy requirements, while basal-like, receptor negative subtypes overexpress genes involved in the utilization of exogenous fatty acids. With these differences in mind, treatments may need to be tailored to individual subtypes. PMID:28412757

  14. Geographic Health Information Systems: A Platform To Support The ‘Triple Aim’

    PubMed Central

    Miranda, Marie Lynn; Ferranti, Jeffrey; Strauss, Benjamin; Neelon, Brian; Califf, Robert M.

    2014-01-01

    Despite the rapid growth of electronic health data, most data systems do not connect individual patient records to data sets from outside the health care delivery system. These isolated data systems cannot support efforts to recognize or address how the physical and environmental context of each patient influences health choices and health outcomes. In this article we describe how a geographic health information system in Durham, North Carolina, links health system and social and environmental data via shared geography to provide a multidimensional understanding of individual and community health status and vulnerabilities. Geographic health information systems can be useful in supporting the Institute for Healthcare Improvement’s Triple Aim Initiative to improve the experience of care, improve the health of populations, and reduce per capita costs of health care. A geographic health information system can also provide a comprehensive information base for community health assessment and intervention for accountable care that includes the entire population of a geographic area. PMID:24019366

  15. Origins of modern premedical education.

    PubMed

    Fishbein, R H

    2001-05-01

    The author reviews the contributions of those individuals and major academic and professional organizations responsible for the development of the modern concepts of the premedical education of a physician. The late 19th century gave rise to scientifically-based medical education in U.S. medical education. It followed that this new emphasis, in medical schools, on laboratory investigation of disease processes demanded a sound introduction to the natural sciences by those who would be candidates for this type of challenging education. Starting with a vocal few, the message gradually was received throughout the country that a properly schooled physician must have the equivalent of a broad baccalaureate education in the natural sciences as well as in the traditional humanities. This essential was recognized by a small nucleus of individuals responsible for the creation of The Johns Hopkins University in 1876 and its school of medicine in 1893; the group was led by the university's first president, Daniel Coit GILMAN: Almost simultaneously other established academic institutions incorporated similar changes and a new era began.

  16. Detecting gunshots using wearable accelerometers.

    PubMed

    Loeffler, Charles E

    2014-01-01

    Gun violence continues to be a staggering and seemingly intractable issue in many communities. The prevalence of gun violence among the sub-population of individuals under court-ordered community supervision provides an opportunity for intervention using remote monitoring technology. Existing monitoring systems rely heavily on location-based monitoring methods, which have incomplete geographic coverage and do not provide information on illegal firearm use. This paper presents the first results demonstrating the feasibility of using wearable inertial sensors to recognize wrist movements and other signals corresponding to firearm usage. Data were collected from accelerometers worn on the wrists of subjects shooting a number of different firearms, conducting routine daily activities, and participating in activities and tasks that could be potentially confused with firearm discharges. A training sample was used to construct a combined detector and classifier for individual gunshots, which achieved a classification accuracy of 99.4 percent when tested against a hold-out sample of observations. These results suggest the feasibility of using inexpensive wearable sensors to detect firearm discharges.

  17. Upholding pregnant women's right to life.

    PubMed

    Cook, Rebecca J; Dickens, Bernard M

    2012-04-01

    Recent decisions of the Committee on the Elimination of Discrimination against Women (CEDAW), the Inter-American Court of Human Rights, and the High Court of Delhi have shown how the pregnancy-related deaths of individual women have been bases on which these authoritative tribunals have held Brazil, Paraguay, and India respectively accountable for avoidable maternal mortality not only in these cases, but also among their populations more generally. The right to life is the most fundamental of women's human rights, recognized in international human rights treaties and national laws. Failure of governments to apply their resources adequately to address, respect, and protect this right violates the law of human rights. These cases show, however, that governments may fail to allocate adequate resources to women's survival of pregnancy. Tribunals can build on the failures in individual cases to set standards of performance to which governments will legally be held to achieve safe motherhood. Copyright © 2012 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

  18. Occupational balance: exploring the relationships among daily occupations and their influence on well-being.

    PubMed

    Backman, Catherine L

    2004-10-01

    In this lecture, I have reviewed theoretical discussions and definitions of occupational balance, findings from selected studies, and highlighted some methods for measuring aspects of occupational balance. Are any of these ideas directly applicable to occupational therapy practice, education and research? Consider the hassles of everyday life, and add the complicating factors of illness, injury, disability, and limited income. Life, and the pursuit of necessary, desirable and obligatory occupations, can become overwhelming. Given that occupational therapists aim to enable individuals, regardless of ability, to successfully engage in a range of occupations, the answer to the question is yes. Furthering our understanding of occupational balance can improve our ability to serve individual clients and society. In 2001, Fearing stated in her Muriel Driver Memorial Lecture: We will not only recognize and value the skill of maintaining balance, our own and that of our clients, but we will live it. Balance will not be viewed as a set of scales that has equal parts such as work on one side and play on the other but rather the kind of balance that comes from being centred so that we act from a stable base. From that stable base, we will gain a keen sensitivity to rhythm--knowing when to move and when to let go. (Fearing, 2001 pp. 214-215) Perhaps these reflections have added a little coherence to the study of occupational balance. Occupational balance is a relative state, recognizable by a happy or pleasant integration of life activities and demands. There are indicators of imbalance, more so than tangible ways to measure it, and once recognized occupational therapists have the strategies to help restore a sense of occupational balance. Given our collective history and skill in client-centred practice, occupational therapists are capable of both advancing this line of inquiry and attaining occupational balance for ourselves and our clients.

  19. Bayesian multivariate Poisson abundance models for T-cell receptor data.

    PubMed

    Greene, Joshua; Birtwistle, Marc R; Ignatowicz, Leszek; Rempala, Grzegorz A

    2013-06-07

    A major feature of an adaptive immune system is its ability to generate B- and T-cell clones capable of recognizing and neutralizing specific antigens. These clones recognize antigens with the help of the surface molecules, called antigen receptors, acquired individually during the clonal development process. In order to ensure a response to a broad range of antigens, the number of different receptor molecules is extremely large, resulting in a huge clonal diversity of both B- and T-cell receptor populations and making their experimental comparisons statistically challenging. To facilitate such comparisons, we propose a flexible parametric model of multivariate count data and illustrate its use in a simultaneous analysis of multiple antigen receptor populations derived from mammalian T-cells. The model relies on a representation of the observed receptor counts as a multivariate Poisson abundance mixture (m PAM). A Bayesian parameter fitting procedure is proposed, based on the complete posterior likelihood, rather than the conditional one used typically in similar settings. The new procedure is shown to be considerably more efficient than its conditional counterpart (as measured by the Fisher information) in the regions of m PAM parameter space relevant to model T-cell data. Copyright © 2013 Elsevier Ltd. All rights reserved.

  20. Listing Occupational Carcinogens

    PubMed Central

    Siemiatycki, Jack; Richardson, Lesley; Straif, Kurt; Latreille, Benoit; Lakhani, Ramzan; Campbell, Sally; Rousseau, Marie-Claude; Boffetta, Paolo

    2004-01-01

    The occupational environment has been a most fruitful one for investigating the etiology of human cancer. Many recognized human carcinogens are occupational carcinogens. There is a large volume of epidemiologic and experimental data concerning cancer risks in different work environments. It is important to synthesize this information for both scientific and public health purposes. Various organizations and individuals have published lists of occupational carcinogens. However, such lists have been limited by unclear criteria for which recognized carcinogens should be considered occupational carcinogens, and by inconsistent and incomplete information on the occupations and industries in which the carcinogenic substances may be found and on their target sites of cancer. Based largely on the evaluations published by the International Agency for Research on Cancer, and augmented with additional information, the present article represents an attempt to summarize, in tabular form, current knowledge on occupational carcinogens, the occupations and industries in which they are found, and their target organs. We have considered 28 agents as definite occupational carcinogens, 27 agents as probable occupational carcinogens, and 113 agents as possible occupational carcinogens. These tables should be useful for regulatory or preventive purposes and for scientific purposes in research priority setting and in understanding carcinogenesis. PMID:15531427

  1. Novel Compound Heterozygous Mutations Expand the Recognized Phenotypes of FARS2-Linked Disease.

    PubMed

    Walker, Melissa A; Mohler, Kyle P; Hopkins, Kyle W; Oakley, Derek H; Sweetser, David A; Ibba, Michael; Frosch, Matthew P; Thibert, Ronald L

    2016-08-01

    Mutations in mitochondrial aminoacyl-tRNA synthetases are an increasingly recognized cause of human diseases, often arising in individuals with compound heterozygous mutations and presenting with system-specific phenotypes, frequently neurologic. FARS2 encodes mitochondrial phenylalanyl transfer ribonucleic acid (RNA) synthetase (mtPheRS), perturbations of which have been reported in 6 cases of an infantile, lethal disease with refractory epilepsy and progressive myoclonus. Here the authors report the case of juvenile onset refractory epilepsy and progressive myoclonus with compound heterozygous FARS2 mutations. The authors describe the clinical course over 6 years of care at their institution and diagnostic studies including electroencephalogram (EEG), brain magnetic resonance imaging (MRI), serum and cerebrospinal fluid analyses, skeletal muscle biopsy histology, and autopsy gross and histologic findings, which include features shared with Alpers-Huttenlocher syndrome, Leigh syndrome, and a previously published case of FARS2 mutation associated infantile onset disease. The authors also present structure-guided analysis of the relevant mutations based on published mitochondrial phenylalanyl transfer RNA synthetase and related protein crystal structures as well as biochemical analysis of the corresponding recombinant mutant proteins. © The Author(s) 2016.

  2. Production frequency effects in perception of phonological variation

    NASA Astrophysics Data System (ADS)

    Connine, Cynthia M.; Ranbom, Larissa J.

    2004-05-01

    Two experiments were conducted that investigated the relationship between phonological variant occurrence frequency (based on a corpus analysis of conversational speech) and auditory word recognition. The variant investigated was an alternation between the presence of [nt] and a nasal flap (e.g., center, cen'er). The corpus analysis showed that 80% of productions are nasal flaps, with wide variability across words (from 0% for ``enter'' to 100% for ``twenty''). In a production goodness rating experiment, listeners rated [nt] productions as better than their nasal flap counterparts. For individual items, a strong positive correlation was found between nasal flap frequency and goodness ratings: words typically produced with nasal flaps were rated as better productions. A lexical decision experiment showed that nasal flap variants were recognized more slowly and less accurately than [nt] versions. The rated quality of the nasal-flapped production was strongly correlated with the results of the lexical decision task: nasal-flapped words considered highly acceptable were recognized more quickly and accurately than words rated as poor nasal flap productions. The results demonstrate a strong relationship between experienced variant frequency and auditory word recognition and suggest that phonological variation is explicitly represented in the mental lexicon.

  3. Monoclonal antibodies with group specificity toward sulfonamides: selection of hapten and antibody selectivity.

    PubMed

    Wang, Zhanhui; Beier, Ross C; Sheng, Yajie; Zhang, Suxia; Jiang, Wenxiao; Wang, Zhaopeng; Wang, Jin; Shen, Jianzhong

    2013-05-01

    Immunoassays based on the current available antibodies for large multi-sulfonamide screening programs have suffered from high selectivity for individual sulfonamides and a wide range of selectivities for different sulfonamides. In this study, five synthesized haptens, HS, BS, CS, SA10, and TS and two sulfonamides, SG and SMX were used as haptens, which may or may not contain a ring structure at the N1 position of the sulfonamides, were selected to evaluate the effectiveness for producing group-specific monoclonal antibodies (MAbs). Mice immunized with three different two-ring haptens were used for hybridoma production, which resulted in three unique MAbs recognizing 10, 13, and 15 sulfonamides showing 50 % inhibition (IC50) at concentrations below 100 ng mL(-1). MAb 4D11 derived from one novel immunizing hapten could recognize 12 sulfonamides with IC50 values ranging from 1.2 to 12.4 ng mL(-1), almost within 1 order of magnitude. These produced MAbs show lower IC50 values in addition to significantly improved group specificity compared with previously generated MAbs. This study clearly indicates that the careful selection of the immunizing hapten has an important effect on the specificity of the generated antibodies.

  4. Public Unconvinced about Environmental Problems.

    ERIC Educational Resources Information Center

    Hayes, Laurie, Ed.

    1991-01-01

    Indicates that, despite all of the attention focused on environmental problems over the past 20 years, the U.S. public has not taken the issue to heart and fails to recognize individual responsibilities necessary to becoming part of the environmental solution process. (Author/JJK)

  5. Inside the Creative Sifter: Recognizing Metacognition in Creativity Development

    ERIC Educational Resources Information Center

    Puryear, Jeb S.

    2016-01-01

    The parallels between cognitive development and creativity are neglected in the literature. Piaget's information transformations are personalized, meaning individual constructions can involve creativity. Vygotsky's work considers the implications and interactions of social influences, conventions, and personal implications for creative…

  6. How People Become Moral--Is Kohlberg Correct and Has He Told Us Enough?

    ERIC Educational Resources Information Center

    Luizzi, Vincent

    1978-01-01

    Recognizing the groundlessness of Kohlberg's dismissal of the Aristotelian view that virtues are acquired individually by practice, that view can possibly work in tandem with Kohlberg's for a complete theory of moral development. (Author/SJL)

  7. Real Supervision?

    ERIC Educational Resources Information Center

    Sull, Theresa M.

    2003-01-01

    Asserts that teachers at child care centers need to use supervision on the playground to promote children's healthy development. Describes characteristics of successful supervision: (1) ensure safety; (2) understand development; (3) permit childish behavior; (4) engage and explain; (5) recognize individuals; (6) vary activities; (7) interest…

  8. The Changing Career Strategies of Managers.

    ERIC Educational Resources Information Center

    Wilson, Tony; Davies, Goronwy

    1999-01-01

    Faced with reduced employment security, managers are redefining careers to include work/personal life balance. Changes in any area can cause revision of career strategies. Depending on how they define careers, managers recognize career development as an individual, not an organizational, responsibility. (SK)

  9. Increasing numbers of bird species result from taxonomic progress, not taxonomic inflation

    PubMed Central

    Sangster, George

    2009-01-01

    The impact and significance of modern taxonomy on other fields in biology have been subjects of much debate. It has been proposed that increasing numbers of vertebrate species are largely owing to ‘taxonomic inflation’. According to this hypothesis, newly recognized species result from reinterpretations of species limits based on phylogenetic species concepts (PSCs) rather than from new discoveries. Here, I examine 747 proposals to change the taxonomic rank of birds in the period 1950–2007. The trend to recognize more species of birds started at least two decades before the introduction of PSCs. Most (84.6%) newly recognized species were supported by new taxonomic data. Proposals to recognize more species resulted from application of all six major taxonomic criteria. Many newly recognized species (63.4%) were not based exclusively on PSC-based criteria (diagnosability, monophyly and exclusive coalescence of gene trees). Therefore, this study finds no empirical support for the idea that the increase in species is primarily epistemological rather than data-driven. This study shows that previous claims about the causes and effects of taxonomic inflation lack empirical support. I argue that a more appropriate term for the increase in species is ‘taxonomic progress’. PMID:19520805

  10. An Evidence Based Approach to Sepsis: Educational Program

    ERIC Educational Resources Information Center

    Perez, Dolores

    2015-01-01

    Evidence-based guidelines for recognizing and treating sepsis have been available for decades, yet healthcare providers do not adhere to the recommendations. Sepsis can progress rapidly if not recognized early. Literature reports reveal that sepsis is the leading cause of death in non-cardiac intensive care units (ICUs), and it is one of the most…

  11. Effect of Educational Debt on Emergency Medicine Residents: A Qualitative Study Using Individual Interviews.

    PubMed

    Young, Timothy P; Brown, Madison M; Reibling, Ellen T; Ghassemzadeh, Sassan; Gordon, Dawn M; Phan, Tammy H; Thomas, Tamara L; Brown, Lance

    2016-10-01

    In 2001, less than 20% of emergency medicine residents had more than $150,000 of educational debt. Our emergency medicine residents anecdotally reported much larger debt loads. Surveys have reported that debt affects career and life choices. Qualitative approaches are well suited to explore how and why such complex phenomena occur. We aim to gain a better understanding of how our emergency medicine residents experience debt. We conducted individual semistructured interviews with emergency medicine residents. We collected self-reported data related to educational debt and asked open-ended questions about debt influence on career choices, personal life, future plans, and financial decisions. We undertook a structured thematic analysis using a qualitative approach based in the grounded theory method. Median educational debt was $212,000. Six themes emerged from our analysis: (1) debt influenced career and life decisions by altering priorities; (2) residents experienced debt as a persistent source of background stress and felt powerless to change it; (3) residents made use of various techniques to negotiate debt in order to focus on day-to-day work; (4) personal debt philosophy, based on individual values and obtained from family, shaped how debt affected each individual; (5) debt had a normative effect and was acculturated in residency; and (6) residents reported a wide range of financial knowledge, but recognized its importance to career success. Our emergency medicine residents' debt experience is complex and involves multiple dimensions. Given our current understanding, simple solutions are unlikely to be effective in adequately addressing this issue. Copyright © 2016 American College of Emergency Physicians. Published by Elsevier Inc. All rights reserved.

  12. Reproducibility of Clathromorphum compactum coralline algal Mg/Ca ratios and comparison to high-resolution sea surface temperature data

    NASA Astrophysics Data System (ADS)

    Hetzinger, S.; Halfar, J.; Kronz, A.; Simon, K.; Adey, W. H.; Steneck, R. S.

    2018-01-01

    The potential of crustose coralline algae as high-resolution archives of past ocean variability in mid- to high-latitudes has only recently been recognized. Few comparisons of coralline algal proxies, such as temperature-dependent algal magnesium to calcium (Mg/Ca) ratios, with in situ-measured surface ocean data exist, even rarer are well replicated records from individual sites. We present Mg/Ca records from nine coralline algal specimens (Clathromorphum compactum) from a single site in the Gulf of Maine, North Atlantic. Sections from algal mounds were analyzed using Laser Ablation-Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) yielding individual Mg/Ca records of up to 30 years in length. We first test intra- and intersample signal replication and show that algal Mg/Ca ratios are reproducible along several transects within individual sample specimens and between different samples from the same study site. In addition, LA-ICP-MS-derived Mg/Ca ratios are compared to electron microprobe (EMP) analyzed data on the longest-lived specimens and were found to be statistically commensurable. Second, we evaluate whether relationships between algal-based SST reconstructions and in situ temperature data can be improved by averaging Mg/Ca records from multiple algal specimens (intersample averages). We found that intersample averages yield stronger relationships to sea surface temperature (SST) data than Mg/Ca records derived from individual samples alone. Thus, Mg/Ca-based paleotemperature reconstructions from coralline algae can benefit from using multiple samples per site, and can expand temperature proxy precision from seasonal to monthly.

  13. Usefulness of multiple chalk-based food colorings for inducing better gene silencing by feeding RNA interference in planarians.

    PubMed

    Hattori, Miki; Miyamoto, Mai; Hosoda, Kazutaka; Umesono, Yoshihiko

    2018-01-01

    Planarians have become widely recognized as one of the major animal models for regeneration studies in invertebrates. To induce RNA interference (RNAi) by feeding in planarians, the widely accepted protocol is one in which animals undergo two or three feedings of food containing double-stranded RNA (dsRNA) plus visible food coloring (e.g., blood) for confirmation of feeding by individual animals. However, one possible problem is that incorporated food coloring is often retained within the gut for several days, which makes it difficult to confirm the success of each round of dsRNA feeding based on the difference of the color density within the gut before and after feeding. As a consequence, the difference of appetite levels among individuals undergoing dsRNA feeding leads to phenotypic variability among them due to insufficient knockdown. In our attempts to overcome this problem, we have developed a novel method for achieving robust confirmation of the success of dsRNA feeding in individuals fed multiple times by means of including a combination of three different colored chalks (pink, yellow and blue) as food coloring. Notably, we found that this method is superior to the conventional method for positively marking individuals that actively consumed the dsRNA-containing food during four times of once-daily feeding. Using these selected animals, we obtained stable and sufficiently strong RNAi-induced phenotypes. We termed this improved multi-colored chalk-spiked method of feeding RNAi "Candi" and propose its benefits for gene function analysis in planarians. © 2017 Japanese Society of Developmental Biologists.

  14. Facades structure detection by geometric moment

    NASA Astrophysics Data System (ADS)

    Jiang, Diqiong; Chen, Hui; Song, Rui; Meng, Lei

    2017-06-01

    This paper proposes a novel method for extracting facades structure from real-world pictures by using local geometric moment. Compared with existing methods, the proposed method has advantages of easy-to-implement, low computational cost, and robustness to noises, such as uneven illumination, shadow, and shade from other objects. Besides, our method is faster and has a lower space complexity, making it feasible for mobile devices and the situation where real-time data processing is required. Specifically, a facades structure modal is first proposed to support the use of our special noise reduction method, which is based on a self-adapt local threshold with Gaussian weighted average for image binarization processing and the feature of the facades structure. Next, we divide the picture of the building into many individual areas, each of which represents a door or a window in the picture. Subsequently we calculate the geometric moment and centroid for each individual area, for identifying those collinear ones based on the feature vectors, each of which is thereafter replaced with a line. Finally, we comprehensively analyze all the geometric moment and centroid to find out the facades structure of the building. We compare our result with other methods and especially report the result from the pictures taken in bad environmental conditions. Our system is designed for two application, i.e, the reconstruction of facades based on higher resolution ground-based on imagery, and the positional system based on recognize the urban building.

  15. Performance of residents and anesthesiologists in a simulation-based skill assessment.

    PubMed

    Murray, David J; Boulet, John R; Avidan, Michael; Kras, Joseph F; Henrichs, Bernadette; Woodhouse, Julie; Evers, Alex S

    2007-11-01

    Anesthesiologists and anesthesia residents are expected to acquire and maintain skills to manage a wide range of acute intraoperative anesthetic events. The purpose of this study was to determine whether an inventory of simulated intraoperative scenarios provided a reliable and valid measure of anesthesia residents' and anesthesiologists' skill. Twelve simulated acute intraoperative scenarios were designed to assess the performance of 64 residents and 35 anesthesiologists. The participants were divided into four groups based on their training and experience. There were 31 new CA-1, 12 advanced CA-1, and 22 CA-2/CA-3 residents as well as a group of 35 experienced anesthesiologists who participated in the assessment. Each participant managed a set of simulated events. The advanced CA-1 residents, CA-2/CA-3 residents, and 35 anesthesiologists managed 8 of 12 intraoperative simulation exercises. The 31 CA-1 residents each managed 3 intraoperative scenarios. The new CA-1 residents received lower scores on the simulated intraoperative events than the other groups of participants. The advanced CA-1 residents, CA-2/CA-3 residents, and anesthesiologists performed similarly on the overall assessment. There was a wide range of scores obtained by individuals in each group. A number of the exercises were difficult for the majority of participants to recognize and treat, but most events effectively discriminated among participants who achieved higher and lower overall scores. This simulation-based assessment provided a valid method to distinguish the skills of more experienced anesthesia residents and anesthesiologists from residents in early training. The overall score provided a reliable measure of a participant's ability to recognize and manage simulated acute intraoperative events. Additional studies are needed to determine whether these simulation-based assessments are valid measures of clinical performance.

  16. Vortex pattern of corneal deposits in granular corneal dystrophy associated with the p. (ArgR555WTrp) mutation in TGFBI

    PubMed Central

    Kattan, Jaffer M.; Serna-Ojeda, Juan Carlos; Sharma, Anushree; Kim, Eung K.; Ramirez-Miranda, Arturo; Cruz-Aguilar, Marisa; Cervantes, Aleck E.; Frausto, Ricardo F.; Zenteno, Juan Carlos; Graue-Hernandez, Enrique O.; Aldave, Anthony J.

    2016-01-01

    Purpose To describe two unrelated families with multiple members demonstrating a less commonly recognized vortex pattern of corneal deposits confirmed to be granular corneal dystrophy type 1(GCD1) following identification of the p.(Arg555Trp) mutation in the transforming growth factor β-induced gene (TGFBI). Methods A slit lamp examination was performed on individuals from two families, one of Mexican descent and a second of Italian descent. Following DNA extraction from affected individuals and their unaffected relatives, TGFBI screening was performed. Results Eight of 20 individuals in the Mexican family and 20 of 55 in the Italian family demonstrated corneal stromal opacities. Seven of the eight affected individuals in the Mexican family and four of the 20 affected individuals in the Italian family demonstrated a phenotype characterized by a “sea fan” or vortex pattern of superficial stromal corneal deposits originating from the inferior aspect of the cornea. Screening of TGFBI in both families revealed a heterozygous missense mutation (p.(Arg555Trp)) in exon 12, confirming the diagnosis of GCD1. Conclusion Our findings demonstrate that GCD1 may present with a vortex pattern of anterior stromal deposits. Although this pattern of dystrophic deposits is not recognized by clinicians as a typical phenotype of GCD1, it is consistent with the production of the majority of the TGFBI protein by the corneal epithelium. PMID:28060069

  17. Privacy and Biobanking in China: A Case of Policy in Transition.

    PubMed

    Chen, Haidan; Chan, Benny; Joly, Yann

    2015-01-01

    Disease-based biobanks have operated in hospitals and research institutes in China for decades, and China has recently embarked on a plan to establish further biobank networks with the aim of promoting data sharing among the existing biobanks. Although the Chinese Constitution has only recently begun to recognize individual privacy as a distinct and independent constitutional right, biobanking in China has been loosely regulated under a patchwork of sometimes overlapping laws (such as the Interim Measures for the Administration of Human Genetic Resources) and regulatory instruments, as well as and the policies of individual biobanks and networks of biobanks (such as the Shanghai Biobank Network Guidelines). A Draft Ordinance on Human Genetics Resources is currently being developed that will deal in more detail than previous laws with issues such as management measures, legal liability, and punishment for violations. International data sharing will be tightly regulated under this new law, and individual biobanks' policies such as the Shanghai Guidelines may choose to regulate such sharing even more. In contrast with national regulatory instruments, the Shanghai Guidelines also contain detailed de-identification policies, and explicitly endorse broad consent. © 2015 American Society of Law, Medicine & Ethics, Inc.

  18. Species, gender, and identity: cracking petrels' sociochemical code.

    PubMed

    Mardon, Jérôme; Saunders, Sandra M; Anderson, Marti J; Couchoux, Charline; Bonadonna, Francesco

    2010-05-01

    Avian chemosignaling remains relatively unexplored, but its potential importance in birds' social behaviors is becoming recognized. Procellariiform seabirds provide particularly appropriate models for investigating these topics as they possess a well-developed olfactory system and unequalled associated capabilities. We present here results from a detailed chemical examination of the uropygial secretions (the main source of avian exogenous chemicals) from 2 petrel species, Antarctic prions and blue petrels. Using gas chromatography-mass spectrometry techniques and recently developed multivariate tools, we demonstrate that the secretions contain critical socioecological information such as species, gender, and individual identity. Importantly, these chemosignals correlate with some of the birds' olfactory behaviors demonstrated in the field. The molecules found to be associated with social information were essentially large unsaturated compounds, suggesting that these may be precursors of, or correlates to the actual airborne signals. Although the species-specific chemosignal may be involved in interspecific competition at the breeding grounds, the role of the sexually specific chemosignal remains unclear. The existence of individually specific signals (i.e., chemical signatures) in these birds has important implications for processes such as individual recognition and genetically based mate choice already suspected for this group. Our results open promising avenues of research for the study of avian chemical communication.

  19. Of monkeys and men: immunomic profiling of sera from humans and non-human primates resistant to schistosomiasis reveals novel potential vaccine candidates.

    PubMed

    Pearson, Mark S; Becker, Luke; Driguez, Patrick; Young, Neil D; Gaze, Soraya; Mendes, Tiago; Li, Xiao-Hong; Doolan, Denise L; Midzi, Nicholas; Mduluza, Takafira; McManus, Donald P; Wilson, R Alan; Bethony, Jeffrey M; Nausch, Norman; Mutapi, Francisca; Felgner, Philip L; Loukas, Alex

    2015-01-01

    Schistosoma haematobium affects more than 100 million people throughout Africa and is the causative agent of urogenital schistosomiasis. The parasite is strongly associated with urothelial cancer in infected individuals and as such is designated a group I carcinogen by the International Agency for Research on Cancer. Using a protein microarray containing schistosome proteins, we sought to identify antigens that were the targets of protective IgG1 immune responses in S. haematobium-exposed individuals that acquire drug-induced resistance (DIR) to schistosomiasis after praziquantel treatment. Numerous antigens with known vaccine potential were identified, including calpain (Smp80), tetraspanins, glutathione-S-transferases, and glucose transporters (SGTP1), as well as previously uncharacterized proteins. Reactive IgG1 responses were not elevated in exposed individuals who did not acquire DIR. To complement our human subjects study, we screened for antigen targets of rhesus macaques rendered resistant to S. japonicum by experimental infection followed by self-cure, and discovered a number of new and known vaccine targets, including major targets recognized by our human subjects. This study has further validated the immunomics-based approach to schistosomiasis vaccine antigen discovery and identified numerous novel potential vaccine antigens.

  20. Clinical Application of Standardized Cognitive Assessment Using fMRI. I. Matrix Reasoning

    PubMed Central

    Allen, Mark D.; Fong, Alina K.

    2008-01-01

    Functional MRI is increasingly recognized for its potential as a powerful new tool in clinical neuropsychology. This is likely due to the fact that, with some degree of innovation, it is possible to convert practically any familiar cognitive test into one that can be performed in the MRI scanning environment. However, like any assessment approach, meaningful interpretation of fMRI data for the purpose of patient evaluation crucially requires normative data derived from a sample of unimpaired persons, against which individual patients may be compared. Currently, no such normative data are available for any fMRI-based cognitive testing protocol. In this paper, we report the first of a series of fMRI-compatible cognitive assessment protocols, a matrix reasoning test (f-MRT), for which normative samples of functional activation have been collected from unimpaired control subjects and structured in a manner that makes individual patient evaluation possible in terms of familiar z-score distributions. Practical application of the f-MRT is demonstrated via a contrastive case-study of two individuals with cognitive impairment in which fMRI data identifies subtleties in patient deficits otherwise missed by conventional measures of performance. PMID:19641250

  1. Positioning of Weight Bias: Moving towards Social Justice

    PubMed Central

    Alberga, Angela S.; Kassan, Anusha; Sesma-Vazquez, Monica

    2016-01-01

    Weight bias is a form of stigma with detrimental effects on the health and wellness of individuals with large bodies. Researchers from various disciplines have recognized weight bias as an important topic for public health and for professional practice. To date, researchers from various areas have approached weight bias from independent perspectives and from differing theoretical orientations. In this paper, we examined the similarities and differences between three perspectives (i.e., weight-centric, non-weight-centric (health-centric), and health at every size) used to understand weight bias and approach weight bias research with regard to (a) language about people with large bodies, (b) theoretical position, (c) identified consequences of weight bias, and (d) identified influences on weight-based social inequity. We suggest that, despite differences, each perspective acknowledges the negative influences that position weight as being within individual control and the negative consequences of weight bias. We call for recognition and discussion of weight bias as a social justice issue in order to change the discourse and professional practices extended towards individuals with large bodies. We advocate for an emphasis on social justice as a uniting framework for interdisciplinary research on weight bias. PMID:27747099

  2. [Social support network and health of elderly individuals with chronic pneumopathies].

    PubMed

    Mesquita, Rafael Barreto de; Morano, Maria Tereza Aguiar Pessoa; Landim, Fátima Luna Pinheiro; Collares, Patrícia Moreira Costa; Pinto, Juliana Maria de Sousa

    2012-05-01

    This study sought to analyze characteristics of the social support network of the elderly with chronic pneumopathies, establishing links with health maintenance/rehabilitation. The assumptions of Social Network Analysis (SNA) methodology were used, addressing the social support concept. A questionnaire and semi-structured interviews, both applied to 16 elderly people attended by a public hospital in Fortaleza-CE, were used for data collection. Quantitative data were processed using the UCINET 6.123, NetDraw 2.38 and Microsoft Excel software programs. In the qualitative analysis, the body of material was subjected to interpretations based on relevant and current theoretical references. Each informant brought an average of 10.37 individuals into the network. Among the 3 types of social support, there was a predominance of informational support given by health professionals. The importance of reciprocity in providing/receiving social support was also noted, as well as the participation of health professionals and the family functioning as social support. The conclusion reached was that the network of the elderly with pneumopathies is not cohesive, being restricted to the personal network of each individual, and that even so, the informants recognize and are satisfied with the social support it provides.

  3. Word recognition in Alzheimer's disease: Effects of semantic degeneration.

    PubMed

    Cuetos, Fernando; Arce, Noemí; Martínez, Carmen; Ellis, Andrew W

    2017-03-01

    Impairments of word recognition in Alzheimer's disease (AD) have been less widely investigated than impairments affecting word retrieval and production. In particular, we know little about what makes individual words easier or harder for patients with AD to recognize. We used a lexical selection task in which participants were shown sets of four items, each set consisting of one word and three non-words. The task was simply to point to the word on each trial. Forty patients with mild-to-moderate AD were significantly impaired on this task relative to matched controls who made very few errors. The number of patients with AD able to recognize each word correctly was predicted by the frequency, age of acquisition, and imageability of the words, but not by their length or number of orthographic neighbours. Patient Mini-Mental State Examination and phonological fluency scores also predicted the number of words recognized. We propose that progressive degradation of central semantic representations in AD differentially affects the ability to recognize low-imageability, low-frequency, late-acquired words, with the same factors affecting word recognition as affecting word retrieval. © 2015 The British Psychological Society.

  4. Physician professionalism and accountability: the role of collaborative improvement networks.

    PubMed

    Miles, Paul V; Conway, Patrick H; Pawlson, L Gregory

    2013-06-01

    The medical profession is facing an imperative to deliver more patient-centered care, improve quality, and reduce unnecessary costs and waste. With significant unexplained variation in resource use and outcomes, even physicians and health care organizations with "the best" reputations cannot assume they always deliver the best care possible. Going forward, physicians will need to demonstrate professionalism and accountability in a different way: to their peers, to society in general, and to individual patients. The new accountability includes quality and clinical outcomes but also resource utilization, appropriateness and patient-centeredness of recommended care, and the responsibility to help improve systems of care. The pediatric collaborative improvement network model represents an important framework for helping transform health care. For individual physicians, participation in a multisite network offers the opportunity to demonstrate accountability by measuring and improving care as part of an approach that addresses the problems of small sample size, attribution, and unnecessary variation in care by pooling patients from individual practices and requiring standardization of care to participate. For patients and families, the model helps ensure that they are likely to receive the current best evidence-based recommendation. Finally, this model aligns with payers' goals of purchasing value-based care, rewarding quality and improvement, and reducing unnecessary variation around current best evidenced-based, effective, and efficient care. In addition, within the profession, the American Board of Pediatrics recognizes participation in a multisite quality improvement network as one of the most rigorous and meaningful approaches for a diplomate to meet practice performance maintenance of certification requirements.

  5. Preliminary competencies for comparative effectiveness research.

    PubMed

    Segal, Jodi B; Kapoor, Wishwa; Carey, Timothy; Mitchell, Pamela H; Murray, Michael D; Saag, Kenneth G; Schumock, Glen; Jonas, Daniel; Steinman, Michael; Filart, Rosemarie; Weinberger, Morris; Selker, Harry

    2012-12-01

    The Clinical and Translational Science Award (CTSA) Workgroup for Comparative Effectiveness Research (CER) Education, Training, and Workforce Development identified a need to delineate the competencies that practitioners and users of CER for patient-centered outcomes research, should acquire. With input from CTSA representatives and collaborators, we began by describing the workforce. We recognize the workforce that conducts CER and the end users who use CER to improve the health of individuals and communities. We generated a preliminary set of competencies and solicited feedback from the CER representatives at each member site of the CTSA consortium. We distinguished applied competencies (i.e., skills needed by individuals who conduct CER) from foundational competencies that are needed by the entire CER workforce, including end users of CER. Key competency categories of relevance to both practitioners and users of CER were: (1) asking relevant research questions; (2) recognizing or designing ideal CER studies; (3) executing or using CER studies; (4) using appropriate statistical analyses for CER; and (5) communicating and disseminating CER study results to improve health. Although CER is particularly broad concept, we anticipate that these preliminary, relatively generic competencies will be used in tailoring curricula to individual learners from a variety of programmatic perspectives. © 2012 Wiley Periodicals, Inc.

  6. Interaction of glycophorin A with lectins as measured by surface plasmon resonance (SPR).

    PubMed

    Krotkiewska, Bozena; Pasek, Marta; Krotkiewski, Hubert

    2002-01-01

    Glycophorin A (GPA), the major sialoglycoprotein of the human erythrocyte membrane, was isolated from erythrocytes of healthy individuals of blood groups A, B and O using phenol-water extraction of erythrocyte membranes. Interaction of individual GPA samples with three lectins (Psathyrella velutina lectin, PVL; Triticum vulgaris lectin, WGA and Sambucus nigra I agglutinin SNA-I) was analyzed using a BIAcore biosensor equipped with a surface plasmon resonance (SPR) detector. The experiments showed no substantial differences in the interaction between native and desialylated GPA samples originating from erythrocytes of either blood group and each of the lectins. Desialylated samples reacted weaker than the native ones with all three lectins. PVL reacted about 50-fold more strongly than WGA which, similar to PVL, recognizes GlcNAc and Neu5Ac residues. SNA-I lectin, recognizing alpha2-6 linked Neu5Ac residues, showed relatively weak reaction with native and only residual reaction with desialylated GPA samples. The data obtained show that SPR is a valuable method to determine interaction of glycoproteins with lectins, which potentially can be used to detect differences in the carbohydrate moiety of individual glycoprotein samples.

  7. Social learning of predators in the dark: understanding the role of visual, chemical and mechanical information.

    PubMed

    Manassa, R P; McCormick, M I; Chivers, D P; Ferrari, M C O

    2013-08-22

    The ability of prey to observe and learn to recognize potential predators from the behaviour of nearby individuals can dramatically increase survival and, not surprisingly, is widespread across animal taxa. A range of sensory modalities are available for this learning, with visual and chemical cues being well-established modes of transmission in aquatic systems. The use of other sensory cues in mediating social learning in fishes, including mechano-sensory cues, remains unexplored. Here, we examine the role of different sensory cues in social learning of predator recognition, using juvenile damselfish (Amphiprion percula). Specifically, we show that a predator-naive observer can socially learn to recognize a novel predator when paired with a predator-experienced conspecific in total darkness. Furthermore, this study demonstrates that when threatened, individuals release chemical cues (known as disturbance cues) into the water. These cues induce an anti-predator response in nearby individuals; however, they do not facilitate learnt recognition of the predator. As such, another sensory modality, probably mechano-sensory in origin, is responsible for information transfer in the dark. This study highlights the diversity of sensory cues used by coral reef fishes in a social learning context.

  8. New Nursing Faculty and Incivility: Applying Mindfulness-Based Strategies.

    PubMed

    Green, Cheryl

    Workplace incivility remains a problem within the nursing profession. As nurse leaders, we must recognize and not ignore the complexity of cultures that have adapted incivility into the work environment. Nursing education is a discipline that requires collaborative team work, independent drive, and commitment. New nursing faculty experiencing incivility can use mindfulness-based meditation approaches to cope with uncivil behaviors experienced within the workplace. Nurse educators applying the concepts of mindfulness can learn how to provide themselves self-care by reducing stress, as enhanced daily awareness of peace and calm are incorporated into their lifestyle. Mindfulness provides a realization that control can only be given to other persons when an individual allows or accepts another's negative behaviors. Awareness of the value and importance of oneself can assist the nurse educator experiencing incivility to maintain his or her emotional, physical, and spiritual health despite the volatility of the work environment.

  9. Inequity aversion and the evolution of cooperation

    NASA Astrophysics Data System (ADS)

    Ahmed, Asrar; Karlapalem, Kamalakar

    2014-02-01

    Evolution of cooperation is a widely studied problem in biology, social science, economics, and artificial intelligence. Most of the existing approaches that explain cooperation rely on some notion of direct or indirect reciprocity. These reciprocity based models assume agents recognize their partner and know their previous interactions, which requires advanced cognitive abilities. In this paper we are interested in developing a model that produces cooperation without requiring any explicit memory of previous game plays. Our model is based on the notion of inequity aversion, a concept introduced within behavioral economics, whereby individuals care about payoff equality in outcomes. Here we explore the effect of using income inequality to guide partner selection and interaction. We study our model by considering both the well-mixed and the spatially structured population and present the conditions under which cooperation becomes dominant. Our results support the hypothesis that inequity aversion promotes cooperative relationship among nonkin.

  10. Inequity aversion and the evolution of cooperation.

    PubMed

    Ahmed, Asrar; Karlapalem, Kamalakar

    2014-02-01

    Evolution of cooperation is a widely studied problem in biology, social science, economics, and artificial intelligence. Most of the existing approaches that explain cooperation rely on some notion of direct or indirect reciprocity. These reciprocity based models assume agents recognize their partner and know their previous interactions, which requires advanced cognitive abilities. In this paper we are interested in developing a model that produces cooperation without requiring any explicit memory of previous game plays. Our model is based on the notion of inequity aversion, a concept introduced within behavioral economics, whereby individuals care about payoff equality in outcomes. Here we explore the effect of using income inequality to guide partner selection and interaction. We study our model by considering both the well-mixed and the spatially structured population and present the conditions under which cooperation becomes dominant. Our results support the hypothesis that inequity aversion promotes cooperative relationship among nonkin.

  11. New stem-sauropodomorph (Dinosauria, Saurischia) from the Triassic of Brazil

    NASA Astrophysics Data System (ADS)

    Cabreira, Sergio F.; Schultz, Cesar L.; Bittencourt, Jonathas S.; Soares, Marina B.; Fortier, Daniel C.; Silva, Lúcio R.; Langer, Max C.

    2011-12-01

    Post-Triassic theropod, sauropodomorph, and ornithischian dinosaurs are readily recognized based on the set of traits that typically characterize each of these groups. On the contrary, most of the early members of those lineages lack such specializations, but share a range of generalized traits also seen in more basal dinosauromorphs. Here, we report on a new Late Triassic dinosaur from the Santa Maria Formation of Rio Grande do Sul, southern Brazil. The specimen comprises the disarticulated partial skeleton of a single individual, including most of the skull bones. Based on four phylogenetic analyses, the new dinosaur fits consistently on the sauropodomorph stem, but lacks several typical features of sauropodomorphs, showing dinosaur plesiomorphies together with some neotheropod traits. This is not an exception among basal dinosaurs, the early radiation of which is characterized by a mosaic pattern of character acquisition, resulting in the uncertain phylogenetic placement of various early members of the group.

  12. Improving Foster Parent Engagement: Using Qualitative Methods to Guide Tailoring of Evidence-based Engagement Strategies

    PubMed Central

    Conover, Kate L.; Cox, Julia Revillion

    2014-01-01

    Objective This qualitative study examined applicability and need for tailoring of an evidence-based engagement intervention, combined with Trauma-focused Cognitive Behavioral Therapy, for foster parents. Method Qualitative methods were used, including individual interviews with participating foster parents (N = 7), review of interview findings with an independent group of foster parents (N = 5), and review of the combined foster parent findings by child welfare caseworkers (N = 5), an important stakeholder group. Results The engagement intervention, with its primary focus on perceptual barriers (e.g., past experiences with mental health), was relevant for the foster care population. However, the study identified areas for tailoring to better recognize and address the unique needs and situation of foster parents as substitute caregivers. Conclusions Perceptually-focused engagement interventions may have broad applicability to a range of populations, including foster parents, with the potential for improving caregiver participation in children’s mental health services. PMID:24611600

  13. Tandem carrying, a new foraging strategy in ants: description, function, and adaptive significance relative to other described foraging strategies

    NASA Astrophysics Data System (ADS)

    Guénard, Benoit; Silverman, Jules

    2011-08-01

    An important aspect of social insect biology lies in the expression of collective foraging strategies developed to exploit food. In ants, four main types of foraging strategies are typically recognized based on the intensity of recruitment and the importance of chemical communication. Here, we describe a new type of foraging strategy, "tandem carrying", which is also one of the most simple recruitment strategies, observed in the Ponerinae species Pachycondyla chinensis. Within this strategy, workers are directly carried individually and then released on the food resource by a successful scout. We demonstrate that this recruitment is context dependent and based on the type of food discovered and can be quickly adjusted as food quality changes. We did not detect trail marking by tandem-carrying workers. We conclude by discussing the importance of tandem carrying in an evolutionary context relative to other modes of recruitment in foraging and nest emigration.

  14. An evaluation-guided approach for effective data visualization on tablets

    NASA Astrophysics Data System (ADS)

    Games, Peter S.; Joshi, Alark

    2015-01-01

    There is a rising trend of data analysis and visualization tasks being performed on a tablet device. Apps with interactive data visualization capabilities are available for a wide variety of domains. We investigate whether users grasp how to effectively interpret and interact with visualizations. We conducted a detailed user evaluation to study the abilities of individuals with respect to analyzing data on a tablet through an interactive visualization app. Based upon the results of the user evaluation, we find that most subjects performed well at understanding and interacting with simple visualizations, specifically tables and line charts. A majority of the subjects struggled with identifying interactive widgets, recognizing interactive widgets with overloaded functionality, and understanding visualizations which do not display data for sorted attributes. Based on our study, we identify guidelines for designers and developers of mobile data visualization apps that include recommendations for effective data representation and interaction.

  15. Using Cooperative Small Groups in Introductory Accounting Classes: A Practical Approach.

    ERIC Educational Resources Information Center

    Miglietti, Cynthia

    2002-01-01

    Effective use of cooperative learning groups requires the following: attention to group formation, orientation that sets clear expectations and guidelines, activities to develop teamwork skills, peer evaluation, and other assessments that recognize and measure individual effort on group projects. (SK)

  16. Intelligent transportation systems field operational test cross-cutting study incident management : detection, verification, and traffic management

    DOT National Transportation Integrated Search

    2000-01-01

    Although the effects of climatic factors on pavement performance have long been recognized as important, those effects remain largely unquantified because individual pavement research projects to date generally have been restricted to limited geograp...

  17. 45 CFR 261.52 - Is there a way to waive the State's penalty for failing to achieve either of the participation...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... domestic violence waivers (i.e., it provides evidence that it achieved the applicable work rates when individuals receiving federally recognized good cause domestic violence waivers of work requirements, in...

  18. From "DSM" to "DM-ID"

    ERIC Educational Resources Information Center

    Fletcher, Robert J.; Barnhill, Jarrett; McCarthy, Jane; Strydom, André

    2016-01-01

    Recognizing the diagnostic challenges that clinicians face when attempting to arrive at an accurate psychiatric diagnosis for individuals with intellectual and developmental disabilities (IDD) co-occurring with mental illness (MI), in 2007 the National Association for the Dually Diagnosed (NADD), in association with the American Psychiatric…

  19. Exercise and Aging.

    ERIC Educational Resources Information Center

    Clarke, H. Harrison, Ed.

    1977-01-01

    In this presentation on exercise and aging, the following explanations are made: the nature of physical fitness, physical fitness values, the importance of recognizing individual differences, physiological changes occurring with age through the adult years, physical fitness studies pertaining to middle-aged persons, the trainability of older…

  20. 77 FR 10725 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-23

    ... Management and Budget (OMB) for clearance the following proposal for collection of information under the... (USPTO). Title: National Medal of Technology and Innovation Nomination Application. Form Number(s): None... Innovation Nomination Application to recognize through nomination an individual's or company's extraordinary...

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