Sample records for recorded fertility problems

  1. Self-reported difficulty in conceiving as a measure of infertility.

    PubMed

    Dick, M-L B; Bain, C J; Purdie, D M; Siskind, V; Molloy, D; Green, A C

    2003-12-01

    This study aimed to explore the meaning and potential use of women's self-reported difficulties in conceiving as a measure of infertility in epidemiological studies, and to compare women's stated reasons for infertility with information in their medical records. Data were available from a population-based case-control study of ovarian cancer involving 1638 women. The sensitivity and specificity of women's self-reported infertility were calculated against their estimated fertility status based on detailed reproductive histories. Self-reported reasons for infertility were compared with diagnoses documented in women's medical records. The sensitivity of women's self-reported difficulty in conceiving was 66 and 69% respectively when compared with calendar-derived and self-reported times taken trying to conceive; its specificity was 95%. Forty-one (23%) of the 179 women for whom medical records were available had their self-reported fertility problem confirmed. Self-reported infertility causes could be compared with diagnoses in medical records for only 22 of these women. Self-reported difficulty conceiving is a useful measure of infertility for quantifying the burden of fertility problems experienced in the community. Validation of reasons for infertility is unlikely to be feasible through examination of medical records. Improved education of the public regarding the availability and success rates of infertility treatments is proposed.

  2. Veterinary dairy herd fertility service provision in seasonal and non-seasonal dairy industries - a comparison

    PubMed Central

    2010-01-01

    The decline in dairy herd fertility internationally has highlighted the limited impact of traditional veterinary approaches to bovine fertility management. Three questionnaire surveys were conducted at buiatrics conferences attended by veterinary practitioners on veterinary dairy herd fertility services (HFS) in countries with a seasonal (Ireland, 47 respondents) and non-seasonal breeding model (The Netherlands, 44 respondents and Portugal, 31 respondents). Of the 122 respondents, 73 (60%) provided a HFS and 49 (40%) did not. The majority (76%) of all practitioners who responded stated that bovine fertility had declined in their practice clients' herds with inadequate cow management, inadequate nutrition and increased milk yield as the most important putative causes. The type of clients who adopted a herd fertility service were deemed more educated than average (70% of respondents), and/or had fertility problems (58%) and/or large herds (53%). The main components of this service were routine postpartum examinations (95% of respondents), fertility records analysis (75%) and ultrasound pregnancy examinations (69%). The number of planned visits per annum varied between an average of four in Ireland, where breeding is seasonal, and 23 in Portugal, where breeding is year-round. The benefits to both the practitioner and their clients from running a HFS were cited as better fertility, financial rewards and job satisfaction. For practitioners who did not run a HFS the main reasons given were no client demand (55%) and lack of fertility records (33%). Better economic evidence to convince clients of the cost-benefit of such a service was seen as a major constraint to adoption of this service by 67% of practitioners. PMID:21851745

  3. Herd monitoring to optimise fertility in the dairy cow: making the most of herd records, metabolic profiling and ultrasonography (research into practice).

    PubMed

    Smith, R F; Oultram, J; Dobson, H

    2014-05-01

    Fertility performance is intrinsically linked to the quality of the animal environment, overall management and nutrition. This review describes the use of dairy herd records, metabolic profiles and ultrasonographic findings at veterinary fertility examinations to monitor and manage dairy herd fertility. After calving, a cow has to overcome a series of physiological hurdles before establishing a pregnancy. The selection of timely key performance indicators (KPIs) that monitor specific events in the postpartum and service periods is vital to correctly identify problems and their potential causes that hopefully can be rectified. Cumulative sum charts are the timeliest monitors of efficiency of detection of oestrus, insemination outcome and relationship between postpartum events and fertility, with the point of inflection indicating when a change took place. Other KPIs use data from specific cohorts, adding an inherent delay to when change is indicated. Metabolic profiles and milk constituent data allow monitoring of nutritional adequacy and developments to offer new possibilities of on-farm systems for regular measurements of milk constituents (including progesterone) and energy status. Examination of the reproductive tract can be used to indicate individual and herd fertility status but the currently available detail is under used. Recent advances in ultrasonography can improve the diagnosis of reproductive tract pathophysiology still further but the clinical use of these methods in veterinary practice needs further evaluation. Development of new KPIs to exploit research findings are needed to ensure this knowledge is used to improve on-farm performance.

  4. Divorce or end of cohabitation among Danish women evaluated for fertility problems.

    PubMed

    Kjaer, Trille; Albieri, Vanna; Jensen, Allan; Kjaer, Susanne K; Johansen, Christoffer; Dalton, Susanne O

    2014-03-01

    Couples with fertility problems may experience marital or sexual distress which could potentially result in dissolved relationships. We investigated the likelihood of ending a relationship among women who did not have a child after a fertility evaluation. Longitudinal cohort study. Danish women ever referred for primary or secondary fertility problems to a public Danish hospital or private fertility clinic between 1990 and 2006. A total of 47,515 women. The data were linked to Danish administrative population-based registries containing demographic and socioeconomic information. Discrete-time survival models were used with person-period data. Each woman was followed from the year of her initial fertility evaluation through to 2007. Effects of parity after a fertility evaluation on the likelihood of ending a marital or cohabitation relationship. After up to 12 years of follow up, nearly 27% of the women were no longer living with the person with whom they had lived at the time of the fertility evaluation. Women who did not have a child after the evaluation had significantly higher odds ratios for ending a relationship up to 12 years after the evaluation (with odds ratios up to 3.13, 95% CI 2.88-3.41) than women who had a child, regardless of their parity before the evaluation. Parity after a fertility evaluation may be an important component in the longitudinal relationships of couples with fertility problems. Studies with detailed information on marital quality and relational well-being of couples with fertility problems are needed. © 2014 Nordic Federation of Societies of Obstetrics and Gynecology.

  5. If you did not document it, it did not happen: rates of documentation of discussion of infertility risk in adolescent and young adult oncology patients' medical records.

    PubMed

    Quinn, Gwendolyn P; Block, Rebecca G; Clayman, Marla L; Kelvin, Joanne; Arvey, Sarah R; Lee, Ji-Hyun; Reinecke, Joyce; Sehovic, Ivana; Jacobsen, Paul B; Reed, Damon; Gonzalez, Luis; Vadaparampil, Susan T; Laronga, Christine; Lee, M Catherine; Pow-Sang, Julio; Eggly, Susan; Franklin, Anna; Shah, Bijal; Fulp, William J; Hayes-Lattin, Brandon

    2015-03-01

    The adolescent and young adult (AYA) population is underserved because of unique late-effect issues, particularly future fertility. This study sought to establish rates of documentation of discussion of risk of infertility, fertility preservation (FP) options, and referrals to fertility specialists in AYA patients' medical records at four cancer centers. All centers reviewed randomized records within the top four AYA disease sites (breast, leukemia/lymphoma, sarcoma, and testicular). Eligible records included those of patients: diagnosed in 2011, with no prior receipt of gonadotoxic therapy; age 18 to 45 years; with no multiple primary cancers; and for whom record was not second opinion. Quality Oncology Practice Initiative methods were used to evaluate documentation of discussion of risk of infertility, discussion of FP options, and referral to a fertility specialist. Of 231 records, 26% documented infertility risk discussion, 24% documented FP option discussion, and 13% documented referral to a fertility specialist. Records were less likely to contain evidence of infertility risk and FP option discussions for female patients (P = .030 and .004, respectively) and those with breast cancer (P = .021 and < .001, respectively). Records for Hispanic/Latino patients were less likely to contain evidence of infertility risk discussion (P = .037). Records were less likely to document infertility risk discussion, FP option discussion, and fertility specialist referral for patients age ≥ 40 years (P < .001, < .001, and .002, respectively) and those who already had children (all P < .001). The overall rate of documentation of discussion of FP is low, and results show disparities among specific groups. Although greater numbers of discussions may be occurring, there is a need to create interventions to improve documentation. Copyright © 2014 by American Society of Clinical Oncology.

  6. Factors influencing the documentation of fertility-related discussions for adolescents and young adults with cancer.

    PubMed

    Skaczkowski, G; White, V; Thompson, K; Bibby, H; Coory, M; Pinkerton, R; Nicholls, W; Orme, L M; Conyers, R; Phillips, M B; Osborn, M; Harrup, R; Anazodo, A

    2018-06-01

    A cancer diagnosis and treatment may have significant implications for a young patient's future fertility. Documentation of fertility-related discussions and actions is crucial to providing the best follow-up care, which may occur for many years post-treatment. This study examined the rate of medical record documentation of fertility-related discussions and fertility preservation (FP) procedures for adolescents and young adults (AYAs) with cancer in Australia. A retrospective review of medical records for 941 patients in all six Australian states. Patients were identified through population-based cancer registries (four states) and hospital admission lists (two states). Trained data collectors extracted information from medical records using a comprehensive data collection survey. Records were reviewed for AYA patients (aged 15-24 years at diagnosis), diagnosed with acute myeloid leukaemia, acute lymphoblastic leukaemia, central nervous system (CNS) tumours, soft tissue sarcomas (STS), primary bone cancer or Ewing's family tumours between 2007 and 2012. 47.2% of patients had a documented fertility discussion and 35.9% had a documented FP procedure. Fertility-related documentation was less likely for female patients, those with a CNS or STS diagnosis and those receiving high-risk treatments. In multivariable models, adult hospitals with an AYA focus were more likely to document fertility discussions (odds ratio[OR] = 1.60; 95%CI = 1.08-2.37) and FP procedures (OR = 1.74; 95%CI = 1.17-2.57) than adult hospitals with no AYA services. These data provide the first national, population-based estimates of fertility documentation for AYA cancer patients in Australia. Documentation of fertility-related discussions was poor, with higher rates observed in hospitals with greater experience of treating AYA patients. Copyright © 2018 Elsevier Ltd. All rights reserved.

  7. Claims for fertility interventions: a systematic assessment of statements on UK fertility centre websites

    PubMed Central

    Spencer, E A; Mahtani, K R; Goldacre, B; Heneghan, C

    2016-01-01

    Objectives Fertility services in the UK are offered by over 200 Human Fertilisation and Embryology Authority (HFEA)-registered NHS and private clinics. While in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI) form part of the National Institute for Health and Care Excellence (NICE) guidance, many further interventions are offered. We aimed to record claims of benefit for interventions offered by fertility centres via information on the centres' websites and record what evidence was cited for these claims. Methods We obtained from HFEA a list of all UK centres providing fertility treatments and examined their websites. We listed fertility interventions offered in addition to standard IVF and ICSI and recorded statements about interventions that claimed or implied improvements in fertility in healthy women. We recorded which claims were quantified, and the evidence cited in support of the claims. Two reviewers extracted data from websites. We accessed websites from 21 December 2015 to 31 March 2016. Results We found 233 websites for HFEA-registered fertility treatment centres, of which 152 (65%) were excluded as duplicates or satellite centres, 2 were andrology clinics and 5 were unavailable or under construction websites. In total, 74 fertility centre websites, incorporating 1401 web pages, were examined for claims. We found 276 claims of benefit relating to 41 different fertility interventions made by 60 of the 74 centres (median 3 per website; range 0 to 10). Quantification was given for 79 (29%) of the claims. 16 published references were cited 21 times on 13 of the 74 websites. Conclusions Many fertility centres in the UK offer a range of treatments in addition to standard IVF procedures, and for many of these interventions claims of benefit are made. In most cases, the claims are not quantified and evidence is not cited to support the claims. There is a need for more information on interventions to be made available by fertility centres, to support well-informed treatment decisions. PMID:27890866

  8. Current Internet use and preferences of IVF and ICSI patients.

    PubMed

    Haagen, E C; Tuil, W; Hendriks, J; de Bruijn, R P J; Braat, D D M; Kremer, J A M

    2003-10-01

    Nowadays, the Internet has a tremendous impact on modern society, including healthcare practice. The study aim was to characterize current Internet use by IVF and ICSI patients and to identify their preferences regarding Internet applications in fertility care. A total of 163 couples with fertility problems awaiting an IVF or ICSI procedure in the University Medical Centre Nijmegen, The Netherlands, was asked to complete a written questionnaire on Internet use in general, and also for fertility-related problems, preferences regarding Internet applications in fertility care and demographic characteristics. The response rate was 82%. In total, 81% of infertile couples used the Internet. Multivariate logistic regression analysis showed ethnic background and annual family income to be significant predictors of Internet use. Some 66% of Internet users and 54% of the total study population used the Internet for fertility-related problems. The female partners were the main Internet users with regard to fertility-related issues. In terms of preferences of the study participants, the majority favoured personal medical information online. Most infertile couples used the Internet with respect to fertility-related problems and were interested in implementation of Internet applications in fertility care. Healthcare providers should actively participate in the development and implementation of Internet applications in fertility care.

  9. Fertilizers mobilization in alluvial aquifer: laboratory experiments

    NASA Astrophysics Data System (ADS)

    Mastrocicco, M.; Colombani, N.; Palpacelli, S.

    2009-02-01

    In alluvial plains, intensive farming with conspicuous use of agrochemicals, can cause land pollution and groundwater contamination. In central Po River plain, paleo-channels are important links between arable lands and the underlaying aquifer, since the latter is often confined by clay sediments that act as a barrier against contaminants migration. Therefore, paleo-channels are recharge zones of particular interest that have to be protected from pollution as they are commonly used for water supply. This paper focuses on fertilizer mobilization next to a sand pit excavated in a paleo-channel near Ferrara (Italy). The problem is approached via batch test leaking and columns elution of alluvial sediments. Results from batch experiments showed fast increase in all major cations and anions, suggesting equilibrium control of dissolution reactions, limited availability of solid phases and geochemical homogeneity of samples. In column experiments, early elution and tailing of all ions breakthrough was recorded due to preferential flow paths. For sediments investigated in this study, dispersion, dilution and chemical reactions can reduce fertilizers at concentration below drinking standards in a reasonable time frame, provided fertilizer loading is halted or, at least, reduced. Thus, the definition of a corridor along paleo-channels is recommended to preserve groundwater quality.

  10. Factor structure and psychometric properties of the Fertility Problem Inventory–Short Form

    PubMed Central

    Zurlo, Maria Clelia; Cattaneo Della Volta, Maria Franscesca; Vallone, Federica

    2017-01-01

    The study analyses factor structure and psychometric properties of the Italian version of the Fertility Problem Inventory–Short Form. A sample of 206 infertile couples completed the Italian version of Fertility Problem Inventory (46 items) with demographics, State Anxiety Scale of State-Trait Anxiety Inventory (Form Y), Edinburgh Depression Scale and Dyadic Adjustment Scale, used to assess convergent and discriminant validity. Confirmatory factor analysis was unsatisfactory (comparative fit index = 0.87; Tucker-Lewis Index = 0.83; root mean square error of approximation = 0.17), and Cronbach’s α (0.95) revealed a redundancy of items. Exploratory factor analysis was carried out deleting cross-loading items, and Mokken scale analysis was applied to verify the items homogeneity within the reduced subscales of the questionnaire. The Fertility Problem Inventory–Short Form consists of 27 items, tapping four meaningful and reliable factors. Convergent and discriminant validity were confirmed. Findings indicated that the Fertility Problem Inventory–Short Form is a valid and reliable measure to assess infertility-related stress dimensions. PMID:29379625

  11. Claims for fertility interventions: a systematic assessment of statements on UK fertility centre websites.

    PubMed

    Spencer, E A; Mahtani, K R; Goldacre, B; Heneghan, C

    2016-11-27

    Fertility services in the UK are offered by over 200 Human Fertilisation and Embryology Authority (HFEA)-registered NHS and private clinics. While in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI) form part of the National Institute for Health and Care Excellence (NICE) guidance, many further interventions are offered. We aimed to record claims of benefit for interventions offered by fertility centres via information on the centres' websites and record what evidence was cited for these claims. We obtained from HFEA a list of all UK centres providing fertility treatments and examined their websites. We listed fertility interventions offered in addition to standard IVF and ICSI and recorded statements about interventions that claimed or implied improvements in fertility in healthy women. We recorded which claims were quantified, and the evidence cited in support of the claims. Two reviewers extracted data from websites. We accessed websites from 21 December 2015 to 31 March 2016. We found 233 websites for HFEA-registered fertility treatment centres, of which 152 (65%) were excluded as duplicates or satellite centres, 2 were andrology clinics and 5 were unavailable or under construction websites. In total, 74 fertility centre websites, incorporating 1401 web pages, were examined for claims. We found 276 claims of benefit relating to 41 different fertility interventions made by 60 of the 74 centres (median 3 per website; range 0 to 10). Quantification was given for 79 (29%) of the claims. 16 published references were cited 21 times on 13 of the 74 websites. Many fertility centres in the UK offer a range of treatments in addition to standard IVF procedures, and for many of these interventions claims of benefit are made. In most cases, the claims are not quantified and evidence is not cited to support the claims. There is a need for more information on interventions to be made available by fertility centres, to support well-informed treatment decisions. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  12. Effect of cow manure and empty fruit bunches application treated with different fertilizers on growth and yield of chili (Capsicum annum)

    NASA Astrophysics Data System (ADS)

    Ghazali, Mohd Rashdan; Mutalib, Sahilah Abd.; Abdullah, Aminah

    2016-11-01

    Study on the comparison of cow manure (CM) and empty fruit bunches (EFB) compost application as planting medium was conducted using four different treatments of fertilizer (without fertilizer, chemical fertilizer, organic fertilizer, and both fertilizer) on growth and yield of chili (Capsicum annum). The experiment started on August until December 2014 which consisted of eight treatments and were laid in a completely randomized block design (CRBD) with three replications. Variety chili that was used was Cilibangi 3. The seed was planted inside the tray for one week and transferred into the polybag containing growth media consisted of soil, compost (CM or EFB compost) and sand with ratio 3:2:1. Treatments without fertilizer were acted as a control. Throughout the study, plant growth performance and yield were recorded. The highest height of the plants for CM compost was 100.8 cm using chemical fertilizer and have significant different between the groups. For EFB compost was 92.7 cm using also chemical fertilizer but no significant different between the groups. The highest fruits weight per plant for CM compost was 485.67 g treated with both fertilizers and for EFB compost was 420.17 g treated with chemical fertilizer. Analysis of variance (ANOVA) table stated that fruits weight per plant has significant different for both planting medium with the fertilizer treatment. For the highest total fruits per plant, CM compost recorded about average 55 fruits per plant using both fertilizers and EFB compost recorded around 45 fruit per plant using chemical fertilizer. There was significantly different for total fruits per plant for both planting medium with the fertilizer treatment according to the ANOVA table. For CM, the ripening time was around 102-112 days and for EFB compost was around 96-110 days. Thus, application of CM compost treated with both chemical and organic fertilizers demonstrated better growth and fruit yield. While EFB compost was better growth and fruit yield when treated with chemical fertilizer.

  13. Mental disorders in childhood and young adulthood among children born to women with fertility problems.

    PubMed

    Svahn, M F; Hargreave, M; Nielsen, T S S; Plessen, K J; Jensen, S M; Kjaer, S K; Jensen, A

    2015-09-01

    Is the risk of hospital admission or outpatient contact for mental disorders increased in children born to women with fertility problems compared with children born to women without fertility problems? We found an increased risk of hospital admission or outpatient contact for mental disorders in children born to women with fertility problems. Few studies have investigated the risk of mental disorders in children born after fertility treatment and although some studies have pointed to an increased risk, others found no association. The inconsistent results may be due to methodological constraints in many previous studies, including small sample size and short follow-up, resulting in imprecise risk estimates and lack of information on risk patterns of mental disorders in adulthood. This nationwide retrospective register-based cohort study included all 2 412 721 children born in Denmark between 1969 and 2006. All children were followed from date of birth until date of hospital contact for a mental disorder, date of emigration, date of death or 31 December 2009, whichever occurred first. Information concerning maternal fertility status for all children in the cohort was obtained by linkage to the Danish Infertility Cohort, which contains data on nearly all women with fertility problems in Denmark since 1963. A total of 124 269 (5%) children were born to women with fertility problems and 2 288 452 (95%) to women without fertility problems. To identify children hospitalized for a mental disorder, the cohort was linked to the Danish Psychiatric Central Research Registry. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for the association between maternal fertility status and the risk of hospital admission or outpatient contact for various groups of mental disorders, including any mental disorder and all 11 main discharge diagnostic groups, classified according to the International Classification of Diseases, version 10. During a mean follow-up period of 21 years (range, 0-40 years), 168 686 (7%) children were admitted to hospital or had an outpatient contact for a mental disorder. Children born to women with fertility problems had a significantly higher risk of any mental disorder (HR 1.23; 95% CI 1.20-1.26) and for most of the 11 main discharge groups, including schizophrenia (HR 1.16; 95% CI 1.07-1.27), mood (affective) disorders (HR 1.21; 95% CI 1.15-1.28) and disorders of psychological development (HR 1.15; 95% CI 1.09-1.21) as well as the subgroup of attention-deficit/hyperactivity disorders (HR 1.36; 95% CI 1.29-1.45) compared with children born to women without fertility problems. The risk estimates did not change markedly when analyses were performed separately for mental disorders diagnosed during childhood (0-19 years) and in young adulthood (20-40 years). The true risk of mental disorders may be somewhat underestimated, as only severe disorders requiring hospital admission or outpatient contact were considered as events. Furthermore, we could not determine whether the increased risks observed were due to factors related to the underlying infertility or to fertility treatment procedures. This is the first report on mental disorders in adulthood among children born to women with fertility problems. Furthermore, we have assessed the risk of several severe mental disorders not previously studied (e.g. neurotic, stress-related and somatoform disorders and disorders of adult personality and behaviour). These important findings should be investigated further in large epidemiological studies designed to differentiate between factors related to fertility treatment and to the underlying infertility. The study was supported by internal funding from the Unit of Virus, Lifestyle and Genes at the Danish Cancer Society Research Center. All authors report no conflicts of interest. © The Author 2015. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  14. Studies on hepatic lipidosis and coinciding health and fertility problems of high-producing dairy cows using the "Utrecht fatty liver model of dairy cows". A review.

    PubMed

    Geelen, M J H; Wensing, T

    2006-09-01

    Fatty liver or hepatic lipidosis is a major metabolic disorder of high-producing dairy cows that occurs rather frequently in early lactation and is associated with decreased health, production and fertility. A background section of the review explores reasons why high-producing dairy cows are prone to develop fatty liver post partum. Hepatic lipidosis and coinciding health and fertility problems seriously endanger profitability and longevity of the dairy cow. Results from a great number of earlier epidemiological and clinical studies made it clear that a different approach was needed for elucidation of pathogenesis and etiology of this complex of health problems. There was a need for an adequate animal model in which hepatic lipidosis and production, health and fertility problems could be provoked under controlled conditions. It was hypothesized that overconditioning ante partum and feed restriction post partum might induce lipolysis in adipose tissue and triacylglycerol accumulation in the liver following calving. This consideration formed the basis for the experiments, which resulted in the "Utrecht fatty liver model of dairy cows". In this model, post partum triacylglycerol-lipidosis as well as the whole complex of health and fertility problems are induced under well-controlled conditions. The experimental protocol based on this hypothesis produced in all cases (10 feeding trials with over 150 dairy cattle) the intended result, i.e. all experimental cows developed post partum higher hepatic triacylglycerol concentrations than did control cows. The model was evaluated in biochemical, clinical pathology, immunological, clinical and fertility terms. It turned out that in this model, post partum triacylglycerol-lipidosis as well as the whole complex of health and fertility problems were induced under well-controlled conditions.

  15. Evaluating the influence of plant growth-promoting rhizobacteria as a bio-fertilizer under different fertility sources

    USDA-ARS?s Scientific Manuscript database

    Chemical fertilizers are being extensively used to satisfy the increasing demand for food. However, utilization of chemical fertilizers can be costly and over application for ensuring crop productivity may lead to environmental problems. As a result, interest in using bio-fertilizers to improve soil...

  16. Impact of mineral fertility and bedrock erosion on single-mineral detrital studies: insights from trace-element and Nd-isotope systematics of detrital apatite from the Po River catchment

    NASA Astrophysics Data System (ADS)

    Malusa', Marco Giovanni; Wang, Jiangang; Garzanti, Eduardo; Villa, Igor M.; Wittman, Hella

    2017-04-01

    The detrital record provides an archive of mountain erosion that preserves key information for paleotectonic and paleoclimatic reconstructions. Detrital studies are often based on single-mineral analyses (e.g., geo/thermochronologic analyses on apatite and zircon). Their geologic interpretation can be challenging, because the impact of each eroding source on the detrital record is controlled by a range of factors including the rate of erosion and the fertility of chosen minerals in eroded bedrock. Here, we combine (i) a state-of-the art dataset of trace element and Nd isotope fingerprints of detrital apatite, (ii) a comprehensive dataset of apatite-fertility measurements (Malusà et al. 2016), (iii) fission-track data, and (iv) cosmogenic-derived erosion rates from the Po River catchment (Wittmann et al. 2016), to test the impact of mineral fertility and bedrock erosion on the single-mineral detrital signal preserved in the final sediment sink. Our results show that the information provided by accessory minerals, when complemented with accurate mineral fertility measurements, are fully consistent with information provided by the analysis of more abundant framework minerals. We found that trace element and Nd isotope analyses provide a reliable tool to disentangle the complex single-mineral record of orogenic erosion, and demonstrate that such a record is largely determined by high-fertility source rocks exposed within the drainage. Detrital thermochronology studies based on the lag-time approach should thus preferably include independent provenance discriminations and a full mineral fertility characterization of the potential source areas, in order to ensure a correct identification of the sediment sources and of the exogenic and endogenic processes monitored in the stratigraphic archive. Malusà M.G., Resentini A., Garzanti E., 2016. Hydraulic sorting and mineral fertility bias in detrital geochronology. Gondwana Res., 31, 1-19 Wittmann H., Malusà M.G., Resentini A., Garzanti E., Niedermann S., 2016. The cosmogenic record of mountain erosion transmitted across a foreland basin: Source-to-sink analysis of in situ 10Be, 26Al and 21Ne in sediment of the Po river catchment. Earth Planet. Sci. Lett. 452, 258-271

  17. Multitrait modeling of first vs. later parities for US yield, somatic cell score, and fertility traits

    USDA-ARS?s Scientific Manuscript database

    Genetic merits in first vs. later parity with correlations <1 were compared to official repeatability models using 88 million lactation records of 34 million cows for yield traits and fewer records for somatic cell score (SCS) and 2 cow fertility traits. Estimated genetic correlations of first with ...

  18. Validity of self-reported fertility-threatening cancer treatments in female young adult cancer survivors.

    PubMed

    Roberts, Samantha C; Knight, Amber; Whitcomb, Brian W; Gorman, Jessica R; Dietz, Andrew C; Irene Su, H

    2017-08-01

    Detailed cancer treatment information is important to fertility and pregnancy care of female young adult cancer survivors. Accuracy of self-report of treatments that impact fertility and pregnancy is unknown. This study assessed agreement between self-report and medical records on receipt of fertility-threatening treatments. A national cohort study of female young adult cancer survivors reported cancer treatments via Web-based questionnaires. Primary cancer treatment records were abstracted. Self-reported exposure to fertility-threatening therapies (alkylating chemotherapy, stem cell transplant, pelvic radiation, hysterectomy, and/or oophorectomy) was compared to medical records. Logistic regression models estimated odds ratios (OR) for characteristics associated with inaccurate self-report of fertility-threatening therapies. The study included 101 survivors (mean age 28.2, SD 6.3). Lymphoma (33%), breast cancer (26%), and gynecologic cancers (10%) were the most common cancers. Accuracy of self-report was 68% for alkylating chemotherapy and 92-97% for radiation, surgery, and transplant. Significant proportions of survivors who were treated with transplant (8/13, 62%), alkylating chemotherapy (18/43, 42%), pelvic radiation (4/13, 31%), or hysterectomy and/or oophorectomy (3/13, 23%) did not report undergoing these therapies. In adjusted analysis, age ≤ 25 at diagnosis (OR 3.4, 95% CI 1.3-8.7) and recurrence (OR 6.0, 95% CI 1.5-24.4) were related to inaccurate self-report. Female young adult cancer survivors have limited recall of fertility-threatening cancer treatment exposures. Reproductive health providers and researchers who need this information may require primary medical records or treatment summaries. Additional patient education regarding treatment-related reproductive risks is needed to facilitate patient engagement in survivorship. Obtaining a cancer treatment summary will help survivors communicate their prior treatment exposures to reproductive healthcare providers.

  19. [Body, rights and comprehensive health: Analysis of the parliamentary debates on the Gender Identity and Assisted Fertilization Laws (Argentina, 2011-2013)].

    PubMed

    Farji Neer, Anahí

    2015-09-01

    In this paper we present an analysis of the parliamentary debates of the Gender Identity Law (No. 26743) and the Assisted Fertilization Law (No. 26862) carried out in the Argentine National Congress between 2011 and 2013. Using a qualitative content analysis technique, the stenographic records of the debates were analyzed to explore the following questions: How was the public problem to which each law responds characterized? How was the mission of each law conceptualized? To what extent did those definitions call into question ideas of health and illness, in including in the public health system coverage for certain medical treatments of body optimization or modification? In the process of sanctioning both laws, the concepts of health and disease were put into dispute as moral categories. In this context, an expanded concept of comprehensive health arose, in which desires regarding reproduction and the body were included.

  20. Managing Chemotherapy Side Effects: Sexual and Fertility Changes in Men

    MedlinePlus

    ... Chemotherapy Side Effects Sexual and Fertility Changes in Men “I talked with my doctor before treatment. I ... other health issues are also important. Questions from men about sexual problems: What sexual problems might I ...

  1. [Hygienic problems in the manufacture and usage of fertilizers].

    PubMed

    Tulakan, A V; Mekhant'eva, L E

    2008-01-01

    The paper presents review data on the hygienic problems in the turnover of fertilizers. Agrochemicals are shown to be an additional source of the emission of a number of pollutants into the environment (ambient air, soil, water sources, and foodstuffs). There is evidence that it is important to update environmental hygiene and occupational medicine and to elaborate preventive and health-improving measures when fertilizers and other agrochemicals are manufactured and applied.

  2. Physiological responses to fertilization recorded in tree rings: isotopic lessons from a long-term fertilization trial - 2008

    EPA Science Inventory

    Nitrogen fertilizer applications are common land-use management tools, but details on physiological responses to these applications are often lacking, particularly for long-term responses over decades of forest management. We used tree-ring growth patterns and stable isotopes to...

  3. Physiological responses to fertilization recorded in tree rings: Isotopic lessons from a long-term fertilization trial

    EPA Science Inventory

    Nitrogen fertilizer applications are common land use management tools, but details on physiological responses to these applications are often lacking, particularly for long-term responses over decades of forest management. We used tree ring growth patterns and stable isotopes to ...

  4. The fertility quality of life (FertiQoL) tool: development and general psychometric properties†

    PubMed Central

    Boivin, Jacky; Takefman, Janet; Braverman, Andrea

    2011-01-01

    BACKGROUND To develop the first international instrument to measure fertility quality of life (FertiQoL) in men and women experiencing fertility problems, to evaluate the preliminary psychometric properties of this new tool and to translate FertiQoL into multiple languages. METHOD We conducted a survey, both online and in fertility clinics in USA, Australia/New Zealand, Canada and UK. A total of 1414 people with fertility problems participated. The main outcome measure was the FertiQoL tool. RESULTS FertiQoL consists of 36 items that assess core (24 items) and treatment-related quality of life (QoL) (10 items) and overall life and physical health (2 items). Cronbach reliability statistics for the Core and Treatment FertiQoL (and subscales) were satisfactory and in the range of 0.72 and 0.92. Sensitivity analyses showed that FertiQoL detected expected relations between QoL and gender, parity and support-seeking. FertiQoL was translated into 20 languages by the same translation team with each translation verified by local bilingual fertility experts. CONCLUSIONS FertiQoL is a reliable measure of the impact of fertility problems and its treatment on QoL. Future research should establish its use in cross-cultural research and clinical work. PMID:21665875

  5. Thin and fat cows, and the nonlinear genetic relationship between body condition score and fertility.

    PubMed

    Tiezzi, F; Maltecca, C; Cecchinato, A; Penasa, M; Bittante, G

    2013-10-01

    Thin and fat cows are often credited for low fertility, but body condition score (BCS) has been traditionally treated as a linear trait when genetic correlations with reproductive performance have been estimated. The aims of this study were to assess genetic parameters for fertility, production, and body condition traits in the Brown Swiss population reared in the Alps (Bolzano-Bozen Province, Italy), and to investigate the possible nonlinearity among BCS and other traits by analyzing fat and thin cows. Records of BCS measured on a 5-point scale were preadjusted for year-season and days in milk at scoring, and were considered positive (1) for fat cows if they exceeded the value of 1 residual standard deviation or null (0) otherwise, whereas positive values for thin cows were imputed to records below -1 residual standard deviation. Fertility indicators measured on first- and second-parity cows were interval from parturition to first service, interval from first service to conception, interval from parturition to conception, number of inseminations to conception, conception at first service, and nonreturn rate at 56 d after first service. Production traits were peak milk yield, lactation milk yield, and lactation length. Data were from 1,413 herds and included 16,324 records of BCS, fertility, and production for first-parity, and 10,086 fertility records for second-parity cows. Animals calved from 2002 to 2007 and were progeny of 420 artificial insemination bulls. Genetic parameters for the aforementioned traits were obtained under univariate and bivariate threshold and censored linear sire models implemented in a Bayesian framework. Posterior means of heritabilities for BCS, fat cows, and thin cows were 0.141, 0.122, and 0.115, respectively. Genetic correlations of body condition traits with contemporary production were moderate to high and were between -0.556 and 0.623. Body condition score was moderately related to fertility in first (-0.280 to 0.497) and second (-0.392 to 0.248) lactation. The fat cow trait was scarcely related to fertility, particularly in first-parity cows (-0.203 to 0.281). Finally, the genetic relationships between thin cows and fertility were higher than those between BCS and fertility, both in first (-0.456 to 0.431) and second (-0.335 to 0.524) lactation. Body condition score can be considered a predictor of fertility, and it could be included in evaluation either as linear measure or as thin cow. In the second case, the genetic relationship with fertility was stronger, exacerbating the poorest body condition and considering the possible nonlinearity between fertility and energy reserves of the cow. Copyright © 2013 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  6. Risk for borderline ovarian tumours after exposure to fertility drugs: results of a population-based cohort study.

    PubMed

    Bjørnholt, Sarah Marie; Kjaer, Susanne Krüger; Nielsen, Thor Schütt Svane; Jensen, Allan

    2015-01-01

    Do fertility drugs increase the risk for borderline ovarian tumours, overall and according to histological subtype? The use of any fertility drug did not increase the overall risk for borderline ovarian tumours, but an increased risk for serous borderline ovarian tumours was observed after the use of progesterone. Many epidemiological studies have addressed the connection between fertility drugs use and risk for ovarian cancer; most have found no strong association. Fewer studies have assessed the association between use of fertility drugs and risk for borderline ovarian tumours, and the results are inconsistent. A retrospective case-cohort study was designed with data from a cohort of 96 545 Danish women with fertility problems referred to all Danish fertility clinics in the period 1963-2006. All women were followed for first occurrence of a borderline ovarian tumour from the initial date of infertility evaluation until a date of migration, date of death or 31 December 2006, whichever occurred first. The median length of follow-up was 11.3 years. Included in the analyses were 142 women with borderline ovarian tumours (cases) and 1328 randomly selected sub-cohort members identified in the cohort during the follow-up through 2006. Cases were identified by linkage to the Danish Cancer Register and the Danish Register of Pathology by use of personal identification numbers. To obtain information on use of fertility drugs, hospital files and medical records of infertility-associated visits to all Danish fertility clinics were collected and supplemented with information from the Danish IVF register. We used case-cohort techniques to calculate rate ratios (RRs) and corresponding 95% confidence intervals (CIs) for borderline ovarian tumours, overall and according to histological subtype, associated with the use of any fertility drug or five specific groups of fertility drugs: clomiphene citrate, gonadotrophins (human menopausal gonadotrophins and follicle-stimulating hormone), gonadotrophin-releasing hormone analogues, human chorionic gonadotrophins and progesterone. Analyses within the cohort showed that the overall risk for borderline ovarian tumours was not associated with the use of any fertility drug (RR 1.00; 95% CI 0.67-1.51) or of gonadotrophins (RR 1.32; 95% CI 0.81-2.14), clomiphene citrate (RR 0.96; 95% CI 0.64-1.44), human chorionic gonadotrophins (RR 0.91; 95% CI 0.61-1.36) or gonadotrophin-releasing hormone analogues (RR 1.10; 95% CI 0.66-1.81). Furthermore, no associations were observed between the risk for borderline ovarian tumours and these groups of fertility drugs according to the number of cycles of use, length of follow-up or parity. In contrast, use of progesterone increased the risk for borderline ovarian tumours, particularly serous tumours, for which statistically significantly increased risks were observed with any use of progesterone (RR 1.82; 95% CI 1.03-3.24), among women treated with ≥4 cycles of progesterone (RR 2.63; 95% CI 1.04-6.64) and for all women followed up for ≥4 years after their first treatment with progesterone. Although we tried to minimize the effects of the underlying infertility, the severity of infertility might have affected our risk estimates, as women with more severe fertility problems may receive more treatment. The results from the subgroup analyses, e.g. the findings of an elevated risk for borderline ovarian tumours associated with increased time since first use of progesterone and with increased number of treatment cycles, should be interpreted with caution as these analyses are based on a limited number of women with borderline ovarian tumours. Although this study, which is the largest to date, provides reassuring evidence that there is no strong link between the use of fertility drugs and risk for borderline ovarian tumours, the novel observation of an increased risk for serous tumours after use of progesterone should be investigated in large epidemiological studies. The results of the present study provide valuable knowledge for clinicians and other health care personnel involved in the diagnosis and treatment of fertility problems. No conflict of interest was reported. S.M.B. was supported by a research scholarship from the Danish Cancer Society. © The Author 2014. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  7. Quantifying cradle-to-farm gate life-cycle impacts associated with fertilizer used for corn, soybean, and stover production

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Powers, Susan E.

    2005-05-01

    Fertilizer use can cause environmental problems, particularly eutrophication of water bodies from excess nitrogen or phosphorus. Increased fertilizer runoff is a concern for harvesting corn stover for ethanol production.

  8. Time Costs of Fertility Care: The Hidden Hardship of Building a Family

    PubMed Central

    Wu, Alex K; Elliott, Peter; Katz, Patricia P.; Smith, James F.

    2013-01-01

    Objective To determine the time infertile couples spend seeking and utilizing fertility care. Design Prospective cohort. Setting 8 community and academic infertility practices. Patients 319 couples presenting for a fertility evaluation. Interventions Face-to-face and telephone interviews and questionnaires. Main Outcome Measures Participants recorded diaries of time spent on provider visits, travel, telephone, and miscellaneous activities. Participants also recorded time off of work due to the physical and mental stress related to fertility care. Linear regression was used to assess relationship between fertility characteristics and time spent pursuing care. Results Diaries were completed by 319 subjects. Over an 18 month time period, the average time spent on fertility care was 125 hours, equating to 15.6 days, assuming an 8 hour work day. For couples utilizing cycle-based treatments (CBT), overall time spent pursuing care averaged 142 hours versus 58 hours for couples using other therapies, with the majority of time spent on provider visits (73 hours). After multivariable adjustment for clinical and sociodemographic characteristics, possessing a college degree and intensity of fertility treatment were independently associated with increased time spent pursuing fertility care. Furthermore, couples that spent the most time on care were significantly more likely to experience fertility related stress. Conclusions Over the course of 18 months of observation, couples pursuing fertility treatment dedicated large amounts of time to attaining their family building goals. This burden on couples adds to the already significant financial and emotional burdens of fertility treatment and provides new insight into the difficulties these couples face. PMID:23454007

  9. Fertility and Female Employment: Problems of Causal Direction.

    ERIC Educational Resources Information Center

    Cramer, James C.

    1980-01-01

    Considers multicollinearity in nonrecursive models, misspecification of models, discrepancies between attitudes and behavior, and differences between static and dynamic models as explanations for contradictory information on the causal relationship between fertility and female employment. Finds that initially fertility affects employment but that,…

  10. The impact of cross-border reproductive care or 'fertility tourism' on NHS maternity services.

    PubMed

    McKelvey, A; David, A L; Shenfield, F; Jauniaux, E R

    2009-10-01

    High order multiple pregnancies have substantial morbidity and mortality. Fertility treatment is commonly responsible for their conception and is available globally with variable regulation. We investigated cross-border fertility treatment in these pregnancies in a UK fetal medicine unit, recording mode of conception, country of fertility treatment, reason for non-UK treatment and fetal reduction. Over an 11-year period, 109 women had a high order multiple pregnancy. Ninety-four women (86%) conceived with fertility treatment of whom 24 (26%) had this performed overseas. Cross-border fertility treatment poses an increasing challenge to obstetricians. National data on its occurrence is urgently needed.

  11. Fertility and sexual function in female Hodgkin lymphoma survivors of reproductive age.

    PubMed

    Eeltink, Corien M; Incrocci, Luca; Witte, Birgit I; Meurs, Saskia; Visser, Otto; Huijgens, Peter; Verdonck-de Leeuw, Irma M

    2013-12-01

    To assess the perceived fertility status and to determine the association between perceived fertility status and sexual function, as reported by young female Hodgkin lymphoma survivors. Young female Hodgkin lymphoma survivors are at risk of infertility and impaired sexual function. However, little is known about their awareness of infertility and its association with sexual functioning. A descriptive questionnaire survey. In this cross-sectional study, a survey was completed by female Hodgkin lymphoma survivors (< 40 years). Outcome measures included self-reported fertility status and sexual problems and the internationally validated Female Sexual Function Index. In total, 36 survivors were included (mean age 32 years, SD 4). Eighteen women (50%) thought themselves fertile. Eight survivors (22%) who perceived themselves as being infertile were more often treated with alkylator-based chemotherapy, and 63% reported sexual dysfunction. Ten survivors (28%) were not aware as to whether they were fertile or not; seven of these would like to have children. The reported fertility status was related to age and chemotherapy regimen. Regarding sexuality, 14 (39%) of the female Hodgkin lymphoma survivors reported one or more sexual problem and none reported recovery. Female sexual dysfunction according to the Female Sexual Function Index was reported by 11 (31%) survivors. Almost 30% of Hodgkin lymphoma survivors do not know whether they are fertile or not. Overall sexual dysfunction is common in Hodgkin lymphoma survivors and comparable to the general population. However, a lack of desire was significantly more often reported in female Hodgkin lymphoma survivors. To prevent assumed infertility and unintended childlessness by postponing parenthood in young female survivors, awareness of fertility status is needed. There is also a need to routinely assess sexual function and provide adequate interventions to improve arousal and lubrication problems. © 2013 John Wiley & Sons Ltd.

  12. Improving Rice Modeling Success Rate with Ternary Non-structural Fertilizer Response Model.

    PubMed

    Li, Juan; Zhang, Mingqing; Chen, Fang; Yao, Baoquan

    2018-06-13

    Fertilizer response modelling is an important technical approach to realize metrological fertilization on rice. With the goal of solving the problems of a low success rate of a ternary quadratic polynomial model (TPFM) and to expand the model's applicability, this paper established a ternary non-structural fertilizer response model (TNFM) based on the experimental results from N, P and K fertilized rice fields. Our research results showed that the TNFM significantly improved the modelling success rate by addressing problems arising from setting the bias and multicollinearity in a TPFM. The results from 88 rice field trials in China indicated that the proportion of typical TNFMs that satisfy the general fertilizer response law of plant nutrition was 40.9%, while the analogous proportion of TPFMs was only 26.1%. The recommended fertilization showed a significant positive linear correlation between the two models, and the parameters N 0 , P 0 and K 0 that estimated the value of soil supplying nutrient equivalents can be used as better indicators of yield potential in plots where no N or P or K fertilizer was applied. The theoretical analysis showed that the new model has a higher fitting accuracy and a wider application range.

  13. Tillage, Mulch and N Fertilizer Affect Emissions of CO2 under the Rain Fed Condition

    PubMed Central

    Tanveer, Sikander Khan; Wen, Xiaoxia; Lu, Xing Li; Zhang, Junli; Liao, Yuncheng

    2013-01-01

    A two year (2010–2012) study was conducted to assess the effects of different agronomic management practices on the emissions of CO2 from a field of non-irrigated wheat planted on China's Loess Plateau. Management practices included four tillage methods i.e. T1: (chisel plow tillage), T2: (zero-tillage), T3: (rotary tillage) and T4: (mold board plow tillage), 2 mulch levels i.e., M0 (no corn residue mulch) and M1 (application of corn residue mulch) and 5 levels of N fertilizer (0, 80, 160, 240, 320 kg N/ha). A factorial experiment having a strip split-split arrangement, with tillage methods in the main plots, mulch levels in the sub plots and N-fertilizer levels in the sub-sub plots with three replicates, was used for this study. The CO2 data were recorded three times per week using a portable GXH-3010E1 gas analyzer. The highest CO2 emissions were recorded following rotary tillage, compared to the lowest emissions from the zero tillage planting method. The lowest emissions were recorded at the 160 kg N/ha, fertilizer level. Higher CO2 emissions were recorded during the cropping year 2010–11 relative to the year 2011–12. During cropping year 2010–11, applications of corn residue mulch significantly increased CO2 emissions in comparison to the non-mulched treatments, and during the year 2011–12, equal emissions were recorded for both types of mulch treatments. Higher CO2 emissions were recorded immediately after the tillage operations. Different environmental factors, i.e., rain, air temperatures, soil temperatures and soil moistures, had significant effects on the CO2 emissions. We conclude that conservation tillage practices, i.e., zero tillage, the use of corn residue mulch and optimum N fertilizer use, can reduce CO2 emissions, give better yields and provide environmentally friendly options. PMID:24086256

  14. [Preliminary determination of organic pollutants in agricultural fertilizers].

    PubMed

    Mo, Ce-hui; Li, Yun-hui; Cai, Quan-ying; Zeng, Qiao-yun; Wang, Bo-guang; Li, Hai-qin

    2005-05-01

    Organic pollutants such as polycyclic aromatic hydrocarbons (PAHs) in agricultural fertilizers are new problem deserved more study. Eight kinds of organic pollutants including 43 compounds classified as US EPA priority pollutants in twenty one agricultural fertilizers which were universally used in China were determined by Gas chromatography-mass spectrum (GC-MS). Three kinds of organic pollutants including more than 5 compounds were detected in most fertilizers, composing mainly of phthalic acid esters (PAEs), nitrobenzenes (NBs) and polycyclic aromatic hydrocarbons (PAHs). There were 26 compounds detected in at least one fertilizer, five of them especially PAEs detected in most fertilizer and even in all fertilizers. Benzo(a)pyrene, a strongly carcinogenic compound was detected in two fertilizers. Higher concentrations of compounds were determined in those fertilizers such as multifunction compound fertilizers and coated fertilizers.

  15. Adolescent fertility management: the Sierra Leone experience.

    PubMed

    Lamin, M M; Singleton, A

    1982-01-01

    Because of growing concerns for the problems of adolescent fertility, a training program in Adolescent Fertility Management was conducted in Sierra Leone in 1981. The program was designed to actuate the interdisciplinary energies necessary for exploring the depth of the problem and to develop strategies for possible solutions. 2 program activities were conducted: a Former Participant Conference, which resulted in the development of a draft of a country-wide program; and a 2-week training workshop. In order to create public awareness, the participants presented an original drama, a synopsis of which is provided. Solutions to the problems of adolescent fertility must address not only the availability and use of contraceptives, but also a reorientation of the attitudes of parents on sex education. The practice of expelling pregnant adolescents from educational institutions only serves to compound the problems. A list of the topics covered during the workshops is provided, as are a summary of the conclusions and subsequent recommendations. Participants voted to form a national organization whose main objective is the reduction of teenage pregnancy by at least 12% within a 12 month period through the creation of a national awareness campaign.

  16. Sperm chromatin alterations in fertile and subfertile bulls.

    PubMed

    Souza, Elisson Terêncio; Silva, Cláudio Vieira; Travençolo, Bruno Augusto Nassif; Alves, Benner Geraldo; Beletti, Marcelo Emílio

    2018-06-01

    Alterations in sperm chromatin have been related with subfertility in several mammals. In this study, chromatin alteration types (Base, Basal half, Central axis, Dispersed, and Whole) were assessed by toluidine blue (TB) staining, 6-diamidino-2-fenilindole (DAPI) and anti-protamine 1 antibody (anti-PR1) labeling in sperm samples of fertile and subfertile bulls. Semen samples were obtained from bulls kept in Artificial Insemination Center (fertile bulls) or from bulls subjected to scrotal insulation (subfertile bulls). The percentage of chromatin alterations identified by TB was similar (P > 0.05) in semen samples of fertile and subfertile bulls. In contrast, a greater (P < 0.01) chromatin decondensation and heterogeneity were recorded in semen samples of subfertile bulls. In DAPI and anti-PR1 methods, the subfertile bulls samples had a higher (P < 0.05) percentage of alteration in the base as well as overall chromatin alterations (P < 0.05). Moreover, the chromatin alterations recorded with TB, DAPI, and anti-PR1 were compared in semen samples of fertile and subfertile bulls. In fertile bulls, the overall chromatin alterations were similar (P > 0.05) among the methods In contrast, semen samples of subfertile bulls had a higher (P < 0.05) percentage of overall chromatin alterations when labeled with DAPI. In conclusion, our findings shown that all dye tested had specific sperm stainability and can be feasible to monitor subfertility condition in bulls. Also, different chromatin alteration types in sperm samples of fertile and suberftile bulls were recorded. Copyright © 2018 Society for Biology of Reproduction & the Institute of Animal Reproduction and Food Research of Polish Academy of Sciences in Olsztyn. Published by Elsevier B.V. All rights reserved.

  17. Language Problems in Demographic Field Work in Africa: The Case of the Cameroon Fertility Survey. Scientific Reports, No. 2.

    ERIC Educational Resources Information Center

    Ware, Helen

    This report is the result of a two-month study commissioned by the World Fertility Survey prior to the inclusion of Cameroon in the WFS program, in order to examine the problem of linguistic diversity and the obstacles this problem might pose to a demographic survey of the country. The study was to propose a strategy which would uphold the WFS…

  18. A survey of the attitudes of infertile and parous women towards the availability of assisted reproductive technology.

    PubMed

    Heikkilä, Katri; Länsimies, Esko; Hippeläinen, Maritta; Heinonen, Seppo

    2004-11-01

    The aim of the study was to assess differences in attitudes towards aspects of assisted reproduction technology between infertile and parous women. Case-control study. University-based tertiary care clinic. Three hundred and ninety-two women with fertility problems and 200 parous controls. A questionnaire was sent out to 392 the members of Childless Support Association and 200 parous women who had at least three infants and had given birth at Kuopio University Hospital. The questionnaire consisted of 46 questions: demographic information, fertility history, different aspects of assisted reproduction technology and prioritisation issues. Attitudes towards assisted reproduction technology. The overall response rate was 46%. Infertile women were highly educated (P < 0.01) and had lower parity (mean 0.83 vs 4.76, P < 0.01) than parous women. We recorded four major differences in attitudes between the two groups (OR >2 or <0.5) including provision of infertility treatment to lesbian (46.9% vs 16.7%) and homosexual couples (28.4% vs 11.4%), the opportunity for homosexual couples to use surrogate mothers (30.6% vs 15.2%) and limitations in the number of infertility treatment cycles (28.4% vs 61.4%). For 11 questions, we recorded minor, but statistically significant, differences. In the prioritisation questions, the women set the order according to their own interests, probably because the women were at fertile age and they had or would like to have a child. Maternity services and screening for cancer in women (Papanicolaou's test and mammography) were at the top of the list. These results reflect a split attitude that was influenced by the wish of infertile women to help childless couples and to be able to recruit suitable sperm/oocyte donors. Parous women were motivated by their concern for children's rights.

  19. Does Embryo Culture Medium Influence the Health and Development of Children Born after In Vitro Fertilization?

    PubMed

    Bouillon, Céline; Léandri, Roger; Desch, Laurent; Ernst, Alexandra; Bruno, Céline; Cerf, Charline; Chiron, Alexandra; Souchay, Céline; Burguet, Antoine; Jimenez, Clément; Sagot, Paul; Fauque, Patricia

    2016-01-01

    In animal studies, extensive data revealed the influence of culture medium on embryonic development, foetal growth and the behaviour of offspring. However, this impact has never been investigated in humans. For the first time, we investigated in depth the effects of embryo culture media on health, growth and development of infants conceived by In Vitro Fertilization until the age of 5 years old. This single-centre cohort study was based on an earlier randomized study. During six months, in vitro fertilization attempts (No. 371) were randomized according to two media (Single Step Medium--SSM group) or Global medium (Global group). This randomized study was stopped prematurely as significantly lower pregnancy and implantation rates were observed in the SSM group. Singletons (No. 73) conceived in the randomized study were included (42 for Global and 31 for SSM). The medical data for gestational, neonatal and early childhood periods were extracted from medical records and parental interviews (256 variables recorded). The developmental profiles of the children in eight domains (social, self-help, gross motor, fine motor, expressive language, language comprehension, letter knowledge and number knowledge--270 items) were compared in relation to the culture medium. The delivery rate was significantly lower in the SSM group than in the Global group (p<0.05). The culture medium had no significant effect on birthweight, risk of malformation (minor and major), growth and the frequency of medical concerns. However, the children of the Global group were less likely than those of the SSM group to show developmental problems (p = 0.002), irrespective of the different domains. In conclusion, our findings showed that the embryo culture medium may have an impact on further development.

  20. Global assessment of nitrogen fertilizer: the SCOPE/IGBP nitrogen fertilizer rapid assessment project.

    PubMed

    Mosier, Arvin R; Syers, J Keith; Freney, John R

    2005-12-01

    Nitrogen (N) availability is a key role in food and fiber production. Providing plant-available N through synthetic fertilizer in the 20th and early 21st century has been a major contributor to the increased production required to feed and clothe the growing human population. To continue to meet the global demands and to minimize environmental problems, significant improvements are needed in the efficiency with which fertilizer N is utilized within production systems. There are still major uncertainties regarding the fate of fertilizer N added to agricultural soils and the potential for reducing losses to the environment. Enhancing the technical and economic efficiency of fertilizer N is seen to promote a favorable situation for both agricultural production and the environment, and this has provided much of the impetus for a new N fertilizer project. To address this important issue, a rapid assessment project on N fertilizer (NFRAP) was conducted by SCOPE (the Scientific Committee on Problems of the Environment) during late 2003 and early 2004. This was the first formal project of the International Nitrogen Initiative (INI). As part of this assessment, a successful international workshop was held in Kampala, Uganda on 12 -16 January, 2004. This workshop brought together scientists from around the world to assess the fate of synthetic fertilizer N in the context of overall N inputs to agricultural systems, with a view to enhancing the efficiency of N use and reducing negative impacts on the environment. Regionalization of the assessment highlighted the problems of too little N for crop production to meet the nutrient requirements of sub-Saharan Africa and the oversupply of N in the major rice-growing areas of China. The results of the assessment are presented in a book (SCOPE 65) which is now available to provide a basis for further discussions on N fertilizer.

  1. Global assessment of nitrogen fertilizer: the SCOPE/IGBP nitrogen fertilizer rapid assessment project.

    PubMed

    Mosier, Arvin R; Syers, J Keith; Freney, John R

    2005-09-01

    Nitrogen (N) availability is a key role in food and fiber production. Providing plant-available N through synthetic fertilizer in the 20th and early 21st century has been a major contributor to the increased production required to feed and clothe the growing human population. To continue to meet the global demands and to minimize environmental problems, significant improvements are needed in the efficiency with which fertilizer N is utilized within production systems. There are still major uncertainties regarding the fate of fertilizer N added to agricultural soils and the potential for reducing losses to the environment. Enhancing the technical and economic efficiency of fertilizer N is seen to promote a favorable situation for both agricultural production and the environment, and this has provided much of the impetus for a new N fertilizer project. To address this important issue, a rapid assessment project on N fertilizer (NFRAP) was conducted by SCOPE (the Scientific Committee on Problems of the Environment) during late 2003 and early 2004. This was the first formal project of the International Nitrogen Initiative (INI). As part of this assessment, a successful international workshop was held in Kampala, Uganda on 12 -16 January, 2004. This workshop brought together scientists from around the world to assess the fate of synthetic fertilizer N in the context of overall N inputs to agricultural systems, with a view to enhancing the efficiency of N use and reducing negative impacts on the environment. Regionalization of the assessment highlighted the problems of too little N for crop production to meet the nutrient requirements of sub-Saharan Africa and the oversupply of N in the major rice-growing areas of China. The results of the assessment are presented in a book (SCOPE 65) which is now available to provide a basis for further discussions on N fertilizer.

  2. [Assisted fertilization: meditations on the new legislation].

    PubMed

    Oyarzún, E; Manzur, A

    1997-02-01

    We review philosophical and controversial aspects of assisted fertilization. This exercise is necessary considering the discussion of a bill in the Parliament that intends to regulate these technologies in our Country. We review the definition of life beginning and the cost-benefit problem of adoption as an alternative to assisted fertilization.

  3. Economic and Fertility Differences between Legal and Illegal Migrant Mexican Families: The Potential Effects of Immigration Policy Changes.

    ERIC Educational Resources Information Center

    Falasco, Dee; Heer, David M.

    How the fertility of currently undocumented migrants might be affected by amnesty was examined within the context of Economic Theory of Fertility. Data were collected in 1980-81 from a sample of births recorded in Los Angeles County in which the mother or father was reported to be of Mexican descent. Multiple regression analyses for male and…

  4. Using the product threshold model for estimating separately the effect of temperature on male and female fertility.

    PubMed

    Tusell, L; David, I; Bodin, L; Legarra, A; Rafel, O; López-Bejar, M; Piles, M

    2011-12-01

    Animals under environmental thermal stress conditions have reduced fertility due to impairment of some mechanisms involved in their reproductive performance that are different in males and females. As a consequence, the most sensitive periods of time and the magnitude of effect of temperature on fertility can differ between sexes. The objective of this study was to estimate separately the effect of temperature in different periods around the insemination time on male and on female fertility by using the product threshold model. This model assumes that an observed reproduction outcome is the result of the product of 2 unobserved variables corresponding to the unobserved fertilities of the 2 individuals involved in the mating. A total of 7,625 AI records from rabbits belonging to a line selected for growth rate and indoor daily temperature records were used. The average maximum daily temperature and the proportion of days in which the maximum temperature was greater than 25°C were used as temperature descriptors. These descriptors were calculated for several periods around the day of AI. In the case of males, 4 periods of time covered different stages of the spermatogenesis, the transit through the epididymus of the sperm, and the day of AI. For females, 5 periods of time covered the phases of preovulatory follicular maturation including day of AI and ovulation, fertilization and peri-implantational stage of the embryos, embryonic and early fetal periods of gestation, and finally, late gestation until birth. The effect of the different temperature descriptors was estimated in the corresponding male and female liabilities in a set of threshold product models. The temperature of the day of AI seems to be the most relevant temperature descriptor affecting male fertility because greater temperature records on the day of AI caused a decrease in male fertility (-6% in male fertility rate with respect to thermoneutrality). Departures from the thermal zone in temperature descriptors covering several periods before AI until early gestation had a negative effect on female fertility, with the pre- and peri-implantational period of the embryos being especially sensitive (from -5 to -6% in female fertility rate with respect to thermoneutrality). The latest period of gestation was unaffected by the temperature. Overall, magnitude and persistency of the temperatures reached in the conditions of this study do not seem to be great enough to have a large effect on male and female rabbit fertility.

  5. [Induced abortion: a vulnerable public health problem].

    PubMed

    Requena, M

    1991-03-01

    Induced abortion is an urgent public health problem that can be controlled if it is approached in its true complexity and with a social and humanist perspective. Induced abortion has been discussed in Chile since the last century, but not always openly. Abortion is not just an individual and collective medical problem, it is also an ethical, religious, legal, demographic, political, and psychological problem. Above all it is a problem of human rights. In the past 60 years, more than 50 countries representing 76% of the world population have liberalized their abortion legislation. Around 980 million women have some degrees of access of legal abortion. The magnitude of illegal abortion is difficult to determine because of the desire of women to hide their experiences. Estimates of the incidence of abortion in Chile made some 25 years ago are no longer valid because of the numerous social changes in the intervening years. The number of abortions in Chile in 1987 was estimated using an indirect residual method at 195,441, of which 90%, or 175,897, were induced. By this estimate, 38.8% of pregnancies in Chile end in abortion. Data on hospitalizations for complications of induced abortion show an increase from 13.9/1000 fertile aged women in 1940 to 29.1 in 1965. By 1987, with increased contraceptive usage, the rate declined to 10.5 abortions per 1000 fertile aged women. The cost of hospitalization for abortion complications in 1987, despite the decline, was still estimated at US $4.3 million, a large sum in an era of declining health resources. The problem of induced abortion can be analyzed by placing it in the context of elements affecting the desire to control fertility. 4 complexes of variables are involved: those affecting the supply of contraceptive, the demand for contraceptives, the various costs of fertility control measure, and alternatives to fertility control for satisfying various needs. The analysis is further complicated when efforts are made to understand the dynamics of the process. Awareness of fertility control is a social process that matures slowly. Contraception and abortion have different significance for fertility control, with contraception preventing pregnancy and abortion is a sense curing it. Chile has progressed far in its fertility control awareness. 2/3 of sexually active women use some form of contraception. At the same time, induced abortion is also used. It is estimated that 58% of abortions occur after a contraceptive failure. It appears that recourse to abortion would be minimized if strategies centered on supply of contraceptives were complemented by stronger efforts to develop awareness of fertility control. Delivery of contraceptives should be accompanied by complete information on their effective use. Efforts should be targeted especially at groups at high risk abortion, including adolescents and women hospitalized for complications.

  6. Analysis of Iron in Lawn Fertilizer: A Sampling Study

    ERIC Educational Resources Information Center

    Jeannot, Michael A.

    2006-01-01

    An experiment is described which uses a real-world sample of lawn fertilizer in a simple exercise to illustrate problems associated with the sampling step of a chemical analysis. A mixed-particle fertilizer containing discrete particles of iron oxide (magnetite, Fe[subscript 3]O[subscript 4]) mixed with other particles provides an excellent…

  7. Sexual Problems

    MedlinePlus Videos and Cool Tools

    ... Research SART's FAQs about In Vitro Fertilization REPRODUCTIVE HEALTH TOPICS Topics Index NEWS AND PUBLICATIONS Publications Overview ... Insurance Laws Protect Your Fertility Campaign Find a Health Professional ABOUT ASRM Vision of ASRM ASRM's Mission ...

  8. The ambiguity of patient-centred practices: the case of a Dutch fertility clinic.

    PubMed

    Gerrits, Trudie

    2014-01-01

    When in-vitro fertilization (IVF) was introduced in the 1970s, doctors were criticized for not properly informing prospective users about its possible risks and limited success rates as well as for medicalizing fertility problems. Nowadays, many fertility clinics are seeking to improve their accountability to stakeholders through patient-centred practices. Based on an ethnographic study of a Dutch fertility clinic, outspoken in its aims to provide patient-centred medicine and to empower clients, this paper addresses how patient-centred medicine affects couples' decision-making to use IVF and related reproductive technologies. The author contends that while patient-centred practices facilitate informed decision-making and support couples emotionally, they may also have unintended disciplining and normalizing effects. The information and support provided, the trust couples have in clinic staff, the ongoing visualization of conception mediated by medical technology--all can be seen as practices that strengthen lay people's 'medical gaze' in how they come to view their bodies, fertility problems and possible solutions. These unintended effects are labelled 'the ambiguity of patient-centeredness' as they (may) interfere with processes of autonomous decision-making.

  9. Transformation of the nitrogen cycle: recent trends, questions, and potential solutions.

    PubMed

    Galloway, James N; Townsend, Alan R; Erisman, Jan Willem; Bekunda, Mateete; Cai, Zucong; Freney, John R; Martinelli, Luiz A; Seitzinger, Sybil P; Sutton, Mark A

    2008-05-16

    Humans continue to transform the global nitrogen cycle at a record pace, reflecting an increased combustion of fossil fuels, growing demand for nitrogen in agriculture and industry, and pervasive inefficiencies in its use. Much anthropogenic nitrogen is lost to air, water, and land to cause a cascade of environmental and human health problems. Simultaneously, food production in some parts of the world is nitrogen-deficient, highlighting inequities in the distribution of nitrogen-containing fertilizers. Optimizing the need for a key human resource while minimizing its negative consequences requires an integrated interdisciplinary approach and the development of strategies to decrease nitrogen-containing waste.

  10. Third world programs confront adolescent fertility.

    PubMed

    1978-08-01

    Recently, there have been efforts to identify workable youth programs and effective research projects that could deal with the problem of adolescent fertility. Typical objectives identified at various conferences concerned with this problem included the following: 1) focus attention on the adverse medical and socioeconomic efforts of early pregnancy; 2) draw attention to the current dimensions of adolescent fertility and its changing patterns; 3) encourage development of programs; and 4) impress decision makers with the importance of programs for adolescents. These conferences express a sense of urgency in developing programs before teen-age pregnancy reaches epidemic proportions. Most of the projects already underway are still pilot efforts and have an impact on a very small sector of the population. Yet, they are positive steps toward a solution of the rising problems of adolescent fertility and help to identify workable solutions. A few of these projects -- underway in Colombia, Argentina, Chile, Cost Rica, Guatemala and Mexico -- are reviewed. The consensus of all conferences held to date has been that cross-cultural interchanges is crucial to the spread of programs and ideas that can be adapted to local conditions. 2 key recommendations have emerged from a meeting of donor and support agencies held in Washington, D.C. in May: 1) a major conference should take place during the International Year of the Child (1979) that would focus on early sexual activity and fertility and 2) an Adolescent Fertility Council should be appointed. An Adolescent Fertility Council would provide a structure to correlate and stimulate interaction, while recognizing that country and culture specific programs are essential.

  11. [Effects of migration on the fertility component of urban growth: the case of Tunis].

    PubMed

    Picouet, M R

    1983-01-01

    The relationships among fertility, migration, and urban growth are explored using data from a survey of migration and employment in the city of Tunis, Tunisia. The survey, undertaken in 1972 and 1973, includes data on 1,850 households. Consideration is given to the process of integration of migrant women into urban life and to the consequent changes in their fertility behavior. The problems that these changes in fertility pose for the process of estimating the respective contributions of immigration and fertility to the rate of urban growth are considered.

  12. Diethylstilbestrol (DES) and Cancer

    MedlinePlus

    ... Genetics Services Directory Cancer Prevention Overview Research Diethylstilbestrol (DES) and Cancer On This Page What is DES? ... outlined in the table below. Fertility Problems in DES Daughters ( 7 ) Fertility Complication Hazard Ratio Percent Cumulative ...

  13. Soybean plant growth study conducted using purified protein hydrolysate-based fertilizer made from chrome-tanned leather waste.

    PubMed

    Pati, Anupama; Chaudhary, Rubina

    2015-12-01

    Leather processing discharges enormous amount of chrome containing leather solid waste which creates a major disposal problem. Chrome-tanned leather solid waste is a complex of collagen and chromium. The presence of chromium limits protein application in fertilizer industry. The purified protein hydrolysate with zero chromium could be used as a nitrogen source for fertilizer formulation. In this study, an attempt has been made to employ purified protein hydrolysate derived from chrome-tanned leather shavings (CTLS) in formulation of fertilizer. The formulated fertilizer (1–3 t ha(-1)) is employed as nitrogen source in production of soybean. Plant growth study demonstrates that formulated fertilizer dosage 3 t ha(-1) produced similar effects of commercial fertilizer-treated plants. Application of formulated fertilizer yielded higher seed in plant than commercial fertilizer.

  14. Pubertal induction in hypogonadism: Current approaches including use of gonadotrophins.

    PubMed

    Zacharin, Margaret

    2015-06-01

    Primary disorders of the gonad or those secondary to abnormalities of the hypothalamic pituitary axis result in hypogonadism. The range of health problems of childhood and adolescence that affect this axis has increased, as most children now survive chronic illness, but many have persisting deficits in gonadal function as a result of their underlying condition or its treatment. An integrated approach to hormone replacement is needed to optimize adult hormonal and bone health, and to offer opportunities for fertility induction and preservation that were not considered possible in the past. Timing of presentation ranges from birth, with disorders of sexual development, through adolescent pubertal failure, to adult fertility problems. This review addresses diagnosis and management of hypogonadism and focuses on new management strategies to address current concerns with fertility preservation. These include Turner syndrome, and fertility presevation prior to childhood cancer treatment. New strategies for male hormone replacement therapy that may impinge upon future fertility are emphasized. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. Ecological variation in wealth–fertility relationships in Mongolia: the ‘central theoretical problem of sociobiology’ not a problem after all?

    PubMed Central

    Alvergne, Alexandra; Lummaa, Virpi

    2014-01-01

    The negative wealth–fertility relationship brought about by market integration remains a puzzle to classic evolutionary models. Evolutionary ecologists have argued that this phenomenon results from both stronger trade-offs between reproductive and socioeconomic success in the highest social classes and the comparison of groups rather than individuals. Indeed, studies in contemporary low fertility settings have typically used aggregated samples that may mask positive wealth–fertility relationships. Furthermore, while much evidence attests to trade-offs between reproductive and socioeconomic success, few studies have explicitly tested the idea that such constraints are intensified by market integration. Using data from Mongolia, a post-socialist nation that underwent mass privatization, we examine wealth–fertility relationships over time and across a rural–urban gradient. Among post-reproductive women, reproductive fitness is the lowest in urban areas, but increases with wealth in all regions. After liberalization, a demographic–economic paradox emerges in urban areas: while educational attainment negatively impacts female fertility in all regions, education uniquely provides socioeconomic benefits in urban contexts. As market integration progresses, socio-economic returns to education increase and women who limit their reproduction to pursue education get wealthier. The results support the view that selection favoured mechanisms that respond to opportunities for status enhancement rather than fertility maximization. PMID:25320175

  16. Indonesian couple’s pregnancy ambivalence and contraceptive use

    PubMed Central

    Barden-O'Fallon, Janine L.; Speizer, Ilene S.

    2013-01-01

    CONTEXT: Recognizing pregnancy ambivalence is important for family planning policy and programming efforts. Most studies on pregnancy ambivalence are based on data from women; using partner’s perceived pregnancy intentions whenever partners are considered. This study examines couple’s pregnancy ambivalence and the association with contraceptive use in Indonesia. METHOD: Matched couple data from the 2002-2003 Indonesia Demographic and Health Survey are used to examine contraceptive use, fertility desires, and responses to whether a pregnancy in the next few weeks would be a big problem, small problem or no problem. Inconsistent fertility desires and responses to the problem question are used to define ambivalence. Response patterns and concordance between partners is evaluated. Multivariate logistic regression analyses are used to assess whether couple’s pregnancy ambivalence is associated with contraceptive use. RESULTS: 71% of husbands and 54% of wives report that a pregnancy in the next few weeks would be “no problem.” Couple’s concordance on the problem question is 63% (kappa statistic = 0.26) among contraceptive users and 61% (0.24) among non-users. In the multivariate analysis, couples who were discordant on the problem question were 24% less likely to use contraception than were couples in which both partners agreed a pregnancy would be a big or small problem. Results were not statistically significant at p≥0.05 in a model with a disaggregated variable on couple’s discordance that identified which partner was ambivalent; this might be related to small cell sizes. Contraceptive use was also less likely for couples with discordant fertility desires. CONCLUSION: Husbands and wives influence each other’s fertility attitudes and family planning use. To improve effective contraceptive use and/or continuation, couple’s pregnancy attitudes should be taken into account at the time of screening and method selection. PMID:20403804

  17. The population problem: conceptions and misconceptions.

    PubMed

    Berelson, B

    1971-01-01

    Only 1 in about 110 sex acts results in a conception and 1 in 270 in a live birth. Of all conceptions, 40% result in live births, 5% in stillbirths, and 55% never develop. 1/3 of all known conceptions ends in abortion, spontaneous or induced. It appears that the population problem depends on a small fraction of the potential. Misconceptions of the problem are corrected, and it is emphasized that while no social problem facing the U.S. would be easier with a larger population, demographic factors do not cause all of the other problems. Increasing numbers are not as important as the rate of increase (2% annually worldwide). Today's population problem has been caused by a decreased death rate, not an increased birthrate. There are 2 kinds of countries in the world today: those with a high standard of living and low fertility and those with a low standard of living and high fertility. Most of the uninformed women of the world would not choose to have large numbers of children if they had a choice. Population density is not a problem in itself. Experts disagree, but it is improbable that large numbers of people will die of starvation in the next few decades. Environmental deterioration is more the result of modern economic and technological practices than of demographic factors. Efforts at fertility control are not aimed at minorities in this country and elsewhere. The poor are discriminated against in access to family planning services and abortion. Moslems of developing countries have higher fertility rates than Roman Catholics in developed countries. There would be many social costs if the U.S. were to achieve zero population growth in the near future. The population problem has implications for the future quality of life.

  18. Sperm count. Do we need a new reference value?

    PubMed

    Cardona Maya, Walter

    2010-03-01

    To evaluate the sperm count in fertile men, general population, and infertile men in different regions of the world. Sperm counts were recorded according to their fertility status, proven fertility, men recruited from an andrology/infertility clinic, or healthy men. The average of sperm count in the different studies is lower in infertile men that in fertile men (p>0.001) and in the general population (p>0.001). Based on this analysis the normal sperm count is about 65 million per mL. Using these reference value, only the 25% of the studies in infertile men are above this value, and the 75% studies with fertile men (>65 x 106 sperm/mL).

  19. Improving Water Use Efficiency of Lettuce (Lactuca sativa L.) Using Phosphorous Fertilizers.

    PubMed

    Alkhader, Asad M F; Abu Rayyan, Azmi M

    2013-01-01

    A greenhouse pot experiment was conducted to evaluate the effect of phosphorous (P) fertilizers application to an alkaline calcareous soil on the water use efficiency (WUE) of lettuce cultivar "robinson" of iceberg type. Head fresh and dry weights, total water applied and WUE were affected significantly by the P fertilizer type and rate. P fertilizers addition induced a significant enhancement in the WUE and fresh and dry weights of the crop. A local phosphate rock (PR) applied directly was found to be inferior to the other types of P fertilizers (Mono ammonium phosphate (MAP), Single superphosphate (SSP), and Di ammonium phosphate ((DAP)). MAP fertilizer at 375 and 500 kg P2O5/ha application rates recorded the highest significant values of head fresh weight and WUE, respectively.

  20. Attitudes of fertile and infertile woman towards new reproductive technologies: a case study of Lithuania

    PubMed Central

    2014-01-01

    Background This article analyzes several key issues in the debate: the acceptability of in vitro fertilization; regulation of assisted reproduction and the possibilities of reimbursement for assisted reproduction treatment in Lithuania. Method Two groups of respondents participated in the survey: fertile women and women with fertility disorders. 93 completed questionnaires from women with fertility problems and 146 from women with no fertility problems were analysed. Results Fertile respondents more frequently perceived the embryo as a human being (Fertile Individuals – 68.5%; Infertile Individuals – 35.5%; p < 0.05) and more frequently maintained that assisted reproduction treatment should be only partly reimbursed (Fertile Individuals – 71.3%; Infertile Individuals – 39.8%; p < 0.05). Respondents with fertility disorders more frequently thought that artificial insemination procedure could also be applied to unmarried couples (Fertile Individuals – 51.4%; Infertile Individuals – 76.3%; p < 0.05), and more frequently agreed that there should be no age limit for artificial insemination procedures (Fertile Individuals – 36.3%; Infertile Individuals – 67.7%; p < 0.05). The majority of respondents in both groups (Fertile Individuals – 77.4%; Infertile Individuals – 82.8%; p < 0.05) believed that donation of reproductive cells should be regulated by law. Fertile respondents more frequently considered that strict legal regulation was necessary in case of the number of transferred embryos (Fertile Individuals – 69.2%; Infertile Individuals – 39.8%; p < 0.05) and freezing of embryos (Fertile Individuals – 69.9%; Infertile Individuals – 57.0%; p < 0.05). Conclusion Fertile respondents were statistically more likely to believe that the IVF procedure should be applied only to married couples or women who had a regular partner, the age limit should be defined and the psychological assessment of the couple’s relationship and their readiness for the IVF procedure was necessary. In contrast, infertile couples were statistically more likely than fertile respondents to maintain that the IVF procedure should be fully reimbursed by the state. Fertile respondents were statistically more likely to be categorical with respect to the number of embryos and the freezing of embryos. Meanwhile there is a statistically significant difference in opinions of infertile respondents who were in favour of stricter regulation on donation of reproductive cells. PMID:24684746

  1. Assessing the Availability of Fertility Regulation Methods: Report on a Methodological Study. Scientific Reports, No. 1, February 1977.

    ERIC Educational Resources Information Center

    Rodriguez, German

    The report investigates the problems of assessing the availability of fertility regulation methods in the household and the community. The study originated from the need to evaluate a number of proposed additions to the data collection instruments used by the World Fertility Survey (WFS). The core questionnaire was modified to add the following…

  2. The ambiguity of patient-centred practices: the case of a Dutch fertility clinic

    PubMed Central

    Gerrits, Trudie

    2014-01-01

    When in-vitro fertilization (IVF) was introduced in the 1970s, doctors were criticized for not properly informing prospective users about its possible risks and limited success rates as well as for medicalizing fertility problems. Nowadays, many fertility clinics are seeking to improve their accountability to stakeholders through patient-centred practices. Based on an ethnographic study of a Dutch fertility clinic, outspoken in its aims to provide patient-centred medicine and to empower clients, this paper addresses how patient-centred medicine affects couples’ decision-making to use IVF and related reproductive technologies. The author contends that while patient-centred practices facilitate informed decision-making and support couples emotionally, they may also have unintended disciplining and normalizing effects. The information and support provided, the trust couples have in clinic staff, the ongoing visualization of conception mediated by medical technology – all can be seen as practices that strengthen lay people's ‘medical gaze’ in how they come to view their bodies, fertility problems and possible solutions. These unintended effects are labelled ‘the ambiguity of patient-centeredness’ as they (may) interfere with processes of autonomous decision-making. PMID:24827743

  3. 75 FR 1785 - Agrium Inc. and CF Industries Holding, Inc.; Analysis of the Agreement Containing Consent Orders...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-13

    ... number. Comments also should not include any sensitive health information, such as medical records or other individually identifiable health information. In addition, comments should not include any ``[t... fertilizers: nitrogen, phosphate, and potash, as well as control release fertilizers and micronutrients...

  4. Birch nutrition

    Treesearch

    Merrill C. Hoyle; John C. Bjorkbom

    1969-01-01

    Much of the slow growth and low quality of our birches and other northern hardwoods in New England can be traced to inadequate soil fertility. This problem can be overcome by remedial fertilization, which will enhance the production of healthy, vigorous birch trees.

  5. The Role of Religious Coping Strategies in Predicting Depression among a Sample of Women with Fertility Problems in Shiraz

    PubMed Central

    Aflakseir, Abdulaziz; Mahdiyar, Mansoureh

    2016-01-01

    Background: One of the most common mental health problems among women with infertility problems is depression. Research has shown that religious beliefs and practices can help people to cope with difficult situations. The purpose of this study was to explore the role of different religious coping strategies in predicting depression in a group of infertile women in Shiraz. Methods: A total of 72 women with fertility problems were recruited from several private infertility clinics in Shiraz using convenience sampling. The participants completed the research questionnaires including Beck Depression Inventory and Religious Coping Scale. The Religious Coping Scale consists of five dimensions including practice, active, passive, benevolent reappraisal and negative religious coping. Descriptive statistics (frequency percentage, mean and standard deviation), Pearson’s correlation and simultaneous multiple regression analysis were used for data analysis using SPSS version 16. A p-value less than 0.05 was considered statistically significant. Results: The present study showed that about 30% of women with fertility problems experienced the symptoms of depression. The findings also indicated that the most commonly used religious coping strategy was practice religious coping, while the least commonly used religious coping strategies were passive and negative religious coping. The findings also showed that active religious coping, practice religious coping and benevolent reappraisal coping predicted depression reduction. Conclusion: This study highlights the effect of religious coping on depression reduction of women with fertility problems. In other words, women who used religious coping strategies were less likely to experience depression symptoms. PMID:27141467

  6. Male infertility: an overview of causes and treatment options.

    PubMed

    Leaver, Rachel Busuttil

    2016-10-13

    It is estimated that 3.5 million people in the UK, that is one in every seven couples, have fertility problems. In the past, it was assumed that the cause always lay with the woman. However, developments in science brought a greater understanding of the process of sperm production and conception. It is now known that up to 30% of fertility problems may be because of the man alone and up to 90% of these are down to low sperm count or low sperm quality or both. This paper offers a review of the causes and potential factors that affect male fertility together with an overview of diagnosis, investigation and current treatment options for these men.

  7. Is Low Fertility Really a Problem? Population Aging, Dependency, and Consumption*

    PubMed Central

    2015-01-01

    Longer lives and fertility far below the replacement level of 2.1 births per woman are leading to rapid population aging in many countries. Many observers are concerned that aging will adversely affect public finances and standards of living. Analysis of newly available National Transfer Accounts data for 40 countries shows that fertility well above replacement would typically be most beneficial for government budgets. However, fertility near replacement would be most beneficial for standards of living when the analysis includes the effects of age structure on families as well as governments. And fertility below replacement would maximize per capita consumption when the cost of providing capital for a growing labor force is taken into account. While low fertility will indeed challenge government programs and very low fertility undermines living standards, we find that moderately low fertility and population decline favor the broader material standard of living PMID:25301626

  8. Low Fertility at the Turn of the Twenty-First Century

    PubMed Central

    Morgan, S. Philip; Taylor, Miles G.

    2010-01-01

    In the past few decades, demographic concerns have shifted from rapid population growth fueled by high fertility to concerns of population decline produced by very low, sub-replacement fertility levels. Once considered a problem unique to Europe or developed nations, concerns now center on the global spread of low fertility. Nearly half of the world's population now lives in countries with fertility at or below replacement levels. Further, by the mid-twenty-first century three of four countries now described as developing are projected to reach or slip below replacement fertility. We review the research on low fertility through the predominant frameworks and theories used to explain it. These explanations range from decomposition and proximate determinant frameworks to grand theories on the fundamental causes underlying the pervasiveness and spread of low fertility. We focus on the ability of theory to situate previous and future findings and conclude with directions for furthur research. PMID:20376287

  9. Ecological variation in wealth-fertility relationships in Mongolia: the 'central theoretical problem of sociobiology' not a problem after all?

    PubMed

    Alvergne, Alexandra; Lummaa, Virpi

    2014-12-07

    The negative wealth-fertility relationship brought about by market integration remains a puzzle to classic evolutionary models. Evolutionary ecologists have argued that this phenomenon results from both stronger trade-offs between reproductive and socioeconomic success in the highest social classes and the comparison of groups rather than individuals. Indeed, studies in contemporary low fertility settings have typically used aggregated samples that may mask positive wealth-fertility relationships. Furthermore, while much evidence attests to trade-offs between reproductive and socioeconomic success, few studies have explicitly tested the idea that such constraints are intensified by market integration. Using data from Mongolia, a post-socialist nation that underwent mass privatization, we examine wealth-fertility relationships over time and across a rural-urban gradient. Among post-reproductive women, reproductive fitness is the lowest in urban areas, but increases with wealth in all regions. After liberalization, a demographic-economic paradox emerges in urban areas: while educational attainment negatively impacts female fertility in all regions, education uniquely provides socioeconomic benefits in urban contexts. As market integration progresses, socio-economic returns to education increase and women who limit their reproduction to pursue education get wealthier. The results support the view that selection favoured mechanisms that respond to opportunities for status enhancement rather than fertility maximization. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

  10. Embryology of Maldives clownfish, Amphiprion nigripes (Amphiprioninae)

    NASA Astrophysics Data System (ADS)

    Ghosh, Swagat; Kumar, Thipramalai Thankappanpillai Ajith; Balasubramanian, Thangavel

    2012-06-01

    This study investigated the embryonic development of Maldives clownfish Amphiprion nigripes under natural conditions (28-30°C) at a lagoon of Agatti Island, Lakshadweep, India. The newly deposited fish egg was capsule-shaped and orange-red, with a (0.73 ± 0.04) mm3 yolk containing 5-10 fat globules. The embryonic development of fertilized eggs was divided into 26 stages and the time elapsing for each stage was recorded. Results showed that the cleavage was rapid, with the first division observed 1 h 20 min after fertilization. Blastulation occurred 4 h later, followed by gastrulation 12 h after fertilization, with a yolk volume of (0.61 ± 0.06) mm3. The organogenesis process started 22 h after fertilization when the blastopores closed and notochord formation began. The embryonic stage was recorded 24 h later, with the appearance of forebrain, midbrain, hindbrain, melanophores on yolk-sac and 22 somites, and a decreased yolk volume of (0.54 ± 0.08) mm3. Other organs developed well 31 h after fertilization, whereas the heart started beating and blood circulation began 78 h later. Red pigmentation (erytrophores) appeared 96 h after fertilization, with a small yolk volume of (0.22 ± 0.02) mm3. Mouth developed well and eyes were noticeable 120 h later, with head, pectoral fin and tail frequently moving 144 h after fertilization. The embryo reached the pre-hatching stage 168 h later and started to hatch after 170-180 h incubation. This study first detailed the embryonic development and yolk absorption of A. nigripes under natural conditions.

  11. Thyroglobulin autoantibodies: is there any added value in the detection of thyroid autoimmunity in women consulting for fertility treatment?

    PubMed

    Unuane, David; Velkeniers, Brigitte; Anckaert, Ellen; Schiettecatte, Johan; Tournaye, Herman; Haentjens, Patrick; Poppe, Kris

    2013-08-01

    Thyroid autoimmunity (TAI) is frequent in infertile women, but to what extent thyroglobulin autoantibodies (Tg-Abs) contribute to TAI is unclear in the literature. The aims of the present study were to determine the prevalence of TAI in women consulting for fertility problems and to investigate the impact of isolated Tg-Abs, isolated thyroid peroxidase autoantibodies (TPO-Abs), and the presence of both autoantibody types on thyroid function. Furthermore, thyroid function was compared between women with and without TAI and between infertile and fertile women. A cross-sectional data analysis nested within an ongoing prospective cohort study was performed in order to determine the prevalence of TAI in unselected women consulting our tertiary referral center for reproductive medicine (CRM). The women underwent a determination of serum thyrotropin (TSH), free thyroxine (FT4), TPO-Abs, and Tg-Abs. The cause of infertility, age, body-mass index (BMI), and smoking habits were recorded. The prevalence of TAI was 16% (163/992). In 8% of cases, both types of autoantibodies were present, in 5% isolated positive Tg-Abs were found, and 4% had isolated positive TPO-Abs (p=0.025 and p=0.003 respectively). The prevalence of TAI was significantly higher in infertile women as compared to that in fertile controls (19% vs. 13%; p=0.047). The median serum TSH level was significantly higher in the women with TAI and with isolated positive Tg-Abs compared to that in women without TAI (1.83 [1.44] and 1.90 [0.85] vs. 1.47 [0.94] mIU/L; p<0.001 respectively). The median FT4, age, BMI, and smoking habits were comparable between the study groups. The prevalence of TAI was higher in infertile women as compared to fertile women consulting our CRM. Five percent of the women had isolated positive Tg-Abs and a significantly higher serum TSH compared to that in women without TAI.

  12. Thyroglobulin Autoantibodies: Is There Any Added Value in the Detection of Thyroid Autoimmunity in Women Consulting for Fertility Treatment?

    PubMed Central

    Unuane, David; Velkeniers, Brigitte; Anckaert, Ellen; Schiettecatte, Johan; Tournaye, Herman; Haentjens, Patrick

    2013-01-01

    Background Thyroid autoimmunity (TAI) is frequent in infertile women, but to what extent thyroglobulin autoantibodies (Tg-Abs) contribute to TAI is unclear in the literature. The aims of the present study were to determine the prevalence of TAI in women consulting for fertility problems and to investigate the impact of isolated Tg-Abs, isolated thyroid peroxidase autoantibodies (TPO-Abs), and the presence of both autoantibody types on thyroid function. Furthermore, thyroid function was compared between women with and without TAI and between infertile and fertile women. Methods A cross-sectional data analysis nested within an ongoing prospective cohort study was performed in order to determine the prevalence of TAI in unselected women consulting our tertiary referral center for reproductive medicine (CRM). The women underwent a determination of serum thyrotropin (TSH), free thyroxine (FT4), TPO-Abs, and Tg-Abs. The cause of infertility, age, body-mass index (BMI), and smoking habits were recorded. Results The prevalence of TAI was 16% (163/992). In 8% of cases, both types of autoantibodies were present, in 5% isolated positive Tg-Abs were found, and 4% had isolated positive TPO-Abs (p=0.025 and p=0.003 respectively). The prevalence of TAI was significantly higher in infertile women as compared to that in fertile controls (19% vs. 13%; p=0.047). The median serum TSH level was significantly higher in the women with TAI and with isolated positive Tg-Abs compared to that in women without TAI (1.83 [1.44] and 1.90 [0.85] vs. 1.47 [0.94] mIU/L; p<0.001 respectively). The median FT4, age, BMI, and smoking habits were comparable between the study groups. Conclusions The prevalence of TAI was higher in infertile women as compared to fertile women consulting our CRM. Five percent of the women had isolated positive Tg-Abs and a significantly higher serum TSH compared to that in women without TAI. PMID:23405888

  13. Do fertility intentions predict subsequent behavior? Evidence from Peninsular Malaysia.

    PubMed

    Tan, P C; Tey, N P

    1994-01-01

    Data from the 1984 Malaysian Population and Family Survey were matched with birth registration records for 1985-87 to determine the accuracy of statements regarding desired family size that were reported in a household survey in predicting subsequent reproductive behavior. The findings of this study were that stated fertility intention provides fairly accurate forecasts of fertility behavior in the subsequent period. In other words, whether a woman has another child is predicted closely by whether she wanted an additional child. Informational, educational, and motivational activities of family planning programs would, therefore, have greater success in reducing family size if fertility intentions were taken into account.

  14. An improved Brass correlational fertility model.

    PubMed

    Zhang, E; Chen, J

    1995-01-01

    Demographers have for years tried to establish a mathematical model capable of accurately describing patterns of fertility change. William Brass's Gompertz correlational fertility model is based upon a standard age-specific fertility pattern correlated to the age-specific fertility rate of the area under study with the purpose of simulating the actual age-specific fertility rate of the area. While the Brass correlational fertility model has solved many problems in quantitative studies of fertility and has been applied in population simulation and prediction, it has been unsatisfactory in analyzing fertility changes in China. The authors therefore developed a parity-specific correlational model to better reflect the situation of rapid fertility decline in China. This modified model better describes the impact of current family planning policy in China. Moreover, satisfactory results can be obtained by simulating and analyzing fertility in recent years, and major parameters can be identified by using demographically definite and readily manageable indicators. These indicators can clearly reflect the goals of the country's family planning policy, such as the average age at child-bearing, median age at child-bearing, early reproduction ratio, and percentage of the second child.

  15. The Fertility Problem Inventory: measuring perceived infertility-related stress.

    PubMed

    Newton, C R; Sherrard, W; Glavac, I

    1999-07-01

    To develop a reliable, valid instrument to evaluate perceived infertility-related stress. Prospective study. University-affiliated teaching hospital. Consecutively referred patients (1,153 women and 1,149 men) seen for infertility treatment. None. Participants' infertility-related stress was assessed by written questionnaire using the Fertility Problem Inventory. Current levels of anxiety, depression, and marital satisfaction also were determined. Women described greater global stress than men and higher specific stress in terms of social concerns, sexual concerns, and need for parenthood. Both men and women facing male infertility reported higher global stress and more social and sexual concerns than men and women experiencing female infertility. Social, sexual, and relationship concerns related to infertility were more effective predictors of depression and marital dissatisfaction than expressed needs for parenthood or attitudes toward child-free living. The Fertility Problem Inventory provides a reliable measure of perceived infertility-related stress and specific information on five separate domains of patient concern. Patterns of infertility-related stress differed depending on gender, fertility history, and infertility diagnosis. Among patients receiving treatment, social, sexual, and relationship concerns appear central to current distress. Counseling interventions that target these domains appear likely to offer maximal therapeutic benefit.

  16. Dimethyleacetamide improves the cryosurvivability of Indian red jungle fowl (Gallus gallus murghi) sperm.

    PubMed

    Rakha, B A; Ansari, M S; Akhter, S; Zafar, Z; Naseer, A; Hussain, I; Santiago-Moreno, J; Blesbois, E

    2017-11-01

    It was hypothesized that dimethyleacetamide (DMA) can be used as an alternate to glycerol for cryopreservation of Indian red jungle fowl semen. Four concentrations of DMA (4%, 6%, 8% and 10%) in extender were compared with previously optimized cryopreservation protocol based on 20% glycerol (control) for Indian red jungle fowl. Sperm motility, plasma membrane integrity, viability, and acrosome integrity were assessed at the stage of post-dilution, cooling, equilibration, and freeze-thawing. The whole experiment was repeated/replicated for five times independently. Sperm motility, plasma membrane integrity, viability and acrosome integrity were recorded highest (P < 0.05) at post-dilution, cooling, equilibration, and freeze-thawing in extender having 6% DMA compared to control and other experimental extenders. The highest (P < 0.05) recovery rates of all aforementioned parameters were also recorded in extender having 6% DMA; thus, 6% DMA was further compared with control (20% glycerol) for fertility after artificial insemination. Eggs were collected for five days after artificial insemination with semen cryopreserved in extender containing 6% DMA and control. The higher no. of fertilized eggs, fertility, no. of hatched eggs, hatch (%) and hatchability were recorded with semen cryopreserved in extender having 6% DMA compared to control. It is concluded that 6% DMA maintained higher post-thaw quality and fertility of Indian red jungle fowl semen and is a better replacement of glycerol. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Young female cancer patients' experiences with fertility counselling and fertility preservation-a qualitative small-scale study within the Danish health care setting.

    PubMed

    Hoeg, Didde; Schmidt, Lone; Macklon, Kirsten T

    2016-07-14

    Fertility counselling for young women newly diagnosed with cancer is an important field of preconceptional counselling. This qualitative, small-scale study explored how young women newly diagnosed with cancer experienced specialized fertility preservation counselling and treatment in the public Danish health care system. Semi-structured, in-depth interviews were conducted with five women below 40 years recently diagnosed with cancer. All women received fertility counselling by a fertility specialist at the Fertility Clinic, University Hospital of Copenhagen, Denmark before initiation of cancer treatment. Participants were interviewed at a place chosen by them, and interviews were recorded and transcribed verbatim. Data were analysed using systematic text condensation developed by Malterud and inspired by Giorgi's phenomenological analysis. None of the participants were aware that chemotherapy could destroy their eggs. The participants described how specialized fertility counselling and fertility preservation contributed to a belief in life after cancer, which gave them hope that they would survive their cancer disease. Further, the women described how the possibility of fertility preservation removed a huge concern and enabled them to concentrate on their cancer treatment and on getting better. Overall, the specialized fertility counselling and treatment to preserve fertility was highly valued. The women felt it gave them a choice about their future fertility. The fertility expert presented the various fertility-preserving scenarios, and the women were content that they had an actual choice.

  18. Young female cancer patients’ experiences with fertility counselling and fertility preservation—a qualitative small-scale study within the Danish health care setting

    PubMed Central

    Hoeg, Didde; Schmidt, Lone; Macklon, Kirsten T.

    2016-01-01

    Introduction Fertility counselling for young women newly diagnosed with cancer is an important field of preconceptional counselling. This qualitative, small-scale study explored how young women newly diagnosed with cancer experienced specialized fertility preservation counselling and treatment in the public Danish health care system. Methods Semi-structured, in-depth interviews were conducted with five women below 40 years recently diagnosed with cancer. All women received fertility counselling by a fertility specialist at the Fertility Clinic, University Hospital of Copenhagen, Denmark before initiation of cancer treatment. Participants were interviewed at a place chosen by them, and interviews were recorded and transcribed verbatim. Data were analysed using systematic text condensation developed by Malterud and inspired by Giorgi’s phenomenological analysis. Results None of the participants were aware that chemotherapy could destroy their eggs. The participants described how specialized fertility counselling and fertility preservation contributed to a belief in life after cancer, which gave them hope that they would survive their cancer disease. Further, the women described how the possibility of fertility preservation removed a huge concern and enabled them to concentrate on their cancer treatment and on getting better. Conclusion Overall, the specialized fertility counselling and treatment to preserve fertility was highly valued. The women felt it gave them a choice about their future fertility. The fertility expert presented the various fertility-preserving scenarios, and the women were content that they had an actual choice. PMID:27413812

  19. Rising up: Fertility trends in Egypt before and after the revolution

    PubMed Central

    el-Shitany, Atef; Sholkamy, Hania; Benova, Lenka

    2018-01-01

    In 2014, Egypt’s Demographic and Health Survey (EDHS) documented an increase in the total fertility rate (TFR) to 3.5, up from a low of 3.0 recorded by the 2008 EDHS. The increase has been anecdotally attributed to the social upheaval following Egypt’s January 2011 revolution, but little is known about when fertility first began to increase and among which sub-groups of women. Using birth histories from seven rounds of EDHS (1992–2014), this study reconstructed fertility rates for single years from 1990–2013 and examined patterns of childbearing in five-year birth cohorts of women. We found that the decline in fertility reversed in 2007, earlier than postulated, plateaued and then increased again in 2013. The increase in TFR coincided with a convergence of fertility rates across education levels, and there is evidence of a shift toward childbearing at younger ages among more educated women, which may be inflating period measures of fertility. PMID:29346389

  20. Comprehensive proteomic analysis of bovine spermatozoa of varying fertility rates and identification of biomarkers associated with fertility.

    PubMed

    Peddinti, Divyaswetha; Nanduri, Bindu; Kaya, Abdullah; Feugang, Jean M; Burgess, Shane C; Memili, Erdogan

    2008-02-22

    Male infertility is a major problem for mammalian reproduction. However, molecular details including the underlying mechanisms of male fertility are still not known. A thorough understanding of these mechanisms is essential for obtaining consistently high reproductive efficiency and to ensure lower cost and time-loss by breeder. Using high and low fertility bull spermatozoa, here we employed differential detergent fractionation multidimensional protein identification technology (DDF-Mud PIT) and identified 125 putative biomarkers of fertility. We next used quantitative Systems Biology modeling and canonical protein interaction pathways and networks to show that high fertility spermatozoa differ from low fertility spermatozoa in four main ways. Compared to sperm from low fertility bulls, sperm from high fertility bulls have higher expression of proteins involved in: energy metabolism, cell communication, spermatogenesis, and cell motility. Our data also suggests a hypothesis that low fertility sperm DNA integrity may be compromised because cell cycle: G2/M DNA damage checkpoint regulation was most significant signaling pathway identified in low fertility spermatozoa. This is the first comprehensive description of the bovine spermatozoa proteome. Comparative proteomic analysis of high fertility and low fertility bulls, in the context of protein interaction networks identified putative molecular markers associated with high fertility phenotype.

  1. Comprehensive proteomic analysis of bovine spermatozoa of varying fertility rates and identification of biomarkers associated with fertility

    PubMed Central

    Peddinti, Divyaswetha; Nanduri, Bindu; Kaya, Abdullah; Feugang, Jean M; Burgess, Shane C; Memili, Erdogan

    2008-01-01

    Background Male infertility is a major problem for mammalian reproduction. However, molecular details including the underlying mechanisms of male fertility are still not known. A thorough understanding of these mechanisms is essential for obtaining consistently high reproductive efficiency and to ensure lower cost and time-loss by breeder. Results Using high and low fertility bull spermatozoa, here we employed differential detergent fractionation multidimensional protein identification technology (DDF-Mud PIT) and identified 125 putative biomarkers of fertility. We next used quantitative Systems Biology modeling and canonical protein interaction pathways and networks to show that high fertility spermatozoa differ from low fertility spermatozoa in four main ways. Compared to sperm from low fertility bulls, sperm from high fertility bulls have higher expression of proteins involved in: energy metabolism, cell communication, spermatogenesis, and cell motility. Our data also suggests a hypothesis that low fertility sperm DNA integrity may be compromised because cell cycle: G2/M DNA damage checkpoint regulation was most significant signaling pathway identified in low fertility spermatozoa. Conclusion This is the first comprehensive description of the bovine spermatozoa proteome. Comparative proteomic analysis of high fertility and low fertility bulls, in the context of protein interaction networks identified putative molecular markers associated with high fertility phenotype. PMID:18294385

  2. Nutrient uptake of NPK and result of some rice varieties in tidal land by using combination of organic and inorganic fertilizer

    NASA Astrophysics Data System (ADS)

    Marlina, Neni; Rompas, Joni Phillep; Marlina, Musbik

    2017-09-01

    Rice planting in tidal land has two main problems: iron (Fe) which has the potential to poison rice and low nutrient availability. Azospirillum enriched chicken manure and phosphate solvent bacteria (Biological Organic Fertilizer = BOF) is an option to overcome iron toxicity and as a source of nutrition. The objective of the study was to obtain a combination of biological organic fertilizers and balanced inorganic fertilizers in reducing doses of inorganic fertilizers, increasing NPK nutrient uptake and yield of several rice varieties in tidal land. This research used Factorial RAK with 25 treatment combinations that were repeated three times. Factor I is a combination of BOF and anorganic fertilizer with 5 levels of treatment (no inorganic fertilizers, BOF 400 kg / ha with inorganic fertilizer 25% NPK, BOF 400 kg / ha with inorganic fertilizer 50% NPK and BOF 400 kg / ha with fertilizer Inorganic 75% NPK). Factor II is several rice varieties (IPB 4S, Martapura, Margasari, Inpara 5, Inpara 7). The results showed that organic fertilizer 400 kg / ha can reduce the use of inorganic fertilizer by 75% of NPK fertilizer. The highest NPK nutrient absorption is in the treatment of organic fertilizer 400 kg / ha and inorganic fertilizer 25% of NPK fertilizer. Production of biological organic fertilizer 400 kg / ha with inorganic fertilizer 25% NPK and 4B IPB varieties 727.77% higher when compared with without the provision of organic fertilizer with Inpara 5 varieties.

  3. Sea urchin fertilization in a warm, acidified and high pCO2 ocean across a range of sperm densities.

    PubMed

    Byrne, Maria; Soars, Natalie; Selvakumaraswamy, Paulina; Dworjanyn, Symon A; Davis, Andrew R

    2010-05-01

    Marine invertebrate gametes are being spawned into an ocean simultaneously warming, acidifying and increasing in pCO(2). Decreased pH/increased pCO(2) narcotizes sperm indicating that acidification may impair fertilization, exacerbating problems of sperm limitation, with dire implications for marine life. In contrast, increased temperature may have a stimulatory effect, enhancing fertilization. We investigated effects of ocean change on sea urchin fertilization across a range of sperm densities. We address two predictions: (1) low pH/increased pCO(2) reduces fertilization at low sperm density and (2) increased temperature enhances fertilization, buffering negative effects of acidification and increased pCO(2). Neither prediction was supported. Fertilization was only affected by sperm density. Increased acidification and pCO(2) did not reduce fertilization even at low sperm density and increased temperature did not enhance fertilization. It is important to identify where vulnerabilities lie across life histories and our results indicate that sea urchin fertilization is robust to climate change stressors. However, developmental stages may be vulnerable to ocean change. Copyright 2009 Elsevier Ltd. All rights reserved.

  4. Oral administration of supplementary biotin differentially influences the fertility rate and oviductal expression of avidin and avidin-related protein-2 in low- and high-fertility broiler line hens.

    PubMed

    Daryabari, H; Akhlaghi, A; Zamiri, M J; Pirsaraei, Z Ansari; Mianji, G Rahimi; Deldar, H; Eghbalian, A N

    2015-02-01

    Probable involvement of avidin and avidin-related protein-2 (AVR2) in sperm viability in the sperm storage tubules of turkeys has been suggested. The high affinity of biotin to avidin and its analogs is also well documented. The present study aimed to determine the effect of oral biotin on reproductive performance and oviductal mRNA expression of avidin and AVR2 in 2 broiler hen lines with different fertility rates. Low-fertility (line B) and high-fertility (line D) hens (n=144) were randomly allotted to receive 0 (T0), 0.30 (T1), or 0.45 (T2) mg/L biotin in drinking water from 30 through 33 wk of age. The reproductive performance of the hens was evaluated using artificial insemination. At the end of the treatment period, 24 hens per line were killed to assay the expression of avidin and AVR2 in the uterovaginal junction. Supplementary biotin increased egg production from 73.5% for T0 to 87.8% for T2. Hens administered with biotin in line B, but not in line D, showed an increase (8.4%) in fertility rate. Hatchability, chick quality, and overall embryonic mortality were not different among the experimental groups. Real-time PCR data showed that both avidin (P=0.0013) and AVR2 (P<0.0001) expressions were influenced by a biotin×line interaction effect, where low-fertility line B hens receiving the high biotin level recorded respectively a 3.9 and 15.3% increase in avidin and AVR2 mRNA expression, although biotin did not affect these traits in line D hens. Control hens in line D had a dramatically higher AVR2 expression record (7.4-fold) compared with the control hens in line B. The correlation coefficients of fertility rate and avidin expression were 0.73 and 0.66 in lines B and D, respectively. However, the correlation of fertility and AVR2 (r=0.65) was significant for line D hens only. Overall, fertility rate and oviductal expression of avidin and AVR2 were dichotomously affected by oral biotin in low- and high-fertility line hens, where only low-fertility birds showed improvements in these attributes. © 2015 Poultry Science Association Inc.

  5. The Role Of Staphylococcus Haemolyticus In Men Infertility

    NASA Astrophysics Data System (ADS)

    AL-Ghizzawi, Ghaed’a. J.; Jomaa, Zahraa K.

    2018-05-01

    A total of 80 samples of seminal fluid from infertile men who were admitted to clinics and attended laboratories in Omara City during the period from 1 June 2016 to 1 December 2016, samples were subjected to semen analysis as recommended by WHO. The age of patients was from 20 – 59 year. Another 25 semen samples were collected from fertilized men considered as the control group. For this purpose seminal fluid were cultured on MacConkey agar, Blood agar, Chocolate agar. Within the 80 samples recorded S. haemolyticus appeared in 14 cases and the rate of infection was 18%, all strains was diagnosed by Vitek system 2 Double. The highest percent (64%) was recorded in the age group 30 – 39. Primary infertility recorded 94% while 6% was recorded for secondary infertility. Also, different species of bacterial isolates were identified in 32 cases by Vitek system 2 Double. The bacterial infection of the male genital system affected fertility.

  6. 'Just because a doctor says something, doesn't mean that [it] will happen': self-perception as having a Fertility Problem among Infertility Patients.

    PubMed

    Leyser-Whalen, Ophra; Greil, Arthur L; McQuillan, Julia; Johnson, Katherine M; Shrefffler, Karina M

    2018-03-01

    Only some individuals who have the medically defined condition 'infertility' adopt a self-definition as having a fertility problem, which has implications for social and behavioural responses, yet there is no clear consensus on why some people and not others adopt a medical label. We use interview data from 28 women and men who sought medical infertility treatment to understand variations in self-identification. Results highlight the importance of identity disruption for understanding the dialectical relationship between medical contact and self-identification, as well as how diagnosis acts both as a category and a process. Simultaneously integrating new medical knowledge from testing and treatment with previous fertility self-perceptions created difficulty for settling on an infertility self-perception. Four response categories emerged for adopting a self-perception of having a fertility problem: (i) the non-adopters - never adopting the self-perception pre- or post-medical contact; (ii) uncertain - not being fully committed to the self-perception pre- or post-medical contact; (iii) assuming the label - not having prior fertility concerns but adopting the self-perception post-medical contact; and (iv) solidifying a tentative identity - not being fully committed to a self-perception pre-medical contact, but fully committed post-medical contact. (A virtual abstract of this paper can be viewed at: https://www.youtube.com/channel/UC_979cmCmR9rLrKuD7z0ycA). © 2017 Foundation for the Sociology of Health & Illness.

  7. ICAR guidelines for recording, evaluation and genetic improvement of female fertility in dairy cattle

    USDA-ARS?s Scientific Manuscript database

    Fertility refers to the ability of a cow to conceive and maintain pregnancy within a specific time period, and is of substantial economic importance in the dairy industry because lactations begin with the birth of a calf. Culling rates due to infertility are much higher than two or three decades ago...

  8. [Use of fertility drugs and risk of breast cancer].

    PubMed

    Pomeranz, Meir

    2013-10-01

    The strong desire to bring children into the world is the foundation of human existence. Fertility problems arise in approximately 10% of the population. The literature presents controversies regarding whether fertility treatment and ovarian hyperstimulation can be harmful to the patient. Can high estrogen levels that accompany the treatment cause or promote breast cancer? Dr. Riskin-Mashiach in her article: "Infertility, fertility treatment and breast cancer risk", reviews recent articles on the subject and concludes that most studies do not indicate a direct link but larger studies are needed to verify the safety of these treatments for patients.

  9. Determination of phosphate phases in sewage sludge ash-based fertilizers by Raman microspectroscopy.

    PubMed

    Vogel, Christian; Adam, Christian; McNaughton, Don

    2013-09-01

    The chemical form of phosphate phases in sewage sludge ash (SSA)-based fertilizers was determined by Raman microspectroscopy. Raman mapping with a lateral resolution of 5 × 5 μm(2) easily detected different compounds present in the fertilizers with the help of recorded reference spectra of pure substances. Quartz and aluminosilicates showed Raman bands in the range of 450-520 cm(-1). Phosphates with apatite structure and magnesium triphosphate were determined at around 960 and 980 cm(-1), respectively. Furthermore, calcium/magnesium pyrophosphates were detected in some samples.

  10. [Research advances on regulating soil nitrogen loss by the type of nitrogen fertilizer and its application strategy.

    PubMed

    Zhou, Wei; Lyu, Teng Fei; Yang, Zhi Ping; Sun, Hong; Yang, Liang Jie; Chen, Yong; Ren, Wan Jun

    2016-09-01

    Unreasonable application of nitrogen fertilizer to cropland decreases nitrogen use efficiency of crop. A large amount of nitrogen loss to environment through runoff, leaching, ammonia volati-lization, nitrification-denitrification, etc., causes water and atmospheric pollution, poses serious environmental problems and threatens human health. The type of nitrogen fertilizer and its application rate, time, and method have significant effects on nitrogen loss. The primary reason for nitrogen loss is attributed to the supersaturated soil nitrogen concentration. Making full use of environmental nitrogen sources, reducing the application rate of chemical nitrogen fertilizers, applying deep placement fertilizing method, and applying organic fertilizers with chemical nitrogen fertilizers, are effective practices for reducing nitrogen loss and improving nitrogen use efficiency. It is suggested that deve-loping new high efficiency nitrogen fertilizers, enhancing nitrogen management, and strengthening the monitoring and use of environmental nitrogen sources are the powerful tools to decrease nitrogen application rate and increase efficiency of cropland.

  11. Historical nitrogen fertilizer use in agricultural ecosystems of the contiguous United States during 1850-2015: application rate, timing, and fertilizer types

    NASA Astrophysics Data System (ADS)

    Cao, Peiyu; Lu, Chaoqun; Yu, Zhen

    2018-06-01

    A tremendous amount of anthropogenic nitrogen (N) fertilizer has been applied to agricultural lands to promote crop production in the US since the 1850s. However, inappropriate N management practices have caused numerous ecological and environmental problems which are difficult to quantify due to the paucity of spatially explicit time-series fertilizer use maps. Understanding and assessing N fertilizer management history could provide important implications for enhancing N use efficiency and reducing N loss. In this study, we therefore developed long-term gridded maps to depict crop-specific N fertilizer use rates, application timing, and the fractions of ammonium N (NH4+-N) and nitrate N (NO3--N) used across the contiguous US at a resolution of 5 km × 5 km during the period from 1850 to 2015. We found that N use rates in the US increased from 0.22 g N m-2 yr-1 in 1940 to 9.04 g N m-2 yr-1 in 2015. Geospatial analysis revealed that hotspots for N fertilizer use have shifted from the southeastern and eastern US to the Midwest, the Great Plains, and the Northwest over the past century. Specifically, corn in the Corn Belt region received the most intensive N input in spring, followed by the application of a large amount of N in fall, implying a high N loss risk in this region. Moreover, spatial-temporal fraction of NH4+-N and NO3--N varied largely among regions. Generally, farmers have increasingly favored ammonia N fertilizers over nitrate N fertilizers since the 1940s. The N fertilizer use data developed in this study could serve as an essential input for modeling communities to fully assess N addition impacts, and improve N management to alleviate environmental problems. Datasets used in this study are available at https://doi.org/10.1594/PANGAEA.883585.

  12. Late Holocene droughts in the Fertile Crescent recorded in a speleothem from northern Iraq

    NASA Astrophysics Data System (ADS)

    Flohr, Pascal; Fleitmann, Dominik; Zorita, Eduardo; Sadekov, Aleksey; Cheng, Hai; Bosomworth, Matt; Edwards, Lawrence; Matthews, Wendy; Matthews, Roger

    2017-02-01

    Droughts have had large impacts on past and present societies. High-resolution paleoclimate data are essential to place recent droughts in a meaningful historical context and to predict regional future changes with greater accuracy. Such records, however, are very scarce in the Middle East in general, and the Fertile Crescent in particular. Here we present a 2400 year long speleothem-based multiproxy record from Gejkar Cave in northern Iraq. Oxygen and carbon isotopes and magnesium are faithful recorders of effective moisture. The new Gejkar record not only shows that droughts in 1998-2000 and 2007-2010, which have been argued to be a contributing factor to Syrian civil war, were extreme compared to the current mean climate, but they were also superimposed on a long-term aridification trend that already started around or before 950 C.E. (Common Era). This long-term trend is not captured by tree ring records and climate models, emphasizing the importance of using various paleoclimate proxy data to evaluate and improve climate models and to correctly inform policy makers about future hydroclimatic changes in this drought-prone region.

  13. Assessing Long Term Impact of Phosphorus Fertilization on Phosphorus Loadings Using AnnAGNPS

    EPA Science Inventory

    High phosphorus (P) loss from agricultural fields has been an environmental concern because of potential water quality problems in streams and lakes. To better understand the process of P loss and evaluate the different phosphorus fertilization rates on phosphorus losses, the US...

  14. Female employment and fertility in Peninsular Malaysia: the maternal role incompatibility hypothesis reconsidered.

    PubMed

    Mason, K O; Palan, V T

    1981-11-01

    Multivariate analysis of the 1974 Malaysian Fertility and Family Survey tests the hypothesis that an inverse relationship between women's work and fertility occurs only when there are serious conflicts between working and caring for children. The results are only partly consistent with the hypothesis and suggest that normative conflicts between working and mothering affect the employment-fertility relationship in Malaysia more than spacio-temporal conflicts do. The lack of consistent evidence for the hypothesis, as well as some conceptual problems, lead us to propose an alternative framework for understanding variation in the employment-fertility relationship, both in Malaysia and elsewhere. This framework incorporates ideas from the role incompatibility hypothesis but views the employment-fertility relationship as dependent not just on role conflicts but more generally on the structure of the household's socioeconomic opportunities.

  15. Perception of control, coping and psychological stress of infertile women undergoing IVF.

    PubMed

    Gourounti, Kleanthi; Anagnostopoulos, Fotios; Potamianos, Grigorios; Lykeridou, Katerina; Schmidt, Lone; Vaslamatzis, Grigorios

    2012-06-01

    The study aimed to examine: (i) the association between perception of infertility controllability and coping strategies; and (ii) the association between perception of infertility controllability and coping strategies to psychological distress, applying multivariate statistical techniques to control for the effects of demographic variables. This cross-sectional study included 137 women with fertility problems undergoing IVF in a public hospital. All participants completed questionnaires that measured fertility-related stress, state anxiety, depressive symptomatology, perception of control and coping strategies. Pearson's correlation coefficients were calculated between all study variables, followed by hierarchical multiple linear regression. Low perception of personal and treatment controllability was associated with frequent use of avoidance coping and high perception of treatment controllability was positively associated with problem-focused coping. Multivariate analysis showed that, when controlling for demographic factors, low perception of personal control and avoidance coping were positively associated with fertility-related stress and state anxiety, and problem-appraisal coping was negatively and significantly associated with fertility-related stress and depressive symptomatology scores. The findings of this study merit the understanding of the role of control perception and coping in psychological stress of infertile women to identify beforehand those women who might be at risk of experiencing high stress and in need of support. Copyright © 2012 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

  16. The relationship between perceived stigma, disclosure patterns, support and distress in new attendees at an infertility clinic.

    PubMed

    Slade, P; O'Neill, C; Simpson, A J; Lashen, H

    2007-08-01

    A model suggesting that high perception of stigma is associated with reduced disclosure to others, leading to lower social support and higher distress in new attendees at an infertility clinic is tested. Questionnaires measuring stigmatization (Stigma consciousness questionnaire), disclosure of fertility difficulties (Disclosure questionnaire), social support (Duke-UNC Functional Social Support Questionnaire) and fertility-related [Fertility Problem Inventory (FPI)] and generic distress [Hospital Anxiety and Depression Scale (HADS)] were completed by 87 women and 64 men. Data were analysed by gender comparisons, correlations and path analysis. Women reported higher stigma and disclosure than men. For women, stigma and disclosure were unrelated but in men higher stigma was associated with lower disclosure. Perceptions of stigma were related to low social support for both genders. Social support was negatively related to anxiety, depression and overall infertility distress and showed greater predictive capacity than satisfaction with partner relationship. Testing the model showed that, for men, stigma was linked to lower disclosure and support and higher fertility-related and generic distress. Disclosure itself did not link to support. For women, greater disclosure linked only to higher generic distress. Stigma was directly linked to fertility-related distress and to low perceived support which mediated a relationship with generic distress. Stigma and the wider social context should be considered when supporting people with fertility problems. Greater disclosure may be associated with higher distress in women.

  17. Food production -- problems and prospects.

    PubMed

    Anifowoshe, T O

    1990-03-01

    Improvements are needed in balancing the problems associated with population growth and food production. A review of the problems of rapid population growth and declining food production and suggestions for resolution are given. World population has increased over the past 10 years by 760 million, which is equal to adding the combined population of Africa and South America. Future increases are expected to bring total population to 6.1 billion by the year 2000 and 8.2 billion in 2025 (exponential increases). Food production/capita has declined since 1971 in the world and in Nigeria, particularly in the recent past. The food production problem is technical, environmental, social, political, and economic. Various scientific and technological methods for increasing food production are identified: mechanization, irrigation, use of fertilizers, control of weeds and insects, new varieties of farm animals or high-yielding strains of grain, land reclamation, soil conservation, river basin development, adequate storage facilities, infrastructure development, and birth control. Economic and social approaches involve short-term and long-term strategies in social readjustment and institutional change. For instance, large scale farmers should become contract growers for certain firms. Bureaucratic red tape should be eliminated in institutions which provide agricultural services. Environmental problems need urgent attention. Some of these problems are soil erosion from mechanization, water salinization from irrigation, accumulation of DDT in food and water and animal life from pesticide use, and water pollution from chemical fertilizers. Food production can be increased with more ecologically sound practices. Information about weather and weather forecasting allows for more suitable land management. The influence of rainfall (the amount and distribution) in Nigeria is greater than any other climatic factor. Solar radiation is a significant feature in production of dry matter and yield. Shifting cultivation and land tenure systems should involve conservation farming techniques. organic manures and appropriate use of chemical fertilizers can raise soil fertility. Other problems are identified as the spread of bilharzia and the settlement of nomadic tribes.

  18. [Fertility in the Yanomami population, Sierra Parima (Amazonas Federal Territory, Venezuela)].

    PubMed

    Scholnik, S

    1983-08-01

    This article presents information on the age structure and the level of female fertility obtained on the basis of a sample of the yanomami population (653 individuals) residing in the Venezuelan margin of Sierra Parima. Data was gathered through a survey which had the character of a retrospective demographic investigation, consisting of a series of questions about past events. The survey was conducted almost in its entirety by an American missionary who has resided in the area since 1972. The study took place from March 1981 to March 1982. To estimate the number of births per anum Mortara's method was used. This method consists of plotting on a graph the number of live births according to the mother's age and adjusting the resulting curve so that irregularities disappear. The population observed was very young, over 50% were less than 15 years old and the mean age was 18 years. The total fertility rate reach 7.76 children/woman while the age distribution of rates showed that fertility began at early ages and started to decrease only after age 30. The comparison of the obtained parity averages with existing records of fertility rates suggest that the information given for the year previous to the survey was the most accurate. The importance of maintaining reliable and continuous records of live births is stressed. Results are illustrated in tables and charts.

  19. Does Spinal Analgesia have Advantage over General Anesthesia for Achieving Success in In-Vitro Fertilization?

    PubMed Central

    Aghaamoo, Shahrzad; Azmoodeh, Azra; Yousefshahi, Fardin; Berjis, Katayon; Ahmady, Farahnazsadat; Qods, Kamran; Mirmohammadkhani, Majid

    2014-01-01

    Objective Because of high psychological burden and considerable costs of in-vitro fertilization, it is greatly important to identify all factors that may influence its results. In this study, general anesthesia and spinal analgesia used for oocyte retrieval were compared in terms of success in treating infertility among couples who had undergone in-vitro fertilization at an infertility center in Tehran, Iran. Methods This cohort study that was based on analysis of patient records at Mirza Kochak Khan Hospital, Tehran University of Medical Sciences, in 2008-2009. In this study, the status of chemical pregnancy among those who experienced general anesthesia or spinal anesthesia for in-vitro fertilization for the first time were compared, and the possible effects of clinical and laboratory factors using logistic regression models were considered. Results Considering the number of transferred embryos, underlying cause of infertility and fetus grade, it was found that practicing spinal anesthesia is significantly related to increased chance of chemical pregnancy (adjusted Odds Ratio=2.07; 95% CI: 1.02,4.20; p=0.043). Conclusion According to analysis of recorded data in an infertility treatment center in Iran, it is recommended to use spinal anesthesia instead of general anesthesia for oocyte retrieval to achieve successful in-vitro fertilization outcome. This can be studied and investigated further via a proper multicentric study in the country. PMID:24715934

  20. Does Spinal Analgesia have Advantage over General Anesthesia for Achieving Success in In-Vitro Fertilization?

    PubMed

    Aghaamoo, Shahrzad; Azmoodeh, Azra; Yousefshahi, Fardin; Berjis, Katayon; Ahmady, Farahnazsadat; Qods, Kamran; Mirmohammadkhani, Majid

    2014-03-01

    Because of high psychological burden and considerable costs of in-vitro fertilization, it is greatly important to identify all factors that may influence its results. In this study, general anesthesia and spinal analgesia used for oocyte retrieval were compared in terms of success in treating infertility among couples who had undergone in-vitro fertilization at an infertility center in Tehran, Iran. This cohort study that was based on analysis of patient records at Mirza Kochak Khan Hospital, Tehran University of Medical Sciences, in 2008-2009. In this study, the status of chemical pregnancy among those who experienced general anesthesia or spinal anesthesia for in-vitro fertilization for the first time were compared, and the possible effects of clinical and laboratory factors using logistic regression models were considered. Considering the number of transferred embryos, underlying cause of infertility and fetus grade, it was found that practicing spinal anesthesia is significantly related to increased chance of chemical pregnancy (adjusted Odds Ratio=2.07; 95% CI: 1.02,4.20; p=0.043). According to analysis of recorded data in an infertility treatment center in Iran, it is recommended to use spinal anesthesia instead of general anesthesia for oocyte retrieval to achieve successful in-vitro fertilization outcome. This can be studied and investigated further via a proper multicentric study in the country.

  1. Design and experiment on 2KF-15 type disc cutter and shallow fertilization machine in rubber plantation

    NASA Astrophysics Data System (ADS)

    Deng, Yiguo; Zhang, Yuan; Wang, Yeqin

    2017-12-01

    At present, the trenching and fertilization machine has a serious weed plug problem when trenching and fertilization operation in rubber plantation. So a disc cutter and shallow fertilization machine in rubber plantation named 2KF-15 was designed, the design scheme used the front disc cutter cutting the grass, while using the rear of the disc furrow to trenching, the prototype of a disc anti-plugging trenching and shallow fertilization machine was completed. Afterwards, a series of trenching and fertilization field experiments were carried out, and the results showed that the ditching depth of this machine could achieve from 131 to 176 mm, and the average depth could reach 156 mm, the ditching depth stability coefficient could achieve 90.3%; The fertilizer amount of this machine could achieve from 113.2 to 156.4 kg/hm2, the average fertilizer amount reach 134.2kg/hm2, the fertilizer amount stability coefficient could achieve 89.6%, the fertilizer broken rate was 0%, the fertilizer coverage rate of 98.4%;The situation of fertilizer accumulation occurred less by using this machine, and the fertilization performance was relatively stable. This new designed machine for trenching, fertilization and covering the soil were carried out at the same time. So the number of operations could be effectively reduced. This new designed machine does not only meet the agronomic requirements of rubber plantation fertilization, but also provides a reference for the trenching and fertilization operation in other.

  2. Interactions between observer and stimuli fertility status: Endocrine and perceptual responses to intrasexual vocal fertility cues.

    PubMed

    Ostrander, Grant M; Pipitone, R Nathan; Shoup-Knox, Melanie L

    2018-02-01

    Both men and women find female voices more attractive at higher fertility times in the menstrual cycle, suggesting the voice is a cue to fertility and/or hormonal status. Preference for fertile females' voices provides males with an obvious reproduction advantage, however the advantage for female listeners is less clear. One possibility is that attention to the fertility status of potential rivals may enable women to enhance their own reproductive strategies through intrasexual competition. If so, the response to having high fertility voices should include hormonal changes that promote competitive behavior. Furthermore, attention and response to such cues should vary as a function of the observer's own fertility, which influences her ability to compete for mates. The current study monitored variation in cortisol and testosterone levels in response to evaluating the attractiveness of voices of other women. All 33 participants completed this task once during ovulation then again during the luteal phase. The voice stimuli were recorded from naturally cycling women at both high and low fertility, and from women using hormonal birth control. We found that listeners rated high fertility voices as more attractive compared to low fertility, with the effect being stronger when listeners were ovulating. Testosterone was elevated following voice ratings suggesting threat detection or the anticipation of competition, but no stress response was found. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. Optimization of Nitrogen, Phosphorus, and Potassium Fertilization Rates for Overseeded Perennial Ryegrass Turf on Dormant Bermudagrass in a Transitional Climate

    PubMed Central

    Ihtisham, Muhammad; Fahad, Shah; Luo, Tao; Larkin, Robert M.; Yin, Shaohua; Chen, Longqing

    2018-01-01

    Bermudagrass [Cynodon dactylon (L.) Pers.] turf loss due to severe cold in transitional climates is a major concern. To overcome this problem, warm-season grass is often overseeded with a cool-season turfgrass. In this study, modeling and efficient nutrient management were used to evaluate this problem. A three-factor and five-level central composite rotatable design (CCRD) with a simulation of a regression model was used to optimize fertilization rates. The study investigated the combined effects of fertilization with nitrogen (N), phosphorus (P), and potassium (K) on both the morphological and physiological attributes and on the integrated turf performance (ITP) of overseeded perennial ryegrass (Lolium perenne). Fertilization with N and P significantly increased turf height, density, color, fresh and dry weights, while N, P, and K significantly affected turf cover, quality and winter-kill. The Spring transition was delayed by fertilization with N and P, and accelerated by fertilization with K. Photosynthesis (Pn), transpiration (Tr), and stomatal conductance (Gs) were considerably enhanced by fertilization with N, P, and K. Protein levels and total chlorophyll levels were substantially increased by fertilization with N and P and with N, P, and K, respectively, during a 2-year period. During two separate experiments conducted during 2 consecutive years, the optimal combinations of N, P, and K were N: 30, P: 24, K: 9, and N: 30, P: 27, K: 6 g m−2. The major conclusion of this study is that a balanced nutrient application utilizing N, P, and K is key to enhancing the winter performance of perennial ryegrass. PMID:29713331

  4. What is to be done with surplus embryos? Attitude formation with ambivalence in German fertility patients.

    PubMed

    Kufner, K; Tonne, M; Barth, J

    2009-01-01

    Improved pregnancy rates in IVF have led to increasing numbers of surplus embryos which can potentially be used for purposes like donation to another infertile couple or further research. Individuals report high levels of ambivalence concerning the donation of surplus embryos. This study examined which strategies infertile patients use to deal with this ambivalence when asked to evaluate potential dispositions of surplus embryos created during IVF. Guideline-based interviews with fertility patients were audio-recorded and transcribed verbatim. Following the principle of theoretical sampling, eight interviews were analysed by use of Grounded Theory. Analyses focused on processes of individual attitude formation. Strategies for handling ambivalence during attitude formation were identified: the six strategies comprise cognitive and communicative strategies, and were integrated into a model of attitude formation under ambivalence. As ambivalence is a relevant phenomenon in attitude formation within IVF treatment, assessment of ambivalence is strongly recommended in social science studies investigating ethical problems in patient care. In the context of informed consent, there is a need for individual counselling which draws attention to the conflicting values during attitude formation. Counsellors should be aware of the signs of and the strategies to deal with ambivalence.

  5. The genetic relationship between commencement of luteal activity and calving interval, body condition score, production, and linear type traits in Holstein-Friesian dairy cattle.

    PubMed

    Royal, M D; Pryce, J E; Woolliams, J A; Flint, A P F

    2002-11-01

    The decline of fertility in the UK dairy herd and the unfavorable genetic correlation (r(a)) between fertility and milk yield has necessitated the broadening of breeding goals to include fertility. The coefficient of genetic variation present in fertility is of similar magnitude to that present in production traits; however, traditional measurements of fertility (such as calving interval, days open, nonreturn rate) have low heritability (h2 < 0.05), and recording is often poor, hindering identification of genetically superior animals. An alternative approach is to use endocrine measurements of fertility such as interval to commencement of luteal activity postpartum (CLA), which has a higher h2 (0.16 to 0.23) and is free from management bias. Although CLA has favorable phenotypic correlations with traditional measures of fertility, if it is to be used in a selection index, the genetic correlation (ra) of this trait with fertility and other components of the index must be estimated. The aim of the analyses reported here was to obtain information on the ra between lnCLA and calving interval (CI), average body condition score (BCS; one to nine, an indicator of energy balance estimated from records taken at different months of lactation), production and a number of linear type traits. Genetic models were fitted using ASREML, and r(a) were inferred from genetic regression of lnCLA on sire-predicted transmitting abilities (PTA) for the trait concerned by multiplying the regression coefficient (b) by the ratio of the genetic standard deviations. The inferred r(a) between lnCLA and CI and average BCS were 0.36 and -0.84, respectively. Genetic correlations between InCLA and milk fat and protein yields were all positive and ranged between 0.33 and 0.69. Genetic correlations between InCLA and linear type traits reflecting body structure ranged from -0.25 to 0.15, and between udder characteristics they ranged from -0.16 to 0.05. Thus, incorporation of endocrine parameters of fertility, such as CIA, into a fertility index may offer the potential to improve the accuracy of breeding value prediction for fertility, thus allowing producers to make more informed selection decisions.

  6. [China's population policies: attempting to "resolve the wrong problem"?].

    PubMed

    Ratcliffe, J W

    1989-03-01

    This work argues that international efforts to resolve the population problem have failed primarily because they have been based on misconceptions concerning the definition of the problem and the relationship between population growth and development. The demographic experience of the People's Republic of China since the Revolution is used to illustrate these commonly shared misconceptions. The difficulty of defining the population problem results from differing interpretations of the basic fact that poor population groups tend to have higher fertility rates and faster growth than wealthier population groups. The Western industrial nations maintain that peoples or countries are poor because they have many children; the solution to the problem would require that they be provided access to modern contraception and associated services such as population and family planning education. Many Third World countries argue on the other hand that people have many children because they are poor, a view implying that greater social and economic development will provide the solution. The disagreement as to whether rapid population growth is a cause or a consequence of underdevelopment results in part from viewing overpopulation and underdevelopment as separate and distinct problems. Results of several carefully conducted evaluation studies have demonstrated that very little of the world fertility decline in the late 1960s and early 1970s was attributable to national family planning programs. Research has shown that equitable division of national wealth, education--especially of women, some employment factors such as a lack of opportunities for children, and a reliable social security system are the most powerful determinants of fertility. The studies indicate that fertility declines are induced by models of development that stress widespread social progress rather than provision of contraceptives and associated services. Examination of the Chinese demographic experience suggests that it falls into 5 clearly identifiable stages, beginning with high mortality and even higher fertility until 1957, the Great Leap Forward and its aftermath, the demographic transition from 1969 to 1979, and the stage of renewed growth from 1980 to the present. China has followed 3 radically different development models since 1957. Its experience demonstrates that development policies that result directly in generalized improvements in social conditions in areas such as nutrition, education, employment, and social security are the fundamental determinants of fertility decline. Chinese experience also suggests that when development policies are modified to stress national economic growth at the expense of social improvements, the need for children is also stimulated.

  7. Reducing rice field algae and cyanobacteria abundance by altering phosphorus fertilizer applications

    USDA-ARS?s Scientific Manuscript database

    In California’s water seeded rice systems algal/cyanobacterial biomass can be a problem during rice establishment. Algal/cyanobacterial growth may be stimulated by phosphorus (P) additions in freshwater habitats, so we set up experiments to evaluate the effects of fertilizer P management on algal/cy...

  8. Long-term effects of GnRH agonists on fertility and behaviour.

    PubMed

    Goericke-Pesch, S

    2017-04-01

    This review aimed to summarize the present knowledge about the effects of GnRH agonist slow-release implants (GnRH A-SRI) on fertility and behaviour in male and female dogs and cats with special focus on deslorelin. Following an initial stimulation of gonadotropin and testosterone secretion possibly associated with an improved semen quality, GnRH A-SRI induce long-term depression of fertility in male dogs and cats with, however, a large individual variation in onset and duration of efficacy especially in cats. The GnRH A-SRI furthermore interfere with testosterone-dependent/affected behaviour; a significant positive effect in reducing sexual behaviour and libido, hypersexuality, intermale dominance and excessive territorial urine marking has been described. Rates of improvement of the respective behaviour are comparable to those after surgical castration, making GnRH A-SRI a valuable option to predict castration-related effects on behaviour and to identify animals where surgical castration will not be beneficial. No effect has been seen in reducing aggression towards humans indicating the need for behavioural therapy to control this problem. Effects on spermatogenesis, steroidogenesis and behaviour have by now been shown to be fully reversible. Knowledge in females is more limited, and particularly, the initial induction of a possibly fertile oestrus and individual variation in duration of efficacy remain problems in bitches and queens treated for suppression of fertility. However, long-term suppression of oestrous cycle and fertility seems to be possible with induced effects shown to be reversible including restoration of normal fertility after the end of efficacy/GNRH A-SRI removal. © 2016 Blackwell Verlag GmbH.

  9. Simple prostatectomy

    MedlinePlus

    ... if you have: Problems emptying your bladder (urinary retention) Frequent urinary tract infections Frequent bleeding from the ... to internal organs Erection problems (impotence) Loss of sperm fertility ( infertility ) Passing semen back up into the ...

  10. Fertility, Pregnancy, and Lactation in Rheumatoid Arthritis.

    PubMed

    de Jong, Pascal H P; Dolhain, Radboud J E M

    2017-05-01

    Fertility is impaired in women with rheumatoid arthritis (RA), whereas less is known about male fertility problems. Pregnancy outcome in patients with RA is slightly less favorable compared with the general population, especially in patients with active disease. Disease activity usually improves during pregnancy, but less than previously thought. Although several antirheumatic drugs are contraindicated in pregnancy, more treatment options are available. There is evidence on the safety of TNF inhibitors in pregnancy. Given the impact of active disease on fertility and pregnancy outcome, a treat-to-target strategy is recommended for patients who are pregnant or have a wish to conceive. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Quantifying Cradle-to-Farm Gate Life-Cycle Impacts Associated with Fertilizer used for Corn, Soybean, and Stover Production

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Powers, S. E.

    2005-05-01

    Fertilizer use can cause environmental problems, particular eutrophication of water bodies from excess nitrogen or phosphorus. Increased fertilizer runoff is a concern for harvesting corn stover for ethanol production. This modeling study found that eutrophication potential for the base case already exceeds proposed water quality standards, that switching to no-till cultivation and collecting stover increased that eutrophication potential by 21%, and that switching to continuous-corn production on top of that would triple eutrophication potential.

  12. Study on the quantitative relationship between Agricultural water and fertilization process and non-point source pollution based on field experiments

    NASA Astrophysics Data System (ADS)

    Wang, H.; Chen, K.; Wu, Z.; Guan, X.

    2017-12-01

    In recent years, with the prominent of water environment problem and the relative increase of point source pollution governance, especially the agricultural non-point source pollution problem caused by the extensive use of fertilizers and pesticides has become increasingly aroused people's concern and attention. In order to reveal the quantitative relationship between agriculture water and fertilizer and non-point source pollution, on the basis of elm field experiment and combined with agricultural drainage irrigation model, the agricultural irrigation water and the relationship between fertilizer and fertilization scheme and non-point source pollution were analyzed and calculated by field emission intensity index. The results show that the variation of displacement varies greatly under different irrigation conditions. When the irrigation water increased from 22cm to 42cm, the irrigation water increased by 20 cm while the field displacement increased by 11.92 cm, about 66.22% of the added value of irrigation water. Then the irrigation water increased from 42 to 68, irrigation water increased 26 cm, and the field displacement increased by 22.48 cm, accounting for 86.46% of irrigation water. So there is an "inflection point" between the irrigation water amount and field displacement amount. The load intensity increases with the increase of irrigation water and shows a significant power correlation. Under the different irrigation condition, the increase amplitude of load intensity with the increase of irrigation water is different. When the irrigation water is smaller, the load intensity increase relatively less, and when the irrigation water increased to about 42 cm, the load intensity will increase considerably. In addition, there was a positive correlation between the fertilization and load intensity. The load intensity had obvious difference in different fertilization modes even with same fertilization level, in which the fertilizer field unit load intensity increased the most in July. The results provide some basis for the field control and management of agricultural non-point source pollution.

  13. HINDU-MUSLIM FERTILITY DIFFERENTIAL IN INDIA: A COHORT APPROACH.

    PubMed

    Pasupuleti, Samba Siva Rao; Pathak, Prasanta; Jatrana, Santosh

    2017-03-01

    Hindus and Muslims together account for 94% of the population of India. The fertility differential between these two religious groups is a sensitive and hotly debated issue in political and academic circles. However, the debate is mostly based on a period approach to fertility change, and there have been some problems with the reliability of period fertility data. This study investigated cohort fertility patterns among Hindus and Muslims and the causes of the relatively higher level of fertility among Muslims. Data from the three National Family Health Surveys conducted in India since the early 1990s were analysed using a six-parameter special form of the Gompertz model and multiple linear regression models. The results show a gap of more than 1.3 children per woman between those Muslim and Hindu women who ended/will end their reproductive period in the calendar years 1993 to 2025. The socioeconomic and demographic characteristics of Muslims explain 31.2% of the gap in fertility between Muslims and Hindus, while the desire for more children among Muslims explains an additional 18.2% of the gap in fertility.

  14. Did fertility go up after the Oklahoma City bombing? An analysis of births in metropolitan counties in Oklahoma, 1990-1999.

    PubMed

    Rodgers, Joseph Lee; St John, Craig A; Coleman, Ronnie

    2005-11-01

    Political and sociocultural events (e.g., Brown v. Board of Education in 1954 and the German reunification in 1989) and natural disasters (e.g., Hurricane Hugo in 1989) can affect fertility. In our research, we addressed the question of whether the Oklahoma City bombing in April 1995, a man-made disaster, influenced fertility patterns in Oklahoma. We defined three theoretical orientations--replacement theory, community influence theory, and terror management theory--that motivate a general expectation of birth increases, with different predictions emerging from time and geographic considerations. We used two different empirical methodologies. First, we fitted dummy-variable regression models to monthly birth data from 1990 to 1999 in metropolitan counties. We used birth counts to frame the problem and general fertility rates to address the problem formally. These analyses were organized within two design structures: a control-group interrupted time-series design and a difference-in-differences design. In these analyses, Oklahoma County showed an interpretable, consistent, and significant increase in births. Second, we used graphical smoothing models to display these effects visually. In combination, these methods provide compelling support for a fertility response to the Oklahoma City bombing. Certain parts of each theory helped us organize and understand the pattern of results.

  15. PubMed Central

    Lambert, R. D.

    1983-01-01

    In vitro fertilization of human oocytes is successful only when several techniques are perfectly mastered. Accurate prediction of imminent ovulation by rapid radioimmunoassay of luteinizing hormone in the plasma, suitable hormonal treatment or ultrasonography, or a combination of these, leads to the recovery of mature oocytes. Factors such as suction strength and bore size of the aspiration needle may interfere with the recovery of follicular oocytes during endoscopy. Capacitation of the spermatozoa, the most critical part of the whole process, requires the presence of serum or serum albumin. Fertilization and embryonic development in vitro occur in well defined experimental conditions. However, in spite of all the precautions currently taken, the rate of success, in terms of pregnancies continued to term, is still much lower than that observed under natural conditions. Much better results will likely be obtained in the near future. The literature suggests that in vitro fertilization and embryo transfer do not have any harmful physical effects on the offspring. Moreover, the laws of biology suggest that in vitro fertilization of human oocytes does not raise any ethical problem with regard to the potential offspring. However, it is extremely difficult to identify ethical problems related to the influence of the technique of in vitro fertilization on the evolution of man and human society. Images FIG. 1 PMID:6339019

  16. Therapy and Counseling

    MedlinePlus

    ... infidelity, divorce, or other relationship issues sexual problems stress and anxiety addictions and compulsions grief, loss, or bereavement anger career choice parenting or family problems phobias insomnia fertility issues chronic pain or illness domestic violence ...

  17. Pursuing conception: a physician's experience with in-vitro fertilization.

    PubMed Central

    McCall, M

    1996-01-01

    Infertility is a common problem. Approximately one in seven North American couples will experience it, either by being unable to conceive after a year of trying or by experiencing recurrent miscarriages. A family physician outlines her experiences when being treated for infertility by in-vitro fertilization and embryo transfer. PMID:8625028

  18. Partnered Decisions? U.S. Couples and Medical Help-Seeking for Infertility

    ERIC Educational Resources Information Center

    Johnson, Katherine M.; Johnson, David R.

    2009-01-01

    We examined male partners' influence on the decision to seek medical help for infertility using the National Study of Fertility Barriers. Building upon an existing help-seeking framework, we incorporated characteristics of both partners from 219 heterosexual couples who had ever perceived a fertility problem. In logistic regression analyses, we…

  19. Uterine Fibroid Embolisation – Potential Impact on Fertility and Pregnancy Outcome

    PubMed Central

    David, M.; Kröncke, T.

    2013-01-01

    The current standard therapy to treat myomas in women wishing to have children consists of minimally invasive surgical myomectomy. Uterine artery embolisation (UAE) has also been discussed as another minimally invasive treatment option to treat myomas. This review evaluates the literature of the past 10 years on fibroid embolisation and its impact on fertility and pregnancy. Potential problems associated with UAE such as radiation exposure of the ovaries, impairment of ovarian function and the impact on pregnancy and child birth are discussed in detail. Previously published reports of at least 337 pregnancies after UAE were evaluated. The review concludes that UAE to treat myomas can only be recommended in women with fertility problems due to myomas who refuse surgery or women with an unacceptably high surgical risk, because the evaluated case reports and studies show that UAE significantly increases the risk of spontaneous abortion; there is also evidence of pathologically increased levels for other obstetric outcome parameters. There are still very few prospective studies which provide sufficient evidence for a definitive statement on the impact of UAE therapy on fertility rates and pregnancy outcomes. PMID:26633901

  20. In Vitro Measures for Assessing Boar Semen Fertility.

    PubMed

    Jung, M; Rüdiger, K; Schulze, M

    2015-07-01

    Optimization of artificial insemination (AI) for pig production and evaluation of the fertilizing capacity of boar semen are highly related. Field studies have demonstrated significant variation in semen quality and fertility. The semen quality of boars is primarily affected by breed and season. AI centres routinely examine boar semen to predict male fertility. Overall, the evaluation of classical parameters, such as sperm morphology, sperm motility, sperm concentration and ejaculate volume, allows the identification of ejaculates corresponding to poor fertility but not high-efficiency prediction of field fertility. The development of new sperm tests for measuring certain sperm functions has attempted to solve this problem. Fluorescence staining can categorize live and dead spermatozoa in the ejaculate and identify spermatozoa with active mitochondria. Computer-assisted semen analysis (CASA) provides an objective assessment of multiple kinetic sperm parameters. However, sperm tests usually assess only single factors involved in the fertilization process. Thus, basing prediction of fertilizing capacity on a selective collection of sperm tests leads to greater accuracy than using single tests. In the present brief review, recent diagnostic laboratory methods that directly relate to AI performance as well as the development of a new boar fertility in vitro index are discussed. © 2015 Blackwell Verlag GmbH.

  1. Associations of insulin resistance later in lactation on fertility of dairy cows.

    PubMed

    Baruselli, P S; Vieira, L M; Sá Filho, M F; Mingoti, R D; Ferreira, R M; Chiaratti, M R; Oliveira, L H; Sales, J N; Sartori, R

    2016-07-01

    The challenge of getting dairy cows pregnant during early lactation is a well-described, worldwide problem. However, specifically in farms with poor reproductive, nutritional, and environmental conditions/management, a low pregnancy rate during early lactation is followed inevitably by an increased number of nonpregnant cows after 150 days in milk, with even more difficulties to achieve pregnancy. Therefore, several studies were designed to understand and develop strategies to mitigate reduced fertility of cows during late lactation. Experiments were performed under tropical regions to determine metabolic status during lactation and association of stage of lactation on oocyte quality and fertility. Lactating cows with extended days not pregnant (e.g.,>150 days in milk) often had systemic metabolic alterations, including development of peripheral insulin resistance and various oocyte alterations, including reduced expression of genes encoding glucose transport proteins, reduced amounts of mtDNA, increased expression of mitochondria-related genes, and increased expression of apoptosis-related genes. Additionally, in vitro embryo production and pregnancy per AI were lower in late- versus early-lactation cows in some but not all studies. Notwithstanding, when a normal embryo was transferred to a cow in late lactation, the pregnancy per transfer was reasonable, reinforcing the assertion that fertility problems in late-lactation cows may be associated with oocyte quality, fertilization, and/or failure of early embryo development. In conclusion, insulin resistance may reduce oocyte competence and consequently fertility in late-lactation dairy cows. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. Obesity: modern man's fertility nemesis.

    PubMed

    Cabler, Stephanie; Agarwal, Ashok; Flint, Margot; du Plessis, Stefan S

    2010-07-01

    The obesity pandemic has grown to concerning proportions in recent years, not only in the Western World, but in developing countries as well. The corresponding decrease in male fertility and fecundity may be explained in parallel to obesity, and obesity should be considered as an etiology of male fertility. Studies show that obesity contributes to infertility by reducing semen quality, changing sperm proteomes, contributing to erectile dysfunction, and inducing other physical problems related to obesity. Mechanisms for explaining the effect of obesity on male infertility include abnormal reproductive hormone levels, an increased release of adipose-derived hormones and adipokines associated with obesity, and other physical problems including sleep apnea and increased scrotal temperatures. Recently, genetic factors and markers for an obesity-related infertility have been discovered and may explain the difference between fertile obese and infertile obese men. Treatments are available for not only infertility related to obesity, but also as a treatment for the other comorbidities arising from obesity. Natural weight loss, as well as bariatric surgery are options for obese patients and have shown promising results in restoring fertility and normal hormonal profiles. Therapeutic interventions including aromatase inhibitors, exogenous testosterone replacement therapy and maintenance and regulation of adipose-derived hormones, particularly leptin, may also be able to restore fertility in obese males. Because of the relative unawareness and lack of research in this area, controlled studies should be undertaken and more focus should be given to obesity as an etiolgy of male infertility.

  3. Farmers' perceptions of land degradation and their investments in land management: a case study in the Central Rift Valley of Ethiopia.

    PubMed

    Adimassu, Zenebe; Kessler, Aad; Yirga, Chilot; Stroosnijder, Leo

    2013-05-01

    To combat land degradation in the Central Rift Valley (CRV) of Ethiopia, farmers are of crucial importance. If farmers perceive land degradation as a problem, the chance that they invest in land management measures will be enhanced. This study presents farmers' perceptions of land degradation and their investments in land management, and to what extent the latter are influenced by these perceptions. Water erosion and fertility depletion are taken as main indicators of land degradation, and the results show that farmers perceive an increase in both indicators over the last decade. They are aware of it and consider it as a problem. Nevertheless, farmers' investments to control water erosion and soil fertility depletion are very limited in the CRV. Results also show that farmers' awareness of both water erosion and soil fertility decline as a problem is not significantly associated with their investments in land management. Hence, even farmers who perceive land degradation on their fields and are concerned about its increase over the last decade do not significantly invest more in water erosion and soil fertility control measures than farmers who do not perceive these phenomena. Further research is needed to assess which other factors might influence farmers' investments in land management, especially factors related to socioeconomic characteristics of farm households and plot characteristics which were not addressed by this study.

  4. Genetic relationships among body condition score, body weight, milk yield, and fertility in dairy cows.

    PubMed

    Berry, D P; Buckley, F; Dillon, P; Evans, R D; Rath, M; Veerkamp, R F

    2003-06-01

    Genetic (co)variances between body condition score (BCS), body weight (BW), milk production, and fertility-related traits were estimated. The data analyzed included 8591 multiparous Holstein-Friesian cows with records for BCS, BW, milk production, and/or fertility from 78 seasonal calving grass-based farms throughout southern Ireland. Of the cows included in the analysis, 4402 had repeated records across the 2 yr of the study. Genetic correlations between level of BCS at different stages of lactation and total lactation milk production were negative (-0.51 to -0.14). Genetic correlations between BW at different stages of lactation and total lactation milk production were all close to zero but became positive (0.01 to 0.39) after adjusting BW for differences in BCS. Body condition score at different stages of lactation correlated favorably with improved fertility; genetic correlations between BCS and pregnant 63 d after the start of breeding season ranged from 0.29 to 0.42. Both BW at different stages of lactation and milk production tended to exhibit negative genetic correlations with pregnant to first service and pregnant 63 d after the start of the breeding season and positive genetic correlations with number of services and the interval from first service to conception. Selection indexes investigated illustrate the possibility of continued selection for increased milk production without any deleterious effects on fertility or average BCS, albeit, genetic merit for milk production would increase at a slower rate.

  5. Clinical guide to fertility preservation in hematopoietic cell transplant recipients

    PubMed Central

    Joshi, S; Savani, BN; Chow, EJ; Gilleece, MH; Halter, J; Jacobsohn, DA; Pidala, J; Quinn, GP; Cahn, J-Y; Jakubowski, AA; Kamani, NR; Lazarus, HM; Rizzo, JD; Schouten, HC; Socie, G; Stratton, P; Sorror, ML; Warwick, AB; Wingard, JR; Loren, AW; Majhail, NS

    2014-01-01

    With broadening indications, more options for hematopoietic cell transplantation (HCT) and improvement in survival, the number of long-term HCT survivors is expected to increase steadily. Infertility is a frequent problem that long-term HCT survivors and their partners face and it can negatively impact on the quality of life. The most optimal time to address fertility issues is before the onset of therapy for the underlying disease; however, fertility preservation should also be addressed before HCT in all children and patients of reproductive age, with referral to a reproductive specialist for patients interested in fertility preservation. In vitro fertilization (IVF) and embryo cryopreservation, oocyte cryopreservation and ovarian tissue banking are acceptable methods for fertility preservation in adult women/pubertal females. Sperm banking is the preferred method for adult men/pubertal males. Frequent barriers to fertility preservation in HCT recipients may include the perception of lack of time to preserve fertility given an urgency to move ahead with transplant, lack of patient–physician discussion because of several factors (for example, time constraints, lack of knowledge), inadequate access to reproductive specialists, and costs and lack of insurance coverage for fertility preservation. There is a need to raise awareness in the medical community about fertility preservation in HCT recipients. PMID:24419521

  6. Soil problems in China and its lessons for other developing countries

    NASA Astrophysics Data System (ADS)

    Chen, N.; Widjajanto, D. W.; Zheng, Y.

    2018-01-01

    With the rapid growth of economy in China for more than 35 years since 1980, the soils in China experienced severe chances featured in high input of chemical fertilizers indeed of organic fertilizers to pursue high yield for the ever-growing population and the increase of life style and in high input of a large amount of metals especially cadmium from manure and atmospheric deposition. The shift of fertilizer application pattern and the high-yield output greatly change the soil quality, of which soil acidification is one of the main problems. Soil acidification and high cadmium input not only caused pollution on the soil but also contaminated the food. Cadmium with high percentage based on the strict soil quality standard (cadmium 0.3 mg/kg for soil, 0.2 mg/kg for rice grain). This paper will elucidate the soil pollution process in China during this 35 years and evaluate the soil and food problem properly and it may give a lesson for other developing countries when they are pave the way of modernization.

  7. The Quality of Life in Pregnant Women Conceiving Through in Vitro Fertilization.

    PubMed

    Globevnik Velikonja, Vislava; Lozej, Tina; Leban, Gaja; Verdenik, Ivan; Vrtačnik Bokal, Eda

    2016-03-01

    The aim was to determine whether pregnant women conceiving through in vitro fertilization (IVF) differ from those conceiving spontaneously in terms of psychological well-being and the quality of life. In a prospective study we included 75 women conceived after IVF and 78 who conceived spontaneously in the same time period (control group). All the women were sent a self-report questionnaire about demographic and reproductive history, health, pregnancy concerns, containing Subjective Quality of Life Scale (QLS), Positive and Negative Affect Schedule (PANAS), the Psychological Well-Being Scale (PWB), Beck Depression Inventory (BDI), and Zung Self-Assessment Anxiety Scale (SAS); obstetric and newborn's data were obtained from medical records. Response rate was 66.6% in the IVF and 83.3% in control group. The mean women's age was 33.8 years in the IVF, and 32.5 years in the control group (NS). There were no significant differences between groups on the most of the outcome measures assessing psychological status. IVF mothers were just less satisfied in "friend/acquaintances" (P=0.03), a higher percentage had sexual problems prior to conception (P=0.03); the length of hospitalization during pregnancy was longer (P=0.02), and the preterm delivery rate was higher (P=0.01). Withingroup changes over gestation time indicated that IVF women, not controls, showed an increase in positive affect (P=0.04) and purpose in life (P=0.05). IVF women are inclined to social isolation. Despite more medical problems during pregnancy, they reported improved positive emotions and purpose in life as the pregnancy progressed.

  8. The Quality of Life in Pregnant Women Conceiving Through in Vitro Fertilization

    PubMed Central

    GLOBEVNIK VELIKONJA, Vislava; LOZEJ, Tina; LEBAN, Gaja; VERDENIK, Ivan; VRTAČNIK BOKAL, Eda

    2016-01-01

    Objective The aim was to determine whether pregnant women conceiving through in vitro fertilization (IVF) differ from those conceiving spontaneously in terms of psychological well-being and the quality of life. Methods In a prospective study we included 75 women conceived after IVF and 78 who conceived spontaneously in the same time period (control group). All the women were sent a self-report questionnaire about demographic and reproductive history, health, pregnancy concerns, containing Subjective Quality of Life Scale (QLS), Positive and Negative Affect Schedule (PANAS), the Psychological Well-Being Scale (PWB), Beck Depression Inventory (BDI), and Zung Self-Assessment Anxiety Scale (SAS); obstetric and newborn’s data were obtained from medical records. Response rate was 66.6% in the IVF and 83.3% in control group. Results The mean women’s age was 33.8 years in the IVF, and 32.5 years in the control group (NS). There were no significant differences between groups on the most of the outcome measures assessing psychological status. IVF mothers were just less satisfied in “friend/acquaintances” (P=0.03), a higher percentage had sexual problems prior to conception (P=0.03); the length of hospitalization during pregnancy was longer (P=0.02), and the preterm delivery rate was higher (P=0.01). Withingroup changes over gestation time indicated that IVF women, not controls, showed an increase in positive affect (P=0.04) and purpose in life (P=0.05). Conclusions IVF women are inclined to social isolation. Despite more medical problems during pregnancy, they reported improved positive emotions and purpose in life as the pregnancy progressed. PMID:27647083

  9. The Population Problem as Economic Disarticulation.

    ERIC Educational Resources Information Center

    Yapa, Lakshman S.

    1985-01-01

    Overpopulation exists when people lack the basic means of subsistence, or when there is massive and permanent unemployment. Population problems of developing countries are examined, and causes of high rates of fertility are discussed. The utilization of productive resources in solving population problems is also examined. (RM)

  10. Fertility counseling and preservation practices in youth with lupus and vasculitis undergoing gonadotoxic therapy.

    PubMed

    Nahata, Leena; Sivaraman, Vidya; Quinn, Gwendolyn P

    2016-11-01

    To assess fertility counseling and preservation practices among children, adolescents, and young adults with rheumatic diseases undergoing cyclophosphamide (CTX) treatment. Retrospective chart review (2006-2016). Academic pediatric center. Male and female patients with systemic lupus erythematosus, Wegener's granulomatosis/granulomatosis with polyangiitis, or other vaculitides, receiving CTX treatment. None. Documentation of fertility counseling and fertility preservation. A total of 58 subjects met the inclusion criteria; 5 were excluded due to incomplete records, thus N = 53. Of these 75% were female (N = 40). Median age was 14 years at diagnosis and 15 years at first CTX treatment. A total of 51% of subjects (69% of males and 45% of females) had no documentation about potential fertility loss before CTX treatment. Among females where fertility counseling was documented, the only fertility preservation option discussed was leuprolide acetate (LA), which was pursued in all of these cases. Of 13 males (77% postpubertal), 3 were offered sperm banking, of whom 2 declined and the other attempted after treatment began and was azoospermic. Of 53 patients, 1 was referred to a fertility specialist. Mean cumulative CTX dose was 9.2 g in males and 8 g in females. Based on these findings, increasing awareness about infertility risk, fertility preservation options, and referral to fertility specialists is needed among pediatric rheumatologists. Prospective studies are needed to assess fertility outcomes in this patient population (including effectiveness of LA with regard to pregnancy rates [PRs]), as well as barriers/facilitators to fertility counseling and fertility preservation. Copyright © 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  11. Development of a health promotion programme to improve awareness of factors that affect fertility, and evaluation of its reach in the first 5 years.

    PubMed

    Hammarberg, Karin; Norman, Robert J; Robertson, Sarah; McLachlan, Robert; Michelmore, Janet; Johnson, Louise

    2017-06-01

    Awareness among people of reproductive age about the factors that influence fertility and reproductive outcomes, including medically assisted reproduction outcomes, is generally low. To improve awareness about the potentially modifiable factors that affect fertility and reproductive outcomes, 'Your Fertility', a fertility health promotion programme funded by the Australian Government, was established in 2011. This paper describes the development and evaluation of the reach of the Your Fertility programme from its inception in 2011 to June 2016. Systematically recorded outcomes for the programme's key focus areas and Google Analytics data were collated. Key achievements include developing and maintaining an internationally renowned website that experiences high growth and demand for fertility-related information; by 2016, over 5 million users had viewed more than 10 million webpages, and over 96,000 users had engaged in programme messages across social media. Programme messages have reached more than 4 million Australian social media users, and a potential audience of 150 million through media coverage across more than 320 media features. More than 4200 education and health professionals have completed online learning modules, and external partnerships have been established with 14 separate organizations. Data collected over 5 years indicate that the Your Fertility programme meets a need for targeted, evidence-based, accessible fertility-related information.

  12. [Effects of different fertilization regimes on weed communities in wheat fields under rice-wheat cropping system].

    PubMed

    Yuan, Fang; Li, Yong; Li, Fen-hua; Sun, Guo-jun; Han, Min; Zhang, Hai-yan; Ji, Zhong; Wu, Chen-yu

    2016-01-01

    To reveal the effects of different fertilization regimes on weed communities in wheat fields under a rice-wheat rotation system, a survey was conducted before wheat harvest in 2014 after a 4-year long-term recurrent fertilization scheme. Weed species types, density, height and diversity index under different fertilization and straw-returning schemes in wheat fields were studied and complemented with a canonical correspondence analysis on weed community distribution and soil nutrient factors. Twenty weed species were recorded among 36 wheat fields belonging to 19 genera and 11 families. Beckmannia syzigachne, Hemistepta lyrata, Malachium aquaticum and Cnidium monnieri were widely distributed throughout the sampled area. Long-term fertilization appeared to reduce weed species richness and density, particularly for broadleaf weeds, but increased weed height. Diversity and evenness indices of weed communities were lower and dominance indices were higher in fields where chemical fertilizers were applied alone or combined with organic fertilizers, especially, where organic-inorganic compound fertilizer was used, in which it readily caused the outbreak of a dominant species and severe damage. Conversely, diversity and evenness indices of weed communities were higher and dominance indices were lower when the straw was returned to the field combined with chemical or organic fertilizers, in which weed community structures were complex and stable with lower weed density. Under these conditions weeds only caused slight reduction of wheat growth.

  13. [A general review of the discussion at the Beijing International Symposium on Population and Development].

    PubMed

    Ren, Y

    1985-03-29

    A general review of papers and discussions at the Beijing International Symposium on Population and Development held December 10-14, 1984 is presented. Discussions on population and development included China's population change 1949-1982, impacts of economic change on Tianjin's population, the population factor in economic development policy-making, Japanese population and development, recent population development in Hungary, population and economy, comprehensive long-term population development in Russia, fertility rate change factors in China, Shanghai's population change, and population and economic development in Mian County, Shaanxi Province. Fertility rate changes were discussed, including multinational borderline value assumptions, recent trends in life span fertility rate in China, fertility rate in Jiangsu Province, fertility rate change in Zhejiang Province, and sterilization in Yangjiaping, Thailand. Population and employment discussions included the economic impact of world population change, the 1984 International Population Conference, changes in economically productive population and employment strategy, employed/unemployed populations in Guangdong Province, and the economic composition of China's population. Urbanization discussions covered population and development methodological problems, population growth and economic development in the Pacific region, surplus rural population transfer and economic development in China, urbanization analysis, trends and urban population distribution problems, and Laioning Province population development. Issues in migration, population distribution, and regional population included migration and development of the Great Northwest, internal migration to Beijing, Chinese population growth and economic development by major region, and current population changes of Chinese Tibetans. Under social problems of population, discussions included women's status, development and population change, Shanghai's aging trend, analysis of the aged population, analysis of educational quality in Anhui Province, and the retirement system in Chinese villages.

  14. Why do patients discontinue fertility treatment? A systematic review of reasons and predictors of discontinuation in fertility treatment.

    PubMed

    Gameiro, S; Boivin, J; Peronace, L; Verhaak, C M

    2012-01-01

    BACKGROUND Chances of achieving parenthood are high for couples who undergo fertility treatment. However, many choose to discontinue before conceiving. A systematic review was conducted to investigate patients' stated reasons for and predictors of discontinuation at five fertility treatment stages. METHODS Six databases were systematically searched. Search-terms referred to fertility treatment and discontinuation. Studies reporting on patients' stated reasons for or predictors of treatment discontinuation were included. A list of all reasons for discontinuation presented in each study was made, different categories of reasons were defined and the percentage of selections of each category was calculated. For each predictor, it was noted how many studies investigated it and how many found a positive and/or negative association with discontinuation. RESULTS The review included 22 studies that sampled 21 453 patients from eight countries. The most selected reasons for discontinuation were: postponement of treatment (39.18%, postponement of treatment or unknown 19.17%), physical and psychological burden (19.07%, psychological burden 14%, physical burden 6.32%), relational and personal problems (16.67%, personal reasons 9.27%, relational problems 8.83%), treatment rejection (13.23%) and organizational (11.68%) and clinic (7.71%) problems. Some reasons were common across stages (e.g. psychological burden). Others were stage-specific (e.g. treatment rejection during workup). None of the predictors reported were consistently associated with discontinuation. CONCLUSIONS Much longitudinal and theory led research is required to explain discontinuation. Meanwhile, treatment burden should be addressed by better care organization and support for patients. Patients should be well informed, have the opportunity to discuss values and worries about treatment and receive advice to decide about continuing treatment.

  15. Why do patients discontinue fertility treatment? A systematic review of reasons and predictors of discontinuation in fertility treatment

    PubMed Central

    Gameiro, S.; Boivin, J.; Peronace, L.; Verhaak, C.M.

    2012-01-01

    BACKGROUND Chances of achieving parenthood are high for couples who undergo fertility treatment. However, many choose to discontinue before conceiving. A systematic review was conducted to investigate patients' stated reasons for and predictors of discontinuation at five fertility treatment stages. METHODS Six databases were systematically searched. Search-terms referred to fertility treatment and discontinuation. Studies reporting on patients' stated reasons for or predictors of treatment discontinuation were included. A list of all reasons for discontinuation presented in each study was made, different categories of reasons were defined and the percentage of selections of each category was calculated. For each predictor, it was noted how many studies investigated it and how many found a positive and/or negative association with discontinuation. RESULTS The review included 22 studies that sampled 21 453 patients from eight countries. The most selected reasons for discontinuation were: postponement of treatment (39.18%, postponement of treatment or unknown 19.17%), physical and psychological burden (19.07%, psychological burden 14%, physical burden 6.32%), relational and personal problems (16.67%, personal reasons 9.27%, relational problems 8.83%), treatment rejection (13.23%) and organizational (11.68%) and clinic (7.71%) problems. Some reasons were common across stages (e.g. psychological burden). Others were stage-specific (e.g. treatment rejection during workup). None of the predictors reported were consistently associated with discontinuation. CONCLUSIONS Much longitudinal and theory led research is required to explain discontinuation. Meanwhile, treatment burden should be addressed by better care organization and support for patients. Patients should be well informed, have the opportunity to discuss values and worries about treatment and receive advice to decide about continuing treatment. PMID:22869759

  16. Advances in development reverse fertility declines.

    PubMed

    Myrskylä, Mikko; Kohler, Hans-Peter; Billari, Francesco C

    2009-08-06

    During the twentieth century, the global population has gone through unprecedented increases in economic and social development that coincided with substantial declines in human fertility and population growth rates. The negative association of fertility with economic and social development has therefore become one of the most solidly established and generally accepted empirical regularities in the social sciences. As a result of this close connection between development and fertility decline, more than half of the global population now lives in regions with below-replacement fertility (less than 2.1 children per woman). In many highly developed countries, the trend towards low fertility has also been deemed irreversible. Rapid population ageing, and in some cases the prospect of significant population decline, have therefore become a central socioeconomic concern and policy challenge. Here we show, using new cross-sectional and longitudinal analyses of the total fertility rate and the human development index (HDI), a fundamental change in the well-established negative relationship between fertility and development as the global population entered the twenty-first century. Although development continues to promote fertility decline at low and medium HDI levels, our analyses show that at advanced HDI levels, further development can reverse the declining trend in fertility. The previously negative development-fertility relationship has become J-shaped, with the HDI being positively associated with fertility among highly developed countries. This reversal of fertility decline as a result of continued economic and social development has the potential to slow the rates of population ageing, thereby ameliorating the social and economic problems that have been associated with the emergence and persistence of very low fertility.

  17. Telescience testbed experiments for biomedical studies: fertilization potential recording of amphibian eggs using tele-manipulation under stereoscopic vision.

    PubMed

    Watanabe, S; Tanaka, M; Wada, Y; Suzuki, H; Takagi, S; Mori, S; Fukai, K; Kanazawa, Y; Takagi, M; Hirakawa, K; Ogasawara, K; Tsumura, K; Ogawa, K; Matsumoto, K; Nagaoka, S; Suzuki, T; Shimura, D; Yamashita, M; Nishio, S

    1994-07-01

    The telescience testbed experiments were carried out to test and investigate the tele-manipulation techniques in the intracellular potential recording of amphibian eggs. Implementation of telescience testbed was set up in the two separated laboratories of the Tsukuba Space center of NASDA, which were connected by tele-communication links. Manipulators respective for a microelectrode and a sample stage of microscope were moved by computers, of which command signals were transmitted from a computer in a remote control room. The computer in the control room was operated by an investigator (PI) who controlled the movement of each manipulator remotely. A stereoscopic vision of the microscope image were prepared by using a head mounted display (HMD) and were indispensable to the intracellular single cell recording. The fertilization potential of amphibian eggs was successfully obtained through the remote operating system.

  18. Fertility transitions and schooling: from micro- to macro-level associations.

    PubMed

    Eloundou-Enyegue, Parfait M; Giroux, Sarah C

    2012-11-01

    Research on the schooling implications of fertility transitions often faces an aggregation problem: despite policy interest in macro-level outcomes, empirical studies usually focus on the micro-level effects of sibsize on schooling. This article proposes an aggregation framework for moving from micro- to macro-level associations between fertility and schooling. The proposed framework is an improvement over previous aggregation methods in that it considers concurrent changes in the effects of sibsize, socioeconomic context, and family structure. The framework is illustrated with data from six sub-Saharan countries. Possible extensions are discussed.

  19. Intentions and attitudes towards parenthood and fertility awareness among Chinese university students in Hong Kong: a comparison with Western samples.

    PubMed

    Chan, C H Y; Chan, T H Y; Peterson, B D; Lampic, C; Tam, M Y J

    2015-02-01

    What are the levels of awareness regarding female fertility and the intentions and attitudes towards parenthood among Chinese university students in Hong Kong compared with their counterparts in the West? Chinese university students in Hong Kong were similarly over-optimistic about the age-related fertility decline, although they were less inclined to have children and undergo fertility treatment compared with their Western counterparts. Past studies of highly educated young adults in Europe and the USA have found that they are not sufficiently aware of the age-related decline in female fertility, and falsely believe that advanced reproductive treatments such as IVF will overcome fertility problems associated with age. Little is known about the perceptions of Chinese students in Hong Kong, a modernized Chinese city where the fertility rate is among the lowest in the world. An online cross-sectional survey of Chinese university students in Hong Kong was conducted in 2013. Results were compared with two similar studies in Sweden and the USA. A total of 367 university students in Hong Kong (275 female, 92 male; mean age 23) responded to an e-mail invitation to participate in an online survey. Intentions and attitudes towards parenthood and awareness regarding female fertility were assessed using the Swedish Fertility Awareness Questionnaire. Like their Western counterparts, a large proportion of Chinese university students underestimated the age-related fertility decline (92%) and overestimated the fertility treatment success rate (66%). However, they were less inclined to have children, were more aware of and less concerned with infertility and were less motivated to seek solutions in the event of a fertility problem. These comparisons were significant at P < 0.05. Self-selection bias was inevitable in the questionnaire survey, and the anonymous nature of the survey did not permit the collection of characteristics of non-responders. International comparisons warrant caution because the Hong Kong sample was older than the US sample (mean age 20), but not older than the Sweden sample (mean age 24). While this study was consistent with past Western studies on the lack of fertility awareness among highly educated young people, the findings reveal significant cultural differences in family planning and responses to infertility between Asia and the West. © The Author 2014. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  20. Extended Axiomatic Conjoint Measurement: A Solution to a Methodological Problem in Studying Fertility-Related Behaviors.

    ERIC Educational Resources Information Center

    Nickerson, Carol A.; McClelland, Gary H.

    1988-01-01

    A methodology is developed based on axiomatic conjoint measurement to accompany a fertility decision-making model. The usefulness of the model is then demonstrated via an application to a study of contraceptive choice (N=100 male and female family-planning clinic clients). Finally, the validity of the model is evaluated. (TJH)

  1. Substantiation of the Parameters of the Central Distributor for Mineral Fertilizers

    ERIC Educational Resources Information Center

    Nukeshev, Sayakhat O.; Eskhozhin, Kairat D.; Tokushev, Masgut H.; Zhazykbayeva, Zhazira M.

    2016-01-01

    The main problem of distribution systems with a centralized metering seed actions of pneumatic planters is deficient feed-rate consistency of seeds in supply coulters. Thus, the purpose of the study is to develop the optimal ways of decreasing the irregular distribution of the seeds and mineral fertilizers in the coulters. In order to achieve this…

  2. Application of different fertilizers on morphological traits of dill (Anethum graveolens L.).

    PubMed

    Nejatzadeh-Barandozi, Fatemeh; Gholami-Borujeni, Fathollah

    2014-12-01

    The aim of this study was to evaluate the effects of nitroxin biofertilizer and chemical fertilizer on the growth, yield, and essential oil composition of dill. The experiment was conducted under field condition in randomized complete block design with three replications and two factors. The first factor was the concentrations of nitroxin biofertilizer (0%, 50%, and 100%) of the recommended amount (1 l of biological fertilizer for 30 kg of seed). The second factor was the following chemical fertilizer treatments: no fertilizer (control) and 50 and 100 kg ha(-1) urea along with 300 kg ha(-1) ammonium phosphate. Different characteristics such as plant height, number of umbel per plant, number of umbellet per umbel, number of grain per umbellet, 1,000 seed weight, grain yield, biological yield, and oil percentage were recorded. According to the results, the highest height, biological yield, and grain yield components (except harvest index) were obtained on biological fertilizer. The results showed the highest essential oil content detected in biological fertilizer and chemical fertilizer. Identification of essential oil composition showed that the content of carvone increased with the application of biofertilizers and chemical fertilizers. The results indicated that the application of biofertilizers enhanced yield and other plant criteria in this plant. Generally, it seems that the use of biofertilizers or combinations of biofertilizer and chemical fertilizer could improve dill performance in addition to reduction of environmental pollution.

  3. Cancer treatment: fertility and sexual side effects in women

    MedlinePlus

    ... can include: Not being able to have an orgasm Numbness or pain in the genitals Problems with ... desire Pain with sex and problems having an orgasm Vaginal dryness and shrinking and thinning of the ...

  4. Production of organic fertilizer from olive mill wastewater by combining solar greenhouse drying and composting.

    PubMed

    Galliou, F; Markakis, N; Fountoulakis, M S; Nikolaidis, N; Manios, T

    2018-05-01

    Olive mill wastewater (OMW) is generated during the production of olive oil. Its disposal is still a major environmental problem in Mediterranean countries, despite the fact that a large number of technologies have been proposed up to date. The present work examines for the first time a novel, simple and low-cost technology for OMW treatment combining solar drying and composting. In the first step, OMW was dried in a chamber inside a solar greenhouse using swine manure as a bulking agent. The mean evaporation rate was found to be 5.2 kg H 2 O/m 2 /d for a drying period of 6 months (February-August). High phenol (75%) and low nitrogen (15%) and carbon (15%) losses were recorded at the end of the solar drying process. The final product after solar drying was rich in nutrients (N: 27.8 g/kg, P: 7.3 g/kg, K: 81.6 g/kg) but still contained significant quantities of phenols (18.4 g/kg). In order to detoxify the final product, a composting process was applied as a second step with or without the use of grape marc as bulking agent. Results showed that the use of grape marc as a bulking agent at a volume ratio of 1:1 achieved a higher compost temperature profile (60 °C) than 2:1 (solar drying product: grape marc) or no use (solar drying product). The end product after the combination of solar drying and composting had the characteristics of an organic fertilizer (57% organic carbon) rich in nutrients (3.5% N, 1% P, 6.5% K) with quite low phenol content (2.9 g/kg). Finally, the use of this product for the cultivation of pepper plants approved its fertility which was found similar with commercial NPK fertilizers. Copyright © 2018 Elsevier Ltd. All rights reserved.

  5. Fertility and Pregnancy Outcome After Abdominal Irradiation That Included or Excluded the Pelvis in Childhood Tumor Survivors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sudour, Helene, E-mail: h.sudour@hotmail.f; Chastagner, Pascal; Claude, Line

    Purpose: To evaluate fertility after abdominal and/or pelvic irradiation in long-term female survivors. Methods and Materials: Puberty and pregnancy outcome were analyzed in female survivors of childhood cancer (aged <18 years) treated with abdominal and/or pelvic radiotherapy (RT) at one of two French centers (Nancy and Lyon) between 1975 and 2004. Data were obtained from medical records and questionnaires sent to the women. Results: A total of 84 patients who had received abdominal and/or pelvic RT during childhood and were alive and aged more than 18 years at the time of the study made up the study population. Of themore » 57 female survivors treated with abdominal RT that excluded the pelvis, 52 (91%) progressed normally through puberty and 23 (40%) had at least one recorded pregnancy. Of the 27 patients treated with pelvic RT, only 10 (37%) progressed normally through puberty and 5 (19%) had at least one recorded pregnancy. Twenty-two women (seventeen of whom were treated with pelvic RT) had certain subfertility. A total of 50 births occurred in 28 women, with one baby dying at birth; one miscarriage also occurred. There was a high prevalence of prematurity and low birth weight but not of congenital malformations. Conclusions: Fertility can be preserved in patients who undergo abdominal RT that excludes the pelvis, taking into account the other treatments (e.g., chemotherapy with alkylating agents) are taken into account. When RT includes the pelvis, fertility is frequently impaired and women can have difficulty conceiving. Nevertheless, pregnancies can occur in some of these women. The most important factor that endangers a successful pregnancy after RT is the total dose received by the ovaries and uterus. This radiation dose has to be systematically recorded to improve our ability to follow up patients.« less

  6. Biochemical Disincentives to Fertilizing Cellulosic Ethanol Crops

    NASA Astrophysics Data System (ADS)

    Gallagher, M. E.; Hockaday, W. C.; Snapp, S.; McSwiney, C.; Baldock, J.

    2010-12-01

    Corn grain biofuel crops produce the highest yields when the cropping ecosystem is not nitrogen (N)-limited, achieved by application of fertilizer. There are environmental consequences for excessive fertilizer application to crops, including greenhouse gas emissions, hypoxic “dead zones,” and health problems from N runoff into groundwater. The increase in corn acreage in response to demand for alternative fuels (i.e. ethanol) could exacerbate these problems, and divert food supplies to fuel production. A potential substitute for grain ethanol that could reduce some of these impacts is cellulosic ethanol. Cellulosic ethanol feedstocks include grasses (switchgrass), hardwoods, and crop residues (e.g. corn stover, wheat straw). It has been assumed that these feedstocks will require similar N fertilization rates to grain biofuel crops to maximize yields, but carbohydrate yield versus N application has not previously been monitored. We report the biochemical stocks (carbohydrate, protein, and lignin in Mg ha-1) of a corn ecosystem grown under varying N levels. We measured biochemical yield in Mg ha-1 within the grain, leaf and stem, and reproductive parts of corn plants grown at seven N fertilization rates (0-202 kg N ha-1), to evaluate the quantity and quality of these feedstocks across a N fertilization gradient. The N fertilization rate study was performed at the Kellogg Biological Station-Long Term Ecological Research Site (KBS-LTER) in Michigan. Biochemical stocks were measured using 13C nuclear magnetic resonance spectroscopy (NMR), combined with a molecular mixing model (Baldock et al. 2004). Carbohydrate and lignin are the main biochemicals of interest in ethanol production since carbohydrate is the ethanol feedstock, and lignin hinders the carbohydrate to ethanol conversion process. We show that corn residue carbohydrate yields respond only weakly to N fertilization compared to grain. Grain carbohydrate yields plateau in response to fertilization at moderate levels (67 kg N ha-1). Increasing fertilizer application beyond the point of diminishing returns for grain (67 kg N ha-1) to double the regionally-recommended amount (202 kg N ha-1) resulted in only marginal increases (25%) in crop residue carbohydrate yield, while increasing lignin yields 41%. In the case of at least this ecosystem, high fertilization rates did not result in large carbohydrate yield increases in the crop residue, and instead produced a lower quality feedstock for cellulosic ethanol production.

  7. Fertilizer potential of liquid and solid effluent from thermophilic anaerobic digestion of poultry waste.

    PubMed

    Liedl, B E; Bombardiere, J; Chaffield, J M

    2006-01-01

    Thermophilic anaerobic treatment of poultry litter produces an effluent stream of digested materials that can be separated into solid and liquid fractions for use as a crop fertilizer. The majority of the phosphorus is partitioned into the solid fraction while the majority of the nitrogen is present in the liquid fraction in the form of ammonium. These materials were tested over six years as an alternative fertilizer for the production of vegetable, fruit, and grassland crops. Application of the solids as a field crop fertilizer for vegetables and blueberries resulted in lower yields than the other fertilizer treatments, but an increase in soil phosphorus over a four-year period. Application of the digested liquids on grass and vegetable plots resulted in similar or superior yields to plots treated with commercially available nitrogen fertilizers. Hydroponic production of lettuce using liquid effluent was comparable to a commercial hydroponic fertilizer regime; however, the effluent treatment for hydroponic tomato production required supplementation and conversion of ammonium to nitrate. While not a total fertilizer solution, our research shows the effectiveness of digested effluent as part of a nutrient management program which could turn a livestock residuals problem into a crop nutrient resource.

  8. The development of a phosphite-mediated fertilization and weed control system for rice.

    PubMed

    Manna, Mrinalini; Achary, V Mohan M; Islam, Tahmina; Agrawal, Pawan K; Reddy, Malireddy K

    2016-04-25

    Fertilizers and herbicides are two vital components of modern agriculture. The imminent danger of phosphate reserve depletion and multiple herbicide tolerance casts doubt on agricultural sustainability in the future. Phosphite, a reduced form of phosphorus, has been proposed as an alternative fertilizer and herbicide that would address the above problems to a considerable extent. To assess the suitability of a phosphite-based fertilization and weed control system for rice, we engineered rice plants with a codon-optimized ptxD gene from Pseudomonas stutzeri. Ectopic expression of this gene led to improved root growth, physiology and overall phenotype in addition to normal yield in transgenic plants in the presence of phosphite. Phosphite functioned as a translocative, non-selective, pre- and post-emergent herbicide. Phosphite use as a dual fertilizer and herbicide may mitigate the overuse of phosphorus fertilizers and reduce eutrophication and the development of herbicide resistance, which in turn will improve the sustainability of agriculture.

  9. The development of a phosphite-mediated fertilization and weed control system for rice

    PubMed Central

    Manna, Mrinalini; Achary, V. Mohan M.; Islam, Tahmina; Agrawal, Pawan K.; Reddy, Malireddy K.

    2016-01-01

    Fertilizers and herbicides are two vital components of modern agriculture. The imminent danger of phosphate reserve depletion and multiple herbicide tolerance casts doubt on agricultural sustainability in the future. Phosphite, a reduced form of phosphorus, has been proposed as an alternative fertilizer and herbicide that would address the above problems to a considerable extent. To assess the suitability of a phosphite-based fertilization and weed control system for rice, we engineered rice plants with a codon-optimized ptxD gene from Pseudomonas stutzeri. Ectopic expression of this gene led to improved root growth, physiology and overall phenotype in addition to normal yield in transgenic plants in the presence of phosphite. Phosphite functioned as a translocative, non-selective, pre- and post-emergent herbicide. Phosphite use as a dual fertilizer and herbicide may mitigate the overuse of phosphorus fertilizers and reduce eutrophication and the development of herbicide resistance, which in turn will improve the sustainability of agriculture. PMID:27109389

  10. [Fertility and Environmental Impacts of Urban Scattered Human Feces Used as Organic Granular Fertilizer for Leaf Vegetables].

    PubMed

    Lü, Wen-zhou; Qiao, Yu-xiang; Yu, Ning; Shi, Rong-hua; Wang, Guang-ming

    2015-09-01

    The disposal of urban scattered human feces has become a difficult problem for the management of modern city. In present study, the scattered human feces underwent the collection, scum removal, flocculation and dehydration, finally became the granular fertilizer; the effects of the ratio of fertilizer to soil on the growth of the pakchoi and the quality of soil and leaching water were evaluated, and the feasibility of granular fertilizer manuring the pakchoi was discussed by pot experiments. The results showed that the granular fertilizer significantly enhanced the production of the pakchoi which were not polluted by the intestinal microorganisms under the experiment conditions; meanwhile, at the proper ratio of fertilizer to soil, the concentration of these microorganisms in the leaching water was lower than that in the control check. Chemical analyses of soil revealed that the nutrient content of nitrogen, phosphorus, potassium and organic matters in soil became much richer in all treatments. In addition, the granular fertilizer improved the physical- chemical properties of soil, including raising the level of soil porosity and reducing the volume weight of soil. Application of granular fertilizer won't pollute the soil or leaching water; instead, it can also prevent nitrogen, potassium and intestinal microorganisms from leaching inio ground water at the proper ratio of granular fertilizer to soil.

  11. Reproductive effects of Ficus asperifolia (Moraceae) in female rats.

    PubMed

    Watcho, Pierre; Ngadjui, Esther; Alango, Nkeng-Efouet P; Benoît, Nguelefack T; Kamanyi, Albert

    2009-03-01

    The reproductive effects of Ficus asperifolia in female rats were investigated in the present study. Sperm-positive adult female rats were orally administered (P.O.) either the aqueous and methanol extracts of Ficus asperifolia (100 and 500mg/kg), distilled water (10ml/kg) or 5%Tween 80 (10ml/kg) for seven days. On day 10 of pregnancy, the implantation sites were recorded. In the fertility study, adult female rats received the same test substances for 21 days and, the fertility index and litter size determined. In the uterotrophic test, normal and ovariectomized immature rats were treated for seven days with the dry extract of Ficus asperifolia (100 and 500mg/kg) in the absence and presence of 17ȃ-estradiol benzoate 1µg/animal/day, s.c. On day 8, the uterine growth index was measured. Results of the study showed a significant increase (p<0.05) in the implantation sites and litter size of animals receiving 100mg/kg of the aqueous extract of Ficus asperifolia. In the estrogenic assay, normal immature rats were sensitive to the treatment with Ficus asperifolia than the ovariectomized ones. Our results give added scientific support to the popular use of Ficus asperifolia in the treatment of some cases of women's sterility/infertility related problems.

  12. Chemotherapy-induced damage to ovary: mechanisms and clinical impact.

    PubMed

    Bedoschi, Giuliano; Navarro, Paula Andrea; Oktay, Kutluk

    2016-10-01

    Cancer is a major public health problem around the world. Currently, about 5% of women diagnosed with cancer are of reproductive age. These young survivors may face compromised fertility. The effects of chemotherapeutic agents on ovarian reserve and its clinical consequences are generally inferred from a variety of surrogate markers of ovarian reserve, all aiming to provide prognostic information on fertility or the likelihood of success of infertility treatment. Until recently, the mechanisms that are responsible for chemotherapy-induced ovarian damage were not fully elucidated. The understanding of these mechanisms may lead to targeted treatments to preserve fertility. In this manuscript, we will review the current knowledge on the mechanism of ovarian damage and clinical impact of chemotherapy agents on fertility.

  13. A Classroom Activity Debating the Ethical Issues of Preimplantation Genetic Diagnosis: A Role-Playing Exercise

    ERIC Educational Resources Information Center

    Staddon, William

    2008-01-01

    Almost three decades ago, the birth of Louise Brown in England marked the beginning of the "in vitro" fertilization (IVF) era. IVF is done to overcome infertility problems that some couples experience. Sperm and eggs are collected and fertilized in the lab. ("In vitro" means "in glass" and is used to refer to…

  14. An Evaluation of the Historical Importance of Fertility and Its Reflection in Ancient Mythology

    PubMed Central

    Behjati-Ardakani, Zohreh; Akhondi, Mohammad Mehdi; Mahmoodzadeh, Homa; Hosseini, Seyed Hasan

    2016-01-01

    Myths are reflective of human concerns and needs during ancient times. By reviewing them, it turns out that many human problems today, have a historical background. Among the main themes of ancient mythologies, fertility and reproduction have various representations in ancient civilizations. The purpose of this paper was to review myths and common symbols of fertility and reproduction in ancient civilizations and evaluate the reasons of their continuous importance in different cultures. The data in this review study was obtained by scrutinizing the related literature. The gathered data indicated the multiplicity and variety of fertility symbols in ancient myths. Most ancient fertility symbols were inspired by the nature and some of them like earth and water were common in mythology of different civilizations. Therefore, the symbols consolidate the concept of conformity between human reproductive concerns and the nature's necessities. PMID:26962477

  15. Agronomic effect of empty fruit bunches compost, anorganic fertilizer and endophytic microbes in oil palm main nursery used Ganoderma endemic soil

    NASA Astrophysics Data System (ADS)

    Hanum, H.; Lisnawita; Tantawi, A. R.

    2018-02-01

    Using of Ganoderma endemic soil in oil palm main nursery is not recomended because produce bad quality seedling. The application of organic and anorganic fertilizer and endophytic microbes are the alternative for solving the problem. The objective of this research is to evaluate the effect of empty fruit bunches compost, anorganic fertilizer and endophytic microbes on growth of oil palm seedling in main nursery. This research used factorial randomized block design. The first factor was combination of empty fruit bunches compost and anorganic fertilizer, The second factor was endophytic microbes consisting of Trichoderma and Aspergillus. The results showed that interaction effect of the both treatment factor used increased growth of seedling in third and fourth month after application. The best growth of seedling was on the treatment of empty fruit bunches compost combined with anorganic fertilizer 150% recommended dosage and Trichoderma viride.

  16. An Evaluation of the Historical Importance of Fertility and Its Reflection in Ancient Mythology.

    PubMed

    Behjati-Ardakani, Zohreh; Akhondi, Mohammad Mehdi; Mahmoodzadeh, Homa; Hosseini, Seyed Hasan

    2016-01-01

    Myths are reflective of human concerns and needs during ancient times. By reviewing them, it turns out that many human problems today, have a historical background. Among the main themes of ancient mythologies, fertility and reproduction have various representations in ancient civilizations. The purpose of this paper was to review myths and common symbols of fertility and reproduction in ancient civilizations and evaluate the reasons of their continuous importance in different cultures. The data in this review study was obtained by scrutinizing the related literature. The gathered data indicated the multiplicity and variety of fertility symbols in ancient myths. Most ancient fertility symbols were inspired by the nature and some of them like earth and water were common in mythology of different civilizations. Therefore, the symbols consolidate the concept of conformity between human reproductive concerns and the nature's necessities.

  17. Occurrence of priority organic pollutants in the fertilizers, China.

    PubMed

    Mo, Ce-Hui; Cai, Quan-Ying; Li, Yun-Hui; Zeng, Qiao-Yun

    2008-04-15

    The use of large quantities of chemical fertilizers is usually associated with environmental problems. A lot of work has been done on the concentrations of heavy metals and radionuclides in chemical fertilizers, but little work has focused on the occurrence of semi-volatile organic compounds (SVOCs). In this study the occurrence of 43 SVOCs listed as priority pollutants in 22 widely used-fertilizers of China was determined by gas chromatography coupled with mass spectrometry. Twenty-six SVOCs were detected with different detection frequencies and concentrations. The most abundant compounds were phthalic acid esters (PAEs; ranging from 1.17 to 2795 microg kg(-1) dry weight, d.w.) and nitroaromatics (up to 9765 microg kg(-1) d.w.), followed by polycyclic aromatic hydrocarbons (PAHs; <140 microg kg(-1) d.w.) and halogenated hydrocarbons (<900 microg kg(-1) d.w.). Chlorobenzenes and haloethers occurred generally at low concentrations. There are large variations in concentrations of various compounds in different fertilizers, and the total concentrations of each class of contaminants varied widely, too. The highest levels of sum concentration for 16 PAHs, for 6 PAEs and for nitroaromatics were found in organic fertilizer containing pesticide and soil amendments. Concentrations of SVOCs in coated fertilizers (the controlled release fertilizer with coating) were considerably higher than those in the corresponding fertilizers without coating. The occurrence frequencies of SVOCs in the straight fertilizers (containing only one of the major plant nutrients) were lower than in the other fertilizers.

  18. Multi-configuration electromagnetic induction measurements at long term agricultural test sites in Germany with different fertilizer and irrigation managements

    NASA Astrophysics Data System (ADS)

    Kaufmann, Manuela Sarah; von Hebel, Christian; Brogi, Cosimo; Baumecker, Michael; Döring, Thomas; Amelung, Wulf; Vereecken, Harry; van der Kruk, Jan

    2017-04-01

    Electromagnetic induction (EMI) data are often being used to investigate large scale soil properties including clay content, soil water content, and salinity changes for a wide range of applications. For agricultural sites, different management practices such as organic/mineral fertilization, tillage, and/or irrigation are important when interpreting the measured apparent electrical conductivity (ECa). Here, we present EMI data recorded at two long term field experiment (LTFE) agricultural test sites in Thyrow near Berlin (Germany), where different long term fertilizer and irrigation management practices were applied. We used two fixed-boom multi-coil EMI instruments that simultaneously measure over nine different depths of investigation (DOI), recording information ranging between the very shallow (0-0.25 m) ploughing zone including the organic matter and the surface soil (A-Horizon) down to the relatively deep (0-2.7 m) subsoil (B-Horizon) or even substratum (C-Horizon). At both test sites, the prevailing sandy to silty sand in the A- and B-Horizon is underlain by a glacial till C-Horizon resulting in generally low ECa values between 0.5 and 5 mS/m. At one test site, a "static nutrient deficiency experiment" is performed since 1937, where organic fertilizer (farm yard manure) and mineral fertilizers (nitrogen-phosphate-potassium (NPK) and liming) are applied at specific grids. Comparing the fertilizer application grid to the measured EMI data, the lowest ECa values coincide to unfertilized grids whereas the ECa values increase with liming, farm yard manure, and NPK. The visually observed correlation between ECa and the liming treatment was possibly due to the increased pH of the soil, because the fertilizer application increases ion contents that increase the soil electrical conductivity. At the second test site, a "Static Irrigation and Fertilizer Experiment" is conducted, where next to the fertilizer treatment (farm yard manure and nitrogen) part of the field is irrigated with a yearly average of 78 mm. Preliminary results show that for the irrigated area, the ECa values increased up to 80% compared to the non-irrigated zones for the deepest sensing coils, whereas farm yard manure increased ECa up to 10% for coils with intermediate DOI. These results obtained at the two LTFE sites strongly indicate that irrigation and fertilizer treatments influence the ion contents of soils from A- to B-Horizons as reflected by the higher apparent electrical conductivities measured with EMI and should be considered when interpreting ECa measurements to obtain soil properties of interest.

  19. Genetic correlations between body condition scores and fertility in dairy cattle using bivariate random regression models.

    PubMed

    De Haas, Y; Janss, L L G; Kadarmideen, H N

    2007-10-01

    Genetic correlations between body condition score (BCS) and fertility traits in dairy cattle were estimated using bivariate random regression models. BCS was recorded by the Swiss Holstein Association on 22,075 lactating heifers (primiparous cows) from 856 sires. Fertility data during first lactation were extracted for 40,736 cows. The fertility traits were days to first service (DFS), days between first and last insemination (DFLI), calving interval (CI), number of services per conception (NSPC) and conception rate to first insemination (CRFI). A bivariate model was used to estimate genetic correlations between BCS as a longitudinal trait by random regression components, and daughter's fertility at the sire level as a single lactation measurement. Heritability of BCS was 0.17, and heritabilities for fertility traits were low (0.01-0.08). Genetic correlations between BCS and fertility over the lactation varied from: -0.45 to -0.14 for DFS; -0.75 to 0.03 for DFLI; from -0.59 to -0.02 for CI; from -0.47 to 0.33 for NSPC and from 0.08 to 0.82 for CRFI. These results show (genetic) interactions between fat reserves and reproduction along the lactation trajectory of modern dairy cows, which can be useful in genetic selection as well as in management. Maximum genetic gain in fertility from indirect selection on BCS should be based on measurements taken in mid lactation when the genetic variance for BCS is largest, and the genetic correlations between BCS and fertility is strongest.

  20. From the bench to bedside to babies: translational medicine made possible by funding multidisciplinary team science.

    PubMed

    Woodruff, Teresa K

    2013-10-01

    In 2005, The National Institutes of Health (NIH) called upon the scientific community to identify the most intractable problems in science and medicine and describe how we would solve these problems using teams. Our group was one of 8 research communities awarded an 'interdisciplinary research consortium (IRC) grant.' Using the infrastructure of this large, multi-institute grant and a team science approach, we set out to solve the problem of fertility loss in young female cancer patients-work that was not easily funded through other mechanisms. The word 'oncofertility' was coined specifically for the IRC to reflect the intimate partnership between oncology care and fertility care for these patients-two disciplines that would no longer function at arms' length, but as an integrated unit. Catalyzed by the IRC funding mechanism, interdisciplinary teams worked together in unique ways to create a 'bench to bedside to baby' outcome. The grant has now ended, and remarkably, so have the most intractable parts of the original problem. As we look back on what worked and look forward to tackling the next set of fertility-related questions, we are confident that this very special NIH funding mechanism made a meaningful difference in the lives of women and their future children. NIH and the public would be well-served by supporting clinical problem-based, multidisciplinary team science approaches to catalyze fundamental biomedical breakthroughs and create new intellectual environments in which changes in clinical practice and standard of care can be implemented.

  1. Impact of fertilization on chestnut growth, N and P concentrations in runoff water on degraded slope land in South China.

    PubMed

    Zeng, Shu-Cai; Chen, Bei-Guang; Jiang, Cheng-Ai; Wu, Qi-Tang

    2007-01-01

    Growing fruit trees on the slopes of rolling hills in South China was causing serious environmental problems because of heavy application of chemical fertilizers and soil erosion. Suitable sources of fertilizers and proper rates of applications were of key importance to both crop yields and environmental protection. In this article, the impact of four fertilizers, i.e., inorganic compound fertilizer, organic compound fertilizer, pig manure compost, and peanut cake (peanut oil pressing residue), on chestnut (Castanea mollissima Blume) growth on a slope in South China, and on the total N and total P concentrations in runoff waters have been investigated during two years of study, with an orthogonal experimental design. Results show that the organic compound fertilizer and peanut cake promote the heights of young chestnut trees compared to the control. In addition, peanut cake increases single-fruit weights and organic compound fertilizer raises single-seed weights. All the fertilizers increased the concentrations of total N and total P in runoff waters, except for organic compound fertilizer, in the first year experiment. The observed mean concentrations of total N varied from 1.6 mg/L to 3.2 mg/L and P from 0.12 mg/L to 0.22 mg/L, which were increased with the amount of fertilizer applications, with no pattern of direct proportion. On the basis of these experiment results, organic compound fertilizer at 2 kg/tree and peanut cake at 1 kg/tree are recommended to maximize chestnut growth and minimize water pollution.

  2. Sexual selection for genetic compatibility: the role of the major histocompatibility complex on cryptic female choice in Chinook salmon (Oncorhynchus tshawytscha).

    PubMed

    Gessner, C; Nakagawa, S; Zavodna, M; Gemmell, N J

    2017-05-01

    Cryptic female choice (CFC), a form of sexual selection during or post mating, describes processes of differential sperm utilization by females to bias fertilization outcomes towards certain males. In Chinook salmon (Oncorhynchus tshawytscha) the ovarian fluid surrounding the ova of a given female differently enhances the sperm velocity of males. Sperm velocity is a key ejaculate trait that determines fertilization success in externally fertilizing fishes, thus the differential effect on sperm velocity might bias male fertilization outcomes and represent a mechanism of CFC. Once sperm reach the oocyte, CFC could potentially be further facilitated by sperm-egg interactions, which are well understood in externally fertilizing marine invertebrates. Here, we explored the potential genetic basis of both possible mechanisms of CFC by examining whether the genotypic combinations of mates (amino-acid divergence, number of shared alleles) at the major histocompatibility complex (MHC) class I and II explain the variation in sperm velocity and/or male fertilization success that is not explained by sperm velocity, which might indicate MHC-based sperm-egg interactions. We recorded sperm velocity in ovarian fluid, employed paired-male fertilization trials and evaluated the fertilization success of each male using microsatellite-based paternity assignment. We showed that relative sperm velocity was positively correlated with fertilization success, confirming that the differential effect on sperm velocity may be a mechanism of CFC in Chinook salmon. The variation in sperm velocity was independent of MHC class I and II. However, the MHC class II divergence of mates explained fertilization success, indicating that this locus might influence sperm-egg interactions.

  3. Urinary paraben concentrations and in vitro fertilization outcomes among women from a fertility clinic.

    PubMed

    Mínguez-Alarcón, Lidia; Chiu, Yu-Han; Messerlian, Carmen; Williams, Paige L; Sabatini, Mary E; Toth, Thomas L; Ford, Jennifer B; Calafat, Antonia M; Hauser, Russ

    2016-03-01

    To explore the relationship between urinary paraben concentrations and IVF outcomes among women attending an academic fertility center. Prospective cohort study. Fertility clinic in a hospital setting. A total of 245 women contributing 356 IVF cycles. None. Quantification of urinary concentrations of parabens by isotope-dilution tandem mass spectrometry, and assessment of clinical endpoints of IVF treatments abstracted from electronic medical records at the academic fertility center. Total and mature oocyte counts, proportion of high-quality embryos, fertilization rates, and rates of implantation, clinical pregnancy, and live births. The geometric means of the urinary concentrations of methylparaben, propylparaben, and butylparaben in our study population were 133, 24, and 1.5 μg/L, respectively. In models adjusted for age, body mass index, race/ethnicity, smoking status, and primary infertility diagnosis, urinary methylparaben, propylparaben, and butylparaben concentrations were not associated with IVF outcomes, specifically total and mature oocyte counts, proportion of high embryo quality, and fertilization rates. Moreover, no significant associations were found between urinary paraben concentrations and rates of implantation, clinical pregnancy, and live births. Urinary paraben concentrations were not associated with IVF outcomes among women undergoing infertility treatments. Copyright © 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  4. Fertilization success of an arctic sea urchin species, Strongylocentrotus droebachiensis (O. F. Müller, 1776) under CO2-induced ocean acidification

    NASA Astrophysics Data System (ADS)

    Bögner, D.; Bickmeyer, U.; Köhler, A.

    2013-05-01

    Sea urchins as broadcasting spawners, release their gametes into open water for fertilization, thus being particularly vulnerable to ocean acidification. In this study, we assessed the effects of different pH scenarios on fertilization success of Strongylocentrotus droebachiensis, collected at Spitsbergen, Arctic. We achieved acidification by bubbling CO2 into filtered seawater using partial pressures (pCO2) of 180, 380, 980, 1400 and 3000 μatm}. Untreated filtered seawater was used as control. We recorded fertilization rates and diagnosed morphological aberrations after post-fertilization periods of 1 h and 3 h under different exposure conditions in experiments with and without pre-incubation of the eggs prior to fertilization. In parallel, we conducted measurements of intracellular pH changes using BCECF/AM in unfertilized eggs exposed to a range of acidified seawater. We observed increasing rates of polyspermy in relation to higher seawater pCO2, which might be due to failures in the formation of the fertilization envelope. In addition, our experiments showed anomalies in fertilized eggs: incomplete lifting-off of the fertilization envelope and blebs of the hyaline layer. Other drastic malformations consisted of constriction, extrusion, vacuolization or degeneration (observed as a gradient from the cortex to the central region of the cell) of the egg cytoplasm, and irregular cell divisions until 2- to 4-cell stages. The intracellular pH (pHi) decreased significantly from 1400 μatm on. All results indicate a decreasing fertilization success at CO2 concentrations from 1400 μatm upwards. Exposure time to low pH might be a threatening factor for the cellular buffer capacity, viability, and development after fertilization.

  5. Spatial and Temporal Variations of Crop Fertilization and Soil Fertility in the Loess Plateau in China from the 1970s to the 2000s

    PubMed Central

    Wang, Xiaoying; Tong, Yanan; Gao, Yimin; Gao, Pengcheng; Liu, Fen; Zhao, Zuoping; Pang, Yan

    2014-01-01

    Increased fertilizer input in agricultural systems during the last few decades has resulted in large yield increases, but also in environmental problems. We used data from published papers and a soil testing and fertilization project in Shaanxi province during the years 2005 to 2009 to analyze chemical fertilizer inputs and yields of wheat (Triticum aestivum L.) and maize (Zea mays L.) on the farmers' level, and soil fertility change from the 1970s to the 2000s in the Loess Plateau in China. The results showed that in different regions of the province, chemical fertilizer NPK inputs and yields of wheat and maize increased. With regard to soil nutrient balance, N and P gradually changed from deficit to surplus levels, while K deficiency became more severe. In addition, soil organic matter, total nitrogen, alkali-hydrolysis nitrogen, available phosphorus and available potassium increased during the same period. The PFP of N, NP and NPK on wheat and maize all decreased from the 1970s to the 2000s as a whole. With the increase in N fertilizer inputs, both soil total nitrogen and alkali-hydrolysis nitrogen increased; P fertilizer increased soil available phosphorus and K fertilizer increased soil available potassium. At the same time, soil organic matter, total nitrogen, alkali-hydrolysis nitrogen, available phosphorus and available potassium all had positive impacts on crop yields. In order to promote food safety and environmental protection, fertilizer requirements should be assessed at the farmers' level. In many cases, farmers should be encouraged to reduce nitrogen and phosphate fertilizer inputs significantly, but increase potassium fertilizer and organic manure on cereal crops as a whole. PMID:25380401

  6. Health psychology meets behavioral economics: introduction to special issue.

    PubMed

    Hanoch, Yaniv; Finkelstein, Eric Andrew

    2013-09-01

    Introduces the special issue of Health Psychology, entitled Health Psychology Meets Behavioral Economics. Psychologists have long been interested in understanding the processes that underlie health behaviors and, based on health behavior models that they have developed, have devised a spectrum of effective prevention and treatment programs. More recently, behavioral economists have also provided evidence of effective behavior change strategies through nonprice mechanisms in a variety of contexts, including smoking cessation, weight loss, and illicit drug use. Yet, although all are addressing similar issues, surprisingly little cross-fertilization has taken place between traditional economists, behavioral economists, and psychologists. This special issue is rooted in the assumption that collaboration between economists and psychologists can promote the development of new methodologies and encourage exploration of novel solutions to enduring health problems. The hope is that readers will be intrigued and inspired by the methodologies used in the different articles and will explore whether they might be applicable to the problems they are addressing. Collaborative efforts, although challenging and at times risky, are a promising way to produce more innovative studies, results, and interventions. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  7. Survey of reasons for discontinuation from in vitro fertilization treatment among couples attending infertility clinic

    PubMed Central

    Kulkarni, Grishma; Mohanty, Nimain C.; Mohanty, Ipseeta Ray; Jadhav, Pradeep; Boricha, B. G.

    2014-01-01

    BACKGROUND: With the increase in infertility burden, more and more couples are opting for in vitro fertilization (IVF). Despite the availability of various treatment options, the major concern that needs to be addressed is the reasons why such couples, initially motivated so strongly, drop out in fairly high numbers from IVF cycles. With this point of view the study was designed. AIM: The objective of this study was to explore the reasons why couples discontinue fertility treatment. SETTINGS AND DESIGN: This retrospective study was carried out among couples in the age group of 20-40 years who opted for IVF at Tertiary care hospital and a private infertility center. MATERIALS AND METHODS: Medical records for 3 years (2009-2012) were taken out and included in the study for analysis. Socio-demographic details along with indication for IVF and reasons for drop-separate IVF therapy were recorded on case record form and were analyzed. RESULTS: Twenty-one percent of the patients had tubal pathology, thus making it the commonest female related factor for indication of IVF. Oligoasthenospermia (13%) was the commonest cause of male related infertility factor. Financial burden was the primary cause for terminating treatment in majority of the IVF cases. CONCLUSIONS: Financial burden (62.5%) was the commonest reason for drop out among couples from IVF cycle. PMID:25624660

  8. The Flipped Classroom: Fertile Ground for Nursing Education Research.

    PubMed

    Bernard, Jean S

    2015-07-16

    In the flipped classroom (FC) students view pre-recorded lectures or complete pre-class assignments to learn foundational concepts. Class time involves problem-solving and application activities that cultivate higher-level cognitive skills. A systematic, analytical literature review was conducted to explore the FC's current state of the science within higher education. Examination of this model's definition and measures of student performance, student and faculty perceptions revealed an ill-defined educational approach. Few studies confirmed FC effectiveness; many lacked rigorous design, randomized samples, or control of extraneous variables. Few researchers conducted longitudinal studies to determine sufficiently trends related to FC practice. This study proves relevant to nurse educators transitioning from traditional teaching paradigms to learner-centered models, and provides insight from faculty teaching across disciplines around the world. It reveals pertinent findings and identifies current knowledge gaps that call for further inquiry.

  9. Identification of factors most important for ammonia emission from fertilized soils for potato production using principal component analysis

    Treesearch

    Guodoong Liu; Yuncong Li; Kati W. Migliaccio; Ying Ouyang; Ashok K. Alva

    2011-01-01

    Ammonia (NH3) emissions from fertilized soils are a costly problem that is undermining agricultural and ecological sustainability worldwide. Ammonia emissions from crop production have been reliably documented in recent years. However, insufficient efforts have been made to determine the factors most influential in facilitating NH3 emissions. The goal of this study was...

  10. Should fertilization treatment start with reducing stress?

    PubMed

    Campagne, Daniel M

    2006-07-01

    In the past few decades, new and more efficient techniques to help solve fertility problems have become widely available throughout the developed world. These techniques include hormonal stimulation, ICSI, gamete intra-Fallopian transfer (GIFT) and IVF, and their cost is, on average, considerable. There is substantial initial evidence that the psychological disposition of the parents-to-be influences their fertility and thus the outcome of fertilization techniques. Many fertility treatments include consultation with a psychologist and do try to keep the stress produced by the treatment itself to a minimum, using concurrent therapy. However, the accumulating evidence points to the need to program medical fertility treatment, bearing in mind both chronic and acute stress levels, and to treat for their reduction before commencing the (actual) fertility treatment. There is ample evidence that lower stress levels mean better female and male natural fertility, though there is as yet no conclusive experimental evidence that lower stress levels result in better fertility treatment outcome. However, first reducing stress may diminish the number of treatment cycles needed before pregnancy is obtained, may prepare the couple for an initial failure of treatment or even make the more invasive techniques unnecessary. Primary psychological treatment for trait and state stress, being a less invasive method than IVF, ICSI or GIFT, is to be applied whenever indicated. Also, treatment and therapy to reduce stress, and in so doing enhance fertility, do not provoke the ethical and religious objections raised by infertility treatments.

  11. [Cystic echinococcosis in children in Tunisia: fertility and case distribution of hydatid cysts].

    PubMed

    Oudni-M'Rad, M; M'Rad, S; Gorcii, M; Mekki, M; Belguith, M; Harrabi, I; Nouri, A; Azaiez, R; Mezhoud, H; Babba, H

    2007-02-01

    Cystic echinococcosis, which commonly starts during childhood or adolescence, is a serious problem of public health in Tunisia. For 121 children (161 cysts), the localization and fertility of cysts as well as viability of their protoscoleces were determined. Results indicated that the lung was the primary localization of cyst (59%) followed by the liver (35%). Children's infection is more frequent in male than in female (sex ratio 1.96) and the greatest number of cases is observed in the 4-9 year age groups (94 cases). The fertility of the cyst was independent of its site or its size and no incidence of age of children was detected. Nevertheless, the fertility rate is higher in females than in males for the liver localization.

  12. From menarche to menopause: the fertile life span of celiac women.

    PubMed

    Santonicola, Antonella; Iovino, Paola; Cappello, Carmelina; Capone, Pietro; Andreozzi, Paolo; Ciacci, Carolina

    2011-10-01

    We evaluated menopause-associated disorders and fertile life span in women with celiac disease (CD) under untreated conditions and after long-term treatment with a gluten-free diet. The participants were 33 women with CD after menopause (untreated CD group), 25 celiac women consuming a gluten-free diet at least 10 years before menopause (treated CD group), and 45 healthy volunteers (control group). The Menopause Rating Scale questionnaire was used to gather information on menopause-associated disorders. The International Physical Activity Questionnaire was used to acquire information on physical activity. Untreated celiac women had a shorter duration of fertile life span than did the control women because of an older age of menarche and a younger age of menopause (P < 0.01). The scores for hot flushes, muscle/joint problems, and irritability were higher in untreated celiac women than in the control women (higher by 49.4%, 121.4%, and 58.6%, respectively; P < 0.05). In comparison with untreated CD, long-lasting treatment of CD was not associated with a significant difference in the duration of fertile life span, but was only associated with a significant reduction in muscle/joint problems (a reduction of 47.1%; P < 0.05). Late menarche and early menopause causes a shorter fertile period in untreated celiac women compared with control women. A gluten-free diet that started at least 10 years before menopause prolongs the fertile life span of celiac women. The perception of intensity of hot flushes and irritability is more severe in untreated celiac women than in controls. Low physical exercise and/or poorer quality of life frequently reported by untreated celiac women might be the cause of reduced discomfort tolerance, thus increasing the subjective perception of menopausal symptoms.

  13. The theoretical and political framing of the population factor in development

    PubMed Central

    Campbell, Martha; Bedford, Kathleen

    2009-01-01

    The silence about population growth in recent decades has hindered the ability of those concerned with ecological change, resource scarcity, health and educational systems, national security, and other global challenges to look with maximum objectivity at the problems they confront. Two central questions about population—(i) is population growth a problem? and (2) what causes fertility decline?—are often intertwined; if people think the second question implies possible coercion, or fear of upsetting cultures, they can be reluctant to talk about the first. The classic and economic theories explaining the demographic transition assume that couples want many children and they make decisions to have a smaller family when some socio-economic change occurs. However, there are numerous anomalies to this explanation. This paper suggests that the societal changes are neither necessary nor sufficient for family size to fall. Many barriers of non-evidence-based restrictive medical rules, cost, misinformation and social traditions exist between women and the fertility regulation methods and correct information they need to manage their family size. When these barriers are reduced, birth rates tend to decline. Many of the barriers reflect a patriarchal desire to control women, which can be largely explained by evolutionary biology. The theoretical explanations of fertility should (i) attach more weight to the many barriers to voluntary fertility regulation, (ii) recognize that a latent desire to control fertility may be far more prevalent among women than previously understood, and (iii) appreciate that women implicitly and rationally make benefit–cost analyses based on the information they have, wanting modern family planning only after they understand it is a safe option. Once it is understood that fertility can be lowered by purely voluntary means, comfort with talking about the population factor in development will rise. PMID:19770159

  14. Design implementation of lean supply chain management: A case study on loading process of fertilizer at PT Petrokimia Gresik port

    NASA Astrophysics Data System (ADS)

    Wibowo, Agus Tri; Handayani, Naniek Utami

    2017-11-01

    Petrokimia Gresik is one of the largest fertilizer producer in Indonesia which has a cross-country network of supply chain and distribution throughout the archipelago, either in bulk fertilizer or in bag fertilizer. This research was conducted at PT. PG port which is the main point of the logistics activities in the firm itself, either loading or unloading. This research focus on the process of loading the in bag fertilizer. Problems that occur in this process are due to the inefficiency of the flow of the Supply Chain, caused by the presence of waste and non-value-added activities. The purpose of this study was to determine what kind of waste that occurs during the process, as well as suggestions for improvements using the concept of Lean Supply Chain and Value Stream Mapping, and look for the cause of the problem using the 5 Whys method. The most influential types of waste during the process stream is Waiting Time (20.42%), and Non-Value Added activies of 51.9%. By using 5Whys, the largest cause of waste found are the length of the truck waiting for the cargo, numbers of crane are already inproper, and the absence of the scheduling and charge allocation. Recommended solutions are scheduling and allocation, creation of special line in the warehouse, and supplying cranes with appropriate load speed. Based on improvement suggestions, total NVA predicted to be reduced to 59.8%.

  15. Synthetic biology approaches to engineering the nitrogen symbiosis in cereals.

    PubMed

    Rogers, Christian; Oldroyd, Giles E D

    2014-05-01

    Nitrogen is abundant in the earth's atmosphere but, unlike carbon, cannot be directly assimilated by plants. The limitation this places on plant productivity has been circumvented in contemporary agriculture through the production and application of chemical fertilizers. The chemical reduction of nitrogen for this purpose consumes large amounts of energy and the reactive nitrogen released into the environment as a result of fertilizer application leads to greenhouse gas emissions, as well as widespread eutrophication of aquatic ecosystems. The environmental impacts are intensified by injudicious use of fertilizers in many parts of the world. Simultaneously, limitations in the production and supply of chemical fertilizers in other regions are leading to low agricultural productivity and malnutrition. Nitrogen can be directly fixed from the atmosphere by some bacteria and Archaea, which possess the enzyme nitrogenase. Some plant species, most notably legumes, have evolved close symbiotic associations with nitrogen-fixing bacteria. Engineering cereal crops with the capability to fix their own nitrogen could one day address the problems created by the over- and under-use of nitrogen fertilizers in agriculture. This could be achieved either by expression of a functional nitrogenase enzyme in the cells of the cereal crop or through transferring the capability to form a symbiotic association with nitrogen-fixing bacteria. While potentially transformative, these biotechnological approaches are challenging; however, with recent advances in synthetic biology they are viable long-term goals. This review discusses the possibility of these biotechnological solutions to the nitrogen problem, focusing on engineering the nitrogen symbiosis in cereals.

  16. A conceptual framework for patient-centered fertility treatment.

    PubMed

    Duthie, Elizabeth A; Cooper, Alexandra; Davis, Joseph B; Schoyer, Katherine D; Sandlow, Jay; Strawn, Estil Y; Flynn, Kathryn E

    2017-09-07

    Patient-centered care is a pillar of quality health care and is important to patients experiencing infertility. In this study we used empirical, in-depth data on couples' experiences of infertility treatment decision making to inform and revise a conceptual framework for patient-centered fertility treatment that was developed based on health care professionals' conceptualizations of fertility treatment, covering effectiveness, burden, safety, and costs. In this prospective, longitudinal mixed methods study, we collected data from both members (separately) of 37 couples who scheduled an initial consult with a reproductive specialist. Data collection occurred 1 week before the initial consultation, 1 week after the initial consultation, and then roughly 2, 4, 8, and 12 months later. Data collection included semi-structured qualitative interviews, self-reported questionnaires, and medical record review. Interviews were recorded, transcribed, and content analyzed in NVivo. A single coder analyzed all transcripts, with > 25% of transcripts coded by a second coder to ensure quality control and consistency. Content analysis of the interview transcripts revealed 6 treatment dimensions: effectiveness, physical and emotional burden, time, cost, potential risks, and genetic parentage. Thus, the revised framework for patient-centered fertility treatment retains much from the original framework, with modification to one dimension (from safety to potential risks) and the addition of two dimensions (time and genetic parentage). For patients and their partners making fertility treatment decisions, tradeoffs are explicitly considered across dimensions as opposed to each dimension being considered on its own. Patient-centered fertility treatment should account for the dimensions of treatment that patients and their partners weigh when making decisions about how to add a child to their family. Based on the lived experiences of couples seeking specialist medical care for infertility, this revised conceptual framework can be used to inform patient-centered treatment and research on infertility and to develop decision support tools for patients and providers.

  17. Iron fertilization of the Subantarctic Ocean during the last ice age

    NASA Astrophysics Data System (ADS)

    Martinez-Garcia, A.

    2015-12-01

    Dust has the potential to modify global climate by influencing the radiative balance of the atmosphere and by supplying iron and other essential limiting micronutrients to the ocean. The scarcity of iron limits marine productivity and carbon uptake in one-quarter of the world ocean where the concentration of major nutrients (phosphorus and nitrogen) is perennially high. The Southern Ocean is the region where variations in iron availability can have the largest effect on Earth's carbon cycle through its fertilizing effect on marine ecosystems. Paleoceanographic records from the Subantarctic Atlantic have revealed a remarkable correlation between phytoplankton productivity and aeolian iron flux during glacial periods supporting the iron fertilization hypothesis. In addition, a recent study has shown that peak glacial times and millennial cold events were nearly universally associated not only with increases in dust flux and export production, but also with an increase in nutrient consumption (the last indicated by higher foraminifera-bound δ15N) (Martinez-Garcia et al. 2014). This combination of changes is uniquely consistent with ice age iron fertilization of the Subantarctic Atlantic. The strengthening of the biological pump associated with the observed increase in Subantarctic nutrient consumption during the high-dust intervals of the last two ice ages can explain up to ~40 ppm of the CO2 decrease that characterizes the transitions from mid-climate states to full ice age conditions. However, the impact of iron fertilization in other sectors of the Southern Ocean characterized by lower ice age dust fluxes than the Atlantic remains unclear. A series of recently published records from the Subantarctic Pacific indicate that dust deposition and marine export production were three times higher during glacial periods than during interglacials (Lamy et al. 2014). Here we present new measurements of foraminifera-bound nitrogen isotopes in a sediment core located in the Subantarctic Pacific (PS75/56-1), which allow us to evaluate the impact of iron fertilization on major nutrient consumption in the largest Southern Ocean sector.

  18. Quantitative analyses of the abundance and composition of ammonia-oxidizing bacteria and ammonia-oxidizing archaea of a Chinese upland red soil under long-term fertilization practices.

    PubMed

    He, Ji-Zheng; Shen, Ju-Pei; Zhang, Li-Mei; Zhu, Yong-Guan; Zheng, Yuan-Ming; Xu, Ming-Gang; Di, Hongjie

    2007-09-01

    The abundance and composition of soil ammonia-oxidizing bacteria (AOB) and ammonia-oxidizing archaea (AOA) were investigated by using quantitative real-time polymerase chain reaction, cloning and sequencing approaches based on amoA genes. The soil, classified as agri-udic ferrosols with pH (H(2)O) ranging from 3.7 to 6.0, was sampled in summer and winter from long-term field experimental plots which had received 16 years continuous fertilization treatments, including fallow (CK0), control without fertilizers (CK) and those with combinations of fertilizer nitrogen (N), phosphorus (P) and potassium (K): N, NP, NK, PK, NPK and NPK plus organic manure (OM). Population sizes of AOB and AOA changed greatly in response to the different fertilization treatments. The NPK + OM treatment had the highest copy numbers of AOB and AOA amoA genes among the treatments that received mineral fertilizers, whereas the lowest copy numbers were recorded in the N treatment. Ammonia-oxidizing archaea were more abundant than AOB in all the corresponding treatments, with AOA to AOB ratios ranging from 1.02 to 12.36. Significant positive correlations were observed among the population sizes of AOB and AOA, soil pH and potential nitrification rates, indicating that both AOB and AOA played an important role in ammonia oxidation in the soil. Phylogenetic analyses of the amoA gene fragments showed that all AOB sequences from different treatments were affiliated with Nitrosospira or Nitrosospira-like species and grouped into cluster 3, and little difference in AOB community composition was recorded among different treatments. All AOA sequences fell within cluster S (soil origin) and cluster M (marine and sediment origin). Cluster M dominated exclusively in the N, NP, NK and PK treatments, indicating a pronounced difference in the community composition of AOA in response to the long-term fertilization treatments. These findings could be fundamental to improve our understanding of the importance of both AOB and AOA in the cycling of nitrogen and other nutrients in terrestrial ecosystems.

  19. Survey report: Kenya.

    PubMed

    Van Der Tak, J

    1986-06-01

    In Kenya, women still average about 8 children each, but the average family size desired by ever-married women dropped by 1 child, from 7.2 to 6.2, between 1978-84. The percentage of currently married women using contraception more than doubled, from 7 to 17%. These are highlights of trends revealed by comparison of the recently released results of the Kenya Contraceptive Prevalence Survey of 1984 with the Kenya Fertility Survey of 1977-78. The latest trends in Kenya's fertility and family planning can be expected to be of worldwide interest in view of the country's record high population growth rate of 4.2% a year. Estimated at 21 million in 1986, the population of Kenya is projected by the UN to quadruple to 83 million by 2025 and could reach as high as 116 million by 2100, according to the World Bank. Among the reasons cited for the failure of Kenya's government family planning program, established in 1968, are bureaucratic snarls, shortages of supplies and trained personnel, and short business hours and long waits in clinics that are not always easily accessible in rural areas. These problems are now being dealt with, but there remains the obstacle of a persistent desire for large families among the population. Over 80% of the 6581 women aged 15-49 interviewed in the 1984 survey knew of at least 1 contraceptive method. The survey report terms the more than doubling of current contraceptive use between 1978-84 as a major success for the family planning program. Yet, the 1984 level is low. Also, the contraceptive mix shifted toward less effective methods. Among currently married women using contraception, the proportion using modern methods was down from 61% in 1978 to 52% in 1984, with oral contraceptive (OC) use dropping from 29 to 19% of the total and rhythm increasing from 16 to 25%. Fertility change was negligible. There was a slight increase in children ever born among women 45-49 from 7.9-8.2 per woman, along with a small decrease in the current total fertility rate from 7.9-7.7 per woman. The 1984 survey found that family size desires and fertility are lower and contraceptive use higher among better educated women. The 1984 survey found little support for the widespread view that Kenyan men are the major obstacle to progress in lowering fertility. Of the reasons for nonuse of contraception given by women who knew of at least 1 method but were not using contraception and were not pregnant, husbands' disapproval accounted for only 9%.

  20. Preliminary observations on polar body extrusion and pronuclear formation in human oocytes using time-lapse video cinematography.

    PubMed

    Payne, D; Flaherty, S P; Barry, M F; Matthews, C D

    1997-03-01

    In this study, we have used time-lapse video cinematography to study fertilization in 50 human oocytes that had undergone intracytoplasmic sperm injection (ICSI). Time-lapse recording commenced shortly after ICSI and proceeded for 17-20 h. Oocytes were cultured in an environmental chamber which was maintained under standard culture conditions. Overall, 38 oocytes (76%) were fertilized normally, and the fertilization rate and embryo quality were not significantly different from 487 sibling oocytes cultured in a conventional incubator. Normal fertilization followed a defined course of events, although the timing of these events varied markedly between oocytes. In 35 of the 38 fertilized oocytes (92%), there were circular waves of granulation within the ooplasm which had a periodicity of 20-53 min. The sperm head decondensed during this granulation phase. The second polar body was then extruded, and this was followed by the central formation of the male pronucleus. The female pronucleus formed in the cytoplasm adjacent to the second polar body at the same time as, or slightly after, the male pronucleus, and was subsequently drawn towards the male pronucleus until the two abutted. Both pronuclei then increased in size, the nucleoli moved around within the pronuclei and some nucleoli coalesced. During pronuclear growth, the organelles contracted from the cortex towards the centre of the oocyte, leaving a clear cortical zone. The oocyte decreased in diameter from 112 to 106 microm (P < 0.0001) during the course of the observation period. The female pronucleus was significantly smaller in diameter than the male pronucleus (24.1 and 22.4 microm respectively, P = 0.008) and contained fewer nucleoli (4.2 and 7.0 respectively, P < 0.0001). After time-lapse recording, oocytes were cultured for 48 h prior to embryo transfer or cryopreservation. Embryo quality was related to fertilization events and periodicity of the cytoplasmic wave, and it was found that good quality embryos arose from oocytes that had more uniform timing from injection to pronuclear abuttal and tended to have a longer cytoplasmic wave. In conclusion, we have shown that time-lapse video cinematography is an excellent tool for studying fertilization and early embryo development, and have demonstrated that human fertilization comprises numerous complex dynamic events.

  1. Sexual selection for genetic compatibility: the role of the major histocompatibility complex on cryptic female choice in Chinook salmon (Oncorhynchus tshawytscha)

    PubMed Central

    Gessner, C; Nakagawa, S; Zavodna, M; Gemmell, N J

    2017-01-01

    Cryptic female choice (CFC), a form of sexual selection during or post mating, describes processes of differential sperm utilization by females to bias fertilization outcomes towards certain males. In Chinook salmon (Oncorhynchus tshawytscha) the ovarian fluid surrounding the ova of a given female differently enhances the sperm velocity of males. Sperm velocity is a key ejaculate trait that determines fertilization success in externally fertilizing fishes, thus the differential effect on sperm velocity might bias male fertilization outcomes and represent a mechanism of CFC. Once sperm reach the oocyte, CFC could potentially be further facilitated by sperm–egg interactions, which are well understood in externally fertilizing marine invertebrates. Here, we explored the potential genetic basis of both possible mechanisms of CFC by examining whether the genotypic combinations of mates (amino-acid divergence, number of shared alleles) at the major histocompatibility complex (MHC) class I and II explain the variation in sperm velocity and/or male fertilization success that is not explained by sperm velocity, which might indicate MHC-based sperm–egg interactions. We recorded sperm velocity in ovarian fluid, employed paired-male fertilization trials and evaluated the fertilization success of each male using microsatellite-based paternity assignment. We showed that relative sperm velocity was positively correlated with fertilization success, confirming that the differential effect on sperm velocity may be a mechanism of CFC in Chinook salmon. The variation in sperm velocity was independent of MHC class I and II. However, the MHC class II divergence of mates explained fertilization success, indicating that this locus might influence sperm–egg interactions. PMID:28051059

  2. Estimates of fertility in Bangladesh.

    PubMed

    D'souza, S; Rahman, S

    1978-01-01

    The attempt is made to estimate fertility levels in Bangladesh on the basis of data collected during the 1974 Census. In the 1st section attention is directed to providing an overall picture of the demographic situation in the country. Comparisons between the 1961 and 1974 data demonstrates that the 1974 Census data provide consistent results. Factors such as the degree of urbanization, literacy and economic participation rates--considered as indicators of development--all seem to show little progress during the intercensal period. The use of child/women ratios (CWRs) provides plausible evidence of the likelihood of a fertility decline. A decline in CWR values is small for "all areas" but a marked decline can be noted for "urban areas." The recorded mean number of children is less in 1974 than in 1961 for women under age 35 whereas for the older groups the 1974 Census shows higher mean numbers. The Bangladesh Fertility Survey (BFS) data result for the total fertility rate of 6.58 is very close to that estimated for the 1974 Census--6.59. The reverse survival method also indicates that birthrates have been lower during the 1969-1974 period.

  3. Sperm characteristics and teratology in rats following vas deferens occlusion with RISUG and its reversal.

    PubMed

    Lohiya, N K; Suthar, R; Khandelwal, A; Goyal, S; Ansari, A S; Manivannan, B

    2010-02-01

    The functional success of the reversal of vas occlusion by styrene maleic anhydride (RISUG), using the solvent vehicle, Dimethyl Sulphoxide (DMSO), has been investigated. Reversal with DMSO was carried out in Wistar albino rats 90 days after bilateral vas occlusion. The body weight, organ weight, sperm characteristics, fertility test and teratology, including skeletal morphology were evaluated in vas occlusion and reversal animals and in F(1) progenies to assess the functional success of the occlusion and reversal. Body weight, organ weight and the cauda epididymal sperm characteristics of vas occlusion and reversal animals and of F(1) progenies were comparable to control. Ejaculated spermatozoa in the vaginal smear showed detached head/tail, acrosomal damage, bent midpiece, bent tail and morphological aberrations in sperm head after vas occlusion, which returned to normal, 90 days after reversal. Monthly fertility test, post-injection showed 0% fertility, which improved gradually and 100% fertility was achieved 90 days after reversal. The fertility/pregnancy/implantation record and skeletal morphology of the offspring were comparable to control. The results suggest functional success and safety of vas occlusion reversal by DMSO.

  4. Income inequality is associated with adolescent fertility in Brazil: a longitudinal multilevel analysis of 5,565 municipalities.

    PubMed

    Chiavegatto Filho, Alexandre D P; Kawachi, Ichiro

    2015-02-07

    Brazil has one of the highest adolescent fertility rates in the world. Income inequality has been frequently linked to overall adolescent health, but studies that analyzed its association with adolescent fertility have been performed only in developed countries. Brazil, in the past decade, has presented a rare combination of increasing per capita income and decreasing income inequality, which could influence future desirable pathways for other countries. We analyzed every live birth from 2000 and from 2010 in each of the 5,565 municipalities of Brazil, a total of 6,049,864 births, which included 1,247,145 (20.6%) births from women aged 15 to 19. Income inequality was assessed by the Gini Coefficient and adolescent fertility by the ratio between the number of live births from women aged 15 to 19 and the number of women aged 15 to 19, calculated for each municipality. We first applied multilevel models separately for 2000 and 2010 to test the cross-sectional association between income inequality and adolescent fertility. We then fitted longitudinal first-differences multilevel models to control for time-invariant effects. We also performed a sensitivity analysis to include only municipality with satisfactory birth record coverage. Our results indicate a consistent and positive association between income inequality and adolescent fertility. After controlling for per capita income, college access, youth homicide rate and adult fertility, higher income inequality was significantly associated with higher adolescent fertility for both 2000 and 2010. The longitudinal multilevel models found similar results. The sensitivity analysis indicated that the results for the association between income inequality and adolescent fertility were robust. Adult fertility was also significantly associated with adolescent fertility in the cross-sectional and longitudinal models. Income inequality is expected to be a leading concern for most countries in the near future. Our results suggest that changes in income inequality are positively and consistently associated with changes in adolescent fertility.

  5. Attachment and sexual functioning in women and men seeking fertility treatment.

    PubMed

    Purcell-Lévesque, Coralie; Brassard, Audrey; Carranza-Mamane, Belina; Péloquin, Katherine

    2018-05-11

    The purpose of the study was to examine the frequency of sexual difficulties and the associations among attachment insecurities (anxiety, avoidance) and sexual functioning (problems with sexual function, sexual dissatisfaction) in women and couples seeking fertility treatment. In a cross-sectional study, 88 Canadian women and 45 couples receiving fertility treatments completed self-reported measures of adult attachment and sexual functioning. The frequency of problems in sexual function varied from 14.8% (pain) to 58.0% (desire) in women and from 6.7% (satisfaction with orgasm) to 28.9% (desire) in men. Among women, attachment-related avoidance predicted their low levels of sexual satisfaction (β = -0.30, p = .007) and sexual pain (β = 0.22, p = .044). Dyadic analyses revealed associations between men's attachment-related anxiety and their difficulties in reaching erection (β = 0.30, p = .042) and orgasm (β = 0.33, p = .009). Anxiety in women was related to their lubrication difficulties (β = 0.44, p = .006). One partner effect was found: men's avoidance was related to their partners' difficulty in achieving orgasms (β = 0.39, p = .045). Results support the pertinence of attachment theory and the relevance of using dyadic designs to understand sexuality in couples seeking fertility treatment.

  6. The impact of controlled nutrition during the dry period on dairy cow health, fertility and performance.

    PubMed

    Beever, David E

    2006-12-01

    Average dairy herd fertility is declining, with more serves per successful conception, extended calving intervals and increased culling due to failure to rebreed, all adding significant costs to milk production. Genetics, management and nutrition have all contributed to this decline in fertility; the paper focuses primarily on nutritional issues. The extent of body condition loss after calving and its possible impact on fertility is considered, with evidence that this phenomenon is common in many herds irrespective of average milk yields. Body tissue mobilisation after calving increases the flux of non-esterified fatty acids to the liver and pathways of fatty acid metabolism are considered. Particular attention is given to the effects of high plasma non-esterified fatty acid levels on fat accumulation in liver cells and possible impacts on nitrogen and glucose metabolism. Current nutritional practices with early lactation cows which aim to stimulate milk yield and peak milk production but have been shown to exacerbate body condition loss, are reviewed. The paper also considers cow health issues during the peri-parturient period and how these may affect milk yield and fertility. It is concluded that current feeding practices for dry cows, with the provision of increasing amounts of the lactation ration during the Close-up period to accustom the rumen microbes and offset the expected reduction in feed intake as pregnancy reaches term, have largely failed to overcome peri-parturient health problems, excessive body condition loss after calving or declining fertility. From an examination of the energy and protein requirements of dry cows, it is suggested that current Close-up feeding practices can lead to luxury intakes of nutrients that can increase fat deposition in the viscera and the liver. Under such conditions, metabolism of nutrients by the cow may be compromised. In contrast, limited feeding throughout the whole dry period has been shown to prevent many of the problems which can affect peri-parturient cows. A new feeding strategy based on a low energy: high fibre ration (9 MJ metabolisable energy and 130 g crude protein/kg ration dry matter) containing high levels of chopped straw and offered ad libitum as a total mixed ration throughout the whole dry period is proposed. The performance of 32 dairy farms in France where this strategy has been adopted for at least 3 years is provided, with positive outcomes now being obtained by UK and Irish dairy farmers. Independent US research evidence has confirmed some of these benefits whilst limited data on cow fertility is presented. It is hypothesised that luxury feeding during the dry period can cause cows to become insulin resistant leading to an increased risk of type II diabetes. Such cows are likely to have poorer fertility whilst possible mechanisms which increase the risk of peri-parturient health problems are discussed. Further research to understand the mechanisms of these effects is required and is currently ongoing. However the magnitude of the effects noted on an increasing number of dairy farms suggests this approach to feeding the dry cow is capable of bringing real benefits to many dairy herds in terms of fewer health problems, reduced body condition loss and improved fertility.

  7. 75 FR 57506 - Summary of Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-21

    ... indirect green goods and services, noting that examples such as USDA approved fertilizers, wind turbine... safety education and compliance related to environmental problems has a beneficial impact on the... health and worker health from the adverse effects of environmental problems. For the reason given in the...

  8. Issues of natural radioactivity in phosphates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schnug, E.; Haneklaus, S.; Schnier, C.

    1996-12-31

    The fertilization of phosphorus (P) fertilizers is essential in agricultural production, but phosphates contain in dependence on their origin different amounts of trace elements. The problem of cadmium (Cd) loads and other heavy metals is well known. However, only a limited number of investigations examined the contamination of phosphates with the two heaviest metals, uranium (U) and thorium (Th), which are radioactive. Also potassium (K) is lightly radioactive. Measurements are done n the radioactivity content of phosphates, P fertilizers and soils. The radiation doses to workers and public as well as possible contamination of soils from phosphate rock or fertilizermore » caused by these elements or their daughter products is of interest with regard to radiation protection. The use of P fertilizers is necessary for a sustainable agriculture, but it involves radioactive contamination of soils. The consequences of the use of P fertilizers is discussed, also with regard to existing and proposed legislation. 11 refs., 2 figs., 7 tabs.« less

  9. Female labour force participation and fertility.

    PubMed

    Concepcion, M B

    1974-01-01

    The levels of labor force participation by women in selected Asian countries were recorded in a series of censuses taken over a period of years. These levels were less influenced than male employment levels by economic conditions and more influenced by cultural traits of the country. Postwar trends seem to have fallen in Korea, risen in Singapore and the Philippines, and remained steady in Japan, Malaya, and Thailand. The limitations of these data are mentioned. In Thailand and West Malaysia greater percentages of women worked in agricultural than non-agricultural employment; in the Philippines, where women did not work so much in agricultural pursuits, their jobs were still in traditional rather than in development industries. In the cities of Bangkok, Manila, and Kuala Lumpur, fertility was lower for working than for non-working women. In rural agricultural areas, the fertility of working women was minimally higher, probably due to economic need of lar ger families. It is concluded that urban life separates the employment and the family roles of working women, leading to lowered fertility; this does not occur in rural areas. The creation of new roles for women alternative or supplementary to marriage and motherhood would result in lowered fertility. In high fertility Asian countries, policies directed toward greater participation of women in non-agricultural work and great er exposure to an urban lifestyle might achieve fertility reductions.

  10. The increase of the fertility of soils using the liquid organic fertilizers and fertilizers based on sugar-beet wastes.

    NASA Astrophysics Data System (ADS)

    Vyborova, Oxana

    2010-05-01

    The fertility of soil is a capacity for ensuring plants by water, nutrients, air and capacity for making optimal conditions for growth and development of plants. The result of it is a yield. The main characteristic of fertility of soil is maintenance of humus. The humus is important part of organic matter. The supporting of soil fertility is impossible by traditional methods. The amount of receiving mineral fertilizers in agriculture will not increase in future, because mineral fertilizers are very expensive. The mineral fertilizers don't influence on maintenance of total amount of humus in soil and improve the circulation of nutrients. Every hectare of fields have to receive no less than 8-10 tons of organic fertilizers, therefore we will have self-supporting balance of humus and the fertility of soils will be increasing. Consequently we are looking for new types of organic materials and we include them in modern agro technologies. One of them is an organomineral fertilizer (lignitic materials). The humic chemicals in the form of lignitic materials of natrium, potassium and ammonium are permitted for using them in agriculture at the beginning of 1984. The Department of agriculture in Russian Federation considered the problem of using humic chemicals and made a decision to use them on the fields of our country, because the lignitic materials can restore the fertility of our fields. The lignitic materials increase the amount of spore-forming bacteria, mold fungi and actinomycete. Therefore the organic decomposition occurs more strongly, the processes of humification increase the speed and the amount of humus rises in the soil. The new forming humus has a high biological activity and it improves chemical and physical soil properties. The addition of lignitic materials in soil activates different groups of microorganisms, which influence on mobilization of nutrients and transformation from potential to effective fertility. The inclusion of humic fertilizers improves physical, physicochemical properties of soils, its air, water and thermal rate. Humic acids with mineral and organomineral particles of soil form the soil absorbent complex. The inclusion of humic fertilizers promotes the process when humic substances form a very valuable water-stable clumpy-granular structure, which improves water-carrying and water-holding capacity, its air permeability by agglutination of mineral particles with each other. The soils, where humic fertilizers are carried in soils regularly, are more stable for influence of chemical polluting substances (for example, radioactive nuclides, heavy metals, pesticides) than poor soils. The inclusion of humic fertilizers is very important in period of urbanization and cropping on the plough-lands not far from a big industrial area. The lignitic materials tie together the detrimental compounds formed the insoluble complex in soil solution. The detrimental compounds don't go into plants, subsoil waters and atmosphere. The lignitic watering of soils (in concentration from 0.1 to 0.01%) increases biological activity of soil in a man-caused zones and it promotes to stability of plants to detrimental emission of enterprises. Today the problem of processing of sugar-beet industry is very important. In the result of storing sugar-beet wastes the pollution of environment is occurred, examples of this pollution are gassing, salinization of soils and ground waters by filtrational sediments. One of these wastes is defecation sludge. The defecation sludge consists of CaCO3, organic matter, nitrogen, phosphorus, potassium and microelements. The technology of receiving N-Ca fertilizer based on defecate was developed because of impossibility of using this waste in pure form. For available data, using of these fertilizers improves the soil fertility and degree of pollution by heavy metals don't exceed an acceptance limits.

  11. Chinese culture and fertility decline.

    PubMed

    Wu, C; Jia, S

    1992-01-01

    Coale has suggested that cultural factors exert a significant influence on fertility reduction; countries in the "Chinese cultural circle" would be the first to show fertility decline. In China, the view was that traditional Chinese culture contributed to increased population. This paper examines the nature of the relationship between Chinese culture and fertility. Attention was directed to a comparison of fertility rates of developing countries with strong Chinese cultural influence and of fertility within different regions of China. Discussion was followed by an explanation of the theoretical impact of Chinese culture on fertility and direct and indirect beliefs and practices that might either enhance or hinder fertility decline. Emigration to neighboring countries occurred after the Qing dynasty. Fertility after the 1950s declined markedly in Japan, Singapore, Hong Kong, South Korea, Taiwan, and mainland China: all countries within the Chinese cultural circle. Other countries within the Chinese circle which have higher fertility, yet lower fertility than other non-Chinese cultural countries, are Malaysia, Thailand, and Indonesia. Within China, regions with similar fertility patterns are identified as coastal regions, central plains, and mountainous and plateau regions. The Han ethnic group has lower fertility than that of ethnic minorities; regions with large Han populations have lower fertility. Overseas Chinese in East Asian countries also tend to have lower fertility than their host populations. Chinese culture consisted of the assimilation of other cultures over 5000 years. Fertility decline was dependent on the population's desire to limit reproduction, favorable social mechanisms, and availability of contraception: all factors related to economic development. Chinese culture affects fertility reduction by affecting reproductive views and social mechanisms directly, and indirectly through economics. Confucianism emphasizes collectivism, self-reliance, education and cultivation of moral character, and atheism. Confucian beliefs that interfere with fertility decline are the advocacy of self-sufficient livelihood, the emphasis on family and lineage, autocracy, patriarchy and feudal rule, the 5 constant virtues, contempt for labor and working people, science and technology, and a closed-door policy. Socialism hindered fertility decline by promoting population growth as a symbol of the superiority of socialism and by lack of recognition of population or environmental problems in socialist countries. The goal is to accept Westernization, reduce obstacles, develop economically, and use cultural influence positive to fertility decline.

  12. HIV/AIDS and Infertility: Emerging Problems in the Era of Highly Active Antiretrovirals

    PubMed Central

    Kushnir, Vitaly A.; Lewis, William

    2011-01-01

    Objective To review the effects of HIV/AIDS, associated co-morbid conditions, and side effects of antiretroviral treatment on fertility. Design A Pubmed computer search was performed to identify relevant articles. Setting Research institution. Intervention(s) None. Result(s) Biological alterations in reproductive physiology may account for sub-fertility in patients infected with HIV. Psychosocial factors in patients with HIV infection may affect reproductive desires and outcomes. Antiretroviral medications may have direct toxicity on gametes and embryos. Available evidence indicates that fertility treatments can be a safe option for HIV-discordant couples; although, potential risk of viral transmission cannot be completely eliminated. Conclusion(s) Reproductive desires are increasingly becoming prominent in the healthcare of young HIV-infected patients. Additional data is needed to address the effect of HIV and its treatments on fertility and reproductive outcomes. PMID:21722892

  13. Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable.

    PubMed

    Zhang, Weidong; Zhao, Yong; Zhang, Pengfei; Hao, Yanan; Yu, Shuai; Min, Lingjiang; Li, Lan; Ma, Dongxue; Chen, Liang; Yi, Bao; Tang, Xiangfang; Meng, Qingshi; Liu, Lei; Wang, Shukun; Shen, Wei; Zhang, Hongfu

    2018-03-01

    Numerous epidemiological studies suggest that air pollutants cause a decline in the quality of human spermatozoa and thus a reduction in fertility. However, the exact cause of infertility remains unknown. Air pollution gases, such as NH 3 and H 2 S are either free or bound to airborne particular materials (PM) and are abundant and reactive. The aim of this current investigation was to explore the impacts of NH 3 and/or H 2 S on male fertility and the underlying mechanisms. Male mouse exposed to H 2 S and/or NH 3 and after two generations were used to evaluate the impacts on fertility. The fertility, and spermatozoa quality parameters and proteins involved in spermatogenesis were investigated. Our current investigation demonstrates: i) H 2 S and/or NH 3 decrease male fertility by 20-30%, reduce the spermatozoa concentration about 20-40%, decrease 10-20%, increase around 30%; ii) the reduction in male fertility by H 2 S and/or NH 3 can be inheritable; iii) H 2 S and/or NH 3 can diminish male fertility through the disruption of spermatogenesis without affecting other body parameters such as body weight and organ index. One component of air pollutants, for example NH 3 , does not have a severe impact; however, two or more pollutants such as H 2 S and NH 3 combined can cause serious health problems, especially with regard to male fertility. We suggest that greater attention should be paid to these air pollutants to improve human health and fertility. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Long-term fate of nitrate fertilizer in agricultural soils.

    PubMed

    Sebilo, Mathieu; Mayer, Bernhard; Nicolardot, Bernard; Pinay, Gilles; Mariotti, André

    2013-11-05

    Increasing diffuse nitrate loading of surface waters and groundwater has emerged as a major problem in many agricultural areas of the world, resulting in contamination of drinking water resources in aquifers as well as eutrophication of freshwaters and coastal marine ecosystems. Although empirical correlations between application rates of N fertilizers to agricultural soils and nitrate contamination of adjacent hydrological systems have been demonstrated, the transit times of fertilizer N in the pedosphere-hydrosphere system are poorly understood. We investigated the fate of isotopically labeled nitrogen fertilizers in a three-decade-long in situ tracer experiment that quantified not only fertilizer N uptake by plants and retention in soils, but also determined to which extent and over which time periods fertilizer N stored in soil organic matter is rereleased for either uptake in crops or export into the hydrosphere. We found that 61-65% of the applied fertilizers N were taken up by plants, whereas 12-15% of the labeled fertilizer N were still residing in the soil organic matter more than a quarter century after tracer application. Between 8-12% of the applied fertilizer had leaked toward the hydrosphere during the 30-y observation period. We predict that additional exports of (15)N-labeled nitrate from the tracer application in 1982 toward the hydrosphere will continue for at least another five decades. Therefore, attempts to reduce agricultural nitrate contamination of aquatic systems must consider the long-term legacy of past applications of synthetic fertilizers in agricultural systems and the nitrogen retention capacity of agricultural soils.

  15. Long-term fate of nitrate fertilizer in agricultural soils

    PubMed Central

    Sebilo, Mathieu; Mayer, Bernhard; Nicolardot, Bernard; Pinay, Gilles; Mariotti, André

    2013-01-01

    Increasing diffuse nitrate loading of surface waters and groundwater has emerged as a major problem in many agricultural areas of the world, resulting in contamination of drinking water resources in aquifers as well as eutrophication of freshwaters and coastal marine ecosystems. Although empirical correlations between application rates of N fertilizers to agricultural soils and nitrate contamination of adjacent hydrological systems have been demonstrated, the transit times of fertilizer N in the pedosphere–hydrosphere system are poorly understood. We investigated the fate of isotopically labeled nitrogen fertilizers in a three–decade-long in situ tracer experiment that quantified not only fertilizer N uptake by plants and retention in soils, but also determined to which extent and over which time periods fertilizer N stored in soil organic matter is rereleased for either uptake in crops or export into the hydrosphere. We found that 61–65% of the applied fertilizers N were taken up by plants, whereas 12–15% of the labeled fertilizer N were still residing in the soil organic matter more than a quarter century after tracer application. Between 8–12% of the applied fertilizer had leaked toward the hydrosphere during the 30-y observation period. We predict that additional exports of 15N-labeled nitrate from the tracer application in 1982 toward the hydrosphere will continue for at least another five decades. Therefore, attempts to reduce agricultural nitrate contamination of aquatic systems must consider the long-term legacy of past applications of synthetic fertilizers in agricultural systems and the nitrogen retention capacity of agricultural soils. PMID:24145428

  16. Genome-wide Association Studies for Female Fertility Traits in Chinese and Nordic Holsteins.

    PubMed

    Liu, Aoxing; Wang, Yachun; Sahana, Goutam; Zhang, Qin; Liu, Lin; Lund, Mogens Sandø; Su, Guosheng

    2017-08-16

    Reduced female fertility could cause considerable economic loss and has become a worldwide problem in the modern dairy industry. The objective of this study was to detect quantitative trait loci (QTL) for female fertility traits in Chinese and Nordic Holsteins using various strategies. First, single-trait association analyses were performed for female fertility traits in Chinese and Nordic Holsteins. Second, the SNPs with P-value < 0.005 discovered in Chinese Holsteins were validated in Nordic Holsteins. Third, the summary statistics from single-trait association analyses were combined into meta-analyses to: (1) identify common QTL for multiple fertility traits within each Holstein population; (2) detect SNPs which were associated with a female fertility trait across two Holstein populations. A large numbers of QTL were discovered or confirmed for female fertility traits. The QTL segregating at 31.4~34.1 Mb on BTA13, 48.3~51.9 Mb on BTA23 and 34.0~37.6 Mb on BTA28 shared between Chinese and Nordic Holsteins were further ascertained using a validation approach and meta-analyses. Furthermore, multiple novel variants identified in Chinese Holsteins were validated with Nordic data as well as meta-analyses. The genes IL6R, SLC39A12, CACNB2, ZEB1, ZMIZ1 and FAM213A were concluded to be strong candidate genes for female fertility in Holsteins.

  17. Effects of Fertility on Gene Expression and Function of the Bovine Endometrium

    PubMed Central

    Minten, Megan A.; Bilby, Todd R.; Bruno, Ralph G. S.; Allen, Carolyn C.; Madsen, Crystal A.; Wang, Zeping; Sawyer, Jason E.; Tibary, Ahmed; Neibergs, Holly L.; Geary, Thomas W.; Bauersachs, Stefan; Spencer, Thomas E.

    2013-01-01

    Infertility and subfertility are important and pervasive reproductive problems in both domestic animals and humans. The majority of embryonic loss occurs during the first three weeks of pregnancy in cattle and women due, in part, to inadequate endometrial receptivity for support of embryo implantation. To identify heifers of contrasting fertility, serial rounds of artificial insemination (AI) were conducted in 201 synchronized crossbred beef heifers. The heifers were then fertility classified based on number of pregnancies detected on day 35 in four AI opportunities. Heifers, classified as having high fertility, subfertility or infertility, were selected for further study. The fertility-classified heifers were superovulated and flushed, and the recovered embryos were graded and then transferred to synchronized recipients. Quantity of embryos recovered per flush, embryo quality, and subsequent recipient pregnancy rates did not differ by fertility classification. Two in vivo-produced bovine embryos (stage 4 or 5, grade 1 or 2) were then transferred into each heifer on day 7 post-estrus. Pregnancy rates were greater in high fertility than lower fertility heifers when heifers were used as embryo recipients. The reproductive tracts of the classified heifers were obtained on day 14 of the estrous cycle. No obvious morphological differences in reproductive tract structures and histology of the uterus were observed in the heifers. Microarray analysis revealed differences in the endometrial transcriptome based on fertility classification. A genome-wide association study, based on SNP genotyping, detected 7 moderate associations with fertility across 6 different chromosomes. Collectively, these studies support the idea that innate differences in uterine function underlie fertility and early pregnancy loss in ruminants. Cattle with defined early pregnancy success or loss is useful to elucidate the complex biological and genetic mechanisms governing endometrial receptivity and uterine competency for pregnancy. PMID:23940519

  18. Synectics: An Explanation of the Process and Some Comments on its Application in the Secondary School.

    ERIC Educational Resources Information Center

    Marran, James F.; Rogan, Donald V.

    Synectics is a method of creative problem solving through the use of metaphor and apparent irrelevancy developed by William J. J. Gordon. The process involves rational knowledge of the problem to be solved, irrational improvisations that lead to fertile associations creating new approaches to the problem, and euphoric state that is essential in…

  19. Polygyny among the Tsimane of Bolivia: an improved method for testing the polygyny–fertility hypothesis

    PubMed Central

    Winking, Jeffrey; Stieglitz, Jonathan; Kurten, Jenna; Kaplan, Hillard; Gurven, Michael

    2013-01-01

    The polygyny–fertility hypothesis states that polygyny is associated with reduced fertility for women and is supported by a large body of literature. This finding is important, because theoretical models of polygyny often differentiate systems based on the degree to which women are forced or willingly choose to enter polygynous marriages. The fact that polygyny tends to be associated with reduced fertility has been presented as evidence that polygyny is often less favourable for women, and that women must, therefore, be pressured into accepting such arrangements. Previous studies, however, have been hampered by the non-random assignment of women into monogamous and polygynous unions (i.e. self-selection), as differences between these groups of women might explain some of the effects. Furthermore, the vast majority of such studies focus on sub-Saharan populations. We address these problems in our analysis of women's fertility in polygynous marriages among the Tsimane of Bolivia. We offer a more robust method for assessing the impact of polygynous marriage on reproductive outcomes by testing for intra-individual fertility effects among first wives as they transition from monogamous to polygynous marriage. We report a significant link between polygyny and reduced fertility when including all cases of polygyny; however, this association disappears when testing only for intra-individual effects. PMID:23407840

  20. Update on fertility preservation in young women undergoing breast cancer and ovarian cancer therapy.

    PubMed

    Lambertini, Matteo; Ginsburg, Elizabeth S; Partridge, Ann H

    2015-02-01

    The purpose of the article is to review the available options for fertility preservation in patients with breast and ovarian cancer, and the special issues faced by BRCA mutation carriers. Future fertility is an important consideration for many young patients with cancer. There are both experimental and standard available strategies for patients with breast and ovarian cancer to preserve fertility, and each has potential advantages and disadvantages. Embryo cryopreservation is widely available with a highly successful track record. Improvements in laboratory techniques have led to oocyte cryopreservation recently being recategorized as nonexperimental. Conservative gynecologic surgery is a standard consideration for patients with stage I ovarian cancer who desire future fertility. Ovarian tissue cryopreservation as well as ovarian suppression with luteinizing hormone-releasing hormone analogs during chemotherapy are considered experimental methods at this time, although recent data suggest both safety and efficacy for the use of luteinizing hormone-releasing hormone analogs in women receiving (neo)adjuvant chemotherapy for breast cancer. Special issues should be considered for women with BRCA mutations because of the need to undergo preventive surgery at young age. Multidisciplinary teams and well functioning relationships between the oncology and reproductive units are crucial to manage the fertility issues of young women with cancer.

  1. China Report, Economic Affairs, Energy: Status and Development -- XXVII

    DTIC Science & Technology

    1984-04-30

    dangerous effects on communications lines was an investment of 60 million yuan. The root of the problem is that the posts and telecommunications departments...of the farm- land in China relies solely on chemical fertilizer, a lot of it impure chemi- cal fertilizer. The results are very poor. Rarely do they...Do Research in Plants for Energy We must do research in the organic and ecological characteristics of cassava , sweet potatoes, and other starchy

  2. Psychosocial aspects of infertility and its treatment.

    PubMed

    Malina, Alicja; Błaszkiewicz, Anna; Owczarz, Urszula

    2016-01-01

    Nowadays, more and more couples face impediments associated with conception. Infertility is related with experiencing psychological problems by both partners. One of the infertility treatment procedures is in vitro fertilization. Using this method has significant influence on patients and their family's psychology. This essay reviews literature about IVF treatment and discusses the significance of infertility to a couple, children development and psychosocial functioning, their relation with parents and public opinion about in vitro fertilization.

  3. Dioxin levels in fertilizers from Belgium: determination and evaluation of the potential impact on soil contamination.

    PubMed

    Elskens, M; Pussemier, L; Dumortier, P; Van Langenhove, K; Scholl, G; Goeyens, L; Focant, J F

    2013-06-01

    Dioxins are harmful persistent organic pollutants (POPs) to which humans are exposed mostly via the consumption of animal products. They can enter the food chain at any stage, including crop fertilization. Fertilizers belong to several categories: synthetic chemicals providing the essential elements (mostly N, P and K) that are required by the crops but also organic fertilizers or amendments, liming materials, etc. Ninety-seven samples of fertilizers were taken in Belgium during the year 2011 and analyzed after a soft extraction procedure for polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and dioxin-like polychlorinated biphenyls (DL-PCBs) using GC-IDHRMS. Only small qualitative differences could be observed between the main fertilizer categories since the PCDD:PCDF:DL-PCB average ratio obtained with the results expressed in TEQ was often close to 30:30:40 (typically for sewage sludge) or 40:30:30 (typically for compost). The median dioxin levels determined were generally lower than recorded previously and were the highest for sewage sludge and compost (5.6 and 5.5 ng TEQ/kg dry weight (dw), respectively). The levels in other fertilizers were lower including manure for which the median value was only 0.2 ng TEQ/kg dw. Several fertilization scenarios relying on the use of those fertilizers were assessed taking into consideration the application conditions prevailing in Belgium. From this assessment it could be concluded that the contribution of fertilizers to the overall soil contamination will be low by comparison of other sources of contamination such as atmospheric depositions. At the field scale, intensive use of compost and sewage sludge will increase dramatically the dioxin inputs compared with other fertilization practices but this kind of emission to the soil will still be relatively low compared to the dioxin atmospheric depositions. Copyright © 2013 Elsevier B.V. All rights reserved.

  4. Immunizations for the college student: a campus perspective of an outbreak and national and international considerations.

    PubMed

    Kumar, Ashir; Murray, Dennis L; Havlichek, Daniel H

    2005-02-01

    Although vaccine-preventable diseases have declined to record-low levels in the United States, infectious disease "epidemics" on college campuses continue. A large student body with variable immunization status makes a college campus fertile ground for the spread of communicable diseases. The presence of international students and an increasingly large number of students traveling abroad make it essential that individuals charged with defining and instituting health-related policies for the university have knowledge about health issues occurring in foreign countries as well. Several safe and effective vaccines are available that offer protection to young adults from a variety of infectious diseases in the United States. Because vaccine-preventable diseases can cause both human and economic problems for colleges and universities, administrators should take steps to assure that the students on college campuses benefit from these vaccines.

  5. Young Men With Cancer Experience Low Referral Rates for Fertility Counseling and Sperm Banking.

    PubMed

    Grover, Natalie S; Deal, Allison M; Wood, William A; Mersereau, Jennifer E

    2016-05-01

    With improved cancer survival rates and the current trend of delaying parenthood, fertility is a growing issue among cancer patients. The purpose of this study was to evaluate the incidence of fertility counseling and sperm banking in reproductive-age male cancer patients and to assess factors that influence counseling and banking. Male patients ages 13 to 50 years who received a new cancer diagnosis from January 1, 2013, to May 1, 2015, and planned to initiate curative chemotherapy at our center were identified. Documentation of fertility counseling and sperm cryopreservation was abstracted from the medical record. Univariable and multivariable logistic regression modeling was used to examine variables associated with fertility counseling and sperm banking. Of 201 patients who fit the study criteria, 59 (29%) received fertility counseling and 23 (11%) attempted sperm banking. All patients who banked sperm had documentation of fertility counseling. Younger patients were significantly more likely to be counseled, with mean ages of 27.4 and 40.4 years for counseled and noncounseled patients, respectively (P < .001). Among counseled patients, those with a lower median income (P = .038) or who had Medicaid or no insurance (P = .042) were less likely to bank sperm. In a multivariable logistic regression model, older age (5-year odds ratio, 0.61; P < .001) and presence of comorbidities (odds ratio, 0.15; P = .03) remained significantly associated with a lower counseling rate. There is a low rate of fertility counseling and referral for sperm banking in young men with cancer receiving chemotherapy. Further work is needed to develop interventions to improve fertility counseling rates and opportunities for sperm banking. Copyright © 2016 by American Society of Clinical Oncology.

  6. [Reflections on the demographic future of advanced societies: a Canadian perspective].

    PubMed

    Romaniuc, A

    1990-01-01

    3 different perspectives on the below-replacement fertility in Quebec and in Canada are defined and discussed, and the possibility that political solutions will be sought for the demographic problem of low fertility is assessed. The 1st perspective views very low fertility as an outcome of social evolution that is common to advanced societies. In this view, the deeper reasons for low fertility can ultimately be traced to the rationalism, utilitarianism, and individualism produced by the age of enlightenment, and to the industrial revolution, which gave human beings improved control over fertility and modified the psychology and context of reproduction. Events involved in the post-baby boom fertility decline include development of very effective contraception, massive entry of women into the labor force, heightened consumption standards and desires, the rise of social security systems, and a lessened interest in children and family life generally. A 2nd perspective views low fertility as part of a self-regulating social process. Various mechanisms can be proposed by which fertility could spontaneously increase without any undesirable government intervention. Children, having become relatively rare, could become more highly desired as consumer goods. Fashions could change, and the current period of low fertility and abandonment of family values could be succeeded by a period of family renewal. Or the demographic implosion in the industrial world could lead to improved balance between population and environment, after which grouth could resume. But there is little evidence that the personal interest of couples in having children will suddenly correspond to collective interests. The 3rd perspective views demographic problems as matters of public choice and is founded on the notion that society has the capacity to mold its destiny. The will of society to do so is questionable, however, and the history of debates over the desirability of providing universal primary education or health care may be relevant to the question of public acceptance of a family policy. 4 relatively new arguments have emerged that may influence the debate: public opinion on profamily programs and their social contribution is becoming more favorable, and there is growing awareness that income disparities between men and women are related to the family responsibilities of women; that the coming demographic regime of very low fertility and increasing age of the population is historically unprecedented; and that the fertility change needed to assure replacement or moderate growth is relatively modest. Against these factors is the high cost of a family policy. It appears that a synthesis of the 3 theoretical positions is needed which would recognize the realities of a society that has reached demographic maturity while affirming a will to modify some of its trends.

  7. Communication difficulties and the experience of loneliness in patients with cancer dealing with fertility issues: a qualitative study.

    PubMed

    Goossens, Joline; Delbaere, Ilse; Beeckman, Dimitri; Verhaeghe, Sofie; Van Hecke, Ann

    2015-01-01

    To explore communication difficulties and the experience of loneliness among patients with cancer dealing with fertility issues. Qualitative study based on grounded theory principles. One university hospital and two general hospitals in Flanders, Belgium. 21 female and 7 male patients with cancer with potential fertility problems as a result of treatment. Grounded theory approach using the constant comparison method; data collection (semistructured face-to-face interviews) and analysis occurred simultaneously. Loneliness was a central theme in the experience of potential fertility loss among patients with cancer. Feelings of loneliness resulted from communication difficulties between the patient and members of his or her social environment or healthcare professionals because of several underlying processes and influencing factors. Loneliness was a strong and common feeling among patients with cancer. Patients, members of their social environment, and healthcare professionals experienced difficulties in communicating about fertility in the context of cancer, leading to patients' feelings of loneliness. Healthcare professionals must be attentive to signs indicating loneliness regarding fertility concerns, and they should provide adequate information and appropriate guidance to support patients. Professionals need further training to improve knowledge and skills.

  8. Morphologic interpretation of fertile structures in glossopterid gymnosperms

    USGS Publications Warehouse

    Schopf, J.M.

    1976-01-01

    The problem of determining affinity among glossopterid gymnosperms is beset by deficiencies in preservation, natural dissociation of parts, and scarcity of features assuredly critical for morphologic comprarison. The glossopterids probably are not a very heterogeneous group of plants, but this is difficult to prove. The Gondwana glacial "hiatus" has resulted in the omission of a critical chapter glossopterid evolution. As a consequence, morphologic features and phyletic probabilities must be evaluated on a much more hypothetical basis than would otherwise be justified. Confusion has arisen from the lack of morphologic terms that permit clear discussion of a newly evolved type of reproductive structure in glossopterids. The structure, here designated a "fertiliger", consists of a leafy bract, a partially adnate stalk, and a fertile head or capitulum. Seven types of fertile structures are discussed, all of which are bilaterally symmetrical and have different features on dorsiventral surfaces. I regard all fertiligers as ovulate but this interpretation may bot be acceptable to some workers; others may not accept dorsiventral organization of the capitulum as being fundamental. Among glossopterids, however, in spite of differences in preservation that may seem to support a variant interpretation, these ovulate fertiligers are the distinctive features that show general consistency. A single fertile bract bearing several capitula, as exemplified by Lidgettonia, is called a compound fertiliger. Staminate structures (microsporophylls) of glossopterids are separately classified as Eretmonia, Glossotheca, and possibly as other taxa. Only the manner of sporangial attachment is not entirely clear. It seems likely the staminate parts have previously been confused with scale leaves and are actually coextensive in distribution with the glossopterids. A tentative phyletic model suggests the distant derivation of glossopterids from middle Carboniferous cordaiteans. Many details must be speculative due to the lack of a pertinent fossil record, but this interpretation accounts for some features that have no counterpart in pteridosperms. Permineralized ovules from Antarctica provide general support for this working hypothesis, but specific evidence is lacking. Furthermore, it seems unlikely angiosperms originated from glossopterids; it is more reasonable to consider the glossopterids as possible distant ancestors of the Gnetales. ?? 1976.

  9. Unplanned Pregnancies, Family Planning Problems, and Child Maltreatment.

    ERIC Educational Resources Information Center

    Zuravin, Susan J.

    1987-01-01

    Examined the relationship between contracepting problems, unplanned fertility, and both child abuse and neglect in 518 urban, single parent, public assistance mothers. Findings revealed that increasing numbers of unplanned conceptions increased the probability of both abuse and neglect and that the unplanned conceptions were due to both failure to…

  10. Conclusions and Recommendations of the Strategy Consulation on Adolescent Fertility.

    ERIC Educational Resources Information Center

    Population Inst., Washington, DC.

    The problem of adolescent pregnancy and childbearing is addressed. The document is a result of a conference of youth service agencies, family planning organizations, policy makers, health service providers, and leaders in sex education. Following summaries of participants' discussion of the nature of the problem and strategies for program…

  11. Temporal Trends in Fertility Rates: A Nationwide Registry Based Study from 1901 to 2014.

    PubMed

    Blomberg Jensen, Martin; Priskorn, Lærke; Jensen, Tina Kold; Juul, Anders; Skakkebaek, Niels Erik

    2015-01-01

    Increasing age at first childbirth has been suggested to increase the risk for infertility. Our objective is to determine whether women above thirty years of age historically have been able to sustain fertility rates above replacement level. A descriptive nationwide Danish study using birth registries from 1901-2014. Information on women's age at childbirth was obtained by using records from primary, secondary and tertiary institutions. Mothers to 8,024,969 live births. Mothers were stratified according to age at childbirth to determine total and age specific fertility rates. Total fertility rate (TFR) decreased from 4.1 to 1.8 children per woman and age specific fertility also decreased from 1901 to 2014. Women aged 30-34, 35-39 or 40-44 years in the first decade of the 20th century had higher fertility rates than the corresponding five year younger age groups (25-29, 30-34 and 35-39, respectively) have had for the last 65 years. On average, women gave birth to two children after the age of 30 and one or more child after 35 years of age in the beginning of the 1900s. Furthermore, women more than 40 years of age accounted for 10% of TFR in 1901 compared with 4% in 2014 despite usage of assisted reproduction. This nationwide study shows that women above 30 years of age historically have been able to sustain fertility rates above replacement level. This implies that other factors besides age are strong determinants of fertility in women above 30 years of age.

  12. The study of fertility and fertility change in tropical Africa.

    PubMed

    Caldwell, J C

    1976-09-01

    This paper explores what little is known about fertility and fertility trends in tropical Africa and methods for obtaining more information. The most fundamental barrier at present is failure to make the fullest effort in applying the techniques that are available to already collected data. Present emphasis should be on elucidating the forces that sustain higher fertility and factors that may lead to changing fertility from smaller studies of high quality design. Currently available data have many errors and the region is at an early stage of demographic transition: vital registration schemes are nonexistent, survey and census data are so incomplete that vital rates worked out directly from the data are of little value, and fertility is probably close to being constant. Despite the ability of new methods for data analysis, e.g., Brass, Coale Demeny approach, problems exist in the following areas ascertaining fertility changes: methodological limitations, collection of data, and the detection and prediction of fertility change. Present fertility findings are summarized, the most significant being that tropical African fertility is not far above stated desired family size, which is very high in comparison with the rest of the world. Sources of data for making statements about fertility behavior are explored and research needs delineated. Priority areas should include: better fertility measures; more KAP type information for francophone Africa; emphasis on links between antinatal practice and fertility levels; study of 1 country over time using KAP indicators; motivations for fertility control; real cost of children at village family level; spread of antinatal practices, finding measures of completed behavior; and exploration of the financing of children's education in relation to attempts to limit family size. The Changing African Family Project, planned as a collaborative effort by researchers in more than 10 countries and designed to answer these questions, is described in detail. Countries and groups surveyed included the Yoruba of Western and Lagos States in Nigeria. Specific survey methodology and findings are explained for the "Value of Children" survey, the "Beginning of Family Limitation" survey, and the "Achieved Small Family" survey, all components of the project.

  13. Unresolved issues in mammalian fertilization.

    PubMed

    Olds-Clarke, Patricia

    2003-01-01

    This review considers the role of the sperm in fertilization, addressing areas of misunderstanding and unfounded assumptions and taking particular advantage of the large body of data resulting from work with rodent species in vitro. Considerable attention is given to the appropriate use and interpretation of assays for capacitation, acrosomal exocytosis, hyperactivation, and sperm protein phosphorylation, as well as tests for sperm-zona and sperm-oocyte membrane interactions. The lack of general agreement on the means of sperm adhesion to and penetration of the zona pellucida is addressed, and the need for new approaches to this problem is pointed out. Some molecular advances in our understanding of specific steps in the process of fertilization are discussed in the context of intact cell-matrix and cell-cell interaction. This review should provide practical information for researchers just beginning the study of fertilization and interesting but not widely known observations to stimulate new ideas in experienced scientists.

  14. Barriers to fertility regulation: a review of the literature.

    PubMed

    Campbell, Martha; Sahin-Hodoglugil, Nuriye Nalan; Potts, Malcolm

    2006-06-01

    The evidence in the demographic and family planning literature of the range and diversity of the barriers to fertility regulation in many developing countries is reviewed in this article from a consumer perspective. Barriers are defined as the constraining factors standing between women and the realistic availability of the technologies and correct information they need in order to decide whether and when to have a child. The barriers include limited method choice, financial costs, the status of women, medical and legal restrictions, provider bias, and misinformation. The presence or absence of barriers to fertility regulation is likely an important determinant of the pace of fertility decline or its delay in many countries. At the same time, barriers inhibit women's ability to avoid unintended pregnancy. Problems of quantifying barriers limit understanding of their importance. New ways to quantify them and to identify misinformation, which is often concealed in survey data, are needed for future research.

  15. Definitions and the experience of fertility problems: infertile and sub-fertile women, childless mothers, and honorary mothers in two southern Nigerian communities.

    PubMed

    Whitehouse, Bruce; Hollos, Marida

    2014-03-01

    Although infertility causes women considerable grief, social stigma, and economic deprivation, scholars have paid little attention to infertility's definitions that may depart from the standard Western usage and how such definitions influence the way women experience the condition. This article, by listening to individual women's experiences of infertility in two Nigerian communities, examines these definitions and differentiates between culturally salient categories of infertility. In distinguishing between different kinds of childless women and those with low fertility, we intend to enhance understandings of infertility by considering women's subjective understandings of the condition and thus moving beyond the current medical definition. By comparing women's experiences in two different ethnic groups in Nigeria, we show how distinct forms of kinship structures and social organizations shape the ways low fertility is defined, managed, and experienced. © 2013 by the American Anthropological Association.

  16. Bayes plus Brass: Estimating Total Fertility for Many Small Areas from Sparse Census Data

    PubMed Central

    Schmertmann, Carl P.; Cavenaghi, Suzana M.; Assunção, Renato M.; Potter, Joseph E.

    2013-01-01

    Small-area fertility estimates are valuable for analysing demographic change, and important for local planning and population projection. In countries lacking complete vital registration, however, small-area estimates are possible only from sparse survey or census data that are potentially unreliable. Such estimation requires new methods for old problems: procedures must be automated if thousands of estimates are required, they must deal with extreme sampling variability in many areas, and they should also incorporate corrections for possible data errors. We present a two-step algorithm for estimating total fertility in such circumstances, and we illustrate by applying the method to 2000 Brazilian Census data for over five thousand municipalities. Our proposed algorithm first smoothes local age-specific rates using Empirical Bayes methods, and then applies a new variant of Brass’s P/F parity correction procedure that is robust under conditions of rapid fertility decline. PMID:24143946

  17. Definitions and the Experience of Fertility Problems: Infertile and Sub-fertile Women, Childless Mothers, and Honorary Mothers in Two Southern Nigerian Communities

    PubMed Central

    Whitehouse, Bruce; Hollos, Marida

    2015-01-01

    Although infertility causes women considerable grief, social stigma, and economic deprivation, scholars have paid little attention to infertility’s definitions that may depart from the standard Western usage and how such definitions influence the way women experience the condition. This article, by listening to individual women’s experiences of infertility in two Nigerian communities, examines these definitions and differentiates between culturally salient categories of infertility. In distinguishing between different kinds of childless women and those with low fertility, we intend to enhance understandings of infertility by considering women’s subjective understandings of the condition and thus moving beyond the current medical definition. By comparing women’s experiences in two different ethnic groups in Nigeria, we show how distinct forms of kinship structures and social organizations shape the ways low fertility is defined, managed, and experienced. PMID:24578250

  18. Biokinetic model-based multi-objective optimization of Dunaliella tertiolecta cultivation using elitist non-dominated sorting genetic algorithm with inheritance.

    PubMed

    Sinha, Snehal K; Kumar, Mithilesh; Guria, Chandan; Kumar, Anup; Banerjee, Chiranjib

    2017-10-01

    Algal model based multi-objective optimization using elitist non-dominated sorting genetic algorithm with inheritance was carried out for batch cultivation of Dunaliella tertiolecta using NPK-fertilizer. Optimization problems involving two- and three-objective functions were solved simultaneously. The objective functions are: maximization of algae-biomass and lipid productivity with minimization of cultivation time and cost. Time variant light intensity and temperature including NPK-fertilizer, NaCl and NaHCO 3 loadings are the important decision variables. Algal model involving Monod/Andrews adsorption kinetics and Droop model with internal nutrient cell quota was used for optimization studies. Sets of non-dominated (equally good) Pareto optimal solutions were obtained for the problems studied. It was observed that time variant optimal light intensity and temperature trajectories, including optimum NPK fertilizer, NaCl and NaHCO 3 concentration has significant influence to improve biomass and lipid productivity under minimum cultivation time and cost. Proposed optimization studies may be helpful to implement the control strategy in scale-up operation. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. [The paradox of motherhood].

    PubMed

    Ouaidou, N G

    1990-08-01

    All Sahelian countries are working to define their population policies. A population policy document avoids dispersion and duplication. It opens the path to efficiency. It makes it easier to achieve governmental socioeconomic objectives. Various recent population-related meetings have at least two points in common: they aim to overstep and improve a given situation and are at the same time some examples of implementing the Ndjamena action program, adopted in January 1989. All these population-centered actions return to the problem of adolescent fertility--a poignant problem. Adolescent pregnancy is a major source of family and social break-ups. This paradox of motherhood makes a violent storm burst in the skies ordinarily serene with joy and hope. It is an enemy perverse to economic development and social progress. Adolescent motherhood is a phenomenon which complicates and aggravates population problems and is taboo to the point it is still imperceptible, unknown. It is a problem of premier importance in the Sahel. Pregnancy strikes a woman so very unprepared for motherhood and its demands. It risks the life of a being which is preparing itself to enter the world. Adolescent pregnancy has equally tragic health effects: poorly performed underground abortions and maternal and infant deaths. Adolescent fertility is a burning problem regardless of the perspective (demographic, economic, social, or health). In Sahelian countries, one is beginning to be interested in and to speak about it. It will be necessary to search for solutions. Schools must be a top target for all activities aiming to check adolescent fertility. The emphasis must be on information, education, and responsibility of girls, boys, teachers, and parents. Education and training are of capital importance for socioeconomic development of the Sahel. All activities implemented in the education sector should include a large place for family life education in pregnancy prevention.

  20. [Relationships between psychological well-being, lifestyle factors and fertility].

    PubMed

    Lakatos, Enikő; Szabó, Gábor; F Szigeti, Judit; Balog, Piroska

    2015-03-22

    10 to 15% of the Hungarian fertile age population struggles with reproductivity problems. Previous researches have shown that psychological well-being and lifestyle factors play a pivotal role in overall health status, which is closely related to fertility. The aim of the study was to examine fertility-related psychological and lifestyle factors in a Hungarian sample. 194 women (115 infertile and 79 fertile) took part in the study. Standardized, validated questionnaires were used for the assessment of psychological factors and self-administered questions were used for exploring lifestyle factors. The results show that infertile women are younger (33.98±4.89 vs. 36.43±5.81 years, p<0.005) and their psychological status is significantly worse compared to their fertile counterparts. The number of their depressive (BDI 14.00±12.21 vs. 7.79±9.17, p<0.005) and anxiety symptoms is higher (STAI-T 48.53±10.56 vs. 40.25±10.65, p<0.005) compared to fertile women. Findings related to lifestyle factors show that lower level of fluid consumption (1.71±0.67 vs. 1.95±0.68, p<0.05) and diet (31.30% vs. 18.42%, p<0.05) is significantly related to infertility. In this sample higher level of fluid consumption was associated with the fertile group (OR = 1.65, CI = 2.58-1.06), independently of body mass index and age. The results confirm the findings of international researches showing that women struggling with infertility are in worse psychological condition than their fertile counterparts. The authors conclude that the findings demand further investigations and follow-up studies in order to more specifically determine the relationship between fluid consumption and fertility.

  1. Temperature and rainfall are related to fertility rate after spring artificial insemination in small ruminants

    NASA Astrophysics Data System (ADS)

    Abecia, J. A.; Arrébola, F.; Macías, A.; Laviña, A.; González-Casquet, O.; Benítez, F.; Palacios, C.

    2016-10-01

    A total number of 1092 artificial inseminations (AIs) performed from March to May were documented over four consecutive years on 10 Payoya goat farms (36° N) and 19,392 AIs on 102 Rasa Aragonesa sheep farms (41° N) over 10 years. Mean, maximum, and minimum ambient temperatures, mean relative humidity, mean solar radiation, and total rainfall on each insemination day were recorded. Overall, fertility rates were 58 % in goats and 45 % in sheep. The fertility rates of the highest and lowest deciles of each of the meteorological variables indicated that temperature and rainfall had a significant effect on fertility in goats. Specifically, inseminations that were performed when mean (68 %), maximum (68 %), and minimum (66 %) temperatures were in the highest decile, and rainfall was in the lowest decile (59 %), had a significantly ( P < 0.0001) higher proportion of does that became pregnant than did the ewes in the lowest decile (56, 54, 58, and 49 %, respectively). In sheep, the fertility rates of the highest decile of mean (62 %), maximum (62 %), and minimum (52 %) temperature, RH (52 %), THI (53 %), and rainfall (45 %) were significantly higher ( P < 0.0001) than were the fertility rates among ewes in the lowest decile (46, 45, 45, 45, 46, and 43 %, respectively). In conclusion, weather was related to fertility in small ruminants after AI in spring. It remains to be determined whether scheduling the dates of insemination based on forecasted temperatures can improve the success of AI in goats and sheep.

  2. Short- and long-term effects of unemployment on fertility

    PubMed Central

    Currie, Janet; Schwandt, Hannes

    2014-01-01

    Scholars have been examining the relationship between fertility and unemployment for more than a century. Most studies find that fertility falls with unemployment in the short run, but it is not known whether these negative effects persist, because women simply may postpone childbearing to better economic times. Using more than 140 million US birth records for the period 1975–2010, we analyze both the short- and long-run effects of unemployment on fertility. We follow fixed cohorts of US-born women defined by their own state and year of birth, and relate their fertility to the unemployment rate experienced by each cohort at different ages. We focus on conceptions that result in a live birth. We find that women in their early 20s are most affected by high unemployment rates in the short run and that the negative effects on fertility grow over time. A one percentage point increase in the average unemployment rate experienced between the ages of 20 and 24 reduces the short-run fertility of women in this age range by six conceptions per 1,000 women. When we follow these women to age 40, we find that a one percentage point increase in the unemployment rate experienced at ages 20–24 leads to an overall loss of 14.2 conceptions. This long-run effect is driven largely by women who remain childless and thus do not have either first births or higher-order births. PMID:25267622

  3. Historical Agricultural Nitrogen Fertilizer Management in the Contiguous United States during 1850-2015.

    NASA Astrophysics Data System (ADS)

    Lu, C.; Cao, P.; Yu, Z.

    2017-12-01

    The United States has a century-long history of managing anthropogenic nitrogen (N) fertilizer to booster the crop production. Accurate characterization of N fertilizer use history could provide essential implications for N use efficiency (NUE) enhancement and N loss reduction. However, a spatially explicit time-series data remains lacking to describe how N fertilizer use varied among crop types, regions, and time periods. In this study, we therefore developed long-term gridded N management maps depicting N fertilizer application rate, timing, and ratio of fertilizer forms in nine major crops (i.e. corn, soybean, winter wheat, spring wheat, cotton, sorghum, rice, barley, and durum wheat) in the contiguous U.S. at a resolution of 1 km × 1 km during 1850-2015. We found that N application rates of the U.S. increased by approximately 34 times since 1940. Nonetheless, spatial analysis revealed that N-use hotspots have shifted from the West and Southeast to the Midwest and the Great Plains since 1900. Specifically, corn of the Corn Belt region received the most intensive N input in spring, followed by large N application amount in fall, implying a high N loss risk in this region. Moreover, spatiotemporal patterns of NH4+/NO3- ratio varied largely among regions. Generally, farmers have increasingly favored NH4+-form fertilizers over NO3- fertilizers since the 1940s. The N fertilizer use data developed in this study could serve as an essential input for modeling communities to fully assess the N addition impacts, and improve N management to alleviate environmental problems.

  4. Levels and associations among self-esteem, fertility distress, coping, and reaction to potentially being a genetic carrier in women with diminished ovarian reserve.

    PubMed

    Cizmeli, Ceylan; Lobel, Marci; Franasiak, Jason; Pastore, Lisa M

    2013-06-01

    To measure the level of distress and its relationship with other psychologic factors in women with diminished ovarian reserve (DOR) who participated in a fragile X genetics study. Longitudinal data analyzed with structural equation modeling. Four U.S. private and academic fertility centers. Sixty-two infertile patients with DOR. None. Fertility Problem Inventory, Coping Scale for Infertile Couples, Rosenberg Self-Esteem, Health Orientation Scale. Nineteen percent had low fertility distress, 56% had average fertility distress, and 24% had high fertility distress. Thirty-six percent self-reported a "favorable" or "very favorable" emotional response to potentially being a fragile X carrier (termed "emotions"), 53% were "ambivalent," and 11% had an unfavorable reaction. Three months after learning that they were not a carrier, these percentages were 91%, 9%, and 0%, respectively. Emotions at this second time point were significantly more positive than at pretesting. At baseline, higher self-esteem was a significant predictor of reduced fertility distress both directly and indirectly through emotions. Fertility distress was not associated with coping. Self-esteem, fertility distress, pretesting emotions, and coping were unrelated to posttesting emotions. The potential of having an explanation for one's DOR condition may have a beneficial impact on women's psychologic states during the process of genetic testing, and this appeared to be especially true for women with higher self-esteem. Psychologic interventions targeted to women with low self-esteem may reduce distress and improve reactions to genetic testing. Copyright © 2013 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  5. Effect of N Fertilization Pattern on Rice Yield, N Use Efficiency and Fertilizer–N Fate in the Yangtze River Basin, China

    PubMed Central

    Liu, Xiaowei; Wang, Huoyan; Zhou, Jianmin; Hu, Fengqin; Zhu, Dejin; Chen, Zhaoming; Liu, Yongzhe

    2016-01-01

    High N loss and low N use efficiency (NUE), caused by high N fertilizer inputs and inappropriate fertilization patterns, have become important issues in the rice (Oryza sativa L.) growing regions of southern China. Changing current farmer fertilizer practice (FFP, 225 kg ha–1 N as three applications, 40% as basal fertilizer, 30% as tillering fertilizer and 30% as jointing fertilizer) to one—time root—zone fertilization (RZF, 225 kg ha–1 N applied once into 10 cm deep holes positioned 5 cm from the rice root as basal fertilizer) will address this problem. A two—year field experiment covering two rice growing regions was conducted to investigate the effect of urea one—time RZF on rice growth, nutrient uptake, and NUE. The highest NH4+–N content for RZF at fertilizer point at 30 d and 60 d after fertilization were 861.8 and 369.9 mg kg–1 higher than FFP, respectively. Rice yield and total N accumulation of RZF increased by 4.3–44.9% and 12.7–111.2% compared to FFP, respectively. RZF reduced fertilizer—N loss by 56.3–81.9% compared to FFP. The NUEs following RZF (mean of 65.8% for the difference method and 43.7% for the labelled method) were significantly higher than FFP (mean of 35.7% for the difference method and 14.4% for the labelled method). In conclusion, RZF maintained substantial levels of fertilizer—N in the root—zone, which led to enhanced rice biomass and N uptake during the early growth stages, increased fertilizer—N residual levels and reduced fertilizer—N loss at harvest. RZF produced a higher yield increment and showed an increased capacity to resist environmental threats than FFP in sandy soils. Therefore, adopting suitable fertilizer patterns plays a key role in enhancing agricultural benefits. PMID:27861491

  6. Potential health consequences of ground-water contamination by nitrates in Nebraska.

    PubMed

    Weisenburger, D D

    1993-01-01

    Ground water serves as the primary source of drinking water for nearly all of rural Nebraska. However, ground-water contamination by nitrates, largely due to the use of fertilizers, is an increasing problem. In an ecologic study, the author found that counties characterized by high fertilizer usage and significant ground-water contamination by nitrates also had a high incidence of non-Hodgkin's lymphoma. Other potential health effects of nitrates in drinking water are also discussed.

  7. Nitrate and Nitrogen Oxides: Sources, Health Effects and Their Remediation.

    PubMed

    Hakeem, Khalid Rehman; Sabir, Muhammad; Ozturk, Munir; Akhtar, Mohd Sayeed; Ibrahim, Faridah Hanum

    Increased use of nitrogenous (N) fertilizers in agriculture has significantly altered the global N-cycle because they release nitrogenous gases of environmental concerns. The emission of nitrous oxide (N 2 O) contributes to the global greenhouse gas accumulation and the stratospheric ozone depletion. In addition, it causes nitrate leaching problem deteriorating ground water quality. The nitrate toxicity has been reported in a number of studies showing the health hazards like methemoglobinemia in infants and is a potent cause of cancer. Despite these evident negative environmental as well as health impacts, consumption of N fertilizer cannot be reduced in view of the food security for the teeming growing world population. Various agronomic and genetic modifications have been practiced to tackle this problem. Some agronomic techniques adopted include split application of N, use of slow-release fertilizers, nitrification inhibitors and encouraging the use of organic manure over chemical fertilizers. As a matter of fact, the use of chemical means to remediate nitrate from the environment is very difficult and costly. Particularly, removal of nitrate from water is difficult task because it is chemically non-reactive in dilute aqueous solutions. Hence, the use of biological means for nitrate remediation offers a promising strategy to minimize the ill effects of nitrates and nitrites. One of the important goals to reduce N-fertilizer application can be effectively achieved by choosing N-efficient genotypes. This will ensure the optimum uptake of applied N in a balanced manner and exploring the molecular mechanisms for their uptake as well as metabolism in assimilatory pathways. The objectives of this paper are to evaluate the interrelations which exist in the terrestrial ecosystems between the plant type and characteristics of nutrient uptake and analyze the global consumption and demand for fertilizer nitrogen in relation to cereal production, evaluate the various methods used to determine nitrogen use efficincy (NUE), determine NUE for the major cereals grown across large agroclimatic regions, determine the key factors that control NUE, and finally analyze various strategies available to improve the use efficiency of fertilizer nitrogen.

  8. Anxiety and depression among infertile women: a cross-sectional survey from Hungary.

    PubMed

    Lakatos, Enikő; Szigeti, Judit F; Ujma, Péter P; Sexty, Réka; Balog, Piroska

    2017-07-24

    Infertility is often associated with a chronic state of stress which may manifest itself in anxiety-related and depressive symptoms. The aim of our study is to assess the psychological state of women with and without fertility problems, and to investigate the background factors of anxiety-related and depressive symptoms in women struggling with infertility. Our study was conducted with the participation of 225 (134 primary infertile and 91 fertile) women, recruited in a clinical setting and online. We used the following questionnaires: Spielberger Trait Anxiety Inventory (STAI-T), Shortened Beck Depression Inventory (BDI) and Fertility Problem Inventory (FPI). We also interviewed our subjects on the presence of other sources of stress (the quality of the relationship with their mother, financial and illness-related stress), and we described sociodemographic and fertility-specific characteristics. We tested our hypotheses using independent-samples t-tests (M ± SD) and multiple linear regression modelling (ß). Infertile women were younger (33.30 ± 4.85 vs. 35.74 ± 5.73, p = .001), but had significantly worse psychological well-being (BDI = 14.94 ± 12.90 vs. 8.95 ± 10.49, p < .0001; STAI-T = 48.76 ± 10.96 vs. 41.18 ± 11.26, p < .0001) than fertile subjects. Depressive symptoms and anxiety in infertile women were associated with age, social concern, sexual concern and maternal relationship stress. Trait anxiety was also associated with financial stress. Our model was able to account for 58% of the variance of depressive symptoms and 62% of the variance of trait anxiety. Depressive and anxiety-related symptoms of infertile women are more prominent than those of fertile females. The measurement of these indicators and the mitigation of underlying distress by adequate psychosocial interventions should be encouraged.

  9. Marriage and fertility in the developed countries.

    PubMed

    Westoff, C F

    1978-12-01

    Most developed countries have reached zero population growth or less and, while population projections have often proved badly off-target, it seems that currently low fertility levels are the result of a long-term trend, which was interrupted in the last 100 years only by the still-unexplained postwar baby boom, and which will probably continue. The declining trend has accompanied economic development and modernization, which have transformed the economic value of children, making them a drain on resources rather than a source of income. The concomitant social changes seem largely irreversible: urban economy, the decline in traditional authority, universal, prolonged education, equality of women, low infant mortality, high consumer demands and sophisticated birth control technology are all here to stay. The theory that fertility exhibits a cyclical pattern based on people's perception of their degree of economic and social opportunity ignores the other elements affecting fertility behavior, especially the radical change in the status and expectations of women. Several trends in marriage and reproductive behavior in the U.S., Denmark and Sweden reinforce the presumption that fertility will remain low: declining number of marriages; postponement of marriage; increased tendency for unmarried couples to live together; instability of marriage shown by high divorce rates and declining remarriage rates; and increasing economic activity by women. The traditional institution of marriage is losing its economic, sexual, sociological and parenting rationales. Thus, declining fertility is both cause and consequence of changes in marriage. In Europe, where the decline is more advanced than in the U.S., governments are concerned that population growth will be too low and have instituted social welfare measures to induce and facilitate childbearing and childrearing. As women become more career-oriented, greater incentives will have to be provided. Manipulating immigration quotas may solve the short-term numbers problem but creates other social problems. Serious thought must be given to the effects of negative population growth.

  10. China's Population Policy at the Crossroads: Social Impacts and Prospects

    PubMed Central

    Jiang, Quanbao; Li, Shuzhuo; Feldman, Marcus W.

    2015-01-01

    China's total fertility rate fell below replacement level in the 1990s. From the 1970s the fertility rate declined dramatically, mainly as a consequence of the national population policy whose aim has been to limit birth numbers, control population growth and boost economic growth. Having achieved such a low fertility rate, how will China's population policy evolve in the future? This paper first reviews the history of China's population policy since 1970 in terms of three stages: 1970-1979; 1980-1999; and after 2000. We explore the impacts of China's population policy, including relief of pressure on China's environment and resources, fertility decline, the unexpectedly high male-biased sex ratio at birth (SRB), the coming shortage of labor force, and the rapid aging of the population. We also investigate ethical issues raised by the implementation of the policy and its results. Finally we introduce the controversy over potential adjustment of the policy, acknowledging the problems faced by western countries with low fertility and countermeasures they have taken. We offer some suggestions that might be appropriate in the Chinese context. PMID:26612983

  11. Fertilization effects on the electrical conductivity measured by EMI, ERT, and GPR

    NASA Astrophysics Data System (ADS)

    Weihermueller, L.; Kaufmann, M.; Steinberger, P.; Pätzold, S.; Vereecken, H.; Van Der Kruk, J.

    2017-12-01

    Near surface geophysics such as electromagnetic induction (EMI), electrical resistivity tomography (ERT), and ground penetrating radar (GPR) are widely used for field characterization, to delineate soil units, and to estimate soil texture, bulk densities and/or soil water contents. Hereby, the measured soil apparent conductivity (ECa) is often used. Soil ECa is governed by horizontal and vertical changes in soil texture, mineralogy, soil water content, and temperature, and the single contributions are not easy to disentangle. Within single fields and between fields fertilization management may vary spatially, which holds especially for field trials. As a result, ECa might vary due to differences in electrolyte concentration and subsequent pore fluid conductivity, but secondary fertilization effects might also play a major role in ECa differences such as differences in soil water uptake by growing plants. To study the direct effect of mineral fertilization on ECa, a field experiment was performed on 21 bare soil plots each of a size of 9 m2, where 7 different fertilization treatments were established in triplicates. As mineral fertilizers, commercial calcium ammonium nitrate and potassium chloride were chosen and applied in dosages of 200, 400, and 2000 kg ha-1 N equivalent. Additionally, soil water, soil temperature, and EC were recorded in a pit at different depths using commercial sensors. Changes in ECa were measured every 10 days using EMI and monthly using GPR and ERT. Additionally, soil samples were monthly taken at all plots and nitrate, chloride, and potassium contents were measured in the lab. The poster will show the effect of ECa changes due to fertilization and corresponding leaching of the fertilized elements over time. The experimental results provide information of how fertilization is influencing ECa readings and how long the fertilizers are influencing ECa measurements with geophysical instruments. This study helps to overcome restricted interpretation of ECa measurements on managed agricultural soils.

  12. Teaching Basic Science Environmentally. Concept: Plants Reproduce Their Own Kind.

    ERIC Educational Resources Information Center

    Busch, Phyllis

    1987-01-01

    Offers suggestions for spring activities focusing on plant reproduction both indoors and outdoors. Suggests planting seeds to observe, measure, and record effects of temperature, moisture, fertilizer. Recommends outdoor study of the horsetail plant. (NEC)

  13. Do children make you happier? Sustained child-wish and mental health in women 11-17 years after fertility treatment.

    PubMed

    Gameiro, Sofia; van den Belt-Dusebout, Alexandra W; Bleiker, Eveline; Braat, Didi; van Leeuwen, Flora E; Verhaak, Christianne M

    2014-10-10

    Are fertility treatment-related factors, parenthood status and sustained child-wish associated with women's long-term mental health? Sustaining a child-wish is more strongly associated with women's long-term mental health than fertility treatment-related factors and parenthood status. About one-third of the couples starting fertility treatment do not achieve parenthood and have to adjust to an unfulfilled child-wish. In women, remaining childless after treatment is associated with less favourable mental health. It is unclear if this is only related to their childlessness or if adjustment after unsuccessful treatment is affected by other variables. These include diagnostic and treatment-related factors (cause of fertility problems, age at first consultation, type and number of treatments) and the psychological ability to come to terms with the unfulfilled child-wish. Differentiating the relative contribution of these factors to women's long-term mental health will provide useful knowledge to support patients adjusting to negative treatment outcomes. A cross-sectional study with a nationally representative sample of 7148 women who started fertility treatment at any of the 12 IVF hospitals in the Netherlands from 1995 through 2000. Of 16 482 women who were invited to participate, 7148 (43.4%) provided psychological data. The average age of women was 47 years and the average age at first fertility consultation was 30 years. Fifty-one per cent of women did IUI and 85% did IVF/ICSI. Ninety per cent of women were married/cohabiting, 20.9% remained childless and 5.9% had a child-wish. Women completed a questionnaire assessing diagnostic and treatment factors (retrospective data), parenthood status, sustained child-wish and mental health. A multiple regression analysis controlling for background variables showed that, first, male factor (P < 0.05) and/or idiopathic infertility (P < 0.001) were associated with better mental health. Secondly, starting fertility treatment at an older age was associated with better mental health (P < 0.01). Thirdly, the interaction between parenthood status and sustained child-wish was significant (P < 0.01). Having a child-wish was associated with worse mental health for women with (β = -0.058, P < 0.01) and without children (β =-0.136, P < 0.001), but associations were stronger for the latter. Predictive factors accounted for <5% of the variation in mental health status in the study population. The sample was large and nationally representative. Response rate was in line with other studies but women without psychological data were less likely to have biological children and 15.9% of non-responders considered the questionnaire to be too confronting or to elicit too emotional memories. This could reflect an underestimation of the proportion of women with a sustained child-wish. Sustaining a child-wish is a more important risk for long-term adjustment problems than parenthood status. Women adjust better when they start treatment at older ages and know they were not responsible for the cause of the fertility problem. Fertility staff can play an important role in preparing patients for the possibility of treatment failure and the associated grief process. They can also inform patients about the positive effect of refocusing their life goals. This study was supported by a grant from the Dutch Cancer Society (2006-3631). No competing interests exist. N/A. © The Author 2014. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  14. Effects of different nitrogen reduction modes on yield of spring maize and nitrate - N residue in soils of the southern Loess Plateau

    NASA Astrophysics Data System (ADS)

    Dang, Tinghui; Dong, Qiang

    2017-04-01

    【Objectives】Excessive fertilization in farmland caused nitrate leaching and accumulation in soil, which not only reduced the fertilizer utilization rate, but also had potential environmental problems. The effects of different nitrogen reduction modes on yield of spring maize and soil NO3-N in the southern Loess Plateau were discussed, and scientific fertilization suggestions were put forward, which were of great significance to instruct local maize fertilization and protect environment safety. 【Methods】A field experiment was conducted in the south of the Loess Plateau for three years. Spring maize was planted with half plastic film mulching in one crop per annum.The experiment consisted of 5 N fertilization treatments: control treatment (CK),conventional N fertilization rate (Con), optimal N fertilizationⅠ(OptⅠ), optimal N fertilizationⅡ (Opt Ⅱ) and optimal N fertilization Ⅲ(Opt Ⅲ), The changes of yield of maize, nitrogen uptake and soil NO3-N were measured.【Results】The results showed that, compared with the conventional fertilization, the grain yield and N uptake of maize had no significant change under the three optimal N fertilization application models, the rate of the grain yield's change is 100 300kg/hm2. Compared with the conventional fertilization, agronomic efficiency of fertilizer-nitrogen and N partial fertilizer productivity were increased by 20.2% 23.2% and 21.9% 23.7%, respectively. The accumulation of nitrate nitrogen in profile (0-200 cm) decreased by 90.7 kg / hm2, 97.3 kg / hm2, 100.7 kg / hm2 ,respectively, with the decreases of 44.7%, 47.9% and 49.6% respectively.【Conclusions】The optimum nitrogen fertilization pattern did not affect spring maize yield and N uptake, and could improve agronomic efficiency of fertilizer-nitrogen and N partial fertilizer productivity. Under the same nitrogen application rate, the effects of adding nitrification inhibitor or slow-release fertilizer on nitrate-N residue were not obvious. The amount of nitrogen applied, the mode and type of fertilization had a certain effect on the migration of nitrate nitrogen. Optimized N - application model could significantly reduce the NO3—N residue in soil profile. It is suggested to reduce the amount of nitrogen fertilizer by 20% on the basis of the traditional nitrogen fertilizer when the spring maize is planted with half plastic film mulching, which can guarantee the yield and protect the environment.

  15. An analysis of social consequences of rapid fertility decline in China.

    PubMed

    Liu, Z; Liu, L

    1988-12-01

    Rapid fertility decline in China has brought about 2 direct effects: 1) the natural increase of the population has slowed down, and 2) the age structure has changed from the young to the adult type. These 2 effects have caused a series of economic and social consequences. Rapid fertility decline increases the gross national product per capita and accelerates the improvement of people's lives. Rapid fertility decline slows population growth and speeds up the accumulation of capital and the development of the economy. Since 1981, accumulation growth has exceeded consumption growth. Fertility decline alleviates the enrollment pressure on primary and secondary schools, raises the efficiency of education funds, and promotes the popularization of education. The family planning program strengthens the maternal and child health care and the medical care systems. As the result of economic development, the people's nutritional levels are improving. The physical quality of teenagers has improved steadily. The change in the age structure will alleviate the tension of rapid population growth and benefit population control in the next century. Fertility decline forces the traditional attitude toward childbearing from "more children, more happiness" to improved quality of children. The rapid fertility decline has caused a great deal of concern both inside and outside China about the aging of the population. The labor force, however, will continue to grow for the next 60 years. At present, China's population problems are still those of population growth.

  16. Determination of chromium (VI) in primary and secondary fertilizer and their respective precursors.

    PubMed

    Krüger, Oliver; Fiedler, Francesca; Adam, Christian; Vogel, Christian; Senz, Rainer

    2017-09-01

    Hexavalent chromium species (Cr(VI)) are often carcinogenic, of high acute toxicity, highly mobile, and thus pose a severe risk to health and environment. Fertilizers usually contain significant amounts of chromium. Therefore, a reliable analysis of chromium and the fraction of Cr(VI) are crucial for safe use of fertilizers. This problem is expected to increase in the future, since more and more recycled fertilizers emerge due to increasing fertilizer demand and respective supply risks. However, existing analytical methods have been developed for conventional fertilizers and have to be tested whether they are suitable for the new materials. Thus, we performed a wet-chemical extraction for Cr(VI) on several matrices as well as respective quality control experiments including spiking with Cr(III) and Cr(VI) compounds. We found the Cr(VI) amounts to be below 2 mg/kg except for a thermally post-treated sewage sludge ash (SSA) that showed 12.3 mg/kg. The presence of organic matter e.g. in sludge or precipitated struvite caused a reduction of spiked Cr(VI) and thus no satisfying recovery for quality control. Cr(VI) reduction was also observed for SSA, presumably due to the presence of Fe(II) compounds. Even though the tested procedure can be hampered in some recycled fertilizer matrices, it might be adapted to be applicable also for these complex samples. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Use of fertility drugs and risk of ovarian cancer: Danish Population Based Cohort Study.

    PubMed

    Jensen, Allan; Sharif, Heidi; Frederiksen, Kirsten; Kjaer, Susanne Krüger

    2009-02-05

    To examine the effects of fertility drugs on overall risk of ovarian cancer using data from a large cohort of infertile women. Population based cohort study. Danish hospitals and private fertility clinics. 54,362 women with infertility problems referred to all Danish fertility clinics during 1963-98. The median age at first evaluation of infertility was 30 years (range 16-55 years), and the median age at the end of follow-up was 47 (range 18-81) years. Included in the analysis were 156 women with invasive epithelial ovarian cancer (cases) and 1241 subcohort members identified in the cohort during follow-up in 2006. Effect of four groups of fertility drugs (gonadotrophins, clomifene citrate, human chorionic gonadotrophin, and gonadotrophin releasing hormone) on overall risk of ovarian cancer after adjustment for potential confounding factors. Analyses within cohort showed no overall increased risk of ovarian cancer after any use of gonadotrophins (rate ratio 0.83, 95% confidence interval 0.50 to 1.37), clomifene (1.14, 0.79 to 1.64), human chorionic gonadotrophin (0.89, 0.62 to 1.29), or gonadotrophin releasing hormone (0.80, 0.42 to 1.51). Furthermore, no associations were found between all four groups of fertility drugs and number of cycles of use, length of follow-up, or parity. No convincing association was found between use of fertility drugs and risk of ovarian cancer.

  18. Optimal birth control of age-dependent competitive species III. Overtaking problem

    NASA Astrophysics Data System (ADS)

    He, Ze-Rong; Cheng, Ji-Shu; Zhang, Chun-Guo

    2008-01-01

    A study is made of an overtaking optimal problem for a population system consisting of two competing species, which is controlled by fertilities. The existence of optimal policy is proved and a maximum principle is carefully derived under less restrictive conditions. Weak and strong turnpike properties of optimal trajectories are established.

  19. [Biomedical Perspective of the Surrogate Motherhood].

    PubMed

    Jouve de la Barreda, Nicolás

    2017-01-01

    The subrogated motherhood takes place when an embryo created by in vitro fertilization (IVF) technology is implanted in a surrogate, sometimes called a gestational mother, by means a contract with her. It can imply to natural families (woman and man) with or without infertility problems, or to monoparental or biparental families of the same sex. Concerning the origin of the gametes used in the IVF emerges different implications on the genetic relationship of the resulting child with the surrogate and the future parents. The subrogated motherhood was initially considered an option to solve infertility problems. Nevertheless this practice has become a possible and attractive option as a source of economic resources for poor women. The cases of benefit of a pregnancy without mediating a contract are exceptional and they are not properly cases of ″subrogated maternity″ but of ″altruistic maternity″ and must be considered as heterologous in vitro fertilization. In this article are analyzed the medical, genetic and bioethics aspects of this new derivation of the fertilization in vitro. As points of special attention are considered the following questions: Is it the surrogate motherhood used preferably to solve infertility problems? Is not this actually a new form of exploitation of the woman? Does not suppose an attack to the natural family? Does not suppose in addition an attack to the dignity of the human being?

  20. Cancer and fertility preservation in Puerto Rico: a qualitative study of healthcare provider perceptions.

    PubMed

    Dyer, Karen E; Quinn, Gwendolyn P

    2016-08-01

    This study aims to examine healthcare provider perceptions of cancer-related infertility and fertility preservation (FP) in an underserved population and to highlight cognitive and structural barriers to use. In-depth, semi-structured interviews were conducted with a sample of 16 healthcare providers participating in a larger ethnographic study on cancer survivorship and cancer-related infertility in Puerto Rico, an unincorporated US territory. Interviews were conducted in-person, audio-recorded, transcribed verbatim, and coded using the constant comparative method. Providers identified several barriers to FP in Puerto Rico: high cost in relation to income levels, lack of insurance coverage, gaps in provider knowledge of fertility clinics and financial assistance, lower prioritization of quality-of-life needs leading to inconsistent physician disclosure of fertility risks, geographical location of fertility clinics, and logistical challenges to maintaining FP offerings. Two factors act as facilitators: a high value placed on patient-provider communication and relationships and the formation of local alliances between the oncology and reproductive medicine fields, potentially leading to increased cross-specialty communication and referral. Infertility is a continuing source of distress for cancer patients and survivors, and barriers to FP vary cross-culturally. In Puerto Rico, context-specific factors indicate potential areas of intervention. Greater awareness of fertility risks and options can be fostered through physician training in conjunction with organizational measures targeting cost barriers.

  1. Maternal Risk of Breeding Failure Remained Low throughout the Demographic Transitions in Fertility and Age at First Reproduction in Finland

    PubMed Central

    Liu, Jianghua; Rotkirch, Anna; Lummaa, Virpi

    2012-01-01

    Radical declines in fertility and postponement of first reproduction during the recent human demographic transitions have posed a challenge to interpreting human behaviour in evolutionary terms. This challenge has stemmed from insufficient evolutionary insight into individual reproductive decision-making and the rarity of datasets recording individual long-term reproductive success throughout the transitions. We use such data from about 2,000 Finnish mothers (first births: 1880s to 1970s) to show that changes in the maternal risk of breeding failure (no offspring raised to adulthood) underlay shifts in both fertility and first reproduction. With steady improvements in offspring survival, the expected fertility required to satisfy a low risk of breeding failure became lower and observed maternal fertility subsequently declined through an earlier age at last reproduction. Postponement of the age at first reproduction began when this risk approximated zero–even for mothers starting reproduction late. Interestingly, despite vastly differing fertility rates at different stages of the transitions, the number of offspring successfully raised to breeding per mother remained relatively constant over the period. Our results stress the importance of assessing the long-term success of reproductive strategies by including measures of offspring quality and suggest that avoidance of breeding failure may explain several key features of recent life-history shifts in industrialized societies. PMID:22529952

  2. Effective Phytoextraction of Cadmium (Cd) with Increasing Concentration of Total Phenolics and Free Proline in Cannabis sativa (L) Plant Under Various Treatments of Fertilizers, Plant Growth Regulators and Sodium Salt.

    PubMed

    Ahmad, Ayaz; Hadi, Fazal; Ali, Nasir

    2015-01-01

    The comparative effect of fertilizers (NPK), plant growth regulators (GA3, IAA, Zeatin) and sodium chloride (NaCl) on Cd phytoaccumulation, proline and phenolics production in Cannabis sativa was evaluated. Proline and phenolices were correlated with Cd contents in plant. Cd significantly reduced the plant growth. Fertilizers application (in combination) most significantly increased the growth (19 cm root and 47 cm shoot) on Cd contaminated soil. All treatments increased the Cd contents in plant tissues. This increase was highly significant in fertilizers treated plants (1101, 121 and 544 ppm in roots, stem and leaves respectively). Significantly positive correlation was found between Cd concentration and dry biomass of root (R2=0.7511) and leaves (R2=0.5524). All treatments significantly increased the proline and total phenolics and maximum was recorded in NaCl treated plants followed by fertilizers. Proline was higher in roots while phenolics in leaves. The correlation between proline and phenolics was positive in leaf (R2=0.8439) and root (R2=0.5191). Proline and phenolics showed positive correlation with Cd concentration in plant. Conclusively, fertilizers in combination seem to be the better option for Cd phytoextraction. Further investigation is suggested to study the role of phenolics and proline in Cd phytoextraction.

  3. Evaluation of Fertilizer Potential of Different K Compounds Prepared Utilizing Sea Bittern as Feed Stock

    PubMed Central

    Trivedi, Khanjan; Kubavat, Denish; Ghara, Krishna K.; Kumar, Ranjeet; Trivedi, Hardik; Anand, K. G. Vijay; Maiti, Pratyush; Ghosh, Arup

    2017-01-01

    Aim: Many countries import potassic fertilizers due to dearth of K-mineral deposits. Therefore processes to obtain K-nutrient sources from sea bittern were developed by our Institute. The present investigation evaluated the fertilizer potential of three different sea bittern-derived (SBD) potassium forms developed viz., potassium schoenite, potassium nitrate and potassium ammonium sulfate on maize productivity in two cropping seasons. Methods: The pot and field experiments consisted of four treatments, wherein the three K forms were applied at the recommended rate of 40 kg K2O ha−1 and were compared with commercially used sulfate of potash. The effect of these fertilizers on different parameters of plant and soil were evaluated. Results: The application of SBD-potassic fertilizers led to enhancement in growth, productivity and quality of maize which related well with higher photosynthesis, nutrient uptake and soil quality parameters. On an average all the three forms of sea bittern-derived potash enhanced yield of maize over control by 22.3 and 23.8%, respectively, in pot and field trials. The best performance was under SBD-KNO3, which also recorded the highest benefit: cost ratio of 1.76. Conclusion: The K-fertilizers derived from sea-bittern—a waste product of salt industry—can thus be economically used to improve crop production sustainably. PMID:28936217

  4. Varicocele

    MedlinePlus

    ... the scrotum Possible problems with fertility or decreased sperm count Some men do not have symptoms. Exams ... of your testicle. If you have surgery, your sperm count will likely increase. However, it will not ...

  5. Cystic echinococcosis in cattle slaughtered at Shashemanne Municipal Abattoir, south central Oromia, Ethiopia: prevalence, cyst distribution and fertility.

    PubMed

    Negash, Kedir; Beyene, Desta; Kumsa, Bersissa

    2013-04-01

    Cystic echinococcosis is one of the most widespread zoonoses, causing morbidity and mortality in humans and huge economic losses in livestock. It is caused by metacestodes of the tapeworm Echinococcus granulosus. The metacestodes cause hydatid cysts in the lungs, liver and other organs of intermediate hosts. A study was made from December 2010 through March 2011 to determine the prevalence, organ distribution and characteristics of hydatid cysts in cattle slaughtered at Shashemanne Municipal Abattoir in Oromia, Ethiopia. Antemortem examination of 384 cattle was followed by standard postmortem inspection of their internal organs including lungs, liver, kidneys, spleen and heart for the presence of hydatid cysts. The overall prevalence of hydatid cysts recorded in cattle slaughtered at Shashemanne Municipal Abattoir was 49.5% (190/384). Hydatid cyst prevalence was significantly higher in cattle more than 7 years old compared with those aged 7 years or less, in male cattle compared with female cattle (51.9% vs 31.9%), and in cattle with a body condition score of lean or medium rather than fat (54.05% and 83.2% vs 22.9%). The greatest proportions of cysts were recorded in the lungs (71.6%) and liver (24.1%). Lungs and liver were more commonly infected (95.5%) than other organs. Of the cysts recorded, 15.9% were fertile, 71.7% sterile and 12.2% calcified. The percentage of fertile cysts in the lungs was higher than that in any other organ. Our study showed widespread occurrence of cystic echinococcosis in cattle, which may have a role in the lifecycle of this serious zoonosis.

  6. Fertilization capacity of cryopreserved Iberian ibex epididymal sperm in a heterologous in vitro fertilization assay.

    PubMed

    López-Saucedo, J; Santiago-Moreno, J; Fierro, R; Izquierdo, D; Coloma, M A; Catalá, M G; Jiménez, I; Paramio, M T

    2015-02-01

    In vitro fertilization (IVF) can be used to assess the fertilization capacity of sperm. Heterologous IVF may be useful when assessing that of wild animals as it is often difficult to obtain adequate numbers of naturally corresponding oocytes. The aim of the present study was to assess the fertilization capacity of frozen-thawed ibex epididymal spermatozoa via heterologous IVF involving the oocytes of prepubertal domestic goats. The effect on fertilization and embryo development of adding oestrous sheep serum (ESS) to the fertilization medium was also examined. Cumulus-oocyte complexes (COCs) were matured in TCM-199 for 24-27 h at 38.5°C in a 5% CO2 in air atmosphere. Frozen-thawed epididymal spermatozoa were selected by density gradient centrifugation. After maturation, the oocytes were co-incubated with spermatozoa in synthetic oviductal fluid (SOF) with different concentrations of ESS: SOF-C (0%), SOF-2 (2%) and SOF-20 (20%). At 17 h post-insemination (hpi), zygotes with one female and one male pronucleus (2PN) were categorised as normal; zygotes with 3PN were recorded as polyspermic, and oocytes with 1PN as asynchronous. Cleavage and blastocyst development were assessed at 48 and 168 hpi respectively. The percentage of zygotes with 2PN was higher in the SOF-2 than in the SOF-20 treatment group (27.7% versus 2.9% P < 0.05). The percentage of blastocysts formed with the SOF-C, SOF-2 and SOF-20 treatments were 1.1%, 7.5% and 0% respectively. These results show that the presence of 2% ESS achieves better results than the use of no serum or the standard 20% concentration. Heterologous IVF may be an effective method for predicting the fertilization capacity of ibex spermatozoa, and therefore perhaps that of other wild mountain ungulates.

  7. Humic Fertilizer and Vermicompost Applied to the Soil Can Positively Affect Population Growth Parameters of Trichogramma brassicae (Hymenoptera: Trichogrammatidae) on Eggs of Tuta absoluta (Lepidoptera: Gelechiidae).

    PubMed

    Mohamadi, P; Razmjou, J; Naseri, B; Hassanpour, M

    2017-12-01

    The tomato leaf miner, Tuta absoluta (Meyrick), is a devastating pest of tomato worldwide. One of the control measures of T. absoluta is the use of biological control agents, such as Trichogramma wasps. Interactions between natural enemies and insect pests may be affected by application of fertilizers, because changes in plant quality through the fertilizer application may therefore affect herbivore characteristics and suitability of them to parasitism. Laboratory tests were carried out to evaluate the life table parameters of Trichogramma brassicae Bezdenko on T. absoluta eggs reared on tomato plants treated either with vermicompost (40%), humic fertilizer (2 g/kg soil), or control (suitable mixture of field soil and sand). Population growth parameters of T. brassicae were affected by fertilizer treatments. Significant differences were found for immature life period and total fecundity of T. brassicae on the treatments. Differences of intrinsic rate of natural increase (r m ), finite rate of increase (λ), net reproductive rate (R 0 ), mean generation time (T), and doubling time (DT) of T. brassicae among treatments were also significant. The lowest values of r m , λ, and R 0 were recorded for T. brassicae developed on T. absoluta eggs on control treatment, whereas the highest values of these parameters were observed on 2 g/kg humic fertilizer. Furthermore, T. brassicae had the shortest T and DT values on 2 g/kg humic fertilizer and 40% vermicompost treatments. Our results showed that application of humic fertilizer and vermicompost could positively affect population growth parameters of T. brassicae on eggs of T. absoluta fed on tomato plants.

  8. The effect of father's age in fertile, subfertile, and assisted reproductive technology pregnancies: a population based cohort study.

    PubMed

    Stern, Judy E; Luke, Barbara; Hornstein, Mark D; Cabral, Howard; Gopal, Daksha; Diop, Hafsatou; Kotelchuck, Milton

    2014-11-01

    To compare ages of mothers and of fathers at delivery in couples who are fertile, subfertile, and subfertile treated with assisted reproductive technology (ART) and to characterize birth outcomes in the ART population according to paternal age. Live birth deliveries in Massachusetts between July, 2004 and December, 2008 were identified from vital records and categorized by maternal fertility status and treatment as ART, subfertile or fertile. The ART births were linked to the Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS) database to obtain cycle-specific treatment data. Parental ages were obtained from birth certificates. Age of mothers and fathers were compared using ANOVA for continuous measures and χ (2) for categories. Risks of prematurity (<37 weeks), low birthweight (<2,500 g), and low birthweight z-score (small for gestatational age, SGA) were modeled using logistic regression by categories of paternal age as adjusted odds ratios and 95 % CI. The study population included 9,092 ART, 6,238 subfertile, and 318,816 fertile deliveries. Paternal ages in the ART and subfertile groups were similar and differed significantly from those of the fertile group. Maternal age in the ART and subfertile groups averaged 5-6 years older than their fertile counterparts and fathers averaged 4-5 years older with twice as many being older than 37. The risks for prematurity, low birthweight and SGA did not increase with increasing paternal age. Fathers in ART- treated and subfertile couples are older than in their fertile counterparts. Older paternal age was not assoicated with increased risk for prematurity, low birthweight, or SGA.

  9. Biomass of Speckled Alder on an Air-Polluted Mountain Site and its Response to Fertilization

    NASA Astrophysics Data System (ADS)

    Kuneš, Ivan; Baláš, Martin; Koňasová, Tereza; Špulák, Ondřej; Balcar, Vratislav; Millerová, Kateřina Bednářová; Kacálek, Dušan; Jakl, Michal; Zahradník, Daniel; Vítámvás, Jan; Š´astná, Jaroslava; Jaklová Dytrtová, Jana

    2014-12-01

    The article summarizes outcomes of a biomass study conducted in a young speckled alder plantation on a cold mountain site. At this location, the previously existing old forest was clear felled because of damage from air pollution, and present-day surface humus is in need of restoration. The intention of this study was to quantify the biomass and nutrients accumulated by alders and their components and assess whether the initial fertilization resulted in increased biomass production and nutrient accumulation in the biomass. Besides the control, two fertilized treatments were installed. In the surface treatment (SUT), the amendment was applied as a base dressing in small circles around trees. In the planting-hole treatment (PHT), the amendment was incorporated into soil inside the planting holes. Five growth seasons after planting and fertilization, six alders from each treatment were harvested including roots. Their biomass was quantified and analyzed for macroelements. The greatest pool of dry mass (DM) was branches in the control and stem wood in the fertilized treatments. The greatest pools of macroelements were leaves and branches. The most pronounced effects of fertilization were recorded in the DM and consequently in the absolute quantities of nutrients. The DM of an average tree in the control, SUT, and PHT was 85, 226, and 231 g, respectively. The absolute contents of nutrients per tree in the fertilized treatments showed the following increases, as compared with the control: (N) 2.5-2.6 times; (P) 1.6-2.4 times; (K) 1.8-2.1 times; and (Mg) 1.8-2.0 times, respectively. Speckled alder responded positively to fertilization.

  10. Report of the NASA Mammalian Developmental Biology Working Group

    NASA Technical Reports Server (NTRS)

    Keefe, J. R.

    1985-01-01

    Development is considered to encompass all aspects of the mammalian life span from initial initial germ cell production through the complete life cycle to death of the organism. Thus, gamete production, fertilization, embryogenesis, implantation, fetogenesis, birth, peri- and postnatal maturation, and aging were all considered as stages of a development continuum relevant to problems of Space Biology. Deliberations thus far have been limited to stages of the development cycle from fertilization to early postnatal life. The deliberations are detailed.

  11. Reconstruction of historical lead contamination and sources in Lake Hailing, Eastern China: a Pb isotope study.

    PubMed

    Zhang, Rui; Guan, Minglei; Shu, Yujie; Shen, Liya; Chen, Xixi; Zhang, Fan; Li, Tiegang; Jiang, Tingchen

    2016-05-01

    The history records of lead and its stable isotopic ratios were determined in a sediment core to receive anthropogenic impacts on the Lake Hailing in eastern China. The sediment core was dated based on (210)Pb, (137)Cs, and (239+240)Pu. The historical changes of Pb/Al and Pb isotope ratios showed increasing trend upward throughout the core, suggesting changes in energy usage and correlating closely with the experience of a rapid economic and industrial development of the catchment, Linyi City, in eastern China. Based on the mixing end member model of Pb isotope ratios, coal combustion emission dominated anthropogenic Pb sources in the half part of the century contributing 13 to 43 % of total Pb in sediment. Moreover, contributions of chemical and organic fertilizer were 1-13 and 5-14 %, respectively. In contrast, the contribution of leaded gasoline was low than 8 %. The results indicated that historical records of Pb contamination predominantly sourced from coal combustion and chemical and organic fertilizer in the catchment. In addition, an increase of coal combustion source and fertilizers was found throughout the sediment core, whereas the contribution of leaded gasoline had declined after 2000s, which is attributed to the phaseout of leaded gasoline in China.

  12. [Declining fertility with age].

    PubMed

    Lourdel, Emmanuelle; Merviel, Philippe; Cabry-Goubet, Rosalie; Brzakowski, Mélanie

    2010-06-20

    The will to be a mother at a late age has become a real problem of society for many reasons, first and foremost because of efficient birth control, long studies and second matrimonies. In front of these still young women but quite "old" for maternity, practitioners specialized in medically assisted procreation (MAP) are often helpless, specially because most of the patients think that the MAP will be able to cure the natural decline of fertility. However, MAP's procedures cannot correct the decrease of pregnancies' rates and the increase of spontaneous miscarriages linked with the age. One of the first aims of consulting-physicians should be to give patients proper advice about fertility decline, so that women could run their life, aware of these facts.

  13. Trace-element and Nd-isotope systematics in detrital apatite of the Po river catchment: Implications for provenance discrimination and the lag-time approach to detrital thermochronology

    NASA Astrophysics Data System (ADS)

    Malusà, Marco G.; Wang, Jiangang; Garzanti, Eduardo; Liu, Zhi-Chao; Villa, Igor M.; Wittmann, Hella

    2017-10-01

    Detrital thermochronology is often employed to assess the evolutionary stage of an entire orogenic belt using the lag-time approach, i.e., the difference between the cooling and depositional ages of detrital mineral grains preserved in a stratigraphic succession. The impact of different eroding sources to the final sediment sink is controlled by several factors, including the short-term erosion rate and the mineral fertility of eroded bedrock. Here, we use apatite fertility data and cosmogenic-derived erosion rates in the Po river catchment (Alps-Apennines) to calculate the expected percentage of apatite grains supplied to the modern Po delta from the major Alpine and Apenninic eroding sources. We test these predictions by using a cutting-edge dataset of trace-element and Nd-isotope signatures on 871 apatite grains from 14 modern sand samples, and we use apatite fission-track data to validate our geochemical approach to provenance discrimination. We found that apatite grains shed from different sources are geochemically distinct. Apatites from the Lepontine dome in the Central Alps show relative HREE enrichment, lower concentrations in Ce and U, and higher 147Sm/144Nd ratios compared to apatites derived from the External Massifs. Derived provenance budgets point to a dominant apatite contribution to the Po delta from the high-fertility Lepontine dome, consistent with the range independently predicted from cosmonuclide and mineral-fertility data. Our results demonstrate that the single-mineral record in the final sediment sink can be largely determined by high-fertility source rocks exposed in rapidly eroding areas within the drainage. This implies that the detrital thermochronology record may reflect processes affecting relatively small parts of the orogenic system under consideration. A reliable approach to lag-time analysis would thus benefit from an independent provenance discrimination of dated mineral grains, which may allow to proficiently reconsider many previous interpretations of detrital thermochronology datasets in terms of orogenic-wide steady state.

  14. Effect of Prenatal Exposure to Pesticides on Children's Health.

    PubMed

    Matysiak, Magdalena; Kruszewski, Marcin; Jodlowska-Jedrych, Barbara; Kapka-Skrzypczak, Lucyna

    2016-01-01

    The aim of this study was to summarize the current state of knowledge on pesticide-related fertility problems and disadventeges of childrens due to prenatal pesticides exposure. Available literature was analyzed. Due to the extent of the issue, the study focuses on epidemiological studies conducted in humans, despite evidence from in vitro and animal studies. It seems certain that exposure to harmful chemicals is one of the factors that may cause a decline in fertility and problems with conceiving, whereas exposure during pregnancy can impair foetal development. Prenatal exposure may also result in the occurrence of childhood cancer and neurobehavioral disorders. The meaning of the project is to summarize the role of pesticides in the process of reproduction. This applies especially to people working in agriculture, since they might be occupationally exposed to pesticides.

  15. Assessing infertility-related stress: the factor structure of the Fertility Problem Inventory in Italian couples undergoing infertility treatment.

    PubMed

    Donarelli, Zaira; Gullo, Salvatore; Lo Coco, Gianluca; Marino, Angelo; Scaglione, Piero; Volpes, Aldo; Allegra, Adolfo

    2015-01-01

    The factor structure of the Fertility Problem Inventory (FPI) and its invariance across gender were examined in Italian couples undergoing infertility treatment. About 1000 subjects (both partners of 500 couples) completed two questionnaires prior to commencing infertility treatment at a private Clinic in Palermo, Italy. Confirmatory Factor Analysis demonstrated that the original factor structure of the FPI was partially confirmed. Two correlated factors (Infertility Life Domains and Importance of Parenthood) were obtained via a post hoc Exploratory Factor Analysis. Finally, the invariance of this factor structure across gender was confirmed. The study supported the relevance of two interrelated factors specific to infertility stress which could help clinicians to focus on the core infertility-related stress domains of infertile couples.

  16. Malignant melanoma risk after exposure to fertility drugs: results from a large Danish cohort study.

    PubMed

    Hannibal, Charlotte Gerd; Jensen, Allan; Sharif, Heidi; Kjaer, Susanne Krüger

    2008-09-01

    The aim was to examine the effects of fertility drugs on malignant melanoma risk using data from the largest cohort of infertile women to date. A cohort of 54,362 women with infertility problems referred to Danish fertility clinics in the period 1963-1998 was established. A detailed data collection including information about type and amount of treatment was conducted. Using case-cohort techniques, we calculated rate ratios (RRs) of malignant melanoma associated with different fertility drugs after adjustment for parity status. 112 malignant melanomas were identified during follow-up through 2000. Use of clomiphene, gonadotrophins, hCG or GnRH did not affect risk of malignant melanoma significantly. When stratifying for parity, however, use of gonadotrophins (RR = 2.29; CI: 1.16-4.52) or GnRH (RR = 3.26; 95% CI: 1.50-7.09) among parous women was associated with a significant increased risk. For all groups of fertility drugs, we found no association with number of cycles of use or years since first use (latency). Our findings showed no strong association between malignant melanoma risk and use of fertility drugs, although the results indicated that use of gonadotrophins or GnRH might increase risk in parous women. Longer follow-up is needed to confirm our findings.

  17. The application dosage of Azolla pinnata in fresh and powder form as organic fertilizer on soil chemical properties, growth and yield of rice plant

    NASA Astrophysics Data System (ADS)

    Setiawati, Mieke Rochimi; Damayani, Maya; Herdiyantoro, Diyan; Suryatmana, Pujawati; Anggraini, Derisfha; Khumairah, Fiqriah Hanum

    2018-02-01

    The yield of rice plants is strongly influenced by N fertilizer. Nitrogen in rice plants has roles in vegetative growth, tiller formation and increasing yield through rice protein formation. Nitrogen supplied from organic fertilizers is better than inorganic fertilizers that may have environmental problem effects. Organic fertilizers from Azolla pinnata water fern contain higher N than other organic fertilizers. Symbiosis between A. pinnata and the N-fixing cyanobacteria results in high content of nitrogen, 3 to 5%. A. pinnata can be added to the rice field as organic fertilizer in form of fresh biomass or composted. Composted form can be ground into powder which passes through 100 mesh sieve. Preparation of compost powder of A. pinnata is done to reduce the constraints of voluminous application of organic fertilizers and to improve the efficiency of its use. The objective of this research was to compare the effect of the use of fresh A. pinnata and compost powder of A. pinnata on some soil and plant chemical properties and rice yield. The treatments applied were fresh A. pinnata at the dose of 0, 10 and 20 ton ha-1 and A. pinnata compost powder at 12.5 and 25 kg ha-1. The results showed that incorporation of fresh A. pinnata at 20 tons ha-1 and its compost powder at 25 kg ha-1 increased the available P of soil, plant P content and tiller number, but did not affect the content of organic-C, total soil N, plant N content and rice yield. This study suggested the benefits of A. pinnata compost powder technology in organic fertilization of soil to increase the nutrient content of soil and rice plants.

  18. Levels and associations among self-esteem, fertility distress, coping, and reaction to potentially being a genetic carrier in women with diminished ovarian reserve

    PubMed Central

    Cizmeli, Ceylan; Lobel, Marci; Franasiak, Jason; Pastore, Lisa M.

    2013-01-01

    Objective To measure the level of distress and its relationship with other psychologic factors in women with diminished ovarian reserve (DOR) who participated in a fragile X genetics study. Design Longitudinal data analyzed with structural equation modeling. Setting Four U.S. private and academic fertility centers. Patient(s) Sixty-two infertile patients with DOR. Intervention(s) None. Main Outcome Measure(s) Fertility Problem Inventory, Coping Scale for Infertile Couples, Rosenberg Self-Esteem, Health Orientation Scale. Result(s) Nineteen percent had low fertility distress, 56% had average fertility distress, and 24% had high fertility distress. Thirty-six percent self-reported a “favorable” or “very favorable” emotional response to potentially being a fragile X carrier (termed “emotions”), 53% were “ambivalent,” and 11% had an unfavorable reaction. Three months after learning that they were not a carrier, these percentages were 91%, 9%, and 0%, respectively. Emotions at this second time point were significantly more positive than at pretesting. At baseline, higher self-esteem was a significant predictor of reduced fertility distress both directly and indirectly through emotions. Fertility distress was not associated with coping. Self-esteem, fertility distress, pretesting emotions, and coping were unrelated to posttesting emotions. Conclusion(s) The potential of having an explanation for one’s DOR condition may have a beneficial impact on women’s psychologic states during the process of genetic testing, and this appeared to be especially true for women with higher self-esteem. Psychologic interventions targeted to women with low self-esteem may reduce distress and improve reactions to genetic testing. PMID:23498890

  19. An Analysis of China's Fertilizer Policies: Impacts on the Industry, Food Security, and the Environment.

    PubMed

    Li, Yuxuan; Zhang, Weifeng; Ma, Lin; Huang, Gaoqiang; Oenema, Oene; Zhang, Fusuo; Dou, Zhengxia

    2013-07-01

    China has made remarkable strides in recent decades to grow enough food to feed 20% of the world's population with only 9% of the world's arable land. Meanwhile, the nation is experiencing exacerbated air and water pollution problems. Agricultural growth and the pollution aggravation are closely linked with policies affecting fertilizer production and use. Essentially nonexistent in 1950, China's fertilizer industry is now a robust conglomerate producing fertilizers in amounts that not only meet domestic demand but also contribute to international trade. The industry's growth stemmed from a series of policy progressions, featuring (i) a total control system with state ownership and central planning (1949-1984), (ii) a dual system of central planning and market adjustment (1985-1997), (iii) a market-driven system with government-mandated price caps (1998-2009), and (iv) a complete market-oriented system (since 2009). In conjunction with the policy changes were massive subsidy programs totaling more than $18 billion in 2010. The support policies and subsidies helped grow the industry and safeguard an adequate supply of fertilizers at affordable costs to farmers, but the artificially low-priced fertilizers also contributed to a nationwide trend of fertilizer overuse, leading to nutrient pollution. China needs innovative policies and programs to address food security and sustainability challenges. In this study, we review and analyze policies and programs related to China's fertilizer production and use in a 60-yr span (1950-2010) and discuss its impact on the development of the industry, food security, and pressing environmental issues. Finally, our study analyzes long-term trends in fertilizer use in China and offers some key viewpoints to stimulate debates among all stakeholders. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.

  20. The relative importance of fertilization and soil erosion on C-dynamics in agricultural landscapes of NE Germany

    NASA Astrophysics Data System (ADS)

    Pohl, Madlen; Hoffmann, Mathias; Hagemann, Ulrike; Jurisch, Nicole; Remus, Rainer; Sommer, Michael; Augustin, Jürgen

    2016-04-01

    The hummocky ground moraine landscape of north-east Germany is characterized by distinct small-scale soil heterogeneity on the one hand, and intensive energy crop cultivation on the other. Both factors are assumed to significantly influence gaseous C exchange, and thus driving the dynamics of soil organic carbon stocks in terrestrial, agricultural ecosystems. However, it is not yet clear to which extent fertilization and soil erosional status influence soil C dynamics and whether one of these factors is more relevant than the other. We present seasonal and dynamic soil C balances of biogas maize for the growing season 2011, recorded at different sites located within the CarboZALF experimental area. The sites differ regarding soils (non-eroded Albic Luvisols (Cutanic), extremely eroded Calcaric Regosol and depositional Endogleyic Colluvic Regosol,) and applied fertilizer (100% mineral N fertilizer, 50% mineral and 50% N organic fertilizer, 100% organic N fertilizer). Fertilization treatments were established on the Albic Luvisol (Cutanic). Net-CO2-exchange (NEE) and ecosystem respiration (Reco) were measured every four weeks using a dynamic flow-through non-steady-state closed manual chamber system. Gap filling was performed based on empirical temperature and PAR dependency functions to derive daily NEE values. At the same time, daily above-ground biomass production (NPP) was estimated based on biomass samples and final harvest, using a sigmoidal growth function. In a next step, dynamic soil C balances were generated as the balance of daily NEE and NPP considering the initial C input due to N fertilizers. The resulted seasonal soil C balances varied from strong C losses at the Endogleyic Colluvic Regosol (602 g C m-2) to C gains at the Calcaric Regosol (-132 g C m-2). In general, soils exerted a stronger impact on seasonal and dynamic C balances compared to differences in applied N fertilizer. There are indications that inter-annual variations in climate conditions and interactions between soil and fertilization types also seem to affect C-dynamics. Hence, long-term measurements of different fertilization treatments at characteristic soil landscape elements are needed.

  1. Temperature and rainfall are related to fertility rate after spring artificial insemination in small ruminants.

    PubMed

    Abecia, J A; Arrébola, F; Macías, A; Laviña, A; González-Casquet, O; Benítez, F; Palacios, C

    2016-10-01

    A total number of 1092 artificial inseminations (AIs) performed from March to May were documented over four consecutive years on 10 Payoya goat farms (36° N) and 19,392 AIs on 102 Rasa Aragonesa sheep farms (41° N) over 10 years. Mean, maximum, and minimum ambient temperatures, mean relative humidity, mean solar radiation, and total rainfall on each insemination day were recorded. Overall, fertility rates were 58 % in goats and 45 % in sheep. The fertility rates of the highest and lowest deciles of each of the meteorological variables indicated that temperature and rainfall had a significant effect on fertility in goats. Specifically, inseminations that were performed when mean (68 %), maximum (68 %), and minimum (66 %) temperatures were in the highest decile, and rainfall was in the lowest decile (59 %), had a significantly (P < 0.0001) higher proportion of does that became pregnant than did the ewes in the lowest decile (56, 54, 58, and 49 %, respectively). In sheep, the fertility rates of the highest decile of mean (62 %), maximum (62 %), and minimum (52 %) temperature, RH (52 %), THI (53 %), and rainfall (45 %) were significantly higher (P < 0.0001) than were the fertility rates among ewes in the lowest decile (46, 45, 45, 45, 46, and 43 %, respectively). In conclusion, weather was related to fertility in small ruminants after AI in spring. It remains to be determined whether scheduling the dates of insemination based on forecasted temperatures can improve the success of AI in goats and sheep.

  2. Method for reducing CO2, CO, NOX, and SOx emissions

    DOEpatents

    Lee, James Weifu; Li, Rongfu

    2002-01-01

    Industrial combustion facilities are integrated with greenhouse gas-solidifying fertilizer production reactions so that CO.sub.2, CO, NO.sub.x, and SO.sub.x emissions can be converted prior to emission into carbonate-containing fertilizers, mainly NH.sub.4 HCO.sub.3 and/or (NH.sub.2).sub.2 CO, plus a small fraction of NH.sub.4 NO.sub.3 and (NH.sub.4).sub.2 SO.sub.4. The invention enhances sequestration of CO.sub.2 into soil and the earth subsurface, reduces N0.sub.3.sup.- contamination of surface and groundwater, and stimulates photosynthetic fixation of CO.sub.2 from the atmosphere. The method for converting CO.sub.2, CO, NO.sub.x, and SO.sub.x emissions into fertilizers includes the step of collecting these materials from the emissions of industrial combustion facilities such as fossil fuel-powered energy sources and transporting the emissions to a reactor. In the reactor, the CO.sub.2, CO, N.sub.2, SO.sub.x, and/or NO.sub.x are converted into carbonate-containing fertilizers using H.sub.2, CH.sub.4, or NH.sub.3. The carbonate-containing fertilizers are then applied to soil and green plants to (1) sequester inorganic carbon into soil and subsoil earth layers by enhanced carbonation of groundwater and the earth minerals, (2) reduce the environmental problem of NO.sub.3.sup.- runoff by substituting for ammonium nitrate fertilizer, and (3) stimulate photosynthetic fixation of CO.sub.2 from the atmosphere by the fertilization effect of the carbonate-containing fertilizers.

  3. Essay Review: College Sports since World War II

    ERIC Educational Resources Information Center

    Thelin, John

    2011-01-01

    Scholarly writing on college sports gets better as the problems of college sports get worse. This does not mean that the authors are causing the problems. Rather, the excesses and ills of college sports, past and present, provide such fertile data that historians of higher education enjoy a perverse embarrassment of research riches. This maxim is…

  4. Women in Toxic Work Environments: A Case Study of Social Problem Development.

    ERIC Educational Resources Information Center

    Randall, Donna M.; Short, James F., Jr.

    1983-01-01

    Uses the Spector and Kitsuse model of social problem development to analyze the controversy over the refusal of the Bunker Hill Company (Kellogg, Idaho) to give fertile female employees jobs involving exposure to lead unless they were sterilized. Suggests modifications in the model to account for the government role in claims making. (Author/MJL)

  5. Connecting Authentic Activities with Multimedia to Enhance Teaching and Learning, an Exemplar from Scottish History

    ERIC Educational Resources Information Center

    Hillis, Peter

    2010-01-01

    Much of the current focus on maximizing the potential of ICT to enhance teaching and learning is on learning tasks rather than the technology. These learning tasks increasingly employ a constructivist, problem-based methodology especially one based around authentic learning. The problem-based nature of history provides fertile ground for this…

  6. Mexican Rhetoric: Exigency and Background--A Sketch.

    ERIC Educational Resources Information Center

    Blythin, Evan

    Presuming that rhetorical discourse comes into existence as a response to a situation in the same sense that an answer comes into existence in response to a question, or a solution in response to a problem, then Mexico is fertile ground for rhetoric and the study of rhetoric. Mexico is a country under fire. Economic and political problems threaten…

  7. An Address on the Population Problem: Address to the Massachusetts Institute of Technology.

    ERIC Educational Resources Information Center

    McNamara, Robert S.

    In this speech, Robert McNamara examines the background of the world population problem, analyzes its current trends, evaluates the measures available to deal with it, and suggests actions governments and others can take to help solve it. It now appears that significant fertility decline may have begun in developing countries. Data seem to…

  8. Vanishing White Matter Disease

    MedlinePlus

    ... which can result in lack of menstrual periods, fertility problems and early menopause. Mental decline may be ... production, especially the decrease in protein synthesis during stress conditions, such as fever and infection. It is ...

  9. Long-term changes in the chemical composition of soil organic matter, depending on fertilization and crop rotation

    NASA Astrophysics Data System (ADS)

    Tammik, Kerttu; Kauer, Karin; Astover, Alar

    2017-04-01

    The objective of this study was to determine whether it is possible to assess the impact of different management practices (crop rotation, fertilization (organic and mineral fertilizers) on the chemical composition of soil organic matter, using Fourier transform infrared spectroscopy (FTIR). The study is based IOSDV long-term (established in 1989) three field crop rotation (potato-wheat-barely) experiment located in Tartu, Estonia. Soil samples (Stagnic Albeluvisol) were collected from the 0-20 cm depth in the autumn of 2015, air dried, sieved to 2 mm and grinded to obtain homogeneous samples. The content of soil organic matter was measured by the dry combustion method in a varioMax CNS elemental analyser (ELEMENTAR, Germany). The samples were analysed using Thermo-Nicolet iS10 Fourier Transform Infrared Spectrophotometer (FT-IR) and OMNIC software. An intense and sharp peak was recorded in the region of Si-O vibrations of clay minerals and polysaccharides in all samples analysed. The volume of the peak correlated with the quantity of fertilizers administered

  10. Treating Woman with Myo-Inositol Vaginal Suppositories Improves Partner's Sperm Motility and Fertility.

    PubMed

    Montanino Oliva, Mario; Poverini, Roberta; Lisi, Rosella; Carra, Maria Cristina; Lisi, Franco

    2016-01-01

    Motility is the feature that allows spermatozoa to actively reach and penetrate the female gamete during fertilization. When this function is altered, and especially decreased, troubles in conceiving may occur. In this study, we demonstrated that treating fertile women with myo-inositol (MI) vaginal suppositories ameliorated their partners' sperm motility and also positively affected their conceiving capacity, without changes in cervical mucus structural and biochemical characteristics. Indeed, by means of the postcoital test on female cervical mucus, a significant improvement especially in progressive sperm motility was recorded after MI suppository use. Concomitantly, after MI treatment, a reduction of immotile spermatozoa percentage was observed. Importantly, MI vaginal supplementation positively correlated with a pregnancy for 5 of the 50 couples enrolled in the study, leading us to speculate that this substance may substantially contribute to create in the cervical mucus an ideal milieu that makes spermatozoa more motile and functionally able to fertilize. Even though the detailed mechanism is still unclear, these results should encourage MI vaginal use for the clinical improvement of male infertility, through their partners.

  11. Treating Woman with Myo-Inositol Vaginal Suppositories Improves Partner's Sperm Motility and Fertility

    PubMed Central

    Poverini, Roberta; Lisi, Rosella; Carra, Maria Cristina; Lisi, Franco

    2016-01-01

    Motility is the feature that allows spermatozoa to actively reach and penetrate the female gamete during fertilization. When this function is altered, and especially decreased, troubles in conceiving may occur. In this study, we demonstrated that treating fertile women with myo-inositol (MI) vaginal suppositories ameliorated their partners' sperm motility and also positively affected their conceiving capacity, without changes in cervical mucus structural and biochemical characteristics. Indeed, by means of the postcoital test on female cervical mucus, a significant improvement especially in progressive sperm motility was recorded after MI suppository use. Concomitantly, after MI treatment, a reduction of immotile spermatozoa percentage was observed. Importantly, MI vaginal supplementation positively correlated with a pregnancy for 5 of the 50 couples enrolled in the study, leading us to speculate that this substance may substantially contribute to create in the cervical mucus an ideal milieu that makes spermatozoa more motile and functionally able to fertilize. Even though the detailed mechanism is still unclear, these results should encourage MI vaginal use for the clinical improvement of male infertility, through their partners. PMID:27403162

  12. Ethical issues involved with in vitro fertilization.

    PubMed

    Shannon, T A

    1990-09-01

    There are three elements to consider with in vitro fertilization. First, the paramount concern needs to be the well-being and best interests of the child, even though he or she may be an embryo at the time. Second, some people think a child will solve their marital problems. Although couples seeking in vitro fertilization should not be subjected to more scrutiny than couples conceiving in the traditional way, the stresses and uncertainties of in vitro fertilization can further strain a marriage. Clinic staff members should be sensitive to this issue as a way of helping to avoid complications later. Third, how we resolve the status and fate of the frozen embryo and who has disposition over it surely will reflect how we consider abortion rights. For example, if the standards of Roe vs Wade were applied, one could argue that the woman should have total disposition over the frozen embryo. On the other hand, if the father receives a say in the matter, what impact would this have? Given the nature of our society and the tenuous state of marriage, the problem of disposing frozen embryos is a critical one that has no satisfactory solution. Finally, there is the stress factor. Although this is not an issue of direct ethical concern, it is related to the necessity of the couple receiving accurate information. If the couple receives an incorrect impression of a clinic's success rates, they may be exposed unnecessarily to further stress and frustration.(ABSTRACT TRUNCATED AT 250 WORDS)

  13. Assessment of expected breeding values for fertility traits of Murrah buffaloes under subtropical climate.

    PubMed

    Dash, Soumya; Chakravarty, A K; Singh, Avtar; Shivahre, Pushp Raj; Upadhyay, Arpan; Sah, Vaishali; Singh, K Mahesh

    2015-03-01

    The aim of the present study was to assess the influence of temperature and humidity prevalent under subtropical climate on the breeding values for fertility traits viz. service period (SP), pregnancy rate (PR) and conception rate (CR) of Murrah buffaloes in National Dairy Research Institute (NDRI) herd. Fertility data on 1379 records of 581 Murrah buffaloes spread over four lactations and climatic parameters viz. dry bulb temperature and relative humidity (RH) spanned over 20 years (1993-2012) were collected from NDRI and Central Soil and Salinity Research Institute, Karnal, India. Monthly average temperature humidity index (THI) values were estimated. Threshold THI value affecting fertility traits was identified by fixed least-squares model analysis. Three zones of non-heat stress, heat stress and critical heat stress zones were developed in a year. The genetic parameters heritability (h(2)) and repeatability (r) of each fertility trait were estimated. Genetic evaluation of Murrah buffaloes was performed in each zone with respect to their expected breeding values (EBV) for fertility traits. Effect of THI was found significant (p<0.001) on all fertility traits with threshold THI value identified as 75. Based on THI values, a year was classified into three zones: Non heat stress zone(THI 56.71-73.21), HSZ (THI 75.39-81.60) and critical HSZ (THI 80.27-81.60). The EBVfor SP, PR, CR were estimated as 138.57 days, 0.362 and 69.02% in non-HSZ while in HSZ EBV were found as 139.62 days, 0.358 and 68.81%, respectively. EBV for SP was increased to 140.92 days and for PR and CR, it was declined to 0.357 and 68.71% in critical HSZ. The negative effect of THI was observed on EBV of fertility traits under the non-HSZ and critical HSZ Thus, the influence of THI should be adjusted before estimating the breeding values for fertility traits in Murrah buffaloes.

  14. Who should be offered sperm banking for fertility preservation? A survey of UK oncologists and haematologists.

    PubMed

    Gilbert, E; Adams, A; Mehanna, H; Harrison, B; Hartshorne, G M

    2011-05-01

    Fertility after cancer therapy is a significant quality-of-life concern for many patients, their partners and families. Authoritative guidance states that men whose fertility may be affected by impending therapies should be offered sperm banking. Yet some patients are not offered this opportunity and are thereby disadvantaged. We sought to understand oncologists' and haematologists' decision making concerning sperm-banking referrals. We surveyed all oncologists and haematologists on the Royal College of Radiotherapists' Faculty of Oncology and British Society for Haematology circulation lists. From 2357 across all specialties, 499 responses were received: 253 haematologists and 246 oncologists (21% response rate). Twenty-one percent of respondents were unaware of local policies on sperm banking and 42% considered that sperm banking should be offered to more patients. Respondents' decisions reveal either assumptions about patients' needs based on characteristics such as age, sexual orientation and severity of illness or the influence of their own moral conclusions upon their patients. The survey identified paucity of training for clinicians, information for patients and systematic recording of discussions about fertility. A robust care infrastructure supporting male fertility storage is needed urgently to include targeted information for cancer clinicians and patients, identified individuals responsible for coordination and documentation of discussions with patients.

  15. A prospective randomized study comparing two commercially available types of human embryo culture media: G1-PLUS™/G2-PLUS™ sequential medium (Vitrolife) and the GL BLAST™ sole medium (Ingamed).

    PubMed

    Ceschin, Ianae I; Ribas, Mariana H; Ceschin, Alvaro P; Nishikawa, Lucileine; Rocha, Claudia C; Pic-Taylor, Aline; Baroneza, José Eduardo

    2016-03-01

    To check the efficacy of two types of commercially available embryo culture medium: G1-PLUS™/G2-PLUS™ sequential (Vitrolife, Gothenburg, Sweden) and GV BLAST™ sole (Ingamed, Maringá, Brazil) with regards to fertilization, cleavage, blastocyst and pregnancy rates. Prospective and randomized study conducted from March to July 2015, using the medical records of 60 patients submitted to Intracytoplasmic Sperm Injection techniques (ICSI). Data regarding the age of patients, together with fertilization, cleavage, blastocyst and pregnancy rates, were collected and compared in relation to the: G1-PLUS™/G2-PLUS™ sequential and GV BLAST™ sole mediums. The data were tabulated and compared using the Pearson's Chi-Square test (95% CI). There was no significant difference when comparing patients divided into higher and lower fertility age. No significant statistical difference was noted between the fertilization rates (P=0.59), cleavage (P=0.91), evolution to blastocyst (P=0.33) and total pregnancy (P=0.83) when comparing the embryos cultured in the different media analysed. We conclude that the G1-PLUS™/G2-PLUS™ sequential and GV BLAST™ sole mediums are equally effective with regards to fertilization, cleavage, blastocyst development and total pregnancy rates.

  16. Near-Infrared Spectroscopy and Imaging Studies of Fertilized Fish Eggs: In Vivo Monitoring of Egg Growth at the Molecular Level

    NASA Astrophysics Data System (ADS)

    Ishigaki, Mika; Kawasaki, Shoya; Ishikawa, Daitaro; Ozaki, Yukihiro

    2016-01-01

    In this work, the growth of fertilized Japanese medaka (Oryzias latipes) eggs was monitored in vivo at the molecular level using near-infrared (NIR) spectroscopy and NIR imaging. NIR spectra were recorded noninvasively for three major parts of a fertilized medaka egg, the embryonic body, the oil droplets, and the yolk, from the first day after fertilization to the day before hatching. Principal component analysis (PCA) revealed that water, protein, and lipid contents in the egg yolk and oil droplets changed significantly just before hatching. The ratio of the characteristic peaks due to proteins and lipids in the second derivative spectra suggested that the relative concentration of proteins to lipids was constant in the egg yolk, while it dramatically increased just before hatching in the oil droplets. Furthermore, linear discriminant analysis (LDA) predicted the hatching possibility on the next day with 100% and 99.3% accuracy for yolk and oil droplets data, respectively. Two types of NIR images were developed in situ using the band intensities of the lipids and proteins in the second derivative spectra. The egg’s protein and lipid content was successfully visualized noninvasively. This technique should enable noninvasive quality testing of fertilized eggs in the future.

  17. Effect of dry mycelium of Penicillium chrysogenum fertilizer on soil microbial community composition, enzyme activities and snap bean growth.

    PubMed

    Wang, Bing; Liu, Huiling; Cai, Chen; Thabit, Mohamed; Wang, Pu; Li, Guomin; Duan, Ziheng

    2016-10-01

    The dry mycelium fertilizer (DMF) was produced from penicillin fermentation fungi mycelium (PFFM) following an acid-heating pretreatment to degrade the residual penicillin. In this study, it was applied into soil as fertilizer to investigate its effects on soil properties, phytotoxicity, microbial community composition, enzyme activities, and growth of snap bean in greenhouse. As the results show, pH, total nitrogen, total phosphorus, total potassium, and organic matter of soil with DMF treatments were generally higher than CON treatment. In addition, the applied DMF did not cause heavy metal and residual drug pollution of the modified soil. The lowest GI values (<0.3) were recorded at DMF8 (36 kg DMF/plat) on the first days after applying the fertilizer, indicating that severe phytotoxicity appeared in the DMF8-modified soil. Results of microbial population and enzyme activities illustrated that DMF was rapidly decomposed and the decomposition process significantly affected microbial growth and enzyme activities. The DMF-modified soil phytotoxicity decreased at the late fertilization time. DMF1 was considered as the optimum amount of DMF dose based on principal component analysis scores. Plant height and plant yield of snap bean were remarkably enhanced with the optimum DMF dose.

  18. Menstrual Cycle Phase Does Not Predict Political Conservatism

    PubMed Central

    Scott, Isabel M.; Pound, Nicholas

    2015-01-01

    Recent authors have reported a relationship between women's fertility status, as indexed by menstrual cycle phase, and conservatism in moral, social and political values. We conducted a survey to test for the existence of a relationship between menstrual cycle day and conservatism. 2213 women reporting regular menstrual cycles provided data about their political views. Of these women, 2208 provided information about their cycle date, 1260 provided additional evidence of reliability in self-reported cycle date, and of these, 750 also indicated an absence of hormonal disruptors such as recent hormonal contraception use, breastfeeding or pregnancy. Cycle day was used to estimate day-specific fertility rate (probability of conception); political conservatism was measured via direct self-report and via responses to the "Moral Foundations” questionnaire. We also recorded relationship status, which has been reported to interact with menstrual cycle phase in determining political preferences. We found no evidence of a relationship between estimated cyclical fertility changes and conservatism, and no evidence of an interaction between relationship status and cyclical fertility in determining political attitudes. Our findings were robust to multiple inclusion/exclusion criteria and to different methods of estimating fertility and measuring conservatism. In summary, the relationship between cycle-linked reproductive parameters and conservatism may be weaker or less reliable than previously thought. PMID:25923332

  19. Menstrual cycle phase does not predict political conservatism.

    PubMed

    Scott, Isabel M; Pound, Nicholas

    2015-01-01

    Recent authors have reported a relationship between women's fertility status, as indexed by menstrual cycle phase, and conservatism in moral, social and political values. We conducted a survey to test for the existence of a relationship between menstrual cycle day and conservatism. 2213 women reporting regular menstrual cycles provided data about their political views. Of these women, 2208 provided information about their cycle date, 1260 provided additional evidence of reliability in self-reported cycle date, and of these, 750 also indicated an absence of hormonal disruptors such as recent hormonal contraception use, breastfeeding or pregnancy. Cycle day was used to estimate day-specific fertility rate (probability of conception); political conservatism was measured via direct self-report and via responses to the "Moral Foundations" questionnaire. We also recorded relationship status, which has been reported to interact with menstrual cycle phase in determining political preferences. We found no evidence of a relationship between estimated cyclical fertility changes and conservatism, and no evidence of an interaction between relationship status and cyclical fertility in determining political attitudes. Our findings were robust to multiple inclusion/exclusion criteria and to different methods of estimating fertility and measuring conservatism. In summary, the relationship between cycle-linked reproductive parameters and conservatism may be weaker or less reliable than previously thought.

  20. Development and Evaluation of a Low Fertility Ontology for Analyzing Social Data in Korea.

    PubMed

    Lee, Ji-Hyun; Park, Hyeoun-Ae; Song, Tae-Min

    2016-01-01

    The purpose of this study is to develop a low fertility ontology for collecting and analyzing social data. A low fertility ontology was developed according to Ontology Development 101 and formally represented using Protégé. The content coverage of the ontology was evaluated using 1,387 narratives posted by the public and 63 narratives posted by public servants. Six super-classes of the ontology were developed based on Bronfenbrenner's ecological system theory with an individual in the center and environmental systems impacting their as surroundings. In total, 568 unique concepts were extracted from the narratives. Out of these concepts, 424(74.6%) concepts were lexically or semantically mapped, 67(11.8%) were either broadly or narrowly mapped to the ontology concepts. Remaining 77(13.6%) concepts were not mapped to any of the ontology concepts. This ontology can be used as a framework to understand low fertility problems using social data in Korea.

  1. What women want from women's reproductive health research: a qualitative study.

    PubMed

    Pandey, Shilpi; Porter, Maureen; Bhattacharya, Siladitya

    2015-12-01

    Researchers are being urged to involve patients in the design and conduct of studies in health care with limited insight at present into their needs, abilities or interests. This is particularly true in the field of reproductive health care where many conditions such as pregnancy, menopause and fertility problems involve women who are otherwise healthy. To ascertain the feasibility of involving patients and members of the public in research on women's reproductive health care (WRH). University and tertiary care hospital in north-east Scotland; 37 women aged 18-57. Four focus groups and one individual interview were audio-recorded and verbatim transcripts analysed thematically by two researchers using a grounded theory approach. Most participants were interested in WRH, but some participated to promote a health issue of special concern to them. Priorities for research reflected women's personal concerns: endometriosis, polycystic ovary syndrome, menopause, fertility risks of delaying parenthood and early post-natal discharge from hospital. Women were initially enthusiastic about getting involved in research on WRH at the design or delivery stage, but after discussion in focus groups, some questioned their ability to do so or the time available to commit to research. None of the respondents expected payment for any involvement, believing that the experience would be rewarding enough in itself. Involving patients and public in research would include different perspectives and priorities; however, recruiting for this purpose would be challenging. © 2014 John Wiley & Sons Ltd.

  2. [Effect of mixed edaphic bacterial inoculants in the early development of improved cocoa cultivars (Theobroma cacao L.) in a traditional agroforestry system of Oaxaca, Mexico].

    PubMed

    Hipólito-Romero, E; Carcaño-Montiel, M G; Ramos-Prado, J M; Vázquez-Cabañas, E A; López-Reyes, L; Ricaño-Rodríguez, J

    Cocoa plant (Theobroma cacao L.) is native from South America and it represents one of the most significant "bio-cultural" resources of Mesoamerica, since it is a region where it was domesticated and had a relevance as ritual drink and as currency in many pre-hispanic cultures until the arrival of the Spaniards who spread its use worldwide, and became it one of the most consumed commodity goods. Through this research, an alternative is proposed to address the problem of cultivars through the introduction of a wide variety of cocoa plants in traditional agroforestry systems, in synergy with the inoculation of nitrogen-fixing and insoluble phosphor solubilizing edaphic bacterial consortia. Four cultivars of improved grafted cocoa plants were introduced in a traditional agroforestry plot and three fertilization treatments were applied: application of biofertilizer, application of chemical fertilizer and control. Measurements of height, stem diameter, number of leaves and branches were recorded at 2 and 12 months after planting and rhizosphere microbial populations were characterized. Growth results showed good potential for all studied cultivars and it was observed that biofertilization foresees significant effects in some of the growth indicators of cocoa plant. Thereby, plant associations in an agroforestry system could be favorable to promote fruit development and resistance to pests and diseases. Copyright © 2017 Asociación Argentina de Microbiología. Publicado por Elsevier España, S.L.U. All rights reserved.

  3. [Effects of CO2 fertilization on photosynthesis and growth of cut Anthurium andraeanum in solar greenhouse in winter].

    PubMed

    Yang, Ke Bin; Meng, Fan Zhi; Guo, Xian Feng

    2017-06-18

    Aiming at the problem of the acute shortage of CO 2 in winter production of cut Anthurium andraeanum in solar greenhouse, the effect of CO 2 fertilization on photosynthetic characteristics and growth performance of A. andraeanum 'Fire' was investigated. Three treatments with different concentrations of CO 2 were designed, i.e., 700, 1000 and 1300 Μmol·mol -1 , with receiving no extra CO 2 as the control. The results showed that for the CO 2 -fertilized plants, the photosynthetic rate, intercellular CO 2 concentration and water use efficiency were significantly greater than those in the control plants after CO 2 fertilization for 60 days, and the largest increase range was observed in the 1000 Μmol·mol -1 CO 2 treatment, whereas the stomata conductance was significantly reduced compared with the control. Meanwhile, the contents of soluble sugar, starch and soluble protein in CO 2 -fertilized plants were significantly higher than those in control plants. Moreover, the quality of cut flowers with CO 2 fertilization was remarkably superior to control flowers in term of the parameters including spathe size, spathe color, peduncle length, leaf growth performance and peduncle growth rate. The most superior improvement was observed in the 1000 Μmol·mol -1 CO 2 treatment. It was therefore concluded that CO 2 fertilization of 1000 Μmol·mol -1 could effectively improve the winter production of cut A. andraeanum in solar greenhouse.

  4. The effect of celery (Apium graveolens L.) on fertility: A systematic review.

    PubMed

    Kooti, Wesam; Moradi, Maryam; Peyro, Khadijeh; Sharghi, Maedeh; Alamiri, Fatima; Azami, Milad; Firoozbakht, Mohammad; Ghafourian, Mehri

    2017-10-06

    Background Fertility and infertility problems are among the complex issues in medicine. The use of herbal products in the treatment of fertility has been considered as an alternative to synthetic drugs. Celery containing known compounds can have an impact on the fertility rate. The aim of this study was to do a systematic review on conducted studies in conjunction with the celery and reproduction. Methods Required papers were searched from databases like Science direct, PubMed, Scopus, and Springer. Keywords used in this study were "Apium graveolens L.", "fertility", "reproductive system", "sperm", "testis", "delivery", "sexual hormone", "LH", "FSH", "testosterone", "semen", "male", and "female". Out of 238 collected articles (published in the period 1995 to 2015), 222 were excluded due to non-relevance and lack of access to the original article. Results The notable points were the different results seen by different researchers during different treatment periods or at different doses. Of the 16 studies reviewed in this study, 13 studies have mentioned the positive effect of celery on fertility, while three studies reported the inhibitory effects of this plant. Conclusions Celery can have protective effects against substances such as sodium valproate, propylene glycol, and diethyl phthalate causing damages to the testicular structure and spermatogenesis. In this regard, the doses used and the treatment time while using the plant must be accurately investigated. Since there are compounds such as apigenin, the celery can induce inhibitory effects on fertility in case of chronic use or high concentration.

  5. Single gene and gene interaction effects on fertilization and embryonic survival rates in cattle.

    PubMed

    Khatib, H; Huang, W; Wang, X; Tran, A H; Bindrim, A B; Schutzkus, V; Monson, R L; Yandell, B S

    2009-05-01

    Decrease in fertility and conception rates is a major cause of economic loss and cow culling in dairy herds. Conception rate is the product of fertilization rate and embryonic survival rate. Identification of genetic factors that cause the death of embryos is the first step in eliminating this problem from the population and thereby increasing reproductive efficiency. A candidate pathway approach was used to identify candidate genes affecting fertilization and embryo survival rates using an in vitro fertilization experimental system. A total of 7,413 in vitro fertilizations were performed using oocytes from 504 ovaries and semen samples from 10 different bulls. Fertilization rate was calculated as the number of cleaved embryos 48 h postfertilization out of the total number of oocytes exposed to sperm. Survival rate of embryos was calculated as the number of blastocysts on d 7 of development out of the number of total embryos cultured. All ovaries were genotyped for 8 genes in the POU1F1 signaling pathway. Single-gene analysis revealed significant associations of GHR, PRLR, STAT5A, and UTMP with survival rate and of POU1F1, GHR, STAT5A, and OPN with fertilization rate. To further characterize the contribution of the entire integrated POU1F1 pathway to fertilization and early embryonic survival, a model selection procedure was applied. Comparisons among the different models showed that interactions between adjacent genes in the pathway revealed a significant contribution to the variation in fertility traits compared with other models that analyzed only bull information or only genes without interactions. Moreover, some genes that were not significant in the single-gene analysis showed significant effects in the interaction analysis. Thus, we propose that single genes as well as an entire pathway can be used in selection programs to improve reproduction performance in dairy cattle.

  6. The cultural evolution of fertility decline

    PubMed Central

    Colleran, Heidi

    2016-01-01

    Cultural evolutionists have long been interested in the problem of why fertility declines as populations develop. By outlining plausible mechanistic links between individual decision-making, information flow in populations and competition between groups, models of cultural evolution offer a novel and powerful approach for integrating multiple levels of explanation of fertility transitions. However, only a modest number of models have been published. Their assumptions often differ from those in other evolutionary approaches to social behaviour, but their empirical predictions are often similar. Here I offer the first overview of cultural evolutionary research on demographic transition, critically compare it with approaches taken by other evolutionary researchers, identify gaps and overlaps, and highlight parallel debates in demography. I suggest that researchers divide their labour between three distinct phases of fertility decline—the origin, spread and maintenance of low fertility—each of which may be driven by different causal processes, at different scales, requiring different theoretical and empirical tools. A comparative, multi-level and mechanistic framework is essential for elucidating both the evolved aspects of our psychology that govern reproductive decision-making, and the social, ecological and cultural contingencies that precipitate and sustain fertility decline. PMID:27022079

  7. Waste rock revegetation: Evaluation of nutrient and biological amendments

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meikle, T.W.; Lu, S.; Barta, J.P.

    1999-07-01

    Lack of salvaged topsoil for the reclamation of historical waste rock piles is a common problem in the arid Great Basin region. Utilization of amended waste rock as a growth media could reduce further disturbance resulting from topsoil harvest, minimize hauling costs, and potentially allow for the use of a higher quality material for plant growth. Getchell Gold Corporation initiated a study in 1995 to determine the suitability of waste rock substrates to support plant growth following application of nutrient and biological amendments. Three nutrient amendments and a biological seed treatment were evaluation for use in establishing vegetative cover onmore » three distinct waste rock substrates. Completely randomized blocks were placed on the three substrates. Treatments included organic fertilizers (Biosol and Gro-Power), a mineral fertilizer (16-20-0), and Azospirillum bacterial inoculant, plus controls. The seed mix consisted of Agropyron riparium, Agropyron spicatum, Elymus cinereus, Poa secunda, and Sitanion hystrix. Canopy and ground cover were monitored for three growing seasons. Conclusions from the study are: (1) two of the three substrates supported plant growth following amendment with organic fertilizers; (2) organic fertilizers increased cover substantially over the mineral fertilizer; and (3) Azospirillum had no effect on canopy cover.« less

  8. Hypogonadism and fertility issues following primary treatment for testicular cancer.

    PubMed

    Oldenburg, Jan

    2015-09-01

    The majority of testicular cancer (TC) patients are cured and expected to live for decades after treatment, such that knowledge about hypogonadism and fertility issues is particularly important for the group of testicular cancer survivors (TCSs). Hypogonadism and fertility issues are related to treatment intensity. In order to give an overview about hypogonadism in testicular cancer survivors (TCSs) the literature was reviewed. Testicular dysfunction was defined as inadequate spermatogenesis, as reflected by increased levels of Follicle Stimulating Hormone (FSH) and reduced fertility and/with or without insufficient testosterone (T) production with or without compensatory increased Luteinizing Hormone (LH) levels. Hypogonadism may lead to reduced sexual functioning and well-being, fertility problems, muscle weakness, loss of energy, and depression. Furthermore, hypogonadism also increases the risk of osteoporosis and is associated with the metabolic syndrome and cardiovascular disease (CVD). The hypothesized "Testicular Dysgenesis Syndrome" comprising low sperm counts, hypospadias, cryptorchidism, and finally TC, probably contributes to hypogonadism independent of applied TC treatment. Recently, an increased risk of accelerated hormonal ageing has been reported in TCSs in the very long term, i.e. 20 years after TC treatment. Copyright © 2015 Elsevier Inc. All rights reserved.

  9. Evaluation of body condition score measured throughout lactation as an indicator of fertility in dairy cattle.

    PubMed

    Banos, G; Brotherstone, S; Coffey, M P

    2004-08-01

    Body condition score (BCS) records of primiparous Holstein cows were analyzed both as a single measure per animal and as repeated measures per sire of cow. The former resulted in a single, average, genetic evaluation for each sire, and the latter resulted in separate genetic evaluations per day of lactation. Repeated measure analysis yielded genetic correlations of less than unity between days of lactation, suggesting that BCS may not be the same trait across lactation. Differences between daily genetic evaluations on d 10 or 30 and subsequent daily evaluations were used to assess BCS change at different stages of lactation. Genetic evaluations for BCS level or change were used to estimate genetic correlations between BCS measures and fertility traits in order to assess the capacity of BCS to predict fertility. Genetic correlation estimates with calving interval and non-return rate were consistently higher for daily BCS than single measure BCS evaluations, but results were not always statistically different. Genetic correlations between BCS change and fertility traits were not significantly different from zero. The product of the accuracy of BCS evaluations with their genetic correlation with the UK fertility index, comprising calving interval and non-return rate, was consistently higher for daily than for single BCS evaluations, by 28 to 53%. This product is associated with the conceptual correlated response in fertility from BCS selection and was highest for early (d 10 to 75) evaluations.

  10. Effect of caffeine on motility and vitality of sperm and in vitro fertilization of outbreed mouse in T6 and M16 media.

    PubMed

    Nabavi, Narges; Todehdehghan, Fatemeh; Shiravi, Abdollhossein

    2013-09-01

    Caffeine increases the CAMP production that stimulates spermatozoa movement. Caffeine is also used for induction of in vitro acrosome reaction in mammalian spermatozoa, an important step in achieving fertilization. The aim of this study was to assess the effect of caffeine on sperm's motility, vitality and laboratory fertilization rates in mouse in two T6 and M16 media. Epididymal mouse sperms were collected and treated by caffine in T6 and M16 media and their motility and vitality rates were evaluated. The pretreated sperms were added to oocytes in T6 and M16 media with and without caffeine and fertilization rates were recorded after 24 hours incubation. Sperm's motility (81.7±1.67%) and vitality (88.7±1.33%) rates and percentage of fertilized oocytes (67.52±8.16%) in T6 medium plus caffeine compare to control group have increased and shown significant differences at p≤0.01. While the percentages of these parameters in M16 medium supplemented with caffeine were 68.3±6.01%, 78±6.11%, and 42.6±12.96 respectively and in comparison to control group (M16 without caffeine) have not shown significant differences. Addition of caffeine to T6 medium promotes the sperm's motility and vitality and enhances fertilization and early in vitro development of mouse embryos. This article extracted from M.Sc. thesis. (Narges Navabi).

  11. Impact of ketorolac administration around ovarian stimulation on in vivo and in vitro fertilization and subsequent embryo development.

    PubMed

    Jee, Byung Chul; Youm, Hye Won; Lee, Jae Ho; Kim, Jee Hyun; Suh, Chang Suk; Kim, Seok Hyun

    2013-05-01

    We performed this study to investigate the effect of ketorolac (a non-steroidal anti-inflammatory drug) administration around ovarian stimulation on in vivo and in vitro fertilization process. Sixty-four female mice (ICR) were injected with ketorolac (0, 7.5, 15 and 30 µg/d) for 3 d starting from the day of eCG treatment. In experiment 1, 41 mice were triggered by hCG and then mated; two-cell embryos were obtained and in vitro development up to blastocyst was observed. In experiment 2, 23 mice were triggered by hCG and mature oocytes were collected; in vitro fertilization rate and subsequent embryo development up to blastocyst was recorded. In experiment 1, the blastocyst-forming rates per in vivo fertilized two-cell embryo showed an inverse relationship with a dosage of ketorolac (97.6%, 64.2%, 35.4% and 25.9%). In experiment 2, degenerated oocytes were frequently observed in a dose-dependent manner (4.3%, 22.9%, 22.4% and 75.0%). Lower fertilization rates were noted in all the three ketorolac-treating groups; blastocyst-forming rate was significantly lower in 30-µg-treating group when compared with the control group. Administration of ketorolac around ovarian stimulation significantly affects the development of in vivo fertilized embryo in a dose-dependent manner. High-dose ketorolac could result in a poor oocyte quality and decreased embryo developmental competence.

  12. Improving the reliability of female fertility breeding values using type and milk yield traits that predict energy status in Australian Holstein cattle.

    PubMed

    González-Recio, O; Haile-Mariam, M; Pryce, J E

    2016-01-01

    The objectives of this study were (1) to propose changing the selection criteria trait for evaluating fertility in Australia from calving interval to conception rate at d 42 after the beginning of the mating season and (2) to use type traits as early fertility predictors, to increase the reliability of estimated breeding values for fertility. The breeding goal in Australia is conception within 6 wk of the start of the mating season. Currently, the Australian model to predict fertility breeding values (expressed as a linear transformation of calving interval) is a multitrait model that includes calving interval (CVI), lactation length (LL), calving to first service (CFS), first nonreturn rate (FNRR), and conception rate. However, CVI has a lower genetic correlation with the breeding goal (conception within 6 wk of the start of the mating season) than conception rate. Milk yield, type, and fertility data from 164,318 cow sired by 4,766 bulls were used. Principal component analysis and genetic correlation estimates between type and fertility traits were used to select type traits that could subsequently be used in a multitrait analysis. Angularity, foot angle, and pin set were chosen as type traits to include in an index with the traits that are included in the multitrait fertility model: CVI, LL, CFS, FNRR, and conception rate at d 42 (CR42). An index with these 8 traits is expected to achieve an average bull first proof reliability of 0.60 on the breeding objective (conception within 6 wk of the start of the mating season) compared with reliabilities of 0.39 and 0.45 for CR42 only or the current 5-trait Australian model. Subsequently, we used the first eigenvector of a principal component analysis with udder texture, bone quality, angularity, and body condition score to calculate an energy status indicator trait. The inclusion of the energy status indicator trait composite in a multitrait index with CVI, LL, CFS, FNRR, and CR42 achieved a 12-point increase in fertility breeding value reliability (i.e., increased by 30%; up to 0.72 points of reliability), whereas a lower increase in reliability (4 points, i.e., increased by 10%) was obtained by including angularity, foot angle, and pin set in the index. In situations when a limited number of daughters have been phenotyped for CR42, including type data for sires increased reliabilities compared with when type data were omitted. However, sires with more than 80 daughters with CR42 records achieved reliability estimates close to 80% on average, and there did not appear to be a benefit from having daughters with type records. The cost of phenotyping to obtain such reliabilities (assuming a cost of AU$14 per cow with type data and AU$5 per cow with pregnancy diagnosed) is lower if more pregnancy data are collected in preference to type data. That is, efforts to increase the reliability of fertility EBV are most cost effective when directed at obtaining a larger number of pregnancy tests. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  13. Comments on "The Six Questions that Do Not Go Away".

    PubMed

    Mahmood, N

    1991-01-01

    Comments on Krotki's article on the 6 recurring questions pertaining to Pakistani data enumeration problems are presented. There is agreement that data anomalies persist and valid points were made about the demographic information problems. The irregularities in age distribution are explained as misreporting and under and over enumeration that is prevalent in Pakistan and many other countries. The proportion 15 years is where it should be with an average growth rate of 3%. The higher numbers in the 5-9 year age group over the 0-4 year age group are due to heaping or misreporting among the 5-9 year group and underreporting in the 0-4 year group. Awareness of the problem is appropriate, but new ways are needed to remedy the situation. Illiteracy of females should be addressed by asking how to bring those not attending school into the system and to improve the supply and demand issues related to education. What may appear to erratic and inconsistent family planning information still provides a clear picture that there is high fertility and low contraceptive use. The important question is why fertility transition is delayed and why contraceptive levels are so low. Are there supply constraints, or are children in demand and women unprepared to adopt fertility control measures? Guidelines for improving census data collection are needed in order to minimize the errors and omissions pointed out by Krotki. Why and how the role of the Pakistan Household Survey Capability Programme can improve census data collection and reliability needs to be spelled out. THe data situation is not as dismal as displayed by Krotki if one considers that many other countries, even developed ones, have the same data collection problems.

  14. Cryopreservation of Indian red jungle fowl (Gallus gallus murghi) semen with polyvinylpyrrolidone.

    PubMed

    Rakha, Bushra Allah; Ansari, Muhammad Sajjad; Akhter, Shamim; Zafar, Zartasha; Hussain, Iftikhar; Santiago-Moreno, Julian; Blesbois, Elisabeth

    2017-10-01

    The Indian red jungle fowl is a sub-species of the genus Gallus native to South Asia; facing high risk of extinction in its native habitat. During cryopreservation, permeable cryoprotectants like glycerol are usually employed and we previously showed encouraging results with 20% glycerol. Because bird spermatozoa contain very little intracellular water, the possibility of replacing an internal cryoprotectant by an external one is opened. In the present study, we tested the replacement of internal cryoprotectant glycerol by the external cryoprotectant Polyvinylpyrrolidone (PVP). PVP is a non-permeable cryoprotectant and keeps the sperm in glassy state both in cooling and warming stages without making ice crystallization within the sperm cell. We evaluated the effect of various levels of polyvinylpyrrolidone (PVP) on Indian red jungle fowl semen quality and fertility outcomes. The qualifying semen ejaculates collected from eight mature cocks were pooled, divided into five aliquots, diluted (37 °C) with red fowl semen extender having PVP [0% (control) 4% (w/v), 6% (w/v), 8% (w/v) and 10% (w/v)]. Diluted semen was cryopreserved and stored in liquid nitrogen. The whole experiment was repeated/replicated for five times independently. Sperm motility, plasma membrane integrity, viability and acrosome integrity were recorded highest (P < 0.05) with 6% PVP at post-dilution, cooling, equilibration and freeze-thawing. Higher (P < 0.05) no. of fertile eggs, fertility, no. of hatched chicks, percent hatch and hatchability was recorded with 6% PVP compared to control. It is concluded that 6% PVP maintained better post-taw quality and fertility of Indian red jungle fowl spermatozoa than glycerol and can be used in routine practice avoiding the contraceptive effects of glycerol. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Field-quantified responses of tropical rainforest aboveground productivity to increasing CO2 and climatic stress, 1997-2009

    NASA Astrophysics Data System (ADS)

    Clark, Deborah A.; Clark, David B.; Oberbauer, Steven F.

    2013-06-01

    A directional change in tropical-forest productivity, a large component in the global carbon budget, would affect the rate of increase in atmospheric carbon dioxide ([CO2]). One current hypothesis is that "CO2 fertilization" has been increasing tropical forest productivity. Some lines of evidence instead suggest climate-driven productivity declines. Relevant direct field observations remain extremely limited for this biome. Using a unique long-term record of annual field measurements, we assessed annual aboveground net primary productivity (ANPP) and its relation to climatic factors and [CO2] in a neotropical rainforest through 1997-2009. Over this 12 year period, annual productivity did not increase, as would be expected with a dominant CO2 fertilization effect. Instead, the negative responses of ANPP components to climatic stress far exceeded the small positive responses associated with increasing [CO2]. Annual aboveground biomass production was well explained (73%) by the independent negative effects of increasing minimum temperatures and greater dry-season water stress. The long-term records enable a first field-based estimate of the [CO2] response of tropical forest ANPP: 5.24 g m-2 yr-1 yr-1 (the summed [CO2]-associated increases in two of the four production components; the largest component, leaf litterfall, showed no [CO2] association). If confirmed by longer data series, such a small response from a fertile tropical rainforest would indicate that current global models overestimate the benefits from CO2 fertilization for this biome, where most forests' poorer nutrient status more strongly constrains productivity responses to increasing [CO2]. Given the rapidly intensifying warming across tropical regions, tropical forest productivity could sharply decline through coming decades.

  16. Comparison of rhizosphere properties as affected by different Bt- and non-Bt-cotton (Gossypium hirsutum L.) genotypes and fertilization.

    PubMed

    Ahamd, Maqshoof; Abbasi, Waleed Mumtaz; Jamil, Moazzam; Iqbal, Muhammad; Hussain, Azhar; Akhtar, Muhammad Fakhar-U-Zaman; Nazli, Farheen

    2017-06-01

    Incorporation of genetically modified crops in the cropping system raises the need for studying the effect of these crops on the soil ecosystem. The current study aimed to compare the effect of Bacillus thuringiensis (Bt)- and non-Bt-cotton (Gossypium hirsutum L.) genotypes on rhizosphere properties under fertilized and unfertilized soil conditions. One non-Bt-cotton (IUB 75) and four Bt-cotton varieties (IUB-222, MM-58, IUB-13, FH-142) were sown in a Randomized Complete Block Design (RCBD) in a factorial fashion with three replications under unfertilized (T1) and fertilized (T2 at NPK 310-170-110 kg ha -1 ) soil conditions. The culturable soil bacterial population was recorded at flowering, boll opening, and harvesting stages, while other rhizosphere biological and chemical properties were recorded at harvesting. Results revealed that Bt-cotton genotypes IUB-222 and FH-142 showed significantly higher rhizosphere total nitrogen, NH 4 + -N, available phosphorus, and available potassium. Total organic carbon and microbial biomass carbon was also maximum in the rhizosphere of IUB-222 under fertilized conditions. Similarly, bacterial population (CFU g -1 ) at flowering stage and at harvesting was significantly higher in the rhizosphere of IUB-222 as compared to non-Bt- (IUB-75) and other Bt-cotton genotypes under same growth conditions. It showed that Bt genotypes can help in maintaining soil macronutrients (total nitrogen, available phosphorus, and available potassium) under proper nutrient management. Moreover, Bt-cotton genotypes seem to strengthen certain biological properties of the soil, thus increasing the growth and yield capability, maintaining available nutrients in the soil as compared to non-Bt cotton, while no harmful effects of Bt cotton on soil properties was detected.

  17. Amebiasis

    MedlinePlus

    ... that have crowded living conditions and poor sanitation. Africa, Mexico, parts of South America, and India have major health problems due to this condition. The parasite may spread: Through food or water contaminated with stools Through fertilizer made of human ...

  18. Ovarian stimulation leads to shorter stature in childhood.

    PubMed

    Savage, Tim; Peek, John C; Robinson, Elizabeth M; Green, Mark P; Miles, Harriet L; Mouat, Fran; Hofman, Paul L; Cutfield, Wayne S

    2012-10-01

    We aimed to determine whether children conceived with ovarian stimulation alone (OS(A)) would differ phenotypically and biochemically from naturally conceived children of fertile and subfertile parents. Healthy pre-pubertal children aged 3-10 years, born at term, after singleton pregnancies were recruited in Auckland (New Zealand) and were allocated into three groups: (i) children conceived following OS(A) and naturally conceived children of (ii) subfertile and (iii) fertile parents. Anthropometric, endocrine and metabolic parameters were recorded. Children's heights and body mass index (BMI) were expressed as standard deviation scores (SDS) and corrected for genetic potential (i.e. parental height or BMI). Three hundred fifty-two children were studied: 84 OS(A) subjects and 268 naturally conceived controls consisting of 54 children of subfertile parents and 214 children of fertile parents. Children of subfertile and fertile parents did not differ in measured outcomes. Overall, OS(A) children were shorter than children of both subfertile (SDS: -0.08 ± 0.09 versus 0.32 ± 0.07; P= 0.001) and fertile (SDS: -0.08 ± 0.09 versus 0.45 ± 0.10; P= 0.004) parents when corrected for genetic height potential. OS(A) boys were shorter than boys of subfertile (SDS:-0.18 ± 0.14 versus 0.42 ± 0.16; P= 0.03) and fertile (SDS: -0.18 ± 0.14 versus 0.35 ± 0.08; P= 0.01) parents. There was also a trend towards OS(A) girls being shorter than girls of subfertile parents (P= 0.06), but not significantly shorter than those of fertile parents (P= 0.17). OS(A) children also had a lower corrected BMISDS than children of subfertile (SDS-0.90 ± 0.15 versus -0.37 ± 0.17; P= 0.06) and fertile (-0.90 ± 0.15 versus -0.34 ± 0.10; P= 0.008) parents. Among metabolic parameters, fasting glucose was lower in OS(A) children than that in children of fertile parents (4.62 ± 0.07 versus 4.81 ± 0.04; P= 0.006). Conception after OS(A) was associated with shorter stature, particularly in boys, compared with naturally conceived children of fertile and subfertile parents.

  19. A Bayesian network model for predicting pregnancy after in vitro fertilization.

    PubMed

    Corani, G; Magli, C; Giusti, A; Gianaroli, L; Gambardella, L M

    2013-11-01

    We present a Bayesian network model for predicting the outcome of in vitro fertilization (IVF). The problem is characterized by a particular missingness process; we propose a simple but effective averaging approach which improves parameter estimates compared to the traditional MAP estimation. We present results with generated data and the analysis of a real data set. Moreover, we assess by means of a simulation study the effectiveness of the model in supporting the selection of the embryos to be transferred. © 2013 Elsevier Ltd. All rights reserved.

  20. Prior to Conception: The Role of an Acupuncture Protocol in Improving Women's Reproductive Functioning Assessed by a Pilot Pragmatic Randomised Controlled Trial

    PubMed Central

    Cochrane, Suzanne; Smith, Caroline A.; Possamai-Inesedy, Alphia; Bensoussan, Alan

    2016-01-01

    The global average of couples with fertility problems is 9%. Assisted reproductive technologies are often inaccessible. Evidence points to acupuncture offering an opportunity to promote natural fertility. This study asked whether providing a multiphasic fertility acupuncture protocol to women with sub/infertility would increase their awareness of fertility and achieve normalisation of their menstrual cycle compared with a lifestyle control. In a pragmatic randomised controlled trial sub/infertile women were offered an intervention of acupuncture and lifestyle modification or lifestyle modification only. There was a statistically significant increase in fertility awareness in the acupuncture group (86.4%, 19) compared to 40% (n = 8) of the lifestyle only participants (Relative Risk (RR) 2.38, 95% confidence interval (CI) of 1.25, 4.50), with an adjusted p value of 0.011. Changes in menstrual regularity were not statistically significant. There was no statistical difference in the pregnancy rate with seven women (adjusted p = 0.992) achieving pregnancy during the course of the study intervention. Those receiving the acupuncture conceived within an average of 5.5 weeks compared to 10.67 weeks for the lifestyle only group (p = 0.422). The acupuncture protocol tested influenced women who received it compared to women who used lifestyle modification alone: their fertility awareness and wellbeing increased, and those who conceived did so in half the time. PMID:27242910

  1. Live birth after artificial oocyte activation using a ready-to-use ionophore: a prospective multicentre study.

    PubMed

    Ebner, Thomas; Montag, Markus; Montag, M; Van der Ven, K; Van der Ven, H; Ebner, T; Shebl, O; Oppelt, P; Hirchenhain, J; Krüssel, J; Maxrath, B; Gnoth, C; Friol, K; Tigges, J; Wünsch, E; Luckhaus, J; Beerkotte, A; Weiss, D; Grunwald, K; Struller, D; Etien, C

    2015-04-01

    Artificial oocyte activation has been proposed as a suitable means to overcome the problem of failed or impaired fertilization after intracytoplasmic sperm injection (ICSI). In a multicentre setting artificial oocyte activation was applied to 101 patients who were diagnosed with fertilization abnormalities (e.g. less than 50% fertilized oocytes) in a previous conventional ICSI cycle. Female gametes were activated for 15 min immediately after ICSI using a ready-to-use Ca(2+)-ionophore solution (A23187). Fertilization, pregnancy and live birth rates were compared with the preceding cycle without activation. The fertilization rate of 48% in the study cycles was significantly higher compared with the 25% in the control cycles (P < 0.001). Further splitting of the historical control group into failed (0%), low (1-30%) and moderate fertilization rate (31-50%) showed that all groups significantly benefitted (P < 0.001) in the ionophore cycle. Fewer patients had their embryo transfer cancelled compared with their previous treatments (1/101 versus 15/101). In total, 99% of the patients had an improved outcome with A23187 application resulting in a 28% live birth rate (35 babies). These data suggest that artificial oocyte activation using a ready-to-use compound is an efficient method. Copyright © 2014 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

  2. Fertility outcome and information on fertility issues in individuals with different forms of disorders of sex development: findings from the dsd-LIFE study.

    PubMed

    Słowikowska-Hilczer, Jolanta; Hirschberg, Angelica Lindén; Claahsen-van der Grinten, Hedi; Reisch, Nicole; Bouvattier, Claire; Thyen, Ute; Cohen Kettenis, Peggy; Roehle, Robert; Köhler, Birgit; Nordenström, Anna

    2017-11-01

    To investigate fertility outcome in individuals with different forms of disorders of sex development (DSD), if assisted reproductive technology (ART) was used, and the patients' satisfaction with the information they had received. A cross-sectional multicenter study, dsd-LIFE. Not applicable. A total of 1,040 patients aged ≥16 years with different DSD diagnoses participated. A web-based questionnaire was filled out by all participants. The participants could chose to take part in somatic investigations including ultrasonography. Information on partner, number of children, ART, adoption and step-children, general health, presence of gonads and uterus, current education and economic situation, received information on fertility issues, and satisfaction with the information, was collected. In the total cohort, mean age 32 years, 33% lived with a partner, but only 14% reported having at least one child including 7% with ART, 4% adopted. Only 3.5% of the total cohort had been able to reproduce without ART, most frequently women with congenital adrenal hyperplasia, and only 0.7% of participants with other diagnoses. Of the participants, 72% had received information on fertility, but 17% were not satisfied with the information. Fertility outcome is significantly reduced in all types of DSD; however, fertility potential should be assessed individually. The satisfaction with how fertility problems have been discussed can be improved. The care of patients with DSD is complex, should be individualized, and new treatment possibilities incorporated. A close collaboration in multidisciplinary teams is therefore essential to improve the situation for individuals with DSD. Copyright © 2017 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  3. Short-term experiments in using digestate products as substitutes for mineral (N) fertilizer: Agronomic performance, odours, and ammonia emission impacts.

    PubMed

    Riva, C; Orzi, V; Carozzi, M; Acutis, M; Boccasile, G; Lonati, S; Tambone, F; D'Imporzano, G; Adani, F

    2016-03-15

    Anaerobic digestion produces a biologically stable and high-value fertilizer product, the digestate, which can be used as an alternative to mineral fertilizers on crops. However, misuse of digestate can lead to annoyance for the public (odours) and to environmental problems such as nitrate leaching and ammonia emissions into the air. Full field experimental data are needed to support the use of digestate in agriculture, promoting its correct management. In this work, short-term experiments were performed to substitute mineral N fertilizers (urea) with digestate and products derived from it to the crop silage maize. Digestate and the liquid fraction of digestate were applied to soil at pre-sowing and as topdressing fertilizers in comparison with urea, both by surface application and subsurface injection during the cropping seasons 2012 and 2013. After each fertilizer application, both odours and ammonia emissions were measured, giving data about digestate and derived products' impacts. The AD products could substitute for urea without reducing crop yields, apart from the surface application of AD-derived fertilizers. Digestate and derived products, because of high biological stability acquired during the AD, had greatly reduced olfactometry impact, above all when they were injected into soils (82-88% less odours than the untreated biomass, i.e. cattle slurry). Ammonia emission data indicated, as expected, that the correct use of digestate and derived products required their injection into the soil avoiding, ammonia volatilization into the air and preserving fertilizer value. Sub-surface injection allowed ammonia emissions to be reduced by 69% and 77% compared with surface application during the 2012 and 2013 campaigns. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. Use of fertility drugs and risk of ovarian cancer: results from a U.S.-based case-control study.

    PubMed

    Kurta, Michelle L; Moysich, Kirsten B; Weissfeld, Joel L; Youk, Ada O; Bunker, Clareann H; Edwards, Robert P; Modugno, Francesmary; Ness, Roberta B; Diergaarde, Brenda

    2012-08-01

    Previous studies examining associations between use of fertility drugs and ovarian cancer risk have provided conflicting results. We used data from a large case-control study to determine whether fertility drug use significantly impacts ovarian cancer risk when taking into account parity, gravidity, and cause of infertility. Data from the Hormones and Ovarian Cancer Prediction (HOPE) study were used (902 cases, 1,802 controls). Medical and reproductive histories were collected via in-person interviews. Logistic regression was used to calculate ORs and 95% confidence intervals (CI). Models were adjusted for age, race, education, age at menarche, parity, oral contraceptive use, breastfeeding, talc use, tubal ligation, and family history of breast/ovarian cancer. Ever use of fertility drugs was not significantly associated with ovarian cancer within the total HOPE population (OR, 0.93; 95% CI, 0.65-1.35) or among women who reported seeking medical attention for infertility (OR, 0.87; 95% CI, 0.54-1.40). We did observe a statistically significant increased risk of ovarian cancer for ever use of fertility drugs among women who, despite seeking medical attention for problems getting pregnant, remained nulligravid (OR, 3.13; 95% CI, 1.01-9.67). These results provide further evidence that fertility drug use does not significantly contribute to ovarian cancer risk among the majority of women; however, women who despite infertility evaluation and fertility drug use remain nulligravid, may have an elevated risk for ovarian cancer. Our results suggest that fertility drug use does not significantly contribute to overall risk of ovarian cancer when adjusting for known confounding factors. ©2012 AACR.

  5. Dynamics of fertility impairment in childhood brain tumour survivors.

    PubMed

    Pfitzer, C; Chen, C-M; Wessel, T; Keil, T; Sörgel, A; Langer, T; Steinmann, D; Borgmann-Staudt, A

    2014-10-01

    Fertility impairment and recovery after chemo- and radiotherapy have been reported in both male and female childhood cancer survivors, but little is known about the dynamics. Our aim, therefore, was to describe the development of fertility impairment and possible recovery in childhood brain tumour survivors. In this longitudinal study, we included 144 survivors, who were treated in two German paediatric oncology centres between 2000 and 2005. Fertility parameters were retrieved from medical records up to 12 years after diagnosis. Participants with age ≥13 years and formerly cranial irradiation ≥30 Gray (n = 23), including 83 % (n = 19) with craniospinal irradiation ≥30 Gray, had a higher median FSH concentration compared to 29 patients without chemoradiotherapy: 8.3 IU/l (IQR 6.5-11.2) versus 4.1 IU/l (IQR 3.2-5.1) 2 years after initial treatment; 8.9 IU/l (IQR 8.5-10.8) versus 4.2 IU/l (IQR 2.4-6.7) after 8 years; and 7.1 IU/l (IQR 6.7-7.7) versus 3.5 IU/l (IQR 2.8-4.2) after 10 years. Altogether, 11/65 women reported the occurrence of amenorrhoea 6.0 years (range 1-10) after diagnosis. Five of these women later developed a regular menstrual cycle without hormone replacement therapy. Patients' chance of recovery from fertility impairment was increased with time since diagnosis (p = 0.074). Signs of fertility impairment such as amenorrhoea and elevated FSH levels were observed at variable time points between 1 and 12 years after chemoradiotherapy. Decreasing FSH levels were observed 1-7 years after elevation and were interpreted either as an atrophy of the pituitary gland or as recovery from fertility impairment.

  6. The contribution of multiple pregnancies from overseas fertility treatment to obstetric services in a Western Australian tertiary obstetric hospital.

    PubMed

    Waller, Kylie Anne; Dickinson, Jan E; Hart, Roger J

    2017-08-01

    Increasingly couples are travelling overseas to access assisted reproductive technology, known as cross border reproductive care, although the incidence, pregnancy outcomes and healthcare costs are unknown. To determine obstetric and neonatal outcomes for multiple pregnancies conceived through fertility treatment overseas, and estimate cost of these pregnancies to the health system. Retrospective study of women receiving care for a multiple gestation between July 2013 and June 2015 at Western Australia's sole tertiary obstetric hospital, where conception was by overseas fertility treatment. Obstetric and neonatal outcomes were recorded and cost estimates calculated. Of 11 710 births, 422 were multiple pregnancies. Thirty-seven pregnancies were conceived with fertility treatment, with 11 (29.7%) conceived overseas. Median antenatal clinic attendances, ultrasound examinations, and fetal assessments for the overseas fertility cases were six, 10, and nine, respectively. The gestational age at delivery ranged from 30 to 38 weeks (median 34 + 1). Median neonatal admission duration was 18 days (range 0-47). Cost for obstetric care was estimated between $170 000 and $216 000, and cost of neonatal care was estimated as $810 000, giving a combined total cost of between $980 000 and $1 026 000. At the sole tertiary obstetric centre in WA, approximately one-third of all multiple pregnancies conceived with fertility treatment resulted from treatment overseas. The Australian healthcare cost for these 11 women and their infants exceeded $1 000 000. This study suggests that overseas fertility treatment has a significant health-related cost to the mother and infant, and the local healthcare system. © 2017 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.

  7. Protein expression pattern of PAWP in bull spermatozoa is associated with sperm quality and fertility following artificial insemination.

    PubMed

    Kennedy, Chelsey E; Krieger, Kari Beth; Sutovsky, Miriam; Xu, Wei; Vargovič, Peter; Didion, Bradley A; Ellersieck, Mark R; Hennessy, Madison E; Verstegen, John; Oko, Richard; Sutovsky, Peter

    2014-05-01

    Post-acrosomal WW-domain binding protein (PAWP) is a signaling molecule located in the post-acrosomal sheath (PAS) of mammalian spermatozoa. We hypothesized that the proper integration of PAWP in the sperm PAS is reflective of bull-sperm quality and fertility. Cryopreserved semen samples from 298 sires of acceptable, but varied, fertility used in artificial insemination services were analyzed using immunofluorescence microscopy and flow cytometry for PAWP protein. In normal spermatozoa, PAWP fluorescence formed a regular band around the proximal PAS. Anomalies of PAWP labeling in defective spermatozoa were reflected in flow cytometry by varied intensities of PAWP-induced fluorescence. Distinct sperm phenotypes were also identified, including morphologically normal and some defective spermatozoa with moderate levels of PAWP; grossly defective spermatozoa with low/no PAWP; and defective spermatozoa with high PAWP. Analysis by ImageStream flow cytometry confirmed the prevalence of abnormal sperm phenotypes in the spermatozoa with abnormal PAWP content. Live/dead staining and video recording showed that some abnormal spermatozoa are viable and capable of progressive motility. Conventional flow-cytometric measurements of PAWP correlated significantly with semen quality and fertility parameters that reflect the sires' artificial insemination fertility, including secondary sperm morphology, conception rate, non-return rate, and residual value. A multiplex, flow-cytometric test detecting PAWP, aggresomes (ubiquitinated protein aggregates), and acrosomal integrity (peanut-agglutinin-lectin labeling) had a predictive value for conception rate, as demonstrated by step-wise regression analysis. We conclude that PAWP correlates with semen/fertility parameters used in the cattle artificial insemination industry, making PAWP a potential biomarker of bull fertility. © 2014 Wiley Periodicals, Inc.

  8. Effect of timing of joint application of hydroquinone and dicyandiamide on nitrous oxide emission from irrigated lowland rice paddy field.

    PubMed

    Li, Xianglan; Zhang, Guangbin; Xu, Hua; Cai, Zucong; Yagi, Kazuyuki

    2009-06-01

    A field experiment was conducted to study the effect of timing of joint application of urease inhibitor hydroquinone (HQ) and nitrification inhibitor dicyandiamide (DCD) on N(2)O emission from irrigated lowland rice paddy field. Four treatments including Treatment CK (the control with urea alone), HQ/DCD-1 (application of HQ and DCD together with fertilizer before transplanting), HQ/DCD-2 (HQ and DCD with fertilizer at tillering stage) and HQ/DCD-3 (HQ and DCD with fertilizer at panicle initiation stage) were designed and implemented separately during rice growth period. Seasonal peaks of N(2)O flux occurred during midseason drainage and significant negative correlation between N(2)O flux and water layer depth was observed (r=-0.69 to -0.75, P<0.01). Mean N(2)O flux was the highest in the control with urea alone, while joint addition of HQ and DCD with urea lowered mean N(2)O flux considerably (P<0.05). Total N(2)O emission during rice growth season in Treatment CK, HQ/DCD-1, HQ/DCD-2 and HQ/DCD-3 was 3.90, 2.98, 1.73 and 3.23kgN(2)O-N ha(-1), respectively. Application of HQ and DCD together with basal fertilizer, tillering fertilizer and panicle initiation fertilizer decreased the total N(2)O emission by 24%, 56% and 17%, respectively, while increased grain yield by 10%, 18% and 6%, respectively. Effect of application of inhibitors on N(2)O emission during the continuous period from incorporation of HQ and DCD to rice harvest was also studied, where results indicating that the highest inhibiting efficiency of inhibitors on N(2)O emission was recorded when HQ and DCD applied with fertilizer at tillering stage.

  9. Drug use among men with unfulfilled wish to father children: a retrospective analysis and discussion of specific drug classes.

    PubMed

    Pompe, Sina V; Strobach, Dorothea; Stief, Christian G; Becker, Armin J; Trottmann, Matthias

    2016-06-01

    Male infertility is a multifactorial state. Among other risk factors, drugs can adversely affect male fertility and male sexual function. In a retrospective study we aimed to analyse how many involuntarily childless men seeking fertility evaluation consume drugs, which drugs and if these are potentially affecting male reproductive function. We retrospectively identified involuntarily childless men presenting for fertility evaluation at an andrologic outpatient department from 2011 to 2014. Medical records were searched for current drug use, age, diseases affecting male fertility, and number and kind of drugs. Drugs were classified according to their Anatomical Therapeutic Chemical code. Adverse drug reactions on male sexual function and fertility were searched in two independent literature sources. Drug use was documented for 244 of 522 patients (46.7%). The patients' mean age was 37.7 ± 8.7; the total number of drug intakes was 554 (mean 2.3 ± 1.9), corresponding to 201 different drugs. The most often involved Anatomical Therapeutic Chemical groups were nervous system (N), alimentary tract/metabolism (A), cardiovascular (C), and respiratory system (R) (n = 277; 50.0%). Fertility impairment was reported for 15.9%, and adverse drug reactions on male sexual function were found for 51.2% of all identified drugs. Underreporting of consumed drugs was likely, especially for non-prescription drugs. A high percentage of involuntarily childless men is taking drugs that can potentially influence male reproductive function. As drug intake represents a modifiable risk factor, fertility evaluation requires a comprehensive medication review including prescription and non-prescription drugs. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  10. 40 CFR 80.1401 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... of pressure that is produced through the conversion of organic matter. Only biogas that is used as... crops, crop residue, or livestock, or records of purchases for land treatments such as fertilizer, weed... ecologically sensitive forestland. (5) Biomass (organic matter that is available on a renewable or recurring...

  11. Effect of Nitrogen Fertilization and Harvest Time on Steviol Glycosides, Flavonoid Composition, and Antioxidant Properties in Stevia rebaudiana Bertoni.

    PubMed

    Tavarini, Silvia; Sgherri, Cristina; Ranieri, Anna Maria; Angelini, Luciana G

    2015-08-12

    This work investigated the effect of nitrogen fertilization and harvest time on the flavonoid composition and antioxidant properties of Stevia rebaudiana leaves. At the same time, changes in stevioside (Stev) and rebaudioside A (RebA) contents were recorded. A pot trial under open air conditions was set up, testing five N rates and three harvest times. The results showed that, by using an adequate N rate and choosing an appropriate harvest time, it was possible to significantly increase and optimize the bioactive compound levels. In particular, higher RebA, RebA/Stev ratio, total phenols and flavonoids, luteolin-7-O-glucoside, and apigenin-7-O-glucoside levels and antioxidant capacity were recorded by supplying 150 kg N ha(-1). Reduced or increased N availability in comparison with N150 had no consistent effect on Stevia phytochemicals content. Significant correlations were also found between stevioside and some of the flavonoids, indicating a possible role of flavonoids in the stevioside metabolic pathway, which deserves more investigations.

  12. Penis Disorders

    MedlinePlus

    Problems with the penis can cause pain and affect a man's sexual function and fertility. Penis disorders include Erectile dysfunction - inability to get or ... not go away Peyronie's disease - bending of the penis during an erection due to a hard lump ...

  13. Cross-cultural comparison of fertility specific quality of life in German, Hungarian and Jordanian couples attending a fertility center.

    PubMed

    Sexty, Réka E; Hamadneh, Jehan; Rösner, Sabine; Strowitzki, Thomas; Ditzen, Beate; Toth, Bettina; Wischmann, Tewes

    2016-02-24

    Only a few studies have reported cross-cultural comparisons regarding psychosocial consequences of infertility. Differences between societies with different cultural backgrounds were revealed and seemed to be based on the importance of pronatalism. Our aim was to measure cross-cultural differences in fertility specific quality of life of infertile couples in Germany, Hungary and Jordan who attend a fertility center in a cross-sectional study. A cross-sectional study was conducted in one fertility clinic in Germany, in five fertility clinics in Hungary and in one fertility clinic in Jordan. Overall 750 couples (252 couples in Jordan, 246 couples in Germany and 252 couples in Hungary) attending the first medical infertility consultation were asked to fill out our questionnaire set. Fertility specific quality of life (FertiQoL) and sociodemographic differences were measured between couples from three countries. Jordanian couples had the shortest relationship (5.8 ± 4.3 yrs.), though they reported the longest duration of child wish (4.2 ± 3.6 yrs.) and fertility treatments (3.0 ± 3.3 yrs.). The proportion of high education was considerably higher in Jordanian women and men (60 % and 66 %, respectively) compared to the other two samples. First, marked cross-country differences were obtained on Emotional, Mind/Body and Relational subscales of the FertiQoL, indicating that Jordanian couples reported poorer fertility-related quality of life than Germans and Hungarians (p < 0.001). After controlling for the sociodemographic and medical variables, a significant difference only in the Emotional domain was observed (p < 0.001). The study revealed only a few cultural based differences in fertility specific quality of life between the couples of the three countries. Thus, infertility counselors should pay attention to psychosocial problems rooted in individual sociocultural aspects of the infertile couple regardless of cultural stereotypes. Further studies should identify sociocultural factors within different subgroups of infertile patients instead of focusing different societies as a whole because intra-cultural psychosocial differences in experiencing infertility seem to be more important for the individual patient than intercultural differences.

  14. Role of Marine Biology in Glacial-Interglacial CO2 Cycles

    NASA Astrophysics Data System (ADS)

    Kohfeld, Karen E.; Le Quéré, Corinne; Harrison, Sandy P.; Anderson, Robert F.

    2005-04-01

    It has been hypothesized that changes in the marine biological pump caused a major portion of the glacial reduction of atmospheric carbon dioxide by 80 to 100 parts per million through increased iron fertilization of marine plankton, increased ocean nutrient content or utilization, or shifts in dominant plankton types. We analyze sedimentary records of marine productivity at the peak and the middle of the last glacial cycle and show that neither changes in nutrient utilization in the Southern Ocean nor shifts in plankton dominance explain the CO2 drawdown. Iron fertilization and associated mechanisms can be responsible for no more than half the observed drawdown.

  15. Potash

    USGS Publications Warehouse

    Jasinski, S.M.

    2010-01-01

    In 2009, the world potash market deteriorated as world demand, trade and sales fell dramatically. After potash prices reached record high levels in 2008, many consumers and dealers delayed purchases until the price dropped. Potash prices did not recede as quickly as other fertilizer commodities, which led to further increases in potash stocks. In 2009, high stocks and lower demand contributed to a drop in world production of more than 30 percent from 2008. Nearly all major producers reported lower production in 2009, as many mines were idle in the first half of the year and world production was at 50 percent of capacity. Consumption of both fertilizers and industrial uses dropped significantly in 2009.

  16. Fertilizer consumption trend in developing countries vs. developed countries.

    PubMed

    Motesharezadeh, Babak; Etesami, Hassan; Bagheri-Novair, Sepideh; Amirmokri, Hormoz

    2017-03-01

    The study of the chemical fertilizer consumption in different countries provides basal data for the decision-making of fertilizer production and for the environmental impact assessment of fertilizer application. Hence, the aim of this research was to study and compare the trend of the chemical fertilizer consumption from 1980 to 2012 in Iran, Turkey, Japan, Germany, France, and the USA. For this purpose, various indices such as application rates (kg ha -1 ) of N, P, and K, arable land, and total fertilizer consumption were analysed. Results showed that the application rates of nutrients (N-P 2 O 5 -K 2 O) in Iran, Turkey, Japan, Germany, France, and the USA in 2012 were 100-42-7, 100-42-7, 100-94-60, 100-17-25, 100-13-38, and 100-33-35, respectively. The lowest and highest area under production were observed in Japan with 4.0 million ha (0.033 ha/person) and in the USA with 155.0 million ha (0.51 ha/person) during 2008-2015, respectively. In addition, the highest and lowest application rates of net nutrient consumption were recorded in France and Germany (285 and 285 kg ha -1 ) and in Iran (66 kg ha -1 ), respectively. Overall, the average net consumption of fertilizers in the studied countries in three recent decades (million tonnes) decreased in the order: the USA (19.282) > France (4.601) > Germany (3.302) > Turkey (1.825) > Japan (1.604) > Iran (1.130). Regarding an estimated 9.2 billion people by 2050, the balanced consumption of nutrients (N-P 2 O 5 -K 2 O) and the principles of optimal consumption of fertilizers are keys for achieving the increased food production, food security, and environmental conservation.

  17. Classification scheme for phenomenological universalities in growth problems in physics and other sciences.

    PubMed

    Castorina, P; Delsanto, P P; Guiot, C

    2006-05-12

    A classification in universality classes of broad categories of phenomenologies, belonging to physics and other disciplines, may be very useful for a cross fertilization among them and for the purpose of pattern recognition and interpretation of experimental data. We present here a simple scheme for the classification of nonlinear growth problems. The success of the scheme in predicting and characterizing the well known Gompertz, West, and logistic models, suggests to us the study of a hitherto unexplored class of nonlinear growth problems.

  18. County-level estimates of nitrogen and phosphorus from commercial fertilizer for the Conterminous United States, 1987–2006

    USGS Publications Warehouse

    Gronberg, Jo Ann M.; Spahr, Norman E.

    2012-01-01

    The U.S. Geological Survey’s National Water-Quality Assessment program requires nutrient input for analysis of the national and regional assessment of water quality. Detailed information on nutrient inputs to the environment are needed to understand and address the many serious problems that arise from excess nutrients in the streams and groundwater of the Nation. This report updates estimated county-level farm and nonfarm nitrogen and phosphorus input from commercial fertilizer sales for the conterminous United States for 1987 through 2006. Estimates were calculated from the Association of American Plant Food Control Officials fertilizer sales data, Census of Agriculture fertilizer expenditures, and U.S. Census Bureau county population. A previous national approach for deriving farm and nonfarm fertilizer nutrient estimates was evaluated, and a revised method for selecting representative states to calculate national farm and nonfarm proportions was developed. A national approach was used to estimate farm and nonfarm fertilizer inputs because not all states distinguish between farm and nonfarm use, and the quality of fertilizer reporting varies from year to year. For states that distinguish between farm and nonfarm use, the spatial distribution of the ratios of nonfarm-to-total fertilizer estimates for nitrogen and phosphorus calculated using the national-based farm and nonfarm proportions were similar to the spatial distribution of the ratios generated using state-based farm and nonfarm proportions. In addition, the relative highs and lows in the temporal distribution of farm and nonfarm nitrogen and phosphorus input at the state level were maintained—the periods of high and low usage coincide between national- and state-based values. With a few exceptions, nonfarm nitrogen estimates were found to be reasonable when compared to the amounts that would result if the lawn application rates recommended by state and university agricultural agencies were used. Also, states with higher nonfarm-to-total fertilizer ratios for nitrogen and phosphorus tended to have higher urban land-use percentages.

  19. Fertility and hatchability in RIR and WL breeds as functionally modified by crossing them in alternate sex combinations (Gallus domesticus).

    PubMed

    Zelleke, G; Moudgal, R P; Asmare, A

    2005-02-01

    (1) Four breeding groups of Rhode Island Red and White Leghorn domestic fowl (RIR (female) x RIR (male), RIR (female) x WL (male), WL (female) x RIR (male) and WL (female) x WL (male)) were compared for fertility, hatchability, and their post-insemination sustainability, egg weight loss during incubation and uncovered yolk in abdominal cavity of dead in shell in order to understand the problems associated with the RIR breed in these respects. (2) Crossing RIR (female) with WL (male) or in reverse sex combinations did not improve fertility in comparison to pure RIR chickens and all these groups were less fertile than the pure WL. (3) Unlike fertility, hatchability in RIR improved with the change to either sex partner of the WL breed but the WL (female) x RIR (male) combination was similar to the pure WL (97.72 and 97.12%, respectively). In contrast, crossing RIR (female) with WL (male) resulted in an improvement (86.67%) as compared to pure RIR (76.67%) but still lower than the pure WL and WL (female) x RIR (male) cross. (4) Egg weight loss during incubation was more (20.16%) in pure RIR as compared to RIR (female) x WL (male) (17.13%), followed by WL (female) x RIR (male) (10.28%) and pure WL (9.57%). (5) There were more dead-in-shell embryos with yolks outside their abdominal cavity in pure RIR and their crosses as compared to pure WL breeds. (6) Fertility was sustained for longer in WL than other combinations with post-artificial insemination using constant number of spermatozoa. Fertility after a week of insemination tended to decrease more rapidly than hatchability on a fertile egg basis. (7) It is concluded that both sexes are responsible for the poor fertility in RIR but the female is responsible for poor hatchability and this poor performance is mainly due to greater egg weight loss during incubation.

  20. Possible mechanism of polyspermy block in human oocytes observed by time-lapse cinematography.

    PubMed

    Mio, Yasuyuki; Iwata, Kyoko; Yumoto, Keitaro; Kai, Yoshiteru; Sargant, Haruka C; Mizoguchi, Chizuru; Ueda, Minako; Tsuchie, Yuka; Imajo, Akifumi; Iba, Yumiko; Nishikori, Kyoko

    2012-09-01

    To analyze the fertilization process related to polyspermy block in human oocytes using an in vitro culturing system for time-lapse cinematography. We had 122 oocytes donated for this study from couples that provided informed consent. We recorded human oocytes at 2,000 to 2,800 frames every 10 s during the fertilization process and thereafter every 2 min using a new in vitro culture system originally developed by the authors for time-lapse cinematography. We displayed 30 frames per second for analysis of the polyspermy block during fertilization. Three oocytes showed the leading and following sperm within the zona pellucida in the same microscopic field. The dynamic images obtained during the fertilization process using this new system revealed that once a leading sperm penetrated the zona pellucida and attached to the oocyte membrane, a following sperm was arrested from further penetration into the zona pellucida within 10 s. The present results strongly suggest the existence of a novel mechanism of polyspermy block that takes place at the zona pellucida immediately after fertilization. These findings are clearly different from previous mechanisms describing polyspermy block as the oocyte membrane block to sperm penetration and the zona reaction. The finding presented herein thus represents a novel discovery about the highly complicated polyspermy block mechanism occurring in human oocytes.

  1. Bacteria in combination with fertilizers promote root and shoot growth of maize in saline-sodic soil.

    PubMed

    Zafar-Ul-Hye, Muhammad; Farooq, Hafiz Muhammad; Hussain, Mubshar

    2015-03-01

    Salinity is the leading abiotic stress hampering maize ( Zea mays L.) growth throughout the world, especially in Pakistan. During salinity stress, the endogenous ethylene level in plants increases, which retards proper root growth and consequent shoot growth of the plants. However, certain bacteria contain the enzyme 1-aminocyclopropane-1-carboxylate (ACC) deaminase, which converts 1-aminocyclopropane-1-carboxylic acid (an immediate precursor of ethylene biosynthesis in higher plants) into ammonia and α-ketobutyrate instead of ethylene. In the present study, two Pseudomonas bacterial strains containing ACC-deaminase were tested separately and in combinations with mineral fertilizers to determine their potential to minimize/undo the effects of salinity on maize plants grown under saline-sodic field conditions. The data recorded at 30, 50 and 70 days after sowing revealed that both the Pseudomonas bacterial strains improved root and shoot length, root and shoot fresh weight, and root and shoot dry weight up to 34, 43, 35, 71, 55 and 68%, respectively, when applied without chemical fertilizers: these parameter were enhanced up to 108, 95, 100, 131, 100 and 198%, respectively, when the strains were applied along with chemical fertilizers. It can be concluded that ACC-deaminase Pseudomonas bacterial strains applied alone and in conjunction with mineral fertilizers improved the root and shoot growth of maize seedlings grown in saline-sodic soil.

  2. Bacteria in combination with fertilizers promote root and shoot growth of maize in saline-sodic soil

    PubMed Central

    Zafar-ul-Hye, Muhammad; Farooq, Hafiz Muhammad; Hussain, Mubshar

    2015-01-01

    Salinity is the leading abiotic stress hampering maize ( Zea mays L.) growth throughout the world, especially in Pakistan. During salinity stress, the endogenous ethylene level in plants increases, which retards proper root growth and consequent shoot growth of the plants. However, certain bacteria contain the enzyme 1-aminocyclopropane-1-carboxylate (ACC) deaminase, which converts 1-aminocyclopropane-1-carboxylic acid (an immediate precursor of ethylene biosynthesis in higher plants) into ammonia and α-ketobutyrate instead of ethylene. In the present study, two Pseudomonas bacterial strains containing ACC-deaminase were tested separately and in combinations with mineral fertilizers to determine their potential to minimize/undo the effects of salinity on maize plants grown under saline-sodic field conditions. The data recorded at 30, 50 and 70 days after sowing revealed that both the Pseudomonas bacterial strains improved root and shoot length, root and shoot fresh weight, and root and shoot dry weight up to 34, 43, 35, 71, 55 and 68%, respectively, when applied without chemical fertilizers: these parameter were enhanced up to 108, 95, 100, 131, 100 and 198%, respectively, when the strains were applied along with chemical fertilizers. It can be concluded that ACC-deaminase Pseudomonas bacterial strains applied alone and in conjunction with mineral fertilizers improved the root and shoot growth of maize seedlings grown in saline-sodic soil. PMID:26221093

  3. RESEARCH RECORDS AND THE RESOLUTION OF MISCONDUCT ALLEGATIONS AT RESEARCH UNIVERSITIES

    PubMed Central

    WILSON, KENNETH; SCHREIER, ALAN; GRIFFIN, ANGEL; RESNIK, DAVID

    2014-01-01

    Accurate record keeping is an important part of the responsible conduct of research. However, there is very little empirical research on scientific record keeping. No one knows the incidence of serious problems with research records, the types of problems that occur, nor their consequences. In this study, we examined the role of research records in the resolution of misconduct allegations as a useful barometer for the incidence and types of problems that occur with records. We interviewed Research Integrity Officers (RIOs) at 90 major research universities and conducted focus groups with active research faculty. RIOs reported problems with research records in 38% of the 553 investigations they conducted. Severe problems with research records often prevented completion of investigations while problems that are more typical lengthened them by 2 to 3 weeks. Five types of poor record keeping practices accounted for 75% of the problems with incomplete/inadequate records being the most common (30%). The focus groups concurred with the findings from the interviews with RIOs, stressed the importance of the research group leader in setting and maintaining record practices, and offered additional insights. While university officials and faculty members have suspected for many years that there are serious problems with research record keeping, our study provides empirical evidence for this belief. By documenting some of the problems with record keeping in university-based research, the results of our study provide information that will be useful for policy development at academic institutions. PMID:17847607

  4. Research records and the resolution of misconduct allegations at research universities.

    PubMed

    Wilson, Kenneth; Schreier, Alan; Griffin, Angel; Resnik, David

    2007-01-01

    Accurate record keeping is an important part of the responsible conduct of research. However, there is very little empirical research on scientific record keeping. No one knows the incidence of serious problems with research records, the types of problems that occur, nor their consequences. In this study, we examined the role of research records in the resolution of misconduct allegations as a useful barometer for the incidence and types of problems that occur with records. We interviewed Research Integrity Officers (RIOs) at 90 major research universities and conducted focus groups with active research faculty. RIOs reported problems with research records in 38% of the 553 investigations they conducted. Severe problems with research records often prevented completion of investigations while problems that are more typical lengthened them by 2 to 3 weeks. Five types of poor record keeping practices accounted for 75 % of the problems with incomplete/inadequate records being the most common (30%). The focus groups concurred with the findings from the interviews with RIOs, stressed the importance of the research group leader in setting and maintaining record practices, and offered additional insights. While university officials and faculty members have suspected for many years that there are serious problems with research record keeping, our study provides empirical evidence for this belief. By documenting some of the problems with record keeping in university-based research, the results of our study provide information that will be useful for policy development at academic institutions.

  5. Profit from Problem Solving.

    ERIC Educational Resources Information Center

    Schrader, Clifford L.

    1993-01-01

    Describes a chemistry classroom project of forming a company to acquire 10,000 pounds of zinc sulfate monohydrate from a company that wanted to dispose of it. The zinc was eventually sold to an agricultural company for use in fertilizer. (PR)

  6. New medical risks affecting obstetrics after implementation of the two-child policy in China.

    PubMed

    Li, Qiang; Deng, Dongrui

    2017-12-01

    China recently instituted a two-child policy in response to its aging population, declining workforce and demographic dividend, and the need to develop asocial economy. Additionally, women generally delay having a second child because of the overwhelming pressure in their lives. With the improvements in assisted fertility technologies in recent years, the number of elderly women attempting to bear children has increased. The quality of woman's eggs and a man's sperm declined dramatically with increasing age, leading to an increased risk of pregnancy-related complications among older women. Therefore, the types of fertility problems experienced by elderly females must be provided with considerable attention by obstetricians. This commentary article focuses on the medical problems faced by older second-child pregnant women. This work discusses their increased rates of infertility, spontaneous abortion, fetal malformation, gestational diabetes, cesarean section, placenta previa, postpartum hemorrhage, postpartum depression, and hypertensive disorders, which complicate pregnancy.

  7. Endometrial immune markers are potential predictors of normal fertility and pregnancy after in vitro fertilization.

    PubMed

    Kofod, Louise; Lindhard, Anette; Bzorek, Michael; Eriksen, Jens Ole; Larsen, Lise Grupe; Hviid, Thomas Vauvert F

    2017-09-01

    Elucidating immune mechanisms in the endometrium, which lead to the success of implantation and pregnancy, is important in reproductive medicine. Studies of immune cell abundance have shown conflicting results, and the expression and importance of HLA class Ib proteins in pre-implantation endometrium have not yet been investigated. The study population consisted of four subgroups: a hydrosalpinx, a salpingectomy, an unexplained infertility, and a fertile control group. Endometrial samples were collected during the implantation window. Immune markers (CD56 + and CD16 + cells, FoxP3 + Tregs, HLA-G, HLA-F) were quantified in the samples. The outcome of the subsequent IVF treatment was recorded. Increased CD56 + uNK cells and high HLA-G expression served as predictor for successful pregnancy outcome. HLA-F expression was positively correlated with uNK cells, being indirectly predictive for achieving pregnancy. Endometrial uNK cell abundance in the pre-implantation endometrium seems to be important for normal fertility and pregnancy success, and they may be used as clinical markers to predict implantation success in IVF. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  8. Fertility and obstetric outcome after conservative management of placenta accreta.

    PubMed

    Provansal, Magali; Courbiere, Blandine; Agostini, Aubert; D'Ercole, Claude; Boubli, Léon; Bretelle, Florence

    2010-05-01

    To determine the fertility and obstetric outcomes after conservative management of placenta accreta. A retrospective observational cohort study of all identified cases of placenta accreta from 1993 to 2007 in 2 tertiary university hospitals in France. For patients treated conservatively, maternal and fetal morbidity, reproductive function, fertility, and subsequent pregnancies were recorded. During the study period, 46 patients were treated by conservative management; 6 patients underwent a secondary hysterectomy. Of the remaining 40 patients, 35 were followed up for a median of 65 months (range 18-156 months). Patients resumed their menstrual cycles after a median of 130 days (range 48-176 days). Menses were irregular in 11 patients (31%), but none had amenorrhea. Twelve of the 14 patients desiring another pregnancy achieved a total of 15 pregnancies; 2 patients had recurrent placenta accreta. Five spontaneous abortions and 1 termination of pregnancy occurred during the first trimester. The median term at delivery was 37 weeks (range, 35-40 weeks). Four patients delivered prematurely. Conservative management of placenta accreta can preserve fertility, although the risk of recurrent placenta accreta appears to be high. Copyright 2010 Elsevier Ireland Ltd. All rights reserved.

  9. Roxithromycin treatment of mouse chlamydial salpingitis and protective effect on fertility.

    PubMed Central

    Zana, J; Muffat-Joly, M; Thomas, D; Orfila, J; Salat-Baroux, J; Pocidalo, J J

    1991-01-01

    We used a mouse model of acute chlamydial salpingitis to evaluate the efficacy of roxithromycin in preventing irreversible inflammatory damage leading to tubal infertility. Female C3H/He mice were genitally inoculated with a human strain of Chlamydia trachomatis and then treated with roxithromycin glutamate subcutaneously. Treatment was initiated either 7 or 10 days postinfection (p.i.) and continued for 7 days at a dosage of 50 or 100 mg/kg of body weight per 24 h. The course of the disease was monitored serologically, bacteriologically, and histologically. At the end of the treatment, the mice were encaged with males and their reproductive capacity was recorded over a 19-week period. The protective effect of roxithromycin was assessed in terms of fertility parameters in comparison with values for noninfected control mice. When treatment was initiated on day 7 p.i. and given in twice-daily 25-mg/kg doses, all the mice remained fertile and the total number of offspring was similar to that of sham-infected mice (17.3 +/- 3.3 versus 17.2 +/- 2.3). When treatment was initiated on day 10 p.i. and given in a single daily dose of 50 or 100 mg/kg, 90 and 70% of the mice, respectively, remained fertile; however, in terms of total offspring, fertility was lower in the group treated with the lower dose (5.6 +/- 1.4 versus 13.0 +/- 3.8). Roxithromycin was found to be effective against C. trachomatis in the mouse genital tract, but fertility was only partially preserved when the time between infection and treatment was prolonged. Images PMID:2039193

  10. Effect of caffeine on motility and vitality of sperm and in vitro fertilization of outbreed mouse in T6 and M16 media

    PubMed Central

    Nabavi, Narges; Todehdehghan, Fatemeh; Shiravi, Abdollhossein

    2013-01-01

    Background: Caffeine increases the CAMP production that stimulates spermatozoa movement. Caffeine is also used for induction of in vitro acrosome reaction in mammalian spermatozoa, an important step in achieving fertilization. Objective: The aim of this study was to assess the effect of caffeine on sperm's motility, vitality and laboratory fertilization rates in mouse in two T6 and M16 media. Materials and Methods: Epididymal mouse sperms were collected and treated by caffine in T6 and M16 media and their motility and vitality rates were evaluated. The pretreated sperms were added to oocytes in T6 and M16 media with and without caffeine and fertilization rates were recorded after 24 hours incubation. Results: Sperm's motility (81.7±1.67%) and vitality (88.7±1.33%) rates and percentage of fertilized oocytes (67.52±8.16%) in T6 medium plus caffeine compare to control group have increased and shown significant differences at p≤0.01. While the percentages of these parameters in M16 medium supplemented with caffeine were 68.3±6.01%, 78±6.11%, and 42.6±12.96 respectively and in comparison to control group (M16 without caffeine) have not shown significant differences. Conclusion: Addition of caffeine to T6 medium promotes the sperm's motility and vitality and enhances fertilization and early in vitro development of mouse embryos. This article extracted from M.Sc. thesis. (Narges Navabi) PMID:24639814

  11. [Follow-up of children conceived by assisted reproductive technologies].

    PubMed

    Bouillon, C; Fauque, P

    2013-05-01

    Since the birth of the first baby conceived by in vitro fertilization (IVF) 30 years ago (Louise Brown in 1978), there has been a rapid and constant increase in the number of couples using assisted reproductive technologies (ART). Around four million of children have been born from couples experiencing fertility problems, through the use of ART, comprising roughly 2-3 % of all births in Europe and U.S. That highlights that these modes of fertilization are now well assumed by our societies. However, several questions on health of these children remain to be elucidated. As evoked in this review, even if methodological limitations exist, numerous studies have reported increased risks of birth defects, like prematurity, foetal hypotrophy, neonatal complications, congenital malformations and epigenetic diseases among ART-conceived children as compared to naturally conceived children. Nowadays, it is difficult to determine if these increased risks found in ART infants are a consequence of the ART procedures or are inherent to the infertility problems per se. However, absolute risks remain moderate and reassuring as well as the data on follow-up into infancy and early childhood. Nevertheless, because the effects may occur at the adulthood, there is a need for long-term follow-up of children born after ART. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  12. Psychiatric disorders in women with fertility problems: results from a large Danish register-based cohort study.

    PubMed

    Baldur-Felskov, B; Kjaer, S K; Albieri, V; Steding-Jessen, M; Kjaer, T; Johansen, C; Dalton, S O; Jensen, A

    2013-03-01

    Do women who don't succeed in giving birth after an infertility evaluation have a higher risk of psychiatric disorders compared with women who do? The results indicated that being unsuccessful in giving birth after an infertility evaluation could be an important risk factor for psychiatric disorders. Several studies have investigated the association between fertility treatment and psychological distress, but the results from these studies show substantial variation and lack of homogeneity that may be due to methodological limitations. A retrospective cohort study was designed using data from a cohort of 98 320 Danish women evaluated for fertility problems during 1973-2008 and linked to several Danish population-based registries. All women were followed from the date of first infertility evaluation until date of hospitalization for the psychiatric disorder in question, date of emigration, date of death or 31 December 2008, whichever occurred first. Owing to the precise linkage between the infertility cohort and the Danish population-based registries, using the unique Danish personal identification number, virtually no women were lost to follow-up. Information on reproductive status for all women in the infertility cohort was obtained by linkage to the Danish Medical Birth Registry. A total of 53 547 (54.5%) women gave birth after the initial infertility evaluation, whereas 44 773 (45.5%) women did not gave birth after the evaluation. To determine psychiatric disorders diagnosed in the women after enrolment in the infertility cohort, the cohort was linked to the Danish Psychiatric Central Registry. A total of 4633 women were hospitalized for a psychiatric disorder. The Cox proportional hazard regression model was applied to estimate hazard ratios (HRs) and corresponding 95% confidence intervals (CIs) for the association between parity status after the initial infertility evaluation and risk of hospitalization for various groups of psychiatric disorders, including 'all mental disorders' and six main discharge subgroups labelled: 'alcohol and intoxicant abuse', 'schizophrenia and psychoses', 'affective disorders', 'anxiety, adjustment and obsessive compulsive disorders', 'eating disorder' and 'other mental disorders'. The incidence rate for all mental disorders was 393 cases per 100 000 person-years among women who did not succeed in giving birth after the infertility evaluation but only 353 cases per 100 000 person-years among women who succeeded in giving birth after the infertility evaluation. Women not giving birth after the infertility evaluation had an increased risk of hospitalization for all mental disorders (HR 1.17, 95% CI 1.11; 1.25), alcohol and intoxicant abuse (HR 2.02, 95% CI 1.69; 2.41), schizophrenia and psychoses (HR 1.46, 95% CI 1.17; 1.82) and other mental disorders (HR 1.42, 95% CI 1.27; 1.58) compared with women who gave birth after the infertility evaluation. In contrast, the risk of affective disorders (HR 0.90, 95% CI 0.81; 0.99) was decreased among women not giving birth after the infertility evaluation. Finally, the risk of anxiety, adjustment and obsessive compulsive disorders (HR 1.07, 95% CI 0.97; 1.17) as well as of eating disorders (HR 1.40, 95% CI 0.88; 2.22) was not significantly affected by parity status after the infertility evaluation. As only psychiatric conditions warranting hospitalization could be included in the present study, the true incidence of all psychiatric disorders among women with fertility problems is likely to be somewhat underestimated. Furthermore, since detailed information on fertility treatment was not available for all cohort members the association between different modalities of assisted reproductive techniques and risk of psychiatric disorders was not assessed. Clinicians and other healthcare personnel involved in diagnosis and treatment of women with fertility problems should be aware of the potential risk modification of psychiatric disorders associated with unsuccessful fertility treatment. Hence, our results may point to new aspects of follow-up of women with fertility problems who are unsuccessful in giving birth in order to prevent or identify and treat these possible psychological side effects. The study was supported by the Danish Cancer Society (award number: 96 222 54). All authors report no conflicts of interest.

  13. [A research review on "fertile islands" of soils under shrub canopy in arid and semi-arid regions].

    PubMed

    Chen, Guangsheng; Zeng, Dehui; Chen, Fusheng; Fan, Zhiping; Geng, Haiping

    2003-12-01

    Due to the inclemency of climate and soil conditions and the intense disturbance of human beings, the soil resources heterogeneity in arid and semi-arid grassland ecosystems worldwide was gradually increased during the last century. The interaction between soil heterogeneity and shrubs induced the autogenic development of "fertile islands" and the increasing spread of shrubs in the grassland ecosystems. The development of "fertile islands" around individual shrubs could change the vegetation composition and structure, as well as the distribution patterns of soil resources, and thus, reinforced the changes of the ecosystem function and structure from a relative stable grassland ecosystem to a quasi-stable shrubland ecosystem. The study of "fertile islands" phenomenon would help us to understand the causes, consequences and processes of desertification in arid and semi-arid areas. In this paper, the causes of "fertile islands", its study methods and significance and its relationship with shrub spreading as well as the responses of vegetation to it were summarized. The problems which might occur in the study of this phenomenon were also pointed out. Our aim was to offer some references to the study of land desertification processes and vegetation restoration in the arid and semi-arid regions.

  14. Should access to fertility treatment be determined by female body mass index?

    PubMed

    Pandey, S; Maheshwari, A; Bhattacharya, S

    2010-04-01

    Resource allocation towards fertility treatment has been extensively debated in countries where fertility treatment is publicly-funded. Medical, social and ethical aspects have been evaluated prior to allocation of resources. Analysis of cost-effectiveness, risks and benefits and poor success rates have led to calls of restricting fertility treatment to obese women. In this debate article, we critically appraise the evidence underlying this issue and highlight the problems with such a policy. Poor success rate of treatment is unsubstantiated as there is insufficient evidence to link high body mass index (BMI) to reduction in live birth. Obstetric complications have a linear relationship with BMI but are significantly influenced by maternal age. The same is true for miscarriage rates which are influenced by the confounding factors of polycystic ovary syndrome and age. Studies have shown that the direct costs per live birth are no greater for overweight and obese women. With changing demographics over half the reproductive-age population is overweight or obese. Restricting fertility treatment on the grounds of BMI would cause stigmatization and lead to inequity, feelings of injustice and social tension as affluent women manage to bypass these draconian restrictions. Time lost and poor success of conventional weight loss strategies would jeopardize the chances of conception for many women.

  15. Male Infertility during Antihypertensive Therapy: Are We Addressing Correctly The Problem?

    PubMed

    Laganà, Antonio Simone; Vitale, Salvatore Giovanni; Iaconianni, Paola; Gatti, Simona; Padula, Francesco

    2016-01-01

    Male fertility significantly decreased in the last 50 years, as showed in several studies reporting a reduction of sperm counts per ml in the seminal fluid. Several "acute" pharmacological treatments, as antibiotics, could cause subclinical and temporary reduction of male fertility; conversely, long-term medical treatment may severely affect male fertility, although this effect could be considered transient in most of the cases. Thus, nowadays, several long-term pharmacological treatments may represent a clinical challenge. The association between several kind of antihypertensive drugs and reduction of male fertility has been showed in the mouse model, although the modification(s) which may alter this fine-regulated machinery are still far to be elucidated. Furthermore, well-designed observational studies and randomized controlled trials are needed to accurately define this association in human model, meaning a narrative overview synthesizing the findings of literature retrieved from searches of computerized databases. We strongly solicit future human studies (both observational and randomized clinical trials) on large cohorts with adequate statistical power which may clarify this possible association and the effects (reversible or permanent) of each drug. Furthermore, we suggest a close collaboration between general practitioners, cardiologists, and andrologists in order to choose the most appropriate antihypertensive therapy considering also patient's reproductive desire and possible risk for his fertility.

  16. [Is an act of human love the in vitro fertilization? A proposal ethical analysis].

    PubMed

    García Sánchez, Emilio

    2014-01-01

    Since 1978, when the first test tube baby, Louis Brown, was born, thousands of children have been born every year through in vitro fertilization. Many families keep attending fertility clinics in order to receive some treatment for their infertility problems and have a child. Children born in this way are worthy human beings. Their parents love them and devote themselves to their children admirably, showing real parental love. However, does this loving kindness justify, from an ethical point of view, any way of desiring and having a son or daughter? Is it really an act of human love to long for a child and satisfy this desire using artificial methods? Is it equally human and worthy to wish them choosing in vitro fertilization than to wish them through an intimate and loving relationship, in which the child emerges as a result of interpersonal donation? I answer these questions by analyzing the ethics proposal formulated by Rhonheimer and Carrasco de Paula. In short, only the intimate and loving sexual union between a man and a woman -as long as it is unconditional love- may be the dignity cause of the existence of a human being. And such union and unconditional requirement are absent in vitro fertilization.

  17. Discrimination of the effects on zebrafish reproduction from pollutants in drinking water via female, via male and/or via fecundation water.

    PubMed

    Martínez-Sales, M; García-Ximénez, F; Espinós, F J

    2016-08-01

    The lack of preventive policy legislation and the low removal rate of organic pollutants in conventional potabilization treatments lead to some of them being present in drinking water. The problem arises because some of these substances have detrimental effects on human reproduction health, via females, via males or even both. In this work, we established the zebrafish as a bioindicator of these types of substances with the goal of discriminating the effects through three different pathways: male, female or water where the fertilization took place. For this purpose, four parameters were analysed: fertility rate, hatching rate and survival and abnormalities rates. So, for each parameter two groups were formed, according to whether adult males or females were reared in bottled spring water (Z) or tap water (B) and if the in vitro fertilization took place in water Z or B. Results revealed a decline in the fertility and hatching rate in water B, due to a water effect. The most plausible explanation could be the presence of substances which affect the micropyle and chorion. Moreover, a decrease in the fertility rate due to an effect over the female was also observed, but in this case by an alteration of the oocyte quality.

  18. [Body condition and metabolic stability as the basis for high milk yield and undisturbed fertility in dairy cows--a contribution for deduction of reference values].

    PubMed

    Staufenbiel, R; Arndt, G; Schröder, U; Gelfert, C C

    2004-05-01

    The target of this study was to describe the interactions between body condition and various descriptors of yield and fertility. It was aimed to identify an optimal conditional range to be used in herd management which combines high milk yield with acceptable fertility traits and general health. For this purpose, backfat thickness was measured by ultrasound at 46111 dairy cows on 78 different farms and was subsequently related to production variables. Negative energy balance is getting more intense and prolonged with increasing milk yield. However a conditional nadir below 10 mm leads to decreased milk production. To reach a high production level without an increasing incidence of health disorders, conditional nadir should not decline below 13 mm backfat thickness on herd average. Lower value only lead to negligibly higher milk yield but cause a distinctively higher risk of fertility problems and culling. High herd yields do not have to be at expense of reproduction performance and can be achieved without extreme body condition losses. An efficient herd management can offset depression in fertility, which commonly is combined with increasing milk yield. A standard curve for backfat thickness throughout lactation is suggested to be used in dairy herd management.

  19. First records of a field experiment on fertilizer effects on methane emission from rice fields in Hunan-Province (PR China)

    NASA Astrophysics Data System (ADS)

    Wassmann, R.; Wang, M. X.; Shangguan, X. J.; Xie, X. L.; Shen, R. X.; Wang, Y. S.; Papen, H.; Rennenberg, H.; Seiler, W.

    Fertilizer effects on methane emission from Chinese rice fields were investigated by a praxis-oriented approach applying balanced amendments of N, P and K. The data set obtained covered the emission rates of app. one month in early rice and one month in late rice 1991. An intercomparison between the 4 treatments showed pronounced differences in the magnitudes of methane emission rates. The combined organic/mineral fertilizer application, commonly used as local farming practice, resulted in relatively high seasonal averages of methane emission rates (26.5 mg CH4 m-2 h-1 in early rice and 50.1 mg CH4 m-2 h-1 in late rice). The lowest emission rates were observed in the plot with pure mineral fertilization (6.5 mg CH4 m-2 h-1 in early rice and 14.3 mg CH4 m-2 h-1 in late rice). Pure organic fertilizers by unfermented substances yielded the highest methane emission rates of all field trials (38.6 mg CH4 m-2 h-1 in early rice and 56.2 CH4 m-2 h-1 in late rice). The fertilization with fermented material derived from biogas generators resulted in substantially lower emission rates than the other trials with organic amendments, the seasonal averages corresponded to 15.9 mg CH4 m-2 h-1 (early rice) and 22.5 mg CH4 m-2 h-1 (late rice). Interpretation of the results can be obtained from the different potentials of these fertilizers for methane production. Based on this concept the different methane emission rates observed with organic/mineral, pure mineral and pure unfermented-organic fertilizers could directly be attributed to the different quantities of organic matter incorporated into the soil. The low methane emission from the plot treated with fermented material could be explained by a depletion of potential methane precursors resulting from the preceding fermentation. The results of this investigation provide evidence that the extensive use of specific chemical fertilizers and the application of sludge from the operation of biogas generators could lead to a net reduction of the methane emission from rice fields.

  20. On the role of mid-infrared predicted phenotypes in fertility and health dairy breeding programs.

    PubMed

    Bastin, C; Théron, L; Lainé, A; Gengler, N

    2016-05-01

    Fertility and health traits are of prime importance in dairy breeding programs. However, these traits are generally complex, difficult to record, and lowly heritable (<0.10), thereby hampering genetic improvement in disease resistance and fertility. Hence, indicators are useful in the prediction of genetic merit for fertility and health traits as long as they are easier to measure than direct fitness traits, heritable, and genetically correlated. Considering that changes in (fine) milk composition over a lactation reflect the physiological status of the cow, mid-infrared (MIR) analysis of milk opens the door to a wide range of potential indicator traits of fertility and health. Previous studies investigated the phenotypic and genetic relationships between fertility and MIR-predicted phenotypes, most being related to negative postpartum energy balance and body fat mobilization (e.g., fat:protein ratio, urea, fatty acids profile). Results showed that a combination of various fatty acid traits (e.g., C18:1 cis-9 and C10:0) could be used to improve fertility. Furthermore, occurrence of (sub)clinical ketosis has been related to milk-based phenotypes such as fat:protein ratio, fatty acids, and ketone bodies. Hence, MIR-predicted acetone and β-hydroxybutyrate contents in milk could be useful for breeding cows less susceptible to ketosis. Although studies investigating the genetic association among mastitis and MIR-predicted phenotypes are scarce, a wide range of traits, potentially predicted by MIR spectrometry, are worthy of consideration. These include traits related to the disease response of the cow (e.g., lactoferrin), reduced secretory activity (e.g., casein), and the alteration of the blood-milk barrier (e.g., minerals). Moreover, direct MIR prediction of fertility and health traits should be further considered. To conclude, MIR-predicted phenotypes have a role to play in the improvement of dairy cow fertility and health. However, further studies are warranted to (1) grasp underlying associations among MIR-predicted indicator and fitness traits, (2) estimate the genetic parameters, and (3) include these traits in broader breeding strategies. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  1. [Recent population policy measures in Belgium, especially with respect to fertility].

    PubMed

    Bosman, E

    1985-01-01

    Policy measures affecting fertility, recently adopted in Belgium, are reviewed. The author notes that although responsibility for population matters has been delegated to the respective language groups, the responsibility for family law, divorce, abortion, social security, taxation, and labor policy remains a national responsibility. There are currently no measures in these areas adopted primarily for demographic reasons. Differences between the approaches taken by the French- and Dutch-speaking communities are noted. The author suggests that the French-speaking community has focused on problems relating to contraception and abortion, and the Dutch-speaking community has emphasized social welfare and family policy

  2. On Reproductive Work in Spain: Transnational Adoption, Egg Donation, Surrogacy.

    PubMed

    Marre, Diana; San Román, Beatriz; Guerra, Diana

    2018-01-01

    Spain's plummeting fertility since the late twentieth century may seem to reflect a waning desire for children. Nevertheless, reproductive disappointments resulting from gender inequalities cause many Spanish women to postpone motherhood and experience age-related fertility problems. For them, creating a family often becomes possible only through the reproductive labor of other women. Our analysis of transnational adoption, egg donation, and surrogacy in Spain shows how anonymity and altruism play out in these three strategies, with implications for the valuation of women's reproductive work and relationships among reproductive providers, intermediaries, recipients, and the resulting children.

  3. Genome-wide mapping of loci explaining variance in scrotal circumference in Nellore cattle

    USDA-ARS?s Scientific Manuscript database

    The reproductive performance of bulls has a high impact on the beef cattle industry. Scrotal circumference (SC) is the most recorded reproductive trait in beef herds, and is used as a major selection criterion to improve precocity and fertility. The characterization of genomic regions affecting SC...

  4. An international overview of the recording and use of functional traits in dairy cattle breeding and management

    USDA-ARS?s Scientific Manuscript database

    An important component in the development of sustainable dairy production systems is the maintenance of cow health and functionality. Genetic selection has resulted in substantial increases in cow productivity over the past fifty years, but health and fertility are increasingly important determinant...

  5. Decreasing Fertilizer use by Optimizing Plant-microbe Interactions for Sustainable Supply of Nitrogen for Bioenergy Crops

    NASA Astrophysics Data System (ADS)

    Schicklberger, M. F.; Huang, J.; Felix, P.; Pettenato, A.; Chakraborty, R.

    2013-12-01

    Nitrogen (N) is an essential component of DNA and proteins and consequently a key element of life. N often is limited in plants, affecting plant growth and productivity. To alleviate this problem, tremendous amounts of N-fertilizer is used, which comes at a high economic price and heavy energy demand. In addition, N-fertilizer also significantly contributes to rising atmospheric greenhouse gas concentrations. Therefore, the addition of fertilizer to overcome N limitation is highly undesirable. To explore reduction in fertilizer use our research focuses on optimizing the interaction between plants and diazotrophic bacteria, which could provide adequate amounts of N to the host-plant. Therefore we investigated the diversity of microbes associated with Tobacco (Nicotiana tabacum) and Switchgrass (Panicum virgatum), considered as potential energy crop for bioenergy production. Several bacterial isolates with representatives from Alphaproteobacteria, Gammaproteobacteria, Actinobacteria, Bacteriodetes and Bacilli were obtained from the roots, leaves, rhizoplane and rhizosphere of these plants. Majority of these isolates grew best with simple sugars and small organic acids. As shown by PCR amplification of nifH, several of these isolates are potential N2-fixing bacteria. We investigated diazotrophs for their response to elevated temperature and salinity (two common climate change induced stresses found on marginal lands), their N2-fixing ability, and their response to root exudates (which drive microbial colonization of the plant). Together this understanding is necessary for the development of eco-friendly, economically sustainable energy crops by decreasing their dependency on fertilizer.

  6. In situ nitrogen mineralization, nitrification, and ammonia volatilization in maize field fertilized with urea in Huanghuaihai region of northern China.

    PubMed

    Zhang, Xuelin; Wang, Qun; Xu, Jun; Gilliam, Frank S; Tremblay, Nicolas; Li, Chaohai

    2015-01-01

    Nitrogen (N) fertilization potentially affects soil N mineralization and leaching, and can enhance NH3 volatilization, thus impacting crop production. A fertilizer experiment with five levels of N addition (0, 79, 147, 215 and 375 kg N ha(-1)) was performed in 2009 and 2010 in a maize field in Huanghuaihai region, China, where > 300 kg N ha(-1) has been routinely applied to soil during maize growth period of 120 days. Responses of net N mineralization, inorganic N flux (0-10 cm), NH3 volatilization, and maize yield to N fertilization were measured. During the growth period, net N mineralization and nitrification varied seasonally, with higher rates occurring in August and coinciding with the R1 stage of maize growth. Soil NO3(-)-N contributed to more than 60% of inorganic N flux during maize growth. Cumulative NH3 volatilization increased with N additions, with total NH3 volatilization during maize growth accounting for about 4% of added N. Relative to the control, mean maize yield in the fertilizer treatments increased by 17% and 20% in 2009 and 2010, respectively. However, grain yield, aboveground biomass, and plant N accumulation did not increase with added N at levels > 215 kg N ha(-1). These results suggest that the current N rate of 300 kg N ha(-1) is not only excessive, but also reduces fertilizer efficacy and may contribute to environmental problems such as global warming and eutrophication of ground water and streams.

  7. Pregnancy Problems? Boost the Chance of Having a Baby

    MedlinePlus

    ... pregnant, a woman’s body must first release an egg from one of her ovaries, a process called ... then has to join with, or “fertilize,” the egg. The egg must then travel through a passageway ...

  8. Semen analysis (image)

    MedlinePlus

    The sperm count test is performed if a man's fertility is in question. It is helpful in determining if there is a problem in sperm production or quality of the sperm as a cause of infertility. The test may also be used after ...

  9. Infertility in resource-constrained settings: moving towards amelioration.

    PubMed

    Hammarberg, Karin; Kirkman, Maggie

    2013-02-01

    It is often presumed that infertility is not a problem in resource-poor areas where fertility rates are high. This is challenged by consistent evidence that the consequences of childlessness are very severe in low-income countries, particularly for women. In these settings, childless women are frequently stigmatized, isolated, ostracized, disinherited and neglected by the family and local community. This may result in physical and psychological abuse, polygamy and even suicide. Attitudes among people in high-income countries towards provision of infertility care in low-income countries have mostly been either dismissive or indifferent as it is argued that scarce healthcare resources should be directed towards reducing fertility and restricting population growth. However, recognition of the plight of infertile couples in low-income settings is growing. One of the United Nation's Millennium Development Goals was for universal access to reproductive health care by 2015, and WHO has recommended that infertility be considered a global health problem and stated the need for adaptation of assisted reproductive technology in low-resource countries. This paper challenges the construct that infertility is not a serious problem in resource-constrained settings and argues that there is a need for infertility care, including affordable assisted reproduction treatment, in these settings. It is often presumed that infertility is not a problem in densely populated, resource-poor areas where fertility rates are high. This presumption is challenged by consistent evidence that the consequences of childlessness are very severe in low-income countries, particularly for women. In these settings, childless women are frequently stigmatized, isolated, ostracized, disinherited and neglected by the family and local community. This may result in physical and psychological abuse, polygamy and even suicide. Because many families in low-income countries depend on children for economic survival, childlessness and having fewer children than the number identified as appropriate are social and public health matters, not only medical problems. Attitudes among people in high-income countries towards provision of infertility care in low-income countries have mostly been either dismissive or indifferent as it is argued that scarce healthcare resources and family planning activities should be directed towards reducing fertility and restricting population growth. However, recognition of the plight of infertile couples in low-income settings is growing. One of the United Nation's Millennium Development Goals was for universal access to reproductive health care by 2015, and WHO has recommended that infertility be considered a global health problem and stated the need for adaptation of assisted reproduction technology in low-resource countries. In this paper, we challenge the construct that infertility is not a serious problem in resource-constrained settings and argue that there is a need for infertility care, including affordable assisted reproduction treatment, in these settings. Copyright © 2012 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

  10. Fertility in Adult Bitches Previously Treated with a 4.7 mg Subcutaneous Deslorelin Implant.

    PubMed

    Borges, P; Fontaine, E; Maenhoudt, C; Payan-Carreira, R; Santos, N; Leblond, E; Fontaine, C; Fontbonne, A

    2015-12-01

    The absence of fertility problems in male dogs after a single treatment with deslorelin acetate (Suprelorin(®)) is well acknowledged. However, reports on the application of deslorelin in the bitch and information concerning fertility after implant treatment are still limited. In this retrospective study, data concerning induced and spontaneous oestruses of 39 bitches from 17 breeds, treated with deslorelin acetate implants (4.7 mg Suprelorin(®), Virbac, France), were retrieved to assess post-treatment fertility (ovulation rate, pregnancy rate and litter size). Animals were grouped according to treatment characteristics: group 1 (Gr1) - females submitted to oestrus induction, showing natural oestruses afterwards (n = 19); group 2 (Gr2) - females re-implanted with 4.7 mg deslorelin acetate to re-induce oestrus, showing subsequent spontaneous post-implant oestruses (n = 7); and group 3 (Gr3) - females submitted to a 4.7 mg deslorelin acetate implant for oestrus suppression, evaluated at subsequent spontaneous post-implant oestruses (n = 13). Comparison of fertility traits between induced and post-treatment spontaneous oestruses in Gr1 and Gr2 (short treatments), or between spontaneous oestruses after long-treatment schedules (Gr 3) revealed a slightly better performance in spontaneous cycles compared with induced cycles: ovulation rate post-treatment was 97.1%, 94.1% and 94.4% and the pregnancy rate post-treatment was 91.2%, 88.9% and 84.6% for groups 1, 2 and 3, respectively. Nevertheless, fertility in induced and post-treatment oestruses was considered normal. Moreover, the individual litter size did not differ within groups between induced and spontaneous cycles. From these findings, we concluded that treatment with 4.7 mg deslorelin implants did not compromise the bitches' fertility in subsequent oestruses. © 2015 The Authors. Reproduction in Domestic Animals Published by Blackwell Verlag GmbH.

  11. Ministerial Directive No. 1072, June 1985.

    PubMed

    1988-01-01

    This Directive contains nonmandatory guidelines and recommendations for in vitro fertilization and embryo transfer in Chile. The Guidelines are based on the assumption that the constitutional guarantee of the right of the child to be born includes the right to procreate. They set forth the medical reasons for the use of these assisted reproduction techniques, procedures to be followed by institutions applying these techniques, technical facilities, qualifications of medical staff, and the manner in which records are kept. They recommend the mandatory appointment of an Ethics Committee and the obligation to advise couples using these techniques. They also recommend the requirement that all normal and fertilized ovules be returned to the mother and not stored or used for research. full text

  12. Land management on soil physical properties and maize (Zea mays L. var. BIMA) growth (An adaptation strategy of climate change)

    NASA Astrophysics Data System (ADS)

    Zaki, M. K.; Komariah; Pujiasmanto, B.; Noda, K.

    2018-03-01

    Water deficit is a problem on rainfed maize production but can be solved by proper land management. The objective of the study to determine the soil physical properties and maize yield affected by land management to adapt to drought. The experimental design was a randomized complete block using 5 treatments with 4 repetitions, including: (i) Control (KO), (ii) Rice Straw Mulched (MC), (iii) Compost Fertilizer (CF), (iv) In-Organic Fertilizer (AF), (v) Legume Cover crop (CC). Soil physical and maize growth properties namely soil moisture, soil texture, soil bulk density, plant height, biomass, and yield were investigated. The results showed that composting land increased soil water availability and provided nutrient to crops and thus increase soil physical properties, maize growth and yield. Although inorganic fertilizer also increased plant growth and yield, but it did not improve soil physical properties.

  13. Adolescent leadership and adulthood fertility: revisiting the "central theoretical problem of human sociobiology".

    PubMed

    Jokela, Markus; Keltikangas-Järvinen, Liisa

    2009-02-01

    Human motivation for social status may reflect an evolved psychological adaptation that increased individual reproductive success in the evolutionary past. However, the association between status striving and reproduction in contemporary humans is unclear. It may be hypothesized that personality traits related to status achievement increase fertility even if modern indicators of socioeconomic status do not. We examined whether four subcomponents of type-A personality--leadership, hard-driving, eagerness, and aggressiveness--assessed at the age of 12 to 21 years predicted the likelihood of having children by the age of 39 in a population-based sample of Finnish women and men (N=1,313). Survival analyses indicated that high adolescent leadership increased adulthood fertility in men and women, independently of education level and urbanicity of residence. The findings suggest that personality determinants of status achievement may predict increased reproductive success in contemporary humans.

  14. The Death of the West: An alternative view.

    PubMed

    Coleman, David; Basten, Stuart

    2015-01-01

    Much has been written about the 'Death of the West', a demise threatened by the low level of reproduction in Western countries. That fate is contrasted unfavourably with the rapid growth of the populations and economies of less developed countries, and the prospect of the numerical and political marginalization of the formerly dominant developed world. We believe that trends in European fertility have been misunderstood and that, with effort and some pain, their consequences for age structure are manageable. Many European societies also enjoy the advantages of demographic and social maturity, the resilience of established consensual democratic institutions, the rule of law, and civil society. The sizes of China and India raise problems of resource sustainability and vulnerability to climate change. China risks falling into a low-fertility trap, reinforced by urban working conditions unfriendly to family formation. Traditional patriarchal and familist cultures may depress fertility rates to unhelpfully low levels in other less developed countries.

  15. Breast cancer risk after exposure to fertility drugs.

    PubMed

    Lo Russo, Giuseppe; Spinelli, Gian Paolo; Tomao, Silverio; Rossi, Belardino; Frati, Luigi; Panici, Pierluigi Benedetti; Vici, Patrizia; Codacci Pisanelli, Giovanni; Tomao, Federica

    2013-02-01

    In recent years, there has been an increase in the diagnosis of infertility. In industrialized countries, approximately 15% of couples experience this problem today, with a negative impact on quality of life. For this reason, assisted reproductive technologies and other treatments, finalized to overcome infertility, have become very common in clinical practice. For a long time, different ovulation-inducing drugs have been used for ovarian follicle stimulation, either as independent therapies or treatments used during in vitro fertilization cycles. Despite this long-term use, the medical care for infertility gave rise to a lively debate about the potential risk of developing breast cancer that has never been settled. Many studies have been conducted to address this question; but their results have been, and still are, contradictory. The aim of this review is to determine the potential link between the use of fertility drugs and the risk of developing breast cancer in women treated for infertility.

  16. Optimal birth control of age-dependent competitive species

    NASA Astrophysics Data System (ADS)

    He, Ze-Rong

    2005-05-01

    We study optimal birth policies for two age-dependent populations in a competing system, which is controlled by fertilities. New results on problems with free final time and integral phase constraints are presented, and the approximate controllability of system is discussed.

  17. Cultural Considerations in Counseling Couples Who Experience Infertility

    ERIC Educational Resources Information Center

    Burnett, Judith A.

    2009-01-01

    Infertility creates challenges affecting various aspects of couples' intimate lives. Practices regarding reproduction are often shaped by cultural messages. Culturally sensitive treatment methods help counselors provide effective therapy to couples with fertility problems. This article describes cultural influences, challenges, and counseling…

  18. Parturition effects on reproductive health in the gilt and sow.

    PubMed

    Peltoniemi, Oat; Björkman, S; Oliviero, C

    2016-10-01

    In this review, we address significant characteristics of parturition in the pig and their connection to post-partum reproductive health and fertility. We discuss the normal physiology and behaviour around parturition and the effect of the second phase (expulsion of foetuses) on the third phase of parturition (expulsion of foetal membranes). In addition, we intend to cover retained placenta, and the connection to post-partum uterine health and fertility in the contemporary prolific sow. We also explore factors that support successful parturition or can cause potential problems. Successful parturition in the pig includes the possibility to express adequate maternal behaviour, rapid expulsion of the piglets, complete expulsion of the placenta, neonatal activity and colostrum intake. Abnormal incidents during any phase of parturition can cause subsequent problems. Duration of the expulsion phase of foetuses can be used as a simple measure of whether parturition is considered successful. Prolonged parturition can impair health of the sow and piglet and fertility after weaning. New insights, such as adding more fibre to sow diets during pregnancy, and especially during the period prior to farrowing, may prevent constipation, increase water intake of the sow around parturition and increase milk intake and performance of piglets. Maternal characteristics, including maternal behaviour, ease of parturition, colostrum production and piglet quality parameters, may be utilized to improve success rate of reproductive management during farrowing and early lactation. Additionally, we share some of the recent developments in methods, including ultrasonography in evaluation of post-partum uterine health. In conclusion, successful farrowing is of the greatest importance for reproductive health of the sow and survival of the piglets. We suggest connections exist among prolonged farrowing and yield of colostrum, retained placenta, development of PDS, and impaired involution of the uterus and reduced subsequent fertility. © 2016 Blackwell Verlag GmbH.

  19. Psychometric properties and factor structure of the Fertility Problem Inventory in a sample of infertile women undergoing fertility treatment.

    PubMed

    Gourounti, K; Anagnostopoulos, F; Vaslamatzis, G

    2011-10-01

    to examine the psychometric properties of the Fertility Problem Inventory (FPI) originally developed by Newton et al. (1999); as there are no data concerning the factorial structure of the FPI, a special focus is placed on construct validity through factor analysis. public hospital in Athens, Greece. a cross-sectional study. 108 women undergoing fertility treatment with in-vitro fertilisation. the FPI was 'forward-backward' translated from English to Greek. The translated instrument was then administered to a set of infertile women for pilot testing. Principal axis factoring with promax rotation was used to test the factor structure of the FPI. Measures of anxiety State Trait Anxiety Inventory, depression (Center for Epidemiologic Studies--Depression Scale) and mood states Profile of Mood States were used to assess the convergent validity of the FPI. Cronbach's α was used to measure internal consistency of the FPI scales. exploratory factor analysis suggested four factors. The majority of relationship and sexual concern items grouped into one solid factor, named 'spousal concern'. The original scales of social concern, need for parenthood and rejection of childfree lifestyle were reproduced after rearranging nine cross-loading items. Construct validity was confirmed by computing correlations between the derived FPI scales and conceptually similar constructions of anxiety, depression and mood states. Internal consistency reliability was satisfactory. the FPI was found to have a relatively stable factor structure and satisfactory reliability, and convergent and discriminant validity. The FPI may enable researchers and clinicians to apply a reliable measure that focuses on various/many dimensions of infertility-related stress. Copyright © 2010 Elsevier Ltd. All rights reserved.

  20. Lipid Extracted Microalgal Biomass Residue as a Fertilizer Substitute for Zea mays L.

    PubMed Central

    Maurya, Rahulkumar; Chokshi, Kaumeel; Ghosh, Tonmoy; Trivedi, Khanjan; Pancha, Imran; Kubavat, Denish; Mishra, Sandhya; Ghosh, Arup

    2016-01-01

    High volumes of lipid extracted microalgal biomass residues (LMBRs) are expected to be produced upon commencement of biodiesel production on a large scale, thus necessitating its value addition for sustainable development. LMBRs of Chlorella variabilis and Lyngbya majuscula were employed to substitute the nitrogen content of recommended rate of fertilizer (RRF) for Zea mays L. The pot experiment comprised of 10 treatments, i.e., T1 (No fertilizer); T2 (RRF-120 N: 60 P2O5: 40 K2O kg ha−1); T3 to T6—100, 75, 50, and 25% N through LMBR of the Chlorella sp., respectively; T7 to T10—100, 75, 50, and 25% N through LMBR of Lyngbya sp., respectively. It was found that all LMBR substitution treatments were at par to RRF with respect to grain yield production. T10 gave the highest grain yield (65.16 g plant−1), which was closely followed by that (63.48 g plant−1) under T5. T10 also recorded the highest phosphorus and potassium contents in grains. T4 was markedly superior over control in terms of dry matter accumulation (DMA) as well as carbohydrate content, which was ascribed to higher pigment content and photosynthetic activity in leaves. Even though considerably lower DMA was obtained in Lyngbya treatments, which might have been due to the presence of some toxic factors, no reduction in grain yield was apparent. The length of the tassel was significantly higher in either of the LMBRs at any substitution rates over RRF, except T6 and T7. The ascorbate peroxidase activity decreased with decreasing dose of Chlorella LMBR, while all the Lyngbya LMBR treatments recorded lower activity, which were at par with each other. Among the Chlorella treatments, only T5 recorded significantly higher values of glutathione reductase activity over RRF, while the rest were at par. There were significant increases in carbohydrate and crude fat, respectively, only in T4 and T3 over RRF, while no change was observed in crude protein due to LMBR treatments. Apparently, there was no detrimental effect on soil properties, suggesting that both the LMBRs can be employed to reduce the usage of chemical fertilizers, thus promoting maize crop production in a sustainable manner. PMID:26834768

  1. Lipid Extracted Microalgal Biomass Residue as a Fertilizer Substitute for Zea mays L.

    PubMed

    Maurya, Rahulkumar; Chokshi, Kaumeel; Ghosh, Tonmoy; Trivedi, Khanjan; Pancha, Imran; Kubavat, Denish; Mishra, Sandhya; Ghosh, Arup

    2015-01-01

    High volumes of lipid extracted microalgal biomass residues (LMBRs) are expected to be produced upon commencement of biodiesel production on a large scale, thus necessitating its value addition for sustainable development. LMBRs of Chlorella variabilis and Lyngbya majuscula were employed to substitute the nitrogen content of recommended rate of fertilizer (RRF) for Zea mays L. The pot experiment comprised of 10 treatments, i.e., T1 (No fertilizer); T2 (RRF-120 N: 60 P2O5: 40 K2O kg ha(-1)); T3 to T6-100, 75, 50, and 25% N through LMBR of the Chlorella sp., respectively; T7 to T10-100, 75, 50, and 25% N through LMBR of Lyngbya sp., respectively. It was found that all LMBR substitution treatments were at par to RRF with respect to grain yield production. T10 gave the highest grain yield (65.16 g plant(-1)), which was closely followed by that (63.48 g plant(-1)) under T5. T10 also recorded the highest phosphorus and potassium contents in grains. T4 was markedly superior over control in terms of dry matter accumulation (DMA) as well as carbohydrate content, which was ascribed to higher pigment content and photosynthetic activity in leaves. Even though considerably lower DMA was obtained in Lyngbya treatments, which might have been due to the presence of some toxic factors, no reduction in grain yield was apparent. The length of the tassel was significantly higher in either of the LMBRs at any substitution rates over RRF, except T6 and T7. The ascorbate peroxidase activity decreased with decreasing dose of Chlorella LMBR, while all the Lyngbya LMBR treatments recorded lower activity, which were at par with each other. Among the Chlorella treatments, only T5 recorded significantly higher values of glutathione reductase activity over RRF, while the rest were at par. There were significant increases in carbohydrate and crude fat, respectively, only in T4 and T3 over RRF, while no change was observed in crude protein due to LMBR treatments. Apparently, there was no detrimental effect on soil properties, suggesting that both the LMBRs can be employed to reduce the usage of chemical fertilizers, thus promoting maize crop production in a sustainable manner.

  2. Effects of combined application of organic and inorganic fertilizers plus nitrification inhibitor DMPP on nitrogen runoff loss in vegetable soils.

    PubMed

    Yu, Qiaogang; Ma, Junwei; Zou, Ping; Lin, Hui; Sun, Wanchun; Yin, Jianzhen; Fu, Jianrong

    2015-01-01

    The application of nitrogen fertilizers leads to various ecological problems such as large amounts of nitrogen runoff loss causing water body eutrophication. The proposal that nitrification inhibitors could be used as nitrogen runoff loss retardants has been suggested in many countries. In this study, simulated artificial rainfall was used to illustrate the effect of the nitrification inhibitor DMPP (3,4-dimethyl pyrazole phosphate) on nitrogen loss from vegetable fields under combined organic and inorganic nitrogen fertilizer application. The results showed that during the three-time simulated artificial rainfall period, the ammonium nitrogen content in the surface runoff water collected from the DMPP application treatment increased by 1.05, 1.13, and 1.10 times compared to regular organic and inorganic combined fertilization treatment, respectively. In the organic and inorganic combined fertilization with DMPP addition treatment, the nitrate nitrogen content decreased by 38.8, 43.0, and 30.1% in the three simulated artificial rainfall runoff water, respectively. Besides, the nitrite nitrogen content decreased by 95.4, 96.7, and 94.1% in the three-time simulated artificial rainfall runoff water, respectively. A robust decline in the nitrate and nitrite nitrogen surface runoff loss could be observed in the treatments after the DMPP addition. The nitrite nitrogen in DMPP addition treatment exhibited a significant low level, which is near to the no fertilizer application treatment. Compared to only organic and inorganic combined fertilizer treatment, the total inorganic nitrogen runoff loss declined by 22.0 to 45.3% in the organic and inorganic combined fertilizers with DMPP addition treatment. Therefore, DMPP could be used as an effective nitrification inhibitor to control the soil ammonium oxidation in agriculture and decline the nitrogen runoff loss, minimizing the nitrogen transformation risk to the water body and being beneficial for the ecological environment.

  3. [Effect of different N, P and K fertilizers on soil pH and available Cd under waterlogged conditions].

    PubMed

    Jia, Ka-La-Tie; Yu, Hua; Feng, Wen-Qiang; Qin, Yu-Sheng; Zhao, Jing; Liao, Ming-Lan; Wang, Chang-Quan; Tu, Shi-Hua

    2009-11-01

    In order to tackle the problem of Cd pollution in paddy soils and investigate soil available Cd as affected by different fertilizers, incubation experiments were carried out to study the effects of different N, P and K fertilizers and pH by adding acid or base on soil available Cd under waterlogged conditions. Results revealed that soil pH increased sharply after the soil was flooded, especially at the beginning of incubation, and gradually decreased with incubation time and finally tended to approach the neutral values. The patterns of soil pH change were just opposite to those of soil available Cd, a negative correlation observed between the two. Soil flooding made the soil available Cd drop by 58.2%-84.1%. There were significant differences between different fertilizer types/varieties on soil available Cd, being most complex with N fertilizers and followed by K and P fertilizers. Among the fertilizers studied, ammonium chloride showed the unique ability in reducing soil pH and enhancing soil available Cd, and urea, single super phosphate and potassium chloride also promoted to a less extent amounts of Cd extracted from the soil. Ammonium sulfate, potassium sulfate and mono-ammonium phosphate significantly decreased soil available Cd compared to the CK treatment. Whether or not the soil was flooded, soil available Cd was highly negatively correlated with soil pH after adding acid or base (R = - 0.994 without incubation and R = - 0.919 after incubation for 60 d). The results further suggest that in the Cd polluted paddy soil, use of ammonium chloride should be avoided, S bearing fertilizers in combination with alkaline materials can be adopted, and the rice field should be flooded all the time during growing season, all the these practices can effectively lower soil available Cd.

  4. Fertility-related knowledge and reproductive goals in childhood cancer survivors: short communication.

    PubMed

    Lehmann, V; Keim, M C; Nahata, L; Shultz, E L; Klosky, J L; Tuinman, M A; Gerhardt, C A

    2017-11-01

    Do young adult survivors of childhood cancer know their fertility status, in the context of their parenthood goals and screening for gonadal functioning? While 80% of survivors (who were without children) wanted children in the future, most did not know their fertility status, and screening for gonadal functioning was underutilized. Survivors of childhood cancer are at risk for infertility, but fertility counseling and assessment are underutilized. Separate studies indicated that survivors' fertility-related knowledge is poor and that they often wanted to have children. Yet, studies have not investigated the intersection of both issues, as well as potential distress if parenthood goals are not met. Young adult male and female survivors of childhood cancer (N = 149) completed cross-sectional surveys, and data for those without children (n = 105, 70.5%) are presented here. Participants were 20-40 years old (M = 26.5), diagnosed 5-33 years prior to study participation, and completed questionnaires online. Knowledge of fertility status, parenthood goals, and potential distress if survivors were unable to have children were assessed. Medical records were reviewed for hormone levels as indicators of screening for gonadal functioning. Most survivors (n = 81; 77.1%) did not know their fertility status, while over 80% (n = 89) wanted children (neither aspect varied by socio-demographic/cancer-specific factors). Two-thirds of survivors indicated they would be distressed if parenthood goals remained unfulfilled; especially female (versus male, t = 2.64; P = 0.01) or partnered (versus single, t = -3.45; P < 0.001) survivors. Forty survivors (38.1%) had documented assessments of gonadal functioning, of which 33 (82.5%) reported not knowing their fertility status. Relevant risk factors may have not been identified owing to limited sample size and missing treatment information. The underutilization of screening for gonadal functioning needs further exploration in other pediatric centers. Most adult childhood cancer survivors want to become parents, but do not know their fertility status, which could cause significant psychological distress. Healthcare providers should continuously address fertility among survivors, but more research is needed on how to implement routine fertility counseling and/or testing. This study was funded by the Research Institute at Nationwide Children's Hospital (V.L.) and Dutch Cancer Society (RUG2009-4442, M.A.T.). All authors have no conflict of interest to declare. © The Author 2017. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

  5. Effects of environmental factors on edible oil quality of organically grown Camelina sativa.

    PubMed

    Kirkhus, Bente; Lundon, Aina R; Haugen, John-Erik; Vogt, Gjermund; Borge, Grethe Iren A; Henriksen, Britt I F

    2013-04-03

    The aim of the present study was to evaluate the potential for the production of edible oil from organically grown camelina ( Camelina sativa L. Crantz), focusing on the influence of environmental factors on nutritional quality parameters. Field experiments with precrop barley were conducted in Norway in the growing seasons 2007, 2008, and 2009. Trials were fully randomized with two levels of nitrogen (N) fertilization, 0 and 120 kg total N ha(-1), and two levels of sulfur (S) fertilization, 0 and 20 kg total S ha(-1). Weather conditions, that is, temperature and precipitation, were recorded. Additional experiments were performed in the years 2008 and 2009 to evaluate the effects of replacing precrop barley with precrop pea. Seed oil content was measured by near-infrared transmittance, and crude oil compositions of fatty acids, phytosterols, tocopherols, and phospholipids were analyzed by chromatography and mass spectrometry. Results showed significant seasonal variations in seed oil content and oil composition of fatty acids, tocopherols, phytosterols, and phospholipids that to a great extent could be explained by the variations in weather conditions. Furthermore, significant effects of N fertilization were observed. Seed oil content decreased at the highest level of N fertilization, whereas the oil concentrations of α-linolenic acid (18:3n-3), erucic acid (22:1n-9), tocopherols, and campesterol increased. Pea compared to barley as precrop also increased the 18:3n-3 content of oil. S fertilization had little impact on oil composition, but an increase in tocopherols and a decrease in brassicasterol were observed. In conclusion, organically grown camelina seems to be well suited for the production of edible oil. Variations in nutritional quality parameters were generally small, but significantly influenced by season and fertilization.

  6. South Korea's low fertility raises European-style issues.

    PubMed

    Haub, C

    1991-10-01

    A demographic revolution has taken place in South Korea as evidenced by the marked decline in total fertility rate (TFR) from 6 in 1960 to the 1987 level of 1.6. South Korea holds the record for low fertility among developing countries, with women in South Korea averaging fewer children in their lifetimes than do women in Europe. The 1987 TFR for South Korea was even less than that of Sweden, Norway, and France. Emphasizing high initial rates of contraceptive use, family planning (FP) has been a strong component of South Korea's 5-year plans since 1962. Strong governmental support backed the efforts of a large group of FP workers who provided free contraceptives from private physicians. High discontinuation rates resulted, however, and the abortion rate has soared to equal the number of live births. Albeit a developing nation, South Korea now faces the challenges of below replacement fertility more typical of more developed countries. Current fertility levels indicate population increase to approximately 50 million by 2020, followed by a slow decline. While reducing pressure on limited resources, population decline and demographic aging will also demand allocation of a higher proportion of government funds to medical care, and potentially threaten South Korea's competitiveness in the world labor market. Having effected decreases in population growth and fertility, the government reduced the annual sterilization target in 1986 from 300,000 to 60,000 by 1991, and will increasingly turn to the private sector and national health insurance for service provision to all but the poor. A 2-child family norm may be promoted, FP programs expanded to the unmarried and legislation developed to eliminate the preference for sons. Delivery systems may also be reorganized to encourage continued use of contraceptive methods.

  7. Modern fertility awareness methods: Wrist wearables capture the changes of temperature associated with the menstrual cycle.

    PubMed

    Shilaih, Mohaned; Goodale, Brianna M; Falco, Lisa; Kübler, Florian; De Clerck, Valerie; Leeners, Brigitte

    2017-11-24

    Core and peripheral body temperatures are affected by changes in reproductive hormones during the menstrual cycle. Women worldwide use the basal body temperature (BBT) method to aid and prevent conception. However, prior research suggests taking one's daily temperature can prove inconvenient and subject to environmental factors. We investigate whether a more automatic, non-invasive temperature measurement system can detect changes in temperature across the menstrual cycle. We examined how wrist-skin temperature (WST), measured with wearable sensors, correlates with urinary tests of ovulation and may serve as a new method of fertility tracking. One hundred and thirty-six eumenorrheic, non-pregnant women participated in an observational study. Participants wore WST biosensors during sleep and reported their daily activities. An at-home luteinizing hormone test was used to confirm ovulation. WST was recorded across 437 cycles (mean cycles/participant=3.21, S.D.=2.25). We tested the relationship between the fertile window and WST temperature shifts, using the BBT three-over-six rule. A sustained three-day temperature shift was observed in 357/437 cycles (82%), with the lowest cycle temperature occurring in the fertile window 41% of the time. Most temporal shifts (307/357, 86%) occurred on ovulation day or later. The average early-luteal phase temperature was 0.33°C higher than in the fertile window. Menstrual cycle changes in WST were impervious to lifestyle factors, like having sex, alcohol or eating prior to bed, that, in prior work, have been shown to obfuscate BBT readings. Although currently costlier than BBT, this study suggests that WST could be a promising, convenient parameter for future multi-parameter fertility-awareness methods. ©2017 The Author(s).

  8. Bacterial impregnation of mineral fertilizers improves yield and nutrient use efficiency of wheat.

    PubMed

    Ahmad, Shakeel; Imran, Muhammad; Hussain, Sabir; Mahmood, Sajid; Hussain, Azhar; Hasnain, Muhammad

    2017-08-01

    The fertilizer use efficiency (FUE) of agricultural crops is generally low, which results in poor crop yields and low economic benefits to farmers. Among the various approaches used to enhance FUE, impregnation of mineral fertilizers with plant growth-promoting bacteria (PGPB) is attracting worldwide attention. The present study was aimed to improve growth, yield and nutrient use efficiency of wheat by bacterially impregnated mineral fertilizers. Results of the pot study revealed that impregnation of diammonium phosphate (DAP) and urea with PGPB was helpful in enhancing the growth, yield, photosynthetic rate, nitrogen use efficiency (NUE) and phosphorus use efficiency (PUE) of wheat. However, the plants treated with F8 type DAP and urea, prepared by coating a slurry of PGPB (Bacillus sp. strain KAP6) and compost on DAP and urea granules at the rate of 2.0 g 100 g -1 fertilizer, produced better results than other fertilizer treatments. In this treatment, growth parameters including plant height, root length, straw yield and root biomass significantly (P ≤ 0.05) increased from 58.8 to 70.0 cm, 41.2 to 50.0 cm, 19.6 to 24.2 g per pot and 1.8 to 2.2 g per pot, respectively. The same treatment improved grain yield of wheat by 20% compared to unimpregnated DAP and urea (F0). Likewise, the maximum increase in photosynthetic rate, grain NP content, grain NP uptake, NUE and PUE of wheat were also recorded with F8 treatment. The results suggest that the application of bacterially impregnated DAP and urea is highly effective for improving growth, yield and FUE of wheat. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  9. Does a dedicated program for young breast cancer patients affect the likelihood of fertility preservation discussion and referral?

    PubMed

    Srikanthan, Amirrtha; Amir, Eitan; Warner, Ellen

    2016-06-01

    To assess whether a dedicated program for young breast cancer patients, including a nurse navigator, improves the frequency of: a) fertility discussion documentation and b) fertility preservation (FP) referrals. A retrospective chart review and prospective survey were undertaken of breast cancer patients diagnosed at age 40 or younger between 2011 and 2013 who received adjuvant or neo-adjuvant chemotherapy at two academic cancer centers in Toronto, Canada. The Odette Cancer Centre (OCC) has a dedicated program for young breast cancer patients while Princess Margaret Cancer Centre (PM) does not. Patient demographics, tumor pathology, treatment and fertility discussion documentation prior to systemic chemotherapy administration were extracted from patient records. Prospective surveys were administered to the same cohort to corroborate data collected. Eighty-one patient charts were reviewed at both OCC and PM. Forty-seven and 49 at OCC and PM returned surveys for a response rate of 58% and 60% respectively. Chart reviews demonstrated no difference in the frequency of fertility discussion documentation (78% versus 75% for OCC and PM, p = 0.71); however, surveys demonstrated higher rates of recall of fertility discussion at OCC (96% versus 80%, p = 0.02). A greater proportion of women were offered FP referrals at OCC, as observed in chart reviews (56% versus 41%, p = 0.09), and surveys (73% versus 51%, p = 0.04). Time to initiation of chemotherapy did not differ between women who underwent FP and those who did not. A dedicated program for young breast cancer patients is associated with a higher frequency of FP referrals without delaying systemic therapy. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. Is there a trade-off between fertility and longevity? A comparative study of women from three large historical databases accounting for mortality selection.

    PubMed

    Gagnon, Alain; Smith, Ken R; Tremblay, Marc; Vézina, Hélène; Paré, Paul-Philippe; Desjardins, Bertrand

    2009-01-01

    Frontier populations provide exceptional opportunities to test the hypothesis of a trade-off between fertility and longevity. In such populations, mechanisms favoring reproduction usually find fertile ground, and if these mechanisms reduce longevity, demographers should observe higher postreproductive mortality among highly fertile women. We test this hypothesis using complete female reproductive histories from three large demographic databases: the Registre de la population du Québec ancien (Université de Montréal), which covers the first centuries of settlement in Quebec; the BALSAC database (Université du Québec à Chicoutimi), including comprehensive records for the Saguenay-Lac-St-Jean (SLSJ) in Quebec in the nineteenth and twentieth centuries; and the Utah Population Database (University of Utah), including all individuals who experienced a vital event on the Mormon Trail and their descendants. Together, the three samples allow for comparisons over time and space, and represent one of the largest set of natural fertility cohorts used to simultaneously assess reproduction and longevity. Using survival analyses, we found a negative influence of parity and a positive influence of age at last child on postreproductive survival in the three populations, as well as a significant interaction between these two variables. The effect sizes of all these parameters were remarkably similar in the three samples. However, we found little evidence that early fertility affects postreproductive survival. The use of Heckman's procedure assessing the impact of mortality selection during reproductive ages did not appreciably alter these results. We conclude our empirical investigation by discussing the advantages of comparative approaches. 2009 Wiley-Liss, Inc.

  11. Effect of manure under different nitrogen application rates on winter wheat production and soil fertility in dryland

    NASA Astrophysics Data System (ADS)

    Zhang, H. Q.; Yu, X. Y.; Zhai, B. N.; Jin, Z. Y.; Wang, Z. H.

    2016-08-01

    Exploring an effective fertilization practice is crucial for achieving a sustainable dryland winter wheat cropping system. Following a split-plot design, this study was conducted to investigate the combined effect of manure (-M or +M; main plot) and various rates of nitrogen (N) fertilizer (0, 75, 150, 225, and 300 kg N ha-1; sub plot) on grain yield, water and N use efficiencies of winter wheat, and soil nutrients. The results showed that the treatments with manure improved the grain yield by 8%, and WUE by 10% relative to that without manure throughout the study years. The highest winter wheat yield and WUE were both recorded in the M+N225 treatment, which were not significantly different from those for M+N75 and M+N150 treatment. In contrast, high levels of N fertilizer (> 150 kg N ha-1) combined with manure not only caused a reduction in the N use efficiency (NUE), but it also caused an increase in the soil residual nitrate-N (from 43.7 to 188.9 kg ha-1) relative to without manure. After three years of continuous cropping, the treatment combining manure with 150 kg N ha-1 fertilizer had the highest SOM, available P and available K, which was 24%, 379% and 102% higher than that for unfertilized treatment (CK), and 10%, 267%, and 55% higher than that for without manure, respectively. Thus, the combination of manure (17.5 t ha-1 poultry or 30 t ha-1 pig manure) with 75-150 kg N ha-1 N fertilizer is recommended for improving winter wheat yield, water and N use efficiencies, and reducing soil nitrate-N residue as well.

  12. Inferring relationships between clinical mastitis, productivity and fertility: a recursive model application including genetics, farm associated herd management, and cow-specific antibiotic treatments.

    PubMed

    Rehbein, Pia; Brügemann, Kerstin; Yin, Tong; V Borstel, U König; Wu, Xiao-Lin; König, Sven

    2013-10-01

    A dataset of test-day records, fertility traits, and one health trait including 1275 Brown Swiss cows kept in 46 small-scale organic farms was used to infer relationships among these traits based on recursive Gaussian-threshold models. Test-day records included milk yield (MY), protein percentage (PROT-%), fat percentage (FAT-%), somatic cell score (SCS), the ratio of FAT-% to PROT-% (FPR), lactose percentage (LAC-%), and milk urea nitrogen (MUN). Female fertility traits were defined as the interval from calving to first insemination (CTFS) and success of a first insemination (SFI), and the health trait was clinical mastitis (CM). First, a tri-trait model was used which postulated the recursive effect of a test-day observation in the early period of lactation on liability to CM (LCM), and further the recursive effect of LCM on the following test-day observation. For CM and female fertility traits, a bi-trait recursive Gaussian-threshold model was employed to estimate the effects from CM to CTFS and from CM on SFI. The recursive effects from CTFS and SFI onto CM were not relevant, because CM was recorded prior to the measurements for CTFS and SFI. Results show that the posterior heritability for LCM was 0.05, and for all other traits, heritability estimates were in reasonable ranges, each with a small posterior SD. Lowest heritability estimates were obtained for female reproduction traits, i.e. h(2)=0.02 for SFI, and h(2)≈0 for CTFS. Posterior estimates of genetic correlations between LCM and production traits (MY and MUN), and between LCM and somatic cell score (SCS), were large and positive (0.56-0.68). Results confirm the genetic antagonism between MY and LCM, and the suitability of SCS as an indicator trait for CM. Structural equation coefficients describe the impact of one trait on a second trait on the phenotypic pathway. Higher values for FAT-% and FPR were associated with a higher LCM. The rate of change in FAT-% and in FPR in the ongoing lactation with respect to the previous LCM was close to zero. Estimated recursive effects between SCS and CM were positive, implying strong phenotypic impacts between both traits. Structural equation coefficients explained a detrimental impact of CM on female fertility traits CTFS and SFI. The cow-specific CM treatment had no significant impact on performance traits in the ongoing lactation. For most treatments, beta-lactam-antibiotics were used, but test-day SCS and production traits after the beta-lactam-treatment were comparable to those after other antibiotic as well as homeopathic treatments. Copyright © 2013 Elsevier B.V. All rights reserved.

  13. Impact of vegetation control and annual fertilization on properties of loblolly pine wood at age 12

    Treesearch

    Alexander Clark; Bruce E. Borders; Richard F. Daniels

    2004-01-01

    Loblolly pine (Pinus taeda L.) stands in the Coastal Plain and Piedmont of Georgia were subjected to four intensive silvicultural regimes to monitor and record relative tree growth. Treatments included: intensive mechanical site preparation, complete vegetation control with multiple applications of herbicides, annual high rates of nitrogen...

  14. Commercial fertilizers: Total US fertilizer consumption 44.9 million tons in 1989

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hargett, N.L.; Berry, J.T.; McKinney, S.L.

    1989-12-31

    US fertilizer consumption for the 1988--1989 year was 44.9 million tons of material-an increase of less than one percent from the previous year. The average plant nutrient content of all fertilizers decreased slightly as total plant nutrient consumption declined from 19.61 million to 19.59 million tons of N, P{sub 2}O{sub 5}, and K{sub 2}O. Total nitrogen consumption increased one percent to 10.63 million tons, while P{sub 2}O{sub 5} use decreased by less than one percent to 4.12 million tons. Potash consumption declined from 4.97 million tons to 4.83 million tons K{sub 2}O-a 2.8 percent decrease. Consumption patterns varied widely frommore » state to state as weather conditions adversely affected fertilizer application even with significant increases in total planted crop acreage. Illinois, Indiana, Iowa, Minnesota, and Ohio reported a decline in total plant nutrient application while several of the southeastern states registered an increase in consumption. Nutrient levels in mixed fertilizers remained unchanged as slight gains in the nitrogen and P{sub 2}O{sub 5} content were offset by a decline in K{sub 2}O. Consumption of ammonium polyphosphate solution (10-34-0) and monoammonium phosphates increased 9.2 percent and 12.8 percent respectively, while diammonium phosphate (18-46-0) use was 2.4 percent below last year. A general increase in the use of nitrogen materials was reported with the exception of nitrogen solutions which declined 2.1 percent from 1987--1988. Urea consumption rose almost 2 percent. ammonium nitrate was up 8.1 percent, and ammonium sulfate recorded a 9.5 percent gain in consumption. Anhydrous ammonia use was only 35,000 tons above last year. This document contains a state by state listing of individual fertilizer consumption rates, numerical data only.« less

  15. Commercial fertilizers: Total US fertilizer consumption 44. 9 million tons in 1989

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hargett, N.L.; Berry, J.T.; McKinney, S.L.

    1989-01-01

    US fertilizer consumption for the 1988--1989 year was 44.9 million tons of material-an increase of less than one percent from the previous year. The average plant nutrient content of all fertilizers decreased slightly as total plant nutrient consumption declined from 19.61 million to 19.59 million tons of N, P[sub 2]O[sub 5], and K[sub 2]O. Total nitrogen consumption increased one percent to 10.63 million tons, while P[sub 2]O[sub 5] use decreased by less than one percent to 4.12 million tons. Potash consumption declined from 4.97 million tons to 4.83 million tons K[sub 2]O-a 2.8 percent decrease. Consumption patterns varied widely frommore » state to state as weather conditions adversely affected fertilizer application even with significant increases in total planted crop acreage. Illinois, Indiana, Iowa, Minnesota, and Ohio reported a decline in total plant nutrient application while several of the southeastern states registered an increase in consumption. Nutrient levels in mixed fertilizers remained unchanged as slight gains in the nitrogen and P[sub 2]O[sub 5] content were offset by a decline in K[sub 2]O. Consumption of ammonium polyphosphate solution (10-34-0) and monoammonium phosphates increased 9.2 percent and 12.8 percent respectively, while diammonium phosphate (18-46-0) use was 2.4 percent below last year. A general increase in the use of nitrogen materials was reported with the exception of nitrogen solutions which declined 2.1 percent from 1987--1988. Urea consumption rose almost 2 percent. ammonium nitrate was up 8.1 percent, and ammonium sulfate recorded a 9.5 percent gain in consumption. Anhydrous ammonia use was only 35,000 tons above last year. This document contains a state by state listing of individual fertilizer consumption rates, numerical data only.« less

  16. Links between Iron Fertilization and Biological Pump Efficiency in the Bering Sea Over the Last 3.5 Myrs

    NASA Astrophysics Data System (ADS)

    Bartoli, G. L.; Studer, A. S.; Martinez Garcia, A.; Haug, G. H.

    2011-12-01

    The Bering Sea is one of the major sink of atmospheric CO2 today, due to the efficiency of its biological pump, despite a limitation by iron. Here we present records of iron fertilization by aeolian dust deposition (n-alkane concentration) and phytoplankton nutrient consumption (diatom-bound δ15N record) over the last 3.5 Myrs in the southwestern Bering Sea at Site U1341 drilled during IODP Expedition 323. During the Pliocene Epoch, when sea surface temperatures were 3-4°C warmer than today and sea-ice cover was reduced, the biological pump efficiency during glacial and interglacial stages was minimal, similar to Quaternary interglacials. Low iron deposition and weaker surface water stratification resulting in higher nutrient inputs contributed to reduce the biological pump efficiency until 1.5 Ma. After the intensification of glacial conditions in the Bering Sea and the increase in sea-ice cover and iron inputs, the biological pump efficiency progressively increased, reaching values similar to Quaternary glacials after the mid-Pleistocene transition.

  17. Development of IVF Children.

    ERIC Educational Resources Information Center

    van Balen, Frank

    1998-01-01

    Examines physical and psychological development of children conceived through in vitro fertilization (IVF), focusing on questions related to risk of congenital defects or mental retardation and impact on the parent-child relationship. Concludes that no serious problems have arisen concerning the physical and psychological development of IVF…

  18. Nut traits and nutritional composition of hazelnut (Corylus avellana L.) as influenced by zinc fertilization.

    PubMed

    Özenç, Nedim; Özenç, Damla Bender

    2015-07-01

    Zinc is an essential element for plants and its deficiency is a widespread problem throughout the world, causing decreased yields and nutritional quality. In this study the effect of zinc fertilization on some nut traits and the nutritional composition of 'Tombul' hazelnut (Corylus avellana L.) variety cultivated in the Black Sea region of Turkey was investigated and the contribution of this nut to human nutrition determined. Trials were carried out at 'Tombul' hazelnut orchards, and zinc fertilizers were applied at 0, 0.2, 0.4, 0.8 and 1.6 kg Zn ha(-1) in three consecutive years. Significant differences in some nut traits and mineral composition (protein, total oil, ash, kernel percentage, empty and wrinkled nuts, copper, boron, manganese and molybdenum) were observed with zinc fertilizer applications. In terms of daily nutritional element requirements, 100 g of hazelnut provided about 44.74% phosphorus, 13.39% potassium, 19.32% calcium, 37.49% magnesium, 0.19% sodium, 51.63% iron, 25.73% zinc and 14.05% boron of the recommended daily amounts (RDAs), while copper, manganese and molybdenum contents exceeded their RDAs. In order to improve some nut traits and the mineral composition of hazelnut, 0.8 and 1.6 kg Zn ha(-1) fertilizations could be recommended in practice. © 2014 Society of Chemical Industry.

  19. Field studies on two rock phosphate solubilizing actinomycete isolates as biofertilizer sources

    NASA Astrophysics Data System (ADS)

    Mba, Caroline C.

    1994-03-01

    Recently biotechnology is focusing attention on utilization of biological resources to solve a number of environmental problems such as soil fertility management. Results of microbial studies on earthworm compost in the University of Nigeria farm identified a number of rock phosphate solubilizing actinomycetes. Two of these, isclates 02 and 13, were found to be efficient rock phosphate (RP) solubilizers and fast-growing cellulolytic microbes producing extracellular hydrolase enzymes. In this preliminary field study the two microbial isolates were investigated with respect to their effects on the growth of soybean and egusi as well as their effect on the incidence of toxicity of poultry droppings. Application of these isolates in poultry manure-treated field plots, as microbial fertilizers, brought about yield increases of 43% and 17% with soybeans and 19% and 33% with egusi, respectively. Soil properties were also improved. With isolates 02 and 13, the soil available phosphorus increased at the five-leaf stage, while N-fixation in the soil increased by 45% or 11% relative to control. It was further observed that air-dried poultry manure after four days of incubation was still toxic to soybean. The toxic effect of the applied poultry manure was reduced or eliminated with microbial fertilizers 02 or 13, respectively. The beneficial effects of the microbial organic fertilizer are discussed. Justification for more intensive research on rock phosphate organic fertilizer is highlighted.

  20. When Do States Respond to Low Fertility? Contexts of State Concern in Wealthier Countries, 1976-2011.

    PubMed

    Marshall, Emily A

    2015-06-01

    Since the 1970s, expressions of state concern over low fertility have greatly increased among wealthier countries. This study asks to what extent this increase is explained by demographic factors, national-level economic and political factors, and processes of international diffusion and changing international norms. Analyses integrate the world polity literature on global policy diffusion with a social problems approach to examine international diffusion of state concern among more powerful members of the world polity, a process that can produce changes in international policy consensus. Comparisons of the characteristics of states that do and do not express concern over low fertility find that among wealthier "first-world" countries, state concern has become more responsive to fertility rates: fertility rates are not significantly associated with concern early in the study period, but are strongly associated with concern later in the study period. There is no evidence that integration into the world polity is associated with concern in these countries, and some evidence that less integrated countries are more likely to express concern, suggesting that processes shaping the diffusion of state concern may differ from those identified as shaping policy diffusion in the existing literature. Among "second-world" former Eastern bloc countries, different patterns of associations reflect different political histories: concern is associated only with demographic factors, with no significant change in this association over time.

  1. When Do States Respond to Low Fertility? Contexts of State Concern in Wealthier Countries, 1976–2011

    PubMed Central

    Marshall, Emily A.

    2015-01-01

    Since the 1970s, expressions of state concern over low fertility have greatly increased among wealthier countries. This study asks to what extent this increase is explained by demographic factors, national-level economic and political factors, and processes of international diffusion and changing international norms. Analyses integrate the world polity literature on global policy diffusion with a social problems approach to examine international diffusion of state concern among more powerful members of the world polity, a process that can produce changes in international policy consensus. Comparisons of the characteristics of states that do and do not express concern over low fertility find that among wealthier “first-world” countries, state concern has become more responsive to fertility rates: fertility rates are not significantly associated with concern early in the study period, but are strongly associated with concern later in the study period. There is no evidence that integration into the world polity is associated with concern in these countries, and some evidence that less integrated countries are more likely to express concern, suggesting that processes shaping the diffusion of state concern may differ from those identified as shaping policy diffusion in the existing literature. Among “second-world” former Eastern bloc countries, different patterns of associations reflect different political histories: concern is associated only with demographic factors, with no significant change in this association over time. PMID:26213421

  2. Organ-preserving and reconstructive microsurgery of the fallopian tubes in tubal infertility: still an alternative to in vitro fertilization (IVF).

    PubMed

    Schippert, Cordula; Hille, Ursula; Bassler, Christina; Soergel, Philipp; Hollwitz, Bettina; Garcia-Rocha, Guillermo José

    2010-07-01

    Tubal infertility mostly results from infections. Conception only is possible through complex treatments (in vitro fertilization or surgery). Success cannot be guaranteed, even after repeated treatments. Unfortunately, many couples are not informed about the prospect for success of tubal reconstruction. Problems of in vitro fertilization are low pregnancy and birth rates of 28.4% and <20% respectively (Germany) and the high number of multiple pregnancies (21%). In this retrospective study 462 women with acquired tubal infertility and further 127 women after previous sterilization underwent microsurgical treatment (microsurgical adhesiolysis, anastomosis, fimbrioplasty, salpingostomy, and refertilization due to former sterilization). The main outcome measures are the pregnancy and birth rates following the microsurgical procedure. Pregnancy and birth rates of 43.4% and 29.2%, respectively, were higher than the outcomes post-single in vitro fertilization (abortion: 6.4%, extrauterine pregnancy: 7.9%). When reversal of sterilization was performed, pregnancy and birth rates were higher at 73% and 50.6%, respectively (abortion: 15.7%, extrauterine pregnancy: 6.7%). The advantages of reconstructive microsurgery over in vitro fertilization include the ideally permanent restoration of woman's ability to conceive naturally (repeated pregnancies are possible without further therapy), a high postoperative birth rate overall, and avoidance of multiple births. It is advisable to inform the patient about the objective possibility of reconstructive tubal surgery. Thieme Medical Publishers.

  3. Fertility patients' views about frozen embryo disposition: Results of a multi-institutional U.S. survey

    PubMed Central

    Lyerly, Anne Drapkin; Steinhauser, Karen; Voils, Corrine; Namey, Emily; Alexander, Carolyn; Bankowski, Brandon; Cook-Deegan, Robert; Dodson, William C.; Gates, Elena; Jungheim, Emily S.; McGovern, Peter G.; Myers, Evan R.; Osborn, Barbara; Schlaff, William; Sugarman, Jeremy; Tulsky, James A.; Walmer, David; Faden, Ruth R.; Wallach, Edward

    2010-01-01

    Objective To describe fertility patients' preferences for disposition of cryopreserved embryos and determine factors important to these preferences Design Cross-sectional survey conducted between June 2006 and July 2007 Setting Nine geographically diverse U.S. fertility clinics Participants 1020 fertility patients with cryopreserved embryos Interventions Self-administered questionnaire Main Outcome Measures Likelihood of selecting each of five conventional embryo disposition options: store for reproduction, thaw and discard, donate to another couple, freeze indefinitely, and donate for research; likelihood of selecting each of two alternative options identified in previous research: placement of embryos in the woman's body at an infertile time, and a disposal ceremony; importance of each of 26 considerations to disposition decisions; and views on the embryo's moral status. Results 54% of respondents with cryopreserved embryos were very likely to use them for reproduction, 21% were very likely to donate for research, 7% or fewer were very likely to choose any other option. Respondents who ascribed high importance to concerns about the health or well-being of the embryo, fetus, or future child were more likely to thaw and discard embryos or freeze them indefinitely. Conclusions Fertility patients frequently prefer disposition options not available to them or find available options unacceptable. Restructuring and standardizing the informed consent process and ensuring availability of all disposition options may benefit patients, facilitate disposition decisions and address problems of long term storage. PMID:19061998

  4. Production of bio-fertilizer from microwave vacuum pyrolysis of waste palm shell for cultivation of oyster mushroom (Pleurotus ostreatus)

    NASA Astrophysics Data System (ADS)

    Lun Nam, Wai; Huan Su, Man; Phang, Xue Yee; Chong, Min Yee; Keey Liew, Rock; Ma, Nyuk Ling; Lam, Su Shiung

    2017-11-01

    Microwave vacuum pyrolysis of waste palm shell (WPS) was performed to produce biochar, which was then tested as bio-fertilizer in growing Oyster mushroom (Pleurotus ostreatus). The pyrolysis approach generated a biochar containing a highly porous structure with a high BET surface area (up to 1250 m2/g) and a low moisture content (≤ 10 wt%), exhibiting desirable adsorption properties to be used as bio-fertilizer since it can act as a housing that provides many sites on which living microorganisms (mycelium or plant-growth promoting bacteria) and organic nutrients can be attached or adsorbed onto. This could in turn stimulate plant growth by increasing the availability and supply of nutrients to the targeted host plant. The results from growing Oyster mushroom using the biochar record an impressive growth rate and a monthly production of up to about 550 g of mushroom. The shorter time for mycelium growth on whole baglog (30 days) and the highest yield of Oyster mushroom (550 g) was obtained from the cultivation medium added with 20 g of biochar. Our results demonstrate that the biochar-based bio-fertilizer produce from microwave vacuum pyrolysis of WPS show exceptional promise as an alternative growing substrate for mushroom cultivation.

  5. Production of bio-fertilizer from microwave vacuum pyrolysis of palm kernel shell for cultivation of Oyster mushroom (Pleurotus ostreatus).

    PubMed

    Nam, Wai Lun; Phang, Xue Yee; Su, Man Huan; Liew, Rock Keey; Ma, Nyuk Ling; Rosli, Mohd Haqqi Nazilli Bin; Lam, Su Shiung

    2018-05-15

    Microwave vacuum pyrolysis of palm kernel shell (PKS) was performed to produce biochar, which was then tested as bio-fertilizer in growing Oyster mushroom (Pleurotus ostreatus). The pyrolysis approach produced biochar containing a highly porous structure with a high BET surface area of up to 270m 2 /g and low moisture content (≤10wt%), exhibiting desirable adsorption properties to be used as bio-fertilizer since it can act as a housing that provides many sites on which living microorganisms (mycelium or plant-growth promoting bacteria) and organic nutrients can be attached or adsorbed onto. This could in turn stimulate plant growth by increasing the availability and supply of nutrients to the targeted host plant. The results from growing Oyster mushroom using the biochar recorded an impressive growth rate and a monthly production of up to about 550g of mushroom. A shorter time for mycelium growth on one whole baglog (21days) and the highest yield of Oyster mushroom (550g) were obtained from cultivation medium added with 20g of biochar. Our results demonstrate that the biochar-based bio-fertilizer produced from microwave vacuum pyrolysis of PKS shows exceptional promise as growth promoting material for mushroom cultivation. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Comparison of two fertility-sparing approaches for bilateral borderline ovarian tumours: a randomized controlled study.

    PubMed

    Palomba, S; Zupi, E; Russo, T; Falbo, A; Del Negro, S; Manguso, F; Marconi, D; Tolino, A; Zullo, F

    2007-02-01

    During the childbearing years, the standard fertility-sparing treatment for bilateral borderline ovarian tumours (BOTs) is the unilateral oophorectomy plus controlateral cystectomy. The aim of the present study was to compare the effects of two laparoscopic fertility-sparing surgical procedures for the treatment of bilateral BOTs on recurrence and fertility in young women who desire to conceive as soon as possible. Thirty-two women affected by bilateral early-stage BOTs who desired to conceive were randomized to receive bilateral cystectomy (experimental group, n=15) or oophorectomy plus controlateral cystectomy (control group, n=17). At the first recurrence after childbearing completion, each patient was treated with non-conservative standard treatment. Recurrences and reproductive events were recorded. After a follow-up period of 81 months (19 inter-quartile; 60-96 range), the cumulative pregnancy rate (CPR) (14/15 versus 9/17; P=0.003) and the cumulative probability of first pregnancy (P= 0.011) were significantly higher in the experimental than in control group. No significant (P=0.358) difference between groups was detected in cumulative probability of first recurrence. The laparoscopic bilateral cystectomy followed by non-conservative treatment performed at the first recurrence after the childbearing completion is an effective surgical strategy for patients with bilateral early-stage BOTs who desire to conceive as soon as possible.

  7. Fertility preservation for non-medical reasons: controversial, but increasingly common.

    PubMed

    von Wolff, Michael; Germeyer, Ariane; Nawroth, Frank

    2015-01-16

    Fertility-preserving measures for women are increasingly being performed for non-medical reasons in Germany. This is now a controversial matter. The authors searched the PubMed database for pertinent publications on the basis of their clinical and scientific experience and evaluated relevant data from the registry of the German FertiPROTEKT network (www.fertiprotekt. com). The various fertility-preserving measures that are available are described and critically discussed. In most cases, the creation of a fertility reserve currently involves the cryopreservation of unfertilized oocytes, rather than of ovarian tissue. Most of the women who decide to undergo this procedure are over 35 years old. According to data from the FertiPROTEKT registry, most such procedures carried out in the years 2012 and 2013 involved a single stimulation cycle. The theoretical probability of childbirth per stimulation is 40% in women under age 35 and 30% in women aged 35 to 39. If the oocytes are kept for use at a later date, rather than at once, the maternal risk is higher, because the mother is older during pregnancy. The risk to the child may be higher as well because of the need for in vitro fertilization (IVF). Pregnancy over age 40 often leads to complications such as gestational diabetes and pre-eclampsia. IVF may be associated with a higher risk of epigenetic abnormalities. Ethicists have upheld women's reproductive freedom while pointing out that so-called social freezing merely postpones social problems, rather than solving them. Fertility preservation for non-medical reasons should be critically discussed, and decisions should be made on a case-by-case basis.

  8. In Situ Nitrogen Mineralization, Nitrification, and Ammonia Volatilization in Maize Field Fertilized with Urea in Huanghuaihai Region of Northern China

    PubMed Central

    Zhang, Xuelin; Wang, Qun; Xu, Jun; Gilliam, Frank S.; Tremblay, Nicolas; Li, Chaohai

    2015-01-01

    Nitrogen (N) fertilization potentially affects soil N mineralization and leaching, and can enhance NH3 volatilization, thus impacting crop production. A fertilizer experiment with five levels of N addition (0, 79, 147, 215 and 375 kg N ha-1) was performed in 2009 and 2010 in a maize field in Huanghuaihai region, China, where > 300 kg N ha-1 has been routinely applied to soil during maize growth period of 120 days. Responses of net N mineralization, inorganic N flux (0–10cm), NH3 volatilization, and maize yield to N fertilization were measured. During the growth period, net N mineralization and nitrification varied seasonally, with higher rates occurring in August and coinciding with the R1 stage of maize growth. Soil NO3 −-N contributed to more than 60% of inorganic N flux during maize growth. Cumulative NH3 volatilization increased with N additions, with total NH3 volatilization during maize growth accounting for about 4% of added N. Relative to the control, mean maize yield in the fertilizer treatments increased by 17% and 20% in 2009 and 2010, respectively. However, grain yield, aboveground biomass, and plant N accumulation did not increase with added N at levels > 215 kg N ha-1. These results suggest that the current N rate of 300 kg N ha-1 is not only excessive, but also reduces fertilizer efficacy and may contribute to environmental problems such as global warming and eutrophication of ground water and streams. PMID:25635864

  9. Who’s your mama? Riverine hybridisation of threatened freshwater Trout Cod and Murray Cod

    PubMed Central

    Unmack, Peter J.; Dyer, Fiona J.; Lintermans, Mark

    2016-01-01

    Rates of hybridization and introgression are increasing dramatically worldwide because of translocations, restocking of organisms and habitat modifications; thus, determining whether hybridization is occuring after reintroducing extirpated congeneric species is commensurately important for conservation. Restocking programs are sometimes criticized because of the genetic consequences of hatchery-bred fish breeding with wild populations. These concerns are important to conservation restocking programs, including those from the Australian freshwater fish family, Percichthyidae. Two of the better known Australian Percichthyidae are the Murray Cod, Maccullochella peelii and Trout Cod, Maccullochella macquariensis which were formerly widespread over the Murray Darling Basin. In much of the Murrumbidgee River, Trout Cod and Murray Cod were sympatric until the late 1970s when Trout Cod were extirpated. Here we use genetic single nucleotide polymorphism (SNP) data together with mitochondrial sequences to examine hybridization and introgression between Murray Cod and Trout Cod in the upper Murrumbidgee River and consider implications for restocking programs. We have confirmed restocked riverine Trout Cod reproducing, but only as inter-specific matings, in the wild. We detected hybrid Trout Cod–Murray Cod in the Upper Murrumbidgee, recording the first hybrid larvae in the wild. Although hybrid larvae, juveniles and adults have been recorded in hatcheries and impoundments, and hybrid adults have been recorded in rivers previously, this is the first time fertile F1 have been recorded in a wild riverine population. The F1 backcrosses with Murray cod have also been found to be fertile. All backcrosses noted were with pure Murray Cod. Such introgression has not been recorded previously in these two species, and the imbalance in hybridization direction may have important implications for restocking programs. PMID:27812407

  10. Predicting Nitrogen in Streams: A Comparison of Two Estimates of Fertilizer Application

    NASA Astrophysics Data System (ADS)

    Mehaffey, M.; Neale, A.

    2011-12-01

    Decision makers frequently rely on water and air quality models to develop nutrient management strategies. Obviously, the results of these models (e.g., SWAT, SPARROW, CMAQ) are only as good as the nutrient source input data and recently the Nutrient Innovations Task Group has called for a better accounting of nonpoint nutrient sources. Currently, modelers frequently rely on county level fertilizer sales records combined with acreage of crops to estimate nitrogen sources from fertilizer for counties or watersheds. However, since fertilizer sales data are based on reported amounts they do not necessarily reflect actual use on the fields. In addition the reported sales data quality varies by state resulting in differing accuracy between states. In this study we examine an alternative method potentially providing a more uniform, spatially explicit, estimate of fertilizer use. Our nitrogen application data is estimated at a 30m pixel resolution which allows for scalable inputs for use in water and air quality models. To develop this dataset we combined raster data from the National Cropland data layer (CDL) data with the National Land Cover Data (NLCD). This process expanded the NLCD's 'cultivated crops' classes to included major grains, cover crops, and vegetable and fruits. The Agriculture Resource Management Survey chemical fertilizer application rate data were summarized by crop type and year for each state, encompassing the corn, soybean, spring wheat, and winter wheat crop types (ARMS, 2002-2005). The chemical fertilizer application rate data were then used to estimate annual application parameters for nitrogen, phosphate, potash, herbicide, pesticide, and total pesticide, all expressed on a mass-per-unit-crop-area basis for each state for each crop type. By linking crop types to nitrogen application rates, we can better estimate where applied fertilizer would likely be in excess of the amounts used by crops or where conservation practices may improve retention and uptake helping offset the impacts to water. To test the accuracy of our finer resolution nitrogen application data, we compare its ability to predict nitrogen concentrations in streams with the ability of the county sales data to do the same.

  11. Reducing Soil CO2 Emission and Improving Upland Rice Yield with no-Tillage, Straw Mulch and Nitrogen Fertilization in Northern Benin

    NASA Astrophysics Data System (ADS)

    Dossou-Yovo, E.; Brueggemann, N.; Naab, J.; Huat, J.; Ampofo, E.; Ago, E.; Agbossou, E.

    2015-12-01

    To explore effective ways to decrease soil CO2 emission and increase grain yield, field experiments were conducted on two upland rice soils (Lixisols and Gleyic Luvisols) in northern Benin in West Africa. The treatments were two tillage systems (no-tillage, and manual tillage), two rice straw managements (no rice straw, and rice straw mulch at 3 Mg ha-1) and three nitrogen fertilizers levels (no nitrogen, recommended level of nitrogen: 60 kg ha-1, and high level of nitrogen: 120 kg ha-1). Potassium and phosphorus fertilizers were applied to be non-limiting at 40 kg K2O ha-1 and 40 kg P2O5 ha-1. Four replications of the twelve treatment combinations were arranged in a randomized complete block design. Soil CO2 emission, soil moisture and soil temperature were measured at 5 cm depth in 6 to 10 days intervals during the rainy season and every two weeks during the dry season. Soil moisture was the main factor explaining the seasonal variability of soil CO2 emission. Much larger soil CO2 emissions were found in rainy than dry season. No-tillage planting significantly reduced soil CO2 emissions compared with manual tillage. Higher soil CO2 emissions were recorded in the mulched treatments. Soil CO2 emissions were higher in fertilized treatments compared with non fertilized treatments. Rice biomass and yield were not significantly different as a function of tillage systems. On the contrary, rice biomass and yield significantly increased with application of rice straw mulch and nitrogen fertilizer. The highest response of rice yield to nitrogen fertilizer addition was obtained for 60 kg N ha-1 in combination with 3 Mg ha-1 of rice straw for the two tillage systems. Soil CO2 emission per unit grain yield was lower under no-tillage, rice straw mulch and nitrogen fertilizer treatments. No-tillage combined with rice straw mulch and 60 kg N ha-1 could be used by smallholder farmers to achieve higher grain yield and lower soil CO2 emission in upland rice fields in northern Benin.

  12. Genetic parameters for female fertility, locomotion, body condition score, and linear type traits in Czech Holstein cattle.

    PubMed

    Zink, V; Štípková, M; Lassen, J

    2011-10-01

    The aim of this study was to estimate genetic parameters for fertility traits and linear type traits in the Czech Holstein dairy cattle population. Phenotypic data regarding 12 linear type traits, measured in first lactation, and 3 fertility traits, measured in each of first and second lactation, were collected from 2005 to 2009 in the progeny testing program of the Czech-Moravian Breeders Corporation. The number of animals for each linear type trait was 59,467, except for locomotion, where 53,436 animals were recorded. The 3-generation pedigree file included 164,125 animals. (Co)variance components were estimated using AI-REML in a series of bivariate analyses, which were implemented via the DMU package. Fertility traits included days from calving to first service (CF1), days open (DO1), and days from first to last service (FL1) in first lactation, and days from calving to first service (CF2), days open (DO2), and days from first to last service (FL2) in second lactation. The number of animals with fertility data varied between traits and ranged from 18,915 to 58,686. All heritability estimates for reproduction traits were low, ranging from 0.02 to 0.04. Heritability estimates for linear type traits ranged from 0.03 for locomotion to 0.39 for stature. Estimated genetic correlations between fertility traits and linear type traits were generally neutral or positive, whereas genetic correlations between body condition score and CF1, DO1, FL1, CF2 and DO2 were mostly negative, with the greatest correlation between BCS and CF2 (-0.51). Genetic correlations with locomotion were greatest for CF1 and CF2 (-0.34 for both). Results of this study show that cows that are genetically extreme for angularity, stature, and body depth tend to perform poorly for fertility traits. At the same time, cows that are genetically predisposed for low body condition score or high locomotion score are generally inferior in fertility. Copyright © 2011 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  13. Male fertility and obesity: are ghrelin, leptin and glucagon-like peptide-1 pharmacologically relevant?

    PubMed

    Alves, Marco G; Jesus, Tito T; Sousa, Mário; Goldberg, Erwin; Silva, Branca M; Oliveira, Pedro F

    2016-01-01

    Obesity is rising to unprecedented numbers, affecting a growing number of children, adolescents and young adult men. These individuals face innumerous health problems, including subfertility or even infertility. Overweight and obese men present severe alterations in their body composition and hormonal profile, particularly in ghrelin, leptin and glucagon-like peptide-1 (GLP-1) levels. It is well known that male reproductive health is under the control of the individual's nutritional status and also of a tight network of regulatory signals, particularly hormonal signaling. However, few studies have been focused on the effects of ghrelin, leptin and GLP-1 in male reproduction and how energy homeostasis and male reproductive function are linked. These hormones regulate body glucose homeostasis and several studies suggest that they can serve as targets for anti-obesity drugs. In recent years, our understanding of the mechanisms of action of these hormones has grown significantly. Curiously, their effect on male reproductive potential, that is highly dependent of the metabolic cooperation established between testicular cells, remains a matter of debate. Herein, we review general concepts of male fertility and obesity, with a special focus on the effects of ghrelin, leptin and GLP-1 on male reproductive health. We also discuss the possible pharmacological relevance of these hormones to counteract the fertility problems that overweight and obese men face.

  14. Family Planning Practice by Patterns of Marriage in the North of Iran.

    PubMed

    Taghizadeh, Ziba; Vedadhir, Abouali; Bayani, Fatemeh; Behmanesh, Fereshteh; Ebadi, Abbas; Pourreza, Abolghasem; Abbasi-Shavazi, Mohammad Jalal; Bijani, Ali

    2017-01-01

    The fertility experience in Iran suggests that the family planning programs had an effective role in the fertility reduction. This study aimed to specify patterns of marriage in Iran and especially in a northern city of Iran and to investigate the association between patterns of marriage and contraceptive use before first pregnancy and current contraceptive use. In this cross-sectional study, following the implementation of an expert panel in order to investigate marriage patterns, 880 women aged 15-49 yr old, were selected by multistage cluster sampling and completed the "reproductive practices" questionnaire in Babol City, northern Iran, in 2013. The data were analyzed using IBM SPSS ver.16 and descriptive and analytical parameters. There are three patterns of marriage in the northern part of Iran: Traditional, Mixed and Modern marriage and between different patterns there is no statistically significant difference in the contraceptive use. According to the lack of significant relationship between patterns of marriage and the contraceptives use, which is one of the proximate determinants of fertility, the policy makers should pay attention to other determinants of fertility in order to manage the problems and implications of population decline in the country.

  15. The comparison of family function based on the McMaster model in fertile and infertile women

    PubMed Central

    Zanganeh, B; Kaboudi, M; Ashtarian, H; Kaboudi, B

    2015-01-01

    Introduction: One of the main parts of the lives of infertile impaired is social relationships and their family functions. This study aimed to compare the family function based on the McMaster model in fertile and infertile women. Materials and Methods: This research is a similar one. The population consisted of all infertile women referred to the two infertility centers and fertile females related to health areas located in the same area in Tehran. The sampling method was the convenience one and in both groups, 50 women were recruited as samples and they responded to the demographic and Family Assessment Device (FAD) questionnaires. The obtained information was investigated by using inferential and descriptive statistics and SPSS 22 software. Findings: The results showed the following behavioral control variables (p = 0/ 003), roles (p = 0/ 002), emotional responsiveness (p = 0/ 020) and emotional involvement (p = 0/ 006). There was a clear distinction between fertile and infertile women and infertile women obtained worse scores. Conclusion: The results indicated that infertile women have crucial problems in family functioning that can have an impact on other aspects of life and their health. PMID:28316731

  16. The determination of fertilizer quality of the formed struvite from effluent of a sewage sludge anaerobic digester.

    PubMed

    Uysal, Ayla; Yilmazel, Y Dilsad; Demirer, Goksel N

    2010-09-15

    The formation of struvite (MgNH(4)PO(4).6H(2)O) in wastewater treatment plants can lead to scaling and thus operational problems reducing the treatment efficiency. However, struvite has significant commercial value as an agricultural fertilizer. Therefore, controlled struvite formation in wastewater treatment plants not only presents an opportunity to recover nutrients but also corresponds to the valorization of wastes. NH(4)-N and PO(4)-P removal and recovery from the effluent of a full-scale sewage sludge anaerobic digester via controlled struvite precipitation were investigated in this study. The effect of the residual heavy metal and micropollutant content of the formed struvite on fertilizer quality was also evaluated. Removal efficiencies of NH(4)-N, PO(4)-P and COD were 89.35%, 95% and 39.78% when Mg:N:P molar ratio was 1.5:1:1 and pH was 9.0. Mercury, nickel, zinc and chrome concentrations derived from struvite precipitation were below the regulatory limit for fertilizer usage in Turkey. The precipitate did not contain polychlorinated biphenyls (PCB). X-ray diffraction (XRD) analysis conducted on the precipitate indicated a struvite formation. Copyright 2010 Elsevier B.V. All rights reserved.

  17. Protective Effects of Flax Seed (Linum Usitatissimum) Hydroalcoholic Extract on Fetus Brain in Aged and Young Mice.

    PubMed

    Kamali, Mahsa; Bahmanpour, Soghra

    2016-05-01

    One of the major problems of the aged women or older than 35 is getting pregnant in the late fertility life. Fertility rates begin to decline gradually at the age of 30, more so at 35, and markedly at 40. Even with fertility treatments such as in vitro fertilization, women have more difficulty in getting pregnant or may deliver abnormal fetus. The purpose of this study was to assess the effects of flax seed hydroalcoholic extract on the fetal brain of aged mice and its comparison with young mice. In this experimental study, 32 aged and 32 young mice were divided into 4 groups. Controls received no special treatment. The experimental mice groups, 3 weeks before mating, were fed with flax seed hydroalcoholic extract by oral gavages. After giving birth, the brains of the fetus were removed. Data analysis was performed by statistical test ANOVA using SPSS version 18 (P<0.05). The mean fetus brain weight of aged mother groups compared to the control group was increased significantly (P<0.05). This study showed that flax seed hydroalcoholic extract could improve fetal brain weights in the aged groups.

  18. The low fertility of repeat-breeder cows during summer heat stress is related to a low oocyte competence to develop into blastocysts.

    PubMed

    Ferreira, R M; Ayres, H; Chiaratti, M R; Ferraz, M L; Araújo, A B; Rodrigues, C A; Watanabe, Y F; Vireque, A A; Joaquim, D C; Smith, L C; Meirelles, F V; Baruselli, P S

    2011-05-01

    It was hypothesized the lower fertility of repeat-breeder (RB) Holstein cows is associated with oocyte quality and this negative effect is enhanced during summer heat stress (HS). During the summer and the winter, heifers (H; n=36 and 34, respectively), peak-lactation (PL; n=37 and 32, respectively), and RB (n=36 and 31, respectively) Holstein cows were subjected to ovum retrieval to assess oocyte recovery, in vitro embryonic developmental rates, and blastocyst quality [terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL)-positive cells and total cell number]. The environmental temperature and humidity, respiration rate, and cutaneous and rectal temperatures were recorded in both seasons. The summer HS increased the respiration rate and the rectal temperature of PL and RB cows, and increased the cutaneous temperature and lowered the in vitro embryo production of Holstein cows and heifers. Although cleavage rate was similar among groups [H=51.7% ± 4.5 (n=375), PL=37.9% ± 5.1 (n=390), RB=41.9% ± 4.5 (n=666)], blastocyst rate was compromised by HS, especially in RB cows [H=30.3% ± 4.8 (n=244) vs. 23.3% ± 6.4 (n=150), PL=22.0% ± 4.7 (n=191) vs. 14.6% ± 7.6 (n=103), RB=22.5% ± 5.4 (n=413) vs. 7.9% ± 4.3 (n=177)]. Moreover, the fragmentation rate of RB blastocysts was enhanced during the summer, compared with winter [4.9% ± 0.7 (n=14) vs. 2.2% ± 0.2 (n=78)] and other groups [H=2.5% ± 0.7 (n=13), and PL=2.7% ± 0.6 (n=14)] suggesting that the association of RB fertility problems and summer HS may potentially impair oocyte quality. Our findings provide evidence of a greater sensitivity of RB oocytes to summer HS. Copyright © 2011 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  19. The effect of dual-hemisphere breeding on stallion fertility.

    PubMed

    Walbornn, S R; Love, C C; Blanchard, T L; Brinsko, S P; Varner, D D

    2017-05-01

    Breeding records were analyzed from 24 Thoroughbred stallions that were subjected to dual-hemisphere breeding (DH), including novice (first-year; NOV; n = 11) and experienced (EXP; n = 13) stallions. Fertility variables included seasonal pregnancy rate, pregnancy rate per cycle, and first-cycle pregnancy rate. In addition, values for book size, total number of covers, distribution of mare type (maiden, foaling, and barren) within a stallion's book, cycles per mare, and mare age were examined. Some data were also categorized by mare type (maiden-M, foaling-F, and barren-B). Five separate analyses of the data were performed. For Analyses 1-3, the effects of hemisphere (northern hemisphere [NH] vs. southern hemisphere [SH]) and breeding order (refers to the first [O1] or second [O2] season within the first year of dual-hemisphere breeding) were examined for all stallions (combined group [CG]), NOV stallions only, and EXP stallions only, respectively. Fertility values were generally higher in the SH than the NH (P < 0.05), whereas book size, total number of covers, and cycles per mare were higher in the NH than the SH (P < 0.05). Book size and total covers were negatively correlated to first cycle pregnancy rate (r = -0.57, r = -0.71, respectively; P < 0.05) for NOV stallions. Pregnancy rate per cycle was also negatively correlated with total covers (r = -0.58; P < 0.05) for NOV stallions. Similar trends were noted for Groups CG and EXP, but the relationship was not as marked as for NOV stallions. The fertility of O1 was generally similar to O2 (P > 0.05). For Analysis 4, fertility of DH breeding seasons was compared to single hemisphere (SIN) breeding seasons within the same 16 stallions and was found to be similar between the two groups (P > 0.05). For Analysis 5, the effect of the number of consecutive DH breeding seasons on fertility was examined and was found to remain unchanged (P > 0.05). In summary, no adverse effects of DH breeding on fertility were detected. Fertility was higher when stallions were bred in the SH, as compared to the NH. Potential reasons for higher fertility achieved in the SH were smaller book sizes and better mare reproductive quality. Copyright © 2017. Published by Elsevier Inc.

  20. Teaching Science with Soil.

    ERIC Educational Resources Information Center

    Schatz, Albert; Kriebs, Jean Oak

    Prepared primarily for junior high school students and utilizing an integrated science approach, this manual offers activities for examining the ecosystem and environmental problems. With organic aspects of soils as the main subject field, it includes study of soil formation, soil fertility, soil contamination, and edaphic relationships. Most of…

  1. U.S. Population Growth: Prospects and Policy.

    ERIC Educational Resources Information Center

    McFalls, Joseph A., Jr.; And Others

    1984-01-01

    The Commission on Population Growth and the American Future concluded that zero population growth (ZPG) is in the best interest of the United States. To achieve ZPG in the future, the United States must keep fertility and net immigration relatively low. Practical problems are discussed. (RM)

  2. Early Adolescent Childbearing: Some Further Notes.

    ERIC Educational Resources Information Center

    Hoeppner, Marie

    Current research on adolescent fertility indicates that illegitimacy is becoming concentrated in the teenage and even preteen years. Increasing sexual activity, lack of contraceptive information and techniques, and a desired pregnancy are possible explanations. Some of the problems faced by adolescent mothers include more complicated pregnancies,…

  3. Banana Gold: Problem or Solution?

    ERIC Educational Resources Information Center

    Joseph, Garnet

    1992-01-01

    Since 1955, the British banana industry has dominated the lives of the Caribs and other peoples in Dominica. Banana growing supplants other economic activities, including local food production; toxic chemicals and fertilizers pollute the land; community is dwindling; suicide is common; and child labor diminishes school attendance. (SV)

  4. Pollution, An Environmental Crisis.

    ERIC Educational Resources Information Center

    Fischer, Richard B.

    This document, written for teachers, outlines the causes and extent of environmental problems relating to air pollution, water pollution, the use of fertilizers and pesticides, land use, and population density. A short bibliography includes references to periodicals and books dealing with teaching methods as well as references for background…

  5. Advances in electron kinetics and theory of gas discharges

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kolobov, Vladimir I.; The University of Alabama in Huntsville, Huntsville, Alabama 35899

    2013-10-15

    “Electrons, like people, are fertile and infertile: high-energy electrons are fertile and able to reproduce.”—Lev TsendinModern physics of gas discharges increasingly uses physical kinetics for analysis of non-equilibrium plasmas. The description of underlying physics at the kinetic level appears to be important for plasma applications in modern technologies. In this paper, we attempt to grasp the legacy of Professor Lev Tsendin, who advocated the use of the kinetic approach for understanding fundamental problems of gas discharges. We outline the fundamentals of electron kinetics in low-temperature plasmas, describe elements of the modern kinetic theory of gas discharges, and show examples ofmore » the theoretical approach to gas discharge problems used by Lev Tsendin. Important connections between electron kinetics in gas discharges and semiconductors are also discussed. Using several examples, we illustrate how Tsendin's ideas and methods are currently being developed for the implementation of next generation computational tools for adaptive kinetic-fluid simulations of gas discharges used in modern technologies.« less

  6. Knowledge, attitude, and practices of infertility among Saudi couples.

    PubMed

    Abolfotouh, Mostafa A; Alabdrabalnabi, Abdullah A; Albacker, Rehab B; Al-Jughaiman, Umar A; Hassan, Samar N

    2013-01-01

    Infertility places a huge psychological burden on infertile couples, especially for women. Greater knowledge of the factors affecting fertility may help to decrease the incidence of infertility by allowing couples to avoid certain risk factors. The aim of our study was (1) to assess the knowledge and attitudes of infertile and fertile Saudi participants on infertility, possible risk factors, and social consequences; and (2) to determine the practices of infertile Saudi couples to promote their fertility before having them attend an in vitro fertilization (IVF) clinic. We conducted a cross-sectional study on 277 fertile participants from outpatient clinics and 104 infertile patients from the IVF clinic at King Abdulaziz Medical City between June 24, 2012 and July 4, 2012, using a previously validated interview questionnaire. Descriptive and analytical statistics were applied with a significance threshold of P ≤ 0.05. A generally poor level of knowledge (59%) and a neutral attitude (76%) toward infertility were reported by participants. Mistaken beliefs commonly held by the study participants regarding the causes of infertility were Djinns and supernatural causes (58.8%), black magic (67.5%), intrauterine devices (71.3%), and contraceptive pills (42.9%). The healer/Sheikh was reported as the primary and secondary preference for infertility treatment by 6.7% and 44.2% of IVF patients, respectively. Compared with fertile patients, IVF patients were significantly less likely to favor divorce (38.5% versus 57.6%; P = 0.001) or marriage to a second wife (62.5% versus 86.2%; P < 0.001), if the woman could not have a baby. The patients with infertility had more favorable attitudes toward fertility drugs (87.5% versus 68.4%; P = 0.003) and having a test tube baby (92.4% versus 70.3%; P < 0.001). Child adoption was accepted as an option for treatment by the majority of IVF patients (60.6%) and fertile outpatients (71.5%). Alternative treatments previously practiced by the IVF patients to improve fertility include practicing Ruqia (61%), using alternative medicine (42%), engaging in physical exercise (39%), eating certain foods (22%), and quitting smoking (12%). These findings have implications for health care providers regarding the reluctance that couples experiencing fertility problems may have, at least initially, to accept some interventions required for the couple to conceive.

  7. Development of a Self-Help Web-Based Intervention Targeting Young Cancer Patients With Sexual Problems and Fertility Distress in Collaboration With Patient Research Partners.

    PubMed

    Winterling, Jeanette; Wiklander, Maria; Obol, Claire Micaux; Lampic, Claudia; Eriksson, Lars E; Pelters, Britta; Wettergren, Lena

    2016-04-12

    The Internet should be suitable for delivery of interventions targeting young cancer patients. Young people are familiar with the technologies, and this patient group is small and geographically dispersed. Still, only few psycho-educational Web-based interventions are designed for this group. Young cancer patients consider reproductive health, including sexuality, an area of great importance and approximately 50% report sexual problems and fertility-related concerns following cancer treatment. Therefore, we set out to develop a self-help Web-based intervention, Fex-Can, to alleviate such problems. To improve its quality, we decided to involve patients and significant others as research partners. The first 18 months of our collaboration are described in this paper. The intervention will subsequently be tested in a feasibility study followed by a randomized controlled trial. The study aims to describe the development of a Web-based intervention in long-term collaboration with patient research partners (PRPs). Ten former cancer patients and two significant others participated in building the Web-based intervention, using a participatory design. The development process is described according to the design step in the holistic framework presented by van Gemert-Pijnen et al and evaluates the PRPs' impact on the content, system, and service quality of the planned intervention. The collaboration between the research group and the PRPs mainly took place in the form of 1-day meetings to develop the key components of the intervention: educational and behavior change content, multimedia (pictures, video vignettes, and audios), interactive online activities (eg, self-monitoring), and partial feedback support (discussion forum, tailored feedback from experts). The PRPs influenced the intervention's content quality in several ways. By repeated feedback on prototypes, the information became more comprehensive, relevant, and understandable. The PRPs gave suggestions concerning the number of exercises and pointed out texts and pictures needing revision (eg, experienced as normative or stereotypical) to increase the persuasiveness of the program. The system quality was improved by PRPs' feedback on design, technical malfunctions, and navigation on the website. Based on feedback about availability of professional support (technical problems and program content), the organization for support was clarified, which increased service quality. The PRPs also influenced the research project on an overall level by suggesting modifications of inclusion criteria for the RCT and by questioning the implementation plan. With suggestions and continuous feedback from PRPs, it was possible to develop a Web-based intervention with persuasive design, believed to be relevant and attractive for young persons with cancer who have sexual problems or fertility distress. In the next step, the intervention will be tested in a feasibility study, followed by an RCT to test the intervention's effectiveness in reducing sexual problems and fertility distress. International Standard Randomized Controlled Trial Number (ISRCTN): 36621459; http://www.isrctn.com/ISRCTN36621459 (Archived by WebCite at http://www.webcitation.org/6gFX40F6T).

  8. Soil zinc and cadmium availability and uptake by wheat (Triticum aestivum L.) as affected by long-term organic matter management

    NASA Astrophysics Data System (ADS)

    Grüter, Roman; Costerousse, Benjamin; Mayer, Jochen; Mäder, Paul; Thonar, Cécile; Frossard, Emmanuel; Schulin, Rainer; Tandy, Susan

    2017-04-01

    Zinc (Zn) deficiency is a widespread problem in human mineral nutrition. It is mainly caused by imbalanced diets with low contents of bioavailable Zn. This is in particular a problem in populations depending on cereals such as wheat (Triticum aestivum L.) as a major source of this essential micronutrient element. Increasing Zn concentrations in wheat grains (biofortification) is therefore an important challenge. At the same time, increased uptake of the toxic heavy metal cadmium (Cd) must be prevented. Agronomic practises influence soil properties such as pH and soil organic carbon and thus also have an indirect effect on phytoavailable soil Zn and Cd concentrations and the uptake of these metals by wheat in addition to direct inputs with fertilizers and other amendments. This study investigated the effects of long-term organic matter management on the phytoavailability of soil Zn and Cd and their uptake by wheat on plots of two Swiss long-term field trials. In one trial (DOK), a farming system comparison trial established in 1978, we compared plots under conventional management with mineral fertilization either in combination or not with farmyard manure application to plots under biodynamic organic management and control plots with no fertilizer application. In the second trial (ZOFE), established in 1949, we compared different fertilizer regimes on conventionally managed plots, including plots with application of mineral fertilizers only, farmyard manure, or compost and control plots with no fertilizer application. Soil physico-chemical and biological properties were determined at the beginning of the growing season. Soil Zn and Cd availabilities were assessed by the Diffusive Gradients in Thin Films (DGT) method and by DTPA extraction before and after wheat cultivation. Additionally, various wheat yield components and element concentrations in shoots and grains were measured at harvest. In the ZOFE trial, soil Zn and Cd concentrations were lowest in the mineral fertilizer and highest in the farmyard manure treatments, where metal export via crop harvests and inputs through farmyard manure dominated soil metal mass balances in the long-term, respectively. DGT-available Zn and Cd correlated negatively with soil pH, total organic carbon and microbial biomass in both trials. They were lowest in the biodynamic and compost treatments and highest in the control treatments. In the ZOFE trial, wheat yields on mineral fertilized plots exceeded the other treatments by more than a factor of two. Cd concentrations in wheat shoots and grains showed a strong positive correlation with DGT-available soil Cd. They were lowest in biodynamic and compost treatments. In contrast, shoot and grain Zn concentrations correlated more closely with total and DTPA-extractable than with DGT-available soil Zn in the ZOFE trial and they poorly correlated with both Zn availability indicators in the DOK trial. Despite these differences, the study reveals that long-term organic matter management has an important influence on the availability of both elements in soil and their uptake by wheat.

  9. Dust Fertilization of the Western Atlantic Biota: a Biochemical Model

    NASA Astrophysics Data System (ADS)

    Holmes, C. W.

    2017-12-01

    Every year an estimated 50 million tons of African dust reaches the Western Atlantic. This dust is composed of quartz sand, clay, and a mixture of quartz and clay particles agglutinated with micronutrient enriched ferruginous cement. However, whether it is friend or foe to biochemical systems is a matter of conjecture. Corals are ideal recorders of changing conditions as the layers can be dated so that the record of chemical changes is easily assessed. There is extensive shallow-and deep water coral development bordering the Florida Straits. The changes in trace element chemistry within these corals show a positive relationship with the African dust record. Recently, it has been demonstrated that many of the metals contained within the dust are necessary micronutrients in the fertilization of plankton. Using the results of these studies, a biochemical model has been constructed. This model suggests a path from inorganic dust through microbial transformation to micronutrient enzymes (i.e. Cd-enriched carbonic anahydrase) and carbonate precipitation on the Bahamian Banks. It is estimated that more than ten million metric tons of this fine, metal-rich sediment is formed each year. However, for much of this sediment, its deposition is temporary, as it is transported into the Florida Straits yearly by tropical cyclones. This metal-enriched fine carbonate becomes nutrients for phytoplankton, providing food for the corals, both shallow and deep.

  10. Little genetic variability in resilience among cattle exists for a range of performance traits across herds in Ireland differing in Fasciola hepatica prevalence.

    PubMed

    Twomey, Alan J; Graham, David A; Doherty, Michael L; Blom, Astrid; Berry, Donagh P

    2018-06-04

    It is anticipated that in the future, livestock will be exposed to a greater risk of infection from parasitic diseases. Therefore, future breeding strategies for livestock, which are generally long-term strategies for change, should target animals adaptable to environments with a high parasitic load. Covariance components were estimated in the present study for a selection of dairy and beef performance traits over herd-years differing in Fasciola hepatica load using random regression sire models. Herd-year prevalence of F. hepatica was determined by using F. hepatica-damaged liver phenotypes which were recorded in abattoirs nationally. The data analyzed consisted up to 83,821 lactation records from dairy cows for a range of milk production and fertility traits, as well as 105,054 young animals with carcass-related information obtained at slaughter. Reaction norms for individual sires were derived from the random regression coefficients. The heritability and additive genetic standard deviations for all traits analyzed remained relatively constant as herd-year F. hepatica prevalence gradient increased up to a prevalence level of 0.7; although there was a large increase in heritability and additive genetic standard deviation for milk and fertility traits in the observed F. hepatica prevalence levels >0.7, only 5% of the data existed in herd-year prevalence levels >0.7. Very little rescaling, therefore, exists across differing herd-year F. hepatica prevalence levels. Within-trait genetic correlations among the performance traits across different herd-year F. hepatica prevalence levels were less than unity for all traits. Nevertheless, within-trait genetic correlations for milk production and carcass traits were all >0.8 for F. hepatica prevalence levels between 0.2 and 0.8. The lowest estimate of within-trait genetic correlations for the different fertility traits ranged from -0.03 (SE = 1.09) in age of first calving to 0.54 (SE = 0.22) for calving to first service interval. Therefore, there was reranking of sires for fertility traits across different F. hepatica prevalence levels. In conclusion, there was little or no genetic variability in sensitivity to F. hepatica prevalence levels among cattle for milk production and carcass traits. But, some genetic variability in sensitivity among dairy cows did exist for fertility traits measured across herds differing in F. hepatica prevalence.

  11. Influence of Radiofrequency Electromagnetic Fields on the Fertility System: Protocol for a Systematic Review and Meta-Analysis.

    PubMed

    Roozbeh, Nasibeh; Abdi, Fatemeh; Amraee, Azadeh; Atarodi Kashani, Zahra; Darvish, Leili

    2018-02-08

    Due to the increased number of users of mobile phones, tablets, and other devices over the past few years, concerns about the potential impact of mobile phones on health are growing. The influence of mobile phone exposure on male fertility has been studied in recent years. Other research has shown that electromagnetic fields (EMFs) increase macrophages in the corpus luteum and growing follicles. Due to conflicting results among studies and since no systematic review has been performed to analyze the effects of radiofrequency EMF exposure from electronic devices on the fertility system in recent years, this evidence-based study is necessary. The main objectives of this study are to determine the best evidence associated with the influence of radiofrequency EMFs on the fertility system and to provide insight into a potential mechanism using our observations. In this systematic review, the databases and gray literature will be searched with no language and date limitation. The following databases will be searched: Cochrane Library, MEDLINE, PubMed, EMBASE, CINAHL, ProQuest, Scopus, Science Direct, Google Scholar, and other Persian databases. The combination of the Medical Subject Heading terms "radiofrequency electromagnetic" and "male reproductive system" or "female reproductive system" will be searched. Observational study designs will be included but case reports, case series, reviews, and letters to the editor will be excluded. Papers selected for retrieval will be evaluated by two independent referees for methodological validation before entering a review using the Newcastle-Ottawa Scale for nonrandomized studies and cohort studies. The results of this study will be submitted to a peer-reviewed journal for publication and also presented at PROSPERO. This systematic review will provide evidence-based data on the effect of radiofrequency EMFs on the fertility system. This article will also classify the harmful effect of radiofrequency waves on primary and secondary infertility. This study could be useful for decreasing infertility. This is important because the rate of infertility is growing, leading to negative outcomes for couples and the health care system. PROSPERO CRD42017072462; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=72462 (Archived by WebCite at http://www.webcitation.org/6wjiE9R2q). ©Nasibeh Roozbeh, Fatemeh Abdi, Azadeh Amraee, Zahra Atarodi Kashani, Leili Darvish. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 08.02.2018.

  12. Water-quality trends in the nation's rivers

    USGS Publications Warehouse

    Smith, R.A.; Alexander, R.B.; Wolman, M.G.

    1987-01-01

    Water-quality records from two nationwide sampling networks now permit nationally consistent analysis of long-term water-quality trends at more than 300 locations on major U.S. rivers. Observed trends in 24 measures of water quality for the period from 1974 to 1981 provide new insight into changes in stream quality that occurred during a time of major changes in both terrestrial and atmospheric influences on surface waters. Particularly noteworthy are widespread decreases in fecal bacteria and lead concentrations and widespread increases in nitrate, chloride, arsenic, and cadmium concentrations. Recorded increases in municipal waste treatment, use of salt on highways, and nitrogen fertilizer application, along with decreases in leaded gasoline consumption and regionally variable trends in coal production and combustion during the period appear to be reflected in water-quality changes.Water-quality records from two nationwide sampling networks now permit nationally consistent analysis of long-term water-quality trends at more than 300 locations on major U. S. rivers. Observed trends in 24 measures of water quality for the period from 1974 to 1981 provide new insight into changes in stream quality that occurred during a time of major changes in both terrestrial and atmospheric influences on surface waters. Particularly noteworthy are widespread decreases in fecal bacteria and lead concentrations and widespread increases in nitrate, chloride, arsenic, and cadmium concentrations. Recorded increases in municipal waste treatment, use of salt on highways, and nitrogen fertilizer application, along with decreases in leaded gasoline consumption and regionally variable trends in coal production and combustion during the period appear to be reflected in water-quality changes.

  13. Export fluxes in a naturally iron-fertilized area of the Southern Ocean - Part 1: Seasonal dynamics of particulate organic carbon export from a moored sediment trap

    NASA Astrophysics Data System (ADS)

    Rembauville, M.; Salter, I.; Leblond, N.; Gueneugues, A.; Blain, S.

    2015-06-01

    A sediment trap moored in the naturally iron-fertilized Kerguelen Plateau in the Southern Ocean provided an annual record of particulate organic carbon and nitrogen fluxes at 289 m. At the trap deployment depth, current speeds were typically low (~ 10 cm s-1) and primarily tidal-driven (M2 tidal component). Although advection was weak, the sediment trap may have been subject to hydrodynamical and biological (swimmer feeding on trap funnel) biases. Particulate organic carbon (POC) flux was generally low (< 0.5 mmol m-2 d-1), although two episodic export events (< 14 days) of 1.5 mmol m-2 d-1 were recorded. These increases in flux occurred with a 1-month time lag from peaks in surface chlorophyll and together accounted for approximately 40% of the annual flux budget. The annual POC flux of 98.2 ± 4.4 mmol m-2 yr-1 was low considering the shallow deployment depth but comparable to independent estimates made at similar depths (~ 300 m) over the plateau, and to deep-ocean (> 2 km) fluxes measured from similarly productive iron-fertilized blooms. Although undertrapping cannot be excluded in shallow moored sediment trap deployment, we hypothesize that grazing pressure, including mesozooplankton and mesopelagic fishes, may be responsible for the low POC flux beneath the base of the winter mixed layer. The importance of plankton community structure in controlling the temporal variability of export fluxes is addressed in a companion paper.

  14. Effect of season, month of parturition and lactation on estrus behavior and ovarian activity in Barki x Rahmani crossbred ewes under subtropical conditions.

    PubMed

    Hashem, N M; El-Zarkouny, S Z; Taha, T A; Abo-Elezz, Z R

    2011-04-15

    The correlations between some meteorological parameters and fertility data were evaluated in Barki x Rahmani crossbred ewes using the records of five consecutive years (2003-2007). Additionally, estrus detection and ultrasonic evaluation were applied on eighteen mature dry ewes during breeding and non-breeding seasons. The effect of lactation was evaluated by monitoring estrus behavior in ninety four lactating ewes from 40 to 120 d after parturition. Moreover, ultrasonography was used to identify ovarian activity in six cyclic and six acyclic non-lactating ewes. Results revealed that relative estrus occurrence and fertile mating were positively correlated (P <0.05) with high temperature and long photoperiod (conditions of summer season), and were negatively correlated (P < 0.01) with rainfall (condition of winter season). During breeding season, estrus rate, serum progesterone concentration, and diameter of largest follicle were significantly (P < 0.05) higher than those observed during the non-breeding season. Furthermore, month of parturition had a significant effect (P < 0.05) on estrus rate of lactating ewes where ewes that lambed in August, September, and October recorded higher estrus rate than those lambed in November and December. However, the lactational strength did not exert any deleterious effect on the reproductive performance of lactating ewes. In conclusion, in Egypt under subtropical conditions, Barki x Rahmani crossbred ewes exerted optimum estrus behavior and fertile mating during summer season. The reduction in estrus activity during lactation was due to the seasonal effect rather than lactational stress. Copyright © 2011 Elsevier Inc. All rights reserved.

  15. [Andrologic disease detected during army medical visit].

    PubMed

    Campodonico, Fabio; Michelazzi, Alberto; Capurro, Anna; Carmignani, Giorgio

    2003-12-01

    Aim of this study is to investigate the prevalence of andrologic diseases in young men (age 18 years) recruited for conscription in a north-western Italian region. A random sample of 1993 young men was evaluated at the Army Medical Visit Center of the Military District of Genoa. The visits were performed by the same doctor. An examination of external genitalia and secondary sex characters was made and the medical history of each conscript was recorded. Investigation procedures were standardized according to the guidelines of the WHO for the diagnosis and management of the infertile male. Andrologic disorders were found in 547 subjects (27.5%) and first diagnosed in 412 (20.7%). Specific acquired or congenital disorders are discussed. Some patients with most significant diseases were referred to the Urologic Department for second level diagnostic exams. This study underlines the role of the army medical visit as a tool for andrologic screening in young males. The military health service may be a relevant institution for postpuberal control and it could be useful to prevent future sexual and fertility problems in adult males.

  16. Compulsory Birth Control and Fertility Measures in India.

    ERIC Educational Resources Information Center

    Halli, S. S.

    1983-01-01

    Discussion of possible applications of the microsimulation approach to analysis of population policy proposes compulsory sterilization policy for all of India. Topics covered include India's population problem, methods for generating a distribution of couples to be sterilized, model validation, data utilized, data analysis, program limitations,…

  17. The Federal Program in Population Research, Parts 1 and 2.

    ERIC Educational Resources Information Center

    Federal Council for Science and Technology, Washington, DC.

    The first part of this report characterizes the many facets of the population problem (including biological, economic, and social aspects), suggests a list of areas in which the Federal Government should emphasize research (reproductive biology; fertility regulation techniques and materials; description, determinants, consequences of population…

  18. COMPI Fertility Problem Stress Scales is a brief, valid and reliable tool for assessing stress in patients seeking treatment.

    PubMed

    Sobral, Maria P; Costa, Maria E; Schmidt, Lone; Martins, Mariana V

    2017-02-01

    Are the Copenhagen Multi-Centre Psychosocial Infertility research program Fertility Problem Stress Scales (COMPI-FPSS) a reliable and valid measure across gender and culture? The COMPI-FPSS is a valid and reliable measure, presenting excellent or good fit in the majority of the analyzed countries, and demonstrating full invariance across genders and partial invariance across cultures. Cross-cultural and gender validation is needed to consider a measure as standard care within fertility. The present study is the first attempting to establish comparability of fertility-related stress across genders and countries. Cross-sectional study. First, we tested the structure of the COMPI-FPSS. Then, reliability and validity (convergent and discriminant) were examined for the final model. Finally, measurement invariance both across genders and cultures was tested. Our final sample had 3923 fertility patients (1691 men and 2232 women) recruited in clinical settings from seven different countries: Denmark, China, Croatia, Germany, Greece, Hungary and Sweden. Participants had a mean age of 34 years and the majority (84%) were childless. Findings confirmed the original three-factor structure of the COMPI-FPSS, although suggesting a shortened measurement model using less items that fitted the data better than the full version model. While data from the Chinese and Croatian subsamples did not fit, all other counties presented good fit (χ 2 /df ≤ 5.4; comparative fit index ≥ 0.94; root-mean-square error of approximation ≤ 0.07; modified expected cross-validation index ≤ 0.77). In general, reliability, convergent validity, and discriminant validity were observed in all subscales from each country (composite reliability ≥ 0.63; average variance extracted ≥ 0.38; squared correlation ≥ 0.13). Full invariance was established across genders, and partial invariance was demonstrated across countries. Generalizability regarding the validation of the COMPI-FPSS cannot be made regarding infertile individuals not seeking treatment, or non-European patients. This study did not investigate predictive validity, and hence the capability of this instrument in detecting changes in fertility-specific adjustment over time and predicting the psychological impact needs to be established in future research. Besides extending knowledge on the psychometric properties of one of the most used fertility stress questionnaire, this study demonstrates both research and clinical usefulness of the COMPI-FPSS. This study was supported by European Union Funds (FEDER/COMPETE-Operational Competitiveness Program, and by national funds (FCT-Portuguese Foundation for Science and Technology) under the projects PTDC/MHC-PSC/4195/2012 and SFRH/BPD/85789/2012). There are no conflicts of interest to declare. N/A. © The Author 2016. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  19. Effects of seawater acidification on early development of the intertidal sea urchin Paracentrotus lividus (Lamarck 1816).

    PubMed

    Moulin, Laure; Catarino, Ana Isabel; Claessens, Thomas; Dubois, Philippe

    2011-01-01

    The effect of pH ranging from 8.0 to 6.8 (total scale - pH(T)) on fertilization, cleavage and larval development until pluteus stage was assessed in an intertidal temperate sea urchin. Gametes were obtained from adults collected in two contrasting tide pools, one showing a significant nocturnal pH decrease (lowest pH(T)=7.4) and another where pH was more stable (lowest pH(T)=7.8). The highest pH(T) at which significant effects on fertilization and cleavage were recorded was 7.6. On the contrary, larval development was only affected below pH(T) 7.4, a value equal or lower than that reported for several subtidal species. This suggests that sea urchins inhabiting stressful intertidal environments produce offspring that may better resist future ocean acidification. Moreover, at pH(T) 7.4, the fertilization rate of gametes whose progenitors came from the tide pool with higher pH decrease was significantly higher, indicating a possible acclimatization or adaptation of gametes to pH stress. Copyright © 2010 Elsevier Ltd. All rights reserved.

  20. Parameters of microbial respiration in soils of the impact zone of a mineral fertilizer factory

    NASA Astrophysics Data System (ADS)

    Zhukova, A. D.; Khomyakov, D. M.

    2015-08-01

    The carbon content in the microbial biomass and the microbial production of CO2 (the biological component of soil respiration) were determined in the upper layer (0-10 cm) of soils in the impact zone of the OJSC Voskresensk Mineral Fertilizers, one of the largest factories manufacturing mineral fertilizers in Russia. Statistical characteristics and schematic distribution of the biological parameters in the soil cover of the impact zone were analyzed. The degree of disturbance of microbial communities in the studied objects varied from weak to medium. The maximum value (0.44) was observed on the sampling plot 4 km away from the factory and 0.5 km away from the place of waste (phosphogypsum) storage. Significantly lower carbon content in the microbial biomass and its specific respiration were recorded in the agrosoddy-podzolic soil as compared with the alluvial soil sampled at the same distance from the plant. The effects of potential soil pollutants (fluorine, sulfur, cadmium, and stable strontium) on the characteristics of soil microbial communities were described with reliable regression equations.

  1. Changes in women's attractiveness perception of masculine men's dances across the ovulatory cycle: preliminary data.

    PubMed

    Cappelle, Tessa; Fink, Bernhard

    2013-10-10

    Women's preferences for putative cues of genetic quality in men's voices, faces, bodies, and behavioral displays are stronger during the fertile phase of the ovulatory cycle. Here we show that ovulatory cycle-related changes in women's attractiveness perceptions of male features are also found with dance movements, especially those perceived as highly masculine. Dance movements of 79 British men were recorded with an optical motion-capture system whilst dancing to a basic rhythm. Virtual humanoid characters (avatars) were created and converted into 15-second video clips and rated by 37 women on masculinity. Another 23 women judged the attractiveness of the 10 dancers who scored highest and those 10 who scored lowest on masculinity once in days of high fertility and once in days of low fertility of their ovulatory cycle. High-masculine dancers were judged higher on attractiveness around ovulation than on other cycle days, whilst no such perceptual difference was found for low-masculine dancers. We suggest that women may gain fitness benefits from evolved preferences for masculinity cues they obtain from male dance movements.

  2. Spent mushroom substrate biochar as a potential amendment in pig manure and rice straw composting processes.

    PubMed

    Chang, Ken-Lin; Chen, Xi-Mei; Sun, Jian; Liu, Jing-Yong; Sun, Shui-Yu; Yang, Zuo-Yi; Wang, Yin

    2017-07-01

    Spent mushroom substrate (SMS) is a bulky waste byproduct of commercial mushroom production, which can cause serious environmental problems and, therefore, poses a significant barrier to future expansion of the mushroom industry. In the present study, we explored the use of SMS as a biochar to improve the quality of bio-fertilizer. Specifically, we performed a series of experiments using composting reactors to investigate the effects of SMS biochar on the physio-chemical properties of bio-fertilizer. Biochar was derived from dry SMS pyrolysed at 500°C and mixed with pig manure and rice straw. Results from this study demonstrate that the addition of biochar significantly reduced electrical conductivity and loss of organic matter in compost material. Nutrient analysis revealed that the SMS-derived biochar is rich in fertilizer nutrients such as P, K, Na, and N. All of these findings suggest that SMS biochar could be an excellent medium for compost.

  3. Responses to warnings about the impact of eating disorders on fertility: a qualitative study.

    PubMed

    Holmes, Su

    2018-05-01

    Eating disorders (EDs) have often been discussed as a risk to reproductive health. But existing research is quantitative in nature, paying no attention to issues of patient experience. In discussing data from 24 semi-structured interviews, this article draws on sociological approaches to medical 'risk' and feminist approaches to EDs to explore how women with experience of an ED responded to fertility warnings within treatment contexts. In doing so, it is suggested that responses to fertility warnings offer unique insight into the potentially damaging limitations of biomedical approaches to eating problems and their focus on EDs as individual 'pathologies' (rather than culturally embedded expressions of gendered embodiment). At best warnings are seen as making problematic assumptions about the aspirations of female patients, which may curtail feelings of agency and choice. At worst, they may push women further into destructive bodily and eating practices, and silence the distress that may be articulated by an ED. © 2018 Foundation for the Sociology of Health & Illness.

  4. [Oncofertility: a new focus in women health-care...].

    PubMed

    Chevalier, N; Dewailly, Didier; Fenichel, Patrick

    2009-09-01

    Although treatment and survival are the primary focus of health-care patients, with cancer survivors living longer it is now appropriate to consider their quality of life after treatment, including the possibility of becoming parents. There are several options for fertility preservation in cancer patients. Even though most of them are still experimental and their efficacy and reliability have not been determined, especially in women. The most successful alternative for female survivors is embryo cryopreservation, an approach not suitable for many single or virgin women or even possible for prepubertal girls. Reports of live birth after transplantation of human ovarian tissue have reinforced the clinical potential of ovarian tissue banking for fertility preservation. Many exciting studies are underway to improve the efficacy and solve the problems with current fertility preservation strategies, especially for in vitro culture of cryopreserved tissue or follicles. Continuous efforts to improve current strategies and to develop new strategies will benefit many women and children who are facing premature ovarian failure and sterility.

  5. Human immunodeficiency virus/acquired immunodeficiency syndrome and infertility: emerging problems in the era of highly active antiretrovirals.

    PubMed

    Kushnir, Vitaly A; Lewis, William

    2011-09-01

    To review the effects of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) in terms of its associated comorbid conditions and the side effects of antiretroviral treatment on fertility. PubMed computer search to identify relevant articles. Research institution. None. None. None. Biological alterations in reproductive physiology may account for subfertility in patients infected with HIV. Psychosocial factors in patients with HIV infection may affect their reproductive desires and outcomes. Antiretroviral medications may have direct toxicity on gametes and embryos. Available evidence indicates that fertility treatments can be a safe option for couples with HIV-discordant infection status, although the potential risk of viral transmission cannot be completely eliminated. Because their potential reproductive desires are increasingly becoming a concern in the health care of young HIV-infected patients, additional data are needed to address the effect of HIV and its treatments on their fertility and reproductive outcomes. Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  6. The effect of fertility stress on endometrial and subendometrial blood flow among infertile women.

    PubMed

    Dong, Yuezhi; Cai, Yanna; Zhang, Yu; Xing, Yurong; Sun, Yingpu

    2017-03-04

    To investigate the effect of fertility stress on endometrial and subendometrial blood flow among infertile women. This case-control study was conducted in The First Affiliated Hospital of Zhengzhou University. The fertility problem inventory (FPI) was adopted to evaluate fertility stress. Three-dimensional power Doppler ultrasonography (3D PD-US) was performed during the proliferative phase of the menstrual cycle (days 5-11) to measure endometrial thickness, pattern, endometrial and subendometrial volume (V), the vascularization index (VI), the flow index (FI) and the vascularization-FI (VFI) index. Then, 300 infertile women were separated into two groups (high-score group and low-score group) based on total FPI scores and 80 healthy women were selected as controls. No differences were found among all three groups with regard to general characteristics, endometrial thickness, pattern, endometrial and subendometrial V, VI and VFI. The endometrial and subendometrial FIs associated with different stress levels significantly differed among the three groups (F = 33.95, P < 0.001; F = 44.79, P < 0.001, respectively). The endometrial and subendometrial FIs in the control group were significantly higher than those in the high-score group and low-score groups. The endometrial and subendometrial FIs in the low-score group were significantly higher than those in the high-score group. The total FPI score was closely related to the endometrial and subendometrial FIs (r = -0.304, P < 0.001; r = -0.407, P < 0.001, respectively). Fertility stress was associated with endometrial and subendometrial flow index. Whether fertility stress might affect pregnancy outcome by reducing endometrial and subendometrial blood flow requires further research.

  7. Evaluating The Effect of Melatonin on HAS2, and PGR expression, as well as Cumulus Expansion, and Fertility Potential in Mice.

    PubMed

    Ezzati, Maryam; Roshangar, Leila; Soleimani Rad, Jafar; Karimian, Nahid

    2018-04-01

    Infertility is a worldwide health problem which affects approximately 15% of sexually active couples. One of the factors influencing the fertility is melatonin. Also, protection of oocytes and embryos from oxidative stress inducing chemicals in the culture medium is important. The aim of the present study was to investigate if melatonin could regulate hyaluronan synthase-2 (HAS2) and Progesterone receptor (PGR) expressions in the cumulus cells of mice oocytes and provide an in vitro fertilization (IVF) approach. In this experimental study, for this purpose, 30 adult female mice and 15 adult male mice were used. The female mice were superovulated using 10 U of pregnant mare serum gonadotropin (PMSG) and 24 hours later, 10 U of human chorionic gonadotropin (hCG) were injected. Next, cumulus oocyte complexes (COCs) were collected from the oviducts of the female mice by using a matrix-flushing method. The cumulus cells were cultured with melatonin 10 μM for 6 hours and for real-time reverse transcription-polymerase chain reaction (RT-PCR) was used for evaluation of HAS2 and PGR expression levels. The fertilization rate was evaluated through IVF. All the data were analyzed using a t test. The results of this study showed that HAS2 and PGR expressions in the cumulus cells of the mice receiving melatonin increased in comparison to the control groups. Also, IVF results revealed an enhancement in fertilization rate in the experimental groups compared to the control groups. To improve the oocyte quality and provide new approaches for infertility treatment, administration of melatonin as an antioxidant, showed promising results. Thus, it is concluded that fertility outcomes can be improved by melatonin it enhances PGR. Copyright© by Royan Institute. All rights reserved.

  8. IMPAIRED FERTILITY AND PERCEIVED DIFFICULTIES CONCEIVING IN GHANA: MEASUREMENT PROBLEMS AND PROSPECTS.

    PubMed

    Fledderjohann, Jasmine; Johnson, David R

    2016-08-01

    What is the most appropriate measure of impaired fertility for understanding its social consequences in sub-Saharan Africa? The dearth of subjective measures in surveys in the region has prevented comparisons of subjective and objective measures. Perceived difficulties conceiving may have a greater impact than objective measures for social outcomes such as divorce, stigmatization and distress. This study compares 12- (clinical) and 24- (epidemiological) month measures from biomedicine and 5- and 7-year measures from demography with a subjective measure of impaired fertility using correlations, random effects models and test-retest models to assess relationships between measures, their association with sociodemographic characteristics and the stability of measures across time. Secondary panel data (1998-2004) from 1350 Ghanaian women aged 15-49 of all marital statuses are used. Longer waiting times to identification of impaired fertility required by demographic measures result in more stable measures, but perceived difficulties conceiving are most closely aligned with clinical infertility (r=0.61; p<0.05). Epidemiological infertility is also closely aligned with the subjective measure. A large proportion of those identified as having impaired fertility based purely on waiting times are successful contraceptors. Where subjective measures are not available, epidemiological (24-month) measures may be most appropriate for studies of the social consequences of impaired fertility. Accounting for contraceptive use is important in order to avoid false positives. Future research should consider a variety of measures of perceived difficulties conceiving and self-identified infertility to assess which is most valid; in order to accomplish this, it is imperative that subjective measures of infertility be included in social surveys in sub-Saharan Africa.

  9. Modeling Phosphorous Losses from Seasonal Manure Application Schemes

    NASA Astrophysics Data System (ADS)

    Menzies, E.; Walter, M. T.

    2015-12-01

    Excess nutrient loading, especially nitrogen and phosphorus, to surface waters is a common and significant problem throughout the United States. While pollution remediation efforts are continuously improving, the most effective treatment remains to limit the source. Appropriate timing of fertilizer application to reduce nutrient losses is currently a hotly debated topic in the Northeastern United States; winter spreading of manure is under special scrutiny. We plan to evaluate the loss of phosphorous to surface waters from agricultural systems under varying seasonal fertilization schemes in an effort to determine the impacts of fertilizers applied throughout the year. The Cayuga Lake basin, located in the Finger Lakes region of New York State, is a watershed dominated by agriculture where a wide array of land management strategies can be found. The evaluation will be conducted on the Fall Creek Watershed, a large sub basin in the Cayuga Lake Watershed. The Fall Creek Watershed covers approximately 33,000 ha in central New York State with approximately 50% of this land being used for agriculture. We plan to use the Soil and Water Assessment Tool (SWAT) to model a number of seasonal fertilization regimes such as summer only spreading and year round spreading (including winter applications), as well as others. We will use the model to quantify the phosphorous load to surface waters from these different fertilization schemes and determine the impacts of manure applied at different times throughout the year. More detailed knowledge about how seasonal fertilization schemes impact phosphorous losses will provide more information to stakeholders concerning the impacts of agriculture on surface water quality. Our results will help farmers and extensionists make more informed decisions about appropriate timing of manure application for reduced phosphorous losses and surface water degradation as well as aid law makers in improving policy surrounding manure application.

  10. Development of a novel allele-specific Rfo marker and creation of Ogura CMS fertility-restored interspecific hybrids in Brassica oleracea.

    PubMed

    Yu, Hai-Long; Fang, Zhi-Yuan; Liu, Yu-Mei; Yang, Li-Mei; Zhuang, Mu; Lv, Hong-Hao; Li, Zhan-Sheng; Han, Feng-Qing; Liu, Xiao-Ping; Zhang, Yang-Yong

    2016-08-01

    A novel allele-specific Rfo marker was developed and proved to be effective for MAS of Rfo gene in B. oleracea background and six Ogu-CMS fertility-restored interspecific hybrids were created for the first time. Ogura cytoplasmic male sterility (Ogu-CMS) has been extensively used for Brassica oleracea hybrid production. However, because of maternal inheritance, all the hybrids produced by CMS lines are male sterile and cannot be self-pollinated, which prohibits germplasm maintenance and innovation. This problem can be overcome by using the Ogu-CMS restorer line, but restorer material is absent in B. oleracea crops. Here, Rfo, a fertility-restored gene of Ogu-CMS, was transferred from rapeseed restorer lines into a Chinese kale Ogu-CMS line using interspecific hybridization combined with embryo rescue. Nine interspecific, triploid plant progenies were identified at morphological and ploidy level, with phenotypes intermediate between those of rapeseed and Chinese kale. Because the Rfo marker (Hu et al., Mol Breeding 22:663-674, 2008) cannot distinguish the Rfo and its homologies under a B. oleracea background, a novel allele-specific Rfo marker was developed based on the BLAST analysis of highly homologous Rfo sequences in B. oleracea. Screening using the novel Rfo marker found that six interspecific hybrids carrying Rfo were also fertile, although fertility varied during different flowering periods. Furthermore, BC1 offsprings with the Rfo gene were selected with the allele-specific Rfo marker and showed restored fertility. These results indicated that the novel allele-specific marker could be used for the MAS of Rfo gene in B. oleracea, and this study lays the foundation for the development of Ogu-CMS restorer material in cabbage and its related other subspecies.

  11. Trees' role in nitrogen leaching after organic, mineral fertilization: a greenhouse experiment.

    PubMed

    López-Díaz, M L; Rolo, V; Moreno, G

    2011-01-01

    New sustainable agriculture techniques are arising in response to the environmental problems caused by intensive agriculture, such as nitrate leaching and surface water eutrophication. Organic fertilization (e.g., with sewage sludge) and agroforestry could be used to reduce nutrient leaching. We assessed the efficiency of establishing trees and pasture species in environmentally sensitive, irrigated Mediterranean grassland soils in controlling nitrate leaching. Four vegetation systems-bare soil, pasture species, cherry trees [ (L.) L.], and pasture-tree mixed plantings-and five fertilization treatments-control, two doses of mineral fertilizer, and two doses of organic fertilizer (sewage sludge)-were tested in a greenhouse experiment over 2 yr. In the experiment, the wet and warm climate characteristics of Mediterranean irrigated croplands and the plant-to-plant and soil-to-plant interactions that occur in open-field agroforestry plantations were simulated. Following a factorial design with six replicates, 120 pots (30-cm radius and 120 cm deep) were filled with a sandy, alluvial soil common in the cultivated fluvial plains of the region. The greatest pasture production and tree growth were obtained with sewage sludge application. Both pasture production and tree growth decreased significantly in the pasture-tree mixed planting. Nitrate leaching was negligible in this latter treatment, except under the highest dose of sewage sludge application. The rapid mineralization of sludge suggested that this organic fertilizer should be used very cautiously in warm, irrigated Mediterranean soils. Mixed planting of pasture species and trees, such as , could be a useful tool for mitigating nitrate leaching from irrigated Mediterranean pastures on sandy soils. American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America.

  12. Enhanced accumulation of copper and lead in amaranth (Amaranthus paniculatus), Indian mustard (Brassica juncea) and sunflower (Helianthus annuus).

    PubMed

    Rahman, Motior M; Azirun, Sofian M; Boyce, Amru N

    2013-01-01

    Soil contamination by copper (Cu) and lead (Pb) is a widespread environmental problem. For phytoextraction to be successful and viable in environmental remediation, strategies that can improve plant uptake must be identified. In the present study we investigated the use of nitrogen (N) fertilizer as an efficient way to enhance accumulation of Cu and Pb from contaminated industrial soils into amaranth, Indian mustard and sunflower. Plants were grown in a greenhouse and fertilized with N fertilizer at rates of 0, 190 and 380 mg kg⁻¹ soil. Shoots, roots and total accumulation of Cu and Pb, transfer factor (TF), translocation index were assessed to evaluate the transport and translocation ability of tested plants. Addition of N fertilizer acidified the industrial soil and caused the pH to decrease to 5.5 from an initial pH of 6.9. Industrial soil amended with N fertilizer resulted in the highest accumulation of Pb and Cu (for Pb 10.1-15.5 mg kg⁻¹, for Cu 11.6-16.8 mg kg⁻¹) in the shoots, which was two to four folds higher relative to the concentration in roots in all the three plants used. Sunflower removed significantly higher Pb (50-54%) and Cu (34-38%) followed by amaranth and Indian mustard from industrial soils with the application of N fertilizer. The TF was <1 while the shoot and root concentration (SC/RC) ratios of Pb and Cu were between 1.3-4.3 and 1.8-3.8, respectively, regardless of plant species. Sunflower is the best plant species to carry out phytoextraction of Pb and Cu. In contrast, Pb and Cu removal by Indian mustard and amaranth shows great potential as quick and short duration vegetable crops. The results suggest that the application of N fertilizer in contaminated industrial soil is an effective amendment for the phytoextraction of Pb and Cu from contaminated industrial soils.

  13. Synthesis of a novel slow-release potassium fertilizer from modified Pidgeon magnesium slag by potassium carbonate.

    PubMed

    Li, Yongling; Cheng, Fangqin

    2016-08-01

    A novel slow-release potassium fertilizer (SPF) was synthesized using Pidgeon magnesium slag (PMS) and potassium carbonate, which could minimize fertilizer nutrient loss and PMS disposal problems. Orthogonal experiments were conducted to determine the optimum conditions for synthesis. The potassium (K)-bearing compounds of SPF existed mainly in the form of crystalline phases Ca1.197K0.166SiO4, K2MgSiO4, and K4CaSi3O9, and in the noncrystalline phase. The active silicon content of SPF was 2.09 times as much as that of magnesium slag, and the slow-release character of SPF met the requirement for partly slow-release fertilizer in the national standard (GB/T23348-2009). The best models for describing the K release kinetics in water and 2% citric acid were the Elovich model and the first-order model, respectively. The heavy metal contents of SPF conformed to the national standard for organic-inorganic compound fertilizers, and the leaching mass concentrations of heavy metals and Fluorine were far lower than the limit values of the identification standard for hazardous waste identification for extraction toxicity (GB5085.3-2007), and also met the class II quality standard for ground water. The environmental risk of SPF is therefore very low, but because SPF is alkaline, its effect on soil pH should be taken into account. PMS is the solid waste resulting from the production of magnesium metal by Pidgeon's reduction process. Utilization of PMS in the high-technology and high-value areas may promote the high-efficiency development of worldwide collection metallic magnesium industry and contribute to the reduction of emissions of fine dust to air. This paper presents one of the new techniques in the use of PMS as a slow-release fertilizer by adding K2CO3. The product can serve as a very cost-effective and reliable artificial fertilizer.

  14. A HyperSpectral Imaging (HSI) approach for bio-digestate real time monitoring

    NASA Astrophysics Data System (ADS)

    Bonifazi, Giuseppe; Fabbri, Andrea; Serranti, Silvia

    2014-05-01

    One of the key issues in developing Good Agricultural Practices (GAP) is represented by the optimal utilisation of fertilisers and herbicidal to reduce the impact of Nitrates in soils and the environment. In traditional agriculture practises, these substances were provided to the soils through the use of chemical products (inorganic/organic fertilizers, soil improvers/conditioners, etc.), usually associated to several major environmental problems, such as: water pollution and contamination, fertilizer dependency, soil acidification, trace mineral depletion, over-fertilization, high energy consumption, contribution to climate change, impacts on mycorrhizas, lack of long-term sustainability, etc. For this reason, the agricultural market is more and more interested in the utilisation of organic fertilisers and soil improvers. Among organic fertilizers, there is an emerging interest for the digestate, a sub-product resulting from anaerobic digestion (AD) processes. Several studies confirm the high properties of digestate if used as organic fertilizer and soil improver/conditioner. Digestate, in fact, is somehow similar to compost: AD converts a major part of organic nitrogen to ammonia, which is then directly available to plants as nitrogen. In this paper, new analytical tools, based on HyperSpectral Imaging (HSI) sensing devices, and related detection architectures, is presented and discussed in order to define and apply simple to use, reliable, robust and low cost strategies finalised to define and implement innovative smart detection engines for digestate characterization and monitoring. This approach is finalized to utilize this "waste product" as a valuable organic fertilizer and soil conditioner, in a reduced impact and an "ad hoc" soil fertilisation perspective. Furthermore, the possibility to contemporary utilize the HSI approach to realize a real time physicalchemical characterisation of agricultural soils (i.e. nitrogen, phosphorus, etc., detection) could allow to set up "real time" selective fertilization strategies in order to obtain a safer culture production.

  15. Exploitation of genetic and physiological determinants of embryonic resistance to elevated temperature to improve embryonic survival in dairy cattle during heat stress.

    PubMed

    Hansen, P J

    2007-09-01

    Heat stress causes large reductions in fertility in lactating dairy cows. The magnitude and geographical extent of this problem is increasing because improvements in milk yield have made it more difficult for cows to regulate body temperature during warm weather. There have been efforts to improve fertility during heat stress by exploiting determinants of oocyte and embryonic responses to elevated temperature. Among these determinants are genotype, stage of development, and presence of cytoprotective molecules in the reproductive tract. One effective strategy for increasing pregnancy rate during heat stress is to use embryo transfer to bypass effects of elevated temperature on the oocyte and early embryo. Pregnancy success to embryo transfer in the summer can be further improved by exposure of embryos to insulin-like growth factor-I during culture before transfer. Among the cytoprotective molecules that have been examined for enhancing fertility during heat stress are bovine somatotropin and various antioxidants. To date, an effective method for delivery of these molecules to increase fertility during heat stress has not been identified. Genes in cattle exist for regulation of body temperature and for cellular resistance to elevated temperature. Although largely unidentified, the existence of these genes offers the possibility for their incorporation into dairy breeds through crossbreeding or on an individual-gene basis. In summary, physiological or genetic manipulation of the cow to improve embryonic resistance to elevated temperature is a promising approach for enhancing fertility of lactating dairy cows.

  16. Subcritical hydrothermal treatment for the recovery of liquid fertilizer from scallop entrails.

    PubMed

    Hwang, In-Hee; Aoyama, Hiroya; Abe, Natsuki; Matsuo, Takayuki; Matsuto, Toshihiko

    2015-01-01

    Scallop entrails are organic wastes containing abundant proteins and minerals but are considered difficult to recycle because of high cadmium concentrations. In this work, the current problem of scallop entrails recycling was investigated and a subcritical hydrothermal treatment (SCHT) was examined for the recovery of liquid fertilizer from scallop entrails. Scallop entrails are mainly recycled for composting and feedstuff production. However, the dilution by mixing scallop entrails with other feed waste was the sole countermeasure to reduce the cadmium concentration of compost. For feedstuff production, whole product derived from scallop entrails was exported to other countries instead of domestic utilization. Temperature, retention time (RT) at given temperature, and liquid-to-solid (LS) ratio were examined as SCHT conditions for scallop entrails processing. The extraction ratio of each constituent mainly depends on the temperature rather than the RT or the LS ratio. Upon the SCHT of scallop entrails at 200°C, an RT of 20 min, and an LS ratio of 10, the extraction of fertilizer constituents such as nitrogen, phosphorus, and potassium from the liquid product was optimum, whereas the release of cadmium was suppressed. The concentrations of heavy metals in the liquid product obtained using the above-mentioned SCHT conditions were below the maximum permissible concentration stipulated by the Fertilizer Control Law. SCHT is considered to be a feasible recycling method for scallop entrails to recover fertilizer components with a concomitant separation of cadmium from the product.

  17. A wheat CCAAT box-binding transcription factor increases the grain yield of wheat with less fertilizer input.

    PubMed

    Qu, Baoyuan; He, Xue; Wang, Jing; Zhao, Yanyan; Teng, Wan; Shao, An; Zhao, Xueqiang; Ma, Wenying; Wang, Junyi; Li, Bin; Li, Zhensheng; Tong, Yiping

    2015-02-01

    Increasing fertilizer consumption has led to low fertilizer use efficiency and environmental problems. Identifying nutrient-efficient genes will facilitate the breeding of crops with improved fertilizer use efficiency. This research performed a genome-wide sequence analysis of the A (NFYA), B (NFYB), and C (NFYC) subunits of Nuclear Factor Y (NF-Y) in wheat (Triticum aestivum) and further investigated their responses to nitrogen and phosphorus availability in wheat seedlings. Sequence mining together with gene cloning identified 18 NFYAs, 34 NFYBs, and 28 NFYCs. The expression of most NFYAs positively responded to low nitrogen and phosphorus availability. In contrast, microRNA169 negatively responded to low nitrogen and phosphorus availability and degraded NFYAs. Overexpressing TaNFYA-B1, a low-nitrogen- and low-phosphorus-inducible NFYA transcript factor on chromosome 6B, significantly increased both nitrogen and phosphorus uptake and grain yield under differing nitrogen and phosphorus supply levels in a field experiment. The increased nitrogen and phosphorus uptake may have resulted from the fact that that overexpressing TaNFYA-B1 stimulated root development and up-regulated the expression of both nitrate and phosphate transporters in roots. Our results suggest that TaNFYA-B1 plays essential roles in root development and in nitrogen and phosphorus usage in wheat. Furthermore, our results provide new knowledge and valuable gene resources that should be useful in efforts to breed crops targeting high yield with less fertilizer input. © 2015 American Society of Plant Biologists. All Rights Reserved.

  18. A Wheat CCAAT Box-Binding Transcription Factor Increases the Grain Yield of Wheat with Less Fertilizer Input1

    PubMed Central

    Qu, Baoyuan; He, Xue; Wang, Jing; Zhao, Yanyan; Teng, Wan; Shao, An; Zhao, Xueqiang; Ma, Wenying; Wang, Junyi; Li, Bin; Li, Zhensheng; Tong, Yiping

    2015-01-01

    Increasing fertilizer consumption has led to low fertilizer use efficiency and environmental problems. Identifying nutrient-efficient genes will facilitate the breeding of crops with improved fertilizer use efficiency. This research performed a genome-wide sequence analysis of the A (NFYA), B (NFYB), and C (NFYC) subunits of Nuclear Factor Y (NF-Y) in wheat (Triticum aestivum) and further investigated their responses to nitrogen and phosphorus availability in wheat seedlings. Sequence mining together with gene cloning identified 18 NFYAs, 34 NFYBs, and 28 NFYCs. The expression of most NFYAs positively responded to low nitrogen and phosphorus availability. In contrast, microRNA169 negatively responded to low nitrogen and phosphorus availability and degraded NFYAs. Overexpressing TaNFYA-B1, a low-nitrogen- and low-phosphorus-inducible NFYA transcript factor on chromosome 6B, significantly increased both nitrogen and phosphorus uptake and grain yield under differing nitrogen and phosphorus supply levels in a field experiment. The increased nitrogen and phosphorus uptake may have resulted from the fact that that overexpressing TaNFYA-B1 stimulated root development and up-regulated the expression of both nitrate and phosphate transporters in roots. Our results suggest that TaNFYA-B1 plays essential roles in root development and in nitrogen and phosphorus usage in wheat. Furthermore, our results provide new knowledge and valuable gene resources that should be useful in efforts to breed crops targeting high yield with less fertilizer input. PMID:25489021

  19. Beyond the Baby Boom: The Depopulation of America.

    ERIC Educational Resources Information Center

    Morrison, Peter

    Trends toward zero population growth, more elderly drawing social security, racial polarization, changing migratory habits, and two-paycheck families will cause problems in planning educational policy. If present patterns of fertility and migration continue, society in the future may be very different from the present one. Educational policymakers…

  20. China: Awakening Giant Developing Solutions to Population Aging

    ERIC Educational Resources Information Center

    Zhang, Ning Jackie; Guo, Man; Zheng, Xiaoying

    2012-01-01

    As the world's most populous country with the largest aging population and a rapidly growing economy, China is receiving increased attention from both the Chinese government and the governments of other countries that face low fertility and aging problems. This unprecedented shift of demographic structure has repercussions for many aspects of…

  1. Variability of water quality across headwater catchments with distinct soils and hydrologic systems in central Missouri

    USDA-ARS?s Scientific Manuscript database

    Surface water and groundwater contamination by herbicides and fertilizers continues to be a major water quality problem in central Missouri. The purpose of this study was to examine spatial variability of water quality among three different headwater catchments – Goodwater Creek Experimental Watersh...

  2. Economic and phosphorus-related effects of precision feeding and forage management at a farm scale

    USDA-ARS?s Scientific Manuscript database

    A system-level redesign of farm management is needed to maintain economic viability of the farm while addressing phosphorous imbalance problems caused by many current practices. One innovative strategy, precision feed management (PFM), reduces soil-phosphorus build-up by limiting feed and fertilizer...

  3. Treatment Options for Primary Refractory/Recurrent Hodgkin Lymphoma in Children and Adolescents

    MedlinePlus

    ... back). The treatment options also depend on: The child's age and sex. The risk of long-term side effects . Most ... Physical problems that affect the following: Development of sex and reproductive organs . Fertility (ability to have children). Bone and muscle growth and development. Thyroid , heart, ...

  4. A flexible, low-cost cart for proximal sensing

    USDA-ARS?s Scientific Manuscript database

    Agricultural researchers increasingly use diverse types of electronic sensors to monitor how crops grow and respond to problems such as drought and low soil fertility. In order to take measurements on large numbers of plots in an experiment, there is a need to for simple, high-clearance vehicles tha...

  5. The Changing Balance of Births and Deaths: A Comment.

    ERIC Educational Resources Information Center

    Schultz, T. Paul

    Commenting on Kingsley Davis' paper, "Population Policy: Will Current Programs Succeed?", the author discusses the problem of rapid population growth in the low-income countries. Research strategy should focus on the family or small community to trace environmental constraints and opportunities influencing desired and achieved fertility, and…

  6. Diagnosis and Nonsurgical Management of Uterine Arteriovenous Malformation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rangarajan, R. D.; Moloney, J. C.; Anderson, H. J.

    Uterine arteriovenous malformation (AVM) is an uncommon problem and traditional treatment by hysterectomy excludes the possibility of future pregnancy. Developments in interventional techniques make transcatheter embolization of the feeding vessel(s) a therapeutic alternative, potentially preserving the patient's fertility. We present a case of successful endovascular treatment of uterine AVM.

  7. Effects of fertility on gene expression and function of the bovine endometrium

    USDA-ARS?s Scientific Manuscript database

    Infertility and subfertility are important and pervasive reproductive problems in both domestic animals and humans. The majority of embryonic loss occurs during the first three weeks of pregnancy in cattle and women due, in part, to inadequate endometrial receptivity for support of embryo implantat...

  8. A Study of the Linen and Laundry Control Procedures at the U.S. Air Force Medical Center, Wright-Patterson Air Force Base, Ohio.

    DTIC Science & Technology

    1980-08-01

    and Neck Surgery Obstetrics Infectious Diseases Internal Medicine Ocular Prosthesis Surgery Oral Surgery Orthopedic Surgery Maxillofacial Surgery...standpoint of an ability to adequately and correctly function and was a fertile area for review and examination. Statement of the Problem The problem was...was not favorable with shared base use laundry services, it should not be considered as a vote of "no-confidence" for its use industry wide. A review

  9. Antral follicle count in normal (fertility-proven) and infertile Indian women.

    PubMed

    Agarwal, Arjit; Verma, Ashish; Agarwal, Shubhra; Shukla, Ram Chandra; Jain, Madhu; Srivastava, Arvind

    2014-07-01

    Antral follicle count (AFC) has been labeled as the most accurate biomarker to assess female fecundity. Unfortunately, no baseline Indian data exists, and we continue using surrogate values from the Western literature (inferred from studies on women, grossly different than Indian women in morphology and genetic makeup). (1) To establish the role of AFC as a function of ovarian reserve in fertility-proven and in subfertile Indian women. (2) To establish baseline cut-off AFC values for Indian women. Prospective observational case-control study. Thirty patients undergoing workup for infertility were included and compared to equal number of controls (women with proven fertility). The basal ovarian volume and AFC were measured by endovaginal. USG the relevant clinical data and hormonal assays were charted for every patient. SPSS platform was used to perform the Student's t-test and Mann-Whitney U-test for intergroup comparisons. Correlations were determined by Pearson's ranked correlation coefficient. Regression analysis revealed the highest correlation of AFC and age in fertile and infertile patients with difference in mean AFC of both the groups. Comparison of the data recorded for cases and controls showed no significant difference in the mean ovarian volume. AFC has the closest association with chronological age in normal and infertile Indian women. The same is lower in infertile women than in matched controls. Baseline and cut-off values in Indian women are lower than that mentioned in the Western literature.

  10. Facilitating and supporting HIV+ parenthood: Lessons for developing the advocate role of voluntary HIV support services workers.

    PubMed

    Cane, Tam Pheona Chipawe

    2018-06-01

    Increasingly as people living with HIV (PLWHIV) aim to become parents, they engage with HIV voluntary services for support through either fertility or adoption services. Yet, little is known about the role of HIV support services workers in facilitating access to fertility treatment or child adoption. The purpose of this study was to explore the role of HIV support workers based in HIV voluntary organisations who have a key role helping PLWHIV in navigating relevant fertility and adoption processes. This was an exploratory qualitative study which involved interviewing six HIV support workers, from across the UK. Interviews were conducted using face to face interviews, recorded and transcribed. Findings revealed that HIV services support workers provide practical support in advocating service provision, and emotional and social support along the journey. They also face challenges in their role from health care professionals including information sharing and gatekeeping. The role of HIV support workers is important in facilitating access to resources and complex systems. HIV support workers should be recognised and as they are often a trusted professional to address stigma, discrimination and barriers to services. The study contributes to research seeking to understand the emerging needs and support requirements for people living with HIV seeking fertility and adoption. Further work in this area is warranted. Copyright © 2018 Elsevier B.V. All rights reserved.

  11. Characterizing partial AZFc deletions of the Y chromosome with amplicon-specific sequence markers

    PubMed Central

    Navarro-Costa, Paulo; Pereira, Luísa; Alves, Cíntia; Gusmão, Leonor; Proença, Carmen; Marques-Vidal, Pedro; Rocha, Tiago; Correia, Sónia C; Jorge, Sónia; Neves, António; Soares, Ana P; Nunes, Joaquim; Calhaz-Jorge, Carlos; Amorim, António; Plancha, Carlos E; Gonçalves, João

    2007-01-01

    Background The AZFc region of the human Y chromosome is a highly recombinogenic locus containing multi-copy male fertility genes located in repeated DNA blocks (amplicons). These AZFc gene families exhibit slight sequence variations between copies which are considered to have functional relevance. Yet, partial AZFc deletions yield phenotypes ranging from normospermia to azoospermia, thwarting definite conclusions on their real impact on fertility. Results The amplicon content of partial AZFc deletion products was characterized with novel amplicon-specific sequence markers. Data indicate that partial AZFc deletions are a male infertility risk [odds ratio: 5.6 (95% CI: 1.6–30.1)] and although high diversity of partial deletion products and sequence conversion profiles were recorded, the AZFc marker profiles detected in fertile men were also observed in infertile men. Additionally, the assessment of rearrangement recurrence by Y-lineage analysis indicated that while partial AZFc deletions occurred in highly diverse samples, haplotype diversity was minimal in fertile men sharing identical marker profiles. Conclusion Although partial AZFc deletion products are highly heterogeneous in terms of amplicon content, this plasticity is not sufficient to account for the observed phenotypical variance. The lack of causative association between the deletion of specific gene copies and infertility suggests that AZFc gene content might be part of a multifactorial network, with Y-lineage evolution emerging as a possible phenotype modulator. PMID:17903263

  12. [Assessment of progesterone levels on the day of the hCG administration as a predictor of success of antagonist stimulation protocols for IVF].

    PubMed

    Kably-Ambe, Alberta; Roque-Sánchez, Armando Miguel; Soriano-Ortega, Karla Patricia; Carballo-Mondragón, Esperanza; Durán-Monterrosas, Leonor

    2015-03-01

    There are reports of deleterious effect when progesterone concentration is high during the follicular phase in cycles of in vitro fertilization. In our environment has not carried out a study to evaluate the pregnancy rate compared with progesterone concentration on the day of application of hCG. To evaluate the pregnancy rate and outcome of in vitro fertilization cycle according to serum progesterone concentration on the day of application of hCG. A retrospective, observational, cross-sectional study of 486 cycles of in vitro fertilization was done in the Centro Mexicano de Fertilidad of CEPAM (Hospital Angeles de las Lomas) from January 2009 to February 2014. We included all cases where it was used a stimulation protocol GnRH antagonist flexible scheme. When levels of progesterone are high, those of estradiol are also high and the number of retrieved oocytes and oocyte quality are lower. There was no difference in the percentage of fertilization, but at higher concentration of progesterone lower percentage of embryonic segmentation. Difference was recorded in the pregnancy rate only when progesterone concentration on the day of hCG application was > 4 ng/mL. Pregnancy rate decreases when the concentration of progesterone on the day of hCG application is ≥ 4 ng/mL.

  13. The stressors and vulnerabilities of young single childless women with breast cancer: a qualitative study.

    PubMed

    Corney, Roslyn; Puthussery, Shuby; Swinglehurst, Jane

    2014-02-01

    Marital or partnership status is seldom investigated as a primary contributing factor to women's wellbeing after a diagnosis of breast cancer. It has been suggested, however, that single childless women with breast cancer may face unique stressors. This paper explores the stressors and vulnerabilities of young single childless women with a first episode of breast cancer. A qualitative descriptive method was used. As part of a larger study examining fertility concerns of young childless women with first episode of breast cancer, in-depth semi-structured interviews were conducted with 10 single women. Recorded interviews were analysed using the framework approach. Findings cover three main themes: partnership worries; fertility concerns; and views about emotional and practical support received. Partnership worries included concerns about having to undergo treatment without a partner to support them; the fear of rejection by potential partners; and feelings about the precious time lost in diagnosis and treatment. Fertility concerns included dilemmas about having children and feelings about the options of pursuing Assisted Reproductive Techniques. Views about the emotional and practical support received included the overall support received as well as perceptions about the attitudes of health professionals towards fertility issues. Findings indicate that single childless women with breast cancer face additional vulnerabilities and may benefit from tailored support from health care professionals and interventions specifically targeted at them. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. Cyanobacteria: A Precious Bio-resource in Agriculture, Ecosystem, and Environmental Sustainability.

    PubMed

    Singh, Jay Shankar; Kumar, Arun; Rai, Amar N; Singh, Devendra P

    2016-01-01

    Keeping in view, the challenges concerning agro-ecosystem and environment, the recent developments in biotechnology offers a more reliable approach to address the food security for future generations and also resolve the complex environmental problems. Several unique features of cyanobacteria such as oxygenic photosynthesis, high biomass yield, growth on non-arable lands and a wide variety of water sources (contaminated and polluted waters), generation of useful by-products and bio-fuels, enhancing the soil fertility and reducing green house gas emissions, have collectively offered these bio-agents as the precious bio-resource for sustainable development. Cyanobacterial biomass is the effective bio-fertilizer source to improve soil physico-chemical characteristics such as water-holding capacity and mineral nutrient status of the degraded lands. The unique characteristics of cyanobacteria include their ubiquity presence, short generation time and capability to fix the atmospheric N2. Similar to other prokaryotic bacteria, the cyanobacteria are increasingly applied as bio-inoculants for improving soil fertility and environmental quality. Genetically engineered cyanobacteria have been devised with the novel genes for the production of a number of bio-fuels such as bio-diesel, bio-hydrogen, bio-methane, synga, and therefore, open new avenues for the generation of bio-fuels in the economically sustainable manner. This review is an effort to enlist the valuable information about the qualities of cyanobacteria and their potential role in solving the agricultural and environmental problems for the future welfare of the planet.

  15. Human population reduction is not a quick fix for environmental problems.

    PubMed

    Bradshaw, Corey J A; Brook, Barry W

    2014-11-18

    The inexorable demographic momentum of the global human population is rapidly eroding Earth's life-support system. There are consequently more frequent calls to address environmental problems by advocating further reductions in human fertility. To examine how quickly this could lead to a smaller human population, we used scenario-based matrix modeling to project the global population to the year 2100. Assuming a continuation of current trends in mortality reduction, even a rapid transition to a worldwide one-child policy leads to a population similar to today's by 2100. Even a catastrophic mass mortality event of 2 billion deaths over a hypothetical 5-y window in the mid-21(st) century would still yield around 8.5 billion people by 2100. In the absence of catastrophe or large fertility reductions (to fewer than two children per female worldwide), the greatest threats to ecosystems--as measured by regional projections within the 35 global Biodiversity Hotspots--indicate that Africa and South Asia will experience the greatest human pressures on future ecosystems. Humanity's large demographic momentum means that there are no easy policy levers to change the size of the human population substantially over coming decades, short of extreme and rapid reductions in female fertility; it will take centuries, and the long-term target remains unclear. However, some reduction could be achieved by midcentury and lead to hundreds of millions fewer people to feed. More immediate results for sustainability would emerge from policies and technologies that reverse rising consumption of natural resources.

  16. 'Mama and papa nothing': living with infertility among an urban population in Kigali, Rwanda.

    PubMed

    Dhont, N; van de Wijgert, J; Coene, G; Gasarabwe, A; Temmerman, M

    2011-03-01

    Not being able to procreate has severe social and economic repercussions in resource-poor countries. The purpose of this research was to explore the consequences of female and/or male factor infertility for men and women in Rwanda. Both quantitative and qualitative methods were used. Couples presenting with female and/or male factor infertility problems at the infertility clinic of the Kigali University Teaching Hospital (n = 312), and fertile controls who recently delivered (n = 312), were surveyed about domestic violence, current and past relationships and sexual functioning. In addition, five focus group discussions were held with a subsample of survey participants, who were either patients diagnosed with female- or male-factor fertility or their partners. Domestic violence, union dissolutions and sexual dysfunction were reported more frequently in the survey by infertile than fertile couples. The psycho-social consequences suffered by infertile couples in Rwanda are severe and similar to those reported in other resource-poor countries. Although women carry the largest burden of suffering, the negative repercussions of infertility for men, especially at the level of the community, are considerable. Whether the infertility was caused by a female factor or male factor was an important determinant for the type of psycho-social consequences suffered. In Rwanda, as in other resource-poor countries, infertility causes severe suffering. There is an urgent need to recognize infertility as a serious reproductive health problem and to put infertility care on the public health agenda.

  17. Cyanobacteria: A Precious Bio-resource in Agriculture, Ecosystem, and Environmental Sustainability

    PubMed Central

    Singh, Jay Shankar; Kumar, Arun; Rai, Amar N.; Singh, Devendra P.

    2016-01-01

    Keeping in view, the challenges concerning agro-ecosystem and environment, the recent developments in biotechnology offers a more reliable approach to address the food security for future generations and also resolve the complex environmental problems. Several unique features of cyanobacteria such as oxygenic photosynthesis, high biomass yield, growth on non-arable lands and a wide variety of water sources (contaminated and polluted waters), generation of useful by-products and bio-fuels, enhancing the soil fertility and reducing green house gas emissions, have collectively offered these bio-agents as the precious bio-resource for sustainable development. Cyanobacterial biomass is the effective bio-fertilizer source to improve soil physico-chemical characteristics such as water-holding capacity and mineral nutrient status of the degraded lands. The unique characteristics of cyanobacteria include their ubiquity presence, short generation time and capability to fix the atmospheric N2. Similar to other prokaryotic bacteria, the cyanobacteria are increasingly applied as bio-inoculants for improving soil fertility and environmental quality. Genetically engineered cyanobacteria have been devised with the novel genes for the production of a number of bio-fuels such as bio-diesel, bio-hydrogen, bio-methane, synga, and therefore, open new avenues for the generation of bio-fuels in the economically sustainable manner. This review is an effort to enlist the valuable information about the qualities of cyanobacteria and their potential role in solving the agricultural and environmental problems for the future welfare of the planet. PMID:27148218

  18. Cystic echinococcosis in cattle slaughtered at Gondar Elfora export Abattoir, northwest Ethiopia.

    PubMed

    Abebe, Abebaw; Beyene, Desta; Kumsa, Bersissa

    2014-12-01

    A cross sectional and retrospective studies were conducted from November 2010 to April 2011 to determine the prevalence and characteristics of hydatid cysts in cattle slaughtered at Gondar Elfora Abattoir in northern Ethiopia. Out of the 308 cattle examined for the presence of hydatid cysts, 63 (20.5 %) of them were found harboring hydatid cysts in one or more of their internal organs. Results of the study showed higher (P < 0.05) prevalence of cystic echinococcosis in adult (22.4 %; 49/219) than in young (15.7 %; 14/89) cattle. Lowest prevalence of hydatid cysts was observed in cattle from Debark (7.7 %; 2/26) whereas highest prevalence of cystic echinococcosis was recorded in cattle from Fogera (28.2 %; 11/39). The lungs (69.3 %; 61/88) were the most affected organs followed by the livers (28.4 %; 25/88). A total of 230 hydatid cysts from different internal organs of 63 infected cattle were differentiated into 60.4 % calcified, 30 % fertile and 9.6 % sterile cysts. Likewise, a total of 13 % (30/230) small, 15.6 % (36/230) medium, and 10.9 % (25/230) large hydatid cysts were recorded. Lung harbored the highest overall count (76.9 %; 177/230) and greatest proportion of large size cysts (13.5 %; 103/177) than all the other organs. Liver harbored the highest proportion of calcified cysts (68 %; 34/50). An overall proportion of 30 % (69/230) fertile cysts were recorded. The greatest proportion of fertile cysts (33.3 %; 59/177) was recorded in lungs followed by the livers (20 %; 10/50). A retrospective data of 5 years (2004/5-2009/10) revealed an overall prevalence of 30.4 % (9,106/29,951) and highest overall prevalence of 65.5 % hydatid cysts in the lungs followed by livers (33.5 %) and least in spleen (0.04 %). In conclusion the findings reported herein show that cystic echinococcosis is widespread in cattle slaughtered in Gondar export Abattoir and suggests that the lung is the most important source of hydatid cysts for definitive hosts in the area.

  19. Relationship between Porcine Sperm Motility and Sperm Enzymatic Activity using Paper-based Devices

    NASA Astrophysics Data System (ADS)

    Matsuura, Koji; Huang, Han-Wei; Chen, Ming-Cheng; Chen, Yu; Cheng, Chao-Min

    2017-04-01

    Mammalian sperm motility has traditionally been analyzed to determine fertility using computer-assisted semen analysis (CASA) systems. To develop low-cost and robust male fertility diagnostics, we created a paper-based MTT assay and used it to estimate motile sperm concentration. When porcine sperm motility was inhibited using sperm enzyme inhibitors for sperm enzymes related to mitochondrial activity and glycolysis, we simultaneously recorded sperm motility and enzymatic reactivity using a portable motility analysis system (iSperm) and a paper-based MTT assay, respectively. When using our paper-based MTT-assay, we calculated the area mean value signal intensity (AMV) to evaluate enzymatic reactivity. Both sperm motility and AMV decreased following treatment with iodoacetamide (IODO) and 3-bromopyruvic acid (3BP), both of which are inhibitors of glycolytic enzymes including glyceraldehyde-3-phosphate dehydrogenase (GAPDH). We found a correlation between recorded motility using iSperm and AMV from our paper-based assay (P < 0.05), suggesting that a sperm-related enzymatic reaction is involved in sperm motility. Under this protocol, MTT reduction was coupled with catalysis of GAPDH and was promoted by electron transfer from NADH. Based on this inhibitor study, sperm motility can be estimated using our paper-based MTT-assay.

  20. The effect of cigarette smoke on fertilization and pre-implantation development: assessment using animal models, clinical data, and stem cells.

    PubMed

    Talbot, Prue; Lin, Sabrina

    2011-01-01

    Numerous studies have repeatedly shown that women who smoke experience problems establishing and maintaining pregnancies, and recent work has further demonstrated that the in utero effects of smoke may not be manifested until months or even years after birth. The purpose of this review is to examine the recent literature dealing with the effects of cigarette smoke on the earliest stages of human prenatal development. Studies in this area have included the use of animal models, patients undergoing in vitro fertilization, and embryonic stem cell models. Events leading to fertilization, such as cumulus expansion, hyperactivation of sperm motility, and oocyte pick-up by the oviduct are all impaired by smoke exposure in animal models. Steps crucial to fertilization such as the acrosome reaction and sperm binding to the zona pellucida are likewise inhibited by cigarette smoke. Preimplantation embryos and stem cells that model embryos show a number of adverse responses to smoke exposure, including poor adhesion to extracellular matrices, diminished survival and proliferation, and increased apoptosis. The current literature demonstrates that the earliest stages of prenatal development are sensitive to smoke exposure and indicates that pregnant women should be advised not to smoke during this time.

  1. Nitrogen fluxes at the root-soil interface show a mismatch of nitrogen fertilizer supply and sugarcane root uptake capacity

    PubMed Central

    Brackin, Richard; Näsholm, Torgny; Robinson, Nicole; Guillou, Stéphane; Vinall, Kerry; Lakshmanan, Prakash; Schmidt, Susanne; Inselsbacher, Erich

    2015-01-01

    Globally only ≈50% of applied nitrogen (N) fertilizer is captured by crops, and the remainder can cause pollution via runoff and gaseous emissions. Synchronizing soil N supply and crop demand will address this problem, however current soil analysis methods provide little insight into delivery and acquisition of N forms by roots. We used microdialysis, a novel technique for in situ quantification of soil nutrient fluxes, to measure N fluxes in sugarcane cropping soils receiving different fertilizer regimes, and compare these with N uptake capacities of sugarcane roots. We show that in fertilized sugarcane soils, fluxes of inorganic N exceed the uptake capacities of sugarcane roots by several orders of magnitude. Contrary, fluxes of organic N closely matched roots’ uptake capacity. These results indicate root uptake capacity constrains plant acquisition of inorganic N. This mismatch between soil N supply and root N uptake capacity is a likely key driver for low N efficiency in the studied crop system. Our results also suggest that (i) the relative contribution of inorganic N for plant nutrition may be overestimated when relying on soil extracts as indicators for root-available N, and (ii) organic N may contribute more to crop N supply than is currently assumed. PMID:26496834

  2. Molecular Modeling and docking of Wheat Hydroquinone Glucosyl transferase by using Hydroquinone, Phenyl phosphorodiamate and n-(n butyl) Phosphorothiocic Triamide as Inhibitors

    PubMed Central

    Huma, Tayyaba; Maryam, Arooma; qamar, Tahir ul

    2014-01-01

    In agriculture high urease activity during urea fertilization causes substantial environmental and economical problems by releasing abnormally large amount of ammonia into the atmosphere which leads to plant damage as well as ammonia toxicity. All over the world, urea is the most widely applied nitrogen fertilizer. Due to the action of enzyme urease; urea nitrogen is lost as volatile ammonia. For efficient use of nitrogen fertilizer, urease inhibitor along with the urea fertilizer is one of the best promising strategies. Urease inhibitors also provide an insight in understanding the mechanism of enzyme catalyzed reaction, the role of various amino acids in catalytic activity present at the active site of enzyme and the importance of nickel to this metallo enzyme. By keeping it in view, the present study was designed to dock three urease inhibitors namely Hydroquinone (HQ), Phenyl Phosphorodiamate (PPD) and N-(n-butyl) Phosphorothiocic triamide (NBPT) against Hydroquinone glucosyltransferase using molecular docking approach. The 3D structure of Hydroquinone glucosyltransferase was predicted using homology modeling approach and quality of the structure was assured using Ramachandran plot. This study revealed important interactions among the urease inhibitors and Hydroquinone glucosyltransferase. Thus, it can be inferred that these inhibitors may serve as future anti toxic constituent against plant toxins. PMID:24748751

  3. Molecular Modeling and docking of Wheat Hydroquinone Glucosyl transferase by using Hydroquinone, Phenyl phosphorodiamate and n-(n butyl) Phosphorothiocic Triamide as Inhibitors.

    PubMed

    Huma, Tayyaba; Maryam, Arooma; Qamar, Tahir Ul

    2014-01-01

    In agriculture high urease activity during urea fertilization causes substantial environmental and economical problems by releasing abnormally large amount of ammonia into the atmosphere which leads to plant damage as well as ammonia toxicity. All over the world, urea is the most widely applied nitrogen fertilizer. Due to the action of enzyme urease; urea nitrogen is lost as volatile ammonia. For efficient use of nitrogen fertilizer, urease inhibitor along with the urea fertilizer is one of the best promising strategies. Urease inhibitors also provide an insight in understanding the mechanism of enzyme catalyzed reaction, the role of various amino acids in catalytic activity present at the active site of enzyme and the importance of nickel to this metallo enzyme. By keeping it in view, the present study was designed to dock three urease inhibitors namely Hydroquinone (HQ), Phenyl Phosphorodiamate (PPD) and N-(n-butyl) Phosphorothiocic triamide (NBPT) against Hydroquinone glucosyltransferase using molecular docking approach. The 3D structure of Hydroquinone glucosyltransferase was predicted using homology modeling approach and quality of the structure was assured using Ramachandran plot. This study revealed important interactions among the urease inhibitors and Hydroquinone glucosyltransferase. Thus, it can be inferred that these inhibitors may serve as future anti toxic constituent against plant toxins.

  4. Extreme weather conditions reduce the CO2 fertilization effect in temperate C3 grasslands

    NASA Astrophysics Data System (ADS)

    Obermeier, Wolfgang; Lehnert, Lukas; Kammann, Claudia; Müller, Christoph; Grünhage, Ludger; Luterbacher, Jürg; Erbs, Martin; Yuan, Naiming; Bendix, Jörg

    2016-04-01

    The increase in atmospheric greenhouse gas concentrations from anthropogenic activities is the major driver of global climate change. The rising atmospheric carbon dioxide (CO2) concentrations may stimulate plant photosynthesis and, thus, cause a net sink effect in the global carbon cycle. As a consequence of an enhanced photosynthesis, an increase in the net primary productivity (NPP) of C3 plants (termed CO2 fertilization) is widely assumed. This process is associated with a reduced stomatal conductance of leaves as the carbon demand of photosynthesis is met earlier. This causes a higher water-use efficiency and, hence, may reduce water stress in plants exposed to elevated CO2 concentrations ([eCO2]). However, the magnitude and persistence of the CO2 fertilization effect under a future climate including more frequent weather extremes are controversial. To test the CO2 fertilization effect for Central European grasslands, a data set comprising 16 years of biomass samples and environmental variables such as local weather and soil conditions was analysed by means of a novel approach. The data set was recorded on a "Free Air Carbon dioxide Enrichment" (FACE) experimental site which allows to quantify the CO2 fertilization effect under naturally occurring climate variations. The results indicate that the CO2 fertilization effect on the aboveground biomass is strongest under local average environmental conditions. Such intermediate regimes were defined by the mean +/- 1 standard deviation of the long-term average in the respective variable three months before harvest. The observed CO2 fertilization effect was reduced or vanished under drier, wetter and hotter conditions when the respective variable exceeded the bounds of the intermediate regimes. Comparable conditions, characterized by a higher frequency of more extreme weather conditions, are predicted for the future by climate projections. Consequently, biogeochemical models may overestimate the future NPP sink capacity of temperate C3 grasslands. Because temperate grasslands represent an important part of the Earth's terrestrial surface and therefore the global carbon cycle, atmospheric CO2 concentrations [CO2] might increase faster than currently expected.

  5. Study protocol for Young & Strong: a cluster randomized design to increase attention to unique issues faced by young women with newly diagnosed breast cancer.

    PubMed

    Greaney, Mary L; Sprunck-Harrild, Kim; Ruddy, Kathryn J; Ligibel, Jennifer; Barry, William T; Baker, Emily; Meyer, Meghan; Emmons, Karen M; Partridge, Ann H

    2015-01-31

    Each year, approximately 11% of women diagnosed with breast cancer in the United States are 45 years of age or younger. These women have concerns specific to or accentuated by their age, including fertility-related concerns, and have higher rates of psychosocial distress than women diagnosed at older ages. Current guidelines recommend that fertility risks be considered early in all treatment plans; however, the extant research indicates that attention to fertility by the healthcare team is limited. Importantly, attention to fertility may be a proxy for whether or not other important issues warranting attention in younger women with breast cancer are addressed, including genetic risks, psychosocial distress, sexual functioning, and body image concerns. The Young & Strong study tests the efficacy of an intervention designed for young women recently diagnosed with breast cancer and their oncologists with the intention to: 1) increase attention to fertility as an important surrogate for other issues facing young women, 2) educate and support young women and their providers, and 3) reduce psychosocial distress among young women with breast cancer. The study employs a cluster randomized design including 14 academic institutions and 40 community sites across the U.S. assigned to either the study intervention arm or contact-time comparison intervention arm. Academic institutions enroll up to 15 patients per site while community sites enroll up to 10 patients. Patient eligibility requirements include: an initial diagnosis of stage I-III invasive breast cancer within three months prior, without a known recurrence or metastatic breast cancer; 18-45 years of age at diagnosis; ability to read and write in English. The primary outcome is oncologists' attention to fertility concerns as determined by medical record review. Secondary outcomes include differences in patient satisfaction with care and psychosocial distress between the two study arms. Study findings will provide valuable insight into how to increase attention to fertility and other issues specific to young women with breast cancer and how to improve doctor-patient communication around these issues, which may promote better quality of care for this population. NCT01647607. Registered July 19, 2012.

  6. Multiple-trait estimates of genetic parameters for metabolic disease traits, fertility disorders, and their predictors in Canadian Holsteins.

    PubMed

    Jamrozik, J; Koeck, A; Kistemaker, G J; Miglior, F

    2016-03-01

    Producer-recorded health data for metabolic disease traits and fertility disorders on 35,575 Canadian Holstein cows were jointly analyzed with selected indicator traits. Metabolic diseases included clinical ketosis (KET) and displaced abomasum (DA); fertility disorders were metritis (MET) and retained placenta (RP); and disease indicators were fat-to-protein ratio, milk β-hydroxybutyrate, and body condition score (BCS) in the first lactation. Traits in first and later (up to fifth) lactations were treated as correlated in the multiple-trait (13 traits in total) animal linear model. Bayesian methods with Gibbs sampling were implemented for the analysis. Estimates of heritability for disease incidence were low, up to 0.06 for DA in first lactation. Among disease traits, the environmental herd-year variance constituted 4% of the total variance for KET and less for other traits. First- and later-lactation disease traits were genetically correlated (from 0.66 to 0.72) across all traits, indicating different genetic backgrounds for first and later lactations. Genetic correlations between KET and DA were relatively strong and positive (up to 0.79) in both first- and later-lactation cows. Genetic correlations between fertility disorders were slightly lower. Metritis was strongly genetically correlated with both metabolic disease traits in the first lactation only. All other genetic correlations between metabolic and fertility diseases were statistically nonsignificant. First-lactation KET and MET were strongly positively correlated with later-lactation performance for these traits due to the environmental herd-year effect. Indicator traits were moderately genetically correlated (from 0.30 to 0.63 in absolute values) with both metabolic disease traits in the first lactation. Smaller and mostly nonsignificant genetic correlations were among indicators and metabolic diseases in later lactations. The only significant genetic correlations between indicators and fertility disorders were those between BCS and MET in both first and later lactations. Results indicated a limited value of a joint genetic evaluation model for metabolic disease traits and fertility disorders in Canadian Holsteins. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  7. International investigation into the relationship between social expenditure for family and total fertility rate.

    PubMed

    Motoki, Airi; Shinohara, Ryoji; Yamagata, Zentaro

    2016-01-01

    Purpose Declining birth rates are an important social issue worldwide, and allocating resources to benefits for child-rearing households is a necessary countermeasure. In this study, we investigate and compare the relationship between child-related social security costs and total fertility rate internationally.Method In 2011, the ratios of family- and elderly-related social spending to gross domestic product (GDP) were recorded in 34 Organisation for Economic Co-operation and Development (OECD) member countries. The former was designated as the percentage allocated to members of the population between the ages of 0 and 14 (young population ratio), and the latter was designated as the percentage allocated to members of the population over the age of 65 (elderly population ratio). We compared these two factors for every country and performed correlation and partial correlation analyses of total fertility rates and family-related social spending to GDP adjusted by population proportion to examine the relationship between the two.Results The comparison of the youth and elderly populations' spending ratios in the total social spending to GDP ratio revealed that OECD countries had an average family-related social spending ratio of 0.13 and an average elderly-related social spending ratio of 0.47. Comparatively, Japan has a family-related social spending ratio of 0.10 and an elderly-related social spending ratio of 0.45. In the correlation analysis for total fertility rates and family-related social spending to GDP ratio, the benefits-in-kind to GDP ratio and total fertility rates indicated a trend toward correlation (r=0.32, P=0.06). In addition, the results for the partial correlation between family-related social spending to GDP ratio and total fertility rates showed a significant correlation between the two. When divided into cash benefits and benefits-in-kind, the partial correlation analysis of the GDP ratios and total fertility rates revealed a significant correlation (r=0.51, P<0.01). Benefits-in-kind (r=0.45, P<0.01) had a stronger correlation than did cash benefits (r=0.39, P=0.03).Conclusion In an international comparison accounting for economic standards, the social security cost of children and child-rearing families in Japan was low. Further, in terms of social security spending, increasing benefits-in-kind, such as improving childcare services or preschool education, is one factor that improves the total fertility rate.

  8. Fertility in adult women with classic galactosemia and primary ovarian insufficiency.

    PubMed

    van Erven, Britt; Berry, Gerard T; Cassiman, David; Connolly, Geraldine; Forga, Maria; Gautschi, Matthias; Gubbels, Cynthia S; Hollak, Carla E M; Janssen, Mirian C; Knerr, Ina; Labrune, Philippe; Langendonk, Janneke G; Õunap, Katrin; Thijs, Abel; Vos, Rein; Wortmann, Saskia B; Rubio-Gozalbo, M Estela

    2017-07-01

    To study pregnancy chance in adult women with classic galactosemia and primary ovarian insufficiency. Despite dietary treatment, >90% of women with classic galactosemia develop primary ovarian insufficiency, resulting in impaired fertility. For many years, chance of spontaneous conception has not been considered, leading to counseling for infertility. But an increasing number of reports on pregnancies in this group questions whether current counseling approaches are correct. Multicenter retrospective observational study. Metabolic centers. Adult women (aged >18 y) with confirmed classic galactosemia and primary ovarian insufficiency were included. Participants and medical records were consulted to obtain study data in a standardized manner with the use of a questionnaire. Conception opportunities, time to pregnancy, pregnancy outcome, hormone replacement therapy use, fertility counseling, and the participants' vision of fertility were evaluated. Potential predictive factors for increased pregnancy chance were explored. Eighty-five women with classic galactosemia and primary ovarian insufficiency participated. Twenty-one women actively attempted to conceive or did not take adequate contraceptive precautions. Of these 21 women, nine became pregnant spontaneously (42.9%). This was higher than reported in primary ovarian insufficiency due to other causes (5%-10%). After a period of 12 months, a cumulative proportion of 27.8% of couples had conceived, which increased to 48.4% after 24 months and 61.3% after 27 months. Predictive factors could not be identified. A considerable miscarriage rate of 30% was observed (6 of 20 pregnancies). Although a substantial proportion of women expressed a child-wish (n = 28/53; 52.8%), the vast majority of participants (n = 43/57; 75.4%) considered conceiving to be highly unlikely, owing to negative counseling in the past. The pregnancy rate in women with classic galactosemia and primary ovarian insufficiency was higher than for women with primary ovarian insufficiency of any cause. This shifting paradigm carries significant implications for fertility counseling and potential application of fertility preservation techniques. Copyright © 2017 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  9. The Rengen Grassland experiment: bryophytes biomass and element concentrations after 65 years of fertilizer application.

    PubMed

    Hejcman, Michal; Száková, Jirina; Schellberg, Jürgen; Srek, Petr; Tlustos, Pavel; Balík, Jirí

    2010-07-01

    The Rengen Grassland Experiment in Germany, established in 1941, consists of the following fertilizer treatments applied under a two cut management: control, Ca, CaN, CaNP, CaNP-KCl, and CaNP-K(2)SO(4). The aim of this study was (1) to identify effects of fertilizer application on biomass and species composition of bryophytes and (2) to investigate the impact of fertilizer application on macro- (N, P, K, Ca, Mg), micro- (Cu, Fe, Mn, Zn), and toxic (As, Cd, Cr, Pb, Ni) element concentrations in bryophyte biomass. In June 2006, Rhytidiadelphus squarrosus was the only bryophyte species recorded in the control. In treatment Ca, R. squarrosus was the dominant bryophyte species whereas Brachythecium rutabulum occurred sporadically only in a single plot of that treatment. The latter was the only bryophyte species collected in CaN, CaNP, CaNP-KCl, and CaNP-K(2)SO(4) treatments. Dry matter accumulation of bryophytes was highest in the control (180 g m(-2)) followed by Ca (46 g m(-2)), CaNP (25 g m(-2)), CaNP-KCl (15 g m(-2)), CaNP-K(2)SO(4) (9 g m(-2)), and CaN (2 g m(-2)) treatments. A negative correlation between biomass production of bryophytes and dry matter production of vascular plants was revealed up to a threshold value of 400 g m(-2). Above this limit, biomass production of bryophytes remained obviously unaffected by further increase in biomass production of vascular plants. A significant effect of treatment on As, Cd, Cr, Fe, Mn, Ni, Pb, P, Ca, Mg, K, and N concentrations was revealed. Concentrations of these elements were a function of amount of elements supplied with fertilizers. Bryophytes seem to be promising bio-indicators not only for airborne deposition of toxic element but also for fertilizer introduced as well.

  10. African land degradation in a world of global atmospheric change: fertilization conceals degradation?

    NASA Astrophysics Data System (ADS)

    Le, Lulseged Tamene, Paul L. G. Vlek, Quang Bao

    2009-04-01

    Land degradation is one of the most widespread environmental problems worldwide. The sub-Saharan Africa (SSA) is one of the most seriously affected regions with huge implications on food security and economic development. To plan plausible management measures, understanding the magnitude of the problem and identification of hotspot areas are necessary. Analysis of remote sensing and climate data observed from space for the period 1982 - 2003 showed significant improvement in vegetation productivity across 30% of SSA with decline on 5% of the subcontinent. Global change in atmospheric chemistry is likely responsible for the observed increasing trend in vegetation productivity. Such widespread greening observed from space could mask anthropogenic land degradation processes such as land conversion, selective logging, and soil nutrient mining. To assess this possible masking effect, a re-analysis of the vegetation productivity dynamics, taking into account atmospheric fertilization, was conducted. This was performed by analyzing the long-term trend in vegetation productivity of pristine lands (areas with minimum human- and climate- related impacts) identified across different biomes in SSA. The baseline slope values of biomass accrual calculated for those pristine lands were estimated and used to re-calculate the long-term trend of green biomass with and without the impact of atmospheric fertilization. This ultimately enabled to delineate the areas that would have experienced significant loss in vegetation productivity had the atmospheric chemistry not changed. The result suggests that seven times more than the area of actual productivity decline in SSA is affected by land degradation processes that are concealed by atmospheric fertilization. With this rate of surreptitious loss of vital land attributes and with the current rate of population growth (3%), the SSA subcontinent may soon lack the land resources necessary to foster economic development. Spatially distributed field data are, however, required to ascertain the validity of the results presented.

  11. Glutathione S-transferase activity in follicular fluid from women undergoing ovarian stimulation: role in maturation.

    PubMed

    Meijide, Susana; Hernández, M Luisa; Navarro, Rosaura; Larreategui, Zaloa; Ferrando, Marcos; Ruiz-Sanz, José Ignacio; Ruiz-Larrea, M Begoña

    2014-10-01

    Female infertility involves an emotional impact for the woman, often leading to a state of anxiety and low self-esteem. The assisted reproduction techniques (ART) are used to overcome the problem of infertility. In a first step of the in vitro fertilization therapy women are subjected to an ovarian stimulation protocol to obtain mature oocytes, which will result in competent oocytes necessary for fertilization to occur. Ovarian stimulation, however, subjects the women to a high physical and psychological stress, thus being essential to improve ART and to find biomarkers of dysfunction and fertility. GSH is an important antioxidant, and is also used in detoxification reactions, catalysed by glutathione S-transferases (GST). In the present work, we have investigated the involvement of GST in follicular maturation. Patients with fertility problems and oocyte donors were recruited for the study. From each woman follicles at two stages of maturation were extracted at the preovulatory stage. Follicular fluid was separated from the oocyte by centrifugation and used as the enzyme source. GST activity was determined based on its conjugation with 3,4-dichloronitrobenzene and the assay was adapted to a 96-well microplate reader. The absorbance was represented against the incubation time and the curves were adjusted to linearity (R(2)>0.990). Results showed that in both donors and patients GST activity was significantly lower in mature oocytes compared to small ones. These results suggest that GST may play a role in the follicle maturation by detoxifying xenobiotics, thus contributing to the normal development of the oocyte. Supported by FIS/FEDER (PI11/02559), Gobierno Vasco (Dep. Educación, Universiades e Investigación, IT687-13), and UPV/EHU (CLUMBER UFI11/20 and PES13/58). The work was approved by the Ethics Committee of the UPV/EHU (CEISH/96/2011/RUIZLARREA), and performed according to the UPV/EHU and IVI-Bilbao agreement (Ref. 2012/01). Copyright © 2014. Published by Elsevier Inc.

  12. Genetic relationship of body energy and blood metabolites with reproduction in holstein cows.

    PubMed

    Oikonomou, G; Arsenos, G; Valergakis, G E; Tsiaras, A; Zygoyiannis, D; Banos, G

    2008-11-01

    Body condition score (BCS), energy content (EC), cumulative effective energy balance (CEEB), and blood serum concentrations of glucose, beta-hydroxybutyrate (BHBA), and nonesterified fatty acids (NEFA) were measured throughout first lactation in 497 Holstein cows raised on a large commercial farm in northern Greece. All these traits are considered to be indicators of a cow's energy balance. An additional measure of BCS, EC, and blood serum glucose, BHBA, and NEFA concentrations were taken approximately 2 mo (61 +/- 23 d) before first calving. During first lactation, first service conception rate, conception rate in the first 305 d of lactation, interval from calving to conception, number of inseminations per conception, incidence of metritis, and incidence of reproductive problems of these cows were recorded; interval between first and second calving, and second lactation first service conception rate were also recorded. Random regression models were used to calculate weekly animal breeding values for first lactation BCS, EC, CEEB, glucose, BHBA, and NEFA. Single trait animal models were used to calculate breeding values for these traits measured on pregnant heifers before calving. Reproductive records were then regressed on animal breeding values for these energy balance-related traits to derive estimates of their genetic correlations. Several significant estimates were obtained. In general, traits that are known to be positively correlated with energy balance (BCS, EC, CEEB, and glucose) were found to have a favorable genetic relationship with reproduction, meaning that increased levels of the former will lead to an enhancement of the latter. On the other hand, traits known to be negatively correlated with energy balance (BHBA and NEFA) were found to have an unfavorable genetic association with reproductive traits. Body condition score, BHBA, and NEFA recorded early in lactation, and glucose concentrations measured in pregnant heifers had the highest genetic correlation with future reproductive performance. Results suggest that genetic selection for body energy and blood metabolites could facilitate the genetic improvement of fertility and overall reproductive efficiency of dairy cows.

  13. Current status and future directions of the population control policies in Korea.

    PubMed

    Cho, N H; Seo, M H

    1989-07-01

    Recent changes in demographic and socioeconomic conditions in Korea are reviewed, as are population control policies so that future policy directions can be established. Major data sources include the 1988 National Fertility and Family Health Survey and the 1985 Population and Housing Census of NBOS, EPB. The Korean population increased from 25.0 million in 1960 to 42.4 million in 1989. Population growth rate declined from 3.0% per annum to l.0% at the same time. The total fertility rate went down from 6.0/women to 1.6, from 1960 to 1987. This was due to a family planning program and socioeconomic development. In the Sixth Five-Year Plan (1987-1991), the government changed the demographic goals to further reduce the population growth rate to 0.96% by 1991. The estimated 1987 population of 41.6 million should reach 43.2 million by 1991. Korea will face 3 major population problems: an increase of the elderly population, rapid urbanization and shortage of resources. Emigration programs have been carried out to relieve the pressure of population. For the last 29 years, rural to urban migration has existed. A national family planning program exists. 16.4 million acceptors have received contraception under this program. There are, however, a number of problems. Reduction in population growth will help the world food supply problem and the housing shortage. Energy use has grown. Population and environmental planning should work together. Goals should change from reduction of fertility to eliminating problems with contraceptive acceptance and use effectiveness. There should be a greater choice of methods of contraception. The government functions of the family planning program should be given over to private organizations. The family planning program should be integrated with public health programs. Acceptors should pay for their contraceptives. The family planning program should enlarge its realm of activities. The information, education, communication part of the program should be revised. Individual program activities should be evaluated. Appendix 1 presents new population projections for 1987-2020. Changes in composition of the population are given in table form in Appendix 2.

  14. Tree ring evidence for limited direct CO2 fertilization of forests over the 20th century

    NASA Astrophysics Data System (ADS)

    Gedalof, Ze'ev; Berg, Aaron A.

    2010-09-01

    The effect that rising atmospheric CO2 levels will have on forest productivity and water use efficiency remains uncertain, yet it has critical implications for future rates of carbon sequestration and forest distributions. Efforts to understand the effect that rising CO2 will have on forests are largely based on growth chamber studies of seedlings, and the relatively small number of FACE sites. Inferences from these studies are limited by their generally short durations, artificial growing conditions, unnatural step-increases in CO2 concentrations, and poor replication. Here we analyze the global record of annual radial tree growth, derived from the International Tree ring Data Bank (ITRDB), for evidence of increasing growth rates that cannot be explained by climatic change alone, and for evidence of decreasing sensitivity to drought. We find that approximately 20 percent of sites globally exhibit increasing trends in growth that cannot be attributed to climatic causes, nitrogen deposition, elevation, or latitude, which we attribute to a direct CO2 fertilization effect. No differences were found between species in their likelihood to exhibit growth increases attributable to CO2 fertilization, although Douglas-fir (Pseudotsuga menziesii) and ponderosa pine (Pinus ponderosa), the two most commonly sampled species in the ITRDB, exhibit a CO2 fertilization signal at frequencies very near their upper and lower confidence limits respectively. Overall these results suggest that CO2 fertilization of forests will not counteract emissions or slow warming in any substantial fashion, but do suggest that future forest dynamics may differ from those seen today depending on site conditions and individual species' responses to elevated CO2.

  15. Nutritional status, fertility and factors associated with anaemia: a cross sectional study among a rural population of Muslim women in Assam, India.

    PubMed

    Haloi, Anjali; Limbu, Dhruba Kumar

    2013-01-01

    In the present study an attempt has been made to report on the nutritional status of the Assamese Muslim women of Dadara and Agyathuri villages of the Kamrup district in Assam, India on their basis of body mass index (BMI) and haemoglobin (hb) content. Cross sectional data on 1034 women belonging to the age group of 19 years and above were collected following internationally accepted standards. The fertility of mothers by BMI range was found to be highest (6.50 (mean) +/- 0.14 (SE) and range being 1-11) amongst underweight mothers. The one-way analysis of variance (ANOVA) test of BMI and fertility shows significant relation between different BMI groups withp < 0.01. Highest haemoglobin levels were recorded in the age group of < or = 23 years with a mean of 11.61 +/- 0.06 g/dl, the range being 9.8-13.9 g/dl. Whereas lowest levels of haemoglobin were found in the age groups of 44+ years having a mean value of 10.26 +/- 0.04 g/dl and a range of 9.2-11.8 g/dl. The ANOVA analysis for haemoglobin content and corresponding fertility rates show significant difference between different hemoglobin levels with their live births at p < 0.01. The summary of ANOVA analysis for haemoglobin and BMI range shows the significant difference between groups i.e., normal, overweight and underweight. The t-value and F-ratio is 118.61 and 14068.42, respectively, which is significant at 1% probability. The authors conclude a general trend in the study population of women with high fertility having poor nutritional status. These findings might be important in formulating responsive health policies in an underdeveloped region.

  16. Projected land photosynthesis constrained by changes in the seasonal cycle of atmospheric CO2.

    PubMed

    Wenzel, Sabrina; Cox, Peter M; Eyring, Veronika; Friedlingstein, Pierre

    2016-10-27

    Uncertainties in the response of vegetation to rising atmospheric CO 2 concentrations contribute to the large spread in projections of future climate change. Climate-carbon cycle models generally agree that elevated atmospheric CO 2 concentrations will enhance terrestrial gross primary productivity (GPP). However, the magnitude of this CO 2 fertilization effect varies from a 20 per cent to a 60 per cent increase in GPP for a doubling of atmospheric CO 2 concentrations in model studies. Here we demonstrate emergent constraints on large-scale CO 2 fertilization using observed changes in the amplitude of the atmospheric CO 2 seasonal cycle that are thought to be the result of increasing terrestrial GPP. Our comparison of atmospheric CO 2 measurements from Point Barrow in Alaska and Cape Kumukahi in Hawaii with historical simulations of the latest climate-carbon cycle models demonstrates that the increase in the amplitude of the CO 2 seasonal cycle at both measurement sites is consistent with increasing annual mean GPP, driven in part by climate warming, but with differences in CO 2 fertilization controlling the spread among the model trends. As a result, the relationship between the amplitude of the CO 2 seasonal cycle and the magnitude of CO 2 fertilization of GPP is almost linear across the entire ensemble of models. When combined with the observed trends in the seasonal CO 2 amplitude, these relationships lead to consistent emergent constraints on the CO 2 fertilization of GPP. Overall, we estimate a GPP increase of 37 ± 9 per cent for high-latitude ecosystems and 32 ± 9 per cent for extratropical ecosystems under a doubling of atmospheric CO 2 concentrations on the basis of the Point Barrow and Cape Kumukahi records, respectively.

  17. Field fertility of sex-sorted and non-sorted frozen-thawed stallion spermatozoa.

    PubMed

    Clulow, J R; Buss, H; Sieme, H; Rodger, J A; Cawdell-Smith, A J; Evans, G; Rath, D; Morris, L H A; Maxwell, W M C

    2008-11-01

    In the 2004/2005 breeding season, the fertility of sex-sorted (SS) and non-sorted (NS) frozen stallion spermatozoa from two Hannovarian stallions was compared. A hysteroscopic insemination technique [Morris, L.H., Tiplady, C., Allen, W.R., 2003a. Pregnancy rates in mares after a single fixed time hysteroscopic insemination of low numbers of frozen-thawed spermatozoa onto the uterotubal junction. Equine Vet. J. 35, 197-201] was used to deposit low doses (6, 13 or 25 x 10(6) frozen-thawed SS or NS spermatozoa) onto the utero-tubal junction at 32 or 38 h after the administration of Chorulon (2500 IU, Intervet). Fertility was low, with one pregnancy (13 x 10(6) spermatozoa, 500 microL) obtained after artificial insemination with frozen SS spermatozoa (n=29 cycles) which resulted in the birth of a filly. Two pregnancies were obtained in mares inseminated with 6 x 10(6) NS spermatozoa in 250 microL (n=31 cycles). Mares failing to conceive on two experimental cycles were allocated to the conventional insemination group. Insemination with >500 x 10(6) motile NS frozen-thawed spermatozoa, yielded satisfactory per cycle conception rates (35.5%, 22/62) for both stallions combined and was within the values of their normal fertility as quoted by the stud's records. This suggests that the quality of the frozen semen was acceptable and that the freezing processes yielded viable spermatozoa capable of fertilisation. The poor fertility after hysteroscopic insemination with low doses of sex-sorted or non-sorted spermatozoa from the same stallions may be directly attributable to the low dose insemination conditions with frozen-thawed rather than sex-sorted spermatozoa.

  18. Genetic correlations between methane production and fertility, health, and body type traits in Danish Holstein cows.

    PubMed

    Zetouni, L; Kargo, M; Norberg, E; Lassen, J

    2018-03-01

    Our aim was to investigate the genetic correlations between CH 4 production and body conformation, fertility, and health traits in dairy cows. Data were collected from 10 commercial Holstein herds in Denmark, including 5,758 cows with records for body conformation traits, 7,390 for fertility traits, 7,439 for health traits, and 1,397 with individual CH 4 measurements. Methane production was measured during milking in automatic milking systems, using a sniffer approach. Correlations between CH 4 and several different traits were estimated. These traits were interval between calving and first insemination, interval between first and last insemination, number of inseminations, udder diseases, other diseases, height, body depth, chest width, dairy character, top line, and body condition score. Bivariate linear models were used to estimate the genetic parameters within and between CH 4 and the other traits. In general, the genetic correlations between CH 4 and the traits investigated were low. The heritability of CH 4 was 0.25, and ranged from 0.02 to 0.07 for fertility and health traits, and from 0.17 to 0.74 for body conformation traits. Further research with a larger data set should be performed to more accurately establish how CH 4 relates to fertility, health, and body conformation traits in dairy cattle. This will be useful in the design of future breeding goals that consider the production of CH 4 . The Authors. Published by the Federation of Animal Science Societies and Elsevier Inc. on behalf of the American Dairy Science Association®. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).

  19. Is the idea of a fast block to polyspermy based on artifact?

    PubMed

    Dale, Brian

    2014-08-01

    This purpose of this review is to look at the experimental evidence, both kinetic and electrophysiological, that led to the hypothesis of a fast electrical block to polyspermy in sea urchin eggs. The idea of a fast partial block, forwarded in the 1950's, that would reduce the receptivity of the egg surface by 1/20th following its interaction with the fertilizing spermatozoon, was based on experiments that treated fertilization as a first order chemical reaction. Here, I outline the criticisms of the Rothschild theory and demonstrate that the hypothesis of a fast partial block to polyspermy is unfounded. Notwithstanding, it was suggested in the 1970's that the membrane depolarization, induced by the fertilizing spermatozoon, prevented the interaction of supernumerary spermatozoa, the fast electrical block to polyspermy. While trans-membrane voltage recording has permitted a better understanding of the sequence of events occurring at fertilization, there is no evidence that depolarization prevents the interaction of supernumerary spermatozoa. Sperm entry is prevented at positive and negative potentials, in the voltage clamp configuration, however this is an artifact caused by the currents injected into the egg employed to hold the voltage constant in a non-physiological range. At permissive voltages, around -20 mV, where the current required to hold the voltage is minimal, only one spermatozoon normally enters the egg. Thus, irrespective of the egg voltage, the fertilizing spermatozoon is, in any case, attached to a privileged interaction site that permits entry and distinguishes it from supernumerary spermatozoa. Competence for monospermy is acquired during oocyte maturation and data on cortical organization in echinoderm eggs points to the actin filament system for regulating sperm entry. Copyright © 2014 Elsevier Inc. All rights reserved.

  20. Costs of medically assisted reproduction treatment at specialized fertility clinics in the Danish public health care system: results from a 5-year follow-up cohort study.

    PubMed

    Christiansen, Terkel; Erb, Karin; Rizvanovic, Amra; Ziebe, Søren; Mikkelsen Englund, Anne L; Hald, Finn; Boivin, Jacky; Schmidt, Lone

    2014-01-01

    To examine the costs to the public health care system of couples in medically assisted reproduction. Longitudinal cohort study of infertile couples initiating medically assisted reproduction treatment. Specialized public fertility clinics in Denmark. Seven hundred and thirty-nine couples having no child at study entry and with data on kind of treatment and live birth (yes/no) for each treatment attempt at the specialized public fertility clinic. Treatment data for medically assisted reproduction attempts conducted at the public fertility clinics were abstracted from medical records. Flow diagrams were drawn for different standard treatment cycles and direct costs at each stage in the flow charts were measured and valued by a bottom-up procedure. Indirect costs were distributed to each treatment cycle on the basis of number of visits as basis. Costs were adjusted to 2012 prices using a constructed medical price index. Live birth, costs. Total costs per live birth in 2012 prices were estimated to 10,755€. Costs per treated couple - irrespective of whether the treatment was terminated by a live birth or not - were estimated at 6607€. Costs per live birth of women <35 years at treatment initiation were 9338€ and 15,040€ for women ≥35 years. The public costs for live births after conception with medically assisted reproduction treatment are relatively modest. The results can be generalized to public fertility treatment in Denmark and to other public treatment settings with similar limitations in numbers of public treatment cycles offered. © 2013 Nordic Federation of Societies of Obstetrics and Gynecology.

  1. Is ovarian reserve associated with body mass index and obesity in reproductive aged women? A meta-analysis.

    PubMed

    Moslehi, Nazanin; Shab-Bidar, Sakineh; Ramezani Tehrani, Fahimeh; Mirmiran, Parvin; Azizi, Fereidoun

    2018-05-07

    The associations of body mass index (BMI) and obesity with ovarian reserve are controversial. This systematic review and meta-analysis was conducted to investigate the associations in reproductive-aged women. PubMed and Scopus were searched up to December, 2016. Original studies on the association of BMI with ovarian reserve markers, anti-Mullerian hormone (AMH), follicle-stimulating hormone (FSH), inhibin β, and antral follicle count (AFC), either according to BMI categories or a continuous variable, were selected. Analyses were stratified into three groups based on polycystic ovary syndrome (PCOS) and fertility status of women. Of 4,055 records identified, 45 studies were eligible for inclusion. Comparing the obese with nonobese, the pooled mean differences (MDs) and 95% confidence intervals (CIs) were -1.08 (95% CIs -1.52, -0.63) ng/mL for AMH, -0.22 (95% CIs -0.39, -0.06) mIU/mL for FSH, -0.09 (95% CIs -0.60, 0.42) for AFC, and -21.06 (95% CIs -41.18, -0.85) pg/mL for inhibin β in overall populations. The MDs were significant for AMH in fertile non-PCOS and PCOS women, and for FSH only in PCOS women. Fisher's Z showed significant correlations of BMI with AMH in the overall populations (-0.15 [95% CIs -0.20, -0.11]) and in all subgroups, and with FSH in the fertile non-PCOS women (-0.16 [95% CIs -0.28, -0.04]). Ovarian reserve markers of AMH and FSH are significantly lower in obese than in nonobese women, and BMI is negatively correlated with AMH in all study populations, and with FSH in fertile non-PCOS subgroups. PCOS and fertility status do not appear to affect the associations.

  2. Associations between strain, herd size, age at first calving, culling reason and lifetime performance characteristics in Holstein-Friesian cows.

    PubMed

    Adamczyk, K; Makulska, J; Jagusiak, W; Węglarz, A

    2017-02-01

    Cow longevity and lifetime performance traits are good indicators of breeding effectiveness and animal welfare. They are also interrelated with the economics of dairy herd. Unfortunately, a high milk yield is often associated with deteriorated cow health and fertility and, consequently, with an increased culling rate. This situation, observed also in the Polish population of Holstein-Friesian cattle, inspired us to undertake a study on the associations between some factors and lifetime performance characteristics. The data set consisted of the records on 135 496 cows, including 131 526 of the Black and White strain (BW), and 3970 of the Red and White strain (RW) covered by performance recording and culled in 2012. It was found that cows of the BW strain and those from the largest herds (>100 cows) reached higher lifetime and mean daily energy-corrected milk (ECM) yields than cows of the RW strain and those from smaller herds culled at a similar age. Cows youngest at first calving (<2.0 years) were characterised by the highest lifetime ECM yield. It indicates that heifers can be bred even when they are younger than 15 to 16 months with no significant negative effect on their later performance. Infertility and reproduction problems (39.6%) and udder diseases (15.5%) constituted the most frequent reasons for cow culling. Cow longevity and lifetime productivity were considerably affected by the interactions between the studied factors.

  3. Increased Needle Nitrogen Contents Did Not Improve Shoot Photosynthetic Performance of Mature Nitrogen-Poor Scots Pine Trees.

    PubMed

    Tarvainen, Lasse; Lutz, Martina; Räntfors, Mats; Näsholm, Torgny; Wallin, Göran

    2016-01-01

    Numerous studies have shown that temperate and boreal forests are limited by nitrogen (N) availability. However, few studies have provided a detailed account of how carbon (C) acquisition of such forests reacts to increasing N supply. We combined measurements of needle-scale biochemical photosynthetic capacities and continuous observations of shoot-scale photosynthetic performance from several canopy positions with simple mechanistic modeling to evaluate the photosynthetic responses of mature N-poor boreal Pinus sylvestris to N fertilization. The measurements were carried out in August 2013 on 90-year-old pine trees growing at Rosinedalsheden research site in northern Sweden. In spite of a nearly doubling of needle N content in response to the fertilization, no effect on the long-term shoot-scale C uptake was recorded. This lack of N-effect was due to strong light limitation of photosynthesis in all investigated canopy positions. The effect of greater N availability on needle photosynthetic capacities was also constrained by development of foliar phosphorus (P) deficiency following N addition. Thus, P deficiency and accumulation of N in arginine appeared to contribute toward lower shoot-scale nitrogen-use efficiency in the fertilized trees, thereby additionally constraining tree-scale responses to increasing N availability. On the whole our study suggests that the C uptake response of the studied N-poor boreal P. sylvestris stand to enhanced N availability is constrained by the efficiency with which the additional N is utilized. This efficiency, in turn, depends on the ability of the trees to use the greater N availability for additional light capture. For stands that have not reached canopy closure, increase in leaf area following N fertilization would be the most effective way for improving light capture and C uptake while for mature stands an increased leaf area may have a rather limited effect on light capture owing to increased self-shading. This raises the question if N limitation in boreal forests acts primarily by constraining growth of young stands while the commonly recorded increase in stem growth of mature stands following N addition is primarily the result of altered allocation and only to a limited extent the result of increased stand C-capture.

  4. Hydatidosis of camel (Camelus dromedarius) at Jijiga municipal abattoir, Eastern Ethiopia: prevalence, associated risk factors and financial implication.

    PubMed

    Debela, Etana; Abdulahi, Buckhary; Megersa, Bekele; Kumsa, Bersissa; Abunna, Fufa; Sheferaw, Desie; Regassa, Alemayehu

    2015-12-01

    A cross-sectional study was conducted from November 2010 to May 2011 to estimate the prevalence of camel hydatidosis, associated risk factors and financial loss in Jijiga municipal abattoir, Somali Regional State, Eastern Ethiopia. Accordingly, of the total 400 inspected camel, 92 (23 %) camels and 109 organs were positive for hydatid cyst with the highest proportion recorded in lung (56 %) followed by liver (33.9 %), spleen (7.3 %) and kidneys (2.8 %). The prevalence of hydatidosis significantly varied among age categories (P < 0.05), sex (P < 0.05) and body condition score (P < 0.05) of camels. Hence, there is higher likelihood for occurrence of camel hydatidosis among the older age groups (OR 1.8, 95 % CI 1.2, 3.3), in female camels (OR 2.8, 95 % CI 1.7, 4.7) and in poor body conditioned camels (OR 4.1, 95 % CI 2.2, 7.9) than younger camels, males and camels with good body condition score, respectively. Of the total 288 examined cysts for fertility and viability, 59.7 % (172/288) were fertile while the rest 24.0 % (69/288) cysts were sterile. Of the 172 fertile cysts 69.8 % (n = 120) were viable and 30.2 % (n = 52) were non-viable. The rest 16.3 % (47/288) cysts were found dead. It was also observed that the pulmonary and hepatic cysts had fertility rate of 63.7 % (116/182) and 57.4 % (54/94), respectively. The total annual direct financial loss recorded in this study as result of organs condemnation due to hydatid cyst, was 12,147.75 Ethiopian birrs ($714.57 or $7.77/camel). If this value could be extrapolated to the infected camel population of the region, financial loss due to hydatidosis could be enormous. In conclusion, this study showed the importance of hydatidosis and the associated direct financial loss due to the condemnation of organs affected by hydatid cyst in the study area.

  5. Appropriate Technology, Energy and Food Production in an Industrial Arts Curriculum.

    ERIC Educational Resources Information Center

    Pytlik, Edward; Scanlin, Dennis

    1979-01-01

    With modern agriculture, the growing, processing, packaging, and distribution of food fit well into an industrial arts curriculum. Many areas of this system need closer attention: the high cost of energy in food production, the problems of land preparation, fertilizers, irrigation, food processing, and agriculture in an industrial arts curriculum.…

  6. Cystic Fibrosis through a Female Perspective: Psychosocial Issues and Information Concerning Puberty and Motherhood.

    ERIC Educational Resources Information Center

    Johannesson, Marie; Carlson, Margareta; Brucefors, Agneta Bergsten; Hjelte, Lena

    1998-01-01

    Investigates psychosocial issues concerning puberty and motherhood among adult women with cystic fibrosis (CF) to see how they had obtained information on these matters and how they would like information to be given. Results reveal problems with destructive behavior during puberty. Information about puberty and fertility should be given…

  7. The demography of the Arab Republic of Egypt: population issues and policies.

    PubMed

    Holmberg, I

    1981-01-01

    The author examines some aspects of population growth in Egypt. Recent trends in fertility, mortality, urbanization, industrialization, regional development, and internal migation are described. The demographic and socioeconomic consequences of rapid population growth are considered, and the possibility of formulating government policies to alleviate problems associated with rapid growth is discussed

  8. [Feminists' approach to population problems: new paradigm or Utopia?].

    PubMed

    Kono, S

    1997-05-01

    The author first notes that, partly because of events occurring at the International Conference on Population and Development that took place in Cairo in 1994, a consensus has emerged that population programs based on a philosophy of empowering women and focusing on reproductive health are more likely to be effective than programs that focus on providing family planning services and achieving demographic targets. Some reservations about this consensus are then expressed. The author points out the difficulties inherent in widening the mandate of family planning programs in an era of diminished resources for international assistance, the past success of such programs in reducing fertility with limited resources, and the inherent contradictions in following a laissez-faire attitude toward reproduction in such regions as Sub-Saharan Africa, where economies and political systems are often in crisis, health services are minimal, and desired levels of fertility both way above current levels and far above the replacement level. While not challenging the value of the Cairo philosophy, the need to move from rhetoric to reality in the face of the world's current population problems is stressed.

  9. A new pulping process for wheat straw to reduce problems with the discharge of black liquor.

    PubMed

    Huang, Guolin; Shi, Jeffrey X; Langrish, Tim A G

    2007-11-01

    Aqueous ammonia mixed with caustic potash as wheat straw pulping liquor was investigated. The caustic potash did not only reduce the NH3 usage and cooking time, but also provided a potassium source as a fertilizer in the black liquor. Excess NH3 in the black liquor was recovered and reused by batch distillation with a 98% recovery rate of free NH3. The black liquor was further treated for reuse by coagulation under alkaline conditions. The effects of different flocculation conditions, such as the dosage of 10% aluminium polychloride, the dosage of 0.1% polyacrylamide, the reaction temperature and the pH of the black liquor on the flocculating process were studied. The supernatant was recycled as cooking liquor by adding extra NH4OH and KOH. The amount of delignification and the pulp yield for the process remained steady at 82-85% and 48-50%, respectively, when reusing the supernatant four times. The coagulated residues could be further processed as solid fertilizers. This study provided a new pulping process for wheat straw to reduce problems of discharge black liquor.

  10. Experiential avoidance, self-compassion, self-judgment and coping styles in infertility.

    PubMed

    Cunha, Marina; Galhardo, Ana; Pinto-Gouveia, José

    2016-12-01

    This study sought out to explore the existence of differences regarding emotion regulation processes (psychological inflexibility/experiential avoidance, self-judgment and self-compassion) and coping styles (emotional/detached, avoidant and rational) in three different groups of couples: 120 fertile couples (FG), 147 couples with an infertility diagnosis who were pursuing medical treatment for their fertility problem(s) (IG), and 59 couples with infertility applying for adoption (AG). Cross-sectional survey, using the couple as unit of analysis. Participants filled in paper-pencil questionnaires assessing coping styles, psychological inflexibility/experiential avoidance, self-judgment and self-compassion. IG couples, and particularly women, tend to use more experiential avoidance and self-judgment mechanisms and less emotional/detached coping style. When compared to FG couples, IG and AG couples tend to apply more avoidant coping strategies. AG couples showed higher self-compassion. Findings suggest that emotion regulation processes may be an important target in psychological interventions for patients dealing with infertility and with the demands of medical treatment. Copyright © 2016 Elsevier B.V. All rights reserved.

  11. Effect of Fertilization on Soil Fertility and Nutrient Use Efficiency at Potatoes

    NASA Astrophysics Data System (ADS)

    Neshev, Nesho; Manolov, Ivan

    2016-04-01

    The effect of fertilization on soil fertility, yields and nutrient use efficiency of potatoes grown under field experimental conditions was studied. The trail was conducted on shallow brown forest soil (Cambisols-coarse) during the vegetation periods of 2013 to 2015. The variants of the experiment were: control, N140; P80; K100; N140P80; N140K100; P80K100; N140P80K100; N140P80K100Mg33. The applied fertilization slightly decreased soil's pH after the harvest of potatoes compared to the soil pH their planting. Decreasing of pH was more severe at variant N (from 5,80 to 4,19 in 2014). The mineral nitrogen content in the soil after the harvest of potatoes was lower for the variants P, K and PK. The positive effect of fertilization on soil fertility after the end of the trails was more pronounced at variants NPK and NPKMg. The content of available nitrogen, phosphorus and potassium forms for these variants was the highest for each year. The highest content of mineral nitrogen was observed in 2013 (252,5 and 351,1 mg/1000g, respectively for variants NPK and NPKMg). It was due to extremely dry weather conditions during the vegetation in this year. Soil content of mineral N for the next two years was lower. The same tendency was observed for phosphorus and potassium was observed. In 2013 the P2O5 and K2O content in soil was the highest for the variants with full mineral fertilization - NPK (64,4 and 97,6 mg 100g-1 respectively for P2O5 and K2O) and NPKMg (65,2 and 88,0 mg 100g-1 respectively for P2O5 and K2O). The highest yields were recorded at variants NPK and NPKMg - 24,21 and 22,01 t ha-1, average for the studied period. The yield of variant NPK was 25 % higher than the yield from variant NP and 68 % higher than control. The partial factor productivity (PFPN, PFPP and PFPK) of the applied fertilizers was the highest at variant NPK. The PFPN (80,10 kg kg-1) for the yields of variant N was 57 % lower than the PFPN at variant NPK (180,36 kg kg-1). The PFPP and PFPK at variants P and K was approximately 57 and 47 % lower compared with variant NPK. Agronomic efficiency (AE) of applied nutrient was the highest for the combined NPK fertilization. The application only of N, P, K and PK combination without N was agronomically not effective practice. The combined NPK and NPKMg variants ensure the highest yields. The indicators of nutrient use efficiency (PFP and AE) were also the highest at these variants. Key words: Soil fertility, nutrient use efficiency, potatoes, yields,

  12. The effect of endoscopic sterilization on reproductive behavior and pair bond maintenance of feral pigeons (Columba livia).

    PubMed

    Heiderich, E; Failing, K; Lierz, M; Schildger, B

    2016-01-01

    Problems related to feral pigeons (Columba livia) in cities mainly result from their large numbers due to uncontrolled population growth. The aim of this study was to evaluate whether endoscopic guided sterilization affects the reproductive behavior of feral pigeons under experimental conditions, with the intention of assessing this technique as a potential method for feral pigeon population control. Five groups of four pairs of feral pigeons each were studied from 8 weeks before, to 7 weeks after sterilization. Both the male and female of the first pair of each group were sterilized, in the second pair only the female and in the third pair only the male was sterilized. The fourth pair acted as a control. All eggs laid were candled to assess fertility. Surgical sterilization had minimal effects on behavior and therefore seems not to have impact on possible field application for population control. All pairs maintained their pair bonds and continued to defend their nesting sites against other pigeons. Only one female copulated with a foreign fertile male while her primary partner was debilitated due to surgery, but returned to him as soon as he recovered. All eggs laid more than 5 days after male sterilization were infertile, whereas all control pairs had fertile eggs. Only one fertile clutch was produced, 5 days after the male's sterilization. Therefore it is assumed that males remain fertile for a limited period of time. Endoscopic sterilization seems to be a promising method for field control of feral pigeon populations and sterilization of the male only seems sufficient.

  13. Budgeting of major nutrients and the mitigation options for nutrient mining in semi-arid tropical agro-ecosystem of Tamil Nadu, India using NUTMON model.

    PubMed

    Surendran, U; Rama Subramoniam, S; Raja, P; Kumar, V; Murugappan, V

    2016-04-01

    Mining of nutrients from soil is a major problem in developing countries causing soil degradation and threaten long-term food production. The present study attempts to apply NUTrient MONitoring (NUTMON) model for carrying out nutrient budgeting to assess the stocks and flows of nitrogen (N), phosphorus (P), and potassium (K) in defined geographical unit based on the inputs, viz., mineral fertilizers, manures, atmospheric deposition, and sedimentation, and outputs, viz., harvested crop produces, residues, leaching, denitrification, and erosion losses. The study area covers Coimbatore and Erode Districts, which are potential agricultural areas in western agro-ecological zone of Tamil Nadu, India. The calculated nutrient balances for both the districts at district scale, using NUTMON methodology, were negative for nitrogen (N -3.3 and -10.1 kg ha(-1)) and potassium (K -58.6 and -9.8 kg ha(-1)) and positive for phosphorus (P +14.5 and 20.5 kg ha(-1)). Soil nutrient pool has to adjust the negative balance of N and K; there will be an expected mining of nutrient from the soil reserve. A strategy was attempted for deriving the fertilizer recommendation using Decision Support System for Integrated Fertilizer Recommendation (DSSIFER) to offset the mining in selected farms. The results showed that when DSSIFER recommended fertilizers are applied to crops, the nutrient balance was positive. NUTMON-Toolbox with DSSIFER would serve the purpose on enhancing soil fertility, productivity, and sustainability. The management options to mitigate nutrient mining with an integrated system approach are also discussed.

  14. New insights into male (in)fertility: the importance of NO

    PubMed Central

    Buzadzic, B; Vucetic, M; Jankovic, A; Stancic, A; Korac, A; Korac, B; Otasevic, V

    2015-01-01

    Infertility is a global problem that is on the rise, especially during the last decade. Currently, infertility affects approximately 10–15% of the population worldwide. The frequency and origin of different forms of infertility varies. It has been shown that reactive oxygen and nitrogen species (ROS and RNS) are involved in the aetiology of infertility, especially male infertility. Various strategies have been designed to remove or decrease the production of ROS and RNS in spermatozoa, in particular during in vitro fertilization. However, in recent years it has been shown that spermatozoa naturally produce a variety of ROS/RNS, including superoxide anion radical (O2⋅−), hydrogen peroxide and NO. These reactive species, in particular NO, are essential in regulating sperm capacitation and the acrosome reaction, two processes that need to be acquired by sperm in order to achieve fertilization potential. In addition, it has recently been shown that mitochondrial function is positively correlated with human sperm fertilization potential and quality and that NO and NO precursors increase sperm motility by increasing energy production in mitochondria. We will review the new link between sperm NO-driven redox regulation and infertility herein. A special emphasis will be placed on the potential implementation of new redox-active substances that modulate the content of NO in spermatozoa to increase fertility and promote conception. Linked Articles This article is part of a themed section on Pharmacology of the Gasotransmitters. To view the other articles in this section visit http://dx.doi.org/10.1111/bph.2015.172.issue-6 PMID:24601995

  15. [Effects of Rice Cultivar and Typical Soil Improvement Measures on the Uptake of Cd in Rice Grains].

    PubMed

    Wang, Mei-e; Peng, Chi; Chen, Wei-ping

    2015-11-01

    Cadmium pollution of rice is a big problem in agricultural food safety. The accident "Cd rice" occurred last year in Youxian County, Hunan Province caused serious social panic. In this study, trials on "Cd rice" controlling techniques specific to the Cd pollution in paddy soil in Youxian were investigated. It was suggested that the average Cd contents in rice grains of the rice variety "Zhu Liang You 06" in Datongqiao and Wangling were 0.167 and 0.127 mg x kg(-1), respectively, which were only equal to 20% of the contents of other varieties. The trials for stabilizing agents revealed that treatments of lime and mineral fertilizer decreased Cd contents in rice grains to 20-30% of the control. Plastic film-mulched treatment decreased the rice grain Cd to 50%. And combined treatment of plastic film-mulched and biochar and silicon foliar-fertilizer decreased 80% of rice Cd content. Single treatments of silicon foliar-fertilizer and combined treatment of silicon foliar-fertilizer and topdressing fertilizer decreased more than 90% of Cd content. Results of BCR revealed that the percentage of cationic exchangeable and/or carbonate associated Cd fraction was more than 55% for most of the soil samples. Lime treatment significantly decreased the percentage of cationic exchangeable and/or carbonate and oxides of Fe and Mn associated Cd and increased the crystalline structure of clay minerals associated Cd. The change rate reached about 20%. Our results suggested concentration of soil Cd and pH were the two significant factors impacting the uptake of Cd by rice grains.

  16. A qualitative study of Ottawa university students' awareness, knowledge and perceptions of infertility, infertility risk factors and assisted reproductive technologies (ART).

    PubMed

    Sabarre, Kelley-Anne; Khan, Zainab; Whitten, Amanda N; Remes, Olivia; Phillips, Karen P

    2013-08-20

    Awareness of infertility risk factors is an essential first step to safeguard future fertility. Whereas several studies have examined university students' awareness of female fertility and related risk factors, the topic of male infertility has not been well examined. The objective of this study was to assess young men and women's awareness, knowledge and perceptions of infertility, male and female infertility risk factors and assisted reproductive technologies (ART). Semi-structured interviews were conducted in 2008 with a multi-ethnic sample of sixteen male and twenty-three female Ottawa university students, followed by qualitative data analysis to identify major themes. Interview topics included awareness of male and female infertility risk factors, infertility diagnosis/treatments and personal options in the event of future infertility. Participants were generally familiar with infertility as a biomedical health problem, could identify sex-specific risk factors but overestimated fertility of women in their thirties and ART success rates. Reproductive health knowledge gaps and confusion of the physiological life-stage of menopause with infertility were apparent. Most participants would pursue in vitro fertilization or international adoption in the event of personal infertility. Some participants wished to use a 'natural' approach and were concerned with potential side effects of ART-related medications. The general awareness of infertility in young adults is promising and supports the potential uptake for health promotion of fertility preservation. This study underscores the continued need for comprehensive sexual and reproductive health education and promotion for adolescents and young adults.

  17. [Trends in our population growth].

    PubMed

    Delanghe, L

    1980-10-01

    The birth rate in Belgium decreased between 1964 and 1975, after which the birth rate again began to increase. This increase was not enough, however, to justify classifying Belgium's population as expansive. The decrease in fertility was due mainly to a decrease in the fertility of women in the highest fertility age groups. This development began to spread into lower age groups but was reversed by trends toward more traditional family patterns. After 1961, couples showed a preference for remaining childless for the first several years following their marriage, for the 2 child family, and for longer birth intervals. The decrease in fertility was greater among those with larger families, among the inhabitants of Flanders, among Catholics, among women who didn't work outside the home, and among those in higher income groups. Belgium has a relatively high infant mortality rate. 80% of the infant deaths in Belgium are perinatal in nature, due mainly to sociocultural and socio-hygienic factors. Trends in fertility and mortality have led to an increase in the average age of the Belgian population, which could lead to future socioeconomic problems. Social and economic incentives for having children should be instituted in order to secure the stability of the Belgian population, without infringing on the freedom of women to choose to work and have children. This would include aid for families in which both parents work, and economic aid so that those families in which the woman remains at home can afford to have more children. It is recommended that 30-35% of Belgian families should have 3 children instead of 2, if socioeconomic stability is to be achieved.

  18. A qualitative study of Ottawa university students’ awareness, knowledge and perceptions of infertility, infertility risk factors and assisted reproductive technologies (ART)

    PubMed Central

    2013-01-01

    Background Awareness of infertility risk factors is an essential first step to safeguard future fertility. Whereas several studies have examined university students’ awareness of female fertility and related risk factors, the topic of male infertility has not been well examined. The objective of this study was to assess young men and women’s awareness, knowledge and perceptions of infertility, male and female infertility risk factors and assisted reproductive technologies (ART). Methods Semi-structured interviews were conducted in 2008 with a multi-ethnic sample of sixteen male and twenty-three female Ottawa university students, followed by qualitative data analysis to identify major themes. Interview topics included awareness of male and female infertility risk factors, infertility diagnosis/treatments and personal options in the event of future infertility. Results Participants were generally familiar with infertility as a biomedical health problem, could identify sex-specific risk factors but overestimated fertility of women in their thirties and ART success rates. Reproductive health knowledge gaps and confusion of the physiological life-stage of menopause with infertility were apparent. Most participants would pursue in vitro fertilization or international adoption in the event of personal infertility. Some participants wished to use a ‘natural’ approach and were concerned with potential side effects of ART-related medications. Conclusions The general awareness of infertility in young adults is promising and supports the potential uptake for health promotion of fertility preservation. This study underscores the continued need for comprehensive sexual and reproductive health education and promotion for adolescents and young adults. PMID:23962162

  19. Addressing global health, economic, and environmental problems through family planning.

    PubMed

    Speidel, J Joseph; Grossman, Richard A

    2011-06-01

    Although obstetrician-gynecologists recognize the importance of managing fertility for the reproductive health of individuals, many are not aware of the vital effect they can have on some of the world's most pressing issues. Unintended pregnancy is a key contributor to the rapid population growth that in turn impairs social welfare, hinders economic progress, and exacerbates environmental degradation. An estimated 215 million women in developing countries wish to limit their fertility but do not have access to effective contraception. In the United States, half of all pregnancies are unplanned. Voluntary prevention of unplanned pregnancies is a cost-effective, humane way to limit population growth, slow environmental degradation, and yield other health and welfare benefits. Family planning should be a top priority for our specialty.

  20. Earthworm influence on N availability and the growth of Cecropia schreberiana in tropical pasture and forest soils

    Treesearch

    G. Gonzalez; X. Zou

    1999-01-01

    This greenhouse study examines the effects of Pontoscolex corethrurus on the growth of Cecropia scheberiana in forest and pasture soils. Four treatments (0, 2, 20 worms and 0 worms + urea fertilizer) were applied to the soils to test if earthworms affect nitrogen availability, and consequently the growth of C. scheberiana. We recorded the number of seedlings, leaves,...

Top