Sample records for reduction process general

  1. Oxidation-reduction processes in ground water at Naval Weapons Industrial Reserve Plant, Dallas, Texas

    USGS Publications Warehouse

    Jones, S.A.; Braun, Christopher L.; Lee, Roger W.

    2003-01-01

    Concentrations of trichloroethene in ground water at the Naval Weapons Industrial Reserve Plant in Dallas, Texas, indicate three source areas of chlorinated solvents?building 1, building 6, and an off-site source west of the facility. The presence of daughter products of reductive dechlorination of trichloroethene, which were not used at the facility, south and southwest of the source areas are evidence that reductive dechlorination is occurring. In places south of the source areas, dissolved oxygen concentrations indicated that reduction of oxygen could be the dominant process, particularly south of building 6; but elevated dissolved oxygen concentrations south of building 6 might be caused by a leaking water or sewer pipe. The nitrite data indicate that denitrification is occurring in places; however, dissolved hydrogen concentrations indicate that iron reduction is the dominant process south of building 6. The distributions of ferrous iron indicate that iron reduction is occurring in places south-southwest of buildings 6 and 1; dissolved hydrogen concentrations generally support the interpretation that iron reduction is the dominant process in those places. The generally low concentrations of sulfide indicate that sulfate reduction is not a key process in most sampled areas, an interpretation that is supported by dissolved hydrogen concentrations. Ferrous iron and dissolved hydrogen concentrations indicate that ferric iron reduction is the primary oxidation-reduction process. Application of mean first-order decay rates in iron-reducing conditions for trichloroethene, dichloroethene, and vinyl chloride yielded half-lives for those solvents of 231, 347, and 2.67 days, respectively. Decay rates, and thus half-lives, at the facility are expected to be similar to those computed. A weighted scoring method to indicate sites where reductive dechlorination might be likely to occur indicated strong evidence for anaerobic biodegradation of chlorinated solvents at six sites. In general, scores were highest for samples collected on the northeast side of the facility.

  2. INCORPORATING ENVIRONMENTAL AND ECONOMIC CONSIDERATIONS INTO PROCESS DESIGN: THE WASTE REDUCTION (WAR) ALGORITHM

    EPA Science Inventory

    A general theory known as the WAste Reduction (WASR) algorithm has been developed to describe the flow and the generation of potential environmental impact through a chemical process. This theory integrates environmental impact assessment into chemical process design Potential en...

  3. Heterotic reduction of Courant algebroid connections and Einstein-Hilbert actions

    NASA Astrophysics Data System (ADS)

    Jurčo, Branislav; Vysoký, Jan

    2016-08-01

    We discuss Levi-Civita connections on Courant algebroids. We define an appropriate generalization of the curvature tensor and compute the corresponding scalar curvatures in the exact and heterotic case, leading to generalized (bosonic) Einstein-Hilbert type of actions known from supergravity. In particular, we carefully analyze the process of the reduction for the generalized metric, connection, curvature tensor and the scalar curvature.

  4. Review of Manganese Processing for Production of TRIP/TWIP Steels, Part 2: Reduction Studies

    NASA Astrophysics Data System (ADS)

    Elliott, R.; Coley, K.; Mostaghel, S.; Barati, M.

    2018-02-01

    Production of ultrahigh-manganese steels is expected to result in significant increase in demand for low-carbon (LC) ferromanganese (FeMn) and silicomanganese (SiMn). Current manganese processing techniques are energy intensive and typically yield a high-carbon product. The present work therefore reviews available literature regarding carbothermic reduction of Mn oxides and ores, with the objective of identifying opportunities for future process development to mitigate the cost of LC FeMn and SiMn. In general, there is consensus that carbothermic reduction of Mn oxides and ores is limited by gasification of carbon. Conditions which enhance or bypass this step (e.g., by application of CH4) show higher rates of reduction at lower temperatures. This phenomenon has potential application in solid-state reduction of Mn ore. Other avenues for process development include optimization of the prereduction step in conventional FeMn production and metallothermic reduction as a secondary reduction step.

  5. Acoustical and Perceptual Comparison of Noise Reduction and Compression in Hearing Aids

    ERIC Educational Resources Information Center

    Brons, Inge; Houben, Rolph; Dreschler, Wouter A.

    2015-01-01

    Purpose: Noise reduction and dynamic-range compression are generally applied together in hearing aids but may have opposite effects on amplification. This study evaluated the acoustical and perceptual effects of separate and combined processing of noise reduction and compression. Design: Recordings of the output of 4 hearing aids for speech in…

  6. Economic Statistical Design of Integrated X-bar-S Control Chart with Preventive Maintenance and General Failure Distribution

    PubMed Central

    Caballero Morales, Santiago Omar

    2013-01-01

    The application of Preventive Maintenance (PM) and Statistical Process Control (SPC) are important practices to achieve high product quality, small frequency of failures, and cost reduction in a production process. However there are some points that have not been explored in depth about its joint application. First, most SPC is performed with the X-bar control chart which does not fully consider the variability of the production process. Second, many studies of design of control charts consider just the economic aspect while statistical restrictions must be considered to achieve charts with low probabilities of false detection of failures. Third, the effect of PM on processes with different failure probability distributions has not been studied. Hence, this paper covers these points, presenting the Economic Statistical Design (ESD) of joint X-bar-S control charts with a cost model that integrates PM with general failure distribution. Experiments showed statistically significant reductions in costs when PM is performed on processes with high failure rates and reductions in the sampling frequency of units for testing under SPC. PMID:23527082

  7. Adiabatic reduction of a model of stochastic gene expression with jump Markov process.

    PubMed

    Yvinec, Romain; Zhuge, Changjing; Lei, Jinzhi; Mackey, Michael C

    2014-04-01

    This paper considers adiabatic reduction in a model of stochastic gene expression with bursting transcription considered as a jump Markov process. In this model, the process of gene expression with auto-regulation is described by fast/slow dynamics. The production of mRNA is assumed to follow a compound Poisson process occurring at a rate depending on protein levels (the phenomena called bursting in molecular biology) and the production of protein is a linear function of mRNA numbers. When the dynamics of mRNA is assumed to be a fast process (due to faster mRNA degradation than that of protein) we prove that, with appropriate scalings in the burst rate, jump size or translational rate, the bursting phenomena can be transmitted to the slow variable. We show that, depending on the scaling, the reduced equation is either a stochastic differential equation with a jump Poisson process or a deterministic ordinary differential equation. These results are significant because adiabatic reduction techniques seem to have not been rigorously justified for a stochastic differential system containing a jump Markov process. We expect that the results can be generalized to adiabatic methods in more general stochastic hybrid systems.

  8. Neuroimaging studies of practice-related change: fMRI and meta-analytic evidence of a domain-general control network for learning.

    PubMed

    Chein, Jason M; Schneider, Walter

    2005-12-01

    Functional magnetic resonance imaging and a meta-analysis of prior neuroimaging studies were used to characterize cortical changes resulting from extensive practice and to evaluate a dual-processing account of the neural mechanisms underlying human learning. Three core predictions of the dual processing theory are evaluated: 1) that practice elicits generalized reductions in regional activity by reducing the load on the cognitive control mechanisms that scaffold early learning; 2) that these control mechanisms are domain-general; and 3) that no separate processing pathway emerges as skill develops. To evaluate these predictions, a meta-analysis of prior neuroimaging studies and a within-subjects fMRI experiment contrasting unpracticed to practiced performance in a paired-associate task were conducted. The principal effect of practice was found to be a reduction in the extent and magnitude of activity in a cortical network spanning bilateral dorsal prefrontal, left ventral prefrontal, medial frontal (anterior cingulate), left insular, bilateral parietal, and occipito-temporal (fusiform) areas. These activity reductions are shown to occur in common regions across prior neuroimaging studies and for both verbal and nonverbal paired-associate learning in the present fMRI experiment. The implicated network of brain regions is interpreted as a domain-general system engaged specifically to support novice, but not practiced, performance.

  9. Iodine retention during evaporative volume reduction

    DOEpatents

    Godbee, H.W.; Cathers, G.I.; Blanco, R.E.

    1975-11-18

    An improved method for retaining radioactive iodine in aqueous waste solutions during volume reduction is disclosed. The method applies to evaporative volume reduction processes whereby the decontaminated (evaporated) water can be returned safely to the environment. The method generally comprises isotopically diluting the waste solution with a nonradioactive iodide and maintaining the solution at a high pH during evaporation.

  10. Production of oxygen from lunar ilmenite

    NASA Technical Reports Server (NTRS)

    Zhao, Y.; Shadman, F.

    1990-01-01

    The following subjects are addressed: (1) the mechanism and kinetics of carbothermal reduction of simulated lunar ilmenite using carbon and, particularly, CO as reducing agents; (2) the determination of the rate-limiting steps; (3) the investigation of the effect of impurities, particularly magnesium; (4) the search for catalysts suitable for enhancement of the rate-limiting step; (5) the comparison of the kinetics of carbothermal reduction with those of hydrogen reduction; (6) the study of the combined use of CO and hydrogen as products of gasification of carbonaceous solids; (7) the development of reduction methods based on the use of waste carbonaceous compounds for the process; (8) the development of a carbothermal reaction path that utilizes gasification of carbonaceous solids to reducing gaseous species (hydrocarbons and carbon monoxide) to facilitate the reduction reaction kinetics and make the process more flexible in using various forms of carbonaceous feeds; (9) the development of advanced gas separation techniques, including the use of high-temperature ceramic membranes; (10) the development of an optimum process flow sheet for carbothermal reduction, and comparison of this process with the hydrogen reduction scheme, as well as a general comparison with other leading oxygen production schemes; and (11) the use of new and advanced material processing and separation techniques.

  11. Statistical iterative reconstruction for streak artefact reduction when using multidetector CT to image the dento-alveolar structures.

    PubMed

    Dong, J; Hayakawa, Y; Kober, C

    2014-01-01

    When metallic prosthetic appliances and dental fillings exist in the oral cavity, the appearance of metal-induced streak artefacts is not avoidable in CT images. The aim of this study was to develop a method for artefact reduction using the statistical reconstruction on multidetector row CT images. Adjacent CT images often depict similar anatomical structures. Therefore, reconstructed images with weak artefacts were attempted using projection data of an artefact-free image in a neighbouring thin slice. Images with moderate and strong artefacts were continuously processed in sequence by successive iterative restoration where the projection data was generated from the adjacent reconstructed slice. First, the basic maximum likelihood-expectation maximization algorithm was applied. Next, the ordered subset-expectation maximization algorithm was examined. Alternatively, a small region of interest setting was designated. Finally, the general purpose graphic processing unit machine was applied in both situations. The algorithms reduced the metal-induced streak artefacts on multidetector row CT images when the sequential processing method was applied. The ordered subset-expectation maximization and small region of interest reduced the processing duration without apparent detriments. A general-purpose graphic processing unit realized the high performance. A statistical reconstruction method was applied for the streak artefact reduction. The alternative algorithms applied were effective. Both software and hardware tools, such as ordered subset-expectation maximization, small region of interest and general-purpose graphic processing unit achieved fast artefact correction.

  12. THE WASTE REDUCTION (WAR) ALGORITHM: ENVIRONMENTAL IMPACTS, ENERGY CONSUMPTION, AND ENGINEERING ECONOMICS

    EPA Science Inventory

    A general theory known as the WAste Reduction (WAR) algorithm has been developed to describe the flow and the generation of potential environmental impact through a chemical process. This theory defines potential environmental impact indexes that characterize the generation and t...

  13. Oxidation-reduction catalyst and its process of use

    NASA Technical Reports Server (NTRS)

    Schryer, Jacqueline L. (Inventor); Oglesby, Donald M. (Inventor); Jordan, Jeffrey D. (Inventor); Watkins, Anthony Neal (Inventor)

    2008-01-01

    This invention relates generally to a ruthenium stabilized oxidation-reduction catalyst useful for oxidizing carbon monoxide, and volatile organic compounds, and reducing nitrogen oxide species in oxidizing environments, substantially without the formation of toxic and volatile ruthenium oxide species upon said oxidizing environment being at high temperatures.

  14. THE WASTE REDUCTION (WAR) ALGORITHM: ENVIRONMENTAL IMPACTS, ENERGY CONSUMPTION, AND ENGINEERING ECONOMICS

    EPA Science Inventory

    A general theory known as the Waste Reduction (WAR) Algorithm has been developed to describe the flow and the generation of potential environmental impact through a chemical process. The theory defines indexes that characterize the generation and the output of potential environm...

  15. The Thermit Reaction: A Dazzling Thermochemical Demonstration.

    ERIC Educational Resources Information Center

    Kauffman, George B.

    1997-01-01

    Describes an outdoor scientific demonstration of metal reduction, a reaction known as the thermit process. Heat from an ignition mixture is required to initiate the reaction, which then becomes self-sustaining. The demonstration provides a dazzling introduction to such fundamental general chemistry topics as oxidation-reduction, metallurgy,…

  16. Chemical processing of lunar materials

    NASA Technical Reports Server (NTRS)

    Criswell, D. R.; Waldron, R. D.

    1979-01-01

    The paper highlights recent work on the general problem of processing lunar materials. The discussion covers lunar source materials, refined products, motivations for using lunar materials, and general considerations for a lunar or space processing plant. Attention is given to chemical processing through various techniques, including electrolysis of molten silicates, carbothermic/silicothermic reduction, carbo-chlorination process, NaOH basic-leach process, and HF acid-leach process. Several options for chemical processing of lunar materials are well within the state of the art of applied chemistry and chemical engineering to begin development based on the extensive knowledge of lunar materials.

  17. Reductive dechlorination of chlorinated ethenes under oxidation-reduction conditions and potentiometric surfaces in two trichloroethene-contaminated zones at the Double Eagle and Fourth Street Superfund sites in Oklahoma City, Oklahoma

    USGS Publications Warehouse

    Braun, Christopher L.

    2004-01-01

    The Double Eagle Refining Superfund site and the Fourth Street Abandoned Refinery Superfund site are in northeast Oklahoma City, Oklahoma, adjacent to one another. The Double Eagle facility became a Superfund site on the basis of contamination from lead and volatile organic compounds; the Fourth Street facility on the basis of volatile organic compounds, pesticides, and acid-base neutral compounds. The study documented in this report was done to investigate whether reductive dechlorination of chlorinated ethenes under oxidation-reduction conditions is occurring in two zones of the Garber-Wellington aquifer (shallow zone 30–60 to 75 feet below land surface, deep zone 75 to 160 feet below land surface) at the sites; and to construct potentiometric surfaces of the two water-yielding zones to determine the directions of groundwater flow at the sites. The presence in some wells of intermediate products of reductive dechlorination, dichloroethene and vinyl chloride, is an indication that reductive dechlorination of trichloroethene is occurring. Dissolved oxygen concentrations (less than 0.5 milligram per liter) indicate that consumption of dissolved oxygen likely had occurred in the oxygen-reducing microbial process associated with reductive dechlorination. Concentrations of nitrate and nitrite nitrogen (generally less than 2.0 and 0.06 milligrams per liter, respectively) indicate that nitrate reduction probably is not a key process in either aquifer zone. Concentrations of ferrous iron greater than 1.00 milligram per liter in the majority of wells sampled indicate that iron reduction is probable. Concentrations of sulfide less than 0.05 milligram per liter in all wells indicate that sulfate reduction probably is not a key process in either zone. The presence of methane in ground water is an indication of strongly reducing conditions that facilitate reductive dechlorination. Methane was detected in all but one well. In the shallow zone in the eastern part of the study area, ground water flowing from the northwest and south coalesces in a potentiometric trough, then moves westward and ultimately northwestward. In the western part of the study area, ground water in the shallow zone flows northwest. In the deep zone in the eastern part of the study area, ground water generally flows northwestward; and in the western part of the study area, ground water in the deep zone generally flows northward.

  18. Stability of mycotoxins during food processing.

    PubMed

    Bullerman, Lloyd B; Bianchini, Andreia

    2007-10-20

    The mycotoxins that commonly occur in cereal grains and other products are not completely destroyed during food processing operations and can contaminate finished processed foods. The mycotoxins most commonly associated with cereal grains are aflatoxins, ochratoxin A, fumonisins, deoxynivalenol and zearalenone. The various food processes that may have effects on mycotoxins include sorting, trimming, cleaning, milling, brewing, cooking, baking, frying, roasting, canning, flaking, alkaline cooking, nixtamalization, and extrusion. Most of the food processes have variable effects on mycotoxins, with those that utilize the highest temperatures having greatest effects. In general the processes reduce mycotoxin concentrations significantly, but do not eliminate them completely. However, roasting and extrusion processing show promise for lowering mycotoxin concentrations, though very high temperatures are needed to bring about much of a reduction in mycotoxin concentrations. Extrusion processing at temperatures greater than 150 degrees C are needed to give good reduction of zearalenone, moderate reduction of alfatoxins, variable to low reduction of deoxynivalenol and good reduction of fumonisins. The greatest reductions of fumonisins occur at extrusion temperatures of 160 degrees C or higher and in the presence of glucose. Extrusion of fumonisin contaminated corn grits with 10% added glucose resulted in 75-85% reduction in Fumonisin B(1) levels. Some fumonisin degredation products are formed during extrusion, including small amounts of hydrolyzed Fumonisin B(1) and N-(Carboxymethyl) - Fumonisin B(1) and somewhat higher amounts of N-(1-deoxy-d-fructos-1-yl) Fumonisin B(1) in extruded grits containing added glucose. Feeding trial toxicity tests in rats with extruded fumonisin contaminated corn grits show some reduction in toxicity of grits extruded with glucose.

  19. Modeling and Reduction With Applications to Semiconductor Processing

    DTIC Science & Technology

    1999-01-01

    smoothies ,” as they kept my energy level high without resorting to coffee (the beverage of choice, it seems, for graduate students). My advisor gave me all...with POC data, and balancing approach. . . . . . . . . . . . . . . . 312 xii LIST OF FIGURES 1.1 General state-space model reduction methodology ...reduction problem, then, is one of finding a systematic methodology within a given mathematical framework to produce an efficient or optimal trade-off of

  20. Solar Light Photocatalytic CO2 Reduction: General Considerations and Selected Bench-Mark Photocatalysts

    PubMed Central

    Neaţu, Ştefan; Maciá-Agulló, Juan Antonio; Garcia, Hermenegildo

    2014-01-01

    The reduction of carbon dioxide to useful chemicals has received a great deal of attention as an alternative to the depletion of fossil resources without altering the atmospheric CO2 balance. As the chemical reduction of CO2 is energetically uphill due to its remarkable thermodynamic stability, this process requires a significant transfer of energy. Achievements in the fields of photocatalysis during the last decade sparked increased interest in the possibility of using sunlight to reduce CO2. In this review we discuss some general features associated with the photocatalytic reduction of CO2 for the production of solar fuels, with considerations to be taken into account of the photocatalyst design, of the limitations arising from the lack of visible light response of titania, of the use of co-catalysts to overcome this shortcoming, together with several strategies that have been applied to enhance the photocatalytic efficiency of CO2 reduction. The aim is not to provide an exhaustive review of the area, but to present general aspects to be considered, and then to outline which are currently the most efficient photocatalytic systems. PMID:24670477

  1. Solar light photocatalytic CO2 reduction: general considerations and selected bench-mark photocatalysts.

    PubMed

    Neațu, Stefan; Maciá-Agulló, Juan Antonio; Garcia, Hermenegildo

    2014-03-25

    The reduction of carbon dioxide to useful chemicals has received a great deal of attention as an alternative to the depletion of fossil resources without altering the atmospheric CO2 balance. As the chemical reduction of CO2 is energetically uphill due to its remarkable thermodynamic stability, this process requires a significant transfer of energy. Achievements in the fields of photocatalysis during the last decade sparked increased interest in the possibility of using sunlight to reduce CO2. In this review we discuss some general features associated with the photocatalytic reduction of CO2 for the production of solar fuels, with considerations to be taken into account of the photocatalyst design, of the limitations arising from the lack of visible light response of titania, of the use of co-catalysts to overcome this shortcoming, together with several strategies that have been applied to enhance the photocatalytic efficiency of CO2 reduction. The aim is not to provide an exhaustive review of the area, but to present general aspects to be considered, and then to outline which are currently the most efficient photocatalytic systems.

  2. Use what you can: storage, abstraction processes, and perceptual adjustments help listeners recognize reduced forms

    PubMed Central

    Poellmann, Katja; Mitterer, Holger; McQueen, James M.

    2014-01-01

    Three eye-tracking experiments tested whether native listeners recognized reduced Dutch words better after having heard the same reduced words, or different reduced words of the same reduction type and whether familiarization with one reduction type helps listeners to deal with another reduction type. In the exposure phase, a segmental reduction group was exposed to /b/-reductions (e.g., minderij instead of binderij, “book binder”) and a syllabic reduction group was exposed to full-vowel deletions (e.g., p'raat instead of paraat, “ready”), while a control group did not hear any reductions. In the test phase, all three groups heard the same speaker producing reduced-/b/ and deleted-vowel words that were either repeated (Experiments 1 and 2) or new (Experiment 3), but that now appeared as targets in semantically neutral sentences. Word-specific learning effects were found for vowel-deletions but not for /b/-reductions. Generalization of learning to new words of the same reduction type occurred only if the exposure words showed a phonologically consistent reduction pattern (/b/-reductions). In contrast, generalization of learning to words of another reduction type occurred only if the exposure words showed a phonologically inconsistent reduction pattern (the vowel deletions; learning about them generalized to recognition of the /b/-reductions). In order to deal with reductions, listeners thus use various means. They store reduced variants (e.g., for the inconsistent vowel-deleted words) and they abstract over incoming information to build up and apply mapping rules (e.g., for the consistent /b/-reductions). Experience with inconsistent pronunciations leads to greater perceptual flexibility in dealing with other forms of reduction uttered by the same speaker than experience with consistent pronunciations. PMID:24910622

  3. Combinative Particle Size Reduction Technologies for the Production of Drug Nanocrystals

    PubMed Central

    Salazar, Jaime; Müller, Rainer H.; Möschwitzer, Jan P.

    2014-01-01

    Nanosizing is a suitable method to enhance the dissolution rate and therefore the bioavailability of poorly soluble drugs. The success of the particle size reduction processes depends on critical factors such as the employed technology, equipment, and drug physicochemical properties. High pressure homogenization and wet bead milling are standard comminution techniques that have been already employed to successfully formulate poorly soluble drugs and bring them to market. However, these techniques have limitations in their particle size reduction performance, such as long production times and the necessity of employing a micronized drug as the starting material. This review article discusses the development of combinative methods, such as the NANOEDGE, H 96, H 69, H 42, and CT technologies. These processes were developed to improve the particle size reduction effectiveness of the standard techniques. These novel technologies can combine bottom-up and/or top-down techniques in a two-step process. The combinative processes lead in general to improved particle size reduction effectiveness. Faster production of drug nanocrystals and smaller final mean particle sizes are among the main advantages. The combinative particle size reduction technologies are very useful formulation tools, and they will continue acquiring importance for the production of drug nanocrystals. PMID:26556191

  4. Symmetry Reductions of Fourth-Order Nonlinear Diffusion Equations: Lubrication Model and Some Generalizations

    NASA Astrophysics Data System (ADS)

    Gandarias, M. L.; Medina, E.

    Fourth-order nonlinear diffusion equations appear frequently in the description of physical processes, among these, the lubrication equation ut = (unuxxxx)x or the corresponding modified version ut = unuxxxx play an important role in the study of the interface movements. In this work we analyze the generalizations of the above equations given by ut = (f(u)uxxxx)x, ut = (f(u)uxxxx, and we find that if f(u) = un or f(u) = e-u the equations admit extra classical symmetries. The corresponding reductions are performed and some solutions are characterized.

  5. Processing lunar soils for oxygen and other materials

    NASA Technical Reports Server (NTRS)

    Knudsen, Christian W.; Gibson, Michael A.

    1992-01-01

    Two types of lunar materials are excellent candidates for lunar oxygen production: ilmenite and silicates such as anorthite. Both are lunar surface minable, occurring in soils, breccias, and basalts. Because silicates are considerably more abundant than ilmenite, they may be preferred as source materials. Depending on the processing method chosen for oxygen production and the feedstock material, various useful metals and bulk materials can be produced as byproducts. Available processing techniques include hydrogen reduction of ilmenite and electrochemical and chemical reductions of silicates. Processes in these categories are generally in preliminary development stages and need significant research and development support to carry them to practical deployment, particularly as a lunar-based operation. The goal of beginning lunar processing operations by 2010 requires that planning and research and development emphasize the simplest processing schemes. However, more complex schemes that now appear to present difficult technical challenges may offer more valuable metal byproducts later. While they require more time and effort to perfect, the more complex or difficult schemes may provide important processing and product improvements with which to extend and elaborate the initial lunar processing facilities. A balanced R&D program should take this into account. The following topics are discussed: (1) ilmenite--semi-continuous process; (2) ilmenite--continuous fluid-bed reduction; (3) utilization of spent ilmenite to produce bulk materials; (4) silicates--electrochemical reduction; and (5) silicates--chemical reduction.

  6. Low temperature chemical reduction of fusional sodium metasilicate nonahydrate into a honeycomb porous silicon nanostructure.

    PubMed

    Liang, Jianwen; Wei, Denghu; Lin, Ning; Zhu, Youngchun; Li, Xiaona; Zhang, Jingjing; Fan, Long; Qian, Yitai

    2014-07-04

    Honeycomb porous silicon (hp-Si) has been synthesized by a low temperature (200 °C) magnesiothermic reduction of Na2SiO3·9H2O. This process can be regarded as a general synthesis method for other silicide materials. Significantly, hp-Si features excellent electrochemical properties after graphene coating.

  7. MuLoG, or How to Apply Gaussian Denoisers to Multi-Channel SAR Speckle Reduction?

    PubMed

    Deledalle, Charles-Alban; Denis, Loic; Tabti, Sonia; Tupin, Florence

    2017-09-01

    Speckle reduction is a longstanding topic in synthetic aperture radar (SAR) imaging. Since most current and planned SAR imaging satellites operate in polarimetric, interferometric, or tomographic modes, SAR images are multi-channel and speckle reduction techniques must jointly process all channels to recover polarimetric and interferometric information. The distinctive nature of SAR signal (complex-valued, corrupted by multiplicative fluctuations) calls for the development of specialized methods for speckle reduction. Image denoising is a very active topic in image processing with a wide variety of approaches and many denoising algorithms available, almost always designed for additive Gaussian noise suppression. This paper proposes a general scheme, called MuLoG (MUlti-channel LOgarithm with Gaussian denoising), to include such Gaussian denoisers within a multi-channel SAR speckle reduction technique. A new family of speckle reduction algorithms can thus be obtained, benefiting from the ongoing progress in Gaussian denoising, and offering several speckle reduction results often displaying method-specific artifacts that can be dismissed by comparison between results.

  8. Assessing Commercial and Alternative Poultry Processing Methods using Microbiome Analyses

    USDA-ARS?s Scientific Manuscript database

    Assessing poultry processing methods/strategies has historically used culture-based methods to assess bacterial changes or reductions, both in terms of general microbial communities (e.g. total aerobic bacteria) or zoonotic pathogens of interest (e.g. Salmonella, Campylobacter). The advent of next ...

  9. The electrochemical reduction processes of solid compounds in high temperature molten salts.

    PubMed

    Xiao, Wei; Wang, Dihua

    2014-05-21

    Solid electrode processes fall in the central focus of electrochemistry due to their broad-based applications in electrochemical energy storage/conversion devices, sensors and electrochemical preparation. The electrolytic production of metals, alloys, semiconductors and oxides via the electrochemical reduction of solid compounds (especially solid oxides) in high temperature molten salts has been well demonstrated to be an effective and environmentally friendly process for refractory metal extraction, functional materials preparation as well as spent fuel reprocessing. The (electro)chemical reduction of solid compounds under cathodic polarizations generally accompanies a variety of changes at the cathode/melt electrochemical interface which result in diverse electrolytic products with different compositions, morphologies and microstructures. This report summarizes various (electro)chemical reactions taking place at the compound cathode/melt interface during the electrochemical reduction of solid compounds in molten salts, which mainly include: (1) the direct electro-deoxidation of solid oxides; (2) the deposition of the active metal together with the electrochemical reduction of solid oxides; (3) the electro-inclusion of cations from molten salts; (4) the dissolution-electrodeposition process, and (5) the electron hopping process and carbon deposition with the utilization of carbon-based anodes. The implications of the forenamed cathodic reactions on the energy efficiency, chemical compositions and microstructures of the electrolytic products are also discussed. We hope that a comprehensive understanding of the cathodic processes during the electrochemical reduction of solid compounds in molten salts could form a basis for developing a clean, energy efficient and affordable production process for advanced/engineering materials.

  10. 37 CFR 1.419 - Display of currently valid control number under the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Display of currently valid... UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES International Processing Provisions General Information § 1.419 Display of currently valid control...

  11. Optimization of Selected Remote Sensing Algorithms for Embedded NVIDIA Kepler GPU Architecture

    NASA Technical Reports Server (NTRS)

    Riha, Lubomir; Le Moigne, Jacqueline; El-Ghazawi, Tarek

    2015-01-01

    This paper evaluates the potential of embedded Graphic Processing Units in the Nvidias Tegra K1 for onboard processing. The performance is compared to a general purpose multi-core CPU and full fledge GPU accelerator. This study uses two algorithms: Wavelet Spectral Dimension Reduction of Hyperspectral Imagery and Automated Cloud-Cover Assessment (ACCA) Algorithm. Tegra K1 achieved 51 for ACCA algorithm and 20 for the dimension reduction algorithm, as compared to the performance of the high-end 8-core server Intel Xeon CPU with 13.5 times higher power consumption.

  12. Characterization of drinking water treatment for virus risk assessment.

    PubMed

    Teunis, P F M; Rutjes, S A; Westrell, T; de Roda Husman, A M

    2009-02-01

    Removal or inactivation of viruses in drinking water treatment processes can be quantified by measuring the concentrations of viruses or virus indicators in water before and after treatment. Virus reduction is then calculated from the ratio of these concentrations. Most often only the average reduction is reported. That is not sufficient when treatment efficiency must be characterized in quantitative risk assessment. We present three simple models allowing statistical analysis of series of counts before and after treatment: distribution of the ratio of concentrations, and distribution of the probability of passage for unpaired and paired water samples. Performance of these models is demonstrated for several processes (long and short term storage, coagulation/filtration, coagulation/sedimentation, slow sand filtration, membrane filtration, and ozone disinfection) using microbial indicator data from full-scale treatment processes. All three models allow estimation of the variation in (log) reduction as well as its uncertainty; the results can be easily used in risk assessment. Although they have different characteristics and are present in vastly different concentrations, different viruses and/or bacteriophages appear to show similar reductions in a particular treatment process, allowing generalization of the reduction for each process type across virus groups. The processes characterized in this paper may be used as reference for waterborne virus risk assessment, to check against location specific data, and in case no such data are available, to use as defaults.

  13. GUIs in the MIDAS environment

    NASA Technical Reports Server (NTRS)

    Ballester, P.

    1992-01-01

    MIDAS (Munich Image Data Analysis System) is the image processing system developed at ESO for astronomical data reduction. MIDAS is used for off-line data reduction at ESO and many astronomical institutes all over Europe. In addition to a set of general commands, enabling to process and analyze images, catalogs, graphics and tables, MIDAS includes specialized packages dedicated to astronomical applications or to specific ESO instruments. Several graphical interfaces are available in the MIDAS environment: XHelp provides an interactive help facility, and XLong and XEchelle enable data reduction of long-slip and echelle spectra. GUI builders facilitate the development of interfaces. All ESO interfaces comply to the ESO User Interfaces Common Conventions which secures an identical look and feel for telescope operations, data analysis, and archives.

  14. Algorithmic framework for group analysis of differential equations and its application to generalized Zakharov-Kuznetsov equations

    NASA Astrophysics Data System (ADS)

    Huang, Ding-jiang; Ivanova, Nataliya M.

    2016-02-01

    In this paper, we explain in more details the modern treatment of the problem of group classification of (systems of) partial differential equations (PDEs) from the algorithmic point of view. More precisely, we revise the classical Lie algorithm of construction of symmetries of differential equations, describe the group classification algorithm and discuss the process of reduction of (systems of) PDEs to (systems of) equations with smaller number of independent variables in order to construct invariant solutions. The group classification algorithm and reduction process are illustrated by the example of the generalized Zakharov-Kuznetsov (GZK) equations of form ut +(F (u)) xxx +(G (u)) xyy +(H (u)) x = 0. As a result, a complete group classification of the GZK equations is performed and a number of new interesting nonlinear invariant models which have non-trivial invariance algebras are obtained. Lie symmetry reductions and exact solutions for two important invariant models, i.e., the classical and modified Zakharov-Kuznetsov equations, are constructed. The algorithmic framework for group analysis of differential equations presented in this paper can also be applied to other nonlinear PDEs.

  15. Simulation of aerobic and anaerobic biodegradation processes at a crude oil spill site

    USGS Publications Warehouse

    Essaid, Hedeff I.; Bekins, Barbara A.; Godsy, E. Michael; Warren, Ean; Baedecker, Mary Jo; Cozzarelli, Isabelle M.

    1995-01-01

    A two-dimensional, multispecies reactive solute transport model with sequential aerobic and anaerobic degradation processes was developed and tested. The model was used to study the field-scale solute transport and degradation processes at the Bemidji, Minnesota, crude oil spill site. The simulations included the biodegradation of volatile and nonvolatile fractions of dissolved organic carbon by aerobic processes, manganese and iron reduction, and methanogenesis. Model parameter estimates were constrained by published Monod kinetic parameters, theoretical yield estimates, and field biomass measurements. Despite the considerable uncertainty in the model parameter estimates, results of simulations reproduced the general features of the observed groundwater plume and the measured bacterial concentrations. In the simulation, 46% of the total dissolved organic carbon (TDOC) introduced into the aquifer was degraded. Aerobic degradation accounted for 40% of the TDOC degraded. Anaerobic processes accounted for the remaining 60% of degradation of TDOC: 5% by Mn reduction, 19% by Fe reduction, and 36% by methanogenesis. Thus anaerobic processes account for more than half of the removal of DOC at this site.

  16. Generation of TiII Alkyne Trimerization Catalysts in the Absence of Strong Metal Reductants

    PubMed Central

    See, Xin Yi; Beaumier, Evan P.; Davis-Gilbert, Zachary W.; Dunn, Peter L.; Larsen, Jacob A.; Pearce, Adam J.; Wheeler, T. Alex; Tonks, Ian A.

    2017-01-01

    Low-valent TiII species have typically been synthesized by the reaction of TiIV halides with strong metal reductants. Herein we report that TiII species can be generated simply by reacting TiIV imido complexes with 2 equiv of alkyne, yielding a metallacycle that can reductively eliminate pyrrole while liberating TiII. In order to probe the generality of this process, TiII-catalyzed alkyne trimerization reactions were carried out with a diverse range of TiIV precatalysts. PMID:28690352

  17. Evaluation of a biological wastewater treatment system combining an OSA process with ultrasound for sludge reduction.

    PubMed

    Romero-Pareja, P M; Aragon, C A; Quiroga, J M; Coello, M D

    2017-05-01

    Sludge production is an undesirable by-product of biological wastewater treatment. The oxic-settling-anaerobic (OSA) process constitutes one of the most promising techniques for reducing the sludge produced at the treatment plant without negative consequences for its overall performance. In the present study, the OSA process is applied in combination with ultrasound treatment, a lysis technique, in a lab-scale wastewater treatment plant to assess whether sludge reduction is enhanced as a result of mechanical treatment. Reported sludge reductions of 45.72% and 78.56% were obtained for the two regimes of combined treatment tested in this study during two respective stages: UO1 and UO2. During the UO1 stage, the general performance and nutrient removal improved, obtaining 47.28% TN removal versus 21.95% in the conventional stage. However, the performance of the system was seriously damaged during the UO2 stage. Increases in dehydrogenase and protease activities were observed during both stages. The advantages of the combined process are not necessarily economic, but operational, as US treatment acts as contributing factor in the OSA process, inducing mechanisms that lead to sludge reduction in the OSA process and improving performance parameters. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. Youpi: YOUr processing PIpeline

    NASA Astrophysics Data System (ADS)

    Monnerville, Mathias; Sémah, Gregory

    2012-03-01

    Youpi is a portable, easy to use web application providing high level functionalities to perform data reduction on scientific FITS images. Built on top of various open source reduction tools released to the community by TERAPIX (http://terapix.iap.fr), Youpi can help organize data, manage processing jobs on a computer cluster in real time (using Condor) and facilitate teamwork by allowing fine-grain sharing of results and data. Youpi is modular and comes with plugins which perform, from within a browser, various processing tasks such as evaluating the quality of incoming images (using the QualityFITS software package), computing astrometric and photometric solutions (using SCAMP), resampling and co-adding FITS images (using SWarp) and extracting sources and building source catalogues from astronomical images (using SExtractor). Youpi is useful for small to medium-sized data reduction projects; it is free and is published under the GNU General Public License.

  19. Parallelizing Compiler Framework and API for Power Reduction and Software Productivity of Real-Time Heterogeneous Multicores

    NASA Astrophysics Data System (ADS)

    Hayashi, Akihiro; Wada, Yasutaka; Watanabe, Takeshi; Sekiguchi, Takeshi; Mase, Masayoshi; Shirako, Jun; Kimura, Keiji; Kasahara, Hironori

    Heterogeneous multicores have been attracting much attention to attain high performance keeping power consumption low in wide spread of areas. However, heterogeneous multicores force programmers very difficult programming. The long application program development period lowers product competitiveness. In order to overcome such a situation, this paper proposes a compilation framework which bridges a gap between programmers and heterogeneous multicores. In particular, this paper describes the compilation framework based on OSCAR compiler. It realizes coarse grain task parallel processing, data transfer using a DMA controller, power reduction control from user programs with DVFS and clock gating on various heterogeneous multicores from different vendors. This paper also evaluates processing performance and the power reduction by the proposed framework on a newly developed 15 core heterogeneous multicore chip named RP-X integrating 8 general purpose processor cores and 3 types of accelerator cores which was developed by Renesas Electronics, Hitachi, Tokyo Institute of Technology and Waseda University. The framework attains speedups up to 32x for an optical flow program with eight general purpose processor cores and four DRP(Dynamically Reconfigurable Processor) accelerator cores against sequential execution by a single processor core and 80% of power reduction for the real-time AAC encoding.

  20. Value Driven Information Processing and Fusion

    DTIC Science & Technology

    2016-03-01

    consensus approach allows a decentralized approach to achieve the optimal error exponent of the centralized counterpart, a conclusion that is signifi...SECURITY CLASSIFICATION OF: The objective of the project is to develop a general framework for value driven decentralized information processing...including: optimal data reduction in a network setting for decentralized inference with quantization constraint; interactive fusion that allows queries and

  1. Modeling the dynamics of multipartite quantum systems created departing from two-level systems using general local and non-local interactions

    NASA Astrophysics Data System (ADS)

    Delgado, Francisco

    2017-12-01

    Quantum information is an emergent area merging physics, mathematics, computer science and engineering. To reach its technological goals, it is requiring adequate approaches to understand how to combine physical restrictions, computational approaches and technological requirements to get functional universal quantum information processing. This work presents the modeling and the analysis of certain general type of Hamiltonian representing several physical systems used in quantum information and establishing a dynamics reduction in a natural grammar for bipartite processing based on entangled states.

  2. MYRaf: A new Approach with IRAF for Astronomical Photometric Reduction

    NASA Astrophysics Data System (ADS)

    Kilic, Y.; Shameoni Niaei, M.; Özeren, F. F.; Yesilyaprak, C.

    2016-12-01

    In this study, the design and some developments of MYRaf software for astronomical photometric reduction are presented. MYRaf software is an easy to use, reliable, and has a fast IRAF aperture photometry GUI tools. MYRaf software is an important step for the automated software process of robotic telescopes, and uses IRAF, PyRAF, matplotlib, ginga, alipy, and Sextractor with the general-purpose and high-level programming language Python and uses the QT framework.

  3. ALTERNATIVE TO CHROME ETCHING PROCESSES FOR METALS

    EPA Science Inventory

    Several industries, including the National Center for Manufacturing Science have initiated programs for chrome abatement. The programs, however, generally focus on chrome reduction by use of existing technologies and do not address the elimination of chrome in pretreatment proces...

  4. Reduction of verotoxigenic Escherichia coli in production of fermented sausages.

    PubMed

    Holck, Askild L; Axelsson, Lars; Rode, Tone Mari; Høy, Martin; Måge, Ingrid; Alvseike, Ole; L'abée-Lund, Trine M; Omer, Mohamed K; Granum, Per Einar; Heir, Even

    2011-11-01

    After a number of foodborne outbreaks of verotoxigenic Escherichia coli involving fermented sausages, some countries have imposed regulations on sausage production. For example, the US Food Safety and Inspection Service requires a 5 log(10) reduction of E. coli in fermented products. Such regulations have led to a number of studies on the inactivation of E. coli in fermented sausages by changing processing and post-processing conditions. Several factors influence the survival of E. coli such as pre-treatment of the meat, amount of NaCl, nitrite and lactic acid, water activity, pH, choice of starter cultures and addition of antimicrobial compounds. Also process variables like fermentation temperature and storage time play important roles. Though a large variety of different production processes of sausages exist, generally the reduction of E. coli caused by production is in the range 1-2 log(10). In many cases this may not be enough to ensure microbial food safety. By optimising ingredients and process parameters it is possible to increase E. coli reduction to some extent, but in some cases still other post process treatments may be required. Such treatments may be storage at ambient temperatures, specific heat treatments, high pressure processing or irradiation. HACCP analyses have identified the quality of the raw materials, low temperature in the batter when preparing the sausages and a rapid pH drop during fermentation as critical control points in sausage production. This review summarises the literature on the reduction verotoxigenic E. coli in production of fermented sausages. Copyright © 2011 Elsevier Ltd. All rights reserved.

  5. Organizational Information-Seeking in the Digital Era: A Model of New Media Use, Uncertainty Reduction, Identification and Culture

    ERIC Educational Resources Information Center

    Ju, Ran

    2013-01-01

    This dissertation examines the role of new media in individuals' organizational socialization process across cultures. First, this study has explored individuals' use of new media in their organizational socialization process in two countries, China and the United States, to gain a general understanding of the usage patterns. Second, this study…

  6. General Purpose Graphics Processing Unit Based High-Rate Rice Decompression and Reed-Solomon Decoding

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Loughry, Thomas A.

    As the volume of data acquired by space-based sensors increases, mission data compression/decompression and forward error correction code processing performance must likewise scale. This competency development effort was explored using the General Purpose Graphics Processing Unit (GPGPU) to accomplish high-rate Rice Decompression and high-rate Reed-Solomon (RS) decoding at the satellite mission ground station. Each algorithm was implemented and benchmarked on a single GPGPU. Distributed processing across one to four GPGPUs was also investigated. The results show that the GPGPU has considerable potential for performing satellite communication Data Signal Processing, with three times or better performance improvements and up to tenmore » times reduction in cost over custom hardware, at least in the case of Rice Decompression and Reed-Solomon Decoding.« less

  7. High-Speed On-Board Data Processing for Science Instruments

    NASA Technical Reports Server (NTRS)

    Beyon, Jeffrey Y.; Ng, Tak-Kwong; Lin, Bing; Hu, Yongxiang; Harrison, Wallace

    2014-01-01

    A new development of on-board data processing platform has been in progress at NASA Langley Research Center since April, 2012, and the overall review of such work is presented in this paper. The project is called High-Speed On-Board Data Processing for Science Instruments (HOPS) and focuses on a high-speed scalable data processing platform for three particular National Research Council's Decadal Survey missions such as Active Sensing of CO2 Emissions over Nights, Days, and Seasons (ASCENDS), Aerosol-Cloud-Ecosystems (ACE), and Doppler Aerosol Wind Lidar (DAWN) 3-D Winds. HOPS utilizes advanced general purpose computing with Field Programmable Gate Array (FPGA) based algorithm implementation techniques. The significance of HOPS is to enable high speed on-board data processing for current and future science missions with its reconfigurable and scalable data processing platform. A single HOPS processing board is expected to provide approximately 66 times faster data processing speed for ASCENDS, more than 70% reduction in both power and weight, and about two orders of cost reduction compared to the state-of-the-art (SOA) on-board data processing system. Such benchmark predictions are based on the data when HOPS was originally proposed in August, 2011. The details of these improvement measures are also presented. The two facets of HOPS development are identifying the most computationally intensive algorithm segments of each mission and implementing them in a FPGA-based data processing board. A general introduction of such facets is also the purpose of this paper.

  8. Is dissonance reduction a special case of fluid compensation? Evidence that dissonant cognitions cause compensatory affirmation and abstraction.

    PubMed

    Randles, Daniel; Inzlicht, Michael; Proulx, Travis; Tullett, Alexa M; Heine, Steven J

    2015-05-01

    Cognitive dissonance theory shares much in common with other perspectives that address anomalies, uncertainty, and general expectancy violations. This has led some theorists to argue that these theories represent overlapping psychological processes. If responding to dissonance and uncertainty occurs through a common psychological process, one should expect that the behavioral outcomes of feeling uncertain would also apply to feelings of dissonance, and vice versa. One specific prediction from the meaning maintenance model would be that cognitive dissonance, like other expectancy violations, should lead to the affirmation of unrelated beliefs, or the abstraction of unrelated schemas when the dissonant event cannot be easily accommodated. This article presents 4 studies (N = 1124) demonstrating that the classic induced-compliance dissonance paradigm can lead not only to a change of attitudes (dissonance reduction), but also to (a) an increased reported belief in God (Study 2), (b) a desire to punish norm-violators (Study 1 and 3), (c) a motivation to detect patterns amid noise (Study 3), and (d) polarizing support of public policies among those already biased toward a particular side (Study 4). These results are congruent with theories that propose content-general fluid compensation following the experience of anomaly, a finding not predicted by dissonance theory. The results suggest that dissonance reduction behaviors may share psychological processes described by other theories addressing violations of expectations. (c) 2015 APA, all rights reserved).

  9. Conceptual design of a data reduction system

    NASA Technical Reports Server (NTRS)

    1983-01-01

    A telemetry data processing system was defined of the Data Reduction. Data reduction activities in support of the developmental flights of the Space Shuttle were used as references against which requirements are assessed in general terms. A conceptual system design believed to offer significant throughput for the anticipated types of data reduction activities is presented. The design identifies the use of a large, intermediate data store as a key element in a complex of high speed, single purpose processors, each of which performs predesignated, repetitive operations on either raw or partially processed data. The recommended approach to implement the design concept is to adopt an established interface standard and rely heavily on mature or promising technologies which are considered main stream of the integrated circuit industry. The design system concept, is believed to be implementable without reliance on exotic devices and/or operational procedures. Numerical methods were employed to examine the feasibility of digital discrimination of FDM composite signals, and of eliminating line frequency noises in data measurements.

  10. Assessment of the GHG Reduction Potential from Energy Crops Using a Combined LCA and Biogeochemical Process Models: A Review

    PubMed Central

    Jiang, Dong; Hao, Mengmeng; Wang, Qiao; Huang, Yaohuan; Fu, Xinyu

    2014-01-01

    The main purpose for developing biofuel is to reduce GHG (greenhouse gas) emissions, but the comprehensive environmental impact of such fuels is not clear. Life cycle analysis (LCA), as a complete comprehensive analysis method, has been widely used in bioenergy assessment studies. Great efforts have been directed toward establishing an efficient method for comprehensively estimating the greenhouse gas (GHG) emission reduction potential from the large-scale cultivation of energy plants by combining LCA with ecosystem/biogeochemical process models. LCA presents a general framework for evaluating the energy consumption and GHG emission from energy crop planting, yield acquisition, production, product use, and postprocessing. Meanwhile, ecosystem/biogeochemical process models are adopted to simulate the fluxes and storage of energy, water, carbon, and nitrogen in the soil-plant (energy crops) soil continuum. Although clear progress has been made in recent years, some problems still exist in current studies and should be addressed. This paper reviews the state-of-the-art method for estimating GHG emission reduction through developing energy crops and introduces in detail a new approach for assessing GHG emission reduction by combining LCA with biogeochemical process models. The main achievements of this study along with the problems in current studies are described and discussed. PMID:25045736

  11. Chem I Supplement: Chemistry of Steel Making.

    ERIC Educational Resources Information Center

    Sellers, Neal

    1980-01-01

    Provides information about the chemistry of steel making applicable to teaching secondary school science. Generalized chemical reactions describe the manufacture of steel from iron ore. Also discussed are raw materials, processing choices, and how various furnaces (blast, direct reduction, open hearth, basic oxygen, electric) work. (CS)

  12. Assessment of critical-fluid extractions in the process industries

    NASA Technical Reports Server (NTRS)

    1982-01-01

    The potential for critical-fluid extraction as a separation process for improving the productive use of energy in the process industries is assessed. Critical-fluid extraction involves the use of fluids, normally gaseous at ambient conditions, as extraction solvents at temperatures and pressures around the critical point. Equilibrium and kinetic properties in this regime are very favorable for solvent applications, and generally allow major reductions in the energy requirements for separating and purifying chemical component of a mixture.

  13. Effects of food processing on pesticide residues in fruits and vegetables: a meta-analysis approach.

    PubMed

    Keikotlhaile, B M; Spanoghe, P; Steurbaut, W

    2010-01-01

    Pesticides are widely used in food production to increase food security despite the fact that they can have negative health effects on consumers. Pesticide residues have been found in various fruits and vegetables; both raw and processed. One of the most common routes of pesticide exposure in consumers is via food consumption. Most foods are consumed after passing through various culinary and processing treatments. A few literature reviews have indicated the general trend of reduction or concentration of pesticide residues by certain methods of food processing for a particular active ingredient. However, no review has focused on combining the obtained results from different studies on different active ingredients with differences in experimental designs, analysts and analysis equipment. In this paper, we present a meta-analysis of response ratios as a possible method of combining and quantifying effects of food processing on pesticide residue levels. Reduction of residue levels was indicated by blanching, boiling, canning, frying, juicing, peeling and washing of fruits and vegetables with an average response ratio ranging from 0.10 to 0.82. Baking, boiling, canning and juicing indicated both reduction and increases for the 95% and 99.5% confidence intervals. Copyright 2009 Elsevier Ltd. All rights reserved.

  14. Endogenous System Microbes as Treatment Process ...

    EPA Pesticide Factsheets

    Monitoring the efficacy of treatment strategies to remove pathogens in decentralized systems remains a challenge. Evaluating log reduction targets by measuring pathogen levels is hampered by their sporadic and low occurrence rates. Fecal indicator bacteria are used in centralized systems to indicate the presence of fecal pathogens, but are ineffective decentralized treatment process indicators as they generally occur at levels too low to assess log reduction targets. System challenge testing by spiking with high loads of fecal indicator organisms, like MS2 coliphage, has limitations, especially for large systems. Microbes that are endogenous to the decentralized system, occur in high abundances and mimic removal rates of bacterial, viral and/or parasitic protozoan pathogens during treatment could serve as alternative treatment process indicators to verify log reduction targets. To identify abundant microbes in wastewater, the bacterial and viral communities were examined using deep sequencing. Building infrastructure-associated bacteria, like Zoogloea, were observed as dominant members of the bacterial community in graywater. In blackwater, bacteriophage of the order Caudovirales constituted the majority of contiguous sequences from the viral community. This study identifies candidate treatment process indicators in decentralized systems that could be used to verify log removal during treatment. The association of the presence of treatment process indic

  15. Reduction of verotoxigenic Escherichia coli by process and recipe optimisation in dry-fermented sausages.

    PubMed

    Heir, E; Holck, A L; Omer, M K; Alvseike, O; Høy, M; Måge, I; Axelsson, L

    2010-07-15

    Outbreaks of verotoxigenic Escherichia coli (VTEC) linked to dry-fermented sausages (DFSs) have emphasized the need for DFS manufacturers to introduce measures to obtain enhanced safety and still maintain the sensory qualities of their products. To our knowledge no data have yet been reported on non-O157:H7 VTEC survival in DFS. Here, the importance of recipe and process variables on VTEC (O157:H7 and O103:H25) reductions in two types of DFS, morr and salami, was determined through three statistically designed experiments. Linear regression and ANOVA analyses showed that no single variable had a dominant effect on VTEC reductions. High levels of NaCl, NaNO(2), glucose (low pH) and fermentation temperature gave enhanced VTEC reduction, while high fat and large casing diameter (a(w)) gave the opposite effect. Interaction effects were small. The process and recipe variables showed similar effects in morr and salami. In general, recipes combining high batter levels of salt (NaCl and NaNO(2)) and glucose along with high fermentation temperature that gave DFS with low final pH and a(w), provided approximately 3 log(10) reductions compared to approximately 1.5 log(10) reductions obtained for standard recipe DFS. Storage at 4 degrees C for 2 months provided log(10) 0.33-0.95 additional VTEC reductions and were only marginally affected by recipe type. Sensory tests revealed only small differences between the various recipes of morr and salami. By optimisation of recipe and process parameters, it is possible to obtain increased microbial safety of DFS while maintaining the sensory qualities of the sausages. 2010 Elsevier B.V. All rights reserved.

  16. Advanced air revitalization system modeling and testing

    NASA Technical Reports Server (NTRS)

    Dall-Baumann, Liese; Jeng, Frank; Christian, Steve; Edeer, Marybeth; Lin, Chin

    1990-01-01

    To support manned lunar and Martian exploration, an extensive evaluation of air revitalization subsystems (ARS) is being conducted. The major operations under study include carbon dioxide removal and reduction; oxygen and nitrogen production, storage, and distribution; humidity and temperature control; and trace contaminant control. A comprehensive analysis program based on a generalized block flow model was developed to facilitate the evaluation of various processes and their interaction. ASPEN PLUS was used in modelling carbon dioxide removal and reduction. Several life support test stands were developed to test new and existing technologies for their potential applicability in space. The goal was to identify processes which use compact, lightweight equipment and maximize the recovery of oxygen and water. The carbon dioxide removal test stands include solid amine/vacuum desorption (SAVD), regenerative silver oxide chemisorption, and electrochemical carbon dioxide concentration (EDC). Membrane-based carbon dioxide removal and humidity control, catalytic reduction of carbon dioxide, and catalytic oxidation of trace contaminants were also investigated.

  17. Prescribed burning in southwestern ponderosa pine

    Treesearch

    Stephen S Sackett; Sally M Haase; Michael G Harrington

    1996-01-01

    Prescribed burning is an effective way of restoring the fire process to ponderosa pine (Pinus ponderosa Dougl. ex Laws.) ecosystems of the Southwest. If used judiciously, fire can provide valuable effects for hazard reduction, natural regeneration, thinning, vegetation revitalization, and in general, better forest health. Relatively short burning...

  18. 40 CFR 98.173 - Calculating GHG emissions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... associated requirements for Tier 4 in subpart C of this part (General Stationary Fuel Combustion Sources). (b..., dry basis (% CO2). Q = Hourly stack gas volumetric flow rate (scfh). %H2O = Hourly moisture percentage... reduction furnace are vented through the same stack as any combustion unit or process equipment that reports...

  19. 40 CFR 410.33 - Effluent limitations representing the degree of effluent reduction attainable by the application...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... achievable (BAT). 410.33 Section 410.33 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... application of the best available technology economically achievable (BAT). Except as provided in 40 CFR 125... best available technology economically achievable (BAT): General Processing Pollutant or pollutant...

  20. 40 CFR 410.33 - Effluent limitations representing the degree of effluent reduction attainable by the application...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... achievable (BAT). 410.33 Section 410.33 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... application of the best available technology economically achievable (BAT). Except as provided in 40 CFR 125... best available technology economically achievable (BAT): General Processing Pollutant or pollutant...

  1. 40 CFR 410.33 - Effluent limitations representing the degree of effluent reduction attainable by the application...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... achievable (BAT). 410.33 Section 410.33 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... application of the best available technology economically achievable (BAT). Except as provided in 40 CFR 125... best available technology economically achievable (BAT): General Processing Pollutant or pollutant...

  2. 40 CFR 410.33 - Effluent limitations representing the degree of effluent reduction attainable by the application...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... achievable (BAT). 410.33 Section 410.33 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... application of the best available technology economically achievable (BAT). Except as provided in 40 CFR 125... best available technology economically achievable (BAT): General Processing Pollutant or pollutant...

  3. 30 CFR 203.89 - What is in a cost report?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... estimates, or analogous projects. These costs cover: (1) Oil or gas tariffs from pipeline or tankerage; (2) Trunkline and tieback lines; and (3) Gas plant processing for natural gas liquids. (e) Abandonment costs... INTERIOR MINERALS REVENUE MANAGEMENT RELIEF OR REDUCTION IN ROYALTY RATES OCS Oil, Gas, and Sulfur General...

  4. Achieving performance breakthroughs in an HMO business process through quality planning.

    PubMed

    Hanan, K B

    1993-01-01

    Kaiser Permanente's Georgia Region commissioned a quality planning team to design a new process to improve payments to its suppliers and vendors. The result of the team's effort was a 73 percent reduction in cycle time. This team's experiences point to the advantages of process redesign as a quality planning model, as well as some general guidelines for its most effective use in teams. If quality planning project teams are carefully configured, sufficiently expert in the existing process, and properly supported by management, organizations can achieve potentially dramatic improvements in process performance using this approach.

  5. Eye Movements while Reading Biased Homographs: Effects of Prior Encounter and Biasing Context on Reducing the Subordinate Bias Effect

    PubMed Central

    Leinenger, Mallorie; Rayner, Keith

    2013-01-01

    Readers experience processing difficulties when reading biased homographs preceded by subordinate-biasing contexts. Attempts to overcome this processing deficit have often failed to reduce the subordinate bias effect (SBE). In the present studies, we examined the processing of biased homographs preceded by single-sentence, subordinate-biasing contexts, and varied whether this preceding context contained a prior instance of the homograph or a control word/phrase. Having previously encountered the homograph earlier in the sentence reduced the SBE for the subsequent encounter, while simply instantiating the subordinate meaning produced processing difficulty. We compared these reductions in reading times to differences in processing time between dominant-biased repeated and non-repeated conditions in order to verify that the reductions observed in the subordinate cases did not simply reflect a general repetition benefit. Our results indicate that a strong, subordinate-biasing context can interact during lexical access to overcome the activation from meaning frequency and reduce the SBE during reading. PMID:24073328

  6. Static Thermochemical Model of COREX Melter Gasifier

    NASA Astrophysics Data System (ADS)

    Srishilan, C.; Shukla, Ajay Kumar

    2018-02-01

    COREX is one of the commercial smelting reduction processes. It uses the finer size ore and semi-soft coal instead of metallurgical coke to produce hot metal from iron ore. The use of top gas with high calorific value as a by-product export gas makes the process economical and green. The predictive thermochemical model of the COREX process presented here enables rapid computation of process parameters such as (1) required amount of ore, coal, and flux; (2) amount of slag and gas generated; and (3) gas compositions (based on the raw material and desired hot metal quality). The model helps in predicting the variations in process parameters with respect to the (1) degree of metallization and (2) post-combustion ratio for given raw material conditions. In general reduction in coal, flux, and oxygen, the requirement is concomitant with an increase in the degree of metallization and post-combustion ratio. The model reported here has been benchmarked using industrial data obtained from the JSW Steel Plant, India.

  7. Enhanced viscous flow drag reduction using acoustic excitation

    NASA Technical Reports Server (NTRS)

    Nagel, Robert T.

    1987-01-01

    Proper acoustic excitation of a single large-eddy break-up device can increase the resulting drag reduction and, after approximately 40 to 50 delta downstream, provide net drag reduction. Precise optimization of the input time delay, amplitude and response threshold is difficult but possible to achieve. Drag reduction is improved with optimized conditions. The possibility of optimized processing strongly suggests a mechanism which involves interaction of the acoustic waves and large eddies at the trailing edge of the large eddy break-up device. Although the mechanism for spreading of this phenomenon is unknown, it is apparent that the drag reduction effect does tend to spread spanwise as the flow convects downstream. The phenomenon is not unique to a particular blade configuration or flow velocity, although all data have been obtained at relatively low Reynolds numbers. The general repeatibility of the results for small configuration changes serves as verification of the phenomenon.

  8. Engine dynamic analysis with general nonlinear finite element codes

    NASA Technical Reports Server (NTRS)

    Adams, M. L.; Padovan, J.; Fertis, D. G.

    1991-01-01

    A general engine dynamic analysis as a standard design study computational tool is described for the prediction and understanding of complex engine dynamic behavior. Improved definition of engine dynamic response provides valuable information and insights leading to reduced maintenance and overhaul costs on existing engine configurations. Application of advanced engine dynamic simulation methods provides a considerable cost reduction in the development of new engine designs by eliminating some of the trial and error process done with engine hardware development.

  9. A class of generalized Ginzburg-Landau equations with random switching

    NASA Astrophysics Data System (ADS)

    Wu, Zheng; Yin, George; Lei, Dongxia

    2018-09-01

    This paper focuses on a class of generalized Ginzburg-Landau equations with random switching. In our formulation, the nonlinear term is allowed to have higher polynomial growth rate than the usual cubic polynomials. The random switching is modeled by a continuous-time Markov chain with a finite state space. First, an explicit solution is obtained. Then properties such as stochastic-ultimate boundedness and permanence of the solution processes are investigated. Finally, two-time-scale models are examined leading to a reduction of complexity.

  10. Generalized Bell states map physical systems’ quantum evolution into a grammar for quantum information processing

    NASA Astrophysics Data System (ADS)

    Delgado, Francisco

    2017-12-01

    Quantum information processing should be generated through control of quantum evolution for physical systems being used as resources, such as superconducting circuits, spinspin couplings in ions and artificial anyons in electronic gases. They have a quantum dynamics which should be translated into more natural languages for quantum information processing. On this terrain, this language should let to establish manipulation operations on the associated quantum information states as classical information processing does. This work shows how a kind of processing operations can be settled and implemented for quantum states design and quantum processing for systems fulfilling a SU(2) reduction in their dynamics.

  11. Integrating sodium reduction strategies in the procurement process and contracting of food venues in the County of Los Angeles government, 2010-2012.

    PubMed

    Cummings, Patricia L; Kuo, Tony; Gase, Lauren N; Mugavero, Kristy

    2014-01-01

    Since sodium is ubiquitous in the food supply, recent approaches to sodium reduction have focused on increasing the availability of lower-sodium products through system-level and environmental changes. This article reviews integrated efforts by the Los Angeles County Sodium Reduction Initiative to implement these strategies at food venues in the County of Los Angeles government. The review used mixed methods, including a scan of the literature, key informant interviews, and lessons learned during 2010-2012 to assess program progress. Leveraging technical expertise and shared resources, the initiative strategically incorporated sodium reduction strategies into the overall work plan of a multipartnership food procurement program in Los Angeles County. To date, 3 County departments have incorporated new or updated nutrition requirements that included sodium limits and other strategies. The strategic coupling of sodium reduction to food procurement and general health promotion allowed for simultaneous advancement and acceleration of the County's sodium reduction agenda.

  12. Integrating Sodium Reduction Strategies in the Procurement Process and Contracting of Food Venues in the County of Los Angeles Government, 2010–2012

    PubMed Central

    Cummings, Patricia L.; Kuo, Tony; Gase, Lauren N.; Mugavero, Kristy

    2015-01-01

    Since sodium is ubiquitous in the food supply, recent approaches to sodium reduction have focused on increasing the availability of lower-sodium products through system-level and environmental changes. This article reviews integrated efforts by the Los Angeles County Sodium Reduction Initiative to implement these strategies at food venues in the County of Los Angeles government. The review used mixed methods, including a scan of the literature, key informant interviews, and lessons learned during 2010–2012 to assess program progress. Leveraging technical expertise and shared resources, the initiative strategically incorporated sodium reduction strategies into the overall work plan of a multipartnership food procurement program in Los Angeles County. To date, 3 County departments have incorporated new or updated nutrition requirements that included sodium limits and other strategies. The strategic coupling of sodium reduction to food procurement and general health promotion allowed for simultaneous advancement and acceleration of the County’s sodium reduction agenda. PMID:24322811

  13. Optimal linear and nonlinear feature extraction based on the minimization of the increased risk of misclassification. [Bayes theorem - statistical analysis/data processing

    NASA Technical Reports Server (NTRS)

    Defigueiredo, R. J. P.

    1974-01-01

    General classes of nonlinear and linear transformations were investigated for the reduction of the dimensionality of the classification (feature) space so that, for a prescribed dimension m of this space, the increase of the misclassification risk is minimized.

  14. Lifestyle, Body Composition, and Physical Fitness Changes in Hungarian School Boys (1975-2005)

    ERIC Educational Resources Information Center

    Photiou, A.; Anning, J. H.; Meszaros, J.; Vajda, I.; Meszaros, Z.; Sziva, A.; Prokai, A.; Ng, N.

    2008-01-01

    General socioeconomic conditions as well as the physical environment have undergone remarkable changes in Hungary during the past 30 years. Unfortunately, these positive processes have resulted in a reduction of habitual physical activity along with unfavorable changes in dietary habits. Therefore, the purpose of the present study was to compare…

  15. Defining Usability Heuristics for Adoption and Efficiency of an Electronic Workflow Document Management System

    ERIC Educational Resources Information Center

    Fuentes, Steven

    2017-01-01

    Usability heuristics have been established for different uses and applications as general guidelines for user interfaces. These can affect the implementation of industry solutions and play a significant role regarding cost reduction and process efficiency. The area of electronic workflow document management (EWDM) solutions, also known as…

  16. 30 CFR 203.89 - What is in a cost report?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... projects. These costs cover: (1) Oil or gas tariffs from pipeline or tankerage; (2) Trunkline and tieback lines; and (3) Gas plant processing for natural gas liquids. (e) Abandonment costs, based on historical... REVENUE MANAGEMENT RELIEF OR REDUCTION IN ROYALTY RATES OCS Oil, Gas, and Sulfur General § 203.89 What is...

  17. 30 CFR 203.89 - What is in a cost report?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... projects. These costs cover: (1) Oil or gas tariffs from pipeline or tankerage; (2) Trunkline and tieback lines; and (3) Gas plant processing for natural gas liquids. (e) Abandonment costs, based on historical... RELIEF OR REDUCTION IN ROYALTY RATES OCS Oil, Gas, and Sulfur General Required Reports § 203.89 What is...

  18. 30 CFR 203.89 - What is in a cost report?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... projects. These costs cover: (1) Oil or gas tariffs from pipeline or tankerage; (2) Trunkline and tieback lines; and (3) Gas plant processing for natural gas liquids. (e) Abandonment costs, based on historical... REVENUE MANAGEMENT RELIEF OR REDUCTION IN ROYALTY RATES OCS Oil, Gas, and Sulfur General § 203.89 What is...

  19. 30 CFR 203.89 - What is in a cost report?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... projects. These costs cover: (1) Oil or gas tariffs from pipeline or tankerage; (2) Trunkline and tieback lines; and (3) Gas plant processing for natural gas liquids. (e) Abandonment costs, based on historical... REVENUE MANAGEMENT RELIEF OR REDUCTION IN ROYALTY RATES OCS Oil, Gas, and Sulfur General § 203.89 What is...

  20. High Temperature Modification of SNCR Technology and its Impact on NOx Removal Process

    NASA Astrophysics Data System (ADS)

    Blejchař, Tomáš; Konvička, Jaroslav; von der Heide, Bernd; Malý, Rostislav; Maier, Miloš

    2018-06-01

    SNCR (Selective non-catalytic reduction) Technology is currently being used to reach the emission limit for nitrogen oxides at fossil fuel fired power plant and/or heating plant and optimum temperature for SNCR process is in range 850 - 1050°C. Modified SNCR technology is able to reach reduction 60% of nitrogen oxides at temperature up to 1250°C. So the technology can also be installed where the flue gas temperature is too high in combustion chamber. Modified SNCR was tested using generally known SNCR chemistry implemented in CFD (Computation fluid dynamics) code. CFD model was focused on detail simulation of reagent injection and influence of flue gas temperature. Than CFD simulation was compared with operating data of boiler where the modified SNCR technology is installed. By comparing the experiment results with the model, the effect on nitrous oxides removal process and temperature of flue gas at the injection region.

  1. Reduction of Thoroughbred racing fatalities at New York Racing Association racetracks using a multi-disciplinary mortality review process.

    PubMed

    Palmer, Scott E; McDonough, Sean P; Mohammed, Hussni O

    2017-07-01

    Between January 1, 2013 and December 31, 2015, findings of a New York State Gaming Commission-Cornell University postmortem examination program were utilized in a multi-disciplinary mortality review process to review 129 racing fatalities at Thoroughbred racetracks operated by the New York Racing Association (NYRA). Musculoskeletal fractures comprised 79% of the fatalities; cardiopulmonary conditions accounted for 12% of the fatalities. Other causes of death included gastrointestinal (3%), respiratory (5%), and central nervous system (2%) conditions. Fetlock failure represented 50% of the musculoskeletal fatalities. The general distribution of these findings was very similar to that reported by the California Animal Health and Food Safety Laboratory System during the same period. These findings, used in conjunction with a comprehensive mortality review process and regulatory reform, have contributed to a significant reduction of the incidence of Thoroughbred racing fatalities at NYRA racetracks during the period of this review.

  2. Reversing the conventional leather processing sequence for cleaner leather production.

    PubMed

    Saravanabhavan, Subramani; Thanikaivelan, Palanisamy; Rao, Jonnalagadda Raghava; Nair, Balachandran Unni; Ramasami, Thirumalachari

    2006-02-01

    Conventional leather processing generally involves a combination of single and multistep processes that employs as well as expels various biological, inorganic, and organic materials. It involves nearly 14-15 steps and discharges a huge amount of pollutants. This is primarily due to the fact that conventional leather processing employs a "do-undo" process logic. In this study, the conventional leather processing steps have been reversed to overcome the problems associated with the conventional method. The charges of the skin matrix and of the chemicals and pH profiles of the process have been judiciously used for reversing the process steps. This reversed process eventually avoids several acidification and basification/neutralization steps used in conventional leather processing. The developed process has been validated through various analyses such as chromium content, shrinkage temperature, softness measurements, scanning electron microscopy, and physical testing of the leathers. Further, the performance of the leathers is shown to be on par with conventionally processed leathers through bulk property evaluation. The process enjoys a significant reduction in COD and TS by 53 and 79%, respectively. Water consumption and discharge is reduced by 65 and 64%, respectively. Also, the process benefits from significant reduction in chemicals, time, power, and cost compared to the conventional process.

  3. A dynamic modelling framework towards the solution of reduction in smoking prevalence

    NASA Astrophysics Data System (ADS)

    Halim, Tisya Farida Abdul; Sapiri, Hasimah; Abidin, Norhaslinda Zainal

    2016-10-01

    This paper presents a hypothetical framework towards the solution for reduction in smoking prevalence in Malaysia. The framework is design to assist in decision making process related to reduction in smoking prevalence using SD and OCT. In general, this framework is developed using SD approach where OCT is embedded in the policy evaluation process. Smoking prevalence is one of the determinant which plays an important role in measuring a successful implementation of anti-smoking strategies. Therefore, it is critical to determine the optimal value of smoking prevalence in order to trim down the hazardous effects of smoking to society. Conversely, smoking problem becomes increasingly complex since many issues that ranged from behavioral to economical need to be considered simultaneously. Thus, a hypothetical framework of the control model embedded in the SD methodology is expected to obtain the minimum value of smoking prevalence which the output in turn will provide a guideline for tobacco researchers as well as decision makers for policy design and evaluation.

  4. Qualitative Exploration of the Potential Causes of Serious Reduction in Availability of Medicinal Plants in the Qinghai-Tibetan High Plateau

    PubMed Central

    Cuomu, Mingji

    2014-01-01

    In the last ten years, there has been a dramatic reduction in medicinal plants in Tibet. This situation has attracted the attention of many researchers from different professional backgrounds, yet very few documents have been published on the general theoretical context and the actual process of herb collection as it occurs at different levels in clinics in Tibet. This article begins with a systematic review of the general principles of medicinal plant collection methods as set out in the ancient traditional medical system. Because the demand for plants is generated by the need to make Tibetan medicines, it is necessary to consider the original context of Tibetan medicine to understand pharmacological needs and the principles behind collecting medicinal plants to develop a strategy that might guarantee sustainable development of the plant supply. After considering the wider context of this study, the article presents research mainly based on case studies with the intention of understanding different stakeholders’ experiences and social relationships in the contemporary herb collection process in order to discover behavioral patterns within the dynamic social roles involved in this process as these inform policy formation and to seek to promote appropriate methods in the future. PMID:25478035

  5. Cocatalysts in Semiconductor-based Photocatalytic CO2 Reduction: Achievements, Challenges, and Opportunities.

    PubMed

    Ran, Jingrun; Jaroniec, Mietek; Qiao, Shi-Zhang

    2018-02-01

    Ever-increasing fossil-fuel combustion along with massive CO 2 emissions has aroused a global energy crisis and climate change. Photocatalytic CO 2 reduction represents a promising strategy for clean, cost-effective, and environmentally friendly conversion of CO 2 into hydrocarbon fuels by utilizing solar energy. This strategy combines the reductive half-reaction of CO 2 conversion with an oxidative half reaction, e.g., H 2 O oxidation, to create a carbon-neutral cycle, presenting a viable solution to global energy and environmental problems. There are three pivotal processes in photocatalytic CO 2 conversion: (i) solar-light absorption, (ii) charge separation/migration, and (iii) catalytic CO 2 reduction and H 2 O oxidation. While significant progress is made in optimizing the first two processes, much less research is conducted toward enhancing the efficiency of the third step, which requires the presence of cocatalysts. In general, cocatalysts play four important roles: (i) boosting charge separation/transfer, (ii) improving the activity and selectivity of CO 2 reduction, (iii) enhancing the stability of photocatalysts, and (iv) suppressing side or back reactions. Herein, for the first time, all the developed CO 2 -reduction cocatalysts for semiconductor-based photocatalytic CO 2 conversion are summarized, and their functions and mechanisms are discussed. Finally, perspectives in this emerging area are provided. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Mapping grey matter reductions in schizophrenia: an anatomical likelihood estimation analysis of voxel-based morphometry studies.

    PubMed

    Fornito, A; Yücel, M; Patti, J; Wood, S J; Pantelis, C

    2009-03-01

    Voxel-based morphometry (VBM) is a popular tool for mapping neuroanatomical changes in schizophrenia patients. Several recent meta-analyses have identified the brain regions in which patients most consistently show grey matter reductions, although they have not examined whether such changes reflect differences in grey matter concentration (GMC) or grey matter volume (GMV). These measures assess different aspects of grey matter integrity, and may therefore reflect different pathological processes. In this study, we used the Anatomical Likelihood Estimation procedure to analyse significant differences reported in 37 VBM studies of schizophrenia patients, incorporating data from 1646 patients and 1690 controls, and compared the findings of studies using either GMC or GMV to index grey matter differences. Analysis of all studies combined indicated that grey matter reductions in a network of frontal, temporal, thalamic and striatal regions are among the most frequently reported in literature. GMC reductions were generally larger and more consistent than GMV reductions, and were more frequent in the insula, medial prefrontal, medial temporal and striatal regions. GMV reductions were more frequent in dorso-medial frontal cortex, and lateral and orbital frontal areas. These findings support the primacy of frontal, limbic, and subcortical dysfunction in the pathophysiology of schizophrenia, and suggest that the grey matter changes observed with MRI may not necessarily result from a unitary pathological process.

  7. Green reduction of graphene oxide by ascorbic acid

    NASA Astrophysics Data System (ADS)

    Khosroshahi, Zahra; Kharaziha, Mahshid; Karimzadeh, Fathallah; Allafchian, Alireza

    2018-01-01

    Graphene, a single layer of sp2-hybridized carbon atoms in a hexagonal (two-dimensional honey-comb) lattice, has attracted strong scientific and technological interest due to its novel and excellent optical, chemical, electrical, mechanical and thermal properties. The solution-processable chemical reduction of Graphene oxide (GO is considered as the most favorable method regarding mass production of graphene. Generally, the reduction of GO is carried out by chemical approaches using different reductants such as hydrazine and sodium borohydride. These components are corrosive, combustible and highly toxic which may be dangerous for personnel health and the environment. Hence, these reducing agents are not promising choice for reducing of graphene oxide (GO). As a consequence, it is necessary for further development and optimization of eco-friendly, natural reducing agent for clean and effective reduction of GO. Ascorbic acid, an eco-friendly and natural reducing agents, having a mild reductive ability and nontoxic property. So, the aim of this research was to green synthesis of GO with ascorbic acid. For this purpose, the required amount of NaOH and ascorbic acid were added to GO solution (0.5 mg/ml) and were heated at 95 °C for 1 hour. According to the X-ray powder diffraction (XRD), scanning electron microscopy (SEM), and electrochemical results, GO were reduced with ascorbic acid like hydrazine with better electrochemical properties and ascorbic acid is an ideal substitute for hydrazine in the reduction of graphene oxide process.

  8. Vapor Growth of Binary and Ternary Chalcogenides in Preparation for Microgravity Experiments

    NASA Technical Reports Server (NTRS)

    Su, C.; Whitaker, Ann F. (Technical Monitor)

    2001-01-01

    In the bulk crystal growth of some technologically important semiconducting chalcopyrites, such as ZnTe, CdS, ZnSe and ZnS, vapor growth techniques have significant advantages over melt growth techniques due to the high melting points of these materials. The realization of routine production of high-quality single crystals of these semiconductors requires a fundamental, systematic and in-depth study on the PVT growth process and crystal growth by vapor transport in low gravity offers a set of unique conditions for this study. Previously, two reasons have been put forward to account for this. The first is weight-related reductions in crystal strain and defects. These are thought to be caused by the weight of the crystals during processing at elevated temperatures and retained on cooling, particularly for materials with a low yield strength. The second, and more general, reason is related to the reduction in density-gradient driven convection. The PVT crystal growth process consists of essentially three processes: sublimation of the source material, transport of the vapor species and condensation of the vapor species to form the crystal. The latter two processes can be affected by the convection caused by gravitational accelerations on Earth. Reductions in such convection in low gravity is expected to yield a nearly diffusion-limited growth condition which results in more uniform growth rates (on the microscopic scale) and hence greater crystalline perfection and compositional homogeneity. The reduction of convective contamination by performing flight experiments in a reduced gravity environment will help to understand the relation between fluid phase processes (growth parameters) and defect and impurity incorporation in grown crystals.

  9. New Directions for the Photocatalytic Reduction of CO2: Supramolecular, scCO2 or Biphasic Ionic Liquid-scCO2 Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Grills, D.C.; Fujita, E.

    2010-09-02

    There is an urgent need for the discovery of carbon-neutral sources of energy to avoid the consequences of global warming caused by ever-increasing atmospheric CO{sub 2} levels. An attractive possibility is to use CO{sub 2} captured from industrial emissions as a feedstock for the production of useful fuels and precursors such as carbon monoxide and methanol. An active field of research to achieve this goal is the development of catalysts capable of harnessing solar energy for use in artificial photosynthetic processes for CO{sub 2} reduction. Transition-metal complexes are excellent candidates, and it has already been shown that they can bemore » used to reduce CO{sub 2} with high quantum efficiency. However, they generally suffer from poor visible light absorption, short catalyst lifetimes, and poor reaction rates. In this Perspective, the field of photocatalytic CO{sub 2} reduction is introduced, and recent developments that seek to improve the efficiency of such catalytic processes are highlighted, especially CO{sub 2} reduction with supramolecules and molecular systems in supercritical CO{sub 2} (scCO{sub 2}) or biphasic ionic liquid-scCO{sub 2} mixtures.« less

  10. ADART: an adaptive algebraic reconstruction algorithm for discrete tomography.

    PubMed

    Maestre-Deusto, F Javier; Scavello, Giovanni; Pizarro, Joaquín; Galindo, Pedro L

    2011-08-01

    In this paper we suggest an algorithm based on the Discrete Algebraic Reconstruction Technique (DART) which is capable of computing high quality reconstructions from substantially fewer projections than required for conventional continuous tomography. Adaptive DART (ADART) goes a step further than DART on the reduction of the number of unknowns of the associated linear system achieving a significant reduction in the pixel error rate of reconstructed objects. The proposed methodology automatically adapts the border definition criterion at each iteration, resulting in a reduction of the number of pixels belonging to the border, and consequently of the number of unknowns in the general algebraic reconstruction linear system to be solved, being this reduction specially important at the final stage of the iterative process. Experimental results show that reconstruction errors are considerably reduced using ADART when compared to original DART, both in clean and noisy environments.

  11. Emotional processing during experiential treatment of depression.

    PubMed

    Pos, Alberta E; Greenberg, Leslie S; Goldman, Rhonda N; Korman, Lorne M

    2003-12-01

    This study explored the importance of early and late emotional processing to change in depressive and general symptomology, self-esteem, and interpersonal problems for 34 clients who received 16-20 sessions of experiential treatment for depression. The independent contribution to outcome of the early working alliance was also explored. Early and late emotional processing predicted reductions in reported symptoms and gains in self-esteem. More important, emotional-processing skill significantly improved during treatment. Hierarchical regression models demonstrated that late emotional processing both mediated the relationship between clients' early emotional processing capacity and outcome and was the sole emotional-processing variable that independently predicted improvement. After controlling for emotional processing, the working alliance added an independent contribution to explaining improvement in reported symptomology only. (c) 2003 APA

  12. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wu, T.; Griffin, A. M.; Gorski, C. A.

    Dissimilatory microbial reduction of solid-phase Fe(III)-oxides and Fe(III)-bearing phyllosilicates (Fe(III)-phyllosilicates) is an important process in anoxic soils, sediments, and subsurface materials. Although various studies have documented the relative extent of microbial reduction of single-phase Fe(III)-oxides and Fe(III)-phyllosilicates, detailed information is not available on interaction between these two processes in situations where both phases are available for microbial reduction. The goal of this research was to use the model dissimilatory iron-reducing bacterium (DIRB) Geobacter sulfurreducens to study Fe(III)-oxide vs. Fe(III)-phyllosilicate reduction in a range of subsurface materials and Fe(III)-oxide stripped versions of the materials. Low temperature (12K) Mossbauer spectroscopy was usedmore » to infer changes in the relative abundances of Fe(III)-oxide, Fe(III)-phyllosilicate, and phyllosilicate-associated Fe(II) (Fe(II)-phyllosilicate). A Fe partitioning model was employed to analyze the fate of Fe(II) and assess the potential for abiotic Fe(II)-catalyzed reduction of Fe(III)-phyllosilicates. The results showed that in most cases Fe(III)- oxide utilization dominated (70-100 %) bulk Fe(III) reduction activity, and that electron transfer from oxide-derived Fe(II) played only a minor role (ca. 10-20 %) in Fe partitioning. In addition, the extent of Fe(III)-oxide reduction was positively correlated to surface area-normalized cation exchange capacity and the phyllosilicate-Fe(III)/total Fe(III) ratio, which suggests that the phyllosilicates in the natural sediments promoted Fe(III)-oxide reduction by binding of oxide-derived Fe(II), thereby enhancing Fe(III)-oxide reduction by reducing or delaying the inhibitory effect that Fe(II) accumulation on oxide and DIRB cell surfaces has on Fe(III)-oxide reduction. In general our results suggest that although Fe(III)-oxide reduction is likely to dominate bulk Fe(III) reduction in most subsurface sediments, Fe(II) binding by phyllosilicates is likely to play a key role in controlling the long-term kinetics of Fe(III)-oxide reduction.« less

  13. Parallelized modelling and solution scheme for hierarchically scaled simulations

    NASA Technical Reports Server (NTRS)

    Padovan, Joe

    1995-01-01

    This two-part paper presents the results of a benchmarked analytical-numerical investigation into the operational characteristics of a unified parallel processing strategy for implicit fluid mechanics formulations. This hierarchical poly tree (HPT) strategy is based on multilevel substructural decomposition. The Tree morphology is chosen to minimize memory, communications and computational effort. The methodology is general enough to apply to existing finite difference (FD), finite element (FEM), finite volume (FV) or spectral element (SE) based computer programs without an extensive rewrite of code. In addition to finding large reductions in memory, communications, and computational effort associated with a parallel computing environment, substantial reductions are generated in the sequential mode of application. Such improvements grow with increasing problem size. Along with a theoretical development of general 2-D and 3-D HPT, several techniques for expanding the problem size that the current generation of computers are capable of solving, are presented and discussed. Among these techniques are several interpolative reduction methods. It was found that by combining several of these techniques that a relatively small interpolative reduction resulted in substantial performance gains. Several other unique features/benefits are discussed in this paper. Along with Part 1's theoretical development, Part 2 presents a numerical approach to the HPT along with four prototype CFD applications. These demonstrate the potential of the HPT strategy.

  14. [Considerations concerning the theory of the demographic revolution. Its development in Cuba].

    PubMed

    Hernandez Castellon, R

    1983-01-01

    A review of the world's literature on the demographic transition is presented. The author, in his analysis of the non-Marxist literature, suggests that considerable efforts have been made to update demographic transition theory in order to take into account recent demographic trends in developing countries. On the other hand, the Marxist literature is divided into studies in which attempts are made to develop general demographic theories and those in which the value of such theories is questioned. The paper concludes with a description of the demographic transition process as it has been experienced in Cuba, and it is noted that a major feature of this process has been a general trend toward a reduction in demographic differentials.

  15. Chapter Two – Separations Versus Sustainability: There is No ...

    EPA Pesticide Factsheets

    Separation operations in chemical processes are generally “uphill” tasks—defying natural tendencies. Historically, such separations have been accomplished by applying generous portions of fossil energy and materials, leaving behind a large environmental footprint. In this chapter, progress in reducing this footprint will be discussed with examples in biofuel production, desalination, and carbon dioxide capture. Industrial separation processes have a significant energy and environmental footprint. Sizeable reductions in energy usage could be achieved by replacing energy-intensive processes like distillation with low-energy separation systems such as membranes, extraction, sorption, or synergistic hybrid systems of low- and high-energy systems.

  16. Digital processing of Mariner 9 television data.

    NASA Technical Reports Server (NTRS)

    Green, W. B.; Seidman, J. B.

    1973-01-01

    The digital image processing performed by the Image Processing Laboratory (IPL) at JPL in support of the Mariner 9 mission is summarized. The support is divided into the general categories of image decalibration (the removal of photometric and geometric distortions from returned imagery), computer cartographic projections in support of mapping activities, and adaptive experimenter support (flexible support to provide qualitative digital enhancements and quantitative data reduction of returned imagery). Among the tasks performed were the production of maximum discriminability versions of several hundred frames to support generation of a geodetic control net for Mars, and special enhancements supporting analysis of Phobos and Deimos images.

  17. The SCUBA Data Reduction Pipeline: ORAC-DR at the JCMT

    NASA Astrophysics Data System (ADS)

    Jenness, Tim; Economou, Frossie

    The ORAC data reduction pipeline, developed for UKIRT, has been designed to be a completely general approach to writing data reduction pipelines. This generality has enabled the JCMT to adapt the system for use with SCUBA with minimal development time using the existing SCUBA data reduction algorithms (Surf).

  18. Regularized Embedded Multiple Kernel Dimensionality Reduction for Mine Signal Processing.

    PubMed

    Li, Shuang; Liu, Bing; Zhang, Chen

    2016-01-01

    Traditional multiple kernel dimensionality reduction models are generally based on graph embedding and manifold assumption. But such assumption might be invalid for some high-dimensional or sparse data due to the curse of dimensionality, which has a negative influence on the performance of multiple kernel learning. In addition, some models might be ill-posed if the rank of matrices in their objective functions was not high enough. To address these issues, we extend the traditional graph embedding framework and propose a novel regularized embedded multiple kernel dimensionality reduction method. Different from the conventional convex relaxation technique, the proposed algorithm directly takes advantage of a binary search and an alternative optimization scheme to obtain optimal solutions efficiently. The experimental results demonstrate the effectiveness of the proposed method for supervised, unsupervised, and semisupervised scenarios.

  19. Soft-sensing model of temperature for aluminum reduction cell on improved twin support vector regression

    NASA Astrophysics Data System (ADS)

    Li, Tao

    2018-06-01

    The complexity of aluminum electrolysis process leads the temperature for aluminum reduction cells hard to measure directly. However, temperature is the control center of aluminum production. To solve this problem, combining some aluminum plant's practice data, this paper presents a Soft-sensing model of temperature for aluminum electrolysis process on Improved Twin Support Vector Regression (ITSVR). ITSVR eliminates the slow learning speed of Support Vector Regression (SVR) and the over-fit risk of Twin Support Vector Regression (TSVR) by introducing a regularization term into the objective function of TSVR, which ensures the structural risk minimization principle and lower computational complexity. Finally, the model with some other parameters as auxiliary variable, predicts the temperature by ITSVR. The simulation result shows Soft-sensing model based on ITSVR has short time-consuming and better generalization.

  20. Mechanical mid-story reduction treatments for forest fuel management

    Treesearch

    B. Rummer; K. Outcalt; D. Brockway

    2002-01-01

    There are many forest stands where exclusion of fire or lack of management has led to dense understorys and fuel accumulation. Generally, the least expensive treatment is to introduce a regime of prescribed fire as a surrogate for natural forest fire processes in these stands. However, in some cases prescribed fire is not an option. For example, heavy fuel loadings may...

  1. Modeling and optimization of reductive degradation of chloramphenicol in aqueous solution by zero-valent bimetallic nanoparticles.

    PubMed

    Singh, Kunwar P; Singh, Arun K; Gupta, Shikha; Rai, Premanjali

    2012-07-01

    The present study aims to investigate the individual and combined effects of temperature, pH, zero-valent bimetallic nanoparticles (ZVBMNPs) dose, and chloramphenicol (CP) concentration on the reductive degradation of CP using ZVBMNPs in aqueous medium. Iron-silver ZVBMNPs were synthesized. Batch experimental data were generated using a four-factor statistical experimental design. CP reduction by ZVBMNPs was optimized using the response surface modeling (RSM) and artificial neural network-genetic algorithm (ANN-GA) approaches. The RSM and ANN methodologies were also compared for their predictive and generalization abilities using the same training and validation data set. Reductive by-products of CP were identified using liquid chromatography-mass spectrometry technique. The optimized process variables (RSM and ANN-GA approaches) yielded CP reduction capacity of 57.37 and 57.10 mg g(-1), respectively, as compared to the experimental value of 54.0 mg g(-1) with un-optimized variables. The ANN-GA and RSM methodologies yielded comparable results and helped to achieve a higher reduction (>6%) of CP by the ZVBMNPs as compared to the experimental value. The root mean squared error, relative standard error of prediction and correlation coefficient between the measured and model-predicted values of response variable were 1.34, 3.79, and 0.964 for RSM and 0.03, 0.07, and 0.999 for ANN models for the training and 1.39, 3.47, and 0.996 for RSM and 1.25, 3.11, and 0.990 for ANN models for the validation set. Predictive and generalization abilities of both the RSM and ANN models were comparable. The synthesized ZVBMNPs may be used for an efficient reductive removal of CP from the water.

  2. An adaptive algorithm for the detection of microcalcifications in simulated low-dose mammography.

    PubMed

    Treiber, O; Wanninger, F; Führ, H; Panzer, W; Regulla, D; Winkler, G

    2003-02-21

    This paper uses the task of microcalcification detection as a benchmark problem to assess the potential for dose reduction in x-ray mammography. We present the results of a newly developed algorithm for detection of microcalcifications as a case study for a typical commercial film-screen system (Kodak Min-R 2000/2190). The first part of the paper deals with the simulation of dose reduction for film-screen mammography based on a physical model of the imaging process. Use of a more sensitive film-screen system is expected to result in additional smoothing of the image. We introduce two different models of that behaviour, called moderate and strong smoothing. We then present an adaptive, model-based microcalcification detection algorithm. Comparing detection results with ground-truth images obtained under the supervision of an expert radiologist allows us to establish the soundness of the detection algorithm. We measure the performance on the dose-reduced images in order to assess the loss of information due to dose reduction. It turns out that the smoothing behaviour has a strong influence on detection rates. For moderate smoothing. a dose reduction by 25% has no serious influence on the detection results. whereas a dose reduction by 50% already entails a marked deterioration of the performance. Strong smoothing generally leads to an unacceptable loss of image quality. The test results emphasize the impact of the more sensitive film-screen system and its characteristics on the problem of assessing the potential for dose reduction in film-screen mammography. The general approach presented in the paper can be adapted to fully digital mammography.

  3. An adaptive algorithm for the detection of microcalcifications in simulated low-dose mammography

    NASA Astrophysics Data System (ADS)

    Treiber, O.; Wanninger, F.; Führ, H.; Panzer, W.; Regulla, D.; Winkler, G.

    2003-02-01

    This paper uses the task of microcalcification detection as a benchmark problem to assess the potential for dose reduction in x-ray mammography. We present the results of a newly developed algorithm for detection of microcalcifications as a case study for a typical commercial film-screen system (Kodak Min-R 2000/2190). The first part of the paper deals with the simulation of dose reduction for film-screen mammography based on a physical model of the imaging process. Use of a more sensitive film-screen system is expected to result in additional smoothing of the image. We introduce two different models of that behaviour, called moderate and strong smoothing. We then present an adaptive, model-based microcalcification detection algorithm. Comparing detection results with ground-truth images obtained under the supervision of an expert radiologist allows us to establish the soundness of the detection algorithm. We measure the performance on the dose-reduced images in order to assess the loss of information due to dose reduction. It turns out that the smoothing behaviour has a strong influence on detection rates. For moderate smoothing, a dose reduction by 25% has no serious influence on the detection results, whereas a dose reduction by 50% already entails a marked deterioration of the performance. Strong smoothing generally leads to an unacceptable loss of image quality. The test results emphasize the impact of the more sensitive film-screen system and its characteristics on the problem of assessing the potential for dose reduction in film-screen mammography. The general approach presented in the paper can be adapted to fully digital mammography.

  4. Management of Sodium-reduced Meals at Worksite Cafeterias: Perceptions, Practices, Barriers, and Needs among Food Service Personnel.

    PubMed

    Lee, Jounghee; Park, Sohyun

    2016-04-01

    The sodium content of meals provided at worksite cafeterias is greater than the sodium content of restaurant meals and home meals. The objective of this study was to assess the relationships between sodium-reduction practices, barriers, and perceptions among food service personnel. We implemented a cross-sectional study by collecting data on perceptions, practices, barriers, and needs regarding sodium-reduced meals at 17 worksite cafeterias in South Korea. We implemented Chi-square tests and analysis of variance for statistical analysis. For post hoc testing, we used Bonferroni tests; when variances were unequal, we used Dunnett T3 tests. This study involved 104 individuals employed at the worksite cafeterias, comprised of 35 men and 69 women. Most of the participants had relatively high levels of perception regarding the importance of sodium reduction (very important, 51.0%; moderately important, 27.9%). Sodium reduction practices were higher, but perceived barriers appeared to be lower in participants with high-level perception of sodium-reduced meal provision. The results of the needs assessment revealed that the participants wanted to have more active education programs targeting the general population. The biggest barriers to providing sodium-reduced meals were use of processed foods and limited methods of sodium-reduced cooking in worksite cafeterias. To make the provision of sodium-reduced meals at worksite cafeterias more successful and sustainable, we suggest implementing more active education programs targeting the general population, developing sodium-reduced cooking methods, and developing sodium-reduced processed foods.

  5. FinalReport-DOE BES DMSE-UNR-QLi

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Qizhen

    The primary goal of this project is to explore the fundamental deformation and failure mechanisms for magnesium with a hexagonal close packed (HCP) crystal structure. It is critical to perform this project for a number of reasons. First, magnesium is the lightest structural metal and its application in various structural components can save the final component weight. Second, the weight reduction from the usage of magnesium-based structural components in transportation vehicles such as automobiles and aircrafts can improve fuel efficiency and reduce the greenhouse gas emissions. Third, structural components often experience dynamic loading such as cyclic loading conditions. Fourth, magnesiummore » with a HCP crystal structure generally has its special deformation responses under loading conditions. This project investigated magnesium based materials (magnesium single crystal, pure polycrystalline magnesium, and some magnesium alloys) under various loading conditions, and also explored some processing routes to manipulate the microstructure and mechanical properties of magnesium. The research results were published in a number of articles and also disseminated through presentations in various conferences such as TMS annual meetings, MRS meetings, the international Plasticity conferences, the Pacific Rim International Congress on Advanced Materials and Processing, and AeroMat. In addition to the contribution to the research/academic community, this project is also beneficial to the general public. With the actual usage of magnesium in the passenger cars, the weight reduction and fuel consumption reduction will save the fuel bill of individual owners.« less

  6. Analysis of E-marketplace Attributes: Assessing The NATO Logistics Stock Exchange

    DTIC Science & Technology

    2008-01-01

    order processing time Reduction of stock levels Reduction of payment processing time Reduction of excessive stocks Reduction of maverick buying...satisfaction 4,02 0,151 3. Reduction of order processing time 4,27 0,317 15. Reduction of stock levels 3,87 0,484 4. Reduction of payment processing time...information exchange with partners in the supply chain Efficiency Basic Reduction of order processing time Efficiency Important Reduction of

  7. Advanced multilateration theory, software development, and data processing: The MICRODOT system

    NASA Technical Reports Server (NTRS)

    Escobal, P. R.; Gallagher, J. F.; Vonroos, O. H.

    1976-01-01

    The process of geometric parameter estimation to accuracies of one centimeter, i.e., multilateration, is defined and applications are listed. A brief functional explanation of the theory is presented. Next, various multilateration systems are described in order of increasing system complexity. Expected systems accuracy is discussed from a general point of view and a summary of the errors is listed. An outline of the design of a software processing system for multilateration, called MICRODOT, is presented next. The links of this software, which can be used for multilateration data simulations or operational data reduction, are examined on an individual basis. Functional flow diagrams are presented to aid in understanding the software capability. MICRODOT capability is described with respect to vehicle configurations, interstation coordinate reduction, geophysical parameter estimation, and orbit determination. Numerical results obtained from MICRODOT via data simulations are displayed both for hypothetical and real world vehicle/station configurations such as used in the GEOS-3 Project. These simulations show the inherent power of the multilateration procedure.

  8. The role of regional heterogeneity in age-related differences in functional hemispheric asymmetry: an fMRI study.

    PubMed

    Heng, Jiamin Gladys; Wu, Chiao-Yi; Archer, Josephine Astrid; Miyakoshi, Makoto; Nakai, Toshiharu; Chen, Shen-Hsing Annabel

    2017-10-09

    Neuroimaging literature has documented age-related hemispheric asymmetry reduction in frontal regions during task performances. As most studies employed working memory paradigms, it is therefore less clear if this pattern of neural reorganization is constrained by working memory processes or it would also emerge in other cognitive domains which are predominantly lateralized. Using blocked functional magnetic resonance imaging (fMRI), the present study used a homophone judgment task and a line judgment task to investigate age-related differences in functional hemispheric asymmetry in language and visuospatial processing respectively. Young and older adults achieved similar task accuracy although older adults required a significantly longer time. Age-related functional hemispheric asymmetry reduction was found only in dorsal inferior frontal gyrus and was associated with better performance when the homophone condition was contrasted against fixation, and not line condition. Our data thus highlights the importance of considering regional heterogeneity of aging effects together with general age-related cognitive processes.

  9. 44 CFR 361.7 - General eligible expenditures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS NATIONAL EARTHQUAKE HAZARDS REDUCTION ASSISTANCE TO STATE AND LOCAL GOVERNMENTS Earthquake Hazards Reduction Assistance Program § 361.7 General eligible expenditures... specifically for carrying out earthquake hazards reduction activities are eligible when engaged in the...

  10. 44 CFR 361.7 - General eligible expenditures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS NATIONAL EARTHQUAKE HAZARDS REDUCTION ASSISTANCE TO STATE AND LOCAL GOVERNMENTS Earthquake Hazards Reduction Assistance Program § 361.7 General eligible expenditures... specifically for carrying out earthquake hazards reduction activities are eligible when engaged in the...

  11. 44 CFR 361.7 - General eligible expenditures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS NATIONAL EARTHQUAKE HAZARDS REDUCTION ASSISTANCE TO STATE AND LOCAL GOVERNMENTS Earthquake Hazards Reduction Assistance Program § 361.7 General eligible expenditures... specifically for carrying out earthquake hazards reduction activities are eligible when engaged in the...

  12. 44 CFR 361.7 - General eligible expenditures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS NATIONAL EARTHQUAKE HAZARDS REDUCTION ASSISTANCE TO STATE AND LOCAL GOVERNMENTS Earthquake Hazards Reduction Assistance Program § 361.7 General eligible expenditures... specifically for carrying out earthquake hazards reduction activities are eligible when engaged in the...

  13. 44 CFR 361.7 - General eligible expenditures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS NATIONAL EARTHQUAKE HAZARDS REDUCTION ASSISTANCE TO STATE AND LOCAL GOVERNMENTS Earthquake Hazards Reduction Assistance Program § 361.7 General eligible expenditures... specifically for carrying out earthquake hazards reduction activities are eligible when engaged in the...

  14. Overview of reductants utilized in nuclear fuel reprocessing/recycling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Patricia Paviet-Hartmann; Catherine Riddle; Keri Campbell

    2013-10-01

    Most of the aqueous processes developed, or under consideration worldwide for the recycling of used nuclear fuel (UNF) utilize the oxido-reduction properties of actinides to separate them from other radionuclides. Generally, after acid dissolution of the UNF, (essentially in nitric acid solution), actinides are separated from the raffinate by liquid-liquid extraction using specific solvents, associated along the process, with a particular reductant that will allow the separation to occur. For example, the industrial PUREX process utilizes hydroxylamine as a plutonium reductant. Hydroxylamine has numerous advantages: not only does it have the proper attributes to reduce Pu(IV) to Pu(III), but itmore » is also a non-metallic chemical that is readily decomposed to innocuous products by heating. However, it has been observed that the presence of high nitric acid concentrations or impurities (such as metal ions) in hydroxylamine solutions increase the likelihood of the initiation of an autocatalytic reaction. Recently there has been some interest in the application of simple hydrophilic hydroxamic ligands such as acetohydroxamic acid (AHA) for the stripping of tetravalent actinides in the UREX process flowsheet. This approach is based on the high coordinating ability of hydroxamic acids with tetravalent actinides (Np and Pu) compared with hexavalent uranium. Thus, the use of AHA offers a route for controlling neptunium and plutonium in the UREX process by complexant based stripping of Np(IV) and Pu(IV) from the TBP solvent phase, while U(VI) ions are not affected by AHA and remain solvated in the TBP phase. In the European GANEX process, AHA is also used to form hydrophilic complexes with actinides and strip them from the organic phase into nitric acid. However, AHA does not decompose completely when treated with nitric acid and hampers nitric acid recycling. In lieu of using AHA in the UREX + process, formohydroxamic acid (FHA), although not commercially available, hold promises as a replacement for AHA. FHA undergoes hydrolysis to formic acid which is volatile, thus allowing the recycling of nitric acid. Unfortunately, FHA powder was not stable in the experiments we ran in our laboratory. In addition, AHA and FHA also decompose to hydroxylamine which may undergo an autocatalytic reaction. Other reductants are available and could be extremely useful for actinides separation. The review presents the current plutonium reductants used in used nuclear fuel reprocessing and will introduce innovative and novel reductants that could become reducers for future research on UNF separation.« less

  15. Performance evaluation of extractor cutting blade configuration in Inulin extraction process from Dahlia sp. L tuber

    NASA Astrophysics Data System (ADS)

    Sundari, E.; Praputri, E.; Marthiana, W.; Jaya, M.

    2018-03-01

    Inulin, a polysaccharide plant-based nutrient, can be isolated from dahlia flower tubers by liquid-solid extraction processes and is generally carried out in an extractor tank equipped with an agitator. To accelerate the diffusion rate of solute from the solid phase (bulk phase) to the external surface (boundary layer) in order to increase yield of inulin, the size reduction of material is required. The purpose of this research was to design the cutting blade needed for dahlia tuber size reduction and investigate the effect of blade types, agitator speed (350, 700, 1050, and 1400 rpm), and configuration of cutting blade to material fineness at 90 minutes of contacting time. The results showed that higher cutting blade speed results in higher cut material fineness rate. The best conditions was achieved by the configuration of two four-blade turbine combined with one three-blade turbine with fineness rate more than 90% in 30 minutes of contacting time at every variation of agitator speed. The cutting blade designed in this study can be used for size reduction purpose of tubers other than dahlia tubers.

  16. The development of a laterally confined laboratory fan delta under sediment supply reduction

    NASA Astrophysics Data System (ADS)

    Zhang, Xiaofeng; Wang, Siqiang; Wu, Xi; Xu, Shun; Li, Zhangyong

    2016-03-01

    In previous fan delta experiments, the effect of lateral confinement was generally ignored as these fans were usually unconfined with semiconical geometries. However, in gorge areas, fan development is usually laterally confined by valley walls. This study investigates autogenic processes of fan deltas in a laterally confined experimental tank. The experiment is divided into three phases. The sediment supply is held constant within each phase, so the autogenic processes of the fan are separated from the allogenic forcings. Results indicate that laterally confined fan deltas have higher progradation and aggradation potential, more regular channel braiding, and more even transverse sedimentation than unconfined fans. Besides, responses of fan deltas to sediment supply reduction are investigated in this research. At the initiation of the second and third phases, sediment feed rates are instantaneously reduced so that the allogenic forcings are predominant. Observations show that under sediment supply reduction, channelization on fan deltas are more pronounced and durations of the fluvial cycles are longer. The adjustment of fan morphology becomes slower as the self-regulation capacity of the fan decreases with reduced sediment supply.

  17. Effects of technological processes on enniatin levels in pasta.

    PubMed

    Serrano, Ana B; Font, Guillermina; Mañes, Jordi; Ferrer, Emilia

    2016-03-30

    Potential human health risks posed by enniatins (ENs) require their control primarily from cereal products, creating a demand for harvesting, food processing and storage techniques capable to prevent, reduce and/or eliminate the contamination. In this study, different methodologies to pasta processing simulating traditional and industrial processes were developed in order to know the fate of the mycotoxin ENs. The levels of ENs were studied at different steps of pasta processing. The effect of the temperature during processing was evaluated in two types of pasta (white and whole-grain pasta). Mycotoxin analysis was performed by LC-MS/MS. High reductions (up to 50% and 80%) were achieved during drying pasta at 45-55°C and 70-90°C, respectively. The treatments at low temperature (25°C) did not change EN levels. The effect of pasta composition did not cause a significant effect on the stability of ENs. The effect of the temperature allowed a marked mycotoxin reduction during pasta processing. Generally, ENA1 and ENB showed higher thermal stability than did ENA and ENB1 . The findings from the present study suggested that pasta processing at medium-high temperatures is a potential tool to remove an important fraction of ENs from the initial durum wheat semolina. © 2015 Society of Chemical Industry.

  18. Parallelization strategies for continuum-generalized method of moments on the multi-thread systems

    NASA Astrophysics Data System (ADS)

    Bustamam, A.; Handhika, T.; Ernastuti, Kerami, D.

    2017-07-01

    Continuum-Generalized Method of Moments (C-GMM) covers the Generalized Method of Moments (GMM) shortfall which is not as efficient as Maximum Likelihood estimator by using the continuum set of moment conditions in a GMM framework. However, this computation would take a very long time since optimizing regularization parameter. Unfortunately, these calculations are processed sequentially whereas in fact all modern computers are now supported by hierarchical memory systems and hyperthreading technology, which allowing for parallel computing. This paper aims to speed up the calculation process of C-GMM by designing a parallel algorithm for C-GMM on the multi-thread systems. First, parallel regions are detected for the original C-GMM algorithm. There are two parallel regions in the original C-GMM algorithm, that are contributed significantly to the reduction of computational time: the outer-loop and the inner-loop. Furthermore, this parallel algorithm will be implemented with standard shared-memory application programming interface, i.e. Open Multi-Processing (OpenMP). The experiment shows that the outer-loop parallelization is the best strategy for any number of observations.

  19. [Which Factors Affect Weight Maintenance? A Qualitative Study with Adolescents and their Parents who have Completed a Ten-months Intervention].

    PubMed

    Hemetek, U; Ernert, A; Wiegand, S; Bau, A-M

    2015-11-01

    The alarming increase in the prevalence of childhood obesity is recognised as a major public health concern. Currently, structured multi-modal therapy programmes present the gold standard of therapy strategies for obese children and adolescents. However, effects of these treatments are still a matter of discussion. Failure to isolate and understand the external and internal factors contributing to successful, long-term weight reduction may well be contributing to the ineffectiveness of current treatment interventions. A qualitative approach was chosen in order to identify subjectively perceived resources and barriers to weight maintenance after previous weight reduction. The research question focused on how these resources and barriers affect success of participants. Additionally the question arose as to how and to what extent parents should and could be involved in the therapy process. The results can deliver important starting points for the development of therapy programmes and future research. 7 participants of a weight reduction and maintenance programme and 7 of their parents were interviewed on their personal experiences during and after the treatment. The interviews were analysed based on the qualitative content analysis. Continuous motivation, especially after the initial weight reduction phase, was identified as the strongest predictor of successful weight maintenance. Successful weight maintainers generally showed characteristics of higher self-efficacy, internal motivation concerning physical activity and flexible self-control concerning food intake. Unsuccessful weight gainers stated a lack of motivation concerning physical activity and lost control over their eating habits. Concerning the role of parents in the therapy process, the results show that higher parental involvement does not predict greater success. The general relationship between parents and their children seems to be more significant, especially concerning the issues of responsibility. It is disputable to what extent the post treatment intervention contributed to the development of intrinsic motivation. More attention should be paid to the age (children or adolescents) of participants of therapy programmes, especially concerning the involvement of parents. It is assumed that general aspects of education should be discussed with parents. © Georg Thieme Verlag KG Stuttgart · New York.

  20. Performing a local reduction operation on a parallel computer

    DOEpatents

    Blocksome, Michael A; Faraj, Daniel A

    2013-06-04

    A parallel computer including compute nodes, each including two reduction processing cores, a network write processing core, and a network read processing core, each processing core assigned an input buffer. Copying, in interleaved chunks by the reduction processing cores, contents of the reduction processing cores' input buffers to an interleaved buffer in shared memory; copying, by one of the reduction processing cores, contents of the network write processing core's input buffer to shared memory; copying, by another of the reduction processing cores, contents of the network read processing core's input buffer to shared memory; and locally reducing in parallel by the reduction processing cores: the contents of the reduction processing core's input buffer; every other interleaved chunk of the interleaved buffer; the copied contents of the network write processing core's input buffer; and the copied contents of the network read processing core's input buffer.

  1. Performing a local reduction operation on a parallel computer

    DOEpatents

    Blocksome, Michael A.; Faraj, Daniel A.

    2012-12-11

    A parallel computer including compute nodes, each including two reduction processing cores, a network write processing core, and a network read processing core, each processing core assigned an input buffer. Copying, in interleaved chunks by the reduction processing cores, contents of the reduction processing cores' input buffers to an interleaved buffer in shared memory; copying, by one of the reduction processing cores, contents of the network write processing core's input buffer to shared memory; copying, by another of the reduction processing cores, contents of the network read processing core's input buffer to shared memory; and locally reducing in parallel by the reduction processing cores: the contents of the reduction processing core's input buffer; every other interleaved chunk of the interleaved buffer; the copied contents of the network write processing core's input buffer; and the copied contents of the network read processing core's input buffer.

  2. Decision-Making Processes during State Appropriation Cuts in Michigan Public Universities: How Administrators Respond to These Cuts a Case Study of State "A" University

    ERIC Educational Resources Information Center

    Almeshagbeh, Wasfi K.

    2012-01-01

    In principle and practice, Michigan's public universities are committed to the sustained improvement of educational and economic opportunities in the state. However, their place in the state's general fund budget makes them especially vulnerable to reductions, when resources are low. The remarkable impact that higher education has on every person…

  3. Design concepts for a composite door frame system for general automotive applications

    NASA Technical Reports Server (NTRS)

    Tauber, J. A.

    1976-01-01

    Conceptual design, manufacturing process, and costs are explored to determine the feasibility of replacing present steel parts in automotive door structures with various composite materials. The problems of conforming to present anti-intrusion specifications with advanced materials are examined and discussed. Modest weight reductions, at competitive costs, were identified for the utilization of specific composite materials in automotive door structures.

  4. Kinetics of the reduction of bushveld complex chromite ore at 1416 °C

    NASA Astrophysics Data System (ADS)

    Soykan, O.; Eric, R. H.; King, R. P.

    1991-12-01

    The kinetics of the reduction of chromite ore from the LG-6 layer of the Bushveld Complex of the Transvaal in South Africa were studied at 1416 °C by the thermogravimetric analysis (TGA) technique. Spectroscopic graphite powder was employed as the reductant. The aim of this article is to present a kinetic model that satisfactorily describes the solid-state carbothermic reduction of chromite. A generalized rate model based on an ionic diffusion mechanism was developed. The model included the contribution of the interfacial area between partially reduced and unreduced zones in chromite particles and diffusion. The kinetic model described the process for degrees of reduction from 10 to 75 pet satisfactorily. It was observed that at a given particle size, the rate of reduction was controlled mainly by interfacial area up to about 40 pet reduction, after which the rate was dominated by diffusion. On the other hand, for a given degree of reduction, the contribution of the interfacial area to the rate increased, while that of diffusion decreased, with a decrease in the particle size. The value of the diffusion coefficient for the Fe2+ species at 1416 °C was calculated to be 2.63 x 10-2 cm2/s.

  5. The 3 faces of clinical reasoning: Epistemological explorations of disparate error reduction strategies.

    PubMed

    Monteiro, Sandra; Norman, Geoff; Sherbino, Jonathan

    2018-06-01

    There is general consensus that clinical reasoning involves 2 stages: a rapid stage where 1 or more diagnostic hypotheses are advanced and a slower stage where these hypotheses are tested or confirmed. The rapid hypothesis generation stage is considered inaccessible for analysis or observation. Consequently, recent research on clinical reasoning has focused specifically on improving the accuracy of the slower, hypothesis confirmation stage. Three perspectives have developed in this line of research, and each proposes different error reduction strategies for clinical reasoning. This paper considers these 3 perspectives and examines the underlying assumptions. Additionally, this paper reviews the evidence, or lack of, behind each class of error reduction strategies. The first perspective takes an epidemiological stance, appealing to the benefits of incorporating population data and evidence-based medicine in every day clinical reasoning. The second builds on the heuristic and bias research programme, appealing to a special class of dual process reasoning models that theorizes a rapid error prone cognitive process for problem solving with a slower more logical cognitive process capable of correcting those errors. Finally, the third perspective borrows from an exemplar model of categorization that explicitly relates clinical knowledge and experience to diagnostic accuracy. © 2018 John Wiley & Sons, Ltd.

  6. Online dimensionality reduction using competitive learning and Radial Basis Function network.

    PubMed

    Tomenko, Vladimir

    2011-06-01

    The general purpose dimensionality reduction method should preserve data interrelations at all scales. Additional desired features include online projection of new data, processing nonlinearly embedded manifolds and large amounts of data. The proposed method, called RBF-NDR, combines these features. RBF-NDR is comprised of two modules. The first module learns manifolds by utilizing modified topology representing networks and geodesic distance in data space and approximates sampled or streaming data with a finite set of reference patterns, thus achieving scalability. Using input from the first module, the dimensionality reduction module constructs mappings between observation and target spaces. Introduction of specific loss function and synthesis of the training algorithm for Radial Basis Function network results in global preservation of data structures and online processing of new patterns. The RBF-NDR was applied for feature extraction and visualization and compared with Principal Component Analysis (PCA), neural network for Sammon's projection (SAMANN) and Isomap. With respect to feature extraction, the method outperformed PCA and yielded increased performance of the model describing wastewater treatment process. As for visualization, RBF-NDR produced superior results compared to PCA and SAMANN and matched Isomap. For the Topic Detection and Tracking corpus, the method successfully separated semantically different topics. Copyright © 2011 Elsevier Ltd. All rights reserved.

  7. Bosch CO2 Reduction System Development

    NASA Technical Reports Server (NTRS)

    Holmes, R. F.; King, C. D.; Keller, E. E.

    1975-01-01

    Refinements in the design of a Bosch CO2 reduction unit for spacecraft O2 production are described. Sealing of the vacuum insulation jacket was simplified so that high vacuum and high insulation performance are easily maintained. The device includes a relatively simple concentric shell recuperative heat exchanger which operates at approximately 95% temperature effectiveness and helps lower power consumption. The influence of reactor temperature, pressure, and recycle gas composition on power consumption was investigated. In general, precise control is not required since power consumption is not very sensitive to moderate variations of these parameters near their optimum values. There are two process rate control modes which match flow rate to process demand. Catalyst conditioning, support, and packing pattern developments assure consistent starts, reduced energy consumption, and extended cartridge life. Operation levels for four or five men were maintained with overall power input values of 50 to 60 watts per man.

  8. Meditation-induced neuroplastic changes in amygdala activity during negative affective processing.

    PubMed

    Leung, Mei-Kei; Lau, Way K W; Chan, Chetwyn C H; Wong, Samuel S Y; Fung, Annis L C; Lee, Tatia M C

    2018-06-01

    Recent evidence suggests that the effects of meditation practice on affective processing and resilience have the potential to induce neuroplastic changes within the amygdala. Notably, literature speculates that meditation training may reduce amygdala activity during negative affective processing. Nonetheless, studies have thus far not verified this speculation. In this longitudinal study, participants (N = 21, 9 men) were trained in awareness-based compassion meditation (ABCM) or matched relaxation training. The effects of meditation training on amygdala activity were examined during passive viewing of affective and neutral stimuli in a non-meditative state. We found that the ABCM group exhibited significantly reduced anxiety and right amygdala activity during negative emotion processing than the relaxation group. Furthermore, ABCM participants who performed more compassion practice had stronger right amygdala activity reduction during negative emotion processing. The lower right amygdala activity after ABCM training may be associated with a general reduction in reactivity and distress. As all participants performed the emotion processing task in a non-meditative state, it appears likely that the changes in right amygdala activity are carried over from the meditation practice into the non-meditative state. These findings suggest that the distress-reducing effects of meditation practice on affective processing may transfer to ordinary states, which have important implications on stress management.

  9. Rugometric and microtopographic inspection of teeth enamel

    NASA Astrophysics Data System (ADS)

    Costa, Manuel F.; Pereira, Pedro B.

    2013-06-01

    The roughness of teeth' enamel is an important parameter in orthodontics. One example is the application in the process of decreasing tooth-size by reducing the interproximal enamel surfaces (stripping) of teeth. In order to achieve smooth surfaces clinicians have been testing various methods and progressively improved this therapeutic technique. The evaluation the surface roughness following teeth interproximal reduction is fundamental in the process. In general tooth' surface is not flat presenting a variety of complex geometries. In this communication we will report on the metrological procedure employed on the rugometric and microtopographic inspection by optical active triangulation of raw and processed (interproximal stripping) tooth surfaces.

  10. A new method for calculating differential distributions directly in Mellin space

    NASA Astrophysics Data System (ADS)

    Mitov, Alexander

    2006-12-01

    We present a new method for the calculation of differential distributions directly in Mellin space without recourse to the usual momentum-fraction (or z-) space. The method is completely general and can be applied to any process. It is based on solving the integration-by-parts identities when one of the powers of the propagators is an abstract number. The method retains the full dependence on the Mellin variable and can be implemented in any program for solving the IBP identities based on algebraic elimination, like Laporta. General features of the method are: (1) faster reduction, (2) smaller number of master integrals compared to the usual z-space approach and (3) the master integrals satisfy difference instead of differential equations. This approach generalizes previous results related to fully inclusive observables like the recently calculated three-loop space-like anomalous dimensions and coefficient functions in inclusive DIS to more general processes requiring separate treatment of the various physical cuts. Many possible applications of this method exist, the most notable being the direct evaluation of the three-loop time-like splitting functions in QCD.

  11. Loss Reduction on Adoption of High Voltage LT Less Distribution

    NASA Astrophysics Data System (ADS)

    Tiwari, Deepika; Adhikari, Nikhileshwar Prasad; Gupta, Amit; Bajpai, Santosh Kumar

    2016-06-01

    In India there is a need to improve the quality of the electricity distribution process which has increased varying from year to year. In distribution networks, the limiting factor to load carrying capacity is generally the voltage reduction. High voltage distribution system (HVDS) is one of the steps to reduce line losses in electrical distribution network. It helps to reduce the length of low tension (LT) lines and makes the power available close to the users. The high voltage power distribution system reduces the probability of power theft by hooking HVDS suggests an increase in installation of small capacity single-phase transformers in the network which again save considerable energy. This paper is compared to existing conventional low tension distribution network with HVDS. The paper gives a clear picture of reduction in distribution losses with adoption of HVDS system. Losses Reduction of 11 kV Feeder in Nuniya (India) with adoption of HVDS have been worked out/ quantified and benefits thereby in generating capacity have discussed.

  12. Influence of the size reduction of organic waste on their anaerobic digestion.

    PubMed

    Palmowski, L M; Müller, J A

    2000-01-01

    The rate-limiting step in anaerobic digestion of organic solid waste is generally their hydrolysis. A size reduction of the particles and the resulting enlargement of the available specific surface can support the biological process in two ways. Firstly, in case of substrates with a high content of fibres and a low xegradability, their comminution yields to an improved digester gas production. This leads to a decreased amount of residues to be disposed of and to an increased quantity of useful digester gas. The second effect of the particle size reduction observed with all the substrates but particularly with those of low degradability is a reduction of the technical digestion time. Furthermore, the particle size of organic waste has an influence on the dewaterability after codigestion with sewage sludge. The presence of organic waste residues improves the dewaterability measured as specific resistance to filtration but this positive effect is attenuated if the particle size of the solids is reduced.

  13. Amorphous nickel boride membrane on a platinum-nickel alloy surface for enhanced oxygen reduction reaction.

    PubMed

    He, Daping; Zhang, Libo; He, Dongsheng; Zhou, Gang; Lin, Yue; Deng, Zhaoxiang; Hong, Xun; Wu, Yuen; Chen, Chen; Li, Yadong

    2016-08-09

    The low activity of the oxygen reduction reaction in polymer electrolyte membrane fuel cells is a major barrier for electrocatalysis, and hence needs to be optimized. Tuning the surface electronic structure of platinum-based bimetallic alloys, a promising oxygen reduction reaction catalyst, plays a key role in controlling its interaction with reactants, and thus affects the efficiency. Here we report that a dealloying process can be utilized to experimentally fabricate the interface between dealloyed platinum-nickel alloy and amorphous nickel boride membrane. The coating membrane works as an electron acceptor to tune the surface electronic structure of the platinum-nickel catalyst, and this composite catalyst composed of crystalline platinum-nickel covered by amorphous nickel boride achieves a 27-times enhancement in mass activity relative to commercial platinum/carbon at 0.9 V for the oxygen reduction reaction performance. Moreover, this interactional effect between a crystalline surface and amorphous membrane can be readily generalized to facilitate the 3-times higher catalytic activity of commercial platinum/carbon.

  14. The impact of new forms of large-scale general practice provider collaborations on England's NHS: a systematic review.

    PubMed

    Pettigrew, Luisa M; Kumpunen, Stephanie; Mays, Nicholas; Rosen, Rebecca; Posaner, Rachel

    2018-03-01

    Over the past decade, collaboration between general practices in England to form new provider networks and large-scale organisations has been driven largely by grassroots action among GPs. However, it is now being increasingly advocated for by national policymakers. Expectations of what scaling up general practice in England will achieve are significant. To review the evidence of the impact of new forms of large-scale general practice provider collaborations in England. Systematic review. Embase, MEDLINE, Health Management Information Consortium, and Social Sciences Citation Index were searched for studies reporting the impact on clinical processes and outcomes, patient experience, workforce satisfaction, or costs of new forms of provider collaborations between general practices in England. A total of 1782 publications were screened. Five studies met the inclusion criteria and four examined the same general practice networks, limiting generalisability. Substantial financial investment was required to establish the networks and the associated interventions that were targeted at four clinical areas. Quality improvements were achieved through standardised processes, incentives at network level, information technology-enabled performance dashboards, and local network management. The fifth study of a large-scale multisite general practice organisation showed that it may be better placed to implement safety and quality processes than conventional practices. However, unintended consequences may arise, such as perceptions of disenfranchisement among staff and reductions in continuity of care. Good-quality evidence of the impacts of scaling up general practice provider organisations in England is scarce. As more general practice collaborations emerge, evaluation of their impacts will be important to understand which work, in which settings, how, and why. © British Journal of General Practice 2018.

  15. The Effect of a Workplace-Based Early Intervention Program on Work-Related Musculoskeletal Compensation Outcomes at a Poultry Meat Processing Plant.

    PubMed

    Donovan, Michael; Khan, Asaduzzaman; Johnston, Venerina

    2017-03-01

    Introduction The aim of this study is to determine whether a workplace-based early intervention injury prevention program reduces work-related musculoskeletal compensation outcomes in poultry meat processing workers. Methods A poultry meatworks in Queensland, Australia implemented an onsite early intervention which included immediate reporting and triage, reassurance, multidisciplinary participatory consultation, workplace modifica tion and onsite physiotherapy. Secondary pre-post analyses of the meatworks' compensation data over 4 years were performed, with the intervention commencing 2 years into the study period. Outcome measures included rate of claims, costs per claim and work days absent at an individual claim level. Where possible, similar analyses were performed on data for Queensland's poultry meat processing industry (excluding the meatworks used in this study). Results At the intervention meatworks, in the post intervention period an 18 % reduction in claims per 1 million working hours (p = 0.017) was observed. Generalized linear modelling revealed a significant reduction in average costs per claim of $831 (OR 0.74; 95 % CI 0.59-0.93; p = 0.009). Median days absent was reduced by 37 % (p = 0.024). For the poultry meat processing industry over the same period, generalized linear modelling revealed no significant change in average costs per claim (OR 1.02; 95 % CI 0.76-1.36; p = 0.91). Median days absent was unchanged (p = 0.93). Conclusion The introduction of an onsite, workplace-based early intervention injury prevention program demonstrated positive effects on compensation outcomes for work-related musculoskeletal disorders in poultry meat processing workers. Prospective studies are needed to confirm the findings of the present study.

  16. Sulfur transformations in pilot-scale constructed wetland treating high sulfate-containing contaminated groundwater: a stable isotope assessment.

    PubMed

    Wu, Shubiao; Jeschke, Christina; Dong, Renjie; Paschke, Heidrun; Kuschk, Peter; Knöller, Kay

    2011-12-15

    Current understanding of the dynamics of sulfur compounds inside constructed wetlands is still insufficient to allow a full description of processes involved in sulfur cycling. Experiments in a pilot-scale horizontal subsurface flow constructed wetland treating high sulfate-containing contaminated groundwater were carried out. Application of stable isotope approach combined with hydro-chemical investigations was performed to evaluate the sulfur transformations. In general, under inflow concentration of about 283 mg/L sulfate sulfur, sulfate removal was found to be about 21% with a specific removal rate of 1.75 g/m(2)·d. The presence of sulfide and elemental sulfur in pore water about 17.3 mg/L and 8.5 mg/L, respectively, indicated simultaneously bacterial sulfate reduction and re-oxidation. 70% of the removed sulfate was calculated to be immobilized inside the wetland bed. The significant enrichment of (34)S and (18)O in dissolved sulfate (δ(34)S up to 16‰, compared to average of 5.9‰ in the inflow, and δ(18)O up to 13‰, compared to average of 6.9‰ in the inflow) was observed clearly correlated to the decrease of sulfate loads along the flow path through experimental wetland bed. This enrichment also demonstrated the occurrence of bacterial sulfate reduction as well as demonstrated by the presence of sulfide in the pore water. Moreover, the integral approach shows that bacterial sulfate reduction is not the sole process controlling the isotopic composition of dissolved sulfate in the pore water. The calculated apparent enrichment factor (ɛ = -22‰) for sulfur isotopes from the δ(34)S vs. sulfate mass loss was significantly smaller than required to produce the observed difference in δ(34)S between sulfate and sulfide. It indicated some potential processes superimposing bacterial sulfate reduction, such as direct re-oxidation of sulfide to sulfate by oxygen released from plant roots and/or bacterial disproportionation of elemental sulfur. Furthermore, 41% of residual sulfate was calculated to be from sulfide re-oxidation, which demonstrated that the application of stable isotope approach combined with the common hydro-chemical investigations is not only necessary for a general qualitative evaluation of sulfur transformations in constructed wetlands, but also leads to a quantitative description of intermediate processes. Copyright © 2011 Elsevier Ltd. All rights reserved.

  17. Fe Isotope Fractionation During Fe(III) Reduction to Fe(II)

    NASA Astrophysics Data System (ADS)

    Baker, E. A.; Greene, S.; Hardin, E. E.; Hodierne, C. E.; Rosenberg, A.; John, S.

    2014-12-01

    The redox chemistry of Fe(III) and Fe(II) is tied to a variety of earth processes, including biological, chemical, or photochemical reduction of Fe(III) to Fe(II). Each process may fractionate Fe isotopes, but the magnitudes of the kinetic isotope effects have not been greatly explored in laboratory conditions. Here, we present the isotopic fractionation of Fe during reduction experiments under a variety of experimental conditions including photochemical reduction of Fe(III) bound to EDTA or glucaric acid, and chemical reduction of Fe-EDTA by sodium dithionite, hydroxylamine hydrochloride, Mn(II), and ascorbic acid. A variety of temperatures and pHs were tested. In all experiments, Fe(III) bound to an organic ligand was reduced in the presence of ferrozine. Ferrozine binds with Fe(II), forming a purple complex which allows us to measure the extent of reaction. The absorbance of the experimental solutions was measured over time to determine the Fe(II)-ferrozine concentration and thus the reduction rate. After about 5% of the Fe(III) was reduced, Fe(III)-EDTA and Fe(II)-ferrozine were separated using a C-18 column to which Fe(II)-ferrozine binds. The Fe(II) was eluted and purified through anion exchange chromatography for analysis of δ56Fe by MC-ICPMS. Preliminary results show that temperature and pH both affect reduction rate. All chemical reductants tested reduce Fe(III) at a greater rate as temperature increases. The photochemical reductant EDTA reduces Fe(III) at a greater rate under more acidic conditions. Comparison of the two photochemical reductants shows that glucaric acid reduces Fe(III) significantly faster than EDTA. For chemical reduction, the magnitude of isotopic fractionation depends on the reductant used. Temperature and pH also affect the isotopic fractionation of Fe. Experiments using chemical reductants show that an increase in temperature at low temperatures produces lighter 56Fe ratios, while at high temperatures some reductants produce heavier 56Fe ratios. The magnitude of isotope fractionation is not related to the reduction rate generalized over all reductants. The measured isotopic fractionations produce δ56Fe from -3.82 to +3.05 across all of the reductants tested, highlighting the large impact that redox chemistry may have on fractionating Fe isotopes in the environment.

  18. Management of Sodium-reduced Meals at Worksite Cafeterias: Perceptions, Practices, Barriers, and Needs among Food Service Personnel

    PubMed Central

    Lee, Jounghee; Park, Sohyun

    2015-01-01

    Objectives The sodium content of meals provided at worksite cafeterias is greater than the sodium content of restaurant meals and home meals. The objective of this study was to assess the relationships between sodium-reduction practices, barriers, and perceptions among food service personnel. Methods We implemented a cross-sectional study by collecting data on perceptions, practices, barriers, and needs regarding sodium-reduced meals at 17 worksite cafeterias in South Korea. We implemented Chi-square tests and analysis of variance for statistical analysis. For post hoc testing, we used Bonferroni tests; when variances were unequal, we used Dunnett T3 tests. Results This study involved 104 individuals employed at the worksite cafeterias, comprised of 35 men and 69 women. Most of the participants had relatively high levels of perception regarding the importance of sodium reduction (very important, 51.0%; moderately important, 27.9%). Sodium reduction practices were higher, but perceived barriers appeared to be lower in participants with high-level perception of sodium-reduced meal provision. The results of the needs assessment revealed that the participants wanted to have more active education programs targeting the general population. The biggest barriers to providing sodium-reduced meals were use of processed foods and limited methods of sodium-reduced cooking in worksite cafeterias. Conclusion To make the provision of sodium-reduced meals at worksite cafeterias more successful and sustainable, we suggest implementing more active education programs targeting the general population, developing sodium-reduced cooking methods, and developing sodium-reduced processed foods. PMID:27169011

  19. Sasa-Satsuma higher-order nonlinear Schrödinger equation and its bilinearization and multisoliton solutions.

    PubMed

    Gilson, C; Hietarinta, J; Nimmo, J; Ohta, Y

    2003-07-01

    Higher-order and multicomponent generalizations of the nonlinear Schrödinger equation are important in various applications, e.g., in optics. One of these equations, the integrable Sasa-Satsuma equation, has particularly interesting soliton solutions. Unfortunately, the construction of multisoliton solutions to this equation presents difficulties due to its complicated bilinearization. We discuss briefly some previous attempts and then give the correct bilinearization based on the interpretation of the Sasa-Satsuma equation as a reduction of the three-component Kadomtsev-Petviashvili hierarchy. In the process, we also get bilinearizations and multisoliton formulas for a two-component generalization of the Sasa-Satsuma equation (the Yajima-Oikawa-Tasgal-Potasek model), and for a (2+1)-dimensional generalization.

  20. 77 FR 58380 - General Services Administration Acquisition Regulation; Submission for OMB Review; Price...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-20

    ...] General Services Administration Acquisition Regulation; Submission for OMB Review; Price Reductions Clause... requirement regarding the GSAR Price Reductions Clause. A notice was published in the Federal Register at 76... identified by Information Collection 3090- 0235, Price Reduction Clause, by any of the following methods...

  1. Diagnosing Crime and Diagnosing Disease: Bias Reduction Strategies in the Forensic and Clinical Sciences.

    PubMed

    Lockhart, Joseph J; Satya-Murti, Saty

    2017-11-01

    Cognitive effort is an essential part of both forensic and clinical decision-making. Errors occur in both fields because the cognitive process is complex and prone to bias. We performed a selective review of full-text English language literature on cognitive bias leading to diagnostic and forensic errors. Earlier work (1970-2000) concentrated on classifying and raising bias awareness. Recently (2000-2016), the emphasis has shifted toward strategies for "debiasing." While the forensic sciences have focused on the control of misleading contextual cues, clinical debiasing efforts have relied on checklists and hypothetical scenarios. No single generally applicable and effective bias reduction strategy has emerged so far. Generalized attempts at bias elimination have not been particularly successful. It is time to shift focus to the study of errors within specific domains, and how to best communicate uncertainty in order to improve decision making on the part of both the expert and the trier-of-fact. © 2017 American Academy of Forensic Sciences.

  2. Assessment of Chicken Carcass Microbiome Responses During Processing in the Presence of Commercial Antimicrobials Using a Next Generation Sequencing Approach

    PubMed Central

    Ae Kim, Sun; Hong Park, Si; In Lee, Sang; Owens, Casey M.; Ricke, Steven C.

    2017-01-01

    The purpose of this study was to 1) identify microbial compositional changes on chicken carcasses during processing, 2) determine the antimicrobial efficacy of peracetic acid (PAA) and Amplon (blend of sulfuric acid and sodium sulfate) at a poultry processing pilot plant scale, and 3) compare microbial communities between chicken carcass rinsates and recovered bacteria from media. Birds were collected from each processing step and rinsates were applied to estimate aerobic plate count (APC) and Campylobacter as well as Salmonella prevalence. Microbiome sequencing was utilized to identify microbial population changes over processing and antimicrobial treatments. Only the PAA treatment exhibited significant reduction of APC at the post chilling step while both Amplon and PAA yielded detectable Campylobacter reductions at all steps. Based on microbiome sequencing, Firmicutes were the predominant bacterial group at the phyla level with over 50% frequency in all steps while the relative abundance of Proteobacteria decreased as processing progressed. Overall microbiota between rinsate and APC plate microbial populations revealed generally similar patterns at the phyla level but they were different at the genus level. Both antimicrobials appeared to be effective on reducing problematic bacteria and microbiome can be utilized to identify optimal indicator microorganisms for enhancing product quality. PMID:28230180

  3. On a new ironmaking process to produce hydrogen and reduce energy consumption

    NASA Astrophysics Data System (ADS)

    Corbari, Rodrigo

    The primary purpose of the present work is to compute the volume and composition of the products of a theoretical charring unit for high volatile coals. In particular, the compositions of volatile gas and char and the hydrogen yield of the process. The volume of oxygen necessary to supply the energy for the process was also calculated. The model consists of materials and energy balance equations and local thermodynamic equilibrium. The model was combined with experimental results relating the effect of temperature on the extent of devolatilization and chemistry evolution of coal. Results of the model indicated that temperature plays a major role defining the quantities and composition of charring products. The H2 concentration of the volatile gas increased from about 16vol% at 700°C to 47vol% at 900°C, leveling off at approximately 52vol% at 1100°C. The hydrogen yield of the process increased from 7 to 60 percent at 700°C and 1100°C respectively. For a typical high volatile coal considered, the volume of gas generated varied from about 210 to 780 liters/kg-coal(STP) according to temperature and fraction of solids combusted. The char becomes enriched in carbon and depleted in hydrogen as temperature is increased. As much as 97 percent of the hydrogen in coal is removed at 1100°C. In the second part of this study, the kinetics of reduction of iron oxide fines with simulated smelter gas was experimentally studied by thermogravimetry. An equimolar CO/CO2 mixture was selected to simulate the off-gas of a smelter operating with char at 50 percent post combustion. Reduction temperatures ranged from 590°C to 1000°C. Under these conditions, reduction was limited to wustite. Results indicated that the reduction kinetics and dominating reaction mechanism varied with temperature, extent of reduction and type of iron oxide employed. Reduction from hematite to wustite proceeded in two consecutive reaction steps with magnetite as an intermediate oxide. The first reduction step, hematite to magnetite, was fast and controlled by external gas mass transfer independently of type of iron oxide and temperature employed in this work. The second reduction step, magnetite to wustite, was the overall reaction controlling step. The reduction mechanism varied with temperature and type of iron oxide. For moderately porous oxide fines (VALE and Taconite ores), the magnetite to wustite reduction followed a uniform internal reaction regime, where the chemical reaction at the gas-solid surface is the slowest step. For highly porous oxide (PAH), the magnetite to wustite reduction step was controlled by external gas mass transfer above 700°C. Below that, a mixed regime involving external gas mass transfer and limited mixed control, which comprises pore diffusion and chemical reaction, took place. The rate equations for this mixed control reaction mechanism were developed and the limited mixed control rate constant (klm) was computed. For denser oxides under uniform internal reaction, the product of the rate constant and pore surface area (k·S) was calculated. The final part of this research focused on the study of the mechanisms contributing for the distribution of sulfur in the smelter process. A methodology was developed for this purpose, which computes the sulfur concentration and distribution between the metal, slag and gas phases of the smelter for selected case scenarios. The model assumed the smelter as an ideal continuous stirred reactor under steady state conditions. Sulfur in the gas phase resulted from slag desulfurization by reaction with gas and the direct transfer of sulfur from coal or char. In general, it was found that a large fraction of sulfur leaves the smelter with the gas when coal or char is the only sulfur input to the process. However, the predominant mechanism for transfer of sulfur into the gas depended on process operating conditions. The effect of recycling sulfur back into the smelter was also evaluated. This is important when sulfur leaving with the smelter gas is captured by pre-reduced iron oxide or by dust particles and re-introduced in the process. In general, the more sulfur is recycled into the smelter, the higher the metal and slag sulfur concentration. However, the increasing sulfur content of metal and slag when sulfur is recycled may be partially counter-balanced by the use of char in place of coal. (Abstract shortened by UMI.)

  4. Reducing resistance and denial by exercising ambivalence during the treatment of addiction.

    PubMed

    Shaffer, H J; Simoneau, G

    2001-01-01

    Stage change models and motivational enhancement therapies have significantly influenced the therapeutic tactics clinicians employ in the treatment of addictive behaviors. While motivational enhancement strategies have addressed client ambivalence to increase motivation to change, this article suggests that focusing on ambivalence during treatment has even wider clinical utility than previously thought. Resistance reduction concentrates on exercising ambivalence without an investment in clients changing, thereby strengthening client tolerance for ambivalent thoughts and feelings. Exercising ambivalence reduces resistance to treatment and change by validating a wide array of possible outcomes through detailed exploration of how a behavior pattern works for a client. Since resistance reduction does not require clients to want to change for therapy to progress, exploring the decision-making process becomes paramount. A general discussion of the resistance reduction model, ambivalence, and how clients present for treatment precedes clinical case examples.

  5. Evaporation and air-stripping to assess and reduce ethanolamines toxicity in oily wastewater.

    PubMed

    Libralato, G; Ghirardini, A Volpi; Avezzù, F

    2008-05-30

    Toxicity from industrial oily wastewater remains a problem even after conventional activated sludge treatment process, because of the persistence of some toxicant compounds. This work verified the removal efficiency of organic and inorganic pollutants and the effects of evaporation and air-stripping techniques on oily wastewater toxicity reduction. In a lab-scale plant, a vacuum evaporation procedure at three different temperatures and an air-stripping stage were tested on oily wastewater. Toxicity reduction/removal was observed at each treatment step via Microtox bioassay. A case study monitoring real scale evaporation was also done in a full-size wastewater treatment plant (WWTP). To implement part of a general project of toxicity reduction evaluation, additional investigations took into account the monoethanolamine (MEA), diethanolamine (DEA) and triethanolamine (TEA) role in toxicity definition after the evaporation phase, both as pure substances and mixtures. Only MEA and TEA appeared to contribute towards effluent toxicity.

  6. Comparing Binaural Pre-processing Strategies III

    PubMed Central

    Warzybok, Anna; Ernst, Stephan M. A.

    2015-01-01

    A comprehensive evaluation of eight signal pre-processing strategies, including directional microphones, coherence filters, single-channel noise reduction, binaural beamformers, and their combinations, was undertaken with normal-hearing (NH) and hearing-impaired (HI) listeners. Speech reception thresholds (SRTs) were measured in three noise scenarios (multitalker babble, cafeteria noise, and single competing talker). Predictions of three common instrumental measures were compared with the general perceptual benefit caused by the algorithms. The individual SRTs measured without pre-processing and individual benefits were objectively estimated using the binaural speech intelligibility model. Ten listeners with NH and 12 HI listeners participated. The participants varied in age and pure-tone threshold levels. Although HI listeners required a better signal-to-noise ratio to obtain 50% intelligibility than listeners with NH, no differences in SRT benefit from the different algorithms were found between the two groups. With the exception of single-channel noise reduction, all algorithms showed an improvement in SRT of between 2.1 dB (in cafeteria noise) and 4.8 dB (in single competing talker condition). Model predictions with binaural speech intelligibility model explained 83% of the measured variance of the individual SRTs in the no pre-processing condition. Regarding the benefit from the algorithms, the instrumental measures were not able to predict the perceptual data in all tested noise conditions. The comparable benefit observed for both groups suggests a possible application of noise reduction schemes for listeners with different hearing status. Although the model can predict the individual SRTs without pre-processing, further development is necessary to predict the benefits obtained from the algorithms at an individual level. PMID:26721922

  7. Current status of solar cell performance of unconventional silicon sheets

    NASA Technical Reports Server (NTRS)

    Yoo, H. I.; Liu, J. K.

    1981-01-01

    It is pointed out that activities in recent years directed towards reduction in the cost of silicon solar cells for terrestrial photovoltaic applications have resulted in impressive advancements in the area of silicon sheet formation from melt. The techniques used in the process of sheet formation can be divided into two general categories. All approaches in one category require subsequent ingot wavering. The various procedures of the second category produce silicon in sheet form. The performance of baseline solar cells is discussed. The baseline process included identification marking, slicing to size, and surface treatment (etch-polishing) when needed. Attention is also given to the performance of cells with process variations, and the effects of sheet quality on performance and processing.

  8. [CMACPAR an modified parallel neuro-controller for control processes].

    PubMed

    Ramos, E; Surós, R

    1999-01-01

    CMACPAR is a Parallel Neurocontroller oriented to real time systems as for example Control Processes. Its characteristics are mainly a fast learning algorithm, a reduced number of calculations, great generalization capacity, local learning and intrinsic parallelism. This type of neurocontroller is used in real time applications required by refineries, hydroelectric centers, factories, etc. In this work we present the analysis and the parallel implementation of a modified scheme of the Cerebellar Model CMAC for the n-dimensional space projection using a mean granularity parallel neurocontroller. The proposed memory management allows for a significant memory reduction in training time and required memory size.

  9. Reduction in pesticide residue levels in olives by ozonated and tap water treatments and their transfer into olive oil.

    PubMed

    Kırış, Sevilay; Velioglu, Yakup Sedat

    2016-01-01

    The effects of different wash times (2 and 5 min) with tap and ozonated water on the removal of nine pesticides from olives and the transfer ratios of these pesticides during olive oil production were determined. The reliability of the analytical methods was also tested. The applied methods of analysis were found to be suitable based on linearity, trueness, repeatability, selectivity and limit of quantification all the pesticides tested. All tap and ozonated water wash cycles removed a significant quantity of the pesticides from the olives, with a few exceptions. Generally, extending the wash time increased the pesticide reduction with ozonated water, but did not make significant differences with tap water. During olive oil processing, depending on the processing technique and physicochemical properties of the pesticides, eight of nine pesticides were concentrated into olive oil (processing factor > 1) with almost no significant difference between treatments. Imidacloprid did not pass into olive oil. Ozonated water wash for 5 min reduced chlorpyrifos, β-cyfluthrin, α-cypermethrin and imidacloprid contents by 38%, 50%, 55% and 61% respectively in olives.

  10. Laboratory for Engineering Man/Machine Systems (LEMS): System identification, model reduction and deconvolution filtering using Fourier based modulating signals and high order statistics

    NASA Technical Reports Server (NTRS)

    Pan, Jianqiang

    1992-01-01

    Several important problems in the fields of signal processing and model identification, such as system structure identification, frequency response determination, high order model reduction, high resolution frequency analysis, deconvolution filtering, and etc. Each of these topics involves a wide range of applications and has received considerable attention. Using the Fourier based sinusoidal modulating signals, it is shown that a discrete autoregressive model can be constructed for the least squares identification of continuous systems. Some identification algorithms are presented for both SISO and MIMO systems frequency response determination using only transient data. Also, several new schemes for model reduction were developed. Based upon the complex sinusoidal modulating signals, a parametric least squares algorithm for high resolution frequency estimation is proposed. Numerical examples show that the proposed algorithm gives better performance than the usual. Also, the problem was studied of deconvolution and parameter identification of a general noncausal nonminimum phase ARMA system driven by non-Gaussian stationary random processes. Algorithms are introduced for inverse cumulant estimation, both in the frequency domain via the FFT algorithms and in the domain via the least squares algorithm.

  11. The effect of multi-channel wide dynamic range compression, noise reduction, and the directional microphone on horizontal localization performance in hearing aid wearers.

    PubMed

    Keidser, Gitte; Rohrseitz, Kristin; Dillon, Harvey; Hamacher, Volkmar; Carter, Lyndal; Rass, Uwe; Convery, Elizabeth

    2006-10-01

    This study examined the effect that signal processing strategies used in modern hearing aids, such as multi-channel WDRC, noise reduction, and directional microphones have on interaural difference cues and horizontal localization performance relative to linear, time-invariant amplification. Twelve participants were bilaterally fitted with BTE devices. Horizontal localization testing using a 360 degrees loudspeaker array and broadband pulsed pink noise was performed two weeks, and two months, post-fitting. The effect of noise reduction was measured with a constant noise present at 80 degrees azimuth. Data were analysed independently in the left/right and front/back dimension and showed that of the three signal processing strategies, directional microphones had the most significant effect on horizontal localization performance and over time. Specifically, a cardioid microphone could decrease front/back errors over time, whereas left/right errors increased when different microphones were fitted to left and right ears. Front/back confusions were generally prominent. Objective measurements of interaural differences on KEMAR explained significant shifts in left/right errors. In conclusion, there is scope for improving the sense of localization in hearing aid users.

  12. A General, Concise Strategy that Enables Collective Total Syntheses of over 50 Protoberberine and Five Aporhoeadane Alkaloids within Four to Eight Steps.

    PubMed

    Zhou, Shiqiang; Tong, Rongbiao

    2016-05-17

    A concise, catalytic, and general strategy that allowed efficient total syntheses of 22 natural 13-methylprotoberberines within four steps for each molecule is reported. This synthesis represents the most efficient and shortest route to date, featuring three catalytic processes: CuI-catalyzed redox-A(3) reaction, Pd-catalyzed reductive carbocyclization, and PtO2 -catalyzed hydrogenation. Importantly, this new strategy to the tetracyclic framework has also been applied to the collective concise syntheses of >30 natural protoberberines (without 13-methyl group) and five aporhoeadane alkaloids. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. The impact of pay-for-performance on quality of care for minority patients.

    PubMed

    Epstein, Arnold M; Jha, Ashish K; Orav, E John

    2014-10-01

    To determine whether racial disparities in process quality and outcomes of care change under hospital pay-for-performance. Retrospective cohort study comparing the change in racial disparities in process quality and outcomes of care between 2004 and 2008 in hospitals participating in the Premier Hospital Quality Incentive Demonstration versus control hospitals. Using patient-level Hospital Quality Alliance (HQA) data, we identified 226,096 patients in Premier hospitals, which were subject to pay-for-performance (P4P) contracts and 1,607,575 patients at control hospitals who had process of care measured during hospitalization for acute myocardial infarction (AMI), congestive heart failure (CHF), or pneumonia. We additionally identified 123,241 Medicare patients in Premier hospitals and 995,107 in controls who were hospitalized for AMI, CHF, pneumonia, or coronary artery bypass graft (CABG) surgery. We then compared HQA process quality indicators for AMI, CHF, and pneumonia between P4P and control hospitals, as well as risk-adjusted mortality rates for AMI, CHF, pneumonia, and CABG. Black patients initially had lower performance on process quality indicators in both Premier and non-Premier hospitals. The racial gap decreased over time in both groups; the reduction in the gap in Premier hospitals was greater than the gap reduction in non-Premier hospitals for AMI patients. During the study period, mortality generally decreased for blacks relative to whites for AMI, CHF, and pneumonia in both Premier and non-Premier hospitals, with the relative reduction for blacks greatest in Premier hospitals for CHF. Our results show no evidence of a deleterious impact of P4P in the Premier HQID on racial disparities in process quality or outcomes.

  14. Lightning Arrestor Connectors Production Readiness

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marten, Steve; Linder, Kim; Emmons, Jim

    2008-10-20

    The Lightning Arrestor Connector (LAC), part “M”, presented opportunities to improve the processes used to fabricate LACs. The A## LACs were the first production LACs produced at the KCP, after the product was transferred from Pinnellas. The new LAC relied on the lessons learned from the A## LACs; however, additional improvements were needed to meet the required budget, yield, and schedule requirements. Improvement projects completed since 2001 include Hermetic Connector Sealing Improvement, Contact Assembly molding Improvement, development of a second vendor for LAC shells, general process improvement, tooling improvement, reduction of the LAC production cycle time, and documention of themore » LAC granule fabrication process. This report summarizes the accomplishments achieved in improving the LAC Production Readiness.« less

  15. Feed-back between geriatric syndromes: general system theory in geriatrics.

    PubMed

    Musso, Carlos G; Núñez, Juan F Macías

    2006-01-01

    Geriatrics has described three entities: confusional syndrome, incontinente and gait disorders, calling them geriatric giants. Aging process also induces changes in renal physiology such as glomerular filtration rate reduction, and alteration in water and electrolytes handling. These ageing renal changes have been named as nephrogeriatric giants. These two groups of giants, geriatric and nephrogeriatric, can predispose and potentiate each other leading old people to fatal outcomes. These phenomenon of feed-back between these geriatric syndromes has its roots in the loss of complexity that the ageing process has. Complexity means that all the body systems work harmoniously. The process of senescence weakens this coordination among systems undermining complexity and making the old person frail.

  16. Should breast reduction surgery be rationed? A comparison of the health status of patients before and after treatment: postal questionnaire survey.

    PubMed

    Klassen, A; Fitzpatrick, R; Jenkinson, C; Goodacre, T

    1996-08-24

    To assess the health status of patients before and after breast reduction surgery and to make comparisons with the health status of women in the general population. Postal questionnaire survey sent to patients before and six months after surgery. The three plastic surgery departments in the Oxford Regional Health Authority, during April to August 1993. 166 women (over the age of 16 years) referred for breast reduction; scores from the "short form 36" (SF-36) health questionnaire completed by women in the 1991-2 Oxford healthy life survey. Health status of breast reduction patients before and after surgery as assessed by the SF-36, the 28 item general health questionnaire, and Rosenberg's self esteem scale; comparisons between the health status of breast reduction patients and that of women in the general population; outcome of surgery as assessed retrospectively by patients. Differences between the health status of breast reduction patients and that of women in the general population were detected by the SF-36 both before and after surgery. Breast reduction surgery produced substantial change in patients' physical, social, and psychological function. The proportion of cases of possible psychiatric morbidity according to the general health questionnaire fell from 41% (22/54) before surgery to 11% (6/54) six months after treatment. Eighty six per cent (50/58) of patients expressed great satisfaction with the surgical result postoperatively. The study provides empirical evidence that supports the inclusion of breast reduction surgery in NHS purchasing contracts.

  17. Should breast reduction surgery be rationed? A comparison of the health status of patients before and after treatment: postal questionnaire survey.

    PubMed Central

    Klassen, A.; Fitzpatrick, R.; Jenkinson, C.; Goodacre, T.

    1996-01-01

    OBJECTIVES: To assess the health status of patients before and after breast reduction surgery and to make comparisons with the health status of women in the general population. DESIGN: Postal questionnaire survey sent to patients before and six months after surgery. SETTING: The three plastic surgery departments in the Oxford Regional Health Authority, during April to August 1993. SUBJECTS: 166 women (over the age of 16 years) referred for breast reduction; scores from the "short form 36" (SF-36) health questionnaire completed by women in the 1991-2 Oxford healthy life survey. MAIN OUTCOME MEASURES: Health status of breast reduction patients before and after surgery as assessed by the SF-36, the 28 item general health questionnaire, and Rosenberg's self esteem scale; comparisons between the health status of breast reduction patients and that of women in the general population; outcome of surgery as assessed retrospectively by patients. RESULTS: Differences between the health status of breast reduction patients and that of women in the general population were detected by the SF-36 both before and after surgery. Breast reduction surgery produced substantial change in patients' physical, social, and psychological function. The proportion of cases of possible psychiatric morbidity according to the general health questionnaire fell from 41% (22/54) before surgery to 11% (6/54) six months after treatment. Eighty six per cent (50/58) of patients expressed great satisfaction with the surgical result postoperatively. CONCLUSION: The study provides empirical evidence that supports the inclusion of breast reduction surgery in NHS purchasing contracts. PMID:8776311

  18. Efficient Robust Optimization of Metal Forming Processes using a Sequential Metamodel Based Strategy

    NASA Astrophysics Data System (ADS)

    Wiebenga, J. H.; Klaseboer, G.; van den Boogaard, A. H.

    2011-08-01

    The coupling of Finite Element (FE) simulations to mathematical optimization techniques has contributed significantly to product improvements and cost reductions in the metal forming industries. The next challenge is to bridge the gap between deterministic optimization techniques and the industrial need for robustness. This paper introduces a new and generally applicable structured methodology for modeling and solving robust optimization problems. Stochastic design variables or noise variables are taken into account explicitly in the optimization procedure. The metamodel-based strategy is combined with a sequential improvement algorithm to efficiently increase the accuracy of the objective function prediction. This is only done at regions of interest containing the optimal robust design. Application of the methodology to an industrial V-bending process resulted in valuable process insights and an improved robust process design. Moreover, a significant improvement of the robustness (>2σ) was obtained by minimizing the deteriorating effects of several noise variables. The robust optimization results demonstrate the general applicability of the robust optimization strategy and underline the importance of including uncertainty and robustness explicitly in the numerical optimization procedure.

  19. Changes in EEG spectral power on perception of neutral and emotional words in patients with schizophrenia, their relatives, and healthy subjects from the general population.

    PubMed

    Alfimova, M V; Uvarova, L G

    2008-06-01

    EEG correlates of impairments in the processing of emotiogenic information which might reflect a genetic predisposition to schizophrenia were sought by studying the dynamics of EEG rhythm powers on presentation of neutral and emotional words in 36 patients with schizophrenia, 50 of their unaffected first-degree relatives, and 47 healthy subjects without any inherited predisposition to psychoses. In controls, passive hearing of neutral words produced minimal changes in cortical rhythms, predominantly in the form of increases in the power levels of slow and fast waves, while perception of emotional words was accompanied by generalized reductions in the power of the alpha and beta(1) rhythms and regionally specific suppression of theta and beta(2) activity. Patients and their relatives demonstrated reductions in power of alpha and beta(1) activity, with an increase in delta power on hearing both groups of words. Thus, differences in responses to neutral and emotional words in patients and their relatives were weaker, because of increased reactions to neutral words. These results may identify EEG reflections of pathology of involuntary attention, which is familial and, evidently, inherited in nature. No reduction in reactions to emotiogenic stimuli was seen in patients' families.

  20. Modeling Business Processes in Public Administration

    NASA Astrophysics Data System (ADS)

    Repa, Vaclav

    During more than 10 years of its existence business process modeling became a regular part of organization management practice. It is mostly regarded. as a part of information system development or even as a way to implement some supporting technology (for instance workflow system). Although I do not agree with such reduction of the real meaning of a business process, it is necessary to admit that information technologies play an essential role in business processes (see [1] for more information), Consequently, an information system is inseparable from a business process itself because it is a cornerstone of the general basic infrastructure of a business. This fact impacts on all dimensions of business process management. One of these dimensions is the methodology that postulates that the information systems development provide the business process management with exact methods and tools for modeling business processes. Also the methodology underlying the approach presented in this paper has its roots in the information systems development methodology.

  1. High‐Volume Processed, ITO‐Free Superstrates and Substrates for Roll‐to‐Roll Development of Organic Electronics

    PubMed Central

    Hösel, Markus; Angmo, Dechan; Søndergaard, Roar R.; dos Reis Benatto, Gisele A.; Carlé, Jon E.; Jørgensen, Mikkel

    2014-01-01

    The fabrication of substrates and superstrates prepared by scalable roll‐to‐roll methods is reviewed. The substrates and superstrates that act as the flexible carrier for the processing of functional organic electronic devices are an essential component, and proposals are made about how the general availability of various forms of these materials is needed to accelerate the development of the field of organic electronics. The initial development of the replacement of indium‐tin‐oxide (ITO) for the flexible carrier materials is described and a description of how roll‐to‐roll processing development led to simplification from an initially complex make‐up to higher performing materials through a more simple process is also presented. This process intensification through process simplification is viewed as a central strategy for upscaling, increasing throughput, performance, and cost reduction. PMID:27980893

  2. Reduction of Noise from the J-52 and F-404 Jet Engines During Static Testing Using the Noise Attenuation Device (NAD)

    DTIC Science & Technology

    2009-06-01

    Filters, Order 3, Type 0-C, Optional Range B.2.2 Sound Level Meter Calibration • ISO / IEC 17025 :2005 General requirements for the competence of...noise levels − NCSL -National Conference of Standards Laboratories − ISO - International Standards Organization − IEC - The International...testing and calibration laboratories • ISO 10012:2003 Measurement management systems -- Requirements for measurement processes and measuring

  3. Intermetallic nickel silicide nanocatalyst—A non-noble metal–based general hydrogenation catalyst

    PubMed Central

    Pohl, Marga-Martina; Agapova, Anastasiya

    2018-01-01

    Hydrogenation reactions are essential processes in the chemical industry, giving access to a variety of valuable compounds including fine chemicals, agrochemicals, and pharmachemicals. On an industrial scale, hydrogenations are typically performed with precious metal catalysts or with base metal catalysts, such as Raney nickel, which requires special handling due to its pyrophoric nature. We report a stable and highly active intermetallic nickel silicide catalyst that can be used for hydrogenations of a wide range of unsaturated compounds. The catalyst is prepared via a straightforward procedure using SiO2 as the silicon atom source. The process involves thermal reduction of Si–O bonds in the presence of Ni nanoparticles at temperatures below 1000°C. The presence of silicon as a secondary component in the nickel metal lattice plays the key role in its properties and is of crucial importance for improved catalytic activity. This novel catalyst allows for efficient reduction of nitroarenes, carbonyls, nitriles, N-containing heterocycles, and unsaturated carbon–carbon bonds. Moreover, the reported catalyst can be used for oxidation reactions in the presence of molecular oxygen and is capable of promoting acceptorless dehydrogenation of unsaturated N-containing heterocycles, opening avenues for H2 storage in organic compounds. The generality of the nickel silicide catalyst is demonstrated in the hydrogenation of over a hundred of structurally diverse unsaturated compounds. The wide application scope and high catalytic activity of this novel catalyst make it a nice alternative to known general hydrogenation catalysts, such as Raney nickel and noble metal–based catalysts. PMID:29888329

  4. Intermetallic nickel silicide nanocatalyst-A non-noble metal-based general hydrogenation catalyst.

    PubMed

    Ryabchuk, Pavel; Agostini, Giovanni; Pohl, Marga-Martina; Lund, Henrik; Agapova, Anastasiya; Junge, Henrik; Junge, Kathrin; Beller, Matthias

    2018-06-01

    Hydrogenation reactions are essential processes in the chemical industry, giving access to a variety of valuable compounds including fine chemicals, agrochemicals, and pharmachemicals. On an industrial scale, hydrogenations are typically performed with precious metal catalysts or with base metal catalysts, such as Raney nickel, which requires special handling due to its pyrophoric nature. We report a stable and highly active intermetallic nickel silicide catalyst that can be used for hydrogenations of a wide range of unsaturated compounds. The catalyst is prepared via a straightforward procedure using SiO 2 as the silicon atom source. The process involves thermal reduction of Si-O bonds in the presence of Ni nanoparticles at temperatures below 1000°C. The presence of silicon as a secondary component in the nickel metal lattice plays the key role in its properties and is of crucial importance for improved catalytic activity. This novel catalyst allows for efficient reduction of nitroarenes, carbonyls, nitriles, N-containing heterocycles, and unsaturated carbon-carbon bonds. Moreover, the reported catalyst can be used for oxidation reactions in the presence of molecular oxygen and is capable of promoting acceptorless dehydrogenation of unsaturated N-containing heterocycles, opening avenues for H 2 storage in organic compounds. The generality of the nickel silicide catalyst is demonstrated in the hydrogenation of over a hundred of structurally diverse unsaturated compounds. The wide application scope and high catalytic activity of this novel catalyst make it a nice alternative to known general hydrogenation catalysts, such as Raney nickel and noble metal-based catalysts.

  5. Harm Reduction Agencies as a Potential Site for Buprenorphine Treatment.

    PubMed

    Fox, Aaron D; Chamberlain, Adam; Frost, Taeko; Cunningham, Chinazo O

    2015-01-01

    Harm reduction agencies complement addiction treatment by providing diverse services that improve the health of people who use drugs. Buprenorphine maintenance treatment (BMT) is an effective opioid addiction treatment that may be provided from flexible settings, potentially including harm reduction agencies. This study investigated attitudes toward different potential sites for BMT (harm reduction agencies, general medical clinics, and drug treatment programs) among harm reduction clients. Using computer-based interviews, participants indicated preferred potential site for BMT (harm reduction agency, drug treatment program, or general medical clinic), interest in BMT by potential site, motivation for treatment, and barriers to BMT. Multivariable logistic regression was used to determine factors associated with harm reduction agency preference. Of 102 opioid users, the most preferred potential site for BMT was a harm reduction agency (51%), whereas fewer preferred general medical clinics (13%), drug treatment programs (12%), or were not interested in BMT (25%). In multivariable analysis, experiencing ≥1 barrier to BMT was strongly associated with preferring harm reduction agencies (adjusted odds ratio [aOR] = 3.39, 95% confidence interval [CI]: 1.00-11.43). The potential to initiate BMT at harm reduction agencies is highly favorable among harm reduction clients, especially among those experiencing barriers to BMT. Offering BMT at harm reduction agencies could improve access to treatment, but studies are needed to determine safety and efficacy of this approach.

  6. Influence of calcium on microbial reduction of solid phase uranium(VI).

    PubMed

    Liu, Chongxuan; Jeon, Byong-Hun; Zachara, John M; Wang, Zheming

    2007-08-15

    The effect of calcium on the dissolution and microbial reduction of a representative solid phase uranyl [U(VI)], sodium boltwoodite (NaUO(2)SiO(3)OH . 1.5H(2)O), was investigated to evaluate the rate-limiting step of microbial reduction of the solid phase U(VI). Microbial reduction experiments were performed in a culture of a dissimilatory metal-reducing bacterium (DMRB), Shewanella oneidensis strain MR-1, in a bicarbonate medium with lactate as electron donor at pH 6.8 buffered with PIPES. Calcium increased the rate of Na-boltwoodite dissolution and U(VI) bioavailability by increasing its solubility through the formation of a ternary aqueous calcium-uranyl-carbonate species. The ternary species, however, decreased the rates of microbial reduction of aqueous U(VI). Laser-induced fluorescence spectroscopy (LIFS) and transmission electron microscopy (TEM) collectively revealed that microbial reduction of solid phase U(VI) was a sequentially coupled process of Na-boltwoodite dissolution, U(VI) aqueous speciation, and microbial reduction of dissolved U(VI) to U(IV) that accumulated on bacterial surfaces/periplasm. Under studied experimental conditions, the overall rate of microbial reduction of solid phase U(VI) was limited by U(VI) dissolution reactions in solutions without calcium and limited by microbial reduction in solutions with calcium. Generally, the overall rate of microbial reduction of solid phase U(VI) was determined by the coupling of solid phase U(VI) dissolution, U(VI) aqueous speciation, and microbial reduction of dissolved U(VI) that were all affected by calcium. (c) 2007 Wiley Periodicals, Inc.

  7. Generalized Reduction of Problem Behavior of Young Children with Autism: Building Trans-Situational Interventions

    ERIC Educational Resources Information Center

    Schindler, Holly Reed; Horner, Robert H.

    2005-01-01

    The effects of functional communication training on the generalized reduction of problem behavior with three 4- to 5-year-old children with autism and problem behavior were evaluated. Participants were assessed in primary teaching settings and in three secondary, generalization settings. Through baseline analysis, lower effort interventions in the…

  8. A simulation study of harmonics regeneration in noise reduction for electric and acoustic stimulation.

    PubMed

    Hu, Yi

    2010-05-01

    Recent research results show that combined electric and acoustic stimulation (EAS) significantly improves speech recognition in noise, and it is generally established that access to the improved F0 representation of target speech, along with the glimpse cues, provide the EAS benefits. Under noisy listening conditions, noise signals degrade these important cues by introducing undesired temporal-frequency components and corrupting harmonics structure. In this study, the potential of combining noise reduction and harmonics regeneration techniques was investigated to further improve speech intelligibility in noise by providing improved beneficial cues for EAS. Three hypotheses were tested: (1) noise reduction methods can improve speech intelligibility in noise for EAS; (2) harmonics regeneration after noise reduction can further improve speech intelligibility in noise for EAS; and (3) harmonics sideband constraints in frequency domain (or equivalently, amplitude modulation in temporal domain), even deterministic ones, can provide additional benefits. Test results demonstrate that combining noise reduction and harmonics regeneration can significantly improve speech recognition in noise for EAS, and it is also beneficial to preserve the harmonics sidebands under adverse listening conditions. This finding warrants further work into the development of algorithms that regenerate harmonics and the related sidebands for EAS processing under noisy conditions.

  9. Reduction of Free Edge Peeling Stress of Laminated Composites Using Active Piezoelectric Layers

    PubMed Central

    Huang, Bin; Kim, Heung Soo

    2014-01-01

    An analytical approach is proposed in the reduction of free edge peeling stresses of laminated composites using active piezoelectric layers. The approach is the extended Kantorovich method which is an iterative method. Multiterms of trial function are employed and governing equations are derived by taking the principle of complementary virtual work. The solutions are obtained by solving a generalized eigenvalue problem. By this approach, the stresses automatically satisfy not only the traction-free boundary conditions, but also the free edge boundary conditions. Through the iteration processes, the free edge stresses converge very quickly. It is found that the peeling stresses generated by mechanical loadings are significantly reduced by applying a proper electric field to the piezoelectric actuators. PMID:25025088

  10. SECONDARY GENERAL MOTORS DIESEL ENGINE WITH CONNECTION TO REDUCTION GEAR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    SECONDARY GENERAL MOTORS DIESEL ENGINE WITH CONNECTION TO REDUCTION GEAR BELT DRIVE SYSTEM, LOOKING SOUTH. - Mad River Glen, Single Chair Ski Lift, 62 Mad River Glen Resort Road, Fayston, Washington County, VT

  11. Generalized hydrodynamic reductions of the kinetic equation for a soliton gas

    NASA Astrophysics Data System (ADS)

    Pavlov, M. V.; Taranov, V. B.; El, G. A.

    2012-05-01

    We derive generalized multiflow hydrodynamic reductions of the nonlocal kinetic equation for a soliton gas and investigate their structure. These reductions not only provide further insight into the properties of the new kinetic equation but also could prove to be representatives of a novel class of integrable systems of hydrodynamic type beyond the conventional semi-Hamiltonian framework.

  12. Summary of noise reduction characteristics of typical general aviation materials

    NASA Technical Reports Server (NTRS)

    Roskam, J.; Grosveld, F.; Van Aken, J.

    1979-01-01

    The paper presents the results of a large number of systematic tests to determine noise reduction characteristics of general aviation materials. Effects of material type (metallic and composite), thickness, panel stiffening, vibration damping materials, sound absorption materials and pressurization on noise reduction are included. Several promising methods for reducing cabin interior noise in light airplanes are discussed based on the results.

  13. Modeling sulfate reduction in methane hydrate-bearing continental margin sediments: Does a sulfate-methane transition require anaerobic oxidation of methane?

    USGS Publications Warehouse

    Malinverno, A.; Pohlman, J.W.

    2011-01-01

    The sulfate-methane transition (SMT), a biogeochemical zone where sulfate and methane are metabolized, is commonly observed at shallow depths (1-30 mbsf) in methane-bearing marine sediments. Two processes consume sulfate at and above the SMT, anaerobic oxidation of methane (AOM) and organoclastic sulfate reduction (OSR). Differentiating the relative contribution of each process is critical to estimate methane flux into the SMT, which, in turn, is necessary to predict deeper occurrences of gas hydrates in continental margin sediments. To evaluate the relative importance of these two sulfate reduction pathways, we developed a diagenetic model to compute the pore water concentrations of sulfate, methane, and dissolved inorganic carbon (DIC). By separately tracking DIC containing 12C and 13C, the model also computes ??13C-DIC values. The model reproduces common observations from methane-rich sediments: a well-defined SMT with no methane above and no sulfate below and a ??13C-DIC minimum at the SMT. The model also highlights the role of upward diffusing 13C-enriched DIC in contributing to the carbon isotope mass balance of DIC. A combination of OSR and AOM, each consuming similar amounts of sulfate, matches observations from Site U1325 (Integrated Ocean Drilling Program Expedition 311, northern Cascadia margin). Without AOM, methane diffuses above the SMT, which contradicts existing field data. The modeling results are generalized with a dimensional analysis to the range of SMT depths and sedimentation rates typical of continental margins. The modeling shows that AOM must be active to establish an SMT wherein methane is quantitatively consumed and the ??13C-DIC minimum occurs. The presence of an SMT generally requires active AOM. Copyright 2011 by the American Geophysical Union.

  14. Selective catalytic two-step process for ethylene glycol from carbon monoxide

    PubMed Central

    Dong, Kaiwu; Elangovan, Saravanakumar; Sang, Rui; Spannenberg, Anke; Jackstell, Ralf; Junge, Kathrin; Li, Yuehui; Beller, Matthias

    2016-01-01

    Upgrading C1 chemicals (for example, CO, CO/H2, MeOH and CO2) with C–C bond formation is essential for the synthesis of bulk chemicals. In general, these industrially important processes (for example, Fischer Tropsch) proceed at drastic reaction conditions (>250 °C; high pressure) and suffer from low selectivity, which makes high capital investment necessary and requires additional purifications. Here, a different strategy for the preparation of ethylene glycol (EG) via initial oxidative coupling and subsequent reduction is presented. Separating coupling and reduction steps allows for a completely selective formation of EG (99%) from CO. This two-step catalytic procedure makes use of a Pd-catalysed oxycarbonylation of amines to oxamides at room temperature (RT) and subsequent Ru- or Fe-catalysed hydrogenation to EG. Notably, in the first step the required amines can be efficiently reused. The presented stepwise oxamide-mediated coupling provides the basis for a new strategy for selective upgrading of C1 chemicals. PMID:27377550

  15. In-Situ Formation of Cobalt-Phosphate Oxygen-Evolving Complex-Anchored Reduced Graphene Oxide Nanosheets for Oxygen Reduction Reaction

    PubMed Central

    Zhao, Zhi-Gang; Zhang, Jing; Yuan, Yinyin; Lv, Hong; Tian, Yuyu; Wu, Dan; Li, Qing-Wen

    2013-01-01

    Oxygen conversion process between O2 and H2O by means of electrochemistry or photochemistry has lately received a great deal of attention. Cobalt-phosphate (Co-Pi) catalyst is a new type of cost-effective artificial oxygen-evolving complex (OEC) with amorphous features during photosynthesis. However, can such Co-Pi OEC also act as oxygen reduction reaction (ORR) catalyst in electrochemical processes? The question remains unanswered. Here for the first time we demonstrate that Co-Pi OEC does be rather active for the ORR. Particularly, Co-Pi OEC anchoring on reduced graphite oxide (rGO) nanosheet is shown to possess dramatically improved electrocatalytic activities. Differing from the generally accepted role of rGO as an “electron reservoir”, we suggest that rGO serves as “peroxide cleaner” in enhancing the electrocatalytic behaviors. The present study may bridge the gap between photochemistry and electrochemistry towards oxygen conversion. PMID:23877331

  16. Unexpected mechanochemical complexity in the mechanistic scenarios of disulfide bond reduction in alkaline solution

    NASA Astrophysics Data System (ADS)

    Dopieralski, Przemyslaw; Ribas-Arino, Jordi; Anjukandi, Padmesh; Krupicka, Martin; Marx, Dominik

    2017-02-01

    The reduction of disulfides has a broad importance in chemistry, biochemistry and materials science, particularly those methods that use mechanochemical activation. Here we show, using isotensional simulations, that strikingly different mechanisms govern disulfide cleavage depending on the external force. Desolvation and resolvation processes are found to be crucial, as they have a direct impact on activation free energies. The preferred pathway at moderate forces, a bimolecular SN2 attack of OH- at sulfur, competes with unimolecular C-S bond rupture at about 2 nN, and the latter even becomes barrierless at greater applied forces. Moreover, our study unveils a surprisingly rich reactivity scenario that also includes the transformation of concerted SN2 reactions into pure bond-breaking processes at specific forces. Given that these forces are easily reached in experiments, these insights will fundamentally change our understanding of mechanochemical activation in general, which is now expected to be considerably more intricate than previously thought.

  17. Bio-reduction of free and laden perchlorate by the pure and mixed perchlorate reducing bacteria: Considering the pH and coexisting nitrate.

    PubMed

    Shang, Yanan; Wang, Ziyang; Xu, Xing; Gao, Baoyu; Ren, Zhongfei

    2018-08-01

    Pure bacteria cell (Azospira sp. KJ) and mixed perchlorate reducing bacteria (MPRB) were employed for decomposing the free perchlorate in water as well as the laden perchlorate on surface of quaternary ammonium wheat residuals (QAWR). Results indicated that perchlorate was decomposed by the Azospira sp. KJ prior to nitrate while MPRB was just the reverse. Bio-reduction of laden perchlorate by Azospira sp. KJ was optimal at pH 8.0. In contrast, bio-reduction of laden perchlorate by MPRB was optimal at pH 7.0. Generally, the rate of perchlorate reduction was controlled by the enzyme activity of PRB. In addition, perchlorate recovery (26.0 mg/g) onto bio-regenerated QAWR by MPRB was observed with a small decrease as compared with that (31.1 mg/g) by Azospira sp. KJ at first 48 h. Basically, this study is expected to offer some different ideas on bio-regeneration of perchlorate-saturated adsorbents using biological process, which may provide the economically alternative to conventional methods. Copyright © 2018 Elsevier Ltd. All rights reserved.

  18. Green and facile synthesis of fibrous Ag/cotton composites and their catalytic properties for 4-nitrophenol reduction

    NASA Astrophysics Data System (ADS)

    Li, Ziyu; Jia, Zhigang; Ni, Tao; Li, Shengbiao

    2017-12-01

    Natural cotton, featuring abundant oxygen-containing functional groups, has been utilized as a reductant to synthesize Ag nanoparticles on its surface. Through the facile and environment-friendly reduction process, the fibrous Ag/cotton composite (FAC) was conveniently synthesized. Various characterization techniques including XRD, XPS, TEM, SEM, EDS and FT-IR had been utilized to study the material microstructure and surface properties. The resulting FAC exhibited favorable activity on the catalytic reduction of 4-nitrophenol with high reaction rate. Moreover, the fibrous Ag/cotton composites were capable to form a desirable catalytic mat for catalyzing and simultaneous product separation. Reactants passing through the mat could be catalytically transformed to product, which is of great significance for water treatment. Such catalyst (FAC) was thus expected to have the potential as a highly efficient, cost-effective and eco-friendly catalyst for industrial applications. More importantly, this newly developed synthetic methodology could serve as a general tool to design and synthesize other metal/biomass composites catalysts for a wider range of catalytic applications.

  19. Semi-automated camera trap image processing for the detection of ungulate fence crossing events.

    PubMed

    Janzen, Michael; Visser, Kaitlyn; Visscher, Darcy; MacLeod, Ian; Vujnovic, Dragomir; Vujnovic, Ksenija

    2017-09-27

    Remote cameras are an increasingly important tool for ecological research. While remote camera traps collect field data with minimal human attention, the images they collect require post-processing and characterization before it can be ecologically and statistically analyzed, requiring the input of substantial time and money from researchers. The need for post-processing is due, in part, to a high incidence of non-target images. We developed a stand-alone semi-automated computer program to aid in image processing, categorization, and data reduction by employing background subtraction and histogram rules. Unlike previous work that uses video as input, our program uses still camera trap images. The program was developed for an ungulate fence crossing project and tested against an image dataset which had been previously processed by a human operator. Our program placed images into categories representing the confidence of a particular sequence of images containing a fence crossing event. This resulted in a reduction of 54.8% of images that required further human operator characterization while retaining 72.6% of the known fence crossing events. This program can provide researchers using remote camera data the ability to reduce the time and cost required for image post-processing and characterization. Further, we discuss how this procedure might be generalized to situations not specifically related to animal use of linear features.

  20. Reduction of antiproliferative capacities, cell-based antioxidant capacities and phytochemical contents of common beans and soybeans upon thermal processing.

    PubMed

    Xu, Baojun; Chang, Sam K C

    2011-12-01

    The effects of boiling and steaming processes on the antiproliferative and cellular antioxidant properties, as well as phytochemicals, of two types of common beans (pinto and black beans) and two types of soybeans (yellow and black) were investigated. All thermal-processing methods caused significant (p<0.05) decreases in total phenolic content (TPC), total saponin content (TSC) and phytic acid content (PAC) values in all bean types (except for TPC values in pressure-steamed yellow soybeans) as compared to those of the raw beans. All types of uncooked raw beans exhibited cellular antioxidant activities (CAA) in dose-dependent manners. Black soybeans exhibited the greatest CAA, followed by black beans, pinto beans and yellow soybeans. The CAA of cooked beans were generally diminished or eliminated by thermal processing. The hydrophilic extracts from raw pinto beans, black beans and black soybeans exhibited antiproliferation capacities against human gastric (AGS) and colorectal (SW480) cancer cells in dose-dependent manners. The raw yellow soybeans exhibited dose-dependent antiproliferation activities against the SW480 cells. Most of the cooked beans lost their antiproliferation capacities as observed in the raw beans. These results indicate that different processing methods may have various effects on phytochemical profiles and bioactivities. Overall, thermal processing caused a significant reduction of the health-promotion effects of beans. Copyright © 2011 Elsevier Ltd. All rights reserved.

  1. Automated and Scalable Data Reduction in the textsc{Sofia} Data Processing System

    NASA Astrophysics Data System (ADS)

    Krzaczek, R.; Shuping, R.; Charcos-Llorens, M.; Alles, R.; Vacca, W.

    2015-09-01

    In order to provide suitable data products to general investigators and other end users in a timely manner, the Stratospheric Observatory for Infrared Astronomy SOFIA) has developed a framework supporting the automated execution of data processing pipelines for the various instruments, called the Data Processing System (DPS), see Shuping et al. (2014) for overview). The primary requirement is to process all data collected from a flight within eight hours, allowing data quality assessments and inspections to be made the following day. The raw data collected during a flight requires processing by a number of different software packages and tools unique to each combination of instrument and mode of operation, much of it developed in-house, in order to create data products for use by investigators and other end-users. The requirement to deliver these data products in a consistent, predictable, and performant manner presents a significant challenge for the observatory. Herein we present aspects of the DPS that help to achieve these goals. We discuss how it supports data reduction software written in a variety of languages and environments, its support for new versions and live upgrades to that software and other necessary resources (e.g., calibrations), its accommodation of sudden processing loads through the addition (and eventual removal) of computing resources, and close with an observation of the performance achieved in the first two observing cycles of SOFIA.

  2. Toxicological and chemical characterization of the process stream materials and gas combustion products of an experimental low-btu coal gasifier.

    PubMed

    Benson, J M; Hanson, R L; Royer, R E; Clark, C R; Henderson, R F

    1984-04-01

    The process gas stream of an experimental pressurized McDowell-Wellman stirred-bed low-Btu coal gasifier, and combustion products of the clean gas were characterized as to their mutagenic properties and chemical composition. Samples of aerosol droplets condensed from the gas were obtained at selected positions along the process stream using a condenser train. Mutagenicity was assessed using the Ames Salmonella mammalian microsome mutagenicity assay (TA98, with and without rat liver S9). All materials required metabolic activation to be mutagenic. Droplets condensed from gas had a specific mutagenicity of 6.7 revertants/microgram (50,000 revertants/liter of raw gas). Methylnaphthalene, phenanthrene, chrysene, and nitrogen-containing compounds were positively identified in a highly mutagenic fraction of raw gas condensate. While gas cleanup by the humidifier-tar trap system and Venturi scrubber led to only a small reduction in specific mutagenicity of the cooled process stream material (4.1 revertants/microgram), a significant overall reduction in mutagenicity was achieved (to 2200 revertants/liter) due to a substantial reduction in the concentration of material in the gas. By the end of gas cleanup, gas condensates had no detectable mutagenic activity. Condensates of combustion product gas, which contained several polycyclic aromatic compounds, had a specific mutagenicity of 1.1 revertants/microgram (4.0 revertants/liter). Results indicate that the process stream material is potentially toxic and that care should be taken to limit exposure of workers to the condensed tars during gasifier maintenance and repair and to the aerosolized tars emitted in fugitive emissions. Health risks to the general population resulting from exposure to gas combustion products are expected to be minimal.

  3. Applying integrals of motion to the numerical solution of differential equations

    NASA Technical Reports Server (NTRS)

    Vezewski, D. J.

    1980-01-01

    A method is developed for using the integrals of systems of nonlinear, ordinary, differential equations in a numerical integration process to control the local errors in these integrals and reduce the global errors of the solution. The method is general and can be applied to either scalar or vector integrals. A number of example problems, with accompanying numerical results, are used to verify the analysis and support the conjecture of global error reduction.

  4. UFMulti: A new parallel processing software system for HEP

    NASA Astrophysics Data System (ADS)

    Avery, Paul; White, Andrew

    1989-12-01

    UFMulti is a multiprocessing software package designed for general purpose high energy physics applications, including physics and detector simulation, data reduction and DST physics analysis. The system is particularly well suited for installations where several workstation or computers are connected through a local area network (LAN). The initial configuration of the software is currently running on VAX/VMS machines with a planned extension to ULTRIX, using the new RISC CPUs from Digital, in the near future.

  5. Applying integrals of motion to the numerical solution of differential equations

    NASA Technical Reports Server (NTRS)

    Jezewski, D. J.

    1979-01-01

    A method is developed for using the integrals of systems of nonlinear, ordinary differential equations in a numerical integration process to control the local errors in these integrals and reduce the global errors of the solution. The method is general and can be applied to either scaler or vector integrals. A number of example problems, with accompanying numerical results, are used to verify the analysis and support the conjecture of global error reduction.

  6. Redesigning emergency department patient flows: application of Lean Thinking to health care.

    PubMed

    King, Diane L; Ben-Tovim, David I; Bassham, Jane

    2006-08-01

    To describe in some detail the methods used and outcome of an application of concepts from Lean Thinking in establishing streams for patient flows in a teaching general hospital ED. Detailed understanding was gained through process mapping with staff followed by the identification of value streams (those patients likely to be discharged from the ED, those who were likely to be admitted) and the implementation of a process of seeing those patients that minimized complex queuing in the ED. Streaming had a significant impact on waiting times and total durations of stay in the ED. There was a general flattening of the waiting time across all groups. A slight increase in wait for Triage categories 2 and 3 patients was offset by reductions in wait for Triage category 4 patients. All groups of patients spent significantly less overall time in the department and the average number of patients in the ED at any time decreased. There was a significant reduction in number of patients who do not wait and a slight decrease in access block. The streaming of patients into groups of patients cared for by a specific team of doctors and nurses, and the minimizing of complex queues in this ED by altering the practices in relation to the function of the Australasian Triage Scale improved patient flow, thereby decreasing potential for overcrowding.

  7. 7 CFR 1792.101 - General.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Federally Assisted New Building Construction § 1792.101 General. (a) The Earthquake Hazards Reduction Act of... establishment and maintenance of an effective earthquake hazards reduction program (the National Earthquake... development and implementation of feasible design and construction methods to make structures earthquake...

  8. 7 CFR 1792.101 - General.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Federally Assisted New Building Construction § 1792.101 General. (a) The Earthquake Hazards Reduction Act of... establishment and maintenance of an effective earthquake hazards reduction program (the National Earthquake... development and implementation of feasible design and construction methods to make structures earthquake...

  9. 7 CFR 1792.101 - General.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Federally Assisted New Building Construction § 1792.101 General. (a) The Earthquake Hazards Reduction Act of... establishment and maintenance of an effective earthquake hazards reduction program (the National Earthquake... development and implementation of feasible design and construction methods to make structures earthquake...

  10. 7 CFR 1792.101 - General.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Federally Assisted New Building Construction § 1792.101 General. (a) The Earthquake Hazards Reduction Act of... establishment and maintenance of an effective earthquake hazards reduction program (the National Earthquake... development and implementation of feasible design and construction methods to make structures earthquake...

  11. 7 CFR 1792.101 - General.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Federally Assisted New Building Construction § 1792.101 General. (a) The Earthquake Hazards Reduction Act of... establishment and maintenance of an effective earthquake hazards reduction program (the National Earthquake... development and implementation of feasible design and construction methods to make structures earthquake...

  12. Using Speech Recall in Hearing Aid Fitting and Outcome Evaluation Under Ecological Test Conditions.

    PubMed

    Lunner, Thomas; Rudner, Mary; Rosenbom, Tove; Ågren, Jessica; Ng, Elaine Hoi Ning

    2016-01-01

    In adaptive Speech Reception Threshold (SRT) tests used in the audiological clinic, speech is presented at signal to noise ratios (SNRs) that are lower than those generally encountered in real-life communication situations. At higher, ecologically valid SNRs, however, SRTs are insensitive to changes in hearing aid signal processing that may be of benefit to listeners who are hard of hearing. Previous studies conducted in Swedish using the Sentence-final Word Identification and Recall test (SWIR) have indicated that at such SNRs, the ability to recall spoken words may be a more informative measure. In the present study, a Danish version of SWIR, known as the Sentence-final Word Identification and Recall Test in a New Language (SWIRL) was introduced and evaluated in two experiments. The objective of experiment 1 was to determine if the Swedish results demonstrating benefit from noise reduction signal processing for hearing aid wearers could be replicated in 25 Danish participants with mild to moderate symmetrical sensorineural hearing loss. The objective of experiment 2 was to compare direct-drive and skin-drive transmission in 16 Danish users of bone-anchored hearing aids with conductive hearing loss or mixed sensorineural and conductive hearing loss. In experiment 1, performance on SWIRL improved when hearing aid noise reduction was used, replicating the Swedish results and generalizing them across languages. In experiment 2, performance on SWIRL was better for direct-drive compared with skin-drive transmission conditions. These findings indicate that spoken word recall can be used to identify benefits from hearing aid signal processing at ecologically valid, positive SNRs where SRTs are insensitive.

  13. Reduction Mammoplasty: A Comparison Between Operations Performed by Plastic Surgery and General Surgery.

    PubMed

    Kordahi, Anthony M; Hoppe, Ian C; Lee, Edward S

    2015-01-01

    Reduction mammoplasty is an often-performed procedure by plastic surgeons and increasingly by general surgeons. The question has been posed in both general surgical literature and plastic surgical literature as to whether this procedure should remain the domain of surgical specialists. Some general surgeons are trained in breast reductions, whereas all plastic surgeons receive training in this procedure. The National Surgical Quality Improvement Project provides a unique opportunity to compare the 2 surgical specialties in an unbiased manner in terms of preoperative comorbidities and 30-day postoperative complications. The National Surgical Quality Improvement Project database was queried for the years 2005-2012. Patients were identified as having undergone a reduction mammoplasty by Current Procedural Terminology codes. RESULTS were refined to include only females with an International Classification of Diseases, Ninth Revision, code of 611.1 (hypertrophy of breasts). Information was collected regarding age, surgical specialty performing procedure, body mass index, and other preoperative variables. The outcomes utilized were presence of superficial surgical site infection, presence of deep surgical site infection, presence of wound dehiscence, postoperative respiratory compromise, pulmonary embolism, deep vein thrombosis, perioperative transfusion, operative time, reintubation, reoperation, and length of hospital stay. During this time period, there were 6239 reduction mammaplasties performed within the National Surgical Quality Improvement Project database: 339 by general surgery and 5900 by plastic surgery. No statistical differences were detected between the 2 groups with regard to superficial wound infections, deep wound infections, organ space infections, or wound dehiscence. There were no significant differences noted between within groups with regard to systemic postoperative complications. Patients undergoing a procedure by general surgery were more likely to experience a failure of skin flaps, necessitating a return to the operative room (P < .05). Operative time was longer in procedures performed by general surgery (P < .05). Several important differences appear to exist between reduction mammaplasties performed by general surgery and plastic surgery. A focused training in reduction mammoplasty appears to be beneficial to the patient. The limitations of this study include a lack of long-term follow-up with regard to aesthetic outcome, nipple malposition, nipple sensation, and late wound sequelae.

  14. [Theory of V.A. dogiel on polymerization and oligomerization as a general integration concept].

    PubMed

    Makmaev, Iu V

    2010-01-01

    The theory of V.A. Dogiel on the significance of polymerization and ligomerization processes in the evolution of Protozoa and Metazoa is compared with the paper of I.I. Schmalhauisen (1972) on factors and steps of aromorph evolution. Dogiel's theory is considered as a general integration conception. Four steps are distinguished in the evolution of biological systems: (1) formation of morphofunctional system by units of the lower structural level, (2) polymerization of morphofunctional units of a system, (3) oligomerization of morphofunctional units of system by means of their reduction, uniting, or differentiation, (4) integration and stabilization of a system owing to development of morphofunctional connections between its parts.

  15. Proposal of digital interface for the system of the air conditioner's remote control: analysis of the system of feedback.

    PubMed

    da Silva de Queiroz Pierre, Raisa; Kawada, Tarô Arthur Tavares; Fontes, André Guimarães

    2012-01-01

    Develop a proposal of digital interface for the system of the remote control, that functions as support system during the manipulation of air conditioner adjusted for the users in general, from ergonomic parameters, objectifying the reduction of the problems faced for the user and improving the process. 20 people with questionnaire with both qualitative and quantitative level. Linear Method consists of a sequence of steps in which the input of one of them depends on the output from the previous one, although they are independent. The process of feedback, when necessary, must occur within each step separately.

  16. Graphics Processing Units for HEP trigger systems

    NASA Astrophysics Data System (ADS)

    Ammendola, R.; Bauce, M.; Biagioni, A.; Chiozzi, S.; Cotta Ramusino, A.; Fantechi, R.; Fiorini, M.; Giagu, S.; Gianoli, A.; Lamanna, G.; Lonardo, A.; Messina, A.; Neri, I.; Paolucci, P. S.; Piandani, R.; Pontisso, L.; Rescigno, M.; Simula, F.; Sozzi, M.; Vicini, P.

    2016-07-01

    General-purpose computing on GPUs (Graphics Processing Units) is emerging as a new paradigm in several fields of science, although so far applications have been tailored to the specific strengths of such devices as accelerator in offline computation. With the steady reduction of GPU latencies, and the increase in link and memory throughput, the use of such devices for real-time applications in high-energy physics data acquisition and trigger systems is becoming ripe. We will discuss the use of online parallel computing on GPU for synchronous low level trigger, focusing on CERN NA62 experiment trigger system. The use of GPU in higher level trigger system is also briefly considered.

  17. High Energy Astronomical Data Processing and Analysis via the Internet

    NASA Astrophysics Data System (ADS)

    Valencic, Lynne A.; Snowden, S.; Pence, W.

    2012-01-01

    The HEASARC at NASA Goddard Space Flight Center and the US XMM-Newton GOF has developed Hera, a data processing facility for analyzing high energy astronomical data over the internet. Hera provides all the disk space and computing resources needed to do general processing of and advanced research on publicly available data from High Energy Astrophysics missions. The data and data products are kept on a server at GSFC and can be downloaded to a user's local machine. Further, the XMM-GOF has developed scripts to streamline XMM data reduction. These are available through Hera, and can also be downloaded to a user's local machine. These are free services provided to students, educators, and researchers for educational and research purposes.

  18. Post-fire mulching and soil hydrological response

    NASA Astrophysics Data System (ADS)

    Jordán, Antonio; Zavala, Lorena M.; Gordillo-Rivero, Ángel J.; Muñoz-Rojas, Miriam; Keesstra, Saskia; Cerdà, Artemi

    2017-04-01

    In general, one of the major threats after a forest fire is the increased erosion. This can occur due to the erosive impact of rainfall after a drastic reduction of vegetation cover or to changes in soil surface properties that contribute to enhanced runoff flow. There is a consensus among researchers that one of the best ways to reduce this risk is to apply a mulch cover (straw, shredded wood or other materials) immediately after fire. In this study, we studied the effectiveness of various types of mulch materials for the reduction of runoff and soil loss during the first 3 years after a forest fire, in plots of different sizes, with special attention to water repellency and physical properties of the soil surface. In general, straw mulch reduced both runoff and erosion rate more than other treatments. However, the effect was much more important on larger plots. This may be due to specific processes and impacts on sediment connectivity and surface water flow. Therefore, the effect of the scale seems to be an important factor in the management of burnt soils.

  19. Anelasticity of olivine single crystals investigated by stress-reduction tests and high-angular resolution electron backscatter diffraction

    NASA Astrophysics Data System (ADS)

    Wallis, D.; Hansen, L. N.; Kempton, I.; Wilkinson, A. J.

    2017-12-01

    Geodynamic phenomena, including glacial isostatic adjustment and postseismic deformation, can involve transient deformation in response to changes in differential stress acting on mantle rocks. As such, rheological models of transient deformation are incorporated in predictions of associated processes, including sea-level rise and stress redistribution after earthquakes. However, experimental constraints on rheological models for transient deformation of mantle materials are sparse. In particular, experiments involving stress reductions have been lacking. Moreover, a material's response to a reduction in stress can provide clues to the microphysical processes controlling deformation. To constrain models of transient deformation of mantle rocks we performed stress-reduction tests on single crystals of olivine at 1250-1300°C. Mechanical and piezoelectric actuators controlled constant initial stress during creep. At various strain intervals stress was reduced near-instantaneously using the piezoelectric actuator, inducing both elastic and anelastic (time-dependent) lengthening of the samples. A range of magnitudes of stress reduction were applied, typically unloading 10-90% of the initial stress. High-angular resolution electron backscatter diffraction (HR-EBSD), based on cross-correlation of diffraction patterns, was used to map dislocation density and elastic strain distributions in the recovered samples. Magnitudes of anelastic back-strain increase with increasing magnitudes of stress reduction and show a marked increase when stress reductions exceed 50% of the initial stress, consistent with previous observations in metals and alloys. This observation is inconsistent with the Burgers rheological model commonly used to describe transient behaviour and suggests that the style of rheological behaviour depends on the magnitude of stress change. HR-EBSD maps reveal that the crystal lattices are smoothly curved and generally lack subgrain boundaries and elastic strain heterogeneities. The dependence of the anelastic behaviour on the initial stress, combined with the lack of subgrain boundaries, suggest that the anelastic behaviour is controlled by local interactions between dislocations, rather than resistance imposed by the lattice or subgrain boundaries.

  20. Secrets of the lac operon. Glucose hysteresis as a mechanism in dietary restriction, aging and disease.

    PubMed

    Mobbs, Charles V; Mastaitis, Jason W; Zhang, Minhua; Isoda, Fumiko; Cheng, Hui; Yen, Kelvin

    2007-01-01

    Elevated blood glucose associated with diabetes produces progressive and apparently irreversible damage to many cell types. Conversely, reduction of glucose extends life span in yeast, and dietary restriction reduces blood glucose. Therefore it has been hypothesized that cumulative toxic effects of glucose drive at least some aspects of the aging process and, conversely, that protective effects of dietary restriction are mediated by a reduction in exposure to glucose. The mechanisms mediating cumulative toxic effects of glucose are suggested by two general principles of metabolic processes, illustrated by the lac operon but also observed with glucose-induced gene expression. First, metabolites induce the machinery of their own metabolism. Second, induction of gene expression by metabolites can entail a form of molecular memory called hysteresis. When applied to glucose-regulated gene expression, these two principles suggest a mechanism whereby repetitive exposure to postprandial excursions of glucose leads to an age-related increase in glycolytic capacity (and reduction in beta-oxidation of free fatty acids), which in turn leads to an increased generation of oxidative damage and a decreased capacity to respond to oxidative damage, independent of metabolic rate. According to this mechanism, dietary restriction increases life span and reduces pathology by reducing exposure to glucose and therefore delaying the development of glucose-induced glycolytic capacity.

  1. A process-based approach to characterizing the effect of acute alprazolam challenge on visual paired associate learning and memory in healthy older adults.

    PubMed

    Pietrzak, Robert H; Scott, James Cobb; Harel, Brian T; Lim, Yen Ying; Snyder, Peter J; Maruff, Paul

    2012-11-01

    Alprazolam is a benzodiazepine that, when administered acutely, results in impairments in several aspects of cognition, including attention, learning, and memory. However, the profile (i.e., component processes) that underlie alprazolam-related decrements in visual paired associate learning has not been fully explored. In this double-blind, placebo-controlled, randomized cross-over study of healthy older adults, we used a novel, "process-based" computerized measure of visual paired associate learning to examine the effect of a single, acute 1-mg dose of alprazolam on component processes of visual paired associate learning and memory. Acute alprazolam challenge was associated with a large magnitude reduction in visual paired associate learning and memory performance (d = 1.05). Process-based analyses revealed significant increases in distractor, exploratory, between-search, and within-search error types. Analyses of percentages of each error type suggested that, relative to placebo, alprazolam challenge resulted in a decrease in the percentage of exploratory errors and an increase in the percentage of distractor errors, both of which reflect memory processes. Results of this study suggest that acute alprazolam challenge decreases visual paired associate learning and memory performance by reducing the strength of the association between pattern and location, which may reflect a general breakdown in memory consolidation, with less evidence of reductions in executive processes (e.g., working memory) that facilitate visual paired associate learning and memory. Copyright © 2012 John Wiley & Sons, Ltd.

  2. Preservation of organic matter in nontronite against iron redox cycling.

    NASA Astrophysics Data System (ADS)

    Zeng, Q.

    2015-12-01

    It is generally believed that clay minerals can protect organic matter from degradation in redox active environments, but both biotic and abiotic factors can influence the redox process and thus potentially change the clay-organic associations. However, the specific mechanisms involved in this process remain poorly understood. In this study, a model organic compound, 12-Aminolauric acid (ALA) was selected to intercalate into the structural interlayer of nontronite (an iron-rich smectite, NAu-2) to form an ALA-intercalated NAu-2 composite (ALA-NAu-2). Shawanella putrefaciens CN32 and sodium dithionite were used to reduce structural Fe(III) to Fe(II) in NAu-2 and ALA-NAu-2. The bioreduced ALA-NAu-2 was subsequently re-oxidized by air. The rates and extents of bioreduction and air re-oxidation were determined with wet chemistry methods. ALA release from ALA-NAu-2 via redox process was monitored. Mineralogical changes after iron redox cycle were investigated with X-ray diffraction, infrared spectroscopy, and scanning and transmission electron microscopy. At the beginning stage of bioreduction, S. putrefaciens CN32 reduced Fe(III) from the edges of nontronite and preferentially reduced and dissolved small and poorly crystalline particles, and released ALA, resulting a positive correlation between ALA release and iron reduction extent (<12%). The subsequent bioreduction (reduction extent ranged from 12~30%) and complete air re-oxidation showed no effect on ALA release. These results suggest that released ALA was largely from small and poorly crystalline NAu-2 particles. In contrast to bioreduction, chemical reduction did not exhibit any selectivity in reducing ALA-NAu-2 particles, and a considerable amount of reductive dissolution was responsible for a large amount of ALA release (>80%). Because bacteria are the principal agent for mediating redox process in natural environments, our results demonstrated that the structural interlayer of smectite can serve as a potential shelter to protect organic matter from oxidation.

  3. The handicap process favors exaggerated, rather than reduced, sexual ornaments.

    PubMed

    Tazzyman, Samuel J; Iwasa, Yoh; Pomiankowski, Andrew

    2014-09-01

    Why are traits that function as secondary sexual ornaments generally exaggerated in size compared to the naturally selected optimum, and not reduced? Because they deviate from the naturally selected optimum, traits that are reduced in size will handicap their bearer, and could thus provide an honest signal of quality to a potential mate. Thus if secondary sexual ornaments evolve via the handicap process, current theory suggests that reduced ornamentation should be as frequent as exaggerated ornamentation, but this is not the case. To try to explain this discrepancy, we analyze a simple model of the handicap process. Our analysis shows that asymmetries in costs of preference or ornament with regard to exaggeration and reduction cannot fully explain the imbalance. Rather, the bias toward exaggeration can be best explained if either the signaling efficacy or the condition dependence of a trait increases with size. Under these circumstances, evolution always leads to more extreme exaggeration than reduction: although the two should occur just as frequently, exaggerated secondary sexual ornaments are likely to be further removed from the naturally selected optimum than reduced ornaments. © 2014 The Authors. Evolution published by Wiley Periodicals, Inc. on behalf of The Society for the Study of Evolution.

  4. Oxygen Extraction from Minerals

    NASA Technical Reports Server (NTRS)

    Muscatello, Tony

    2017-01-01

    Oxygen, whether used as part of rocket bipropellant or for astronaut life support, is a key consumable for space exploration and commercialization. In Situ Resource Utilization (ISRU) has been proposed many times as a method for making space exploration more cost effective and sustainable. On planetary and asteroid surfaces the presence of minerals in the regolith that contain oxygen is very common, making them a potential oxygen resource. The majority of research and development for oxygen extraction from minerals has been for lunar regolith although this work would generally be applicable to regolith at other locations in space. This presentation will briefly survey the major methods investigated for oxygen extraction from regolith with a focus on the current status of those methods and possible future development pathways. The major oxygen production methods are (1) extraction from lunar ilmenite (FeTiO3) with either hydrogen or carbon monoxide, (2) carbothermal reduction of iron oxides and silicates with methane, and (3) molten regolith electrolysis (MRE) of silicates. Methods (1) and (2) have also been investigated in a two-step process using CO reduction and carbon deposition followed by carbothermal reduction. All three processes have byproducts that could also be used as resources. Hydrogen or carbon monoxide reduction produce iron metal in small amounts that could potentially be used as construction material. Carbothermal reduction also makes iron metal along with silicon metal and a glass with possible applications. MRE produces iron, silicon, aluminum, titanium, and glass, with higher silicon yields than carbothermal reduction. On Mars and possibly on some moons and asteroids, water is present in the form of mineral hydrates, hydroxyl (-OH) groups on minerals, andor water adsorbed on mineral surfaces. Heating of the minerals can liberate the water which can be electrolyzed to provide a source of oxygen as well. The chemistry of these processes, some key development and demonstration projects, the challenges remaining to be overcome, and possible future directions will be discussed with a goal of increased understanding of these important ISRU technologies and their potential applications to space exploration and settlement.

  5. Biodegradation potential of chlorinated solvents in ground water at the Naval Surface Warfare Center, Louisville, Kentucky, July 1999 to February 2000

    USGS Publications Warehouse

    Vroblesky, Don A.; Bradley, Paul M.; Petkewich, Matthew D.; Casey, Clifton C.

    2001-01-01

    The U.S. Geological Survey, in cooperation with the U.S. Department of the Navy, Southern Division Naval Facilities Engineering Command, investigated the potential for biodegradation of chlorinated solvents in ground water at the Naval Surface Warfare Center (also known as the Naval Ordnance Station, or the station), Louisville, Kentucky. The subsurface down to at least 100 feet at the station is characterized, from shallowest to deepest, by overburden deposits, a shale layer, and limestone. In general, all of the strata are poorly permeable. The permeable zones of the overburden and the limestone make up the overburden aquifer and the bedrock aquifer, respectively. Observed concentrations of redox-sensitive solutes suggest that the predominant anaerobic terminal electron accepting process in the overburden aquifer can shift between iron reduction and sulfate reduction, possibly as a result of rainfall-induced oxidation events. Daughter-product concentrations and laboratory experiments indicate that a variety of mechanisms, including reductive dechlorination and cometabolic oxidation, appear to be actively

  6. SNR Degradation in Undersampled Phase Measurement Systems

    PubMed Central

    Salido-Monzú, David; Meca-Meca, Francisco J.; Martín-Gorostiza, Ernesto; Lázaro-Galilea, José L.

    2016-01-01

    A wide range of measuring applications rely on phase estimation on sinusoidal signals. These systems, where the estimation is mainly implemented in the digital domain, can generally benefit from the use of undersampling to reduce the digitizer and subsequent digital processing requirements. This may be crucial when the application characteristics necessarily imply a simple and inexpensive sensor. However, practical limitations related to the phase stability of the band-pass filter prior digitization establish restrictions to the reduction of noise bandwidth. Due to this, the undersampling intensity is practically defined by noise aliasing, taking into account the amount of signal-to-noise ratio (SNR) reduction caused by it considering the application accuracy requirements. This work analyzes the relationship between undersampling frequency and SNR reduction, conditioned by the stability requirements of the filter that defines the noise bandwidth before digitization. The effect of undersampling is quantified in a practical situation where phase differences are measured by in-phase and quadrature (I/Q) demodulation for an infrared ranging application. PMID:27783033

  7. Chaotic oscillator containing memcapacitor and meminductor and its dimensionality reduction analysis.

    PubMed

    Yuan, Fang; Wang, Guangyi; Wang, Xiaowei

    2017-03-01

    In this paper, smooth curve models of meminductor and memcapacitor are designed, which are generalized from a memristor. Based on these models, a new five-dimensional chaotic oscillator that contains a meminductor and memcapacitor is proposed. By dimensionality reducing, this five-dimensional system can be transformed into a three-dimensional system. The main work of this paper is to give the comparisons between the five-dimensional system and its dimensionality reduction model. To investigate dynamics behaviors of the two systems, equilibrium points and stabilities are analyzed. And the bifurcation diagrams and Lyapunov exponent spectrums are used to explore their properties. In addition, digital signal processing technologies are used to realize this chaotic oscillator, and chaotic sequences are generated by the experimental device, which can be used in encryption applications.

  8. Spacelab user interaction

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The results of the third and final phase of a study undertaken to define means of optimizing the Spacelab experiment data system by interactively manipulating the flow of data were presented. A number of payload applicable interactive techniques and an integrated interaction system for each of two possible payloads are described. These interaction systems have been functionally defined and are accompanied with block diagrams, hardware specifications, software sizing and speed requirements, operational procedures and cost/benefits analysis data for both onboard and ground based system elements. It is shown that accrued benefits are attributable to a reduction in data processing costs obtained by, generally, a considerable reduction in the quantity of data that might otherwise be generated without interaction. One other additional anticipated benefit includes the increased scientific value obtained by the quicker return of all useful data.

  9. Bilateral Breast Reduction Without Opioid Analgesics: A Comparative Study.

    PubMed

    Parsa, Fereydoun Don; Cheng, Justin; Stephan, Brad; Castel, Nikki; Kim, Leslie; Murariu, Daniel; Parsa, Alan A

    2017-09-01

    Breast reduction has traditionally been performed under general anesthesia with adjunct opioid use. However, opioids are associated with a wide variety of adverse effects, including nausea, vomiting, constipation, postoperative sedation, dizziness, and addiction. This study compares bilateral breast reduction using a multimodal opioid-free pain management regimen vs traditional general anesthesia with adjunct opioids. A total of 83 female patients were enrolled in this study. Group 1 includes a retrospective series of 39 patients that underwent breast reduction via general anesthesia with adjunct opioid use. This series was compared to 2 prospective groups of patients who did not receive opioids either preoperatively or intraoperatively. In group 2, twenty-six patients underwent surgery under intravenous sedation and local anesthesia. In group 3, eighteen patients underwent surgery with general anesthesia. All patients in groups 2 and 3 received preoperative gabapentin and celecoxib along with infiltration of local anesthetics during the operation and prior to discharge to the Post-Anesthesia Care Unit (PACU). Primary outcome measures included the duration of surgery, time from end of operation to discharge home, postoperative opioid and antiemetic use, and unplanned postoperative hospitalizations. When compared to group 1, groups 2 and 3 experienced a shorter time from end of operation to discharge home (P < 0.05), fewer unplanned hospital admissions (P < 0.05), and highly significant decrease in postoperative opioid use (P < 0.001). This multimodal approach allows patients to safely undergo opioid-free bilateral breast reduction either under local or general anesthesia as an outpatient. This method resulted in significantly less morbidity, use of opioids postoperatively, as well as unplanned hospital admissions compared to "traditional" breast reduction under general anesthesia with the use of opioids. 3. © 2017 The American Society for Aesthetic Plastic Surgery, Inc. Reprints and permission: journals.permissions@oup.com

  10. Investigation of the reduction process of dopamine using paired pulse voltammetry

    PubMed Central

    Kim, Do Hyoung; Oh, Yoonbae; Shin, Hojin; Blaha, Charles D.; Bennet, Kevin E.; Lee, Kendall H.; Kim, In Young; Jang, Dong Pyo

    2014-01-01

    The oxidation of dopamine (DA) around +0.6V potential in anodic sweep and its reduction around −0.1V in cathodic sweep at a relatively fast scanning rate (300 V/s or greater) have been used for identification of DA oxidation in fast-scan cyclic voltammetry (FSCV). However, compared to the oxidation peak of DA, the reduction peak has not been fully examined in analytical studies, although it has been used as one of the representative features to identify DA. In this study, the reduction process of DA was investigated using paired pulse voltammetry (PPV), which consists of two identical triangle-shaped waveforms, separated by a short interval at the holding potential. Especially, the discrepancies between the magnitude of the oxidation and reduction peaks of DA were investigated based on three factors: (1) the instant desorption of the DA oxidation product (dopamine-o-quinone: DOQ) after production, (2) the effect of the holding potential on the reduction process, and (3) the rate-limited reduction process of DA. For the first test, the triangle waveform FSCV experiment was performed on DA with various scanrates (from 400 to 1000 V/s) and durations of switching potentials of the triangle waveform (from 0.0 to 6.0 ms) in order to vary the duration between the applied oxidation potential at +0.6V and the reduction potential at −0.2V. As a result, the ratio of reduction over oxidation peak current response decreased as the duration became longer. To evaluate the effect of holding potentials during the reduction process, FSCV experiments were conducted with holding potential from 0.0V to −0.8V. We found that more negative holding potentials lead to larger amount of reduction process. For evaluation of the rate-limited reduction process of DA, PPV with a 1Hz repetition rate and various delays (2, 8, 20, 40 and 80ms) between the paired scans were utilized to determine how much reduction process occurred during the holding potential (−0.4V). These tests showed that relatively large amounts of DOQ are reduced to DA during the holding potential. The rate-limited reduction process was also confirmed with the increase of reduction in a lower pH environment. In addition to the mechanism of the reduction process of DA, we found that the differences between the responses of primary and secondary pulses in PPV were mainly dependent on the rate-limited reduction process during the holding potential. In conclusion, the reduction process may be one of the important factors to be considered in the kinetic analysis of DA and other electroactive species in brain tissue and in the design of new types of waveform in FSCV. PMID:24926227

  11. The preparation of tantalum powder using a MR-EMR combination process

    NASA Astrophysics Data System (ADS)

    Yoon, Jae Sik; Kim, Byung Il

    2007-04-01

    In the conventional metallothermic reduction (MR) process used to obtain tantalum powder in batch-type operation, it is difficult to control the morphology and location of the tantalum deposits. In contrast, an electronically mediated reaction (EMR) process is capable of overcoming this difficulty. It has the advantage of being a continuous process, but has the disadvantage of a poor reduction yield. A process known as the MR-EMR combination process is able to overcome the shortcomings of the MR and EMR processes. In this study, an MR-EMR combination process is applied to the production of tantalum powder via sodium reduction of K2TaF7. In the MR-EMR combination process, the total charge passed through an external circuit and the average particle size (FSSS) increase as the reduction temperature increases. In addition, the proportion of fine particles (-325 mesh) decreases as the reduction temperature increasess. The tantalum yield improved from 65 to 74% as the reduction temperature increased. Taking into account the charge, impurities, morphology, particle size and yield, a reduction temperature of 1123 K was found to be optimum for the MR-EMR combination process.

  12. Photonic Integrated Circuits

    NASA Technical Reports Server (NTRS)

    Krainak, Michael; Merritt, Scott

    2016-01-01

    Integrated photonics generally is the integration of multiple lithographically defined photonic and electronic components and devices (e.g. lasers, detectors, waveguides passive structures, modulators, electronic control and optical interconnects) on a single platform with nanometer-scale feature sizes. The development of photonic integrated circuits permits size, weight, power and cost reductions for spacecraft microprocessors, optical communication, processor buses, advanced data processing, and integrated optic science instrument optical systems, subsystems and components. This is particularly critical for small spacecraft platforms. We will give an overview of some NASA applications for integrated photonics.

  13. 78 FR 79727 - Proposed Collection; Comment Request for Revenue Procedure 2004-47

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-31

    ...The Department of the Treasury, as part of its continuing effort to reduce paperwork and respondent burden, invites the general public and other Federal agencies to take this opportunity to comment on proposed and/or continuing information collections, as required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)). Currently, the IRS is soliciting comments concerning relief from ruling process for making late reverse QTIP election.

  14. Considerations with respect to the design of solar photovoltaic power systems for terrestrial applications

    NASA Technical Reports Server (NTRS)

    Berman, P. A.

    1972-01-01

    The various factors involved in the development of solar photovoltaic power systems for terrestrial application are discussed. The discussion covers the tradeoffs, compromises, and optimization studies which must be performed in order to develop a viable terrestrial solar array system. It is concluded that the technology now exists for the fabrication of terrestrial solar arrays but that the economics are prohibitive. Various approaches to cost reduction are presented, and the general requirements for materials and processes to be used are delineated.

  15. Hierarchically Parallelized Constrained Nonlinear Solvers with Automated Substructuring

    NASA Technical Reports Server (NTRS)

    Padovan, Joe; Kwang, Abel

    1994-01-01

    This paper develops a parallelizable multilevel multiple constrained nonlinear equation solver. The substructuring process is automated to yield appropriately balanced partitioning of each succeeding level. Due to the generality of the procedure,_sequential, as well as partially and fully parallel environments can be handled. This includes both single and multiprocessor assignment per individual partition. Several benchmark examples are presented. These illustrate the robustness of the procedure as well as its capability to yield significant reductions in memory utilization and calculational effort due both to updating and inversion.

  16. Metalized, three-dimensional structured oxygen cathode materials for lithium/air batteries and method for making and using the same

    DOEpatents

    Xing, Weibing; Buettner-Garrett, Josh

    2017-04-18

    This disclosure relates generally to cathode materials for electrochemical energy cells, more particularly to metal/air electrochemical energy cell cathode materials containing silver vanadium oxide and methods of making and using the same. The metal/air electrochemical energy cell can be a lithium/air electrochemical energy cell. Moreover the silver vanadium oxide can be a catalyst for one or more of oxidation and reduction processes of the electrochemical energy cell.

  17. Near Term Weight Reduction Potential in a 1977 General Motors B Body Vehicle : final report

    DOT National Transportation Integrated Search

    1978-05-01

    The report presents an analysis of the potential for weight reduction through lightweight material and component substitutions in a 1977 General Motors Corporation B body vehicle. The changes were limited to those that appeared producible in the 1980...

  18. 48 CFR 32.503-6 - Suspension or reduction of payments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 32.503-6 Suspension or reduction of payments. (a) General. The Progress Payments clause provides a Government right to reduce or suspend progress payments, or to increase the liquidation rate, under specified conditions...

  19. Multiphysical FE-analysis of a front-end bending phenomenon in a hot strip mill

    NASA Astrophysics Data System (ADS)

    Ilmola, Joonas; Seppälä, Oskari; Leinonen, Olli; Pohjonen, Aarne; Larkiola, Jari; Jokisaari, Juha; Putaansuu, Eero

    2018-05-01

    In hot steel rolling processes, a slab is generally rolled to a transfer bar in a roughing process and to a strip in a hot strip rolling process. Over several rolling passes the front-end may bend upward or downward due to asymmetrical rolling conditions causing entry problems in the next rolling pass. Many different factors may affect the front-end bending phenomenon and are very challenging to measure. Thus, a customized finite element model is designed and built to simulate the front-end bending phenomenon in a hot strip rolling process. To simulate the functioning of the hot strip mill precisely, automated controlling logic of the mill must be considered. In this paper we studied the effect of roll bite friction conditions and amount of reduction on the front-end bending phenomenon in a hot strip rolling process.

  20. Accelerated numerical processing of electronically recorded holograms with reduced speckle noise.

    PubMed

    Trujillo, Carlos; Garcia-Sucerquia, Jorge

    2013-09-01

    The numerical reconstruction of digitally recorded holograms suffers from speckle noise. An accelerated method that uses general-purpose computing in graphics processing units to reduce that noise is shown. The proposed methodology utilizes parallelized algorithms to record, reconstruct, and superimpose multiple uncorrelated holograms of a static scene. For the best tradeoff between reduction of the speckle noise and processing time, the method records, reconstructs, and superimposes six holograms of 1024 × 1024 pixels in 68 ms; for this case, the methodology reduces the speckle noise by 58% compared with that exhibited by a single hologram. The fully parallelized method running on a commodity graphics processing unit is one order of magnitude faster than the same technique implemented on a regular CPU using its multithreading capabilities. Experimental results are shown to validate the proposal.

  1. Toxics Use Reduction in the Home: Lessons Learned from Household Exposure Studies

    PubMed Central

    Dunagan, Sarah C.; Dodson, Robin E.; Rudel, Ruthann A.; Brody, Julia G.

    2010-01-01

    Workers and fence-line communities have been the first to benefit from the substantial reductions in toxic chemical use and byproducts in industrial production resulting from the Massachusetts Toxics Use Reduction Act (TURA). As TURA motivates reformulation of products as well as retooling of production processes, benefits could extend more broadly to large-scale reductions in everyday exposures for the general population. Household exposure studies, including those conducted by Silent Spring Institute, show that people are exposed to complex mixtures of indoor toxics from building materials and a myriad of consumer products. Pollutants in homes are likely to have multiple health effects because many are classified as endocrine disrupting compounds (EDCs), with the ability to interfere with the body's hormone system. Product-related EDCs measured in homes include phthalates, halogenated flame retardants, and alkylphenols. Silent Spring Institute's chemical analysis of personal care and cleaning products confirms many are potential sources of EDCs, highlighting the need for a more comprehensive toxics use reduction (TUR) approach to reduce those exposures. Toxics use reduction targeted at EDCs in consumer products has the potential to substantially reduce occupational and residential exposures. The lessons that have emerged from household exposure research can inform improved chemicals management policies at the state and national levels, leading to safer products and widespread health and environmental benefits. PMID:21516227

  2. Impact of a Sequential Intervention on Albumin Utilization in Critical Care.

    PubMed

    Lyu, Peter F; Hockenberry, Jason M; Gaydos, Laura M; Howard, David H; Buchman, Timothy G; Murphy, David J

    2016-07-01

    Literature generally finds no advantages in mortality risk for albumin over cheaper alternatives in many settings. Few studies have combined financial and nonfinancial strategies to reduce albumin overuse. We evaluated the effect of a sequential multifaceted intervention on decreasing albumin use in ICU and explore the effects of different strategies. Prospective prepost cohort study. Eight ICUs at two hospitals in an academic healthcare system. Adult patients admitted to study ICUs from September 2011 to August 2014 (n = 22,004). Over 2 years, providers in study ICUs participated in an intervention to reduce albumin use involving monthly feedback and explicit financial incentives in the first year and internal guidelines and order process changes in the second year. Outcomes measured were albumin orders per ICU admission, direct albumin costs, and mortality. Mean (SD) utilization decreased 37% from 2.7 orders (6.8) per admission during the baseline to 1.7 orders (4.6) during the intervention (p < 0.001). Regression analysis revealed that the intervention was independently associated with 0.9 fewer orders per admission, a 42% relative decrease. This adjusted effect consisted of an 18% reduction in the probability of using any albumin (p < 0.001) and a 29% reduction in the number of orders per admission among patients receiving any (p < 0.001). Secondary analysis revealed that probability reductions were concurrent with internal guidelines and order process modification while reductions in quantity occurred largely during the financial incentives and feedback period. Estimated cost savings totaled $2.5M during the 2-year intervention. There was no significant difference in ICU or hospital mortality between baseline and intervention. A sequential intervention achieved significant reductions in ICU albumin use and cost savings without changes in patient outcomes, supporting the combination of financial and nonfinancial strategies to align providers with evidence-based practices.

  3. Recycling of high purity selenium from CIGS solar cell waste materials

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gustafsson, Anna M.K., E-mail: anna.gustafsson@chalmers.se; Foreman, Mark R.StJ.; Ekberg, Christian

    Highlights: • A new method for recycling of selenium from CIGS solar cell materials is presented. • Separation of selenium as selenium dioxide after heating in oxygen atmosphere. • Complete selenium separation after oxidation of <63 μm particles at 800 °C for 1 h. • After reduction of selenium dioxide the selenium purity was higher than 99.999 wt%. - Abstract: Copper indium gallium diselenide (CIGS) is a promising material in thin film solar cell production. To make CIGS solar cells more competitive, both economically and environmentally, in comparison to other energy sources, methods for recycling are needed. In addition tomore » the generally high price of the material, significant amounts of the metals are lost in the manufacturing process. The feasibility of recycling selenium from CIGS through oxidation at elevated temperatures was therefore examined. During oxidation gaseous selenium dioxide was formed and could be separated from the other elements, which remained in solid state. Upon cooling, the selenium dioxide sublimes and can be collected as crystals. After oxidation for 1 h at 800 °C all of the selenium was separated from the CIGS material. Two different reduction methods for reduction of the selenium dioxide to selenium were tested. In the first reduction method an organic molecule was used as the reducing agent in a Riley reaction. In the second reduction method sulphur dioxide gas was used. Both methods resulted in high purity selenium. This proves that the studied selenium separation method could be the first step in a recycling process aimed at the complete separation and recovery of high purity elements from CIGS.« less

  4. Transmembrane topology of the acetylcholine receptor examined in reconstituted vesicles

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McCrea, P.D.

    1987-01-01

    Each of the five acetylcholine receptor (AChR) subunits, ..cap alpha../sub 2/..beta..-..gamma..delta, is believed to have the same number of transmembrane crossing and to share the same general folding pattern. AChR isolated from the electric organ of electric fish is predominantly dimeric. We have used this bridge as a marker for the C-terminus of the delta subunit, and presumably that of the other subunits in addition. The disulfide's accessibility to hydrophilic reductants, principally glutathione (GSH), was tested in a reconstituted vesicle system. The reduction of the delta-delta desulfide, as evidenced by the transition of AChrR dimers to monomers, was quantitatively monitoredmore » on velocity sedimentation sucrose gradients. Alternatively, the reduction of delta/sub 2/ to delta was followed by employing non-reducing SDS-PAGE. Reductants such as GSH were able to access the bridge in intact right-side-out vesicles. No acceleration of this process was evident when the vesicles were disrupted by freeze-thaw or by detergents. Control experiments which determined the rate of reduction of entrapped diphtheria toxin, or that of /sup 3/H-GSH efflux, demonstrated that intact reconstituted vesicles provide an adequate permeability barrier to GSH access of their intravesicular space.« less

  5. Social and monetary reward processing in autism spectrum disorders

    PubMed Central

    2012-01-01

    Background Social motivation theory suggests that deficits in social reward processing underlie social impairments in autism spectrum disorders (ASD). However, the extent to which abnormalities in reward processing generalize to other classes of stimuli remains unresolved. The aim of the current study was to examine if reward processing abnormalities in ASD are specific to social stimuli or can be generalized to other classes of reward. Additionally, we sought to examine the results in the light of behavioral impairments in ASD. Methods Participants performed adapted versions of the social and monetary incentive delay tasks. Data from 21 unmedicated right-handed male participants with ASD and 21 age- and IQ-matched controls were analyzed using a factorial design to examine the blood-oxygen-level-dependent (BOLD) response during the anticipation and receipt of both reward types. Results Behaviorally, the ASD group showed less of a reduction in reaction time (RT) for rewarded compared to unrewarded trials than the control group. In terms of the fMRI results, there were no significant group differences in reward circuitry during reward anticipation. During the receipt of rewards, there was a significant interaction between group and reward type in the left dorsal striatum (DS). The ASD group showed reduced activity in the DS compared to controls for social rewards but not monetary rewards and decreased activation for social rewards compared to monetary rewards. Controls showed no significant difference between the two reward types. Increased activation in the DS during social reward processing was associated with faster response times for rewarded trials, compared to unrewarded trials, in both groups. This is in line with behavioral results indicating that the ASD group showed less of a reduction in RT for rewarded compared to unrewarded trials. Additionally, de-activation to social rewards was associated with increased repetitive behavior in ASD. Conclusions In line with social motivation theory, the ASD group showed reduced activation, compared to controls, during the receipt of social rewards in the DS. Groups did not differ significantly during the processing of monetary rewards. BOLD activation in the DS, during social reward processing, was associated with behavioral impairments in ASD. PMID:23014171

  6. Social and monetary reward processing in autism spectrum disorders.

    PubMed

    Delmonte, Sonja; Balsters, Joshua H; McGrath, Jane; Fitzgerald, Jacqueline; Brennan, Sean; Fagan, Andrew J; Gallagher, Louise

    2012-09-26

    Social motivation theory suggests that deficits in social reward processing underlie social impairments in autism spectrum disorders (ASD). However, the extent to which abnormalities in reward processing generalize to other classes of stimuli remains unresolved. The aim of the current study was to examine if reward processing abnormalities in ASD are specific to social stimuli or can be generalized to other classes of reward. Additionally, we sought to examine the results in the light of behavioral impairments in ASD. Participants performed adapted versions of the social and monetary incentive delay tasks. Data from 21 unmedicated right-handed male participants with ASD and 21 age- and IQ-matched controls were analyzed using a factorial design to examine the blood-oxygen-level-dependent (BOLD) response during the anticipation and receipt of both reward types. Behaviorally, the ASD group showed less of a reduction in reaction time (RT) for rewarded compared to unrewarded trials than the control group. In terms of the fMRI results, there were no significant group differences in reward circuitry during reward anticipation. During the receipt of rewards, there was a significant interaction between group and reward type in the left dorsal striatum (DS). The ASD group showed reduced activity in the DS compared to controls for social rewards but not monetary rewards and decreased activation for social rewards compared to monetary rewards. Controls showed no significant difference between the two reward types. Increased activation in the DS during social reward processing was associated with faster response times for rewarded trials, compared to unrewarded trials, in both groups. This is in line with behavioral results indicating that the ASD group showed less of a reduction in RT for rewarded compared to unrewarded trials. Additionally, de-activation to social rewards was associated with increased repetitive behavior in ASD. In line with social motivation theory, the ASD group showed reduced activation, compared to controls, during the receipt of social rewards in the DS. Groups did not differ significantly during the processing of monetary rewards. BOLD activation in the DS, during social reward processing, was associated with behavioral impairments in ASD.

  7. Reduction of Iron-Oxide-Carbon Composites: Part III. Shrinkage of Composite Pellets during Reduction

    NASA Astrophysics Data System (ADS)

    Halder, S.; Fruehan, R. J.

    2008-12-01

    This article involves the evaluation of the volume change of iron-oxide-carbon composite pellets and its implications on reduction kinetics under conditions prevalent in a rotary hearth furnace (RHF) that were simulated in the laboratory. The pellets, in general, were found to shrink considerably during the reduction due to the loss of carbon and oxygen from the system, sintering of the iron-oxide, and formation of a molten slag phase at localized regions inside the pellets due to the presence of binder and coal/wood-charcoal ash at the reduction temperatures. One of the shortcomings of the RHF ironmaking process has been the inability to use multiple layers of composite pellets because of the impediment in heat transport to the lower layers of a multilayer bed. However, pellet shrinkage was found to have a strong effect on the reduction kinetics by virtue of enhancing the external heat transport to the lower layers. The volume change of the different kinds of composite pellets was studied as a function of reduction temperature and time. The estimation of the change in the amount of external heat transport with varying pellet sizes for a particular layer of a multilayer bed was obtained by conducting heat-transfer tests using inert low-carbon steel spheres. It was found that if the pellets of the top layer of the bed shrink by 30 pct, the external heat transfer to the second layer increases by nearly 6 times.

  8. An acoustic sensitivity study of general aviation propellers

    NASA Technical Reports Server (NTRS)

    Korkan, K. D.; Gregorek, G. M.; Keiter, I.

    1980-01-01

    This paper describes the results of a study in which a systematic approach has been taken in studying the effect of selected propeller parameters on the character and magnitude of propeller noise. Four general aviation aircraft were chosen, i.e., a Cessna 172, Cessna 210, Cessna 441, and a 19 passenger commuter concept, to provide a range in flight velocity, engine horsepower, and gross weight. The propeller parameters selected for examination consisted of number of blades, rpm reduction, thickness/chord reduction, activity factor reduction, proplets, airfoil improvement, sweep, position of maximum blade loading, and diameter reduction.

  9. Characterization of nickel laterite reduction from Pomalaa, Sulawesi Tenggara

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rhamdani, Ahmad Rizky; Petrus, Himawan T. B. M., E-mail: bayu.petrus@ugm.ac.id; Fahrurrozi, Moh.

    2015-12-29

    The effect of using different reductors in the reduction process of nickel laterite was investigated. In this work, the author conducted the reduction of nickel laterite ores by anthracite coal, lamtoro charcoal, and carbon raiser, in air and CO{sub 2} atmosphere, within the temperature ranged from 800°C and 1000°C. The results indicate that at higher temperatures, the reduction reactions proceed more complete. According to the X-ray powder diffraction (XRD) analysis, the type of carbon used greatly influence the rate of the reduction of nickel laterite. The order of reactivity is anthracite coal, lamtoro charcoal, and carbon raiser, respectively. The reductionmore » atmospheric condition also greatly influences the reduction process. The reduction process in CO{sub 2} atmospheric condition gives a lot of significant decrease in hematite and magnetite presence, means that the reduction reactions proceed more complete compared to the reduction process in the air atmospheric condition.« less

  10. AstroImageJ: Image Processing and Photometric Extraction for Ultra-precise Astronomical Light Curves

    NASA Astrophysics Data System (ADS)

    Collins, Karen A.; Kielkopf, John F.; Stassun, Keivan G.; Hessman, Frederic V.

    2017-02-01

    ImageJ is a graphical user interface (GUI) driven, public domain, Java-based, software package for general image processing traditionally used mainly in life sciences fields. The image processing capabilities of ImageJ are useful and extendable to other scientific fields. Here we present AstroImageJ (AIJ), which provides an astronomy specific image display environment and tools for astronomy specific image calibration and data reduction. Although AIJ maintains the general purpose image processing capabilities of ImageJ, AIJ is streamlined for time-series differential photometry, light curve detrending and fitting, and light curve plotting, especially for applications requiring ultra-precise light curves (e.g., exoplanet transits). AIJ reads and writes standard Flexible Image Transport System (FITS) files, as well as other common image formats, provides FITS header viewing and editing, and is World Coordinate System aware, including an automated interface to the astrometry.net web portal for plate solving images. AIJ provides research grade image calibration and analysis tools with a GUI driven approach, and easily installed cross-platform compatibility. It enables new users, even at the level of undergraduate student, high school student, or amateur astronomer, to quickly start processing, modeling, and plotting astronomical image data with one tightly integrated software package.

  11. Technical highlights in general aviation

    NASA Technical Reports Server (NTRS)

    Stickle, J. W.

    1977-01-01

    Improvements in performance, safety, efficiency, and emissions control in general aviation craft are reviewed. While change is slow, the U.S. industries still account for the bulk (90%) of the world's general aviation fleet. Advances in general aviation aerodynamics, structures and materials, acoustics, avionics, and propulsion are described. Supercritical airfoils, drag reduction design, stall/spin studies, crashworthiness and passenger safety, fiberglass materials, flight noise abatement, interior noise and vibration reduction, navigation systems, quieter and cleaner (reciprocating, turboprop, turbofan) engines, and possible benefits of the Global Position Satellite System to general aviation navigation are covered in the discussion. Some of the developments are illustrated.

  12. Mechanisms of Practice-Related Reductions of Dual-Task Interference with Simple Tasks: Data and Theory

    PubMed Central

    Strobach, Tilo; Torsten, Schubert

    2017-01-01

    In dual-task situations, interference between two simultaneous tasks impairs performance. With practice, however, this impairment can be reduced. To identify mechanisms leading to a practice-related improvement in sensorimotor dual tasks, the present review applied the following general hypothesis: Sources that impair dual-task performance at the beginning of practice are associated with mechanisms for the reduction of dual-task impairment at the end of practice. The following types of processes provide sources for the occurrence of this impairment: (a) capacity-limited processes within the component tasks, such as response-selection or motor response stages, and (b) cognitive control processes independent of these tasks and thus operating outside of component-task performance. Dual-task practice studies show that, under very specific conditions, capacity-limited processes within the component tasks are automatized with practice, reducing the interference between two simultaneous tasks. Further, there is evidence that response-selection stages are shortened with practice. Thus, capacity limitations at these stages are sources for dual-task costs at the beginning of practice and are overcome with practice. However, there is no evidence demonstrating the existence of practice-related mechanisms associated with capacity-limited motor-response stages. Further, during practice, there is an acquisition of executive control skills for an improved allocation of limited attention resources to two tasks as well as some evidence supporting the assumption of improved task coordination. These latter mechanisms are associated with sources of dual-task interference operating outside of component task performance at the beginning of practice and also contribute to the reduction of dual-task interference at its end. PMID:28439319

  13. Mathematical Analysis and Optimization of Infiltration Processes

    NASA Technical Reports Server (NTRS)

    Chang, H.-C.; Gottlieb, D.; Marion, M.; Sheldon, B. W.

    1997-01-01

    A variety of infiltration techniques can be used to fabricate solid materials, particularly composites. In general these processes can be described with at least one time dependent partial differential equation describing the evolution of the solid phase, coupled to one or more partial differential equations describing mass transport through a porous structure. This paper presents a detailed mathematical analysis of a relatively simple set of equations which is used to describe chemical vapor infiltration. The results demonstrate that the process is controlled by only two parameters, alpha and beta. The optimization problem associated with minimizing the infiltration time is also considered. Allowing alpha and beta to vary with time leads to significant reductions in the infiltration time, compared with the conventional case where alpha and beta are treated as constants.

  14. 18 CFR 2.500 - Penalty reduction/waiver policy for small entities.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Penalty reduction/waiver policy for small entities. 2.500 Section 2.500 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS...

  15. 18 CFR 2.500 - Penalty reduction/waiver policy for small entities.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Penalty reduction/waiver policy for small entities. 2.500 Section 2.500 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS...

  16. 18 CFR 2.500 - Penalty reduction/waiver policy for small entities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Penalty reduction/waiver policy for small entities. 2.500 Section 2.500 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS...

  17. 18 CFR 2.500 - Penalty reduction/waiver policy for small entities.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Penalty reduction/waiver policy for small entities. 2.500 Section 2.500 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS...

  18. Thermodynamic analysis of shark skin texture surfaces for microchannel flow

    NASA Astrophysics Data System (ADS)

    Yu, Hai-Yan; Zhang, Hao-Chun; Guo, Yang-Yu; Tan, He-Ping; Li, Yao; Xie, Gong-Nan

    2016-09-01

    The studies of shark skin textured surfaces in flow drag reduction provide inspiration to researchers overcoming technical challenges from actual production application. In this paper, three kinds of infinite parallel plate flow models with microstructure inspired by shark skin were established, namely blade model, wedge model and the smooth model, according to cross-sectional shape of microstructure. Simulation was carried out by using FLUENT, which simplified the computation process associated with direct numeric simulations. To get the best performance from simulation results, shear-stress transport k-omega turbulence model was chosen during the simulation. Since drag reduction mechanism is generally discussed from kinetics point of view, which cannot interpret the cause of these losses directly, a drag reduction rate was established based on the second law of thermodynamics. Considering abrasion and fabrication precision in practical applications, three kinds of abraded geometry models were constructed and tested, and the ideal microstructure was found to achieve best performance suited to manufacturing production on the basis of drag reduction rate. It was also believed that bionic shark skin surfaces with mechanical abrasion may draw more attention from industrial designers and gain wide applications with drag-reducing characteristics.

  19. GPU-computing in econophysics and statistical physics

    NASA Astrophysics Data System (ADS)

    Preis, T.

    2011-03-01

    A recent trend in computer science and related fields is general purpose computing on graphics processing units (GPUs), which can yield impressive performance. With multiple cores connected by high memory bandwidth, today's GPUs offer resources for non-graphics parallel processing. This article provides a brief introduction into the field of GPU computing and includes examples. In particular computationally expensive analyses employed in financial market context are coded on a graphics card architecture which leads to a significant reduction of computing time. In order to demonstrate the wide range of possible applications, a standard model in statistical physics - the Ising model - is ported to a graphics card architecture as well, resulting in large speedup values.

  20. Stochastic simulation and robust design optimization of integrated photonic filters

    NASA Astrophysics Data System (ADS)

    Weng, Tsui-Wei; Melati, Daniele; Melloni, Andrea; Daniel, Luca

    2017-01-01

    Manufacturing variations are becoming an unavoidable issue in modern fabrication processes; therefore, it is crucial to be able to include stochastic uncertainties in the design phase. In this paper, integrated photonic coupled ring resonator filters are considered as an example of significant interest. The sparsity structure in photonic circuits is exploited to construct a sparse combined generalized polynomial chaos model, which is then used to analyze related statistics and perform robust design optimization. Simulation results show that the optimized circuits are more robust to fabrication process variations and achieve a reduction of 11%-35% in the mean square errors of the 3 dB bandwidth compared to unoptimized nominal designs.

  1. Adaptive harvest management of North American waterfowl populations: a brief history and future prospects

    USGS Publications Warehouse

    Nichols, J.D.; Runge, M.C.; Johnson, F.A.; Williams, B.K.

    2007-01-01

    Since 1995, the US Fish and Wildlife Service has used an adaptive approach to the management of sport harvest of mid-continent Mallard ducks (Anas platyrhynchos) in North America. This approach differs from many current approaches to conservation and management in requiring close collaboration between managers and scientists. Key elements of this process are objectives, alternative management actions, models permitting prediction of system responses, and a monitoring program. The iterative process produces optimal management decisions and leads to reduction in uncertainty about response of populations to management. This general approach to management has a number of desirable features and is recommended for use in many other programs of management and conservation.

  2. A longitudinal high-risk study of adolescent anxiety, depression and parent-severity on the developmental course of risk-adjustment.

    PubMed

    Rawal, Adhip; Riglin, Lucy; Ng-Knight, Terry; Collishaw, Stephan; Thapar, Anita; Rice, Frances

    2014-11-01

    Adolescence is associated with developments in the reward system and increased rates of emotional disorders. Familial risk for depression may be associated with disruptions in the reward system. However, it is unclear how symptoms of depression and anxiety influence the development of reward-processing over adolescence and whether variation in the severity of parental depression is associated with hyposensitivity to reward in a high-risk sample. We focused on risk-adjustment (adjusting decisions about reward according to the probability of obtaining reward) as this was hypothesized to improve over adolescence. In a one-year longitudinal sample (N = 197) of adolescent offspring of depressed parents, we examined how symptoms of depression and anxiety (generalized anxiety and social anxiety) influenced the development of risk-adjustment. We also examined how parental depression severity influenced adolescent risk-adjustment. Risk-adjustment improved over the course of the study indicating improved adjustment of reward-seeking to shifting contingencies. Depressive symptoms were associated with decreases in risk-adjustment over time while social anxiety symptoms were associated with increases in risk-adjustment over time. Specifically, depression was associated with reductions in reward-seeking at favourable reward probabilities only, whereas social anxiety (but not generalized anxiety) led to reductions in reward-seeking at low reward probabilities only. Parent depression severity was associated with lowered risk-adjustment in offspring and also influenced the longitudinal relationship between risk-adjustment and offspring depression. Anxiety and depression distinctly alter the pattern of longitudinal change in reward-processing. Severity of parent depression was associated with alterations in adolescent offspring reward-processing in a high-risk sample. © 2014 The Authors. Journal of Child Psychology and Psychiatry published by John Wiley & Sons Ltd on behalf of Association for Child and Adolescent Mental Health.

  3. A comparison of the efficacy of carbamazepine and the novel anti-epileptic drug levetiracetam in the tetanus toxin model of focal complex partial epilepsy

    PubMed Central

    Doheny, H C; Whittington, M A; Jefferys, J G R; Patsalos, P N

    2002-01-01

    The tetanus toxin seizure model, which is associated with spontaneous and intermittent generalized and non-generalized seizures, is considered to reflect human complex partial epilepsy. The purpose of the present study was to investigate and compare the anticonvulsant effects of carbamazepine with that of levetiracetam, a new anti-epileptic drug in this model. One μl of tetanus toxin solution (containing 12 mLD50 μl−1 of tetanus toxin) was placed stereotactically into the rat left hippocampus resulting in generalized and non-generalized seizures. Carbamazepine (4 mg kg−1 h−1) and levetiracetam (8 and 16 mg kg−1 h−1) were administered during a 7 day period via an osmotic minipump which was placed in the peritoneal cavity. Carbamazepine (4 mg kg−1 h−1) exhibited no significant anticonvulsant effect, compared to control, when the entire 7 day study period was evaluated but the reduction in generalized seizures was greater (35.5%) than that for non-generalized seizures (12.6%). However, during the first 2 days of carbamazepine administration a significant reduction in both generalized seizure frequency (90%) and duration (25%) was observed. Non-generalized seizures were unaffected. This time-dependent anticonvulsant effect exactly paralleled the central (CSF) and peripheral (serum) kinetics of carbamazepine in that steady-state concentrations declined over time, with the highest concentrations achieved during the first 2 days. Also there was a significant 27.3% reduction in duration of generalized seizures during the 7 day study period (P=0.0001). Levetiracetam administration (8 and 16 mg kg−1 h−1) was associated with a dose-dependent reduction in the frequency of both generalized (39 v 57%) and non-generalized (36 v 41%) seizures. However, seizure suppression was more substantial for generalized seizures. Also a significant dose-dependent reduction in overall generalized seizure duration was observed. These data provide experimental evidence for the clinical efficacy of levetiracetam for the management of patients with complex partial seizures. Furthermore, levetiracetam probably does not act by preventing ictogenesis per se but acts to reduce seizure severity and seizure generalization. PMID:11906955

  4. Geochemical modeling of iron, sulfur, oxygen and carbon in a coastal plain aquifer

    USGS Publications Warehouse

    Brown, C.J.; Schoonen, M.A.A.; Candela, J.L.

    2000-01-01

    Fe(III) reduction in the Magothy aquifer of Long Island, NY, results in high dissolved-iron concentrations that degrade water quality. Geochemical modeling was used to constrain iron-related geochemical processes and redox zonation along a flow path. The observed increase in dissolved inorganic carbon is consistent with the oxidation of sedimentary organic matter coupled to the reduction of O2 and SO4/2- in the aerobic zone, and to the reduction of SO4/2- in the anaerobic zone; estimated rates of CO2 production through reduction of Fe(III) were relatively minor by comparison. The rates of CO2 production calculated from dissolved inorganic carbon mass transfer (2.55 x 10-4 to 48.6 x 10-4 mmol 1-1 yr-1) generally were comparable to the calculated rates of CO2 production by the combined reduction of O2, Fe(III) and SO4/2- (1.31 x 10-4 to 15 x 10-4 mmol 1-1 yr-1). The overall increase in SO4/2- concentrations along the flow path, together with the results of mass-balance calculations, and variations in ??34S values along the flow path indicate that SO4/2- loss through microbial reduction is exceeded by SO4/2- gain through diffusion from sediments and through the oxidation of FeS2. Geochemichal and microbial data on cores indicate that Fe(III) oxyhydroxide coatings on sediment grains in local, organic carbon- and SO4/2- -rich zones have localized SO4/2- -reducing zones in which the formation of iron disulfides been depleted by microbial reduction and resulted in decreases dissolved iron concentrations. These localized zones of SO4/2- reduction, which are important for assessing zones of low dissolved iron for water-supply development, could be overlooked by aquifer studies that rely only on groundwater data from well-water samples for geochemical modeling. (C) 2000 Elsevier Science B.V.Fe(III) reduction in the Magothy aquifer of Long Island, NY, results in high dissolved-iron concentrations that degrade water quality. Geochemical modeling was used to constrain iron-related geochemical processes and redox zonation along a flow path. The observed increase in dissolved inorganic carbon is consistent with the oxidation of sedimentary organic matter coupled to the reduction of O2 and SO42- in the aerobic zone, and to the reduction of SO42- in the anaerobic zone; estimated rates of CO2 production through reduction of Fe(III) were relatively minor by comparison. The rates of CO2 production calculated from dissolved inorganic carbon mass transfer (2.55??10-4 to 48.6??10-4mmol l-1yr-1) generally were comparable to the calculated rates of CO2 production by the combined reduction of O2, Fe(III) and SO42- (1.31??10-4 to 15??10-4mmol l-1yr-1). The overall increase in SO42- concentrations along the flow path, together with the results of mass-balance calculations, and variations in ??34S values along the flow path indicate that SO42- loss through microbial reduction is exceeded by SO42- gain through diffusion from sediments and through the oxidation of FeS2. Geochemical and microbial data on cores indicate that Fe(III) oxyhydroxide coatings on sediment grains in local, organic carbon- and SO42--rich zones have been depleted by microbial reduction and resulted in localized SO42--reducing zones in which the formation of iron disulfides decreases dissolved iron concentrations. These localized zones of SO42- reduction, which are important for assessing zones of low dissolved iron for water-supply development, could be overlooked by aquifer studies that rely only on groundwater data from well-water samples for geochemical modeling.

  5. Feature Reinforcement Learning: Part I. Unstructured MDPs

    NASA Astrophysics Data System (ADS)

    Hutter, Marcus

    2009-12-01

    General-purpose, intelligent, learning agents cycle through sequences of observations, actions, and rewards that are complex, uncertain, unknown, and non-Markovian. On the other hand, reinforcement learning is well-developed for small finite state Markov decision processes (MDPs). Up to now, extracting the right state representations out of bare observations, that is, reducing the general agent setup to the MDP framework, is an art that involves significant effort by designers. The primary goal of this work is to automate the reduction process and thereby significantly expand the scope of many existing reinforcement learning algorithms and the agents that employ them. Before we can think of mechanizing this search for suitable MDPs, we need a formal objective criterion. The main contribution of this article is to develop such a criterion. I also integrate the various parts into one learning algorithm. Extensions to more realistic dynamic Bayesian networks are developed in Part II (Hutter, 2009c). The role of POMDPs is also considered there.

  6. Extinction in neutrally stable stochastic Lotka-Volterra models

    NASA Astrophysics Data System (ADS)

    Dobrinevski, Alexander; Frey, Erwin

    2012-05-01

    Populations of competing biological species exhibit a fascinating interplay between the nonlinear dynamics of evolutionary selection forces and random fluctuations arising from the stochastic nature of the interactions. The processes leading to extinction of species, whose understanding is a key component in the study of evolution and biodiversity, are influenced by both of these factors. Here, we investigate a class of stochastic population dynamics models based on generalized Lotka-Volterra systems. In the case of neutral stability of the underlying deterministic model, the impact of intrinsic noise on the survival of species is dramatic: It destroys coexistence of interacting species on a time scale proportional to the population size. We introduce a new method based on stochastic averaging which allows one to understand this extinction process quantitatively by reduction to a lower-dimensional effective dynamics. This is performed analytically for two highly symmetrical models and can be generalized numerically to more complex situations. The extinction probability distributions and other quantities of interest we obtain show excellent agreement with simulations.

  7. Extinction in neutrally stable stochastic Lotka-Volterra models.

    PubMed

    Dobrinevski, Alexander; Frey, Erwin

    2012-05-01

    Populations of competing biological species exhibit a fascinating interplay between the nonlinear dynamics of evolutionary selection forces and random fluctuations arising from the stochastic nature of the interactions. The processes leading to extinction of species, whose understanding is a key component in the study of evolution and biodiversity, are influenced by both of these factors. Here, we investigate a class of stochastic population dynamics models based on generalized Lotka-Volterra systems. In the case of neutral stability of the underlying deterministic model, the impact of intrinsic noise on the survival of species is dramatic: It destroys coexistence of interacting species on a time scale proportional to the population size. We introduce a new method based on stochastic averaging which allows one to understand this extinction process quantitatively by reduction to a lower-dimensional effective dynamics. This is performed analytically for two highly symmetrical models and can be generalized numerically to more complex situations. The extinction probability distributions and other quantities of interest we obtain show excellent agreement with simulations.

  8. Sulfur and oxygen isotope fractionation during benzene, toluene, ethyl benzene, and xylene degradation by sulfate-reducing bacteria.

    PubMed

    Knöller, Kay; Vogt, Carsten; Richnow, Hans-Herrmann; Weise, Stephan M

    2006-06-15

    We examined the oxygen and sulfur isotope fractionation of sulfate during anaerobic degradation of toluene by sulfate-reducing bacteria in culture experiments with Desulfobacula toluolica as a type strain and with an enrichment culture Zz5-7 obtained from a benzene, toluene, ethylbenzene, and xylene (BTEX)-contaminated aquifer. Sulfur isotope fractionation can show considerable variation upon sulfate reduction and may react extremely sensitively to changes in environmental conditions. In contrast, oxygen isotope fractionation seems to be less sensitive to environmental changes. Our results clearly indicate that oxygen isotope fractionation is dominated by isotope exchange with ambient water. To verify our experimental results and to test the applicability of oxygen and sulfur isotope investigations under realistic field conditions, we evaluated isotope data from two BTEX-contaminated aquifers presented in the recent literature. On a field scale, bacterial sulfate reduction may be superimposed by processes such as dispersion, adsorption, reoxidation, or mixing. The dual isotope approach enables the identification of such sulfur transformation processes. This identification is vital for a general qualitative evaluation of the natural attenuation potential of the contaminated aquifer.

  9. Process Predictors of the Outcome of Group Drug Counseling

    PubMed Central

    Crits-Christoph, Paul; Johnson, Jennifer E.; Gibbons, Mary Beth Connolly; Gallop, Robert

    2012-01-01

    Objective This study examined the relation of process variables to the outcome of group drug counseling, a commonly used community treatment, for cocaine dependence. Method Videotaped group drug counseling sessions from 440 adult patients (23% female, 41% minority) were rated for member alliance, group cohesion, participation, self-disclosure, positive and non-positive feedback and advice, during the 6-month treatment of cocaine dependence. Average, session-level, and slopes of process scores were evaluated. Primary outcomes were monthly cocaine use (days using out of 30), next session cocaine use, and duration of sustained abstinence from cocaine. Secondary outcomes were endorsement of 12-step philosophy and beliefs about substance abuse. Results More positive alliances (with counselor) were associated with reductions in days using cocaine per month and next-session cocaine use, and increases in endorsement of 12-step philosophy. Patient self-disclosure about the past and degree of participation in the group were generally not predictive of group drug counseling outcomes. More advice from counselor and other group members were consistently associated with poorer outcomes in all categories. Individual differences in changes in process variables over time (linear slopes) were generally not predictive of treatment outcomes. Conclusions Some group behaviors widely believed to be associated with outcome, such as self-disclosure and participation, were not generally predictive of outcomes of group drug counseling, but alliance with the group counselor was positively associated, and advice giving negatively associated, with the outcome of treatments for cocaine dependence. PMID:23106760

  10. Process Setting through General Linear Model and Response Surface Method

    NASA Astrophysics Data System (ADS)

    Senjuntichai, Angsumalin

    2010-10-01

    The objective of this study is to improve the efficiency of the flow-wrap packaging process in soap industry through the reduction of defectives. At the 95% confidence level, with the regression analysis, the sealing temperature, temperatures of upper and lower crimper are found to be the significant factors for the flow-wrap process with respect to the number/percentage of defectives. Twenty seven experiments have been designed and performed according to three levels of each controllable factor. With the general linear model (GLM), the suggested values for the sealing temperature, temperatures of upper and lower crimpers are 185, 85 and 85° C, respectively while the response surface method (RSM) provides the optimal process conditions at 186, 89 and 88° C. Due to different assumptions between percentage of defective and all three temperature parameters, the suggested conditions from the two methods are then slightly different. Fortunately, the estimated percentage of defectives at 5.51% under GLM process condition and the predicted percentage of defectives at 4.62% under RSM process condition are not significant different. But at 95% confidence level, the percentage of defectives under RSM condition can be much lower approximately 2.16% than those under GLM condition in accordance with wider variation. Lastly, the percentages of defectives under the conditions suggested by GLM and RSM are reduced by 55.81% and 62.95%, respectively.

  11. Which types of hospital mergers save consumers money?

    PubMed

    Connor, R A; Feldman, R D; Dowd, B E; Radcliff, T A

    1997-01-01

    This study analyzes the changes in costs and prices from 1986 to 1994 for more than 3,500 U.S. short-term general hospitals, including 122 horizontal mergers. These mergers were generally financially beneficial to consumers, providing average price reductions of approximately 7 percent. Merger-related price reductions were considerably less in market areas with higher market concentration levels. Merger-related price reductions in areas with higher penetration by health maintenance organizations (HMOs) were approximately twice those in areas with lower HMO penetration. Merger-related price reductions were greater for low-occupancy hospitals, nonteaching hospitals, nonsystem hospitals, similar-size hospitals, and hospitals with greater premerger service duplication.

  12. Application of chitosan microparticles for reduction of vibrio species in seawater and live oysters (Crassostrea virginica).

    PubMed

    Fang, Lei; Wolmarans, Bernhard; Kang, Minyoung; Jeong, Kwang C; Wright, Anita C

    2015-01-01

    Human Vibrio infections associated with consumption of raw shellfish greatly impact the seafood industry. Vibrio cholerae-related disease is occasionally attributed to seafood, but V. vulnificus and V. parahaemolyticus are the primary targets of postharvest processing (PHP) efforts in the United States, as they pose the greatest threat to the industry. Most successful PHP treatments for Vibrio reduction also kill the molluscs and are not suitable for the lucrative half-shell market, while nonlethal practices are generally less effective. Therefore, novel intervention strategies for Vibrio reduction are needed for live oyster products. Chitosan is a bioactive derivative of chitin that is generally recognized as safe as a food additive by the FDA, and chitosan microparticles (CMs) were investigated in the present study as a potential PHP treatment for live oyster applications. Treatment of broth cultures with 0.5% (wt/vol) CMs resulted in growth cessation of V. cholerae, V. vulnificus, and V. parahaemolyticus, reducing culturable levels to nondetectable amounts after 3 h in three independent experiments. Furthermore, a similar treatment in artificial seawater at 4, 25, and 37°C reduced V. vulnificus levels by ca. 7 log CFU/ml after 24 h of exposure, but 48 h of exposure and elevated temperature were required to achieve similar results for V. parahaemolyticus and V. cholerae. Live oysters that either were artificially inoculated or contained natural populations of V. vulnificus and V. parahaemolyticus showed significant and consistent reductions following CM treatment (5%) compared to the amounts in the untreated controls. Thus, the results strongly support the promising potential for the application of CMs as a PHP treatment to reduce Vibrio spp. in intact live oysters. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  13. Evaluating a policing strategy intended to disrupt an illicit street-level drug market.

    PubMed

    Corsaro, Nicholas; Brunson, Rod K; McGarrell, Edmund F

    2010-12-01

    The authors examined a strategic policing initiative that was implemented in a high crime Nashville, Tennessee neighborhood by utilizing a mixed-methodological evaluation approach in order to provide (a) a descriptive process assessment of program fidelity; (b) an interrupted time-series analysis relying upon generalized linear models; (c) in-depth resident interviews. Results revealed that the initiative corresponded with a statistically significant reduction in drug and narcotics incidents as well as perceived changes in neighborhood disorder within the target community. There was less-clear evidence, however, of a significant impact on other outcomes examined. The implications that an intensive crime prevention strategy corresponded with a reduction in specific forms of neighborhood crime illustrates the complex considerations that law enforcement officials face when deciding to implement this type of crime prevention initiative.

  14. Effect of closed-loop order processing on the time to initial antimicrobial therapy.

    PubMed

    Panosh, Nicole; Rew, Richardd; Sharpe, Michelle

    2012-08-15

    The results of a study comparing the average time to initiation of i.v. antimicrobial therapy with closed-versus open-loop order entry and processing are reported. A retrospective cohort study was performed to compare order-to-administration times for initial doses of i.v. antimicrobials before and after a closed-loop order-processing system including computerized prescriber order entry (CPOE) was implemented at a large medical center. A total of 741 i.v. antimicrobial administrations to adult patients during designated five-month preimplementation and postimplementation study periods were assessed. Drug-use reports generated by the pharmacy database were used to identify order-entry times, and medication administration records were reviewed to determine times of i.v. antimicrobial administration. The mean ± S.D. order-to-administration times before and after the implementation of the CPOE system and closed-loop order processing were 3.18 ± 2.60 and 2.00 ± 1.89 hours, respectively, a reduction of 1.18 hours (p < 0.0001). Closed-loop order processing was associated with significant reductions in the average time to initiation of i.v. therapy in all patient care areas evaluated (cardiology, general medicine, and oncology). The study results suggest that CPOE-based closed-loop order processing can play an important role in achieving compliance with current practice guidelines calling for increased efforts to ensure the prompt initiation of i.v. antimicrobials for severe infections (e.g., sepsis, meningitis). Implementation of a closed-loop order-processing system resulted in a significant decrease in order-to-administration times for i.v. antimicrobial therapy.

  15. Synthesis of Supported Pd 0 Nanoparticles from a Single-Site Pd 2+ Surface Complex by Alkene Reduction

    DOE PAGES

    Mouat, Aidan R.; Whitford, Cassandra L.; Chen, Bor-Rong; ...

    2018-02-02

    Here, a surface metal–organic complex, (-AlO x)Pd(acac) (acac = acetylacetonate), is prepared by chemically grafting the precursor Pd(acac) 2 onto γ-Al 2O 3 in toluene at 25 °C. The resulting surface complex is characterized by inductively coupled plasma atomic emission spectroscopy (ICP-AES), X-ray photoelectron spectroscopy (XPS), X-ray absorption spectroscopy (XAS), and dynamic nuclear polarization surface-enhanced solid-state nuclear magnetic resonance spectroscopy (DNP SENS). This surface complex is a precursor in the direct synthesis of size-controlled Pd nanoparticles under mild reductive conditions and in the absence of additional stabilizers or pretreatments. Indeed, upon exposure to gaseous ethylene or liquid 1-octene at 25more » °C, the Pd 2+ species is reduced to form Pd 0 nanoparticles with a mean diameter of 4.3 ± 0.6 nm, as determined by scanning transmission electron microscopy (STEM). These nanoparticles are catalytically relevant using the aerobic 1-phenylethanol oxidation as a probe reaction, with rates comparable to a conventional Pd/Al 2O 3 catalyst but without an induction period. Diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) and temperature-programmed reaction mass spectrometry (TPR-MS) reveal that the surface complex reduction with ethylene coproduces H 2, acetylene, and 1,3-butadiene. This process reasonably proceeds via an olefin activation/coordination/insertion pathway, followed by β-hydride elimination to generate free Pd 0. Lastly, the well-defined nature of the single-site supported Pd 2+ precursor provides direct mechanistic insights into this unusual and likely general reductive process.« less

  16. Synthesis of Supported Pd 0 Nanoparticles from a Single-Site Pd 2+ Surface Complex by Alkene Reduction

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mouat, Aidan R.; Whitford, Cassandra L.; Chen, Bor-Rong

    Here, a surface metal–organic complex, (-AlO x)Pd(acac) (acac = acetylacetonate), is prepared by chemically grafting the precursor Pd(acac) 2 onto γ-Al 2O 3 in toluene at 25 °C. The resulting surface complex is characterized by inductively coupled plasma atomic emission spectroscopy (ICP-AES), X-ray photoelectron spectroscopy (XPS), X-ray absorption spectroscopy (XAS), and dynamic nuclear polarization surface-enhanced solid-state nuclear magnetic resonance spectroscopy (DNP SENS). This surface complex is a precursor in the direct synthesis of size-controlled Pd nanoparticles under mild reductive conditions and in the absence of additional stabilizers or pretreatments. Indeed, upon exposure to gaseous ethylene or liquid 1-octene at 25more » °C, the Pd 2+ species is reduced to form Pd 0 nanoparticles with a mean diameter of 4.3 ± 0.6 nm, as determined by scanning transmission electron microscopy (STEM). These nanoparticles are catalytically relevant using the aerobic 1-phenylethanol oxidation as a probe reaction, with rates comparable to a conventional Pd/Al 2O 3 catalyst but without an induction period. Diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) and temperature-programmed reaction mass spectrometry (TPR-MS) reveal that the surface complex reduction with ethylene coproduces H 2, acetylene, and 1,3-butadiene. This process reasonably proceeds via an olefin activation/coordination/insertion pathway, followed by β-hydride elimination to generate free Pd 0. Lastly, the well-defined nature of the single-site supported Pd 2+ precursor provides direct mechanistic insights into this unusual and likely general reductive process.« less

  17. 8 CFR 273.5 - General criteria used for reduction, refund, or waiver of fines.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false General criteria used for reduction, refund, or waiver of fines. 273.5 Section 273.5 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY..., liquidated damages, and user fee payment records; and, (3) The existence of any extenuating circumstances. ...

  18. 8 CFR 273.5 - General criteria used for reduction, refund, or waiver of fines.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false General criteria used for reduction, refund, or waiver of fines. 273.5 Section 273.5 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY..., liquidated damages, and user fee payment records; and, (3) The existence of any extenuating circumstances. ...

  19. 8 CFR 273.5 - General criteria used for reduction, refund, or waiver of fines.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false General criteria used for reduction, refund, or waiver of fines. 273.5 Section 273.5 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY..., liquidated damages, and user fee payment records; and, (3) The existence of any extenuating circumstances. ...

  20. 8 CFR 273.5 - General criteria used for reduction, refund, or waiver of fines.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false General criteria used for reduction, refund, or waiver of fines. 273.5 Section 273.5 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY..., liquidated damages, and user fee payment records; and, (3) The existence of any extenuating circumstances. ...

  1. 8 CFR 273.5 - General criteria used for reduction, refund, or waiver of fines.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false General criteria used for reduction, refund, or waiver of fines. 273.5 Section 273.5 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY..., liquidated damages, and user fee payment records; and, (3) The existence of any extenuating circumstances. ...

  2. ORAC-DR -- Programmer's Guide

    NASA Astrophysics Data System (ADS)

    Jenness, Tim; Economou, Frossie; Cavanagh, Brad

    ORAC-DR is a general purpose automatic data reduction pipeline environment. This document describes how to modify data reduction recipes and how to add new instruments. For a general overview of ORAC-DR see SUN/230. For specific information on how to reduce the data for a particular instrument, please consult the appropriate ORAC-DR instrument guide.

  3. Development of mechanical properties in a CaO added AZ31 magnesium alloy processed by equal-channel angular pressing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bae, Seong-Hwan; Metal Forming Technology R&D Group, Korea Institute of Industrial Technology, Incheon 406-840; Jung, Ki Ho

    Processing through the application of equal-channel angular pressing (ECAP) is recognized as one of the attractive severe plastic deformation techniques where the processed bulk metals generally achieve ultrafine-grained microstructure leading to improved physical characteristics and mechanical properties. Magnesium has received much attention to date for its lightweight, high strength and excellent elasticity. Mg alloys with addition of CaO is reported to provide the successful casting procedure without usage of greenhouse gas, SF{sub 6}, whereas it is generally used for preventing the oxidation of Mg during casting. In the present investigation, a CaO added AZ31 (AZ31-CaO) magnesium alloy was processed bymore » ECAP at elevated temepratures with a few steps of reduction which result in significant grain refinement to ~ 1.5 μm after 6 passes. Compression testing at room temperature demonstrated the AZ31-CaO alloy after ECAP showed enhanced yield strength more than the as-processed commercial AZ31 alloy while both alloys maintained ductility in spite of significant reduction in grain size. The improved strength in the AZ31-CaO alloy was attributed to the formation of fine Al{sub 2}Ca precipitates which experience breaking-up through ECAP and accelerate the microstructural refinement. Moreover, the preservation of ductility was attributed to the enhancement of strain hardening capability in the AZ31 alloy at room temperature. This study discusses the feasibility of using ECAP to improve both strength and ductility on magnesium alloys by applying the diagram describing the paradox of strength and ductility. - Highlights: • AZ31 and AZ31-CaO magnesium alloys were processed by ECAP up to 6 passes. • AZ31-CaO alloy after ECAP showed improved yield strength without losing ductility. • CaO in AZ31 forms fine Al{sub 2}Ca accelerating microstructural refinement during ECAP. • Feasibility of using ECAP was shown to improve both strength and ductility in Mg.« less

  4. The mechanical properties and microstructures of vanadium bearing high strength dual phase steels processed with continuous galvanizing line simulations

    NASA Astrophysics Data System (ADS)

    Gong, Yu

    For galvanized or galvannealed steels to be commercially successful, they must exhibit several attributes: (i) easy and inexpensive processing in the hot mill, cold mill and on the coating line, (ii) high strength with good formability and spot weldability, and (iii) good corrosion resistance. At the beginning of this thesis, compositions with a common base but containing various additions of V or Nb with or without high N were designed and subjected to Gleeble simulations of different galvanizing(GI), galvannealing(GA) and supercooling processing. The results revealed the phase balance was strongly influenced by the different microalloying additions, while the strengths of each phase were somewhat less affected. Our research revealed that the amount of austenite formed during intercritical annealing can be strongly influenced by the annealing temperature and the pre-annealing conditions of the hot band (coiling temperature) and cold band (% cold reduction). In the late part of this thesis, the base composition was a low carbon steel which would exhibit good spot weldability. To this steel were added two levels of Cr and Mo for strengthening the ferrite and increasing the hardenability of intercritically formed austenite. Also, these steels were produced with and without the addition of vanadium in an effort to further increase the strength. Since earlier studies revealed a relationship between the nature of the starting cold rolled microstructure and the response to CGL processing, the variables of hot band coiling temperature and level of cold reduction prior to annealing were also studied. Finally, in an effort to increase strength and ductility of both the final sheet (general formability) and the sheared edges of cold punched holes (local formability), a new thermal path was developed that replaced the conventional GI ferrite-martensite microstructure with a new ferrite-martensite-tempered martensite and retained austenite microstructure. The new microstructure exhibited a somewhat lower strength but much high general and local formabilities. In this thesis, both the physical and mechanical metallurgy of these steels and processes will be discussed. This research has shown that simple compositions and processes can result in DP steels with so-called Generation III properties.

  5. Plenary Lecture 3: Food and the planet: nutritional dilemmas of greenhouse gas emission reductions through reduced intakes of meat and dairy foods.

    PubMed

    Millward, D Joe; Garnett, Tara

    2010-02-01

    Legally-binding legislation is now in place to ensure major reductions in greenhouse gas emissions in the UK. Reductions in intakes of meat and dairy products, which account for approximately 40% of food-related emissions, are an inevitable policy option. The present paper assesses, as far as is possible, the risk to nutritional status of such a policy in the context of the part played by these foods in overall health and well-being and their contribution to nutritional status for the major nutrients that they supply. Although meat may contribute to saturated fat intakes and a higher BMI, moderate meat consumption within generally-healthy population groups has no measurable influence on morbidity or mortality. However, high consumption of red and processed meat has been associated with increased risk of colo-rectal cancer and recent advice is to reduce intakes to a maximum of 70 g/d. Such reductions in meat and haem-Fe intake are unlikely to influence Fe status in functional terms. However, overall protein intakes would probably fall, with the potential for intakes to be less than current requirements for the elderly. Whether it is detrimental to health is uncertain and controversial. Zn intakes are also likely to fall, raising questions about child growth that are currently unanswerable. Milk and dairy products, currently specifically recommended for young children and pregnant women, provide 30-40% of dietary Ca, iodine, vitamin B12 and riboflavin. Population groups with low milk intakes generally show low intakes and poor status for each of these nutrients. Taken together it would appear that the reductions in meat and dairy foods, which are necessary to limit environmental damage, do pose serious nutritional challenges for some key nutrients. These challenges can be met, however, by improved public health advice on alternative dietary sources and by increasing food fortification.

  6. The Soil Sink for Nitrous Oxide: Trivial Amount but Challenging Question

    NASA Astrophysics Data System (ADS)

    Davidson, E. A.; Savage, K. E.; Sihi, D.

    2015-12-01

    Net uptake of atmospheric nitrous oxide (N2O) has been observed sporadically for many years. Such observations have often been discounted as measurement error or noise, but they were reported frequently enough to gain some acceptance as valid. The advent of fast response field instruments with good sensitivity and precision has permitted confirmation that some soils can be small sinks of N2O. With regards to "closing the global N2O budget" the soil sink is trivial, because it is smaller than the error terms of most other budget components. Although not important from a global budget perspective, the existence of a soil sink for atmospheric N2O presents a fascinating challenge for understanding the physical, chemical, and biological processes that explain the sink. Reduction of N2O by classical biological denitrification requires reducing conditions generally found in wet soil, and yet we have measured the N2O sink in well drained soils, where we also simultaneously measure a sink for atmospheric methane (CH4). Co-occurrence of N2O reduction and CH4 oxidation would require a broad range of microsite conditions within the soil, spanning high and low oxygen concentrations. Abiotic sinks for N2O or other biological processes that consume N2O could exist, but have not yet been identified. We are attempting to simulate processes of diffusion of N2O, CH4, and O2 from the atmosphere and within a soil profile to determine if classical biological N2O reduction and CH4 oxidation at rates consistent with measured fluxes are plausible.

  7. [Treatment of acrylate wastewater by electrocatalytic reduction process].

    PubMed

    Yu, Li-Na; Song, Yu-Dong; Zhou, Yue-Xi; Zhu, Shu-Quan; Zheng, Sheng-Zhi; Ll, Si-Min

    2011-10-01

    High-concentration acrylate wastewater was treated by an electrocatalytic reduction process. The effects of the cation exchange membrane (CEM) and cathode materials on acrylate reduction were investigated. It indicated that the acrylate could be reduced to propionate acid efficiently by the electrocatalytic reduction process. The addition of CEM to separator with the cathode and anode could significantly improve current efficiency. The cathode materials had significant effect on the reduction of acrylate. The current efficiency by Pd/Nickel foam, was greater than 90%, while those by nickel foam, the carbon fibers and the stainless steel decreased successively. Toxicity of the wastewater decreased considerably and methane production rate in the biochemical methane potential (BMP) test increased greatly after the electrocatalytic reduction process.

  8. Experimental study on combined cold forging process of backward cup extrusion and piercing

    NASA Astrophysics Data System (ADS)

    Henry, Robinson; Liewald, Mathias

    2018-05-01

    A reduction in material usage of cold forged components while maintaining the functional requirements can be achieved using hollow or tubular preforms. These preforms are used to meet lightweight requirements and to decrease production costs of cold formed components. To increase production efficiency in common multi-stage cold forming processes, manufacturing of hollow preforms by combining the processes backward cup extrusion and piercing was established and will be discussed in this paper. Corresponding investigations and experimental studies are reported in this article. The objectives of the experimental investigations have been the detection of significant process parameters, determination of process limits for the combined processes and validation of the numerical investigations. In addition, the general influence concerning surface quality and diameter tolerance of hollow performs are discussed in this paper. The final goal is to summarize a guideline for industrial application, moreover, to transfer the knowledge to industry, as regards what are required part geometries to reduce the number of forming stages as well as tool cost.

  9. Effect of paste processing on residue levels of imidacloprid, pyraclostrobin, azoxystrobin and fipronil in winter jujube.

    PubMed

    Peng, Wei; Zhao, Liuwei; Liu, Fengmao; Xue, Jiaying; Li, Huichen; Shi, Kaiwei

    2014-01-01

    The changes of imidacloprid, pyraclostrobin, azoxystrobin and fipronil residues were studied to investigate the carryover of pesticide residues in winter jujube during paste processing. A multi-residue analytical method for winter jujube was developed based on the QuEChERS approach. The recoveries for the pesticides were between 87.5% and 116.2%. LODs ranged from 0.002 to 0.1 mg kg(-1). The processing factor (Pf) is defined as the ratio of pesticide residue concentration in the paste to that in winter jujube. Pf was higher than 1 for the removal of extra water, and other steps were generally less than 1, indicating that the whole process resulted in lower pesticide residue levels in paste. Peeling would be the critical step for pesticide removal. Processing factors varied among different pesticides studied. The results are useful to address optimisation of the processing techniques in a manner that leads to considerable pesticide residue reduction.

  10. 48 CFR 970.5215-4 - Cost reduction.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Cost reduction. 970.5215-4... and Operating Contracts 970.5215-4 Cost reduction. As prescribed in 970.1504-5(c), insert the following clause: Cost Reduction (AUG 2009) (a) General. It is the Department of Energy's (DOE's) intent to...

  11. 36 CFR 218.2 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... ADMINISTRATIVE REVIEW PROCESSES Predecisional Administrative Review Process for Hazardous Fuel Reduction Projects... reduction project: A hazardous fuel reduction project authorized by the Healthy Forests Restoration Act of... reduction project pursuant to the HFRA. Decision notice (DN): A concise written record of a responsible...

  12. Building America Case Study: Project Overcoat: Airtightness Strategies and Impacts for 1-1/2 Story Homes, Minneapolis, Minnesota (Fact Sheet)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    In this second study on solutions to ice dams in 1-1/2 story homes, five test homes located in both cold and very cold climates were analyzed for air leakage reduction rates following modifications by independent contractors on owner-occupied homes. The reason for choosing this house type was they are very common in our area and very difficult to air seal and insulate effectively. Two projects followed a roof-only Exterior Thermal Moisture Management System (ETMMS) process. One project used an interior-only approach to roof air sealing and insulation. The remaining two projects used a deep energy retrofit approach for whole housemore » (foundation wall, above grade wall, roof) air leakage and heat loss reduction. All were asked to provide information regarding project goals, process, and pre and post-blower door test results. Additional air leakage reduction data was provided by several NorthernSTAR Building America industry partners for interior-applied, roof-only modifications on 1-1/2 story homes. The data represents homes in the general market as well as homes that were part of the state of Minnesota weatherization program. A goal was to compare exterior air sealing methods with interior approaches. This pool of data enabled us to compare air tightness data from over 220 homes using similar air seal methods.« less

  13. Airtightness Results of Roof-Only Air Sealing Strategies on 1-1/2 Story Homes in Cold Climates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ojczyk, C.; Murry, T.; Mosiman, G.

    In this second study on solutions to ice dams in 1-1/2 story homes, five test homes located in both cold and very cold climates were analyzed for air leakage reduction rates following modifications by independent contractors on owner-occupied homes. The reason for choosing this house type was they are very common in our area and very difficult to air seal and insulate effectively. Two projects followed a roof-only Exterior Thermal Moisture Management System (ETMMS) process. One project used an interior-only approach to roof air sealing and insulation. The remaining two projects used a deep energy retrofit approach for whole housemore » (foundation wall, above grade wall, roof) air leakage and heat loss reduction. All were asked to provide information regarding project goals, process, and pre and post-blower door test results. Additional air leakage reduction data was provided by several NorthernSTAR Building America industry partners for interior-applied, roof-only modifications on 1-1/2 story homes. The data represents homes in the general market as well as homes that were part of the state of Minnesota weatherization program. A goal was to compare exterior air sealing methods with interior approaches. This pool of data enabled us to compare air tightness data from over 220 homes using similar air seal methods.« less

  14. Airtightness Results of Roof-Only Air Sealing Strategies on 1 ½-Story Homes in Cold Climates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ojczyk, C.; Murry, T.; Mosiman, G.

    In this second study on solutions to ice dams in 1-1/2 story homes, the NorthernSTAR Building America Partnership team analyzed five test homes located in both cold and very cold climates for air leakage reduction rates following modifications by independent contractors on owner-occupied homes. These homes were chosen for testing as they are common in Minnesota and very difficult to air seal and insulate effectively. Two projects followed a roof-only Exterior Thermal Moisture Management System (ETMMS) process. One project used an interior-only approach to roof air sealing and insulation. The remaining two projects used a deep energy retrofit approach formore » whole house (foundation wall, above grade wall, roof) air leakage and heat loss reduction. All were asked to provide information regarding project goals, process, and pre and post-blower door test results. Additional air leakage reduction data was provided by several NorthernSTAR industry partners for interior-applied, roof-only modifications on 1-1/2 story homes. The data represents homes in the general market as well as homes that were part of the state of Minnesota weatherization program. A goal was to compare exterior air sealing methods with interior approaches. This pool of data enabled the team to compare air tightness data from over 220 homes using similar air seal methods.« less

  15. Selective Engagement of Cognitive Resources: Motivational Influences on Older Adults’ Cognitive Functioning

    PubMed Central

    Hess, Thomas M.

    2018-01-01

    In this article, I present a framework for understanding the impact of aging-related declines in cognitive resources on functioning. I make the assumption that aging is associated with an increase in the costs of cognitive engagement, as reflected in both the effort required to achieve a specific level of task performance and the associated depletion or fatigue effects. I further argue that these costs result in older adults being increasingly selective in the engagement of cognitive resources in response to these declines. This selectivity is reflected in (a) a reduction in the intrinsic motivation to engage in cognitively demanding activities, which, in part, accounts for general reductions in engagement in such activities, and (b) greater sensitivity to the self-related implications of a given task. Both processes are adaptive if viewed in terms of resource conservation, but the former may also be maladaptive to the extent that it results in older adults restricting participation in cognitively demanding activities that could ultimately benefit cognitive health. I review supportive research and make the general case for the importance of considering motivational factors in understanding aging effects on cognitive functioning. PMID:26173272

  16. Staggered work shifts: a way to downsize and restructure an emergency department workforce yet maintain current operational performance.

    PubMed

    Sinreich, David; Jabali, Ola

    2007-09-01

    Starting from the last decade of the twentieth century, most hospital Emergency Department (ED) budgets did not keep up with the demand for ED services made by growing populations and aging societies. Since labor consumes over 50% of the total monies invested in EDs and other healthcare systems, any downsizing, streamlining and reorganization plan needs to first address staffing issues such as determining the correct size of the workforce and its work shift scheduling. In this context, it is very important to remember that downsizing certainly does not mean a general cut-across-the-board. This study shows that a selective downsizing process in which each resource is treated separately (increasing the work capacity of some resources is also possible), based on its unique contribution to the overall ED operational performance, can approximately maintain current ED operational measures in terms patient length of stay (LOS) despite an overall reduction in staff hours. A linear optimization model (S-model) and a heuristic iterative simulation based algorithm (SWSSA) are used in this study for scheduling the resources' work shifts, one resource at a time. The algorithm was tested using data that was gathered from five general hospital EDs. By leveling the workload of the different resources in the ED, SWSSA was able to achieve LOS values within -19 to 4% of the original values despite a reduction of 8-17.5% in physicians' work hours and a reduction of 13-47% in the nurses' work hours.

  17. Monoclonal antibody disulfide reduction during manufacturing

    PubMed Central

    Hutterer, Katariina M.; Hong, Robert W.; Lull, Jonathon; Zhao, Xiaoyang; Wang, Tian; Pei, Rex; Le, M. Eleanor; Borisov, Oleg; Piper, Rob; Liu, Yaoqing Diana; Petty, Krista; Apostol, Izydor; Flynn, Gregory C.

    2013-01-01

    Manufacturing-induced disulfide reduction has recently been reported for monoclonal human immunoglobulin gamma (IgG) antibodies, a widely used modality in the biopharmaceutical industry. This effect has been tied to components of the intracellular thioredoxin reduction system that are released upon cell breakage. Here, we describe the effect of process parameters and intrinsic molecule properties on the extent of reduction. Material taken from cell cultures at the end of production displayed large variations in the extent of antibody reduction between different products, including no reduction, when subjected to the same reduction-promoting harvest conditions. Additionally, in a reconstituted model in which process variables could be isolated from product properties, we found that antibody reduction was dependent on the cell line (clone) and cell culture process. A bench-scale model using a thioredoxin/thioredoxin reductase regeneration system revealed that reduction susceptibility depended on not only antibody class but also light chain type; the model further demonstrates that the trend in reducibility was identical to DTT reduction sensitivity following the order IgG1λ > IgG1κ > IgG2λ > IgG2κ. Thus, both product attributes and process parameters contribute to the extent of antibody reduction during production. PMID:23751615

  18. Reduction and reconstruction of the dynamics of nonholonomic systems

    NASA Astrophysics Data System (ADS)

    Cortés, Jorge; de León, Manuel

    1999-12-01

    The reduction and reconstruction of the dynamics of nonholonomic mechanical systems with symmetry are investigated. We have considered a more general framework of constrained Hamiltonian systems since they appear in the reduction procedure. A reduction scheme in terms of the nonholonomic momentum mapping is developed. The reduction of the nonholonomic brackets is also discussed. The theory is illustrated with several examples.

  19. Life cycle assessment of oriented strand boards (OSB): from process innovation to ecodesign.

    PubMed

    Benetto, Enrico; Becker, Marko; Welfring, Joëlle

    2009-08-01

    Oriented strand boards (OSBs) are wood panels that are used worldwide mainly in the packaging and the building sectors. Their market share is rapidly increasing thanks to their outstanding mechanical properties and to a renewed interest for wood based products. The OSB production process generates, nonetheless, emissions of volatile organic compounds (VOCs) during the air-drying of wood strands. This known problem in the literature leads to an odorous nuisance in the surrounding area of the production site. In order to address this problem, a novel application to wood drying of an innovative vapor drying technology is successfully operated at the production site of Kronospan Luxembourg S.A. In addition to the reduced odorous nuisance, a significant environmental added value is expected because of the other modifications induced by the vapor-drying technique on the OSB production process viz. the reduced energy and raw materials demands and the change of adhesive mixture, with the addition of phenol resin. The potential impact of this technology on the OSB market is therefore very significant. This study was aimed at assessing the environmental added value provided by the vapor-drying technique through a life cycle assessment (LCA) according to ISO 14040-44 standards. The objective was to compare the environmental performances of the former and the current OSB production processes. Considering only the pollutant emissions from the OSB production process, the reduction of climate change impact and human health damage is significant respectively, 15-20% and 50-75%. When the lifecycle processes related to the OSB production are included, the reduction of damages does not exceed 3-7%. Following an uncertainty analysis,this reduction was nevertheless proven to be statistically significant. However, it is observed that the reduction of environmental impacts and damages allowed by the vapor-drying technology is counterbalanced by the change of adhesive mixture. Indeed the new adhesive mixture generates higher environmental damages than the former mixture because of the higher energy and raw material demand from phenol resin production. These results show the need to move from an approach focused on a single process innovation (the vapor-drying technique) to a more general and systemic approach combining process and product ecodesign. Such approaches are needed in order to effectively improve the overall environmental performance of a production system, without transfer of pollution along the lifecycle or offsets of pollution credits. LCA is definitively one of the most pertinent tools to identify improvement opportunities in the comparison of alternative designs from an environmental perspective.

  20. Tritordeum: a novel cereal for food processing with good acceptability and significant reduction in gluten immunogenic peptides in comparison with wheat.

    PubMed

    Vaquero, Luis; Comino, Isabel; Vivas, Santiago; Rodríguez-Martín, Laura; Giménez, María J; Pastor, Jorge; Sousa, Carolina; Barro, Francisco

    2018-04-01

    Tritordeum is a novel cereal obtained from the hybridization between durum wheat and a wild barley. This study evaluates acceptance, digestibility and immunotoxic properties of tritordeum, a novel cereal for food processing. Nineteen healthy volunteers participated in a study with different diets to compare tritordeum bread with wheat and gluten-free breads. Tritordeum breads had a similar acceptance to the wheat bread usually consumed, and the acceptance was significantly higher than the gluten-free bread and standardized wheat bread supplied in the study. There was no evidence for gastrointestinal symptoms among volunteers during the study. The reductions in the numbers of immunogenic epitopes in tritordeum in comparison with wheat were 78% for α-gliadins, 57% for γ-gliadins and 93% for ω-gliadins. The analysis of gluten immunogenic peptides (GIP) in stool samples showed a significantly lower excretion in the tritordeum ingestion phase than in the wheat ingestion phase. These results suggest that tritordeum may be an option of interest for general food processing, and especially for those who want to reduce their intake of gluten. However, it is not suitable for celiac disease sufferers as it contains gluten. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  1. [Quality management (TQM) in public health-care (PHC): principles for cost-performance calculations and cost reductions with better quality].

    PubMed

    Bergholz, W

    2008-11-01

    In many high-tech industries, quality management (QM) has enabled improvements of quality by a factor of 100 or more, in combination with significant cost reductions. Compared to this, the application of QM methods in health care is in its initial stages. It is anticipated that stringent process management, embedded in an effective QM system will lead to significant improvements in health care in general and in the German public health service in particular. Process management is an ideal platform for controlling in the health care sector, and it will significantly improve the leverage of controlling to bring down costs. Best practice sharing in industry has led to quantum leap improvements. Process management will enable best practice sharing also in the public health service, in spite of the highly diverse portfolio of services that the public health service offers in different German regions. Finally, it is emphasised that "technical" QM, e.g., on the basis of the ISO 9001 standard is not sufficient to reach excellence. It is necessary to integrate soft factors, such as patient or employee satisfaction, and leadership quality into the system. The EFQM model for excellence can serve as proven tool to reach this goal.

  2. Development of an Uncertainty Model for the National Transonic Facility

    NASA Technical Reports Server (NTRS)

    Walter, Joel A.; Lawrence, William R.; Elder, David W.; Treece, Michael D.

    2010-01-01

    This paper introduces an uncertainty model being developed for the National Transonic Facility (NTF). The model uses a Monte Carlo technique to propagate standard uncertainties of measured values through the NTF data reduction equations to calculate the combined uncertainties of the key aerodynamic force and moment coefficients and freestream properties. The uncertainty propagation approach to assessing data variability is compared with ongoing data quality assessment activities at the NTF, notably check standard testing using statistical process control (SPC) techniques. It is shown that the two approaches are complementary and both are necessary tools for data quality assessment and improvement activities. The SPC approach is the final arbiter of variability in a facility. Its result encompasses variation due to people, processes, test equipment, and test article. The uncertainty propagation approach is limited mainly to the data reduction process. However, it is useful because it helps to assess the causes of variability seen in the data and consequently provides a basis for improvement. For example, it is shown that Mach number random uncertainty is dominated by static pressure variation over most of the dynamic pressure range tested. However, the random uncertainty in the drag coefficient is generally dominated by axial and normal force uncertainty with much less contribution from freestream conditions.

  3. Dispersal and fallout simulations for urban consequences management (u)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Grinstein, Fernando F; Wachtor, Adam J; Nelson, Matt

    2010-01-01

    Hazardous chemical, biological, or radioactive releases from leaks, spills, fires, or blasts, may occur (intentionally or accidentally) in urban environments during warfare or as part of terrorist attacks on military bases or other facilities. The associated contaminant dispersion is complex and semi-chaotic. Urban predictive simulation capabilities can have direct impact in many threat-reduction areas of interest, including, urban sensor placement and threat analysis, contaminant transport (CT) effects on surrounding civilian population (dosages, evacuation, shelter-in-place), education and training of rescue teams and services. Detailed simulations for the various processes involved are in principle possible, but generally not fast. Predicting urban airflowmore » accompanied by CT presents extremely challenging requirements. Crucial technical issues include, simulating turbulent fluid and particulate transport, initial and boundary condition modeling incorporating a consistent stratified urban boundary layer with realistic wind fluctuations, and post-processing of the simulation results for practical consequences management. Relevant fluid dynamic processes to be simulated include, detailed energetic and contaminant sources, complex building vortex shedding and flows in recirculation zones, and modeling of particle distributions, including particulate fallout, as well as deposition, re-suspension and evaporation. Other issues include, modeling building damage effects due to eventual blasts, addressing appropriate regional and atmospheric data reduction.« less

  4. From plot to regional scales: Interactions of slope and catchment hydrological and geomorphic processes in the Spanish Pyrenees

    NASA Astrophysics Data System (ADS)

    García-Ruiz, José M.; Lana-Renault, Noemí; Beguería, Santiago; Lasanta, Teodoro; Regüés, David; Nadal-Romero, Estela; Serrano-Muela, Pilar; López-Moreno, Juan I.; Alvera, Bernardo; Martí-Bono, Carlos; Alatorre, Luis C.

    2010-08-01

    The hydrological and geomorphic effects of land use/land cover changes, particularly those associated with vegetation regrowth after farmland abandonment were investigated in the Central Spanish Pyrenees. The main focus was to assess the interactions among slope, catchment, basin, and fluvial channel processes over a range of spatial scales. In recent centuries most Mediterranean mountain areas have been subjected to significant human pressure through deforestation, cultivation of steep slopes, fires, and overgrazing. Depopulation commencing at the beginning of the 20th century, and particularly since the 1960s, has resulted in farmland abandonment and a reduction in livestock numbers, and this has led to an expansion of shrubs and forests. Studies in the Central Spanish Pyrenees, based on experimental plots and catchments, in large basins and fluvial channels, have confirmed that these land use changes have had hydrological and geomorphic consequences regardless of the spatial scale considered, and that processes occurring at any particular scale can be explained by such processes acting on other scales. Studies using experimental plots have demonstrated that during the period of greatest human pressure (mainly the 18th and 19th centuries), cultivation of steep slopes caused high runoff rates and extreme soil loss. Large parts of the small catchments behaved as runoff and sediment source areas, whereas the fluvial channels of large basins showed signs of high torrentiality (braided morphology, bare sedimentary bars, instability, and prevalence of bedload transport). Depopulation has concentrated most human pressure on the valley bottoms and specific locations such as resorts, whereas the remainder of the area has been affected by an almost generalized abandonment. Subsequent plant recolonization has resulted in a reduction of overland flow and declining soil erosion. At a catchment scale this has caused a reduction in sediment sources, and channel incision in the secondary streams. At the regional scale, the most important consequences include a reduction in the frequency of floods, reduced sediment yields, increasing stabilization of fluvial channels (colonization of sedimentary bars by riparian vegetation and a reduction in the braiding index), and stabilization of alluvial fans. These results demonstrate the complexity and multiscalar nature of the interactions among land use and runoff generation, soil erosion, sediment transport, and fluvial channel dynamics, and highlight the need to adopt a multiscale approach in other mountain areas of the world.

  5. Content-addressable read/write memories for image analysis

    NASA Technical Reports Server (NTRS)

    Snyder, W. E.; Savage, C. D.

    1982-01-01

    The commonly encountered image analysis problems of region labeling and clustering are found to be cases of search-and-rename problem which can be solved in parallel by a system architecture that is inherently suitable for VLSI implementation. This architecture is a novel form of content-addressable memory (CAM) which provides parallel search and update functions, allowing speed reductions down to constant time per operation. It has been proposed in related investigations by Hall (1981) that, with VLSI, CAM-based structures with enhanced instruction sets for general purpose processing will be feasible.

  6. The Gemini Recipe System: a dynamic workflow for automated data reduction

    NASA Astrophysics Data System (ADS)

    Labrie, Kathleen; Allen, Craig; Hirst, Paul; Holt, Jennifer; Allen, River; Dement, Kaniela

    2010-07-01

    Gemini's next generation data reduction software suite aims to offer greater automation of the data reduction process without compromising the flexibility required by science programs using advanced or unusual observing strategies. The Recipe System is central to our new data reduction software. Developed in Python, it facilitates near-real time processing for data quality assessment, and both on- and off-line science quality processing. The Recipe System can be run as a standalone application or as the data processing core of an automatic pipeline. The data reduction process is defined in a Recipe written in a science (as opposed to computer) oriented language, and consists of a sequence of data reduction steps, called Primitives, which are written in Python and can be launched from the PyRAF user interface by users wishing to use them interactively for more hands-on optimization of the data reduction process. The fact that the same processing Primitives can be run within both the pipeline context and interactively in a PyRAF session is an important strength of the Recipe System. The Recipe System offers dynamic flow control allowing for decisions regarding processing and calibration to be made automatically, based on the pixel and the metadata properties of the dataset at the stage in processing where the decision is being made, and the context in which the processing is being carried out. Processing history and provenance recording are provided by the AstroData middleware, which also offers header abstraction and data type recognition to facilitate the development of instrument-agnostic processing routines.

  7. Cleaner Production of Ti Powder by a Two-Stage Aluminothermic Reduction Process

    NASA Astrophysics Data System (ADS)

    Zhao, Kun; Wang, Yaowu; Feng, Naixiang

    2017-10-01

    A two-stage aluminothermic reduction process for preparing Ti powder under vacuum conditions using Na2TiF6 was investigated. An Al-Ti master alloy and a clean cryolite were simultaneously obtained as co-products. The first-stage reduction was an exothermic process that occurred at approximately 660°C. The Al and O contents of the Ti powder product were 0.18 wt.% and 0.35 wt.%, respectively, with an average particle size <74 μm. Ti(IV), Ti(III), and metallic Ti were present in the Ti-containing cryolite produced by the first-stage reduction, at a total content of approximately 3.13 wt.%. After second-stage reduction, the Ti elemental contents of the clean cryolite were reduced to 0.002 wt.%. The Al-Ti master alloy obtained by second-stage reduction was composed of Al and TiAl3. The mechanisms involved in these reduction processes were also examined.

  8. Noise reduction characteristics of general aviation type dual-pane windows

    NASA Technical Reports Server (NTRS)

    Grosveld, F.; Navaneethan, R.; Roskam, J.

    1980-01-01

    The noise reduction characteristics of general-aviation-type, dual-pane windows in various configurations have been experimentally investigated. The effects of inner and outer pane thickness, spacing between the panes, edge conditions, inclination of the inner pane and depressurization of the air in between the panes are presented. The space in between the two window panes is sealed airtight in all cases. Results show that increasing the mass of a 'floating' window pane does not increase the noise reduction below the fundamental resonance frequency. It is concluded that the concept of depressurization of the air between thin (1/8 in) Plexiglas panes and application of multiple-freedom edge conditions for the inner pane are promising to reduce noise levels in general aviation airplanes.

  9. Genetic Architecture of Parallel Pelvic Reduction in Ninespine Sticklebacks

    PubMed Central

    Shikano, Takahito; Laine, Veronika N.; Herczeg, Gábor; Vilkki, Johanna; Merilä, Juha

    2013-01-01

    Teleost fish genomes are known to be evolving faster than those of other vertebrate taxa. Thus, fish are suited to address the extent to which the same vs. different genes are responsible for similar phenotypic changes in rapidly evolving genomes of evolutionary independent lineages. To gain insights into the genetic basis and evolutionary processes behind parallel phenotypic changes within and between species, we identified the genomic regions involved in pelvic reduction in Northern European ninespine sticklebacks (Pungitius pungitius) and compared them to those of North American ninespine and threespine sticklebacks (Gasterosteus aculeatus). To this end, we conducted quantitative trait locus (QTL) mapping using 283 F2 progeny from an interpopulation cross. Phenotypic analyses indicated that pelvic reduction is a recessive trait and is inherited in a simple Mendelian fashion. Significant QTL for pelvic spine and girdle lengths were identified in the region of the Pituitary homeobox transcription factor 1 (Pitx1) gene, also responsible for pelvic reduction in threespine sticklebacks. The fact that no QTL was observed in the region identified in the mapping study of North American ninespine sticklebacks suggests that an alternative QTL for pelvic reduction has emerged in this species within the past 1.6 million years after the split between Northern European and North American populations. In general, our study provides empirical support for the view that alternative genetic mechanisms that lead to similar phenotypes can evolve over short evolutionary time scales. PMID:23979937

  10. Using Six Sigma methodology to reduce patient transfer times from floor to critical-care beds.

    PubMed

    Silich, Stephan J; Wetz, Robert V; Riebling, Nancy; Coleman, Christine; Khoueiry, Georges; Abi Rafeh, Nidal; Bagon, Emma; Szerszen, Anita

    2012-01-01

    In response to concerns regarding delays in transferring critically ill patients to intensive care units (ICU), a quality improvement project, using the Six Sigma process, was undertaken to correct issues leading to transfer delay. To test the efficacy of a Six Sigma intervention to reduce transfer time and establish a patient transfer process that would effectively enhance communication between hospital caregivers and improve the continuum of care for patients. The project was conducted at a 714-bed tertiary care hospital in Staten Island, New York. A Six Sigma multidisciplinary team was assembled to assess areas that needed improvement, manage the intervention, and analyze the results. The Six Sigma process identified eight key steps in the transfer of patients from general medical floors to critical care areas. Preintervention data and a root-cause analysis helped to establish the goal transfer-time limits of 3 h for any individual transfer and 90 min for the average of all transfers. The Six Sigma approach is a problem-solving methodology that resulted in almost a 60% reduction in patient transfer time from a general medical floor to a critical care area. The Six Sigma process is a feasible method for implementing healthcare related quality of care projects, especially those that are complex. © 2011 National Association for Healthcare Quality.

  11. Relationship between mass-flux reduction and source-zone mass removal: analysis of field data.

    PubMed

    Difilippo, Erica L; Brusseau, Mark L

    2008-05-26

    The magnitude of contaminant mass-flux reduction associated with a specific amount of contaminant mass removed is a key consideration for evaluating the effectiveness of a source-zone remediation effort. Thus, there is great interest in characterizing, estimating, and predicting relationships between mass-flux reduction and mass removal. Published data collected for several field studies were examined to evaluate relationships between mass-flux reduction and source-zone mass removal. The studies analyzed herein represent a variety of source-zone architectures, immiscible-liquid compositions, and implemented remediation technologies. There are two general approaches to characterizing the mass-flux-reduction/mass-removal relationship, end-point analysis and time-continuous analysis. End-point analysis, based on comparing masses and mass fluxes measured before and after a source-zone remediation effort, was conducted for 21 remediation projects. Mass removals were greater than 60% for all but three of the studies. Mass-flux reductions ranging from slightly less than to slightly greater than one-to-one were observed for the majority of the sites. However, these single-snapshot characterizations are limited in that the antecedent behavior is indeterminate. Time-continuous analysis, based on continuous monitoring of mass removal and mass flux, was performed for two sites, both for which data were obtained under water-flushing conditions. The reductions in mass flux were significantly different for the two sites (90% vs. approximately 8%) for similar mass removals ( approximately 40%). These results illustrate the dependence of the mass-flux-reduction/mass-removal relationship on source-zone architecture and associated mass-transfer processes. Minimal mass-flux reduction was observed for a system wherein mass removal was relatively efficient (ideal mass-transfer and displacement). Conversely, a significant degree of mass-flux reduction was observed for a site wherein mass removal was inefficient (non-ideal mass-transfer and displacement). The mass-flux-reduction/mass-removal relationship for the latter site exhibited a multi-step behavior, which cannot be predicted using some of the available simple estimation functions.

  12. Microbial Sulfate Reduction Potential in Coal-Bearing Sediments Down to ~2.5 km below the Seafloor off Shimokita Peninsula, Japan

    PubMed Central

    Glombitza, Clemens; Adhikari, Rishi R.; Riedinger, Natascha; Gilhooly, William P.; Hinrichs, Kai-Uwe; Inagaki, Fumio

    2016-01-01

    Sulfate reduction is the predominant anaerobic microbial process of organic matter mineralization in marine sediments, with recent studies revealing that sulfate reduction not only occurs in sulfate-rich sediments, but even extends to deeper, methanogenic sediments at very low background concentrations of sulfate. Using samples retrieved off the Shimokita Peninsula, Japan, during the Integrated Ocean Drilling Program (IODP) Expedition 337, we measured potential sulfate reduction rates by slurry incubations with 35S-labeled sulfate in deep methanogenic sediments between 1276.75 and 2456.75 meters below the seafloor. Potential sulfate reduction rates were generally extremely low (mostly below 0.1 pmol cm−3 d−1) but showed elevated values (up to 1.8 pmol cm−3 d−1) in a coal-bearing interval (Unit III). A measured increase in hydrogenase activity in the coal-bearing horizons coincided with this local increase in potential sulfate reduction rates. This paired enzymatic response suggests that hydrogen is a potentially important electron donor for sulfate reduction in the deep coalbed biosphere. By contrast, no stimulation of sulfate reduction rates was observed in treatments where methane was added as an electron donor. In the deep coalbeds, small amounts of sulfate might be provided by a cryptic sulfur cycle. The isotopically very heavy pyrites (δ34S = +43‰) found in this horizon is consistent with its formation via microbial sulfate reduction that has been continuously utilizing a small, increasingly 34S-enriched sulfate reservoir over geologic time scales. Although our results do not represent in-situ activity, and the sulfate reducers might only have persisted in a dormant, spore-like state, our findings show that organisms capable of sulfate reduction have survived in deep methanogenic sediments over more than 20 Ma. This highlights the ability of sulfate-reducers to persist over geological timespans even in sulfate-depleted environments. Our study moreover represents the deepest evidence of a potential for sulfate reduction in marine sediments to date. PMID:27761134

  13. Microbial Sulfate Reduction Potential in Coal-Bearing Sediments Down to ~2.5 km below the Seafloor off Shimokita Peninsula, Japan.

    PubMed

    Glombitza, Clemens; Adhikari, Rishi R; Riedinger, Natascha; Gilhooly, William P; Hinrichs, Kai-Uwe; Inagaki, Fumio

    2016-01-01

    Sulfate reduction is the predominant anaerobic microbial process of organic matter mineralization in marine sediments, with recent studies revealing that sulfate reduction not only occurs in sulfate-rich sediments, but even extends to deeper, methanogenic sediments at very low background concentrations of sulfate. Using samples retrieved off the Shimokita Peninsula, Japan, during the Integrated Ocean Drilling Program (IODP) Expedition 337, we measured potential sulfate reduction rates by slurry incubations with 35 S-labeled sulfate in deep methanogenic sediments between 1276.75 and 2456.75 meters below the seafloor. Potential sulfate reduction rates were generally extremely low (mostly below 0.1 pmol cm -3 d -1 ) but showed elevated values (up to 1.8 pmol cm -3 d -1 ) in a coal-bearing interval (Unit III). A measured increase in hydrogenase activity in the coal-bearing horizons coincided with this local increase in potential sulfate reduction rates. This paired enzymatic response suggests that hydrogen is a potentially important electron donor for sulfate reduction in the deep coalbed biosphere. By contrast, no stimulation of sulfate reduction rates was observed in treatments where methane was added as an electron donor. In the deep coalbeds, small amounts of sulfate might be provided by a cryptic sulfur cycle. The isotopically very heavy pyrites (δ 34 S = +43‰) found in this horizon is consistent with its formation via microbial sulfate reduction that has been continuously utilizing a small, increasingly 34 S-enriched sulfate reservoir over geologic time scales. Although our results do not represent in-situ activity, and the sulfate reducers might only have persisted in a dormant, spore-like state, our findings show that organisms capable of sulfate reduction have survived in deep methanogenic sediments over more than 20 Ma. This highlights the ability of sulfate-reducers to persist over geological timespans even in sulfate-depleted environments. Our study moreover represents the deepest evidence of a potential for sulfate reduction in marine sediments to date.

  14. Weight loss and waist reduction is associated with improvement in gastroesophageal disease reflux symptoms: A longitudinal study of 15 295 subjects undergoing health checkups.

    PubMed

    Park, S-K; Lee, T; Yang, H-J; Park, J H; Sohn, C I; Ryu, S; Park, D I

    2017-05-01

    General obesity and abdominal obesity is an established risk factor of gastroesophageal reflux disease (GERD). However, the influence of weight or waist change on improvement of GERD is unclear. Our aim was to investigate if weight loss or waist reduction improves GERD symptoms and esophagitis. A retrospective longitudinal study of 15 295 subjects who underwent gastroscopy for a health checkup and reported GERD symptoms between 2011 and 2013, and repeated a checkup until 2014 was conducted. The improvement of GERD symptoms and esophagitis according to weight loss (≥-2, -0.5 to -2 kg/m 2 in body mass index [BMI]), waist reduction (≥-5, -0.1 to -0.5 cm) and baseline BMI/waist circumference (WC) categories was assessed using logistic regression. Weight loss or waist reduction was associated with improvement in GERD symptoms only in subjects with general or abdominal obesity. Among subjects with general obesity (BMI ≥25 kg/m 2 ) and decreased ≥2 kg/m 2 in BMI, the adjusted odds ratio (OR) of improvement in GERD symptoms was 2.34 (95% confidence interval [CI] 1.70-2.83). Among subjects with abdominal obesity (WC ≥90 cm) and decreased ≥5 cm in WC, the corresponding OR was 2.16 (95% CI 1.56-2.90). There was no association between weight loss or waist reduction and improvement in esophagitis. Weight loss or waist reduction was associated with improvement in GERD symptoms only in subjects with general or abdominal obesity. Weight loss or waist reduction will be an important treatment option in obese patients. © 2016 John Wiley & Sons Ltd.

  15. Effect of temperature in the selective reduction process of limonite nickel ore

    NASA Astrophysics Data System (ADS)

    Mayangsari, W.; Febriana, Eni; Prasetyo, A. B.

    2018-05-01

    Temperature is the main factor for the reduction process that influence to reduction degree, phase and morphology transformation. In order to determine these effects which is caused by reduction temperature, this study was conducted. Limoniticnickel ore was prepared by drying and size reduction. A part of prepared limonitewas characterized with XRF to determine the chemical composition. The other part was mixed with reducing agent and CaSO4 to produce pellet. A series of selective reduction processes were conducted to the pellet by using graphite crucible in the muffle furnace carbolite at 800° - 1100°C for 60 minutes. Reduced ore characterized by using XRD and SEM analysis. Based on the result study, weight loss and reduction degree increase as temperature raised along with CaSO4 addition. Moreover, it caused decomposition and transformation to the metallic phase of kamacite and iron up to 7.51% and 41.44% respectively in the reduction process at 1100°C for 60 minutes. Furthermore, particle size growth as metallic phase content increased.

  16. Response time modeling reveals multiple contextual cuing mechanisms.

    PubMed

    Sewell, David K; Colagiuri, Ben; Livesey, Evan J

    2017-08-24

    Contextual cuing refers to a response time (RT) benefit that occurs when observers search through displays that have been repeated over the course of an experiment. Although it is generally agreed that contextual cuing arises via an associative learning mechanism, there is uncertainty about the type(s) of process(es) that allow learning to influence RT. We contrast two leading accounts of the contextual cuing effect that differ in terms of the general process that is credited with producing the effect. The first, the expedited search account, attributes the cuing effect to an increase in the speed with which the target is acquired. The second, the decision threshold account, attributes the cuing effect to a reduction in the response threshold used by observers when making a subsequent decision about the target (e.g., judging its orientation). We use the diffusion model to contrast the quantitative predictions of these two accounts at the level of individual observers. Our use of the diffusion model allows us to also explore a novel decision-level locus of the cuing effect based on perceptual learning. This novel account attributes the RT benefit to a perceptual learning process that increases the quality of information used to drive the decision process. Our results reveal both individual differences in the process(es) involved in contextual cuing but also identify several striking regularities across observers. We find strong support for both the decision threshold account as well as the novel perceptual learning account. We find relatively weak support for the expedited search account.

  17. Organizational downsizing: a review of literature for planning and research.

    PubMed

    Davis, Jullet A; Savage, Grant; Stewart, R Thomas

    2003-01-01

    The use of downsizing as management's strategic response to environmental and institutional changes is prevalent in all U.S. industries, including healthcare. The popular and research literature is inundated with reports on companies undergoing various stages of restructuring, which often include one or more staff reductions. This article provides a review of downsizing literature published from 1985 to 2002. Although the findings and conclusions of these articles are generally inconsistent, the prevailing opinion is that for downsizing to be successful, effective planning must occur long before, during, and after downsizing. Additionally, a downsizing plan should be included in the strategic management plan of all organizations, regardless of whether they plan to downsize or not. By including such a plan, the organization will be better prepared to begin the staff-reduction process should it be forced to do so in response to environmental changes. Finally, providing ample support and protection for staff is key to the organization's recovery and growth. The lessons provided in this literature review should assist healthcare managers in deciding how to plan and structure potential staff reductions.

  18. Facile Reductive Silylation of UO22+ to Uranium(IV) Chloride.

    PubMed

    Kiernicki, John J; Zeller, Matthias; Bart, Suzanne C

    2017-01-19

    General reductive silylation of the UO 2 2+ cation occurs readily in a one-pot, two-step stoichiometric reaction at room temperature to form uranium(IV) siloxides. Addition of two equivalents of an alkylating reagent to UO 2 X 2 (L) 2 (X=Cl, Br, I, OTf; L=triphenylphosphine oxide, 2,2'-bipyridyl) followed by two equivalents of a silyl (pseudo)halide, R 3 Si-X (R=aryl, alkyl, H; X=Cl, Br, I, OTf, SPh), cleanly affords (R 3 SiO) 2 UX 2 (L) 2 in high yields. Support is included for the key step in the process, reduction of U VI to U V . This procedure is applicable to a wide range of commercially available uranyl salts, silyl halides, and alkylating reagents. Under this protocol, one equivalent of SiCl 4 or two equivalents of Me 2 SiCl 2 results in direct conversion of the uranyl to uranium(IV) tetrachloride. Full spectroscopic and structural characterization of the siloxide products is reported. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. Reductions in U.S. Costs to Station Forces in the Federal Republic of Germany and the United Kingdom Are Unlikely.

    DTIC Science & Technology

    1984-07-31

    AD-A144 501 REDUCTIONS IN US COSTS TO STATION FORCES IN THE FEDERAL i/’i REPUBLIC OF GERMA..(U) GENERAL ACCOUNTING OFFICE WASHINGTON DC RESOURCES...COMPTROLLER GENERAL Report To The Chairman Subcommittee On Defense, Senate p Committee On Appropriations OF THE UNITED STATES 0 lot Reductions In U.S. Costs To...reducing the costs of sta- tioning U.S. Forces in Europe through in- creased cost sharing by the European allies. The Federal Republic of Germany and

  20. Real-time data reduction capabilities at the Langley 7 by 10 foot high speed tunnel

    NASA Technical Reports Server (NTRS)

    Fox, C. H., Jr.

    1980-01-01

    The 7 by 10 foot high speed tunnel performs a wide range of tests employing a variety of model installation methods. To support the reduction of static data from this facility, a generalized wind tunnel data reduction program had been developed for use on the Langley central computer complex. The capabilities of a version of this generalized program adapted for real time use on a dedicated on-site computer are discussed. The input specifications, instructions for the console operator, and full descriptions of the algorithms are included.

  1. 26 CFR 1.1017-1 - Basis reductions following a discharge of indebtedness.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... profits of the partnership, or if reductions to the basis of the taxpayer's depreciable property (or... 26 Internal Revenue 11 2011-04-01 2011-04-01 false Basis reductions following a discharge of... Basis reductions following a discharge of indebtedness. (a) General rule for section 108(b)(2)(E). This...

  2. 26 CFR 1.1017-1 - Basis reductions following a discharge of indebtedness.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... profits of the partnership, or if reductions to the basis of the taxpayer's depreciable property (or... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Basis reductions following a discharge of... reductions following a discharge of indebtedness. (a) General rule for section 108(b)(2)(E). This paragraph...

  3. 20 CFR 226.73 - Changes in reduction amount.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Changes in reduction amount. 226.73 Section... Benefits Under a Federal, State, or Local Law or Plan § 226.73 Changes in reduction amount. The reduction amount is not changed when a tier I benefit increases because of a recomputation or a general adjustment...

  4. Integrable multi-component generalization of a modified short pulse equation

    NASA Astrophysics Data System (ADS)

    Matsuno, Yoshimasa

    2016-11-01

    We propose a multi-component generalization of the modified short pulse (SP) equation which was derived recently as a reduction of Feng's two-component SP equation. Above all, we address the two-component system in depth. We obtain the Lax pair, an infinite number of conservation laws and multisoliton solutions for the system, demonstrating its integrability. Subsequently, we show that the two-component system exhibits cusp solitons and breathers for which the detailed analysis is performed. Specifically, we explore the interaction process of two cusp solitons and derive the formula for the phase shift. While cusp solitons are singular solutions, smooth breather solutions are shown to exist, provided that the parameters characterizing the solutions satisfy certain conditions. Last, we discuss the relation between the proposed system and existing two-component SP equations.

  5. Green tea extract for periodontal health

    PubMed Central

    Venkateswara, Babu; Sirisha, K.; Chava, Vijay K.

    2011-01-01

    Tea, the commonly consumed beverage, is gaining increased attention in promoting overall health. In specific, green tea is considered a healthful beverage due to the biological activity of its polyphenols namely catechins. Among the polyphenols Epigallo catechin 3 gallate and Epicatechin 3 Gallate are the most predominant catechins. The antioxidant, antimicrobial, anticollagenase, antimutagenic, and c hemopreventive properties of these catechins proved to be helpful in the treatment of chronic diseases like periodontal disease. Studies have demonstrated that the type of processing mainly effects the concentration of catechins. Several epidemiological studies have proved that green tea also has some general health benefitting properties like antihypertensive, reduction of cardiovascular risk, antibacterial, antiviral, and antifungal activity. The present review concentrates on the effects of green tea in periodontal and general health. PMID:21772716

  6. Effects of dissolved oxygen on performance and microbial community structure in a micro-aerobic hydrolysis sludge in situ reduction process.

    PubMed

    Niu, Tianhao; Zhou, Zhen; Shen, Xuelian; Qiao, Weimin; Jiang, Lu-Man; Pan, Wei; Zhou, Jijun

    2016-03-01

    A sludge process reduction activated sludge (SPRAS), with a sludge process reduction module composed of a micro-aerobic tank and a settler positioned before conventional activated sludge process, showed good performance of pollutant removal and sludge reduction. Two SPRAS systems were operated to investigate effects of micro-aeration on sludge reduction performance and microbial community structure. When dissolved oxygen (DO) concentration in the micro-aerobic tank decreased from 2.5 (SPH) to 0.5 (SPL) mg/L, the sludge reduction efficiency increased from 42.9% to 68.3%. Compared to SPH, activated sludge in SPL showed higher contents of extracellular polymeric substances and dissolved organic matter. Destabilization of floc structure in the settler, and cell lysis in the sludge process reduction module were two major reasons for sludge reduction. Illumina-MiSeq sequencing showed that microbial diversity decreased under high DO concentration. Proteobacteria, Bacteroidetes and Chloroflexi were the most abundant phyla in the SPRAS. Specific comparisons down to the class and genus level showed that fermentative, predatory and slow-growing bacteria in SPL community were more abundant than in SPH. The results revealed that micro-aeration in the SPRAS improved hydrolysis efficiency and enriched fermentative and predatory bacteria responsible for sludge reduction. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. A sampling procedure to guide the collection of narrow-band, high-resolution spatially and spectrally representative reflectance data. [satellite imagery of earth resources

    NASA Technical Reports Server (NTRS)

    Brand, R. R.; Barker, J. L.

    1983-01-01

    A multistage sampling procedure using image processing, geographical information systems, and analytical photogrammetry is presented which can be used to guide the collection of representative, high-resolution spectra and discrete reflectance targets for future satellite sensors. The procedure is general and can be adapted to characterize areas as small as minor watersheds and as large as multistate regions. Beginning with a user-determined study area, successive reductions in size and spectral variation are performed using image analysis techniques on data from the Multispectral Scanner, orbital and simulated Thematic Mapper, low altitude photography synchronized with the simulator, and associated digital data. An integrated image-based geographical information system supports processing requirements.

  8. Development of a microcomputer-based magnetic heading sensor

    NASA Technical Reports Server (NTRS)

    Garner, H. D.

    1987-01-01

    This paper explores the development of a flux-gate magnetic heading reference using a single-chip microcomputer to process heading information and to present it to the pilot in appropriate form. This instrument is intended to replace the conventional combination of mechanical compass and directional gyroscope currently in use in general aviation aircraft, at appreciable savings in cost and reduction in maintenance. Design of the sensing element, the signal processing electronics, and the computer algorithms which calculate the magnetic heading of the aircraft from the magnetometer data have been integrated in such a way as to minimize hardware requirements and simplify calibration procedures. Damping and deviation errors are avoided by the inherent design of the device, and a technique for compensating for northerly-turning-error is described.

  9. Oscillatory Reduction in Option Pricing Formula Using Shifted Poisson and Linear Approximation

    NASA Astrophysics Data System (ADS)

    Nur Rachmawati, Ro'fah; Irene; Budiharto, Widodo

    2014-03-01

    Option is one of derivative instruments that can help investors improve their expected return and minimize the risks. However, the Black-Scholes formula is generally used in determining the price of the option does not involve skewness factor and it is difficult to apply in computing process because it produces oscillation for the skewness values close to zero. In this paper, we construct option pricing formula that involve skewness by modified Black-Scholes formula using Shifted Poisson model and transformed it into the form of a Linear Approximation in the complete market to reduce the oscillation. The results are Linear Approximation formula can predict the price of an option with very accurate and successfully reduce the oscillations in the calculation processes.

  10. Care Model Design for E-Health: Integration of Point-of-Care Testing at Dutch General Practices.

    PubMed

    Verhees, Bart; van Kuijk, Kees; Simonse, Lianne

    2017-12-21

    Point-of-care testing (POCT)-laboratory tests performed with new mobile devices and online technologies outside of the central laboratory-is rapidly outpacing the traditional laboratory test market, growing at a rate of 12 to 15% each year. POCT impacts the diagnostic process of care providers by yielding high efficiency benefits in terms of turnaround time and related quality improvements in the reduction of errors. However, the implementation of this disruptive eHealth technology requires the integration and transformation of diagnostic services across the boundaries of healthcare organizations. Research has revealed both advantages and barriers of POCT implementations, yet to date, there is no business model for the integration of POCT within general practice. The aim of this article is to contribute with a design for a care model that enables the integration of POCT in primary healthcare. In this research, we used a design modelling toolkit for data collection at five general practices. Through an iterative design process, we modelled the actors and value transactions, and designed an optimized care model for the dynamic integration of POCTs into the GP's network of care delivery. The care model design will have a direct bearing on improving the integration of POCT through the connectivity and norm guidelines between the general practice, the POC technology, and the diagnostic centre.

  11. Care Model Design for E-Health: Integration of Point-of-Care Testing at Dutch General Practices

    PubMed Central

    Verhees, Bart; van Kuijk, Kees

    2017-01-01

    Point-of-care testing (POCT)—laboratory tests performed with new mobile devices and online technologies outside of the central laboratory—is rapidly outpacing the traditional laboratory test market, growing at a rate of 12 to 15% each year. POCT impacts the diagnostic process of care providers by yielding high efficiency benefits in terms of turnaround time and related quality improvements in the reduction of errors. However, the implementation of this disruptive eHealth technology requires the integration and transformation of diagnostic services across the boundaries of healthcare organizations. Research has revealed both advantages and barriers of POCT implementations, yet to date, there is no business model for the integration of POCT within general practice. The aim of this article is to contribute with a design for a care model that enables the integration of POCT in primary healthcare. In this research, we used a design modelling toolkit for data collection at five general practices. Through an iterative design process, we modelled the actors and value transactions, and designed an optimized care model for the dynamic integration of POCTs into the GP’s network of care delivery. The care model design will have a direct bearing on improving the integration of POCT through the connectivity and norm guidelines between the general practice, the POC technology, and the diagnostic centre. PMID:29267224

  12. The role of effort in influencing the effect of anxiety on performance: testing the conflicting predictions of processing efficiency theory and the conscious processing hypothesis.

    PubMed

    Wilson, Mark; Smith, Nickolas C; Holmes, Paul S

    2007-08-01

    The aim of this study was to test the conflicting predictions of processing efficiency theory (PET) and the conscious processing hypothesis (CPH) regarding effort's role in influencing the effects of anxiety on a golf putting task. Mid-handicap golfers made a series of putts to target holes under two counterbalanced conditions designed to manipulate the level of anxiety experienced. The effort exerted on each putting task was assessed though self-report, psychophysiological (heart rate variability) and behavioural (pre-putt time and glances at the target) measures. Performance was assessed by putting error. Results were generally more supportive of the predictions of PET rather than the CPH as performance was maintained for some performers despite increased state anxiety and a reduction in processing efficiency. The findings of this study support previous research suggesting that both theories offer useful theoretical frameworks for examining the relationship between anxiety and performance in sport.

  13. The Gemini Recipe System: A Dynamic Workflow for Automated Data Reduction

    NASA Astrophysics Data System (ADS)

    Labrie, K.; Hirst, P.; Allen, C.

    2011-07-01

    Gemini's next generation data reduction software suite aims to offer greater automation of the data reduction process without compromising the flexibility required by science programs using advanced or unusual observing strategies. The Recipe System is central to our new data reduction software. Developed in Python, it facilitates near-real time processing for data quality assessment, and both on- and off-line science quality processing. The Recipe System can be run as a standalone application or as the data processing core of an automatic pipeline. Building on concepts that originated in ORAC-DR, a data reduction process is defined in a Recipe written in a science (as opposed to computer) oriented language, and consists of a sequence of data reduction steps called Primitives. The Primitives are written in Python and can be launched from the PyRAF user interface by users wishing for more hands-on optimization of the data reduction process. The fact that the same processing Primitives can be run within both the pipeline context and interactively in a PyRAF session is an important strength of the Recipe System. The Recipe System offers dynamic flow control allowing for decisions regarding processing and calibration to be made automatically, based on the pixel and the metadata properties of the dataset at the stage in processing where the decision is being made, and the context in which the processing is being carried out. Processing history and provenance recording are provided by the AstroData middleware, which also offers header abstraction and data type recognition to facilitate the development of instrument-agnostic processing routines. All observatory or instrument specific definitions are isolated from the core of the AstroData system and distributed in external configuration packages that define a lexicon including classifications, uniform metadata elements, and transformations.

  14. Antimicrobially Treated Projects for Military Use

    DTIC Science & Technology

    2007-11-30

    antimicrobial socks showed an overall reduction in the percentage of Soldiers who reported foot odor , general discomfort, and itching. There is...However, there seemed to be some impact of the sock treatments on foot odor , hygiene practices, comfort and suitability for extended wear, and...antimicrobial socks showed an overall reduction in the percentage reporting foot odor , general discomfort, and itching. Overall, it seemed that an

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rajamani, S.

    The leather industry is an important export-oriented industry in India, with more than 3,000 tanneries located in different clusters. Sodium sulfide, a toxic chemical, is used in large quantities to remove hair and excess flesh from hides and skins. Most of the sodium sulfide used in the process is discharged as waste in the effluent, which causes serious environmental problems. Reduction of sulfide in the effluent is generally achieved by means of chemicals in the pretreatment system, which involves aerobic mixing using large amounts of chemicals and high energy, and generating large volumes of sludge. A simple biotechnological system thatmore » uses the residual biosludge from the secondary settling tank was developed, and the commercial-scale application established that more than 90% of the sulfide could be reduced in the primary treatment system. In addition to the reduction of sulfide, foul smells, BOD and COD are reduced to a considerable level. 3 refs., 2 figs., 1 tab.« less

  16. Nickel-catalyzed cross-coupling of photoredox-generated radicals: uncovering a general manifold for stereoconvergence in nickel-catalyzed cross-couplings.

    PubMed

    Gutierrez, Osvaldo; Tellis, John C; Primer, David N; Molander, Gary A; Kozlowski, Marisa C

    2015-04-22

    The cross-coupling of sp(3)-hybridized organoboron reagents via photoredox/nickel dual catalysis represents a new paradigm of reactivity for engaging alkylmetallic reagents in transition-metal-catalyzed processes. Reported here is an investigation into the mechanistic details of this important transformation using density functional theory. Calculations bring to light a new reaction pathway involving an alkylnickel(I) complex generated by addition of an alkyl radical to Ni(0) that is likely to operate simultaneously with the previously proposed mechanism. Analysis of the enantioselective variant of the transformation reveals an unexpected manifold for stereoinduction involving dynamic kinetic resolution (DKR) of a Ni(III) intermediate wherein the stereodetermining step is reductive elimination. Furthermore, calculations suggest that the DKR-based stereoinduction manifold may be responsible for stereoselectivity observed in numerous other stereoconvergent Ni-catalyzed cross-couplings and reductive couplings.

  17. Loss of sea ice in the Arctic.

    PubMed

    Perovich, Donald K; Richter-Menge, Jacqueline A

    2009-01-01

    The Arctic sea ice cover is in decline. The areal extent of the ice cover has been decreasing for the past few decades at an accelerating rate. Evidence also points to a decrease in sea ice thickness and a reduction in the amount of thicker perennial sea ice. A general global warming trend has made the ice cover more vulnerable to natural fluctuations in atmospheric and oceanic forcing. The observed reduction in Arctic sea ice is a consequence of both thermodynamic and dynamic processes, including such factors as preconditioning of the ice cover, overall warming trends, changes in cloud coverage, shifts in atmospheric circulation patterns, increased export of older ice out of the Arctic, advection of ocean heat from the Pacific and North Atlantic, enhanced solar heating of the ocean, and the ice-albedo feedback. The diminishing Arctic sea ice is creating social, political, economic, and ecological challenges.

  18. Study of noise reduction characteristics of double-wall panels

    NASA Technical Reports Server (NTRS)

    Navaneethan, R.; Quayle, B.; Stevenson, S.; Graham, M.

    1983-01-01

    The noise reduction characteristics of general aviation type, flat, double-wall structures were investigated. The experimental study was carried out on 20-by-20 inch panels with an exposed area of 18 by 18 inches. A frequency range from 20 to 5000 Hz was covered. The experimental results, in general, follow the expected trends. At low frequencies the double-wall structures are no better than the single-wall structures. However, for depths normally used in the general aviation industry, the double-wall panels are very attractive. The graphite-spoxy skin panels have higher noise reduction at very low frequencies ( 100 Hz) than the Kevlar skin panels. But the aluminum panels have higher noise reduction in the high frequency region, due to their greater mass. Use of fiberglass insulation is not effective in the low frequency region, and at times it is even negative. But the insulation is effective in the high-frequency region. The theoretical model for predicting the transmission loss of these multilayered panels is also discussed.

  19. Study of noise reduction characteristics of double-wall panels

    NASA Astrophysics Data System (ADS)

    Navaneethan, R.; Quayle, B.; Stevenson, S.; Graham, M.

    1983-05-01

    The noise reduction characteristics of general aviation type, flat, double-wall structures were investigated. The experimental study was carried out on 20-by-20 inch panels with an exposed area of 18 by 18 inches. A frequency range from 20 to 5000 Hz was covered. The experimental results, in general, follow the expected trends. At low frequencies the double-wall structures are no better than the single-wall structures. However, for depths normally used in the general aviation industry, the double-wall panels are very attractive. The graphite-spoxy skin panels have higher noise reduction at very low frequencies ( 100 Hz) than the Kevlar skin panels. But the aluminum panels have higher noise reduction in the high frequency region, due to their greater mass. Use of fiberglass insulation is not effective in the low frequency region, and at times it is even negative. But the insulation is effective in the high-frequency region. The theoretical model for predicting the transmission loss of these multilayered panels is also discussed.

  20. A stage model as an analysis framework for studying voluntary change in food choices - The case of beef consumption reduction in Norway.

    PubMed

    Klöckner, Christian A

    2017-01-01

    This paper studies the application of a stage-based model of consumer behavior change on describing the processes behind the reduction of beef consumption in two Norwegian samples (N = 746, N = 2967). The way to reduce beef consumption is modeled through a progression through four stages (predecision, decision, action, and postaction) with a chain of first forming goal intentions, then more concrete behavioral intentions and finally implementation intentions. The analyzes show that general goal intentions to reduce beef consumption are determined by perceived social norms and awareness of a behaviors negative consequences through the activation of personal norms. Attitudes are the main determinant of choosing the alternative behavior (reduction of portion size, substitution of beef with other meats or seafood, or vegetarian meals), but perceived difficulty of behavior also has an impact for some alternatives. Not all alternative behaviors correspond to reduced beef consumption. The pattern of means in beef consumption and intentions for consumers in different stages of change mostly matched predictions by the model, most importantly, showing beef consumption reduction only for consumers in the last stage of change. Implications for interventions are discussed. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. A general soft label based linear discriminant analysis for semi-supervised dimensionality reduction.

    PubMed

    Zhao, Mingbo; Zhang, Zhao; Chow, Tommy W S; Li, Bing

    2014-07-01

    Dealing with high-dimensional data has always been a major problem in research of pattern recognition and machine learning, and Linear Discriminant Analysis (LDA) is one of the most popular methods for dimension reduction. However, it only uses labeled samples while neglecting unlabeled samples, which are abundant and can be easily obtained in the real world. In this paper, we propose a new dimension reduction method, called "SL-LDA", by using unlabeled samples to enhance the performance of LDA. The new method first propagates label information from the labeled set to the unlabeled set via a label propagation process, where the predicted labels of unlabeled samples, called "soft labels", can be obtained. It then incorporates the soft labels into the construction of scatter matrixes to find a transformed matrix for dimension reduction. In this way, the proposed method can preserve more discriminative information, which is preferable when solving the classification problem. We further propose an efficient approach for solving SL-LDA under a least squares framework, and a flexible method of SL-LDA (FSL-LDA) to better cope with datasets sampled from a nonlinear manifold. Extensive simulations are carried out on several datasets, and the results show the effectiveness of the proposed method. Copyright © 2014 Elsevier Ltd. All rights reserved.

  2. The Gravity Probe B `Niobium bird' experiment: Verifying the data reduction scheme for estimating the relativistic precession of Earth-orbiting gyroscopes

    NASA Technical Reports Server (NTRS)

    Uemaatsu, Hirohiko; Parkinson, Bradford W.; Lockhart, James M.; Muhlfelder, Barry

    1993-01-01

    Gravity Probe B (GP-B) is a relatively gyroscope experiment begun at Stanford University in 1960 and supported by NASA since 1963. This experiment will check, for the first time, the relativistic precession of an Earth-orbiting gyroscope that was predicted by Einstein's General Theory of Relativity, to an accuracy of 1 milliarcsecond per year or better. A drag-free satellite will carry four gyroscopes in a polar orbit to observe their relativistic precession. The primary sensor for measuring the direction of gyroscope spin axis is the SQUID (superconducting quantum interference device) magnetometer. The data reduction scheme designed for the GP-B program processes the signal from the SQUID magnetometer and estimates the relativistic precession rates. We formulated the data reduction scheme and designed the Niobium bird experiment to verify the performance of the data reduction scheme experimentally with an actual SQUID magnetometer within the test loop. This paper reports the results from the first phase of the Niobium bird experiment, which used a commercially available SQUID magnetometer as its primary sensor, and adresses the issues they raised. The first phase resulted in a large, temperature-dependent bias drift in the insensitive design and a temperature regulation scheme.

  3. 77 FR 15370 - General Services Administration Acquisition Regulation; Information Collection; Price Reductions...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-15

    ... Services Administration Acquisition Regulation; Information Collection; Price Reductions Clause; Extension... notice of request for comments regarding OMB Control No. 3090-0235, Price Reductions Clause, published in... 16, 2012. ADDRESSES: Submit comments identified by Information Collection 3090- 0235, Price...

  4. 78 FR 10135 - Fishing Capacity Reduction Program for the Longline Catcher Processor Subsector of the Bering Sea...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-13

    ... reduction loan to finance the non-pollock groundfish fishing capacity reduction program. DATES: The non... finance reduction program costs. Subpart L of 50 CFR part 600 is the framework rule generally implementing... higher fee rate will be credited to future landings. Fee collection and submission shall follow...

  5. Defense Waste Processing Facility Process Enhancements

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bricker, Jonathan

    2010-11-01

    Jonathan Bricker provides an overview of process enhancements currently being done at the Defense Waste Processing Facility (DWPF) at SRS. Some of these enhancements include: melter bubblers; reduction in water use, and alternate reductant.

  6. Mechanochemical processing for metals and metal alloys

    DOEpatents

    Froes, Francis H.; Eranezhuth, Baburaj G.; Prisbrey, Keith

    2001-01-01

    A set of processes for preparing metal powders, including metal alloy powders, by ambient temperature reduction of a reducible metal compound by a reactive metal or metal hydride through mechanochemical processing. The reduction process includes milling reactants to induce and complete the reduction reaction. The preferred reducing agents include magnesium and calcium hydride powders. A process of pre-milling magnesium as a reducing agent to increase the activity of the magnesium has been established as one part of the invention.

  7. Resist process optimization for further defect reduction

    NASA Astrophysics Data System (ADS)

    Tanaka, Keiichi; Iseki, Tomohiro; Marumoto, Hiroshi; Takayanagi, Koji; Yoshida, Yuichi; Uemura, Ryouichi; Yoshihara, Kosuke

    2012-03-01

    Defect reduction has become one of the most important technical challenges in device mass-production. Knowing that resist processing on a clean track strongly impacts defect formation in many cases, we have been trying to improve the track process to enhance customer yield. For example, residual type defect and pattern collapse are strongly related to process parameters in developer, and we have reported new develop and rinse methods in the previous papers. Also, we have reported the optimization method of filtration condition to reduce bridge type defects, which are mainly caused by foreign substances such as gels in resist. Even though we have contributed resist caused defect reduction in past studies, defect reduction requirements continue to be very important. In this paper, we will introduce further process improvements in terms of resist defect reduction, including the latest experimental data.

  8. Continuous production of fenofibrate solid lipid nanoparticles by hot-melt extrusion technology: a systematic study based on a quality by design approach.

    PubMed

    Patil, Hemlata; Feng, Xin; Ye, Xingyou; Majumdar, Soumyajit; Repka, Michael A

    2015-01-01

    This contribution describes a continuous process for the production of solid lipid nanoparticles (SLN) as drug-carrier systems via hot-melt extrusion (HME). Presently, HME technology has not been used for the manufacturing of SLN. Generally, SLN are prepared as a batch process, which is time consuming and may result in variability of end-product quality attributes. In this study, using Quality by Design (QbD) principles, we were able to achieve continuous production of SLN by combining two processes: HME technology for melt-emulsification and high-pressure homogenization (HPH) for size reduction. Fenofibrate (FBT), a poorly water-soluble model drug, was incorporated into SLN using HME-HPH methods. The developed novel platform demonstrated better process control and size reduction compared to the conventional process of hot homogenization (batch process). Varying the process parameters enabled the production of SLN below 200 nm. The dissolution profile of the FBT SLN prepared by the novel HME-HPH method was faster than that of the crude FBT and a micronized marketed FBT formulation. At the end of a 5-h in vitro dissolution study, a SLN formulation released 92-93% of drug, whereas drug release was approximately 65 and 45% for the marketed micronized formulation and crude drug, respectively. Also, pharmacokinetic study results demonstrated a statistical increase in Cmax, Tmax, and AUC0-24 h in the rate of drug absorption from SLN formulations as compared to the crude drug and marketed micronized formulation. In summary, the present study demonstrated the potential use of hot-melt extrusion technology for continuous and large-scale production of SLN.

  9. Auditory working memory load impairs visual ventral stream processing: toward a unified model of attentional load.

    PubMed

    Klemen, Jane; Büchel, Christian; Bühler, Mira; Menz, Mareike M; Rose, Michael

    2010-03-01

    Attentional interference between tasks performed in parallel is known to have strong and often undesired effects. As yet, however, the mechanisms by which interference operates remain elusive. A better knowledge of these processes may facilitate our understanding of the effects of attention on human performance and the debilitating consequences that disruptions to attention can have. According to the load theory of cognitive control, processing of task-irrelevant stimuli is increased by attending in parallel to a relevant task with high cognitive demands. This is due to the relevant task engaging cognitive control resources that are, hence, unavailable to inhibit the processing of task-irrelevant stimuli. However, it has also been demonstrated that a variety of types of load (perceptual and emotional) can result in a reduction of the processing of task-irrelevant stimuli, suggesting a uniform effect of increased load irrespective of the type of load. In the present study, we concurrently presented a relevant auditory matching task [n-back working memory (WM)] of low or high cognitive load (1-back or 2-back WM) and task-irrelevant images at one of three object visibility levels (0%, 50%, or 100%). fMRI activation during the processing of the task-irrelevant visual stimuli was measured in the lateral occipital cortex and found to be reduced under high, compared to low, WM load. In combination with previous findings, this result is suggestive of a more generalized load theory, whereby cognitive load, as well as other types of load (e.g., perceptual), can result in a reduction of the processing of task-irrelevant stimuli, in line with a uniform effect of increased load irrespective of the type of load.

  10. Research and Industrial Application of a Process for Direct Reduction of Molten High-Lead Smelting Slag

    NASA Astrophysics Data System (ADS)

    Li, Weifeng; Zhan, Jing; Fan, Yanqing; Wei, Chang; Zhang, Chuanfu; Hwang, Jiann-Yang

    2017-04-01

    A pyrometallurgical process for the direct reduction of molten high-lead smelting slag obtained by the Shuikoushan (SKS) method was reported in this article using solid anthracite as the fuel and reductant. The chemical composition, the lead phase composition, and the physical properties of the molten high-lead slag were examined. The effects of the process parameters on the recovery rate of valued metals were investigated in the laboratory. According to the experimental results, a new efficient bottom blow reduction furnace was employed in the pilot-scale test for high-lead slag reduction. The results showed the average recovery rate of lead was more than 96.0% with lower Pb and high Zn content of the reducing slag under the condition of reduction temperature 1100-1200°C, coal ratio 5.5-7.5%, reduction time 90-150 min, CaO/SiO2 ratio 0.35-0.45, and FeO/SiO2 ratio 1.4-1.55. Moreover, nearly 250 kg of standard coal per ton of crude Pb output was reduced compared with the blast furnace reduction process.

  11. Impact of a reduced red and processed meat dietary pattern on disease risks and greenhouse gas emissions in the UK: a modelling study.

    PubMed

    Aston, Louise M; Smith, James N; Powles, John W

    2012-01-01

    Consumption of red and processed meat (RPM) is a leading contributor to greenhouse gas (GHG) emissions, and high intakes of these foods increase the risks of several leading chronic diseases. The aim of this study was to use newly derived estimates of habitual meat intakes in UK adults to assess potential co-benefits to health and the environment from reduced RPM consumption. Modelling study using dietary intake data from the National Diet and Nutrition Survey of British Adults. British general population. Respondents were divided into fifths by energy-adjusted RPM intakes, with vegetarians constituting a sixth stratum. GHG emitted in supplying the diets of each stratum was estimated using data from life-cycle analyses. A feasible counterfactual UK population was specified, in which the proportion of vegetarians measured in the survey population doubled, and the remainder adopted the dietary pattern of the lowest fifth of RPM consumers. Reductions in risks of coronary heart disease, diabetes and colorectal cancer, and GHG emissions, under the counterfactual. Habitual RPM intakes were 2.5 times higher in the top compared with the bottom fifth of consumers. Under the counterfactual, statistically significant reductions in population aggregate risks ranged from 3.2% (95% CI 1.9 to 4.7) for diabetes in women to 12.2% (6.4 to 18.0) for colorectal cancer in men, with those moving from the highest to lowest consumption levels gaining about twice these averages. The expected reduction in GHG emissions was 0.45 tonnes CO(2) equivalent/person/year, about 3% of the current total, giving a reduction across the UK population of 27.8 million tonnes/year. Reduced consumption of RPM would bring multiple benefits to health and environment.

  12. Oxygen Reduction Reaction on Graphene in an Electro-Fenton System: In Situ Generation of H2 O2 for the Oxidation of Organic Compounds.

    PubMed

    Chen, Chen-Yu; Tang, Cheng; Wang, Hao-Fan; Chen, Cheng-Meng; Zhang, Xiaoyuan; Huang, Xia; Zhang, Qiang

    2016-05-23

    Fenton oxidation using an aqueous mixture of Fe(2+) and H2 O2 is a promising environmental remediation strategy. However, the difficulty of storage and shipment of concentrated H2 O2 and the generation of iron sludge limit its broad application. Therefore, highly efficient and cost-effective electrocatalysts are in great need. Herein, a graphene catalyst is proposed for the electro-Fenton process, in which H2 O2 is generated in situ by the two-electron reduction of the dissolved O2 on the cathode and then decomposes to generate (.) OH in acidic solution with Fe(2+) . The π bond of the oxygen is broken whereas the σ bond is generally preserved on the metal-free reduced graphene oxide owing to the high free energy change. Consequently, the oxygen is reduced to H2 O2 through a two-electron pathway. The thermally reduced graphene with a high specific surface area (308.8 m(2)  g(-1) ) and a large oxygen content (10.3 at %) exhibits excellent reactivity for the two-electron oxygen reduction reaction to H2 O2 . A highly efficient peroxide yield (64.2 %) and a remarkable decolorization of methylene blue (12 mg L(-1) ) of over 97 % in 160 min are obtained. The degradation of methylene blue with hydroxyl radicals generated in situ is described by a pseudo first-order kinetics model. This provides a proof-of-concept of an environmentally friendly electro-Fenton process using graphene for the oxygen reduction reaction in an acidic solution to generate H2 O2 . © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Rubisco, Rubisco activase, and global climate change.

    PubMed

    Sage, Rowan F; Way, Danielle A; Kubien, David S

    2008-01-01

    Global warming and the rise in atmospheric CO(2) will increase the operating temperature of leaves in coming decades, often well above the thermal optimum for photosynthesis. Presently, there is controversy over the limiting processes controlling photosynthesis at elevated temperature. Leading models propose that the reduction in photosynthesis at elevated temperature is a function of either declining capacity of electron transport to regenerate RuBP, or reductions in the capacity of Rubisco activase to maintain Rubisco in an active configuration. Identifying which of these processes is the principal limitation at elevated temperature is complicated because each may be regulated in response to a limitation in the other. Biochemical and gas exchange assessments can disentangle these photosynthetic limitations; however, comprehensive assessments are often difficult and, for many species, virtually impossible. It is proposed that measurement of the initial slope of the CO(2) response of photosynthesis (the A/C(i) response) can be a useful means to screen for Rubisco activase limitations. This is because a reduction in the Rubisco activation state should be most apparent at low CO(2) when Rubisco capacity is generally limiting. In sweet potato, spinach, and tobacco, the initial slope of the A/C(i) response shows no evidence of activase limitations at high temperature, as the slope can be accurately modelled using the kinetic parameters of fully activated Rubisco. In black spruce (Picea mariana), a reduction in the initial slope above 30 degrees C cannot be explained by the known kinetics of fully activated Rubisco, indicating that activase may be limiting at high temperatures. Because black spruce is the dominant species in the boreal forest of North America, Rubisco activase may be an unusually important factor determining the response of the boreal biome to climate change.

  14. 36 CFR 218.6 - Reviewing officer.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ADMINISTRATIVE REVIEW PROCESSES Predecisional Administrative Review Process for Hazardous Fuel Reduction Projects... the administrative review processes of other Federal agencies, for authorized hazardous fuel reduction... administrative review. ...

  15. Control of fumonisin: effects of processing.

    PubMed Central

    Saunders, D S; Meredith, F I; Voss, K A

    2001-01-01

    Of about 10 billion bushels of corn that are grown each year in the United States, less than 2% is processed directly into food products, and about 18% is processed into intermediates such as high-fructose corn syrup, ethanol, and cornstarch. The vast majority of the annual crop is used domestically for animal feed (60%), and about 16% is exported. Thus, any program for controlling residues of fumonisin (FB) in food must recognize that most of the crop is grown for something other than food. Studies on the effects of wet milling on FB residues found these residues nondetectable in cornstarch, the starting material for high-fructose corn syrup and most other wet-milled food ingredients. Similar effects are noted for the dry-milling process. FB residues were nondetectable or quite low in dry flaking grits and corn flour, higher in corn germ, and highest in corn bran. Extrusion of dry-milled products reduces FB concentrations by 30-90% for mixing-type extruders and 20-50% for nonmixing extruders. Cooking and canning generally have little effect on FB content. In the masa process measurable FB is reduced following the cooking, soaking, and washing steps, with little conversion of FB to the hydrolyzed form. Sheeting, baking, and frying at commercial times and temperatures generally have no effect. In summary, all available studies on the effects of processing corn into food and food ingredients consistently demonstrate substantial reductions in measurable FB. No studies have shown a concentration in FB residues in food products or ingredients. PMID:11359704

  16. Harm reduction in name, but not substance: a comparative analysis of current Canadian provincial and territorial policy frameworks.

    PubMed

    Hyshka, Elaine; Anderson-Baron, Jalene; Karekezi, Kamagaju; Belle-Isle, Lynne; Elliott, Richard; Pauly, Bernie; Strike, Carol; Asbridge, Mark; Dell, Colleen; McBride, Keely; Hathaway, Andrew; Wild, T Cameron

    2017-07-26

    In Canada, funding, administration, and delivery of health services-including those targeting people who use drugs-are primarily the responsibility of the provinces and territories. Access to harm reduction services varies across jurisdictions, possibly reflecting differences in provincial and territorial policy commitments. We examined the quality of current provincial and territorial harm reduction policies in Canada, relative to how well official documents reflect internationally recognized principles and attributes of a harm reduction approach. We employed an iterative search and screening process to generate a corpus of 54 provincial and territorial harm reduction policy documents that were current to the end of 2015. Documents were content-analyzed using a deductive coding framework comprised of 17 indicators that assessed the quality of policies relative to how well they described key population and program aspects of a harm reduction approach. Only two jurisdictions had current provincial-level, stand-alone harm reduction policies; all other documents were focused on either substance use, addiction and/or mental health, or sexually transmitted and/or blood-borne infections. Policies rarely named specific harm reduction interventions and more frequently referred to generic harm reduction programs or services. Only one document met all 17 indicators. Very few documents acknowledged that stigma and discrimination are issues faced by people who use drugs, that not all substance use is problematic, or that people who use drugs are legitimate participants in policymaking. A minority of documents recognized that abstaining from substance use is not required to receive services. Just over a quarter addressed the risk of drug overdose, and even fewer acknowledged the need to apply harm reduction approaches to an array of drugs and modes of use. Current provincial and territorial policies offer few robust characterizations of harm reduction or go beyond rhetorical or generic support for the approach. By endorsing harm reduction in name, but not in substance, provincial and territorial policies may communicate to diverse stakeholders a general lack of support for key aspects of the approach, potentially challenging efforts to expand harm reduction services.

  17. Reduction of Large Dynamical Systems by Minimization of Evolution Rate

    NASA Technical Reports Server (NTRS)

    Girimaji, Sharath S.

    1999-01-01

    Reduction of a large system of equations to a lower-dimensional system of similar dynamics is investigated. For dynamical systems with disparate timescales, a criterion for determining redundant dimensions and a general reduction method based on the minimization of evolution rate are proposed.

  18. Integrated modeling approach using SELECT and SWAT models to simulate source loading and in-stream conditions of fecal indicator bacteria.

    NASA Astrophysics Data System (ADS)

    Ranatunga, T.

    2016-12-01

    Modeling of fate and transport of fecal bacteria in a watershed is generally a processed based approach that considers releases from manure, point sources, and septic systems. Overland transport with water and sediments, infiltration into soils, transport in the vadose zone and groundwater, die-off and growth processes, and in-stream transport are considered as the other major processes in bacteria simulation. This presentation will discuss a simulation of fecal indicator bacteria (E.coli) source loading and in-stream conditions of a non-tidal watershed (Cedar Bayou Watershed) in South Central Texas using two models; Spatially Explicit Load Enrichment Calculation Tool (SELECT) and Soil and Water Assessment Tool (SWAT). Furthermore, it will discuss a probable approach of bacteria source load reduction in order to meet the water quality standards in the streams. The selected watershed is listed as having levels of fecal indicator bacteria that posed a risk for contact recreation and wading by the Texas Commission of Environmental Quality (TCEQ). The SELECT modeling approach was used in estimating the bacteria source loading from land categories. Major bacteria sources considered were, failing septic systems, discharges from wastewater treatment facilities, excreta from livestock (Cattle, Horses, Sheep and Goat), excreta from Wildlife (Feral Hogs, and Deer), Pet waste (mainly from Dogs), and runoff from urban surfaces. The estimated source loads were input to the SWAT model in order to simulate the transport through the land and in-stream conditions. The calibrated SWAT model was then used to estimate the indicator bacteria in-stream concentrations for future years based on H-GAC's regional land use, population and household projections (up to 2040). Based on the in-stream reductions required to meet the water quality standards, the corresponding required source load reductions were estimated.

  19. ORAC-DR: Overview and General Introduction

    NASA Astrophysics Data System (ADS)

    Economou, Frossie; Jenness, Tim; Currie, Malcolm J.; Adamson, Andy; Allan, Alasdair; Cavanagh, Brad

    ORAC-DR is a general purpose automatic data reduction pipeline environment. It currently supports data reduction for the United Kingdom Infrared Telescope (UKIRT) instruments UFTI, IRCAM, UIST and CGS4, for the James Clerk Maxwell Telescope (JCMT) instrument SCUBA, for the William Herschel Telescope (WHT) instrument INGRID, for the European Southern Observatory (ESO) instrument ISAAC and for the Anglo-Australian Telescope (AAT) instrument IRIS-2. This document describes the general pipeline environment. For specific information on how to reduce the data for a particular instrument, please consult the appropriate ORAC-DR instrument guide.

  20. Development of a residual acceleration data reduction and dissemination plan

    NASA Technical Reports Server (NTRS)

    Rogers, Melissa J. B.

    1992-01-01

    A major obstacle in evaluating the residual acceleration environment in an orbiting space laboratory is the amount of data collected during a given mission: gigabytes of data will be available as SAMS units begin to fly regularly. Investigators taking advantage of the reduced gravity conditions of space should not be overwhelmed by the accelerometer data which describe these conditions. We are therefore developing a data reduction and analysis plan that will allow principal investigators of low-g experiments to create experiment-specific residual acceleration data bases for post-flight analysis. The basic aspects of the plan can also be used to characterize the acceleration environment of earth orbiting laboratories. Our development of the reduction plan is based on the following program of research: the identification of experiment sensitivities by order of magnitude estimates and numerical modelling; evaluation of various signal processing techniques appropriate for the reduction, supplementation, and dissemination of residual acceleration data; and testing and implementation of the plan on existing acceleration data bases. The orientation of the residual acceleration vector with respect to some set of coordinate axes is important for experiments with known directional sensitivity. Orientation information can be obtained from the evaluation of direction cosines. Fourier analysis is commonly used to transform time history data into the frequency domain. Common spectral representations are the amplitude spectrum which gives the average of the components of the time series at each frequency and the power spectral density which indicates the power or energy present in the series per unit frequency interval. The data reduction and analysis scheme developed involves a two tiered structure to: (1) identify experiment characteristics and mission events that can be used to limit the amount of accelerator data an investigator should be interested in; and (2) process the data in a way that will be meaningful to the experiment objectives. A general outline of the plan is given.

  1. 10 CFR 9.43 - Processing requests for a waiver or reduction of fees.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Processing requests for a waiver or reduction of fees. 9.43 Section 9.43 Energy NUCLEAR REGULATORY COMMISSION PUBLIC RECORDS Freedom of Information Act Regulations § 9.43 Processing requests for a waiver or reduction of fees. (a) Within 20 working days after...

  2. 10 CFR 9.43 - Processing requests for a waiver or reduction of fees.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Processing requests for a waiver or reduction of fees. 9.43 Section 9.43 Energy NUCLEAR REGULATORY COMMISSION PUBLIC RECORDS Freedom of Information Act Regulations § 9.43 Processing requests for a waiver or reduction of fees. (a) Within 20 working days after...

  3. 10 CFR 9.43 - Processing requests for a waiver or reduction of fees.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Processing requests for a waiver or reduction of fees. 9.43 Section 9.43 Energy NUCLEAR REGULATORY COMMISSION PUBLIC RECORDS Freedom of Information Act Regulations § 9.43 Processing requests for a waiver or reduction of fees. (a) Within 20 working days after...

  4. 10 CFR 9.43 - Processing requests for a waiver or reduction of fees.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Processing requests for a waiver or reduction of fees. 9.43 Section 9.43 Energy NUCLEAR REGULATORY COMMISSION PUBLIC RECORDS Freedom of Information Act Regulations § 9.43 Processing requests for a waiver or reduction of fees. (a) Within 20 working days after...

  5. 10 CFR 9.43 - Processing requests for a waiver or reduction of fees.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Processing requests for a waiver or reduction of fees. 9.43 Section 9.43 Energy NUCLEAR REGULATORY COMMISSION PUBLIC RECORDS Freedom of Information Act Regulations § 9.43 Processing requests for a waiver or reduction of fees. (a) Within 20 working days after...

  6. 47 CFR 0.231 - Authority delegated.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... of the General Counsel, to determine, in accordance with generally accepted accounting principles for... Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION Delegations of Authority... concurrence of the General Counsel, is delegated authority to act upon requests for waiver, reduction or...

  7. Mitochondrial targeting of the human peptide methionine sulfoxide reductase (MSRA), an enzyme involved in the repair of oxidized proteins.

    PubMed

    Hansel, Alfred; Kuschel, Lioba; Hehl, Solveig; Lemke, Cornelius; Agricola, Hans-Jürgen; Hoshi, Toshinori; Heinemann, Stefan H

    2002-06-01

    Peptide methionine sulfoxide reductase (MSRA) catalyzes the reduction of methionine sulfoxide to methionine. This widely expressed enzyme constitutes an important repair mechanism for oxidatively damaged proteins, which accumulate during the manifestation of certain degenerative diseases and aging processes. In addition, it is discussed to be involved in regulatory processes. Here we address the question of how the enzyme's diverse functions are reflected in its subcellular localization. Using fusions of the human version of MSRA with the enhanced green fluorescence protein expressed in various mammalian cell lines, we show a distinct localization at mitochondria. The N-terminal 23 amino acid residues contain the signal for this mitochondrial targeting. Activity tests showed that they are not required for enzyme function. Mitochondrial localization of native MSRA in mouse and rat liver slices was verified with an MSRA-specific antibody by using immunohistochemical methods. The protein was located in the mitochondrial matrix, as demonstrated by using pre-embedding immunostaining and electron microscopy. Mitochondria are the major source of reactive oxygen species (ROS). Therefore, MSRA has to be considered an important means for the general reduction of ROS release from mitochondria.

  8. Monitoring dynamic electrochemical processes with in situ ptychography

    NASA Astrophysics Data System (ADS)

    Kourousias, George; Bozzini, Benedetto; Jones, Michael W. M.; Van Riessen, Grant A.; Dal Zilio, Simone; Billè, Fulvio; Kiskinova, Maya; Gianoncelli, Alessandra

    2018-03-01

    The present work reports novel soft X-ray Fresnel CDI ptychography results, demonstrating the potential of this method for dynamic in situ studies. Specifically, in situ ptychography experiments explored the electrochemical fabrication of Co-doped Mn-oxide/polypyrrole nanocomposites for sustainable and cost-effective fuel-cell air-electrodes. Oxygen-reduction catalysts based on Mn-oxides exhibit relatively high activity, but poor durability: doping with Co has been shown to improve both reduction rate and stability. In this study, we examine the chemical state distribution of the catalytically crucial Co dopant to elucidate details of the Co dopant incorporation into the Mn/polymer matrix. The measurements were performed using a custom-made three-electrode thin-layer microcell, developed at the TwinMic beamline of Elettra Synchrotron during a series of experiments that were continued at the SXRI beamline of the Australian Synchrotron. Our time-resolved ptychography-based investigation was carried out in situ after two representative growth steps, controlled by electrochemical bias. In addition to the observation of morphological changes, we retrieved the spectroscopic information, provided by multiple ptychographic energy scans across Co L3-edge, shedding light on the doping mechanism and demonstrating a general approach for the molecular-level investigation complex multimaterial electrodeposition processes.

  9. Permissibility of Multifetal Pregnancy Reduction from The Shiite Point of View

    PubMed Central

    Zabihi Bidgoli, Atefeh; Ardbili, Faezeh Azimzadeh

    2017-01-01

    Background Advancements in medical technology have significantly increased the possibility of successful infertility treatment. Medical interventions in the initial process of pregnancy that intend to increase the chances of pregnancy create the risk of multifetal pregnancies for both mothers and fetuses. Physicians attempt to reduce the numbers of fetuses in order to decrease this risk and guarantee the continuation of pregnancy. The aim of this paper is to understand the Shiite instruction in terms of the risks multifetal pregnancies have for fetuses and if it is permissible to reduce the numbers of fetuses. An affirmative answer will lead to the development of Islamic criteria for reduction of the number of embryos. Materials and Methods This analytical-descriptive research gathered relevant data as a literature search. We reviewed a number of Islamic resources that pertained to the fetus; after a description of the fundamentals and definitions, we subsequently analyzed juridical texts. The order of reduction was inevitably determined by taking into consideration the rules that governed the abortion provisions or general juridical rules. We also investigated the UK law as a comparison to the Shiite perspective. Results The primary ordinance states that termination of an embryo is not permitted and is considered taboo. However, fetal reductions that occur in emergency situations where there is no option or ordinary indication are permitted before the time of ensoulment. The goal of reduction can be chosen from different ways. Conclusion According to Shiite sources, fetal reduction is permitted. Defective fetuses are the criteria for selective reduction. If none are defective, the criteria are possibility and facility. But if the possibility of selection is equally for more than one fetus, the criterion is importance (for example one fetus is healthier). PMID:28042419

  10. Permissibility of Multifetal Pregnancy Reduction from The Shiite Point of View.

    PubMed

    Zabihi Bidgoli, Atefeh; Ardbili, Faezeh Azimzadeh

    2017-01-01

    Advancements in medical technology have significantly increased the possibility of successful infertility treatment. Medical interventions in the initial process of pregnancy that intend to increase the chances of pregnancy create the risk of multifetal pregnancies for both mothers and fetuses. Physicians attempt to reduce the numbers of fetuses in order to decrease this risk and guarantee the continuation of pregnancy. The aim of this paper is to understand the Shiite instruction in terms of the risks multifetal pregnancies have for fetuses and if it is permissible to reduce the numbers of fetuses. An affirmative answer will lead to the development of Islamic criteria for reduction of the number of embryos. This analytical-descriptive research gathered relevant data as a literature search. We reviewed a number of Islamic resources that pertained to the fetus; after a description of the fundamentals and definitions, we subsequently analyzed juridical texts. The order of reduction was inevitably determined by taking into consideration the rules that governed the abortion provisions or general juridical rules. We also investigated the UK law as a comparison to the Shiite perspective. The primary ordinance states that termination of an embryo is not permitted and is considered taboo. However, fetal reductions that occur in emergency situations where there is no option or ordinary indication are permitted before the time of ensoulment. The goal of reduction can be chosen from different ways. According to Shiite sources, fetal reduction is permitted. Defective fetuses are the criteria for selective reduction. If none are defective, the criteria are possibility and facility. But if the possibility of selection is equally for more than one fetus, the criterion is importance (for example one fetus is healthier).

  11. Combined Effect of Ultrasound and Mild Temperatures on the Inactivation of E. coli in Fresh Carrot Juice and Changes on its Physicochemical Characteristics.

    PubMed

    Pokhrel, Prashant Raj; Bermúdez-Aguirre, Daniela; Martínez-Flores, Héctor E; Garnica-Romo, M Guadalupe; Sablani, Shyam; Tang, Juming; Barbosa-Cánovas, Gustavo V

    2017-10-01

    The combination of ultrasound and mild temperatures to process fruits and vegetables juices is a novel approach that is showing promising results for microbial inactivation and preservation of bioactive compounds and sensory attributes. This study centers on investigating the inactivation of Escherichia coli (ATCC 11755) in carrot juice as a result of the combined effect of ultrasound (24 kHz frequency, 120 μm, and 400 W) with temperature (50, 54, and 58 °C) and processing time (0 to 10 min). In addition, the possible changes in physicochemical properties and the retention of bioactive compounds after processing were analyzed. Microbial inactivation with ultrasound treatment at 50 °C resulted in 3.5 log reduction after 10 min, whereas at 54 °C almost 5 log reduction was attained in the same period of time; meanwhile, for treatment at 58 °C, no viable cells were detected (>5 log reduction) after 2 min. There was no significant difference (P > 0.05) on pH (6.80 to 6.82), °Brix (8.0 to 8.5), titratable acidity (0.29% to 0.30%), total carotenoid (1774 to 1835 μg/100 mL), phenolic compounds (20.19 to 20.63 μg/mL), ascorbic acid (4.8 mg/100 mL), and color parameters between fresh and ultrasound treated samples at the studied temperatures. To predict the inactivation patterns, observed values were tested using 3 different general models: first-order, Weibull distribution, and biphasic. The Weibull and biphasic models show good correlation for inactivation under all processing conditions. Results show ultrasound in combination with mild temperature could be effectively used to process fresh carrot juice providing a safe product without affecting physicochemical characteristics. The combination of ultrasound and mild temperatures is effective in reducing microbial load in carrot juice to safe levels. This combination would be beneficial in the industrial processing of carrot juice without altering the quality attributes or bioactive compounds. © 2017 Institute of Food Technologists®.

  12. Clinical audits: A practical strategy for reducing cesarean section rates in a general hospital in Tehran, Iran.

    PubMed

    Mohammadi, Soheila; Källestål, Carina; Essén, Birgitta

    2012-01-01

    To investigate whether the introduction of clinical audits by the Safe Motherhood Committee of a general hospital in Tehran, Iran, influenced cesarean section (CS) rates, A retrospective study was performed. The number of deliveries before and after the institution of clinical audits (May to December 2005) were tabulated in the audited hospital and analyzed by Chi(2) test. Additionally, CS rates were measured in 3 other general hospitals during the same time period for comparison. A total of 3,494 deliveries were recorded during the study periods in 2004 and 2005 at the audited hospital. Subsequent to the audit, the overall CS rate decreased from 40% to 33% (p < 0.001) and the primary CS rate from 29% to 21% (p < 0.001), accounting for a 27% reduction in the risk of primary CS. In 2006 CS rates reverted to 42%. None of the other 3 general hospitals indicated a decline in CS rates in 2005. Our findings show a preventive association between the clinical audits and CS rates in a general hospital. The implementation of a clinical audit process can be an effective way to track care pathways and reduce unnecessary CS deliveries.

  13. Cure-WISE: HETDEX data reduction with Astro-WISE

    NASA Astrophysics Data System (ADS)

    Snigula, J. M.; Cornell, M. E.; Drory, N.; Fabricius, Max.; Landriau, M.; Hill, G. J.; Gebhardt, K.

    2012-09-01

    The Hobby-Eberly Telescope Dark Energy Experiment (HETDEX) is a blind spectroscopic survey to map the evolution of dark energy using Lyman-alpha emitting galaxies at redshifts 1:9 < z < 3:5 as tracers. The survey instrument, VIRUS, consists of 75 IFUs distributed across the 22-arcmin field of the upgraded 9.2-m HET. Each exposure gathers 33,600 spectra. Over the projected five year run of the survey we expect about 170 GB of data per night. For the data reduction we developed the Cure pipeline. Cure is designed to automatically find and calibrate the observed spectra, subtract the sky background, and detect and classify different types of sources. Cure employs rigorous statistical methods and complete pixel-level error propagation throughout the reduction process to ensure Poisson-limited performance and meaningful significance values. To automate the reduction of the whole dataset we implemented the Cure pipeline in the Astro-WISE framework. This integration provides for HETDEX a database backend with complete dependency tracking of the various reduction steps, automated checks, and a searchable interface to the detected sources and user management. It can be used to create various web interfaces for data access and quality control. Astro-WISE allows us to reduce the data from all the IFUs in parallel on a compute cluster. This cluster allows us to reduce the observed data in quasi real time and still have excess capacity for rerunning parts of the reduction. Finally, the Astro-WISE interface will be used to provide access to reduced data products to the general community.

  14. Posterior dental size reduction in hominids: the Atapuerca evidence.

    PubMed

    Bermúdez de Castro, J M; Nicolas, M E

    1995-04-01

    In order to reassess previous hypotheses concerning dental size reduction of the posterior teeth during Pleistocene human evolution, current fossil dental evidence is examined. This evidence includes the large sample of hominid teeth found in recent excavations (1984-1993) in the Sima de los Huesos Middle Pleistocene cave site of the Sierra de Atapuerca (Burgos, Spain). The lower fourth premolars and molars of the Atapuerca hominids, probably older than 300 Kyr, have dimensions similar to those of modern humans. Further, these hominids share the derived state of other features of the posterior teeth with modern humans, such as a similar relative molar size and frequent absence of the hypoconulid, thus suggesting a possible case of parallelism. We believe that dietary changes allowed size reduction of the posterior teeth during the Middle Pleistocene, and the present evidence suggests that the selective pressures that operated on the size variability of these teeth were less restrictive than what is assumed by previous models of dental reduction. Thus, the causal relationship between tooth size decrease and changes in food-preparation techniques during the Pleistocene should be reconsidered. Moreover, the present evidence indicates that the differential reduction of the molars cannot be explained in terms of restriction of available growth space. The molar crown area measurements of a modern human sample were also investigated. The results of this study, as well as previous similar analyses, suggest that a decrease of the rate of cell proliferation, which affected the later-forming crown regions to a greater extent, may be the biological process responsible for the general and differential dental size reduction that occurred during human evolution.

  15. Aging affects neural precision of speech encoding

    PubMed Central

    Anderson, Samira; Parbery-Clark, Alexandra; White-Schwoch, Travis; Kraus, Nina

    2012-01-01

    Older adults frequently report they can hear what is said but cannot understand the meaning, especially in noise. This difficulty may arise from the inability to process rapidly changing elements of speech. Aging is accompanied by a general slowing of neural processing and decreased neural inhibition, both of which likely interfere with temporal processing in auditory and other sensory domains. Age-related reductions in inhibitory neurotransmitter levels and delayed neural recovery can contribute to decreases in the auditory system’s temporal precision. Decreased precision may lead to neural timing delays, reductions in neural response magnitude, and a disadvantage in processing the rapid acoustic changes in speech. The auditory brainstem response (ABR), a scalp-recorded electrical potential, is known for its ability to capture precise neural synchrony within subcortical auditory nuclei; therefore, we hypothesized that a loss of temporal precision results in subcortical timing delays and decreases in response consistency and magnitude. To assess this hypothesis, we recorded ABRs to the speech syllable /da/ in normal hearing younger (ages 18 to 30) and older adult humans (60 to 67). Older adults had delayed ABRs, especially in response to the rapidly changing formant transition, and greater response variability. We also found that older adults had decreased phase locking and smaller response magnitudes than younger adults. Taken together, our results support the theory that older adults have a loss of temporal precision in subcortical encoding of sound, which may account, at least in part, for their difficulties with speech perception. PMID:23055485

  16. A general model for techno-economic analysis of CSP plants with thermochemical energy storage systems

    NASA Astrophysics Data System (ADS)

    Peng, Xinyue; Maravelias, Christos T.; Root, Thatcher W.

    2017-06-01

    Thermochemical energy storage (TCES), with high energy density and wide operating temperature range, presents a potential solution for CSP plant energy storage. We develop a general optimization based process model for CSP plants employing a wide range of TCES systems which allows us to assess the plant economic feasibility and energy efficiency. The proposed model is applied to a 100 MW CSP plant employing ammonia or methane TCES systems. The methane TCES system with underground gas storage appears to be the most promising option, achieving a 14% LCOE reduction over the current two-tank molten-salt CSP plants. For general TCES systems, gas storage is identified as the main cost driver, while the main energy driver is the compressor electricity consumption. The impacts of separation and different reaction parameters are also analyzed. This study demonstrates that the realization of TCES systems for CSP plants is contingent upon low storage cost and a reversible reaction with proper reaction properties.

  17. Processing, structure, and characterizaton of nickel-alumina composites obtained by the partial reduction of zirconia-doped nickel-aluminum oxide and application to the tempering of ceramics

    NASA Astrophysics Data System (ADS)

    Barbieri, Thomas John

    1999-11-01

    Partial reduction of the spinel compound NiAl2O4 results in a two phase composite mixture of Ni + Al2O3. The reduction reaction has a volume decrease associated with it, which theoretically could generate large residual stresses, which have the potential to "temper" a ceramic, i.e. to place the surface of a ceramic component into a state of residual compression. As the first step towards tempering a ceramic, it is necessary to demonstrate that appreciable stresses can be generated by this volume change, since they may be relieved by either cracking or diffusional relaxation processes at the high temperature of the reduction reaction. It was necessary to determine the best processing methods to use for producing the tempered specimens. Results are presented from a systematic study on the effect of the variation of processing parameters on the reduction behavior of NiAl2O4 doped with ZrO2. Specimen characteristics of interest were time required for reduction, microstructural development, volume contraction achieved and porosity generated during reduction, and the ability to survive the reduction process without fracturing. These results were applied to the tempering process. A simple specimen geometry was used for tempering which involved an Al 2O3 cylinder bonded to an outer NiAl2O4 ring. Finite element calculations were performed to predict the residual stresses generated by the volume contraction of the ring and the coefficient of thermal expansion, (CTE) mismatch between the Al2O3 core and the reduced composite ring. Stress measurements performed on the Al2 O3 core of each specimen using the "d vs. Sin 2Psi" method of X-ray diffraction indicate that only the CTE-induced stresses remain in the specimens after completion of the tempering process. Microstructural analysis of the tempered specimens was performed to determine if residual stresses were developed during reduction, and what processes occurred to relieve these stresses. The results indicate that stresses are generated during the reduction process, but they are dissipated through catastrophic fracture, cation rearrangement in the lattice, and creep. Further evidence of the presence of residual stresses during reduction was found in a decrease in coarsening rate in tempered specimens.

  18. Internally coated air-cooled gas turbine blading

    NASA Technical Reports Server (NTRS)

    Hsu, L.; Stevens, W. G.; Stetson, A. R.

    1979-01-01

    Ten candidate modified nickel-aluminide coatings were developed using the slip pack process. These coatings contain additives such as silicon, chromium and columbium in a nickel-aluminum coating matrix with directionally solidified MAR-M200 + Hf as the substrate alloy. Following a series of screening tests which included strain tolerance, dynamic oxidation and hot corrosion testing, the Ni-19A1-1Cb (nominal composition) coating was selected for application to the internal passages of four first-stage turbine blades. Process development results indicate that a dry pack process is suitable for internal coating application resulting in 18 percent or less reduction in air flow. Coating uniformity, based on coated air-cooled blades, was within + or - 20 percent. Test results show that the presence of additives (silicon, chromium or columbium) appeared to improve significantly the ductility of the NiA1 matrix. However, the environmental resistance of these modified nickel-aluminides were generally inferior to the simple aluminides.

  19. Dimension reduction for stochastic dynamical systems forced onto a manifold by large drift: a constructive approach with examples from theoretical biology

    NASA Astrophysics Data System (ADS)

    Parsons, Todd L.; Rogers, Tim

    2017-10-01

    Systems composed of large numbers of interacting agents often admit an effective coarse-grained description in terms of a multidimensional stochastic dynamical system, driven by small-amplitude intrinsic noise. In applications to biological, ecological, chemical and social dynamics it is common for these models to posses quantities that are approximately conserved on short timescales, in which case system trajectories are observed to remain close to some lower-dimensional subspace. Here, we derive explicit and general formulae for a reduced-dimension description of such processes that is exact in the limit of small noise and well-separated slow and fast dynamics. The Michaelis-Menten law of enzyme-catalysed reactions, and the link between the Lotka-Volterra and Wright-Fisher processes are explored as a simple worked examples. Extensions of the method are presented for infinite dimensional systems and processes coupled to non-Gaussian noise sources.

  20. Mesoporous gold sponges: electric charge-assisted seed mediated synthesis and application as surface-enhanced Raman scattering substrates

    NASA Astrophysics Data System (ADS)

    Yi, Zao; Luo, Jiangshan; Tan, Xiulan; Yi, Yong; Yao, Weitang; Kang, Xiaoli; Ye, Xin; Zhu, Wenkun; Duan, Tao; Yi, Yougen; Tang, Yongjian

    2015-11-01

    Mesoporous gold sponges were prepared using 4-dimethylaminopyridine (DMAP)-stabilized Au seeds. This is a general process, which involves a simple template-free method, room temperature reduction of HAuCl4·4H2O with hydroxylamine. The formation process of mesoporous gold sponges could be accounted for the electrostatic interaction (the small Au nanoparticles (~3 nm) and the positively charged DMAP-stabilized Au seeds) and Ostwald ripening process. The mesoporous gold sponges had appeared to undergo electrostatic adsorption initially, sequentially linear aggregation, welding and Ostwald ripening, then, they randomly cross link into self-supporting, three-dimensional networks with time. The mesoporous gold sponges exhibit higher surface area than the literature. In addition, application of the spongelike networks as an active material for surface-enhanced Raman scattering has been investigated by employing 4-aminothiophenol (4-ATP) molecules as a probe.

  1. Surfactant effects on alpha-factors in aeration systems.

    PubMed

    Rosso, Diego; Stenstrom, Michael K

    2006-04-01

    Aeration in wastewater treatment processes accounts for the largest fraction of plant energy costs. Aeration systems function by shearing the surface (surface aerators) or releasing bubbles at the bottom of the tank (coarse- or fine-bubble aerators). Surfactant accumulation on gas-liquid interfaces reduces mass transfer rates, and this reduction in general is larger for fine-bubble aerators. This study evaluates mass transfer effects on the characterization and specification of aeration systems in clean and process water conditions. Tests at different interfacial turbulence regimes show higher gas transfer depression for lower turbulence regimes. Contamination effects can be offset at the expense of operating efficiency, which is characteristic of surface aerators and coarse-bubble diffusers. Results describe the variability of alpha-factors measured at small scale, due to uncontrolled energy density. Results are also reported in dimensionless empirical correlations describing mass transfer as a function of physiochemical and geometrical characteristics of the aeration process.

  2. Processing of Lunar Soil Simulant for Space Exploration Applications

    NASA Technical Reports Server (NTRS)

    Sen, Subhayu; Ray, Chandra S.; Reddy, Ramana

    2005-01-01

    NASA's long-term vision for space exploration includes developing human habitats and conducting scientific investigations on planetary bodies, especially on Moon and Mars. To reduce the level of up-mass processing and utilization of planetary in-situ resources is recognized as an important element of this vision. Within this scope and context, we have undertaken a general effort aimed primarily at extracting and refining metals, developing glass, glass-ceramic, or traditional ceramic type materials using lunar soil simulants. In this paper we will present preliminary results on our effort on carbothermal reduction of oxides for elemental extraction and zone refining for obtaining high purity metals. In additions we will demonstrate the possibility of developing glasses from lunar soil simulant for fixing nuclear waste from potential nuclear power generators on planetary bodies. Compositional analysis, x-ray diffraction patterns and differential thermal analysis of processed samples will be presented.

  3. Mesoporous gold sponges: electric charge-assisted seed mediated synthesis and application as surface-enhanced Raman scattering substrates

    PubMed Central

    Yi, Zao; Luo, Jiangshan; Tan, Xiulan; Yi, Yong; Yao, Weitang; Kang, Xiaoli; Ye, Xin; Zhu, Wenkun; Duan, Tao; Yi, Yougen; Tang, Yongjian

    2015-01-01

    Mesoporous gold sponges were prepared using 4-dimethylaminopyridine (DMAP)-stabilized Au seeds. This is a general process, which involves a simple template-free method, room temperature reduction of HAuCl4·4H2O with hydroxylamine. The formation process of mesoporous gold sponges could be accounted for the electrostatic interaction (the small Au nanoparticles (~3 nm) and the positively charged DMAP-stabilized Au seeds) and Ostwald ripening process. The mesoporous gold sponges had appeared to undergo electrostatic adsorption initially, sequentially linear aggregation, welding and Ostwald ripening, then, they randomly cross link into self-supporting, three-dimensional networks with time. The mesoporous gold sponges exhibit higher surface area than the literature. In addition, application of the spongelike networks as an active material for surface-enhanced Raman scattering has been investigated by employing 4-aminothiophenol (4-ATP) molecules as a probe. PMID:26538365

  4. Testing of New Materials and Computer Aided Optimization of Process Parameters and Clamping Device During Predevelopment of Laser Welding Processes

    NASA Astrophysics Data System (ADS)

    Weidinger, Peter; Günther, Kay; Fitzel, Martin; Logvinov, Ruslan; Ilin, Alexander; Ploshikhin, Vasily; Hugger, Florian; Mann, Vincent; Roth, Stephan; Schmidt, Michael

    The necessity for weight reduction in motor vehicles in order to save fuel consumption pushes automotive suppliers to use materials of higher strength. Due to their excellent crash behavior high strength steels are increasingly applied in various structures. In this paper some predevelopment steps for a material change from a micro alloyed to dual phase and complex phase steels of a T-joint assembly are displayed. Initially the general weldability of the materials regarding pore formation, hardening in the heat affected zone and hot cracking susceptibility is discussed. After this basic investigation, the computer aided design optimization of a clamping device is shown, in which influences of the clamping jaw, the welding position and the clamping forces upon weld quality are presented. Finally experimental results of the welding process are displayed, which validate the numerical simulation.

  5. Substitution of saturated fat in processed meat products: a review.

    PubMed

    Ospina-E, J C; Sierra-C, A; Ochoa, O; Pérez-Álvarez, J A; Fernández-López, J

    2012-01-01

    The food industry is increasingly directing its efforts to produce and commercialize functional foods where the reduction or even elimination of saturated fat is an important goal. This situation arises from the concern of many institutions and individuals worldwide on the growth of non-transmissible diseases, particularly cardiovascular ones. This article presents a revision of the most important research carried out on processed meat products production and looks at the topic from two principal points of view: the nutritional and technological function of fat and the way in which it is gradually being replaced in the above-mentioned products. Many ingredients have been used to substitute fat but while the results concerning the nutritional composition of the final products are generally acceptable, the sensory aspects are not completely solved. This review emphasizes the use of plastic fats because they allow the highest fat substitution levels during its process and consumption without affecting the product behavior.

  6. Solar silicon via improved and expanded metallurgical silicon technology

    NASA Technical Reports Server (NTRS)

    Hunt, L. P.; Dosaj, V. D.; Mccormick, J. R.

    1977-01-01

    A completed preliminary survey of silica sources indicates that sufficient quantities of high-purity quartz are available in the U.S. and Canada to meet goals. Supply can easily meet demand for this little-sought commodity. Charcoal, as a reductant for silica, can be purified to a sufficient level by high-temperature fluorocarbon treatment and vacuum processing. High-temperature treatment causes partial graphitization which can lead to difficulty in smelting. Smelting of Arkansas quartz and purified charcoal produced kilogram quantities of silicon having impurity levels generally much lower than in MG-Si. Half of the goal was met of increasing the boron resistivity from 0.03 ohm-cm in metallurgical silicon to 0.3 ohm-cm in solar silicon. A cost analysis of the solidification process indicate $3.50-7.25/kg Si for the Czochralski-type process and $1.50-4.25/kg Si for the Bridgman-type technique.

  7. Whose fault is it? Fraud scandal in the milk industry and its impact on product image and consumption - The case of Brazil.

    PubMed

    Breitenbach, Raquel; Rodrigues, Heber; Brandão, Janaína Balk

    2018-06-01

    Food safety is a crucial thematic to any nation and the frauds in the food chain are an increasingly phenomena nowadays. The general goal of the present work was to identify the perception and behavior of Brazilian fresh milk consumers' in relation to the fraud in the milk production and sell chain. A total of 1015 consumers answered an online questionnaire on the variables that shape decision-making (individual differences, environmental influences and psychological stimuli or processes) and the behavior related to this decision process. The results were discussed based on the theoretical model proposed by Blackwell, Miniard, and Engel (2005) and their 7 stages. The results of this qualitative study showed that the impacts were declared, specially, in the reduction of milk consumption; losses to the image of the sector and the warming of the informal milk market, due to the increase in demand in this trade. The reduction of demand and the depreciation of the agents' image, have a negative impact on the entire chain, since it reduces revenues for all agents and, to a greater degree, for processors and related suppliers/farmers directly with the brands identified in the investigation actions and disclosed in the media. The female consumers were more affected, impacting on a greater reduction of the consumption. Unlike young consumers, they have not changed their behavior in relation to the chain. Copyright © 2018 Elsevier Ltd. All rights reserved.

  8. Medication Waste Reduction in Pediatric Pharmacy Batch Processes

    PubMed Central

    Veltri, Michael A.; Hamrock, Eric; Mollenkopf, Nicole L.; Holt, Kristen; Levin, Scott

    2014-01-01

    OBJECTIVES: To inform pediatric cart-fill batch scheduling for reductions in pharmaceutical waste using a case study and simulation analysis. METHODS: A pre and post intervention and simulation analysis was conducted during 3 months at a 205-bed children's center. An algorithm was developed to detect wasted medication based on time-stamped computerized provider order entry information. The algorithm was used to quantify pharmaceutical waste and associated costs for both preintervention (1 batch per day) and postintervention (3 batches per day) schedules. Further, simulation was used to systematically test 108 batch schedules outlining general characteristics that have an impact on the likelihood for waste. RESULTS: Switching from a 1-batch-per-day to a 3-batch-per-day schedule resulted in a 31.3% decrease in pharmaceutical waste (28.7% to 19.7%) and annual cost savings of $183,380. Simulation results demonstrate how increasing batch frequency facilitates a more just-in-time process that reduces waste. The most substantial gains are realized by shifting from a schedule of 1 batch per day to at least 2 batches per day. The simulation exhibits how waste reduction is also achievable by avoiding batch preparation during daily time periods where medication administration or medication discontinuations are frequent. Last, the simulation was used to show how reducing batch preparation time per batch provides some, albeit minimal, opportunity to decrease waste. CONCLUSIONS: The case study and simulation analysis demonstrate characteristics of batch scheduling that may support pediatric pharmacy managers in redesign toward minimizing pharmaceutical waste. PMID:25024671

  9. Medication waste reduction in pediatric pharmacy batch processes.

    PubMed

    Toerper, Matthew F; Veltri, Michael A; Hamrock, Eric; Mollenkopf, Nicole L; Holt, Kristen; Levin, Scott

    2014-04-01

    To inform pediatric cart-fill batch scheduling for reductions in pharmaceutical waste using a case study and simulation analysis. A pre and post intervention and simulation analysis was conducted during 3 months at a 205-bed children's center. An algorithm was developed to detect wasted medication based on time-stamped computerized provider order entry information. The algorithm was used to quantify pharmaceutical waste and associated costs for both preintervention (1 batch per day) and postintervention (3 batches per day) schedules. Further, simulation was used to systematically test 108 batch schedules outlining general characteristics that have an impact on the likelihood for waste. Switching from a 1-batch-per-day to a 3-batch-per-day schedule resulted in a 31.3% decrease in pharmaceutical waste (28.7% to 19.7%) and annual cost savings of $183,380. Simulation results demonstrate how increasing batch frequency facilitates a more just-in-time process that reduces waste. The most substantial gains are realized by shifting from a schedule of 1 batch per day to at least 2 batches per day. The simulation exhibits how waste reduction is also achievable by avoiding batch preparation during daily time periods where medication administration or medication discontinuations are frequent. Last, the simulation was used to show how reducing batch preparation time per batch provides some, albeit minimal, opportunity to decrease waste. The case study and simulation analysis demonstrate characteristics of batch scheduling that may support pediatric pharmacy managers in redesign toward minimizing pharmaceutical waste.

  10. Facilitation of information processing in the primary somatosensory area in the ball rotation task.

    PubMed

    Wasaka, Toshiaki; Kida, Tetsuo; Kakigi, Ryusuke

    2017-11-14

    Somatosensory input to the brain is known to be modulated during voluntary movement. It has been demonstrated that the response in the primary somatosensory cortex (SI) is generally gated during simple movement of the corresponding body part. This study investigated sensorimotor integration in the SI during manual movement using a motor task combining movement complexity and object manipulation. While the amplitude of M20 and M30 generated in the SI showed a significant reduction during manual movement, the subsequent component (M38) was significantly higher in the motor task than in the stationary condition. Especially, that in the ball rotation task showed a significant enhancement compared with those in the ball grasping and stone and paper tasks. Although sensorimotor integration in the SI generally has an inhibitory effect on information processing, here we found facilitation. Since the ball rotation task seems to be increasing the demand for somatosensory information to control the complex movements and operate two balls in the palm, it may have resulted in an enhancement of M38 generated in the SI.

  11. Lactobacillus acidophilus—Rutin Interplay Investigated by Proteomics

    PubMed Central

    Mazzeo, Maria Fiorella; Lippolis, Rosa; Sorrentino, Alida; Liberti, Sarah; Fragnito, Federica; Siciliano, Rosa Anna

    2015-01-01

    Dietary polyphenols are bioactive molecules that beneficially affect human health, due to their anti-oxidant, anti-inflammatory, cardio-protective and chemopreventive properties. They are absorbed in a very low percentage in the small intestine and reach intact the colon, where they are metabolized by the gut microbiota. Although it is well documented a key role of microbial metabolism in the absorption of polyphenols and modulation of their biological activity, molecular mechanisms at the basis of the bacteria-polyphenols interplay are still poorly understood. In this context, differential proteomics was applied to reveal adaptive response mechanisms that enabled a potential probiotic Lactobacillus acidophilus strain to survive in the presence of the dietary polyphenol rutin. The response to rutin mainly modulated the expression level of proteins involved in general stress response mechanisms and, in particular, induced the activation of protein quality control systems, and affected carbohydrate and amino acid metabolism, protein synthesis and cell wall integrity. Moreover, rutin triggered the expression of proteins involved in oxidation-reduction processes.This study provides a first general view of the impact of dietary polyphenols on metabolic and biological processes of L. acidophilus. PMID:26544973

  12. Lactobacillus acidophilus-Rutin Interplay Investigated by Proteomics.

    PubMed

    Mazzeo, Maria Fiorella; Lippolis, Rosa; Sorrentino, Alida; Liberti, Sarah; Fragnito, Federica; Siciliano, Rosa Anna

    2015-01-01

    Dietary polyphenols are bioactive molecules that beneficially affect human health, due to their anti-oxidant, anti-inflammatory, cardio-protective and chemopreventive properties. They are absorbed in a very low percentage in the small intestine and reach intact the colon, where they are metabolized by the gut microbiota. Although it is well documented a key role of microbial metabolism in the absorption of polyphenols and modulation of their biological activity, molecular mechanisms at the basis of the bacteria-polyphenols interplay are still poorly understood. In this context, differential proteomics was applied to reveal adaptive response mechanisms that enabled a potential probiotic Lactobacillus acidophilus strain to survive in the presence of the dietary polyphenol rutin. The response to rutin mainly modulated the expression level of proteins involved in general stress response mechanisms and, in particular, induced the activation of protein quality control systems, and affected carbohydrate and amino acid metabolism, protein synthesis and cell wall integrity. Moreover, rutin triggered the expression of proteins involved in oxidation-reduction processes.This study provides a first general view of the impact of dietary polyphenols on metabolic and biological processes of L. acidophilus.

  13. Use of the national surgical quality improvement program to reduce surgical mortality: implementation of intensive preoperative screening and intervention.

    PubMed

    Konstantinidis, Agathoklis; Fogel, Sandy; Jones, James; Gilliam, Brenda; Kundzins, John; Baker, Christopher

    2014-09-01

    The American College of Surgeons National Surgical Quality Improvement Program (NSQIP) data at our institution indicated that surgical mortality was significantly higher than expected. This study examines the effect of implementation of a strict, intensive preoperative screening and intervention process on postoperative mortality at our institution, as measured by the NSQIP. Carilion Roanoke Memorial Hospital (CRMH) is a 763-bed tertiary care hospital serving a population of one million people in southwest Virginia. Data were collected for NSQIP at CRMH from July 2007 to December 2012. In January 2010, a new preoperative process was implemented to include risk assessment and intervention for hypertension, cardiac disease, pulmonary disease, diabetes, renal disease, and obstructive sleep apnea. Before initiation of our preoperative program (July 2007 to January 2010), odds ratios (ORs) for 30-day mortality in general and vascular cases were significantly higher than expected (1.40, 1.43, 1.58, and 1.56 in successive reporting periods). Beginning with the first report after implementation of the preoperative screening program, CRMH showed a progressively decreasing OR for overall 30-day mortality (1.26, 1.19, 1.14, 0.86, 0.82, 0.84, 0.89) with similar reductions in both general (0.92) and vascular (0.92) surgery. The implementation of an intensive preoperative screening and intervention process in our institution was accompanied by a significant decrease in the 30-day mortality for general surgery and vascular procedures, as measured by the NSQIP.

  14. Oxygen and superoxide-mediated redox kinetics of iron complexed by humic substances in coastal seawater.

    PubMed

    Fujii, Manabu; Rose, Andrew L; Waite, T David; Omura, Tatsuo

    2010-12-15

    Complexes with terrestrially derived humic substances represent one of the most reactive pools of dissolved Fe in natural waters. In this work, redox kinetics of Fe-humic substance complexes (FeL) in simulated coastal seawater were investigated using chemiluminescence techniques with particular attention given to interactions with dioxygen (O2) and superoxide (O2•-). Although rate constants of FeIIL oxidation by O2 (5.6-52 M-1 · s-1) were 4-5 orders of magnitude less than those for O2•- (6.9-23 × 105 M-1 · s-1),O2 is likely to outcompete O2•- for FeIIL oxidation in coastal seawaters where steady-state O2•- concentrations are generally subnanomolar. Rate constants for FeIIIL reduction by O2•- of 1.8-5.6 × 104 M-1 · s-1 were also determined. From the balance of FeIIL oxidation rates and O2•- -mediated FeIIIL reduction rates, steady-state FeIIL concentrations were estimated to be in the subpicomolar to picomolar range, which is generally lower than measured in situ Fe(II) concentrations under relevant conditions. This suggests that (i) processes other than O2•- -mediated reduction (such as photochemical ligand-to-metal charge transfer) may be responsible for Fe(II) formation, (ii) the in situ ligands differ significantly from the humic substances used in this work, and/ or (iii) the influence of other environmental factors such as pH and temperature on Fe redox kinetics may have to be considered.

  15. Prevalence of β-lactamase genes in domestic washing machines and dishwashers and the impact of laundering processes on antibiotic-resistant bacteria.

    PubMed

    Rehberg, L; Frontzek, A; Melhus, Å; Bockmühl, D P

    2017-12-01

    To investigate the prevalence of β-lactamase genes in domestic washing machines and dishwashers, and the decontamination efficacy of laundering. For the first investigation, swab samples from washing machines (n = 29) and dishwashers (n = 24) were analysed by real-time quantitative PCR to detect genes encoding β-lactamases. To test the impact of laundering on resistant bacteria, cotton test swatches were artificially contaminated with susceptible and resistant strains of Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus within a second investigation. They were washed in a domestic washing machine with or without activated oxygen bleach (AOB)-containing detergent at 20-50°C. β-Lactamase genes (most commonly of the AmpC- and OXA-type) were detected in 79% of the washing machines and in 96% of the dishwashers and Pseudomonadaceae dominated the microbiota. The level of bacterial reduction after laundering was ≥80% for all Ps. aeruginosa and Kl. pneumoniae strains, while it was only 37-61% for the methicillin-resistant Staph. aureus outbreak strain. In general, the reduction was tendentially higher for susceptible bacteria than for the resistant outbreak strains, especially for Staph. aureus. β-Lactamase genes seem to be frequently present in domestic appliances and may pose a potential risk for cross-contamination and horizontal transfer of genes encoding resistance against clinically important β-lactams. In general, higher temperatures and the use of AOB can improve the reduction of antibiotic-resistant bacteria, including Staph. aureus which appears to be less susceptible to the decontamination effect of laundering. Data on the presence of antibiotic-resistant bacteria in the domestic environment are limited. This study suggests that β-lactamase genes in washing machines and dishwashers are frequent, and that antibiotic-resistant strains are generally more resistant to the used washing conditions. © 2017 The Society for Applied Microbiology.

  16. Kinetics and mechanisms of 1,5-dihydroflavin reduction of carbonyl compounds and flavin oxidation of alcohols. III. Oxidation of benzoin by flavin and reduction of benzil by 1,5-dihydroflavin

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bruice, T.C.; Taulane, J.P.

    1976-11-24

    The oxidation of benzoin by lumiflavin-3-acetic acid (Fl/sub ox/) to provide benzil and 1,5-dihydrolumiflavin-3-acetic acid (FlH/sub 2/) is a readily reversible reaction. It has been established that the mechanism involves general base ionization of benzoin carbon acid (..cap alpha..-ketol) to yield endiolate anion, followed by partitioning of the endiolate anion back to benzoin through general acid proton donation and to benzil by reaction with Fl/sub ox/. The reaction of endiolate anion with Fl/sub ox/ is not subject to acid or base catalysis. Evidence that ionization of benzoin precedes its oxidation by Fl/sub ox/ stems from the observation that the ratemore » attributed to the latter process possesses a constant equal to that for racemization of (+)-benzoin and O/sub 2/ oxidation of benzoin and that this rate constant is characterized by a primary deuterium kinetic isotope effect (k/sup benzoin//k/sup ..cap alpha..-/sup 2/H-benzoin/) of 7.24 +- 1.5. Reduction of benzil to benzoin by FlH/sub 2/ is pH and buffer insensitive below the pK/sub a/ of FlH/sub 2/. These results are consistent with either general acid catalyzed attack of benzoin carbanion at the 4a-position of Fl/sub ox/, followed by a specific base catalyzed collapse of adduct to diketone and dihydroflavin (Scheme III), or to the uncatalyzed reaction of carbanion (endiolate anion) with flavin to provide a semidione-flavin radical pair which then goes on to diketone and dihydroflavin in a non-acid-base catalyzed reaction (Scheme V). These mechanisms are discussed in terms of the kinetics of reaction of other carbanion species with flavin.« less

  17. Sadness and susceptibility to judgmental bias: the case of anchoring.

    PubMed

    Bodenhausen, G V; Gabriel, S; Lineberger, M

    2000-07-01

    In a wide range of empirical paradigms, sadness has been associated with more extensive and detail-oriented thinking than happiness, resulting in reductions in judgmental bias that arise from reliance on stereotypes and other simple decision heuristics. It was hypothesized that anchoring would constitute a significant exception to this general pattern. Recent research on anchoring indicates that an active thought process underlies the emergence of this bias. If sad people are likely to think more actively about the judgmental anchor than their neutral-mood counterparts, their subsequent judgments should be more likely to be assimilated toward this reference point. This prediction was confirmed in two experiments demonstrating that sad people are indeed more susceptible to anchoring bias than are people in a neutral mood. Moreover, this effect generalized over judgments in positive, neutral, and negative content domains.

  18. [Thymus surgery in a general surgery department].

    PubMed

    Mega, Raquel; Coelho, Fátima; Pimentel, Teresa; Ribero, Rui; Matos, Novo de; Araújo, António

    2005-01-01

    Evaluation of thymectomy cases between 1990-2003, in a General Surgery Department. Evaluation of the therapeutic efficacy in Miastenia Gravis patients. Retrospective study based on evaluation of data from Serviço de Cirurgia, Neurologia and Consult de Neurology processes, between 1990-2003, of 15 patients submitted to total thymectomy. 15 patients, aged 17 to 72, 11 female and 4 male. Miastenia Gravis was the main indication for surgery, for uncontrollable symptoms or suspicion of thymoma. In patients with myasthenia, surgery was accomplish after compensation of symptoms. There weren't post-surgery complications. Pathology were divided in thymic hyperplasia and thymoma. Miastenia patients have there symptoms diminished or stable with reduction or cessation of medical therapy. Miastenia was the most frequent indication for thymectomy. Surgery was good results, with low morbimortality, as long as the protocols are respected.

  19. Evidence of phase nucleation during olivine diffusion creep: a new perspective for mantle strain localisation

    NASA Astrophysics Data System (ADS)

    Précigout, Jacques; Stünitz, Holger

    2017-04-01

    Mantle strain localisation is of great importance for lithosphere dynamics, but the cause for this phenomenon remains very elusive, particularly in conditions of the strong and ductile uppermost mantle. In these latter, grain size reduction leading to diffusion creep in olivine is believed to be one of the best candidates to account for strain localisation. However, the mechanisms of grain size reduction in this regime are still poorly understood. Here we show the results of Griggs-type experiments that document grain size reduction and material weakening during wet olivine diffusion creep at 900 °C and 1.2 GPa. While occurring for both, mono-phase and two-phase aggregates, grain size reduction is coeval with strain localisation and local phase mixing in olivine-pyroxene aggregates. Based on evidence of fluid inclusions and cracks filled with a fine-grained phase mixture, we conclude that grain size reduces as a result of fluid-assisted nucleation. Cavitation induced by grain boundary sliding (creep cavitation) can be inferred, and may play a critical role for olivine grain size reduction. Amongst their implications for rock rheology in general, our findings highlight a key process for strain localisation in the ductile uppermost mantle. This study has been published under the reference: "Précigout, J., and Stünitz, H. (2016) Evidence of phase nucleation during olivine diffusion creep: a new perspective for mantle strain localisation. Earth and Planetary Science Letters 455: 94-105, doi:101016/j.epsl.2016.09.029".

  20. Reduction of jarosite by Shewanella oneidensis MR-1 and secondary mineralization

    NASA Astrophysics Data System (ADS)

    Bingjie, Ouyang; Xiancai, Lu; Huan, Liu; Juan, Li; Tingting, Zhu; Xiangyu, Zhu; Jianjun, Lu; Rucheng, Wang

    2014-01-01

    Jarosite is a common mineral in a variety of environments formed by the oxidation of iron sulfide normally accompanying with the generation of acid mine drainage (AMD) in mining areas or acid rock drainages (ARD) in many localities. Decomposition of jarosite by dissimilatory iron reducing bacteria (DIRB) influences the mobility of many heavy metals generally accommodated in natural jarosite. This study examined the anaerobic reduction of synthesized jarosite by Shewanella oneidensis strain MR-1, a typical facultative bacteria. The release of ferrous and ferric ion, as well as sulfate and potassium, in the inoculated experimental group lasting 80 days is much higher than that in abiotic control groups. The detection of bicarbonate and acetate in experimental solution further confirms the mechanism of microbial reduction of jarosite, in which lactate acts as the electron donor. The produced ferrous iron stimulates the subsequent secondary mineralization, leading to precipitation and transformation of various iron-containing minerals. Green rust and goethite are the intermediate minerals of the microbial reduction process under anoxic conditions, and the end products include magnetite and siderite. In aerobic environments, goethite, magnetite and siderite were also detected, but the contents were relatively lower. While in abiotic experiments, only goethite has been detected as a product. Thus, the microbial reduction and subsequent mineral transformation can remarkably influence the geochemical cycling of iron and sulfur in supergene environments, as well as the mobility of heavy metals commonly accommodated in jarosite.

  1. Just-in-time adaptive classifiers-part II: designing the classifier.

    PubMed

    Alippi, Cesare; Roveri, Manuel

    2008-12-01

    Aging effects, environmental changes, thermal drifts, and soft and hard faults affect physical systems by changing their nature and behavior over time. To cope with a process evolution adaptive solutions must be envisaged to track its dynamics; in this direction, adaptive classifiers are generally designed by assuming the stationary hypothesis for the process generating the data with very few results addressing nonstationary environments. This paper proposes a methodology based on k-nearest neighbor (NN) classifiers for designing adaptive classification systems able to react to changing conditions just-in-time (JIT), i.e., exactly when it is needed. k-NN classifiers have been selected for their computational-free training phase, the possibility to easily estimate the model complexity k and keep under control the computational complexity of the classifier through suitable data reduction mechanisms. A JIT classifier requires a temporal detection of a (possible) process deviation (aspect tackled in a companion paper) followed by an adaptive management of the knowledge base (KB) of the classifier to cope with the process change. The novelty of the proposed approach resides in the general framework supporting the real-time update of the KB of the classification system in response to novel information coming from the process both in stationary conditions (accuracy improvement) and in nonstationary ones (process tracking) and in providing a suitable estimate of k. It is shown that the classification system grants consistency once the change targets the process generating the data in a new stationary state, as it is the case in many real applications.

  2. Reuse of process water in a waste-to-energy plant: An Italian case of study.

    PubMed

    Gardoni, Davide; Catenacci, Arianna; Antonelli, Manuela

    2015-09-01

    The minimisation of water consumption in waste-to-energy (WtE) plants is an outstanding issue, especially in those regions where water supply is critical and withdrawals come from municipal waterworks. Among the various possible solutions, the most general, simple and effective one is the reuse of process water. This paper discusses the effectiveness of two different reuse options in an Italian WtE plant, starting from the analytical characterisation and the flow-rate measurement of fresh water and process water flows derived from each utility internal to the WtE plant (e.g. cooling, bottom ash quenching, flue gas wet scrubbing). This census allowed identifying the possible direct connections that optimise the reuse scheme, avoiding additional water treatments. The effluent of the physical-chemical wastewater treatment plant (WWTP), located in the WtE plant, was considered not adequate to be directly reused because of the possible deposition of mineral salts and clogging potential associated to residual suspended solids. Nevertheless, to obtain high reduction in water consumption, reverse osmosis should be installed to remove non-metallic ions (Cl(-), SO4(2-)) and residual organic and inorganic pollutants. Two efficient solutions were identified. The first, a simple reuse scheme based on a cascade configuration, allowed 45% reduction in water consumption (from 1.81 to 0.99m(3)tMSW(-1), MSW: Municipal Solid Waste) without specific water treatments. The second solution, a cascade configuration with a recycle based on a reverse osmosis process, allowed 74% reduction in water consumption (from 1.81 to 0.46m(3)tMSW(-1)). The results of the present work show that it is possible to reduce the water consumption, and in turn the wastewater production, reducing at the same time the operating cost of the WtE plant. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Salmonella Inactivation During Extrusion of an Oat Flour Model Food.

    PubMed

    Anderson, Nathan M; Keller, Susanne E; Mishra, Niharika; Pickens, Shannon; Gradl, Dana; Hartter, Tim; Rokey, Galen; Dohl, Christopher; Plattner, Brian; Chirtel, Stuart; Grasso-Kelley, Elizabeth M

    2017-03-01

    Little research exists on Salmonella inactivation during extrusion processing, yet many outbreaks associated with low water activity foods since 2006 were linked to extruded foods. The aim of this research was to study Salmonella inactivation during extrusion of a model cereal product. Oat flour was inoculated with Salmonella enterica serovar Agona, an outbreak strain isolated from puffed cereals, and processed using a single-screw extruder at a feed rate of 75 kg/h and a screw speed of 500 rpm. Extrudate samples were collected from the barrel outlet in sterile bags and immediately cooled in an ice-water bath. Populations were determined using standard plate count methods or a modified most probable number when populations were low. Reductions in population were determined and analyzed using a general linear model. The regression model obtained for the response surface tested was Log (N R /N O ) = 20.50 + 0.82T - 141.16a w - 0.0039T 2 + 87.91a w 2 (R 2 = 0.69). The model showed significant (p < 0.05) linear and quadratic effects of a w and temperature and enabled an assessment of critical control parameters. Reductions of 0.67 ± 0.14 to 7.34 ± 0.02 log CFU/g were observed over ranges of a w (0.72 to 0.96) and temperature (65 to 100 °C) tested. Processing conditions above 82 °C and 0.89 a w achieved on average greater than a 5-log reduction of Salmonella. Results indicate that extrusion is an effective means for reducing Salmonella as most processes commonly employed to produce cereals and other low water activity foods exceed these parameters. Thus, contamination of an extruded food product would most likely occur postprocessing as a result of environmental contamination or through the addition of coatings and flavorings. © 2017 Institute of Food Technologists®.

  4. Reduction of Chlorate by Iron Mediated Processes: Implications for Oxy-Chlorine Species on Mars and Earth

    NASA Astrophysics Data System (ADS)

    Brundrett, M.; Yan, W.; Jackson, W. A.

    2017-12-01

    Studies have confirmed the presence of chlorate (ClO3-) and perchlorate (ClO4-) in terrestrial systems, lunar regolith, Martian surface soils, and meteorites [1, 2, 4]. A roughly equimolar ratio of ClO3- : ClO4- has been observed for most systems with the only major exceptions the Antarctica dry valley soils (MDV) and Martian surface material, where the ClO3- : ClO4- ratios are significantly less than 1 [3, 4]. All known ClO4- production mechanisms produce molar ratios of ClO3-: ClO4- equal to or greater than 1 [5]. Post depositional processes may explain the potential reduction of ClO3-. The objective of this study was to determine the potential abiotic transformation of ClO3- by Fe (II)-bearing minerals, similar to known reactions between NO3- and Fe (II) minerals. The presence of iron-derived minerals has been established in the MDV, Martian soils, and chondrite meteorites. Batch experiments were conducted by reacting four Fe (II)-bearing minerals (wustite, siderite, magnetite, and green rust) with ClO3- at various pH (4.5, 6.5, 8.9). Chlorate reduction was rapid (half-life on the order of hours to days) and generally ClO3- was quantitatively converted to Cl-. Results of this study will increase our understanding of surface reactions that produced and transformed oxy-chlorine compounds on Mars elucidating past and present Martian surface conditions. The study also has implications into the understanding of the evolutionary processes that previously or currently dictate the abiotic geochemical processing of oxy-chlorine anions through terrestrial systems. [1] Jackson et al. (2015) EPSL 430, 470-476. [2] Rao et al. (2010) ES&T 44, 8429-8434. [3] Jackson et al. (2010) ES&T 44, 4869-4876. [4] Hecht et al. (2009) SCI 325, 64-67. [5] Rao et al. (2010) ES&T 44, 2961-2967.

  5. POCS-based reconstruction of multiplexed sensitivity encoded MRI (POCSMUSE): a general algorithm for reducing motion-related artifacts

    PubMed Central

    Chu, Mei-Lan; Chang, Hing-Chiu; Chung, Hsiao-Wen; Truong, Trong-Kha; Bashir, Mustafa R.; Chen, Nan-kuei

    2014-01-01

    Purpose A projection onto convex sets reconstruction of multiplexed sensitivity encoded MRI (POCSMUSE) is developed to reduce motion-related artifacts, including respiration artifacts in abdominal imaging and aliasing artifacts in interleaved diffusion weighted imaging (DWI). Theory Images with reduced artifacts are reconstructed with an iterative POCS procedure that uses the coil sensitivity profile as a constraint. This method can be applied to data obtained with different pulse sequences and k-space trajectories. In addition, various constraints can be incorporated to stabilize the reconstruction of ill-conditioned matrices. Methods The POCSMUSE technique was applied to abdominal fast spin-echo imaging data, and its effectiveness in respiratory-triggered scans was evaluated. The POCSMUSE method was also applied to reduce aliasing artifacts due to shot-to-shot phase variations in interleaved DWI data corresponding to different k-space trajectories and matrix condition numbers. Results Experimental results show that the POCSMUSE technique can effectively reduce motion-related artifacts in data obtained with different pulse sequences, k-space trajectories and contrasts. Conclusion POCSMUSE is a general post-processing algorithm for reduction of motion-related artifacts. It is compatible with different pulse sequences, and can also be used to further reduce residual artifacts in data produced by existing motion artifact reduction methods. PMID:25394325

  6. Participatory and Collaborative Digital Mapping to Enhance Disaster Resilience

    NASA Astrophysics Data System (ADS)

    Liu, Wei; Dugar, Sumit; McCallum, Ian; Brown, Sarah; See, Linda; Mechler, Reinhard

    2017-04-01

    Critical knowledge gaps seriously hinder disaster risk reduction and resilience building efforts, especially in disaster prone least developing countries. The information scarcity is highest at local levels, in terms of the spatial information of risk, resources and capacities of communities. We propose a general procedure that combines community-based participatory mapping processes, which has been widely used by in various government and non-government organization projects in the fields of natural resources management, disaster risk reduction and rural development, and the emerging collaborative digital mapping techniques to tackle this challenge. We demonstrate the value and potential of this general participatory and collaborative digital mapping by conducting a pilot study in the flood prone lower Karnali River basin in Western Nepal. We engaged a range of stakeholders to generate geographic information on resources, capacities and flood risks of pilot communities according to local needs. The new digital community maps are richer in contents, more accurate, and easier to update and share than those produced using conventional Vulnerability and Capacity Assessments (VCAs), a variant of Participatory Rural Appraisal (PRA) that is widely used by in various government and non-government organizations. This approach, as an inclusive form of risk knowledge co-generation, can play a critical role in improving evidence-based understanding of disaster risk and enhance disaster resilience worldwide.

  7. Tinning/Trimming Robot System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fureigh, M.L.

    In a new surface mount assembly area at AlliedSignal Inc., Kansas City Division (KCD), a tinning/trimming robot system tins and trims the gold-plated leads of surface mount technology (SMT) transistors. The KCD-designed system uses a Unimation PUMA 260 robot, a General Production Devices SP-2000 solder pot; water-soluble Blackstone No. 2508 flux; and a Virtual Industries high-temperature, ESD-conductive, miniature suction cup. After the manual cleaning operation, the processed SMT transistors go to the QUADSTAR Automated Component Placement System for a Radar Logic Assembly. The benefits are reductions in the cost of nonconformance, worker fatigue, and standard hours.

  8. The optimal number of menu options per panel

    NASA Technical Reports Server (NTRS)

    Paap, Kenneth R.; Roske-Hofstrand, Renate J.

    1986-01-01

    An evaluation is made of the effects of the 'funneling' phenomenon, in an analysis of hierarchical menu structures' optimal search times which builds on the work of Lee and MacGregor (1985). Funneling is a reduction in the total number of options processed through the design of a system of greater choice 'depth' and correspondingly restricted choice 'breadth'. Both random and ordered menus are treated. The available evidence is found to support the general conclusion that randomly ordered menu panels should have only a few (4-8) options, while organized menus should contain as many options as 64.

  9. Medi-Cal Hospital Contracting—Did It Achieve Its Legislative Objectives?

    PubMed Central

    Brown, E. Richard; Price, Walter T.; Cousineau, Michael R.

    1985-01-01

    The 1982 Medi-Cal reforms and reductions established selective contracting with hospitals for inpatient care of Medi-Cal beneficiaries. The legislation established a special negotiator and criteria to be used in selecting contract hospitals. We report the findings of a study that analyzed the characteristics of contract and noncontract hospitals in Los Angeles County to assess how well these criteria were reflected in the outcome of the contracting process. We examine issues of beneficiary access to general inpatient care and to specialized services, the efficiency of contract hospitals compared with noncontract ones and quality-related issues. PMID:3898595

  10. 38 CFR 36.4223 - Interest rate reduction refinancing loan.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Interest rate reduction..., Including Site Preparation General Provisions § 36.4223 Interest rate reduction refinancing loan. (a) A... to reduce the interest rate payable on the Department of Veterans Affairs loan provided the following...

  11. Stimulus Equalization: Temporary Reduction of Stimulus Complexity to Facilitate Discrimination Learning.

    ERIC Educational Resources Information Center

    Hoko, J. Aaron; LeBlanc, Judith M.

    1988-01-01

    Because disabled learners may profit from procedures using gradual stimulus change, this study utilized a microcomputer to investigate the effectiveness of stimulus equalization, an error reduction procedure involving an abrupt but temporary reduction of dimensional complexity. The procedure was found to be generally effective and implications for…

  12. 48 CFR 904.402 - General.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Safety and Health” provide for reductions of fee or profit that is earned by the contractor depending... include a clause that provides for an appropriate reduction in the fees or amounts paid to the contractor... degrees of violations and the amount of the reduction attributable to each degree of violation. The clause...

  13. 48 CFR 904.402 - General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Safety and Health” provide for reductions of fee or profit that is earned by the contractor depending... include a clause that provides for an appropriate reduction in the fees or amounts paid to the contractor... degrees of violations and the amount of the reduction attributable to each degree of violation. The clause...

  14. 20 CFR 229.51 - Adjustment of age reduction.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false Adjustment of age reduction. 229.51 Section... age reduction. (a) General. If an age reduced employee or spouse overall minimum benefit is not paid for certain months before the employee or spouse attains retirement age, or the employee becomes...

  15. 20 CFR 229.51 - Adjustment of age reduction.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true Adjustment of age reduction. 229.51 Section... age reduction. (a) General. If an age reduced employee or spouse overall minimum benefit is not paid for certain months before the employee or spouse attains retirement age, or the employee becomes...

  16. 20 CFR 229.51 - Adjustment of age reduction.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true Adjustment of age reduction. 229.51 Section... age reduction. (a) General. If an age reduced employee or spouse overall minimum benefit is not paid for certain months before the employee or spouse attains retirement age, or the employee becomes...

  17. 20 CFR 229.51 - Adjustment of age reduction.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false Adjustment of age reduction. 229.51 Section... age reduction. (a) General. If an age reduced employee or spouse overall minimum benefit is not paid for certain months before the employee or spouse attains retirement age, or the employee becomes...

  18. 20 CFR 229.51 - Adjustment of age reduction.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Adjustment of age reduction. 229.51 Section... age reduction. (a) General. If an age reduced employee or spouse overall minimum benefit is not paid for certain months before the employee or spouse attains retirement age, or the employee becomes...

  19. 20 CFR 227.4 - Reduction for employer pension.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Reduction for employer pension. 227.4 Section... COMPUTING SUPPLEMENTAL ANNUITIES § 227.4 Reduction for employer pension. (a) General. The supplemental annuity for each month is reduced by the amount of any private pension the employee is receiving for that...

  20. A fast efficient implicit scheme for the gasdynamic equations using a matrix reduction technique

    NASA Technical Reports Server (NTRS)

    Barth, T. J.; Steger, J. L.

    1985-01-01

    An efficient implicit finite-difference algorithm for the gasdynamic equations utilizing matrix reduction techniques is presented. A significant reduction in arithmetic operations is achieved without loss of the stability characteristics generality found in the Beam and Warming approximate factorization algorithm. Steady-state solutions to the conservative Euler equations in generalized coordinates are obtained for transonic flows and used to show that the method offers computational advantages over the conventional Beam and Warming scheme. Existing Beam and Warming codes can be retrofit with minimal effort. The theoretical extension of the matrix reduction technique to the full Navier-Stokes equations in Cartesian coordinates is presented in detail. Linear stability, using a Fourier stability analysis, is demonstrated and discussed for the one-dimensional Euler equations.

  1. The Effect of Carbonaceous Reductant Selection on Chromite Pre-reduction

    NASA Astrophysics Data System (ADS)

    Kleynhans, E. L. J.; Beukes, J. P.; Van Zyl, P. G.; Bunt, J. R.; Nkosi, N. S. B.; Venter, M.

    2017-04-01

    Ferrochrome (FeCr) production is an energy-intensive process. Currently, the pelletized chromite pre-reduction process, also referred to as solid-state reduction of chromite, is most likely the FeCr production process with the lowest specific electricity consumption, i.e., MWh/t FeCr produced. In this study, the effects of carbonaceous reductant selection on chromite pre-reduction and cured pellet strength were investigated. Multiple linear regression analysis was employed to evaluate the effect of reductant characteristics on the aforementioned two parameters. This yielded mathematical solutions that can be used by FeCr producers to select reductants more optimally in future. Additionally, the results indicated that hydrogen (H)- (24 pct) and volatile content (45.8 pct) were the most significant contributors for predicting variance in pre-reduction and compressive strength, respectively. The role of H within this context is postulated to be linked to the ability of a reductant to release H that can induce reduction. Therefore, contrary to the current operational selection criteria, the authors believe that thermally untreated reductants ( e.g., anthracite, as opposed to coke or char), with volatile contents close to the currently applied specification (to ensure pellet strength), would be optimal, since it would maximize H content that would enhance pre-reduction.

  2. Study on the syhthesis process of tetracaine hydrochloride

    NASA Astrophysics Data System (ADS)

    Li, Wenli; Zhao, Jie; Cui, Yujie

    2017-05-01

    Tetrachloride hydrochloride is a local anesthetic with long-acting ester, and it is usually present in the form of a hydrochloride salt. Firsleb first synthesized the tetracaine by experiment in 1928, which is one of the recognized clinical potent anesthetics. This medicine has the advantages of stable physical and chemical properties, the rapid role and long maintenance. Tetracaine is also used for ophthalmic surface anesthesia as one of the main local anesthetic just like conduction block anesthesia, mucosal surface anesthesia and epidural anesthesia. So far, the research mainly engaged in its clinical application research, and the research strength is relatively small in the field of synthetic technology. The general cost of the existing production process is high, and the yield is low. In addition, the reaction time is long and the reaction conditions are harsh. In this paper, a new synthetic method was proposed for the synthesis of tetracaine hydrochloride. The reaction route has the advantages of few steps, high yield, short reaction time and mild reaction conditions. The cheap p-nitrobenzoic acid was selected as raw material. By esterification with ethanol and reaction with n-butyraldehyde (the reaction process includes nitro reduction, aldol condensation and hydrogenation reduction), the intermediate was transesterified with dimethylaminoethanol under basic conditions. Finally, the PH value was adjusted in the ethanol solvent. After experiencing 4 steps reaction, the crude tetracaine hydrochloride was obtained.

  3. Drugs at the campsite: Socio-spatial relations and drug use at music festivals.

    PubMed

    Dilkes-Frayne, Ella

    2016-07-01

    Music festivals have received relatively little research attention despite being key sites for alcohol and drug use among young people internationally. Research into music festivals and the social contexts of drug use more generally, has tended to focus on social and cultural processes without sufficient regard for the mediating role of space and spatial processes. Adopting a relational approach to space and the social, from Actor-Network Theory and human geography, I examine how socio-spatial relations are generated in campsites at multiple-day music festivals. The data are drawn from ethnographic observations at music festivals around Melbourne, Australia; interviews with 18-23 year olds; and participant-written diaries. Through the analysis, the campsite is revealed as a space in process, the making of which is bound up in how drug use unfolds. Campsite relations mediate the formation of drug knowledge and norms, informal harm reduction practices, access to and exchange of drugs, and rest and recovery following drug use. Greater attendance to socio-spatial relations affords new insights regarding how festival spaces and their social effects are generated, and how they give rise to particular drug use practices. These findings also point to how festival harm reduction strategies might be enhanced through the promotion of enabling socio-spatial relations. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. Extent and persistence of secondary water quality impacts after enhanced reductive bioremediation

    USGS Publications Warehouse

    Borden, Robert C.; Jason M. Tillotson,; Ng, Gene-Hua Crystal.; Bekins, Barbara A.; Kent, Douglas B.; Curtis, Gary P.

    2017-01-01

    Electron donor (ED) addition can be very effective in stimulating enhanced reductive bioremediation (ERB) of a wide variety of groundwater contaminants. However, ERB can result in Secondary Water Quality Impacts (SWQIs) including decreased levels of dissolved oxygen (O2), nitrate (NO3- ), and sulfate (SO42- ), and elevated levels of dissolved manganese (Mn2+), dissolved iron (Fe2+), methane (CH4), sulfide (S2- ), organic carbon, and naturally occurring hazardous compounds (e.g., arsenic). Fortunately, this ‘plume’ of impacted groundwater is usually confined within the original contaminant plume and is unlikely to adversely impact potable water supplies. This report summarizes available information on processes controlling the production and natural attenuation of SWQI parameters and can be used as a guide in understanding the magnitude, areal extent, and duration of SWQIs in ERB treatment zones and the natural attenuation of SWQI parameters as the dissolved solutes migrate downgradient with ambient groundwater flow. This information was compiled from a wide variety of sources including a survey and statistical analysis of SWQIs from 47 ERB sites, geochemical model simulations, field studies at sites where organic-rich materials have entered the subsurface (e.g., wastewater, landfill leachate, and hydrocarbon plumes), and basic information on physical, chemical, and biological processes in the subsurface. This information is then integrated to provide a general conceptual model of the major processes controlling SWQI production and attenuation.

  5. Improvements in Depression and Mental Health After Acceptance and Commitment Therapy are Related to Changes in Defusion and Values-Based Action.

    PubMed

    Bramwell, Kate; Richardson, Thomas

    2018-01-01

    Acceptance and commitment therapy (ACT) has been found to be effective for various mental health disorders but the processes through which it affects change remain unclear. Much process research in the area is on physical rather than mental health, and focuses on the broad concept of psychological flexibility with little research on specific mechanisms identified in theory such as fusion and values. This study explored whether there was a relationship between two of the main ACT processes (cognitive defusion and values) and levels of depression and distress. Thirty-three participants completed questionnaires at the start and end of their treatment measuring general mental health and distress, depression, levels of cognitive fusion and how much they were living in line with their values and how important their values were to them. Results showed reductions in levels of fusion and increases in values-based action were significantly related to reductions in distress and depression. There was no correlation between changes in values importance and changes in distress or depression. This study therefore suggests decreased defusion and increased values-based action is an important mechanism in the efficacy of ACT in those with depression and mental health problems. The study is however limited by a small sample size and future research with a sample large enough for mediation analysis would be beneficial.

  6. Industrial Applications of High Power Ultrasonics

    NASA Astrophysics Data System (ADS)

    Patist, Alex; Bates, Darren

    Since the change of the millennium, high-power ultrasound has become an alternative food processing technology applicable to large-scale commercial applications such as emulsification, homogenization, extraction, crystallization, dewatering, low-temperature pasteurization, degassing, defoaming, activation and inactivation of enzymes, particle size reduction, extrusion, and viscosity alteration. This new focus can be attributed to significant improvements in equipment design and efficiency during the late 1990 s. Like most innovative food processing technologies, high-power ultrasonics is not an off-the-shelf technology, and thus requires careful development and scale-up for each and every application. The objective of this chapter is to present examples of ultrasonic applications that have been successful at the commercialization stage, advantages, and limitations, as well as key learnings from scaling up an innovative food technology in general.

  7. Uranium Sequestration During Biostimulated Reduction and In Response to the Return of Oxic Conditions In Shallow Aquifers

    USGS Publications Warehouse

    Fuller, Christopher C.; Johnson, Kelly J.; Akstin, Katherine; Singer, David M.; Yabusaki, Steven B.; Fang, Yilin; Fuhrmann, M.

    2015-01-01

    A proposed approach for groundwater remediation of uranium contamination is to generate reducing conditions by stimulating the growth of microbial populations through injection of electron donor compounds into the subsurface. Sufficiently reducing conditions will result in reduction of soluble hexavalent uranium, U(VI), and precipitation of the less soluble +4 oxidation state uranium, U(IV). This process is termed biostimulated reduction. A key issue in the remediation of uranium (U) contamination in aquifers by biostimulated reduction is the long term stability of the sequestered uranium. Three flow-through column experiments using aquifer sediment were used to evaluate the remobilization of bioreduced U sequestered under conditions in which biostimulation extended well into sulfate reduction to enhance precipitation of reduced sulfur phases such as iron sulfides. One column received added ferrous iron, Fe(II), increasing production of iron sulfides, to test their effect on remobilization of the sequestered uranium, either by serving as a redox buffer by competing for dissolved oxygen, or by armoring the reduced uranium. During biostimulation of the ambient microbial population with acetate, dissolved uranium was lowered by a factor of 2.5 or more with continued removal for over 110 days of biostimulation, well after the onset of sulfate reduction at ~30 days. Sequestered uranium was essentially all U(IV) resulting from the formation of nano-particulate uraninite that coated sediment grains to a thickness of a few 10’s of microns, sometimes in association with S and Fe. A multicomponent biogeochemical reactive transport model simulation of column effluents during biostimulation was generally able to describe the acetate oxidation, iron, sulfate, and uranium reduction for all three columns using parameters derived from simulations of field scale biostimulation experiments. Columns were eluted with artificial groundwater at equilibrium with atmospheric oxygen to simulate the upper limit of dissolved oxygen in recharge water. Overall about 9% of total uranium removed from solution during biostimulation was remobilized. Release of U during oxic elution was a continuous process over 140 days with dissolved uranium concentrations about 0.2 and 0.8 aM for columns with and without ferrous iron addition, respectively. Uranium remaining on the sediment was in the reduced form. The prolonged period of biostimulation and concomitant sulfate reduction appears to limit the rate of U(IV) oxidative remobilization in contrast to a large release observed for columns in previous studies that did not undergo sulfate reduction. Although continued sulfate reduction may cause decreased permeability from precipitation of iron sulfide, the greater apparent stability of the sequestered U(IV) provided by the sustained biostimulation should be considered in design of field scale remediation efforts. Remobilization of uranium following biostimulated reduction should be tested further at the field scale.

  8. Can image enhancement allow radiation dose to be reduced whilst maintaining the perceived diagnostic image quality required for coronary angiography?

    PubMed Central

    Joshi, Anuja; Gislason-Lee, Amber J; Keeble, Claire; Sivananthan, Uduvil M

    2017-01-01

    Objective: The aim of this research was to quantify the reduction in radiation dose facilitated by image processing alone for percutaneous coronary intervention (PCI) patient angiograms, without reducing the perceived image quality required to confidently make a diagnosis. Methods: Incremental amounts of image noise were added to five PCI angiograms, simulating the angiogram as having been acquired at corresponding lower dose levels (10–89% dose reduction). 16 observers with relevant experience scored the image quality of these angiograms in 3 states—with no image processing and with 2 different modern image processing algorithms applied. These algorithms are used on state-of-the-art and previous generation cardiac interventional X-ray systems. Ordinal regression allowing for random effects and the delta method were used to quantify the dose reduction possible by the processing algorithms, for equivalent image quality scores. Results: Observers rated the quality of the images processed with the state-of-the-art and previous generation image processing with a 24.9% and 15.6% dose reduction, respectively, as equivalent in quality to the unenhanced images. The dose reduction facilitated by the state-of-the-art image processing relative to previous generation processing was 10.3%. Conclusion: Results demonstrate that statistically significant dose reduction can be facilitated with no loss in perceived image quality using modern image enhancement; the most recent processing algorithm was more effective in preserving image quality at lower doses. Advances in knowledge: Image enhancement was shown to maintain perceived image quality in coronary angiography at a reduced level of radiation dose using computer software to produce synthetic images from real angiograms simulating a reduction in dose. PMID:28124572

  9. Pilot scale treatment of chromite ore processing residue using sodium sulfide in single reduction and coupled reduction/stabilization processes.

    PubMed

    Velasco, Antonio; Ramírez, Martha; Hernández, Sergio; Schmidt, Winfried; Revah, Sergio

    2012-03-15

    Single Cr(VI) reduction and coupled reduction/stabilization (R/S) processes were evaluated at pilot scale to determine their effectiveness to treat chromite ore processing residue (COPR). Sodium sulfide was used as the reducing agent and cement, gypsum and lime were tested as the stabilizing agents. The pilot experiments were performed in a helical ribbon blender mixer with batches of 250 kg of COPR and mixing time up to 30 min. Na2S/Cr(VI) mass ratios of 4.6, 5.7 and 6.8 were evaluated in the single reduction process to treat COPR with Cr(VI) concentration of ≈4.2 g/kg. The R/S process was tested with a Na2S/Cr(VI) mass ratio of 5.7 and including stabilizing agents not exceeding 5% (w/w(COPR)), to treat COPR with a Cr(VI) content of ≈5.1g/kg. The single reduction process with a ratio of 6.8, reached Cr(VI) reduction efficiencies up to 97.6% in the first days, however these values decreased to around 93% after 380 days of storage. At this point the total Cr level was around 12.5 mg/L. Cr(VI) removal efficiencies exceeding 96.5% were reached and maintained during 380 days when the coupled R/S process was evaluated. Total Cr levels lower than 5 mg/l were attained at the initials days in all R/S batch tested, however after 380 days, concentrations below the regulatory limit were only found with gypsum (2%) as single agent and with a blend of cement (4%) and lime (1%). These results indicated that the coupled R/S process is an excellent alternative to stabilize COPR. Copyright © 2011 Elsevier B.V. All rights reserved.

  10. Optimized cutting and forming parameters for a robust collar drawing process for hot-rolled complex-phase steels

    NASA Astrophysics Data System (ADS)

    Kovacs, S.; Beier, T.; Woestmann, S.

    2017-09-01

    The demands on materials for automotive applications are steadily increasing. For chassis components, the trend is towards thinner and higher strength materials for weight and cost reduction. In view of attainable strengths of up to 1200 MPa for hot rolled materials, certain aspects need to be analysed and evaluated in advance in the development process using these materials. Collars in particular, for example in control arms, have been in focus for part and process design. Issues concerning edge and surface cracks are observed due to improper geometry and process layout. The hole expansion capability of the chosen material grade has direct influence on the achievable collar height. In general, shear cutting reduces the residual formability of blank edges and the hole expansion capability. In this paper, using the example of the complex phase steel CP-W® 800 of thyssenkrupp, it is shown how a suitable geometry of a collar and optimum shear cutting parameters can be chosen.

  11. Uncertainty Reduction for Stochastic Processes on Complex Networks

    NASA Astrophysics Data System (ADS)

    Radicchi, Filippo; Castellano, Claudio

    2018-05-01

    Many real-world systems are characterized by stochastic dynamical rules where a complex network of interactions among individual elements probabilistically determines their state. Even with full knowledge of the network structure and of the stochastic rules, the ability to predict system configurations is generally characterized by a large uncertainty. Selecting a fraction of the nodes and observing their state may help to reduce the uncertainty about the unobserved nodes. However, choosing these points of observation in an optimal way is a highly nontrivial task, depending on the nature of the stochastic process and on the structure of the underlying interaction pattern. In this paper, we introduce a computationally efficient algorithm to determine quasioptimal solutions to the problem. The method leverages network sparsity to reduce computational complexity from exponential to almost quadratic, thus allowing the straightforward application of the method to mid-to-large-size systems. Although the method is exact only for equilibrium stochastic processes defined on trees, it turns out to be effective also for out-of-equilibrium processes on sparse loopy networks.

  12. Effects of aging and divided attention on memory for items and their contexts.

    PubMed

    Craik, Fergus I M; Luo, Lin; Sakuta, Yuiko

    2010-12-01

    It is commonly found that memory for context declines disproportionately with aging, arguably due to a general age-related deficit in associative memory processes. One possible mechanism for such deficits is an age-related reduction in available processing resources. In two experiments we compared the effects of aging to the effects of division of attention in younger adults on memory for items and context. Using a technique proposed by Craik (1989), linear functions relating memory performance for items and their contexts were derived for a Young Full Attention group, a Young Divided Attention group, and an Older Adult group. Results suggested that the Old group showed an additional deficit in associative memory that was not mimicked by divided attention. It is speculated that both divided attention and aging are associated with a loss of available processing resources that may reflect inefficient frontal lobe functioning, whereas the additional age-related decrement in associative memory may reflect inefficient processing in medial-temporal regions. (c) 2010 APA, all rights reserved).

  13. Space Shuttle ET Friction Stir Weld Machines

    NASA Technical Reports Server (NTRS)

    Thompson, Jack M.

    2003-01-01

    NASA and Lockheed-Martin approached the FSW machine vendor community with a specification for longitudinal barrel production FSW weld machines and a shorter travel process development machine in June of 2000. This specification was based on three years of FSW process development on the Space Shuttle External Tank alloys, AL2 195-T8M4 and AL22 19-T87. The primary motivations for changing the ET longitudinal welds from the existing variable polarity Plasma Arc plasma weld process included: (1) Significantly reduced weld defect rates and related reduction in cycle time and uncertainty; (2) Many fewer process variables to control (5 vs. 17); (3) Fewer manufacturing steps; (4) Lower residual stresses and distortion; (5) Improved weld strengths, particularly at cryogenic temperatures; (6) Fewer hazards to production personnel. General Tool was the successful bidder. The equipment is at this writing installed and welding flight hardware. This paper is a means of sharing with the rest of the FSW community the unique features developed to assure NASA/L-M of successful production welds.

  14. The application of Lean Six Sigma methodology to reduce the risk of healthcare-associated infections in surgery departments.

    PubMed

    Montella, Emma; Di Cicco, Maria Vincenza; Ferraro, Anna; Centobelli, Piera; Raiola, Eliana; Triassi, Maria; Improta, Giovanni

    2017-06-01

    Nowadays, the monitoring and prevention of healthcare-associated infections (HAIs) is a priority for the healthcare sector. In this article, we report on the application of the Lean Six Sigma (LSS) methodology to reduce the number of patients affected by sentinel bacterial infections who are at risk of HAI. The LSS methodology was applied in the general surgery department by using a multidisciplinary team of both physicians and academics. Data on more than 20 000 patients who underwent a wide range of surgical procedures between January 2011 and December 2014 were collected to conduct the study using the departmental information system. The most prevalent sentinel bacteria were determined among the infected patients. The preintervention (January 2011 to December 2012) and postintervention (January 2013 to December 2014) phases were compared to analyze the effects of the methodology implemented. The methodology allowed the identification of variables that influenced the risk of HAIs and the implementation of corrective actions to improve the care process, thereby reducing the percentage of infected patients. The improved process resulted in a 20% reduction in the average number of hospitalization days between preintervention and control phases, and a decrease in the mean (SD) number of days of hospitalization amounted to 36 (15.68), with a data distribution around 3 σ. The LSS is a helpful strategy that ensures a significant decrease in the number of HAIs in patients undergoing surgical interventions. The implementation of this intervention in the general surgery departments resulted in a significant reduction in both the number of hospitalization days and the number of patients affected by HAIs. This approach, together with other tools for reducing the risk of infection (surveillance, epidemiological guidelines, and training of healthcare personnel), could be applied to redesign and improve a wide range of healthcare processes. © 2016 John Wiley & Sons, Ltd.

  15. Estimating the impact of reducing violence against female sex workers on HIV epidemics in Kenya and Ukraine: a policy modeling exercise.

    PubMed

    Decker, Michele R; Wirtz, Andrea L; Pretorius, Carel; Sherman, Susan G; Sweat, Michael D; Baral, Stefan D; Beyrer, Chris; Kerrigan, Deanna L

    2013-02-01

    Female sex workers (FSWs) worldwide suffer disproportionate burdens of HIV and gender-based violence. Despite evidence linking these threats, little is known about the potential HIV epidemic impact of reducing abuse. The Goals model approximated the impact of reducing violence against FSWs on HIV epidemics in Ukraine and Kenya, measured by reductions in new infections among FSWs and adults. Cumulative infections averted over a 5-year period, in which violence declined was calculated, relative to a status quo with no reduction. Projections held HIV interventions constant at baseline levels; subsequently, scenarios adjusted for planned expansion of antiretroviral therapy (ART) coverage. An approximate 25% reduction in incident HIV infections among FSWs was observed when physical or sexual violence was reduced; cumulative infections averted were 21,200 and 4700 in Kenya and Ukraine, respectively. Similar percent reductions were observed assuming ART coverage expansion, with approximately 18,200 and 4400 infections averted among FSWs in Kenya and Ukraine. New infections were also averted in the general population. Reducing violence against FSWs appears to impart significant reductions in new infections among FSWs and in the general adult population in both generalized and concentrated epidemics. Limitations provide direction to improve the precision of future estimates. © 2013 John Wiley & Sons A/S.

  16. Impacts of large dams on downstream flow conditions of rivers: Aggradation and reduction of the Medjerda channel capacity downstream of the Sidi Salem dam (Tunisia)

    NASA Astrophysics Data System (ADS)

    Zahar, Yadh; Ghorbel, Abdelmajid; Albergel, Jean

    2008-04-01

    SummarySince the opening of the Sidi Salem dam on the watercourse of the Medjerda, in 1981, an alarming narrowing of the riverbed in the lower valley has been observed. This geo-morphological change is attributed to different factors ranking from the reduction in the discharge flows, which used to clean out the riverbed to the periodic releases of turbid water undertaken to remove the silt deposition inside the reservoir, which increased the sediment deposition in the downstream channel. Other smaller hydraulic projects are also held responsible for the loss of the water velocity including a series of concrete sills meant to raise water levels, numerous cross bridges and the management of the downstream Laroussia dam regulating the discharge from the Cap Bon canal. The above anthropogenic factors, in conjunction with natural topographical conditions characterized by a generally shallow slope and a very sinuous watercourse, led to an extremely rapid aggradation of the downstream channel-bed. This paper proposes an analysis of this process and argues that the resulting reduction in channel capacity is one of the major causes of the large floods experienced in the country since 1996.

  17. Oscillations and patterns in a model of simultaneous CO and C2H2 oxidation and NO(x) reduction in a cross-flow reactor.

    PubMed

    Hadač, Otto; Kohout, Martin; Havlica, Jaromír; Schreiber, Igor

    2015-03-07

    A model describing simultaneous catalytic oxidation of CO and C2H2 and reduction of NOx in a cross-flow tubular reactor is explored with the aim of relating spatiotemporal patterns to specific pathways in the mechanism. For that purpose, a detailed mechanism proposed for three-way catalytic converters is split into two subsystems, (i) simultaneous oxidation of CO and C2H2, and (ii) oxidation of CO combined with NOx reduction. The ability of these two subsystems to display mechanism-specific dynamical effects is studied initially by neglecting transport phenomena and applying stoichiometric network and bifurcation analyses. We obtain inlet temperature - inlet oxygen concentration bifurcation diagrams, where each region possessing specific dynamics - oscillatory, bistable and excitable - is associated with a dominant reaction pathway. Next, the spatiotemporal behaviour due to reaction kinetics combined with transport processes is studied. The observed spatiotemporal patterns include phase waves, travelling fronts, pulse waves and spatiotemporal chaos. Although these types of pattern occur generally when the kinetic scheme possesses autocatalysis, we find that some of their properties depend on the underlying dominant reaction pathway. The relation of patterns to specific reaction pathways is discussed.

  18. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Couth, R.; Trois, C., E-mail: troisc@ukzn.ac.za

    Highlights: Black-Right-Pointing-Pointer This is a compendium on GHG reductions via improved waste strategies in Africa. Black-Right-Pointing-Pointer This note provides a strategic framework for Local Authorities in Africa. Black-Right-Pointing-Pointer Assists LAs to select Zero Waste scenarios and achieve sustained GHG reduction. - Abstract: Only few Clean Development Mechanism (CDM) projects (traditionally focussed on landfill gas combustion) have been registered in Africa if compared to similar developing countries. The waste hierarchy adopted by many African countries clearly shows that waste recycling and composting projects are generally the most sustainable. This paper undertakes a sustainability assessment for practical waste treatment and disposal scenariosmore » for Africa and makes recommendations for consideration. The appraisal in this paper demonstrates that mechanical biological treatment of waste becomes more financially attractive if established through the CDM process. Waste will continue to be dumped in Africa with increasing greenhouse gas emissions produced, unless industrialised countries (Annex 1) fund carbon emission reduction schemes through a replacement to the Kyoto Protocol. Such a replacement should calculate all of the direct and indirect carbon emission savings and seek to promote public-private partnerships through a concerted support of the informal sector.« less

  19. Inactivation of Escherichia Coli O157:H7 and Salmonella Enterica on Blueberries in Water Using Ultraviolet Light.

    PubMed

    Liu, Chuhan; Huang, Yaoxin; Chen, Haiqiang

    2015-07-01

    Ultraviolet light (UV) has antimicrobial effects, but the shadowing effect has limited its application. In this study, a novel setup using UV processing in agitated water was developed to inactivate Escherichia coli O157:H7 and Salmonella on blueberries. Blueberries were dip- or spot-inoculated with E. coli or Salmonella. Blueberries inoculated with E. coli were treated for 2 to 10 min with UV directly (dry UV) or immersed in agitated water during UV treatment (wet UV). E. coli was most easily killed on spot-inoculated blueberries with a 5.2-log reduction after 10-min wet UV treatment. Dip-inoculated blueberries were the most difficult to be decontaminated with only 1.6-log reduction after 10-min wet UV treatment. Wet UV treatment generally showed higher efficacies than dry UV treatment, achieving an average of 1.4 log more reduction for spot-inoculated blueberries. For dip-inoculated blueberries, chlorine washing and UV treatments were less effective, achieving <2 log reductions of E. coli. Thus, the efficacy of combinations of wet UV with sodium dodecyl sulfate (SDS), levulinic acid, or chlorine was evaluated. Inoculated blueberries were UV-treated while being immersed in agitated water containing 100 ppm SDS, 0.5% levulinic acid or 10 ppm chlorine. The 3 chemicals did not significantly enhance the wet UV treatment. Findings of this study suggest that UV treatment could be used as an alternative to chlorine washing for blueberries and potentially for other fresh produce. A novel UV light system for decontamination of blueberries in water was developed and evaluated. Results demonstrated that the decontamination efficacy of this system was generally as effective as chlorine washing, indicating that it could potentially be used as an alternative to chlorine washing for blueberries and other fresh produce. © 2015 Institute of Food Technologists®

  20. Reduction in Force: The Legal Aspects.

    ERIC Educational Resources Information Center

    Ware, Martha L.

    Six legal issues surrounding a school district's reduction in force are described in this twelfth chapter in a book on school law. First, the courts generally hold that the school board must prove that a reduction in force (RIF) is inescapable. The second issue revolves around which positions and employees are being eliminated. In deciding such…

  1. 12 CFR 404.10 - Fee waivers or reductions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Fee waivers or reductions. 404.10 Section 404.10 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES INFORMATION DISCLOSURE Procedures for Disclosure of Records Under the Freedom of Information Act. § 404.10 Fee waivers or reductions. (a) General...

  2. 12 CFR 997.2 - Reduction of the payment term.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Reduction of the payment term. 997.2 Section 997.2 Banks and Banking FEDERAL HOUSING FINANCE BOARD NON-BANK SYSTEM ENTITIES RESOLUTION FUNDING CORPORATION OBLIGATIONS OF THE BANKS § 997.2 Reduction of the payment term. (a) Generally. The Finance Board...

  3. Evaluation of selected chemical processes for production of low-cost silicon

    NASA Technical Reports Server (NTRS)

    Blocher, J. M., Jr.; Browning, M. F.; Wilson, W. J.; Carmichael, D. C.

    1976-01-01

    Plant construction costs and manufacturing costs were estimated for the production of solar-grade silicon by the reduction of silicon tetrachloride in a fluidized bed of seed particles, and several modifications of the iodide process using either thermal decomposition on heated filaments (rods) or hydrogen reduction in a fluidized bed of seed particles. Energy consumption data for the zinc reduction process and each of the iodide process options are given and all appear to be acceptable from the standpoint of energy pay back. Information is presented on the experimental zinc reduction of SiCl4 and electrolytic recovery of zinc from ZnCl2. All of the experimental work performed thus far has supported the initial assumption as to technical feasibility of producing semiconductor silicon by the zinc reduction or iodide processes proposed. The results of a more thorough thermodynamic evaluation of the iodination of silicon oxide/carbon mixtures are presented which explain apparent inconsistencies in an earlier cursory examination of the system.

  4. Turbulent drag reduction for external flows

    NASA Technical Reports Server (NTRS)

    Bushnell, D. M.

    1985-01-01

    A summary of turbulent drag reduction approaches applicable to external flows is given. Because relatively recent and exhaustive reviews exist for laminar flow control and polymer (hydrodynamic) drag reduction, the focus here is upon the emerging areas of nonplanar geometry and large-eddy alteration. Turbulent control techniques for air generally result in modest (but technologically significant) drag reductions (order of 20 percent or less), whereas hydrodynamic approaches can yield drag reductions the order of 70 percent. Suggestions are included for alternative concepts and optimization of existing approaches.

  5. Turbulent drag reduction for external flows

    NASA Technical Reports Server (NTRS)

    Bushnell, D. M.

    1983-01-01

    Paper presents a review and summary of turbulent drag reduction approaches applicable to external flows. Because relatively recent and exhaustive reviews exist for laminar flow control and polymer (hydrodynamic) drag reduction, the paper focuses upon the emerging areas of nonplanar geometry and large eddy alteration. Turbulent control techniques for air generally result in modest (but technologically significant) drag reductions (order of 20 percent or less) whereas hydrodynamic approaches can yield drag reductions the order of 70 percent. Paper also includes suggestions for alternative concepts and optimization of existing approaches.

  6. Solving Disparities Through Payment And Delivery System Reform: A Program To Achieve Health Equity.

    PubMed

    DeMeester, Rachel H; Xu, Lucy J; Nocon, Robert S; Cook, Scott C; Ducas, Andrea M; Chin, Marshall H

    2017-06-01

    Payment systems generally do not directly encourage or support the reduction of health disparities. In 2013 the Finding Answers: Solving Disparities through Payment and Delivery System Reform program of the Robert Wood Johnson Foundation sought to understand how alternative payment models might intentionally incorporate a disparities-reduction component to promote health equity. A qualitative analysis of forty proposals to the program revealed that applicants generally did not link payment reform tightly to disparities reduction. Most proposed general pay-for-performance, global payment, or shared savings plans, combined with multicomponent system interventions. None of the applicants proposed making any financial payments contingent on having successfully reduced disparities. Most applicants did not address how they would optimize providers' intrinsic and extrinsic motivation to reduce disparities. A better understanding of how payment and care delivery models might be designed and implemented to reduce health disparities is essential. Project HOPE—The People-to-People Health Foundation, Inc.

  7. Hydrogen Plasma Processing of Iron Ore

    NASA Astrophysics Data System (ADS)

    Sabat, Kali Charan; Murphy, Anthony B.

    2017-06-01

    Iron is currently produced by carbothermic reduction of oxide ores. This is a multiple-stage process that requires large-scale equipment and high capital investment, and produces large amounts of CO2. An alternative to carbothermic reduction is reduction using a hydrogen plasma, which comprises vibrationally excited molecular, atomic, and ionic states of hydrogen, all of which can reduce iron oxides, even at low temperatures. Besides the thermodynamic and kinetic advantages of a hydrogen plasma, the byproduct of the reaction is water, which does not pose any environmental problems. A review of the theory and practice of iron ore reduction using a hydrogen plasma is presented. The thermodynamic and kinetic aspects are considered, with molecular, atomic and ionic hydrogen considered separately. The importance of vibrationally excited hydrogen molecules in overcoming the activation energy barriers, and in transferring energy to the iron oxide, is emphasized. Both thermal and nonthermal plasmas are considered. The thermophysical properties of hydrogen and argon-hydrogen plasmas are discussed, and their influence on the constriction and flow in the of arc plasmas is considered. The published R&D on hydrogen plasma reduction of iron oxide is reviewed, with both the reduction of molten iron ore and in-flight reduction of iron ore particles being considered. Finally, the technical and economic feasibility of the process are discussed. It is shown that hydrogen plasma processing requires less energy than carbothermic reduction, mainly because pelletization, sintering, and cokemaking are not required. Moreover, the formation of the greenhouse gas CO2 as a byproduct is avoided. In-flight reduction has the potential for a throughput at least equivalent to the blast furnace process. It is concluded that hydrogen plasma reduction of iron ore is a potentially attractive alternative to standard methods.

  8. Consumer understanding of sugars claims on food and drink products

    PubMed Central

    Patterson, N J; Sadler, M J; Cooper, J M

    2012-01-01

    Consumer understanding of nutrition and health claims is a key aspect of current regulations in the European Union (EU). In view of this, qualitative and quantitative research techniques were used to investigate consumer awareness and understanding of product claims in the UK, focusing particularly on nutrition claims relating to sugars. Both research methods identified a good awareness of product claims. No added sugars claims were generally preferred to reduced sugars claims, and there was a general assumption that sweeteners and other ingredients would be added in place of sugars. However, there was little awareness of the level of sugar reduction and the associated calorie reduction in products when reduced sugars claims were made on pack. In focus groups, participants felt deceived if sugar reduction claims were being made without a significant reduction in calories. This was reinforced in the quantitative research which showed that respondents expected a similar and meaningful level of calorie reduction to the level of sugar reduction. The research also identified consumer confusion around the calorie content of different nutrients, including over-estimation of the calorie content of sugars. This is crucial to consumers' expectations as they clearly link sugar to calories and therefore expect a reduction in sugar content to deliver a reduction in calorie content. PMID:22973161

  9. Generalization of the photo process window and its application to OPC test pattern design

    NASA Astrophysics Data System (ADS)

    Eisenmann, Hans; Peter, Kai; Strojwas, Andrzej J.

    2003-07-01

    From the early development phase up to the production phase, test pattern play a key role for microlithography. The requirement for test pattern is to represent the design well and to cover the space of all process conditions, e.g. to investigate the full process window and all other process parameters. This paper shows that the current state-of-the-art test pattern do not address these requirements sufficiently and makes suggestions for a better selection of test pattern. We present a new methodology to analyze an existing layout (e.g. logic library, test pattern or full chip) for critical layout situations which does not need precise process data. We call this method "process space decomposition", because it is aimed at decomposing the process impact to a layout feature into a sum of single independent contributions, the dimensions of the process space. This is a generalization of the classical process window, which examines defocus and exposure dependency of given test pattern, e.g. CD value of dense and isolated lines. In our process space we additionally define the dimensions resist effects, etch effects, mask error and misalignment, which describe the deviation of the printed silicon pattern from its target. We further extend it by the pattern space using a product based layout (library, full chip or synthetic test pattern). The criticality of pattern is defined by their deviation due to aerial image, their sensitivity to the respective dimension or several combinations of these. By exploring the process space for a given design, the method allows to find the most critical patterns independent of specific process parameters. The paper provides examples for different applications of the method: (1) selection of design oriented test pattern for lithography development (2) test pattern reduction in process characterization (3) verification/optimization of printability and performance of post processing procedures (like OPC) (4) creation of a sensitive process monitor.

  10. Characteristics of sludge reduction in an integrated pretreatment and aerobic digestion process.

    PubMed

    Hwang, S; Jang, H; Lee, M; Song, J; Kim, S

    2006-01-01

    In this study, integrated pretreatments and aerobic digestion processes were investigated in order to provide a feasible alternative that can achieve effective sludge reduction. An ozone treatment in the presence of ionic manganese, a catalyst, increased the sludge reduction ratio three times higher than that of a single ozonation, presumably due to an increase in OH radical production. The ozone treatment yielded the effective sludge reduction ratio with an increasing ozone dosage, and an effective dosage of the catalyst was found to be 4 mg-Mn/g-TS. When a mechanical pretreatment and an ozone/catalyst were applied in a series, the integrated process, even at a half mechanical intensity and a half level of ozone dosage, showed higher and faster sludge reduction than each single process did. In addition, the integrated pretreatment process showed the highest dewaterability of the treated sludges. A ratio of sludge cake generation, which was newly introduced to quantify overall performance of sludge treatment processes, showed that the integrated pretreatment followed by the aerobic digestion yielded approximately a half of the sludge cake volume compared to the single aerobic digestion. Therefore, the integrated pretreatment can be a feasible method for the effective reduction of total suspended solid and the final volume.

  11. High-performance data processing using distributed computing on the SOLIS project

    NASA Astrophysics Data System (ADS)

    Wampler, Stephen

    2002-12-01

    The SOLIS solar telescope collects data at a high rate, resulting in 500 GB of raw data each day. The SOLIS Data Handling System (DHS) has been designed to quickly process this data down to 156 GB of reduced data. The DHS design uses pools of distributed reduction processes that are allocated to different observations as needed. A farm of 10 dual-cpu Linux boxes contains the pools of reduction processes. Control is through CORBA and data is stored on a fibre channel storage area network (SAN). Three other Linux boxes are responsible for pulling data from the instruments using SAN-based ringbuffers. Control applications are Java-based while the reduction processes are written in C++. This paper presents the overall design of the SOLIS DHS and provides details on the approach used to control the pooled reduction processes. The various strategies used to manage the high data rates are also covered.

  12. Degradation and ecotoxicity of dye Reactive Black 5 after reductive-oxidative process : Environmental Science and Pollution Research.

    PubMed

    Cuervo Lumbaque, Elisabeth; Gomes, Monike Felipe; Da Silva Carvalho, Vanessa; de Freitas, Adriane Martins; Tiburtius, Elaine Regina Lopes

    2017-03-01

    This research paper describes the study of a reduction-oxidation system using commercial steel wool (Fe 0 ) and H 2 O 2 for degradation of the dye Reactive Black 5 and aromatic compounds in water. The reductive process alone allowed the almost complete removal of color (97 ± 1 %) after 60 min of reaction. The decrease in spectral area (λ = 599 nm) associated with the chromophore group indicates breakage of the azo bonds. Moreover, the significant change in UV spectra can be associated with the formation of aromatic amines. Regarding the transformation products, a spectrophotometric method based on the diazotization reaction was employed to identify aromatic amines after reductive process, using sulfanilic acid as a model of aromatic amines. In addition, association with Fenton reagents improved the efficiency in the system with 93 ± 1 % degradation of intermediates formed during the reductive process. Ecotoxicological analysis revealed that the dye solution, after the reductive and oxidative processes, was not toxic to Lactuca sativa seeds. For Daphnia magna, the EC 50 (%) values observed revealed that dye solution has an EC 50 (%) = 74.1 and after reductive process, the toxicity increased (EC 50 (%) = 63.5), which might be related to the formation of aromatic amines. However, after the Fenton process, the EC 50 (%) was >100. These results demonstrated that the Fenton reaction using steel wool as an iron source was very efficient to decrease color, aromatic transformation products, and the ecotoxicity of Reactive Black 5 in solution.

  13. 75 FR 30844 - General Mills, Inc.; Withdrawal of Food Additive Petition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-02

    ... for the reduction of pathogens and other microorganisms in aqueous sugar solutions and potable water... reduction of pathogens and other microorganisms in aqueous sugar solutions and potable water intended for...

  14. High Pressure Low NOx Emissions Research: Recent Progress at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Chi-Ming, Lee; Tacina, Kathleen M.; Wey, Changlie

    2007-01-01

    In collaboration with U.S. aircraft engine companies, NASA Glenn Research Center has contributed to the advancement of low emissions combustion systems. For the High Speed Research Program (HSR), a 90% reduction in nitrogen oxides (NOx) emissions (relative to the then-current state of the art) has been demonstrated in sector rig testing at General Electric Aircraft Engines (GEAE). For the Advanced Subsonic Technology Program (AST), a 50% reduction in NOx emissions relative to the 1996 International Civil Aviation Organization (ICAO) standards has been at demonstrated in sector rigs at both GEAE and Pratt & Whitney (P&W). During the Ultra Efficient Engine Technology Program (UEET), a 70% reduction in NOx emissions, relative to the 1996 ICAO standards, was achieved in sector rig testing at Glenn in the world class Advanced Subsonic Combustion Rig (ASCR) and at contractor facilities. Low NOx combustor development continues under the Fundamental Aeronautics Program. To achieve these reductions, experimental and analytical research has been conducted to advance the understanding of emissions formation in combustion processes. Lean direct injection (LDI) concept development uses advanced laser-based non-intrusive diagnostics and analytical work to complement the emissions measurements and to provide guidance for concept improvement. This paper describes emissions results from flametube tests of a 9- injection-point LDI fuel/air mixer tested at inlet pressures up to 5500 kPa. Sample results from CFD and laser diagnostics are also discussed.

  15. NASA Glenn High Pressure Low NOx Emissions Research

    NASA Technical Reports Server (NTRS)

    Tacina, Kathleen M.; Wey, Changlie

    2008-01-01

    In collaboration with U.S. aircraft engine companies, NASA Glenn Research Center has contributed to the advancement of low emissions combustion systems. For the High Speed Research Program (HSR), a 90% reduction in nitrogen oxides (NOx) emissions (relative to the then-current state of the art) has been demonstrated in sector rig testing at General Electric Aircraft Engines (GEAE). For the Advanced Subsonic Technology Program (AST), a 50% reduction in NOx emissions relative to the 1996 International Civil Aviation Organization (ICAO) standards has been demonstrated in sector rigs at both GEAE and Pratt & Whitney (P&W). During the Ultra Efficient Engine Technology Program (UEET), a 70% reduction in NOx emissions, relative to the 1996 ICAO standards, was achieved in sector rig testing at Glenn in the world class Advanced Subsonic Combustion Rig (ASCR) and at contractor facilities. Low NOx combustor development continues under the Fundamental Aeronautics Program. To achieve these reductions, experimental and analytical research has been conducted to advance the understanding of emissions formation in combustion processes. Lean direct injection (LDI) concept development uses advanced laser-based non-intrusive diagnostics and analytical work to complement the emissions measurements and to provide guidance for concept improvement. This paper describes emissions results from flametube tests of a 9-injection-point LDI fuel/air mixer tested at inlet pressures up to 5500 kPa. Sample results from CFD and laser diagnostics are also discussed.

  16. Digitization and reduction of old astronomical plates of natural satellites

    NASA Astrophysics Data System (ADS)

    Yan, D.; Qiao, R. C.; Dourneau, G.; Yu, Y.; Zhang, H. Y.; Cheng, X.; Xi, X. J.

    2016-04-01

    Old astrophotographic plates are precious sources of historical data for astronomical studies, especially regarding the improvement of natural satellite orbits. Today, with the advent of new, accurate techniques, these old data can be re-processed so as to give positions that are much more accurate than those initially obtained. Various recent projects, including our Chinese project, have involved measuring and reducing these old plates again. Here we present a method for measurement and reduction that involves the digitization of plates using an advanced commercial scanner, namely the EPSON 10000 XL. We selected a set of 27 plates of the satellites of Jupiter, Saturn and Uranus taken from 1987 to 1990. A total of 125 satellite positions were derived from the new measurement and reduction of these plates using the UCAC4 catalogue. A comparison of the new observed positions with recent ephemerides has shown a general consistency with satellite theory of about 100 mas. The new positions present an accuracy equivalent to the most recent CCD observations, and better than the original positions. Moreover, nearly 30 per cent of the 125 positions obtained in this work are published for the first time here. This paper is a preliminary contribution to the larger project of new measurements and reductions of all the old Chinese plates of natural satellites, which should allow further improvements in the knowledge of the orbits of these satellites.

  17. Reductive stripping process for uranium recovery from organic extracts

    DOEpatents

    Hurst, F.J. Jr.

    1983-06-16

    In the reductive stripping of uranium from an organic extractant in a uranium recovery process, the use of phosphoric acid having a molarity in the range of 8 to 10 increases the efficiency of the reductive stripping and allows the strip step to operate with lower aqueous to organic recycle ratios and shorter retention time in the mixer stages. Under these operating conditions, less solvent is required in the process, and smaller, less expensive process equipment can be utilized. The high strength H/sub 3/PO/sub 4/ is available from the evaporator stage of the process.

  18. Reductive stripping process for uranium recovery from organic extracts

    DOEpatents

    Hurst, Jr., Fred J.

    1985-01-01

    In the reductive stripping of uranium from an organic extractant in a uranium recovery process, the use of phosphoric acid having a molarity in the range of 8 to 10 increases the efficiency of the reductive stripping and allows the strip step to operate with lower aqueous to organic recycle ratios and shorter retention time in the mixer stages. Under these operating conditions, less solvent is required in the process, and smaller, less expensive process equipment can be utilized. The high strength H.sub.3 PO.sub.4 is available from the evaporator stage of the process.

  19. [Predicting the impact of climate change in the next 40 years on the yield of maize in China].

    PubMed

    Ma, Yu-ping; Sun, Lin-li; E, You-hao; Wu, Wei

    2015-01-01

    Climate change will significantly affect agricultural production in China. The combination of the integral regression model and the latest climate projection may well assess the impact of future climate change on crop yield. In this paper, the correlation model of maize yield and meteorological factors was firstly established for different provinces in China by using the integral regression method, then the impact of climate change in the next 40 years on China's maize production was evaluated combined the latest climate prediction with the reason be ing analyzed. The results showed that if the current speeds of maize variety improvement and science and technology development were constant, maize yield in China would be mainly in an increasing trend of reduction with time in the next 40 years in a range generally within 5%. Under A2 climate change scenario, the region with the most reduction of maize yield would be the Northeast except during 2021-2030, and the reduction would be generally in the range of 2.3%-4.2%. Maize yield reduction would be also high in the Northwest, Southwest and middle and lower reaches of Yangtze River after 2031. Under B2 scenario, the reduction of 5.3% in the Northeast in 2031-2040 would be the greatest across all regions. Other regions with considerable maize yield reduction would be mainly in the Northwest and the Southwest. Reduction in maize yield in North China would be small, generally within 2%, under any scenarios, and that in South China would be almost unchanged. The reduction of maize yield in most regions would be greater under A2 scenario than under B2 scenario except for the period of 2021-2030. The effect of the ten day precipitation on maize yield in northern China would be almost positive. However, the effect of ten day average temperature on yield of maize in all regions would be generally negative. The main reason of maize yield reduction was temperature increase in most provinces but precipitation decrease in a few provinces. Assessments of the future change of maize yield in China based on the different methods were not consistent. Further evaluation needs to consider the change of maize variety and scientific and technological progress, and to enhance the reliability of evaluation models.

  20. Desulfofrigus sp. prevails in sulfate-reducing dilution cultures from sediments of the Benguela upwelling area.

    PubMed

    Kraft, Beate; Engelen, Bert; Goldhammer, Tobias; Lin, Yu-Shih; Cypionka, Heribert; Könneke, Martin

    2013-04-01

    Sediments of coastal upwelling areas are generally characterized by a high content of organic carbon that is mainly degraded via anaerobic microbial processes including sulfate reduction as a major terminal oxidation step. Despite the high importance of sulfate reduction in these sediments, the identity of sulfate-reducing bacteria (SRB) has remained almost unknown. Here, we applied a cultivation-based approach using selective enrichment conditions to study the diversity and distribution of active SRB in sediments along a transect perpendicular to the continental slope off the coast of Namibia (Meteor-cruise M76/1). To promote growth of the most abundant SRB, dilution series were prepared and amended with hydrogen, acetate, or a mixture of monomers representing typical substrates for SRB. Growth of SRB could be detected in the presence of all electron donors and from sediment down to 4 m depth. 16S rRNA gene-based DGGE analysis and sequencing revealed the predominance of SRB related to psychrophiles in particular to the genus Desulfofrigus, which made up 1 % of the total microbial community, accounting for an absolute abundance of up to 4.8 × 10(7)  cells mL(-1) . In general, the abundance of cultured SRB changed with depth and between the different sampling sites and correlated with the content of organic carbon as previously reported. Growth of chemolithotrophic SRB in relatively high dilution steps and the enrichment of methanogens as well as acetogens from deeper sediment point to a competition between hydrogen-utilizing microbial processes and their biogeochemical significance in deep sediment layers of the Benguela upwelling area. © 2012 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.

  1. Facing the fear--clinical and neural effects of cognitive behavioural and pharmacotherapy in panic disorder with agoraphobia.

    PubMed

    Liebscher, Carolin; Wittmann, André; Gechter, Johanna; Schlagenhauf, Florian; Lueken, Ulrike; Plag, Jens; Straube, Benjamin; Pfleiderer, Bettina; Fehm, Lydia; Gerlach, Alexander L; Kircher, Tilo; Fydrich, Thomas; Deckert, Jürgen; Wittchen, Hans-Ulrich; Heinz, Andreas; Arolt, Volker; Ströhle, Andreas

    2016-03-01

    Cognitive behavioural therapy (CBT) and pharmacological treatment with selective serotonin or serotonin-noradrenalin reuptake inhibitors (SSRI/SSNRI) are regarded as efficacious treatments for panic disorder with agoraphobia (PD/AG). However, little is known about treatment-specific effects on symptoms and neurofunctional correlates. We used a comparative design with PD/AG patients receiving either two types of CBT (therapist-guided (n=29) or non-guided exposure (n=22)) or pharmacological treatment (SSRI/SSNRI; n=28) as well as a wait-list control group (WL; n=15) to investigate differential treatment effects in general aspects of fear and depression (Hamilton Anxiety Rating Scale HAM-A and Beck Depression Inventory BDI), disorder-specific symptoms (Mobility Inventory MI, Panic and Agoraphobia Scale subscale panic attacks PAS-panic, Anxiety Sensitivity Index ASI, rating of agoraphobic stimuli) and neurofunctional substrates during symptom provocation (Westphal-Paradigm) using functional magnetic resonance imaging (fMRI). Comparisons of neural activation patterns also included healthy controls (n=29). Both treatments led to a significantly greater reduction in panic attacks, depression and general anxiety than the WL group. The CBT groups, in particular, the therapist-guided arm, had a significantly greater decrease in avoidance, fear of phobic situations and anxiety symptoms and reduction in bilateral amygdala activation while the processing of agoraphobia-related pictures compared to the SSRI/SSNRI and WL groups. This study demonstrates that therapist-guided CBT leads to a more pronounced short-term impact on agoraphobic psychopathology and supports the assumption of the amygdala as a central structure in a complex fear processing system as well as the amygdala's involvement in the fear system's sensitivity to treatment. Copyright © 2016 Elsevier B.V. and ECNP. All rights reserved.

  2. An investigation of the reduction of carbon dioxide in a silent electric discharge

    NASA Technical Reports Server (NTRS)

    Luce, R. S.; Greenough, B. (Editor)

    1978-01-01

    The reduction of CO2 to O2 and CO in a silent electric discharge was studied. It was found that current alone (in the ionized plasma induced by the silent electric discharge) was reponsible for the CO2 reduction process. Voltage and frequency were important only in so far as they induced current in the plasma. Pressure and temperature were of minimum influence in the process. The large power consumption in the process was recognized as resulting from the low power factor of the reactor vessel which electrically behaved like a capacitor. The power factor was subsequently improved by adding an inductive element to make the reactor vessel capacitance part of a resonant circuit. It was found that the CO2 reduction process was most efficient in terms of power vs reduction rate when a voltage was employed that was only slightly higher than that needed to induce the plasma.

  3. Fuzzy Relational Databases: Representational Issues and Reduction Using Similarity Measures.

    ERIC Educational Resources Information Center

    Prade, Henri; Testemale, Claudette

    1987-01-01

    Compares and expands upon two approaches to dealing with fuzzy relational databases. The proposed similarity measure is based on a fuzzy Hausdorff distance and estimates the mismatch between two possibility distributions using a reduction process. The consequences of the reduction process on query evaluation are studied. (Author/EM)

  4. Geochemical modeling of iron, sulfur, oxygen and carbon in a coastal plain aquifer

    NASA Astrophysics Data System (ADS)

    Brown, C. J.; Schoonen, M. A. A.; Candela, J. L.

    2000-11-01

    Fe(III) reduction in the Magothy aquifer of Long Island, NY, results in high dissolved-iron concentrations that degrade water quality. Geochemical modeling was used to constrain iron-related geochemical processes and redox zonation along a flow path. The observed increase in dissolved inorganic carbon is consistent with the oxidation of sedimentary organic matter coupled to the reduction of O 2 and SO 42- in the aerobic zone, and to the reduction of SO 42- in the anaerobic zone; estimated rates of CO 2 production through reduction of Fe(III) were relatively minor by comparison. The rates of CO 2 production calculated from dissolved inorganic carbon mass transfer (2.55×10 -4 to 48.6×10 -4 mmol l -1 yr-1) generally were comparable to the calculated rates of CO 2 production by the combined reduction of O 2, Fe(III) and SO 42- (1.31×10 -4 to 15×10 -4 mmol l -1 yr-1). The overall increase in SO 42- concentrations along the flow path, together with the results of mass-balance calculations, and variations in δ34S values along the flow path indicate that SO 42- loss through microbial reduction is exceeded by SO 42- gain through diffusion from sediments and through the oxidation of FeS 2. Geochemical and microbial data on cores indicate that Fe(III) oxyhydroxide coatings on sediment grains in local, organic carbon- and SO 42--rich zones have been depleted by microbial reduction and resulted in localized SO 42--reducing zones in which the formation of iron disulfides decreases dissolved iron concentrations. These localized zones of SO 42- reduction, which are important for assessing zones of low dissolved iron for water-supply development, could be overlooked by aquifer studies that rely only on groundwater data from well-water samples for geochemical modeling.

  5. The role of coping and general psychopathology in the prediction of treatment outcome in eating disorders.

    PubMed

    Davies, Michelle M; Bekker, Marrie H J; Roosen, Maries A

    2011-01-01

    This study examined coping and general psychopathology as possible predictors of reduction of eating disorder symptomatology. Assessment took place at pre- and post-treatment for all eating disorder patients (N = 93). Eating pattern and behavior were measured, as well as BMI and general psychopathology. As hypothesized, the coping strategies and comorbidity of respondents at pre-treatment contributed significantly to their outcome scores, and behavior aspects associated with eating disorders. Active coping strategies and low levels of general psychopathology predicted better outcome scores. This implies that active coping strategies and low levels of accompanying psychopathology at pre-treatment could be indicators of good chances for reduction of eating disorder symptomatology such as emotional eating, bulimia symptomatology, ineffectiveness, and introceptive awareness.

  6. Pre-Processed Recursive Lattice Reduction for Complexity Reduction in Spatially and Temporally Correlated MIMO Channels

    NASA Astrophysics Data System (ADS)

    An, Chan-Ho; Yang, Janghoon; Jang, Seunghun; Kim, Dong Ku

    In this letter, a pre-processed lattice reduction (PLR) scheme is developed for the lattice reduction aided (LRA) detection of multiple input multiple-output (MIMO) systems in spatially correlated channel. The PLR computes the LLL-reduced matrix of the equivalent matrix, which is the product of the present channel matrix and unimodular transformation matrix for LR of spatial correlation matrix, rather than the present channel matrix itself. In conjunction with PLR followed by recursive lattice reduction (RLR) scheme [7], pre-processed RLR (PRLR) is shown to efficiently carry out the LR of the channel matrix, especially for the burst packet message in spatially and temporally correlated channel while matching the performance of conventional LRA detection.

  7. Cancer risk elicitation and communication: lessons from the psychology of risk perception.

    PubMed

    Klein, William M P; Stefanek, Michael E

    2007-01-01

    Cancer risk perceptions are a key predictor of risk-reduction practices, health behaviors, and processing of cancer information. Nevertheless, patients and the general public (as well as health care providers) exhibit a number of errors and biases in the way they think about risk, such that their risk perceptions and decisions deviate greatly from those prescribed by normative decision models and by experts in risk assessment. For example, people are more likely to engage in screening behaviors such as mammography when faced with loss-based messages than gain-framed messages, and they often ignore the base rate of a given disease when assessing their own risk of obtaining this disease. In this article, we review many of the psychological processes that underlie risk perception and discuss how these processes lead to such deviations. Among these processes are difficulties with use of numerical information (innumeracy), cognitive processes (eg, use of time-saving heuristics), motivational factors (eg, loss and regret aversion), and emotion. We conclude with suggestions for future research in the area, as well as implications for improving the elicitation and communication of personal cancer risk.

  8. Data Processing and Text Mining Technologies on Electronic Medical Records: A Review

    PubMed Central

    Sun, Wencheng; Li, Yangyang; Liu, Fang; Fang, Shengqun; Wang, Guoyan

    2018-01-01

    Currently, medical institutes generally use EMR to record patient's condition, including diagnostic information, procedures performed, and treatment results. EMR has been recognized as a valuable resource for large-scale analysis. However, EMR has the characteristics of diversity, incompleteness, redundancy, and privacy, which make it difficult to carry out data mining and analysis directly. Therefore, it is necessary to preprocess the source data in order to improve data quality and improve the data mining results. Different types of data require different processing technologies. Most structured data commonly needs classic preprocessing technologies, including data cleansing, data integration, data transformation, and data reduction. For semistructured or unstructured data, such as medical text, containing more health information, it requires more complex and challenging processing methods. The task of information extraction for medical texts mainly includes NER (named-entity recognition) and RE (relation extraction). This paper focuses on the process of EMR processing and emphatically analyzes the key techniques. In addition, we make an in-depth study on the applications developed based on text mining together with the open challenges and research issues for future work. PMID:29849998

  9. Massive-training support vector regression and Gaussian process for false-positive reduction in computer-aided detection of polyps in CT colonography

    PubMed Central

    Xu, Jian-Wu; Suzuki, Kenji

    2011-01-01

    Purpose: A massive-training artificial neural network (MTANN) has been developed for the reduction of false positives (FPs) in computer-aided detection (CADe) of polyps in CT colonography (CTC). A major limitation of the MTANN is the long training time. To address this issue, the authors investigated the feasibility of two state-of-the-art regression models, namely, support vector regression (SVR) and Gaussian process regression (GPR) models, in the massive-training framework and developed massive-training SVR (MTSVR) and massive-training GPR (MTGPR) for the reduction of FPs in CADe of polyps. Methods: The authors applied SVR and GPR as volume-processing techniques in the distinction of polyps from FP detections in a CTC CADe scheme. Unlike artificial neural networks (ANNs), both SVR and GPR are memory-based methods that store a part of or the entire training data for testing. Therefore, their training is generally fast and they are able to improve the efficiency of the massive-training methodology. Rooted in a maximum margin property, SVR offers excellent generalization ability and robustness to outliers. On the other hand, GPR approaches nonlinear regression from a Bayesian perspective, which produces both the optimal estimated function and the covariance associated with the estimation. Therefore, both SVR and GPR, as the state-of-the-art nonlinear regression models, are able to offer a performance comparable or potentially superior to that of ANN, with highly efficient training. Both MTSVR and MTGPR were trained directly with voxel values from CTC images. A 3D scoring method based on a 3D Gaussian weighting function was applied to the outputs of MTSVR and MTGPR for distinction between polyps and nonpolyps. To test the performance of the proposed models, the authors compared them to the original MTANN in the distinction between actual polyps and various types of FPs in terms of training time reduction and FP reduction performance. The authors’ CTC database consisted of 240 CTC data sets obtained from 120 patients in the supine and prone positions. The training set consisted of 27 patients, 10 of which had 10 polyps. The authors selected 10 nonpolyps (i.e., FP sources) from the training set. These ten polyps and ten nonpolyps were used for training the proposed models. The testing set consisted of 93 patients, including 19 polyps in 7 patients and 86 negative patients with 474 FPs produced by an original CADe scheme. Results: With the MTSVR, the training time was reduced by a factor of 190, while a FP reduction performance [by-polyp sensitivity of 94.7% (18∕19) with 2.5 (230∕93) FPs∕patient] comparable to that of the original MTANN [the same sensitivity with 2.6 (244∕93) FPs∕patient] was achieved. The classification performance in terms of the area under the receiver-operating-characteristic curve value of the MTGPR (0.82) was statistically significantly higher than that of the original MTANN (0.77), with a two-sided p-value of 0.03. The MTGPR yielded a 94.7% (18∕19) by-polyp sensitivity at a FP rate of 2.5 (235∕93) per patient and reduced the training time by a factor of 1.3. Conclusions: Both MTSVR and MTGPR improve the efficiency of the training in the massive-training framework while maintaining a comparable performance. PMID:21626922

  10. Cure-WISE: HETDEX Data Reduction with Astro-WISE

    NASA Astrophysics Data System (ADS)

    Snigula, J. M.; Drory, N.; Fabricius, M.; Landriau, M.; Montesano, F.; Hill, G. J.; Gebhardt, K.; Cornell, M. E.

    2014-05-01

    The Hobby-Eberly Telescope Dark Energy Experiment (HETDEX, Hill et al. 2012b) is a blind spectroscopic survey to map the evolution of dark energy using Lyman-alpha emitting galaxies at redshifts 1.9< ɀ <3.5 as tracers. The survey will use an array of 75 integral field spectrographs called the Visible Integral field Replicable Unit (IFU) Spectrograph (VIRUS, Hill et al. 2012c). The 10m HET (Ramsey et al. 1998) currently receives a wide-field upgrade (Hill et al. 2012a) to accomodate the spectrographs and to provide the needed field of view. Over the projected five year run of the survey we expect to obtain approximately 170 GB of data each night. For the data reduction we developed the Cure pipeline, to automatically find and calibrate the observed spectra, subtract the sky background, and detect and classify different types of sources. Cure employs rigorous statistical methods and complete pixel-level error propagation throughout the reduction process to ensure Poisson-limited performance and meaningful significance values. To automate the reduction of the whole dataset we implemented the Cure pipeline in the Astro-WISE framework. This integration provides for HETDEX a database backend with complete dependency tracking of the various reduction steps, automated checks, and a searchable interface to the detected sources and user management. It can be used to create various web interfaces for data access and quality control. Astro-WISE allows us to reduce the data from all the IFUs in parallel on a compute cluster. This cluster allows us to reduce the observed data in quasi real time and still have excess capacity for rerunning parts of the reduction. Finally, the Astro-WISE interface will be used to provide access to reduced data products to the general community.

  11. Reductive stripping process for the recovery of uranium from wet-process phosphoric acid

    DOEpatents

    Hurst, Fred J.; Crouse, David J.

    1984-01-01

    A reductive stripping flow sheet for recovery of uranium from wet-process phosphoric acid is described. Uranium is stripped from a uranium-loaded organic phase by a redox reaction converting the uranyl to uranous ion. The uranous ion is reoxidized to the uranyl oxidation state to form an aqueous feed solution highly concentrated in uranium. Processing of this feed through a second solvent extraction cycle requires far less stripping reagent as compared to a flow sheet which does not include the reductive stripping reaction.

  12. Efficacy of water treatment processes and endemic gastrointestinal illness - A multi-city study in Sweden.

    PubMed

    Tornevi, Andreas; Simonsson, Magnus; Forsberg, Bertil; Säve-Söderbergh, Melle; Toljander, Jonas

    2016-10-01

    Outbreaks of acute gastrointestinal illnesses (AGI) have been linked to insufficient drinking water treatment on numerous occasions in the industrialized world, but it is largely unknown to what extent public drinking water influences the endemic level of AGI. This paper aimed to examine endemic AGI and the relationship with pathogen elimination efficacy in public drinking water treatment processes. For this reason, time series data of all telephone calls to the Swedish National Healthcare Guide between November 2007 and February 2014 from twenty Swedish cities were obtained. Calls concerning vomiting, diarrhea or abdominal pain (AGI calls) were separated from other concerns (non-AGI calls). Information on which type of microbial barriers each drinking water treatment plant in these cities have been used were obtained, together with the barriers' theoretical pathogen log reduction efficacy. The total log reduction in the drinking water plants varied between 0.0 and 6.1 units for viruses, 0.0-14.6 units for bacteria and 0.0-7.3 units regarding protozoans. To achieve one general efficacy parameter for each plant, a weighted mean value of the log reductions (WLR) was calculated, with the weights based on how commonly these pathogen groups cause AGI. The WLR in the plants varied between 0.0 and 6.4 units. The effect of different pathogen elimination efficacy on levels of AGI calls relative non-AGI calls was evaluated in regression models, controlling for long term trends, population size, age distribution, and climatological area. Populations receiving drinking water produced with higher total log reduction was associated with a lower relative number of AGI calls. In overall, AGI calls decreased by 4% (OR = 0.96, CI: 0.96-0.97) for each unit increase in the WLR. The findings apply to both groundwater and surface water study sites, but are particularly evident among surface water sites during seasons when viruses are the main cause of AGI. This study proposes that the endemic level of gastroenteritis can indeed be reduced with more advanced treatment processes at many municipal drinking water treatment plants. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. Reduction of spiked porcine circovirus during the manufacture of a Vero cell-derived vaccine.

    PubMed

    Lackner, Cornelia; Leydold, Sandra M; Modrof, Jens; Farcet, Maria R; Grillberger, Leopold; Schäfer, Birgit; Anderle, Heinz; Kreil, Thomas R

    2014-04-11

    Porcine circovirus-1 (PCV1) was recently identified as a contaminant in live Rotavirus vaccines, which was likely caused by contaminated porcine trypsin. The event triggered the development of new regulatory guidance on the use of porcine trypsin which shall ensure that cell lines and porcine trypsin in use are free from PCV1. In addition, manufacturing processes of biologicals other than live vaccines include virus clearance steps that may prevent and mitigate any potential virus contamination of product. In this work, artificial spiking of down-scaled models for the manufacturing process of an inactivated pandemic influenza virus vaccine were used to investigate inactivation of PCV1 and the physico-chemically related porcine parvovirus (PPV) by formalin and ultraviolet-C (UV-C) treatment as well as removal by the purification step sucrose gradient ultracentrifugation. A PCV1 infectivity assay, using a real-time PCR infectivity readout was established. The formalin treatment (0.05% for 48h) showed substantial inactivation for both PCV1 and PPV with reduction factors of 3.0log10 and 6.8log10, respectively, whereas UV-C treatment resulted in complete PPV (≥5.9log10) inactivation already at a dose of 13mJ/cm but merely 1.7log10 at 24mJ/cm(2) for PCV1. The UV-C inactivation results with PPV were confirmed using minute virus of mice (MVM), indicating that parvoviruses are far more sensitive to UV-C than PCV1. The sucrose density gradient ultracentrifugation also contributed to PCV1 clearance with a reduction factor of 2log10. The low pH treatment during the production of procine trypsin was investigated and showed effective inactivation for both PCV1 (4.5log10) and PPV (6.4log10). In conclusion, PCV1 in general appears to be more resistant to virus inactivation than PPV. Still, the inactivated pandemic influenza vaccine manufacturing process provides for robust virus reduction, in addition to the already implemented testing for PCV1 to avoid any contaminations. Copyright © 2014 Elsevier Ltd. All rights reserved.

  14. Light-Driven Heterogeneous Reduction of Carbon Dioxide: Photocatalysts and Photoelectrodes

    DOE PAGES

    White, James L.; Baruch, Maor F.; Pander, III, James E.; ...

    2015-10-07

    A thorough review article on work to publication date on the photocatalysis and photoelectrochemistry of CO 2 reduction chemistry. This work also contains an up to date tutorial on photoelectrochemistry in general.

  15. Diesel emission reduction in construction equipment.

    DOT National Transportation Integrated Search

    2014-01-01

    The state of Rhode Island general law : The Diesel Emission Reduction Act : required a pilot project be undertaken to : gain a better understanding of the : impact of this legislative act. : The Rhode Island Department of : Transportation (RIDO...

  16. ORAC-DR -- integral field spectroscopy data reduction

    NASA Astrophysics Data System (ADS)

    Todd, Stephen

    ORAC-DR is a general-purpose automatic data-reduction pipeline environment. This document describes its use to reduce integral field unit (IFU) data collected at the United Kingdom Infrared Telescope (UKIRT) with the UIST instrument.

  17. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Albeverio, Sergio; Chen Kai; Fei Shaoming

    A necessary separability criterion that relates the structures of the total density matrix and its reductions is given. The method used is based on the realignment method [K. Chen and L. A. Wu, Quant. Inf. Comput. 3, 193 (2003)]. The separability criterion naturally generalizes the reduction separability criterion introduced independently in the previous work [M. Horodecki and P. Horodecki, Phys. Rev. A 59, 4206 (1999) and N. J. Cerf, C. Adami, and R. M. Gingrich, Phys. Rev. A 60, 898 (1999)]. In special cases, it recovers the previous reduction criterion and the recent generalized partial transposition criterion [K. Chen andmore » L. A. Wu, Phys. Lett. A 306, 14 (2002)]. The criterion involves only simple matrix manipulations and can therefore be easily applied.« less

  18. The neurobiological link between compassion and love

    PubMed Central

    Esch, Tobias; Stefano, George B.

    2011-01-01

    Summary Love and compassion exert pleasant feelings and rewarding effects. Besides their emotional role and capacity to govern behavior, appetitive motivation, and a general ‘positive state’, even ‘spiritual’ at times, the behaviors shown in love and compassion clearly rely on neurobiological mechanisms and underlying molecular principles. These processes and pathways involve the brain’s limbic motivation and reward circuits, that is, a finely tuned and profound autoregulation. This capacity to self-regulate emotions, approach behaviors and even pair bonding, as well as social contact in general, i.e., love, attachment and compassion, can be highly effective in stress reduction, survival and overall health. Yet, molecular biology is the basis of interpersonal neurobiology, however, there is no answer to the question of what comes first or is more important: It is a cybernetic capacity and complex circuit of autoregulation that is clearly ‘amazing’. PMID:21358615

  19. [Ecological security of wastewater treatment processes: a review].

    PubMed

    Yang, Sai; Hua, Tao

    2013-05-01

    Though the regular indicators of wastewater after treatment can meet the discharge requirements and reuse standards, it doesn't mean the effluent is harmless. From the sustainable point of view, to ensure the ecological and human security, comprehensive toxicity should be considered when discharge standards are set up. In order to improve the ecological security of wastewater treatment processes, toxicity reduction should be considered when selecting and optimizing the treatment processes. This paper reviewed the researches on the ecological security of wastewater treatment processes, with the focus on the purposes of various treatment processes, including the processes for special wastewater treatment, wastewater reuse, and for the safety of receiving waters. Conventional biological treatment combined with advanced oxidation technologies can enhance the toxicity reduction on the base of pollutants removal, which is worthy of further study. For the process aimed at wastewater reuse, the integration of different process units can complement the advantages of both conventional pollutants removal and toxicity reduction. For the process aimed at ecological security of receiving waters, the emphasis should be put on the toxicity reduction optimization of process parameters and process unit selection. Some suggestions for the problems in the current research and future research directions were put forward.

  20. Chemoprevention of colorectal cancer: systematic review and economic evaluation.

    PubMed

    Cooper, K; Squires, H; Carroll, C; Papaioannou, D; Booth, A; Logan, R F; Maguire, C; Hind, D; Tappenden, P

    2010-06-01

    Colorectal cancer (CRC) is the third most common cancer in the UK: incidence increases with age, median age at diagnosis being over 70 years. Approximately 25% of cases occur in individuals with a family history of CRC, including 5% caused by familial adenomatous polyposis (FAP) or hereditary non-polyposis CRC (HNPCC). Most develop from adenomatous polyps arising from the intestine lining. Individuals with these polyps undergo polypectomy and are invited for endoscopic surveillance. Screening via faecal occult blood testing has been rolled out across the UK. To evaluate the clinical effectiveness and cost-effectiveness of drug and micronutrient interventions for the prevention of CRC and/or adenomatous polyps. Interventions considered include: non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin and cyclo-oxygenase-2 (COX-2) inhibitors; folic acid; calcium; vitamin D and antioxidants (including vitamin A, vitamin C, vitamin E, selenium and beta-carotene). Chemoprevention was assessed in the general population, in individuals at increased risk of CRC, and in individuals with FAP or HNPCC. A systematic review identified randomised controlled trials (RCTs) assessing drug and nutritional agents for the prevention of CRC or adenomatous polyps. A separate search identified qualitative studies relating to individuals' views, attitudes and beliefs about chemoprevention. MEDLINE, MEDLINE In-Process & Other Non-Indexed Citations, EMBASE, CINAHL, the Cochrane Database of Systematic Reviews, Cochrane CENTRAL Register of Controlled Trials, DARE, NHS-EED (NHS Economic Evaluation Database), HTA database, Science Citation Index, BIOSIS previews and the Current Controlled Trials research register were searched in June 2008. Data were extracted by one reviewer and checked by a second. The synthesis methods used were systematic review and meta-analysis for RCTs and qualitative framework synthesis for qualitative studies. A health economic model was developed to assess the cost-effectiveness of chemoprevention for two populations with different levels of risk of developing CRC: the general population and an intermediate-risk population. The search identified 44 relevant RCTs and six ongoing studies. A small study of aspirin in FAP patients produced no statistically significant reduction in polyp number but a possible reduction in polyp size. There was a statistically significant 21% reduction in risk of adenoma recurrence [relative risk (RR) 0.79, 95% confidence interval (CI) 0.68 to 0.92] in an analysis of aspirin versus no aspirin in individuals with a history of adenomas or CRC. In the general population, a significant 26% reduction in CRC incidence was demonstrated in studies with a 23-year follow-up (RR 0.74, 95% CI 0.57 to 0.97). Non-aspirin NSAID use in FAP individuals produced a non-statistically significant reduction in adenoma incidence after 4 years of treatment and follow-up and reductions in polyp number and size. In individuals with a history of adenomas there was a statistically significant 34% reduction in adenoma recurrence risk (RR 0.66, 95% CI 0.60 to 0.72) and a statistically significant 55% reduction in advanced adenoma incidence (RR 0.45, 95% CI 0.35 to 0.58). No studies assessed the effect of non-aspirin NSAIDs in the general population. There were no studies of folic acid in individuals with FAP or HNPCC. There was no significant effect of folic acid versus placebo on adenoma recurrence (RR 1.16, 95% CI 0.97 to 1.39) or advanced adenoma incidence in individuals with a history of adenomas. In the general population there was no significant effect of folic acid on risk of CRC (RR 1.13, 95% CI 0.77 to 1.64), although studies were of relatively short duration. Calcium use by FAP patients produced no significant reduction in polyp number or disease progression. In individuals with a history of adenomas there was a statistically significant 18% reduction in risk of adenoma recurrence (RR 0.82, 95% CI 0.69 to 0.98) and a non-significant reduction in risk of advanced adenomas (RR 0.77, 95% CI 0.50 to 1.17). In the general population there was no significant effect of calcium on risk of CRC (RR 1.08, 95% CI 0.87 to 1.34), although studies were of relatively short duration. There were no studies of antioxidant use in individuals with FAP or HNPCC, and in individuals with a history of adenomas no statistically significant differences in relative risk of adenoma recurrence were found. In the general population there was no difference in incidence of CRC (RR 1.00, 95% CI 0.88 to 1.13) with antioxidant use compared with no antioxidant use. Twenty studies reported qualitative findings concerning chemoprevention. People are more likely to use NSAIDs if there is a strong perceived need. Perceptions of risk and benefit also influence decision-making and use. People have fewer concerns about using antioxidants or other supplements, but their perception of the benefits of these agents is less well-defined. The model analysis suggested that the most cost-effective age-range policy in the general population would be to provide chemoprevention to all individuals within the general population from age 50 to 60 years. The use of aspirin in addition to screening within the general population is likely to result in a discounted cost per life-year gained of around 10,000 pounds and a discounted cost per quality-adjusted life-year (QALY) gained of around 23,000 pounds compared with screening alone. In the intermediate-risk group the most economically viable age-range policy would be to provide chemoprevention to individuals following polypectomy aged 61 to 70 years. Calcium is likely to have a discounted cost per QALY gained of around 8000 pounds compared with screening alone. Although aspirin in addition to screening should be more effective and less costly than screening alone, under the current assumptions of benefits to harms of aspirin and calcium, aspirin is expected to be extendedly dominated by calcium. Whilst a number of studies were included in the review, the duration of follow-up was generally insufficient to detect an effect on cancer incidence. Given the uncertainties and ambiguities in the evidence base, the results of the health economic analysis should be interpreted with caution. Aspirin and celecoxib may reduce recurrence of adenomas and incidence of advanced adenomas in individuals with an increased risk of CRC and calcium may reduce recurrence of adenomas in this group. COX-2 inhibitors may decrease polyp number in patients with FAP. There is some evidence for aspirin reducing the incidence of CRC in the general population. Both aspirin and NSAIDs are associated with adverse effects so it will be important to consider the risk-benefit ratio before recommending these agents for chemoprevention. The economic analysis suggests that chemoprevention has the potential to represent a cost-effective intervention, particularly when targeted at intermediate-risk populations following polypectomy.

  1. Pre-treatment Social Anxiety Severity Moderates the Impact of Mindfulness-Based Stress Reduction and Aerobic Exercise

    PubMed Central

    Jazaieri, Hooria; Lee, Ihno A.; Goldin, Philippe R.; Gross, James J.

    2015-01-01

    We examined whether social anxiety severity at pre-treatment would moderate the impact of Mindfulness-Based Stress Reduction (MBSR) or Aerobic Exercise (AE) for generalized social anxiety disorder. MBSR and AE produced equivalent reductions in weekly social anxiety symptoms. Improvements were moderated by pre-treatment social anxiety severity. PMID:25684277

  2. Aircraft Piston Engine Exhaust Emission Symposium

    NASA Technical Reports Server (NTRS)

    1976-01-01

    A 2-day symposium on the reduction of exhaust emissions from aircraft piston engines was held on September 14 and 15, 1976, at the Lewis Research Center in Cleveland, Ohio. Papers were presented by both government organizations and the general aviation industry on the status of government contracts, emission measurement problems, data reduction procedures, flight testing, and emission reduction techniques.

  3. 20 CFR 228.20 - Reduction for an employee annuity.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Reduction for an employee annuity. 228.20... COMPUTATION OF SURVIVOR ANNUITIES The Tier I Annuity Component § 228.20 Reduction for an employee annuity. (a) General. If an individual is entitled to an annuity as a survivor, and is also entitled to an employee...

  4. Optimization of Ozonation Process for the Reduction of Excess Sludge Production from Activated Sludge Process of Sago Industry Wastewater Using Central Composite Design

    PubMed Central

    Subha, B.; Muthukumar, M.

    2012-01-01

    Sago industries effluent containing large amounts of organic content produced excess sludge which is a serious problem in wastewater treatment. In this study ozonation has been employed for the reduction of excess sludge production in activated sludge process. Central composite design is used to study the effect of ozone treatment for the reduction of excess sludge production in sago effluent and to optimise the variables such as pH, ozonation time, and retention time. ANOVA showed that the coefficient determination value (R 2) of VSS and COD reduction were 0.9689 and 0.8838, respectively. VSS reduction (81%) was achieved at acidic pH 6.9, 12 minutes ozonation, and retention time of 10 days. COD reduction (87%) was achieved at acidic pH 6.7, 8 minutes of ozonation time, and retention time of 6 days. Low ozonation time and high retention time influence maximum sludge reduction, whereas low ozonation time with low retention time was effective for COD reduction. PMID:22593666

  5. Preparation of Ferrotitanium from Ilmenite by Electrolysis-Assisted Calciothermic Reduction in CaCl2-NaCl Molten Salt

    NASA Astrophysics Data System (ADS)

    Zhou, Zhongren; Hua, Yixin; Xu, Cunying; Li, Jian; Li, Yan; Gong, Kai; Ru, Juanjian; Xiong, Li

    2016-02-01

    Electrolysis-assisted calciothermic reduction method is proposed and successfully used to prepare ferrotitanium alloy from ilmenite by using equal-molar CaCl2-NaCl molten salt as electrolyte, molybdenum rod as cathode, and graphite as anode at 973 K with cell voltages of 3.2-4.4 V under inert atmosphere. Thermodynamics analysis of the process is presented, and the products obtained are examined with x-ray diffraction, scanning electron microscopy, and energy-dispersive spectroscopy. It is demonstrated that the calciothermic reduction of ilmenite is a stepwise process since intermediate CaTiO3 is observed in the products partially reduced. In the calciothermic reduction process, the reduction of FeTiO3 first gives rise to the formation of Fe and CaTiO3, which as intermediates will further react with calcium metal to form ferrotitanium alloys. This is in good agreement with the prediction of thermodynamics. Experimental results also show that increasing cell voltage can accelerate the formation of calcium metal through electrolysis of CaO and CaCl2 and, hence, promote the calciothermic reduction of ilmenite. As the electrolytic zone and reduction zone are combined in the same bath, the theoretical energy requirement for the production of FeTi in the calciothermic process is lower than that in the aluminothermic process.

  6. Gyro-gauge-independent formulation of the guiding-center reduction to arbitrary order in the Larmor radius

    NASA Astrophysics Data System (ADS)

    de Guillebon, L.; Vittot, M.

    2013-10-01

    Guiding-center reduction is studied using gyro-gauge-independent coordinates. The Lagrangian 1-form of charged particle dynamics is Lie transformed without introducing a gyro-gauge, but using directly the unit vector of the component of the velocity perpendicular to the magnetic field as the coordinate corresponding to Larmor gyration. The reduction is shown to provide a maximal reduction for the Lagrangian and to work for all orders in the Larmor radius, following exactly the same procedure as when working with the standard gauge-dependent coordinate. The gauge-dependence is removed from the coordinate system by using a constrained variable for the gyro-angle. The closed 1-form dθ is replaced by a more general non-closed 1-form, which is equal to dθ in the gauge-dependent case. The gauge vector is replaced by a more general connection in the definition of the gradient, which behaves as a covariant derivative, in perfect agreement with the circle-bundle picture. This explains some results of previous works, whose gauge-independent expressions did not correspond to gauge fixing but did indeed correspond to connection fixing. In addition, some general results are obtained for the guiding-center reduction. The expansion is polynomial in the cotangent of the pitch-angle as an effect of the structure of the Lagrangian, preserved by Lie derivatives. The induction for the reduction is shown to rely on the inversion of a matrix, which is the same for all orders higher than three. It is inverted and explicit induction relations are obtained to go to an arbitrary order in the perturbation expansion. The Hamiltonian and symplectic representations of the guiding-center reduction are recovered, but conditions for the symplectic representation at each order are emphasized.

  7. A survey of analytical methods employed for monitoring of Advanced Oxidation/Reduction Processes for decomposition of selected perfluorinated environmental pollutants.

    PubMed

    Trojanowicz, Marek; Bobrowski, Krzysztof; Szostek, Bogdan; Bojanowska-Czajka, Anna; Szreder, Tomasz; Bartoszewicz, Iwona; Kulisa, Krzysztof

    2018-01-15

    The monitoring of Advanced Oxidation/Reduction Processes (AO/RPs) for the evaluation of the yield and mechanisms of decomposition of perfluorinated compounds (PFCs) is often a more difficult task than their determination in the environmental, biological or food samples with complex matrices. This is mostly due to the formation of hundreds, or even thousands, of both intermediate and final products. The considered AO/RPs, involving free radical reactions, include photolytic and photocatalytic processes, Fenton reactions, sonolysis, ozonation, application of ionizing radiation and several wet oxidation processes. The main attention is paid to the most commonly occurring PFCs in the environment, namely PFOA and PFOS. The most powerful and widely exploited method for this purpose is without a doubt LC/MS/MS, which allows the identification and trace quantitation of all species with detectability and resolution power depending on the particular instrumental configurations. The GC/MS is often employed for the monitoring of volatile fluorocarbons, confirming the formation of radicals in the processes of C‒C and C‒S bonds cleavage. For the direct monitoring of radicals participating in the reactions of PFCs decomposition, the molecular spectrophotometry is employed, especially electron paramagnetic resonance (EPR). The UV/Vis spectrophotometry as a detection method is of special importance in the evaluation of kinetics of radical reactions with the use of pulse radiolysis methods. The most commonly employed for the determination of the yield of mineralization of PFCs is ion-chromatography, but there is also potentiometry with ion-selective electrode and the measurements of general parameters such as Total Organic Carbon and Total Organic Fluoride. The presented review is based on about 100 original papers published in both analytical and environmental journals. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. A MapReduce approach to diminish imbalance parameters for big deoxyribonucleic acid dataset.

    PubMed

    Kamal, Sarwar; Ripon, Shamim Hasnat; Dey, Nilanjan; Ashour, Amira S; Santhi, V

    2016-07-01

    In the age of information superhighway, big data play a significant role in information processing, extractions, retrieving and management. In computational biology, the continuous challenge is to manage the biological data. Data mining techniques are sometimes imperfect for new space and time requirements. Thus, it is critical to process massive amounts of data to retrieve knowledge. The existing software and automated tools to handle big data sets are not sufficient. As a result, an expandable mining technique that enfolds the large storage and processing capability of distributed or parallel processing platforms is essential. In this analysis, a contemporary distributed clustering methodology for imbalance data reduction using k-nearest neighbor (K-NN) classification approach has been introduced. The pivotal objective of this work is to illustrate real training data sets with reduced amount of elements or instances. These reduced amounts of data sets will ensure faster data classification and standard storage management with less sensitivity. However, general data reduction methods cannot manage very big data sets. To minimize these difficulties, a MapReduce-oriented framework is designed using various clusters of automated contents, comprising multiple algorithmic approaches. To test the proposed approach, a real DNA (deoxyribonucleic acid) dataset that consists of 90 million pairs has been used. The proposed model reduces the imbalance data sets from large-scale data sets without loss of its accuracy. The obtained results depict that MapReduce based K-NN classifier provided accurate results for big data of DNA. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  9. Elemental sulfur recovery process

    DOEpatents

    Flytzani-Stephanopoulos, M.; Zhicheng Hu.

    1993-09-07

    An improved catalytic reduction process for the direct recovery of elemental sulfur from various SO[sub 2]-containing industrial gas streams. The catalytic process provides combined high activity and selectivity for the reduction of SO[sub 2] to elemental sulfur product with carbon monoxide or other reducing gases. The reaction of sulfur dioxide and reducing gas takes place over certain catalyst formulations based on cerium oxide. The process is a single-stage, catalytic sulfur recovery process in conjunction with regenerators, such as those used in dry, regenerative flue gas desulfurization or other processes, involving direct reduction of the SO[sub 2] in the regenerator off gas stream to elemental sulfur in the presence of a catalyst. 4 figures.

  10. Elemental sulfur recovery process

    DOEpatents

    Flytzani-Stephanopoulos, Maria; Hu, Zhicheng

    1993-01-01

    An improved catalytic reduction process for the direct recovery of elemental sulfur from various SO.sub.2 -containing industrial gas streams. The catalytic process provides combined high activity and selectivity for the reduction of SO.sub.2 to elemental sulfur product with carbon monoxide or other reducing gases. The reaction of sulfur dioxide and reducing gas takes place over certain catalyst formulations based on cerium oxide. The process is a single-stage, catalytic sulfur recovery process in conjunction with regenerators, such as those used in dry, regenerative flue gas desulfurization or other processes, involving direct reduction of the SO.sub.2 in the regenerator off gas stream to elemental sulfur in the presence of a catalyst.

  11. Survival in a Down Economy: A Budget Reduction Process for Superintendents

    ERIC Educational Resources Information Center

    Davis, E. E.; Coffland, Jack A.

    2010-01-01

    Dramatic reductions in the dollars available for public education require a new and systemic approach to balancing school district budgets. This manual provides numerous examples of successful budget reduction strategies based on a six-step process that has demonstrated its effectiveness in small, medium, and large school districts. Supported by…

  12. Synthesis of submicron silver powder from scrap low-temperature co-fired ceramic an e-waste: Understanding the leaching kinetics and wet chemistry.

    PubMed

    Swain, Basudev; Shin, Dongyoon; Joo, So Yeong; Ahn, Nak Kyoon; Lee, Chan Gi; Yoon, Jin-Ho

    2018-03-01

    The current study focuses on the understanding of leaching kinetics of metal in the LTCC in general and silver leaching in particular along with wet chemical reduction involving silver nanoparticle synthesis. Followed by metal leaching, the silver was selectively precipitated using HCl as AgCl. The precipitated AgCl was dissolved in ammonium hydroxide and reduced to pure silver metal nanopowder (NPs) using hydrazine as a reductant. Polyvinylpyrrolidone (PVP) used as a stabilizer and Polyethylene glycol (PEG) used as reducing reagent as well as stabilizing reagent to control size and shape of the Ag NPs. An in-depth investigation indicated a first-order kinetics model fits well with high accuracy among all possible models. Activation energy required for the first order reaction was 21.242 kJ mol -1 for Silver. PVP and PEG 1% each together provide better size control over silver nanoparticle synthesis using 0.4 M hydrazine as reductant, which provides relatively regular morphology in comparison to their individual application. The investigation revealed that the waste LTCC (an industrial e-waste) can be recycled through the reported process even in industrial scale. The novelty of reported recycling process is simplicity, versatile and eco-efficiency through which waste LTCC recycling can address various issues like; (i) industrial waste disposal (ii) synthesis of silver nanoparticles from waste LTCC (iii) circulate metal economy within a closed loop cycle in the industrial economies where resources are scarce, altogether. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Relation of MAGSAT and Gravity Anomalies to the Main Tectonic Provinces of South America. M.S. Thesis

    NASA Technical Reports Server (NTRS)

    Yuan, D. W.

    1984-01-01

    Magnetic anomalies of the South American continent are generally more positive and variable than the oceanic anomalies. There is better correlation between the magnetic anomalies and the major tectonic elements of the continents than between the anomalies and the main tectonic elements of the adjacent oceanic areas. Oceanic areas generally show no direct correlation to the magnetic anomalies. Precambrian continental shields are mainly more magnetic than continental basins and orogenic belts. Shields differ markedly from major aulacogens which are generally characterized by negative magnetic anomalies and positive gravity anomalies. The Andean orogenic belt shows rather poor correlation with the magnetic anomalies. The magnetic data exhibit instead prominent east-west trends, which although consistent with some tectonic features, may be related to processing noise derived from data reduction procedures to correct for external magnetic field effects. The pattern over the Andes is sufficiently distinct from the generally north trending magnetic anomalies occurring in the adjacent Pacific Ocean to separate effectively the leading edge of the South American Plate from the Nazea Plate. Eastern South America is characterized by magnetic anomalies which commonly extend across the continental margin into the Atlantic Ocean.

  14. Combined Effects of Deforestation and Doubled Atmospheric CO2 Concentrations on the Climate of Amazonia.

    NASA Astrophysics Data System (ADS)

    Costa, Marcos Heil; Foley, Jonathan A.

    2000-01-01

    It is generally expected that the Amazon basin will experience at least two major environmental changes during the next few decades and centuries: 1) increasing areas of forest will be converted to pasture and cropland, and 2) concentrations of atmospheric CO2 will continue to rise. In this study, the authors use the National Center for Atmospheric Research GENESIS atmospheric general circulation model, coupled to the Integrated Biosphere Simulator, to determine the combined effects of large-scale deforestation and increased CO2 concentrations (including both physiological and radiative effects) on Amazonian climate.In these simulations, deforestation decreases basin-average precipitation by 0.73 mm day1 over the basin, as a consequence of the general reduction in vertical motion above the deforested area (although there are some small regions with increased vertical motion). The overall effect of doubled CO2 concentrations in Amazonia is an increase in basin-average precipitation of 0.28 mm day1. The combined effect of deforestation and doubled CO2, including the interactions among the processes, is a decrease in the basin-average precipitation of 0.42 mm day1. While the effects of deforestation and increasing CO2 concentrations on precipitation tend to counteract one another, both processes work to warm the Amazon basin. The effect of deforestation and increasing CO2 concentrations both tend to increase surface temperature, mainly because of decreases in evapotranspiration and the radiative effect of CO2. The combined effect of deforestation and doubled CO2, including the interactions among the processes, increases the basin-average temperature by roughly 3.5°C.

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sridharan, Niyanth; Gussev, Maxim; Seibert, Rachel

    Ultrasonic additive manufacturing (UAM) is a solid-state process, which uses ultrasonic vibrations at 20 kHz along with mechanized tape layering and intermittent milling operation, to build fully functional three-dimensional parts. In the literature, UAM builds made with low power (1.5 kW) exhibited poor tensile properties in Z-direction, i.e., normal to the interfaces. This reduction in properties is often attributed to the lack of bonding at faying interfaces. The generality of this conclusion is evaluated further in 6061 aluminum alloy builds made with very high power UAM (9 kW). Tensile deformation behavior along X and Z directions were evaluated with small-scalemore » in-situ mechanical testing equipped with high-resolution digital image correlation, as well as, multi-scale characterization of builds. Interestingly, even with complete metallurgical bonding across the interfaces without any discernable voids, poor Z-direction properties were observed. This reduction is correlated to coalescence of pre-existing shear bands at interfaces into micro voids, leading to strain localization and spontaneous failure on tensile loading.« less

  16. Harvesting multiple electron-hole pairs generated through plasmonic excitation of Au nanoparticles.

    PubMed

    Kim, Youngsoo; Smith, Jeremy G; Jain, Prashant K

    2018-05-07

    Multi-electron redox reactions, although central to artificial photosynthesis, are kinetically sluggish. Amidst the search for synthetic catalysts for such processes, plasmonic nanoparticles have been found to catalyse multi-electron reduction of CO 2 under visible light. This example motivates the need for a general, insight-driven framework for plasmonic catalysis of such multi-electron chemistry. Here, we elucidate the principles underlying the extraction of multiple redox equivalents from a plasmonic photocatalyst. We measure the kinetics of electron harvesting from a gold nanoparticle photocatalyst as a function of photon flux. Our measurements, supported by theoretical modelling, reveal a regime where two-electron transfer from the excited gold nanoparticle becomes prevalent. Multiple electron harvesting becomes possible under continuous-wave, visible-light excitation of moderate intensity due to strong interband transitions in gold and electron-hole separation accomplished using a hole scavenger. These insights will help expand the utility of plasmonic photocatalysis beyond CO 2 reduction to other challenging multi-electron, multi-proton transformations such as N 2 fixation.

  17. Reducing queues: demand and capacity variations.

    PubMed

    Eriksson, Henrik; Bergbrant, Ing-Marie; Berrum, Ingela; Mörck, Boel

    2011-01-01

    The aim of this paper is to investigate how waiting lists or queues could be reduced without adding more resources; and to describe what factors sustain reduced waiting-times. Cases were selected according to successful and sustained queue reduction. The approach in this study is action research. Accessibility improved as out-patient waiting lists for two clinics were reduced. The main success was working towards matching demand and capacity. It has been possible to sustain the improvements. Results should be viewed cautiously. Transferring and generalizing outcomes from this study is for readers to consider. However, accessible healthcare may be possible by paying more attention to existing solutions. The study indicates that queue reduction activities should include acquiring knowledge about theories and methods to improve accessibility, finding ways to monitor varying demand and capacity, and to improve patient processing by reducing variations. Accessibility is considered an important dimension when measuring service quality. However, there are few articles on how clinic staff sustain reduces waiting lists. This paper contributes accessible knowledge to the field.

  18. Evaluation of space shuttle main engine fluid dynamic frequency response characteristics

    NASA Technical Reports Server (NTRS)

    Gardner, T. G.

    1980-01-01

    In order to determine the POGO stability characteristics of the space shuttle main engine liquid oxygen (LOX) system, the fluid dynamic frequency response functions between elements in the SSME LOX system was evaluated, both analytically and experimentally. For the experimental data evaluation, a software package was written for the Hewlett-Packard 5451C Fourier analyzer. The POGO analysis software is documented and consists of five separate segments. Each segment is stored on the 5451C disc as an individual program and performs its own unique function. Two separate data reduction methods, a signal calibration, coherence or pulser signal based frequency response function blanking, and automatic plotting features are included in the program. The 5451C allows variable parameter transfer from program to program. This feature is used to advantage and requires only minimal user interface during the data reduction process. Experimental results are included and compared with the analytical predictions in order to adjust the general model and arrive at a realistic simulation of the POGO characteristics.

  19. Systematic Sensitivity Analysis of Metabolic Controllers During Reductions in Skeletal Muscle Blood Flow

    NASA Technical Reports Server (NTRS)

    Radhakrishnan, Krishnan; Cabrera, Marco

    2000-01-01

    An acute reduction in oxygen delivery to skeletal muscle is generally associated with profound derangements in substrate metabolism. Given the complexity of the human bioenergetic system and its components, it is difficult to quantify the interaction of cellular metabolic processes to maintain ATP homeostasis during stress (e.g., hypoxia, ischemia, and exercise). Of special interest is the determination of mechanisms relating tissue oxygenation to observed metabolic responses at the tissue, organ, and whole body levels and the quantification of how changes in oxygen availability affect the pathways of ATP synthesis and their regulation. In this study, we apply a previously developed mathematical model of human bioenergetics to study effects of ischemia during periods of increased ATP turnover (e.g., exercise). By using systematic sensitivity analysis the oxidative phosphorylation rate was found to be the most important rate parameter affecting lactate production during ischemia under resting conditions. Here we examine whether mild exercise under ischemic conditions alters the relative importance of pathways and parameters previously obtained.

  20. Examining the effectiveness of a restorative justice program for various types of juvenile offenders.

    PubMed

    Bergseth, Kathleen J; Bouffard, Jeffrey A

    2013-09-01

    Restorative justice (RJ) programs have become widespread in the United States and in other countries. These programs are often seen as a viable alternative to traditional retributive processing, especially for minor, and sometimes more serious, forms of delinquency and adult criminality. The programs hold promise for achieving several goals, including increased community and victim involvement, greater satisfaction with the case outcomes, improved offender compliance, increased perceptions of fairness, and even recidivism reduction. Meta-analyses have demonstrated varying degrees of program success in recidivism reduction, which may in part reflect differential effectiveness of the RJ approach for various kinds of offenders. This study examined whether an RJ program for juvenile offenders had differential impacts on recidivism across various offender characteristics (including age, gender, racial group, offending history, and current offense). Results generally support the effectiveness of the program for many types of offenders. Implications for future research and potential improvements to the RJ model are discussed.

  1. Drastic reduction in the growth temperature of graphene on copper via enhanced London dispersion force

    PubMed Central

    Choi, Jin-Ho; Li, Zhancheng; Cui, Ping; Fan, Xiaodong; Zhang, Hui; Zeng, Changgan; Zhang, Zhenyu

    2013-01-01

    London dispersion force is ubiquitous in nature, and is increasingly recognized to be an important factor in a variety of surface processes. Here we demonstrate unambiguously the decisive role of London dispersion force in non-equilibrium growth of ordered nanostructures on metal substrates using aromatic source molecules. Our first-principles based multi-scale modeling shows that a drastic reduction in the growth temperature, from ~1000°C to ~300°C, can be achieved in graphene growth on Cu(111) when the typical carbon source of methane is replaced by benzene or p-Terphenyl. The London dispersion force enhances their adsorption energies by about (0.5–1.8) eV, thereby preventing their easy desorption, facilitating dehydrogenation, and promoting graphene growth at much lower temperatures. These quantitative predictions are validated in our experimental tests, showing convincing demonstration of monolayer graphene growth using the p-Terphenyl source. The general trends established are also more broadly applicable in molecular synthesis of surface-based nanostructures. PMID:23722566

  2. Automated detection of lung nodules with three-dimensional convolutional neural networks

    NASA Astrophysics Data System (ADS)

    Pérez, Gustavo; Arbeláez, Pablo

    2017-11-01

    Lung cancer is the cancer type with highest mortality rate worldwide. It has been shown that early detection with computer tomography (CT) scans can reduce deaths caused by this disease. Manual detection of cancer nodules is costly and time-consuming. We present a general framework for the detection of nodules in lung CT images. Our method consists of the pre-processing of a patient's CT with filtering and lung extraction from the entire volume using a previously calculated mask for each patient. From the extracted lungs, we perform a candidate generation stage using morphological operations, followed by the training of a three-dimensional convolutional neural network for feature representation and classification of extracted candidates for false positive reduction. We perform experiments on the publicly available LIDC-IDRI dataset. Our candidate extraction approach is effective to produce precise candidates with a recall of 99.6%. In addition, false positive reduction stage manages to successfully classify candidates and increases precision by a factor of 7.000.

  3. Use of MAGSAT anomaly data for crustal structure and mineral resources in the US Midcontinent

    NASA Technical Reports Server (NTRS)

    Carmichael, R. S. (Principal Investigator)

    1981-01-01

    The analysis and preliminary interpretation of investigator-B MAGSAT data are addressed. The data processing included: (1) removal of spurious data points; (2) statistical smoothing along individual data tracks, to reduce the effect of geomagnetic transient disturbances; (3) comparison of data profiles spatially coincident in track location but acquired at different times; (4) reduction of data by weighted averaging to a grid with 1 deg xl deg latitude/longitude spacing, and with elevations interpolated and weighted to a common datum of 400 km; (5) wavelength filtering; and (6) reduction of the anomaly map to the magnetic pole. Agreement was found between a magnitude data anomaly map and a reduce-to-the-pole map supporting the general assumption that, on a large scale (long wavelength), it is induced crustal magnetization which is responsible for major anamalies. Anomalous features are identified and explanations are suggested with regard to crustal structure, petrologic characteristics, and Curie temperature isotherms.

  4. Gravity measurement, processing and evaluation: Test cases de Peel and South Limburg

    NASA Astrophysics Data System (ADS)

    Nohlmans, Ron

    1990-05-01

    A general overview of the process of the measurement and the adjustment of a gravity network and the computation of some output parameters of gravimetry, gravity values, gravity anomalies and mean block anomalies, is given. An overview of developments in gravimetry, globally and in the Netherlands, until now is given. The basic theory of relative gravity measurements is studied and a description of the most commonly used instrument, the LaCoste and Romberg gravimeter is given. The surveys done in the scope of this study are descibed. A more detailed impression of the adjustment procedure and the results of the adjustment are given. A closer look is taken at the more geophysical side of gravimetry: gravity reduction, the computation of anomalies and the correlation with elevation. The interpolation of gravity and the covariance of gravity anomalies are addressed.

  5. Breast feeding after reduction mammaplasty performed during adolescence.

    PubMed

    Aillet, S; Watier, E; Chevrier, S; Pailheret, J-P; Grall, J-Y

    2002-02-10

    Reduction mammaplasty (RM) can be performed during adolescence if the functional capacity of the breast is preserved. Future breast feeding must be carefully considered in the therapeutic decision making process. Breast feeding after reduction mammaplasty performed during adolescence was assessed to determine surgical factors influencing outcome and patient reception of information concerning breast feeding. A questionnaire was sent to 109 women who had undergone reduction mammaplasty between 1981 and 1997 when they were 15-17 years old to ascertain their reasons for having surgery, their satisfaction, and their attitude towards breast feeding. Sixty-five questionnaires (60%) could be analyzed. Mean delay since surgery was 8.1 years. Seventeen women (26%) had delivered 25 infants (mean 1.5). Mean delay after surgery to first delivery was 7.68 years. Five women (29%) nursed their first infant for a mean 11.3 days. None of the women interrupted breast feeding for a reason related to a nipple anomaly or difficult sucking. Twelve women (71%) did not nurse their first infant, because of the prior breast surgery for six of them. Among the 48 nulliparous women, 24 (50%) stated they would nurse their future infant. Although information on breast feeding was systematically delivered, 41 women (63%) stated they had not been informed. There was no statistical relationship between breast feeding and degree of satisfaction, patient-assessed scar quality, or nipple disorders. Adolescents who undergo reduction mammaplasty can nurse their future infants with a complication rate similar to that in the general population. Special attention must be given to delivery of information on breast feeding.

  6. Photosensitized H2 Production Using a Zinc Porphyrin-Substituted Protein, Platinum Nanoparticles, and Ascorbate with No Electron Relay: Participation of Good's Buffers.

    PubMed

    Clark, Emily R; Kurtz, Donald M

    2017-04-17

    Development of efficient light-driven splitting of water, 2H 2 O → 2H 2 + O 2 , often attempts to optimize photosensitization of the reductive and oxidative half-reactions individually. Numerous homogeneous and heterogeneous systems have been developed for photochemical stimulation of the reductive half reaction, 2H + + 2e - → H 2 . These systems generally consist of various combinations of a H + reduction catalyst, a photosensitizer (PS), and a "sacrificial" electron donor. Zinc(II)-porphyrins (ZnPs) have frequently been used as PSs for H 2 generation, but they are subject to various self-quenching processes in aqueous solutions. Colloidal platinum in nanoparticle form (Pt NP) is a classical H + reduction catalyst using ZnP photosensitizers, but efficient photosensitized H 2 generation requires an electron relay molecule between ZnP and Pt NP. The present report describes an aqueous system for visible (white) light-sensitized generation of H 2 using a protein-embedded Zn(II)-protoporphyrin IX as PS and Pt NP as H + reduction catalyst without an added electron relay. This system operated efficiently in piperazino- and morpholino-alkylsulfonic acid (Good's buffers), which served as sacrificial electron donors. The system also required ascorbate at relatively modest concentrations, which stabilized the Zn(II)-protoporphyrin IX against photodegradation. In the absence of an electron relay molecule, the photosensitized H 2 generation must involve formation of at least a transient complex between a protein-embedded Zn(II)-protoporphyrin IX species and Pt NP.

  7. Molten salt applications in materials processing

    NASA Astrophysics Data System (ADS)

    Mishra, Brajendra; Olson, David L.

    2005-02-01

    The science of molten salt electrochemistry for electrowinning of reactive metals, such as calcium, and its in situ application in pyro-reduction has been described. Calcium electrowinning has been performed in a 5 10 wt% calcium oxide calcium chloride molten salt by the electrolytic dissociation of calcium oxide. This electrolysis requires the use of a porous ceramic sheath around the anode to keep the cathodically deposited calcium and the anodic gases separate. Stainless steel cathode and graphite anode have been used in the temperature range of 850 950 °C. This salt mixture is produced as a result of the direct oxide reduction (DOR) of reactive metal oxides by calcium in a calcium chloride bath. The primary purpose of this process is to recover the expensive calcium reductant and to recycle calcium chloride. Experimental data have been included to justify the suitability as well as limitations of the electrowinning process. Transport of oxygen ions through the sheath is found to be the rate controlling step. Under the constraints of the reactor design, a calcium recovery rate of approx. 150 g/h was achieved. Feasibility of a process to produce metals by pyrometallurgical reduction, using the calcium reductant produced electrolytically within the same reactor, has been shown in a hybrid process. Several processes are currently under investigation to use this electrowon calcium for in situ reduction of metal oxides.

  8. 36 CFR 218.3 - Authorized hazardous fuel reduction projects subject to objection.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... SERVICE, DEPARTMENT OF AGRICULTURE PREDECISIONAL ADMINISTRATIVE REVIEW PROCESSES Predecisional Administrative Review Process for Hazardous Fuel Reduction Projects Authorized by the Healthy Forests Restoration..., the objection process of this part applies to both the plan amendment and the project. ...

  9. Evaluation of a controlled drinking minimal intervention for problem drinkers in general practice (the DRAMS scheme)

    PubMed Central

    Heather, Nick; Campion, Peter D.; Neville, Ronald G.; Maccabe, David

    1987-01-01

    Sixteen general practitioners participated in a controlled trial of the Scottish Health Education Group's DRAMS (drinking reasonably and moderately with self-control) scheme. The scheme was evaluated by randomly assigning 104 heavy or problem drinkers to three groups – a group participating in the DRAMS scheme (n = 34), a group given simple advice only (n = 32) and a non-intervention control group (n = 38). Six month follow-up information was obtained for 91 subjects (87.5% of initial sample). There were no significant differences between the groups in reduction in alcohol consumption, but patients in the DRAMS group showed a significantly greater reduction in a logarithmic measure of serum gamma-glutamyl-transpeptidase than patients in the group receiving advice only. Only 14 patients in the DRAMS group completed the full DRAMS procedure. For the sample as a whole, there was a significant reduction in alcohol consumption, a significant improvement on a measure of physical health and well-being, and significant reductions in the logarithmic measure of serum gamma-glutamyl transpeptidase and in mean corpuscular volume. The implications of these findings for future research into controlled drinking minimal interventions in general practice are discussed. PMID:3448228

  10. 36 CFR 218.12 - Timing of authorized hazardous fuel reduction project decision.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... SERVICE, DEPARTMENT OF AGRICULTURE PREDECISIONAL ADMINISTRATIVE REVIEW PROCESSES Predecisional Administrative Review Process for Hazardous Fuel Reduction Projects Authorized by the Healthy Forests Restoration...

  11. Evaluation of selected chemical processes for production of low-cost silicon. Quarterly progress report, 15 Dec 1975--31 Mar 1976

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blocher, J.M. Jr; Browning, M.F.; Wilson, W.J.

    1976-04-08

    Plant construction costs and manufacturing costs were estimmated for the production of solar-grade silicon by the reduction of silicon tetrachloride in a fluidized bed of seed particles, and several modifications of the iodide process using either thermal decomposition on heated filaments (rods) or hydrogen reduction in a fluidized bed of seed particles. Energy consumption data for the zinc reduction process and each of the iodide process options are given and all appear to be acceptable from the standpoint of energy pay back. Information is presented on the experimental zinc reduction of SiCl4 and electrolytic recovery of zinc from ZnCl2. Allmore » of the experimental work performed thus far has supported the initial assumption as to technical feasibility of producing semiconductor silicon by the zinc reduction or iodide processes proposed. The results of a more thorough thermodynamic evaluation of the iodination of silicon oxide/carbon mixtures are presented which explain apparent inconsistencies in an earlier cursory examination of the system.« less

  12. Determining the energetic and informational components of speech-on-speech masking

    PubMed Central

    Kidd, Gerald; Mason, Christine R.; Swaminathan, Jayaganesh; Roverud, Elin; Clayton, Kameron K.; Best, Virginia

    2016-01-01

    Identification of target speech was studied under masked conditions consisting of two or four independent speech maskers. In the reference conditions, the maskers were colocated with the target, the masker talkers were the same sex as the target, and the masker speech was intelligible. The comparison conditions, intended to provide release from masking, included different-sex target and masker talkers, time-reversal of the masker speech, and spatial separation of the maskers from the target. Significant release from masking was found for all comparison conditions. To determine whether these reductions in masking could be attributed to differences in energetic masking, ideal time-frequency segregation (ITFS) processing was applied so that the time-frequency units where the masker energy dominated the target energy were removed. The remaining target-dominated “glimpses” were reassembled as the stimulus. Speech reception thresholds measured using these resynthesized ITFS-processed stimuli were the same for the reference and comparison conditions supporting the conclusion that the amount of energetic masking across conditions was the same. These results indicated that the large release from masking found under all comparison conditions was due primarily to a reduction in informational masking. Furthermore, the large individual differences observed generally were correlated across the three masking release conditions. PMID:27475139

  13. Multiscale model reduction for shale gas transport in poroelastic fractured media

    NASA Astrophysics Data System (ADS)

    Akkutlu, I. Yucel; Efendiev, Yalchin; Vasilyeva, Maria; Wang, Yuhe

    2018-01-01

    Inherently coupled flow and geomechanics processes in fractured shale media have implications for shale gas production. The system involves highly complex geo-textures comprised of a heterogeneous anisotropic fracture network spatially embedded in an ultra-tight matrix. In addition, nonlinearities due to viscous flow, diffusion, and desorption in the matrix and high velocity gas flow in the fractures complicates the transport. In this paper, we develop a multiscale model reduction approach to couple gas flow and geomechanics in fractured shale media. A Discrete Fracture Model (DFM) is used to treat the complex network of fractures on a fine grid. The coupled flow and geomechanics equations are solved using a fixed stress-splitting scheme by solving the pressure equation using a continuous Galerkin method and the displacement equation using an interior penalty discontinuous Galerkin method. We develop a coarse grid approximation and coupling using the Generalized Multiscale Finite Element Method (GMsFEM). GMsFEM constructs the multiscale basis functions in a systematic way to capture the fracture networks and their interactions with the shale matrix. Numerical results and an error analysis is provided showing that the proposed approach accurately captures the coupled process using a few multiscale basis functions, i.e. a small fraction of the degrees of freedom of the fine-scale problem.

  14. Digital Signal Processing For Low Bit Rate TV Image Codecs

    NASA Astrophysics Data System (ADS)

    Rao, K. R.

    1987-06-01

    In view of the 56 KBPS digital switched network services and the ISDN, low bit rate codecs for providing real time full motion color video are under various stages of development. Some companies have already brought the codecs into the market. They are being used by industry and some Federal Agencies for video teleconferencing. In general, these codecs have various features such as multiplexing audio and data, high resolution graphics, encryption, error detection and correction, self diagnostics, freezeframe, split video, text overlay etc. To transmit the original color video on a 56 KBPS network requires bit rate reduction of the order of 1400:1. Such a large scale bandwidth compression can be realized only by implementing a number of sophisticated,digital signal processing techniques. This paper provides an overview of such techniques and outlines the newer concepts that are being investigated. Before resorting to the data compression techniques, various preprocessing operations such as noise filtering, composite-component transformation and horizontal and vertical blanking interval removal are to be implemented. Invariably spatio-temporal subsampling is achieved by appropriate filtering. Transform and/or prediction coupled with motion estimation and strengthened by adaptive features are some of the tools in the arsenal of the data reduction methods. Other essential blocks in the system are quantizer, bit allocation, buffer, multiplexer, channel coding etc.

  15. Within-session effect of repeated stress exposure on extinction circuitry function in social anxiety disorder.

    PubMed

    Åhs, Fredrik; Gingnell, Malin; Furmark, Tomas; Fredrikson, Mats

    2017-03-30

    Anxiety reduction following repeated exposure to stressful experiences is generally held to depend on neural processes involved in extinction of conditioned fear. We predicted that repeated exposure to stressful experiences would change activity throughout the circuitry serving extinction, including ventromedial prefrontal cortex (vmPFC), the hippocampus and the amygdala. To test this prediction, 36 participants diagnosed with SAD performed two successive speeches in front of an observing audience while regional cerebral blood flow (rCBF) was recorded using positron emission tomography. To control for non-anxiolytic effects of repeated exposure, rCBF was also measured during repeated presentations of neutral and angry facial expressions. Results showed that anxiety ratings and heart rate decreased from the first to the second speech, indicating an anxiolytic effect of repeated exposure. Exposure attenuated rCBF in the amygdala whereas no change in rCBF was observed in the vmPFC or hippocampus. The rCBF-reductions in the amygdala were greater following repetition of the speech task than repetition of face exposure indicating that they were specific to anxiety attenuation and not due to a reduced novelty. Our findings suggest that amygdala-related attenuation processes are key to understanding the working mechanisms of exposure therapy. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  16. Using standardized patients to evaluate hospital-based intervention outcomes.

    PubMed

    Li, Li; Lin, Chunqing; Guan, Jihui

    2014-06-01

    The standardized patient approach has proved to be an effective training tool for medical educators. This article explains the process of employing standardized patients in an HIV stigma reduction intervention in healthcare settings in China. The study was conducted in 40 hospitals in two provinces of China. One year after the stigma reduction intervention, standardized patients made unannounced visits to participating hospitals, randomly approached service providers on duty and presented symptoms related to HIV and disclosed HIV-positive test results. After each visit, the standardized patients evaluated their providers' attitudes and behaviours using a structured checklist. Standardized patients also took open-ended observation notes about their experience and the evaluation process. Seven standardized patients conducted a total of 217 assessments (108 from 20 hospitals in the intervention condition; 109 from 20 hospitals in the control condition). Based on a comparative analysis, the intervention hospitals received a better rating than the control hospitals in terms of general impression and universal precaution compliance as well as a lower score on stigmatizing attitudes and behaviours toward the standardized patients. Standardized patients are a useful supplement to traditional self-report assessments, particularly for measuring intervention outcomes that are sensitive or prone to social desirability. Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2013; all rights reserved.

  17. A daily process examination of episode-specific drinking to cope motivation among college students.

    PubMed

    Ehrenberg, Ethan; Armeli, Stephen; Howland, Maryhope; Tennen, Howard

    2016-06-01

    Theory suggests that state- and trait-like factors should interact in predicting drinking to cope (DTC) motivation, yet no research to date has demonstrated this at the drinking episode level of analysis. Thus, we examined whether daily variation in positive and negative affect and avoidance and active coping were associated with DTC motivation during discrete drinking episodes and whether these associations were moderated by tension-reduction expectancies and other person-level risk factors. Using a secure website, 722 college student drinkers completed a one-time survey regarding their tension reduction expectancies and then reported daily for 30 days on their affect, coping strategies, drinking behaviors and motives for drinking. Individuals reported higher levels of DTC motivation on days when negative affect and avoidance coping were high and positive affect was low. We found only little support for the predicted interactive effects among the day- and person-level predictors. Our results support the state and trait conceptualizations of DTC motivation and provide evidence for the antecedent roles of proximal levels of daily affect and avoidance coping. Our inconsistent results for interaction effects including day-level antecedents raise the possibility that some of these synergistic processes might not generalize across level of analysis. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. A Daily Process Examination of Episode-Specific Drinking to Cope Motivation among College Students

    PubMed Central

    HOWLAND, MARYHOPE; TENNEN, HOWARD

    2016-01-01

    Objective Theory suggests that state- and trait-like factors should interact in predicting drinking to cope (DTC) motivation, yet no research to date has demonstrated this at the drinking episode level of analysis. Thus, we examined whether daily variation in positive and negative affect and avoidance and active coping were associated with DTC motivation during discrete drinking episodes and whether these associations were moderated by tension-reduction expectancies and other person-level risk factors. Methods Using a secure website, 722 college student drinkers completed a one-time survey regarding their tension reduction expectancies and then reported daily for 30 days on their affect, coping strategies, drinking behaviors and motives for drinking. Results Individuals reported higher levels of DTC motivation on days when negative affect and avoidance coping were high and positive affect was low. We found only little support for the predicted interactive effects among the day- and person-level predictors. Conclusion Our results support the state and trait conceptualizations of DTC motivation and provide evidence for the antecedent roles of proximal levels of daily affect and avoidance coping. Our inconsistent results for interaction effects including day-level antecedents raises the possibility that some of these synergistic processes might not generalize across level of analysis. PMID:26894551

  19. Cognitive strategies in the mental rotation task revealed by EEG spectral power.

    PubMed

    Gardony, Aaron L; Eddy, Marianna D; Brunyé, Tad T; Taylor, Holly A

    2017-11-01

    The classic mental rotation task (MRT; Shepard & Metzler, 1971) is commonly thought to measure mental rotation, a cognitive process involving covert simulation of motor rotation. Yet much research suggests that the MRT recruits both motor simulation and other analytic cognitive strategies that depend on visuospatial representation and visual working memory (WM). In the present study, we investigated cognitive strategies in the MRT using time-frequency analysis of EEG and independent component analysis. We scrutinized sensorimotor mu (µ) power reduction, associated with motor simulation, parietal alpha (pα) power reduction, associated with visuospatial representation, and frontal midline theta (fmθ) power enhancement, associated with WM maintenance and manipulation. µ power increased concomitant with increasing task difficulty, suggesting reduced use of motor simulation, while pα decreased and fmθ power increased, suggesting heightened use of visuospatial representation processing and WM, respectively. These findings suggest that MRT performance involves flexibly trading off between cognitive strategies, namely a motor simulation-based mental rotation strategy and WM-intensive analytic strategies based on task difficulty. Flexible cognitive strategy use may be a domain-general cognitive principle that underlies aptitude and spatial intelligence in a variety of cognitive domains. We close with discussion of the present study's implications as well as future directions. Published by Elsevier Inc.

  20. Single-crystalline MFe(2)O(4) nanotubes/nanorings synthesized by thermal transformation process for biological applications.

    PubMed

    Fan, Hai-Ming; Yi, Jia-Bao; Yang, Yi; Kho, Kiang-Wei; Tan, Hui-Ru; Shen, Ze-Xiang; Ding, Jun; Sun, Xiao-Wei; Olivo, Malini Carolene; Feng, Yuan-Ping

    2009-09-22

    We report a general thermal transformation approach to synthesize single-crystalline magnetic transition metal oxides nanotubes/nanorings including magnetite Fe(3)O(4), maghematite gamma-Fe(2)O(3), and ferrites MFe(2)O(4) (M = Co, Mn, Ni, Cu) using hematite alpha-Fe(2)O(3) nanotubes/nanorings template. While the straightforward reduction or reduction-oxides process was employed to produce Fe(3)O(4) and gamma-Fe(2)O(3), the alpha-Fe(2)O(3)/M(OH)(2) core/shell nanostructure was used as precursor to prepare MFe(2)O(4) nanotubes via MFe(2)O(4-x) (0 < x < 1) intermediate. The transformed ferrites nanocrystals retain the hollow structure and single-crystalline nature of the original templates. However, the crystallographic orientation-relationships of cubic spinel ferrites and trigonal hematite show strong correlation with their morpologies. The hollow-structured MFe(2)O(4) nanocrystals with tunable size, shape, and composition have exhibited unique magnetic properties. Moreover, they have been demonstrated as a highly effective peroxidase mimic catalysts for laboratory immunoassays or as a universal nanocapsules hybridized with luminescent QDs for magnetic separation and optical probe of lung cancer cells, suggesting that these biocompatible magnetic nanotubes/nanorings have great potential in biomedicine and biomagnetic applications.

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