reference shear stress: Topics by Science.gov

Sample records for reference shear stress

Variation in the reference Shields stress for bed load transport in gravel‐bed streams and rivers

USGS Publications Warehouse

Mueller, Erich R.; Pitlick, John; Nelson, Jonathan M.

2005-01-01

The present study examines variations in the reference shear stress for bed load transport (τr) using coupled measurements of flow and bed load transport in 45 gravel‐bed streams and rivers. The study streams encompass a wide range in bank‐full discharge (1–2600 m3/s), average channel gradient (0.0003–0.05), and median surface grain size (0.027–0.21 m). A bed load transport relation was formed for each site by plotting individual values of the dimensionless transport rate W* versus the reach‐average dimensionless shear stress τ*. The reference dimensionless shear stress τ*r was then estimated by selecting the value of τ* corresponding to a reference transport rate of W* = 0.002. The results indicate that the discharge corresponding to τ*r averages 67% of the bank‐full discharge, with the variation independent of reach‐scale morphologic and sediment properties. However, values of τ*r increase systematically with average channel gradient, ranging from 0.025–0.035 at sites with slopes of 0.001–0.006 to values greater than 0.10 at sites with slopes greater than 0.02. A corresponding relation for the bank‐full dimensionless shear stress τ*bf, formulated with data from 159 sites in North America and England, mirrors the relation between τ*r and channel gradient, suggesting that the bank‐full channel geometry of gravel‐ and cobble‐bedded streams is adjusted to a relatively constant excess shear stress, τ*bf − τ*r, across a wide range of slopes.
Shear modulus of porcine coronary artery in reference to a new strain measure.

PubMed

Zhang, Wei; Lu, Xiao; Kassab, Ghassan S

2007-11-01

To simplify the stress-strain relationship of blood vessels, we define a logarithmic-exponential (log-exp) strain measure to absorb the nonlinearity. As a result, the constitutive relation between the second Piola-Kirchhoff stress and the log-exp strain can be written as a generalized Hooke's law. In this work, the shear modulus of porcine coronary arteries is determined from the experimental data in inflation-stretch-torsion tests. It is found that the shear modulus with respect to the log-exp strain can be viewed as a material constant in the full range of elasticity, and the incremental shear modulus for Cauchy shear stress and small shear strain at various loading levels can be predicted by the proposed Hooke's law. This result further validates the linear constitutive relation for blood vessels when shear deformation is involved.
Deformation measurements of composite multi-span beam shear specimens by Moire interferometry

NASA Technical Reports Server (NTRS)

Post, D.; Czarnek, R.; Joh, D.; Wood, J.

1984-01-01

Experimental analyses were performed for determination of in plane deformations and shear strains in unidirectional and quasi-isotropic graphite-epoxy beams. Forty-eight ply beams were subjected to 5 point and 3 point flexure. Whole field measurements were recorded at load levels from about 20% to more than 90% of failure loads. Contour maps of U and W displacement fields were obtained by moire interferometry, using reference gratings of 2400 lines/mm. Clearly defined fringes with fringe orders exceeding 1000 were obtained. Whole field contour maps of shear strains were obtained by a method developed for these tests. Various anomalous effects were detected in the displacement fields. Their analysis indicated excess shear strains in resin rich zones in regions of shear tractions; free edge shear strains in quasi-isotropic specimens in regions of normal stresses; and shear stresses associated with cyclic shear compliances of quasi-isotropic plies in regions of shear tractions. Their contributions could occur independently or in superposition. Qualitative analyses addressed questions of relaxation; influence of contact stress distribution; specimen failure; effect of specimen overhang; nonlinearity; and qualities of 5 and 3 point flexure tests.
The Reynolds-stress tensor in diffusion flames; An experimental and theoretical investigation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schneider, F.; Janicka, J.

1990-07-01

The authors present measurements and predictions of Reynolds-stress components and mean velocities in a CH{sub 4}-air diffusion flame. A reference beam LDA technique is applied for measuring all Reynolds-stress components. A hologram with dichromated gelatine as recording medium generates strictly coherent reference beams. The theoretical part describes a Reynolds-stress model based on Favre-averaged quantities, paying special attention to modeling the pressure-shear correlation and the dissipation equation in flames. Finally, measurement/prediction comparisons are presented.
Estimation of in-situ stresses in concrete members using polarized ultrasonic shear waves

NASA Astrophysics Data System (ADS)

Chen, Andrew; Schumacher, Thomas

2014-02-01

Ultrasonic testing is commonly used to detect flaws, estimate geometries, and characterize properties of materials and structures. Acoustoelasticity refers to the dependency of stress wave velocity with applied stresses and is a phenomenon that has been known by geophysicists since the 1960s. A way to capitalize on this effect for concrete applications is by using ultrasonic shear waves which are particularly sensitive to applied stresses when polarized in the direction of the applied stress. The authors conducted an experiment on a 150 mm (6 in.) diameter concrete cylinder specimen with a length of 305 mm (12 in.) that was loaded in discrete load steps to failure. At each load step two ultrasonic shear waves were transmitted through the specimen, one with the polarization perpendicular and the other transverse to the applied stress. The velocity difference between the two sets of polarized shear waves was found to correlate with the applied stress in the specimen. Two potential applications for this methodology include estimation of stresses in pre-stressed concrete bridge girders and investigation of load redistribution in structural support elements after extreme events. This paper introduces the background of the methodology, presents an analysis of the collected data, and discusses the relationship between the recorded signals and the applied stress.
Micromechanical processes of frictional aging and the affect of shear stress on fault healing: insights from material characterization and ultrasonic velocity measurements

NASA Astrophysics Data System (ADS)

Ryan, K. L.; Marone, C.

2015-12-01

During the seismic cycle, faults repeatedly fail and regain strength. The gradual strength recovery is often referred to as frictional healing, and existing works suggest that healing can play an important role in determining the mode of fault slip ranging from dynamic rupture to slow earthquakes. Laboratory studies can play an important role in identifying the processes of frictional healing and their evolution with shear strain during the seismic cycle. These studies also provide data for laboratory-derived friction constitutive laws, which can improve dynamic earthquake models. Previous work shows that frictional healing varies with shear stress on a fault during the interseismic period. Unfortunately, the micromechanical processes that cause shear stress dependent frictional healing are not well understood and cannot be incorporated into current earthquake models. In fault gouge, frictional healing involves compaction and particle rearrangement within sheared granular layers. Therefore, to address these issues, we investigate the role grain size reduction plays in frictional re-strengthening processes at different levels of shear stress. Sample material was preserved from biaxial deformation experiments on granular Westerly granite. The normal stress was held constant at 25 MPa and we performed several 100 second slide-hold-slide tests in each experiment. We conducted a series of 5 experiments each with a different value of normalized shear stress (ranging from 0 to 1), defined as the ratio of the pre-hold shear stress to the shear stress during the hold. The particle size distribution for each sample was analyzed. In addition, acoustic measurements were recorded throughout our experiments to investigate variations in ultrasonic velocity and signal amplitude that reflect changes in the elastic moduli of the layer. Acoustic monitoring provides information about healing mechanisms and can provide a link between laboratory studies and tectonic fault zones.
Estimates of bottom roughness length and bottom shear stress in South San Francisco Bay, California

USGS Publications Warehouse

Cheng, R.T.; Ling, C.-H.; Gartner, J.W.; Wang, P.-F.

1999-01-01

A field investigation of the hydrodynamics and the resuspension and transport of participate matter in a bottom boundary layer was carried out in South San Francisco Bay (South Bay), California, during March-April 1995. Using broadband acoustic Doppler current profilers, detailed measurements of turbulent mean velocity distribution within 1.5 m above bed have been obtained. A global method of data analysis was used for estimating bottom roughness length zo and bottom shear stress (or friction velocities u*). Field data have been examined by dividing the time series of velocity profiles into 24-hour periods and independently analyzing the velocity profile time series by flooding and ebbing periods. The global method of solution gives consistent properties of bottom roughness length zo and bottom shear stress values (or friction velocities u*) in South Bay. Estimated mean values of zo and u* for flooding and ebbing cycles are different. The differences in mean zo and u* are shown to be caused by tidal current flood-ebb inequality, rather than the flooding or ebbing of tidal currents. The bed shear stress correlates well with a reference velocity; the slope of the correlation defines a drag coefficient. Forty-three days of field data in South Bay show two regimes of zo (and drag coefficient) as a function of a reference velocity. When the mean velocity is >25-30 cm s-1, the ln zo (and thus the drag coefficient) is inversely proportional to the reference velocity. The cause for the reduction of roughness length is hypothesized as sediment erosion due to intensifying tidal currents thereby reducing bed roughness. When the mean velocity is <25-30 cm s-1, the correlation between zo and the reference velocity is less clear. A plausible explanation of scattered values of zo under this condition may be sediment deposition. Measured sediment data were inadequate to support this hypothesis, but the proposed hypothesis warrants further field investigation.
Orbitally shaken shallow fluid layers. II. An improved wall shear stress model

NASA Astrophysics Data System (ADS)

Alpresa, Paola; Sherwin, Spencer; Weinberg, Peter; van Reeuwijk, Maarten

2018-03-01

A new model for the analytical prediction of wall shear stress distributions at the base of orbitally shaken shallow fluid layers is developed. This model is a generalisation of the classical extended Stokes solution and will be referred to as the potential theory-Stokes model. The model is validated using a large set of numerical simulations covering a wide range of flow regimes representative of those used in laboratory experiments. It is demonstrated that the model is in much better agreement with the simulation data than the classical Stokes solution, improving the prediction in 63% of the studied cases. The central assumption of the model—which is to link the wall shear stress with the surface velocity—is shown to hold remarkably well over all regimes covered.
The shear fracture toughness, KIIc, of graphite

DOE PAGES

Burchell, Timothy D.; Erdman, III, Donald L.

2015-11-05

In this study, the critical shear stress intensity factor, KIIc, here-in referred to as the shear fracture toughness, KIIc (MPa m), of two grades of graphite are reported. The range of specimen volumes was selected to elucidate any specimen size effect, but smaller volume specimen tests were largely unsuccessful, shear failure did not occur between the notches as expected. This was probably due to the specimen geometry causing the shear fracture stress to exceed the compressive failure stress. In subsequent testing the specimen geometry was altered to reduce the compressive footprint and the notches (slits) made deeper to reduce themore » specimen's ligament length. Additionally, we added the collection of Acoustic Emission (AE) during testing to assist with the identification of the shear fracture load. The means of KIIc from large specimens for PCEA and NBG-18 are 2.26 MPa m with an SD of 0.37 MPa m and 2.20 MPa m with an SD of 0.53 MPa m, respectively. The value of KIIc for both graphite grades was similar, although the scatter was large. In this work we found the ratio of KIIc/ KIc ≈ 1.6. .« less
Nonlinear Finite Element Analysis of a General Composite Shell

DTIC Science & Technology

1988-12-01

strain I Poisson’s ratio ix I I iI I I 1 Total potential energy a Normal stress rShear stress Rotational terms Distance from midsurface e ,Y ,0 Rotations...respectively 0 0 Subscript "e" indicates element reference Subscript "g" indicates global reference Superscript "o" indicates midsurface values...surface strains and rotations are small, and displacements away from the midsurface are restricted by the Kirchhoff-Love hypotheses [3]. With these
Use of the Thin-Walled Torsion Specimen

DTIC Science & Technology

1992-08-01

similar to the 316 stainless steel but the shear, stress shows a region of lower 16 strain hardening during the reversal. This behavor has been observed...oscillations and match the axial stress seen in experiment. Among these proposals are: the use of the Green -Naghdi stress rate,22 and the formulation of...other references on the topic. In this section, calculations using Jaumann, Green -Naghdi, and plastic spin motivated stress rates ap- plied to
Time-Resolved Particle Image Velocimetry Measurements with Wall Shear Stress and Uncertainty Quantification for the FDA Nozzle Model.

PubMed

Raben, Jaime S; Hariharan, Prasanna; Robinson, Ronald; Malinauskas, Richard; Vlachos, Pavlos P

2016-03-01

We present advanced particle image velocimetry (PIV) processing, post-processing, and uncertainty estimation techniques to support the validation of computational fluid dynamics analyses of medical devices. This work is an extension of a previous FDA-sponsored multi-laboratory study, which used a medical device mimicking geometry referred to as the FDA benchmark nozzle model. Experimental measurements were performed using time-resolved PIV at five overlapping regions of the model for Reynolds numbers in the nozzle throat of 500, 2000, 5000, and 8000. Images included a twofold increase in spatial resolution in comparison to the previous study. Data was processed using ensemble correlation, dynamic range enhancement, and phase correlations to increase signal-to-noise ratios and measurement accuracy, and to resolve flow regions with large velocity ranges and gradients, which is typical of many blood-contacting medical devices. Parameters relevant to device safety, including shear stress at the wall and in bulk flow, were computed using radial basis functions. In addition, in-field spatially resolved pressure distributions, Reynolds stresses, and energy dissipation rates were computed from PIV measurements. Velocity measurement uncertainty was estimated directly from the PIV correlation plane, and uncertainty analysis for wall shear stress at each measurement location was performed using a Monte Carlo model. Local velocity uncertainty varied greatly and depended largely on local conditions such as particle seeding, velocity gradients, and particle displacements. Uncertainty in low velocity regions in the sudden expansion section of the nozzle was greatly reduced by over an order of magnitude when dynamic range enhancement was applied. Wall shear stress uncertainty was dominated by uncertainty contributions from velocity estimations, which were shown to account for 90-99% of the total uncertainty. This study provides advancements in the PIV processing methodologies over the previous work through increased PIV image resolution, use of robust image processing algorithms for near-wall velocity measurements and wall shear stress calculations, and uncertainty analyses for both velocity and wall shear stress measurements. The velocity and shear stress analysis, with spatially distributed uncertainty estimates, highlights the challenges of flow quantification in medical devices and provides potential methods to overcome such challenges.
Rheological characterization of modified foodstuffs with food grade thickening agents

NASA Astrophysics Data System (ADS)

Reyes-Ocampo, I.; Aguayo-Vallejo, JP; Ascanio, G.; Córdova-Aguilar, MS

2017-01-01

This work describes a rheological characterization in terms of shear and extensional properties of whole milk, modified with food grade thickening agents (xanthan and carboxymethyl cellulose) with the purpose of being utilized in dysphagia treatment. Shear viscosity of the thickened fluids (2% wt. of xanthan and CMC) were measured in a stress-controlled rheometer and for extensional viscosity, a custom-built orifice flowmeter was used, with elongation rates from 20 to 3000 s-1. Such elongation-rate values represent the entire swallowing process, including the pharyngeal and esophageal phases. The steady-state shear and extensional flow curves were compared with the flow curve of a pudding consistency BaSO4 suspension (α=05), typically used as a reference fluid for the specialized commercial dysphagia products. The modified fluids presented non-Newtonian behavior in both, shear and extensional flows, and the comparison with the reference fluid show that the thickened milk prepared here, can be safely used for consumption by patients with severe dysphagia.
Dynamic stress changes during earthquake rupture

USGS Publications Warehouse

Day, S.M.; Yu, G.; Wald, D.J.

1998-01-01

We assess two competing dynamic interpretations that have been proposed for the short slip durations characteristic of kinematic earthquake models derived by inversion of earthquake waveform and geodetic data. The first interpretation would require a fault constitutive relationship in which rapid dynamic restrengthening of the fault surface occurs after passage of the rupture front, a hypothesized mechanical behavior that has been referred to as "self-healing." The second interpretation would require sufficient spatial heterogeneity of stress drop to permit rapid equilibration of elastic stresses with the residual dynamic friction level, a condition we refer to as "geometrical constraint." These interpretations imply contrasting predictions for the time dependence of the fault-plane shear stresses. We compare these predictions with dynamic shear stress changes for the 1992 Landers (M 7.3), 1994 Northridge (M 6.7), and 1995 Kobe (M 6.9) earthquakes. Stress changes are computed from kinematic slip models of these earthquakes, using a finite-difference method. For each event, static stress drop is highly variable spatially, with high stress-drop patches embedded in a background of low, and largely negative, stress drop. The time histories of stress change show predominantly monotonic stress change after passage of the rupture front, settling to a residual level, without significant evidence for dynamic restrengthening. The stress change at the rupture front is usually gradual rather than abrupt, probably reflecting the limited resolution inherent in the underlying kinematic inversions. On the basis of this analysis, as well as recent similar results obtained independently for the Kobe and Morgan Hill earthquakes, we conclude that, at the present time, the self-healing hypothesis is unnecessary to explain earthquake kinematics.
On the role of constant-stress surfaces in the problem of minimizing elastic stress concentration

NASA Technical Reports Server (NTRS)

Wheeler, L.

1976-01-01

Cases involving antiplane shear deformation, axisymmetric torsion, and plane strain theory, with surfaces of constant stress magnitude optimal in terms of minimizing stress, are investigated. Results for the plane theory refer to exterior doubly connected domains. Stresses generated by torsion of an elastic solid lying within a radially convex region of revolution with plane ends, body force absent, and lateral surface traction-free, are examined. The unknown portion of the boundary of such domains may involve a hole, fillet, or notch.
Earthquake stress drops, ambient tectonic stresses and stresses that drive plate motions

USGS Publications Warehouse

Hanks, T.C.

1977-01-01

A variety of geophysical observations suggests that the upper portion of the lithosphere, herein referred to as the elastic plate, has long-term material properties and frictional strength significantly greater than the lower lithosphere. If the average frictional stress along the non-ridge margin of the elastic plate is of the order of a kilobar, as suggested by the many observations of the frictional strength of rocks at mid-crustal conditions of pressure and temperature, the only viable mechanism for driving the motion of the elastic plate is a basal shear stress of several tens of bars. Kilobars of tectonic stress are then an ambient, steady condition of the earth's crust and uppermost mantle. The approximate equality of the basal shear stress and the average crustal earthquake stress drop, the localization of strain release for major plate margin earthquakes, and the rough equivalence of plate margin slip rates and gross plate motion rates suggest that the stress drops of major plate margin earthquakes are controlled by the elastic release of the basal shear stress in the vicinity of the plate margin, despite the existence of kilobars of tectonic stress existing across vertical planes parallel to the plate margin. If the stress differences available to be released at the time of faulting are distributed in a random, white fasbion with a mean-square value determined by the average earthquake stress drop, the frequency of occurrence of constant stress drop earthquakes will be proportional to reciprocal faulting area, in accordance with empirically known frequency of occurrence statistics. ?? 1977 Birkha??user Verlag.
Time-dependent rheological behavior of natural polysaccharide xanthan gum solutions in interrupted shear and step-incremental/reductional shear flow fields

NASA Astrophysics Data System (ADS)

Lee, Ji-Seok; Song, Ki-Won

2015-11-01

The objective of the present study is to systematically elucidate the time-dependent rheological behavior of concentrated xanthan gum systems in complicated step-shear flow fields. Using a strain-controlled rheometer (ARES), step-shear flow behaviors of a concentrated xanthan gum model solution have been experimentally investigated in interrupted shear flow fields with a various combination of different shear rates, shearing times and rest times, and step-incremental and step-reductional shear flow fields with various shearing times. The main findings obtained from this study are summarized as follows. (i) In interrupted shear flow fields, the shear stress is sharply increased until reaching the maximum stress at an initial stage of shearing times, and then a stress decay towards a steady state is observed as the shearing time is increased in both start-up shear flow fields. The shear stress is suddenly decreased immediately after the imposed shear rate is stopped, and then slowly decayed during the period of a rest time. (ii) As an increase in rest time, the difference in the maximum stress values between the two start-up shear flow fields is decreased whereas the shearing time exerts a slight influence on this behavior. (iii) In step-incremental shear flow fields, after passing through the maximum stress, structural destruction causes a stress decay behavior towards a steady state as an increase in shearing time in each step shear flow region. The time needed to reach the maximum stress value is shortened as an increase in step-increased shear rate. (iv) In step-reductional shear flow fields, after passing through the minimum stress, structural recovery induces a stress growth behavior towards an equilibrium state as an increase in shearing time in each step shear flow region. The time needed to reach the minimum stress value is lengthened as a decrease in step-decreased shear rate.
Progressive softening of brittle-ductile transition due to interplay between chemical and deformation processes

NASA Astrophysics Data System (ADS)

Jeřábek, Petr; Bukovská, Zita; Morales, Luiz F. G.

2017-04-01

The micro-scale shear zones (shear bands) in granitoids from the South Armorican Shear Zone reflect localization of deformation and progressive weakening in the conditions of brittle-ductile transition. We studied microstructures in the shear bands with the aim to establish their P-T conditions and to derive stress and strain rates for specific deformation mechanisms. The evolving microstructure within shear bands documents switches in deformation mechanisms related to positive feedbacks between deformation and chemical processes and imposes mechanical constraints on the evolution of the brittle-ductile transition in the continental transform fault domains. The metamorphic mineral assemblage present in the shear bands indicate their formation at 300-350 ˚ C and 100-400 MPa. Focusing on the early development of shear bands, we identified three stages of shear band evolution. The early stage I associated with initiation of shear bands occurs via formation of microcracks with possible yielding differential stress of up to 250 MPa (Diamond and Tarantola, 2015). Stage II is associated with subgrain rotation recrystallization and dislocation creep in quartz and coeval dissolution-precipitation creep of microcline. Recrystallized quartz grains in shear bands show continual increase in size, and decrease in stress and strain rates from 94 MPa to 17-26 MPa (Stipp and Tullis, 2003) and 3.8*10-12 s-1- 1.8*10-14 s-1 (Patterson and Luan, 1990) associated with deformation partitioning into weaker microcline layer and shear band widening. The quartz mechanical data allowed us to set some constrains for coeval dissolution-precipitation of microcline which at our estimated P-T conditions suggests creep at 17-26 MPa differential stress and 3.8*10-13 s-1 strain rate. Stage III is characterized by localized slip along interconnected white mica bands accommodated by dislocation creep at strain rate 3.8*10-12 s-1 and stress 9.36 MPa (Mares and Kronenberg, 1993). The studied example documents a competition between shear zone widening and narrowing mechanisms, i.e. distributed and localized deformation, depending on the specific mineral phase and deformation mechanism active in each moment of the shear zone evolution. In addition, our mechanical data point to dynamic evolution of the studied brittle-ductile transition characterized by major weakening to strengths ˜10 MPa. Such non-steady-state evolution may be common in crustal shear zones especially when phase transformations are involved. References: Diamond, L. W., and A. Tarantola (2015), Interpretation of fluid inclusions in quartz deformed by weak ductile shearing: Reconstruction of differential stress magnitudes and pre-deformation fluid properties, Earth Planet. Sci. Lett., 417, 107-119. Mares, V. M., and A. K. Kronenberg (1993), Experimental deformation of muscovite, J. Struct. Geol., 15(9), 1061-1075. Paterson, M. S., and F. C. Luan (1990), Quartzite rheology under geological conditions, Geol. Soc. London, Spec. Publ., 54(1), 299-307. Stipp, M., and J. Tullis (2003), The recrystallized grain size piezometer for quartz, Geophys. Res. Lett., 30(21), 1-5.
Wall shear stress characterization of a 3D bluff-body separated flow

NASA Astrophysics Data System (ADS)

Fourrié, Grégoire; Keirsbulck, Laurent; Labraga, Larbi

2013-10-01

Efficient flow control strategies aimed at reducing the aerodynamic drag of road vehicles require a detailed knowledge of the reference flow. In this work, the flow around the rear slanted window of a generic car model was experimentally studied through wall shear stress measurements using an electrochemical method. The mean and fluctuating wall shear stress within the wall impact regions of the recirculation bubble and the main longitudinal vortex structures which develop above the rear window are presented. Correlations allow a more detailed characterization of the recirculation phenomenon within the separation bubble. In the model symmetry plane the recirculation structure compares well with simpler 2D configurations; specific lengths, flapping motion and shedding of large-scale vortices are observed, these similarities diminish when leaving the middle plane due to the strong three-dimensionality of the flow. A specific attention is paid to the convection processes occurring within the recirculation: a downstream convection velocity is observed, in accordance with 2D recirculations from the literature, and an upstream convection is highlighted along the entire bubble length which has not been underlined in some previous canonical configurations.
Experimental study on the bed shear stress under breaking waves

NASA Astrophysics Data System (ADS)

Hao, Si-yu; Xia, Yun-feng; Xu, Hua

2017-06-01

The object of present study is to investigate the bed shear stress on a slope under regular breaking waves by a novel instrument named Micro-Electro-Mechanical System (MEMS) flexible hot-film shear stress sensor. The sensors were calibrated before application, and then a wave flume experiment was conducted to study the bed shear stress for the case of regular waves spilling and plunging on a 1:15 smooth PVC slope. The experiment shows that the sensor is feasible for the measurement of the bed shear stress under breaking waves. For regular incident waves, the bed shear stress is mainly periodic in both outside and inside the breaking point. The fluctuations of the bed shear stress increase significantly after waves breaking due to the turbulence and vortexes generated by breaking waves. For plunging breaker, the extreme value of the mean maximum bed shear stress appears after the plunging point, and the more violent the wave breaks, the more dramatic increase of the maximum bed shear stress will occur. For spilling breaker, the increase of the maximum bed shear stress along the slope is gradual compared with the plunging breaker. At last, an empirical equation about the relationship between the maximum bed shear stress and the surf similarity parameter is given, which can be used to estimate the maximum bed shear stress under breaking waves in practice.

Measurement of the temperature-dependent threshold shear-stress of red blood cell aggregation.

PubMed

Lim, Hyun-Jung; Nam, Jeong-Hun; Lee, Yong-Jin; Shin, Sehyun

2009-09-01

Red blood cell (RBC) aggregation is becoming an important hemorheological parameter, which typically exhibits temperature dependence. Quite recently, a critical shear-stress was proposed as a new dimensional index to represent the aggregative and disaggregative behaviors of RBCs. The present study investigated the effect of the temperature on the critical shear-stress that is required to keep RBC aggregates dispersed. The critical shear-stress was measured at various temperatures (4, 10, 20, 30, and 37 degrees C) through the use of a transient microfluidic aggregometry. The critical shear-stress significantly increased as the blood temperature lowered, which accorded with the increase in the low-shear blood viscosity with the lowering of the temperature. Furthermore, the critical shear-stress also showed good agreement with the threshold shear-stress, as measured in a rotational Couette flow. These findings assist in rheologically validating the critical shear-stress, as defined in the microfluidic aggregometry.
ESTIMATION OF EFFECTIVE SHEAR STRESS WORKING ON FLAT SHEET MEMBRANE USING FLUIDIZED MEDIA IN MBRs

NASA Astrophysics Data System (ADS)

Zaw, Hlwan Moe; Li, Tairi; Nagaoka, Hiroshi; Mishima, Iori

This study was aimed at estimating effective shear stress working on flat sheet membrane by the addition of fluidized media in MBRs. In both of laboratory-scale aeration tanks with and without fluidized media, shear stress variations on membrane surface and water phase velocity variations were measured and MBR operation was conducted. For the evaluation of the effective shear stress working on membrane surface to mitigate membrane surface, simulation of trans-membrane pressure increase was conducted. It was shown that the time-averaged absolute value of shear stress was smaller in the reactor with fluidized media than without fluidized media. However, due to strong turbulence in the reactor with fluidized media caused by interaction between water-phase and media and also due to the direct interaction between membrane surface and fluidized media, standard deviation of shear stress on membrane surface was larger in the reactor with fluidized media than without media. Histograms of shear stress variation data were fitted well to normal distribution curves and mean plus three times of standard deviation was defined to be a maximum shear stress value. By applying the defined maximum shear stress to a membrane fouling model, trans-membrane pressure curve in the MBR experiment was simulated well by the fouling model indicting that the maximum shear stress, not time-averaged shear stress, can be regarded as an effective shear stress to prevent membrane fouling in submerged flat-sheet MBRs.
Meshless analysis of shear deformable shells: the linear model

NASA Astrophysics Data System (ADS)

Costa, Jorge C.; Tiago, Carlos M.; Pimenta, Paulo M.

2013-10-01

This work develops a kinematically linear shell model departing from a consistent nonlinear theory. The initial geometry is mapped from a flat reference configuration by a stress-free finite deformation, after which, the actual shell motion takes place. The model maintains the features of a complete stress-resultant theory with Reissner-Mindlin kinematics based on an inextensible director. A hybrid displacement variational formulation is presented, where the domain displacements and kinematic boundary reactions are independently approximated. The resort to a flat reference configuration allows the discretization using 2-D Multiple Fixed Least-Squares (MFLS) on the domain. The consistent definition of stress resultants and consequent plane stress assumption led to a neat formulation for the analysis of shells. The consistent linear approximation, combined with MFLS, made possible efficient computations with a desired continuity degree, leading to smooth results for the displacement, strain and stress fields, as shown by several numerical examples.
S-shaped flow curves of shear thickening suspensions: direct observation of frictional rheology.

PubMed

Pan, Zhongcheng; de Cagny, Henri; Weber, Bart; Bonn, Daniel

2015-09-01

We study the rheological behavior of concentrated granular suspensions of simple spherical particles. Under controlled stress, the system exhibits an S-shaped flow curve (stress vs shear rate) with a negative slope in between the low-viscosity Newtonian regime and the shear thickened regime. Under controlled shear rate, a discontinuous transition between the two states is observed. Stress visualization experiments with a fluorescent probe suggest that friction is at the origin of shear thickening. Stress visualization shows that the stress in the system remains homogeneous (no shear banding) if a stress is imposed that is intermediate between the high- and low-stress branches. The S-shaped shear thickening is then due to the discontinuous formation of a frictional force network between particles upon increasing the stress.
Experimental Research on Boundary Shear Stress in Typical Meandering Channel

NASA Astrophysics Data System (ADS)

Chen, Kai-hua; Xia, Yun-feng; Zhang, Shi-zhao; Wen, Yun-cheng; Xu, Hua

2018-06-01

A novel instrument named Micro-Electro-Mechanical System (MEMS) flexible hot-film shear stress sensor was used to study the boundary shear stress distribution in the generalized natural meandering open channel, and the mean sidewall shear stress distribution along the meandering channel, and the lateral boundary shear stress distribution in the typical cross-section of the meandering channel was analysed. Based on the measurement of the boundary shear stress, a semi-empirical semi-theoretical computing approach of the boundary shear stress was derived including the effects of the secondary flow, sidewall roughness factor, eddy viscosity and the additional Reynolds stress, and more importantly, for the first time, it combined the effects of the cross-section central angle and the Reynolds number into the expressions. Afterwards, a comparison between the previous research and this study was developed. Following the result, we found that the semi-empirical semi-theoretical boundary shear stress distribution algorithm can predict the boundary shear stress distribution precisely. Finally, a single factor analysis was conducted on the relationship between the average sidewall shear stress on the convex and concave bank and the flow rate, water depth, slope ratio, or the cross-section central angle of the open channel bend. The functional relationship with each of the above factors was established, and then the distance from the location of the extreme sidewall shear stress to the bottom of the open channel was deduced based on the statistical theory.
A higher-order theory for geometrically nonlinear analysis of composite laminates

NASA Technical Reports Server (NTRS)

Reddy, J. N.; Liu, C. F.

1987-01-01

A third-order shear deformation theory of laminated composite plates and shells is developed, the Navier solutions are derived, and its finite element models are developed. The theory allows parabolic description of the transverse shear stresses, and therefore the shear correction factors of the usual shear deformation theory are not required in the present theory. The theory also accounts for the von Karman nonlinear strains. Closed-form solutions of the theory for rectangular cross-ply and angle-ply plates and cross-ply shells are developed. The finite element model is based on independent approximations of the displacements and bending moments (i.e., mixed finite element model), and therefore, only C sup o -approximation is required. The finite element model is used to analyze cross-ply and angle-ply laminated plates and shells for bending and natural vibration. Many of the numerical results presented here should serve as references for future investigations. Three major conclusions resulted from the research: First, for thick laminates, shear deformation theories predict deflections, stresses and vibration frequencies significantly different from those predicted by classical theories. Second, even for thin laminates, shear deformation effects are significant in dynamic and geometrically nonlinear analyses. Third, the present third-order theory is more accurate compared to the classical and firt-order theories in predicting static and dynamic response of laminated plates and shells made of high-modulus composite materials.
A multi-component parallel-plate flow chamber system for studying the effect of exercise-induced wall shear stress on endothelial cells.

PubMed

Wang, Yan-Xia; Xiang, Cheng; Liu, Bo; Zhu, Yong; Luan, Yong; Liu, Shu-Tian; Qin, Kai-Rong

2016-12-28

In vivo studies have demonstrated that reasonable exercise training can improve endothelial function. To confirm the key role of wall shear stress induced by exercise on endothelial cells, and to understand how wall shear stress affects the structure and the function of endothelial cells, it is crucial to design and fabricate an in vitro multi-component parallel-plate flow chamber system which can closely replicate exercise-induced wall shear stress waveforms in artery. The in vivo wall shear stress waveforms from the common carotid artery of a healthy volunteer in resting and immediately after 30 min acute aerobic cycling exercise were first calculated by measuring the inner diameter and the center-line blood flow velocity with a color Doppler ultrasound. According to the above in vivo wall shear stress waveforms, we designed and fabricated a parallel-plate flow chamber system with appropriate components based on a lumped parameter hemodynamics model. To validate the feasibility of this system, human umbilical vein endothelial cells (HUVECs) line were cultured within the parallel-plate flow chamber under abovementioned two types of wall shear stress waveforms and the intracellular actin microfilaments and nitric oxide (NO) production level were evaluated using fluorescence microscope. Our results show that the trends of resting and exercise-induced wall shear stress waveforms, especially the maximal, minimal and mean wall shear stress as well as oscillatory shear index, generated by the parallel-plate flow chamber system are similar to those acquired from the common carotid artery. In addition, the cellular experiments demonstrate that the actin microfilaments and the production of NO within cells exposed to the two different wall shear stress waveforms exhibit different dynamic behaviors; there are larger numbers of actin microfilaments and higher level NO in cells exposed in exercise-induced wall shear stress condition than resting wall shear stress condition. The parallel-plate flow chamber system can well reproduce wall shear stress waveforms acquired from the common carotid artery in resting and immediately after exercise states. Furthermore, it can be used for studying the endothelial cells responses under resting and exercise-induced wall shear stress environments in vitro.
Surface temperatures and glassy state investigations in tribology, part 2

NASA Technical Reports Server (NTRS)

Bair, S. S.; Winer, W. O.

1979-01-01

Measurements of lubricant shear rheological behavior in the amorphous solid region and near the liquid solid transition are reported. Elastic, plastic and viscous behavior was observed. The maximum yield shear stress (limiting shear stress) is a function of temperature and pressure and is believed to be the property which determines the maximum traction in elastohydrodynamic contacts such as traction drives. A shear rheological model based on primary laboratory data is proposed for concentrated contact lubrication. The model is Maxwell model modified with a limiting shear stress. Three material properties are required: low shear stress viscosity, limiting elastic shear modulus, and the limiting shear stress the material can withstand. All three are functions of temperature and pressure.
Shear stress induced stimulation of mammalian cell metabolism

NASA Technical Reports Server (NTRS)

Mcintire, L. V.; Frangos, J. A.; Eskin, S. G.

1988-01-01

A flow apparatus was developed for the study of the metabolic response of anchorage dependent cells to a wide range of steady and pulsatile shear stresses under well controlled conditions. Human umbilical vein endothelial cell monolayers were subjected to steady shear stresses of up to 24 dynes/sq cm, and the production of prostacyclin was determined. The onset of flow led to a burst in prostacyclin production which decayed to a long term steady state rate (SSR). The SSR of cells exposed to flow was greater than the basal release level, and increased linearly with increasing shear stress. It is demonstrated that shear stresses in certain ranges may not be detrimental to mammalian cell metabolism. In fact, throughout the range of shear stresses studied, metabolite production is maximized by maximizing shear stress.
Shear strength of wet granular materials: Macroscopic cohesion and effective stress : Discrete numerical simulations, confronted to experimental measurements.

PubMed

Badetti, Michel; Fall, Abdoulaye; Chevoir, François; Roux, Jean-Noël

2018-05-28

Rheometric measurements on assemblies of wet polystyrene beads, in steady uniform quasistatic shear flow, for varying liquid content within the small saturation (pendular) range of isolated liquid bridges, are supplemented with a systematic study by discrete numerical simulations. The numerical results agree quantitatively with the experimental ones provided that the intergranular friction coefficient is set to the value [Formula: see text], identified from the behaviour of the dry material. Shear resistance and solid fraction [Formula: see text] are recorded as functions of the reduced pressure [Formula: see text], which, defined as [Formula: see text], compares stress [Formula: see text], applied in the velocity gradient direction, to the tensile strength [Formula: see text] of the capillary bridges between grains of diameter a, and characterizes cohesion effects. The simplest Mohr-Coulomb relation with [Formula: see text]-independent cohesion c applies as a good approximation for large enough [Formula: see text] (typically [Formula: see text]. Numerical simulations extend to different values of μ and, compared to experiments, to a wider range of [Formula: see text]. The assumption that capillary stresses act similarly to externally applied ones onto the dry granular contact network (effective stresses) leads to very good (although not exact) predictions of the shear strength, throughout the numerically investigated range [Formula: see text] and [Formula: see text]. Thus, the internal friction coefficient [Formula: see text] of the dry material still relates the contact force contribution to stresses, [Formula: see text], while the capillary force contribution to stresses, [Formula: see text], defines a generalized Mohr-Coulomb cohesion c, depending on [Formula: see text] in general. c relates to [Formula: see text] , coordination numbers and capillary force network anisotropy. c increases with liquid content through the pendular regime interval, to a larger extent, the smaller the friction coefficient. The simple approximation ignoring capillary shear stress [Formula: see text] (referred to as the Rumpf formula) leads to correct approximations for the larger saturation range within the pendular regime, but fails to capture the decrease of cohesion for smaller liquid contents.
Implementation of visual data mining for unsteady blood flow field in an aortic aneurysm.

PubMed

Morizawa, Seiichiro; Shimoyama, Koji; Obayashi, Shigeru; Funamoto, Kenichi; Hayase, Toshiyuki

2011-12-01

This study was performed to determine the relations between the features of wall shear stress and aneurysm rupture. For this purpose, visual data mining was performed in unsteady blood flow simulation data for an aortic aneurysm. The time-series data of wall shear stress given at each grid point were converted to spatial and temporal indices, and the grid points were sorted using a self-organizing map based on the similarity of these indices. Next, the results of cluster analysis were mapped onto the real space of the aortic aneurysm to specify the regions that may lead to aneurysm rupture. With reference to previous reports regarding aneurysm rupture, the visual data mining suggested specific hemodynamic features that cause aneurysm rupture. GRAPHICAL ABSTRACT:
Estimates of Shear Stress and Measurements of Water Levels in the Lower Fox River near Green Bay, Wisconsin

USGS Publications Warehouse

Westenbroek, Stephen M.

2006-01-01

Turbulent shear stress in the boundary layer of a natural river system largely controls the deposition and resuspension of sediment, as well as the longevity and effectiveness of granular-material caps used to cover and isolate contaminated sediments. This report documents measurements and calculations made in order to estimate shear stress and shear velocity on the Lower Fox River, Wisconsin. Velocity profiles were generated using an acoustic Doppler current profiler (ADCP) mounted on a moored vessel. This method of data collection yielded 158 velocity profiles on the Lower Fox River between June 2003 and November 2004. Of these profiles, 109 were classified as valid and were used to estimate the bottom shear stress and velocity using log-profile and turbulent kinetic energy methods. Estimated shear stress ranged from 0.09 to 10.8 dynes per centimeter squared. Estimated coefficients of friction ranged from 0.001 to 0.025. This report describes both the field and data-analysis methods used to estimate shear-stress parameters for the Lower Fox River. Summaries of the estimated values for bottom shear stress, shear velocity, and coefficient of friction are presented. Confidence intervals about the shear-stress estimates are provided.
Mapping the Dynamics of Shear Stress—Induced Structural Changes in Endothelial Cells

PubMed Central

Mott, Rosalind E.; Helmke, Brian P.

2009-01-01

Hemodynamic shear stress regulates endothelial cell biochemical processes that govern cytoskeletal contractility, focal adhesion dynamics, and extracellular matrix assembly. Since shear stress causes rapid strain focusing at discrete locations in the cytoskeleton, we hypothesized that shear stress coordinately alters structural dynamics in the cytoskeleton, focal adhesion sites, and extracellular matrix on a time scale of minutes. Using multi-wavelength 4-D fluorescence microscopy, we measured the displacement of rhodamine-fibronectin and of GFP-labeled actin, vimentin, paxillin, and/or vinculin in aortic endothelial cells before and after onset of steady unidirectional shear stress. In the cytoskeleton, the onset of shear stress increased actin polymerization into lamellipodia, altered the angle of lateral displacement of actin stress fibers and vimentin filaments, and decreased centripetal remodeling of actin stress fibers in both subconfluent and confluent cell layers. Shear stress induced the formation of new focal complexes and reduced the centripetal remodeling of focal adhesions in regions of new actin polymerization. The structural dynamics of focal adhesions and the fibronectin matrix varied with cell density. In subconfluent cell layers, shear stress onset decreased the displacement of focal adhesions and fibronectin fibrils. In confluent monolayers, the direction of fibronectin and focal adhesion displacement shifted significantly towards the downstream direction within one minute after onset of shear stress. These spatially coordinated rapid changes in the structural dynamics of cytoskeleton, focal adhesions, and extracellular matrix are consistent with focusing of mechanical stress and/or strain near major sites of shear stress-mediated mechanotransduction. PMID:17855768
Shear stress reduces protease activated receptor-1 expression in human endothelial cells

NASA Technical Reports Server (NTRS)

Nguyen, K. T.; Eskin, S. G.; Patterson, C.; Runge, M. S.; McIntire, L. V.

2001-01-01

Shear stress has been shown to regulate several genes involved in the thrombotic and proliferative functions of endothelial cells. Thrombin receptor (protease-activated receptor-1: PAR-1) increases at sites of vascular injury, which suggests an important role for PAR-1 in vascular diseases. However, the effect of shear stress on PAR-1 expression has not been previously studied. This work investigates effects of shear stress on PAR-1 gene expression in both human umbilical vein endothelial cells (HUVECs) and microvascular endothelial cells (HMECs). Cells were exposed to different shear stresses using a parallel plate flow system. Northern blot and flow cytometry analysis showed that shear stress down-regulated PAR-1 messenger RNA (mRNA) and protein levels in both HUVECs and HMECs but with different thresholds. Furthermore, shear-reduced PAR-1 mRNA was due to a decrease of transcription rate, not increased mRNA degradation. Postshear stress release of endothelin-1 in response to thrombin was reduced in HUVECs and HMECs. Moreover, inhibitors of potential signaling pathways applied during shear stress indicated mediation of the shear-decreased PAR-1 expression by protein kinases. In conclusion, shear stress exposure reduces PAR-1 gene expression in HMECs and HUVECs through a mechanism dependent in part on protein kinases, leading to altered endothelial cell functional responses to thrombin.
Intermittent hydrostatic pressure inhibits shear stress-induced nitric oxide release in human osteoarthritic chondrocytes in vitro.

PubMed

Lee, Mel S; Trindade, Michael C D; Ikenoue, Takashi; Schurman, David J; Goodman, Stuart B; Smith, R Lane

2003-02-01

To test the effects of intermittent hydrostatic pressure (IHP) on nitric oxide (NO) release induced by shear stress and matrix macromolecule gene expression in human osteoarthritic chondrocytes in vitro. Chondrocytes isolated from cartilage samples from 9 patients with osteoarthritis were cultured and exposed to either shear stress or an NO donor. Nitrite concentration was measured using the Griess reaction. Matrix macromolecule mRNA signal levels were determined using reverse-transcriptase polymerase chain reaction and quantified by imaging analysis software. Exposure to shear stress upregulated NO release in a dose and time-dependent manner. Application of IHP inhibited shear stress induced NO release but did not alter NO release from chondrocytes not exposed to shear stress. Shear stress induced NO or addition of an NO donor (sodium nitroprusside) was associated with decreased mRNA signal levels for the cartilage matrix proteins, aggrecan, and type II collagen. Intermittent hydrostatic pressure blocked the inhibitory effects of sodium nitroprusside but did not alter the inhibitory effects of shear stress on cartilage macromolecule gene expression. Our data show that shear stress and IHP differentially alter chondrocyte metabolism and suggest that a balance of effects between different loading forces preserve cartilage extracellular matrix in vivo.
Effects of shear stress on the microalgae Chaetoceros muelleri

PubMed Central

van der Goot, Atze J.; Norsker, Niels-Henrik; Wijffels, René H.

2010-01-01

The effect of shear stress on the viability of Chaetoceros muelleri was studied using a combination of a rheometer and dedicated shearing devices. Different levels of shear stress were applied by varying the shear rates and the medium viscosities. It was possible to quantify the effect of shear stress over a wide range, whilst preserving laminar flow conditions through the use of a thickening agent. The threshold value at which the viability of algae was negatively influenced was between 1 and 1.3 Pa. Beyond the threshold value the viability decreased suddenly to values between 52 and 66%. The effect of shear stress was almost time independent compared to normal microalgae cultivation times. The main shear stress effect was obtained within 1 min, with a secondary effect of up to 8 min. PMID:20191365
Model Estimates of Non-Hydrostatic Stresses in the Martian Crust and Mantle: 1—Two-Level Model

NASA Astrophysics Data System (ADS)

Gudkova, T. V.; Batov, A. V.; Zharkov, V. N.

2017-11-01

Regions of maximum shear and tension-compression stresses in the Martian interior have been revealed using two types of models: the elastic model and the model with an elastic lithosphere of varied thickness (150-500 km) positioned on a weak layer that has partially lost its elastic properties. The weakening is simulated by a ten-fold lower value of the shear modulus down to the core boundary. The numerical simulation applies Green's functions (load number method) with the step of 1 × 1 grade along latitude and longitude down to a depth of 1000 km. The boundary condition is the expansion of the latest data on Martian topography and the gravitational field (model MRO120D) in spherical harmonics up to the degree and order of 90 in relation to the reference surface that is assumed an equilibrium spheroid. The considered two-level compensation model assumes nonequilibrium relief and density anomalies at the crust-mantle boundary to be the sources of the anomalous gravitational field. Calculations are performed for two test models of Martian internal structure with the crust mean thicknesses of 50 to 100 km and mean density of 2900 kg/m3. Considerable tangential and simultaneously compressive stresses occur under the Tharsis region. The main regions of high shear and simultaneously extentional stresses are located in the Hellas region crust and in the lithosphere of the following regions: Argyre Planitia, Mare Acidalium, Arcadia Planitia and Valles Marineris. The zone of high maximum shear and extentional stresses has been found at the base of the lithosphere under the Olympus volcano and that under the Elysium rise.
A dynamic jamming point for shear thickening suspensions

NASA Astrophysics Data System (ADS)

Brown, Eric; Jaeger, Heinrich

2008-11-01

Densely packed suspensions can shear thicken, in which the viscosity increases with shear rate. We performed rheometry measurements on two model systems: corn starch in water and glass spheres in oils. In both systems we observed shear thickening up to a critical packing fraction φc (=0.55 for spherical grains) above which the flow abruptly transitions to shear thinning. The viscosity and yield stress diverge as power laws at φc. Extrapolating the dynamic ranges of shear rate and stress in the shear thickening regime up to φc suggests a finite change in shear stress with zero change in shear rate. This is a dynamic analog to the jamming point with a yield stress at zero shear rate.
Process viscometry in flows of non-Newtonian fluids using an anchor agitator

NASA Astrophysics Data System (ADS)

Jo, Hae Jin; Jang, Hye Kyeong; Kim, Young Ju; Hwang, Wook Ryol

2017-11-01

In this work, we present a viscosity measurement technique for inelastic non-Newtonian fluids directly in flows of anchor agitators that are commonly used in highly viscous fluid mixing particularly with yield stress. A two-blade anchor impeller is chosen as a model flow system and Carbopol 940 solutions and Xanthan gum solutions with various concentrations are investigated as test materials. Following the Metzner-Otto correlation, the effective shear rate constant and the energy dissipation rate constant have been estimated experimentally by establishing (i) the relationship between the power number and the Reynolds number using a reference Newtonian fluid and (ii) the proportionality between the effective shear rate and the impeller speed with a reference non-Newtonian fluid. The effective viscosity that reproduces the same amount of the energy dissipation rate, corresponding to that of Newtonian fluid, has been obtained by measuring torques for various impeller speeds and the accuracy in the viscosity prediction as a function of the shear rate has been compared with the rheological measurement. We report that the process viscometry with the anchor impeller yields viscosity estimation within the relative error of 20% with highly shear-thinning fluids.
Flume Experiments on the Influence of Salmon Spawning Density on Grain Stability and Bedload Transport in Gravel-bed Streams

NASA Astrophysics Data System (ADS)

Buxton, T. H.

2015-12-01

Salmon spawning in streams involves the female salmon digging a pit in the bed where she deposits eggs for fertilization before covering them with gravel excavated from the next pit upstream. Sequences of pit excavation and filling winnow fines, loosen sediment, and move bed material into a tailspill mound resembling the shape of a dune. Research suggests salmonid nests (redds) destabilize streambeds by reducing friction between loosened grains and converging flow that elevates shear stress on redd topography. However, bed stability may be enhanced by form drag from redds in clusters that lower shear stress on the granular bed, but this effect will vary with the proportion of the bed surface that is occupied by redds (P). I used simulated redds and water-worked ("unspawned") beds in a laboratory flume to evaluate these competing influences on grain stability and bedload transport rates with P=0.12, 0.34, and 0.41. Results indicate that competence (largest-grain) and reference transport rate estimates of critical conditions for particle entrainment inversely relate to P. Bedload transport increased as exponential functions of P and excess boundary shear stress. Therefore, redd form drag did not overcome the destabilizing effects of spawning. Instead, grain mobility and bedload transport increased with P because larger areas of the bed were composed of relatively loose, unstable grains and redd topography that experienced elevated shear stress. Consequently, the presence of redds in fish-bearing streams likely reduces the effects of sedimentation from landscape disturbance on stream habitats that salmon use for reproduction.

On double shearing in frictional materials

NASA Astrophysics Data System (ADS)

Teunissen, J. A. M.

2007-01-01

This paper evaluates the mechanical behaviour of yielding frictional geomaterials. The general Double Shearing model describes this behaviour. Non-coaxiality of stress and plastic strain increments for plane strain conditions forms an important part of this model. The model is based on a micro-mechanical and macro-mechanical formulation. The stress-dilatancy theory in the model combines the mechanical behaviour on both scales.It is shown that the general Double Shearing formulation comprises other Double Shearing models. These models differ in the relation between the mobilized friction and dilatancy and in non-coaxiality. In order to describe reversible and irreversible deformations the general Double Shearing model is extended with elasticity.The failure of soil masses is controlled by shear mechanisms. These shear mechanisms are determined by the conditions along the shear band. The shear stress ratio of a shear band depends on the orientation of the stress in the shear band. There is a difference between the peak strength and the residual strength in the shear band. While peak stress depends on strength properties only, the residual strength depends upon the yield conditions and the plastic deformation mechanisms and is generally considerably lower than the maximum strength. It is shown that non-coaxial models give non-unique solutions for the shear stress ratio on the shear band. The Double Shearing model is applied to various failure problems of soils such as the direct simple shear test, the biaxial test, infinite slopes, interfaces and for the calculation of the undrained shear strength. Copyright
Room temperature shear properties of the strain isolator pad for the shuttle thermal protection system

NASA Technical Reports Server (NTRS)

Sawyer, J. W.; Waters, W. A., Jr.

1981-01-01

Tests were conducted at room temperature to determine the shear properties of the strain isolator pad (SIP) material used in the thermal protection system of the space shuttle. Tests were conducted on both the .23 cm and .41 cm thick SIP material in the virgin state and after fifty fully reversed shear cycles. The shear stress displacement relationships are highly nonlinear, exhibit large hysteresis effects, are dependent on material orientation, and have a large low modulus region near the zero stress level where small changes in stress can result in large displacements. The values at the higher stress levels generally increase with normal and shear force load conditioning. Normal forces applied during the shear tests reduces the low modulus region for the material. Shear test techniques which restrict the normal movement of the material give erroneous stress displacement results. However, small normal forces do not significantly effect the shear modulus for a given shear stress. Poisson's ratio values for the material are within the range of values for many common materials. The values are not constant but vary as a function of the stress level and the previous stress history of the material. Ultimate shear strengths of the .23 cm thick SIP are significantly higher than those obtained for the .41 cm thick SIP.
Circulatory shear flow alters the viability and proliferation of circulating colon cancer cells

NASA Astrophysics Data System (ADS)

Fan, Rong; Emery, Travis; Zhang, Yongguo; Xia, Yuxuan; Sun, Jun; Wan, Jiandi

2016-06-01

During cancer metastasis, circulating tumor cells constantly experience hemodynamic shear stress in the circulation. Cellular responses to shear stress including cell viability and proliferation thus play critical roles in cancer metastasis. Here, we developed a microfluidic approach to establish a circulatory microenvironment and studied circulating human colon cancer HCT116 cells in response to a variety of magnitude of shear stress and circulating time. Our results showed that cell viability decreased with the increase of circulating time, but increased with the magnitude of wall shear stress. Proliferation of cells survived from circulation could be maintained when physiologically relevant wall shear stresses were applied. High wall shear stress (60.5 dyne/cm2), however, led to decreased cell proliferation at long circulating time (1 h). We further showed that the expression levels of β-catenin and c-myc, proliferation regulators, were significantly enhanced by increasing wall shear stress. The presented study provides a new insight to the roles of circulatory shear stress in cellular responses of circulating tumor cells in a physiologically relevant model, and thus will be of interest for the study of cancer cell mechanosensing and cancer metastasis.
Characteristics of Asperity Damage and Its Influence on the Shear Behavior of Granite Joints

NASA Astrophysics Data System (ADS)

Meng, Fanzhen; Zhou, Hui; Wang, Zaiquan; Zhang, Chuanqing; Li, Shaojun; Zhang, Liming; Kong, Liang

2018-02-01

Surface roughness significantly affects the shear behavior of rock joints; thus, studies on the asperity damage characteristics and its influence on the shear behavior of joints are extremely important. In this paper, shear tests were conducted on tensile granite joints; asperity damage was evaluated based on acoustic emission (AE) events; and the influence of asperity damage on joint shear behavior was analyzed. The results indicated that the total AE events tended to increase with normal stress. In addition, the asperity damage initiation shear stress, which is defined as the transition point from slow growth to rapid growth in the cumulative events curve, was approximately 0.485 of the peak shear strength regardless of the normal stress. Moreover, 63-85% of the AE events were generated after the peak shear stress, indicating that most of the damage occurred in this stage. Both the dilation and the total AE events decreased with shear cycles because of the damage inflicted on asperities during the previous shear cycle. Two stages were observed in the normal displacement curves under low normal stress, whereas three stages (compression, dilation and compression again) were observed at a higher normal stress; the second compression stage may be caused by tensile failure outside the shear plane. The magnitude of the normal stress and the state of asperity are two important factors controlling the post-peak stress drop and stick-slip of granite joints. Serious deterioration of asperities will stop stick-slip from recurring under the same normal stress because the ability to accumulate energy is decreased. The AE b-value increases with the number of shear cycles, indicating that the stress concentration inside the fault plane is reduced because of asperity damage; thus, the potential for dynamic disasters, such as fault-slip rockbursts, will be decreased.
High fluid shear strain causes injury in silver shark: Preliminary implications for Mekong hydropower turbine design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baumgartner, L. J.; Thorncraft, G.; Phonekhampheng, O.

Fluid shear arises when two bodies of water, travelling at different velocities, intersect. Fish entrained at the interface of these two water masses will experience shear stress; which can be harmful. The stress magnitude is dependent on waterbody mass and velocity; with the fish impact largely related to body size. Elevated shear stress occurs where rapidly flowing water passes near spillways, across screens, within turbine draft tubes or other passage routes. A flume was used to determine critical tolerances of silver shark (Balantiocheilos melanopterus) to different shear stress rates generated by a high velocity jet. Fish experienced higher levels ofmore » injury and mortality as shear stress was increased. Excessive shear forces had damaging impacts on fish. Mortality occurred at shear levels higher that 600/s. It is important that developers should attempt to model potential shear profiles expected during turbine passage in selected designs. These data will be critical to determine potential impacts on fish. If the likelihood of adverse impact is high, then alternative designs which have lower shear stress could be explored.« less
Direct Shear Tests of Sandstone Under Constant Normal Tensile Stress Condition Using a Simple Auxiliary Device

NASA Astrophysics Data System (ADS)

Cen, Duofeng; Huang, Da

2017-06-01

Tension-shear failure is a typical failure mode in the rock masses in unloading zones induced by excavation or river incision, etc., such as in excavation-disturbed zone of deep underground caverns and superficial rocks of high steep slopes. However, almost all the current shear failure criteria for rock are usually derived on the basis of compression-shear failure. This paper proposes a simple device for use with a servo-controlled compression-shear testing machine to conduct the tension-shear tests of cuboid rock specimens, to test the direct shear behavior of sandstone under different constant normal tensile stress conditions ( σ = -1, -1.5, -2, -2.5 and -3 MPa) as well as the uniaxial tension behavior. Generally, the fracture surface roughness decreases and the proportion of comminution areas in fracture surface increases as the change of stress state from tension to tension-shear and to compression-shear. Stepped fracture is a primary fracture pattern in the tension-shear tests. The shear stiffness, shear deformation and normal deformation (except the normal deformation for σ = -1 MPa) decrease during shearing, while the total normal deformation containing the pre-shearing portion increases as the normal tensile stress level (| σ|) goes up. Shear strength is more sensitive to the normal tensile stress than to the normal compressive stress, and the power function failure criterion (or Mohr envelope form of Hoek-Brown criterion) is examined to be the optimal criterion for the tested sandstone in the full region of tested normal stress in this study.
Critical shear stress measurement of cohesive soils in streams: identifying device-dependent variability using an in-situ jet test device and conduit flume

NASA Astrophysics Data System (ADS)

Mahalder, B.; Schwartz, J. S.; Palomino, A.; Papanicolaou, T.

2016-12-01

Cohesive soil erodibility and threshold shear stress for stream bed and bank are dependent on both soil physical and geochemical properties in association with the channel vegetative conditions. These properties can be spatially variable therefore making critical shear stress measurement in cohesive soil challenging and leads to a need for a more comprehensive understanding of the erosional processes in streams. Several in-situ and flume-type test devices for estimating critical shear stress have been introduced by different researchers; however reported shear stress estimates per device vary widely in orders of magnitude. Advantages and disadvantages exist between these devices. Development of in-situ test devices leave the bed and/or bank material relatively undisturbed and can capture the variable nature of field soil conditions. However, laboratory flumes provide a means to control environmental conditions that can be quantify and tested. This study was conducted to observe differences in critical shear stress using jet tester and a well-controlled conduit flume. Soil samples were collected from the jet test locations and tested in a pressurized flume following standard operational procedure to calculate the critical shear stress. The results were compared using statistical data analysis (mean-separation ANOVA procedure) to identify possible differences. In addition to the device comparison, the mini jet device was used to measure critical shear stress across geologically diverse regions of Tennessee, USA. Statistical correlation between critical shear stress and the soil physical, and geochemical properties were completed identifying that geological origin plays a significant role in critical shear stress prediction for cohesive soils. Finally, the critical shear stress prediction equations using the jet test data were examined with possible suggestions to modify based on the flume test results.
Hemolysis in a laminar flow-through Couette shearing device: an experimental study.

PubMed

Boehning, Fiete; Mejia, Tzahiry; Schmitz-Rode, Thomas; Steinseifer, Ulrich

2014-09-01

Reducing hemolysis has been one of the major goals of rotary blood pump development and in the investigational phase, the capability of hemolysis estimation for areas of elevated shear stresses is valuable. The degree of hemolysis is determined by the amplitude of shear stress and the exposure time, but to date, the exact hemolytic behavior at elevated shear stresses and potential thresholds for subcritical shear exposure remain vague. This study provides experimental hemolysis data for a set of shear stresses and exposure times to allow better estimations of hemolysis for blood exposed to elevated shearing. Heparinized porcine blood with a hematocrit of 40% was mechanically damaged in a flow-through laminar Couette shear flow at a temperature of 23°C. Four levels of shear stress, 24, 592, 702, and 842 Pa, were replicated at two exposure times, 54 and 873 ms. For the calculation of the shear stresses, an apparent viscosity of 5 mPas was used, which was verified in an additional measurement of the blood viscosity. The hemolysis measurements were repeated four times, whereby all conditions were measured once within the same day and with blood from the same source. Samples were taken at the inlet and outlet of the shear region and an increase in plasma-free hemoglobin was measured. An index of hemolysis (IH) was thereby calculated giving the ratio of free to total hemoglobin. The results are compared with data from previously published studies using a similar shearing device. Hemolysis was found to increase exponentially with shear stress, but high standard deviations existed at measurements with elevated IH. At short exposure times, the IH remained low at under 0.5% for all shear stress levels. For high exposure times, the IH increased from 0.84% at 592 Pa up to 3.57% at the highest shear stress level. Hemolysis was significant for shear stresses above ∼600 Pa at the high exposure time of 873 ms. Copyright © 2014 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.
Shear stress-induced calcium transients in endothelial cells from human umbilical cord veins.

PubMed Central

Schwarz, G; Callewaert, G; Droogmans, G; Nilius, B

1992-01-01

1. Changes of the free cytosolic Ca2+ concentration induced by shear stress were measured in Fura-2 acetoxymethyl ester-loaded endothelial cells from human umbilical cord veins. 2. We were able to induce Ca2+ transients in almost every cell by blowing a stream of physiological solution onto a single endothelial cell thereby inducing shear stress between 0 and 50 dyn cm-2. The Ca2+ response could be graded by varying the shear stress, and reached a half-maximal value at a shear stress of 30 dyn cm-2. 3. The shear stress responses critically depended on the extracellular Ca2+ concentration and were absent in a Ca(2+)-free solution. Repetitive application of short pulses of shear stress induced cumulative effects because of the slow decay of the shear stress Ca2+ responses (time constants 82.3 +/- 17.8 s from twenty-five cells). Application of a depolarizing high potassium solution to reduce the driving force for Ca2+ entry decreased the Ca2+ transients in some of the cells. 4. Application of shear stress in the presence of other divalent cations, such as nickel, cobalt or barium, always produced substantial changes in the ratio of the 390/360 nm fluorescence signal, indicating influx of these cations and subsequent quenching of the Fura-2 fluorescence. 5. Shear stress responses in the presence of 10 mM Ca2+ were completely blocked by application of 1 mM La3+. 6. Incubation of the cells with the phorbol ester 12-O-tetradecanoyl phorbol-13-acetate (TPA) did not alter the shear stress response, but completely blocked histamine-induced Ca2+ transients. 7. Small submaximal shear stress potentiated the Ca2+ transients induced by histamine. 8. We conclude that shear stress-dependent Ca2+ signals are induced by an influx of calcium that is not modulated via protein kinase C and not activated by membrane depolarization. The influx pathway is also permeable to divalent cations such as Ni2+, Co2+ and Ba2+, but is blocked by La3+. PMID:1338792
The Fracture Toughness of Nuclear Graphites Grades

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burchell, Timothy D.; Erdman, III, Donald L.; Lowden, Rick R.

2017-04-01

New measurements of graphite mode I critical stress intensity factor, KIc (commonly referred to as the fracture toughness) and the mode II critical shear stress intensity, KIIc, are reported and compared with prior data for KIc and KIIc. The new data are for graphite grades PCEA, IG-110 and 2114. Variations of KIc and acoustic emission (AE) data with graphite texture are reported and discussed. The Codes and Standards applications of fracture toughness, KIc, data are also discussed. A specified minimum value for nuclear graphite KIc is recommended.
A Piezoelectric Shear Stress Sensor

NASA Technical Reports Server (NTRS)

Kim, Taeyang; Saini, Aditya; Kim, Jinwook; Gopalarathnam, Ashok; Zhu, Yong; Palmieri, Frank L.; Wohl, Christopher J.; Jiang, Xiaoning

2016-01-01

In this paper, a piezoelectric sensor with a floating element was developed for shear stress measurement. The piezoelectric sensor was designed to detect the pure shear stress suppressing effects of normal stress generated from the vortex lift-up by applying opposite poling vectors to the: piezoelectric elements. The sensor was first calibrated in the lab by applying shear forces and it showed high sensitivity to shear stress (=91.3 +/- 2.1 pC/Pa) due to the high piezoelectric coefficients of PMN-33%PT (d31=-1330 pC/N). The sensor also showed almost no sensitivity to normal stress (less than 1.2 pC/Pa) because of the electromechanical symmetry of the device. The usable frequency range of the sensor is 0-800 Hz. Keywords: Piezoelectric sensor, shear stress, floating element, electromechanical symmetry
Bed-material entrainment potential, Roaring Fork River at Basalt, Colorado

USGS Publications Warehouse

Elliott, John G.

2002-01-01

The Roaring Fork River at Basalt, Colorado, has a frequently mobile streambed composed of gravel, cobbles, and boulders. Recent urban and highway development on the flood plain, earlier attempts to realign and confine the channel, and flow obstructions such as bridge openings and piers have altered the hydrology, hydraulics, sediment transport, and sediment deposition areas of the Roaring Fork. Entrainment and deposition of coarse sediment on the streambed and in large alluvial bars have reduced the flood-conveying capacity of the river. Previous engineering studies have identified flood-prone areas and hazards related to inundation and high streamflow velocity, but those studies have not evaluated the potential response of the channel to discharges that entrain the coarse streambed. This study builds upon the results of earlier flood studies and identifies some potential areas of concern associated with bed-material entrainment. Cross-section surveys and simulated water-surface elevations from a previously run HEC?RAS model were used to calculate the boundary shear stress on the mean streambed, in the thalweg, and on the tops of adjacent alluvial bars for four reference streamflows. Sediment-size characteristics were determined for surficial material on the streambed, on large alluvial bars, and on a streambank. The median particle size (d50) for the streambed samples was 165 millimeters and for the alluvial bars and bank samples was 107 millimeters. Shear stresses generated by the 10-, 50-, and 100-year floods, and by a more common flow that just inundated most of the alluvial bars in the study reach were calculated at 14 of the cross sections used in the Roaring Fork River HEC?RAS model. The Shields equation was used with a Shields parameter of 0.030 to estimate the critical shear stress for entrainment of the median sediment particle size on the mean streambed, in the thalweg, and on adjacent alluvial bar surfaces at the 14 cross sections. Sediment-entrainment potential for a specific geomorphic surface was expressed as the ratio of the flood-generated boundary shear stress to the critical shear stress (to/tc) with respect to two threshold conditions. The partial entrainment threshold (to/tc=1) is the condition where the mean boundary shear stress (to) equals the critical shear stress for the median particle size (tc) at that cross section. At this threshold discharge, the d50 particle size becomes entrained, but movement of d50-size particles may be limited to a few individual particles or in a small area of the streambed surface. The complete entrainment threshold (to/tc=2) is the condition where to is twice the critical shear stress for the median particle size, the condition where complete or widespread mobilization of the d50 particle-size fraction is anticipated. Entrainment potential for a specific reference streamflow varied greatly in the downstream direction. At some cross sections, the bed or bar material was mobile, whereas at other cross sections, the bed or bar material was immobile for the same discharge. The significance of downstream variability is that sediment entrained at one cross section may be transported into, but not through, a cross section farther downstream, a situation resulting in sediment deposition and possibly progressive aggradation and loss of channel conveyance. Little or no sediment in the d50-size range is likely to be entrained or transported through much of the study reach by the bar-inundating streamflow. However, the entrainment potential at this discharge increases abruptly to more than twice the critical value, then decreases abruptly, at a series of cross sections located downstream from the Emma and Midland Avenue Bridges. Median particle-size sediment is mobile at most cross sections in the study reach during the 10-year flood; however, the bed material is immobile at cross sections just upstream from the Upper Bypass and Midland Avenue Bridges. A similar s
Elastic interactions between two-dimensional geometric defects

NASA Astrophysics Data System (ADS)

Moshe, Michael; Sharon, Eran; Kupferman, Raz

2015-12-01

In this paper, we introduce a methodology applicable to a wide range of localized two-dimensional sources of stress. This methodology is based on a geometric formulation of elasticity. Localized sources of stress are viewed as singular defects—point charges of the curvature associated with a reference metric. The stress field in the presence of defects can be solved using a scalar stress function that generalizes the classical Airy stress function to the case of materials with nontrivial geometry. This approach allows the calculation of interaction energies between various types of defects. We apply our methodology to two physical systems: shear-induced failure of amorphous materials and the mechanical interaction between contracting cells.
Surface temperatures and glassy state investigations in tribology, part 3. [limiting shear stress rheological model

NASA Technical Reports Server (NTRS)

Bair, S.; Winer, W. O.

1980-01-01

Research related to the development of the limiting shear stress rheological model is reported. Techniques were developed for subjecting lubricants to isothermal compression in order to obtain relevant determinations of the limiting shear stress and elastic shear modulus. The isothermal compression limiting shear stress was found to predict very well the maximum traction for a given lubricant. Small amounts of side slip and twist incorporated in the model were shown to have great influence on the rising portion of the traction curve at low slide-roll ratio. The shear rheological model was also applied to a Grubin-like elastohydrodynamic inlet analysis for predicting film thicknesses when employing the limiting shear stress model material behavior.
Contribution of Surface Chemistry to the Shear Thickening of Silica Nanoparticle Suspensions.

PubMed

Yang, Wufang; Wu, Yang; Pei, Xiaowei; Zhou, Feng; Xue, Qunji

2017-01-31

Shear thickening is a general process crucial for many processed products ranging from food and personal care to pharmaceuticals. Theoretical calculations and mathematical simulations of hydrodynamic interactions and granular-like contacts have proved that contact forces between suspended particles dominate the rheological characteristic of colloidal suspensions. However, relevant experimental studies are very rare. This study was conducted to reveal the influence of nanoparticle (NP) interactions on the rheological behavior of shear-thickening fluids (STFs) by changing the colloidal surface chemistries. Silica NPs with various surface chemical compositions are fabricated and used to prepare dense suspensions. Rheological experiments are conducted to determine the influence of NP interactions on corresponding dense suspension systems. The results suggest that the surface chemistries of silica NPs determine the rheological behavior of dense suspensions, including shear-thickening behavior, onset stress, critical volume fraction, and jamming volume fraction. This study provides useful reference for designing effective STFs and regulating their characteristics.
Log-layer mismatch and modeling of the fluctuating wall stress in wall-modeled large-eddy simulations

NASA Astrophysics Data System (ADS)

Yang, Xiang I. A.; Park, George Ilhwan; Moin, Parviz

2017-10-01

Log-layer mismatch refers to a chronic problem found in wall-modeled large-eddy simulation (WMLES) or detached-eddy simulation, where the modeled wall-shear stress deviates from the true one by approximately 15 % . Many efforts have been made to resolve this mismatch. The often-used fixes, which are generally ad hoc, include modifying subgrid-scale stress models, adding a stochastic forcing, and moving the LES-wall-model matching location away from the wall. An analysis motivated by the integral wall-model formalism suggests that log-layer mismatch is resolved by the built-in physics-based temporal filtering. In this work we investigate in detail the effects of local filtering on log-layer mismatch. We show that both local temporal filtering and local wall-parallel filtering resolve log-layer mismatch without moving the LES-wall-model matching location away from the wall. Additionally, we look into the momentum balance in the near-wall region to provide an alternative explanation of how LLM occurs, which does not necessarily rely on the numerical-error argument. While filtering resolves log-layer mismatch, the quality of the wall-shear stress fluctuations predicted by WMLES does not improve with our remedy. The wall-shear stress fluctuations are highly underpredicted due to the implied use of LES filtering. However, good agreement can be found when the WMLES data are compared to the direct numerical simulation data filtered at the corresponding WMLES resolutions.
Quantification of shear stress in a meandering native topographic channel using a physical hydraulic model

Treesearch

Michael E. Ursic

2011-01-01

Current guidelines for predicting increases in shear stress in open-channel bends were developed from investigations that were primarily prismatic in cross section. This study provides possible increases in shear stress relative to approach flow conditions resulting from planimetric and topographic geometric features. Boundary shear stress estimates were determined by...
Evolution of allowable stresses in shear for lumber

Treesearch

Robert L. Ethington; William L. Galligan; Henry M. Montrey; Alan D. Freas

1979-01-01

This paper surveys research leading to allowable shear stress parallel to grain for lumber. In early flexure tests of lumber, some pieces failed in shear. The estimated shear stress at time of failure was generally lower than shear strength measured on small, clear, straight-grained specimens. This and other engineering observations gave rise to adjustments that...
An examination of the rheology of flocculated clay suspensions

NASA Astrophysics Data System (ADS)

Spearman, Jeremy

2017-04-01

A dense cohesive sediment suspension, sometimes referred to as fluid mud, is a thixotropic fluid with a true yield stress. Current rheological formulations struggle to reconcile the structural dynamics of cohesive sediment suspensions with the equilibrium behaviour of these suspensions across the range of concentrations and shear. This paper is concerned with establishing a rheological framework for the range of sediment concentrations from the yield point to Newtonian flow. The shear stress equation is based on floc fractal theory, put forward by Mills and Snabre (1988). This results in a Casson-like rheology equation. Additional structural dynamics is then added, using a theory on the self-similarity of clay suspensions proposed by Coussot (1995), giving an equation which has the ability to match the equilibrium and time-dependent viscous rheology of a wide range of suspensions of different concentration and mineralogy.
Analysis of shear test method for composite laminates

NASA Technical Reports Server (NTRS)

Bergner, H. W., Jr.; Davis, J. G., Jr.; Herakovich, C. T.

1977-01-01

An elastic plane stress finite element analysis of the stress distributions in four flat test specimens for in-plane shear response of composite materials subjected to mechanical or thermal loads is presented. The shear test specimens investigated include: slotted coupon, cross beam, losipescu, and rail shear. Results are presented in the form of normalized shear contour plots for all three in-plane stess components. It is shown that the cross beam, losipescu, and rail shear specimens have stress distributions which are more than adequate for determining linear shear behavior of composite materials. Laminate properties, core effects, and fixture configurations are among the factors which were found to influence the stress distributions.

Constitutive Behavior of Reinforced Concrete Membrane Elements under Tri-directional Shear

NASA Astrophysics Data System (ADS)

Labib, Moheb

The two-dimensional behavior of typical reinforced concrete (RC) structures has been extensively studied in the past several decades by investigating the constitutive behavior of full-scale reinforced concrete elements subjected to a bi-axial state of stress. In order to understand the true behavior of many large complex structures, the goal of this investigation is to develop new constitutive relationships for RC elements subjected to tri-directional shear stresses. Recently, additional out-of-plane jacks were installed on the panel tester at University of Houston so that concrete elements could be subjected to tri-directional shear stresses. This upgrade makes the panel tester the only one of its kind in the US that is capable of applying such combinations of stresses on full-scale reinforced concrete elements. This dissertation presents the details of the mounting and installation of the additional hydraulic jacks on the universal panel tester. The experimental program includes a series of seven reinforced concrete elements subjected to different combinations of in-plane and out-of-plane shear stresses. Increasing the applied out-of-plane shear stresses reduced the membrane shear strength of the elements. The effect of applying out-of-plane shear stresses on the in-plane shear strength was represented by modifying the softening coefficient in the compression stress strain curve of concrete struts. The modified model was able to capture the behavior and the ultimate capacity of the tested elements. The effect of the in-plane shear reinforcement ratio on the interaction between in-plane and out-of-plane shear stresses was evaluated. The model was implemented in the Finite Element package FEAP and was used to predict the ultimate capacity of many structures subjected to a combination of in-plane and out-of-plane shear stresses. The results of the analytical model were used to develop simplified design equations for members subjected to bi-directional shear loads. The applied out-of-plane shear load was resolved in two equal out-of-plane shear components to construct tri-directional shear interaction diagrams.
Strain-dependent activation energy of shear transformation in metallic glasses

NASA Astrophysics Data System (ADS)

Xu, Bin; Falk, Michael; Li, Jinfu; Kong, Lingti

2017-04-01

Shear transformation (ST) plays a decisive role in determining the mechanical behavior of metallic glasses, which is believed to be a stress-assisted thermally activated process. Understanding the dependence in its activation energy on the stress imposed on the material is of central importance to model the deformation process of metallic glasses and other amorphous solids. Here a theoretical model is proposed to predict the variation of the minimum energy path (MEP) associated with a particular ST event upon further deformation. Verification based on atomistic simulations and calculations are also conducted. The proposed model reproduces the MEP and activation energy of an ST event under different imposed macroscopic strains based on a known MEP at a reference strain. Moreover, an analytical approach is proposed based on the atomistic calculations, which works well when the stress varies linearity along the MEP. These findings provide necessary background for understanding the activation processes and, in turn, the mechanical behavior of metallic glasses.
Fluid shear stress primes mouse embryonic stem cells for differentiation in a self-renewing environment via heparan sulfate proteoglycans transduction

PubMed Central

Toh, Yi-Chin; Voldman, Joel

2011-01-01

Shear stress is a ubiquitous environmental cue experienced by stem cells when they are being differentiated or expanded in perfusion cultures. However, its role in modulating self-renewing stem cell phenotypes is unclear, since shear is usually only studied in the context of cardiovascular differentiation. We used a multiplex microfluidic array, which overcomes the limitations of macroperfusion systems in shear application throughput and precision, to initiate a comprehensive, quantitative study of shear effects on self-renewing mouse embryonic stem cells (mESCs), where shear stresses varying by >1000 times (0.016–16 dyn/cm2) are applied simultaneously. When compared with static controls in the presence or absence of a saturated soluble environment (i.e., mESC-conditioned medium), we ascertained that flow-induced shear stress specifically up-regulates the epiblast marker Fgf5. Epiblast-state transition in mESCs involves heparan sulfate proteoglycans (HSPGs), which have also been shown to transduce shear stress in endothelial cells. By disrupting (with sulfation inhibitors and heparinase) and partially reconstituting (with heparin) HSPG function, we show that mESCs also mechanically sense shear stress via HSPGs to modulate Fgf5 expression. This study demonstrates that self-renewing mESCs possess the molecular machinery to sense shear stress and provides quantitative shear application benchmarks for future scalable stem cell culture systems.—Toh, Y.-C., Voldman, J. Fluid shear stress primes mouse embryonic stem cells for differentiation in a self-renewing environment via heparan sulfate proteoglycans transduction. PMID:21183594
How shear increments affect the flow production branching ratio in CSDX

NASA Astrophysics Data System (ADS)

Li, J. C.; Diamond, P. H.

2018-06-01

The coupling of turbulence-driven azimuthal and axial flows in a linear device absent magnetic shear (Controlled Shear Decorrelation Experiment) is investigated. In particular, we examine the apportionment of Reynolds power between azimuthal and axial flows, and how the azimuthal flow shear affects axial flow generation and saturation by drift wave turbulence. We study the response of the energy branching ratio, i.e., ratio of axial and azimuthal Reynolds powers, PzR/PyR , to incremental changes of azimuthal and axial flow shears. We show that increasing azimuthal flow shear decreases the energy branching ratio. When axial flow shear increases, this ratio first increases but then decreases to zero. The axial flow shear saturates below the threshold for parallel shear flow instability. The effects of azimuthal flow shear on the generation and saturation of intrinsic axial flows are analyzed. Azimuthal flow shear slows down the modulational growth of the seed axial flow shear, and thus reduces intrinsic axial flow production. Azimuthal flow shear reduces both the residual Reynolds stress (of axial flow, i.e., ΠxzR e s ) and turbulent viscosity ( χzDW ) by the same factor |⟨vy⟩'|-2Δx-2Ln-2ρs2cs2 , where Δx is the distance relative to the reference point where ⟨vy⟩=0 in the plasma frame. Therefore, the stationary state axial flow shear is not affected by azimuthal flow shear to leading order since ⟨vz⟩'˜ΠxzR e s/χzDW .
Human endothelial cell responses to cardiovascular inspired pulsatile shear stress

NASA Astrophysics Data System (ADS)

Watson, Matthew; Baugh, Lauren; Black, Lauren, III; Kemmerling, Erica

2016-11-01

It is well established that hemodynamic shear stress regulates blood vessel structure and the development of vascular pathology. This process can be studied via in vitro models of endothelial cell responses to pulsatile shear stress. In this study, a macro-scale cone and plate viscometer was designed to mimic various shear stress waveforms found in the body and apply these stresses to human endothelial cells. The device was actuated by a PID-controlled DC gear-motor. Cells were exposed to 24 hours of pulsatile shear and then imaged and stained to track their morphology and secretions. These measurements were compared with control groups of cells exposed to constant shear and no shear. The results showed that flow pulsatility influenced levels of secreted proteins such as VE-cadherin and neuroregulin IHC. Cell morphology was also influenced by flow pulsatility; in general cells exposed to pulsatile shear stress developed a higher aspect ratio than cells exposed to no flow but a lower aspect ratio than cells exposed to steady flow.
Effect of intraplaque angiogenesis to atherosclerotic rupture-prone plaque induced by high shear stress in rabbit model

PubMed Central

Qiu, Juhui; Lei, Daoxi; Hu, Jianjun; Yin, Tieying; Zhang, Kang; Yu, Donghong

2017-01-01

Abstract Atherosclerotic prone-rupture plaque is mainly localized in the region of the entrance to the stenosis with high shear stress and the reasons are largely unknown. Our hypothesis is that such a distribution of cells in atherosclerotic plaque may depend on the angiogenesis. Silastic collars induced regions of high shear stress (20.68 ± 5.27 dynes/cm2) in the upstream flow and low shear stress (12.25 ± 1.28 dynes/cm2) in the downstream flow in carotid arteries. Compared with the low shear stress region, plaques in the high shear stress region showed more intraplaque haemorrhaging, less collagen and higher apoptotic rates of vascular smooth muscle cells; endothelial cells (ECs) in the high shear stress region were characterized with integrity and high endothelial nitric oxide synthase (eNOS) expression (1570.3 ± 345.5% vs 172.9 ± 49.9%). The number of intraplaque microvessels is very high in the high shear stress region (15 ± 1.8 n/mm2 vs 3.5 ± 0.4 n/mm2), and the microvessels in the plaque show ECs were abnormal, with membrane blebs, intracytoplasmic vacuoles and leukocyte infiltration. Our current study reveals that the integrity of the endothelium and the vulnerability of atherosclerotic plaques are simultaneously localized in high shear stress regions, and we provide evidence for the first time that microvessels in the intraplaque maybe responsible for rupture-prone plaque formation in the high shear stress region. PMID:28798867
Red blood cell deformability and aggregation behaviour in different animal species.

PubMed

Plasenzotti, R; Stoiber, B; Posch, M; Windberger, U

2004-01-01

Comparative animal studies showed the wide variation of whole blood and plasma viscosity, and erythrocyte aggregation among mammalian species. Whole blood viscosity and red blood cell aggregation is influenced by red cell fluidity. To evaluate differences in erythrocyte deformability in mammals, three species were investigated, whose erythrocytes have a different aggregation property: horse, as a species with high, dog with medium, and sheep with almost unmeasurable aggregation tendency. Erythrocyte deformability was tested ektacytometrically (Elongation Index [EI], LORCA, Mechatronics, Hoorn, Netherlands) at shear stresses from 0.30 to 53.06 Pa. Equine erythrocytes showed EI-values from 0.047 at low shear stress to 0.541 at high shear stress. The EI from dog's erythrocytes ranged from 0.035 to 0.595. Sheep's erythrocytes had an EI of 0.005 at low and 0.400 at high shear stress. Although it might be presumed from the aggregation property that horse had the highest EI among the three species, the EI of canine erythrocytes exceeded the value in horses by 10% at high shear stress. Further, equine erythrocytes started to deform at higher shear stresses (1.69 Pa) than did canine and ovine cells, whose EI increased continuously with increasing shear stress. At moderate shear stress (1-5 Pa) deformability was even higher in the sheep than in the horse. However, at shear stresses higher than 5.34 Pa, equine red cell elongation clearly exceeded the values of sheep. We conclude that erythrocyte elongation is different between the animal species, not clearly linked with the aggregation property, and that the degree of deformability at various shear stresses is species-specific.
Research on wall shear stress considering wall roughness when shear swirling flow vibration cementing

NASA Astrophysics Data System (ADS)

Cui, Zhihua; Ai, Chi; Feng, Fuping

2017-01-01

When shear swirling flow vibration cementing, the casing is revolving periodically and eccentrically, which leads to the annulus fluid in turbulent swirling flow state. The wall shear stress is more than that in laminar flow field when conventional cementing. The paper mainly studied the wall shear stress distribution on the borehole wall when shear swirling flow vibration cementing based on the finite volume method. At the same time, the wall roughness affected and changed the turbulent flow near the borehole wall and the wall shear stress. Based on the wall function method, the paper established boundary conditions considering the wall roughness and derived the formula of the wall shear stress. The results showed that the wall roughness significantly increases the wall shear stress. However, the larger the wall roughness, the greater the thickness of mud cake, which weakening the cementing strength. Considering the effects in a comprehensive way, it is discovered that the particle size of solid phase in drilling fluid is about 0.1 mm to get better cementing quality.
Shear flow of one-component polarizable fluid in a strong electric field

NASA Astrophysics Data System (ADS)

Sun, J. M.; Tao, R.

1996-04-01

A shear flow of one-component polarizable fluid in a strong electric field has a structural transition at a critical shear stress. When the shear stress is increased from zero up to the critical shear stress, the flow (in the x direction) has a flowing-chain (FC) structure, consisting of tilted or broken chains along the field (z direction). At the critical shear stress, the FC structure gives way to a flowing-hexagonal-layered (FHL) structure, consisting of several two-dimensional layers which are parallel to the x-z plane. Within one layer, particles form strings in the flow direction. Strings are constantly sliding over particles in strings right beneath. The effective viscosity drops dramatically at the structural change. As the shear stress reduces, the FHL structure persists even under a stress-free state if the thermal fluctuation is very weak. This structure change in the charging and discharging process produces a large hysteresis.
Effect of shear stress on the migration of hepatic stellate cells.

PubMed

Sera, Toshihiro; Sumii, Tateki; Fujita, Ryosuke; Kudo, Susumu

2018-01-01

When the liver is damaged, hepatic stellate cells (HSCs) can change into an activated, highly migratory state. The migration of HSCs may be affected by shear stress due not only to sinusoidal flow but also by the flow in the space of Disse because this space is filled with blood plasma. In this study, we evaluated the effects of shear stress on HSC migration in a scratch-wound assay with a parallel flow chamber. At regions upstream of the wound area, the migration was inhibited by 0.6 Pa and promoted by 2.0 Pa shear stress, compared to the static condition. The platelet-derived growth factor (PDGF)-BB receptor, PDGFR-β, was expressed in all conditions and the differences were not significant. PDGF increased HSC migration, except at 0.6 Pa shear stress, which was still inhibited. These results indicate that another molecular factor, such as PDGFR-α, may act to inhibit the migration under low shear stress. At regions downstream of the wound area, the migration was smaller under shear stress than under the static condition, although the expression of PDGFR-β was significantly higher. In particular, the migration direction was opposite to the wound area under high shear stress; therefore, migration might be influenced by the intercellular environment. Our results indicate that HSC migration was influenced by shear stress intensity and the intercellular environment.
Closed-form analysis of fiber-matrix interface stresses under thermo-mechanical loadings

NASA Technical Reports Server (NTRS)

Naik, Rajiv A.; Crews, John H., Jr.

1992-01-01

Closed form techniques for calculating fiber matrix (FM) interface stresses, using repeating square and diamond regular arrays, were presented for a unidirectional composite under thermo-mechanical loadings. An Airy's stress function micromechanics approach from the literature, developed for calculating overall composite moduli, was extended in the present study to compute FM interface stresses for a unidirectional graphite/epoxy (AS4/3501-6) composite under thermal, longitudinal, transverse, transverse shear, and longitudinal shear loadings. Comparison with finite element results indicate excellent agreement of the FM interface stresses for the square array. Under thermal and longitudinal loading, the square array has the same FM peak stresses as the diamond array. The square array predicted higher stress concentrations under transverse normal and longitudinal shear loadings than the diamond array. Under transverse shear loading, the square array had a higher stress concentration while the diamond array had a higher radial stress concentration. Stress concentration factors under transverse shear and longitudinal shear loadings were very sensitive to fiber volume fraction. The present analysis provides a simple way to calculate accurate FM interface stresses for both the square and diamond array configurations.
Shear-coupled grain-boundary migration dependence on normal strain/stress

NASA Astrophysics Data System (ADS)

Combe, N.; Mompiou, F.; Legros, M.

2017-08-01

In specific conditions, grain-boundary (GB) migration occurs in polycrystalline materials as an alternative vector of plasticity compared to the usual dislocation activity. The shear-coupled GB migration, the expected most efficient GB based mechanism, couples the GB motion to an applied shear stress. Stresses on GB in polycrystalline materials seldom have, however, a unique pure shear component. This work investigates the influence of a normal strain on the shear coupled migration of a Σ 13 (320 )[001 ] GB in a copper bicrystal using atomistic simulations. We show that the yield shear stress inducing the GB migration strongly depends on the applied normal stress. Beyond, the application of a normal stress on this GB qualitatively modifies the GB migration: while the Σ 13 (320 )[001 ] GB shear couples following the 〈110 〉 migration mode without normal stress, we report the observation of the 〈010 〉 mode under a sufficiently high tensile normal stress. Using the nudge elastic band method, we uncover the atomistic mechanism of this 〈010 〉 migration mode and energetically characterize it.
The dynamics of a shear band

NASA Astrophysics Data System (ADS)

Giarola, Diana; Capuani, Domenico; Bigoni, Davide

2018-03-01

A shear band of finite length, formed inside a ductile material at a certain stage of a continued homogeneous strain, provides a dynamic perturbation to an incident wave field, which strongly influences the dynamics of the material and affects its path to failure. The investigation of this perturbation is presented for a ductile metal, with reference to the incremental mechanics of a material obeying the J2-deformation theory of plasticity (a special form of prestressed, elastic, anisotropic, and incompressible solid). The treatment originates from the derivation of integral representations relating the incremental mechanical fields at every point of the medium to the incremental displacement jump across the shear band faces, generated by an impinging wave. The boundary integral equations (under the plane strain assumption) are numerically approached through a collocation technique, which keeps into account the singularity at the shear band tips and permits the analysis of an incident wave impinging a shear band. It is shown that the presence of the shear band induces a resonance, visible in the incremental displacement field and in the stress intensity factor at the shear band tips, which promotes shear band growth. Moreover, the waves scattered by the shear band are shown to generate a fine texture of vibrations, parallel to the shear band line and propagating at a long distance from it, but leaving a sort of conical shadow zone, which emanates from the tips of the shear band.
Localized stress fluctuations drive shear thickening in dense suspensions

NASA Astrophysics Data System (ADS)

Rathee, Vikram; Blair, Daniel L.; Urbach, Jeffrey S.

2017-08-01

Dense particulate suspensions exhibit a dramatic increase in average viscosity above a critical, material-dependent shear stress. This thickening changes from continuous to discontinuous as the concentration is increased. Using direct measurements of spatially resolved surface stresses in the continuous thickening regime, we report the existence of clearly defined dynamic localized regions of substantially increased stress that appear intermittently at stresses above the critical stress. With increasing applied stress, these regions occupy an increasing fraction of the system, and the increase accounts quantitatively for the observed shear thickening. The regions represent high-viscosity fluid phases, with a size determined by the distance between the shearing surfaces and a viscosity that is nearly independent of shear rate but that increases rapidly with concentration. Thus, we find that continuous shear thickening arises from increasingly frequent localized discontinuous transitions between distinct fluid phases with widely differing viscosities.
Repetitive Supra-Physiological Shear Stress Impairs Red Blood Cell Deformability and Induces Hemolysis.

PubMed

Horobin, Jarod T; Sabapathy, Surendran; Simmonds, Michael J

2017-11-01

The supra-physiological shear stress that blood is exposed to while traversing mechanical circulatory assist devices affects the physical properties of red blood cells (RBCs), impairs RBC deformability, and may induce hemolysis. Previous studies exploring RBC damage following exposure to supra-physiological shear stress have employed durations exceeding clinical instrumentation, thus we explored changes in RBC deformability following exposure to shear stress below the reported "hemolytic threshold" using shear exposure durations per minute (i.e., duty-cycles) reflective of that employed by circulatory assist devices. Blood collected from 20 male donors, aged 18-38 years, was suspended in a viscous medium and exposed to an intermittent shear stress protocol of 1 s at 100 Pa, every 60 s for 60 duty-cycles. During the remaining 59 s/min, the cells were left at stasis until the subsequent duty-cycle commenced. At discrete time points (15/30/45/60 duty-cycles), an ektacytometer measured RBC deformability immediately after shear exposure at 100 Pa. Plasma-free hemoglobin, a measurement of hemolysis, was quantified via spectrophotometry. Supra-physiological shear stress impaired RBC properties, as indicated by: (1) decreased maximal elongation of RBCs at infinite shear stress following 15 duty-cycles (P <0.05); (2) increased real-time RBC deformability during application of the supra-physiological shear stress protocol (100 Pa) following exposure to 1 duty-cycle (F (1.891, 32.15) = 12.21, P = 0.0001); and (3) increased plasma-free hemoglobin following 60 duty-cycles (P < 0.01). The present study indicates that exposure of RBCs to short-term, repeated supra-physiological shear stress, impairs RBC deformability, with the extent of impairment exacerbated with each duty-cycle, and ultimately precipitates hemolysis. © 2017 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.
Influence of polymer charge on the shear yield stress of silica aggregated with adsorbed cationic polymers.

PubMed

Zhou, Ying; Yu, Hai; Wanless, Erica J; Jameson, Graeme J; Franks, George V

2009-08-15

Flocs were produced by adding three cationic polymers (10% charge density, 3.0x10(5) g/mol molecular weight; 40% charge density, 1.1x10(5) g/mol molecular weight; and 100% charge density, 1.2x10(5) g/mol molecular weight) to 90 nm diameter silica particles. The shear yield stresses of the consolidated sediment beds from settled and centrifuged flocs were determined via the vane technique. The polymer charge density plays an important role in influencing the shear yield stresses of sediment beds. The shear yield stresses of sediment beds from flocs induced by the 10% charged polymer were observed to increase with an increase in polymer dose, initial solid concentration and background electrolyte concentration at all volume fractions. In comparison, polymer dose has a marginal effect on the shear yield stresses of sediment beds from flocs induced by the 40% and 100% charged polymers. The shear yield stresses of sediments from flocs induced by the 40% charged polymer are independent of salt concentration whereas the addition of salt decreases the shear yield stresses of sediments from flocs induced by the 100% charged polymer. When flocculated at the optimum dose for each polymer (12 mg/g silica for the 10% charged polymer at 0.03 M NaCl, 12 mg/g for 40% and 2 mg/g for 100%), shear yield stress increases as polymer charge increases. The effects observed are related to the flocculation mechanism (bridging, patch attraction or charge neutralisation) and the magnitude of the adhesive force. Comparison of shear and compressive yield stresses show that the network is only slightly weaker in shear than in compression. This is different than many other systems (mainly salt and pH coagulation) which have shear yield stress much less than compressive yield stress. The existing models relating the power law exponent of the volume fraction dependence of the shear yield stress to the network fractal structure are not satisfactory to predict all the experimental behaviour.
An analysis of the characteristics of rough bed turbulent shear stresses in an open channel

NASA Astrophysics Data System (ADS)

Keshavarzy, A.; Ball, J. E.

1997-06-01

Entrainment of sediment particles from channel beds into the channel flow is influenced by the characteristics of the flow turbulence which produces stochastic shear stress fluctuations at the bed. Recent studies of the structure of turbulent flow has recognized the importance of bursting processes as important mechanisms for the transfer of momentum into the laminar boundary layer. Of these processes, the sweep event has been recognized as the most important bursting event for entrainment of sediment particles as it imposes forces in the direction of the flow resulting in movement of particles by rolling, sliding and occasionally saltating. Similarly, the ejection event has been recognized as important for sediment transport since these events maintain the sediment particles in suspension. In this study, the characteristics of bursting processes and, in particular, the sweep event were investigated in a flume with a rough bed. The instantaneous velocity fluctuations of the flow were measured in two-dimensions using a small electromagnetic velocity meter and the turbulent shear stresses were determined from these velocity fluctuations. It was found that the shear stress applied to the sediment particles on the bed resulting from sweep events depends on the magnitude of the turbulent shear stress and its probability distribution. A statistical analysis of the experimental data was undertaken and it was found necessary to apply a Box-Cox transformation to transform the data into a normally distributed sample. This enabled determination of the mean shear stress, angle of action and standard error of estimate for sweep and ejection events. These instantaneous shear stresses were found to be greater than the mean flow shear stress and for the sweep event to be approximately 40 percent greater near the channel bed. Results from this analysis suggest that the critical shear stress determined from Shield's diagram is not sufficient to predict the initiation of motion due to its use of the temporal mean shear stress. It is suggested that initiation of particle motion, but not continuous motion, can occur earlier than suggested by Shield's diagram due to the higher shear stresses imposed on the particles by the stochastic shear stresses resulting from turbulence within the flow.
Low-level shear stress promotes migration of liver cancer stem cells via the FAK-ERK1/2 signalling pathway.

PubMed

Sun, Jinghui; Luo, Qing; Liu, Lingling; Song, Guanbin

2018-07-28

Cancer stem cells (CSCs) are a small subpopulation of tumour cells that have been proposed to be responsible for cancer initiation, chemotherapy resistance and cancer recurrence. Shear stress activated cellular signalling is involved in cellular migration, proliferation and differentiation. However, little is known about the effects of shear stress on the migration of liver cancer stem cells (LCSCs). Here, we studied the effects of shear stress that are generated from a parallel plated flow chamber system, on LCSC migration and the activation of focal adhesion kinase (FAK) and extracellular signal regulated kinase1/2 (ERK1/2), using transwell assay and western blot, respectively. We found that 2 dyne/cm 2 shear stress loading for 6 h promotes LCSC migration and activation of the FAK and ERK1/2 signalling pathways, whereas treatment with the FAK phosphorylation inhibitor PF573228 or the ERK1/2 phosphorylation inhibitor PD98059 suppressed the shear stress-promoted migration, indicating the involvement of FAK and ERK1/2 activation in shear stress-induced LCSC migration. Additionally, atomic force microscopy (AFM) analysis showed that shear stress lowers LCSC stiffness via the FAK and ERK1/2 pathways, suggesting that the mechanism by which shear stress promotes LCSC migration might partially be responsible for the decrease in cell stiffness. Further experiments focused on the role of the actin cytoskeleton, demonstrating that the F-actin filaments in LCSCs are less well-defined after shear stress treatment, providing an explanation for the reduction in cell stiffness and the promotion of cell migration. Overall, our study demonstrates that shear stress promotes LCSC migration through the activation of the FAK-ERK1/2 signalling pathways, which further results in a reduction of organized actin and softer cell bodies. Copyright © 2018 Elsevier B.V. All rights reserved.
Smoothing and roughening of slip surfaces in direct shear experiments

NASA Astrophysics Data System (ADS)

Sagy, Amir; Badt, Nir; Hatzor, Yossef H.

2015-04-01

Faults in the upper crust contain discrete slip surfaces which have absorbed a significant part of the shear displacement along them. Field measurements demonstrate that these surfaces are rough at all measurable scales and indicate that surfaces of relatively large-slip faults are statistically smoother than those of small-slip faults. However, post faulting and surface erosion process that might affect the geometry of outcrops cannot be discounted in such measurements. Here we present experimental results for the evolution of shear surface topography as function of slip distance and normal stress in direct shear experiments. A single prismatic fine grain limestone block is first fractured in tension mode using the four-point bending test methodology and then the fracture surface topography is scanned using a laser profilometer. We then shear the obtained tensile fracture surfaces in direct shear, ensuring the original fracture surfaces are in a perfectly matching configuration at the beginning of the shear test. First, shearing is conducted to distances varying from 5 to 15 mm under constant normal stress of 2MPa and a constant displacement rate of 0.05 mm/s using two closed-loop servo controlled hydraulic pistons, supplying normal and shear forces (Davidesko et al., 2014). In the tested configuration peak shear stress is typically attained after a shear displacement of about 2-3 mm, beyond which lower shear stress is required to continue shearing at the preset displacement rate of 0.05 mm/s as is typical for initially rough joints. Following some initial compression the interface begins to dilate and continues to do so until the end of the test. The sheared tensile fracture surface is then scanned again and the geometrical evolution, in term of RMS roughness and power spectral density (PSD) is analyzed. We show that shearing smooth the surface along all our measurements scales. The roughness ratio, measured by initial PSD / final PSD for each wavelength, increases as a function of slip amount. The roughness measured after slip can be fitted by a power-law similar to that of the initial tensile surface. In the next series of experiments a similar procedure is applied when the roughness evolution is measured as a function of increasing normal stress for a fixed displacement amount of 10 mm. While samples sheared under a constant normal stress of 5 MPa generated surface smoothing, shearing under normal stress of 7.5 MPa to 15 MPa exhibited surface roughening at the measured range of scales. We find that roughening is correlated with the attained peak shear stress values, stress drop (peak shear stress minus residual shear stress) and with wear accumulation, a novel measurement procedure of which is developed here. Analysis of the sheared samples shows that roughening is generated by sets of dense fractures that significantly damaged the sample in the immediate proximity to large asperities. This roughening is related to penetrative damage during transient wear in rough surfaces.
Surface temperatures and glassy state investigations in tribology

NASA Technical Reports Server (NTRS)

Bair, S.; Winer, W. O.

1979-01-01

The limiting shear stress shear rheological model was applied to property measurements pursuant to the use of the constitutive equation and the application of the constitutive equation to elastrohydrodynamic (EHD) traction. Experimental techniques were developed to subject materials to isothermal compression which is similar to the history the materials were subjected to in EHD contacts. In addition, an apparatus was developed for measuring the shear stress-strain behavior of solid lubricating materials. Four commercially available materials were examined under pressure. They exhibit elastic and limiting shear stress behavior similar to that of liquid lubricants. The application of the limiting shear stress model to traction predictions was extended employing the primary materials properties measured in the laboratory. The shear rheological model was also applied to a Grubin-like EHD inlet analysis for predicting film thicknesses when employing the limiting shear stress model material behavior.

Laboratory observations of artificial sand and oil agglomerates

USGS Publications Warehouse

Jenkins, Robert L.; Dalyander, P. Soupy; Penko, Allison; Long, Joseph W.

2018-04-27

Sand and oil agglomerates (SOAs) form when weathered oil reaches the surf zone and combines with suspended sediments. The presence of large SOAs in the form of thick mats (up to 10 centimeters [cm] in height and up to 10 square meters [m2] in area) and smaller SOAs, sometimes referred to as surface residual balls (SRBs), may lead to the re-oiling of beaches previously affected by an oil spill. A limited number of numerical modeling and field studies exist on the transport and dynamics of centimeter-scale SOAs and their interaction with the sea floor. Numerical models used to study SOAs have relied on shear-stress formulations to predict incipient motion. However, uncertainty exists as to the accuracy of applying these formulations, originally developed for sand grains in a uniformly sorted sediment bed, to larger, nonspherical SOAs. In the current effort, artificial sand and oil agglomerates (aSOAs) created with the size, density, and shape characteristics of SOAs were studied in a small-oscillatory flow tunnel. These experiments expanded the available data on SOA motion and interaction with the sea floor and were used to examine the applicability of shear-stress formulations to predict SOA mobility. Data collected during these two sets of experiments, including photographs, video, and flow velocity, are presented in this report, along with an analysis of shear-stress-based formulations for incipient motion. The results showed that shear-stress thresholds for typical quartz sand predicted the incipient motion of aSOAs with 0.5–1.0-cm diameters, but were inaccurate for aSOAs with larger diameters (>2.5 cm). This finding implies that modified parameterizations of incipient motion may be necessary under certain combinations of aSOA characteristics and environmental conditions.
Shape optimization of shear fracture specimen considering plastic anisotropy

NASA Astrophysics Data System (ADS)

Zhang, S.; Yoon, J. W.; Lee, S.; Lou, Y.

2017-10-01

It is important to fabricate fracture specimens with minimum variation of triaxiality in order to characterize the failure behaviors experimentally. Fracture in ductile materials is usually calibrated by uniaxial tensile, shear and plane strain tests. However, it is often observed that triaxiality for shear specimen changes severely during shear fracture test. The nonlinearity of triaxiality is most critical for shear test. In this study, a simple in-plane shear specimen is optimized by minimizing the variation of stress triaxiality in the shear zone. In the optimization, the Hill48 and Yld2000-2d criteria are employed to model the anisotropic plastic deformation of an aluminum alloy of 6k21. The evolution of the stress triaxiality of the optimized shear specimen is compared with that of the initial design of the shear specimen. The comparison reveals that the stress triaxiality changes much less for the optimized shear specimen than the evolution of the stress triaxiality with the original design of the shear specimen.
Shear stress and the endothelial transport barrier.

PubMed

Tarbell, John M

2010-07-15

The shear stress of flowing blood on the surfaces of endothelial cells that provide the barrier to transport of solutes and water between blood and the underlying tissue modulates the permeability to solutes and the hydraulic conductivity. This review begins with a discussion of transport pathways across the endothelium and then considers the experimental evidence from both in vivo and in vitro studies that shows an influence of shear stress on endothelial transport properties after both acute (minutes to hours) and chronic (hours to days) changes in shear stress. Next, the effects of shear stress on individual transport pathways (tight junctions, adherens junctions, vesicles and leaky junctions) are described, and this information is integrated with the transport experiments to suggest mechanisms controlling both acute and chronic responses of transport properties to shear stress. The review ends with a summary of future research challenges.
Wall Shear Stress, Wall Pressure and Near Wall Velocity Field Relationships in a Whirling Annular Seal

NASA Technical Reports Server (NTRS)

Morrison, Gerald L.; Winslow, Robert B.; Thames, H. Davis, III

1996-01-01

The mean and phase averaged pressure and wall shear stress distributions were measured on the stator wall of a 50% eccentric annular seal which was whirling in a circular orbit at the same speed as the shaft rotation. The shear stresses were measured using flush mounted hot-film probes. Four different operating conditions were considered consisting of Reynolds numbers of 12,000 and 24,000 and Taylor numbers of 3,300 and 6,600. At each of the operating conditions the axial distribution (from Z/L = -0.2 to 1.2) of the mean pressure, shear stress magnitude, and shear stress direction on the stator wall were measured. Also measured were the phase averaged pressure and shear stress. These data were combined to calculate the force distributions along the seal length. Integration of the force distributions result in the net forces and moments generated by the pressure and shear stresses. The flow field inside the seal operating at a Reynolds number of 24,000 and a Taylor number of 6,600 has been measured using a 3-D laser Doppler anemometer system. Phase averaged wall pressure and wall shear stress are presented along with phase averaged mean velocity and turbulence kinetic energy distributions located 0.16c from the stator wall where c is the seal clearance. The relationships between the velocity, turbulence, wall pressure and wall shear stress are very complex and do not follow simple bulk flow predictions.
Structure of high and low shear-stress events in a turbulent boundary layer

NASA Astrophysics Data System (ADS)

Gomit, G.; de Kat, R.; Ganapathisubramani, B.

2018-01-01

Simultaneous particle image velocimetry (PIV) and wall-shear-stress sensor measurements were performed to study structures associated with shear-stress events in a flat plate turbulent boundary layer at a Reynolds number Reτ≈4000 . The PIV field of view covers 8 δ (where δ is the boundary layer thickness) along the streamwise direction and captures the entire boundary layer in the wall-normal direction. Simultaneously, wall-shear-stress measurements that capture the large-scale fluctuations were taken using a spanwise array of hot-film skin-friction sensors (spanning 2 δ ). Based on this combination of measurements, the organization of the conditional wall-normal and streamwise velocity fluctuations (u and v ) and of the Reynolds shear stress (-u v ) can be extracted. Conditional averages of the velocity field are computed by dividing the histogram of the large-scale wall-shear-stress fluctuations into four quartiles, each containing 25% of the occurrences. The conditional events corresponding to the extreme quartiles of the histogram (positive and negative) predominantly contribute to a change of velocity profile associated with the large structures and in the modulation of the small scales. A detailed examination of the Reynolds shear-stress contribution related to each of the four quartiles shows that the flow above a low wall-shear-stress event carries a larger amount of Reynolds shear stress than the other quartiles. The contribution of the small and large scales to this observation is discussed based on a scale decomposition of the velocity field.
Role of Wall Shear Stress in Cryptosporidium parvum Oocyst Attachment to Environmental Biofilms.

PubMed

Luo, Xia; Jedlicka, Sabrina S; Jellison, Kristen L

2017-12-15

This study investigated Cryptosporidium parvum oocyst deposition onto biofilms as a function of shear stress under laminar or turbulent flow. Annular rotating bioreactors were used to grow stabilized stream biofilms at shear stresses ranging from 0.038 to 0.46 Pa. These steady-state biofilms were then used to assess the impact of hydrodynamic conditions on C. parvum oocyst attachment. C. parvum deposition onto biofilms followed a pseudo-second-order model under both laminar (after a lag phase) and turbulent flows. The total number of oocysts attached to the biofilm at steady state decreased as the hydrodynamic wall shear stress increased. The oocyst deposition rate constant increased with shear stress but decreased at high shear, suggesting that increasing wall shear stress results in faster attachment of Cryptosporidium due to higher mass transport until the shear forces exceed a critical limit that prevents oocyst attachment. These data show that oocyst attachment in the short and long term are impacted differently by shear: higher shear (to a certain limit) may be associated with faster initial oocyst attachment, but lower shear is associated with greater numbers of oocysts attached at equilibrium. IMPORTANCE This research provides experimental evidence to demonstrate that shear stress plays a critical role in protozoan-pathogen transport and deposition in environmental waters. The data presented in this work expand scientific understanding of Cryptosporidium attachment and fate, which will further influence the development of timely and accurate sampling strategies, as well as advanced water treatment technologies, to target protozoan pathogens in surface waters that serve as municipal drinking water sources. Copyright © 2017 American Society for Microbiology.
Triglyceride glucose index and common carotid wall shear stress.

PubMed

Tripolino, Cesare; Irace, Concetta; Scavelli, Faustina B; de Franceschi, Maria S; Esposito, Teresa; Carallo, Claudio; Gnasso, Agostino

2014-02-01

Alterations in wall shear stress contribute to both clinical and subclinical atherosclerosis. Several conditions such as hypertension, diabetes, and obesity can impair shear stress, but the role of insulin resistance has never been investigated. The present study was designed to investigate whether insulin resistance assessed by TyG Index associates with wall shear stress in the common carotid artery. One hundred six individuals were enrolled. Blood pressure, lipids, glucose, and cigarette smoking were evaluated. TyG Index was calculated as log[fasting triglycerides × fasting glucose / 2]. Subjects underwent blood viscosity measurement and echo-Doppler evaluation of carotid arteries to calculate wall shear stress. The association between TyG Index and carotid wall shear stress was assessed by simple and multiple regression analyses. TyG Index was significantly and inversely associated with carotid wall shear stress both in simple (r = -0.44, P < 0.001) and multiple regression analyses accounting for age, sex, and major cardiovascular risk factors. The association was further confirmed after exclusion of subjects with diabetes, dyslipidemia, fasting blood glucose greater than 100 mg/dL, and triglycerides greater than 150 mg/dL. The present findings suggest that increasing insulin resistance, as assessed by TyG Index, associates with atherosclerosis-prone shear stress reduction in the common carotid artery.
Deformation and Stress Response of Carbon Nanotubes/UHMWPE Composites under Extensional-Shear Coupling Flow

NASA Astrophysics Data System (ADS)

Wang, Junxia; Cao, Changlin; Yu, Dingshan; Chen, Xudong

2018-02-01

In this paper, the effect of varying extensional-shear couple loading on deformation and stress response of Carbon Nanotubes/ ultra-high molecular weight polyethylene (CNTs/UHMWPE) composites was investigated using finite element numerical simulation, with expect to improve the manufacturing process of UHMWPE-based composites with reduced stress and lower distortion. When applying pure extensional loading and pure X-Y shear loading, it was found that the risk of a structural breakage greatly rises. For identifying the coupling between extensional and shear loading, distinct generations of force loading were defined by adjusting the magnitude of extensional loading and X-Y shear loading. It was shown that with the decrement of X-Y shear loading the deformation decreases obviously where the maximal Mises stress in Z-direction at 0.45 m distance is in the range from 24 to 10 MPa and the maximal shear stress at 0.61 m distance is within the range from 0.9 to 0.3 MPa. In addition, all the stresses determined were clearly below the yield strength of CNTs/UHMWPE composites under extensional-shear couple loading.
Human brain microvascular endothelial cells resist elongation due to shear stress.

PubMed

Reinitz, Adam; DeStefano, Jackson; Ye, Mao; Wong, Andrew D; Searson, Peter C

2015-05-01

Endothelial cells in straight sections of vessels are known to elongate and align in the direction of flow. This phenotype has been replicated in confluent monolayers of bovine aortic endothelial cells and human umbilical vein endothelial cells (HUVECs) in cell culture under physiological shear stress. Here we report on the morphological response of human brain microvascular endothelial cells (HBMECs) in confluent monolayers in response to shear stress. Using a microfluidic platform we image confluent monolayers of HBMECs and HUVECs under shear stresses up to 16 dyne cm(-2). From live-cell imaging we quantitatively analyze the cell morphology and cell speed as a function of time. We show that HBMECs do not undergo a classical transition from cobblestone to spindle-like morphology in response to shear stress. We further show that under shear stress, actin fibers are randomly oriented in the cells indicating that there is no cytoskeletal remodeling. These results suggest that HBMECs are programmed to resist elongation and alignment under shear stress, a phenotype that may be associated with the unique properties of the blood-brain barrier. Copyright © 2015 Elsevier Inc. All rights reserved.
Two-axis direct fluid shear stress sensor

NASA Technical Reports Server (NTRS)

Bajikar, Sateesh (Inventor); Scott, Michael A. (Inventor); Adcock, Edward E. (Inventor)

2011-01-01

A micro sized multi-axis semiconductor skin friction/wall shear stress induced by fluid flow. The sensor design includes a shear/strain transduction gimble connected to a force collecting plate located at the flow boundary surface. The shear force collecting plate is interconnected by an arm to offset the tortional hinges from the fluid flow. The arm is connected to the shear force collecting plate through dual axis torsional hinges with piezoresistive torsional strain gauges. These gauges are disposed on the tortional hinges and provide a voltage output indicative of applied shear stress acting on the force collection plate proximate the flow boundary surface. Offsetting the torsional hinges creates a force concentration and resolution structure that enables the generation of a large stress on the strain gauge from small shear stress, or small displacement of the collecting plate. The design also isolates the torsional sensors from exposure to the fluid flow.
Measurement of Wall Shear Stress in High Speed Air Flow Using Shear-Sensitive Liquid Crystal Coating.

PubMed

Zhao, Jisong

2018-05-17

Wall shear stress is an important quantity in fluid mechanics, but its measurement is a challenging task. An approach to measure wall shear stress vector distribution using shear-sensitive liquid crystal coating (SSLCC) is described. The wall shear stress distribution on the test surface beneath high speed jet flow is measured while using the proposed technique. The flow structures inside the jet flow are captured and the results agree well with the streakline pattern that was visualized using the oil-flow technique. In addition, the shock diamonds inside the supersonic jet flow are visualized clearly using SSLCC and the results are compared with the velocity contour that was measured using the particle image velocimetry (PIV) technique. The work of this paper demonstrates the application of SSLCC in the measurement/visualization of wall shear stress in high speed flow.
Measurement of Wall Shear Stress in High Speed Air Flow Using Shear-Sensitive Liquid Crystal Coating

PubMed Central

Zhao, Jisong

2018-01-01

Wall shear stress is an important quantity in fluid mechanics, but its measurement is a challenging task. An approach to measure wall shear stress vector distribution using shear-sensitive liquid crystal coating (SSLCC) is described. The wall shear stress distribution on the test surface beneath high speed jet flow is measured while using the proposed technique. The flow structures inside the jet flow are captured and the results agree well with the streakline pattern that was visualized using the oil-flow technique. In addition, the shock diamonds inside the supersonic jet flow are visualized clearly using SSLCC and the results are compared with the velocity contour that was measured using the particle image velocimetry (PIV) technique. The work of this paper demonstrates the application of SSLCC in the measurement/visualization of wall shear stress in high speed flow. PMID:29772822
Sublaminate analysis of interlaminar fracture in composites

NASA Technical Reports Server (NTRS)

Armanios, E. A.; Rehfield, L. W.

1986-01-01

A simple analysis method based upon a transverse shear deformation theory and a sublaminate approach is utilized to analyze a mixed-mode edge delamination specimen. The analysis provides closed form expressions for the interlaminar shear stresses ahead of the crack, the total energy release rate, and the energy release rate components. The parameters controlling the behavior are identified. The effect of specimen stacking sequence and delamination interface on the strain energy release rate components is investigated. Results are compared with a finite element simulation for reference. The simple nature of the method makes it suitable for preliminary design analyses which require a large number of configurations to be evaluated quickly and economically.
Effect of stress perturbation on frictional instability: an experimental study

NASA Astrophysics Data System (ADS)

Yuanmin, H.; Shengli, M.

2017-12-01

We have performed a series of frictional experiments with direct shear configuration of three granite blocks by using a servo-controlled biaxial loading machine. In the experiments, a small- amplitude sine wave is modulated to shear and normal loading in order to study the effects of stress perturbation on stick-slip instability. The main results are as follows. Under the constant average normal stress and the constant loading point velocity in shear direction, the sample shows regular stick-slip behavior. After the stress perturbation is modulated, the correlation between the timing of stick-slip events and the perturbation increases with increasing the perturbation amplitude, and stress drop and interval time of stick-slip events tend to be discrete. This results imply that the change in Coulomb stress caused by stress perturbation may obviously change not only the occurrence time of earthquakes but also the earthquake magnitude. Both shear and normal stress perturbation can affect the stick-slip behavior, shear stress perturbation can only change the driving stress along fault, while the normal stress perturbation can change the contact state of asperities on the fault, so it's effect is more obviously. The stress perturbation can obviously affect acoustic emission (AE) activity during fault friction, which can trigger some AE events so that AE activity before stick-slip becomes stronger and occurs earlier. The perturbation in shear stress is more evident than that in normal stress in affecting AE activity, so we should not only pay attention to the magnitude of Coulomb stress changes caused by the perturbation, but also try to distinguish the stress changes are the shear stress changes or the normal stress changes, when study the effect of stress perturbation on fault friction.
Determination of the Shear Stress Distribution in a Laminate from the Applied Shear Resultant--A Simplified Shear Solution

NASA Technical Reports Server (NTRS)

Bednarcyk, Brett A.; Aboudi, Jacob; Yarrington, Phillip W.

2007-01-01

The simplified shear solution method is presented for approximating the through-thickness shear stress distribution within a composite laminate based on laminated beam theory. The method does not consider the solution of a particular boundary value problem, rather it requires only knowledge of the global shear loading, geometry, and material properties of the laminate or panel. It is thus analogous to lamination theory in that ply level stresses can be efficiently determined from global load resultants (as determined, for instance, by finite element analysis) at a given location in a structure and used to evaluate the margin of safety on a ply by ply basis. The simplified shear solution stress distribution is zero at free surfaces, continuous at ply boundaries, and integrates to the applied shear load. Comparisons to existing theories are made for a variety of laminates, and design examples are provided illustrating the use of the method for determining through-thickness shear stress margins in several types of composite panels and in the context of a finite element structural analysis.
Shear stress and the endothelial transport barrier

PubMed Central

Tarbell, John M.

2010-01-01

The shear stress of flowing blood on the surfaces of endothelial cells that provide the barrier to transport of solutes and water between blood and the underlying tissue modulates the permeability to solutes and the hydraulic conductivity. This review begins with a discussion of transport pathways across the endothelium and then considers the experimental evidence from both in vivo and in vitro studies that shows an influence of shear stress on endothelial transport properties after both acute (minutes to hours) and chronic (hours to days) changes in shear stress. Next, the effects of shear stress on individual transport pathways (tight junctions, adherens junctions, vesicles and leaky junctions) are described, and this information is integrated with the transport experiments to suggest mechanisms controlling both acute and chronic responses of transport properties to shear stress. The review ends with a summary of future research challenges. PMID:20543206
Fluid shear stress sensitizes cancer cells to receptor-mediated apoptosis via trimeric death receptors

NASA Astrophysics Data System (ADS)

Mitchell, Michael J.; King, Michael R.

2013-01-01

Cancer metastasis, the process of cancer cell migration from a primary to distal location, typically leads to a poor patient prognosis. Hematogenous metastasis is initiated by intravasation of circulating tumor cells (CTCs) into the bloodstream, which are then believed to adhere to the luminal surface of the endothelium and extravasate into distal locations. Apoptotic agents such as tumor necrosis factor apoptosis-inducing ligand (TRAIL), whether in soluble ligand form or expressed on the surface of natural killer cells, have shown promise in treating CTCs to reduce the probability of metastasis. The role of hemodynamic shear forces in altering the cancer cell response to apoptotic agents has not been previously investigated. Here, we report that human colon cancer COLO 205 and prostate cancer PC-3 cells exposed to a uniform fluid shear stress in a cone-and-plate viscometer become sensitized to TRAIL-induced apoptosis. Shear-induced sensitization directly correlates with the application of fluid shear stress, and TRAIL-induced apoptosis increases in a fluid shear stress force- and time-dependent manner. In contrast, TRAIL-induced necrosis is not affected by the application fluid shear stress. Interestingly, fluid shear stress does not sensitize cancer cells to apoptosis when treated with doxorubicin, which also induces apoptosis in cancer cells. Caspase inhibition experiments reveal that shear stress-induced sensitization to TRAIL occurs via caspase-dependent apoptosis. These results suggest that physiological fluid shear forces can modulate receptor-mediated apoptosis of cancer cells in the presence of apoptotic agents.
Simulation of shear thickening in attractive colloidal suspensions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pednekar, Sidhant; Chun, Jaehun; Morris, Jeffrey F.

2017-01-01

The influence of attractive forces between particles under conditions of large particle volume fraction is addressed using numerical simulations which account for hydrodynamic, Brownian, conservative and frictional contact forces. The focus is on conditions for which a significant increase in the apparent viscosity at small shear rates, and possibly the development of a yield stress, is observed. The high shear rate behavior for Brownian suspensions has been shown in recent work [R. Mari, R. Seto, J. F. Morris & M. M. Denn, PNAS, 2015, 112, 15326-15330] to be captured by the inclusion of pairwise forces of two forms, one amore » contact frictional interaction and the second a repulsive force common in stabilized colloidal dispersions. Under such conditions, shear thickening is observed when shear stress is comparable to the sum of the Brownian stress and a characteristic stress based on the combination of interparticle force with kT the thermal energy. At sufficiently large volume fraction, this shear thickening can be very abrupt. Here it is shown that when attractive interactions are present with the noted forces, the shear thickening is obscured, as the viscosity shear thins with increasing shear rate, eventually descending from an infinite value (yield stress conditions) to a plateau at large stress; this plateau is at the same level as the large-shear rate viscosity found in the shear thickened state without attractive forces. It is shown that this behavior is consistent with prior observations in shear thickening suspensions modified to be attractive through depletion flocculation [V. Gopalakrishnan & C. F. Zukoski J. Rheol., 2004, 48, 1321-1344]. The contributions of the contact, attractive, and hydrodynamics forces to the bulk stress are presented, as are the contact networks found at different attractive strengths.« less
Evolution of crustal stress, pressure and temperature around shear zones during orogenic wedge formation: a 2D thermo-mechanical numerical study

NASA Astrophysics Data System (ADS)

Markus Schmalholz, Stefan; Jaquet, Yoann

2016-04-01

We study the formation of an orogenic wedge during lithospheric shortening with 2D numerical simulations. We consider a viscoelastoplastic rheology, thermo-mechanical coupling by shear heating and temperature-dependent viscosities, gravity and erosion. In the initial model configuration there is either a lateral temperature variation at the model base or a lateral variation in crustal thickness to generate slight stress variations during lithospheric shortening. These stress variations can trigger the formation of shear zones which are caused by thermal softening associated with shear heating. We do not apply any kind of strain softening, such as reduction of friction angle with progressive plastic strain. The first major shear zone that appears during shortening crosscuts the entire crust and initiates the asymmetric subduction/underthrusting of mainly the mechanically strong lower crust. After some deformation, the first shear zone in the upper crust is abandoned, the deformation propagates towards the foreland and a new shear zone forms only in the upper crust. The shear zone propagation occurs several times where new shear zones form in the upper crust and the mechanically strong top of the lower crust acts as detachment horizon. We calculate the magnitudes of the maximal and minimal principal stresses and of the mean stress (or dynamic pressure), and we record also the temperature for several marker points in the upper and lower crust. We analyse the evolution of stresses and temperature with burial depth and time. Deviatoric stresses (half the differential stress) in the upper crust are up to 200 MPa and associated shear heating in shear zones ranges between 40 - 80 °C. Lower crustal rocks remain either at the base of the orogenic wedge at depths of around 50 km or are subducted to depths of up to 120 km, depending on their position when the first shear zone formed. Largest deviatotric stresses in the strong part of the lower crust are about 1000 MPa and maximal shear heating in shear zones is approximately 200 °C. Marker points can migrate through the main shear zone in the lower crust which remains active throughout lithospheric shortening. Some pressure-temperature paths show an anti-clockwise evolution. The impact of various model parameters on the results is discussed as well as applications of the results to geological data.
Parametric study of the physical properties of hydrate-bearing sand, silt, and clay sediments: 2. Small-strain mechanical properties

USGS Publications Warehouse

Lee, J.Y.; Francisca, F.M.; Santamarina, J.C.; Ruppel, C.

2010-01-01

The small-strain mechanical properties (e.g., seismic velocities) of hydrate-bearing sediments measured under laboratory conditions provide reference values for calibration of logging and seismic exploration results acquired in hydrate-bearing formations. Instrumented cells were designed for measuring the compressional (P) and shear (S) velocities of sand, silts, and clay with and without hydrate and subject to vertical effective stresses of 0.01 to 2 MPa. Tetrahydrofuran (THF), which is fully miscible in water, was used as the hydrate former to permit close control over the hydrate saturation Shyd and to produce hydrate from dissolved phase, as methane hydrate forms in most natural marine settings. The results demonstrate that laboratory hydrate formation technique controls the pattern of P and S velocity changes with increasing Shyd and that the small-strain properties of hydrate-bearing sediments are governed by effective stress, δ'v and sediment specific surface. The S velocity increases with hydrate saturation owing to an increase in skeletal shear stiffness, particularly when hydrate saturation exceeds Shyd≈ 0.4. At very high hydrate saturations, the small strain shear stiffness is determined by the presence of hydrates and becomes insensitive to changes in effective stress. The P velocity increases with hydrate saturation due to the increases in both the shear modulus of the skeleton and the bulk modulus of pore-filling phases during fluid-to-hydrate conversion. Small-strain Poisson's ratio varies from 0.5 in soft sediments lacking hydrates to 0.25 in stiff sediments (i.e., subject to high vertical effective stress or having high Shyd). At Shyd ≥ 0.5, hydrate hinders expansion and the loss of sediment stiffness during reduction of vertical effective stress, meaning that hydrate-rich natural sediments obtained through pressure coring should retain their in situ fabric for some time after core retrieval if the cores are maintained within the hydrate stability field.

An Experimental Investigation of the Risk of Triggering Geological Disasters by Injection under Shear Stress

PubMed Central

Liu, Yixin; Xu, Jiang; Peng, Shoujian

2016-01-01

Fluid injection has been applied in many fields, such as hazardous waste deep well injection, forced circulation in geothermal fields, hydraulic fracturing, and CO2 geological storage. However, current research mainly focuses on geological data statistics and the dominating effects of pore pressure. There are only a few laboratory-conditioned studies on the role of drilling boreholes and the effect of injection pressure on the borehole wall. Through experimental phenomenology, this study examines the risk of triggering geological disasters by fluid injection under shear stress. We developed a new direct shear test apparatus, coupled Hydro-Mechanical (HM), to investigate mechanical property variations when an intact rock experienced step drilling borehole, fluid injection, and fluid pressure acting on the borehole and fracture wall. We tested the peak shear stress of sandstone under different experimental conditions, which showed that drilling borehole, water injection, and increased pore pressure led to the decrease in peak shear stress. Furthermore, as pore pressure increased, peak shear stress dispersion increased due to crack propagation irregularity. Because the peak shear stress changed during the fluid injection steps, we suggest that the risk of triggering geological disaster with injection under shear stress, pore, borehole, and fluid pressure should be considered. PMID:27929142
An Experimental Investigation of the Risk of Triggering Geological Disasters by Injection under Shear Stress.

PubMed

Liu, Yixin; Xu, Jiang; Peng, Shoujian

2016-12-08

Fluid injection has been applied in many fields, such as hazardous waste deep well injection, forced circulation in geothermal fields, hydraulic fracturing, and CO 2 geological storage. However, current research mainly focuses on geological data statistics and the dominating effects of pore pressure. There are only a few laboratory-conditioned studies on the role of drilling boreholes and the effect of injection pressure on the borehole wall. Through experimental phenomenology, this study examines the risk of triggering geological disasters by fluid injection under shear stress. We developed a new direct shear test apparatus, coupled Hydro-Mechanical (HM), to investigate mechanical property variations when an intact rock experienced step drilling borehole, fluid injection, and fluid pressure acting on the borehole and fracture wall. We tested the peak shear stress of sandstone under different experimental conditions, which showed that drilling borehole, water injection, and increased pore pressure led to the decrease in peak shear stress. Furthermore, as pore pressure increased, peak shear stress dispersion increased due to crack propagation irregularity. Because the peak shear stress changed during the fluid injection steps, we suggest that the risk of triggering geological disaster with injection under shear stress, pore, borehole, and fluid pressure should be considered.
Colors Of Liquid Crystals Used To Measure Surface Shear Stresses

NASA Technical Reports Server (NTRS)

Reda, D. C.; Muratore, J. J., Jr.

1996-01-01

Developmental method of mapping shear stresses on aerodynamic surfaces involves observation, at multiple viewing angles, of colors of liquid-crystal surface coats illuminated by white light. Report describing method referenced in "Liquid Crystals Indicate Directions Of Surface Shear Stresses" (ARC-13379). Resulting maps of surface shear stresses contain valuable data on magnitudes and directions of skin friction forces associated with surface flows; data used to refine mathematical models of aerodynamics for research and design purposes.
Wall shear stress estimates in coronary artery constrictions

NASA Technical Reports Server (NTRS)

Back, L. H.; Crawford, D. W.

1992-01-01

Wall shear stress estimates from laminar boundary layer theory were found to agree fairly well with the magnitude of shear stress levels along coronary artery constrictions obtained from solutions of the Navier Stokes equations for both steady and pulsatile flow. The relatively simple method can be used for in vivo estimates of wall shear stress in constrictions by using a vessel shape function determined from a coronary angiogram, along with a knowledge of the flow rate.
Formulating the shear stress distribution in circular open channels based on the Renyi entropy

NASA Astrophysics Data System (ADS)

Khozani, Zohreh Sheikh; Bonakdari, Hossein

2018-01-01

The principle of maximum entropy is employed to derive the shear stress distribution by maximizing the Renyi entropy subject to some constraints and by assuming that dimensionless shear stress is a random variable. A Renyi entropy-based equation can be used to model the shear stress distribution along the entire wetted perimeter of circular channels and circular channels with flat beds and deposited sediments. A wide range of experimental results for 12 hydraulic conditions with different Froude numbers (0.375 to 1.71) and flow depths (20.3 to 201.5 mm) were used to validate the derived shear stress distribution. For circular channels, model performance enhanced with increasing flow depth (mean relative error (RE) of 0.0414) and only deteriorated slightly at the greatest flow depth (RE of 0.0573). For circular channels with flat beds, the Renyi entropy model predicted the shear stress distribution well at lower sediment depth. The Renyi entropy model results were also compared with Shannon entropy model results. Both models performed well for circular channels, but for circular channels with flat beds the Renyi entropy model displayed superior performance in estimating the shear stress distribution. The Renyi entropy model was highly precise and predicted the shear stress distribution in a circular channel with RE of 0.0480 and in a circular channel with a flat bed with RE of 0.0488.
Estimates of stress drop and crustal tectonic stress from the 27 February 2010 Maule, Chile, earthquake: Implications for fault strength

USGS Publications Warehouse

Luttrell, K.M.; Tong, X.; Sandwell, D.T.; Brooks, B.A.; Bevis, M.G.

2011-01-01

The great 27 February 2010 Mw 8.8 earthquake off the coast of southern Chile ruptured a ???600 km length of subduction zone. In this paper, we make two independent estimates of shear stress in the crust in the region of the Chile earthquake. First, we use a coseismic slip model constrained by geodetic observations from interferometric synthetic aperture radar (InSAR) and GPS to derive a spatially variable estimate of the change in static shear stress along the ruptured fault. Second, we use a static force balance model to constrain the crustal shear stress required to simultaneously support observed fore-arc topography and the stress orientation indicated by the earthquake focal mechanism. This includes the derivation of a semianalytic solution for the stress field exerted by surface and Moho topography loading the crust. We find that the deviatoric stress exerted by topography is minimized in the limit when the crust is considered an incompressible elastic solid, with a Poisson ratio of 0.5, and is independent of Young's modulus. This places a strict lower bound on the critical stress state maintained by the crust supporting plastically deformed accretionary wedge topography. We estimate the coseismic shear stress change from the Maule event ranged from-6 MPa (stress increase) to 17 MPa (stress drop), with a maximum depth-averaged crustal shear-stress drop of 4 MPa. We separately estimate that the plate-driving forces acting in the region, regardless of their exact mechanism, must contribute at least 27 MPa trench-perpendicular compression and 15 MPa trench-parallel compression. This corresponds to a depth-averaged shear stress of at least 7 MPa. The comparable magnitude of these two independent shear stress estimates is consistent with the interpretation that the section of the megathrust fault ruptured in the Maule earthquake is weak, with the seismic cycle relieving much of the total sustained shear stress in the crust. Copyright 2011 by the American Geophysical Union.
Wrinkling of reinforced plates subjected to shear stresses

NASA Technical Reports Server (NTRS)

Seydel, Edgar

1931-01-01

An analysis is made here of the problem of long plates with transverse stiffeners subject to shear. A typical example would be a long Wagner beam. The shear stress is calculated at which the web wrinkles and shear stress becomes a maximum. The equation is solved for both a condition of free support and rigidity of support on the edges.
An investigation on near wall transport characteristics in an adiabatic upward gas-liquid two-phase slug flow

NASA Astrophysics Data System (ADS)

Zheng, Donghong; Che, Defu

2007-08-01

The near-wall transport characteristics, inclusive of mass transfer coefficient and wall shear stress, which have a great effect on gas-liquid two-phase flow induced internal corrosion of low alloy pipelines in vertical upward oil and gas mixing transport, have been both mechanistically and experimentally investigated in this paper. Based on the analyses on the hydrodynamic characteristics of an upward slug unit, the mass transfer in the near wall can be divided into four zones, Taylor bubble nose zone, falling liquid film zone, Taylor bubble wake zone and the remaining liquid slug zone; the wall shear stress can be divided into two zones, the positive wall shear stress zone associated with the falling liquid film and the negative wall shear stress zone associated with the liquid slug. Based on the conventional mass transfer and wall shear stress characteristics formulas of single phase liquid full-pipe turbulent flow, corrected normalized mass transfer coefficient formula and wall shear stress formula are proposed. The calculated results are in good agreement with the experimental data. The shear stress and the mass transfer coefficient in the near wall zone are increased with the increase of superficial gas velocity and decreased with the increase of superficial liquid velocity. The mass transfer coefficients in the falling liquid film zone and the wake zone of leading Taylor bubble are lager than those in the Taylor bubble nose zone and the remaining liquid slug zone, and the wall shear stress associated falling liquid film is larger than that associated the liquid slug. The mass transfer coefficient is within 10-3 m/s, and the wall shear stress below 103 Pa. It can be concluded that the alternate wall shear stress due to upward gas-liquid slug flow is considered to be the major cause of the corrosion production film fatigue cracking.
Wall shear stress in intracranial aneurysms and adjacent arteries☆

PubMed Central

Wang, Fuyu; Xu, Bainan; Sun, Zhenghui; Wu, Chen; Zhang, Xiaojun

2013-01-01

Hemodynamic parameters play an important role in aneurysm formation and growth. However, it is difficult to directly observe a rapidly growing de novo aneurysm in a patient. To investigate possible associations between hemodynamic parameters and the formation and growth of intracranial aneurysms, the present study constructed a computational model of a case with an internal carotid artery aneurysm and an anterior communicating artery aneurysm, based on the CT angiography findings of a patient. To simulate the formation of the anterior communicating artery aneurysm and the growth of the internal carotid artery aneurysm, we then constructed a model that virtually removed the anterior communicating artery aneurysm, and a further two models that also progressively decreased the size of the internal carotid artery aneurysm. Computational simulations of the fluid dynamics of the four models were performed under pulsatile flow conditions, and wall shear stress was compared among the different models. In the three aneurysm growth models, increasing size of the aneurysm was associated with an increased area of low wall shear stress, a significant decrease in wall shear stress at the dome of the aneurysm, and a significant change in the wall shear stress of the parent artery. The wall shear stress of the anterior communicating artery remained low, and was significantly lower than the wall shear stress at the bifurcation of the internal carotid artery or the bifurcation of the middle cerebral artery. After formation of the anterior communicating artery aneurysm, the wall shear stress at the dome of the internal carotid artery aneurysm increased significantly, and the wall shear stress in the upstream arteries also changed significantly. These findings indicate that low wall shear stress may be associated with the initiation and growth of aneurysms, and that aneurysm formation and growth may influence hemodynamic parameters in the local and adjacent arteries. PMID:25206394
The effects of non-Newtonian viscosity on the deformation of red blood cells in a shear flow

NASA Astrophysics Data System (ADS)

Sesay, Juldeh

2005-11-01

The analyses of the effects of non-Newtonian viscosity on the membrane of red blood cells (RBCs) suspended in a shear flow are presented. The specific objective is to investigate the mechanical deformation on the surfaces of an ellipsoidal particle model. The hydrodynamic stresses and other forces on the surface of the particle are used to determine the cell deformation. We extended previous works, which were based on the Newtonian fluid models, to the non-Newtonian case, and focus on imposed shear rate values between 1 and 100 per second. Two viscosity models are investigated, which respectively correspond to a normal person and a patient with cerebrovascular accident (CVA). The results are compared with those obtained assuming a Newtonian model. We observed that the orientation of the cell influences the deformation and the imposed shear rate drives the local shear rate distribution along the particle surface. The integral particle deformation for the non-Newtonian models in the given shear rate regime is higher than that for the Newtonian reference model. Finally, the deformation of the cell surface decreases as the dissipation ratio increases.
Shear-lag analysis about an internally-dropped ply

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vizzini, A.J.

1995-12-31

The region around a terminated ply is modeled as several elastic layers separated by shear regions. A shear-lag analysis is then performed allowing for the thickness of the elastic and shear layers to vary. Boundary conditions, away for the ply drop, are based on the deflections determined by a finite element model. The interlaminar stresses are compared against those generated by the finite element model for tapered laminates under pure extension, pure bending, and extension-bending coupling. The shear-lag analysis predicts the interlaminar shear at and near the ply drop for pure extension and in cases involving bending if the deflectionsmore » due to bending are removed. The interlaminar shear stress and force equilibrium are used to determine the interlaminar normal stress. The trends in the interlaminar normal stress shown by the finite element model are partially captured by the shear-lag analysis. This simple analysis indicates that the mechanism for load transfer about a ply drop is primarily due to shear transfer through the resin rich areas.« less
[A study on the expression of HSP70 in endothelial cells pretreated with ethanol and fluid shear stress].

PubMed

Yan, Hong-tao; Zhang, Yi; Liao, Ga; Zhang, Kui; Li, Bin; Wang, Ye; Liao, Zhi-gang

2006-07-01

To detect whether ethanol can affect the expression of HSP70 in endothelial cells under fluid shear stress. Ethanol at different concentrations was added to the culture medium of endothelial cells, EA. Hy926, which was treated statically or under 1Pa fluid shear stress. After the incubation of 1 h, 2 h, 4 h and 6 h, the expression of HSP70 was detected by immunohistochemical method(SP). In the control group, the expression of HSP70 was negative under static state, while it was positive under 1Pa fluid shear stress lasting 4 h even without ethanol. No statistic difference was found between the 50 mg/dL ethanol group and the control group with the same treatment time of fluid shear stress. HSP70 expression was found under static state with 150 mg/dL ethanol after 4 h or 300 mg/dL ethanol after 2 h respectively. The expression increased greatly under 1Pa fluid shear stress in the same ethanol concentrations. Medium to high ethanol concentration in coordination with fluid shear stress can strongly stimulates the expression of HSP70 by a kinetic mechanism of time-dependent.
Doppler optical coherence tomography imaging of local fluid flow and shear stress within microporous scaffolds

NASA Astrophysics Data System (ADS)

Jia, Yali; Bagnaninchi, Pierre O.; Yang, Ying; Haj, Alicia El; Hinds, Monica T.; Kirkpatrick, Sean J.; Wang, Ruikang K.

2009-05-01

Establishing a relationship between perfusion rate and fluid shear stress in a 3D cell culture environment is an ongoing and challenging task faced by tissue engineers. We explore Doppler optical coherence tomography (DOCT) as a potential imaging tool for in situ monitoring of local fluid flow profiles inside porous chitosan scaffolds. From the measured fluid flow profiles, the fluid shear stresses are evaluated. We examine the localized fluid flow and shear stress within low- and high-porosity chitosan scaffolds, which are subjected to a constant input flow rate of 0.5 ml.min-1. The DOCT results show that the behavior of the fluid flow and shear stress in micropores is strongly dependent on the micropore interconnectivity, porosity, and size of pores within the scaffold. For low-porosity and high-porosity chitosan scaffolds examined, the measured local fluid flow and shear stress varied from micropore to micropore, with a mean shear stress of 0.49+/-0.3 dyn.cm-2 and 0.38+/-0.2 dyn.cm-2, respectively. In addition, we show that the scaffold's porosity and interconnectivity can be quantified by combining analyses of the 3D structural and flow images obtained from DOCT.
Microfluidic perfusion culture chip providing different strengths of shear stress for analysis of vascular endothelial function.

PubMed

Hattori, Koji; Munehira, Yoichi; Kobayashi, Hideki; Satoh, Taku; Sugiura, Shinji; Kanamori, Toshiyuki

2014-09-01

We developed a microfluidic perfusion cell culture chip that provides three different shear stress strengths and a large cell culture area for the analysis of vascular endothelial functions. The microfluidic network was composed of shallow flow-control channels of three different depths and deep cell culture channels. The flow-control channels with high fluidic resistances created shear stress strengths ranging from 1.0 to 10.0 dyn/cm(2) in the cell culture channels. The large surface area of the culture channels enabled cultivation of a large number (approximately 6.0 × 10(5)) of cells. We cultured human umbilical vein endothelial cells (HUVECs) and evaluated the changes in cellular morphology and gene expression in response to applied shear stress. The HUVECs were aligned in the direction of flow when exposed to a shear stress of 10.0 dyn/cm(2). Compared with conditions of no shear stress, endothelial nitric oxide synthase mRNA expression increased by 50% and thrombomodulin mRNA expression increased by 8-fold under a shear stress of 9.5 dyn/cm(2). Copyright © 2014 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.
The Viscoelastic Effect of Triggered Earthquakes in Various Tectonic Regions On a Global Scale

NASA Astrophysics Data System (ADS)

Sunbul, F.

2015-12-01

The relation between static stress changes and earthquake triggering has important implications for seismic hazard analysis. Considering long time difference between triggered events, viscoelastic stress transfer plays an important role in stress accumulation along the faults. Developing a better understanding of triggering effects may contribute to improvement of quantification of seismic hazard in tectonically active regions. Parsons (2002) computed the difference between the rate of earthquakes occurring in regions where shear stress increased and those regions where the shear stress decreased on a global scale. He found that 61% of the earthquakes occurred in regions with a shear stress increase, while 39% of events occurred in areas of shear stress decrease. Here, we test whether the inclusion of viscoelastic stress transfer affects the results obtained by Parsons (2002) for static stress transfer. Doing such a systematic analysis, we use Global Centroid Moment Tensor (CMT) catalog selecting 289 Ms>7 main shocks with their ~40.500 aftershocks located in ±2° circles for 5 years periods. For the viscoelastic post seismic calculations, we adapt 12 different published rheological models for 5 different tectonic regions. In order to minimise the uncertainties in this CMT catalog, we use the Frohlich and Davis (1999) statistical approach simultaneously. Our results shows that the 5590 aftershocks are triggered by the 289 Ms>7 earthquakes. 3419 of them are associated with calculated shear stress increase, while 2171 are associated with shear stress decrease. The summation of viscoelastic stress shows that, of the 5840 events, 3530 are associated with shear stress increases, and 2312 with shear stress decrease. This result shows an average 4.5% increase in total, the rate of increase in positive and negative areas are 3.2% and 6.5%, respectively. Therefore, over long time periods viscoelastic relaxation represents a considerable contribution to the total stress on neighbouring faults.
Relaxation approximation in the theory of shear turbulence

NASA Technical Reports Server (NTRS)

Rubinstein, Robert

1995-01-01

Leslie's perturbative treatment of the direct interaction approximation for shear turbulence (Modern Developments in the Theory of Turbulence, 1972) is applied to derive a time dependent model for the Reynolds stresses. The stresses are decomposed into tensor components which satisfy coupled linear relaxation equations; the present theory therefore differs from phenomenological Reynolds stress closures in which the time derivatives of the stresses are expressed in terms of the stresses themselves. The theory accounts naturally for the time dependence of the Reynolds normal stress ratios in simple shear flow. The distortion of wavenumber space by the mean shear plays a crucial role in this theory.
Torsional bridge setup for the characterization of integrated circuits and microsensors under mechanical shear stress.

PubMed

Herrmann, M; Gieschke, P; Ruther, P; Paul, O

2011-12-01

We present a torsional bridge setup for the electro-mechanical characterization of devices integrated in the surface of silicon beams under mechanical in-plane shear stress. It is based on the application of a torsional moment to the longitudinal axis of the silicon beams, which results in a homogeneous in-plane shear stress in the beam surface. The safely applicable shear stresses span the range of ±50 MPa. Thanks to a specially designed clamping mechanism, the unintended normal stress typically stays below 2.5% of the applied shear stress. An analytical model is presented to compute the induced shear stress. Numerical computations verify the analytical results and show that the homogeneity of the shear stress is very high on the beam surface in the region of interest. Measurements with piezoresistive microsensors fabricated using a complementary metal-oxide-semiconductor process show an excellent agreement with both the computational results and comparative measurements performed on a four-point bending bridge. The electrical connection to the silicon beam is performed with standard bond wires. This ensures that minimal forces are applied to the beam by the electrical interconnection to the external instrumentation and that devices with arbitrary bond pad layout can be inserted into the setup.
Effects of unidirectional flow shear stresses on the formation, fractal microstructure and rigidity of incipient whole blood clots and fibrin gels.

PubMed

Badiei, N; Sowedan, A M; Curtis, D J; Brown, M R; Lawrence, M J; Campbell, A I; Sabra, A; Evans, P A; Weisel, J W; Chernysh, I N; Nagaswami, C; Williams, P R; Hawkins, K

2015-01-01

Incipient clot formation in whole blood and fibrin gels was studied by the rheometric techniques of controlled stress parallel superposition (CSPS) and small amplitude oscillatory shear (SAOS). The effects of unidirectional shear stress on incipient clot microstructure, formation kinetics and elasticity are reported in terms of the fractal dimension (df) of the fibrin network, the gel network formation time (TGP) and the shear elastic modulus, respectively. The results of this first haemorheological application of CSPS reveal the marked sensitivity of incipient clot microstructure to physiologically relevant levels of shear stress, these being an order of magnitude lower than have previously been studied by SAOS. CSPS tests revealed that exposure of forming clots to increasing levels of shear stress produces a corresponding elevation in df, consistent with the formation of tighter, more compact clot microstructures under unidirectional flow. A corresponding increase in shear elasticity was recorded. The scaling relationship established between shear elasticity and df for fibrin clots and whole blood confirms the fibrin network as the dominant microstructural component of the incipient clot in terms of its response to imposed stress. Supplementary studies of fibrin clot formation by rheometry and microscopy revealed the substantial additional network mass required to increase df and provide evidence to support the hypothesis that microstructural changes in blood clotted under unidirectional shear may be attributed to flow enhanced thrombin generation and activation. CSPS also identified a threshold value of unidirectional shear stress above which no incipient clot formation could be detected. CSPS was shown to be a valuable haemorheological tool for the study of the effects of physiological and pathological levels of shear on clot properties.
Wall shear measurement in sand-water mixture flows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yucel, O.; Grad, W.H.

1975-07-01

The wall shear stress was measured in clear-water and sand-water mixture flows with the use of a flush-mounting hot-film shear-sensor. Data were obtained with 2 shear-sensors and 2 different sands (d50 = 0.45 mm and d50 = 0.88 mm) with solids concentrations of up to Cmax = 1.6% by vol, and for flow Reynolds number of 10/sup 5/ < RD < 6 x 10/sup 5/. The measured sensor wall shear stresses were compared with the true wall shear stresses obtained with the energy head loss measurements conducted in a pipeline system. The results of the tests in the clear-water flowsmore » confirmed the relationship between the sensor power output, Ps, and the wall shear stress, tauo, given by tauo1/3 = APs + B, in which A and B are calibration coefficients. The tests with the low-concentration sand-water mixtures in a vertical pipe indicated that for the present range of experiments, sensor power outputs with the mixtures exceeded those for clear-water by an average of 5%. It is shown that the shear sensors are delicate but accurate instruments that can be used for the measurement of the wall shear stress. (13 refs.)« less
Effect of contact time and force on monocyte adhesion to vascular endothelium.

PubMed Central

Rinker, K D; Prabhakar, V; Truskey, G A

2001-01-01

In this study we examined whether monocytic cell attachment to vascular endothelium was affected by elevating shear stress at a constant shear rate. Contact time, which is inversely related to the shear rate, was fixed and viscosity elevated with dextran to increase the shear stress (and hence the net force on the cell) independently of shear rate. At a fixed contact time, tethering frequencies increased, rolling velocities decreased, and median arrest durations increased with increasing shear stress. Rolling and short arrests (< 0.2 s) were well fit by a single exponential consistent with adhesion via the formation of a single additional bond. The cell dissociation constant, k(off), increased when the shear stress was elevated at constant shear rate. Firmly adherent cells arresting for at least 0.2 s were well fit by a stochastic model involving dissociation from multiple bonds. Therefore, at a fixed contact time and increasing shear stress, bonds formed more frequently for rolling cells resulting in more short arrests, and more bonds formed for firmly arresting cells resulting in longer arrest durations. Possible mechanisms for this increased adhesion include greater monocyte deformation and/or more frequent penetration of microvilli through steric and charge barriers. PMID:11259286

Estimating boundary shear stress along vegetated streambanks with turbulent kinetic energy

NASA Astrophysics Data System (ADS)

Hopkinson, L. C.; Wynn, T.

2010-12-01

Boundary shear stress (BSS) is critical to correctly predict streambank erosion rates and stable channel design and has been estimated using turbulent kinetic energy (TKE). Typically TKE is used in ocean and fluvial environments to determine bed shear stress where the proportionality coefficient (C1) ranges from 0.19 to 0.21. TKE has only recently been used to estimate boundary shear stress along sloping streambanks. This study examined the relationship between boundary shear stress and turbulent kinetic energy along vegetated streambanks for three vegetation treatments: bare, tree, and shrub. A flume study was conducted, modeling a second order prototype stream (Tom’s Creek in Blacksburg, VA) with individual reaches dominated by two vegetation types (trees and shrubs). Boundary shear stress was measured using a flush-mount hot-film anemometer, and three-dimensional velocity was measured using an acoustic Doppler velocimeter 0.5 cm from the boundary. The relationship between TKE and BSS (BSS=C1TKE) was examined by calculating a no-intercept regression model. The calculated C1 ranged from 0.11 to 0.53 for all vegetation types (MRes=0.018-0.086). No-intercept regression models with TKE and the Reynolds stresses (τuv, τuw, and τvw) were also examined as Reynolds stresses have been used to calculate C1. There was better agreement with the reported C1 range for the TKE and Reynolds stress relationship (C1=0.17-0.21 and MRes<0.0072 for the τvw relationship) than with the measured values of shear stress, likely due to the dominance of turbulence generation. While these results are consistent with previously reported values, the relationship should be further explored with measured values of shear stress to determine the trends along hydraulically rough boundaries.
Role of xanthine oxidoreductase and NAD(P)H oxidase in endothelial superoxide production in response to oscillatory shear stress

NASA Technical Reports Server (NTRS)

McNally, J. Scott; Davis, Michael E.; Giddens, Don P.; Saha, Aniket; Hwang, Jinah; Dikalov, Sergey; Jo, Hanjoong; Harrison, David G.

2003-01-01

Oscillatory shear stress occurs at sites of the circulation that are vulnerable to atherosclerosis. Because oxidative stress contributes to atherosclerosis, we sought to determine whether oscillatory shear stress increases endothelial production of reactive oxygen species and to define the enzymes responsible for this phenomenon. Bovine aortic endothelial cells were exposed to static, laminar (15 dyn/cm2), and oscillatory shear stress (+/-15 dyn/cm2). Oscillatory shear increased superoxide (O2.-) production by more than threefold over static and laminar conditions as detected using electron spin resonance (ESR). This increase in O2*- was inhibited by oxypurinol and culture of endothelial cells with tungsten but not by inhibitors of other enzymatic sources. Oxypurinol also prevented H2O2 production in response to oscillatory shear stress as measured by dichlorofluorescin diacetate and Amplex Red fluorescence. Xanthine-dependent O2*- production was increased in homogenates of endothelial cells exposed to oscillatory shear stress. This was associated with decreased xanthine dehydrogenase (XDH) protein levels and enzymatic activity resulting in an elevated ratio of xanthine oxidase (XO) to XDH. We also studied endothelial cells lacking the p47phox subunit of the NAD(P)H oxidase. These cells exhibited dramatically depressed O2*- production and had minimal XO protein and activity. Transfection of these cells with p47phox restored XO protein levels. Finally, in bovine aortic endothelial cells, prolonged inhibition of the NAD(P)H oxidase with apocynin decreased XO protein levels and prevented endothelial cell stimulation of O2*- production in response to oscillatory shear stress. These data suggest that the NAD(P)H oxidase maintains endothelial cell XO levels and that XO is responsible for increased reactive oxygen species production in response to oscillatory shear stress.
In vitro shear stress measurements using particle image velocimetry in a family of carotid artery models: effect of stenosis severity, plaque eccentricity, and ulceration.

PubMed

Kefayati, Sarah; Milner, Jaques S; Holdsworth, David W; Poepping, Tamie L

2014-01-01

Atherosclerotic disease, and the subsequent complications of thrombosis and plaque rupture, has been associated with local shear stress. In the diseased carotid artery, local variations in shear stress are induced by various geometrical features of the stenotic plaque. Greater stenosis severity, plaque eccentricity (symmetry) and plaque ulceration have been associated with increased risk of cerebrovascular events based on clinical trial studies. Using particle image velocimetry, the levels and patterns of shear stress (derived from both laminar and turbulent phases) were studied for a family of eight matched-geometry models incorporating independently varied plaque features - i.e. stenosis severity up to 70%, one of two forms of plaque eccentricity, and the presence of plaque ulceration). The level of laminar (ensemble-averaged) shear stress increased with increasing stenosis severity resulting in 2-16 Pa for free shear stress (FSS) and approximately double (4-36 Pa) for wall shear stress (WSS). Independent of stenosis severity, marked differences were found in the distribution and extent of shear stress between the concentric and eccentric plaque formations. The maximum WSS, found at the apex of the stenosis, decayed significantly steeper along the outer wall of an eccentric model compared to the concentric counterpart, with a 70% eccentric stenosis having 249% steeper decay coinciding with the large outer-wall recirculation zone. The presence of ulceration (in a 50% eccentric plaque) resulted in both elevated FSS and WSS levels that were sustained longer (∼20 ms) through the systolic phase compared to the non-ulcerated counterpart model, among other notable differences. Reynolds (turbulent) shear stress, elevated around the point of distal jet detachment, became prominent during the systolic deceleration phase and was widely distributed over the large recirculation zone in the eccentric stenoses.
In-shoe plantar tri-axial stress profiles during maximum-effort cutting maneuvers.

PubMed

Cong, Yan; Lam, Wing Kai; Cheung, Jason Tak-Man; Zhang, Ming

2014-12-18

Soft tissue injuries, such as anterior cruciate ligament rupture, ankle sprain and foot skin problems, frequently occur during cutting maneuvers. These injuries are often regarded as associated with abnormal joint torque and interfacial friction caused by excessive external and in-shoe shear forces. This study simultaneously investigated the dynamic in-shoe localized plantar pressure and shear stress during lateral shuffling and 45° sidestep cutting maneuvers. Tri-axial force transducers were affixed at the first and second metatarsal heads, lateral forefoot, and heel regions in the midsole of a basketball shoe. Seventeen basketball players executed both cutting maneuvers with maximum efforts. Lateral shuffling cutting had a larger mediolateral braking force than 45° sidestep cutting. This large braking force was concentrated at the first metatarsal head, as indicated by its maximum medial shear stress (312.2 ± 157.0 kPa). During propulsion phase, peak shear stress occurred at the second metatarsal head (271.3 ± 124.3 kPa). Compared with lateral shuffling cutting, 45° sidestep cutting produced larger peak propulsion shear stress (463.0 ± 272.6 kPa) but smaller peak braking shear stress (184.8 ± 181.7 kPa), of which both were found at the first metatarsal head. During both cutting maneuvers, maximum medial and posterior shear stress occurred at the first metatarsal head, whereas maximum pressure occurred at the second metatarsal head. The first and second metatarsal heads sustained relatively high pressure and shear stress and were expected to be susceptible to plantar tissue discomfort or injury. Due to different stress distribution, distinct pressure and shear cushioning mechanisms in basketball footwear might be considered over different foot regions. Copyright © 2014 Elsevier Ltd. All rights reserved.
Effects of Fluid Shear Stress on Cancer Stem Cell Viability

NASA Astrophysics Data System (ADS)

Sunday, Brittney; Triantafillu, Ursula; Domier, Ria; Kim, Yonghyun

2014-11-01

Cancer stem cells (CSCs), which are believed to be the source of tumor formation, are exposed to fluid shear stress as a result of blood flow within the blood vessels. It was theorized that CSCs would be less susceptible to cell death than non-CSCs after both types of cell were exposed to a fluid shear stress, and that higher levels of fluid shear stress would result in lower levels of cell viability for both cell types. To test this hypothesis, U87 glioblastoma cells were cultured adherently (containing smaller populations of CSCs) and spherically (containing larger populations of CSCs). They were exposed to fluid shear stress in a simulated blood flow through a 125-micrometer diameter polyetheretherketone (PEEK) tubing using a syringe pump. After exposure, cell viability data was collected using a BioRad TC20 Automated Cell Counter. Each cell type was tested at three physiological shear stress values: 5, 20, and 60 dynes per centimeter squared. In general, it was found that the CSC-enriched U87 sphere cells had higher cell viability than the CSC-depleted U87 adherent cancer cells. Interestingly, it was also observed that the cell viability was not negatively affected by the higher fluid shear stress values in the tested range. In future follow-up studies, higher shear stresses will be tested. Furthermore, CSCs from different tumor origins (e.g. breast tumor, prostate tumor) will be tested to determine cell-specific shear sensitivity. National Science Foundation Grant #1358991 supported the first author as an REU student.
A systematic analysis of eight decades of incipient motion studies, with special reference to gravel-bedded rivers

Treesearch

John M. Buffington; David R. Montgomery

1997-01-01

Data compiled from eight decades of incipient motion studies were used to calculate dimensionless critical shear stress values of the median grain size, T*c50. Calculated T*c50 values were stratified by initial motion definition, median grain size type (surface, subsurface, or laboratory mixture), relative roughness, and flow regime. A traditional Shields plot...
Shear-stress sensitive lenticular vesicles for targeted drug delivery.

PubMed

Holme, Margaret N; Fedotenko, Illya A; Abegg, Daniel; Althaus, Jasmin; Babel, Lucille; Favarger, France; Reiter, Renate; Tanasescu, Radu; Zaffalon, Pierre-Léonard; Ziegler, André; Müller, Bert; Saxer, Till; Zumbuehl, Andreas

2012-08-01

Atherosclerosis results in the narrowing of arterial blood vessels and this causes significant changes in the endogenous shear stress between healthy and constricted arteries. Nanocontainers that can release drugs locally with such rheological changes can be very useful. Here, we show that vesicles made from an artificial 1,3-diaminophospholipid are stable under static conditions but release their contents at elevated shear stress. These vesicles have a lenticular morphology, which potentially leads to instabilities along their equator. Using a model cardiovascular system based on polymer tubes and an external pump to represent shear stress in healthy and constricted vessels of the heart, we show that drugs preferentially release from the vesicles in constricted vessels that have high shear stress.
Shear-stress sensitive lenticular vesicles for targeted drug delivery

NASA Astrophysics Data System (ADS)

Holme, Margaret N.; Fedotenko, Illya A.; Abegg, Daniel; Althaus, Jasmin; Babel, Lucille; Favarger, France; Reiter, Renate; Tanasescu, Radu; Zaffalon, Pierre-Léonard; Ziegler, André; Müller, Bert; Saxer, Till; Zumbuehl, Andreas

2012-08-01

Atherosclerosis results in the narrowing of arterial blood vessels and this causes significant changes in the endogenous shear stress between healthy and constricted arteries. Nanocontainers that can release drugs locally with such rheological changes can be very useful. Here, we show that vesicles made from an artificial 1,3-diaminophospholipid are stable under static conditions but release their contents at elevated shear stress. These vesicles have a lenticular morphology, which potentially leads to instabilities along their equator. Using a model cardiovascular system based on polymer tubes and an external pump to represent shear stress in healthy and constricted vessels of the heart, we show that drugs preferentially release from the vesicles in constricted vessels that have high shear stress.
Frictional response of simulated faults to normal stresses perturbations probed with ultrasonic waves

NASA Astrophysics Data System (ADS)

Shreedharan, S.; Riviere, J.; Marone, C.

2017-12-01

We report on a suite of laboratory friction experiments conducted on saw-cut Westerly Granite surfaces to probe frictional response to step changes in normal stress and loading rate. The experiments are conducted to illuminate the fundamental processes that yield friction rate and state dependence. We quantify the microphysical frictional response of the simulated fault surfaces to normal stress steps, in the range of 1% - 600% step increases and decreases from a nominal baseline normal stress. We measure directly the fault slip rate and account for changes in slip rate with changes in normal stress and complement mechanical data acquisition by continuously probing the faults with ultrasonic pulses. We conduct the experiments at room temperature and humidity conditions in a servo controlled biaxial testing apparatus in the double direct shear configuration. The samples are sheared over a range of velocities, from 0.02 - 100 μm/s. We report observations of a transient shear stress and friction evolution with step increases and decreases in normal stress. Specifically, we show that, at low shear velocities and small increases in normal stress (<5% increase), the shear stress on the fault does not increase instantaneously with the normal stress step while the ultrasonic wave amplitude and normal displacement do. In other words, the shear stress does not follow the load point stiffness curve. At high shear velocities and larger normal stress steps (> 5% increases), the shear stress evolves immediately with normal stress. We show that the excursions in slip rate resulting from the changes in normal stress must be accounted for in order to predict fault strength evolution. Ultrasonic wave amplitudes which first increase immediately in response to normal stress steps, then decrease approximately linearly to a new steady state value, in part due to changes in fault slip rate. Previous descriptions of frictional state evolution during normal stress perturbations have not adequately accounted for the effect of large slip velocity excursions. Here, we attempt to do so by using the measured ultrasonic amplitudes as a proxy for frictional state during transient shear stress evolution. Our work aims to improve understanding of induced and triggered seismicity with focus on simulating static triggering using rate and state friction.
Actuated rheology of magnetic micro-swimmers suspensions: Emergence of motor and brake states

NASA Astrophysics Data System (ADS)

Vincenti, Benoit; Douarche, Carine; Clement, Eric

2018-03-01

We study the effect of magnetic field on the rheology of magnetic micro-swimmers suspensions. We use a model of a dilute suspension under simple shear and subjected to a constant magnetic field. Particle shear stress is obtained for both pusher and puller types of micro-swimmers. In the limit of low shear rate, the rheology exhibits a constant shear stress, called actuated stress, which only depends on the swimming activity of the particles. This stress is induced by the magnetic field and can be positive (brake state) or negative (motor state). In the limit of low magnetic fields, a scaling relation of the motor-brake effect is derived as a function of the dimensionless parameters of the model. In this case, the shear stress is an affine function of the shear rate. The possibilities offered by such an active system to control the rheological response of a fluid are finally discussed.
Characterization of Fillite as a planetary soil simulant in support of rover mobility assessment in high-sinkage/high-slip environments

NASA Astrophysics Data System (ADS)

Edwards, Michael

This thesis presents the results of a research program characterizing a soil simulant called Fillite, which is composed of alumino-silicate hollow microspheres harvested from the pulverized fuel ash of coal-fired power plants. Fillite is available in large quantities at a reasonable cost and it is chemically inert. Fillite has been selected by the National Aeronautics and Space Administration (NASA) Glenn Research Center to simulate high-sinkage/high-slip environment in a large test bed such as the ones encountered by the Spirit rover on Mars in 2009 when it became entrapped in a pocket of soft, loose regolith on Mars. The terms high-sinkage and high-slip used here describe the interaction of soils with typical rover wheels. High-sinkage refers to a wheel sinking with little to no applied force while high-slip refers to a spinning wheel with minimal traction. Standard material properties (density, specific gravity, compression index, Young's modulus, and Poisson's ratio) of Fillite were determined from a series of laboratory tests conducted in general accordance with ASTM standards. Tests were also performed to determine some less standard material properties of Fillite such as the small strain shear wave velocity, maximum shear modulus, and several pressure-sinkage parameters for use in pressure-sinkage models. The experiments include an extensive series of triaxial compression tests, bender element tests, and normal and shear bevameter tests. The unit weight of Fillite on Earth ranges between 3.9 and 4.8 kN/m 3, which is similar to that of Martian regolith (about 3.7 -- 5.6 kN/m3) on Mars and close to the range of the unit weight of lunar regolith (about 1.4 -- 2.9 kN/m3) on the Moon. The data presented here support that Fillite has many physical and mechanical properties that are similar to what is known about Martian regolith. These properties are also comparable to lunar regolith. Fillite is quite dilatant; its peak and critical angles of internal friction are smaller than those of most other simulants. Smaller shear strength, coupled with much smaller bulk unit weight as compared to other simulants, results in smaller bearing and shearing resistances allowing for better simulation of the intended high-sinkage, high-slip behavior for rover mobility studies. The results of the normal bevameter tests were used to determine parameters for two models available in the literature - the Bekker model and the New Model of Mobility (N2M) model. These parameters were then used to predict the sinkage of a Spirit rover wheel if the rover were to be used on Fillite. The predicted sinkage of a Spirit rover wheel in Fillite was 84% of the wheel diameter, which was within the observed sinkage of 50 to 90% of the wheel diameter of the Spirit rover on Mars. Shear bevameter tests were also performed on Fillite to assess the shear stresses and shear deformations imparted by wheels under torsional loads. The results compared well to the estimated shear stresses and deformations of Martian soil caused by the wheels of the Spirit rover. When compared to other simulants (e.g. GRC-1), the pressure-sinkage and shear stress-shear deformation behaviors of Fillite confirm that Fillite is more suitable for high-sinkage and high-slip rover studies than other typical simulants derived from natural terrestrial soils and rocks.
Effect of clazosentan, a selective endothelin A receptor antagonist, and tezosentan, a dual endothelin A/B antagonist, on pulsatile shear stress induced constriction of the iliac in the anaesthetized pig.

PubMed

Ruane-O'Hora, Therese; Rae, Mark George; Markos, Farouk

2011-08-01

1. The effects of changes in mean and pulsatile shear stress on the diameter of the iliac of the anaesthetized pig were investigated in the presence of clazosentan and tezosentan. 2. A total of 17 pigs were used. Mean shear stress was increased by infusing acetylcholine downstream (2-20 μg/min) through the deep femoral artery. Pulsatile shear stress was enhanced first by injecting varying volumes (1-10 mL) of calcium gluconate (stock 10 mg/mL) directly into the left ventricle. Second, by electrical stimulation of the left sympathetic nerves to the heart (1-16 Hz, 4 min duration, supramaximal voltage). 3. An increase in mean shear stress induced a vasodilation that was not altered significantly by the selective endothelin A antagonist clazosentan (10 mg/kg i.v.). Similarly, the vasoconstriction induced by an increase in pulsatile shear stress brought about by either calcium gluconate injections or left sympathetic nerve stimulation was unaffected by clazosentan. However, tezosentan (10 mg/kg i.v.), significantly attenuated the vasoconstriction induced by an increase in pulsatile shear stress. 4. In conclusion, an increase in pulsatile shear stress causes vasoconstriction of the pig iliac artery, which is attenuated by dual endothelin receptor antagonism, but not by specific endothelin A blockade. © 2011 The Authors. Clinical and Experimental Pharmacology and Physiology © 2011 Blackwell Publishing Asia Pty Ltd.
Quantification of wall shear stress in large blood vessels using Lagrangian interpolation functions with cine phase-contrast magnetic resonance imaging.

PubMed

Cheng, Christopher P; Parker, David; Taylor, Charles A

2002-09-01

Arterial wall shear stress is hypothesized to be an important factor in the localization of atherosclerosis. Current methods to compute wall shear stress from magnetic resonance imaging (MRI) data do not account for flow profiles characteristic of pulsatile flow in noncircular vessel lumens. We describe a method to quantify wall shear stress in large blood vessels by differentiating velocity interpolation functions defined using cine phase-contrast MRI data on a band of elements in the neighborhood of the vessel wall. Validation was performed with software phantoms and an in vitro flow phantom. At an image resolution corresponding to in vivo imaging data of the human abdominal aorta, time-averaged, spatially averaged wall shear stress for steady and pulsatile flow were determined to be within 16% and 23% of the analytic solution, respectively. These errors were reduced to 5% and 8% with doubling in image resolution. For the pulsatile software phantom, the oscillation in shear stress was predicted to within 5%. The mean absolute error of circumferentially resolved shear stress for the nonaxisymmetric phantom decreased from 28% to 15% with a doubling in image resolution. The irregularly shaped phantom and in vitro investigation demonstrated convergence of the calculated values with increased image resolution. We quantified the shear stress at the supraceliac and infrarenal regions of a human abdominal aorta to be 3.4 and 2.3 dyn/cm2, respectively.
Stress transfer mechanisms at the submicron level for graphene/polymer systems.

PubMed

Anagnostopoulos, George; Androulidakis, Charalampos; Koukaras, Emmanuel N; Tsoukleri, Georgia; Polyzos, Ioannis; Parthenios, John; Papagelis, Konstantinos; Galiotis, Costas

2015-02-25

The stress transfer mechanism from a polymer substrate to a nanoinclusion, such as a graphene flake, is of extreme interest for the production of effective nanocomposites. Previous work conducted mainly at the micron scale has shown that the intrinsic mechanism of stress transfer is shear at the interface. However, since the interfacial shear takes its maximum value at the very edge of the nanoinclusion it is of extreme interest to assess the effect of edge integrity upon axial stress transfer at the submicron scale. Here, we conduct a detailed Raman line mapping near the edges of a monolayer graphene flake that is simply supported onto an epoxy-based photoresist (SU8)/poly(methyl methacrylate) matrix at steps as small as 100 nm. We show for the first time that the distribution of axial strain (stress) along the flake deviates somewhat from the classical shear-lag prediction for a region of ∼ 2 μm from the edge. This behavior is mainly attributed to the presence of residual stresses, unintentional doping, and/or edge effects (deviation from the equilibrium values of bond lengths and angles, as well as different edge chiralities). By considering a simple balance of shear-to-normal stresses at the interface we are able to directly convert the strain (stress) gradient to values of interfacial shear stress for all the applied tensile levels without assuming classical shear-lag behavior. For large flakes a maximum value of interfacial shear stress of 0.4 MPa is obtained prior to flake slipping.
Evolution of permeability and Biot coefficient at high mean stresses in high porosity sandstone

DOE PAGES

Ingraham, Mathew D.; Bauer, Stephen J.; Issen, Kathleen A.; ...

2017-05-01

A series of constant mean stress (CMS) and constant shear stress (CSS) tests were performed to investigate the evolution of permeability and Biot coefficient at high mean stresses in a high porosity reservoir analog (Castlegate sandstone). Permeability decreases as expected with increasing mean stress, from about 20 Darcy at the beginning of the tests to between 1.5 and 0.3 Darcy at the end of the tests (mean stresses up to 275 MPa). The application of shear stress causes permeability to drop below that of a hydrostatic test at the same mean stress. Results show a nearly constant rate decrease inmore » the Biot coefficient as the mean stress increases during hydrostatic loading, and as the shear stress increases during CMS loading. In conclusion, CSS tests show a stabilization of the Biot coefficient after the application of shear stress.« less
Evolution of permeability and Biot coefficient at high mean stresses in high porosity sandstone

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ingraham, Mathew D.; Bauer, Stephen J.; Issen, Kathleen A.

A series of constant mean stress (CMS) and constant shear stress (CSS) tests were performed to investigate the evolution of permeability and Biot coefficient at high mean stresses in a high porosity reservoir analog (Castlegate sandstone). Permeability decreases as expected with increasing mean stress, from about 20 Darcy at the beginning of the tests to between 1.5 and 0.3 Darcy at the end of the tests (mean stresses up to 275 MPa). The application of shear stress causes permeability to drop below that of a hydrostatic test at the same mean stress. Results show a nearly constant rate decrease inmore » the Biot coefficient as the mean stress increases during hydrostatic loading, and as the shear stress increases during CMS loading. In conclusion, CSS tests show a stabilization of the Biot coefficient after the application of shear stress.« less
Effects of hydrodynamic conditions on the sorption behaviors of aniline on sediment with coexistence of nitrobenzene.

PubMed

Wang, Peng; Hua, Zulin; Cai, Yunjie; Shen, Xia; Li, Qiongqiong; Liu, Xiaoyuan

2015-08-01

The sorption behaviors of pollutants affected by hydrodynamic conditions were confirmed in natural water environment. The effects of hydrodynamic conditions on the sorption behaviors of aniline on sediment with coexistence of nitrobenzene were investigated. The particle entrainment simulator (PES) was used to simulate varied bottom shear stresses. The batch equilibrium method was applied to the experiments with the stress levels and the action time controlled at 0.2-0.5 N/m(2) and 24 h, respectively. The findings indicated that apparent partition coefficient of aniline on sediment increased with the shear stress significantly, while decreased with nitrobenzene concentration. On the contrary, both the sorption amount of aniline on suspended particulate matter (Q s) and the effect of nitrobenzene concentration on Q s declined as the shear stress increased. The sorption kinetic results showed that the sorption process followed the pseudo-second-order kinetics equation, and the process included two stages: fast sorption stage and slow sorption stage, among which the average sorption rate of fast stage was 7.5-9.5 times that of slow one. The effect of shear stress on the average sorption rate of aniline was enhanced with the increase of nitrobenzene concentration. And shear stress weakened the disturbance of cosolute on main solute sorption process. In addition, experiment results of sorption kinetic show that only the initial sorption rate was affected by shear stress and cosolute concentration. In the first 5 min, shear stress had positive effects on the sorption rate. After that, the sorption rate barely changed with shear stress and cosolute concentration.
Study on shear properties of coral sand under cyclic simple shear condition

NASA Astrophysics Data System (ADS)

Ji, Wendong; Zhang, Yuting; Jin, Yafei

2018-05-01

In recent years, the ocean development in our country urgently needs to be accelerated. The construction of artificial coral reefs has become an important development direction. In this paper, experimental studies of simple shear and cyclic simple shear of coral sand are carried out, and the shear properties and particle breakage of coral sand are analyzed. The results show that the coral sand samples show an overall shear failure in the simple shear test, which is more accurate and effective for studying the particle breakage. The shear displacement corresponding to the peak shear stress of the simple shear test is significantly larger than that corresponding to the peak shear stress of the direct shear test. The degree of particle breakage caused by the simple shear test is significantly related to the normal stress level. The particle breakage of coral sand after the cyclic simple shear test obviously increases compared with that of the simple shear test, and universal particle breakage occurs within the whole particle size range. The increasing of the cycle-index under cyclic simple shear test results in continuous compacting of the sample, so that the envelope curve of peak shearing force increases with the accumulated shear displacement.
An Automatic Braking System That Stabilizes Leukocyte Rolling by an Increase in Selectin Bond Number with Shear

PubMed Central

Chen, Shuqi; Springer, Timothy A.

1999-01-01

Wall shear stress in postcapillary venules varies widely within and between tissues and in response to inflammation and exercise. However, the speed at which leukocytes roll in vivo has been shown to be almost constant within a wide range of wall shear stress, i.e., force on the cell. Similarly, rolling velocities on purified selectins and their ligands in vitro tend to plateau. This may be important to enable rolling leukocytes to be exposed uniformly to activating stimuli on endothelium, independent of local hemodynamic conditions. Wall shear stress increases the rate of dissociation of individual selectin–ligand tether bonds exponentially (1, 4) thereby destabilizing rolling. We find that this is compensated by a shear-dependent increase in the number of bonds per rolling step. We also find an increase in the number of microvillous tethers to the substrate. This explains (a) the lack of firm adhesion through selectins at low shear stress or high ligand density, and (b) the stability of rolling on selectins to wide variation in wall shear stress and ligand density, in contrast to rolling on antibodies (14). Furthermore, our data successfully predict the threshold wall shear stress below which rolling does not occur. This is a special case of the more general regulation by shear of the number of bonds, in which the number of bonds falls below one. PMID:9885254
An automatic braking system that stabilizes leukocyte rolling by an increase in selectin bond number with shear.

PubMed

Chen, S; Springer, T A

1999-01-11

Wall shear stress in postcapillary venules varies widely within and between tissues and in response to inflammation and exercise. However, the speed at which leukocytes roll in vivo has been shown to be almost constant within a wide range of wall shear stress, i.e., force on the cell. Similarly, rolling velocities on purified selectins and their ligands in vitro tend to plateau. This may be important to enable rolling leukocytes to be exposed uniformly to activating stimuli on endothelium, independent of local hemodynamic conditions. Wall shear stress increases the rate of dissociation of individual selectin-ligand tether bonds exponentially (, ) thereby destabilizing rolling. We find that this is compensated by a shear-dependent increase in the number of bonds per rolling step. We also find an increase in the number of microvillous tethers to the substrate. This explains (a) the lack of firm adhesion through selectins at low shear stress or high ligand density, and (b) the stability of rolling on selectins to wide variation in wall shear stress and ligand density, in contrast to rolling on antibodies (). Furthermore, our data successfully predict the threshold wall shear stress below which rolling does not occur. This is a special case of the more general regulation by shear of the number of bonds, in which the number of bonds falls below one.

An improved shear beam method for the characterization of bonded composite joints

NASA Technical Reports Server (NTRS)

Hiel, Clem C.; Brinson, Hal F.

1989-01-01

Closed-form analytical solutions, which govern the displacements and stresses in an adhesive shear beam, are discussed. The remarkable precision with which the shear stresses in the adhesive can be predicted forms the basis of the proposed characterization procedure. The shear modulus of the adhesive is obtained by means of a parameter estimation procedure which requires a symbiosis of theoretical and experimental stress analysis.
Blanking Method with Aid of Scrap to Reduce Tensile Residual Stress on Sheared Edge

NASA Astrophysics Data System (ADS)

Yasutomi, T.; Yonemura, S.; Yoshida, T.; Mizumura, M.; Hiwatashi, S.

2017-09-01

A simple shearing method to reduce tensile residual stress on a sheared edge is highly desired in the automotive industry because this type of stress deteriorates the fatigue property of automotive parts. In this study, the effect of a coining method with a shearing scrap material on a sheared edge was investigated. The scrap part of a sheared plate has a fracture surface shape similar to that of the product part since these parts are generated by separation of a single plate with crack propagation. Therefore, it is possible to impose plastic strain over the entire fracture surface by using the scrap part as a coining tool. Effectiveness of this method was investigated for high-tensile-strength steel. Using this method, the tensile residual stress on the sheared surface was significantly reduced and work hardening was slightly increased. The effects of shearing clearance and coining stroke were also investigated. Tensile residual stress decreased as the coining stroke increased; however, it saturated at a certain stroke. The stroke at which tensile residual stress saturated was relatively small at a large clearance. In particular, the amount of plastic deformation on fracture surface increased when coining stroke became large. These tendencies could be explained by the conditions of contact, which were investigated using finite element analysis.
Laser reflection method for determination of shear stress in low density transitional flows

NASA Astrophysics Data System (ADS)

Sathian, Sarith P.; Kurian, Job

2006-03-01

The details of laser reflection method (LRM) for the determination of shear stress in low density transitional flows are presented. The method is employed to determine the shear stress due to impingement of a low density supersonic free jet issuing out from a convergent divergent nozzle on a flat plate. The plate is smeared with a thin oil film and kept parallel to the nozzle axis. For a thin oil film moving under the action of aerodynamic boundary layer, the shear stress at the air-oil interface is equal to the shear stress between the surface and air. A direct and dynamic measurement of the oil film slope generated by the shear force is done using a position sensing detector (PSD). The thinning rate of the oil film is directly measured which is the major advantage of the LRM. From the oil film slope history, calculation of the shear stress is done using a three-point formula. The range of Knudsen numbers investigated is from 0.028 to 0.516. Pressure ratio across the nozzle varied from 3,500 to 8,500 giving highly under expanded free jets. The measured values of shear, in the overlapping region of experimental parameters, show fair agreement with those obtained by force balance method and laser interferometric method.
Wrinkling of Stretched Films: Shear Stress

NASA Technical Reports Server (NTRS)

Zak, M. A.

1982-01-01

Report presents theoretical investigation on nonlinear shearing characteristics of wrinkling films under applied shear stress. Report helps explain force/deflection characteristic of in-planeboom and solar-array blanket structural combinations.
Simulation of shear thickening in attractive colloidal suspensions.

PubMed

Pednekar, Sidhant; Chun, Jaehun; Morris, Jeffrey F

2017-03-01

The influence of attractive forces between particles under conditions of large particle volume fraction, ϕ, is addressed using numerical simulations which account for hydrodynamic, Brownian, conservative and frictional contact forces. The focus is on conditions for which a significant increase in the apparent viscosity at small shear rates, and possibly the development of a yield stress, is observed. The high shear rate behavior for Brownian suspensions has been shown in recent work [R. Mari, R. Seto, J. F. Morris and M. M. Denn PNAS, 2015, 112, 15326-15330] to be captured by the inclusion of pairwise forces of two forms, one a contact frictional interaction and the second a repulsive force often found in stabilized colloidal dispersions. Under such conditions, shear thickening is observed when shear stress is comparable to the sum of the Brownian stress, kT/a 3 , and a characteristic stress based on the combination of interparticle force, i.e. σ ∼ F 0 /a 2 with kT the thermal energy, F 0 the repulsive force scale and a the particle radius. At sufficiently large ϕ, this shear thickening can be very abrupt. Here it is shown that when attractive interactions are present with the noted forces, the shear thickening is obscured, as the viscosity shear thins with increasing shear rate, eventually descending from an infinite value (yield stress conditions) to a plateau at large stress; this plateau is at the same level as the large-shear rate viscosity found in the shear thickened state without attractive forces. It is shown that this behavior is consistent with prior observations in shear thickening suspensions modified to be attractive through depletion flocculation [V. Gopalakrishnan and C. F. Zukoski J. Rheol., 2004, 48, 1321-1344]. The contributions of the contact, attractive, and hydrodynamics forces to the bulk stress are presented, as are the contact networks found at different attractive strengths.
High-speed high-stress ring shear tests on granular sods and clayey soils

Treesearch

Hiroshi Fukuoka; Kyoji Sassa

1991-01-01

The purposes of this study is to obtain exact knowledge of the influences on friction angle during shear by shearing speeds. Ring shear tests on sandy and clayey materials have been carried out with a newly developed High-speed High-Stress Ring Shear Apparatus to examine if there are some changes in the frictional behaviors of these materials at high shearing speeds of...
Production of functional proteins: balance of shear stress and gravity

NASA Technical Reports Server (NTRS)

Kaysen, James Howard (Inventor); Hammond, Timothy Grant (Inventor); Goodwin, Thomas John (Inventor)

2011-01-01

A method for the production of functional proteins including hormones by renal cells in a three dimensional culturing process responsive to shear stress uses a rotating wall vessel. Natural mixture of renal cells expresses the enzyme 1-.alpha.-hydroxylase which can be used to generate the active form of vitamin D: 1,25-diOH vitamin D.sub.3. The fibroblast cultures and co-culture of renal cortical cells express the gene for erythropoietin and secrete erythropoietin into the culture supernatant. Other shear stress response genes are also modulated by shear stress, such as toxin receptors megalin and cubulin (gp280). Also provided is a method of treating an in-need individual with the functional proteins produced in a three dimensional co-culture process responsive to shear stress using a rotating wall vessel.
Combined effects of physiologically relevant disturbed wall shear stress and glycated albumin on endothelial cell functions associated with inflammation, thrombosis and cytoskeletal dynamics.

PubMed

Maria, Zahra; Yin, Wei; Rubenstein, David Alan

2014-07-01

Diabetes mellitus is a major risk factor in the development of cardiovascular diseases (CVDs). The presence of advanced glycation end-products (AGEs) promotes CVDs by upregulating endothelial cell (EC) inflammatory and thrombotic responses, in a similar manner as disturbed shear stress. However, the combined effect of disturbed shear stress and AGEs on EC function has yet to be determined. Our goal was to evaluate these effects on EC responses. ECs were incubated with AGEs for 5 days. ECs were then subjected to physiological or pathological shear stress. Cell metabolic activity, surface expression of intercellular adhesion molecule-1, thrombomodulin, connexin-43 and caveolin-1, and cytoskeleton organization were quantified. The results show that irreversibly glycated albumin and pathological shear stress increased EC metabolic activity, and upregulated and downregulated the EC surface expression of intercellular adhesion molecule-1 and thrombomodulin, respectively. Expression of connexin-43, caveolin-1 and cytoskeletal organization was independent of shear stress; however, the presence of irreversibly glycated AGEs markedly increased connexin-43, and decreased caveolin-1 expression and actin cytoskeletal connectivity. Our data suggest that irreversibly glycated albumin and disturbed shear stress could promote CVD pathogenesis by enhancing EC inflammatory and thrombotic responses, and through the deterioration of the cytoskeletal organization.
Spatio-temporal characteristics of large scale motions in a turbulent boundary layer from direct wall shear stress measurement

NASA Astrophysics Data System (ADS)

Pabon, Rommel; Barnard, Casey; Ukeiley, Lawrence; Sheplak, Mark

2016-11-01

Particle image velocimetry (PIV) and fluctuating wall shear stress experiments were performed on a flat plate turbulent boundary layer (TBL) under zero pressure gradient conditions. The fluctuating wall shear stress was measured using a microelectromechanical 1mm × 1mm floating element capacitive shear stress sensor (CSSS) developed at the University of Florida. The experiments elucidated the imprint of the organized motions in a TBL on the wall shear stress through its direct measurement. Spatial autocorrelation of the streamwise velocity from the PIV snapshots revealed large scale motions that scale on the order of boundary layer thickness. However, the captured inclination angle was lower than that determined using the classic method by means of wall shear stress and hot-wire anemometry (HWA) temporal cross-correlations and a frozen field hypothesis using a convection velocity. The current study suggests the large size of these motions begins to degrade the applicability of the frozen field hypothesis for the time resolved HWA experiments. The simultaneous PIV and CSSS measurements are also used for spatial reconstruction of the velocity field during conditionally sampled intense wall shear stress events. This material is based upon work supported by the National Science Foundation Graduate Research Fellowship under Grant No. DGE-1315138.
ESTIMATION OF SHEAR STRESS WORKING ON SUBMERGED HOLLOW FIBRE MEMBRANE BY CFD METHOD IN MBRs

NASA Astrophysics Data System (ADS)

Zaw, Hlwan Moe; Li, Tairi; Nagaoka, Hiroshi

This study was conducted to evaluate shear stress working on submerged hollow fibre membrane by CFD (Computation Fluid Dynamics) method in MBRs. Shear stress on hollow fibre membrane caused by aeration was measured directly using a two-direction load sensor. The measurement of water-phase flow velocity was done also by using laser doppler velocimeter. It was confirmed that the shear stress was possible to be evaluated from the water-phase flow velocityby the result of comparison of time average shear stress actually measured with one hollow fibre membrane and the one calculated by the water-phase flow velocity. In the estimation of the water-phase flow velocity using the CFD method, time average water-phase flow velocity estimated by consideration of the fluid resistance of the membrane module nearly coincided with the measured values, and it was shown that it was possible to be estimated also within the membrane module. Moreover, the measured shear stress and drag force well coincided with the values calculated from the estimated water-phase flow velocity outside of membrane module and in the center of membrane module, and it was suggested that the shear stress on the hollow fibre membrane could be estimated by the CFD method in MBRs.
Effect of cell size and shear stress on bacterium growth rate

NASA Astrophysics Data System (ADS)

Fadlallah, Hadi; Jarrahi, Mojtaba; Herbert, Éric; Peerhossaini, Hassan; PEF Team

2015-11-01

Effect of shear stress on the growth rate of Synechocystis and Chlamydomonas cells is studied. An experimental setup was prepared to monitor the growth rate of the microorganisms versus the shear rate inside a clean room, under atmospheric pressure and 20 °C temperature. Digital magnetic agitators are placed inside a closed chamber provided with airflow, under a continuous uniform light intensity over 4 weeks. In order to study the effect of shear stress on the growth rate, different frequencies of agitation are tested, 2 vessels filled with 150 ml of each specie were placed on different agitating system at the desired frequency. The growth rate is monitored daily by measuring the optical density and then correlate it to the cellular concentration. The PH was adjusted to 7 in order to maintain the photosynthetic activity. Furthermore, to measure the shear stress distribution, the flow velocity field was measured using PIV. Zones of high and low shear stress were identified. Results show that the growth rate is independent of the shear stress magnitude, mostly for Synechocystis, and with lower independency for Chlamydomonas depending on the cell size for each species.
Direct Numerical Simulation of Surfactant-Stabilized Emulsions Morphology and Shear Viscosity in Starting Shear Flow

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roar Skartlien; Espen Sollum; Andreas Akselsen

2012-07-01

A 3D lattice Boltzmann model for two-phase flow with amphiphilic surfactant was used to investigate the evolution of emulsion morphology and shear stress in starting shear flow. The interfacial contributions were analyzed for low and high volume fractions and varying surfactant activity. A transient viscoelastic contribution to the emulsion rheology under constant strain rate conditions was attributed to the interfacial stress. For droplet volume fractions below 0.3 and an average capillary number of about 0.25, highly elliptical droplets formed. Consistent with affine deformation models, gradual elongation of the droplets increased the shear stress at early times and reduced it atmore » later times. Lower interfacial tension with increased surfactant activity counterbalanced the effect of increased interfacial area, and the net shear stress did not change significantly. For higher volume fractions, co-continuous phases with a complex topology were formed. The surfactant decreased the interfacial shear stress due mainly to advection of surfactant to higher curvature areas. Our results are in qualitative agreement with experimental data for polymer blends in terms of transient interfacial stresses and limited enhancement of the emulsion viscosity at larger volume fractions where the phases are co-continuous.« less
Experimental study and FEM simulation of the simple shear test of cylindrical rods

NASA Astrophysics Data System (ADS)

Wirti, Pedro H. B.; Costa, André L. M.; Misiolek, Wojciech Z.; Valberg, Henry S.

2018-05-01

In the presented work an experimental simple shear device for cutting cylindrical rods was used to obtain force-displacement data for a low-carbon steel. In addition, and FEM 3D-simulation was applied to obtain internal shear stress and strain maps for this material. The experimental longitudinal grid patterns and force-displacement curve were compared with numerical simulation results. Many aspects of the elastic and plastic deformations were described. It was found that bending reduces the shear yield stress of the rod material. Shearing starts on top and bottom die-workpiece contact lines evolving in an arc-shaped area. Due to this geometry, stress concentrates on the surface of the rod until the level of damage reaches the critical value and the fracture starts here. The volume of material in the plastic zone subjected to shearing stress has a very complex shape and is function of a dimensionless geometrical parameter. Expressions to calculate the true shear stress τ and strain γ from the experimental force-displacement data were proposed. The equations' constants are determined by fitting the experimental curve with the stress τ and strain γ simulation point tracked data.
Measuring Interlayer Shear Stress in Bilayer Graphene

NASA Astrophysics Data System (ADS)

Wang, Guorui; Dai, Zhaohe; Wang, Yanlei; Tan, PingHeng; Liu, Luqi; Xu, Zhiping; Wei, Yueguang; Huang, Rui; Zhang, Zhong

2017-07-01

Monolayer two-dimensional (2D) crystals exhibit a host of intriguing properties, but the most exciting applications may come from stacking them into multilayer structures. Interlayer and interfacial shear interactions could play a crucial role in the performance and reliability of these applications, but little is known about the key parameters controlling shear deformation across the layers and interfaces between 2D materials. Herein, we report the first measurement of the interlayer shear stress of bilayer graphene based on pressurized microscale bubble loading devices. We demonstrate continuous growth of an interlayer shear zone outside the bubble edge and extract an interlayer shear stress of 40 kPa based on a membrane analysis for bilayer graphene bubbles. Meanwhile, a much higher interfacial shear stress of 1.64 MPa was determined for monolayer graphene on a silicon oxide substrate. Our results not only provide insights into the interfacial shear responses of the thinnest structures possible, but also establish an experimental method for characterizing the fundamental interlayer shear properties of the emerging 2D materials for potential applications in multilayer systems.
Rac1 mediates laminar shear stress-induced vascular endothelial cell migration

PubMed Central

Huang, Xianliang; Shen, Yang; Zhang, Yi; Wei, Lin; Lai, Yi; Wu, Jiang; Liu, Xiaojing; Liu, Xiaoheng

2013-01-01

The migration of endothelial cells (ECs) plays an important role in vascular remodeling and regeneration. ECs are constantly subjected to shear stress resulting from blood flow and are able to convert mechanical stimuli into intracellular signals that affect cellular behaviors and functions. The aim of this study is to elucidate the effects of Rac1, which is the member of small G protein family, on EC migration under different laminar shear stress (5.56, 10.02, and 15.27 dyn/cm2). The cell migration distance under laminar shear stress increased significantly than that under the static culture condition. Especially, under relative high shear stress (15.27 dyn/cm2) there was a higher difference at 8 h (P < 0.01) and 2 h (P < 0.05) compared with static controls. RT-PCR results further showed increasing mRNA expression of Rac1 in ECs exposed to laminar shear stress than that exposed to static culture. Using plasmids encoding the wild-type (WT), an activated mutant (Q61L), and a dominant-negative mutant (T17N), plasmids encoding Rac1 were transfected into EA.hy 926 cells. The average net migration distance of Rac1Q61L group increased significantly, while Rac1T17N group decreased significantly in comparison with the static controls. These results indicated that Rac1 mediated shear stress-induced EC migration. Our findings conduce to elucidate the molecular mechanisms of EC migration induced by shear stress, which is expected to understand the pathophysiological basis of wound healing in health and diseases. PMID:24430179
Flux-pinning-induced interfacial shearing and transverse normal stress in a superconducting coated conductor long strip

NASA Astrophysics Data System (ADS)

Jing, Ze; Yong, Huadong; Zhou, Youhe

2012-08-01

In this paper, a theoretical model is proposed to analyze the transverse normal stress and interfacial shearing stress induced by the electromagnetic force in the superconducting coated conductor. The plane strain approach is used and a singular integral equation is derived. By assuming that the critical current density is magnetic field independent and the superconducting film is infinitely thin, the interfacial shearing stress and normal stress in the film are evaluated for the coated conductor during the increasing and decreasing in the transport current, respectively. The calculation results are discussed and compared for the conductor with different substrate and geometry. The results indicate that the coated conductor with stiffer substrate and larger width experiences larger interfacial shearing stress and less normal stress in the film.
Stress Transfer Mechanisms at the Submicron Level for Graphene/Polymer Systems

PubMed Central

2015-01-01

The stress transfer mechanism from a polymer substrate to a nanoinclusion, such as a graphene flake, is of extreme interest for the production of effective nanocomposites. Previous work conducted mainly at the micron scale has shown that the intrinsic mechanism of stress transfer is shear at the interface. However, since the interfacial shear takes its maximum value at the very edge of the nanoinclusion it is of extreme interest to assess the effect of edge integrity upon axial stress transfer at the submicron scale. Here, we conduct a detailed Raman line mapping near the edges of a monolayer graphene flake that is simply supported onto an epoxy-based photoresist (SU8)/poly(methyl methacrylate) matrix at steps as small as 100 nm. We show for the first time that the distribution of axial strain (stress) along the flake deviates somewhat from the classical shear-lag prediction for a region of ∼2 μm from the edge. This behavior is mainly attributed to the presence of residual stresses, unintentional doping, and/or edge effects (deviation from the equilibrium values of bond lengths and angles, as well as different edge chiralities). By considering a simple balance of shear-to-normal stresses at the interface we are able to directly convert the strain (stress) gradient to values of interfacial shear stress for all the applied tensile levels without assuming classical shear-lag behavior. For large flakes a maximum value of interfacial shear stress of 0.4 MPa is obtained prior to flake slipping. PMID:25644121
A new technique for the measurement of surface shear stress vectors using liquid crystal coatings

NASA Technical Reports Server (NTRS)

Reda, Daniel C.; Muratore, J. J., Jr.

1994-01-01

Research has recently shown that liquid crystal coating (LCC) color-change response to shear depends on both shear stress magnitude and direction. Additional research was thus conducted to extend the LCC method from a flow-visualization tool to a surface shear stress vector measurement technique. A shear-sensitive LCC was applied to a planar test surface and illuminated by white light from the normal direction. A fiber optic probe was used to capture light scattered by the LCC from a point on the centerline of a turbulent, tangential-jet flow. Both the relative shear stress magnitude and the relative in-plane view angle between the sensor and the centerline shear vector were systematically varied. A spectrophotometer was used to obtain scattered-light spectra which were used to quantify the LCC color (dominant wavelength) as a function of shear stress magnitude and direction. At any fixed shear stress magnitude, the minimum dominant wavelength was measured when the shear vector was aligned with and directed away from the observer; changes in the relative in-plane view angle to either side of this vector/observer aligned position resulted in symmetric Gaussian increases in measured dominant wavelength. Based on these results, a vector measurement methodology, involving multiple oblique-view observations of the test surface, was formulated. Under present test conditions, the measurement resolution of this technique was found to be +/- 1 deg for vector orientations and +/- 5% for vector magnitudes. An approach t o extend the present methodology to full-surface applications is proposed.
Shear Strength of Square Graphene Nanoribbons beyond Wrinkling

NASA Astrophysics Data System (ADS)

Ragab, Tarek; Basaran, Cemal

2018-04-01

Atomistic modeling of armchair and zigzag graphene nanoribbons (GNRs) has been performed to investigate the post-wrinkling behavior under in-plane (x-y) shear deformation. Simulations were performed at 300 K for square GNRs with size ranging from 2.5 nm to 20 nm. Shear stresses led only to diagonal tension, and wrinkling was not accompanied by any diagonal compressive force. Once the diagonal tension reached its ultimate elastic level, three major stress-relaxing phenomena were observed. The type of stress-relaxing phenomenon involved greatly affected the mechanical behavior in terms of the slope of the stress-strain diagram beyond the elastic range. The results showed that the average slope of the stress-strain relation beyond the ultimate elastic stress decreased with the increase of the GNR size. Moreover, the slope of the shear stress-strain curve beyond the ultimate elastic stress was always greater for armchair than for zigzag GNRs. GNRs can sustain very high plastic shear strains beyond 100% before failure. The ultimate elastic stress can range from 20 GPa to 50 GPa, occurring at shear strain ranging from 52% to 19%. The ultimate elastic stress and strain were inversely proportional to the size of the GNR with a power factor ranging from 0.261 for armchair GNRs to 0.354 for zigzag GNRs due to the decrease in the effective width for diagonal tension.
Shear Strength of Square Graphene Nanoribbons beyond Wrinkling

NASA Astrophysics Data System (ADS)

Ragab, Tarek; Basaran, Cemal

2018-07-01

Atomistic modeling of armchair and zigzag graphene nanoribbons (GNRs) has been performed to investigate the post-wrinkling behavior under in-plane ( x- y) shear deformation. Simulations were performed at 300 K for square GNRs with size ranging from 2.5 nm to 20 nm. Shear stresses led only to diagonal tension, and wrinkling was not accompanied by any diagonal compressive force. Once the diagonal tension reached its ultimate elastic level, three major stress-relaxing phenomena were observed. The type of stress-relaxing phenomenon involved greatly affected the mechanical behavior in terms of the slope of the stress-strain diagram beyond the elastic range. The results showed that the average slope of the stress-strain relation beyond the ultimate elastic stress decreased with the increase of the GNR size. Moreover, the slope of the shear stress-strain curve beyond the ultimate elastic stress was always greater for armchair than for zigzag GNRs. GNRs can sustain very high plastic shear strains beyond 100% before failure. The ultimate elastic stress can range from 20 GPa to 50 GPa, occurring at shear strain ranging from 52% to 19%. The ultimate elastic stress and strain were inversely proportional to the size of the GNR with a power factor ranging from 0.261 for armchair GNRs to 0.354 for zigzag GNRs due to the decrease in the effective width for diagonal tension.

Radiation from Directional Seismic Sources in Laterally Stratified Media with Application to Arctic Ice Cracking Noise

DTIC Science & Technology

1989-05-22

Stress- Strain Relation . . . . . . . . . . . . . . . . . . . . . . . . 88 5.3 Equivalent Transversely Isotropic Elastic Constants for Periodi- cally...a vertical wavenumber parameters for compressional waves. # : vertical wavenumber parameters for shear waves. 6 dip angle, refer to Fig 3.2. E strain ...been pursued along two different lines[1] : First, in terms of body forces ; second, in terms of disconti- nuities in displacement or strain across a
Coda Calibration Tool

DOE Office of Scientific and Technical Information (OSTI.GOV)

Addair, Travis; Barno, Justin; Dodge, Doug

CCT is a Java based application for calibrating 10 shear wave coda measurement models to observed data using a much smaller set of reference moment magnitudes (MWs) calculated from other means (waveform modeling, etc.). These calibrated measurement models can then be used in other tools to generate coda moment magnitude measurements, source spectra, estimated stress drop, and other useful measurements for any additional events and any new data collected in the calibrated region.
Residual shear strength variability as a primary control on movement of landslides reactivated by earthquake-induced ground motion: Implications for coastal Oregon, U.S.

USGS Publications Warehouse

Schulz, William H.; Wang, Gonghui

2014-01-01

Most large seismogenic landslides are reactivations of preexisting landslides with basal shear zones in the residual strength condition. Residual shear strength often varies during rapid displacement, but the response of residual shear zones to seismic loading is largely unknown. We used a ring shear apparatus to perform simulated seismic loading tests, constant displacement rate tests, and tests during which shear stress was gradually varied on specimens from two landslides to improve understanding of coseismic landslide reactivation and to identify shear strength models valid for slow gravitational failure through rapid coseismic failure. The landslides we studied represent many along the Oregon, U.S., coast. Seismic loading tests resulted in (1) catastrophic failure involving unbounded displacement when stresses represented those for the existing landslides and (2) limited to unbounded displacement when stresses represented those for hypothetical dormant landslides, suggesting that coseismic landslide reactivation may be significant during future great earthquakes occurring near the Oregon Coast. Constant displacement rate tests indicated that shear strength decreased exponentially during the first few decimeters of displacement but increased logarithmically with increasing displacement rate when sheared at 0.001 cm s−1 or greater. Dynamic shear resistance estimated from shear strength models correlated well with stresses observed during seismic loading tests, indicating that displacement rate and amount primarily controlled failure characteristics. We developed a stress-based approach to estimate coseismic landslide displacement that utilizes the variable shear strength model. The approach produced results that compared favorably to observations made during seismic loading tests, indicating its utility for application to landslides.
Study of low-velocity impact response of sandwich panels with shear-thickening gel cores

NASA Astrophysics Data System (ADS)

Wang, Yunpeng; Gong, Xinglong; Xuan, Shouhu

2018-06-01

The low-velocity impact response of sandwich panels with shear-thickening gel cores was studied. The impact tests indicated that the sandwich panels with shear-thickening gel cores showed excellent properties of energy dissipation and stress distribution. In comparison to the similar sandwich panels with chloroprene rubber cores and ethylene-propylene-diene monomer cores, the shear-thickening gel cores led to the obviously smaller contact forces and the larger energy absorptions. Numerical modelling with finite element analysis was used to investigate the stress distribution of the sandwich panels with shear-thickening gel cores and the results agreed well with the experimental results. Because of the unique mechanical property of the shear-thickening gel, the concentrated stress on the front facesheets were distributed to larger areas on the back facesheets and the peak stresses were reduced greatly.
Shear-Panel Test Fixture Eliminates Corner Stresses

NASA Technical Reports Server (NTRS)

Kiss, J. J.; Farley, G. L.; Baker, D. J.

1984-01-01

New design eliminates corner stresses while maintaining uniform stress across panel. Shear panel test fixture includes eight frames and eight corner pins. Fixture assembled in two halves with shear panel sandwiched in between. Results generated from this fixture will result in good data base for design of efficient aircraft structures and other applications.
Correlation between vortices and wall shear stress in a curved artery model under pulsatile flow conditions

NASA Astrophysics Data System (ADS)

Cox, Christopher; Plesniak, Michael W.

2017-11-01

One of the most physiologically relevant factors within the cardiovascular system is the wall shear stress. The wall shear stress affects endothelial cells via mechanotransduction and atherosclerotic regions are strongly correlated with curvature and branching in the human vasculature, where the shear stress is both oscillatory and multidirectional. Also, the combined effect of curvature and pulsatility in cardiovascular flows produces unsteady vortices. In this work, our goal is to assess the correlation between multiple vortex pairs and wall shear stress. To accomplish this, we use an in-house high-order flux reconstruction Navier-Stokes solver to simulate pulsatile flow of a Newtonian blood-analog fluid through a rigid 180° curved artery model. We use a physiologically relevant flow rate and generate results using both fully developed and uniform entrance conditions, the latter motivated by the fact that flow upstream to a curved artery may not be fully developed. Under these two inflow conditions, we characterize the evolution of various vortex pairs and their subsequent effect on several wall shear stress metrics. Supported by GW Center for Biomimetics and Bioinspired Engineering.
Anisotropic shear stress patterns predict the orientation of convergent tissue movements in the embryonic heart

PubMed Central

2017-01-01

Myocardial contractility and blood flow provide essential mechanical cues for the morphogenesis of the heart. In general, endothelial cells change their migratory behavior in response to shear stress patterns, according to flow directionality. Here, we assessed the impact of shear stress patterns and flow directionality on the behavior of endocardial cells, the specialized endothelial cells of the heart. At the early stages of zebrafish heart valve formation, we show that endocardial cells are converging to the valve-forming area and that this behavior depends upon mechanical forces. Quantitative live imaging and mathematical modeling allow us to correlate this tissue convergence with the underlying flow forces. We predict that tissue convergence is associated with the direction of the mean wall shear stress and of the gradient of harmonic phase-averaged shear stresses, which surprisingly do not match the overall direction of the flow. This contrasts with the usual role of flow directionality in vascular development and suggests that the full spatial and temporal complexity of the wall shear stress should be taken into account when studying endothelial cell responses to flow in vivo. PMID:29183943
3D FEA of cemented glass fiber and cast posts with various dental cements in a maxillary central incisor.

PubMed

Madfa, Ahmed A; Al-Hamzi, Mohsen A; Al-Sanabani, Fadhel A; Al-Qudaimi, Nasr H; Yue, Xiao-Guang

2015-01-01

This study aimed to analyse and compare the stability of two dental posts cemented with four different luting agents by examining their shear stress transfer through the FEM. Eight three-dimensional finite element models of a maxillary central incisor restored with glass fiber and Ni-Cr alloy cast dental posts. Each dental post was luted with zinc phosphate, Panavia resin, super bond C&B resin and glass ionomer materials. Finite element models were constructed and oblique loading of 100 N was applied. The distribution of shear stress was investigated at posts and cement/dentine interfaces using ABAQUS/CAE software. The peak shear stress for glass fiber post models minimized approximately three to four times of those for Ni-Cr alloy cast post models. There was negligible difference in peak of shear stress when various cements were compared, irrespective of post materials. The shear stress had same trend for all cement materials. This study found that the glass fiber dental post reduced the shear stress concentration at interfacial of post and cement/dentine compared to Ni-Cr alloy cast dental post.
Production of functional proteins: balance of shear stress and gravity

NASA Technical Reports Server (NTRS)

Kaysen, James Howard (Inventor); Hammond, Timothy Grant (Inventor); Goodwin, Thomas John (Inventor)

2004-01-01

The present invention provides a method for production of functional proteins including hormones by renal cells in a three dimensional co-culture process responsive to shear stress using a rotating wall vessel. Natural mixture of renal cells expresses the enzyme 1-a-hydroxylase which can be used to generate the active form of vitamin D: 1,25-diOH vitamin D3. The fibroblast cultures and co-culture of renal cortical cells express the gene for erythropoietin and secrete erythropoietin into the culture supernatant. Other shear stress response genes are also modulated by shear stress, such as toxin receptors megalin and cubulin (gp280). Also provided is a method of treating in-need individual with the functional proteins produced in a three dimensional co-culture process responsive to shear stress using a rotating wall vessel.
Animal models of surgically manipulated flow velocities to study shear stress-induced atherosclerosis.

PubMed

Winkel, Leah C; Hoogendoorn, Ayla; Xing, Ruoyu; Wentzel, Jolanda J; Van der Heiden, Kim

2015-07-01

Atherosclerosis is a chronic inflammatory disease of the arterial tree that develops at predisposed sites, coinciding with locations that are exposed to low or oscillating shear stress. Manipulating flow velocity, and concomitantly shear stress, has proven adequate to promote endothelial activation and subsequent plaque formation in animals. In this article, we will give an overview of the animal models that have been designed to study the causal relationship between shear stress and atherosclerosis by surgically manipulating blood flow velocity profiles. These surgically manipulated models include arteriovenous fistulas, vascular grafts, arterial ligation, and perivascular devices. We review these models of manipulated blood flow velocity from an engineering and biological perspective, focusing on the shear stress profiles they induce and the vascular pathology that is observed. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
Production of functional proteins: balance of shear stress and gravity

NASA Technical Reports Server (NTRS)

Hammond, Timothy Grant (Inventor); Kaysen, James Howard (Inventor); Goodwin, Thomas John (Inventor)

2007-01-01

The present invention provides a method for production of functional proteins including hormones by renal cells in a three dimensional co-culture process responsive to shear stress using a rotating wall vessel. Natural mixture of renal cells expresses the enzyme 1-a-hydroxylase which can be used to generate the active form of vitamin D: 1,25-diOH vitamin D3. The fibroblast cultures and co-culture of renal cortical cells express the gene for erythropoietin and secrete erythropoietin into the culture supernatant. Other shear stress response genes are also modulated by shear stress, such as toxin receptors megalin and cubulin (gp280). Also provided is a method of treating in-need individual with the functional proteins produced in a three dimensional co-culture process responsive to shear stress using a rotating wall vessel.
Turbulent shear stresses in compressible boundary layers

NASA Technical Reports Server (NTRS)

Laderman, A. J.; Demetriades, A.

1979-01-01

Hot-wire anemometer measurements of turbulent shear stresses in a Mach 3 compressible boundary layer were performed in order to investigate the effects of heat transfer on turbulence. Measurements were obtained by an x-probe in a flat plate, zero pressure gradient, two dimensional boundary layer in a wind tunnel with wall to freestream temperature ratios of 0.94 and 0.71. The measured shear stress distributions are found to be in good agreement with previous results, supporting the contention that the shear stress distribution is essentially independent of Mach number and heat transfer for Mach numbers from incompressible to hypersonic and wall to freestream temperature ratios of 0.4 to 1.0. It is also found that corrections for frequency response limitations of the electronic equipment are necessary to determine the correct shear stress distribution, particularly at the walls.
Orbital fluid shear stress promotes osteoblast metabolism, proliferation and alkaline phosphates activity in vitro

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aisha, M.D.; Nor-Ashikin, M.N.K.; DDH, Universiti Teknologi MARA, ShahAlam 40450, Selangor

Prolonged disuse of the musculoskeletal system is associated with reduced mechanical loading and lack of anabolic stimulus. As a form of mechanical signal, the multidirectional orbital fluid shear stress transmits anabolic signal to bone forming cells in promoting cell differentiation, metabolism and proliferation. Signals are channeled through the cytoskeleton framework, directly modifying gene and protein expression. For that reason, we aimed to study the organization of Normal Human Osteoblast (NHOst) cytoskeleton with regards to orbital fluid shear (OFS) stress. Of special interest were the consequences of cytoskeletal reorganization on NHOst metabolism, proliferation, and osteogenic functional markers. Cells stimulated at 250more » RPM in a shaking incubator resulted in the rearrangement of actin and tubulin fibers after 72 h. Orbital shear stress increased NHOst mitochondrial metabolism and proliferation, simultaneously preventing apoptosis. The ratio of RANKL/OPG was reduced, suggesting that orbital shear stress has the potential to inhibit osteoclastogenesis and osteoclast activity. Increase in ALP activity and OCN protein production suggests that stimulation retained osteoblast function. Shear stress possibly generated through actin seemed to hold an anabolic response as osteoblast metabolism and functional markers were enhanced. We hypothesize that by applying orbital shear stress with suitable magnitude and duration as a non-drug anabolic treatment can help improve bone regeneration in prolonged disuse cases. - Highlights: • OFS stress transmits anabolic signals to osteoblasts. • Actin and tubulin fibers are rearranged under OFS stress. • OFS stress increases mitochondrial metabolism and proliferation. • Reduced RANKL/OPG ratio in response to OFS inhibits osteoclastogenesis. • OFS stress prevents apoptosis and stimulates ALP and OCN.« less
Low-Shear modeled microgravity alters the Salmonella enterica serovar typhimurium stress response in an RpoS-independent manner

NASA Technical Reports Server (NTRS)

Wilson, James W.; Ott, C. Mark; Ramamurthy, Rajee; Porwollik, Steffen; McClelland, Michael; Pierson, Duane L.; Nickerson, Cheryl A.

2002-01-01

We have previously demonstrated that low-shear modeled microgravity (low-shear MMG) serves to enhance the virulence of a bacterial pathogen, Salmonella enterica serovar Typhimurium. The Salmonella response to low-shear MMG involves a signaling pathway that we have termed the low-shear MMG stimulon, though the identities of the low-shear MMG stimulon genes and regulatory factors are not known. RpoS is the primary sigma factor required for the expression of genes that are induced upon exposure to different environmental-stress signals and is essential for virulence in mice. Since low-shear MMG induces a Salmonella acid stress response and enhances Salmonella virulence, we reasoned that RpoS would be a likely regulator of the Salmonella low-shear MMG response. Our results demonstrate that low-shear MMG provides cross-resistance to several environmental stresses in both wild-type and isogenic rpoS mutant strains. Growth under low-shear MMG decreased the generation time of both strains in minimal medium and increased the ability of both strains to survive in J774 macrophages. Using DNA microarray analysis, we found no evidence of induction of the RpoS regulon by low-shear MMG but did find that other genes were altered in expression under these conditions in both the wild-type and rpoS mutant strains. Our results indicate that, under the conditions of these studies, RpoS is not required for transmission of the signal that induces the low-shear MMG stimulon. Moreover, our studies also indicate that low-shear MMG can be added to a short list of growth conditions that can serve to preadapt an rpoS mutant for resistance to multiple environmental stresses.
Differential regulation of protease activated receptor-1 and tissue plasminogen activator expression by shear stress in vascular smooth muscle cells

NASA Technical Reports Server (NTRS)

Papadaki, M.; Ruef, J.; Nguyen, K. T.; Li, F.; Patterson, C.; Eskin, S. G.; McIntire, L. V.; Runge, M. S.

1998-01-01

Recent studies have demonstrated that vascular smooth muscle cells are responsive to changes in their local hemodynamic environment. The effects of shear stress on the expression of human protease activated receptor-1 (PAR-1) and tissue plasminogen activator (tPA) mRNA and protein were investigated in human aortic smooth muscle cells (HASMCs). Under conditions of low shear stress (5 dyn/cm2), PAR-1 mRNA expression was increased transiently at 2 hours compared with stationary control values, whereas at high shear stress (25 dyn/cm2), mRNA expression was decreased (to 29% of stationary control; P<0.05) at all examined time points (2 to 24 hours). mRNA half-life studies showed that this response was not due to increased mRNA instability. tPA mRNA expression was decreased (to 10% of stationary control; P<0.05) by low shear stress after 12 hours of exposure and was increased (to 250% of stationary control; P<0.05) after 24 hours at high shear stress. The same trends in PAR-1 mRNA levels were observed in rat smooth muscle cells, indicating that the effects of shear stress on human PAR-1 were not species-specific. Flow cytometry and ELISA techniques using rat smooth muscle cells and HASMCs, respectively, provided evidence that shear stress exerted similar effects on cell surface-associated PAR-1 and tPA protein released into the conditioned media. The decrease in PAR-1 mRNA and protein had functional consequences for HASMCs, such as inhibition of [Ca2+] mobilization in response to thrombin stimulation. These data indicate that human PAR-1 and tPA gene expression are regulated differentially by shear stress, in a pattern consistent with their putative roles in several arterial vascular pathologies.
Effect of mesh distortion on the accuracy of transverse shear stresses and their sensitivity coefficients in multilayered composites

NASA Technical Reports Server (NTRS)

Noor, Ahmed K.; Kim, Yong H.

1995-01-01

A study is made of the effect of mesh distortion on the accuracy of transverse shear stresses and their first-order and second-order sensitivity coefficients in multilayered composite panels subjected to mechanical and thermal loads. The panels are discretized by using a two-field degenerate solid element, with the fundamental unknowns consisting of both displacement and strain components, and the displacement components having a linear variation throughout the thickness of the laminate. A two-step computational procedure is used for evaluating the transverse shear stresses. In the first step, the in-plane stresses in the different layers are calculated at the numerical quadrature points for each element. In the second step, the transverse shear stresses are evaluated by using piecewise integration, in the thickness direction, of the three-dimensional equilibrium equations. The same procedure is used for evaluating the sensitivity coefficients of transverse shear stresses. Numerical results are presented showing no noticeable degradation in the accuracy of the in-plane stresses and their sensitivity coefficients with mesh distortion. However, such degradation is observed for the transverse shear stresses and their sensitivity coefficients. The standard of comparison is taken to be the exact solution of the three-dimensional thermoelasticity equations of the panel.
A rheological model for elastohydrodynamic contacts based on primary laboratory data

NASA Technical Reports Server (NTRS)

Bair, S.; Winer, W. O.

1979-01-01

A shear rheological model based on primary laboratory data is proposed for concentrated contact lubrication. The model is a Maxwell model modified with a limiting shear stress. Three material properties are required: Low shear stress viscosity, limiting elastic shear modulus, and the limiting shear stress the material can withstand. All three are functions of temperature and pressure. In applying the model to EHD contacts the predicted response possesses the characteristics expected from several experiments reported in the literature and, in one specific case where direct comparison could be made, good numerical agreement is shown.
Aeolian Shear Stress Ratio Measurements within Mesquite-Dominated Landscapes of the Chihuahuan Desert, New Mexico, USA

NASA Technical Reports Server (NTRS)

King, James; Nickling, W. G.; Gilliles, J. A.

2006-01-01

A field study was conducted to ascertain the amount of protection that mesquite-dominated communities provide to the surface from wind erosion. The dynamics of the locally accelerated evolution of a mesquite/coppice dune landscape and the undetermined spatial dependence of potential erosion by wind from a shear stress partition model were investigated. Sediment transport and dust emission processes are governed by the amount of protection that can be provided by roughness elements. Although shear stress partition models exist that can describe this, their accuracy has only been tested against a limited dataset because instrumentation has previously been unable to provide the necessary measurements. This study combines the use of meteorological towers and surface shear stress measurements with Irwin sensors to measure the partition of shear stress in situ. The surface shear stress within preferentially aligned vegetation (within coppice dune development) exhibited highly skewed distributions, while a more homogenous surface stress was recorded at a site with less developed coppice dunes. Above the vegetation, the logarithmic velocity profile deduced roughness length (based on 10-min averages) exhibited a distinct correlation with compass direction for the site with vegetation preferentially aligned, while the site with more homogenously distributed vegetation showed very little variation in the roughness length. This distribution in roughness length within an area, defines a distribution of a resolved shear stress partitioning model based on these measurements, ultimately providing potential closure to a previously uncorrelated model parameter.
Turbulence significantly increases pressure and fluid shear stress in an aortic aneurysm model under resting and exercise flow conditions.

PubMed

Khanafer, Khalil M; Bull, Joseph L; Upchurch, Gilbert R; Berguer, Ramon

2007-01-01

The numerical models of abdominal aortic aneurysm (AAA) in use do not take into account the non-Newtonian behavior of blood and the development of local turbulence. This study examines the influence of pulsatile, turbulent, non-Newtonian flow on fluid shear stresses and pressure changes under rest and exercise conditions. We numerically analyzed pulsatile turbulent flow, using simulated physiological rest and exercise waveforms, in axisymmetric-rigid aortic aneurysm models (AAMs). Discretization of governing equations was achieved using a finite element scheme. Maximum turbulence-induced shear stress was found at the distal end of an AAM. In large AAMs (dilated to undilated diameter ratio = 3.33) at peak systolic flow velocity, fluid shear stress during exercise is 70.4% higher than at rest. Our study provides a numerical, noninvasive method for obtaining detailed data on the forces generated by pulsatile turbulent flow in AAAs that are difficult to study in humans and in physical models. Our data suggest that increased flow turbulence results in increased shear stress in aneurysms. While pressure readings are fairly uniform along the length of an aneurysm, the kinetic energy generated by turbulence impacting on the wall of the distal half of the aneurysm increases fluid and wall shear stress at this site. If the increased fluid shear stress results in further dilation and hence further turbulence, wall stress may be a mechanism for aneurysmal growth and eventual rupture.
Aeolian shear stress ratio measurements within mesquite-dominated landscapes of the Chihuahuan Desert, New Mexico, USA

NASA Astrophysics Data System (ADS)

King, James; Nickling, W. G.; Gillies, J. A.

2006-12-01

A field study was conducted to ascertain the amount of protection that mesquite-dominated communities provide to the surface from wind erosion. The dynamics of the locally accelerated evolution of a mesquite/coppice dune landscape and the undetermined spatial dependence of potential erosion by wind from a shear stress partition model were investigated. Sediment transport and dust emission processes are governed by the amount of protection that can be provided by roughness elements. Although shear stress partition models exist that can describe this, their accuracy has only been tested against a limited dataset because instrumentation has previously been unable to provide the necessary measurements. This study combines the use of meteorological towers and surface shear stress measurements with Irwin sensors to measure the partition of shear stress in situ. The surface shear stress within preferentially aligned vegetation (within coppice dune development) exhibited highly skewed distributions, while a more homogenous surface stress was recorded at a site with less developed coppice dunes. Above the vegetation, the logarithmic velocity profile deduced roughness length (based on 10-min averages) exhibited a distinct correlation with compass direction for the site with vegetation preferentially aligned, while the site with more homogenously distributed vegetation showed very little variation in the roughness length. This distribution in roughness length within an area, defines a distribution of a resolved shear stress partitioning model based on these measurements, ultimately providing potential closure to a previously uncorrelated model parameter.

Emergent SO(3) Symmetry of the Frictionless Shear Jamming Transition

NASA Astrophysics Data System (ADS)

Baity-Jesi, Marco; Goodrich, Carl P.; Liu, Andrea J.; Nagel, Sidney R.; Sethna, James P.

2017-05-01

We study the shear jamming of athermal frictionless soft spheres, and find that in the thermodynamic limit, a shear-jammed state exists with different elastic properties from the isotropically-jammed state. For example, shear-jammed states can have a non-zero residual shear stress in the thermodynamic limit that arises from long-range stress-stress correlations. As a result, the ratio of the shear and bulk moduli, which in isotropically-jammed systems vanishes as the jamming transition is approached from above, instead approaches a constant. Despite these striking differences, we argue that in a deeper sense, the shear jamming and isotropic jamming transitions actually have the same symmetry, and that the differences can be fully understood by rotating the six-dimensional basis of the elastic modulus tensor.
Effect of exercise on hemodynamic conditions in the abdominal aorta.

PubMed

Taylor, C A; Hughes, T J; Zarins, C K

1999-06-01

The beneficial effect of exercise in the retardation of the progression of cardiovascular disease is hypothesized to be caused, at least in part, by the elimination of adverse hemodynamic conditions, including flow recirculation and low wall shear stress. In vitro and in vivo investigations have provided qualitative and limited quantitative information on flow patterns in the abdominal aorta and on the effect of exercise on the elimination of adverse hemodynamic conditions. We used computational fluid mechanics methods to examine the effects of simulated exercise on hemodynamic conditions in an idealized model of the human abdominal aorta. A three-dimensional computer model of a healthy human abdominal aorta was created to simulate pulsatile aortic blood flow under conditions of rest and graded exercise. Flow velocity patterns and wall shear stress were computed in the lesion-prone infrarenal aorta, and the effects of exercise were determined. A recirculation zone was observed to form along the posterior wall of the aorta immediately distal to the renal vessels under resting conditions. Low time-averaged wall shear stress was present in this location, along the posterior wall opposite the superior mesenteric artery and along the anterior wall between the superior and inferior mesenteric arteries. Shear stress temporal oscillations, as measured with an oscillatory shear index, were elevated in these regions. Under simulated light exercise conditions, a region of low wall shear stress and high oscillatory shear index remained along the posterior wall immediately distal to the renal arteries. Under simulated moderate exercise conditions, all the regions of low wall shear stress and high oscillatory shear index were eliminated. This numeric investigation provided detailed quantitative data on the effect of exercise on hemodynamic conditions in the abdominal aorta. Our results indicated that moderate levels of lower limb exercise are necessary to eliminate the flow reversal and regions of low wall shear stress in the abdominal aorta that exist under resting conditions. The lack of flow reversal and increased wall shear stress during exercise suggest a mechanism by which exercise may promote arterial health, namely with the elimination of adverse hemodynamic conditions.
Laboratory observations of fault strength in response to changes in normal stress

USGS Publications Warehouse

Kilgore, Brian D.; Lozos, Julian; Beeler, Nicholas M.; Oglesby, David

2012-01-01

Changes in fault normal stress can either inhibit or promote rupture propagation, depending on the fault geometry and on how fault shear strength varies in response to the normal stress change. A better understanding of this dependence will lead to improved earthquake simulation techniques, and ultimately, improved earthquake hazard mitigation efforts. We present the results of new laboratory experiments investigating the effects of step changes in fault normal stress on the fault shear strength during sliding, using bare Westerly granite samples, with roughened sliding surfaces, in a double direct shear apparatus. Previous experimental studies examining the shear strength following a step change in the normal stress produce contradictory results: a set of double direct shear experiments indicates that the shear strength of a fault responds immediately, and then is followed by a prolonged slip-dependent response, while a set of shock loading experiments indicates that there is no immediate component, and the response is purely gradual and slip-dependent. In our new, high-resolution experiments, we observe that the acoustic transmissivity and dilatancy of simulated faults in our tests respond immediately to changes in the normal stress, consistent with the interpretations of previous investigations, and verify an immediate increase in the area of contact between the roughened sliding surfaces as normal stress increases. However, the shear strength of the fault does not immediately increase, indicating that the new area of contact between the rough fault surfaces does not appear preloaded with any shear resistance or strength. Additional slip is required for the fault to achieve a new shear strength appropriate for its new loading conditions, consistent with previous observations made during shock loading.
Erosion characteristics and horizontal variability for small erosion depths in the Sacramento-San Joaquin River Delta, California, USA

NASA Astrophysics Data System (ADS)

Schoellhamer, David H.; Manning, Andrew J.; Work, Paul A.

2017-06-01

Erodibility of cohesive sediment in the Sacramento-San Joaquin River Delta (Delta) was investigated with an erosion microcosm. Erosion depths in the Delta and in the microcosm were estimated to be about one floc diameter over a range of shear stresses and times comparable to half of a typical tidal cycle. Using the conventional assumption of horizontally homogeneous bed sediment, data from 27 of 34 microcosm experiments indicate that the erosion rate coefficient increased as eroded mass increased, contrary to theory. We believe that small erosion depths, erosion rate coefficient deviation from theory, and visual observation of horizontally varying biota and texture at the sediment surface indicate that erosion cannot solely be a function of depth but must also vary horizontally. We test this hypothesis by developing a simple numerical model that includes horizontal heterogeneity, use it to develop an artificial time series of suspended-sediment concentration (SSC) in an erosion microcosm, then analyze that time series assuming horizontal homogeneity. A shear vane was used to estimate that the horizontal standard deviation of critical shear stress was about 30% of the mean value at a site in the Delta. The numerical model of the erosion microcosm included a normal distribution of initial critical shear stress, a linear increase in critical shear stress with eroded mass, an exponential decrease of erosion rate coefficient with eroded mass, and a stepped increase in applied shear stress. The maximum SSC for each step increased gradually, thus confounding identification of a single well-defined critical shear stress as encountered with the empirical data. Analysis of the artificial SSC time series with the assumption of a homogeneous bed reproduced the original profile of critical shear stress, but the erosion rate coefficient increased with eroded mass, similar to the empirical data. Thus, the numerical experiment confirms the small-depth erosion hypothesis. A linear model of critical shear stress and eroded mass is proposed to simulate small-depth erosion, assuming that the applied and critical shear stresses quickly reach equilibrium.
Cyclic Axial-Torsional Deformation Behavior of a Cobalt-Base Superalloy

NASA Technical Reports Server (NTRS)

Bonacuse, Peter J.; Kalluri, Sreeramesh

1995-01-01

The cyclic, high-temperature deformation behavior of a wrought cobalt-base super-alloy, Haynes 188, is investigated under combined axial and torsional loads. This is accomplished through the examination of hysteresis loops generated from a biaxial fatigue test program. A high-temperature axial, torsional, and combined axial-torsional fatigue database has been generated on Haynes 188 at 760 C. Cyclic loading tests have been conducted on uniform gage section tubular specimens in a servohydraulic axial-torsional test rig. Test control and data acquisition were accomplished with a minicomputer. The fatigue behavior of Haynes 188 at 760 C under axial, torsional, and combined axial-torsional loads and the monotonic and cyclic deformation behaviors under axial and torsional loads have been previously reported. In this paper, the cyclic hardening characteristics and typical hysteresis loops in the axial stress versus axial strain, shear stress ,versus engineering shear strain, axial strain versus engineering shear strain. and axial stress versus shear stress spaces are presented for cyclic in-phase and out-of-phase axial-torsional tests. For in-phase tests, three different values of the proportionality constant lambda (the ratio of engineering shear strain amplitude to axial strain amplitude, are examined, viz. 0.86, 1.73, and 3.46. In the out-of-phase tests, three different values of the phase angle, phi (between the axial and engineering shear strain waveforms), are studied, viz., 30, 60, and 90 degrees with lambda equals 1.73. The cyclic hardening behaviors of all the tests conducted on Haynes 188 at 760 C are evaluated using the von Mises equivalent stress-strain and the maximum shear stress-maximum engineering shear strain (Tresca) curves. Comparisons are also made between the hardening behaviors of cyclic axial, torsional, and combined in-phase (lambda = 1.73 and phi = 0) and out-of-phase (lambda = 1.73 and phi = 90') axial-torsional fatigue tests. These comparisons are accomplished through simple Ramberg-Osgood type stress-strain functions for cyclic, axial stress-strain and shear stress-engineering shear strain curves.
Erosion characteristics and horizontal variability for small erosion depths in the Sacramento-San Joaquin River Delta, California, USA

USGS Publications Warehouse

Schoellhamer, David H.; Manning, Andrew J.; Work, Paul A.

2017-01-01

Erodibility of cohesive sediment in the Sacramento-San Joaquin River Delta (Delta) was investigated with an erosion microcosm. Erosion depths in the Delta and in the microcosm were estimated to be about one floc diameter over a range of shear stresses and times comparable to half of a typical tidal cycle. Using the conventional assumption of horizontally homogeneous bed sediment, data from 27 of 34 microcosm experiments indicate that the erosion rate coefficient increased as eroded mass increased, contrary to theory. We believe that small erosion depths, erosion rate coefficient deviation from theory, and visual observation of horizontally varying biota and texture at the sediment surface indicate that erosion cannot solely be a function of depth but must also vary horizontally. We test this hypothesis by developing a simple numerical model that includes horizontal heterogeneity, use it to develop an artificial time series of suspended-sediment concentration (SSC) in an erosion microcosm, then analyze that time series assuming horizontal homogeneity. A shear vane was used to estimate that the horizontal standard deviation of critical shear stress was about 30% of the mean value at a site in the Delta. The numerical model of the erosion microcosm included a normal distribution of initial critical shear stress, a linear increase in critical shear stress with eroded mass, an exponential decrease of erosion rate coefficient with eroded mass, and a stepped increase in applied shear stress. The maximum SSC for each step increased gradually, thus confounding identification of a single well-defined critical shear stress as encountered with the empirical data. Analysis of the artificial SSC time series with the assumption of a homogeneous bed reproduced the original profile of critical shear stress, but the erosion rate coefficient increased with eroded mass, similar to the empirical data. Thus, the numerical experiment confirms the small-depth erosion hypothesis. A linear model of critical shear stress and eroded mass is proposed to simulate small-depth erosion, assuming that the applied and critical shear stresses quickly reach equilibrium.
Studies on Impingement Effects of Low Density Jets on Surfaces — Determination of Shear Stress and Normal Pressure

NASA Astrophysics Data System (ADS)

Sathian, Sarith. P.; Kurian, Job

2005-05-01

This paper presents the results of the Laser Reflection Method (LRM) for the determination of shear stress due to impingement of low-density free jets on flat plate. For thin oil film moving under the action of aerodynamic boundary layer the shear stress at the air-oil interface is equal to the shear stress between the surface and air. A direct and dynamic measurement of the oil film slope is measured using a position sensing detector (PSD). The thinning rate of oil film is directly measured which is the major advantage of the LRM over LISF method. From the oil film slope history, direct calculation of the shear stress is done using a three-point formula. For the full range of experiment conditions Knudsen numbers varied till the continuum limit of the transition regime. The shear stress values for low-density flows in the transition regime are thus obtained using LRM and the measured values of shear show fair agreement with those obtained by other methods. Results of the normal pressure measurements on a flat plate in low-density jets by using thermistors as pressure sensors are also presented in the paper. The normal pressure profiles obtained show the characteristic features of Newtonian impact theory for hypersonic flows.
Modeling changes in rill erodibility and critical shear stress on native surface roads

Treesearch

Randy B. Foltz; Hakjun Rhee; William J. Elliot

2008-01-01

This study investigated the effect of cumulative overland flow on rill erodibility and critical shear stress on native surface roads in central Idaho. Rill erodibility decreased exponentially with increasing cumulative overland flow depth; however, critical shear stress did not change. The study demonstrated that road erodibility on the studied road changes over the...
Long range stress correlations in the inherent structures of liquids at rest

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chowdhury, Sadrul; Abraham, Sneha; Hudson, Toby

2016-03-28

Simulation studies of the atomic shear stress in the local potential energy minima (inherent structures) are reported for binary liquid mixtures in 2D and 3D. These inherent structure stresses are fundamental to slow stress relaxation and high viscosity in supercooled liquids. We find that the atomic shear stress in the inherent structures (IS’s) of both liquids at rest exhibits slowly decaying anisotropic correlations. We show that the stress correlations contribute significantly to the variance of the total shear stress of the IS configurations and consider the origins of the anisotropy and spatial extent of the stress correlations.
Impact of wall shear stress on initial bacterial adhesion in rotating annular reactor

PubMed Central

Saur, Thibaut; Morin, Emilie; Habouzit, Frédéric; Bernet, Nicolas

2017-01-01

The objective of this study was to investigate the bacterial adhesion under different wall shear stresses in turbulent flow and using a diverse bacterial consortium. A better understanding of the mechanisms governing microbial adhesion can be useful in diverse domains such as industrial processes, medical fields or environmental biotechnologies. The impact of wall shear stress—four values ranging from 0.09 to 7.3 Pa on polypropylene (PP) and polyvinyl chloride (PVC)—was carried out in rotating annular reactors to evaluate the adhesion in terms of morphological and microbiological structures. A diverse inoculum consisting of activated sludge was used. Epifluorescence microscopy was used to quantitatively and qualitatively characterize the adhesion. Attached bacterial communities were assessed by molecular fingerprinting profiles (CE-SSCP). It has been demonstrated that wall shear stress had a strong impact on both quantitative and qualitative aspects of the bacterial adhesion. ANOVA tests also demonstrated the significant impact of wall shear stress on all three tested morphological parameters (surface coverage, number of objects and size of objects) (p-values < 2.10−16). High wall shear stresses increased the quantity of attached bacteria but also altered their spatial distribution on the substratum surface. As the shear increased, aggregates or clusters appeared and their size grew when increasing the shears. Concerning the microbiological composition, the adhered bacterial communities changed gradually with the applied shear. PMID:28207869
On the energetics of tensile and shear void coalescences

NASA Astrophysics Data System (ADS)

Wong, W. H.; Guo, T. F.

2015-09-01

This paper investigates the mechanisms of tensile and shear void coalescences in ductile materials from energetics perspective. By examining and comparing the elastic and plastic energies of a voided cell throughout its deformation history, the onset of and final coalescence can be distinctly established. This energy-based approach offers a single unified method and criterion for determining the occurrences of both mechanisms. This paper also reports a novel micromechanics model that considers general stress states described by three macroscopic normal stresses and one macroscopic shear stress. Detailed formulation of the model is presented that includes the homogenization-based derivation and implementation of a 4×4 orthogonal transformation matrix, which relates the macroscopic deformation rate of the cell to displacement rates of non-physical degrees-of-freedom (DOFs), and the polar decomposition of the macroscopic deformation gradient tensor which admits the explicit determination of the logarithmic strain measures and rotation angle. In terms of stress ratios, ρ1 (=Σ11 /Σ22) ,ρ2 (=Σ12 /Σ22) ,ρ3 (=Σ33 /Σ22), it is analytically shown that multiple macroscopic stress states {ρ1 ,ρ2 ,ρ3 } can exist that result in the same stress triaxiality T and Lode parameter L. Specifically, it is shown that for a prescribed pair of T and L and in the absence of shear stress, at most six stress states {ρ1 , 0 ,ρ3 } are possible. On the other extreme in the presence of shear stress, an infinite number of stress states is possible, due to the existence of Mohr's circle for this stress state. This model, together with the proposed energy-based criteria, is used to examine void coalescence under multiple stress-state conditions for any given T and L. Numerical results have shown that the presence of shear stress has a significant effect of reducing the effective strains for the onset of and final void coalescences. In addition, a relationship has also been established between shear angle and effective strain at the onset of shear void coalescence.
Some New Problems on Shells and Thin Structures

NASA Technical Reports Server (NTRS)

Vlasov, V. S.

1949-01-01

Cylindrical shells of arbitrary section, reinforced by longitudinal and transverse members (stringers and ribs) are considered by us, for a sufficiently close spacing of the ribs, as in our previously published papers (references 1 end 2), as thin-walled orthotropic spatial systems at the cross-sections of which only axial (normal and shearing) forces can arise. The longitudinal bending and twisting moments, due to their weak effect on the stress state of the shell, are taken equal to zero. Along the longitudinal sections of the shell there may arise transverse forces in addition to the normal d shearing forces. Under the so-called static assumptions there is taken for the computation model of the shell a thin-walled spatial system consisting along its length (along a generator) of an infinite number of elementary strips capable of bending. Each of these strips is likened to a curved rod operating in each of its sections not only in tension (compression)but also in transverse bending and shear. The interaction between two adjoining transverse strips in the shell expresses itself in the transmission from one strip to the other of only the normal and shearing stresses. The static structure of the computation model here described is shown in figure 1, where the connections through which the normal and shearing stresses transmitted from one transverse strip to smother are indicated schematically by the rods located in the middle surface of the shell. In addition to the static hypothesis we introduce also geometric hypotheses. According to the latter the elongational deformations of the shell along lines parallel to the generator of its middle surface and the shear deformations in the middle surface, as ma+gitudes having . little effect on the state of the fundamental internal forces of the shell, are taken equal to zero. The deformations of the shell in our computational model are such that in the first place the lines of this surface perpendicular to the generator are inextensible at each point end in the second place the angles between the lines of principal curvature (the coordinate lines) which are straight before the deformation remain straight after the deformation.
Avalanches, and evolution of stress and fabric for a cyclically sheared granular material

NASA Astrophysics Data System (ADS)

Wang, Dengming; Bares, Jonathan; Wang, Dong; Behringer, Bob

2015-03-01

Granular materials yield for large enough shear stress, leading to avalanches. We seek to understand the relation between macroscopic avalanches and the the microscopic granular structure. We present an experimental study of a 2D granular material subjected to cyclic pure shear, which we visualized by a photo-elastic technique. We start from a stress-free sample of frictional particles in the shear-jamming regime (ϕS <= ϕ <=ϕJ). We apply multiple cycles of pure shear: shear in one direction, followed by a reversal to the original boundary configuration. The strain is made in small quasi-static steps: after each small step, we obtain polarized and unpolarized images yielding particle-scale forces and locations. Statistical measures of the avalanches are in reasonable agreement with recent mean-field avalanche models by Dahmen et al. (Nature Physics 7, 554 (2011)) The system structure evolves slowly to reduce the stress at the extrema of strain, similar to the relaxation observed by Ren et al. (Phys. Rev. Lett. 110, 018302 (2013)) in a simple shear experiment. To understand how this relaxation occurs, we track the stress and fabric tensors and measures of the strain field over many cycles of shear. Supported by NASA Grant NNX10AU01G, and NSF Grants DMR1206351 and DMS1248071.
Shear Stress Partitioning in Large Patches of Roughness in the Atmospheric Inertial Sublayer

NASA Technical Reports Server (NTRS)

Gillies, John A.; Nickling, William G.; King, James

2007-01-01

Drag partition measurements were made in the atmospheric inertial sublayer for six roughness configurations made up of solid elements in staggered arrays of different roughness densities. The roughness was in the form of a patch within a large open area and in the shape of an equilateral triangle with 60 m long sides. Measurements were obtained of the total shear stress (tau) acting on the surfaces, the surface shear stress on the ground between the elements (tau(sub S)) and the drag force on the elements for each roughness array. The measurements indicated that tau(sub S) quickly reduced near the leading edge of the roughness compared with tau, and a tau(sub S) minimum occurs at a normalized distance (x/h, where h is element height) of approx. -42 (downwind of the roughness leading edge is negative), then recovers to a relatively stable value. The location of the minimum appears to scale with element height and not roughness density. The force on the elements decreases exponentially with normalized downwind distance and this rate of change scales with the roughness density, with the rate of change increasing as roughness density increases. Average tau(sub S): tau values for the six roughness surfaces scale predictably as a function of roughness density and in accordance with a shear stress partitioning model. The shear stress partitioning model performed very well in predicting the amount of surface shear stress, given knowledge of the stated input parameters for these patches of roughness. As the shear stress partitioning relationship within the roughness appears to come into equilibrium faster for smaller roughness element sizes it would also appear the shear stress partitioning model can be applied with confidence for smaller patches of smaller roughness elements than those used in this experiment.
Shear stress-induced mitochondrial biogenesis decreases the release of microparticles from endothelial cells.

PubMed

Kim, Ji-Seok; Kim, Boa; Lee, Hojun; Thakkar, Sunny; Babbitt, Dianne M; Eguchi, Satoru; Brown, Michael D; Park, Joon-Young

2015-08-01

The concept of enhancing structural integrity of mitochondria has emerged as a novel therapeutic option for cardiovascular disease. Flow-induced increase in laminar shear stress is a potent physiological stimulant associated with exercise, which exerts atheroprotective effects in the vasculature. However, the effect of laminar shear stress on mitochondrial remodeling within the vascular endothelium and its related functional consequences remain largely unknown. Using in vitro and in vivo complementary studies, here, we report that aerobic exercise alleviates the release of endothelial microparticles in prehypertensive individuals and that these salutary effects are, in part, mediated by shear stress-induced mitochondrial biogenesis. Circulating levels of total (CD31(+)/CD42a(-)) and activated (CD62E(+)) microparticles released by endothelial cells were significantly decreased (∼40% for both) after a 6-mo supervised aerobic exercise training program in individuals with prehypertension. In cultured human endothelial cells, laminar shear stress reduced the release of endothelial microparticles, which was accompanied by an increase in mitochondrial biogenesis through a sirtuin 1 (SIRT1)-dependent mechanism. Resveratrol, a SIRT1 activator, treatment showed similar effects. SIRT1 knockdown using small-interfering RNA completely abolished the protective effect of shear stress. Disruption of mitochondrial integrity by either antimycin A or peroxisome proliferator-activated receptor-γ coactivator-1α small-interfering RNA significantly increased the number of total, and activated, released endothelial microparticles, and shear stress restored these back to basal levels. Collectively, these data demonstrate a critical role of endothelial mitochondrial integrity in preserving endothelial homeostasis. Moreover, prolonged laminar shear stress, which is systemically elevated during aerobic exercise in the vessel wall, mitigates endothelial dysfunction by promoting mitochondrial biogenesis. Copyright © 2015 the American Physiological Society.
High Nutrient Load Increases Biostabilization of Sediment by Biofilms

NASA Astrophysics Data System (ADS)

Valentine, K.; Mariotti, G.

2016-12-01

Benthic biofilms, matrixes of microbial cells and their secretions, have been shown to stabilize sediment in coastal environments. While there have been numerous studies on the effects of nutrients on the ability of vascular plants to stabilize sediment, few studies have investigated how nutrients affect biofilm growth and their ability to stabilize sediment. Diatom-based biofilms were grown in laboratory experiments on a settled bed of bentonite clay, under a saline water column with varying amounts of nutrients. Erodibility at different stages of biofilm growth was measured using a Gust Erosion Microcosm System, which applied shear stresses from 0.05 to 0.6 Pa. Biofilms more than one week old decreased the erodibility of the sediments in all nutrient treatments compared to abiotic experiments. With high nutrients, the biofilm grew the fastest; the erodibility decreased within two weeks of biofilm growth and remained low for all applied shear stresses. After four weeks of biofilm growth, no erosion of sediment occurred even at the highest applied shear stress (0.6 Pa). With low nutrients the erodibility decreased within three weeks. With no nutrients the biofilms grew similarly to those with low nutrients; the erodibility decreased within three weeks under shear stresses 0.05-0.45 Pa, but the sediments were eroded under high shear stresses. Under low to moderate shear stresses (0.05-0.45 Pa), the total mass eroded by all experiments with biofilms was similar, suggesting that any amount of biofilm decreases erodibility at low shear stresses. In summary, high nutrients allow for faster biostabilization and for resistance to extreme shear stresses. These results suggest that eutrophication would not decrease the biofilm ability to stabilize muddy sediments in coastal environment.
Fan-structure waves in shear ruptures

NASA Astrophysics Data System (ADS)

Tarasov, Boris

2016-04-01

This presentation introduces a recently identified shear rupture mechanism providing a paradoxical feature of hard rocks - the possibility of shear rupture propagation through the highly confined intact rock mass at shear stress levels significantly less than frictional strength. According to the fan-mechanism the shear rupture propagation is associated with consecutive creation of small slabs in the fracture tip which, due to rotation caused by shear displacement of the fracture interfaces, form a fan-structure representing the fracture head. The fan-head combines such unique features as: extremely low shear resistance (below the frictional strength), self-sustaining stress intensification in the rupture tip (providing easy formation of new slabs), and self-unbalancing conditions in the fan-head (making the failure process inevitably spontaneous and violent). An important feature of the fan-mechanism is the fact that for the initial formation of the fan-structure an enhanced local shear stress is required, however, after completion of the fan-structure it can propagate as a dynamic wave through intact rock mass at shear stresses below the frictional strength. Paradoxically low shear strength of pristine rocks provided by the fan-mechanism determines the correspondingly low transient strength of the lithosphere, which favours generation of new earthquake faults in the intact rock mass adjoining pre-existing faults in preference to frictional stick-slip instability along these faults. The new approach reveals an alternative role of pre-existing faults in earthquake activity: they represent local stress concentrates in pristine rock adjoining the fault where special conditions for the fan-mechanism nucleation are created, while further dynamic propagation of the new fault (earthquake) occurs at low field stresses even below the frictional strength.
Shear stress and flow dynamics of the femoral vein among obese patients who qualify for bariatric surgery.

PubMed

Wiewiora, Maciej; Piecuch, Jerzy; Glűck, Marek; Slowinska-Lozynska, Ludmila; Sosada, Krystyn

2013-01-01

The aim of this study was to evaluate the effects of obesity on wall shear stress and its relationship to erythrocyte aggregation. We studied 35 morbidly obese patients who were qualified for bariatric surgery. The control group consisted of 20 non-obese people. Blood rheological measurements were performed using the Laser-assisted Optical Rotational Cell Analyzer (Mechatronics, the Netherlands) and a cone-plate viscometer (Brookfield DV-II). The venous flow dynamics were assessed using a duplex ultrasound. The shear rate was estimated from the measured blood flow velocity and the diameter of the femoral vein. Venous wall shear stress was calculated from the whole blood viscosity and the shear rate. The shear rate (P < 0.005) and the venous wall shear stress (P < 0.05) were significantly lower in obese patients compared with the controls. The aggregation index (P < 0.001), syllectogram amplitude - AMP (P < 0.05) and Tslow (P < 0.001) were significantly higher in the obese patients; the aggregation half-time (P < 0.001) and Tfast (P < 0.001) were decreased compared with the control group. Multivariate regression analyses found waist circumference (β -0.31, P < 0.05), thigh circumference (β 0.33, P < 0.05) and Tslow (β -0.47, P < 0.005) to be variables that independently influenced the shear rate. Nevertheless, the AMP (β 0.34, P < 0.05) and Tslow (β -0.47, P < 0.01) were independent predictors that influenced the wall shear stress. This study indicates that there is a relationship between wall shear stress in the femoral vein and the rheological impairment of the RBC among obese patients, but further studies are necessary to confirm this suggestion.
Wall shear stress measurement in blade end-wall corner region

NASA Technical Reports Server (NTRS)

Bhargava, R.; Raj, R.; Boldman, D. R.

1987-01-01

The magnitude and the direction of wall shear stress and surface pressure in the blade end-wall corner region were investigated. The measurements were obtained on a specially designed Preston tube, the tip of which could be concentrically rotated about its axis of rotation at the measurement location. The magnitude of wall shear stress in the vicinity of the corner was observed to increase significantly (170 percent) compared to its far-upstream value; the increase was consistently higher on the blade surface compared to the value on the plate surface of the blade end-wall corner. On both surfaces in the blade end-wall corner, the variation of the wall shear stress direction was found to be more predominant in the vicinity of the blade leading-edge location. The trend of the measured wall shear stress direction showed good agreement with the limiting streamline directions obtained from the flow visualization studies.
An equilibrium method for prediction of transverse shear stresses in a thick laminated plate

NASA Technical Reports Server (NTRS)

Chaudhuri, R. Z.

1986-01-01

First two equations of equilibrium are utilized to compute the transverse shear stress variation through thickness of a thick laminated plate after in-plane stresses have been computed using an assumed quadratic displacement triangular element based on transverse inextensibility and layerwise constant shear angle theory (LCST). Centroid of the triangle is the point of exceptional accuracy for transverse shear stresses. Numerical results indicate close agreement with elasticity theory. An interesting comparison between the present theory and that based on assumed stress hybrid finite element approach suggests that the latter does not satisfy the condition of free normal traction at the edge. Comparison with numerical results obtained by using constant shear angle theory suggests that LCST is close to the elasticity solution while the CST is closer to classical (CLT) solution. It is also demonstrated that the reduced integration gives faster convergence when the present theory is applied to a thin plate.

A Multi-scale Refined Zigzag Theory for Multilayered Composite and Sandwich Plates with Improved Transverse Shear Stresses

NASA Technical Reports Server (NTRS)

Iurlaro, Luigi; Gherlone, Marco; Di Sciuva, Marco; Tessler, Alexander

2013-01-01

The Refined Zigzag Theory (RZT) enables accurate predictions of the in-plane displacements, strains, and stresses. The transverse shear stresses obtained from constitutive equations are layer-wise constant. Although these transverse shear stresses are generally accurate in the average, layer-wise sense, they are nevertheless discontinuous at layer interfaces, and thus they violate the requisite interlaminar continuity of transverse stresses. Recently, Tessler applied Reissner's mixed variational theorem and RZT kinematic assumptions to derive an accurate and efficient shear-deformation theory for homogeneous, laminated composite, and sandwich beams, called RZT(m), where "m" stands for "mixed". Herein, the RZT(m) for beams is extended to plate analysis, where two alternative assumptions for the transverse shear stresses field are examined: the first follows Tessler's formulation, whereas the second is based on Murakami's polynomial approach. Results for elasto-static simply supported and cantilever plates demonstrate that Tessler's formulation results in a powerful and efficient structural theory that is well-suited for the analysis of multilayered composite and sandwich panels.
Normal stresses in shear thickening granular suspensions.

PubMed

Pan, Zhongcheng; de Cagny, Henri; Habibi, Mehdi; Bonn, Daniel

2017-05-24

When subjected to shear, granular suspensions exhibit normal stresses perpendicular to the shear plane but the magnitude and sign of the different components of the normal stresses are still under debate. By performing both oscillatory and rotational rheology measurements on shear thickening granular suspensions and systematically varying the particle diameters and the gap sizes between two parallel-plates, we show that a transition from a positive to a negative normal stress can be observed. We find that frictional interactions which determine the shear thickening behavior of suspensions contribute to the positive normal stresses. Increasing the particle diameters or decreasing the gap sizes leads to a growing importance of hydrodynamic interactions, which results in negative normal stresses. We determine a relaxation time for the system, set by both the pore and the gap sizes, that governs the fluid flow through the inter-particle space. Finally, using a two-fluid model we determine the relative contributions from the particle phase and the liquid phase.
The Effect of Humidity and Particle Characteristics on Friction and Stick-slip Instability in Granular Fault Gouge

NASA Astrophysics Data System (ADS)

Anthony, J. L.; Marone, C. J.

2003-12-01

Previous studies have shown that particle characteristics such as shape, dimension, and roughness affect friction in granular shear zones. Other work shows that humidity plays a key role in frictional healing and rate/state dependence within granular gouge. In order to improve our understanding of grain-scale deformation mechanisms within fault gouge, we performed laboratory experiments using a double-direct-shear testing apparatus. This assembly includes three rigid forcing blocks with two gouge layers sandwiched between rough or smooth surfaces. Roughened surfaces were triangular grooves 0.8 mm deep and 1 mm wavelength. These promote distributed shear throughout the layer undergoing cataclastic deformation. Smooth surfaces were mirror-finished hardened steel and were used to promote and isolate grain boundary sliding. The center block is forced at controlled displacement rate between the two side blocks to create frictional shear. We studied gouge layers 3-7 mm thick, consisting of either quartz rods sheared in 1-D and 2-D configurations and smooth glass beads mixed with varying amounts of rough sand particles. We report on particle diameters that range from 0.050-0.210 mm, and quartz rods 1 mm in diameter and 100 mm long. The experiments are run at room temperature, controlled relative humidity ranging from 5 to 100%, and shear displacement rates from 0.1 to 300 microns per second. Experiments are carried out under a normal stress of 5 MPa, a non-fracture loading regime where sliding friction for smooth spherical particles is measurably lower than for rough angular particles. We compare results from shear between smooth boundaries, where we hypothesize that grain boundary sliding is the mechanism influencing granular friction, to rough sample experiments where shear undergoes a transition from distributed, pervasive shear to progressively localized as a function of increasing strain. For shear within rough surfaces, stick-slip instability occurs in gouge that consists of less than 30% angular grains and begins once the coefficient of friction (shear stress divided by normal stress) reaches a value of 0.35-0.40. Peak friction during stick-slip cycles is 0.40-0.45. Each stick-slip event involves a small amount of quasi-static displacement prior to failure, which we refer to as pre-seismic slip. For unstable sliding regimes, we measure the amount of pre-seismic slip and the magnitude of dynamic stress drop. These parameters vary systematically with sliding velocity, particle characteristics, and bounding roughness. For shear within smooth surfaces, friction is very low (0.15-0.16 for spherical particles) and sliding is stable, without stick-slip instability. As more angular grains are mixed with spherical beads the coefficient of friction increases. This holds true for both the rough and smooth sample experiments. We expand on previous work done by Frye and Marone 2002 (JGR) to study the effect of humidity on 1-D, 2-D, and 3-D gouge layer configurations. Our data show that humidity has a significant effect on frictional strength and stability and that this effect is observed for both smooth surfaces, where grain boundary sliding is the dominant deformation mechanisms, and for shear within rough surfaces where gouge deformation occurs by rolling, dilation, compaction, and grain boundary sliding.
An evaluation of the Iosipescu specimen for composite materials shear property measurement

NASA Technical Reports Server (NTRS)

Morton, J.; Ho, H.; Tsai, M. Y.; Farley, G. L.

1992-01-01

A detailed evaluation of the suitability of the Iosipescu specimen tested in the modified Wyoming fixture is presented. A linear finite element model of the specimen is used to assess the uniformity of the shear stress field in the vicinity of the notch, and demonstrate the effect of the nonuniform stress field upon strain gage measurements used for the determination of composite shear moduli. Based upon test results from graphite-epoxy laminates, the proximity of the load introduction point to the test section and the material orthotropy greatly influence the individual gage readings, however, shear modulus determination is not significantly affected by the lack of pure shear. Correction factors are needed to allow for the nonuniformity of the strain field and the use of the average shear stress in the shear modulus evaluation. The correction factors are determined for the region occupied by the strain gage rosette. A comparison of the strain gage readings from one surface of a specimen with corresponding data from moire interferometry on the opposite face documented an extreme sensitivity of some fiber orientations to eccentric loading which induced twisting and spurious shear stress-strain curves. The discovery of specimen twisting explains the apparently inconsistent shear property data found in the literature. Recommendations for improving the reliability and accuracy of the shear modulus values are made, and the implications for shear strength measurement discussed.
Molecular characteristics of stress overshoot for polymer melts under start-up shear flow.

PubMed

Jeong, Sohdam; Kim, Jun Mo; Baig, Chunggi

2017-12-21

Stress overshoot is one of the most important nonlinear rheological phenomena exhibited by polymeric liquids undergoing start-up shear at sufficient flow strengths. Despite considerable previous research, the fundamental molecular characteristics underlying stress overshoot remain unknown. Here, we analyze the intrinsic molecular mechanisms behind the overshoot phenomenon using atomistic nonequilibrium molecular dynamics simulations of entangled linear polyethylene melts under shear flow. Through a detailed analysis of the transient rotational chain dynamics, we identify an intermolecular collision angular regime in the vicinity of the chain orientation angle θ ≈ 20° with respect to the flow direction. The shear stress overshoot occurs via strong intermolecular collisions between chains in the collision regime at θ = 15°-25°, corresponding to a peak strain of 2-4, which is an experimentally well-known value. The normal stress overshoot appears at approximately θ = 10°, at a corresponding peak strain roughly equivalent to twice that for the shear stress. We provide plausible answers to several basic questions regarding the stress overshoot, which may further help understand other nonlinear phenomena of polymeric systems.
Failure Mechanisms of Brittle Rocks under Uniaxial Compression

NASA Astrophysics Data System (ADS)

Liu, Taoying; Cao, Ping

2017-09-01

The behaviour of a rock mass is determined not only by the properties of the rock matrix, but mostly by the presence and properties of discontinuities or fractures within the mass. The compression test on rock-like specimens with two prefabricated transfixion fissures, made by pulling out the embedded metal inserts in the pre-cured period was carried out on the servo control uniaxial loading tester. The influence of the geometry of pre-existing cracks on the cracking processes was analysed with reference to the experimental observation of crack initiation and propagation from pre-existing flaws. Based on the rock fracture mechanics and the stress-strain curves, the evolution failure mechanism of the fissure body was also analyzed on the basis of exploring the law of the compression-shear crack initiation, wing crack growth and rock bridge connection. Meanwhile, damage fracture mechanical models of a compression-shear rock mass are established when the rock bridge axial transfixion failure, tension-shear combined failure, or wing crack shear connection failure occurs on the specimen under axial compression. This research was of significance in studying the failure mechanism of fractured rock mass.
Investigation of interfacial shear strength in a SiC fibre/Ti-24Al-11Nb composite by a fibre push-out technique

NASA Technical Reports Server (NTRS)

Eldridge, J. I.; Brindley, P. K.

1989-01-01

A fiber push-out technique applied at several sample thicknesses was used to determine both the debond shear stress and the frictional shear stress at the fiber-matrix interface at room temperautre for a unidirectional SiC fiber-reinforced T-24Al-11Nb (in at. pct) composite prepared by a powder cloth technique. The push-out technique measures the separate contributions of bond strength and friction to the mechanical shear strength at the fiber-matrix interface. It was found that the fiber-matrix bond shear strength of this material is significantly higher than the fiber-matrix frictional shear stress (119.2 and 47.8 MPa, respectively).
Stochastic characteristics and Second Law violations of atomic fluids in Couette flow

NASA Astrophysics Data System (ADS)

Raghavan, Bharath V.; Karimi, Pouyan; Ostoja-Starzewski, Martin

2018-04-01

Using Non-equilibrium Molecular Dynamics (NEMD) simulations, we study the statistical properties of an atomic fluid undergoing planar Couette flow, in which particles interact via a Lennard-Jones potential. We draw a connection between local density contrast and temporal fluctuations in the shear stress, which arise naturally through the equivalence between the dissipation function and entropy production according to the fluctuation theorem. We focus on the shear stress and the spatio-temporal density fluctuations and study the autocorrelations and spectral densities of the shear stress. The bispectral density of the shear stress is used to measure the degree of departure from a Gaussian model and the degree of nonlinearity induced in the system owing to the applied strain rate. More evidence is provided by the probability density function of the shear stress. We use the Information Theory to account for the departure from Gaussian statistics and to develop a more general probability distribution function that captures this broad range of effects. By accounting for negative shear stress increments, we show how this distribution preserves the violations of the Second Law of Thermodynamics observed in planar Couette flow of atomic fluids, and also how it captures the non-Gaussian nature of the system by allowing for non-zero higher moments. We also demonstrate how the temperature affects the band-width of the shear-stress and how the density affects its Power Spectral Density, thus determining the conditions under which the shear-stress acts is a narrow-band or wide-band random process. We show that changes in the statistical characteristics of the parameters of interest occur at a critical strain rate at which an ordering transition occurs in the fluid causing shear thinning and affecting its stability. A critical strain rate of this kind is also predicted by the Loose-Hess stability criterion.
Methodology for calculating shear stress in a meandering channel

Treesearch

Kyung-Seop Sin

2010-01-01

Shear stress in meandering channels is the key parameter to predict bank erosion and bend migration. A representative study reach of the Rio Grande River in central New Mexico has been modeled in the Hydraulics Laboratory at CSU. To determine the shear stress distribution in a meandering channel, the large scale (1:12) physical modeling study was conducted in the...
Development of a shear stress sensor to analyse the influence of polymers on the turbulent wall shear stress.

PubMed

Nottebrock, Bernardo; Grosse, Sebastian; Schröder, Wolfgang

2011-05-11

The drag reducing effect of polymers in a channel flow is well known and it is assumed that the polymer filaments interfere with the turbulent structures in the very near-wall flow. To analyse their precise effect, a micro-pillar shear stress sensor (MPS³) measurement system is developed which allows the detection of wall shear stress at high spatial and temporal resolutions. Different manufacturing techniques for the required micro-pillars are discussed and their influence on the flow is investigated evidencing the non-intrusive character of the pillars. Subsequently, a complete calibration is presented to relate the recorded deflection to wall shear stress values and to assure the correct detection over the whole expected frequency spectrum. A feasibility study about the ability to visualize the two-dimensional wall shear stress distribution completes the discussion about the validity of MPS³. In the last step, the drag reduction of a polymer filament grafted on a micro-pillar compared to a plain pillar and the application of MPS³ in an ocean-type polymer solution are investigated. The results confirm the expected behaviour found in the literature.
Investigation of Wall Shear Stress Behavior for Rough Surfaces with Blowing

NASA Astrophysics Data System (ADS)

Helvey, Jacob; Borchetta, Colby; Miller, Mark; Martin, Alexandre; Bailey, Sean

2014-11-01

We present an experimental study conducted in a turbulent channel flow wind tunnel to determine the modifications made to the turbulent flow over rough surfaces with flow injection through the surfaces. Hot-wire profile results from a quasi-two-dimensional, sinusoidally-rough surface indicate that the effects of roughness are enhanced by momentum injection through the surface. In particular, the wall shear stress was found to show behavior consistent with increased roughness height when surface blowing was increased. This observed behavior contradicts previously reported results for regular three-dimensional roughness which show a decrease in wall shear stress with additional blowing. It is unclear whether this discrepancy is due to differences in the roughness geometry under consideration or the use of the Clauser fit to estimate wall shear stress. Additional PIV experiments are being conducted for a three-dimensional fibrous surface to obtain Reynolds shear stress profiles. These results provide an additional method for estimation of wall-shear stress and thus allow verification of the use of the Clauser chart approach for flows with momentum injection through the surface. This research is supported by NASA Kentucky EPSCoR Award NNX10AV39A, and NASA RA Award NNX13AN04A.
An easy to assemble microfluidic perfusion device with a magnetic clamp

PubMed Central

Tkachenko, Eugene; Gutierrez, Edgar; Ginsberg, Mark H.; Groisman, Alex

2009-01-01

We have built and characterized a magnetic clamp for reversible sealing of PDMS microfluidic chips against cover glasses with cell cultures and a microfluidic chip for experiments on shear stress response of endothelial cells. The magnetic clamp exerts a reproducible uniform pressure on the microfluidic chip, achieving fast and reliable sealing for liquid pressures up to 40 kPa inside the chip with <10% deformations of microchannels and minimal variations of the substrate shear stress in perfusion flow. The microfluidic chip has 8 test regions with the substrate shear stress varying by a factor of 2 between each region, thus covering a 128-fold range from low venous to arterial. The perfusion is driven by differential pressure, which makes it possible to create pulsatile flows mimicking pulsing in the vasculature. The setup is tested by 15 – 40 hours perfusions over endothelial monolayers with shear stress in the range of 0.07 - 9 dyn/cm2. Excellent cell viability at all shear stresses and alignment of cells along the flow at high shear stresses are repeatedly observed. A scratch wound healing assay under a shear flow is demonstrated and cell migration velocities are measured. Transfection of cells with a fluorescent protein is performed, and migrating fluorescent cells are imaged at a high resolution under shear flow in real time. The magnetic clamp can be closed with minimal mechanical perturbation to cells on the substrate and used with a variety of microfluidic chips for experiments with adherent and non-adherent cells. PMID:19350090
Near-wall similarity in a pressure-driven three-dimensional turbulent boundary layer

NASA Technical Reports Server (NTRS)

Pierce, F. J.; Mcallister, J. E.

1980-01-01

Mean velocity, measured wall pressure and wall shear stress fields were made in a three dimensional pressure-driven turbulent boundary layer created by a cylinder with trailing edge placed normal to a flat plate floor. The direct force wall shear stress measurements were made with floating element direct force sensing shear meter that responded to both the magnitude and direction of the local wall shear stress. The ability of 10 near wall similarity models to describe the near wall velocity field for the measured flow under a wide range of skewing conditions and a variety of pressure gradient and wall shear vector orientations was used.
Subscale Development of Advanced ABM Graphite/Epoxy Composite Structure

DTIC Science & Technology

1978-01-01

laminate analysis computer code (Reference 5). eie output of this code yields lamina stresses and strains, equivalent elastic and shear modulii for the...was not accounted for. Therefore the net effect was that the analysis tended to yield conservative results. For design purposes, this conservative...extracted using a Soxhlet Extraction apparatus, recycling the solvent af least 4 to 10 times every hour for a minimum of 6 hours. (4) All samples are
Periodic Viscous Shear Heating Instability in Fine-Grained Shear Zones: Possible Mechanism for Intermediate Depth Earthquakes and Slow Earthquakes?

NASA Astrophysics Data System (ADS)

Kelemen, P. B.; Hirth, G.

2004-12-01

Localized ductile shear zones with widths of cm to m are observed in exposures of Earth's shallow mantle (e.g., Kelemen & Dick JGR 95; Vissers et al. Tectonophys 95) and dredged from oceanic fracture zones (e.g., Jaroslow et al. Tectonophys 96). These are mylonitic (grain size 10 to 100 microns) and record mineral cooling temperatures from 1100 to 600 C. Pseudotachylites in a mantle shear zone show that shear heating temperatures can exceed the mantle solidus (e.g., Obata & Karato Tectonophys 95). Simple shear, recrystallization, and grain boundary sliding all decrease the spacing between pyroxenes, so olivine grain growth at lower stress is inhibited; thus, once formed, these shear zones do not "heal" on geological time scales. Reasoning that grain-size sensitive creep will be localized within these shear zones, rather than host rocks (grain size 1 to 10 mm), and inspired by the work of Whitehead & Gans (GJRAS 74), we thought these might undergo repeated shear heating instabilities. In this view, as elastic stress increases, the shear zone weakens via shear heating; rapid deformation of the weak shear zone releases most stored elastic stress; lower stress and strain rate coupled with diffusion of heat into host rocks leads to cooling and strengthening, after which the cycle repeats. We constructed a simple numerical model incorporating olivine flow laws for dislocation creep, diffusion creep, grain boundary sliding, and low T plasticity. We assumed that viscous deformation remains localized in shear zones, surrounded by host rocks undergoing elastic deformation. We fixed the velocity along one side of an elastic half space, and calculated stress due to elastic strain. This stress drives viscous deformation in a shear zone of specified width. Shear heating and thermal diffusion control temperature evolution in the shear zone and host rocks. A maximum of 1400 C (where substantial melting of peridotite would occur) is imposed. Grain size evolves during dislocation creep and grain boundary sliding as a function of stress and strain, and undergoes diffusive growth during diffusion creep. For strain rates ca E-13 per second and initial temperatures ca 600 to 850 C, this model produces periodic viscous shear heating events with periods of 100's of years. Strain rates during these events approach 1 per second as temperatures reach 1400 C, so future models will incorporate inertial terms in the stress. Cooling between events returns the shear zone almost to its initial temperature, but ultimately shear zone temperature between events exceeds 850 C resulting in stable viscous creep. Back of the envelope calculations based on model results support the view that viscous deformation in both shear zone and host will be mainly via grain-size sensitive creep, and thus deformation will remain localized in shear zones. Similarly, we infer that inertial terms will remain small. Future models will test and quantify these inferences. The simple model described above provides an attractive explanation for intermediate-depth earthquakes, especially those in subduction zones that occur in a narrow thermal window (e.g., Hacker et al JGR 2003). We think that a "smoother"periodic instability might be produced via the same mechanism in weaker materials, which could provide a viscous mechanism for some slow earthquakes. By AGU, we will construct a second, simple model using quartz rheology to investigate this. Finally, coupling of viscous shear heating instabilities in the shallow mantle with brittle stick-slip deformation in the weaker, overlying crust may influence earthquake frequency.
Evaluation of critical shear stresses for consolidated cohesive sediment depositions by using PIV compared with field measurements

NASA Astrophysics Data System (ADS)

Harb, Gabriele; Haun, Stefan

2013-04-01

Reservoir sedimentation is a common problem today. Due to the reduced flow velocities, turbulences and bed shear stresses the transported sediment load start to settle. These depositions reduce the worldwide average storage capacity in the range of about 1% per year. However, depending on the climate conditions and the geology in the catchment area this value may vary strongly. Therefore sediment management tasks, especially the removal of already accumulated sediments, have to be developed for each reservoir separately. The critical bed shear stress is a key parameter used to evaluate the different management tasks and depend strongly on the grain size distribution of the inflowing sediments. However, depositions which contain fine particles like clay and silt increase the critical bed shear stress due to occurring cohesive forces and the use of the Shield curve for evaluating the critical shear stress is no longer valid. Additional data is required for estimating the valid critical shear stress at the reservoir bed. In this study the critical shear stress was evaluated for cohesive sediment samples, taken from two different reservoirs, in a flume in the laboratory. The sediment samples were placed in an installed double bottom in the research flume and the discharge was increased stepwise until mass erosion took place (determined by visual inspection). A 2D PIV device was used to measure the flow conditions (velocities and turbulences) over the sediment sample. The obtained values were used to calculate the bed shear stress for the specific discharge rate by the gravity method and the Reynolds stress method. The results of both methods showed good agreement in the comparison of the values, what indicates that nearly uniform flow conditions occurred in the flume. The results from this study showed that the behaviour of natural cohesive sediments depend strongly on the natural conditions as a result of physical, chemical and biological processes. In this case especially the effect of the layer structure in the sediment samples was controlling the erosion mechanism. The results of the experiments showed also that the obtained average shear stress was above most of the values found in previous conducted studies, which may be explained by consolidation effects in the reservoirs. Additional conducted vane strength measurements have been carried out in situ. The in the field obtained vane strength values were set in relation to the critical shear stresses derived by the experimental tests from the laboratory and to data from a previous conducted study to develop a new relation function. This function may be used in future studies for a rough estimation of the critical shear stress, based on in situ measured vane strength values.
Pressure prediction in non-uniaxial settings based on field data and geomechanical modeling: a well example

NASA Astrophysics Data System (ADS)

Lockhart, L. P.; Flemings, P. B.; Nikolinakou, M. A.; Heidari, M.

2016-12-01

We apply a new pressure prediction approach that couples sonic velocity data, geomechanical modeling, and a critical state soil model to estimate pore pressure from wellbore data adjacent to a salt body where the stress field is complex. Specifically, we study pressure and stress in front of the Mad Dog salt body, in the Gulf of Mexico. Because of the loading from the salt, stresses are not uniaxial; the horizontal stress is elevated, leading to higher mean and shear stresses. For the Mad Dog field, we develop a relationship between velocity and equivalent effective stress, in order to account for both the mean and shear stress effect on pore pressure. We obtain this equivalent effective stress using a geomechanical model of the Mad Dog field. We show that the new approach improves pressure prediction in areas near salt where mean and shear stress are different than the control well. Our methodology and results show that pore pressure is driven by a combination of mean stress and shear stress, and highlight the importance of shear-induced pore pressures. Furthermore, the impact of our study extends beyond salt bodies; the methodology and gained insights are applicable to geological environments around the world with a complex geologic history, where the stress state is not uniaxial (fault zones, anticlines, synclines, continental margins, etc.).
Influence of thickness and permeability of endothelial surface layer on transmission of shear stress in capillaries

NASA Astrophysics Data System (ADS)

Zhang, SongPeng; Zhang, XiangJun; Tian, Yu; Meng, YongGang; Lipowsky, Herbert

2015-07-01

The molecular coating on the surface of microvascular endothelium has been identified as a barrier to transvascular exchange of solutes. With a thickness of hundreds of nanometers, this endothelial surface layer (ESL) has been treated as a porous domain within which fluid shear stresses are dissipated and transmitted to the solid matrix to initiate mechanotransduction events. The present study aims to examine the effects of the ESL thickness and permeability on the transmission of shear stress throughout the ESL. Our results indicate that fluid shear stresses rapidly decrease to insignificant levels within a thin transition layer near the outer boundary of the ESL with a thickness on the order of ten nanometers. The thickness of the transition zone between free fluid and the porous layer was found to be proportional to the square root of the Darcy permeability. As the permeability is reduced ten-fold, the interfacial fluid and solid matrix shear stress gradients increase exponentially two-fold. While the interfacial fluid shear stress is positively related to the ESL thickness, the transmitted matrix stress is reduced by about 50% as the ESL thickness is decreased from 500 to 100 nm, which may occur under pathological conditions. Thus, thickness and permeability of the ESL are two main factors that determine flow features and the apportionment of shear stresses between the fluid and solid phases of the ESL. These results may shed light on the mechanisms of force transmission through the ESL and the pathological events caused by alterations in thickness and permeability of the ESL.
Factors Associated With Callus in Patients with Diabetes, Focused on Plantar Shear Stress During Gait.

PubMed

Hamatani, Masako; Mori, Taketoshi; Oe, Makoto; Noguchi, Hiroshi; Takehara, Kimie; Amemiya, Ayumi; Ohashi, Yumiko; Ueki, Kohjiro; Kadowaki, Takashi; Sanada, Hiromi

2016-11-01

The aim of this study is to identify whether plantar shear stress in neuropathic patients with diabetes with callus is increased compared with those without callus. The differences in foot deformity, limited joint mobility, repetitive stress of walking, and ill-fitting shoes between patients with callus and those without callus were also determined. Subjects were recruited from the Diabetic Foot Outpatient Clinic. A newly developed in-shoe measurement system, which has flexible and thin insoles, enabled measurement of both plantar pressure and shear stress simultaneously when subjects walked as usual on a 10 m walkway. It was found that plantar shear stress adjusted for weight during the push-off phase was increased by 1.32 times in patients with callus compared with those without callus (mean ± SD: 0.0500 ± 0.0160 vs 0.0380 ± 0.0144, P = .031). Moreover, hallux valgus deformity, reduction in dorsiflexion of the ankle joint and increase in plantar flexion were showed in feet with callus. Increased plantar shear stress may be caused by gait change that patients having callus push off with the metatarsal head instead of the toe as a result of foot deformity and limited joint mobility. It was found that plantar shear stress adjusted for weight during the push-off phase was increased in patients with callus compared with those without callus by using the newly developed measurement system. These results suggest that reduction of plantar shear stress during the push-off phase can prevent callus formation in neuropathic patients with diabetes. © 2016 Diabetes Technology Society.
A Microfluidic-Based Multi-Shear Device for Investigating the Effects of Low Fluid-Induced Stresses on Osteoblasts

PubMed Central

Yu, Weiliang; Qu, Hong; Hu, Guoqing; Zhang, Qian; Song, Kui; Guan, Haijie; Liu, Tingjiao; Qin, Jianhua

2014-01-01

Interstitial fluid flow (IFF) within the extracellular matrix (ECM) produces low magnitude shear stresses on cells. Fluid flow-induced stress (FSS) plays an important role during tissue morphogenesis. To investigate the effect of low FSS generated by IFF on cells, we developed a microfluidic-based cell culture device that can generate multiple low shear stresses. By changing the length and width of the flow-in channels, different continuous low level shear stresses could be generated in individual cell culture chambers. Numerical calculations demonstrate uniform shear stress distributions of the major cell culture area of each chamber. This calculation is further confirmed by the wall shear stress curves. The effects of low FSS on MC3T3-E1 proliferation and differentiation were studied using this device. It was found that FSS ranging from 1.5 to 52.6 µPa promoted MC3T3-E1 proliferation and differentiation, but FSS over 412 µPa inhibited the proliferation and differentiation of MC3T3-E1 cells. FSS ranging from 1.5 to 52.6 µPa also increased the expression of Runx2, a key transcription factor regulating osteoblast differentiation. It is suggested that Runx2 might be an important regulator in low FSS-induced MC3T3-E1 differentiation. This device allows for detailed study of the effect of low FSS on the behaviors of cells; thus, it would be a useful tool for analysis of the effects of IFF-induced shear stresses on cells. PMID:24587156

Sustained expression of MCP-1 by low wall shear stress loading concomitant with turbulent flow on endothelial cells of intracranial aneurysm.

PubMed

Aoki, Tomohiro; Yamamoto, Kimiko; Fukuda, Miyuki; Shimogonya, Yuji; Fukuda, Shunichi; Narumiya, Shuh

2016-05-09

Enlargement of a pre-existing intracranial aneurysm is a well-established risk factor of rupture. Excessive low wall shear stress concomitant with turbulent flow in the dome of an aneurysm may contribute to progression and rupture. However, how stress conditions regulate enlargement of a pre-existing aneurysm remains to be elucidated. Wall shear stress was calculated with 3D-computational fluid dynamics simulation using three cases of unruptured intracranial aneurysm. The resulting value, 0.017 Pa at the dome, was much lower than that in the parent artery. We loaded wall shear stress corresponding to the value and also turbulent flow to the primary culture of endothelial cells. We then obtained gene expression profiles by RNA sequence analysis. RNA sequence analysis detected hundreds of differentially expressed genes among groups. Gene ontology and pathway analysis identified signaling related with cell division/proliferation as overrepresented in the low wall shear stress-loaded group, which was further augmented by the addition of turbulent flow. Moreover, expression of some chemoattractants for inflammatory cells, including MCP-1, was upregulated under low wall shear stress with concomitant turbulent flow. We further examined the temporal sequence of expressions of factors identified in an in vitro study using a rat model. No proliferative cells were detected, but MCP-1 expression was induced and sustained in the endothelial cell layer. Low wall shear stress concomitant with turbulent flow contributes to sustained expression of MCP-1 in endothelial cells and presumably plays a role in facilitating macrophage infiltration and exacerbating inflammation, which leads to enlargement or rupture.
Monocyte recruitment to endothelial cells in response to oscillatory shear stress

PubMed Central

Hsiai, Tzung K.; Cho, Sung K.; Wong, Pak K.; Ing, Mike; Salazar, Adler; Sevanian, Alex; Navab, Mohamad; Demer, Linda L.; Ho, Chih-Ming

2014-01-01

Leukocyte recruitment to endothelial cells is a critical event in inflammatory responses. The spatial, temporal gradients of shear stress, topology, and outcome of cellular interactions that underlie these responses have so far been inferred from static imaging of tissue sections or studies of statically cultured cells. In this report, we developed micro-electromechanical systems (MEMS) sensors, comparable to a single endothelial cell (EC) in size, to link real-time shear stress with monocyte/EC binding kinetics in a complex flow environment, simulating the moving and unsteady separation point at the arterial bifurcation with high spatial and temporal resolution. In response to oscillatory shear stress (τ) at ± 2.6 dyn/cm2 at a time-averaged shear stress (τave) = 0 and 0.5 Hz, individual monocytes displayed unique to-and-fro trajectories undergoing rolling, binding, and dissociation with other monocyte, followed by solid adhesion on EC. Our study quantified individual monocyte/EC binding kinetics in terms of displacement and velocity profiles. Oscillatory flow induces up-regulation of adhesion molecules and cytokines to mediate monocyte/EC interactions over a dynamic range of shear stress ± 2.6 dyn/cm2 (P= 0.50, n= 10).—Hsiai, T. K., Cho, S. K., Wong, P. K., Ing, M., Salazar, A., Sevanian, A., Navab, M., Demer, L. L., Ho, C.-M. Monocyte recruitment to endothelial cells in response to oscillatory shear stress. FASEB J. 17, 1648–1657 (2003) PMID:12958171
DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, J.K.; Yoo, M.H.

The aspect of elastic strain for a deformation twin with a pure shear strain is studied through Eshelby's inclusion theory. Beta-Sn, TiO[sub 2], and TiAl of tetragonal structures are considered. As the aspect ratio of a twin approaches zero, its elastic strain energy vanishes since the stress components coupled with the twin shear strain vanish, suggesting that the twin habit plane cannot be determined solely from the shear energy viewpoint, for any twin mode would provide a vanishingly small strain energy for a thin twin. The application of Johnson and Cahn's shape bifurcation theory predicts that the transition from amore » circular to an elliptic shape would occur when the linear dimension of a lenticular twin is only in the order of 10 nm, indicating that most twins with a substantial aspect ratio should be influenced by growth kinetics. Under an applied stress. The extreme condition of the free energy change usually occurs when the resolved shear stress becomes extreme in the direction of the twin shear strain, thus following the relationship of Schmid's law. The analysis of the matrix stress field immediately outside a twin plate shows a biomodal stress distribution around the lateral tip of the lenticular plate. The locations of stress concentrations depend on both the twin aspect ratio and the elastic anisotropy. The locations of stress concentrations depend on both the twin aspect ratio and the elastic anisotropy. As the twin aspect ratio approaches zero, however, the two exterior stress concentrations merge together at the lateral tip of the lenticular plate, yielding a maximum stress value in the order of [mu]g, where [mu] and g are shear modulus and twin shear strain, respectively.« less
Protein kinase B/Akt activates c-Jun NH(2)-terminal kinase by increasing NO production in response to shear stress

NASA Technical Reports Server (NTRS)

Go, Y. M.; Boo, Y. C.; Park, H.; Maland, M. C.; Patel, R.; Pritchard, K. A. Jr; Fujio, Y.; Walsh, K.; Darley-Usmar, V.; Jo, H.

2001-01-01

Laminar shear stress activates c-Jun NH(2)-terminal kinase (JNK) by the mechanisms involving both nitric oxide (NO) and phosphatidylinositide 3-kinase (PI3K). Because protein kinase B (Akt), a downstream effector of PI3K, has been shown to phosphorylate and activate endothelial NO synthase, we hypothesized that Akt regulates shear-dependent activation of JNK by stimulating NO production. Here, we examined the role of Akt in shear-dependent NO production and JNK activation by expressing a dominant negative Akt mutant (Akt(AA)) and a constitutively active mutant (Akt(Myr)) in bovine aortic endothelial cells (BAEC). As expected, pretreatment of BAEC with the PI3K inhibitor (wortmannin) prevented shear-dependent stimulation of Akt and NO production. Transient expression of Akt(AA) in BAEC by using a recombinant adenoviral construct inhibited the shear-dependent stimulation of NO production and JNK activation. However, transient expression of Akt(Myr) by using a recombinant adenoviral construct did not induce JNK activation. This is consistent with our previous finding that NO is required, but not sufficient on its own, to activate JNK in response to shear stress. These results and our previous findings strongly suggest that shear stress triggers activation of PI3K, Akt, and endothelial NO synthase, leading to production of NO, which (along with O(2-), which is also produced by shear) activates Ras-JNK pathway. The regulation of Akt, NO, and JNK by shear stress is likely to play a critical role in its antiatherogenic effects.
Incremental viscosity by non-equilibrium molecular dynamics and the Eyring model

NASA Astrophysics Data System (ADS)

Heyes, D. M.; Dini, D.; Smith, E. R.

2018-05-01

The viscoelastic behavior of sheared fluids is calculated by Non-Equilibrium Molecular Dynamics (NEMD) simulation, and complementary analytic solutions of a time-dependent extension of Eyring's model (EM) for shear thinning are derived. It is argued that an "incremental viscosity," ηi, or IV which is the derivative of the steady state stress with respect to the shear rate is a better measure of the physical state of the system than the conventional definition of the shear rate dependent viscosity (i.e., the shear stress divided by the strain rate). The stress relaxation function, Ci(t), associated with ηi is consistent with Boltzmann's superposition principle and is computed by NEMD and the EM. The IV of the Eyring model is shown to be a special case of the Carreau formula for shear thinning. An analytic solution for the transient time correlation function for the EM is derived. An extension of the EM to allow for significant local shear stress fluctuations on a molecular level, represented by a gaussian distribution, is shown to have the same analytic form as the original EM but with the EM stress replaced by its time and spatial average. Even at high shear rates and on small scales, the probability distribution function is almost gaussian (apart from in the wings) with the peak shifted by the shear. The Eyring formula approximately satisfies the Fluctuation Theorem, which may in part explain its success in representing the shear thinning curves of a wide range of different types of chemical systems.
Optimization of hydraulic shear parameters and reactor configuration in the aerobic granular sludge process.

PubMed

Zhu, Liang; Zhou, Jiaheng; Yu, Haitian; Xu, Xiangyang

2015-01-01

The hydraulic shear acts as an important selection pressure in aerobic sludge granulation. The effects of the hydraulic shear rate and reactor configuration on structural characteristics of aerobic granule in view of the hydromechanics. The hydraulic shear analysis was proposed to overcome the limitation of using superficial gas velocity (SGV) to express the hydraulic shear stress. Results showed that the stronger hydraulic shear stress with SGV above 2.4 cm s(-1) promoted the microbial aggregation, and favoured the structural stability of the granular sludge. According to the hydraulic shear analysis, the total shear rate reached (0.56-2.31)×10(5) s(-1) in the granular reactor with a larger ratio of height to diameter (H/D), and was higher than that in the reactor with smaller H/D, where the sequencing airlift bioreactor with smaller H/D had a high total shear rate under the same SGV. Results demonstrated that the granular reactor could provide a stronger hydraulic shear stress which promotes the formation and structural stability of aerobic granules.
Purinergic signaling is required for fluid shear stress-induced NF-{kappa}B translocation in osteoblasts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Genetos, Damian C., E-mail: dgenetos@ucdavis.edu; Karin, Norman J.; Geist, Derik J.

2011-04-01

Fluid shear stress regulates gene expression in osteoblasts, in part by activation of the transcription factor NF-{kappa}B. We examined whether this process was under the control of purinoceptor activation. MC3T3-E1 osteoblasts under static conditions expressed the NF-{kappa}B inhibitory protein I{kappa}B{alpha} and exhibited cytosolic localization of NF-{kappa}B. Under fluid shear stress, I{kappa}B{alpha} levels decreased, and concomitant nuclear localization of NF-{kappa}B was observed. Cells exposed to fluid shear stress in ATP-depleted medium exhibited no significant reduction in I{kappa}B{alpha}, and NF-{kappa}B remained within the cytosol. Similar results were found using oxidized ATP or Brilliant Blue G, P2X{sub 7} receptor antagonists, indicating that themore » P2X{sub 7} receptor is responsible for fluid shear-stress-induced I{kappa}B{alpha} degradation and nuclear accumulation of NF-{kappa}B. Pharmacologic blockage of the P2Y6 receptor also prevented shear-induced I{kappa}B{alpha} degradation. These phenomena involved neither ERK1/2 signaling nor autocrine activation by P2X{sub 7}-generated lysophosphatidic acid. Our results suggest that fluid shear stress regulates NF-{kappa}B activity through the P2Y{sub 6} and P2X{sub 7} receptor.« less
Crack problems for bonded nonhomogeneous materials under antiplane shear loading

NASA Technical Reports Server (NTRS)

Erdogan, F.

1984-01-01

The singular nature of the crack tip stress field in a nonhomogeneous medium with a shear modulus with a discontinuous derivative was investigated. The simplest possible loading and geometry, the antiplane shear loading of two bonded half spaces in which the crack is perpendicular to the interface is considered. It is shown that the square root singularity of the crack tip stress field is unaffected by the discontinuity in the derivative of the shear modulus. The problem is solved for a finite crack and results for the stress intensity factors are presented.
Measurement of surface shear stress vector beneath high-speed jet flow using liquid crystal coating

NASA Astrophysics Data System (ADS)

Wang, Cheng-Peng; Zhao, Ji-Song; Jiao, Yun; Cheng, Ke-Ming

2018-05-01

The shear-sensitive liquid crystal coating (SSLCC) technique is investigated in the high-speed jet flow of a micro-wind-tunnel. An approach to measure surface shear stress vector distribution using the SSLCC technique is established, where six synchronous cameras are used to record the coating color at different circumferential view angles. Spatial wall shear stress vector distributions on the test surface are obtained at different velocities. The results are encouraging and demonstrate the great potential of the SSLCC technique in high-speed wind-tunnel measurement.
Direct measurements of local bed shear stress in the presence of pressure gradients

NASA Astrophysics Data System (ADS)

Pujara, Nimish; Liu, Philip L.-F.

2014-07-01

This paper describes the development of a shear plate sensor capable of directly measuring the local mean bed shear stress in small-scale and large-scale laboratory flumes. The sensor is capable of measuring bed shear stress in the range 200 Pa with an accuracy up to 1 %. Its size, 43 mm in the flow direction, is designed to be small enough to give spatially local measurements, and its bandwidth, 75 Hz, is high enough to resolve time-varying forcing. Typically, shear plate sensors are restricted to use in zero pressure gradient flows because secondary forces on the edge of the shear plate caused by pressure gradients can introduce large errors. However, by analysis of the pressure distribution at the edges of the shear plate in mild pressure gradients, we introduce a new methodology for correcting for the pressure gradient force. The developed sensor includes pressure tappings to measure the pressure gradient in the flow, and the methodology for correction is applied to obtain accurate measurements of bed shear stress under solitary waves in a small-scale wave flume. The sensor is also validated by measurements in a turbulent flat plate boundary layer in open channel flow.
Preliminary investigation of steel girder end panel shear resistance.

DOT National Transportation Integrated Search

2010-01-01

Prior to 1973, steel bridges in California were designed based on Allowable Stress : Design and the shear design of web and transverse stiffeners was based on the : average shear stress in the web. The tension field action equation similar to the : c...
Rac1 and Cdc42 GTPases regulate shear stress-driven β-catenin signaling in osteoblasts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wan, Qiaoqiao; Cho, Eunhye; Yokota, Hiroki

2013-04-19

Highlights: •Shear stress increased TCF/LEF activity and stimulated β-catenin nuclear localization. •Rac1, Cdc42, and RhoA displayed distinct dynamic activity patterns under flow. •Rac1 and Cdc42, but not RhoA, regulate shear stress-driven TCF/LEF activation. •Cytoskeleton did not significantly affect shear stress-induced TCF/LEF activation. -- Abstract: Beta-catenin-dependent TCF/LEF (T-cell factor/lymphocyte enhancing factor) is known to be mechanosensitive and an important regulator for promoting bone formation. However, the functional connection between TCF/LEF activity and Rho family GTPases is not well understood in osteoblasts. Herein we investigated the molecular mechanisms underlying oscillatory shear stress-induced TCF/LEF activity in MC3T3-E1 osteoblast cells using live cell imaging.more » We employed fluorescence resonance energy transfer (FRET)-based and green fluorescent protein (GFP)-based biosensors, which allowed us to monitor signal transduction in living cells in real time. Oscillatory (1 Hz) shear stress (10 dynes/cm{sup 2}) increased TCF/LEF activity and stimulated translocation of β-catenin to the nucleus with the distinct activity patterns of Rac1 and Cdc42. The shear stress-induced TCF/LEF activity was blocked by the inhibition of Rac1 and Cdc42 with their dominant negative mutants or selective drugs, but not by a dominant negative mutant of RhoA. In contrast, constitutively active Rac1 and Cdc42 mutants caused a significant enhancement of TCF/LEF activity. Moreover, activation of Rac1 and Cdc42 increased the basal level of TCF/LEF activity, while their inhibition decreased the basal level. Interestingly, disruption of cytoskeletal structures or inhibition of myosin activity did not significantly affect shear stress-induced TCF/LEF activity. Although Rac1 is reported to be involved in β-catenin in cancer cells, the involvement of Cdc42 in β-catenin signaling in osteoblasts has not been identified. Our findings in this study demonstrate that both Rac1 and Cdc42 GTPases are critical regulators in shear stress-driven β-catenin signaling in osteoblasts.« less
Shear-strain energy rate distribution caused by the interplate locking along the Nankai Trough, southwest Japan: An integration analysis using stress tensor inversion and slip deficit inversion

NASA Astrophysics Data System (ADS)

Saito, T.; Noda, A.; Yoshida, K.; Tanaka, S.

2017-12-01

In the Nankai Trough, southwest Japan, the Philippine Sea Plate descends beneath the Eurasian plate. The locking, or the slip deficit, on the plate interface causes stress fluctuation in the inland area. The interplate locking does not always result in stress accumulation but also causes stress release. The stress increase/decrease is not determined only from the stress fluctuation but also depends on the background stress, in particular, its orientation. This study proposes a method to estimate the shear-strain energy increase/decrease distribution caused by the interplate locking. We at first investigated the background stress field in and around the Nankai Trough. The spatial distribution of the principal stress orientations and the stress ratio were estimated by analysis of 130,000 focal mechanisms of small earthquakes (e.g., Yoshida et al. 2015 Tectonophysics). For example, in an area called Chugoku region, the maximum and minimum compression axes were E-W and N-S directions, respectively. We also estimated the slip-deficit rate at the plate interface by analyzing GNSS data and calculated the stress fluctuation due to the deficit (e.g., Noda et al. 2013 GJI). The interplate locking causes the maximum compression in the direction of plate convergence. This is significantly different from the orientations of the background stress characterized by the E-W compressional strike-slip stress regime.. By combining the results of the background stress and the stress fluctuation, we made a map indicating the shear-strain energy change due to the interplate locking. In the Chugoku region, the shear-strain energy decreases due to the interplate locking. This is because the N-S compressional stress caused by the interplate locking compensates the N-S extensional stress in the background. The shear-strain energy increases in some parts of the analyzed areas. By statistically comparing the shear strain energy rate with the seismicity in the inland area, we found that the seismicity tends to be high where the interplate locking increases the shear-strain energy. Our results suggest that the stress fluctuation due to the interplate locking is not dominant in the background stress but surely contributes to the inland seismicity in southwest Japan.
Effect of friction on shear jamming

NASA Astrophysics Data System (ADS)

Wang, Dong; Ren, Jie; Dijksman, Joshua; Behringer, Robert

2014-03-01

Shear Jamming of granular materials was first found for systems of frictional disks, with a static friction coefficients μs ~= 0 . 6 . Jamming by shear is obtained by starting from a zero-stress state with a packing fraction ϕS <= ϕ <=ϕJ between ϕJ (isotropic jamming) and a lowest ϕS for shear jamming. This phenomenon is associated with strong anisotropy in stress and the contact network in the form of ``force chains,'' which are stabilized and/or enhanced by the presence of friction. We address experimentally how reducing friction affects shear jamming by using either teflon disks of teflon wrapped photoelastic particles. The teflon disks were placed in a wall driven 2D shear apparatus, in which we can probe shear stresses mechanically. Teflon-wrapped disks were placed in a bottom driven 2D shear apparatus (Ren et al., PRL 2013). Both apparatuses provide uniform simple shear. In all low- μ experiments, the shear jamming occurred, as observed through stress increases on the packing. However, the low- μ differences observed for ϕJ -ϕS were smaller than for higher friction particles. Ongoing work is studying systems using hydrogel disks, which have a lower friction coefficient than teflon. We acknowledge support from NSF Grant No. DMR12-06351, ARO Grant No. W911NF-1-11-0110, and NASA Grant No. NNX10AU01G.
Cyclic axial-torsional deformation behavior of a cobalt-base superalloy

NASA Technical Reports Server (NTRS)

Bonacuse, Peter J.; Kalluri, Sreeramesh

1992-01-01

Multiaxial loading, especially at elevated temperature, can cause the inelastic response of a material to differ significantly from that predicted by simple flow rules, i.e., von Mises or Tresca. To quantify some of these differences, the cyclic high-temperature, deformation behavior of a wrought cobalt-based superalloy, Haynes 188, is investigated under combined axial and torsional loads. Haynes 188 is currently used in many aerospace gas turbine and rocket engine applications, e.g., the combustor liner for the T800 turboshaft engine for the RAH-66 Comanche helicopter and the liquid oxygen posts in the main injector of the space shuttle main engine. The deformation behavior of this material is assessed through the examination of hysteresis loops generated from a biaxial fatigue test program. A high-temperature axial, torsional, and combined axial-torsional fatigue data base has been generated on Haynes 188 at 760 C. Cyclic loading tests have been conducted on uniform gauge section tubular specimens in a servohydraulic axial-torsional test rig. Test control and data acquisition were accomplished with a minicomputer. In this paper, the cyclic hardening characteristics and typical hysteresis loops in the axial stress versus axial strain, shear stress versus engineering shear strain, axial strain versus engineering shear strain, and axial stress versus shear stress spaces are presented for cyclic, in-phase and out-of-phase, axial torsional tests. For in-phase tests three different values of the proportionality constant, lambda (ratio of engineering shear strain amplitude to axial strain amplitude), are examined, viz., 0.86, 1.73, and 3.46. In the out-of-phase tests, three different values of the phase angle, phi (between the axial and engineering shear strain waveforms), are studied, viz., 30, 60, and 90 deg with lambda = 1.73. The cyclic hardening behaviors of all the tests conducted on Haynes 188 at 760 C are evaluated using the von Mises equivalent stress-strain and the maximum shear stress-maximum engineering shear strain (Tresca) curves. Comparisons are also made between the hardening behaviors of cyclic axial, torsional, and combined in-phase and out-of-phase axial-torsional fatigue tests. These comparisons are accomplished through simple Ramberg-Osgood type stress-strain functions for cyclic, axial stress-strain and shear stress-engineering shear strain curves.
The response of dense dry granular material to the shear reversal

NASA Astrophysics Data System (ADS)

Zhang, Jie; Ren, Jie; Farhadi, Somayeh; Behringer, Robert

2008-11-01

We have performed two dimensional granular experiments under pure shear using bidisperse photo-elastic disks. Starting from a stress free state, a square box filled with granular particles is subject to shear. The forward shears involved various number of steps, leading to maximum strains between 0.1 and 0.3. The area is kept constant during the shear. The network of force chains gradually built up as the strain increased, leading to increased pressure and shear stress. Reverse shear was then applied to the system. Depending on the initial packing fraction and the strain at which the shear is reversed, the force chain network built prior to the shear reversal may be destroyed completely or partially destroyed. Following the force chain weakening, when the reserve shear is continuously applied to the system, there is a force chain strengthening. Following each change of the system, contact forces of individual disks were measured by applying an inverse algorithm. We also kept track of the displacement and angle of rotation of every particle from frame to frame. We present the results for the structure failure and reconstruction during shear reversals. We also present data for stresses, contact force distributions and other statistical measures.
Rheometry of natural sediment slurries

USGS Publications Warehouse

Major, Jon J.; ,

1993-01-01

Recent experimental analyses of natural sediment slurries yield diverse results yet exhibit broad commonality of rheological responses under a range of conditions and shear rates. Results show that the relation between shear stress and shear rate is primarily nonlinear, that the relation can display marked hysteresis, that minimum shear stress can occur following yield, that physical properties of slurries are extremely sensitive to sediment concentration, and the concept of slurry yield strength is still debated. New rheometric analyses have probed viscoelastic behavior of sediment slurries. Results show that slurries composed of particles ??? 125 ?? m exhibit viscoelastic responses, and that shear stresses are relaxed over a range of time scales rather than by a single response time.
Shear-stress fluctuations and relaxation in polymer glasses

NASA Astrophysics Data System (ADS)

Kriuchevskyi, I.; Wittmer, J. P.; Meyer, H.; Benzerara, O.; Baschnagel, J.

2018-01-01

We investigate by means of molecular dynamics simulation a coarse-grained polymer glass model focusing on (quasistatic and dynamical) shear-stress fluctuations as a function of temperature T and sampling time Δ t . The linear response is characterized using (ensemble-averaged) expectation values of the contributions (time averaged for each shear plane) to the stress-fluctuation relation μsf for the shear modulus and the shear-stress relaxation modulus G (t ) . Using 100 independent configurations, we pay attention to the respective standard deviations. While the ensemble-averaged modulus μsf(T ) decreases continuously with increasing T for all Δ t sampled, its standard deviation δ μsf(T ) is nonmonotonic with a striking peak at the glass transition. The question of whether the shear modulus is continuous or has a jump singularity at the glass transition is thus ill posed. Confirming the effective time-translational invariance of our systems, the Δ t dependence of μsf and related quantities can be understood using a weighted integral over G (t ) .
Evaluation of shear-compressive strength properties for laminated GFRP composites in electromagnet system

NASA Astrophysics Data System (ADS)

Song, Jun Hee; Kim, Hak Kun; Kim, Sam Yeon

2014-07-01

Laminated fiber-reinforced composites can be applied to an insulating structure of a nuclear fusion device. It is necessary to investigate the interlaminar fracture characteristics of the laminated composites for the assurance of design and structural integrity. The three methods used to prepare the glass fiber reinforced plastic composites tested in this study were vacuum pressure impregnation, high pressure laminate (HPL), and prepreg laminate. We discuss the design criteria for safe application of composites and the shear-compressive test methods for evaluating mechanical properties of the material. Shear-compressive tests could be performed successfully using series-type test jigs that were inclined 0°, 30°, 45°, 60°, and 75° to the normal axis. Shear strength depends strongly on the applied compressive stress. The design range of allowable shear stress was extended by use of the appropriate composite fabrication method. HPL had the largest design range, and the allowable interlaminar shear stress was 0.254 times the compressive stress.
Resolved shear stress intensity coefficient and fatigue crack growth in large crystals

NASA Technical Reports Server (NTRS)

Chen, Q.; Liu, H. W.

1988-01-01

Fatigue crack growth tests were carried out on large-grain Al 7029 aluminum alloy and the finite element method was used to calculate the stress field near the tip of a zigzag crack. The resolved shear stresses on all 12 slip systems were computed, and the resolved shear stress intensity coefficient (RSSIC) was defined. The RSSIC was used to analyze the irregular crack path and was correlated with the rate of single-slip-plane shear crack growth. Fatigue crack growth was found to be caused primarily by shear decohesion at a crack tip. When the RSSIC on a single-slip system was much larger than all the others, the crack followed a single-slip plane. When the RSSICs on two conjugate slip systems were comparable, a crack grew in a zigzag manner on these planes and the macrocrack-plane bisected the two active slip planes. The maximum RSSIC on the most active slip system is proposed as a parameter to correlate with the shear fatigue crack growth rate in large crystals.

A micro-kinematic framework for vorticity analysis in polyphase shear zones using integrated field, microstructural and crystallographic orientation-dispersion methods

NASA Astrophysics Data System (ADS)

Kruckenberg, S. C.; Michels, Z. D.; Parsons, M. M.

2017-12-01

We present results from integrated field, microstructural and textural analysis in the Burlington mylonite zone (BMZ) of eastern Massachusetts to establish a unified micro-kinematic framework for vorticity analysis in polyphase shear zones. Specifically, we define the vorticity-normal surface based on lattice-scale rotation axes calculated from electron backscatter diffraction data using orientation statistics. In doing so, we objectively identify a suitable reference frame for rigid grain methods of vorticity analysis that can be used in concert with textural studies to constrain field- to plate-scale deformation geometries without assumptions that may bias tectonic interpretations, such as relationships between kinematic axes and fabric forming elements or the nature of the deforming zone (e.g., monoclinic vs. triclinic shear zones). Rocks within the BMZ comprise a heterogeneous mix of quartzofeldspathic ± hornblende-bearing mylonitic gneisses and quartzites. Vorticity axes inferred from lattice rotations lie within the plane of mylonitic foliation perpendicular to lineation - a pattern consistent with monoclinic deformation geometries involving simple shear and/or wrench-dominated transpression. The kinematic vorticity number (Wk) is calculated using Rigid Grain Net analysis and ranges from 0.25-0.55, indicating dominant general shear. Using the calculated Wk values and the dominant geographic fabric orientation, we constrain the angle of paleotectonic convergence between the Nashoba and Avalon terranes to 56-75º with the convergence vector trending 142-160° and plunging 3-10°. Application of the quartz recrystallized grain size piezometer suggests differential stresses in the BMZ mylonites ranging from 44 to 92 MPa; quartz CPO patterns are consistent with deformation at greenschist- to amphibolite-facies conditions. We conclude that crustal strain localization in the BMZ involved a combination of pure and simple shear in a sinistral reverse transpressional shear zone formed at or near the brittle-ductile transition under relatively high stress conditions. Moreover, we demonstrate the utility of combined crystallographic and rigid grain methods of vorticity analysis for deducing deformation geometries, kinematics, and tectonic histories in polyphase shear zones.
The shear band controlled deformation in metallic glass: a perspective from fracture

NASA Astrophysics Data System (ADS)

Yang, G. N.; Shao, Y.; Yao, K. F.

2016-02-01

Different from the homogenous deformation in conventional crystalline alloys, metallic glasses and other work-softening materials deform discontinuously by localized plastic strain in shear bands. Here by three-point bending test on a typical ductile Pd-Cu-Si metallic glass, we found that the plastic deformed region during fracture didn’t follow the yielding stress distribution as the conventional material mechanics expected. We speculated that such special behavior was because the shear bands in metallic glasses could propagate easily along local shear stress direction once nucleated. Based on a 3D notch tip stress field simulation, we considered a new fracture process in a framework of multiple shear band deformation mechanism instead of conventional materials mechanics, and successfully reproduced the as-observed complicate shear band morphologies. This work clarifies many common misunderstandings on metallic glasses fracture, and might also provide a new insight to the shear band controlled deformation. It suggests that the deformation of metallic glasses is sensitive to local stress condition, and therefore their mechanical properties would depend on not only the material, but also other external factors on stress condition. We hope that start from this work, new methods, criteria, or definitions could be proposed to further study these work-softening materials, especially for metallic glasses.
Origins of the anomalous stress behavior in charged colloidal suspensions under shear.

PubMed

Kumar, Amit; Higdon, Jonathan J L

2010-11-01

Numerical simulations are conducted to determine microstructure and rheology of sheared suspensions of charged colloidal particles at a volume fraction of ϕ=0.33. Over broad ranges of repulsive force strength F0 and Péclet number Pe, dynamic simulations show coexistence of ordered and disordered stable states with the state dependent on the initial condition. In contrast to the common view, at low shear rates, the disordered phase exhibits a lower viscosity (μ(r)) than the ordered phase, while this behavior is reversed at higher shear rates. Analysis shows the stress reversal is associated with different shear induced microstructural distortions in the ordered and disordered systems. Viscosity vs shear rate data over a wide range of F0 and Pe collapses well upon rescaling with the long-time self-diffusivity. Shear thinning viscosity in the ordered phase scaled as μ(r)∼Pe(-0.81) at low shear rates. The microstructural dynamics revealed in these studies explains the anomalous behavior and hysteresis loops in stress data reported in the literature.
Unraveling the Role of Order-to-Disorder Transition in Shear Thickening Suspensions

NASA Astrophysics Data System (ADS)

Lee, Jonghun; Jiang, Zhang; Wang, Jin; Sandy, Alec R.; Narayanan, Suresh; Lin, Xiao-Min

2018-01-01

Using high-resolution in situ small angle x-ray scattering in conjunction with oscillatory shear on highly monodisperse silica suspensions, we demonstrate that an order-to-disorder transition leads to a dynamic shear thickening in a lower stress regime than the standard steady shear thickening. We show that the order-to-disorder transition is controlled by strain, which is distinguishably different from steady shear thickening, which is a stress-related phenomenon. The appearance of this two-step shear thinning and thickening transition is also influenced by the particle size, monodispersity, and measurement conditions (i.e., oscillatory shear versus steady shear). Our results show definitively that the order-to-disorder transition-induced thickening is completely unrelated to the mechanism that drives steady shear thickening.
Characterization of crack growth under combined loading

NASA Technical Reports Server (NTRS)

Feldman, A.; Smith, F. W.; Holston, A., Jr.

1977-01-01

Room-temperature static and cyclic tests were made on 21 aluminum plates in the shape of a 91.4x91.4-cm Maltese cross with 45 deg flaws to develop crack growth and fracture toughness data under mixed-mode conditions. During cyclic testing, it was impossible to maintain a high proportion of shear-mode deformation on the crack tips. Cracks either branched or turned. Under static loading, cracks remained straight if shear stress intensity exceeded normal stress intensity. Mixed-mode crack growth rate data compared reasonably well with published single-mode data, and measured crack displacements agreed with the straight and branched crack analyses. Values of critical strain energy release rate at fracture for pure shear were approximately 50% higher than for pure normal opening, and there was a large reduction in normal stress intensity at fracture in the presence of high shear stress intensity. Net section stresses were well into the inelastic range when fracture occurred under high shear on the cracks.
Evaluation of bed load transport subject to high shear stress fluctuations

NASA Astrophysics Data System (ADS)

Cheng, Nian-Sheng; Tang, Hongwu; Zhu, Lijun

2004-05-01

Many formulas available in the literature for computing sediment transport rates are often expressed in terms of time mean variables such as time mean bed shear stress or flow velocity, while effects of turbulence intensity, e.g., bed shear stress fluctuation, on sediment transport were seldom considered. This may be due to the fact that turbulence fluctuation is relatively limited in laboratory open-channel flows, which are often used for conducting sediment transport experiments. However, turbulence intensity could be markedly enhanced in practice. This note presents an analytical method to compute bed load transport by including effects of fluctuations in the bed shear stress. The analytical results obtained show that the transport rate enhanced by turbulence can be expressed as a simple function of the relative fluctuation of the bed shear stress. The results are also verified using data that were collected recently from specifically designed laboratory experiments. The present analysis is applicable largely for the condition of a flat bed that is comprised of uniform sand particles subject to unidirectional flows.
Elevated Shear Stress in Arteriovenous Fistulae: Is There Mechanical Homeostasis?

NASA Astrophysics Data System (ADS)

McGah, Patrick; Leotta, Daniel; Beach, Kirk; Aliseda, Alberto

2011-11-01

Arteriovenous fistulae are created surgically to provide access for dialysis in patients with renal failure. The current hypothesis is that the rapid remodeling occurring after the fistula creation is in part a process to restore the mechanical stresses to some preferred level (i.e. mechanical homeostasis). Given that nearly 50% of fistulae require an intervention after one year, understanding the altered hemodynamic stress is important in improving clinical outcomes. We perform numerical simulations of four patient-specific models of functioning fistulae reconstructed from 3D Doppler ultrasound scans. Our results show that the vessels are subjected to `normal' shear stresses away from the anastomosis; about 1 Pa in the veins and about 2.5 Pa in the arteries. However, simulations show that part of the anastomoses are consistently subjected to very high shear stress (>10Pa) over the cardiac cycle. These elevated values shear stresses are caused by the transitional flows at the anastomoses including flow separation and quasiperiodic vortex shedding. This suggests that the remodeling process lowers shear stress in the fistula but that it is limited as evidenced by the elevated shear at the anastomoses. This constant insult on the arterialized venous wall may explain the process of late fistula failure in which the dialysis access become occluded after years of use. Supported by an R21 Grant from NIDDK (DK081823).
Interlaminar shear stress effects on the postbuckling response of graphite-epoxy panels

NASA Technical Reports Server (NTRS)

Engelstad, S. P.; Knight, N. F., Jr.; Reddy, J. N.

1990-01-01

The influence of shear flexibility on overall postbuckling response was assessed, and transverse shear stress distributions in relation to panel failure were examined. Nonlinear postbuckling results are obtained for finite element models based on classical laminated plate theory and first-order shear deformation theory. Good correlation between test and analysis is obtained. The results presented analytically substantiate the experimentally observed failure mode.
Re-Evaluation of the Lower San Fernando Dam. Report 2. Examination of the Post-Earthquake Slide of February 9, 1971

DTIC Science & Technology

1989-09-01

the initial shear driving shear stress stress Initial {Failure occurs when strength drops below the initial shear idriving shear stressstress Steady...back pressure saturation (to a "B-value" o iot less than B = 0.98) most of the samples were isotropically co:,solidated to 0𔃽, i = 2.0 ksc. Some of the
Bonded joint and method. [for reducing peak shear stress in adhesive bonds

NASA Technical Reports Server (NTRS)

Sainsbury-Carter, J. B. (Inventor)

1974-01-01

An improved joint is described for reducing the peak shear stress in adhesive bonds when adhesives are used to bond two materials which are in a lapped relationship and which differ in value of modulus of elasticity. An insert placed between the adhesive and one of the two materials acts to cushion the discontinuity of material stiffness thereby reducing the peak shear stress in the adhesive bond.
Role of hemolysis in red cell adenosine triphosphate release in simulated exercise conditions in vitro.

PubMed

Mairbäurl, Heimo; Ruppe, Florian A; Bärtsch, Peter

2013-10-01

Specific adenosine triphosphate (ATP) release from red blood cells has been discussed as a possible mediator controlling microcirculation in states of decreased tissue oxygen. Because intravascular hemolysis might also contribute to plasma ATP, we tested in vitro which portion of ATP release is due to hemolysis in typical exercise-induced strains to the red blood cells (shear stress, deoxygenation, and lactic acidosis). Human erythrocytes were suspended in dextran-containing media (hematocrit 10%) and were exposed to shear stress in a rotating Couette viscometer at 37°C. Desaturation (oxygen saturation of hemoglobin ∼20%) was achieved by tonometry with N2 before shear stress exposure. Cells not exposed to shear stress were used as controls. Na lactate (15 mM), lactic acid (15 mM, pH 7.0), and HCl (pH 7.0) were added to simulate exercise-induced lactic acidosis. After incubation, extracellular hemoglobin was measured to quantify hemolysis. ATP was measured with the luciferase assay. Shear stress increased extracellular ATP in a stress-related and time-dependent manner. Hypoxia induced a ∼10-fold increase in extracellular ATP in nonsheared cells and shear stress-exposed cells. Lactic acid had no significant effect on ATP release and hemolysis. In normoxic cells, approximately 20%-50% of extracellular ATP was due to hemolysis. This proportion decreased to less than 10% in hypoxic cells. Our results indicate that when exposing red blood cells to typical strains they encounter when passing through capillaries of exercising skeletal muscle, ATP release from red blood cells is caused mainly by deoxygenation and shear stress, whereas lactic acidosis had only a minor effect. Hemolysis effects were decreased when hemoglobin was deoxygenated. Together, by specific release and hemolysis, extracellular ATP reaches values that have been shown to cause local vasodilatation.
Determination of wall shear stress from mean velocity and Reynolds shear stress profiles

NASA Astrophysics Data System (ADS)

Volino, Ralph J.; Schultz, Michael P.

2018-03-01

An analytical method is presented for determining the Reynolds shear stress profile in steady, two-dimensional wall-bounded flows using the mean streamwise velocity. The method is then utilized with experimental data to determine the local wall shear stress. The procedure is applicable to flows on smooth and rough surfaces with arbitrary pressure gradients. It is based on the streamwise component of the boundary layer momentum equation, which is transformed into inner coordinates. The method requires velocity profiles from at least two streamwise locations, but the formulation of the momentum equation reduces the dependence on streamwise gradients. The method is verified through application to laminar flow solutions and turbulent DNS results from both zero and nonzero pressure gradient boundary layers. With strong favorable pressure gradients, the method is shown to be accurate for finding the wall shear stress in cases where the Clauser fit technique loses accuracy. The method is then applied to experimental data from the literature from zero pressure gradient studies on smooth and rough walls, and favorable and adverse pressure gradient cases on smooth walls. Data from very near the wall are not required for determination of the wall shear stress. Wall friction velocities obtained using the present method agree with those determined in the original studies, typically to within 2%.
Large scale structures in a turbulent boundary layer and their imprint on wall shear stress

NASA Astrophysics Data System (ADS)

Pabon, Rommel; Barnard, Casey; Ukeiley, Lawrence; Sheplak, Mark

2015-11-01

Experiments were performed on a turbulent boundary layer developing on a flat plate model under zero pressure gradient flow. A MEMS differential capacitive shear stress sensor with a 1 mm × 1 mm floating element was used to capture the fluctuating wall shear stress simultaneously with streamwise velocity measurements from a hot-wire anemometer traversed in the wall normal direction. Near the wall, the peak in the cross correlation corresponds to an organized motion inclined 45° from the wall. In the outer region, the peak diminishes in value, but is still significant at a distance greater than half the boundary layer thickness, and corresponds to a structure inclined 14° from the wall. High coherence between the two signals was found for the low-frequency content, reinforcing the belief that large scale structures have a vital impact on wall shear stress. Thus, estimation of the wall shear stress from the low-frequency velocity signal will be performed, and is expected to be statistically significant in the outer boundary layer. Additionally, conditionally averaged mean velocity profiles will be presented to assess the effects of high and low shear stress. This material is based upon work supported by the National Science Foundation Graduate Research Fellowship under Grant No. DGE-1315138.
In situ monitoring of localized shear stress and fluid flow within developing tissue constructs by Doppler optical coherence tomography

NASA Astrophysics Data System (ADS)

Jia, Yali; Bagnaninchi, Pierre O.; Wang, Ruikang K.

2008-02-01

Mechanical stimuli can be introduced to three dimensional (3D) cell cultures by use of perfusion bioreactor. Especially in musculoskeletal tissues, shear stress caused by fluid flow generally increase extra-cellular matrix (ECM) production and cell proliferation. The relationship between the shear stress and the tissue development in situ is complicated because of the non-uniform pore distribution within the cell-seeded scaffold. In this study, we firstly demonstrated that Doppler optical coherence tomography (DOCT) is capable of monitoring localized fluid flow and shear stress in the complex porous scaffold by examining their variation trends at perfusion rate of 5, 8, 10 and 12 ml/hr. Then, we developed the 3D porous cellular constructs, cell-seeded chitosan scaffolds monitored during several days by DOCT. The fiber based fourier domain DOCT employed a 1300 nm superluminescent diode with a bandwidth of 52 nm and a xyz resolution of 20×20×15 μm in free space. This setup allowed us not only to assess the cell growth and ECM deposition by observing their different scattering behaviors but also to further investigate how the cell attachment and ECM production has the effect on the flow shear stress and the relationship between flow rate and shear stress in the developing tissue construct. The possibility to monitor continuously the constructs under perfusion will easily indicate the effect of flow rate or shear stress on the cell viability and cell proliferation, and then discriminate the perfusion parameters affecting the pre-tissue formation rate growth.
Normalization of flow-mediated dilation to shear stress area under the curve eliminates the impact of variable hyperemic stimulus.

PubMed

Padilla, Jaume; Johnson, Blair D; Newcomer, Sean C; Wilhite, Daniel P; Mickleborough, Timothy D; Fly, Alyce D; Mather, Kieren J; Wallace, Janet P

2008-09-04

Normalization of brachial artery flow-mediated dilation (FMD) to individual shear stress area under the curve (peak FMD:SSAUC ratio) has recently been proposed as an approach to control for the large inter-subject variability in reactive hyperemia-induced shear stress; however, the adoption of this approach among researchers has been slow. The present study was designed to further examine the efficacy of FMD normalization to shear stress in reducing measurement variability. Five different magnitudes of reactive hyperemia-induced shear stress were applied to 20 healthy, physically active young adults (25.3 +/- 0. 6 yrs; 10 men, 10 women) by manipulating forearm cuff occlusion duration: 1, 2, 3, 4, and 5 min, in a randomized order. A venous blood draw was performed for determination of baseline whole blood viscosity and hematocrit. The magnitude of occlusion-induced forearm ischemia was quantified by dual-wavelength near-infrared spectrometry (NIRS). Brachial artery diameters and velocities were obtained via high-resolution ultrasound. The SSAUC was individually calculated for the duration of time-to-peak dilation. One-way repeated measures ANOVA demonstrated distinct magnitudes of occlusion-induced ischemia (volume and peak), hyperemic shear stress, and peak FMD responses (all p < 0.0001) across forearm occlusion durations. Differences in peak FMD were abolished when normalizing FMD to SSAUC (p = 0.785). Our data confirm that normalization of FMD to SSAUC eliminates the influences of variable shear stress and solidifies the utility of FMD:SSAUC ratio as an index of endothelial function.
Relating Vorticity Confinement to the Menter Shear Stress Transport Turbulence Model

DTIC Science & Technology

2008-01-01

uses a bent nose to effect aerodynamic control. The baseline geometry was constructed with CFDGEN using wind tunnel model blueprints and it...For the problem at hand, Reference 23 was used to find the boundary layer thickness at the separation point of a cylinder in cross flow and relate it...to the cylinder radius. Although it was only possible to find the thickness of a laminar boundary layer, the ratio of measured turbulent and laminar
Numerical design and optimization of hydraulic resistance and wall shear stress inside pressure-driven microfluidic networks.

PubMed

Damiri, Hazem Salim; Bardaweel, Hamzeh Khalid

2015-11-07

Microfluidic networks represent the milestone of microfluidic devices. Recent advancements in microfluidic technologies mandate complex designs where both hydraulic resistance and pressure drop across the microfluidic network are minimized, while wall shear stress is precisely mapped throughout the network. In this work, a combination of theoretical and modeling techniques is used to construct a microfluidic network that operates under minimum hydraulic resistance and minimum pressure drop while constraining wall shear stress throughout the network. The results show that in order to minimize the hydraulic resistance and pressure drop throughout the network while maintaining constant wall shear stress throughout the network, geometric and shape conditions related to the compactness and aspect ratio of the parent and daughter branches must be followed. Also, results suggest that while a "local" minimum hydraulic resistance can be achieved for a geometry with an arbitrary aspect ratio, a "global" minimum hydraulic resistance occurs only when the aspect ratio of that geometry is set to unity. Thus, it is concluded that square and equilateral triangular cross-sectional area microfluidic networks have the least resistance compared to all rectangular and isosceles triangular cross-sectional microfluidic networks, respectively. Precise control over wall shear stress through the bifurcations of the microfluidic network is demonstrated in this work. Three multi-generation microfluidic network designs are considered. In these three designs, wall shear stress in the microfluidic network is successfully kept constant, increased in the daughter-branch direction, or decreased in the daughter-branch direction, respectively. For the multi-generation microfluidic network with constant wall shear stress, the design guidelines presented in this work result in identical profiles of wall shear stresses not only within a single generation but also through all the generations of the microfluidic network under investigation. The results obtained in this work are consistent with previously reported data and suitable for a wide range of lab-on-chip applications.
Shear stress increases nitric oxide production in thick ascending limbs

PubMed Central

Cabral, Pablo D.; Hong, Nancy J.

2010-01-01

We showed that luminal flow stimulates nitric oxide (NO) production in thick ascending limbs. Ion delivery, stretch, pressure, and shear stress all increase when flow is enhanced. We hypothesized that shear stress stimulates NO in thick ascending limbs, whereas stretch, pressure, and ion delivery do not. We measured NO in isolated, perfused rat thick ascending limbs using the NO-sensitive dye DAF FM-DA. NO production rose from 21 ± 7 to 58 ± 12 AU/min (P < 0.02; n = 7) when we increased luminal flow from 0 to 20 nl/min, but dropped to 16 ± 8 AU/min (P < 0.02; n = 7) 10 min after flow was stopped. Flow did not increase NO in tubules from mice lacking NO synthase 3 (NOS 3). Flow stimulated NO production by the same extent in tubules perfused with ion-free solution and physiological saline (20 ± 7 vs. 24 ± 6 AU/min; n = 7). Increasing stretch while reducing shear stress and pressure lowered NO generation from 42 ± 9 to 17 ± 6 AU/min (P < 0.03; n = 6). In the absence of shear stress, increasing pressure and stretch had no effect on NO production (2 ± 8 vs. 8 ± 8 AU/min; n = 6). Similar results were obtained in the presence of tempol (100 μmol/l), a O2− scavenger. Primary cultures of thick ascending limb cells subjected to shear stresses of 0.02 and 0.55 dyne/cm2 produced NO at rates of 55 ± 10 and 315 ± 93 AU/s, respectively (P < 0.002; n = 7). Pretreatment with the NOS inhibitor l-NAME (5 mmol/l) blocked the shear stress-induced increase in NO production. We concluded that shear stress rather than pressure, stretch, or ion delivery mediates flow-induced stimulation of NO by NOS 3 in thick ascending limbs. PMID:20719980
Crack problems for bonded nonhomogeneous materials under antiplane shear loading

NASA Technical Reports Server (NTRS)

Erdogan, F.

1985-01-01

The singular nature of the crack tip stress field in a nonhomogeneous medium having a shear modulus with a discontinuous derivative was investigated. The problem is considered for the simplest possible loading and geometry, namely the antiplane shear loading of two bonded half spaces in which the crack is perpendicular to the interface. It is shown that the square-root singularity of the crack tip stress field is unaffected by the discontinuity in the derivative of the shear modulus. The problem is solved for a finite crack and extensive results are given for the stress intensity factors.
The crack problem for bonded nonhomogeneous materials under antiplane shear loading

NASA Technical Reports Server (NTRS)

Erdogan, F.

1985-01-01

The singular nature of the crack tip stress field in a nonhomogeneous medium having a shear modulus with a discontinuous derivative was investigated. The problem is considered for the simplest possible loading and geometry, namely the antiplane shear loading of two bonded half spaces in which the crack is perpendicular to the interface. It is shown that the square-root singularity of the crack tip stress field is unaffected by the discontinuity in the derivative of the shear modulus. The problem is solved for a finite crack and extensive results are given for the stress intensity factors.

Viscoplasticity of simulated high-level radioactive waste glass containing platinum group metal particles

NASA Astrophysics Data System (ADS)

Uruga, Kazuyoshi; Usami, Tsuyoshi; Tsukada, Takeshi; Komamine, Satoshi; Ochi, Eiji

2014-09-01

The shear rate dependency of the viscosity of three simulated high-level radioactive waste glasses containing 0, 1.2 and 4.5 wt% platinum group metals (PGMs) was examined at a temperature range of 1173-1473 K by a rotating viscometer. Shear stress when the shear rate equals zero, i.e. yield stress, was also measured by capillary method. The viscosity of the glass containing no PGM was shear rate-independent Newtonian fluid. On the other hand, the apparent viscosity of the glasses containing PGMs increased with decreasing shear rate, and nonzero amount of yield stresses were detected from both glasses. The viscosity and yield stress of the glass containing 4.5 wt% PGMs was roughly one to two orders of magnitude greater than the glass containing 1.2 wt% PGMs. These viscoplastic properties were numerically expressed by Casson equation.
Inelastic properties of ice Ih at low temperatures and high pressures

USGS Publications Warehouse

Kirby, S.H.; Durham, W.B.; Beeman, M.L.; Heard, H.C.; Daley, M.A.

1987-01-01

The aim of our research programme is to explore the rheological behavior of H2O ices under conditions appropriate to the interiors of the icy satellites of the outer planets in order to give insight into their deformation. To this end, we have performed over 100 constant-strain-rate compression tests at pressures to 500 MPa and temperatures as low as 77 K. At P > 30 MPa, ice Ih fails by a shear instability producing faults in the maximum shear stress orientation and failure strength typically is independent of pressure. This unusual faulting behavior is thought to be connected with phase transformations localized in the shear zones. The steady-state strength follows rheological laws of the thermally-activated power-law type, with different flow law parameters depending on the range of test temperatures. The flow laws will be discussed with reference to the operating deformation mechanisms as deduced from optical-scale microstructures and comparison with other work.
A Multi-Phase Based Fluid-Structure-Microfluidic interaction sensor for Aerodynamic Shear Stress

NASA Astrophysics Data System (ADS)

Hughes, Christopher; Dutta, Diganta; Bashirzadeh, Yashar; Ahmed, Kareem; Qian, Shizhi

2014-11-01

A novel innovative microfluidic shear stress sensor is developed for measuring shear stress through multi-phase fluid-structure-microfluidic interaction. The device is composed of a microfluidic cavity filled with an electrolyte liquid. Inside the cavity, two electrodes make electrochemical velocimetry measurements of the induced convection. The cavity is sealed with a flexible superhydrophobic membrane. The membrane will dynamically stretch and flex as a result of direct shear cross-flow interaction with the seal structure, forming instability wave modes and inducing fluid motion within the microfluidic cavity. The shear stress on the membrane is measured by sensing the induced convection generated by membrane deflections. The advantages of the sensor over current MEMS based shear stress sensor technology are: a simplified design with no moving parts, optimum relationship between size and sensitivity, no gaps such as those created by micromachining sensors in MEMS processes. We present the findings of a feasibility study of the proposed sensor including wind-tunnel tests, microPIV measurements, electrochemical velocimetry, and simulation data results. The study investigates the sensor in the supersonic and subsonic flow regimes. Supported by a NASA SBIR phase 1 contract.
Bending and shear stresses developed by the instantaneous arrest of the root of a cantilever beam rotating with constant angular velocity about a transverse axis through the root

NASA Technical Reports Server (NTRS)

Stowell, Elbridge Z; Schwartz, Edward B; Houbolt, John C

1945-01-01

A theoretical investigation was made of the behavior of a cantilever beam in rotational motion about a transverse axis through the root determining the stresses, the deflections, and the accelerations that occur in the beam as a result of the arrest of motion. The equations for bending and shear stress reveal that, at a given percentage of the distance from root to tip and at a given trip velocity, the bending stresses for a particular mode are independent of the length of the beam and the shear stresses vary inversely with the length. When examined with respect to a given angular velocity instead of a given tip velocity, the equations reveal that the bending stress is proportional to the length of the beam whereas the shear stress is independent of the length. Sufficient experimental verification of the theory has previously been given in connection with another problem of the same type.
The relationship between the deep-level structure in crust and brewing of strong earthquakes in Xingtai area

NASA Astrophysics Data System (ADS)

Xiao, Lan-Xi; Zhu, Yuan-Qing; Zhang, Shao-Quan; Liu, Xu; Guo, Yu

1999-11-01

In this paper, crust medium is treated as Maxwell medium, and crust model includes hard inclusion, soft inclusion, deep-level fault. The stress concentration and its evolution with time are obtained by using three-dimensional finite element method and differential method. The conclusions are draw as follows: (1) The average stress concentration and maximum shear stress concentration caused by non-heterogeneous of crust are very high in hard inclusion and around the deep fault. With the time passing by, the concentration of average stress in the model gradually trends to uniform. At the same time, the concentration of maximum shear stress in hard inclusion increases gradually. This character is favorable to transfer shear strain energy from soft inclusion to hard inclusion. (2) When the upper mantle beneath the inclusion upheave at a certain velocity of 1 cm/a, the changes of average stress concentration with time become complex, and the boundary of the hard and soft inclusion become unconspicuous, but the maximum shear stress concentration increases much more in the hard inclusion with time at a higher velocity. This feature make for transformation of energy from the soft inclusion to the hard inclusion. (3) The changes of average stress concentration and maximum shear stress concentration with time around the deep-level fault result in further accumulation of maximum shear stress concentration and finally cause the deep-level fault instable and accelerated creep along fault direction. (4) The changes of vertical displacement on the surface of the model, which is caused by the accelerated creep of the deep-level fault, is similar to that of the observation data before Xingtai strong earthquake.
Fault geometries in basement-induced wrench faulting under different initial stress states

NASA Astrophysics Data System (ADS)

Naylor, M. A.; Mandl, G.; Supesteijn, C. H. K.

Scaled sandbox experiments were used to generate models for relative ages, dip, strike and three-dimensional shape of faults in basement-controlled wrench faulting. The basic fault sequence runs from early en échelon Riedel shears and splay faults through 'lower-angle' shears to P shears. The Riedel shears are concave upwards and define a tulip structure in cross-section. In three dimensions, each Riedel shear has a helicoidal form. The sequence of faults and three-dimensional geometry are rationalized in terms of the prevailing stress field and Coulomb-Mohr theory of shear failure. The stress state in the sedimentary overburden before wrenching begins has a substantial influence on the fault geometries and on the final complexity of the fault zone. With the maximum compressive stress (∂ 1) initially parallel to the basement fault (transtension), Riedel shears are only slightly en échelon, sub-parallel to the basement fault, steeply dipping with a reduced helicoidal aspect. Conversely, with ∂ 1 initially perpendicular to the basement fault (transpression), Riedel shears are strongly oblique to the basement fault strike, have lower dips and an exaggerated helicoidal form; the final fault zone is both wide and complex. We find good agreement between the models and both mechanical theory and natural examples of wrench faulting.
A Digital Image-Based Discrete Fracture Network Model and Its Numerical Investigation of Direct Shear Tests

NASA Astrophysics Data System (ADS)

Wang, Peitao; Cai, Meifeng; Ren, Fenhua; Li, Changhong; Yang, Tianhong

2017-07-01

This paper develops a numerical approach to determine the mechanical behavior of discrete fractures network (DFN) models based on digital image processing technique and particle flow code (PFC2D). A series of direct shear tests of jointed rocks were numerically performed to study the effect of normal stress, friction coefficient and joint bond strength on the mechanical behavior of joint rock and evaluate the influence of micro-parameters on the shear properties of jointed rocks using the proposed approach. The complete shear stress-displacement curve of the DFN model under direct shear tests was presented to evaluate the failure processes of jointed rock. The results show that the peak and residual strength are sensitive to normal stress. A higher normal stress has a greater effect on the initiation and propagation of cracks. Additionally, an increase in the bond strength ratio results in an increase in the number of both shear and normal cracks. The friction coefficient was also found to have a significant influence on the shear strength and shear cracks. Increasing in the friction coefficient resulted in the decreasing in the initiation of normal cracks. The unique contribution of this paper is the proposed modeling technique to simulate the mechanical behavior of jointed rock mass based on particle mechanics approaches.
On investigating wall shear stress in two-dimensional plane turbulent wall jets

NASA Astrophysics Data System (ADS)

Mehdi, Faraz; Johansson, Gunnar; White, Christopher; Naughton, Jonathan

2012-11-01

Mehdi & White [Exp Fluids 50:43-51(2011)] presented a full momentum integral based method for determining wall shear stress in zero pressure gradient turbulent boundary layers. They utilized the boundary conditions at the wall and at the outer edge of the boundary layer. A more generalized expression is presented here that uses just one boundary condition at the wall. The method is mathematically exact and has an advantage of having no explicit streamwise gradient terms. It is successfully applied to two different experimental plane turbulent wall jet datasets for which independent estimates of wall shear stress were known. Complications owing to experimental inaccuracies in determining wall shear stress from the proposed method are also discussed.
Enhancement of human mesenchymal stem cell infiltration into the electrospun poly(lactic-co-glycolic acid) scaffold by fluid shear stress.

PubMed

Kim, Min Sung; Lee, Mi Hee; Kwon, Byeong-Ju; Koo, Min-Ah; Seon, Gyeung Mi; Park, Jong-Chul

The infiltration of the cells into the scaffolds is important phenomenon to give them good biocompatibility and even biodegradability. Fluid shear stress is one of the candidates for the infiltration of cells into scaffolds. Here we investigated the directional migration of human mesenchymal stem cells and infiltration into PLGA scaffold by fluid shear stress. The human mesenchymal stem cells showed directional migrations following the direction of the flow (8, 16 dyne/cm(2)). In the scaffold models, the fluid shear stress (8 dyne/cm(2)) enhanced the infiltration of cells but did not influence on the infiltration of Poly(lactic-co-glycolic acid) particles. Copyright © 2015 Elsevier Inc. All rights reserved.
Controlling Shear Stress in 3D Bioprinting is a Key Factor to Balance Printing Resolution and Stem Cell Integrity.

PubMed

Blaeser, Andreas; Duarte Campos, Daniela Filipa; Puster, Uta; Richtering, Walter; Stevens, Molly M; Fischer, Horst

2016-02-04

A microvalve-based bioprinting system for the manufacturing of high-resolution, multimaterial 3D-structures is reported. Applying a straightforward fluid-dynamics model, the shear stress at the nozzle site can precisely be controlled. Using this system, a broad study on how cell viability and proliferation potential are affected by different levels of shear stress is conducted. Complex, multimaterial 3D structures are printed with high resolution. This work pioneers the investigation of shear stress-induced cell damage in 3D bioprinting and might help to comprehend and improve the outcome of cell-printing studies in the future. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Unraveling the Role of Order-to-Disorder Transition in Shear Thickening Suspensions

DOE PAGES

Lee, Jonghun; Jiang, Zhang; Wang, Jin; ...

2018-01-09

Using high resolution in situ small angle x-ray scattering in conjunction with oscillatory shear on highly monodisperse silica suspensions, we demonstrate that an order-to-disorder transition leads to a dynamic shear thickening in a lower stress regime than the standard steady shear thickening. We show that the order-to-disorder transition is controlled by strain, which is distinguishably different from steady shear thickening which is a stress related phenomenon. The appearance of this two-step shear thinning and thickening transition is also influenced by particle size, monodispersity and measurement conditions (i.e. oscillatory shear vs. steady shear). Our results show definitively that the order-to-disorder transitionmore » induced thickening is completely unrelated to the mechanism that drives the steady shear thickening.« less
Shear Model Development of Limestone Joints with Incorporating Variations of Basic Friction Coefficient and Roughness Components During Shearing

NASA Astrophysics Data System (ADS)

Mehrishal, Seyedahmad; Sharifzadeh, Mostafa; Shahriar, Korosh; Song, Jae-Jon

2017-04-01

In relation to the shearing of rock joints, the precise and continuous evaluation of asperity interlocking, dilation, and basic friction properties has been the most important task in the modeling of shear strength. In this paper, in order to investigate these controlling factors, two types of limestone joint samples were prepared and CNL direct shear tests were performed on these joints under various shear conditions. One set of samples were travertine and another were onyx marble with slickensided surfaces, surfaces ground to #80, and rough surfaces were tested. Direct shear experiments conducted on slickensided and ground surfaces of limestone indicated that by increasing the applied normal stress, under different shearing rates, the basic friction coefficient decreased. Moreover, in the shear tests under constant normal stress and shearing rate, the basic friction coefficient remained constant for the different contact sizes. The second series of direct shear experiments in this research was conducted on tension joint samples to evaluate the effect of surface roughness on the shear behavior of the rough joints. This paper deals with the dilation and roughness interlocking using a method that characterizes the surface roughness of the joint based on a fundamental combined surface roughness concept. The application of stress-dependent basic friction and quantitative roughness parameters in the continuous modeling of the shear behavior of rock joints is an important aspect of this research.
DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Jonghun; Jiang, Zhang; Wang, Jin

Using high resolution in situ small angle x-ray scattering in conjunction with oscillatory shear on highly monodisperse silica suspensions, we demonstrate that an order-to-disorder transition leads to a dynamic shear thickening in a lower stress regime than the standard steady shear thickening. We show that the order-to-disorder transition is controlled by strain, which is distinguishably different from steady shear thickening which is a stress related phenomenon. The appearance of this two-step shear thinning and thickening transition is also influenced by particle size, monodispersity and measurement conditions (i.e. oscillatory shear vs. steady shear). Our results show definitively that the order-to-disorder transitionmore » induced thickening is completely unrelated to the mechanism that drives the steady shear thickening.« less
Direct numerical simulation of particle alignment in viscoelastic fluids

NASA Astrophysics Data System (ADS)

Hulsen, Martien; Jaensson, Nick; Anderson, Patrick

2016-11-01

Rigid particles suspended in viscoelastic fluids under shear can align in string-like structures in flow direction. To unravel this phenomenon, we present 3D direct numerical simulations of the alignment of two and three rigid, non-Brownian particles in a shear flow of a viscoelastic fluid. The equations are solved on moving, boundary-fitted meshes, which are locally refined to accurately describe the polymer stresses around and in between the particles. A small minimal gap size between the particles is introduced. The Giesekus model is used and the effect of the Weissenberg number, shear thinning and solvent viscosity is investigated. Alignment of two and three particles is observed. Morphology plots have been created for various combinations of fluid parameters. Alignment is mainly governed by the value of the elasticity parameter S, defined as half of the ratio between the first normal stress difference and shear stress of the suspending fluid. Alignment appears to occur above a critical value of S, which decreases with increasing shear thinning. This result, together with simulations of a shear-thinning Carreau fluid, leads us to the conclusion that normal stress differences are essential for particle alignment to occur, but it is also strongly promoted by shear thinning.
Origin of shear thickening in semidilute wormlike micellar solutions and evidence of elastic turbulence

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marín-Santibáñez, Benjamín M.; Pérez-González, José, E-mail: jpg@esfm.ipn.mx; Rodríguez-González, Francisco

2014-11-01

The origin of shear thickening in an equimolar semidilute wormlike micellar solution of cetylpyridinium chloride and sodium salicylate was investigated in this work by using Couette rheometry, flow visualization, and capillary Rheo-particle image velocimetry. The use of the combined methods allowed the discovery of gradient shear banding flow occurring from a critical shear stress and consisting of two main bands, one isotropic (transparent) of high viscosity and one structured (turbid) of low viscosity. Mechanical rheometry indicated macroscopic shear thinning behavior in the shear banding regime. However, local velocimetry showed that the turbid band increased its viscosity along with the shearmore » stress, even though barely reached the value of the viscosity of the isotropic phase. This shear band is the precursor of shear induced structures that subsequently give rise to the average increase in viscosity or apparent shear thickening of the solution. Further increase in the shear stress promoted the growing of the turbid band across the flow region and led to destabilization of the shear banding flow independently of the type of rheometer used, as well as to vorticity banding in Couette flow. At last, vorticity banding disappeared and the flow developed elastic turbulence with chaotic dynamics.« less
Shear-enhanced compaction in viscoplastic rocks

NASA Astrophysics Data System (ADS)

Yarushina, V. M.; Podladchikov, Y. Y.

2012-04-01

The phenomenon of mutual influence of compaction and shear deformation was repeatedly reported in the literature over the past years. Dilatancy and shear-enhanced compaction of porous rocks were experimentally observed during both rate-independent and rate-dependent inelastic deformation. Plastic pore collapse was preceding the onset of dilatancy and shear-enhanced compaction. Effective bulk viscosity is commonly used to describe compaction driven fluid flow in porous rocks. Experimental data suggest that bulk viscosity of a fluid saturated rock might be a function of both the effective pressure and the shear stress. Dilatancy and shear-enhanced compaction can alter the transport properties of rocks through their influence on permeability and compaction length scale. Recent investigations show that shear stresses in deep mantle rocks can be responsible for spontaneous development of localized melt-rich bands and segregation of small amounts of melt from the solid rock matrix through shear channeling instability. Usually it is assumed that effective viscosity is a function of porosity only. Thus coupling between compaction and shear deformation is ignored. Spherical model which considers a hollow sphere subjected to homogeneous tractions on the outer boundary as a representative elementary volume succeeded in predicting the volumetric compaction behavior of porous rocks and metals to a hydrostatic pressure in a wide range of porosities. Following the success of this simple model we propose a cylindrical model of void compaction and decompaction due to the non-hydrostatic load. The infinite viscoplastic layer with a cylindrical hole is considered as a representative volume element. The remote boundary of the volume is subjected to a homogeneous non-hydrostatic load such that plane strain conditions are fulfilled through the volume. At some critical values of remote stresses plastic zone develops around the hole. The dependence of the effective bulk viscosity on the properties of individual components as well as on the stress state is examined. We show that bulk viscosity is a function of porosity, effective pressure and shear stress. Decreasing porosity tends to increase bulk viscosity whereas increasing shear stress and increasing effective pressure reduce it.
Effect of shear stress on water and LDL transport through cultured endothelial cell monolayers.

PubMed

Kang, Hongyan; Cancel, Limary M; Tarbell, John M

2014-04-01

Previous animal experiments have shown that the transport of LDL into arterial walls is shear stress dependent. However, little work has probed shear effects on LDL transport in vitro where conditions are well defined and mechanisms are more easily explored. Therefore, we measured shear induced water and LDL fluxes across cultured bovine aortic endothelial (BAEC) monolayers in vitro and developed a three-pore model to describe the transport dynamics. Cell apoptosis was quantified by TdT-mediated dUTP nick end labeling (TUNEL) assay. We also examined the role of nitric oxide (NO) in shear induced water and LDL fluxes by incubating BAEC monolayers with an NO synthase inhibitor, NG-monomethyl-L-arginine (L-NMMA). Our results show that direct exposure of endothelial monolayers to 12 dyn/cm2 shear stress for 3 h elicited a 2.37-fold increase in water flux (Jv), a 3.00-fold increase in LDL permeability (Pe), a 1.32-fold increase in LDL uptake, and a 1.68-fold increase in apoptotic rate. L-NMMA treatment of BAEC monolayers blocked shear induced Jv response, but had no significant effect on shear responses of Pe and cell apoptosis. A long time shear exposure (12 h) of endothelial monolayers reduced Pe and apoptotic rate close to the baseline. These results suggest that an acute change in shear stress from a static baseline state induces increases in water flux that are mediated by an NO dependent mechanism. On the other hand, the permeability of endothelial monolayers to LDL is enhanced by a short term-shear application and reduced nearly to the baseline level by a longer time shear exposure, positively correlated to the leaky junctions forming around apoptotic cells. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.
Effect of shear stress on water and LDL transport through cultured endothelial cell monolayers

PubMed Central

Kang, Hongyan; Cancel, Limary M.; Tarbell, John M.

2014-01-01

Previous animal experiments have shown that the transport of LDL into arterial walls is shear stress dependent. However, little work has probed shear effects on LDL transport in vitro where conditions are well defined and mechanisms are more easily explored. Therefore, we measured shear induced water and LDL fluxes across cultured bovine aortic endothelial (BAEC) monolayers in vitro and developed a three-pore model to describe the transport dynamics. Cell apoptosis was quantified by TdT-mediated dUTP nick end labeling (TUNEL) assay. We also examined the role of nitric oxide (NO) in shear induced water and LDL fluxes by incubating BAEC monolayers with a NO synthase inhibitor, NG-monomethyl-L-arginine (L-NMMA). Our results show that direct exposure of endothelial monolayers to 12 dyn/cm2 shear stress for 3 hours elicited a 2.37-fold increase in water flux (Jv), a 3.00-fold increase in LDL permeability (Pe), a 1.32-fold increase in LDL uptake, and a 1.68-fold increase in apoptotic rate. L-NMMA treatment of BAEC monolayers blocked shear induced Jv response, but had no significant effect on shear responses of Pe and cell apoptosis. A long time shear exposure (12 h) of endothelial monolayers reduced Pe and apoptotic rate close to the baseline. These results suggest that an acute change in shear stress from a static baseline state induces increases in water flux that are mediated by a NO dependent mechanism. On the other hand, the permeability of endothelial monolayers to LDL is enhanced by a short term-shear application and reduced nearly to the baseline level by a longer time shear exposure, positively correlated to the leaky junctions forming around apoptotic cells. PMID:24583416
Stress perturbation associated with the Amazonas and other ancient continental rifts

USGS Publications Warehouse

Zoback, M.L.; Richardson, R.M.

1996-01-01

The state of stress in the vicinity of old continental rifts is examined to investigate the possibility that crustal structure associated with ancient rifts (specifically a dense rift pillow in the lower crust) may modify substantially the regional stress field. Both shallow (2.0-2.6 km depth) breakout data and deep (20-45 km depth) crustal earthquake focal mechanisms indicate a N to NNE maximum horizontal compression in the vicinity of the Paleozoic Amazonas rift in central Brazil. This compressive stress direction is nearly perpendicular to the rift structure and represents a ???75?? rotation relative to a regional E-W compressive stress direction in the South American plate. Elastic two-dimensional finite element models of the density structure associated with the Amazonas rift (as inferred from independent gravity modeling) indicate that elastic support of this dense feature would generate horizontal rift-normal compressional stresses between 60 and 120 MPa, with values of 80-100 MPa probably most representative of the overall structure. The observed ???75?? stress rotation constrains the ratio of the regional horizontal stress difference to the rift-normal compressive stress to be between 0.25 and 1.0, suggesting that this rift-normal stress may be from 1 to 4 times larger than the regional horizontal stress difference. A general expression for the modification of the normalized local horizontal shear stress (relative to the regional horizontal shear stress) shows that the same ratio of the rift-normal compression relative to the regional horizontal stress difference, which controls the amount of stress rotation, also determines whether the superposed stress increases or decreases the local maximum horizontal shear stress. The potential for fault reactivation of ancient continental rifts in general is analyzed considering both the local stress rotation and modification of horizontal shear stress for both thrust and strike-slip stress regimes. In the Amazonas rift case, because the observed stress rotation only weakly constrains the ratio of the regional horizontal stress difference to the rift-normal compression to be between 0.25 and 1.0, our analysis is inconclusive because the resultant normalized horizontal shear stress may be reduced (for ratios >0.5) or enhanced (for ratios <0.5). Additional information is needed on all three stress magnitudes to predict how a change in horizontal shear stress directly influences the likelihood of faulting in the thrust-faulting stress regime in the vicinity of the Amazonas rift. A rift-normal stress associated with the seismically active New Madrid ancient rift may be sufficient to rotate the horizontal stress field consistent with strike-slip faults parallel to the axis of the rift, although this results in a 20-40% reduction in the local horizontal shear stress within the seismic zone. Sparse stress data in the vicinity of the seismically quiescent Midcontinent rift of the central United States suggest a stress state similar to that of New Madrid, with the local horizontal shear stress potentially reduced by as much as 60%. Thus the markedly different levels of seismic activity associated with these two subparallel ancient rifts is probably due to other factors than stress perturbations due to dense rift pillows. The modeling and analysis here demonstrate that rift-normal compressive stresses are a significant source of stress acting on the lithosphere and that in some cases may be a contributing factor to the association of intraplate seismicity with old zones of continental extension.
Variability of 4D flow parameters when subjected to changes in MRI acquisition parameters using a realistic thoracic aortic phantom.

PubMed

Montalba, Cristian; Urbina, Jesus; Sotelo, Julio; Andia, Marcelo E; Tejos, Cristian; Irarrazaval, Pablo; Hurtado, Daniel E; Valverde, Israel; Uribe, Sergio

2018-04-01

To assess the variability of peak flow, mean velocity, stroke volume, and wall shear stress measurements derived from 3D cine phase contrast (4D flow) sequences under different conditions of spatial and temporal resolutions. We performed controlled experiments using a thoracic aortic phantom. The phantom was connected to a pulsatile flow pump, which simulated nine physiological conditions. For each condition, 4D flow data were acquired with different spatial and temporal resolutions. The 2D cine phase contrast and 4D flow data with the highest available spatio-temporal resolution were considered as a reference for comparison purposes. When comparing 4D flow acquisitions (spatial and temporal resolution of 2.0 × 2.0 × 2.0 mm 3 and 40 ms, respectively) with 2D phase-contrast flow acquisitions, the underestimation of peak flow, mean velocity, and stroke volume were 10.5, 10 and 5%, respectively. However, the calculated wall shear stress showed an underestimation larger than 70% for the former acquisition, with respect to 4D flow, with spatial and temporal resolution of 1.0 × 1.0 × 1.0 mm 3 and 20 ms, respectively. Peak flow, mean velocity, and stroke volume from 4D flow data are more sensitive to changes of temporal than spatial resolution, as opposed to wall shear stress, which is more sensitive to changes in spatial resolution. Magn Reson Med 79:1882-1892, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

Inhibition of bacterial and leukocyte adhesion under shear stress conditions by material surface chemistry.

PubMed

Patel, Jasmine D; Ebert, Michael; Stokes, Ken; Ward, Robert; Anderson, James M

2003-01-01

Biomaterial-centered infections, initiated by bacterial adhesion, persist due to a compromised host immune response. Altering implant materials with surface modifying endgroups (SMEs) may enhance their biocompatibility by reducing bacterial and inflammatory cell adhesion. A rotating disc model, which generates shear stress within physiological ranges, was used to characterize adhesion of leukocytes and Staphylococcus epidermidis on polycarbonate-urethanes and polyetherurethanes modified with SMEs (polyethylene oxide, fluorocarbon and dimethylsiloxane) under dynamic flow conditions. Bacterial adhesion in the absence of serum was found to be mediated by shear stress and surface chemistry, with reduced adhesion exhibited on materials modified with polydimethylsiloxane and polyethylene oxide SMEs. In contrast, bacterial adhesion was enhanced on materials modified with fluorocarbon SMEs. In the presence of serum, bacterial adhesion was primarily neither material nor shear dependent. However, bacterial adhesion in serum was significantly reduced to < or = 10% compared to adhesion in serum-free media. Leukocyte adhesion in serum exhibited a shear dependency with increased adhesion occurring in regions exposed to lower shear-stress levels of < or = 7 dyne/cm2. Additionally, polydimethylsiloxane and polyethylene oxide SMEs reduced leukocyte adhesion on polyether-urethanes. In conclusion, these results suggest that surface chemistry and shear stress can mediate bacterial and cellular adhesion. Furthermore, materials modified with polyethylene oxide SMEs are capable of inhibiting bacterial adhesion, consequently minimizing the probability of biomaterial-centered infections.
Computational analysis of integrated biosensing and shear flow in a microfluidic vascular model

NASA Astrophysics Data System (ADS)

Wong, Jeremy F.; Young, Edmond W. K.; Simmons, Craig A.

2017-11-01

Fluid flow and flow-induced shear stress are critical components of the vascular microenvironment commonly studied using microfluidic cell culture models. Microfluidic vascular models mimicking the physiological microenvironment also offer great potential for incorporating on-chip biomolecular detection. In spite of this potential, however, there are few examples of such functionality. Detection of biomolecules released by cells under flow-induced shear stress is a significant challenge due to severe sample dilution caused by the fluid flow used to generate the shear stress, frequently to the extent where the analyte is no longer detectable. In this work, we developed a computational model of a vascular microfluidic cell culture model that integrates physiological shear flow and on-chip monitoring of cell-secreted factors. Applicable to multilayer device configurations, the computational model was applied to a bilayer configuration, which has been used in numerous cell culture applications including vascular models. Guidelines were established that allow cells to be subjected to a wide range of physiological shear stress while ensuring optimal rapid transport of analyte to the biosensor surface and minimized biosensor response times. These guidelines therefore enable the development of microfluidic vascular models that integrate cell-secreted factor detection while addressing flow constraints imposed by physiological shear stress. Ultimately, this work will result in the addition of valuable functionality to microfluidic cell culture models that further fulfill their potential as labs-on-chips.
A micromechanical model to explain the mechanical properties of bovine cortical bone in tension: In vitro fluoride ion effects

NASA Astrophysics Data System (ADS)

Kotha, Shiva Prasad

Bone mineral and bone organic are assumed to be a linearly elastic, brittle material. A simple micromechanical model based on the shear lag theory is developed to model the stress transfer between the mineral platelets of bone. The bone mineral platelets carry most of the applied load while the organic primarily serves to transfer load between the overlapped mineral platelets by shear. Experiments were done to elucidate the mechanism of failure in bovine cortical bone and to decrease the mineral content of control bone with in-vitro fluoride ion treatments. It was suggested that the failure at the ultrastructural level is due to the transverse failure of bonds between the collagen microfibrils in the organic matrix. However, the shear stress transfer and the axial load bearing capacity of the organic is not impaired. Hence, it is assumed that the shear strain in the matrix increases while the shear stress remains constant at the shear yield stress once the matrix starts yielding at the ends of the bone mineral. When the shear stress over the length of the mineral platelet reaches the shear yield stress, no more applied stress is carried by the bone mineral platelets while the organic matrix carries the increased axial load. The bone fails when the axial stress in the organic reaches its ultimate stress. The bone mineral is assumed to dissolve due to in-vitro fluoride ion treatments and precipitate calcium fluoride or fluoroapatite like material. The amount of dissolution is estimated based on 19F Nuclear Magnetic Resonance or a decrease in the carbonate content of bone. The dissolution of bone mineral is assumed to increase the porosity in the organic. We assume that the elastic modulus and the ultimate strength of the organic decrease due to the increased porosity. A simple empirical model is used to model the decrease in the elastic modulus. The strength is modeled to decrease based on an increase in the cross-sectional area occupied by the porosity. The precipitate is assumed to contribute to the mechanical properties of bone due to friction generated by the poisson's contraction of the organic as it carries axial loads. The resulting stress-strain curve predicted by the model resembles the stress-strain curves obtained in the experiments.
The effect of shear flow and the density gradient on the Weibel instability growth rate in the dense plasma

NASA Astrophysics Data System (ADS)

Amininasab, S.; Sadighi-Bonabi, R.; Khodadadi Azadboni, F.

2018-02-01

Shear stress effect has been often neglected in calculation of the Weibel instability growth rate in laser-plasma interactions. In the present work, the role of the shear stress in the Weibel instability growth rate in the dense plasma with density gradient is explored. By increasing the density gradient, the shear stress threshold is increasing and the range of the propagation angles of growing modes is limited. Therefore, by increasing steps of the density gradient plasma near the relativistic electron beam-emitting region, the Weibel instability occurs at a higher stress flow. Calculations show that the minimum value of the stress rate threshold for linear polarization is greater than that of circular polarization. The Wiebel instability growth rate for linear polarization is 18.3 times circular polarization. One sees that for increasing stress and density gradient effects, there are smaller maximal growth rates for the range of the propagation angles of growing modes /π 2 < θ m i n < π and /3 π 2 < θ m i n < 2 π in circular polarized plasma and for /k c ω p < 4 in linear polarized plasma. Therefore, the shear stress and density gradient tend to stabilize the Weibel instability for /k c ω p < 4 in linear polarized plasma. Also, the shear stress and density gradient tend to stabilize the Weibel instability for the range of the propagation angles of growing modes /π 2 < θ m i n < π and /3 π 2 < θ m i n < 2 π in circular polarized plasma.
Rate Dependence in Force Networks of Sheared Granular Materials

NASA Astrophysics Data System (ADS)

Hartley, Robert; Behringer, Robert P.

2003-03-01

We describe experiments that explore rate dependence in force networks of dense granular materials undergoing slow deformation by shear and by compression. The experiments were carried out using 2D photoelastic particles so that it was possible to visualize forces at the grain scale. Shear experiments were carried out in a Couette geometry with a rate Ω. Compression experiments were carried out by repetitive compaction via a piston in a rigid chamber at comparable rates to the shear experiments. Under shearing the mean stress/force grew logarithmically with Ω for at least four decades. For compression, no dependence of the mean stress on rate was observed. In related measurements, we observed relaxation of stress in static samples that had been sheared and where the shearing was abruptly stopped. Relaxation of the force network occured over time scales of days. No relaxation of the force network was observable for uniformly compressed static samples. These results are of particular interest because they provide insight into creep and failure in granular materials.
Dynamic characteristics of Non Newtonian fluid Squeeze film damper

NASA Astrophysics Data System (ADS)

Palaksha, C. P.; Shivaprakash, S.; Jagadish, H. P.

2016-09-01

The fluids which do not follow linear relationship between rate of strain and shear stress are termed as non-Newtonian fluid. The non-Newtonian fluids are usually categorized as those in which shear stress depends on the rates of shear only, fluids for which relation between shear stress and rate of shear depends on time and the visco inelastic fluids which possess both elastic and viscous properties. It is quite difficult to provide a single constitutive relation that can be used to define a non-Newtonian fluid due to a great diversity found in its physical structure. Non-Newtonian fluids can present a complex rheological behaviour involving shear-thinning, viscoelastic or thixotropic effects. The rheological characterization of complex fluids is an important issue in many areas. The paper analyses the damping and stiffness characteristics of non-Newtonian fluids (waxy crude oil) used in squeeze film dampers using the available literature for viscosity characterization. Damping and stiffness characteristic will be evaluated as a function of shear strain rate, temperature and percentage wax concentration etc.
The influence of topographic stresses on faulting, emphasizing the 2008 Wenchuan, China earthquake rupture

NASA Astrophysics Data System (ADS)

Styron, R. H.; Hetland, E. A.; Zhang, G.

2013-12-01

The weight of large mountains produces stresses in the crust that locally may be on the order of tectonic stresses (10-100 MPa). These stresses have a significant and spatially-variable deviatoric component that may be resolved as strong normal and shear stresses on range-bounding faults. In areas of high relief, the shear stress on faults can be comparable to inferred stress drops in earthquakes, and fault-normal stresses may be greater than 50 MPa, and thus may potentially influence fault rupture. Additionally, these stresses may be used to make inferences about the orientation and magnitude of tectonic stresses, for example by indicating a minimum stress needed to be overcome by tectonic stress. We are studying these effects in several tectonic environments, such as the Longmen Shan (China), the Denali fault (Alaska, USA) and the Wasatch Fault Zone (Utah, USA). We calculate the full topographic stress tensor field in the crust in a study region by convolution of topography with Green's functions approximating stresses from a point load on the surface of an elastic halfspace, using the solution proposed by Liu and Zoback [1992]. The Green's functions are constructed from Boussinesq's solutions for a vertical point load on an elastic halfspace, as well as Cerruti's solutions for a horizontal surface point load, accounting for irregular surface boundary and topographic spreading forces. The stress tensor field is then projected onto points embedded in the halfspace representing the faults, and the fault normal and shear stresses at each point are calculated. Our primary focus has been on the 2008 Wenchuan earthquake, as this event occurred at the base of one of Earth's highest and steepest topographic fronts and had a complex and well-studied coseismic slip distribution, making it an ideal case study to evaluate topographic influence on faulting. We calculate the topographic stresses on the Beichuan and Pengguan faults, and compare the results to the coseismic slip distribution, considering several published fault models. These models differ primarily in slip magnitude and planar vs. listric fault geometry at depth. Preliminary results indicate that topographic stresses are generally resistive to tectonic deformation, especially above ~10 km depth, where the faults are steep in all models. Down-dip topographic shear stresses on the fault are normal sense where the faults dip steeply, and reach 20 MPa on the fault beneath the Pengguan massif. Reverse-sense shear up to ~15 MPa is present on gently-dipping thrust flats at depth on listric fault models. Strike-slip shear stresses are sinistral on the steep, upper portions of faults but may be dextral on thrust flats. Topographic normal stress on the faults reaches ~80 MPa on thrust ramps and may be higher on flats. Coseismic slip magnitude is negatively correlated with topographic normal and down-dip shear stresses. The spatial patterns of topographic stresses and slip suggest that topographic stresses have significantly suppressed slip in certain areas: slip maxima occur in areas of locally lower topographic stresses, while areas of higher down-dip shear and normal stress show less slip than adjacent regions.
MiR-21 is induced in endothelial cells by shear stress and modulates apoptosis and eNOS activity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weber, Martina; Baker, Meredith B.; Moore, Jeffrey P.

Mechanical forces associated with blood flow play an important role in regulating vascular signaling and gene expression in endothelial cells (ECs). MicroRNAs (miRNAs) are a class of noncoding RNAs that posttranscriptionally regulate the expression of genes involved in diverse cell functions, including differentiation, growth, proliferation, and apoptosis. miRNAs are known to have an important role in modulating EC biology, but their expression and functions in cells subjected to shear stress conditions are unknown. We sought to determine the miRNA expression profile in human ECs subjected to unidirectional shear stress and define the role of miR-21 in shear stress-induced changes inmore » EC function. TLDA array and qRT-PCR analysis performed on HUVECs exposed to prolonged unidirectional shear stress (USS, 24 h, 15 dynes/cm{sup 2}) identified 13 miRNAs whose expression was significantly upregulated (p < 0.05). The miRNA with the greatest change was miR-21; it was increased 5.2-fold (p = 0.002) in USS-treated versus control cells. Western analysis demonstrated that PTEN, a known target of miR-21, was downregulated in HUVECs exposed to USS or transfected with pre-miR-21. Importantly, HUVECs overexpressing miR-21 had decreased apoptosis and increased eNOS phosphorylation and nitric oxide (NO{sup {center_dot}}) production. These data demonstrate that shear stress forces regulate the expression of miRNAs in ECs, and that miR-21 influences endothelial biology by decreasing apoptosis and activating the NO{sup {center_dot}} pathway. These studies advance our understanding of the mechanisms by which shear stress forces modulate vascular homeostasis.« less
Critical shear stress for erosion of cohesive soils subjected to temperatures typical of wildfires

USGS Publications Warehouse

Moody, J.A.; Dungan, Smith J.; Ragan, B.W.

2005-01-01

[1] Increased erosion is a well-known response after wildfire. To predict and to model erosion on a landscape scale requires knowledge of the critical shear stress for the initiation of motion of soil particles. As this soil property is temperature-dependent, a quantitative relation between critical shear stress and the temperatures to which the soils have been subjected during a wildfire is required. In this study the critical shear stress was measured in a recirculating flume using samples of forest soil exposed to different temperatures (40??-550??C) for 1 hour. Results were obtained for four replicates of soils derived from three different types of parent material (granitic bedrock, sandstone, and volcanic tuffs). In general, the relation between critical shear stress and temperature can be separated into three different temperature ranges (275??C), which are similar to those for water repellency and temperature. The critical shear stress was most variable (1.0-2.0 N m-2) for temperatures 2.0 N m-2) between 175?? and 275??C, and was essentially constant (0.5-0.8 N m-2) for temperatures >275??C. The changes in critical shear stress with temperature were found to be essentially independent of soil type and suggest that erosion processes in burned watersheds can be modeled more simply than erosion processes in unburned watersheds. Wildfire reduces the spatial variability of soil erodibility associated with unburned watersheds by eliminating the complex effects of vegetation in protecting soils and by reducing the range of cohesion associated with different types of unburned soils. Our results indicate that modeling the erosional response after a wildfire depends primarily on determining the spatial distribution of the maximum soil temperatures that were reached during the wildfire. Copyright 2005 by the American Geophysical Union.
Critical bed shear stress and threshold of motion of maerl biogenic gravel

NASA Astrophysics Data System (ADS)

Joshi, Siddhi; Duffy, Garret Patrick; Brown, Colin

2017-07-01

A determination of the critical bed shear stress of maerl is a prerequisite for quantifying its mobility, rate of erosion and deposition in conservation management. The critical bed shear stress for incipient motion has been determined for the first time for samples from biogenic free-living maerl beds in three contrasting environments (open marine, intertidal and beach) in Galway Bay, west of Ireland. The bed shear stress was determined using two methods, Law of the Wall and Turbulent Kinetic Energy, in a rotating annular flume and in a linear flume. The velocity profile of flowing water above a bed of natural maerl grains was measured in four runs of progressively increasing flow velocity until the flow exceeded the critical shear stress of grains on the bed. The critical Shields parameter and the mobility number are estimated and compared with the equivalent curves for natural quartz sand. The critical Shields parameters for the maerl particles from all three environments fall below the Shields curve. Along with a previously reported correlation between maerl grain shape and settling velocity, these results suggest that the highly irregular shapes also allow maerl grains to be mobilised more easily than quartz grains with the same sieve diameter. The intertidal beds with the roughest particles exhibit the greatest critical shear stress because the particle thalli interlock and resist entrainment. In samples with a high percentage of maerl and low percentage of siliciclastic sand, the lower density, lower settling velocity and lower critical bed shear stress of maerl results in its preferential transport over the siliciclastic sediment. At velocities ∼10 cm s-1 higher than the threshold velocity of grain motion, rarely-documented subaqueous maerl dunes formed in the annular flume.
By activating matrix metalloproteinase-7, shear stress promotes chondrosarcoma cell motility, invasion and lung colonization.

PubMed

Guan, Pei-Pei; Yu, Xin; Guo, Jian-Jun; Wang, Yue; Wang, Tao; Li, Jia-Yi; Konstantopoulos, Konstantinos; Wang, Zhan-You; Wang, Pu

2015-04-20

Interstitial fluid flow and associated shear stress are relevant mechanical signals in cartilage and bone (patho)physiology. However, their effects on chondrosarcoma cell motility, invasion and metastasis have yet to be delineated. Using human SW1353, HS.819.T and CH2879 chondrosarcoma cell lines as model systems, we found that fluid shear stress induces the accumulation of cyclic AMP (cAMP) and interleukin-1β (IL-1β), which in turn markedly enhance chondrosarcoma cell motility and invasion via the induction of matrix metalloproteinase-7 (MMP-7). Specifically, shear-induced cAMP and IL-1β activate PI3-K, ERK1/2 and p38 signaling pathways, which lead to the synthesis of MMP-7 via transactivating NF-κB and c-Jun in human chondrosarcoma cells. Importantly, MMP-7 upregulation in response to shear stress exposure has the ability to promote lung colonization of chondrosarcomas in vivo. These findings offer a better understanding of the mechanisms underlying MMP-7 activation in shear-stimulated chondrosarcoma cells, and provide insights on designing new therapeutic strategies to interfere with chondrosarcoma invasion and metastasis.
Wind-invariant saltation heights imply linear scaling of aeolian saltation flux with shear stress.

PubMed

Martin, Raleigh L; Kok, Jasper F

2017-06-01

Wind-driven sand transport generates atmospheric dust, forms dunes, and sculpts landscapes. However, it remains unclear how the flux of particles in aeolian saltation-the wind-driven transport of sand in hopping trajectories-scales with wind speed, largely because models do not agree on how particle speeds and trajectories change with wind shear velocity. We present comprehensive measurements, from three new field sites and three published studies, showing that characteristic saltation layer heights remain approximately constant with shear velocity, in agreement with recent wind tunnel studies. These results support the assumption of constant particle speeds in recent models predicting linear scaling of saltation flux with shear stress. In contrast, our results refute widely used older models that assume that particle speed increases with shear velocity, thereby predicting nonlinear 3/2 stress-flux scaling. This conclusion is further supported by direct field measurements of saltation flux versus shear stress. Our results thus argue for adoption of linear saltation flux laws and constant saltation trajectories for modeling saltation-driven aeolian processes on Earth, Mars, and other planetary surfaces.
Wind-invariant saltation heights imply linear scaling of aeolian saltation flux with shear stress

PubMed Central

Martin, Raleigh L.; Kok, Jasper F.

2017-01-01

Wind-driven sand transport generates atmospheric dust, forms dunes, and sculpts landscapes. However, it remains unclear how the flux of particles in aeolian saltation—the wind-driven transport of sand in hopping trajectories—scales with wind speed, largely because models do not agree on how particle speeds and trajectories change with wind shear velocity. We present comprehensive measurements, from three new field sites and three published studies, showing that characteristic saltation layer heights remain approximately constant with shear velocity, in agreement with recent wind tunnel studies. These results support the assumption of constant particle speeds in recent models predicting linear scaling of saltation flux with shear stress. In contrast, our results refute widely used older models that assume that particle speed increases with shear velocity, thereby predicting nonlinear 3/2 stress-flux scaling. This conclusion is further supported by direct field measurements of saltation flux versus shear stress. Our results thus argue for adoption of linear saltation flux laws and constant saltation trajectories for modeling saltation-driven aeolian processes on Earth, Mars, and other planetary surfaces. PMID:28630907
Single-molecule force measurements of the polymerizing dimeric subunit of von Willebrand factor

NASA Astrophysics Data System (ADS)

Wijeratne, Sithara S.; Li, Jingqiang; Yeh, Hui-Chun; Nolasco, Leticia; Zhou, Zhou; Bergeron, Angela; Frey, Eric W.; Moake, Joel L.; Dong, Jing-fei; Kiang, Ching-Hwa

2016-01-01

Von Willebrand factor (VWF) multimers are large adhesive proteins that are essential to the initiation of hemostatic plugs at sites of vascular injury. The binding of VWF multimers to platelets, as well as VWF proteolysis, is regulated by shear stresses that alter VWF multimeric conformation. We used single molecule manipulation with atomic force microscopy (AFM) to investigate the effect of high fluid shear stress on soluble dimeric and multimeric forms of VWF. VWF dimers are the smallest unit that polymerizes to construct large VWF multimers. The resistance to mechanical unfolding with or without exposure to shear stress was used to evaluate VWF conformational forms. Our data indicate that, unlike recombinant VWF multimers (RVWF), recombinant dimeric VWF (RDVWF) unfolding force is not altered by high shear stress (100 dynes/cm2 for 3 min at 37°C ). We conclude that under the shear conditions used (100 dynes/cm2 for 3 min at 37°C ) , VWF dimers do not self-associate into a conformation analogous to that attained by sheared large VWF multimers.
Interlaminar shear stress effects on the postbuckling response of graphite-epoxy panels

NASA Technical Reports Server (NTRS)

Engelstad, S. P.; Reddy, J. N.; Knight, N. F., Jr.

1990-01-01

The objectives of the study are to assess the influence of shear flexibility on overall postbuckling response, and to examine transverse shear stress distributions in relation to panel failure. Nonlinear postbuckling results are obtained for finite element models based on classical laminated plate theory and first-order shear deformation theory. Good correlation between test and analysis is obtained. The results presented in this paper analytically substantiate the experimentally observed failure mode.
Imaging shear strength along subduction faults

USGS Publications Warehouse

Bletery, Quentin; Thomas, Amanda M.; Rempel, Alan W.; Hardebeck, Jeanne L.

2017-01-01

Subduction faults accumulate stress during long periods of time and release this stress suddenly, during earthquakes, when it reaches a threshold. This threshold, the shear strength, controls the occurrence and magnitude of earthquakes. We consider a 3-D model to derive an analytical expression for how the shear strength depends on the fault geometry, the convergence obliquity, frictional properties, and the stress field orientation. We then use estimates of these different parameters in Japan to infer the distribution of shear strength along a subduction fault. We show that the 2011 Mw9.0 Tohoku earthquake ruptured a fault portion characterized by unusually small variations in static shear strength. This observation is consistent with the hypothesis that large earthquakes preferentially rupture regions with relatively homogeneous shear strength. With increasing constraints on the different parameters at play, our approach could, in the future, help identify favorable locations for large earthquakes.
Numerical study of the stress state of a deformation twin in magnesium

DOE PAGES

Arul Kumar, M.; Kanjarla, A. K.; Niezgoda, S. R.; ...

2014-11-26

Here, we present a numerical study of the distribution of the local stress state associated with deformation twinning in Mg, both inside the twinned domain and in its immediate neighborhood, due to the accommodation of the twinning transformation shear. A full-field elastoviscoplastic formulation based on fast Fourier transformation is modified to include the shear transformation strain associated with deformation twinning. We performed two types of twinning transformation simulations with: (i) the twin completely embedded inside a single crystal and (ii) the twin front terminating at a grain boundary. We show that: (a) the resulting stress distribution is more strongly determinedmore » by the shear transformation than by the intragranular character of the twin or the orientation of the neighboring grain; (b) the resolved shear stress on the twin plane along the twin direction is inhomogeneous along the twin–parent interface; and (c) there are substantial differences in the average values of the shear stress in the twin and in the parent grain that contains the twin. We discuss the effect of these local stresses on twin propagation and growth, and the implications of our findings for the modeling of deformation twinning.« less
Numerical study of the stress state of a deformation twin in magnesium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Arul Kumar, M.; Kanjarla, A. K.; Niezgoda, S. R.

2015-02-01

We present here a numerical study of the distribution of the local stress state associated with deformation twinning in Mg, both inside the twinned domain and in its immediate neighborhood, due to the accommodation of the twinning transformation shear. A full-field elastoviscoplastic formulation based on fast Fourier transformation is modified to include the shear transformation strain associated with deformation twinning. We have performed two types of twinning transformation simulations with: (i) the twin completely embedded inside a single crystal and (ii) the twin front terminating at a grain boundary. We show that: (a) the resulting stress distribution is more stronglymore » determined by the shear transformation than by the intragranular character of the twin or the orientation of the neighboring grain; (b) the resolved shear stress on the twin plane along the twin direction is inhomogeneous along the twin–parent interface; and (c) there are substantial differences in the average values of the shear stress in the twin and in the parent grain that contains the twin. We discuss the effect of these local stresses on twin propagation and growth, and the implications of our findings for the modeling of deformation twinning.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, Chunfa, E-mail: chunfa.huang@case.edu; Department of Medicine, Case Western Reserve University; Rammelkamp Center for Research and Education, MetroHealth System Campus, Cleveland, OH 44106

The glomerular capillary wall, composed of endothelial cells, the glomerular basement membrane and the podocytes, is continually subjected to hemodynamic force arising from tractional stress due to blood pressure and shear stress due to blood flow. Exposure of glomeruli to abnormal hemodynamic force such as hyperfiltration is associated with glomerular injury and progressive renal disease, and the conversion of mechanical stimuli to chemical signals in the regulation of the process is poorly understood in podocytes. By examining DNA fragmentation, apoptotic nuclear changes and cytochrome c release, we found that shear stress induced cell apoptosis in cultured podocytes. Meanwhile, podocytes exposedmore » to shear stress also stimulated c-Src phosphorylation, phospholipase D (PLD) activation and mammalian target of rapamycin (mTOR) signaling. Using the antibodies against c-Src, PLD{sub 1}, and PLD{sub 2} to perform reciprocal co-immunoprecipitations and in vitro PLD activity assay, our data indicated that c-Src interacted with and activated PLD{sub 1} but not PLD{sub 2}. The inhibition of shear stress-induced c-Src phosphorylation by PP{sub 2} (a specific inhibitor of c-Src kinase) resulted in reduced PLD activity. Phosphatidic acid, produced by shear stress-induced PLD activation, stimulated mTOR signaling, and caused podocyte hypertrophy and apoptosis.« less
NK cell recruitment and exercise: Potential immunotherapeutic role of shear stress and endothelial health.

PubMed

Evans, William

2017-11-01

Positive cancer patient outcomes, including increased time to recurrent events, have been associated with increased counts and function of natural killer (NK) cells. NK cell counts and function are elevated following acute exercise, and the generally accepted mechanism of increased recruitment suggests that binding of epinephrine releases NK cells from endothelial tissue via decreases in adhesion molecules following. I propose that blood flow-induced shear stress may also play a role in NK cell recruitment from the endothelium. Additionally, shear stress may play a role in improving NK cell function by decreasing oxidative stress. The relationship between shear stress and NK cell count and function can be tested by utilizing exercise and local heating with cuff inflation. If shear stress does play an important role, NK cell count and function will be improved in the non-cuffed exercise group, but not the cuffed limb. This paper will explore the mechanisms potentially explaining exercise-induced improvements in NK cell count and function, and propose a model for investigating these mechanisms. This mechanistic insight could aid in providing a novel, safe, relatively inexpensive, and non-invasive target for immunotherapy in cancer patients. Copyright © 2017. Published by Elsevier Ltd.

High glucose attenuates shear-induced changes in endothelial hydraulic conductivity by degrading the glycocalyx.

PubMed

Lopez-Quintero, Sandra V; Cancel, Limary M; Pierides, Alexis; Antonetti, David; Spray, David C; Tarbell, John M

2013-01-01

Diabetes mellitus is a risk factor for cardiovascular disease; however, the mechanisms through which diabetes impairs homeostasis of the vasculature have not been completely elucidated. The endothelium interacts with circulating blood through the surface glycocalyx layer, which serves as a mechanosensor/transducer of fluid shear forces leading to biomolecular responses. Atherosclerosis localizes typically in regions of low or disturbed shear stress, but in diabetics, the distribution is more diffuse, suggesting that there is a fundamental difference in the way cells sense shear forces. In the present study, we examined the effect of hyperglycemia on mechanotranduction in bovine aortic endothelial cells (BAEC). After six days in high glucose media, we observed a decrease in heparan sulfate content coincident with a significant attenuation of the shear-induced hydraulic conductivity response, lower activation of eNOS after exposure to shear, and reduced cell alignment with shear stress. These studies are consistent with a diabetes-induced change to the glycocalyx altering endothelial response to shear stress that could affect the distribution of atherosclerotic plaques.
High Glucose Attenuates Shear-Induced Changes in Endothelial Hydraulic Conductivity by Degrading the Glycocalyx

PubMed Central

Lopez-Quintero, Sandra V.; Cancel, Limary M.; Pierides, Alexis; Antonetti, David; Spray, David C.; Tarbell, John M.

2013-01-01

Diabetes mellitus is a risk factor for cardiovascular disease; however, the mechanisms through which diabetes impairs homeostasis of the vasculature have not been completely elucidated. The endothelium interacts with circulating blood through the surface glycocalyx layer, which serves as a mechanosensor/transducer of fluid shear forces leading to biomolecular responses. Atherosclerosis localizes typically in regions of low or disturbed shear stress, but in diabetics, the distribution is more diffuse, suggesting that there is a fundamental difference in the way cells sense shear forces. In the present study, we examined the effect of hyperglycemia on mechanotranduction in bovine aortic endothelial cells (BAEC). After six days in high glucose media, we observed a decrease in heparan sulfate content coincident with a significant attenuation of the shear-induced hydraulic conductivity response, lower activation of eNOS after exposure to shear, and reduced cell alignment with shear stress. These studies are consistent with a diabetes-induced change to the glycocalyx altering endothelial response to shear stress that could affect the distribution of atherosclerotic plaques. PMID:24260138
Acoustic Emission Parameters of Three Gorges Sandstone during Shear Failure

NASA Astrophysics Data System (ADS)

Xu, Jiang; Liu, Yixin; Peng, Shoujian

2016-12-01

In this paper, an experimental investigation of sandstone samples from the Three Gorges during shear failure was conducted using acoustic emission (AE) and direct shear tests. The AE count rate, cumulative AE count, AE energy, and amplitude of the sandstone samples were determined. Then, the relationships among the AE signals and shearing behaviors of the samples were analyzed in order to detect micro-crack initiation and propagation and reflect shear failure. The results indicated that both the shear strength and displacement exhibited a logarithmic relationship with the displacement rate at peak levels of stress. In addition, the various characteristics of the AE signals were apparent in various situations. The AE signals corresponded with the shear stress under different displacement rates. As the displacement rate increased, the amount of accumulative damage to each specimen decreased, while the AE energy peaked earlier and more significantly. The cumulative AE count primarily increased during the post-peak period. Furthermore, the AE count rate and amplitude exhibited two peaks during the peak shear stress period due to crack coalescence and rock bridge breakage. These isolated cracks later formed larger fractures and eventually caused ruptures.
Cultivation of shear stress sensitive microorganisms in disposable bag reactor systems.

PubMed

Jonczyk, Patrick; Takenberg, Meike; Hartwig, Steffen; Beutel, Sascha; Berger, Ralf G; Scheper, Thomas

2013-09-20

Technical scale (≥5l) cultivations of shear stress sensitive microorganisms are often difficult to perform, as common bioreactors are usually designed to maximize the oxygen input into the culture medium. This is achieved by mechanical stirrers, causing high shear stress. Examples for shear stress sensitive microorganisms, for which no specific cultivation systems exist, are many anaerobic bacteria and fungi, such as basidiomycetes. In this work a disposable bag bioreactor developed for cultivation of mammalian cells was investigated to evaluate its potential to cultivate shear stress sensitive anaerobic Eubacterium ramulus and shear stress sensitive basidiomycetes Flammulina velutipes and Pleurotus sapidus. All cultivations were compared with conventional stainless steel stirred tank reactors (STR) cultivations. Good growth of all investigated microorganisms cultivated in the bag reactor was found. E. ramulus showed growth rates of μ=0.56 h⁻¹ (bag) and μ=0.53 h⁻¹ (STR). Differences concerning morphology, enzymatic activities and growth in fungal cultivations were observed. In the bag reactor growth in form of small, independent pellets was observed while STR cultivations showed intense aggregation. F. velutipes reached higher biomass concentrations (21.2 g l⁻¹ DCW vs. 16.8 g l⁻¹ DCW) and up to 2-fold higher peptidolytic activities in comparison to cell cultivation in stirred tank reactors. Copyright © 2013 Elsevier B.V. All rights reserved.
Expression of endothelin-1 and constitutional nitric oxide synthase messenger RNA in saphenous vein endothelial cells exposed to arterial flow shear stress.

PubMed

Zhu, Z G; Li, H H; Zhang, B R

1997-11-01

It has long been speculated that increased blood flow shear stress might be one of the major factors affecting the patency of grafted saphenous vein in coronary artery bypass operations. The underlying cellular and molecular mechanisms for so-called "shear stress damage" have not yet been well elucidated. Endothelial cells harvested from human saphenous vein were cultured in vitro and then exposed to a high arterial level flow shear stress in the parallel flow chamber. The expression levels of endothelin-1 and constitutional nitric oxide synthase by the endothelial cells were evaluated semiquantitatively at the gene transcription (messenger RNA) level using reverse transcription polymerase chain reaction. After 7 hours of exposure to arterial level shear stress, the expression of constitutional nitric oxide synthase messenger RNA by saphenous vein endothelial cells was significantly reduced, whereas the expression of endothelin-1 messenger RNA was substantially increased. These changes were more predominant at 24 hours. Arterial level flow shear stress could cause important changes in the gene transcription level in saphenous vein endothelial cells within a short period of time. The functional alterations of saphenous vein endothelial cells, as manifested by the increased expression of endothelin-1 and decreased expression of nitric oxide synthase messenger RNA, might play a crucial role in the vein graft remodeling process.
Dispersive aortic cannulas reduce aortic wall shear stress affecting atherosclerotic plaque embolization.

PubMed

Assmann, Alexander; Gül, Fethi; Benim, Ali Cemal; Joos, Franz; Akhyari, Payam; Lichtenberg, Artur

2015-03-01

Neurologic complications during on-pump cardiovascular surgery are often induced by mobilization of atherosclerotic plaques, which is directly related to enhanced wall shear stress. In the present study, we numerically evaluated the impact of dispersive aortic cannulas on aortic blood flow characteristics, with special regard to the resulting wall shear stress profiles. An idealized numerical model of the human aorta and its branches was created and used to model straight as well as bent dispersive aortic cannulas with meshlike tips inserted in the distal ascending aorta. Standard cannulas with straight beveled or bent tips served as controls. Using a recently optimized computing method, simulations of pulsatile and nonpulsatile extracorporeal circulation were performed. Dispersive aortic cannulas reduced the maximum and average aortic wall shear stress values to approximately 50% of those with control cannulas, while the difference in local values was even larger. Moreover, under pulsatile circulation, dispersive cannulas shortened the time period during which wall shear stress values were increased. The turbulent kinetic energy was also diminished by utilizing dispersive cannulas, reducing the risk of hemolysis. In summary, dispersive aortic cannulas decrease aortic wall shear stress and turbulence during extracorporeal circulation and may therefore reduce the risk of endothelial and blood cell damage as well as that of neurologic complications caused by atherosclerotic plaque mobilization. Copyright © 2014 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.
Modeling of flow-induced shear stress applied on 3D cellular scaffolds: Implications for vascular tissue engineering.

PubMed

Lesman, Ayelet; Blinder, Yaron; Levenberg, Shulamit

2010-02-15

Novel tissue-culture bioreactors employ flow-induced shear stress as a means of mechanical stimulation of cells. We developed a computational fluid dynamics model of the complex three-dimensional (3D) microstructure of a porous scaffold incubated in a direct perfusion bioreactor. Our model was designed to predict high shear-stress values within the physiological range of those naturally sensed by vascular cells (1-10 dyne/cm(2)), and will thereby provide suitable conditions for vascular tissue-engineering experiments. The model also accounts for cellular growth, which was designed as an added cell layer grown on all scaffold walls. Five model variants were designed, with geometric differences corresponding to cell-layer thicknesses of 0, 50, 75, 100, and 125 microm. Four inlet velocities (0.5, 1, 1.5, and 2 cm/s) were applied to each model. Wall shear-stress distribution and overall pressure drop calculations were then used to characterize the relation between flow rate, shear stress, cell-layer thickness, and pressure drop. The simulations showed that cellular growth within 3D scaffolds exposes cells to elevated shear stress, with considerably increasing average values in correlation to cell growth and inflow velocity. Our results provide in-depth analysis of the microdynamic environment of cells cultured within 3D environments, and thus provide advanced control over tissue development in vitro. 2009 Wiley Periodicals, Inc.
Estimation of shear stress by using a myocardial bridge-mural coronary artery simulating device.

PubMed

Ding, Hao; Yang, Qian; Shang, Kun; Lan, Hailian; Lv, Jie; Liu, Zhilin; Liu, Yang; Sheng, Lixing; Zeng, Yanjun

2017-01-01

This study was aimed at developing a myocardial bridge-mural coronary artery simulative device and analyzing the relationship between shear stress on the mural coronary artery and atherosclerosis. A myocardial bridge-mural coronary artery simulative device was used to simulate experiments in vitro. In the condition of maintaining any related parameters such as system temperature, average flow rate, and heart rate, we calculated and observed changes in proximal and distal mean values, and oscillatory value of shear stress on the mural coronary artery by regulating the compression level of the myocardial bridge to the mural coronary artery. Under 0% compression, no significant differences were observed in distal and proximal mean values and oscillatory value of the shear stress on the mural coronary artery. With the increase in the degree of compression, the mean shear stress at the distal end was greater than that at the proximal end, but the oscillatory value of the shear stress at the proximal end was greater than that at the distal end. The experimental results of this study indicate that myocardial bridge compression leads to abnormal hemodynamics at the proximal end of the mural coronary artery. This abnormal phenomenon is of great significance in the study of atherosclerosis hemodynamic pathogenesis, which has potential clinical value for pathological effects and treatments of myocardial bridge.
Mesoscale Phase Field Modeling of Glass Strengthening Under Triaxial Compression

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Yulan; Sun, Xin

2015-09-28

Recent hydraulic bomb and confined sleeve tests on transparent armor glass materials such as borosilicate glass and soda-lime glass showed that the glass strength was a function of confinement pressure. The measured stress-strain relation is not a straight line as most brittle materials behave under little or no confinement. Moreover, borosilicate glass exhibited a stronger compressive strength when compared to soda-lime glass, even though soda-lime has higher bulk and shear moduli as well as apparent yield strength. To better understand these experimental findings, a mesoscale phase field model is developed to simulate the nonlinear stress versus strain behaviors under confinementmore » by considering heterogeneity formation under triaxial compression and the energy barrier of a micro shear banding event (referred to as pseudo-slip hereafter) in the amorphous glass. With calibrated modeling parameters, the simulation results demonstrate that the developed phase field model can quantitatively predict the pressure-dependent strength, and it can also explain the difference between the two types of glasses from the perspective of energy barrier associated with a pseudo-slip event.« less
Computation of turbulent boundary layers employing the defect wall-function method. M.S. Thesis

NASA Technical Reports Server (NTRS)

Brown, Douglas L.

1994-01-01

In order to decrease overall computational time requirements of spatially-marching parabolized Navier-Stokes finite-difference computer code when applied to turbulent fluid flow, a wall-function methodology, originally proposed by R. Barnwell, was implemented. This numerical effort increases computational speed and calculates reasonably accurate wall shear stress spatial distributions and boundary-layer profiles. Since the wall shear stress is analytically determined from the wall-function model, the computational grid near the wall is not required to spatially resolve the laminar-viscous sublayer. Consequently, a substantially increased computational integration step size is achieved resulting in a considerable decrease in net computational time. This wall-function technique is demonstrated for adiabatic flat plate test cases from Mach 2 to Mach 8. These test cases are analytically verified employing: (1) Eckert reference method solutions, (2) experimental turbulent boundary-layer data of Mabey, and (3) finite-difference computational code solutions with fully resolved laminar-viscous sublayers. Additionally, results have been obtained for two pressure-gradient cases: (1) an adiabatic expansion corner and (2) an adiabatic compression corner.
Machine Learning of Fault Friction

NASA Astrophysics Data System (ADS)

Johnson, P. A.; Rouet-Leduc, B.; Hulbert, C.; Marone, C.; Guyer, R. A.

2017-12-01

We are applying machine learning (ML) techniques to continuous acoustic emission (AE) data from laboratory earthquake experiments. Our goal is to apply explicit ML methods to this acoustic datathe AE in order to infer frictional properties of a laboratory fault. The experiment is a double direct shear apparatus comprised of fault blocks surrounding fault gouge comprised of glass beads or quartz powder. Fault characteristics are recorded, including shear stress, applied load (bulk friction = shear stress/normal load) and shear velocity. The raw acoustic signal is continuously recorded. We rely on explicit decision tree approaches (Random Forest and Gradient Boosted Trees) that allow us to identify important features linked to the fault friction. A training procedure that employs both the AE and the recorded shear stress from the experiment is first conducted. Then, testing takes place on data the algorithm has never seen before, using only the continuous AE signal. We find that these methods provide rich information regarding frictional processes during slip (Rouet-Leduc et al., 2017a; Hulbert et al., 2017). In addition, similar machine learning approaches predict failure times, as well as slip magnitudes in some cases. We find that these methods work for both stick slip and slow slip experiments, for periodic slip and for aperiodic slip. We also derive a fundamental relationship between the AE and the friction describing the frictional behavior of any earthquake slip cycle in a given experiment (Rouet-Leduc et al., 2017b). Our goal is to ultimately scale these approaches to Earth geophysical data to probe fault friction. References Rouet-Leduc, B., C. Hulbert, N. Lubbers, K. Barros, C. Humphreys and P. A. Johnson, Machine learning predicts laboratory earthquakes, in review (2017). https://arxiv.org/abs/1702.05774Rouet-LeDuc, B. et al., Friction Laws Derived From the Acoustic Emissions of a Laboratory Fault by Machine Learning (2017), AGU Fall Meeting Session S025: Earthquake source: from the laboratory to the fieldHulbert, C., Characterizing slow slip applying machine learning (2017), AGU Fall Meeting Session S019: Slow slip, Tectonic Tremor, and the Brittle-to-Ductile Transition Zone: What mechanisms control the diversity of slow and fast earthquakes?
An Application of the Geo-Semantic Micro-services in Seamless Data-Model Integration

NASA Astrophysics Data System (ADS)

Jiang, P.; Elag, M.; Kumar, P.; Liu, R.; Hu, Y.; Marini, L.; Peckham, S. D.; Hsu, L.

2016-12-01

We are applying machine learning (ML) techniques to continuous acoustic emission (AE) data from laboratory earthquake experiments. Our goal is to apply explicit ML methods to this acoustic datathe AE in order to infer frictional properties of a laboratory fault. The experiment is a double direct shear apparatus comprised of fault blocks surrounding fault gouge comprised of glass beads or quartz powder. Fault characteristics are recorded, including shear stress, applied load (bulk friction = shear stress/normal load) and shear velocity. The raw acoustic signal is continuously recorded. We rely on explicit decision tree approaches (Random Forest and Gradient Boosted Trees) that allow us to identify important features linked to the fault friction. A training procedure that employs both the AE and the recorded shear stress from the experiment is first conducted. Then, testing takes place on data the algorithm has never seen before, using only the continuous AE signal. We find that these methods provide rich information regarding frictional processes during slip (Rouet-Leduc et al., 2017a; Hulbert et al., 2017). In addition, similar machine learning approaches predict failure times, as well as slip magnitudes in some cases. We find that these methods work for both stick slip and slow slip experiments, for periodic slip and for aperiodic slip. We also derive a fundamental relationship between the AE and the friction describing the frictional behavior of any earthquake slip cycle in a given experiment (Rouet-Leduc et al., 2017b). Our goal is to ultimately scale these approaches to Earth geophysical data to probe fault friction. References Rouet-Leduc, B., C. Hulbert, N. Lubbers, K. Barros, C. Humphreys and P. A. Johnson, Machine learning predicts laboratory earthquakes, in review (2017). https://arxiv.org/abs/1702.05774Rouet-LeDuc, B. et al., Friction Laws Derived From the Acoustic Emissions of a Laboratory Fault by Machine Learning (2017), AGU Fall Meeting Session S025: Earthquake source: from the laboratory to the fieldHulbert, C., Characterizing slow slip applying machine learning (2017), AGU Fall Meeting Session S019: Slow slip, Tectonic Tremor, and the Brittle-to-Ductile Transition Zone: What mechanisms control the diversity of slow and fast earthquakes?
Study on the Strength of GFRP/Stainless Steel Adhesive Joints Reinforced with Glass Mat

NASA Astrophysics Data System (ADS)

Iwasa, Masaaki

The adhesive strengths of glass fiber reinforced plastics/metal adhesive joints reinforced with glass mat under tensile shear loads and tensile loads were investigated analytically and experimentally. First, the stress singularity parameters of the bonding edges were analyzed by FEM for various types of adhesive joints reinforced with glass mat. The shear stress and normal stress distributions near the bonding edge can be expressed by two stress singularity parameters. Second, tensile shear tests were performed on taper lap joint and taper lap joint reinforced with glass mat and tensile tests were performed on T-type adhesive joint and T-type adhesive joint reinforced with glass mat. The relationships between the loads and the crosshead displacements were measured. We concluded that reinforcing adhesive joints has a greater effect on strength under tensile load than under tensile shear load. The adhesive joints strength reinforced with glass mat can be evaluated by using stress singularity parameters.
Diagnostic Techniques to Elucidate the Aerodynamic Performance of Acoustic Liners

NASA Technical Reports Server (NTRS)

June, Jason; Bertolucci, Brandon; Ukeiley, Lawrence; Cattafesta, Louis N., III; Sheplak, Mark

2017-01-01

In support of Topic A.2.8 of NASA NRA NNH10ZEA001N, the University of Florida (UF) has investigated the use of flow field optical diagnostic and micromachined sensor-based techniques for assessing the wall shear stress on an acoustic liner. Stereoscopic particle image velocimetry (sPIV) was used to study the velocity field over a liner in the Grazing Flow Impedance Duct (GFID). The results indicate that the use of a control volume based method to determine the wall shear stress is prone to significant error. The skin friction over the liner as measured using velocity curve fitting techniques was shown to be locally reduced behind an orifice, relative to the hard wall case in a streamwise plane centered on the orifice. The capacitive wall shear stress sensor exhibited a linear response for a range of shear stresses over a hard wall. PIV over the liner is consistent with lifting of the near wall turbulent structure as it passes over an orifice, followed by a region of low wall shear stress.
Shear Stress in Magnetorheological FInishing for Glasses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miao, C.; Shafrir, S.N.; Lambropoulos, J.C.

2009-04-28

We report in situ, simultaneous measurements of both drag and normal forces in magnetorheological finishing (MRF) for what is believed to be the first time, using a spot taking machine (STM) as a test bed to take MRF spots on stationary parts. The measurements are carried out over the entire area where material is being removed, i.e., the projected area of the MRF removal function/spot on the part surface, using a dual force sensor. This approach experimentally addresses the mechanisms governing material removal in MRF for optical glasses in terms of the hydrodynamic pressure and shear stress, applied by themore » hydrodynamic flow of magnetorheological fluid at the gap between the part surface and the STM wheel. This work demonstrates that the volumetric removal rate shows a positive linear dependence on shear stress. Shear stress exhibits a positive linear dependence on a material figure of merit that depends upon Young’s modulus, fracture toughness, and hardness. A modified Preston’s equation is proposed that better estimates MRF material removal rate for optical glasses by incorporating mechanical properties, shear stress, and velocity.« less
Shear stress in magnetorheological finishing for glasses.

PubMed

Miao, Chunlin; Shafrir, Shai N; Lambropoulos, John C; Mici, Joni; Jacobs, Stephen D

2009-05-01

We report in situ, simultaneous measurements of both drag and normal forces in magnetorheological finishing (MRF) for what is believed to be the first time, using a spot taking machine (STM) as a test bed to take MRF spots on stationary parts. The measurements are carried out over the entire area where material is being removed, i.e., the projected area of the MRF removal function/spot on the part surface, using a dual force sensor. This approach experimentally addresses the mechanisms governing material removal in MRF for optical glasses in terms of the hydrodynamic pressure and shear stress, applied by the hydrodynamic flow of magnetorheological fluid at the gap between the part surface and the STM wheel. This work demonstrates that the volumetric removal rate shows a positive linear dependence on shear stress. Shear stress exhibits a positive linear dependence on a material figure of merit that depends upon Young's modulus, fracture toughness, and hardness. A modified Preston's equation is proposed that better estimates MRF material removal rate for optical glasses by incorporating mechanical properties, shear stress, and velocity.
Repeated erosion of cohesive sediments with biofilms

NASA Astrophysics Data System (ADS)

Valentine, K.; Mariotti, G.; Fagherazzi, S.

2014-04-01

This study aims to explore the interplay between biofilms and erodability of cohesive sediments. Erosion experiments were run in four laboratory annular flumes with natural sediments. After each erosion the sediment was allowed to settle, mimicking intermittent physical processes like tidal currents and waves. The time between consecutive erosion events ranged from 1 to 12 days. Turbidity of the water column caused by sediment resuspension was used to determine the erodability of the sediments with respect to small and moderate shear stresses. Erodability was also compared on the basis of the presence of benthic biofilms, which were quantified using a Pulse-Amplitude Modulation (PAM) Underwater Fluorometer. We found that frequent erosion lead to the establishment of a weak biofilm, which reduced sediment erosion at small shear stresses (around 0.1 Pa). If prolonged periods without erosion were present, the biofilm fully established, resulting in lower erosion at moderate shear stresses (around 0.4 Pa). We conclude that an unstructured extracellular polymeric substances (EPS) matrix always affect sediment erodability at low shear stresses, while only a fully developed biofilm mat can reduce sediment erodability at moderate shear stresses.
Compression Fracture of CFRP Laminates Containing Stress Intensifications.

PubMed

Leopold, Christian; Schütt, Martin; Liebig, Wilfried V; Philipkowski, Timo; Kürten, Jonas; Schulte, Karl; Fiedler, Bodo

2017-09-05

For brittle fracture behaviour of carbon fibre reinforced plastics (CFRP) under compression, several approaches exist, which describe different mechanisms during failure, especially at stress intensifications. The failure process is not only initiated by the buckling fibres, but a shear driven fibre compressive failure beneficiaries or initiates the formation of fibres into a kink-band. Starting from this kink-band further damage can be detected, which leads to the final failure. The subject of this work is an experimental investigation on the influence of ply thickness and stacking sequence in quasi-isotropic CFRP laminates containing stress intensifications under compression loading. Different effects that influence the compression failure and the role the stacking sequence has on damage development and the resulting compressive strength are identified and discussed. The influence of stress intensifications is investigated in detail at a hole in open hole compression (OHC) tests. A proposed interrupted test approach allows identifying the mechanisms of damage initiation and propagation from the free edge of the hole by causing a distinct damage state and examine it at a precise instant of time during fracture process. Compression after impact (CAI) tests are executed in order to compare the OHC results to a different type of stress intensifications. Unnotched compression tests are carried out for comparison as a reference. With this approach, a more detailed description of the failure mechanisms during the sudden compression failure of CFRP is achieved. By microscopic examination of single plies from various specimens, the different effects that influence the compression failure are identified. First damage of fibres occurs always in 0°-ply. Fibre shear failure leads to local microbuckling and the formation and growth of a kink-band as final failure mechanisms. The formation of a kink-band and finally steady state kinking is shifted to higher compressive strains with decreasing ply thickness. Final failure mode in laminates with stress intensification depends on ply thickness. In thick or inner plies, damage initiates as shear failure and fibre buckling into the drilled hole. The kink-band orientation angle is changing with increasing strain. In outer or thin plies shear failure of single fibres is observed as first damage and the kink-band orientation angle is constant until final failure. Decreasing ply thickness increases the unnotched compressive strength. When stress intensifications are present, the position of the 0°-layer is critical for stability under compression and is thus more important than the ply thickness. Central 0°-layers show best results for OHC and CAI strength due to higher bending stiffness and better supporting effect of the adjacent layers.
Compression Fracture of CFRP Laminates Containing Stress Intensifications

PubMed Central

Schütt, Martin; Philipkowski, Timo; Kürten, Jonas; Schulte, Karl

2017-01-01

For brittle fracture behaviour of carbon fibre reinforced plastics (CFRP) under compression, several approaches exist, which describe different mechanisms during failure, especially at stress intensifications. The failure process is not only initiated by the buckling fibres, but a shear driven fibre compressive failure beneficiaries or initiates the formation of fibres into a kink-band. Starting from this kink-band further damage can be detected, which leads to the final failure. The subject of this work is an experimental investigation on the influence of ply thickness and stacking sequence in quasi-isotropic CFRP laminates containing stress intensifications under compression loading. Different effects that influence the compression failure and the role the stacking sequence has on damage development and the resulting compressive strength are identified and discussed. The influence of stress intensifications is investigated in detail at a hole in open hole compression (OHC) tests. A proposed interrupted test approach allows identifying the mechanisms of damage initiation and propagation from the free edge of the hole by causing a distinct damage state and examine it at a precise instant of time during fracture process. Compression after impact (CAI) tests are executed in order to compare the OHC results to a different type of stress intensifications. Unnotched compression tests are carried out for comparison as a reference. With this approach, a more detailed description of the failure mechanisms during the sudden compression failure of CFRP is achieved. By microscopic examination of single plies from various specimens, the different effects that influence the compression failure are identified. First damage of fibres occurs always in 0°-ply. Fibre shear failure leads to local microbuckling and the formation and growth of a kink-band as final failure mechanisms. The formation of a kink-band and finally steady state kinking is shifted to higher compressive strains with decreasing ply thickness. Final failure mode in laminates with stress intensification depends on ply thickness. In thick or inner plies, damage initiates as shear failure and fibre buckling into the drilled hole. The kink-band orientation angle is changing with increasing strain. In outer or thin plies shear failure of single fibres is observed as first damage and the kink-band orientation angle is constant until final failure. Decreasing ply thickness increases the unnotched compressive strength. When stress intensifications are present, the position of the 0°-layer is critical for stability under compression and is thus more important than the ply thickness. Central 0°-layers show best results for OHC and CAI strength due to higher bending stiffness and better supporting effect of the adjacent layers. PMID:28872623
Advanced Mobility Testbed for Dynamic Semi-Autonomous Unmanned Ground Vehicles

DTIC Science & Technology

2015-04-24

constraint, effectively hiding them from the dynamics solver. Thus the resulting system topology is once again a tree with only inter-body hinges and...the geometry of wheel sinkage (left) and stress distribution under the wheel (right) from reference [24]. With τmax(θ) = c+σ(θ) tan (φ). the shear...sliding). The transversal deflection α or lateral slip angle and the lateral slip coefficient Sα are Sα = tan (α) = −vy vx (12) The comprehensive slip ratio

Rheology linked with phase changes as recorded by development of shear bands in the South Armorican Shear Zone

NASA Astrophysics Data System (ADS)

Jeřábek, Petr; Bukovská, Zita

2015-04-01

The South Armorican Shear Zone in France represents a major right-lateral strike slip shear zone formed in the late stages of Variscan orogeny. The active deformation in this shear zone is associated with the development of S-C fabrics in granitoids where thin shear bands (C) overprint an earlier higher grade metamorphic foliation (S). In the studied samples covering low to high intensity of shear band overprint, we identified three stages of shear band evolution associated with distinct microstructures and deformation mechanisms. The initiation of shear bands stage I is associated with the formation of microcracks crosscutting the S fabric and detected namely in the recrystallized quartz aggregates. The microcracks of suitable orientation are filled by microcline, albite, muscovite and chlorite which is a typical assemblage also for the well developed shear bands. Phase equilibrium modeling in PERPLEX indicates that this assemblage formed at pressure-temperature range of 0.1-0.4 GPa and 300-340 °C. Stage II of shear band evolution is characterized by dynamic recrystallization and grain size reduction of quartz aggregates along the microcracks and replacement of quartz by microcline along grain boundaries. This process leads to disintegration of quartz aggregate fabric and phase mixing in the shear bands. The inferred deformation mechanism for this stage is solution-precipitation creep although recrystallization of quartz is still active at the contact between quartz aggregates and shear bands. The coarse grained microstructure of quartz aggregates with ca ~250 microns average grain size reduces to ~10 microns grain size when recrystallized along extremely thin shear bands/microcracks and to ~20 microns grain size when recrystallized along the thicker shear bands. By using the flow law of Patterson and Luan (1990) for dislocation creep in quartz and the quartz piezometer of Stipp and Tullis (2003) corrected after Holyoke and Kronenberg (2010), the quartz recrystallization along thin shear bands records strain rates of ~10^-14 whereas the recrystallization along thick shear bands records strain rates of ~10^-15. The contemporaneous operation of solution-precipitation creep in shear bands and dislocation creep in quartz along the shear band boundary suggests low viscosity contrast between the mixed phase shear band matrix and pure quartz aggregate implying that the solution-precipitation creep reflect similar stress and strain rate conditions as the dislocation creep in quartz. Stage III of shear band evolution is characterized by interconnection of dispersed muscovite grains and the deformation becomes accommodated by dislocation creep in thin muscovite bands separating the inactive domains of stage II microstructure. References: Holyoke III, C. W., & Kronenberg, A. K. (2010). Accurate differential stress measurement using the molten salt cell and solid salt assemblies in the Griggs apparatus with applications to strength, piezometers and rheology. Tectonophysics, 494(1-2), 17-31. Paterson, M. S., & Luan, F. C. (1990). Quartzite rheology under geological conditions. In R. J. Knipe & E. H. Rutter (Eds.), Deformation Mechanisms, Rheology and Tectonics (pp. 299-307). London: Geological Society Special Publications. Stipp, M., & Tullis, J. (2003). The recrystallized grain size piezometer for quartz. Geophysical Research Letters, 30(21), 1-5.
Rock friction under variable normal stress

USGS Publications Warehouse

Kilgore, Brian D.; Beeler, Nicholas M.; Lozos, Julian C.; Oglesby, David

2017-01-01

This study is to determine the detailed response of shear strength and other fault properties to changes in normal stress at room temperature using dry initially bare rock surfaces of granite at normal stresses between 5 and 7 MPa. Rapid normal stress changes result in gradual, approximately exponential changes in shear resistance with fault slip. The characteristic length of the exponential change is similar for both increases and decreases in normal stress. In contrast, changes in fault normal displacement and the amplitude of small high-frequency elastic waves transmitted across the surface follow a two stage response consisting of a large immediate and a smaller gradual response with slip. The characteristic slip distance of the small gradual response is significantly smaller than that of shear resistance. The stability of sliding in response to large step decreases in normal stress is well predicted using the shear resistance slip length observed in step increases. Analysis of the shear resistance and slip-time histories suggest nearly immediate changes in strength occur in response to rapid changes in normal stress; these are manifested as an immediate change in slip speed. These changes in slip speed can be qualitatively accounted for using a rate-independent strength model. Collectively, the observations and model show that acceleration or deceleration in response to normal stress change depends on the size of the change, the frictional characteristics of the fault surface, and the elastic properties of the loading system.
Prediction of soil stress-strain response incorporates mobilised shear strength envelope of granitic residual soil

NASA Astrophysics Data System (ADS)

Rahman, Abdul Samad Abdul; Noor, Mohd Jamaludin Md; Ahmad, Juhaizad Bin; Sidek, Norbaya

2017-10-01

The concept of effective stress has been the principal concept in characterizing soil volume change behavior in soil mechanics, the settlement models developed using this concept have been empirical in nature. However, there remain certain unexplained soil volume change behaviors that cannot be explained using the effective stress concept, one such behaviour is the inundation settlement. Studies have begun to indicate the inevitable role of shear strength as a critical element to be incorporated in models to unravel the unexplained soil behaviours. One soil volume change model that applies the concept of effective stress and the shear strength interaction is the Rotational Multiple Yield Surface Framework (RMYSF) model. This model has been developed from the soil-strain behavior under anisotropic stress condition. Hence, the RMYSF actually measure the soil actual elasto-plastic response to stress rather than assuming it to be fully elastic or plastic as normally perceived by the industry. The frameworks measures the increase in the mobilize shear strength when the soil undergo anisotropic settlement.
Shear stress along the conduit wall as a plausible source of tilt at Soufrière Hills volcano, Montserrat

NASA Astrophysics Data System (ADS)

Green, D. N.; Neuberg, J.; Cayol, V.

2006-05-01

Surface deformations recorded in close proximity to the active lava dome at Soufrière Hills volcano, Montserrat, can be used to infer stresses within the uppermost 1000 m of the conduit system. Most deformation source models consider only isotropic pressurisation of the conduit. We show that tilt recorded during rapid magma extrusion in 1997 could have also been generated by shear stresses sustained along the conduit wall; these stresses are a consequence of pressure gradients that develop along the conduit. Numerical modelling, incorporating realistic topography, can reproduce both the morphology and half the amplitude of the measured deformation field using a realistic shear stress amplitude, equivalent to a pressure gradient of 3.5 × 104 Pa m-1 along a 1000 m long conduit with a 15 m radius. This shear stress model has advantages over the isotropic pressure models because it does not require either physically unattainable overpressures or source radii larger than 200 m to explain the same deformation.
Endothelial cell response to biomechanical forces under simulated vascular loading conditions.

PubMed

Punchard, M A; Stenson-Cox, C; O'cearbhaill, E D; Lyons, E; Gundy, S; Murphy, L; Pandit, A; McHugh, P E; Barron, V

2007-01-01

In vivo, endothelial cells (EC) are constantly exposed to the haemodynamic forces (HF) of pressure, wall shear stress and hoop stress. The main aim of this study was to design, create and validate a novel perfusion bioreactor capable of delivering shear stress and intravascular pressure to EC in vitro and to characterise their morphology, orientation and gene expression. Here we report the creation and validation of such a simulator and the dual application of pressure (120/60 mmHg) and low shear stress (5 dyn/cm(2)) to a monolayer of EC established on a non-compliant silicone tube. Under these conditions, EC elongated and realigned obliquely to the direction of applied shear stress in a time-dependent manner. Furthermore, randomly distributed F-actin microfilaments reorganised into long, dense stress fibres crossing the cells in a direction perpendicular to that of flow. Finally, combinatorial biomechanical conditioning of EC induced the expression of the inflammatory-associated E-selectin gene.
An investigation of stress wave propagation in a shear deformable nanobeam based on modified couple stress theory

NASA Astrophysics Data System (ADS)

Akbarzadeh Khorshidi, Majid; Shariati, Mahmoud

2016-04-01

This paper presents a new investigation for propagation of stress wave in a nanobeam based on modified couple stress theory. Using Euler-Bernoulli beam theory, Timoshenko beam theory, and Reddy beam theory, the effect of shear deformation is investigated. This nonclassical model contains a material length scale parameter to capture the size effect and the Poisson effect is incorporated in the current model. Governing equations of motion are obtained by Hamilton's principle and solved explicitly. This solution leads to obtain two phase velocities for shear deformable beams in different directions. Effects of shear deformation, material length scale parameter, and Poisson's ratio on the behavior of these phase velocities are investigated and discussed. The results also show a dual behavior for phase velocities against Poisson's ratio.
Edge Fracture in Complex Fluids.

PubMed

Hemingway, Ewan J; Kusumaatmaja, Halim; Fielding, Suzanne M

2017-07-14

We study theoretically the edge fracture instability in sheared complex fluids, by means of linear stability analysis and direct nonlinear simulations. We derive an exact analytical expression for the onset of edge fracture in terms of the shear-rate derivative of the fluid's second normal stress difference, the shear-rate derivative of the shear stress, the jump in shear stress across the interface between the fluid and the outside medium (usually air), the surface tension of that interface, and the rheometer gap size. We provide a full mechanistic understanding of the edge fracture instability, carefully validated against our simulations. These findings, which are robust with respect to choice of rheological constitutive model, also suggest a possible route to mitigating edge fracture, potentially allowing experimentalists to achieve and accurately measure flows stronger than hitherto possible.
Magnetic field effects on shear and normal stresses in magnetorheological finishing.

PubMed

Lambropoulos, John C; Miao, Chunlin; Jacobs, Stephen D

2010-09-13

We use a recent experimental technique to measure in situ shear and normal stresses during magnetorheological finishing (MRF) of a borosilicate glass over a range of magnetic fields. At low fields shear stresses increase with magnetic field, but become field-independent at higher magnetic fields. Micromechanical models of formation of magnetic particle chains suggest a complex behavior of magnetorheological (MR) fluids that combines fluid- and solid-like responses. We discuss the hypothesis that, at higher fields, slip occurs between magnetic particle chains and the immersed glass part, while the normal stress is governed by the MRF ribbon elasticity.
Anisotropic stress correlations in two-dimensional liquids

DOE PAGES

Wu, Bin; Iwashita, Takuya; Egami, Takeshi

2015-03-01

In this paper we demonstrate the presence of anisotropic stress correlations in the simulated 2D liquids. Whereas the temporal correlation of macroscopic shear stress is known to contribute to viscosity via the Green-Kubo formula, the general question regarding angular dependence of the spatial correlation among atomic level stresses in liquids without external shear has not been explored. Besides the apparent anisotropicity with well-defined symmetry, we found that the characteristic length of shear stress correlation depends on temperature and follows the power law, suggesting divergence around the glass transition temperature. The anisotropy of the stress correlations can be explained in termsmore » of the inclusion model by Eshelby, based upon which we suggest that the mismatch between the atom and its nearest neighbor cage produces the atomic level stress as well as the long-range stress fields.« less
A film-based wall shear stress sensor for wall-bounded turbulent flows

NASA Astrophysics Data System (ADS)

Amili, Omid; Soria, Julio

2011-07-01

In wall-bounded turbulent flows, determination of wall shear stress is an important task. The main objective of the present work is to develop a sensor which is capable of measuring surface shear stress over an extended region applicable to wall-bounded turbulent flows. This sensor, as a direct method for measuring wall shear stress, consists of mounting a thin flexible film on the solid surface. The sensor is made of a homogeneous, isotropic, and incompressible material. The geometry and mechanical properties of the film are measured, and particles with the nominal size of 11 μm in diameter are embedded on the film's surface to act as markers. An optical technique is used to measure the film deformation caused by the flow. The film has typically deflection of less than 2% of the material thickness under maximum loading. The sensor sensitivity can be adjusted by changing the thickness of the layer or the shear modulus of the film's material. The paper reports the sensor fabrication, static and dynamic calibration procedure, and its application to a fully developed turbulent channel flow at Reynolds numbers in the range of 90,000-130,000 based on the bulk velocity and channel full height. The results are compared to alternative wall shear stress measurement methods.
Evolution of Friction and Permeability in a Propped Fracture under Shear

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Fengshou; Fang, Yi; Elsworth, Derek

We explore the evolution of friction and permeability of a propped fracture under shear. We examine the effects of normal stress, proppant thickness, proppant size, and fracture wall texture on the frictional and transport response of proppant packs confined between planar fracture surfaces. The proppant-absent and proppant-filled fractures show different frictional strength. For fractures with proppants, the frictional response is mainly controlled by the normal stress and proppant thickness. The depth of shearing-concurrent striations on fracture surfaces suggests that the magnitude of proppant embedment is controlled by the applied normal stress. Under high normal stress, the reduced friction implies thatmore » shear slip is more likely to occur on propped fractures in deeper reservoirs. The increase in the number of proppant layers, from monolayer to triple layers, significantly increases the friction of the propped fracture due to the interlocking of the particles and jamming. Permeability of the propped fracture is mainly controlled by the magnitude of the normal stress, the proppant thickness, and the proppant grain size. Permeability of the propped fracture decreases during shearing due to proppant particle crushing and related clogging. Proppants are prone to crushing if the shear loading evolves concurrently with the normal loading.« less
Evolution of Friction and Permeability in a Propped Fracture under Shear

DOE PAGES

Zhang, Fengshou; Fang, Yi; Elsworth, Derek; ...

2017-12-04

We explore the evolution of friction and permeability of a propped fracture under shear. We examine the effects of normal stress, proppant thickness, proppant size, and fracture wall texture on the frictional and transport response of proppant packs confined between planar fracture surfaces. The proppant-absent and proppant-filled fractures show different frictional strength. For fractures with proppants, the frictional response is mainly controlled by the normal stress and proppant thickness. The depth of shearing-concurrent striations on fracture surfaces suggests that the magnitude of proppant embedment is controlled by the applied normal stress. Under high normal stress, the reduced friction implies thatmore » shear slip is more likely to occur on propped fractures in deeper reservoirs. The increase in the number of proppant layers, from monolayer to triple layers, significantly increases the friction of the propped fracture due to the interlocking of the particles and jamming. Permeability of the propped fracture is mainly controlled by the magnitude of the normal stress, the proppant thickness, and the proppant grain size. Permeability of the propped fracture decreases during shearing due to proppant particle crushing and related clogging. Proppants are prone to crushing if the shear loading evolves concurrently with the normal loading.« less
Estimation of basal shear stresses from now ice-free LIA glacier forefields in the Swiss Alps

NASA Astrophysics Data System (ADS)

Fischer, Mauro; Haeberli, Wilfried; Huss, Matthias; Paul, Frank; Linsbauer, Andreas; Hoelzle, Martin

2013-04-01

In most cases, assessing the impacts of climatic changes on glaciers requires knowledge about the ice thickness distribution. Miscellaneous methodological approaches with different degrees of sophistication have been applied to model glacier thickness so far. However, all of them include significant uncertainty. By applying a parameterization scheme for ice thickness determination relying on assumptions about basal shear stress by Haeberli and Hoelzle (1995) to now ice-free glacier forefields in the Swiss Alps, basal shear stress values can be calculated based on a fast and robust experimental approach. In a GIS, the combination of recent (1973) and Little Ice Age (LIA) maximum (around 1850) glacier outlines, central flowlines, a recent Digital Elevation Model (DEM) and a DEM of glacier surface topography for the LIA maximum allows extracting local ice thickness over the forefield of individual glaciers. Subsequently, basal shear stress is calculated via the rheological assumption of perfect-plasticity relating ice thickness and surface slope to shear stress. The need of only very few input data commonly stored in glacier inventories permits an application to a large number of glaciers. Basal shear stresses are first calculated for subsamples of glaciers belonging to two test sites where the LIA maximum glacier surface is modeled with DEMs derived from accurate topographic maps for the mid 19th century. Neglecting outliers, the average resulting mean basal shear stress is around 80 kPa for the Bernina region (range 25-100 kPa) and 120 kPa (range 50-150 kPa) for the Aletsch region. For the entire Swiss Alps it is 100 kPa (range 40-175 kPa). Because complete LIA glacier surface elevation information is lacking there, a DEM is first created from reconstructed height of LIA lateral moraines and trimlines by using a simple GIS-based tool. A sensitivity analysis of the input parameters reveals that the performance of the developed approach primarily depends on the accuracy of the ice thickness determination and thus on the accuracy of the LIA DEMs used. Good results are expected for LIA valley or mountain glaciers with ice thicknesses larger than 100 m at the position of their terminus in 1973. Calculated shear stresses are representative in terms of average values over 20 to 40% of the total glacier length in 1850. Shear stresses strongly vary with glacier size, topographic conditions and climate. This study confirmed that reasonable values for mean basal shear stress of mountain glaciers can be estimated from an empirical and non-linear relation using the vertical extent as a proxy for mass turnover. The now available database could be used to independently test the plausibility of approaches applying simple flow models.
Earthquake Energy Dissipation in Light of High-Velocity, Slip-Pulse Shear Experiments

NASA Astrophysics Data System (ADS)

Reches, Z.; Liao, Z.; Chang, J. C.

2014-12-01

We investigated the energy dissipation during earthquakes by analysis of high-velocity shear experiments conducted on room-dry, solid samples of granite, tonalite, and dolomite sheared at slip-velocity of 0.0006-1m/s, and normal stress of 1-11.5MPa. The experimental fault were loaded in one of three modes: (1) Slip-pulse of abrupt, intense acceleration followed by moderate deceleration; (2) Impact by a spinning, heavy flywheel (225 kg); and (3) Constant velocity loading. We refer to energy dissipation in terms of power-density (PD=shear stress*slip-velocity; units of MW/m^2), and Coulomb-energy-density (CED= mechanical energy/normal stress; units of m). We present two aspects: Relative energy dissipation of the above loading modes, and relative energy dissipation between impact experiments and moderate earthquakes. For the first aspect, we used: (i) the lowest friction coefficient of the dynamic weakening; (ii) the work dissipated before reaching the lowest friction; and (iii) the cumulative mechanical work during the complete run. The results show that the slip-pulse/impact modes are energy efficient relatively to the constant-velocity mode as manifested by faster, more intense weakening and 50-90% lower energy dissipation. Thus, for a finite amount of pre-seismic crustal energy, the efficiency of slip-pulse would amplify earthquake instability. For the second aspect, we compare the experimental CED of the impact experiments to the reported breakdown energy (EG) of moderate earthquakes, Mw = 5.6 to 7.2 (Chang et al., 2012). In is commonly assumed that the seismic EG is a small fraction of the total earthquake energy, and as expected in 9 out of 11 examined earthquakes, EG was 0.005 to 0.07 of the experimental CED. We thus speculate that the experimental relation of Coulomb-energy-density to total slip distance, D, CED = 0.605 × D^0.933, is a reasonable estimate of total earthquake energy, a quantity that cannot be determined from seismic data.
Prediction of plantar shear stress distribution by artificial intelligence methods.

PubMed

Yavuz, Metin; Ocak, Hasan; Hetherington, Vincent J; Davis, Brian L

2009-09-01

Shear forces under the human foot are thought to be responsible for various foot pathologies such as diabetic plantar ulcers and athletic blisters. Frictional shear forces might also play a role in the metatarsalgia observed among hallux valgus (HaV) and rheumatoid arthritis (RA) patients. Due to the absence of commercial devices capable of measuring shear stress distribution, a number of linear models were developed. All of these have met with limited success. This study used nonlinear methods, specifically neural network and fuzzy logic schemes, to predict the distribution of plantar shear forces based on vertical loading parameters. In total, 73 subjects were recruited; 17 had diabetic neuropathy, 14 had HaV, 9 had RA, 11 had frequent foot blisters, and 22 were healthy. A feed-forward neural network (NN) and adaptive neurofuzzy inference system (NFIS) were built. These systems were then applied to a custom-built platform, which collected plantar pressure and shear stress data as subjects walked over the device. The inputs to both models were peak pressure, peak pressure-time integral, and time to peak pressure, and the output was peak resultant shear. Root-mean-square error (RMSE) values were calculated to test the models' accuracy. RMSE/actual shear ratio varied between 0.27 and 0.40 for NN predictions. Similarly, NFIS estimations resulted in a 0.28-0.37 ratio for local peak values in all subject groups. On the other hand, error percentages for global peak shear values were found to be in the range 11.4-44.1. These results indicate that there is no direct relationship between pressure and shear magnitudes. Future research should aim to decrease error levels by introducing shear stress dependent variables into the models.
Shear-induced intracellular loading of cells with molecules by controlled microfluidics.

PubMed

Hallow, Daniel M; Seeger, Richard A; Kamaev, Pavel P; Prado, Gustavo R; LaPlaca, Michelle C; Prausnitz, Mark R

2008-03-01

This study tested the hypothesis that controlled flow through microchannels can cause shear-induced intracellular loading of cells with molecules. The overall goal was to design a simple device to expose cells to fluid shear stress and thereby increase plasma membrane permeability. DU145 prostate cancer cells were exposed to fluid shear stress in the presence of fluorescent cell-impermeant molecules by using a cone-and-plate shearing device or high-velocity flow through microchannels. Using a syringe pump, cell suspensions were flowed through microchannels of 50-300 microm diameter drilled through Mylar sheets using an excimer laser. As quantified by flow cytometry, intracellular uptake and loss of viability correlated with the average shear stress. Optimal results were observed when exposing the cells to high shear stress for short durations in conical channels, which yielded uptake to over one-third of cells while maintaining viability at approximately 80%. This method was capable of loading cells with molecules including calcein (0.62 kDa), large molecule weight dextrans (150-2,000 kDa), and bovine serum albumin (66 kDa). These results supported the hypothesis that shear-induced intracellular uptake could be generated by flow of cell suspensions through microchannels and further led to the design of a simple, inexpensive, and effective device to deliver molecules into cells. Such a device could benefit biological research and the biotechnology industry. Copyright 2007 Wiley Periodicals, Inc.
Shear-induced intracellular loading of cells with molecules by controlled microfluidics

PubMed Central

Hallow, Daniel M.; Seeger, Richard A.; Kamaev, Pavel P.; Prado, Gustavo R.; LaPlaca, Michelle C.; Prausnitz, Mark R.

2010-01-01

This study tested the hypothesis that controlled flow through microchannels can cause shear-induced intracellular loading of cells with molecules. The overall goal was to design a simple device to expose cells to fluid shear stress and thereby increase plasma membrane permeability. DU145 prostate cancer cells were exposed to fluid shear stress in the presence of fluorescent cell-impermeant molecules by using a cone-and-plate shearing device or high-velocity flow through microchannels. Using a syringe pump, cell suspensions were flowed through microchannels of 50 – 300 μm diameter drilled through Mylar® sheets using an excimer laser. As quantified by flow cytometry, intracellular uptake and loss of viability correlated with the average shear stress. Optimal results were observed when exposing the cells to high shear stress for short durations in conical channels, which yielded uptake to over one third of cells while maintaining viability at approximately 80%. This method was capable of loading cells with molecules including calcein (0.62 kDa), large molecule weight dextrans (150 - 2000 kDa), and bovine serum albumin (66 kDa). These results supported the hypothesis that shear-induced intracellular uptake could be generated by flow of cell suspensions through microchannels and further led to the design of a simple, inexpensive, and effective device to deliver molecules into cells. Such a device could benefit biological research and the biotechnology industry. PMID:17879304
Viscoelastic analysis of a dental metal-ceramic system

NASA Astrophysics Data System (ADS)

Özüpek, Şebnem; Ünlü, Utku Cemal

2012-11-01

Porcelain-fused-to-metal (PFM) restorations used in prosthetic dentistry contain thermal stresses which develop during the cooling phase after firing. These thermal stresses coupled with the stresses produced by mechanical loads may be the dominant reasons for failures in clinical situations. For an accurate calculation of these stresses, viscoelastic behavior of ceramics at high temperatures should not be ignored. In this study, the finite element technique is used to evaluate the effect of viscoelasticity on stress distributions of a three-point flexure test specimen, which is the current international standard, ISO 9693, to characterize the interfacial bond strength of metal-ceramic restorative systems. Results indicate that the probability of interfacial debonding due to normal tensile stress is higher than that due to shear stress. This conclusion suggests modification of ISO 9693 bond strength definition from one in terms of the shear stress only to that accounting for both normal and shear stresses.
Slicken 1.0: Program for calculating the orientation of shear on reactivated faults

NASA Astrophysics Data System (ADS)

Xu, Hong; Xu, Shunshan; Nieto-Samaniego, Ángel F.; Alaniz-Álvarez, Susana A.

2017-07-01

The slip vector on a fault is an important parameter in the study of the movement history of a fault and its faulting mechanism. Although there exist many graphical programs to represent the shear stress (or slickenline) orientations on faults, programs to quantitatively calculate the orientation of fault slip based on a given stress field are scarce. In consequence, we develop Slicken 1.0, a software to rapidly calculate the orientation of maximum shear stress on any fault plane. For this direct method of calculating the resolved shear stress on a planar surface, the input data are the unit vector normal to the involved plane, the unit vectors of the three principal stress axes, and the stress ratio. The advantage of this program is that the vertical or horizontal principal stresses are not necessarily required. Due to its nimble design using Java SE 8.0, it runs on most operating systems with the corresponding Java VM. The software program will be practical for geoscience students, geologists and engineers and will help resolve a deficiency in field geology, and structural and engineering geology.
Molecular Dynamics Simulations of Shear Induced Transformations in Nitromethane

NASA Astrophysics Data System (ADS)

Larentzos, James; Steele, Brad

2017-06-01

Recent experiments demonstrate that NM undergoes explosive chemical initiation under compressive shear stress. The atomistic dynamics of the shear response of single-crystalline and bi-crystalline nitromethane (NM) are simulated using molecular dynamics simulations under high pressure conditions to aid in interpreting these experiments. The atomic interactions are described using a recently re-optimized ReaxFF-lg potential trained specifically for NM under pressure. The simulations demonstrate that the NM crystal transforms into a disordered state upon sufficient application of shear stress; its maximum value, shear angle, and atomic-scale dynamics being highly dependent on crystallographic orientation of the applied shear. Shear simulations in bi-crystalline NM show more complex behavior resulting in the appearance of the disordered state at the grain boundary.

Molecular Dynamics Simulations of Shear Induced Transformations in Nitromethane

NASA Astrophysics Data System (ADS)

Larentzos, James; Steele, Brad

Recent experiments demonstrate that NM undergoes explosive chemical initiation under compressive shear stress. The atomistic dynamics of the shear response of single-crystalline and bi-crystalline nitromethane (NM) are simulated using molecular dynamics simulations under high pressure conditions to aid in interpreting these experiments. The atomic interactions are described using a recently re-optimized ReaxFF-lg potential trained specifically for NM under pressure. The simulations demonstrate that the NM crystal transforms into a disordered state upon sufficient application of shear stress; its maximum value, shear angle, and atomic-scale dynamics being highly dependent on crystallographic orientation of the applied shear. Shear simulations in bi-crystalline NM show more complex behavior resulting in the appearance of the disordered state at the grain boundary.
Flow stress model in metal cutting

NASA Technical Reports Server (NTRS)

Black, J. T.

1978-01-01

A model for the plastic deformation that occurs in metal cutting, based on dislocation mechanics, is presented. The model explains the fundamental deformation structure that develops during machining and is based on the well known Cottrell-Stokes Law, wherein the flow stress is partitioned into two parts; an athermal part which occurs in the shear fronts (or shear bands); and a thermal part which occurs in the lamella regions. The deformation envokes the presence of a cellular dislocation distribution which always exists in the material ahead of the shear process. This 'alien' dislocation distribution either exists in the metal prior to cutting or is produced by the compressive stress field which operates in front of the shear process. The magnitude of the flow stress and direction of the shear are shown to be correlated to the stacking fault energy of the metal being cut. The model is tested with respect to energy consumption rates and found to be consistent with observed values.
"Virtual shear box" experiments of stress and slip cycling within a subduction interface mélange

NASA Astrophysics Data System (ADS)

Webber, Sam; Ellis, Susan; Fagereng, Åke

2018-04-01

What role does the progressive geometric evolution of subduction-related mélange shear zones play in the development of strain transients? We use a "virtual shear box" experiment, based on outcrop-scale observations from an ancient exhumed subduction interface - the Chrystalls Beach Complex (CBC), New Zealand - to constrain numerical models of slip processes within a meters-thick shear zone. The CBC is dominated by large, competent clasts surrounded by interconnected weak matrix. Under constant slip velocity boundary conditions, models of the CBC produce stress cycling behavior, accompanied by mixed brittle-viscous deformation. This occurs as a consequence of the reorganization of competent clasts, and the progressive development and breakdown of stress bridges as clasts mutually obstruct one another. Under constant shear stress boundary conditions, the models show periods of relative inactivity punctuated by aseismic episodic slip at rapid rates (meters per year). Such a process may contribute to the development of strain transients such as slow slip.
Effects of wall curvature on turbulence statistics

NASA Technical Reports Server (NTRS)

Moser, R. D.; Moin, P.

1985-01-01

A three-dimensional, time-dependent, direct numerical simulation of low-Reynolds number turbulent flow in a mildly curved channel was performed, and the results examined to determine the mechanism by which curvature affects wall-bounded turbulent shear flows. A spectral numerical method with about one-million modes was employed, and no explicit subgrid scale model was used. The effects of curvature on this flow were determined by comparing the concave and convex sides of the channel. The observed effects are consistent with experimental observations for mild curvature. The most significant difference in the turbulence statistics between the concave and convex sides is in the Reynolds shear stress. This is accompanied by significant differences in the terms of the Reynolds shear stress balance equations. In addition, it was found that stationary Taylor-Goertler vortices were present and that they had a significant effect on the flow by contributing to the mean Reynolds shear stress, and by enhancing the difference between the wall shear stresses.
Local shear stress and its correlation with local volume fraction in concentrated non-Brownian suspensions: Lattice Boltzmann simulation

NASA Astrophysics Data System (ADS)

Lee, Young Ki; Ahn, Kyung Hyun; Lee, Seung Jong

2014-12-01

The local shear stress of non-Brownian suspensions was investigated using the lattice Boltzmann method coupled with the smoothed profile method. Previous studies have only focused on the bulk rheology of complex fluids because the local rheology of complex fluids was not accessible due to technical limitations. In this study, the local shear stress of two-dimensional solid particle suspensions in Couette flow was investigated with the method of planes to correlate non-Newtonian fluid behavior with the structural evolution of concentrated particle suspensions. Shear thickening was successfully captured for highly concentrated suspensions at high particle Reynolds number, and both the local rheology and local structure of the suspensions were analyzed. It was also found that the linear correlation between the local particle stress and local particle volume fraction was dramatically reduced during shear thickening. These results clearly show how the change in local structure of suspensions influences the local and bulk rheology of the suspensions.
A stress-controlled shear cell for small-angle light scattering and microscopy.

PubMed

Aime, S; Ramos, L; Fromental, J M; Prévot, G; Jelinek, R; Cipelletti, L

2016-12-01

We develop and test a stress-controlled, parallel plates shear cell that can be coupled to an optical microscope or a small angle light scattering setup, for simultaneous investigation of the rheological response and the microscopic structure of soft materials under an imposed shear stress. In order to minimize friction, the cell is based on an air bearing linear stage, the stress is applied through a contactless magnetic actuator, and the strain is measured through optical sensors. We discuss the contributions of inertia and of the small residual friction to the measured signal and demonstrate the performance of our device in both oscillating and step stress experiments on a variety of viscoelastic materials.
Decoupling the effect of shear stress and stretch on tissue growth & remodeling in a vascular graft.

PubMed

van Haaften, Eline E; Wissing, Tamar B; Rutten, Marcel; Bulsink, Jurgen A; Gashi, Kujtim; van Kelle, Mathieu A J; Smits, Anthal; Bouten, Carlijn; Kurniawan, Nicholas A

2018-06-07

The success of cardiovascular tissue engineering strategies largely depends on the mechanical environment in which cells develop a neo-tissue via growth and remodeling processes. This mechanical environment is defined by the local scaffold architecture to which cells adhere, i.e., the micro-environment, and by external mechanical cues to which cells respond, i.e., hemodynamic loading. The hemodynamic environment of early-developing blood vessels consists of both shear stress (due to blood flow) and circumferential stretch (due to blood pressure). Experimental platforms that recapitulate this mechanical environment in a controlled and tunable manner are thus critical for investigating cardiovascular tissue engineering. In traditional perfusion bioreactors, however, shear stress and stretch are coupled, hampering a clear delineation of their effects on cell and tissue response. Here, we uniquely designed a bioreactor that independently combines these two types of mechanical cues in eight parallel vascular grafts. The system is computationally and experimentally validated, through finite element analysis and culture of tissue constructs respectively, to distinguish various levels of shear stress (up to 5 Pa) and cyclic stretch (up to 1.10). To illustrate the usefulness of the system, we investigated the relative contribution of cyclic stretch (1.05 at 0.5 Hz) and shear stress (1 Pa) to tissue development. Both types of hemodynamic loading contributed to cell alignment, but the contribution of shear stress overruled stretch-induced cell proliferation and matrix (i.e., collagen and glycosaminoglycan) production. At a macroscopic level, cyclic stretching led to the most linear stress-stretch response, which was not related to the presence of shear stress. In conclusion, we have developed a bioreactor that is particularly suited to further unravel the interplay between hemodynamics and in situ tissue engineering processes. Using the new system, the present work highlights the importance of hemodynamic loading to the study of developing vascular tissues.
Role of shear stress in nitric oxide-dependent modulation of renal angiotensin II vasoconstriction.

PubMed

Endlich, K; Muller, C; Barthelmebs, M; Helwig, J J

1999-08-01

1. Renal vasoconstriction in response to angiotensin II (ANGII) is known to be modulated by nitric oxide (NO). Since shear stress stimulates the release of a variety of vasoactive compounds from endothelial cells, we studied the impact of shear stress on the haemodynamic effect of ANGII in isolated perfused kidneys of rats under control conditions and during NO synthase inhibition with L-NAME (100 microM). 2. Kidneys were perfused in the presence of cyclo-oxygenase inhibitor (10 microM indomethacin) with Tyrode's solution of relative viscosity zeta=1 (low viscosity perfusate, LVP) or, in order to augment shear stress, with Tyrode's solution containing 7% Ficoll 70 of relative viscosity zeta=2 (high viscosity perfusate, HVP). 3. Vascular conductance was 3.5+/-0.4 fold larger in HVP as compared with LVP kidneys, associated with an augmentation of overall wall shear stress by 37+/-5%. During NO inhibition, vascular conductance was only 2.5+/-0.2 fold elevated in HVP vs LVP kidneys, demonstrating shear stress-induced vasodilatation by NO and non-NO/non-prostanoid compound(s). 4. ANGII (10 - 100 pM) constricted the vasculature in LVP kidneys, but was without effect in HVP kidneys. During NO inhibition, in contrast, ANGII vasoconstriction was potentiated in HVP as compared with LVP kidneys. 5. The potentiation of ANGII vasoconstriction during NO inhibition has been shown to be mediated by endothelium-derived P450 metabolites and to be sensitive to AT2 receptor blockade in our earlier studies. Accordingly, in HVP kidneys, increasing concentrations of the AT2 receptor antagonist PD123319 (5 and 500 nM) gradually abolished the potentiation of ANGII vasoconstriction during NO inhibition, but did not affect vasoconstriction in response to ANGII in LVP kidneys. 6. Our results demonstrate, that augmentation of shear stress by increasing perfusate viscosity induces vasodilatation in the rat kidney, which is partially mediated by NO. Elevated levels of shear stress attenuate renal ANGII vasoconstriction through enhanced NO production and are required for AT2 sensitive potentiation during NO inhibition.
Role of shear stress in nitric oxide-dependent modulation of renal angiotensin II vasoconstriction

PubMed Central

Endlich, Karlhans; Muller, Catherine; Barthelmebs, Mariette; Helwig, Jean-Jacques

1999-01-01

Renal vasoconstriction in response to angiotensin II (ANGII) is known to be modulated by nitric oxide (NO). Since shear stress stimulates the release of a variety of vasoactive compounds from endothelial cells, we studied the impact of shear stress on the haemodynamic effect of ANGII in isolated perfused kidneys of rats under control conditions and during NO synthase inhibition with L-NAME (100 μM).Kidneys were perfused in the presence of cyclo-oxygenase inhibitor (10 μM indomethacin) with Tyrode's solution of relative viscosity ζ=1 (low viscosity perfusate, LVP) or, in order to augment shear stress, with Tyrode's solution containing 7% Ficoll 70 of relative viscosity ζ=2 (high viscosity perfusate, HVP).Vascular conductance was 3.5±0.4 fold larger in HVP as compared with LVP kidneys, associated with an augmentation of overall wall shear stress by 37±5%. During NO inhibition, vascular conductance was only 2.5±0.2 fold elevated in HVP vs LVP kidneys, demonstrating shear stress-induced vasodilatation by NO and non-NO/non-prostanoid compound(s).ANGII (10–100 pM) constricted the vasculature in LVP kidneys, but was without effect in HVP kidneys. During NO inhibition, in contrast, ANGII vasoconstriction was potentiated in HVP as compared with LVP kidneys.The potentiation of ANGII vasoconstriction during NO inhibition has been shown to be mediated by endothelium-derived P450 metabolites and to be sensitive to AT2 receptor blockade in our earlier studies. Accordingly, in HVP kidneys, increasing concentrations of the AT2 receptor antagonist PD123319 (5 and 500 nM) gradually abolished the potentiation of ANGII vasoconstriction during NO inhibition, but did not affect vasoconstriction in response to ANGII in LVP kidneys.Our results demonstrate, that augmentation of shear stress by increasing perfusate viscosity induces vasodilatation in the rat kidney, which is partially mediated by NO. Elevated levels of shear stress attenuate renal ANGII vasoconstriction through enhanced NO production and are required for AT2 sensitive potentiation during NO inhibition. PMID:10482926
Modeling the initial mechanical response and yielding behavior of gelled crude oil

NASA Astrophysics Data System (ADS)

Lei, Chen; Gang, Liu; Xingguo, Lu; Minghai, Xu; Yuannan, Tang

2018-05-01

The initial mechanical response and yielding behavior of gelled crude oil under constant shear rate conditions were investigated. By putting the Maxwell mechanical analog and a special dashpot in parallel, a quasi-Jeffreys model was obtained. The kinetic equation of the structural parameter in the Houska model was simplified reasonably so that a simplified constitutive equation of the special dashpot was expressed. By introducing a damage factor into the constitutive equation of the special dashpot and the Maxwell mechanical analog, we established a constitutive equation of the quasi-Jeffreys model. Rheological tests of gelled crude oil were conducted by imposing constant shear rates and the relationship between the shear stress and shear strain under different shear rates was plotted. It is found that the constitutive equation can fit the experimental data well under a wide range of shear rates. Based on the fitted parameters in the quasi-Jeffreys model, the shear stress changing rules of the Maxwell mechanical analog and the special dashpot were calculated and analyzed. It is found that the critical yield strain and the corresponding shear strain where shear stress of the Maxwell analog is the maximum change slightly under different shear rates. And then a critical damage softening strain which is irrelevant to the shearing conditions was put forward to describe the yielding behavior of gelled crude oil.
Lamin A/C deficiency reduces circulating tumor cell resistance to fluid shear stress

PubMed Central

Denais, Celine; Chan, Maxine F.; Wang, Zhexiao; Lammerding, Jan

2015-01-01

Metastasis contributes to over 90% of cancer-related deaths and is initiated when cancer cells detach from the primary tumor, invade the basement membrane, and enter the circulation as circulating tumor cells (CTCs). While metastasis is viewed as an inefficient process with most CTCs dying within the bloodstream, it is evident that some CTCs are capable of resisting hemodynamic shear forces to form secondary tumors in distant tissues. We hypothesized that nuclear lamins A and C (A/C) act as key structural components within CTCs necessary to resist destruction from elevated shear forces of the bloodstream. Herein, we show that, compared with nonmalignant epithelial cells, tumor cells are resistant to elevated fluid shear forces in vitro that mimic those within the bloodstream, as evidenced by significant decreases in cellular apoptosis and necrosis. Knockdown of lamin A/C significantly reduced tumor cell resistance to fluid shear stress, with significantly increased cell death compared with parental tumor cell and nontargeting controls. Interestingly, lamin A/C knockdown increased shear stress-induced tumor cell apoptosis, but did not significantly affect cellular necrosis. These data demonstrate that lamin A/C is an important structural component that enables tumor cell resistance to fluid shear stress-mediated death in the bloodstream, and may thus facilitate survival and hematogenous metastasis of CTCs. PMID:26447202
Riverine habitat dynamics

USGS Publications Warehouse

Jacobson, R.B.

2013-01-01

The physical habitat template is a fundamental influence on riverine ecosystem structure and function. Habitat dynamics refers to the variation in habitat through space and time as the result of varying discharge and varying geomorphology. Habitat dynamics can be assessed at spatial scales ranging from the grain (the smallest resolution at which an organism relates to its environment) to the extent (the broadest resolution inclusive of all space occupied during its life cycle). In addition to a potentially broad range of spatial scales, assessments of habitat dynamics may include dynamics of both occupied and nonoccupied habitat patches because of process interactions among patches. Temporal aspects of riverine habitat dynamics can be categorized into hydrodynamics and morphodynamics. Hydrodynamics refers to habitat variation that results from changes in discharge in the absence of significant change of channel morphology and at generally low sediment-transport rates. Hydrodynamic assessments are useful in cases of relatively high flow exceedance (percent of time a flow is equaled or exceeded) or high critical shear stress, conditions that are applicable in many studies of instream flows. Morphodynamics refers to habitat variation resulting from changes to substrate conditions or channel/floodplain morphology. Morphodynamic assessments are necessary when channel and floodplain boundary conditions have been significantly changed, generally by relatively rare flood events or in rivers with low critical shear stress. Morphodynamic habitat variation can be particularly important as disturbance mechanisms that mediate population growth or for providing conditions needed for reproduction, such as channel-migration events that erode cutbanks and provide new pointbar surfaces for germination of riparian trees. Understanding of habitat dynamics is increasing in importance as societal goals shift toward restoration of riverine ecosystems. Effective investment in restoration strategies requires that the role of physical habitat is correctly diagnosed and that restoration activities address true habitat limitations, including the role of dynamic habitats.
Lithology-dependent minimum horizontal stress and in-situ stress estimate

NASA Astrophysics Data System (ADS)

Zhang, Yushuai; Zhang, Jincai

2017-04-01

Based on the generalized Hooke's law with coupling stresses and pore pressure, the minimum horizontal stress is solved with assumption that the vertical, minimum and maximum horizontal stresses are in equilibrium in the subsurface formations. From this derivation, we find that the uniaxial strain method is the minimum value or lower bound of the minimum stress. Using Anderson's faulting theory and this lower bound of the minimum horizontal stress, the coefficient of friction of the fault is derived. It shows that the coefficient of friction may have a much smaller value than what it is commonly assumed (e.g., μf = 0.6-0.7) for in-situ stress estimate. Using the derived coefficient of friction, an improved stress polygon is drawn, which can reduce the uncertainty of in-situ stress calculation by narrowing the area of the conventional stress polygon. It also shows that the coefficient of friction of the fault is dependent on lithology. For example, if the formation in the fault is composed of weak shales, then the coefficient of friction of the fault may be small (as low as μf = 0.2). This implies that this fault is weaker and more likely to have shear failures than the fault composed of sandstones. To avoid the weak fault from shear sliding, it needs to have a higher minimum stress and a lower shear stress. That is, the critically stressed weak fault maintains a higher minimum stress, which explains why a low shear stress appears in the frictionally weak fault.
Global Omori law decay of triggered earthquakes: large aftershocks outside the classical aftershock zone

USGS Publications Warehouse

Parsons, Tom

2002-01-01

Triggered earthquakes can be large, damaging, and lethal as evidenced by the 1999 shocks in Turkey and the 2001 earthquakes in El Salvador. In this study, earthquakes with Ms ≥ 7.0 from the Harvard centroid moment tensor (CMT) catalog are modeled as dislocations to calculate shear stress changes on subsequent earthquake rupture planes near enough to be affected. About 61% of earthquakes that occurred near (defined as having shear stress change ∣Δτ∣ ≥ 0.01 MPa) the Ms ≥ 7.0 shocks are associated with calculated shear stress increases, while ∼39% are associated with shear stress decreases. If earthquakes associated with calculated shear stress increases are interpreted as triggered, then such events make up at least 8% of the CMT catalog. Globally, these triggered earthquakes obey an Omori law rate decay that lasts between ∼7–11 years after the main shock. Earthquakes associated with calculated shear stress increases occur at higher rates than background up to 240 km away from the main shock centroid. Omori's law is one of the few time-predictable patterns evident in the global occurrence of earthquakes. If large triggered earthquakes habitually obey Omori's law, then their hazard can be more readily assessed. The characteristic rate change with time and spatial distribution can be used to rapidly assess the likelihood of triggered earthquakes following events of Ms ≥ 7.0. I show an example application to the M = 7.7 13 January 2001 El Salvador earthquake where use of global statistics appears to provide a better rapid hazard estimate than Coulomb stress change calculations.
Global Omori law decay of triggered earthquakes: Large aftershocks outside the classical aftershock zone

USGS Publications Warehouse

Parsons, T.

2002-01-01

Triggered earthquakes can be large, damaging, and lethal as evidenced by the 1999 shocks in Turkey and the 2001 earthquakes in El Salvador. In this study, earthquakes with Ms ≥ 7.0 from the Harvard centroid moment tensor (CMT) catalog are modeled as dislocations to calculate shear stress changes on subsequent earthquake rupture planes near enough to be affected. About 61% of earthquakes that occured near (defined as having shear stress change |Δ| 0.01 MPa) the Ms ≥ 7.0 shocks are associated with calculated shear stress increases, while ~39% are associated with shear stress decreases. If earthquakes associated with calculated shear stress increases are interpreted as triggered, then such events make up at least 8% of the CMT catalog. Globally, these triggered earthquakes obey an Omori law rate decay that lasts between ~7-11 years after the main shock. Earthquakes associated with calculated shear stress increases occur at higher rates than background up to 240 km away from the main shock centroid. Omori's law is one of the few time-predictable patterns evident in the global occurrence of earthquakes. If large triggered earthquakes habitually obey Omori's law, then their hazard can be more readily assessed. The characteristics rate change with time and spatial distribution can be used to rapidly assess the likelihood of triggered earthquakes following events of Ms ≥7.0. I show an example application to the M = 7.7 13 January 2001 El Salvador earthquake where use of global statistics appears to provide a better rapid hazard estimate than Coulomb stress change calculations.
Global Omori law decay of triggered earthquakes: Large aftershocks outside the classical aftershock zone

NASA Astrophysics Data System (ADS)

Parsons, Tom

2002-09-01

Triggered earthquakes can be large, damaging, and lethal as evidenced by the1999 shocks in Turkey and the 2001 earthquakes in El Salvador. In this study, earthquakes with Ms ≥ 7.0 from the Harvard centroid moment tensor (CMT) catalog are modeled as dislocations to calculate shear stress changes on subsequent earthquake rupture planes near enough to be affected. About 61% of earthquakes that occurred near (defined as having shear stress change ∣Δτ∣ ≥ 0.01 MPa) the Ms ≥ 7.0 shocks are associated with calculated shear stress increases, while ˜39% are associated with shear stress decreases. If earthquakes associated with calculated shear stress increases are interpreted as triggered, then such events make up at least 8% of the CMT catalog. Globally, these triggered earthquakes obey an Omori law rate decay that lasts between ˜7-11 years after the main shock. Earthquakes associated with calculated shear stress increases occur at higher rates than background up to 240 km away from the main shock centroid. Omori's law is one of the few time-predictable patterns evident in the global occurrence of earthquakes. If large triggered earthquakes habitually obey Omori's law, then their hazard can be more readily assessed. The characteristic rate change with time and spatial distribution can be used to rapidly assess the likelihood of triggered earthquakes following events of Ms ≥ 7.0. I show an example application to the M = 7.7 13 January 2001 El Salvador earthquake where use of global statistics appears to provide a better rapid hazard estimate than Coulomb stress change calculations.
An Evaluation of the Iosipescu Specimen for Composite Materials Shear Property Measurement. Ph.D. Thesis

NASA Technical Reports Server (NTRS)

Ho, Henjen

1991-01-01

A detailed evaluation of the suitability of the Iosipescu specimen tested in the modified Wyoming fixture is presented. An experimental investigation using conventional strain gage instrumentation and moire interferometry is performed. A finite element analysis of the Iosipescu shear test for unidirectional and cross-ply composites is used to assess the uniformity of the shear stress field in the vicinity of the notch, and demonstrate the effect of the nonuniform stress field upon the strain gage measurements used for the determination of composite shear moduli. From the test results for graphite-epoxy laminates, it is shown that the proximity of the load introduction point to the test section greatly influences the individual gage readings for certain fiber orientations but the effect upon shear modulus measurement is relatively unimportant. A numerical study of the load contact effect shows the sensitivity of some fiber configurations to the specimen/fixture contact mechanism and may account for the variations in the measured shear moduli. A comparison of the strain gage readings from one surface of a specimen with corresponding data from moire interferometry on the opposite face documented an extreme sensitivity of some fiber orientations to eccentric loading which induced twisting and yielded spurious shear stress-strain curves. In the numerical analysis, it is shown that the Iosipescu specimens for different fiber orientations have to be modeled differently in order to closely approximate the true loading conditions. Correction factors are needed to allow for the nonuniformity of the strain field and the use of the average shear stress in the shear modulus evaluation. The correction factors, which are determined for the region occupied by the strain gage rosette, are found to be dependent upon the material orthotropic ratio and the finite element models. Based upon the experimental and numerical results, recommendations for improving the reliability and accuracy of the shear modulus values are made, and the implications for shear strength measurement discussed. Further application of the Iosipescu shear test to woven fabric composites is presented. The limitations of the traditional strain gage instrumentation on the satin weave and high tow plain weave fabrics is discussed. Test results of a epoxy based aluminum particulate composite is also presented. A modification of the Iosipescu specimen is proposed and investigated experimentally and numerically. It is shown that the proposed new specimen design provides a more uniform shear stress field in the test section and greatly reduces the normal and shear stress concentrations in the vicinity of the notches. While the fabrication and the material cost of the proposed specimen is tremendously reduced, it is shown the accuracy of the shear modulus measurement is not sacrificed.
Tuning Shear Jamming by Basal Assisted Couette Shear

NASA Astrophysics Data System (ADS)

Zhao, Yiqiu; Barés, Jonathan; Behringer, Robert

Granular matter with packing fraction ϕS < ϕ <ϕJ can be jammed by applying shear strain. However, the stress-strain relation in shear jamming transition is not very well understood. Part of the difficulty is that the strain inside the granular system is very complicated and hard to control. In this work, by using a novel Couette shear apparatus capable of generating arbitrary shear profiles, we study the stress-strain relation during shear jamming transition for granular system under different kinds of controlled interior strain. The novel Couette shear apparatus consists of 21 independently movable rings and two circular boundaries. The apparatus can shear the granular sample not only from the boundaries but also from the bottom. The granular sample is made of about 2000 bi-disperse photo elastic disks, making it possible to extract force information. This work is supported by NSF-DMR1206351, DMS1248071, NASA NNX15AD38G.
Theoretical study of corrugated plates: Shearing of a trapezoidally corrugated plate with trough lines permitted to curve

NASA Technical Reports Server (NTRS)

Lin, C.; Libove, C.

1971-01-01

A theoretical analysis is presented of the elastic shearing of a trapezoidally corrugated plate with discrete attachments at the ends of the corrugations. Numerical results on effective shear stiffness, stresses, and displacements are presented for selected geometries and end-attachment conditions. It is shown that the frame-like deformation of the cross-sections, which results from the absence of continuous end attachments, can lead to large transverse bending stresses and large reductions in shearing stiffness.
Method for measuring surface shear stress magnitude and direction using liquid crystal coatings

NASA Technical Reports Server (NTRS)

Reda, Daniel C. (Inventor)

1995-01-01

A method is provided for determining surface shear magnitude and direction at every point on a surface. The surface is covered with a shear stress sensitive liquid crystal coating and illuminated by white light from a normal direction. A video camera is positioned at an oblique angle above the surface to observe the color of the liquid crystal at that angle. The shear magnitude and direction are derived from the color information. A method of calibrating the device is also provided.

Tracing the Pathway from Drift-Wave Turbulence with Broken Symmetry to the Production of Sheared Axial Mean Flow

NASA Astrophysics Data System (ADS)

Hong, R.; Li, J. C.; Chakraborty Thakur, S.; Hajjar, R.; Diamond, P. H.; Tynan, G. R.

2018-05-01

This study traces the emergence of sheared axial flow from collisional drift-wave turbulence with broken symmetry in a linear plasma device—the controlled shear decorrelation experiment. As the density profile steepens, the axial Reynolds stress develops and drives a radially sheared axial flow that is parallel to the magnetic field. Results show that the nondiffusive piece of the Reynolds stress is driven by the density gradient, results from spectral asymmetry of the turbulence, and, thus, is dynamical in origin. Taken together, these findings constitute the first simultaneous demonstration of the causal link between the density gradient, turbulence, and stress with broken spectral symmetry and the mean axial flow.
High shear microfluidics and its application in rheological measurement

NASA Astrophysics Data System (ADS)

Kang, Kai; Lee, L. James; Koelling, Kurt W.

2005-02-01

High shear rheology was explored experimentally in microchannels (150×150 μm). Two aqueous polymer solutions, polyethylene oxide (viscoelastic fluid) and hydroxyethyl cellulose (viscous fluid) were tested. Bagley correction was applied to remove the end effect. Wall slip was investigated with Mooney’s analysis. Shear rates as high as 106 s-1 were obtained in the pressure-driven microchannel flow, allowing a smooth extension of the low shear rheological data obtained from the conventional rheometers. At high shear rates, polymer degradation was observed for PEO solutions at a critical microchannel wall shear stress of 4.1×103 Pa. Stresses at the ends of the microchannel also contributed to PEO degradation significantly.
A new understanding of fluid-rock deformation

NASA Astrophysics Data System (ADS)

Crampin, Stuart; Gao, Yuan

2015-04-01

Cracks in the pavement show that rock is weak to shear stress. Consequently we have a conundrum. How does in situ rock accumulate the enormous shear-stress energy necessary for release by a large magnitude earthquake without fracturing in smaller earthquakes? For example: observations of changes in seismic shear-wave splitting (SWS) were observed in Iceland before the 2004 Mw9.2 Sumatra-Andaman Earthquake (SAE) at a distance of ~10,500km (the width of the Eurasian Plate) from Indonesia. Observations of SWS monitor microcrack geometry, and the changes in SWS in Iceland indicated that stress-changes before the Sumatra earthquake modified microcrack geometry the width of Eurasia from Indonesia. What is the mechanism for such widespread accumulation of necessarily weak stress? We show that stress is stored in in situ rock by the stress-controlled geometry of the fluid-saturated stress-aligned microcrack. Microcrack aspect-ratios are aligned by fluid flow or dispersion along pressure-gradients between neighbouring microcracks at different orientations to the stress-field by a mechanism known as Anisotropic Poro-Elasticity or APE. Since the minimum stress is typically horizontal, the microcracks are typically vertically-oriented parallel to the maximum horizontal stress as is confirmed by observations of SWS. Such azimuthally varying shear-wave splitting (SWS) is observed in situ rocks in the upper crust, lower crust, and uppermost ~400km of the mantle. (The 'microcracks' in the mantle are intergranular films of hydrolysed melt.) SWS shows that the microcracks are so closely spaced that they verge on fracturing/earthquakes. Phenomena verging on failure are critical-systems with 'butterfly wings' sensitivity. Critical-systems are very common and it must be expected that the Earth, an archetypal complex heterogeneous interactive phenomena is a critical-system. Monitoring SWS above small earthquakes allows stress-accumulation before earthquakes to be recognised and the time, magnitude, and in some circumstances fault-plane to stress-forecast. Currently, the time, magnitude, and fault-plane of a M5 earthquake in SW Iceland was stress-forecast three-days before it occurred, and characteristic anomalies in SWS have been recognised retrospectively before ~16 other earthquakes. Stress in the Earth is generated by plate-interactions at mid-oceanic ridges and subduction zones. The behaviour of SWS suggests the following scenario. Initially, the increasing stress-field has does not recognise the location or timing of the eventual earthquake where the stress will be released. Stress continues to increase until levels of cracking known as fracture-criticality are approached around the (usually) previous (but more rarely new) fault-plane, and there is stress-relaxation as microcracks begin to coalesce on the fault. Eventually, stress is concentrated on the heavily microcracked rock and the earthquake occurs. It is believed that the APE deformation of fluid-saturated microcrack geometry pervading most rocks above ~400km in the mantle is the mechanism controlling many aspects of fluid-rock deformation. It has the advantage that the internal behavior of stress-induced manipulation of the microcrack geometry can be monitored by observations of SWS. Papers referring to these developments can be found in geos.ed.ac.uk/home/scrampin/opinion. Also see Crampin & Gao (Session SM1.1), Liu & Crampin (Session NH2.5), and Crampin & Gao (Session GD.1) at this EGU2015 meeting.
The effect of transverse shear in a cracked plate under skew-symmetric loading

NASA Technical Reports Server (NTRS)

Delale, F.; Erdogan, F.

1979-01-01

The problem of an elastic plate containing a through crack and subjected to twisting moments or transverse shear loads is considered. By using a bending theory which allows the satisfaction of the boundary conditions on the crack surface regarding the normal and the twisting moments and the transverse shear load separately, it is found that the resulting asymptotic stress field around the crack tip becomes identical to that given by the elasticity solutions of the plane strain and antiplane shear problems. The problem is solved for uniformly distributed or concentrated twisting moment or transverse shear load and the normalized Mode II and Mode III stress-intensity factors are tabulated. The results also include the effect of the Poisson's ratio and material orthotropy for specially orthotropic materials on the stress-intensity factors.
Fluid shear stress and tumor metastasis

PubMed Central

Huang, Qiong; Hu, Xingbin; He, Wanming; Zhao, Yang; Hao, Shihui; Wu, Qijing; Li, Shaowei; Zhang, Shuyi; Shi, Min

2018-01-01

The tumor microenvironment (TME) is a key factor regulating tumor cell invasion and metastasis. The effects of biochemical factors such as stromal cells, immune cells, and cytokines have been previously investigated. Owing to restrictions by the natural barrier between physical and biochemical disciplines, the role of physical factors in tumorigenesis is unclear. However, with the emergence of interdisciplinary mechanobiology and continuous advancements therein in the past 30 years, studies on the effect of physical properties such as hardness or shear stress on tumorigenesis and tumor progression are constantly renewing our understanding of mechanotransduction mechanisms. Shear stress, induced by liquid flow, is known to actively participate in proliferation, apoptosis, invasion, and metastasis of tumor cells. The present review discusses the progress and achievements in studies on tumor fluid microenvironment in recent years, especially fluid shear stress, on tumor metastasis, and presents directions for future study.
Runge-Kutta method for wall shear stress of blood flow in stenosed artery

NASA Astrophysics Data System (ADS)

Awaludin, Izyan Syazana; Ahmad, Rokiah@Rozita

2014-06-01

A mathematical model of blood flow through stenotic artery is considered. A stenosis is defined as the partial occlusion of the blood vessels due to the accumulation of cholesterols, fats and the abnormal growth of tissue on the artery walls. The development of stenosis in the artery is one of the factors that cause problem in blood circulation system. This study was conducted to determine the wall shear stress of blood flow in stenosed artery. Modified mathematical model is used to analyze the relationship of the wall shear stress versus the length and height of stenosis. The existing models that have been created by previous researchers are solved using fourth order Runge-Kutta method. Numerical results show that the wall shear stress is proportionate to the length and height of stenosis.
Shear load transfer in high and low stress tendons.

PubMed

Kondratko-Mittnacht, Jaclyn; Duenwald-Kuehl, Sarah; Lakes, Roderic; Vanderby, Ray

2015-05-01

Tendon is an integral part of joint movement and stability, as it functions to transmit load from muscle to bone. It has an anisotropic, fibrous hierarchical structure that is generally loaded in the direction of its fibers/fascicles. Internal load distributions are altered when joint motion rotates an insertion site or when local damage disrupts fibers/fascicles, potentially causing inter-fiber (or inter-fascicular) shear. Tendons with different microstructures (helical versus linear) may redistribute loads differently. This study explored how shear redistributes axial loads in rat tail tendon (low stress tendons with linear microstructure) and porcine flexor tendon (high stress with helical microstructure) by creating lacerations on opposite sides of the tendon, ranging from about 20% to 60% of the tendon width, to create various magnitudes of shear. Differences in fascicular orientation were quantified using polarized light microscopy. Unexpectedly, both tendon types maintained about 20% of pre-laceration stress values after overlapping cuts of 60% of tendon width (no intact fibers end to end) suggesting that shear stress transfer can contribute more to overall tendon strength and stiffness than previously reported. All structural parameters for both tendon types decreased linearly with increasing laceration depth. The tail tendon had a more rapid decline in post-laceration elastic stress and modulus parameters as well as a more linear and less tightly packed fascicular structure, suggesting that positional tendons may be less well suited to redistribute loads via a shear mechanism. Copyright © 2015 Elsevier Ltd. All rights reserved.
Shear Load Transfer in High and Low Stress Tendons

PubMed Central

Kondratko-Mittnacht, Jaclyn; Duenwald-Kuehl, Sarah; Lakes, Roderic; Vanderby, Ray

2016-01-01

Background Tendon is an integral part of joint movement and stability, as it functions to transmit load from muscle to bone. It has an anisotropic, fibrous hierarchical structure that is generally loaded in the direction of its fibers/fascicles. Internal load distributions are altered when joint motion rotates an insertion site or when local damage disrupts fibers/fascicles, potentially causing inter-fiber (or inter-fascicular) shear. Tendons with different microstructure (helical versus linear) may redistribute loads differently. Method of Approach This study explored how shear redistributes axial loads in rat tail tendon (low stress tendons with linear microstructure) and porcine flexor tendon (high stress with helical microstructure) by creating lacerations on opposite sides of the tendon, ranging from about 20-60% of the tendon width, to create various magnitudes of shear. Differences in fascicular orientation were quantified using polarized light microscopy. Results and Conclusions Unexpectedly, both tendon types maintained about 20% of pre-laceration stress values after overlapping cuts of 60% of tendon width (no intact fibers end to end) suggesting that shear stress transfer can contribute more to overall tendon strength and stiffness than previously reported. All structural parameters for both tendon types decreased linearly with increasing laceration depth. The tail tendon had a more rapid decline in post-laceration elastic stress and modulus parameters as well as a more linear and less tightly packed fascicular structure, suggesting that positional tendons may be less well suited to redistribute loads via a shear mechanism. PMID:25700261
FEM Modeling of In-Plane Stress Distribution in Thick Brittle Coatings/Films on Ductile Substrates Subjected to Tensile Stress to Determine Interfacial Strength.

PubMed

Wang, Kaishi; Zhang, Fangzhou; Bordia, Rajendra K

2018-03-27

The ceramic-metal interface is present in various material structures and devices that are vulnerable to failures, like cracking, which are typically due to their incompatible properties, e.g., thermal expansion mismatch. In failure of these multilayer systems, interfacial shear strength is a good measure of the robustness of interfaces, especially for planar films. There is a widely-used shear lag model and method by Agrawal and Raj to analyse and measure the interfacial shear strength of thin brittle film on ductile substrates. The use of this classical model for a type of polymer derived ceramic coatings (thickness ~18 μm) on steel substrate leads to high values of interfacial shear strength. Here, we present finite element simulations for such a coating system when it is subjected to in-plane tension. Results show that the in-plane stresses in the coating are non-uniform, i.e., varying across the thickness of the film. Therefore, they do not meet one of the basic assumptions of the classical model: uniform in-plane stress. Furthermore, effects of three significant parameters, film thickness, crack spacing, and Young's modulus, on the in-plane stress distribution have also been investigated. 'Thickness-averaged In-plane Stress' (TIS), a new failure criterion, is proposed for estimating the interfacial shear strength, which leads to a more realistic estimation of the tensile strength and interfacial shear strength of thick brittle films/coatings on ductile substrates.
The role of peel stresses in cyclic debonding

NASA Technical Reports Server (NTRS)

Everett, R. A., Jr.

1982-01-01

When an adhesively bonded joint is undergoing cyclic loading, one of the possible damage modes that occurs is called cyclic debonding - progressive separation of the adherends by failure of the adhesive bond under cyclic loading. In most practical structures, both peel and shear stresses exist in the adhesive bonding during cyclic loading. The results of an experimental and analytical study to determine the role of peel stresses on cyclic debonding in a mixed mode specimen are presented. Experimentally, this was done by controlling the forces that create the peel stresses by applying a clamping force to oppose the peel stresses. Cracked lap shear joints were chosen for this study. A finite element analysis was developed to assess the effect of the clamping force on the strain energy release rates due to shear and peel stresses. The results imply that the peel stress is the principal stress causing cyclic debonding.
Development of a directional sensitive pressure and shear sensor

NASA Astrophysics Data System (ADS)

Wang, Wei-Chih; Dee, Jeffrey; Ledoux, William; Sangeorzan, Bruce; Reinhall, Per G.

2002-06-01

Diabetes mellitus is a disease that impacts the lives of millions of people around the world. Lower limb complications associated with diabetes include the development of plantar ulcers that can lead to infection and subsequent amputation. Shear stress is thought to be a major contributing factor to ulcer development, but due in part to technical difficulties with transducing shear stress, there is no widely used shear measurement sensor. As such, we are currently developing a directionally sensitive pressure/shear sensor based on fiber optic technology. The pressure/shear sensor consists of an array of optical fibers lying in perpendicular rows and columns separated by elastomeric pads. A map of pressure and shear stress is constructed based on observed macro bending through the intensity attenuation from the physical deformation of two adjacent perpendicular fibers. The sensor has been shown to have low noise and responded linearly to applied loads. The smallest detectable force on each sensor element based on the current setup is ~0.1 lbs. (0.4N). The smallest area we have resolved in our mesh sensor is currently ~1 cm2.
Shear thickening and jamming in suspensions of different particle shapes

NASA Astrophysics Data System (ADS)

Brown, Eric; Zhang, Hanjun; Forman, Nicole; Betts, Douglas; Desimone, Joseph; Maynor, Benjamin; Jaeger, Heinrich

2012-02-01

We investigated the role of particle shape on shear thickening and jamming in densely packed suspensions. Various particle shapes were fabricated including rods of different aspect ratios and non-convex hooked rods. A rheometer was used to measure shear stress vs. shear rate for a wide range of packing fractions for each shape. Each suspensions exhibits qualitatively similar Discontinuous Shear Thickening, in which the logarithmic slope of the stress vs. shear rate has the same scaling for each convex shape and diverges at a critical packing fraction φc. The value of φc varies with particle shape, and coincides with the onset of a yield stress, a.k.a. the jamming transition. This suggests the jamming transition controls shear thickening, and the only effect of particle shape on steady state bulk rheology of convex particles is a shift of φc. Intriguingly, viscosity curves for non-convex particles do not collapse on the same set as convex particles, showing strong shear thickening over a wider range of packing fraction. Qualitative shape dependence was only found in steady state rheology when the system was confined to small gaps where large aspect ratio particle are forced to order.
The interaction of two spheres in a simple-shear flow of complex fluids

NASA Astrophysics Data System (ADS)

Firouznia, Mohammadhossein; Metzger, Bloen; Ovarlez, Guillaume; Hormozi, Sarah

2017-11-01

We study the interaction of two small freely-moving spheres in a linear flow field of Newtonian, shear thinning and yield stress fluids. We perform a series of experiments over a range of shear rates as well as different shear histories using an original apparatus and with the aid of conventional rheometry, Particle Image Velocimetry and Particle Tracking Velocimetry. Showing that the non-Newtonian nature of the suspending fluid strongly affects the shape of particle trajectories and the irreversibility. An important point is that non-Newtonian effects can be varied and unusual. Depending on the shear rate, nonideal shear thinning and yield stress suspending fluids might show elasticity that needs to be taken into account. The flow field around one particle is studied in different fluids when subjected to shear. Then using these results to explain the two particle interactions in a simple-shear flow we show how particle-particle contact and non-Newtonian behaviors result in relative trajectories with fore-aft asymmetry. Well-resolved velocity and stress fields around the particles are presented here. Finally, we discuss how the relative particle trajectories may affect the microstructure of complex suspensions and consequently the bulk rheology. NSF (Grant No. CBET-1554044-CAREER).
By activating matrix metalloproteinase-7, shear stress promotes chondrosarcoma cell motility, invasion and lung colonization

PubMed Central

Guan, Pei-Pei; Yu, Xin; Guo, Jian-Jun; Wang, Yue; Wang, Tao; Li, Jia-Yi; Konstantopoulos, Konstantinos; Wang, Zhan-You; Wang, Pu

2015-01-01

Interstitial fluid flow and associated shear stress are relevant mechanical signals in cartilage and bone (patho)physiology. However, their effects on chondrosarcoma cell motility, invasion and metastasis have yet to be delineated. Using human SW1353, HS.819.T and CH2879 chondrosarcoma cell lines as model systems, we found that fluid shear stress induces the accumulation of cyclic AMP (cAMP) and interleukin-1β (IL-1β), which in turn markedly enhance chondrosarcoma cell motility and invasion via the induction of matrix metalloproteinase-7 (MMP-7). Specifically, shear-induced cAMP and IL-1β activate PI3-K, ERK1/2 and p38 signaling pathways, which lead to the synthesis of MMP-7 via transactivating NF-κB and c-Jun in human chondrosarcoma cells. Importantly, MMP-7 upregulation in response to shear stress exposure has the ability to promote lung colonization of chondrosarcomas in vivo. These findings offer a better understanding of the mechanisms underlying MMP-7 activation in shear-stimulated chondrosarcoma cells, and provide insights on designing new therapeutic strategies to interfere with chondrosarcoma invasion and metastasis. PMID:25823818
In-Plane Shear Testing of Medium and High Modulus Woven Graphite Fiber Reinforced/Polyimide Composites

NASA Technical Reports Server (NTRS)

Gentz, M.; Armentrout, D.; Rupnowski, P.; Kumosa, L.; Shin, E.; Sutter, J. K.; Kumosa, M.

2004-01-01

Iosipescu shear tests were performed at room temperature and at 316 C (600 F) o woven composites with either M40J or M60J graphite fibers and PMR-II-50 polyimide resin matrix. The composites were tested as supplied and after thermo-cycling, with the thermo-cycled composites being tested under dry and wet conditions. Acoustic emission (AE) was monitored during the room and high temperature Iosipescu experiments. The shear stresses at the maximum loads and the shear stresses at the significant onset of AE were determined for the composites as function of temperature and conditioning. The combined effects of thermo-cycling and moisture on the strength and stiffness properties of the composites were evaluated. It was determined that the room and high temperature shear stresses at the maximum loads were unaffected by conditioning. However, at room temperature the significant onset of AE was affected by conditioning; the thermal conditioned wet specimens showed the highest shear stress at the onset of AE followed by thermal-conditioned and then as received specimens. Also, at igh temperature the significant onset of AE occurred in some specimens after the maximum load due to the viscoelastoplastic nature of the matrix material.
An Experimental Study on Normal Stress and Shear Rate Dependency of Basic Friction Coefficient in Dry and Wet Limestone Joints

NASA Astrophysics Data System (ADS)

Mehrishal, Seyedahmad; Sharifzadeh, Mostafa; Shahriar, Korosh; Song, Jae-Jon

2016-12-01

Among all parameters that affect the friction of rocks, variable normal stress and slip rate are the most important second-order parameters. The shear-rate- and normal-stress-dependent friction behavior of rock discontinuities may significantly influence the dynamic responses of rock mass. In this research, two limestone rock types, which were travertine and onyx marble with slickenside and grinded #80 surfaces, were prepared and CNL direct shear tests were performed on the joints under various shear conditions. The shearing rate varied from 0.1 to 50 mm/min under different normal stresses (from 2 to 30 % of UCS) in both dry and wet conditions. Experiments showed that the friction coefficient of slickensided and ground #80 surfaces of limestone increased with the increasing shear velocity and decreased with the increasing normal stress. Micro-asperity interlocking between ground #80 surfaces showed higher wear and an increase in friction coefficient ( µ) compared to slickensided surfaces. Slickensided samples with moist surfaces showed an increase in the coefficient of friction compared to dry surfaces; however, on ground #80 surfaces, the moisture decreased the coefficient of friction to a smaller value. Slickenside of limestone typically slides stably in a dry condition and by stick-slip on moist surfaces. The observed shear-rate- and normal-stress-dependent friction behavior can be explained by a similar framework to that of the adhesion theory of friction and a friction mechanism that involves the competition between microscopic dilatant slip and surface asperity deformation. The results have important implications for understanding the behavior of basic and residual friction coefficients of limestone rock surfaces.
Geological constraints on the mechanism of tectonic tremor

NASA Astrophysics Data System (ADS)

Kirkpatrick, J. D.

2016-12-01

Observations of tectonic tremor in a wide variety of tectonic settings suggest that transitional behavior involving contemporaneous shear fracture and aseismic creep transients occurs in many major faults. Seismological and geophysical data indicate shear failure on critically stressed faults, likely under low effective stress conditions, are consistent characteristics, even though rock types and grain scale deformation mechanisms vary at these different locations. Geological observations could add additional insight into the specific failure mechanisms if the structures that form during tremor episodes can be identified. Exhumed shear zones often contain folded, boudinaged and/or dynamically recrystallized veins that record cyclical fracture and viscous deformation representing mixed bulk rheology. Examples from a Cretaceous transpressional continental shear zone in the Sierra Nevada, CA, include quartz-filled veins meters to tens of meters long with millimeters to centimeters of shear offset that preferentially developed along foliation planes in a high strain zone. Ambient temperatures during deformation were 400-600°C, and opening mode vein orientations and abundance suggest fluid pressure was near lithostatic at times. The orientation and spatial distribution of the veins indicate they formed under differential stress large enough for shear failure with pore pressures sufficiently high for the rocks to be critically stressed along mechanically weak foliation planes. Bulk deformation of the surrounding rock was accommodated viscously by crystal plastic deformation mechanisms. The mode of fracturing and overall behavior of the system was controlled by the local competition between the rates of stress recovery following fracture and stress drop, and pore pressure build up. The inferred mixed rheology recorded by the veins is phenomenologically similar to tremor. These shear fractures, and the conditions of failure they record, could be comparable to the mechanism that produces tectonic tremor.
Determination of Residual Stress in Composite Materials Using Ultrasonic Waves

NASA Technical Reports Server (NTRS)

Rokhlin, S. I.

1997-01-01

The performance of high temperature composites can be significantly affected by the presence of residual stresses. These stresses arise during cooling processes from fabrication to room temperature due to mismatch of thermal expansion coefficients between matrix and fiber materials. This effect is especially pronounced in metal matrix and intermetallic composites. It can lead to plastic deformations, matrix cracking and fiber/matrix interface debonding. In this work the feasibility of ultrasonic techniques for residual stress assessment in composites is addressed. A novel technique for absolute stress determination in orthotropic materials from angular dependencies of ultrasonic velocities is described. The technique is applicable for determination of both applied and residual stresses and does not require calibration measurements on a reference sample. The important advantage of this method is that stress is determined simultaneously with stress-dependent elastic constants and is thus decoupled from the material texture. It is demonstrated that when the principal plane stress directions coincide with acoustical axes, the angular velocity data in the plane perpendicular to the stress plane may be used to determine both stress components. When the stress is off the acoustical axes, the shear and the difference of the normal stress components may be determined from the angular dependence of group velocities in the plane of stresses. Synthetic sets of experimental data corresponding to materials with different anisotropy and stress levels are used to check the applicability of the technique. The method is also verified experimentally. A high precision ultrasonic wave transmission technique is developed to measure angular dependence of ultrasonic velocities. Examples of stress determination from experimental velocity data are given. A method is presented for determination of velocities of ultrasonic waves propagating through the composite material with residual stresses. It is based on the generalized self-consistent multiple scattering model. Calculation results for longitudinal and shear ultrasonic wave velocities propagating perpendicular to the fibers direction in SCS-6/Ti composite with and without residual stresses are presented. They show that velocity changes due to presence of stresses are of order 1%.
Relating rheology to geometry in large-scale natural shear zones

NASA Astrophysics Data System (ADS)

Platt, John

2016-04-01

The geometry and width of the ductile roots of plate boundary scale faults are very poorly understood. Some field and geophysical data suggests widths of tens of km in the lower crust, possibly more in the upper mantle. Other observations suggest they are much narrower. Dip slip shear zones may flatten out and merge into zones of subhorizontal lower crustal or asthenospheric flow. The width of a ductile shear zone is simply related to relative velocity and strain rate. Strain rate is related to stress through the constitutive relationship. Can we constrain the stress, and do we understand the rheology of materials in ductile shear zones? A lot depends on how shear zones are initiated. If they are localized by pre-existing structures, width and/or rheology may be inherited, and we have too many variables. If shear zones are localized primarily by shear heating, initial shear stress has to be very high (> 1 GPa) to overcome conductive heat loss, and very large feedbacks (both positive and negative) make the system highly unstable. Microstructural weakening requires a minimum level of stress to cause deformation and damage in surrounding rock, thereby buffering the stress. Microstructural weakening leads to grain-size sensitive creep, for which we have constitutive laws, but these are complicated by phase mixing in polyphase materials, by viscous anisotropy, by hydration, and by changes in mineral assemblage. Here are some questions that need to be addressed. (1) If grain-size reduction by dynamic recrystallization results in a switch to grain-size sensitive creep (GSSC) in a stress-buffered shear zone, does dynamic recrystallization stop? Does grain growth set in? If grain-size is still controlled by dislocation processes, then the effective stress exponent for GSSC is 4-5, even though the dominant mechanism may be diffusion and/or grain-boundary sliding (GBS). (2) Is phase mixing in ultramylonites primarily a result of GBS + neighbour switching, creep cavitation and diffusion, or metamorphic reactions? (3) In two-phase / polyphase mixtures, does the strong phase generally form a load-bearing framework, favoring constant strain-rate (Voigt) bound behavior, or does the weak phase form through-going strain pathways, favoring constant stress (Reuss) bound behavior, or do the phases remain well mixed, favoring an intermediate behavior (e.g., Tullis et al model)? (4) How do we deal with the rheological effect of water? Is it simply an unconstrained variable in nature? Is the water fugacity model in flow laws adequate? (5) How can we better relate experimental results (often carried out at constant strain-rate, and not reaching microstructural steady state) to deformation in natural shear zones? Rheological observations on well-constrained natural shear zones are helping us answer some of these questions.
Role of endothelium sensitivity to shear stress in noradrenaline-induced constriction of feline femoral arterial bed under constant flow and constant pressure perfusions.

PubMed

Kartamyshev, Sergey P; Balashov, Sergey A; Melkumyants, Arthur M

2007-01-01

The effect of shear stress at the endothelium in the attenuation of the noradrenaline-induced constriction of the femoral vascular bed perfused at a constant blood flow was investigated in 16 anesthetized cats. It is known that the adrenergic vasoconstriction of the femoral vascular bed is considerably greater at a constant pressure perfusion than at a constant blood flow. This difference may depend on the ability of the endothelium to relax smooth muscle in response to an increase in wall shear stress. Since the shear stress is directly related to the blood flow and inversely related to the third power of vessel diameter, vasoconstriction at a constant blood flow increases the wall shear stress that is the stimulus for smooth muscle relaxation opposing constriction. On the other hand, at a constant perfusion pressure, vasoconstriction is accompanied by a decrease in flow rate, which prevents a wall shear stress increase. To reveal the effect of endothelial sensitivity to shear stress, we compared noradrenaline-induced changes in total and proximal arterial resistances during perfusion of the hind limb at a constant blood flow and at a constant pressure in vessels with intact and injured endothelium. We found that in the endothelium-intact bed the same concentration of noradrenaline at a constant flow caused an increase in overall vascular peripheral resistance that was half as large as at a constant perfusion pressure. This difference is mainly confined to the proximal arterial vessels (arteries and large arterioles) whose resistance at a constant flow increased only 0.19 +/- 0.03 times compared to that at a constant pressure. The removal of the endothelium only slightly increased constrictor responses at the perfusion under a constant pressure (noradrenaline-induced increases of both overall and proximal arterial resistance augmented by 12%), while the responses of the proximal vessels at a constant flow became 4.7 +/- 0.4 times greater than in the endothelium-intact bed. A selective blockage of endothelium sensitivity to shear stress using a glutaraldehyde dimer augmented the constrictor responses of the proximal vessels at a constant flow 4.6-fold (+/-0.3), but had no significant effect on the responses at a constant pressure. These results are consistent with the conclusion that the difference in constrictor responses at constant flow and pressure perfusions depends mainly on the smooth muscle relaxation caused by increased wall shear stress. Copyright (c) 2007 S. Karger AG, Basel.

Micromechanics of soil responses in cyclic simple shear tests

NASA Astrophysics Data System (ADS)

Cui, Liang; Bhattacharya, Subhamoy; Nikitas, George

2017-06-01

Offshore wind turbine (OWT) foundations are subjected to a combination of cyclic and dynamic loading arising from wind, wave, rotor and blade shadowing. Under cyclic loading, most soils change their characteristics including stiffness, which may cause the system natural frequency to approach the loading frequency and lead to unplanned resonance and system damage or even collapse. To investigate such changes and the underlying micromechanics, a series of cyclic simple shear tests were performed on the RedHill 110 sand with different shear strain amplitudes, vertical stresses and initial relative densities of soil. The test results showed that: (a) Vertical accumulated strain is proportional to the shear strain amplitude but inversely proportional to relative density of soil; (b) Shear modulus increases rapidly in the initial loading cycles and then the rate of increase diminishes and the shear modulus remains below an asymptote; (c) Shear modulus increases with increasing vertical stress and relative density, but decreasing with increasing strain amplitude. Coupled DEM simulations were performed using PFC2D to analyse the micromechanics underlying the cyclic behaviour of soils. Micromechanical parameters (e.g. fabric tensor, coordination number) were examined to explore the reasons for the various cyclic responses to different shear strain amplitudes or vertical stresses. Both coordination number and magnitude of fabric anisotropy contribute to the increasing shear modulus.
Quantitative Characterization of Shear-Induced Platelet Receptor Shedding: Glycoprotein Ibα, Glycoprotein VI, and Glycoprotein IIb/IIIa.

PubMed

Chen, Zengsheng; Koenig, Steven C; Slaughter, Mark S; Griffith, Bartley P; Wu, Zhongjun J

2017-11-07

The structural integrity of platelet receptors is essential for platelets to play the normal hemostatic function. The high non-physiologic shear stress (NPSS) commonly exists in blood-contacting medical devices and has been shown to cause platelet receptor shedding. The loss of platelet receptors may impair the normal hemostatic function of platelets. The aim of this study was to quantify NPSS-induced shedding of three key receptors on the platelet surface. Human blood was subjected to the matrix of well-defined shear stresses and exposure times, generated by using a custom-designed blood-shearing device. The expression of three key platelet receptors, glycoprotein (GP) Ibα, GPVI, and GPIIb/IIIa, in sheared blood was quantified using flow cytometry. The quantitative relationship between the loss of each of the three receptors on the platelet surface and shear condition (shear stress level and exposure time) was explored. It was found that these relationships followed well the power law functional form. The coefficients of the power law models for the shear-induced shedding of these platelet receptors were derived with coefficients of determination (R) of 0.77, 0.73, and 0.78, respectively. The power law models with these coefficients may be potentially used to predict the shear-induced platelet receptor shedding of human blood.
Microstructural and rheological evolution of calcite mylonites during shear zone thinning: Constraints from the Mount Irene shear zone, Fiordland, New Zealand

NASA Astrophysics Data System (ADS)

Negrini, Marianne; Smith, Steven A. F.; Scott, James M.; Tarling, Matthew S.

2018-01-01

Layers of calc-mylonite in the Mount Irene shear zone, Fiordland, New Zealand, show substantial variations in thickness due to deflection of the shear zone boundaries around wall rock asperities. In relatively thick parts (c. 2.6 m) of the shear zone, calcite porphyroclasts are internally strained, contain abundant subgrain boundaries and have a strong shape preferred orientation (SPO) and crystallographic preferred orientation (CPO), suggesting that deformation occurred mainly by dislocation creep involving subgrain-rotation recrystallization. In relatively thin parts (c. 1.5 m) of the shear zone, aggregates of fine-grained recrystallized calcite surrounding flattened porphyroclasts have a weak SPO and CPO, and contain polygonal calcite grains with low degrees of internal misorientation. The recrystallized aggregates also contain microstructures (e.g. grain quadruple junctions, randomized misorientation axes) similar to those reported for neighbor-switching processes during grain-boundary sliding. Comparison of subgrain sizes in the porphyroclasts to published grain-size differential-stress relationships indicates that stresses and strain rates were substantially higher in relatively thin parts of the shear zone. The primary microstructural response to higher stresses and strain rates was an increase in the amount of recrystallization to produce aggregates that deformed by grain-boundary sliding. However, even after the development of interconnected networks of recrystallized grains, dislocation creep by subgrain-rotation recrystallization continued to occur within porphyroclasts. This behavior suggests that the bulk rheology of shear zones undergoing thinning and thickening can be controlled by concomitant grain-size insensitive and grain-size sensitive mechanisms. Overall, our observations show that shear zone thickness variations at constant P-T can result in highly variable stresses and strain rates, which in turn modifies microstructure, deformation mechanism and shear zone rheology.
In-plane and Interlaminar Shear Strength of a Unidirectional Hi-nicalon Fiber-reinforced Celsian Matrix Composite

NASA Technical Reports Server (NTRS)

Uenal, O.; Bansal, N. P.

2000-01-01

In-plane and interlaminar shear strength of a unidirectional SiC fiber-reinforced (BaSr)Al2Si2O8 celsian composite were measured by the double-notch shear test method between room temperature and 1200 C. The interlaminar shear strength was lower than the in-plane shear strength at all temperatures. Stress analysis, using finite element modeling, indicated that shear stress concentration was not responsible for the observed difference in strength. Instead, the difference in layer architecture and thus, the favorable alignment of fiber-rich layers with the shear plane in the interlaminar specimens appears to be the reason for the low strength of this composite. A rapid decrease in strength was observed with temperature due to softening of the glassy phase in the material.
Flow-dependent regulation of endothelial nitric oxide synthase: role of protein kinases

NASA Technical Reports Server (NTRS)

Boo, Yong Chool; Jo, Hanjoong

2003-01-01

Vascular endothelial cells are directly and continuously exposed to fluid shear stress generated by blood flow. Shear stress regulates endothelial structure and function by controlling expression of mechanosensitive genes and production of vasoactive factors such as nitric oxide (NO). Though it is well known that shear stress stimulates NO production from endothelial nitric oxide synthase (eNOS), the underlying molecular mechanisms remain unclear and controversial. Shear-induced production of NO involves Ca2+/calmodulin-independent mechanisms, including phosphorylation of eNOS at several sites and its interaction with other proteins, including caveolin and heat shock protein-90. There have been conflicting results as to which protein kinases-protein kinase A, protein kinase B (Akt), other Ser/Thr protein kinases, or tyrosine kinases-are responsible for shear-dependent eNOS regulation. The functional significance of each phosphorylation site is still unclear. We have attempted to summarize the current status of understanding in shear-dependent eNOS regulation.
Cloning the Gravity and Shear Stress Related Genes from MG-63 Cells by Subtracting Hybridization

NASA Astrophysics Data System (ADS)

Zhang, Shu; Dai, Zhong-quan; Wang, Bing; Cao, Xin-sheng; Li, Ying-hui; Sun, Xi-qing

2008-06-01

Background The purpose of the present study was to clone the gravity and shear stress related genes from osteoblast-like human osteosarcoma MG-63 cells by subtractive hybridization. Method MG-63 cells were divided into two groups (1G group and simulated microgravity group). After cultured for 60 h in two different gravitational environments, two groups of MG-63 cells were treated with 1.5Pa fluid shear stress (FSS) for 60 min, respectively. The total RNA in cells was isolated. The gravity and shear stress related genes were cloned by subtractive hybridization. Result 200 clones were gained. 30 positive clones were selected using PCR method based on the primers of vector and sequenced. The obtained sequences were analyzed by blast. changes of 17 sequences were confirmed by RT-PCR and these genes are related to cell proliferation, cell differentiation, protein synthesis, signal transduction and apoptosis. 5 unknown genes related to gravity and shear stress were found. Conclusion In this part of our study, our result indicates that simulated microgravity may change the activities of MG-63 cells by inducing the functional alterations of specific genes.
Oscillatory motion based measurement method and sensor for measuring wall shear stress due to fluid flow

DOEpatents

Armstrong, William D [Laramie, WY; Naughton, Jonathan [Laramie, WY; Lindberg, William R [Laramie, WY

2008-09-02

A shear stress sensor for measuring fluid wall shear stress on a test surface is provided. The wall shear stress sensor is comprised of an active sensing surface and a sensor body. An elastic mechanism mounted between the active sensing surface and the sensor body allows movement between the active sensing surface and the sensor body. A driving mechanism forces the shear stress sensor to oscillate. A measuring mechanism measures displacement of the active sensing surface relative to the sensor body. The sensor may be operated under periodic excitation where changes in the nature of the fluid properties or the fluid flow over the sensor measurably changes the amplitude or phase of the motion of the active sensing surface, or changes the force and power required from a control system in order to maintain constant motion. The device may be operated under non-periodic excitation where changes in the nature of the fluid properties or the fluid flow over the sensor change the transient motion of the active sensor surface or change the force and power required from a control system to maintain a specified transient motion of the active sensor surface.
Extremely high wall-shear stress events in a turbulent boundary layer

NASA Astrophysics Data System (ADS)

Pan, Chong; Kwon, Yongseok

2018-04-01

The present work studies the fluctuating characteristics of the streamwise wall-shear stress in a DNS of a turbulent boundary layer at Re τ =1500 from a structural view. The two-dimensional field of the fluctuating friction velocity u‧ τ (x,z) is decomposed into the large- and small-scale components via a recently proposed scale separation algorithm, Quasi-bivariate Variational Mode Decomposition (QB-VMD). Both components are found to be dominated by streak-like structures, which can be regarded as the wall signature of the inner-layer streaks and the outer-layer LSMs, respectively. Extreme positive/negative wall-shear stress fluctuation events are detected in the large-scale component. The former’s occurrence frequency is nearly one order of magnitude higher than the latter; therefore, they contribute a significant portion of the long tail of the wall-shear stress distribution. Both two-point correlations and conditional averages show that these extreme positive wall-shear stress events are embedded in the large-scale positive u‧ τ streaks. They seem to be formed by near-wall ‘splatting’ process, which are related to strong finger-like sweeping (Q4) events originated from the outer-layer positive LSMs.
The impact of wall shear stress and pressure drop on the stability of the atherosclerotic plaque.

PubMed

Li, Zhi-Yong; Taviani, Valentina; Gillard, Jonathan H

2008-01-01

Rupture of vulnerable atheromatous plaque in the carotid and coronary arteries often leads to stroke and heart attack respectively. The mechanism of blood flow and plaque rupture in stenotic arteries is still not fully understood. A three dimensional rigid wall model was solved under steady state conditions and unsteady conditions by assuming a time-varying inlet velocity profile to investigate the relative importance of axial forces and pressure drops in arteries with asymmetric stenosis. Flow-structure interactions were investigated for the same geometry and the results were compared with those retrieved with the corresponding 2D cross-section structural models. The Navier-Stokes equations were used as the governing equations for the fluid. The tube wall was assumed hyperelastic, homogeneous, isotropic and incompressible. The analysis showed that the three dimensional behavior of velocity, pressure and wall shear stress is in general very different from that predicted by cross-section models. Pressure drop across the stenosis was found to be much higher than shear stress. Therefore, pressure may be the more important mechanical trigger for plaque rupture other than shear stress, although shear stress is closely related to plaque formation and progression.
Application of mean wall shear stress boundary condition to complex turbulent flows using a wall-modeled large eddy simulation

NASA Astrophysics Data System (ADS)

Cho, Minjeong; Lee, Jungil; Choi, Haecheon

2012-11-01

The mean wall shear stress boundary condition was successfully applied to turbulent channel and boundary flows using large eddy simulation without resolving near-wall region (see Lee, Cho & Choi in this book of abstracts). In the present study, we apply this boundary condition to more complex flows where flow separation and redeveloping flow exist. As a test problem, we consider flow over a backward-facing step at Reh = 22860 based on the step height. Turbulent boundary layer flow at the inlet (Reθ = 1050) is obtained using inflow generation technique by Lund et al. (1998) but with wall shear stress boundary condition. First, we prescribe the mean wall shear stress distribution obtained from DNS (Kim, 2011, Ph.D. Thesis, Stanford U.) as the boundary condition of present simulation. Here we give no-slip boundary condition at flow-reversal region. The present results are in good agreements with the flow statistics by DNS. Currently, a dynamic approach of obtaining mean wall shear stress based on the log-law is being applied to the flow having flow separation and its results will be shown in the presentation. Supported by the WCU and NRF programs.
Development of a MEMS dual-axis differential capacitance floating element shear stress sensor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barnard, Casey; Griffin, Benjamin

A single-axis MEMS wall shear stress sensor with differential capacitive transduction method is produced. Using a synchronous modulation and demodulation interface circuit, the system is capable of making real time measurements of both mean and fluctuating wall shear stress. A sensitivity of 3.44 mV/Pa is achieved, with linearity in response demonstrated up to testing limit of 2 Pa. Minimum detectable signals of 340 μPa at 100 Hz and 120 μPa at 1 kHz are indicated, with a resonance of 3.5 kHz. Multiple full scale wind tunnel tests are performed, producing spectral measurements of turbulent boundary layers in wind speeds rangingmore » up to 0.5 Ma (18 Pa of mean wall shear stress). The compact packaging allows for minimally invasive installation, and has proven relatively robust over multiple testing events. Temperature sensitivity, likely due to poor CTE matching of packaged materials, is an ongoing concern being addressed. These successes are being directly leveraged into a development plan for a dual-axis wall shear stress sensor, capable of producing true vector estimates at the wall.« less
Nanomechanics of slip avalanches in amorphous plasticity

NASA Astrophysics Data System (ADS)

Cao, Penghui; Dahmen, Karin A.; Kushima, Akihiro; Wright, Wendelin J.; Park, Harold S.; Short, Michael P.; Yip, Sidney

2018-05-01

Discrete stress relaxations (slip avalanches) in a model metallic glass under uniaxial compression are studied using a metadynamics algorithm for molecular simulation at experimental strain rates. The onset of yielding is observed at the first major stress drop, accompanied, upon analysis, by the formation of a single localized shear band region spanning the entire system. During the elastic response prior to yielding, low concentrations of shear transformation deformation events appear intermittently and spatially uncorrelated. During serrated flow following yielding, small stress drops occur interspersed between large drops. The simulation results point to a threshold value of stress dissipation as a characteristic feature separating major and minor avalanches consistent with mean-field modeling analysis and mechanical testing experiments. We further interpret this behavior to be a consequence of a nonlinear interplay of two prevailing mechanisms of amorphous plasticity, thermally activated atomic diffusion and stress-induced shear transformations, originally proposed by Spaepen and Argon, respectively. Probing the atomistic processes at widely separate strain rates gives insight to different modes of shear band formation: percolation of shear transformations versus crack-like propagation. Additionally a focus on crossover avalanche size has implications for nanomechanical modeling of spatially and temporally heterogeneous dynamics.
Diffractive Optic Fluid Shear Stress Sensor

NASA Technical Reports Server (NTRS)

Wilson, D.; Scalf, J.; Forouhar, S.; Muller, R.; Taugwalder, F.; Gharib, M.; Fourguette, D.; Modarress, D.

2000-01-01

Light scattering off particles flowing through a two-slit interference pattern can be used to measure the shear stress of the fluid. We have designed and fabricated a miniature diffractive optic sensor based on this principle.
Some constraints on levels of shear stress in the crust from observations and theory.

USGS Publications Warehouse

McGarr, A.

1980-01-01

In situ stress determinations in North America, southern Africa, and Australia indicate that on the average the maximum shear stress increases linearly with depth to at least 5.1 km measured in soft rock, such as shale and sandstone, and to 3.7 km in hard rock, including granite and quartzite. Regression lines fitted to the data yield gradients of 3.8 MPa/km and 6.6 MPa/km for soft and hard rock, respectively. Generally, the maximum shear stress in compressional states of stress for which the least principal stress is oriented near vertically is substantially greater than in extensional stress regimes, with the greatest principal stress in a vertical direction. The equations of equilibrium and compatibility can be used to provide functional constrains on the state of stress. If the stress is assumed to vary only with depth z in a given region, then all nonzero components must have the form A + Bz, where A and B are constants which generally differ for the various components. - Author
Shear thickening in concentrated suspensions: phenomenology, mechanisms and relations to jamming

NASA Astrophysics Data System (ADS)

Brown, Eric; Jaeger, Heinrich M.

2014-04-01

Shear thickening is a type of non-Newtonian behavior in which the stress required to shear a fluid increases faster than linearly with shear rate. Many concentrated suspensions of particles exhibit an especially dramatic version, known as Discontinuous Shear Thickening (DST), in which the stress suddenly jumps with increasing shear rate and produces solid-like behavior. The best known example of such counter-intuitive response to applied stresses occurs in mixtures of cornstarch in water. Over the last several years, this shear-induced solid-like behavior together with a variety of other unusual fluid phenomena has generated considerable interest in the physics of densely packed suspensions. In this review, we discuss the common physical properties of systems exhibiting shear thickening, and different mechanisms and models proposed to describe it. We then suggest how these mechanisms may be related and generalized, and propose a general phase diagram for shear thickening systems. We also discuss how recent work has related the physics of shear thickening to that of granular materials and jammed systems. Since DST is described by models that require only simple generic interactions between particles, we outline the broader context of other concentrated many-particle systems such as foams and emulsions, and explain why DST is restricted to the parameter regime of hard-particle suspensions. Finally, we discuss some of the outstanding problems and emerging opportunities.
Compact forced simple-shear sample for studying shear localization in materials

DOE PAGES

Gray, George Thompson; Vecchio, K. S.; Livescu, Veronica

2015-11-06

In this paper, a new specimen geometry, the compact forced-simple-shear specimen (CFSS), has been developed as a means to achieve simple shear testing of materials over a range of temperatures and strain rates. The stress and strain state in the gage section is designed to produce essentially “pure” simple shear, mode II in-plane shear, in a compact-sample geometry. The 2-D plane of shear can be directly aligned along specified directional aspects of a material's microstructure of interest; i.e., systematic shear loading parallel, at 45°, and orthogonal to anisotropic microstructural features in a material such as the pancake-shaped grains typical inmore » many rolled structural metals, or to specified directions in fiber-reinforced composites. Finally, the shear-stress shear-strain response and the damage evolution parallel and orthogonal to the pancake grain morphology in 7039-Al are shown to vary significantly as a function of orientation to the microstructure.« less
A sliding plate microgap rheometer for the simultaneous measurement of shear stress and first normal stress difference

NASA Astrophysics Data System (ADS)

Baik, Seung Jae; Moldenaers, Paula; Clasen, Christian

2011-03-01

A new generation of the "flexure-based microgap rheometer" (the N-FMR) has been developed which is also capable of measuring, in addition to the shear stress, the first normal stress difference of micrometer thin fluid films. This microgap rheometer with a translation system based on compound spring flexures measures the rheological properties of microliter samples of complex fluids confined in a plane couette configuration with gap distances of h = 1-400 μm up to shear rates of dot γ = 3000 s-1. Feed back loop controlled precise positioning of the shearing surfaces with response times <1 ms enables to control the parallelism within 1.5 μrad and to maintain the gap distance within 20 nm. This precise gap control minimizes squeeze flow effects and allows therefore to measure the first normal stress difference N1 of the thin film down to a micrometer gap distance, with a lower limit of {{N_1 }/{dot γ }} = 9.375 × 10^{ - 11} {η/{h^2 }} that depends on the shear viscosity η and the squared inverse gap. Structural development of complex fluids in the confinement can be visualized by using a beam splitter on the shearing surface and a long working distance microscope. In summary, this new instrument allows to investigate the confinement dependent rheological and morphological evolution of micrometer thin films.
Time-frequency analyses of fluid-solid interaction under sinusoidal translational shear deformation of the viscoelastic rat cerebrum

NASA Astrophysics Data System (ADS)

Leahy, Lauren N.; Haslach, Henry W.

2018-02-01

During normal extracellular fluid (ECF) flow in the brain glymphatic system or during pathological flow induced by trauma resulting from impacts and blast waves, ECF-solid matter interactions result from sinusoidal shear waves in the brain and cranial arterial tissue, both heterogeneous biological tissues with high fluid content. The flow in the glymphatic system is known to be forced by pulsations of the cranial arteries at about 1 Hz. The experimental shear stress response to sinusoidal translational shear deformation at 1 Hz and 25% strain amplitude and either 0% or 33% compression is compared for rat cerebrum and bovine aortic tissue. Time-frequency analyses aim to correlate the shear stress signal frequency components over time with the behavior of brain tissue constituents to identify the physical source of the shear nonlinear viscoelastic response. Discrete fast Fourier transformation analysis and the novel application to the shear stress signal of harmonic wavelet decomposition both show significant 1 Hz and 3 Hz components. The 3 Hz component in brain tissue, whose magnitude is much larger than in aortic tissue, may result from interstitial fluid induced drag forces. The harmonic wavelet decomposition locates 3 Hz harmonics whose magnitudes decrease on subsequent cycles perhaps because of bond breaking that results in easier fluid movement. Both tissues exhibit transient shear stress softening similar to the Mullins effect in rubber. The form of a new mathematical model for the drag force produced by ECF-solid matter interactions captures the third harmonic seen experimentally.
Static and kinetic friction of granite at high normal stress

USGS Publications Warehouse

Byerlee, J.D.

1970-01-01

Frictional sliding on ground surfaces of granite, angle of sliding planes 30?? and 45??, was investigated as a function of confining pressure. Over the normal stress range of 2-12 kb, the static frictional shear stress ??s follows the relationship ??s = 0??5 + 0?? ??n and the kinetic frictional shear stress ??k was calculated to be ??k = 0??25 + 0??47 ??n. ?? 1970.
Dependency of the injection induced seismicity b-value on the stress state of existing fractures

NASA Astrophysics Data System (ADS)

Mukuhira, Y.; Fehler, M. C.; Ito, T.; Asanuma, H.; Häring, M. O.

2017-12-01

The Gutenberg-Richter distribution of earthquake is a power law relationship and it holds for laboratory scale earthquakes (acoustic emission) to subduction zone earthquakes as well as induced seismicity. The gradient of the power law is known as the b-value, which can be considered the ratio of the number of the larger earthquakes to small ones. Larger earthquakes are often observed in low b-value regions, or alternatively a b-value reduction has been observed before some main shocks. Some authors have argued that b-value is negatively correlated with differential stress level. Therefore, a b-value anomaly found in time-space analysis may be used for detection of an area of stress concentration and used for earthquake prediction or hazard risk assessment. In the field of induced seismicity where b-value reduction has also been observed, the physical mechanism of b-value reduction has not been understood well. Since induced seismicity related with fluid injection usually occurs at depths around 1000 5000 m, a significant tectonic mechanism to cause a stress concentration during a short time of hydraulic stimulation might not be expected. We used borehole analysis and focal mechanism information to investigate the stress state on the existing fractures that caused induced seismicity. Then we divide the catalog into the groups with varying normalized shear stress threshold and estimated the b-value. We found that b-value for the events that occurred along higher shear stress fractures were significantly lower (figure 1a) than those from the moderate/lower shear stress fractures (figure 1b). Thus, b-value dependency on the shear stress can be observed for induced seismicity on a reservoir scale. Therefore, we propose that the reason for the observed b-value reductions in induced seismicity on a reservoir scale is the events that occur along higher shear stress fractures. Supposing that the earthquakes occurs along well-orientated fractures, the b-value dependence on differential stress can be translated to dependence on increasing shear stress. Thus, our observations about b-value are consistent with the conventional interpretations of b-value.

Whole-body heat stress and exercise stimulate the appearance of platelet microvesicles in plasma with limited influence of vascular shear stress.

PubMed

Wilhelm, Eurico N; González-Alonso, José; Chiesa, Scott T; Trangmar, Steven J; Kalsi, Kameljit K; Rakobowchuk, Mark

2017-11-01

Intense, large muscle mass exercise increases circulating microvesicles, but our understanding of microvesicle dynamics and mechanisms inducing their release remains limited. However, increased vascular shear stress is generally thought to be involved. Here, we manipulated exercise-independent and exercise-dependent shear stress using systemic heat stress with localized single-leg cooling (low shear) followed by single-leg knee extensor exercise with the cooled or heated leg (Study 1, n = 8) and whole-body passive heat stress followed by cycling (Study 2, n = 8). We quantified femoral artery shear rates (SRs) and arterial and venous platelet microvesicles (PMV-CD41 + ) and endothelial microvesicles (EMV-CD62E + ). In Study 1, mild passive heat stress while one leg remained cooled did not affect [microvesicle] ( P ≥ 0.05). Single-leg knee extensor exercise increased active leg SRs by ~12-fold and increased arterial and venous [PMVs] by two- to threefold, even in the nonexercising contralateral leg ( P < 0.05). In Study 2, moderate whole-body passive heat stress increased arterial [PMV] compared with baseline (mean±SE, from 19.9 ± 1.5 to 35.5 ± 5.4 PMV . μ L -1. 10 3 , P < 0.05), and cycling with heat stress increased [PMV] further in the venous circulation (from 27.5 ± 2.2 at baseline to 57.5 ± 7.2 PMV . μ L -1. 10 3 during cycling with heat stress, P < 0.05), with a tendency for increased appearance of PMV across exercising limbs. Taken together, these findings demonstrate that whole-body heat stress may increase arterial [PMV], and intense exercise engaging either large or small muscle mass promote PMV formation locally and systemically, with no influence upon [EMV]. Local shear stress, however, does not appear to be the major stimulus modulating PMV formation in healthy humans. © 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.
Transform push, oblique subduction resistance, and intraplate stress of the Juan de Fuca plate

USGS Publications Warehouse

Wang, K.; He, J.; Davis, E.E.

1997-01-01

The Juan de Fuca plate is a small oceanic plate between the Pacific and North America plates. In the southernmost region, referred to as the Gorda deformation zone, the maximum compressive stress a, constrained by earthquake focal mechanisms is N-S. Off Oregon, and possibly off Washington, NW trending left-lateral faults cutting the Juan de Fuca plate indicate a a, in a NE-SW to E-W direction. The magnitude of differential stress increases from north to south; this is inferred from the plastic yielding and distribution of earthquakes throughout the Gorda deformation zone. To understand how tectonic forces determine the stress field of the Juan de Fuca plate, we have modeled the intraplate stress using both elastic and elastic-perfectly plastic plane-stress finite element models. We conclude that the right-lateral shear motion of the Pacific and North America plates is primarily responsible for the stress pattern of the Juan de Fuca plate. The most important roles are played by a compressional force normal to the Mendocino transform fault, a result of the northward push by the Pacific plate and a horizontal resistance operating against the northward, or margin-parallel, component of oblique subduction. Margin-parallel subduction resistance results in large N-S compression in the Gorda deformation zone because the force is integrated over the full length of the Cascadia subduction zone. The Mendocino transform fault serves as a strong buttress that is very weak in shear but capable of transmitting large strike-normal compressive stresses. Internal failure of the Gorda deformation zone potentially places limits on the magnitude of the fault-normal stresses being transmitted and correspondingly on the magnitude of strike-parallel subduction resistance. Transform faults and oblique subduction zones in other parts of the world can be expected to transmit and create stresses in the same manner. Copyright 1997 by the American Geophysical Union.
Mode selective generation of guided waves by systematic optimization of the interfacial shear stress profile

NASA Astrophysics Data System (ADS)

Yazdanpanah Moghadam, Peyman; Quaegebeur, Nicolas; Masson, Patrice

2015-01-01

Piezoelectric transducers are commonly used in structural health monitoring systems to generate and measure ultrasonic guided waves (GWs) by applying interfacial shear and normal stresses to the host structure. In most cases, in order to perform damage detection, advanced signal processing techniques are required, since a minimum of two dispersive modes are propagating in the host structure. In this paper, a systematic approach for mode selection is proposed by optimizing the interfacial shear stress profile applied to the host structure, representing the first step of a global optimization of selective mode actuator design. This approach has the potential of reducing the complexity of signal processing tools as the number of propagating modes could be reduced. Using the superposition principle, an analytical method is first developed for GWs excitation by a finite number of uniform segments, each contributing with a given elementary shear stress profile. Based on this, cost functions are defined in order to minimize the undesired modes and amplify the selected mode and the optimization problem is solved with a parallel genetic algorithm optimization framework. Advantages of this method over more conventional transducers tuning approaches are that (1) the shear stress can be explicitly optimized to both excite one mode and suppress other undesired modes, (2) the size of the excitation area is not constrained and mode-selective excitation is still possible even if excitation width is smaller than all excited wavelengths, and (3) the selectivity is increased and the bandwidth extended. The complexity of the optimal shear stress profile obtained is shown considering two cost functions with various optimal excitation widths and number of segments. Results illustrate that the desired mode (A0 or S0) can be excited dominantly over other modes up to a wave power ratio of 1010 using an optimal shear stress profile.
Marginal bed load transport in a gravel bed stream, Sagehen Creek, California

USGS Publications Warehouse

Andrews, E.D.

1994-01-01

Marginal bed load transport describes the condition when relatively few bed particles are moving at any time. Bed particles resting in the shallowest bed pockets will move when the dimensionless shear stress т* exceeds a value of about 0.020. As т* increases, the number of bed particles moving increases. Significant motion of bed particles, i.e., when a substantial fraction of the bed particles are moving, occurs when т* exceeds a value of about 0.060. Thus marginal bed load transport occurs over the domain 0.020 < т* < 0.060. Marginal bed load transport rates and associated hydraulic characteristics of Sagehen Creek, a small mountain gravel bed stream, were measured on 55 days at discharges ranging from slightly less than one half of the bank-full discharge to more than 4 times the bank-full discharge. Dimensionless shear stress varied from 0.032 to 0.042, and bed particles as large as the 80th percentile of the bed surface were transported. The relation between reference dimensionless shear stress and relative particle protrusion for Sagehen Creek was determined by varying т*ri to obtain the best fit of the Parker bed load function to the measured transport rates. During the period of record (water years 1954–1991), the mean annual quantity of bed load transported past the Sagehen Creek gage was 24.7 tons. Forty-seven percent of all bed load transported during the 38 years of record occurred in just 6 years. During 10 of the 38 years of record, essentially no bed load was transported. The median diameter of bed load was 26 mm, compared to 58 mm in the surface bed material.
Experiments on Pool-riffle Sequences with Multi-fractional Sediment Bed During Floods

NASA Astrophysics Data System (ADS)

Rodriguez, J. F.; Vahidi, E.; Bayat, E.; de Almeida, G. A. M.; Saco, P. M.

2017-12-01

The morphodynamics of pools and riffles has been the subject of research for over a century and has more recently attracted intense attention for their central role in providing habitat diversity conditions, both in terms of flow and substrate. Initial efforts to explain the long-term stability of the pool-riffle (PR) sequences (often referred to as self-maintenance) focused almost exclusively on cross sectional flow characteristics (either average or near bed velocity or shear stress), using episodic shifts in higher shear stress or velocities from riffles to pools during floods (i.e. reversal conditions) as an indication of the long-term self-maintenance of the structures.. However, less attention has been paid to the interactions of flow unsteadiness, sediment supply and sedimentological contrasts as the drivers for maintaining PR sequences. Here we investigate these effects through laboratory experiments on a scaled-down PR sequence of an existing gravel bed river. Froude similitude and equality of Shields' number were applied to scale one- to four-year recurrence flood events and sediment size distributions, respectively. We conducted experiments with different hydrographs and different sedimentological conditions. In each experiment we continuously measured velocities and shear stresses (using acoustic velocity profilers) bed levels (using a bed profiler) and bed grain size distribution (using an automatic digital technique on the painted bed sediments) during the hydrographs. Our results show that the most important factors for self-maintenance were the sediment bed composition, the level of infilling of the pool and the sediment supply grainsize distribution. These results highlight the need to consider the time varying sedimentological characteristics of a PR sequence to assess its capacity for self-maintenance.
Mechanism of the influence of hydrodynamics on Microcystis aeruginosa, a dominant bloom species in reservoirs.

PubMed

Song, Yang; Zhang, Ling-Lei; Li, Jia; Chen, Min; Zhang, Yao-Wen

2018-04-26

Hydrodynamic conditions play a key role in algal blooms, which have become an increasing threat to aquatic environments, especially reservoirs. Microcystis aeruginosa is a dominant species in algal blooms in reservoirs and releases large amounts of algal toxins during algal bloom events. The algal growth characteristics and the corresponding mechanism of the influence of hydrodynamic conditions were explored using custom hydraulic rotating devices. The long-term experimental results were as follows: (1) a moderate flow velocity increased the algal growth rate and prolonged algal lifetime relative to static water; (2) moderate water turbulence promoted energy metabolism and nutrient absorbance in algal cells; (3) moderate shear stress reduced oxidation levels in algal cells and improved algal cell morphology; (4) under hydrodynamic treatment, algal cell deformation was confirmed by scanning electron microscopy (SEM), and a high shear stress of 0.0104 Pa induced by a flow of 0.5 m/s may have destroyed cell morphology and disturbed reactive oxygen species (ROS) metabolism; (5) algal cell morphology evaluation (including circle ratio, eccentricity, diameter increasing rate, and deformation rate) was established; (6) based on algal growth status and specific effects, five independent intervals (including 'positive-promotion', 'middle-promotion', 'negative-promotion', 'transition', and 'inhibition') and the hydrodynamic threshold system (including flow velocity, turbulent dissipation, and shear stress) were established; and (7) for M. aeruginosa, the optimum flow velocity was 0.24 m/s, and the static-equivalent flow velocity was 0.47 m/s. These results provide a basic summary of the hydrodynamic effects on algal growth and a useful reference for the control of M. aeruginosa blooms in reservoirs. Copyright © 2018 Elsevier B.V. All rights reserved.
Effects of shear load on frictional healing

NASA Astrophysics Data System (ADS)

Ryan, K. L.; Marone, C.

2014-12-01

During the seismic cycle of repeated earthquake failure, faults regain strength in a process known as frictional healing. Laboratory studies have played a central role in illuminating the processes of frictional healing and fault re-strengthening. These studies have also provided the foundation for laboratory-derived friction constitutive laws, which have been used extensively to model earthquake dynamics. We conducted laboratory experiments to assess the affect of shear load on frictional healing. Frictional healing is quantified during slide-hold-slide (SHS) tests, which serve as a simple laboratory analog for the seismic cycle in which earthquakes (slide) are followed by interseismic quiescence (hold). We studied bare surfaces of Westerly granite and layers of Westerly granite gouge (thickness of 3 mm) at normal stresses from 4-25 MPa, relative humidity of 40-60%, and loading and unloading velocities of 10-300 μm/s. During the hold period of SHS tests, shear stress on the sample was partially removed to investigate the effects of shear load on frictional healing and to isolate time- and slip-dependent effects on fault healing. Preliminary results are consistent with existing works and indicate that frictional healing increases with the logarithm of hold time and decreases with normalized shear stress τ/τf during the hold. During SHS tests with hold periods of 100 seconds, healing values ranged from (0.013-0.014) for τ/τf = 1 to (0.059-0.063) for τ/τf = 0, where τ is the shear stress during the hold period and τf is the shear stress during steady frictional sliding. Experiments on bare rock surfaces and with natural and synthetic fault gouge materials are in progress. Conventional SHS tests (i.e. τ/τf = 1) are adequately described by the rate and state friction laws. However, previous experiments in granular quartz suggest that zero-stress SHS tests are not well characterized by either the Dieterich or Ruina state evolution laws. We are investigating the processes that produce shear stress dependent frictional healing, alternate forms of the state evolution law, and comparing results for friction of bare rock surfaces and granular fault gouge.
Fan-structure wave as a source of earthquake instability

NASA Astrophysics Data System (ADS)

Tarasov, Boris

2015-04-01

Today frictional shear resistance along pre-existing faults is considered to be the lower limit on rock shear strength at confined compression corresponding to the seismogenic layer. This determines the lithospheric strength and the primary earthquake mechanism associated with frictional stick-slip instability on pre-existing faults. This paper introduces a recently identified shear rupture mechanism providing a paradoxical feature of hard rocks - the possibility of shear rupture propagation through the highly confined intact rock mass at shear stress levels significantly less than frictional strength. In the new mechanism the rock failure, associated with consecutive creation of small slabs (known as 'domino-blocks') from the intact rock in the rupture tip, is driven by a fan-shaped domino structure representing the rupture head. The fan-head combines such unique features as: extremely low shear resistance (below the frictional strength), self-sustaining stress intensification in the rupture tip (providing easy formation of new domino-blocks), and self-unbalancing conditions in the fan-head (making the failure process inevitably spontaneous and violent). An important feature of the fan-mechanism is the fact that for the initial formation of the fan-structure an enhanced local shear stress is required, however, after completion of the fan-structure it can propagate as a dynamic wave through intact rock mass at shear stresses below the frictional strength. Paradoxically low shear strength of pristine rocks provided by the fan-mechanism determines the lower limit of the lithospheric strength and favours the generation of new faults in pristine rocks in preference to frictional stick-slip instability along pre-existing faults. The new approach reveals an alternative role of pre-existing faults in earthquake activity: they represent local stress concentrates in pristine rock adjoining the fault where special conditions for the fan-mechanism nucleation are created, while further dynamic propagation of the new fault (earthquake) occurs at low field stresses even below the frictional strength. However, the proximity of the pre-existing discontinuities to the area of instability caused by the fan mechanism creates the illusion of stick-slip instability on the pre-existing faults, thus concealing the real situation.
Breaking symmetry in non-planar bifurcations: distribution of flow and wall shear stress.

PubMed

Lu, Yiling; Lu, Xiyun; Zhuang, Lixian; Wang, Wen

2002-01-01

Non-planarity in blood vessels is known to influence arterial flows and wall shear stress. To gain insight, computational fluid dynamics (CFD) has been used to investigate effects of curvature and out-of-plane geometry on the distribution of fluid flows and wall shear stresses in a hypothetical non-planar bifurcation. Three-dimensional Navier-Stokes equations for a steady state Newtonian fluid were solved numerically using a finite element method. Non-planarity in one of the two daughter vessels is found to deflect flow from the inner wall of the vessel to the outer wall and to cause changes in the distribution of wall shear stresses. Results from this study agree to experimental observations and CFD simulations in the literature, and support the view that non-planarity in blood vessels is a factor with important haemodynamic significance and may play a key role in vascular biology and pathophysiology.
Enhanced t -3/2 long-time tail for the stress-stress time correlation function

NASA Astrophysics Data System (ADS)

Evans, Denis J.

1980-01-01

Nonequilibrium molecular dynamics is used to calculate the spectrum of shear viscosity for a Lennard-Jones fluid. The calculated zero-frequency shear viscosity agrees well with experimental argon results for the two state points considered. The low-frequency behavior of shear viscosity is dominated by an ω 1/2 cusp. Analysis of the form of this cusp reveals that the stress-stress time correlation function exhibits a t -3/2 "long-time tail." It is shown that for the state points studied, the amplitude of this long-time tail is between 12 and 150 times larger than what has been predicted theoretically. If the low-frequency results are truly asymptotic, they imply that the cross and potential contributions to the Kubo-Green integrand for shear viscosity exhibit a t -3/2 long-time tail. This result contradicts the established theory of such processes.
Response of hot element flush wall gauges in oscillating laminar flow

NASA Technical Reports Server (NTRS)

Giddings, T. A.; Cook, W. J.

1986-01-01

The time dependent response characteristics of flush-mounted hot element gauges used as instruments to measure wall shear stress in unsteady periodic air flows were investigated. The study was initiated because anomalous results were obtained from the gauges in oscillating turbulent flows for the phase relation of the wall shear stress variation, indicating possible gauge response problems. Flat plate laminar oscillating turbulent flows characterized by a mean free stream velocity with a superposed sinusoidal variation were performed. Laminar rather than turbulent flows were studied, because a numerical solution for the phase angle between the free stream velocity and the wall shear stress variation that is known to be correct can be obtained. The focus is on comparing the phase angle indicated by the hot element gauges with corresponding numerical prediction for the phase angle, since agreement would indicate that the hot element gauges faithfully follow the true wall shear stress variation.
The Effects of Hemodynamic Shear Stress on Stemness of Acute Myelogenous Leukemia (AML)

NASA Astrophysics Data System (ADS)

Raddatz, Andrew; Triantafillu, Ursula; Kim, Yonghyun (John)

2015-11-01

Cancer stem cells (CSCs) have recently been identified as the root cause of tumors generated from cancer cell populations. This is because these CSCs are drug-resistant and have the ability to self-renew and differentiate. Current methods of culturing CSCs require much time and money, so cancer cell culture protocols, which maximize yield of CSCs are needed. It was hypothesized that the quantity of Acute myelogenous leukemia stem cells (LSCs) would increase after applying shear stress to the leukemia cells based on previous studies with breast cancer in bioreactors. The shear stress was applied by pumping the cells through narrow tubing to mimic the in vivo bloodstream environment. In support of the hypothesis, shear stress was found to increase the amount of LSCs in a given leukemia population. This work was supported by NSF REU Site Award 1358991.
Atomistic Simulation of Interstitial Dislocation Loop Evolution under Applied Stresses in BCC Iron

DOE Office of Scientific and Technical Information (OSTI.GOV)

Long, Xue Hao; Wang, Dong; Setyawan, Wahyu

Evolution of an interstitial 1/2⟨111⟩ dislocation loop under tensile, shear, and torsion stresses is studied with molecular statics method. Under a tensile stress, the dependence of ultimate tensile strength on size of loop is calculated. The formation of small shear loops around the initial prismatic loop is confirmed as an intermediate state to form the final dislocation network. Under a shear stress, the rotation of a loop is observed not only by a change of the habit plane but also through a transformation between a shear and a prismatic loop. Under torsion, a perfect BCC crystal may undergo a BCCmore » to FCC or BCC to HCP transformation. The present work indicates that a 1/2⟨111⟩ loop can delay these transformations, resulting in the formation of micro-crack on the surface.« less
The Fluid Mechanics of a Wavy-Wall Bioreactor

NASA Astrophysics Data System (ADS)

Sucosky, Philippe; Bilgen, Bahar; Aleem, Alexander; Neitzel, Paul; Barabino, Gilda

2004-11-01

Bioreactors are devices used for the production of mammalian tissue in vitro. Although mixing has been shown to stimulate the growth of cartilage constructs, high shear-stress levels can damage the cells. In order to enhance mixing while minimizing shear, a wavy-wall bioreactor (WWB) featuring a sinusoidal internal profile has been designed. The turbulent hydrodynamic environment produced in this device is investigated experimentally using particle-image velocimetry. A model bioreactor made of acrylic and filled with an index-matching solution of zinc iodide is used to compensate for the refraction of light at the walls. The flow observed in different planes is shown to be periodic, spatially dependent, and dominated by mean-shear rather than Reynolds stresses in the vicinity of constructs. Finally, a comparison between the mean-shear stresses obtained in the WWB and in a standard spinner flask reveals similar stress levels near the construct walls.
PI16 is a shear stress and inflammation-regulated inhibitor of MMP2

PubMed Central

Hazell, Georgina G. J.; Peachey, Alasdair M. G.; Teasdale, Jack E.; Sala-Newby, Graciela B.; Angelini, Gianni D.; Newby, Andrew C.; White, Stephen J.

2016-01-01

Raised endothelial shear stress is protective against atherosclerosis but such protection may be lost at sites of inflammation. We found that four splice variants of the peptidase inhibitor 16 (PI16) mRNA are among the most highly shear stress regulated transcripts in human coronary artery endothelial cells (HCAECs), in vitro but that expression is reduced by inflammatory mediators TNFα and IL-1β. Immunohistochemistry demonstrated that PI16 is expressed in human coronary endothelium and in a subset of neointimal cells and medial smooth muscle cells. Adenovirus-mediated PI16 overexpression inhibits HCAEC migration and secreted matrix metalloproteinase (MMP) activity. Moreover, PI16 inhibits MMP2 in part by binding an exposed peptide loop above the active site. Our results imply that, at high endothelial shear stress, PI16 contributes to inhibition of protease activity; protection that can be reversed during inflammation. PMID:27996045
Bioprocess Forces and Their Impact on Cell Behavior: Implications for Bone Regeneration Therapy

PubMed Central

Brindley, David; Moorthy, Kishaani; Lee, Jae-Ho; Mason, Chris; Kim, Hae-Won; Wall, Ivan

2011-01-01

Bioprocess forces such as shear stress experienced during routine cell culture are considered to be harmful to cells. However, the impact of physical forces on cell behavior is an area of growing interest within the tissue engineering community, and it is widely acknowledged that mechanical stimulation including shear stress can enhance osteogenic differentiation. This paper considers the effects of bioprocess shear stress on cell responses such as survival and proliferation in several contexts, including suspension-adapted cells used for recombinant protein and monoclonal antibody manufacture, adherent cells for therapy in suspension, and adherent cells attached to their growth substrates. The enhanced osteogenic differentiation that fluid flow shear stress is widely found to induce is discussed, along with the tissue engineering of mineralized tissue using perfusion bioreactors. Recent evidence that bioprocess forces produced during capillary transfer or pipetting of cell suspensions can enhance osteogenic responses is also discussed. PMID:21904661
Phase transformations in nanograin materials under high pressure and plastic shear: nanoscale mechanisms.

PubMed

Levitas, Valery I; Javanbakht, Mahdi

2014-01-07

There are two main challenges in the discovery of new high pressure phases (HPPs) and transforming this discovery into technologies: finding conditions to synthesize new HPPs and finding ways to reduce the phase transformation (PT) pressure to an economically reasonable level. Based on the results of pressure-shear experiments in the rotational diamond anvil cell (RDAC), superposition of plastic shear on high pressure is a promising way to resolve these problems. However, physical mechanisms behind these phenomena are not yet understood. Here, we elucidate generic mechanisms of coupled nucleation and evolution of dislocation and HPP structures in the nanograin material under pressure and shear utilizing the developed advanced phase field approach (PFA). Dislocations are generated at the grain boundaries and are densely piled up near them, creating a strong concentrator of the stress tensor. Averaged shear stress is essentially larger in the nanograin material due to grain boundary strengthening. This leads to the increase in the local thermodynamic driving force for PT, which allows one to significantly reduce the applied pressure. For all cases, the applied pressure is 3-20 times lower than the PT pressure and 2-12.5 times smaller than the phase equilibrium pressure. Interaction between nuclei leads sometimes to their coalescence and growth of the HPP away from stress concentrators. Plasticity plays a dual role: in addition to creating stress concentrators, it may relax stresses at other concentrators, thus competing with PT. Some ways to optimize the loading parameters have been found that lead to methods for controlling PT. Since such a local stress tensor with high shear stress component cannot be created without plastic deformations, this may lead to new transformation paths and phases, which are hidden during pressure induced PTs.
A Two-Axis Direct Fluid Shear Stress Sensor

NASA Technical Reports Server (NTRS)

Adcock, Edward E.; Scott, Michael A.; Bajikar, Sateesh S.

2010-01-01

This innovation is a miniature or micro sized semiconductor sensor design that provides two axis direct non-intrusive measurement of skin friction or wall shear stress in fluid flow. The sensor is fabricated by micro-electro-mechanical system (MEMS) technology, enabling small size and low cost reproductions. The sensors have been fabricated by utilizing MEMS fabrication processes to bond a sensing element wafer to a fluid coupling wafer. This layering technique provides for an out of plane dimension that is on the same order of length as the inplane dimensions. The sensor design has the following characteristics: a shear force collecting plate with dimensions that can be tailored to various application specific requirements such as spatial resolution, temporal resolution and shear force range and resolution. This plate is located coplanar to both the sensor body and flow boundary, and is connected to a dual axis gimbal structure by a connecting column or lever arm. The dual axis gimbal structure has torsional hinges with embedded piezoresistive torsional strain gauges which provide a voltage output that is correlated to the applied shear stress (and excitation current) on force collection plate that is located on the flow boundary surface (hence the transduction method). This combination of design elements create a force concentration and resolution structure that enables the generation of a large stress on the strain gauge from the small shear stress on the flow boundary wall. This design as well as the use of back side electrical contacts establishes a non-intrusive method to quantitatively measure the shear force vector on aerodynamic bodies.
Dynamics of shear-induced ATP release from red blood cells.

PubMed

Wan, Jiandi; Ristenpart, William D; Stone, Howard A

2008-10-28

Adenosine triphosphate (ATP) is a regulatory molecule for many cell functions, both for intracellular and, perhaps less well known, extracellular functions. An important example of the latter involves red blood cells (RBCs), which help regulate blood pressure by releasing ATP as a vasodilatory signaling molecule in response to the increased shear stress inside arterial constrictions. Although shear-induced ATP release has been observed widely and is believed to be triggered by deformation of the cell membrane, the underlying mechanosensing mechanism inside RBCs is still controversial. Here, we use an in vitro microfluidic approach to investigate the dynamics of shear-induced ATP release from human RBCs with millisecond resolution. We demonstrate that there is a sizable delay time between the onset of increased shear stress and the release of ATP. This response time decreases with shear stress, but surprisingly does not depend significantly on membrane rigidity. Furthermore, we show that even though the RBCs deform significantly in short constrictions (duration of increased stress <3 ms), no measurable ATP is released. This critical timescale is commensurate with a characteristic membrane relaxation time determined from observations of the cell deformation by using high-speed video. Taken together our results suggest a model wherein the retraction of the spectrin-actin cytoskeleton network triggers the mechanosensitive ATP release and a shear-dependent membrane viscosity controls the rate of release.
Evolution of Friction, Wear, and Seismic Radiation Along Experimental Bi-material Faults

NASA Astrophysics Data System (ADS)

Carpenter, B. M.; Zu, X.; Shadoan, T.; Self, A.; Reches, Z.

2017-12-01

Faults are commonly composed by rocks of different lithologies and mechanical properties that are positioned against one another by fault slip; such faults are referred to as bimaterial-faults (BF). We investigate the mechanical behavior, wear production, and seismic radiation of BF via laboratory experiments on a rotary shear apparatus. In the experiments, two rock blocks of dissimilar or similar lithology are sheared against each other. We used contrasting rock pairs of a stiff, igneous block (diorite, granite, or gabbro) against a more compliant, sedimentary block (sandstone, limestone, or dolomite). The cylindrical blocks have a ring-shaped contact, and are loaded under conditions of constant normal stress and shear velocity. Fault behavior was monitored with stress, velocity and dilation sensors. Acoustic activity is monitored with four 3D accelerometers mounted at 2 cm distance from the experimental fault. These sensors can measure accelerations up to 500 g, and their full waveform output is recorded at 1MHz for periods up to 14 sec. Our preliminary results indicate that the bi-material nature of the fault has a strong affect on slip initiation, wear evolution, and acoustic emission activity. In terms of wear, we observe enhanced wear in experiments with a sandstone block sheared against a gabbro or limestone block. Experiments with a limestone or sandstone block produced distinct slickenline striations. Further, significant differences appeared in the number and amplitude of acoustic events depending on the bi-material setting and slip-distance. A gabbro-gabbro fault showed a decrease in both amplitude and number of acoustic events with increasing slip. Conversely, a gabbro-limestone fault showed a decrease in the number of events, but an increase in average event amplitude. Ongoing work focuses on advanced characterization of mechanical, dynamic weakening, and acoustic, frequency content, parameters.

Normal stresses in semiflexible polymer hydrogels

NASA Astrophysics Data System (ADS)

Vahabi, M.; Vos, Bart E.; de Cagny, Henri C. G.; Bonn, Daniel; Koenderink, Gijsje H.; MacKintosh, F. C.

2018-03-01

Biopolymer gels such as fibrin and collagen networks are known to develop tensile axial stress when subject to torsion. This negative normal stress is opposite to the classical Poynting effect observed for most elastic solids including synthetic polymer gels, where torsion provokes a positive normal stress. As shown recently, this anomalous behavior in fibrin gels depends on the open, porous network structure of biopolymer gels, which facilitates interstitial fluid flow during shear and can be described by a phenomenological two-fluid model with viscous coupling between network and solvent. Here we extend this model and develop a microscopic model for the individual diagonal components of the stress tensor that determine the axial response of semiflexible polymer hydrogels. This microscopic model predicts that the magnitude of these stress components depends inversely on the characteristic strain for the onset of nonlinear shear stress, which we confirm experimentally by shear rheometry on fibrin gels. Moreover, our model predicts a transient behavior of the normal stress, which is in excellent agreement with the full time-dependent normal stress we measure.
Imaging shear stress distribution and evaluating the stress concentration factor of the human eye

NASA Astrophysics Data System (ADS)

Joseph Antony, S.

2015-03-01

Healthy eyes are vital for a better quality of human life. Historically, for man-made materials, scientists and engineers use stress concentration factors to characterise the effects of structural non-homogeneities on their mechanical strength. However, such information is scarce for the human eye. Here we present the shear stress distribution profiles of a healthy human cornea surface in vivo using photo-stress analysis tomography, which is a non-intrusive and non-X-ray based method. The corneal birefringent retardation measured here is comparable to that of previous studies. Using this, we derive eye stress concentration factors and the directional alignment of major principal stress on the surface of the cornea. Similar to thermometers being used for monitoring the general health in humans, this report provides a foundation to characterise the shear stress carrying capacity of the cornea, and a potential bench mark for validating theoretical modelling of stresses in the human eye in future.
The stress response system of proteins: Implications for bioreactor scaleup

NASA Technical Reports Server (NTRS)

Goochee, Charles F.

1988-01-01

Animal cells face a variety of environmental stresses in large scale bioreactors, including periodic variations in shear stress and dissolved oxygen concentration. Diagnostic techniques were developed for identifying the particular sources of environmental stresses for animal cells in a given bioreactor configuration. The mechanisms by which cells cope with such stresses was examined. The individual concentrations and synthesis rates of hundreds of intracellular proteins are affected by the extracellular environment (medium composition, dissolved oxygen concentration, ph, and level of surface shear stress). Techniques are currently being developed for quantifying the synthesis rates and concentrations of the intracellular proteins which are most sensitive to environmental stress. Previous research has demonstrated that a particular set of stress response proteins are synthesized by mammalian cells in response to temperature fluctuations, dissolved oxygen deprivation, and glucose deprivation. Recently, it was demonstrated that exposure of human kidney cells to high shear stress results in expression of a completely distinct set of intracellular proteins.
Direct numerical simulations of premixed autoignition in compressible uniformly-sheared turbulence

NASA Astrophysics Data System (ADS)

Towery, Colin; Darragh, Ryan; Poludnenko, Alexei; Hamlington, Peter

2017-11-01

High-speed combustion systems, such as scramjet engines, operate at high temperatures and pressures, extremely short combustor residence times, very high rates of shear stress, and intense turbulent mixing. As a result, the reacting flow can be premixed and have highly-compressible turbulence fluctuations. We investigate the effects of compressible turbulence on the ignition delay time, heat-release-rate (HRR) intermittency, and mode of autoignition of premixed Hydrogen-air fuel in uniformly-sheared turbulence using new three-dimensional direct numerical simulations with a multi-step chemistry mechanism. We analyze autoignition in both the Eulerian and Lagrangian reference frames at eight different turbulence Mach numbers, Mat , spanning the quasi-isentropic, linear thermodynamic, and nonlinear compressibility regimes, with eddy shocklets appearing in the nonlinear regime. Results are compared to our previous study of premixed autoignition in isotropic turbulence at the same Mat and with a single-step reaction mechanism. This previous study found large decreases in delay times and large increases in HRR intermittency between the linear and nonlinear compressibility regimes and that detonation waves could form in both regimes.
Evaluation of Uncertainty in Bedload Transport Estimates in a Southern Appalachian Stream

NASA Astrophysics Data System (ADS)

Schwartz, J. S.

2016-12-01

Capacity estimates of bed-material transport rates are generally derived using empirical formulae as a function of bed material gradation and composition, and hydraulic shear stress. Various field techniques may be used to sample and characterize bed material gradation; some techniques assume the existing bar material is representative of that in transport. Other methods use Helly-Smith samplers, pit traps, and net traps. Very few large, complete cross-section pit traps fully instrumented to collect continuous bedload transport have been constructed, and none in the eastern United States to our knowledge. A fully-instrumented bedload collection station was constructed on Little Turkey Creek (LTC) in Farragut, Tennessee. The aim of the research was to characterize bed material transport during stormflows for a southern Appalachian stream in the Ridge and Valley Providence. Bedload transport data from LTC was compared with classic datasets including Oak Creek (Oregon), East Fork River (Wyoming), and Clearwater and Snake rivers (Idaho). In addition, data were evaluated to assess the potential accuracy of both calibrated and uncalibrated bedload transport models using bedload transport data from LTC. Uncalibrated models were assessed with regard to their estimated range of uncertainty according to Monte Carlo uncertainty analyses. Models calibrated using reference shear values determined according to station measurements are evaluated in the same manner. Finally, models calibrated using the small scale, short-term, low rate bedload sampling techniques promoted in the literature for the spreadsheet based Bedload Assessment in Gravel-bedded Streams (BAGS) software for determining the reference shear stress are compared to results of both uncalibrated models and those calibrated using data from the bedload station. This research supports design and construction of dynamically stable alluvial stream restoration projects where stream channels are largely dependent on reach-scale hydraulic geometry that provides a long-term balance between bed-material sediment supply and transport capacity.
Form drag in rivers due to small-scale natural topographic features: 1. Regular sequences

USGS Publications Warehouse

Kean, J.W.; Smith, J.D.

2006-01-01

Small-scale topographic features are commonly found on the boundaries of natural rivers, streams, and floodplains. A simple method for determining the form drag on these features is presented, and the results of this model are compared to laboratory measurements. The roughness elements are modeled as Gaussian-shaped features defined in terms of three parameters: a protrusion height, H; a streamwise length scale, ??; and a spacing between crests, ??. This shape is shown to be a good approximation to a wide variety of natural topographic bank features. The form drag on an individual roughness element embedded in a series of identical elements is determined using the drag coefficient of the individual element and a reference velocity that includes the effects of roughness elements further upstream. In addition to calculating the drag on each element, the model determines the spatially averaged total stress, skin friction stress, and roughness height of the boundary. The effects of bank roughness on patterns of velocity and boundary shear stress are determined by combining the form drag model with a channel flow model. The combined model shows that drag on small-scale topographic features substantially alters the near-bank flow field. These methods can be used to improve predictions of flow resistance in rivers and to form the basis for fully predictive (no empirically adjusted parameters) channel flow models. They also provide a foundation for calculating the near-bank boundary shear stress fields necessary for determining rates of sediment transport and lateral erosion.
A test of the double-shearing model of flow for granular materials

USGS Publications Warehouse

Savage, J.C.; Lockner, D.A.

1997-01-01

The double-shearing model of flow attributes plastic deformation in granular materials to cooperative slip on conjugate Coulomb shears (surfaces upon which the Coulomb yield condition is satisfied). The strict formulation of the double-shearing model then requires that the slip lines in the material coincide with the Coulomb shears. Three different experiments that approximate simple shear deformation in granular media appear to be inconsistent with this strict formulation. For example, the orientation of the principal stress axes in a layer of sand driven in steady, simple shear was measured subject to the assumption that the Coulomb failure criterion was satisfied on some surfaces (orientation unspecified) within the sand layer. The orientation of the inferred principal compressive axis was then compared with the orientations predicted by the double-shearing model. The strict formulation of the model [Spencer, 1982] predicts that the principal stress axes should rotate in a sense opposite to that inferred from the experiments. A less restrictive formulation of the double-shearing model by de Josselin de Jong [1971] does not completely specify the solution but does prescribe limits on the possible orientations of the principal stress axes. The orientations of the principal compression axis inferred from the experiments are probably within those limits. An elastoplastic formulation of the double-shearing model [de Josselin de Jong, 1988] is reasonably consistent with the experiments, although quantitative agreement was not attained. Thus we conclude that the double-shearing model may be a viable law to describe deformation of granular materials, but the macroscopic slip surfaces will not in general coincide with the Coulomb shears.
Nuclear envelope proteins Nesprin2 and LaminA regulate proliferation and apoptosis of vascular endothelial cells in response to shear stress.

PubMed

Han, Yue; Wang, Lu; Yao, Qing-Ping; Zhang, Ping; Liu, Bo; Wang, Guo-Liang; Shen, Bao-Rong; Cheng, Binbin; Wang, Yingxiao; Jiang, Zong-Lai; Qi, Ying-Xin

2015-05-01

The dysfunction of vascular endothelial cells (ECs) influenced by flow shear stress is crucial for vascular remodeling. However, the roles of nuclear envelope (NE) proteins in shear stress-induced EC dysfunction are still unknown. Our results indicated that, compared with normal shear stress (NSS), low shear stress (LowSS) suppressed the expression of two types of NE proteins, Nesprin2 and LaminA, and increased the proliferation and apoptosis of ECs. Targeted small interfering RNA (siRNA) and gene overexpression plasmid transfection revealed that Nesprin2 and LaminA participate in the regulation of EC proliferation and apoptosis. A protein/DNA array was further used to detect the activation of transcription factors in ECs following transfection with target siRNAs and overexpression plasmids. The regulation of AP-2 and TFIID mediated by Nesprin2 and the activation of Stat-1, Stat-3, Stat-5 and Stat-6 by LaminA were verified under shear stress. Furthermore, using Ingenuity Pathway Analysis software and real-time RT-PCR, the effects of Nesprin2 or LaminA on the downstream target genes of AP-2, TFIID, and Stat-1, Stat-3, Stat-5 and Stat-6, respectively, were investigated under LowSS. Our study has revealed that NE proteins are novel mechano-sensitive molecules in ECs. LowSS suppresses the expression of Nesprin2 and LaminA, which may subsequently modulate the activation of important transcription factors and eventually lead to EC dysfunction. Copyright © 2015 Elsevier B.V. All rights reserved.
Bed Surface Adjustments to Spatially Variable Flow in Low Relative Submergence Regimes

NASA Astrophysics Data System (ADS)

Monsalve, A.; Yager, E. M.

2017-11-01

In mountainous rivers, large relatively immobile grains partly control the local and reach-averaged flow hydraulics and sediment fluxes. When the flow depth is similar to the size of these grains (low relative submergence), heterogeneous flow structures and plunging flow cause spatial distributions of bed surface elevations, textures, and sedimentation rates. To explore how the bed surface responds to these flow variations we conducted a set of experiments in which we varied the relative submergence of staggered hemispheres (simulated large boulders) between runs. All experiments had the same average sediment transport capacity, upstream sediment supply, and initial bed thickness and grain size distribution. We combined our laboratory measurements with a 3-D flow model to obtain the detailed flow structure around the hemispheres. The local bed shear stress field displayed substantial variability and controlled the bed load transport rates and direction in which sediment moved. The divergence in bed shear stress caused by the hemispheres promoted size-selective bed load deposition, which formed patches of coarse sediment upstream of the hemisphere. Sediment deposition caused a decrease in local bed shear stress, which combined with the coarser grain size, enhanced the stability of this patch. The region downstream of the hemispheres was largely controlled by a recirculation zone and had little to no change in grain size, bed elevation, and bed shear stress. The formation, development, and stability of sediment patches in mountain streams is controlled by the bed shear stress divergence and magnitude and direction of the local bed shear stress field.
The Need for a Shear Stress Calibration Standard

NASA Technical Reports Server (NTRS)

Scott, Michael A.

2004-01-01

By surveying current research of various micro-electro mechanical systems (MEMS) shear stress sensor development efforts we illustrate the wide variety of methods used to test and characterize these sensors. The different methods of testing these sensors make comparison of results difficult in some cases, and also this comparison is further complicated by the different formats used in reporting the results of these tests. The fact that making these comparisons can be so difficult at times clearly illustrates a need for standardized testing and reporting methodologies. This need indicates that the development of a national or international standard for the calibration of MEMS shear stress sensors should be undertaken. As a first step towards the development of this standard, two types of devices are compared and contrasted. The first type device is a laminar flow channel with two different versions considered: the first built with standard manufacturing techniques and the second with advanced precision manufacturing techniques. The second type of device is a new concept for creating a known shear stress consisting of a rotating wheel with the sensor mounted tangentially to the rim and positioned in close proximity to the rim. The shear stress generated by the flow at the sensor position is simply tau = (mu)r(omega)/h, where mu is the viscosity of the ambient gas, r the wheel radius, omega the angular velocity of the wheel, and h the width of the gap between the wheel rim and the sensor. Additionally, issues related to the development of a standard for shear stress calibration are identified and discussed.
Quantification and significance of fluid shear stress field in biaxial cell stretching device.

PubMed

Thompson, Mark S; Abercrombie, Stuart R; Ott, Claus-Eric; Bieler, Friederike H; Duda, Georg N; Ventikos, Yiannis

2011-07-01

A widely used commercially available system for the investigation of mechanosensitivity applies a biaxial strain field to cells cultured on a compliant silicone substrate membrane stretched over a central post. As well as intended substrate strain, this device also provides a fluid flow environment for the cultured cells. In order to interpret the relevance of experiments using this device to the in vivo and clinical situation, it is essential to characterise both substrate and fluid environments. While previous work has detailed the substrate strain, the fluid shear stresses, to which bone cells are known to be sensitive, are unknown. Therefore, a fluid structure interaction computational fluid dynamics model was constructed, incorporating a finite element technique capable of capturing the contact between the post and the silicone substrate membrane, to the underside of which the pump control pressure was applied. Flow verification experiments using 10-μm-diameter fluorescent microspheres were carried out. Fluid shear stress increased approximately linearly with radius along the on-post substrate membrane, with peak values located close to the post edge. Changes in stimulation frequency and culture medium viscosity effected proportional changes in the magnitude of the fluid shear stress (peak fluid shear stresses varied in the range 0.09-3.5 Pa), with minor effects on temporal and spatial distribution. Good agreement was obtained between predicted and measured radial flow patterns. These results suggest a reinterpretation of previous data obtained using this device to include the potential for a strong role of fluid shear stress in mechanosensitivity.
Pulmonary blood flow and pulmonary hypertension: Is the pulmonary circulation flowophobic or flowophilic?

PubMed Central

Kulik, Thomas J.

2012-01-01

Increased pulmonary blood flow (PBF) is widely thought to provoke pulmonary vascular obstructive disease (PVO), but the impact of wall shear stress in the lung is actually poorly defined. We examined information from patients having cardiac lesions which impact the pulmonary circulation in distinct ways, as well as experimental studies, asking how altered hemodynamics impact the risk of developing PVO. Our results are as follows: (1) with atrial septal defect (ASD; increased PBF but low PAP), shear stress may be increased but there is little tendency to develop PVO; (2) with normal PBF but increased pulmonary vascular resistance (PVR; mitral valve disease) shear stress may also be increased but risk of PVO still low; (3) with high PVR and PBF (e.g., large ventricular septal defect), wall shear stress is markedly increased and the likelihood of developing PVO is much higher than with high PBF or PAP only; and (4) with ASD, experimental and clinical observations suggest that increased PBF plus another stimulus (e.g., endothelial inflammation) may be required for PVO. We conclude that modestly increased wall shear stress (e.g., ASD) infrequently provokes PVO, and likely requires other factors to be harmful. Likewise, increased PAP seldom causes PVO. Markedly increased wall shear stress may greatly increase the likelihood of PVO, but we cannot discriminate its effect from the combined effects of increased PAP and PBF. Finally, the age of onset of increased PAP may critically impact the risk of PVO. Some implications of these observations for future investigations are discussed. PMID:23130101
Tidal asymmetry and variability of bed shear stress and sediment bed flux at a site in San Francisco Bay, USA

USGS Publications Warehouse

Brennan, Matthew L.; Schoellhamer, David H.; Burau, Jon R.; Monismith, Stephen G.; Winterwerp, J.C.; Kranenburg, C.

2002-01-01

The relationship between sediment bed flux and bed shear stress during a pair of field experiments in a partially stratified estuary is examined in this paper. Time series of flow velocity, vertical density profiles, and suspended sediment concentration were measured continuously throughout the water column and intensely within 1 meter of the bed. These time series were analyzed to determine bed shear stress, vertical turbulent sediment flux, and mass of sediment suspended in the water column. Resuspension, as inferred from near-bed measurements of vertical turbulent sediment flux, was flood dominant, in accordance with the flood-dominant bed shear stress. Bathymetry-induced residual flow, gravitational circulation, and ebb tide salinity stratification contributed to the flood dominance. In addition to this flow-induced asymmetry, the erodibility of the sediment appears to increase during the first 2 hours of flood tide. Tidal asymmetry in bed shear stress and erodibility help explain an estuarine turbidity maximum that is present during flood tide but absent during ebb tide. Because horizontal advection was insignificant during most of the observation periods, the change in bed mass can be estimated from changes in the total suspended sediment mass. The square wave shape of the bed mass time series indicates that suspended sediment rapidly deposited in an unconsolidated or concentrated benthic suspension layer at slack tides and instantly resuspended when the shear stress became sufficiently large during a subsequent tide. The variability of bed mass associated with the spring/neap cycle (about 60 mg/cm2) is similar to that associated with the semidiurnal tidal cycle.
F-actin and microtubule suspensions as indeterminate fluids.

PubMed

Buxbaum, R E; Dennerll, T; Weiss, S; Heidemann, S R

1987-03-20

The viscosity of F-actin and microtubule suspensions has been measured as a function of shear rate with a Weissenberg rheogoniometer. At shear rates of less than 1.0 per second the viscosity of suspensions of these two structural proteins is inversely proportional to shear rate. These results are consistent with previous in vivo measurements of the viscosity of cytoplasm. This power law implies that shear stress is independent of shear rate; that is, shear stress is a constant at all shear rates less than 1.0 per second. Thus the flow profile of these fluids is indeterminate, or nearly so. This flow property may explain several aspects of intracellular motility in living cells. Possible explanations for this flow property are based on a recent model for semidilute suspensions of rigid rods or a classical friction model for liquid crystals.
Assessment of turbulent viscous stress using ICOSA 4D Flow MRI for prediction of hemodynamic blood damage

NASA Astrophysics Data System (ADS)

Ha, Hojin; Lantz, Jonas; Haraldsson, Henrik; Casas, Belen; Ziegler, Magnus; Karlsson, Matts; Saloner, David; Dyverfeldt, Petter; Ebbers, Tino

2016-12-01

Flow-induced blood damage plays an important role in determining the hemodynamic impact of abnormal blood flow, but quantifying of these effects, which are dominated by shear stresses in highly fluctuating turbulent flow, has not been feasible. This study evaluated the novel application of turbulence tensor measurements using simulated 4D Flow MRI data with six-directional velocity encoding for assessing hemodynamic stresses and corresponding blood damage index (BDI) in stenotic turbulent blood flow. The results showed that 4D Flow MRI underestimates the maximum principal shear stress of laminar viscous stress (PLVS), and overestimates the maximum principal shear stress of Reynolds stress (PRSS) with increasing voxel size. PLVS and PRSS were also overestimated by about 1.2 and 4.6 times at medium signal to noise ratio (SNR) = 20. In contrast, the square sum of the turbulent viscous shear stress (TVSS), which is used for blood damage index (BDI) estimation, was not severely affected by SNR and voxel size. The square sum of TVSS and the BDI at SNR >20 were underestimated by less than 1% and 10%, respectively. In conclusion, this study demonstrated the feasibility of 4D Flow MRI based quantification of TVSS and BDI which are closely linked to blood damage.
Analysis of bonded joints. [shear stress and stress-strain diagrams

NASA Technical Reports Server (NTRS)

Srinivas, S.

1975-01-01

A refined elastic analysis of bonded joints which accounts for transverse shear deformation and transverse normal stress was developed to obtain the stresses and displacements in the adherends and in the bond. The displacements were expanded in terms of polynomials in the thicknesswise coordinate; the coefficients of these polynomials were functions of the axial coordinate. The stress distribution was obtained in terms of these coefficients by using strain-displacement and stress-strain relations. The governing differential equations were obtained by integrating the equations of equilibrium, and were solved. The boundary conditions (interface or support) were satisfied to complete the analysis. Single-lap, flush, and double-lap joints were analyzed, along with the effects of adhesive properties, plate thicknesses, material properties, and plate taper on maximum peel and shear stresses in the bond. The results obtained by using the thin-beam analysis available in the literature were compared with the results obtained by using the refined analysis. In general, thin-beam analysis yielded reasonably accurate results, but in certain cases the errors were high. Numerical investigations showed that the maximum peel and shear stresses in the bond can be reduced by (1) using a combination of flexible and stiff bonds, (2) using stiffer lap plates, and (3) tapering the plates.
Baseline tensile tests of composite materials for LDEF (Long Duration Exposure Facility) exposure

NASA Technical Reports Server (NTRS)

Witte, William G.

1987-01-01

Tensile specimens of five graphite fiber reinforced composite materials were tested at room temperature to provide baseline data for similar specimens exposed to the space environment in low-Earth orbit on the NASA Long Duration Exposure Facility. All specimens were 4-ply (+ or - 45 deg)s layups; at least five replicate specimens were tested for each parameter evaluated. Three epoxy-matrix materials and two polysulfone-matrix materials, several fiber volume fractions, and two sizes of specimen were evaluated. Stress-strain and Poisson's ratio-stress curves, ultimate stress, strain at failure, secant modulus at 0.004 strain, inplane shear stress-strain curves, and unidirectional shear modulus at .004 shear strain are presented.
Investigation of high-speed free shear flows using improved pressure-strain correlated Reynolds stress turbulence model

NASA Technical Reports Server (NTRS)

Tiwari, S. N.; Lakshmanan, B.

1993-01-01

A high-speed shear layer is studied using compressibility corrected Reynolds stress turbulence model which employs newly developed model for pressure-strain correlation. MacCormack explicit prediction-corrector method is used for solving the governing equations and the turbulence transport equations. The stiffness arising due to source terms in the turbulence equations is handled by a semi-implicit numerical technique. Results obtained using the new model show a sharper reduction in growth rate with increasing convective Mach number. Some improvements were also noted in the prediction of the normalized streamwise stress and Reynolds shear stress. The computed results are in good agreement with the experimental data.
Effects of Sediment Patches on Sediment Transport Predictions in Steep Mountain Channels

NASA Astrophysics Data System (ADS)

Monsalve Sepulveda, A.; Yager, E.

2013-12-01

Bed surface patches occur in most gravel-bedded rivers and in steep streams can be divided between relatively immobile boulders and more mobile patches of cobbles and gravel. This spatial variability in grain size, roughness and sorting impact bed load transport by altering the relative local mobility of different grain sizes and creating complex local flow fields. Large boulders also bear a significant part of the total shear stress and we hypothesize that the remaining shear stress on a given mobile patch is a distribution of values that depend on the local topography, patch type and location relative to the large roughness elements and thalweg. Current sediment transport equations do not account for the variation in roughness, local flow and grain size distributions on and between patches and often use an area-weighted approach to obtain a representative grain size distribution and reach-averaged shear stress. Such equations also do not distinguish between active (patches where at least one grain size is in motion) and inactive patches or include the difference in mobility between patch classes as result of spatial shear stress distributions. To understand the effects of sediment patches on sediment transport in steep channels, we calculated the shear stress distributions over a range of patch classes in a 10% gradient step-pool stream. We surveyed the bed with a high density resolution (every 5 cm in horizontal and vertical directions over a 40 m long reach) using a total station and terrestrial LiDAR, mapped and classified patches by their grain size distributions, and measured water surface elevations and mean velocities for low to moderate flow events. Using these data we calibrated a quasi-three dimensional model (FaSTMECH) to obtain shear stress distributions over each patch for a range of flow discharges. We modified Parker's (1990) equations to use the calculated shear stress distribution, measured grain sizes, and a specific hiding function for each patch class, and then added the bedload fluxes for each patch to calculate the reach-averaged sediment transport rate. Sediment mobility in patches was highly dependent on the patch's class and location relative to the thalweg and large roughness elements. Compared to deterministic formulations, the use of distributions of shear stress improved predictions of bedload transport in steep mountain channels.
Three-dimensional finite element analysis of the shear bond test.

PubMed

DeHoff, P H; Anusavice, K J; Wang, Z

1995-03-01

The purpose of this study was to use finite element analyses to model the planar shear bond test and to evaluate the effects of modulus values, bonding agent thickness, and loading conditions on the stress distribution in the dentin adjacent to the bonding agent-dentin interface. All calculations were performed with the ANSYS finite element program. The planar shear bond test was modeled as a cylinder of resin-based composite bonded to a cylindrical dentin substrate. The effects of material, geometry and loading variables were determined primarily by use of a three-dimensional structural element. Several runs were also made using an axisymmetric element with harmonic loading and a plane strain element to determine whether two-dimensional analyses yield valid results. Stress calculations using three-dimensional finite element analyses confirmed the presence of large stress concentration effects for all stress components at the bonding agent-dentin interface near the application of the load. The maximum vertical shear stress generally occurs approximately 0.3 mm below the loading site and then decreases sharply in all directions. The stresses reach relatively uniform conditions within about 0.5 mm of the loading site and then increase again as the lower region of the interface is approached. Calculations using various loading conditions indicated that a wire-loop method of loading leads to smaller stress concentration effects, but a shear bond strength determined by dividing a failure load by the cross-sectional area grossly underestimates the true interfacial bond strength. Most dental researchers are using tensile and shear bond tests to predict the effects of process and material variables on the clinical performance of bonding systems but no evidence has yet shown that bond strength is relevant to clinical performance. A critical factor in assessing the usefulness of bond tests is a thorough understanding of the stress states that cause failure in the bond test and then to assess whether these stress states also exist in the clinical situation. Finite element analyses can help to answer this question but much additional work is needed to identify the failure modes in service and to relate these failures to particular loading conditions. The present study represents only a first step in understanding the stress states in the planar shear bond test.

Interaction between a normal shock wave and a turbulent boundary layer at high transonic speeds. Part 2: Wall shear stress

NASA Technical Reports Server (NTRS)

Liou, M. S.; Adamson, T. C., Jr.

1979-01-01

An analysis is presented of the flow in the two inner layers, the Reynolds stress sublayer and the wall layer. Included is the calculation of the shear stress at the wall in the interaction region. The limit processes considered are those used for an inviscid flow.
Loading direction-dependent shear behavior at different temperatures of single-layer chiral graphene sheets

NASA Astrophysics Data System (ADS)

Zhao, Yang; Dong, Shuhong; Yu, Peishi; Zhao, Junhua

2018-06-01

The loading direction-dependent shear behavior of single-layer chiral graphene sheets at different temperatures is studied by molecular dynamics (MD) simulations. Our results show that the shear properties (such as shear stress-strain curves, buckling strains, and failure strains) of chiral graphene sheets strongly depend on the loading direction due to the structural asymmetry. The maximum values of both the critical buckling shear strain and the failure strain under positive shear deformation can be around 1.4 times higher than those under negative shear deformation. For a given chiral graphene sheet, both its failure strain and failure stress decrease with increasing temperature. In particular, the amplitude to wavelength ratio of wrinkles for different chiral graphene sheets under shear deformation using present MD simulations agrees well with that from the existing theory. These findings provide physical insights into the origins of the loading direction-dependent shear behavior of chiral graphene sheets and their potential applications in nanodevices.
Analysis of flow disturbance in a stenosed carotid artery bifurcation using two-equation transitional and turbulence models.

PubMed

Tan, F P P; Soloperto, G; Bashford, S; Wood, N B; Thom, S; Hughes, A; Xu, X Y

2008-12-01

In this study, newly developed two-equation turbulence models and transitional variants are employed for the prediction of blood flow patterns in a diseased carotid artery where the growth, progression, and structure of the plaque at rupture are closely linked to low and oscillating wall shear stresses. Moreover, the laminar-turbulent transition in the poststenotic zone can alter the separation zone length, wall shear stress, and pressure distribution over the plaque, with potential implications for stresses within the plaque. Following the validation with well established experimental measurements and numerical studies, a magnetic-resonance (MR) image-based model of the carotid bifurcation with 70% stenosis was reconstructed and simulated using realistic patient-specific conditions. Laminar flow, a correlation-based transitional version of Menter's hybrid k-epsilon/k-omega shear stress transport (SST) model and its "scale adaptive simulation" (SAS) variant were implemented in pulsatile simulations from which analyses of velocity profiles, wall shear stress, and turbulence intensity were conducted. In general, the transitional version of SST and its SAS variant are shown to give a better overall agreement than their standard counterparts with experimental data for pulsatile flow in an axisymmetric stenosed tube. For the patient-specific case reported, the wall shear stress analysis showed discernable differences between the laminar flow and SST transitional models but virtually no difference between the SST transitional model and its SAS variant.
A potential model for drug screening by simulating the effect of shear stress in vivo on endothelium.

PubMed

Xu, Yingqian; Wang, Bochu; Deng, Jia; Liu, Zerong; Zhu, Liancai

2013-01-01

The purpose of this paper was to research the potential of a dynamic cell model in drug screening by studying the influence of microvascular wall shear stress on the drug absorption of endothelial cells compared to that in the static state. The cells were grown and seeded on gelatin-coated glass slides and were pretreated with extracts of Salviae miltiorrhizae (200 μg/ml) for 1 h. Then oxidative stress damage was produced by H2O2 (300 μmol/l) for 0.5 h under the 1.5 dyn/cm2 shear stress incorporated in a parallel plate flow chamber. Morphological analysis was conducted with an inverted microscope and image analysis software, and high performance liquid chromatography-mass spectrometry was used for the detection of active compounds. We compared the drug absorption in the dynamic group with that in the static group. In the dynamic model, five compounds and two new metabolite peaks were detected. However, in the static model, four compounds were absorbed by cells, and one metabolite peak was found. This study indicated that there were some effects on the absorption and metabolism of drugs under the microvascular shear stress compared to that under stasis. We infer that shear stress in the microcirculation situation in vivo played a role in causing the differences between drug screening in vitro and in vivo.
Flexible Micropost Arrays for Shear Stress Measurement

NASA Technical Reports Server (NTRS)

Wohl, Christopher J.; Palmieri, Frank L.; Hopkins, John W.; Jackson, Allen M.; Connell, John W.; Lin, Yi; Cisotto, Alexxandra A.

2015-01-01

Increased fuel costs, heightened environmental protection requirements, and noise abatement continue to place drag reduction at the forefront of aerospace research priorities. Unfortunately, shortfalls still exist in the fundamental understanding of boundary-layer airflow over aerodynamic surfaces, especially regarding drag arising from skin friction. For example, there is insufficient availability of instrumentation to adequately characterize complex flows with strong pressure gradients, heat transfer, wall mass flux, three-dimensionality, separation, shock waves, and transient phenomena. One example is the acoustic liner efficacy on aircraft engine nacelle walls. Active measurement of shear stress in boundary layer airflow would enable a better understanding of how aircraft structure and flight dynamics affect skin friction. Current shear stress measurement techniques suffer from reliability, complexity, and airflow disruption, thereby compromising resultant shear stress data. The state-of-the-art for shear stress sensing uses indirect or direct measurement techniques. Indirect measurements (e.g., hot-wire, heat flux gages, oil interferometry, laser Doppler anemometry, small scale pressure drag surfaces, i.e., fences) require intricate knowledge of the studied flow, restrictive instrument arrangements, large surface areas, flow disruption, or seeding material; with smaller, higher bandwidth probes under development. Direct measurements involve strain displacement of a sensor element and require no prior knowledge of the flow. Unfortunately, conventional "floating" recessed components for direct measurements are mm to cm in size. Whispering gallery mode devices and Fiber Bragg Gratings are examples of recent additions to this type of sensor with much smaller (?m) sensor components. Direct detection techniques are often single point measurements and difficult to calibrate and implement in wind tunnel experiments. In addition, the wiring, packaging, and installation of delicate micro-electromechanical devices impede the use of most direct shear sensors. Similarly, the cavity required for sensing element displacement is sensitive to particulate obstruction. This work was focused on developing a shear stress sensor for use in subsonic wind tunnel test facilities applicable to an array of test configurations. The non-displacement shear sensors described here have minimal packaging requirements resulting in minimal or no disturbance of boundary layer flow. Compared to previous concepts, device installation could be simple with reduced cost and down-time. The novelty lies in the creation of low profile (nanoscale to 100 µm) micropost arrays that stay within the viscous sub-layer of the airflow. Aerodynamic forces, which are related to the surface shear stress, cause post deflection and optical property changes. Ultimately, a reliable, accurate shear stress sensor that does not disrupt the airflow has the potential to provide high value data for flow physics researchers, aerodynamicists, and aircraft manufacturers leading to greater flight efficiency arising from more in-depth knowledge on how aircraft design impacts near surface properties.
Computational fluid dynamics simulation of transcatheter aortic valve degeneration.

PubMed

Dwyer, Harry A; Matthews, Peter B; Azadani, Ali; Jaussaud, Nicolas; Ge, Liang; Guy, T Sloane; Tseng, Elaine E

2009-08-01

Studied under clinical trials, transcatheter aortic valves (TAV) have demonstrated good short-term feasibility and results in high-risk surgical patients with severe aortic stenosis. However, their long-term safety and durability are unknown. The objective of this study is to evaluate hemodynamic changes within TAV created by bioprosthetic leaflet degeneration. Computational fluid dynamics (CFD) simulations were performed to evaluate the hemodynamics through TAV sclerosis (35% orifice reduction) and stenosis (78% orifice reduction). A three-dimensional surface mesh of the TAV within the aortic root was generated for each simulation. Leaflets were contained within an open, cylindrical body without attachment to the sinus commissures representing the stent. A continuous surface between the annulus and TAV excluded the geometry of the native calcified leaflets and prevented paravalvular leak. Unsteady control volume analysis throughout systole was used to calculate leaflet shear stress and total force on the TAV. Sclerosis increased total force on the TAV by 63% (0.602-0.98 N). Advancement of degeneration from sclerosis to stenosis was accompanied by an 86% increase in total force (1.82 N) but only a 32% increase in peak wall shear stress on the leaflets. Of the total force exerted on the TAV, 99% was in the direction of axial flow. Shear stresses on the TAV were greatest during peak systolic flow with stress concentrations on the tips of the leaflets. In the normal TAV, the aortic root geometry and physiologic flow dominate location and magnitude of shear stress. Following leaflet degeneration, the specific geometry of the stenosis dictates the profile of axial velocity leaving the TAV and shear stress on the leaflets. A dramatic increase in peak leaflet shear stress was observed (115 Pa stenosis vs. 87 Pa sclerosis and 29 Pa normal). CFD simulations in this study provide the first of its kind data quantifying hemodynamics within stenosed TAV. Stenosis leads to significant forces of TAV during systole; however, diastolic forces predominate even with significant stenosis. Substantial changes in peak shear stress occur with TAV degeneration. As the first implanted TAV begin to stenose, the authors recommend watchful examination for device failure.
A novel method for calculating the energy barriers for carbon diffusion in ferrite under heterogeneous stress

NASA Astrophysics Data System (ADS)

Tchitchekova, Deyana S.; Morthomas, Julien; Ribeiro, Fabienne; Ducher, Roland; Perez, Michel

2014-07-01

A novel method for accurate and efficient evaluation of the change in energy barriers for carbon diffusion in ferrite under heterogeneous stress is introduced. This method, called Linear Combination of Stress States, is based on the knowledge of the effects of simple stresses (uniaxial or shear) on these diffusion barriers. Then, it is assumed that the change in energy barriers under a complex stress can be expressed as a linear combination of these already known simple stress effects. The modifications of energy barriers by either uniaxial traction/compression and shear stress are determined by means of atomistic simulations with the Climbing Image-Nudge Elastic Band method and are stored as a set of functions. The results of this method are compared to the predictions of anisotropic elasticity theory. It is shown that, linear anisotropic elasticity fails to predict the correct energy barrier variation with stress (especially with shear stress) whereas the proposed method provides correct energy barrier variation for stresses up to ˜3 GPa. This study provides a basis for the development of multiscale models of diffusion under non-uniform stress.
A novel method for calculating the energy barriers for carbon diffusion in ferrite under heterogeneous stress.

PubMed

Tchitchekova, Deyana S; Morthomas, Julien; Ribeiro, Fabienne; Ducher, Roland; Perez, Michel

2014-07-21

A novel method for accurate and efficient evaluation of the change in energy barriers for carbon diffusion in ferrite under heterogeneous stress is introduced. This method, called Linear Combination of Stress States, is based on the knowledge of the effects of simple stresses (uniaxial or shear) on these diffusion barriers. Then, it is assumed that the change in energy barriers under a complex stress can be expressed as a linear combination of these already known simple stress effects. The modifications of energy barriers by either uniaxial traction/compression and shear stress are determined by means of atomistic simulations with the Climbing Image-Nudge Elastic Band method and are stored as a set of functions. The results of this method are compared to the predictions of anisotropic elasticity theory. It is shown that, linear anisotropic elasticity fails to predict the correct energy barrier variation with stress (especially with shear stress) whereas the proposed method provides correct energy barrier variation for stresses up to ∼3 GPa. This study provides a basis for the development of multiscale models of diffusion under non-uniform stress.
Foam rheology at large deformation

NASA Astrophysics Data System (ADS)

Géminard, J.-C.; Pastenes, J. C.; Melo, F.

2018-04-01

Large deformations are prone to cause irreversible changes in materials structure, generally leading to either material hardening or softening. Aqueous foam is a metastable disordered structure of densely packed gas bubbles. We report on the mechanical response of a foam layer subjected to quasistatic periodic shear at large amplitude. We observe that, upon increasing shear, the shear stress follows a universal curve that is nearly exponential and tends to an asymptotic stress value interpreted as the critical yield stress at which the foam structure is completely remodeled. Relevant trends of the foam mechanical response to cycling are mathematically reproduced through a simple law accounting for the amount of plastic deformation upon increasing stress. This view provides a natural interpretation to stress hardening in foams, demonstrating that plastic effects are present in this material even for minute deformation.
Effect of Boundary Condition on the Shear Behaviour of Rock Joints in the Direct Shear Test

NASA Astrophysics Data System (ADS)

Bahaaddini, M.

2017-05-01

The common method for determination of the mechanical properties of the rock joints is the direct shear test. This paper aims to study the effect of boundary condition on the results of direct shear tests. Experimental studies undertaken in this research showed that the peak shear strength is mostly overestimated. This problem is more pronounced for steep asperities and under high normal stresses. Investigation of the failure mode of these samples showed that tensile cracks are generated at the boundary of sample close to the specimen holders and propagated inside the intact materials. In order to discover the reason of observed failure mechanism in experiments, the direct shear test was simulated using PFC2D. Results of numerical models showed that the gap zone size between the upper and lower specimen holders has a significant effect on the shear mechanism. For the high gap size, stresses concentrate at the vicinity of the tips of specimen holders and result in generation and propagation of tensile cracks inside the intact material. However, by reducing the gap size, stresses are concentrated on asperities, and damage of specimen at its boundary is not observed. Results of this paper show that understanding the shear mechanism of rock joints is an essential step prior to interpreting the results of direct shear tests.
Modeling cell-substrate de-adhesion dynamics under fluid shear

NASA Astrophysics Data System (ADS)

Maan, Renu; Rani, Garima; Menon, Gautam I.; Pullarkat, Pramod A.

2018-07-01

Changes in cell-substrate adhesion are believed to signal the onset of cancer metastasis, but such changes must be quantified against background levels of intrinsic heterogeneity between cells. Variations in cell-substrate adhesion strengths can be probed through biophysical measurements of cell detachment from substrates upon the application of an external force. Here, we investigate, theoretically and experimentally, the detachment of cells adhered to substrates when these cells are subjected to fluid shear. We present a theoretical framework within which we calculate the fraction of detached cells as a function of shear stress for fast ramps as well as the decay in this fraction at fixed shear stress as a function of time. Using HEK and 3T3 fibroblast cells as experimental model systems, we extract characteristic force scales for cell adhesion as well as characteristic detachment times. We estimate force-scales of ∼500 pN associated to a single focal contact, and characteristic time-scales of s representing cell-spread-area dependent mean first passage times to the detached state at intermediate values of the shear stress. Variations in adhesion across cell types are especially prominent when cell detachment is probed by applying a time-varying shear stress. These methods can be applied to characterizing changes in cell adhesion in a variety of contexts, including metastasis.
DEM study of fabric features governing undrained post-liquefaction shear deformation of sand

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Rui; Fu, Pengcheng; Zhang, Jian-Min

In an effort to study undrained post-liquefaction shear deformation of sand, the discrete element method (DEM) is adopted to conduct undrained cyclic biaxial compression simulations on granular assemblies consisting of 2D circular particles. The simulations are able to successfully reproduce the generation and eventual saturation of shear strain through the series of liquefaction states that the material experiences during cyclic loading after the initial liquefaction. Also, DEM simulations with different deviatoric stress amplitudes and initial mean effective stresses on samples with different void ratios and loading histories are carried out to investigate the relationship between various mechanics- or fabric-related variablesmore » and post-liquefaction shear strain development. It is found that well-known metrics such as deviatoric stress amplitude, initial mean effective stress, void ratio, contact normal fabric anisotropy intensity, and coordination number, are not adequately correlated to the observed shear strain development and, therefore, could not possibly be used for its prediction. A new fabric entity, namely the Mean Neighboring Particle Distance (MNPD), is introduced to reflect the space arrangement of particles. It is found that the MNPD has an extremely strong and definitive relationship with the post-liquefaction shear strain development, showing MNPD’s potential role as a parameter governing post-liquefaction behavior of sand.« less
DEM study of fabric features governing undrained post-liquefaction shear deformation of sand

DOE PAGES

Wang, Rui; Fu, Pengcheng; Zhang, Jian-Min; ...

2016-10-05

In an effort to study undrained post-liquefaction shear deformation of sand, the discrete element method (DEM) is adopted to conduct undrained cyclic biaxial compression simulations on granular assemblies consisting of 2D circular particles. The simulations are able to successfully reproduce the generation and eventual saturation of shear strain through the series of liquefaction states that the material experiences during cyclic loading after the initial liquefaction. Also, DEM simulations with different deviatoric stress amplitudes and initial mean effective stresses on samples with different void ratios and loading histories are carried out to investigate the relationship between various mechanics- or fabric-related variablesmore » and post-liquefaction shear strain development. It is found that well-known metrics such as deviatoric stress amplitude, initial mean effective stress, void ratio, contact normal fabric anisotropy intensity, and coordination number, are not adequately correlated to the observed shear strain development and, therefore, could not possibly be used for its prediction. A new fabric entity, namely the Mean Neighboring Particle Distance (MNPD), is introduced to reflect the space arrangement of particles. It is found that the MNPD has an extremely strong and definitive relationship with the post-liquefaction shear strain development, showing MNPD’s potential role as a parameter governing post-liquefaction behavior of sand.« less
The significance of relative density for particle damage in loaded and sheared gravels

NASA Astrophysics Data System (ADS)

Fityus, Stephen; Imre, Emőke

2017-06-01

For granular assemblages of strong particles, an increase in the relative density usually leads to a significant increase in shear strength, which is evident as a peak strength, accompanied by significant dilation as the peak strength is attained. This paper describes an experimental study of shearing in assemblages of weak particles, where particle breakage offsets dilation for all but the lowest of confining stresses. In such materials, prone to particle breakage, the shear strengths of loose and dense assemblages rapidly converge to similar values as confining stress increases, and any benefit of greater relative density is lost. This is attributed to the densification effect associated with the loading under a high stress prior to shearing, which is characterised by widespread particle breakage and the formation of smaller particles to occupy space between coarser ones. Interestingly, under both low and high stresses, there was a tendency for greater particle breakage in the loose samples, as a result of both shearing and compression. This result suggests that, despite the denser assemblage having its particles more rigidly constrained and less able to rearrange to avoid direct loading, the influence of greater load-spreading capacity afforded by an increased number of particle contacts in a denser sample, is more dominant in controlling breakage.
The role of shear and tensile failure in dynamically triggered landslides

USGS Publications Warehouse

Gipprich, T.L.; Snieder, R.K.; Jibson, R.W.; Kimman, W.

2008-01-01

Dynamic stresses generated by earthquakes can trigger landslides. Current methods of landslide analysis such as pseudo-static analysis and Newmark's method focus on the effects of earthquake accelerations on the landslide mass to characterize dynamic landslide behaviour. One limitation of these methods is their use Mohr-Coulomb failure criteria, which only accounts for shear failure, but the role of tensile failure is not accounted for. We develop a limit-equilibrium model to investigate the dynamic stresses generated by a given ground motion due to a plane wave and use this model to assess the role of shear and tensile failure in the initiation of slope instability. We do so by incorporating a modified Griffith failure envelope, which combines shear and tensile failure into a single criterion. Tests of dynamic stresses in both homogeneous and layered slopes demonstrate that two modes of failure exist, tensile failure in the uppermost meters of a slope and shear failure at greater depth. Further, we derive equations that express the dynamic stress in the near-surface in the acceleration measured at the surface. These equations are used to approximately define the depth range for each mechanism of failure. The depths at which these failure mechanisms occur suggest that shear and tensile failure might collaborate in generating slope failure. ?? 2007 The Authors Journal compilation ?? 2007 RAS.
Nonlinear viscoelastic characterization of human vocal fold tissues under large-amplitude oscillatory shear (LAOS)

PubMed Central

Chan, Roger W.

2018-01-01

Viscoelastic shear properties of human vocal fold tissues were previously quantified by the shear moduli (G′ and G″). Yet these small-strain linear measures were unable to describe any nonlinear tissue behavior. This study attempted to characterize the nonlinear viscoelastic response of the vocal fold lamina propria under large-amplitude oscillatory shear (LAOS) with a stress decomposition approach. Human vocal fold cover and vocal ligament specimens from eight subjects were subjected to LAOS rheometric testing with a simple-shear rheometer. The empirical total stress response was decomposed into elastic and viscous stress components, based on odd-integer harmonic decomposition approach with Fourier transform. Nonlinear viscoelastic measures derived from the decomposition were plotted in Pipkin space and as rheological fingerprints to observe the onset of nonlinearity and the type of nonlinear behavior. Results showed that both the vocal fold cover and the vocal ligament experienced intercycle strain softening, intracycle strain stiffening, as well as shear thinning both intercycle and intracycle. The vocal ligament appeared to demonstrate an earlier onset of nonlinearity at phonatory frequencies, and higher sensitivity to changes in frequency and strain. In summary, the stress decomposition approach provided much better insights into the nonlinear viscoelastic behavior of the vocal fold lamina propria than the traditional linear measures. PMID:29780189
Nonlinear viscoelastic characterization of human vocal fold tissues under large-amplitude oscillatory shear (LAOS).

PubMed

Chan, Roger W

2018-05-01

Viscoelastic shear properties of human vocal fold tissues were previously quantified by the shear moduli ( G' and G″ ). Yet these small-strain linear measures were unable to describe any nonlinear tissue behavior. This study attempted to characterize the nonlinear viscoelastic response of the vocal fold lamina propria under large-amplitude oscillatory shear (LAOS) with a stress decomposition approach. Human vocal fold cover and vocal ligament specimens from eight subjects were subjected to LAOS rheometric testing with a simple-shear rheometer. The empirical total stress response was decomposed into elastic and viscous stress components, based on odd-integer harmonic decomposition approach with Fourier transform. Nonlinear viscoelastic measures derived from the decomposition were plotted in Pipkin space and as rheological fingerprints to observe the onset of nonlinearity and the type of nonlinear behavior. Results showed that both the vocal fold cover and the vocal ligament experienced intercycle strain softening, intracycle strain stiffening, as well as shear thinning both intercycle and intracycle. The vocal ligament appeared to demonstrate an earlier onset of nonlinearity at phonatory frequencies, and higher sensitivity to changes in frequency and strain. In summary, the stress decomposition approach provided much better insights into the nonlinear viscoelastic behavior of the vocal fold lamina propria than the traditional linear measures.
Dynamic shear-stress-enhanced rates of nutrient consumption in gas-liquid semi-continuous-flow suspensions

NASA Astrophysics Data System (ADS)

Belfiore, Laurence A.; Volpato, Fabio Z.; Paulino, Alexandre T.; Belfiore, Carol J.

2011-12-01

The primary objective of this investigation is to establish guidelines for generating significant mammalian cell density in suspension bioreactors when stress-sensitive kinetics enhance the rate of nutrient consumption. Ultra-low-frequency dynamic modulations of the impeller (i.e., 35104 Hz) introduce time-dependent oscillatory shear into this transient analysis of cell proliferation under semi-continuous creeping flow conditions. Greater nutrient consumption is predicted when the amplitude A of modulated impeller rotation increases, and stress-kinetic contributions to nutrient consumption rates increase linearly at higher modulation frequency via an application of fluctuation-dissipation response. Interphase mass transfer is required to replace dissolved oxygen as it is consumed by aerobic nutrient consumption in the liquid phase. The theory and predictions described herein could be important at small length scales in the creeping flow regime where viscous shear is significant at the interface between the nutrient medium and isolated cells in suspension. Two-dimensional flow around spherically shaped mammalian cells, suspended in a Newtonian culture medium, is analyzed to calculate the surface-averaged magnitude of the velocity gradient tensor and modify homogeneous rates of nutrient consumption that are stimulated by viscous shear, via the formalism of stress-kinetic reciprocal relations that obey Curie's theorem in non-equilibrium thermodynamics. Time constants for stress-free free and stress-sensitive stress nutrient consumption are defined and quantified to identify the threshold (i.e., stress,threshold) below which the effect of stress cannot be neglected in accurate predictions of bioreactor performance. Parametric studies reveal that the threshold time constant for stress-sensitive nutrient consumption stress,threshold decreases when the time constant for stress-free nutrient consumption free is shorter. Hence, stress,threshold depends directly on free. In other words, the threshold rate of stress-sensitive nutrient consumption is higher when the stress-free rate of nutrient consumption increases. Modulated rotation of the impeller, superimposed on steady shear, increases stress,threshold when free is constant, and stress,threshold depends directly on the amplitude A of these angular velocity modulations.
Enhanced torsional actuation and stress coupling in Mn-modified 0.93(Na 0.5Bi 0.5TiO 3)-0.07BaTiO 3 lead-free piezoceramic system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Berik, Pelin; Maurya, Deepam; Kumar, Prashant

This paper is concerned with the development of a piezoelectric d 15 shear-induced torsion actuator made of a lead-free piezoceramic material exhibiting giant piezoelectric shear stress coefficient (e 15) and piezoelectric transverse shear actuation force comparable to that of leadbased shear-mode piezoceramics. The Mn-modified 0.93(Na 0.5Bi 0.5TiO 3)-0.07BaTiO 3 (NBT-BTMn) composition exhibited excellent properties as a torsional transducer with piezoelectric shear stress coefficient on the order of 11.6 C m –2. The torsional transducer, consisting of two oppositely polarized NBT-BT-Mn d 15 mode piezoceramic shear patches, provided a rate of twist of 0.08 mm m –1 V –1 under quasi-staticmore » 150 V drive. The high value of piezoelectric shear d 15 coefficient in NBT-BT-Mn sample further demonstrated its potential in practical applications. Lastly, these results confirm that the lead-free piezoceramics can be as effective as their lead-based counterparts.« less
Enhanced torsional actuation and stress coupling in Mn-modified 0.93(Na0.5Bi0.5TiO3)-0.07BaTiO3 lead-free piezoceramic system

PubMed Central

Berik, Pelin; Maurya, Deepam; Kumar, Prashant; Kang, Min Gyu; Priya, Shashank

2017-01-01

Abstract This paper is concerned with the development of a piezoelectric d 15 shear-induced torsion actuator made of a lead-free piezoceramic material exhibiting giant piezoelectric shear stress coefficient (e 15) and piezoelectric transverse shear actuation force comparable to that of lead-based shear-mode piezoceramics. The Mn-modified 0.93(Na0.5Bi0.5TiO3)-0.07BaTiO3 (NBT-BT-Mn) composition exhibited excellent properties as a torsional transducer with piezoelectric shear stress coefficient on the order of 11.6 C m–2. The torsional transducer, consisting of two oppositely polarized NBT-BT-Mn d 15 mode piezoceramic shear patches, provided a rate of twist of 0.08 mm m–1 V–1 under quasi-static 150 V drive. The high value of piezoelectric shear d 15 coefficient in NBT-BT-Mn sample further demonstrated its potential in practical applications. These results confirm that the lead-free piezoceramics can be as effective as their lead-based counterparts. PMID:28179958

A Bayesian approach to modelling the impact of hydrodynamic shear stress on biofilm deformation

PubMed Central

Wilkinson, Darren J.; Jayathilake, Pahala Gedara; Rushton, Steve P.; Bridgens, Ben; Li, Bowen; Zuliani, Paolo

2018-01-01

We investigate the feasibility of using a surrogate-based method to emulate the deformation and detachment behaviour of a biofilm in response to hydrodynamic shear stress. The influence of shear force, growth rate and viscoelastic parameters on the patterns of growth, structure and resulting shape of microbial biofilms was examined. We develop a statistical modelling approach to this problem, using combination of Bayesian Poisson regression and dynamic linear models for the emulation. We observe that the hydrodynamic shear force affects biofilm deformation in line with some literature. Sensitivity results also showed that the expected number of shear events, shear flow, yield coefficient for heterotrophic bacteria and extracellular polymeric substance (EPS) stiffness per unit EPS mass are the four principal mechanisms governing the bacteria detachment in this study. The sensitivity of the model parameters is temporally dynamic, emphasising the significance of conducting the sensitivity analysis across multiple time points. The surrogate models are shown to perform well, and produced ≈ 480 fold increase in computational efficiency. We conclude that a surrogate-based approach is effective, and resulting biofilm structure is determined primarily by a balance between bacteria growth, viscoelastic parameters and applied shear stress. PMID:29649240
Enhanced torsional actuation and stress coupling in Mn-modified 0.93(Na 0.5Bi 0.5TiO 3)-0.07BaTiO 3 lead-free piezoceramic system

DOE PAGES

Berik, Pelin; Maurya, Deepam; Kumar, Prashant; ...

2017-01-09

This paper is concerned with the development of a piezoelectric d 15 shear-induced torsion actuator made of a lead-free piezoceramic material exhibiting giant piezoelectric shear stress coefficient (e 15) and piezoelectric transverse shear actuation force comparable to that of leadbased shear-mode piezoceramics. The Mn-modified 0.93(Na 0.5Bi 0.5TiO 3)-0.07BaTiO 3 (NBT-BTMn) composition exhibited excellent properties as a torsional transducer with piezoelectric shear stress coefficient on the order of 11.6 C m –2. The torsional transducer, consisting of two oppositely polarized NBT-BT-Mn d 15 mode piezoceramic shear patches, provided a rate of twist of 0.08 mm m –1 V –1 under quasi-staticmore » 150 V drive. The high value of piezoelectric shear d 15 coefficient in NBT-BT-Mn sample further demonstrated its potential in practical applications. Lastly, these results confirm that the lead-free piezoceramics can be as effective as their lead-based counterparts.« less
Global method for measuring stress in polymer fibers at elevated temperatures

NASA Astrophysics Data System (ADS)

Anagnostopoulos, G.; Andreopoulos, A. G.; Parthenios, J.; Galiotis, C.

2005-09-01

In this work, a methodology is presented for evaluating the interfacial shear stress as well as the corresponding axial stress in full polymer fiber reinforced materials under elevated temperatures. Its validity was confirmed by deriving interfacial shear and axial stress expressions for embedded Kevlar® 29 fibers within an epoxy matrix by means of Raman microscopy. This approach can be established to other systems such as carbon or polyethylene fiber composites, for which the observed Raman bands are both stress and temperature sensitive.
Frequency and Wavevector Dependence of the Atomic Level Stress-Stress Correlation Function in a Model Supercooled Liquid

NASA Astrophysics Data System (ADS)

Levashov, Valentin A.; Morris, James R.; Egami, Takeshi

2012-02-01

Temporal and spatial correlations among the local atomic level shear stresses were studied for a model liquid iron by molecular dynamics simulation [PRL 106,115703]. Integration over time and space of the shear stress correlation function F(r,t) yields viscosity via Green-Kubo relation. The stress correlation function in time and space F(r,t) was Fourier transformed to study the dependence on frequency, E, and wave vector, Q. The results, F(Q,E), showed damped shear stress waves propagating in the liquid for small Q at high and low temperatures. We also observed additional diffuse feature that appears as temperature is reduced below crossover temperature of potential energy landscape at relatively low frequencies at small Q. We suggest that this additional feature might be related to dynamic heterogeneity and boson peaks. We also discuss a relation between the time-scale of the stress-stress correlation function and the alpha-relaxation time of the intermediate self-scattering function S(Q,E).
Mechanical Evolution and Dynamics of Decollement Slip in Contractional Systems: Correlating Macro- and Micro-Scale Processes in Particle Dynamics Simulation

NASA Astrophysics Data System (ADS)

Morgan, J. K.

2014-12-01

Particle-based numerical simulations allow detailed investigations of small-scale processes and mechanisms associated with fault initiation and slip, which emerge naturally in such models. This study investigates the evolving mechanical conditions and associated micro-mechanisms during transient slip on a weak decollement propagating beneath a growing contractional wedge (e.g., accretionary prism, fold and thrust belt). The models serve as analogs of the seismic cycle, although lacking full earthquake dynamics. Nonetheless, the mechanical evolution of both decollement and upper plate can be monitored, and correlated with the particle-scale physical and contact properties, providing insights into changes that accompany such stick-slip behavior. In this study, particle assemblages consolidated under gravity and bonded to impart cohesion, are pushed at a constant velocity above a weak, unbonded decollement surface. Forward propagation of decollement slip occurs in discrete pulses, modulated by heterogeneous stress conditions (e.g., roughness, contact bridging) along the fault. Passage of decollement slip resets the stress along this horizon, producing distinct patterns: shear stress is enhanced in front of the slipped decollement due to local contact bridging and fault locking; shear stress minima occur immediately above the tip, denoting local stress release and contact reorganization following slip; more mature portions of the fault exhibit intermediate shear stress, reflecting more stable contact force distributions and magnitudes. This pattern of shear stress pre-conditions the decollement for future slip events, which must overcome the high stresses at the fault tip. Long-term slip along the basal decollement induces upper plate contraction. When upper plate stresses reach critical strength conditions, new thrust faults break through the upper plate, relieving stresses and accommodating horizontal shortening. Decollement activity retreats back to the newly formed thrust fault. The cessation of upper plate fault slip causes gradual increases in upper plate stresses, rebuilding shear stresses along the decollement and enabling renewed pulses of decollement slip. Thus, upper plate deformation occurs out of phase with decollement propagation.
BOUNDARY SHEAR STRESS ALONG VEGETATED STREAMBANKS

EPA Science Inventory

This research is intended to improve our understanding of the role of riparian vegetation in stream morphology by evaluating the effects of vegetation on boundary shear stress, providing insight to the type and density of vegetation required for streambank stability. The resu...
Representation of turbulent shear stress by a product of mean velocity differences

NASA Technical Reports Server (NTRS)

Braun, W. H.

1977-01-01

A quadratic form in the mean velocity for the turbulent shear stress is presented. It is expressed as the product of two velocity differences whose roots are the maximum velocity in the flow and a cutoff velocity below which the turbulent shear stress vanishes. Application to pipe and channel flows yields the centerline velocity as a function of pressure gradient, as well as the velocity profile. The flat plate, boundary-layer problem is solved by a system of integral equations to obtain friction coefficient, displacement thickness, and momentum-loss thickness. Comparisons are made with experiment.
DOE Office of Scientific and Technical Information (OSTI.GOV)

Pashkin, E. Y.; Pankov, A. M.; Kulnitskiy, B. A.

The behavior of multiwall carbon nanotubes under a high pressure (up to 55 GPa) combined with shear deformation was studied by experimental and theoretical methods. The unexpectedly high stability of the nanotubes' structure under high stresses was observed. After the pressure was released, we observed that the nanotubes had restored their shapes. Atomistic simulations show that the hydrostatic and shear stresses affect the nanotubes' structure in a different way. It was found that the shear stress load in the multiwall nanotubes' outer walls can induce their connection and formation of an amorphized sp{sup 3}-hybridized region but internal core keeps the tubularmore » structure.« less
Preliminary Study for Measurement of Shear Stress and Hemocompatibility Using Commercialized Lab on a Chip.

PubMed

Lee, Joshua; Kim, In Gi; Oh, Young Min; Park, Chan-Hee; Kim, Cheol Sang

2018-02-01

We have investigated the effect of flow rate on shear stress and in turn thrombus formation on a lab-on-a-chip with a microchannel that is suitable for cell culture and growth. Using a combination of Arduino UNO, Arduino Motor Shield, and a SERVO stepper motor, we created a pump system that closely mimics the in vivo conditions of the human body. With this system, we achieved continuous flow of blood and observed attached platelets at the bottom of the collagen coated microslide, confirming that with shear stress, thrombus formation increases.
Laminar shear stress modulates endothelial luminal surface stiffness in a tissue-specific manner.

PubMed

Merna, Nick; Wong, Andrew K; Barahona, Victor; Llanos, Pierre; Kunar, Balvir; Palikuqi, Brisa; Ginsberg, Michael; Rafii, Shahin; Rabbany, Sina Y

2018-04-17

Endothelial cells form vascular beds in all organs and are exposed to a range of mechanical forces that regulate cellular phenotype. We sought to determine the role of endothelial luminal surface stiffness in tissue-specific mechanotransduction of laminar shear stress in microvascular mouse cells and the role of arachidonic acid in mediating this response. Microvascular mouse endothelial cells were subjected to laminar shear stress at 4 dynes/cm 2 for 12 hours in parallel plate flow chambers that enabled real-time optical microscopy and atomic force microscopy measurements of cell stiffness. Lung endothelial cells aligned parallel to flow, while cardiac endothelial cells did not. This rapid alignment was accompanied by increased cell stiffness. The addition of arachidonic acid to cardiac endothelial cells increased alignment and stiffness in response to shear stress. Inhibition of arachidonic acid in lung endothelial cells and embryonic stem cell-derived endothelial cells prevented cellular alignment and decreased cell stiffness. Our findings suggest that increased endothelial luminal surface stiffness in microvascular cells may facilitate mechanotransduction and alignment in response to laminar shear stress. Furthermore, the arachidonic acid pathway may mediate this tissue-specific process. An improved understanding of this response will aid in the treatment of organ-specific vascular disease. © 2018 John Wiley & Sons Ltd.
Convection of wall shear stress events in a turbulent boundary layer

NASA Astrophysics Data System (ADS)

Pabon, Rommel; Mills, David; Ukeiley, Lawrence; Sheplak, Mark

2017-11-01

The fluctuating wall shear stress is measured in a zero pressure gradient turbulent boundary layer of Reτ 1700 simultaneously with velocity measurements using either hot-wire anemometry or particle image velocimetry. These experiments elucidate the patterns of large scale structures in a single point measurement of the wall shear stress, as well as their convection velocity at the wall. The wall shear stress sensor is a CS-A05 one-dimensional capacitice floating element from Interdisciplinary Consulting Corp. It has a nominal bandwidth from DC to 5 kHz and a floating element size of 1 mm in the principal sensing direction (streamwise) and 0.2 mm in the cross direction (spanwise), allowing the large scales to be well resolved in the current experimental conditions. In addition, a two sensor array of CS-A05 aligned in the spanwise direction with streamwise separations O (δ) is utilized to capture the convection velocity of specific scales of the shear stress through a bandpass filter and peaks in the correlation. Thus, an average wall normal position for the corresponding convecting event can be inferred at least as high as the equivalent local streamwise velocity. This material is based upon work supported by the National Science Foundation Graduate Research Fellowship under Grant No. DGE-1315138.
Diagnostics of boundary layer transition by shear stress sensitive liquid crystals

NASA Astrophysics Data System (ADS)

Shapoval, E. S.

2016-10-01

Previous research indicates that the problem of boundary layer transition visualization on metal models in wind tunnels (WT) which is a fundamental question in experimental aerodynamics is not solved yet. In TsAGI together with Khristianovich Institute of Theoretical and Applied Mechanics (ITAM) a method of shear stress sensitive liquid crystals (LC) which allows flow visualization was proposed. This method allows testing several flow conditions in one wind tunnel run and does not need covering the investigated model with any special heat-insulating coating which spoils the model geometry. This coating is easily applied on the model surface by spray or even by brush. Its' thickness is about 40 micrometers and it does not spoil the surface quality. At first the coating obtains some definite color. Under shear stress the LC coating changes color and this change is proportional to shear stress. The whole process can be visually observed and during the tests it is recorded by camera. The findings of the research showed that it is possible to visualize boundary layer transition, flow separation, shock waves and the flow image on the whole. It is possible to predict that the proposed method of shear stress sensitive liquid crystals is a promise for future research.
Dynamic Adhesion of Umbilical Cord Blood Endothelial Progenitor Cells under Laminar Shear Stress

PubMed Central

Angelos, Mathew G.; Brown, Melissa A.; Satterwhite, Lisa L.; Levering, Vrad W.; Shaked, Natan T.; Truskey, George A.

2010-01-01

Late outgrowth endothelial progenitor cells (EPCs) represent a promising cell source for rapid reendothelialization of damaged vasculature after expansion ex vivo and injection into the bloodstream. We characterized the dynamic adhesion of umbilical-cord-blood-derived EPCs (CB-EPCs) to surfaces coated with fibronectin. CB-EPC solution density affected the number of adherent cells and larger cells preferentially adhered at lower cell densities. The number of adherent cells varied with shear stress, with the maximum number of adherent cells and the shear stress at maximum adhesion depending upon fluid viscosity. CB-EPCs underwent limited rolling, transiently tethering for short distances before firm arrest. Immediately before arrest, the instantaneous velocity decreased independent of shear stress. A dimensional analysis indicated that adhesion was a function of the net force on the cells, the ratio of cell diffusion to sliding speed, and molecular diffusivity. Adhesion was not limited by the settling rate and was highly specific to α5β1 integrin. Total internal reflection fluorescence microscopy showed that CB-EPCs produced multiple contacts of α5β1 with the surface and the contact area grew during the first 20 min of attachment. These results demonstrate that CB-EPC adhesion from blood can occur under physiological levels of shear stress. PMID:21112278
Bolt axial stress measurement based on a mode-converted ultrasound method using an electromagnetic acoustic transducer.

PubMed

Ding, Xu; Wu, Xinjun; Wang, Yugang

2014-03-01

A method is proposed to measure the stress on a tightened bolt using an electromagnetic acoustic transducer (EMAT). A shear wave is generated by the EMAT, and a longitudinal wave is obtained from the reflection of the shear wave due to the mode conversion. The ray paths of the longitudinal and the shear wave are analyzed, and the relationship between the bolt axial stress and the ratio of time of flight between two mode waves is then formulated. Based on the above outcomes, an EMAT is developed to measure the bolt axial stress without loosening the bolt, which is required in the conventional EMAT test method. The experimental results from the measurement of the bolt tension show that the shear and the mode-converted longitudinal waves can be received successfully, and the ratio of the times of flight of the shear and the mode-converted longitudinal waves is linearly proportional to the bolt axial tension. The non-contact characteristic of EMAT eliminates the effect of the couplant and also makes the measurement more convenient than the measurement performed using the piezoelectric transducer. This method provides a promising way to measure the stress on tightened bolts. Copyright © 2013 Elsevier B.V. All rights reserved.
Simultaneous wall-shear-stress and wide-field PIV measurements in a turbulent boundary layer

NASA Astrophysics Data System (ADS)

Gomit, Guillaume; Fourrie, Gregoire; de Kat, Roeland; Ganapathisubramani, Bharathram

2015-11-01

Simultaneous particle image velocimetry (PIV) and hot-film shear stress sensor measurements were performed to study the large-scale structures associated with shear stress events in a flat plate turbulent boundary layer at a high Reynolds number (Reτ ~ 4000). The PIV measurement was performed in a streamwise-wall normal plane using an array of six high resolution cameras (4 ×16MP and 2 ×29MP). The resulting field of view covers 8 δ (where δ is the boundary layer thickness) in the streamwise direction and captures the entire boundary layer in the wall-normal direction. The spatial resolution of the measurement is approximately is approximately 70 wall units (1.8 mm) and sampled each 35 wall units (0.9 mm). In association with the PIV setup, a spanwise array of 10 skin-friction sensors (spanning one δ) was used to capture the footprint of the large-scale structures. This combination of measurements allowed the analysis of the three-dimensional conditional structures in the boundary layer. Particularly, from conditional averages, the 3D organisation of the wall normal and streamwise velocity components (u and v) and the Reynolds shear stress (-u'v') related to a low and high shear stress events can be extracted. European Research Council Grant No-277472-WBT.
Viscoelastic flow past mono- and bidisperse random arrays of cylinders: flow resistance, topology and normal stress distribution.

PubMed

De, S; Kuipers, J A M; Peters, E A J F; Padding, J T

2017-12-13

We investigate creeping viscoelastic fluid flow through two-dimensional porous media consisting of random arrangements of monodisperse and bidisperse cylinders, using our finite volume-immersed boundary method introduced in S. De, et al., J. Non-Newtonian Fluid Mech., 2016, 232, 67-76. The viscoelastic fluid is modeled with a FENE-P model. The simulations show an increased flow resistance with increase in flow rate, even though the bulk response of the fluid to shear flow is shear thinning. We show that if the square root of the permeability is chosen as the characteristic length scale in the determination of the dimensionless Deborah number (De), then all flow resistance curves collapse to a single master curve, irrespective of the pore geometry. Our study reveals how viscoelastic stresses and flow topologies (rotation, shear and extension) are distributed through the porous media, and how they evolve with increasing De. We correlate the local viscoelastic first normal stress differences with the local flow topology and show that the largest normal stress differences are located in shear flow dominated regions and not in extensional flow dominated regions at higher viscoelasticity. The study shows that normal stress differences in shear flow regions may play a crucial role in the increase of flow resistance for viscoelastic flow through such porous media.
Strain Rate Sensitivity of Epoxy Resin in Tensile and Shear Loading

NASA Technical Reports Server (NTRS)

Gilat, Amos; Goldberg, Robert K.; Roberts, Gary D.

2005-01-01

The mechanical response of E-862 and PR-520 resins is investigated in tensile and shear loadings. At both types of loading the resins are tested at strain rates of about 5x10(exp 5), 2, and 450 to 700 /s. In addition, dynamic shear modulus tests are carried out at various frequencies and temperatures, and tensile stress relaxation tests are conducted at room temperature. The results show that the toughened PR-520 resin can carry higher stresses than the untoughened E-862 resin. Strain rate has a significant effect on the response of both resins. In shear both resins show a ductile response with maximum stress that is increasing with strain rate. In tension a ductile response is observed at low strain rate (approx. 5x10(exp 5) /s), and brittle response is observed at the medium and high strain rates (2, and 700 /s). The hydrostatic component of the stress in the tensile tests causes premature failure in the E-862 resin. Localized deformation develops in the PR-520 resin when loaded in shear. An internal state variable constitutive model is proposed for modeling the response of the resins. The model includes a state variable that accounts for the effect of the hydrostatic component of the stress on the deformation.
Assessment of shear stress related parameters in the carotid bifurcation using mouse-specific FSI simulations.

PubMed

De Wilde, David; Trachet, Bram; Debusschere, Nic; Iannaccone, Francesco; Swillens, Abigail; Degroote, Joris; Vierendeels, Jan; De Meyer, Guido R Y; Segers, Patrick

2016-07-26

The ApoE(-)(/)(-) mouse is a common small animal model to study atherosclerosis, an inflammatory disease of the large and medium sized arteries such as the carotid artery. It is generally accepted that the wall shear stress, induced by the blood flow, plays a key role in the onset of this disease. Wall shear stress, however, is difficult to derive from direct in vivo measurements, particularly in mice. In this study, we integrated in vivo imaging (micro-Computed Tomography-µCT and ultrasound) and fluid-structure interaction (FSI) modeling for the mouse-specific assessment of carotid hemodynamics and wall shear stress. Results were provided for 8 carotid bifurcations of 4 ApoE(-)(/)(-) mice. We demonstrated that accounting for the carotid elasticity leads to more realistic flow waveforms over the complete domain of the model due to volume buffering capacity in systole. The 8 simulated cases showed fairly consistent spatial distribution maps of time-averaged wall shear stress (TAWSS) and relative residence time (RRT). Zones with reduced TAWSS and elevated RRT, potential indicators of atherosclerosis-prone regions, were located mainly at the outer sinus of the external carotid artery. In contrast to human carotid hemodynamics, no flow recirculation could be observed in the carotid bifurcation region. Copyright © 2015 Elsevier Ltd. All rights reserved.
Hydrostatic pressure and shear stress affect endothelin-1 and nitric oxide release by endothelial cells in bioreactors.

PubMed

Vozzi, Federico; Bianchi, Francesca; Ahluwalia, Arti; Domenici, Claudio

2014-01-01

Abundant experimental evidence demonstrates that endothelial cells are sensitive to flow; however, the effect of fluid pressure or pressure gradients that are used to drive viscous flow is not well understood. There are two principal physical forces exerted on the blood vessel wall by the passage of intra-luminal blood: pressure and shear. To analyze the effects of pressure and shear independently, these two stresses were applied to cultured cells in two different types of bioreactors: a pressure-controlled bioreactor and a laminar flow bioreactor, in which controlled levels of pressure or shear stress, respectively, can be generated. Using these bioreactor systems, endothelin-1 (ET-1) and nitric oxide (NO) release from human umbilical vein endothelial cells were measured under various shear stress and pressure conditions. Compared to the controls, a decrease of ET-1 production by the cells cultured in both bioreactors was observed, whereas NO synthesis was up-regulated in cells under shear stress, but was not modulated by hydrostatic pressure. These results show that the two hemodynamic forces acting on blood vessels affect endothelial cell function in different ways, and that both should be considered when planning in vitro experiments in the presence of flow. Understanding the individual and synergic effects of the two forces could provide important insights into physiological and pathological processes involved in vascular remodeling and adaptation. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
A Rotary Flow Channel for Shear Stress Sensor Calibration

NASA Technical Reports Server (NTRS)

Zuckerwar, Allan J.; Scott, Michael A.

2004-01-01

A proposed shear sensor calibrator consists of a rotating wheel with the sensor mounted tangential to the rim and positioned in close proximity to the rim. The shear stress generated by the flow at the sensor position is simply tau(sub omega) = (mu)r(omega)/h, where mu is the viscosity of the ambient gas, r the wheel radius, omega the angular velocity of the wheel, and h the width of the gap between the wheel rim and the sensor. With numerical values of mu = 31 (mu)Pa s (neon at room temperature), r = 0.5 m, omega = 754 /s (7200 rpm), and h = 50.8 m, a shear stress of tau(sub omega) = 231 Pa can be generated. An analysis based on one-dimensional flow, with the flow velocity having only an angular component as a function of the axial and radial coordinates, yields corrections to the above simple formula for the curvature of the wheel, flatness of the sensor, and finite width of the wheel. It is assumed that the sensor mount contains a trough (sidewalls) to render a velocity release boundary condition at the edges of the rim. The Taylor number under maximum flow conditions is found to be 62.3, sufficiently low to obviate flow instability. The fact that the parameters entering into the evaluation of the shear stress can be measured to high accuracy with well-defined uncertainties makes the proposed calibrator suitable for a physical standard for shear stress calibration.

FEM Modeling of In-Plane Stress Distribution in Thick Brittle Coatings/Films on Ductile Substrates Subjected to Tensile Stress to Determine Interfacial Strength

PubMed Central

Zhang, Fangzhou; Bordia, Rajendra K.

2018-01-01

The ceramic-metal interface is present in various material structures and devices that are vulnerable to failures, like cracking, which are typically due to their incompatible properties, e.g., thermal expansion mismatch. In failure of these multilayer systems, interfacial shear strength is a good measure of the robustness of interfaces, especially for planar films. There is a widely-used shear lag model and method by Agrawal and Raj to analyse and measure the interfacial shear strength of thin brittle film on ductile substrates. The use of this classical model for a type of polymer derived ceramic coatings (thickness ~18 μm) on steel substrate leads to high values of interfacial shear strength. Here, we present finite element simulations for such a coating system when it is subjected to in-plane tension. Results show that the in-plane stresses in the coating are non-uniform, i.e., varying across the thickness of the film. Therefore, they do not meet one of the basic assumptions of the classical model: uniform in-plane stress. Furthermore, effects of three significant parameters, film thickness, crack spacing, and Young’s modulus, on the in-plane stress distribution have also been investigated. ‘Thickness-averaged In-plane Stress’ (TIS), a new failure criterion, is proposed for estimating the interfacial shear strength, which leads to a more realistic estimation of the tensile strength and interfacial shear strength of thick brittle films/coatings on ductile substrates. PMID:29584647
Giant deviation of a relaxation time from generalized Newtonian theory in discontinuous shear thickening suspensions

NASA Astrophysics Data System (ADS)

Maharjan, Rijan; Brown, Eric

2017-12-01

We investigated the transient relaxation of a discontinuous shear thickening (DST) suspension of cornstarch in water. We performed two types of relaxation experiments starting from a steady shear in a parallel-plate rheometer, followed either by stopping the top plate rotation and measuring the transient torque relaxation or by removing the torque on the plate and measuring the transient rotation of the tool. We found that at low effective weight fraction ϕeff<58.8 ±0.4 % , the suspensions exhibited a relaxation behavior consistent with a generalized Newtonian fluid in which the relaxation is determined by the steady-state relationship between shear stress and shear rate. However, for larger weight fraction 58.8 %<ϕeff<61.0 % , near the liquid-solid transition ϕc=61.0 ±0.7 % , we found relaxation behaviors qualitatively and quantitatively different from the generalized Newtonian model. The regime where the relaxation was inconsistent with the generalized Newtonian model was the same where we found positive normal stress during relaxation, and in some cases we found an oscillatory response, suggestive of a solidlike structure consisting of a system-spanning contact network of particles. This regime also corresponds to the same packing fraction range where we consistently found discontinuous shear thickening in rate-controlled, steady-state measurements. The relaxation time in this range scales with the inverse of the critical shear rate at the onset of shear thickening, which may correspond to a contact relaxation time for nearby particles in the structure to flow away from each other. In this range, the relaxation time was the same in both stress- and rate-controlled relaxation experiments, indicating the relaxation time is more intrinsic than an effective viscosity in this range and is needed in addition to the steady-state viscosity function to describe transient flows. The discrepancy between the measured relaxation times and the generalized Newtonian prediction was found to be as large as four orders of magnitude, and extrapolations diverge in the limit as ϕeff→ϕc as the generalized Newtonian prediction approaches 0. This quantitative discrepancy indicates the relaxation is not controlled by the dissipative terms in the constitutive relation. At the highest weight fractions, the relaxation time scales were measured to be on the order of ˜1 s. The fact that this time scale is resolvable by the naked eye may be important to understanding some of the dynamic phenomenon commonly observed in cornstarch and water suspensions. We also showed that using the critical shear rate γ˙c at the onset of shear thickening to characterize the effective weight fraction ϕeff can more precisely characterize material properties near the critical point ϕc, allowing us to resolve this transition so close to ϕc. This conversion to ϕeff can also be used to compare experiments done in other laboratories or under different temperature and humidity conditions on a consistent ϕeff scale at our reference temperature and humidity environment.
Role of stresses in annealing of ion-implantation damage in Si

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seshan, K.; EerNisse, E.P.

Recent results showing a crystallographic orientation dependence of growth kinetics, secondary defects, and stress relief in annealing of ion-implanted Si are shown to be self-consistent if interpreted in terms of the influence of stresses upon annealing processes. The stress influence proposed is microplastic shear which is induced in (112) directions on (111) planes inclined to the implant surface by the biaxial stress created in the implant region by ion-implantation damage. The shear stresses are shown to be dependent on crystallographic orientation in a manner consistent with the model.
A comparison of simple shear characterization methods for composite laminates

NASA Technical Reports Server (NTRS)

Yeow, Y. T.; Brinson, H. F.

1978-01-01

Various methods for the shear stress/strain characterization of composite laminates are examined and their advantages and limitations are briefly discussed. Experimental results and the necessary accompanying analysis are then presented and compared for three simple shear characterization procedures. These are the off-axis tensile test method, the (+/- 45 deg)s tensile test method and the (0/90 deg)s symmetric rail shear test method. It is shown that the first technique indicates the shear properties of the graphite/epoxy laminates investigated are fundamentally brittle in nature while the latter two methods tend to indicate that these laminates are fundamentally ductile in nature. Finally, predictions of incrementally determined tensile stress/strain curves utilizing the various different shear behaviour methods as input information are presented and discussed.
A comparison of simple shear characterization methods for composite laminates

NASA Technical Reports Server (NTRS)

Yeow, Y. T.; Brinson, H. F.

1977-01-01

Various methods for the shear stress-strain characterization of composite laminates are examined, and their advantages and limitations are briefly discussed. Experimental results and the necessary accompanying analysis are then presented and compared for three simple shear characterization procedures. These are the off-axis tensile test method, the + or - 45 degs tensile test method and the 0 deg/90 degs symmetric rail shear test method. It is shown that the first technique indicates that the shear properties of the G/E laminates investigated are fundamentally brittle in nature while the latter two methods tend to indicate that the G/E laminates are fundamentally ductile in nature. Finally, predictions of incrementally determined tensile stress-strain curves utilizing the various different shear behavior methods as input information are presented and discussed.
Effects of hydraulic roughness on surface textures of gravel‐bed rivers

USGS Publications Warehouse

Buffington, John M.; Montgomery, David R.

1999-01-01

Field studies of forest gravel‐bed rivers in northwestern Washington and southeastern Alaska demonstrate that bed‐surface grain size is responsive to hydraulic roughness caused by bank irregularities, bars, and wood debris. We evaluate textural response by comparing reach‐average median grain size (D50) to that predicted from the total bank‐full boundary shear stress (т0bf), representing a hypothetical reference condition of low hydraulic roughness. For a given т0bf, channels with progressively greater hydraulic roughness have systematically finer bed surfaces, presumably due to reduced bed shear stress, resulting in lower channel competence and diminished bed load transport capacity, both of which promote textural fining. In channels with significant hydraulic roughness, observed values D50 can be up to 90% smaller than those predicted from т0bf. We find that wood debris plays an important role at our study sites, not only providing hydraulic roughness but also influencing pool spacing, frequency of textural patches, and the amplitude and wavelength of bank and bar topography and their consequent roughness. Our observations also have biological implications. We find that textural fining due to hydraulic roughness can create usable salmonid spawning gravels in channels that otherwise would be too coarse.
X-ray micro computed tomography for the visualization of an atherosclerotic human coronary artery

NASA Astrophysics Data System (ADS)

Matviykiv, Sofiya; Buscema, Marzia; Deyhle, Hans; Pfohl, Thomas; Zumbuehl, Andreas; Saxer, Till; Müller, Bert

2017-06-01

Atherosclerosis refers to narrowing or blocking of blood vessels that can lead to a heart attack, chest pain or stroke. Constricted segments of diseased arteries exhibit considerably increased wall shear stress, compared to the healthy ones. One of the possibilities to improve patient’s treatment is the application of nano-therapeutic approaches, based on shear stress sensitive nano-containers. In order to tailor the chemical composition and subsequent physical properties of such liposomes, one has to know precisely the morphology of critically stenosed arteries at micrometre resolution. It is often obtained by means of histology, which has the drawback of offering only two-dimensional information. Additionally, it requires the artery to be decalcified before sectioning, which might lead to deformations within the tissue. Micro computed tomography (μCT) enables the three-dimensional (3D) visualization of soft and hard tissues at micrometre level. μCT allows lumen segmentation that is crucial for subsequent flow simulation analysis. In this communication, tomographic images of a human coronary artery before and after decalcification are qualitatively and quantitatively compared. We analyse the cross section of the diseased human coronary artery before and after decalcification, and calculate the lumen area of both samples.
Use of non-fault fractures in stress tensor reconstruction using the Mohr Circle with the Win-tensor program

NASA Astrophysics Data System (ADS)

Delvaux, Damien

2016-04-01

Paleostress inversion of geological fault-slip data is usually done using the directional part of the applied stress tensor on a slip plane and comparing it with the observed slip lines. However, this method do not fully exploit the brittle data sets as those are composed of shear and tension fractures, in addition to faults. Brittle deformation can be decomposed in two steps. An initial fracture/failure in previously intact rock generate extension/tensile fractures or shear fractures, both without visible opening or displacement. This first step may or not be followed by fracture opening to form tension joints, frictional shearing to form shear faults, or a combination of opening and shearing which produces hybrid fractures. Fractured rock outcrop contain information of the stress conditions that acted during both brittle deformation steps. The purpose here is to investigate how the fracture pattern generated during the initial fracture/failure step might be used in paleostress reconstruction. Each fracture is represented on the Mohr Circle by its resolved normal and shear stress magnitudes. We consider the typical domains on the Mohr circle where the different types de fractures nucleate (tension, hybrid, shear and compression fractures), as well the domain which contain reactivated fractures (faults reactivating an initial fracture plane). In function of the fracture type defined in the field, a "distance" is computed on the Mohr circle between each point and its expected corresponding nucleation/reactivation domain. This "Mohr Distance" is then used as function to minimize during the inversion. We implemented this new function in the Win-Tensor program, and tested it with natural and synthetic data sets from different stress regimes. It can be used alone using only the Mohr Distance on each plane (function F10), or combined with the angular misfit between observed striae and resolved shear directions (composite function F11). When used alone (F10), only the 3 stress axes can be determined and the stress ratio R (sigma 2-3)/sigma1-3) has to be pre-determined. With the combined function (F11), it provide an additional constrain to the classical angular misfit. With data sets composed of a majority of neoformed fractures, stress inversion using the Mohr Distance F10 function provide a good approximation of the 3 stress axes (using only the fracture data) as compared with the results of the F11 composite function (using also the observed slip lines). Tensor program is available at (http://www.damiendelvaux.be/Tensor/tensor-index.html).
Material characterization of structural adhesives in the lap shear mode

NASA Technical Reports Server (NTRS)

Sancaktar, E.; Schenck, S. C.

1983-01-01

A general method for characterizing structual adhesives in the bonded lap shear mode is proposed. Two approaches in the form of semiempirical and theoretical approaches are used. The semiempirical approach includes Ludwik's and Zhurkov's equations to describe respectively, the failure stresses in the constant strain rate and constant stress loading modes with the inclusion of the temperature effects. The theoretical approach is used to describe adhesive shear stress-strain behavior with the use of viscoelastic or nonlinear elastic constitutive equations. Two different model adhesives are used in the single lap shear mode with titanium adherends. These adhesives (one of which was developed at NASA Langley Research Center) are currently considered by NASA for possible aerospace applications. Use of different model adhesives helps in assessment of the generality of the method.
Plastic deformation of silicon dendritic web ribbons during the growth

NASA Technical Reports Server (NTRS)

Cheng, L. J.; Dumas, K. A.; Su, B. M.; Leipold, M. H.

1984-01-01

The distribution of slip dislocations in silicon dendritic web ribbons due to plastic deformation during the cooling phase of the growth was studied. The results show the existence of two distinguishable stress regions across the ribbon formed during the plastic deformation stage, namely, shear stress at the ribbon edges and tensile stress at the middle. In addition, slip dislocations caused by shear stress near the edges appear to originate at the twin plane.
Constitutive law for the densification of fused silica with applications in polishing and microgrinding

NASA Astrophysics Data System (ADS)

Lambropoulos, John C.; Fang, Tong; Xu, Su; Gracewski, Sheryl M.

1995-09-01

We discuss a constitutive model describing the permanent densification of fused silica under large applied pressures and shear stresses. The constitutive law is assumed to be rate- independent, and uses a yield function coupling hydrostatic pressure and shear stress, a flow rule describing the evolution of permanent strains after initial densification, and a hardening rule describing the dependence of the incremental densification on the levels of applied stresses. The constitutive law accounts for multiaxial states of stress, since during polishing and grinding operations complex stress states occur in a thin surface layer due to the action of abrasive particles. Due to frictional and other abrasive forces, large shear stresses are present near the surface during manufacturing. We apply the constitutive law in estimating the extent of the densified layer during the mechanical interaction of an abrasive grain and a flat surface.
Nonlinear Reynolds stress model for turbulent shear flows

NASA Technical Reports Server (NTRS)

Barton, J. Michael; Rubinstein, R.; Kirtley, K. R.

1991-01-01

A nonlinear algebraic Reynolds stress model, derived using the renormalization group, is applied to equilibrium homogeneous shear flow and fully developed flow in a square duct. The model, which is quadratically nonlinear in the velocity gradients, successfully captures the large-scale inhomogeneity and anisotropy of the flows studied. The ratios of normal stresses, as well as the actual magnitudes of the stresses are correctly predicted for equilibrium homogeneous shear flow. Reynolds normal stress anisotropy and attendant turbulence driven secondary flow are predicted for a square duct. Profiles of mean velocity and normal stresses are in good agreement with measurements. Very close to walls, agreement with measurements diminishes. The model has the benefit of containing no arbitrary constants; all values are determined directly from the theory. It seems that near wall behavior is influenced by more than the large scale anisotropy accommodated in the current model. More accurate near wall calculations may well require a model for anisotropic dissipation.
Rheological properties of soil: a review

NASA Astrophysics Data System (ADS)

Zhu, Guangli; Zhu, Long; Yu, Chao

2017-05-01

Recently rheological methods have been applied to investigate the mechanical properties of soil micro-structure. Rheological techniques have a number of quantitative physically based measurements and offer a better understanding of how soil micro-structure behaves when subject to stress. Rheological material is refers to deformation properties similar to the solid and flow properties similar to the liquid of bound water and colloidal substances under stress. Soil rheology is divided into fluid rheology and plasticity rheology. Fluid rheology is produced by rheological material. Plasticity rheology mainly refers to the sliding and peristaltic between soil solid particles under shear stress. It is generally believed that the soft soil rheology mainly belongs to fluid rheology, while the rheology of sand and other coarse grained soil mainly belongs to plasticity rheology. Thus, rheology mechanisms of soft soil and sand are different. This paper introduces the methods of the research progress on the rheology of soil, in the soil rheological mechanism, rheological model and rheological numerical aspects of the research at home and abroad were summarized and analysed, discussed the problems existed in related research, and puts forward some suggestions for the future study on the rheology of soil.
Longitudinal shear behavior of several oxide dispersion strengthened alloys

NASA Technical Reports Server (NTRS)

Glasgow, T. K.

1978-01-01

Two commercial oxide dispersion strengthened (ODS) alloys, MA-753 and MA-754, and three experimental ODS alloys, MA-757E, MA-755E, and MA-6000E, were tested in shear at 760 C. Comparisons were made with other turbine blade and vane alloys. All of the ODS alloys exhibited less shear strength than directionally solidified Mar-M 200 = Hf or then conventionally cast B-1900. The strongest ODS alloy tested, MA-755E, was comparable in both shear and tensile strength to the lamellar directionally solidified eutectic alloy gamma/gamma prime - delta. Substantial improvements in shear resistance were found for all alloys tested when the geometry of the specimen was changed from one generating a transverse tensile stress in the shear area to one generating a transverse compressive stress. Finally, 760 C shear strength as a fraction of tensile strength was found to increase linearly with the log of the transverse tensile ductility.
Effects of fluid shear stress on polyelectrolyte multilayers by neutron scattering studies

DOE PAGES

Singh, Saurabh; Junghans, Ann; Watkins, Erik; ...

2015-02-17

The structure of layer-by-layer (LbL) deposited nanofilm coatings consists of alternating polyethylenimine (PEI) and polystyrenesulfonate (PSS) films deposited on a single crystal quartz substrate. LbL-deposited nanofilms were investigated by neutron reflectomery (NR) in contact with water in the static and fluid shear stress conditions. The fluid shear stress was applied through a laminar flow of the liquid parallel to the quartz/polymer interface in a custom-built solid–liquid interface cell. The scattering length density profiles obtained from NR results of these polyelectrolyte multilayers (PEM), measured under different shear conditions, showed proportional decrease of volume fraction of water hydrating the polymers. For themore » highest shear rate applied (ca. 6800 s –1) the water volume fraction decreased by approximately 7%. The decrease of the volume fraction of water was homogeneous through the thickness of the film. Since there were not any significant changes in the total polymer thickness, it resulted in negative osmotic pressures in the film. The PEM films were compared with the behavior of thin films of thermoresponsive poly(N-isopropylacrylamide) (pNIPAM) deposited via spin-coating. The PEM and pNIPAM differ in their interactions with water molecules, and they showed opposite behaviors under the fluid shear stress. In both cases the polymer hydration was reversible upon the restoration of static conditions. Furthermore, a theoretical explanation is given to explain this difference in the effect of shear on hydration of polymeric thin films.« less
A simple model for the prediction of the discrete stiffness states of a homogeneous electrostatically tunable multi-layer beam

NASA Astrophysics Data System (ADS)

Bergamini, A.; Christen, R.; Motavalli, M.

2007-04-01

The adaptive modification of the mechanical properties of structures has been described as a key to a number of new or enhanced technologies, ranging from prosthetics to aerospace applications. Previous work reported the electrostatic tuning of the bending stiffness of simple sandwich structures by modifying the shear stress transfer parameters at the interface between faces and the compliant core of the sandwich. For this purpose, the choice of a sandwich structure presented considerable experimental advantages, such as the ability to obtain a large increase in stiffness by activating just two interfaces between the faces and the core of the beam. The hypothesis the development of structures with tunable bending stiffness is based on, is that by applying a normal stress at the interface between two layers of a multi-layer structure it is possible to transfer shear stresses from one layer to the other by means of adhesion or friction forces. The normal stresses needed to generate adhesion or friction can be generated by an electrostatic field across a dielectric layer interposed between the layers of a structure. The shear stress in the cross section of the structure (e.g. a beam) subjected to bending forces is transferred in full, if sufficiently large normal stresses and an adequate friction coefficient at the interface are given. Considering beams with a homogeneous cross-section, in which all layers are made of the same material and have the same width, eliminates the need to consider parameters such as the shear modulus of the material and the shear stiffness of the core, thus making the modelling work easier and the results more readily understood. The goal of the present work is to describe a numerical model of a homogeneous multi-layer beam. The model is validated against analytical solutions for the extreme cases of interaction at the interface (no friction and a high level of friction allowing for full shear stress transfer). The obtained model is used to better understand the processes taking place at the interfaces between layers, demonstrate the existence of discrete stiffness states and to find guidance for the selection of suitable dielectric layers for the generation of the electrostatic normal stresses needed for the shear stress transfer at the interface.
Periodic Viscous Shear Heating Instability in Fine-Grained Shear Zones: Mechanism for Intermediate Depth Earthquakes

NASA Astrophysics Data System (ADS)

Coon, E.; Kelemen, P.; Hirth, G.; Spiegelman, M.

2005-12-01

Kelemen and Hirth (Fall 2004 AGU) presented a model for periodic, viscous shear heating instabilities along pre-existing, fine grained shear zones. This provides an attractive alternative to dehydration embrittlement for explaining intermediate-depth earthquakes, especially those in a narrow thermal window within the mantle section of subducting oceanic plates (Hacker et al JGR03). Ductile shear zones with widths of cm to m are common in shallow mantle massifs and peridotite along oceanic fracture zones. Pseudotachylites in a mantle shear zone show that shear heating temperatures exceeded the mantle solidus (Obata & Karato Tectonophys95). Olivine grain growth in shear zones is pinned by closely spaced pyroxenes; thus, once formed, these features do not `heal' on geological time scales in the absence of melt or fluid (Warren & Hirth EPSL05). Grain-size sensitive creep will be localized within these shear zones, in preference to host rocks with olivine grain size from 1 to 10 mm. Inspired by the work of Whitehead & Gans (GJRAS74), we proposed that such pre-existing shear zones might undergo repeated shear heating instabilities. This is not a new concept; what is new is that viscous deformation is limited to a narrow shear zone, because grain boundary sliding, sensitive to both stress and grain size, may accommodate creep even at high stress and high temperature. These new ideas yield a new result: simple models for a periodic shear heating instability. Last year, we presented a 1D numerical model using olivine flow laws, assuming that viscous deformation remains localized in shear zones, surrounded by host rocks undergoing elastic deformation. Stress evolves due to elastic strain and drives viscous deformation in a shear zone of specified width. Shear heating and thermal diffusion control T. A maximum of 1400 C (substantial melting of peridotite ) was imposed. Grain size evolves due to recrystallization and diffusion. For strain rates of E-13 to E-14 per sec and initial T of 600 to 850 C, this produced periodic viscous shear heating events with periods of 100's to 1000's of years. Strain rates during these events approach 1 per second as temperatures reach 1400. Cooling between events returns the shear zone almost to its initial temperature, though ultimately shear zone temperature between events exceeds 850 C resulting in stable viscous creep. Analysis shows that our system of equations jumps from one steady state to another, depending on a non-dimensional number relating the rate of shear heating to the rate of diffusive cooling. This year, Kelemen and Hirth show that the rate of stress drop during shear heating events is greater than the rate of elastic stress relaxation, so that shear heating events are a runaway instability. Rather than capping the temperature at 1400 C, we parameterize melt fraction as a function of T, and shear viscosity as a function of melt fraction. A problem with our 1D model is that predicted displacements are too large (1 to 20 m) during shear heating events, essentially because there is no resistance at shear zone ends. To address this, Coon and Spiegelman have embarked on a 3D model, incorporating a pre-existing fine-grained, tabular shear zone of finite extent, with a visco-elastic rheology for both shear zone and wall rocks. Preliminary 1D models using this approach show that the more complicated rheology yields the same result as the simpler model. We will present preliminary results, and determine the Maxwell time for this problem, since low strain rates could produce viscous relaxation in both shear zone and wall rocks with negligible shear heating.
Visualization of three pathways for macromolecule transport across cultured endothelium and their modification by flow.

PubMed

Ghim, Mean; Alpresa, Paola; Yang, Sung-Wook; Braakman, Sietse T; Gray, Stephen G; Sherwin, Spencer J; van Reeuwijk, Maarten; Weinberg, Peter D

2017-11-01

Transport of macromolecules across vascular endothelium and its modification by fluid mechanical forces are important for normal tissue function and in the development of atherosclerosis. However, the routes by which macromolecules cross endothelium, the hemodynamic stresses that maintain endothelial physiology or trigger disease, and the dependence of transendothelial transport on hemodynamic stresses are controversial. We visualized pathways for macromolecule transport and determined the effect on these pathways of different types of flow. Endothelial monolayers were cultured under static conditions or on an orbital shaker producing different flow profiles in different parts of the wells. Fluorescent tracers that bound to the substrate after crossing the endothelium were used to identify transport pathways. Maps of tracer distribution were compared with numerical simulations of flow to determine effects of different shear stress metrics on permeability. Albumin-sized tracers dominantly crossed the cultured endothelium via junctions between neighboring cells, high-density lipoprotein-sized tracers crossed at tricellular junctions, and low-density lipoprotein-sized tracers crossed through cells. Cells aligned close to the angle that minimized shear stresses across their long axis. The rate of paracellular transport under flow correlated with the magnitude of these minimized transverse stresses, whereas transport across cells was uniformly reduced by all types of flow. These results contradict the long-standing two-pore theory of solute transport across microvessel walls and the consensus view that endothelial cells align with the mean shear vector. They suggest that endothelial cells minimize transverse shear, supporting its postulated proatherogenic role. Preliminary data show that similar tracer techniques are practicable in vivo. NEW & NOTEWORTHY Solutes of increasing size crossed cultured endothelium through intercellular junctions, through tricellular junctions, or transcellularly. Cells aligned to minimize the shear stress acting across their long axis. Paracellular transport correlated with the level of this minimized shear, but transcellular transport was reduced uniformly by flow regardless of the shear profile. Copyright © 2017 the American Physiological Society.
Micromechanics of sea ice frictional slip from test basin scale experiments

NASA Astrophysics Data System (ADS)

Sammonds, Peter R.; Hatton, Daniel C.; Feltham, Daniel L.

2017-02-01

We have conducted a series of high-resolution friction experiments on large floating saline ice floes in an environmental test basin. In these experiments, a central ice floe was pushed between two other floes, sliding along two interfacial faults. The frictional motion was predominantly stick-slip. Shear stresses, normal stresses, local strains and slip displacement were measured along the sliding faults, and acoustic emissions were monitored. High-resolution measurements during a single stick-slip cycle at several positions along the fault allowed us to identify two phases of frictional slip: a nucleation phase, where a nucleation zone begins to slip before the rest of the fault, and a propagation phase when the entire fault is slipping. This is slip-weakening behaviour. We have therefore characterized what we consider to be a key deformation mechanism in Arctic Ocean dynamics. In order to understand the micromechanics of sea ice friction, we have employed a theoretical constitutive relation (i.e. an equation for shear stress in terms of temperature, normal load, acceleration, velocity and slip displacement) derived from the physics of asperity-asperity contact and sliding (Hatton et al. 2009 Phil. Mag. 89, 2771-2799 (doi:10.1080/14786430903113769)). We find that our experimental data conform reasonably with this frictional law once slip weakening is introduced. We find that the constitutive relation follows Archard's law rather than Amontons' law, with ? (where τ is the shear stress and σn is the normal stress) and n = 26/27, with a fractal asperity distribution, where the frictional shear stress, τ = ffractal Tmlws, where ffractal is the fractal asperity height distribution, Tml is the shear strength for frictional melting and lubrication and ws is the slip weakening. We can therefore deduce that the interfacial faults failed in shear for these experimental conditions through processes of brittle failure of asperities in shear, and, at higher velocities, through frictional heating, localized surface melting and hydrodynamic lubrication. This article is part of the themed issue 'Microdynamics of ice'.
STURM: Resuspension mesocosms with realistic bottom shear stress and water column turbulence for benthic-pelagic coupling studies: Design and Applications

NASA Astrophysics Data System (ADS)

Sanford, L. P.; Porter, E.; Porter, F. S.; Mason, R. P.

2016-02-01

Shear TUrbulence Resuspension Mesocosm (STURM) tanks, with high instantaneous bottom shear stress and realistic water column mixing in a single system, allow more realistic benthic-pelagic coupling studies that include sediment resuspension. The 1 m3 tanks can be programmed to produce tidal or episodic sediment resuspension over extended time periods (e.g. 4 weeks), over muddy sediments with or without infaunal organisms. The STURM tanks use a resuspension paddle that produces uniform bottom shear stress across the sediment surface while gently mixing a 1 m deep overlying water column. The STURM tanks can be programmed to different magnitudes, frequencies, and durations of bottom shear stress (and thus resuspension) with proportional water column turbulence levels over a wide range of mixing settings for benthic-pelagic coupling experiments. Over eight STURM calibration settings, turbulence intensity ranged from 0.55 to 4.52 cm s-1, energy dissipation rate from 0.0032 to 2.65 cm2 s-3, the average bottom shear stress from 0.0068 to 0.19 Pa, and the instantaneous bottom shear stress from 0.07 to 2.0 Pa. Mixing settings can be chosen as desired and/or varied over the experiment, based on the scientific question at hand. We have used the STURM tanks for four 4-week benthic-pelagic coupling ecosystem experiments with tidal resuspension with or without infaunal bivalves, for stepwise erosion experiments with and without infaunal bivalves, for experiments on oyster biodeposit resuspension, to mimic storms overlain on tidal resuspension, and for experiments on the effects of varying frequency and duration of resuspension on the release of sedimentary contaminants. The large size of the tanks allows water quality and particle measurements using standard oceanographic instrumentation. The realistic scale and complexity of the contained ecosystems has revealed indirect feedbacks and responses that are not observable in smaller, less complex experimental systems.

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