33 CFR 100.118 - Searsport Lobster Boat Races, Searsport Harbor, ME.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Searsport Lobster Boat Races, Searsport Harbor, ME. 100.118 Section 100.118 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Lobster Boat Races, Searsport Harbor, ME. (a) Regulated Area. The regulated area includes all waters of...

33 CFR 100.109 - Winter Harbor Lobster Boat Race, Winter Harbor, ME.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Winter Harbor Lobster Boat Race, Winter Harbor, ME. 100.109 Section 100.109 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Lobster Boat Race, Winter Harbor, ME. (a) Regulated area. The regulated area includes all waters of Winter...

33 CFR 100.903 - Harborfest Dragon Boat Race; South Haven, MI.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Harborfest Dragon Boat Race; South Haven, MI. 100.903 Section 100.903 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Dragon Boat Race; South Haven, MI. (a) Regulated Area. A regulated area is established to include all...

33 CFR 100.903 - Harborfest Dragon Boat Race; South Haven, MI.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Harborfest Dragon Boat Race; South Haven, MI. 100.903 Section 100.903 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Dragon Boat Race; South Haven, MI. (a) Regulated Area. A regulated area is established to include all...

33 CFR 100.903 - Harborfest Dragon Boat Race; South Haven, MI.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Harborfest Dragon Boat Race; South Haven, MI. 100.903 Section 100.903 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Dragon Boat Race; South Haven, MI. (a) Regulated Area. A regulated area is established to include all...

33 CFR 100.913 - ACORA Garwood Classic Offshore Race, Algonac, MI.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false ACORA Garwood Classic Offshore Race, Algonac, MI. 100.913 Section 100.913 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Classic Offshore Race, Algonac, MI. (a) Regulated Area. A regulated area is established to include all...

33 CFR 100.913 - ACORA Garwood Classic Offshore Race, Algonac, MI.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false ACORA Garwood Classic Offshore Race, Algonac, MI. 100.913 Section 100.913 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Classic Offshore Race, Algonac, MI. (a) Regulated Area. A regulated area is established to include all...

33 CFR 100.916 - Chris Craft Silver Cup Races, Algonac, MI.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Chris Craft Silver Cup Races, Algonac, MI. 100.916 Section 100.916 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... Races, Algonac, MI. (a) Regulated Area. A regulated area is established to include all waters of the St...

33 CFR 100.916 - Chris Craft Silver Cup Races, Algonac, MI.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Chris Craft Silver Cup Races, Algonac, MI. 100.916 Section 100.916 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... Races, Algonac, MI. (a) Regulated Area. A regulated area is established to include all waters of the St...

33 CFR 100.913 - ACORA Garwood Classic Offshore Race, Algonac, MI.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false ACORA Garwood Classic Offshore Race, Algonac, MI. 100.913 Section 100.913 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Classic Offshore Race, Algonac, MI. (a) Regulated Area. A regulated area is established to include all...

33 CFR 100.913 - ACORA Garwood Classic Offshore Race, Algonac, MI.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false ACORA Garwood Classic Offshore Race, Algonac, MI. 100.913 Section 100.913 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Classic Offshore Race, Algonac, MI. (a) Regulated Area. A regulated area is established to include all...

33 CFR 100.916 - Chris Craft Silver Cup Races, Algonac, MI.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Chris Craft Silver Cup Races, Algonac, MI. 100.916 Section 100.916 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... Races, Algonac, MI. (a) Regulated Area. A regulated area is established to include all waters of the St...

Kinetic chain contributions to elbow function and dysfunction in sports.

PubMed

Ben Kibler, W; Sciascia, Aaron

2004-10-01

The elbow functions in throwing and other athletic activities as a link in the kinetic chain of force development, regulation, and transfer. Efficient function, with maximal performance and minimal injury risk, requires optimum activation of all the link in the kinetic chain. Injury is often associated with alterations in force production or regulation capabilities in links that may be distant to the site of injury. Evaluation of injured athletes should include screening examinations for these areas, and treatment and conditioning should also include these areas.

76 FR 63191 - Sudanese Sanctions Regulations; Iranian Transactions Regulations

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-12

... of this general license, the term food does not include alcoholic beverages, cigarettes, gum, or... license, the term food does not include alcoholic beverages, cigarettes, gum, or fertilizer. (iii... licenses that authorize the exportation or reexportation of food to individuals and entities in an area of...

33 CFR 100.919 - International Bay City River Roar, Bay City, MI.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false International Bay City River Roar, Bay City, MI. 100.919 Section 100.919 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Bay City River Roar, Bay City, MI. (a) Regulated Area. A regulated area is established to include all...

33 CFR 100.919 - International Bay City River Roar, Bay City, MI.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false International Bay City River Roar, Bay City, MI. 100.919 Section 100.919 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Bay City River Roar, Bay City, MI. (a) Regulated Area. A regulated area is established to include all...

33 CFR 100.915 - St. Clair River Classic Offshore Race, St. Clair, MI.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false St. Clair River Classic Offshore Race, St. Clair, MI. 100.915 Section 100.915 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Classic Offshore Race, St. Clair, MI. (a) Regulated Area. A regulated area is established to include all...

33 CFR 100.915 - St. Clair River Classic Offshore Race, St. Clair, MI.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false St. Clair River Classic Offshore Race, St. Clair, MI. 100.915 Section 100.915 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Classic Offshore Race, St. Clair, MI. (a) Regulated Area. A regulated area is established to include all...

33 CFR 100.915 - St. Clair River Classic Offshore Race, St. Clair, MI.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false St. Clair River Classic Offshore Race, St. Clair, MI. 100.915 Section 100.915 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Classic Offshore Race, St. Clair, MI. (a) Regulated Area. A regulated area is established to include all...

33 CFR 100.915 - St. Clair River Classic Offshore Race, St. Clair, MI.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false St. Clair River Classic Offshore Race, St. Clair, MI. 100.915 Section 100.915 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Classic Offshore Race, St. Clair, MI. (a) Regulated Area. A regulated area is established to include all...

7 CFR 945.4 - Production area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Production area. 945.4 Section 945.4 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Production area. Production area means all territory included within Malheur County, Oregon, and the counties...

50 CFR 229.32 - Atlantic large whale take reduction plan regulations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... South Channel Restricted Trap/Pot Area where it overlaps with Lobster Management Area (LMA) 2 and the... Trap/Pot Area overlaps with Lobster Management Area (LMA) 2 and the Outer Cape LMA (as defined in the... Offshore Management Area 3 (including the area known as the Area 2/3 Overlap and Area 3/5 Overlap as...

33 CFR 165.1195 - Regulated Navigation Area; Humboldt Bay Bar Channel and Humboldt Bay Entrance Channel, Humboldt...

Code of Federal Regulations, 2010 CFR

2010-07-01

... Navigation Area (RNA) includes all navigable waters of the Humboldt Bay Bar Channel and the Humboldt Bay Entrance Channel, Humboldt Bay, California. (b) Definitions. As used in this section— COTP means the Captain of the Port as defined in Title 33, Code of Federal Regulations, Section 1.01-30 and 3.55-20...

33 CFR 165.1195 - Regulated Navigation Area; Humboldt Bay Bar Channel and Humboldt Bay Entrance Channel, Humboldt...

Code of Federal Regulations, 2011 CFR

2011-07-01

... Navigation Area (RNA) includes all navigable waters of the Humboldt Bay Bar Channel and the Humboldt Bay Entrance Channel, Humboldt Bay, California. (b) Definitions. As used in this section— COTP means the Captain of the Port as defined in Title 33, Code of Federal Regulations, Section 1.01-30 and 3.55-20...

33 CFR 165.1195 - Regulated Navigation Area; Humboldt Bay Bar Channel and Humboldt Bay Entrance Channel, Humboldt...

Code of Federal Regulations, 2012 CFR

2012-07-01

... Navigation Area (RNA) includes all navigable waters of the Humboldt Bay Bar Channel and the Humboldt Bay Entrance Channel, Humboldt Bay, California. (b) Definitions. As used in this section— COTP means the Captain of the Port as defined in Title 33, Code of Federal Regulations, Section 1.01-30 and 3.55-20...

33 CFR 165.1195 - Regulated Navigation Area; Humboldt Bay Bar Channel and Humboldt Bay Entrance Channel, Humboldt...

Code of Federal Regulations, 2013 CFR

2013-07-01

... Navigation Area (RNA) includes all navigable waters of the Humboldt Bay Bar Channel and the Humboldt Bay Entrance Channel, Humboldt Bay, California. (b) Definitions. As used in this section— COTP means the Captain of the Port as defined in Title 33, Code of Federal Regulations, Section 1.01-30 and 3.55-20...

33 CFR 165.1195 - Regulated Navigation Area; Humboldt Bay Bar Channel and Humboldt Bay Entrance Channel, Humboldt...

Code of Federal Regulations, 2014 CFR

2014-07-01

... Navigation Area (RNA) includes all navigable waters of the Humboldt Bay Bar Channel and the Humboldt Bay Entrance Channel, Humboldt Bay, California. (b) Definitions. As used in this section— COTP means the Captain of the Port as defined in Title 33, Code of Federal Regulations, Section 1.01-30 and 3.55-20...

7 CFR 947.4 - Production area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Production area. 947.4 Section 947.4 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Definitions § 947.4 Production area. Production area means and includes Modoc and Siskiyou Counties in the...

33 CFR 165.9 - Geographic application of limited and controlled access areas and regulated navigation areas.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., including the territorial sea to a seaward limit of 12 nautical miles from the baseline. (c) Security zones..., including the territorial sea to a seaward limit of 12 nautical miles from the baseline. (d) Naval vessel..., including the territorial sea to a seaward limit of 12 nautical miles from the baseline. [USCG-2001-9044, 68...

Certification of Compliance Audit Checklist for Hazardous Waste Container Storage Areas

EPA Pesticide Factsheets

Example of a Certification of Compliance Audit Checklist -- Container Storage, which includes a fillable table with areas to list requirements, federal regulations, descriptions, locations of information, and criteria met.

Improving the Recreational Fishery on Malmstrom Air Force Base

DTIC Science & Technology

2010-08-01

requirements of NEPA, Air Force Regulations, and all applicable laws and regulations. Pow Wow Park is a recreational site located in the east central area...fishing day. Three hundred juvenile brown trout (Salmo trutta) from the Montana Fish, Wildlife and Parks State Fish Hatchery in Lewistown, Montana are...have proposed numerous improvements to the Pow Wow Park recreational area, including site work and equipment installations to enhance fish and wildlife

7 CFR 905.13 - District.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... described as lying within Regulation Area II, and County Commissioner's Districts Four and Five of Volusia County. (d) Citrus District Four shall include the Counties of Manatee, Sarasota, Hardee, Highlands...

33 CFR 100.T01-0103 - Special Local Regulation; Extreme Sailing Series Boston; Boston Harbor; Boston, MA.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Sailing Series Boston; Boston Harbor; Boston, MA. 100.T01-0103 Section 100.T01-0103 Navigation and... NAVIGABLE WATERS § 100.T01-0103 Special Local Regulation; Extreme Sailing Series Boston; Boston Harbor... special local regulation area is designed to restrict vessel traffic, including all non-motorized vessels...

Computer simulation studies in fluid and calcium regulation and orthostatic intolerance

NASA Technical Reports Server (NTRS)

1985-01-01

The systems analysis approach to physiological research uses mathematical models and computer simulation. Major areas of concern during prolonged space flight discussed include fluid and blood volume regulation; cardiovascular response during shuttle reentry; countermeasures for orthostatic intolerance; and calcium regulation and bone atrophy. Potential contributions of physiologic math models to future flight experiments are examined.

48 CFR 52.236-10 - Operations and Storage Areas.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Operations and Storage....236-10 Operations and Storage Areas. As prescribed in 36.510, insert the following clause: Operations and Storage Areas (APR 1984) (a) The Contractor shall confine all operations (including storage of...

48 CFR 52.236-10 - Operations and Storage Areas.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Operations and Storage....236-10 Operations and Storage Areas. As prescribed in 36.510, insert the following clause: Operations and Storage Areas (APR 1984) (a) The Contractor shall confine all operations (including storage of...

48 CFR 52.236-10 - Operations and Storage Areas.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Operations and Storage....236-10 Operations and Storage Areas. As prescribed in 36.510, insert the following clause: Operations and Storage Areas (APR 1984) (a) The Contractor shall confine all operations (including storage of...

48 CFR 52.236-10 - Operations and Storage Areas.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Operations and Storage....236-10 Operations and Storage Areas. As prescribed in 36.510, insert the following clause: Operations and Storage Areas (APR 1984) (a) The Contractor shall confine all operations (including storage of...

48 CFR 52.236-10 - Operations and Storage Areas.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Operations and Storage....236-10 Operations and Storage Areas. As prescribed in 36.510, insert the following clause: Operations and Storage Areas (APR 1984) (a) The Contractor shall confine all operations (including storage of...

33 CFR 100.120 - Special Local Regulations; Marine Events Held in the Coast Guard Sector Northern New England...

Code of Federal Regulations, 2014 CFR

2014-07-01

... Race. • Sponsor: Friendship Lobster Boat Race Committee. • Date: A one day event during a weekend...: The regulated area includes all waters of Friendship Harbor, Maine within the following points (NAD 83...

‘Maybe they should regulate them quite strictly until they know the true dangers’: a focus group study exploring UK adolescents’ views on e‐cigarette regulation

PubMed Central

Trevisan, Filippo; Hilton, Shona

2016-01-01

Abstract Background and aims Regulation of electronic cigarettes has moved to the top of the addiction policy agenda, as demonstrated by the recent focus across the United Kingdom on introducing age‐of‐sale restrictions. However, the views of those affected by such regulation remain largely unexplored. This paper presents the first detailed qualitative exploration of adolescents’ perceptions of existing, and opinions about potential e‐cigarette regulation. Methods Sixteen focus groups, including a total of 83 teenagers between the ages of 14 and 17 years, were conducted in deprived, mixed and affluent urban areas in Scotland and England between November 2014 and February 2015. Transcripts were imported into Nivivo 10, coded thematically and analysed. Results Participants critically considered existing evidence and competing interests in regulatory debates and demonstrated sophisticated understanding of the advantages and disadvantages of regulation. They overwhelmingly supported strong e‐cigarette regulation and endorsed restrictions on sales to minors, marketing and e‐cigarette use in public places. Concern about potential health harms of e‐cigarette use and marketing increasing the acceptability of vaping and smoking led these adolescents to support regulation. Conclusions In focus group discussions, a sample of UK adolescents exposed to particular communications about e‐cigarettes supported strict regulation of e‐cigarettes, including banning sales to minors and use in indoor public areas. PMID:26948979

7 CFR 634.12 - Eligible project areas.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 6 2013-01-01 2013-01-01 false Eligible project areas. 634.12 Section 634.12 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE... related to agricultural nonpoint source pollutants, including sediment animal waste, irrigation return...

7 CFR 634.12 - Eligible project areas.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 6 2011-01-01 2011-01-01 false Eligible project areas. 634.12 Section 634.12 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE... related to agricultural nonpoint source pollutants, including sediment animal waste, irrigation return...

7 CFR 634.12 - Eligible project areas.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 6 2012-01-01 2012-01-01 false Eligible project areas. 634.12 Section 634.12 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE... related to agricultural nonpoint source pollutants, including sediment animal waste, irrigation return...

7 CFR 634.12 - Eligible project areas.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 6 2014-01-01 2014-01-01 false Eligible project areas. 634.12 Section 634.12 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE... related to agricultural nonpoint source pollutants, including sediment animal waste, irrigation return...

15 CFR 970.204 - Environmental and use conflict analysis.

Code of Federal Regulations, 2012 CFR

2012-01-01

... REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR EXPLORATION LICENSES... activities in the area, including the testing of integrated mining systems which simulate commercial recovery... baseline data or plans for acquiring them. The applicant may at his option delay submission of baseline and...

15 CFR 970.204 - Environmental and use conflict analysis.

Code of Federal Regulations, 2014 CFR

2014-01-01

... REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR EXPLORATION LICENSES... activities in the area, including the testing of integrated mining systems which simulate commercial recovery... baseline data or plans for acquiring them. The applicant may at his option delay submission of baseline and...

15 CFR 970.204 - Environmental and use conflict analysis.

Code of Federal Regulations, 2013 CFR

2013-01-01

... REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR EXPLORATION LICENSES... activities in the area, including the testing of integrated mining systems which simulate commercial recovery... baseline data or plans for acquiring them. The applicant may at his option delay submission of baseline and...

33 CFR 100.120 - Special Local Regulations; Marine Events Held in the Coast Guard Sector Northern New England...

Code of Federal Regulations, 2013 CFR

2013-07-01

... Races • Event Type: Power Boat Race. • Sponsor: Friendship Lobster Boat Race Committee. • Date: A one... regulated area includes all waters of Friendship Harbor, Maine within the following points (NAD 83): 43°57...

33 CFR 100.120 - Special Local Regulations; Marine Events Held in the Coast Guard Sector Northern New England...

Code of Federal Regulations, 2012 CFR

2012-07-01

... Races • Event Type: Power Boat Race. • Sponsor: Friendship Lobster Boat Race Committee. • Date: A one... regulated area includes all waters of Friendship Harbor, Maine within the following points (NAD 83): 43°57...

15 CFR 970.204 - Environmental and use conflict analysis.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR EXPLORATION LICENSES... activities in the area, including the testing of integrated mining systems which simulate commercial recovery... baseline data or plans for acquiring them. The applicant may at his option delay submission of baseline and...

15 CFR 970.204 - Environmental and use conflict analysis.

Code of Federal Regulations, 2011 CFR

2011-01-01

... REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR EXPLORATION LICENSES... activities in the area, including the testing of integrated mining systems which simulate commercial recovery... baseline data or plans for acquiring them. The applicant may at his option delay submission of baseline and...

7 CFR 966.7 - Handle.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE TOMATOES GROWN IN FLORIDA Order Regulating... to place fresh tomatoes, produced in the production area, in the current of commerce within the... include the transportation, sale or delivery of field-run tomatoes within the production area by the...

76 FR 15888 - Special Regulations; Areas of the National Park System, Cape Cod National Seashore

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-22

... the public of the regulatory change. The proposed rule follows an extensive environmental analysis... rule would implement the Cape Cod National Seashore Hunting Program Environmental Impact Statement of... posted without change to http://www.regulations.gov , including any personal information provided. For...

33 CFR 110.60 - Captain of the Port, New York.

Code of Federal Regulations, 2014 CFR

2014-07-01

... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.60 Captain of the Port, New York. (a) Western... Harbors before any mooring is placed in this special anchorage area. (3) Glen Island, East. All waters... includes this special anchorage area. (14) Little Neck Bay. All waters east of a line drawn from 40°47′39.4...

33 CFR 110.60 - Captain of the Port, New York.

Code of Federal Regulations, 2012 CFR

2012-07-01

... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.60 Captain of the Port, New York. (a) Western... Harbors before any mooring is placed in this special anchorage area. (3) Glen Island, East. All waters... includes this special anchorage area. (14) Little Neck Bay. All waters east of a line drawn from 40°47′39.4...

33 CFR 110.60 - Captain of the Port, New York.

Code of Federal Regulations, 2013 CFR

2013-07-01

... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.60 Captain of the Port, New York. (a) Western... Harbors before any mooring is placed in this special anchorage area. (3) Glen Island, East. All waters... includes this special anchorage area. (14) Little Neck Bay. All waters east of a line drawn from 40°47′39.4...

Neuroanatomy of melanocortin-4 receptor pathway in the lateral hypothalamic area

PubMed Central

Cui, Huxing; Sohn, Jong-Woo; Gautron, Laurent; Funahashi, Hisayuki; Williams, Kevin W.; Elmquist, Joel K.; Lutter, Michael

2013-01-01

The central melanocortin system regulates body energy homeostasis including the melanocortin-4 receptor (MC4R). The lateral hypothalamic area (LHA) receives dense melanocortinergic inputs from the arcuate nucleus of hypothalamus and regulates multiple processes including food intake, reward behaviors and autonomic function. Using a mouse line in which green fluorescent protein (GFP) is expressed under control of MC4R gene promoter, we systemically investigated MC4R signaling in the LHA by combining double immunohistochemistry, electrophysiology and retrograde tracing techniques. We found that LHA MC4R-GFP neurons co-express neurotensin as well as the leptin receptor but not with other peptide neurotransmitters found in the LHA including orexin, melanin concentrating hormone and nesfatin-1. Furthermore, electrophysiological recording demonstrated that leptin, but not the MC4R agonist melanotan II, hyperpolarizes the majority of LHA MC4R-GFP neurons in an ATP-sensitive potassium channel-dependent manner. Retrograde tracing revealed that LHA MC4R-GFP neurons do not project to the ventral tegmental area, dorsal raphe nucleus, nucleus accumbens and spinal cord, and only limited number of neurons project to the nucleus of solitary tract and parabrachial nucleus. Our findings provide new insight into MC4R signaling in the LHA and its potential implication in homeostatic regulation of body energy balance. PMID:22605619

Psychological and neural contributions to appetite self-regulation.

PubMed

Stoeckel, Luke E; Birch, Leann L; Heatherton, Todd; Mann, Traci; Hunter, Christine; Czajkowski, Susan; Onken, Lisa; Berger, Paige K; Savage, Cary R

2017-03-01

This paper reviews the state of the science on psychological and neural contributions to appetite self-regulation in the context of obesity. Three content areas (neural systems and cognitive functions; parenting and early childhood development; and goal setting and goal striving) served to illustrate different perspectives on the psychological and neural factors that contribute to appetite dysregulation in the context of obesity. Talks were initially delivered at an NIH workshop consisting of experts in these three content areas, and then content areas were further developed through a review of the literature. Self-regulation of appetite involves a complex interaction between multiple domains, including cognitive, neural, social, and goal-directed behaviors and decision-making. Self-regulation failures can arise from any of these factors, and the resulting implications for obesity should be considered in light of each domain. In some cases, self-regulation is amenable to intervention; however, this does not appear to be universally true, which has implications for both prevention and intervention efforts. Appetite regulation is a complex, multifactorial construct. When considering its role in the obesity epidemic, it is advisable to consider its various dimensions together to best inform prevention and treatment efforts. © 2017 The Obesity Society.

Psychological and Neural Contributions to Appetite Self-Regulation

PubMed Central

Stoeckel, Luke E.; Birch, Leann L.; Heatherton, Todd; Mann, Traci; Hunter, Christine; Czajkowski, Susan; Onken, Lisa; Berger, Paige K.; Savage, Cary R.

2017-01-01

Objective Review the state-of-the-science on psychological and neural contributions to appetite self-regulation in the context of obesity. Methods Three content areas (neural systems and cognitive functions; parenting and early childhood development; and goal setting and goal striving) served as examples of different perspectives on the psychological and neural factors that contribute to appetite dysregulation in the context of obesity. Talks were initially delivered at a workshop consisting of experts in these three content areas and then content areas were further developed through a review of the literature. Results Self-regulation of appetite involves a complex interaction between multiple domains, including cognitive, neural, social, and goal-directed behaviors and decision-making. Self-regulation failures can results from any of these factors, and the resulting implications for obesity should be considered in light of each domain. In some cases, self-regulation appears to be amenable to intervention; however, this does not appear to be universally true, which has implications for both prevention and intervention efforts. Conclusions Appetite regulation is a complex, multi-factorial construct. When considering its role in the obesity epidemic, it is advisable to consider these various contributions together to best inform prevention and treatment efforts. PMID:28229541

'Maybe they should regulate them quite strictly until they know the true dangers': a focus group study exploring UK adolescents' views on e-cigarette regulation.

PubMed

Weishaar, Heide; Trevisan, Filippo; Hilton, Shona

2016-09-01

Regulation of electronic cigarettes has moved to the top of the addiction policy agenda, as demonstrated by the recent focus across the United Kingdom on introducing age-of-sale restrictions. However, the views of those affected by such regulation remain largely unexplored. This paper presents the first detailed qualitative exploration of adolescents' perceptions of existing, and opinions about potential e-cigarette regulation. Sixteen focus groups, including a total of 83 teenagers between the ages of 14 and 17 years, were conducted in deprived, mixed and affluent urban areas in Scotland and England between November 2014 and February 2015. Transcripts were imported into Nivivo 10, coded thematically and analysed. Participants critically considered existing evidence and competing interests in regulatory debates and demonstrated sophisticated understanding of the advantages and disadvantages of regulation. They overwhelmingly supported strong e-cigarette regulation and endorsed restrictions on sales to minors, marketing and e-cigarette use in public places. Concern about potential health harms of e-cigarette use and marketing increasing the acceptability of vaping and smoking led these adolescents to support regulation. In focus group discussions, a sample of UK adolescents exposed to particular communications about e-cigarettes supported strict regulation of e-cigarettes, including banning sales to minors and use in indoor public areas. © 2016 The Authors. Addiction published by John Wiley & Sons Ltd on behalf of Society for the Study of Addiction.

Y-12 Industrial Landfill V. Permit application modifications

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-09-01

This report contains the modifications in operations and design to meet the Tennessee Department of Environment and Conversation (TDEC) July 10, 1993, amendments to the regulations for Class 2 landfills. These modifications, though extensive in design and construction cost, are considered minor revisions and should not require a processing fee. Area 1 of ILF V, comprising approximately 20% of the ILF V footprint, was designed and submitted to TDEC prior to the implementation of current regulations. This initial area was constructed with a compacted clay liner and leachate collection system, and became operational in April 1994. The current regulations requiremore » landfills to have a composite liner with leachate collection system and closure cap. Modifications to upgrade Areas 2 and 3 of ILF V to meet the current TDEC requirements are included.« less

Neurofeedback of visual food cue reactivity: a potential avenue to alter incentive sensitization and craving.

PubMed

Ihssen, Niklas; Sokunbi, Moses O; Lawrence, Andrew D; Lawrence, Natalia S; Linden, David E J

2017-06-01

FMRI-based neurofeedback transforms functional brain activation in real-time into sensory stimuli that participants can use to self-regulate brain responses, which can aid the modification of mental states and behavior. Emerging evidence supports the clinical utility of neurofeedback-guided up-regulation of hypoactive networks. In contrast, down-regulation of hyperactive neural circuits appears more difficult to achieve. There are conditions though, in which down-regulation would be clinically useful, including dysfunctional motivational states elicited by salient reward cues, such as food or drug craving. In this proof-of-concept study, 10 healthy females (mean age = 21.40 years, mean BMI = 23.53) who had fasted for 4 h underwent a novel 'motivational neurofeedback' training in which they learned to down-regulate brain activation during exposure to appetitive food pictures. FMRI feedback was given from individually determined target areas and through decreases/increases in food picture size, thus providing salient motivational consequences in terms of cue approach/avoidance. Our preliminary findings suggest that motivational neurofeedback is associated with functionally specific activation decreases in diverse cortical/subcortical regions, including key motivational areas. There was also preliminary evidence for a reduction of hunger after neurofeedback and an association between down-regulation success and the degree of hunger reduction. Decreasing neural cue responses by motivational neurofeedback may provide a useful extension of existing behavioral methods that aim to modulate cue reactivity. Our pilot findings indicate that reduction of neural cue reactivity is not achieved by top-down regulation but arises in a bottom-up manner, possibly through implicit operant shaping of target area activity.

Tropical dry forest trees and lianas differ in leaf economic spectrum traits but have overlapping water-use strategies.

PubMed

Werden, Leland K; Waring, Bonnie G; Smith-Martin, Christina M; Powers, Jennifer S

2018-04-01

Tree species in tropical dry forests employ a wide range of strategies to cope with seasonal drought, including regulation of hydraulic function. However, it is uncertain if co-occurring lianas also possess a diversity of strategies. For a taxonomically diverse group of 14 tree and 7 liana species, we measured morphological and hydraulic functional traits during an unusual drought and under non-drought conditions to determine (i) if trees have different water-use strategies than lianas and (ii) if relationships among these traits can be used to better understand how tree and liana species regulate diurnal leaf water potential (Ψdiurnal). In this Costa Rican tropical dry forest, lianas and trees had overlapping water-use strategies, but differed in many leaf economic spectrum traits. Specifically, we found that both lianas and trees employed a diversity of Ψdiurnal regulation strategies, which did not differ statistically. However, lianas and trees did significantly differ in terms of certain traits including leaf area, specific leaf area, petiole length, wood vessel diameter and xylem vessel density. All liana and tree species we measured fell along a continuum of isohydric (partial) to anisohydric (strict or extreme) Ψdiurnal regulation strategies, and leaf area, petiole length, stomatal conductance and wood vessel diameter correlated with these strategies. These findings contribute to a trait-based understanding of how plants regulate Ψdiurnal under both drought stress and sufficient water availability, and underscore that lianas and trees employ a similarly wide range of Ψdiurnal regulation strategies, despite having vastly different growth forms.

45 CFR 1302.10 - Selection among applicants.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., including the opportunities provided for employment of target area residents and career development for....10 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT... comprehensive child development services at the community level, including the administrative and fiscal...

Mathematical modeling of fluid-electrolyte alterations during weightlessness

NASA Technical Reports Server (NTRS)

Leonard, J. I.

1984-01-01

Fluid electrolyte metabolism and renal endocrine control as it pertains to adaptation to weightlessness were studied. The mathematical models that have been particularly useful are discussed. However, the focus of the report is on the physiological meaning of the computer studies. A discussion of the major ground based analogs of weightlessness are included; for example, head down tilt, water immersion, and bed rest, and a comparison of findings. Several important zero g phenomena are described, including acute fluid volume regulation, blood volume regulation, circulatory changes, longer term fluid electrolyte adaptations, hormonal regulation, and body composition changes. Hypotheses are offered to explain the major findings in each area and these are integrated into a larger hypothesis of space flight adaptation. A conceptual foundation for fluid electrolyte metabolism, blood volume regulation, and cardiovascular regulation is reported.

[Regulation framework of watershed landscape pattern for non-point source pollution control based on 'source-sink' theory: A case study in the watershed of Maluan Bay, Xiamen City, China].

PubMed

Huang, Ning; Wang, Hong Ying; Lin, Tao; Liu, Qi Ming; Huang, Yun Feng; Li, Jian Xiong

2016-10-01

Watershed landscape pattern regulation and optimization based on 'source-sink' theory for non-point source pollution control is a cost-effective measure and still in the exploratory stage. Taking whole watershed as the research object, on the basis of landscape ecology, related theories and existing research results, a regulation framework of watershed landscape pattern for non-point source pollution control was developed at two levels based on 'source-sink' theory in this study: 1) at watershed level: reasonable basic combination and spatial pattern of 'source-sink' landscape was analyzed, and then holistic regulation and optimization method of landscape pattern was constructed; 2) at landscape patch level: key 'source' landscape was taken as the focus of regulation and optimization. Firstly, four identification criteria of key 'source' landscape including landscape pollutant loading per unit area, landscape slope, long and narrow transfer 'source' landscape, pollutant loading per unit length of 'source' landscape along the riverbank were developed. Secondly, nine types of regulation and optimization methods for different key 'source' landscape in rural and urban areas were established, according to three regulation and optimization rules including 'sink' landscape inlay, banding 'sink' landscape supplement, pollutants capacity of original 'sink' landscape enhancement. Finally, the regulation framework was applied for the watershed of Maluan Bay in Xiamen City. Holistic regulation and optimization mode of watershed landscape pattern of Maluan Bay and key 'source' landscape regulation and optimization measures for the three zones were made, based on GIS technology, remote sensing images and DEM model.

33 CFR 165.830 - Regulated Navigation Area; Reporting Requirements for Barges Loaded with Certain Dangerous...

Code of Federal Regulations, 2010 CFR

2010-07-01

... barges in the RNA must report the information required by this section as set out in table 165.830(g) of... navigation area (RNA): the Mississippi River above mile 235.0, Above Head of Passes, including all its... vessel operators and fleeting area managers responsible for CDC barges in the RNA. This section does not...

33 CFR 165.830 - Regulated Navigation Area; Reporting Requirements for Barges Loaded with Certain Dangerous...

Code of Federal Regulations, 2013 CFR

2013-07-01

... barges in the RNA must report the information required by this section as set out in table 165.830(g) of... navigation area (RNA): the Mississippi River above mile 235.0, Above Head of Passes, including all its... vessel operators and fleeting area managers responsible for CDC barges in the RNA. This section does not...

33 CFR 165.830 - Regulated Navigation Area; Reporting Requirements for Barges Loaded with Certain Dangerous...

Code of Federal Regulations, 2014 CFR

2014-07-01

... barges in the RNA must report the information required by this section as set out in table 165.830(g) of... navigation area (RNA): the Mississippi River above mile 235.0, Above Head of Passes, including all its... vessel operators and fleeting area managers responsible for CDC barges in the RNA. This section does not...

33 CFR 165.830 - Regulated Navigation Area; Reporting Requirements for Barges Loaded with Certain Dangerous...

Code of Federal Regulations, 2012 CFR

2012-07-01

... barges in the RNA must report the information required by this section as set out in table 165.830(g) of... navigation area (RNA): the Mississippi River above mile 235.0, Above Head of Passes, including all its... vessel operators and fleeting area managers responsible for CDC barges in the RNA. This section does not...

33 CFR 165.830 - Regulated Navigation Area; Reporting Requirements for Barges Loaded with Certain Dangerous...

Code of Federal Regulations, 2011 CFR

2011-07-01

... barges in the RNA must report the information required by this section as set out in table 165.830(g) of... navigation area (RNA): the Mississippi River above mile 235.0, Above Head of Passes, including all its... vessel operators and fleeting area managers responsible for CDC barges in the RNA. This section does not...

NOx control techniques for the CPI

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lambert, D.; McGowan, T.F.

1996-06-01

After years of air pollution control innovation, the control of emissions of nitrogen oxide compounds stands out as an area where much work remains to be performed in the chemical process industries (CPI). Federal regulations, ozone non-attainment areas, acid rain provisions of the US Clean Air Act, and corporate goals for emission reductions are all motivators. Primary CPI sources are high-temperature combustion systems, including fired heaters, boilers and Kilns. Nitrogen-based processes such as nitric acid manufacture also contribute. The paper discusses the regulations which define the problem and some solutions. These include fuel switching, low-excess air burners, fluegas recirculation, stagedmore » combustion, out of service burners, and wet scrubbing of flue gas. The paper briefly discusses costs of these options.« less

75 FR 952 - Draft Marine Sanitation Device Discharge Regulations for the Florida Keys National Marine...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-07

... supports over 6,000 species of plants, fishes, and invertebrates, including the Nation's only living coral reef that lies adjacent to the continent. The area includes one of the largest seagrass communities in...

7 CFR 1.427 - Filing; identification of parties of record; service; and computation of time.

Code of Federal Regulations, 2010 CFR

2010-01-01

... ADMINISTRATIVE REGULATIONS Rules of Practice Governing Adjudication of Sourcing Area Applications and Formal Review of Sourcing Areas Pursuant to the Forest Resources Conservation and Shortage Relief Act of 1990... officer or employee. (e) Computations of time. Saturdays, Sundays and Federal holidays shall be included...

Facility Programming and Construction Criteria [Planning Guide]. 702 KAR 4:170.

ERIC Educational Resources Information Center

Kentucky State Dept. of Education, Frankfort. Div. of Facilities Management.

This facility construction planning guide presents the minimum instructional space standards for Kentucky's public school system. It provides definitions of terms found in the regulations; presents space requirements for every type of instructional space within a public school, including circulation areas, storage, and mechanical/electrical areas;…

Mapping the World's Marine Protected and Managed Areas - Promoting Awareness, Compliance, and Enforcement via Open Data and Tools.

NASA Astrophysics Data System (ADS)

Vincent, T.; Zetterlind, V.; Tougher, B.

2016-12-01

Marine Protected and Managed Areas (MPAs) are a cornerstone of coastal and ocean conservation efforts and reflect years of dedicated effort to protect species and habitats through science-based regulation. When they are effective, biomass increases dramatically, and up to 14 fold and play a significant role in conserving biodiversity. Effective MPAs have enforcement. Enforcement cannot occur without awareness of their location among ocean stakeholders and the general public. The Anthropocene Institute, in partnership with the NOAA Marine Protected Area Center, is creating an actively managed, free and open, worldwide database of MPAs, including normalized metadata and regulation summaries, full GIS boundaries, revision history, and public facing interactive web maps. This project employs 2 full-time lawyers that first comb the relevant regulation; 2 full-time geographers and a full-time GIS database/web engineer.

7 CFR 301.52-2a - Regulated areas; suppressive and generally infested areas.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Regulated areas; suppressive and generally infested areas. 301.52-2a Section 301.52-2a Agriculture Regulations of the Department of Agriculture (Continued... Bollworm Quarantine and Regulations § 301.52-2a Regulated areas; suppressive and generally infested areas...

7 CFR 301.52-2a - Regulated areas; suppressive and generally infested areas.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 5 2014-01-01 2014-01-01 false Regulated areas; suppressive and generally infested areas. 301.52-2a Section 301.52-2a Agriculture Regulations of the Department of Agriculture (Continued... Bollworm Quarantine and Regulations § 301.52-2a Regulated areas; suppressive and generally infested areas...

7 CFR 301.52-2a - Regulated areas; suppressive and generally infested areas.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 5 2012-01-01 2012-01-01 false Regulated areas; suppressive and generally infested areas. 301.52-2a Section 301.52-2a Agriculture Regulations of the Department of Agriculture (Continued... Bollworm Quarantine and Regulations § 301.52-2a Regulated areas; suppressive and generally infested areas...

7 CFR 301.52-2a - Regulated areas; suppressive and generally infested areas.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 5 2013-01-01 2013-01-01 false Regulated areas; suppressive and generally infested areas. 301.52-2a Section 301.52-2a Agriculture Regulations of the Department of Agriculture (Continued... Bollworm Quarantine and Regulations § 301.52-2a Regulated areas; suppressive and generally infested areas...

7 CFR 301.52-2a - Regulated areas; suppressive and generally infested areas.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 5 2011-01-01 2011-01-01 false Regulated areas; suppressive and generally infested areas. 301.52-2a Section 301.52-2a Agriculture Regulations of the Department of Agriculture (Continued... Bollworm Quarantine and Regulations § 301.52-2a Regulated areas; suppressive and generally infested areas...

Regulated and Unregulated Fibrous Amphiboles of the Franciscan Formation Found in the Greater San Francisco Bay Area

NASA Astrophysics Data System (ADS)

Bailey, R.

2012-12-01

The San Francisco Bay Area is underlain in numerous locales by rocks of the Franciscan Formation, a significant number of which contain amphibole minerals which may occur in a fibrous or asbestiform habit. Such rocks include altered mafic volcanic rocks, serpentine complexes and high pressure metamorphic rocks (e.g. green schist, blue schist, amphibolite, eclogite, etc.). Although it is commonly known that actinolite/tremolite may occur within these rock bodies, it is also true that all of the other "regulated" amphiboles (riebeckite (crocidolite), amosite (grunerite) and anthophyllite, have been identified as well. In addition, a considerable number of other "non-regulated" amphiboles with a fibrous or asbestiform habit have been identified including: glaucophane, winchite, richterite, "Libby amphibole", hornblende, barroisite, cummingtonite and others. Extensive solid solution exists between many of these amphiboles which can make definitive identification difficult. Also, the possibility of complex pressure-temperature paths for these rocks means a single amphibole fiber/crystal can exhibit zonation of, and/or intergrowths between, multiple amphibole phases. It is important that regulators and laboratories are aware of the potential presence of these amphibole minerals, and possibly others, in rock and soil found in the San Francisco Bay Area and that they are not automatically discarded from asbestos fiber counts when they are observed. Criteria for identifying the amphiboles discussed above will be presented.

Corporate Structure Events Involving Regulated Utilities: The Need for a Multidisciplinary, Multijurisdictional Approach

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hempling, Scott

2006-08-15

The repeal of PUHCA has occasioned important questions on the appropriate role for regulation in the area of utility corporate structure, including complex process and jurisdictional issues. There is a disproportionality between the importance of these questions and the lack of attention that has been given them by our regulatory and political communities. (author)

Family Distance Regulation and School Engagement in Middle-School-Aged Children

ERIC Educational Resources Information Center

Bartle-Haring, Suzanne; Younkin, Felisha Lotspeich; Day, Randal

2012-01-01

The purpose of this study was to explore how family distance regulation and other family demographic factors influence parenting behavior and family routines, which, in turn, influences the child's school engagement. The data from the project came from a larger study conducted in a large Northwestern urban area and included both two-parent and…

44 CFR 9.4 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... includes those wetlands areas separated from their natural supply of water as a result of activities such... use, including, but not limited to, water and related land resources, planning, regulating and... which produce, use or store highly volatile, flammable, explosive, toxic or water-reactive materials; (b...

Screening procedure to evaluate effects of air pollution on Eastern Region wildernesses cited as Class I air quality areas.

Treesearch

Mary Beth Adams; Dale S. Nichols; Anthony C. Federer; Keith F. Jensen; Harry Parrott

1991-01-01

The USDA Forest Service's Eastern Region manages eight wilderness areas that have been designated as Class I air quality areas by the Federal Clean Air Act. As part of this legislation, Federal land managers are required to consult with air pollution regulators on the potential impacts of proposed air pollution emissions--including phytotoxic gases and acidic...

Gene Editing of Microalgae: Scientific Progress and Regulatory Challenges in Europe

PubMed Central

Spicer, Andrew

2018-01-01

It is abundantly clear that the development of gene editing technologies, represents a potentially powerful force for good with regard to human and animal health and addressing the challenges we continue to face in a growing global population. This now includes the development of approaches to modify microalgal strains for potential improvements in productivity, robustness, harvestability, processability, nutritional composition, and application. The rapid emergence and ongoing developments in this area demand a timely review and revision of the current definitions and regulations around genetically modified organisms (GMOs), particularly within Europe. Current practices within the EU provide exemptions from the GMO directives for organisms, including crop plants and micro-organisms that are produced through chemical or UV/radiation mutagenesis. However, organisms generated through gene editing, including microalgae, where only genetic changes in native genes are made, remain currently under the GMO umbrella; they are, as such, excluded from practical and commercial opportunities in the EU. In this review, we will review the advances that are being made in the area of gene editing in microalgae and the impact of regulation on commercial advances in this area with consideration to the current regulatory framework as it relates to GMOs including GM microalgae in Europe. PMID:29509719

Gene Editing of Microalgae: Scientific Progress and Regulatory Challenges in Europe.

PubMed

Spicer, Andrew; Molnar, Attila

2018-03-06

It is abundantly clear that the development of gene editing technologies, represents a potentially powerful force for good with regard to human and animal health and addressing the challenges we continue to face in a growing global population. This now includes the development of approaches to modify microalgal strains for potential improvements in productivity, robustness, harvestability, processability, nutritional composition, and application. The rapid emergence and ongoing developments in this area demand a timely review and revision of the current definitions and regulations around genetically modified organisms (GMOs), particularly within Europe. Current practices within the EU provide exemptions from the GMO directives for organisms, including crop plants and micro-organisms that are produced through chemical or UV/radiation mutagenesis. However, organisms generated through gene editing, including microalgae, where only genetic changes in native genes are made, remain currently under the GMO umbrella; they are, as such, excluded from practical and commercial opportunities in the EU. In this review, we will review the advances that are being made in the area of gene editing in microalgae and the impact of regulation on commercial advances in this area with consideration to the current regulatory framework as it relates to GMOs including GM microalgae in Europe.

Neuroanatomy of melanocortin-4 receptor pathway in the lateral hypothalamic area.

PubMed

Cui, Huxing; Sohn, Jong-Woo; Gautron, Laurent; Funahashi, Hisayuki; Williams, Kevin W; Elmquist, Joel K; Lutter, Michael

2012-12-15

The central melanocortin system regulates body energy homeostasis including the melanocortin-4 receptor (MC4R). The lateral hypothalamic area (LHA) receives dense melanocortinergic inputs from the arcuate nucleus of the hypothalamus and regulates multiple processes including food intake, reward behaviors, and autonomic function. By using a mouse line in which green fluorescent protein (GFP) is expressed under control of the MC4R gene promoter, we systemically investigated MC4R signaling in the LHA by combining double immunohistochemistry, electrophysiology, and retrograde tracing techniques. We found that LHA MC4R-GFP neurons coexpress neurotensin as well as the leptin receptor but do not coexpress other peptide neurotransmitters found in the LHA including orexin, melanin-concentrating hormone, and nesfatin-1. Furthermore, electrophysiological recording demonstrated that leptin, but not the MC4R agonist melanotan II, hyperpolarizes the majority of LHA MC4R-GFP neurons in an ATP- sensitive potassium channel-dependent manner. Retrograde tracing revealed that LHA MC4R-GFP neurons do not project to the ventral tegmental area, dorsal raphe nucleus, nucleus accumbens, and spinal cord, and only limited number of neurons project to the nucleus of the solitary tract and parabrachial nucleus. Our findings provide new insights into MC4R signaling in the LHA and its potential implications in homeostatic regulation of body energy balance. Copyright © 2012 Wiley Periodicals, Inc.

[Working verbally and non-verbally within the psychotherapeutic process].

PubMed

Weber-Steinbach, Reinhard; Tasche, Jens

2012-01-01

Patients in paediatric and adolescent psychiatry frequently suffer from both a categorical psychiatric disorder and structural deficits. Within the scope of a competence profile--which is subdivided into three areas: knowledge, skills, and a method--this article describes the term "structure" as used in the Operationalised Psychodynamic Diagnostics for Children and Adolescents (German abbreviation: OPD-KJ) as well as the deficits of self-esteem regulation. In this context, the development and importance of affects and their regulation for, as well as within, the therapeutic relationship are discussed, including the bodily processes associated with them. Finally, the article demonstrates how we as practitioners in the areas of therapeutic mental health and education can compensate for structural deficits of our patients by using our knowledge of psychological structures and of affect regulation and its importance for the therapeutic process; we can also use our own structural competences and competences to perceive the patients' affects as revealed by their bodies. For this purpose, we introduce methods that include body-psychotherapeutic interventions, among others.

47 CFR 20.6 - CMRS spectrum aggregation limit.

Code of Federal Regulations, 2014 CFR

2014-10-01

... the broadband PCS, cellular, or SMR services (including all parties under common control) regulated as... of the population of the PCS licensed service area for the counties contained therein, as determined... covers less than 10 percent of the population of a PCS service area if none of the base stations of the...

47 CFR 20.6 - CMRS spectrum aggregation limit.

Code of Federal Regulations, 2011 CFR

2011-10-01

... the broadband PCS, cellular, or SMR services (including all parties under common control) regulated as... of the population of the PCS licensed service area for the counties contained therein, as determined... covers less than 10 percent of the population of a PCS service area if none of the base stations of the...

76 FR 35744 - Amendments to National Emission Standards for Hazardous Air Pollutants for Area Sources: Plating...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-20

.... Regulated sources do not include chromium electroplating and chromium anodizing sources, as those sources are subject to 40 CFR part 63, subpart N, ``Chromium Emissions From Hard and Decorative Chromium Electroplating and Chromium Anodizing Tanks.'' Manufacturing 32, 33 Area source establishments engaged in one or...

33 CFR 165.767 - Security Zone; Manbirtee Key, Port of Manatee, Florida.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., Port of Manatee, Florida. 165.767 Section 165.767 Navigation and Navigable Waters COAST GUARD... § 165.767 Security Zone; Manbirtee Key, Port of Manatee, Florida. (a) Regulated area. The following area... extending 500 yards from the island's shoreline, in all directions, not to include the Port Manatee Channel...

33 CFR 165.767 - Security Zone; Manbirtee Key, Port of Manatee, Florida.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., Port of Manatee, Florida. 165.767 Section 165.767 Navigation and Navigable Waters COAST GUARD... § 165.767 Security Zone; Manbirtee Key, Port of Manatee, Florida. (a) Regulated area. The following area... extending 500 yards from the island's shoreline, in all directions, not to include the Port Manatee Channel...

33 CFR 165.767 - Security Zone; Manbirtee Key, Port of Manatee, Florida.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., Port of Manatee, Florida. 165.767 Section 165.767 Navigation and Navigable Waters COAST GUARD... § 165.767 Security Zone; Manbirtee Key, Port of Manatee, Florida. (a) Regulated area. The following area... extending 500 yards from the island's shoreline, in all directions, not to include the Port Manatee Channel...

33 CFR 165.767 - Security Zone; Manbirtee Key, Port of Manatee, Florida.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., Port of Manatee, Florida. 165.767 Section 165.767 Navigation and Navigable Waters COAST GUARD... § 165.767 Security Zone; Manbirtee Key, Port of Manatee, Florida. (a) Regulated area. The following area... extending 500 yards from the island's shoreline, in all directions, not to include the Port Manatee Channel...

33 CFR 165.827 - Regulated Navigation Area; Galveston Channel, TX.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Regulated Navigation Area... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS Specific Regulated Navigation Areas and Limited Access Areas Eighth Coast Guard District § 165.827...

33 CFR 165.827 - Regulated Navigation Area; Galveston Channel, TX.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Regulated Navigation Area... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS Specific Regulated Navigation Areas and Limited Access Areas Eighth Coast Guard District § 165.827...

7 CFR 301.86-4 - Conditions governing the interstate movement of regulated articles from quarantined areas.

Code of Federal Regulations, 2010 CFR

2010-01-01

... experimental or scientific purposes; or (ii) The regulated article originates outside the quarantined area and... regulated articles from quarantined areas. 301.86-4 Section 301.86-4 Agriculture Regulations of the... regulated articles from quarantined areas. (a) Any regulated article may be moved interstate from a...

Certification of Compliance Audit Checklist for Hazardous Waste Tanks

EPA Pesticide Factsheets

Example of a Certification of Compliance Audit Checklist -- Tanks, which includes a fillable table with areas to list requirements, federal regulations, descriptions, locations of information, and criteria met.

Biology Notes

ERIC Educational Resources Information Center

School Science Review, 1972

1972-01-01

Twelve new experiments in biology are described by teachers for use in classrooms. Broad areas covered include enzyme action, growth regulation, microscopy, respiration, germination, plant succession, leaf structure and blood structure. Explanations are detailed. (PS)

33 CFR 165.1303 - Puget Sound and adjacent waters, WA-regulated navigation area.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., WA-regulated navigation area. 165.1303 Section 165.1303 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS Specific Regulated Navigation Areas and Limited Access Areas Thirteenth Coast Guard District...

Environmental Baseline Survey, Fitzsimmons Army Medical Center, Aurora, Colorado. Volume II - Appendices A-G.

DTIC Science & Technology

1996-05-01

no hazardous substances, regulated by the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), and no petroleum products ...Guidebook, Fall 1993, are as follows: 1. Areas where no storage, release or disposal of hazardous substances orpetroleum products has occurred...including no migration of these substances from adjacent areas) [white] S2. Areas where only storage of hazardous substances or petroleum products has

Meta-analysis of real-time fMRI neurofeedback studies using individual participant data: How is brain regulation mediated?

PubMed

Emmert, Kirsten; Kopel, Rotem; Sulzer, James; Brühl, Annette B; Berman, Brian D; Linden, David E J; Horovitz, Silvina G; Breimhorst, Markus; Caria, Andrea; Frank, Sabine; Johnston, Stephen; Long, Zhiying; Paret, Christian; Robineau, Fabien; Veit, Ralf; Bartsch, Andreas; Beckmann, Christian F; Van De Ville, Dimitri; Haller, Sven

2016-01-01

An increasing number of studies using real-time fMRI neurofeedback have demonstrated that successful regulation of neural activity is possible in various brain regions. Since these studies focused on the regulated region(s), little is known about the target-independent mechanisms associated with neurofeedback-guided control of brain activation, i.e. the regulating network. While the specificity of the activation during self-regulation is an important factor, no study has effectively determined the network involved in self-regulation in general. In an effort to detect regions that are responsible for the act of brain regulation, we performed a post-hoc analysis of data involving different target regions based on studies from different research groups. We included twelve suitable studies that examined nine different target regions amounting to a total of 175 subjects and 899 neurofeedback runs. Data analysis included a standard first- (single subject, extracting main paradigm) and second-level (single subject, all runs) general linear model (GLM) analysis of all participants taking into account the individual timing. Subsequently, at the third level, a random effects model GLM included all subjects of all studies, resulting in an overall mixed effects model. Since four of the twelve studies had a reduced field of view (FoV), we repeated the same analysis in a subsample of eight studies that had a well-overlapping FoV to obtain a more global picture of self-regulation. The GLM analysis revealed that the anterior insula as well as the basal ganglia, notably the striatum, were consistently active during the regulation of brain activation across the studies. The anterior insula has been implicated in interoceptive awareness of the body and cognitive control. Basal ganglia are involved in procedural learning, visuomotor integration and other higher cognitive processes including motivation. The larger FoV analysis yielded additional activations in the anterior cingulate cortex, the dorsolateral and ventrolateral prefrontal cortex, the temporo-parietal area and the visual association areas including the temporo-occipital junction. In conclusion, we demonstrate that several key regions, such as the anterior insula and the basal ganglia, are consistently activated during self-regulation in real-time fMRI neurofeedback independent of the targeted region-of-interest. Our results imply that if the real-time fMRI neurofeedback studies target regions of this regulation network, such as the anterior insula, care should be given whether activation changes are related to successful regulation, or related to the regulation process per se. Furthermore, future research is needed to determine how activation within this regulation network is related to neurofeedback success. Copyright © 2015 Elsevier Inc. All rights reserved.

7 CFR 301.74-4 - Conditions governing the interstate movement of regulated articles from quarantined areas.

Code of Federal Regulations, 2011 CFR

2011-01-01

... regulated articles from quarantined areas. 301.74-4 Section 301.74-4 Agriculture Regulations of the... articles from quarantined areas. The interstate movement of any regulated article from a quarantined area 2... quarantines and regulations must also be met. (a) The regulated article is moved by the United States...

7 CFR 301.32-4 - Conditions governing the interstate movement of regulated articles from quarantined areas.

Code of Federal Regulations, 2011 CFR

2011-01-01

... regulated articles from quarantined areas. 301.32-4 Section 301.32-4 Agriculture Regulations of the... regulated articles from quarantined areas. Any regulated article may be moved interstate from a quarantined... permit if: (1) The regulated article originated outside the quarantined area and is either moved in an...

7 CFR 301.32-4 - Conditions governing the interstate movement of regulated articles from quarantined areas.

Code of Federal Regulations, 2010 CFR

2010-01-01

... regulated articles from quarantined areas. 301.32-4 Section 301.32-4 Agriculture Regulations of the... regulated articles from quarantined areas. Any regulated article may be moved interstate from a quarantined... permit if: (1) The regulated article originated outside the quarantined area and is either moved in an...

7 CFR 301.50-4 - Conditions governing the interstate movement of regulated articles from quarantined areas.

Code of Federal Regulations, 2010 CFR

2010-01-01

... regulated articles from quarantined areas. 301.50-4 Section 301.50-4 Agriculture Regulations of the... regulated articles from quarantined areas. Any regulated article may be moved interstate from a quarantined... certificate or limited permit, if: (1)(i) The regulated article originates outside any quarantined area and is...

7 CFR 301.74-4 - Conditions governing the interstate movement of regulated articles from quarantined areas.

Code of Federal Regulations, 2010 CFR

2010-01-01

... regulated articles from quarantined areas. 301.74-4 Section 301.74-4 Agriculture Regulations of the... articles from quarantined areas. The interstate movement of any regulated article from a quarantined area 2... quarantines and regulations must also be met. (a) The regulated article is moved by the United States...

7 CFR 301.89-5 - Movement of regulated articles from regulated areas.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Movement of regulated articles from regulated areas. 301.89-5 Section 301.89-5 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL... § 301.89-5 Movement of regulated articles from regulated areas. (a) Any regulated article may be moved...

77 FR 40547 - Special Regulations; Areas of the National Park System, Chattahoochee River National Recreation...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-10

... acres of park land, including riverside units and upland forested areas with hiking trails and other... final trail plan has 3 miles of hiking-only trails and 6.7 miles of multi-use trails allowing both... purposes. This certification is based on the cost-benefit and regulatory flexibility analysis found in the...

Case Studies on Using Strengths and Interests to Address the Needs of Students with Autism Spectrum Disorders

ERIC Educational Resources Information Center

Lanou, Aaron; Hough, Lauren; Powell, Elizabeth

2012-01-01

Students on the autism spectrum present with difficulties in a variety of areas, including social understanding, emotional regulation, academics, and behavior. Professionals working in the field of autism must identify and address these areas of need given each individual child's specific cognitive profiles. In this article the authors highlight…

75 FR 18776 - Regulated Navigation Area; Galveston Channel, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-13

... that the proposed regulated navigation area covers a small area and vessels are allowed to travel...-AA11 Regulated Navigation Area; Galveston Channel, TX AGENCY: Coast Guard, DHS. ACTION: Notice of proposed rulemaking. SUMMARY: The Coast Guard proposes to establish a regulated navigation area across the...

25 CFR 168.1 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Definitions. 168.1 Section 168.1 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GRAZING REGULATIONS FOR THE HOPI PARTITIONED LANDS AREA... including all villages and clans. (n) Allocate means to apportion grazing, including the determination of...

Final report on the waste area grouping perimeter groundwater quality monitoring well installation program at Oak Ridge National Laboratory, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

Greene, J.A.

1991-06-01

A groundwater quality monitoring well installation program was conducted at Oak Ridge National Laboratory (ORNL) to meet the requirements of environmental regulations, including the Resource Conservation and Recovery Act (RCRA) and the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA). A total of 173 wells were installed and developed at 11 different waste area groupings (WAGs) between June 1986 and November 1990. A location map of the wells is included.

7 CFR 905.13 - District.

Code of Federal Regulations, 2013 CFR

2013-01-01

... County of St. Lucie and that part of the Counties of Brevard, Indian River, Martin, and Palm Beach... Counties of Palm Beach and Martin not included in Regulation Area II. (e) Citrus District Five shall...

7 CFR 905.13 - District.

Code of Federal Regulations, 2011 CFR

2011-01-01

... County of St. Lucie and that part of the Counties of Brevard, Indian River, Martin, and Palm Beach... Counties of Palm Beach and Martin not included in Regulation Area II. (e) Citrus District Five shall...

7 CFR 905.13 - District.

Code of Federal Regulations, 2014 CFR

2014-01-01

... County of St. Lucie and that part of the Counties of Brevard, Indian River, Martin, and Palm Beach... Counties of Palm Beach and Martin not included in Regulation Area II. (e) Citrus District Five shall...

7 CFR 905.13 - District.

Code of Federal Regulations, 2012 CFR

2012-01-01

... County of St. Lucie and that part of the Counties of Brevard, Indian River, Martin, and Palm Beach... Counties of Palm Beach and Martin not included in Regulation Area II. (e) Citrus District Five shall...

Ship and Boat Building Sector (NAICS 3336)

EPA Pesticide Factsheets

Find environmental regulatory and compliance information for the shipbuilding sector (NAICS 3336), including NESHAPs and air toxics regulations, nonroad engines and vehicles, managing used oil, and polluted runoff from marinas and boating areas.

Certification of Compliance Audit Checklist for Hazardous Waste Containment Buildings

EPA Pesticide Factsheets

Example of a Certification of Compliance Audit Checklist General Information: Containment Buildings, which includes a fillable table with areas to list requirements, federal regulations, descriptions, locations of information, and criteria met.

Investigation of Academic Procrastination Prevalence and Its Relationship with Academic Self-Regulation and Achievement Motivation among High-School Students in Tehran City

ERIC Educational Resources Information Center

Ebadi, Setareh; Shakoorzadeh, Reza

2015-01-01

The present study was carried out with the aim of Investigation of academic procrastination prevalence and its relationship with academic self-regulation and achievement motivation among high-school students in Tehran city. The sample included 624 high school students (312 Boys & 312 Girls) from different areas and regions that selected using…

Endocrine, electrolyte, and fluid volume changes associated with Apollo missions

NASA Technical Reports Server (NTRS)

Leach, C. S.; Alexander, W. C.; Johnson, P. C.

1975-01-01

The endocrine and metabolic results obtained before and after the Apollo missions and the results of the limited in-flight sampling are summarized and discussed. The studies were designed to evaluate the biochemical changes in the returning Apollo crewmembers, and the areas studied included balance of fluids and electrolytes, regulation of calcium metabolism, adaptation to the environment, and regulation of metabolic processes.

7 CFR 301.52-2 - Authorization for Deputy Administrator to list regulated areas and suppressive or generally...

Code of Federal Regulations, 2013 CFR

2013-01-01

... regulated areas and suppressive or generally infested areas. 301.52-2 Section 301.52-2 Agriculture... shall list as regulated areas in a supplemental regulation designated as § 301.52-2a, the quarantined..., DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Pink Bollworm Quarantine and Regulations § 301.52-2...

7 CFR 301.52-2 - Authorization for Deputy Administrator to list regulated areas and suppressive or generally...

Code of Federal Regulations, 2012 CFR

2012-01-01

... regulated areas and suppressive or generally infested areas. 301.52-2 Section 301.52-2 Agriculture... shall list as regulated areas in a supplemental regulation designated as § 301.52-2a, the quarantined..., DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Pink Bollworm Quarantine and Regulations § 301.52-2...

7 CFR 301.52-2 - Authorization for Deputy Administrator to list regulated areas and suppressive or generally...

Code of Federal Regulations, 2011 CFR

2011-01-01

... regulated areas and suppressive or generally infested areas. 301.52-2 Section 301.52-2 Agriculture... shall list as regulated areas in a supplemental regulation designated as § 301.52-2a, the quarantined..., DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Pink Bollworm Quarantine and Regulations § 301.52-2...

7 CFR 301.52-2 - Authorization for Deputy Administrator to list regulated areas and suppressive or generally...

Code of Federal Regulations, 2010 CFR

2010-01-01

... regulated areas and suppressive or generally infested areas. 301.52-2 Section 301.52-2 Agriculture... shall list as regulated areas in a supplemental regulation designated as § 301.52-2a, the quarantined..., DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Pink Bollworm Quarantine and Regulations § 301.52-2...

7 CFR 301.52-2 - Authorization for Deputy Administrator to list regulated areas and suppressive or generally...

Code of Federal Regulations, 2014 CFR

2014-01-01

... regulated areas and suppressive or generally infested areas. 301.52-2 Section 301.52-2 Agriculture... shall list as regulated areas in a supplemental regulation designated as § 301.52-2a, the quarantined..., DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Pink Bollworm Quarantine and Regulations § 301.52-2...

7 CFR 301.75-8 - Interstate movement of regulated seed from a quarantined area.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 5 2011-01-01 2011-01-01 false Interstate movement of regulated seed from a... Citrus Canker Notice of Quarantine and Regulations § 301.75-8 Interstate movement of regulated seed from a quarantined area. Regulated seed may be moved interstate from a quarantined area into any area of...

7 CFR 301.75-8 - Interstate movement of regulated seed from a quarantined area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Interstate movement of regulated seed from a... Citrus Canker Notice of Quarantine and Regulations § 301.75-8 Interstate movement of regulated seed from a quarantined area. Regulated seed may be moved interstate from a quarantined area into any area of...

Photocatalytic Degradation of Organic Contaminants in Water

EPA Science Inventory

Photocatalytic treatment of organics, including regulated and contaminants of emerging concern, has been an important area of this field. Details are provided on the mechanism of degradation, reaction intermediates, kinetics, and nanointerfacial adsorption phenomena. The degradat...

34 CFR 648.4 - What is included in the grant?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 3 2014-07-01 2014-07-01 false What is included in the grant? 648.4 Section 648.4 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION GRADUATE ASSISTANCE IN AREAS OF NATIONAL NEED General § 648.4 What is...

34 CFR 648.4 - What is included in the grant?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 3 2011-07-01 2011-07-01 false What is included in the grant? 648.4 Section 648.4 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION GRADUATE ASSISTANCE IN AREAS OF NATIONAL NEED General § 648.4 What is...

34 CFR 648.4 - What is included in the grant?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 3 2010-07-01 2010-07-01 false What is included in the grant? 648.4 Section 648.4 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION GRADUATE ASSISTANCE IN AREAS OF NATIONAL NEED General § 648.4 What is...

34 CFR 648.4 - What is included in the grant?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 34 Education 3 2013-07-01 2013-07-01 false What is included in the grant? 648.4 Section 648.4 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION GRADUATE ASSISTANCE IN AREAS OF NATIONAL NEED General § 648.4 What is...

34 CFR 648.4 - What is included in the grant?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 34 Education 3 2012-07-01 2012-07-01 false What is included in the grant? 648.4 Section 648.4 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION GRADUATE ASSISTANCE IN AREAS OF NATIONAL NEED General § 648.4 What is...

77 FR 64076 - Vessel Traffic Service Updates, Including Establishment of Vessel Traffic Service Requirements...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-18

... Port Arthur, Texas and Expansion of VTS Special Operating Area in Puget Sound AGENCY: Coast Guard, DHS... Service (VTS) regulations in 33 CFR part 161. The proposed revisions include adding the Maritime Mobile... would impose Automatic Identification System (AIS) equipment costs for owners and operators of the...

Novel probiotics and prebiotics: road to the market.

PubMed

Kumar, Himanshu; Salminen, Seppo; Verhagen, Hans; Rowland, Ian; Heimbach, Jim; Bañares, Silvia; Young, Tony; Nomoto, Koji; Lalonde, Mélanie

2015-04-01

Novel probiotics and prebiotics designed to manipulate the gut microbiota for improving health outcomes are in demand as the importance of the gut microbiota in human health is revealed. The regulations governing introduction of novel probiotics and prebiotics vary by geographical region. Novel foods and foods with health claims fall under specific regulations in several countries. The paper reviews the main requirements of the regulations in the EU, USA, Canada and Japan. We propose a number of areas that need to be addressed in any safety assessment of novel probiotics and prebiotics. These include publication of the genomic sequence, antibiotic resistance profiling, selection of appropriate in vivo model, toxicological studies (including toxin production) and definition of target population. Copyright © 2014 Elsevier Ltd. All rights reserved.

Valve-regulated lead/acid batteries

NASA Astrophysics Data System (ADS)

Rand, D. A. J.; Holden, L. S.; May, G. J.; Newnham, R. H.; Peters, K.

Given the growing importance of valve-regulated lead/acid technology in many existing and emerging market areas, an expert panel was assembled at the Sixth Asian Battery Conference to answer questions from delegates on various technical and operational aspects of such batteries. Key issues included: advantantages; performance and reliability; thermal runaway; and failure modes. The interaction between the audience and the panel was both vigorous and informative. Overwhelmingly, it was agreed that valve-regulated technology has come of age and offers a dynamic solution to many of the world's energy-storage requirements and opportunities.

Associate Directorate Environmental Management Infrastructure Plan for Area G and Area L Domes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stevens, Patrice Ann; Baumer, Andrew Ronald

Technical Area 54, at Los Alamos National Laboratory (LANL) is situated in the east-central portion of the Laboratory on the Mesita del Buey between Pajarito Canyon to the south and Cañada del Buey to the north. TA-54 includes four MDAs designated as G, H, J, and L; a waste characterization, container storage, and transfer facility; active TRU waste and MLLW waste storage and low-level waste (LLW) disposal operations at Area G; active hazardous and mixed low-level (MLLW) waste storage operations at Area L; and administrative and support areas. MDA J has previously under-gone closure. Area G is a waste managementmore » and disposal area, used for the disposal and storage of radioactive wastes since 1957. Since August 2015, Area G has been in warm standby and provides minimal operations to support safety, compliance, and nitrate salt remediation. Located within Area G, MDA G covers 63-acres. MDA G contains 334 active and inactive waste management units, which include 36 pits, 294 shafts, and 4 trenches. In 1971, Area G began use for the retrievable storage of TRU waste. There are two pits, four trenches and 60 shafts that contain retrievable TRU waste. Thirty-three of the shafts contain TRU waste that may present unique problems for retrieval. In 1986, segregation of MLLW was initiated at Area G for treatment and temporary storage or for off-site disposal. Area G is the only active LLW disposal facility at the Laboratory. Current operations at Area G include storage and characterization of TRU and mixed TRU waste destined for off-site disposal at the Waste Isolation Pilot Plant (WIPP) in southeastern New Mexico and the storage of MLLW destined for off-site treatment and/or disposal. Several above-ground container storage units (CSUs) are currently used for storage of containerized MLLW and/or mixed TRU wastes. These consist of asphalt pads and associated fabric domes or other structures. As defined by the Consent Order, MDA G contains 229 of the 334 subsurface waste management units at Area G. These MDA G disposal units include 32 pits, 193 shafts, and 4 trenches and contain LLW, MLLW and TRU waste. The remaining 105 solid waste management units (SWMUs) include RCRA-regulated landfill and storage units and DOE-regulated LLW disposal units. The TA-54 closure project must ensure that continuing waste operations at Area G and their transition to an interim or enduring facility are coordinated with closure activities.« less

Using Self-Regulated Strategy Development for Persuasive Writing to Increase the Writing and Self-Efficacy Skills of Students with Emotional and Behavioral Disorders in Health Class

ERIC Educational Resources Information Center

Ennis, Robin Parks; Jolivette, Kristine

2014-01-01

The Common Core State Standards Initiative includes an emphasis on teaching writing and related skills in all subject areas. This study sought to improve the persuasive writing skills and self-efficacy skills of students with emotional and behavioral disorders by implementing self-regulated strategy development with pairs of students in a high…

75 FR 34320 - Asian Longhorned Beetle; Quarantined Area and Regulated Articles

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-17

.... APHIS-2010-0004] Asian Longhorned Beetle; Quarantined Area and Regulated Articles AGENCY: Animal and... of quarantined areas and restricting the interstate movement of regulated articles from that area. We are also updating the list of regulated articles in order to reflect new information concerning host...

33 CFR 165.101 - Kittery, Maine-regulated navigation area.

Code of Federal Regulations, 2011 CFR

2011-07-01

... navigation area. 165.101 Section 165.101 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS Specific Regulated Navigation Areas and Limited Access Areas First Coast Guard District § 165.101 Kittery...

33 CFR 165.101 - Kittery, Maine-regulated navigation area.

Code of Federal Regulations, 2013 CFR

2013-07-01

... navigation area. 165.101 Section 165.101 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS Specific Regulated Navigation Areas and Limited Access Areas First Coast Guard District § 165.101 Kittery...

33 CFR 165.101 - Kittery, Maine-regulated navigation area.

Code of Federal Regulations, 2012 CFR

2012-07-01

... navigation area. 165.101 Section 165.101 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS Specific Regulated Navigation Areas and Limited Access Areas First Coast Guard District § 165.101 Kittery...

33 CFR 165.101 - Kittery, Maine-regulated navigation area.

Code of Federal Regulations, 2010 CFR

2010-07-01

... navigation area. 165.101 Section 165.101 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS Specific Regulated Navigation Areas and Limited Access Areas First Coast Guard District § 165.101 Kittery...

33 CFR 165.101 - Kittery, Maine-regulated navigation area.

Code of Federal Regulations, 2014 CFR

2014-07-01

... navigation area. 165.101 Section 165.101 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS Specific Regulated Navigation Areas and Limited Access Areas First Coast Guard District § 165.101 Kittery...

Subgenual anterior cingulate cortex controls sadness-induced modulations of cognitive and emotional network hubs.

PubMed

Ramirez-Mahaluf, Juan P; Perramon, Joan; Otal, Begonya; Villoslada, Pablo; Compte, Albert

2018-06-04

The regulation of cognitive and emotional processes is critical for proper executive functions and social behavior, but its specific mechanisms remain unknown. Here, we addressed this issue by studying with functional magnetic resonance imaging the changes in network topology that underlie competitive interactions between emotional and cognitive networks in healthy participants. Our behavioral paradigm contrasted periods with high emotional and cognitive demands by including a sadness provocation task followed by a spatial working memory task. The sharp contrast between successive tasks was designed to enhance the separability of emotional and cognitive networks and reveal areas that regulate the flow of information between them (hubs). By applying graph analysis methods on functional connectivity between 20 regions of interest in 22 participants we identified two main brain network modules, one dorsal and one ventral, and their hub areas: the left dorsolateral prefrontal cortex (dlPFC) and the left medial frontal pole (mFP). These hub areas did not modulate their mutual functional connectivity following sadness but they did so through an interposed area, the subgenual anterior cingulate cortex (sACC). Our results identify dlPFC and mFP as areas regulating interactions between emotional and cognitive networks, and suggest that their modulation by sadness experience is mediated by sACC.

Immediate early gene activity in song control nuclei and brain areas regulating motivation relates positively to singing behavior during, but not outside of, a breeding context.

PubMed

Heimovics, Sarah A; Riters, Lauren V

2005-12-01

In some species, such as songbirds, much is known about how the brain regulates vocal learning, production, and perception. What remains a mystery is what regulates the motivation to communicate. European starlings (Sturnus vulgaris) sing throughout most of the year, but the social and environmental factors that motivate singing behavior differ seasonally. Male song is highly sexually motivated during, but not outside of, the breeding season. Brain areas outside the song control system, such as the medial preoptic nucleus (POM) and ventral tegmental area (VTA), have been implicated in regulating sexually motivated behaviors in birds, including song. The present study was designed to explore whether these regions, as well as three song control nuclei [area X, the high vocal center (HVC), and the robust nucleus of the arcopallium (RA)], might be involved differentially in song produced within compared to outside of a breeding context. We recorded the behavioral responses of breeding and nonbreeding condition male starlings to the introduction of a female conspecific. Males did not show context-dependent differences in the overall amount of song sung. However, immunocytochemistry for the protein product of the immediate early gene cFOS revealed a positive linear relationship between the total amount of songs sung and number of cFOS-labeled cells in POM, VTA, HVC, and RA for birds singing during, but not outside of, a breeding context. These results suggest that these regions differentially regulate male song production depending on reproductive context. Overall the data support the hypothesis that the POM and VTA interact with the song control system, specifically HVC and RA, to regulate sexually motivated vocal communication in songbirds.

New regulations for radiation protection for work involving radioactive fallout emitted by the TEPCO Fukushima Daiichi APP accident: application expansion to recovery and reconstruction work.

PubMed

Yasui, Shojiro

2014-01-01

The accident at the Fukushima Daiichi Atomic Power Plant that accompanied the Great East Japan Earthquake on March 11, 2011 released a large amount of radioactive material. To rehabilitate the contaminated areas, the government of Japan decided to carry out decontamination work. In April 2012, the Nuclear Emergency Response Headquarters (NERH) started dividing the restricted areas into three sub-areas based on the ambient dose rate. In accordance with the rearrangement of the restricted area, NERH decided to allow resumption of business activities, including manufacturing and farming, as well as operation of hospitals, welfare facilities, and shops and related subordinate tasks, such as maintenance, repair, and transportation. As a result, the government needed regulations for radiation protection for workers engaged in those activities. The issues that arose in the deliberation of the regulations were distilled into two points: 1) whether radiation protection systems established for a planned exposure situation should apply to construction and agricultural work activities in an existing exposure situation, and 2) how to simplify the regulation in accordance with the nature of the work activities. Further research and development concerning the following issues are warranted: a) the relationship between the radioactive concentrations of materials handled and the risk of internal exposure, and b) the relationship between the radioactive concentration of the soil and the surface contamination level.

78 FR 39588 - Special Local Regulations; Revision of 2013 America's Cup Regulated Area, San Francisco Bay; San...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-02

...-AA08 Special Local Regulations; Revision of 2013 America's Cup Regulated Area, San Francisco Bay; San...: The Coast Guard is revising the regulated area for the 2013 America's Cup sailing events. Previously... final rule regulating the on-water activities associated with the ``Louis Vuitton Cup,'' ``Red Bull...

33 CFR 165.767 - Security Zone; Manbirtee Key, Port of Manatee, Florida.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS Specific Regulated Navigation Areas and Limited Access Areas Seventh Coast Guard District § 165.767 Security Zone; Manbirtee Key, Port of Manatee, Florida. (a) Regulated area. The following area...

7 CFR 905.114 - Redistricting of citrus districts and reapportionment of grower members.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., Manatee, Monroe, Okeechobee, Sarasota, and that part of the counties of Palm Beach and Martin not included..., Martin, and Palm Beach described as lying within Regulation Area II, and County Commissioner's Districts...

The requirements for implementing Sustainable Development Goals (SDGs) and for planning and implementing Integrated Territorial Investments (ITI) in mining areas

NASA Astrophysics Data System (ADS)

Florkowska, Lucyna; Bryt-Nitarska, Izabela

2018-04-01

The notion of Integrated Territorial Investments (ITI) appears more and more frequently in contemporary regional development strategies. Formulating the main assumptions of ITI is a response to a growing need for a co-ordinated, multi-dimensional regional development suitable for the characteristics of a given area. Activities are mainly aimed at improving people's quality of life with their significant participation. These activities include implementing the Sustainable development Goals (SDGs). Territorial investments include, among others, projects in areas where land and building use is governed not only by general regulations (Spatial Planning and Land Development Act) but also by separate legal acts. This issue also concerns areas with active mines and post-mining areas undergoing revitalization. For the areas specified above land development and in particular making building investments is subject to the requirements set forth in the Geological and Mining Law and in the general regulations. In practice this means that factors connected with the present and future mining impacts must be taken into consideration in planning the investment process. This article discusses the role of proper assessment of local geological conditions as well as the current and future mining situation in the context of proper planning and performance of the Integrated Territorial Investment programme and also in the context of implementing the SDGs. It also describes the technical and legislative factors which need to be taken into consideration in areas where mining is planned or where it took place in the past.

77 FR 62437 - Regulated Navigation Area; Columbus Day Weekend, Biscayne Bay, Miami, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-15

...-AA11 Regulated Navigation Area; Columbus Day Weekend, Biscayne Bay, Miami, FL AGENCY: Coast Guard, DHS. ACTION: Final rule. SUMMARY: The Coast Guard is amending the Columbus Day weekend regulated navigation area on Biscayne Bay in Miami, Florida. The amended regulated navigation area alters the boundaries of...

50 CFR 648.91 - Monkfish regulated mesh areas and restrictions on gear and methods of fishing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... while on a monkfish DAS. Except as provided in paragraph (c)(1)(ii) of this section, the minimum mesh size for any trawl net, including beam trawl nets, used by a vessel fishing under a monkfish DAS is 10... area being fished. (ii) Trawl nets while on a monkfish and NE multispecies DAS. Vessels issued a...

Leadership Handbook for the Armor Officer. Volume 2. Headaches, Heartbeats, and Hamstrings: A Guide to Company Level Duties and Functions

DTIC Science & Technology

1986-01-01

should be formalized in the area of responsibilities held by any officer. This volume provides guidelines for many of the situations that are common...but are not directive and local SOPs’ should be followed in accordance with Army and Command regulations. Protocol, Etiquette and Service Customs are...listed for many of the areas of Army Life that should help to avoid possible problem areas. Coverage includes Checklists, Additional Duties and other

7 CFR 301.85-2a - Regulated areas; suppressive and generally infested areas.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Nematode Quarantine and Regulations § 301.85-2a Regulated areas; suppressive and generally infested areas. The civil divisions and parts of civil divisions described below are designated as golden nematode...

7 CFR 301.85-2a - Regulated areas; suppressive and generally infested areas.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Nematode Quarantine and Regulations § 301.85-2a Regulated areas; suppressive and generally infested areas. The civil divisions and parts of civil divisions described below are designated as golden nematode...

7 CFR 301.85-2a - Regulated areas; suppressive and generally infested areas.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Nematode Quarantine and Regulations § 301.85-2a Regulated areas; suppressive and generally infested areas. The civil divisions and parts of civil divisions described below are designated as golden nematode...

7 CFR 301.85-2a - Regulated areas; suppressive and generally infested areas.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Nematode Quarantine and Regulations § 301.85-2a Regulated areas; suppressive and generally infested areas. The civil divisions and parts of civil divisions described below are designated as golden nematode...

78 FR 27856 - Golden Nematode; Removal of Regulated Areas in Livingston and Steuben Counties, NY

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-13

.... APHIS-2012-0079] Golden Nematode; Removal of Regulated Areas in Livingston and Steuben Counties, NY... nematode regulations by removing areas in Livingston and Steuben Counties in New York from the list of... nematode, and we determined that regulation of these areas was no longer necessary. As a result of that...

7 CFR 301.51-4 - Conditions governing the interstate movement of regulated articles from quarantined areas.

Code of Federal Regulations, 2014 CFR

2014-01-01

... regulated articles from quarantined areas. 301.51-4 Section 301.51-4 Agriculture Regulations of the... DOMESTIC QUARANTINE NOTICES Asian Longhorned Beetle § 301.51-4 Conditions governing the interstate movement of regulated articles from quarantined areas. (a) Any regulated article may be moved interstate from...

7 CFR 301.51-4 - Conditions governing the interstate movement of regulated articles from quarantined areas.

Code of Federal Regulations, 2012 CFR

2012-01-01

... regulated articles from quarantined areas. 301.51-4 Section 301.51-4 Agriculture Regulations of the... DOMESTIC QUARANTINE NOTICES Asian Longhorned Beetle § 301.51-4 Conditions governing the interstate movement of regulated articles from quarantined areas. (a) Any regulated article may be moved interstate from...

7 CFR 301.51-4 - Conditions governing the interstate movement of regulated articles from quarantined areas.

Code of Federal Regulations, 2011 CFR

2011-01-01

... regulated articles from quarantined areas. 301.51-4 Section 301.51-4 Agriculture Regulations of the... DOMESTIC QUARANTINE NOTICES Asian Longhorned Beetle § 301.51-4 Conditions governing the interstate movement of regulated articles from quarantined areas. (a) Any regulated article may be moved interstate from...

28 CFR 35.190 - Designated agencies.

Code of Federal Regulations, 2013 CFR

2013-07-01

... responsibilities, regulate, or administer services, programs, or activities in the following functional areas. (1... institutions, institutions of higher education and vocational education (other than schools of medicine... social services, including schools of medicine, dentistry, nursing, and other health-related schools, the...

28 CFR 35.190 - Designated agencies.

Code of Federal Regulations, 2014 CFR

2014-07-01

... responsibilities, regulate, or administer services, programs, or activities in the following functional areas. (1... institutions, institutions of higher education and vocational education (other than schools of medicine... social services, including schools of medicine, dentistry, nursing, and other health-related schools, the...

28 CFR 35.190 - Designated agencies.

Code of Federal Regulations, 2012 CFR

2012-07-01

... responsibilities, regulate, or administer services, programs, or activities in the following functional areas. (1... institutions, institutions of higher education and vocational education (other than schools of medicine... social services, including schools of medicine, dentistry, nursing, and other health-related schools, the...

Ecosystem Services Assessment of the Nemunas River Delta

EPA Science Inventory

The concept of ecosystem services recognizes the services, and benefits, provided to people by ecosystems. The Nemunas River Delta, in Lithuania, provides many ecosystem services to the people of the area, including food, fuel, transportation, climate regulation, water purificati...

75 FR 67214 - Special Local Regulations for Marine Events; Wrightsville Channel, Wrightsville Beach, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-02

... side activities in the event area. The category of water activities includes but is not limited to sail boat regattas, boat parades, power boat racing, swimming events, crew racing, and sail board racing...

Neural Correlates of Automatic Mood Regulation in Girls at High Risk for Depression

PubMed Central

Joormann, Jutta; Cooney, Rebecca E.; Henry, Melissa L.; Gotlib, Ian H.

2012-01-01

Daughters of depressed mothers are at significantly elevated risk for developing a depressive disorder themselves. We have little understanding, however, of the specific factors that contribute to this risk. The ability to regulate negative affect effectively is critical to emotional and physical health and may play an important role in influencing risk for depression. We examined whether never-disordered daughters whose mothers have experienced recurrent episodes of depression during their daughters’ lifetime differ from never-disordered daughters of never-disordered mothers in their patterns of neural activation during a negative mood induction and during automatic mood regulation. Sad mood was induced in daughters through the use of film clips; daughters then recalled positive autobiographical memories, a procedure shown previously to repair negative affect. During the mood induction, high-risk girls exhibited greater activation than did low-risk daughters in brain areas that have frequently been implicated in the experience of negative affect, including the amygdala and ventrolateral prefrontal cortex. In contrast, during automatic mood regulation, low-risk daughters exhibited greater activation than did their high-risk counterparts in brain areas that have frequently been associated with top-down regulation of emotion, including the dorsolateral prefrontal cortex and dorsal anterior cingulate cortex. These findings indicate that girls at high and low risk for depression differ in their patterns of neural activation both while experiencing, and while repairing negative affect, and suggest that anomalies in neural functioning precede the onset of a depressive episode. PMID:21895344

Synthetic biology: navigating the challenges ahead.

PubMed

Bhutkar, Arjun

2005-01-01

The emerging field of synthetic biology is broadly defined as the area of intersection of biology and engineering that focuses on the modification or creation of novel biological systems that do not have a counterpart in nature. Potential applications of this technology range from creating systems for environmental cleanup tasks, for medical diagnosis and treatment, to economical generation of hydrogen fuel. This technology is in tis nascent state and there are a number of concerns surrounding its potential applications and the nature of research being performed. With the potential to create hitherto unknown "living organisms", it raises a number of challenges along different dimensions. This article reviews the current state of the technology and analyzes synthetic biology using different lenses: patentability, ethics, and regulation. It proposes a classification system for the products of synthetic biology and provides recommendations in each of the above areas (patentability, ethics, and regulation) in the context of this classification system. These recommendations include an improved framework for patentability testing, ethical principles to guide work in this area, a controlled approval process, and reference frameworks for regulation.

33 CFR 165.709 - Security Zone; Charleston Harbor, Cooper River, South Carolina.

Code of Federal Regulations, 2010 CFR

2010-07-01

... desiring to transit the Regulated Area may contact the Captain of the Port via VHF-FM channel 16 or by..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS Specific Regulated Navigation Areas and Limited Access Areas Seventh Coast Guard District...

33 CFR 165.1122 - San Diego Bay, Mission Bay and their Approaches-Regulated navigation area.

Code of Federal Regulations, 2011 CFR

2011-07-01

... area. (a) Regulated navigation area. The following area is a regulated navigation area (RNA): All... coordinates reference 1983 North American Datum (NAD 83). (b) Definitions. As used in this section— COLREGS... means every description of watercraft or other artificial contrivance used, or capable of being used, as...

33 CFR 165.1122 - San Diego Bay, Mission Bay and their Approaches-Regulated navigation area.

Code of Federal Regulations, 2013 CFR

2013-07-01

... area. (a) Regulated navigation area. The following area is a regulated navigation area (RNA): All... coordinates reference 1983 North American Datum (NAD 83). (b) Definitions. As used in this section— COLREGS... means every description of watercraft or other artificial contrivance used, or capable of being used, as...

33 CFR 165.1122 - San Diego Bay, Mission Bay and their Approaches-Regulated navigation area.

Code of Federal Regulations, 2010 CFR

2010-07-01

... area. (a) Regulated navigation area. The following area is a regulated navigation area (RNA): All... coordinates reference 1983 North American Datum (NAD 83). (b) Definitions. As used in this section— COLREGS... means every description of watercraft or other artificial contrivance used, or capable of being used, as...

33 CFR 165.1122 - San Diego Bay, Mission Bay and their Approaches-Regulated navigation area.

Code of Federal Regulations, 2012 CFR

2012-07-01

... area. (a) Regulated navigation area. The following area is a regulated navigation area (RNA): All... coordinates reference 1983 North American Datum (NAD 83). (b) Definitions. As used in this section— COLREGS... means every description of watercraft or other artificial contrivance used, or capable of being used, as...

33 CFR 165.1122 - San Diego Bay, Mission Bay and their Approaches-Regulated navigation area.

Code of Federal Regulations, 2014 CFR

2014-07-01

... area. (a) Regulated navigation area. The following area is a regulated navigation area (RNA): All... coordinates reference 1983 North American Datum (NAD 83). (b) Definitions. As used in this section— COLREGS... means every description of watercraft or other artificial contrivance used, or capable of being used, as...

7 CFR 966.4 - Production area and regulated area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Production area and regulated area. 966.4 Section 966.4 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE TOMATOES...

7 CFR 1942.306 - Purposes of grants.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS... emerging private business enterprises in rural areas including, but not limited to, the following: (1... and charges for professional services necessary for the planning and development of the project...

Common Rule Revisions: The Saga Continues

EPA Science Inventory

The Common Rule regulations that govern human subjects research were revised in 2017, after a 6-year rulemaking process. Changes were made in many areas, including informed consent, continuing review, exemptions and multi-site research, with an effective date of January 2018 (cur...

76 FR 27890 - Special Local Regulations for Marine Events; Severn River, Spa Creek and Annapolis Harbor...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-13

... area. The category of water activities includes but is not limited to sail boat regattas, boat parades, power boat racing, swimming events, crew racing, canoe and sail board racing. An environmental analysis...

77 FR 15602 - Special Local Regulations for Marine Events; Spa Creek and Annapolis Harbor, Annapolis, MD

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-16

... side activities in the event area. The category of water activities includes but is not limited to sail boat regattas, boat parades, power boat racing, swimming events, crew racing, canoe and sail board...

76 FR 55556 - Special Local Regulation for Marine Events; Chesapeake Bay Workboat Race; Back River, Messick...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-08

... side activities in the event area. The category of water activities includes but is not limited to sail boat regattas, boat parades, power boat racing, swimming events, crew racing, and sail board racing...

The role of activated charcoal in plant tissue culture.

PubMed

Thomas, T Dennis

2008-01-01

Activated charcoal has a very fine network of pores with large inner surface area on which many substances can be adsorbed. Activated charcoal is often used in tissue culture to improve cell growth and development. It plays a critical role in micropropagation, orchid seed germination, somatic embryogenesis, anther culture, synthetic seed production, protoplast culture, rooting, stem elongation, bulb formation etc. The promotary effects of AC on morphogenesis may be mainly due to its irreversible adsorption of inhibitory compounds in the culture medium and substancially decreasing the toxic metabolites, phenolic exudation and brown exudate accumulation. In addition to this activated charcoal is involved in a number of stimulatory and inhibitory activities including the release of substances naturally present in AC which promote growth, alteration and darkening of culture media, and adsorption of vitamins, metal ions and plant growth regulators, including abscisic acid and gaseous ethylene. The effect of AC on growth regulator uptake is still unclear but some workers believe that AC may gradually release certain adsorbed products, such as nutrients and growth regulators which become available to plants. This review focuses on the various roles of activated charcoal in plant tissue culture and the recent developments in this area.

Controlling Methane Emissions in the Natural Gas Sector. A Review of Federal and State Regulatory Frameworks Governing Production, Gathering, Processing, Transmission, and Distribution

DOE Office of Scientific and Technical Information (OSTI.GOV)

Paranhos, Elizabeth; Kozak, Tracy G.; Boyd, William

This report provides an overview of the regulatory frameworks governing natural gas supply chain infrastructure siting, construction, operation, and maintenance. Information was drawn from a number of sources, including published analyses, government reports, in addition to relevant statutes, court decisions and regulatory language, as needed. The scope includes all onshore facilities that contribute to methane emissions from the natural gas sector, focusing on three areas of state and federal regulations: (1) natural gas pipeline infrastructure siting and transportation service (including gathering, transmission, and distribution pipelines), (2) natural gas pipeline safety, and (3) air emissions associated with the natural gas supplymore » chain. In addition, the report identifies the incentives under current regulatory frameworks to invest in measures to reduce leakage, as well as the barriers facing investment in infrastructure improvement to reduce leakage. Policy recommendations regarding how federal or state authorities could regulate methane emissions are not provided; rather, existing frameworks are identified and some of the options for modifying existing regulations or adopting new regulations to reduce methane leakage are discussed.« less

75 FR 81832 - Asian Longhorned Beetle; Quarantined Area and Regulated Articles

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-29

.... APHIS-2010-0004] Asian Longhorned Beetle; Quarantined Area and Regulated Articles AGENCY: Animal and... interstate movement of regulated articles from that area. The interim rule also updated the list of regulated articles in order to reflect new information concerning host plants. The interim rule was necessary to...

76 FR 52541 - Asian Longhorned Beetle; Quarantined Areas and Regulated Articles

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-23

.... APHIS-2010-0128] Asian Longhorned Beetle; Quarantined Areas and Regulated Articles AGENCY: Animal and... interstate movement of regulated articles from those areas will be restricted. We are also updating the list of regulated articles in order to reflect new information concerning host plants. These actions are...

EPA's Implementation of Laws Regulating Asbestos Hazards in Schools and in the Air. Hearing before a Subcommittee of the Committee on Government Operations. House of Representatives, One Hundredth Congress, Second Session.

ERIC Educational Resources Information Center

Congress of the U. S., Washington, DC. House Committee on Government Operations.

A hearing was held by the Subcommittee on Environment, Energy, and Natural Resources on the Environmental Protection Agency's (EPA) implementation of laws regulating asbestos hazards in schools and in the air. Presented are testimony as well as letters and statements submitted for the record by leading authorities in the area including: (1) James…

Space shuttle OMS helium regulator design and development

NASA Technical Reports Server (NTRS)

Wichmann, H.; Kelly, T. L.; Lynch, R.

1974-01-01

Analysis, design, fabrication and design verification testing was conducted on the technological feasiblity of the helium pressurization regulator for the space shuttle orbital maneuvering system application. A prototype regulator was fabricated which was a single-stage design featuring the most reliable and lowest cost concept. A tradeoff study on regulator concepts indicated that a single-stage regulator with a lever arm between the valve and the actuator section would offer significant weight savings. Damping concepts were tested to determine the amount of damping required to restrict actuator travel during vibration. Component design parameters such as spring rates, effective area, contamination cutting, and damping were determined by test prior to regulator final assembly. The unit was subjected to performance testing at widely ranging flow rates, temperatures, inlet pressures, and random vibration levels. A test plan for propellant compatibility and extended life tests is included.

[Urban ecosystem services: A review].

PubMed

Mao, Qi-zheng; Huang, Gan-lin; Wu, Jian-guo

2015-04-01

Maintaining and improving ecosystem services in urban areas and human well-being are essential for sustainable development and therefore constitute an important topic in urban ecology. Here we reviewed studies on ecosystem services in urban areas. Based on the concept and classification of urban ecosystem services, we summarized characteristics of urban ecosystem services, including the human domination, high demand of ecosystem services in urban areas, spatial heterogeneity and temporal dynamics of ecosystem services supply and demand in urban areas, multi-services of urban green infrastructures, the socio-economic dimension of ecosystem services supply and ecosystem disservices in urban areas. Among different urban ecosystem services, the regulating service and cultural service are particularly indispensable to benefit human health. We pointed out that tradeoffs among different types of ecosystem services mostly occur between supportive service and cultural service, as well as regulating service and cultural service. In particular, we emphasized the relationship between landscape design (i.e. green infrastructure) and ecosystem services supply. Finally, we discussed current gaps to link urban ecosystem services studies to landscape design and management and pointed out several directions for future research in urban ecosystem services.

10 CFR 850.26 - Regulated areas.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Regulated areas. 850.26 Section 850.26 Energy DEPARTMENT OF ENERGY CHRONIC BERYLLIUM DISEASE PREVENTION PROGRAM Specific Program Requirements § 850.26 Regulated areas. (a) If airborne concentrations of beryllium in areas in DOE facilities are measured at or...

Hypoxia regulates macrophage functions in inflammation.

PubMed

Murdoch, Craig; Muthana, Munitta; Lewis, Claire E

2005-11-15

The presence of areas of hypoxia is a prominent feature of various inflamed, diseased tissues, including malignant tumors, atherosclerotic plaques, myocardial infarcts, the synovia of joints with rheumatoid arthritis, healing wounds, and sites of bacterial infection. These areas form when the blood supply is occluded and/or unable to keep pace with the growth and/or infiltration of inflammatory cells in a given area. Macrophages are present in all tissues of the body where they normally assist in guarding against invading pathogens and regulate normal cell turnover and tissue remodeling. However, they are also known to accumulate in large numbers in such ischemic/hypoxic sites. Recent studies show that macrophages then respond rapidly to the hypoxia present by altering their expression of a wide array of genes. In the present study, we outline and compare the phenotypic responses of macrophages to hypoxia in different diseased states and the implications of these for their progression and treatment.

Fats and oils: An overview

USDA-ARS?s Scientific Manuscript database

Dietary fat is a macronutrient that has historically engendered considerable controversy and continues to do so. Contentious areas include optimal amount and type for cardiovascular disease risk reduction, and role in body weight regulation. Dietary fats and oils are unique in modern times in that ...

29 CFR 1910.1001 - Asbestos.

Code of Federal Regulations, 2014 CFR

2014-07-01

... regulated areas. Building/facility owner is the legal entity, including a lessee, which exercises control... education, training, and experience to anticipate, recognize, evaluate and develop controls for occupational... appendix A to this section, or by an equivalent method. (2) Excursion limit. The employer shall ensure that...

29 CFR 1910.1001 - Asbestos.

Code of Federal Regulations, 2012 CFR

2012-07-01

... regulated areas. Building/facility owner is the legal entity, including a lessee, which exercises control... education, training, and experience to anticipate, recognize, evaluate and develop controls for occupational... appendix A to this section, or by an equivalent method. (2) Excursion limit. The employer shall ensure that...

Collection Development in a Maritime College Library

ERIC Educational Resources Information Center

Fitzpatrick, Jane Brodsky

2004-01-01

Collection development in the highly specialized area of the United States merchant marine, which includes navigation, marine engineering, shipping, naval architecture and shipbuilding, and seamanship, requires familiarity with the national and international organizations, governmental and other, which regulate and oversee the marine industry.…

45 CFR 1616.3 - Qualifications.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 4 2012-10-01 2012-10-01 false Qualifications. 1616.3 Section 1616.3 Public Welfare Regulations Relating to Public Welfare (Continued) LEGAL SERVICES CORPORATION ATTORNEY HIRING..., including, in areas where significant numbers of eligible clients speak a language other than English as...

45 CFR 1616.3 - Qualifications.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 4 2014-10-01 2014-10-01 false Qualifications. 1616.3 Section 1616.3 Public Welfare Regulations Relating to Public Welfare (Continued) LEGAL SERVICES CORPORATION ATTORNEY HIRING..., including, in areas where significant numbers of eligible clients speak a language other than English as...

45 CFR 1616.3 - Qualifications.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 4 2013-10-01 2013-10-01 false Qualifications. 1616.3 Section 1616.3 Public Welfare Regulations Relating to Public Welfare (Continued) LEGAL SERVICES CORPORATION ATTORNEY HIRING..., including, in areas where significant numbers of eligible clients speak a language other than English as...

30 CFR 282.12 - Director's responsibilities.

Code of Federal Regulations, 2010 CFR

2010-07-01

... completion of an environmental assessment or other NEPA document prepared pursuant to the regulations... are conducted in a manner that protects the environment and promotes orderly development of OCS..., any natural resource (including OCS mineral deposits and oil, gas, and sulphur resources in areas...

45 CFR 1616.3 - Qualifications.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 4 2011-10-01 2011-10-01 false Qualifications. 1616.3 Section 1616.3 Public Welfare Regulations Relating to Public Welfare (Continued) LEGAL SERVICES CORPORATION ATTORNEY HIRING..., including, in areas where significant numbers of eligible clients speak a language other than English as...

7 CFR 3405.2 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., education, or technology to give expert advice on the merit of grant applications in such fields, who... Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE RESEARCH, EDUCATION, AND EXTENSION... least one discipline or area of the food and agricultural sciences. The definition includes a research...

Slope, Scarp and Sea Cliff Instability Susceptibility Mapping for Planning Regulations in Almada County, Portugal

NASA Astrophysics Data System (ADS)

Marques, Fernando; Queiroz, Sónia; Gouveia, Luís; Vasconcelos, Manuel

2017-12-01

In Portugal, the modifications introduced in 2008 and 2012 in the National Ecological Reserve law (REN) included the mandatory study of slope instability, including slopes, natural scarps, and sea cliffs, at municipal or regional scale, with the purpose of avoiding the use of hazardous zones with buildings and other structures. The law also indicates specific methods to perform these studies, with different approaches for slope instability, natural scarps and sea cliffs. The methods used to produce the maps required by REN law, with modifications and improvements to the law specified methods, were applied to the 71 km2 territory of Almada County, and included: 1) Slope instability mapping using the statistically based Information Value method validated with the landslide inventory using ROC curves, which provided an AAC=0.964, with the higher susceptibility zones which cover at least 80% of the landslides of the inventory to be included in REN map. The map was object of a generalization process to overcome the inconveniences of the use of a pixel based approach. 2) Natural scarp mapping including setback areas near the top, defined according to the law and setback areas near the toe defined by the application of the shadow angle calibrated with the major rockfalls which occurred in the study area; 3) Sea cliffs mapping including two levels of setback zones near the top, and one setback zone at the cliffs toe, which were based on systematic inventories of cliff failures occurred between 1947 and 2010 in a large scale regional littoral monitoring project. In the paper are described the methods used and the results obtained in this study, which correspond to the final maps of areas to include in REN. The results obtained in this study may be considered as an example of good practice of the municipal authorities in terms of solid, technical and scientifically supported regulation definitions, hazard prevention and safe and sustainable land use management.

Using the SCERTS model assessment tool to identify music therapy goals for clients with autism spectrum disorder.

PubMed

Walworth, Darcy D; Register, Dena; Engel, Judy Nguyen

2009-01-01

The purposes of this paper were to identify and compare goals and objectives addressed by music therapists that are contained in the SCERTS Model, for use with children at risk or diagnosed with a communication impartment including Autism Spectrum Disorder (ASD). A video analysis of music therapists working with clients at risk or diagnosed with ASD (N = 33) was conducted to: (a) identify the areas of the SCERTS assessment model that music therapists are currently addressing within their sessions for clients with ASD, and (b) compare the frequency of SCERTS domains and goals addressed by music therapists within sessions. Results of the analysis revealed that all three domains of social communication, emotional regulation, and transactional support were addressed within music therapy sessions. Within each domain both broad goals were all addressed including joint attention and symbol use for social communication, self-regulation and mutual regulation for emotional regulation, and interpersonal support and learning support for transactional support. Overall, music therapists addressed transactional support goals and subgoals more often than social communication and emotional regulation goals and subgoals. The highest frequency goal area addressed was interpersonal support (73.96%) and the lowest goal area addressed was joint attention (35.96%). For the social partner and language partner language stages, 58 of the 320 possible subgoals were addressed with 90% frequency or higher, while 13 of the same subgoals were never addressed. The SCERTS Model is designed for use by a multidisciplinary team of professionals and family members throughout a client's treatment and contains an ongoing assessment tool with resulting goals and objectives. This analysis indicates that many SCERTS goals and objectives can be addressed in music therapy interventions. Additionally, goals and subgoals not previously recognized in music therapy treatment can be generated by the use of the SCERTS Model.

Associations Between Emotion Regulation and Social Impairment in Children and Adolescents with Autism Spectrum Disorder.

PubMed

Goldsmith, Samantha F; Kelley, Elizabeth

2018-06-01

In typically-developing (TD) individuals, effective emotion regulation strategies have been associated with positive outcomes in various areas, including social functioning. Although impaired social functioning is a core criterion of Autism Spectrum Disorder (ASD), the role of emotion regulation ability in ASD has been largely ignored. This study investigated the association between emotion regulation and ASD symptomatology, with a specific emphasis on social impairment. We used parent-report questionnaires to assess the regulatory strategies and symptom severity of 145 youth with ASD. Results showed that: (1) more effective emotion regulation, defined by greater use of reappraisal, predicted less severe ASD symptomatology, and (2) greater use of reappraisal predicted less severe social impairment. Suppression was not predictive of general symptomatology or social functioning.

33 CFR 165.714 - Regulated Navigation Area; Atlantic Ocean, Charleston, SC.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Regulated Navigation Area; Atlantic Ocean, Charleston, SC. 165.714 Section 165.714 Navigation and Navigable Waters COAST GUARD... § 165.714 Regulated Navigation Area; Atlantic Ocean, Charleston, SC. (a) Location. The following area is...

33 CFR 165.714 - Regulated Navigation Area; Atlantic Ocean, Charleston, SC.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Regulated Navigation Area; Atlantic Ocean, Charleston, SC. 165.714 Section 165.714 Navigation and Navigable Waters COAST GUARD... § 165.714 Regulated Navigation Area; Atlantic Ocean, Charleston, SC. (a) Location. The following area is...

33 CFR 165.714 - Regulated Navigation Area; Atlantic Ocean, Charleston, SC.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Regulated Navigation Area; Atlantic Ocean, Charleston, SC. 165.714 Section 165.714 Navigation and Navigable Waters COAST GUARD... § 165.714 Regulated Navigation Area; Atlantic Ocean, Charleston, SC. (a) Location. The following area is...

33 CFR 165.714 - Regulated Navigation Area; Atlantic Ocean, Charleston, SC.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Regulated Navigation Area; Atlantic Ocean, Charleston, SC. 165.714 Section 165.714 Navigation and Navigable Waters COAST GUARD... § 165.714 Regulated Navigation Area; Atlantic Ocean, Charleston, SC. (a) Location. The following area is...

33 CFR 165.714 - Regulated Navigation Area; Atlantic Ocean, Charleston, SC.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Regulated Navigation Area; Atlantic Ocean, Charleston, SC. 165.714 Section 165.714 Navigation and Navigable Waters COAST GUARD... § 165.714 Regulated Navigation Area; Atlantic Ocean, Charleston, SC. (a) Location. The following area is...

7 CFR 301.45-4 - Conditions governing the interstate movement of regulated articles and outdoor household articles...

Code of Federal Regulations, 2012 CFR

2012-01-01

... regulated articles and outdoor household articles from generally infested areas. 301.45-4 Section 301.45-4... the interstate movement of regulated articles and outdoor household articles from generally infested areas. (a) Regulated articles and outdoor household articles from generally infested areas. (1) A...

7 CFR 301.45-4 - Conditions governing the interstate movement of regulated articles and outdoor household articles...

Code of Federal Regulations, 2013 CFR

2013-01-01

... regulated articles and outdoor household articles from generally infested areas. 301.45-4 Section 301.45-4... the interstate movement of regulated articles and outdoor household articles from generally infested areas. (a) Regulated articles and outdoor household articles from generally infested areas. (1) A...

7 CFR 301.45-4 - Conditions governing the interstate movement of regulated articles and outdoor household articles...

Code of Federal Regulations, 2014 CFR

2014-01-01

... regulated articles and outdoor household articles from generally infested areas. 301.45-4 Section 301.45-4... the interstate movement of regulated articles and outdoor household articles from generally infested areas. (a) Regulated articles and outdoor household articles from generally infested areas. (1) A...

7 CFR 301.45-4 - Conditions governing the interstate movement of regulated articles and outdoor household articles...

Code of Federal Regulations, 2011 CFR

2011-01-01

... regulated articles and outdoor household articles from generally infested areas. 301.45-4 Section 301.45-4... the interstate movement of regulated articles and outdoor household articles from generally infested areas. (a) Regulated articles and outdoor household articles from generally infested areas. (1) A...

7 CFR 301.38-4 - Interstate movement of regulated articles.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 5 2012-01-01 2012-01-01 false Interstate movement of regulated articles. 301.38-4...-4 Interstate movement of regulated articles. (a) Non-protected areas. Interstate movement of regulated articles into or through any State or area that is not designated as a protected area under § 301...

7 CFR 301.38-4 - Interstate movement of regulated articles.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 5 2011-01-01 2011-01-01 false Interstate movement of regulated articles. 301.38-4...-4 Interstate movement of regulated articles. (a) Non-protected areas. Interstate movement of regulated articles into or through any State or area that is not designated as a protected area under § 301...

7 CFR 301.92-3 - Quarantined and regulated areas.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 5 2013-01-01 2013-01-01 false Quarantined and regulated areas. 301.92-3 Section 301.92-3 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Phytophthora Ramorum § 301.92-3 Quarantined and regulated areas. (a)...

7 CFR 301.92-3 - Quarantined and regulated areas.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Quarantined and regulated areas. 301.92-3 Section 301.92-3 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Phytophthora Ramorum § 301.92-3 Quarantined and regulated areas. (a)...

7 CFR 301.92-3 - Quarantined and regulated areas.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 5 2014-01-01 2014-01-01 false Quarantined and regulated areas. 301.92-3 Section 301.92-3 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Phytophthora Ramorum § 301.92-3 Quarantined and regulated areas. (a)...

7 CFR 301.92-3 - Quarantined and regulated areas.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 5 2011-01-01 2011-01-01 false Quarantined and regulated areas. 301.92-3 Section 301.92-3 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Phytophthora Ramorum § 301.92-3 Quarantined and regulated areas. (a)...

7 CFR 301.92-3 - Quarantined and regulated areas.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 5 2012-01-01 2012-01-01 false Quarantined and regulated areas. 301.92-3 Section 301.92-3 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Phytophthora Ramorum § 301.92-3 Quarantined and regulated areas. (a)...

25 CFR 249.2 - Area regulations.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Area regulations. 249.2 Section 249.2 Indians BUREAU OF... Provisions § 249.2 Area regulations. (a) The Secretary of the Interior may upon request of an Indian tribe, request of a State Governor, or upon his own motion, and upon finding that Federal regulation of Indian...

25 CFR 249.2 - Area regulations.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 1 2011-04-01 2011-04-01 false Area regulations. 249.2 Section 249.2 Indians BUREAU OF... Provisions § 249.2 Area regulations. (a) The Secretary of the Interior may upon request of an Indian tribe, request of a State Governor, or upon his own motion, and upon finding that Federal regulation of Indian...

32 CFR 552.25 - Entry regulations for certain Army training areas in Hawaii.

Code of Federal Regulations, 2010 CFR

2010-07-01

... in Hawaii. 552.25 Section 552.25 National Defense Department of Defense (Continued) DEPARTMENT OF THE... Regulations for Certain Army Training Areas in Hawaii § 552.25 Entry regulations for certain Army training areas in Hawaii. (a) Purpose. (1) This regulation establishes procedures governing the entry onto...

Comprehensive Lifecycle Planning and Management System For Addressing Water Issues Associated With Shale Gas Development In New York, Pennsylvania, And West Virginia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Arthur, J. Daniel

2012-07-01

The objective of this project is to develop a modeling system to allow operators and regulators to plan all aspects of water management activities associated with shale gas development in the target project area of New York, Pennsylvania, and West Virginia (target area ), including water supply, transport, storage, use, recycling, and disposal and which can be used for planning, managing, forecasting, permit tracking, and compliance monitoring. The proposed project is a breakthrough approach to represent the entire shale gas water lifecycle in one comprehensive system with the capability to analyze impacts and options for operational efficiency and regulatory trackingmore » and compliance, and to plan for future water use and disposition. It will address all of the major water-related issues of concern associated with shale gas development in the target area, including water withdrawal, transport, storage, use, treatment, recycling, and disposal. It will analyze the costs, water use, and wastes associated with the available options, and incorporate constraints presented by permit requirements, agreements, local and state regulations, equipment and material availability, etc. By using the system to examine the water lifecycle from withdrawals through disposal, users will be able to perform scenario analysis to answer "what if" questions for various situations. The system will include regulatory requirements of the appropriate state and regional agencies and facilitate reporting and permit applications and tracking. These features will allow operators to plan for more cost effective resource production. Regulators will be able to analyze impacts of development over an entire area. Regulators can then make informed decisions about the protections and practices that should be required as development proceeds. This modeling system will have myriad benefits for industry, government, and the public. For industry, it will allow planning all water management operations for a project or an area as one entity to optimize water use and minimize costs subject to regulatory and other constraints. It will facilitate analysis of options and tradeoffs, and will also simplify permitting and reporting to regulatory agencies. The system will help regulators study cumulative impacts of development, conserve water resources, and manage disposal options across a region. It will also allow them to track permits and monitor compliance. The public will benefit from water conservation, improved environmental performance as better system wide decisions are made, and greater supply of natural gas, with attendant lower prices, as costs are reduced and development is assisted through better planning and scheduling. Altogether, better economics and fewer barriers will facilitate recovery of the more than 300 trillion cubic feet of estimated recoverable natural gas resource in the Marcellus Shale in a manner that protects the environment.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grogin, Phillip W.

A powered industrial truck (PIT) is defined as a mobile, powerdriven vehicle used to carry, push, pull, lift, or stack material (not including vehicles intended primarily for earth moving). There are many types of and names for PITs, including forklifts, trucks, fork trucks, platform lift trucks, motorized hand trucks, and tractors. Although not every PIT is a forklift, because PITs are commonly called “forklifts,” this course manual generally uses the term “forklift,” although at times the terms “truck” and “PIT” are also used. In some areas of this course, you will see green boxes that refer to the Occupational Safetymore » and Health Administration (OSHA) regulation for PITs, which is 29 Code of Federal Regulations (CFR) 1910.178, Powered Industrial Trucks. The letter in the parentheses refers to the specific section of the regulation.« less

Reward, addiction, and emotion regulation systems associated with rejection in love.

PubMed

Fisher, Helen E; Brown, Lucy L; Aron, Arthur; Strong, Greg; Mashek, Debra

2010-07-01

Romantic rejection causes a profound sense of loss and negative affect. It can induce clinical depression and in extreme cases lead to suicide and/or homicide. To begin to identify the neural systems associated with this natural loss state, we used functional magnetic resonance imaging to study 10 women and 5 men who had recently been rejected by a partner but reported they were still intensely "in love." Participants alternately viewed a photograph of their rejecting beloved and a photograph of a familiar, individual, interspersed with a distraction-attention task. Their responses while looking at their rejecter included love, despair, good, and bad memories, and wondering why this happened. Activation specific to the image of the beloved occurred in areas associated with gains and losses, craving and emotion regulation and included the ventral tegmental area (VTA) bilaterally, ventral striatum, medial and lateral orbitofrontal/prefrontal cortex, and cingulate gyrus. Compared with data from happily-in-love individuals, the regional VTA activation suggests that mesolimbic reward/survival systems are involved in romantic passion regardless of whether one is happily or unhappily in love. Forebrain activations associated with motivational relevance, gain/loss, cocaine craving, addiction, and emotion regulation suggest that higher-order systems subject to experience and learning also may mediate the rejection reaction. The results show activation of reward systems, previously identified by monetary stimuli, in a natural, endogenous, negative emotion state. Activation of areas involved in cocaine addiction may help explain the obsessive behaviors associated with rejection in love.

Affirmative Action Plans, January 1, 1994--December 31, 1994. Revision

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-02-16

This document is the Affirmative Action Plan for January 1, 1994 through December 31, 1994 for the Lawrence Berkeley Laboratory, University of California (``LBL`` or ``the Laboratory.``) This is an official document that will be presented upon request to the Office of Federal Contract Compliance Programs, US Department of Labor. The plan is prepared in accordance with the Executive Order 11246 and 41 CFR Section 60-1 et seq. covering equal employment opportunity and will be updated during the year, if appropriate. Analyses included in this volume as required by government regulations are based on statistical comparisons. All statistical comparisons involvemore » the use of geographic areas and various sources of statistics. The geographic areas and sources of statistics used here are in compliance with the government regulations, as interpreted. The use of any geographic area or statistic does not indicate agreement that the geographic area is the most appropriate or that the statistic is the most relevant. The use of such geographic areas and statistics is intended to have no significance outside the context of this Affirmative Action Plan, although, of course, such statistics and geographic areas will be used in good faith with respect to this Affirmative Action Plan.« less

Dinophysis Toxins: Causative Organisms, Distribution and Fate in Shellfish

PubMed Central

Reguera, Beatriz; Riobó, Pilar; Rodríguez, Francisco; Díaz, Patricio A.; Pizarro, Gemita; Paz, Beatriz; Franco, José M.; Blanco, Juan

2014-01-01

Several Dinophysis species produce diarrhoetic toxins (okadaic acid and dinophysistoxins) and pectenotoxins, and cause gastointestinal illness, Diarrhetic Shellfish Poisoning (DSP), even at low cell densities (<103 cells·L−1). They are the main threat, in terms of days of harvesting bans, to aquaculture in Northern Japan, Chile, and Europe. Toxicity and toxin profiles are very variable, more between strains than species. The distribution of DSP events mirrors that of shellfish production areas that have implemented toxin regulations, otherwise misinterpreted as bacterial or viral contamination. Field observations and laboratory experiments have shown that most of the toxins produced by Dinophysis are released into the medium, raising questions about the ecological role of extracelular toxins and their potential uptake by shellfish. Shellfish contamination results from a complex balance between food selection, adsorption, species-specific enzymatic transformations, and allometric processes. Highest risk areas are those combining Dinophysis strains with high cell content of okadaates, aquaculture with predominance of mytilids (good accumulators of toxins), and consumers who frequently include mussels in their diet. Regions including pectenotoxins in their regulated phycotoxins will suffer from much longer harvesting bans and from disloyal competition with production areas where these toxins have been deregulated. PMID:24447996

Demographics, training, and practice patterns of practitioners of folk medicine in Taiwan: a survey of the Taipei metropolitan area.

PubMed

Tsai, Pei-Shan; Lee, Pi-Hsia; Wang, Mei-Yeh

2008-12-01

The purpose of this study was to investigate the demographics, training, and practice patterns of folk medicine practitioners, their opinions toward statutory regulation of folk medicine, and the formal education and credentialing for folk medicine providers in the metropolitan Taipei area. A cross-sectional survey design was used. Included in the survey were 200 folk medicine practitioners in Taipei city and 200 folk medicine practitioners in Taipei county. The survey questionnaire consisted of 3 domains including demographics and training; practice patterns; and opinions toward statutory regulation of folk medicine and formal education and credentialing for Tuina, Ba Guan, Gua Sha, and reflexology providers. The response rates ranged from 86.3% to 99.5%. A typical folk medicine provider in the Taipei metropolitan area was a middle-aged man with a high school degree who worked about 50 hours a week. The majority of the providers in the Taipei metropolitan area received their training through apprenticeship. Years of training and experience varied widely among these practitioners. About 80% had received more than one year of training prior to starting their practice. Adult men and women were their major clientele. The major treatment modalities they offered were Tuina, Gua Sha, Ba Guan, reflexology, and meridian massage. The majority of the respondents agreed that practitioners should receive formal education and training and agreed that certifying the qualifications of folk medicine practitioners is necessary. Findings from the present survey provide an understanding of the training and practice patterns of Taiwanese folk medicine practitioners, highlight folk medicine practitioners' needs for formal education and training, and stress the importance of statutory regulation of folk medicine in Taiwan.

33 CFR 165.1171 - Copper Canyon, Lake Havasu, Colorado River-Regulated Navigation Area.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Copper Canyon, Lake Havasu... Guard District § 165.1171 Copper Canyon, Lake Havasu, Colorado River—Regulated Navigation Area. (a) Location. The following is a regulated navigation area: (1) In the water area of Copper Canyon, Lake Havasu...

33 CFR 165.1171 - Copper Canyon, Lake Havasu, Colorado River-Regulated Navigation Area.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Copper Canyon, Lake Havasu... Guard District § 165.1171 Copper Canyon, Lake Havasu, Colorado River—Regulated Navigation Area. (a) Location. The following is a regulated navigation area: (1) In the water area of Copper Canyon, Lake Havasu...

Essential Components of a Perimeter Air Monitoring Plan and Worker Protection Program at Sites Involving the Excavation of Naturally Occurring Asbestos (NOA) in California

NASA Astrophysics Data System (ADS)

Zdeb, T. F.

2012-12-01

Preparing a Perimeter Air Monitoring Plan that provides the essential information and methods of evaluation needed to assure that the health of the surrounding community is adequately protected and adapting currently existing Cal/OSHA regulations to be relevant to the protection of workers at sites involving the excavation of Naturally Occurring Asbestos (NOA) is oftentimes challenging in California. Current guidelines regarding what constitutes an effective air monitoring program are often lacking in details regarding what should be sampled and analyzed to characterize a site and what evaluation techniques should be applied to process the results of monitoring, and the current Cal/OSHA asbestos related regulations regarding worker protection are for the most part largely pertinent to the abatement of asbestos in buildings. An overview of the essential components of an effective Baseline and Perimeter Air Monitoring Plan will be presented that includes a brief discussion of the various asbestos types and fiber sizes that may need to be considered, possible approachs for evaluating temporal and spatial variability, review of selected site boundary target concentrations, and consideration of the potential for airborne dust and soil containing asbestos (and other contaminants) to migrate and accumulate offsite eventually contributing to "background creep" --the incremental increase of overall airborne asbestos concentrations in the areas surrounding the site due to the re-entrainment of asbestos from the settled dust and/or transported soil. In addition to the above, the current Cal/OSHA asbestos regulations related to worker protection will be briefly discussed with respect to their relevancy at NOA sites with an overview of the adaptations to the regulations that were developed as a result of some fairly lengthy discussions with representatives of Cal/OSHA. These adaptations include, among other things, defining how regulated areas (asbestos concentrations over 1%) and "provisionally regulated" areas (less than 1%) are established and treated, what variables need to be considered when attempting to complete a personal exposure assessment, Cal/OSHA Permissible Exposure Limits (PELs) versus site specific permissible exposure limits, allowable work practices, and the qualifications of personnel performing the sampling and analyses of data.

Gentle on the Land.

ERIC Educational Resources Information Center

Baker, Beth

1998-01-01

Describes the environmental program of East Kentucky Power Co-op, which has included an extensive biological survey of power line corridors, related environmental education in area schools, recycling activities, innovative techniques to meet clear air and water regulations, harvesting rare plant seeds and distributing them to schools and youth…

Cable Television Franchise Provisions for Schools.

ERIC Educational Resources Information Center

National Education Association, Washington, DC. Div. of Instruction and Professional Development.

The National Educational Association (NEA) makes recommendations on the services of franchised cable television stations to schools. The recommendations, in 20 areas, are then compared with existing Federal Communications Commission (FCC) regulations on each point. The recommendations include: a minimum of at least one educational access channel…

33 CFR 165.1301 - Puget Sound and Adjacent Waters in Northwestern Washington-Regulated Navigation Area.

Code of Federal Regulations, 2010 CFR

2010-07-01

... and shapes required by Part 81 of this title (72 COLREGS), display at the end of the net most distant... displayed from at least three feet above the surface of the water. (3) Vessels engaged in fishing, including...

Science Safety Procedure Handbook.

ERIC Educational Resources Information Center

Lynch, Mervyn A.; Offet, Lorna

This booklet outlines general safety procedures in the areas of: (1) student supervision; (2) storage safety regulations, including lists of incompatible chemicals, techniques of disposal and storage; (3) fire; and (4) first aid. Specific sections exist for elementary, junior high school, senior high school, in which special procedures are…

7 CFR 4284.3 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... programs so identified in USDA regulations. Economic development—The economic growth of an area as..., increased duration of employment, higher wage levels, or gains in other measurements of economic activity... institution, including an accredited institution of higher education, no part of the net earnings of which may...

7 CFR 4284.3 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... programs so identified in USDA regulations. Economic development—The economic growth of an area as..., increased duration of employment, higher wage levels, or gains in other measurements of economic activity... institution, including an accredited institution of higher education, no part of the net earnings of which may...

7 CFR 301.75-9 - Interstate movement of regulated articles from a quarantined area for experimental or scientific...

Code of Federal Regulations, 2011 CFR

2011-01-01

... Interstate movement of regulated articles from a quarantined area for experimental or scientific purposes. A... 7 Agriculture 5 2011-01-01 2011-01-01 false Interstate movement of regulated articles from a quarantined area for experimental or scientific purposes. 301.75-9 Section 301.75-9 Agriculture Regulations of...

7 CFR 301.75-9 - Interstate movement of regulated articles from a quarantined area for experimental or scientific...

Code of Federal Regulations, 2010 CFR

2010-01-01

... Interstate movement of regulated articles from a quarantined area for experimental or scientific purposes. A... 7 Agriculture 5 2010-01-01 2010-01-01 false Interstate movement of regulated articles from a quarantined area for experimental or scientific purposes. 301.75-9 Section 301.75-9 Agriculture Regulations of...

Dopamine, the medial preoptic area, and male sexual behavior.

PubMed

Dominguez, Juan M; Hull, Elaine M

2005-10-15

The medial preoptic area (MPOA), at the rostral end of the hypothalamus, is important for the regulation of male sexual behavior. Results showing that male sexual behavior is impaired following MPOA lesions and enhanced with MPOA stimulation support this conclusion. The neurotransmitter dopamine (DA) facilitates male sexual behavior in all studied species, including rodents and humans. Here, we review data indicating that the MPOA is one site where DA may act to regulate male sexual behavior. DA agonists microinjected into the MPOA facilitate sexual behavior, whereas DA antagonists impair copulation, genital reflexes, and sexual motivation. Moreover, microdialysis experiments showed increased release of DA in the MPOA as a result of precopulatory exposure to an estrous female and during copulation. DA may remove tonic inhibition in the MPOA, thereby enhancing sensorimotor integration, and also coordinate autonomic influences on genital reflexes. In addition to sensory stimulation, other factors influence the release of DA in the MPOA, including testosterone, nitric oxide, and glutamate. Here we summarize and interpret these data.

Focal exposure of limited lung volumes to high-dose irradiation down-regulated organ development-related functions and up-regulated the immune response in mouse pulmonary tissues.

PubMed

Kim, Bu-Yeo; Jin, Hee; Lee, Yoon-Jin; Kang, Ga-Young; Cho, Jaeho; Lee, Yun-Sil

2016-01-27

Despite the emergence of stereotactic body radiotherapy (SBRT) for treatment of medically inoperable early-stage non-small-cell lung cancer patients, the molecular effects of focal exposure of limited lung volumes to high-dose radiation have not been fully characterized. This study was designed to identify molecular changes induced by focal high-dose irradiation using a mouse model of SBRT. Central areas of the mouse left lung were focally-irradiated (3 mm in diameter) with a single high-dose of radiation (90 Gy). Temporal changes in gene expression in the irradiated and non-irradiated neighboring lung regions were analyzed by microarray. For comparison, the long-term effect (12 months) of 20 Gy radiation on a diffuse region of lung was also measured. The majority of genes were down-regulated in the focally-irradiated lung areas at 2 to 3 weeks after irradiation. This pattern of gene expression was clearly different than gene expression in the diffuse region of lungs exposed to low-dose radiation. Ontological and pathway analyses indicated these down-regulated genes were mainly associated with organ development. Although the number was small, genes that were up-regulated after focal irradiation were associated with immune-related functions. The temporal patterns of gene expression and the associated biological functions were also similar in non-irradiated neighboring lung regions, although statistical significance was greatly reduced when compared with those from focally-irradiated areas of the lung. From network analysis of temporally regulated genes, we identified inter-related modules associated with diverse functions, including organ development and the immune response, in both the focally-irradiated regions and non-irradiated neighboring lung regions. Focal exposure of lung tissue to high-dose radiation induced expression of genes associated with organ development and the immune response. This pattern of gene expression was also observed in non-irradiated neighboring areas of lung tissue, indicating a global lung response to focal high-dose irradiation.

Presynaptic Regulation of Leptin in a Defined Lateral Hypothalamus-Ventral Tegmental Area Neurocircuitry Depends on Energy State.

PubMed

Liu, Jing-Jing; Bello, Nicholas T; Pang, Zhiping P

2017-12-06

Synaptic transmission controls brain activity and behaviors, including food intake. Leptin, an adipocyte-derived hormone, acts on neurons located in the lateral hypothalamic area (LHA) to maintain energy homeostasis and regulate food intake behavior. The specific synaptic mechanisms, cell types, and neural projections mediating this effect remain unclear. In male mice, using pathway-specific retrograde tracing, whole-cell patch-clamp recordings and post hoc cell type identification, we found that leptin reduces excitatory synaptic strength onto both melanin-concentrating hormone- and orexin-expressing neurons projecting from the LHA to the ventral tegmental area (VTA), which may affect dopamine signaling and motivation for feeding. A presynaptic mechanism mediated by distinct intracellular signaling mechanisms may account for this regulation by leptin. The regulatory effects of leptin depend on intact leptin receptor signaling. Interestingly, the synaptic regulatory function of leptin in the LHA-to-VTA neuronal pathway is highly sensitive to energy states: both energy deficiency (acute fasting) and excessive energy storage (high-fat diet-induced obesity) blunt the effect of leptin. These data revealed that leptin may regulate synaptic transmission in the LHA-to-VTA neurocircuitry in an inverted "U-shape" fashion dependent on plasma glucose levels and related to metabolic states. SIGNIFICANCE STATEMENT The lateral hypothalamic area (LHA) to ventral tegmental area (VTA) projection is an important neural pathway involved in balancing whole-body energy states and reward. We found that the excitatory synaptic inputs to both orexin- and melanin-concentrating hormone expressing LHA neurons projecting to the VTA were suppressed by leptin, a peptide hormone derived from adipocytes that signals peripheral energy status to the brain. Interestingly, energy states seem to affect how leptin regulates synaptic transmission since both the depletion of energy induced by acute food deprivation and excessive storage of energy by high-fat diet feeding dampen the suppressive effect of leptin on synaptic transmission. Together, these data show that leptin regulates synaptic transmission and might be important for maintaining energy homeostasis. Copyright © 2017 the authors 0270-6474/17/3711854-13$15.00/0.

The neural correlates of regulating another person's emotions: an exploratory fMRI study

PubMed Central

Hallam, Glyn P.; Webb, Thomas L.; Sheeran, Paschal; Miles, Eleanor; Niven, Karen; Wilkinson, Iain D.; Hunter, Michael D.; Woodruff, Peter W. R.; Totterdell, Peter; Farrow, Tom F. D.

2014-01-01

Studies investigating the neurophysiological basis of intrapersonal emotion regulation (control of one's own emotional experience) report that the frontal cortex exerts a modulatory effect on limbic structures such as the amygdala and insula. However, no imaging study to date has examined the neurophysiological processes involved in interpersonal emotion regulation, where the goal is explicitly to regulate another person's emotion. Twenty healthy participants (10 males) underwent fMRI while regulating their own or another person's emotions. Intrapersonal and interpersonal emotion regulation tasks recruited an overlapping network of brain regions including bilateral lateral frontal cortex, pre-supplementary motor area, and left temporo-parietal junction. Activations unique to the interpersonal condition suggest that both affective (emotional simulation) and cognitive (mentalizing) aspects of empathy may be involved in the process of interpersonal emotion regulation. These findings provide an initial insight into the neural correlates of regulating another person's emotions and may be relevant to understanding mental health issues that involve problems with social interaction. PMID:24936178

7 CFR 301.55-4 - Conditions governing the interstate movement of regulated articles from quarantined areas.

Code of Federal Regulations, 2010 CFR

2010-01-01

... from outside the quarantined area that are being moved in accordance with the protocols described in a... movement of regulated articles from quarantined areas. Any regulated article may be moved interstate from a quarantined area 3 only if moved under the following conditions: 3 Requirements under all other applicable...

9 CFR 83.4 - VHS-regulated fish and VHS-regulated areas.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false VHS-regulated fish and VHS-regulated... HEMORRHAGIC SEPTICEMIA § 83.4 VHS-regulated fish and VHS-regulated areas. (a)(1) APHIS will list as a VHS-regulated fish any fish species found in freshwater to be susceptible to the North American (type IV) strain...

Spatially Distributed Assimilation of Remotely Sensed Leaf Area Index and Potential Evapotranspiration for Hydrologic Modeling in Wetland Landscapes

EPA Science Inventory

Evapotranspiration (ET), a highly dynamic flux in wetland landscapes, regulates the accuracy of surface/sub-surface runoff simulation in a hydrologic model. However, considerable uncertainty in simulating ET-related processes remains, including our limited ability to incorporate ...

Connecting Latinos with nature

Treesearch

Deborah J. Chavez

2008-01-01

Experts around the world have identified ecosystem services that benefit humans. Ecosystem services provided by natural areas include cultural (such as providing outdoor recreation locations) and regulating (such as protecting water quality) services. It is important to understand both public perceptions about the importance of particular ecosystem services and the...

The Federal Program in Population Research, Parts 1 and 2.

ERIC Educational Resources Information Center

Federal Council for Science and Technology, Washington, DC.

The first part of this report characterizes the many facets of the population problem (including biological, economic, and social aspects), suggests a list of areas in which the Federal Government should emphasize research (reproductive biology; fertility regulation techniques and materials; description, determinants, consequences of population…

15 CFR 922.164 - Additional activity regulations by Sanctuary area.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., breaking, cutting, spearing or similarly injuring any coral or other marine invertebrate, or any plant... injuring any coral, marine invertebrate, fish, bottom formation, algae, seagrass or other living or dead organism, including shells, or attempting any of these activities. However, fish, invertebrates, and marine...

45 CFR 1304.52 - Human resources management.

Code of Federal Regulations, 2010 CFR

2010-10-01

... supported by staff or consultants with training and experience in areas that include: The theories and... group. However, if State, Tribal or local regulations specify staff:child ratios and group sizes more... theories and principles of child growth and development, early childhood education (birth to age five), and...

EXPLOITING GENOME DATA TO UNDERSTAND THE FUNCTION, REGULATION AND EVOLUTIONARY ORIGINS OF TOXICOLOGICALLY RELEVANT GENES

EPA Science Inventory

The wealth of new information coming from the many genome sequencing projects is providing unprecedented opportunities for major advances in all areas of biology, including the environmental health sciences. To facilitate this discovery process, experts in the fields of function...

Controlling Urban Air Pollution: A Benefit-Cost Assessment.

ERIC Educational Resources Information Center

Krupnick, Alan J.; Portney, Paul R.

1991-01-01

The pros and cons of air pollution control efforts are discussed. Both national and regional air pollution control plans are described. Topics of discussion include benefit-cost analysis, air quality regulation, reducing ozone in the urban areas, the Los Angeles plan, uncertainties, and policy implications. (KR)

Effect of aging on microRNAs and regulation of pathogen recognition receptors

PubMed Central

Olivieri, Fabiola; Procopio, Antonio Dormenico

2014-01-01

Immunosenescence is the multifactorial age-associated immune deteriorization that leads to increased susceptibility to infections and decreased responses to vaccines. Recent studies have shown a fundamental role for microRNAs (miRNAs) in regulating immune responses, and nearly all the miRNAs involved in immune regulation show modulation during aging. Aging-associated miRNAs are largely negative regulators of the immune innate response and target central nodes of aging-associated networks, in particular, NF-κB, the downstream effector of TLR signals that leads to induction of proinflammatory responses. Multiple miRNAs have been reported to share similar regulatory activity. Here we review miRNA regulation of human innate immune recognition in aging, including both activation and resolution of inflammation, critical issues in detection, and areas of active investigation into our understanding of immunosenescence. PMID:24769423

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boing, L.E.

This paper presents an overview of the US experiences in the decommissioning technical area. Sections included are: (1) an overview of the magnitude of the problem, (2) a review of the US decommissioning process, (3) regulation of decommissioning, (4) regulatory and funding requirements for decommissioning, and (5) a general overview of all on-going and completed decommissioning projects to date in the US. The final section presents a review of some issues in the decommissioning area currently being debated in the technical specialists community.

Regression Equations for Estimating Flood Flows at Selected Recurrence Intervals for Ungaged Streams in Pennsylvania

USGS Publications Warehouse

Roland, Mark A.; Stuckey, Marla H.

2008-01-01

Regression equations were developed for estimating flood flows at selected recurrence intervals for ungaged streams in Pennsylvania with drainage areas less than 2,000 square miles. These equations were developed utilizing peak-flow data from 322 streamflow-gaging stations within Pennsylvania and surrounding states. All stations used in the development of the equations had 10 or more years of record and included active and discontinued continuous-record as well as crest-stage partial-record stations. The state was divided into four regions, and regional regression equations were developed to estimate the 2-, 5-, 10-, 50-, 100-, and 500-year recurrence-interval flood flows. The equations were developed by means of a regression analysis that utilized basin characteristics and flow data associated with the stations. Significant explanatory variables at the 95-percent confidence level for one or more regression equations included the following basin characteristics: drainage area; mean basin elevation; and the percentages of carbonate bedrock, urban area, and storage within a basin. The regression equations can be used to predict the magnitude of flood flows for specified recurrence intervals for most streams in the state; however, they are not valid for streams with drainage areas generally greater than 2,000 square miles or with substantial regulation, diversion, or mining activity within the basin. Estimates of flood-flow magnitude and frequency for streamflow-gaging stations substantially affected by upstream regulation are also presented.

9 CFR 83.4 - VHS-regulated fish and VHS-regulated areas.

Code of Federal Regulations, 2014 CFR

2014-01-01

... VHS virus, with confirmation of strain identity through genetic sequencing. Anadromous fish that have... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false VHS-regulated fish and VHS-regulated... HEMORRHAGIC SEPTICEMIA § 83.4 VHS-regulated fish and VHS-regulated areas. (a)(1) APHIS will list as a VHS...

33 CFR 165.840 - Regulated Navigation Area, Gulf of Mexico: Mississippi Canyon Block 20, South of New Orleans, LA.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Regulated Navigation Area, Gulf of Mexico: Mississippi Canyon Block 20, South of New Orleans, LA. 165.840 Section 165.840 Navigation... Limited Access Areas Eighth Coast Guard District § 165.840 Regulated Navigation Area, Gulf of Mexico...

33 CFR 165.840 - Regulated Navigation Area, Gulf of Mexico: Mississippi Canyon Block 20, South of New Orleans, LA.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Regulated Navigation Area, Gulf of Mexico: Mississippi Canyon Block 20, South of New Orleans, LA. 165.840 Section 165.840 Navigation... Limited Access Areas Eighth Coast Guard District § 165.840 Regulated Navigation Area, Gulf of Mexico...

33 CFR 165.838 - Regulated Navigation Area; New Orleans Area of Responsibility, New Orleans, LA.

Code of Federal Regulations, 2012 CFR

2012-07-01

... the RNA, or as authorized by a waiver approved by the COTP in accordance with paragraph (d) of this... as the malfunction of a bridge or lock within the RNA, the person in charge of a vessel may orally.... (a) Regulated Navigation Area. The following is a regulated navigation area (RNA): (1) The Inner...

33 CFR 165.838 - Regulated Navigation Area; New Orleans Area of Responsibility, New Orleans, LA.

Code of Federal Regulations, 2010 CFR

2010-07-01

... the RNA, or as authorized by a waiver approved by the COTP in accordance with paragraph (d) of this... as the malfunction of a bridge or lock within the RNA, the person in charge of a vessel may orally.... (a) Regulated Navigation Area. The following is a regulated navigation area (RNA): (1) The Inner...

33 CFR 165.838 - Regulated Navigation Area; New Orleans Area of Responsibility, New Orleans, LA.

Code of Federal Regulations, 2013 CFR

2013-07-01

... the RNA, or as authorized by a waiver approved by the COTP in accordance with paragraph (d) of this... as the malfunction of a bridge or lock within the RNA, the person in charge of a vessel may orally.... (a) Regulated Navigation Area. The following is a regulated navigation area (RNA): (1) The Inner...

33 CFR 165.838 - Regulated Navigation Area; New Orleans Area of Responsibility, New Orleans, LA.

Code of Federal Regulations, 2011 CFR

2011-07-01

... the RNA, or as authorized by a waiver approved by the COTP in accordance with paragraph (d) of this... as the malfunction of a bridge or lock within the RNA, the person in charge of a vessel may orally.... (a) Regulated Navigation Area. The following is a regulated navigation area (RNA): (1) The Inner...

Multi-scale computational study of the mechanical regulation of cell mitotic rounding in epithelia

PubMed Central

Xu, Zhiliang; Zartman, Jeremiah J.; Alber, Mark

2017-01-01

Mitotic rounding during cell division is critical for preventing daughter cells from inheriting an abnormal number of chromosomes, a condition that occurs frequently in cancer cells. Cells must significantly expand their apical area and transition from a polygonal to circular apical shape to achieve robust mitotic rounding in epithelial tissues, which is where most cancers initiate. However, how cells mechanically regulate robust mitotic rounding within packed tissues is unknown. Here, we analyze mitotic rounding using a newly developed multi-scale subcellular element computational model that is calibrated using experimental data. Novel biologically relevant features of the model include separate representations of the sub-cellular components including the apical membrane and cytoplasm of the cell at the tissue scale level as well as detailed description of cell properties during mitotic rounding. Regression analysis of predictive model simulation results reveals the relative contributions of osmotic pressure, cell-cell adhesion and cortical stiffness to mitotic rounding. Mitotic area expansion is largely driven by regulation of cytoplasmic pressure. Surprisingly, mitotic shape roundness within physiological ranges is most sensitive to variation in cell-cell adhesivity and stiffness. An understanding of how perturbed mechanical properties impact mitotic rounding has important potential implications on, amongst others, how tumors progressively become more genetically unstable due to increased chromosomal aneuploidy and more aggressive. PMID:28531187

33 CFR 165.13 - General regulations.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false General regulations. 165.13... Areas § 165.13 General regulations. (a) The master of a vessel in a regulated navigation area shall operate the vessel in accordance with the regulations contained in Subpart F. (b) No person may cause or...

The self-regulated learning of medical students in the clinical environment - a scoping review.

PubMed

Cho, Kenneth K; Marjadi, Brahm; Langendyk, Vicki; Hu, Wendy

2017-07-10

Self-regulated learning is the individual's ability to effectively use various strategies to reach their learning goals. We conducted this scoping review to explore what has been found regarding self-regulated learning in the clinical environment and how this was measured. Using Arksey and O'Malley's five-stage framework, we searched three medical and educational databases as well as Google Scholar for literature on the self-regulated learning of medical students in the clinical environment published between 1966 and February 2017. After results were screened and relevant studies were identified, the data was summarised and discursively reported. The search resulted in 911 articles, with 14 articles included in the scoping review after the inclusion criteria was applied. Self-regulated learning was explored in these studies in various ways including qualitative, quantitative and mixed methods. Three major findings were found: 1) levels of self-regulated learning change in the clinical environment, 2) self-regulated learning is associated with academic achievement, success in clinical skills and mental health and 3) various factors can support self-regulated learning levels in medical students. Most of articles exploring the self-regulated learning of medical students during the clinical years have been published in the last 5 years, suggesting a growing interest in the area. Future research could explore the self-regulated learning levels of medical students during the clinical years using a longitudinal approach or through the use of novel qualitative approaches.

Strategies for restoration of deep-water coral ecosystems based on a global survey of oil and gas regulations

NASA Astrophysics Data System (ADS)

Cordes, E. E.; Jones, D.; Levin, L. A.

2016-02-01

The oil and gas industry is one of the most active agents of the global industrialization of the deep sea. The wide array of impacts following the Deepwater Horizon oil spill highlighted the need for a systematic review of existing regulations both in US waters and internationally. Within different exclusive economic zones, there are a wide variety of regulations regarding the survey of deep-water areas prior to leasing and the acceptable set-back distances from vulnerable marine ecosystems once they are discovered. There are also varying mitigation strategies for accidental release of oil and gas, including active monitoring systems, temporary closings of oil and gas production, and marine protected areas. The majority of these regulations are based on previous studies of typical impacts from oil and gas drilling, rather than accidental releases. However, the probability of an accident from standard operations increases significantly with depth. The Oil & Gas working group of the Deep Ocean Stewardship Initiative is an international partnership of scientists, managers, non-governmental organizations, and industry professionals whose goal is to review existing regulations for the oil & gas industry and produce a best practices document to advise both developed and developing nations on their regulatory structure as energy development moves into deeper waters.

Revolting Developments in Our Understanding of the Organization of the Eukaryotic Genome.

ERIC Educational Resources Information Center

Krider, Hallie M.

1984-01-01

Various typs of DNA are discussed. Areas considered include highly repetitive and satellite sequences, genes encoding, ribosomal RNA, histone protein genes, and dispersed repeated genes that jump. Regulated genetic misbehavior, structure and use of unique genes, and higher order complexities of chromosomes are also discussed. (JN)

30 CFR 75.372 - Mine ventilation map.

Code of Federal Regulations, 2010 CFR

2010-07-01

... at each opening. (8) The elevation at the top and bottom of each shaft and slope, and shaft and slope... of all ventilation controls, including permanent stoppings, overcasts, undercasts, regulators, seals... seals for each worked-out area. (19) The entry height, velocity and direction of the air current at or...

15 CFR 923.24 - Shorefront access and protection planning.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 15 Commerce and Foreign Trade 3 2013-01-01 2013-01-01 false Shorefront access and protection... COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Special Management Areas § 923.24 Shorefront access and protection planning. (a) The management program must include a definition of the term...

15 CFR 923.24 - Shorefront access and protection planning.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Shorefront access and protection... COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Special Management Areas § 923.24 Shorefront access and protection planning. (a) The management program must include a definition of the term...

15 CFR 923.24 - Shorefront access and protection planning.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 15 Commerce and Foreign Trade 3 2012-01-01 2012-01-01 false Shorefront access and protection... COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Special Management Areas § 923.24 Shorefront access and protection planning. (a) The management program must include a definition of the term...

15 CFR 923.24 - Shorefront access and protection planning.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 15 Commerce and Foreign Trade 3 2011-01-01 2011-01-01 false Shorefront access and protection... COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Special Management Areas § 923.24 Shorefront access and protection planning. (a) The management program must include a definition of the term...

15 CFR 923.24 - Shorefront access and protection planning.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 15 Commerce and Foreign Trade 3 2014-01-01 2014-01-01 false Shorefront access and protection... COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Special Management Areas § 923.24 Shorefront access and protection planning. (a) The management program must include a definition of the term...

Transborder Flow of Computerized Information: Controls and Restrictions.

ERIC Educational Resources Information Center

Shrader, Erwin

Of major concern to United States position and policy in the telecommunications and information areas is "transborder data flow," the transferring of computer stored data between nations. Many European nations, including France, Austria, and West Germany, have enacted laws regulating the flow of information leaving the country where it…

77 FR 40938 - Pilot Program on NAFTA Trucking Provisions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-11

... regulations is included in 49 CFR part 385, Appendix B, Section VII. Parts of the FMCSRs and HMRs having similar characteristics are combined together into six regulatory areas called ``factors.'' The regulatory factors are intended to evaluate the adequacy of a carrier's management controls. M. Passed Phase 1...

32 CFR 552.87 - General.

Code of Federal Regulations, 2010 CFR

2010-07-01

... or using DPCA recreational areas (appendix A) are not required to possess a permit. Travel to and... roads, and direct trail access. Other travel in the range complex is governed by this regulation. (3... for land, including Scout Camporees, seasonal or one-time regional meets, and so on, must apply to the...

Applied Science and Research Applications: Recent Research Reports.

ERIC Educational Resources Information Center

National Science Foundation, Washington, DC. Directorate for Applied Science and Research Applications.

This report contains abstracts of new technical reports and other documents resulting from research supported by the directorate for Applied Science and Research Applications of the National Science Foundation. Research reports from current programs include work in the areas of public policy and regulation; public service delivery and urban…

Ecosystem services: Just another catch phrase?

Treesearch

Emily Weidner

2011-01-01

The "ecosystem services" concept has emerged as a popular area of discussion among policy makers and conservation advocates. Ecosystem services are the benefits people derive from nature and include the provision of water, food, wood, and fiber; regulation of climate, flood, drought, and disease; maintenance of biodiversity; and recreational, aesthetic,...

77 FR 32918 - Airworthiness Directives; The Boeing Company Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-04

... require repetitive inspections for cracks and a chemical spot test in the area of station (STA) 908, and.... We will post all comments we receive, without change, to http://www.regulations.gov , including any personal information you provide. We will also post a report summarizing each substantive verbal contact we...

15 CFR 946.7 - Preparation of proposed certification for restructuring.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REGULATIONS OF THE NATIONAL WEATHER SERVICE MODERNIZATION OF THE NATIONAL WEATHER SERVICE § 946.7 Preparation... certification shall include: (1) A description of local weather characteristics and weather-related concerns which affect the weather services provided within the service area; (2) A detailed comparison of the...

15 CFR 946.7 - Preparation of proposed certification for restructuring.

Code of Federal Regulations, 2011 CFR

2011-01-01

... REGULATIONS OF THE NATIONAL WEATHER SERVICE MODERNIZATION OF THE NATIONAL WEATHER SERVICE § 946.7 Preparation... certification shall include: (1) A description of local weather characteristics and weather-related concerns which affect the weather services provided within the service area; (2) A detailed comparison of the...

15 CFR 946.7 - Preparation of proposed certification for restructuring.

Code of Federal Regulations, 2012 CFR

2012-01-01

... REGULATIONS OF THE NATIONAL WEATHER SERVICE MODERNIZATION OF THE NATIONAL WEATHER SERVICE § 946.7 Preparation... certification shall include: (1) A description of local weather characteristics and weather-related concerns which affect the weather services provided within the service area; (2) A detailed comparison of the...

15 CFR 946.7 - Preparation of proposed certification for restructuring.

Code of Federal Regulations, 2013 CFR

2013-01-01

... REGULATIONS OF THE NATIONAL WEATHER SERVICE MODERNIZATION OF THE NATIONAL WEATHER SERVICE § 946.7 Preparation... certification shall include: (1) A description of local weather characteristics and weather-related concerns which affect the weather services provided within the service area; (2) A detailed comparison of the...

15 CFR 946.7 - Preparation of proposed certification for restructuring.

Code of Federal Regulations, 2014 CFR

2014-01-01

... REGULATIONS OF THE NATIONAL WEATHER SERVICE MODERNIZATION OF THE NATIONAL WEATHER SERVICE § 946.7 Preparation... certification shall include: (1) A description of local weather characteristics and weather-related concerns which affect the weather services provided within the service area; (2) A detailed comparison of the...

15 CFR 922.154 - Consultation with the State of Washington, affected Indian tribes, and adjacent county governments.

Code of Federal Regulations, 2010 CFR

2010-01-01

... SANCTUARY PROGRAM REGULATIONS Olympic Coast National Marine Sanctuary § 922.154 Consultation with the State... the Sanctuary, and adjacent county governments regarding areas of mutual concern, including Sanctuary programs, permitting, activities, development, and threats to Sanctuary resources. (b) The Director shall...

9 CFR 94.5 - Regulation of certain garbage.

Code of Federal Regulations, 2010 CFR

2010-01-01

.... Cooking garbage at an internal temperature of 212 °F for 30 minutes. Stores. The food, supplies, and other... in this section and includes food scraps, table refuse, galley refuse, food wrappers or packaging materials, and other waste material from stores, food preparation areas, passengers' or crews' quarters...

40 CFR 52.1606 - Visibility protection.

Code of Federal Regulations, 2011 CFR

2011-07-01

... include approvable procedures meeting the requirements of 40 CFR 51.305 and 51.307 for protection of visibility in mandatory Class I Federal areas. (b) Regulations for visibility monitoring and new source... and made part of the applicable plan for the State of New Jersey. [51 FR 23759, July 1, 1986, as...

A Multidimensional Needs Assessment of Social Emotional Learning Skill Areas

ERIC Educational Resources Information Center

Yopp, Ashley; McKim, Billy R.; Moore, Lori L.; Odom, Summer F.; Hanagriff, Roger

2017-01-01

Social and Emotional Learning (SEL) has often been an umbrella term for a wide range of competencies, including emotional processes, social and interpersonal skills, and cognitive regulation (Jones, Bouffard, & Weissbourd, 2013). We used the Borich (1980) needs assessment model to assess the professional development needs of Texas agricultural…

Retigabine ameliorates acute stress-induced impairment of spatial memory retrieval through regulating USP2 signaling pathways in hippocampal CA1 area.

PubMed

Li, Cai; Zhang, Ji; Xu, Haiwei; Chang, Mujun; Lv, Chuntao; Xue, Wenhua; Song, Zhizhen; Zhang, Lizhen; Zhang, Xiaojian; Tian, Xin

2018-06-01

Acute stress could trigger maladaptive changes associated with stress-related cognitive and emotional deficits. Dysfunction of ion channel or receptor in the hippocampal area has been linked to the cognitive deficits induced by stress. It is known that Kv7 channel openers, including FDA-approved drug retigabine, show cognitive protective efficacy. However, the underlying molecular mechanisms remain elusive. Here we showed that exposing adult male rats to acute stress significantly impaired the spatial memory, a cognitive process controlled by the hippocampus. Concomitantly, significantly reduced AMPA receptor expression was found in hippocampal CA1 area from acute stressed rats. This effect relied on the down-regulation of deubiquitinating enzyme USP2 and its upstream regulators (PGC-1α and β-catenin), and the subsequent enhancement of mTOR-related autophagy which is regulated by USP2. These findings suggested that acute stress dampened AMPA receptor expression by controlling USP2-related signaling, which caused the detrimental effect on hippocampus-dependent cognitive processes. We also found that retigabine alleviated acute stress-induced spatial memory retrieval impairment through adjusting the aberrance of USP2, its upstream regulators (PGC-1α, E4BP4 and β-catenin) and its downstream targets (mTOR, autophagy and GluA1). Our results have identified USP2 as a key molecule that mediates stress-induced spatial memory retrieval impairment, which provides a framework for new druggable targets to conceptually treat stress-associated cognitive deficits. Copyright © 2018 Elsevier Ltd. All rights reserved.

Off-site Emergency Planning at UK Nuclear Licensed Sites.

PubMed

Leonard, Paul; Thomas, Gareth

2017-04-01

Nuclear emergency planning arrangements in the UK are continually kept under review. This work proposes to outline how experience from nuclear exercises and undertaking emergency response duties can be based on radiological knowledge of specific sites and utilised in the future. In 2014, the UK regulator, the Office for Nuclear Regulation (ONR) revised their principles for the determination of off-site emergency planning areas around nuclear sites where predetermined countermeasures and other protection measures are applied to protect those people who may be affected by a radiation emergency. The revised principles also enhanced communication from the nuclear site operators and local authorities to the public. This updated ONR's application of the UK Radiation (Emergency Preparedness and Public Information) Regulations 2001 (REPPIR) http://www.hse.gov.uk/radiation/ionising/reppir.htm, which includes details of minimising potential doses to the public, as well as assessment and reassurance, linked to other concurrent risks such as flooding. ONR undertakes site-specific assessments of each operators' hazard identification and risk evaluation, which include consideration of whether the public might receive a significant radiation dose in the year following the emergency (excluding countermeasures in the first 24 hours). In defining the areas for off-site emergency planning, practical and strategic factors are then considered, which include other local non-nuclear emergency planning arrangements and experience, and whether local geographic and demographic aspects could aid public credibility and confidence. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

76 FR 58105 - Regulated Navigation Area; Saugus River, Lynn, MA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-20

...-AA11 Regulated Navigation Area; Saugus River, Lynn, MA AGENCY: Coast Guard, DHS. ACTION: Temporary... River in Lynn, MA. Establishing this temporary rule will allow the necessary stabilization work to be... on the Energy Systems Pipeline Bridge on the Saugus River in Lynn, MA. The regulated area encompasses...

77 FR 22663 - Asian Longhorned Beetle; Additions to Quarantined Areas in Massachusetts

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-17

... Koelreuteria (golden raintree) to the list of regulated articles. The interim rule, which restricted the interstate movement of regulated articles from these areas, was necessary to prevent the artificial spread of... interstate movement of regulated articles from quarantined areas to prevent the artificial spread of ALB to...

33 CFR 165.T01-0727 - Regulated Navigation Area; Arthur Kill, NY and NJ.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Kill, NY and NJ. 165.T01-0727 Section 165.T01-0727 Navigation and Navigable Waters COAST GUARD... § 165.T01-0727 Regulated Navigation Area; Arthur Kill, NY and NJ. (a) Regulated area. The following area..., and Gulfport Reach in the Arthur Kill; bounded in the northeast by a line drawn from position 40° 38...

33 CFR 165.T01-0727 - Regulated Navigation Area; Arthur Kill, NY and NJ.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Kill, NY and NJ. 165.T01-0727 Section 165.T01-0727 Navigation and Navigable Waters COAST GUARD... § 165.T01-0727 Regulated Navigation Area; Arthur Kill, NY and NJ. (a) Regulated area. The following area..., and Gulfport Reach in the Arthur Kill; bounded in the northeast by a line drawn from position 40° 38...

33 CFR 165.T01-0084 - Regulated Navigation Area; Little Bay Bridge Construction, Little Bay, Portsmouth, NH.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Construction, Little Bay, Portsmouth, NH. (a) Location. The following area is a Regulated Navigation Area (RNA... regulations contained in 33 CFR 165.10, 165.11, and 165.13 apply within the RNA. In addition, the following... vessels must proceed through the area with caution and operate in such a manner as to produce no wake. (4...

33 CFR 165.T01-0084 - Regulated Navigation Area; Little Bay Bridge Construction, Little Bay, Portsmouth, NH.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Construction, Little Bay, Portsmouth, NH. (a) Location. The following area is a Regulated Navigation Area (RNA... regulations contained in 33 CFR 165.10, 165.11, and 165.13 apply within the RNA. In addition, the following... vessels must proceed through the area with caution and operate in such a manner as to produce no wake. (4...

Cognitive emotion regulation enhances aversive prediction error activity while reducing emotional responses.

PubMed

Mulej Bratec, Satja; Xie, Xiyao; Schmid, Gabriele; Doll, Anselm; Schilbach, Leonhard; Zimmer, Claus; Wohlschläger, Afra; Riedl, Valentin; Sorg, Christian

2015-12-01

Cognitive emotion regulation is a powerful way of modulating emotional responses. However, despite the vital role of emotions in learning, it is unknown whether the effect of cognitive emotion regulation also extends to the modulation of learning. Computational models indicate prediction error activity, typically observed in the striatum and ventral tegmental area, as a critical neural mechanism involved in associative learning. We used model-based fMRI during aversive conditioning with and without cognitive emotion regulation to test the hypothesis that emotion regulation would affect prediction error-related neural activity in the striatum and ventral tegmental area, reflecting an emotion regulation-related modulation of learning. Our results show that cognitive emotion regulation reduced emotion-related brain activity, but increased prediction error-related activity in a network involving ventral tegmental area, hippocampus, insula and ventral striatum. While the reduction of response activity was related to behavioral measures of emotion regulation success, the enhancement of prediction error-related neural activity was related to learning performance. Furthermore, functional connectivity between the ventral tegmental area and ventrolateral prefrontal cortex, an area involved in regulation, was specifically increased during emotion regulation and likewise related to learning performance. Our data, therefore, provide first-time evidence that beyond reducing emotional responses, cognitive emotion regulation affects learning by enhancing prediction error-related activity, potentially via tegmental dopaminergic pathways. Copyright © 2015 Elsevier Inc. All rights reserved.

Extent and frequency of floods on the Schuylkill River near Phoenixville and Pottstown, Pennsylvania

USGS Publications Warehouse

Busch, William F.; Shaw, Lewis C.

1973-01-01

Knowledge of the frequency and extent of flooding is an important requirement for the design of all works of man bordering or encroaching on flood plains. The proper design of bridges, culverts, dams, highways, levees, reservoirs, sewage-disposal systems, waterworks and all structures on the flood plains of streams requires careful consideration of flood hazards. -1- By use of relations presented in this report, the extent, depth, and frequency of flooding can be estimated for any site along the reach of the Schuylkill River from Oaks to Pottstown. These flood data are presented so that regulatory agencies, organizations, and individuals may have a technical basis for making decisions on the use of flood-prone areas. The Delaware River Basin Commission and the U. S. Geological Survey regard this program of flood-plain-inundation studies as a positive step toward flood-damage prevention. Flood-plaininundation studies are a prerequisite to flood-plain management which may include a mixture of flood-control structures and/or land-use regulations. Both physical works and flood-plain regulations are included in the Comprehensive Plan for development of the Delaware River basin, of which the Schuylkill River is a part. Recommendations for land use, or suggestions for limitations of land use, are not made herein. Other reports on use and regulation of land in flood-prone areas are available (Dola, 1961; White, 1961; American Society of Civil Engineers Task Force on Flood Plain Regulations, 1962; and Goddard, 1963). The primary responsibility for planning for optimum land use in the flood plain and the implementation of flood-plain zoning or other regulations to achieve such optimum use rests with State, and local interests.

Comparison of International Regulations for Written Medicine Information (WMI) on Prescription Medicines.

PubMed

Yuan, Hsiu-Chun Tony; Raynor, David K; Aslani, Parisa

2018-01-01

This paper presents a review of the literature, including government legislations, policies, guidelines, and recommendations available in the European Union, the United States of America, and Australia pertaining to the availability, development, and distribution of written medicine information (WMI) for prescription medicines. The online databases searched were Embase, International Pharmaceutical Abstracts, Medline, and PubMed, together with Google as the Internet search engine. The design and content of WMI documents have similarities and differences across all the 3 geographical regions. All the 3 regions have legislations in place to evaluate and regulate WMI documents for health care professionals (HCPs) and, to some degree, for patients; however, the degree of regulation varies between the 3 regions. The regulations around the content and information design of WMI impacts how well the WMI performs and consequently influences patients' knowledge and medication-taking behavior. Legislation in certain areas could be seen as more beneficial and can be implemented across the 3 regions. Furthermore, the required legislation on the evaluation of the content of WMIs can be seen in some areas to be more stringent and comprehensive, which when taken onboard across the 3 regions can be valuable when creating WMIs for both patients and HCPs.

Method of Simulating Flow-Through Area of a Pressure Regulator

NASA Technical Reports Server (NTRS)

Hass, Neal E. (Inventor); Schallhorn, Paul A. (Inventor)

2011-01-01

The flow-through area of a pressure regulator positioned in a branch of a simulated fluid flow network is generated. A target pressure is defined downstream of the pressure regulator. A projected flow-through area is generated as a non-linear function of (i) target pressure, (ii) flow-through area of the pressure regulator for a current time step and a previous time step, and (iii) pressure at the downstream location for the current time step and previous time step. A simulated flow-through area for the next time step is generated as a sum of (i) flow-through area for the current time step, and (ii) a difference between the projected flow-through area and the flow-through area for the current time step multiplied by a user-defined rate control parameter. These steps are repeated for a sequence of time steps until the pressure at the downstream location is approximately equal to the target pressure.

The Bittersweet Truth About Sugar Labeling Regulations: They Are Achievable and Overdue

PubMed Central

2012-01-01

The recent Institute of Medicine recommendation to the Food and Drug Administration to include added sugar in a new front-of-package system provides new justification for reviewing outdated regulations pertinent to sugar and analyzing whether the government’s previous resistance to sugar labeling remains valid given new and robust science. I have provided an overview of US sugar consumption, its public health implications, and the science related to added sugar detection. I reviewed US and international sugar intake recommendations and suggested revised regulations to better inform and protect consumers. I concluded by noting new directions in the area of sugar research for future public health policy. PMID:22594751

Self-regulating flow control device

DOEpatents

Humphreys, Duane A.

1984-01-01

A variable, self-regulating valve having a hydraulic loss coefficient proportional to a positive exponential power of the flow rate. The device includes two objects in a flow channel and structure which assures that the distance between the two objects is an increasing function of the flow rate. The range of spacing between the objects is such that the hydraulic resistance of the valve is an increasing function of the distance between the two objects so that the desired hydraulic loss coefficient as a function of flow rate is obtained without variation in the flow area.

Self-regulating valve

DOEpatents

Humphreys, D.A.

1982-07-20

A variable, self-regulating valve having a hydraulic loss coefficient proportional to a positive exponential power of the flow rate. The device includes two objects in a flow channel and structure which assures that the distance between the two objects is an increasing function of the flow rate. The range of spacing between the objects is such that the hydraulic resistance of the valve is an increasing function of the distance between the two objects so that the desired hydraulic loss coefficient as a function of flow rate is obtained without variation in the flow area.

International Conference on Problems Related to the Stratosphere

NASA Technical Reports Server (NTRS)

Huntress, W., Jr.

1977-01-01

The conference focused on four main areas of investigation: laboratory studies and stratospheric chemistry and constituents, sources for and chemical budget of stratospheric halogen compounds, sources for and chemical budget of stratospheric nitrous oxide, and the dynamics of decision making on regulation of potential pollutants of the stratosphere. Abstracts of the scientific sessions of the conference as well as complete transcriptions of the panel discussions on sources for an atmospheric budget of holocarbons and nitrous oxide are included. The political, social and economic issues involving regulation of potential stratospheric pollutants were examined extensively.

Simulation of a Cold Gas Thruster System and Test Data Correlation

NASA Technical Reports Server (NTRS)

Hauser, Daniel M.; Quinn, Frank D.

2012-01-01

During developmental testing of the Ascent Abort 1 (AA-1) cold gas thruster system, unexpected behavior was detected. Upon further review the design as it existed may not have met the requirements. To determine the best approach for modifying the design, the system was modeled with a dynamic fluid analysis tool (EASY5). The system model consisted of the nitrogen storage tank, pressure regulator, thruster valve, nozzle, and the associated interconnecting line lengths. The regulator and thruster valves were modeled using a combination of the fluid and mechanical modules available in EASY5. The simulation results were then compared against actual system test data. The simulation results exhibited behaviors similar to the test results, such as the pressure regulators response to thruster firings. Potential design solutions were investigated using the analytical model parameters, including increasing the volume downstream of the regulator and increasing the orifice area. Both were shown to improve the regulator response.

75 FR 22228 - Regulated Navigation Area; Lake Champlain Bridge Construction Zone, NY and VT

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-28

...-AA11 Regulated Navigation Area; Lake Champlain Bridge Construction Zone, NY and VT AGENCY: Coast Guard... establishing a regulated navigation area around the construction zone of the Lake Champlain Bridge between... on all vessels transiting the navigable waters of Lake Champlain in the vicinity of the bridge...

33 CFR 165.756 - Regulated Navigation Area; Savannah River, Georgia.

Code of Federal Regulations, 2013 CFR

2013-07-01

....756 Regulated Navigation Area; Savannah River, Georgia. (a) Regulated Navigation Area (RNA). The... as a method of operation by which a towing vessel generates towline forces by thrust alone at an... presumed to be heel. Indirect mode means a towing technique defined as a method of operation by which an...

33 CFR 165.756 - Regulated Navigation Area; Savannah River, Georgia.

Code of Federal Regulations, 2012 CFR

2012-07-01

....756 Regulated Navigation Area; Savannah River, Georgia. (a) Regulated Navigation Area (RNA). The... as a method of operation by which a towing vessel generates towline forces by thrust alone at an... presumed to be heel. Indirect mode means a towing technique defined as a method of operation by which an...

33 CFR 165.756 - Regulated Navigation Area; Savannah River, Georgia.

Code of Federal Regulations, 2010 CFR

2010-07-01

....756 Regulated Navigation Area; Savannah River, Georgia. (a) Regulated Navigation Area (RNA). The... as a method of operation by which a towing vessel generates towline forces by thrust alone at an... presumed to be heel. Indirect mode means a towing technique defined as a method of operation by which an...

33 CFR 165.756 - Regulated Navigation Area; Savannah River, Georgia.

Code of Federal Regulations, 2011 CFR

2011-07-01

....756 Regulated Navigation Area; Savannah River, Georgia. (a) Regulated Navigation Area (RNA). The... as a method of operation by which a towing vessel generates towline forces by thrust alone at an... presumed to be heel. Indirect mode means a towing technique defined as a method of operation by which an...

33 CFR 165.756 - Regulated Navigation Area; Savannah River, Georgia.

Code of Federal Regulations, 2014 CFR

2014-07-01

....756 Regulated Navigation Area; Savannah River, Georgia. (a) Regulated Navigation Area (RNA). The... as a method of operation by which a towing vessel generates towline forces by thrust alone at an... presumed to be heel. Indirect mode means a towing technique defined as a method of operation by which an...

miR-9 and miR-140-5p target FoxP2 and are regulated as a function of the social context of singing behavior in zebra finches.

PubMed

Shi, Zhimin; Luo, Guanzheng; Fu, Lijuan; Fang, Zhide; Wang, XiuJie; Li, XiaoChing

2013-10-16

Mutations in the FOXP2 gene cause speech and language impairments, accompanied by structural and functional abnormalities in brain regions underlying speech-related sensory-motor processing, including the striatum and cerebellum. The sequence and expression patterns of FOXP2 are highly conserved among higher vertebrates. In the zebra finch brain, FoxP2 is expressed in Area X, a striatal nucleus required for vocal learning, and reduced FoxP2 expression impairs dendritic development and vocal learning. The FoxP2 gene encodes a transcription factor that controls the expression of many downstream genes. However, how FOXP2 gene expression is regulated is not clearly understood. miRNAs regulate gene expression post-transcriptionally by targeting the 3'-untranslated regions (UTRs) of mRNAs, leading to translational suppression or mRNA degradation. In this study, we identified miR-9 and miR-140-5p as potential regulators of the FoxP2 gene. We show that both miR-9 and miR-140-5p target specific sequences in the FoxP2 3'-UTR and downregulate FoxP2 protein and mRNA expression in vitro. We also show that the expression of miR-9 and miR-140-5p in Area X of the zebra finch brain is regulated during song development in juvenile zebra finches. We further show that in adult zebra finches the expression of miR-9 and miR-140-5p in Area X is regulated as a function of the social context of song behavior in males singing undirected songs. Our findings reveal a post-transcriptional mechanism that regulates FoxP2 expression and suggest that social vocal behavior can influence the basal ganglia circuit controlling vocal learning via a miRNA-FoxP2 gene regulatory network.

miR-9 and miR-140-5p Target FoxP2 and Are Regulated as a Function of the Social Context of Singing Behavior in Zebra Finches

PubMed Central

Shi, Zhimin; Luo, Guanzheng; Fu, Lijuan; Fang, Zhide; Wang, XiuJie

2013-01-01

Mutations in the FOXP2 gene cause speech and language impairments, accompanied by structural and functional abnormalities in brain regions underlying speech-related sensory-motor processing, including the striatum and cerebellum. The sequence and expression patterns of FOXP2 are highly conserved among higher vertebrates. In the zebra finch brain, FoxP2 is expressed in Area X, a striatal nucleus required for vocal learning, and reduced FoxP2 expression impairs dendritic development and vocal learning. The FoxP2 gene encodes a transcription factor that controls the expression of many downstream genes. However, how FOXP2 gene expression is regulated is not clearly understood. miRNAs regulate gene expression post-transcriptionally by targeting the 3′-untranslated regions (UTRs) of mRNAs, leading to translational suppression or mRNA degradation. In this study, we identified miR-9 and miR-140-5p as potential regulators of the FoxP2 gene. We show that both miR-9 and miR-140-5p target specific sequences in the FoxP2 3′-UTR and downregulate FoxP2 protein and mRNA expression in vitro. We also show that the expression of miR-9 and miR-140-5p in Area X of the zebra finch brain is regulated during song development in juvenile zebra finches. We further show that in adult zebra finches the expression of miR-9 and miR-140-5p in Area X is regulated as a function of the social context of song behavior in males singing undirected songs. Our findings reveal a post-transcriptional mechanism that regulates FoxP2 expression and suggest that social vocal behavior can influence the basal ganglia circuit controlling vocal learning via a miRNA-FoxP2 gene regulatory network. PMID:24133256

The utilization and management of plant resources in rural areas of the Limpopo Province, South Africa

PubMed Central

2013-01-01

Background Most rural people in the Limpopo Province depend on plant resources to meet their livelihood needs. However, there is insufficient recorded information regarding their use and management. The current study therefore was carried out in selected villages of the Limpopo Province, to close this knowledge gap. Methods Information was collected from 60 people residing in two villages, using a semi-structured questionnaire, supplemented with field observations. Results A total of 47 wild plant species (95% indigenous and 5% exotics) from 27 families, mostly from the Fabaceae (17%), Anacardiaceae (9%), and Combretaceae (9%) were documented. These species were used primarily for firewood (40%), food (36%) and medicine (29%). Significantly used species included Sclerocarya birrea (85%), Combretum kraussii (35%) and Harpephyllum caffrum (35%). Local traditional rules and regulations including taboos, social beliefs and fines are in place to aid in the management of communal resources. However, a significant number (67%) of participants mentioned that they were not pleased with these rules and regulations. Conclusion The current study concluded that plant resources still play an important role in the surveyed rural areas of the Limpopo Province. Furthermore, for sustainable utilization and long-term conservation of plants in these areas the government should assist communities in the management of their plant resources. PMID:23590903

Post-translational Regulation of Neuronal Nitric Oxide Synthase: Implications for sympatho-excitatory states

PubMed Central

Sharma, Neeru M; Patel, Kaushik P

2017-01-01

Introduction Nitric oxide (NO) synthesized via neuronal nitric oxide synthase (nNOS) plays a significant role in regulation/modulation of autonomic control of circulation. Various pathological states are associated with diminished nNOS expression and blunted autonomic effects of NO in the central nervous system (CNS) including heart failure, hypertension, diabetes mellitus, chronic renal failure etc. Therefore, elucidation of the molecular mechanism/s involved in dysregulation of nNOS is essential to understand the pathogenesis of increased sympathoexcitation in these diseased states. Areas Covered nNOS is a highly regulated enzyme, being regulated at transcriptional and posttranslational levels via protein-protein interactions and modifications viz. phosphorylation, ubiquitination, and sumoylation. The enzyme activity of nNOS also depends on the optimal concentration of substrate, cofactors and association with regulatory proteins. This review focuses on the posttranslational regulation of nNOS in the context of normal and diseased states within the CNS. Expert Opinion Gaining insight into the mechanism/s involved in the regulation of nNOS would provide novel strategies for manipulating nNOS directed therapeutic modalities in the future, including catalytically active dimer stabilization and protein-protein interactions with intracellular protein effectors. Ultimately, this is expected to provide tools to improve autonomic dysregulation in various diseases such as heart failure, hypertension, and diabetes. PMID:27885874

7 CFR 301.75-4 - Quarantined areas.

Code of Federal Regulations, 2010 CFR

2010-01-01

...) Grass, tree, and plant clippings may be moved intrastate from the quarantined area for disposal in a...)(1) of this section, (B) The grass, tree, or plant clippings are completely covered during the... regulated plant and regulated tree, except indoor houseplants and regulated plants and regulated trees at...

MycoKey Round Table Discussions of Future Directions in Research on Chemical Detection Methods, Genetics and Biodiversity of Mycotoxins.

PubMed

Leslie, John F; Lattanzio, Veronica; Audenaert, Kris; Battilani, Paola; Cary, Jeffrey; Chulze, Sofia N; De Saeger, Sarah; Gerardino, Annamaria; Karlovsky, Petr; Liao, Yu-Cai; Maragos, Chris M; Meca, Giuseppe; Medina, Angel; Moretti, Antonio; Munkvold, Gary; Mulè, Giuseppina; Njobeh, Patrick; Pecorelli, Ivan; Perrone, Giancarlo; Pietri, Amedeo; Palazzini, Juan M; Proctor, Robert H; Rahayu, Endang S; Ramírez, Maria L; Samson, Robert; Stroka, Jörg; Sulyok, Michael; Sumarah, Mark; Waalwijk, Cees; Zhang, Qi; Zhang, Hao; Logrieco, Antonio F

2018-03-01

MycoKey, an EU-funded Horizon 2020 project, includes a series of "Roundtable Discussions" to gather information on trending research areas in the field of mycotoxicology. This paper includes summaries of the Roundtable Discussions on Chemical Detection and Monitoring of mycotoxins and on the role of genetics and biodiversity in mycotoxin production. Discussions were managed by using the nominal group discussion technique, which generates numerous ideas and provides a ranking for those identified as the most important. Four questions were posed for each research area, as well as two questions that were common to both discussions. Test kits, usually antibody based, were one major focus of the discussions at the Chemical Detection and Monitoring roundtable because of their many favorable features, e.g., cost, speed and ease of use. The second area of focus for this roundtable was multi-mycotoxin detection protocols and the challenges still to be met to enable these protocols to become methods of choice for regulated mycotoxins. For the genetic and biodiversity group, both the depth and the breadth of trending research areas were notable. For some areas, e.g., microbiome studies, the suggested research questions were primarily of a descriptive nature. In other areas, multiple experimental approaches, e.g., transcriptomics, proteomics, RNAi and gene deletions, are needed to understand the regulation of toxin production and mechanisms underlying successful biological controls. Answers to the research questions will provide starting points for developing acceptable prevention and remediation processes. Forging a partnership between scientists and appropriately-placed communications experts was recognized by both groups as an essential step to communicating risks, while retaining overall confidence in the safety of the food supply and the integrity of the food production chain.

MycoKey Round Table Discussions of Future Directions in Research on Chemical Detection Methods, Genetics and Biodiversity of Mycotoxins

PubMed Central

Lattanzio, Veronica; Cary, Jeffrey; Chulze, Sofia N.; Gerardino, Annamaria; Liao, Yu-Cai; Maragos, Chris M.; Meca, Giuseppe; Moretti, Antonio; Munkvold, Gary; Mulè, Giuseppina; Njobeh, Patrick; Pecorelli, Ivan; Pietri, Amedeo; Proctor, Robert H.; Rahayu, Endang S.; Ramírez, Maria L.; Samson, Robert; Stroka, Jörg; Sumarah, Mark; Zhang, Qi; Zhang, Hao; Logrieco, Antonio F.

2018-01-01

MycoKey, an EU-funded Horizon 2020 project, includes a series of “Roundtable Discussions” to gather information on trending research areas in the field of mycotoxicology. This paper includes summaries of the Roundtable Discussions on Chemical Detection and Monitoring of mycotoxins and on the role of genetics and biodiversity in mycotoxin production. Discussions were managed by using the nominal group discussion technique, which generates numerous ideas and provides a ranking for those identified as the most important. Four questions were posed for each research area, as well as two questions that were common to both discussions. Test kits, usually antibody based, were one major focus of the discussions at the Chemical Detection and Monitoring roundtable because of their many favorable features, e.g., cost, speed and ease of use. The second area of focus for this roundtable was multi-mycotoxin detection protocols and the challenges still to be met to enable these protocols to become methods of choice for regulated mycotoxins. For the genetic and biodiversity group, both the depth and the breadth of trending research areas were notable. For some areas, e.g., microbiome studies, the suggested research questions were primarily of a descriptive nature. In other areas, multiple experimental approaches, e.g., transcriptomics, proteomics, RNAi and gene deletions, are needed to understand the regulation of toxin production and mechanisms underlying successful biological controls. Answers to the research questions will provide starting points for developing acceptable prevention and remediation processes. Forging a partnership between scientists and appropriately-placed communications experts was recognized by both groups as an essential step to communicating risks, while retaining overall confidence in the safety of the food supply and the integrity of the food production chain. PMID:29494529

Physiological factors that regulate skin pigmentation

PubMed Central

Yamaguchi, Yuji; Hearing, Vincent J.

2009-01-01

More than 150 genes have been identified that affect skin color either directly or indirectly, and we review current understanding of physiological factors that regulate skin pigmentation. We focus on melanosome biogenesis, transport and transfer, melanogenic regulators in melanocytes and factors derived from keratinocytes, fibroblasts, endothelial cells, hormones, inflammatory cells and nerves. Enzymatic components of melanosomes include tyrosinase, tyrosinase-related protein 1 and dopachrome tautomerase, which depend on the functions of OA1, P, MATP, ATP7A and BLOC-1 to synthesize eumelanins and pheomelanins. The main structural component of melanosomes is Pmel17/gp100/Silv, whose sorting involves adaptor protein 1A (AP1A), AP1B, AP2 and spectrin, as well as a chaperone-like component, MART-1. During their maturation, melanosomes move from the perinuclear area toward the plasma membrane. Microtubules, dynein, kinesin, actin filaments, Rab27a, melanophilin, myosin Va and Slp2-a are involved in melanosome transport. Foxn1 and p53 up-regulate skin pigmentation via bFGF and POMC derivatives including α-MSH and ACTH, respectively. Other critical factors that affect skin pigmentation include MC1R, CREB, ASP, MITF, PAX3, SOX9/10, LEF-1/TCF, PAR-2, DKK1, SCF, HGF, GM-CSF, endothelin-1, prostaglandins, leukotrienes, thromboxanes, neurotrophins and neuropeptides. UV radiation up-regulates most factors that increase melanogenesis. Further studies will elucidate the currently unknown functions of many other pigment genes/proteins. PMID:19449448

76 FR 55653 - Notice of Intent To Prepare an Environmental Impact Statement/Overseas Environmental Impact...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-08

...Pursuant to section 102(2)(c) of the National Environmental Policy Act of 1969, as implemented by the Council on Environmental Quality Regulations (40 Code of Federal Regulations parts 1500-1508), and Executive Order 12114, the Department of the Navy (DoN) announces its intent to prepare an Environmental Impact Statement (EIS)/Overseas Environmental Impact Statement (OEIS) to evaluate the potential environmental effects associated with maintaining military readiness training and research, development, testing, and evaluation (hereafter referred to as ``training and testing'') activities conducted in the Mariana Islands Training and Testing (MITT) EIS/OEIS Study Area. The MITT Study Area includes the existing Mariana Islands Range Complex (MIRC), additional areas on the high seas, and a general transit corridor between Hawaii to MITT where training and testing activities may occur. The MIRC is the only major Navy range complex in the Study Area. The DoN is preparing this EIS/OEIS to renew current regulatory permits and authorizations, address current training and testing not covered under existing permits and authorizations, and to obtain those permits and authorizations necessary to support force structure changes and emerging and future training and testing requirements including those associated with new platforms and weapons systems within the MITT Study Area, starting in 2015, thereby ensuring critical Department of Defense (DoD) requirements are met. The DoN will invite the National Marine Fisheries Service, United States (U.S.) Fish and Wildlife Service (Pacific Islands Fish and Wildlife Office), and U.S. Air Force, to be cooperating agencies in preparation of the EIS/OEIS.

33 CFR 165.500 - Safety/Security Zones; Chesapeake Bay, Maryland.

Code of Federal Regulations, 2010 CFR

2010-07-01

... designated representative. (3) Persons desiring to transit the area of the security zone may contact the COTP... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS Specific Regulated Navigation Areas and Limited Access Areas Fifth Coast Guard District § 165.500...

33 CFR 165.1108 - Security Zones; Cruise Ships, Port of San Diego, California.

Code of Federal Regulations, 2010 CFR

2010-07-01

... to transit the area of the security zones may contact the Captain of the Port at telephone number..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS Specific Regulated Navigation Areas and Limited Access Areas Eleventh Coast Guard District...

Volitional regulation of brain responses to food stimuli in overweight and obese subjects: A real-time fMRI feedback study.

PubMed

Spetter, Maartje S; Malekshahi, Rahim; Birbaumer, Niels; Lührs, Michael; van der Veer, Albert H; Scheffler, Klaus; Spuckti, Sophia; Preissl, Hubert; Veit, Ralf; Hallschmid, Manfred

2017-05-01

Obese subjects who achieve weight loss show increased functional connectivity between dorsolateral prefrontal cortex (dlPFC) and ventromedial prefrontal cortex (vmPFC), key areas of executive control and reward processing. We investigated the potential of real-time functional magnetic resonance imaging (rt-fMRI) neurofeedback training to achieve healthier food choices by enhancing self-control of the interplay between these brain areas. We trained eight male individuals with overweight or obesity (age: 31.8 ± 4.4 years, BMI: 29.4 ± 1.4 kg/m 2 ) to up-regulate functional connectivity between the dlPFC and the vmPFC by means of a four-day rt-fMRI neurofeedback protocol including, on each day, three training runs comprised of six up-regulation and six passive viewing trials. During the up-regulation runs of the four training days, participants successfully learned to increase functional connectivity between dlPFC and vmPFC. In addition, a trend towards less high-calorie food choices emerged from before to after training, which however was associated with a trend towards increased covertly assessed snack intake. Findings of this proof-of-concept study indicate that overweight and obese participants can increase functional connectivity between brain areas that orchestrate the top-down control of appetite for high-calorie foods. Neurofeedback training might therefore be a useful tool in achieving and maintaining weight loss. Copyright © 2017 Elsevier Ltd. All rights reserved.

Affective brain areas and sleep disordered breathing

PubMed Central

Harper, Ronald M.; Kumar, Rajesh; Macey, Paul M.; Woo, Mary A.; Ogren, Jennifer A.

2014-01-01

The neural damage accompanying the hypoxia, reduced perfusion, and other consequences of sleep-disordered breathing found in obstructive sleep apnea, heart failure (HF), and congenital central hypoventilation syndrome (CCHS), appears in areas that serve multiple functions, including emotional drives to breathe, and involve systems that serve affective, cardiovascular, and breathing roles. The damage, assessed with structural magnetic resonance imaging (MRI) procedures, shows tissue loss or water content and diffusion changes indicative of injury, and impaired axonal integrity between structures; damage is preferentially unilateral. Functional MRI responses in affected areas also are time- or amplitude- distorted to ventilatory or autonomic challenges. Among the structures injured are the insular, cingulate, and ventral medial prefrontal cortices, as well as cerebellar deep nuclei and cortex, anterior hypothalamus, raphé, ventrolateral medulla, basal ganglia and, in CCHS, the locus coeruleus. Raphé and locus coeruleus injury may modify serotonergic and adrenergic modulation of upper airway and arousal characteristics. Since both axons and gray matter show injury, the consequences to function, especially to autonomic, cognitive, and mood regulation, are major. Several affected rostral sites, including the insular and cingulate cortices and hippocampus, mediate aspects of dyspnea, especially in CCHS, while others, including the anterior cingulate and thalamus, participate in initiation of inspiration after central breathing pauses, and the medullary injury can impair baroreflex and breathing control. The ancillary injury associated with sleep-disordered breathing to central structures can elicit multiple other distortions in cardiovascular, cognitive, and emotional functions in addition to effects on breathing regulation. PMID:24746053

33 CFR 165.1323 - Regulated Navigation Area: Willamette River Portland, Oregon Captain of the Port Zone.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Regulated Navigation Area: Willamette River Portland, Oregon Captain of the Port Zone. 165.1323 Section 165.1323 Navigation and..., Oregon Captain of the Port Zone. (a) Location. The following is a regulated navigation area (RNA): All...

33 CFR 165.1322 - Regulated Navigation Area: Willamette River Portland, Oregon Captain of the Port Zone.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Regulated Navigation Area: Willamette River Portland, Oregon Captain of the Port Zone. 165.1322 Section 165.1322 Navigation and..., Oregon Captain of the Port Zone. (a) Location. The following is a regulated navigation area (RNA): All...

7 CFR 301.85-2 - Authorization to designate, and terminate designation of, regulated areas and suppressive or...

Code of Federal Regulations, 2014 CFR

2014-01-01

... DOMESTIC QUARANTINE NOTICES Golden Nematode Quarantine and Regulations § 301.85-2 Authorization to... nematode has been found or in which there is reason to believe that golden nematode is present, or which it... nematode. (b) Temporary designation of regulated areas and suppressive or generally infested areas. The...

7 CFR 301.85-2 - Authorization to designate, and terminate designation of, regulated areas and suppressive or...

Code of Federal Regulations, 2012 CFR

2012-01-01

... DOMESTIC QUARANTINE NOTICES Golden Nematode Quarantine and Regulations § 301.85-2 Authorization to... nematode has been found or in which there is reason to believe that golden nematode is present, or which it... nematode. (b) Temporary designation of regulated areas and suppressive or generally infested areas. The...

7 CFR 301.85-2 - Authorization to designate, and terminate designation of, regulated areas and suppressive or...

Code of Federal Regulations, 2013 CFR

2013-01-01

... DOMESTIC QUARANTINE NOTICES Golden Nematode Quarantine and Regulations § 301.85-2 Authorization to... nematode has been found or in which there is reason to believe that golden nematode is present, or which it... nematode. (b) Temporary designation of regulated areas and suppressive or generally infested areas. The...

7 CFR 301.85-2 - Authorization to designate, and terminate designation of, regulated areas and suppressive or...

Code of Federal Regulations, 2011 CFR

2011-01-01

... DOMESTIC QUARANTINE NOTICES Golden Nematode Quarantine and Regulations § 301.85-2 Authorization to... nematode has been found or in which there is reason to believe that golden nematode is present, or which it... nematode. (b) Temporary designation of regulated areas and suppressive or generally infested areas. The...

7 CFR 301.85-2 - Authorization to designate, and terminate designation of, regulated areas and suppressive or...

Code of Federal Regulations, 2010 CFR

2010-01-01

... DOMESTIC QUARANTINE NOTICES Golden Nematode Quarantine and Regulations § 301.85-2 Authorization to... nematode has been found or in which there is reason to believe that golden nematode is present, or which it... nematode. (b) Temporary designation of regulated areas and suppressive or generally infested areas. The...

77 FR 73916 - Regulated Navigation Area; S99 Alford Street Bridge Rehabilitation Project, Mystic River, MA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-12

...-AA11 Regulated Navigation Area; S99 Alford Street Bridge Rehabilitation Project, Mystic River, MA... against hazardous conditions created by repair work on the S99 Alford Street Bridge across the Mystic... Coast Guard to establish a regulated navigation area in connection with the S99 Alford Street Bridge...

33 CFR 165.921 - Regulated Navigation Area; Reporting Requirements for Barges Loaded with Certain Dangerous...

Code of Federal Regulations, 2013 CFR

2013-07-01

... RNA must report the information required by this section as set out in table 165.921(g) to this...) Regulated Navigation Area. The following waters are a regulated navigation area (RNA): the Illinois Waterway... RNA. This section does not apply to towing vessel operators responsible for barges not carrying CDC...

33 CFR 165.921 - Regulated Navigation Area; Reporting Requirements for Barges Loaded with Certain Dangerous...

Code of Federal Regulations, 2010 CFR

2010-07-01

... RNA must report the information required by this section as set out in table 165.921(g) to this...) Regulated Navigation Area. The following waters are a regulated navigation area (RNA): the Illinois Waterway... RNA. This section does not apply to towing vessel operators responsible for barges not carrying CDC...

33 CFR 165.921 - Regulated Navigation Area; Reporting Requirements for Barges Loaded with Certain Dangerous...

Code of Federal Regulations, 2011 CFR

2011-07-01

... RNA must report the information required by this section as set out in table 165.921(g) to this...) Regulated Navigation Area. The following waters are a regulated navigation area (RNA): the Illinois Waterway... RNA. This section does not apply to towing vessel operators responsible for barges not carrying CDC...

33 CFR 165.921 - Regulated Navigation Area; Reporting Requirements for Barges Loaded with Certain Dangerous...

Code of Federal Regulations, 2014 CFR

2014-07-01

... RNA must report the information required by this section as set out in table 165.921(g) to this...) Regulated Navigation Area. The following waters are a regulated navigation area (RNA): the Illinois Waterway... RNA. This section does not apply to towing vessel operators responsible for barges not carrying CDC...

33 CFR 165.921 - Regulated Navigation Area; Reporting Requirements for Barges Loaded with Certain Dangerous...

Code of Federal Regulations, 2012 CFR

2012-07-01

... RNA must report the information required by this section as set out in table 165.921(g) to this...) Regulated Navigation Area. The following waters are a regulated navigation area (RNA): the Illinois Waterway... RNA. This section does not apply to towing vessel operators responsible for barges not carrying CDC...

Corrective Action Decision Document/Corrective Action Plan for the 92-Acre Area and Corrective Action Unit 111: Area 5 WMD Retired Mixed Waste Pits, Nevada National Security Site, Nevada

DOE Office of Scientific and Technical Information (OSTI.GOV)

NSTec Environmental Restoration

This Corrective Action Decision Document/Corrective Action Plan (CADD/CAP) has been prepared for the 92-Acre Area, the southeast quadrant of the Radioactive Waste Management Site, located in Area 5 of the Nevada National Security Site (NNSS). The 92-Acre Area includes Corrective Action Unit (CAU) 111, 'Area 5 WMD Retired Mixed Waste Pits.' Data Quality Objectives (DQOs) were developed for the 92-Acre Area, which includes CAU 111. The result of the DQO process was that the 92-Acre Area is sufficiently characterized to provide the input data necessary to evaluate corrective action alternatives (CAAs) without the collection of additional data. The DQOs aremore » included as Appendix A of this document. This CADD/CAP identifies and provides the rationale for the recommended CAA for the 92-Acre Area, provides the plan for implementing the CAA, and details the post-closure plan. When approved, this CADD/CAP will supersede the existing Pit 3 (P03) Closure Plan, which was developed in accordance with Title 40 Code of Federal Regulations (CFR) Part 265, 'Interim Status Standards for Owners and Operators of Hazardous Waste Treatment, Storage, and Disposal Facilities.' This document will also serve as the Closure Plan and the Post-Closure Plan, which are required by 40 CFR 265, for the 92-Acre Area. After closure activities are complete, a request for the modification of the Resource Conservation and Recovery Act Permit that governs waste management activities at the NNSS will be submitted to the Nevada Division of Environmental Protection to incorporate the requirements for post-closure monitoring. Four CAAs, ranging from No Further Action to Clean Closure, were evaluated for the 92-Acre Area. The CAAs were evaluated on technical merit focusing on performance, reliability, feasibility, safety, and cost. Based on the evaluation of the data used to develop the conceptual site model; a review of past, current, and future operations at the site; and the detailed and comparative analysis of the potential CAAs, Closure in Place with Administrative Controls is the preferred CAA for the 92-Acre Area. Closure activities will include the following: (1) Constructing an engineered evapotranspiration cover over the 92-Acre Area; (2) Installing use restriction (UR) warning signs, concrete monuments, and subsidence survey monuments; (3) Establishing vegetation on the cover; (4) Implementing a UR; and (5) Implementing post-closure inspections and monitoring. The Closure in Place with Administrative Controls alternative meets all requirements for the technical components evaluated, fulfills all applicable federal and state regulations for closure of the site, and will minimize potential future exposure pathways to the buried waste at the site.« less

24 CFR 248.173 - Resident homeownership program.

Code of Federal Regulations, 2010 CFR

2010-04-01

... specified in paragraph (i) of this section, and any restrictions on homeowners' equity, over and above those...); the Age Discrimination Act of 1975 (42 U.S.C. 6101-6107); and all regulations issued pursuant to these... moderate income tenants (including families and persons whose incomes are 95 percent or more of area median...

78 FR 57368 - Taking and Importing Marine Mammals: Taking Marine Mammals Incidental to Navy Operations of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-18

... certain subsistence uses. In addition, we must prescribe regulations that include permissible methods of... the Navy to convene a Scientific Advisory Group (SAG) to analyze different types of monitoring and... following areas: Atlantic Ocean: Southeast Shoal-Grand Banks, Canada; Grand Manan Basin Right Whale...

76 FR 56272 - Pilot Project on NAFTA Trucking Provisions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-12

... controls. A list of acute and critical regulations is included in 49 CFR part 385, Appendix B, Section VII... areas called ``factors.'' The regulatory factors are intended to evaluate the adequacy of a carrier's management controls. L. Passed Phase 1, Factor 1: A ``yes'' in this column indicates the carrier has...

78 FR 46922 - Atlantic Coastal Fisheries Cooperative Management Act Provisions; General Provisions for Domestic...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-02

... Federal lobster regulations in order to help determine the abundance and distribution of juvenile American lobsters at the Massachusetts and Rhode Island offshore wind farm area. The research is being conducted by... methods: Email: [email protected] . Include in the subject line ``Comments on CFRF Lobster EFP.'' Mail...

Faculty Handbook, 75-76. St. Cloud State University.

ERIC Educational Resources Information Center

Saint Cloud State Coll., Minn.

General procedures, policies, and services of the university are outlined in the 1975 edition of the handbook. More detailed information in some areas may be found in other university publications, and a complete set of State University System Rules and Regulations is not included. This handbook is organized into the following sections: university…

36 CFR 1.2 - Applicability and scope.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Applicability and scope. 1.2... PROVISIONS § 1.2 Applicability and scope. (a) The regulations contained in this chapter apply to all persons..., including navigable waters and areas within their ordinary reach (up to the mean high water line in places...

36 CFR 1.2 - Applicability and scope.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Applicability and scope. 1.2... PROVISIONS § 1.2 Applicability and scope. (a) The regulations contained in this chapter apply to all persons..., including navigable waters and areas within their ordinary reach (up to the mean high water line in places...

78 FR 14673 - Special Regulation; Areas of the National Park System, National Capital Region, Demonstrations...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-07

... the change, noting that it would encourage, among other things, greater transparency and consistency... or denied the right of assembly provided that all permit conditions are met''); NPS Director's Order... was vague and may not include a visitor who merely had ``a strange haircut'' or wore ``a controversial...

50 CFR 32.32 - Illinois.

Code of Federal Regulations, 2014 CFR

2014-10-01

... hunter(s) moving through an area with the intent of displacing one or more deer in the direction of... nontoxic shot shells while in the field, including shot shells used for hunting wild turkey (see § 32.2(k... regulations subject to the following conditions: 1. You may only possess approved nontoxic shot while hunting...

Rules for the Provision of Special Education to Special Education Students. Chapter 392-172 WAC.

ERIC Educational Resources Information Center

Washington Office of the State Superintendent of Public Instruction, Olympia.

This handbook provides state legal regulations for Washington State special education services and programs for students with disabilities. It includes requirements that address the following areas: (1) general authority and purpose of the requirements; (2) students' rights; (3) general definitions; (4) child find; (5) evaluation procedures; (6)…

Control Networks and Neuromodulators of Early Development

ERIC Educational Resources Information Center

Posner, Michael I.; Rothbart, Mary K.; Sheese, Brad E.; Voelker, Pascale

2012-01-01

In adults, most cognitive and emotional self-regulation is carried out by a network of brain regions, including the anterior cingulate, insula, and areas of the basal ganglia, related to executive attention. We propose that during infancy, control systems depend primarily upon a brain network involved in orienting to sensory events that includes…

Semiochemicals in pest management: development, regulation and applications. Subtitle: Delivering on the promise of pheromones

USDA-ARS?s Scientific Manuscript database

In this special issue, we present a total of 20 review articles and original research papers in semiochemical applications from not only insects, also in some vertebrates. We have covered many areas of using chemical ecology tools for practical applications from all four continents, which include ph...

33 CFR 165.753 - Regulated navigation area; Tampa Bay, Florida.

Code of Federal Regulations, 2011 CFR

2011-07-01

... (RNA): All the navigable waters of Tampa Bay, Hillsborough Bay and Old Tampa Bay, including all... nature of any hazardous conditions as defined by 33 CFR 160.203. (d) Nothing in this section shall... Inland Navigation Rules, as applicable, or relieve the Master or person in charge of the vessel of...

33 CFR 165.753 - Regulated navigation area; Tampa Bay, Florida.

Code of Federal Regulations, 2013 CFR

2013-07-01

... (RNA): All the navigable waters of Tampa Bay, Hillsborough Bay and Old Tampa Bay, including all... nature of any hazardous conditions as defined by 33 CFR 160.203. (d) Nothing in this section shall... Inland Navigation Rules, as applicable, or relieve the Master or person in charge of the vessel of...

33 CFR 165.753 - Regulated navigation area; Tampa Bay, Florida.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (RNA): All the navigable waters of Tampa Bay, Hillsborough Bay and Old Tampa Bay, including all... nature of any hazardous conditions as defined by 33 CFR 160.203. (d) Nothing in this section shall... Inland Navigation Rules, as applicable, or relieve the Master or person in charge of the vessel of...

33 CFR 165.753 - Regulated navigation area; Tampa Bay, Florida.

Code of Federal Regulations, 2012 CFR

2012-07-01

... (RNA): All the navigable waters of Tampa Bay, Hillsborough Bay and Old Tampa Bay, including all... nature of any hazardous conditions as defined by 33 CFR 160.203. (d) Nothing in this section shall... Inland Navigation Rules, as applicable, or relieve the Master or person in charge of the vessel of...

33 CFR 165.753 - Regulated navigation area; Tampa Bay, Florida.

Code of Federal Regulations, 2014 CFR

2014-07-01

... (RNA): All the navigable waters of Tampa Bay, Hillsborough Bay and Old Tampa Bay, including all... nature of any hazardous conditions as defined by 33 CFR 160.203. (d) Nothing in this section shall... Inland Navigation Rules, as applicable, or relieve the Master or person in charge of the vessel of...

A review of adipocyte lineage cells and dermal papilla cells in hair follicle regeneration

PubMed Central

Zhang, Peipei; Kling, Russell E; Ravuri, Sudheer K; Kokai, Lauren E; Rubin, J Peter; Chai, Jia-ke

2014-01-01

Alopecia is an exceedingly prevalent problem effecting men and women of all ages. The standard of care for alopecia involves either transplanting existing hair follicles to bald areas or attempting to stimulate existing follicles with topical and/or oral medication. Yet, these treatment options are fraught with problems of cost, side effects, and, most importantly, inadequate long-term hair coverage. Innovative cell-based therapies have focused on the dermal papilla cell as a way to grow new hair in previously bald areas. However, despite this attention, many obstacles exist, including retention of dermal papilla inducing ability and maintenance of dermal papilla productivity after several passages of culture. The use of adipocyte lineage cells, including adipose-derived stem cells, has shown promise as a cell-based solution to regulate hair regeneration and may help in maintaining or increasing dermal papilla cells inducing hair ability. In this review, we highlight recent advances in the understanding of the cellular contribution and regulation of dermal papilla cells and summarize adipocyte lineage cells in hair regeneration. PMID:25383178

Broiler weight estimation based on machine vision and artificial neural network.

PubMed

Amraei, S; Abdanan Mehdizadeh, S; Salari, S

2017-04-01

1. Machine vision and artificial neural network (ANN) procedures were used to estimate live body weight of broiler chickens in 30 1-d-old broiler chickens reared for 42 d. 2. Imaging was performed two times daily. To localise chickens within the pen, an ellipse fitting algorithm was used and the chickens' head and tail removed using the Chan-Vese method. 3. The correlations between the body weight and 6 physical extracted features indicated that there were strong correlations between body weight and the 5 features including area, perimeter, convex area, major and minor axis length. 5. According to statistical analysis there was no significant difference between morning and afternoon data over 42 d. 6. In an attempt to improve the accuracy of live weight approximation different ANN techniques, including Bayesian regulation, Levenberg-Marquardt, Scaled conjugate gradient and gradient descent were used. Bayesian regulation with R 2 value of 0.98 was the best network for prediction of broiler weight. 7. The accuracy of the machine vision technique was examined and most errors were less than 50 g.

Microbiota regulation of the Mammalian gut-brain axis.

PubMed

Burokas, Aurelijus; Moloney, Rachel D; Dinan, Timothy G; Cryan, John F

2015-01-01

The realization that the microbiota-gut-brain axis plays a critical role in health and disease has emerged over the past decade. The brain-gut axis is a bidirectional communication system between the central nervous system (CNS) and the gastrointestinal tract. Regulation of the microbiota-brain-gut axis is essential for maintaining homeostasis, including that of the CNS. The routes of this communication are not fully elucidated but include neural, humoral, immune, and metabolic pathways. A number of approaches have been used to interrogate this axis including the use of germ-free animals, probiotic agents, antibiotics, or animals exposed to pathogenic bacterial infections. Together, it is clear that the gut microbiota can be a key regulator of mood, cognition, pain, and obesity. Understanding microbiota-brain interactions is an exciting area of research which may contribute new insights into individual variations in cognition, personality, mood, sleep, and eating behavior, and how they contribute to a range of neuropsychiatric diseases ranging from affective disorders to autism and schizophrenia. Finally, the concept of psychobiotics, bacterial-based interventions with mental health benefit, is also emerging. Copyright © 2015 Elsevier Inc. All rights reserved.

Monitoring and regulation of learning in medical education: the need for predictive cues.

PubMed

de Bruin, Anique B H; Dunlosky, John; Cavalcanti, Rodrigo B

2017-06-01

Being able to accurately monitor learning activities is a key element in self-regulated learning in all settings, including medical schools. Yet students' ability to monitor their progress is often limited, leading to inefficient use of study time. Interventions that improve the accuracy of students' monitoring can optimise self-regulated learning, leading to higher achievement. This paper reviews findings from cognitive psychology and explores potential applications in medical education, as well as areas for future research. Effective monitoring depends on students' ability to generate information ('cues') that accurately reflects their knowledge and skills. The ability of these 'cues' to predict achievement is referred to as 'cue diagnosticity'. Interventions that improve the ability of students to elicit predictive cues typically fall into two categories: (i) self-generation of cues and (ii) generation of cues that is delayed after self-study. Providing feedback and support is useful when cues are predictive but may be too complex to be readily used. Limited evidence exists about interventions to improve the accuracy of self-monitoring among medical students or trainees. Developing interventions that foster use of predictive cues can enhance the accuracy of self-monitoring, thereby improving self-study and clinical reasoning. First, insight should be gained into the characteristics of predictive cues used by medical students and trainees. Next, predictive cue prompts should be designed and tested to improve monitoring and regulation of learning. Finally, the use of predictive cues should be explored in relation to teaching and learning clinical reasoning. Improving self-regulated learning is important to help medical students and trainees efficiently acquire knowledge and skills necessary for clinical practice. Interventions that help students generate and use predictive cues hold the promise of improved self-regulated learning and achievement. This framework is applicable to learning in several areas, including the development of clinical reasoning. © 2017 The Authors Medical Education published by Association for the Study of Medical Education and John Wiley & Sons Ltd.

Approaches to standardization of atmospheric pollution undergoing long-range and transboundary transport.

PubMed

Izrael, Y A; Nazarov, I M; Ryaboshapko, A G

1982-12-01

The authors consider some possible ways of regulating three types of atmospheric emission of pollutants: - emission of substances causing pollution of the natural environment on the global scale (global pollutants); - emission of substances causing pollution on a regional scale, most often including territories of several countries (international pollutants); - emission of substances causing negative effects in a relatively limited region, for example within border area of two adjoining countries. Substances (gaseous, as a rule) of a long life-time in the atmosphere that can contaminate natural media on a global scale irrespective of the place of emission refer to the first class of pollutants that are subject to emission regulation at an international level and to quota establishement for individual countries. They are carbon dioxide, freon, krypton-85.Various approaches to determining permissible emission and to quota establishing are discussed in the paper.The second group includes substances of a limited, yet rather long, life-time whose emission intensity makes a notable contribution to environmental pollution of a large region including territories of several countries. Here it is needed to regulate internationally not the atmospheric emission as it is but pollutant transport over national boundaries (sulphur and nitrogen oxides, pesticides, heavy metals).The third group includes substances of relatively short time of life producing local effects. Emission regulation in such cases should be based upon bilateral agreements with due account of countries' mutual interests.

7 CFR 916.4 - Production area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Production area. 916.4 Section 916.4 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Regulating Handling Definitions § 916.4 Production area. Production area means the State of California. ...

7 CFR 922.4 - Production area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Production area. 922.4 Section 922.4 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... IN WASHINGTON Order Regulating Handling Definitions § 922.4 Production area. Production area means...

7 CFR 923.4 - Production area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Production area. 923.4 Section 923.4 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... COUNTIES IN WASHINGTON Order Regulating Handling Definitions § 923.4 Production area. Production area means...

7 CFR 946.4 - Production area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Production area. 946.4 Section 946.4 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Order Regulating Handling Definitions § 946.4 Production area. Production area means all territory...

Salience network integrity predicts default mode network function after traumatic brain injury

PubMed Central

Bonnelle, Valerie; Ham, Timothy E.; Leech, Robert; Kinnunen, Kirsi M.; Mehta, Mitul A.; Greenwood, Richard J.; Sharp, David J.

2012-01-01

Efficient behavior involves the coordinated activity of large-scale brain networks, but the way in which these networks interact is uncertain. One theory is that the salience network (SN)—which includes the anterior cingulate cortex, presupplementary motor area, and anterior insulae—regulates dynamic changes in other networks. If this is the case, then damage to the structural connectivity of the SN should disrupt the regulation of associated networks. To investigate this hypothesis, we studied a group of 57 patients with cognitive impairments following traumatic brain injury (TBI) and 25 control subjects using the stop-signal task. The pattern of brain activity associated with stop-signal task performance was studied by using functional MRI, and the structural integrity of network connections was quantified by using diffusion tensor imaging. Efficient inhibitory control was associated with rapid deactivation within parts of the default mode network (DMN), including the precuneus and posterior cingulate cortex. TBI patients showed a failure of DMN deactivation, which was associated with an impairment of inhibitory control. TBI frequently results in traumatic axonal injury, which can disconnect brain networks by damaging white matter tracts. The abnormality of DMN function was specifically predicted by the amount of white matter damage in the SN tract connecting the right anterior insulae to the presupplementary motor area and dorsal anterior cingulate cortex. The results provide evidence that structural integrity of the SN is necessary for the efficient regulation of activity in the DMN, and that a failure of this regulation leads to inefficient cognitive control. PMID:22393019

European experience of regulating distance selling of medicines for Ukraine.

PubMed

Pashkov, Vitalii; Hrekov, Yevhen; Hrekova, Maryna

Some countries have already tried and tested mechanisms of regulating distance sales as form of distribution of medicines that have been used more or less effectively for a fairly long time. Herewith, so far, the approach of the competent authorities of some countries including Ukraine can be called prevailing in quantitative terms under which the official prohibition on distance sales of medicines is set. The aim of this study is a detailed examination of the nature of the prohibition of the medicines distance selling in Ukraine, namely the an analysis of advantages and disadvantages of this form of distribution of medicines and identification of appropriate ways for gradual repeal of the prohibition in terms of regulatory reform in Ukraine in the sphere of circulation of medicines due to the process of adaptation of statutory regulation in this area to the EU legislation. This study is based on Ukrainian regulation acts, Council Directives 97/7/EC, 2000/31/EC, 2001/83/EC, scientific works and opinions of progressiveminded people in this sphere. Such methods as dialectical, comparative, analytic, synthetic and comprehensive have been used in the article. Reception of the described experience of regulation in EU will allow a further review of the principles of regulation in Ukraine in the sphere of medicines with a shift in the main emphasis in the direction of ensuring adequate consumer rights in this area and preventing the risks of patients' and public health.

State regulation and the hazards of milk, 1900-1939.

PubMed

Phillips, J; French, M

1999-12-01

This examination of milk safety before the Second World War focuses on the manner in which government regulation was shaped by the agricultural lobby, acting through the Ministry of Agriculture. Dairy farmers used their market strength to resist the introduction of many regulations which were regarded as desirable and even essential from a public health perspective. These included compulsory pasteurization, favoured by the Ministry of Health and the BMA, but successfully resisted by farmers in the 1930s on commercial grounds and so not actually realized until 1949. This episode crystallized the three related conflicts of interest--between rural and urban areas, the needs of agriculture and public health, and the Ministries of Agriculture and Health--which restricted the expansion of state regulation, ensuring that milk still remained a potentially hazardous and occasionally lethal commodity in the late 1930s.

33 CFR 165.1101 - Security Zone: San Diego Bay, CA.

Code of Federal Regulations, 2010 CFR

2010-07-01

... to transit the area of the security zone may contact the Captain of the Port at telephone number 619... (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS Specific Regulated Navigation Areas and Limited Access Areas Eleventh Coast Guard District § 165.1101 Security Zone: San Diego...

33 CFR 165.1156 - Safety Zone; Offshore Marine Terminal, El Segundo, CA.

Code of Federal Regulations, 2010 CFR

2010-07-01

... area of the safety zone may contact the Captain of the Port at telephone number 1-800-221-8724 or on... OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS Specific Regulated Navigation Areas and Limited Access Areas Eleventh Coast Guard District...

33 CFR 165.776 - Security Zone; Coast Guard Base San Juan, San Juan Harbor, Puerto Rico

Code of Federal Regulations, 2010 CFR

2010-07-01

... GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS Specific Regulated Navigation Areas and Limited Access Areas Seventh Coast...) Location. The following area is a security zone: All waters from surface to bottom, encompassed by an...

36 CFR 3.17 - What regulations apply to swimming areas and beaches?

Code of Federal Regulations, 2010 CFR

2010-07-01

... swimming areas and beaches? 3.17 Section 3.17 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR BOATING AND WATER USE ACTIVITIES § 3.17 What regulations apply to swimming areas and beaches? (a) The superintendent may designate areas as swimming areas or swimming beaches in...

75 FR 8486 - Regulated Navigation Area; Hudson River south of the Troy Locks, New York

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-25

...-AA11 Regulated Navigation Area; Hudson River south of the Troy Locks, New York AGENCY: Coast Guard, DHS... area on the navigable waters of the Hudson River south of the Troy Locks. This regulated navigation... Hudson River south of the Troy locks when ice conditions are 8 inches or greater unless authorized by the...

33 CFR 165.122 - Regulated Navigation Area: Navigable waters within Narragansett Bay and the Providence River...

Code of Federal Regulations, 2010 CFR

2010-07-01

... navigation area (RNA). The Regulated Navigation Area (RNA) encompasses all of the navigable waters of...) Regulations. (1) All commercial vessels must: (i) Maintain a minimum 10% of the vessel's draft as an under... commercial vessel traffic in all locations within this RNA shall keep out of the way of the oncoming deep...

33 CFR 165.122 - Regulated Navigation Area: Navigable waters within Narragansett Bay and the Providence River...

Code of Federal Regulations, 2013 CFR

2013-07-01

... navigation area (RNA). The Regulated Navigation Area (RNA) encompasses all of the navigable waters of...) Regulations. (1) All commercial vessels must: (i) Maintain a minimum 10% of the vessel's draft as an under... commercial vessel traffic in all locations within this RNA shall keep out of the way of the oncoming deep...

33 CFR 165.122 - Regulated Navigation Area: Navigable waters within Narragansett Bay and the Providence River...

Code of Federal Regulations, 2014 CFR

2014-07-01

... navigation area (RNA). The Regulated Navigation Area (RNA) encompasses all of the navigable waters of...) Regulations. (1) All commercial vessels must: (i) Maintain a minimum 10% of the vessel's draft as an under... commercial vessel traffic in all locations within this RNA shall keep out of the way of the oncoming deep...

33 CFR 165.122 - Regulated Navigation Area: Navigable waters within Narragansett Bay and the Providence River...

Code of Federal Regulations, 2011 CFR

2011-07-01

... navigation area (RNA). The Regulated Navigation Area (RNA) encompasses all of the navigable waters of...) Regulations. (1) All commercial vessels must: (i) Maintain a minimum 10% of the vessel's draft as an under... commercial vessel traffic in all locations within this RNA shall keep out of the way of the oncoming deep...

33 CFR 165.122 - Regulated Navigation Area: Navigable waters within Narragansett Bay and the Providence River...

Code of Federal Regulations, 2012 CFR

2012-07-01

... navigation area (RNA). The Regulated Navigation Area (RNA) encompasses all of the navigable waters of...) Regulations. (1) All commercial vessels must: (i) Maintain a minimum 10% of the vessel's draft as an under... commercial vessel traffic in all locations within this RNA shall keep out of the way of the oncoming deep...

7 CFR 959.4 - Production area.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 8 2011-01-01 2011-01-01 false Production area. 959.4 Section 959.4 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Regulating Handling Definitions § 959.4 Production area. Production area means the counties of Val Verde...

7 CFR 917.11 - Production area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Production area. 917.11 Section 917.11 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... CALIFORNIA Order Regulating Handling Definitions § 917.11 Production area. Production area means the State of...

78 FR 59902 - Regulated Navigation Area; Special Buzzards Bay Vessel Regulation, Buzzards Bay, MA

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-30

... DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 165 [Docket No. USCG-2011-0322] RIN 1625-AA11 Regulated Navigation Area; Special Buzzards Bay Vessel Regulation, Buzzards Bay, MA AGENCY: Coast Guard, DHS. ACTION: Notice of extension of comment period. SUMMARY: The Coast Guard is extending the...

78 FR 17781 - Transportation Worker Identification Credential (TWIC)-Reader Requirements

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-22

...In this Notice of Proposed Rulemaking (NPRM), the Coast Guard proposes to require owners and operators of certain vessels and facilities regulated by the Coast Guard to use electronic readers designed to work with the Transportation Worker Identification Credential (TWIC) as an access control measure. This NPRM also proposes additional requirements associated with electronic TWIC readers, including recordkeeping requirements for those owners and operators required to use an electronic TWIC reader, and security plan amendments to incorporate TWIC requirements. The TWIC program, including the proposed TWIC reader requirements in this rule, is an important component of the Coast Guard's multi-layered system of access control requirements and other measures designed to enhance maritime security. This rulemaking action, once final, would build upon existing Coast Guard regulations designed to ensure that only individuals who hold a TWIC are granted unescorted access to secure areas at those locations. The Coast Guard has already promulgated regulations pursuant to the Maritime Transportation Security Act of 2002 (MTSA) that require mariners and other individuals to obtain a TWIC and present it for inspection by security personnel prior to gaining access to such secure areas. By requiring certain vessels and facilities to perform TWIC inspections using electronic TWIC readers, this rulemaking would further enhance security at those locations. This rulemaking would also implement the Security and Accountability For Every Port Act of 2006 electronic TWIC reader requirements.

Depression and anger as risk factors underlying the relationship between maternal substance involvement and child abuse potential☆

PubMed Central

Hien, Denise; Cohen, Lisa R.; Caldeira, Nathilee A.; Flom, Peter; Wasserman, Gail

2013-01-01

Objective This study examines how emotion regulation deficits in the area of anger arousal and reactivity are associated with child abuse potential in mothers with substance use and depressive disorders in order to identify targeted areas for prevention and treatment. Methods A sample of 152 urban mothers was interviewed on measures of substance use, diagnosis of depression, anger arousal and reactivity, and child abuse potential. Results Linear hierarchical regressions revealed that anger arousal and reactivity exceeded diagnostic and demographic variables in predicting maternal child abuse potential. Additionally, anger arousal and reactivity was found to be a partial mediator of the relationship between diagnostic category and child abuse potential. Conclusions Findings are discussed in relation to a multifaceted model of child abuse potential which broadens the existing literature to include an examination of depression and emotion regulation in order to more fully understand how substance use and child abuse potential are linked. Practice implications Models and approaches which help clients to manage and regulate difficult feeling states, specifically anger, could be helpful, and may be most readily applied in such populations. PMID:20170960

Depression and anger as risk factors underlying the relationship between maternal substance involvement and child abuse potential.

PubMed

Hien, Denise; Cohen, Lisa R; Caldeira, Nathilee A; Flom, Peter; Wasserman, Gail

2010-02-01

This study examines how emotion regulation deficits in the area of anger arousal and reactivity are associated with child abuse potential in mothers with substance use and depressive disorders in order to identify targeted areas for prevention and treatment. A sample of 152 urban mothers was interviewed on measures of substance use, diagnosis of depression, anger arousal and reactivity, and child abuse potential. Linear hierarchical regressions revealed that anger arousal and reactivity exceeded diagnostic and demographic variables in predicting maternal child abuse potential. Additionally, anger arousal and reactivity was found to be a partial mediator of the relationship between diagnostic category and child abuse potential. Findings are discussed in relation to a multifaceted model of child abuse potential which broadens the existing literature to include an examination of depression and emotion regulation in order to more fully understand how substance use and child abuse potential are linked. Models and approaches which help clients to manage and regulate difficult feeling states, specifically anger, could be helpful, and may be most readily applied in such populations. Copyright (c) 2010. Published by Elsevier Ltd.

Noise pollution is pervasive in U.S. protected areas.

PubMed

Buxton, Rachel T; McKenna, Megan F; Mennitt, Daniel; Fristrup, Kurt; Crooks, Kevin; Angeloni, Lisa; Wittemyer, George

2017-05-05

Anthropogenic noise threatens ecological systems, including the cultural and biodiversity resources in protected areas. Using continental-scale sound models, we found that anthropogenic noise doubled background sound levels in 63% of U.S. protected area units and caused a 10-fold or greater increase in 21%, surpassing levels known to interfere with human visitor experience and disrupt wildlife behavior, fitness, and community composition. Elevated noise was also found in critical habitats of endangered species, with 14% experiencing a 10-fold increase in sound levels. However, protected areas with more stringent regulations had less anthropogenic noise. Our analysis indicates that noise pollution in protected areas is closely linked with transportation, development, and extractive land use, providing insight into where mitigation efforts can be most effective. Copyright © 2017, American Association for the Advancement of Science.

Structural analysis of the recognition of the negative regulator NmrA and DNA by the zinc finger from the GATA-type transcription factor AreA.

PubMed

Kotaka, Masayo; Johnson, Christopher; Lamb, Heather K; Hawkins, Alastair R; Ren, Jingshan; Stammers, David K

2008-08-29

Amongst the most common protein motifs in eukaryotes are zinc fingers (ZFs), which, although largely known as DNA binding modules, also can have additional important regulatory roles in forming protein:protein interactions. AreA is a transcriptional activator central to nitrogen metabolism in Aspergillus nidulans. AreA contains a GATA-type ZF that has a competing dual recognition function, binding either DNA or the negative regulator NmrA. We report the crystal structures of three AreA ZF-NmrA complexes including two with bound NAD(+) or NADP(+). The molecular recognition of AreA ZF-NmrA involves binding of the ZF to NmrA via hydrophobic and hydrogen bonding interactions through helices alpha1, alpha6 and alpha11. Comparison with an earlier NMR solution structure of AreA ZF-DNA complex by overlap of the AreA ZFs shows that parts of helices alpha6 and alpha11 of NmrA are positioned close to the GATA motif of the DNA, mimicking the major groove of DNA. The extensive overlap of DNA with NmrA explains their mutually exclusive binding to the AreA ZF. The presence of bound NAD(+)/NADP(+) in the NmrA-AreaA ZF complex, however, causes minimal structural changes. Thus, any regulatory effects on AreA function mediated by the binding of oxidised nicotinamide dinucleotides to NmrA in the NmrA-AreA ZF complex appear not to be modulated via protein conformational rearrangements.

Translational Regulation of PTEN/MMAC1 Expression in Prostate Cancer

DTIC Science & Technology

2005-05-01

Ac reporting burden for this collection of information is estimated to average 1 hour per response , including the time for reviewing instructions... responsible for constitutive production of the PTEN mRNAs with shorter 5’-UTRs in prostate cancer cells which would be compatible for cap-dependent...LIMITATION 18. NUMBER 19a. NAME OF RESPONSIBLE PERSON OF ABSTRACT OF PAGES a. REPORT b. ABSTRACT c. THIS PAGE 19b. TELEPHONE NUMBER (include area U U U UU

A framework to assess landscape structural capacity to provide regulating ecosystem services in West Africa.

PubMed

Inkoom, Justice Nana; Frank, Susanne; Greve, Klaus; Fürst, Christine

2018-03-01

The Sudanian savanna landscapes of West Africa are amongst the world's most vulnerable areas to climate change impacts. Inappropriate land use and agriculture management practices continuously impede the capacity of agricultural landscapes to provide ecosystem services (ES). Given the absence of practical assessment techniques to evaluate the landscape's capacity to provide regulating ES in this region, the goal of this paper is to propose an integrative assessment framework which combines remote sensing, geographic information systems, expert weighting and landscape metrics-based assessment. We utilized Analytical Hierarchical Process and Likert scale for the expert weighting of landscape capacity. In total, 56 experts from several land use and landscape management related departments participated in the assessment. Further, we adapted the hemeroby concept to define areas of naturalness while landscape metrics including Patch Density, Shannon's Diversity, and Shape Index were utilized for structural assessment. Lastly, we tested the reliability of expert weighting using certainty measurement rated by experts themselves. Our study focused on four regulating ES including flood control, pest and disease control, climate control, and wind erosion control. Our assessment framework was tested on four selected sites in the Vea catchment area of Ghana. The outcome of our study revealed that highly heterogeneous landscapes have a higher capacity to provide pest and disease control, while less heterogeneous landscapes have a higher potential to provide climate control. Further, we could show that the potential capacities to provide ecosystem services are underestimated by 15% if landscape structural aspects assessed through landscape metrics are not considered. We conclude that the combination of adapted land use and an optimized land use pattern could contribute considerably to lower climate change impacts in West African agricultural landscapes. Copyright © 2017 Elsevier Ltd. All rights reserved.

33 CFR 334.1030 - Oakland Inner Harbor adjacent to Alameda Facility, Naval Supply Center, Oakland; restricted area.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Alameda Facility, Naval Supply Center, Oakland; restricted area. 334.1030 Section 334.1030 Navigation and... RESTRICTED AREA REGULATIONS § 334.1030 Oakland Inner Harbor adjacent to Alameda Facility, Naval Supply Center, Oakland; restricted area. (a) The area. Within 100 feet of the Alameda Facility wharf. (b) The regulations...

33 CFR 334.1030 - Oakland Inner Harbor adjacent to Alameda Facility, Naval Supply Center, Oakland; restricted area.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Alameda Facility, Naval Supply Center, Oakland; restricted area. 334.1030 Section 334.1030 Navigation and... RESTRICTED AREA REGULATIONS § 334.1030 Oakland Inner Harbor adjacent to Alameda Facility, Naval Supply Center, Oakland; restricted area. (a) The area. Within 100 feet of the Alameda Facility wharf. (b) The regulations...

33 CFR 334.1030 - Oakland Inner Harbor adjacent to Alameda Facility, Naval Supply Center, Oakland; restricted area.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Alameda Facility, Naval Supply Center, Oakland; restricted area. 334.1030 Section 334.1030 Navigation and... RESTRICTED AREA REGULATIONS § 334.1030 Oakland Inner Harbor adjacent to Alameda Facility, Naval Supply Center, Oakland; restricted area. (a) The area. Within 100 feet of the Alameda Facility wharf. (b) The regulations...

33 CFR 334.1030 - Oakland Inner Harbor adjacent to Alameda Facility, Naval Supply Center, Oakland; restricted area.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Alameda Facility, Naval Supply Center, Oakland; restricted area. 334.1030 Section 334.1030 Navigation and... RESTRICTED AREA REGULATIONS § 334.1030 Oakland Inner Harbor adjacent to Alameda Facility, Naval Supply Center, Oakland; restricted area. (a) The area. Within 100 feet of the Alameda Facility wharf. (b) The regulations...

33 CFR 165.505 - Security Zone; Calvert Cliffs Nuclear Power Plant, Chesapeake Bay, Calvert County, Maryland.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) Persons desiring to transit the area of the security zone may contact the Captain of the Port at telephone... REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS Specific Regulated Navigation Areas and Limited Access Areas Fifth Coast Guard District § 165.505 Security Zone; Calvert Cliffs Nuclear Power Plant, Chesapeake...

Metropolitan Boston air quality control region: transportation control plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1975-02-28

The EPA is considering a number of amendments to the transportation control plan which it promulgated Nov. 8, 1973 for the Metropolitan Boston Intrastate Air Quality Control Region. Included in the proposed amendments is a revised regulation for reduction of commuter travel which would include students and employees. This program would be implemented in conjunction with the carpool matching program being developed by the Commonwealth of Massachusetts and the employee pass program offered by the Massachusetts Bay Transportation Authority. A new provision for limiting overall hydrocarbon emissions from major users of organic compounds is included. Also published are a proposalmore » for encouraging bicycle use, new proposals for controlling carbon monoxide levels outside the Boston core area, and a new procedure for periodic monitoring and updating of the plan. Other features of the original plan are retained with modifications in areas including the ceiling on the level of commercial parking spaces in the so-called ''freeze'' area, limitations of on-street commuter parking, a semiannual inspection and maintenance program, a retrofit program, and incentives for carpool and transit use.« less

On the road to recovery: Gasoline content regulations and child health.

PubMed

Marcus, Michelle

2017-07-01

Gasoline content regulations are designed to curb pollution and improve health, but their impact on health has not been quantified. By exploiting both the timing of regulation and spatial variation in children's exposure to highways, I estimate the effect of gasoline content regulation on pollution and child health. The introduction of cleaner-burning gasoline in California in 1996 reduced asthma admissions by 8% in high exposure areas. Reductions are greatest for areas downwind from highways and heavy traffic areas. Stringent gasoline content regulations can improve child health, and may diminish existing health disparities. Copyright © 2017 Elsevier B.V. All rights reserved.

33 CFR 165.817 - Arkansas River, Mile 118.2 to 125.4, Little Rock Arkansas-regulated navigation area.

Code of Federal Regulations, 2012 CFR

2012-07-01

... so as to avoid a meeting situation in the RNA. (d) Refer to 33 CFR 117.123 for drawbridge operation... navigation area. (a) Location. The following is a regulated navigation area (RNA): The waters of the Arkansas River between mile 118.2 and mile 125.4. (b) Regulations. Transit of the RNA is limited during periods...

33 CFR 165.817 - Arkansas River, Mile 118.2 to 125.4, Little Rock Arkansas-regulated navigation area.

Code of Federal Regulations, 2011 CFR

2011-07-01

... so as to avoid a meeting situation in the RNA. (d) Refer to 33 CFR 117.123 for drawbridge operation... navigation area. (a) Location. The following is a regulated navigation area (RNA): The waters of the Arkansas River between mile 118.2 and mile 125.4. (b) Regulations. Transit of the RNA is limited during periods...

33 CFR 165.817 - Arkansas River, Mile 118.2 to 125.4, Little Rock Arkansas-regulated navigation area.

Code of Federal Regulations, 2014 CFR

2014-07-01

... so as to avoid a meeting situation in the RNA. (d) Refer to 33 CFR 117.123 for drawbridge operation... navigation area. (a) Location. The following is a regulated navigation area (RNA): The waters of the Arkansas River between mile 118.2 and mile 125.4. (b) Regulations. Transit of the RNA is limited during periods...

33 CFR 165.817 - Arkansas River, Mile 118.2 to 125.4, Little Rock Arkansas-regulated navigation area.

Code of Federal Regulations, 2013 CFR

2013-07-01

... so as to avoid a meeting situation in the RNA. (d) Refer to 33 CFR 117.123 for drawbridge operation... navigation area. (a) Location. The following is a regulated navigation area (RNA): The waters of the Arkansas River between mile 118.2 and mile 125.4. (b) Regulations. Transit of the RNA is limited during periods...

33 CFR 165.817 - Arkansas River, Mile 118.2 to 125.4, Little Rock Arkansas-regulated navigation area.

Code of Federal Regulations, 2010 CFR

2010-07-01

... so as to avoid a meeting situation in the RNA. (d) Refer to 33 CFR 117.123 for drawbridge operation... navigation area. (a) Location. The following is a regulated navigation area (RNA): The waters of the Arkansas River between mile 118.2 and mile 125.4. (b) Regulations. Transit of the RNA is limited during periods...

Hydrologic analysis of the challenges facing water resources and sustainable development of Wadi Feiran basin, southern Sinai, Egypt

NASA Astrophysics Data System (ADS)

Ahmed, Ayman A.; Diab, Maghawri S.

2018-04-01

Wadi Feiran basin is one of the most promising areas in southern Sinai (Egypt) for establishing new communities and for growth in agriculture, tourism, and industry. The present challenges against development include water runoff hazards (flash flooding), the increasing water demand, and water scarcity and contamination. These challenges could be mitigated by efficient use of runoff and rainwater through appropriate management, thereby promoting sustainable development. Strategies include the mitigation of runoff hazards and promoting the natural and artificial recharge of aquifers. This study uses a watershed modeling system, geographic information system, and classification scheme to predict the effects of various mitigation options on the basin's water resources. Rainwater-harvesting techniques could save more than 77% of the basin's runoff (by volume), which could be used for storage and aquifer recharge. A guide map is provided that shows possible locations for the proposed mitigation options in the study basin. Appropriate measures should be undertaken urgently: mitigation of groundwater contamination (including effective sewage effluent management); regular monitoring of the municipal, industrial and agricultural processes that release contaminants; rationalization and regulation of the application of agro-chemicals to farmland; and regular monitoring of contaminants in groundwater. Stringent regulations should be implemented to prevent wastewater disposal to the aquifers in the study area.

76 FR 3489 - Revision of American Viticultural Area Regulations

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-20

... prescribe regulations for the labeling of wine, distilled spirits, and malt beverages. The FAA Act provides... appellations of origin on wine labels and in wine advertisements. Part 9 of the TTB regulations (27 CFR part 9...) of the TTB regulations (27 CFR 4.25(e)(1)(i)) defines a viticultural area for American wine as a...

33 CFR 401.50 - Anchorage areas.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Anchorage areas. 401.50 Section... TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Seaway Navigation § 401.50 Anchorage areas. Except in an... of the Seaway except in the following designated anchorage areas: (a) Point Fortier (Lake St. Louis...

33 CFR 401.50 - Anchorage areas.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Anchorage areas. 401.50 Section... TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Seaway Navigation § 401.50 Anchorage areas. Except in an... of the Seaway except in the following designated anchorage areas: (a) Point Fortier (Lake St. Louis...

33 CFR 401.50 - Anchorage areas.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Anchorage areas. 401.50 Section... TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Seaway Navigation § 401.50 Anchorage areas. Except in an... of the Seaway except in the following designated anchorage areas: (a) Point Fortier (Lake St. Louis...

33 CFR 401.50 - Anchorage areas.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Anchorage areas. 401.50 Section... TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Seaway Navigation § 401.50 Anchorage areas. Except in an... of the Seaway except in the following designated anchorage areas: (a) Point Fortier (Lake St. Louis...

microRNAs as regulators of adipogenic differentiation of mesenchymal stem cells.

PubMed

Hamam, Dana; Ali, Dalia; Kassem, Moustapha; Aldahmash, Abdullah; Alajez, Nehad M

2015-02-15

microRNAs (miRNAs) constitute complex regulatory network, fine tuning the expression of a myriad of genes involved in different biological and physiological processes, including stem cell differentiation. Mesenchymal stem cells (MSCs) are multipotent stem cells present in the bone marrow stroma, and the stroma of many other tissues, and can give rise to a number of mesoderm-type cells including adipocytes and osteoblasts, which form medullary fat and bone tissues, respectively. The role of bone marrow fat in bone mass homeostasis is an area of intensive investigation with the aim of developing novel approaches for enhancing osteoblastic bone formation through inhibition of bone marrow fat formation. A number of recent studies have reported several miRNAs that enhance or inhibit adipogenic differentiation of MSCs and with potential use in microRNA-based therapy to regulate adipogenesis in the context of treating bone diseases and metabolic disorders. The current review focuses on miRNAs and their role in regulating adipogenic differentiation of MSCs.

75 FR 15343 - Regulated Navigation Area: Narragansett Bay, RI and Mount Hope Bay, RI and MA, Including the...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-29

... the transit, and a requirement to maintain a minimum underkeel clearance to prevent groundings. Based...' at Mean Lower Low Water (MLLW), and a minimum channel width of 600'. While most shoaling was removed... number of small entities. The term ``small entities'' comprises small businesses, not-for-profit...

78 FR 11988 - Migratory Bird Subsistence Harvest in Alaska; Harvest Regulations for Migratory Birds in Alaska...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-21

...-management process involving the Service, the Alaska Department of Fish and Game, and Alaska Native... developed under a co-management process involving the Service, the Alaska Department of Fish and Game, and... Fish and Game's request to expand the Fairbanks North Star Borough excluded area to include the Central...

49 CFR 372.205 - Charleston, S.C.

Code of Federal Regulations, 2010 CFR

2010-10-01

... from a point beyond such zone, is partially exempt from regulation under 49 U.S.C. 13506(b)(1) includes and is comprised of all points as follows: (a) The municipality of Charleston, S.C., itself; (b) All... Charleston County, S.C., which are not within the areas described in paragraph (b) of this section; and those...

33 CFR 165.100 - Regulated Navigation Area: Navigable waters within the First Coast Guard District.

Code of Federal Regulations, 2012 CFR

2012-07-01

... destination(s). (C) Current and forecasted weather, including visibility, wind, and sea state for the... visibility, wind, and sea state. This information may be entered in either the voyage plan or towing vessel's log book. (C) The channels of VHF radio to monitor. (D) Other considerations such as availability of...

33 CFR 165.100 - Regulated Navigation Area: Navigable waters within the First Coast Guard District.

Code of Federal Regulations, 2013 CFR

2013-07-01

... destination(s). (C) Current and forecasted weather, including visibility, wind, and sea state for the... visibility, wind, and sea state. This information may be entered in either the voyage plan or towing vessel's log book. (C) The channels of VHF radio to monitor. (D) Other considerations such as availability of...

33 CFR 165.100 - Regulated Navigation Area: Navigable waters within the First Coast Guard District.

Code of Federal Regulations, 2014 CFR

2014-07-01

... destination(s). (C) Current and forecasted weather, including visibility, wind, and sea state for the... visibility, wind, and sea state. This information may be entered in either the voyage plan or towing vessel's log book. (C) The channels of VHF radio to monitor. (D) Other considerations such as availability of...

77 FR 6954 - Special Local Regulations; Safety and Security Zones; Recurring Events in Captain of the Port...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-10

... Events in Captain of the Port Long Island Sound Zone AGENCY: Coast Guard, DHS. ACTION: Final rule... Sector Long Island Sound Captain of the Port (COTP) Zone. These limited access areas include special... Sector Long Island Sound, telephone 203-468- 4544, email [email protected] . If you have questions...

77 FR 60050 - Special Regulations; Areas of the National Park System, Saguaro National Park, Bicycling

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-02

... hiking and equestrian trail that originates at the Loma Alta Trailhead and travels east through the..., including hiking, equestrian, and bicycle use. Shortly after acquiring the land, the NPS closed the route to... leadership after an adequate analysis of the benefits, impacts, and economic cost of alternative courses of...

The Role of Neuropeptide Y (NPY) In Uncontrolled Alcohol Drinking and Relapse Behavior Resulting From Exposure to Stressful Events

DTIC Science & Technology

2009-11-01

modulating neurobio - logical responses to ethanol and drugs of abuse, including the striatum, nucleus accumbens (NAc), ventral tegmental area (VTA...critically required for the regulation of energy homeostasis in mice. Mol Cell Biol 22, 5027–5035. Rasmussen, D.D., Bryant, C.A., Boldt, B.M., Colasurdo

33 CFR 165.T01-0220 - Regulated Navigation Area: Niantic Railroad Bridge Construction, Niantic, Connecticut.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., flashing light or other means, the operator of the vessel must proceed as directed. (5) Persons and vessels... enforcement of the RNA. If enforcement is suspended, the COTP will cause a notice of the suspension of... Notice to Mariners. Such notification will include the date and time that enforcement is suspended as...

33 CFR 165.T01-0220 - Regulated Navigation Area: Niantic Railroad Bridge Construction, Niantic, Connecticut.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., flashing light or other means, the operator of the vessel must proceed as directed. (5) Persons and vessels... enforcement of the RNA. If enforcement is suspended, the COTP will cause a notice of the suspension of... Notice to Mariners. Such notification will include the date and time that enforcement is suspended as...

Neural models on temperature regulation for cold-stressed animals

NASA Technical Reports Server (NTRS)

Horowitz, J. M.

1975-01-01

The present review evaluates several assumptions common to a variety of current models for thermoregulation in cold-stressed animals. Three areas covered by the models are discussed: signals to and from the central nervous system (CNS), portions of the CNS involved, and the arrangement of neurons within networks. Assumptions in each of these categories are considered. The evaluation of the models is based on the experimental foundations of the assumptions. Regions of the nervous system concerned here include the hypothalamus, the skin, the spinal cord, the hippocampus, and the septal area of the brain.

Bacteriological quality evaluation of seawater and oysters from the Jaranman-Saryangdo area, a designated shellfish growing area in Korea: Impact of inland pollution sources.

PubMed

Mok, Jong Soo; Lee, Ka Jeong; Kim, Poong Ho; Lee, Tae Seek; Lee, Hee Jung; Jung, Yeoun Joong; Kim, Ji Hoe

2016-07-15

From 2011 to 2013, we conducted a full sanitary survey of pollution sources in proximity to a designated shellfish growing area in Korea, and their impact on the sea area therein. From this area, 836 seawater samples and 93 oyster samples were examined to evaluate their bacteriological quality. There were 483 potential pollution sources in the drainage area of the Jaranman-Saryangdo area, including 38 sources discharging water. It demonstrates that while many pollution sources have been identified, no significant impact occurred within the designated shellfish growing area. Variations in fecal coliform (FC) levels in seawater were closely related to rainfall. The FC levels of seawater and oysters from the designated area met the regulation limits set by various countries. Our study indicates that the oysters produced in this area are apparently safe for raw consumption based on their bacterial quality. Copyright © 2016 Elsevier Ltd. All rights reserved.

7 CFR 905.15 - Regulation Area I.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Regulation Area I. 905.15 Section 905.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE ORANGES, GRAPEFRUIT, TANGERINES, AND...

48 CFR 970.1504-4 - Special cost or pricing areas.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Special cost or pricing areas. 970.1504-4 Section 970.1504-4 Federal Acquisition Regulations System DEPARTMENT OF ENERGY AGENCY... cost or pricing areas. ...

The development of advanced nursing practice globally.

PubMed

Sheer, Barbara; Wong, Frances Kam Yuet

2008-01-01

To examine the development of advanced nursing practice globally. Data were collected from documentary resources available in the International Nurse Practitioners/Advanced Practice Nurse Network (INP/APNN) of the International Council of Nurses. The areas examined were guided by the "key informant survey on advanced nursing practice self-administered questionnaire." Two core members of the INP/APNN who have rich experience in global advanced nursing development analyzed the data.A total of 14 countries and three regions from five continents were included in the analyses. The development of advanced nursing practice in these areas is facilitated by a need for better access to care in a cost-containment era and the enhancement of nursing education to postgraduate level. The mechanism for regulation of practice is in place in some countries. Confirms the development of advanced practice in nursing is a global trend. APNs can improve global health with points to enhanced education in nursing and regulation of advanced practice.

33 CFR 165.809 - Security Zones; Port of Port Lavaca-Point Comfort, Point Comfort, TX and Port of Corpus Christi...

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS Specific Regulated Navigation Areas and Limited Access Areas Eighth Coast Guard District § 165.809 Security Zones; Port of Port...) Location. The following area is designated as a security zone: all waters of the Corpus Christi Inner...

Physiological factors that regulate skin pigmentation.

PubMed

Yamaguchi, Yuji; Hearing, Vincent J

2009-01-01

More than 150 genes have been identified that affect skin color either directly or indirectly, and we review current understanding of physiological factors that regulate skin pigmentation. We focus on melanosome biogenesis, transport and transfer, melanogenic regulators in melanocytes, and factors derived from keratinocytes, fibroblasts, endothelial cells, hormones, inflammatory cells, and nerves. Enzymatic components of melanosomes include tyrosinase, tyrosinase-related protein 1, and dopachrome tautomerase, which depend on the functions of OA1, P, MATP, ATP7A, and BLOC-1 to synthesize eumelanins and pheomelanins. The main structural component of melanosomes is Pmel17/gp100/Silv, whose sorting involves adaptor protein 1A (AP1A), AP1B, AP2, and spectrin, as well as a chaperone-like component, MART-1. During their maturation, melanosomes move from the perinuclear area toward the plasma membrane. Microtubules, dynein, kinesin, actin filaments, Rab27a, melanophilin, myosin Va, and Slp2-a are involved in melanosome transport. Foxn1 and p53 up-regulate skin pigmentation via bFGF and POMC derivatives including alpha-MSH and ACTH, respectively. Other critical factors that affect skin pigmentation include MC1R, CREB, ASP, MITF, PAX3, SOX9/10, LEF-1/TCF, PAR-2, DKK1, SCF, HGF, GM-CSF, endothelin-1, prostaglandins, leukotrienes, thromboxanes, neurotrophins, and neuropeptides. UV radiation up-regulates most factors that increase melanogenesis. Further studies will elucidate the currently unknown functions of many other pigment genes/proteins. (c) 2009 International Union of Biochemistry and Molecular Biology, Inc.

33 CFR 100.35T09-0327 - Special Regulated Areas for summer events; Captain of the Port Lake Michigan Zone.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Special Regulated Areas for summer events; Captain of the Port Lake Michigan Zone. 100.35T09-0327 Section 100.35T09-0327 Navigation... OF LIFE ON NAVIGABLE WATERS § 100.35T09-0327 Special Regulated Areas for summer events; Captain of...

[Hunger and satiety factors in the regulation of pleasure associated with feeding behavior].

PubMed

Fetissov, Sergueï O

2016-01-01

Feeding is an instinctive behavior accompanied by rewarding feeling of pleasure during obtaining and ingesting food, corresponding to the preparatory and consummatory phases of motivated behavior, respectively. Perception of this emotional state together with alternating feelings of hunger and satiety drives the feeding behavior. Because alterations of feeding behavior including either overeating or anorexia may lead to obesity and cachexia, respectively, understanding the neurochemical mechanisms of regulation of feeding pleasure may help to develop new therapies of these diseases. The dopamine (DA) system of the mesolimbic projections plays a key role in behavioral reward in general and is also involved in regulating feeding-associated pleasure in the forebrain including the nucleus accumbens (NAc) and the lateral hypothalamic area (LHA). It suggests that this DA system can be selectively activated by factors specific to different types of motivated behavior including hunger- and satiety- related hormones. Indeed, central administrations of either orexigenic ghrelin or anorexigenic α-melanocyte-stimulating hormone (α-MSH) increase DA release in the NAc. However, DA has also been shown to inhibit food intake when injected into the LHA, historically known as a « hunger center », indicating DA functional involvement in regulation of both appetite and feeding pleasure. Although both NAc and LHA contain neurons expressing melanocortin receptors, only the LHA receives the α-MSH containing nerve terminals from the α-MSH producing neurons of the hypothalamic arcuate nucleus, the main relay of the peripheral hunger and satiety signals to the brain. A recent study showed that α-MSH in the LHA enhances satiety and inhibits feeding pleasure while potently stimulating DA release in this area during both preparatory and consummatory phases of feeding. It suggests that altered signaling by α-MSH to the DA system in the LHA may be involved in the pathophysiology of obesity and anorexia and the possible underlying mechanisms are discussed. © Société de Biologie, 2017.

33 CFR 165.T01-0394 - Regulated Navigation Area; Waldo-Hancock Bridge Demolition, Penobscot River, between Prospect and...

Code of Federal Regulations, 2013 CFR

2013-07-01

... a Regulated Navigation Area (RNA): All navigable waters of Penobscot River between Prospect, ME and...) Regulations. (1) The general regulations contained in 33 CFR 165.10, 165.11, and 165.13 apply within the RNA... New England. (3) Persons and vessels may request permission to enter the RNA during periods of...

Obesity prevention: the role of policies, laws and regulations.

PubMed

Swinburn, Boyd A

2008-06-05

The commercial drivers of the obesity epidemic are so influential that obesity can be considered a robust sign of commercial success - consumers are buying more food, more cars and more energy-saving machines. It is unlikely that these powerful economic forces will change sufficiently in response to consumer desires to eat less and move more or corporate desires to be more socially responsible. When the free market creates substantial population detriments and health inequalities, government policies are needed to change the ground rules in favour of population benefits.Concerted action is needed from governments in four broad areas: provide leadership to set the agenda and show the way; advocate for a multi-sector response and establish the mechanisms for all sectors to engage and enhance action; develop and implement policies (including laws and regulations) to create healthier food and activity environments, and; secure increased and continued funding to reduce obesogenic environments and promote healthy eating and physical activity.Policies, laws and regulations are often needed to drive the environmental and social changes that, eventually, will have a sustainable impact on reducing obesity. An 'obesity impact assessment' on legislation such as public liability, urban planning, transport, food safety, agriculture, and trade may identify 'rules' which contribute to obesogenic environments. In other areas, such as marketing to children, school food, and taxes/levies, there may be opportunities for regulations to actively support obesity prevention. Legislation in other areas such as to reduce climate change may also contribute to obesity prevention ('stealth interventions'). A political willingness to use policy instruments to drive change will probably be an early hallmark of successful obesity prevention.

Eating on the fly: function and regulation of autophagy during cell growth, survival and death in Drosophila.

PubMed

Neufeld, Thomas P; Baehrecke, Eric H

2008-07-01

Significant progress has been made over recent years in defining the normal progression and regulation of autophagy, particularly in cultured mammalian cells and yeast model systems. However, apart from a few notable exceptions, our understanding of the physiological roles of autophagy has lagged behind these advances, and identification of components and features of autophagy unique to higher eukaryotes also remains a challenge. In this review we describe recent insights into the roles and control mechanisms of autophagy gained from in vivo studies in Drosophila. We focus on potential roles of autophagy in controlling cell growth and death, and describe how the regulation of autophagy has evolved to include metazoan-specific signaling pathways. We discuss genetic screening approaches that are being used to identify novel regulators and effectors of autophagy, and speculate about areas of research in this system likely to bear fruit in future studies.

Autophagy promotes degradation of internalized collagen and regulates distribution of focal adhesions to suppress cell adhesion

PubMed Central

Kawano, Shinichi; Esaki, Motohiro; Torisu, Kumiko; Matsuno, Yuichi; Kitazono, Takanari

2017-01-01

ABSTRACT Adhesion of cells to the extracellular matrix (ECM) via focal adhesions (FAs) is crucial for cell survival, migration, and differentiation. Although the regulation of FAs, including by integrins and the ECM, is important to cell behavior, how FAs are regulated is not well known. Autophagy is induced by both cell adhesion and cell detachment. Here, we showed that autophagosomes are located close to internalized collagen and paxillin, which is a well-known marker of FAs. Autophagy-deficient cells showed increased levels of internalized collagen compared with control cells. Moreover, paxillin exhibited a more peripheral distribution and the area of paxillin was increased, and adhesion-induced focal adhesion kinase signaling was impaired and adhesion was enhanced, in autophagy-deficient cells. These results suggest that autophagy suppressed cell adhesion by regulating internalized ECM and FAs. PMID:28970230

78 FR 28170 - Regulated Navigation Area; Southern Oahu Tsunami Vessel Evacuation; Honolulu, HI

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-14

... DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 165 [Docket No. USCG-2012-0080] RIN 1625-AA11 Regulated Navigation Area; Southern Oahu Tsunami Vessel Evacuation; Honolulu, HI AGENCY: Coast... waters contained within an area composing of an area on the southern side of Oahu, HI. The RNA extends...

7 CFR 966.4 - Production area and regulated area.

Code of Federal Regulations, 2012 CFR

2012-01-01

...) Production area means the counties of Pinellas, Hillsborough, Polk, Osceola, and Brevard in the State of Florida, and all the counties of that State situated south of such counties. (b) Regulated area means that portion of the State of Florida which is bounded by the Suwannee River, the Georgia border, the Atlantic...

7 CFR 966.4 - Production area and regulated area.

Code of Federal Regulations, 2013 CFR

2013-01-01

...) Production area means the counties of Pinellas, Hillsborough, Polk, Osceola, and Brevard in the State of Florida, and all the counties of that State situated south of such counties. (b) Regulated area means that portion of the State of Florida which is bounded by the Suwannee River, the Georgia border, the Atlantic...

7 CFR 966.4 - Production area and regulated area.

Code of Federal Regulations, 2011 CFR

2011-01-01

...) Production area means the counties of Pinellas, Hillsborough, Polk, Osceola, and Brevard in the State of Florida, and all the counties of that State situated south of such counties. (b) Regulated area means that portion of the State of Florida which is bounded by the Suwannee River, the Georgia border, the Atlantic...

7 CFR 966.4 - Production area and regulated area.

Code of Federal Regulations, 2014 CFR

2014-01-01

...) Production area means the counties of Pinellas, Hillsborough, Polk, Osceola, and Brevard in the State of Florida, and all the counties of that State situated south of such counties. (b) Regulated area means that portion of the State of Florida which is bounded by the Suwannee River, the Georgia border, the Atlantic...

32 CFR 761.20 - Additional regulations governing persons and vessels in Naval Defensive Sea Areas.

Code of Federal Regulations, 2011 CFR

2011-07-01

... vessels in Naval Defensive Sea Areas. 761.20 Section 761.20 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY ISLANDS UNDER NAVY JURISDICTION NAVAL DEFENSIVE SEA AREAS; NAVAL AIRSPACE... Instructions § 761.20 Additional regulations governing persons and vessels in Naval Defensive Sea Areas. (a) By...

Materials Compatibility Testing in RSRM ODC: Free Cleaner Selection

NASA Technical Reports Server (NTRS)

Keen, Jill M.; Sagers, Neil W.; McCool, Alex (Technical Monitor)

2001-01-01

Government regulations have mandated production phase-outs of a number of solvents, including 1,1,1-trichloroethane, an ozone-depleting chemical (ODC). This solvent was used extensively in the production of the Reusable Solid Rocket Motors (RSRMs) for the Space Shuttle. Many tests have been performed to identify replacement cleaners. One major area of concern in the selection of a new cleaner has been compatibility. Some specific areas considered included cleaner compatibility with non-metallic surfaces, painted surfaces, support materials such as gloves and wipers as well as corrosive properties of the cleaners on the alloys used on these motors. The intent of this paper is to summarize the test logic, methodology, and results acquired from testing the many cleaner and material combinations.

Minireview: Hey U(PS): Metabolic and Proteolytic Homeostasis Linked via AMPK and the Ubiquitin Proteasome System

PubMed Central

Ronnebaum, Sarah M.; Patterson, Cam

2014-01-01

One of the master regulators of both glucose and lipid cellular metabolism is 5′-AMP-activated protein kinase (AMPK). As a metabolic pivot that dynamically responds to shifts in nutrient availability and stress, AMPK dysregulation is implicated in the underlying molecular pathology of a variety of diseases, including cardiovascular diseases, diabetes, cancer, neurological diseases, and aging. Although the regulation of AMPK enzymatic activity by upstream kinases is an active area of research, less is known about regulation of AMPK protein stability and activity by components of the ubiquitin-proteasome system (UPS), the cellular machinery responsible for both the recognition and degradation of proteins. Furthermore, there is growing evidence that AMPK regulates overall proteasome activity and individual components of the UPS. This review serves to identify the current understanding of the interplay between AMPK and the UPS and to promote further exploration of the relationship between these regulators of energy use and amino acid availability within the cell. PMID:25099013

Affect regulation, brain development, and behavioral/emotional health in adolescence.

PubMed

Dahl, R E

2001-01-01

This paper addresses the importance of affect regulation (AR) in relation to a broad range of behavioral and emotional health problems that emerge during adolescence. AR is defined as the adaptive modulation of emotional experience to serve a goal or purpose. This conceptualization of AR emphasizes the use of cognitive skills to guide, inhibit, or modify emotion and behavior, including the expression of emotional responses, in learned, strategic ways-skills that ultimately underpin adult levels of social maturity and the ability to show "responsible" behavior across a range of emotional situations. Neurobehavioral systems that subserve these AR skills include areas of the inferior and orbital prefrontal cortex (PFC), with rich interconnections to several limbic structures and other cortical areas, including the dorsolateral PFC. Adolescence represents an important developmental period in the functional maturation of adult AR skills; it is also a critical time in the development of clinical disorders of AR (eg, rates of depression increase dramatically and gender differences in depression emerge). Maturational changes in AR that occur during adolescence-particularly with respect to the role of emotions influencing responsible decision making-are also relevant to understanding key aspects of the developmental pathways of some behavioral health problems, such as alcohol use and nicotine dependence. A strong case is made for developmental research in affective neuroscience aimed at this important maturational period, particularly the kind of transdisciplinary research leading toward mechanistic understanding of the development of adolescent-onset disorders. Improving understanding in these areas could ultimately lead to the development of early interventions in targeted high-risk populations, and has enormous clinical and social policy relevance.

Nanotechnology regulation: a study in claims making.

PubMed

Malloy, Timothy F

2011-01-25

There appears to be consensus on the notion that the hazards of nanotechnology are a social problem in need of resolution, but much dispute remains over what that resolution should be. There are a variety of potential policy tools for tackling this challenge, including conventional direct regulation, self-regulation, tort liability, financial guarantees, and more. The literature in this area is replete with proposals embracing one or more of these tools, typically using conventional regulation as a foil in which its inadequacy is presented as justification for a new proposed approach. At its core, the existing literature raises a critical question: What is the most effective role of government as regulator in these circumstances? This article explores that question by focusing upon two policy approaches in particular: conventional regulation and self-regulation, often described as hard law and soft law, respectively. Drawing from the sociology of social problems, the article examines the soft law construction of the nanotechnology problem and the associated solutions, with emphasis on the claims-making strategies used. In particular, it critically examines the rhetoric and underlying grounds for the soft law approach. It also sets out the grounds and framework for an alternative construction and solution-the concept of iterative regulation.

CPD and revalidation: our future is happening now.

PubMed

Austin, Zubin

2013-01-01

Around the world, there is growing interest in ensuring health professionals (including pharmacists) maintain and demonstrate competency throughout their careers. Mechanisms to assure regulators, employers, colleagues, and--most importantly--patients that practitioners are indeed competent to provide safe and effective care are evolving, but generally include both continuing professional development (CPD) and assessment components. This commentary reviews current work in these areas within the pharmacy profession, in both the UK and the US. Copyright © 2013 Elsevier Inc. All rights reserved.

48 CFR 237.7002 - Area of performance and distribution of contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Area of performance and distribution of contracts. 237.7002 Section 237.7002 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING Mortuary...

Aldehyde dehydrogenase induction in arsenic-exposed rat bladder epithelium.

PubMed

Huang, Ya-Chun; Yu, Hsin-Su; Chai, Chee-Yin

2016-01-01

Arsenic is widely distributed in the environment. Many human cancers, including urothelial carcinoma (UC), show a dose-dependent relationship with arsenic exposure in the south-west coast of Taiwan (also known as the blackfoot disease (BFD) areas). However, the molecular mechanisms of arsenic-mediated UC carcinogenesis has not yet been defined. In vivo study, the rat bladder epithelium were exposed with arsenic for 48 h. The proteins were extracted from untreated and arsenic-treated rat bladder cells and utilized two-dimensional gel electrophoresis and mass spectrometry. Selected peptides were extracted from the gel and identified by quadrupole-time of flight (Q-TOF) Ultima-Micromass spectra. The significantly difference expression of proteins in arsenic-treated groups as compared with untreated groups was confirmed by immunohistochemistry (IHC) and western blotting. We found that thirteen proteins were down-regulated and nine proteins were up-regulated in arsenic-treated rat bladder cells when compared with untreated groups. The IHC and western blotting results confirmed that aldehyde dehydrogenase (ALDH) protein was up-regulated in arsenic-treated rat bladder epithelium. Expression of ALDH protein was significantly higher in UC patients from BFD areas than those from non-BFD areas using IHC (p=0.018). In conclusion, the ALDH protein expression could be used as molecular markers for arsenic-induced transformation. Copyright © 2015 Elsevier GmbH. All rights reserved.

Regulatory physiology discipline science plan

NASA Technical Reports Server (NTRS)

1991-01-01

The focus of the Regulatory Physiology discipline of the Space Physiology and Countermeasures Program is twofold. First, to determine and study how microgravity and associated factors of space flight affect the regulatory mechanisms by which humans adapt and achieve homeostasis and thereby regulate their ability to respond to internal and external signals; and, second, to study selected physiological systems that have been demonstrated to be influenced by gravity. The Regulatory Physiology discipline, as defined here, is composed of seven subdisciplines: (1) Circadian Rhythms, (2) Endocrinology, (3) Fluid and Electrolyte Regulation, (4) Hematology, (5) Immunology, (6) Metabolism and Nutrition, and (7) Temperature Regulation. The purpose of this Discipline Science Plan is to provide a conceptual strategy for NASA's Life Sciences Division research and development activities in the area of regulatory physiology. It covers the research areas critical to NASA's programmatic requirements for the Extended-Duration Orbiter, Space Station Freedom, and exploration mission science activities. These science activities include ground-based and flight; basic, applied, and operational; and animal and human research and development. This document summarizes the current status of the program, outlines available knowledge, establishes goals and objectives, identifies science priorities, and defines critical questions in regulatory physiology. It contains a general plan that will be used by both NASA Headquarters Program Offices and the field centers to review and plan basic, applied, and operational intramural and extramural research and development activities in this area.

Vasopressin Innervation of the Mouse (Mus musculus) Brain and Spinal Cord

PubMed Central

Rood, Benjamin D.; De Vries, Geert J.

2014-01-01

The neuropeptide vasopressin (AVP) has been implicated in the regulation of numerous physiological and behavioral processes. Although mice have become an important model for studying this regulation, there is no comprehensive description of AVP distribution in the mouse brain and spinal cord. With C57BL/6 mice, we used immunohistochemistry to corroborate the location of AVP-containing cells and to define the location of AVP-containing fibers throughout the mouse central nervous system. We describe AVP-immunoreactive (-ir) fibers in midbrain, hindbrain, and spinal cord areas, which have not previously been reported in mice, including innervation of the ventral tegmental area, dorsal and median raphe, lateral and medial parabrachial, solitary, ventrolateral periaqueductal gray, and interfascicular nuclei. We also provide a detailed description of AVP-ir innervation in heterogenous regions such as the amygdala, bed nucleus of the stria terminalis, and ventral forebrain. In general, our results suggest that, compared with other species, the mouse has a particularly robust and widespread distribution of AVP-ir fibers, which, as in other species, originates from a number of different cell groups in the telencephalon and diencephalon. Our data also highlight the robust nature of AVP innervation in specific regulatory nuclei, such as the ventral tegmental area and dorsal raphe nucleus among others, that are implicated in the regulation of many behaviors. PMID:21456024

7 CFR 906.4 - Production area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Production area. 906.4 Section 906.4 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... RIO GRANDE VALLEY IN TEXAS Order Regulating Handling Definitions § 906.4 Production area. Production...

Oil, biological communities and contingency planning

USGS Publications Warehouse

Albers, P.H.; Frink, Lynne; Ball-Weir, Katherine; Smith, Charlotte

1995-01-01

The Oil Pollution Act of 1990 mandates the inclusion of a fish and wildlife response plan in the National Contingency Plan (NCP) and the creation of Area Committees that must develop an Area Contingency Plan (ACP). Area Contingency Plans must include a detailed annex containing a Fish and Wildlife and Sensitive Environments Plan. Tank vessels, offshore facilities, and certain onshore facilities must have response plans consistent with the requirements of the NCP and the ACP. New regulations to supersede the Type A and B procedures of the Natural Resources Damage Assessment Regulations are being developed for oil spills. Currently, four assessment methods have been proposed: (1) Type A, (2) comprehensive (Type B), (3) intermediate (between types A and B), and (4) compensation tables. The Oil Spill Liability Trust Fund is approaching its ceiling of $1 billion, but only $50 million has been appropriated. Effective biological contingency planning requires extensive knowledge of (1) the environmental fate of petroleum, (2) the effects of petroleum on organisms, (3) the existing biological resources, and (4) the establishment of a system of biological priorities. The characteristics and fate of petroleum and the biological effects of petroleum are reviewed. Assessment of biological resources includes plant and animal distributions, important habitat, endangered or threatened species, and economic considerations. The establishment by Area Committees of priorities for environmental protection, injury assessment, and restoration will promote efficient spill response. Three special issues are discussed: (1) improving our ability to restore natural resources, (2) the potential role of biological diversity in spill response planning, and (3) planning for animal rehabilitation.

76 FR 71928 - Defense Federal Acquisition Regulation Supplement; Updates to Wide Area WorkFlow (DFARS Case 2011...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-21

... Defense Federal Acquisition Regulation Supplement; Updates to Wide Area WorkFlow (DFARS Case 2011-D027... Wide Area WorkFlow (WAWF) and TRICARE Encounter Data System (TEDS). WAWF, which electronically... civil emergencies, when access to Wide Area WorkFlow by those contractors is not feasible; (4) Purchases...

Denitrification potential of riparian soils in relation to multiscale spatial environmental factors: a case study of a typical watershed, China.

PubMed

Wei, Jianbing; Feng, Hao; Cheng, Quanguo; Gao, Shiqian; Liu, Haiyan

2017-02-01

The objective of this study was to test the hypothesis that environmental regulators of riparian zone soil denitrification potential differ according to spatial scale within a watershed; consequently, a second objective was to provide spatial strategies for conserving and restoring the purification function of runoff in riparian ecosystems. The results show that soil denitrification in riparian zones was more heterogeneous at the profile scale than at the cross-section and landscape scales. At the profile scale, biogeochemical factors (including soil total organic carbon, total nitrogen, and nitrate-nitrogen) were the major direct regulators of the spatial distribution of soil denitrification enzyme activity (DEA). At the cross-section scale, factors included distance from river bank and vegetation density, while landscape-scale factors, including topographic index, elevation, and land use types, indirectly regulated the spatial distribution of DEA. At the profile scale, soil DEA was greatest in the upper soil layers. At the cross-section scale, maximum soil DEA occurred in the mid-part of the riparian zone. At the landscape scale, soil DEA showed an increasing trend towards downstream sites, except for those in urbanized areas.

48 CFR 52.226-3 - Disaster or Emergency Area Representation.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Disaster or Emergency Area Representation. 52.226-3 Section 52.226-3 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 52...

48 CFR 52.226-3 - Disaster or Emergency Area Representation.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Disaster or Emergency Area Representation. 52.226-3 Section 52.226-3 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 52...

7 CFR 905.16 - Regulation Area II.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Regulation Area II. 905.16 Section 905.16 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... the St. Johns River; thence along the main channel of the St. Johns River and through Lake Harney...

78 FR 23849 - Inland Waterways Navigation Regulation: Sacramento River, CA

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-23

...-AB95 Inland Waterways Navigation Regulation: Sacramento River, CA AGENCY: Coast Guard, DHS. ACTION... Regulation: Sacramento River, CA'' in the Federal Register (78 FR 4785). That rule announced our intent to... the Decker Island restricted anchorage area in the Sacramento River. The restricted anchorage area was...

33 CFR 334.1390 - Pacific Ocean off the Pacific Missile Range Facility at Barking Sands, Island of Kauai, Hawaii...

Code of Federal Regulations, 2014 CFR

2014-07-01

... Missile Range Facility at Barking Sands, Island of Kauai, Hawaii; danger zone. 334.1390 Section 334.1390... AND RESTRICTED AREA REGULATIONS § 334.1390 Pacific Ocean off the Pacific Missile Range Facility at... Pacific Missile Range Facility range boats, beach markings including beach signs along the north and south...

77 FR 12761 - Special Regulations; Areas of the National Park System, Saguaro National Park, Bicycle Route

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-02

..., preserve, and interpret the monument's resources, and to provide for education and benefit to the public... worldwide as an icon of the American Southwest. The Hope Camp Trail is a 2.8 mile long hiking and equestrian... the route to be used for recreational purposes, including hiking, equestrian and bicycle use. Shortly...

75 FR 754 - Safety Zone and Regulated Navigation Area, Chicago Sanitary and Ship Canal, Romeoville, IL

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-06

... barriers would affect a human body if immersed in the water. The NEDU final report concluded that the possible effects to a human body if immersed in the water include paralysis of body muscles, inability to... body of your document so that we can contact you if we have questions regarding your submission. To...

78 FR 69310 - Endangered and Threatened Species; Protective Regulations for the Gulf of Maine Distinct...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-19

.... Receivers placed in areas of the Delaware and Hudson rivers, including low-salinity waters (salinity values... Atlantic sturgeon appeared one or more times within low-salinity waters (less than 0.5 ppt) of the Delaware... York Bight DPS sturgeon (29 of 58 captured) occurred in low- salinity waters of either the Delaware or...

Lead in American Schools: What School Districts Should and Should Not Do.

ERIC Educational Resources Information Center

Institute for Environmental Assessment, Brooklyn Park, MN.

This paper examines the lead issue in school buildings, noting that even minimal exposures to lead can create diagnosable health problems in children. It includes comments about current regulations and laws pertaining to the areas of soil, water, air, debris disposal, surfaces, and level of lead in the blood. It also lists responses to lead that…

The Effects of a Mindfulness and Biofeedback Program on the On- and Off-Task Behaviors of Students with Emotional Behavioral Disorders

ERIC Educational Resources Information Center

Rush, Karena S.; Golden, Maria E.; Mortenson, Bruce P.; Albohn, Daniel; Horger, Melissa

2017-01-01

Research suggests that mind-body techniques are useful for enhancing self-regulatory behaviors, including attention and emotional regulation. The majority of research in this area focuses on adult behavior. However, there has been a growing interest in using mindfulness techniques with children and more recently, in the school setting. Students…

7 CFR 1007.2 - Southeast marketing area.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 9 2014-01-01 2013-01-01 true Southeast marketing area. 1007.2 Section 1007.2 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE SOUTHEAST MARKETING AREA Order Regulating...

7 CFR 1006.2 - Florida marketing area.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 9 2012-01-01 2012-01-01 false Florida marketing area. 1006.2 Section 1006.2 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE FLORIDA MARKETING AREA Order Regulating...

7 CFR 1006.2 - Florida marketing area.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 9 2013-01-01 2013-01-01 false Florida marketing area. 1006.2 Section 1006.2 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE FLORIDA MARKETING AREA Order Regulating...

7 CFR 1001.2 - Northeast marketing area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 9 2010-01-01 2009-01-01 true Northeast marketing area. 1001.2 Section 1001.2 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE NORTHEAST MARKETING AREA Order Regulating...

7 CFR 1033.2 - Mideast marketing area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 9 2010-01-01 2009-01-01 true Mideast marketing area. 1033.2 Section 1033.2 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE MIDEAST MARKETING AREA Order Regulating...

7 CFR 1033.2 - Mideast marketing area.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 9 2012-01-01 2012-01-01 false Mideast marketing area. 1033.2 Section 1033.2 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE MIDEAST MARKETING AREA Order Regulating...

7 CFR 1006.2 - Florida marketing area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 9 2010-01-01 2009-01-01 true Florida marketing area. 1006.2 Section 1006.2 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE FLORIDA MARKETING AREA Order Regulating...

7 CFR 1131.2 - Arizona marketing area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 9 2010-01-01 2009-01-01 true Arizona marketing area. 1131.2 Section 1131.2 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE ARIZONA MARKETING AREA Order Regulating...

7 CFR 1007.2 - Southeast marketing area.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 9 2011-01-01 2011-01-01 false Southeast marketing area. 1007.2 Section 1007.2 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE SOUTHEAST MARKETING AREA Order Regulating...

7 CFR 1007.2 - Southeast marketing area.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 9 2013-01-01 2013-01-01 false Southeast marketing area. 1007.2 Section 1007.2 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE SOUTHEAST MARKETING AREA Order Regulating...

7 CFR 1032.2 - Central marketing area.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 9 2011-01-01 2011-01-01 false Central marketing area. 1032.2 Section 1032.2 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE CENTRAL MARKETING AREA Order Regulating...

7 CFR 1131.2 - Arizona marketing area.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 9 2014-01-01 2013-01-01 true Arizona marketing area. 1131.2 Section 1131.2 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE ARIZONA MARKETING AREA Order Regulating...

7 CFR 1033.2 - Mideast marketing area.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 9 2014-01-01 2013-01-01 true Mideast marketing area. 1033.2 Section 1033.2 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE MIDEAST MARKETING AREA Order Regulating...

7 CFR 1006.2 - Florida marketing area.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 9 2014-01-01 2013-01-01 true Florida marketing area. 1006.2 Section 1006.2 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE FLORIDA MARKETING AREA Order Regulating...

7 CFR 1126.2 - Southwest marketing area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 9 2010-01-01 2009-01-01 true Southwest marketing area. 1126.2 Section 1126.2 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE SOUTHWEST MARKETING AREA Order Regulating...

7 CFR 1032.2 - Central marketing area.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 9 2014-01-01 2013-01-01 true Central marketing area. 1032.2 Section 1032.2 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE CENTRAL MARKETING AREA Order Regulating...