Almost certain escape from black holes in final state projection models.

PubMed

Lloyd, Seth

2006-02-17

Recent models of the black-hole final state suggest that quantum information can escape from a black hole by a process akin to teleportation. These models rely on a controversial process called final-state projection. This Letter discusses the self-consistency of the final-state projection hypothesis and investigates escape from black holes for arbitrary final states and for generic interactions between matter and Hawking radiation. Quantum information escapes with fidelity approximately = (8/3pi)2: only half a bit of quantum information is lost on average, independent of the number of bits that escape from the hole.

Final Rule for Industrial Process Cooling Towers: Fact Sheet

EPA Pesticide Factsheets

Fact sheet concerning a final rule to reduce air toxics emissions from industrial process cooling towers. Air toxics are those pollutants known or suspected of causing cancer or other serious health effects.

Microstructure evolution and tensile properties of Zr-2.5wt%Nb pressure tubes processed from billets with different microstructures

NASA Astrophysics Data System (ADS)

Kapoor, K.; Saratchandran, N.; Muralidharan, K.

1999-02-01

Starting with identical ingots, billets having different microstructures were obtained by three different processing methods for fabrication of Zr-2.5wt%Nb pressure tubes. The billets were further processed by hot extrusion and cold Pilger tube reducing to the finished product. Microstructural characterization was done at each stage of processing. The effects of the initial billet microstructure on the intermediate and final microstructure and mechanical property results were determined. It was found that the structure at each stage and the final mechanical properties depend strongly on the initial billet microstructure. The structure at the final stage consists of elongated alpha zirconium grains with a network of metastable beta zirconium phase. Some of this metastable phase transforms into stable beta niobium during thermomechanical processing. Billets with quenched structure resulted in less beta niobium at the final stage. The air cooled billets resulted in a large amount of beta niobium. The tensile properties, especially the percentage elongation, were found to vary for the different methods. Higher percentage elongation was observed for billets having quenched structure. Extrusion and forging did not produce any characteristic differences in the properties. The results were used to select a process flow sheet which yields the desired mechanical properties with suitable microstructure in the final product.

An Assessment of Decision-Making Processes: Evaluation of Where Land Protection Planning Can Incorporate Climate Change Information (Final Report)

EPA Science Inventory

EPA announced the availability of the final report, An Assessment of Decision-Making Processes: Evaluation of Where Land Protection Planning Can Incorporate Climate Change Information. This report is a review of decision-making processes of selected land protection prog...

75 FR 12988 - National Emission Standards for Hazardous Air Pollutants for Area Sources: Asphalt Processing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-18

... roofing manufacturing area source category (74 FR 63236). Following signature of this final rule, EPA...). Following signature of the final asphalt processing and asphalt roofing manufacturing area source standards...

Effect of Thermomechanical Processing on Microstructure, Texture Evolution, and Mechanical Properties of Al-Mg-Si-Cu Alloys with Different Zn Contents

NASA Astrophysics Data System (ADS)

Wang, X. F.; Guo, M. X.; Chen, Y.; Zhu, J.; Zhang, J. S.; Zhuang, L. Z.

2017-07-01

The effect of thermomechanical processing on microstructure, texture evolution, and mechanical properties of Al-Mg-Si-Cu alloys with different Zn contents was studied by mechanical properties, microstructure, and texture characterization in the present study. The results show that thermomechanical processing has a significant influence on the evolution of microstructure and texture and on the final mechanical properties, independently of Zn contents. Compared with the T4P-treated (first preaged at 353 K (80 °C) for 12 hours and then naturally aged for 14 days) sheets with high final cold rolling reduction, the T4P-treated sheets with low final cold rolling reduction possess almost identical strength and elongation and higher average r values. Compared with the intermediate annealed sheets with high final cold rolling reduction, the intermediate annealed sheets with low final cold rolling reduction contain a higher number of particles with a smaller size. After solution treatment, in contrast to the sheets with high final cold rolling reduction, the sheets with low final cold rolling reduction possess finer grain structure and tend to form a weaker recrystallization texture. The recrystallization texture may be affected by particle distribution, grain size, and final cold rolling texture. Finally, the visco-plastic self-consistent (VPSC) model was used to predict r values.

Improving global CD uniformity by optimizing post-exposure bake and develop sequences

NASA Astrophysics Data System (ADS)

Osborne, Stephen P.; Mueller, Mark; Lem, Homer; Reyland, David; Baik, KiHo

2003-12-01

Improvements in the final uniformity of masks can be shrouded by error contributions from many sources. The final Global CD Uniformity (GCDU) of a mask is degraded by individual contributions of the writing tool, the Post Applied Bake (PAB), the Post Exposure Bake (PEB), the Develop sequence and the Etch step. Final global uniformity will improve by isolating and minimizing the variability of the PEB and Develop. We achieved this de-coupling of the PEB and Develop process from the whole process stream by using "dark loss" which is the loss of unexposed resist during the develop process. We confirmed a correspondence between Angstroms of dark loss and nanometer sized deviations in the chrome CD. A plate with a distinctive dark loss pattern was related to a nearly identical pattern in the chrome CD. This pattern was verified to have originated during the PEB process and displayed a [Δ(Final CD)/Δ(Dark Loss)] ratio of 6 for TOK REAP200 resist. Previous papers have reported a sensitive linkage between Angstroms of dark loss and nanometers in the final uniformity of the written plate. These initial studies reported using this method to improve the PAB of resists for greater uniformity of sensitivity and contrast. Similarly, this paper demonstrates an outstanding optimization of PEB and Develop processes.

10 CFR 950.32 - Final determination on covered events.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Final determination on covered events. 950.32 Section 950... Process § 950.32 Final determination on covered events. (a) If the parties reach a Final Determination on Covered Events through mediation, or Summary Binding Decision as set forth in this subpart, the Final...

10 CFR 950.32 - Final determination on covered events.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Final determination on covered events. 950.32 Section 950... Process § 950.32 Final determination on covered events. (a) If the parties reach a Final Determination on Covered Events through mediation, or Summary Binding Decision as set forth in this subpart, the Final...

10 CFR 950.32 - Final determination on covered events.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Final determination on covered events. 950.32 Section 950... Process § 950.32 Final determination on covered events. (a) If the parties reach a Final Determination on Covered Events through mediation, or Summary Binding Decision as set forth in this subpart, the Final...

10 CFR 950.32 - Final determination on covered events.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Final determination on covered events. 950.32 Section 950... Process § 950.32 Final determination on covered events. (a) If the parties reach a Final Determination on Covered Events through mediation, or Summary Binding Decision as set forth in this subpart, the Final...

10 CFR 950.32 - Final determination on covered events.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Final determination on covered events. 950.32 Section 950... Process § 950.32 Final determination on covered events. (a) If the parties reach a Final Determination on Covered Events through mediation, or Summary Binding Decision as set forth in this subpart, the Final...

Exploring the success of an integrated primary care partnership: a longitudinal study of collaboration processes.

PubMed

Valentijn, Pim P; Vrijhoef, Hubertus J M; Ruwaard, Dirk; de Bont, Antoinette; Arends, Rosa Y; Bruijnzeels, Marc A

2015-01-22

Forming partnerships is a prominent strategy used to promote integrated service delivery across health and social service systems. Evidence about the collaboration process upon which partnerships evolve has rarely been addressed in an integrated-care setting. This study explores the longitudinal relationship of the collaboration process and the influence on the final perceived success of a partnership in such a setting. The collaboration process through which partnerships evolve is based on a conceptual framework which identifies five themes: shared ambition, interests and mutual gains, relationship dynamics, organisational dynamics and process management. Fifty-nine out of 69 partnerships from a national programme in the Netherlands participated in this survey study. At baseline, 338 steering committee members responded, and they returned 320 questionnaires at follow-up. Multiple-regression-analyses were conducted to explore the relationship between the baseline as well as the change in the collaboration process and the final success of the partnerships. Mutual gains and process management were the most significant baseline predictors for the final success of the partnership. A positive change in the relationship dynamics had a significant effect on the final success of a partnership. Insight into the collaboration process of integrated primary care partnerships offers a potentially powerful way of predicting their success. Our findings underscore the importance of monitoring the collaboration process during the development of the partnerships in order to achieve their full collaborative advantage.

14 CFR 1214.1105 - Final ranking.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Recruitment and Selection Program § 1214.1105 Final ranking. Final rankings will be based on a combination of the selection board's initial evaluations and the results of the interview process. Veteran's...

Solucion de Problemas y Procesos Cognoscitivos (Problem Solving and Cognitive Processes). Publication No. 41.

ERIC Educational Resources Information Center

Rimoldi, Horacio J. A.

The study of problem solving is made through the analysis of the process that leads to the final answer. The type of information obtained through the study of the process is compared with the information obtained by studying the final answer. The experimental technique used permits to identify the sequence of questions (tactics) that subjects ask…

Federal Register Notice for the Mining Waste Exclusion Final Rule, September 1, 1989

EPA Pesticide Factsheets

Final rule responding to a federal Appeals Court directive to narrow the exclusion of solid waste from the extraction, beneficiation, and processing of ores and minerals from regulation as hazardous waste as it applies to mineral processing wastes.

Final Regulatory Determination for Special Wastes From Mineral Processing (Mining Waste Exclusion) - Federal Register Notice, June 13, 1991

EPA Pesticide Factsheets

This action presents the Agency's final regulatory determination required by section 3001(b)(3)(C) of the Resource Conservation and Recovery Act (RCRA) for 20 special wastes from the processing of ores and minerals.

Microstructure evolution and tensile properties of Zr-2.5 wt.% Nb pressure tubes processed from billets with different microstructures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kapoor, K.; Saratchandran, N.; Muralidharan, K.

1999-02-01

Pressurized heavy water reactors (PHWR) use zirconium-base alloys for their low neutron-absorption cross section, good mechanical strength, low irradiation creep, and high corrosion resistance in reactor atmospheres. Starting with identical ingots, billets having different microstructures were obtained by three different processing methods for fabrication of Zr-2.5 wt%Nb pressure tubes., The billets were further processed by hot extrusion and cold Pilger tube reducing to the finished product. Microstructural characterization was done at each stage of processing. The effects of the initial billet microstructure on the intermediate and final microstructure and mechanical property results were determined. It was found that the structuremore » at each stage and the final mechanical properties depend strongly on the initial billet microstructure. The structure at the final stage consists of elongated alpha zirconium grains with a network of metastable beta zirconium phase. Some of this metastable phase transforms into stable beta niobium during thermomechanical processing. Billets with quenched structure resulted in less beta niobium at the final stage. The air cooled billets resulted in a large amount of beta niobium. The tensile properties, especially the percentage elongation, were found to vary for the different methods. Higher percentage elongation was observed for billets having quenched structure. Extrusion and forging did not produce any characteristic differences in the properties. The results were used to select a process flow sheet which yields the desired mechanical properties with suitable microstructure in the final product.« less

K- absorption on two nucleons and ppK- bound state search in the Σ0p final state

NASA Astrophysics Data System (ADS)

Vázquez Doce, O.; Fabbietti, L.; Cargnelli, M.; Curceanu, C.; Marton, J.; Piscicchia, K.; Scordo, A.; Sirghi, D.; Tucakovic, I.; Wycech, S.; Zmeskal, J.; Anastasi, A.; Curciarello, F.; Czerwinski, E.; Krzemien, W.; Mandaglio, G.; Martini, M.; Moskal, P.; Patera, V.; Pérez del Rio, E.; Silarski, M.

2016-07-01

We report the measurement of K- absorption processes in the Σ0p final state and the first exclusive measurement of the two nucleon absorption (2NA) with the KLOE detector. The 2NA process without further interactions is found to be 9% of the sum of all other contributing processes, including absorption on three and more nucleons or 2NA followed by final state interactions with the residual nucleons. We also determine the possible contribution of the ppK- bound state to the Σ0p final state. The yield of ppK- /Kstop- is found to be (0.044 ± 0.009stat-0.005+0.004 syst) ṡ10-2 but its statistical significance based on an F-test is only 1σ.

Study of Natural Fiber Breakage during Composite Processing

NASA Astrophysics Data System (ADS)

Quijano-Solis, Carlos Jafet

Biofiber-thermoplastic composites have gained considerable importance in the last century. To provide mechanical reinforcement to the polymer, fibers must be larger than a critical aspect ratio (length-to-width ratio). However, biofibers undergo breakage in length or width during processing, affecting their final aspect ratio in the composites. In this study, influence on biofiber breakage by factors related to processing conditions, fiber morphology and the flow type was investigated through: a) experiments using an internal mixer, a twin-screw extruder (TSE) or a capillary rheometer; and b) a Monte Carlo computer simulation. Composites of thermomechanical fibers of aspen or wheat straw mixed with polypropylene were studied. Internal mixer experiments analyzed wheat straw and two batches of aspen fibers, named AL and AS. AL fibers had longer average length. Processing variables included the temperature, rotors speed and fiber concentration. TSE experiments studied AL and AS fiber composites under various screws speeds, temperatures and feeding rates of the polymer and fibers. Capillary rheometers experiments determined AL fiber breakage in shear and elongational flows for composites processed at different concentrations, temperatures, and strain rates. Finally, the internal mixer experimental results where compared to Monte Carlo simulation predictions. The simulation focused on fiber length breakage due to fiber-polymer interactions. Internal mixer results showed that final fiber average length depended almost solely on processing conditions while final fiber average width depended on both processing conditions and initial fiber morphology. In the TSE, processing conditions as well as initial fiber length influenced final average length. TSE results showed that the fiber concentration regime seems to influence the effect of processing variables on fiber breakage. Capillary rheometer experiments demonstrated that biofiber breakage happens in both elongational and shear flows. In some cases, percentage of biofiber breakage in elongational flow is higher. In general, simulation predictions of final average lengths were in good agreement with experiments, indicating the importance of fiber-polymer interactions on fiber breakage. The largest discrepancies were obtained at higher fiber concentration composites; these differences might be resolved, in future simulations, by including the effect of fiber-fiber interactions.

40 CFR 463.2 - General definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... final plastic product. It includes water used in both the detergent wash and rinse cycles of a cleaning... blended, molded, formed, or otherwise processed into intermediate or final products. (b) “Process water” is any raw, service, recycled, or reused water that contacts the plastic product or contacts shaping...

40 CFR 463.2 - General definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... final plastic product. It includes water used in both the detergent wash and rinse cycles of a cleaning... blended, molded, formed, or otherwise processed into intermediate or final products. (b) “Process water” is any raw, service, recycled, or reused water that contacts the plastic product or contacts shaping...

40 CFR 463.2 - General definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... final plastic product. It includes water used in both the detergent wash and rinse cycles of a cleaning... blended, molded, formed, or otherwise processed into intermediate or final products. (b) “Process water” is any raw, service, recycled, or reused water that contacts the plastic product or contacts shaping...

21 CFR 640.91 - Processing.

Code of Federal Regulations, 2012 CFR

2012-04-01

... STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Plasma Protein Fraction (Human) § 640.91 Processing. (a) Date... °C or colder. (e) Heat treatment. Heating of the final containers of Plasma Protein Fraction (Human... concentration of the product. (g) Incubation. All final containers of Plasma Protein Fraction (Human) shall be...

21 CFR 640.91 - Processing.

Code of Federal Regulations, 2011 CFR

2011-04-01

... STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Plasma Protein Fraction (Human) § 640.91 Processing. (a) Date... °C or colder. (e) Heat treatment. Heating of the final containers of Plasma Protein Fraction (Human... concentration of the product. (g) Incubation. All final containers of Plasma Protein Fraction (Human) shall be...

21 CFR 640.91 - Processing.

Code of Federal Regulations, 2013 CFR

2013-04-01

... STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Plasma Protein Fraction (Human) § 640.91 Processing. (a) Date... °C or colder. (e) Heat treatment. Heating of the final containers of Plasma Protein Fraction (Human... concentration of the product. (g) Incubation. All final containers of Plasma Protein Fraction (Human) shall be...

21 CFR 640.91 - Processing.

Code of Federal Regulations, 2014 CFR

2014-04-01

... STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Plasma Protein Fraction (Human) § 640.91 Processing. (a) Date... °C or colder. (e) Heat treatment. Heating of the final containers of Plasma Protein Fraction (Human... concentration of the product. (g) Incubation. All final containers of Plasma Protein Fraction (Human) shall be...

10 CFR 950.34 - Final claim determination.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Final claim determination. 950.34 Section 950.34 Energy DEPARTMENT OF ENERGY STANDBY SUPPORT FOR CERTAIN NUCLEAR PLANT DELAYS Dispute Resolution Process § 950.34 Final claim determination. (a) If the parties reach a Final Claim Determination through mediation, or...

10 CFR 950.34 - Final claim determination.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Final claim determination. 950.34 Section 950.34 Energy DEPARTMENT OF ENERGY STANDBY SUPPORT FOR CERTAIN NUCLEAR PLANT DELAYS Dispute Resolution Process § 950.34 Final claim determination. (a) If the parties reach a Final Claim Determination through mediation, or...

Characterization of Listeria monocytogenes isolated from a fresh mixed sausage processing line in Pelotas-RS by PFGE

PubMed Central

von Laer, Ana Eucares; de Lima, Andréia Saldanha; Trindade, Paula dos Santos; Andriguetto, Cristiano; Destro, Maria Teresa; da Silva, Wladimir Padilha

2009-01-01

Listeria monocytogenes is a bacterium capable to adhere to the surfaces of equipment and utensils and subsequently form biofilms. It can to persist in the food processing environmental for extended periods of time being able to contaminate the final product. The aim of this study was to trace the contamination route of L. monocytogenes on a fresh mixed sausage processing line, from raw material to the final product. The isolates obtained were characterized by serotyping and molecular typing by pulsed-field gel electrophoresis (PFGE) using the restriction enzymes ApaI and AscI. L. monocytogenes was detected in 25% of the samples. The samples of raw material were not contaminated, however, the microorganism was detected in 21% of the environmental samples (food contact and non-food contact), 20.8% of the equipments, 20% of the food worker’s hands, 40% of the mass ready to packaging and in all the final products samples, demonstrating that the contamination of final product occurred during the processing and the importance of cross contamination. PFGE yielded 22 pulsotypes wich formed 7 clusters, and serotyping yielded 3 serotypes and 1 serogroup, however, the presence of serotypes 4b and 1/2b in the final product is of great concern for public health. The tracing of contamination showed that some strains are adapted and persisted in the processing environment in this industry. PMID:24031402

Office of Inspector General; Medicare and state health care programs: fraud and abuse; issuance of advisory opinions by the OIG. Final rule.

PubMed

2008-07-17

OIG is adopting in final form, without change, an interim final rule published on March 26, 2008 (73 FR 15937). We received no comments to the interim final rule. The interim final rule revised the process for advisory opinion requestors to submit payments for advisory opinion costs.

Collaboration processes and perceived effectiveness of integrated care projects in primary care: a longitudinal mixed-methods study.

PubMed

Valentijn, Pim P; Ruwaard, Dirk; Vrijhoef, Hubertus J M; de Bont, Antoinette; Arends, Rosa Y; Bruijnzeels, Marc A

2015-10-09

Collaborative partnerships are considered an essential strategy for integrating local disjointed health and social services. Currently, little evidence is available on how integrated care arrangements between professionals and organisations are achieved through the evolution of collaboration processes over time. The first aim was to develop a typology of integrated care projects (ICPs) based on the final degree of integration as perceived by multiple stakeholders. The second aim was to study how types of integration differ in changes of collaboration processes over time and final perceived effectiveness. A longitudinal mixed-methods study design based on two data sources (surveys and interviews) was used to identify the perceived degree of integration and patterns in collaboration among 42 ICPs in primary care in The Netherlands. We used cluster analysis to identify distinct subgroups of ICPs based on the final perceived degree of integration from a professional, organisational and system perspective. With the use of ANOVAs, the subgroups were contrasted based on: 1) changes in collaboration processes over time (shared ambition, interests and mutual gains, relationship dynamics, organisational dynamics and process management) and 2) final perceived effectiveness (i.e. rated success) at the professional, organisational and system levels. The ICPs were classified into three subgroups with: 'United Integration Perspectives (UIP)', 'Disunited Integration Perspectives (DIP)' and 'Professional-oriented Integration Perspectives (PIP)'. ICPs within the UIP subgroup made the strongest increase in trust-based (mutual gains and relationship dynamics) as well as control-based (organisational dynamics and process management) collaboration processes and had the highest overall effectiveness rates. On the other hand, ICPs with the DIP subgroup decreased on collaboration processes and had the lowest overall effectiveness rates. ICPs within the PIP subgroup increased in control-based collaboration processes (organisational dynamics and process management) and had the highest effectiveness rates at the professional level. The differences across the three subgroups in terms of the development of collaboration processes and the final perceived effectiveness provide evidence that united stakeholders' perspectives are achieved through a constructive collaboration process over time. Disunited perspectives at the professional, organisation and system levels can be aligned by both trust-based and control-based collaboration processes.

Final Report on the Audit of the Administration of the Contract Closeout Process at the Defense Contract Management Region, Dallas

DTIC Science & Technology

1990-09-18

This is our final report on the Audit of the Administration of the Contract Closeout Process at the Defense Contract Management Region, Dallas (DCMR... audit was made from January to October 1989. The objectives of the audit were to determine the timeliness of the contract closeout process, the validity...As part of the audit , we also evaluated internal controls over the contract closeout process. As of December 31, 1988, the Contract Administration

Administrative review process for adjudicating initial disability claims. Final rule.

PubMed

2006-03-31

The Social Security Administration is committed to providing the high quality of service the American people expect and deserve. In light of the significant growth in the number of disability claims and the increased complexity of those claims, the need to make substantial changes in our disability determination process has become urgent. We are publishing a final rule that amends our administrative review process for applications for benefits that are based on whether you are disabled under title II of the Social Security Act (the Act), or applications for supplemental security income (SSI) payments that are based on whether you are disabled or blind under title XVI of the Act. We expect that this final rule will improve the accuracy, consistency, and timeliness of decision-making throughout the disability determination process.

SPIN CORRELATIONS OF THE FINAL LEPTONS IN THE TWO-PHOTON PROCESSES γγ → e+e-, μ+μ-, τ+τ-

NASA Astrophysics Data System (ADS)

Lyuboshitz, Valery V.; Lyuboshitz, Vladimir L.

2014-12-01

The spin structure of the process γγ → e+e- is theoretically investigated. It is shown that, if the primary photons are unpolarized, the final electron and positron are unpolarized as well but their spins are strongly correlated. For the final (e+e-) system, explicit expressions for the components of the correlation tensor are derived, and the relative fractions of singlet and triplet states are found. It is demonstrated that in the process γγ → e+e- one of the Bell-type incoherence inequalities for the correlation tensor components is always violated and, thus, spin correlations of the electron and positron in this process have the strongly pronounced quantum character. Analogous consideration can be wholly applied as well to the two-photon processes γγ → μ+μ- and γγ → τ+τ-, which become possible at considerably higher energies.

77 FR 14473 - Final Guidance on Improving the Process for Preparing Efficient and Timely Environmental Reviews...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-12

... COUNCIL ON ENVIRONMENTAL QUALITY 40 CFR Parts 1500, 1501, 1502, 1503, 1505, 1506, 1507, and 1508 Final Guidance on Improving the Process for Preparing Efficient and Timely Environmental Reviews Under the National Environmental Policy Act AGENCY: Council on Environmental Quality. ACTION: Notice of...

Final STS-11 (41-B) best estimate trajectory products: Development and results from the first Cape landing

NASA Technical Reports Server (NTRS)

Kelly, G. M.; Mcconnell, J. G.; Findlay, J. T.; Heck, M. L.; Henry, M. W.

1984-01-01

The STS-11 (41-B) postflight data processing is completed and the results published. The final reconstructed entry trajectory is presented. The various atmospheric sources available for this flight are discussed. Aerodynamic Best Estimate of Trajectory BET generation and plots from this file are presented. A definition of the major maneuvers effected is given. Physical constants, including spacecraft mass properties; final residuals from the reconstruction process; trajectory parameter listings; and an archival section are included.

37 CFR 104.42 - Finality of settlement or denial of claims.

Code of Federal Regulations, 2010 CFR

2010-07-01

... TRADEMARK OFFICE, DEPARTMENT OF COMMERCE ADMINISTRATION LEGAL PROCESSES Tort Claims § 104.42 Finality of... or denial of any claim under this subpart may be considered final for the purpose of judicial review. ...

Potential sources of variation that influence the final moisture content of kiln-dried hardwood lumber

Treesearch

Hongmei Gu; Timothy M. Young; William W. Moschler; Brian H. Bond

2004-01-01

Excessive variability in the final moisture content (MC) of hardwood lumber may have a significant impact on secondary wood processing and final product performance. Sources of final MC variation during kiln- drying have been studied in prior research. A test examining the final MC of red oak (Quercus spp.) and yellow-poplar (Liriodendron tulipifera) lumber after kiln-...

20 CFR 30.316 - How does the FAB issue a final decision on a claim?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false How does the FAB issue a final decision on a... Adjudicatory Process Hearings and Final Decisions on Claims § 30.316 How does the FAB issue a final decision on... waives any objections to all or part of the recommended decision, the FAB may issue a final decision...

Interaction Between Syntactic Structure and Information Structure in the Processing of a Head-Final Language.

PubMed

Koizumi, Masatoshi; Imamura, Satoshi

2017-02-01

The effects of syntactic and information structures on sentence processing load were investigated using two reading comprehension experiments in Japanese, a head-final SOV language. In the first experiment, we discovered the main effects of syntactic and information structures, as well as their interaction, showing that interaction of these two factors is not restricted to head-initial languages. The second experiment revealed that the interaction between syntactic structure and information structure occurs at the second NP (O of SOV and S of OSV), which, crucially, is a pre-head position, suggesting the incremental nature of the processing of both syntactic structure and information structure in head-final languages.

Biomass ash reutilisation as an additive in the composting process of organic fraction of municipal solid waste.

PubMed

Asquer, Carla; Cappai, Giovanna; De Gioannis, Giorgia; Muntoni, Aldo; Piredda, Martina; Spiga, Daniela

2017-11-01

In this work the effects of selected types of biomass ash on the composting process and final product quality were studied by conducting a 96-day long experiment where the source separated organic fraction of municipal waste, mixed with wood prunings that served as bulking agent, was added with 0%, 2%, 4% and 8% wt/wt of biomass ash. The evolution over time of the main process parameters was observed, and the final composts were characterised. On the basis of the results, both the composting process and the quality of the final product were improved by ash addition. Enhanced volatile solids reduction and biological stability (up to 32% and 52%, respectively, as compared to the unamended product) were attained when ash was added, since ash favored the aerobic degradation by acting asa physical conditioner. In the final products, higher humification of organic matter (expressed in terms of the humification index, that was 2.25 times higher in the most-enriched compost than in the unamended one) and total Ca, K, Mg and P content were observed when ash was used. The latter aspect may influence the composts marketability positively, particularly with regards to potassium and phosphorus. The heavy metals content, that is regarded as the main environmental disadvantage when using ash asa composting additive, did not negatively affect the final composts quality. However, some other controversial effects of ash, related to the moisture and temperature values attained during the process, pH (8.8-9.2 as compared to 8.2 of the unamended compost) and electrical conductivity levels (up to 53% higher as compared to the unamended compost) in the final composts, were also observed. Copyright © 2017 Elsevier Ltd. All rights reserved.

Digital-Computer Processing of Graphical Data. Final Report.

ERIC Educational Resources Information Center

Freeman, Herbert

The final report of a two-year study concerned with the digital-computer processing of graphical data. Five separate investigations carried out under this study are described briefly, and a detailed bibliography, complete with abstracts, is included in which are listed the technical papers and reports published during the period of this program.…

Mixing processes following the final stratospheric warming

NASA Technical Reports Server (NTRS)

Hess, Peter G.

1991-01-01

An investigation is made of the dynamics responsible for the mixing and dissolution of the polar vortex during the final stratospheric warmings. The dynamics and transport during a Northern Hemisphere final stratospheric warming are simulated via a GCM and an associated offline N2O transport model. The results are compared with those obtained from LIMS data for the final warming of 1979, with emphasis on the potential vorticity evolution in the two datasets, the modeled N2O evolution, and the observed O3 evolution. Following each warming, the remnants of the originally intact vortex are found to gradually homogenize with the atmosphere at large. Two processes leading to this homogenization are identified following the final warmings, namely, the potential vorticity field becomes decorrelated from that of the chemical tracer, and the vortex remnants begin to tilt dramatically in a vertical direction.

A review of pharmaceutical extrusion: critical process parameters and scaling-up.

PubMed

Thiry, J; Krier, F; Evrard, B

2015-02-01

Hot melt extrusion has been a widely used process in the pharmaceutical area for three decades. In this field, it is important to optimize the formulation in order to meet specific requirements. However, the process parameters of the extruder should be as much investigated as the formulation since they have a major impact on the final product characteristics. Moreover, a design space should be defined in order to obtain the expected product within the defined limits. This gives some freedom to operate as long as the processing parameters stay within the limits of the design space. Those limits can be investigated by varying randomly the process parameters but it is recommended to use design of experiments. An examination of the literature is reported in this review to summarize the impact of the variation of the process parameters on the final product properties. Indeed, the homogeneity of the mixing, the state of the drug (crystalline or amorphous), the dissolution rate, the residence time, can be influenced by variations in the process parameters. In particular, the impact of the following process parameters: temperature, screw design, screw speed and feeding, on the final product, has been reviewed. Copyright © 2014 Elsevier B.V. All rights reserved.

Interaction between Syntactic Structure and Information Structure in the Processing of a Head-Final Language

ERIC Educational Resources Information Center

Koizumi, Masatoshi; Imamura, Satoshi

2017-01-01

The effects of syntactic and information structures on sentence processing load were investigated using two reading comprehension experiments in Japanese, a head-final SOV language. In the first experiment, we discovered the main effects of syntactic and information structures, as well as their interaction, showing that interaction of these two…

30 CFR 1206.363 - When is an ONRR audit, review, reconciliation, monitoring, or other like process considered final?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 3 2012-07-01 2012-07-01 false When is an ONRR audit, review, reconciliation, monitoring, or other like process considered final? 1206.363 Section 1206.363 Mineral Resources OFFICE OF NATURAL RESOURCES REVENUE, DEPARTMENT OF THE INTERIOR NATURAL RESOURCES REVENUE PRODUCT VALUATION...

30 CFR 1206.363 - When is an ONRR audit, review, reconciliation, monitoring, or other like process considered final?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 3 2013-07-01 2013-07-01 false When is an ONRR audit, review, reconciliation, monitoring, or other like process considered final? 1206.363 Section 1206.363 Mineral Resources OFFICE OF NATURAL RESOURCES REVENUE, DEPARTMENT OF THE INTERIOR NATURAL RESOURCES REVENUE PRODUCT VALUATION...

30 CFR 1206.363 - When is an ONRR audit, review, reconciliation, monitoring, or other like process considered final?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 3 2014-07-01 2014-07-01 false When is an ONRR audit, review, reconciliation, monitoring, or other like process considered final? 1206.363 Section 1206.363 Mineral Resources OFFICE OF NATURAL RESOURCES REVENUE, DEPARTMENT OF THE INTERIOR NATURAL RESOURCES REVENUE PRODUCT VALUATION...

Interactions of Science and Technology in the Innovative Process: Some Case Studies. Final Report.

ERIC Educational Resources Information Center

Battelle Memorial Inst., Columbus, OH. Columbus Labs.

This is the final report of the latest effort in a series sponsored by the National Science Foundation on the innovation process. It adds to the store of retrospective case studies by documenting historically the significant events in several technological innovations of high social impact. These cases, drawn together by the Battelle Columbus…

Perceptual Processing of Mandarin Nasals by L1 and L2 Mandarin Speakers

ERIC Educational Resources Information Center

Lai, Yi-hsiu

2012-01-01

Nasals are cross-linguistically susceptible to change, especially in the syllable final position. Acoustic reports on Mandarin nasal production have recently shown that the syllable-final distinction is frequently dropped. Few studies, however, have addressed the issue of perceptual processing in Mandarin nasals for L1 and L2 speakers of Mandarin…

76 FR 72172 - Continuation of Antidumping Duty Order: Pure Magnesium From the People's Republic of China

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-22

... Canada by Timminco, Ltd. from pure magnesium of Chinese origin are not within the scope of order. See Memorandum regarding Final Ruling in the Scope Inquiry on Russian and Chinese Magnesium Processed in Canada... Memorandum regarding Final Ruling in the Scope Inquiry on Chinese Magnesium Processed in France, dated...

Occurrence of Antimicrobial-Resistant Escherichia coli and Salmonella enterica in the Beef Cattle Production and Processing Continuum

PubMed Central

Agga, Getahun E.; Bosilevac, Joseph M.; Brichta-Harhay, Dayna M.; Shackelford, Steven D.; Wang, Rong; Wheeler, Tommy L.; Arthur, Terrance M.

2014-01-01

Specific concerns have been raised that third-generation cephalosporin-resistant (3GCr) Escherichia coli, trimethoprim-sulfamethoxazole-resistant (COTr) E. coli, 3GCr Salmonella enterica, and nalidixic acid-resistant (NALr) S. enterica may be present in cattle production environments, persist through beef processing, and contaminate final products. The prevalences and concentrations of these organisms were determined in feces and hides (at feedlot and processing plant), pre-evisceration carcasses, and final carcasses from three lots of fed cattle (n = 184). The prevalences and concentrations were further determined for strip loins from 103 of the carcasses. 3GCr Salmonella was detected on 7.6% of hides during processing and was not detected on the final carcasses or strip loins. NALr S. enterica was detected on only one hide. 3GCr E. coli and COTr E. coli were detected on 100.0% of hides during processing. Concentrations of 3GCr E. coli and COTr E. coli on hides were correlated with pre-evisceration carcass contamination. 3GCr E. coli and COTr E. coli were each detected on only 0.5% of final carcasses and were not detected on strip loins. Five hundred and 42 isolates were screened for extraintestinal pathogenic E. coli (ExPEC) virulence-associated markers. Only two COTr E. coli isolates from hides were ExPEC, indicating that fed cattle products are not a significant source of ExPEC causing human urinary tract infections. The very low prevalences of these organisms on final carcasses and their absence on strip loins demonstrate that current sanitary dressing procedures and processing interventions are effective against antimicrobial-resistant bacteria. PMID:25398858

Occurrence of Antimicrobial-Resistant Escherichia coli and Salmonella enterica in the Beef Cattle Production and Processing Continuum.

PubMed

Schmidt, John W; Agga, Getahun E; Bosilevac, Joseph M; Brichta-Harhay, Dayna M; Shackelford, Steven D; Wang, Rong; Wheeler, Tommy L; Arthur, Terrance M

2015-01-01

Specific concerns have been raised that third-generation cephalosporin-resistant (3GC(r)) Escherichia coli, trimethoprim-sulfamethoxazole-resistant (COT(r)) E. coli, 3GC(r) Salmonella enterica, and nalidixic acid-resistant (NAL(r)) S. enterica may be present in cattle production environments, persist through beef processing, and contaminate final products. The prevalences and concentrations of these organisms were determined in feces and hides (at feedlot and processing plant), pre-evisceration carcasses, and final carcasses from three lots of fed cattle (n = 184). The prevalences and concentrations were further determined for strip loins from 103 of the carcasses. 3GC(r) Salmonella was detected on 7.6% of hides during processing and was not detected on the final carcasses or strip loins. NAL(r) S. enterica was detected on only one hide. 3GC(r) E. coli and COT(r) E. coli were detected on 100.0% of hides during processing. Concentrations of 3GC(r) E. coli and COT(r) E. coli on hides were correlated with pre-evisceration carcass contamination. 3GC(r) E. coli and COT(r) E. coli were each detected on only 0.5% of final carcasses and were not detected on strip loins. Five hundred and 42 isolates were screened for extraintestinal pathogenic E. coli (ExPEC) virulence-associated markers. Only two COT(r) E. coli isolates from hides were ExPEC, indicating that fed cattle products are not a significant source of ExPEC causing human urinary tract infections. The very low prevalences of these organisms on final carcasses and their absence on strip loins demonstrate that current sanitary dressing procedures and processing interventions are effective against antimicrobial-resistant bacteria. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Hoyoung; Korea Institute of Materials Science, 797 Changwon-daero, Seongsan-gu, Changwon, Gyeongnam 642-831; Kang, Jun-Yun, E-mail: firice@kims.re.kr

This study aimed to present the complete history of carbide evolution in a cold-work tool steel along its full processing route for fabrication and application. A sequence of processes from cast to final hardening heat treatment was conducted on an 8% Cr-steel to reproduce a typical commercial processing route in a small scale. The carbides found at each process step were then identified by electron diffraction with energy dispersive spectroscopy in a scanning or transmission electron microscope. After solidification, MC, M{sub 7}C{sub 3} and M{sub 2}C carbides were identified and the last one dissolved during hot compression at 1180 °C.more » In a subsequent annealing at 870 °C followed by slow cooling, M{sub 6}C and M{sub 23}C{sub 6} were added, while they were dissolved in the following austenitization at 1030 °C. After the final tempering at 520 °C, fine M{sub 23}C{sub 6} precipitated again, thus the final microstructure was the tempered martensite with MC, M{sub 7}C{sub 3} and M{sub 23}C{sub 6} carbide. The transient M{sub 2}C and M{sub 6}C originated from the segregation of Mo and finally disappeared due to attenuated segregation and the consequent thermodynamic instability. - Highlights: • The full processing route of a cold-work tool steel was simulated in a small scale. • The carbides in the tool steel were identified by chemical–crystallographic analyses. • MC, M{sub 7}C{sub 3}, M{sub 2}C, M{sub 6}C and M{sub 23}C{sub 6} carbides were found during the processing of the steel. • M{sub 2}C and M{sub 6}C finally disappeared due to thermodynamic instability.« less

24 CFR 58.60 - Preparation and filing of environmental impact statements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... ENVIRONMENTAL RESPONSIBILITIES Environmental Review Process: Procedures for Draft, Final and Supplemental... responsible entity must prepare the draft environmental impact statement (DEIS) and the final environmental... may request waivers from the time requirements specified for the draft and final EIS as prescribed in...

24 CFR 58.60 - Preparation and filing of environmental impact statements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... ENVIRONMENTAL RESPONSIBILITIES Environmental Review Process: Procedures for Draft, Final and Supplemental... responsible entity must prepare the draft environmental impact statement (DEIS) and the final environmental... may request waivers from the time requirements specified for the draft and final EIS as prescribed in...

24 CFR 58.60 - Preparation and filing of environmental impact statements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... ENVIRONMENTAL RESPONSIBILITIES Environmental Review Process: Procedures for Draft, Final and Supplemental... responsible entity must prepare the draft environmental impact statement (DEIS) and the final environmental... may request waivers from the time requirements specified for the draft and final EIS as prescribed in...

24 CFR 58.60 - Preparation and filing of environmental impact statements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... ENVIRONMENTAL RESPONSIBILITIES Environmental Review Process: Procedures for Draft, Final and Supplemental... responsible entity must prepare the draft environmental impact statement (DEIS) and the final environmental... may request waivers from the time requirements specified for the draft and final EIS as prescribed in...

Patterning control strategies for minimum edge placement error in logic devices

NASA Astrophysics Data System (ADS)

Mulkens, Jan; Hanna, Michael; Slachter, Bram; Tel, Wim; Kubis, Michael; Maslow, Mark; Spence, Chris; Timoshkov, Vadim

2017-03-01

In this paper we discuss the edge placement error (EPE) for multi-patterning semiconductor manufacturing. In a multi-patterning scheme the creation of the final pattern is the result of a sequence of lithography and etching steps, and consequently the contour of the final pattern contains error sources of the different process steps. We describe the fidelity of the final pattern in terms of EPE, which is defined as the relative displacement of the edges of two features from their intended target position. We discuss our holistic patterning optimization approach to understand and minimize the EPE of the final pattern. As an experimental test vehicle we use the 7-nm logic device patterning process flow as developed by IMEC. This patterning process is based on Self-Aligned-Quadruple-Patterning (SAQP) using ArF lithography, combined with line cut exposures using EUV lithography. The computational metrology method to determine EPE is explained. It will be shown that ArF to EUV overlay, CDU from the individual process steps, and local CD and placement of the individual pattern features, are the important contributors. Based on the error budget, we developed an optimization strategy for each individual step and for the final pattern. Solutions include overlay and CD metrology based on angle resolved scatterometry, scanner actuator control to enable high order overlay corrections and computational lithography optimization to minimize imaging induced pattern placement errors of devices and metrology targets.

Commercially sterilized mussel meats (Mytilus chilensis): a study on process yield.

PubMed

Almonacid, S; Bustamante, J; Simpson, R; Urtubia, A; Pinto, M; Teixeira, A

2012-06-01

The processing steps most responsible for yield loss in the manufacture of canned mussel meats are the thermal treatments of precooking to remove meats from shells, and thermal processing (retorting) to render the final canned product commercially sterile for long-term shelf stability. The objective of this study was to investigate and evaluate the impact of different combinations of process variables on the ultimate drained weight in the final mussel product (Mytilu chilensis), while verifying that any differences found were statistically and economically significant. The process variables selected for this study were precooking time, brine salt concentration, and retort temperature. Results indicated 2 combinations of process variables producing the widest difference in final drained weight, designated best combination and worst combination with 35% and 29% yield, respectively. Significance of this difference was determined by employing a Bootstrap methodology, which assumes an empirical distribution of statistical error. A difference of nearly 6 percentage points in total yield was found. This represents a 20% increase in annual sales from the same quantity of raw material, in addition to increase in yield, the conditions for the best process included a retort process time 65% shorter than that for the worst process, this difference in yield could have significant economic impact, important to the mussel canning industry. © 2012 Institute of Food Technologists®

Final Report for Contract N00014-89-J-1967 for the Time Period from 1 May 1989 to 31 December 1990 (Texas Univ. at Austin. Applied Research Labs.)

DTIC Science & Technology

1991-04-23

in this section. In our investigation of higher order processing methods for remote acoustic sensing we sought to understand the principles of laser...magnitude less than those presently detected in laboratory measurements. An initial study of several potential higher order processing techniques was...incoherent. The use of higher order processing methods to provide some level of discrimination against noise thus appears tractable. Finally, the effects

Overcoming pitfalls: Results from a mandatory peer review process for written examinations.

PubMed

Wilby, Kyle John; El Hajj, Maguy S; El-Bashir, Marwa; Mraiche, Fatima

2018-04-01

Written assessments are essential components of higher education practices. However, faculty members encounter common pitfalls when designing questions intended to evaluate student-learning outcomes. The objective of this project was to determine the impact of a mandatory examination peer review process on question accuracy, alignment with learning objectives, use of best practices in question design, and language/grammar. A mandatory peer review process was implemented for all midterm (before phase) and final (after phase) examinations. Peer review occurred by two reviewers and followed a pre-defined guidance document. Non-punitive feedback given to faculty members served as the intervention. Frequencies of flagged questions according to guidance categories were compared between phases. A total of 21 midterm and 21 final exam reviews were included in the analysis. A total of 637 questions were reviewed across all midterms and 1003 questions were reviewed across all finals. Few questions were flagged for accuracy and alignment with learning outcomes. The median total proportion of questions flagged for best practices was significantly lower for final exams versus midterm exams (15.8 vs. 6.45%, p = 0.014). The intervention did not influence language and grammar errors (9.68 vs. 10.0% of questions flagged before and after, respectively, p = 0.305). A non-punitive peer review process for written examinations can overcome pitfalls in exam creation and improve best practices in question writing. The peer-review process had a substantial effect at flagging language/grammar errors but error rate did not differ between midterm and final exams. Copyright © 2017 Elsevier Inc. All rights reserved.

Bicultural Socialization Project: A Group Process Approach to Bilingual Instruction - Title VII. Final Report, 1970-71.

ERIC Educational Resources Information Center

Baker, Jean M.

This final report relates to student socialization through a bilingual (Spanish/English), bicultural program involving 6 second grades in 3 schools of Phoenix, Arizona, for the 1970-71 school year. As reported, the major objective of the program was to develop and implement a group process approach to bilingual education; in addition, classroom…

Levels of Possession of Science Process Skills by Final Year Students of Colleges of Education in South-Eastern States of Nigeria

ERIC Educational Resources Information Center

Akani, Omiko

2015-01-01

This study investigated the levels of possession of science process skills by final year Nigerian Certificate in Education (NCE) Students in colleges of Education in South-Eastern States of Nigeria. The skills that were assessed were observation, experimentation, measurement, communication, and inference. The research was guided by five research…

A new intuitionistic fuzzy rule-based decision-making system for an operating system process scheduler.

PubMed

Butt, Muhammad Arif; Akram, Muhammad

2016-01-01

We present a new intuitionistic fuzzy rule-based decision-making system based on intuitionistic fuzzy sets for a process scheduler of a batch operating system. Our proposed intuitionistic fuzzy scheduling algorithm, inputs the nice value and burst time of all available processes in the ready queue, intuitionistically fuzzify the input values, triggers appropriate rules of our intuitionistic fuzzy inference engine and finally calculates the dynamic priority (dp) of all the processes in the ready queue. Once the dp of every process is calculated the ready queue is sorted in decreasing order of dp of every process. The process with maximum dp value is sent to the central processing unit for execution. Finally, we show complete working of our algorithm on two different data sets and give comparisons with some standard non-preemptive process schedulers.

Electronic propensity rules in Li-H+ collisions involving initial and/or final oriented states

NASA Astrophysics Data System (ADS)

Salas, P. J.

2000-12-01

Electronic excitation and capture processes are studied in collisions involving systems with only one active electron such as the alkaline (Li)-proton in the medium-energy region (0.1-15 keV). Using the semiclassical impact parameter method, the probabilities and the orientation parameter are calculated for transitions between initial and/or final oriented states. The results show a strong asymmetry in the probabilities depending on the orientation of the initial and/or final states. An intuitive view of the processes, by means of the concepts of propensity and velocity matching rules, is provided.

20 CFR 405.372 - Finality of an administrative law judge's decision.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Finality of an administrative law judge's decision. 405.372 Section 405.372 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ADMINISTRATIVE REVIEW PROCESS FOR ADJUDICATING INITIAL DISABILITY CLAIMS Administrative Law Judge Hearing § 405.372 Finality of...

A Comparison of American Indian and Non-American Indian Parental Involvement in the IEP Process: Perceived Needs for Involvement and Training. Final Report.

ERIC Educational Resources Information Center

Gajar, Anna; Matuszny, Rose Marie

This final report discusses the activities and outcomes of a study that investigated the involvement of American Indian/Alaska Native (AI/AN) and non-American Indian/Alaska Native parents of children with disabilities in the general educational and Individualized Education Program (IEP) processes, and the specific needs of parents that would…

Data-driven monitoring for stochastic systems and its application on batch process

NASA Astrophysics Data System (ADS)

Yin, Shen; Ding, Steven X.; Haghani Abandan Sari, Adel; Hao, Haiyang

2013-07-01

Batch processes are characterised by a prescribed processing of raw materials into final products for a finite duration and play an important role in many industrial sectors due to the low-volume and high-value products. Process dynamics and stochastic disturbances are inherent characteristics of batch processes, which cause monitoring of batch processes a challenging problem in practice. To solve this problem, a subspace-aided data-driven approach is presented in this article for batch process monitoring. The advantages of the proposed approach lie in its simple form and its abilities to deal with stochastic disturbances and process dynamics existing in the process. The kernel density estimation, which serves as a non-parametric way of estimating the probability density function, is utilised for threshold calculation. An industrial benchmark of fed-batch penicillin production is finally utilised to verify the effectiveness of the proposed approach.

Molding cork sheets to complex shapes

NASA Technical Reports Server (NTRS)

Sharpe, M. H.; Simpson, W. G.; Walker, H. M.

1977-01-01

Partially cured cork sheet is easily formed to complex shapes and then final-cured. Temperature and pressure levels required for process depend upon resin system used and final density and strength desired. Sheet can be bonded to surface during final cure, or can be first-formed in mold and bonded to surface in separate step.

77 FR 44267 - Notice of Availability of the Final Programmatic Environmental Impact Statement for Solar Energy...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-27

... Final EIS NOA and use them to inform the Records of Decision. Those individuals wishing to submit... general information regarding the DOE NEPA process, contact Carol Borgstrom, Director, Office of NEPA... development. Through the Final Programmatic EIS, the BLM is considering replacing elements of its existing...

Yield strength mapping in the cross section of ERW pipes considering kinematic hardening and residual stress

NASA Astrophysics Data System (ADS)

Kim, Dongwook; Quagliato, Luca; Lee, Wontaek; Kim, Naksoo

2017-09-01

In the ERW (electric resistance welding) pipe manufacturing, material properties, process conditions and settings strongly influences the mechanical performances of the final product, as well as they can make them to be not uniform and to change from point to point in the pipe. The present research work proposes an integrated numerical model for the study of the whole ERW process, considering roll forming, welding and sizing stations, allowing to infer the influence of the process parameters on the final quality of the pipe, in terms of final shape and residual stress. The developed numerical model has been initially validated comparing the dimensions of the pipe derived from the simulation results with those of industrial production, proving the reliability of the approach. Afterwards, by varying the process parameters in the numerical simulation, namely the roll speed, the sizing ratio and the friction factor, the influence on the residual stress in the pipe, at the end of the process and after each station, is studied and discussed along the paper.

High performance low cost interconnections for flip chip attachment with electrically conductive adhesive. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-05-01

This final report is a compilation of final reports from each of the groups participating in the program. The main three groups involved in this effort are the Thomas J. Watson Research Center of IBM Corporation in Yorktown Heights, New York, Assembly Process Design of IBM Corporation in Endicott, New York, and SMT Laboratory of Universal Instruments Corporation in Binghamton, New York. The group at the research center focused on the conductive adhesive materials development and characterization. The group in process development focused on processing of the Polymer-Metal-Solvent Paste (PMSP) to form conductive adhesive bumps, formation of the Polymer-Metal Compositemore » (PMC) on semiconductor devices and study of the bonding process to circuitized organic carriers, and the long term durability and reliability of joints formed using the process. The group at Universal Instruments focused on development of an equipment set and bonding parameters for the equipment to produce bond assembly tooling. Reports of each of these individual groups are presented here reviewing their technical efforts and achievements.« less

Pyrolysis of tyres. Influence of the final temperature of the process on emissions and the calorific value of the products recovered.

PubMed

Díez, C; Martínez, O; Calvo, L F; Cara, J; Morán, A

2004-01-01

A study was made of the pyrolysis of tyre particles, with the aim of determining the possibilities of using the products resulting from the process as fuel. Three final temperatures were used, determined from thermogravimetric data. The design of the experiment was a horizontal oven containing a reactor into which particles of the original tyre were placed. After the process, a solid fraction (char) remained in the reactor, while the gases generated went through a set of scrubbers where most of the condensable fraction (oils) was retained. Finally, once free of this fraction, the gases were collected in glass ampoules. Solid and liquids fractions were subjected to thermogravimetric analyses in order to study their combustibility. The gas fraction was analysed by means of gas chromatography to establish the content of CO, CO2, H2 and hydrocarbons present in the samples (mainly components of gases produced in the pyrolysis process). A special study was made of the sulphur and chlorine content of all the fractions, as the presence of these elements could be problematic if the products are used as fuel. Tyre pyrolysis engenders a solid carbon residue that concentrates sulphur and chorine, with a relatively high calorific value, although not so high as that of the original tyre. The liquid fraction produced by the process has a high calorific value, which rises with the final temperature, up to 40 MJ/kg. The chlorine content of this fraction is negligible. Over 95% of the gas fraction, regardless of the final temperature, is composed of hydrocarbons of a low molecular weight and hydrogen, this fraction also appearing to be free of chlorine.

Waveguide Studies for Fiber Optics and Optical Signal Processing Applications.

DTIC Science & Technology

1980-04-01

AO-A086 115 UNI!VERtSIT? OF SOUTIUR CALEPCRNA LOS AMUSS / 5 WAVGUIDE STUIES15 FOR FEB53 OpTECS AND OpTICAL SEOSA.o P /0Ksu-y "/6 UNLSIIDAPR N0 E...SAMUE Flola-??-c-sa UNCASZFIORAC-M-8042 U Final Technical Report (1 1April 1950 L V ~ WAVEGUIDE STUDIES FOR FIBER OPTICS AND OPTICAL SIGNAL PROCESSING...and Subtitle) 081 6&4𔃾JODO )EI YAVECUIDESTUDIES FOR JIBER OPTICS ANDL 7 Final ,T/echnical epoErt, OPTICAL SI’tNAL PROCESSING APPLICATIONS.4 11 Se 77

Event-Based Processing of Neutron Scattering Data

DOE PAGES

Peterson, Peter F.; Campbell, Stuart I.; Reuter, Michael A.; ...

2015-09-16

Many of the world's time-of-flight spallation neutrons sources are migrating to the recording of individual neutron events. This provides for new opportunities in data processing, the least of which is to filter the events based on correlating them with logs of sample environment and other ancillary equipment. This paper will describe techniques for processing neutron scattering data acquired in event mode that preserve event information all the way to a final spectrum, including any necessary corrections or normalizations. This results in smaller final errors, while significantly reducing processing time and memory requirements in typical experiments. Results with traditional histogramming techniquesmore » will be shown for comparison.« less

Computer modeling of dynamic necking in bars

NASA Astrophysics Data System (ADS)

Partom, Yehuda; Lindenfeld, Avishay

2017-06-01

Necking of thin bodies (bars, plates, shells) is one form of strain localization in ductile materials that may lead to fracture. The phenomenon of necking has been studied extensively, initially for quasistatic loading and then also for dynamic loading. Nevertheless, many issues concerning necking are still unclear. Among these are: 1) is necking a random or deterministic process; 2) how does the specimen choose the final neck location; 3) to what extent do perturbations (material or geometrical) influence the neck forming process; and 4) how do various parameters (material, geometrical, loading) influence the neck forming process. Here we address these issues and others using computer simulations with a hydrocode. Among other things we find that: 1) neck formation is a deterministic process, and by changing one of the parameters influencing it monotonously, the final neck location moves monotonously as well; 2) the final neck location is sensitive to the radial velocity of the end boundaries, and as motion of these boundaries is not fully controlled in tests, this may be the reason why neck formation is sometimes regarded as a random process; and 3) neck formation is insensitive to small perturbations, which is probably why it is a deterministic process.

CAPACITY BUILDING PROCESS IN ENVIRONMENTAL AND HEALTH IMPACT ASSESSMENT FOR A THAI COMMUNITY.

PubMed

Chaithui, Suthat; Sithisarankul, Pornchai; Hengpraprom, Sarunya

2017-03-01

This research aimed at exploring the development of the capacitybuilding process in environmental and health impact assessment, including the consideration of subsequent, capacity-building achievements. Data were gathered through questionnaires, participatory observations, in-depth interviews, focus group discussions, and capacity building checklist forms. These data were analyzed using content analysis, descriptive statistics, and inferential statistics. Our study used the components of the final draft for capacity-building processes consisting of ten steps that were formulated by synthesis from each respective process. Additionally, the evaluation of capacity building levels was performed using 10-item evaluation criteria for nine communities. The results indicated that the communities performed well under these criteria. Finally, exploration of the factors influencing capacity building in environmental and health impact assessment indicated that the learning of community members by knowledge exchange via activities and study visits were the most influential factors of the capacity building processes in environmental and health impact assessment. The final revised version of capacitybuilding process in environmental and health impact assessment could serve as a basis for the consideration of interventions in similar areas, so that they increased capacity in environmental and health impact assessments.

The retrovirus RNA trafficking granule: from birth to maturity

PubMed Central

Cochrane, Alan W; McNally, Mark T; Mouland, Andrew J

2006-01-01

Post-transcriptional events in the life of an RNA including RNA processing, transport, translation and metabolism are characterized by the regulated assembly of multiple ribonucleoprotein (RNP) complexes. At each of these steps, there is the engagement and disengagement of RNA-binding proteins until the RNA reaches its final destination. For retroviral genomic RNA, the final destination is the capsid. Numerous studies have provided crucial information about these processes and serve as the basis for studies on the intracellular fate of retroviral RNA. Retroviral RNAs are like cellular mRNAs but their processing is more tightly regulated by multiple cis-acting sequences and the activities of many trans-acting proteins. This review describes the viral and cellular partners that retroviral RNA encounters during its maturation that begins in the nucleus, focusing on important events including splicing, 3' end-processing, RNA trafficking from the nucleus to the cytoplasm and finally, mechanisms that lead to its compartmentalization into progeny virions. PMID:16545126

[Participation of final products of lipid peroxidation in the anticancer mechanism of ionizing radiation and radiomimetic cytostatics].

PubMed

Przybyszewski, W M

2001-01-01

This review reports the evidence for the participation of final products of lipid peroxidation in the anticancer mechanism of ionising radiation and radiomimetic cytostatics. Processes of lipid peroxidation occur endogenously in response to oxidative stress and great diversity of reactive metabolites is formed. However, direct observation of radical reaction in pathophysiology of cells, tissues and organs is limited technically. Most investigations focused on the indirect assessment of their final products, aldehydes. The peroxidative breakdown of polyunsaturated fatty acids is believed to be involved in the regulation of cell division, and antitumor effect through biochemical and genetic processes.

Emissions Inventory Final Rule TSD

EPA Pesticide Factsheets

This technical support document (TSD) provides the details of emissions data processing done in support of EPA's final rulemaking effort for the Federal Transport Rule, now known as the Cross-State Air Pollution Rule.

Recent progress in continuous and semi-continuous processing of solid oral dosage forms: a review.

PubMed

Teżyk, Michał; Milanowski, Bartłomiej; Ernst, Andrzej; Lulek, Janina

2016-08-01

Continuous processing is an innovative production concept well known and successfully used in other industries for many years. The modern pharmaceutical industry is facing the challenge of transition from a traditional manufacturing approach based on batch-wise production to a continuous manufacturing model. The aim of this article is to present technological progress in manufacturing based on continuous and semi-continuous processing of the solid oral dosage forms. Single unit processes possessing an alternative processing pathway to batch-wise technology or, with some modification, an altered approach that may run continuously, and are thus able to seamlessly switch to continuous manufacturing are briefly presented. Furthermore, the concept of semi-continuous processing is discussed. Subsequently, more sophisticated production systems created by coupling single unit processes and comprising all the steps of production, from powder to final dosage form, were reviewed. Finally, attempts of end-to-end production approach, meaning the linking of continuous synthesis of API from intermediates with the production of final dosage form, are described. There are a growing number of scientific articles showing an increasing interest in changing the approach to the production of pharmaceuticals in recent years. Numerous scientific publications are a source of information on the progress of knowledge and achievements of continuous processing. These works often deal with issues of how to modify or replace the unit processes in order to enable seamlessly switching them into continuous processing. A growing number of research papers concentrate on integrated continuous manufacturing lines in which the production concept of "from powder to tablet" is realized. Four main domains are under investigation: influence of process parameters on intermediates or final dosage forms properties, implementation of process analytical tools, control-managing system responsible for keeping continuous materials flow through the whole manufacturing process and the development of new computational methods to assess or simulate these new manufacturing techniques. The attempt to connect the primary and secondary production steps proves that development of continuously operating lines is possible. A mind-set change is needed to be able to face, and fully assess, the advantages and disadvantages of switching from batch to continuous mode production.

What is the Final Verification of Engineering Requirements?

NASA Technical Reports Server (NTRS)

Poole, Eric

2010-01-01

This slide presentation reviews the process of development through the final verification of engineering requirements. The definition of the requirements is driven by basic needs, and should be reviewed by both the supplier and the customer. All involved need to agree upon a formal requirements including changes to the original requirements document. After the requirements have ben developed, the engineering team begins to design the system. The final design is reviewed by other organizations. The final operational system must satisfy the original requirements, though many verifications should be performed during the process. The verification methods that are used are test, inspection, analysis and demonstration. The plan for verification should be created once the system requirements are documented. The plan should include assurances that every requirement is formally verified, that the methods and the responsible organizations are specified, and that the plan is reviewed by all parties. The options of having the engineering team involved in all phases of the development as opposed to having some other organization continue the process once the design has been complete is discussed.

Medicaid Program; Mechanized Claims Processing and Information Retrieval Systems (90/10). Final rule.

PubMed

2015-12-04

This final rule will extend enhanced funding for Medicaid eligibility systems as part of a state's mechanized claims processing system, and will update conditions and standards for such systems, including adding to and updating current Medicaid Management Information Systems (MMIS) conditions and standards. These changes will allow states to improve customer service and support the dynamic nature of Medicaid eligibility, enrollment, and delivery systems.

Canister Storage Building (CSB) Hazard Analysis Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

POWERS, T.B.

2000-03-16

This report describes the methodology used in conducting the Canister Storage Building (CSB) Hazard Analysis to support the final CSB Safety Analysis Report and documents the results. This report describes the methodology used in conducting the Canister Storage Building (CSB) hazard analysis to support the CSB final safety analysis report (FSAR) and documents the results. The hazard analysis process identified hazardous conditions and material-at-risk, determined causes for potential accidents, identified preventive and mitigative features, and qualitatively estimated the frequencies and consequences of specific occurrences. The hazard analysis was performed by a team of cognizant CSB operations and design personnel, safetymore » analysts familiar with the CSB, and technical experts in specialty areas. The material included in this report documents the final state of a nearly two-year long process. Attachment A provides two lists of hazard analysis team members and describes the background and experience of each. The first list is a complete list of the hazard analysis team members that have been involved over the two-year long process. The second list is a subset of the first list and consists of those hazard analysis team members that reviewed and agreed to the final hazard analysis documentation. The material included in this report documents the final state of a nearly two-year long process involving formal facilitated group sessions and independent hazard and accident analysis work. The hazard analysis process led to the selection of candidate accidents for further quantitative analysis. New information relative to the hazards, discovered during the accident analysis, was incorporated into the hazard analysis data in order to compile a complete profile of facility hazards. Through this process, the results of the hazard and accident analyses led directly to the identification of safety structures, systems, and components, technical safety requirements, and other controls required to protect the public, workers, and environment.« less

21 CFR 640.81 - Processing.

Code of Federal Regulations, 2013 CFR

2013-04-01

... product as referred to in § 640.84(d). (g) Incubation. All final containers of Albumin (Human) shall be... this section. At the end of this incubation period, each final container shall be examined and all...

21 CFR 640.81 - Processing.

Code of Federal Regulations, 2012 CFR

2012-04-01

... product as referred to in § 640.84(d). (g) Incubation. All final containers of Albumin (Human) shall be... this section. At the end of this incubation period, each final container shall be examined and all...

21 CFR 640.81 - Processing.

Code of Federal Regulations, 2014 CFR

2014-04-01

... product as referred to in § 640.84(d). (g) Incubation. All final containers of Albumin (Human) shall be... this section. At the end of this incubation period, each final container shall be examined and all...

Medicaid and Children's Health Insurance Programs: Eligibility Notices, Fair Hearing and Appeal Processes for Medicaid and Other Provisions Related to Eligibility and Enrollment for Medicaid and CHIP. Final rule.

PubMed

2016-11-30

This final rule implements provisions of the Affordable Care Act that expand access to health coverage through improvements in Medicaid and coordination between Medicaid, CHIP, and Exchanges. This rule finalizes most of the remaining provisions from the "Medicaid, Children's Health Insurance Programs, and Exchanges: Essential Health Benefits in Alternative Benefit Plans, Eligibility Notices, Fair Hearing and Appeal Processes for Medicaid and Exchange Eligibility Appeals and Other Provisions Related to Eligibility and Enrollment for Exchanges, Medicaid and CHIP, and Medicaid Premiums and Cost Sharing; Proposed Rule" that we published in the January 22, 2013, Federal Register. This final rule continues our efforts to assist states in implementing Medicaid and CHIP eligibility, appeals, and enrollment changes required by the Affordable Care Act.

Final Design Report for the RH LLW Disposal Facility (RDF) Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Austad, Stephanie Lee

2015-09-01

The RH LLW Disposal Facility (RDF) Project was designed by AREVA Federal Services (AFS) and the design process was managed by Battelle Energy Alliance (BEA) for the Department of Energy (DOE). The final design report for the RH LLW Disposal Facility Project is a compilation of the documents and deliverables included in the facility final design.

Final Design Report for the RH LLW Disposal Facility (RDF) Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Austad, S. L.

2015-05-01

The RH LLW Disposal Facility (RDF) Project was designed by AREVA Federal Services (AFS) and the design process was managed by Battelle Energy Alliance (BEA) for the Department of Energy (DOE). The final design report for the RH LLW Disposal Facility Project is a compilation of the documents and deliverables included in the facility final design.

43 CFR 2804.19 - How will BLM process my Processing Category 6 application?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false How will BLM process my Processing... process my Processing Category 6 application? (a) For Processing Category 6 applications, you and BLM must enter into a written agreement that describes how BLM will process your application. The final agreement...

43 CFR 2804.19 - How will BLM process my Processing Category 6 application?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false How will BLM process my Processing... process my Processing Category 6 application? (a) For Processing Category 6 applications, you and BLM must enter into a written agreement that describes how BLM will process your application. The final agreement...

A novel model-based control strategy for aerobic filamentous fungal fed-batch fermentation processes.

PubMed

Mears, Lisa; Stocks, Stuart M; Albaek, Mads O; Cassells, Benny; Sin, Gürkan; Gernaey, Krist V

2017-07-01

A novel model-based control strategy has been developed for filamentous fungal fed-batch fermentation processes. The system of interest is a pilot scale (550 L) filamentous fungus process operating at Novozymes A/S. In such processes, it is desirable to maximize the total product achieved in a batch in a defined process time. In order to achieve this goal, it is important to maximize both the product concentration, and also the total final mass in the fed-batch system. To this end, we describe the development of a control strategy which aims to achieve maximum tank fill, while avoiding oxygen limited conditions. This requires a two stage approach: (i) calculation of the tank start fill; and (ii) on-line control in order to maximize fill subject to oxygen transfer limitations. First, a mechanistic model was applied off-line in order to determine the appropriate start fill for processes with four different sets of process operating conditions for the stirrer speed, headspace pressure, and aeration rate. The start fills were tested with eight pilot scale experiments using a reference process operation. An on-line control strategy was then developed, utilizing the mechanistic model which is recursively updated using on-line measurements. The model was applied in order to predict the current system states, including the biomass concentration, and to simulate the expected future trajectory of the system until a specified end time. In this way, the desired feed rate is updated along the progress of the batch taking into account the oxygen mass transfer conditions and the expected future trajectory of the mass. The final results show that the target fill was achieved to within 5% under the maximum fill when tested using eight pilot scale batches, and over filling was avoided. The results were reproducible, unlike the reference experiments which show over 10% variation in the final tank fill, and this also includes over filling. The variance of the final tank fill is reduced by over 74%, meaning that it is possible to target the final maximum fill reproducibly. The product concentration achieved at a given set of process conditions was unaffected by the control strategy. Biotechnol. Bioeng. 2017;114: 1459-1468. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

40 CFR 271.21 - Procedures for revision of State programs.

Code of Federal Regulations, 2013 CFR

2013-07-01

... immediate final decision takes effect or reverses the decision. (4) The procedures for proposed and final... Monitoring Activities, Methods Innovation Rule July 14, 2005 70 FR 34538, June 14, 2005 Process Vent and...

40 CFR 271.21 - Procedures for revision of State programs.

Code of Federal Regulations, 2014 CFR

2014-07-01

... immediate final decision takes effect or reverses the decision. (4) The procedures for proposed and final... Monitoring Activities, Methods Innovation Rule July 14, 2005 70 FR 34538, June 14, 2005 Process Vent and...

40 CFR 271.21 - Procedures for revision of State programs.

Code of Federal Regulations, 2011 CFR

2011-07-01

... immediate final decision takes effect or reverses the decision. (4) The procedures for proposed and final... Monitoring Activities, Methods Innovation Rule July 14, 2005 70 FR 34538, June 14, 2005 Process Vent and...

40 CFR 271.21 - Procedures for revision of State programs.

Code of Federal Regulations, 2012 CFR

2012-07-01

... immediate final decision takes effect or reverses the decision. (4) The procedures for proposed and final... Monitoring Activities, Methods Innovation Rule July 14, 2005 70 FR 34538, June 14, 2005 Process Vent and...

40 CFR 271.21 - Procedures for revision of State programs.

Code of Federal Regulations, 2010 CFR

2010-07-01

... immediate final decision takes effect or reverses the decision. (4) The procedures for proposed and final... Monitoring Activities, Methods Innovation Rule July 14, 2005 70 FR 34538, June 14, 2005 Process Vent and...

ScienceCasts: Cassini's Grand Finale

NASA Image and Video Library

2017-08-15

Cassini is in the process of executing 22 daring ‘Grand Finale’ dives in the 1,200-mile gap between Saturn and its innermost ring, concluding with an epic final plunge into the gas giant’s upper atmosphere.

Final Steps in Mating NuSTAR to its Rocket

NASA Image and Video Library

2012-02-23

Inside an environmental enclosure at Vandenberg Air Force Base processing facility in California, technicians complete the final steps in mating NASA Nuclear Spectroscopic Telescope Array NuSTAR and its Orbital Sciences Pegasus XL rocket.

Pre- and Post-Head Processing for Single- and Double-Scrambled Sentences of a Head-Final Language as Measured by the Eye Tracking Method

ERIC Educational Resources Information Center

Tamaoka, Katsuo; Asano, Michiko; Miyaoka, Yayoi; Yokosawa, Kazuhiko

2014-01-01

Using the eye-tracking method, the present study depicted pre- and post-head processing for simple scrambled sentences of head-final languages. Three versions of simple Japanese active sentences with ditransitive verbs were used: namely, (1) SO[subscript 1]O[subscript 2]V canonical, (2) SO[subscript 2]O[subscript 1]V single-scrambled, and (3)…

Bistatic SAR: Signal Processing and Image Formation.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wahl, Daniel E.; Yocky, David A.

This report describes the significant processing steps that were used to take the raw recorded digitized signals from the bistatic synthetic aperture RADAR (SAR) hardware built for the NCNS Bistatic SAR project to a final bistatic SAR image. In general, the process steps herein are applicable to bistatic SAR signals that include the direct-path signal and the reflected signal. The steps include preprocessing steps, data extraction to for a phase history, and finally, image format. Various plots and values will be shown at most steps to illustrate the processing for a bistatic COSMO SkyMed collection gathered on June 10, 2013more » on Kirtland Air Force Base, New Mexico.« less

Final report on the oxidation of energetic materials in supercritical water. Final Air Force report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Buelow, S.J.; Allen, D.; Anderson, G.K.

1995-04-03

The objective of this project was to determine the suitability of oxidation in supercritical fluids (SCO), particularly water (SCWO), for disposal of propellants, explosives, and pyrotechnics (PEPs). The SCO studies of PEPs addressed the following issues: The efficiency of destruction of the substrate. The products of destruction contained in the effluents. Whether the process can be conducted safely on a large scale. Whether energy recovery from the process is economically practicable. The information essential for process development and equipment design was also investigated, including issues such as practical throughput of explosives through a SCWO reactor, reactor materials and corrosion, andmore » models for process design and optimization.« less

ON THE SPIN CORRELATIONS OF MUONS AND TAU LEPTONS GENERATED IN THE ANNIHILATION PROCESSES e+e- → μ+μ-, e+e- → τ+τ-

NASA Astrophysics Data System (ADS)

Lyuboshitz, Valery V.; Lyuboshitz, Vladimir L.

2014-12-01

Using the technique of helicity amplitudes, the electromagnetic process e+e- → μ+μ-(τ+τ-) is theoretically studied in the one-photon approximation. The structure of the triplet states of the final (μ+μ-) system is analyzed. It is shown that in the case of unpolarized electron and positron the final muons are also unpolarized, but their spins are strongly correlated. Explicit expressions for the components of the correlation tensor of the (μ+μ-) system are derived. The formula for the angular correlation at the decays of final muons μ+ and μ- is obtained. It is demonstrated that spin correlations of muons in the considered process have the purely quantum character, since one of the Bell-type incoherence inequalities for the correlation tensor components is always violated.

Novel pre-alloyed powder processing of modified alnico 8: Correlation of microstructure and magnetic properties

DOE PAGES

Anderson, I. E.; Kassen, A. G.; White, E. M. H.; ...

2015-04-13

Progress is reviewed on development of an improved near-final bulk magnet fabrication process for alnico 8, as a non-rare earth permanent magnet with promise for sufficient energy density and coercivity for electric drive motors. This study showed that alnico bulk magnets in near-final shape can be made by simple compression molding from spherical high purity gas atomized pre-alloyed powder. Dwell time at peak sintering temperature (1250°C) greatly affected grain size of the resulting magnet alloys. This microstructure transformation was demonstrated to be useful for gaining partially aligned magnetic properties and boosting energy product. Furthermore, while a route to increased coercivitymore » was not identified by these experiments, manufacturability of bulk alnico magnet alloys in near-final shapes was demonstrated, permitting further processing and alloy modification experiments that can target higher coercivity and better control of grain anisotropy during grain growth.« less

Optimization of fed-batch enzymatic hydrolysis from alkali-pretreated sugarcane bagasse for high-concentration sugar production.

PubMed

Gao, Yueshu; Xu, Jingliang; Yuan, Zhenhong; Zhang, Yu; Liu, Yunyun; Liang, Cuiyi

2014-09-01

Fed-batch enzymatic hydrolysis process from alkali-pretreated sugarcane bagasse was investigated to increase solids loading, produce high-concentration fermentable sugar and finally to reduce the cost of the production process. The optimal initial solids loading, feeding time and quantities were examined. The hydrolysis system was initiated with 12% (w/v) solids loading in flasks, where 7% fresh solids were fed consecutively at 6h, 12h, 24h to get a final solids loading of 33%. All the requested cellulase loading (10 FPU/g substrate) was added completely at the beginning of hydrolysis reaction. After 120 h of hydrolysis, the maximal concentrations of cellobiose, glucose and xylose obtained were 9.376 g/L, 129.50 g/L, 56.03 g/L, respectively. The final total glucan conversion rate attained to 60% from this fed-batch process. Copyright © 2014. Published by Elsevier Ltd.

Graphoepitaxy integration and pattern transfer of lamellar silicon-containing high-chi block copolymers

NASA Astrophysics Data System (ADS)

Bézard, P.; Chevalier, X.; Legrain, A.; Navarro, C.; Nicolet, C.; Fleury, G.; Cayrefourcq, I.; Tiron, R.; Zelsmann, M.

2018-03-01

In this work, we present our recent achievements on the integration and transfer etching of a novel silicon-containing high-χ block copolymer for lines/spaces applications. Developed carbo-silane BCPs are synthesized under industrial conditions and present periodicities as low as 14 nm. A full directed self-assembly by graphoepitaxy process is shown using standard photolithography stacks and all processes are performed on 300 mm wafer compatible tools. Specific plasma processes are developed to isolate perpendicular lamellae and sub-12 nm features are finally transferred into silicon substrates. The quality of the final BCP hard mask (CDU, LWR, LER) are also investigated. Finally, thanks to the development of dedicated neutral layers and top-coats allowing perpendicular orientations, it was possible to investigate plasma etching experiments on full-sheets at 7 nm resolution, opening the way to the integration of these polymers in chemoepitaxy stacks.

Advantages of using a logarithmic scale in pressure-volume diagrams for Carnot and other heat engine cycles

NASA Astrophysics Data System (ADS)

Shieh, Lih-Yir; Kan, Hung-Chih

2014-04-01

We demonstrate that plotting the P-V diagram of an ideal gas Carnot cycle on a logarithmic scale results in a more intuitive approach for deriving the final form of the efficiency equation. The same approach also facilitates the derivation of the efficiency of other thermodynamic engines that employ adiabatic ideal gas processes, such as the Brayton cycle, the Otto cycle, and the Diesel engine. We finally demonstrate that logarithmic plots of isothermal and adiabatic processes help with visualization in approximating an arbitrary process in terms of an infinite number of Carnot cycles.

Single Event Effects mitigation with TMRG tool

NASA Astrophysics Data System (ADS)

Kulis, S.

2017-01-01

Single Event Effects (SEE) are a major concern for integrated circuits exposed to radiation. There have been several techniques proposed to protect circuits against radiation-induced upsets. Among the others, the Triple Modular Redundancy (TMR) technique is one of the most popular. The purpose of the Triple Modular Redundancy Generator (TMRG) tool is to automatize the process of triplicating digital circuits freeing the designer from introducing the TMR code manually at the implementation stage. It helps to ensure that triplicated logic is maintained through the design process. Finally, the tool streamlines the process of introducing SEE in gate level simulations for final verification.

Programming and machining of complex parts based on CATIA solid modeling

NASA Astrophysics Data System (ADS)

Zhu, Xiurong

2017-09-01

The complex parts of the use of CATIA solid modeling programming and simulation processing design, elaborated in the field of CNC machining, programming and the importance of processing technology. In parts of the design process, first make a deep analysis on the principle, and then the size of the design, the size of each chain, connected to each other. After the use of backstepping and a variety of methods to calculate the final size of the parts. In the selection of parts materials, careful study, repeated testing, the final choice of 6061 aluminum alloy. According to the actual situation of the processing site, it is necessary to make a comprehensive consideration of various factors in the machining process. The simulation process should be based on the actual processing, not only pay attention to shape. It can be used as reference for machining.

Burnishing of rotatory parts to improve surface quality

NASA Astrophysics Data System (ADS)

Celaya, A.; López de Lacalle, L. N.; Albizuri, J.; Alberdi, R.

2009-11-01

In this paper, the use of rolling burnishing process to improve the final quality of railway and automotive workpieces is studied. The results are focused on the improvement of the manufacturing processes of rotary workpieces used in railway and automotion industry, attending to generic target of achieving `maximum surface quality with minimal process time'. Burnishing is a finishing operation in which plastic deformation of surface irregularities occurs by applying pressure through a very hard element, a roller or a ceramic ball. This process gives additional advantages to the workpiece such as good surface roughness, increased hardness and high compressive residual stresses. The effect of the initial turning conditions on the final burnishing operation has also been studied. The results show that feeds used in the initial rough turning have little influence in the surface finish of the burnished workpieces. So, the process times of the combined turning and burnishing processes can be reduced, optimizing the shaft's machining process.

Plastic deformation history in infeed rotary swaging process

NASA Astrophysics Data System (ADS)

Liu, Yang; Herrmann, Marius; Schenck, Christian; Kuhfuss, Bernd

2017-10-01

In bulk forming processes, the net shape of a final product is achieved by plastic deformation as the material flows from the initial shape to the final shape of the workpiece. The material flow during the process is an important issue for its relationship with forging force, heat generation, microstructure transformation and energy consumption. Hence, the final properties of the product are directly influenced. Former researches showed that the material flow in the rotary swaging process is affected by different processing parameters like die angle, feeding velocity and friction condition. Thus, a profound knowledge of detailed material flow during the process is essential for a better understanding of the process. By using FEM, the material flow was investigated by the history of the plastic strain (PEEQ) development. In this study a 2D-axisymmetric model was built by using ABAQUS explicit. Both aluminum alloy (3.3206) and steel (1.0308) are studied with different feeding velocities and coefficients of friction. To achieve the development of PEEQ in different areas, the workpiece was divided into radial layers. The PEEQ history of each layer was tracked during the quasi-static forming process. Based on that, the plastic strain rate (PSR) was calculated and examined in a single stroke of the process. In that way, the material flow in different layers is presented and the material flow on the surface differs from that in the center, just the first 1/4 radial area from the surface is sensitive to different friction conditions.

Extension of effective date for temporary pilot program setting the time and place for a hearing before an administrative law judge. Final rule.

PubMed

2013-07-29

: We are extending our pilot program that authorizes the agency to set the time and place for a hearing before an administrative law judge (ALJ). This final rule will extend the pilot program for 1 year. The extension of the pilot program continues our commitment to improve the efficiency of our hearing process and maintain a hearing process that results in accurate, high-quality decisions for claimants. The current pilot program will expire on August 9, 2013. In this final rule, we are extending the effective date to August 9, 2014. We are making no other substantive changes.

Baselining current road weather information : final report

DOT National Transportation Integrated Search

2009-06-10

This final report contains research findings on the characterization of the quality and value of road weather information resources used by members of the surface transportation community in their decision-making process. The objectives of the projec...

2005 v4.3 Technical Support Document

EPA Pesticide Factsheets

Emissions Modeling for the Final Mercury and Air Toxics Standards Technical Support Document describes how updated 2005 NEI, version 2 emissions were processed for air quality modeling in support of the final Mercury and Air Toxics Standards (MATS).

Particle Engineering in Pharmaceutical Solids Processing: Surface Energy 
Considerations

PubMed Central

Williams, Daryl R.

2015-01-01

During the past 10 years particle engineering in the pharmaceutical industry has become a topic of increasing importance. Engineers and pharmacists need to understand and control a range of key unit manufacturing operations such as milling, granulation, crystallisation, powder mixing and dry powder inhaled drugs which can be very challenging. It has now become very clear that in many of these particle processing operations, the surface energy of the starting, intermediate or final products is a key factor in understanding the processing operation and or the final product performance. This review will consider the surface energy and surface energy heterogeneity of crystalline solids, methods for the measurement of surface energy, effects of milling on powder surface energy, adhesion and cohesion on powder mixtures, crystal habits and surface energy, surface energy and powder granulation processes, performance of DPI systems and finally crystallisation conditions and surface energy. This review will conclude that the importance of surface energy as a significant factor in understanding the performance of many particulate pharmaceutical products and processes has now been clearly established. It is still nevertheless, work in progress both in terms of development of methods and establishing the limits for when surface energy is the key variable of relevance. PMID:25876912

Knowledge transmission model with differing initial transmission and retransmission process

NASA Astrophysics Data System (ADS)

Wang, Haiying; Wang, Jun; Small, Michael

2018-10-01

Knowledge transmission is a cyclic dynamic diffusion process. The rate of acceptance of knowledge differs upon whether or not the recipient has previously held the knowledge. In this paper, the knowledge transmission process is divided into an initial and a retransmission procedure, each with its own transmission and self-learning parameters. Based on epidemic spreading model, we propose a naive-evangelical-agnostic (VEA) knowledge transmission model and derive mean-field equations to describe the dynamics of knowledge transmission in homogeneous networks. Theoretical analysis identifies a criterion for the persistence of knowledge, i.e., the reproduction number R0 depends on the minor effective parameters between the initial and retransmission process. Moreover, the final size of evangelical individuals is only related to retransmission process parameters. Numerical simulations validate the theoretical analysis. Furthermore, the simulations indicate that increasing the initial transmission parameters, including first transmission and self-learning rates of naive individuals, can accelerate the velocity of knowledge transmission efficiently but have no effect on the final size of evangelical individuals. In contrast, the retransmission parameters, including retransmission and self-learning rates of agnostic individuals, have a significant effect on the rate of knowledge transmission, i.e., the larger parameters the greater final density of evangelical individuals.

Treatment of landfill leachate by the Fenton process.

PubMed

Deng, Yang; Englehardt, James D

2006-12-01

In recent years, studies of leachate treatment by conventional Fenton, photo-Fenton and electro-Fenton processes have indicated that these methods can effectively reduce concentrations of organic contaminants and color. In addition, the process can increase the biodegradable fraction of organic constituents in leachate, particularly in mature or biologically recalcitrant leachate. Oxidation and coagulation both play important roles in the removal of organics. Initial pH, dosages of Fenton reagents, aeration, final pH, reagent addition mode, temperature, and UV irradiation may influence final treatment efficiency. In this paper, current knowledge of performance and economics of Fenton processes for treatment of landfill leachate as reported for laboratory, pilot and full-scale studies is reviewed, with the conclusion that the Fenton process is an important and competitive technology for the treatment or pretreatment of landfill leachate.

Application of a Model for Simulating the Vacuum Arc Remelting Process in Titanium Alloys

NASA Astrophysics Data System (ADS)

Patel, Ashish; Tripp, David W.; Fiore, Daniel

Mathematical modeling is routinely used in the process development and production of advanced aerospace alloys to gain greater insight into system dynamics and to predict the effect of process modifications or upsets on final properties. This article describes the application of a 2-D mathematical VAR model presented in previous LMPC meetings. The impact of process parameters on melt pool geometry, solidification behavior, fluid-flow and chemistry in Ti-6Al-4V ingots will be discussed. Model predictions were first validated against the measured characteristics of industrially produced ingots, and process inputs and model formulation were adjusted to match macro-etched pool shapes. The results are compared to published data in the literature. Finally, the model is used to examine ingot chemistry during successive VAR melts.

Design of Online Spheroidization Process for 1.0C-1.5Cr Bearing Steel and Microstructure Analysis

NASA Astrophysics Data System (ADS)

Li, Zhen-Xing; Li, Chang-Sheng; Ren, Jin-Yi; Li, Bin-Zhou; Suh, Dong-Woo

2018-02-01

Using thermo-mechanical control process, the online spheroidization annealing process of 1.0C-1.5Cr bearing steel was designed. Apart from intercritical online spheroidization (IS), a novel subcritical online spheroidization (SS) process was proposed, which is characterized by water-cooling to around 773 K (500 °C) after the final rolling pass, and then directly reheating to 973 K (700 °C) for isothermal holding. Compared with the results from the traditional offline spheroidization (TS) process, the size of spheroidized carbides is similar in both the TS and IS processes, whereas it is much smaller in the SS process. After spheroidization annealing, microstructure evolution during austenitization and quenching treatment was examined. It is shown that the refining of spheroidized carbides accelerates the dissolution of carbides during the austenitizing process, and decreases the size of undissolved carbides. In addition, the SS process can obtain finer prior austenite grain after quenching, which contributes to the enhancement of final hardness.

A retrospective review of how nonconformities are expressed and finalized in external inspections of health-care facilities.

PubMed

Hovlid, Einar; Høifødt, Helge; Smedbråten, Bente; Braut, Geir Sverre

2015-09-23

External inspections are widely used in health care as a means of improving the quality of care. However, the way external inspections affect the involved organization is poorly understood. A better understanding of these processes is important to improve our understanding of the varying effects of external inspections in different organizations. In turn, this can contribute to the development of more effective ways of conducting inspections. The way the inspecting organization states their grounds for noncompliant behavior and subsequently follows up to enforce the necessary changes can have implications for the inspected organization's change process. We explore how inspecting organizations express and state their grounds for noncompliant behavior and how they follow up to enforce improvements. We conducted a retrospective review, in which we performed a content analysis of the documents from 36 external inspections in Norway. Our analysis was guided by Donabedian's structure, process, and outcome model. Deficiencies in the management system in combination with clinical work processes was considered as nonconformity by the inspecting organizations. Two characteristic patterns were identified in the way observations led to a statement of nonconformity: one in which it was clearly demonstrated how deficiencies in the management system could affect clinical processes, and one in which this connection was not demonstrated. Two characteristic patterns were also identified in the way the inspecting organization followed up and finalized their inspection: one in which the inspection was finalized solely based on the documented changes in structural deficiencies addressed in the nonconformity statement, and one based on the documented changes in structural and process deficiencies addressed in the nonconformity statement. External inspections are performed to improve the quality of care. To accomplish this aim, we suggest that nonconformities should be grounded by observations that clearly demonstrate how deficiencies in the management system might affect the clinical processes, and that the inspection should be finalized based on documented changes in both structural and process deficiencies addressed in the nonconformity statement.

CMOS/SOS processing

NASA Technical Reports Server (NTRS)

Ramondetta, P.

1980-01-01

Report describes processes used in making complementary - metal - oxide - semiconductor/silicon-on-sapphire (CMOS/SOS) integrated circuits. Report lists processing steps ranging from initial preparation of sapphire wafers to final mapping of "good" and "bad" circuits on a wafer.

78 FR 18481 - Project-Level Predecisional Administrative Review Process

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-27

... Administrative Review Process AGENCY: Forest Service, USDA. ACTION: Final rule. SUMMARY: The United States... process by which the public may file objections seeking predecisional administrative review for proposed... for a predecisional objection process. Section 428 further directs the Secretary to apply these...

Automated Data Processing Support of Investigation and Security Missions at the Defense Investigative Service

DTIC Science & Technology

1990-03-29

This is our final report on the Audit of Automated Data Processing Support of Investigative and Security Missions at the Defense Investigative...Service for your information and use. Comments on a draft of this report were considered in preparing the final report. The audit was made from May through...October 1989. The objectives of the audit were to determine if the Defense Investigative Service (DIS) was effectively managing automated data

Processing and plating helical metallic coils

NASA Technical Reports Server (NTRS)

1972-01-01

The results of research efforts to develop an optimized nickel cobalt coating suitable as a recording medium are outlined. The coating is to be used directly on a BeCu helical coil substrate of a helical coil NASA recorder. Specifically, efforts were made to: optimize the coating thickness; establish processes and techniques adaptable for the production of finalized plated helical coils; design and fabricate the equipment required for production and testing of the coils; and deliver finalized helical coils to NASA.

COMBATXXI, JDAFS, and LBC Integration Requirements for EASE

DTIC Science & Technology

2015-10-06

process as linear and as new data is made available, any previous analysis is obsolete and has to start the process over again. Figure 2 proposes a...final line of the manifest file names the scenario file associated with the run. Under the usual practice, the analyst now starts the COMBATXXI...describes which events are to be logged. Finally the scenario is started with the click of a button. The simulation generates logs of a couple of sorts

BCQ+: a body constitution questionnaire to assess Yang-Xu. Part I: establishment of a first final version through a Delphi process.

PubMed

Su, Yi-Chang; Chen, Li-Li; Lin, Jun-Dai; Lin, Jui-Shan; Huang, Yi-Chia; Lai, Jim-Shoung

2008-12-01

Assessing an individual's level of Yang deficiency (Yang-Xu) by its manifestations is a frequent issue in traditional Chinese medicine (TCM) clinical trials. To this end, an objective, reliable and rigorous diagnostic tool is required. This study aimed to develop a first final version of the Yang-Xu Constitution Questionnaire. We conducted 3 steps to develop such an objective measurement tool: 1) the research team was formed and a panel of 26 experts was selected for the Delphi process; 2) items for the questionnaire were generated by literature review and a Delphi process; items were reworded into colloquial questions; face and content validity of the items were evaluated through a Delphi process again; 3) the difficulty of the questionnaire was evaluated in a pilot study with 81 subjects aged 20-60 years. The literature review retrieved 35 relevant items which matched the definition of 'constitution' and 'Yang-Xu'. After a first Delphi process, 22 items were retained and translated into colloquial questions. According to the second part of the Delphi process, the content validity index of each of the 22 questions ranged between 0.85-1. These 22 questions were evaluated by 81 subjects, 2 questions that were hard to tell the difference were combined; 3 questions were modified after the research team had discussed the participants' feedback. Finally, the questionnaire was established with 21 questions. This first final version of a questionnaire to assess Yang-Xu constitution with considerable face and content validity may serve as a basis to develop an advanced Yang-Xu questionnaire. 2008 S. Karger AG, Basel.

Optimization of conventional Fenton and ultraviolet-assisted oxidation processes for the treatment of reverse osmosis retentate from a paper mill.

PubMed

Hermosilla, Daphne; Merayo, Noemí; Ordóñez, Ruth; Blanco, Angeles

2012-06-01

According to current environmental legislation concerned with water scarcity, paper industry is being forced to adopt a zero liquid effluent policy. In consequence, reverse osmosis (RO) systems are being assessed as the final step of effluent treatment trains aiming to recover final wastewater and reuse it as process water. One of the most important drawbacks of these treatments is the production of a retentated stream, which is usually highly loaded with biorecalcitrant organic matter and inorganics; and this effluent must meet current legislation stringent constraints before being ultimately disposed. The treatment of biorefractory RO retentate from a paper mill by several promising advanced oxidation processes (AOPs) - conventional Fenton, photo-Fenton and photocatalysis - was optimized considering the effect and interaction of reaction parameters; particularly using response surface methodology (RSM) when appropriate (Fenton processes). The economical cost of these treatments was also comparatively assessed. Photo-Fenton process was able to totally remove the COD of the retentate, and resulted even operatively cheaper at high COD removal levels than conventional Fenton, which achieved an 80% reduction of the COD at best. In addition, although these optimal results were produced at pH=2.8, it was also tested that Fenton processes are able to achieve good COD reduction efficiencies (>60%) without adjusting the initial pH value, provided the natural pH of this wastewater was close to neutral. Finally, although TiO(2)-photocatalysis showed the least efficient and most expensive figures, it improved the biodegradability of the retentate, so its combination with a final biological step almost achieved the total removal of the COD. Copyright © 2011 Elsevier Ltd. All rights reserved.

Effects of asymmetric rolling process on ridging resistance of ultra-purified 17%Cr ferritic stainless steel

NASA Astrophysics Data System (ADS)

Lu, Cheng-zhuang; Li, Jing-yuan; Fang, Zhi

2018-02-01

In ferritic stainless steels, a significant non-uniform recrystallization orientation and a substantial texture gradient usually occur, which can degrade the ridging resistance of the final sheets. To improve the homogeneity of the recrystallization orientation and reduce the texture gradient in ultra-purified 17%Cr ferritic stainless steel, in this work, we performed conventional and asymmetric rolling processes and conducted macro and micro-texture analyses to investigate texture evolution under different cold-rolling conditions. In the conventional rolling specimens, we observed that the deformation was not uniform in the thickness direction, whereas there was homogeneous shear deformation in the asymmetric rolling specimens as well as the formation of uniform recrystallized grains and random orientation grains in the final annealing sheets. As such, the ridging resistance of the final sheets was significantly improved by employing the asymmetric rolling process. This result indicates with certainty that the texture gradient and orientation inhomogeneity can be attributed to non-uniform deformation, whereas the uniform orientation gradient in the thickness direction is explained by the increased number of shear bands obtained in the asymmetric rolling process.

Re-accumulation Scenarios Governing Final Global Shapes of Rubble-Pile Asteroids

NASA Astrophysics Data System (ADS)

Hestroffer, Daniel; Tanga, P.; Comito, C.; Paolicchi, P.; Walsh, K.; Richardson, D. C.; Cellino, A.

2009-05-01

Asteroids, since the formation of the solar system, are known to have experienced catastrophic collisions, which---depending on the impact energy---can produce a major disruption of the parent body and possibly give birth to asteroid families or binaries [1]. We present a general study of the final shape and dynamical state of asteroids produced by the re-accumulation process following a catastrophic disruption. Starting from a cloud of massive particles (mono-disperse spheres) with given density and velocity distributions, we analyse the final shape, spin state, and angular momentum of the system from numerical integration of a N-body gravitational system (code pkdgrav [2]). The re-accumulation process itself is relatively fast, with a dynamical time corresponding to the spin-period of the final body (several hours). The final global shapes---which are described as tri-axial ellipsoids---exhibit slopes consistent with a degree of shear stress sustained by interlocking particles. We point out a few results: -the final shapes are close to those of hydrostatic equilibrium for incompressible fluids, preferably Maclaurin spheroid rather than Jacobi ellipsoids -for bodies closest to the sequence of hydrostatic equilibrium, there is a direct relation between spin, density and outer shape, suggesting that the outer surface is nearly equipotential -the evolution of the shape during the process follows a track along a gradient of potential energy, without necessarily reaching its minimum -the loose random packing of the particles implies low friction angle and hence fluid-like behaviour, which extends the results of [3]. Future steps of our analysis will include feature refinements of the model initial conditions and re-accumulation process, including impact shakings, realistic velocity distributions, and non equal-sized elementary spheres. References [1] Michel P. et al. 2001. Science 294, 1696 [2] Leinhardt Z.M. et al. 2000. Icarus 146, 133 [3] Richardson D.C. et al. 2005. Icarus 173, 349

Process development of itaconic acid production by a natural wild type strain of Aspergillus terreus to reach industrially relevant final titers.

PubMed

Krull, Susan; Hevekerl, Antje; Kuenz, Anja; Prüße, Ulf

2017-05-01

Itaconic acid is a promising organic acid and is commercially produced by submerged fermentation of Aspergillus terreus. The cultivation process of the sensitive filamentous fungus has been studied intensively since 1932, with respect to fermentation media components, oxygen supply, shearing rate, pH value, or culture method. Whereas increased final titers were achieved over the years, the productivity has so far remained quite low. In this study, the impact of the pH on the itaconic acid production was investigated in detail. The pH during the growth and production phase had a significant influence on the final itaconic acid concentration and pellet diameter. The highest itaconic acid concentration of 160 g/L was achieved at a 1.5-L scale within 6.7 days by raising and controlling the pH value to pH 3.4 in the production phase. An ammonia solution and an increased phosphate concentration were used with an itaconic acid yield of 0.46 (w/w) and an overall productivity of 0.99 g/L/h in a fed-batch mode. A cultivation with a lower phosphate concentration resulted in an equal final concentration with an increased yield of 0.58 (w/w) after 11.8 days and an overall productivity of 0.57 g/L/h. This optimized process was successfully transferred from a 1.5-L scale to a 15-L scale. After 9.7 days, comparable pellet morphology and a final concentration of 150 g/L itaconic acid was reached. This paper provides a process strategy to yield a final titer of itaconic acid from a wild-type strain of A. terreus which is in the same range as the well-known citric acid production.

Prevalence and Persistence of Listeria monocytogenes in Ready-to-Eat Tilapia Sashimi Processing Plants.

PubMed

Chen, Bang-Yuan; Wang, Chung-Yi; Wang, Chia-Lan; Fan, Yang-Chi; Weng, I-Ting; Chou, Chung-Hsi

2016-11-01

A 2-year study was performed at two ready-to-eat tilapia sashimi processing plants (A and B) to identify possible routes of contamination with Listeria monocytogenes during processing. Samples were collected from the aquaculture environments, transportation tanks, processing plants, and final products. Seventy-nine L. monocytogenes isolates were found in the processing environments and final products; 3.96% (50 of 1,264 samples) and 3.86% (29 of 752 samples) of the samples from plants A and B, respectively, were positive for L. monocytogenes . No L. monocytogenes was detected in the aquaculture environments or transportation tanks. The predominant L. monocytogenes serotypes were 1/2b (55.70%) and 4b (37.97%); serotypes 3b and 4e were detected at much lower percentages. At both plants, most processing sections were contaminated with L. monocytogenes before the start of processing, which indicated that the cleaning and sanitizing methods did not achieve adequate pathogen removal. Eleven seropulsotypes were revealed by pulsed-field gel electrophoresis and serotyping. Analysis of seropulsotype distribution revealed that the contamination was disseminated by the processing work; the same seropulsotypes were repeatedly found along the work flow line and in the final products. Specific seropulsotypes were persistently found during different sampling periods, which suggests that the sanitation procedures or equipment used at these plants were inadequate. Plant staff should improve the sanitation procedures and equipment to reduce the risk of L. monocytogenes cross-contamination and ensure the safety of ready-to-eat tilapia products.

Termination in cognitive-behavioral therapy with children, adolescents, and parents.

PubMed

Vidair, Hilary B; Feyijinmi, Grace O; Feindler, Eva L

2017-03-01

The process of terminating cognitive-behavioral therapy (CBT) with families has been largely neglected in the literature, with the limited research focused on premature termination. This article describes the natural termination process in CBT with children, adolescents, and their parents. Based on existing theories, we describe a cognitive-behavioral model for: (a) initiating and engaging in discussion of termination, (b) processing the termination of treatment and the therapeutic relationship, (c) key aspects of the termination process in the final session, and (d) the very end of the final session (saying goodbye). For each of the 4 components, we review relevant theories, provide clinical exchanges to demonstrate techniques, and provide related research support. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Exploitation of a Self-limiting Process for Reproducible Formation of Ultrathin Ni(1-x)Pt(x) Silicide Films

DOE Office of Scientific and Technical Information (OSTI.GOV)

Z Zhang; B Yang; Y Zhu

This letter reports on a process scheme to obtain highly reproducible Ni{sub 1-x}Pt{sub x} silicide films of 3-6 nm thickness formed on a Si(100) substrate. Such ultrathin silicide films are readily attained by sputter deposition of metal films, metal stripping in wet chemicals, and final silicidation by rapid thermal processing. This process sequence warrants an invariant amount of metal intermixed with Si in the substrate surface region independent of the initial metal thickness, thereby leading to a self-limiting formation of ultrathin silicide films. The crystallographic structure, thickness, uniformity, and morphological stability of the final silicide films depend sensitively on themore » initial Pt fraction.« less

Nuclear Reactions and the ν p-Process

NASA Astrophysics Data System (ADS)

Fröhlich, Carla; Hatcher, Daniel; Perdikakis, Georgios; Nikas, Stylianos

In understanding the origin of the heavy elements, the "light heavy elements" pose a particular challenge: The two neutron-capture processes, r- and s-process, cannot explain the abundances patterns seen in very old galactic halo stars. A proposed solution to this problem is the ν p-process, which takes place in the strong neutrino-driven winds of core-collapse supernovae. In the ν p-process, a sequence of (n, p) and (p, γ ) reactions allows for the synthesis of elements with atomic numbers A > 64, which includes Sr, Y, Zr, and others possibly up to Sn. The relevant reaction rates are all based on statistical model predictions and carry some uncertainty. Here, the sensitivity of the final ν p-process abundance pattern on modifications of (n, p), (p, γ ), and (n, γ ) reactions are characterized. Only few reactions affect the final abundance pattern and hence warrant a more detailed study of the reaction rate.

Upholding professionalism: the disciplinary process of the American Academy of Neurology.

PubMed

Hutchins, John C; Sagsveen, Murray G; Larriviere, Dan

2010-12-14

To review the disciplinary process by which the American Academy of Neurology (AAN) enforces its formalized standards of professional conduct. We reviewed the AAN's Disciplinary Action Policy. We tracked the elapsed time from receipt to final decision of all allegations ("complaints") of improper conduct by AAN members submitted from 2004 to 2009. We placed each complaint into 1 of 4 categories: allegations of 1) improper expert witness testimony; 2) substandard care; 3) unprofessional conduct; 4) or both 2 and 3. We noted the type of complainant (AAN member or nonmember) and the final outcome for each complaint. The AAN's disciplinary process is a 5-step procedure with multiple reviewing bodies. From 2004 to 2009, the AAN received 3-16 complaints per year (total 58), with 16 filed each year in 2008 and 2009. Thirty-one complaints (53%) were submitted by nonmembers and 27 (47%) by members. Disciplinary action was recommended for 6 complaints (10.3%) with action taken in 3 (5.1%) and the member resigning in lieu of action in 3 (5.1%). The average number of days from receipt of complaint to final decision was 537, with an average of 890 days from 2004 to 2006, decreased to 184 days from 2007 to 2009. Recent revisions to the disciplinary process have increased efficiency and enhanced procedural safeguards. The AAN determined a mean of 12 months, from receipt of complaint to final decision rendered, is an appropriate benchmark when handling complaints. The AAN's disciplinary process upholds standards of professional conduct for AAN members and protects members from unsubstantiated complaints.

Analysis of microbiological contamination in mixed pressed ham and cooked sausage in Korea.

PubMed

Park, Myoung-Su; Wang, Jun; Park, Joong-Hyun; Forghani, Fereidoun; Moon, Jin-San; Oh, Deog-Hwan

2014-03-01

The objective of this study was to investigate the microbial contamination levels (aerobic bacteria plate count [APC], coliforms, Escherichia coli, Staphylococcus aureus, and Listeria monocytogenes) in mixed pressed ham and cooked sausage. A total of 180 samples were collected from factories with and without hazard analysis critical control point (HACCP) systems at four steps: after chopping (AC), after mixing (AM), cooling after the first heating process, and cooling after the second heating process. For ham, APCs and coliform and E. coli counts increased when ingredients were added to the meat at the AC step. Final product APC was 1.63 to 1.85 log CFU/g, and coliforms and E. coli were not detected. S. aureus and L. monocytogenes were found in nine (15.0%) and six (10.0%) samples, respectively, but only at the AC and AM steps and not in the final product. Sausage results were similar to those for ham. The final product APC was 1.52 to 3.85 log CFU/g, and coliforms and E. coli were not detected. S. aureus and L. monocytogenes were found in 29 (24.2%) and 25 (20.8%) samples at the AC and AM steps, respectively, but not in the final product. These results indicate that the temperature and time of the first and second heating are of extreme importance to ensure the microbiological safety of the final product regardless of whether a HACCP system is in place. Microorganism contamination must be monitored regularly and regulations regarding sanitization during processing should be improved. Education regarding employee personal hygiene, environmental hygiene, prevention of cross-contamination, ingredient control, and step-by-step process control is needed to reduce the risk of food poisoning.

A Course in Chemical Reactor Design.

ERIC Educational Resources Information Center

Takoudis, Christos G.

1983-01-01

Presents course outline, topics covered, and final project (doubling as a take home final exam) for a one-semester, interdisciplinary course on the design and behavior of chemical reactors. Interplay of chemical and physical rate processes is stressed in the course. (JM)

ATAC Process Proof of Concept Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bri Rolston; Sarah Freeman

Researchers at INL with funding from the Department of Energy’s Office of Electricity Delivery and Energy Reliability (DOE-OE) evaluated a novel approach for near real-time consumption of threat intelligence. Demonstration testing in an industry environment supported the development of this new process to assist the electric sector in securing their critical networks. This report provides the reader with an understanding of the methods used during this proof of concept project. The processes and templates were further advanced with an industry partner during an onsite assessment. This report concludes with lessons learned and a roadmap for final development of these materialsmore » for use by industry.« less

Power corrections in the N -jettiness subtraction scheme

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boughezal, Radja; Liu, Xiaohui; Petriello, Frank

We discuss the leading-logarithmic power corrections in the N-jettiness subtraction scheme for higher-order perturbative QCD calculations. We compute the next-to-leading order power corrections for an arbitrary N-jet process, and we explicitly calculate the power correction through next-to-next-to-leading order for color-singlet production for bothmore » $$q\\bar{q}$$ and gg initiated processes. Our results are compact and simple to implement numerically. Including the leading power correction in the N-jettiness subtraction scheme substantially improves its numerical efficiency. Finally, we discuss what features of our techniques extend to processes containing final-state jets.« less

Power corrections in the N -jettiness subtraction scheme

DOE PAGES

Boughezal, Radja; Liu, Xiaohui; Petriello, Frank

2017-03-30

We discuss the leading-logarithmic power corrections in the N-jettiness subtraction scheme for higher-order perturbative QCD calculations. We compute the next-to-leading order power corrections for an arbitrary N-jet process, and we explicitly calculate the power correction through next-to-next-to-leading order for color-singlet production for bothmore » $$q\\bar{q}$$ and gg initiated processes. Our results are compact and simple to implement numerically. Including the leading power correction in the N-jettiness subtraction scheme substantially improves its numerical efficiency. Finally, we discuss what features of our techniques extend to processes containing final-state jets.« less

Application of the quality by design approach to the drug substance manufacturing process of an Fc fusion protein: towards a global multi-step design space.

PubMed

Eon-duval, Alex; Valax, Pascal; Solacroup, Thomas; Broly, Hervé; Gleixner, Ralf; Strat, Claire L E; Sutter, James

2012-10-01

The article describes how Quality by Design principles can be applied to the drug substance manufacturing process of an Fc fusion protein. First, the quality attributes of the product were evaluated for their potential impact on safety and efficacy using risk management tools. Similarly, process parameters that have a potential impact on critical quality attributes (CQAs) were also identified through a risk assessment. Critical process parameters were then evaluated for their impact on CQAs, individually and in interaction with each other, using multivariate design of experiment techniques during the process characterisation phase. The global multi-step Design Space, defining operational limits for the entire drug substance manufacturing process so as to ensure that the drug substance quality targets are met, was devised using predictive statistical models developed during the characterisation study. The validity of the global multi-step Design Space was then confirmed by performing the entire process, from cell bank thawing to final drug substance, at its limits during the robustness study: the quality of the final drug substance produced under different conditions was verified against predefined targets. An adaptive strategy was devised whereby the Design Space can be adjusted to the quality of the input material to ensure reliable drug substance quality. Finally, all the data obtained during the process described above, together with data generated during additional validation studies as well as manufacturing data, were used to define the control strategy for the drug substance manufacturing process using a risk assessment methodology. Copyright © 2012 Wiley-Liss, Inc.

43 CFR 2884.17 - How will BLM process my Processing Category 6 application?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false How will BLM process my Processing...-WAY UNDER THE MINERAL LEASING ACT Applying for MLA Grants or TUPs § 2884.17 How will BLM process my... written agreement that describes how BLM will process your application. The final agreement consists of a...

43 CFR 2884.17 - How will BLM process my Processing Category 6 application?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false How will BLM process my Processing...-WAY UNDER THE MINERAL LEASING ACT Applying for MLA Grants or TUPs § 2884.17 How will BLM process my... written agreement that describes how BLM will process your application. The final agreement consists of a...

Mass Transit: Implementation of FTA’s New Starts Evaluation Process and FY 2001 Funding Proposals

DTIC Science & Technology

2000-04-01

formalize the process. FTA issued a proposed rule on April 7, 1999, and plans to issue final regulations by the summer of 2000. In selecting projects for...commit funds to any more New Starts projects during the last 2 years of TEA-21—through fiscal year 2003. Because there are plans for many more...regional review of alternatives, develop preliminary engineering plans , and meet FTA’s approval for the final design. TEA-21 requires that FTA evaluate

Membrane Bioreactor/Ultra Low Energy Reverse Osmosis Membrane Process for Forward Operating Base Wastewater Reuse

DTIC Science & Technology

2014-08-01

of the GEGR pilot membrane coater; b) configuration of the coating station; and c) web path of the dip-knife coating process for RO membrane...Energy-dispersive X-ray spectroscopy EPA Environmental Protection Agency F:M Food-To-Microorganism Ratio FOB Forward Operating Base FT- IR Fourier...report 03/2014 3.3 Submit draft Interim report/Go No-Go decision point white paper 05/2013 3.4 Submit final report 05/2014 3.5 Final debrief

Site selection for MSFC operational tests of solar heating and cooling systems

NASA Technical Reports Server (NTRS)

1978-01-01

The criteria, methodology, and sequence aspects of the site selection process are presented. This report organized the logical thought process that should be applied to the site selection process, but final decisions are highly selective.

Process development for automated solar cell and module production. Task 4: Automated array assembly

NASA Technical Reports Server (NTRS)

Hagerty, J. J.

1981-01-01

The Unimate robot was programmed for the final 35 cell pattern to be used in the fabrication of the deliverable modules. Mechanical construction of the Automated Lamination Station and Final Assembly Station were completed on schedule. All final wiring and interconnect cables were also completed and the first operational testing began. The final controlling program was written. A local fabricator was contracted to produce the glass reinforced concrete panels to be used for testing and deliverables. A video tape showing all three stations in operation was produced.

Onboard Monitoring and Reporting for Commercial Motor Vehicle Safety Final Report

DOT National Transportation Integrated Search

2008-02-01

This Final Report describes the process and product from the project, Onboard Monitoring and Reporting for Commercial Motor Vehicle Safety (OBMS), in which a prototypical suite of hardware and software on a class 8 truck was developed and tested. The...

Risk management. National Aeronautics and Space Administration (NASA). Interim rule adopted as final with changes.

PubMed

2000-11-22

This is a final rule amending the NASA FAR Supplement (NFS) to emphasize considerations of risk management, including safety, security (including information technology security), health, export control, and damage to the environment, within the acquisition process. This final rule addresses risk management within the context of acquisition planning, selecting sources, choosing contract type, structuring award fee incentives, administering contracts, and conducting contractor surveillance.

20 CFR 30.320 - Can a claim be reopened after the FAB has issued a final decision?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Can a claim be reopened after the FAB has... AMENDED Adjudicatory Process Reopening Claims § 30.320 Can a claim be reopened after the FAB has issued a final decision? (a) At any time after the FAB has issued a final decision pursuant to § 30.316, and...

Data breaches. Final rule.

PubMed

2008-04-11

This document adopts, without change, the interim final rule that was published in the Federal Register on June 22, 2007, addressing data breaches of sensitive personal information that is processed or maintained by the Department of Veterans Affairs (VA). This final rule implements certain provisions of the Veterans Benefits, Health Care, and Information Technology Act of 2006. The regulations prescribe the mechanisms for taking action in response to a data breach of sensitive personal information.

Evaluation of the effect of post-translational modification toward protein structure: Chemical synthesis of glycosyl crambins having either a high mannose-type or a complex-type oligosaccharide.

PubMed

Dedola, Simone; Izumi, Masayuki; Makimura, Yutaka; Ito, Yukishige; Kajihara, Yasuhiro

2016-11-04

Glycoproteins are assembled and folded in the endoplasmic reticulum (ER) and transported to the Golgi for further processing of their oligosaccharides. During these processes, two types of oligosaccharides are used: that is, high mannose-type oligosaccharide in the ER and complex-type oligosaccharide in the Golgi. We were interested to know how two different types of oligosaccharides could influence the folding pathway or the final three-dimensional structure of the glycoproteins. For this purpose, we synthesized a new glycosyl crambin having complex-type oligosaccharide and evaluated the folding process, the final protein structure analyzed by NMR, and compared the CD spectra with previously synthesized glycosyl crambin bearing high mannose-type oligosaccharides. From our analysis, we found that the two different oligosaccharides do not influence the folding pathway in vitro and the final structure of the small glycoproteins. © 2015 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 106: 446-452, 2016. © 2015 Wiley Periodicals, Inc.

PROPULSE 980: A Hydrogen Peroxide Enrichment System

NASA Technical Reports Server (NTRS)

Boxwell, Robert; Bromley, G.; Wanger, Robert; Pauls, Dan; Maynard, Bryon; McNeal, Curtis; Dumbacher, D. L. (Technical Monitor)

2000-01-01

The PROPULSE 980 unit is a transportable processing plant that enriches aerospace grade hydrogen peroxide from 90% to 98% final concentration. The unit was developed by Degussa-H Is, in cooperation with Orbital, NASA Marshall Space Center, and NASA Stennis Space Center. The system is a self-contained unit that houses all of the process equipment, instrumentation and controls to perform the concentration operation nearly autonomously. It is designed to produce non-bulk quantities of 98% hydrogen peroxide. The enrichment unit design also maintains system, personnel and environmental safety during all aspects of the enrichment process and final product storage. As part of the Propulse 980 checkout and final buyoff, it will be disassembled at the Degussa-H Is Corporation plant in Theodore, AL, transported to the Stennis Space Center, reassembled and subjected to a series of checkout tests to verify design objectives have been met. This paper will summarize the basic project elements and provide an update on the present status of the project.

Neutron diffraction measurement of residual stresses, dislocation density and texture in Zr-bonded U-10Mo “mini” fuel foils and plates

DOE PAGES

Brown, Donald William; Okuniewski, Maria A.; Sisneros, Thomas A.; ...

2016-12-01

Here, Al clad U-10Mo fuel plates are being considered for conversion of several research reactors from high-enriched to low-enriched U fuel. Neutron diffraction measurements of the textures, residual phase stresses, and dislocation densities in the individual phases of the mini-foils throughout several processing steps and following hot-isostatic pressing to the Al cladding, have been completed. Recovery and recrystallization of the bare U-10Mo fuel foil, as indicated by the dislocation density and texture, are observed depending on the state of the material prior to annealing and the duration and temperature of the annealing process. In general, the cladding procedure significantly reducesmore » the dislocation density, but the final state of the clad plate, both texture and dislocation density, depends strongly on the final processing step of the fuel foil. In contrast, the residual stress state of the final plate is dominated by the thermal expansion mismatch of the constituent materials.« less

Neutron diffraction measurement of residual stresses, dislocation density and texture in Zr-bonded U-10Mo “mini” fuel foils and plates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, Donald William; Okuniewski, Maria A.; Sisneros, Thomas A.

Here, Al clad U-10Mo fuel plates are being considered for conversion of several research reactors from high-enriched to low-enriched U fuel. Neutron diffraction measurements of the textures, residual phase stresses, and dislocation densities in the individual phases of the mini-foils throughout several processing steps and following hot-isostatic pressing to the Al cladding, have been completed. Recovery and recrystallization of the bare U-10Mo fuel foil, as indicated by the dislocation density and texture, are observed depending on the state of the material prior to annealing and the duration and temperature of the annealing process. In general, the cladding procedure significantly reducesmore » the dislocation density, but the final state of the clad plate, both texture and dislocation density, depends strongly on the final processing step of the fuel foil. In contrast, the residual stress state of the final plate is dominated by the thermal expansion mismatch of the constituent materials.« less

The effect of nozzle-exit-channel shape on resultant fiber diameter in melt-electrospinning

NASA Astrophysics Data System (ADS)

Esmaeilirad, Ahmad; Ko, Junghyuk; Rukosuyev, Maxym V.; Lee, Jason K.; Lee, Patrick C.; Jun, Martin B. G.

2017-01-01

In recent decades, electrospinning using a molten poly (ε-caprolactone) resin has gained attention for creating fibrous tissue scaffolds. The topography and diameter control of such electrospun microfibers is an important issue for their different applications in tissue engineering. Charge density, initial nozzle-exit-channel cross-sectional area, nozzle to collector distance, viscosity, and processing temperature are the most important input parameters that affect the final electrospun fiber diameters. In this paper we will show that the effect of nozzle-exit-channel shape is as important as the other effective parameters in a resultant fiber diameter. However, to the best of our knowledge, the effect of nozzle-exit-channel shapes on a resultant fiber diameter have not been studied before. Comparing rectangular and circular nozzles with almost the same exit-channel cross-sectional areas in a similar processing condition showed that using a rectangular nozzle resulted in decreasing final fiber diameter up to 50%. Furthermore, the effect of processing temperature on the final fiber topography was investigated.

Process-Structure Linkages Using a Data Science Approach: Application to Simulated Additive Manufacturing Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Popova, Evdokia; Rodgers, Theron M.; Gong, Xinyi

A novel data science workflow is developed and demonstrated to extract process-structure linkages (i.e., reduced-order model) for microstructure evolution problems when the final microstructure depends on (simulation or experimental) processing parameters. Our workflow consists of four main steps: data pre-processing, microstructure quantification, dimensionality reduction, and extraction/validation of process-structure linkages. These methods that can be employed within each step vary based on the type and amount of available data. In this paper, this data-driven workflow is applied to a set of synthetic additive manufacturing microstructures obtained using the Potts-kinetic Monte Carlo (kMC) approach. Additive manufacturing techniques inherently produce complex microstructures thatmore » can vary significantly with processing conditions. Using the developed workflow, a low-dimensional data-driven model was established to correlate process parameters with the predicted final microstructure. In addition, the modular workflows developed and presented in this work facilitate easy dissemination and curation by the broader community.« less

Process-Structure Linkages Using a Data Science Approach: Application to Simulated Additive Manufacturing Data

DOE PAGES

Popova, Evdokia; Rodgers, Theron M.; Gong, Xinyi; ...

2017-03-13

A novel data science workflow is developed and demonstrated to extract process-structure linkages (i.e., reduced-order model) for microstructure evolution problems when the final microstructure depends on (simulation or experimental) processing parameters. Our workflow consists of four main steps: data pre-processing, microstructure quantification, dimensionality reduction, and extraction/validation of process-structure linkages. These methods that can be employed within each step vary based on the type and amount of available data. In this paper, this data-driven workflow is applied to a set of synthetic additive manufacturing microstructures obtained using the Potts-kinetic Monte Carlo (kMC) approach. Additive manufacturing techniques inherently produce complex microstructures thatmore » can vary significantly with processing conditions. Using the developed workflow, a low-dimensional data-driven model was established to correlate process parameters with the predicted final microstructure. In addition, the modular workflows developed and presented in this work facilitate easy dissemination and curation by the broader community.« less

Reduction of Surface Errors over a Wide Range of Spatial Frequencies Using a Combination of Electrolytic In-Process Dressing Grinding and Magnetorheological Finishing

NASA Astrophysics Data System (ADS)

Kunimura, Shinsuke; Ohmori, Hitoshi

We present a rapid process for producing flat and smooth surfaces. In this technical note, a fabrication result of a carbon mirror is shown. Electrolytic in-process dressing (ELID) grinding with a metal bonded abrasive wheel, then a metal-resin bonded abrasive wheel, followed by a conductive rubber bonded abrasive wheel, and finally magnetorheological finishing (MRF) were performed as the first, second, third, and final steps, respectively in this process. Flatness over the whole surface was improved by performing the first and second steps. After the third step, peak to valley (PV) and root mean square (rms) values in an area of 0.72 x 0.54 mm2 on the surface were improved. These values were further improved after the final step, and a PV value of 10 nm and an rms value of 1 nm were obtained. Form errors and small surface irregularities such as surface waviness and micro roughness were efficiently reduced by performing ELID grinding using the above three kinds of abrasive wheels because of the high removal rate of ELID grinding, and residual small irregularities were reduced by short time MRF. This process makes it possible to produce flat and smooth surfaces in several hours.

Final assessment of nursing students in clinical practice: Perspectives of nursing teachers, students and mentors.

PubMed

Helminen, Kristiina; Johnson, Martin; Isoaho, Hannu; Turunen, Hannele; Tossavainen, Kerttu

2017-12-01

To describe the phenomenon of final assessment of the clinical practice of nursing students and to examine whether there were differences in assessments by the students and their teachers and mentors. Final assessment of students in clinical practice during their education has great importance for ensuring that enough high-quality nursing students are trained, as assessment tasks affect what the nursing student learns during the clinical practice. This study used descriptive, cross-sectional design. The population of this study comprised nursing students (n = 276) and their teachers (n = 108) in five universities of applied sciences in Finland as well as mentors (n = 225) who came from five partner hospitals. A questionnaire developed for this study contained questions about background variables as well as structured questions scored on a four-point scale, which also allowed the respondents to provide additional comments. When comparing the results related to nursing teachers' presence in the final assessment situation, it was found that teachers and mentors evaluated this as being carried out more often than nursing students suggested. Nursing students noted that fair and consistent assessment is carried out more often than nursing teachers thought. Mentors and teachers said that honest and direct criteria-based final assessment was carried out more often than nursing students evaluated. Nursing students and mentors need support from educational institutions and from nursing teachers in order to ensure the completion of a relevant assessment process. The findings of this study highlight an awareness of final assessment process. It is desirable to have a common understanding, for example, of how the assessment should be managed and what the assessment criteria are, as this will ensure a good quality process. © 2017 John Wiley & Sons Ltd.

The sentence wrap-up dogma.

PubMed

Stowe, Laurie A; Kaan, Edith; Sabourin, Laura; Taylor, Ryan C

2018-03-30

Current sentence processing research has focused on early effects of the on-line incremental processes that are performed at each word or constituent during processing. However, less attention has been devoted to what happens at the end of the clause or sentence. More specifically, over the last decade and a half, a lot of effort has been put into avoiding measuring event-related brain potentials (ERPs) at the final word of a sentence, because of the possible effects of sentence wrap-up. This article reviews the evidence on how and when sentence wrap-up impacts behavioral and ERP results. Even though the end of the sentence is associated with a positive-going ERP wave, thus far this effect has not been associated with any factors hypothesized to affect wrap-up. In addition, ERP responses to violations have not been affected by this positivity. "Sentence-final" negativities reported in the literature are not unique to sentence final positions, nor do they obscure or distort ERP effects associated with linguistic manipulations. Finally, the empirical evidence used to argue that sentence-final ERPs are different from those recorded at sentence-medial positions is weak at most. Measuring ERPs at sentence-final positions is therefore certainly not to be avoided at all costs, especially not in cases where the structure of the language under investigation requires it. More importantly, researchers should follow rigorous method in their experimental design, avoid decision tasks which may induce ERP confounds, and ensure all other possible explanations for results are considered. Although this article is directed at a particular dogma from a particular literature, this review shows that it is important to reassess what is regarded as "general knowledge" from time to time. Copyright © 2018 Elsevier B.V. All rights reserved.

10 CFR 765.21 - Procedures for processing reimbursement claims.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Department shall complete a final review of all relevant information prior to making a reimbursement decision... 10 Energy 4 2010-01-01 2010-01-01 false Procedures for processing reimbursement claims. 765.21... AND THORIUM PROCESSING SITES Procedures for Submitting and Processing Reimbursement Claims § 765.21...

Improvement in fermentation characteristics of degermed ground corn by lipid supplementation.

PubMed

Murthy, Ganti S; Singh, Vijay; Johnston, David B; Rausch, Kent D; Tumbleson, M E

2006-08-01

With rapid growth of fuel ethanol industry, and concomitant increase in distillers dried grains with solubles (DDGS), new corn fractionation technologies that reduce DDGS volume and produce higher value coproducts in dry grind ethanol process have been developed. One of the technologies, a dry degerm, defiber (3D) process (similar to conventional corn dry milling) was used to separate germ and pericarp fiber prior to the endosperm fraction fermentation. Recovery of germ and pericarp fiber in the 3D process results in removal of lipids from the fermentation medium. Biosynthesis of lipids, which is important for cell growth and viability, cannot proceed in strictly anaerobic fermentations. The effects of ten different lipid supplements on improving fermentation rates and ethanol yields were studied and compared to the conventional dry grind process. Endosperm fraction (from the 3D process) was mixed with water and liquefied by enzymatic hydrolysis and was fermented using simultaneous saccharification and fermentation. The highest ethanol concentration (13.7% v/v) was achieved with conventional dry grind process. Control treatment (endosperm fraction from 3D process without lipid supplementation) produced the lowest ethanol concentration (11.2% v/v). Three lipid treatments (fatty acid ester, alkylphenol, and ethoxylated sorbitan ester 1836) were most effective in improving final ethanol concentrations. Fatty acid ester treatment produced the highest final ethanol concentration (12.3% v/v) among all lipid supplementation treatments. Mean final ethanol concentrations of alkylphenol and ethoxylated sorbitan ester 1836 supplemented samples were 12.3 and 12.0% v/v, respectively.

Transit signal priority systems application and technology investigation : final report, March 2009.

DOT National Transportation Integrated Search

2009-03-01

This report describes the process and results of research to develop an evaluation process that will : assist NJ Transit in quickly determining which intersections are good candidates for Transit Signal : Priority (TSP). This evaluation process is ap...

Interpreting Chromosome Aberration Spectra

NASA Technical Reports Server (NTRS)

Levy, Dan; Reeder, Christopher; Loucas, Bradford; Hlatky, Lynn; Chen, Allen; Cornforth, Michael; Sachs, Rainer

2007-01-01

Ionizing radiation can damage cells by breaking both strands of DNA in multiple locations, essentially cutting chromosomes into pieces. The cell has enzymatic mechanisms to repair such breaks; however, these mechanisms are imperfect and, in an exchange process, may produce a large-scale rearrangement of the genome, called a chromosome aberration. Chromosome aberrations are important in killing cells, during carcinogenesis, in characterizing repair/misrepair pathways, in retrospective radiation biodosimetry, and in a number of other ways. DNA staining techniques such as mFISH ( multicolor fluorescent in situ hybridization) provide a means for analyzing aberration spectra by examining observed final patterns. Unfortunately, an mFISH observed final pattern often does not uniquely determine the underlying exchange process. Further, resolution limitations in the painting protocol sometimes lead to apparently incomplete final patterns. We here describe an algorithm for systematically finding exchange processes consistent with any observed final pattern. This algorithm uses aberration multigraphs, a mathematical formalism that links the various aspects of aberration formation. By applying a measure to the space of consistent multigraphs, we will show how to generate model-specific distributions of aberration processes from mFISH experimental data. The approach is implemented by software freely available over the internet. As a sample application, we apply these algorithms to an aberration data set, obtaining a distribution of exchange cycle sizes, which serves to measure aberration complexity. Estimating complexity, in turn, helps indicate how damaging the aberrations are and may facilitate identification of radiation type in retrospective biodosimetry.

Research to Assembly Scheme for Satellite Deck Based on Robot Flexibility Control Principle

NASA Astrophysics Data System (ADS)

Guo, Tao; Hu, Ruiqin; Xiao, Zhengyi; Zhao, Jingjing; Fang, Zhikai

2018-03-01

Deck assembly is critical quality control point in final satellite assembly process, and cable extrusion and structure collision problems in assembly process will affect development quality and progress of satellite directly. Aimed at problems existing in deck assembly process, assembly project scheme for satellite deck based on robot flexibility control principle is proposed in this paper. Scheme is introduced firstly; secondly, key technologies on end force perception and flexible docking control in the scheme are studied; then, implementation process of assembly scheme for satellite deck is described in detail; finally, actual application case of assembly scheme is given. Result shows that compared with traditional assembly scheme, assembly scheme for satellite deck based on robot flexibility control principle has obvious advantages in work efficiency, reliability and universality aspects etc.

Final Report of the NASA Technology Readiness Assessment (TRA) Study Team

NASA Technical Reports Server (NTRS)

Hirshorn, Steven; Jefferies, Sharon

2016-01-01

The material in this report covers the results on the NASA-wide TRA team, who are responsible for ascertaining the full extent of issues and ambiguities pertaining to TRATRL and to provide recommendations for mitigation. The team worked for approximately 6 months to become knowledgeable on the current TRATRL process and guidance and to derive recommendations for improvement.The team reviewed the TRA processes of other government agencies (OGA), including international agencies, and found that while the high-level processes are similar, the NASA process has a greater level of detail. Finally, NASA’s HQ OCT continues to monitor the GAO’s efforts to produce a TRA Best Practices Guide, a draft of which was received in February 2016. This Guide could impact the recommendations of this report.

77 FR 60039 - Non-Power Reactor License Renewal

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-02

... NUCLEAR REGULATORY COMMISSION 10 CFR Part 50 [NRC-2011-0087] RIN 3150-AI96 Non-Power Reactor... the final regulatory basis for rulemaking to streamline non-power reactor license renewal. This final... Reactor (RTR) License Renewal Process. This contemplated rulemaking also recommends conforming changes to...

Japanese Listeners' Perceptions of Phonotactic Violations

ERIC Educational Resources Information Center

Fais, Laurel; Kajikawa, Sachiyo; Werker, Janet; Amano, Shigeaki

2005-01-01

The canonical form for Japanese words is (Consonant)Vowel(Consonant) Vowel[approximately]. However, a regular process of high vowel devoicing between voiceless consonants and word-finally after voiceless consonants results in consonant clusters and word-final consonants, apparent violations of that phonotactic pattern. We investigated Japanese…

The Development of the Final Approach Spacing Tool (FAST): A Cooperative Controller-Engineer Design Approach

DOT National Transportation Integrated Search

1995-08-01

Historically, the development of advanced automation for air traffic control in : the United States has excluded the input of the air traffic controller until the : end of the development process. In contrast, the development of the Final : Approach ...

Baselining current road weather information : results of the 2010 quality and importance survey final report.

DOT National Transportation Integrated Search

2011-01-30

This final report contains research findings on the characterization of the quality and value of road weather information resources used by members of the surface transportation community in their decision-making process. This report focuses on the r...

76 FR 73475 - Immigration Benefits Business Transformation, Increment I; Correction

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-29

... to enable U.S. Citizenship and Immigration Services (USCIS) to transform its business processes. The... Transformation, Increment I; Correction AGENCY: U.S. Citizenship and Immigration Services, DHS. ACTION: Final....S. Citizenship and Immigration Services, Department of Homeland Security, 633 Third St. NW...

The Integration of Word Processing with Data Processing in an Educational Environment. Final Report.

ERIC Educational Resources Information Center

Patterson, Lorna; Schlender, Jim

A project examined the Office of the Future and determined trends regarding an integration of word processing and data processing. It then sought to translate those trends into an educational package to develop the potential information specialist. A survey instrument completed by 33 office managers and word processing and data processing…

Medicare program; revisions to the Medicare Advantage and Part D prescription drug contract determinations, appeals, and intermediate sanctions processes. Final rule with comment period.

PubMed

2007-12-05

This rule with comment period finalizes the Medicare program provisions relating to contract determinations involving Medicare Advantage (MA) organizations and Medicare Part D prescription drug plan sponsors, including eliminating the reconsideration process for review of contract determinations, revising the provisions related to appeals of contract determinations, and clarifying the process for MA organizations and Part D plan sponsors to complete corrective action plans. In this final rule with comment period, we also clarify the intermediate sanction and civil money penalty (CMP) provisions that apply to MA organizations and Medicare Part D prescription drug plan sponsors, modify elements of their compliance plans, retain voluntary self-reporting for Part D sponsors and implement a voluntary self-reporting recommendation for MA organizations, and revise provisions to ensure HHS has access to the books and records of MA organizations and Part D plan sponsors' first tier, downstream, and related entities. Although we have decided not to finalize the mandatory self-reporting provisions that we proposed, CMS remains committed to adopting a mandatory self-reporting requirement. To that end, we are requesting comments that will assist CMS in crafting a future proposed regulation for a mandatory self-reporting requirement.

Engineered Polymer Composites Through Electrospun Nanofiber Coating of Fiber Tows

NASA Technical Reports Server (NTRS)

Kohlman, Lee W.

2013-01-01

Toughening and other property enhancements of composite materials are typically implemented by-modifying the bulk properties of the constituents, either the fiber or matrix materials. This often leads to difficulties in processing and higher material costs. Many composites consist of tows or yarns (thousands of individual fibers) that are either filament wound or processed into a fabric by weaving or braiding. The matrix material can be added to the tow or fabric before final processing, resulting in a prepreg material, or infused into the fiber material during final processing by a variety of methods. By using a direct electrospun deposition method to apply thermoplastic nanofiber to the surface of the tows, the tow-tow interface in the resulting composite can be modified while using otherwise conventional materials and handling processes. Other materials of interest could also be incorporated into the electrospun precursor.

Case study: Lockheed-Georgia Company integrated design process

NASA Technical Reports Server (NTRS)

Waldrop, C. T.

1980-01-01

A case study of the development of an Integrated Design Process is presented. The approach taken in preparing for the development of an integrated design process includes some of the IPAD approaches such as developing a Design Process Model, cataloging Technical Program Elements (TPE's), and examining data characteristics and interfaces between contiguous TPE's. The implementation plan is based on an incremental development of capabilities over a period of time with each step directed toward, and consistent with, the final architecture of a total integrated system. Because of time schedules and different computer hardware, this system will not be the same as the final IPAD release; however, many IPAD concepts will no doubt prove applicable as the best approach. Full advantage will be taken of the IPAD development experience. A scenario that could be typical for many companies, even outside the aerospace industry, in developing an integrated design process for an IPAD-type environment is represented.

Scale Up of Malonic Acid Fermentation Process: Cooperative Research and Development Final Report, CRADA Number CRD-16-612

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schell, Daniel J

The goal of this work is to use the large fermentation vessels in the National Renewable Energy Laboratory's (NREL) Integrated Biorefinery Research Facility (IBRF) to scale-up Lygos' biological-based process for producing malonic acid and to generate performance data. Initially, work at the 1 L scale validated successful transfer of Lygos' fermentation protocols to NREL using a glucose substrate. Outside of the scope of the CRADA with NREL, Lygos tested their process on lignocellulosic sugars produced by NREL at Lawrence Berkeley National Laboratory's (LBNL) Advanced Biofuels Process Development Unit (ABPDU). NREL produced these cellulosic sugar solutions from corn stover using amore » separate cellulose/hemicellulose process configuration. Finally, NREL performed fermentations using glucose in large fermentors (1,500- and 9,000-L vessels) to intermediate product and to demonstrate successful performance of Lygos' technology at larger scales.« less

Stability of fumonisin B1, deoxynivalenol, zearalenone, and T-2 toxin during processing of traditional Nigerian beer and spices.

PubMed

Chilaka, Cynthia Adaku; De Boevre, Marthe; Atanda, Olusegun Oladimeji; De Saeger, Sarah

2018-05-03

The stability of the Fusarium mycotoxins fumonisin B 1 , deoxynivalenol, T-2 toxin, and zearalenone during processing of Nigerian traditional spices (dawadawa, okpehe, and ogiri) and beer (burukutu) using artificially contaminated raw materials was investigated. Results revealed the reduction of these toxins in all the final products. Boiling played a significant role (p < 0.05) in Fusarium mycotoxin reduction in the traditional spices. The highest percentage reduction of deoxynivalenol (76%) and zearalenone (74%) was observed during okpehe processing (boiled for 12 h). Dehulling and fermentation further demonstrated a positive influence on the reduction of these toxins with a total reduction ranging from 85 to 98% for dawadawa, 86 to 100% for okpehe, and 57 to 81% for ogiri. This trend was also observed during the production of traditional beer (burukutu), with malting and brewing playing a major impact in observed reduction. In addition, other metabolites including deoxynivalenol-3-glucoside, 15-acetyl-deoxynivalenol, α-zearalenol, and β-zearalenol which were initially not present in the raw sorghum were detected in the final beer product at the following concentrations 26 ± 11, 16 ± 7.7, 22 ± 18, and 31 ± 16 μg/kg, respectively. HT-2 toxin was also detected at a concentration of 36 ± 13 μg/kg along the processing chain (milled malted fraction) of the traditional beer. For the traditional spices, HT-2 toxin was detected (12 μg/kg) in ogiri. Although there was a reduction of mycotoxins during processing, appreciable concentrations of these toxins were still detected in the final products. Thus, the use of good quality raw materials significantly reduces mycotoxin contamination in final products.

Adapting Covariance Propagation to Account for the Presence of Modeled and Unmodeled Maneuvers

NASA Technical Reports Server (NTRS)

Schiff, Conrad

2006-01-01

This paper explores techniques that can be used to adapt the standard linearized propagation of an orbital covariance matrix to the case where there is a maneuver and an associated execution uncertainty. A Monte Carlo technique is used to construct a final orbital covariance matrix for a 'prop-burn-prop' process that takes into account initial state uncertainty and execution uncertainties in the maneuver magnitude. This final orbital covariance matrix is regarded as 'truth' and comparisons are made with three methods using modified linearized covariance propagation. The first method accounts for the maneuver by modeling its nominal effect within the state transition matrix but excludes the execution uncertainty by omitting a process noise matrix from the computation. The second method does not model the maneuver but includes a process noise matrix to account for the uncertainty in its magnitude. The third method, which is essentially a hybrid of the first two, includes the nominal portion of the maneuver via the state transition matrix and uses a process noise matrix to account for the magnitude uncertainty. The first method is unable to produce the final orbit covariance except in the case of zero maneuver uncertainty. The second method yields good accuracy for the final covariance matrix but fails to model the final orbital state accurately. Agreement between the simulated covariance data produced by this method and the Monte Carlo truth data fell within 0.5-2.5 percent over a range of maneuver sizes that span two orders of magnitude (0.1-20 m/s). The third method, which yields a combination of good accuracy in the computation of the final covariance matrix and correct accounting for the presence of the maneuver in the nominal orbit, is the best method for applications involving the computation of times of closest approach and the corresponding probability of collision, PC. However, applications for the two other methods exist and are briefly discussed. Although the process model ("prop-burn-prop") that was studied is very simple - point-mass gravitational effects due to the Earth combined with an impulsive delta-V in the velocity direction for the maneuver - generalizations to more complex scenarios, including high fidelity force models, finite duration maneuvers, and maneuver pointing errors, are straightforward and are discussed in the conclusion.

Analysis of procurement processes and development of recommendations for intelligent transportation systems (ITS) procurements : final report.

DOT National Transportation Integrated Search

2007-09-01

Traditional state procurement processes are not well-suited to the procurement of Intelligent Transportation Systems (ITS). The objective of this study was to analyze Kentuckys existing procurement processes, identify strengths and weaknesses of e...

Feasibility of a Modified Chloramine Process for the Production of UDMH and MMH

DTIC Science & Technology

1978-08-31

that phase is provided in this report . Amine Fuels Production Feasibility Demonstration, MCR -75-466, Final Report and Addendurn I - Data Book, Martin ...Final Report , Martin Marietta Corporation, Denver (February 1976) Contract F04701-74-C-0039. Amine Fuels Production Feasibility Demonstration, MCF-75...466, CDRL A305, Volume I, Final Report ; Volume II Economic Analyses; and Volume III, Data Book; Martin Marietta Corporation, Denver (October 1976

High-concentration sugars production from corn stover based on combined pretreatments and fed-batch process.

PubMed

Yang, Maohua; Li, Wangliang; Liu, Binbin; Li, Qiang; Xing, Jianmin

2010-07-01

In this paper, high-concentration sugars were produced from pretreated corn stover. The raw corn stover was pretreated in a process combining steam explosion and alkaline hydrogen-peroxide. The hemicellulose and lignin were removed greatly. The cellulose content increased to 73.2%. Fed-batch enzymatic hydrolysis was initiated with 12% (w/v) solids loading and 20 FPU/g solids. Then, 6% solids were fed consecutively at 12, 36 and 60 h. After 144 h, the final concentrations of reducing sugar, glucose, cellobiose and xylose reached 220, 175, 22 and 20 g/L, respectively. The final total biomass conversion was 60% in fed-batch process. Copyright 2009 Elsevier Ltd. All rights reserved.

Support services relating to geothermal programs. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1981-08-01

Activities designed to assist in the assessment of processes through which geopressured methane production and geopressure-geothermal power can be increased are discussed. Progress is reported on the following: general support, hot-dry-rock review, R and D plan, and the Edna Delcambre final report. (MHR)

An Experimental Approach to Debuccalization and Supplementary Gestures

ERIC Educational Resources Information Center

O'Brien, Jeremy

2012-01-01

Debuccalization is a weakening phenomenon whereby various consonants reduce to laryngeals. Examples include Spanish s-aspiration (s becomes h word-finally) and English t-glottalization (t becomes glottal stop syllable-finally). Previous analyses of debuccalization view it as a lenition process that deletes or manipulates formal phonological…

Model Orlando regionally efficient travel management coordination center (MORE TMCC), phase II : final report.

DOT National Transportation Integrated Search

2012-09-01

The final report for the Model Orlando Regionally Efficient Travel Management Coordination Center (MORE TMCC) presents the details of : the 2-year process of the partial deployment of the original MORE TMCC design created in Phase I of this project...

From Discrete to Continuous Process Simulation in Classical Thermodynamics: Irreversible Expansions of Ideal Monatomic Gases

ERIC Educational Resources Information Center

Álvarez-Rúa, Carmen; Borge, Javier

2016-01-01

Thermodynamic processes are complex phenomena that can be understood as a set of successive stages. When treating processes, classical thermodynamics (and most particularly, the Gibbsian formulation, predominantly used in chemistry) only pays attention to initial and final states. However, reintroducing the notion of process is absolutely…

Final state interactions at the threshold of Higgs boson pair production

NASA Astrophysics Data System (ADS)

Zhang, Zhentao

2015-11-01

We study the effect of final state interactions at the threshold of Higgs boson pair production in the Glashow-Weinberg-Salam model. We consider three major processes of the pair production in the model: lepton pair annihilation, ZZ fusion, and WW fusion. We find that the corrections caused by the effect for these processes are markedly different. According to our results, the effect can cause non-negligible corrections to the cross sections for lepton pair annihilation and small corrections for ZZ fusion, and this effect is negligible for WW fusion.

76 FR 37207 - Group Health Plans and Health Insurance Issuers: Rules Relating to Internal Claims and Appeals...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-24

...This document contains amendments to interim final regulations implementing the requirements regarding internal claims and appeals and external review processes for group health plans and health insurance coverage in the group and individual markets under provisions of the Affordable Care Act. These rules are intended to respond to feedback from a wide range of stakeholders on the interim final regulations and to assist plans and issuers in coming into full compliance with the law through an orderly and expeditious implementation process.

Integrated Process Modeling-A Process Validation Life Cycle Companion.

PubMed

Zahel, Thomas; Hauer, Stefan; Mueller, Eric M; Murphy, Patrick; Abad, Sandra; Vasilieva, Elena; Maurer, Daniel; Brocard, Cécile; Reinisch, Daniela; Sagmeister, Patrick; Herwig, Christoph

2017-10-17

During the regulatory requested process validation of pharmaceutical manufacturing processes, companies aim to identify, control, and continuously monitor process variation and its impact on critical quality attributes (CQAs) of the final product. It is difficult to directly connect the impact of single process parameters (PPs) to final product CQAs, especially in biopharmaceutical process development and production, where multiple unit operations are stacked together and interact with each other. Therefore, we want to present the application of Monte Carlo (MC) simulation using an integrated process model (IPM) that enables estimation of process capability even in early stages of process validation. Once the IPM is established, its capability in risk and criticality assessment is furthermore demonstrated. IPMs can be used to enable holistic production control strategies that take interactions of process parameters of multiple unit operations into account. Moreover, IPMs can be trained with development data, refined with qualification runs, and maintained with routine manufacturing data which underlines the lifecycle concept. These applications will be shown by means of a process characterization study recently conducted at a world-leading contract manufacturing organization (CMO). The new IPM methodology therefore allows anticipation of out of specification (OOS) events, identify critical process parameters, and take risk-based decisions on counteractions that increase process robustness and decrease the likelihood of OOS events.

FINAL REPORT FOR VERIFICATION OF THE METAL FINISHING FACILITY POLLUTION PREVENTION TOOL (MFFPPT)

EPA Science Inventory

The United States Environmental Protection Agency (USEPA) has prepared a computer process simulation package for the metal finishing industry that enables users to predict process outputs based upon process inputs and other operating conditions. This report documents the developm...

Patient protection and Affordable Care Act; data collection to support standards related to essential health benefits; recognition of entities for the accreditation of qualified health plans. Final rule.

PubMed

2012-07-20

This final rule establishes data collection standards necessary to implement aspects of section 1302 of the Patient Protection and Affordable Care Act (Affordable Care Act), which directs the Secretary of Health and Human Services to define essential health benefits. This final rule outlines the data on applicable plans to be collected from certain issuers to support the definition of essential health benefits. This final rule also establishes a process for the recognition of accrediting entities for purposes of certification of qualified health plans.

Process development for automated solar cell and module production. Task 4: Automated array assembly

NASA Technical Reports Server (NTRS)

Hagerty, J. J.

1981-01-01

Progress in the development of automated solar cell and module production is reported. The unimate robot is programmed for the final 35 cell pattern to be used in the fabrication of the deliverable modules. The mechanical construction of the automated lamination station and final assembly station phases are completed and the first operational testing is underway. The final controlling program is written and optimized. The glass reinforced concrete (GRC) panels to be used for testing and deliverables are in production. Test routines are grouped together and defined to produce the final control program.

Post Processing Methods used to Improve Surface Finish of Products which are Manufactured by Additive Manufacturing Technologies: A Review

NASA Astrophysics Data System (ADS)

Kumbhar, N. N.; Mulay, A. V.

2016-08-01

The Additive Manufacturing (AM) processes open the possibility to go directly from Computer-Aided Design (CAD) to a physical prototype. These prototypes are used as test models before it is finalized as well as sometimes as a final product. Additive Manufacturing has many advantages over the traditional process used to develop a product such as allowing early customer involvement in product development, complex shape generation and also save time as well as money. Additive manufacturing also possess some special challenges that are usually worth overcoming such as Poor Surface quality, Physical Properties and use of specific raw material for manufacturing. To improve the surface quality several attempts had been made by controlling various process parameters of Additive manufacturing and also applying different post processing techniques on components manufactured by Additive manufacturing. The main objective of this work is to document an extensive literature review in the general area of post processing techniques which are used in Additive manufacturing.

Plasmid fermentation process for DNA immunization applications.

PubMed

Carnes, Aaron E; Williams, James A

2014-01-01

Plasmid DNA for immunization applications must be of the highest purity and quality. The ability of downstream purification to efficiently produce a pure final product is directly influenced by the performance of the upstream fermentation process. While several clinical manufacturing facilities already have validated fermentation processes in place to manufacture plasmid DNA for use in humans, a simple and inexpensive laboratory-scale fermentation process can be valuable for in-house production of plasmid DNA for use in animal efficacy studies. This chapter describes a simple fed-batch fermentation process for producing bacterial cell paste enriched with high-quality plasmid DNA. A constant feeding strategy results in a medium cell density culture with continuously increasing plasmid amplification towards the end of the process. Cell banking and seed culture preparation protocols, which can dramatically influence final product yield and quality, are also described. These protocols are suitable for production of research-grade plasmid DNA at the 100 mg-to-1.5 g scale from a typical 10 L laboratory benchtop fermentor.

Influence of Homogenization and Thermal Processing on the Gastrointestinal Fate of Bovine Milk Fat: In Vitro Digestion Study.

PubMed

Liang, Li; Qi, Ce; Wang, Xingguo; Jin, Qingzhe; McClements, David Julian

2017-12-20

Dairy lipids are an important source of energy and nutrients for infants and adults. The dimensions, aggregation state, and interfacial properties of fat globules in raw milk are changed by dairy processing operations, such as homogenization and thermal processing. These changes influence the behavior of fat globules within the human gastrointestinal tract (GIT). The gastrointestinal fate of raw milk, homogenized milk, high temperature short time (HTST) pasteurized milk, and ultrahigh temperature (UHT) pasteurized milk samples was therefore determined using a simulated GIT. The properties of particles in different regions of the GIT depended on the degree of milk processing. Homogenization increased the initial lipid digestion rate but did not influence the final digestion extent. Thermal processing of homogenized milk decreased the initial rate and final extent of lipid digestion, which was attributed to changes in interfacial structure. These results provide insights into the impact of dairy processing on the gastrointestinal fate of milk fat.

24 CFR 58.56 - Scoping process.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Process: Procedures for Draft, Final and Supplemental Environmental Impact Statements § 58.56 Scoping... circumstances and factors as for the holding of public hearings under § 58.59. The responsible entity must wait...

24 CFR 58.56 - Scoping process.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Process: Procedures for Draft, Final and Supplemental Environmental Impact Statements § 58.56 Scoping... circumstances and factors as for the holding of public hearings under § 58.59. The responsible entity must wait...

24 CFR 58.56 - Scoping process.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Process: Procedures for Draft, Final and Supplemental Environmental Impact Statements § 58.56 Scoping... circumstances and factors as for the holding of public hearings under § 58.59. The responsible entity must wait...

24 CFR 58.56 - Scoping process.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Process: Procedures for Draft, Final and Supplemental Environmental Impact Statements § 58.56 Scoping... circumstances and factors as for the holding of public hearings under § 58.59. The responsible entity must wait...

24 CFR 58.56 - Scoping process.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Process: Procedures for Draft, Final and Supplemental Environmental Impact Statements § 58.56 Scoping... circumstances and factors as for the holding of public hearings under § 58.59. The responsible entity must wait...

Mesoscale fabrication and design

NASA Astrophysics Data System (ADS)

Hayes, Gregory R.

A strong link between mechanical engineering design and materials science and engineering fabrication can facilitate an effective and adaptable prototyping process. In this dissertation, new developments in the lost mold-rapid infiltration forming (LM-RIF) process is presented which demonstrates the relationship between these two fields of engineering in the context of two device applications. Within the LM-RIF process, changes in materials processing and mechanical design are updated iteratively, often aided by statistical design of experiments (DOE). The LM-RIF process was originally developed by Antolino and Hayes et al to fabricate mesoscale components. In this dissertation the focus is on advancements in the process and underlying science. The presented advancements to the LM-RIF process include an augmented lithography procedure, the incorporation of engineered aqueous and non-aqueous colloidal suspensions, an assessment of constrained drying forces during LM-RIF processing, mechanical property evaluation, and finally prototype testing and validation. Specifically, the molding procedure within the LM-RIF process is capable of producing molds with thickness upwards of 1mm, as well as multi-layering to create three dimensional structures. Increasing the mold thickness leads to an increase in the smallest feature resolvable; however, the increase in mold thickness and three dimensional capability has expanded the mechanical design space. Tetragonally stabilized zirconia (3Y-TZP) is an ideal material for mesoscale instruments, as it is biocompatible, exhibits high strength, and is chemically stable. In this work, aqueous colloidal suspensions were formulated with two new gel-binder systems, increasing final natural orifice translumenal endoscopic surgery (NOTES) instrument yield from 0% to upwards of 40% in the best case scenario. The effects of the gel-binder system on the rheological behavior of the suspension along with the thermal characteristics of the gel-binder system were characterized. Finally, mechanical properties of ceramic specimens were obtained via 3-point bend testing. Another candidate material for NOTES devices as well as cellular contact aided compliant mechanisms (C3M) devices is 300 series stainless steel (300 series stainless steel). 300 series stainless steel is a common biocompatible material; it is used in surgical applications, exhibits a high corrosion resistance, and has high strength to failure. New, high solids loading, non-aqueous colloidal suspensions of 300 series stainless steel were formulated and incorporated into the LM-RIF process. The rheological behavior and thermal characteristics of the non-aqueous colloidal suspensions were analyzed and engineered to operate within the LM-RIF process. Final part yield with the non-aqueous colloidal suspensions was higher than that of the aqueous ceramic suspensions. Mechanical properties of 300 series stainless steel specimens were determined via 3-point bend testing. Furthermore, new composite non-aqueous colloidal suspensions of 3Y-TZP and 300 series stainless steel were formulated and incorporated into the LM-RIF process. The composite materials showed an increase in final part yield, and an increase in yield strength compared to pure 300 series stainless steel was determined by Vickers hardness testing. The successful incorporation of composite suspensions in the LM-RIF process was facilitated through an analysis of the rheological behavior as a function of solids loading and ceramic to metal ratio. Optimized designs of NOTES instruments, as well as C3M devices were manufactured using the LM-RIF process with the non-aqueous 300 series stainless steel suspension. The performance of the prototype NOTES instruments was evaluated and compared against the theoretically predicted performance results, showing good agreement. Similarly, good agreement was seen between the stress-displacement behavior of prototype C3M devices when compared to the theoretically calculated stress-displacement results. Finally, in a comparison by endoscopic surgeons at Hershey Medical Center between an existing industry standard endoscopic device and the mesoscale instrument prototypes fabricated via the LM-RIF process, the prototype design performed favorably in almost all categories. (Abstract shortened by UMI.)

Cleanliness of Ti-bearing Al-killed ultra-low-carbon steel during different heating processes

NASA Astrophysics Data System (ADS)

Guo, Jian-long; Bao, Yan-ping; Wang, Min

2017-12-01

During the production of Ti-bearing Al-killed ultra-low-carbon (ULC) steel, two different heating processes were used when the converter tapping temperature or the molten steel temperature in the Ruhrstahl-Heraeus (RH) process was low: heating by Al addition during the RH decarburization process and final deoxidation at the end of the RH decarburization process (process-I), and increasing the oxygen content at the end of RH decarburization, heating and final deoxidation by one-time Al addition (process-II). Temperature increases of 10°C by different processes were studied; the results showed that the two heating processes could achieve the same heating effect. The T.[O] content in the slab and the refining process was better controlled by process-I than by process-II. Statistical analysis of inclusions showed that the numbers of inclusions in the slab obtained by process-I were substantially less than those in the slab obtained by process-II. For process-I, the Al2O3 inclusions produced by Al added to induce heating were substantially removed at the end of decarburization. The amounts of inclusions were substantially greater for process-II than for process-I at different refining stages because of the higher dissolved oxygen concentration in process-II. Industrial test results showed that process-I was more beneficial for improving the cleanliness of molten steel.

Inferring Causes of Biological Impairment in the Clear Fork Watershed, West Virginia (Final)

EPA Science Inventory

EPA announced the availability of the final report, Inferring Causes of Biological Impairment in the Clear Fork Watershed, West Virginia. This study illustrates a causal assessment in a watershed using the US EPA stressor identification process described on the www.epa....

Secondary aluminum industry final emissions test report: Culp Aluminum Alloys, Steele, Alabama. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The purpose of this testing program was to obtain emissions data for uncontrolled and controlled hydrochloric acid (HCl), particulate matter (PM) and speciated hydrocarbon Hazardous Air Pollutants (HAPs) from a secondary aluminum processing plant to support a national emission standard for hazardous air pollutants (NESHAP).

76 FR 12044 - Stainless Steel Bar From India: Preliminary Results of, and Partial Rescission of, the...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-04

... Facor did not experience significant differences in sales process/marketing support, freight/ delivery... Department re-examined Venus Wire's corporate affiliation relationship with Precision Metals for the instant administrative review. Because this relationship is unchanged from the 2005-2006 Final Results, 2007-2008 Final...

Sustainability of Promising Innovations, November 1, 1998-October 31, 2002. Final Report.

ERIC Educational Resources Information Center

Vadasy, Patricia

This final report discusses the activities and outcomes of a project designed to investigate the sustainability of two federally funded intervention programs by school staff. The first, Eastlake High School Inclusion Program, implemented processes and instructional interventions designed to support the full inclusion of students with disabilities…

78 FR 25388 - Significant New Use Rule on Ethoxylated, Propoxylated Diamine Diaryl Substituted Phenylmethane...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-01

...). ACTION: Final rule. SUMMARY: EPA is finalizing a significant new use rule (SNUR) under the Toxic Substances Control Act (TSCA) for the chemical substance identified generically as ethoxylated, propoxylated... manufacture, import, or process this chemical substance for an activity that is designated as a significant...

26 CFR 1.142(a)(6)-1 - Exempt facility bonds: solid waste disposal facilities.

Code of Federal Regulations, 2012 CFR

2012-04-01

... biological, engineering, industrial, or technological method. (1) Final disposal process. The term final... solid material derived from any agricultural, commercial, consumer, governmental, or industrial... industrial operation or activity, or a component of any such product or activity, and that has been used...

26 CFR 1.142(a)(6)-1 - Exempt facility bonds: solid waste disposal facilities.

Code of Federal Regulations, 2013 CFR

2013-04-01

... biological, engineering, industrial, or technological method. (1) Final disposal process. The term final... solid material derived from any agricultural, commercial, consumer, governmental, or industrial... industrial operation or activity, or a component of any such product or activity, and that has been used...

Interagency Planning and Support Project. Final Report.

ERIC Educational Resources Information Center

Salisbury, Christine

This final report describes the activities and outcomes of a federally funded project designed to develop, implement, and evaluate a systemically oriented process model for improving the coordination of education and human services for young children with identified disabilities and their families at the local level. The project developed and used…

Considerations for Developing a Dosimetry-Based Cumulative Risk Assessment Approach for Mixtures of Environmental Contaminants (Final Report)

EPA Science Inventory

EPA announced the availability of the final report, Considerations for Developing a Dosimetry-Based Cumulative Risk Assessment Approach for Mixtures of Environmental Contaminants. This report describes a process that can be used to determine the potential value of develop...

Naval Postgraduate School Scheduling Support System (NPS4)

DTIC Science & Technology

1992-03-01

NPSS ...... .................. 156 2. Final Exam Scheduler .. .......... 159 F. PRESENTATION SYSTEM ... ............. . 160 G. USER INTERFACE... NPSS ...... .................. 185 2. Final Exam Model ... ............ 186 3. The Class Schedulers .. .......... 186 4. Assessment of Problem Model...Information Distribution ....... 150 4.13 NPSS Optimization Process .... ............ . 157 4.14 NPSS Performance ..... ................ . 159 4.15 Department

10 CFR 710.29 - Final appeal process.

Code of Federal Regulations, 2010 CFR

2010-01-01

.... The Appeal Panel may also consider any other source of information that will advance the final... third member on the Appeal Panel; otherwise, the third member will be designated by the Chairman. Only... that it will not endanger the common defense and security and will be clearly consistent with the...

Stormwater Rules and Notices

EPA Pesticide Factsheets

Congress gives EPA authority to develop and implement federal stormwater regulations which must go through a rulemaking process. The process includes a proposal, public comment, and a final rule that must then be implemented and enforced.

Stormwater Discharges from Construction Activities

EPA Pesticide Factsheets

Congress gives EPA authority to develop and implement federal stormwater regulations which must go through a rulemaking process. The process includes a proposal, public comment, and a final rule that must then be implemented and enforced.

Hierarchical charge distribution controls self-assembly process of silk in vitro

NASA Astrophysics Data System (ADS)

Zhang, Yi; Zhang, Cencen; Liu, Lijie; Kaplan, David L.; Zhu, Hesun; Lu, Qiang

2015-12-01

Silk materials with different nanostructures have been developed without the understanding of the inherent transformation mechanism. Here we attempt to reveal the conversion road of the various nanostructures and determine the critical regulating factors. The regulating conversion processes influenced by a hierarchical charge distribution were investigated, showing different transformations between molecules, nanoparticles and nanofibers. Various repulsion and compressive forces existed among silk fibroin molecules and aggregates due to the exterior and interior distribution of charge, which further controlled their aggregating and deaggregating behaviors and finally formed nanofibers with different sizes. Synergistic action derived from molecular mobility and concentrations could also tune the assembly process and final nanostructures. It is suggested that the complicated silk fibroin assembly processes comply a same rule based on charge distribution, offering a promising way to develop silk-based materials with designed nanostructures.

Electrochemical Processes for In-Situ Treatment of Contaminated Soils - Final Report - 09/15/1996 - 01/31/2001

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, Chin-Pao

2001-05-31

This project will study electrochemical processes for the in situ treatment of soils contaminated by mixed wastes, i.e., organic and inorganic. Soil samples collected form selected DOE waste sites will be characterized for specific organic and metal contaminants and hydraulic permeability. The soil samples are then subject to desorption experiments under various physical-chemical conditions such as pH and the presence of surfactants. Batch electro-osmosis experiments will be conducted to study the transport of contaminants in the soil-water systems. Organic contaminants that are released from the soil substrate will be treated by an advanced oxidation process, i.e., electron-Fantan. Finally, laboratory reactormore » integrating the elector-osmosis and elector-Fantan processes will be used to study the treatment of contaminated soil in situ.« less

Reducing tensor magnetic gradiometer data for unexploded ordnance detection

USGS Publications Warehouse

Bracken, Robert E.; Brown, Philip J.

2005-01-01

We performed a survey to demonstrate the effectiveness of a prototype tensor magnetic gradiometer system (TMGS) for detection of buried unexploded ordnance (UXO). In order to achieve a useful result, we designed a data-reduction procedure that resulted in a realistic magnetic gradient tensor and devised a simple way of viewing complicated tensor data, not only to assess the validity of the final resulting tensor, but also to preview the data at interim stages of processing. The final processed map of the surveyed area clearly shows a sharp anomaly that peaks almost directly over the target UXO. This map agrees well with a modeled map derived from dipolar sources near the known target locations. From this agreement, it can be deduced that the reduction process is valid, making the prototype TMGS a foundation for development of future systems and processes.

Monitoring of an antigen manufacturing process.

PubMed

Zavatti, Vanessa; Budman, Hector; Legge, Raymond; Tamer, Melih

2016-06-01

Fluorescence spectroscopy in combination with multivariate statistical methods was employed as a tool for monitoring the manufacturing process of pertactin (PRN), one of the virulence factors of Bordetella pertussis utilized in whopping cough vaccines. Fluorophores such as amino acids and co-enzymes were detected throughout the process. The fluorescence data collected at different stages of the fermentation and purification process were treated employing principal component analysis (PCA). Through PCA, it was feasible to identify sources of variability in PRN production. Then, partial least square (PLS) was employed to correlate the fluorescence spectra obtained from pure PRN samples and the final protein content measured by a Kjeldahl test from these samples. In view that a statistically significant correlation was found between fluorescence and PRN levels, this approach could be further used as a method to predict the final protein content.

Influence of process parameters on content uniformity of a low dose active pharmaceutical ingredient in a tablet formulation according to GMP.

PubMed

Muselík, Jan; Franc, Aleš; Doležel, Petr; Goněc, Roman; Krondlová, Anna; Lukášová, Ivana

2014-09-01

The article describes the development and production of tablets using direct compression of powder mixtures. The aim was to describe the impact of filler particle size and the time of lubricant addition during mixing on content uniformity according to the Good Manufacturing Practice (GMP) process validation requirements. Processes are regulated by complex directives, forcing the producers to validate, using sophisticated methods, the content uniformity of intermediates as well as final products. Cutting down of production time and material, shortening of analyses, and fast and reliable statistic evaluation of results can reduce the final price without affecting product quality. The manufacturing process of directly compressed tablets containing the low dose active pharmaceutical ingredient (API) warfarin, with content uniformity passing validation criteria, is used as a model example. Statistic methods have proved that the manufacturing process is reproducible. Methods suitable for elucidation of various properties of the final blend, e.g., measurement of electrostatic charge by Faraday pail and evaluation of mutual influences of researched variables by partial least square (PLS) regression, were used. Using these methods, it was proved that the filler with higher particle size increased the content uniformity of both blends and the ensuing tablets. Addition of the lubricant, magnesium stearate, during the blending process improved the content uniformity of blends containing the filler with larger particles. This seems to be caused by reduced sampling error due to the suppression of electrostatic charge.

Longitudinal study on the sources of Listeria monocytogenes contamination in cold-smoked salmon and its processing environment in Italy.

PubMed

Di Ciccio, Pierluigi; Meloni, Domenico; Festino, Anna Rita; Conter, Mauro; Zanardi, Emanuela; Ghidini, Sergio; Vergara, Alberto; Mazzette, Rina; Ianieri, Adriana

2012-08-01

The aim of the present study was to investigate the sources of Listeria monocytogenes contamination in a cold smoked salmon processing environment over a period of six years (2003-2008). A total of 170 samples of raw material, semi-processed, final product and processing surfaces at different production stages were tested for the presence of L. monocytogenes. The L. monocytogenes isolates were characterized by multiplex PCR for the analysis of virulence factors and for serogrouping. The routes of contamination over the six year period were traced by PFGE. L. monocytogenes was isolated from 24% of the raw salmon samples, 14% of the semi-processed products and 12% of the final products. Among the environmental samples, 16% were positive for L. monocytogenes. Serotyping yielded three serovars: 1/2a, 1/2b, 4b, with the majority belonging to serovars 1/2a (46%) and 1/2b (39%). PFGE yielded 14 profiles: two of them were repeatedly isolated in 2005-2006 and in 2007-2008 mainly from the processing environment and final products but also from raw materials. The results of this longitudinal study highlighted that contamination of smoked salmon occurs mainly during processing rather than originating from raw materials, even if raw fish can be a contamination source of the working environment. Molecular subtyping is critical for the identification of the contamination routes of L. monocytogenes and its niches into the production plant when control strategies must be implemented with the aim to reduce its prevalence during manufacturing. Copyright © 2012 Elsevier B.V. All rights reserved.

Validation of contractor HMA testing data in the materials acceptance process - phase II : final report.

DOT National Transportation Integrated Search

2016-08-01

This study conducted an analysis of the SCDOT HMA specification. A Research Steering Committee provided oversight : of the process. The research process included extensive statistical analyses of test data supplied by SCDOT. : A total of 2,789 AC tes...

Thermo-mechanical simulation of liquid-supported stretch blow molding

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zimmer, J.; Stommel, M.

2015-05-22

Stretch blow molding is the well-established plastics forming method to produce Polyehtylene therephtalate (PET) bottles. An injection molded preform is heated up above the PET glass transition temperature (Tg∼85°C) and subsequently inflated by pressurized air into a closed cavity. In the follow-up filling process, the resulting bottle is filled with the final product. A recently developed modification of the process combines the blowing and filling stages by directly using the final liquid product to inflate the preform. In a previously published paper, a mechanical simulation and successful evaluation of this liquid-driven stretch blow molding process was presented. In this way,more » a realistic process parameter dependent simulation of the preform deformation throughout the forming process was enabled, whereas the preform temperature evolution during forming was neglected. However, the formability of the preform is highly reduced when the temperature sinks below Tg during forming. Experimental investigations show temperature-induced failure cases due to the fast heat transfer between hot preform and cold liquid. Therefore, in this paper, a process dependent simulation of the temperature evolution during processing to avoid preform failure is presented. For this purpose, the previously developed mechanical model is used to extract the time dependent thickness evolution. This information serves as input for the heat transfer simulation. The required material parameters are calibrated from preform cooling experiments recorded with an infrared-camera. Furthermore, the high deformation ratios during processing lead to strain induced crystallization. This exothermal reaction is included into the simulation by extracting data from preform measurements at different stages of deformation via Differential Scanning Calorimetry (DSC). Finally, the thermal simulation model is evaluated by free forming experiments, recorded by a high-speed infrared camera.« less

Design and optimization of a chromatographic purification process for Streptococcus pneumoniae serotype 23F capsular polysaccharide by a Design of Experiments approach.

PubMed

Ji, Yu; Tian, Yang; Ahnfelt, Mattias; Sui, Lili

2014-06-27

Multivalent pneumococcal vaccines were used worldwide to protect human beings from pneumococcal diseases. In order to eliminate the toxic organic solutions used in the traditional vaccine purification process, an alternative chromatographic process for Streptococcus pneumoniae serotype 23F capsular polysaccharide (CPS) was proposed in this study. The strategy of Design of Experiments (DoE) was introduced into the process development to solve the complicated design procedure. An initial process analysis was given to review the whole flowchart, identify the critical factors of chromatography through FMEA and chose the flowthrough mode due to the property of the feed. A resin screening study was then followed to select candidate resins. DoE was utilized to generate a resolution IV fractional factorial design to further compare candidates and narrow down the design space. After Capto Adhere was selected, the Box-Behnken DoE was executed to model the process and characterize all effects of factors on the responses. Finally, Monte Carlo simulation was used to optimize the process, test the chosen optimal conditions and define the control limit. The results of three scale-up runs at set points verified the DoE and simulation predictions. The final results were well in accordance with the EU pharmacopeia requirements: Protein/CPS (w/w) 1.08%; DNA/CPS (w/w) 0.61%; the phosphorus content 3.1%; the nitrogen 0.315% and the Methyl-pentose percentage 47.9%. Other tests of final pure CPS also met the pharmacopeia specifications. This alternative chromatographic purification process for pneumococcal vaccine without toxic organic solvents was successfully developed by the DoE approach and proved scalability, robustness and suitability for large scale manufacturing. Copyright © 2014 Elsevier B.V. All rights reserved.

Calendering and Rolling of Viscoplastic Materials: Theory and Experiments

NASA Astrophysics Data System (ADS)

Mitsoulis, E.; Sofou, S.; Muliawan, E. B.; Hatzikiriakos, S. G.

2007-04-01

The calendering and rolling processes are used in a wide variety of industries for the production of rolled sheets or films of specific thickness and final appearance. The acquired final sheet thickness depends mainly on the rheological properties of the material. Materials which have been used in the present study are foodstuff (such as mozzarella cheese and flour-water dough) used in food processing. These materials are rheologically viscoplastic, obeying the Herschel-Bulkley model. The results give the final sheet thickness and the torque as a function of the roll speed. Theoretical analysis based on the Lubrication Approximation Theory (LAT) shows that LAT is a good predictive tool for calendering, where the sheet thickness is very small compared with the roll size. However, in rolling where this is not true, LAT does not hold, and a 2-D analysis is necessary.

43 CFR 429.37 - Does interest accrue on monies owed to the United States during my appeal process?

Code of Federal Regulations, 2010 CFR

2010-10-01

... United States during my appeal process? 429.37 Section 429.37 Public Lands: Interior Regulations Relating... States during my appeal process? Except for any period in the appeal process during which a stay is then... decision to OHA, or during judicial review of final agency action. ...

Combination of an electrolytic pretreatment unit with secondary water reclamation processes

NASA Technical Reports Server (NTRS)

Wells, G. W.; Bonura, M. S.

1973-01-01

The design and fabrication of a flight concept prototype electrolytic pretreatment unit (EPU) and of a contractor-furnished air evaporation unit (AEU) are described. The integrated EPU and AEU potable water recovery system is referred to as the Electrovap and is capable of processing the urine and flush water of a six-man crew. Results of a five-day performance verification test of the Electrovap system are presented and plans are included for the extended testing of the Electrovap to produce data applicable to the combination of electrolytic pretreatment with most final potable water recovery systems. Plans are also presented for a program to define the design requirements for combining the electrolytic pretreatment unit with a reverse osmosis final processing unit.

49 CFR 7.32 - Final determinations.

Code of Federal Regulations, 2013 CFR

2013-10-01

... amount of work and/or time needed to process the appeal, or on the number of pages involved. (2) A...) Expedited processing. (1) An appeal will be taken out of order and given expedited treatment whenever a...

Watershed Simulation of Nutrient Processes

EPA Science Inventory

In this presentation, nitrogen processes simulated in watershed models were reviewed and compared. Furthermore, current researches on nitrogen losses from agricultural fields were also reviewed. Finally, applications with those models were reviewed and selected successful and u...

Stormwater Discharges from Construction Activities-2012 CGP

EPA Pesticide Factsheets

Congress gives EPA authority to develop and implement federal stormwater regulations which must go through a rulemaking process. The process includes a proposal, public comment, and a final rule that must then be implemented and enforced.

An update on methods for cryopreservation and thawing of hemopoietic stem cells.

PubMed

Lecchi, Lucilla; Giovanelli, Silvia; Gagliardi, Barbara; Pezzali, Ilaria; Ratti, Ilaria; Marconi, Maurizio

2016-06-01

The aim of this article is to review a number of variables that may affect the cryopreservation of minimally manipulated products containing allogeneic or autologous hemopoietic progenitor cells (HPC) used for transplantation, with particular reference to processing, type and addition of cryoprotectant, cell concentration, volume, freezing procedure, cooling rate, storage, thawing, and quality management. After defining final product's requirements in compliance with norms, laws and regulations, it is crucial to define the critical control points of the process. New approaches of processing were developed in the last few years such as automatic devices for volume reduction and high cell concentration in the frozen product. DMSO at 10% final concentration is still the most used cryoprotectant for HPC cryopreservation. Although controlled rate freezing is the recommended method for HPC cryopreservation, alternative methods may be used. Last generation vapor storage vessels ensure temperature stability better than older tanks. Their use may reduce risks of cross-contamination. Finally we review advantages and disadvantages of thawing procedures that may be carried out in the laboratory or at the patient's bedside. Copyright © 2016 Elsevier Ltd. All rights reserved.

Modifications of Saccharomyces pastorianus cell wall polysaccharides with brewing process.

PubMed

Bastos, Rita; Coelho, Elisabete; Coimbra, Manuel A

2015-06-25

The cell wall polysaccharides of brewers spent yeast Saccharomyces pastorianus (BSY) and the inoculum yeast (IY) were studied in order to understand the changes induced by the brewing process. The hot water and alkali extractions performed solubilized mainly mannoproteins, more branched for BSY than those of IY. Also, (31)P solid state NMR showed that the BSY mannoproteins were 3 times more phosphorylated. By electron microscopy it was observed that the final residues of alkali sequential extraction until 4M KOH preserved the yeast three-dimensional structure. The final residues, composed mainly by glucans (92%), showed that the BSY, when compared with IY, contained higher amount of (1→4)-linked Glc (43% for BSY and 16% for IY) and lower (1→3)-linked Glc (17% for BSY and 42% for IY). The enzymatic treatment of final residue showed that both BSY and IY had (α1→4)-linked Glc and (β1→4)-linked Glc, in a 2:1 ratio, showing that S. pastorianus increases their cellulose-like linkages with the brewing process. Copyright © 2015 Elsevier Ltd. All rights reserved.

Generation and performance assessment of the global TanDEM-X digital elevation model

NASA Astrophysics Data System (ADS)

Rizzoli, Paola; Martone, Michele; Gonzalez, Carolina; Wecklich, Christopher; Borla Tridon, Daniela; Bräutigam, Benjamin; Bachmann, Markus; Schulze, Daniel; Fritz, Thomas; Huber, Martin; Wessel, Birgit; Krieger, Gerhard; Zink, Manfred; Moreira, Alberto

2017-10-01

The primary objective of the TanDEM-X mission is the generation of a global, consistent, and high-resolution digital elevation model (DEM) with unprecedented global accuracy. The goal is achieved by exploiting the interferometric capabilities of the two twin SAR satellites TerraSAR-X and TanDEM-X, which fly in a close orbit formation, acting as an X-band single-pass interferometer. Between December 2010 and early 2015 all land surfaces have been acquired at least twice, difficult terrain up to seven or eight times. The acquisition strategy, data processing, and DEM calibration and mosaicking have been systematically monitored and optimized throughout the entire mission duration, in order to fulfill the specification. The processing of all data has finally been completed in September 2016 and this paper reports on the final performance of the TanDEM-X global DEM and presents the acquisition and processing strategy which allowed to obtain the final DEM quality. The results confirm the outstanding global accuracy of the delivered product, which can be now utilized for both scientific and commercial applications.

Nagy-Soper subtraction scheme for multiparton final states

NASA Astrophysics Data System (ADS)

Chung, Cheng-Han; Robens, Tania

2013-04-01

In this work, we present the extension of an alternative subtraction scheme for next-to-leading order QCD calculations to the case of an arbitrary number of massless final state partons. The scheme is based on the splitting kernels of an improved parton shower and comes with a reduced number of final state momentum mappings. While a previous publication including the setup of the scheme has been restricted to cases with maximally two massless partons in the final state, we here provide the final state real emission and integrated subtraction terms for processes with any number of massless partons. We apply our scheme to three jet production at lepton colliders at next-to-leading order and present results for the differential C parameter distribution.

Covert Response Patterns in Processing Language Stimuli. Final Report.

ERIC Educational Resources Information Center

McGuigan, F. Joseph

The purpose of this research project is to specify critical events within a person during linguistic processing. The experiments reported here cover such topics as the effects of increased reading rate on covert processes, covert behavior as a direct electro-myographic measure of mediating responses, enhancement of speech perception by…

Neuropsychological Components of Imagery Processing, Final Technical Report.

ERIC Educational Resources Information Center

Kosslyn, Stephen M.

High-level visual processes make use of stored information, and are invoked during object identification, navigation, tracking, and visual mental imagery. The work presented in this document has resulted in a theory of the component "processing subsystems" used in high-level vision. This theory was developed by considering…

Word/Information Processing with Microcomputers in Business Education. Final Narrative Report for the Exemplary Project.

ERIC Educational Resources Information Center

Ascension Parish School Board, Donaldsonville, LA.

This demonstration introduced microcomputers into St. Amant High School in Louisiana by instituting a word/information processing program. Microcomputers, printers, and necessary software were purchased, and the manufacturer's educational representative instructed the word/information processing teacher on the operation of the equipment. The…

44 CFR 9.8 - Public notice requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... for review and comment at the earliest possible time and throughout the decision-making process; and upon completion of this process, provide the public with an accounting of its final decisions (see § 9... for public involvement in the decision-making process through the provision of public notice upon...

How cheese is processed

USDA-ARS?s Scientific Manuscript database

This column continues the theme of "How Is It Processed?" with a focus on cheese. A fun fact is that it takes 10 pounds of milk to make one pound of cheese. Production of cheese is described in this column, as well as the effects of processing on the final properties of this popular food....

76 FR 55217 - Procedures for Protests and Contracts Dispute

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-07

... revised to clarify the standard for requesting a dismissal or summary decision, and the process for... revised to clarify when such a decision is to be construed as a final agency order. Adjudicative Process... practice and dismissal or summary decision of protests. 17.21 Adjudicative Process for protests. 17.23...

Developing a Methodology for Designing Systems of Instruction.

ERIC Educational Resources Information Center

Carpenter, Polly

This report presents a description of a process for instructional system design, identification of the steps in the design process, and determination of their sequence and interrelationships. As currently envisioned, several interrelated steps must be taken, five of which provide the inputs to the final design process. There are analysis of…

Final Technical Report - Advanced Optical Sensors to Minimize Energy Consumption in Polymer Extrusion Processes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Susan J. Foulk

Project Objective: The objectives of this study are to develop an accurate and stable on-line sensor system to monitor color and composition on-line in polymer melts, to develop a scheme for using the output to control extruders to eliminate the energy, material and operational costs of off-specification product, and to combine or eliminate some extrusion processes. Background: Polymer extrusion processes are difficult to control because the quality achieved in the final product is complexly affected by the properties of the extruder screw, speed of extrusion, temperature, polymer composition, strength and dispersion properties of additives, and feeder system properties. Extruder systemsmore » are engineered to be highly reproducible so that when the correct settings to produce a particular product are found, that product can be reliably produced time after time. However market conditions often require changes in the final product, different products or grades may be processed in the same equipment, and feed materials vary from lot to lot. All of these changes require empirical adjustment of extruder settings to produce a product meeting specifications. Optical sensor systems that can continuously monitor the composition and color of the extruded polymer could detect process upsets, drift, blending oscillations, and changes in dispersion of additives. Development of an effective control algorithm using the output of the monitor would enable rapid corrections for changes in materials and operating conditions, thereby eliminating most of the scrap and recycle of current processing. This information could be used to identify extruder systems issues, diagnose problem sources, and suggest corrective actions in real-time to help keep extruder system settings within the optimum control region. Using these advanced optical sensor systems would give extruder operators real-time feedback from their process. They could reduce the amount of off-spec product produced and significantly reduce energy consumption. Also, because blending and dispersion of additives and components in the final product could be continuously verified, we believe that, in many cases, intermediate compounding steps could be eliminated (saving even more time and energy).« less

Osmosis process for leachate treatment in industrial platform: Economic and performances evaluations to zero liquid discharge.

PubMed

Cingolani, Diego; Eusebi, Anna Laura; Battistoni, Paolo

2017-12-01

The industrial processes require large quantities of water. The presence of discharges results not only in significant environmental impact but implies wastage of water resources. This problem could be solved treating and reusing the produced wastewaters and applying the new zero liquid discharge approach. This paper discusses the design and the performances of reverse osmosis membranes for the upgrading of full scale platform for industrial liquid wastes. The final effluent from the ultrafiltration unit of the full scale plant was monitored to design the reverse osmosis unit. Previous modelling phase was used to evaluate the specific ordinary and maintenance costs and the final effluent quality (2.7 €/m 3 ). The system was designed in triple stages at different operative pressures. The economic feasibility and the payback period of the technology at different percentages of produced permeate were determined. The recovery of 90% was identified as profitable for the reverse osmosis application. One experimental pilot plant applying the reverse osmosis was used to test the final effluent. Moreover, the same flow was treated with second pilot system based on the forward osmosis process. The final efficiencies were compared. Removals higher than 95% using the reverse system were obtained for the main macropollutants and ions. No sustainable applicability of the forward osmosis was determined. Copyright © 2016 Elsevier Ltd. All rights reserved.

Microbial diversity and their roles in the vinegar fermentation process.

PubMed

Li, Sha; Li, Pan; Feng, Feng; Luo, Li-Xin

2015-06-01

Vinegar is one of the oldest acetic acid-diluted solution products in the world. It is produced from any fermentable sugary substrate by various fermentation methods. The final vinegar products possess unique functions, which are endowed with many kinds of compounds formed in the fermentation process. The quality of vinegar is determined by many factors, especially by the raw materials and microbial diversity involved in vinegar fermentation. Given that metabolic products from the fermenting strains are directly related to the quality of the final products of vinegar, the microbial diversity and features of the dominant strains involved in different fermentation stages should be analyzed to improve the strains and stabilize fermentation. Moreover, although numerous microbiological studies have been conducted to examine the process of vinegar fermentation, knowledge about microbial diversity and their roles involved in fermentation is still fragmentary and not systematic enough. Therefore, in this review, the dominant microorganism species involved in the stages of alcoholic fermentation and acetic acid fermentation of dissimilar vinegars were summarized. We also summarized various physicochemical properties and crucial compounds in disparate types of vinegar. Furthermore, the merits and drawbacks of vital fermentation methods were generalized. Finally, we described in detail the relationships among microbial diversity, raw materials, fermentation methods, physicochemical properties, compounds, functionality, and final quality of vinegar. The integration of this information can provide us a detailed map about the microbial diversity and function involved in vinegar fermentation.

Project Developmental Continuity Evaluation: Final Report. Volume II: The Process of Program Implementation in PDC.

ERIC Educational Resources Information Center

Wacker, Sally; And Others

The second of two volumes, this document continues the final evaluation report of Project Developmental Continuity (PDC), a Head Start demonstration project initiated in 1974 to develop program models which enhance children's social competence by fostering developmental continuity from preschool through the early elementary grades. In particular,…

9 CFR 112.2 - Final container label, carton label, and enclosure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... carton; (10) In the case of a product which contains an antibiotic added during the production process... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Final container label, carton label, and enclosure. 112.2 Section 112.2 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION...

49 CFR 1155.26 - Board determinations under 49 U.S.C. 10909.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 days prior to filing of application—Environmental report (and/or historic report, if applicable) filed and environmental process initiated pursuant to 49 CFR 1155.24. (i) Day 0—Application filed. (ii... date for initial comments. (iv) 30 days after the Final EIS (or other final environmental documentation...

State Compensatory Education. Final Technical Report 1975-76. Appendixes.

ERIC Educational Resources Information Center

Austin Independent School District, TX. Office of Research and Evaluation.

This material consists of ten appendixes to the Final Report for 1976-77 on the implementation of the Texas state-supported compensatory education program in the Austin Independent School District as evaluated by that district's Office of Research and Evaluation. The instruments used in the evaluation process are described or presented in full,…

What's in a Grade?

ERIC Educational Resources Information Center

Hughey, Jim D.; Harper, Bena

A study explored the processes and attitudes that occur when assigning students a final course grade. The final grades for 1,578 students in a basic communication course were used in discriminant analyses. The level (the mean of all grades given) and the spread (standard deviation of all grades given) were estimated for each of 17 instructors. The…

5 CFR 1639.28 - Coordinating salary offset with other agencies.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Coordinating salary offset with other... CLAIMS COLLECTION Salary Offset § 1639.28 Coordinating salary offset with other agencies. (a... employee is in the process of separating and has not received a final salary check or other final payment(s...

76 FR 47243 - Training and Employment Guidance (TEGL) Letter No. 15-06, Change 1, Special Procedures: Labor...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-04

... procedures, updated to reflect regulatory and organizational changes in the H-2A Program, for employers who... (the 2008 Final Rule). The 2008 Final Rule implemented an attestation-based application process and... reflect organizational changes, in addition to new regulatory and policy objectives. It replaces previous...

Composite lamination method

NASA Technical Reports Server (NTRS)

Dickerson, G. E. (Inventor)

1977-01-01

A process was developed for preparing relatively thick composite laminate structure wherein thin layers of prepreg tapes are assembled, these thin layers are cut into strips that are partially cured, and stacked into the desired thickness with uncured prepreg disposed between each layer of strips. The formed laminate is finally cured and thereafter machined to the desired final dimensions.

77 FR 23802 - Notice of Availability of a Final Environmental Impact Report/Environmental Impact Statement, a...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-20

... General Conformity Determination for the California High-Speed Train System Merced to Fresno Section... Environmental Impact Statement (EIS) and Final 4(f) Evaluation for the California High-Speed Train (HST) System...-Speed Rail Authority (Authority) is the lead state agency for the environmental review process. The...

Final inpatient rehabilitation PPS rule improves on proposed rule.

PubMed

Reynolds, M

2001-10-01

On August 7, 2001, the Centers for Medicare and Medicaid Services (CMS--formerly HCFA) released the final rule for a new prospective payment system (PPS) for inpatient rehabilitation services describing the process that must be used to receive payment for such services provided to Medicare beneficiaries. The process consists of five steps: First, a clinician performs assessments of the patient upon admission and at discharge. Second, the patient is classified into a case-mix group (CMG) with an assigned relative-value weight within that CMG. Third, the Federal prospective payment rate is determined by multiplying the relative-value weight by an annually updated, budget-neutral conversion factor. Fourth, the Federal prospective payment rate is adjusted to account for facility-specific factors. Finally, the facility-adjusted payment rate may be adjusted for case-specific factors. The final rule eliminates three deficiencies in the proposed rule by providing increased payment for treating any comorbidities documented prior to the second day before discharge, providing more appropriate payment for transfer cases, and minimizing the paperwork associated with patient assessment.

Neural Network Modeling for Gallium Arsenide IC Fabrication Process and Device Characteristics.

NASA Astrophysics Data System (ADS)

Creech, Gregory Lee, I.

This dissertation presents research focused on the utilization of neurocomputing technology to achieve enhanced yield and effective yield prediction in integrated circuit (IC) manufacturing. Artificial neural networks are employed to model complex relationships between material and device characteristics at critical stages of the semiconductor fabrication process. Whole wafer testing was performed on the starting substrate material and during wafer processing at four critical steps: Ohmic or Post-Contact, Post-Recess, Post-Gate and Final, i.e., at completion of fabrication. Measurements taken and subsequently used in modeling include, among others, doping concentrations, layer thicknesses, planar geometries, layer-to-layer alignments, resistivities, device voltages, and currents. The neural network architecture used in this research is the multilayer perceptron neural network (MLPNN). The MLPNN is trained in the supervised mode using the generalized delta learning rule. It has one hidden layer and uses continuous perceptrons. The research focuses on a number of different aspects. First is the development of inter-process stage models. Intermediate process stage models are created in a progressive fashion. Measurements of material and process/device characteristics taken at a specific processing stage and any previous stages are used as input to the model of the next processing stage characteristics. As the wafer moves through the fabrication process, measurements taken at all previous processing stages are used as input to each subsequent process stage model. Secondly, the development of neural network models for the estimation of IC parametric yield is demonstrated. Measurements of material and/or device characteristics taken at earlier fabrication stages are used to develop models of the final DC parameters. These characteristics are computed with the developed models and compared to acceptance windows to estimate the parametric yield. A sensitivity analysis is performed on the models developed during this yield estimation effort. This is accomplished by analyzing the total disturbance of network outputs due to perturbed inputs. When an input characteristic bears no, or little, statistical or deterministic relationship to the output characteristics, it can be removed as an input. Finally, neural network models are developed in the inverse direction. Characteristics measured after the final processing step are used as the input to model critical in-process characteristics. The modeled characteristics are used for whole wafer mapping and its statistical characterization. It is shown that this characterization can be accomplished with minimal in-process testing. The concepts and methodologies used in the development of the neural network models are presented. The modeling results are provided and compared to the actual measured values of each characteristic. An in-depth discussion of these results and ideas for future research are presented.

Processing Solvent Dependent Morphology of Diketopyrrolopyrrole (DPP) based Low Band Gap Polymer and PCBM Blends

NASA Astrophysics Data System (ADS)

Ferdous, Sunzida; Liu, Feng; Russell, Thomas

2013-03-01

Solution processing of polymer semiconductors is widely used for fabrication of low cost organic solar cells. Recently, mixed solvent systems or additive based systems for fabricating polymer solar cells have proven to be beneficial for obtaining high performance devices with multi-length scale morphologies. To control the morphology during the processing step, one needs to understand the effect of solvent as it evaporates to form the final thin film structure. In this study, we used diketopyrrolopyrrole (DPP) based low band gap polymer and phenyl-C71-butyric acid methyl ester (PCBM) blend in a series of mixed solvent systems consisting of a good solvent for both of the active material components, as well as different solvents that are good solvents for PCBM, but poor solvents for the polymer. Different evaporation times of the poor solvents during the drying process, and different solubility of the polymer in these poor solvents as well as their interaction with the substrate play an important role in the final morphology. In-situ GIWAXS studies were performed to observe the evolution of the structure as the solvent evaporates. The final morphologies of the thin film devices were also characterized by AFM, TEM, and various x-ray scattering techniques to correlate the morphology with the obtained device performances.

Patient Protection and Affordable Care Act; standards related to essential health benefits, actuarial value and accreditation. Final rule.

PubMed

2013-02-25

This final rule sets forth standards for health insurance issuers consistent with title I of the Patient Protection and Affordable Care Act, as amended by the Health Care and Education Reconciliation Act of 2010, referred to collectively as the Affordable Care Act. Specifically, this final rule outlines Exchange and issuer standards related to coverage of essential health benefits and actuarial value. This rule also finalizes a timeline for qualified health plans to be accredited in Federally-facilitated Exchanges and amends regulations providing an application process for the recognition of additional accrediting entities for purposes of certification of qualified health plans.

75 FR 18725 - Organization; Eligibility and Scope of Financing; Funding and Fiscal Affairs, Loan Policies and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-12

...The Farm Credit Administration (FCA or we) issues this final rule on Farm Credit System (System) bank and association director elections and other voting procedures. The final rule clarifies director election processes and updates FCA regulations to incorporate interpretations made through bookletters to System institutions. It also consolidates general election procedures, clarifies the role of nominating committees, enhances eligibility and disclosure requirements for director candidates, and improves annual meeting information statement instructions. The final rule also adds new regulations on floor nominations and meetings of stockholders. We expect this final rule will increase stockholder participation, enhance impartiality, and strengthen disclosures in director elections.

Dust formation at low metallicity

NASA Astrophysics Data System (ADS)

Ferrarotti, A. S.; Gail, H.-P.

Stars between 3Modot and 25Modot reach their final stages of stellar evolution either as AGB (asymptotic giant branch) stars and finally become white dwarfs, or end in a supernova explosion. The last evolutionary stages, shortly before the final state, are regularly accompanied by stellar winds which lead to substantial mass loss and develop optically very thick dust shells. Mass loss for smaller and medium sized stars higher up on the AGB depends predominantly on the metallicity of the star. For Pop I metallicity, the mass loss is caused by dust condensation. This process is not possible for stars of small Z. Thus, their final evolution strongly depends on the possibility of dust formation. Our research focuses on the dependence of dust formation of the first stellar generation on Z and on the initial mass of the star. Furthermore, we investigate when dust formation becomes possible in stellar winds and the effects this process has on the evolution of the star at the final evolutionary stages. With synthetic AGB evolution models some important issues in stellar evolution can tried to be answered: (1) mass loss on the AGB, (2) the shift of the limit (γ>1) for the onset of dust driven winds with Z and (3) the critical Z when dust formation becomes possible.

Federal Employees Health Benefits Program: Removal of Eligible and Ineligible Individuals From Existing Enrollments. Final rule.

PubMed

2018-01-23

The United States Office of Personnel Management (OPM) is issuing a final rule amending Federal Employees Health Benefits (FEHB) Program regulations to provide a process for removal of certain identified individuals who are found not to be eligible as family members from FEHB enrollments. This process would apply to individuals for whom there is a failure to provide adequate documentation of eligibility when requested. This action also amends Federal Employees Health Benefits (FEHB) Program regulations to allow certain eligible family members to be removed from existing self and family or self plus one enrollments.

Final Rule to Reduce Toxic Air Emissions from Asphalt Processing and Asphalt Roofing Manufacturing Facilities Fact Sheet

EPA Pesticide Factsheets

This page contains a February 2003 fact sheet with information regarding the National Emissions Standards for Hazardous Air Pollutants (NESHAP) for Asphalt Processing and Asphalt Roofing Manufacturing.

EPIC : expedited processing at international crossings : evaluation final report

DOT National Transportation Integrated Search

1998-09-01

This executive summary presents an overview of the Expedited Processing at International Crossings (EPIC) Field Operational Test (FOT). The EPIC focus was on the commercial vehicle transport component of international border crossings at the Nogales,...

Fact Sheet - Final Air Toxics Rule for Gold Mine Ore Processing and Production

EPA Pesticide Factsheets

Fact sheet summarizing main points of National Emissions Standards for Hazardous Air Pollutants for gold ore processing and production facilities, the seventh largest source of mercury air emission in the United States.

Implementation of advanced LCNG fueling infrastructure in Texas along the I-35/NAFTA Clean Corridor Project. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Taylor, Stan; Hightower, Jared; Knight, Koby

This report documents the process of planning, siting, and permitting recent LCNG station projects; identifying existing constraints in these processes, and recommendations for improvements; LCNG operating history.

Improving the effectiveness of partnering : final report.

DOT National Transportation Integrated Search

2002-11-01

The objectives of the research were to: (1) assess the current state of the Oregon Department of Transportations (ODOT) partnering program; (2) examine ways for improving current processes; and (3) recommend process improvements and possible new m...

Automatic small target detection in synthetic infrared images

NASA Astrophysics Data System (ADS)

Yardımcı, Ozan; Ulusoy, Ä.°lkay

2017-05-01

Automatic detection of targets from far distances is a very challenging problem. Background clutter and small target size are the main difficulties which should be solved while reaching a high detection performance as well as a low computational load. The pre-processing, detection and post-processing approaches are very effective on the final results. In this study, first of all, various methods in the literature were evaluated separately for each of these stages using the simulated test scenarios. Then, a full system of detection was constructed among available solutions which resulted in the best performance in terms of detection. However, although a precision rate as 100% was reached, the recall values stayed low around 25-45%. Finally, a post-processing method was proposed which increased the recall value while keeping the precision at 100%. The proposed post-processing method, which is based on local operations, increased the recall value to 65-95% in all test scenarios.

Roles of epigenome in mammalian spermatogenesis.

PubMed

Song, Ning; Endo, Daisuke; Koji, Takehiko

2014-04-01

Mammalian spermatogenesis is a successive process consisting of spermatogonial proliferation, spermatocytic meiosis, and spermiogenesis, representing the maturation of haploid spermatids. During the process, 25-75 % of the expected sperm yield is thought to be lost through apoptosis. In addition, spermatogenesis is considered to be a process undergoing successive heterochromatinization, finally reaching a complete condensed form in the sperm head. Thus, cell proliferation, differentiation and death may be strictly regulated by epigenetic factors in this process. This review describes the current understanding of the role of epigenome in spermatogenesis, especially focusing on the following aspects; DNA methylation, modification of histones, and small RNA function. These epigenetic factors affect each other and play a central role in events essential for spermatogenesis, fertilization and embryogenesis, through the regulation of gene expression, transposon activities, meiotic sex chromosome inactivation, histone remodeling and genome imprinting. Finally, a brief discussion of future avenues of study is highlighted.

Medical Image Processing Server applied to Quality Control of Nuclear Medicine.

NASA Astrophysics Data System (ADS)

Vergara, C.; Graffigna, J. P.; Marino, E.; Omati, S.; Holleywell, P.

2016-04-01

This paper is framed within the area of medical image processing and aims to present the process of installation, configuration and implementation of a processing server of medical images (MIPS) in the Fundación Escuela de Medicina Nuclear located in Mendoza, Argentina (FUESMEN). It has been developed in the Gabinete de Tecnologia Médica (GA.TE.ME), Facultad de Ingeniería-Universidad Nacional de San Juan. MIPS is a software that using the DICOM standard, can receive medical imaging studies of different modalities or viewing stations, then it executes algorithms and finally returns the results to other devices. To achieve the objectives previously mentioned, preliminary tests were conducted in the laboratory. More over, tools were remotely installed in clinical enviroment. The appropiate protocols for setting up and using them in different services were established once defined those suitable algorithms. Finally, it’s important to focus on the implementation and training that is provided in FUESMEN, using nuclear medicine quality control processes. Results on implementation are exposed in this work.

Multi-criteria evaluation methods in the production scheduling

NASA Astrophysics Data System (ADS)

Kalinowski, K.; Krenczyk, D.; Paprocka, I.; Kempa, W.; Grabowik, C.

2016-08-01

The paper presents a discussion on the practical application of different methods of multi-criteria evaluation in the process of scheduling in manufacturing systems. Among the methods two main groups are specified: methods based on the distance function (using metacriterion) and methods that create a Pareto set of possible solutions. The basic criteria used for scheduling were also described. The overall procedure of evaluation process in production scheduling was presented. It takes into account the actions in the whole scheduling process and human decision maker (HDM) participation. The specified HDM decisions are related to creating and editing a set of evaluation criteria, selection of multi-criteria evaluation method, interaction in the searching process, using informal criteria and making final changes in the schedule for implementation. According to need, process scheduling may be completely or partially automated. Full automatization is possible in case of metacriterion based objective function and if Pareto set is selected - the final decision has to be done by HDM.

The Integration of an Information Processing Center into a Modern Office/Word Processing Technology Course. Final Report.

ERIC Educational Resources Information Center

LeVan, Jan; Arndt, Maridene

A report and related materials are provided from an activity to set up an operating information processing center that would do the work initiated by personnel in the district and to incorporate the center into the Modern Office/Word Processing Technology course. The report details objectives, population and sample, and conclusions and…

Using Constructivist Case Study Methodology to Understand Community Development Processes: Proposed Methodological Questions to Guide the Research Process

ERIC Educational Resources Information Center

Lauckner, Heidi; Paterson, Margo; Krupa, Terry

2012-01-01

Often, research projects are presented as final products with the methodologies cleanly outlined and little attention paid to the decision-making processes that led to the chosen approach. Limited attention paid to these decision-making processes perpetuates a sense of mystery about qualitative approaches, particularly for new researchers who will…

Technological Improvements for Digital Fire Control Systems

DTIC Science & Technology

2017-09-30

Final Technical Status Report For DOTC-12-01-INIT061 Technological Improvements for Digital Fire Control Systems Reporting Period: 30 Sep...Initiative Information Develop and fabricate next generation designs using advanced materials and processes. This will include but is not limited to...4.2 Develop manufacturing processes 100% 4.3 Develop manufacturing processes 100% 4.4 Develop manufacturing processes 100% 5 Design Tooling

Validation of a 30-year-old process for the manufacture of L-asparaginase from Erwinia chrysanthemi.

PubMed

Gervais, David; Allison, Nigel; Jennings, Alan; Jones, Shane; Marks, Trevor

2013-04-01

A 30-year-old manufacturing process for the biologic product L-asparaginase from the plant pathogen Erwinia chrysanthemi was rigorously qualified and validated, with a high level of agreement between validation data and the 6-year process database. L-Asparaginase exists in its native state as a tetrameric protein and is used as a chemotherapeutic agent in the treatment regimen for Acute Lymphoblastic Leukaemia (ALL). The manufacturing process involves fermentation of the production organism, extraction and purification of the L-asparaginase to make drug substance (DS), and finally formulation and lyophilisation to generate drug product (DP). The extensive manufacturing experience with the product was used to establish ranges for all process parameters and product quality attributes. The product and in-process intermediates were rigorously characterised, and new assays, such as size-exclusion and reversed-phase UPLC, were developed, validated, and used to analyse several pre-validation batches. Finally, three prospective process validation batches were manufactured and product quality data generated using both the existing and the new analytical methods. These data demonstrated the process to be robust, highly reproducible and consistent, and the validation was successful, contributing to the granting of an FDA product license in November, 2011.

Cosmetic wastewater treatment by coagulation and advanced oxidation processes.

PubMed

Naumczyk, Jeremi; Bogacki, Jan; Marcinowski, Piotr; Kowalik, Paweł

2014-01-01

In this study, the treatment process of three cosmetic wastewater types has been investigated. Coagulation allowed to achieve chemical oxygen demand (COD) removal of 74.6%, 37.7% and 74.0% for samples A (Al2(SO4)3), B (Brentafloc F3) and C (PAX 16), respectively. The Fenton process proved to be effective as well - COD removal was equal to 75.1%, 44.7% and 68.1%, respectively. Coagulation with FeCl3 and the subsequent photo-Fenton process resulted in the best values of final COD removal equal to 92.4%, 62.8% and 90.2%. In case of the Fenton process, after coagulation these values were equal to 74.9%, 50.1% and 84.8%, while in case of the H2O2/UV process, the obtained COD removal was 83.8%, 36.2% and 80.9%. High value of COD removal in the Fenton process carried out for A and C wastewater samples was caused by a significant contribution of the final neutralization/coagulation. Very small effect of the oxidation reaction in the Fenton process in case of sample A resulting from the presence of antioxidants, 'OH radical scavengers' in the wastewater.

Implementation of hazard analysis and critical control point (HACCP) in dried anchovy production process

NASA Astrophysics Data System (ADS)

Citraresmi, A. D. P.; Wahyuni, E. E.

2018-03-01

The aim of this study was to inspect the implementation of Hazard Analysis and Critical Control Point (HACCP) for identification and prevention of potential hazards in the production process of dried anchovy at PT. Kelola Mina Laut (KML), Lobuk unit, Sumenep. Cold storage process is needed in each anchovy processing step in order to maintain its physical and chemical condition. In addition, the implementation of quality assurance system should be undertaken to maintain product quality. The research was conducted using a survey method, by following the whole process of making anchovy from the receiving raw materials to the packaging of final product. The method of data analysis used was descriptive analysis method. Implementation of HACCP at PT. KML, Lobuk unit, Sumenep was conducted by applying Pre Requisite Programs (PRP) and preparation stage consisting of 5 initial stages and 7 principles of HACCP. The results showed that CCP was found in boiling process flow with significant hazard of Listeria monocytogenesis bacteria and final sorting process with significant hazard of foreign material contamination in the product. Actions taken were controlling boiling temperature of 100 – 105°C for 3 - 5 minutes and training for sorting process employees.

[Definition and stabilization of processes II. Clinical Processes in a Urology Department].

PubMed

Pascual, Carlos; Luján, Marcos; Mora, José Ramón; Diz, Manuel Ramón; Martín, Carlos; López, María Carmen

2015-01-01

New models in clinical management seek a clinical practice based on quality, efficacy and efficiency, avoiding variability and improvisation. In this paper we have developed one of the most frequent clinical processes in our speciality, the process based on DRG 311 or transurethral procedures without complications. Along it we will describe its components: Stabilization form, clinical trajectory, cost calculation, and finally the process flowchart.

Exploration, Sampling, And Reconstruction of Free Energy Surfaces with Gaussian Process Regression.

PubMed

Mones, Letif; Bernstein, Noam; Csányi, Gábor

2016-10-11

Practical free energy reconstruction algorithms involve three separate tasks: biasing, measuring some observable, and finally reconstructing the free energy surface from those measurements. In more than one dimension, adaptive schemes make it possible to explore only relatively low lying regions of the landscape by progressively building up the bias toward the negative of the free energy surface so that free energy barriers are eliminated. Most schemes use the final bias as their best estimate of the free energy surface. We show that large gains in computational efficiency, as measured by the reduction of time to solution, can be obtained by separating the bias used for dynamics from the final free energy reconstruction itself. We find that biasing with metadynamics, measuring a free energy gradient estimator, and reconstructing using Gaussian process regression can give an order of magnitude reduction in computational cost.

An exploration in mineral supply chain mapping using tantalum as an example

USGS Publications Warehouse

Soto-Viruet, Yadira; Menzie, W. David; Papp, John F.; Yager, Thomas R.

2013-01-01

This report uses the supply chain of tantalum (Ta) to investigate the complexity of mineral and metal supply chains in general and show how they can be mapped. A supply chain is made up of all the manufacturers, suppliers, information networks, and so forth, that provide the materials and parts that go into making up a final product. The mineral portion of the supply chain begins with mineral material in the ground (the ore deposit); extends through a series of processes that include mining, beneficiation, processing (smelting and refining), semimanufacture, and manufacture; and continues through transformation of the mineral ore into concentrates, refined mineral commodities, intermediate forms (such as metals and alloys), component parts, and, finally, complex products. This study analyses the supply chain of tantalum beginning with minerals in the ground to many of the final goods that contain tantalum.

Readiness of the ATLAS Trigger and Data Acquisition system for the first LHC beams

NASA Astrophysics Data System (ADS)

Vandelli, W.; Atlas Tdaq Collaboration

2009-12-01

The ATLAS Trigger and Data Acquisition (TDAQ) system is based on O(2k) processing nodes, interconnected by a multi-layer Gigabit network, and consists of a combination of custom electronics and commercial products. In its final configuration, O(20k) applications will provide the needed capabilities in terms of event selection, data flow, local storage and data monitoring. In preparation for the first LHC beams, many TDAQ sub-systems already reached the final configuration and roughly one third of the final processing power has been deployed. Therefore, the current system allows for a sensible evaluation of the performance and scaling properties. In this paper we introduce the ATLAS TDAQ system requirements and architecture and we discuss the status of software and hardware component. We moreover present the results of performance measurements validating the system design and providing a figure for the ATLAS data acquisition capabilities in the initial data taking period.

eLaunch Hypersonics: An Advanced Launch System

NASA Technical Reports Server (NTRS)

Starr, Stanley

2010-01-01

This presentation describes a new space launch system that NASA can and should develop. This approach can significantly reduce ground processing and launch costs, improve reliability, and broaden the scope of what we do in near earth orbit. The concept (not new) is to launch a re-usable air-breathing hypersonic vehicle from a ground based electric track. This vehicle launches a final rocket stage at high altitude/velocity for the final leg to orbit. The proposal here differs from past studies in that we will launch above Mach 1.5 (above transonic pinch point) which further improves the efficiency of air breathing, horizontal take-off launch systems. The approach described here significantly reduces cost per kilogram to orbit, increases safety and reliability of the boost systems, and reduces ground costs due to horizontal-processing. Finally, this approach provides significant technology transfer benefits for our national infrastructure.

Research of Curriculum Content, Data Processing Program. Final Report.

ERIC Educational Resources Information Center

Stoehr, Keith; And Others

A study was conducted to assess the relationship between data processing competencies taught in Wisconsin Vocational, Technical, and Adult Education District Data Processing programs and on-the-job demands, as a basis for curriculum review and revision. A sample of program graduates, their employers, and instructors were asked to rate 75…

75 FR 22047 - Intent To Initiate Consultation and Coordinate the National Oceanic and Atmospheric...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-27

... purposes and policies of the NMSA (73 FR 53161). The management plan review process occurs concurrently... management plan was written as part of the sanctuary designation process and published in the Final... Environmental Impact Statement under the authority of NEPA (73 FR 53161). The management plan review process is...

Data Input, Processing and Presentation. [helicopter rotor balance measurement

NASA Technical Reports Server (NTRS)

Langer, H. J.

1984-01-01

The problems of data acquisition, processing and display are investigated in the case of a helicopter rotor balance. The types of sensors to be employed are discussed in addition to their placement and application in wind tunnel trials. Finally, the equipment for data processing, evaluation and storage are presented with a description of methods.

An Evaluation of the Decennial Review Process.

ERIC Educational Resources Information Center

Barak, Robert; And Others

Information on a review of the decennial review process required by the Arizona Board of Regents (ABOR) for every academic department in each Arizona university is presented as part of the final report by ABOR's Task Force on Excellence, Efficiency and Competitiveness. Revision in the review process and eight policy statements are discussed, and…

The Development of Reading for Comprehension: An Information Processing Analysis. Final Report.

ERIC Educational Resources Information Center

Schadler, Margaret; Juola, James F.

This report summarizes research performed at the Universtiy of Kansas that involved several topics related to reading and learning to read, including the development of automatic word recognition processes, reading for comprehension, and the development of new computer technologies designed to facilitate the reading process. The first section…

76 FR 53763 - Immigration Benefits Business Transformation, Increment I

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-29

...The Department of Homeland Security (DHS) is amending its regulations to enable U.S. Citizenship and Immigration Services (USCIS) to migrate from a paper file-based, non-integrated systems environment to an electronic customer-focused, centralized case management environment for benefit processing. This transformation process will allow USCIS to streamline benefit processing, eliminate the capture and processing of redundant data, and reduce the number of and automate its forms. This transformation process will be a phased multi-year initiative to restructure USCIS business processes and related information technology systems. DHS is removing references to form numbers, form titles, expired regulatory provisions, and descriptions of internal procedures, many of which will change during transformation. DHS is also finalizing interim rules that permitted submission of benefit requests with an electronic signature when such requests are submitted in an electronic format rather than on a paper form and that removed references to filing locations for immigration benefits. In addition, in this rule DHS is publishing the final rule for six other interim rules published during the past several years, most of which received no public comments.

Leading-process actomyosin coordinates organelle positioning and adhesion receptor dynamics in radially migrating cerebellar granule neurons

DOE PAGES

Trivedi, Niraj; Ramahi, Joseph S.; Karakaya, Mahmut; ...

2014-12-02

During brain development, neurons migrate from germinal zones to their final positions to assemble neural circuits. A unique saltatory cadence involving cyclical organelle movement (e.g., centrosome motility) and leading-process actomyosin enrichment prior to nucleokinesis organizes neuronal migration. While functional evidence suggests that leading-process actomyosin is essential for centrosome motility, the role of the actin-enriched leading process in globally organizing organelle transport or traction forces remains unexplored. Our results show that myosin ii motors and F-actin dynamics are required for Golgi apparatus positioning before nucleokinesis in cerebellar granule neurons (CGNs) migrating along glial fibers. Moreover, we show that primary cilia aremore » motile organelles, localized to the leading-process F-actin-rich domain and immobilized by pharmacological inhibition of myosin ii and F-actin dynamics. Finally, leading process adhesion dynamics are dependent on myosin ii and F-actin. In conclusion, we propose that actomyosin coordinates the overall polarity of migrating CGNs by controlling asymmetric organelle positioning and cell-cell contacts as these cells move along their glial guides.« less

Leading-process actomyosin coordinates organelle positioning and adhesion receptor dynamics in radially migrating cerebellar granule neurons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Trivedi, Niraj; Ramahi, Joseph S.; Karakaya, Mahmut

During brain development, neurons migrate from germinal zones to their final positions to assemble neural circuits. A unique saltatory cadence involving cyclical organelle movement (e.g., centrosome motility) and leading-process actomyosin enrichment prior to nucleokinesis organizes neuronal migration. While functional evidence suggests that leading-process actomyosin is essential for centrosome motility, the role of the actin-enriched leading process in globally organizing organelle transport or traction forces remains unexplored. Our results show that myosin ii motors and F-actin dynamics are required for Golgi apparatus positioning before nucleokinesis in cerebellar granule neurons (CGNs) migrating along glial fibers. Moreover, we show that primary cilia aremore » motile organelles, localized to the leading-process F-actin-rich domain and immobilized by pharmacological inhibition of myosin ii and F-actin dynamics. Finally, leading process adhesion dynamics are dependent on myosin ii and F-actin. In conclusion, we propose that actomyosin coordinates the overall polarity of migrating CGNs by controlling asymmetric organelle positioning and cell-cell contacts as these cells move along their glial guides.« less

MINING AND PROCESSING AT THE MARY KATHLEEN

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1959-03-01

Ore mining and processing to the yellow cake at Mary Kathleen, Queensland, Australia, are described. The mining, crushlng, grinding, leaching, solids separation, ion exchange, purification, and final precipitation procedures and equipment are discussed in some detail. (T.R.H.)

Rockfall Hazard Process Assessment : Final Project Report

DOT National Transportation Integrated Search

2017-10-01

After a decade of using the Rockfall Hazard Rating System (RHRS), the Montana Department of Transportation (MDT) sought a reassessment of their rockfall hazard evaluation process. Their prior system was a slightly modified version of the RHRS and was...

Least-cost transportation planning in ODOT : phase 2 final report.

DOT National Transportation Integrated Search

1996-06-01

This project is intended to suggest ways in which least-cost planning principles could be incorporated into the transportation planning process. The Mt. Hood corridor was chosen for examination. The examination of the planning process highlighted sev...

Integrating intelligent transportation systems within the transportation planning process : an interim handbook.

DOT National Transportation Integrated Search

1998-01-01

The Final Rule on Statewide Planning and Metropolitan Planning issued by the Federal Highway Administration (FHWA) and Federal Transit Administration (FTA) in October, 1993 established revised and more comprehensive processes for metropolitan and sta...

78 FR 57273 - Approval and Promulgation of Air Quality Implementation Plans; Ohio; Redesignation of the...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-18

... chemical reactions or other processes in the atmosphere. \\2\\ NO X and SO 2 are precursors for fine particulates through chemical reactions and other related processes in the atmosphere. Finally, EPA is...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sjöstrand, Torbjörn; Ask, Stefan; Christiansen, Jesper R.

The Pythia program is a standard tool for the generation of events in high-energy collisions, comprising a coherent set of physics models for the evolution from a few-body hard process to a complex multiparticle final state. It contains a library of hard processes, models for initial- and final-state parton showers, matching and merging methods between hard processes and parton showers, multiparton interactions, beam remnants, string fragmentation and particle decays. It also has a set of utilities and several interfaces to external programs. Pythia 8.2 is the second main release after the complete rewrite from Fortran to C++, and now hasmore » reached such a maturity that it offers a complete replacement for most applications, notably for LHC physics studies. Lastly, the many new features should allow an improved description of data.« less

Evidence of Coherent K+ Meson Production in Neutrino-Nucleus Scattering

NASA Astrophysics Data System (ADS)

Wang, Z.; Marshall, C. M.; Aliaga, L.; Altinok, O.; Bellantoni, L.; Bercellie, A.; Betancourt, M.; Bodek, A.; Bravar, A.; Budd, H.; Cai, T.; Carneiro, M. F.; da Motta, H.; Dytman, S. A.; Díaz, G. A.; Eberly, B.; Endress, E.; Felix, J.; Fields, L.; Fine, R.; Galindo, R.; Gallagher, H.; Ghosh, A.; Golan, T.; Gran, R.; Harris, D. A.; Higuera, A.; Hurtado, K.; Kiveni, M.; Kleykamp, J.; Kordosky, M.; Le, T.; Maher, E.; Manly, S.; Mann, W. A.; Martinez Caicedo, D. A.; McFarland, K. S.; McGivern, C. L.; McGowan, A. M.; Messerly, B.; Miller, J.; Mislivec, A.; Morfín, J. G.; Mousseau, J.; Naples, D.; Nelson, J. K.; Norrick, A.; Nuruzzaman; Paolone, V.; Park, J.; Patrick, C. E.; Perdue, G. N.; Rakotondravohitra, L.; Ramirez, M. A.; Ransome, R. D.; Ray, H.; Ren, L.; Rimal, D.; Rodrigues, P. A.; Ruterbories, D.; Schellman, H.; Schmitz, D. W.; Simon, C.; Solano Salinas, C. J.; Tice, B. G.; Valencia, E.; Walton, T.; Wolcott, J.; Wospakrik, M.; Zavala, G.; Zhang, D.; Minerva Collaboration

2016-08-01

Neutrino-induced charged-current coherent kaon production νμA →μ-K+A is a rare, inelastic electroweak process that brings a K+ on shell and leaves the target nucleus intact in its ground state. This process is significantly lower in rate than the neutrino-induced charged-current coherent pion production because of Cabibbo suppression and a kinematic suppression due to the larger kaon mass. We search for such events in the scintillator tracker of MINERvA by observing the final state K+, μ-, and no other detector activity, and by using the kinematics of the final state particles to reconstruct the small momentum transfer to the nucleus, which is a model-independent characteristic of coherent scattering. We find the first experimental evidence for the process at 3 σ significance.

KSC-2009-2308

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – The NASA Railroad hauls one of the cars with the first Ares I-X segment to the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida. Four reusable motor segments and the nozzle exit cone, manufactured by the Ares I first-stage prime contractor Alliant Techsystems Inc., departed Utah March 12 on the seven-day, cross-country trip to Florida. The segments are being delivered to Kennedy's Rotation, Processing and Surge Facility for final processing and integration. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming test flight this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jack Pfaller

KSC-2009-2307

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – The NASA Railroad hauls one of the cars with the first Ares I-X segment to the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida. Four reusable motor segments and the nozzle exit cone, manufactured by the Ares I first-stage prime contractor Alliant Techsystems Inc., departed Utah March 12 on the seven-day, cross-country trip to Florida. The segments are being delivered to Kennedy's Rotation, Processing and Surge Facility for final processing and integration. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming test flight this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jack Pfaller

KSC-2009-2310

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – The NASA Railroad delivers the first Ares I-X segment to the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida. Four reusable motor segments and the nozzle exit cone, manufactured by the Ares I first-stage prime contractor Alliant Techsystems Inc., departed Utah March 12 on the seven-day, cross-country trip to Florida. The segments are being delivered to Kennedy's Rotation, Processing and Surge Facility for final processing and integration. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming test flight this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jack Pfaller

KSC-2009-2309

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – The NASA Railroad delivers the first Ares I-X segment to the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida. Four reusable motor segments and the nozzle exit cone, manufactured by the Ares I first-stage prime contractor Alliant Techsystems Inc., departed Utah March 12 on the seven-day, cross-country trip to Florida. The segments are being delivered to Kennedy's Rotation, Processing and Surge Facility for final processing and integration. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming test flight this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jack Pfaller

Piling-to-buckling transition in the drying process of polymer solution drop on substrate having a large contact angle.

PubMed

Kajiya, Tadashi; Nishitani, Eisuke; Yamaue, Tatsuya; Doi, Masao

2006-01-01

We studied the drying process of polymer solution drops placed on a substrate having a large contact angle with the drop. The drying process takes place in three stages. First, the droplet evaporates keeping the contact line fixed. Second, the droplet shrinks uniformly with receding contact line. Finally the contact line is pinned again, and the droplet starts to be deformed. The shape of the final polymer deposit changes from concave dot, to flat dot, and then to concave dot again with the increase of the initial polymer concentration. This shape change is caused by the gradual transition from the solute piling mechanism proposed by Deegan to the crust buckling mechanism proposed by de Gennes and Pauchard.

Microbial Performance of Food Safety Control and Assurance Activities in a Fresh Produce Processing Sector Measured Using a Microbial Assessment Scheme and Statistical Modeling.

PubMed

Njage, Patrick Murigu Kamau; Sawe, Chemutai Tonui; Onyango, Cecilia Moraa; Habib, I; Njagi, Edmund Njeru; Aerts, Marc; Molenberghs, Geert

2017-01-01

Current approaches such as inspections, audits, and end product testing cannot detect the distribution and dynamics of microbial contamination. Despite the implementation of current food safety management systems, foodborne outbreaks linked to fresh produce continue to be reported. A microbial assessment scheme and statistical modeling were used to systematically assess the microbial performance of core control and assurance activities in five Kenyan fresh produce processing and export companies. Generalized linear mixed models and correlated random-effects joint models for multivariate clustered data followed by empirical Bayes estimates enabled the analysis of the probability of contamination across critical sampling locations (CSLs) and factories as a random effect. Salmonella spp. and Listeria monocytogenes were not detected in the final products. However, none of the processors attained the maximum safety level for environmental samples. Escherichia coli was detected in five of the six CSLs, including the final product. Among the processing-environment samples, the hand or glove swabs of personnel revealed a higher level of predicted contamination with E. coli , and 80% of the factories were E. coli positive at this CSL. End products showed higher predicted probabilities of having the lowest level of food safety compared with raw materials. The final products were E. coli positive despite the raw materials being E. coli negative for 60% of the processors. There was a higher probability of contamination with coliforms in water at the inlet than in the final rinse water. Four (80%) of the five assessed processors had poor to unacceptable counts of Enterobacteriaceae on processing surfaces. Personnel-, equipment-, and product-related hygiene measures to improve the performance of preventive and intervention measures are recommended.

Automated Production of Movies on a Cluster of Computers

NASA Technical Reports Server (NTRS)

Nail, Jasper; Le, Duong; Nail, William L.; Nail, William

2008-01-01

A method of accelerating and facilitating production of video and film motion-picture products, and software and generic designs of computer hardware to implement the method, are undergoing development. The method provides for automation of most of the tedious and repetitive tasks involved in editing and otherwise processing raw digitized imagery into final motion-picture products. The method was conceived to satisfy requirements, in industrial and scientific testing, for rapid processing of multiple streams of simultaneously captured raw video imagery into documentation in the form of edited video imagery and video derived data products for technical review and analysis. In the production of such video technical documentation, unlike in production of motion-picture products for entertainment, (1) it is often necessary to produce multiple video derived data products, (2) there are usually no second chances to repeat acquisition of raw imagery, (3) it is often desired to produce final products within minutes rather than hours, days, or months, and (4) consistency and quality, rather than aesthetics, are the primary criteria for judging the products. In the present method, the workflow has both serial and parallel aspects: processing can begin before all the raw imagery has been acquired, each video stream can be subjected to different stages of processing simultaneously on different computers that may be grouped into one or more cluster(s), and the final product may consist of multiple video streams. Results of processing on different computers are shared, so that workers can collaborate effectively.

75 FR 71353 - Office of the Attorney General; Certification Process for State Capital Counsel Systems; Removal...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-23

... DEPARTMENT OF JUSTICE 28 CFR Part 26 [Docket No. OJP 1464; AG Order No.] RIN 1121-AA76 Office of... AGENCY: Department of Justice. ACTION: Final rule. SUMMARY: Pursuant to the USA PATRIOT Improvement and Reauthorization Act of 2005, the Department of Justice promulgated a final rule to implement certification...

78 FR 7137 - National Emission Standards for Hazardous Air Pollutants for Major Sources: Industrial...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-31

... 2011 final rule was, therefore, in effect until publication of this action. Summary of Major... economy this final rule effects, the EPA is revising certain subcategories for boilers and process heaters...,000 to $59,000. Non-monetized Benefits Health effects from exposure to HAP (39,000 tons of HCl, 500...

76 FR 53057 - Change to the Reporting Date for Certain Data Elements Required Under the Mandatory Reporting of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-25

..., blast furnaces, basic oxygen process furnace shops. Lead Production 331419 Primary lead smelting and.... Chapter 5, generally provides that rules may not take effect earlier than 30 days after they are published... behavior and prepare before the final rule takes effect. Because this final rule defers a reporting...

25 CFR 115.615 - How long after the hearing will BIA make its final decision?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 1 2013-04-01 2013-04-01 false How long after the hearing will BIA make its final decision? 115.615 Section 115.615 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES TRUST FUNDS FOR TRIBES AND INDIVIDUAL INDIANS IIM Accounts: Hearing Process for Restricting an IIM...

25 CFR 115.615 - How long after the hearing will BIA make its final decision?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 1 2011-04-01 2011-04-01 false How long after the hearing will BIA make its final decision? 115.615 Section 115.615 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES TRUST FUNDS FOR TRIBES AND INDIVIDUAL INDIANS IIM Accounts: Hearing Process for Restricting an IIM...

25 CFR 115.615 - How long after the hearing will BIA make its final decision?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false How long after the hearing will BIA make its final decision? 115.615 Section 115.615 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES TRUST FUNDS FOR TRIBES AND INDIVIDUAL INDIANS IIM Accounts: Hearing Process for Restricting an IIM...

25 CFR 115.615 - How long after the hearing will BIA make its final decision?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 1 2012-04-01 2011-04-01 true How long after the hearing will BIA make its final decision? 115.615 Section 115.615 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES TRUST FUNDS FOR TRIBES AND INDIVIDUAL INDIANS IIM Accounts: Hearing Process for Restricting an IIM...

25 CFR 115.615 - How long after the hearing will BIA make its final decision?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 1 2014-04-01 2014-04-01 false How long after the hearing will BIA make its final decision? 115.615 Section 115.615 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES TRUST FUNDS FOR TRIBES AND INDIVIDUAL INDIANS IIM Accounts: Hearing Process for Restricting an IIM...

75 FR 78978 - Record of Decision for the 158th Fighter Wing's Proposed Realignment of National Guard Avenue and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-17

... resources and personnel). The decision was based on matters discussed in the Final Environmental Impact... from the public and regulatory agencies, and other relevant factors. The Final EIS was made available... NEPA of 1969 (42 USC. 4321, et seq.) and the Air Force's Environmental Impact Analysis Process (EIAP...

Phase B: Final definition and preliminary design study for the initial Atmospheric Cloud Physics Laboratory (ACPL): A spacelab mission payload. Final review (DR-MA-03)

NASA Technical Reports Server (NTRS)

Clausen, O. W.

1976-01-01

Systems design for an initial atmospheric cloud physics laboratory to study microphysical processes in zero gravity is presented. Included are descriptions of the fluid, thermal, mechanical, control and data, and electrical distribution interfaces with Spacelab. Schedule and cost analysis are discussed.

The Elder Abuse Prevention Project, Phase Two, Three and Four. Final Report.

ERIC Educational Resources Information Center

Regina Univ. (Saskatchewan). Univ. Extension. Seniors Education Centre.

This document presents the final report from an educational and community development program designed to raise awareness about the abuse and neglect of the elderly. The Elder Abuse Prevention Project is briefly described in terms of project goals, objectives, the model used, the target groups served, and the evaluation processes employed. It is…

a New Animation of Subduction Processes for Undergraduates

NASA Astrophysics Data System (ADS)

Stern, R. J.; Lieu, W. K.; Mantey, A.; Ward, A.; Todd, F.; Farrar, E.; Sean, M.; Windler, J.

2015-12-01

The subduction of oceanic lithosphere beneath convergent plate margins is a fundamental plate tectonic concept and an important Earth process. It is responsible for some of Earth's most dangerous natural hazards including earthquakes and volcanic eruptions but also produced the continental crust and important mineral deposits. A range of geoscientific efforts including NSF MARGINS and GeoPRISMS initiatives have advanced our understanding of subduction zone processes. In spite the importance of subduction zones and our advancing understanding of how these function, there are few animations that clearly explain the subduction process to non-expert audiences. This deficiency reflects the disparate expertises between geoscientists who know the science but have weak animation skills and digital artists and animators who have strong skills in showing objects in motion but are not experts in natural processes like plate tectonics. This transdisciplinary gap can and should be bridged. With a small grant from NSF (DUE-1444954) we set about to generate a realistic subduction zone animation aimed at the university undergraduate audience by first working within our university to rough out a draft animation and then contract a professional to use this to construct the final version. UTD Geosciences faculty (Stern) and graduate student (Lieu) teamed up with faculty from UTD School of Arts, Technology, and Emerging Communication (ATEC)(Farrar, Fechter, and McComber) to identify and recruit talented ATEC undergraduate students (Mantey, Ward) to work on the project. Geoscientists assembled a storyboard and met weekly with ATEC undergraduates to generate a first draft of the animation, which guided development of an accompanying narrative. The draft animation with voice-over was then handed off to professional animator Windler (Archistration CG) to generate the final animation. We plan to show both the student-generated draft version and the final animation during our presentation. The final animation will be freely available via the internet and will also be used as a supplement for McGraw-Hill textbooks in oceanography, physical geology, Earth science, geography, historical geology, natural hazards, and natural resources.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eun, H.C.; Cho, Y.Z.; Choi, J.H.

A regeneration process of LiCl-KCl eutectic waste salt generated from the pyrochemical process of spent nuclear fuel has been studied. This regeneration process is composed of a chemical conversion process and a vacuum distillation process. Through the regeneration process, a high efficiency of renewable salt recovery can be obtained from the waste salt and rare earth nuclides in the waste salt can be separated as oxide or phosphate forms. Thus, the regeneration process can contribute greatly to a reduction of the waste volume and a creation of durable final waste forms. (authors)

Development of environmentally conscious cleaning process for leadless chip carrier assemblies. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adams, B.E.

1995-04-01

A cross-functional team of process, product, quality, material, and design lab engineers was assembled to develop an environmentally friendly cleaning process for leadless chip carrier assemblies (LCCAs). Using flush and filter testing, Auger surface analysis, GC-Mass spectrophotometry, production yield results, and electrical testing results over an extended testing period, the team developed an aqueous cleaning process for LCCAs. The aqueous process replaced the Freon vapor degreasing/ultrasonic rinse process.

Comparative Effects of Antihistamines on Aircrew Mission Effectiveness under Sustained Operations

DTIC Science & Technology

1992-06-01

measures consist mainly of process measures. Process measures are measures of activities used to accomplish the mission and produce the final results...They include task completion times and response variability, and information processing rates as they relate to unique task assignment. Performance...contains process measures that assess the Individual contributions of hardware/software and human components to overall system performance. Measures

Teaching Electrostatics in University Courses

ERIC Educational Resources Information Center

Hughes, J. F.

1974-01-01

Describes an optional course on applied electrostatics that was offered to electrical engineers in their final year. Topics included the determination of electric fields, nature of the charging process, static electricity in liquids, solid state processes, charged particle applications, and electrostatic ignition. (GS)

The prioritization of mobility improvements using a multicriteria prioritization algorithm : final report

DOT National Transportation Integrated Search

1998-07-01

A prioritization process has been prepared by the University of California, Davis, for use by the Oregon Department of Transportation (ODOT) in selecting multimodal mobility improvement projects to fund, given a budget constraint. The process involve...

39 CFR 3050.24 - Documentation supporting estimates of costs avoided by worksharing and other mail characteristics...

Code of Federal Regulations, 2010 CFR

2010-07-01

... Computer Reader finalization costs, cost per image, and Remote Bar Code Sorter leakage; (8) Percentage of... processing units costs for Carrier Route, High Density, and Saturation mail; (j) Mail processing unit costs...

39 CFR 3050.24 - Documentation supporting estimates of costs avoided by worksharing and other mail characteristics...

Code of Federal Regulations, 2011 CFR

2011-07-01

... Computer Reader finalization costs, cost per image, and Remote Bar Code Sorter leakage; (8) Percentage of... processing units costs for Carrier Route, High Density, and Saturation mail; (j) Mail processing unit costs...

39 CFR 3050.24 - Documentation supporting estimates of costs avoided by worksharing and other mail characteristics...

Code of Federal Regulations, 2013 CFR

2013-07-01

... Computer Reader finalization costs, cost per image, and Remote Bar Code Sorter leakage; (8) Percentage of... processing units costs for Carrier Route, High Density, and Saturation mail; (j) Mail processing unit costs...

39 CFR 3050.24 - Documentation supporting estimates of costs avoided by worksharing and other mail characteristics...

Code of Federal Regulations, 2014 CFR

2014-07-01

... Computer Reader finalization costs, cost per image, and Remote Bar Code Sorter leakage; (8) Percentage of... processing units costs for Carrier Route, High Density, and Saturation mail; (j) Mail processing unit costs...

39 CFR 3050.24 - Documentation supporting estimates of costs avoided by worksharing and other mail characteristics...

Code of Federal Regulations, 2012 CFR

2012-07-01

... Computer Reader finalization costs, cost per image, and Remote Bar Code Sorter leakage; (8) Percentage of... processing units costs for Carrier Route, High Density, and Saturation mail; (j) Mail processing unit costs...

Optimum Design of Forging Process Parameters and Preform Shape under Uncertainties

NASA Astrophysics Data System (ADS)

Repalle, Jalaja; Grandhi, Ramana V.

2004-06-01

Forging is a highly complex non-linear process that is vulnerable to various uncertainties, such as variations in billet geometry, die temperature, material properties, workpiece and forging equipment positional errors and process parameters. A combination of these uncertainties could induce heavy manufacturing losses through premature die failure, final part geometric distortion and production risk. Identifying the sources of uncertainties, quantifying and controlling them will reduce risk in the manufacturing environment, which will minimize the overall cost of production. In this paper, various uncertainties that affect forging tool life and preform design are identified, and their cumulative effect on the forging process is evaluated. Since the forging process simulation is computationally intensive, the response surface approach is used to reduce time by establishing a relationship between the system performance and the critical process design parameters. Variability in system performance due to randomness in the parameters is computed by applying Monte Carlo Simulations (MCS) on generated Response Surface Models (RSM). Finally, a Robust Methodology is developed to optimize forging process parameters and preform shape. The developed method is demonstrated by applying it to an axisymmetric H-cross section disk forging to improve the product quality and robustness.

Combining microwave resonance technology to multivariate data analysis as a novel PAT tool to improve process understanding in fluid bed granulation.

PubMed

Lourenço, Vera; Herdling, Thorsten; Reich, Gabriele; Menezes, José C; Lochmann, Dirk

2011-08-01

A set of 192 fluid bed granulation batches at industrial scale were in-line monitored using microwave resonance technology (MRT) to determine moisture, temperature and density of the granules. Multivariate data analysis techniques such as multiway partial least squares (PLS), multiway principal component analysis (PCA) and multivariate batch control charts were applied onto collected batch data sets. The combination of all these techniques, along with off-line particle size measurements, led to significantly increased process understanding. A seasonality effect could be put into evidence that impacted further processing through its influence on the final granule size. Moreover, it was demonstrated by means of a PLS that a relation between the particle size and the MRT measurements can be quantitatively defined, highlighting a potential ability of the MRT sensor to predict information about the final granule size. This study has contributed to improve a fluid bed granulation process, and the process knowledge obtained shows that the product quality can be built in process design, following Quality by Design (QbD) and Process Analytical Technology (PAT) principles. Copyright © 2011. Published by Elsevier B.V.

Evaluation of the Removal of Indicator Bacteria from Domestic Sludge Processed by Autothermal Thermophilic Aerobic Digestion (ATAD)

PubMed Central

Piterina, Anna V.; Bartlett, John; Pembroke, Tony J.

2010-01-01

The degradation of sludge solids in an insulated reactor during Autothermal Thermophilic Aerobic Digestion (ATAD) processing results in auto-heating, thermal treatment and total solids reduction, however, the ability to eliminate pathogenic organisms has not been analysed under large scale process conditions. We evaluated the ATAD process over a period of one year in a two stage, full scale Irish ATAD plant established in Killarney and treating mixed primary and secondary sludge, by examining the sludge microbiologically at various stages during and following ATAD processing to determine its ability to eliminate indicator organisms. Salmonella spp. (pathogen) and fecal-coliform (indicator) densities were well below the limits used to validate class A biosolids in the final product. Enteric pathogens present at inlet were deactivated during the ATAD process and were not detected in the final product using both traditional microbial culture and molecular phylogenetic techniques. A high DNase activity was detected in the bulk sludge during the thermophilic digestion stage which may be responsible for the rapid turn over of DNA from lysed cells and the removal of mobile DNA. These results offer assurance for the safe use of ATAD sludge as a soil supplement following processing. PMID:20948933

Evaluation of the removal of indicator bacteria from domestic sludge processed by Autothermal Thermophilic Aerobic Digestion (ATAD).

PubMed

Piterina, Anna V; Bartlett, John; Pembroke, Tony J

2010-09-01

The degradation of sludge solids in an insulated reactor during Autothermal Thermophilic Aerobic Digestion (ATAD) processing results in auto-heating, thermal treatment and total solids reduction, however, the ability to eliminate pathogenic organisms has not been analysed under large scale process conditions. We evaluated the ATAD process over a period of one year in a two stage, full scale Irish ATAD plant established in Killarney and treating mixed primary and secondary sludge, by examining the sludge microbiologically at various stages during and following ATAD processing to determine its ability to eliminate indicator organisms. Salmonella spp. (pathogen) and fecal-coliform (indicator) densities were well below the limits used to validate class A biosolids in the final product. Enteric pathogens present at inlet were deactivated during the ATAD process and were not detected in the final product using both traditional microbial culture and molecular phylogenetic techniques. A high DNase activity was detected in the bulk sludge during the thermophilic digestion stage which may be responsible for the rapid turn over of DNA from lysed cells and the removal of mobile DNA. These results offer assurance for the safe use of ATAD sludge as a soil supplement following processing.

Fabrication development for high-level nuclear waste containers for the tuff repository; Phase 1 final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Domian, H.A.; Holbrook, R.L.; LaCount, D.F.

1990-09-01

This final report completes Phase 1 of an engineering study of potential manufacturing processes for the fabrication of containers for the long-term storage of nuclear waste. An extensive literature and industry review was conducted to identify and characterize various processes. A technical specification was prepared using the American Society of Mechanical Engineers Boiler & Pressure Vessel Code (ASME BPVC) to develop the requirements. A complex weighting and evaluation system was devised as a preliminary method to assess the processes. The system takes into account the likelihood and severity of each possible failure mechanism in service and the effects of variousmore » processes on the microstructural features. It is concluded that an integral, seamless lower unit of the container made by back extrusion has potential performance advantages but is also very high in cost. A welded construction offers lower cost and may be adequate for the application. Recommendations are made for the processes to be further evaluated in the next phase when mock-up trials will be conducted to address key concerns with various processes and materials before selecting a primary manufacturing process. 43 refs., 26 figs., 34 tabs.« less

Business Process Improvement Applied to Written Temporary Duty Travel Orders within the United States Air Force

DTIC Science & Technology

1993-12-01

Generally Accepted Process While neither DoD Directives nor USAF Regulations specify exact mandatory TDY order processing methods, most USAF units...functional input. Finally, TDY order processing functional experts at Hanscom, Los Angeles and McClellan AFBs provided inputs based on their experiences...current electronic auditing capabilities. 81 DTPS Initiative. This DFAS-initiated action to standardize TDY order processing throughout DoD is currently

Some opinions on the review process of research papers destined for publication.

PubMed

Roohi, Ehsan; Mahian, Omid

2015-06-01

The current paper discusses the peer review process in journals that publish research papers purveying new science and understandings (scientific journals). Different aspects of peer review including the selection of reviewers, the review process and the decision policy of editor are discussed in details. Here, the pros and cons of different conventional methods of review processes are mentioned. Finally, a suggestion is presented for the review process of scientific papers.

Quality-by-Design approach to monitor the operation of a batch bioreactor in an industrial avian vaccine manufacturing process.

PubMed

Largoni, Martina; Facco, Pierantonio; Bernini, Donatella; Bezzo, Fabrizio; Barolo, Massimiliano

2015-10-10

Monitoring batch bioreactors is a complex task, due to the fact that several sources of variability can affect a running batch and impact on the final product quality. Additionally, the product quality itself may not be measurable on line, but requires sampling and lab analysis taking several days to be completed. In this study we show that, by using appropriate process analytical technology tools, the operation of an industrial batch bioreactor used in avian vaccine manufacturing can be effectively monitored as the batch progresses. Multivariate statistical models are built from historical databases of batches already completed, and they are used to enable the real time identification of the variability sources, to reliably predict the final product quality, and to improve process understanding, paving the way to a reduction of final product rejections, as well as to a reduction of the product cycle time. It is also shown that the product quality "builds up" mainly during the first half of a batch, suggesting on the one side that reducing the variability during this period is crucial, and on the other side that the batch length can possibly be shortened. Overall, the study demonstrates that, by using a Quality-by-Design approach centered on the appropriate use of mathematical modeling, quality can indeed be built "by design" into the final product, whereas the role of end-point product testing can progressively reduce its importance in product manufacturing. Copyright © 2015 Elsevier B.V. All rights reserved.

Operations research methods improve chemotherapy patient appointment scheduling.

PubMed

Santibáñez, Pablo; Aristizabal, Ruben; Puterman, Martin L; Chow, Vincent S; Huang, Wenhai; Kollmannsberger, Christian; Nordin, Travis; Runzer, Nancy; Tyldesley, Scott

2012-12-01

Clinical complexity, scheduling restrictions, and outdated manual booking processes resulted in frequent clerical rework, long waitlists for treatment, and late appointment notification for patients at a chemotherapy clinic in a large cancer center in British Columbia, Canada. A 17-month study was conducted to address booking, scheduling and workload issues and to develop, implement, and evaluate solutions. A review of scheduling practices included process observation and mapping, analysis of historical appointment data, creation of a new performance metric (final appointment notification lead time), and a baseline patient satisfaction survey. Process improvement involved discrete event simulation to evaluate alternative booking practice scenarios, development of an optimization-based scheduling tool to improve scheduling efficiency, and change management for implementation of process changes. Results were evaluated through analysis of appointment data, a follow-up patient survey, and staff surveys. Process review revealed a two-stage scheduling process. Long waitlists and late notification resulted from an inflexible first-stage process. The second-stage process was time consuming and tedious. After a revised, more flexible first-stage process and an automated second-stage process were implemented, the median percentage of appointments exceeding the final appointment notification lead time target of one week was reduced by 57% and median waitlist size decreased by 83%. Patient surveys confirmed increased satisfaction while staff feedback reported reduced stress levels. Significant operational improvements can be achieved through process redesign combined with operations research methods.

KSC-2009-2311

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – The first Ares I-X motor segment is in the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

Crystallization processes in pharmaceutical technology and drug delivery design

NASA Astrophysics Data System (ADS)

Shekunov, B. Yu; York, P.

2000-04-01

Crystallization is a major technological process for particle formation in pharmaceutical industry and, in addition, plays an important role in defining the stability and drug release properties of the final dosage forms. Industrial and regulatory aspects of crystallization are briefly reviewed with reference to solid-state properties of pharmaceuticals. Crystallization, incorporating wider definition to include precipitation and solid-state transitions, is considered in terms of preparation of materials for direct compression, formation of amorphous, solvated and polymorphic forms, chiral separation of drugs, production of materials for inhalation drug delivery and injections. Finally, recent developments in supercritical fluid particle technology is considered in relationship to the areas discussed.

Extension of Effective Date for Temporary Pilot Program Setting the Time and Place for a Hearing Before an Administrative Law Judge. Final rule.

PubMed

2015-07-02

We are extending for one year our pilot program that authorizes the agency to set the time and place for a hearing before an administrative law judge (ALJ). Extending of the pilot program continues our commitment to improve the efficiency of our hearing process and to maintain a hearing process that results in accurate, high-quality decisions for claimants. The current pilot program will expire on August 10, 2015. In this final rule, we are extending the effective date to August 12, 2016. We are making no other substantive changes.

Creating a dashboard to track progress toward IOM recommendations for the future of nursing.

PubMed

Spetz, Joanne; Bates, Timothy; Chu, Lela; Lin, Jessica; Fishman, Nancy W; Melichar, Lori

2013-01-01

This article explains the process used to identify and develop a set of data used to track national progress toward the recommendations of the Institute of Medicine Committee for the Future of Nursing. The data are presented in a dashboard format to visually summarize information and quickly measure progress. The approach selected by the research team is outlined, the criteria for selecting candidate metrics are detailed, the process for seeking external guidance is described, and the final dashboard measures are presented. Finally, the methods for data collection for each metric are explicated, to guide states and local regions in the collection of their own data.

Liquid-feed flame spray pyrolysis synthesis of oxide nanopowders for the processing of ceramic composites

NASA Astrophysics Data System (ADS)

Taylor, Nathan John

In the liquid-feed flame spray pyrolysis (LF-FSP) process, alcohol solutions of metalloorganic precursors are aerosolized by O2 and combusted. The metal oxide combustion products are rapidly quenched (< 10 ms) from flame temperatures of 1500°C to temperatures < 400° C, limiting particle growth. The resulting nanopowders are typically agglomerated but unaggregated. Here, we demonstrate two processing approaches to dense materials: nanopowders with the exact composition, and mixed single metal oxide nanopowders. The effect of the initial degree of phase separation on the final microstructures was determined by sintering studies. Our first studies included the production of yttrium aluminum garnet, Y3Al5O12 (YAG), tubes which we extruded from a thermoplastic/ceramic blend. At equivalent final densities, we found finer grain sizes in the from the mixed Y2O3 and Al2 O3 nanopowders, which was attributed to densification occurring before full transformation to the YAG phase. The enhanced densification in production of pure YAG from the reactive sintering process led us to produce composites in the YAG/alpha-Al 2O3 system. Finally, a third Y2O3 stabilized ZrO2 (YSZ) phase was added to further refine grain sizes using the same two processing approaches. In a separate study, single-phase metastable Al2O3 rich spinels with the composition MO•3Al 2O3 where M = Mg, Ni, and Co were sintered to produce dense MAl2O4/alpha-Al2O3 composites. All of these studies provide a test of the bottom-up approach; that is, how the initial length scale of mixing affects the final composite microstructure. Overall, the length scale of mixing is highly dependent upon the specific oxide composites studied. This work provides a processing framework to be adopted by other researchers to further refine microstructural size. LF-FSP flame temperatures were mapped using different alcohols with different heats of combustion: methanol, ethanol, 1-propanol, and n-butanol. The effect of different alcohols on particle size and phase was determined through studies on Al2O3, Y2O3 and TiO2 nanopowders. The final studies describe the morphology of composite nanopowders produced in the WO3-TiO2 and CuO-TiO2 systems. The composite nanopowders have novel morphology, and may offer novel electronic, optical, or catalytic properties.

Online processing of tone and intonation in Mandarin: Evidence from ERPs.

PubMed

Liu, Min; Chen, Yiya; Schiller, Niels O

2016-10-01

Event-related potentials (ERPs) were used to investigate the online processing of tone and intonation in Mandarin at the attentive stage. We examined the behavioral and electrophysiological responses of native Mandarin listeners to Mandarin sentences, which contrast in final tones (rising Tone2 or falling Tone4) and intonations (Question or Statement). A clear P300 effect was observed for question-statement contrast in sentences ending with Tone4, but no ERP effect was found for question-statement contrast in sentences ending with Tone2. Our results provide ERP evidence for the interaction of tone and intonation in Mandarin, confirming the findings with behavioral metalinguistic data that native Mandarin listeners can distinguish between question intonation and statement intonation when the intonation is associated with a final Tone4, but fail to do so when the intonation is associated with a final Tone2. Our study extended the understanding of online processing of tone and intonation (1) from the pre-attentive stage to the attentive stage and (2) within a larger domain (i.e. multi-word utterances) than a single word utterance. Copyright © 2016 Elsevier Ltd. All rights reserved.

Water reduction in waste-activated sludge by resettling and filtration in batch. Phase (1): pilot-scale experiments to optimize performance.

PubMed

Trapote, Arturo; Jover, Margarita; Cartagena, Pablo; El Kaddouri, Marouane; Prats, Daniel

2014-08-01

This article describes an effective procedure for reducing the water content of excess sludge production from a wastewater treatment plant by increasing its concentration and, as a consequence, minimizing the volume of sludge to be managed. It consists of a pre-dewatering sludge process, which is used as a preliminary step or alternative to the thickening. It is made up of two discontinuous sequential stages: the first is resettling and the second, filtration through a porous medium. The process is strictly physical, without any chemical additives or electromechanical equipment intervening. The experiment was carried out in a pilot-scale system, consisting of a column of sedimentation that incorporates a filter medium. Different sludge heights were tested over the filter to verify the influence ofhydrostatic pressure on the various final concentrations of each stage. The results show that the initial sludge concentration may increase by more than 570% by the end of the process with the final volume of sludge being reduced in similar proportions and hydrostatic pressure having a limited effect on this final concentration. Moreover, the value of the hydrostatic pressure at which critical specific cake resistance is reached is established.

Interactive effects of aging parameters of AA6056

NASA Astrophysics Data System (ADS)

Dehghani, Kamran; Nekahi, Atiye

2012-10-01

The effect of thermomechanical treatment on the aging behavior of AA6056 aluminum alloy was modeled using response surface methodology (RSM). Two models were developed to predict the final yield stress (FYS) and elongation amounts as well as the optimum conditions of aging process. These were done based on the interactive effects of applied thermomechanical parameters. The optimum condition predicted by the model to attain the maximum strength was pre-aging at 80 °C for 15 h, followed by 70% cold work and subsequent final aging at 165 °C for 4 h, which resulted in the FYS of about 480 MPa. As for the elongation, the optimum condition was pre-aging at 80 °C for 15 h, followed by 30% cold work and final-aging at 165 °C for 4 h, which led to 21% elongation. To verify the suggested optimum conditions, the tests were carried out confirming the high accuracy (above 94%) of the RSM technique as well as the developed models. It is shown that the RSM can be used successfully to optimize the aging process, to determine the significance of aging parameters and to model the combination effect of process variables on the aging behavior of AA6056.

Evaluation of fertilizer-drawn forward osmosis for sustainable agriculture and water reuse in arid regions.

PubMed

Chekli, Laura; Kim, Youngjin; Phuntsho, Sherub; Li, Sheng; Ghaffour, Noreddine; Leiknes, TorOve; Shon, Ho Kyong

2017-02-01

The present study focused on the performance of the FDFO process to achieve simultaneous water reuse from wastewater and production of nutrient solution for hydroponic application. Bio-methane potential (BMP) measurements were firstly carried out to determine the effect of osmotic concentration of wastewater achieved in the FDFO process on the anaerobic activity. Results showed that 95% water recovery from the FDFO process is the optimum value for further AnMBR treatment. Nine different fertilizers were then tested based on their FO performance (i.e. water flux, water recovery and reverse salt flux) and final nutrient concentration. From this initial screening, ammonium phosphate monobasic (MAP), ammonium sulfate (SOA) and mono-potassium phosphate were selected for long term experiments to investigate the maximum water recovery achievable. After the experiments, hydraulic membrane cleaning was performed to assess the water flux recovery. SOA showed the highest water recovery rate, up to 76% while KH 2 PO 4 showed the highest water flux recovery, up to 75% and finally MAP showed the lowest final nutrient concentration. However, substantial dilution was still necessary to comply with the standards for fertigation even if the recovery rate was increased. Copyright © 2016 Elsevier Ltd. All rights reserved.

Use of near-infrared spectroscopy and multipoint measurements for quality control of pharmaceutical drug products.

PubMed

Boiret, Mathieu; Chauchard, Fabien

2017-01-01

Near-infrared (NIR) spectroscopy is a non-destructive analytical technique that enables better-understanding and optimization of pharmaceutical processes and final drug products. The use in line is often limited by acquisition speed and sampling area. This work focuses on performing a multipoint measurement at high acquisition speed at the end of the manufacturing process on a conveyor belt system to control both the distribution and the content of active pharmaceutical ingredient within final drug products, i.e., tablets. A specially designed probe with several collection fibers was developed for this study. By measuring spectral and spatial information, it provides physical and chemical knowledge on the final drug product. The NIR probe was installed on a conveyor belt system that enables the analysis of a lot of tablets. The use of these NIR multipoint measurement probes on a conveyor belt system provided an innovative method that has the potential to be used as a new paradigm to ensure the drug product quality at the end of the manufacturing process and as a new analytical method for the real-time release control strategy. Graphical abstract Use of near-infrared spectroscopy and multipoint measurements for quality control of pharmaceutical drug products.

The Dynamics of Narrative Writing in Primary Grade Children: Writing Process Factors Predict Story Quality

ERIC Educational Resources Information Center

von Koss Torkildsen, Janne; Morken, Frøydis; Helland, Wenche A.; Helland, Turid

2016-01-01

In this study of third grade school children, we investigated the association between writing process measures recorded with key stroke logging and the final written product. Moreover, we examined the cognitive predictors of writing process and product measures. Analyses of key strokes showed that while most children spontaneously made local…

An Operationally Responsive Space Architecture for 2025

DTIC Science & Technology

2008-06-22

Organizational Relationships, Asset Loss Mitigation, Availability, Flexibility, and Streamlined Acquisition Processes . These pillars allowed the solutions...were considered. Analysis was further supported by a performance versus cost process which provided a final test of solution feasibility. Relative cost...Availability, Flexibility, and Streamlined Acquisition Processes . These pillars allowed the solutions, material and non-material, to be organized for

How Teachers Teach the Writing Process. Final Report.

ERIC Educational Resources Information Center

Perl, Sondra; And Others

Presented in this report are the results of a three-year case study designed (1) to document what happened in the classrooms of 10 teachers who were trained in a process approach to the teaching of writing, and (2) to provide those teachers with occasions to deepen their understanding of the process approach, by collaborating with them in the…

75 FR 43329 - Interim Final Rules for Group Health Plans and Health Insurance Issuers Relating to Internal...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-23

... circumstances and, in such cases, the State process must provide notice of the decision as expeditiously as... by the Secretary of Labor. Similarly, with respect to internal claims and appeals processes for... incorporate additional consumer protections so that the State process will continue to apply after the end of...

45 CFR 1336.66 - Procedures and criteria for administration of the Revolving Loan Fund: Responsibilities of the...

Code of Federal Regulations, 2010 CFR

2010-10-01

... package. (d) Loan decision-making process. Decision-making on a loan application includes the recommendations of the staff, the review by the loan review committee and the decision by the Board. (e) Loan closing process. The guidelines for the loan closing process include the finalization of loan terms...

Subject Relative Clauses Are Not Universally Easier to Process: Evidence from Basque

ERIC Educational Resources Information Center

Carreiras, Manuel; Dunabeitia, Jon Andoni; Vergara, Marta; de la Cruz-Pavia, Irene; Laka, Itziar

2010-01-01

Studies from many languages consistently report that subject relative clauses (SR) are easier to process than object relatives (OR). However, Hsiao and Gibson (2003) report an OR preference for Chinese, a finding that has been contested. Here we report faster OR versus SR processing in Basque, an ergative, head-final language with pre-nominal…

40 CFR 60.590 - Applicability and designation of affected facility.

Code of Federal Regulations, 2010 CFR

2010-07-01

... or replacement of equipment (defined in § 60.591) for the purpose of process improvement which is... in § 60.591) within a process unit is an affected facility. (b) Any affected facility under paragraph... “process unit” in § 60.590 of this subpart until the EPA takes final action to require compliance and...

Indirect Fabrication of Lattice Metals with Thin Sections Using Centrifugal Casting

PubMed Central

Mun, Jiwon; Ju, Jaehyung; Thurman, James

2016-01-01

One of the typical methods to manufacture 3D lattice metals is the direct-metal additive manufacturing (AM) process such as Selective Laser Melting (SLM) and Electron Beam Melting (EBM). In spite of its potential processing capability, the direct AM method has several disadvantages such as high cost, poor surface finish of final products, limitation in material selection, high thermal stress, and anisotropic properties of parts. We propose a cost-effective method to manufacture 3D lattice metals. The objective of this study is to provide a detailed protocol on fabrication of 3D lattice metals having a complex shape and a thin wall thickness; e.g., octet truss made of Al and Cu alloys having a unit cell length of 5 mm and a cell wall thickness of 0.5 mm. An overall experimental procedure is divided into eight sections: (a) 3D printing of sacrificial patterns (b) melt-out of support materials (c) removal of residue of support materials (d) pattern assembly (e) investment (f) burn-out of sacrificial patterns (g) centrifugal casting (h) post-processing for final products. The suggested indirect AM technique provides the potential to manufacture ultra-lightweight lattice metals; e.g., lattice structures with Al alloys. It appears that the process parameters should be properly controlled depending on materials and lattice geometry, observing the final products of octet truss metals by the indirect AM technique. PMID:27214495

Parameter optimization and stretch enhancement of AISI 316 sheet using rapid prototyping technique

NASA Astrophysics Data System (ADS)

Moayedfar, M.; Rani, A. M.; Hanaei, H.; Ahmad, A.; Tale, A.

2017-10-01

Incremental sheet forming is a flexible manufacturing process which uses the indenter point-to-point force to shape the sheet metal workpiece into manufactured parts in batch production series. However, the problem sometimes arising from this process is the low plastic point in the stress-strain diagram of the material which leads the low stretching amount before ultra-tensile strain point. Hence, a set of experiments is designed to find the optimum forming parameters in this process for optimum sheet thickness distribution while both sides of the sheet are considered for the surface quality improvement. A five-axis high-speed CNC milling machine is employed to deliver the proper motion based on the programming system while the clamping system for holding the sheet metal was a blank mould. Finally, an electron microscope and roughness machine are utilized to evaluate the surface structure of final parts, illustrate any defect may cause during the forming process and examine the roughness of the final part surface accordingly. The best interaction between parameters is obtained with the optimum values which lead the maximum sheet thickness distribution of 4.211e-01 logarithmic elongation when the depth was 24mm with respect to the design. This study demonstrates that this rapid forming method offers an alternative solution for surface quality improvement of 65% avoiding the low probability of cracks and low probability of crystal structure changes.

Indirect Fabrication of Lattice Metals with Thin Sections Using Centrifugal Casting.

PubMed

Mun, Jiwon; Ju, Jaehyung; Thurman, James

2016-05-14

One of the typical methods to manufacture 3D lattice metals is the direct-metal additive manufacturing (AM) process such as Selective Laser Melting (SLM) and Electron Beam Melting (EBM). In spite of its potential processing capability, the direct AM method has several disadvantages such as high cost, poor surface finish of final products, limitation in material selection, high thermal stress, and anisotropic properties of parts. We propose a cost-effective method to manufacture 3D lattice metals. The objective of this study is to provide a detailed protocol on fabrication of 3D lattice metals having a complex shape and a thin wall thickness; e.g., octet truss made of Al and Cu alloys having a unit cell length of 5 mm and a cell wall thickness of 0.5 mm. An overall experimental procedure is divided into eight sections: (a) 3D printing of sacrificial patterns (b) melt-out of support materials (c) removal of residue of support materials (d) pattern assembly (e) investment (f) burn-out of sacrificial patterns (g) centrifugal casting (h) post-processing for final products. The suggested indirect AM technique provides the potential to manufacture ultra-lightweight lattice metals; e.g., lattice structures with Al alloys. It appears that the process parameters should be properly controlled depending on materials and lattice geometry, observing the final products of octet truss metals by the indirect AM technique.

Improved Detection Technique for Solvent Rinse Cleanliness Verification

NASA Technical Reports Server (NTRS)

Hornung, S. D.; Beeson, H. D.

2001-01-01

The NASA White Sands Test Facility (WSTF) has an ongoing effort to reduce or eliminate usage of cleaning solvents such as CFC-113 and its replacements. These solvents are used in the final clean and cleanliness verification processes for flight and ground support hardware, especially for oxygen systems where organic contaminants can pose an ignition hazard. For the final cleanliness verification in the standard process, the equivalent of one square foot of surface area of parts is rinsed with the solvent, and the final 100 mL of the rinse is captured. The amount of nonvolatile residue (NVR) in the solvent is determined by weight after the evaporation of the solvent. An improved process of sampling this rinse, developed at WSTF, requires evaporation of less than 2 mL of the solvent to make the cleanliness verification. Small amounts of the solvent are evaporated in a clean stainless steel cup, and the cleanliness of the stainless steel cup is measured using a commercially available surface quality monitor. The effectiveness of this new cleanliness verification technique was compared to the accepted NVR sampling procedures. Testing with known contaminants in solution, such as hydraulic fluid, fluorinated lubricants, and cutting and lubricating oils, was performed to establish a correlation between amount in solution and the process response. This report presents the approach and results and discusses the issues in establishing the surface quality monitor-based cleanliness verification.

Quality data collection and management technology of aerospace complex product assembly process

NASA Astrophysics Data System (ADS)

Weng, Gang; Liu, Jianhua; He, Yongxi; Zhuang, Cunbo

2017-04-01

Aiming at solving problems of difficult management and poor traceability for discrete assembly process quality data, a data collection and management method is proposed which take the assembly process and BOM as the core. Data collection method base on workflow technology, data model base on BOM and quality traceability of assembly process is included in the method. Finally, assembly process quality data management system is developed and effective control and management of quality information for complex product assembly process is realized.

State of the art in pathology business process analysis, modeling, design and optimization.

PubMed

Schrader, Thomas; Blobel, Bernd; García-Rojo, Marcial; Daniel, Christel; Słodkowska, Janina

2012-01-01

For analyzing current workflows and processes, for improving them, for quality management and quality assurance, for integrating hardware and software components, but also for education, training and communication between different domains' experts, modeling business process in a pathology department is inevitable. The authors highlight three main processes in pathology: general diagnostic, cytology diagnostic, and autopsy. In this chapter, those processes are formally modeled and described in detail. Finally, specialized processes such as immunohistochemistry and frozen section have been considered.

Overview of Computer Security Certification and Accreditation. Final Report.

ERIC Educational Resources Information Center

Ruthberg, Zella G.; Neugent, William

Primarily intended to familiarize ADP (automatic data processing) policy and information resource managers with the approach to computer security certification and accreditation found in "Guideline to Computer Security Certification and Accreditation," Federal Information Processing Standards Publications (FIPS-PUB) 102, this overview…

Fact Sheet - Final Air Toxics Rule for Steel Pickling and HCI Process Facilities and Hydrochloric Acid Regeneration Plants

EPA Pesticide Factsheets

Fact Sheet summarizing the main points of the national emssions standard for hazaradous air pollutants (NESHAP) for Steel Pickling— HCl Process Facilities and Hydrochloric Acid Regeneration Plants as promulgated on June 22, 1999.

Development of a process for quantifying the benefits of research : final report.

DOT National Transportation Integrated Search

2017-07-04

MnDOT Research Services funds and administers approximately 180 transportation research projects annually at a cost of slightly more than $3 million. This project developed an easy-to-apply process for quantifying the potential benefits of research a...

CHARACTERIZATION OF RISKS POSED BY COMBUSTOR EMISSIONS

EPA Science Inventory

Risk characterization is the final step of the risk assessment process as practiced in the U.S. EPA. In risk characterization, the major scientific evidence and "bottom-line" results from the other components of the risk assessment process, hazard identification, dose-response as...

Putting ultrasound to use in food processing

USDA-ARS?s Scientific Manuscript database

Ultrasound has been applied to a wide range of food processing operations, both in research laboratories and commercially. This emerging technology has received a good deal of interest due to its green nature and nonthermal benefits, which include increased throughput, reduced cost, improved final ...

A Process Evaluation of Project Developmental Continuity: Final Report of the PDC Feasibility Study, 1974-1977.

ERIC Educational Resources Information Center

Love, John M.; And Others

This is the final report of the 3-year feasibility phase of a projected 7-year longitudinal evaluation of Project Developmental Continuity (PDC), a Head Start demonstration program aimed at providing educational and developmental continuity between children's Head Start and primary school experiences. Chapter I gives an overview of the PDC program…

A Comparative Analysis of Transitions from Education to Work in Europe (CATEWE). Final Report [and] Annex to the Final Report.

ERIC Educational Resources Information Center

Smyth, Emer; Gangl, Markus; Raffe, David; Hannan, Damian F.; McCoy, Selina

This project aimed to develop a more comprehensive conceptual framework of school-to-work transitions in different national contexts and apply this framework to the empirical analysis of transition processes across European countries. It drew on these two data sources: European Community Labor Force Survey and integrated databases on national…

Micro Autonomous Systems Research: Systems Engineering Processes for Micro Autonomous Systems

DTIC Science & Technology

2016-11-01

product family design and reconfigurable system design with recent developments in the fields of automated manufacturing and micro-autonomous...mapped to design parameters. These mappings are the mechanism by which physical product designs are formulated. Finally, manufacture of the product ... design tools and manufacturing and testing the resulting design . The final products were inspected and flight tested so that their

Project Head Start Research and Evaluation Center, Syracuse University Research Institute. Final Report, November 1, 1967.

ERIC Educational Resources Information Center

Hall, Vernon; And Others

This document describes the research activities of the Syracuse University Evaluation and Research Center for the year September 1, 1966 through August 31, 1967. This final report is organized on the basis of six research projects, which have been abstracted under the following titles and numbers: (1) Experiments in Grammatical Processing in…

76 FR 14777 - National Dairy Promotion and Research Program; Final Rule on Amendments to the Order

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-18

... Ratios for the Dairy Program was 5.49 (nonfat solids basis) and 7.07 (milk fat basis) from 1998 through... produced and marketed commercially, and the disposition or final usage of the raw milk is not a fact in..., milk powders, dairy fat spreads, whey cheeses, processed cheeses, and numerous varieties of natural...

78 FR 71903 - 2013 Revisions to the Greenhouse Gas Reporting Rule and Final Confidentiality Determinations for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-29

... companies, sinter plants, blast furnaces, basic oxygen process furnace shops. Lead Production 331419 Primary... Act (APA), 5 U.S.C. Chapter 5, generally provides that rules may not take effect earlier than 30 days... adjust their behavior and prepare before the final rule takes effect. To employ the 5 U.S.C. 553(d)(3...

78 FR 9111 - Commercial and Industrial Solid Waste Incineration Units: Reconsideration and Final Amendments...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-07

... established standards in this final rule for the following four subcategories of CISWI units: Incinerators (i... incinerators; ERUs (i.e., units that would be boilers or process heaters if they did not combust solid waste); and waste burning kilns (i.e., units that would be cement kilns if they did not combust solid waste...

Teaching and Learning for the Future. Committee on Multimedia in Teacher Training, Final Report.

ERIC Educational Resources Information Center

Plomp, Tjeerd, Ed.; And Others

This is the final report of the Committee on MultiMedia in Teacher Training (COMMITT), which offers a strategic framework to support efforts of teacher training institutes in the Netherlands to develop their own plans for enhancing the teaching and learning process as well as its outcomes through the application of Information and Communication…

Influences on Academic Achievement Across High and Low Income Countries: A Re-Analysis of IEA Data.

ERIC Educational Resources Information Center

Heyneman, S.; Loxley, W.

Previous international studies of science achievement put the data through a process of winnowing to decide which variables to keep in the final regressions. Variables were allowed to enter the final regressions if they met a minimum beta coefficient criterion of 0.05 averaged across rich and poor countries alike. The criterion was an average…

Research in Information Processing and Computer Science. Final Technical Report.

ERIC Educational Resources Information Center

Carnegie-Mellon Univ., Pittsburgh, PA. Social Studies Curriculum Center.

This is the final scientific research report for the research in programing at Carnegie-Mellon University during 1968-1970. Three team programing efforts during the past two years have been the development of (1) BLISS--a system building language on the PDP-10 computer, (2) LC2--a conversational system on the IBM/360, and L*--a system building…

Head Start Evaluation and Research Center, University of Kansas. Final Report on Research Activities.

ERIC Educational Resources Information Center

Etzel, Barbara C.; And Others

This document is the final report to the Institute of Educational Development for Head Start Research Evaluation activities at the University of Kansas for 1966-67. It contains 16 separate reports of studies completed or in the process of completion. The subject matter of the reports contains 15 distinct topics and warrants individual abstracts.…

An Investigation of Spoken Brazilian Portuguese: Part I, Technical Report. Final Report.

ERIC Educational Resources Information Center

Hutchins, John A.

This final report of a study which developed a working corpus of spoken and written Portuguese from which syntactical studies could be conducted includes computer-processed data on which the findings and analysis are based. A data base, obtained by taping some 487 conversations between Brazil and the United States, serves as the corpus from which…

Rheological of chocolate-flavored, reduced-calories coating as a function of conching process.

PubMed

Medina-Torres, Luis; Sanchez-Olivares, Guadalupe; Nuñez-Ramirez, Diola Marina; Moreno, Leonardo; Calderas, Fausto

2014-07-01

Continuous flow and linear viscoelasticity rheology of chocolate coating is studied in this work using fat substitute gums (xanthan, GX). An alternative conching process, using a Rotor-Estator (RE) type impeller, is proposed. The objective is to obtain a chocolate coating material with improved flow properties. Characterization of the final material through particle size distribution (PSD), differential scanning calorimetry (DSC) and proximal analysis is reported. Particle size distribution of the final material showed less polydispersity and therefore, greater homogeneity; fusion points were also generated at around 20 °C assuming crystal type I (β'2) and II (α). Moreover, the final material exhibited crossover points (higher structure material), whereas the commercial brand chocolate used for comparison did not. The best conditions to produce the coating were maturing of 36 h and 35 °C, showing crossover points around 76 Pa and a 0.505 solids particle dispersion (average particle diameter of 0.364 μm), and a fusion point at 20.04 °C with a ΔHf of 1.40 (J/g). The results indicate that xanthan gum is a good substitute for cocoa butter and provides stability to the final product.

Automatic initial and final segmentation in cleft palate speech of Mandarin speakers

PubMed Central

Liu, Yin; Yin, Heng; Zhang, Junpeng; Zhang, Jing; Zhang, Jiang

2017-01-01

The speech unit segmentation is an important pre-processing step in the analysis of cleft palate speech. In Mandarin, one syllable is composed of two parts: initial and final. In cleft palate speech, the resonance disorders occur at the finals and the voiced initials, while the articulation disorders occur at the unvoiced initials. Thus, the initials and finals are the minimum speech units, which could reflect the characteristics of cleft palate speech disorders. In this work, an automatic initial/final segmentation method is proposed. It is an important preprocessing step in cleft palate speech signal processing. The tested cleft palate speech utterances are collected from the Cleft Palate Speech Treatment Center in the Hospital of Stomatology, Sichuan University, which has the largest cleft palate patients in China. The cleft palate speech data includes 824 speech segments, and the control samples contain 228 speech segments. The syllables are extracted from the speech utterances firstly. The proposed syllable extraction method avoids the training stage, and achieves a good performance for both voiced and unvoiced speech. Then, the syllables are classified into with “quasi-unvoiced” or with “quasi-voiced” initials. Respective initial/final segmentation methods are proposed to these two types of syllables. Moreover, a two-step segmentation method is proposed. The rough locations of syllable and initial/final boundaries are refined in the second segmentation step, in order to improve the robustness of segmentation accuracy. The experiments show that the initial/final segmentation accuracies for syllables with quasi-unvoiced initials are higher than quasi-voiced initials. For the cleft palate speech, the mean time error is 4.4ms for syllables with quasi-unvoiced initials, and 25.7ms for syllables with quasi-voiced initials, and the correct segmentation accuracy P30 for all the syllables is 91.69%. For the control samples, P30 for all the syllables is 91.24%. PMID:28926572

Automatic initial and final segmentation in cleft palate speech of Mandarin speakers.

PubMed

He, Ling; Liu, Yin; Yin, Heng; Zhang, Junpeng; Zhang, Jing; Zhang, Jiang

2017-01-01

The speech unit segmentation is an important pre-processing step in the analysis of cleft palate speech. In Mandarin, one syllable is composed of two parts: initial and final. In cleft palate speech, the resonance disorders occur at the finals and the voiced initials, while the articulation disorders occur at the unvoiced initials. Thus, the initials and finals are the minimum speech units, which could reflect the characteristics of cleft palate speech disorders. In this work, an automatic initial/final segmentation method is proposed. It is an important preprocessing step in cleft palate speech signal processing. The tested cleft palate speech utterances are collected from the Cleft Palate Speech Treatment Center in the Hospital of Stomatology, Sichuan University, which has the largest cleft palate patients in China. The cleft palate speech data includes 824 speech segments, and the control samples contain 228 speech segments. The syllables are extracted from the speech utterances firstly. The proposed syllable extraction method avoids the training stage, and achieves a good performance for both voiced and unvoiced speech. Then, the syllables are classified into with "quasi-unvoiced" or with "quasi-voiced" initials. Respective initial/final segmentation methods are proposed to these two types of syllables. Moreover, a two-step segmentation method is proposed. The rough locations of syllable and initial/final boundaries are refined in the second segmentation step, in order to improve the robustness of segmentation accuracy. The experiments show that the initial/final segmentation accuracies for syllables with quasi-unvoiced initials are higher than quasi-voiced initials. For the cleft palate speech, the mean time error is 4.4ms for syllables with quasi-unvoiced initials, and 25.7ms for syllables with quasi-voiced initials, and the correct segmentation accuracy P30 for all the syllables is 91.69%. For the control samples, P30 for all the syllables is 91.24%.

A Unique Autothermal Thermophilic Aerobic Digestion Process Showing a Dynamic Transition of Physicochemical and Bacterial Characteristics from the Mesophilic to the Thermophilic Phase.

PubMed

Tashiro, Yukihiro; Kanda, Kosuke; Asakura, Yuya; Kii, Toshihiko; Cheng, Huijun; Poudel, Pramod; Okugawa, Yuki; Tashiro, Kosuke; Sakai, Kenji

2018-03-15

A unique autothermal thermophilic aerobic digestion (ATAD) process has been used to convert human excreta to liquid fertilizer in Japan. This study investigated the changes in physicochemical and bacterial community characteristics during the full-scale ATAD process operated for approximately 3 weeks in 2 different years. After initiating simultaneous aeration and mixing using an air-inducing circulator (aerator), the temperature autothermally increased rapidly in the first 1 to 2 days with exhaustive oxygen consumption, leading to a drastic decrease and gradual increase in oxidation-reduction potential in the first 2 days, reached >50°C in the middle 4 to 6 days, and remained steady in the final phase. Volatile fatty acids were rapidly consumed and diminished in the first 2 days, whereas the ammonia nitrogen concentration was relatively stable during the process, despite a gradual pH increase to 9.3. Principal-coordinate analysis of 16S rRNA gene amplicons using next-generation sequencing divided the bacterial community structures into distinct clusters corresponding to three phases, and they were similar in the final phase in both years despite different transitions in the middle phase. The predominant phyla (closest species, dominancy) in the initial, middle, and final phases were Proteobacteria ( Arcobacter trophiarum , 19 to 43%; Acinetobacter towneri , 6.3 to 30%), Bacteroidetes ( Moheibacter sediminis , 43 to 54%), and Firmicutes ( Thermaerobacter composti , 11 to 28%; Heliorestis baculata , 2.1 to 16%), respectively. Two predominant operational taxonomic units (OTUs) in the final phase showed very low similarities to the closest species, indicating that the process is unique compared with previously published ones. This unique process with three distinctive phases would be caused by the aerator with complete aeration. IMPORTANCE Although the autothermal thermophilic aerobic digestion (ATAD) process has several advantages, such as a high degradation capacity, a short treatment period, and inactivation of pathogens, one of the factors limiting its broad application is the high electric power consumption for aerators with a full-scale bioreactor. We elucidated the dynamics of the bacterial community structures, as well as the physicochemical characteristics, in the ATAD process with a full-scale bioreactor from human excreta for 3 weeks. Our results indicated that this unique process can be divided into three distinguishable phases by an aerator with complete aeration and showed a possibility of shortening the digestion period to approximately 10 days. This research not only helps to identify which bacteria play significant roles and how the process can be improved and controlled but also demonstrates an efficient ATAD process with less electric power consumption for worldwide application. Copyright © 2018 American Society for Microbiology.

KSC-2009-2233

NASA Image and Video Library

2009-03-20

CAPE CANAVERAL, Fla. –The NASA Railroad is hauling one of the cars with an Ares I-X segment to the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida. The four reusable motor segments and the nozzle exit cone, manufactured by the Ares I first-stage prime contractor Alliant Techsystems Inc., or ATK, departed Utah March 12 on the seven-day, cross-country trip to Florida. The segments will be delivered to Kennedy's Rotation, Processing and Surge Facility for final processing and integration. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming test flight this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jack Pfaller

KSC-2009-2232

NASA Image and Video Library

2009-03-20

CAPE CANAVERAL, Fla. –This NASA Railroad engine is hauling one of the cars with an Ares I-X segment to the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida. The four reusable motor segments and the nozzle exit cone, manufactured by the Ares I first-stage prime contractor Alliant Techsystems Inc., or ATK, departed Utah March 12 on the seven-day, cross-country trip to Florida. The segments will be delivered to Kennedy's Rotation, Processing and Surge Facility for final processing and integration. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming test flight this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jack Pfaller

An introduction to PYTHIA 8.2

DOE PAGES

Sjöstrand, Torbjörn; Ask, Stefan; Christiansen, Jesper R.; ...

2015-02-11

The Pythia program is a standard tool for the generation of events in high-energy collisions, comprising a coherent set of physics models for the evolution from a few-body hard process to a complex multiparticle final state. It contains a library of hard processes, models for initial- and final-state parton showers, matching and merging methods between hard processes and parton showers, multiparton interactions, beam remnants, string fragmentation and particle decays. It also has a set of utilities and several interfaces to external programs. Pythia 8.2 is the second main release after the complete rewrite from Fortran to C++, and now hasmore » reached such a maturity that it offers a complete replacement for most applications, notably for LHC physics studies. Lastly, the many new features should allow an improved description of data.« less

Superresolution with the focused plenoptic camera

NASA Astrophysics Data System (ADS)

Georgiev, Todor; Chunev, Georgi; Lumsdaine, Andrew

2011-03-01

Digital images from a CCD or CMOS sensor with a color filter array must undergo a demosaicing process to combine the separate color samples into a single color image. This interpolation process can interfere with the subsequent superresolution process. Plenoptic superresolution, which relies on precise sub-pixel sampling across captured microimages, is particularly sensitive to such resampling of the raw data. In this paper we present an approach for superresolving plenoptic images that takes place at the time of demosaicing the raw color image data. Our approach exploits the interleaving provided by typical color filter arrays (e.g., Bayer filter) to further refine plenoptic sub-pixel sampling. Our rendering algorithm treats the color channels in a plenoptic image separately, which improves final superresolution by a factor of two. With appropriate plenoptic capture we show the theoretical possibility for rendering final images at full sensor resolution.

Evidence of coherent $$K^{+}$$ meson production in neutrino-nucleus scattering

DOE PAGES

Wang, Z.

2016-08-05

Neutrino-induced charged-current coherent kaon production ν μA→μ -K +A is a rare, inelastic electroweak process that brings a K + on shell and leaves the target nucleus intact in its ground state. This process is significantly lower in rate than the neutrino-induced charged-current coherent pion production because of Cabibbo suppression and a kinematic suppression due to the larger kaon mass. We search for such events in the scintillator tracker of MINERvA by observing the final state K +, μ -, and no other detector activity, and by using the kinematics of the final state particles to reconstruct the small momentummore » transfer to the nucleus, which is a model-independent characteristic of coherent scattering. Furthermore, we find the first experimental evidence for the process at 3σ significance.« less

Annealing of (DU-10Mo)-Zr Co-Rolled Foils

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pacheco, Robin Montoya; Alexander, David John; Mccabe, Rodney James

2017-01-20

Producing uranium-10wt% molybdenum (DU-10Mo) foils to clad with Al first requires initial bonding of the DU-10Mo foil to zirconium (Zr) by hot rolling, followed by cold rolling to final thickness. Rolling often produces wavy (DU-10Mo)-Zr foils that should be flattened before further processing, as any distortions could affect the final alignment and bonding of the Al cladding to the Zr co-rolled surface layer; this bonding is achieved by a hot isostatic pressing (HIP) process. Distortions in the (DU-10Mo)-Zr foil may cause the fuel foil to press against the Al cladding and thus create thinner or thicker areas in the Almore » cladding layer during the HIP cycle. Post machining is difficult and risky at this stage in the process since there is a chance of hitting the DU-10Mo. Therefore, it is very important to establish a process to flatten and remove any waviness. This study was conducted to determine if a simple annealing treatment could flatten wavy foils. Using the same starting material (i.e. DU-10Mo coupons of the same thickness), five different levels of hot rolling and cold rolling, combined with five different annealing treatments, were performed to determine the effect of these processing variables on flatness, bonding of layers, annealing response, microstructure, and hardness. The same final thickness was reached in all cases. Micrographs, textures, and hardness measurements were obtained for the various processing combinations. Based on these results, it was concluded that annealing at 650°C or higher is an effective treatment to appreciably reduce foil waviness.« less

Plutonium Finishing Plant (PFP) Final Safety Analysis Report (FSAR) [SEC 1 THRU 11

DOE Office of Scientific and Technical Information (OSTI.GOV)

ULLAH, M K

2001-02-26

The Plutonium Finishing Plant (PFP) is located on the US Department of Energy (DOE) Hanford Site in south central Washington State. The DOE Richland Operations (DOE-RL) Project Hanford Management Contract (PHMC) is with Fluor Hanford Inc. (FH). Westinghouse Safety Management Systems (WSMS) provides management support to the PFP facility. Since 1991, the mission of the PFP has changed from plutonium material processing to preparation for decontamination and decommissioning (D and D). The PFP is in transition between its previous mission and the proposed D and D mission. The objective of the transition is to place the facility into a stablemore » state for long-term storage of plutonium materials before final disposition of the facility. Accordingly, this update of the Final Safety Analysis Report (FSAR) reflects the current status of the buildings, equipment, and operations during this transition. The primary product of the PFP was plutonium metal in the form of 2.2-kg, cylindrical ingots called buttoms. Plutonium nitrate was one of several chemical compounds containing plutonium that were produced as an intermediate processing product. Plutonium recovery was performed at the Plutonium Reclamation Facility (PRF) and plutonium conversion (from a nitrate form to a metal form) was performed at the Remote Mechanical C (RMC) Line as the primary processes. Plutonium oxide was also produced at the Remote Mechanical A (RMA) Line. Plutonium processed at the PFP contained both weapons-grade and fuels-grade plutonium materials. The capability existed to process both weapons-grade and fuels-grade material through the PRF and only weapons-grade material through the RMC Line although fuels-grade material was processed through the line before 1984. Amounts of these materials exist in storage throughout the facility in various residual forms left from previous years of operations.« less

An electronic safety screening process during inpatient computerized physician order entry improves the efficiency of magnetic resonance imaging exams.

PubMed

Schneider, Erika; Ruggieri, Paul; Fromwiller, Lauren; Underwood, Reginald; Gurland, Brooke; Yurkschatt, Cynthia; Kubiak, Kevin; Obuchowski, Nancy A

2013-12-01

Delays between order and magnetic resonance (MR) exam often result when using the conventional paper-based MR safety screening process. The impact of an electronic MR safety screening process imbedded in a computerized physician order entry (CPOE) system was evaluated. Retrospective chart review of 4 months of inpatient MR exam orders and reports was performed before and after implementation of electronic MR safety documentation. Time from order to MR exam completion, time from MR exam completion to final radiology report, and time from first order to final report were analyzed by exam anatomy. Length of stay (LOS) and date of service within the admission were also analyzed. We evaluated 1947 individual MR orders in 1549 patients under an institutional review board exemption and a waiver of informed consent. Implementation of the electronic safety screening process resulted in a significant decrease of 1.1 hours (95% confidence interval 1.0-1.3 hours) in the mean time between first order to final report and a nonsignificant decrease of 0.8 hour in the median time from first order to exam end. There was a 1-day reduction (P = .697) in the time from admission to the MR exam compared to the paper process. No significant change in LOS was found except in neurological intensive care patients imaged within the first 24 hours of their admission, where a mean 0.9-day decrease was found. Benefits of an electronic process for MR safety screening include enabling inpatients to have decreased time to MR exams, thus enabling earlier diagnosis and treatment and reduced LOS. Copyright © 2013 AUR. Published by Elsevier Inc. All rights reserved.

Social network supported process recommender system.

PubMed

Ye, Yanming; Yin, Jianwei; Xu, Yueshen

2014-01-01

Process recommendation technologies have gained more and more attention in the field of intelligent business process modeling to assist the process modeling. However, most of the existing technologies only use the process structure analysis and do not take the social features of processes into account, while the process modeling is complex and comprehensive in most situations. This paper studies the feasibility of social network research technologies on process recommendation and builds a social network system of processes based on the features similarities. Then, three process matching degree measurements are presented and the system implementation is discussed subsequently. Finally, experimental evaluations and future works are introduced.

NASA Hazard Analysis Process

NASA Technical Reports Server (NTRS)

Deckert, George

2010-01-01

This viewgraph presentation reviews The NASA Hazard Analysis process. The contents include: 1) Significant Incidents and Close Calls in Human Spaceflight; 2) Subsystem Safety Engineering Through the Project Life Cycle; 3) The Risk Informed Design Process; 4) Types of NASA Hazard Analysis; 5) Preliminary Hazard Analysis (PHA); 6) Hazard Analysis Process; 7) Identify Hazardous Conditions; 8) Consider All Interfaces; 9) Work a Preliminary Hazard List; 10) NASA Generic Hazards List; and 11) Final Thoughts

Processing waste fats into a fuel oil substitute

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pudel, F.; Lengenfeld, P.

1993-12-31

Waste fats have a high energy potential. They also contain impurities. For example, fats used for deep-frying contain high contents of solids, water, and chlorides. The process described in this paper removes the impurities by simple processing such as screening, washing, separating, drying, and filtering. The final quality of processed fat allows its use as a fuel oil substitute, and also as a raw material for chemical production.

Final disposition and quality auditing of the rehabilitation process in wild raptors admitted to a Wildlife Rehabilitation Centre in Catalonia, Spain, during a twelve year period (1995-2007).

PubMed

Molina-López, Rafael A; Casal, Jordi; Darwich, Laila

2013-01-01

Variability in reporting and classification methods in previous published data of the final dispositions in the rehabilitation of wild raptors makes use of this data limited in trying to audit the quality of the rehabilitation process. Crude as well as stratified disposition rates are needed if quality auditing of the rehabilitation process is to be adequately performed. Final dispositions of 6221 hospitalized wild raptors admitted at a wildlife rehabilitation centre (WRC) of Catalonia during 1995-2007 were analyzed. These dispositions were calculated as the euthanasia (Er), unassisted mortality (Mr), release (Rr) and captivity rates (Cr)., time to death (Td) for dead and euthanized raptors, and length of stay for released (Tr) raptors was estimated. Stratified analyses by main causes of admission and clinical signs were performed. THE DISPOSITION FOR THE TOTAL POPULATION WERE: Er = 30.6%, Mr = 19.1%, Rr = 47.2%, and Cr = 3%. By main causes of admission, Er was higher in the trauma category (34.2%), whereas Mr was found similar between trauma (37.4%) and non-trauma categories (34.8%). The highest Rr was observed for the orphaned group (77.9%). Furthermore, Cr was low in all the categories (<4%). By clinical signs, the highest Er was found in animals suffering musculoskeletal (37.9%) or skin (32.3%) lesions; Mr was high in infectious/parasitic diseases (66.7%) and in case of neurological symptoms (64.5%). The euthanized birds had a median Td = 1 day (P10 = 0-P90 = 59) for both trauma and non-trauma categories, and Td = 36 days for the orphaned young group (P10 = 0; P90 = 596). The median Td in the unassisted dead birds was 2 days for all the categories (P10 = 0-P90 = 31). Finally, the median Tr in the centre was variable among categories. Reporting of final dispositions in wildlife rehabilitation should include the crude and stratified rates (Er, Mr, Rr, and Cr), by causes and clinical presentation, as well as Td and Tr, to allow meaningful auditing of the rehabilitation process quality.

Degradation of triclosan and its main intermediates during the combined irradiation and biological treatment.

PubMed

Wang, Shizong; Wang, Jianlong

2018-05-01

Triclosan is an extensively applied antimicrobial agent which has been frequently detected in the environment. In this paper, the degradation of triclosan and its main intermediates was investigated during the combined irradiation and biological treatment. The results showed that triclosan degradation increased with increase of absorbed dose, the removal efficiency of triclosan was 62%, 77%, 87%, 91% and 94%, respectively at 1, 2, 3, 4 and 5 kGy. The final removal efficiency of triclosan after the combined irradiation and biological process was 81%, 86%, 90%, 92% and 95%, respectively. During the irradiation process, two main intermediates, that is, 4,4'-2'-phenoxyphenol (Intermediate 1) and 4-chloro-2'-phenoxyphenol (Intermediate 2) were detected, in which Intermediate 1 dominated during the irradiation process. In the following biological treatment process, Intermediates 1 and 2 could be further degraded. In single biological treatment process, the final removal efficiency of triclosan was 54%, and Intermediates 1 and 2 were detected. Intermediate 1 could be biodegraded while Intermediate 2 could not. The concentration of Intermediate 2 increased during biological treatment process. In conclusion, irradiation as pre-treatment process can enhance the degradation of triclosan and improve the biodegradability of Intermediate 2. Combined irradiation and biological process can be promising for treating antibiotic-containing wastewater.

An assessment of space shuttle flight software development processes

NASA Technical Reports Server (NTRS)

1993-01-01

In early 1991, the National Aeronautics and Space Administration's (NASA's) Office of Space Flight commissioned the Aeronautics and Space Engineering Board (ASEB) of the National Research Council (NRC) to investigate the adequacy of the current process by which NASA develops and verifies changes and updates to the Space Shuttle flight software. The Committee for Review of Oversight Mechanisms for Space Shuttle Flight Software Processes was convened in Jan. 1992 to accomplish the following tasks: (1) review the entire flight software development process from the initial requirements definition phase to final implementation, including object code build and final machine loading; (2) review and critique NASA's independent verification and validation process and mechanisms, including NASA's established software development and testing standards; (3) determine the acceptability and adequacy of the complete flight software development process, including the embedded validation and verification processes through comparison with (1) generally accepted industry practices, and (2) generally accepted Department of Defense and/or other government practices (comparing NASA's program with organizations and projects having similar volumes of software development, software maturity, complexity, criticality, lines of code, and national standards); (4) consider whether independent verification and validation should continue. An overview of the study, independent verification and validation of critical software, and the Space Shuttle flight software development process are addressed. Findings and recommendations are presented.

Improving the Simplified Acquisition of Base Engineering Requirements (SABER) Delivery Order Award Process: Results of a Process Improvement Plan

DTIC Science & Technology

1991-09-01

putting all tasks directed towsrds achieving an outcome in aequence. The tasks can be viewed as steps in the process (39:2.3). Using this...improvement opportunity is investigated. A plan is developed, root causes are identified, and solutions are tested and implemented. The process is... solutions , check for actual improvement, and integrate the successful improvements into the process. ?UP 7. Check Improvement Performance. Finally, the

Hot forming and quenching pilot process development for low cost and low environmental impact manufacturing.

NASA Astrophysics Data System (ADS)

Hall, Roger W.; Foster, Alistair; Herrmann Praturlon, Anja

2017-09-01

The Hot Forming and in-tool Quenching (HFQ®) process is a proven technique to enable complex shaped stampings to be manufactured from high strength aluminium. Its widespread uptake for high volume production will be maximised if it is able to wholly amortise the additional investment cost of this process compared to conventional deep drawing techniques. This paper discusses the use of three techniques to guide some of the development decisions taken during upscaling of the HFQ® process. Modelling of Process timing, Cost and Life-cycle impact were found to be effective tools to identify where development budget could be focused in order to be able to manufacture low cost panels of different sizes from many different alloys in a sustainable way. The results confirm that raw material cost, panel trimming, and artificial ageing were some of the highest contributing factors to final component cost. Additionally, heat treatment and lubricant removal stages played a significant role in the overall life-cycle assessment of the final products. These findings confirmed development priorities as novel furnace design, fast artificial ageing and low-cost alloy development.

Comparative study of the bioconversion process using R-(+)- and S-(-)-limonene as substrates for Fusarium oxysporum 152B.

PubMed

Molina, Gustavo; Bution, Murillo L; Bicas, Juliano L; Dolder, Mary Anne Heidi; Pastore, Gláucia M

2015-05-01

This study compared the bioconversion process of S-(-)-limonene into limonene-1,2-diol with the already established biotransformation of R-(+)-limonene into α-terpineol using the same biocatalyst in both processes, Fusarium oxysporum 152B. The bioconversion of the S-(-)-isomer was tested on cell permeabilisation under anaerobic conditions and using a biphasic system. When submitted to permeabilisation trials, this biocatalyst has shown a relatively high resistance; still, no production of limonene-1,2-diol and a loss of activity of the biocatalyst were observed after intense cell treatment, indicating a complete loss of cell viability. Furthermore, the results showed that this process can be characterised as an aerobic system that was catalysed by limonene-1,2-epoxide hydrolase, had an intracellular nature and was cofactor-dependent because the final product was not detected by an anaerobic process. Finally, this is the first report to characterise the bioconversion of R-(+)- and S-(-)-limonene by cellular detoxification using ultra-structural analysis. Copyright © 2014 Elsevier Ltd. All rights reserved.

Food structure: Its formation and relationships with other properties.

PubMed

Joardder, Mohammad U H; Kumar, Chandan; Karim, M A

2017-04-13

Food materials are complex in nature as it has heterogeneous, amorphous, hygroscopic and porous properties. During processing, microstructure of food materials changes which significantly affects other properties of food. An appropriate understanding of the microstructure of the raw food material and its evolution during processing is critical in order to understand and accurately describe dehydration processes and quality anticipation. This review critically assesses the factors that influence the modification of microstructure in the course of drying of fruits and vegetables. The effect of simultaneous heat and mass transfer on microstructure in various drying methods is investigated. Effects of changes in microstructure on other functional properties of dried foods are discussed. After an extensive review of the literature, it is found that development of food structure significantly depends on fresh food properties and process parameters. Also, modification of microstructure influences the other properties of final product. An enhanced understanding of the relationships between food microstructure, drying process parameters and final product quality will facilitate the energy efficient optimum design of the food processor in order to achieve high-quality food.

Advances in Integrated Computational Materials Engineering "ICME"

NASA Astrophysics Data System (ADS)

Hirsch, Jürgen

The methods of Integrated Computational Materials Engineering that were developed and successfully applied for Aluminium have been constantly improved. The main aspects and recent advances of integrated material and process modeling are simulations of material properties like strength and forming properties and for the specific microstructure evolution during processing (rolling, extrusion, annealing) under the influence of material constitution and process variations through the production process down to the final application. Examples are discussed for the through-process simulation of microstructures and related properties of Aluminium sheet, including DC ingot casting, pre-heating and homogenization, hot and cold rolling, final annealing. New results are included of simulation solution annealing and age hardening of 6xxx alloys for automotive applications. Physically based quantitative descriptions and computer assisted evaluation methods are new ICME methods of integrating new simulation tools also for customer applications, like heat affected zones in welding of age hardening alloys. The aspects of estimating the effect of specific elements due to growing recycling volumes requested also for high end Aluminium products are also discussed, being of special interest in the Aluminium producing industries.

Stereoselective Behavior of the Chiral Herbicides Diclofop-Methyl and Diclofop During the Soy Sauce Brewing Process.

PubMed

Lu, Yuele; Zhang, Dong; Liao, Yahui; Diao, Jinling; Chen, Xiaolong

2016-01-01

Chiral pesticides are now receiving more and more attention in the food-making process. This experiment studied the enantioselective behavior of diclofop-methyl (DM) and its main metabolite, diclofop (DC), during the soy sauce brewing process. Two kinds of commonly used strains, Aspergillus oryzae and Saccharomyces rouxii, were investigated. However, they showed a different degradation ability to the enantiomers of DM and DC. It was observed that (-)-(S)-DM was degraded much faster than (+)-(R)-DM by Saccharomyces rouxii, while no stereoselective degradation was found by Aspergillus oryzae. DC represented a relatively long residue period in this fermentation process and both strains showed a weak degradation ability to DC, especially Saccharomyces rouxii. There was little DC detected in the final product, while most of the DC residues persisted in the lees, which were usually used as animal feeds or discarded into the environment directly as waste. Therefore, more attention should be paid to the soy sauce brewing process concerning pesticide residues both in the final product and byproducts. © 2015 Wiley Periodicals, Inc.

Integrated ecotechnology approach towards treatment of complex wastewater with simultaneous bioenergy production.

PubMed

Hemalatha, Manupati; Sravan, J Shanthi; Yeruva, Dileep Kumar; Venkata Mohan, S

2017-10-01

Sequential integration of three stage diverse biological processes was studied by exploiting the individual process advantage towards enhanced treatment of complex chemical based wastewater. A successful attempt to integrate sequence batch reactor (SBR) with bioelectrochemical treatment (BET) and finally with microalgae treatment was studied. The sequential integration has showed individual substrate degradation (COD) of 55% in SBR, 49% in BET and 56% in microalgae, accounting for a consolidated treatment efficiency of 90%. Nitrates removal efficiency of 25% was observed in SBR, 31% in BET and 44% in microalgae, with a total efficiency of 72%. The SBR treated effluents fed to BET with the electrode intervention showed TDS removal. BET exhibited relatively higher process performance than SBR. The integration approach significantly overcame the individual process limitations along with value addition as biomass (1.75g/L), carbohydrates (640mg/g), lipids (15%) and bioelectricity. The study resulted in providing a strategy of combining SBR as pretreatment step to BET process and finally polishing with microalgae cultivation achieving the benefits of enhanced wastewater treatment along with value addition. Copyright © 2017 Elsevier Ltd. All rights reserved.

Comparative study on the conventional and non thermal simultaneous saccharification and fermentation of Manihot glaziovii root starch

NASA Astrophysics Data System (ADS)

Hargono, Kumoro, Andri Cahyo; Jos, Bakti

2015-12-01

Inconventional ethanol production process, starch is converted into dextrins via liquefaction using α-amylase enzyme at high temperature (90-120°C). Then, dextrins are saccharified by glucoamylase to obtain to monomeric sugars (glucose). Recently, a granular starch hydrolyzing enzymes (GSHE), Stargen 002, was developed to convert starch into dextrins at low temperature (< 32°C) and hydrolyzes dextrins into glucose. The subject of this research was to compare ethanol production using a granular starch hydrolyzing enzymes and conventional enzymatic liquefaction and saccharification in cassava starch processing. Starch slurry concentrations were 20% w/v, and dosage of enzymes 0.50, 1.0 and 2%, respectively, were studied. After 48 hr process the final ethanol concentration for the respective enzyme concentration for conventional process were 34.90, 36.16 and 42.10 g/L, whereas for the non-thermal treatment, final ethanol concentration were 46.4, 57.62 and 59.65 g/L, respectively. By implementation of this non thermal process, the use of energy can be saved by carrying out saccharification step at lower temperature (30°C) could be realized.

76 FR 17611 - Propylene Oxide; Proposed Pesticide Tolerance

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-30

...: This document proposes to amend the propylene oxide tolerance on ``nut, tree, group 14'' to ``nutmeat... ``nut, tree, group 14'' to read ``nutmeat, processed, except peanuts.'' A final rule published in the... the propylene oxide tolerance by replacing ``nutmeat, processed, except peanuts'' with ``nut, tree...

78 FR 20625 - Spent Nuclear Fuel Management at the Savannah River Site

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-05

... processing is a chemical separations process that involves dissolving spent fuel in nitric acid and... Engineering Laboratory Environmental Restoration and Waste Management Programs Final Environmental Impact... chemical properties, and radionuclide inventory. The fuel groups and the seven technologies that could be...

36 CFR 9.86 - Application review process and approval standards.

Code of Federal Regulations, 2014 CFR

2014-07-01

... review process and approval standards. (a) The Regional Director will review applications submitted... applicable laws, Executive Orders and regulations, the Regional Director will promptly notify the AMRAP agency coordinator of the anticipated date of a final decision. (b) The Regional Director is responsible...

36 CFR 9.86 - Application review process and approval standards.

Code of Federal Regulations, 2012 CFR

2012-07-01

... review process and approval standards. (a) The Regional Director will review applications submitted... applicable laws, Executive Orders and regulations, the Regional Director will promptly notify the AMRAP agency coordinator of the anticipated date of a final decision. (b) The Regional Director is responsible...

77 FR 53236 - Proposed International Isotopes Fluorine Extraction Process and Depleted Uranium Deconversion...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-31

... NUCLEAR REGULATORY COMMISSION [NRC-2010-0143] Proposed International Isotopes Fluorine Extraction Process and Depleted Uranium Deconversion Plant in Lea County, New Mexico AGENCY: Nuclear Regulatory... U.S. Nuclear Regulatory Commission (NRC or the Commission) has published the Final Environmental...

Wavelet-Based Processing for Fiber Optic Sensing Systems

NASA Technical Reports Server (NTRS)

Hamory, Philip J. (Inventor); Parker, Allen R., Jr. (Inventor)

2016-01-01

The present invention is an improved method of processing conglomerate data. The method employs a Triband Wavelet Transform that decomposes and decimates the conglomerate signal to obtain a final result. The invention may be employed to improve performance of Optical Frequency Domain Reflectometry systems.

Final Air Toxics Standards for Clay Ceramics Manufacturing, Glass Manufacturing, and Secondary Nonferrous Metals Processing Area Sources Fact Sheet

EPA Pesticide Factsheets

This page contains a December 2007 fact sheet with information regarding the National Emissions Standards for Hazardous Air Pollutants (NESHAP) for Clay Ceramics Manufacturing, Glass Manufacturing, and Secondary Nonferrous Metals Processing Area Sources

Achieving Continuous Manufacturing for Final Dosage Formation: Challenges and How to Meet Them May 20-21 2014 Continuous Manufacturing Symposium.

PubMed

Byrn, Stephen; Futran, Maricio; Thomas, Hayden; Jayjock, Eric; Maron, Nicola; Meyer, Robert F; Myerson, Allan S; Thien, Michael P; Trout, Bernhardt L

2015-03-01

We describe the key issues and possibilities for continuous final dosage formation, otherwise known as downstream processing or drug product manufacturing. A distinction is made between heterogeneous processing and homogeneous processing, the latter of which is expected to add more value to continuous manufacturing. We also give the key motivations for moving to continuous manufacturing, some of the exciting new technologies, and the barriers to implementation of continuous manufacturing. Continuous processing of heterogeneous blends is the natural first step in converting existing batch processes to continuous. In heterogeneous processing, there are discrete particles that can segregate, versus in homogeneous processing, components are blended and homogenized such that they do not segregate. Heterogeneous processing can incorporate technologies that are closer to existing technologies, where homogeneous processing necessitates the development and incorporation of new technologies. Homogeneous processing has the greatest potential for reaping the full rewards of continuous manufacturing, but it takes long-term vision and a more significant change in process development than heterogeneous processing. Heterogeneous processing has the detriment that, as the technologies are adopted rather than developed, there is a strong tendency to incorporate correction steps, what we call below "The Rube Goldberg Problem." Thus, although heterogeneous processing will likely play a major role in the near-term transformation of heterogeneous to continuous processing, it is expected that homogeneous processing is the next step that will follow. Specific action items for industry leaders are. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

Sludge thermal oxidation processes: mineral recycling, energy impact, and greenhouse effect gases release.

PubMed

Guibelin, E

2004-01-01

Different treatment routes have been studied for a mixed sludge: the conventional agricultural use is compared with the thermal oxidation processes, including incineration (in gaseous phase) and wet air oxidation (in liquid phase). The interest of a sludge digestion prior to the final treatment has been also considered according to the two major criteria, which are the fossil energy utilisation and the greenhouse effect gases (CO2, CH4, N2O) release. Thermal energy has to be recovered on thermal processes to make these processes environmentally friendly, otherwise their main interest is to extract or destroy micropollutants and pathogens from the carbon cycle. In case of continuous energy recovery, incineration can produce more energy than it consumes. Digestion is especially interesting for agriculture: according to these two schemes, the energy final balance can also be in excess. As to wet air oxidation, it is probably one of the best ways to minimize greenhouse effect gases emission.

The Theory of High Energy Collision Processes - Final Report DOE/ER/40158-1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wu, Tai, T.

In 1984, DOE awarded Harvard University a new Grant DE-FG02-84ER40158 to continue their support of Tai Tsun Wu as Principal Investigator of research on the theory of high energy collision processes. This Grant was renewed and remained active continuously from June 1, 1984 through November 30, 2007. Topics of interest during the 23-year duration of this Grant include: the theory and phenomenology of collision and production processes at ever higher energies; helicity methods of QED and QCD; neutrino oscillations and masses; Yang-Mills gauge theory; Beamstrahlung; Fermi pseudopotentials; magnetic monopoles and dyons; cosmology; classical confinement; mass relations; Bose-Einstein condensation; and large-momentum-transfermore » scattering processes. This Final Report describes the research carried out on Grant DE-FG02-84ER40158 for the period June 1, 1984 through November 30, 2007. Two books resulted from this project and a total of 125 publications.« less

Flank wear analysing of high speed end milling for hardened steel D2 using Taguchi Method

NASA Astrophysics Data System (ADS)

Hazza Faizi Al-Hazza, Muataz; Ibrahim, Nur Asmawiyah bt; Adesta, Erry T. Y.; Khan, Ahsan Ali; Abdullah Sidek, Atiah Bt.

2017-03-01

One of the main challenges for any manufacturer is how to decrease the machining cost without affecting the final quality of the product. One of the new advanced machining processes in industry is the high speed hard end milling process that merges three advanced machining processes: high speed milling, hard milling and dry milling. However, one of the most important challenges in this process is to control the flank wear rate. Therefore a analyzing the flank wear rate during machining should be investigated in order to determine the best cutting levels that will not affect the final quality of the product. In this research Taguchi method has been used to investigate the effect of cutting speed, feed rate and depth of cut and determine the best level s to minimize the flank wear rate up to total length of 0.3mm based on the ISO standard to maintain the finishing requirements.

A new polishing process for large-aperture and high-precision aspheric surface

NASA Astrophysics Data System (ADS)

Nie, Xuqing; Li, Shengyi; Dai, Yifan; Song, Ci

2013-07-01

The high-precision aspheric surface is hard to be achieved due to the mid-spatial frequency error in the finishing step. The influence of mid-spatial frequency error is studied through the simulations and experiments. In this paper, a new polishing process based on magnetorheological finishing (MRF), smooth polishing (SP) and ion beam figuring (IBF) is proposed. A 400mm aperture parabolic surface is polished with this new process. The smooth polishing (SP) is applied after rough machining to control the MSF error. In the middle finishing step, most of low-spatial frequency error is removed by MRF rapidly, then the mid-spatial frequency error is restricted by SP, finally ion beam figuring is used to finish the surface. The surface accuracy is improved from the initial 37.691nm (rms, 95% aperture) to the final 4.195nm. The results show that the new polishing process is effective to manufacture large-aperture and high-precision aspheric surface.

Treatments To Produce Stabilized Aluminum Mirrors for Cryogenic Uses

NASA Technical Reports Server (NTRS)

Zewari, Wahid; Barthelmy, Michael; Ohl, Raymond

2005-01-01

Five metallurgical treatments have been tested as means of stabilizing mirrors that are made of aluminum alloy 6061 and are intended for use in cryogenic applications. Aluminum alloy 6061 is favored as a mirror material by many scientists and engineers. Like other alloys, it shrinks upon cool-down from room temperature to cryogenic temperature. This shrinkage degrades the optical quality of the mirror surfaces. Hence, the metallurgical treatments were tested to determine which one could be most effective in minimizing the adverse optical effects of cooldown to cryogenic temperatures. Each of the five metallurgical treatments comprises a multistep process, the steps of which are interspersed with the steps of the mirror-fabrication process. The five metallurgical-treatment/fabrication.- process combinations were compared with each other and with a benchmark fabrication process, in which a mirror is made from an alloy blank by (1) symmetrical rough machining, (2) finish machining to within 0.006 in. (. 0.15 mm) of final dimensions, and finally (3) diamond turning to a mirror finish.

When locomotion is used to interact with the environment: investigation of the link between emotions and the twofold goal-directed locomotion in humans.

PubMed

Vernazza-Martin, S; Longuet, S; Damry, T; Chamot, J M; Dru, V

2015-10-01

Walking as a means to interact with the environment has a twofold goal: body displacement (intermediate goal) and the future action on the environment (final representational goal). This involves different processes that plan, program, and control goal-directed locomotion linked to motivation as an "emotional state," which leads to achieving this twofold goal. The aim of the present study was to determine whether emotional valence associated with the final representational goal influences these processes or whether they depend more on the emotional valence associated with the intermediate goal in young adults. Twenty subjects, aged 18-35 years, were instructed to erase an emotional picture that appeared on a wall as soon as they saw it. They had to press a stop button located 5 m in front of them with their right hand. Their gait was analyzed using a force platform and the Vicon system. The main results suggest that the emotional valence of the intermediate goal has the greatest effect on the processes that organize and modulate goal-directed locomotion. A positive valence facilitates cognitive processes involved in the temporal organization of locomotion. A negative valence disturbs the cognitive processes involved in the spatial organization of the locomotion and online motor control, leading to a deviating trajectory and a final body position that is more distant from the stop button. These results are discussed in line with the motivational direction hypothesis and with the affective meaning of the intended response goal.

Coal technology program progress report, February 1976

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

Final testing of the 20-atm bench-scale system is underway in preparation for experiments with hydrogen. Laboratory-scale testing of a number of inexpensive pure compounds to improve the settling rate of solids in Solvent Refined Coal (SRC) unfiltered oil (UFO), bench-scale testing of the effect of the Tretolite additive on settling, and characterization tests on a new sample of UFO from the PAMCO-SRC process are reported. Experimental engineering support of an in situ gasification process include low-temperature pyrolyses at exceptionally low heating rates (0.3/sup 0/C/min). Highly pyrophoric chars were consistently produced. Aqueous by-products from coal conversion technologies and oil shale retortingmore » have been analyzed directly to determine major organic components. A report is being prepared discussing various aspects of the engineering evaluations of nuclear process heat for coal. A bench-scale test program on thermochemical water splitting for hydrogen production is under consideration. In the coal-fueled MIUS program, preparations for procurement of tubing for the matrix in the fluidized-bed furnace and for fabrication of the furnace continued. Analyses of the AiResearch gas turbine and recuperator under coal-fueled MIUS operating conditions are near completion. Process flow diagrams and heat and material balances were completed for most of the units in the synthoil process. Overall utilities requirements were calculated and the coal preparation flowsheets were finalized. For hydrocarbonization, the flowsheet was revised to include additional coal data. Flowsheets were finalized for the acid gas separation and recycle, and the oil-solids separation. (LTN)« less

Future Aeronautical Communication Infrastructure Technology Investigation

NASA Technical Reports Server (NTRS)

Gilbert, Tricia; Jin, Jenny; Bergerm Jason; Henriksen, Steven

2008-01-01

This National Aeronautics and Space Administration (NASA) Contractor Report summarizes and documents the work performed to investigate technologies that could support long-term aeronautical mobile communications operating concepts for air traffic management (ATM) in the timeframe of 2020 and beyond, and includes the associated findings and recommendations made by ITT Corporation and NASA Glenn Research Center to the Federal Aviation Administration (FAA). The work was completed as the final phase of a multiyear NASA contract in support of the Future Communication Study (FCS), a cooperative research and development program of the United States FAA, NASA, and EUROCONTROL. This final report focuses on an assessment of final five candidate technologies, and also provides an overview of the entire technology assessment process, including final recommendations.

Development of manufacturing methods for the production of superconductive devices. Final technical documentary report, 28 Jun 1965--27 Jun 1969. [Plasma arc process

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haid, D.A.; Fietz, W.A.

1969-06-01

The effort to scale-up the plasma-arc process to produce large solenoids and saddle coils is described. Large coils (up to 16-/sup 3///sub 4/ in. and 41-in. length) of three different configurations, helical, ''pancake'' and ''saddle,'' were fabricated using the plasma arc process.

Overcoming the Problem of Embedding Change in Educational Organizations: A Perspective from Normalization Process Theory

ERIC Educational Resources Information Center

Wood, Phil

2017-01-01

In this article, I begin by outlining some of the barriers which constrain sustainable organizational change in schools and universities. I then go on to introduce a theory which has already started to help explain complex change and innovation processes in health and care contexts, Normalization Process Theory. Finally, I consider what this…

The Open Method of Coordination and the Implementation of the Bologna Process

ERIC Educational Resources Information Center

Veiga, Amelia; Amaral, Alberto

2006-01-01

In this paper the authors argue that the use of the Open Method of Coordination (OMC) in the implementation of the Bologna process presents coordination problems that do not allow for the full coherence of the results. As the process is quite complex, involving three different levels (European, national and local) and as the final actors in the…

Optimal Mixtures of Test Types in Paired-Associate Learning (Sensory Information Processing). Final Report.

ERIC Educational Resources Information Center

Wolford, George

Seven experiments were run to determine the precise nature of some of the variables which affect the processing of short-term visual information. In particular, retinal location, report order, processing order, lateral masking, and redundancy were studied along with the nature of the confusion errors which are made in the full report procedure.…

"Attrition Processes Out of Mathematics for Undergraduate Students." Attrition from Mathematics as a Social Process. Final Report.

ERIC Educational Resources Information Center

Maines, David R.; And Others

Investigated were those long-term processes which contribute to high rates of attrition for women out of mathematics. It is based on the contention that university students drop out of mathematics as a consequence of prior socialization, educational career contingencies, and goal commitment and career aspirations, with the mix of these factors…

Quality by design case study: an integrated multivariate approach to drug product and process development.

PubMed

Huang, Jun; Kaul, Goldi; Cai, Chunsheng; Chatlapalli, Ramarao; Hernandez-Abad, Pedro; Ghosh, Krishnendu; Nagi, Arwinder

2009-12-01

To facilitate an in-depth process understanding, and offer opportunities for developing control strategies to ensure product quality, a combination of experimental design, optimization and multivariate techniques was integrated into the process development of a drug product. A process DOE was used to evaluate effects of the design factors on manufacturability and final product CQAs, and establish design space to ensure desired CQAs. Two types of analyses were performed to extract maximal information, DOE effect & response surface analysis and multivariate analysis (PCA and PLS). The DOE effect analysis was used to evaluate the interactions and effects of three design factors (water amount, wet massing time and lubrication time), on response variables (blend flow, compressibility and tablet dissolution). The design space was established by the combined use of DOE, optimization and multivariate analysis to ensure desired CQAs. Multivariate analysis of all variables from the DOE batches was conducted to study relationships between the variables and to evaluate the impact of material attributes/process parameters on manufacturability and final product CQAs. The integrated multivariate approach exemplifies application of QbD principles and tools to drug product and process development.

Final Report: Superconducting Joints Between (RE)Ba 2Cu 3O 7-x Coated Conductors via Electric Field Assisted Processing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schwartz, Justin

Here we report the results from a project aimed at developing a fully superconducting joint between two REBCO coated conductors using electric field processing (EFP). Due to a reduction in the budget and time period of this contract, we reduced the project scope and focused first on the key scientific issues for forming a strong bond between conductors, and subsequently focused on improving through-the-joint transport. A modified timeline and task list is shown in Table 1, summarizing accomplishments to date. In the first period, we accomplished initial surface characterization as well as rounds of EFP experiments to begin to understandmore » processing parameters which produce well-bonded tapes. In the second phase, we explored the effects of two fundamental EFP parameters, voltage and pressure, and the limitations they place on the process. In the third phase, we achieved superconducting joints and established base characteristics of both the bonding process and the types of tapes best suited to this process. Finally, we investigated some of the parameters related to kinetics which appeared inhibit joint quality and performance.« less

The dynamics of narrative writing in primary grade children: writing process factors predict story quality.

PubMed

von Koss Torkildsen, Janne; Morken, Frøydis; Helland, Wenche A; Helland, Turid

In this study of third grade school children, we investigated the association between writing process measures recorded with key stroke logging and the final written product. Moreover, we examined the cognitive predictors of writing process and product measures. Analyses of key strokes showed that while most children spontaneously made local online revisions while writing, few revised previously written text. Children with good reading and spelling abilities made more online revisions than their peers. Two process factors, transcription fluency and online revision activity, contributed to explaining variance in narrative macrostructural quality and story length. As for cognitive predictors, spelling was the only factor that gave a unique contribution to explaining variance in writing process factors. Better spelling was associated with more revisions and faster transcription. The results show that developing writers' ability to make online revisions in creative writing tasks is related to both the quality of the final written product and to individual literacy skills. More generally, the findings indicate that investigations of the dynamics of the writing process may provide insights into the factors that contribute to creative writing during early stages of literacy.

Stepwise drying of medicinal plants as alternative to reduce time and energy processing

NASA Astrophysics Data System (ADS)

Cuervo-Andrade, S. P.; Hensel, O.

2016-07-01

The objective of drying medicinal plants is to extend the shelf life and conserving the fresh characteristics. This is achieved by reducing the water activity (aw) of the product to a value which will inhibit the growth and development of pathogenic and spoilage microorganisms, significantly reducing enzyme activity and the rate at which undesirable chemical reactions occur. The technical drying process requires an enormous amount of thermal and electrical energy. An improvement in the quality of the product to be dried and at the same time a decrease in the drying cost and time are achieved through the utilization of a controlled conventional drying method, which is based on a good utilization of the renewable energy or looking for other alternatives which achieve lower processing times without sacrificing the final product quality. In this work the method of stepwise drying of medicinal plants is presented as an alternative to the conventional drying that uses a constant temperature during the whole process. The objective of stepwise drying is the decrease of drying time and reduction in energy consumption. In this process, apart from observing the effects on decreases the effective drying process time and energy, the influence of the different combinations of drying phases on several characteristics of the product are considered. The tests were carried out with Melissa officinalis L. variety citronella, sowed in greenhouse. For the stepwise drying process different combinations of initial and final temperature, 40/50°C, are evaluated, with different transition points associated to different moisture contents (20, 30, 40% and 50%) of the product during the process. Final quality of dried foods is another important issue in food drying. Drying process has effect in quality attributes drying products. This study was determining the color changes and essential oil loses by reference the measurement of the color and essential oil content of the fresh product was used. Drying curves were obtained to observe the dynamics of the process for different combinations of temperature and points of change, corresponding to different conditions of moisture content of the product.

Quality control process improvement of flexible printed circuit board by FMEA

NASA Astrophysics Data System (ADS)

Krasaephol, Siwaporn; Chutima, Parames

2018-02-01

This research focuses on the quality control process improvement of Flexible Printed Circuit Board (FPCB), centred around model 7-Flex, by using Failure Mode and Effect Analysis (FMEA) method to decrease proportion of defective finished goods that are found at the final inspection process. Due to a number of defective units that were found at the final inspection process, high scraps may be escaped to customers. The problem comes from poor quality control process which is not efficient enough to filter defective products from in-process because there is no In-Process Quality Control (IPQC) or sampling inspection in the process. Therefore, the quality control process has to be improved by setting inspection gates and IPCQs at critical processes in order to filter the defective products. The critical processes are analysed by the FMEA method. IPQC is used for detecting defective products and reducing chances of defective finished goods escaped to the customers. Reducing proportion of defective finished goods also decreases scrap cost because finished goods incur higher scrap cost than work in-process. Moreover, defective products that are found during process can reflect the abnormal processes; therefore, engineers and operators should timely solve the problems. Improved quality control was implemented for 7-Flex production lines from July 2017 to September 2017. The result shows decreasing of the average proportion of defective finished goods and the average of Customer Manufacturers Lot Reject Rate (%LRR of CMs) equal to 4.5% and 4.1% respectively. Furthermore, cost saving of this quality control process equals to 100K Baht.

Algorithm for solving of two-level hierarchical minimax program control problem of final state the regional socio-economic system in the presence of risks

NASA Astrophysics Data System (ADS)

Shorikov, A. F.

2017-10-01

In this paper we study the problem of optimization of guaranteed result for program control by the final state of regional social and economic system in the presence of risks. For this problem we propose a mathematical model in the form of two-level hierarchical minimax program control problem of the final state of this process with incomplete information. For solving of its problem we constructed the common algorithm that has a form of a recurrent procedure of solving a linear programming and a finite optimization problems.

Columbia River System Operation Review : Final Environmental Impact Statement, Appendix J: Recreation.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Columbia River System Operation Review

1995-11-01

This Appendix J of the Final Environmental Impact Statement for the Columbia River System discusses impacts on the recreational activities in the region. Major sections include the following: scope and processes; recreation in the Columbia River Basin today - by type, location, participation, user characteristics, factors which affect usage, and managing agencies; recreation analysis procedures and methodology; and alternatives and their impacts.

Practical Approaches to Curriculum Development. A Management Handbook. Project HIRE: A Curriculum Management System for Instructing the Handicapped. Final Report, Volume 2.

ERIC Educational Resources Information Center

Gardner, David C.; Beatty, Grace Joely

Within the context of the major objectives of developing, field testing, and refining the curriculum materials described in volume 1 of this final report (CE 024 117), Volume 2 describes and critiques the management system used by Project HIRE in that development process. (See Note for availability of curriculum materials.) Chapter 1 introduces…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abdelaziz, Omar; Shrestha, Som S.; Shen, Bo

The Oak Ridge National Laboratory (ORNL) High-Ambient-Temperature Evaluation Program for Low-Global Warming Potential (Low-GWP) Refrigerants aims to develop an understanding of the performance of low-GWP alternative refrigerants relative to hydrochlorofluorocarbon (HCFC) and hydrofluorocarbon (HFC) refrigerants in packaged or Rooftop Unit (RTU) air conditioners under high-ambient-temperature conditions. This final report describes the parties involved, the alternative refrigerants selection process, the test procedures, and the final results.

Sampling intensity and normalizations: Exploring cost-driving factors in nationwide mapping of tree canopy cover

Treesearch

John Tipton; Gretchen Moisen; Paul Patterson; Thomas A. Jackson; John Coulston

2012-01-01

There are many factors that will determine the final cost of modeling and mapping tree canopy cover nationwide. For example, applying a normalization process to Landsat data used in the models is important in standardizing reflectance values among scenes and eliminating visual seams in the final map product. However, normalization at the national scale is expensive and...

Fort Benning Land-Use Planning and Management Study

DTIC Science & Technology

1990-04-01

process is three-tiered: (a) an initial phase that results in preliminary allocations for natural resources, (b) a second phase that focuses on...allocations of military training requirements, and (c) a final phase that resolves conflicts between the military and natural resource requirements and...assigns final allocations. 34. Initial phase : Natural resource allocations. The first step in this phase was to make allocations among natural resource

Neuropsychological Assessment and Training of Cognitive Processing Strategies for Reading Recognition and Comprehension: A Computer Assisted Program for Learning Disabled Students. Final Report.

ERIC Educational Resources Information Center

Teeter, Phyllis Anne; Smith, Philip L.

The final report of the 2-year project describes the development and validation of microcomputer software to help assess reading disabled elementary grade children and to provide basic reading instruction. Accomplishments of the first year included: design of the STAR Neuro-Cognitive Assessment Program which includes a reproduction of…

Second Wind: Bringing Good Coping Skills Materials to More Adult Students. Final Narrative Report [and] Coping Skills for Adults Series.

ERIC Educational Resources Information Center

New Educational Projects, Inc., Lancaster, PA.

This document consists of a narrative final project report and the project product, a new edition of five booklets in the "Coping with Crisis" series. The report describes the process of redesigning and repackaging existing adult basic education materials; comments from three students are given. The five booklets are as follows: (1)…

The Costs and Benefits of Testing and Guessing on Recognition Memory

PubMed Central

Huff, Mark J.; Balota, David A.; Hutchison, Keith A.

2016-01-01

We examined whether two types of interpolated tasks (i.e., retrieval-practice via free recall or guessing a missing critical item) improved final recognition for related and unrelated word lists relative to restudying or completing a filler task. Both retrieval-practice and guessing tasks improved correct recognition relative to restudy and filler tasks, particularly when study lists were semantically related. However, both retrieval practice and guessing also generally inflated false recognition for the non-presented critical words. These patterns were found when final recognition was completed during a short delay within the same experimental session (Experiment 1) and following a 24-hr delay (Experiment 2). In Experiment 3, task instructions were presented randomly after each list to determine whether retrieval-practice and guessing effects were influenced by task-expectancy processes. In contrast to Experiments 1 and 2, final recognition following retrieval practice and guessing was equivalent to restudy, suggesting that the observed retrieval-practice and guessing advantages were in part due to preparatory task-based processing during study. PMID:26950490

The effect of mixing ratio variation of sludge and organic solid waste on biodrying process

NASA Astrophysics Data System (ADS)

Nasution, A. C.; Kristanto, G. A.

2018-01-01

In this study, organic waste was co-biodried with sludge cake to determine which mixing ratio gave the best result. The organic waste was consisted of dried leaves and green leaves, while the sludge cake was obtained from a waste water treatment plant in Bekasi. The experiment was performed on 3 lab-scale reactors with same specifications. After 21 days of experiment, it was found that the reactor with the lowest mixing fraction of sludge (5:1) has the best temperature profile and highest moisture content depletion compared with others. Initial moisture content and initial volatile solid content of this reactor’s feedstock was 52.25% and 82.4% respectively. The airflow rate was 10 lpm. After biodrying was done, the final moisture content of the feedstock from Reactor C was 22.0% and the final volatile solid content was 75.9%.The final calorific value after biodrying process was 3179,28kcal/kg.

New high-precision deep concave optical surface manufacturing capability

NASA Astrophysics Data System (ADS)

Piché, François; Maloney, Chris; VanKerkhove, Steve; Supranowicz, Chris; Dumas, Paul; Donohue, Keith

2017-10-01

This paper describes the manufacturing steps necessary to manufacture hemispherical concave aspheric mirrors for high- NA systems. The process chain is considered from generation to final figuring and includes metrology testing during the various manufacturing steps. Corning Incorporated has developed this process by taking advantage of recent advances in commercially available Satisloh and QED Technologies equipment. Results are presented on a 100 mm concave radius nearly hemispherical (NA = 0.94) fused silica sphere with a better than 5 nm RMS figure. Part interferometric metrology was obtained on a QED stitching interferometer. Final figure was made possible by the implementation of a high-NA rotational MRF mode recently developed by QED Technologies which is used at Corning Incorporated for production. We also present results from a 75 mm concave radius (NA = 0.88) Corning ULE sphere that was produced using sub-aperture tools from generation to final figuring. This part demonstrates the production chain from blank to finished optics for high-NA concave asphere.

Final Hanford Comprehensive Land-Use Plan Environmental Impact Statement, Hanford Site, Richland, Washington

DOE Office of Scientific and Technical Information (OSTI.GOV)

N /A

This Final ''Hanford Comprehensive Land-Use Plan Environmental Impact Statement'' (HCP EIS) is being used by the Department of Energy (DOE) and its nine cooperating and consulting agencies to develop a comprehensive land-use plan (CLUP) for the Hanford Site. The DOE will use the Final HCP EIS as a basis for a Record of Decision (ROD) on a CLUP for the Hanford Site. While development of the CLUP will be complete with release of the HCP EIS ROD, full implementation of the CLUP is expected to take at least 50 years. Implementation of the CLUP would begin a more detailed planningmore » process for land-use and facility-use decisions at the Hanford Site. The DOE would use the CLUP to screen proposals. Eventually, management of Hanford Site areas would move toward the CLUP land-use goals. This CLUP process could take more than 50 years to fully achieve the land-use goals.« less

Teachers, Children and the Magical Writing Machine: Instructional Contexts for Word Processing with Learning Disabled Children. Final Report, and "I Know What to Say!" Writing Activities for the Magical Machine.

ERIC Educational Resources Information Center

Morocco, Catherine Cobb; And Others

The 2-year study investigated the use of word processing technology with 36 learning disabled (LD) intermediate grade children and 9 remedial teachers in five Massachusetts school districts. During the first year study staff documented how word processing was being used. In the second year, word processing activities hypothesized to be the most…

Dynamic Resource Allocation to Improve Service Performance in Order Fulfillment Systems

DTIC Science & Technology

2009-01-01

efficient system uses economies of scale at two points: orders are batched before processing, which reduces processing costs, and processed or- ders ...the ef- fects of batching on order picking processes is well-researched and well-understood ( van den Berg and Gademann, 1999). Because orders are...a final so- journ time distribution. Our work builds on existing research in matrix-geometric methods by Neuts (1981), Asmussen and M0ller (2001

Supercritical Fluid Processing of Propellant Polymers

DTIC Science & Technology

1991-01-01

coffee decaffeination , spice extraction, and lipids purification. The processing principles have also long been well known and practiced in the...rn PL-TR-91 -3003 AD: AD-A234 285 Final Report Supercritical Fluid Processing for the period of Propellant Polymers September 1989 to September 1990...PROJECT TASK I’Ac K UNIT ELEMENT NO. NO. P:~53Co O 62302F 5730 0055 3𔃻U-- 11. TITLE (Include Security Classification) Supercritical Fluid Processing

Federal enforcement in group and individual health insurance markets. Final rule.

PubMed

2005-11-25

This rule makes final an interim final rule that details procedures we use for enforcing title XXVII of the Public Health Service Act as added by the Health Insurance Portability and Accountability Act of 1996, and as amended by the Mental Health Parity Act of 1996, the Newborns' and Mothers' Health Protection Act of 1996, and the Women's Health and Cancer Rights Act of 1998. Specifically, we are responsible for enforcing title XXVII requirements in States that do not enact the legislation necessary to enforce those requirements, or otherwise fail to substantially enforce the requirements. We are also responsible for taking enforcement actions against non-Federal governmental plans. The regulation describes the process we use in both enforcement contexts. This final rule deletes an appendix to the interim rule that listed examples of violations of title XXVII and corrects the description of a cross-reference, but makes no substantive changes to the interim final rule.

Memoized Online Variational Inference for Dirichlet Process Mixture Models

DTIC Science & Technology

2014-06-27

breaking process [7], which places artifically large mass on the final component. It is more efficient and broadly applicable than an alternative trunction...models. In Uncertainty in Artificial Intelligence , 2008. [13] N. Le Roux, M. Schmidt, and F. Bach. A stochastic gradient method with an exponential

A Rhetorical Balm: Eulogy for the Challenger.

ERIC Educational Resources Information Center

Klinger-Vartabedian, Laurel

The American space shuttle Challenger's explosion prompted a national grieving process typified by stages of shock, disbelief, acknowledgement, and finally recovery/adaptation. President Reagan's speech on the evening of the disaster assisted this process by integrating content and structure with the psychological needs of the audience. Reagan's…

Project management plan, Waste Receiving and Processing Facility, Module 1, Project W-026

DOE Office of Scientific and Technical Information (OSTI.GOV)

Starkey, J.G.

1993-05-01

The Hanford Waste Receiving and Processing Facility Module 1 Project (WRAP 1) has been established to support the retrieval and final disposal of approximately 400K grams of plutonium and quantities of hazardous components currently stored in drums at the Hanford Site.

Promotion

PubMed Central

Alam, Hasan B.

2013-01-01

This article gives an overview of the promotion process in an academic medical center. A description of different promotional tracks, tenure and endowed chairs, and the process of submitting an application is provided. Finally, some practical advice about developing skills and attributes that can help with academic growth and promotion is dispensed. PMID:24436683

NASA Wallops Flight Center GEOS-3 altimeter data processing report

NASA Technical Reports Server (NTRS)

Stanley, H. R.; Dwyer, R. E.

1980-01-01

The procedures used to process the GEOS-3 radar altimeter data from raw telemetry data to a final user data product are described. In addition, the radar altimeter hardware design and operating parameters are presented to aid the altimeter user in understanding the altimeter data.

76 FR 38419 - United States v. George's Foods, LLC, et. al.; Proposed Final Judgment and Competitive Impact...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-30

...'s'') Harrisonburg, Virginia chicken processing complex, consummated May 7, 2011, violated Section 7... acquisition of Tyson Foods, Inc.'s (``Tyson's'') Harrisonburg, Virginia chicken processing complex..., when Tyson and George's publicly announced George's intent to buy Tyson's Harrisonburg chicken...

UCSD's Automated Merit Processing System.

ERIC Educational Resources Information Center

Merryman, Robert; Johnson, Judy R.; Block, Ron

1998-01-01

The University of California San Diego replaced its manual staff merit-increase-recommendation process with an online computer program to reduce workloads and improve the quality of the final recommendations. The highly successful system has been enthusiastically embraced by the campus community and recognized by the National Association of…

19 CFR 142.43 - Line Release application approval process.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Management. The Office of Information and Technology will review the application and will notify the port... further information, if necessary. An application that fails to elect whether the Line Release transaction... required information is submitted, the application will be forwarded to Headquarters for final processing...

19 CFR 142.43 - Line Release application approval process.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Management. The Office of Information and Technology will review the application and will notify the port... further information, if necessary. An application that fails to elect whether the Line Release transaction... required information is submitted, the application will be forwarded to Headquarters for final processing...

19 CFR 142.43 - Line Release application approval process.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Management. The Office of Information and Technology will review the application and will notify the port... further information, if necessary. An application that fails to elect whether the Line Release transaction... required information is submitted, the application will be forwarded to Headquarters for final processing...

19 CFR 142.43 - Line Release application approval process.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Management. The Office of Information and Technology will review the application and will notify the port... further information, if necessary. An application that fails to elect whether the Line Release transaction... required information is submitted, the application will be forwarded to Headquarters for final processing...

19 CFR 142.43 - Line Release application approval process.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Management. The Office of Information and Technology will review the application and will notify the port... further information, if necessary. An application that fails to elect whether the Line Release transaction... required information is submitted, the application will be forwarded to Headquarters for final processing...

Noise limitations in optical linear algebra processors.

PubMed

Batsell, S G; Jong, T L; Walkup, J F; Krile, T F

1990-05-10

A general statistical noise model is presented for optical linear algebra processors. A statistical analysis which includes device noise, the multiplication process, and the addition operation is undertaken. We focus on those processes which are architecturally independent. Finally, experimental results which verify the analytical predictions are also presented.

Cleaning Processes across NASA Centers

NASA Technical Reports Server (NTRS)

Hammond, John M.

2010-01-01

All significant surfaces of the hardware must be pre-cleaned to remove dirt, grit, scale, corrosion, grease, oil and other foreign matter prior to any final precision cleaning process. Metallic parts shall be surface treated (cleaned, passivated, pickled and/or coated) as necessary to prevent latent corrosion and contamination.

14 CFR 21.143 - Quality control data requirements; prime manufacturer.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., purchased items, and parts and assemblies produced by manufacturers' suppliers including methods used to... special manufacturing processes involved, the means used to control the processes, the final test... procedure for recording review board decisions and disposing of rejected parts; (5) An outline of a system...

Faculty Return to Industry. Final Report.

ERIC Educational Resources Information Center

Hulse, David R.

Lagging productivity and increased competitiveness from abroad are forcing U.S. management companies to adopt new management styles that promote efficiency and quality in production. High on the agenda is the incorporation of Statistical Process Control (SPC). SPC requires definition of process and product specifications to facilitate their…

76 FR 44464 - Process for Review of Swaps for Mandatory Clearing

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-26

... COMMODITY FUTURES TRADING COMMISSION 17 CFR Parts 39 and 140 RIN 3038-AD00 Process for Review of Swaps for Mandatory Clearing AGENCY: Commodity Futures Trading Commission. ACTION: Final rule. SUMMARY: The Commodity Futures Trading Commission (Commission or CFTC) is adopting regulations to implement...

KSC-2009-2320

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – In the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida, technicians check the fit of the end cover on the Ares I-X motor segment. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

KSC-2009-2321

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – In the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida, the open end of the Ares I-X motor segment is seen without the end cover. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

KSC-2009-2319

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – In the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida, a technician begins propellant grain inspection of the interior of the Ares I-X motor segment. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

KSC-2009-2316

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – In the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida, the Ares I-X motor segment waits for inspection after removal of the shipping container. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

KSC-2009-2322

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – In the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida, a technician performs propellant grain inspection of the inside of the Ares I-X motor segment. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

KSC-2009-2314

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – In the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida, the rail car cover is moved away from the first Ares I-X motor segment. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

KSC-2009-2315

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – In the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida, the Ares I-X motor segment is revealed after removal of the rail car cover. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

KSC-2009-2313

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – In the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida, the rail car cover is removed from the first Ares I-X motor segment. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

KSC-2009-2312

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – In the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida, the rail car cover is removed from the first Ares I-X motor segment. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

Mitigation Strategies To Protect Food Against Intentional Adulteration. Final rule.

PubMed

2016-05-27

The Food and Drug Administration (FDA or we) is issuing this final rule to require domestic and foreign food facilities that are required to register under the Federal Food, Drug, and Cosmetic Act (the FD&C Act) to address hazards that may be introduced with the intention to cause wide scale public health harm. These food facilities are required to conduct a vulnerability assessment to identify significant vulnerabilities and actionable process steps and implement mitigation strategies to significantly minimize or prevent significant vulnerabilities identified at actionable process steps in a food operation. FDA is issuing these requirements as part of our implementation of the FDA Food Safety Modernization Act (FSMA).

Altimeter waveform software design

NASA Technical Reports Server (NTRS)

Hayne, G. S.; Miller, L. S.; Brown, G. S.

1977-01-01

Techniques are described for preprocessing raw return waveform data from the GEOS-3 radar altimeter. Topics discussed include: (1) general altimeter data preprocessing to be done at the GEOS-3 Data Processing Center to correct altimeter waveform data for temperature calibrations, to convert between engineering and final data units and to convert telemetered parameter quantities to more appropriate final data distribution values: (2) time "tagging" of altimeter return waveform data quantities to compensate for various delays, misalignments and calculational intervals; (3) data processing procedures for use in estimating spacecraft attitude from altimeter waveform sampling gates; and (4) feasibility of use of a ground-based reflector or transponder to obtain in-flight calibration information on GEOS-3 altimeter performance.

Inclusive π+d →p (η p ) process and the η N scattering length

NASA Astrophysics Data System (ADS)

Garcilazo, Humberto

2018-02-01

The cross section of the inclusive process π+d →p (η p ) is calculated as a function of the η p invariant mass when the detected proton is moving in the forward direction. The incident pion has a momentum of plab=898.47 MeV/c for which the η p pair are left at rest in the laboratory system which allows one to study the effect of the η p →η p final-state interaction in the region of the N (1535 ) S11 resonance. The sensitivity of the inclusive cross section to different parametrizations of the η N final-state interaction is discussed.

Permanent certification program for health information technology; revisions to ONC-Approved Accreditor processes. Final rule.

PubMed

2011-11-25

Under the authority granted to the National Coordinator for Health Information Technology by section 3001(c)(5) of the Public Health Service Act (PHSA) as added by the Health Information Technology for Economic and Clinical Health (HITECH) Act, this final rule establishes a process for addressing instances where the ONC-Approved Accreditor (ONC-AA) engages in improper conduct or does not perform its responsibilities under the permanent certification program. This rule also addresses the status of ONC-Authorized Certification Bodies (ONC-ACBs) in instances where there may be a change in the accreditation organization serving as the ONC-AA and clarifies the responsibilities of the new ONC-AA.

Approaches to self-assembly of colloidal monolayers: A guide for nanotechnologists.

PubMed

Lotito, Valeria; Zambelli, Tomaso

2017-08-01

Self-assembly of quasi-spherical colloidal particles in two-dimensional (2D) arrangements is essential for a wide range of applications from optoelectronics to surface engineering, from chemical and biological sensing to light harvesting and environmental remediation. Several self-assembly approaches have flourished throughout the years, with specific features in terms of complexity of the implementation, sensitivity to process parameters, characteristics of the final colloidal assembly. Selecting the proper method for a given application amidst the vast literature in this field can be a challenging task. In this review, we present an extensive classification and comparison of the different techniques adopted for 2D self-assembly in order to provide useful guidelines for scientists approaching this field. After an overview of the main applications of 2D colloidal assemblies, we describe the main mechanisms underlying their formation and introduce the mathematical tools commonly used to analyse their final morphology. Subsequently, we examine in detail each class of self-assembly techniques, with an explanation of the physical processes intervening in crystallization and a thorough investigation of the technical peculiarities of the different practical implementations. We point out the specific characteristics of the set-ups and apparatuses developed for self-assembly in terms of complexity, requirements, reproducibility, robustness, sensitivity to process parameters and morphology of the final colloidal pattern. Such an analysis will help the reader to individuate more easily the approach more suitable for a given application and will draw the attention towards the importance of the details of each implementation for the final results. Copyright © 2017 Elsevier B.V. All rights reserved.

Photoinitiated Polymerization-Induced Self-Assembly (Photo-PISA): New Insights and Opportunities.

PubMed

Yeow, Jonathan; Boyer, Cyrille

2017-07-01

The polymerization-induced self-assembly (PISA) process is a useful synthetic tool for the efficient synthesis of polymeric nanoparticles of different morphologies. Recently, studies on visible light initiated PISA processes have offered a number of key research opportunities that are not readily accessible using traditional thermally initiated systems. For example, visible light mediated PISA (Photo-PISA) enables a high degree of control over the dispersion polymerization process by manipulation of the wavelength and intensity of incident light. In some cases, the final nanoparticle morphology of a single formulation can be modulated by simple manipulation of these externally controlled parameters. In addition, temporal (and in principle spatial) control over the Photo-PISA process can be achieved in most cases. Exploitation of the mild room temperature polymerizations conditions can enable the encapsulation of thermally sensitive therapeutics to occur without compromising the polymerization rate and their activities. Finally, the Photo-PISA process can enable further mechanistic insights into the morphological evolution of nanoparticle formation such as the effects of temperature on the self-assembly process. The purpose of this mini-review is therefore to examine some of these recent advances that have been made in Photo-PISA processes, particularly in light of the specific advantages that may exist in comparison with conventional thermally initiated systems.

Ceramification: A plutonium immobilization process

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rask, W.C.; Phillips, A.G.

1996-05-01

This paper describes a low temperature technique for stabilizing and immobilizing actinide compounds using a combination process/storage vessel of stainless steel, in which measured amounts of actinide nitrate solutions and actinide oxides (and/or residues) are systematically treated to yield a solid article. The chemical ceramic process is based on a coating technology that produces rare earth oxide coatings for defense applications involving plutonium. The final product of this application is a solid, coherent actinide oxide with process-generated encapsulation that has long-term environmental stability. Actinide compounds can be stabilized as pure materials for ease of re-use or as intimate mixtures withmore » additives such as rare earth oxides to increase their degree of proliferation resistance. Starting materials for the process can include nitrate solutions, powders, aggregates, sludges, incinerator ashes, and others. Agents such as cerium oxide or zirconium oxide may be added as powders or precursors to enhance the properties of the resulting solid product. Additives may be included to produce a final product suitable for use in nuclear fuel pellet production. The process is simple and reduces the time and expense for stabilizing plutonium compounds. It requires a very low equipment expenditure and can be readily implemented into existing gloveboxes. The process is easily conducted with less associated risk than proposed alternative technologies.« less

Photoinitiated Polymerization‐Induced Self‐Assembly (Photo‐PISA): New Insights and Opportunities

PubMed Central

Yeow, Jonathan

2017-01-01

The polymerization‐induced self‐assembly (PISA) process is a useful synthetic tool for the efficient synthesis of polymeric nanoparticles of different morphologies. Recently, studies on visible light initiated PISA processes have offered a number of key research opportunities that are not readily accessible using traditional thermally initiated systems. For example, visible light mediated PISA (Photo‐PISA) enables a high degree of control over the dispersion polymerization process by manipulation of the wavelength and intensity of incident light. In some cases, the final nanoparticle morphology of a single formulation can be modulated by simple manipulation of these externally controlled parameters. In addition, temporal (and in principle spatial) control over the Photo‐PISA process can be achieved in most cases. Exploitation of the mild room temperature polymerizations conditions can enable the encapsulation of thermally sensitive therapeutics to occur without compromising the polymerization rate and their activities. Finally, the Photo‐PISA process can enable further mechanistic insights into the morphological evolution of nanoparticle formation such as the effects of temperature on the self‐assembly process. The purpose of this mini‐review is therefore to examine some of these recent advances that have been made in Photo‐PISA processes, particularly in light of the specific advantages that may exist in comparison with conventional thermally initiated systems. PMID:28725534

Pre-polishing on a CNC platform with bound abrasive contour tools

NASA Astrophysics Data System (ADS)

Schoeffer, Adrienne E.

2003-05-01

Deterministic micorgrinding (DMG) of optical glasses and ceramics is the commercial manufacturing process of choice to shape glass surfaces prior to final finishing. This process employs rigid bound matrix diamond tooling resulting in surface roughness values of 3-51.tm peak to valley and 100-400nm rms, as well as mid-spatial frequency tool marks that require subsequent removal in secondary finishing steps. The ability to pre-polish optical surfaces within the grinding platform would reduce final finishing process times. Bound abrasive contour wheels containing cerium oxide, alumina or zirconia abrasives were constructed with an epoxy matrix. The effects of abrasive type, composition, and erosion promoters were examined for tool hardness (Shore D), and tested with commercial optical glasses in an OptiproTM CNC grinding platform. Metrology protocols were developed to examine tool wear and subsequent surface roughness. Work is directed to demonstrating effective material removal, improved surface roughness and cutter mark removal.

Prepolishing on a CNC platform with bound abrasive contour tools

NASA Astrophysics Data System (ADS)

Schoeffler, Adrienne E.; Gregg, Leslie L.; Schoen, John M.; Fess, Edward M.; Hakiel, Michael; Jacobs, Stephen D.

2003-05-01

Deterministic microgrinding (DMG) of optical glasses and ceramics is the commercial manufacturing process of choice to shape glass surfaces prior to final finishing. This process employs rigid bound matrix diamond tooling resulting in surface roughness values of 3-5μm peak to valley and 100-400nm rms, as well as mid-spatial frequency tool marks that require subsequent removal in secondary finishing steps. The ability to pre-polish optical surfaces within the grinding platform would reduce final finishing process times. Bound abrasive contour wheels containing cerium oxide, alumina or zirconia abrasives were constructed with an epoxy matrix. The effects of abrasive type, composition, and erosion promoters were examined for tool hardness (Shore D), and tested with commercial optical glasses in an Optipro CNC grinding platform. Metrology protocols were developed to examine tool wear and subsequent surface roughness. Work is directed to demonstrating effective material removal, improved surface roughness and cutter mark removal.