Centroacinar cells: At the center of pancreas regeneration.

PubMed

Beer, Rebecca L; Parsons, Michael J; Rovira, Meritxell

2016-05-01

The process of regeneration serves to heal injury by replacing missing cells. Understanding regeneration can help us replace cell populations lost during disease, such as the insulin-producing β cells lost in diabetic patients. Centroacinar cells (CACs) are a specialized ductal pancreatic cell type that act as progenitors to replace β cells in the zebrafish. However, whether CACs contribute to β-cell regeneration in adult mammals remains controversial. Here we review the current understanding of the role of CACs as endocrine progenitors during regeneration in zebrafish and mammals. Copyright © 2016 Elsevier Inc. All rights reserved.

46 CFR 10.229 - Replacement of lost merchant mariner credentials.

Code of Federal Regulations, 2014 CFR

2014-10-01

... expiration date as the lost credential. The duplicate issued will be in the form of an MMC. Until April 15... collision, explosion, tornado, wreck, flooding, beaching, grounding, or fire; or personal loss associated...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brauner, Edwin Jr.; Carlson, Daniel C.

The Geysers steamfields in northern Sonoma County have produced reliable ''green'' power for many years. An impediment to long-term continued production has been the ability to provide a reliable source of injection water to replace water extracted and lost in the form of steam. The steamfield operators have historcially used cooling towers to recycle a small portion of the steam and have collected water during the winter months using stream extraction. These two sources, however, could not by themselves sustain the steamfield in the long term. The Lake County Reclaimed Water Project (SEGEP) was inititated in 1997 and provides anothermore » source of steamfield replenishment water. The Santa Rosa Geysers Recharge Project provides another significant step in replenishing the steamfield. In addition, the Santa Rosa Geysers Recharge Project has been built with capacity to potentially meet virtually all injection water requirements, when combined with these other sources. Figure 2.1 graphically depicts the combination of injection sources.« less

47 CFR 13.17 - Replacement license.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Replacement license. 13.17 Section 13.17 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL RADIO OPERATORS General § 13.17 Replacement license. (a) Each licensee or permittee whose original document is lost, mutilated, or destroyed must...

The lifetime direct cost of periodontal treatment: a case study from a Norwegian specialist practice.

PubMed

Fardal, Øystein; O'Neill, Ciaran; Gjermo, Per; Fardal, Elizabeth; Sandvik, Leiv; Hansen, B Frode; Linden, Gerard J

2012-12-01

Successful periodontal treatment requires a commitment to regular lifelong maintenance and may be perceived by patients to be costly. This study calculates the total lifetime cost of periodontal treatment in the setting of a specialist periodontal practice and investigates the cost implications of choosing not to proceed with such treatment. Data from patients treated in a specialist practice in Norway were used to calculate the total lifetime cost of periodontal treatment that included baseline periodontal treatment, regular maintenance, retreatment, and replacing teeth lost during maintenance. Incremental costs for alternative strategies based on opting to forego periodontal treatment or maintenance and to replace any teeth lost with either bridgework or implants were calculated. Patients who completed baseline periodontal treatment but did not have any additional maintenance or retreatment could replace only three teeth with bridgework or two teeth with implants before the cost of replacing additional teeth would exceed the cost of lifetime periodontal treatment. Patients who did not have any periodontal treatment could replace ≤ 4 teeth with bridgework or implants before a replacement strategy became more expensive. Within the limits of the assumptions made, periodontal treatment in a Norwegian specialist periodontal practice is cost-effective when compared to an approach that relies on opting to replace teeth lost as a result of progressive periodontitis with fixed restorations. In particular, patients who have initial comprehensive periodontal treatment but do not subsequently comply with maintenance could, on average, replace ≤ 3 teeth with bridgework or two teeth with implants before this approach would exceed the direct cost of lifetime periodontal treatment in the setting of the specialist practice studied.

Capturing the lost phosphorus.

PubMed

Rittmann, Bruce E; Mayer, Brooke; Westerhoff, Paul; Edwards, Mark

2011-08-01

Minable phosphorus (P) reserves are being depleted and will need to be replaced by recovering P that currently is lost from the agricultural system, causing water-quality problems. The largest two flows of lost P are in agricultural runoff and erosion (∼46% of mined P globally) and animal wastes (∼40%). These flows are quite distinct. Runoff has a very high volumetric flow rate, but a low P concentration; animal wastes have low flow rates, but a high P concentration together with a high concentration of organic material. Recovering the lost P in animal wastes is technically and economically more tractable, and it is the focus for this review of promising P-capture technologies. P capture requires that organic P be transformed into inorganic P (phosphate). For high-strength animal wastes, P release can be accomplished in tandem with anaerobic treatment that converts the energy value in the organic matter to CH(4), H(2), or electricity. Once present as phosphate, the P can be captured in a reusable form by four approaches. Most well developed is precipitation as magnesium or calcium solids. Less developed, but promising are adsorption to iron-based adsorbents, ion exchange to phosphate-selective solids, and uptake by photosynthetic microorganisms or P-selective proteins. Copyright © 2011 Elsevier Ltd. All rights reserved.

A Mobilization Preparedness Primer for Water Management at Ammunition Plants.

DTIC Science & Technology

1985-12-02

7: TABLE OF CONTENTS Section Page Why .................................. 4 The Water Cycle ....................... 5 V4o1...management? A checklist of telltale signs is given. - ’..-. 4 *.. *. *. *.< The Water Cycle Looking at the earth from an orbiting satellite confirms...production, a battle was lost Because of battles lost, a war was lost Because a war was lost, freedom was lost Your orientation begins with the water

Stem cell treatment of degenerative eye disease.

PubMed

Mead, Ben; Berry, Martin; Logan, Ann; Scott, Robert A H; Leadbeater, Wendy; Scheven, Ben A

2015-05-01

Stem cell therapies are being explored extensively as treatments for degenerative eye disease, either for replacing lost neurons, restoring neural circuits or, based on more recent evidence, as paracrine-mediated therapies in which stem cell-derived trophic factors protect compromised endogenous retinal neurons from death and induce the growth of new connections. Retinal progenitor phenotypes induced from embryonic stem cells/induced pluripotent stem cells (ESCs/iPSCs) and endogenous retinal stem cells may replace lost photoreceptors and retinal pigment epithelial (RPE) cells and restore vision in the diseased eye, whereas treatment of injured retinal ganglion cells (RGCs) has so far been reliant on mesenchymal stem cells (MSC). Here, we review the properties of non-retinal-derived adult stem cells, in particular neural stem cells (NSCs), MSC derived from bone marrow (BMSC), adipose tissues (ADSC) and dental pulp (DPSC), together with ESC/iPSC and discuss and compare their potential advantages as therapies designed to provide trophic support, repair and replacement of retinal neurons, RPE and glia in degenerative retinal diseases. We conclude that ESCs/iPSCs have the potential to replace lost retinal cells, whereas MSC may be a useful source of paracrine factors that protect RGC and stimulate regeneration of their axons in the optic nerve in degenerate eye disease. NSC may have potential as both a source of replacement cells and also as mediators of paracrine treatment. Copyright © 2015. Published by Elsevier B.V.

Effect of severe hurricanes on biorock coral reef restoration projects in Grand Turk, Turks and Caicos Islands.

PubMed

Wells, Lucy; Perez, Fernando; Hibbert, Marlon; Clerveaux, Luc; Johnson, Jodi; Goreau, Thomas J

2010-10-01

Artificial reefs are often discouraged in shallow waters over concerns of storm damage to structures and surrounding habitat. Biorock coral reef restoration projects were initiated in waters around 5 m deep in Grand Turk, at Oasis (October 2006) and at Governor's Beach (November 2007). Hemi-cylindrical steel modules, 6m long were used, four modules at Oasis and six at Governor's Beach. Each project has over 1200 corals transplanted from sites with high sedimentation damage, and are regularly monitored for coral growth, mortality and fish populations. Corals show immediate growth over wires used to attach corals. Growth has been measured from photographs using a software program and is faster at Governor's Beach. After hurricanes Hanna and Ike (September 2008) the Governor's Beach structure was fully standing since the waves passed straight through with little damage, the Oasis structures which were tie-wired rather than welded had one module collapse (since been replaced with a new, welded structure). Hurricane Ike was the strongest hurricane on record to hit Grand Turk. Most cables were replaced following the hurricanes due to damage from debris and high wave action. The projects lost about a third of the corals due to hurricanes. Most of those lost had only been wired a few days before and had not yet attached themselves firmly. These projects have regenerated corals and fish populations in areas of barren sand or bedrock and are now attractive to snorkelers. High coral survival and low structural damage after hurricanes indicate that Biorock reef restoration can be effective in storm-impacted areas.

14 CFR 47.49 - Replacement of Certificate.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AIRCRAFT REGISTRATION Certificates of Aircraft Registration § 47.49 Replacement of Certificate. (a) If the original Certificate of Aircraft Registration, AC Form 8050-3, is lost, stolen, or mutilated, the... owner. (b) The registered owner may request a temporary Certificate of Aircraft Registration pending...

14 CFR 47.49 - Replacement of Certificate.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AIRCRAFT REGISTRATION Certificates of Aircraft Registration § 47.49 Replacement of Certificate. (a) If the original Certificate of Aircraft Registration, AC Form 8050-3, is lost, stolen, or mutilated, the... owner. (b) The registered owner may request a temporary Certificate of Aircraft Registration pending...

14 CFR 47.49 - Replacement of Certificate.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AIRCRAFT REGISTRATION Certificates of Aircraft Registration § 47.49 Replacement of Certificate. (a) If the original Certificate of Aircraft Registration, AC Form 8050-3, is lost, stolen, or mutilated, the... owner. (b) The registered owner may request a temporary Certificate of Aircraft Registration pending...

14 CFR 47.49 - Replacement of Certificate.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AIRCRAFT REGISTRATION Certificates of Aircraft Registration § 47.49 Replacement of Certificate. (a) If the original Certificate of Aircraft Registration, AC Form 8050-3, is lost, stolen, or mutilated, the... owner. (b) The registered owner may request a temporary Certificate of Aircraft Registration pending...

Aqueous NMR Signal Enhancement by Reversible Exchange in a Single Step Using Water-Soluble Catalysts

PubMed Central

2016-01-01

Two synthetic strategies are investigated for the preparation of water-soluble iridium-based catalysts for NMR signal amplification by reversible exchange (SABRE). In one approach, PEGylation of a variant N-heterocyclic carbene provided a novel catalyst with excellent water solubility. However, while SABRE-active in ethanol solutions, the catalyst lost activity in >50% water. In a second approach, synthesis of a novel di-iridium complex precursor where the cyclooctadiene (COD) rings have been replaced by CODDA (1,2-dihydroxy-3,7-cyclooctadiene) leads to the creation of a catalyst [IrCl(CODDA)IMes] that can be dissolved and activated in water—enabling aqueous SABRE in a single step, without need for either an organic cosolvent or solvent removal followed by aqueous reconstitution. The potential utility of the CODDA catalyst for aqueous SABRE is demonstrated with the ∼(−)32-fold enhancement of 1H signals of pyridine in water with only 1 atm of parahydrogen. PMID:27350846

Cost Analysis of Utilizing Electric Vehicles and Photovoltaic Solar Energy in the United States Marine Corps Commercial Vehicle Fleet

DTIC Science & Technology

2009-12-01

vehicles so do some electric vehicle braking systems (MIT, 2008). e. Brakes Regenerative braking on electric vehicles recoups some of the energy lost...engine is required to replace the energy lost by braking . Regenerative braking takes some of the lost energy during braking and turns it into...Motors and Tesla Motors offer regenerative breaking in their respective electric vehicles. Tesla explains regenerative braking as “engine braking

14 CFR 47.49 - Replacement of Certificate.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AIRCRAFT REGISTRATION Certificates of Aircraft Registration § 47.49 Replacement of Certificate. (a) If a Certificate of Aircraft Registration is lost, stolen, or mutilated, the holder of the Certificate of Aircraft Registration may apply to the FAA Aircraft Registry for a duplicate certificate, accompanying his application...

Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters.

PubMed

Tetteh, Paul W; Basak, Onur; Farin, Henner F; Wiebrands, Kay; Kretzschmar, Kai; Begthel, Harry; van den Born, Maaike; Korving, Jeroen; de Sauvage, Frederic; van Es, Johan H; van Oudenaarden, Alexander; Clevers, Hans

2016-02-04

Intestinal crypts display robust regeneration upon injury. The relatively rare secretory precursors can replace lost stem cells, but it is unknown if the abundant enterocyte progenitors that express the Alkaline phosphate intestinal (Alpi) gene also have this capacity. We created an Alpi-IRES-CreERT2 (Alpi(CreER)) knockin allele for lineage tracing. Marked clones consist entirely of enterocytes and are all lost from villus tips within days. Genetic fate-mapping of Alpi(+) cells before or during targeted ablation of Lgr5-expressing stem cells generated numerous long-lived crypt-villus "ribbons," indicative of dedifferentiation of enterocyte precursors into Lgr5(+) stems. By single-cell analysis of dedifferentiating enterocytes, we observed the generation of Paneth-like cells and proliferative stem cells. We conclude that the highly proliferative, short-lived enterocyte precursors serve as a large reservoir of potential stem cells during crypt regeneration. Copyright © 2016 Elsevier Inc. All rights reserved.

Financial vulnerability of the electricity sector to drought, and the impacts of changes in generation mix

NASA Astrophysics Data System (ADS)

Kern, J.

2015-12-01

Electric power utilities are increasingly cognizant of the risks water scarcity and rising temperatures pose for generators that use water as a "fuel" (i.e., hydroelectric dams) and generators that use water for cooling (i.e., coal, natural gas and nuclear). At the same time, utilities are under increasing market and policy pressure to retire coal-fired generation, the primary source of carbon emissions in the electric power sector. Due to falling costs of renewables and low natural gas prices, retiring coal fired generation is mostly being replaced with combined cycle natural gas, wind and solar. An immediate benefit of this shift has been a reduction in water withdrawals per megawatt-hour and reduced thermal impacts in surface water systems. In the process of retiring older coal-fired power plants, many of which use water intensive open-loop cooling systems, utilities are making their systems less vulnerable to water scarcity and higher water temperatures. However, it is not clear whether financial risks from water scarcity will decrease as result of this change. In particular, the choice to replace coal with natural gas combined cycle plants leaves utilities financially exposed to natural gas prices, especially during droughts when natural gas generation is used to replace lost hydropower production. Utility-scale solar, while more expensive than natural gas combined cycle generation, gives utilities an opportunity to simultaneously reduce their exposure to water scarcity and fuel price risk. In this study, we assess how switching from coal to natural gas and solar changes a utility's financial exposure to drought. We model impacts on retail prices and a utility's rate of return under current conditions and non-stationarity in natural gas prices and temperature and streamflows to determine whether increased exposure to natural gas prices offsets corresponding gains in water use efficiency. We also evaluate whether utility scale solar is an effective hedge against the combined effects of drought and natural gas price volatility—one that increases costs on average but reduces exposure to large drought-related losses.

Climate-driven regime shift of a temperate marine ecosystem.

PubMed

Wernberg, Thomas; Bennett, Scott; Babcock, Russell C; de Bettignies, Thibaut; Cure, Katherine; Depczynski, Martial; Dufois, Francois; Fromont, Jane; Fulton, Christopher J; Hovey, Renae K; Harvey, Euan S; Holmes, Thomas H; Kendrick, Gary A; Radford, Ben; Santana-Garcon, Julia; Saunders, Benjamin J; Smale, Dan A; Thomsen, Mads S; Tuckett, Chenae A; Tuya, Fernando; Vanderklift, Mathew A; Wilson, Shaun

2016-07-08

Ecosystem reconfigurations arising from climate-driven changes in species distributions are expected to have profound ecological, social, and economic implications. Here we reveal a rapid climate-driven regime shift of Australian temperate reef communities, which lost their defining kelp forests and became dominated by persistent seaweed turfs. After decades of ocean warming, extreme marine heat waves forced a 100-kilometer range contraction of extensive kelp forests and saw temperate species replaced by seaweeds, invertebrates, corals, and fishes characteristic of subtropical and tropical waters. This community-wide tropicalization fundamentally altered key ecological processes, suppressing the recovery of kelp forests. Copyright © 2016, American Association for the Advancement of Science.

The Replacement Child: Substitution of a Lost Family Member.

ERIC Educational Resources Information Center

Denton, Roy T.; Green, Donald

Patterns of successful and unsuccessful resolution of grief over death of a child were studied in 25 families who had lost children across an 11-year-span. The families varied considerably in age, income, education, and parental occupation. Data were gathered by means of an intensive, open-ended interview schedule. The research focused on two…

The T-Shaped Graduate

ERIC Educational Resources Information Center

Ramaswami, Rama

2009-01-01

As President Obama said in advance remarks about the American Graduation Initiative: "[T]he hard truth is that some of the jobs that have been lost in the auto industry and elsewhere won't be coming back. And that only underscores the importance of generating new businesses and industries to replace the ones we've lost, and of preparing our…

Use of created cattail ( Typha) wetlands in mitigation strategies

NASA Astrophysics Data System (ADS)

Dobberteen, Ross A.; Nickerson, Norton H.

1991-11-01

In order to balance pressures for land-use development with protection of wetland resources, artificial wetlands have been constructed in an effort to replace lost ecosystems. Despite its regulatory appeal and prominent role in current mitigation strategies, it is unclear whether or not created systems actually compensate for lost wetland resources. Mitigation predictions that rely on artificial wetlands must be analyzed critically in terms of their efficacy. Destruction of wetlands due to burial by coal fly ash at a municipal landfill in Danvers, Massachusetts, USA, provided an opportunity to compare resulting growth of created cattail ( Typha) marshes with natural wetland areas. Once the appropriate cattail species was identified for growth under disturbed landfill conditions, two types of artificial wetlands were constructed. The two systems differed in their hydrologic attributes: while one had a surface water flow characteristic of most cattail wetlands, the second system mimicked soil and water conditions found in naturally occurring floating cattail marshes. Comparison of plant growth measurements for two years from the artificial systems with published values for natural cattail marshes revealed similar structure and growth patterns. Experiments are now in progress to investigate the ability of created cattail marshes to remove and accumulate heavy metals from polluted landfill leachate. Research of the type reported here must be pursued aggressively in order to document the performance of artificial wetlands in terms of plant structure and wetland functions. Such research should allow us to start to evaluate whether artificial systems actually compensate for lost wetlands by performing similar functions and providing the concomitant public benefits.

Aquifer-test results, direction of ground-water flow, and 1984-90 annual ground-water pumpage for irrigation, lower Big Lost River Valley, Idaho

USGS Publications Warehouse

Bassick, M.D.; Jones, M.L.

1992-01-01

The study area (see index map of Idaho), part of the Big Lost River drainage basin, is at the northern side of the eastern Snake River Plain. The lower Big Lost River Valley extends from the confluence of Antelope Creek and the Big Lost River to about 4 mi south of Arco and encompasses about 145 mi2 (see map showing water-level contours). The study area is about 18 mi long and, at its narrowest, 4 mi wide. Arco, Butte City, and Moore, with populations of 1,016, 59, and 190, respectively, in 1990, are the only incorporated towns. The entire study area, except the extreme northwestern part, is in Butte City. The study area boundary is where alluvium and colluvium pinch out and abut against the White Knob Mountains (chiefly undifferentiated sedimentary rock with lesser amounts of volcanic rock) on the west and the Lost River Range (chiefly sedimentary rock) on the east. Gravel and sand in the valley fill compose the main aquifer. The southern boundary is approximately where Big Lost River valley fill intercalates with or abuts against basalt of the Snake River Group. Spring ground-water levels and flow in the Big Lost River depend primarily on temperature and the amount and timing of precipitation within the entire drainage basin. Periods of abundant water supply and water shortages are, therefore, related to the amount of annual precipitation. Surface reservoir capacity in the valley (Mackay Reservoir, about 20 mi northwest of Moore) is only 20 percent of the average annual flow of the Big Lost River (Crosthwaite and others, 1970, p. 3). Stored surface water is generally unavailable for carryover from years of abundant water supply to help relieve drought conditions in subsequent years. Many farmers have drilled irrigation wells to supplement surface-water supplies and to increase irrigated acreage. Average annual flow of the Big Lost River below Mackay Reservoir near Mackay (gaging station 13127000, not shown) in water years 1905, 1913-14, and 1920-90 was about 224,600 acre-ft; average annual flow of the Big Lost River near Arco (gaging station 13132500; see map showing water-level contours) in water years 1947-61, 1967-80, and 1983-90 was about 79,000 acre-ft (Harenberg and others, 1991, p. 254-255). Moore Canal and East Side Ditch divert water from the Big Lost River at the Moore Diversion, 3 mi north of Moore (see map showing water-level contours) and supply water for irrigation near the margins of the valley. When water supply is average or greater, water in the Big Lost River flows through the study area and onto the Snake River Plain, where it evaporates or infiltrates into the Snake River Plain aquifer. When water supply is below average, water in the Big Lost River commonly does not reach Arco; rather, it is diverted for irrigation in the interior of the valley, evaporates, or infiltrates to the valley-fill aquifer. This report describes the results of a study by the U.S. Geological Survey, in cooperation with the Idaho Department of Water Resources, to collect hydrologic data needed to help address water-supply problems in the Big Lost River Valley. Work involved (1) field inventory of 81 wells, including 46 irrigation wells; (2) measurement of water levels in 154 wells in March 1991; (3) estimation of annual ground-water pumpage for irrigation from 1984 through 1990; and (4) analysis of results of an aquifer test conducted southwest of Moore. All data obtained during this study may be inspected at the U.S. Geological Survey, Idaho District office, Boise.

Hungry Horse Dam Fisheries Mitigation; Kokanee Stocking and Monitoring in Flathead Lake, 1995 Annual Report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fredenberg, Wade; Carty, Daniel; Cavigli, Jon

1996-06-01

The operation of Hungry Horse Dam on the South Fork-of the Flathead River reduced the reproductive success of kokanee (Oncorhynchus nerka) spawning in the Flathead River. Montana Fish, Wildlife and Parks (MFWP) and the Confederated Salish and Kootenai Tribes (CSKT) authored a mitigation plan to offset those losses. The mitigation goal, stated in the Fisheries Mitigation Plan for Losses Attributed to the Construction and Operation of Hungry Horse Dam, is to: {open_quotes}Replace lost annual production of 100,000 kokanee adults, initially through hatchery production and pen rearing in Flathead Lake, partially replacing lost forage for lake trout (Salvelinus namaycush) in Flatheadmore » Lake.{close_quotes}« less

Optimizing the restoration and maintenance of fluid balance after exercise-induced dehydration.

PubMed

Evans, Gethin H; James, Lewis J; Shirreffs, Susan M; Maughan, Ronald J

2017-04-01

Hypohydration, or a body water deficit, is a common occurrence in athletes and recreational exercisers following the completion of an exercise session. For those who will undertake a further exercise session that day, it is important to replace water losses to avoid beginning the next exercise session hypohydrated and the potential detrimental effects on performance that this may lead to. The aim of this review is to provide an overview of the research related to factors that may affect postexercise rehydration. Research in this area has focused on the volume of fluid to be ingested, the rate of fluid ingestion, and fluid composition. Volume replacement during recovery should exceed that lost during exercise to allow for ongoing water loss; however, ingestion of large volumes of plain water results in a prompt diuresis, effectively preventing longer-term maintenance of water balance. Addition of sodium to a rehydration solution is beneficial for maintenance of fluid balance due to its effect on extracellular fluid osmolality and volume. The addition of macronutrients such as carbohydrate and protein can promote maintenance of hydration by influencing absorption and distribution of ingested water, which in turn effects extracellular fluid osmolality and volume. Alcohol is commonly consumed in the postexercise period and may influence postexercise rehydration, as will the coingestion of food. Future research in this area should focus on providing information related to optimal rates of fluid ingestion, advisable solutions to ingest during different duration recovery periods, and confirmation of mechanistic explanations for the observations outlined. Copyright © 2017 the American Physiological Society.

42 CFR 424.350 - Replacement of checks that are lost, stolen, defaced, mutilated, destroyed, or paid on forged...

Code of Federal Regulations, 2010 CFR

2010-10-01

... CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM CONDITIONS FOR MEDICARE PAYMENT Replacement and Reclamation of Medicare Payments § 424.350... investigation and settlement of claims in connection with Treasury checks issued on behalf of CMS. (2) Action by...

Economic consequences of workplace injuries and illnesses: lost earnings and benefit adequacy.

PubMed

Boden, L I; Galizzi, M

1999-11-01

This is the first study based on individual data to estimate earnings lost from virtually all reported workplace injuries and illnesses in a state. We estimated lost earnings from workplace injuries and illnesses occurring in Wisconsin in 1989-90, using workers' compensation data and 6 years of unemployment insurance wage data. We used regression techniques to estimate losses relative to a comparison group. The average present value of losses projected 10 years past the observed period is over $8,000 per injury. Women lose a greater proportion of their preinjury earnings than do men. Replacement of after-tax projected losses averages 64% for men and 50% for women. Overall, workers with compensated injuries and illnesses experienced discounted pre-tax losses projected to total over $530,000,000 (1994 dollars), with about 60% of after-tax losses replaced by workers' compensation. Generally, groups losing over eight weeks' work received workers' compensation benefits covering less than 40% of their losses. Copyright 1999 Wiley-Liss, Inc.

Income Replacement and Reemployment Programs in Michigan and Neighboring States. W.E. Upjohn Institute Staff Working Paper.

ERIC Educational Resources Information Center

Woodbury, Stephen A.

Income replacement and reemployment programs in Michigan and its neighboring states were examined in the context of recent changes in federal policy regarding compensation and services for individuals who have lost their jobs or sustained job-related injuries. The analysis focused primarily on the following programs: (1) Unemployment Insurance…

Adaptive perch selection as a mechanism of adoption by a replacement Bald Eagle

Treesearch

Teryl G. Grubb; Larry A. Forbis; Marta McWhorter; David R. Sherman

1988-01-01

Replacement of lost mates within the same nesting season has been recorded in 26 raptor species (Newton 1979). Only three species (Cooper’s Hawk, Accipiter cooperii; Northern Goshawk, A. gentilis; and Peregrine Falcon, Falco peregrinus) have exhibited full adoption, i.e., incubation of eggs and/or rearing of...

Fluid consumption and sweating in National Football League and collegiate football players with different access to fluids during practice.

PubMed

Godek, Sandra Fowkes; Bartolozzi, Arthur R; Peduzzi, Chris; Heinerichs, Scott; Garvin, Eugene; Sugarman, Eric; Burkholder, Richard

2010-01-01

Considerable controversy regarding fluid replacement during exercise currently exists. To compare fluid turnover between National Football League (NFL) players who have constant fluid access and collegiate football players who replace fluids during water breaks in practices. Observational study. Respective preseason training camps of 1 National Collegiate Athletic Association Division II (DII) football team and 1 NFL football team. Both morning and afternoon practices for DII players were 2.25 hours in length, and NFL players practiced for 2.25 hours in the morning and 1 hour in the afternoon. Environmental conditions did not differ. Eight NFL players (4 linemen, 4 backs) and 8 physically matched DII players (4 linemen, 4 backs) participated. All players drank fluids only from their predetermined individual containers. The NFL players could consume both water and sports drinks, and the DII players could only consume water. We measured fluid consumption, sweat rate, total sweat loss, and percentage of sweat loss replaced. Sweat rate was calculated as change in mass adjusted for fluids consumed and urine produced. Mean sweat rate was not different between NFL (2.1 +/- 0.25 L/h) and DII (1.8 +/- 0.15 L/h) players (F(1,12) = 2, P = .18) but was different between linemen (2.3 +/- 0.2 L/h) and backs (1.6 +/- 0.2 L/h) (t(14) = 3.14, P = .007). We found no differences between NFL and DII players in terms of percentage of weight loss (t(7) = -0.03, P = .98) or rate of fluid consumption (t(7) = -0.76, P = .47). Daily sweat loss was greater in DII (8.0 +/- 2.0 L) than in NFL (6.4 +/- 2.1 L) players (t(7) = -3, P = .02), and fluid consumed was also greater in DII (5.0 +/- 1.5 L) than in NFL (4.0 +/- 1.1 L) players (t(7) = -2.8, P = .026). We found a correlation between sweat loss and fluids consumed (r = 0.79, P < .001). During preseason practices, the DII players drinking water at water breaks replaced the same volume of fluid (66% of weight lost) as NFL players with constant access to both water and sports drinks.

Does Replacing Sodium Excreted in Sweat Attenuate the Health Benefits of Physical Activity?

PubMed

Turner, Martin J; Avolio, Alberto P

2016-08-01

International guidelines suggest limiting sodium intake to 86-100 mmol/day, but average intake exceeds 150 mmol/day. Participants in physical activities are, however, advised to increase sodium intake before, during and after exercise to ensure euhydration, replace sodium lost in sweat, speed rehydration and maintain performance. A similar range of health benefits is attributable to exercise and to reduction in sodium intake, including reductions in blood pressure (BP) and the increase of BP with age, reduced risk of stroke and other cardiovascular diseases, and reduced risk of osteoporosis and dementia. Sweat typically contains 40-60 mmol/L of sodium, leading to approximately 20-90 mmol of sodium lost in one exercise session with sweat rates of 0.5-1.5 L/h. Reductions in sodium intake of 20-90 mmol/day have been associated with substantial health benefits. Homeostatic systems reduce sweat sodium as low as 3-10 mmol/L to prevent excessive sodium loss. "Salty sweaters" may be individuals with high sodium intake who perpetuate their "salty sweat" condition by continual replacement of sodium excreted in sweat. Studies of prolonged high intensity exercise in hot environments suggest that sodium supplementation is not necessary to prevent hyponatremia during exercise lasting up to 6 hr. We examine the novel hypothesis that sodium excreted in sweat during physical activity offsets a significant fraction of excess dietary sodium, and hence may contribute part of the health benefits of exercise. Replacing sodium lost in sweat during exercise may improve physical performance, but may attenuate the long-term health benefits of exercise.

50 CFR 23.52 - What are the requirements for replacing a lost, damaged, stolen, or accidentally destroyed CITES...

Code of Federal Regulations, 2010 CFR

2010-10-01

... information you need to provide (more than one circumstance may apply to you): If Then (i) The shipment has.... When applying for a U.S. replacement document, you must provide sufficient information for us to find... issued for a shipment that has already occurred does not require validation. (f) Validation. For an...

Diurnal trends in methylmercury concentration in a wetland adjacent to Great Salt Lake, Utah, USA

USGS Publications Warehouse

Naftz, D.L.; Cederberg, J.R.; Krabbenhoft, D.P.; Beisner, K.R.; Whitehead, J.; Gardberg, J.

2011-01-01

A 24-h field experiment was conducted during July 2008 at a wetland on the eastern shore of Great Salt Lake (GSL) to assess the diurnal cycling of methylmercury (MeHg). Dissolved (<0.45??m) MeHg showed a strong diurnal variation with consistently decreasing concentrations during daylight periods and increasing concentrations during non-daylight periods. The proportion of MeHg relative to total Hg in the water column consistently decreased with increasing sunlight duration, indicative of photodegradation. During the field experiment, measured MeHg photodegradation rates ranged from 0.02 to 0.06ngL-1h-1. Convective overturn of the water column driven by nighttime cooling of the water surface was hypothesized as the likely mechanism to replace the MeHg in the water column lost via photodegradation processes. A hydrodynamic model of the wetland successfully simulated convective overturn of the water column during the field experiment. Study results indicate that daytime monitoring of selected wetlands surrounding GSL may significantly underestimate the MeHg content in the water column. Wetland managers should consider practices that maximize the photodegradation of MeHg during daylight periods. ?? 2011.

Behavioral rehabilitation of the eye closure reflex in senescent rats using a real-time biosignal acquisition system.

PubMed

Prueckl, R; Taub, A H; Herreros, I; Hogri, R; Magal, A; Bamford, S A; Giovannucci, A; Almog, R Ofek; Shacham-Diamand, Y; Verschure, P F M J; Mintz, M; Scharinger, J; Silmon, A; Guger, C

2011-01-01

In this paper the replacement of a lost learning function of rats through a computer-based real-time recording and feedback system is shown. In an experiment two recording electrodes and one stimulation electrode were implanted in an anesthetized rat. During a classical-conditioning paradigm, which includes tone and airpuff stimulation, biosignals were recorded and the stimulation events detected. A computational model of the cerebellum acquired the association between the stimuli and gave feedback to the brain of the rat using deep brain stimulation in order to close the eyelid of the rat. The study shows that replacement of a lost brain function using a direct bidirectional interface to the brain is realizable and can inspire future research for brain rehabilitation.

Saline water in the Little Arkansas River Basin area, south-central Kansas

USGS Publications Warehouse

Leonard, Robert B.; Kleinschmidt, Melvin K.

1976-01-01

Ground water in unconsolidated deposits of Pleistocene age in part of the Little Arkansas River basin has been polluted by the influx of saline water. The source of the saline water generally is oil-field brine that leaked from disposal ponds on the land surface. Locally, pollution by saline water also has been caused by upwelling of oil-field brine injected under pressure into the "lost-circulation zone" of the Lower Permian Wellington Formation and, possibly, by leakage of brine from corroded or improperly cased disposal wells. Anomalously high concentrations of chloride ion in some reaches of the Little Arkansas River probably can be attributed to pollution by municipal wastes rather than from inflow of saline ground water. Hydraulic connection exists between the "lost-circulation zone" and unconsolidated deposits, as evidenced by the continuing development of sinkholes, by the continuing discharge of saline water through springs and seeps along the Arkansas River south of the Little Arkansas River basin and by changes in the chloride concentration in water pumped from wells in the "lost-circulation zone." The hydraulic head in the "lost-circulation zone" is below the base of the unconsolidated deposits, and much below the potentiometric surface of the aquifer in those deposits. Any movement of water, therefore, would be downward from the "fresh-water" aquifer to the saline "lost-circulation zone."

Vomiting and Diarrhea

MedlinePlus

... Kids and Teens Pregnancy and Childbirth Women Men Seniors Your Health Resources Healthcare Management End-of-Life ... can irritate your child’s stomach. For adults and seniors: To replace the fluids lost from vomiting and ...

From lin-benzoguanines to lin-benzohypoxanthines as ligands for Zymomonas mobilis tRNA-guanine transglycosylase: replacement of protein-ligand hydrogen bonding by importing water clusters.

PubMed

Barandun, Luzi Jakob; Immekus, Florian; Kohler, Philipp C; Tonazzi, Sandro; Wagner, Björn; Wendelspiess, Severin; Ritschel, Tina; Heine, Andreas; Kansy, Manfred; Klebe, Gerhard; Diederich, François

2012-07-23

The foodborne illness shigellosis is caused by Shigella bacteria that secrete the highly cytotoxic Shiga toxin, which is also formed by the closely related enterohemorrhagic Escherichia coli (EHEC). It has been shown that tRNA-guanine transglycosylase (TGT) is essential for the pathogenicity of Shigella flexneri. Herein, the molecular recognition properties of a guanine binding pocket in Zymomonas mobilis TGT are investigated with a series of lin-benzohypoxanthine- and lin-benzoguanine-based inhibitors that bear substituents to occupy either the ribose-33 or the ribose-34 pocket. The three inhibitor scaffolds differ by the substituent at C(6) being H, NH(2), or NH-alkyl. These differences lead to major changes in the inhibition constants, pK(a) values, and binding modes. Compared to the lin-benzoguanines, with an exocyclic NH(2) at C(6), the lin-benzohypoxanthines without an exocyclic NH(2) group have a weaker affinity as several ionic protein-ligand hydrogen bonds are lost. X-ray cocrystal structure analysis reveals that a new water cluster is imported into the space vacated by the lacking NH(2) group and by a conformational shift of the side chain of catalytic Asp102. In the presence of an N-alkyl group at C(6) in lin-benzoguanine ligands, this water cluster is largely maintained but replacement of one of the water molecules in the cluster leads to a substantial loss in binding affinity. This study provides new insight into the role of water clusters at enzyme active sites and their challenging substitution by ligand parts, a topic of general interest in contemporary structure-based drug design. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Biological tooth replacement

PubMed Central

Sartaj, Rachel; Sharpe, Paul

2006-01-01

Teeth develop from a series of reciprocal interactions that take place between epithelium and mesenchyme during development of the mouth that begin early in mammalian embryogenesis. The molecular control of key processes in tooth development such as initiation, morphogenesis and cytodifferentiation are being increasingly better understood, to the point where this information can be used as the basis for approaches to produce biological replacement teeth (BioTeeth). This review outlines the current approaches, ideas and progress towards the production of BioTeeth that could form an alternative method for replacing lost or damaged teeth. PMID:17005022

Autosomal Dominant Polycystic Kidney Disease

MedlinePlus

... replacement therapies—hemodialysis and kidney transplantation, developed through fundamental NIH research in the 1960s—were increasingly available ... possible to restore lost kidney function. More aggressive management of diabetes and high blood pressure, as well ...

33 CFR 173.85 - Fees levied by the Coast Guard.

Code of Federal Regulations, 2012 CFR

2012-07-01

... number and two validation stickers—$24. (2) Renewed certificate of number and two validation stickers—$16. (3) Duplicate certificate of number—$9. (4) Replacement of lost or destroyed validation stickers—$9...

33 CFR 173.85 - Fees levied by the Coast Guard.

Code of Federal Regulations, 2014 CFR

2014-07-01

... number and two validation stickers—$24. (2) Renewed certificate of number and two validation stickers—$16. (3) Duplicate certificate of number—$9. (4) Replacement of lost or destroyed validation stickers—$9...

33 CFR 173.85 - Fees levied by the Coast Guard.

Code of Federal Regulations, 2011 CFR

2011-07-01

... number and two validation stickers—$24. (2) Renewed certificate of number and two validation stickers—$16. (3) Duplicate certificate of number—$9. (4) Replacement of lost or destroyed validation stickers—$9...

33 CFR 173.85 - Fees levied by the Coast Guard.

Code of Federal Regulations, 2013 CFR

2013-07-01

... number and two validation stickers—$24. (2) Renewed certificate of number and two validation stickers—$16. (3) Duplicate certificate of number—$9. (4) Replacement of lost or destroyed validation stickers—$9...

Compensatory Mitigation for Losses of Aquatic Resources; Final Rule

EPA Pesticide Factsheets

These regulations are designed to improve the effectiveness of compensatory mitigation to replace lost aquatic resource functions and area, and increase the efficiency and predictability of the mitigation project review process.

The validity of survivorship analysis in total joint arthroplasty.

PubMed

Dorey, F; Amstutz, H C

1989-04-01

The use of survivorship analysis requires an assumption that patients who are lost to follow-up are no more or less likely to be at risk of failure of an operation or a procedure than are patients who are still being followed. This is a major assumption in long-term orthopaedic studies, in which a high percentage of patients are usually lost to follow-up. We compared the survivorship curve for the first 100 Tharies replacements done at our institution (which were completed by September 1977), using data that were collected in the standard way up to 1985, through a letter requesting a follow-up visit, with the curve for the same patients that was based on almost complete follow-up data that were gathered by telephone from 1985 on. The similarity of the two curves suggested that the assumptions that are necessary for the validity of survivorship analysis are reasonable, even in the orthopaedic setting, in which many patients are lost to follow-up. The usefulness of the survivorship curve for prediction was also evaluated by comparing the curve based on the first forty-six of the 100 Tharies replacements (before 1977) with the curve based on the last fifty-four such operations (from January 1977 to September 1977). The results of these two comparisons suggest that survivorship analysis is a valid technique to use in the long-term evaluation of patients who have had a joint replacement.

Feed intake, forestomach fluid volume, dilution rate and mean retention of fluid in the forestomach during water deprivation and rehydration in camels (Camelus sp.).

PubMed

von Engelhardt, W; Haarmeyer, P; Lechner-Doll, M

2006-04-01

Camels were deprived of water for 11 days. Before and during water deprivation and during rehydration changes in body weight, feed and water intake were measured. Using the liquid marker Cr-EDTA forestomach fluid volume, mean fluid retention and fluid dilution in the forestomach were estimated. At the eleventh day of water deprivation hay intake had decreased to only 9.6% of controls, dilution rates had decreased to 31%, mean retention time of fluid in the forestomach had increased to 189%. At the end of dehydration flow of saliva of 2 l/h mainly contributed to the still rather high dilution rates. Thereby buffering capacity and flow of fluid into the forestomach for microbial digestion as well as the outflow from the forestomach were maintained. At the beginning of rehydration camels drank 97 l within a few minutes, and animals thereby replaced all the water lost. Following this first huge water intake water is rapidly absorbed from the forestomach, and forestomach volume decreased again to dehydration values. At the third day of rehydration control values were reached again. Although feed intake decreased dramatically during water deprivation, functions of the forestomach can be maintained sufficiently mainly due to saliva inflow. This explains the mostly rapid recovery of camels when water is available again.

Effects of fasting and refeeding on body composition of captive gray wolves (Canis lupus)

USGS Publications Warehouse

Kreeger, T.J.; DelGiudice, G.D.; Mech, L.D.

1997-01-01

We examined the effects of fasting and refeeding on body composition in 9 captive adult gray wolves, Canis lupus (6 males, 3 females), during May-June 1995. Body composition was estimated by the technique of tritiated water dilution. Wolves were immobilized and weighed, baseline blood samples were taken, tritiated water was injected, and additional blood samples were taken before fasting, after 10 d of fasting, and again after 2 d of refeeding. Male wolves lost 8% (P = 0.0001) and females lost 7% body mass (P = 0.01) during the 10 d. Males lost 54% of this mass in water, 28% in fat, and 18% in protein/ash; females lost 58% in water, 20% in fat, and 22% in protein/ash. Upon refeeding, male wolves consumed an average of 6.8 kg (15.3% body mass) of deer meat per day and females consumed 6.4 kg (18.7% body mass). All wolves regained their initial mass. Males regained 24% of this mass in water, 70% in fat, and 6% in protein/ash; females regained 35% in water, 51% in fat, and 14% in protein/ash. This study provided evidence that after prolonged fasting, captive wolves could quickly and efficiently regain lost body mass after refeeding.

Environmental Assessment: PL 84-99 Levee Rahabilitation Program Lower Platte South Natural Resource District Salt Creek, Lincoln, Lancaster County, Nebraska

DTIC Science & Technology

2015-03-01

lost bank material with compacted, non-dispersive clay and riprap; constructing landward piggy-back levees at discrete locations if space is available...consist of approximately seven miles of levees. The levees have 3:1 side slopes that are made up of clay soil, with a two-foot minimum freeboard. The...reshaping the levee and replacing lost bank material with compacted, non-dispersive clay and riprap or building a landside piggy back levee if space is

International Space Station (ISS)

NASA Image and Video Library

2000-09-01

The Environmental Control and Life Support System (ECLSS) Group of the Flight Projects Directorate at the Marshall Space Flight Center (MSFC) in Huntsville, Alabama, is responsible for designing and building the life support systems that will provide the crew of the International Space Station (ISS) a comfortable environment in which to live and work. This is a close-up view of ECLSS Oxygen Generation System (OGS) rack. The ECLSS Group at the MSFC oversees the development of the OGS, which produces oxygen for breathing air for the crew and laboratory animals, as well as for replacing oxygen lost due to experiment use, airlock depressurization, module leakage, and carbon dioxide venting. The OGS consists primarily of the Oxygen Generator Assembly (OGA), provided by the prime contractor, the Hamilton Sundstrand Space Systems, International (HSSSI) in Windsor Locks, Cornecticut and a Power Supply Module (PSM), supplied by the MSFC. The OGA is comprised of a cell stack that electrolyzes (breaks apart the hydrogen and oxygen molecules) some of the clean water provided by the Water Recovery System and the separators that remove the gases from water after electrolysis. The PSM provides the high power to the OGA needed to electrolyze the water.

Geographic information system datasets of regolith-thickness data, regolith-thickness contours, raster-based regolith thickness, and aquifer-test and specific-capacity data for the Lost Creek Designated Ground Water Basin, Weld, Adams, and Arapahoe Counties, Colorado

USGS Publications Warehouse

Arnold, L. Rick

2010-01-01

These datasets were compiled in support of U.S. Geological Survey Scientific-Investigations Report 2010-5082-Hydrogeology and Steady-State Numerical Simulation of Groundwater Flow in the Lost Creek Designated Ground Water Basin, Weld, Adams, and Arapahoe Counties, Colorado. The datasets were developed by the U.S. Geological Survey in cooperation with the Lost Creek Ground Water Management District and the Colorado Geological Survey. The four datasets are described as follows and methods used to develop the datasets are further described in Scientific-Investigations Report 2010-5082: (1) ds507_regolith_data: This point dataset contains geologic information concerning regolith (unconsolidated sediment) thickness and top-of-bedrock altitude at selected well and test-hole locations in and near the Lost Creek Designated Ground Water Basin, Weld, Adams, and Arapahoe Counties, Colorado. Data were compiled from published reports, consultant reports, and from lithologic logs of wells and test holes on file with the U.S. Geological Survey Colorado Water Science Center and the Colorado Division of Water Resources. (2) ds507_regthick_contours: This dataset consists of contours showing generalized lines of equal regolith thickness overlying bedrock in the Lost Creek Designated Ground Water Basin, Weld, Adams, and Arapahoe Counties, Colorado. Regolith thickness was contoured manually on the basis of information provided in the dataset ds507_regolith_data. (3) ds507_regthick_grid: This dataset consists of raster-based generalized thickness of regolith overlying bedrock in the Lost Creek Designated Ground Water Basin, Weld, Adams, and Arapahoe Counties, Colorado. Regolith thickness in this dataset was derived from contours presented in the dataset ds507_regthick_contours. (4) ds507_welltest_data: This point dataset contains estimates of aquifer transmissivity and hydraulic conductivity at selected well locations in the Lost Creek Designated Ground Water Basin, Weld, Adams, and Arapahoe Counties, Colorado. This dataset also contains hydrologic information used to estimate transmissivity from specific capacity at selected well locations. Data were compiled from published reports, consultant reports, and from well-test records on file with the U.S. Geological Survey Colorado Water Science Center and the Colorado Division of Water Resources.

20 CFR 416.1103 - What is not income?

Code of Federal Regulations, 2010 CFR

2010-04-01

... a lawn service to mow your grass, the payment is not income to you because the mowing cannot be used.... (h) Replacement of income you have already received. If income is lost, destroyed, or stolen and you...

Land-use change and costs to rural households: a case study in groundwater nitrate contamination

NASA Astrophysics Data System (ADS)

Keeler, Bonnie L.; Polasky, Stephen

2014-07-01

Loss of grassland from conversion to agriculture threatens water quality and other valuable ecosystem services. Here we estimate how land-use change affects the probability of groundwater contamination by nitrate in private drinking water wells. We find that conversion of grassland to agriculture from 2007 to 2012 in Southeastern Minnesota is expected to increase the future number of wells exceeding 10 ppm nitrate-nitrogen by 45% (from 888 to 1292 wells). We link outputs of the groundwater well contamination model to cost estimates for well remediation, well replacement, and avoidance behaviors to estimate the potential economic value lost due to nitrate contamination from observed land-use change. We estimate 0.7-12 million in costs (present values over a 20 year horizon) to address the increased risk of nitrate contamination of private wells. Our study demonstrates how biophysical models and economic valuation can be integrated to estimate the welfare consequences of land-use change.

Parents' and Coaches' Guide to Dehydration and Other Heat Illnesses in Children

MedlinePlus

... illnesses can be prevented and successfully treated. Children sweat less than adults. This makes it harder for ... they do not replace body fluids lost by sweating. Being even a little dehydrated can make a ...

20 CFR 416.1232 - Replacement of lost, damaged, or stolen excluded resources.

Code of Federal Regulations, 2010 CFR

2010-04-01

.... Exception: For victims of Hurricane Andrew only, the extension period for good cause may be extended for up... additional extension under the Hurricane Andrew provision) may be extended for a reasonable period up to an...

20 CFR 416.1232 - Replacement of lost, damaged, or stolen excluded resources.

Code of Federal Regulations, 2014 CFR

2014-04-01

.... Exception: For victims of Hurricane Andrew only, the extension period for good cause may be extended for up... additional extension under the Hurricane Andrew provision) may be extended for a reasonable period up to an...

20 CFR 416.1232 - Replacement of lost, damaged, or stolen excluded resources.

Code of Federal Regulations, 2013 CFR

2013-04-01

.... Exception: For victims of Hurricane Andrew only, the extension period for good cause may be extended for up... additional extension under the Hurricane Andrew provision) may be extended for a reasonable period up to an...

20 CFR 416.1232 - Replacement of lost, damaged, or stolen excluded resources.

Code of Federal Regulations, 2011 CFR

2011-04-01

.... Exception: For victims of Hurricane Andrew only, the extension period for good cause may be extended for up... additional extension under the Hurricane Andrew provision) may be extended for a reasonable period up to an...

20 CFR 416.1232 - Replacement of lost, damaged, or stolen excluded resources.

Code of Federal Regulations, 2012 CFR

2012-04-01

.... Exception: For victims of Hurricane Andrew only, the extension period for good cause may be extended for up... additional extension under the Hurricane Andrew provision) may be extended for a reasonable period up to an...

Different polyamine pathways from bacteria have replaced eukaryotic spermidine biosynthesis in ciliates Tetrahymena thermophila and Paramecium tetaurelia.

PubMed

Li, Bin; Kim, Sok Ho; Zhang, Yang; Hanfrey, Colin C; Elliott, Katherine A; Ealick, Steven E; Michael, Anthony J

2015-09-01

The polyamine spermidine is absolutely required for growth and cell proliferation in eukaryotes, due to its role in post-translational modification of essential translation elongation factor eIF5A, mediated by deoxyhypusine synthase. We have found that free-living ciliates Tetrahymena and Paramecium lost the eukaryotic genes encoding spermidine biosynthesis: S-adenosylmethionine decarboxylase (AdoMetDC) and spermidine synthase (SpdSyn). In Tetrahymena, they were replaced by a gene encoding a fusion protein of bacterial AdoMetDC and SpdSyn, present as three copies. In Paramecium, a bacterial homospermidine synthase replaced the eukaryotic genes. Individual AdoMetDC-SpdSyn fusion protein paralogues from Tetrahymena exhibit undetectable AdoMetDC activity; however, when two paralogous fusion proteins are mixed, AdoMetDC activity is restored and spermidine is synthesized. Structural modelling indicates a functional active site is reconstituted by sharing critical residues from two defective protomers across the heteromer interface. Paramecium was found to accumulate homospermidine, suggesting it replaces spermidine for growth. To test this concept, a budding yeast spermidine auxotrophic strain was found to grow almost normally with homospermidine instead of spermidine. Biosynthesis of spermidine analogue aminopropylcadaverine, but not exogenously provided norspermidine, correlated with some growth. Finally, we found that diverse single-celled eukaryotic parasites and multicellular metazoan Schistosoma worms have lost the spermidine biosynthetic pathway but retain deoxyhypusine synthase. © 2015 John Wiley & Sons Ltd.

Hydrologic Change during the Colonial Era of the United States: Beavers and the Energy Cost of Impoundments (Invited)

NASA Astrophysics Data System (ADS)

Green, M. B.; Bain, D. J.; Arrigo, J. S.; Duncan, J. M.; Kumar, S.; Parolari, A.; Salant, N.; Vorosmarty, C. J.; Aloysius, N. R.; Bray, E. N.; Ruffing, C. M.; Witherell, B. B.

2009-12-01

Europeans colonized North America in the early 17th century with intentions ranging between long-term inhabitation and quick extraction of resources for economic gain in Europe. Whatever the intentions, the colonists relied on the landscape for resources resulting in dramatic change to the forest and fur-bearing mammal population. We demonstrate that initial exploitation of North American forest and furs caused a substantial decrease in mean water residence time (τ) between 1600 and 1800 A.D. That loss, which regionally changed from 51 to 41 days, contrasts with conventional wisdom that humans tend to diminish variability in water resources by increasing storage capacity and thus increasing τ. The loss of τ resulted from over-hunted beaver for the hat market in Europe. Analysis suggests that colonial era demographics and economics did not allow human resource allocation to impoundment construction on a level matching the historic beaver effort. However, the τ appears to have regionally increased during the 19th century, suggesting that humans eventually began replacing the water storage lost with the beaver. The analysis highlights the energy cost of impounding water, which is likely to continue to be an important factor given the increasing need for stable water resources and finite energy resources.

42 CFR 424.350 - Replacement of checks that are lost, stolen, defaced, mutilated, destroyed, or paid on forged...

Code of Federal Regulations, 2011 CFR

2011-10-01

... CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE... investigation and settlement of claims in connection with Treasury checks issued on behalf of CMS. (2) Action by...

Survival of dental implants placed in sites of previously failed implants.

PubMed

Chrcanovic, Bruno R; Kisch, Jenö; Albrektsson, Tomas; Wennerberg, Ann

2017-11-01

To assess the survival of dental implants placed in sites of previously failed implants and to explore the possible factors that might affect the outcome of this reimplantation procedure. Patients that had failed dental implants, which were replaced with the same implant type at the same site, were included. Descriptive statistics were used to describe the patients and implants; survival analysis was also performed. The effect of systemic, environmental, and local factors on the survival of the reoperated implants was evaluated. 175 of 10,096 implants in 98 patients were replaced by another implant at the same location (159, 14, and 2 implants at second, third, and fourth surgeries, respectively). Newly replaced implants were generally of similar diameter but of shorter length compared to the previously placed fixtures. A statistically significant greater percentage of lost implants were placed in sites with low bone quantity. There was a statistically significant difference (P = 0.032) in the survival rates between implants that were inserted for the first time (94%) and implants that replaced the ones lost (73%). There was a statistically higher failure rate of the reoperated implants for patients taking antidepressants and antithrombotic agents. Dental implants replacing failed implants had lower survival rates than the rates reported for the previous attempts of implant placement. It is suggested that a site-specific negative effect may possibly be associated with this phenomenon, as well as the intake of antidepressants and antithrombotic agents. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Aggregation protects flexible-shelled reptile eggs from severe hydric stress.

PubMed

Marco, Adolfo; Díaz-Paniagua, Carmen

2008-03-01

Many reptiles lay eggs with flexible shells that can progressively lose water until lethal dehydration under dry soil conditions. The number of eggs that develop together may influence the water exchange in the nest. We hypothesise that egg aggregation could reduce water lost under dry conditions. We exposed aggregated and isolated eggs to severe hydric stress followed by a period of rehydration. Hydric stress caused a general loss of water in common chameleon eggs. Initial egg mass did not affect survival but eggs that had lost more water had higher mortality and produced smaller hatchlings. Mass loss was higher and even lethal for isolated Chamaeleo chameleon eggs. However, aggregated eggs lost less water and most survived this period. After hydric stress, all surviving eggs gained mass via water absorption, and aggregation negatively affected water uptake. Isolated eggs hatched at smaller sizes than aggregated eggs. Aggregation also favoured hatching synchrony. Large clutches may favour hatching success of terrestrial flexible-shelled eggs incubated under severe drought conditions.

Fluid Consumption and Sweating in National Football League and Collegiate Football Players With Different Access to Fluids During Practice

PubMed Central

Godek, Sandra Fowkes; Bartolozzi, Arthur R.; Peduzzi, Chris; Heinerichs, Scott; Garvin, Eugene; Sugarman, Eric; Burkholder, Richard

2010-01-01

Abstract Context: Considerable controversy regarding fluid replacement during exercise currently exists. Objective: To compare fluid turnover between National Football League (NFL) players who have constant fluid access and collegiate football players who replace fluids during water breaks in practices. Design: Observational study. Setting: Respective preseason training camps of 1 National Collegiate Athletic Association Division II (DII) football team and 1 NFL football team. Both morning and afternoon practices for DII players were 2.25 hours in length, and NFL players practiced for 2.25 hours in the morning and 1 hour in the afternoon. Environmental conditions did not differ. Patients or Other Participants: Eight NFL players (4 linemen, 4 backs) and 8 physically matched DII players (4 linemen, 4 backs) participated. Intervention(s): All players drank fluids only from their predetermined individual containers. The NFL players could consume both water and sports drinks, and the DII players could only consume water. Main Outcome Measure(s): We measured fluid consumption, sweat rate, total sweat loss, and percentage of sweat loss replaced. Sweat rate was calculated as change in mass adjusted for fluids consumed and urine produced. Results: Mean sweat rate was not different between NFL (2.1 ± 0.25 L/h) and DII (1.8 ± 0.15 L/h) players (F1,12  =  2, P  =  .18) but was different between linemen (2.3 ± 0.2 L/h) and backs (1.6 ± 0.2 L/h) (t14  =  3.14, P  =  .007). We found no differences between NFL and DII players in terms of percentage of weight loss (t7  =  −0.03, P  =  .98) or rate of fluid consumption (t7  =  −0.76, P  =  .47). Daily sweat loss was greater in DII (8.0 ± 2.0 L) than in NFL (6.4 ± 2.1 L) players (t7  =  −3, P  =  .02), and fluid consumed was also greater in DII (5.0 ± 1.5 L) than in NFL (4.0 ± 1.1 L) players (t7  =  −2.8, P  =  .026). We found a correlation between sweat loss and fluids consumed (r  =  0.79, P < .001). Conclusions: During preseason practices, the DII players drinking water at water breaks replaced the same volume of fluid (66% of weight lost) as NFL players with constant access to both water and sports drinks. PMID:20210616

Meal Replacement Beverage Twice a Day in Overweight and Obese Adults (MDRC2012-001)

PubMed Central

Frestedt, Joy L; Young, Lindsay R; Bell, Margie

2012-01-01

This open label, single arm, prospective, interventional, weight loss trial evaluated a meal replacement beverage (Right Size® Smoothie) used to replace breakfast and lunch each day for 12 weeks (7 clinic visits) as part of a calorie-restricted diet in overweight and obese adults. A total of 155 individuals were screened, 55 enrolled and 28 completed this 12 week study. Subjects were obese (mean weight: 206 pounds and BMI: 32.7 kg/m2) and the mean age was 40 years including 42 (76.4%) female and 13 (23.6%) male volunteers. The modified Intent to Treat and Completer groups lost an average of 10.6 and 13.8 pounds and reduced their average BMI by 1.7 and 2.2 kg/m2 respectively during this 12 week trial. The Per Protocol group lost 15.2 pounds and 2.4 kg/m2 and the Optimal Weight Loss group lost 18.5 pounds and 2.9 kg/m2. Using the Satiety Labeled Intensity Magnitude scale (SLIM) questionnaire, subjects reported feeling relatively hungry before they consumed the beverage, then feeling relatively full 15 minutes following the beverage with the sensation of some fullness lasting more than 2 hours and then feeling relatively hungry again at 3 hours after consuming the beverage. Study subjects reported significant improvements in physical functioning, general health, vitality and mental health as well as increased cognitive restraint of eating, reduced disinhibition and reduced hunger during the trial. The study beverages were well tolerated and no Serious Adverse Events (SAE) reported. This study suggests the study beverage aids in weight loss by helping to curb hunger during a reduced calorie diet program. PMID:23236298

PERSPECTIVE: Electrical activity enhances neuronal survival and regeneration

NASA Astrophysics Data System (ADS)

Corredor, Raul G.; Goldberg, Jeffrey L.

2009-10-01

The failure of regeneration in the central nervous system (CNS) remains an enormous scientific and clinical challenge. After injury or in degenerative diseases, neurons in the adult mammalian CNS fail to regrow their axons and reconnect with their normal targets, and furthermore the neurons frequently die and are not normally replaced. While significant progress has been made in understanding the molecular basis for this lack of regenerative ability, a second approach has gained momentum: replacing lost neurons or lost connections with artificial electrical circuits that interface with the nervous system. In the visual system, gene therapy-based 'optogenetics' prostheses represent a competing technology. Now, the two approaches are converging, as recent data suggest that electrical activity itself, via the molecular signaling pathways such activity stimulates, is sufficient to induce neuronal survival and regeneration, particularly in retinal ganglion cells. Here, we review these data, discuss the effects of electrical activity on neurons' molecular signaling pathways and propose specific mechanisms by which exogenous electrical activity may be acting to enhance survival and regeneration.

Treating hearing disorders with cell and gene therapy

NASA Astrophysics Data System (ADS)

Gillespie, Lisa N.; Richardson, Rachael T.; Nayagam, Bryony A.; Wise, Andrew K.

2014-12-01

Hearing loss is an increasing problem for a substantial number of people and, with an aging population, the incidence and severity of hearing loss will become more significant over time. There are very few therapies currently available to treat hearing loss, and so the development of new therapeutic strategies for hearing impaired individuals is of paramount importance to address this unmet clinical need. Most forms of hearing loss are progressive in nature and therefore an opportunity exists to develop novel therapeutic approaches to slow or halt hearing loss progression, or even repair or replace lost hearing function. Numerous emerging technologies have potential as therapeutic options. This paper details the potential of cell- and gene-based therapies to provide therapeutic agents to protect sensory and neural cells from various insults known to cause hearing loss; explores the potential of replacing lost sensory and nerve cells using gene and stem cell therapy; and describes the considerations for clinical translation and the challenges that need to be overcome.

Energy density of anchovy Engraulis encrasicolus in the Bay of Biscay.

PubMed

Dubreuil, J; Petitgas, P

2009-02-01

The energy density (E(D)) of anchovy Engraulis encrasicolus in the Bay of Biscay was determined by direct calorimetry and its evolution with size, age and season was investigated. The water content and energy density varied seasonally following opposite trends. The E(D) g(-1) of wet mass (M(W)) was highest at the end of the feeding season (autumn: c. 8 kJ g(-1)M(W)) and lowest in late winter (c. 6 kJ g(-1)M(W)). In winter, the fish lost mass, which was partially replaced by water, and the energy density decreased. These variations in water content and organic matter content may have implications on the buoyancy of the fish. The water content was the major driver of the energy density variations for a M(W) basis. A significant linear relationship was established between E(D) g(-1) (y) and the per cent dry mass (M(D); x): y =-4.937 + 0.411x. In the light of the current literature, this relationship seemed to be not only species specific but also ecosystem specific. Calibration and validation of fish bioenergetics models require energy content measurements on fish samples collected at sea. The present study provides a first reference for the energetics of E. encrasicolus in the Bay of Biscay.

Preoperational Subsurface Conditions at the Idaho Nuclear Technology and Engineering Center Service Waste Disposal Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ansley, Shannon Leigh

2002-02-01

The Idaho Nuclear Technology and Engineering Center (INTEC) Service Wastewater Discharge Facility replaces the existing percolation ponds as a disposal facility for the INTEC Service Waste Stream. A preferred alternative for helping decrease water content in the subsurface near INTEC, closure of the existing ponds is required by the INTEC Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) Record of Decision (ROD) for Waste Area Group 3 Operable Unit 3-13 (DOE-ID 1999a). By August 2002, the replacement facility was constructed approximately 2 miles southwest of INTEC, near the Big Lost River channel. Because groundwater beneath the Idaho National Engineering andmore » Environmental Laboratory (INEEL) is protected under Federal and State of Idaho regulations from degradation due to INEEL activities, preoperational data required by U.S. Department of Energy (DOE) Order 5400.1 were collected. These data include preexisting physical, chemical, and biological conditions that could be affected by the discharge; background levels of radioactive and chemical components; pertinent environmental and ecological parameters; and potential pathways for human exposure or environmental impact. This document presents specific data collected in support of DOE Order 5400.1, including: four quarters of groundwater sampling and analysis of chemical and radiological parameters; general facility description; site specific geology, stratigraphy, soils, and hydrology; perched water discussions; and general regulatory requirements. However, in order to avoid duplication of previous information, the reader is directed to other referenced publications for more detailed information. Documents that are not readily available are compiled in this publication as appendices. These documents include well and borehole completion reports, a perched water evaluation letter report, the draft INEEL Wellhead Protection Program Plan, and the Environmental Checklist.« less

Removal of distal protein–water hydrogen bonds in a plant epoxide hydrolase increases catalytic turnover but decreases thermostability

PubMed Central

Thomaeus, Ann; Naworyta, Agata; Mowbray, Sherry L.; Widersten, Mikael

2008-01-01

A putative proton wire in potato soluble epoxide hydrolase 1, StEH1, was identified and investigated by means of site-directed mutagenesis, steady-state kinetic measurements, temperature inactivation studies, and X-ray crystallography. The chain of hydrogen bonds includes five water molecules coordinated through backbone carbonyl oxygens of Pro186, Leu266, His269, and the His153 imidazole. The hydroxyl of Tyr149 is also an integrated component of the chain, which leads to the hydroxyl of Tyr154. Available data suggest that Tyr154 functions as a final proton donor to the anionic alkylenzyme intermediate formed during catalysis. To investigate the role of the putative proton wire, mutants Y149F, H153F, and Y149F/H153F were constructed and purified. The structure of the Y149F mutant was solved by molecular replacement and refined to 2.0 Å resolution. Comparison with the structure of wild-type StEH1 revealed only subtle structural differences. The hydroxyl group lost as a result of the mutation was replaced by a water molecule, thus maintaining a functioning hydrogen bond network in the proton wire. All mutants showed decreased catalytic efficiencies with the R,R-enantiomer of trans-stilbene oxide, whereas with the S,S-enantiomer, k cat/K M was similar or slightly increased compared with the wild-type reactions. k cat for the Y149F mutant with either TSO enantiomer was increased; thus the lowered enzyme efficiencies were due to increases in K M. Thermal inactivation studies revealed that the mutated enzymes were more sensitive to elevated temperatures than the wild-type enzyme. Hence, structural alterations affecting the hydrogen bond chain caused increases in k cat but lowered thermostability. PMID:18515642

Removal of distal protein-water hydrogen bonds in a plant epoxide hydrolase increases catalytic turnover but decreases thermostability.

PubMed

Thomaeus, Ann; Naworyta, Agata; Mowbray, Sherry L; Widersten, Mikael

2008-07-01

A putative proton wire in potato soluble epoxide hydrolase 1, StEH1, was identified and investigated by means of site-directed mutagenesis, steady-state kinetic measurements, temperature inactivation studies, and X-ray crystallography. The chain of hydrogen bonds includes five water molecules coordinated through backbone carbonyl oxygens of Pro(186), Leu(266), His(269), and the His(153) imidazole. The hydroxyl of Tyr(149) is also an integrated component of the chain, which leads to the hydroxyl of Tyr(154). Available data suggest that Tyr(154) functions as a final proton donor to the anionic alkylenzyme intermediate formed during catalysis. To investigate the role of the putative proton wire, mutants Y149F, H153F, and Y149F/H153F were constructed and purified. The structure of the Y149F mutant was solved by molecular replacement and refined to 2.0 A resolution. Comparison with the structure of wild-type StEH1 revealed only subtle structural differences. The hydroxyl group lost as a result of the mutation was replaced by a water molecule, thus maintaining a functioning hydrogen bond network in the proton wire. All mutants showed decreased catalytic efficiencies with the R,R-enantiomer of trans-stilbene oxide, whereas with the S,S-enantiomer, k (cat)/K (M) was similar or slightly increased compared with the wild-type reactions. k (cat) for the Y149F mutant with either TSO enantiomer was increased; thus the lowered enzyme efficiencies were due to increases in K (M). Thermal inactivation studies revealed that the mutated enzymes were more sensitive to elevated temperatures than the wild-type enzyme. Hence, structural alterations affecting the hydrogen bond chain caused increases in k (cat) but lowered thermostability.

The replacement child. Variations on a theme in history and psychoanalysis.

PubMed

Anisfeld, L; Richards, A D

2000-01-01

This paper reviews the literature on the replacement child syndrome and examines its historical, theoretical, and biographical ramifications. Although a replacement child in a literal sense is one conceived to take the place of a deceased sibling, the concept may be extended to many other situations in which a child is put in the place of someone else in the family system. In his experience of survivor guilt for his deceased brother Julius, Freud may be regarded as such a metaphorical replacement child. The collective tragedy of the Holocaust gives the replacement child concept a special meaning, since the children born in its aftermath had to fill the void in the lives not only of individual parents but of the Jewish people as a whole. One of the coauthors of this paper, Leon Anisfeld, was born after World War II to parents who had lost previous spouses and children, and his personal experience as a replacement child informs the theoretical issues considered here.

12 CFR 615.5130 - Procedures.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Procedures. 615.5130 Section 615.5130 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM FUNDING AND FISCAL AFFAIRS, LOAN POLICIES AND..., pricing, payment of interest, redemption, replacement of lost or stolen bonds and other matters shall be...

Food-dependent, exercise-induced gastrointestinal distress.

PubMed

de Oliveira, Erick Prado; Burini, Roberto Carlos

2011-09-28

Among athletes strenuous exercise, dehydration and gastric emptying (GE) delay are the main causes of gastrointestinal (GI) complaints, whereas gut ischemia is the main cause of their nausea, vomiting, abdominal pain and (blood) diarrhea. Additionally any factor that limits sweat evaporation, such as a hot and humid environment and/or body dehydration, has profound effects on muscle glycogen depletion and risk for heat illness. A serious underperfusion of the gut often leads to mucosal damage and enhanced permeability so as to hide blood loss, microbiota invasion (or endotoxemia) and food-born allergen absorption (with anaphylaxis). The goal of exercise rehydration is to intake more fluid orally than what is being lost in sweat. Sports drinks provide the addition of sodium and carbohydrates to assist with intestinal absorption of water and muscle-glycogen replenishment, respectively. However GE is proportionally slowed by carbohydrate-rich (hyperosmolar) solutions. On the other hand, in order to prevent hyponatremia, avoiding overhydration is recommended. Caregiver's responsibility would be to inform athletes about potential dangers of drinking too much water and also advise them to refrain from using hypertonic fluid replacements.

Food-dependent, exercise-induced gastrointestinal distress

PubMed Central

2011-01-01

Among athletes strenuous exercise, dehydration and gastric emptying (GE) delay are the main causes of gastrointestinal (GI) complaints, whereas gut ischemia is the main cause of their nausea, vomiting, abdominal pain and (blood) diarrhea. Additionally any factor that limits sweat evaporation, such as a hot and humid environment and/or body dehydration, has profound effects on muscle glycogen depletion and risk for heat illness. A serious underperfusion of the gut often leads to mucosal damage and enhanced permeability so as to hide blood loss, microbiota invasion (or endotoxemia) and food-born allergen absorption (with anaphylaxis). The goal of exercise rehydration is to intake more fluid orally than what is being lost in sweat. Sports drinks provide the addition of sodium and carbohydrates to assist with intestinal absorption of water and muscle-glycogen replenishment, respectively. However GE is proportionally slowed by carbohydrate-rich (hyperosmolar) solutions. On the other hand, in order to prevent hyponatremia, avoiding overhydration is recommended. Caregiver's responsibility would be to inform athletes about potential dangers of drinking too much water and also advise them to refrain from using hypertonic fluid replacements. PMID:21955383

Combined sample collection and gas extraction for the measurement of helium isotopes and neon in natural waters

NASA Astrophysics Data System (ADS)

Roether, Wolfgang; Vogt, Martin; Vogel, Sandra; Sültenfuß, Jürgen

2013-06-01

We present a new method to obtain samples for the measurement of helium isotopes and neon in water, to replace the classical sampling procedure using clamped-off Cu tubing containers that we have been using so far. The new method saves the gas extraction step prior to admission to the mass spectrometer, which the classical method requires. Water is drawn into evacuated glass ampoules with subsequent flame sealing. Approximately 50% headspace is left, from which admission into the mass spectrometer occurs without further treatment. Extensive testing has shown that, with due care and with small corrections applied, the samples represent the gas concentrations in the water within ±0.07% (95% confidence level; ±0.05% with special handling). Fast evacuation is achieved by pumping on a small charge of water placed in the ampoule. The new method was successfully tested at sea in comparison with Cu-tubing sampling. We found that the ampoule samples were superior in data precision and that a lower percentage of samples were lost prior to measurement. Further measurements revealed agreement between the two methods in helium, 3He and neon within ±0.1%. The new method facilitates the dealing with large sample sets and minimizes the delay between sampling and measurement. The method is applicable also for gases other than helium and neon.

Potential effects of surface coal mining on the hydrology of the West Otter area, Ashland and Birney-Broadus coal fields, southeastern Montana

USGS Publications Warehouse

McClymonds, N.E.

1984-01-01

Shallow aquifers exist primarily within the Tongue River Member of the Paleocene Fort Union Formation and within valley alluvium. Sandstone beds are the principal aquifers for domestic supply and livestock watering, with the Knobloch coal bed being a secondary source of supply. Surface-water resources consist principally of perennial flow in Otter Creek and intermittent flow in eight small drainage basins. The small streams are generally dry at their mouth, except after intense rainfall or sudden snowmelt. Otter Creek is used for livestock watering and, during spring floods, for irrigating alfalfa fields. The water supplied by wells generally is a sodium bicarbonate type. Dissolved-solids concentrations of water samples ranged from 480 to 3,460 milligrams per liter in sandstone beds and from 910 to 6,260 milligrams per liter in the Knobloch coal bed. Water in Otter Creek contains principally sodium, magnesium, and sulfate ions. The dissolved-solids concentration ranged from 2,050 to 2 ,950 milligrams per liter. Mining of the Knobloch coal bed would remove three private wells and adversely affect the yield of two other wells. After mining, water in the alluvium of Otter Creek might show long-term degradation in water quality as a result of waters leaching the soluble salts from the spoils material used to backfill the mine pits. Although mining would alter the existing hydrologic systems and remove several shallow wells, alternative ground-water supplies are available from deeper aquifers that could be developed to replace those lost by mining. (USGS)

Water relations during desiccation of cysts of the potato-cyst nematode Globodera rostochiensis.

PubMed

Wharton, D A; Worland, M R

2001-03-01

The loss during desiccation of osmotically active water (OAW), which freezes during cooling to -45 degrees C, and osmotically inactive water (OIW), which remains unfrozen, from the cysts of the potato cyst nematode, Globodera rostochiensis, was determined using differential scanning calorimetry. Exotherms and endotherms associated with non-egg compartments were not detected after 5 min desiccation at 50% relative humidity and 20 degrees C. The pattern of water loss from the cysts indicates that water is lost from compartments outside the eggs first, that nearly all the non-egg water is OAW and that the OIW content of the cyst is contained within the eggs. Water is lost from the eggs only after the OAW content outside the eggs falls below that within the eggs. Both OAW and OIW are lost from the eggs during desiccation but the eggs retain a small amount of OIW. Other animals which survive some desiccation but which are not anhydrobiotic will tolerate the loss of OAW but not the loss of their OIW. Anhydrobiotic animals can survive the loss of both their OAW and a substantial proportion of their OIW.

SYSTEM LEVEL IMPLICATIONS OF FLEXIBLE CO2 CAPTURE OPERATION

EPA Science Inventory

In ERCOT, turning flexible CO₂ capture systems off during infrequent periods of peak electricity demand can avoid hundreds of millions to billions of dollars in capital costs to replace the power output lost to CO₂ capture energy requirements.  When CO...

Insurers Relax Rules, Help Members After Hurricanes Harvey, Irma.

PubMed

Greene, Jan

2017-10-01

Some health plans responded by making it easier to see an out-of-network doctor, get a new copy of an insurance card or replace prescriptions lost in the chaos. Insurers also set up telephone help lines and made it easier to get a referral to a specialist.

Potential deaths averted in USA by replacing cigarettes with e-cigarettes

PubMed Central

Levy, David T; Borland, Ron; Lindblom, Eric N; Goniewicz, Maciej L; Meza, Rafael; Holford, Theodore R; Yuan, Zhe; Luo, Yuying; O’Connor, Richard J; Niaura, Raymond; Abrams, David B

2018-01-01

Introduction US tobacco control policies to reduce cigarette use have been effective, but their impact has been relatively slow. This study considers a strategy of switching cigarette smokers to e-cigarette use (‘vaping’) in the USA to accelerate tobacco control progress. Methods A Status Quo Scenario, developed to project smoking rates and health outcomes in the absence of vaping, is compared with Substitution models, whereby cigarette use is largely replaced by vaping over a 10-year period. We test an Optimistic and a Pessimistic Scenario, differing in terms of the relative harms of e-cigarettes compared with cigarettes and the impact on overall initiation, cessation and switching. Projected mortality outcomes by age and sex under the Status Quo and E-Cigarette Substitution Scenarios are compared from 2016 to 2100 to determine public health impacts. Findings Compared with the Status Quo, replacement of cigarette by e-cigarette use over a 10-year period yields 6.6 million fewer premature deaths with 86.7 million fewer life years lost in the Optimistic Scenario. Under the Pessimistic Scenario, 1.6 million premature deaths are averted with 20.8 million fewer life years lost. The largest gains are among younger cohorts, with a 0.5 gain in average life expectancy projected for the age 15 years cohort in 2016. Conclusions The tobacco control community has been divided regarding the role of e-cigarettes in tobacco control. Our projections show that a strategy of replacing cigarette smoking with vaping would yield substantial life year gains, even under pessimistic assumptions regarding cessation, initiation and relative harm. PMID:28970328

Development of teeth in chick embryos after mouse neural crest transplantations.

PubMed

Mitsiadis, Thimios A; Chéraud, Yvonnick; Sharpe, Paul; Fontaine-Pérus, Josiane

2003-05-27

Teeth were lost in birds 70-80 million years ago. Current thinking holds that it is the avian cranial neural crest-derived mesenchyme that has lost odontogenic capacity, whereas the oral epithelium retains the signaling properties required to induce odontogenesis. To investigate the odontogenic capacity of ectomesenchyme, we have used neural tube transplantations from mice to chick embryos to replace the chick neural crest cell populations with mouse neural crest cells. The mouse/chick chimeras obtained show evidence of tooth formation showing that avian oral epithelium is able to induce a nonavian developmental program in mouse neural crest-derived mesenchymal cells.

An investigation into denture loss in hospitals in Kent, Surrey and Sussex.

PubMed

Mann, J; Doshi, M

2017-08-25

Background The loss of dentures for inpatients can have a detrimental effect on their well-being. Self-respect and dignity become compromised along with their ability to eat meals and communicate clearly, and long-term recovery.Aim This investigation aimed to identify the reported number of dentures lost in hospitals and the financial reimbursements given by trusts to replace them.Method Information on reported denture loss and reimbursement was collected in 12 trusts throughout Kent, Surrey and Sussex.Results Eleven out of 12 trusts returned data about how many dentures were lost in their hospitals, between them 695 dentures were reported lost over five years (2011-16). Seven trusts reported financial reimbursements for dentures losses; results showed £357,672 was reimbursed over six years (2010-16), the highest amount reimbursed for a single denture was £2,200.Conclusion The results indicate that denture loss is a problem in hospitals that contributes to the financial burden for the NHS. Consideration needs to be given by hospitals to find ways to reduce the number of dentures lost every year.

14 CFR 63.16 - Change of name; replacement of lost or destroyed certificate.

Code of Federal Regulations, 2014 CFR

2014-01-01

... destroyed certificate. 63.16 Section 63.16 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT... certificate is made by letter to the Department of Transportation, Federal Aviation Administration, Airman... regarding the grade, number, and date of issue of the certificate, and the ratings on it; and (2) Be...

14 CFR 63.16 - Change of name; replacement of lost or destroyed certificate.

Code of Federal Regulations, 2012 CFR

2012-01-01

... destroyed certificate. 63.16 Section 63.16 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT... certificate is made by letter to the Department of Transportation, Federal Aviation Administration, Airman... regarding the grade, number, and date of issue of the certificate, and the ratings on it; and (2) Be...

14 CFR 63.16 - Change of name; replacement of lost or destroyed certificate.

Code of Federal Regulations, 2013 CFR

2013-01-01

... destroyed certificate. 63.16 Section 63.16 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT... certificate is made by letter to the Department of Transportation, Federal Aviation Administration, Airman... regarding the grade, number, and date of issue of the certificate, and the ratings on it; and (2) Be...

14 CFR 63.16 - Change of name; replacement of lost or destroyed certificate.

Code of Federal Regulations, 2010 CFR

2010-01-01

... destroyed certificate. 63.16 Section 63.16 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT... certificate is made by letter to the Department of Transportation, Federal Aviation Administration, Airman... regarding the grade, number, and date of issue of the certificate, and the ratings on it; and (2) Be...

The Family and Friends Plan: Grateful to Be Engaged, Parents, Grandparents, and Friends Happily Give

ERIC Educational Resources Information Center

Lum, Lydia

2011-01-01

Growing numbers of colleges and universities, as well as independent schools, are targeting parents, grandparents, and other nonalumni friends for gifts to meet institutional needs and, at many public institutions, replace appropriations lost to Draconian state cuts. Such efforts have taken root despite parents shouldering ever-climbing college…

Management strategies for improving lifetime reproductive success in beef heifers

USDA-ARS?s Scientific Manuscript database

Research has indicated it takes the net revenue from approximately 6 calves to cover the development and production costs of each replacement heifer (E. M. Mousel, unpublished data). In addition, any cow that misses a single calving is not likely to recover the lost revenue of that missed calf (Mat...

Ecosystem development after mangrove creation: plant-soil change across a twenty-year chronosequence in Tampa Bay, FL

EPA Science Inventory

On a global scale, the loss of mangroves has been high (~1-2% loss per year in recent decades). Recognizing the important ecosystem services supported by mangroves, restoration and creation efforts are increasingly proposed as mechanisms to replace those services lost after mangr...

14 CFR 1261.109 - Computation of allowance.

Code of Federal Regulations, 2011 CFR

2011-01-01

... to the loss or damage of property lost or damaged beyond economical repair, less any salvage value... price paid in cash or property, or the value at the time of acquisition if not acquired by purchase or exchange). There will be no allowance for replacement cost or for appreciation in the value of the property...

24 CFR 17.48 - Computation of amount of award.

Code of Federal Regulations, 2011 CFR

2011-04-01

... loss or damage, of property lost or damaged beyond economical repair, less any salvage value; or (2... property, or the value at the time of acquisition if not acquired by purchase or exchange); and there will be no allowance for replacement cost or for appreciation in the value of the property. Subject to...

Potential effects of surface coal mining on the hydrology of the Corral Creek area, Hanging Woman Creek coal field, southeastern Montana

USGS Publications Warehouse

McClymonds, N.E.

1984-01-01

The Corral Creek area of the Hanging Woman Creek coal field, 9 miles east of the Decker coal mines near the Tongue River, contains large reserves of Federal coal that have been identified for potential lease sale. A hydrologic study was conducted in the area to describe existing hydrologic systems and to study assess potential impacts of surface coal mining on local water resources. Hydrogeologic data collected indicate that aquifers are coal and sandstone beds within the Tongue River Member of the Fort Union Formation (Paleocene age) and sand and gravel in valley alluvium (Pleistocene and Holocene age). Surface-water resources are limited to a few spring-fed stock ponds in the higher parts of the area and the intermittent flow of Corral Creek near the mouth. Most of the stock ponds in the area become dry by midsummer. Mining of the Anderson coal bed would remove three stock wells and would lower the potentiometric surface within the coal and sandstone aquifers. The alluvial aquifer beneath Corral Creek and South Fork would be removed. Although mining would alter the existing hydrologic systems and remove several shallow wells, alternative ground-water supplies are available that could be developed to replace those lost by mining. (USGS)

[Pulley for strengthening a muscle replacement operation across two joints in brachial plexus lesion: description of the surgical technique].

PubMed

Berger, A; Schaller, E; Becker, M H

1994-01-01

The reconstruction of lost muscle functions in cases of brachial plexus lesion is possible even in those cases where primary nerve reconstruction was not performed or unsuccessful. If there are only few motor nerves available, we prefer free latissimus dorsi transplantation or pedicled latissimus dorsi transposition for replacement of biceps and finger flexors. The combination of elbow flexion and finger flexion becomes possible when the transposed motor is passed around a suitable pulley in the elbow region like the flexor carpi ulnaris or carpi radialis.

The lost value of groundwater and its influence on environmental decision making.

PubMed

Paleologos, Evan K

2008-08-01

A critical aspect in establishing environmental policies lies in the proper assessment of the value of the resource being affected. Standard risk assessment analyses calculate the cost of pollution as consisting, solely, of the cost to remediate a site. This traditional definition is extended here to include the lost value of groundwater. These concepts and their impact on decision-making analyses are illustrated through the case of municipal waste landfills. Based on data from existing polluting sites, a simple cost-benefit probabilistic analysis is conducted first, which equates, as is the practice, the cost of pollution to that of remediation. This leads rationally to selection of the lowest-protection technology. Using plausible arguments the reduction in value of groundwater from potable high-quality water to irrigation water, which is what is returned after remediation, is argued. The arguments consist of: (a) the ratio of the subsidized prices of drinking to irrigation water reflects the relative value of the use of water; (b) the amount paid for remediation, in each case, represents, at a minimum, the value of the water recovered; and (c) the lost value of groundwater equals the value of drinking water minus the value of irrigation water. Incorporation of this lost value of groundwater is sufficient to drastically alter the conclusions of the decision-making analysis and make the highest level technology the most rational and profitable alternative. The broader point of this article lies in that proper accounting of environmental costs is necessary in order to alter environmental policies and practices.

Therapeutic application of neural stem cells and adult neurogenesis for neurodegenerative disorders: regeneration and beyond.

PubMed

Latchney, Sarah E; Eisch, Amelia J

With the growth of the aging population and increasing life expectancy, the diagnosis of age-related neurodegenerative diseases is predicted to increase 12% by 2030. There is urgent need to develop better and novel treatments for disorders like Alzheimer's, Huntington's, and Parkinson's diseases. As these neurodegenerative diseases are customarily defined by the progressive loss of neurons, treatment strategies have traditionally focused on replacing neurons lost during disease progression. To this end, the self-renewing and multipotent properties of neural stem/precursor cells (NSPCs) that exist in the adult brain suggest that NSPCs could contribute to a therapy for replacement of damaged or lost neurons. Although a wealth of research demonstrates the proof-of-concept that NSPC transplantation has therapeutic potential, there are considerable barriers between the theory of cell transplantation and clinical implementation. However, a new view on harnessing the power of NSPC for treatment of neurodegenerative disorders has emerged, and focuses on treating neuropathological aspects of the disease prior to the appearance of overt neuronal loss. For example, rather than merely replacing lost neurons, NSPCs are now being considered for their ability to provide trophic support. Here we review the evolution of how the field has considered application of NSPCs for treatment of neurodegeneration disorders. We discuss the challenges posed by the "traditional" view of neurodegeneration - overt cell loss - for utilization of NSPCs for treatment of these disorders. We also review the emergence of an alternative strategy that involves fine-tuning the neurogenic capacity of existing adult NSPCs so that they are engineered to address disease-specific pathologies at specific time points during the trajectory of disease. We conclude with our opinion that for this strategy to become a translational reality, it requires a thorough understanding of NSPCs, the dynamic process of adult neurogenesis, and a better understanding of the pathological trajectory of each neurodegenerative disease.

Using spatial, seasonal, and diel drift patterns of larval Lost River suckers Deltistes luxatus (Cypriniformes: Catostomidae) and shortnose suckers Chasmistes brevirostris (Cypriniformes: Catostomidae) to help identify a site for a water withdrawal structure on the Williamson River, Oregon

USGS Publications Warehouse

Ellsworth, Craig M.; Tyler, Torrey J.; VanderKooi, Scott P.

2010-01-01

A small irrigation diversion dam near Chiloquin, Oregon, was removed and replaced with a pump station to improve fish passage for Lost River suckers (Deltistes luxatus) and shortnose suckers (Chasmistes brevirostris) entering the Sprague River on their spawning migrations. During the developmental phase of the pump station, a need was identified to better understand the larval drift characteristics of these endangered catostomids in order to reduce entrainment into the irrigation system. The spatial, seasonal, and diel distribution of drifting larvae was measured during the 2004 spawning season at two proposed sites on the Williamson River where the pump station could be located. Larval drift for both species coincided with the irrigation season making them subject to entrainment into the irrigation system. Drift occurred almost exclusively at night with larvae entering the drift at sunset and exiting the drift at sunrise. Nighttime larval densities were concentrated near the surface and at midchannel at both sites. Densities were generally greater on the side of mid-channel with greater flow. During early morning sampling we detected a general shift in larval drift from surface to subsurface drift. We also observed an increase in larval densities towards the shore opposite from the proposed pump station at the upper site whereas larval densities remained high at midchannel at the lower site. During daytime sampling, the few larvae that were collected were distributed throughout the water column at both pump sites. This study found that larvae drifting during all time periods were generally distributed further across the cross section, deeper in the water column, and closer to where the proposed water withdrawal structure would be built at the downstream site when compared to the upstream site. Recommendations were provided to locate the withdrawal facility at the upstream site and operate it in a manner such that larval entrainment would likely be minimized.

Road deicing salt irreversibly disrupts osmoregulation of salamander egg clutches.

PubMed

Karraker, Nancy E; Gibbs, James P

2011-03-01

It has been postulated that road deicing salts are sufficiently diluted by spring rains to ameliorate any physiological impacts to amphibians breeding in wetlands near roads. We tested this conjecture by exposing clutches of the spotted salamander (Ambystoma maculatum) to three chloride concentrations (1 mg/L, 145 mg/L, 945 mg/L) for nine days, then transferred clutches to control water for nine days, and measured change in mass at three-day intervals. We measured mass change because water uptake by clutches reduces risks to embryos associated with freezing, predation, and disease. Clutches in controls sequestered water asymptotically. Those in the moderate concentrations lost 18% mass initially and regained 14% after transfer to control water. Clutches in high concentration lost 33% mass and then lost an additional 8% after transfer. Our results suggest that spring rains do not ameliorate the effects of deicing salts in wetlands with extremely high chloride concentrations. Copyright © 2010 Elsevier Ltd. All rights reserved.

Cell replacement and visual restoration by retinal sheet transplants

PubMed Central

Seiler, Magdalene J.; Aramant, Robert B.

2012-01-01

Retinal diseases such as age-related macular degeneration (ARMD) and retinitis pigmentosa (RP) affect millions of people. Replacing lost cells with new cells that connect with the still functional part of the host retina might repair a degenerating retina and restore eyesight to an unknown extent. A unique model, subretinal transplantation of freshly dissected sheets of fetal-derived retinal progenitor cells, combined with its retinal pigment epithelium (RPE), has demonstrated successful results in both animals and humans. Most other approaches are restricted to rescue endogenous retinal cells of the recipient in earlier disease stages by a ‘nursing’ role of the implanted cells and are not aimed at neural retinal cell replacement. Sheet transplants restore lost visual responses in several retinal degeneration models in the superior colliculus (SC) corresponding to the location of the transplant in the retina. They do not simply preserve visual performance – they increase visual responsiveness to light. Restoration of visual responses in the SC can be directly traced to neural cells in the transplant, demonstrating that synaptic connections between transplant and host contribute to the visual improvement. Transplant processes invade the inner plexiform layer of the host retina and form synapses with presumable host cells. In a Phase II trial of RP and ARMD patients, transplants of retina together with its RPE improved visual acuity. In summary, retinal progenitor sheet transplantation provides an excellent model to answer questions about how to repair and restore function of a degenerating retina. Supply of fetal donor tissue will always be limited but the model can set a standard and provide an informative base for optimal cell replacement therapies such as embryonic stem cell (ESC)-derived therapy. PMID:22771454

Potential deaths averted in USA by replacing cigarettes with e-cigarettes.

PubMed

Levy, David T; Borland, Ron; Lindblom, Eric N; Goniewicz, Maciej L; Meza, Rafael; Holford, Theodore R; Yuan, Zhe; Luo, Yuying; O'Connor, Richard J; Niaura, Raymond; Abrams, David B

2018-01-01

US tobacco control policies to reduce cigarette use have been effective, but their impact has been relatively slow. This study considers a strategy of switching cigarette smokers to e-cigarette use ('vaping') in the USA to accelerate tobacco control progress. A Status Quo Scenario, developed to project smoking rates and health outcomes in the absence of vaping, is compared with Substitution models, whereby cigarette use is largely replaced by vaping over a 10-year period. We test an Optimistic and a Pessimistic Scenario, differing in terms of the relative harms of e-cigarettes compared with cigarettes and the impact on overall initiation, cessation and switching. Projected mortality outcomes by age and sex under the Status Quo and E-Cigarette Substitution Scenarios are compared from 2016 to 2100 to determine public health impacts. Compared with the Status Quo, replacement of cigarette by e-cigarette use over a 10-year period yields 6.6 million fewer premature deaths with 86.7 million fewer life years lost in the Optimistic Scenario. Under the Pessimistic Scenario, 1.6 million premature deaths are averted with 20.8 million fewer life years lost. The largest gains are among younger cohorts, with a 0.5 gain in average life expectancy projected for the age 15 years cohort in 2016. The tobacco control community has been divided regarding the role of e-cigarettes in tobacco control. Our projections show that a strategy of replacing cigarette smoking with vaping would yield substantial life year gains, even under pessimistic assumptions regarding cessation, initiation and relative harm. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Unwinding Madness: What Went Wrong with College Sports--and How to Fix It

ERIC Educational Resources Information Center

Gurney, Gerald; Lopiano, Donna A.; Zimbalist, Andrew

2017-01-01

"Unwinding Madness" is the most comprehensive examination to date of how the NCAA has lost its way in the governance of intercollegiate athletics--and why it is incapable of achieving reform and must be replaced. The NCAA has placed commercial success above its responsibilities to protect the academic primacy, health and well-being of…

22 CFR 62.12 - Control of Forms DS-2019.

Code of Federal Regulations, 2010 CFR

2010-04-01

... transfer; (4) Replace a lost or stolen Form DS-2019; (5) Facilitate entry of an exchange visitor's alien spouse or minor unmarried children into the United States separately; (6) Facilitate re-entry of an... Form DS-2019. Issue the Form DS-2019 only so as to: (1) Facilitate the entry of a new participant of...

22 CFR 62.12 - Control of Forms DS-2019.

Code of Federal Regulations, 2013 CFR

2013-04-01

... transfer; (4) Replace a lost or stolen Form DS-2019; (5) Facilitate entry of an exchange visitor's alien spouse or minor unmarried children into the United States separately; (6) Facilitate re-entry of an... Form DS-2019. Issue the Form DS-2019 only so as to: (1) Facilitate the entry of a new participant of...

22 CFR 62.12 - Control of Forms DS-2019.

Code of Federal Regulations, 2011 CFR

2011-04-01

... transfer; (4) Replace a lost or stolen Form DS-2019; (5) Facilitate entry of an exchange visitor's alien spouse or minor unmarried children into the United States separately; (6) Facilitate re-entry of an... Form DS-2019. Issue the Form DS-2019 only so as to: (1) Facilitate the entry of a new participant of...

22 CFR 62.12 - Control of Forms DS-2019.

Code of Federal Regulations, 2014 CFR

2014-04-01

... transfer; (4) Replace a lost or stolen Form DS-2019; (5) Facilitate entry of an exchange visitor's alien spouse or minor unmarried children into the United States separately; (6) Facilitate re-entry of an... Form DS-2019. Issue the Form DS-2019 only so as to: (1) Facilitate the entry of a new participant of...

22 CFR 62.12 - Control of Forms DS-2019.

Code of Federal Regulations, 2012 CFR

2012-04-01

... transfer; (4) Replace a lost or stolen Form DS-2019; (5) Facilitate entry of an exchange visitor's alien spouse or minor unmarried children into the United States separately; (6) Facilitate re-entry of an... Form DS-2019. Issue the Form DS-2019 only so as to: (1) Facilitate the entry of a new participant of...

Forest restoration and forest communities: Have local communities benefited from forest service contracting of ecosystem management?

Treesearch

Cassandra Moseley; Yolanda E. Reyes

2008-01-01

Conservation-based development programs have sought to create economic opportunities for people negatively affected by biological diversity protection. The USDA Forest Service, for example, developed policies and programs to create contracting opportunities for local communities to restore public lands to replace jobs lost from reduced timber harvest. This article...

30 CFR 938.12 - State statutory, regulatory, and proposed program amendment provisions not approved.

Code of Federal Regulations, 2010 CFR

2010-07-01

... extent that it would allow the replaced water supply to be of a lesser quantity and quality than the premining water supply or does not provide for temporary replacement of water supplies. We are not approving Subsection (a)(1)(v) to the extent it would pass on operating and maintenance costs of a replacement water...

Hydrogeology and steady-state numerical simulation of groundwater flow in the Lost Creek Designated Ground Water Basin, Weld, Adams, and Arapahoe Counties, Colorado

USGS Publications Warehouse

Arnold, L.R.

2010-01-01

The Lost Creek Designated Ground Water Basin (Lost Creek basin) is an important alluvial aquifer for irrigation, public supply, and domestic water uses in northeastern Colorado. Beginning in 2005, the U.S. Geological Survey, in cooperation with the Lost Creek Ground Water Management District and the Colorado Water Conservation Board, collected hydrologic data and constructed a steady-state numerical groundwater flow model of the Lost Creek basin. The model builds upon the work of previous investigators to provide an updated tool for simulating the potential effects of various hydrologic stresses on groundwater flow and evaluating possible aquifer-management strategies. As part of model development, the thickness and extent of regolith sediments in the basin were mapped, and data were collected concerning aquifer recharge beneath native grassland, nonirrigated agricultural fields, irrigated agricultural fields, and ephemeral stream channels. The thickness and extent of regolith in the Lost Creek basin indicate the presence of a 2- to 7-mile-wide buried paleovalley that extends along the Lost Creek basin from south to north, where it joins the alluvial valley of the South Platte River valley. Regolith that fills the paleovalley is as much as about 190 ft thick. Average annual recharge from infiltration of precipitation on native grassland and nonirrigated agricultural fields was estimated by using the chloride mass-balance method to range from 0.1 to 0.6 inch, which represents about 1-4 percent of long-term average precipitation. Average annual recharge from infiltration of ephemeral streamflow was estimated by using apparent downward velocities of chloride peaks to range from 5.7 to 8.2 inches. Average annual recharge beneath irrigated agricultural fields was estimated by using passive-wick lysimeters and a water-balance approach to range from 0 to 11.3 inches, depending on irrigation method, soil type, crop type, and the net quantity of irrigation water applied. Estimated average annual recharge beneath irrigated agricultural fields represents about 0-43 percent of net irrigation. The U.S. Geological Survey modular groundwater modeling program, MODFLOW-2000, was used to develop a steady-state groundwater flow model of the Lost Creek basin. Groundwater in the basin is simulated generally to flow from the basin margins toward the center of the basin and northward along the paleovalley. The largest source of inflow to the model occurs from recharge beneath flood- and sprinkler-irrigated agricultural fields (14,510 acre-feet per year [acre-ft/yr]), which represents 39.7 percent of total simulated inflow. Other substantial sources of inflow to the model are recharge from precipitation and stream-channel infiltration in nonirrigated areas (13,810 acre-ft/yr) seepage from Olds Reservoir (4,280 acre-ft/yr), and subsurface inflow from ditches and irrigated fields outside the model domain (2,490 acre-ft/yr), which contribute 37.7, 11.7, and 6.8 percent, respectively, of total inflow. The largest outflow from the model occurs from irrigation well withdrawals (26,760 acre-ft/yr), which represent 73.2 percent of total outflow. Groundwater discharge (6,640 acre-ft/yr) at the downgradient end of the Lost Creek basin represents 18.2 percent of total outflow, and evapotranspiration (3,140 acre-ft/yr) represents about 8.6 percent of total outflow.

Characterization of a water-solid interaction in a partially ordered system.

PubMed

Chakravarty, Paroma; Lubach, Joseph W

2013-11-04

GNE068-PC, a developmental compound, was previously characterized to be mesomorphous, i.e. having long-range order associated with significant local molecular disorder (Chakravarty et. al., Mol. Pharmaceutics, accepted). The compound was exposed to moisture under different relative humidity conditions ranging from 11% to 60% RH at room temperature (RT) for 7 days, and the resultant product phases were characterized. The partially ordered sample progressively lost crystallinity (long-range order) and birefringence (orientational order) upon exposure to increasing RH conditions, leading to the formation of a completely disordered amorphous phase at 60% RH (RT). Long-range positional order was irrecoverable even after moisture removal from the sample exposed to 60% RH. This was attributed to replacement of residual ethyl acetate by water, the former being critical for maintenance of long-range order in the material. In addition, water sorption appeared to irreversibly alter the molecular orientation, thereby affecting sample birefringence. Solid-state NMR revealed increases in (1)H and (13)C spin-lattice relaxation times (T1) going from the mesomorphous phase to the fully amorphous phase. This was indicative of reduction in lattice mobility, likely due to the decreased motion of the aromatic portions of the molecule, in particular C17, which showed the most dramatic increase in (13)C T1. This is likely due to decrease in available free volume upon water sorption. Drying of the hydrated disordered phase showed somewhat greater mobility than the hydrated phase, likely due to increased relative free volume through removal of water. A water-solid interaction therefore irreversibly changed the solid-state makeup of GNE068-PC.

The Observed State of the Water Cycle in the Early Twenty-First Century

NASA Technical Reports Server (NTRS)

Rodell, M.; Beaudoing, H. K.; L'Ecuyer, T. S.; Olson, W. S.; Famiglietti, J. S.; Houser, P. R.; Adler, R.; Bosilovich, M. G.; Clayson, C. A.; Chambers, D.;

Disinfection byproduct formation in reverse-osmosis concentrated and lyophilized natural organic matter from a drinking water source.

PubMed

Pressman, Jonathan G; McCurry, Daniel L; Parvez, Shahid; Rice, Glenn E; Teuschler, Linda K; Miltner, Richard J; Speth, Thomas F

2012-10-15

Drinking water treatment and disinfection byproduct (DBP) research can be complicated by natural organic matter (NOM) temporal variability. NOM preservation by lyophilization (freeze-drying) has been long practiced to address this issue; however, its applicability for drinking water research has been limited because the selected NOM sources are atypical of most drinking water sources. The purpose of this research was to demonstrate that reconstituted NOM from a lyophilized reverse-osmosis (RO) concentrate of a typical drinking water source closely represents DBP formation in the original NOM. A preliminary experiment assessed DBP formation kinetics and yields in concentrated NOM, which demonstrated that chlorine decays faster in concentrate, in some cases leading to altered DBP speciation. Potential changes in NOM reactivity caused by lyophilization were evaluated by chlorination of lyophilized and reconstituted NOM, its parent RO concentrate, and the source water. Bromide lost during RO concentration was replaced by adding potassium bromide prior to chlorination. Although total measured DBP formation tended to decrease slightly and unidentified halogenated organic formation tended to increase slightly as a result of RO concentration, the changes associated with lyophilization were minor. In lyophilized NOM reconstituted back to source water TOC levels and then chlorinated, the concentrations of 19 of 21 measured DBPs, constituting 96% of the total identified DBP mass, were statistically indistinguishable from those in the chlorinated source water. Furthermore, the concentrations of 16 of 21 DBPs in lyophilized NOM reconstituted back to the RO concentrate TOC levels, constituting 86% DBP mass, were statistically indistinguishable from those in the RO concentrate. This study suggests that lyophilization can be used to preserve concentrated NOM without substantially altering the precursors to DBP formation. Published by Elsevier Ltd.

Different architectures of creativity: Louis and Nathaniel Kahn.

PubMed

Golinelli, Paola

2014-04-01

The author analyzes Nathaniel Kahn's documentary film My Architect: A Son's Journey, a tribute to the writer-director's father Louis, the famous architect, who died suddenly when Nathaniel was eleven years old. The film's poetic, evocative images form a testimony to the silent working through that Nathaniel did in searching for his lost father and to the complex intertwining of mourning and creativity. Creativity is seen as both the cause and the effect of working through, as it gives life to a new meaning and allows replacement of the lost object by an object found again. Bereavement, symbolization, and the birth of representation appear to be connected with one another, both when the most elementary representations are involved and when the more complex and artistic ones are. Where and when it is possible to recover a representation that can survive the absence of the lost object, there is a potentially creative psychic space that can be made fertile again. © 2014 The Psychoanalytic Quarterly, Inc.

The evolution of milk secretion and its ancient origins.

PubMed

Oftedal, O T

2012-03-01

Lactation represents an important element of the life history strategies of all mammals, whether monotreme, marsupial, or eutherian. Milk originated as a glandular skin secretion in synapsids (the lineage ancestral to mammals), perhaps as early as the Pennsylvanian period, that is, approximately 310 million years ago (mya). Early synapsids laid eggs with parchment-like shells intolerant of desiccation and apparently dependent on glandular skin secretions for moisture. Mammary glands probably evolved from apocrine-like glands that combined multiple modes of secretion and developed in association with hair follicles. Comparative analyses of the evolutionary origin of milk constituents support a scenario in which these secretions evolved into a nutrient-rich milk long before mammals arose. A variety of antimicrobial and secretory constituents were co-opted into novel roles related to nutrition of the young. Secretory calcium-binding phosphoproteins may originally have had a role in calcium delivery to eggs; however, by evolving into large, complex casein micelles, they took on an important role in transport of amino acids, calcium and phosphorus. Several proteins involved in immunity, including an ancestral butyrophilin and xanthine oxidoreductase, were incorporated into a novel membrane-bound lipid droplet (the milk fat globule) that became a primary mode of energy transfer. An ancestral c-lysozyme lost its lytic functions in favor of a role as α-lactalbumin, which modifies a galactosyltransferase to recognize glucose as an acceptor, leading to the synthesis of novel milk sugars, of which free oligosaccharides may have predated free lactose. An ancestral lipocalin and an ancestral whey acidic protein four-disulphide core protein apparently lost their original transport and antimicrobial functions when they became the whey proteins β-lactoglobulin and whey acidic protein, which with α-lactalbumin provide limiting sulfur amino acids to the young. By the late Triassic period (ca 210 mya), mammaliaforms (mammalian ancestors) were endothermic (requiring fluid to replace incubatory water losses of eggs), very small in size (making large eggs impossible), and had rapid growth and limited tooth replacement (indicating delayed onset of feeding and reliance on milk). Thus, milk had already supplanted egg yolk as the primary nutrient source, and by the Jurassic period (ca 170 mya) vitellogenin genes were being lost. All primary milk constituents evolved before the appearance of mammals, and some constituents may have origins that predate the split of the synapsids from sauropsids (the lineage leading to 'reptiles' and birds). Thus, the modern dairy industry is built upon a very old foundation, the cornerstones of which were laid even before dinosaurs ruled the earth in the Jurassic and Cretaceous periods.

Loss to specialist follow-up in congenital heart disease; out of sight, out of mind

PubMed Central

Wray, Jo; Frigiola, Alessandra; Bull, Catherine

2013-01-01

Objective To evaluate the scale and clinical importance of loss to follow-up of past patients with serious congenital heart disease, using a common malformation as an example. To better understand the antecedents of loss to specialist follow-up and patients’ attitudes to returning. Design Cohort study using NHS number functionality. Content and thematic analysis of telephone interviews of subset contacted after loss to follow-up. Patients, intervention and setting Longitudinal follow-up of complete consecutive list of all 1085 UK patients with repair of tetralogy of Fallot from single institution 1964–2009. Main outcome measures Survival, freedom from late pulmonary valve replacement, loss to specialist follow-up, shortfall in late surgical revisions related to loss to follow-up. Patients’ narrative about loss to follow-up. Results 216 (24%) of patients known to be currently alive appear not to be registered with specialist clinics; some are seen in general cardiology clinics. Their median age is 32 years and median duration of loss to follow-up is 22 years; most had been lost before Adult Congenital services had been consolidated in their present form. 48% of the late deaths to date have occurred in patients not under specialist follow-up. None of those lost to specialist follow-up has had secondary pulmonary valve replacement while 188 patients under specialist care have. Patients lost to specialist follow-up who were contacted by telephone had no knowledge of its availability. Conclusions Loss to specialist follow-up, typically originating many years ago, impacts patient management. PMID:23257171

The economic cost of upland and gully erosion on subsistence agriculture for a watershed in the Ethiopian highlands

USDA-ARS?s Scientific Manuscript database

This paper quantifies the cost of erosion; it uses nutrient replacement cost to value topsoil nutrient depletion, daily wage rate to monetize the opportunity cost of labour due to gully erosion and local market price to quantify the lost animal and cash crop trees. Soil erosion rate is estimated fro...

Between Scylla and Charybdis: Theater Nuclear Forces in Europe.

DTIC Science & Technology

1985-03-01

Soviets lost what credibility they may have had in the wake of the KAL tragedy . The Soviets were also less than optimistic about their chances of...at Seneca Army Depot, NY. 30 The W82 ERW has a yield of < 2 KT and was intended to replace the W48. Costs have climbed to $3 mill. per warhead, but

Rewaterproofing Chemical For Use With Silicones

NASA Technical Reports Server (NTRS)

Hill, William L.; Mitchell, Shirley M.; Massey, Howard S.

1990-01-01

Agent restores impermeability without degrading silicone adhesives and substructures. Dimethylethoxysilane (DMES) found to rewaterproof tiles and composite panels internally without harming materials that underlie them. Replaces hexamethyldisilazane (HMDS) as postmission rewaterproofing agent for tiles of thermal-protection system on Space Shuttle. Much of original waterproofing lost during rigors of launch and reentry. Potential terrestrial application includes composite materials in such structures as bridges and submarines.

Role of Colonial Subjects in Making Themselves Inferior in Chinua Achebe's "Things Fall Apart"

ERIC Educational Resources Information Center

Sadeghi, Zahra

2014-01-01

Chinua Achebe in his novel "Things Fall Apart" gives us a unique picture of life in Africa before the arrival of Christianity and colonization and the era afterwards. He shows how African people lost their traditional culture and values, replacing them with foreign beliefs. In this article, the way black people lived before the arrival…

Recovery of neuronal and network excitability after spinal cord injury and implications for spasticity

PubMed Central

D'Amico, Jessica M.; Condliffe, Elizabeth G.; Martins, Karen J. B.; Bennett, David J.; Gorassini, Monica A.

2014-01-01

The state of areflexia and muscle weakness that immediately follows a spinal cord injury (SCI) is gradually replaced by the recovery of neuronal and network excitability, leading to both improvements in residual motor function and the development of spasticity. In this review we summarize recent animal and human studies that describe how motoneurons and their activation by sensory pathways become hyperexcitable to compensate for the reduction of functional activation of the spinal cord and the eventual impact on the muscle. Specifically, decreases in the inhibitory control of sensory transmission and increases in intrinsic motoneuron excitability are described. We present the idea that replacing lost patterned activation of the spinal cord by activating synaptic inputs via assisted movements, pharmacology or electrical stimulation may help to recover lost spinal inhibition. This may lead to a reduction of uncontrolled activation of the spinal cord and thus, improve its controlled activation by synaptic inputs to ultimately normalize circuit function. Increasing the excitation of the spinal cord with spared descending and/or peripheral inputs by facilitating movement, instead of suppressing it pharmacologically, may provide the best avenue to improve residual motor function and manage spasticity after SCI. PMID:24860447

Surface-water and karst groundwater interactions and streamflow-response simulations of the karst-influenced upper Lost River watershed, Orange County, Indiana

USGS Publications Warehouse

Bayless, E. Randall; Cinotto, Peter J.; Ulery, Randy L.; Taylor, Charles J.; McCombs, Gregory K.; Kim, Moon H.; Nelson, Hugh L.

2014-01-01

The U.S. Geological Survey (USGS), in cooperation with the U.S. Army Corps of Engineers (USACE) and the Indiana Office of Community and Rural Affairs (OCRA), conducted a study of the upper Lost River watershed in Orange County, Indiana, from 2012 to 2013. Streamflow and groundwater data were collected at 10 data-collection sites from at least October 2012 until April 2013, and a preliminary Water Availability Tool for Environmental Resources (WATER)-TOPMODEL based hydrologic model was created to increase understanding of the complex, karstic hydraulic and hydrologic system present in the upper Lost River watershed, Orange County, Ind. Statistical assessment of the optimized hydrologic-model results were promising and returned correlation coefficients for simulated and measured stream discharge of 0.58 and 0.60 and Nash-Sutcliffe efficiency values of 0.56 and 0.39 for USGS streamflow-gaging stations 03373530 (Lost River near Leipsic, Ind.), and 03373560 (Lost River near Prospect, Ind.), respectively. Additional information to refine drainage divides is needed before applying the model to the entire karst region of south-central Indiana. Surface-water and groundwater data were used to tentatively quantify the complex hydrologic processes taking place within the watershed and provide increased understanding for future modeling and management applications. The data indicate that during wet-weather periods and after certain intense storms, the hydraulic capacity of swallow holes and subsurface conduits is overwhelmed with excess water that flows onto the surface in dry-bed relic stream channels and karst paleovalleys. Analysis of discharge data collected at USGS streamflow-gaging station 03373550 (Orangeville Rise, at Orangeville, Ind.), and other ancillary data-collection sites in the watershed, indicate that a bounding condition is likely present, and drainage from the underlying karst conduit system is potentially limited to near 200 cubic feet per second. This information will direct future studies and assist managers in understanding when the subsurface conduits may become overwhelmed.

Periodontal and periimplant maintenance: a critical factor in long-term treatment success.

PubMed

Shumaker, Nicholas D; Metcalf, Brett T; Toscano, Nicholas T; Holtzclaw, Dan J

2009-09-01

Periodontal maintenance (PM) is a critical factor in the long-term success of both periodontal and dental implant therapy. Studies have shown both modern periodontal and dental implant therapies are effective in maintaining natural teeth and replacing lost teeth, respectively. However, without a regular program of clinical reevaluation, plaque control, oral hygiene instruction, and reassessment of biomechanical factors, the benefits of treatment often are lost and inflammatory disease in the form of recurrent periodontitis or periimplantitis may result. This article reviews the goals, types, and appropriate frequency of PM in periodontal and dental implant therapy, as well as the incidence and etiology of periimplant disease and strategies for management when recurrent disease develops during the maintenance phase of treatment.

Effect of oral calcium and calcium + fluoride treatments on mouse bone properties during suspension

NASA Technical Reports Server (NTRS)

Simske, S. J.; Luttges, M. W.; Allen, K. A.; Spooner, B. S. (Principal Investigator)

1992-01-01

The bone effects of oral dosages of calcium chloride with or without supplementary sodium fluoride were assessed in antiorthostatically suspended mice. Two calcium dosages were used to replace half (3.1 mM) or all(6.3 mM) of the dietary calcium lost due to reduced food intake by the suspended mice. Two groups of 6.3 mM CaCl2-treated mice were additionally treated with 0.25 or 2.5 mM NaF. The results indicate that supplementation of the mouse drinking water with calcium salts prevents bone changes induced by short-term suspension, while calcium salts in combination with fluoride are less effective as fluoride dosage increases. However, the calcium supplements change the relationship between the femur mechanical properties and the mineral composition of the bone. Because of this, it appears that oral calcium supplements are effective through a mechanism other than simple dietary supplementation and may indicate a dependence of bone consistency on systemic and local fluid conditions.

Role of a naturally varying flow regime in Everglades restoration

USGS Publications Warehouse

Harvey, Judson; Wetzel, Paul R.; Lodge, Thomas E.; Engel, Victor C.; Ross, Michael S.

2017-01-01

The Everglades is a low-gradient floodplain predominantly on organic soil that undergoes seasonally pulsing sheetflow through a network of deepwater sloughs separated by slightly higher elevation ridges. The seasonally pulsing flow permitted the coexistence of ridge and slough vegetation, including the persistence of productive, well-connected sloughs that seasonally concentrated prey and supported wading bird nesting success. Here we review factors contributing to the origin and to degradation of the ridge and slough ecosystem in an attempt to answer “How much flow is needed to restore functionality”? A key restoration objective is to increase sheetflow lost during the past century to reestablish interactions between flow, water depth, vegetation production and decomposition, and transport of flocculent organic sediment that build and maintain ridge and slough distinctions. Our review finds broad agreement that perturbations of water level depth and its fluctuations were primary in the degradation of landscape functions, with critical contributions from perturbed water quality, and flow velocity and direction. Whereas water levels are expected to be improved on average across a range of restoration scenarios that replace between 79 and 91% of predrainage flows, the diminished microtopography substantially decreases the probability of timely improvements in some areas whereas others that retain microtopographic differences are poised for restoration benefits. New advances in predicting restoration outcomes are coming from biophysical modeling of ridge–slough dynamics, system-wide measurements of landscape functionality, and large-scale flow restoration experiments, including active management techniques to kick-start slough regeneration.

Retempering of Concrete made by using Manufactured Sand

NASA Astrophysics Data System (ADS)

Pethkar, A. R.; Deshmukh, G.

2014-06-01

Retempering is defined as, " Addition of water and remixing of concrete or mortar which has lost enough workability to become unplaceable". Retempering inevitably results in some loss of strength compared with the original concrete [1]. Adding water to a plastic mix to increase slump is an extremely common practice, even though it is not recommended because it increases the porosity of concrete. Concrete often arrives on site more than half an hour after initial mixing. Placement operations can take anywhere from 10 to 60 min, depending on the field conditions and the size of the load. When the slump decreases to an unacceptable level during the operations, water is added to the mix [1]. In this work, an attempt is made to study the strength characteristics of retempered concrete made by using manufactured sand. Usually the retempering process is there with normal and ready mixed concrete; hence an attempt is made to check the compressive and flexural strength of normal retempered concrete with an addition of retarder 0.2, 0.4 and 0.6 % at retempering time from 15 to 90 min. There is scarcity of natural sand due to various factors, which is replaced by the manufactured sand. The concept of manufactured sand is nothing but breaking stone into smaller and smaller particles in such way that the gradation of particle will match with zone-II of I.S.

Consequences of Decapitation Policies

DTIC Science & Technology

2013-04-04

must not execute the targeted killing. • The targeted killing must not be conducted with “ poison , expanding bullets, or other prohibited weapons” under...responded with a never-ending string of poisonings , bombings, kidnappings, and shootings. Chechen militants continue to replace lost leaders. Over the...34 Aaron Mannes, “Testing the Snake Head Strategy: Does Killing or Capturing Its Leaders Reduce a Terrorist Group’s Activity?” Journal of

After-School All-Stars: Providing Structured Health and Physical Activity Programs in Urban Environments

ERIC Educational Resources Information Center

Thompson, Walter R.

2009-01-01

Physical education time has been reduced or even eliminated in middle and high schools in favor of more time for standardized test preparation, especially in urban schools and inner cities. One way to replace the time lost is by providing it after school as part of a comprehensive program. After-School All-Stars (ASAS) is such a program, networked…

Water resources in the Big Lost River Basin, south-central Idaho

USGS Publications Warehouse

Crosthwaite, E.G.; Thomas, C.A.; Dyer, K.L.

1970-01-01

The Big Lost River basin occupies about 1,400 square miles in south-central Idaho and drains to the Snake River Plain. The economy in the area is based on irrigation agriculture and stockraising. The basin is underlain by a diverse-assemblage of rocks which range, in age from Precambrian to Holocene. The assemblage is divided into five groups on the basis of their hydrologic characteristics. Carbonate rocks, noncarbonate rocks, cemented alluvial deposits, unconsolidated alluvial deposits, and basalt. The principal aquifer is unconsolidated alluvial fill that is several thousand feet thick in the main valley. The carbonate rocks are the major bedrock aquifer. They absorb a significant amount of precipitation and, in places, are very permeable as evidenced by large springs discharging from or near exposures of carbonate rocks. Only the alluvium, carbonate rock and locally the basalt yield significant amounts of water. A total of about 67,000 acres is irrigated with water diverted from the Big Lost River. The annual flow of the river is highly variable and water-supply deficiencies are common. About 1 out of every 2 years is considered a drought year. In the period 1955-68, about 175 irrigation wells were drilled to provide a supplemental water supply to land irrigated from the canal system and to irrigate an additional 8,500 acres of new land. Average. annual precipitation ranged from 8 inches on the valley floor to about 50 inches at some higher elevations during the base period 1944-68. The estimated water yield of the Big Lost River basin averaged 650 cfs (cubic feet per second) for the base period. Of this amount, 150 cfs was transpired by crops, 75 cfs left the basin as streamflow, and 425 cfs left as ground-water flow. A map of precipitation and estimated values of evapotranspiration were used to construct a water-yield map. A distinctive feature of the Big Lost River basin, is the large interchange of water from surface streams into the ground and from the ground into the surface streams. Large quantities of water disappear in the Chilly, Darlington, and other sinks and reappear above Mackay Narrows, above Moore Canal heading, and in other reaches. A cumulative summary of water yield upstream from selected points in the basin is as follows : Above Howell Ranch: water yield: 345 cfs; surface water: 310 cfs; ground water: 35 cfs Above. Mackay Narrows water yield: 450 cfs; surface water: 325 cfs; ground water: 75 cfs; crop evapotranspiration: 50 cfs Above Arco: water yield: 650 cfs; surface water: 75 cfs; ground water: 425 cfs; crop evapotranspiration: 150 cfs Ground-water pumping affects streamflow in reaches , where the stream and water table are continuous, but the effects of pumping were not measured except locally. Pumping depletes the total water supply by the. amount of the pumped water that is evapotranspired by crops. The part of the pumped water that is not consumed percolates into the ground or runs off over the land surface to the stream. The estimated 425 cfs that leaves the basin as ground-water flow is more than adequate for present and foreseeable needs. However because much of the outflow occurs at considerable depth, the quantity that is salvageable is unknown. Both the surface and ground waters are of good quality and are suitable for most uses. Although these waters are low in total dissolved solids, they tend to be hard or very hard.

Multilevel modeling of retention and disinfection efficacy of silver nanoparticles on ceramic water filters.

PubMed

Mikelonis, Anne M; Lawler, Desmond F; Passalacqua, Paola

2016-10-01

This research examined how variations in synthesis methods of silver nanoparticles affect both the release of silver from ceramic water filters (CWFs) and disinfection efficacy. The silver nanoparticles used were stabilized by four different molecules: citrate, polyvinylpyrrolidone, branched polyethylenimine, and casein. A multilevel statistical model was built to quantify if there was a significant difference in: a) extent of silver lost, b) initial amount of silver lost, c) silver lost for water of different quality, and d) total coliform removal. Experiments were performed on location at Pure Home Water, a CWF factory in Tamale, Ghana using stored rainwater and dugout water (a local surface water). The results indicated that using dugout vs. rainwater significantly affects the initial (p-value 0.0015) and sustained (p-value 0.0124) loss of silver, but that silver type does not have a significant effect. On average, dugout water removed 37.5μg/L more initial silver and had 1.1μg/L more silver in the filtrate than rainwater. Initially, filters achieved 1.9 log reduction values (LRVs) on average, but among different silver and water types this varied by as much as 2.5 LRV units. Overall, bacterial removal effectiveness was more challenging to evaluate, but some data suggest that the branched polyethylenimine silver nanoparticles provided improved initial bacterial removal over filters which were not painted with silver nanoparticles (p-value 0.038). Copyright © 2016 Elsevier B.V. All rights reserved.

A simplified genetic design for mammalian enamel

PubMed Central

Snead, ML; Zhu, D; Lei, YP; Luo, W; Bringas, P.; Sucov, H.; Rauth, RJ; Paine, ML; White, SN

2011-01-01

A biomimetic replacement for tooth enamel is urgently needed because dental caries is the most prevalent infectious disease to affect man. Here, design specifications for an enamel replacement material inspired by Nature are deployed for testing in an animal model. Using genetic engineering we created a simplified enamel protein matrix precursor where only one, rather than dozens of amelogenin isoforms, contributed to enamel formation. Enamel function and architecture were unaltered, but the balance between the competing materials properties of hardness and toughness was modulated. While the other amelogenin isoforms make a modest contribution to optimal biomechanical design, the enamel made with only one amelogenin isoform served as a functional substitute. Where enamel has been lost to caries or trauma a suitable biomimetic replacement material could be fabricated using only one amelogenin isoform, thereby simplifying the protein matrix parameters by one order of magnitude. PMID:21295848

Hydrologic data for the Big Spring basin, Clayton County, Iowa, water year 1990

USGS Publications Warehouse

Kalkhoff, Stephen J.; Kuzniar, R.L.; Kolpin, D.; Harvey, C.A.

1992-01-01

During a low-flow seepage study, May 29 and 30,1990, the measured discharge lost by streams in the basin was 8.56 cubic feet per second, the measured dissolved nitrogen load lost was 0.29 ton per day, and the measured atrazine load lost was 0.028 pound per day. The total measured discharge and total dissolved nitrogen load leaving the basin in streams were 3.63 cubic feet per second and about 0.04 ton per day, respectively.

Hydrologic data for the Big Spring basin, Clayton County, Iowa; water year 1989

USGS Publications Warehouse

Kalkhoff, S.J.; Kuzniar, R.L.

1991-01-01

During a baseflow seepage study, August 16 and 17, the measured discharge lost by streams in the basin was 2.82 cubic feet per second, the measured dissolved nitrogen load lost was 80 pounds per day, and the measured atrazine load lost was 0.002 pound per day. The total measured discharge and total dissolved nitrogen load leaving the basin in streams was 0.07 cubic feet per second and less than 20 pounds per day, respectively.

Plasma osmotic changes during major abdominal surgery.

PubMed

Malone, R A; McLeavey, C A; Arens, J F

1977-12-01

Fluid balance across the capillary membrane is maintained normally by a balance of hydrostatic and colloid osmotic pressures (COP). In 12 patients having major intra-abdominal procedures, the COP was followed during the operative and immediate postoperative periods. The patients' intraoperative fluid management consisted of replacing shed blood with blood and following Shires' concept of crystalloid replacement. Significant decreases in COP to approximately two thirds of the initial value occurred in patients having intra-abdominal procedures versus only a 10 percent decrease in those having peripheral procedures (greater than .001). As a result of this decrease in COP, the balance between hydrostatic and colloid osmotic pressures is lost and risk of pulmonary intersitial edema is increased.

Dental implants: A review.

PubMed

Guillaume, B

2016-12-01

A high number of patients have one or more missing tooth and it is estimated that one in four American subjects over the age of 74 have lost all their natural teeth. Many options exist to replace missing teeth but dental implants have become one of the most used biomaterial to replace one (or more) missing tooth over the last decades. Contemporary dental implants made with titanium have been proven safe and effective in large series of patients. This review considers the main historical facts concerned with dental implants and present the different critical factors that will ensure a good osseo-integration that will ensure a stable prosthesis anchorage. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

Factors influencing the restoration of fluid and electrolyte balance after exercise in the heat.

PubMed Central

Maughan, R J; Leiper, J B; Shirreffs, S M

1997-01-01

Maintenance of fluid balance is a major concern for all athletes competing in events held in hot climates. This paper reviews recent work relating to optimisation of fluid replacement after sweat loss induced by exercising in the heat. Data are taken from studies undertaken in our laboratory. Issues investigated were drink composition, volume consumed, effects of consuming food with a drink, effects of alcohol in rehydration effectiveness, voluntary intake of fluid, and considerations for women related to the menstrual cycle. The results are presented as a series of summaries of experiments, followed by a discussion of the implications. The focus of this review is urine output after ingestion of a drink; fluid excreted in urine counteracts rehydration. Also included are data on the restoration of plasma volume losses. Ingestion of large volumes of plain water will inhibit thirst and will also promote a diuretic response. If effective rehydration is to be maintained for some hours after fluid ingestion, drinks should contain moderately high levels of sodium (perhaps as much as 50-60 mmol/l) and possibly also some potassium to replace losses in the sweat. To surmount ongoing obligatory urine losses, the volume consumed should be greater than the volume of sweat lost. Palatability of drinks is important in stimulating intake and ensuring adequate volume replacement. Where opportunities allow, the electrolytes required may be ingested as solid food consumed with a drink. There are no special concerns for women related to changes in hormone levels associated with the menstrual cycle. Ingestion of carbohydrate-electrolyte drinks in the post-exercise period restores exercise capacity more effectively than plain water. The effects on performance of an uncorrected fluid deficit should persuade all athletes to attempt to remain fully hydrated at all times, and the aim should be to start each bout of exercise in a fluid replete state. This will only be achieved if a volume of fluid in excess of the sweat loss is ingested together with sufficient electrolytes. PMID:9298549

Arrow Lakes Reservoir Fertilization Experiment, Technical Report 1999-2004.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schindler, E.

2007-02-01

The Arrow Lakes food web has been influenced by several anthropogenic stressors during the past 45 years. These include the introduction of mysid shrimp (Mysis relicta) in 1968 and 1974 and the construction of large hydroelectric impoundments in 1969, 1973 and 1983. The construction of the impoundments affected the fish stocks in Upper and Lower Arrow lakes in several ways. The construction of Hugh Keenleyside Dam (1969) resulted in flooding that eliminated an estimated 30% of the available kokanee spawning habitat in Lower Arrow tributaries and at least 20% of spawning habitat in Upper Arrow tributaries. The Mica Dam (1973)more » contributed to water level fluctuations and blocked upstream migration of all fish species including kokanee. The Revelstoke Dam (1983) flooded 150 km of the mainstem Columbia River and 80 km of tributary streams which were used by kokanee, bull trout, rainbow trout and other species. The construction of upstream dams also resulted in nutrient retention which ultimately reduced reservoir productivity. In Arrow Lakes Reservoir (ALR), nutrients settled out in the Revelstoke and Mica reservoirs, resulting in decreased productivity, a process known as oligotrophication. Kokanee are typically the first species to respond to oligotrophication resulting from aging impoundments. To address the ultra-oligotrophic status of ALR, a bottom-up approach was taken with the addition of nutrients (nitrogen and phosphorus in the form of liquid fertilizer from 1999 to 2004). Two of the main objectives of the experiment were to replace lost nutrients as a result of upstream impoundments and restore productivity in Upper Arrow and to restore kokanee and other sport fish abundance in the reservoir. The bottom-up approach to restoring kokanee in ALR has been successful by replacing nutrients lost as a result of upstream impoundments and has successfully restored the productivity of Upper Arrow. Primary production rates increased, the phytoplankton community responded with a shift in species and zooplankton biomass was more favorable for kokanee. With more productive lower trophic levels, the kokanee population increased in abundance and biomass, resulting in improved conditions for bull trout, one of ALR's piscivorous species.« less

Bacterial contamination of drinking water and the economic burden of illnesses for the Nepalese households.

PubMed

Atreya, Kishor; Panthee, Santosh; Sharma, Prem

2006-10-01

A household survey was conducted to determine the number of working days lost and household medical expenditure (ME) due to six water-borne diseases in the Terai region of Nepal. Drinking water sources of each household were analysed for total coliforms (TC). The study found 61% of the household water sources were contaminated with TC at the time of sampling. Number of days lost due to water-borne diseases was 8 days for TC-negative households and 10 days for TC-positive households per year. The average annual household medical expenditure was NR 459 for TC-negative households, and NR 789 for TC-positive households (p = 0.02 at proportional to = 0.05). Regression result showed that the presence of TC in the drinking water sources, number of children in the household and income of the household significantly determined ME.

The management of heat stress for the firefighter: a review of work conducted on behalf of the Toronto Fire Service.

PubMed

McLellan, Tom M; Selkirk, Glen A

2006-07-01

This report provides a summary of research conducted through a grant provided by the Workplace Safety Insurance Board of Ontario. The research was divided into two phases; first, to define safe work limits for firefighters wearing their protective clothing and working in warm environments; and, the second, to examine strategies to reduce the thermal burden and extend the operational effectiveness of the firefighter. For the first phase, subjects wore their protective ensemble and carried their self-contained breathing apparatus (SCBA) and performed very light, light, moderate or heavy work at 25 degrees C, 30 degrees C or 35 degrees C. Thermal and evaporative resistance coefficients were obtained from thermal manikin testing that allowed the human physiological responses to be compared with modeled data. Predicted continuous work times were then generated using a heat strain model that established limits for increases in body temperature to 38.0 degrees C, 38.5 degrees C and 39.0 degrees C. Three experiments were conducted for the second phase of the project. The first study revealed that replacing the duty uniform pants that are worn under the bunker pants with shorts reduced the thermal strain for activities that lasted longer than 60 min. The second study examined the importance of fluid replacement. The data revealed that fluid replacement equivalent to at least 65% of the sweat lost increased exposure time by 15% compared with no fluid replacement. The last experiment compared active and passive cooling. Both the use of a mister or forearm and hand submersion in cool water significantly increased exposure time compared with passive cooling that involved only removing most of the protective clothing. Forearm and hand submersion proved to be most effective and produced dramatic increases in exposure time that approximated 65% compared with the passive cooling procedure. When the condition of no fluid replacement and passive cooling was compared with fluid replacement and forearm and hand submersion, exposure times were effectively doubled with the latter condition. The heat stress wheel that was generated can be used by Commanders to determine safe work limits for their firefighters during activities that involve wearing their protective clothing and carrying their SCBA.

Elevated soil nitrogen pools after conversion of turfgrass to water-efficient residential landscapes

NASA Astrophysics Data System (ADS)

Heavenrich, Hannah; Hall, Sharon J.

2016-08-01

As a result of uncertain resource availability and growing populations, city managers are implementing conservation plans that aim to provide services for people while reducing household resource use. For example, in the US, municipalities are incentivizing homeowners to replace their water-intensive turfgrass lawns with water-efficient landscapes consisting of interspersed drought-tolerant shrubs and trees with rock or mulch groundcover (e.g. xeriscapes, rain gardens, water-wise landscapes). While these strategies are likely to reduce water demand, the consequences for other ecosystem services are unclear. Previous studies in controlled, experimental landscapes have shown that conversion from turfgrass to shrubs may lead to high rates of nutrient leaching from soils. However, little is known about the long-term biogeochemical consequences of this increasingly common land cover change across diverse homeowner management practices. We explored the fate of soil nitrogen (N) across a chronosequence of land cover change from turfgrass to water-efficient landscapes in privately owned yards in metropolitan Phoenix, Arizona, in the arid US Southwest. Soil nitrate ({{{{NO}}}3}--N) pools were four times larger in water-efficient landscapes (25 ± 4 kg {{{{NO}}}3}--N/ha 0-45 cm depth) compared to turfgrass lawns (6 ± 7 kg {{{{NO}}}3}--N/ha). Soil {{{{NO}}}3}--N also varied significantly with time since landscape conversion; the largest pools occurred at 9-13 years after turfgrass removal and declined to levels comparable to turfgrass thereafter. Variation in soil {{{{NO}}}3}--N with landscape age was strongly influenced by management practices related to soil water availability, including shrub cover, sub-surface plastic sheeting, and irrigation frequency. Our findings show that transitioning from turfgrass to water-efficient residential landscaping can lead to an accumulation of {{{{NO}}}3}--N that may be lost from the plant rooting zone over time following irrigation or rainfall. These results have implications for best management practices to optimize the benefits of water-conserving landscapes while protecting water quality.

Urban outdoor water use and response to drought assessed through mobile energy balance and vegetation greenness measurements

USDA-ARS?s Scientific Manuscript database

Urban vegetation provides many highly valued ecosystem services but also requires extensive urban water resources. Increasingly, cities are experiencing water limitations and managing outdoor urban water use is an important concern. Quantifying the water lost via evapotranspiration (ET) is critical ...

Doubly labeled water method: in vivo oxygen and hydrogen isotope fractionation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schoeller, D.A.; Leitch, C.A.; Brown, C.

The accuracy and precision of the doubly labeled water method for measuring energy expenditure are influenced by isotope fractionation during evaporative water loss and CO/sub 2/ excretion. To characterize in vivo isotope fractionation, we collected and isotopically analyzed physiological fluids and gases. Breath and transcutaneous water vapor were isotopically fractionated. The degree of fractionation indicated that the former was fractionated under equilibrium control at 37/sup 0/C, and the latter was kinetically fractionated. Sweat and urine were unfractionated. By use of isotopic balance models, the fraction of water lost via fractionating routes was estimated from the isotopic abundances of body water,more » local drinking water, and dietary solids. Fractionated water loss averaged 23% (SD = 10%) of water turnover, which agreed with our previous estimates based on metabolic rate, but there was a systematic difference between the results based on O/sub 2/ and hydrogen. Corrections for isotopic fractionation of water lost in breath and (nonsweat) transcutaneous loss should be made when using labeled water to measure water turnover or CO/sub 2/ production.« less

Costs and prevention of patient defection.

PubMed

Clarke, R N

2001-01-01

Although other industries have recognized that increased customer loyalty brings increased revenues and profitability, few medical practices have sought even to measure patient retention or loyalty. When patients leave a practice, new patients must be attracted to replace lost ones at significant cost, often invisible to and underestimated by physicians. Understanding the lifetime value of a patient may be one route that leads to better patient loyalty practices and enhanced profitability.

The Loss of a Baby and the Birth of the Next Infant: The Mother's Experience

ERIC Educational Resources Information Center

Reid, Marguerite

2007-01-01

This paper considers the area of perinatal death by focusing on the mother's experience. An argument is made for questioning whether mothers attempt to replace a dead infant. It is suggested instead that they long to mother their lost baby and as a result their new infant is mothered in the shadow of the dead baby. The term "penumbra baby" is…

Searching for Partners: Regional Organizations and Peace Operations

DTIC Science & Technology

1998-06-01

directed force, the U.N. Protection Force (UNPROFOR), performed abysmally in Bosnia and had to be replaced by a combination of NATO and other forces...African regional organization. Other examplars were the operational support provided by NATO during the U.N. Protection Force (UNPROFOR) phase of...body capable of organizing or directing field operations. 34 Lewis a n d Marks Even in the realm of protecting human rights, OSCE has lost

Operator’s Manual. Prototype Heavy Rescue/Fire Fighting Vehicle

DTIC Science & Technology

1980-09-01

system for emergency operation if pressure is lost in either parking or service brake systems . The system is operational automatically and is...controlled by the foot treadle ’sive. It will provide for TWO full brake applications and ONE release. ELECTRICAL SYSTEM A dual battery system is utilized for...cleaner. * Lubricate chassis. . Repack wheel bearings. . Inspect brake system and adjust brakes . . Replace fuel filter. . Check high and low idle.

Survival, movement, and health of hatchery-raised juvenile Lost River suckers within a mesocosm in Upper Klamath Lake, Oregon

USGS Publications Warehouse

Hereford, Danielle M.; Burdick, Summer M.; Elliott, Diane G.; Dolan-Caret, Amari; Conway, Carla M.; Harris, Alta C.

2016-01-28

The recovery of endangered Lost River suckers (Deltistes luxatus) in Upper Klamath Lake is limited by poor juvenile survival and failure to recruit into the adult population. Poor water quality, degradation of rearing habitat, and toxic levels of microcystin are hypothesized to contribute to low juvenile survival. Studies of wild juvenile suckers are limited in that capture rates are low and compromised individuals are rarely captured in passive nets. The goal of this study was to assess the use of a mesocosm for learning about juvenile survival, movement, and health. Hatchery-raised juvenile Lost River suckers were PIT (passive integrated transponder) tagged and monitored by three vertically stratified antennas. Fish locations within the mesocosm were recorded at least every 30 minutes and were assessed in relation to vertically stratified water-quality conditions. Vertical movement patterns were analyzed to identify the timing of mortality for each fish. Most mortality occurred from July 28 to August 16, 2014. Juvenile suckers spent daylight hours near the benthos and moved throughout the entire water column during dark hours. Diel movements were not in response to dissolved-oxygen concentrations, temperature, or pH. Furthermore, low dissolved-oxygen concentrations, high temperatures, high pH, high un-ionized ammonia, or high microcystin levels did not directly cause mortality, although indirect effects may have occurred. However, water-quality conditions known to be lethal to juvenile Lost River suckers did not occur during the study period. Histological assessment revealed severe gill hyperplasia and Ichthyobodo sp. infestations in most moribund fish. For these fish, Ichthyobodo sp. was likely the cause of mortality, although it is unclear if this parasite originated in the rearing facility because fish were not screened for this parasite prior to introduction. This study has demonstrated that we can effectively use a mesocosm equipped with antennas to learn about the timing of mortality, movement, and health of PIT-tagged hatchery-raised juvenile Lost River suckers.

Floaters may buffer the extinction risk of small populations: an empirical assessment

PubMed Central

2017-01-01

The high extinction risk of small populations is commonly explained by reductions in fecundity and breeder survival associated with demographic and environmental stochasticity. However, ecological theory suggests that population extinctions may also arise from reductions in the number of floaters able to replace the lost breeders. This can be particularly plausible under harsh fragmentation scenarios, where species must survive as small populations subjected to severe effects of stochasticity. Using a woodpecker study in fragmented habitats (2004–2016), we provide here empirical support for the largely neglected hypothesis that floaters buffer population extirpation risks. After controlling for population size, patch size and the intrinsic quality of habitat, populations in patches with floaters had a lower extinction probability than populations in patches without floaters (0.013 versus 0.131). Floaters, which often replace the lost breeders, were less likely to occur in small and low-quality patches, showing that population extirpations may arise from unnoticed reductions in floater numbers in poor-quality habitats. We argue that adequate pools of the typically overlooked floaters may buffer extirpation risks by reducing the detrimental impacts of demographic and environmental stochasticity. However, unravelling the influence of floaters in buffering stochastic effects and promoting population stability require additional studies in an ample array of species and stochastic scenarios. PMID:28424345

Floaters may buffer the extinction risk of small populations: an empirical assessment.

PubMed

Robles, Hugo; Ciudad, Carlos

2017-04-26

The high extinction risk of small populations is commonly explained by reductions in fecundity and breeder survival associated with demographic and environmental stochasticity. However, ecological theory suggests that population extinctions may also arise from reductions in the number of floaters able to replace the lost breeders. This can be particularly plausible under harsh fragmentation scenarios, where species must survive as small populations subjected to severe effects of stochasticity. Using a woodpecker study in fragmented habitats (2004-2016), we provide here empirical support for the largely neglected hypothesis that floaters buffer population extirpation risks. After controlling for population size, patch size and the intrinsic quality of habitat, populations in patches with floaters had a lower extinction probability than populations in patches without floaters (0.013 versus 0.131). Floaters, which often replace the lost breeders, were less likely to occur in small and low-quality patches, showing that population extirpations may arise from unnoticed reductions in floater numbers in poor-quality habitats. We argue that adequate pools of the typically overlooked floaters may buffer extirpation risks by reducing the detrimental impacts of demographic and environmental stochasticity. However, unravelling the influence of floaters in buffering stochastic effects and promoting population stability require additional studies in an ample array of species and stochastic scenarios. © 2017 The Author(s).

The cost of insulin-dependent diabetes mellitus (IDDM) in England and Wales.

PubMed

Gray, A; Fenn, P; McGuire, A

1995-12-01

This study estimates the direct health and social care costs of insulin-dependent diabetes mellitus (IDDM) in England and Wales in 1992 to be 96 million pounds, or 1021 pounds per person in a population with IDDM estimated at 94,000 individuals. These costs include insulin maintenance, hospitalization, GP and out-patient consultations, renal replacement therapy, and payments to informal carers. Expenditure is concentrated on younger age groups, with one-third of the total expended on those aged 0-24. Around one-half of the total costs can be directly attributed to IDDM, with the remainder associated with a range of complications of the disease. The single largest area of service expenditure is renal replacement therapy. The cost estimates are most sensitive to incidence rates of IDDM, numbers on dialysis and average duration of dialysis. A further 113 million pounds may be lost each year due to premature deaths resulting in lost productive contributions to the economy. The direct and indirect costs of IDDM are therefore significant. The cost of illness framework presented here should facilitate the economic evaluation of new and existing treatment regimens, which may improve value for money by reducing costs and/or increasing the quality or quantity of life for people with IDDM.

Analysis of Outcomes of the Nutritional Status in Patients Qualified for Aortic Valve Replacement in Comparison to Healthy Elderly

PubMed Central

Jagielak, Dariusz; Dardzińska, Jolanta Anna; Aleksandrowicz-Wrona, Ewa; Rogowski, Jan; Gruszecka, Agnieszka; Małgorzewicz, Sylwia

2018-01-01

Severe aortic stenosis (AS) is associated with the reduction of muscle mass and may be associated with deterioration of nutritional status. Furthermore, malnourished cardiac patients are characterized by a higher risk of postoperative complications and mortality. The aim of this study was the evaluation and comparison of nutritional status, appetite and body composition in older people with severe aortic stenosis before aortic valve replacement and healthy elderly volunteers. One hundred and one patients, aged >65 years old with severe AS were included in the study. Nutritional status was assessed. Body composition was estimated using bioelectrical impedance analysis. Concentrations of albumin, prealbumin, triglycerides, total cholesterol and C-reactive protein were measured, and a complete blood count was done. About 40% of AS patients were at risk of malnutrition. They had decreased hand grip strength and they lost more body mass than the control group. Malnourished AS patients were older, had lower body mass indexes (BMIs) and lower aortic valve areas in comparison to well-nourished patients. Older AS patients, like their peers, show excessive body mass and, at the same time, the features of malnutrition. They have additional factors such as unintentional weight lost and decreased muscle strength which may be associated with worse outcomes. PMID:29510548

Waterborne outbreak of gastroenteritis: effects on sick leaves and cost of lost workdays.

PubMed

Halonen, Jaana I; Kivimäki, Mika; Oksanen, Tuula; Virtanen, Pekka; Virtanen, Mikko J; Pentti, Jaana; Vahtera, Jussi

2012-01-01

In 2007, part of a drinking water distribution system was accidentally contaminated with waste water effluent causing a gastroenteritis outbreak in a Finnish town. We examined the acute and cumulative effects of this incidence on sick leaves among public sector employees residing in the clean and contaminated areas, and the additional costs of lost workdays due to the incidence. Daily information on sick leaves of 1789 Finnish Public Sector Study participants was obtained from employers' registers. Global Positioning System-coordinates were used for linking participants to the clean and contaminated areas. Prevalence ratios (PR) for weekly sickness absences were calculated using binomial regression analysis. Calculations for the costs were based on prior studies. Among those living in the contaminated areas, the prevalence of participants on sick leave was 3.54 (95% confidence interval (CI) 2.97-4.22) times higher on the week following the incidence compared to the reference period. Those living and working in the clean area were basically not affected, the corresponding PR for sick leaves was 1.12, 95% CI 0.73-1.73. No cumulative effects on sick leaves were observed among the exposed. The estimated additional costs of lost workdays due to the incidence were 1.8-2.1 million euros. The prevalence of sickness absences among public sector employees residing in affected areas increased shortly after drinking water distribution system was contaminated, but no long-term effects were observed. The estimated costs of lost workdays were remarkable, thus, the cost-benefits of better monitoring systems for the water distribution systems should be evaluated.

Replacement predictions for drinking water networks through historical data.

PubMed

Malm, Annika; Ljunggren, Olle; Bergstedt, Olof; Pettersson, Thomas J R; Morrison, Gregory M

2012-05-01

Lifetime distribution functions and current network age data can be combined to provide an assessment of the future replacement needs for drinking water distribution networks. Reliable lifetime predictions are limited by a lack of understanding of deterioration processes for different pipe materials under varied conditions. An alternative approach is the use of real historical data for replacement over an extended time series. In this paper, future replacement needs are predicted through historical data representing more than one hundred years of drinking water pipe replacement in Gothenburg, Sweden. The verified data fits well with commonly used lifetime distribution curves. Predictions for the future are discussed in the context of path dependence theory. Copyright © 2012 Elsevier Ltd. All rights reserved.

Nicotine-substitute gum-induced milk alkali syndrome: a look at unexpected sources of calcium.

PubMed

Swanson, Christine M; Mackey, Patricia A; Westphal, Sydney A; Argueta, Rodolfo

2013-01-01

This report describes a 64-year-old woman with recurrent hypercalcemia. Her laboratory evaluation was consistent with milk-alkali syndrome. It was eventually discovered that the source of the excessive calcium consumption was nicotine-replacement chewing gum and carbonated water. An extensive literature search was performed to see if milk-alkali syndrome due to nicotine-replacement gum and carbonated water has been previously reported. No prior report describing the association of milk alkali syndrome with nicotine-replacement gum and carbonated water was found. We present a unique case of milk-alkali syndrome due to nicotine-replacement gum and carbonated water. It serves as a lesson to evaluate other sources besides calcium supplements as the cause of excessive calcium intake.

Water--Problems and Solutions. A Report Concerning the Problems and Solutions of Negative Water Balance.

ERIC Educational Resources Information Center

Ewert, Alan

Outdoor leaders constantly face problems created by water shortage and, to act effectively, must thoroughly understand the body's use of water and the ways to delay dehydration when water shortage occurs. Dehydration begins when there is a negative water balance, or more water lost than ingested, and progresses from the stage of dryness, to the…

Water sources and controls on water-loss rates of epigeous ectomycorrhizal fungal sporocarps during summer drought

Treesearch

Erik A. Lilleskov; Thomas D. Bruns; Todd E. Dawson; Francisco J. Camacho

2009-01-01

Access to deeper soil water and water-conserving traits should reduce water stress for ectomycorrhizal fungi, permitting function during drought. Here, we explored whether epigeous fruiting of ectomycorrhizal fungi during drought was facilitated by access to deep soil water, how much water was lost from sporocarps, and how sporocarp surface to volume ratios affected...

Iodine-129 in the Snake River Plain aquifer at the Idaho National Engineering Laboratory, Idaho

USGS Publications Warehouse

Mann, L.J.; Chew, E.W.; Morton, J.S.; Randolph, R.B.

1988-01-01

From 1953 to 1983, an estimated 0.01 to 0.136 Ci (curies)/year of iodine-129 were contained in wastewater generated by the ICPP (Idaho Chemical Processing Plant) at the Idaho National Engineering Laboratory. The wastewater was directly discharged to the Snake River Plain aquifer through a deep disposal well until February 9, 1984, when the well was replaced by an unlined infiltration pond; a second pond was put into use on October 17, 1985. For 1984-86, the annual amount of iodine-129 in wastewater discharged to the ponds ranged from 0.0064 to 0.039 Ci. In August 1986, iodine-129 concentrations in water from 35 wells near the ICPP ranged from less than the reporting level to 3.6 +or-0.4 pCi/L (picocuries/L). By comparison, in April 1977 the water from 20 wells contained a maximum of 27 +or-1 pCi/L of iodine-129; in 1981, the maximum concentration in water from 32 wells was 41 +or-2 pCi/L. The average concentrations of iodine-129 in water from 18 wells that were sampled in 1977, 1981 and 1986 were 4.0, 6.7 and 1.3 pCi/L, respectively. The marked decrease in the iodine-129 concentration from 1981 to 1986 is the result of three factors: (1) The amount of iodine-129 disposed annually; (2) a change from the routine use of the disposal well to the infiltration ponds; and (3) a dilution of the iodine-129 in the aquifer by recharge from the Big Lost River. (USGS)

Design and Manufacture of Wood Blades for Windtunnel Fans

NASA Technical Reports Server (NTRS)

Richardson, S. E.

1998-01-01

Many windtunnels use wooden fan blades, however, because of their usual long life (often in excess of 50 years) wooden blades typically do not have to be replaced very often; therefore, the expertise for designing and building wooden windtunnel fan blades is being lost. The purpose of this report is to document the design and build process so that when replacement blades are eventually required some of the critical information required is available. Information useful to fan-blade designers, fabricators, inspectors, and windtunnel operations personnel is included. Fixed pitch and variable pitch fans as well as fans which range in size from a few feet in diameter to over 40 ft. in diameter are described. Woods, adhesives, and coverings are discussed.

Muon radiolysis affected by density inhomogeneity in near-critical fluids.

PubMed

Cormier, P J; Alcorn, C; Legate, G; Ghandi, K

2014-04-01

In this article we show the significant tunability of radiation chemistry in supercritical ethane and to a lesser extent in near critical CO2. The information was obtained by studies of muonium (Mu = μ(+)e(-)), which is formed by the thermalization of positive muons in different materials. The studies of the proportions of three fractions of muon polarization, PMu, diamagnetic PD and lost fraction, PL provided the information on radiolysis processes involved in muon thermalization. Our studies include three different supercritical fluids, water, ethane and carbon dioxide. A combination of mobile electrons and other radiolysis products such as (•)C2H5 contribute to interesting behavior at densities ∼40% above the critical point in ethane. In carbon dioxide, an increase in electron mobility contributes to the lost fraction. The hydrated electron in water is responsible for the lost fraction and decreases the muonium fraction.

Simulated reductions in consumption of sugar-sweetened beverages improves dietary in Lower Mississippi Delta adults

USDA-ARS?s Scientific Manuscript database

While the effects of replacing sugar-sweetened beverages with water on energy intake and body weight have been reported, little is known about how these replacements affect diet quality. We simulated the effects of replacing sugar-sweetened beverages with tap water on the diet quality of Lower Miss...

Common developmental pathways link tooth shape to regeneration

PubMed Central

Fraser, Gareth J.; Bloomquist, Ryan F.; Streelman, J. Todd

2013-01-01

In many non-mammalian vertebrates, adult dentitions result from cyclical rounds of tooth regeneration wherein simple unicuspid teeth are replaced by more complex forms. Therefore and by contrast to mammalian models, the numerical majority of vertebrate teeth develop shape during the process of replacement. Here, we exploit the dental diversity of Lake Malawi cichlid fishes to ask how vertebrates generally replace their dentition and in turn how this process acts to influence resulting tooth morphologies. First, we used immunohistochemistry to chart organogenesis of continually replacing cichlid teeth and discovered an epithelial down-growth that initiates the replacement cycle via a labial proliferation bias. Next, we identified sets of co-expressed genes from common pathways active during de novo, lifelong tooth replacement and tooth morphogenesis. Of note, we found two distinct epithelial cell populations, expressing markers of dental competence and cell potency, which may be responsible for tooth regeneration. Related gene sets were simultaneously active in putative signaling centers associated with the differentiation of replacement teeth with complex shapes. Finally, we manipulated targeted pathways (BMP, FGF, Hh, Notch, Wnt/β-catenin) in vivo with small molecules and demonstrated dose-dependent effects on both tooth replacement and tooth shape. Our data suggest that the processes of tooth regeneration and tooth shape morphogenesis are integrated via a common set of molecular signals. This linkage has subsequently been lost or decoupled in mammalian dentitions where complex tooth shapes develop in first generation dentitions that lack the capacity for lifelong replacement. Our dissection of the molecular mechanics of vertebrate tooth replacement coupled to complex shape pinpoints aspects of odontogenesis that might be re-evolved in the lab to solve problems in regenerative dentistry. PMID:23422830

An experimental summary of plasma arc exposures of space shuttle high-temperature reusable surface insulation tile array with a single missing tile (conducted at the Ames Research Center)

NASA Technical Reports Server (NTRS)

Galanter, S. A.

1975-01-01

A space shuttle high temperature reusable surface insulation (HRSI) tile array with a single missing or lost tile was exposed to a hot gas simulated reentry environment to investigate the heating conditions in and around the vicinity of the missing HRSI tile. Heat flux and pressure data for the lost tile condition were obtained by the use of a water cooled lost tile calibration model. The maximum aluminum substrate temperature obtained during the simulated reentry was 128 C (263 F). The lost tile calibration data indicated a maximum heat flux in the lost tile cavity region of 63 percent of the upstream reference value. This test was conducted at the Ames Research Center in the 20 MW semielliptical thermal protection system (TPS) pilot plasma arc test facility.

Multilevel groundwater monitoring of hydraulic head and temperature in the eastern Snake River Plain aquifer, Idaho National Laboratory, Idaho, 2011-13

USGS Publications Warehouse

Twining, Brian V.; Fisher, Jason C.

2015-01-01

Normalized mean head values were analyzed for all 11 multilevel monitoring wells for the period of record (2007–13). The mean head values suggest a moderately positive correlation among all boreholes and generally reflect regional fluctuations in water levels in response to seasonal climatic changes. Boreholes within volcanic rift zones and near the southern boundary (USGS 103, USGS 105, USGS 108, USGS 132, USGS 135, USGS 137A) display a temporal correlation that is strongly positive. Boreholes in the Big Lost Trough display some variations in temporal correlations that may result from proximity to the mountain front to the northwest and episodic flow in the Big Lost River drainage system. For example, during June 2012, boreholes MIDDLE 2050A and MIDDLE 2051 showed head buildup within the upper zones when compared to the June 2010 profile event, which correlates to years when surface water was reported for the Big Lost River several months preceding the measurement period. With the exception of borehole USGS 134, temporal correlation between MLMS wells completed within the Big Lost Trough is generally positive. Temporal correlation for borehole USGS 134 shows the least agreement with other MLMS boreholes located within the Big Lost Trough; however, borehole USGS 134 is close to the mountain front where tributary valley subsurface inflow is suspected.

Measured and simulated soil water evaporation from four Great Plains soils

USDA-ARS?s Scientific Manuscript database

The amount of soil water lost during stage one and stage two soil water evaporation is of interest to crop water use modelers. The ratio of measured soil surface temperature (Ts) to air temperature (Ta) was tested as a signal for the transition in soil water evaporation from stage one to stage two d...

The effect of monsoon variability on fish landing in the Sadeng Fishing Port of Yogyakarta, Indonesia

NASA Astrophysics Data System (ADS)

Subarna, D.

2018-03-01

The volume of landing fish of the Sadeng Fishing Port within certain months showed an increase from year to year, especially during June, July and August (JJA). While in other months the fish production was low. The purpose of this research was to understand the influence of monsoon variability on fish landing in the Sadeng Fishing Port. Data were analyzed descriptively as spatial and temporal catch. Data were namely catch fish production collected from fishing port, while satellite and HYCOM model during 2011–2012 period were selected. The wind data, sea surface temperature (SST) and chlorophyll-a were analyzed from ASCAT and MODIS sensors during the Southeast Monsoon. The result showed the wind from the southeasterly provide wind stress at sea level and caused Ekman Transport to move away water mass from the sea shore. The lost water mass in the ocean surface was replaced by cold water from deeper layer which was rich in nutrients. The distribution of chlorophyll-a during the Southeast Monsoon was relatively higher in the southern coast of Java than during the Northwest monsoon. The SST showed approximately 25.3 °C. The abundance of nutrients indicated by the distribution of chlorophyll-a around the coast during the Southeast Monsoon, will enhance the arrival of larger fish. Thus, it can be understood that during June, July, and August the catch production is higher than the other months.

Strategic Dissonance: British Middle East Command in World War II

DTIC Science & Technology

2014-05-22

shipping in the Atlantic Ocean, slowing American replacement of the equipment lost at Dunkirk .4 In the overseas empire, nationalist movements in the...British soldiers were rescued from Greece, they were forced to abandon their equipment just as they had at Dunkirk less than a year earlier.19 Crete fell...at Dunkirk only 10 months earlier, the hasty withdrawl required abandoning aircraft, tanks, trucks, and artillery that were increasingly scarce.62

Internal Prosthetic Replacement of Skeletal Segments Lost in Combat Injuries.

DTIC Science & Technology

1973-08-31

osteo- articular bone grafts. Clin. Ortho., 87: 156, 1972. 8. Tuli, S. M.: Bridging of bone defects by massive bone grafts in tumorous conditions. Clin...fashion in its proximal one-third to "prevent distractic ,n of the fragments. The fiber metal segment was then placed in the appropriate defect and the...defect slightly oversized and also osteotomizing the fibula to delete any possible distracting forces or angulating forces. The only complication in

Linking Plant Water-Use Efficiency and Depth of Water Uptake to Field­-Level Productivity Under Surplus and Deficit Irrigation in Almond Orchards

NASA Astrophysics Data System (ADS)

Seely, T.; Shackel, K.; Silva, L. C. R.

2016-12-01

The impact of water stress on depth of water uptake, as well as water­-use efficiency (WUE) at the tree-level and field-level was examined in almond orchards under varying degrees of deficit and surplus irrigation treatments. Three different orchards, spanning a latitudinal gradient (35° to 39° N) were sampled during two growing seasons in the central valley of CA. The orchards encompass a range of climatic and edaphic conditions, providing an opportunity for comparisons of WUE and orchard yield under contrasting environmental conditions. In each orchard, the control treatment received 100% replacement of water lost to evapotranspiration (ET), while the surplus treatment received 110% and the deficit treatment received 70% replenishment of ET, the latter simulating conditions of water stress. Preliminary results based on the analysis of carbon isotope ratios (δ13C) in leaves throughout the 2015 and 2016 growing seasons, reveal a significant change in WUE in all three orchard sites, increasing up to 20% on average in the deficit irrigation treatment relative to controls. In contrast, trees growing under surplus irrigation had the lowest WUE across all orchard sites. The difference in WUE between surplus irrigated trees and control irrigated trees within each orchard was not always statistically significant. These physiological responses to levels of water availability were not reflected in field-level orchard productivity, which was highly variable across orchard sites and treatments. Additionally, analysis of oxygen (δ18O) and hydrogen (δ2H) isotope ratios of stem, leaf, and soil water has been undertaken to determine the effect of water stress on the depth of root water uptake. The hypothesis that almond trees can effectively acclimate to water stress through higher WUE and deeper root water uptake compared to well-watered trees will be tested. This multi-scale, ecohydrological study will elucidate the impacts of drought on almond orchards, one of the most water-intensive crops in California, as well as other tree­-dominated systems.

Soil Water Sensing-Focus on Variable Rate Irrigation

USDA-ARS?s Scientific Manuscript database

Irrigation scheduling using soil water sensors is an exercise in maintaining the water content of the crop root zone soil above a lower limit defined by the management allowed depletion (MAD) for that soil and crop, but not so wet that too much water is lost to deep percolation. The management allow...

Reestablishment of Native Riparian Species at an Altered High Elevation Site

Treesearch

Franklin J. Chan; Raymond W. Wong

1989-01-01

The failure of a 22-foot-diameter pipe caused an estimated water flow of 40,000 cfs for approximately one hour, which scoured and removed 1.75 million cubic yards of soil and vegetation from Lost Canyon. Mitigation for the damage caused by the pipe failure included reestablishing the lost vegetation. This paper describes the process of reestablishment including the...

Water, bound and mobile

EPA Science Inventory

Resolving the global transpiration flux is critical to constraining global carbon cycle models because carbon uptake by photosynthesis in terrestrial plants (Gross Primary Productivity, GPP) is directly related to water lost through transpiration. Quantifying GPP globally is cha...

Replacing fallow with continuous cropping reduces crop water productivity of semiarid wheat

USDA-ARS?s Scientific Manuscript database

Water supply frequently limits crop yield in semiarid cropping systems; water deficits can restrict yields in drought-affected subhumid regions. In semiarid wheat (Triticum aestivumL.)-based cropping systems, replacing an uncropped fallow period with a crop can increase precipitation use efficiency ...

Ultrasonic acoustic emissions from the sapwood of cedar and hemlock : an examination of three hypotheses regarding cavitations.

PubMed

Tyree, M T; Dixon, M A; Tyree, E L; Johnson, R

1984-08-01

Measurements are reported of ultrasonic acoustic emissions (AEs) measured from sapwood samples of Thuja occidentalis L. and Tsuga canadensis (L.) Carr. during air dehydration. The measurements were undertaken to test the following three hypotheses: (a) Each cavitation event produces one ultrasonic AE. (b) Large tracheids are more likely to cavitate than small tracheids. (c) When stem water potentials are >-0.4 MPa, a significant fraction of the water content of sapwood is held by ;capillary forces.' The last two hypotheses were recently discussed at length by M. H. Zimmermann. Experimental evidence consistent with all three hypotheses was obtained. The evidence for each hypothesis respectively is: (a) the cumulative number of AEs nearly equals the number of tracheids in small samples; (b) more water is lost per AE event at the beginning of the dehydration process than at the end, and (c) sapwood samples dehydrated from an initial water potential of 0 MPa lost significantly more water before AEs started than lost by samples dehydrated from an initial water potential of about -0.4 MPa. The extra water held by fully hydrated sapwood samples may have been capillary water as defined by Zimmerman.We also report an improved method for the measurement of the ;intensity' of ultrasonic AEs. Intensity is defined here as the area under the positive spikes of the AE signal (plotted as voltage versus time). This method was applied to produce a frequency histogram of the number of AEs versus intensity. A large fraction of the total number of AEs were of low intensity even in small samples (4 mm diameter by 10 mm length). This suggests that the effective ;listening distance' for most AEs was less than 5 to 10 mm.

Ultrasonic Acoustic Emissions from the Sapwood of Cedar and Hemlock 1

PubMed Central

Tyree, Melvin T.; Dixon, Michael A.; Tyree, E. Loeta; Johnson, Robert

1984-01-01

Measurements are reported of ultrasonic acoustic emissions (AEs) measured from sapwood samples of Thuja occidentalis L. and Tsuga canadensis (L.) Carr. during air dehydration. The measurements were undertaken to test the following three hypotheses: (a) Each cavitation event produces one ultrasonic AE. (b) Large tracheids are more likely to cavitate than small tracheids. (c) When stem water potentials are >−0.4 MPa, a significant fraction of the water content of sapwood is held by `capillary forces.' The last two hypotheses were recently discussed at length by M. H. Zimmermann. Experimental evidence consistent with all three hypotheses was obtained. The evidence for each hypothesis respectively is: (a) the cumulative number of AEs nearly equals the number of tracheids in small samples; (b) more water is lost per AE event at the beginning of the dehydration process than at the end, and (c) sapwood samples dehydrated from an initial water potential of 0 MPa lost significantly more water before AEs started than lost by samples dehydrated from an initial water potential of about −0.4 MPa. The extra water held by fully hydrated sapwood samples may have been capillary water as defined by Zimmerman. We also report an improved method for the measurement of the `intensity' of ultrasonic AEs. Intensity is defined here as the area under the positive spikes of the AE signal (plotted as voltage versus time). This method was applied to produce a frequency histogram of the number of AEs versus intensity. A large fraction of the total number of AEs were of low intensity even in small samples (4 mm diameter by 10 mm length). This suggests that the effective `listening distance' for most AEs was less than 5 to 10 mm. PMID:16663774

Competitive formation of b(2) and c(2)-H2O ions from b(3) ions containing Asp residue during tandem mass spectrometry: the influence of neighboring Arg.

PubMed

Guo, Mengzhe; Guo, Cheng; Pan, Yuanjiang

2014-08-01

The fragmentation of b3 ions derived from protonated Arg-Xxx-Asp-Ala-Ala (Xxx = Ala, Asp, Glu, Cys) and Arg-Xxx-Glu-Ala-Ala was investigated by electrospray ionization tandem mass spectrometry (MS (n) ) with collision-induced dissociation. A particular ion, which is 1 Da less than b2 ion, is shown to be the c2-H2O ion. The mechanism for its formation involved the aspartic acid in the third position easily losing anhydride to form a c2 ion, which then lost water to form an eight-membered ring of azacyclooctane derivative under the participation of the guanidine of the N-terminal arginine. However, this phenomenon was not observed when the aspartic acid was replaced by glutamic acid. The Amber program was used to determine the conformation of the original c2 residue from the dynamic energy perspective, and then density functional theory-based calculations and changing N-terminal amino acid from arginine to phenylalanine supported this mechanism.

Fine tuning of coenzyme specificity in family 2 aldo-keto reductases revealed by crystal structures of the Lys-274 → Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD + and NADP +

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leitgeb, Stefan; Petschacher, Barbara; Wilson, David K.

2005-01-11

Aldo-keto reductases of family 2 employ single site replacement Lys → Arg to switch their cosubstrate preference from NADPH to NADH. X-ray crystal structures of Lys-274 → Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD + and NADP + were determined at a resolution of 2.4 and 2.3 Å, respectively. Due to steric conflicts in the NADP +-bound form, the arginine side chain must rotate away from the position of the original lysine side chain, thereby disrupting a network of direct and water-mediated interactions between Glu-227, Lys-274 and the cofactor 2'-phosphate and 3'-hydroxy groups. Because anchoring contactsmore » of its Glu-227 are lost, the coenzyme-enfolding loop that becomes ordered upon binding of NAD(P) + in the wild-type remains partly disordered in the NADP +-bound mutant. The results delineate a catalytic reaction profile for the mutant in comparison to wild-type.« less

Some observations on the greenhouse effect at the Earth's surface.

PubMed

Akitt, J W

2018-01-05

It is shown that the greenhouse gases carbon dioxide and water vapour reflect back to the surface, all IR radiation originating at the surface within their respective spectral bands. This reflection occurs in a very thin layer at the surface, not much over 12cm in thickness. Heat is lost from the surface by heat exchange with the atmosphere and by loss of radiation. About 52% of radiation leaves the surface in two principal window regions but this is not enough to account for the earth's equilibrium temperature. This window radiation seems to disappear quite quickly and is replaced by black body radiation. It is this which eventually contributes to the earth's radiation balance, and has to originate approximately between 40 and 50km altitude where the temperature is about correct, near 255K. Doubling the CO 2 concentration increases the surface temperature by about 0.9°C and this need not have any influence higher up in the atmosphere. The surface temperature seems indeed to have no direct influence on the earth's external radiation balance. Copyright © 2017 Elsevier B.V. All rights reserved.

Lost, a desert river and its native fishes: A historical perspective of the lower Colorado River

USGS Publications Warehouse

Mueller, Gordon A.; Marsh, Paul C.

2002-01-01

The Colorado River had one of the most unique fish communities in the world. Seventy-five percent of those species were found no where else in the world. Settlement of the lower basin brought dramatic changes to both the river and its native fish. Those changes began more than 120 years ago as settlers began stocking nonnative fishes. By 1930, nonnative fish had spread throughout the lower basin and replaced native communities. All resemblance of historic river conditions faded with the construction of Hoover Dam in 1935 and other large water development projects. Today, few remember what the Colorado River was really like. Seven of the nine mainstream fishes are now federally protected as endangered. Federal and state agencies are attempting to recover these fish; however, progress has been frustrated due to the severity of human impact. This report presents testimony, old descriptions, and photographs describing the changes that have taken place in hopes that it will provide managers, biologists, and the interested public a better appreciation of the environment that shaped these unique fish.

Some observations on the greenhouse effect at the Earth's surface

NASA Astrophysics Data System (ADS)

Akitt, J. W.

2018-01-01

It is shown that the greenhouse gases carbon dioxide and water vapour reflect back to the surface, all IR radiation originating at the surface within their respective spectral bands. This reflection occurs in a very thin layer at the surface, not much over 12 cm in thickness. Heat is lost from the surface by heat exchange with the atmosphere and by loss of radiation. About 52% of radiation leaves the surface in two principal window regions but this is not enough to account for the earth's equilibrium temperature. This window radiation seems to disappear quite quickly and is replaced by black body radiation. It is this which eventually contributes to the earth's radiation balance, and has to originate approximately between 40 and 50 km altitude where the temperature is about correct, near 255 K. Doubling the CO2 concentration increases the surface temperature by about 0.9 °C and this need not have any influence higher up in the atmosphere. The surface temperature seems indeed to have no direct influence on the earth's external radiation balance.

Autotransplantation of a maxillary third molar to replace a maxillary premolar with vertical root fracture.

PubMed

Tsurumachi, T; Kakehashi, Y

2007-12-01

To report the successful autotransplantation of a fully developed third molar that required nonsurgical and surgical interventions for tooth adaptation. This case report describes the autotransplantation of a third molar with complete root development after the loss of a fractured premolar in a 47-year-old male. To allow better adaptation of the donor tooth, the buccal roots of the third molar were removed using a diamond bur and the canal entrances were filled. Recall examination 6 years after completion of root-canal treatment showed normal periodontal healing with absence of infection, ankylosis or progressive resorption. The transplantation of a third molar is seen as a promising method to replace a lost permanent tooth, and to restore aesthetics and function. *Autotransplantation is a viable option for the treatment of a missing tooth or for replacement of traumatized tooth when there is a donor tooth available. *Fully developed third molars are potentially reliable candidates in the absence of other suitable donor teeth.

Autogenous transplantation of mandibular third molar to replace tooth with vertical root fracture

PubMed Central

Asgary, Saeed

2009-01-01

Autogenous tooth transplantation (ATT) can be considered when there is a hopeless molar tooth and suitable donor present. This report presents an unconventional case of successful ATT of a third molar replacing the adjacent fractured second molar in a 33 year old woman. This wisdom tooth had completely developed roots. Root-end filling with Calcium Enriched Mixture (CEM) cement was performed in the third molar. The second molar was extracted non-traumatically without any bone removal; the wisdom tooth was immediately transplanted into the recipient socket. No endodontic treatment was carried out either during or after the ATT. At six-month and 2-year clinical examination the patient was asymptomatic; the transplanted tooth was still functional, with no evidence of marginal periodontal pathosis. At the same follow ups, radiographic evaluation illustrated bone regeneration, normal PDL, and absence of external root resorption. Transplantation of mature third molar seems to be a promising method for replacing a lost permanent molar tooth and restoring aesthetics and function. PMID:24003333

Comparison of corrosion scales in full and partially replaced lead service lines after changes in water quality

EPA Science Inventory

Preliminary results from scales formed 38 weeks following the LSL replacement simulations revealed differences in scale formations amongst varying water qualities and pipe sequence. Rigs fed with dechlorinated tap water show distinct pH gradients between the galvanic and the back...

The Pliocene Lost River found to west: Detrital zircon evidence of drainage disruption along a subsiding hotspot track

USGS Publications Warehouse

Hodges, M.K.V.; Link, P.K.; Fanning, C.M.

2009-01-01

SHRIMP analysis of U/Pb ages of detrital zircons in twelve late Miocene to Pleistocene sand samples from six drill cores on the Snake River Plain (SRP), Idaho, suggests that an ancestral Lost River system was drained westward along the northern side of the SRP. Neoproterozoic (650 to 740??Ma, Cryogenian) detrital zircon grains from the Wildhorse Creek drainage of the Pioneer Mountains core complex, with a source in 695??Ma orthogneiss, and which are characteristic of the Big Lost River system, are found in Pliocene sand from cores drilled in the central SRP (near Wendell) and western SRP (at Mountain Home). In addition to these Neoproterozoic grains, fluvial sands sourced from the northern margin of the SRP contain detrital zircons with the following ages: 42 to 52??Ma from the Challis magmatic belt, 80 to 100??Ma from the Atlanta lobe of the Idaho batholith, and mixed Paleozoic and Proterozoic ages (1400 to 2000??Ma). In contrast, sands in the Mountain Home Air Base well (MHAB) that contain 155-Ma Jurassic detrital grains with a source in northern Nevada are interpreted to represent an integrated Snake River, with provenance on the southern, eastern and northern sides of the SRP. We propose that late Pliocene and early Pleistocene construction of basaltic volcanoes and rhyolitic domes of the Axial Volcanic Zone of the eastern SRP and the northwest-trending Arco Volcanic Rift Zone (including the Craters of the Moon volcanic center), disrupted the paleo-Lost River drainage, confining it to the Big Lost Trough, a volcanically dammed basin of internal drainage on the Idaho National Laboratory (INL). After the Axial Volcanic Zone and Arco Volcanic Rift Zone were constructed to form a volcanic eruptive and intrusive highland to the southwest, sediment from the Big Lost River was trapped in the Big Lost Trough instead of being delivered by surface streams to the western SRP. Today, water from drainages north of the SRP enters the Snake River Plain regional aquifer through sinks in the Big Lost Trough, and the water resurfaces at Thousand Springs, Idaho, about 195??km to the southwest. Holocene to latest Pliocene samples from drill core in the Big Lost Trough reveal interplay between the glacio-fluvial outwash of the voluminous Big Lost River system and the relatively minor Little Lost River system. A mixed provenance signature is recognized in fine-grained sands deposited in a highstand of a Pleistocene pluvial-lake system. ?? 2009 Elsevier B.V.

Prediction of plant vulnerability to salinity increase in a coastal ecosystem by stable isotopic composition (δ18O) of plant stem water: a model study

USGS Publications Warehouse

Zhai, Lu; Jiang, Jiang; DeAngelis, Donald L.; Sternberg, Leonel d.S.L

2016-01-01

Sea level rise and the subsequent intrusion of saline seawater can result in an increase in soil salinity, and potentially cause coastal salinity-intolerant vegetation (for example, hardwood hammocks or pines) to be replaced by salinity-tolerant vegetation (for example, mangroves or salt marshes). Although the vegetation shifts can be easily monitored by satellite imagery, it is hard to predict a particular area or even a particular tree that is vulnerable to such a shift. To find an appropriate indicator for the potential vegetation shift, we incorporated stable isotope 18O abundance as a tracer in various hydrologic components (for example, vadose zone, water table) in a previously published model describing ecosystem shifts between hammock and mangrove communities in southern Florida. Our simulations showed that (1) there was a linear relationship between salinity and the δ18O value in the water table, whereas this relationship was curvilinear in the vadose zone; (2) hammock trees with higher probability of being replaced by mangroves had higher δ18O values of plant stem water, and this difference could be detected 2 years before the trees reached a tipping point, beyond which future replacement became certain; and (3) individuals that were eventually replaced by mangroves from the hammock tree population with a 50% replacement probability had higher stem water δ18O values 3 years before their replacement became certain compared to those from the same population which were not replaced. Overall, these simulation results suggest that it is promising to track the yearly δ18O values of plant stem water in hammock forests to predict impending salinity stress and mortality.

Soil water sensing: Implications of sensor capabilities for variable rate irrigation management

USDA-ARS?s Scientific Manuscript database

Irrigation scheduling using soil water sensors aims at maintaining the soil water content in the crop root zone above a lower limit defined by the management allowed depletion (MAD) for that soil and crop, but not so wet that too much water is lost to deep percolation, evaporation and runoff or that...

Aquarium Microbiome Response to Ninety-Percent System Water Change: Clues to Microbiome Management

PubMed Central

Van Bonn, William; LaPointe, Allen; Gibbons, Sean M.; Frazier, Angel; Hampton-Marcell, Jarrad; Gilbert, Jack

2016-01-01

The bacterial community composition and structure of water from an established teleost fish system was examined before, during and after a major water change to explore the impact of such a water-change disturbance on the stability of the aquarium water microbiome. The diversity and evenness of the bacterial community significantly increased following the 90% water replacement. While the change in bacterial community structure was significant, it was slight, and was also weakly correlated with changes in physicochemical parameters. Interestingly there was a significant shift in the correlative network relationships between operational taxonomic units from before to after the water replacement. We suggest this shift in network structure is due to the turnover of many taxa during the course of water replacement. These observations will inform future studies into manipulation of the microbiome by changing system environmental parameter values to optimize resident animal health. PMID:26031788

Aquarium microbiome response to ninety-percent system water change: Clues to microbiome management.

PubMed

Van Bonn, William; LaPointe, Allen; Gibbons, Sean M; Frazier, Angel; Hampton-Marcell, Jarrad; Gilbert, Jack

2015-01-01

The bacterial community composition and structure of water from an established teleost fish system was examined before, during and after a major water change to explore the impact of such a water-change disturbance on the stability of the aquarium water microbiome. The diversity and evenness of the bacterial community significantly increased following the 90% water replacement. While the change in bacterial community structure was significant, it was slight, and was also weakly correlated with changes in physicochemical parameters. Interestingly there was a significant shift in the correlative network relationships between operational taxonomic units from before to after the water replacement. We suggest this shift in network structure is due to the turnover of many taxa during the course of water replacement. These observations will inform future studies into manipulation of the microbiome by changing system environmental parameter values to optimize resident animal health. © 2015 Wiley Periodicals, Inc.

Public Sector Unionization: Understanding the Rise in Membership Rates and Impact on Homeland Security

DTIC Science & Technology

2011-12-01

Travelers were reluctant to fly, flights were cancelled or had minimal passengers onboard as the public lost trust in the safety of air travel . 10...could be pulled into service to replace the striking screeners, airlines could cancel flights, and Americans could lose trust in air travel security...passenger travel , economic benefits of air travel enable globalization of world markets. Products and goods transported by air represent 35% of all

Modern Writing: The Effect of Process on Product and Perception

DTIC Science & Technology

2009-04-01

news cycles and reality telcvision. Thcse have contributed to the dilemma of blogs versus books, or in some cases, blogs as books. Although these two...mirror today, and in the tradition of these tails , people expect us to maintain these Knightly virtues. ll Sir Gawain and the Green Knight may best...illusions of courage and noble sacrifice - had all been lost for them that first time and long since replaced by cynicism and a conviction of the

General Design Memorandum, Gulfport Harbor, Mississippi. Design Memorandum Number 1. Appendix D. Environmental Documentation

DTIC Science & Technology

1989-06-01

thousands of acres of wetlands have been lost as a result of rapid coastal development. In view of their important ecological functions, it becomes... ecological roles: 1. trap sediment and stabilize bottom sediments; 2. carry on basic productivity that, in the eastern gulf, may considerably exceed the...be different, depending on the ecological attributes of the replacement habitat. This would result in no net loss of total habitat value, but might

Internal Prosthetic Replacement of Skeletal Segments Lost in Combat Related Injuries.

DTIC Science & Technology

1981-08-01

1-cm segment from the proximal third to prevent distraction of the fragments. The fiber metal segment is then placed in the appropriate defect and the...articularis genu suprema. The medial collateral ligament is sectioned through this incision and the medial meniscus removed in toto. The articular capsule...the image intensifier showed no evidence of motion. A physical therapy was instituted to mobilize and strengthen her knee. Case #11. This 52 year old

Hydrologic data for the Big Spring basin, Clayton County, Iowa, water year 1988

USGS Publications Warehouse

Kalkhoff, Stephen J.

1989-01-01

During a baseflow seepage study, June 28 and 29, the discharge lost by streams in the basin was 5.57 cubic feet per second and the dissolved nitrogen load lost was 0.19 tons per day. The discharge and total dissolved nitrogen leaving the basin in streams was 2.93 cubic feet per second and 0.02 tons per day, respectively.

Effects of developer exhaustion on Kodak EKTASPEED Plus, Ektaspeed, and Ultra-speed dental films.

PubMed

Thunthy, K H; Weinberg, R

1995-01-01

In 1994, Eastman Kodak Co. (Rochester, N.Y.) replaced its Ektaspeed film with the EKTASPEED Plus film. The manufacturer claims that one of the advantages of the new film is that it is not strongly affected by exhausted (depleted plus aged) processing solutions. The objective of the experiment was to test this claim. In exhausted solutions, EKTASPEED Plus film lost its speed more rapidly than Ultra-speed film but less rapidly than Ektaspeed film; that is, Ultra-speed film had the most stable speed. EKTASPEED Plus film lost contrast for 2 weeks before stabilizing, whereas Ultra-speed and Ektaspeed films continued to lose contrast for 3 weeks. Overall, EKTASPEED Plus film held its contrast over the other two films. EKTASPEED Plus film stopped increasing its film latitude after 2 weeks, whereas Ultra-speed and Ektaspeed films continued to increase film latitudes. In conclusion, for the three films studied, EKTASPEED Plus maintained the most constant levels of contrast and latitude in progressively exhausted solutions. All three films lost speed in exhausted solutions; EKTASPEED Plus film was the fastest but Ultra-speed film had the most stable speed.

Loss tolerant speech decoder for telecommunications

NASA Technical Reports Server (NTRS)

Prieto, Jr., Jaime L. (Inventor)

1999-01-01

A method and device for extrapolating past signal-history data for insertion into missing data segments in order to conceal digital speech frame errors. The extrapolation method uses past-signal history that is stored in a buffer. The method is implemented with a device that utilizes a finite-impulse response (FIR) multi-layer feed-forward artificial neural network that is trained by back-propagation for one-step extrapolation of speech compression algorithm (SCA) parameters. Once a speech connection has been established, the speech compression algorithm device begins sending encoded speech frames. As the speech frames are received, they are decoded and converted back into speech signal voltages. During the normal decoding process, pre-processing of the required SCA parameters will occur and the results stored in the past-history buffer. If a speech frame is detected to be lost or in error, then extrapolation modules are executed and replacement SCA parameters are generated and sent as the parameters required by the SCA. In this way, the information transfer to the SCA is transparent, and the SCA processing continues as usual. The listener will not normally notice that a speech frame has been lost because of the smooth transition between the last-received, lost, and next-received speech frames.

Isolation of sphere-forming stem cells from the mouse inner ear.

PubMed

Oshima, Kazuo; Senn, Pascal; Heller, Stefan

2009-01-01

The mammalian inner ear has very limited ability to regenerate lost sensory hair cells. This deficiency becomes apparent when hair cell loss leads to hearing loss as a result of either ototoxic insult or the aging process. Coincidently, with this inability to regenerate lost hair cells, the adult cochlea does not appear to harbor cells with a proliferative capacity that could serve as progenitor cells for lost cells. In contrast, adult mammalian vestibular sensory epithelia display a limited ability for hair cell regeneration, and sphere-forming cells with stem cell features can be isolated from the adult murine vestibular system. The neonatal inner ear, however, does harbor sphere-forming stem cells residing in cochlear and vestibular tissues. Here, we provide protocols to isolate sphere-forming stem cells from neonatal vestibular and cochlear sensory epithelia as well as from the spiral ganglion. We further describe procedures for sphere propagation, cell differentiation, and characterization of inner ear cell types derived from spheres. Sphere-forming stem cells from the mouse inner ear are an important tool for the development of cellular replacement strategies of damaged inner ears and are a bona fide progenitor cell source for transplantation studies.

Umbilical cord: an unlimited source of cells differentiable towards dopaminergic neurons

PubMed Central

Boroujeni, Mahdi Eskandarian; Gardaneh, Mossa

2017-01-01

Cell replacement therapy utilizing mesenchymal stem cells as its main resource holds great promise for ultimate treatment of human neurological disorders. Parkinson's disease (PD) is a common, chronic neurodegenerative disorder hallmarked by localized degeneration of a specific set of dopaminergic neurons within a midbrain sub-region. The specific cell type and confined location of degenerating neurons make cell replacement therapy ideal for PD treatment since it mainly requires replenishment of lost dopaminergic neurons with fresh and functional ones. Endogenous as well as exogenous cell sources have been identified as candidate targets for cell replacement therapy in PD. In this review, umbilical cord mesenchymal stem cells (UCMSCs) are discussed as they provide an inexpensive unlimited reservoir differentiable towards functional dopaminergic neurons that potentially lead to long-lasting behavioral recovery in PD patients. We also present miRNAs-mediated neuronal differentiation of UCMSCs. The UCMSCs bear a number of outstanding characteristics including their non-tumorigenic, low-immunogenic properties that make them ideal for cell replacement therapy purposes. Nevertheless, more investigations as well as controlled clinical trials are required to thoroughly confirm the efficacy of UCMSCs for therapeutic medical-grade applications in PD. PMID:28852404

The location and timing of magma degassing during Plinian eruptions

NASA Astrophysics Data System (ADS)

Giachetti, T.; Gonnermann, H. M.

2014-12-01

Water is the most abundant volatile species in explosively erupting silicic magmas and significantly affects magma viscosity, magma fragmentation and the dynamics of the eruption column. The effect that water has on these eruption processes can be modulated by outgassing degassing from a permeable magma. The magnitude, rate and timing of outgassing during magma ascent, in particular in relation to fragmentation, remains a subject of debate. Here we constrain how much, how fast and where the erupting magma lost its water during the 1060 CE Plinian phase of the Glass Mountain eruption of Medicine Lake Volcano, California. Using thermogravimetric analysis coupled with numerical modeling, we show that the magma lost >90% of its initial water upon eruption. Textural analyses of natural pumices, together with numerical modeling of magma ascent and degassing, indicate that 65-90% of the water exsolved before fragmentation, but very little was able to outgas before fragmentation. The magma attained permeability only within about 1 to 10 seconds before fragmenting and during that time interval permeable gas flow resulted in only a modest amount of gas flux from the un-fragmented magma. Instead, most of the water is lost shortly after fragmentation, because gas can escape rapidly from lapilli-size pyroclasts. This results in an efficient rarefaction of the gas-pyroclast mixture above the fragmentation level, indicating that the development of magma permeability and ensuing permeable outgassing are a necessary condition for sustain explosive eruptions of silicic magma. Magma permeability is thus a double-edged sword, it facilitates both, the effusive and the explosive eruption of silicic magma.

Maintenance costs of serotiny in a variably serotinous pine: The role of water supply.

PubMed

Martín-Sanz, Ruth C; Callejas-Díaz, Marta; Tonnabel, Jeanne; Climent, José M

2017-01-01

Serotiny is an important adaptation for plants in fire-prone environments. However, different mechanisms also induce the opening of serotinous cones in the absence of fire in variably serotinous species. Xeriscence -cone opening driven by dry and hot conditions- is considered to be mediated only by the external environment, but endogenous factors could also play a significant role. Using the variably serotinous Pinus halepensis as our model species, we determined the effects of cone age and scales density in cone opening, and using in-situ and ex-situ manipulative experiments we investigated the role of water availability in the opening of serotinous cones. We hypothesized that loss of connection between the cones and the branch through the peduncles or the absence of water supply could induce a faster cone opening. Results showed that older cones lost more water and opened at lower temperatures, with no influence of scales density. Both field and chamber manipulative experiments (using paired cones of the same whorl) confirmed that water intake through the peduncles affected significantly the pace of cone opening, such that lack of water supply speeded up cone dehiscence. However, this was true for weakly serotinous provenances-more common in this species-, while highly serotinous provenances were indifferent to this effect in the field test. All our results support that cone serotiny in P. halepensis involves the allocation of water to the cones, which is highly consistent with the previously observed environmental effects. Importantly, the existence of maintenance costs of serotinous cones has strong implications on the effects of climate change in the resilience of natural populations, via modifications of the canopy seed banks and recruitment after stand-replacing fires. Moreover, evolutionary models for serotiny in P. halepensis must take into account the significant contribution of maintenance costs to the complex interaction between genotype and the environment.

[How much water is lost during breathing?].

PubMed

Zieliński, Jakub; Przybylski, Jacek

2012-01-01

Arising from the Antoine equation and the ideal gas law, the volume of exhaled water has been calculated. Air temperature, humidity and minute ventilation has been taken into account. During physical exercise amount of exhaled H(2)O is linear, but not proportional to heart rate. And so at the heart rate of 140 bpm amount of exhaled water is approximately four times higher than during the rest and equals about 60-70 ml/h. The effect of external temperature and humidity on water lost via lungs was assessed as well. When temperature of inspired air and its humidity is 35°C an 75% respectively loss of water is 7 ml/h. Whereas when above parameters are changed to minus 10°C and 25% lung excretion of H(2)O increases up to 20 ml/h. The obtained results may become the basis for the assessment of osmolarity changes on the surface of the lower airways. The increase of which is recently considered as one of the factors responsible for exercise induced bronchospasm.

A simplified method for correcting contaminant concentrations in eggs for moisture loss.

USGS Publications Warehouse

Heinz, Gary H.; Stebbins, Katherine R.; Klimstra, Jon D.; Hoffman, David J.

2009-01-01

We developed a simplified and highly accurate method for correcting contaminant concentrations in eggs for the moisture that is lost from an egg during incubation. To make the correction, one injects water into the air cell of the egg until overflowing. The amount of water injected corrects almost perfectly for the amount of water lost during incubation or when an egg is left in the nest and dehydrates and deteriorates over time. To validate the new method we weighed freshly laid chicken (Gallus gallus) eggs and then incubated sets of fertile and dead eggs for either 12 or 19 d. We then injected water into the air cells of these eggs and verified that the weights after water injection were almost identical to the weights of the eggs when they were fresh. The advantages of the new method are its speed, accuracy, and simplicity: It does not require the calculation of a correction factor that has to be applied to each contaminant residue.

A Closed Loop System Using a Brine Reservoir to Replace Fresh Water as the Frac Fluid Source

EPA Pesticide Factsheets

A non-fresh water source, the Debolt formation, has been proposed and tested in the laboratory and field for application as a fracturing fluid in shale gas formations, with potential to replace much of the fresh water used in the Horn River Basin.

The effect of cool water pack preparation on vaccine vial temperatures in refrigerators.

PubMed

Goldwood, Geneva; Diesburg, Steven

2018-01-02

Cool water packs are a useful alternative to ice packs for preventing unintentional freezing of vaccines during outreach in some situations. Current guidelines recommend the use of a separate refrigerator for cooling water packs from ambient temperatures to prevent possible heat degradation of adjacent vaccine vials. To investigate whether this additional equipment is necessary, we measured the temperatures that vaccine vials were exposed to when warm water packs were placed next to vials in a refrigerator. We then calculated the effect of repeated vial exposure to those temperatures on vaccine vial monitor status to estimate the impact to the vaccine. Vials were tested in a variety of configurations, varying the number and locations of vials and water packs in the refrigerator. The calculated average percentage life lost during a month of repeated warming ranged from 20.0% to 30.3% for a category 2 (least stable) vaccine vial monitor and from 3.8% to 6.0% for a category 7 (moderate stability) vaccine vial monitor, compared to 17.0% for category 2 vaccine vial monitors and 3.1% for category 7 vaccine vial monitors at a constant 5 °C. The number of vials, number of water packs, and locations of each impacted vial warming and therefore percentage life lost, but the vaccine vial monitor category had a higher impact on the average percentage life lost than any of the other parameters. The results suggest that damage to vaccines from repeated warming over the course of a month is not certain and that cooling water packs in a refrigerator where vaccines are being stored may be a useful practice if safe procedures are established. Copyright © 2017 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Advances in Decoding Axolotl Limb Regeneration.

PubMed

Haas, Brian J; Whited, Jessica L

2017-08-01

Humans and other mammals are limited in their natural abilities to regenerate lost body parts. By contrast, many salamanders are highly regenerative and can spontaneously replace lost limbs even as adults. Because salamander limbs are anatomically similar to human limbs, knowing how they regenerate should provide important clues for regenerative medicine. Although interest in understanding the mechanics of this process has never wavered, until recently researchers have been vexed by seemingly impenetrable logistics of working with these creatures at a molecular level. Chief among the problems has been the very large size of salamander genomes, and not a single salamander genome has been fully sequenced to date. Recently the enormous gap in sequence information has been bridged by approaches that leverage mRNA as the starting point. Together with functional experimentation, these data are rapidly enabling researchers to finally uncover the molecular mechanisms underpinning the astonishing biological process of limb regeneration. Copyright © 2017 Elsevier Ltd. All rights reserved.

Perioperative fluid therapy: defining a clinical algorithm between insufficient and excessive.

PubMed

Strunden, Mike S; Tank, Sascha; Kerner, Thoralf

2016-12-01

In the perioperative scenario, adequate fluid and volume therapy is a challenging task. Despite improved knowledge on the physiology of the vascular barrier function and its respective pathophysiologic disturbances during the perioperative process, clear-cut therapeutic principles are difficult to implement. Neglecting the physiologic basis of the vascular barrier and the cardiovascular system, numerous studies proclaiming different approaches to fluid and volume therapy do not provide a rationale, as various surgical and patient risk groups, and different fluid regimens combined with varying hemodynamic measures and variable algorithms led to conflicting results. This review refers to the physiologic basis and answers questions inseparably conjoined to a rational approach to perioperative fluid and volume therapy: Why does fluid get lost from the vasculature perioperatively? Whereto does it get lost? Based on current findings and rationale considerations, which fluid replacement algorithm could be implemented into clinical routine? Copyright © 2016 Elsevier Inc. All rights reserved.

Ineffectiveness of commercial weight-loss programs for achieving modest but meaningful weight loss: Systematic review and meta-analysis.

PubMed

McEvedy, Samantha M; Sullivan-Mort, Gillian; McLean, Siân A; Pascoe, Michaela C; Paxton, Susan J

2017-10-01

This study collates existing evidence regarding weight loss among overweight but otherwise healthy adults who use commercial weight-loss programs. Systematic search of 3 databases identified 11 randomized controlled trials and 14 observational studies of commercial meal-replacement, calorie-counting, or pre-packaged meal programs which met inclusion criteria. In meta-analysis using intention-to-treat data, 57 percent of individuals who commenced a commercial weight program lost less than 5 percent of their initial body weight. One in two (49%) studies reported attrition ≥30 percent. A second meta-analysis found that 37 percent of program completers lost less than 5 percent of initial body weight. We conclude that commercial weight-loss programs frequently fail to produce modest but clinically meaningful weight loss with high rates of attrition suggesting that many consumers find dietary changes required by these programs unsustainable.

Comparison of survival analysis and palliative care involvement in patients aged over 70 years choosing conservative management or renal replacement therapy in advanced chronic kidney disease.

PubMed

Hussain, Jamilla A; Mooney, Andrew; Russon, Lynne

2013-10-01

There are limited data on the outcomes of elderly patients with chronic kidney disease undergoing renal replacement therapy or conservative management. We aimed to compare survival, hospital admissions and palliative care access of patients aged over 70 years with chronic kidney disease stage 5 according to whether they chose renal replacement therapy or conservative management. Retrospective observational study. Patients aged over 70 years attending pre-dialysis clinic. In total, 172 patients chose conservative management and 269 chose renal replacement therapy. The renal replacement therapy group survived for longer when survival was taken from the time estimated glomerular filtration rate <20 mL/min (p < 0.0001), <15 mL/min (p < 0.0001) and <12 mL/min (p = 0.002). When factors influencing survival were stratified for both groups independently, renal replacement therapy failed to show a survival advantage over conservative management, in patients older than 80 years or with a World Health Organization performance score of 3 or more. There was also a significant reduction in the effect of renal replacement therapy on survival in patients with high Charlson's Comorbidity Index scores. The relative risk of an acute hospital admission (renal replacement therapy vs conservative management) was 1.6 (p < 0.05; 95% confidence interval = 1.14-2.13). A total of 47% of conservative management patients died in hospital, compared to 69% undergoing renal replacement therapy (Renal Registry data). Seventy-six percent of the conservative management group accessed community palliative care services compared to 0% of renal replacement therapy patients. For patients aged over 80 years, with a poor performance status or high co-morbidity scores, the survival advantage of renal replacement therapy over conservative management was lost at all levels of disease severity. Those accessing a conservative management pathway had greater access to palliative care services and were less likely to be admitted to or die in hospital.

Temporal Chemical Data for Sediment, Water, and Biological Samples from the Lava Cap Mine Superfund Site, Nevada County, California-2006-2008

USGS Publications Warehouse

Foster, Andrea L.; Ona-Nguema, Georges; Tufano, Kate; White, Richard III

2010-01-01

The Lava Cap Mine is located about 6 km east of the city of Grass Valley, Nevada County, California, at an elevation of about 900 m. Gold was hosted in quartz-carbonate veins typical of the Sierran Gold Belt, but the gold grain size was smaller and the abundance of sulfide minerals higher than in typical deposits. The vein system was discovered in 1860, but production was sporadic until the 1930s when two smaller operations on the site were consolidated, a flotation mill was built, and a 100-foot deep adit was driven to facilitate drainage and removal of water from the mine workings, which extended to 366 m. Peak production at the Lava Cap occurred between 1934 and 1943, when about 90,000 tons of ore per year were processed. To facilitate removal of the gold and accessory sulfide minerals, the ore was crushed to a very fine sand or silt grain size for processing. Mining operations at Lava Cap ceased in June 1943 due to War Production Board Order L-208 and did not resume after the end of World War II. Two tailings retention structures were built at the Lava Cap Mine. The first was a log dam located about 0.4 km below the flotation mill on Little Clipper Creek, and the second, built in 1938, was a larger earth fill and rip-rap structure constructed about 2 km downstream, which formed the water body now called Lost Lake. The log dam failed during a storm that began on December 31, 1996, and continued into January 1997; an estimated 8,000-10,000 m3 of tailings were released into Little Clipper Creek during this event. Most of the fine tailings were deposited in Lost Lake, dramatically increasing its turbidity and resulting in a temporary 1-1.5 m rise in lake level due to debris blocking the dam spillway. When the blockage was cleared, the lake level quickly lowered, leaving a ?bathtub ring? of very fine tailings deposited substantially above the water line. The U.S. Environmental Protection Agency (EPA) initiated emergency action in late 1997 at the mine site to reduce the possibility of future movement of tailings, and began an assessment of the risks posed by physical and chemical hazards at the site. The EPA's assessment identified arsenic (As) as the primary hazard of concern. Three main exposure routes were identified: inhalation/ingestion of mine tailings, dermal absorption/ingestion of As in lake water from swimming, and ingestion of As-contaminated ground water or surface water. Lost Lake is a private lake which is completely surrounded by low-density residential development. Prior to the dam failure, the lake was used by the local residents for swimming and boating. An estimated 1,776 people reside within one mile of the lake, and almost all residents of the area use potable groundwater for domestic use. Risk factors for human exposure to As derived from mine wastes were high enough to merit placement of the mine site and surrounding area on the National Priority List (commonly called ?Superfund?). The Lava Cap Mine Superfund site (LCMS) encompasses approximately 33 acres that include the mine site, the stretch of Little Clipper Creek between the mine and Lost Lake, the lake itself, and the area between the lake and the confluence of Little Clipper Creek with its parent stream, Clipper Creek. The area between the two creeks is named the ?deposition area? due to the estimated 24 m thick layer of tailings that were laid down there during and after active mining. The lobate structure of Lost Lake is also due to deposition in this area. The deposition area and Lost Lake are together estimated to contain 382,277 m3 of tailings. The primary goals of the EPA have been to minimize tailings movement downstream of Lost Lake and to ensure that residents in the area have drinking water that meets national water quality standards. EPA has officially decided to construct a public water supply line to deliver safe water to affected residences, since some residential wells in the area have As concentrations above the curr

Hazards of deep-sea fishing1

PubMed Central

Schilling, R. S. F.

1971-01-01

Schilling, R. S. F. (1971). Brit. J. industr. Med., 28, 27-35. Hazards of deep-sea fishing. During the nineteenth century sailing smacks suffered heavy losses at sea. Their replacement by steam trawlers and motor vessels reduced casualties to both ships and men. The accident mortality of fishermen in England and Wales has been grossly underestimated by the Registrar General of Births and Deaths because all but a few deaths at sea are reported separately to the Registrar General of Shipping and Seamen and are not taken into account in calculating mortality rates. By including deaths at sea in the period 1959-63, fishermen's standardized mortality ratio for accidents is increased from 466 to 1 726. Between 1958 and 1967, 92 fishermen on British trawlers lost their lives as a result of casualties to vessels; and 116 from individual accidents, mostly by drowning. The importance of individual accidents is emphasized by the fact that in years when ther was no heavy loss of life from vessel casualties, fishermen's fatal accident rates were at least twice those of coal miners and more than 20 times the rate of men in manufacturing industries. Crews of distant-water vessels have higher fatal accident rates than crews of near- and middle-water vessels (2·3 against 1·8 per 1 000 man-years); for skippers and mates on distant-water vessels the rate is 3·2 per 1 000 man-years which is higher than the corresponding rate of 2·6 for deck-hands and almost double that for other crew members. In 47 out of 90 trawlers lost or serioulsy damaged, the cause of the casualty was attributable to negligent navigation. Fatigue due to excessively long hours of work may contribute to casualties to both vessels and individuals. The Committee of Inquiry into Trawler Safety set up by the British Government after the loss of three trawlers in 1968 made many recommendations for higher standards of design, construction, and stability of vessels for the deep-sea fleet and for a reduction in the hours of work for deck-hands. The Committee also recommended the supply of a support ship at sea offering special services such as weather forecasting, medical and technical aid, and the provision of occupational health services for fishermen in port. PMID:5101166

Water Harvesting II: Working toward Being Green

ERIC Educational Resources Information Center

Farenga, Stephen J.; Ness, Daniel; Craven, John A.

2008-01-01

As you have read in the previous "After the Bell" column, water harvesting is a process of diverting and collecting rainwater. One of the main reasons to harvest rainwater is to reduce the demand on local sources of water. The objective of the harvesting procedure is to gather water from a weather event that is usually lost as runoff and either…

Drought and Winter Drying (Pest Alert)

Treesearch

USDA Forest Service

Drought and winter drying have periodically caused major damage to trees. Drought reduces the amount of water available in the soil. In the case of winter drying, the water may be in the soil, but freezing of the soil makes the water unavailable to the tree. In both cases, more water is lost through transpiration than is available to the plant. Symptoms of drought and...

Developmental Toxicity Evaluations of Whole Mixtures of Disinfection By-products using Concentrated Drinking Water in Rats: Gestational and Lactational Effects of Sulfate and Sodium

EPA Science Inventory

A developmental toxicity bioassay was used in three experiments to evaluate drinking water concentrates for suitability in multigenerational studies. First, chlorinated water was concentrated 135 fold by reverse osmosis; select lost disinfection by-products were spiked back. Co...

Developmental Toxicity Evaluations of Whole Mixtures of Disinfection By-products using Concentrated Drinking Water in Rats: Gestational and Lactational Effects of Sulfate and Sodium*

EPA Science Inventory

A developmental toxicity bioassay was used in three experiments to evaluate drinking water concentrates for suitability in multigenerational studies. First, chlorinated water was concentrated 135 fold by reverse osmosis; select lost disinfection by-products were spiked back. Conc...

Hydrologic Analysis of Fort Leonard Wood, Missouri

DTIC Science & Technology

2015-08-01

of water available to FLW from the Roubidoux Creek drainage . In this case, because water is lost to the groundwater system while flowing through...taken from the Roubidoux Creek drainage . Roubidoux Creek is intermittent, and the stream loses water to the groundwater system as it flows through...13 Figure 5. FLW drainage divide

Satellite-based mapping of field-scale stress indicators for crop yield forecasting: an application over Mead, NE

USDA-ARS?s Scientific Manuscript database

In global agricultural regions, water is one of the most widely limiting factors of crop performance and production. Evapotranspiration (ET) describes crop water use through transpiration and water lost through direct soil evaporation, which makes it a good indicator of soil moisture availability an...

Depth to water, 1991, in the Rathdrum Prairie, Idaho; Spokane River valley, Washington; Moscow-Lewiston-Grangeville area, Idaho; and selected intermontane valleys, east-central Idaho

USGS Publications Warehouse

Berenbrock, Charles E.; Bassick, M.D.; Rogers, T.L.; Garcia, S.P.

1995-01-01

This map report illustrates digitally generated depth-to-water zones for the Rathdrum Prairie in Idaho; part of the Spokane River Valley in eastern Washington; and the intermontane valleys of the upper Big Wood, Big Lost, Pahsimeroi, Little Lost, and Lemhi Rivers and Birch Creek in Idaho. Depth to water is 400 to 500 feet below land surface in the northern part of Rathdrum Prairie, 100 to 200 feet below land surface at the Idaho-Washington State line, and 0 to 250 feet below land surface in the Spokane area. Depth to water in the intermontane valleys in east-central Idaho is least (usually less than 50 feet) near streams and increases toward valley margins where mountain-front alluvial fans have formed. Depths to water shown in the Moscow-Lewiston-Grangeville area in Idaho are limited to point data at individual wells because most of the water levels measured were not representative of levels in the uppermost aquifer but of levels in deeper aquifers.

Structure, attachment, replacement and growth of teeth in bluefish, Pomatomus saltatrix (Linnaeus, 1776), a teleost with deeply socketed teeth.

PubMed

Bemis, William E; Giuliano, Anne; McGuire, Betty

2005-01-01

Tooth replacement poses many questions about development, pattern formation, tooth attachment mechanisms, functional morphology and the evolution of vertebrate dentitions. Although most vertebrate species have polyphyodont dentitions, detailed knowledge of tooth structure and replacement is poor for most groups, particularly actinopterygians. We examined the oral dentition of the bluefish, Pomatomus saltatrix, a pelagic and coastal marine predator, using a sample of 50 individuals. The oral teeth are located on the dentary and premaxillary bones, and we scored each tooth locus in the dentary and premaxillary bones using a four-part functional classification: absent (A), incoming (I), functional (F=fully ankylosed) or eroding (E). The homodont oral teeth of Pomatomus are sharp, deeply socketed and firmly ankylosed to the bone of attachment. Replacement is intraosseus and occurs in alternate tooth loci with long waves of replacement passing from rear to front. The much higher percentage of functional as opposed to eroding teeth suggests that replacement rates are low but that individual teeth are quickly lost once erosion begins. Tooth number increases ontogenetically, ranging from 15-31 dentary teeth and 15-39 premaxillary teeth in the sample studied. Teeth increase in size with every replacement cycle. Remodeling of the attachment bone occurs continuously to accommodate growth. New tooth germs originate from a discontinuous dental lamina and migrate from the lingual (dentary) or labial (premaxillary) epithelium through pores in the bone of attachment into the resorption spaces beneath the existing teeth. Pomatomus shares unique aspects of tooth replacement with barracudas and other scombroids and this supports the interpretation that Pomatomus is more closely related to scombroids than to carangoids.

Long-term impacts of land cover changes on stream channel loss.

PubMed

Julian, Jason P; Wilgruber, Nicholas A; de Beurs, Kirsten M; Mayer, Paul M; Jawarneh, Rana N

2015-12-15

Land cover change and stream channel loss are two related global environmental changes that are expanding and intensifying. Here, we examine how different types and transitions of land cover change impact stream channel loss across a large urbanizing watershed. We present historical land cover in the 666-km(2) Lake Thunderbird watershed in central Oklahoma (USA) over a 137 year period and coinciding stream channel length changes for the most recent 70 years of this period. Combining these two datasets allowed us to assess the interaction of land cover changes with stream channel loss. Over this period, the upper third of the watershed shifted from predominantly native grassland to an agricultural landscape, followed by widespread urbanization. The lower two-thirds of the watershed changed from a forested landscape to a mosaic of agriculture, urban, forest, and open water. Most channel length lost in the watershed over time was replaced by agriculture. Urban development gradually increased channel loss and disconnection from 1942 to 2011, particularly in the headwaters. Intensities of channel loss for both agriculture and urban increased over time. The two longest connected segments of channel loss came from the creation of two large impoundments, resulting in 46 km and 25 km of lost stream channel, respectively. Overall, the results from this study demonstrate that multiple and various land-use changes over long time periods can lead to rapid losses of large channel lengths as well as gradual (but increasing) losses of small channel lengths across all stream sizes. When these stream channel losses are taken into account, the environmental impacts of anthropogenic land-use change are compounded. Copyright © 2015 Elsevier B.V. All rights reserved.

Application of natural resource valuation concepts for development of sustainable remediation plans for groundwater.

PubMed

Connor, John A; Paquette, Shawn; McHugh, Thomas; Gie, Elaine; Hemingway, Mark; Bianchi, Gino

2017-12-15

This paper explores the application of natural resource assessment and valuation procedures as a tool for developing groundwater remediation strategies that achieve the objectives for health and environmental protection, in balance with considerations of economic viability and conservation of natural resources. The natural resource assessment process, as applied under U.S. and international guidelines, entails characterization of groundwater contamination in terms of the pre-existing beneficial services of the impacted resource, the loss of these services caused by the contamination, and the measures and associated costs necessary to restore or replace the lost services. Under many regulatory programs, groundwater remediation objectives assume that the impacted groundwater may be used as a primary source of drinking water in the future, even if not presently in use. In combination with a regulatory preference for removal or treatment technologies, this assumed exposure, while protective of human health, can drive the remedy selection process toward remedies that may not be protective of the groundwater resource itself or of the other natural resources (energy, materials, chemicals, etc.) that may be consumed in the remediation effort. To achieve the same health and environmental protection goals under a sustainable remediation framework, natural resource assessment methods can be applied to restore the lost services and preserve the intact services of the groundwater so as to protect both current and future users of that resource. In this paper, we provide practical guidelines for use of natural resource assessment procedures in the remedy selection process and present a case study demonstrating the use of these protocols for development of sustainable remediation strategies. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

Characterization Report to Support the Phytoremediation Efforts for Southern Sector, Savannah River Site, Aiken, South Carolina

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jerome, K.M.

1999-06-08

In February, 1999, we conducted a small-scale characterization effort to support future remediation decisions for the Southern Sector of the upper Three Runs watershed. The study concentrated on groundwater adjacent to the seepline at Tim's Branch above and below Steed's Pond. the primary compounds of interest were the volatile organic contaminants (VOCs), trichlorethylene (TCE) and tetrachloroethylene (PCE). Due to the site topography and hydrogeology, samples collected north of Steed's Pond were from the M-Area (water table) aquifer; while those locations south of Steed's Pond provided samples from the Lost Lake aquifer. Results of the study suggest that the leading edgemore » of the A/M Area plume in the Lost Lake aquifer may be approaching the seepline at Tim's Branch below Steed's Pond, south of Road 2. Neither TCE nor PCE were detected int he samples targeting the seepline of the water table aquifer. The concentrations found for both TCE and PCE associated with the Lost Lake aquifer outcrop region were slightly above the detection limit of the analytical instrument used. The findings of this study are consistent with the conceptual model for the organic contaminant plume in the A/M Area of the Savannah River Site (SRS) -- the plume in the Southern Sector is known to be depth discrete and primarily in the Lost lake Aquifer. The sites with detected VOCs are in the most upstream accessible reaches of Tim's Branch where water from the Lost Lake Aquifer crops out. Additional characterization efforts should be directed near this region to confirm the results and to support future planning for the dilute-distal portions of the A/M Area plume. These data, combined with existing groundwater plume data and future characterization results will provide key information to estimate potential contaminant flux to the seepline and to assess the effectiveness of potential clean-up activities such as phytoremediation.« less

Modeling the Effect of Replacing Sugar-Sweetened Beverage Consumption with Water on Energy Intake, HBI Score, and Obesity Prevalence.

PubMed

Duffey, Kiyah J; Poti, Jennifer

2016-06-28

Sugar-sweetened beverages (SSB) contribute to excessive weight gain through added energy intake. Replacing SSB with water is one strategy that has shown promise in helping lower excessive energy intake. Using nationally representative data from US adults (n = 19,718) from NHANES 2007-2012 we examine the impact of replacing SSB with water on Healthy Beverage Index (HBI) scores and obesity prevalence. Replacing an 8-ounce serving of SSB with water lowered the percent of energy from beverages from 17% to 11% (among those consuming 1 serving SSB/day). Reductions in the percent energy from beverages were observed across all SSB consumption groups (1-2 servings/day and >2 servings/day). Among adults there was a 9% to 21% improvement in HBI score when one serving of water replaced one serving of SSB. Using previously published randomized controlled trials (RCT) and meta-analyses of measured weight loss we also predicted a reduction in the prevalence of obesity (observed: 35.2%; predicted 33.5%-34.9%, p < 0.05) and increase in the prevalence of normal weight (observed: 29.7%; high weight loss: 31.3%, p < 0.05). Our findings provide further epidemiologic evidence that water in the place of SSB can be used as a strategy to limit energy intake and help individuals meet beverage intake recommendations.

Modeling the Effect of Replacing Sugar-Sweetened Beverage Consumption with Water on Energy Intake, HBI Score, and Obesity Prevalence

PubMed Central

Duffey, Kiyah J.; Poti, Jennifer

2016-01-01

Sugar-sweetened beverages (SSB) contribute to excessive weight gain through added energy intake. Replacing SSB with water is one strategy that has shown promise in helping lower excessive energy intake. Using nationally representative data from US adults (n = 19,718) from NHANES 2007–2012 we examine the impact of replacing SSB with water on Healthy Beverage Index (HBI) scores and obesity prevalence. Replacing an 8-ounce serving of SSB with water lowered the percent of energy from beverages from 17% to 11% (among those consuming 1 serving SSB/day). Reductions in the percent energy from beverages were observed across all SSB consumption groups (1–2 servings/day and >2 servings/day). Among adults there was a 9% to 21% improvement in HBI score when one serving of water replaced one serving of SSB. Using previously published randomized controlled trials (RCT) and meta-analyses of measured weight loss we also predicted a reduction in the prevalence of obesity (observed: 35.2%; predicted 33.5%–34.9%, p < 0.05) and increase in the prevalence of normal weight (observed: 29.7%; high weight loss: 31.3%, p < 0.05). Our findings provide further epidemiologic evidence that water in the place of SSB can be used as a strategy to limit energy intake and help individuals meet beverage intake recommendations. PMID:27367719

Assessing of the potential of extruded flour paste as fat replacer in O/W emulsion: A rheological and microstructural study.

PubMed

Román, Laura; Martínez, Mario M; Gómez, Manuel

2015-08-01

Extruded flour represents an economical and environmental friendly alternative as fat replacer. In this research, the potential use of an extruded flour-water paste as fat replacer in an oil-in-water emulsion was studied. The effect of flour-water ratio and level of oil replacement (30, 50 and 70%) on the microstructure, rheological properties and stability of mayonnaise-like emulsion was evaluated. Fat replacement by extruded flour gradually increased the number and reduced the size of oil droplets. All the emulsion samples showed a pseudoplastic behaviour. At low shear rates a Newtonian region characterised by Carreau model appeared (R 2 >0.99). In general, the limiting viscosity of the Newtonian region and the consistency index increased with the decreased water content of the paste and increased the level of oil substitution. A decrease in oil concentration led to a greater thixotropic behaviour. Oscillatory test revealed that predominance of the continuous or dispersed phase influenced viscoelastic behaviour. Reduction in oil content resulted in an increased freeze-thaw stability. Results suggested that if the flour-water ratio of the paste is controlled, extruded flour is appropriate for preparing reduced-fat oil-in-water emulsion with similar rheological properties to the full fat and greater freeze-thaw stability. Copyright © 2015 Elsevier Ltd. All rights reserved.

Influence of white plastic and water replacement rates on pomegranate orchard phenology, fruit yield and quality

USDA-ARS?s Scientific Manuscript database

Currently, 98% of domestic commercial pomegranate fruit (Punica granatum L.) are produced in California on over 13,000 ha. In 2013, a pomegranate orchard, established in 2010 with a density of 558 trees/ha, was irrigated at water replacement rates of 35, 50 and 100% based on rainfall, tree water r...

Space Based Radar-System Architecture Design and Optimization for a Space Based Replacement to AWACS

DTIC Science & Technology

1997-09-08

Davis Highway, Suite 1204, Arlington, VA 22202-4302, aod to the Office of Maoagement aod Bidget , Paperwork Reductioo Project 10704-0188), Washiogtoo...waveforms delayed by a time increment equal to the wave travel time. Note that the cross-correlation between the signal and noise is approximately zero. This...the discrete increments of satellites that can be lost The paradigm of reliability for losing a certain number of satellites is an inn-1 0.95

Gopherus agassizii (Agassiz’s desert tortoise). scute dysecdysis/scute sloughing

USGS Publications Warehouse

Nussear, Kenneth E.; Drake, Karla K.; Medica, Phil A.; Esque, Todd C.

2012-01-01

Desert tortoises with scute injuries due to fire or disease related processes can result in loss of the scute. These animals appear to function normally, and can replace the scute material with a keratinized layer that covers the bone. This paper describes a tortoise with severe scute loss from a wildfire in 2005, and an animal that lost its scute for unknown reasons. Both animals appeared to be healthy in all other aspects, and lived for many years afterward.

ASC Addresses Unit Commanders’ Concerns through LBE and Reset Programs

DTIC Science & Technology

2008-09-01

Distribution Management Center (DMC). The DMC, based at ASC Headquarters on Rock Island Arsenal, Ilinois, has become the single ASC integrator for LBE and field-level reset in support of ARFORGEN. The reset of units returning from OEF/OIF consists of a series of actions to restore the units to a desired level of combat capability commensurate with future mission requirements. These actions include the repair of equipment, replacement of equipment lost during operations, and recapitalization of equipment where feasible and

Measurement of H2O and other trace gases in the stratosphere using a high resolution far-infrared spectrometer at 28 KM

NASA Technical Reports Server (NTRS)

Traub, W. A.; Chance, K. V.

1986-01-01

The highlights of the stratospheric program were reviewed for the past 2.5 years. The major efforts were analysis of the data from the BIC-2 campaign, and the building or new instrumentation to replace that lost at the end of BIC-2. For clarity, the review will be done by topic, rather than chronologically: construction of the initial far-infrared spectrometer, balloon slight program, laboratory measurement, data analysis, and duplicate stabilized platform.

WATER DISTRIBUTION SYSTEMS: A SPATIAL AND COST EVALUATION

EPA Science Inventory

Problems associated with maintaining and replacing water supply distribution systems are reviewed. Some of these problems are associated with public health, economic and spatial development of the community, and costs of repair and replacement of system components. A repair frequ...

Ad libitum vs. restricted fluid replacement on hydration and performance of military tasks.

PubMed

Nolte, Heinrich W; Noakes, Timothy D; Nolte, Kim

2013-02-01

The primary objective was to evaluate the effect of ad libitum vs. restricted fluid replacement protocol on hydration markers and performance in selected military tasks. The secondary objective was to determine if 300 ml x h(-1) could be considered a safe minimum fluid intake under the experimental conditions. Data were collected simulating a route march over 16 km. There were 57 subjects who participated in the study. The mean pre-exercise body mass of the ad libitum group was 70.4 +/- 13.3 (SD) kg compared to 69.3 +/- 8.9 kg in the restricted group. The mean total fluid intake of the ad libitum group was 2.1 +/- 0.9 L compared to 1.2 +/- 0.0 L in the restricted group. The ad libitum and restricted intake groups, respectively, lost a mean of 1.05 kg +/- 0.77 (1.5%) and 1.34 kg +/- 0.37 (1.9%). Calculated sweat rate was 608 +/- 93 ml x h(-1) compared to 762 +/- 162 ml x h(-1) in the ad libitum group. There were no significant differences for either urine specific gravity (USG) or urine osmolality (UOsm) before or after the exercise. It is not clear whether fluid intake and calculated sweat rates are causally related or explained by their codependence on a third variable; for example, the exercising metabolic rate. Thus, 300 ml x h(-1) intake could be considered a current safe minimum water intake for soldiers of similar mass under similar experimental conditions, namely similar exercise durations at equivalent exercise intensities in a moderate, dry climate.

Naturally Occurring Arsenic in Ground Water, Norman, Oklahoma, 2004, and Remediation Options for Produced Water

USGS Publications Warehouse

Smith, S. Jerrod; Christenson, Scott

2005-01-01

In 2000, the U.S. Environmental Protection Agency (EPA) reviewed the arsenic drinking water standard for public water supplies. Considering the available research and statistics on the health effects of arsenic ingestion, the EPA reduced the Maximum Contaminant Level (MCL) for public drinking water from 50 micrograms per liter (?g/L) to 10 ?g/L (U.S. Environmental Protection Agency, 2001a). As a result of the more stringent standard, the EPA estimates that about 3,000 public water providers across the United States must take action to meet the new standard before it becomes effective on January 23, 2006 (U.S. Environmental Protection Agency, 2001b). The City of Norman (City) is one of several Oklahoma municipalities affected by the new arsenic standard. About 20 percent of Norman?s water is supplied by wells completed in the Central Oklahoma (Garber-Wellington) aquifer; the rest is supplied by Lake Thunderbird (fig. 1) or purchased from Oklahoma City. The Norman well field is composed of 24 active wells, and water produced from about half of the wells will not be in compliance with the new MCL (figs. 2 and 3). Chemical treatment of water with elevated arsenic is possible, but it is generally cost prohibitive. Another costly solution is simply to abandon the high-arsenic wells and replace them with new wells in low-arsenic areas. In the next phase of well construction beginning in 2005, the City plans to construct as many as 30 new wells in northeast Norman (Bryan Mitchell, City of Norman, oral commun., 2005). The new wells will replace production lost to the new arsenic standard and add new production to keep pace with rapidly growing consumer demand. Well modification to exclude arsenic-bearing water from existing wells is a more cost-effective solution, but it requires a great deal of knowledge about local aquifer properties and individual well dynamics to decide which wells are good candidates for modification. With the goal of determining if well modification can be used to bring some of Norman?s high-arsenic wells into compliance with the new arsenic standard, the EPA Office of Research and Development (ORD) initiated a three-year research project in 2003 with participation from the U.S. Geological Survey (USGS), Oklahoma State University, and the City of Norman. The primary objectives of the project are to: (1) determine where naturally occurring arsenic is entering wells by collecting water samples at different depths, (2) investigate the utility of new methods for collecting water-quality data in a pumping well, (3) better understand the stratigraphy and composition of aquifer rocks, (4) assess 10 wells for the possibility of arsenic remediation by well modification, and (5) evaluate the effectiveness of well modification in bringing marginal wells into compliance with the new arsenic MCL. The purpose of this report is to describe the occurrence of arsenic in ground water near Norman, Oklahoma, and available options for reducing arsenic concentrations in produced ground water.

The feasibility of replacing or upgrading utility distribution transformers during routine maintenance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barnes, P.R.; Van Dyke, J.W.; McConnell, B.W.

It is estimated that electric utilities use about 40 million distribution transformers in supplying electricity to customers in the United States. Although utility distribution transformers collectively have a high average efficiency, they account for approximately 61 billion kWh of the 229 billion kWh of energy lost annually in the delivery of electricity. Distribution transformers are being replaced over time by new, more efficient, lower-loss units during routine utility maintenance of power distribution systems. Maintenance is typically not performed on units in service. However, units removed from service with appreciable remaining life are often refurbished and returned to stock. Distribution transformersmore » may be removed from service for many reasons, including failure, over- or underloading, or line upgrades such as voltage changes or rerouting. When distribution transformers are removed from service, a decision must be made whether to dispose of the transformer and purchase a lower-loss replacement or to refurbish the transformer and return it to stock for future use. This report contains findings and recommendations on replacing utility distribution transformers during routine maintenance, which is required by section 124(c) of the Energy Policy Act of 1992. The objectives of the study are to evaluate the practicability, cost-effectiveness, and potential energy savings of replacing or upgrading existing transformers during routine utility maintenance and to develop recommendations on was to achieve the potential energy savings.« less

Effects of a meal replacement system alone or in combination with phentermine on weight loss and food cravings.

PubMed

Moldovan, Christina P; Weldon, Abby J; Daher, Noha S; Schneider, Louise E; Bellinger, Denise L; Berk, Lee S; Hermé, Alyson C; Aréchiga, Adam L; Davis, Willie L; Peters, Warren R

2016-11-01

To examine the effects of phentermine combined with a meal replacement program on weight loss and food cravings and to investigate the relationship between food cravings and weight loss. In a 12-week randomized, double-blind, placebo-controlled clinical trial, 77 adults with obesity received either phentermine or placebo. All participants were provided Medifast ® meal replacements, were instructed to follow the Take Shape for Life ® Optimal Weight 5&1 Plan for weight loss, and received lifestyle coaching in the Habits of Health program. The Food Craving Inventory and the General Food Cravings State and Trait Questionnaires were used to measure food cravings. The phentermine group lost 12.1% of baseline body weight compared with 8.8% in the placebo group. Cravings for all food groups decreased in both groups; however, there was a greater reduction in cravings for fats and sweets in the phentermine group compared with the placebo group. Percent weight loss correlated significantly with reduced total food cravings (r = 0.332, P = 0.009), cravings for sweets (r = 0.412, P < 0.000), and state food cravings (r = 0.320, P = 0.007). Both phentermine combined with a meal replacement program and meal replacements alone significantly reduced body weight and food cravings; however, the addition of phentermine enhanced these effects. © 2016 The Obesity Society.

Correcting the thermal inefficiencies of a cogeneration and boiler plant by low-pressure steam conversions and hot water thermal energy storage

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pals, C.M.

1998-12-31

A liberal arts college in Los Angeles was plagued by inefficient use of low-pressure (LP) steam produced by its two 150 kWe cogeneration units. Poor integration of the LP cogen system into the college`s existing high-pressure (HP) steam boiler plant led to under-utilization of cogenerated steam during the non-space-heating season. Six years of inefficient operation was estimated to have cost the college $750,000 in lost utility and maintenance savings. To improve steam-plant operations, the college`s facilities management staff implemented a plan to convert HP steam loads to LP, replace HP steam boilers with LP equipment, and improve the use ofmore » cogenerated steam through the installation of a hot water thermal energy storage (TES) system. A study was commissioned that identified the plant`s peak winter steam requirements and the typical steam profile for the non-space-heating season. Data from this work helped draw two conclusions: (1) converting HP steam loads to LP would boost demand for cogenerated steam, and (2) a hot water thermal energy storage (TES) system could further utilize a portion of remaining excess cogen steam for the manufacture and storage of the kitchen`s domestic water for use during peak steam demand periods. Combined, these two measures were estimated to improve utilization of cogenerated LP steam by 11,000 pounds (5,000 kg) per day and reduce boiler fuel consumption by 40,000 therms (4,220,000 MJ) each season. In addition to this work, a major plant renovation project was completed, which included the replacement of a 60-year-old, 280 bhp (2,747 kW) HP steam boiler, with two new LP boilers. Conversion to LP and the start-up of the hot water TES was completed in May 1997. During the first year of operation, after the improvement, boiler gas savings exceeded 52,000 therms (5,486,000 MJ). Maintenance savings of $100,000 were also accrued by eliminating licensed HP boiler operators. All construction work described to improve energy efficiency and rehabilitate the steam plant cost $687,000 and is on track to produce a simple payback of 5.5 years. Overall, this paper demonstrates the energy and cost inefficiencies that may result if the opportunities to use waste heat from cogeneration systems are incorrectly identified.« less

DETERMINANTS AND OPTIONS FOR WATER DISTRIBUTION SYSTEM MANAGEMENT: A COST EVALUATION

EPA Science Inventory

This report deals with the problems associated with maintaining and replacing water supply distribution systems. Some of these problems are associated with public health, economic and spatial development of the community, and costs of repair and replacement of system components. ...

Simulation of streamflow and the effects of brush management on water yields in the Double Mountain Fork Brazos River watershed, western Texas 1994–2013

USGS Publications Warehouse

Harwell, Glenn R.; Stengel, Victoria G.; Bumgarner, Johnathan R.

2016-04-20

The calibrated watershed model was used to perform brush-management simulations. The National Land Cover Database 2006, which was the land-cover data used to develop the watershed model, was modified to simulate shrubland replacement with grassland in each of the 35 model subbasins. After replacement of shrubland with grassland in areas with land slope less than 20 percent and excluding riparian areas, the modeled 20-year (1994 through 2013) water yields to Lake Alan Henry increased by 114,000 acre-feet or about 5,700 acre-feet per year. In terms of the increase in water yield per acre of shrubland replaced with grassland, the average annual increase in water yield was 17,300 gallons per acre. Within the modeled subbasins, the increase in average annual water yield ranged from 5,850 to 34,400 gallons per acre of shrubland replaced with grassland. Subbasins downstream from the Justiceburg gage had a higher average annual increase in water yield (21,700 gallons per acre) than subbasins upstream from the streamflow-gaging station (16,800 gallons per acre).

Subsurface information from eight wells drilled at the Idaho National Engineering Laboratory, southeastern Idaho

USGS Publications Warehouse

Goldstein, F.J.; Weight, W.D.

1982-01-01

The Idaho National Engineering Laboratory (INEL) covers about 890 square miles of the eastern Snake River Plain, in southeastern Idaho. The eastern Snake River Plain is a structural basin which has been filled with thin basaltic lava flows, rhyolitic deposits, and interbedded sediments. These rocks form an extensive ground-water reservoir known as the Snake River Plain aquifer. Six wells were drilled and two existing wells were deepened at the INEL from 1969 through 1974. Interpretation of data from the drilling program confirms that the subsurface is dominated by basalt flows interbedded with layers of sediment, cinders, and silicic volcanic rocks. Water levels in the wells show cyclic seasonal fluctuations of maximum water levels in winter and minimum water levels in mid-summer. Water levels in three wells near the Big Lost River respond to changes in recharge to the Snake River Plain aquifer from the Big Lost River. Measured water levels in multiple piezometers in one well indicate increasing pressure heads with depth. A marked decline in water levels in the wells since 1977 is attributed to a lack of recharge to the Snake River Plain aquifer.

Soil Water: Advanced Crop and Soil Science. A Course of Study.

ERIC Educational Resources Information Center

Miller, Larry E.

The course of study represents the fourth of six modules in advanced crop and soil science and introduces the agriculture student to the topic of soil water. Upon completing the three day module, the student will be able to classify water as to its presence in the soil, outline the hydrological cycle, list the ways water is lost from the soil,…

Understanding the role of soil erosion on co2-c loss using (13)c isotopic signatures in abandoned Mediterranean agricultural land.

PubMed

Novara, Agata; Keesstra, Saskia; Cerdà, Artemio; Pereira, Paulo; Gristina, Luciano

2016-04-15

Understanding soil water erosion processes is essential to evaluate the redistribution of soil organic carbon (SOC) within a landscape and is fundamental to assess the role of soil erosion in the global carbon (C) budget. The main aim of this study was to estimate the C redistribution and losses using (13)C natural abundance. Carbon losses in soil sediment, dissolved organic carbon (DOC) and CO2 emission were determined. Four bounded parallel plots were installed on a 10% slope. In the upper part of the plots, C3soil was replaced with C4soil. The SOC and δ(13)C were measured after 145.2mm rainfall in the upper (2m far from C4strip), middle (4m far from C4strip) lower (6m far from C4strip) trams of the plot and in the sediments collected in the Gerlach collector at the lower part of the plot. A laboratory incubation experiment was performed to evaluate the CO2 emission rate of soils in each area. OC was mainly lost in the sediments as 2.08g(-)(2) of C was lost after 145.2mm rainfall. DOC losses were only 5.61% of off-site OC loss. Three months after the beginning of the experiment, 15.90% of SOC in the upper tram of the plot had a C4 origin. The C4-SOC content decreased along the 6m length of the plot, and in the sediments collected by the Gerlach collector. CO2 emission rate was high in the upper plot tram due to the high SOC content. The discrimination of CO2 in C3 and C4 portion permitted to increase our level of understanding on the stability of SOC and its resilience to decomposition. The transport of sediments along the plot increased SOC mineralization by 43%. Our study underlined the impact of rainfall in C losses in soil and water in abandoned Mediterranean agriculture fields and the consequent implications on the C balance. Copyright © 2016 Elsevier B.V. All rights reserved.

A GIS Analysis of Seagrass Resources and Condition Within Padre Island National Seashore, Texas

USGS Publications Warehouse

Onuf, Christopher P.; Ingold, Jaimie J.

2007-01-01

A survey of the seagrass resources of Padre Island National Seashore was conducted in fall 2002 and 2003, with additional sampling through 2006, to resolve distribution questions. Location coordinates were recorded to thousandths of minutes of latitude and longitude and converted to decimal degrees (minus decimal degrees for longitude) for import into ArcView (Environmental Systems Research Institute, Inc.). The seagrass core frequency data were developed as a theme in ArcView and overlaid on digital orthophoto quarter quadrangles of the U.S. Geological Survey to show sample depth with respect to mean sea level and frequency of occurrence of seagrass for five samples collected from every station sampled. These data were used to draw boundaries of area submerged at mean sea level and seagrass meadow in relation to the boundary of Padre Island National Seashore. Frequency of seagrass occurrence, mean plant height, shoot density, plant height multiplied by shoot density, live biomass, and dead biomass on a 1' latitude by 0.25' longitude grid were collected, and their distribution was plotted in space and according to depth. A User Guide for displaying data in ArcView is included at the end of this report. Seagrasses covered almost two-thirds of the regularly flooded part of Laguna Madre within the borders of Padre Island National Seashore. Comparisons with earlier surveys showed that substantial areas of seagrass cover had been lost in deep water between 1988 and 1998 as a result of a persistent phytoplankton bloom, and little recovery has occurred since. Maximum depth of seagrass occurrence responded to changes in water clarity. In contrast, much of the cover at shallow to intermediate depths lost at the south end of the study area between 1988 and 1998 was replaced by 2003. The seven stations with greatest plant height were located in this area of recent recolonization. Continuity of cover as measured by frequency of occurrence was high except near the edge of seagrass meadow. Decrease in this measure may be an indicator of meadow fragmentation, signaling deterioration of seagrass meadow before loss. The other measures of condition were so variable that they were insensitive indicators of impending change.

Adaptation: Forests as water infrastructure in a changing climate

Treesearch

Todd Gartner; Heather McGray; James Mulligan; Jonas Epstein; Ayesha Dinshaw

2014-01-01

Natural ecosystems like forests and wetlands provide a suite of water-related services that are increasingly critical for communities as the impacts of climate change intensify. Yet, these natural ecosystems are increasingly lost or degraded. In the face of growing water-related challenges in an age of fiscal austerity, investing in the conservation, restoration, and...

Nitrogen transformations in a waterhyacinth-based water treatment system. [Eichornia crassipes (Mart. ) Solms

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moorhead, K.K.; Reddy, K.R.; Graetz, D.A.

Fate of added /sup 15/NH/sub 4/-N and /sup 15/NO/sub 3/-N in waterhyacinth (Eichhornia crassipes (Mart.) Solms)-based water treatment system was evaluated under controlled conditions. Labeled /sup 15/NH/sub 4/-N uptake by waterhyacinth exceeded /sup 15/NO/sub 3/-N uptake. Total /sup 15/N recovery by waterhyacinth ranged from 57 to 72% for added /sup 15/NO/sub 3/-N and 70 to 89% for added /sup 15/NH/sub 4/-N. Both sediment and detritus were potential sources of N for waterhyacinths. Waterhyacinths cultured in sewage effluent removed 55% of the added /sup 15/NH/sub 4/-N and 14% of the added /sup 15/NO/sub 3/-N, respectively. Three to 44% of the addedmore » /sup 15/NH/sub 4/-N was lost through nitrification in the water column and subsequent denitrification in the underlying sediments, whereas 24 to 86% of the added /sup 15/NO/sub 3/-N was lost through denitrification. In a system without plants, 13 to 89% of the added /sup 15/NH/sub 4/-N and 48 to 96% of the added /sup 15/NO/sub 3/-N were lost from the system through a combination of nitrification/denitrification and NH/sub 3/ volatilization.« less

Digestive parameters and water turnover of the leopard tortoise.

PubMed

McMaster, Megan K; Downs, Colleen T

2008-09-01

Leopard tortoises (Stigmochelys pardalis) experience wide fluctuations in environmental conditions and unpredictable availability of food and water within the Nama-Karoo biome. It was hypothesised that tortoises fed two diets differing in preformed water and fibre content would have differing food intake, gut transit rate, assimilation efficiency, faecal and urinary water loss, and urine concentrations. It was predicted that tortoises fed these contrasting diets would attempt to maintain energy and water balance by altering their digestive parameters. Leopard tortoises fed lucerne (Medicago sativa) had a low food intake coupled with long gut transit times, which resulted in the lowest amount of faecal energy and faecal water lost. Tortoises fed tomatoes (Solanum lycopersicum) had higher food intake and faster gut transit times, but more energy and water was lost in the faeces. However, daily energy assimilated and assimilation efficiency were comparable between tortoises fed the two diets. Urine osmolality was significantly different between tortoises on the two diets. Results indicate that leopard tortoises can adjust parameters such as transit rate, food intake, water loss and urine osmolality to maintain body mass, water and energy balance in response to a high fibre, low water content and a low fibre, high water content diet. This study suggests that this digestive flexibility allows leopard tortoises in the wild to take advantage of unpredictable food and water resources.

Water Processing Assembly Particulate Filter Remove and Replace (R&R)

NASA Image and Video Library

2013-07-12

ISS036-E-018008 (12 July 2013) --- European Space Agency astronaut Luca Parmitano, Expedition 36 flight engineer, removes and replaces the particulate filter for the Water Pump Assembly 2 (WPA2) in Tranquility (also called Node 3) on the International Space Station.

Water Processing Assembly Particulate Filter Remove and Replace (R&R)

NASA Image and Video Library

2013-07-12

ISS036-E-018007 (12 July 2013) --- European Space Agency astronaut Luca Parmitano, Expedition 36 flight engineer, removes and replaces the particulate filter for the Water Pump Assembly 2 (WPA2) in Tranquility (also called Node 3) on the International Space Station.

Rehabilitation of Wastewater Collection and Water Distribution Systems

EPA Science Inventory

The nation’s 54,000 drinking water systems and 16,000 wastewater systems are nearing the end of their useful life and need to be replaced/repaired to comply with federal regulations. Rehabilitation includes a broad spectrum of approaches, from repair to replacement that attempt ...

Supplemental water releases for fisheries restoration in a Brazilian floodplain River: A conceptual model

USGS Publications Warehouse

Godinho, Alexandre L.; Kynard, B.; Martinez, C.B.

2007-01-01

Highly productive floodplain rivers in Brazil and elsewhere provide livelihood and recreational fishing for millions of people around the world, but damming and controlled water discharge are a threat to these valuable ecosystems. Supplemental water releases (SWRs) at a dam are increasingly used for restoring fisheries productivity in many floodplain rivers. We proposed a conceptual model for a hypothetical water release to enhance fisheries using Tre??s Marias Reservoir (TMR) on the Sa??o Francisco River (SFR), Brazil. The information needed by the model follows: (i) Biologically, what is the best release date? (ii) How much water will be released? (iii) What is the pattern of impoundment and how much impounded water will be released? (iv) What is the lost revenue to the power plant associated with SWR? (v) What is the relationship between river discharge and the area of floodplain that is flooded? (vi) What is the relationship between SWR and fisheries value? Ichthyoplankton studies in the SFR showed a clear positive relationship between fish density and water level (WL). While the relationship between WL and floodplain area flooded and recruitment is not known, we concluded the best date for release is when there is a natural flood, which naturally triggers fish spawning and the SWR will add to the natural flood and cover a greater floodplain area. The released volume will range from 0.302km3 to 2.192 km3, depending on SWR duration. In most years from 1976 to 2003, TMR impounded enough water for SWR only in the second half of the fish-spawning season (January-March). Lost revenue at TMR depended on release volume and ranged from US$ 0.493 million to US$ 3.452 million for the actual power rate. However, SWR could increase commercial fisheries income an estimated US$ 4.468 million. We forecast that SWR can bring fisheries benefits that surpass the lost revenue.

Predicted molecular signaling guiding photoreceptor cell migration following transplantation into damaged retina

NASA Astrophysics Data System (ADS)

Unachukwu, Uchenna John; Warren, Alice; Li, Ze; Mishra, Shawn; Zhou, Jing; Sauane, Moira; Lim, Hyungsik; Vazquez, Maribel; Redenti, Stephen

2016-03-01

To replace photoreceptors lost to disease or trauma and restore vision, laboratories around the world are investigating photoreceptor replacement strategies using subretinal transplantation of photoreceptor precursor cells (PPCs) and retinal progenitor cells (RPCs). Significant obstacles to advancement of photoreceptor cell-replacement include low migration rates of transplanted cells into host retina and an absence of data describing chemotactic signaling guiding migration of transplanted cells in the damaged retinal microenvironment. To elucidate chemotactic signaling guiding transplanted cell migration, bioinformatics modeling of PPC transplantation into light-damaged retina was performed. The bioinformatics modeling analyzed whole-genome expression data and matched PPC chemotactic cell-surface receptors to cognate ligands expressed in the light-damaged retinal microenvironment. A library of significantly predicted chemotactic ligand-receptor pairs, as well as downstream signaling networks was generated. PPC and RPC migration in microfluidic ligand gradients were analyzed using a highly predicted ligand-receptor pair, SDF-1α - CXCR4, and both PPCs and RPCs exhibited significant chemotaxis. This work present a systems level model and begins to elucidate molecular mechanisms involved in PPC and RPC migration within the damaged retinal microenvironment.

40 CFR 141.84 - Lead service line replacement requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 23 2011-07-01 2011-07-01 false Lead service line replacement requirements. 141.84 Section 141.84 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Control of Lead and Copper § 141.84 Lead...

40 CFR 141.84 - Lead service line replacement requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Lead service line replacement requirements. 141.84 Section 141.84 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Control of Lead and Copper § 141.84 Lead...

Guidelines for replacement of deficient bridges with low-water stream crossings in the rural Midwest.

DOT National Transportation Integrated Search

2017-02-01

This report provides guidance to public officials and engineers considering the replacement of a deficient or obsolete bridge with a low-water stream crossing (LWSC). An LWSC is a structure that is occasionally overtopped by floodwaters and is likely...

18 CFR 367.57 - Equipment.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Equipment. 367.57 Section 367.57 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT... equipment accounts hand and other portable tools, that are likely to be lost or stolen or that have...

18 CFR 367.57 - Equipment.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Equipment. 367.57 Section 367.57 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT... equipment accounts hand and other portable tools, that are likely to be lost or stolen or that have...

18 CFR 367.57 - Equipment.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Equipment. 367.57 Section 367.57 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT... equipment accounts hand and other portable tools, that are likely to be lost or stolen or that have...

18 CFR 367.57 - Equipment.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Equipment. 367.57 Section 367.57 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT... equipment accounts hand and other portable tools, that are likely to be lost or stolen or that have...

The feasibility of replacing or upgrading utility distribution transformers during routine maintenance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barnes, P.R.; Van Dyke, J.W; McConnell, B.W.

It is estimated that electric utilities use about 40 million distribution transformers in supplying electricity to customers in the United States. Although utility distribution transformers collectively have a high average efficiency, they account for approximately 61 billion kWh of the 229 billion kWh of energy lost annually in the delivery of electricity. Distribution transformers are being replaced over time by new, more efficient, lower-loss units during routine utility maintenance of power distribution systems. Maintenance is typically not performed on units in service. However, units removed from service with appreciable remaining life are often refurbished and returned to stock. Distribution transformersmore » may be removed from service for many reasons, including failure, over- or underloading, or line upgrades such as voltage changes or rerouting. When distribution transformers are removed from service, a decision must be made whether to dispose of the transformer and purchase a lower-loss replacement or to refurbish the transformer and return it to stock for future use. This report contains findings and recommendations on replacing utility distribution transformers during routine maintenance, which is required by section 124 of the Energy Policy Act of 1992. The objectives of the study are to evaluate the practicability, cost-effectiveness, and potential energy savings of replacing or upgrading existing transformers during routine utility maintenance and to develop recommendations on ways to achieve the potential energy savings. Using survey data obtained from utilities and analyses of the economics of refurbishment versus replacement of distribution transformers that are removed from service, it is found that on average utilities are implementing reasonable decisions on refurbishment versus replacement.« less

Water Molecule Hops on Ceres

NASA Image and Video Library

2016-12-15

This graphic shows a theoretical path of a water molecule on Ceres. Some water molecules fall into cold, dark craters at high latitudes called "cold traps," where very little of the ice turns into vapor, even over the course of a billion years. Other water molecules that do not land in cold traps are lost to space as they hop around the dwarf planet. http://photojournal.jpl.nasa.gov/catalog/PIA21083

The Korean-Japanese Territorial Dispute Over Dokdo/Takeshima

DTIC Science & Technology

2007-12-01

Bok-Sook Na, Soon-Sook Na, Soon-Soon Na, Kyung-Sook Na, Jin-Sook Na, and Hye -Jin Na, and twelve nephews and nieces, and my brother-in-law, Han-Il...retreated, and the Japanese won the battle and acquired Dalny, a precious commercial harbor. Japan lost almost 5,000 troops, while the Russians lost...179 Choon-Ho Park , “Oil under Troubled Waters: The Northeast Asia Sea-Bed Controversy,” in East Asia and the Law of the

Method to identify wells that yield water that will be replaced by Colorado River water in Arizona, California, Nevada, and Utah

USGS Publications Warehouse

Wilson, Richard P.; Owen-Joyce, Sandra J.

1994-01-01

Accounting for the use of Colorado River water is required by the U.S. Supreme Court decree, 1964, Arizona v. California. Water pumped from wells on the flood plain and from certain wells on alluvial slopes outside the flood plain is presumed to be river water and is accounted for as Colorado River water. A method was developed to identify wells outside the f1ood plain of the lower Colorado River that yield water that will be replaced by water from the river. The method provides a uniform criterion of identification for all users pumping water from wells. Wells that have a static water-level elevation equal to or below the accounting surface are presumed to yield water that will be replaced by water from the river. Wells that have a static water-level elevation above the accounting surface are presumed to yield water that will be replaced by water from precipitation and inflow from tributary valleys. The method is based on the concept of a river aquifer and an accounting surface within the river aquifer. The river aquifer consists of permeable, partly saturated sediments and sedimentary rocks that are hydraulically connected to the Colorado River so that water can move between the river and the aquifer in response to withdrawal of water from the aquifer or differences in water-level elevations between the river and the aquifer. The accounting surface represents the elevation and slope of the unconfined static water table in the river aquifer outside the flood plain and reservoirs that would exist if the river were the only source of water to the river aquifer. Maps at a scale of 1:100,000 show the extent and elevation of the accounting surface from the area surrounding Lake Mead to Laguna Dam near Yuma, Arizona.

An investigation of water nutrient levels associated with forest vegetation in highly altered landscapes

Treesearch

M.E.G. Golay; J.R. Thompson; C.M. Mabry; R.K. Kolka

2013-01-01

Stream pollution by nutrient loading is a chronic problem in the Midwest, United States, and greater impacts on water quality are expected as agricultural production and urban areas expand. Remnant riparian forests are critical for maintaining ecosystem functions in this landscape context, allowing water infiltration and capture of nutrients before they are lost from...

Universal model for water costs of gas exchange by animals and plants

PubMed Central

Woods, H. Arthur; Smith, Jennifer N.

2010-01-01

For terrestrial animals and plants, a fundamental cost of living is water vapor lost to the atmosphere during exchange of metabolic gases. Here, by bringing together previously developed models for specific taxa, we integrate properties common to all terrestrial gas exchangers into a universal model of water loss. The model predicts that water loss scales to gas exchange with an exponent of 1 and that the amount of water lost per unit of gas exchanged depends on several factors: the surface temperature of the respiratory system near the outside of the organism, the gas consumed (oxygen or carbon dioxide), the steepness of the gradients for gas and vapor, and the transport mode (convective or diffusive). Model predictions were largely confirmed by data on 202 species in five taxa—insects, birds, bird eggs, mammals, and plants—spanning nine orders of magnitude in rate of gas exchange. Discrepancies between model predictions and data seemed to arise from biologically interesting violations of model assumptions, which emphasizes how poorly we understand gas exchange in some taxa. The universal model provides a unified conceptual framework for analyzing exchange-associated water losses across taxa with radically different metabolic and exchange systems. PMID:20404161

Universal model for water costs of gas exchange by animals and plants.

PubMed

Woods, H Arthur; Smith, Jennifer N

2010-05-04

For terrestrial animals and plants, a fundamental cost of living is water vapor lost to the atmosphere during exchange of metabolic gases. Here, by bringing together previously developed models for specific taxa, we integrate properties common to all terrestrial gas exchangers into a universal model of water loss. The model predicts that water loss scales to gas exchange with an exponent of 1 and that the amount of water lost per unit of gas exchanged depends on several factors: the surface temperature of the respiratory system near the outside of the organism, the gas consumed (oxygen or carbon dioxide), the steepness of the gradients for gas and vapor, and the transport mode (convective or diffusive). Model predictions were largely confirmed by data on 202 species in five taxa--insects, birds, bird eggs, mammals, and plants--spanning nine orders of magnitude in rate of gas exchange. Discrepancies between model predictions and data seemed to arise from biologically interesting violations of model assumptions, which emphasizes how poorly we understand gas exchange in some taxa. The universal model provides a unified conceptual framework for analyzing exchange-associated water losses across taxa with radically different metabolic and exchange systems.

High renesting rates in arctic-breeding Dunlin (Calidris alpina): A clutch-removal experiment

USGS Publications Warehouse

Gates, H. River; Lanctot, Richard B.; Powell, Abby N.

2013-01-01

The propensity to replace a clutch is a complex component of avian reproduction and poorly understood. We experimentally removed clutches from an Arctic-breeding shorebird, the Dunlin (Calidris alpina arcticola), during early and late stages of incubation to investigate replacement clutch rates, renesting interval, and mate and site fidelity between nesting attempts. In contrast to other Arctic studies, we documented renesting by radiotracking individuals to find replacement clutches. We also examined clutch size and mean egg volume to document changes in individual females’ investment in initial and replacement clutches. Finally, we examined the influence of adult body mass, clutch volume, dates of clutch initiation and nest loss, and year on the propensity to renest. We found high (82–95%) and moderate (35–50%) rates of renesting for early and late incubation treatments. Renesting intervals averaged 4.7–6.8 days and were not different for clutches removed early or late in incubation. Most pairs remained together for renesting attempts. Larger females were more likely to replace a clutch; female body mass was the most important parameter predicting propensity to renest. Clutches lost later in the season were less likely to be replaced. We present evidence that renesting is more common in Arctic-breeding shorebirds than was previously thought, and suggest that renesting is constrained by energetic and temporal factors as well as mate availability. Obtaining rates of renesting in species breeding at different latitudes will help determine when this behavior is likely to occur; such information is necessary for demographic models that include individual and population-level fecundity estimates.

WATER SUPPLY PIPE REPLACEMENT CONSIDERING SUSTAINABLE TRANSITION TO POPULATION DECREASED SOCIETY

NASA Astrophysics Data System (ADS)

Hosoi, Yoshihiko; Iwasaki, Yoji; Aklog, Dagnachew; Masuda, Takanori

Social infrastructures are aging and population is decreasing in Japan. The aged social infrastructures should be renewed. At the same time, they are required to be moved into new framework suitable for population decreased societies. Furthermore, they have to continue to supply sufficient services even during transition term that renewal projects are carried out. Authors propose sustainable soft landing management of infrastructures and it is tried to apply to water supply pipe replacement in this study. Methodology to replace aged pipes not only aiming for the new water supply network which suits for population decreased condition but also ensuring supply service and feasibility while the project is carried out was developed. It is applied for a model water supply network and discussions were carried out.

Guidelines for replacement of deficient bridges with low-water stream crossings in the rural Midwest : technical summary.

DOT National Transportation Integrated Search

2017-02-01

This report provides guidance to public officials and engineers considering the replacement of a deficient or obsolete bridge with a low-water stream crossing (LWSC). An LWSC is a structure that is occasionally overtopped by floodwaters and is likely...

77 FR 41814 - Entergy Operations, Inc.; Grand Gulf Nuclear Station, Unit 1

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-16

... Unit 1 result primarily from periodic testing of diesel generators and fire water pump diesel engines... rural. GGNS Unit 1 is a General Electric Mark 3 boiling-water reactor. Identification of the Proposed... following: replacing the reactor feed pump turbine rotors; replacing the main generator current transformers...

WATER QUALITY AND THE REPLACEMENT AND REPAIR OF DRINKING WATER INFRASTRUCTURE: THE WASHINGTON, DC CASE STUDY

EPA Science Inventory

A major challenge for society in the 21st century will be replacement, design and optimal management of urban infrastructure. It is estimated that the current world wide demand for infrastructure investment is approximately three trillion US dollars annually. Many developing coun...

EPA Support of Technology Development for Rehabilitation of Wastewater Collection and Water Distribution Systems

EPA Science Inventory

The nation’s 54,000 drinking water systems and 16,000 wastewater systems are nearing the end of their useful life and need to be replaced/repaired to comply with federal regulations. Rehabilitation includes a broad spectrum of approaches, from repair to replacement, that attempt...

Report: American Recovery and Reinvestment Act Site Visit of the Clifton Street Sewer Separation and Water Main Replacement Projects, Portland, Maine

EPA Pesticide Factsheets

Report #11-R-0248, June 7, 2011. We conducted an unannounced site visit of the Clifton Street Sewer Separation and Water Main Replacement Projects in the City of Portland, Maine, from June 15 through June 17, 2009.

Influences of Forest Tree Species and Early Spring Temperature on Surface-Atmosphere Transfers of Water and Carbon in the Northeastern U.S.

NASA Astrophysics Data System (ADS)

Hadley, J. L.; Kuzeja, P.; Mulcahy, T.; Singh, S.

2008-12-01

Influences of Forest Tree Species and Early Spring Temperature on Surface-Atmosphere Transfers of Water and Carbon in the Northeastern U.S. Julian Hadley, Paul Kuzeja, Safina Singh and Thomas Mulcahy Transfers of water vapor from terrestrial ecosystems to the atmosphere affect regional hydrology, weather and climate over short time scales, and forest-atmosphere CO2 exchange affects global climate over long timescales. To better understand these effects for forests dominated by two very different tree species, we measured forest-atmosphere water vapor and CO2 transfers by the eddy flux technique to at two sites in central Massachusetts USA for three years. Average annual evapotranspiration (ET) for a young deciduous forest dominated by red oak (Quercus rubra L., the most abundant tree species in the area), was about 430 mm or 25 percent greater than for a coniferous forest dominated by 100 to 230 year old eastern hemlock (Tsuga canadensis L.). The difference in ET was most pronounced in July and August when the deciduous forest lost about 50 percent more water by ET in the average year (192 mm for oak forest versus 130 mm for hemlock). These data indicate that if deciduous trees with similar physiology to red oak replace hemlocks, summertime ET will increase while summer streamflow, soil water content and the extent of year- round wetlands will decrease. Increased summertime ET should also lead to slightly higher regional atmospheric humidity and precipitation. Hemlock-to-deciduous forest conversion has occurred from North Carolina to southern New England and is continuing northward as a lethal insect pest, the hemlock woolly adelgid (Adelges tsugae Annand) continues to kill hemlocks. Average annual carbon storage for the old hemlock forest in our study was about 3.3 Mg C/ha, nearly equal to the average for the deciduous forest, 3.5 Mg C/ha. This calls into question ecological theory that predicts large declines in the rate of carbon uptake for old forests, and indicates that annual carbon storage will not necessarily increase over the long term after hemlock trees are killed by the hemlock woolly adelgid and replaced by deciduous species. Maximum monthly carbon storage in the hemlock forest occurred in spring (April and May) and was enhanced by early soil thawing and cessation of nighttime frost. This pattern is probably common to many evergreen conifers in the northeastern U.S., so climate warming that includes an earlier end to freezing temperatures in spring should increase C storage by conifer forests in the northeastern U.S. - unless this effect is canceled out by reduced C uptake or enhanced C loss due to changes in summer and fall climate.

The effect on slurry water as a fresh water replacement in concrete properties

NASA Astrophysics Data System (ADS)

Kadir, Aeslina Abdul; Shahidan, Shahiron; Hai Yee, Lau; Ikhmal Haqeem Hassan, Mohd; Bakri Abdullah, Mohd Mustafa Al

2016-06-01

Concrete is the most widely used engineering material in the world and one of the largest water consuming industries. Consequently, the concrete manufacturer, ready mixed concrete plant is increased dramatically due to high demand from urban development project. At the same time, slurry water was generated and leading to environmental problems. Thus, this paper is to investigate the effect of using slurry water on concrete properties in term of mechanical properties. The basic wastewater characterization was investigated according to USEPA (Method 150.1 & 300.0) while the mechanical property of concrete with slurry water was compared according to ASTM C1602 and BS EN 1008 standards. In this research, the compressive strength, modulus of elasticity and tensile strength were studied. The percentage of wastewater replaced in concrete mixing was ranging from 0% up to 50%. In addition, the resulted also suggested that the concrete with 20% replacement of slurry water was achieved the highest compressive strength and modulus of elasticity compared to other percentages. Moreover, the results also recommended that concrete with slurry water mix have better compressive strength compared to control mix concrete.

Effect of fly ash on the strength of porous concrete using recycled coarse aggregate to replace low-quality natural coarse aggregate

NASA Astrophysics Data System (ADS)

Arifi, Eva; Cahya, Evi Nur; Christin Remayanti, N.

2017-09-01

The performance of porous concrete made of recycled coarse aggregate was investigated. Fly ash was used as cement partial replacement. In this study, the strength of recycled aggregate was coMPared to low quality natural coarse aggregate which has high water absorption. Compression strength and tensile splitting strength test were conducted to evaluate the performance of porous concrete using fly ash as cement replacement. Results have shown that the utilization of recycled coarse aggregate up to 75% to replace low quality natural coarse aggregate with high water absorption increases compressive strength and splitting tensile strength of porous concrete. Using fly ash up to 25% as cement replacement improves compressive strength and splitting tensile strength of porous concrete.

Soil water retention within an eroded and restored landscape

USDA-ARS?s Scientific Manuscript database

Significant changes in soil properties and productivity have occurred as a result of intensive row crop production. Many of these changes are related to soil loss from water, wind, and tillage erosion. Soil is lost from convex and steeper landscape positions and deposited in concave lower landscape ...

Improved or unimproved urban areas effect on soil and water quality

USDA-ARS?s Scientific Manuscript database

Construction in urban areas usually results in compacted soil, which restricts plant growth and infiltration. Nutrients may be lost in storm runoff water and sediment. The purpose of this study was to determine if existing lawns benefit from aeration and surface compost additions without negative im...

Development of a River and Stream Water Quality Module

DTIC Science & Technology

2009-06-01

suspended or actively swimming in the water column are referred to as phytoplankton . The term " periphyton " is sometimes used to refer to benthic algae...benthos, and periphyton . ERDC/EL TR-09-4 21 Phytoplankton The phytoplankton biomass increases due to photosynthesis and is lost via respiration...19 Phytoplankton

Ground-water quality in east-central Idaho valleys

USGS Publications Warehouse

Parliman, D.J.

1982-01-01

From May through November 1978, water quality, geologic, and hydrologic data were collected for 108 wells in the Lemhi, Pahsimeroi, Salman River (Stanley to Salmon), Big Lost River, and Little Lost River valleys in east-central Idaho. Data were assembled to define, on a reconnaissance level, water-quality conditions in major aquifers and to develop an understanding of factors that affected conditions in 1978 and could affect future ground-water quality. Water-quality characteristics determined include specific conductance, pH, water temperature, major dissolved cations, major dissolved anions, and coliform bacteria. Concentrations of hardness, nitrite plus nitrate, coliform bacteria, dissolved solids, sulfate, chloride, fluoride , iron, calcium, magnesium, sodium, potassium or bicarbonate exceed public drinking water regulation limits or were anomalously high in some water samples. Highly mineralized ground water probably is due to the natural composition of the aquifers and not to surface contamination. Concentrations of coliform bacteria that exceed public drinking water limits and anomalously high dissolved nitrite-plus-nitrite concentrations are from 15- to 20-year old irrigation wells in heavily irrigated or more densely populated areas of the valleys. Ground-water quality and quantity in most of the study area are sufficient to meet current (1978) population and economic demands. Ground water in all valleys is characterized by significant concentrations of calcium, magnesium, and bicarbonate plus carbonate ions. Variations in the general trend of ground-water composition (especially in the Lemhi Valley) probably are most directly related to variability in aquifer lithology and proximity of sampling site to source of recharge. (USGS)

The corrosive well waters of Egypt's western desert

USGS Publications Warehouse

Clarke, Frank Eldridge

1979-01-01

The discovery that ground waters of Egypt's Western Desert are highly corrosive is lost in antiquity. Inhabitants of the oases have been aware of the troublesome property for many decades and early investigators mention it in their reports concerning the area. Introduction of modern well-drilling techniques and replacements of native wood casing with steel during the 20th century increased corrosion problems and, in what is called the New Valley Project, led to an intense search for causes and corrective treatments. This revealed that extreme corrosiveness results from combined effects of relatively acidic waters with significant concentrations of destructive sulfide ion; unfavorable ratios of sulfate and chloride to less aggressive ions; mineral equilibria and electrode potential which hinder formation of protective films; relative high chemical reaction rates because of abnormal temperatures, and high surface velocities related to well design. There is general agreement among investigators that conventional corrosion control methods such as coating metal surfaces, chemical treatment of the water, and electrolytic protection with impressed current and sacrificial electrodes are ineffective or impracticable for wells in the Western Desert's New Valley. Thus, control must be sought through the use of materials more resistant to corrosion than plain carbon steel wherever well screens and casings are necessary. Of the alternatives considered, stainless steel appears to. be the most promising where high strength and long-term services are required and the alloy's relatively high cost is acceptable. Epoxy resin-bonded fiberglass and wood appear to be practicable, relatively inexpensive alternatives for installations which do. not exceed their strength limitations. Other materials such as high strength aluminum and Monel Metal have shown sufficient promise to. merit their consideration in particular locations and uses. The limited experience with pumping in these desert wells leaves uncertainties concerning the durability of conventional pump designs. Egypt's New Valley Project provides an excellent opportunity for continuing study of the corrosion problems that concern ground-water developers in many parts of the world.

Human impacts on soil carbon dynamics of deep-rooted Amazonian forests

NASA Technical Reports Server (NTRS)

Nepstad, Daniel C.; Stone, Thomas A.; Davidson, Eric A.

1994-01-01

Deforestation and logging degrade more forest in eastern and southern Amazonia than in any other region of the world. This forest alteration affects regional hydrology and the global carbon cycle, but our current understanding of these effects is limited by incomplete knowledge of tropical forest ecosystems. It is widely agreed that roots are concentrated near the soil surface in moist tropical forests, but this generalization incorrectly implies that deep roots are unimportant in water and C budgets. Our results indicate that half of the closed-canopy forests of Brazilian Amazonic occur where rainfall is highly seasonal, and these forests rely on deeply penetrating roots to extract soil water. Pasture vegetation extracts less water from deep soil than the forest it replaces, thus increasing rates of drainage and decreasing rates of evapotranspiration. Deep roots are also a source of modern carbon deep in the soil. The soils of the eastern Amazon contain more carbon below 1 m depth than is present in above-ground biomass. As much as 25 percent of this deep soil C could have annual to decadal turnover times and may be lost to the atmosphere following deforestation. We compared the importance of deep roots in a mature, evergreen forest with an adjacent man-made pasture, the most common type of vegetation on deforested land in Amazonia. The study site is near the town of Paragominas, in the Brazilian state of Para, with a seasonal rainfall pattern and deeply-weathered, kaolinitic soils that are typical for large portions of Amazonia. Root distribution, soil water extraction, and soil carbon dynamics were studied using deep auger holes and shafts in each ecosystem, and the phenology and water status of the leaf canopies were measured. We estimated the geographical distribution of deeply-rooting forests using satellite imagery, rainfall data, and field measurements.

Evaluation of flood inundation in Crystal Springs Creek, Portland, Oregon

USGS Publications Warehouse

Stonewall, Adam; Hess, Glen

2016-05-25

Efforts to improve fish passage have resulted in the replacement of six culverts in Crystal Springs Creek in Portland, Oregon. Two more culverts are scheduled to be replaced at Glenwood Street and Bybee Boulevard (Glenwood/Bybee project) in 2016. Recently acquired data have allowed for a more comprehensive understanding of the hydrology of the creek and the topography of the watershed. To evaluate the impact of the culvert replacements and recent hydrologic data, a Hydrologic Engineering Center-River Analysis System hydraulic model was developed to estimate water-surface elevations during high-flow events. Longitudinal surface-water profiles were modeled to evaluate current conditions and future conditions using the design plans for the culverts to be installed in 2016. Additional profiles were created to compare with the results from the most recent flood model approved by the Federal Emergency Management Agency for Crystal Springs Creek and to evaluate model sensitivity.Model simulation results show that water-surface elevations during high-flow events will be lower than estimates from previous models, primarily due to lower estimates of streamflow associated with the 0.01 and 0.002 annual exceedance probability (AEP) events. Additionally, recent culvert replacements have resulted in less ponding behind crossings. Similarly, model simulation results show that the proposed replacement culverts at Glenwood Street and Bybee Boulevard will result in lower water-surface elevations during high-flow events upstream of the proposed project. Wider culverts will allow more water to pass through crossings, resulting in slightly higher water-surface elevations downstream of the project during high-flows than water-surface elevations that would occur under current conditions. For the 0.01 AEP event, the water-surface elevations downstream of the Glenwood/Bybee project will be an average of 0.05 ft and a maximum of 0.07 ft higher than current conditions. Similarly, for the 0.002 AEP event, the water-surface elevations will be an average of 0.04 ft and a maximum of 0.19 ft higher than current conditions.

Mineral trioxide aggregate pulpotomy in autotransplanted immature mandibular third molar with a 4-year follow-up.

PubMed

Dharmani, Umesh; Jadhav, Ganesh Ranganath; Kaur Dharmani, Charan Kamal; Devi, Takhellambam Premlata

2016-01-01

Autotransplantation is the surgical transposition of a tooth from its original site to another, replacing a lost or a compromised tooth by another tooth, usually the third molar in the same individual. This technique is considered a viable method due to its high success rate, well-grounded treatment option, provided the case selection and the procedure followed is within the acceptable limits. Autotransplantation is considered as an alternative approach of oral rehabilitations in a conservative manner mainly in young patients with compromised financial conditions to perform a high cost treatment. It is a fast way to recover function and aesthetic properties without interfering with the orofacial growth. This report describes a successful 4-year follow-up of a case of immediately performed mineral trioxide aggregate (MTA) pulpotomy in autotransplantated mandibular left immature third molar to replace the mandibular left first molar that was extracted due to extensive carious lesion.

Test Tube Tooth: The Next Big Thing.

PubMed

Yadav, Preeti; Tahir, Mohammed; Yadav, Harsh; Sureka, Rakshit; Garg, Aarti

2016-06-01

Unlike some vertebrates and fishes, humans do not have the capacity for tooth regeneration after the loss of permanent teeth. Although artificial replacement with removable dentures, fixed prosthesis and implants is possible through advances in the field of prosthetic dentistry, it would be ideal to recreate a third set of natural teeth to replace lost dentition. For many years now, researchers in the field of tissue engineering have been trying to bioengineer dental tissues as well as whole teeth. In order to attain a whole tooth through dental engineering, that has the same or nearly same biological, mechanical and physical properties of a natural tooth, it's necessary to deal with all the cells and tissues which are concerned with the formation, maintenance and repair of the tooth. In this article we review the steps involved in odontogenesis or organogenesis of a tooth and progress in the bioengineering of a whole tooth.

Wound-Induced Polyploidization: Regulation by Hippo and JNK Signaling and Conservation in Mammals.

PubMed

Losick, Vicki P; Jun, Albert S; Spradling, Allan C

2016-01-01

Tissue integrity and homeostasis often rely on the proliferation of stem cells or differentiated cells to replace lost, aged, or damaged cells. Recently, we described an alternative source of cell replacement- the expansion of resident, non-dividing diploid cells by wound-induced polyploidization (WIP). Here we show that the magnitude of WIP is proportional to the extent of cell loss using a new semi-automated assay with single cell resolution. Hippo and JNK signaling regulate WIP; unexpectedly however, JNK signaling through AP-1 limits rather than stimulates the level of Yki activation and polyploidization in the Drosophila epidermis. We found that polyploidization also quantitatively compensates for cell loss in a mammalian tissue, mouse corneal endothelium, where increased cell death occurs with age in a mouse model of Fuchs Endothelial Corneal Dystrophy (FECD). Our results suggest that WIP is an evolutionarily conserved homeostatic mechanism that maintains the size and synthetic capacity of adult tissues.

Design, clinical translation and immunological response of biomaterials in regenerative medicine

NASA Astrophysics Data System (ADS)

Sadtler, Kaitlyn; Singh, Anirudha; Wolf, Matthew T.; Wang, Xiaokun; Pardoll, Drew M.; Elisseeff, Jennifer H.

2016-07-01

The field of regenerative medicine aims to replace tissues lost as a consequence of disease, trauma or congenital abnormalities. Biomaterials serve as scaffolds for regenerative medicine to deliver cells, provide biological signals and physical support, and mobilize endogenous cells to repair tissues. Sophisticated chemistries are used to synthesize materials that mimic and modulate native tissue microenvironments, to replace form and to elucidate structure-function relationships of cell-material interactions. The therapeutic relevance of these biomaterial properties can only be studied after clinical translation, whereby key parameters for efficacy can be defined and then used for future design. In this Review, we present the development and translation of biomaterials for two tissue engineering targets, cartilage and cornea, both of which lack the ability to self-repair. Finally, looking to the future, we discuss the role of the immune system in regeneration and the potential for biomaterial scaffolds to modulate immune signalling to create a pro-regenerative environment.

Refinement of habituation procedures in diet-induced obese mice.

PubMed

Kärrberg, L; Andersson, L; Kastenmayer, R J; Ploj, K

2016-10-01

Orogastric gavage, while a common method for delivering experimental substances in mice, has been shown to induce stress. To minimize the associated stress with this procedure, sham gavage prior to the start of experiment is a common method for habiutating mice. We investigated whether handling and restraint could replace sham treatment in the acclimatization protocol. Mice were either undisturbed, hand-restrained for 10 s or sham-gavaged daily for six days prior to eight days of twice daily gavage. The results showed that repetitive restraint and gavage had no differences in body weight after eight days of treatment compared with the body weights at the start of treatment, whereas animals left undisturbed lost significant weight once treatment began. These data suggest that procedure refinement by replacing sham treatment with hand restraint is sufficient to acclimatize mice to the stress associated with gavage. © The Author(s) 2016.

Macrobenthos of Yenisei Bay and the adjacent Kara Sea shelf

NASA Astrophysics Data System (ADS)

Galkin, S. V.; Vedenin, A. A.

2015-07-01

Trawl samples were collected in the northern region of Yenisei Bay and adjacent parts of the Kara Sea shelf. A total of eight stations were taken. We found more than 200 species of benthic organisms. A consecutive replacement of benthic communities is observed when going to the north from the Ob and Yenisei estuaries to the open parts of the sea. We could distinguish four different species complexes in the investigated area: a brackish-water complex where Saduria entomon is dominant; an intermediate complex where S. sibirica, S. sabini and Portlandia aestuariorum are dominant; a transitional complex with P. arctica as a dominant species and with a small amount of Ophiocten sericeum; a marine complex where O. sericeum is dominant. When salinity increased, some brackish-water species were replaced by related euryhaline species. One such example was the replacement of brackish-water Saduria entomon isopods by two euryhaline species: S. sibirica and S. sabini. The consecutive replacement of benthic communities showed a break near Sverdrup Island. In this area the marine complex was replaced by a transitional complex with P. arctica.

Well installation, single-well testing, and particle-size analysis for selected sites in and near the Lost Creek Designated Ground Water Basin, north-central Colorado, 2003-2004

USGS Publications Warehouse

Beck, Jennifer A.; Paschke, Suzanne S.; Arnold, L. Rick

2011-01-01

This report describes results from a groundwater data-collection program completed in 2003-2004 by the U.S. Geological Survey in support of the South Platte Decision Support System and in cooperation with the Colorado Water Conservation Board. Two monitoring wells were installed adjacent to existing water-table monitoring wells. These wells were installed as well pairs with existing wells to characterize the hydraulic properties of the alluvial aquifer and shallow Denver Formation sandstone aquifer in and near the Lost Creek Designated Ground Water Basin. Single-well tests were performed in the 2 newly installed wells and 12 selected existing monitoring wells. Sediment particle size was analyzed for samples collected from the screened interval depths of each of the 14 wells. Hydraulic-conductivity and transmissivity values were calculated after the completion of single-well tests on each of the selected wells. Recovering water-level data from the single-well tests were analyzed using the Bouwer and Rice method because test data most closely resembled those obtained from traditional slug tests. Results from the single-well test analyses for the alluvial aquifer indicate a median hydraulic-conductivity value of 3.8 x 10-5 feet per second and geometric mean hydraulic-conductivity value of 3.4 x 10-5 feet per second. Median and geometric mean transmissivity values in the alluvial aquifer were 8.6 x 10-4 feet squared per second and 4.9 x 10-4 feet squared per second, respectively. Single-well test results for the shallow Denver Formation sandstone aquifer indicate a median hydraulic-conductivity value of 5.4 x 10-6 feet per second and geometric mean value of 4.9 x 10-6 feet per second. Median and geometric mean transmissivity values for the shallow Denver Formation sandstone aquifer were 4.0 x 10-5 feet squared per second and 5.9 x 10-5 feet squared per second, respectively. Hydraulic-conductivity values for the alluvial aquifer in and near the Lost Creek Designated Ground Water Basin generally were greater than hydraulic-conductivity values for the Denver Formation sandstone aquifer and less than hydraulic-conductivity values for the alluvial aquifer along the main stem of the South Platte River Basin reported by previous studies. Particle sizes were analyzed for a total of 14 samples of material representative of the screened interval in each of the 14 wells tested in this study. Of the 14 samples collected, 8 samples represent the alluvial aquifer and 6 samples represent the Denver Formation sandstone aquifer in and near the Lost Creek Designated Ground Water Basin. The sampled alluvial aquifer material generally contained a greater percentage of large particles (larger than 0.5 mm) than the sampled sandstone aquifer material. Alternatively, the sampled sandstone aquifer material generally contained a greater percentage of fine particles (smaller than 0.5 mm) than the sampled alluvial aquifer material consistent with the finding that the alluvial aquifer is more conductive than the sandstone aquifer in the vicinity of the Lost Creek Designated Ground Water Basin.

A study on the performance of concrete containing recycled aggregates and ceramic as materials replacement

NASA Astrophysics Data System (ADS)

Azmi, N. B.; Khalid, F. S.; Irwan, J. M.; Anting, N.; Mazenan, P. N.

2017-11-01

Natural fine aggregate materials are commonly used in development and commercial construction in Malaysia. In fact, concrete production was increased as linear with the growing Malaysia economy. However, an issue was production of concrete was to locate adequate sources of natural fine aggregates. There lot of studies have been conducted in order to replace the fine aggregate in which natural fine aggregate replace with the waste material in concrete preparation. Therefore, this study aims to utilize the Recycled Concrete Aggregate (RCA) and ceramic waste which has great potential to replace the natural aggregate in concrete mix with different type of method, admixture, and parameters. This research were focused on compressive strength and water absorption test to determine the optimum mix ratio of concrete mix. The concrete aggregate was chosen due to improvement capillary bonding mechanisms and ceramic presented similar strength compared to the conventional concrete using natural aggregate. Percent of replacement have been used in this study was at 25%, 35% and 45% of the RCA and 5%, 10% and 15% for ceramic, respectively. Furthermore, this research was conduct to find the optimum percentage of aggregate replacement, using water-cement ratio of 0.55 with concrete grade 25/30. The best percentage of replacement was the RCA35% C15% with the compressive strength of 34.72 MPa and the water absorption was satisfied.

Neuronal replacement therapy: previous achievements and challenges ahead

NASA Astrophysics Data System (ADS)

Grade, Sofia; Götz, Magdalena

2017-10-01

Lifelong neurogenesis and incorporation of newborn neurons into mature neuronal circuits operates in specialized niches of the mammalian brain and serves as role model for neuronal replacement strategies. However, to which extent can the remaining brain parenchyma, which never incorporates new neurons during the adulthood, be as plastic and readily accommodate neurons in networks that suffered neuronal loss due to injury or neurological disease? Which microenvironment is permissive for neuronal replacement and synaptic integration and which cells perform best? Can lost function be restored and how adequate is the participation in the pre-existing circuitry? Could aberrant connections cause malfunction especially in networks dominated by excitatory neurons, such as the cerebral cortex? These questions show how important connectivity and circuitry aspects are for regenerative medicine, which is the focus of this review. We will discuss the impressive advances in neuronal replacement strategies and success from exogenous as well as endogenous cell sources. Both have seen key novel technologies, like the groundbreaking discovery of induced pluripotent stem cells and direct neuronal reprogramming, offering alternatives to the transplantation of fetal neurons, and both herald great expectations. For these to become reality, neuronal circuitry analysis is key now. As our understanding of neuronal circuits increases, neuronal replacement therapy should fulfill those prerequisites in network structure and function, in brain-wide input and output. Now is the time to incorporate neural circuitry research into regenerative medicine if we ever want to truly repair brain injury.

Leaf gas films delay salt entry and enhance underwater photosynthesis and internal aeration of Melilotus siculus submerged in saline water.

PubMed

Teakle, Natasha Lea; Colmer, Timothy David; Pedersen, Ole

2014-10-01

A combination of flooding and salinity is detrimental to most plants. We studied tolerance of complete submergence in saline water for Melilotus siculus, an annual legume with superhydrophobic leaf surfaces that retain gas films when under water. M. siculus survived complete submergence of 1 week at low salinity (up to 50 mol m(-3) NaCl), but did not recover following de-submergence from 100 mol m(-3) NaCl. The leaf gas films protected against direct salt ingress into the leaves when submerged in saline water, enabling underwater photosynthesis even after 3 d of complete submergence. By contrast, leaves with the gas films experimentally removed suffered from substantial Na(+) and Cl(-) intrusion and lost the capacity for underwater photosynthesis. Similarly, plants in saline water and without gas films lost more K(+) than those with intact gas films. This study has demonstrated that leaf gas films reduce Na(+) and Cl(-) ingress into leaves when submerged by saline water - the thin gas layer physically separates the floodwater from the leaf surface. This feature aids survival of plants exposed to short-term saline submergence, as well as the previously recognized beneficial effects of gas exchange under water. © 2014 John Wiley & Sons Ltd.

The molecular basis of neurosensory cell formation in ear development: a blueprint for hair cell and sensory neuron regeneration?

PubMed Central

Fritzsch, Bernd; Beisel, Kirk W.; Hansen, Laura

2014-01-01

Summary The inner ear of mammals uses neurosensory cells derived from the embryonic ear for mechanoelectric transduction of vestibular and auditory stimuli (the hair cells) and conducts this information to the brain via sensory neurons. As with most other neurons of mammals, lost hair cells and sensory neurons are not spontaneously replaced and result instead in age-dependent progressive hearing loss. We review the molecular basis of neurosensory development in the mouse ear to provide a blueprint for possible enhancement of therapeutically useful transformation of stem cells into lost neurosensory cells. We identify several readily available adult sources of stem cells that express, like the ectoderm-derived ear, genes known to be essential for ear development. Use of these stem cells combined with molecular insights into neurosensory cell specification and proliferation regulation of the ear, might allow for neurosensory regeneration of mammalian ears in the near future. PMID:17120192

18 CFR Appendix A to Part 2 - Guidance for Determining the Acceptable Construction Area for Replacements

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Guidance for Determining the Acceptable Construction Area for Replacements A Appendix A to Part 2 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY...

18 CFR Appendix A to Part 2 - Guidance for Determining the Acceptable Construction Area for Replacements

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Guidance for Determining the Acceptable Construction Area for Replacements A Appendix A to Part 2 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY...

18 CFR Appendix A to Part 2 - Guidance for Determining the Acceptable Construction Area for Replacements

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Guidance for Determining the Acceptable Construction Area for Replacements A Appendix A to Part 2 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY...

Chloride Diffusion and Acid Resistance of Concrete Containing Zeolite and Tuff as Partial Replacements of Cement and Sand

PubMed Central

Mohseni, Ehsan; Tang, Waiching; Cui, Hongzhi

2017-01-01

In this paper, the properties of concrete containing zeolite and tuff as partial replacements of cement and sand were studied. The compressive strength, water absorption, chloride ion diffusion and resistance to acid environments of concretes made with zeolite at proportions of 10% and 15% of binder and tuff at ratios of 5%, 10% and 15% of fine aggregate were investigated. The results showed that the compressive strength of samples with zeolite and tuff increased considerably. In general, the concrete strength increased with increasing tuff content, and the strength was further improved when cement was replaced by zeolite. According to the water absorption results, specimens with zeolite showed the lowest water absorption values. With the incorporation of tuff and zeolite, the chloride resistance of specimens was enhanced significantly. In terms of the water absorption and chloride diffusion results, the most favorable replacement of cement and sand was 10% zeolite and 15% tuff, respectively. However, the resistance to acid attack reduced due to the absorbing characteristic and calcareous nature of the tuff. PMID:28772737

The Effect of Non-Uniform Temperature and Velocity Fields on Long Range Ultrasonic Measurement Systems in MYRRHA

NASA Astrophysics Data System (ADS)

Van De Wyer, Nicolas; Schram, Christophe; Van Dyck, Dries; Dierckx, Marc

2017-02-01

SCK·CEN, the Belgian Nuclear Research Center, is developing MYRRHA, a generation IV liquid metal cooled nuclear research reactor. As the liquid metal coolant is opaque to light, normal visual feedback during fuel manipulations is not available and must therefore be replaced by a system that is not hindered by the opacity of the coolant. In this respect ultrasonic based instrumentation is under development at SCK·CEN to provide feedback during operations under liquid metal. One of the tasks that will be tackled using ultrasound is the detection and localization of a potentially lost fuel assembly. The development of this localization tool is detailed in this paper. In this application, the distance between ultrasonic sensor and target may be as large as 2.5m. At these distances, non uniform velocity and temperature fields in the liquid metal potentially influence the propagation of the ultrasonic signals, affecting the performance of the ultrasonic systems. In this paper, we investigate how relevant temperature and velocity gradients inside the liquid metal influence the propagation of ultrasonic waves. The effect of temperature and velocity gradients are simulated by means of a newly developed numerical raytracing model. The performance of the model is validated by dedicated water experiments. The setup is capable of creating velocity and temperature gradients representative for MYRRHA conditions. Once validated in water, the same model is used to make predictions for the effect of gradients in the MYRRHA liquid metal environment.

The development and evaluation of water-mist fire extinguishing systems

NASA Astrophysics Data System (ADS)

Beason, D. G.; Staggs, K. J.

1994-08-01

Fire protection for underfloor space is primarily provided by Halon 1301 which has proven to be very effective. However, due to the link between halons and the possible depletion of the stratospheric ozone layer, plans have been implemented to eventually phase out Halon 1301 and 1211. In September 1987 the Montreal Protocol concerning chlorofluorocarbons (CFC) and halons was signed by the United States, the European Economic Community, and 23 other nations. The Montreal Protocol calls for freezing halon production at 1986 levels. Because the majority of underfloor fire protection at Lawrence Livermore National Laboratory (LLNL), as well as other Department of Energy (DOE) sites, is either Halon 1301 or sprinklers, some other means of suppression will have to be developed and verified. The potential loss to facilities housing computer or control rooms damaged by underfloor fires can be extreme. These losses would not only include hardware and software replacement costs, but also lost computing and control capability. Here at LLNL technical research in a facility could be severely affected. Recent studies conducted by the Fire Research Discipline of the Special Projects Division have shown that severe fires fueled by cable insulation can develop within as little as a 6-in-high underfloor space (even with mechanical ventilation shut off). Studies also show that conventional sprinklers may not be effective in preventing this destruction. Therefore, we are investigating the water-mist fire extinguishing system as an alternative to Halon 1301 and sprinklers.

Production of Tuber-Inducing Factor

NASA Technical Reports Server (NTRS)

Stutte, Gary W.; Yorio, Neil C.

2006-01-01

A process for making a substance that regulates the growth of potatoes and some other economically important plants has been developed. The process also yields an economically important by-product: potatoes. The particular growth-regulating substance, denoted tuber-inducing factor (TIF), is made naturally by, and acts naturally on, potato plants. The primary effects of TIF on potato plants are reducing the lengths of the main shoots, reducing the numbers of nodes on the main stems, reducing the total biomass, accelerating the initiation of potatoes, and increasing the edible fraction (potatoes) of the overall biomass. To some extent, these effects of TIF can override environmental effects that typically inhibit the formation of tubers. TIF can be used in the potato industry to reduce growth time and increase harvest efficiency. Other plants that have been observed to be affected by TIF include tomatoes, peppers, radishes, eggplants, marigolds, and morning glories. In the present process, potatoes are grown with their roots and stolons immersed in a nutrient solution in a recirculating hydroponic system. From time to time, a nutrient replenishment solution is added to the recirculating nutrient solution to maintain the required nutrient concentration, water is added to replace water lost from the recirculating solution through transpiration, and an acid or base is added, as needed, to maintain the recirculating solution at a desired pH level. The growing potato plants secrete TIF into the recirculating solution. The concentration of TIF in the solution gradually increases to a range in which the TIF regulates the growth of the plants.

Water-deuterium oxide exchange in polymers used in spacecraft applications. [outgassing from Mylar and Kapton

NASA Technical Reports Server (NTRS)

Carre, D. J.

1980-01-01

The replacement of water (H2O) by deuterium oxide (D2O) and the exchange between atmospheric water and adsorbed or absorbed D2O were investigated for the polymeric materials Kapton and Mylar using thermal gravimetric analysis and infrared spectroscopy. Replacement of H2O by D2O is easily accomplished. However, exposure of D2O samples to the ambient atmosphere or gases containing H2O results in rapid proton and deuteron exchange between H2O vapor and adsorbed D2O. Replacement of H2O by D2O would not be a practical solution to alleviate spectral interferences that would result from water outgassing in spacecraft orbital environments. Maintaining the materials of interest in a dehydrated state is a more reasonable approach.

South Atlantic circulation in a world ocean model

NASA Astrophysics Data System (ADS)

England, Matthew H.; Garçon, Véronique C.

1994-09-01

The circulation in the South Atlantic Ocean has been simulated within a global ocean general circulation model. Preliminary analysis of the modelled ocean circulation in the region indicates a rather close agreement of the simulated upper ocean flows with conventional notions of the large-scale geostrophic currents in the region. The modelled South Atlantic Ocean witnesses the return flow and export of North Atlantic Deep Water (NADW) at its northern boundary, the inflow of a rather barotropic Antarctic Circumpolar Current (ACC) through the Drake Passage, and the inflow of warm saline Agulhas water around the Cape of Good Hope. The Agulhas leakage amounts to 8.7 Sv, within recent estimates of the mass transport shed westward at the Agulhas retroflection. Topographic steering of the ACC dominates the structure of flow in the circumpolar ocean. The Benguela Current is seen to be fed by a mixture of saline Indian Ocean water (originating from the Agulhas Current) and fresher Subantarctic surface water (originating in the ACC). The Benguela Current is seen to modify its flow and fate with depth; near the surface it flows north-westwards bifurcating most of its transport northward into the North Atlantic Ocean (for ultimate replacement of North Atlantic surface waters lost to the NADW conveyor). Deeper in the water column, more of the Benguela Current is destined to return with the Brazil Current, though northward flows are still generated where the Benguela Current extension encounters the coast of South America. At intermediate levels, these northward currents trace the flow of Antarctic Intermediate Water (AAIW) equatorward, though even more AAIW is seen to recirculate poleward in the subtropical gyre. In spite of the model's rather coarse resolution, some subtle features of the Brazil-Malvinas Confluence are simulated rather well, including the latitude at which the two currents meet. Conceptual diagrams of the recirculation and interocean exchange of thermocline, intermediate and deep waters are constructed from an analysis of flows bound between isothermal and isobaric surfaces. This analysis shows how the return path of NADW is partitioned between a cold water route through the Drake Passage (6.5 Sv), a warm water route involving the Agulhas Current sheeding thermocline water westward (2.5 Sv), and a recirculation of intermediate water originating in the Indian Ocean (1.6 Sv).

The use of inulin as fat replacer and its effect on texture and sensory properties of emulsion type sausages

PubMed Central

Berizi, E.; Shekarforoush, S. S.; Mohammadinezhad, S.; Hosseinzadeh, S.; Farahnaki, A.

2017-01-01

The present study aimed to investigate the possibility of reducing energy content in emulsion type sausages by replacing fat with inulin. In the manufactured product, the fat content was reduced to 6%-18% and replaced by inulin and water. The quality of the resulting product was determined by chemical and texture profile analyses (TPA), color measurement and sensory evaluation. The results showed that replacing fat with inulin led to a significant energy content reduction of up to 64% (with 6% inulin and 12% water). In addition, color measurement, sensory evaluation and TPA were comparable to the traditional product in the inulin treated samples. The overall acceptability of all experimental groups was adequate; therefore, inulin is suggested as a good replacement for fat in emulsion type sausages. PMID:29387097

The use of inulin as fat replacer and its effect on texture and sensory properties of emulsion type sausages.

PubMed

Berizi, E; Shekarforoush, S S; Mohammadinezhad, S; Hosseinzadeh, S; Farahnaki, A

2017-01-01

The present study aimed to investigate the possibility of reducing energy content in emulsion type sausages by replacing fat with inulin. In the manufactured product, the fat content was reduced to 6%-18% and replaced by inulin and water. The quality of the resulting product was determined by chemical and texture profile analyses (TPA), color measurement and sensory evaluation. The results showed that replacing fat with inulin led to a significant energy content reduction of up to 64% (with 6% inulin and 12% water). In addition, color measurement, sensory evaluation and TPA were comparable to the traditional product in the inulin treated samples. The overall acceptability of all experimental groups was adequate; therefore, inulin is suggested as a good replacement for fat in emulsion type sausages.

Coconut Water

MedlinePlus

... before exercise to prevent dehydration. Coconut water might work better than drinking plain water, but results are still preliminary. Exercise performance. Some athletes use coconut water to replace fluids ...

Oral salt supplements to compensate for jejunostomy losses: comparison of sodium chloride capsules, glucose electrolyte solution, and glucose polymer electrolyte solution.

PubMed

Nightingale, J M; Lennard-Jones, J E; Walker, E R; Farthing, M J

1992-06-01

Six patients with jejunostomies and residual jejunal lengths of 105 to 250 cm took the same food and water each day for eight study days. In random order, three methods of salt replacement were tested, each over 48 hours, against a period without added salt. During the three test periods the patients took 120 mmol of sodium chloride daily, as salt in gelatine capsules, as an isotonic glucose electrolyte (280 mOsmol/kg; 30 kcal) solution, and as a glucose polymer (Maxijul) solution (280 mOsmol/kg; 200 kcal). The daily stomal output remained constant for each patient during the four test periods but varied between patients from 0.60 to 2.84 kg (daily intestinal fluid balance 0.74-2.61 kg). Without a salt supplement, three patients lost more sodium from the stoma than they took in by mouth (-25, -94, and -101 mmol/day) and the mean sodium balance for all six subjects was -16 mmol (range -101 to 79) daily. Extra salt was absorbed with each form of supplement (p less than 0.05); no patient with the glucose electrolyte solution (mean 96, range 0 to 226 mmol), but one patient with the glucose-polymer solution (mean 96, range -25 to 164 mmol) and two with the salt capsules (mean 66, range -8 to 145 mmol) were in negative balance. Two patients vomited with the salt capsules. There was only a small increase in energy absorption (mean 115 kcal) with the glucose polymer solution compared with the glucose electrolyte solution. A sipped glucose electrolyte solution seems to be the optimal mode of sodium replacement in patients with a high output jejunostomy.

Oral salt supplements to compensate for jejunostomy losses: comparison of sodium chloride capsules, glucose electrolyte solution, and glucose polymer electrolyte solution.

PubMed Central

Nightingale, J M; Lennard-Jones, J E; Walker, E R; Farthing, M J

1992-01-01

Six patients with jejunostomies and residual jejunal lengths of 105 to 250 cm took the same food and water each day for eight study days. In random order, three methods of salt replacement were tested, each over 48 hours, against a period without added salt. During the three test periods the patients took 120 mmol of sodium chloride daily, as salt in gelatine capsules, as an isotonic glucose electrolyte (280 mOsmol/kg; 30 kcal) solution, and as a glucose polymer (Maxijul) solution (280 mOsmol/kg; 200 kcal). The daily stomal output remained constant for each patient during the four test periods but varied between patients from 0.60 to 2.84 kg (daily intestinal fluid balance 0.74-2.61 kg). Without a salt supplement, three patients lost more sodium from the stoma than they took in by mouth (-25, -94, and -101 mmol/day) and the mean sodium balance for all six subjects was -16 mmol (range -101 to 79) daily. Extra salt was absorbed with each form of supplement (p less than 0.05); no patient with the glucose electrolyte solution (mean 96, range 0 to 226 mmol), but one patient with the glucose-polymer solution (mean 96, range -25 to 164 mmol) and two with the salt capsules (mean 66, range -8 to 145 mmol) were in negative balance. Two patients vomited with the salt capsules. There was only a small increase in energy absorption (mean 115 kcal) with the glucose polymer solution compared with the glucose electrolyte solution. A sipped glucose electrolyte solution seems to be the optimal mode of sodium replacement in patients with a high output jejunostomy. PMID:1624155

Evaluation of pressurized water cleaning systems for hardware refurbishment

NASA Technical Reports Server (NTRS)

Dillard, Terry W.; Deweese, Charles D.; Hoppe, David T.; Vickers, John H.; Swenson, Gary J.; Hutchens, Dale E.

1995-01-01

Historically, refurbishment processes for RSRM motor cases and components have employed environmentally harmful materials. Specifically, vapor degreasing processes consume and emit large amounts of ozone depleting compounds. This program evaluates the use of pressurized water cleaning systems as a replacement for the vapor degreasing process. Tests have been conducted to determine if high pressure water washing, without any form of additive cleaner, is a viable candidate for replacing vapor degreasing processes. This paper discusses the findings thus far of Engineering Test Plan - 1168 (ETP-1168), 'Evaluation of Pressurized Water Cleaning Systems for Hardware Refurbishment.'

Genetic engineered color silk: fabrication of a photonics material through a bioassisted technology.

PubMed

Shimizu, Katsuhiko

2018-05-15

Silk produced by the silkworm Bombyx mori is an attractive material because of its luster, smooth and soft texture, conspicuous mechanical strength, good biocompatibility, slow biodegradation, and carbon neutral synthesis. Silkworms have been domesticated and bred for production of better quality and quantity of silk, resulting in the development of sericulture and the textile industry. Silk is generally white, so dyeing is required to obtain colored fiber. However, the dyeing process involves harsh conditions and generates a large volume of waste water, which have environmentally and economically negative impacts. Although some strains produce cocoons that contain pigments derived from the mulberry leaves that they eat, the pigments are distributed in the sericin layer and are lost during gumming. In trials for production of colored silk by feeding silkworms on diets containing dyes, only limited species of dye molecules were incorporated into the silk threads. A method for the generation of transgenic silkworm was established in conjunction with the discovery of green fluorescent protein (GFP), and silkworms carrying the GFP gene spun silk threads that formed cocoons that glowed bright green and still retained the original properties of silk. A wide range of color variation of silk threads has been obtained by replacing the GFP gene with the genes of other fluorescent proteins chosen from the fluorescent protein palette. The genetically modified silk with photonic properties can be processed to form various products including linear threads, 2D fabrics, and 3D materials. The transgenic colored silk could be economically advantageous due to addition of a new value to silk and reduction of cost for water waste, and environmentally preferable for saving water. Here, I review the literature regarding the production methods of fluorescent silk from transgenic silkworms and present examples of genetically modified color silk.

Towards new-generation soil erosion modeling: Building a unified omnivorous model

USDA-ARS?s Scientific Manuscript database

Soil erosion is a global threat to agricultural production, and results in off-site sediment and nutrient losses that negatively impact water and air quality. Models are mathematical equations used to estimate the amount of soil lost from a land air, due to the erosive forces of water or wind. Early...

Deeply-sourced formate fuels sulfate reducers but not methanogens at Lost City hydrothermal field.

PubMed

Lang, Susan Q; Früh-Green, Gretchen L; Bernasconi, Stefano M; Brazelton, William J; Schrenk, Matthew O; McGonigle, Julia M

2018-01-15

Hydrogen produced during water-rock serpentinization reactions can drive the synthesis of organic compounds both biotically and abiotically. We investigated abiotic carbon production and microbial metabolic pathways at the high energy but low diversity serpentinite-hosted Lost City hydrothermal field. Compound-specific 14 C data demonstrates that formate is mantle-derived and abiotic in some locations and has an additional, seawater-derived component in others. Lipids produced by the dominant member of the archaeal community, the Lost City Methanosarcinales, largely lack 14 C, but metagenomic evidence suggests they cannot use formate for methanogenesis. Instead, sulfate-reducing bacteria may be the primary consumers of formate in Lost City chimneys. Paradoxically, the archaeal phylotype that numerically dominates the chimney microbial communities appears ill suited to live in pure hydrothermal fluids without the co-occurrence of organisms that can liberate CO 2 . Considering the lack of dissolved inorganic carbon in such systems, the ability to utilize formate may be a key trait for survival in pristine serpentinite-hosted environments.

Making up for lost snow: lessons from a warming Sierra Nevada

NASA Astrophysics Data System (ADS)

Bales, R. C.

2017-12-01

Snowpack- and glacier-dependent river basins are home to over 1.2 billion people, one-sixth of the world's current population. These areas face severe challenges in a warmer climate, as declines in snow resources put more pressure on dams and groundwater. Closer to home, the seasonal snowpacks in California's Sierra Nevada provide water storage to both sustain productive forests and support the world's 6th largest economy. Rivers draining the Sierra supply the state's large cities, plus agricultural areas that provide nearly half of the nation's fruits and vegetables. Water storage is central to water security, especially given California's hot dry summers and high interannual variability in precipitation. On average seasonal snowpacks store about half as much water as do dams on Sierra rivers; and both the magnitude and duration of snowpack storage are decreasing. Precipitation amount and snow accumulation across the mountains in any given day, month or year remain uncertain. As historical index-statistical methods for hydrologic forecasts give way to tools based on mass and energy balances distributed across the landscape, opportunities are arising to broadly implement spatial measurements of snowpack storage and the equally important regolith-water storage. Advances in applying satellite and aircraft remote sensing, plus spatially distributed wireless-sensor networks, are filling this need. These same unprecedented data are driving process understanding to improve knowledge of snow-energy-forest interactions, snowmelt estimates, and hydrologic forecasts for hydropower, water supply, and flood control. Estimating the value of snowpacks and how they are changing provides a baseline for evaluating investments in restoration of headwater forests that will affect snowmelt runoff, and in providing replacement storage as snow declines. With California facing billions of dollars of green and grey infrastructure improvements, which must be compatible with the state's aggressive carbon-neutrality goals, it is critical to build support for expenditures. Science communication featuring Sierra Nevada snow through written, broadcast and film media can enhance public understanding and provide a basis for infrastructure and operational investments to address water security in a changing climate.

The fate of early Mars' lost water: The role of serpentinization

NASA Astrophysics Data System (ADS)

ChassefièRe, Eric; Langlais, Benoit; Quesnel, Yoann; Leblanc, FrançOis

2013-05-01

The fate of water which was present on early Mars remains enigmatic. We propose a simple model based on serpentinization, a hydrothermal alteration process which may produce magnetite and store water. Our model invokes serpentinization during about 500 to 800 Myr, while a dynamo is active, which may have continued after the formation of the crustal dichotomy. We show that the present magnetic field measured by Mars Global Surveyor in the southern hemisphere is consistent with a ~500 m thick Global Equivalent Layer (GEL) of water trapped in serpentine. Serpentinization results in the release of H2. The released H atoms are lost to space through thermal escape, increasing the D/H ratio in water reservoirs exchanging with atmosphere. We show that the value of the D/H ratio in the present atmosphere (~5) is also consistent with the serpentinization of a ~500 m thick water GEL. We reassess the role of nonthermal escape in removing water from the planet. By considering an updated solar wind-ionosphere interaction representation, we show that the contribution of oxygen escape to H isotopic fractionation is negligible. Our results suggest that significant amounts of water (up to a ~330-1030 m thick GEL) present at the surface during the Noachian, similar to the quantity inferred from the morphological analysis of valley networks, could be stored today in subsurface serpentine.

18 CFR Appendix A to Part 2 - Guidance for Determining the Acceptable Construction Area for Auxiliary and Replacement Facilities

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Guidance for Determining the Acceptable Construction Area for Auxiliary and Replacement Facilities A Appendix A to Part 2 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL...

Two-dimensional streamflow simulations of the Jordan River, Midvale and West Jordan, Utah

USGS Publications Warehouse

Kenney, Terry A.; Freeman, Michael L.

2011-01-01

The Jordan River in Midvale and West Jordan, Utah, flows adjacent to two U.S. Environmental Protection Agency Superfund sites: Midvale Slag and Sharon Steel. At both sites, geotechnical caps extend to the east bank of the river. The final remediation tasks for these sites included the replacement of a historic sheet-pile dam and the stabilization of the river banks adjacent to the Superfund sites. To assist with these tasks, two hydraulic modeling codes contained in the U.S. Geological Survey (USGS) Multi-Dimensional Surface-Water Modeling System (MD_SWMS), System for Transport and River Modeling (SToRM) and Flow and Sediment Transport and Morphological Evolution of Channels (FaSTMECH), were used to provide predicted water-surface elevations, velocities, and boundary shear-stress values throughout the study reach of the Jordan River. A SToRM model of a 0.7 mile subreach containing the sheet-pile dam was used to compare water-surface elevations and velocities associated with the sheet-pile dam and a proposed replacement structure. Maps showing water-surface elevation and velocity differences computed from simulations of the historic sheet-pile dam and the proposed replacement structure topographies for streamflows of 500 and 1,000 cubic feet per second (ft3/s) were created. These difference maps indicated that the velocities associated with the proposed replacement structure topographies were less than or equal to those associated with the historic sheet-pile dam. Similarly, water-surface elevations associated with the proposed replacement structure topographies were all either greater than or equal to water-surface elevations associated with the sheet-pile dam. A FaSTMECH model was developed for the 2.5-mile study reach to aid engineers in bank stabilization designs. Predicted water-surface elevations, velocities and shear-stress values were mapped on an aerial photograph of the study reach to place these parameters in a spatial context. Profile plots of predicted cross-stream average water-surface elevations and cross-stream maximum and average velocities showed how these parameters change along the study reach for two simulated discharges of 1,040 ft3/s and 2,790 ft3/s. The profile plots for the simulated streamflow of 1,040 ft3/s show that the highest velocities are associated with the constructed sheet-pile replacement structure. Results for the simulated streamflow of 2,790 ft3/s indicate that the geometry of the 7800 South Bridge causes more backwater and higher velocities than the constructed sheet-pile replacement structure.

A Water Rehabilitation Program in Patients with Hip Osteoarthritis Before and After Total Hip Replacement.

PubMed

Łyp, Marek; Kaczor, Ryszard; Cabak, Anna; Tederko, Piotr; Włostowska, Ewa; Stanisławska, Iwona; Szypuła, Jan; Tomaszewski, Wiesław

2016-07-25

BACKGROUND Pain associated with coxarthrosis, typically occurring in middle-aged and elderly patients, very commonly causes considerable limitation of motor fitness and dependence on pharmacotherapy. This article provides an assessment of a rehabilitation program with tailored water exercises in patients with osteoarthritis before and after total hip replacement. MATERIAL AND METHODS A total of 192 patients (the mean age 61.03±10.89) suffering from hip osteoarthritis (OA) were evaluated before and after total hip replacement (THR). The clinical study covered measurements of hip active ranges of motion (HAROM) and the forces generated by pelvis stabilizer muscles. Pain intensity was assessed according to analogue-visual scale of pain (VAS) and according to the Modified Laitinen Questionnaire. The patients were divided into 6 groups (4 treatment and 2 control). We compared 2 rehabilitation programs using kinesitherapy and low-frequency magnetic field. One of them also had specially designed exercises in the water. Statistical analysis was carried out at the significance level α=0.05. This was a cross-sectional study. RESULTS A positive effect of water exercises on a number of parameters was found in patients with OA both before and after total hip replacement surgery. We noted a significant reduction of pain (p<0.001), increased ranges of motion and muscle strength, and reduced use of medicines (NASAIDs) (p<0.001). A correlation was found between the degree of degenerative deforming lesions and the effects of the treatment process (p<0.01). CONCLUSIONS 1. The rehabilitation program including water exercises most significantly reduced pain in patients with OA before and after total hip replacement surgery. 2. Inclusion of water exercises in a rehabilitation program can reduce the use of medicines in patient with OA and after THR.

Inter-annual variability in apparent relative production, survival, and growth of juvenile Lost River and shortnose suckers in Upper Klamath Lake, Oregon, 2001–15

USGS Publications Warehouse

Burdick, Summer M.; Martin, Barbara A.

2017-06-15

Executive SummaryPopulations of the once abundant Lost River (Deltistes luxatus) and shortnose suckers (Chasmistes brevirostris) of the Upper Klamath Basin, decreased so substantially throughout the 20th century that they were listed under the Endangered Species Act in 1988. Major landscape alterations, deterioration of water quality, and competition with and predation by exotic species are listed as primary causes of the decreases in populations. Upper Klamath Lake populations are decreasing because fish lost due to adult mortality, which is relatively low for adult Lost River suckers and variable for adult shortnose suckers, are not replaced by new young adult suckers recruiting into known adult spawning aggregations. Catch-at-age and size data indicate that most adult suckers presently in Upper Klamath Lake spawning populations were hatched around 1991. While, a lack of egg production and emigration of young fish (especially larvae) may contribute, catch-at-length and age data indicate high mortality during the first summer or winter of life may be the primary limitation to the recruitment of young adults. The causes of juvenile sucker mortality are unknown.We compiled and analyzed catch, length, age, and species data on juvenile suckers from Upper Klamath Lake from eight prior studies conducted from 2001 to 2015 to examine annual variation in apparent production, survival, and growth of young suckers. We used a combination of qualitative assessments, general linear models, and linear regression to make inferences about annual differences in juvenile sucker dynamics. The intent of this exercise is to provide information that can be compared to annual variability in environmental conditions with the hopes of understanding what drives juvenile sucker population dynamics.Age-0 Lost River suckers generally grew faster than age-0 shortnose suckers, but the difference in growth rates between the two species varied among years. This unsynchronized annual variation in daily growth may be an indication that environmental conditions are affecting growth rates of these species in different ways.The combined evidence outlined in this report and in Simon and others (2012) indicates that years of relatively high age-0 sucker production occurred in the late 1990s through at least 2000, in 2006, and in 2011. Our analysis of annual age-0 sucker catch per unit effort (CPUE), which accounted for zero inflated data and annual variation in sampling gears and locations, indicated that 2006 had the greatest apparent relative production of age-0 suckers ≥ 45 mm standard length (SL) during the time period examined. Midsummer trap net effort by the U.S. Geological Survey (USGS) was too sparse to examine age-0 sucker CPUE from 2011 to 2013. Relatively frequent catches of age-1 suckers in 2001, 2007, and 2012 corroborated relatively high CPUE for age-0 suckers during 1999–2000, 2006, and 2011, as reported by USGS or Simon and others (2012).There were several indications in the data that juvenile sucker survival is low from at least midsummer of the first year of life through mid-September of the second year of life. Our estimated index of relative apparent age-0 sucker late-summer survival, which accounted for zero inflated data and variations in sampling gears and locations, was higher in 2009 than in 2004. Our index of apparent age-0 sucker mortality for all other years from 2001 to 2015 was similar among years. Seventy-five percent of age-1 suckers were captured prior to July 17 each year. In 2007, the one year with substantial age-1 sucker summertime catches, the proportion of nets to capture age-1 suckers decreased from July to mid-September. Maximum annual age-2+ sucker CPUE was 0.02 fish per net, 10,000 times less than the maximum annual age-0 sucker CPUE.Analysis of species data indicated that juvenile Lost River suckers may have greater apparent mortality than shortnose suckers. Lost River suckers made up a smaller proportion of age-0 suckers captured in July each year than would be expected, based on the abundance of adult Lost River suckers relative to shortnose suckers, and higher Lost River than shortnose sucker fecundity. The proportion of age-0 suckers captured that were Lost River suckers decreased from July to September in several years. Only 14 percent of age-1 or older juvenile suckers identified to species over the 15-year time period were Lost River suckers.

Periodontal Bioengineering: A Discourse in Surface Topographies, Progenitor Cells and Molecular Profiles

NASA Astrophysics Data System (ADS)

Dangaria, Smit J.

2011-12-01

Stem/progenitor cells are a population of cells capable of providing replacement cells for a given differentiated cell type. We have applied progenitor cell-based technologies to generate novel tissue-engineered implants that use biomimetic strategies with the ultimate goal of achieving full regeneration of lost periodontal tissues. Mesenchymal periodontal tissues such as cementum, alveolar bone (AB), and periodontal ligament (PDL) are neural crest-derived entities that emerge from the dental follicle (DF) at the onset of tooth root formation. Using a systems biology approach we have identified key differences between these periodontal progenitors on the basis of global gene expression profiles, gene cohort expression levels, and epigenetic modifications, in addition to differences in cellular morphologies. On an epigenetic level, DF progenitors featured high levels of the euchromatin marker H3K4me3, whereas PDL cells, AB osteoblasts, and cementoblasts contained high levels of the transcriptional repressor H3K9me3. Secondly, we have tested the influence of natural extracellular hydroxyapatite matrices on periodontal progenitor differentiation. Dimension and structure of extracellular matrix surfaces have powerful influences on cell shape, adhesion, and gene expression. Here we show that natural tooth root topographies induce integrin-mediated extracellular matrix signaling cascades in tandem with cell elongation and polarization to generate physiological periodontium-like tissues. In this study we replanted surface topography instructed periodontal ligament progenitors (PDLPs) into rat alveolar bone sockets for 8 and 16 weeks, resulting in complete attachment of tooth roots to the surrounding alveolar bone with a periodontal ligament fiber apparatus closely matching physiological controls along the entire root surface. Displacement studies and biochemical analyses confirmed that progenitor-based engineered periodontal tissues were similar to control teeth and uniquely derived from pre-implantation green fluorescent protein (GFP)-labeled progenitors. Together, these studies illustrate the capacity of natural extracellular surface topographies to instruct PDLPs to fully regenerate complex cellular and structural morphologies of tissues once lost to disease. We suggest that our strategy could be used for the replantation of teeth lost due to trauma or as a novel approach for tooth replacement using tooth-shaped replicas.

Evaluation of internal loading and water level changes: implications for phosphorus, algal production, and nuisance blooms in Kabetogama Lake, Voyageurs National Park, Minnesota

USGS Publications Warehouse

Christensen, Victoria G.; Maki, Ryan P.; Kiesling, Richard L.

2013-01-01

Hydrologic manipulations have the potential to exacerbate or remediate eutrophication in productive reservoirs. Dam operations at Kabetogama Lake, Minnesota, were modified in 2000 to restore a more natural water regime and improve water quality. The US Geological Survey and National Park Service evaluated nutrient, algae, and nuisance bloom data in relation to changes in Kabetogama Lake water levels. Comparison of the results of this study to previous studies indicates that chlorophyll a concentrations have decreased, whereas total phosphorus (TP) concentrations have not changed significantly since 2000. Water and sediment quality data were collected at Voyageurs National Park during 2008–2009 to assess internal phosphorus loading and determine whether loading is a factor affecting TP concentrations and algal productivity. Kabetogama Lake often was mixed vertically, except for occasional stratification measured in certain areas, including Lost Bay in the northeastern part of Kabetogama Lake. Stratification, higher bottom water and sediment nutrient concentrations than in other parts of the lake, and phosphorus release rates estimated from sediment core incubations indicated that Lost Bay is one of several areas that may be contributing to internal loading. Internal loading of TP is a concern because increased TP may cause excessive algal growth including potentially toxic cyanobacteria.

The use of stem cells in regenerative medicine for Parkinson's and Huntington's Diseases.

PubMed

Lescaudron, L; Naveilhan, P; Neveu, I

2012-01-01

Cell transplantation has been proposed as a means of replacing specific cell populations lost through neurodegenerative processes such as that seen in Parkinson's or Huntington's diseases. Improvement of the clinical symptoms has been observed in a number of Parkinson and Huntington's patients transplanted with freshly isolated fetal brain tissue but such restorative approach is greatly hampered by logistic and ethical concerns relative to the use of fetal tissue, in addition to potential side effects that remain to be controlled. In this context, stem cells that are capable of self-renewal and can differentiate into neurons, have received a great deal of interest, as demonstrated by the numerous studies based on the transplantation of neural stem/progenitor cells, embryonic stem cells or mesenchymal stem cells into animal models of Parkinson's or Huntington's diseases. More recently, the induction of pluripotent stem cells from somatic adult cells has raised a new hope for the treatment of neurodegenerative diseases. In the present article, we review the main experimental approaches to assess the efficiency of cell-based therapy for Parkinson's or Huntington's diseases, and discuss the recent advances in using stem cells to replace lost dopaminergic mesencephalic or striatal neurons. Characteristics of the different stem cells are extensively examined with a special attention to their ability of producing neurotrophic or immunosuppressive factors, as these may provide a favourable environment for brain tissue repair and long-term survival of transplanted cells in the central nervous system. Thus, stem cell therapy can be a valuable tool in regenerative medicine.

Ex vivo and in vitro synchrotron-based micro-imaging of biocompatible materials applied in dental surgery

NASA Astrophysics Data System (ADS)

Rack, A.; Stiller, M.; Nelson, K.; Knabe, C.; Rack, T.; Zabler, S.; Dalügge, O.; Riesemeier, H.; Cecilia, A.; Goebbels, J.

2010-09-01

Biocompatible materials such as porous bioactive calcium phosphate ceramics or titanium are regularly applied in dental surgery: ceramics are used to support the local bone regeneration in a given defect, afterwards titanium implants replace lost teeth. The current gold standard for bone reconstruction in implant dentistry is the use of autogenous bone grafts. But the concept of guided bone regeneration (GBR) has become a predictable and well documented surgical approach using biomaterials (bioactive calcium phosphate ceramics) which qualify as bone substitutes for this kind of application as well. We applied high resolution synchrotron microtomography and subsequent 3d image analysis in order to investigate bone formation and degradation of the bone substitute material in a three-dimensional manner, extending the knowledge beyond the limits of classical histology. Following the bone regeneration, titanium-based implants to replace lost teeth call for high mechanical precision, especially when two-piece concepts are used in order to guaranty leak tightness. Here, synchrotron-based radiography in comparison with classical laboratory radiography yields high spatial resolution in combination with high contrast even when exploiting micro-sized features in these kind of highly attenuating objects. Therefore, we could study micro-gap formation at interfaces in two-piece dental implants with the specimen under different mechanical load. We could prove the existence of micro-gaps for implants with conical connections as well as to study the micromechanical behavior of the mating zone of conical implants during loading. The micro-gap is a potential issue of failure, i. e. bacterial leakage which can induce an inflammatory process.

One-year weight losses in the Look AHEAD study: factors associated with success.

PubMed

Wadden, Thomas A; West, Delia S; Neiberg, Rebecca H; Wing, Rena R; Ryan, Donna H; Johnson, Karen C; Foreyt, John P; Hill, James O; Trence, Dace L; Vitolins, Mara Z

2009-04-01

This report provides a further analysis of the first year weight losses in the Look AHEAD (Action for Health in Diabetes) study and identifies factors associated with success. Participants were a total of 5,145 men and women with type 2 diabetes who were recruited at 16 sites and randomly assigned to an intensive lifestyle intervention (ILI) or a control condition, Diabetes Support and Education (DSE). During year 1, participants in ILI received comprehensive diet and physical activity counseling in a total of 42 group and individual sessions, compared with three educational sessions for DSE participants. As reported previously, at the end of the year, ILI participants lost 8.6% of initial weight, compared to 0.7% for DSE (P < 0.001). Within the ILI group, all racial/ethnic groups achieved clinically significant weight losses (>5.5%), although there were significant differences among groups. For the year, ILI participants attended an average of 35.4 treatment sessions and reported exercising a mean of 136.6 min/week and consuming a total of 360.9 meal replacement products. Greater self-reported physical activity was the strongest correlate of weight loss, followed by treatment attendance and consumption of meal replacements. The use of orlistat, during the second half of the year, increased weight loss only marginally in those ILI participants who had lost <5% of initial weight during the first 6 months and chose to take the medication thereafter as a toolbox option. The lifestyle intervention was clinically effective in all subsets of an ethnically and demographically diverse population.

The dependence of the action potential of the frog's heart on the external and intracellular sodium concentration

PubMed Central

Niedergerke, R.; Orkand, R. K.

1966-01-01

1. The overshoot of the action potential of the frog's heart was reduced when external sodium chloride was replaced by sucrose. However, the potential decrement was only 17·3 mV for a 10-fold reduction of sodium as compared with 58 mV expected on the basis of the sodium hypothesis of excitation. 2. Replacement of up to 75% of the external sodium by choline did not reduce the overshoot, provided atropine was present in sufficient concentrations to suppress any parasympathomimetic action. 3. The maximum rate of rise of the action potential markedly declined in low sodium fluids whether sucrose or choline chloride was used to replace sodium chloride. 4. The maximum rate of rise was reduced to only a small extent when external sodium was replaced by lithium. 5. Increasing the intracellular sodium concentration in exchange for lost potassium caused overshoots to decline. The effects resembled those obtained in similar experiments with skeletal muscle fibres (Desmedt, 1953). 6. Action potentials occurring under certain conditions even in the presence of very low external sodium concentrations (≤ 5% normal) also declined in height when the intracellular sodium concentration was increased. 7. The behaviour of the action potential in low external sodium concentrations may be explained by an action of calcium on the excitable membrane. PMID:5921833

Uncertainties in the measurements of water-soluble organic nitrogen in the aerosol

NASA Astrophysics Data System (ADS)

Matsumoto, Kiyoshi; Yamato, Koki

2016-11-01

In order to evaluate the positive and negative artifacts in the measurements of the water-soluble organic nitrogen (WSON) in the aerosols by filter sampling, comparative experiments between the filter sampling and denuder-filter sampling were conducted during both the warm and cold seasons. The results suggest that the traditional filter sampling underestimates the concentrations of the particulate WSON due to its volatilization loss, but this effect on the ratio of the WSON to the water-soluble total nitrogen (WSTN) was small probably because inorganic nitrogen species were also lost during the filter sampling. Approximately 32.5% of the WSON in the PM2.5 was estimated to be lost during the filter sampling. The denuder-filter sampling also demonstrated the existence of the WSON in the gas phase with approximately quarter concentrations of the WSON in the PM2.5. On the other hand, the filter sampling would overestimate the gaseous WSON concentration due to the loss of the WSON from the aerosol collection filter.

Slip slidin' away: A post-glacial environmental history of the Waipaoa River basin

NASA Astrophysics Data System (ADS)

Gomez, Basil; Rosser, Brenda J.

2018-04-01

The dramatic changes that occurred to the post-glacial landscape in the headwaters of the Waipaoa River basin are a consequence of perturbations about the equilibrium that exists between the rate of tectonic uplift and fluvial incision. At times when the amount of coarse sediment delivered to channels exceeds the capacity of streams to remove it, the channel bed rises at the rate of tectonic uplift. Once bedload overcapacity is replaced by undercapacity and the alluvial cover is depleted, streams reestablish contact with bedrock and recuperate the time lost to fluvial incision. The first major perturbation occurred during the final phase of the last glaciation (ca. 33-17.5 cal. ka), when aggradation was driven by a climate-forced variation in the relative supplies of sediment and water. We suggest that the subsequent transformation of channels in the headwaters of the Waipaoa River basin, from alluvial to bedrock, occurred as the atmospheric and oceanic circulation converged on their contemporary patterns ca. 12 cal. ka. A second major perturbation that continues to the present began ca. 1910-1912 CE, when a massive increase in sediment load was accompanied by a modest increase in water discharge after the native vegetation cover in the headwaters was replaced by pasture. The processes of terrace creation and incision are inherently unsteady, and in five interim cases incision was arrested by a transient increase in the thickness of the alluvial cover that was a response to climatic forcing. Events that disrupted the native vegetation cover in the headwaters also modulated patterns of sediment dispersal and accumulation in other parts of the fluvial system and caused rapid, storm-driven infilling of the Poverty Bay Flats. Tectonic subsidence dictates the course of the Waipaoa River across Poverty Bay Flats which, because the modern rate of floodplain construction by vertical accretion is rapid relative to the amount of destruction by lateral channel migration, has remained virtually unchanged for the past 100 years. During this time the channel assumed a narrower, deeper form that is in equilibrium with the contemporary supply of sediment and hydraulic regime.

Amniotic fluid stem cells: a promising therapeutic resource for cell-based regenerative therapy.

PubMed

Antonucci, Ivana; Pantalone, Andrea; Tete, Stefano; Salini, Vincenzo; Borlongan, Cesar V; Hess, David; Stuppia, Liborio

2012-01-01

Stem cells have been proposed as a powerful tool in the treatment of several human diseases, both for their ability to represent a source of new cells to replace those lost due to tissue injuries or degenerative diseases, and for the ability of produce trophic molecules able to minimize damage and promote recovery in the injured tissue. Different cell types, such as embryonic, fetal or adult stem cells, human fetal tissues and genetically engineered cell lines, have been tested for their ability to replace damaged cells and to restore the tissue function after transplantation. Amniotic fluid -derived Stem cells (AFS) are considered a novel resource for cell transplantation therapy, due to their high renewal capacity, the "in vitro" expression of embryonic cell lineage markers, and the ability to differentiate in tissues derived from all the three embryonic layers. Moreover, AFS do not produce teratomas when transplanted into animals and are characterized by a low antigenicity, which could represent an advantage for cell transplantation or cell replacement therapy. The present review focuses on the biological features of AFS, and on their potential use in the treatment of pathological conditions such as ischemic brain injury and bone damages.

Mesenchymal Stem Cells as a Source of Dopaminergic Neurons: A Potential Cell Based Therapy for Parkinson's Disease.

PubMed

Venkatesh, Katari; Sen, Dwaipayan

2017-01-01

Cell repair/replacing strategies for neurodegenerative diseases such as Parkinson's disease depend on well-characterized dopaminergic neuronal candidates that are healthy and show promising effect on the rejuvenation of degenerated area of the brain. Therefore, it is imperative to develop innovative therapeutic strategies that replace damaged neurons with new/functional dopaminergic neurons. Although several research groups have reported the generation of neural precursors/neurons from human/ mouse embryonic stem cells and mesenchymal stem cells, the latter is considered to be an attractive therapeutic candidate because of its high capacity for self-renewable, no adverse effect to allogeneic versus autologous transplants, high ethical acceptance and no teratoma formation. Therefore, mesenchymal stem cells can be considered as an ideal source for replacing lost cells in degenerative diseases like Parkinson's. Hence, the use of these cells in the differentiation of dopaminergic neurons becomes significant and thrives as a therapeutic approach to treat Parkinson's disease. Here we highlight the basic biology of mesenchymal stem cells, their differentiation potential into dopaminergic neurons and potential use in the clinics. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

A novel green tea meal replacement formula for weight loss among obese individuals: a randomized controlled clinical trial.

PubMed

Tsai, Ch-Huing; Chiu, Wan-Chen; Yang, Nae-Cherng; Ouyang, Chung-Mei; Yen, Yue-Horng

2009-01-01

To assess the efficacy and safety of a green tea meal replacement formula product for the treatment of obesity. A 12-week clinical trial was performed, in which 120 (25 male, 95 female) healthy, overweight and obese persons were included ( each of them occupy one-third of the whole population). The green tea formula was provided in the treatment group and normal diet was provided as control. More weight loss was found in the treatment group than the control (6.8 versus 2.3 kg; P <0.001). Also, the treatment group had a greater changes in total cholesterol (185.2 versus 215.2 mg/dl; P=0.011) and low-density lipoprotein cholesterol (106.7 versus 127.6 mg/dl; P<0.005). Among completers only, the treatment group again lost more weight (6.8 kg; n=54 versus 0.8 kg; n =56; P =0.001) and had a greater reduced total body fat mass (7.6%; n=37 versus 0.5%; P=0.005) This green tea meal replacement formula contributes to the lower body weight and reduced low-density lipoprotein cholesterol level.

Economic impact of providing workplace influenza vaccination. A model and case study application at a Brazilian pharma-chemical company.

PubMed

Burckel, E; Ashraf, T; de Sousa Filho, J P; Forleo Neto, E; Guarino, H; Yauti, C; Barreto F de, B; Champion, L

1999-11-01

To develop and apply a model to assess the economic value of a workplace influenza programme from the perspective of the employer. The model calculated the avoided costs of influenza, including treatment costs, lost productivity, lost worker added value and the cost of replacing workers. Subtracted from this benefit were the costs associated with a vaccination programme, including administrative costs, the time to give the vaccine, and lost productivity due to adverse reactions. The framework of the model can be applied to any company to estimate the cost-benefit of an influenza immunisation programme. The model developed was applied to 4030 workers in the core divisions of a Brazilian pharma-chemical company. The model determined a net benefit of $US121,441 [129,335 Brazilian reals ($Brz)], or $US35.45 ($Brz37.75) per vaccinated employee (1997 values). The cost-benefit ratio was 1:2.47. The calculations were subjected to a battery of 1-way and 2-way sensitivity analyses that determined that net benefit would be retained as long as the vaccine cost remained below $US45.40 ($Brz48.40) or the vaccine was at least 32.5% effective. Other alterations would retain a net benefit as well, including several combinations of incidence rate and vaccine effectiveness. The analysis suggests that providing an influenza vaccination programme can incur a substantial net benefit for an employer, although the size of the benefit will depend upon who normally absorbs the costs of treating influenza and compensating workers for lost work time due to illness, as well as the type of company in which the immunisation programme is applied.

40 CFR 141.84 - Lead service line replacement requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 24 2013-07-01 2013-07-01 false Lead service line replacement... PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Control of Lead and Copper § 141.84 Lead service line replacement requirements. (a) Systems that fail to meet the lead action level in tap samples...

40 CFR 141.84 - Lead service line replacement requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 24 2012-07-01 2012-07-01 false Lead service line replacement... PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Control of Lead and Copper § 141.84 Lead service line replacement requirements. (a) Systems that fail to meet the lead action level in tap samples...

40 CFR 141.84 - Lead service line replacement requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 23 2014-07-01 2014-07-01 false Lead service line replacement... PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Control of Lead and Copper § 141.84 Lead service line replacement requirements. (a) Systems that fail to meet the lead action level in tap samples...

Distribution and condition of larval and juvenile Lost River and shortnose suckers in the Williamson River Delta restoration project and Upper Klamath Lake, Oregon

USGS Publications Warehouse

Burdick, Summer M.

2012-01-01

Federally endangered Lost River sucker (Deltistes luxatus) and shortnose sucker (Chasmistes brevirostris) were once abundant throughout their range but populations have declined. They were extirpated from several lakes in the 1920s and may no longer reproduce in other lakes. Poor recruitment to the adult spawning populations is one of several reasons cited for the decline and lack of recovery of these species and may be the consequence of high mortality during juvenile life stages. High larval and juvenile sucker mortality may be exacerbated by an insufficient quantity of suitable or high-quality rearing habitat. In addition, larval suckers may be swept downstream from suitable rearing areas in Upper Klamath Lake into Keno Reservoir, where they are assumed lost to Upper Klamath Lake populations. The Nature Conservancy flooded about 3,600 acres (1,456 hectares) to the north of the Williamson River mouth (Tulana) in October 2007, and about 1,400 acres (567 hectares) to the south and east of the Williamson River mouth (Goose Bay Farms) in October 2008, in order to retain larval suckers in Upper Klamath Lake, create nursery habitat, and improve water quality. The U.S. Geological Survey joined a long-term research and monitoring program in collaboration with The Nature Conservancy, the Bureau of Reclamation, and Oregon State University in 2008 to assess the effects of the Williamson River Delta restoration on the early life-history stages of Lost River and shortnose suckers. The primary objectives of the research were to describe habitat colonization and use by larval and juvenile suckers and non-sucker fishes and to evaluate the effects of the restored habitat on the health and condition of juvenile suckers. This report summarizes data collected in 2010 by the U.S. Geological Survey as a part of this monitoring effort and follows two annual reports on data collected in 2008 and 2009. Restoration modifications made to the Williamson River Delta appeared to provide additional suitable rearing habitat for endangered Lost River and shortnose suckers from 2008 to 2010 based on sucker catches. Mean larval sample density was greater for both species in the Williamson River Delta than adjacent lake habitats in all 3 years. In addition to larval suckers, at least three age classes of juvenile suckers were captured in the delta. The shallow Goose Bay Farms and Tulana Emergent were among the most used habitats by age-0 suckers in 2009. Both of these environments became inaccessible due to low water in 2010, however, and were not sampled after July 19, 2010. In contrast, age-1 sucker catches shifted from the shallow water (about 0.5-1.5 m deep) on the eastern side of the Williamson River Delta in May, to deeper water environments (greater than 2 m) by the end of June or early July in all 3 years. Differential distribution among sucker species within the Williamson River Delta and between the delta and adjacent lakes indicated that shortnose suckers likely benefited more from the restored Williamson River Delta than Lost River or Klamath largescale suckers (Catostomus snyderi). Catch rates in shallow-water habitats within the delta were higher for shortnose and Klamath largescale sucker larvae than for larval Lost River suckers in 2008, 2009, and 2010. Shortnose suckers also comprised the greatest portion of age-0 suckers captured in the Williamson River Delta in all 3 years of the study. The relative abundance of age-1 shortnose suckers was high in our catches compared to age-1 Lost River suckers in 2009 and 2010. The restored delta also created habitat for several piscivorous fishes, but only two appeared to pose a meaningful threat of predation to suckers - fathead minnows (Pimephales promelas) and yellow perch (Perca flavescens). Fathead minnows that prey on larval but not juvenile suckers dominated catches in all sampling areas. Yellow perch also were abundant throughout the study area, but based on their gape size and co-occurrence with suckers, most were only capable of preying on larvae. Low May lake-surface elevation, below average snow pack, and anticipated irrigation demands indicated late summer water levels in Upper Klamath Lake would be unusually low in 2010. In response to concerns by the Fish and Wildlife Service and The Nature Conservancy that low-water conditions might strand fish on the delta, low water seine surveys were implemented. Eleven fishes, including both endangered suckers, were captured in seine surveys, including both species of suckers, which continued to use shallow water less than 0.4 m deep through September 21. Lake elevation declined to 1,261.54 m (4,138.9 feet) in mid-September 2010, but did not appear to strand fish or cause large-scale fish mortality.

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Science.gov Websites

gravel road. Four children drowned when they were swept down a swollen creek. Reports stated that up to when he lost control of the vehicle in the current causing the cab to fill with water. The passenger of in 12 feet of water in a ditch. Several people who tried to rescue the victim were taken to a local

Embolized stems recover overnight in Zea Mays: the role of soil water, root pressure, and nighttime transpiration

USDA-ARS?s Scientific Manuscript database

It is not currently well-understood how much xylem conductance is lost in maize plants during the day, if conductance is recovered during the night, or what soil water conditions are required for recovery to take place. To answer these questions we designed a greenhouse experiment whereby two genet...

Near-optimal response of instantaneous transpiration efficiency to vapour pressure deficit, temperature and [CO2] in cotton (Gossypium hirsutum L.).

USDA-ARS?s Scientific Manuscript database

The instantaneous transpiration efficiency (ITE, the ratio of photosynthesis rate to transpiration) is an important variable for crops, because it ultimately affects dry mass production per unit of plant water lost to the atmosphere. The theory that stomata optimize carbon uptake per unit water used...

Long-Term Monitoring of Rainfed Wheat Yield and Soil Water at the Loess Plateau Reveals Low Water Use Efficiency

PubMed Central

Qin, Wei; Chi, Baoliang; Oenema, Oene

2013-01-01

Increasing crop yield and water use efficiency (WUE) in dryland farming requires a quantitative understanding of relationships between crop yield and the water balance over many years. Here, we report on a long-term dryland monitoring site at the Loess Plateau, Shanxi, China, where winter wheat was grown for 30 consecutive years and soil water content (0–200 cm) was measured every 10 days. The monitoring data were used to calibrate the AquaCrop model and then to analyse the components of the water balance. There was a strong positive relationship between total available water and mean cereal yield. However, only one-third of the available water was actually used by the winter wheat for crop transpiration. The remaining two-thirds were lost by soil evaporation, of which 40 and 60% was lost during the growing and fallow seasons, respectively. Wheat yields ranged from 0.6 to 3.9 ton/ha and WUE from 0.3 to 0.9 kg/m3. Results of model experiments suggest that minimizing soil evaporation via straw mulch or plastic film covers could potentially double wheat yields and WUE. We conclude that the relatively low wheat yields and low WUE were mainly related to (i) limited rainfall, (ii) low soil water storage during fallow season due to large soil evaporation, and (iii) poor synchronisation of the wheat growing season to the rain season. The model experiments suggest significant potential for increased yields and WUE. PMID:24302987

Accurate mass replacement method for the sediment concentration measurement with a constant volume container

NASA Astrophysics Data System (ADS)

Ban, Yunyun; Chen, Tianqin; Yan, Jun; Lei, Tingwu

2017-04-01

The measurement of sediment concentration in water is of great importance in soil erosion research and soil and water loss monitoring systems. The traditional weighing method has long been the foundation of all the other measuring methods and instrument calibration. The development of a new method to replace the traditional oven-drying method is of interest in research and practice for the quick and efficient measurement of sediment concentration, especially field measurements. A new method is advanced in this study for accurately measuring the sediment concentration based on the accurate measurement of the mass of the sediment-water mixture in the confined constant volume container (CVC). A sediment-laden water sample is put into the CVC to determine its mass before the CVC is filled with water and weighed again for the total mass of the water and sediments in the container. The known volume of the CVC, the mass of sediment-laden water, and sediment particle density are used to calculate the mass of water, which is replaced by sediments, therefore sediment concentration of the sample is calculated. The influence of water temperature was corrected by measuring water density to determine the temperature of water before measurements were conducted. The CVC was used to eliminate the surface tension effect so as to obtain the accurate volume of water and sediment mixture. Experimental results showed that the method was capable of measuring the sediment concentration from 0.5 up to 1200 kg m-3. A good liner relationship existed between the designed and measured sediment concentrations with all the coefficients of determination greater than 0.999 and the averaged relative error less than 0.2%. All of these seem to indicate that the new method is capable of measuring a full range of sediment concentration above 0.5 kg m-3 to replace the traditional oven-drying method as a standard method for evaluating and calibrating other methods.

Hydration characteristics of zirconium oxide replaced Portland cement for use as a root-end filling material.

PubMed

Camilleri, J; Cutajar, A; Mallia, B

2011-08-01

Zirconium oxide can be added to dental materials rendering them sufficiently radiopaque. It can thus be used to replace the bismuth oxide in mineral trioxide aggregate (MTA). Replacement of Portland cement with 30% zirconium oxide mixed at a water/cement ratio of 0.3 resulted in a material with adequate physical properties. This study aimed at investigating the microstructure, pH and leaching in physiological solution of Portland cement replaced zirconium oxide at either water-powder or water-cement ratios of 0.3 for use as a root-end filling material. The hydration characteristics of the materials which exhibited optimal behavior were evaluated. Portland cement replaced by zirconium oxide in varying amounts ranging from 0 to 50% in increments of 10 was prepared and divided into two sets. One set was prepared at a constant water/cement ratio while the other set at a constant water/powder ratio of 0.3. Portland cement and MTA were used as controls. The materials were analyzed under the scanning electron microscope (SEM) and the hydration products were determined. X-ray energy dispersive analysis (EDX) was used to analyze the elemental composition of the hydration products. The pH and the amount of leachate in Hank's balanced salt solution (HBSS) were evaluated. A material that had optimal properties that satisfied set criteria and could replace MTA was selected. The microstructure of the prototype material and Portland cement used as a control was assessed after 30 days using SEM and atomic ratio diagrams of Al/Ca versus Si/Ca and S/Ca versus Al/Ca were plotted. The hydration products of Portland cement replaced with 30% zirconium oxide mixed at water/cement ratio of 0.3 were calcium silicate hydrate, calcium hydroxide and minimal amounts of ettringite and monosulphate. The calcium hydroxide leached in HBSS solution resulted in an increase in the pH value. The zirconium oxide acted as inert filler and exhibited no reaction with the hydration by-products of Portland cement. A prototype dental material composed of Portland cement replaced with 30% zirconium oxide as radiopacifier leached calcium ions on hydration which reacted with phosphates present in simulated tissue fluids. This resulted in bioactive cement that could prospectively be used as a root-end filling material. The zirconium oxide acted as inert filler and did not participate in the hydration reaction of the Portland cement. Copyright © 2011 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

Water Resources of the Ground-Water System in the Unconsolidated Deposits of the Colville River Watershed, Stevens County, Washington

USGS Publications Warehouse

Kahle, Sue C.; Longpre, Claire I.; Smith, Raymond R.; Sumioka, Steve S.; Watkins, Anni M.; Kresch, David L.

2003-01-01

A study of the water resources of the ground-water system in the unconsolidated deposits of the Colville River Watershed provided the Colville River Watershed Planning Team with an assessment of the hydrogeologic framework, preliminary determinations of how the shallow and deeper parts of the ground-water system interact with each other and the surface-water system, descriptions of water-quantity characteristics including water-use estimates and an estimated water budget for the watershed, and an assessment of further data needs. The 1,007-square-mile watershed, located in Stevens County in northeastern Washington, is closed to further surface-water appropriations throughout most of the basin during most seasons. The information provided by this study will assist local watershed planners in assessing the status of water resources within the Colville River Watershed (Water Resources Inventory Area 59). The hydrogeologic framework consists of glacial and alluvial deposits that overlie bedrock and are more than 700 feet thick in places. Twenty-six hydrogeologic sections were constructed, using a map of the surficial geology and drillers' logs for more than 350 wells. Seven hydrogeologic units were delineated: the Upper outwash aquifer, the Till confining unit, the Older outwash aquifer, the Colville Valley confining unit, the Lower aquifer, the Lower confining unit, and Bedrock. Synoptic stream discharge measurements made in September 2001 identified gaining and losing reaches over the unconsolidated valley deposits. During the September measurement period, the Colville River gained flow from the shallow ground-water system near its headwaters to the town of Valley and lost flow to the shallow ground-water system from Valley to Chewelah. Downstream from Chewelah, the river generally lost flow, but the amounts lost were small and within measurement error. Ground-water levels indicate that the Lower aquifer and the shallow ground-water system may act as fairly independent systems. The presence of flowing wells completed in the Lower aquifer indicates upward head gradients along much of the Colville Valley floor. Total surface- and ground-water withdrawals during 2001 were estimated to be 9,340 million gallons. Water use for 2001, as a percentage of the total, was 75.3 percent for irrigation, 16.3 percent for public supply, 6.5 percent for private wells, and about 1 percent each for industrial and livestock use. An approximate water budget for a typical year in the Colville River Watershed shows that 27 inches of precipitation are balanced by 4.2 inches of streamflow discharge from the basin, 0.3 inch of ground-water discharge from the basin, and 22.5 inches of evapotranspiration.

Seasonal and Perennial Changes in the Distribution of Water in the Sapwood of Conifers in a Sub-Frigid Zone1

PubMed Central

Utsumi, Yasuhiro; Sano, Yuzou; Funada, Ryo; Ohtani, Jun; Fujikawa, Seizo

2003-01-01

An analysis was made of progressive changes in patterns of cavitation in the sapwood of three species of conifer (Larix kaempferi, Abies sachalinensis, and Picea jezoensis) that were growing in a sub-frigid zone. In all three conifers, all tracheids of the newly forming outermost annual ring were filled with water or cytoplasm during the period from May to August. However, many tracheids in the transition zone from earlywood to latewood lost water in September, presumably through drought-induced cavitation. Cavitated tracheids tended to be continuously distributed in a tangential direction. Subsequently, some earlywood tracheids of the outermost annual ring lost water during the period from January to March. This was associated with freeze-thaw cycles. In the second and third annual rings from the cambium of all three conifers, the lumina of most tracheids in the transition zone from earlywood to latewood contained no water. In contrast, some latewood tracheids near the annual ring boundary and many earlywood tracheids retained water in their lumina. The third annual ring had more cavitated tracheids than the second annual ring. Our observations indicated that cavitation progressed gradually in the tracheids of the conifers and that they were never refilled once cavitation had occurred. The region involved in water transport in conifers did not include the entire sapwood and differed among annual rings. PMID:12692342

Performance of Kaolin Clay on the Concrete Pavement

NASA Astrophysics Data System (ADS)

Abdullah, M. E.; Jaya, R. P.; Shahafuddin, M. N. A.; Yaacob, H.; Ibrahim, M. H. Wan; Nazri, F. M.; Ramli, N. I.; Mohammed, A. A.

2018-05-01

This paper investigates the performance of concrete pavement containing kaolin clay with their engineering properties and to determine the optimum kaolin clay content. The concrete used throughout the study was designed as grade 30 MPa strength with constant water to cement ratio of 0.49. The compressive strength, flexural strength and water absorption test was conducted in this research. The concrete mix designed with kaolin clay as cement replacement comprises at 0%, 5%, 10% and 15% by the total weight of cement. The results indicate that the strength of pavement concrete decreases as the percentage of kaolin clay increases. It also shows that the water absorption increases with the percentage of cement replacement. However, 5% kaolin clay is found to be the optimum level to replace cement in a pavement concrete.

The Effect of Root Coating with Titanium on Prevention of Root Resorption in Avulsed Teeth: An Animal Study

PubMed Central

Heydari, Azar; Tahmasbi, Soodeh; Badiee, Mohammadreza; Izadi, SeyedSadra; Mashhadi Abbas, Fatemeh; Mokhtari, Sepideh

2016-01-01

Introduction: Tooth avulsion is a real dental emergency. If immediate replantation is not performed, the avulsed tooth may be lost due to inflammatory or replacement resorption. This animal study aimed to evaluate the bone response to the titanium coating of the root surface as an artificial barrier, and prevention of resorption of avulsed teeth. Methods and Materials: This experimental study was conducted on four male dogs. The dogs were randomly divided into two groups for assessment at two and eight weeks. Four teeth were extracted in each animal. The root surfaces of the test group were coated with a titanium layer using the Electron Beam Deposition system. After 24 h, replantation of the teeth was performed. Two animals were sacrificed after two weeks and the remaining dogs were killed after eight weeks. The presence of inflammation, inflammatory resorption, replacement resorption, periodontal regeneration, periapical granuloma and ankylosis were evaluated through histological analyses. Results: Inflammatory root resorption was not present in any tooth except one tooth in the coated group after eight weeks. Replacement resorption was noted just in three of the non-coated teeth after two weeks and two teeth after eight weeks. The McNemar's test revealed that the frequency of replacement resorption in the non-coated group was significantly higher than the coated group (P=0.031). Conclusion: Based on the results of this study, it seems that coating the root surfaces of avulsed teeth with titanium may control the replacement root resorption. PMID:27790261

Aquaporins in Spinal Cord Injury: The Janus Face of AQP4

PubMed Central

Nesic, Olivera; Guest, James D.; Zivadinovic, Dragoslava; Narayana, Ponnada A.; Herrera, Juan J.; Grill, Raymond J.; Mokkapati, Venkata U.L.; Gelman, Benjamin B.; Lee, Julieann

2010-01-01

Although malfunction of spinal cord water channels (aquaporins, AQP) likely contributes to severe disturbances in ion/water homeostasis after spinal cord injury (SCI), their roles are still poorly understood. Here we report and discuss the potential significance of changes in the AQP4 expression in human SCI that generates GFAP-labeled astrocytes devoid of AQP4, and GFAP-labeled astroglia that overexpress AQP4. We used a rat model of contusion SCI to study observed changes in human SCI. AQP4-negative astrocytes are likely generated during the process of SCI-induced replacement of lost astrocytes, but their origin and role in SCI remains to be investigated. We found that AQP4-overexpression is likely triggered by hypoxia. Our transcriptional profiling of injured rat cords suggests that elevated AQP4-mediated water influx accompanies increased uptake of chloride and potassium ions which represents a protective astrocytic reaction to hypoxia. However, unbalanced water intake also results in astrocytic swelling that can contribute to motor impairment, but likely only in milder injuries. In severe rat SCI, a low abundance of AQP4-overexpressing astrocytes was found during the motor recovery phase. Our results suggest that severe rat contusion SCI is a better model to analyze AQP4 functions after SCI. We found that AQP4 increases in the chronic post-injury phase are associated with the development of pain-like behavior in SCI rats, while possible mechanisms underlying pain development may involve astrocytic swelling-induced glutamate release. In contrast, the formation and size of fluid-filled cavities occurring later after SCI does not appear to be affected by the extent of increased AQP4 levels. Therefore, the effect of therapeutic interventions targeting AQP4 will depend not only on the time interval after SCI or animal models, but also on the balance between protective role of increased AQP4 in hypoxia and deleterious effects of ongoing astrocytic swelling. PMID:20109536

Arsenic removal from drinking water by a household sand filter in Vietnam--effect of filter usage practices on arsenic removal efficiency and microbiological water quality.

PubMed

Nitzsche, Katja Sonja; Lan, Vi Mai; Trang, Pham Thi Kim; Viet, Pham Hung; Berg, Michael; Voegelin, Andreas; Planer-Friedrich, Britta; Zahoransky, Jan; Müller, Stefanie-Katharina; Byrne, James Martin; Schröder, Christian; Behrens, Sebastian; Kappler, Andreas

2015-01-01

Household sand filters are applied to treat arsenic- and iron-containing anoxic groundwater that is used as drinking water in rural areas of North Vietnam. These filters immobilize poisonous arsenic (As) via co-oxidation with Fe(II) and sorption to or co-precipitation with the formed Fe(III) (oxyhydr)oxides. However, information is lacking regarding the effect of the frequency and duration of filter use as well as of filter sand replacement on the residual As concentrations in the filtered water and on the presence of potentially pathogenic bacteria in the filtered and stored water. We therefore scrutinized a household sand filter with respect to As removal efficiency and the presence of fecal indicator bacteria in treated water as a function of filter operation before and after sand replacement. Quantification of As in the filtered water showed that periods of intense daily use followed by periods of non-use and even sand replacement did not significantly (p<0.05) affect As removal efficiency. The As concentration was reduced during filtration from 115.1 ± 3.4 μg L(-1) in the groundwater to 5.3 ± 0.7 μg L(-1) in the filtered water (95% removal). The first flush of water from the filter contained As concentrations below the drinking water limit and suggests that this water can be used without risk for human health. Colony forming units (CFUs) of coliform bacteria increased during filtration and storage from 5 ± 4 per 100mL in the groundwater to 5.1 ± 1.5 × 10(3) and 15 ± 1.4 × 10(3) per 100mL in the filtered water and in the water from the storage tank, respectively. After filter sand replacement, CFUs of Escherichia coli of <100 per 100mL were quantified. None of the samples contained CFUs of Enterococcus spp. No critical enrichment of fecal indicator bacteria belonging to E. coli or Enterococcus spp. was observed in the treated drinking water by qPCR targeting the 23S rRNA gene. The results demonstrate the efficient and reliable performance of household sand filters regarding As removal, but indicate a potential risk for human health arising from the enrichment of coliform bacteria during filtration and from E. coli cells that are introduced by sand replacement. Copyright © 2014 Elsevier B.V. All rights reserved.

Why new neutron detector materials must replace helium-3

NASA Astrophysics Data System (ADS)

Hurd, Alan J.; Kouzes, Richard T.

2014-10-01

Helium-3 has such unique physical and nuclear properties that to a physicist it seems appalling the isotope was once indiscriminately released to the atmosphere as a waste gas. Not gravitationally bound to our planet, a He-3 atom is effectively lost to the human race once released. Consequently, when a confluence of independent factors in national security and research in the last decade created a "custody battle" over this scarce isotope, an intense search for substitutes and alternative technologies ensued for various applications. This Focus Point of EPJ Plus is dedicated to neutron detector alternatives.

Landscape features, standards, and semantics in U.S. national topographic mapping databases

USGS Publications Warehouse

Varanka, Dalia

2009-01-01

The objective of this paper is to examine the contrast between local, field-surveyed topographical representation and feature representation in digital, centralized databases and to clarify their ontological implications. The semantics of these two approaches are contrasted by examining the categorization of features by subject domains inherent to national topographic mapping. When comparing five USGS topographic mapping domain and feature lists, results indicate that multiple semantic meanings and ontology rules were applied to the initial digital database, but were lost as databases became more centralized at national scales, and common semantics were replaced by technological terms.

Initial prejudices create cross-generational intergroup mistrust

PubMed Central

Uhlmann, Eric Luis; Obloj, Tomasz

2018-01-01

The present investigation modeled the emergence and persistence of intergroup bias and discrimination in artificial societies. Initial unfair prejudices held by members of a dominant group elicit confirmatory behavior (diminished cooperation) from members of a subordinate group via a self-fulfilling prophecy. Further, when individual learning is tempered by conformity to peers, inaccurate beliefs about the stigmatized subordinate group persist long-term. Even completely replacing dominant group members with enlightened individuals through generational change is inadequate to break the cycle of intergroup distrust and non-collaboration. The longer the enlightenment of a society is delayed, the more intergroup trust is irretrievably lost. PMID:29694405

Field testing the Wildlink Capture Collar on wolves

USGS Publications Warehouse

Mech, L. David; Gesit, Eric L.

1992-01-01

Seventeen Wildlink capture collars were tested 61 times on 18 gray wolves (Canis lupus) during 1989-1991 in the Superior National Forest of northeastern Minnesota. Overall success rate was 89%, and most failures were attributable to premature battery expiration. When batteries were changed ≤ every 2 months, 17 of 17 tests succeeded. With an upgraded version of the collar in which batteries lasted longer, 17 of 18 tests succeeded. Over the 2-year study, 6 of the 17 collars were lost. For serially recapturing individuals, the Wildlink collar proved useful and reliable if care was taken to replace batteries at proper intervals.

Child spacing and child mortality among Nigerian Igbos.

PubMed

Ebigbo, P O; Chukudebelu, W O

1980-01-01

Until recently, a birth interval of at least two years was the norm in the Nigerian Igbo culture, a practice necessary for infant health and survival. A study of antenatal patients of the University of Nigeria Teaching Hospital, Enugu, Nigeria, shows that this cultural pattern has been disrupted by Westernization, urbanization and consumerism. The patients studied had an average of four pregnancies in five years. Roughly half of those conceived did not survive: 41% of the patients reported having lost at least one child. Modern family planning methods are urged as replacements for the abandoned traditional methods of child spacing.

Eight-year follow-up of autogenous tooth transplantation involving multidisciplinary treatment.

PubMed

Candeiro, George T M; Alencar-Júnior, Emmanuel A; Scarparo, Henrique C; Furtado-Júnior, João H C; Gavini, Giulio; Caldeira, Celso L

2015-09-01

Although autogenous tooth transplantation is a widely reported procedure, its success is dependent on a number of factors. Here we describe the surgical technique, endodontic treatment and rehabilitation employed for a patient in whom a lower right third molar was transplanted to substitute an adjacent second molar with extensive caries. During an 8-year follow-up period, normal periodontal healing was observed and no infection, ankylosis or progressive resorption occurred. It may be concluded that transplantation of a third molar is a practicable approach for replacement of a lost permanent tooth, with restoration of esthetics and function.

A room of one's own: the SRO and the single elderly.

PubMed

Crystal, S; Beck, P

1992-10-01

A survey of 485 single-room occupancy housing (SRO) residents in New York City found elderly residents strongly preferred to remain in centrally located neighborhoods where apartment housing was beyond their means; did not wish to share a housing unit; and had little confidence that they could find acceptable housing if they lost their present unit. For many elderly residents, SROs meet needs not easily met by available alternatives. Results suggest the need to maintain this housing option for older persons and replace losses that have accompanied gentrification in many central city areas.

A Clear Vision.

ERIC Educational Resources Information Center

Fawcett, Paul

2000-01-01

Explores the process of keeping pool water safe and healthful through careful planning of filter purchases and replacement. Deciding when filters need replacing, the type of filter required, and installation planning are discussed. (GR)

Replacing fallow with cover crops in a semiarid soil: effects on soil properties

USDA-ARS?s Scientific Manuscript database

Replacement of fallow in crop-fallow systems with cover crops (CCs) may improve soil properties. We assessed whether replacing fallow in no-till winter wheat (Triticum aestivum L.)-fallow with winter and spring CCs for five years reduced wind and water erosion, increased soil organic carbon (SOC), a...

Replacing fallow with cover crops in a semiarid soil:Effects on soil properties

USDA-ARS?s Scientific Manuscript database

Replacement of fallow in crop–fallow systems with cover crops (CCs) may improve soil properties. We assessed whether replacing fallow in no-till winter wheat (Triticum aestivum L.)–fallow with winter and spring CCs for 5 years reduced wind and water erosion, increased soil organic carbon (SOC), and ...

Colon Capsule Endoscopy for the Detection of Colorectal Polyps: An Economic Analysis

PubMed Central

Palimaka, Stefan; Blackhouse, Gord; Goeree, Ron

2015-01-01

Background Colorectal cancer is a leading cause of mortality and morbidity in Ontario. Most cases of colorectal cancer are preventable through early diagnosis and the removal of precancerous polyps. Colon capsule endoscopy is a non-invasive test for detecting colorectal polyps. Objectives The objectives of this analysis were to evaluate the cost-effectiveness and the impact on the Ontario health budget of implementing colon capsule endoscopy for detecting advanced colorectal polyps among adult patients who have been referred for computed tomographic (CT) colonography. Methods We performed an original cost-effectiveness analysis to assess the additional cost of CT colonography and colon capsule endoscopy resulting from misdiagnoses. We generated diagnostic accuracy data from a clinical evidence-based analysis (reported separately), and we developed a deterministic Markov model to estimate the additional long-term costs and life-years lost due to false-negative results. We then also performed a budget impact analysis using data from Ontario administrative sources. One-year costs were estimated for CT colonography and colon capsule endoscopy (replacing all CT colonography procedures, and replacing only those CT colonography procedures in patients with an incomplete colonoscopy within the previous year). We conducted this analysis from the payer perspective. Results Using the point estimates of diagnostic accuracy from the head-to-head study between colon capsule endoscopy and CT colonography, we found the additional cost of false-positive results for colon capsule endoscopy to be $0.41 per patient, while additional false-negatives for the CT colonography arm generated an added cost of $116 per patient, with 0.0096 life-years lost per patient due to cancer. This results in an additional cost of $26,750 per life-year gained for colon capsule endoscopy compared with CT colonography. The total 1-year cost to replace all CT colonography procedures with colon capsule endoscopy in Ontario is about $2.72 million; replacing only those CT colonography procedures in patients with an incomplete colonoscopy in the previous year would cost about $740,600 in the first year. Limitations The difference in accuracy between colon capsule endoscopy and CT colonography was not statistically significant for the detection of advanced adenomas (≥ 10 mm in diameter), according to the head-to-head clinical study from which the diagnostic accuracy was taken. This leads to uncertainty in the economic analysis, with results highly sensitive to changes in diagnostic accuracy. Conclusions The cost-effectiveness of colon capsule endoscopy for use in patients referred for CT colonography is $26,750 per life-year, assuming an increased sensitivity of colon capsule endoscopy. Replacement of CT colonography with colon capsule endoscopy is associated with moderate costs to the health care system. PMID:26366240

Swans replacing filter in U.S. Laboratory

NASA Image and Video Library

2014-07-15

ISS040-E-064628 (15 July 2014) --- NASA astronaut Steve Swanson, Expedition 40 commander, replaces filters in the Potable Water Dispenser (PWD) in the Destiny laboratory of the International Space Station.

Monitoring of water and nitrate leaching in an almond orchard

NASA Astrophysics Data System (ADS)

Kandelous, M. M.; Moradi, A. B.; Brown, P.; Hopmans, J. W.

2013-12-01

The quality of groundwater is specifically vulnerable in irrigated agricultural lands such as in California and many other (semi-) arid regions of the world. The regular application of nitrogen fertilizers with irrigation water is likely responsible for the increase in nitrate concentrations of groundwater resources such as in CA's main agricultural areas in the Salinas Valley and the Tulare Lake Basin. Since groundwater contamination regulations are going to be implemented, improved fertigation practices may become an essential part of CA farming operations. Therefore, we conducted a field study in an almond orchard located in Lost Hills, CA which provides critical information on the movement of water and nutrients through the soil under variable soil moisture conditions. Water balance and Darcy equation were two approaches used to estimate the leaching in this study. Given the amount of applied irrigation water using flowmeter, water lost through evapotranspiration measured by Eddy-Covariance tower, changes in soil water storage using neutron probe data, and precipitation data provided by a nearby CIMIS station, we applied water balance to estimate the amount of leaching water. In the other hand, coupled deep tensiometers were used to calculate the head gradient below the root zone, thereby estimating the leaching flux with Darcy equation for known hydraulic conductivity of layer between two tensiometers. Although, the cumulative amount of leaching estimated by water balance were in the same order of magnitude as what was estimated using Darcy method, the uncertainties and different cumulative trend observed in each method suggest further evaluation of collected data and also looking for an alternative method which could reduce the observed uncertainty.

Enhanced transpiration rate in the high pigment 1 tomato mutant and its physiological significance.

PubMed

Carvalho, R F; Aidar, S T; Azevedo, R A; Dodd, I C; Peres, L E P

2011-05-01

Tomato high pigment (hp) mutants represent an interesting horticultural resource due to their enhanced accumulation of carotenoids, flavonoids and vitamin C. Since hp mutants are known for their exaggerated light responses, the molecules accumulated are likely to be antioxidants, recruited to deal with light and others stresses. Further phenotypes displayed by hp mutations are reduced growth and an apparent disturbance in water loss. Here, we examined the impact of the hp1 mutation and its near isogenic line cv Micro-Tom (MT) on stomatal conductance (gs), transpiration (E), CO(2) assimilation (A) and water use efficiency (WUE). Detached hp1 leaves lost water more rapidly than control leaves, but this behaviour was reversed by exogenous abscisic acid (ABA), indicating the ability of hp1 to respond to this hormone. Although attached hp1 leaves had enhanced gs, E and A compared to control leaves, genotypic differences were lost when water was withheld. Both instantaneous leaf-level WUE and long-term whole plant WUE did not differ between hp1 and MT. Our results indicate a link between exaggerated light response and water loss in hp1, which has important implications for the use of this mutant in both basic and horticultural research. © 2011 German Botanical Society and The Royal Botanical Society of the Netherlands.

29 CFR 1910.422 - Procedures during dive.

Code of Federal Regulations, 2011 CFR

2011-07-01

... applicable to each diving operation unless otherwise specified. (b) Water entry and exit. (1) A means capable... from a dive team member; (3) Communications are lost and can not be quickly re-established between the...

29 CFR 1910.422 - Procedures during dive.

Code of Federal Regulations, 2012 CFR

2012-07-01

... applicable to each diving operation unless otherwise specified. (b) Water entry and exit. (1) A means capable... from a dive team member; (3) Communications are lost and can not be quickly re-established between the...

29 CFR 1910.422 - Procedures during dive.

Code of Federal Regulations, 2010 CFR

2010-07-01

... applicable to each diving operation unless otherwise specified. (b) Water entry and exit. (1) A means capable... from a dive team member; (3) Communications are lost and can not be quickly re-established between the...

29 CFR 1910.422 - Procedures during dive.

Code of Federal Regulations, 2014 CFR

2014-07-01

... applicable to each diving operation unless otherwise specified. (b) Water entry and exit. (1) A means capable... from a dive team member; (3) Communications are lost and can not be quickly re-established between the...

29 CFR 1910.422 - Procedures during dive.

Code of Federal Regulations, 2013 CFR

2013-07-01

... applicable to each diving operation unless otherwise specified. (b) Water entry and exit. (1) A means capable... from a dive team member; (3) Communications are lost and can not be quickly re-established between the...

40 CFR 796.3500 - Hydrolysis as a function of pH at 25 °C.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) TOXIC SUBSTANCES CONTROL ACT (CONTINUED) CHEMICAL FATE TESTING GUIDELINES Transformation Processes § 796...) in water in which the X group is lost. These reactions generally follow the same type of rate laws... elements of water (H2O). This type of transformation often results in the net exchange of a group X, on an...

Flocculation of wheat straw soda lignin by hemoglobin and chicken blood: Effects of cationic polymer or calcium chloride

USDA-ARS?s Scientific Manuscript database

Flocculation can be used to separate non-sulfonated lignin from base hydrolyzed biomass. In the industrial process, the lignin is isolated by filtration and washed with water. Some of the lignin is lost in the wash water, and flocculation can be used to recover this lignin. Several ways of enhanc...

Temperatures and Water Levels at Tanana Flats Monitoring Stations

DTIC Science & Technology

2008-04-01

a Druck pressure trans- ducer near the bottom. In response to this drawdown, the initial record showed a water level of 1.13 m on 1 April 2005, which...gradually increased to 1.68 m on 8 April. Freezing of the sensor on 9–10 April ended the reli- able water level record. A pair of replacement Drucks ...again, and a new Druck was installed to replace those that had been frozen. With rising tem- peratures at the bottom of the well, an injection of 400 g

Water Management Planning: A Case Study at Blue Grass Army Depot

DOE Office of Scientific and Technical Information (OSTI.GOV)

Solana, Amy E.; Mcmordie, Katherine

2006-04-03

Executive Order 13123, Greening the Government Through Efficient Energy Management, mandates an aggressive policy for reducing potable water consumption at federal facilities. Implementation guid¬ance from the U.S. Department of Energy (DOE) set a requirement for each federal agency to “reduce potable water usage by implementing life cycle, cost-effective water efficiency programs that include a water management plan, and not less than four Federal Energy Management Program (FEMP) Best Manage¬ment Practices (BMPs).” The objective of this plan is to gain full compliance with Executive Order 13123 and associated DOE implementation guidance on behalf of Blue Grass Army Depot (BGAD), Richmond, Kentucky.more » In accordance with this plan, BGAD must: • Incorporate the plan as a component of the Installation energy conservation plan • Investigate the water savings potential and life-cycle cost effectiveness of the Operations and Maintenance (O&M) and retrofit/replacement options associated with the ten FEMP BMPs • Put into practice all applicable O&M options • Identify retrofit/replacement options appropriate for implementation (based upon calculation of the simple payback periods) • Establish a schedule for implementation of applicable and cost-effective retrofit/replacement options.« less

The Feasibility of Palm Kernel Shell as a Replacement for Coarse Aggregate in Lightweight Concrete

NASA Astrophysics Data System (ADS)

Itam, Zarina; Beddu, Salmia; Liyana Mohd Kamal, Nur; Ashraful Alam, Md; Issa Ayash, Usama

2016-03-01

Implementing sustainable materials into the construction industry is fast becoming a trend nowadays. Palm Kernel Shell is a by-product of Malaysia’s palm oil industry, generating waste as much as 4 million tons per annum. As a means of producing a sustainable, environmental-friendly, and affordable alternative in the lightweight concrete industry, the exploration of the potential of Palm Kernel Shell to be used as an aggregate replacement was conducted which may give a positive impact to the Malaysian construction industry as well as worldwide concrete usage. This research investigates the feasibility of PKS as an aggregate replacement in lightweight concrete in terms of compressive strength, slump test, water absorption, and density. Results indicate that by using PKS for aggregate replacement, it increases the water absorption but decreases the concrete workability and strength. Results however, fall into the range acceptable for lightweight aggregates, hence it can be concluded that there is potential to use PKS as aggregate replacement for lightweight concrete.

Food, Feed and Fuel: a Story About Nitrogen

NASA Astrophysics Data System (ADS)

Galloway, J. N.; Burke, M. B.; Mooney, H. A.; Steinfeld, H.

2008-12-01

Humans obtain metabolic energy by eating food. Nitrogen is required to grow food, but natural supplies of N for human purposes have been inadequate since the beginning of the twentieth century. The Haber-Bosch process now provides a virtually inexhaustible supply of nitrogen, limited primarily by the cost of energy. However, most nitrogen used in food production is lost to the environment, where it cascades through environmental reservoirs contributing to many of the major environmental issues of the day. Furthermore, growing international trade in nitrogen-containing commodities is increasingly replacing wind and water as an important international transporter of nitrogen around the globe. Finally, the rapid growth in crop-based biofuels, and its attendant effects on the global production and trade of all agricultural commodities, could greatly affect global patterns of N use and loss. In the light of the findings above, this paper examines the role of nitrogen in food, feed and fuel production. It describes the beneficial consequences for food production and the negative consequences associated with the commodity nitrogen cascade and the environmental nitrogen cascade. The paper reviews estimates of future projections of nitrogen demands for food and fuel, including the impact of changing diets in the developing world. The paper concludes by presenting the potential interactions among global change, agricultural production and the nitrogen and carbon cycles.

Marine corrosion of mild steel at Lumut, Perak

NASA Astrophysics Data System (ADS)

Ting, Ong Shiou; Potty, Narayanan Sambu; Liew, Mohd. Shahir

2012-09-01

The corrosion rate of structural steels in the adverse marine and offshore environments affects the economic interest of offshore structures since the loss of steel may have significant impact on structural safety and performance. With more emphasis to maintain existing structures in service for longer time and hence to defer replacement costs, there is increasing interest in predicting corrosion rate at a given location for a given period of exposure once the protection coating or cathodic protection is lost. The immersion depth, salinity, steel composition and water pollution will be taken into account. Various corrosion allowances are prescribed for structural members by different standards. There are no studies to determine the appropriate corrosion allowance for steel structures in marine environment in Malaysia. The objectives of the research are to determine the nature and rate of corrosion in mm/year for steel structures in marine environment. It also tries to identify whether the corrosion rate is affected by differences in the chemical composition of the steels, and microalgae. Two sets of corrosion coupons of Type 3 Steel consisting of mild steel were fabricated and immersed in seawater using steel frames. The corrosion rate of the coupon in mm/ per year is estimated based on the material weight loss with time in service. The results are compared with recommendations of the code.

Superior underwater vision in a human population of sea gypsies.

PubMed

Gislén, Anna; Dacke, Marie; Kröger, Ronald H H; Abrahamsson, Maths; Nilsson, Dan-Eric; Warrant, Eric J

2003-05-13

Humans are poorly adapted for underwater vision. In air, the curved corneal surface accounts for two-thirds of the eye's refractive power, and this is lost when air is replaced by water. Despite this, some tribes of sea gypsies in Southeast Asia live off the sea, and the children collect food from the sea floor without the use of visual aids. This is a remarkable feat when one considers that the human eye is not focused underwater and small objects should remain unresolved. We have measured the visual acuity of children in a sea gypsy population, the Moken, and found that the children see much better underwater than one might expect. Their underwater acuity (6.06 cycles/degree) is more than twice as good as that of European children (2.95 cycles/degree). Our investigations show that the Moken children achieve their superior underwater vision by maximally constricting the pupil (1.96 mm compared to 2.50 mm in European children) and by accommodating to the known limit of human performance (15-16 D). This extreme reaction-which is routine in Moken children-is completely absent in European children. Because they are completely dependent on the sea, the Moken are very likely to derive great benefit from this strategy.

Hydration: special issues for playing football in warm and hot environments.

PubMed

Shirreffs, S M

2010-10-01

The high metabolic rates and body temperatures sustained by football players during training and matches causes sweating--particularly when in warm or hot environments. There is limited published data on the effects of this sweat loss on football performance. The limited information available, together with knowledge of the effects of sweat loss in other sports with skill components as well as endurance and sprint components, suggests that the effects of sweating will be similar as in these other activities. Therefore, the generalization that, on average, a body mass reduction equivalent to 2% should be the acceptable limit of sweat losses seems reasonable. This magnitude and more, of sweat loss is a common occurrence for some players. Sodium is the main electrolyte lost in sweat but there is large variability in sodium losses between players. However, the extent of sodium losses in some players may be such that its replacement is warranted for these players. Although football is a team sport, the great individual variability in sweat and electrolyte losses of players in the same training session or match dictates that individual monitoring to determine individual water and electrolyte requirements should be an essential part of a player's nutrition strategy. © 2010 John Wiley & Sons A/S.

Replacing positivism in medical geography.

PubMed

Bennett, David

2005-06-01

Revisiting debates about philosophical approaches in medical geography suggests that logical positivism may have been prematurely discarded. An analysis of authoritative texts in medical geography and their sources in human geography shows that logical positivism has been conflated with Comtean positivism, science, empiricism, quantification, science politics, scientism and so on, to produce the "standard version" of the all-purpose pejorative "positivism", which it is easy to dismiss as an evil. It is argued that the standard version fails to do justice to logical positivism, being constructed on sources which are at some distance from the logical positivist movement itself. An alternative approach is then developed, an historically and geographically situated interpretation of logical positivism as a deliberately and knowingly constructed oppositional epistemology within an oppressive and anti-scientific culture predicated on idealist intuitionism. Contrasting the standard version with this alternative reading of logical positivism suggests that much may have been lost in human, and thus, medical geography, by throwing out the logical positivist baby with the "positivism" bath water. It is concluded that continuing to unpack the standard version of logical positivism may identify benefits from a more nuanced appreciation of logical positivism, but it is premature to take these to the level of detailed impacts on the kinds of medical geographies that could be done or the ways of doing them.

The Potential Transformation of Our Species by Neural Enhancement

PubMed Central

Zehr, E. Paul

2015-01-01

ABSTRACT. Neural enhancement represents recovery of function that has been lost due to injury or disease pathology. Restoration of functional ability is the objective. For example, a neuroprosthetic to replace a forearm and hand lost to the ravages of war or industrial accident. However, the same basic constructs used for neural enhancement after injury could amplify abilities that are already in the natural normal range. That is, neural enhancement technologies to restore function and improve daily abilities for independent living could be used to improve so-called normal function to ultimate function. Approaching that functional level by use and integration of technology takes us toward the concept of a new species. This new subspecies—homo sapiens technologicus—is one that uses technology not just to assist but to change its own inherent biological function. The author uses examples from prosthetics and neuroprosthetics to address the issue of the limitations of constructs on the accepted range of human performance ability and aims to provide a cautionary view toward reflection on where our science may take the entire species. PMID:25575224

The springs of Lake Pátzcuaro: chemistry, salt-balance, and implications for the water balance of the lake

USGS Publications Warehouse

Bischoff, James L.; Israde-Alcántara, Isabel; Garduno-Monroy, Victor H.; Shanks, Wayne C.

2004-01-01

Lake Pa??tzcuaro, the center of the ancient Tarascan civilization located in the Mexican altiplano west of the city of Morelia, has neither river input nor outflow. The relatively constant lake-salinity over the past centuries indicates the lake is in chemical steady state. Springs of the south shore constitute the primary visible input to the lake, so influx and discharge must be via sub-lacustrine ground water. The authors report on the chemistry and stable isotope composition of the springs, deeming them representative of ground-water input. The springs are dominated by Ca, Mg and Na, whereas the lake is dominated by Na. Combining these results with previously published precipitation/rainfall measurements on the lake, the authors calculate the chemical evolution from spring water to lake water, and also calculate a salt balance of the ground-water-lake system. Comparing Cl and ??18O compositions in the springs and lake water indicates that 75-80% of the spring water is lost evaporatively during evolution toward lake composition. During evaporation Ca and Mg are lost from the water by carbonate precipitation. Each liter of spring water discharging into the lake precipitates about 18.7 mg of CaCO3. Salt balance calculations indicate that ground water input to the lake is 85.9??106 m3/a and ground water discharge from the lake is 23.0??106 m3/a. Thus, the discharge is about 27% of the input, with the rest balanced by evaporation. A calculation of time to reach steady-state ab initio indicates that the Cl concentration of the present day lake would be reached in about 150 a. ?? 2004 Elsevier Ltd. All rights reserved.

The study of Lake Urmia desiccation: morphometry impress

NASA Astrophysics Data System (ADS)

Moradi, Ayoub; Rasouli, Ali Akbar; Roostaei, Shahram

2017-04-01

Located in northwestern Iran, the hypersaline Lake Urmia has started a serious uninterrupted desiccation since 1995. The lake has lost about eight meters of water level and about 75% of water surface area during past 20 years. In particular, the lake water volume decrement has been accelerated in recent years. The importance of the Lake Urmia for human life in northwestern Iran, and its destructive effects on a vast region if totally dry up, demands comprehensive studies of the lake level fluctuations mechanism. According to literature review, the water volume of the lake behaves sometimes differently from the water storage of the whole basin. Our time series analysis using Land Data Assimilation Systems also confirms those differences within last decades. In other hand, many studies addressed the lake desiccation to climatic changes and/or anthropogenic influences such as excessive dam constructions in the watershed during last decades. As water leaves the lake only through evaporation, the fluctuation of evaporation has a distinctive role in the lake level variations. Dramatic decreament in the lake extent indicates of a special morphometry. The lake's morphometry has made it vulnerable to temperature and salinity changes. It strongly controls the lake's water heat capacity and water density. And, it therefore controls the rate of evaporation from water surface. We study the role of lake's morphometry on the lake desiccation. Although, the global climatic change is known as the primary reason for current droughts in the Middle East generally, our preliminary results show that the lake's morphometry is the main cause for the accelerating of water volume lost in Lake Urmia. In particular, after 2007, lake's water temperature and density show significant variations. Water heat capacity and evaporation rate are consistent with information of lake's hypsometry.

[Osteoconductive behaviour of beta-tricalcium phosphate ceramics in osteoporotic, metaphyseal bone defects of the distal radius].

PubMed

Hainich, J; von Rechenberg, B; Jakubietz, R G; Jakubietz, M G; Giovanoli, P; Grünert, J G

2014-02-01

Surgical treatment of osteoporotic distal radius fractures with locking plates does not completely prevent loss of reduction. Additional bone deficit stabilisation with the use of bone substitute materials is receiving increased attention. Most knowledge on the in vivo behavior of bone substitutes originates from a small number of animal models after its implantation in young, good vascularized bone. This paper investigates the osteoconductivity, resorption and biocompatibility of beta-tricalcium phosphate as a temporary bone replacement in osteoporotic type distal radius fractures. 15 bone samples taken from the augmented area of the distal radius of elderly people during metal removal were examined. The material was found to be osteoconductive, good degradable, and biocompatible. Degrading process and remodelling to woven bone seem to require more time than in available comparative bioassays. The material is suitable for temporary replacement of lost, distal radius bone from the histological point of view. © Georg Thieme Verlag KG Stuttgart · New York.

Relations of hedonic hunger and behavioral change to weight loss among adults in a behavioral weight loss program utilizing meal-replacement products.

PubMed

Theim, Kelly R; Brown, Joshua D; Juarascio, Adrienne S; Malcolm, Robert R; O'Neil, Patrick M

2013-11-01

Greater self-regulatory behavior usage is associated with greater weight loss within behavioral weight loss treatments. Hedonic hunger (i.e., susceptibility to environmental food cues) may impede successful behavior change and weight loss. Adult men and women (N = 111, body mass index M ± SD = 35.89 ± 6.97 kg/m(2)) were assessed before and after a 15-week lifestyle change weight loss program with a partial meal-replacement diet. From pre- to post-treatment, reported weight control behavior usage improved and hedonic hunger decreased, and these changes were inversely related. Individuals with higher hedonic hunger scores at baseline showed the greatest weight loss. Similarly, participants with lower baseline use of weight control behaviors lost more weight, and increased weight control behavior usage was associated with greater weight loss-particularly among individuals with low baseline hedonic hunger. Further study is warranted regarding the significance of hedonic hunger in weight loss treatments.

Continuous tooth generation in mouse is induced by activated epithelial Wnt/β-catenin signaling

PubMed Central

Järvinen, Elina; Salazar-Ciudad, Isaac; Birchmeier, Walter; Taketo, Makoto M.; Jernvall, Jukka; Thesleff, Irma

2006-01-01

The single replacement from milk teeth to permanent teeth makes mammalian teeth different from teeth of most nonmammalian vertebrates and other epithelial organs such as hair and feathers, whose continuous replacement has been linked to Wnt signaling. Here we show that mouse tooth buds expressing stabilized β-catenin in epithelium give rise to dozens of teeth. The molar crowns, however, are typically simplified unicusped cones. We demonstrate that the supernumerary teeth develop by a renewal process where new signaling centers, the enamel knots, bud off from the existing dental epithelium. The basic aspects of the unlocked tooth renewal can be reproduced with a computer model on tooth development by increasing the intrinsic level of activator production, supporting the role of β-catenin pathway as an upstream activator of enamel knot formation. These results may implicate Wnt signaling in tooth renewal, a capacity that was all but lost when mammals evolved progressively more complicated tooth shapes. PMID:17121988

Deep patch technique for landslide repair. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Helwany, B.M.

1994-10-01

The report describes the laboratory testing of the `USFS deep patch` technique and a CTI modification of this technique for repairing landslides with geosynthetic reinforcement. The technique involves replacing sections of roadway lost due to landslides on top of a geosynthetically-reinforced embankment. The CTI modification involves replacing the reinforced slope with a geosynthetically-reinforced retaining wall with a truncated base. Both techniques rely on the cantilevering ability of the reinforced mass to limit the load on the foundation with a high slide potential. The tests with road base showed that (1) both the USFS and CTI repair reduced effectively the adversemore » effects of local landsliding on the highway pavement by preventing crack propagation; (2) the USFS repair increased the stability of the repaired slope, which was in progressive failure, by reducing the stresses exerted on it; and (3) the CTI repair produced substantially greater stresses on its foundation due to the truncated base of the reinforced mass.« less

Wound-Induced Polyploidization: Regulation by Hippo and JNK Signaling and Conservation in Mammals

PubMed Central

Losick, Vicki P.; Jun, Albert S.; Spradling, Allan C.

2016-01-01

Tissue integrity and homeostasis often rely on the proliferation of stem cells or differentiated cells to replace lost, aged, or damaged cells. Recently, we described an alternative source of cell replacement- the expansion of resident, non-dividing diploid cells by wound-induced polyploidization (WIP). Here we show that the magnitude of WIP is proportional to the extent of cell loss using a new semi-automated assay with single cell resolution. Hippo and JNK signaling regulate WIP; unexpectedly however, JNK signaling through AP-1 limits rather than stimulates the level of Yki activation and polyploidization in the Drosophila epidermis. We found that polyploidization also quantitatively compensates for cell loss in a mammalian tissue, mouse corneal endothelium, where increased cell death occurs with age in a mouse model of Fuchs Endothelial Corneal Dystrophy (FECD). Our results suggest that WIP is an evolutionarily conserved homeostatic mechanism that maintains the size and synthetic capacity of adult tissues. PMID:26958853

Professional and lay people perceptions of anterior maxillary esthetics

NASA Astrophysics Data System (ADS)

Roslan, Husniyati; Lillywhite, Graeme

2016-12-01

Achieving esthetic outcomes with implant-based restorations in the esthetic zone is a challenge due to the difficulty in replacing lost papillae. This study aimed to assess the influence of contact point position on the overall perception of esthetics as assessed by dental professionals and lay people. A cross-sectional study using self-administered questionnaire was distributed among 300 prosthodontists, general dentists and lay people in the United Kingdom. The questionnaire consisted of photographic images of a smile, intentionally altered using image manipulation software. Variations in contact length between maxillary central incisors were created to mimic the clinical situation when missing teeth were replaced with implant-supported crowns. These images were rated using VAS. One-way and two-way ANOVAs, and Tukey's test were used to analyze the data. The overall response rate by the three groups was 72%. Lay people and general dentists were more critical than prosthodontists in all VAS ratings (p < 0.000). Overall, all the groups perceived that the esthetic value reduced as the contact point increased in its length.

Rapid Lymphocyte Reconstitution of Unconditioned Immunodeficient Mice with Non-Self-Renewing Multipotent Hematopoietic Progenitors

PubMed Central

Bhattacharya, Deepta; Bryder, David; Rossi, Derrick J.; Weissman, Irving L.

2015-01-01

The replacement of abnormal hematopoietic stem cells (HSCs) with normal transplanted HSCs can correct a wide range of hematologic disorders. Here, we provide evidence that transplantation of more differentiated progenitor cells can be used to more rapidly correct lymphoid deficiencies in unconditioned immunocompromised mice. Transplantation of flk2+ multipotent progenitors led to robust B and T cell reconstitution that was maintained for at least 16 weeks. Antigenic challenge at 16 weeks post-transplantation revealed that reconstituted lymphocytes maintained a functional repertoire. In contrast to the persistent lymphocytic engraftment, myeloid chimerism was lost by 12 weeks post-transplantation consistent with the fact that flk2+ progenitors are non-self-renewing. Thus, while more differentiated progenitors are capable of rescuing lymphoid deficiencies, transplantation of HSCs must be used for the correction of non-lymphoid disorders, and, we propose, very long-term immune reconstitution. Based on recent evidence, we discuss novel strategies to achieve the replacement of abnormal HSCs without the use of cytotoxic conditioning regimens. PMID:16760650

Generation of functional organs from stem cells.

PubMed

Liu, Yunying; Yang, Ru; He, Zuping; Gao, Wei-Qiang

2013-01-01

We are now well entering the exciting era of stem cells. Potential stem cell therapy holds great promise for the treatment of many diseases such as stroke, traumatic brain injury, Alzheimer's disease, Parkinson's disease, amyotrophic lateral-sclerosis, myocardial infarction, muscular dystrophy, diabetes, and etc. It is generally believed that transplantation of specific stem cells into the injured tissue to replace the lost cells is an effective way to repair the tissue. In fact, organ transplantation has been successfully practiced in clinics for liver or kidney failure. However, the severe shortage of donor organs has been a major obstacle for the expansion of organ transplantation programs. Toward that direction, generation of transplantable organs using stem cells is a desirable approach for organ replacement and would be of great interest for both basic and clinical scientists. Here we review recent progress in the field of organ generation using various methods including single adult tissue stem cells, a blastocyst complementation system, tissue decellularization/recellularization and a combination of stem cells and tissue engineering.

Unraveling protein stabilization mechanisms: vitrification and water replacement in a glass transition temperature controlled system.

PubMed

Grasmeijer, N; Stankovic, M; de Waard, H; Frijlink, H W; Hinrichs, W L J

2013-04-01

The aim of this study was to elucidate the role of the two main mechanisms used to explain the stabilization of proteins by sugar glasses during drying and subsequent storage: the vitrification and the water replacement theory. Although in literature protein stability is often attributed to either vitrification or water replacement, both mechanisms could play a role and they should be considered simultaneously. A model protein, alkaline phosphatase, was incorporated in either inulin or trehalose by spray drying. To study the storage stability at different glass transition temperatures, a buffer which acts as a plasticizer, ammediol, was incorporated in the sugar glasses. At low glass transition temperatures (<50°C), the enzymatic activity of the protein strongly decreased during storage at 60°C. Protein stability increased when the glass transition temperature was raised considerably above the storage temperature. This increased stability could be attributed to vitrification. A further increase of the glass transition temperature did not further improve stability. In conclusion, vitrification plays a dominant role in stabilization at glass transition temperatures up to 10 to 20°C above storage temperature, depending on whether trehalose or inulin is used. On the other hand, the water replacement mechanism predominantly determines stability at higher glass transition temperatures. Copyright © 2013 Elsevier B.V. All rights reserved.

Estimated effects on water quality of Lake Houston from interbasin transfer of water from the Trinity River, Texas

USGS Publications Warehouse

Liscum, Fred; East, Jeffery W.

2000-01-01

The City of Houston is considering the transfer of water from the Trinity River to Lake Houston (on the San Jacinto River) to alleviate concerns about adequate water supplies for future water demands. The U.S. Geological Survey, in cooperation with the City of Houston, conducted a study to estimate the effects on the water quality of Lake Houston from the transfer of Trinity River water. A water-quality model, CE–QUAL–W2, was used to simulate six water-quality properties and constituents for scenarios of interbasin transfer of Trinity River water. Three scenarios involved the transferred Trinity River water augmenting streamflow in the East Fork of Lake Houston, and three scenarios involved the transferred water replacing streamflow from the West Fork of the San Jacinto River.The estimated effects on Lake Houston were determined by comparing volume-weighted daily mean water temperature, phosphorus, ammonia nitrogen, nitrite plus nitrate nitrogen, algal biomass, and dissolved oxygen simulated for each of the transfer scenarios to simulations for a base dataset. The effects of the interbasin transfer on Lake Houston do not appear to be detrimental to water temperature, ammonia nitrogen, or dissolved oxygen. Phosphorus and nitrite plus nitrate nitrogen showed fairly large changes when Trinity River water was transferred to replace West Fork San Jacinto River streamflow. Algal biomass showed large decreases when Trinity River water was transferred to augment East Fork Lake Houston streamflow and large increases when Trinity River water was transferred to replace West Fork San Jacinto River streamflow. Regardless of the scenario simulated, the model indicated that light was the limiting factor for algal biomass growth.

Variation in the carbon and oxygen isotope composition of plant biomass and its relationship to water-use efficiency at the leaf- and ecosystem-scales in a northern Great Plains grassland.

PubMed

Flanagan, Lawrence B; Farquhar, Graham D

2014-02-01

Measurements of the carbon (δ(13) Cm ) and oxygen (δ(18) Om ) isotope composition of C3 plant tissue provide important insights into controls on water-use efficiency. We investigated the causes of seasonal and inter-annual variability in water-use efficiency in a grassland near Lethbridge, Canada using stable isotope (leaf-scale) and eddy covariance measurements (ecosystem-scale). The positive relationship between δ(13) Cm and δ(18) Om values for samples collected during 1998-2001 indicated that variation in stomatal conductance and water stress-induced changes in the degree of stomatal limitation of net photosynthesis were the major controls on variation in δ(13) Cm and biomass production during this time. By comparison, the lack of a significant relationship between δ(13) Cm and δ(18) Om values during 2002, 2003 and 2006 demonstrated that water stress was not a significant limitation on photosynthesis and biomass production in these years. Water-use efficiency was higher in 2000 than 1999, consistent with expectations because of greater stomatal limitation of photosynthesis and lower leaf ci /ca during the drier conditions of 2000. Calculated values of leaf-scale water-use efficiency were 2-3 times higher than ecosystem-scale water-use efficiency, a difference that was likely due to carbon lost in root respiration and water lost during soil evaporation that was not accounted for by the stable isotope measurements. © 2013 John Wiley & Sons Ltd.

Cell-based therapeutic strategies for replacement and preservation in retinal degenerative diseases

PubMed Central

Jones, Melissa K.; Lu, Bin; Girman, Sergey; Wang, Shaomei

2017-01-01

Cell-based therapeutics offer diverse options for treating retinal degenerative diseases, such as age-related macular degeneration (AMD) and retinitis pigmentosa (RP). AMD is characterized by both genetic and environmental risks factors, whereas RP is mainly a monogenic disorder. Though treatments exist for some patients with neovascular AMD, a majority of retinal degenerative patients have no effective therapeutics, thus indicating a need for universal therapies to target diverse patient populations. Two main cell-based mechanistic approaches are being tested in clinical trials. Replacement therapies utilize cell-derived retinal pigment epithelial (RPE) cells to supplant lost or defective host RPE cells. These cells are similar in morphology and function to native RPE cells and can potentially supplant the responsibilities of RPE in vivo. Preservation therapies utilize supportive cells to aid in visual function and photoreceptor preservation partially by neurotrophic mechanisms. The goal of preservation strategies is to halt or slow the progression of disease and maintain remaining visual function. A number of clinical trials are testing the safety of replacement and preservation cell therapies in patients; however, measures of efficacy will need to be further evaluated. In addition, a number of prevailing concerns with regards to the immune-related response, longevity, and functionality of the grafted cells will need to be addressed in future trials. This review will summarize the current status of cell-based preclinical and clinical studies with a focus on replacement and preservation strategies and the obstacles that remain regarding these types of treatments. PMID:28111323

Ammonia Adsorption and Co-adsorption with Water in HKUST-1: Spectroscopic Evidence for Cooperative Interactions

DOE PAGES

Nijem, Nour; Fürsich, Katrin; Bluhm, Hendrik; ...

2015-10-09

Ammonia interactions and competition with water at the interface of nanoporous metal organic framework thin films of HKUST-1 (Cu 3Btc 2 , Btc = 1,3,5-benzenedicarboxylate) are investigated with ambient pressure X-ray photoelectron spectroscopy (APXPS). In the absence of water, ammonia adsorption at the Cu 2+ metal center weakens the metal-linker bond of the framework. In the presence of water, due to the higher binding energy (adsorption strength) of ammonia compared to water, ammonia replaces water at the unsaturated Cu 2+ metal centers. The water molecules remaining in the pores are stabilized by hydrogen bonding to ammonia. Hydrogen bonding between themore » water and ammonia strengthens the metal-ammonia interaction due to cooperative interactions. Cooperative interactions result in a reduction in the metal center oxidation state facilitating linker replacement by other species explaining the previously reported structure degradation.« less

Ammonia Adsorption and Co-adsorption with Water in HKUST-1: Spectroscopic Evidence for Cooperative Interactions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nijem, Nour; Fürsich, Katrin; Bluhm, Hendrik

Ammonia interactions and competition with water at the interface of nanoporous metal organic framework thin films of HKUST-1 (Cu 3Btc 2 , Btc = 1,3,5-benzenedicarboxylate) are investigated with ambient pressure X-ray photoelectron spectroscopy (APXPS). In the absence of water, ammonia adsorption at the Cu 2+ metal center weakens the metal-linker bond of the framework. In the presence of water, due to the higher binding energy (adsorption strength) of ammonia compared to water, ammonia replaces water at the unsaturated Cu 2+ metal centers. The water molecules remaining in the pores are stabilized by hydrogen bonding to ammonia. Hydrogen bonding between themore » water and ammonia strengthens the metal-ammonia interaction due to cooperative interactions. Cooperative interactions result in a reduction in the metal center oxidation state facilitating linker replacement by other species explaining the previously reported structure degradation.« less

Population Dynamics of Adult Lost River (Deltistes luxatus) and Shortnose (Chasmistes brevirostris) Suckers in Clear Lake Reservoir, California, 2006-08

USGS Publications Warehouse

Barry, Patrick M.; Janney, Eric C.; Hewitt, David A.; Hayes, Brian S.; Scott, Alta C.

2009-01-01

We report results from ongoing research into the population dynamics of endangered Lost River and shortnose suckers in Clear Lake Reservoir, California. Results are included for sampling that occurred from fall 2006 to spring 2008. We summarize catches and passive integrated transponder tagging efforts from trammel net sampling in fall 2006 and fall 2007, and report on detections of tagged suckers on remote antennas in the primary spawning tributary, Willow Creek, in spring 2007 and spring 2008. Results from trammel net sampling were similar to previous years, although catches of suckers in fall 2006 were lower than in 2007 and past years. Lost River and shortnose suckers combined made up about 80 percent of the sucker catch in each year, and more than 2,000 new fish were tagged across the 2 years. Only a small number of the suckers captured in fall sampling were recaptures of previously tagged fish, reinforcing the importance of remote detections of fish for capture-recapture analysis. Detections of tagged suckers in Willow Creek were low in spring 2007, presumably because of low flows. Nonetheless, the proportions of tagged fish that were detected were reasonably high and capture-recapture analyses should be possible after another year of data collection. Run timing for Lost River and shortnose suckers was well described by first detections of individuals by antennas in Willow Creek, although we may not have installed the antennas early enough in 2008 to monitor the earliest portion of the Lost River sucker migration. The duration and magnitude of the spawning runs for both species were influenced by flows and water temperature. Flows in Willow Creek were much higher in 2008 than in 2007, and far more detections were recorded in 2008 and the migrations were more protracted. In both years and for both species, migrations began in early March at water temperatures between 5 and 6 deg C and peaks were related to periods of increasing water temperature. The sex ratio of Lost River suckers detected in Willow Creek was skewed toward males, despite consistently more females having been tagged in fall sampling. This pattern indicates that some tagged female Lost River suckers may be spawning elsewhere in the system, and we intend to investigate this possibility to verify or alter the representativeness of our spring monitoring. Length frequency analysis of fall trammel net catches showed that the populations of both species in Clear Lake Reservoir have undergone major demographic transitions during the last 15 years. In the mid-1990s, the populations were dominated by larger fish and showed little evidence of recent recruitment. These larger fish apparently disappeared in the late 1990s and early 2000s, and the populations are now dominated by fish that recruited into the adult populations in the late 1990s. The length frequencies from the last 4 years provide evidence of consistent recruitment into the Lost River sucker population, but provide no such evidence for the shortnose sucker population. Overall, annual growth rates for both species in Clear Lake were 2-4 times greater than growth rates for conspecifics in Upper Klamath Lake. However, little or no growth occurred for either species in Clear Lake between 2006 and 2007. Based on available evidence, we are unable to fully explain differences in growth rates between systems or among years within Clear Lake.

Nasal Wash Treatment

MedlinePlus

... Guidelines Wash your hands. Make the nasal wash solution. Do not use tap water for the nasal ... Whichever water you use to make the saline solution, replace container or water at least weekly. To ...

The hydrogeology of urbanization: The lost springs of Washington, D.C., late Tertiary and Quaternary sediments of D.C., and the Baltimore Long Term Ecological Research site (LTER): Chapter

USGS Publications Warehouse

Bhaskar, Aditi; Pavich, Milan J.; Sharp, John M.

2015-01-01

Urbanization is a major process now shaping the environment. This field trip looks at the hydrogeology of the general Washington, D.C., area and focuses on the city's lost springs. Until 150 years ago, springs and shallow dug wells were the main source of drinking water for residents of Washington, D.C. Celebrating the nation's bicentennial, Garnett P. Williams of the U.S. Geological Survey examined changes in water supply and water courses since 1776. He examined old newspaper files to determine the location of the city's springs. This field trip visits sites of some of these springs (few of which are now flowing), discusses the hydrologic impacts of urbanization and the general geological setting, and finishes with the Baltimore Long Term Ecological Research site at Dead Run and its findings. The field trip visits some familiar locations in the Washington, D.C., area, and gives insights into their often hidden hydrologic past and present.

Etidronate

MedlinePlus

... the skeleton) in people who have had total hip replacement surgery (surgery to replace the hip joint with an artificial joint) or in people ... 8 ounces [180 to 240 mL]) of plain water while you are sitting or standing. Sit or ...

Science Advisory Board Evaluation of the Effectiveness of Partial Lead Service Line Replacements

EPA Pesticide Factsheets

Report of the Science Advisory Board (SAB) to evaluate the current scientific data to determine the effectiveness of partial lead service line replacements (PLSLR) in reducing drinking water lead levels.

Communication, perception and behaviour during a natural disaster involving a 'Do Not Drink' and a subsequent 'Boil Water' notice: a postal questionnaire study.

PubMed

Rundblad, Gabriella; Knapton, Olivia; Hunter, Paul R

2010-10-25

During times of public health emergencies, effective communication between the emergency response agencies and the affected public is important to ensure that people protect themselves from injury or disease. In order to investigate compliance with public health advice during natural disasters, we examined consumer behaviour during two water notices that were issued as a result of serious flooding. During the summer of 2007, 140,000 homes in Gloucestershire, United Kingdom, that are supplied water from Mythe treatment works, lost their drinking water for up to 17 days. Consumers were issued a 'Do Not Drink' notice when the water was restored, which was subsequently replaced with a 'Boil Water' notice. The rare occurrence of two water notices provided a unique opportunity to compare compliance with public health advice. Information source use and other factors that may affect consumer perception and behaviour were also explored. A postal questionnaire was sent to 1,000 randomly selected households. Chi-square, ANOVA, MANOVA and generalised estimating equation (with and without prior factor analysis) were used for quantitative analysis. In terms of information sources, we found high use of and clear preference for the local radio throughout the incident, but family/friends/neighbours also proved crucial at the onset. Local newspapers and the water company were associated with clarity of advice and feeling informed, respectively. Older consumers and those in paid employment were particularly unlikely to read the official information leaflets. We also found a high degree of confusion regarding which notice was in place at which time, with correct recall varying between 23.2%-26.7%, and a great number of consumers believed two notices were in place simultaneously. In terms of behaviour, overall non-compliance levels were significantly higher for the 'Do Not Drink' notice (62.9%) compared to the 'Boil Water' notice (48.3%); consumers in paid employment were not likely to comply with advice. Non-compliance with the general advice to boil bowser water was noticeably lower (27.3%). Higher non-compliance during the 'Do Not Drink' notice was traced to the public's limited knowledge of water notices and their folk beliefs about the protection offered from boiling water. We suggest that future information dissemination plans reduce reliance on official leaflets and maximise the potential of local media and personal networks. Current public health education programmes are recommended to attend to insufficient and incorrect public knowledge about precautionary actions.

Communication, perception and behaviour during a natural disaster involving a 'Do Not Drink' and a subsequent 'Boil Water' notice: a postal questionnaire study

PubMed Central

2010-01-01

Background During times of public health emergencies, effective communication between the emergency response agencies and the affected public is important to ensure that people protect themselves from injury or disease. In order to investigate compliance with public health advice during natural disasters, we examined consumer behaviour during two water notices that were issued as a result of serious flooding. During the summer of 2007, 140,000 homes in Gloucestershire, United Kingdom, that are supplied water from Mythe treatment works, lost their drinking water for up to 17 days. Consumers were issued a 'Do Not Drink' notice when the water was restored, which was subsequently replaced with a 'Boil Water' notice. The rare occurrence of two water notices provided a unique opportunity to compare compliance with public health advice. Information source use and other factors that may affect consumer perception and behaviour were also explored. Method A postal questionnaire was sent to 1,000 randomly selected households. Chi-square, ANOVA, MANOVA and generalised estimating equation (with and without prior factor analysis) were used for quantitative analysis. Results In terms of information sources, we found high use of and clear preference for the local radio throughout the incident, but family/friends/neighbours also proved crucial at the onset. Local newspapers and the water company were associated with clarity of advice and feeling informed, respectively. Older consumers and those in paid employment were particularly unlikely to read the official information leaflets. We also found a high degree of confusion regarding which notice was in place at which time, with correct recall varying between 23.2%-26.7%, and a great number of consumers believed two notices were in place simultaneously. In terms of behaviour, overall non-compliance levels were significantly higher for the 'Do Not Drink' notice (62.9%) compared to the 'Boil Water' notice (48.3%); consumers in paid employment were not likely to comply with advice. Non-compliance with the general advice to boil bowser water was noticeably lower (27.3%). Conclusion Higher non-compliance during the 'Do Not Drink' notice was traced to the public's limited knowledge of water notices and their folk beliefs about the protection offered from boiling water. We suggest that future information dissemination plans reduce reliance on official leaflets and maximise the potential of local media and personal networks. Current public health education programmes are recommended to attend to insufficient and incorrect public knowledge about precautionary actions. PMID:20973959

Commercial Toilets

EPA Pesticide Factsheets

Whether you are looking to reduce water use in a new facility or replace old, inefficient toilets in commercial restrooms, a WaterSense labeled flushometer-valve toilet is a high-performance, water-efficient option worth considering.

3 micron spectrophotometry of Comet Halley - Evidence for water ice

NASA Technical Reports Server (NTRS)

Bregman, Jesse D.; Tielens, A. G. G. M.; Witteborn, Fred C.; Rank, David M.; Wooden, Diane

1988-01-01

Structure has been observed in the 3-3.6 micron preperihelion spectrum of Comet Halley consistent with either an absorption band near 3.1 microns or emission near 3.3 microns. The results suggest that a large fraction of the water molecules lost by the comet are initially ejected in the form of small ice particles rather than in the gas phase.

Methods to determine transit losses for return flows of transmountain water in Fountain Creek between Colorado Springs and the Arkansas River, Colorado

USGS Publications Warehouse

Kuhn, Gerhard

1988-01-01

Methods were developed by which transit losses could be determined for transmountain return flows in Fountain Creek between Colorado Springs, Colorado, and its confluence with the Arkansas River. The study reach is a complex hydrologic system wherein a substantially variable streamflow interacts with an alluvial aquifer. The study approach included: (1) calibration and verification of a streamflow-routing model that contained a bank-storage-discharge component; (2) use of the model to develop the methods by which transit losses could be calculated; and (3) design of an application method for calculating daily transit loss using the model results. Sources of transit losses that were studied are bank storage, channel storage, and evaporation. Magnitude of bank-storage loss primarily depends on duration of a recovery period during which water lost to bank storage is returned to the stream. Net loss to bank storage can vary from about 50% for a 0-day recovery period to about 2% for a 180-day recovery period. Virtually all water lost to bank storage could be returned to the stream with longer recovery periods. Channel-storage loss was determined to be about 10% of a release quantity. Because the loss on any given day is totally recovered in the form of gains from channel storage on the subsequent day, channel storage is a temporary transit loss. Evaporation loss generally is less than 5% of a given daily transmountain return-flow release, depending on month of year. Evaporation losses are permanently lost from the system. (USGS)

Cellular replacement therapy for Parkinson's disease--where we are today?

PubMed

Redmond, D Eugene

2002-10-01

The concept of replacing lost dopamine neurons in Parkinson's disease using mesencephalic brain cells from fetal cadavers has been supported by over 20 years of research in animals and over a decade of clinical studies. The ambitious goal of these studies was no less than a molecular and cellular "cure" for Parkinson's disease, other neurodegenerative diseases, and spinal cord injury. Much research has been done in rodents, and a few studies have been done in nonhuman primate models. Early uncontrolled clinical reports were enthusiastic, but the outcome of the first randomized, double blind, controlled study challenged the idea that dopamine replacement cells can cure Parkinson's disease, although there were some significant positive findings. Were the earlier animal studies and clinical reports wrong? Should we give up on the goal? Some aspects of the trial design and implantation methods may have led to lack of effects and to some side effects such as dyskinesias. But a detailed review of clinical neural transplants published to date still suggests that neural transplantation variably reverses some aspects of Parkinson's disease, although differing methods make exact comparisons difficult. While the randomized clinical studies have been in progress, new methods have shown promise for increasing transplant survival and distribution, reconstructing the circuits to provide dopamine to the appropriate targets and with normal regulation. Selected promising new strategies are reviewed that block apoptosis induced by tissue dissection, promote vascularization of grafts, reduce oxidant stress, provide key growth factors, and counteract adverse effects of increased age. New sources of replacement cells and stem cells may provide additional advantages for the future. Full recovery from parkinsonism appears not only to be possible, but a reliable cell replacement treatment may finally be near.

Language in tuberculosis services: can we change to patient-centred terminology and stop the paradigm of blaming the patients?

PubMed

Zachariah, R; Harries, A D; Srinath, S; Ram, S; Viney, K; Singogo, E; Lal, P; Mendoza-Ticona, A; Sreenivas, A; Aung, N W; Sharath, B N; Kanyerere, H; van Soelen, N; Kirui, N; Ali, E; Hinderaker, S G; Bissell, K; Enarson, D A; Edginton, M E

2012-06-01

The words 'defaulter', 'suspect' and 'control' have been part of the language of tuberculosis (TB) services for many decades, and they continue to be used in international guidelines and in published literature. From a patient perspective, it is our opinion that these terms are at best inappropriate, coercive and disempowering, and at worst they could be perceived as judgmental and criminalising, tending to place the blame of the disease or responsibility for adverse treatment outcomes on one side-that of the patients. In this article, which brings together a wide range of authors and institutions from Africa, Asia, Latin America, Europe and the Pacific, we discuss the use of the words 'defaulter', 'suspect' and 'control' and argue why it is detrimental to continue using them in the context of TB. We propose that 'defaulter' be replaced with 'person lost to follow-up'; that 'TB suspect' be replaced by 'person with presumptive TB' or 'person to be evaluated for TB'; and that the term 'control' be replaced with 'prevention and care' or simply deleted. These terms are non-judgmental and patient-centred. We appeal to the global Stop TB Partnership to lead discussions on this issue and to make concrete steps towards changing the current paradigm.

Generation of diverse neural cell types through direct conversion

PubMed Central

Petersen, Gayle F; Strappe, Padraig M

2016-01-01

A characteristic of neurological disorders is the loss of critical populations of cells that the body is unable to replace, thus there has been much interest in identifying methods of generating clinically relevant numbers of cells to replace those that have been damaged or lost. The process of neural direct conversion, in which cells of one lineage are converted into cells of a neural lineage without first inducing pluripotency, shows great potential, with evidence of the generation of a range of functional neural cell types both in vitro and in vivo, through viral and non-viral delivery of exogenous factors, as well as chemical induction methods. Induced neural cells have been proposed as an attractive alternative to neural cells derived from embryonic or induced pluripotent stem cells, with prospective roles in the investigation of neurological disorders, including neurodegenerative disease modelling, drug screening, and cellular replacement for regenerative medicine applications, however further investigations into improving the efficacy and safety of these methods need to be performed before neural direct conversion becomes a clinically viable option. In this review, we describe the generation of diverse neural cell types via direct conversion of somatic cells, with comparison against stem cell-based approaches, as well as discussion of their potential research and clinical applications. PMID:26981169

40 CFR 86.162-00 - Approval of alternative air conditioning test simulations and descriptions of AC1 and AC2.

Code of Federal Regulations, 2012 CFR

2012-07-01

... power requirements to roadload dynamometer requirements. AC2 simulates, in standard test cell ambient...)(i) (A) and (B) are replaced with 76 °F and 50 grains of water/pound of dry air and the solar heat...)(5)(i) (A) and (B) are replaced with 76 °F and 50 grains of water/pound of dry air and the solar heat...

40 CFR 86.162-00 - Approval of alternative air conditioning test simulations and descriptions of AC1 and AC2.

Code of Federal Regulations, 2013 CFR

2013-07-01

... power requirements to roadload dynamometer requirements. AC2 simulates, in standard test cell ambient...)(i) (A) and (B) are replaced with 76 °F and 50 grains of water/pound of dry air and the solar heat...)(5)(i) (A) and (B) are replaced with 76 °F and 50 grains of water/pound of dry air and the solar heat...

Stability of Proteins in Carbohydrates and Other Additives during Freezing: The Human Growth Hormone as a Case Study.

PubMed

Arsiccio, Andrea; Pisano, Roberto

2017-09-21

Molecular dynamics is here used to elucidate the mechanism of protein stabilization by carbohydrates and other additives during freezing. More specifically, we used molecular dynamics simulations to obtain a quantitative estimation of the capability of various cryoprotectants to preserve a model protein, the human growth hormone, against freezing stresses. Three mechanisms were investigated, preferential exclusion, water replacement, and vitrification. Model simulations were finally validated upon experimental data in terms of the ability of excipients to prevent protein aggregation. Overall, we found that the preferential exclusion and vitrification mechanisms are important during the whole freezing process, while water replacement becomes dominant only toward the end of the cryoconcentration phase. The disaccharides were found to be the most efficient excipients, in regard to both preferential exclusion and water replacement. Moreover, sugars were in general more efficient than other excipients, such as glycine or sorbitol.

Evaluation of ultrasonic cavitation of metallic and non-metallic surfaces

NASA Technical Reports Server (NTRS)

Mehta, Narinder K.

1992-01-01

1,1,2 trichloro-1,2,2 trifluoro ethane (CFC-113) commercially known as Freon-113 is the primary test solvent used for validating the cleaned hardware at the Kennedy Space Center (KSC). Due to the ozone depletion problem, the current United States policy calls for the phase out of Freons by 1995. NASAs chlorofluorocarbon (CFC) replacement group at KSC has opted to use water as a replacement fluid for the validation process since water is non-toxic, inexpensive, and is environmentally friendly. The replacement validation method calls for the ultrasonification of the small parts with water at 52 C for a cycle or two of 10 min duration wash using commercial ultrasonic baths. In this project, experimental data was obtained to assess the applicability of the proposed validation method for any damage of the metallic and non-metallic surfaces resulting from ultrasonic cavitation.

Production and Field Planting of Vegetative Propagules for Restoration of Redhead Grass and Sago Pondweed in Chesapeake Bay

DTIC Science & Technology

2009-08-01

submerged aquatic vegetation (SAV) have been lost from shallow waters of Chesapeake Bay (Orth and Moore 1983) and other coastal ecosystems worldwide...a mixture of ambient estuarine water from the Choptank River (a tributary of Chesapeake Bay) and freshwater (tap) needed to maintain a salinity of 7...with a mixture of freshwater and ambient estuarine water (to maintain a salinity of 10) that was circulated through a closed- loop recirculation system

MX Siting Investigation. Volume IIC. Geotechnical Report, Nellis Air Force Base Bombing and Gunnery Range (NBGR).

DTIC Science & Technology

1975-06-30

water holes in the mountain areas (Colton, 1965; Thordarson and Robinson, 1971; Winograd and others, 1971). Surface water conditions within NBGR are...gpm) to a maximum of over 400 gpm at Indian Spring ( Thordarson and Robinson, 1971). Most spring water not retained in catchments is lost to either...The earthquakes of Nevada and the tidal forces: Jour. Geophys. Research, v. 73, no. 18, p. 6013-6018. * Thordarson , W., and Robinson, B. P., 1971

Mass Reduction: The Weighty Challenge for Exploration Space Flight

NASA Technical Reports Server (NTRS)

Kloeris, Vickie L.

2014-01-01

Meeting nutritional and acceptability requirements is critical for the food system for an exploration class space mission. However, this must be achieved within the constraints of available resources such as water, crew time, stowage volume, launch mass and power availability. ? Due to resource constraints, exploration class missions are not expected to have refrigerators or freezers for food storage, and current per person food mass must be reduced to improve mission feasibility. ? The Packaged Food Mass Reduction Trade Study (Stoklosa, 2009) concluded that the mass of the current space food system can be effectively reduced by decreasing water content of certain foods and offering nutrient dense substitutes, such as meal replacement bars and beverages. Target nutrient ranges were established based on the nutritional content of the current breakfast and lunch meals in the ISS standard menu. A market survey of available commercial products produced no viable options for meal replacement bar or beverage products. New prototypes for both categories were formulated to meet target nutrient ranges. Samples of prototype products were packaged in high barrier packaging currently used for ISS and underwent an accelerated shelf life study at 31 degC and 41 degC (50% RH) for 24 weeks. Samples were assessed at the following time points: Initial, 6 weeks, 12 weeks, and 24 weeks. Testing at each time point included the following: color, texture, water activity, acceptability, and hexanal analysis (for food bars only). Proof of concept prototypes demonstrated that meal replacement food bars and beverages can deliver a comparable macronutrient profile while reducing the overall mass when compared to the ISS Standard Menu. Future work suggestions for meal replacement bars: Reformulation to include ingredients that reduce hardness and reduce browning to increase shelf life. Micronutrient analysis and potential fortification. Sensory evaluation studies including satiety tests and menu fatigue. Water Intake Analysis: The water in thermostabilized foods is considered as part of a crewmember's daily water intake. Extensive meal replacement would require further analyses to determine if additional water provisioning would be required per crewmember negating some of the mass savings.

Constituents of smoke from cigarettes made from diverted nicotine replacement therapy patches.

PubMed

Morrissey, Hana; Ball, Patrick; Boland, Martin; Hefler, Marita; Thomas, David P

2016-03-01

Anecdotes of nicotine replacement therapy patch misuse associated with the introduction of smoke-free prisons have been reported by media internationally, including Canada in 2006, New Zealand in 2011 and Australia in 2014. This study identifies chemical compounds released through diverted nicotine replacement therapy patches when they are smoked. Two samples were produced: (i) shredded 21 mg nicotine replacement therapy patches rolled with tea leaves into a cigarette; and (ii) patches boiled in water and tea leaves, and then dried tea leaves rolled into a cigarette. The smoke was tested for nicotine, caffeine and toxins. High-performance liquid chromatography, mass spectrometry and spectrophotometry were used to detect the presence and quantity of nicotine and caffeine. A specialised laboratory was contracted to test the presence of toxins. Nicotine was liberated when the two samples were burnt but not if the nicotine replacement therapy patches were boiled in water alone. High concentrations of formaldehyde, acetaldehyde, acrolein, toluene, xylene and heavy metals were also released. Nicotine is released when diverted nicotine replacement therapy patches are smoked, as are caffeine and harmful toxins. These toxins have the potential to cause short- and long-term health damage. © 2015 Australasian Professional Society on Alcohol and other Drugs.

Residential Toilets

EPA Pesticide Factsheets

By replacing old, inefficient toilets with WaterSense labeled models, the average family can reduce water used for toilets by 20 to 60 percent—that's nearly 13,000 gallons of water savings for your home every year!

International Space Station (ISS) Orbital Replaceable Unit (ORU) Wet Storage Risk Assessment

NASA Technical Reports Server (NTRS)

Squire, Michael D.; Rotter, Henry A.; Lee, Jason; Packham, Nigel; Brady, Timothy K.; Kelly, Robert; Ott, C. Mark

2014-01-01

The International Space Station (ISS) Program requested the NASA Engineering and Safety Center (NESC) to evaluate the risks posed by the practice of long-term wet storage of ISS Environmental Control and Life Support (ECLS) regeneration system orbital replacement units (ORUs). The ISS ECLS regeneration system removes water from urine and humidity condensate and converts it into potable water and oxygen. A total of 29 ORUs are in the ECLS system, each designed to be replaced by the ISS crew when necessary. The NESC assembled a team to review the ISS ECLS regeneration system and evaluate the potential for biofouling and corrosion. This document contains the outcome of the evaluation.

75 FR 7411 - Schedule of Water Charges

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-19

... sale revenues, while the costs of reservoir maintenance and operations, contractual services and..., ``including debt service, operation, maintenance, replacement, reserves, and associated administrative costs... holds funds dedicated to pay the costs of project construction, operation, maintenance, and replacement...

Town Flush with Benefits from New Water System

EPA Pesticide Factsheets

An EPA-funded project to replace the aging and undersized water lines in a Virginia town has transformed the community–providing cost savings, improved water quality and greater public safety, while eliminating leaks that drained half of the town' water.

An Evaluation of Technology to Remove Problematic Organic Compounds from the International Space Station Potable Water

NASA Technical Reports Server (NTRS)

Rector, Tony; Metselaar, Carol; Peyton, Barbara; Steele, John; Michalek, William; Bowman, Elizabeth; Wilson, Mark; Gazda, Daniel; Carter, Layne

2014-01-01

Since activation of the Water Processor Assembly (WPA) on the International Space Station (ISS) in November of 2008, there have been three events in which the TOC (Total Organic Carbon) in the product water has increased to approximately 3 mg/L and has subsequently recovered. Analysis of the product water in 2010 identified the primary component of the TOC as dimethylsilanediol (DMSD). An investigation into the fate of DMSD in the WPA ultimately determined that replacement of both Multifiltration (MF) Beds is the solution to recovering product water quality. The MF Beds were designed to ensure that ionic breakthrough occurs before organic breakthrough. However, DMSD saturated both MF Beds in the series, requiring removal and replacement of both MF Beds with significant life remaining. Analysis of the MF Beds determined that the adsorbent was not effectively removing DMSD, trimethylsilanol, various polydimethylsiloxanes, or dimethylsulfone. Coupled with the fact that the current adsorbent is now obsolete, the authors evaluated various media to identify a replacement adsorbent as well as media with greater capacity for these problematic organic contaminants. This paper provides the results and recommendations of this collaborative study.

Preparation and impact of multiple (water-in-oil-in-water) emulsions in meat systems.

PubMed

Cofrades, S; Antoniou, I; Solas, M T; Herrero, A M; Jiménez-Colmenero, F

2013-11-01

The aim of this paper was to prepare and characterise multiple emulsions and assess their utility as pork backfat replacers in meat gel/emulsion model systems. In order to improve the fat content (in quantitative and qualitative terms) pork backfat was replaced by a water-in-oil-in-water emulsion (W1/O/W2) prepared with olive oil (as lipid phase), polyglycerol ester of polyricinoleic acid (PGPR) as a lipophilic emulsifier, and sodium caseinate (SC) and whey protein concentrate (WP) as hydrophilic emulsifiers. The emulsion properties (particle size and distribution, stability, microstructure) and meat model system characteristics (composition, texture, fat and water binding properties, and colour) of the W1/O/W2, as affected by reformulation, were evaluated. Multiple emulsions showed a well-defined monomodal distribution. Freshly prepared multiple emulsions showed good thermal stability (better using SC) with no creaming. The meat systems had good water and fat binding properties irrespective of formulation. The effect on texture by replacement of pork backfat by W1/O/W2 emulsions generally depends on the type of double emulsion (associated with the hydrophilic emulsifier used in its formulation) and the fat level in the meat system. Copyright © 2013 Elsevier Ltd. All rights reserved.

Laser induced photoreceptor damage and recovery in the high numerical aperture eye of the garter snake.

PubMed

Zwick, H; Edsall, P; Stuck, B E; Wood, E; Elliott, R; Cheramie, R; Hacker, H

2008-02-01

The garter snake provides a unique model for in-vivo imaging of photoreceptor damage induced by laser retinal exposure. Laser thermal/mechanical retinal injury induced alterations in photoreceptor structure and leukocyte cellular behavior. Photoreceptors turned white, lost mode structure, and swelled; leukocyte activity was observed in the vicinity of photoreceptor cells. Non-thermal alterations were identified with a bio-tag for oxidative stress. Mechanisms of photoreceptor recovery and replacement were observed and evaluated for active cytoskeletal systems by using an anti-actin tag that could detect the presence of active cytoskeletal systems resident in photoreceptors as well as other retinal systems.

Premium Efficiency Motor Selection and Application Guide – A Handbook for Industry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gilbert A. McCoy and John G. Douglass

2014-02-01

This handbook informs new motor purchase decisions by identifying energy and cost savings that can come from replacing motors with premium efficiency units. The handbook provides an overview of current motor use in the industrial sector, including the development of motor efficiency standards, currently available and emerging advanced efficiency motor technologies, and guidance on how to evaluate motor efficiency opportunities. It also several tips on getting the most out of industrial motors, such as how to avoid adverse motor interactions with electronic adjustable speed drives and how to ensure efficiency gains are not lost to undervoltage operation or excessive voltagemore » unbalance.« less

Tibial rotation kinematics subsequent to knee arthroplasty

PubMed Central

Collins, Duane J.; Khatib, Yasser H.; Parker, David A.; Jenkin, Deanne E.; Molnar, Robert B.

2015-01-01

Background The use of computer assisted joint replacement has facilitated precise intraoperative measurement of knee kinematics. The changes in “screw home mechanism” (SHM) resulting from Total Knee Arthroplasty (TKA) with different prostheses and constraints has not yet been accurately described. Methods A pilot study was first completed. Intraoperative kinematic data was collected two groups of 15 patients receiving different prostheses. Results On average, patients lost 5.3° of ER (SD = 6.1°). There was no significant difference between the prostheses or different prosthetic constraints. Conclusions There significant loss of SHM after TKA. Further research is required to understand its impact on patient function. PMID:25829754

Investigate methods for measuring muscle and bone mass changes in astronauts and animals which occur during space flight

NASA Technical Reports Server (NTRS)

Palmer, H. E.

1977-01-01

Sodium-22 is being used as a tracer for bone mineral metabolism studies. Dogs are being grown from puppies to adulthood on a diet containing a constant level of sodium-22 in order to uniformly tag the entire skeleton with a long lived radionuclide. This study is still in progress and the dogs are still growing. Potassium-40 measurements were made on people, who are replacing muscle mass lost due to leg injuries, in a second study. It appears that potassium-40 measurements provide an accurate and convenient method for determining relative changes in the muscle content of the leg.

NASA seeks to revive lost probe that traced solar storms

NASA Astrophysics Data System (ADS)

Voosen, Paul

2018-02-01

NASA's Imager for Magnetopause-to-Aurora Global Exploration (IMAGE), a satellite that failed in 2005, was recently discovered to be reactivated by an amateur astronomer. Until its demise, IMAGE provided unparalleled views of solar storms crashing into Earth's magnetosphere, a capability that has not been replaced since. The amateur astronomer was on the search for Zuma, a classified U.S. satellite that's believed to have failed after launch. He instead discovered IMAGE, broadcasting again, likely thanks to a reboot that occurred after its batteries drained during a past solar eclipse. NASA scientists are now working to communicate with the satellite in the hopes of reviving its six scientific instruments.

Simulation of streamflow and the effects of brush management on water yields in the upper Guadalupe River watershed, south-central Texas, 1995-2010

USGS Publications Warehouse

Bumgarner, Johnathan R.; Thompson, Florence E.

2012-01-01

The U.S. Geological Survey, in cooperation with the Texas State Soil and Water Conservation Board and the Upper Guadalupe River Authority, developed and calibrated a Soil and Water Assessment Tool watershed model of the upper Guadalupe River watershed in south-central Texas to simulate streamflow and the effects of brush management on water yields in the watershed and to Canyon Lake for 1995-2010. Model simulations were done to quantify the possible change in water yield of individual subbasins in the upper Guadalupe River watershed as a result of the replacement of ashe juniper (Juniperus ashei) with grasslands. The simulation results will serve as a tool for resource managers to guide their brush-management efforts. Model hydrology was calibrated with streamflow data collected at the U.S. Geological Survey streamflow-gaging station 08167500 Guadalupe River near Spring Branch, Tex., for 1995-2010. Simulated monthly streamflow showed very good agreement with measured monthly streamflow: a percent bias of -5, a coefficient of determination of 0.91, and a Nash-Sutcliffe coefficient of model efficiency of 0.85. Modified land-cover input datasets were generated for the model in order to simulate the replacement of ashe juniper with grasslands in 23 brush-management subbasins in the watershed. Each of the 23 simulations showed an increase in simulated water yields in the targeted subbasins and to Canyon Lake. The simulated increases in average annual water yields in the subbasins ranged from 6,370 to 119,000 gallons per acre of ashe juniper replaced with grasslands with an average of 38,900 gallons. The simulated increases in average annual water yields to Canyon Lake from upstream subbasins ranged from 6,640 to 72,700 gallons per acre of ashe juniper replaced with grasslands with an average of 34,700 gallons.

Estimated community costs of an outbreak of campylobacteriosis resulting from contamination of a public water supply in Darfield, New Zealand.

PubMed

Sheerin, Ian; Bartholomew, Nadia; Brunton, Cheryl

2014-03-28

To estimate the economic costs to the community of an outbreak of campylobacteriosis in August 2012 resulting from contamination of a public water supply in Darfield, New Zealand. Probable incidence of waterborne disease was estimated. Reported cases were scrutinised to identify symptoms, duration, hospital admissions and those in the paid workforce. Extra public health and local authority costs were calculated. Estimated time off work was multiplied by the average wage to obtain a conservative estimate of lost production. Sensitivity analysis was used to estimate unreported cases and their associated costs. There were 138 cases of confirmed or probable campylobacter, of whom 46 sought a medical consultation. Taking into account the usual pyramid of non-notified cases, estimates of the population infected range between approximately 828 and 1987. The dominant societal cost is lost production from time off paid work. Forty-six per cent were in the paid workforce, indicating a total estimated economic cost of at least $714,527 but it could have been as high as $1.26 million, depending on estimates of unreported cases. The likely cause of the Darfield outbreak was faecal contamination of the water supply, which with a multi-barrier approach would have been entirely preventable. The results provide economic evidence to support upgrading of water supplies to provide safe water and prevent waterborne disease.

Legacy and Emerging Perfluoroalkyl Substances Are ...

EPA Pesticide Factsheets

Long-chain per- and polyfluoroalkyl substances (PFASs) are being replaced by short-chain PFASs and fluorinated alternatives. For ten legacy PFASs and seven recently discovered perfluoroalkyl ether carboxylic acids (PFECAs), we report (1) their occurrence in the Cape Fear River (CFR) watershed, (2) their fate in water treatment processes, and (3) their adsorbability on powdered activated carbon (PAC). In the headwater region of the CFR basin, PFECAs were not detected in raw water of a drinking water treatment plant (DWTP), but concentrations of legacy PFASs were high. The U.S. Environmental Protection Agency’s lifetime health advisory level (70 ng/L) for perfluorooctanesulfonic acid and perfluorooctanoic acid (PFOA) was exceeded on 57 of 127 sampling days. In raw water of a DWTP downstream of a PFAS manufacturer, the mean concentration of perfluoro-2-propoxypropanoic acid (PFPrOPrA), a replacement for PFOA, was 631 ng/L (n = 37). Six other PFECAs were detected, with three exhibiting chromatographic peak areas up to 15 times that of PFPrOPrA. At this DWTP, PFECA removal by coagulation, ozonation, biofiltration, and disinfection was negligible. The adsorbability of PFASs on PAC increased with increasing chain length. Replacing one CF2 group with an ether oxygen decreased the affinity of PFASs for PAC, while replacing additional CF2 groups did not lead to further affinity changes. The USEPA’s recently completed Unregulated Contaminant Monitoring Rule 3 (UCMR3) p

Dependence of flow and transport through the Williamson River Delta, Upper Klamath Lake, Oregon, on wind, river inflow, and lake elevation

USGS Publications Warehouse

Wood, Tamara M.

2012-01-01

The hydrodynamic model of Upper Klamath and Agency Lakes, Oregon, was used to run 384 realizations of a numerical tracer experiment in order to understand the relative effects of wind, lake elevation, and Williamson River inflow on flow and transport (the movement of water and passively transported constituents) through the Williamson River Delta. Significant findings from this study include: * The replacement rate of water increased in Tulana and Goose Bay with increasing lake elevation, Williamson River inflow, and wind speed. * The fraction of Williamson River inflow passing through either side of the Delta increased with lake elevation and Williamson River inflow. * The partial replacement rate of water in Goose Bay with water from the Williamson River increased with wind speed. * The partial replacement rate of water in Tulana with water from the Williamson River decreased with wind speed. * Strong wind forcing at the water surface caused more of the Williamson River inflow to pass through Goose Bay than through Tulana. * Westerly to northwesterly winds result in more of the Williamson River inflow passing through the Goose Bay side of the Delta than through the Tulana side. * Regression models developed from the tracer experiments can be used to quantify the dependencies between transport and the independent variables to obtain rough estimates of useful quantities such as residence time and steady-state solute concentrations.

Use of a GIS-based hybrid artificial neural network to prioritize the order of pipe replacement in a water distribution network.

PubMed

Ho, Cheng-I; Lin, Min-Der; Lo, Shang-Lien

2010-07-01

A methodology based on the integration of a seismic-based artificial neural network (ANN) model and a geographic information system (GIS) to assess water leakage and to prioritize pipeline replacement is developed in this work. Qualified pipeline break-event data derived from the Taiwan Water Corporation Pipeline Leakage Repair Management System were analyzed. "Pipe diameter," "pipe material," and "the number of magnitude-3( + ) earthquakes" were employed as the input factors of ANN, while "the number of monthly breaks" was used for the prediction output. This study is the first attempt to manipulate earthquake data in the break-event ANN prediction model. Spatial distribution of the pipeline break-event data was analyzed and visualized by GIS. Through this, the users can swiftly figure out the hotspots of the leakage areas. A northeastern township in Taiwan, frequently affected by earthquakes, is chosen as the case study. Compared to the traditional processes for determining the priorities of pipeline replacement, the methodology developed is more effective and efficient. Likewise, the methodology can overcome the difficulty of prioritizing pipeline replacement even in situations where the break-event records are unavailable.

Species replacement dominates megabenthos beta diversity in a remote seamount setting.

PubMed

Victorero, Lissette; Robert, Katleen; Robinson, Laura F; Taylor, Michelle L; Huvenne, Veerle A I

2018-03-07

Seamounts are proposed to be hotspots of deep-sea biodiversity, a pattern potentially arising from increased productivity in a heterogeneous landscape leading to either high species co-existence or species turnover (beta diversity). However, studies on individual seamounts remain rare, hindering our understanding of the underlying causes of local changes in beta diversity. Here, we investigated processes behind beta diversity using ROV video, coupled with oceanographic and quantitative terrain parameters, over a depth gradient in Annan Seamount, Equatorial Atlantic. By applying recently developed beta diversity analyses, we identified ecologically unique sites and distinguished between two beta diversity processes: species replacement and changes in species richness. The total beta diversity was high with an index of 0.92 out of 1 and was dominated by species replacement (68%). Species replacement was affected by depth-related variables, including temperature and water mass in addition to the aspect and local elevation of the seabed. In contrast, changes in species richness component were affected only by the water mass. Water mass, along with substrate also affected differences in species abundance. This study identified, for the first time on seamount megabenthos, the different beta diversity components and drivers, which can contribute towards understanding and protecting regional deep-sea biodiversity.

Regenerating an Arsenic Removal Iron-Based Adsorptive ...

EPA Pesticide Factsheets

The replacement of exhausted, adsorptive media used to remove arsenic from drinking water accounts for approximately 80% of the total operational and maintenance (O/M) costs of this commonly used small system technology. The results of three, full scale system studies of an on-site media regeneration process (Part 1) showed it to be effective in stripping arsenic and other contaminants from the exhausted media. Part 2, of this two part paper, presents information on the performance of the regenerated media to remove arsenic through multiple regeneration cycles (3) and the approximate cost savings of regeneration over media replacement. The results of the studies indicate that regenerated media is very effective in removing arsenic and the regeneration cost is substantially less than the media replacement cost. On site regeneration, therefore, provides small systems with alternative to media replacement when removing arsenic from drinking water using adsorptive media technology. Part 2 of a two part paper on the performance of the regenerated media to remove arsenic through multiple regeneration cycles (3) and the approximate cost savings of regeneration over media replacement.

A saving solution.

PubMed

Mckee, N

1983-10-01

Dr. Mujibur Rahaman, senior scientist at the International Center for Diarrheal Disease Research in Bangladesh, was interviewed recently in regard to oral rehydration therapy (ORT), a simple and inexpensive way of treating the loss of essential fluids and minerals that accompanies diarrhea. According to Rahaman, ORT, developed quite a while ago, is recently gaining more publicity and wider acceptance as a menas of replacing the water and electrolytes lost during acute diarrhea attack. The standard ingredients of the ORT mixture, as it is used in Bangladesh, are 3.5 gm of sodium chloride, or common salt, 2.5 gm sodium bicarbonate, and 1 gm of potassium chloride. To this one should add either 20 gm of glucose or 40 gm of sugar. This mixture should be dissolved in 1 liter of plain drinking water. Plain sugar is good enough. How much is needed depends on the severity and the duration of diarrhea. Calculations have shown that, as a rule of thumb, a child of 10-12 kg may require little more than a liter in about 24 hours. If the child has diarrhea of sufficient severity, it may require more than a liter. If the diarrhea is prolonged, it may require 2 liters. For children who are in danger of dying from dehydration, parents are warned to be watchful because further treatment and follow-up may be required. In Bangladesh a national program is currently providing the ORT in remote rural areas. At present about 1/3 of Bangladesh is covered. The national health service is distributing the solution free of cost in the villages where they have health volunteers. Although ORT is simple to make and simple to administer, one has to exercise some degree of caution with it in order to prevent infants getting dangerous symptoms like hypernatremia. ORT makes it possible for health educators to enter into the family. It is not totally correct to say water is the main problem or causative factor in producing diarrhea. In infantile diarrhea, the cause is most often a virus. Viral transmission is not associated with water. Water can affect the incidence of diarrhea in several ways. The mother's hygiene can be affected by the availability of water, not just the quality but also the quantity. A most exciting study going on now is measuring the impact of water and sanitation on diarrheal diseases.

NEUTRONIC REACTOR WITH ACCESSIBLE THIMBLE AND EMERGENCY COOLING FEATURES

DOEpatents

McCorkle, W.H.

1960-02-23

BS>A safety system for a water-moderated reactor is described. The invention comprises a reservoir system for spraying the fuel elements within a fuel assembly with coolant and keeping them in a continuous bath even if the coolant moderator is lost from the reactor vessel. A reservoir gravity feeds one or more nozzels positioned within each fuel assembly which continually forces water past the fuel elements.

Continuous recording of excretory water loss from Musca domestica using a flow-through humidity meter: hormonal control of diuresis.

PubMed

Coast, Geoffrey M

2004-05-01

Water loss from adult male houseflies was continuously recorded using a flow-through humidity meter, which enabled losses to be apportioned between the sum of cuticular and respiratory transpiration, salivation and excretion. Transpiration accounted for >95% of water lost from sham-injected flies, compared with excretion (3.0%) and salivation (2.4%). In contrast, excretion accounted for 40% of water lost from flies injected with > or =3 microl of saline, whereas salivary losses were unchanged. Saline injections (1-5 microl) expanded the abdomen in the dorsal-ventral plane, and this expansion was positively correlated with the magnitude of the ensuing diuresis, suggesting the signal for diuretic hormone release originates from stretch receptors in abdominal tergal-sternal muscles. The effects of decapitation, severing the ventral nerve cord within the neck or ligaturing the neck, showed the head was needed to initiate and maintain diuresis, but was neither the source of diuretic hormone nor did it control the discharge of urine from the anus. These findings indicate the head is part of the neural-endocrine pathway between abdominal stretch receptors and sites for diuretic hormone release from the thoracic-abdominal ganglion mass. Evidence is presented for Musdo-K having a hormonal role in the control of diuresis, although other neuropeptides may also be implicated.

Sustained Water Loss in California's Mountain Ranges During Severe Drought From 2012 to 2015 Inferred From GPS

NASA Astrophysics Data System (ADS)

Argus, Donald F.; Landerer, Felix W.; Wiese, David N.; Martens, Hilary R.; Fu, Yuning; Famiglietti, James S.; Thomas, Brian F.; Farr, Thomas G.; Moore, Angelyn W.; Watkins, Michael M.

2017-12-01

Drought struck California during 7 of the 9 years from 2007 to 2015, reducing the state's available water resources. Pumping of Central Valley groundwater has produced spectacular land subsidence. Uplift of the adjacent Sierra Nevada mountains has been proposed to be either tectonic uplift or solid Earth's elastic response to unloading of Central Valley groundwater. We find that of the 24 mm of uplift of the Sierra Nevada from October 2011 to October 2015, just 5 mm is produced by Central Valley groundwater loss, less than 2 mm is tectonic uplift, and 17 mm is solid Earth's elastic response to water loss in the Sierra Nevada. We invert GPS vertical displacements recording solid Earth's elastic response to infer changes in water storage across the western U.S. from January 2006 to October 2017. We find water changes to be sustained over periods of drought or heavy precipitation: the Sierra Nevada lost 15 ± 19 km3 of water during drought from October 2006 to October 2009, gained 18 ± 14 km3 of water during heavy precipitation from October 2009 to October 2011, and lost 45 ± 21 km3 of water during severe drought from October 2011 to October 2015 (95% confidence limits). Such large changes are not in hydrology models: snow accumulation in October is negligible and long-term soil moisture change is small. We infer that there must be large loss of either deep soil moisture or groundwater in river alluvium and in crystalline basement in the Sierra Nevada. The results suggest there to be parching of water in the ground during the summer of years of drought and seeping of melting snow into the Sierra Nevada in the spring of years of heavy precipitation.

LEAK DETECTION AND WIRELESS TELEMETRY FOR WATER DISTRIBUTION AND SEWERAGE SYSTEMS - PHASE I

EPA Science Inventory

According to the study EPA 2000 Community Water System Survey Data on Pipe Assets, the infrastructure for water distribution and sewerage systems is aging and requires replacement.  In addition, in EPA’s September 2002 report Clean Water and Drinking Water Infr...