Electronic Repair Concepts for Long-Duration Spaceflight

NASA Technical Reports Server (NTRS)

Easton, John; Pettegrew, Richard D.; Struk, Peter M.

2007-01-01

Constraints on the mass and volume that can be allocated for electronics spares and repair equipment on long-duration space missions mean that NASA must look at repair strategies beyond the traditional approach, which has been to replace faulty subsystems in a modular form, termed Orbital Replacement Units or Line Replacement Units. Other possible strategies include component and board-level replacement, modular designs that allow reprogramming of less-critical systems to take the place of more critical failed systems, and a blended approach which uses elements of each of these approaches, along with a limited number of Line Replacement Units. This paper presents some of the constraints and considerations that affect the decision on how to approach electronics repair for long duration space missions, and discusses the benefits and limitations of each of the previously mentioned strategies.

Embedded piezoelectrics for sensing and energy harvesting in total knee replacement units

NASA Astrophysics Data System (ADS)

Wilson, Brooke E.; Meneghini, Michael; Anton, Steven R.

2015-04-01

The knee replacement is the second most common orthopedic surgical intervention in the United States, but currently only 1 in 5 knee replacement patients are satisfied with their level of pain reduction one year after surgery. It is imperative to make the process of knee replacement surgery more objective by developing a data driven approach to ligamentous balance, which increases implant life. In this work, piezoelectric materials are considered for both sensing and energy harvesting applications in total knee replacement implants. This work aims to embed piezoelectric material in the polyethylene bearing of a knee replacement unit to act as self-powered sensors that will aid in the alignment and balance of the knee replacement by providing intraoperative feedback to the surgeon. Postoperatively, the piezoelectric sensors can monitor the structural health of the implant in order to perceive potential problems before they become bothersome to the patient. Specifically, this work will present on the use of finite element modeling coupled with uniaxial compression testing to prove that piezoelectric stacks can be utilized to harvest sufficient energy to power sensors needed for this application.

Dynamic biomechanical examination of the lumbar spine with implanted total spinal segment replacement (TSSR) utilizing a pendulum testing system.

PubMed

Daniels, Alan H; Paller, David J; Koruprolu, Sarath; Palumbo, Mark A; Crisco, Joseph J

2013-01-01

Biomechanical investigations of spinal motion preserving implants help in the understanding of their in vivo behavior. In this study, we hypothesized that the lumbar spine with implanted total spinal segment replacement (TSSR) would exhibit decreased dynamic stiffness and more rapid energy absorption compared to native functional spinal units under simulated physiologic motion when tested with the pendulum system. Five unembalmed, frozen human lumbar functional spinal units were tested on the pendulum system with axial compressive loads of 181 N, 282 N, 385 N, and 488 N before and after Flexuspine total spinal segment replacement implantation. Testing in flexion, extension, and lateral bending began by rotating the pendulum to 5°; resulting in unconstrained oscillatory motion. The number of rotations to equilibrium was recorded and bending stiffness (N-m/°) was calculated and compared for each testing mode. The total spinal segment replacement reached equilibrium with significantly fewer cycles to equilibrium compared to the intact functional spinal unit at all loads in flexion (p<0.011), and at loads of 385 N and 488 N in lateral bending (p<0.020). Mean bending stiffness in flexion, extension, and lateral bending increased with increasing load for both the intact functional spinal unit and total spinal segment replacement constructs (p<0.001), with no significant differences in stiffness between the intact functional spinal unit and total spinal segment replacement in any of the test modes (p>0.18). Lumbar functional spinal units with implanted total spinal segment replacement were found to have similar dynamic bending stiffness, but absorbed energy at a more rapid rate than intact functional spinal units during cyclic loading with an unconstrained pendulum system. Although the effects on clinical performance of motion preserving devices is not fully known, these results provide further insight into the biomechanical behavior of this device under approximated physiologic loading conditions.

Dynamic Biomechanical Examination of the Lumbar Spine with Implanted Total Spinal Segment Replacement (TSSR) Utilizing a Pendulum Testing System

PubMed Central

Daniels, Alan H.; Paller, David J.; Koruprolu, Sarath; Palumbo, Mark A.; Crisco, Joseph J.

2013-01-01

Background Biomechanical investigations of spinal motion preserving implants help in the understanding of their in vivo behavior. In this study, we hypothesized that the lumbar spine with implanted total spinal segment replacement (TSSR) would exhibit decreased dynamic stiffness and more rapid energy absorption compared to native functional spinal units under simulated physiologic motion when tested with the pendulum system. Methods Five unembalmed, frozen human lumbar functional spinal units were tested on the pendulum system with axial compressive loads of 181 N, 282 N, 385 N, and 488 N before and after Flexuspine total spinal segment replacement implantation. Testing in flexion, extension, and lateral bending began by rotating the pendulum to 5°; resulting in unconstrained oscillatory motion. The number of rotations to equilibrium was recorded and bending stiffness (N-m/°) was calculated and compared for each testing mode. Results The total spinal segment replacement reached equilibrium with significantly fewer cycles to equilibrium compared to the intact functional spinal unit at all loads in flexion (p<0.011), and at loads of 385 N and 488 N in lateral bending (p<0.020). Mean bending stiffness in flexion, extension, and lateral bending increased with increasing load for both the intact functional spinal unit and total spinal segment replacement constructs (p<0.001), with no significant differences in stiffness between the intact functional spinal unit and total spinal segment replacement in any of the test modes (p>0.18). Conclusions Lumbar functional spinal units with implanted total spinal segment replacement were found to have similar dynamic bending stiffness, but absorbed energy at a more rapid rate than intact functional spinal units during cyclic loading with an unconstrained pendulum system. Although the effects on clinical performance of motion preserving devices is not fully known, these results provide further insight into the biomechanical behavior of this device under approximated physiologic loading conditions. PMID:23451222

Impact of the economic downturn on total joint replacement demand in the United States: updated projections to 2021.

PubMed

Kurtz, Steven M; Ong, Kevin L; Lau, Edmund; Bozic, Kevin J

2014-04-16

Few studies have explored the role of the National Health Expenditure and macroeconomics on the utilization of total joint replacement. The economic downturn has raised questions about the sustainability of growth for total joint replacement in the future. Previous projections of total joint replacement demand in the United States were based on data up to 2003 using a statistical methodology that neglected macroeconomic factors, such as the National Health Expenditure. Data from the Nationwide Inpatient Sample (1993 to 2010) were used with United States Census and National Health Expenditure data to quantify historical trends in total joint replacement rates, including the two economic downturns in the 2000s. Primary and revision hip and knee arthroplasty were identified using codes from the International Classification of Diseases, Ninth Revision, Clinical Modification. Projections in total joint replacement were estimated using a regression model incorporating the growth in population and rate of arthroplasties from 1993 to 2010 as a function of age, sex, race, and census region using the National Health Expenditure as the independent variable. The regression model was used in conjunction with government projections of National Health Expenditure from 2011 to 2021 to estimate future arthroplasty rates in subpopulations of the United States and to derive national estimates. The growth trend for the incidence of joint arthroplasty, for the overall United States population as well as for the United States workforce, was insensitive to economic downturns. From 2009 to 2010, the total number of procedures increased by 6.0% for primary total hip arthroplasty, 6.1% for primary total knee arthroplasty, 10.8% for revision total hip arthroplasty, and 13.5% for revision total knee arthroplasty. The National Health Expenditure model projections for primary hip replacement in 2020 were higher than a previously projected model, whereas the current model estimates for total knee arthroplasty were lower. Economic downturns in the 2000s did not substantially influence the national growth trends for hip and knee arthroplasty in the United States. These latest updated projections provide a basis for surgeons, hospitals, payers, and policy makers to plan for the future demand for total joint replacement surgery.

78 FR 21924 - Alabama Power Company; Notice of Application for Amendment of License and Soliciting Comments...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-12

... approval to replace the Unit 4 turbine at the Jordan Dam Project. Specifically, the licensee proposes the following work: complete turbine replacement, wicket gate system rehabilitation or replacement, gate stem bushing replacement, turbine and generator bearing refurbishment, and related component replacement. The...

Management of Microcircuit Obsolescence in a Pre-Production ACAT-ID Missile Program

DTIC Science & Technology

2002-12-01

and Engineering Center ASIC Application Specific Integrated Circuit AVCOM Avionics Component Obsolescence Management BRU Battery Replaceable Unit...then just a paper qualification, e.g. Board or Battery Replaceable Unit ( BRU ) testing. 5 After-market Package The Die is Available and Can Be...Encapsulated Microcircuits (PEM), speed change, failure rate) 8 Emulation Manufacture or re-engineering of a FFF Replacement 9 CCA or BRU Redesign Board

High efficiency novel window air conditioner

DOE PAGES

Bansal, Pradeep

2015-07-24

This paper presents the technical development of a high efficiency window air conditioner. In order to achieve higher energy efficiency ratio (EER), the original capacity of the R410A unit was downgraded by replacing the original compressor with a lower capacity but higher EER compressor, while all heat exchangers and the chassis from the original unit were retained. The other subsequent major modifications included – the AC fan motor being replaced with a brushless high efficiency electronically commuted motor (ECM) motor, the capillary tube being replaced with a needle valve to better control the refrigerant flow and refrigerant set points, andmore » R410A being replaced with drop-in environmentally friendly binary mixture of R32 (85% molar concentration)/R125 (15% molar concentration). All these modifications resulted in significant EER enhancement of the modified unit.« less

High efficiency novel window air conditioner

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bansal, Pradeep

This paper presents the technical development of a high efficiency window air conditioner. In order to achieve higher energy efficiency ratio (EER), the original capacity of the R410A unit was downgraded by replacing the original compressor with a lower capacity but higher EER compressor, while all heat exchangers and the chassis from the original unit were retained. The other subsequent major modifications included – the AC fan motor being replaced with a brushless high efficiency electronically commuted motor (ECM) motor, the capillary tube being replaced with a needle valve to better control the refrigerant flow and refrigerant set points, andmore » R410A being replaced with drop-in environmentally friendly binary mixture of R32 (85% molar concentration)/R125 (15% molar concentration). All these modifications resulted in significant EER enhancement of the modified unit.« less

30 CFR 7.69 - Approval marking.

Code of Federal Regulations, 2014 CFR

2014-07-01

... that the unit's components must not be disassembled or removed. (d) The replacement battery types if the unit has replaceable batteries. (e) A warning placed next to the charging connector that the battery only be charged in a fresh air location if rechargeable batteries are used. (f) A warning that the...

30 CFR 7.69 - Approval marking.

Code of Federal Regulations, 2010 CFR

2010-07-01

... that the unit's components must not be disassembled or removed. (d) The replacement battery types if the unit has replaceable batteries. (e) A warning placed next to the charging connector that the battery only be charged in a fresh air location if rechargeable batteries are used. (f) A warning that the...

30 CFR 7.69 - Approval marking.

Code of Federal Regulations, 2013 CFR

2013-07-01

... that the unit's components must not be disassembled or removed. (d) The replacement battery types if the unit has replaceable batteries. (e) A warning placed next to the charging connector that the battery only be charged in a fresh air location if rechargeable batteries are used. (f) A warning that the...

30 CFR 7.69 - Approval marking.

Code of Federal Regulations, 2011 CFR

2011-07-01

... that the unit's components must not be disassembled or removed. (d) The replacement battery types if the unit has replaceable batteries. (e) A warning placed next to the charging connector that the battery only be charged in a fresh air location if rechargeable batteries are used. (f) A warning that the...

30 CFR 7.69 - Approval marking.

Code of Federal Regulations, 2012 CFR

2012-07-01

... that the unit's components must not be disassembled or removed. (d) The replacement battery types if the unit has replaceable batteries. (e) A warning placed next to the charging connector that the battery only be charged in a fresh air location if rechargeable batteries are used. (f) A warning that the...

Mastracchio during EMU FPS Remove and Replace OPS

NASA Image and Video Library

2014-04-14

Expedition 39 flight engineer Rick Mastracchio poses for a photo with the replacement Fan Pump Separator (FPS) and Extravehicular Mobility Unit (EMU) 3005. Image was taken in the Quest Airlock (A/L) during FPS remove and replace operations.

24 CFR 42.375 - One-for-one replacement of lower-income dwelling units.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 1 2012-04-01 2012-04-01 false One-for-one replacement of lower-income dwelling units. 42.375 Section 42.375 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development DISPLACEMENT, RELOCATION ASSISTANCE, AND REAL PROPERTY...

24 CFR 42.375 - One-for-one replacement of lower-income dwelling units.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false One-for-one replacement of lower-income dwelling units. 42.375 Section 42.375 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development DISPLACEMENT, RELOCATION ASSISTANCE, AND REAL PROPERTY...

24 CFR 42.375 - One-for-one replacement of lower-income dwelling units.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false One-for-one replacement of lower-income dwelling units. 42.375 Section 42.375 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development DISPLACEMENT, RELOCATION ASSISTANCE, AND REAL PROPERTY...

24 CFR 42.375 - One-for-one replacement of lower-income dwelling units.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 1 2013-04-01 2013-04-01 false One-for-one replacement of lower-income dwelling units. 42.375 Section 42.375 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development DISPLACEMENT, RELOCATION ASSISTANCE, AND REAL PROPERTY...

24 CFR 42.375 - One-for-one replacement of lower-income dwelling units.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 1 2014-04-01 2014-04-01 false One-for-one replacement of lower-income dwelling units. 42.375 Section 42.375 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development DISPLACEMENT, RELOCATION ASSISTANCE, AND REAL PROPERTY...

The feasibility of replacing or upgrading utility distribution transformers during routine maintenance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barnes, P.R.; Van Dyke, J.W; McConnell, B.W.

It is estimated that electric utilities use about 40 million distribution transformers in supplying electricity to customers in the United States. Although utility distribution transformers collectively have a high average efficiency, they account for approximately 61 billion kWh of the 229 billion kWh of energy lost annually in the delivery of electricity. Distribution transformers are being replaced over time by new, more efficient, lower-loss units during routine utility maintenance of power distribution systems. Maintenance is typically not performed on units in service. However, units removed from service with appreciable remaining life are often refurbished and returned to stock. Distribution transformersmore » may be removed from service for many reasons, including failure, over- or underloading, or line upgrades such as voltage changes or rerouting. When distribution transformers are removed from service, a decision must be made whether to dispose of the transformer and purchase a lower-loss replacement or to refurbish the transformer and return it to stock for future use. This report contains findings and recommendations on replacing utility distribution transformers during routine maintenance, which is required by section 124 of the Energy Policy Act of 1992. The objectives of the study are to evaluate the practicability, cost-effectiveness, and potential energy savings of replacing or upgrading existing transformers during routine utility maintenance and to develop recommendations on ways to achieve the potential energy savings. Using survey data obtained from utilities and analyses of the economics of refurbishment versus replacement of distribution transformers that are removed from service, it is found that on average utilities are implementing reasonable decisions on refurbishment versus replacement.« less

Energy efficiency effect on the public street lighting by using LED light replacement and kwh-meter installation at DKI Jakarta Province, Indonesia

NASA Astrophysics Data System (ADS)

Sudarmono, Panggih; Deendarlianto; Widyaparaga, Adhika

2018-05-01

Public street lighting consumes large energy for the public interest, but many street lights still do not use energy-saving technologies. In 2014, Provincial Government of DKI Jakarta operated 179,305 units of street lights. Of the number of installed armature, 92 % of them or 166,441 units are HPS (High-Pressure Sodium) armatures which are inefficient. In 2016, the Provincial Government of DKI Jakarta cut down the energy used for street lighting, by implementing the programs of kWh-meter installation in every street lighting panel and use energy-saving lamps equipped with the smart system. The Provincial Government of DKI Jakarta is registered with 6,399 customer IDs in PLN (State Owned Electric Company), and gradually carried out the kWh Meter installation and changes to the contract. The program to use energy-saving lights done by replacing the HPS armature that is not energy efficient to LED armature which is known to be energy efficient. Until the end of 2016, the number of armatures that has been replaced was 89,417 units. The research results on 25 samples of PLN customer IDs and the replacement of 2,162 units armature, showed that the energy efficiency through kWh meter installation and armature replacement reduce the power consumption from 330,414 kWh to 71,278 kWh or by 78.43%. Generally, there was a decrease in the value of electricity bill compared to the before the replacement. The program of kWh-meter installations and replacement of the armature has a payback period of 2.66 years.

Electronics reliability fracture mechanics. Volume 1: Causes of failures of shop replaceable units and hybrid microcircuits

NASA Astrophysics Data System (ADS)

Kallis, J.; Buechler, D.; Erickson, J.; Westerhuyzen, D. V.; Strokes, R.

1992-05-01

This is the first of two volumes. The other volume (WL-TR-91-3119) is 'Fracture Mechanics'. The objective of the Electronics Reliability Fracture Mechanics (ERFM) program was to develop and demonstrate a life prediction technique for electronic assemblies, when subjected to environmental stress of vibration and thermal cycling, based upon the mechanical properties of the materials and packaging configurations which make up an electronic system. A detailed investigation was performed of the following two shop replaceable units (SRUs): Timing and Control Module (P/N 3562102) and Linear Regulator Module (P/N 3569800). The SRUs are in the Programmable Signal Processor (3137042) Line Replaceable Unit (LRU) of the Hughes AN/APG-63 Radar for the F-15 Aircraft.

The feasibility of replacing or upgrading utility distribution transformers during routine maintenance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barnes, P.R.; Van Dyke, J.W.; McConnell, B.W.

It is estimated that electric utilities use about 40 million distribution transformers in supplying electricity to customers in the United States. Although utility distribution transformers collectively have a high average efficiency, they account for approximately 61 billion kWh of the 229 billion kWh of energy lost annually in the delivery of electricity. Distribution transformers are being replaced over time by new, more efficient, lower-loss units during routine utility maintenance of power distribution systems. Maintenance is typically not performed on units in service. However, units removed from service with appreciable remaining life are often refurbished and returned to stock. Distribution transformersmore » may be removed from service for many reasons, including failure, over- or underloading, or line upgrades such as voltage changes or rerouting. When distribution transformers are removed from service, a decision must be made whether to dispose of the transformer and purchase a lower-loss replacement or to refurbish the transformer and return it to stock for future use. This report contains findings and recommendations on replacing utility distribution transformers during routine maintenance, which is required by section 124(c) of the Energy Policy Act of 1992. The objectives of the study are to evaluate the practicability, cost-effectiveness, and potential energy savings of replacing or upgrading existing transformers during routine utility maintenance and to develop recommendations on was to achieve the potential energy savings.« less

Monetary benefits of preventing childhood lead poisoning with lead-safe window replacement.

PubMed

Nevin, Rick; Jacobs, David E; Berg, Michael; Cohen, Jonathan

2008-03-01

Previous estimates of childhood lead poisoning prevention benefits have quantified the present value of some health benefits, but not the costs of lead paint hazard control or the benefits associated with housing and energy markets. Because older housing with lead paint constitutes the main exposure source today in the US, we quantify health benefits, costs, market value benefits, energy savings, and net economic benefits of lead-safe window replacement (which includes paint stabilization and other measures). The benefit per resident child from improved lifetime earnings alone is $21,195 in pre-1940 housing and $8685 in 1940-59 housing (in 2005 dollars). Annual energy savings are $130-486 per housing unit, with or without young resident children, with an associated increase in housing market value of $5900-14,300 per housing unit, depending on home size and number of windows replaced. Net benefits are $4490-5,629 for each housing unit built before 1940, and $491-1629 for each unit built from 1940-1959, depending on home size and number of windows replaced. Lead-safe window replacement in all pre-1960 US housing would yield net benefits of at least $67 billion, which does not include many other benefits. These other benefits, which are shown in this paper, include avoided Attention Deficit Hyperactivity Disorder, other medical costs of childhood lead exposure, avoided special education, and reduced crime and juvenile delinquency in later life. In addition, such a window replacement effort would reduce peak demand for electricity, carbon emissions from power plants, and associated long-term costs of climate change.

A COTS-Based Replacement Strategy for Aging Avionics Computers

DTIC Science & Technology

2001-12-01

Communication Control Unit. A COTS-Based Replacement Strategy for Aging Avionics Computers COTS Microprocessor Real Time Operating System New Native Code...Native Code Objec ts Native Code Thread Real - Time Operating System Legacy Function x Virtual Component Environment Context Switch Thunk Add-in Replace

77 FR 16430 - Airworthiness Directives; Airbus Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-21

... opposite the line replaceable unit racking. This AD requires replacing a certain aluminum high pressure... proposed to require replacing a certain aluminum high pressure pipe with a new corrosion resistant... comply with paragraph (1) of this [EASA] AD, unless, inadvertently, the high pressure pipe P/N...

Approximating the stress field within the unit cell of a fabric reinforced composite using replacement elements

NASA Technical Reports Server (NTRS)

Foye, R. L.

1993-01-01

This report concerns the prediction of the elastic moduli and the internal stresses within the unit cell of a fabric reinforced composite. In the proposed analysis no restrictions or assumptions are necessary concerning yarn or tow cross-sectional shapes or paths through the unit cell but the unit cell itself must be a right hexagonal parallelepiped. All the unit cell dimensions are assumed to be small with respect to the thickness of the composite structure that it models. The finite element analysis of a unit cell is usually complicated by the mesh generation problems and the non-standard, adjacent-cell boundary conditions. This analysis avoids these problems through the use of preprogrammed boundary conditions and replacement materials (or elements). With replacement elements it is not necessary to match all the constitutional material interfaces with finite element boundaries. Simple brick-shaped elements can be used to model the unit cell structure. The analysis predicts the elastic constants and the average stresses within each constituent material of each brick element. The application and results of this analysis are demonstrated through several example problems which include a number of composite microstructures.

Electronic-type vacuum gauges with replaceable elements

DOEpatents

Edwards, Jr., David

1984-01-01

In electronic devices for measuring pressures in vacuum systems, the metal elements which undergo thermal deterioration are made readily replaceable by making them parts of a simple plug-in unit. Thus, in ionization gauges, the filament and grid or electron collector are mounted on the novel plug-in unit. In thermocouple pressure gauges, the heater and attached thermocouple are mounted on the plug-in unit. Plug-in units have been designed to function, alternatively, as ionization gauge and as thermocouple gauge, thus providing new gauges capable of measuring broader pressure ranges than is possible with either an ionization gauge or a thermocouple gauge.

Mobile dental operations: capital budgeting and long-term viability.

PubMed

Arevalo, Oscar; Chattopadhyay, Amit; Lester, Harold; Skelton, Judy

2010-01-01

The University of Kentucky College of Dentistry (UKCD) runs a large mobile dental operation. Economic conditions dictate that as the mobile units age it will be harder to find donors willing or able to provide the financial resources for asset replacement. In order to maintain current levels of access for the underserved, consideration of replacement is paramount. A financial analysis for a new mobile unit was conducted to determine self-sustainability, return on investment (ROI), and feasibility of generating a cash reserve for its replacement in 12 years. Information on clinical income, operational and replacement costs, and capital costs was collected. A capital budgeting analysis (CBA) was conducted using the Net Present Value (NPV) methodology in four different scenarios. Depreciation funding was calculated by transferring funds from cash inflows and reinvested to offset depreciation at fixed compound interest. A positive ROI was obtained for two scenarios. He depreciation fund did not generate a cash reserve sufficient to replace the mobile unit. Mobile dental programs can play a vital role in providing access to care to underserved populations and ensuring their mission requires long-term planning. Careful financial viability and CBA based on sound assumptions are excellent decision-making tools.

Electronic-type vacuum gauges with replaceable elements

DOEpatents

Edwards, D. Jr.

1984-09-18

In electronic devices for measuring pressures in vacuum systems, the metal elements which undergo thermal deterioration are made readily replaceable by making them parts of a simple plug-in unit. Thus, in ionization gauges, the filament and grid or electron collector are mounted on the novel plug-in unit. In thermocouple pressure gauges, the heater and attached thermocouple are mounted on the plug-in unit. Plug-in units have been designed to function, alternatively, as ionization gauge and as thermocouple gauge, thus providing new gauges capable of measuring broader pressure ranges than is possible with either an ionization gauge or a thermocouple gauge. 5 figs.

Oligosaccharide Mimetics

NASA Astrophysics Data System (ADS)

Wessel, Hans Peter; Lucas, Susana Dias

The important roles of oligosaccharides in physiological and pathophysiological processes have spurred the development of mimetics. Oligosaccharide mimetics discussed in this chapter may possess a linker of two or more atoms such as amide or urea groups that may lead to isosteric linkage replacements but mostly do not. Larger groups that replace a full sugar unit we refer to as spacers and have grouped molecules with flexible acyclic spacers and more rigid cyclic spacers . The employment of pharmacophore models has led to oligosaccharide mimetics with only one sugar unit or finally without any saccharide unit as exemplified in mimotopes.

The management of failed ankle replacement.

PubMed

Kotnis, R; Pasapula, C; Anwar, F; Cooke, P H; Sharp, R J

2006-08-01

Advances in the design of the components for total ankle replacement have led to a resurgence of interest in this procedure. Between January 1999 and December 2004, 16 patients with a failed total ankle replacement were referred to our unit. In the presence of infection, a two-stage salvage procedure was planned. The first involved the removal of the components and the insertion of a cement spacer. Definitive treatment options included hindfoot fusion with a circular frame or amputation. When there was no infection, a one-stage salvage procedure was planned. Options included hindfoot fusion with an intramedullary nail or revision total ankle replacement. When there was suspicion of infection, a percutaneous biopsy was performed. The patients were followed up for a minimum of 12 months. Of the 16 patients, 14 had aseptic loosening, five of whom underwent a revision total ankle replacement and nine a hindfoot fusion. Of the two with infection, one underwent fusion and the other a below-knee amputation. There were no cases of wound breakdown, nonunion or malunion. Management of the failed total ankle replacement should be performed by experienced surgeons and ideally in units where multidisciplinary support is available. Currently, a hindfoot fusion appears to be preferable to a revision total ankle replacement.

Olkiluoto 1 and 2 - Plant efficiency improvement and lifetime extension-project (PELE) implemented during outages 2010 and 2011

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kosonen, M.; Hakola, M.

2012-07-01

Teollisuuden Voima Oyj (TVO) is a non-listed public company founded in 1969 to produce electricity for its stakeholders. TVO is the operator of the Olkiluoto nuclear power plant. TVO follows the principle of continuous improvement in the operation and maintenance of the Olkiluoto plant units. The PELE project (Plant Efficiency Improvement and Lifetime Extension), mainly completed during the annual outages in 2010 and 2011, and forms one part of the systematic development of Olkiluoto units. TVO maintains a long-term development program that aims at systematically modernizing the plant unit systems and equipment based on the latest technology. According to themore » program, the Olkiluoto 1 and Olkiluoto 2 plant units are constantly renovated with the intention of keeping them safe and reliable, The aim of the modernization projects is to improve the safety, reliability, and performance of the plant units. PELE project at Olkiluoto 1 was done in 2010 and at Olkiluoto 2 in 2011. The outage length of Olkiluoto 1 was 26 d 12 h 4 min and Olkiluoto 2 outage length was 28 d 23 h 46 min. (Normal service-outage is about 14 days including refueling and refueling-outage length is about seven days. See figure 1) The PELE project consisted of several single projects collected into one for coordinated project management. Some of the main projects were as follows: - Low pressure turbines: rotor, stator vane, casing and turbine instrumentation replacement. - Replacement of Condenser Cooling Water (later called seawater pumps) pumps - Replacement of inner isolation valves on the main steam lines. - Generator and the generator cooling system replacement. - Low voltage switchgear replacement. This project will continue during future outages. PELE was a success. 100 TVO employees and 1500 subcontractor employees participated in the project. The execution of the PELE projects went extremely well during the outages. The replacement of the low pressure turbines and seawater pumps improved the efficiency of the plant units, and a power increase of nearly 20 MW was achieved at both plant units. PELE wonderfully manifests one of the strategic goals of our company; developing the competence of our in-house personnel by working in projects. (authors)« less

Developing conjugated polymers with high electron affinity by replacing a C-C unit with a B←N unit.

PubMed

Dou, Chuandong; Ding, Zicheng; Zhang, Zijian; Xie, Zhiyuan; Liu, Jun; Wang, Lixiang

2015-03-16

The key parameters of conjugated polymers are lowest unoccupied molecular orbital (LUMO) and highest occupied molecular orbital (HOMO) energy levels. Few approaches can simultaneously lower LUMO and HOMO energy levels of conjugated polymers to a large extent (>0.5 eV). Disclosed herein is a novel strategy to decrease both LUMO and HOMO energy levels of conjugated polymers by about 0.6 eV through replacement of a C-C unit by a B←N unit. The replacement makes the resulting polymer transform from an electron donor into an electron acceptor, and is proven by fluorescence quenching experiments and the photovoltaic response. This work not only provides an effective approach to tune the LUMO/HOMO energy levels of conjugated polymers, but also uses organic boron chemistry as a new toolbox to develop conjugated polymers with high electron affinity for polymer optoelectronic devices. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

78 FR 8821 - Abandoned Mine Land Reclamation Program; Limited Liability for Noncoal Reclamation by Certified...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-06

... balance replacement funds and certified in lieu funds--paid from the general funds of the United States Treasury and not subject to annual appropriations. Prior balance replacement funds are authorized by...(h)(1) and (h)(2) of SMCRA (prior balance replacement funding and certified in lieu funding...

Design and operation experience of 230 MWe CFB boilers at Turow power plant in Poland

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nowak, W.; Bis, Z.; Laskawiec, J.

The Power Station Turow is located in Bogatynia, Poland, and has operated 10 pulverized coal units each of 200 MW. The plant provided 2000 MW at the lowest cost per kWh in Poland. The Turow units have approached and in some cases already gone beyond their 25--30 year's design life. To meet Poland's new environmental standards, which are now compatible with the EU, Turow decided to replace and upgrade six units (No. 1 to 6) from 200 MW to 230 MW units and remove one unit No. 7. Units No. 8, 9 and 10 were equipped with dry sorbent desulfurizationmore » technology. Units No. 1 and 2 have been replaced with new clean coal circulating fluidized bed technology. The Power Station Turow with six CFB units is to be the largest in the world power station based on fluidized bed technology.« less

Usage of Bone Replacement Grafts in Periodontics and Oral Implantology and Their Current Levels of Clinical Evidence - A Systematic Assessment.

PubMed

Salem, Daliah; Natto, Zuhair; Elangovan, Satheesh; Karimbux, Nadeem

2016-08-01

The aim of this review is to evaluate the levels of clinical evidence for bone replacement grafts available in the United States for periodontics and oral implantology purposes. A search was performed using PubMed, the Cochrane Library, and Google Scholar for articles relating to the use of bone replacement grafts in implant and/or periodontics by two independent reviewers. Articles unrelated to the topic, not involving patients, not including abstracts, or in languages other than English were excluded. Selected articles were graded according to "levels of evidence" based on guidelines originally introduced by Wright et al. (2003). There was limited published peer-reviewed clinical literature available regarding US commercially available bone replacement grafts in periodontics and oral implantology. Of 144 bone replacement grafts available in the United States according to Avila-Ortiz et al. (2013), only 52 met the inclusion criteria. The majority of materials used were allografts (26 of 93 available in the United States), followed by alloplasts (15 of 30) and xenografts (11 of 21). Dental providers should be aware of the limited evidence that qualified for a strong rating supporting the clinical efficacy of these materials for periodontics and oral implantology purposes using the inclusion criteria selected in this study.

Functional Tooth Regeneration Using a Bioengineered Tooth Unit as a Mature Organ Replacement Regenerative Therapy

PubMed Central

Imamura, Aya; Ogawa, Miho; Yasukawa, Masato; Yamazaki, Hiromichi; Morita, Ritsuko; Ikeda, Etsuko; Nakao, Kazuhisa; Takano-Yamamoto, Teruko; Kasugai, Shohei; Saito, Masahiro; Tsuji, Takashi

2011-01-01

Donor organ transplantation is currently an essential therapeutic approach to the replacement of a dysfunctional organ as a result of disease, injury or aging in vivo. Recent progress in the area of regenerative therapy has the potential to lead to bioengineered mature organ replacement in the future. In this proof of concept study, we here report a further development in this regard in which a bioengineered tooth unit comprising mature tooth, periodontal ligament and alveolar bone, was successfully transplanted into a properly-sized bony hole in the alveolar bone through bone integration by recipient bone remodeling in a murine transplantation model system. The bioengineered tooth unit restored enough the alveolar bone in a vertical direction into an extensive bone defect of murine lower jaw. Engrafted bioengineered tooth displayed physiological tooth functions such as mastication, periodontal ligament function for bone remodeling and responsiveness to noxious stimulations. This study thus represents a substantial advance and demonstrates the real potential for bioengineered mature organ replacement as a next generation regenerative therapy. PMID:21765896

Rehabilitation of a 410-MW utility boiler at Costa Sur, Puerto Rico

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rosado, R.; Salmeron, M.

1995-12-31

To increase unit reliability and availability and to meet the current and future electric power demands in Puerto Rico, the Puerto Rico Electric Power Authority (PREPA) recently performed a scheduled outage rehabilitation of Costa Sur Power Station Unit 5. This major rehabilitation of a 23-year-old, 410 MW, oil-fired boiler was accompanied by the upgrading of the low-pressure turbine with new rotors. The boiler rehabilitation included the replacement of all waterwall floor panels from just below the burner windbox, down to the lower drum. Temporary support was provided for the lower drum and its structural system during the panel replacement. Themore » steam drum internals were completely rehabilitated, with the installation of a new liner and cleaning and repair of other internals as required. The superheater and reheater desuperheater liners were also replaced. In addition, all major components of both the firing system and the air preheaters were replaced. The gas recirculation fan was rehabilitated, and its discharge duct was replaced.« less

Single Project Replaces District's Windows.

ERIC Educational Resources Information Center

American School and University, 1981

1981-01-01

The towns of Maplewood and South Orange (New Jersey) earmarked over $1 million, raised from a bond issue, to replace with thermal aluminum-framed units the 2400 worn out windows in eight 50-year-old schools. (Author)

Incidence and Patient Outcomes in Renal Replacement Therapy After Orthotopic Liver Transplant.

PubMed

Ayhan, Asude; Ersoy, Zeynep; Ulas, Aydin; Zeyneloglu, Pinar; Pirat, Arash; Haberal, Mehmet

2017-02-01

Our objective was to evaluate the incidence of renal replacement therapy after orthotopic liver transplant and to evaluate and analyze patient outcomes. We performed a retrospective analysis of 177 consecutive patients at a tertiary care unit who underwent orthotopic liver transplant between January 2010 and June 2016. Patients who were admitted to the intensive care unit after orthotopic liver transplant and who required renal replacement therapy were included. A total of 177 (79 adult, 98 pediatric) orthotopic liver transplants were performed during the study period. Of these, 35 patients (19%) required renal replacement therapy during the early posttransplantation period. After excluding 5 patients with previous chronic renal failure, 30 patients (17%; 20 adult [25% ], 10 pediatric [10% ]) with acute kidney injury required renal replacement therapy. The mean patient age was 31.1 ± 20.0 years, with a mean Model for End-stage Liver Disease score of 16.7 ± 12.3. Of the patients with acute kidney injury who underwent renal replacement therapy, in-hospital mortality was 23.3% (7 of 30 patients), and 40% remained on dialysis. No significant difference was seen in mortality between early versus delayed initiation of renal replacement therapy in patients with stage 3 acute kidney injury (P = .17). Of liver transplant recipients who present with acute kidney injury, 19% require renal replacement therapy, and in-hospital mortality is 20% in the early postoperative period.

International Space Station (ISS) Orbital Replaceable Unit (ORU) Wet Storage Risk Assessment

NASA Technical Reports Server (NTRS)

Squire, Michael D.; Rotter, Henry A.; Lee, Jason; Packham, Nigel; Brady, Timothy K.; Kelly, Robert; Ott, C. Mark

2014-01-01

The International Space Station (ISS) Program requested the NASA Engineering and Safety Center (NESC) to evaluate the risks posed by the practice of long-term wet storage of ISS Environmental Control and Life Support (ECLS) regeneration system orbital replacement units (ORUs). The ISS ECLS regeneration system removes water from urine and humidity condensate and converts it into potable water and oxygen. A total of 29 ORUs are in the ECLS system, each designed to be replaced by the ISS crew when necessary. The NESC assembled a team to review the ISS ECLS regeneration system and evaluate the potential for biofouling and corrosion. This document contains the outcome of the evaluation.

Evaluation of the impact of banking umbilical cord blood units with high cell dose for ethnically diverse patients.

PubMed

Stritesky, Gretta; Wadsworth, Kimberly; Duffy, Merry; Buck, Kelly; Dehn, Jason

2018-02-01

Umbilical cord blood units provide an important stem cell source for transplantation, particularly for patients of ethnic diversity who may not have suitably matched available, adult-unrelated donors. However, with the cost of cord blood unit acquisition from public banks significantly higher than that for adult-unrelated donors, attention is focused on decreasing cost yet still providing cord blood units to patients in need. Historical practices of banking units with low total nucleated cell counts, including units with approximately 90 × 10 7 total nucleated cells, indicates that most banked cord blood units have much lower total nucleated cell counts than are required for transplant. The objective of this study was to determine the impact on the ability to identify suitable cord blood units for transplantation if the minimum total nucleated cell count for banking were increased from 90 × 10 7 to 124 or 149 × 10 7 . We analyzed ethnically diverse patients (median age, 3 years) who underwent transplantation of a single cord blood unit in 2005 to 2016. A cord blood unit search was evaluated to identify units with equal or greater human leukocyte antigen matching and a greater total nucleated cell count than that of the transplanted cord blood unit (the replacement cord blood unit). If the minimum total nucleated cell count for banking increased to 124 or 149 × 10 7 , then from 75 to 80% of patients would still have at least 1 replacement cord blood unit in the current (2016) cord blood unit inventory. The best replacement cord blood units were often found among cords with the same ethnic background as the patient. The current data suggest that, if the minimum total nucleated cell count were increased for banking, then it would likely lead to an inventory of more desirable cord blood units while having minimal impact on the identification of suitable cord blood units for transplantation. © 2017 AABB.

77 FR 12448 - Airworthiness Directives; Pratt & Whitney Division Turbofan Engines

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-01

... Delta Airlines, Inc. requested that we specify replacing affected FMUs with FMU P/N 53U044, or later FAA... actual cost of the AD; not other costs. We did not change the AD. Request To Replace FMUs On-Wing United Parcel Service Co. requested that we include in the AD the option to perform on-wing replacements of...

Energy content in dried leaf litter of some oaks and mixed mesophytic species that replace oaks

Treesearch

Aaron D. Stottlemeyer; G. Geoff Wang; Patrick H. Brose; Thomas A. Waldrop

2010-01-01

Mixed-mesophytic hardwood tree species are replacing upland oaks in vast areas of the Eastern United States deciduous forest. Some researchers have suggested that the leaf litter of mixed-mesophytic, oak replacement species renders forests less flammable where forest managers wish to restore a natural fire regime. We performed chemical analyses on dried leaf litter...

Prevalence of Total Hip and Knee Replacement in the United States.

PubMed

Maradit Kremers, Hilal; Larson, Dirk R; Crowson, Cynthia S; Kremers, Walter K; Washington, Raynard E; Steiner, Claudia A; Jiranek, William A; Berry, Daniel J

2015-09-02

Descriptive epidemiology of total joint replacement procedures is limited to annual procedure volumes (incidence). The prevalence of the growing number of individuals living with a total hip or total knee replacement is currently unknown. Our objective was to estimate the prevalence of total hip and total knee replacement in the United States. Prevalence was estimated using the counting method by combining historical incidence data from the National Hospital Discharge Survey and the Healthcare Cost and Utilization Project (HCUP) State Inpatient Databases from 1969 to 2010 with general population census and mortality counts. We accounted for relative differences in mortality rates between those who have had total hip or knee replacement and the general population. The 2010 prevalence of total hip and total knee replacement in the total U.S. population was 0.83% and 1.52%, respectively. Prevalence was higher among women than among men and increased with age, reaching 5.26% for total hip replacement and 10.38% for total knee replacement at eighty years. These estimates corresponded to 2.5 million individuals (1.4 million women and 1.1 million men) with total hip replacement and 4.7 million individuals (3.0 million women and 1.7 million men) with total knee replacement in 2010. Secular trends indicated a substantial rise in prevalence over time and a shift to younger ages. Around 7 million Americans are living with a hip or knee replacement, and consequently, in most cases, are mobile, despite advanced arthritis. These numbers underscore the substantial public health impact of total hip and knee arthroplasties. Copyright © 2015 by The Journal of Bone and Joint Surgery, Incorporated.

"Life without nuclear power": A nuclear plant retirement formulation model and guide based on economics. San Onofre Nuclear Generating Station case: Economic impacts and reliability considerations leading to plant retirement

NASA Astrophysics Data System (ADS)

Wasko, Frank

Traditionally, electric utilities have been slow to change and very bureaucratic in nature. This culture, in and of itself, has now contributed to a high percentage of United States electric utilities operating uneconomical nuclear plants (Crooks, 2014). The economic picture behind owning and operating United States nuclear plants is less than favorable for many reasons including rising fuel, capital and operating costs (EUCG, 2012). This doctoral dissertation is specifically focused on life without nuclear power. The purpose of this dissertation is to create a model and guide that will provide electric utilities who currently operate or will operate uneconomical nuclear plants the opportunity to economically assess whether or not their nuclear plant should be retired. This economic assessment and stakeholder analysis will provide local government, academia and communities the opportunity to understand how Southern California Edison (SCE) embraced system upgrade import and "voltage support" opportunities to replace "base load" generation from San Onofre Nuclear Generating Station (SONGS) versus building new replacement generation facilities. This model and guide will help eliminate the need to build large replacement generation units as demonstrated in the SONGS case analysis. The application of The Nuclear Power Retirement Model and Guide will provide electric utilities with economic assessment parameters and an evaluation assessment progression needed to better evaluate when an uneconomical nuclear plant should be retired. It will provide electric utilities the opportunity to utilize sound policy, planning and development skill sets when making this difficult decision. There are currently 62 nuclear power plants (with 100 nuclear reactors) operating in the United States (EIA, 2014). From this group, 38 are at risk of early retirement based on the work of Cooper (2013). As demonstrated in my model, 35 of the 38 nuclear power plants qualify to move to the economic assessment review and then on to the stakeholder cost benefit analysis (if model qualifications are met) leading to a final plant retirement decision. This application via the model and guide, in turn, will lead electric utilities to explore system upgrade import opportunities and mitigation measures versus building new replacement generation facilities. United States nuclear reactors are licensed for 40 years with a 20 year extension available prior to the expiration date (EIA, 2013). Since late 2012, electric power companies have announced the early retirement of four uneconomical nuclear power plants while other studies have indicated that as many as 70 percent of United States nuclear power plants are potentially at risk for early retirement (Crooks, 2014 and Cooper, 2013). A high percentage of these aforementioned nuclear plants have operating licenses that will not expire until 2030 and beyond. Thus, for the most part, replacement power contingency planning has not been initiated for these plants or is still in preliminary stages. The recent nuclear plant retirements are the first since 1998 (EIA, 2013). Decisions to retire the plants involved concerns over maintenance and repair costs as well as declining profitability (EIA, 2013). In addition, the Energy Information Administration (2010-2012) released data that demonstrated that the worst 25 percent of United States nuclear plants are far more expensive to operate and generate electricity than new gas plants. It is equally important to understand and explain the economic and power replacement implications to both ratepayers and end-users. A SONGS case study analysis will review the economic, operational and political challenges that SCE faced leading to the retirement decision of SONGS. As preface to the case study, replacement steam generators (RSGs) were installed in Unit 2 in 2009 and in Unit 3 in 2010. In January 2012, while Unit 2 was down for routine maintenance, a small leak was discovered inside a steam generator in Unit 3. Because of the situation, both units remained shut down to evaluate the cause of the leakage and to make repairs. SCE submitted plans to the Nuclear Regulatory Commission (NRC) to re-start Unit 2 at reduced power. However, concerns over the length of the review process and the high costs associated with steam generator repairs led SCE to retire both reactors (SCE SONGS Fact Sheets, 2012-2013). Finally, collaborative resource power replacement planning is needed more than ever as nuclear facilities in the United States are now being retired for economic related reasons (Crooks, 2014). This collaborative power replacement process and implementation must encompass all relevant stakeholders including state grid operators, ratepayers, shareholders and the electric utility company.

Selection of Environmentally Friendly Solvents for the Extravehicular Mobility Unit Secondary Oxygen Pack Cold Trap Testing

NASA Technical Reports Server (NTRS)

Steele, John; Chullen, Cinda; Morenz, Jesse; Stephenson, Curtis

2010-01-01

Freon-113(TradeMark) has been used as a chemistry lab sampling solvent at NASA/JSC for EMU (extravehicular Mobility Unit) SOP (Secondary Oxygen Pack) oxygen testing Cold Traps utilized at the USA (United Space Alliance) Houston facility. Similar testing has occurred at the HSWL (Hamilton Sundstrand Windsor Locks) facility. A NASA Executive Order bans the procurement of all ODS (ozone depleting substances), including Freon-113 by the end of 2009. In order to comply with NASA direction, HSWL began evaluating viable solvents to replace Freon-113 . The study and testing effort to find Freon-113 replacements used for Cold Trap sampling is the subject of this paper. Test results have shown HFE-7100 (a 3M fluorinated ether) to be an adequate replacement for Freon-113 as a solvent to remove and measure the non-volatile residue collected in a Cold Trap during oxygen testing. Furthermore, S-316 (a Horiba Instruments Inc. high molecular weight, non-ODS chlorofluorocarbon) was found to be an adequate replacement for Freon-113 as a solvent to reconstitute non-volatile residue removed from a Cold Trap during oxygen testing for subsequent HC (hydrocarbon) analysis via FTIR (Fourier Transform Infrared Spectroscopy).

Spline screw payload fastening system

NASA Technical Reports Server (NTRS)

Vranish, John M. (Inventor)

1993-01-01

A system for coupling an orbital replacement unit (ORU) to a space station structure via the actions of a robot and/or astronaut is described. This system provides mechanical and electrical connections both between the ORU and the space station structure and between the ORU and the ORU and the robot/astronaut hand tool. Alignment and timing features ensure safe, sure handling and precision coupling. This includes a first female type spline connector selectively located on the space station structure, a male type spline connector positioned on the orbital replacement unit so as to mate with and connect to the first female type spline connector, and a second female type spline connector located on the orbital replacement unit. A compliant drive rod interconnects the second female type spline connector and the male type spline connector. A robotic special end effector is used for mating with and driving the second female type spline connector. Also included are alignment tabs exteriorally located on the orbital replacement unit for berthing with the space station structure. The first and second female type spline connectors each include a threaded bolt member having a captured nut member located thereon which can translate up and down the bolt but are constrained from rotation thereabout, the nut member having a mounting surface with at least one first type electrical connector located on the mounting surface for translating with the nut member. At least one complementary second type electrical connector on the orbital replacement unit mates with at least one first type electrical connector on the mounting surface of the nut member. When the driver on the robotic end effector mates with the second female type spline connector and rotates, the male type spline connector and the first female type spline connector lock together, the driver and the second female type spline connector lock together, and the nut members translate up the threaded bolt members carrying the first type electrical connector up to the complementary second type connector for interconnection therewith.

New Method for Updating Mean Time Between Failure for ISS Orbital Replaceable Units Consultation Report

NASA Technical Reports Server (NTRS)

Parsons, Vickie S.

2009-01-01

A request to conduct a peer review of the International Space Station (ISS) proposal to use Bayesian methodology for updating Mean Time Between Failure (MTBF) for ISS Orbital Replaceable Units (ORU) was submitted to the NASA Engineering and Safety Center (NESC) on September 20, 2005. The results were requested by October 20, 2005 in order to be available during the process of reworking the current ISS flight manifest. The results are included in this report.

Description of the attitude control, guidance and navigation space replaceable units for automated space servicing of selected NASA missions

NASA Technical Reports Server (NTRS)

Chobotov, V. A.

1974-01-01

Control elements such as sensors, momentum exchange devices, and thrusters are described which can be used to define space replaceable units (SRU), in accordance with attitude control, guidance, and navigation performance requirements selected for NASA space serviceable mission spacecraft. A number of SRU's are developed, and their reliability block diagrams are presented. An SRU assignment is given in order to define a set of feasible space serviceable spacecraft for the missions of interest.

44 CFR 62.20 - Claims appeals.

Code of Federal Regulations, 2010 CFR

2010-10-01

... (includes contractors' estimates), detailing unit cost and quantities for the items needing repair or replacement; replacement cost proofs of loss; Preliminary Report; Final Report; detailed damaged personal... wind policies and any claim information submitted to the other companies; Waiver, Letter of Map...

44 CFR 62.20 - Claims appeals.

Code of Federal Regulations, 2011 CFR

2011-10-01

... (includes contractors' estimates), detailing unit cost and quantities for the items needing repair or replacement; replacement cost proofs of loss; Preliminary Report; Final Report; detailed damaged personal... wind policies and any claim information submitted to the other companies; Waiver, Letter of Map...

OGS Maintenance

NASA Image and Video Library

2010-07-21

ISS024-E-009246 (21 July 2010) --- NASA astronaut Tracy Caldwell Dyson, Expedition 24 flight engineer, is pictured during troubleshooting operations of the Oxygen Generator System (OGS) hardware and replacement of an H2 (hydrogen) Dome Orbit Replaceable Unit (ORU) in the Destiny laboratory of the International Space Station.

Replacement of fluid-filter elements without interruption of flow

NASA Technical Reports Server (NTRS)

Kotler, R. A.; Ward, J. B.

1969-01-01

Gatling-type filter assembly, preloaded with several filter elements enables filter replacement without breaking into the operative fluid system. When the filter element becomes contaminated, a unit inner subassembly is rotated 60 degrees to position a clean filter in the line.

Computer-generated scenes depicting the HST capture and EVA repair mission

NASA Image and Video Library

1993-11-12

Computer generated scenes depicting the Hubble Space Telescope capture and a sequence of planned events on the planned extravehicular activity (EVA). Scenes include the Remote Manipulator System (RMS) arm assisting two astronauts changing out the Wide Field/Planetary Camera (WF/PC) (48699); RMS arm assisting in the temporary mating of the orbiting telescope to the flight support system in Endeavour's cargo bay (48700); Endeavour's RMS arm assisting in the "capture" of the orbiting telescope (48701); Two astronauts changing out the telescope's coprocessor (48702); RMS arm assistign two astronauts replacing one of the telescope's electronic control units (48703); RMS assisting two astronauts replacing the fuse plugs on the telescope's Power Distribution Unit (PDU) (48704); The telescope's High Resolution Spectrograph (HRS) kit is depicted in this scene (48705); Two astronauts during the removal of the high speed photometer and the installation of the COSTAR instrument (48706); Two astronauts, standing on the RMS, during installation of one of the Magnetic Sensing System (MSS) (48707); High angle view of the orbiting Space Shuttle Endeavour with its cargo bay doors open, revealing the bay's pre-capture configuration. Seen are, from the left, the Solar Array Carrier, the ORU Carrier and the flight support system (48708); Two astronauts performing the replacement of HST's Rate Sensor Units (RSU) (48709); The RMS arm assisting two astronauts with the replacement of the telescope's solar array panels (48710); Two astronauts replacing the telescope's Solar Array Drive Electronics (SADE) (48711).

Replacement solvents for use in chemical synthesis

DOEpatents

Molnar, Linda K.; Hatton, T. Alan; Buchwald, Stephen L.

2001-05-15

Replacement solvents for use in chemical synthesis include polymer-immobilized solvents having a flexible polymer backbone and a plurality of pendant groups attached onto the polymer backbone, the pendant groups comprising a flexible linking unit bound to the polymer backbone and to a terminal solvating moiety. The polymer-immobilized solvent may be dissolved in a benign medium. Replacement solvents for chemical reactions for which tetrahydrofuran or diethyl may be a solvent include substituted tetrahydrofurfuryl ethers and substituted tetrahydro-3-furan ethers. The replacement solvents may be readily recovered from the reaction train using conventional methods.

[Cost-benefit analysis of the implementation of automated drug-dispensing systems in Critical Care and Emergency Units].

PubMed

Poveda Andrés, J L; García Gómez, C; Hernández Sansalvador, M; Valladolid Walsh, A

2003-01-01

To determine monetary impact when traditional drug floor stocks are replaced by Automated Drug Dispensing Systems (ADDS) in the Medical Intensive Care Unit, Surgical Intensive Care Unit and the Emergency Room. We analysed four different flows considered to be determinant when implementing ADDS in a hospital environment: capital investment, staff costs, inventory costs and costs related to drug use policies. Costs were estimated by calculation of the current net value. Its analysis shows that those expenses derived from initial investment are compensated by the three remaining flows, with costs related to drug use policies showing the most substantial savings. Five years after initial investment, global cash-flows have been estimated at 300.525 euros. Replacement of traditional floor stocks by ADDS in the Medical Intensive Care Unit, Surgery Intensive Care Unit and the Emergency Room produces a positive benefit/cost ratio (1.95).

Feasibility of flywheel energy storage systems for applications in future space missions

NASA Technical Reports Server (NTRS)

Santo, G. Espiritu; Gill, S. P.; Kotas, J. F.; Paschall, R.

1995-01-01

The objective of this study was to examine the overall feasibility of deploying electromechanical flywheel systems in space used for excess energy storage. Results of previous Rocketdyne studies have shown that the flywheel concept has a number of advantages over the NiH2 battery, including higher specific energy, longer life and high roundtrip efficiency. Based on this prior work, this current study was broken into four subtasks. The first subtask investigated the feasibility of replacing the NiH2 battery orbital replacement unit (ORU) on the international space station (ISSA) with a flywheel ORU. In addition, a conceptual design of a generic flywheel demonstrator experiment implemented on the ISSA was completed. An assessment of the life cycle cost benefits of replacing the station battery energy storage ORU's with flywheel ORU's was performed. A fourth task generated a top-level development plan for critical flywheel technologies, the flywheel demonstrator experiments and its evolution into the production unit flywheel replacement ORU.

77 FR 55159 - Airworthiness Directives; The Boeing Company Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-07

... oxygen mask stowage box units; and replacement of the crew oxygen mask stowage box unit with a new crew oxygen mask stowage unit, if necessary. That NPRM was prompted by reports indicating that certain crew oxygen mask stowage box units were possibly delivered with a burr in the inlet fitting. The burr might...

Acute Respiratory Failure Induced by Magnesium Replacement in a 62-Year-Old Woman with Myasthenia Gravis.

PubMed

Singh, Paramveer; Idowu, Olakunle; Malik, Imrana; Nates, Joseph L

2015-10-01

Magnesium is known to act at the neuromuscular junction by inhibiting the presynaptic release of acetylcholine and desensitizing the postsynaptic membrane. Because of these effects, magnesium has been postulated to potentiate neuromuscular weakness. We describe the case of a 62-year-old woman with myasthenia gravis and a metastatic thymoma who was admitted to our intensive care unit for management of a myasthenic crisis. The patient's neuromuscular weakness worsened in association with standard intravenous magnesium replacement, and the exacerbated respiratory failure necessitated intubation, mechanical ventilation, and an extended stay in the intensive care unit. The effect of magnesium replacement on myasthenia gravis patients has not been well documented, and we present this case to increase awareness and stimulate research. In addition, we discuss the relevant medical literature.

KSC-08pd2084

NASA Image and Video Library

2008-07-18

CAPE CANAVERAL, Fla. – In the high bay of the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, the Orbital Replacement Unit Carrier, for the Hubble Space Telescope is unwrapped and awaits final processing for launch. The Orbital Replacement Unit Carrier, or ORUC, is one of four carriers supporting hardware for space shuttle Atlantis' STS-125 mission to service the telescope. The Super Lightweight Interchangeable Carrier, or SLIC, and the Flight Support System, or FSS, have also arrived at Kennedy. The Multi-Use Lightweight Equipment carrier will be delivered in late July. The carriers will be prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the Hubble servicing mission, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

75 FR 67637 - Airworthiness Directives; The Boeing Company Model 737-700, -700C, -800, and -900ER Series...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-03

... numbers of the crew oxygen mask stowage box units; and replacement of the crew oxygen mask stowage box unit with a new crew oxygen mask stowage unit, if necessary. This proposed AD results [[Page 67638

76 FR 5144 - Notice of Intent To Prepare an Environmental Impact Statement for U.S. Navy F-35C West Coast...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-28

...) aircraft on the West Coast of the United States. Under this proposal, a total of seven active-duty F/A-18C... one-for-one replacement. The aging FA-18C Hornet aircraft are expected to be replaced with F-35C..., Southwest; 619-532-2799. SUPPLEMENTARY INFORMATION: As a replacement for the Navy's aging F/A- 18C Hornet...

Development of a Tissue Engineered Scaffold for Meniscus Replacement

DTIC Science & Technology

2008-12-01

include loss of manpower, rehabilitation costs, waste of training time/ money , cost to retrain members as replacements, hospitalization costs, disability...injuries in the United States Armed Forces. Mil Med, 1999. 164(8 Suppl): p. 633 pages. Lauder , T.D., et al., Sports and physical training injury

FINDING SOLVENT REPLACEMENTS TO REDUCE THE POTENTIAL ENVIRONMENTAL IMPACT OF INDUSTRIAL WASTES

EPA Science Inventory

The United States Environmental Protection Agency has developed a solvent substitution software tool PARIS II (Program for Assisting the Replacement of Industrial Solvents, version 2.0). The purpose of this tool is to find less toxic solvents or solvent mixtures which may functi...

Optical Sensor of Thermal Gas Flow Based on Fiber Bragg Grating.

PubMed

Jiang, Xu; Wang, Keda; Li, Junqing; Zhan, Hui; Song, Zhenan; Che, Guohang; Lyu, Guohui

2017-02-15

This paper aims at solving the problem of explosion proof in measurement of thermal gas flow using electronic sensor by presenting a new type of flow sensor by optical fiber heating. A measuring unit based on fiber Bragg grating (FBG) for fluid temperature and a unit for heat dissipation are designed to replace the traditional electronic sensors. The light in C band from the amplified spontaneous emission (ASE) light source is split, with one part used to heat the absorbing coating and the other part used in the signal processing unit. In the heating unit, an absorbing coating is introduced to replace the traditional resistance heating module to minimize the risk of explosion. The measurement results demonstrate a fine consistency between the flow and temperature difference in simulation. The method to enhance the measurement resolution of flow is also discussed.

ISS EPS Orbital Replacement Unit Block Diagrams

NASA Technical Reports Server (NTRS)

Schmitz, Gregory V.

2001-01-01

The attached documents are being provided to Switching Power Magazine for information purposes. This magazine is writing a feature article on the International Space Station Electrical Power System, focusing on the switching power processors. These units include the DC-DC Converter Unit (DDCU), the Bi-directional Charge/Discharge Unit (BCDU), and the Sequential Shunt Unit (SSU). These diagrams are high-level schematics/block diagrams depicting the overall functionality of each unit.

37 CFR 1.805 - Replacement or supplement of deposit.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Replacement or supplement of deposit. 1.805 Section 1.805 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES Biotechnology Invention Disclosures Deposit...

37 CFR 1.805 - Replacement or supplement of deposit.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Replacement or supplement of deposit. 1.805 Section 1.805 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES Biotechnology Invention Disclosures Deposit...

Potential nutritional and economic effects of replacing juice with fruit in the diets of children in the United States.

PubMed

Monsivais, Pablo; Rehm, Colin D

2012-05-01

To estimate the nutritional and economic effects of substituting whole fruit for juice in the diets of children in the United States. Secondary analyses using the 2001-2004 National Health and Nutrition Examination Survey and a national food prices database. Energy intakes, nutrient intakes, and diet costs were estimated before and after fruit juices were completely replaced with fruit in 3 models that emphasized fruits that were fresh, inexpensive, and widely consumed and in a fourth model that partially replaced juice with fruit, capping juice at recommended levels. A nationwide, representative sample of children in the United States. A total of 7023 children aged 3 to 18 years. Systematic complete or partial replacement of juice with fruit. Difference in energy intakes, nutrient intakes, and diet costs between observed and modeled diets. For children who consumed juice, replacement of all juice servings with fresh, whole fruit led to a projected reduction in dietary energy of 233 kJ/d (-2.6% difference [95% CI, -5.1% to -0.1%]), an increase in fiber of 4.3 g/d (31.1% difference [95% CI, 26.4%-35.9%]), and an increase in diet cost of $0.54/d (13.3% difference [95% CI, 8.8%-17.8%]). Substitution of juice with fresh fruit has the potential to reduce energy intake and improve the adequacy of fiber intake in children's diets. This would likely increase costs for schools, childcare providers, and families. These cost effects could be minimized by selecting processed fruits, but fewer nutritional gains would be achieved.

The COHORT System - Is It Meeting the Army’s Needs

DTIC Science & Technology

1988-06-06

soldier replacement system. Analysis compar- ing the COHORT system to the older, and still widely used, Individual Replace- ment System (IRS) is provided...Trinn (OMMe) soldie I •, I IIsstem. Analysis c~mering the a- system to the older, arid still3 widely used, Individural Syasit em (M) is rovided. 7he...allegiances frequently...efficiencies in individual replacements take no account of unit cohesion in the tank company , cannon battery or the Infantry

Doing without dimensions

NASA Astrophysics Data System (ADS)

Spurgin, C. B.

1986-03-01

The author discusses the concept of dimensions of a physical quantity, and the relationship between derived units (expressed in terms of their base units) and the dimensions of the derived quantities. He calls for the replacement of 'dimensions' by base units in the GCE A-level syllabus and provides some recommendations to GCE examining boards.

KSC-08pd2077

NASA Image and Video Library

2008-07-18

CAPE CANAVERAL, Fla. – In the high bay of the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, a worker from NASA's Goddard Space Flight Center cuts away the protective wrapping from the Orbital Replacement Unit Carrier for the Hubble Space Telescope. The Orbital Replacement Unit Carrier, or ORUC, is one of four carriers supporting hardware for space shuttle Atlantis' STS-125 mission to service the telescope. The Super Lightweight Interchangeable Carrier, or SLIC, and the Flight Support System, or FSS, have also arrived at Kennedy. The Multi-Use Lightweight Equipment carrier will be delivered in late July. The carriers will be prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the Hubble servicing mission, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2081

NASA Image and Video Library

2008-07-18

CAPE CANAVERAL, Fla. – In the high bay of the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, a worker from NASA's Goddard Space Flight Center removes the protective wrapping from the Orbital Replacement Unit Carrier for the Hubble Space Telescope. The Orbital Replacement Unit Carrier, or ORUC, is one of four carriers supporting hardware for space shuttle Atlantis' STS-125 mission to service the telescope. The Super Lightweight Interchangeable Carrier, or SLIC, and the Flight Support System, or FSS, have also arrived at Kennedy. The Multi-Use Lightweight Equipment carrier will be delivered in late July. The carriers will be prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the Hubble servicing mission, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2075

NASA Image and Video Library

2008-07-18

CAPE CANAVERAL, Fla. – In the high bay of the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, workers from NASA's Goddard Space Flight Center begin to remove the protective wrapping from the Orbital Replacement Unit Carrier for the Hubble Space Telescope. The Orbital Replacement Unit Carrier, or ORUC, is one of four carriers supporting hardware for space shuttle Atlantis' STS-125 mission to service the telescope. The Super Lightweight Interchangeable Carrier, or SLIC, and the Flight Support System, or FSS, have also arrived at Kennedy. The Multi-Use Lightweight Equipment carrier will be delivered in late July. The carriers will be prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the Hubble servicing mission, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2074

NASA Image and Video Library

2008-07-18

CAPE CANAVERAL, Fla. – In the high bay of the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, the Orbital Replacement Unit Carrier for the Hubble Space Telescope is secured on a work platform by workers from NASA's Goddard Space Flight Center. The Orbital Replacement Unit Carrier, or ORUC, is one of four carriers supporting hardware for space shuttle Atlantis' STS-125 mission to service the telescope. The Super Lightweight Interchangeable Carrier, or SLIC, and the Flight Support System, or FSS, have also arrived at Kennedy. The Multi-Use Lightweight Equipment carrier will be delivered in late July. The carriers will be prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the Hubble servicing mission, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2076

NASA Image and Video Library

2008-07-18

CAPE CANAVERAL, Fla. – In the high bay of the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, a worker from NASA's Goddard Space Flight Center cuts away the protective wrapping from the Orbital Replacement Unit Carrier for the Hubble Space Telescope. The Orbital Replacement Unit Carrier, or ORUC, is one of four carriers supporting hardware for space shuttle Atlantis' STS-125 mission to service the telescope. The Super Lightweight Interchangeable Carrier, or SLIC, and the Flight Support System, or FSS, have also arrived at Kennedy. The Multi-Use Lightweight Equipment carrier will be delivered in late July. The carriers will be prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the Hubble servicing mission, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2070

NASA Image and Video Library

2008-07-18

CAPE CANAVERAL, Fla. – In the high bay of the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, the Orbital Replacement Unit Carrier for the Hubble Space Telescope is lifted from its transportation canister by workers from NASA's Goddard Space Flight Center. The Orbital Replacement Unit Carrier, or ORUC, is one of four carriers supporting hardware for space shuttle Atlantis' STS-125 mission to service the telescope. The Super Lightweight Interchangeable Carrier, or SLIC, and the Flight Support System, or FSS, have also arrived at Kennedy. The Multi-Use Lightweight Equipment carrier will be delivered in late July. The carriers will be prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the Hubble servicing mission, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2073

NASA Image and Video Library

2008-07-18

CAPE CANAVERAL, Fla. – In the high bay of the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, the Orbital Replacement Unit Carrier for the Hubble Space Telescope is positioned on a work platform by workers from NASA's Goddard Space Flight Center. The Orbital Replacement Unit Carrier, or ORUC, is one of four carriers supporting hardware for space shuttle Atlantis' STS-125 mission to service the telescope. The Super Lightweight Interchangeable Carrier, or SLIC, and the Flight Support System, or FSS, have also arrived at Kennedy. The Multi-Use Lightweight Equipment carrier will be delivered in late July. The carriers will be prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the Hubble servicing mission, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2080

NASA Image and Video Library

2008-07-18

CAPE CANAVERAL, Fla. – In the high bay of the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, a worker from NASA's Goddard Space Flight Center removes the protective wrapping from the Orbital Replacement Unit Carrier for the Hubble Space Telescope. The Orbital Replacement Unit Carrier, or ORUC, is one of four carriers supporting hardware for space shuttle Atlantis' STS-125 mission to service the telescope. The Super Lightweight Interchangeable Carrier, or SLIC, and the Flight Support System, or FSS, have also arrived at Kennedy. The Multi-Use Lightweight Equipment carrier will be delivered in late July. The carriers will be prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the Hubble servicing mission, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2078

NASA Image and Video Library

2008-07-18

CAPE CANAVERAL, Fla. – In the high bay of the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, a worker from NASA's Goddard Space Flight Center removes the protective wrapping from the Orbital Replacement Unit Carrier for the Hubble Space Telescope. The Orbital Replacement Unit Carrier, or ORUC, is one of four carriers supporting hardware for space shuttle Atlantis' STS-125 mission to service the telescope. The Super Lightweight Interchangeable Carrier, or SLIC, and the Flight Support System, or FSS, have also arrived at Kennedy. The Multi-Use Lightweight Equipment carrier will be delivered in late July. The carriers will be prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the Hubble servicing mission, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2079

NASA Image and Video Library

2008-07-18

CAPE CANAVERAL, Fla. – In the high bay of the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, a worker from NASA's Goddard Space Flight Center removes the protective wrapping from the Orbital Replacement Unit Carrier for the Hubble Space Telescope. The Orbital Replacement Unit Carrier, or ORUC, is one of four carriers supporting hardware for space shuttle Atlantis' STS-125 mission to service the telescope. The Super Lightweight Interchangeable Carrier, or SLIC, and the Flight Support System, or FSS, have also arrived at Kennedy. The Multi-Use Lightweight Equipment carrier will be delivered in late July. The carriers will be prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the Hubble servicing mission, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

Operations analysis (study 2.1): Payload designs for space servicing

NASA Technical Reports Server (NTRS)

Wolfe, R. R.

1974-01-01

Potential modes of operating in space in the space shuttle era are documented. The October 1973 NASA Mission Model provides a definition of various NASA and non-DOD automated payload configurations when employed in an expendable mode. The model also specifies a launch schedule for initial deployment of payloads as well as for subsequent replacements at periodic cycles. This model and its associated payload definitions serve as a foundation for the data presented in this report. The reference model has been revised to reflect automated space servicing of payloads as an operational concept instead of the existing expendable approach. The indication is that the bulk of a payload's subsystems and mission equipment require no support over the lifetime of the program. However, failure of a single unit could result in loss of the mission objectives. When space servicing is employed, the approach is to replace only that unit causing the anomaly. This concept affords an opportunity to standardize space replacable units, as well as to reduce the expense of logistics support, by allowing multiple servicing on any single upper stage/shuttle flight.

76 FR 20969 - City and Borough of Sitka, AK; Notice of Application Accepted for Filing, Ready for Environmental...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-14

... megawatt (MW) turbine-generator units near the existing powerhouse. Additionally, the Fish Valve Unit would be replaced with a new 1 MW turbine-generator unit and the 870 kilowatt Pulp Mill Feeder Unit would... new water intake in the reservoir 109 feet above the existing intake. The higher maximum reservoir...

Determining the value of the fine-structure constant from a current balance: Getting acquainted with some upcoming changes to the SI

NASA Astrophysics Data System (ADS)

Davis, Richard S.

2017-05-01

The revised International System of Units (SI), expected to be approved late in 2018, has implications for physics pedagogy. The ampere definition, which dates from 1948, will be replaced by a definition that fixes the numerical value of the elementary charge e in coulombs. The kilogram definition, which dates from 1889, will be replaced by a definition that fixes the numerical value of the Planck constant h in joule seconds. Existing SI equations will be completely unaffected. However, there will be a largely negligible, but nevertheless necessary, change to published numerical factors relating SI electrical units to their corresponding units in the Gaussian and other CGS systems of units. The implications of the revised SI for electrical metrology are neatly illustrated by considering the interpretation of results obtained from a current balance in the present SI and in the revised SI.

Environmentally Friendly Replacement of Mature 200 MW Coal-Fired Power Blocks with 2 Boilers Working on One 500 MW Class Steam Turbine Generator (2on1 Unit Concept)

NASA Astrophysics Data System (ADS)

Grzeszczak, Jan; Grela, Łukasz; Achter, Thomas

2017-12-01

The paper covers problems of the owners of a fleet of long-operated conventional power plants that are going to be decommissioned soon in result of failing to achieve new admissible emissions levels or exceeding pressure elements design lifetime. Energoprojekt-Katowice SA, Siemens AG and Rafako SA presents their joint concept of the solution which is a 2on1 concept - replacing two unit by two ultra-supercritical boilers feeding one turbine. Polish market has been taken as an example.

Degradation of Beta-Cloth Covering for a Battery Orbital Replacement Unit in Low Earth Orbit

NASA Technical Reports Server (NTRS)

Gaier, James R.; Baldwin, Sammantha; Folz, Angela D.; Waters, Deborah L.; Loos, Alyssa

2016-01-01

Samples from the B-cloth cover for a battery orbit replaceable unit from the International Space Station were characterized using optical and electron microscopy, UV-vis-NIR spectrophotometry, and x-ray energy dispersive spectroscopy. Results showed that in areas where the fabric was exposed to solar radiation the absorptance increased by as much as 20 percent, and the peak difference was in the ultraviolet, indicating that the increased absorptance may have been due to radiation. The emissivity of the material over a temperature range of 300 - 700 K was essentially unchanged.

Degradation of Beta Cloth Covering for a Battery Orbital Replacement Unit in Low Earth Orbit

NASA Technical Reports Server (NTRS)

Gaier, James R.; Waters, Deborah L.; Baldwin, Sammantha; Folz, Angela D.; Loos, Alyssa

2016-01-01

Samples from the beta cloth cover for a battery orbit replaceable unit from the International Space Station (ISS) were characterized using optical and electron microscopy, UV-vis-NIR spectrophotometry, and x-ray energy dispersive spectroscopy. Results showed that in areas where the fabric was exposed to solar radiation the absorptance increased by as much as 20 percent, and the peak difference was in the ultraviolet, indicating that the increased absorptance may have been due to radiation. The emissivity of the material over a temperature range of 300 to 700 K was essentially unchanged.

Improving the Estimates of International Space Station (ISS) Induced K-Factor Failure Rates for On-Orbit Replacement Unit (ORU) Supportability Analyses

NASA Technical Reports Server (NTRS)

Anderson, Leif F.; Harrington, Sean P.; Omeke, Ojei, II; Schwaab, Douglas G.

2009-01-01

This is a case study on revised estimates of induced failure for International Space Station (ISS) on-orbit replacement units (ORUs). We devise a heuristic to leverage operational experience data by aggregating ORU, associated function (vehicle sub -system), and vehicle effective' k-factors using actual failure experience. With this input, we determine a significant failure threshold and minimize the difference between the actual and predicted failure rates. We conclude with a discussion on both qualitative and quantitative improvements the heuristic methods and potential benefits to ISS supportability engineering analysis.

37 CFR 7.28 - Replacement of U.S. registration by registered extension of protection.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Replacement of U.S. registration by registered extension of protection. 7.28 Section 7.28 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE RULES OF PRACTICE IN FILINGS PURSUANT...

Estimation of Variance in the Case of Complex Samples.

ERIC Educational Resources Information Center

Groenewald, A. C.; Stoker, D. J.

In a complex sampling scheme it is desirable to select the primary sampling units (PSUs) without replacement to prevent duplications in the sample. Since the estimation of the sampling variances is more complicated when the PSUs are selected without replacement, L. Kish (1965) recommends that the variance be calculated using the formulas…

HEATING ATTIC AIR USING SOLAR THERMAL ENERGY FOR SPACE HEATING AND DRYING APPLICATIONS

EPA Science Inventory

This unit is expected to replace the conventional forms of drying and will be able to supplement space heating. Replacement of these current forms of drying and space heating will result in the reduction of energy consumption from this sector which will also lead to cost savin...

37 CFR 7.29 - Effect of replacement on U.S. registration.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Effect of replacement on U.S. registration. 7.29 Section 7.29 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE RULES OF PRACTICE IN FILINGS PURSUANT TO THE PROTOCOL RELATING TO THE MADRID AGREEMENT...

37 CFR 7.29 - Effect of replacement on U.S. registration.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Effect of replacement on U.S. registration. 7.29 Section 7.29 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE RULES OF PRACTICE IN FILINGS PURSUANT TO THE PROTOCOL RELATING TO THE MADRID AGREEMENT...

37 CFR 7.29 - Effect of replacement on U.S. registration.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 37 Patents, Trademarks, and Copyrights 1 2012-07-01 2012-07-01 false Effect of replacement on U.S. registration. 7.29 Section 7.29 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE RULES OF PRACTICE IN FILINGS PURSUANT TO THE PROTOCOL RELATING TO THE MADRID AGREEMENT...

37 CFR 7.29 - Effect of replacement on U.S. registration.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Effect of replacement on U.S. registration. 7.29 Section 7.29 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE RULES OF PRACTICE IN FILINGS PURSUANT TO THE PROTOCOL RELATING TO THE MADRID AGREEMENT...

37 CFR 7.29 - Effect of replacement on U.S. registration.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Effect of replacement on U.S. registration. 7.29 Section 7.29 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE RULES OF PRACTICE IN FILINGS PURSUANT TO THE PROTOCOL RELATING TO THE MADRID AGREEMENT...

46 CFR 56.01-1 - Scope (replaces 100.1).

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 2 2013-10-01 2013-10-01 false Scope (replaces 100.1). 56.01-1 Section 56.01-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PIPING SYSTEMS AND... operation of the vessel. (c) Piping for industrial systems on mobile offshore drilling units need not fully...

46 CFR 56.01-1 - Scope (replaces 100.1).

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Scope (replaces 100.1). 56.01-1 Section 56.01-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PIPING SYSTEMS AND... operation of the vessel. (c) Piping for industrial systems on mobile offshore drilling units need not fully...

46 CFR 56.01-1 - Scope (replaces 100.1).

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 2 2012-10-01 2012-10-01 false Scope (replaces 100.1). 56.01-1 Section 56.01-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PIPING SYSTEMS AND... operation of the vessel. (c) Piping for industrial systems on mobile offshore drilling units need not fully...

46 CFR 56.01-1 - Scope (replaces 100.1).

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 2 2011-10-01 2011-10-01 false Scope (replaces 100.1). 56.01-1 Section 56.01-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PIPING SYSTEMS AND... operation of the vessel. (c) Piping for industrial systems on mobile offshore drilling units need not fully...

46 CFR 56.01-1 - Scope (replaces 100.1).

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 2 2014-10-01 2014-10-01 false Scope (replaces 100.1). 56.01-1 Section 56.01-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PIPING SYSTEMS AND... operation of the vessel. (c) Piping for industrial systems on mobile offshore drilling units need not fully...

Development of an intelligent controller for power generators

NASA Astrophysics Data System (ADS)

Maxted, Clive; Waller, Winston

2005-01-01

This paper is a description of the development of an embedded controller for high power industrial diesel generators. The aim of the project was to replace the existing discrete logic design by an intelligent versatile and user configurable control system. A prototype embedded PC controlled system was developed, capable of fully replacing the existing system, with a colour TFT display and keypad. Features include fully automatic generator control as before with status and alarm display and monitoring of engine parameters, along with data logging, remote communications and a means of analysing data. The unit was tested on the bench and on diesel generators for the core controlling functionality to prove compliance with the specifications. The results of the testing proved the unit's suitability as a replacement for the existing system in its intended environment. The significance of this study is that a low cost replacement solution has been found for an industrial application by transferring modern technological knowledge to a small business. The company are now able to build on the design and take it into production, reducing servicing and production costs.

77 FR 61303 - Airworthiness Directives; Turbomeca S.A. Turboshaft Engines

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-09

...-mechanical metering unit (HMU). This proposed AD would require replacing the HMU at a reduced life. We are... pressure/low pressure (HP/LP) pump assembly within the hydro- mechanical metering unit (HMU), removed...-mechanical metering unit (HMU). We are issuing this AD to prevent an uncommanded in-flight shutdown of the...

KSC-08pd2071

NASA Image and Video Library

2008-07-18

CAPE CANAVERAL, Fla. – In the high bay of the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, the Orbital Replacement Unit Carrier for the Hubble Space Telescope is lifted from its transportation canister by workers from NASA's Goddard Space Flight Center. The Orbital Replacement Unit Carrier, or ORUC, is one of four carriers supporting hardware for space shuttle Atlantis' STS-125 mission to service the telescope. The Super Lightweight Interchangeable Carrier, or SLIC, and the Flight Support System, or FSS, at ground-level left, have also arrived at Kennedy. The Multi-Use Lightweight Equipment carrier will be delivered in late July. The carriers will be prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the Hubble servicing mission, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2072

NASA Image and Video Library

2008-07-18

CAPE CANAVERAL, Fla. – In the high bay of the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, the Orbital Replacement Unit Carrier for the Hubble Space Telescope is lowered onto a work platform by workers from NASA's Goddard Space Flight Center. The Orbital Replacement Unit Carrier, or ORUC, is one of four carriers supporting hardware for space shuttle Atlantis' STS-125 mission to service the telescope. The Super Lightweight Interchangeable Carrier, or SLIC, and the Flight Support System, or FSS, seen behind the ORUC, have also arrived at Kennedy. The Multi-Use Lightweight Equipment carrier will be delivered in late July. The carriers will be prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the Hubble servicing mission, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

Flow-Control Unit For Nitrogen And Hydrogen Gases

NASA Technical Reports Server (NTRS)

Chang, B. J.; Novak, D. W.

1990-01-01

Gas-flow-control unit installed and removed as one piece replaces system that included nine separately serviced components. Unit controls and monitors flows of nitrogen and hydrogen gases. Designed for connection via fluid-interface manifold plate, reducing number of mechanical fluid-interface connections from 18 to 1. Unit provides increasing reliability, safety, and ease of maintenance, and for reducing weight, volume, and power consumption.

Modernisation Issues of Diesel-Electric Shunting Locomotive Power Units

NASA Astrophysics Data System (ADS)

Hoimoja, Hardi; Jalakas, Tanel; Rosin, Argo; Rassylkin, Anton

2010-01-01

The research concentrates on the modernisation issues of inefficient diesel-electric shunting locomotives, produced in the former Soviet Union. The existing diesel-generator unit, serving as an onboard power plant can be replaced by hybridised units, with an energy storage unit acting as a peaking power source for dynamic modes. By integrating an energy storage unit into the power plant, the locomotive traction drive becomes hybridised, consuming less fuel during transients and idling.

78 FR 7770 - Boyce Hydro Power, LLC; Notice of Application Accepted for Filing, Soliciting Motions To...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-04

.... Description of Application: The licensee proposes to replace one of the project's three existing turbine/generator units with a new unit. The project's maximum hydraulic capacity would remain the same but the new...

Tungsten insulated susceptor cup for high temperature induction furnace eliminates contamination

NASA Technical Reports Server (NTRS)

Geringer, H. J.

1966-01-01

METILUR /Materials Experimental Tungsten Induction Laboratory Unit Replacement/ is an improved, unitized design of a susceptor cup and shielding that uses only one type of construction material /tungsten/ which eliminates contamination. Cycling runs can be accomplished with METILUR.

75 FR 13320 - Florida Power Corporation, et al., Crystal River Unit 3 Nuclear Generating Plant; Environmental...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-19

... replacement outage that is currently underway at CR-3. In addition to steam generators, other large components (e.g., moisture separators and large heat exchangers) are being replaced during this outage... on the Internet at the NRC Web site: http://www.nrc.gov/reading-rm/adams.html . Persons who do not...

A Three Degrees of Freedom Test-Bed for Nanosatellite and CubeSat Attitude Dynamics, Determination, and Control

DTIC Science & Technology

2009-12-01

Tactical Imaging Nano-sat Yielding Small-Cost Operations and Persistent Earth-coverage UFO UHF Follow On UHF Ultra-High Frequency USCG United...replaced by UHF Follow On ( UFO ) satellites in the 1990s. The UFO satellites are being updated and scheduled for replacement by the Mobile User

Mitochondrial Replacement Techniques: Divergence in Global Policy.

PubMed

Schandera, Johanna; Mackey, Tim K

2016-07-01

In 2015, the UK became the first country permitting the clinical application of mitochondrial replacement techniques (MRT). Here, we explore how MRT have led to diverging international policy. In response, we recommend focused regulatory efforts coupled with United Nations (UN) leadership to build international consensus on the future of MRT. Copyright © 2016 Elsevier Ltd. All rights reserved.

Evaluation of non-native Tsuga species as replacements for T. canadensis killed by hemlock woolly adelgid

Treesearch

Paul A. Weston; Richard W. Harper

2007-01-01

Several species of Tsuga from the western United States and Asia are under evaluation as potential replacements for T. canadensis being destroyed by hemlock woolly adelgid (Adelges tsugae Annand). Test plots were established in Katonah, NY in October, 2003, and trees were inoculated with adelgid egg masses in...

Enzyme replacement and substrate reduction therapy for Gaucher disease.

PubMed

Shemesh, Elad; Deroma, Laura; Bembi, Bruno; Deegan, Patrick; Hollak, Carla; Weinreb, Neal J; Cox, Timothy M

2015-03-27

Gaucher disease, a rare disorder, is caused by inherited deficiency of the enzyme glucocerebrosidase. It is unique among the ultra-orphan disorders in that four treatments are currently approved by various regulatory authorities for use in routine clinical practice. Hitherto, because of the relatively few people affected worldwide, many of whom started therapy during a prolonged period when there were essentially no alternatives to imiglucerase, these treatments have not been systematically evaluated in studies such as randomized controlled trials now considered necessary to generate the highest level of clinical evidence. To summarize all available randomized controlled study data on the efficacy and safety of enzyme replacement therapies and substrate reduction therapy for treating Gaucher disease. We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group's Inborn Errors of Metabolism Trials Register. Additional searches were conducted on ClinicalTrials.gov for any ongoing studies with potential interim results, and through PubMed. We also searched the reference lists of relevant articles and reviews.Date of last search: 07 August 2014. All randomized and quasi-randomized controlled studies (including open-label studies and cross-over studies) assessing enzyme replacement therapy or substrate reduction therapy, or both, in all types of Gaucher disease were included. Two authors independently assessed the risk of bias in the included studies, and extracted relevant data. Of the 488 studies retrieved by the electronic searches, eight met the inclusion criteria and were analysed (300 participants). Response parameters were restricted to haemoglobin concentration, platelet count, spleen and liver volume and serum biomarkers (chitotriosidase and CCL18). Only one publication reported a 'low risk of bias' score in all parameters assessed, and all studies included were randomized.Four studies reported the responses to enzyme replacement therapy of previously untreated individuals with type 1 Gaucher disease. Two studies investigated maintenance enzyme replacement therapy in people with stable type 1 Gaucher disease previously treated for at least two years. One study compared substrate reduction therapy, enzyme replacement therapy and a combination thereof as maintenance therapy in people with type 1 Gaucher disease previously treated with enzyme replacement therapy. One study examined substrate reduction therapy in people with chronic neuronopathic (type 3) Gaucher disease who continued to receive enzyme replacement therapy.Treatment-naïve participants had similar increases in haemoglobin when comparing those receiving imiglucerase or alglucerase at 60 units/kg, imiglucerase or velaglucerase alfa at 60 U/kg, taliglucerase alfa at 30 units/kg or 60 units/kg, and velaglucerase alfa at 45 units/g or 60 units/kg. For platelet count response in participants with intact spleens, a benefit for imiglucerase over velaglucerase alfa at 60 units/kg was observed, mean difference -79.87 (95% confidence interval -137.57 to -22.17). There were no other significant differences in platelet count response when comparing different doses of velaglucerase alfa and of taliglucerase alfa, and when comparing imiglucerase to alglucerase. Spleen and liver volume reductions were not significantly different in any enzyme replacement therapy product or dose comparison study. Although a dose effect on serum biomarkers was not seen after nine months, a significantly greater reduction with higher dose was reported after 12 months in the velaglucerase study, mean difference 16.70 (95% confidence intervaI 1.51 to 31.89). In the two enzyme replacement therapy maintenance studies comparing infusions every two weeks and every four weeks, there were no significant differences in haemoglobin concentration, platelet count, and spleen and liver volumes over a 6 to 12 month period when participants were treated with the same cumulative dose.A total of 25 serious adverse events were reported, nearly all deemed unrelated to treatment.There are, as yet, no randomized trials of substrate reduction therapy in treatment-naïve patients that can be evaluated. Miglustat monotherapy appeared as effective as continued enzyme replacement therapy for maintenance of hematological, organ and biomarker responses in people with type 1 Gaucher disease previously treated with imiglucerase for at least two years. In those with neuronopathic Gaucher disease, no significant improvements in haemoglobin concentration, platelet count or organ volumes occurred when enzyme replacement therapy was augmented with miglustat.One randomized controlled study assessing substrate reduction therapy was published immediately prior to producing the final version of this review, and this, along with a further ongoing study (expected to be published in the near future), will be assessed for eligibility in a future update of the review. The results reflect the limitations of analysing evidence restricted to prospective randomized controlled trials, especially when dealing with chronic rare diseases. This analysis suggests that, during the first year of treatment, different recombinant glucocerebrosidases are bio-similar and non-inferior in safety and efficacy for surrogate biological response parameters. Enzyme replacement therapy given at 30 to 45 units/kg body weight every two to four weeks was generally as effective as the 60 unit/kg dose for the assessed clinical outcomes. The analysis emphasise the need to determine whether it is realistic to carry out multi-decade prospective clinical trials for rare diseases such as type 1 Gaucher disease. With large treatment effects on the classical manifestations of the disorder, therapeutic investigations in Gaucher disease mandate innovative trial designs and methodology to secure decisive data concerning long-term efficacy and safety - with the realization that knowledge about disease-modifying actions that are sustained are of crucial importance to people with this chronic condition.

A Structured Professional Development Approach to Unit Study: The Experiences of 200 Teachers in a National Teacher Development Project.

ERIC Educational Resources Information Center

McColskey, Wendy; Parke, Helen; Furtak, Erin; Butler, Susan

This article addresses what was learned through the National Computational Science Leadership Program about involving teachers in planning high quality units of instruction around computational science investigations. Two cohorts of roughly 25 teacher teams nationwide were given opportunities to develop "replacement units." The goal was to support…

Hydrogen Fuel Cell on a Helicopter: A System Engineering Approach

NASA Astrophysics Data System (ADS)

Nesheiwat, Rod

Hydrogen fuel cells have been previously investigated as a viable replacement to traditional gas turbine auxiliary power unit onboard fixed wing commercial jets. However, so far no study has attempted to extend their applicability to rotary wing aircrafts. To aid in the advancement of such innovative technologies, a holistic technical approach is required to ensure risk reduction and cost effectiveness throughout the product lifecycle. This paper will evaluate the feasibility of replacing a gas turbine auxiliary power unit on a helicopter with a direct hydrogen, air breathing, proton exchange membrane fuel cell, all while emphasizing a system engineering approach that utilize a specialized set of tools and artifacts.

NASA Shuttle Logistics Depot (NSLD) - The application of ATE

NASA Technical Reports Server (NTRS)

Simpkins, Lorenz G.; Jenkins, Henry C.; Mauceri, A. Jack

1990-01-01

The concept of the NASA Shuttle Logistics Depot (NSLD) developed for the Space Shuttle Orbiter Program is described. The function of the NSLD at Cape Canaveral is to perform the acceptance and diagnostic testing of the Shuttle's space-rated line-replaceable units and shop-replaceable units (SRUs). The NSLD includes a comprehensive electronic automatic test station, program development stations, and assorted manufacturing support equipment (including thermal and vibration test equipment, special test equipment, and a card SRU test system). The depot activities also include the establishment of the functions for manufacturing of mechanical parts, soldering, welding, painting, clean room operation, procurement, and subcontract management.

ION SOURCE

DOEpatents

Brobeck, W.M.

1959-04-14

This patent deals with calutrons and more particularly to an arrangement therein whereby charged bottles in a calutron source unit may be replaced without admitting atmospheric air to the calutron vacuum chamber. As described, an ion unit is disposed within a vacuum tank and has a reservoir open toward a wall of the tank. A spike projects from thc source into the reservoir. When a charge bottle is placed in the reservoir, the spike breaks a frangible seal on the bottle. After the contents of the bottle are expended the bottle may be withdrawn and replaced with another charge bottle by a varuum lock arrangement in conjunction with an arm for manipulating the bottle.

Ion source

DOEpatents

Brobeck, W. M.

1959-04-14

This patent deals with calutrons and more particularly to an arrangement therein whereby charged bottles in a calutron source unit may be replaced without admitting atmospheric air to the calutron vacuum chamber. As described, an ion unit is disposed within a vacuum tank and has a reservoir open toward a wall of the tank. A spike projects from the source into the reservoir. When a charge bottle is placed in the reservoir, the spike breaks a frangible seal on the bottle. After the contents of the bottle are expended the bottle may be withdrawn and replaced with another charge bottle by a vacuum lock arrangement in conjunction with an arm for manipulating the bottle.

Has Embase replaced MEDLINE since coverage expansion?

PubMed

Lam, Michael Thomas; De Longhi, Christina; Turnbull, Joseph; Lam, Helen Rose; Besa, Reena

2018-04-01

The research tested the authors' hypothesis that more researchers from the academic medicine community in the United States and Canada with institutional access to Embase had started using Embase to replace MEDLINE since Embase was expanded in 2010 to cover all MEDLINE records. We contacted libraries of 140 and 17 medical schools in the United States and Canada, respectively, to confirm their subscriptions to Embase 5 years before and 5 years after 2010. We searched the names of institutions with confirmed Embase access in Ovid MEDLINE and Embase to retrieve works authored by affiliates of those institutions. We then examined 100 randomly selected records from each of the 5 years before and 5 years after the Embase coverage expansion in 2010. We hypothesized that studies that used Embase but not MEDLINE would increase due to the Embase coverage expansion. The number of studies that used Embase but not MEDLINE did not change between the pre-2010 and post-2010 periods. Our hypothesis was refuted. Studies that used Embase but not MEDLINE did not increase post-2010. Our results suggest the academic medicine community in the United States and Canada that had access did not use Embase to replace MEDLINE, despite the Embase coverage expansion.

Understanding Skill in EVA Mass Handling. Volume 1; Theoretical and Operational Foundations

NASA Technical Reports Server (NTRS)

Riccio, Gary; McDonald, Vernon; Peters, Brian; Layne, Charles; Bloomberg, Jacob

1997-01-01

This report describes the theoretical and operational foundations for our analysis of skill in extravehicular mass handling. A review of our research on postural control, human-environment interactions, and exploratory behavior in skill acquisition is used to motivate our analysis. This scientific material is presented within the context of operationally valid issues concerning extravehicular mass handling. We describe the development of meaningful empirical measures that are relevant to a special class of nested control systems: manual interactions between an individual and the substantial environment. These measures are incorporated into a unique empirical protocol implemented on NASA's principal mass handling simulator, the precision air-bearing floor, in order to evaluate skill in extravehicular mass handling. We discuss the components of such skill with reference to the relationship between postural configuration and controllability of an orbital replacement unit, the relationship between orbital replacement unit control and postural stability, the relationship between antecedent and consequent movements of an orbital replacement unit, and the relationship between antecedent and consequent postural movements. Finally, we describe our expectations regarding the operational relevance of the empirical results as it pertains to extravehicular activity tools, training, monitoring, and planning.

Should a coal-fired power plant be replaced or retrofitted?

PubMed

Patiño-Echeverri, Dalia; Morel, Benoit; Apt, Jay; Chen, Chao

2007-12-01

In a cap-and-trade system, a power plant operator can choose to operate while paying for the necessary emissions allowances, retrofit emissions controls to the plant, or replace the unit with a new plant. Allowance prices are uncertain, as are the timing and stringency of requirements for control of mercury and carbon emissions. We model the evolution of allowance prices for SO2, NOx, Hg, and CO2 using geometric Brownian motion with drift, volatility, and jumps, and use an options-based analysis to find the value of the alternatives. In the absence of a carbon price, only if the owners have a planning horizon longer than 30 years would they replace a conventional coal-fired plant with a high-performance unit such as a supercritical plant; otherwise, they would install SO2 and NOx, controls on the existing unit. An expectation that the CO2 price will reach $50/t in 2020 makes the installation of an IGCC with carbon capture and sequestration attractive today, even for planning horizons as short as 20 years. A carbon price below $40/t is unlikely to produce investments in carbon capture for electric power.

First non-OEM steam-generator replacement in US a success

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hendsbee, P.M.; Lees, M.D.; Smith, J.C.

1994-04-01

In selecting replacements for major powerplant components, a fresh approach can be advantageous--even when complex nuclear components are involved. This was the experience at Unit 2 of Millstone nuclear station, which features an 870-MW pressurized-water reactor (PWR) with two nuclear recirculating steam generators. The unit began operation in 1975. In the early 1980s, pitting problems surfaced in the steam generator tubing; by the mid eighties, tube corrosion had reached an unacceptable level. Virtually all of the 17,000 tubes in the two units were deteriorating, with 2500 plugged and 5000 sleeved. Several new problems also were identified, including secondary-side circumferential crackingmore » of the Alloy 600 tubing near the tubesheet face, and deterioration of the carbon steel egg-crate tube supports. Despite improvements to primary and secondary steam-generator water chemistry, including almost complete copper removal from the condensate and feedwater loops, Northeast Utilities (NU) was unable to completely control degradation of the tube bundles. The utility decided in 1987 that full replacement was the most viable alternative. NU made a bold move, selecting a supplier other than the original equipment manufacturer (OEM).« less

Recommendations for Enabling Manual Component Level Electronic Repair for Future Space Missions

NASA Technical Reports Server (NTRS)

Struk, Peter M.; Easton, John W.; Funk, Gregory P.; Latta, Gary S.; Ganster, Andrew W.; Estes, Brett E.

2011-01-01

Long duration missions to the Moon and Mars pose a number of challenges to mission designers, controllers, and the crews. Among these challenges are planning for corrective maintenance actions which often require a repair. Current repair strategies on the International Space Station (ISS) rely primarily on the use of Orbital Replacement Units (ORUs), where a faulty unit is replaced with a spare, and the faulty unit typically returns to Earth for analysis and possible repair. The strategy of replace to repair has posed challenges even for the ISS program. Repairing faulty hardware at lower levels such as the component level can help maintain system availability in situations where no spares exist and potentially reduce logistic resupply mass.This report provides recommendations to help enable manual replacement of electronics at the component-level for future manned space missions. The recommendations include hardware, tools, containment options, and crew training. The recommendations are based on the work of the Component Level Electronics Assembly Repair (CLEAR) task of the Exploration Technology Development Program from 2006 to 2009. The recommendations are derived based on the experience of two experiments conducted by the CLEAR team aboard the International Space Station as well as a group of experienced Miniature/Microminiature (2M) electronics repair technicians and instructors from the U.S. Navy 2M Project Office. The emphasis of the recommendations is the physical repair. Fault diagnostics and post-repair functional test are discussed in other CLEAR reports.

TOTAL KNEE REPLACEMENT IN PATIENTS WITH BELOW-KNEE AMPUTATION

PubMed Central

Karam, Matthew D; Willey, Michael; Shurr, Donald G

2010-01-01

Total knee replacement (TKR) is reserved for patients with severe and disabling arthritis that is non-responsive to conservative measures. Based on existing data, total knee replacement is a safe and cost-effective treatment for alleviating pain and improving physical function in patients who do not respond to conservative therapy. Despite the large variation in health status of patients and types of prosthesis implanted, total knee replacement has proven to be a relatively low risk and successful operation. Each year in the United States surgeons perform approximately 300,000 TKR.1 Likewise, lower extremity amputation is commonly performed in the United States with an annual incidence of 110,000 per year.2 Nearly 70% of all lower extremity amputations are performed as the result of chronic vascular disease, followed by trauma (22%), congenital etiology and tumor (4% each).3 Approximately 50% of all lower extremity amputations are performed secondary to complications from Diabetes Mellitus. Norvell et al. demonstrated that patients who have previously undergone transtibial amputation and ambulate with a prosthesis are more likely to develop degenerative joint disease in the con-tralateral extremity than the ipsilateral extremity.4 Further, radiographic changes consistent with osteoporosis have been demonstrated in up to 88% of limbs that have undergone transtibial amputation.8 To our knowledge, there have been only three reported cases of total knee replacement in patients with ipsilateral transtibial amputation.5,7 The purpose of the present study is to review the existing data on total knee replacement in patients who have undergone transtibial amputation. Further we present a patient with a transtibial amputation who underwent contralateral total knee replacement. PMID:21045987

40 CFR 270.4 - Effect of a permit.

Code of Federal Regulations, 2010 CFR

2010-07-01

... regarding leak detection systems for new and replacement surface impoundment, waste pile, and landfill units, and lateral expansions of surface impoundment, waste pile, and landfill units. The leak detection system requirements include double liners, CQA programs, monitoring, action leakage rates, and response...

KSC-2012-6381

NASA Image and Video Library

2012-12-04

CAPE CANAVERAL, Fla. -- Workers inside the Space Station Processing Facility at NASA's Kennedy Space Center in Florida position the orbital replacement unit for the space station's main bus switching unit as they prepare to pack the unit in a shipping container. The unit, which was processed at Kennedy, will be shipped to Japan at the beginning of the year for the HTV-4 launch, which is currently scheduled for 2013. Photo credit: NASA/Charisse Nahser

KSC-2012-6380

NASA Image and Video Library

2012-12-04

CAPE CANAVERAL, Fla. -- Workers inside the Space Station Processing Facility at NASA's Kennedy Space Center in Florida lift the orbital replacement unit for the space station's main bus switching unit as they prepare to pack the unit in a shipping container. The unit, which was processed at Kennedy, will be shipped to Japan at the beginning of the year for the HTV-4 launch, which is currently scheduled for 2013. Photo credit: NASA/Charisse Nahser

Steam generator feedwater nozzle transition piece replacement experience at Salem Unit 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Patten, D.B.; Perrin, J.S.; Roberts, A.T.

Cracking of steam generator feedwater piping adjacent to the feedwater nozzles has been a recurring problem since 1979 at Salem Unit 1 owned and operated by Public Service Electric and Gas Company. In addition to the cracking problem, erosion-corrosion at the leading edge of the feedwater nozzle thermal sleeve was also observed in 1992. To provide a long-term solution for the pipe cracking and thermal sleeve erosion-corrosion problems, a unique transition piece forging was specially designed, fabricated, and installed for each of the four steam generators during the 1995 outage. This paper discusses the design, fabrication, and installation of themore » transition piece forgings at Salem Unit 1, and the experiences gained from this project. It is believed that these experiences may help other utilities when planning similar replacements in the future.« less

Population Replacement and Immigrant Adaptation: New Issues Facing the West. Impact of Immigration in California, Policy Discussion Paper.

ERIC Educational Resources Information Center

Espenshade, Thomas J.

The low fertility of Western industrial nations is likely to become a permanent condition; in the absence of immigration, populations with below-replacement fertility will eventually decline in size. But at the same time fertility is declining, international migration to the West is accelerating. Legal immigration to the United States rose from…

Learner-Centered Instruction (LCI): Volume IV, The Simulated Maintenance Task Environment (SMTE): A Job Specific Simulator.

ERIC Educational Resources Information Center

Rifkin, Kenneth I.; And Others

The purpose of the simulated maintenance task environment is to provide a means for training and job performance testing of the flight line weapon control systems mechanic/technician for the F-111A aircraft. It provides practice in flight line equipment checkout, troubleshooting, and removal and replacement of line replaceable units in the…

Comparison of cropland and forest surface temperatures across the conterminous United States

EPA Science Inventory

Global climate models (GCM) investigating the effects of land cover on climate have found that replacing extra-tropical forest with cropland promotes cooling. We compared cropland and forest surface temperatures across the continental United States in 16 cells that were approxim...

Heterogeneity in preferences for woody biomass energy in the US Mountain West

Treesearch

Robert M. Campbell; Tyron J. Venn; Nathaniel M. Anderson

2018-01-01

The United States has passed legislation aimed at reducing greenhouse gas emissions (United States Congress, 2005; United States Congress, 2007; EPA, 2015). In order to achieve the goals set by these commitments, significant amounts of fossil fuel energy will need to be replaced with renewable energy. There are multiple renewable technologies from which to choose, and...

Greenhouse Gas Mitigation in Chinese Eco-Industrial Parks by Targeting Energy Infrastructure: A Vintage Stock Model.

PubMed

Guo, Yang; Tian, Jinping; Chertow, Marian; Chen, Lujun

2016-10-03

Mitigating greenhouse gas (GHG) emissions in China's industrial sector is crucial for addressing climate change. We developed a vintage stock model to quantify the GHG mitigation potential and cost effectiveness in Chinese eco-industrial parks by targeting energy infrastructure with five key measures. The model, integrating energy efficiency assessments, GHG emission accounting, cost-effectiveness analyses, and scenario analyses, was applied to 548 units of energy infrastructure in 106 parks. The results indicate that two measures (shifting coal-fired boilers to natural gas-fired boilers and replacing coal-fired units with natural gas combined cycle units) present a substantial potential to mitigate GHGs (42%-46%) compared with the baseline scenario. The other three measures (installation of municipal solid waste-to-energy units, replacement of small-capacity coal-fired units with large units, and implementation of turbine retrofitting) present potential mitigation values of 6.7%, 0.3%, and 2.1%, respectively. In most cases, substantial economic benefits also can be achieved by GHG emission mitigation. An uncertainty analysis showed that enhancing the annual working time or serviceable lifetime levels could strengthen the GHG mitigation potential at a lower cost for all of the measures.

Implementation and evaluation of an automated dispensing system.

PubMed

Schwarz, H O; Brodowy, B A

1995-04-15

An institution's experience in replacing a traditional unit dose cassette-exchange system with an automated dispensing system is described. A 24-hour unit dose cassette-exchange system was replaced with an automated dispensing system (Pyxis's Medstation Rx) on a 36-bed cardiovascular surgery unit and an 8-bed cardiovascular intensive care unit. Significantly fewer missing doses were reported after Medstation Rx was implemented. No conclusions could be made about the impact of the system on the reporting of medication errors. The time savings for pharmacy associated with the filling, checking, and delivery of new medication orders equated to about 0.5 full-time equivalent (FTE). Medstation Rx also saved substantial nursing time for acquisition of controlled substances and for controlled-substance inventory taking at shift changes. A financial analysis showed that Medstation Rx could save the institution about $1 million over five years if all personnel time savings could be translated into FTE reductions. The automated system was given high marks by the nurses in a survey; 80% wanted to keep the system on their unit. Pilot implementation of an automated dispensing system improved the efficiency of drug distribution over that of the traditional unit dose cassette-exchange system.

Overview of two story walkup flat type unit illustrating projecting ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Overview of two story walk-up flat type unit illustrating projecting balconies and concrete stairways. Original pipe railings replaced by square tube railing. Building 26, view facing east - Harbor Hills Housing Project, Two Story Walk-Up Type, 26607 Western Avenue, Lomita, Los Angeles County, CA

Parametric Mass Reliability Study

NASA Technical Reports Server (NTRS)

Holt, James P.

2014-01-01

The International Space Station (ISS) systems are designed based upon having redundant systems with replaceable orbital replacement units (ORUs). These ORUs are designed to be swapped out fairly quickly, but some are very large, and some are made up of many components. When an ORU fails, it is replaced on orbit with a spare; the failed unit is sometimes returned to Earth to be serviced and re-launched. Such a system is not feasible for a 500+ day long-duration mission beyond low Earth orbit. The components that make up these ORUs have mixed reliabilities. Components that make up the most mass-such as computer housings, pump casings, and the silicon board of PCBs-typically are the most reliable. Meanwhile components that tend to fail the earliest-such as seals or gaskets-typically have a small mass. To better understand the problem, my project is to create a parametric model that relates both the mass of ORUs to reliability, as well as the mass of ORU subcomponents to reliability.

Purification, crystallization, preliminary X-ray diffraction and molecular-replacement studies of great cormorant (Phalacrocorax carbo) haemoglobin

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jagadeesan, G.; Malathy, P.; Gunasekaran, K.

2014-10-25

The great cormorant hemoglobin has been isolated, purified and crystallized and the three dimensional structure is solved using molecular replacement technique. Haemoglobin is the iron-containing oxygen-transport metalloprotein that is present in the red blood cells of all vertebrates. In recent decades, there has been substantial interest in attempting to understand the structural basis and functional diversity of avian haemoglobins. Towards this end, purification, crystallization, preliminary X-ray diffraction and molecular-replacement studies have been carried out on cormorant (Phalacrocorax carbo) haemoglobin. Crystals were grown by the hanging-drop vapour-diffusion method using PEG 3350, NaCl and glycerol as precipitants. The crystals belonged to themore » trigonal system P3{sub 1}21, with unit-cell parameters a = b = 55.64, c = 153.38 Å, β = 120.00°; a complete data set was collected to a resolution of 3.5 Å. Matthews coefficient analysis indicated that the crystals contained a half-tetramer in the asymmetric unit.« less

Panoramic projection avionics displays

NASA Astrophysics Data System (ADS)

Kalmanash, Michael H.

2003-09-01

Avionics projection displays are entering production in advanced tactical aircraft. Early adopters of this technology in the avionics community used projection displays to replace or upgrade earlier units incorporating direct-view CRT or AMLCD devices. Typical motivation for these upgrades were the alleviation of performance, cost and display device availability concerns. In these systems, the upgraded (projection) displays were one-for-one form / fit replacements for the earlier units. As projection technology has matured, this situation has begun to evolve. The Lockheed-Martin F-35 is the first program in which the cockpit has been specifically designed to take advantage of one of the more unique capabilities of rear projection display technology, namely the ability to replace multiple small screens with a single large conformal viewing surface in the form of a panoramic display. Other programs are expected to follow, since the panoramic formats enable increased mission effectiveness, reduced cost and greater information transfer to the pilot. Some of the advantages and technical challenges associated with panoramic projection displays for avionics applications are described below.

Parallel Fin ORU Thermal Interface for space applications. [Orbital Replaceable Unit

NASA Technical Reports Server (NTRS)

Stobb, C. A.; Limardo, Jose G.

1992-01-01

The Parallel Fin Thermal Interface has been developed as an Orbital Replaceable Unit (ORU) interface. The interface transfers heat from an ORU baseplate to a Heat Acquisition Plate (HAP) through pairs of fins sandwiched between insert plates that press against the fins with uniform pressure. The insert plates are spread apart for ORU baseplate separation and replacement. Two prototype interfaces with different fin dimensions were built (Model 140 and 380). Interfacing surface samples were found to have roughnesses of 56 to 89 nm. Conductance values of 267 to 420 W/sq m C were obtained for the 140 model in vacuum with interface pressures of 131 to 262 kPa (19 to 38 psi). Vacuum conductances ranging from 176 to 267 W/sq m F were obtained for the 380 model at interface pressures of 97 to 152 kPa (14 and 22 psi). Correlations from several sources were found to agree with test data within 20 percent using thermal math models of the interfaces.

Expedition 28 Crew Members during IFM

NASA Image and Video Library

2011-06-30

ISS028-E-010781 (30 June 2011) --- NASA astronauts Mike Fossum (left) and Ron Garan, both Expedition 28 flight engineers, perform in-flight maintenance in the Harmony node of the International Space Station. The maintenance involved removing and replacing the failed Common Cabin Air Assembly (CCAA) heat exchanger in the P3 Midbay with a new spare Heat Exchanger Orbit Replaceable Unit (HX ORU) and lines.

Projecting the need for hip replacement over the next three decades: influence of changing demography and threshold for surgery

PubMed Central

Birrell, F.; Johnell, O.; Silman, A.

1999-01-01

OBJECTIVES—To estimate the requirement for total hip replacement in the United Kingdom over the next three decades
METHODS—Projection of age and sex specific hip replacements in the UK over 10 year intervals taking account of demographic change and the extrapolation of arthroplasty rates from Sweden; a country with recently introduced guidelines.
RESULTS—Assuming no change in the age and sex specific arthroplasty rates, the estimated number of hip replacements will increase by 40% over the next 30 year period because of demographic change alone. The proportionate change will be substantially higher in men (51%) than women (33%), with a doubling of the number of male hip replacements in those aged over 85. Changes in the threshold for surgery may increase this further—up to double the current number.
CONCLUSION—A sharp rise in hip replacements will be needed to satisfy needs in the UK population over the next 30 years.

 PMID:10460191

Metro U.S.A. Data Sheet: Population Estimates and Selected Demographic Indicators for the Metropolitan Areas of the United States. Special edition of the United States Population Data Sheet.

ERIC Educational Resources Information Center

Population Reference Bureau, Inc., Washington, DC.

This poster-size data sheet presents population estimates and selected demographic indicators for the nation's 281 metropolitan areas. These areas are divided into 261 Metropolitan Statistical Areas (MSAs) and 20 Consolidated Metropolitan Statistical Areas (CMSAs), reporting units which replace the Standard Metropolitan Statistical Areas (SMSAs)…

KSC-2012-6382

NASA Image and Video Library

2012-12-04

CAPE CANAVERAL, Fla. -- Inside the Space Station Processing Facility at NASA's Kennedy Space Center in Florida, workers have prepared the orbital replacement unit for the space station's main bus switching unit to be placed in a shipping container. The unit, which was processed at Kennedy, will be shipped to Japan at the beginning of the year for the HTV-4 launch, which is currently scheduled for 2013. Photo credit: NASA/Charisse Nahser

KSC-2012-6378

NASA Image and Video Library

2012-12-04

CAPE CANAVERAL, Fla. -- Workers inside the Space Station Processing Facility at NASA's Kennedy Space Center in Florida prepare to pack the orbital replacement unit for the space station's main bus switching unit in a shipping container. The unit, which was processed at Kennedy, will be shipped to Japan at the beginning of the year for the HTV-4 launch, which is currently scheduled for 2013. Photo credit: NASA/Charisse Nahser

KSC-2012-6379

NASA Image and Video Library

2012-12-04

CAPE CANAVERAL, Fla. -- Workers inside the Space Station Processing Facility at NASA's Kennedy Space Center in Florida prepare to pack the orbital replacement unit for the space station's main bus switching unit in a shipping container. The unit, which was processed at Kennedy, will be shipped to Japan at the beginning of the year for the HTV-4 launch, which is currently scheduled for 2013. Photo credit: NASA/Charisse Nahser

The United States Army’s Full-Spectrum Training Strategy Challenge

DTIC Science & Technology

2012-05-17

the high operational tempo for deployed and deploying units. Soldiers and units conducted repeat deployments to both Iraq and Afghanistan with little...prevalent in Strategic Operational Design and associated variations of design. Further complicating Israeli ideas of warfare was the notion that...Army to develop an overarching operational framework that finally replaces Airland Battle, like EBO or some variation of operational design. But one

SI units and the clinical practice of infectious diseases: application to the usage of antimicrobial agents.

PubMed

Quentzel, H L; Nadelman, R B; Ng, J; Wormser, G P

1989-01-01

Over the next few years, le Système international d'Unités or SI units may replace the presently used metric system in reporting laboratory data. The change to SI units will likely result in some confusion among clinicians who are not well versed in the new system. Application of SI units to the clinical practice of infectious diseases is discussed, including changes in drug dosages, serum drug levels, and minimum inhibitory concentrations. A table is presented to facilitate conversion of metric units to SI units and vice versa.

75 FR 27385 - Petition for Waiver of Compliance

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-14

... identifying mark, type of car, year built, number of windows and the estimated replacement glazing cost for...'s arguments in favor of relief. United Railroad Historical Society of New Jersey [Docket Number FRA-2010-0079] The United Railroad Historical Society of New Jersey (URHS) of Jackson, New Jersey, has...

Clinical and Radiographic Assessment of Reasons for Replacement of Metal- Ceramic Fixed Dental Prostheses in Patients Referring to Dental School.

PubMed

Al Refai, Roa'a; Saker, Samah

2018-01-01

The expected length of service and reasons for fixed dental prostheses (FDPs) replacement are a frequent inquiry by patients while the answers were mainly based on studies reports that was conducted outside the middle east region. This clinical and radiographic survey was constructed to assess and survey clinically and radiographically the reasons of replacement of metal-ceramic fixed dental prostheses, amongst patients reporting at dental school in Taibah University. Between January and May 2016, 151 patients were recruited for this study. Interview (include questions pertained to the length of service of the prosthesis, the nature of complaint as told by patient in her own words), clinical examination, intra-oral photographs, and periapical radiographs, were done by the researchers. The parameters assessed were secondary caries, open margins, loss of retention, failure of endodontic treatment of the abutment and periodontal diseases. A total number of 249 failed fixed dental prostheses were evaluated. Of which 180 (39.7%) were single crowns, 159 (35.0%) were retainers and 117 (25.8%) were pontics in 69 fixed partial denture. The most common reason for replacement of fixed restorations was periodontal diseases affecting 92.8% of all types' restorations, followed by defective margin in 90.4% of examined restoration, poor aesthetic in 88% of restorations, while periapical involvement was found in 85.5% of fixed dental prosthesis. The survival rates of fixed prostheses were not predictable, and no association was found between number of years in service and the number of restorations. The most common reasons for replacing single unit fixed dental prostheses are periodontal diseases and periapical involvement, while defective margins and poor aesthetic mainly associated with multi-unit fixed dental prostheses. Key words: Failure, Fixed dental prosthesis, Survival, Replacement.

OGS Hydrogen Sensor ORU R&R

NASA Image and Video Library

2012-04-18

ISS030-E-236919 (18 April 2012) --- NASA astronaut Dan Burbank, Expedition 30 commander, works with the Oxygen Generator System (OGS) rack in the Tranquility node of the International Space Station. Burbank unpowered the OGS, purged the hydrogen sensor Orbital Replacement Unit (ORU) with the Hydrogen Sensor ORU Purge Adapter (HOPA) for return to Earth, and replaced the hydrogen sensor with a new spare, then cleaned the rack Avionics Air Assembly (AAA).

VHSIC Electronics and the Cost of Air Force Avionics in the 1990s

DTIC Science & Technology

1990-11-01

circuit. LRM Line replaceable module. LRU Line replaceable unit. LSI Large-scale integration. LSTTL Tow-power Schottky Transitor -to-Transistor Logic...displays, communications/navigation/identification, electronic combat equipment, dispensers, and computers. These CERs, which statistically relate the...some of the reliability numbers, and adding the F-15 and F-16 to obtain the data sample shown in Table 6. Both suite costs and reliability statistics

A Procedure for Determining the Resource Utilization Potential of Coal Ash.

DTIC Science & Technology

1981-09-01

48 V Chapter Page Lime Replacement for Flue - Gas Desulfurization Ujnits . .. .. .. .. .. .. .. .. .. .. . .48 Refuse Pile Fire Abatemnent...exceeds the capability of a vacuum system to attain a satisfactory conveying rate. If thenfy ash is removed from the flue gas stream by a wet collector...the mixture some fertilizer value (21:44-45). Lime Replacement for Flue - Gas Desulfurization Units For conventional SO, lime-based removal systems

26. Generator Voltage Regulator Cabinet Exterior for Unit 1, view ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

26. Generator Voltage Regulator Cabinet Exterior for Unit 1, view to the northwest. The exciter supplies the DC current to the generator rotor to create electricity. Each of the four original units has an exciter identical to this one, and all are scheduled for replacement. - Washington Water Power Clark Fork River Noxon Rapids Hydroelectric Development, Powerhouse, South bank of Clark Fork River at Noxon Rapids, Noxon, Sanders County, MT

Assessment of the Capability of the NGDS Prototype to Replace the JBAIDS for Environmental Sample Analysis

DTIC Science & Technology

2016-11-01

FilmArray system. 15. SUBJECT TERMS BioFire FilmArray system Dry Filter Unit (DFU) Joint Biological...collectors, such as the Dry Filter Unit (DFU). The FilmArray system showed enormous potential to rapidly screen samples for a wide range of biological...specific focus on the efficient implementation of environmental detectors and collectors, such as Dry Filter Units (DFUs). The JUPITR ATD members

Management of the patient with a total joint replacement: the primary care practitioner's role.

PubMed

Palmer, L M

1999-01-01

The primary care practitioner assumes chief responsibility for patients with arthritis. More than 40 million Americans experience some form of arthritis. Management of the patient with arthritis may include a referral to an orthopedic surgeon for surgical intervention. As estimated, up to 500,000 total joint replacement procedures are performed by orthopedic surgeons each year in the United States. Presurgical evaluation for a total joint replacement is imperative to ensure that the patient can safely undergo this surgical procedure. Postsurgical care of a patient with total joint replacement involves coordinating care with the physical therapist and orthopedic surgeon to ensure adequate follow-through with the recommended rehabilitation program, prophylactic antibiotic coverage, and observation for any complications including infection, deep-vein thrombosis, or loosening of the total-joint prosthesis.

Contemporary Fertility Patterns and First-Birth Timing among Mexican-Origin Women

ERIC Educational Resources Information Center

Batson, Christie D.

2013-01-01

This article examines first-birth timing among Mexican women in the United States over two birth cohorts. Currently, Mexican women are one of a small group that maintains above-replacement fertility in the United States, contributing to both Mexican population growth and overall national population growth. Yet, the fertility timing of Mexican…

The 1956 Suez Crisis and the United Nations

DTIC Science & Technology

2004-06-17

formally given them the “ scarlet letter.” He then proceeds to describe the crisis as “the first time that permanent members of the Security Council had...less fanfare. Jubilant crowds of Egyptians replaced them. By midday on 23 December, the merriment reached a fevered pitch when units of the “defeated

77 FR 42653 - United States Navy Restricted Area, SUPSHIP Gulf Coast Detachment Mobile at AUSTAL, USA, Mobile...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-20

... restricted area established around the AUSTAL, USA shipbuilding facility located in Mobile, Alabama. The Supervisor of Shipbuilding, Conversion and Repair, United States Navy (USN), Gulf Coast (SUPSHIP Gulf Coast..., 2011, replacing the Supervisor of Shipbuilding, Conversion, and Repair, USN, Bath (SUPSHIP Bath). The...

76 FR 17362 - Airworthiness Directives; Bombardier, Inc. Model DHC-8-400 Series Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-29

... elevator power control units (PCUs) where the shaft (tailstock) swaged bearing liners had shown a higher... on the elevator power control units (PCUs) where the shaft (tailstock) swaged bearing liners had...-play check of the shaft swaged bearing installed in the elevator PCU tailstock end and replacement of...

42 CFR 409.87 - Blood deductible.

Code of Federal Regulations, 2012 CFR

2012-10-01

... after plasma is separated from whole blood. (2) A unit of packed red cells is treated as the equivalent...) Exception. The beneficiary is not responsible for the first 3 units of whole blood or packed red cells if.... In that case, the blood or red cells is deemed to have been replaced. (c) Provider's right to charge...

42 CFR 409.87 - Blood deductible.

Code of Federal Regulations, 2011 CFR

2011-10-01

... after plasma is separated from whole blood. (2) A unit of packed red cells is treated as the equivalent...) Exception. The beneficiary is not responsible for the first 3 units of whole blood or packed red cells if.... In that case, the blood or red cells is deemed to have been replaced. (c) Provider's right to charge...

42 CFR 409.87 - Blood deductible.

Code of Federal Regulations, 2014 CFR

2014-10-01

... after plasma is separated from whole blood. (2) A unit of packed red cells is treated as the equivalent...) Exception. The beneficiary is not responsible for the first 3 units of whole blood or packed red cells if.... In that case, the blood or red cells is deemed to have been replaced. (c) Provider's right to charge...

42 CFR 409.87 - Blood deductible.

Code of Federal Regulations, 2013 CFR

2013-10-01

... after plasma is separated from whole blood. (2) A unit of packed red cells is treated as the equivalent...) Exception. The beneficiary is not responsible for the first 3 units of whole blood or packed red cells if.... In that case, the blood or red cells is deemed to have been replaced. (c) Provider's right to charge...

STS-82 Discovery payloads being integrated in VPF

NASA Image and Video Library

1997-01-30

KENNEDY SPACE CENTER, FLORIDA STS-82 PREPARATIONS VIEW --- Payload processing workers in the Kennedy Space Center (KSC) Vertical Processing Facility (VPF) prepare to integrate the Space Telescope Imaging Spectrograph (STIS), suspended at center, into the Orbiter Replacement Unit (ORU) Carrier and Scientific Instrument Protective Enclosure (SIPE). STIS will replace the Goddard High Resolution Spectrograph (GHRS) on the Hubble Space Telescope (HST). Four of the seven STS-82 crew members will perform a series of spacewalks to replace two scientific instruments with two new instruments, including STIS, and perform other tasks during the second HST servicing mission. HST was deployed nearly seven years ago and was initially serviced in 1993.

Implementation of a timed, electronic, assessment-driven potassium-replacement protocol.

PubMed

Zielenski, Christopher; Crabtree, Adam; Le, Tien; Marlatt, Alyse; Ng, Dana; Tran, Alan

2017-06-15

The adherence to and effectiveness and safety of a timed, electronic, assessment-driven potassium-replacement protocol (TARP) were compared with an electronic nurse-driven replacement protocol (NRP) are reported. A retrospective observational study was conducted in a community hospital evaluating protocol adherence, effectiveness, and safety for 2 potassium-replacement protocols. All adults on medical units with an order for potassium replacement per protocol during the 3-month trial periods were reviewed. All patients requiring potassium replacement per protocol were included in the analysis. Adherence to the protocol was assessed by evaluating the dose of potassium administered and performance of reassessments. Effectiveness of the protocol was assessed by evaluating the time to achieve target potassium levels. Safety was assessed by evaluating the route of administration and occurrence of hyperkalemia. A total of 300 patients treated using potassium-replacement protocols required potassium replacement during the study period, with 148 patients in the NRP group requiring 491 instances of potassium replacement. In the TARP group a total of 564 instances requiring potassium replacement corresponded to 152 patients. Of the 491 instances requiring replacement in the NRP group, the correct dose was administered and reassessment performed 117 times (23.8%). Overall adherence ( p < 0.05), correct dose given ( p < 0.05), average time from blood draw to potassium replacement ( p < 0.0001), use of oral replacement ( p < 0.05), and time to achieve target potassium level within 12 hours ( p < 0.05) were significantly improved in the TARP group. The TARP improved the effectiveness and safety of potassium-replacement therapy over the traditional NRP without negatively affecting timeliness of care. Copyright © 2017 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

Expression, purification, crystallization and preliminary crystallographic study of isolated modules of the mouse coactivator-associated arginine methyltransferase 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Troffer-Charlier, Nathalie; Cura, Vincent; Hassenboehler, Pierre

2007-04-01

Isolated modules of mouse coactivator-associated arginine methyltransferase 1 encompassing the protein arginine N-methyltransferase catalytic domain have been overexpressed, purified and crystallized. X-ray diffraction data have been collected and have enabled determination of the structures by multiple isomorphous replacement using anomalous scattering. Coactivator-associated arginine methyltransferase 1 (CARM1) plays a crucial role in gene expression as a coactivator of several nuclear hormone receptors and also of non-nuclear receptor systems. Its recruitment by the transcriptional machinery induces protein methylation, leading to chromatin remodelling and gene activation. CARM1{sub 28–507} and two structural states of CARM1{sub 140–480} were expressed, purified and crystallized. Crystals of CARM1{submore » 28–507} belong to space group P6{sub 2}22, with unit-cell parameters a = b = 136.0, c = 125.3 Å; they diffract to beyond 2.5 Å resolution using synchrotron radiation and contain one monomer in the asymmetric unit. The structure of CARM1{sub 28–507} was solved by multiple isomorphous replacement and anomalous scattering methods. Crystals of apo CARM1{sub 140–480} belong to space group I222, with unit-cell parameters a = 74.6, b = 99.0, c = 207.4 Å; they diffract to beyond 2.7 Å resolution and contain two monomers in the asymmetric unit. Crystals of CARM1{sub 140–480} in complex with S-adenosyl-l-homocysteine belong to space P2{sub 1}2{sub 1}2, with unit-cell parameters a = 74.6, b = 98.65, c = 206.08 Å; they diffract to beyond 2.6 Å resolution and contain four monomers in the asymmetric unit. The structures of apo and holo CARM1{sub 140–480} were solved by molecular-replacement techniques from the structure of CARM1{sub 28–507}.« less

Use of mock-up training to reduce personnel exposure at the North Anna Unit 1 Steam Generator Replacement Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Henry, H.G.; Reilly, B.P.

1995-03-01

The North Anna Power Station is located on the southern shore of Lake Anna in Louisa County, approximately forty miles northwest of Richmond, Virginia. The two 910 Mw nuclear units located on this site are owned by Virginia Electric and Power Company (Virginia Power) and Old Dominion Electric Cooperative and operated by Virginia Power. Fuel was loaded into Unit 1 in December 1977, and it began commercial operation in June 1978. Fuel was loaded into Unit 2 in April 1980 and began commercial operation in December 1980. Each nuclear unit includes a three-coolant-loop pressurized light water reactor nuclear steam supplymore » system that was furnished by Westinghouse Electric Corporation. Included within each system were three Westinghouse Model 51 steam generators with alloy 600, mill-annealed tubing material. Over the years of operation of Unit 1, various corrosion-related phenomena had occurred that affected the steam generators tubing and degraded their ability to fulfill their heat transfer function. Advanced inspection and repair techniques helped extend the useful life of the steam generators, but projections based on the results of the inspections indicated that the existing steam generators tubing and degraded their ability to fullfill their heat transfer function. Advanced inspection and repair techniques helped extend the useful life of the steam generators, but projections based on the results of the inspections indicated that the existing steam generators would not last their design life and must be repaired. To this end Virginia Power determined that a steam generator replacement (SGR) program was necessary to remove the old steam generator tube bundles and lower shell sections, including the channel heads (collectively called the lower assemblies), and replace them with new lower assemblies incorporating design features that will prevent the degradation problems that the old steam generators had experienced.« less

Bleacher Comforts.

ERIC Educational Resources Information Center

Scandrett, Donald G.

1998-01-01

Examines the planning issues when replacing telescoping bleacher units and for analyzing seating options. Adresses the importance of complying with local building codes and the considerations on maintenance following installation. (GR)

Increased calcium supplementation is associated with morbidity and mortality in the infant postoperative cardiac patient.

PubMed

Dyke, Peter C; Yates, Andrew R; Cua, Clifford L; Hoffman, Timothy M; Hayes, John; Feltes, Timothy F; Springer, Michelle A; Taeed, Roozbeh

2007-05-01

The purpose of this study was to assess the association of calcium replacement therapy with morbidity and mortality in infants after cardiac surgery involving cardiopulmonary bypass. Retrospective chart review. The cardiac intensive care unit at a tertiary care children's hospital. Infants undergoing cardiac surgery involving cardiopulmonary bypass between October 2002 and August 2004. None. Total calcium replacement (mg/kg calcium chloride given) for the first 72 postoperative hours was measured. Morbidity and mortality data were collected. The total volume of blood products given during the first 72 hrs was recorded. Infants with confirmed chromosomal deletions at the 22q11 locus were noted. Correlation and logistic regression analyses were used to generate odds ratios and 95% confidence intervals, with p < .05 being significant. One hundred seventy-one infants met inclusion criteria. Age was 4 +/- 3 months and weight was 4.9 +/- 1.7 kg at surgery. Six infants had deletions of chromosome 22q11. Infants who weighed less required more calcium replacement (r = -.28, p < .001). Greater calcium replacement correlated with a longer intensive care unit length of stay (r = .27, p < .001) and a longer total hospital length of stay (r = .23, p = .002). Greater calcium replacement was significantly associated with morbidity (liver dysfunction [odds ratio, 3.9; confidence interval, 2.1-7.3; p < .001], central nervous system complication [odds ratio, 1.8; confidence interval, 1.1-3.0; p = .02], infection [odds ratio, 1.5; confidence interval, 1.0-2.2; p < .04], extracorporeal membrane oxygenation [odds ratio, 5.0; confidence interval, 2.3-10.6; p < .001]) and mortality (odds ratio, 5.8; confidence interval, 5.8-5.9; p < .001). Greater calcium replacement was not associated with renal insufficiency (odds ratio, 1.5; confidence interval, 0.9-2.3; p = .07). Infants with >1 sd above the mean of total calcium replacement received on average fewer blood products than the total study population. Greater calcium replacement is associated with increasing morbidity and mortality. Further investigation of the etiology and therapy of hypocalcemia in this population is warranted.

Portable Hydraulic Powerpack

NASA Technical Reports Server (NTRS)

Anderson, L. A.; Henry, R. L.; Fedor, O. H.; Owens, L. J.

1986-01-01

Rechargeable hydraulic powerpack functions as lightweight, compact source of mechanical energy. Self-contained hydraulic powerpack derives energy from solid chemical charge. Combustion of charge initiated by small hammer, and revolving feeder replaces charges expended. Combustion gases cool during expansion in turbine and not too hot for release to atmosphere. Unit has applications driving wheelchairs and operating drills, winches, and other equipment in remote areas. Also replaces electric motors and internal-combustion engines as source of power in explosive atmospheres.

A Case Study of Internet Protocol Telephony (IPT) Implementation at United States Coast Guard Headquarters

DTIC Science & Technology

2005-03-01

conversations over data networks . Many organizations are replacing portions of their traditional phone systems to gain the benefits of cost savings and...relevant to the Coast Guard. It includes the discussion of the public switched telephone network , an overview of IPT, IPT security issues, the...transmitting voice conversations over data networks . Many organizations are replacing portions of their traditional phone systems to gain the benefits of

Burbank performs Part 1 of the WRS-1 Repair

NASA Image and Video Library

2012-03-08

ISS030-E-128752 (8 March 2012) --- NASA astronaut Dan Burbank, Expedition 30 commander, performs part one of the Water Recovery System-1 (WRS-1) repair in the Tranquility node of the International Space Station. Burbank removed and replaced the failed Catalytic Reactor (CR), and installed a temporary filter kit between the new CR and the Microbial Check Valve (MCV) to support a system flush of the new Orbital Replacement Unit (ORU).

The optimal hormonal replacement modality selection for multiple organ procurement from brain-dead organ donors

PubMed Central

Mi, Zhibao; Novitzky, Dimitri; Collins, Joseph F; Cooper, David KC

2015-01-01

The management of brain-dead organ donors is complex. The use of inotropic agents and replacement of depleted hormones (hormonal replacement therapy) is crucial for successful multiple organ procurement, yet the optimal hormonal replacement has not been identified, and the statistical adjustment to determine the best selection is not trivial. Traditional pair-wise comparisons between every pair of treatments, and multiple comparisons to all (MCA), are statistically conservative. Hsu’s multiple comparisons with the best (MCB) – adapted from the Dunnett’s multiple comparisons with control (MCC) – has been used for selecting the best treatment based on continuous variables. We selected the best hormonal replacement modality for successful multiple organ procurement using a two-step approach. First, we estimated the predicted margins by constructing generalized linear models (GLM) or generalized linear mixed models (GLMM), and then we applied the multiple comparison methods to identify the best hormonal replacement modality given that the testing of hormonal replacement modalities is independent. Based on 10-year data from the United Network for Organ Sharing (UNOS), among 16 hormonal replacement modalities, and using the 95% simultaneous confidence intervals, we found that the combination of thyroid hormone, a corticosteroid, antidiuretic hormone, and insulin was the best modality for multiple organ procurement for transplantation. PMID:25565890

A stand-replacing fire history in upper montane forests of the southern Rocky Mountains

USGS Publications Warehouse

Margolis, E.Q.; Swetnam, T.W.; Allen, Craig D.

2007-01-01

Dendroecological techniques were applied to reconstruct stand-replacing fire history in upper montane forests in northern New Mexico and southern Colorado. Fourteen stand-replacing fires were dated to 8 unique fire years (1842–1901) using four lines of evidence at each of 12 sites within the upper Rio Grande Basin. The four lines of evidence were (i) quaking aspen (Populus tremuloides Michx.) inner-ring dates, (ii) fire-killed conifer bark-ring dates, (iii) tree-ring width changes or other morphological indicators of injury, and (iv) fire scars. The annual precision of dating allowed the identification of synchronous stand-replacing fire years among the sites, and co-occurrence with regional surface fire events previously reconstructed from a network of fire scar collections in lower elevation pine forests across the southwestern United States. Nearly all of the synchronous stand-replacing and surface fire years coincided with severe droughts, because climate variability created regional conditions where stand-replacing fires and surface fires burned across ecosystems. Reconstructed stand-replacing fires that predate substantial Anglo-American settlement in this region provide direct evidence that stand-replacing fires were a feature of high-elevation forests before extensive and intensive land-use practices (e.g., logging, railroad, and mining) began in the late 19th century.

Shopping around for hospital services: a comparison of the United States and Canada.

PubMed

Bell, C M; Crystal, M; Detsky, A S; Redelmeier, D A

1998-04-01

Historical comparisons indicate that US hospitals are more expensive than Canadian hospitals, but health care system reform might have changed the relative costs and timeliness of health care in the 2 countries. To estimate the price and convenience of selected hospital services in the United States and Canada for patients in 1997 had they paid out-of-pocket. Cross-sectional telephone survey conducted May 1996 to April 1997. The 2 largest acute care general hospitals from every city in the United States and Canada with a population greater than 500000. Each hospital was telephoned and asked their price and waiting time for 7 services: magnetic resonance imaging of the head without gadolinium; a screening mammogram; a 12-lead electrocardiogram; a prothrombin time measurement; a session of hemodialysis; a screening colonoscopy; and a total knee replacement. Waiting times were measured in days until earliest appointment and charges were converted to American currency. Overall, 48 US and 18 Canadian hospitals were surveyed. Median waiting times were significantly shorter in American hospitals for 4 services, particularly a magnetic resonance imaging of the head (3 days vs 150 days; P<.001). Median charges were significantly higher in American hospitals for 6 services, particularly for a total knee replacement ($26805 vs $10651; P<.001). Individual services showed no association between shorter waiting times and higher prices within each country, with the exception of a total knee replacement in the United States. US hospitals still provide higher prices and faster care than Canadian hospitals for patients who pay out-of-pocket.

Delay in onset of metabolic alkalosis during regional citrate anti-coagulation in continuous renal replacement therapy with calcium-free replacement solution.

PubMed

See, Kay Choong; Lee, Margaret; Mukhopadhyay, Amartya

2009-01-01

Regional citrate anti-coagulation for continuous renal replacement therapy chelates calcium to produce the anti- coagulation effect. We hypothesise that a calcium-free replacement solution will require less citrate and produce fewer metabolic side effects. Fifty patients, in a Medical Intensive Care Unit of a tertiary teaching hospital (25 in each group), received continuous venovenous hemofiltration using either calcium-containing or calcium-free replacement solutions. Both groups had no significant differences in filter life, metabolic alkalosis, hypernatremia, hypocalcemia, and hypercalcemia. However, patients using calcium-containing solution developed metabolic alkalosis earlier, compared to patients using calcium-free solution (mean 24.6 hours,CI 0.8-48.4 vs. 37.2 hours, CI 9.4-65, P = 0.020). When calcium-containing replacement solution was used, more citrate was required (mean 280 ml/h, CI 227.2-332.8 vs. 265 ml/h, CI 203.4-326.6, P = 0.069), but less calcium was infused (mean 21.2 ml/h, CI 1.2-21.2 vs 51.6 ml/h, CI 26.8-76.4, P < or = 0.0001).

Dipolar-dephasing 13C NMR studies of decomposed wood and coalified xylem tissue: Evidence for chemical structural changes associated with defunctionalization of lignin structural units during coalification

USGS Publications Warehouse

Hatcher, P.G.

1988-01-01

A series of decomposed and coalified gymnosperm woods was examined by conventional solid-state 13C nuclear magnetic resonance (NMR) and by dipolar-dephasing NMR techniques. The results of these NMR studies for a histologically related series of samples provide clues as to the nature of codification reactions that lead to the defunctionalization of lignin-derived aromatic structures. These reactions sequentially involve the following: (1) loss of methoxyl carbons from guaiacyl structural units with replacement by hydroxyls and increased condensation; (2) loss of hydroxyls or aryl ethers with replacement by hydrogen as rank increases from lignin to high-volatile bituminous coal; (3) loss of alkyl groups with continued replacement by hydrogen. The dipolar-dephasing data show that the early stages of coalification in samples examined (lignin to lignite) involve a decreasing degree of protonation on aromatic rings and suggest that condensation is significant during coalification at this early stage. An increasing degree of protonation on aromatic rings is observed as the rank of the sample increases from lignite to anthracite.

Soldering in a Reduced Gravity Environment (SoRGE)

NASA Technical Reports Server (NTRS)

Easton, John W.; Struk, Peter M.

2012-01-01

Future long-duration human exploration missions will be challenged by constraints on mass and volume allocations available for spare parts. Addressing this challenge will be critical to the success of these missions. As a result, it is necessary to consider new approaches to spacecraft maintenance and repair that reduce the need for large replacement components. Currently, crew members on the International Space Station (ISS) recover from faults by removing and replacing, using backup systems, or living without the function of Orbital Replacement Units (ORUs). These ORUs are returned to a depot where the root cause of the failure is determined and the ORU is repaired. The crew has some limited repair capability with the Modulation/DeModulation (MDM) ORU, where circuit cards are removed and replace in faulty units. The next step to reducing the size of the items being replaced would be to implement component-level repair. This mode of repair has been implemented by the U.S. Navy in an operational environment and is now part of their standard approach for maintenance. It is appropriate to consider whether this approach can be adapted for future spaceflight operations. To this end, the Soldering in a Reduced Gravity Environment (SoRGE) experiment studied the effect of gravity on the formation of solder joints on electronic circuit boards. This document describes the SoRGE experiment, the analysis methods, and results to date. This document will also contain comments from the crew regarding their experience conducting the SoRGE experiment as well as recommendations for future improvements. Finally, this document will discuss the plans for the SoRGE samples which remain on ISS.

Maternal cfDNA screening for Down syndrome--a cost sensitivity analysis.

PubMed

Cuckle, Howard; Benn, Peter; Pergament, Eugene

2013-07-01

This study aimed to determine the principal factors contributing to the cost of avoiding a birth with Down syndrome by using cell-free DNA (cfDNA) to replace conventional screening. A range of unit costs were assigned to each item in the screening process. Detection rates were estimated by meta-analysis and modeling. The marginal cost associated with the detection of additional cases using cfDNA was estimated from the difference in average costs divided by the difference in detection. The main factor was the unit cost of cfDNA testing. For example, replacing a combined test costing $150 with 3% false-positive rate and invasive testing at $1000, by cfDNA tests at $2000, $1500, $1000, and $500, the marginal cost is $8.0, $5.8, $3.6, and $1.4m, respectively. Costs were lower when replacing a quadruple test and higher for a 5% false-positive rate, but the relative importance of cfDNA unit cost was unchanged. A contingent policy whereby 10% to 20% women were selected for cfDNA testing by conventional screening was considerably more cost-efficient. Costs were sensitive to cfDNA uptake. Universal cfDNA screening for Down syndrome will only become affordable by public health purchasers if costs fall substantially. Until this happens, the contingent use of cfDNA is recommended. © 2013 John Wiley & Sons, Ltd.

Cross-calibration of Fuji TR image plate and RAR 2492 x-ray film to determine the response of a DITABIS Super Micron image plate scanner

NASA Astrophysics Data System (ADS)

Dunham, G.; Harding, E. C.; Loisel, G. P.; Lake, P. W.; Nielsen-Weber, L. B.

2016-11-01

Fuji TR image plate is frequently used as a replacement detector medium for x-ray imaging and spectroscopy diagnostics at NIF, Omega, and Z facilities. However, the familiar Fuji BAS line of image plate scanners is no longer supported by the industry, and so a replacement scanning system is needed. While the General Electric Typhoon line of scanners could replace the Fuji systems, the shift away from photo stimulated luminescence units to 16-bit grayscale Tag Image File Format (TIFF) leaves a discontinuity when comparing data collected from both systems. For the purposes of quantitative spectroscopy, a known unit of intensity applied to the grayscale values of the TIFF is needed. The DITABIS Super Micron image plate scanning system was tested and shown to potentially rival the resolution and dynamic range of Kodak RAR 2492 x-ray film. However, the absolute sensitivity of the scanner is unknown. In this work, a methodology to cross calibrate Fuji TR image plate and the absolutely calibrated Kodak RAR 2492 x-ray film is presented. Details of the experimental configurations used are included. An energy dependent scale factor to convert Fuji TR IP scanned on a DITABIS Super Micron scanner from 16-bit grayscale TIFF to intensity units (i.e., photons per square micron) is discussed.

Cross-calibration of Fuji TR image plate and RAR 2492 x-ray film to determine the response of a DITABIS Super Micron image plate scanner

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dunham, G., E-mail: gsdunha@sandia.gov; Harding, E. C.; Loisel, G. P.

Fuji TR image plate is frequently used as a replacement detector medium for x-ray imaging and spectroscopy diagnostics at NIF, Omega, and Z facilities. However, the familiar Fuji BAS line of image plate scanners is no longer supported by the industry, and so a replacement scanning system is needed. While the General Electric Typhoon line of scanners could replace the Fuji systems, the shift away from photo stimulated luminescence units to 16-bit grayscale Tag Image File Format (TIFF) leaves a discontinuity when comparing data collected from both systems. For the purposes of quantitative spectroscopy, a known unit of intensity appliedmore » to the grayscale values of the TIFF is needed. The DITABIS Super Micron image plate scanning system was tested and shown to potentially rival the resolution and dynamic range of Kodak RAR 2492 x-ray film. However, the absolute sensitivity of the scanner is unknown. In this work, a methodology to cross calibrate Fuji TR image plate and the absolutely calibrated Kodak RAR 2492 x-ray film is presented. Details of the experimental configurations used are included. An energy dependent scale factor to convert Fuji TR IP scanned on a DITABIS Super Micron scanner from 16-bit grayscale TIFF to intensity units (i.e., photons per square micron) is discussed.« less

Authentic Science in Education: Studies in Course-Based Research at the United States Military Academy

ERIC Educational Resources Information Center

Chase, Anthony M.

2016-01-01

This dissertation consists of two studies at the United States Military Academy. Both studies involve the use of Course-based Undergraduate Research Experiences (CUREs). These experiences give students the ability to engage in undergraduate research at an early point in their academic career by replacing traditional laboratory activities with…

Comparison of cropland and forest surface temperatures across the conterminous United States

Treesearch

James D. Wickham; Timothy G. Wade; Kurt H. Riitters

2012-01-01

Global climate models (GCM) investigating the effects of land cover on climate have found that replacing extra-tropical forest with cropland promotes cooling. We compared cropland and forest surface temperatures across the continental United States in 16 cells that were approximately 1◦ × 2◦ using 1 km2 MODIS land surface...

The Joint Operating Agreement: A Marvelous Machine with Damned Tight Steering.

ERIC Educational Resources Information Center

Pilgrim, Tim A.; Simpson, Roger

The Newspaper Preservation Act of 1970 is frequently viewed as a legislative device for averting the failure of a competing metropolitan daily newspaper and is said to create, for the formerly competing newspapers, a monolithic management unit which enjoys advantages over the two publishing units it replaces. A study examined one of those…

75 FR 2055 - Airworthiness Directives; Fokker Services B.V. Model F.28 Mark 0070 and 0100 Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-14

... include inspecting the backlash remover of the elevator booster control unit to determine the displacement... measurement of the displacement, the compliance time for replacement ranges from before further flight to 3... of the elevator booster control unit to determine the displacement of the pivot bolt; and if...

Health Service Inpatient Units for People with Intellectual Disabilities and Challenging Behaviour or Mental Health Problems

ERIC Educational Resources Information Center

Mansell, Jim; Ritchie, Fiona; Dyer, Ricinda

2010-01-01

Background: As institutions for people with intellectual disabilities have been replaced with community services, health care provision has developed to provide assessment and treatment, low and medium secure units for people with challenging behaviour or mental health problems. These include both public and private sector provision. Little is…

40 CFR 96.71 - Initial certification and recertification procedures

Code of Federal Regulations, 2010 CFR

2010-07-01

...: replacement of the analyzer, change in location or orientation of the sampling probe or site, or changing of... basis under § 96.74(d); (i) For a unit that has commences operation before its compliance deadline under... control period basis under § 96.74(b)(3)(ii) of this part: (i) For a unit that commenced operation before...

Quantifying the multi-scale response of avifauna to prescribed fire experiments in the southwest United States

Treesearch

Brett G. Dickson; Barry R. Noon; Curtis H. Flather; Stephanie Jentsch; William M. Block

2009-01-01

Landscape-scale disturbance events, including ecological restoration and fuel reduction activities, can modify habitat and affect relationships between species and their environment. To reduce the risk of uncharacteristic stand-replacing fires in the southwestern United States, land managers are implementing restoration and fuels treatments (e.g., mechanical thinning,...

Hadfield and Marshburn during HRCS Ku Comm Unit 2 Installation

NASA Image and Video Library

2013-04-02

ISS035-E-013783 (2 April 2013) --- In the U.S. lab Destiny on the International Space Station, Expedition 35 Commander Chris Hadfield (right) and Flight Engineer Tom Marshburn remove the Video Baseband Signal Processor (VBSP) in order to replace it with a new Ku communication unit and its associated data and Ethernet cabling.

Hadfield and Marshburn during HRCS Ku Comm Unit 2 Installation

NASA Image and Video Library

2013-04-02

ISS035-E-013790 (2 April 2013) --- In the U.S. lab Destiny on the International Space Station, Expedition 35 Commander Chris Hadfield (background) and Flight Engineer Tom Marshburn remove the Video Baseband Signal Processor (VBSP) in order to replace it with a new Ku communication unit and its associated data and Ethernet cabling.

3D vision upgrade kit for TALON robot

NASA Astrophysics Data System (ADS)

Edmondson, Richard; Vaden, Justin; Hyatt, Brian; Morris, James; Pezzaniti, J. Larry; Chenault, David B.; Tchon, Joe; Barnidge, Tracy; Kaufman, Seth; Pettijohn, Brad

2010-04-01

In this paper, we report on the development of a 3D vision field upgrade kit for TALON robot consisting of a replacement flat panel stereoscopic display, and multiple stereo camera systems. An assessment of the system's use for robotic driving, manipulation, and surveillance operations was conducted. The 3D vision system was integrated onto a TALON IV Robot and Operator Control Unit (OCU) such that stock components could be electrically disconnected and removed, and upgrade components coupled directly to the mounting and electrical connections. A replacement display, replacement mast camera with zoom, auto-focus, and variable convergence, and a replacement gripper camera with fixed focus and zoom comprise the upgrade kit. The stereo mast camera allows for improved driving and situational awareness as well as scene survey. The stereo gripper camera allows for improved manipulation in typical TALON missions.

Trends in Educational Attainment by Race/Ethnicity, Nativity, and Sex in the United States, 1989–2005

PubMed Central

EVERETT, BETHANY G.; ROGERS, RICHARD G.; HUMMER, ROBERT A.; KRUEGER, PATRICK M.

2012-01-01

Despite the importance of education for shaping individuals’ life chances, little research has examined trends and differences in educational attainment for detailed demographic subpopulations in the United States. We use labor market segmentation and cohort replacement theories, linear regression methods, and data from the National Health Interview Survey to understand educational attainment by race/ethnicity, nativity, birth cohort, and sex between 1989 and 2005 in the United States. There have been significant changes in educational attainment over time. In support of the cohort replacement theory, we find that across cohorts, females have enjoyed greater gains in education than men, and for some race/ethnic groups, recent cohorts of women average more years of education than comparable men. And in support of labor market segmentation theories, foreign-born Mexican Americans continue to possess relatively low levels of educational attainment. Our results can aid policymakers in identifying vulnerable populations, and form the base from which to better understand changing disparities in education. PMID:22649275

Flywheel Energy Storage System Designed for the International Space Station

NASA Technical Reports Server (NTRS)

Delventhal, Rex A.

2002-01-01

Following successful operation of a developmental flywheel energy storage system in fiscal year 2000, researchers at the NASA Glenn Research Center began developing a flight design of a flywheel system for the International Space Station (ISS). In such an application, a two-flywheel system can replace one of the nickel-hydrogen battery strings in the ISS power system. The development unit, sized at approximately one-eighth the size needed for ISS was run at 60,000 rpm. The design point for the flight unit is a larger composite flywheel, approximately 17 in. long and 13 in. in diameter, running at 53,000 rpm when fully charged. A single flywheel system stores 2.8 kW-hr of useable energy, enough to light a 100-W light bulb for over 24 hr. When housed in an ISS orbital replacement unit, the flywheel would provide energy storage with approximately 3 times the service life of the nickel-hydrogen battery currently in use.

Installation of new Generation General Purpose Computer (GPC) compact unit

NASA Technical Reports Server (NTRS)

1991-01-01

In the Kennedy Space Center's (KSC's) Orbiter Processing Facility (OPF) high bay 2, Spacecraft Electronics technician Ed Carter (right), wearing clean suit, prepares for (26864) and installs (26865) the new Generation General Purpose Computer (GPC) compact IBM unit in Atlantis', Orbiter Vehicle (OV) 104's, middeck avionics bay as Orbiter Systems Quality Control technician Doug Snider looks on. Both men work for NASA contractor Lockheed Space Operations Company. All three orbiters are being outfitted with the compact IBM unit, which replaces a two-unit earlier generation computer.

Oxygen enhanced switching to combustion of lower rank fuels

DOEpatents

Kobayashi, Hisashi; Bool, III, Lawrence E.; Wu, Kuang Tsai

2004-03-02

A furnace that combusts fuel, such as coal, of a given minimum energy content to obtain a stated minimum amount of energy per unit of time is enabled to combust fuel having a lower energy content, while still obtaining at least the stated minimum energy generation rate, by replacing a small amount of the combustion air fed to the furnace by oxygen. The replacement of oxygen for combustion air also provides reduction in the generation of NOx.

Welfare: Reform or Replacement? (Child Support Enforcement---II). Hearing before the Subcommittee on Social Security and Family Policy of the Committee on Finance. United States Senate, One Hundredth Congress, First Session.

ERIC Educational Resources Information Center

Congress of the U.S., Washington, DC. Senate Committee on Finance.

This transcript is from the third in a series of hearings before the Senate Subcommittee on Social Security and Family Policy focusing on whether the present welfare system should be reformed or replaced. A series of public officials, child and family advocates, and other interested parties testified on the issue of enforcement of child support…

Conceptual design of 100 TW solid state laser system

DOE Office of Scientific and Technical Information (OSTI.GOV)

McMordie, J.A.

1995-12-31

Currently the main solid state laser facilities used for plasma physics research in the United Kingdom are the VULCAN laser at the Rutherford Appleton Laboratory and the HELEN facility at the Atomic Weapons Establishment. In the future it is proposed to replace HELEN with a new 100 TW facility to come on line early in the next century. A brief review is given of the VULCAN and HELEN. Then the authors discuss the design for the HELEN replacement.

[Mobile single-pass batch hemodialysis system in intensive care medicine. Reduction of costs and workload in renal replacement therapy].

PubMed

Hopf, H-B; Hochscherf, M; Jehmlich, M; Leischik, M; Ritter, J

2007-07-01

This paper describes the introduction of a single-pass batch hemodialysis system for renal replacement therapy in a 14 bed intensive care unit. The goals were to reduce the workload of intensive care unit physicians using an alternative and simpler method compared to continuous veno-venous hemodiafiltration (CVVHDF) and to reduce the costs of hemofiltrate solutions (80,650 EUR per year in our clinic in 2005). We describe and evaluate the process of implementation of the system as well as the achieved and prospective savings. We conclude that a close cooperation of all participants (physicians, nurses, economists, technicians) of a hospital can achieve substantial benefits for patients and employees as well as reduce the economic burden of a hospital.

HiL simulation in biomechanics: a new approach for testing total joint replacements.

PubMed

Herrmann, Sven; Kaehler, Michael; Souffrant, Robert; Rachholz, Roman; Zierath, János; Kluess, Daniel; Mittelmeier, Wolfram; Woernle, Christoph; Bader, Rainer

2012-02-01

Instability of artificial joints is still one of the most prevalent reasons for revision surgery caused by various influencing factors. In order to investigate instability mechanisms such as dislocation under reproducible, physiologically realistic boundary conditions, a novel test approach is introduced by means of a hardware-in-the-loop (HiL) simulation involving a highly flexible mechatronic test system. In this work, the underlying concept and implementation of all required units is presented enabling comparable investigations of different total hip and knee replacements, respectively. The HiL joint simulator consists of two units: a physical setup composed of a six-axes industrial robot and a numerical multibody model running in real-time. Within the multibody model, the anatomical environment of the considered joint is represented such that the soft tissue response is accounted for during an instability event. Hence, the robot loads and moves the real implant components according to the information provided by the multibody model while transferring back the position and resisting moment recorded. Functionality of the simulator is proved by testing the underlying control principles, and verified by reproducing the dislocation process of a standard total hip replacement. HiL simulations provide a new biomechanical testing tool for analyzing different joint replacement systems with respect to their instability behavior under realistic movements and physiological load conditions. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

A review of alternatives to di (2-ethylhexyl) phthalate-containing medical devices in the neonatal intensive care unit

PubMed Central

Van Vliet, EDS; Reitano, EM; Chhabra, JS; Bergen, GP; Whyatt, RM

2012-01-01

Objective To conduct an extensive literature and toxicological database review on substitute compounds and available alternative medical products to replace polyvinyl chloride (PVC) and/or di(2-ethylhexyl) phthalate (DEHP), and conduct a DEHP-medical inventory analysis at a large metropolitan neonatal intensive care unit (NICU). Study Design A systematic search for DEHP-free alternative products was performed using online databases. An informal audit of a large metropolitan NICU was undertaken in 2005 and 2006; 21 products were identified that could potentially contain DEHP. Availability of DEHP-free alternatives was determined through company websites and phone interviews. Result Two alternative approaches are available for replacing DEHP in NICU medical products: (1) replacement by DEHP-free plasticizers; and (2) replacement of PVC entirely through the use of other polymers. Both approaches seem to provide less harmful substitutes to DEHP, but support PVC-free polymers as the preferred alternative. However, significant data gaps exist, particularly for the alternative polymers. In all, 10 out of 21 (48%) products in the NICU audit were DEHP-free; six consisted of alternative polymers and four of alternative plasticizers. Of the remaining 11 products, only three were available without DEHP at the time of the audit. Conclusion Because of significant data gaps, systematic toxicological testing of DEHP-free alternatives is imperative. Continued development of alternative products is also needed. PMID:21311501

A System Approach to Navy Medical Education and Training. Appendix 24. Equipment Repair Technician.

DTIC Science & Technology

1974-08-31

DENTAL SYRINGE 40 lCORRECT MALFUNCTIONING RETRACTION MECHANISM ON DENTAL UNIT 41 1ADJUST DRIP RATE ON AIR-DRIVEN DENTAL HANDPIECE 42 ICLEAN VALVE... DENTAL UNIT 46 CLEAN/REPLACE WATER FILTER ELEMENTS ON DENTAL UNIT 47 ICLEAR WATER LINES ON CONTRA-ANGLE AIR-DRIVEN DENTAL HANDPIECE 48 IREPLACE WORN...GASKETS ON AIR-DRIVEN DENTAL HANDPIECE 49 IADJUST END PLAY ON DENTAL HANOPIECE so ICLEAN AND REASSEMBLE BELT-DRIVEN DENTAL HANDPIECE TURN

Development of Protection and Control Unit for Distribution Substation

NASA Astrophysics Data System (ADS)

Iguchi, Fumiaki; Hayashi, Hideyuki; Takeuchi, Motohiro; Kido, Mitsuyasu; Kobayashi, Takashi; Yanaoka, Atsushi

The Recently, electronics and IT technologies have been rapidly innovated and have been introduced to power system protection & control system to achieve high reliability, maintainability and more functionality. Concerning the distribution substation application, digital relays have been applied for more than 10 years. Because of a number of electronic devices used for it, product cost becomes higher. Also, products installed during the past high-growth period will be at the end of lifetime and will be replaced. Therefore, replacing market is expected to grow and the reduction of cost is demanded. Considering above mentioned background, second generation digital protection and control unit as a successor is designed to have following concepts. Functional integration based on advanced digital technologies, Ethernet LAN based indoor communication network, cost reduction and downsizing. Pondering above concepts, integration of protection and control function is adopted in contrary to the functional segregation applied to the previous system in order to achieve one-unit concept. Also the adoption of Ethernet LAN for inter-unit communication is objective. This report shows the development of second-generation digital relay for distribution substation, which is equipped with control function and Ethernet LAN by reducing the size of auxiliary transformer unit and the same size as previous product is realized.

Conformational analysis of (1. -->. 4)-. beta. -D-mannan triacetate

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deslandes, Y.; Marchessault, R.H.; Bluhm, T.L.

1983-01-01

In wood, algae, and tubers, glucomannans have varying mannose-to-glucose ratios (M/G). Since diffraction on glucomannans of widely varying M/G do not show significant change in unit-cell base plane dimensions, the authors have suggested that isomorphous replacement may occur in glucomannans. To further investigate this point, it has been undertaken conformational analysis of glucomannan triacetate in which the X-ray fiber diagram suggests that two nonequivalent residues make up the asymmetric unit. X-ray fiber diagrams of the triacetate of glucomannan from Tubera salep show twofold symmetry along the chain axis with a fiber repeat of 1.6 nm. This implies that the asymmetricmore » unit is composed of two pyranose rings since the virtual bond length of a single pyranose ring cannot be greater than approximately 0.54 nm. By using empirical potential functions, it could be shown that the minimum internal energy of a mannan triacetate chain corresponds to a state where contiguous mannose triacetate units are not conformationally equivalent. This supports the hypothesis of mannobiose hexaacetate as the asymmetric unit. Furthermore, introduction of glucose triacetate into the backbone did not change the minimum energy conformation, thereby lending support to the isomorphous replacement concept in crystalline glucomannans. 19 references, 13 figures, 2 tables.« less

Case study involving suctioning of an electromyographic endotracheal tube.

PubMed

Evanina, Eileen Youshock; Hanisak, Jill L

2005-04-01

The electromyographic endotracheal tube (EMG-ETT) is a relatively new tool used to measure integrity of the vocal cord structures during surgery. We describe a case in which an EMG-ETT was inserted for the operative period but not replaced with an ETT during the immediate postoperative period. Intensive care unit nurses had difficulty suctioning the EMG-ETT. The patient was not provided the pulmonary toilet necessary until the EMG-ETT was removed and replaced with a regular ETT. The purpose of this article is to make anesthesia providers aware that when mechanical ventilation is required during the postoperative period, the EMG-ETT should be removed and replaced with a regular ETT to facilitate pulmonary toilet.

TAVR and SAVR: Current Treatment of Aortic Stenosis.

PubMed

Hu, Patrick P

2012-01-01

Transcatheter aortic valve replacement (TAVR) was approved in the United States in late 2011, providing a critically needed alternative therapy for patients with severe aortic stenosis previously refused surgical aortic valve replacement (SAVR). Over 20,000 TAVR have been performed in patients worldwide since 2002 when Alain Cribier performed the first-in-man TAVR. This paper reviews the data from balloon expandable and self-expanding aortic stent valves as well as data comparing them with traditional surgical aortic valve replacement (SAVR). Complications using criteria established by the Valve Academic Research Consortium (VARC) are reviewed. Future challenges and possibilities are discussed and will make optimizing TAVR an important goal in the years to come.

TAVR and SAVR: Current Treatment of Aortic Stenosis

PubMed Central

Hu, Patrick P.

2012-01-01

Transcatheter aortic valve replacement (TAVR) was approved in the United States in late 2011, providing a critically needed alternative therapy for patients with severe aortic stenosis previously refused surgical aortic valve replacement (SAVR). Over 20,000 TAVR have been performed in patients worldwide since 2002 when Alain Cribier performed the first-in-man TAVR. This paper reviews the data from balloon expandable and self-expanding aortic stent valves as well as data comparing them with traditional surgical aortic valve replacement (SAVR). Complications using criteria established by the Valve Academic Research Consortium (VARC) are reviewed. Future challenges and possibilities are discussed and will make optimizing TAVR an important goal in the years to come. PMID:22952419

49 CFR Appendix B to Part 564 - Information To Be Submitted for Long Life Replaceable Light Sources of Limited Definition

Code of Federal Regulations, 2010 CFR

2010-10-01

... light sources used in motor vehicle headlighting systems. This part also serves as a repository for... standardized sealed beam units used in motor vehicle headlighting systems. § 564.2 Purposes. The purposes of... manufacturing specifications of standardized sealed beam headlamp units used on motor vehicles so that all...

An Assessment of the Red Maple Resource in the Northeastern United States

Treesearch

Delton R., Jr. Alderman; Matthew S. Bumgardner; John E. Baumgras; John E. Baumgras

2005-01-01

The red maple resource in the northeastern United States has exhibited dramatic gains in the past 3 decades in terms of stem numbers and net volume. Growing stock and sawtimber volumes have displayed extraordinary growth compared to other species, and red maple is replacing important market species that have historically been used in the Northeast. The increase in red...

40 CFR 81.329 - Nevada.

Code of Federal Regulations, 2010 CFR

2010-07-01

... on the State of Nevada Division of Water Resources' map titled Water Resources and Inter-basin Flows...-26E) X Clovers Area (64)(32-39N, 42-46E) X 1 EPA designation replaces State designation. 2 Rest of... Boulder Flat (61) (31-37N, 45-51E): Upper Unit 61 X Lower Unit 61 X Rest of State 1 X 1 Rest of State...

Feasibility of a Student Unit Record System within the Integrated Postsecondary Education Data System. Research and Development Report. NCES 2005-160

ERIC Educational Resources Information Center

Cunningham, Alisa F.; Milam, John

2005-01-01

This report examines the feasibility of implementing a student unit record system to replace the student-related components that currently are based on aggregate institution-level data collected as part of the Integrated Postsecondary Education Data System (IPEDS). The feasibility study was initiated by the National Center for Education Statistics…

Africanization in the United States: replacement of feral European honeybees (Apis mellifera L.) by an African hybrid swarm.

PubMed

Pinto, M Alice; Rubink, William L; Patton, John C; Coulson, Robert N; Johnston, J Spencer

2005-08-01

The expansion of Africanized honeybees from South America to the southwestern United States in <50 years is considered one of the most spectacular biological invasions yet documented. In the American tropics, it has been shown that during their expansion Africanized honeybees have low levels of introgressed alleles from resident European populations. In the United States, it has been speculated, but not shown, that Africanized honeybees would hybridize extensively with European honeybees. Here we report a continuous 11-year study investigating temporal changes in the genetic structure of a feral population from the southern United States undergoing Africanization. Our microsatellite data showed that (1) the process of Africanization involved both maternal and paternal bidirectional gene flow between European and Africanized honeybees and (2) the panmitic European population was replaced by panmitic mixtures of A. m. scutellata and European genes within 5 years after Africanization. The post-Africanization gene pool (1998-2001) was composed of a diverse array of recombinant classes with a substantial European genetic contribution (mean 25-37%). Therefore, the resulting feral honeybee population of south Texas was best viewed as a hybrid swarm.

Decreasing Postanesthesia Care Unit to Floor Transfer Times to Facilitate Short Stay Total Joint Replacements.

PubMed

Sibia, Udai S; Grover, Jennifer; Turcotte, Justin J; Seanger, Michelle L; England, Kimberly A; King, Jennifer L; King, Paul J

2018-04-01

We describe a process for studying and improving baseline postanesthesia care unit (PACU)-to-floor transfer times after total joint replacements. Quality improvement project using lean methodology. Phase I of the investigational process involved collection of baseline data. Phase II involved developing targeted solutions to improve throughput. Phase III involved measured project sustainability. Phase I investigations revealed that patients spent an additional 62 minutes waiting in the PACU after being designated ready for transfer. Five to 16 telephone calls were needed between the PACU and the unit to facilitate each patient transfer. The most common reason for delay was unavailability of the unit nurse who was attending to another patient (58%). Phase II interventions resulted in transfer times decreasing to 13 minutes (79% reduction, P < .001). Phase III recorded sustained transfer times at 30 minutes, a net 52% reduction (P < .001) from baseline. Lean methodology resulted in the immediate decrease of PACU-to-floor transfer times by 79%, with a 52% sustained improvement. Our methods can also be used to improve efficiencies of care at other institutions. Copyright © 2016 American Society of PeriAnesthesia Nurses. Published by Elsevier Inc. All rights reserved.

Reducing saturated fat with oleogel/shortening blends in a baked product.

PubMed

Mert, Behic; Demirkesen, Ilkem

2016-05-15

Short dough cookie structure, characterized by its aerated and tender texture, depends on the presence of solid fat during kneading. The objective of this study was to investigate the potential application of Candelilla wax (CDW) containing oleogels for partial replacement of the shortening in cookies. Oleogels were prepared with different amounts of CDW and blended with a commercial bakery shortening. After crystallizing the oleogel/shortening blends by using a pilot scale crystallization unit, the blends were evaluated in a cookie formulations. When the shortening was completely replaced with oleogel softer products were obtained compared to liquid oil, but they were harder than the shortening containing products. On the other hand, partial replacement of shortening with oleogels provided much more acceptable dough and cookie characteristics. Results suggest that gradual replacement of shortening with oleogels may be a suitable approach for reduction of saturated fat in short dough products. Copyright © 2015 Elsevier Ltd. All rights reserved.

Enhanced operator perception through 3D vision and haptic feedback

NASA Astrophysics Data System (ADS)

Edmondson, Richard; Light, Kenneth; Bodenhamer, Andrew; Bosscher, Paul; Wilkinson, Loren

2012-06-01

Polaris Sensor Technologies (PST) has developed a stereo vision upgrade kit for TALON® robot systems comprised of a replacement gripper camera and a replacement mast zoom camera on the robot, and a replacement display in the Operator Control Unit (OCU). Harris Corporation has developed a haptic manipulation upgrade for TALON® robot systems comprised of a replacement arm and gripper and an OCU that provides haptic (force) feedback. PST and Harris have recently collaborated to integrate the 3D vision system with the haptic manipulation system. In multiple studies done at Fort Leonard Wood, Missouri it has been shown that 3D vision and haptics provide more intuitive perception of complicated scenery and improved robot arm control, allowing for improved mission performance and the potential for reduced time on target. This paper discusses the potential benefits of these enhancements to robotic systems used for the domestic homeland security mission.

DOE Office of Scientific and Technical Information (OSTI.GOV)

J. E. Lawson, R. Marsala, S. Ramakrishnan, X. Zhao, P. Sichta

In order to provide improved and expanded experimental capabilities, the existing Transrex power supplies at PPPL are to be upgraded and modernized. Each of the 39 power supplies consists of two six pulse silicon controlled rectifier sections forming a twelve pulse power supply. The first modification is to split each supply into two independent six pulse supplies by replacing the existing obsolete twelve pulse firing generator with two commercially available six pulse firing generators. The second change replaces the existing control link with a faster system, with greater capacity, which will allow for independent control of all 78 power supplymore » sections. The third change replaces the existing Computer Automated Measurement and Control (CAMAC) based fault detector with an Experimental Physics and Industrial Control System (EPICS) compatible unit, eliminating the obsolete CAMAC modules. Finally the remaining relay logic and interfaces to the "Hardwired Control System" will be replaces with a Programmable Logic Controller (PLC).« less

Features of electric drive sucker rod pumps for oil production

NASA Astrophysics Data System (ADS)

Gizatullin, F. A.; Khakimyanov, M. I.; Khusainov, F. F.

2018-01-01

This article is about modes of operation of electric drives of downhole sucker rod pumps. Downhole oil production processes are very energy intensive. Oil fields contain many oil wells; many of them operate in inefficient modes with significant additional losses. Authors propose technical solutions to improve energy performance of a pump unit drives: counterweight balancing, reducing of electric motor power, replacing induction motors with permanent magnet motors, replacing balancer drives with chain drives, using of variable frequency drives.

Investigation into the High Voltage Shutdown of the Oxygen Generator System in the International Space Station

NASA Technical Reports Server (NTRS)

Carpenter, Joyce E.; Gentry, Gregory J.; Diderich, Greg S.; Roy, Robert J.; Golden, John L.; VanKeuren, Steve; Steele, John W.; Rector, Tony J.; Varsik, Jerome D.; Montefusco, Daniel J.;

STS-109 MS Newman and Massimino in airlock after EVA

NASA Image and Video Library

2002-03-05

STS109-326-031 (5 March 2002) --- The broad smiles of astronauts Michael J. Massimino (left) and James H. Newman reflect the success of their just-completed lengthy space walk designed to finish the replacement of the solar arrays on the Hubble Space Telescope (HST). A day earlier, two other astronauts replaced one of sets of solar panels. The two are in the process of doffing their extravehicular mobility unit (EMU) space suits on the mid deck of the Space Shuttle Columbia.

Astronauts Hoffman and Musgrave replace Solar Array Drive Electronics

NASA Image and Video Library

1993-12-09

STS061-102-010 (9 Dec 1993) --- Astronauts Jeffrey A. Hoffman (left) and F. Story Musgrave team to replace one of two Solar Array Drive Electronics (SADE) units on the Hubble Space Telescope (HST). Musgrave is standing on a foot restraint mounted on the end of the Space Shuttle Endeavour's Remote Manipulator System (RMS) arm. The black object, in upper left corner, is part of the window frame, through which this 70mm frame was exposed, inside Endeavour's cabin.

ASC Addresses Unit Commanders’ Concerns through LBE and Reset Programs

DTIC Science & Technology

2008-09-01

Distribution Management Center (DMC). The DMC, based at ASC Headquarters on Rock Island Arsenal, Ilinois, has become the single ASC integrator for LBE and field-level reset in support of ARFORGEN. The reset of units returning from OEF/OIF consists of a series of actions to restore the units to a desired level of combat capability commensurate with future mission requirements. These actions include the repair of equipment, replacement of equipment lost during operations, and recapitalization of equipment where feasible and

Antidumping Action in the United States and Around the World: An Analysis of International Data. CBO Paper.

DTIC Science & Technology

1998-06-01

the price of sugar to the point that some processors, such as soft-drink producers, have replaced it with high - fructose corn syrup . That example...United States, both one on one and in the aggregate. Antidumping duty rates are high enough to be significant impediments to trade, especially the duties...the United States, although their rates are still high enough to be significant impediments to trade. Among the most active users, Canada had the next

Collective Training and Fielding Opportunities for the Objective Force Maneuver Systems at the Unit of Action Level in a Unit Manning/Unit Replacement Personnel System

DTIC Science & Technology

2003-04-07

PERSON Rife, Dave RifeD@awc.carlisle.army.mil a. REPORT Unclassified b. ABSTRACT Unclassified c. THIS PAGE Unclassified 19b. TELEPHONE NUMBER International...38 WORD COUNT = 8975 39 40 ENDNOTES 1 COL Pete Zielinski , Director, Joint/Army concepts HQs TRADOC “Transformation Update” briefing slide #9, Briefing...Staff. Interviewed by author, 18 February 2003, Carlisle Barracks, PA. Zielinski , Pete, COL Director, Joint/Army concepts HQs TRADOC “Transformation

Azelastine Nasal Spray

MedlinePlus

... use more or less of it or use it more often than prescribed by your doctor.Before using azelastine for the first time, remove the child-resistant screw cap and replace with the pump unit. Prime ...

Cost of acute renal replacement therapy in the intensive care unit: results from The Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Study

PubMed Central

2010-01-01

Introduction Severe acute kidney injury (AKI) can be treated with either continuous renal replacement therapy (CRRT) or intermittent renal replacement therapy (IRRT). Limited evidence from existing studies does not support an outcome advantage of one modality versus the other, and most centers around the word use both modalities according to patient needs. However, cost estimates involve multiple factors that may not be generalizable to other sites, and, to date, only single-center cost studies have been performed. The aim of this study was to estimate the cost difference between CRRT and IRRT in the intensive care unit (ICU). Methods We performed a post hoc analysis of a prospective observational study among 53 centers from 23 countries, from September 2000 to December 2001. We estimated costs based on staffing, as well as dialysate and replacement fluid, anticoagulation and extracorporeal circuit. Results We found that the theoretic range of costs were from $3,629.80/day more with CRRT to $378.60/day more with IRRT. The median difference in cost between CRRT and IRRT was $289.60 (IQR 830.8-116.8) per day (greater with CRRT). Costs also varied greatly by region. Reducing replacement fluid volumes in CRRT to ≤ 25 ml/min (approximately 25 ml/kg/hr) would result in $67.20/day (23.2%) mean savings. Conclusions Cost considerations with RRT are important and vary substantially among centers. We identified the relative impact of four cost domains (nurse staffing, fluid, anticoagulation, and extracorporeal circuit) on overall cost differences, and hospitals can look to these areas to reduce costs associated with RRT. PMID:20346163

Bridge condition assessment using remote sensors.

DOT National Transportation Integrated Search

2013-02-01

The challenges of a deteriorating and aged infrastructure continue to challenge transportation : authorities as they align maintenance and replacement priorities with decreasing funds. The : United States is home to nearly 600,000 highway bridges of ...

Liquid cooled garments

NASA Technical Reports Server (NTRS)

1975-01-01

Liquid cooled garments employed in several applications in which severe heat is encountered are discussed. In particular, the use of the garments to replace air line cooling units in a variety of industrial processing situations is discussed.

24 CFR 585.310 - Project-related restrictions applicable to Youthbuild transitional housing for the homeless.

Code of Federal Regulations, 2010 CFR

2010-04-01

... implementation grant includes the eligible activities of acquisition, architectural and engineering fees, construction, rehabilitation, operating costs or replacement reserves of transitional housing units, and where...

KSC-97pc655

NASA Image and Video Library

1997-04-16

An oxygen generator destined to replace a malfunctioning unit on the Russian Mir Space Station is the object of much curiosity during preflight preparations in the SPACEHAB Payload Processing Facility. A SPACEHAB Double Module on the Space Shuttle Atlantis will carry the oxygen generator to Mir during STS-84, the sixth Shuttle-Mir docking. The nearly 300-pound generator, manufactured by RSC Energia in Russia, will replace one of two Mir units that have been malfunctioning recently. The generator functions by electrolysis, which separates water into its oxygen and hydrogen components. The hydrogen is vented and the oxygen is used for breathing by the Mir crew. The generator is 4.2 feet in length and 1.4 feet in diameter. STS-84, which is planned to include a Mir crew exchange of astronaut C. Michael Foale for Jerry M. Linenger, is targeted for a May 15 liftoff

A new approach to explore the binding space of polysaccharide-based ligands: selectin antagonists.

PubMed

Calosso, Mickael; Charpentier, Daniel; Vaillancourt, Marc; Bencheqroun, Mohammed; St-Pierre, Gabrielle; Wilkes, Brian C; Guindon, Yvan

2012-12-13

The discovery of molecules that interfere with the binding of a ligand to a receptor remains a topic of great interest in medicinal chemistry. Herein, we report that a monosaccharide unit of a polysaccharide ligand can be replaced advantageously by a conformationally locked acyclic molecular entity. A cyclic component of the selectin ligand Sialyl Lewis(x), GlcNAc, is replaced by an acyclic tether, tartaric esters, which link two saccharide units. The conformational bias of this acyclic tether originates from the minimization of intramolecular dipole-dipole interaction and the gauche effect. The evaluation of the binding of these derivatives to P-selectin was measured by surface plasmon resonance spectroscopy. The results obtained in our pilot study suggest that the discovery of tunable tethers could facilitate the exploration of the carbohydrate recognition domain of various receptors.

Assessing the guidelines for potassium replacement in pediatric oncology patients receiving amphotericin B.

PubMed

Lafreniere, Janet A; Hamilton, Donald P; Carr, Roxane R

2006-10-01

To examine the practice of potassium chloride (KCl) replacement in pediatric oncology patients receiving amphotericin B (amp-B). A retrospective observational chart review was conducted of patients who received amp-B on the oncology unit between August 2000 and May 2001. A survey was distributed to pediatric oncology pharmacists at other pediatric institutions to assess KCl infusion guidelines across North America. Twenty hypokalemic episodes were identified within 22 patient admissions. Fifty-five percent used KCl replacement (by all combined routes) at rates exceeding the institution's guidelines. Other pediatric institutions varied with respect to the maximum rates and concentration of KCl permitted on non-intensive care units. Based on the data from this review, the KCl administration guidelines for our hospital were changed. We now allow a maximum peripheral line concentration of 60 mEq/L, a maximum central line concentration of 120 mEq/L and a maximum KCl infusion rate of 0.4 mEq/kg/hr without the requirement of a heart monitor. Parenteral Nutrition is now restricted to maximum potassium concentration of 80 mEq/L and fluid-restricted patients are restricted to a maximum concentration of 150 mEq/L.

A warm thermal enclave in the late Pleistocene of the south-eastern United States.

PubMed

Russell, Dale A; Rich, Fredrick J; Schneider, Vincent; Lynch-Stieglitz, Jean

2009-05-01

Physical and biological evidence supports the probable existence of an enclave of relatively warm climate located between the Southern Appalachian Mountains and the Atlantic Ocean in the United States during the Last Glacial Maximum. The region supported a mosaic of forest and prairie habitats inhabited by a "Floridian" ice-age biota. Plant and vertebrate remains suggest an ecological gradient towards Cape Hatteras (35 degreesN) wherein forests tended to replace prairies, and browsing proboscideans tended to replace grazing proboscideans. Beyond 35 degreesN, warm waters of the Gulf Stream were deflected towards the central Atlantic, and a cold-facies biota replaced "Floridian" biota on the Atlantic coastal plain. Because of niche diversity and relatively benign climate, biodiversity may have been greater in the south-eastern thermal enclave than in other unglaciated areas of North America. However, the impact of terminal Pleistocene megafaunal extinctions may also have been shorter and more severe in the enclave than further north. A comparison with biotic changes that occurred in North America approximately 55 million years (ma) ago at the Paleocene-Eocene Thermal Maximum suggests that similar processes of change took place under both ice-house and greenhouse climates.

Electric auxiliary power unit for Shuttle evolution

NASA Technical Reports Server (NTRS)

Meyer, Doug; Weber, Kent; Scott, Walter

1989-01-01

The Space Shuttle Orbiter currently uses three hydrazine fueled auxiliary power units (APUs) to provide hydraulic power for the vehicle aerodynamic surface controls, main engine thrust vector control, landing gear, steering, and brakes. Electric auxiliary power units have been proposed as possible replacements to the hydrazine auxiliary power units. Along with the potential advantages, this paper describes an Electric APU configuration and addresses the technical issues and risks associated with the subsystem components. Additionally, characteristics of an Electric APU compared to the existing APU and the direction of future study with respect to the Electric APU is suggested.

Biomimetic tissue-engineered anterior cruciate ligament replacement

PubMed Central

Cooper, James A.; Sahota, Janmeet S.; Gorum, W. Jay; Carter, Janell; Doty, Stephen B.; Laurencin, Cato T.

2007-01-01

There are >200,000 anterior cruciate ligament (ACL) ruptures each year in the United States, and, due to the poor healing properties of the ACL, surgical reconstruction with autograft or allograft tissue is the current treatment of these injuries. To regenerate the ACL, the ideal matrix should be biodegradable, porous, and exhibit sufficient mechanical strength to allow formation of neoligament tissue. Researchers have developed ACL scaffolds with collagen fibers, silk, biodegradable polymers, and composites with limited success. Our group has developed a biomimetic ligament replacement by using 3D braiding technology. In this preliminary in vivo rabbit model study for ACL reconstruction, the histological and mechanical evaluation demonstrated excellent healing and regeneration with our cell-seeded, tissue-engineered ligament replacement. PMID:17360607

Fracture strength of all-ceramic lithium disilicate and porcelain-fused-to-metal bridges for molar replacement after dynamic loading.

PubMed

Chitmongkolsuk, Somsak; Heydecke, Guido; Stappert, Christian; Strub, Joerg R

2002-03-01

The replacement of missing posterior teeth using all-ceramic bridges remains a challenge. This study compares the fracture resistance of all-ceramic 3-unit bridges for the replacement of first molars to conventional porcelain-fused-to-metal bridges. Human premolars and molars were used to create two test groups and one control group of 16 specimens each. To simulate clinical parameters, the specimens were exposed to cyclic fatigue loading in an artificial mouth with simultaneous thermocycling. All samples were thereafter exposed to fracture strength testing. Porcelain-fused-to-metal bridges showed significantly higher fracture strengths than all-ceramic bridges. However, the fracture strength of the all-ceramic bridges was higher than peak physiological chewing forces.

Enhanced recovery in total hip replacement: a clinical review.

PubMed

Ibrahim, M S; Twaij, H; Giebaly, D E; Nizam, I; Haddad, F S

2013-12-01

The outcome after total hip replacement has improved with the development of surgical techniques, better pain management and the introduction of enhanced recovery pathways. These pathways require a multidisciplinary team to manage pre-operative education, multimodal pain control and accelerated rehabilitation. The current economic climate and restricted budgets favour brief hospitalisation while minimising costs. This has put considerable pressure on hospitals to combine excellent results, early functional recovery and shorter admissions. In this review we present an evidence-based summary of some common interventions and methods, including pre-operative patient education, pre-emptive analgesia, local infiltration analgesia, pre-operative nutrition, the use of pulsed electromagnetic fields, peri-operative rehabilitation, wound dressings, different surgical techniques, minimally invasive surgery and fast-track joint replacement units.

Advanced Technical Data Study

DTIC Science & Technology

1975-01-29

will shut down automatically when condenser high pressure causes Pressure Limit Control high pressure switch to release. Press START switch (3...power cable (1) from facility pow- er. Troubleshoot cooling unit, for HI-LOW pressure switch repeated cutout. Refer to AGE ECU Cooling Unit...acti- vate when loss of air flow oc- curred, the pressure switch (3) failed to open circuit. Adjust or replace pressure switch . Refer to

Laser Processed Heat Exchangers

NASA Technical Reports Server (NTRS)

Hansen, Scott

2017-01-01

The Laser Processed Heat Exchanger project will investigate the use of laser processed surfaces to reduce mass and volume in liquid/liquid heat exchangers as well as the replacement of the harmful and problematic coatings of the Condensing Heat Exchangers (CHX). For this project, two scale unit test articles will be designed, manufactured, and tested. These two units are a high efficiency liquid/liquid HX and a high reliability CHX.

USSR Report, Energy, No. 154.

DTIC Science & Technology

1983-07-21

mooring facilities and tank farms in the vicinity of Shevchenko. Neftyanyye Kamni: "Replacing Steam," by Yu. Arutyunov, Chief, Capital Construc...foremen, mechanics and signal men came into the cabin of the unit head. The last preparations for the trip were underway. Captain Petr Alekseyev...platforms, will be supplemented by another mobile unit of the semisubmersible type. It is now being built at the ship- yards of the Astrakhan

A Comparative Analysis of Unit Cohesion in Vietnam

DTIC Science & Technology

2014-06-13

the political process, and result in a communist government; this became known as the Domino Theory . The United States replaced the French and...a theory of linkage; leveraging the political ties of Communist countries, namely the USSR and China, to influence North Vietnam, and deterrence; a...and Henderson provide some of the more popular theories about cohesion. Winkler points out that the relationship between stability, cohesion and

McREL Leadership Responsibilities through the Lens of Data: The Critical Nine

ERIC Educational Resources Information Center

James-Ward, Cheryl; Abuyen, Joy

2015-01-01

At the onset of the 21st century, the United States ushered in a new era of school accountability and reform with the No Child Left Behind Act [NCLB] (United States Department of Education, 2010). Until and unless it is repealed or replaced, this law continues in effect today, with many states now applying to renew their NCLB waivers (Klein,…

Aircrew Sizing Survey 2011

DTIC Science & Technology

2014-10-01

Resource JSF Joint Strike Fighter JPATS Joint Primary Aircraft Training System USMC United States Marine Corps USAF United States Air Force LIST...Surface Anthropometry Resource (CAESAR) was developed for the Joint Strike Fighter (JSF) program. The ACSS was intended to replace the JSF-CAESAR...an aircrew sample was made in 2003 by Hudson et al. They extracted a subset, named JSF CAESAR (Joint Strike Fighter), from the Civilian American and

25 CFR 141.3 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... cost to the owner of replacing an item with one having the same quality and usefulness. (l) Reservation... association or credit union operating under the laws of the United States or the laws of New Mexico, Arizona...

25 CFR 141.3 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-04-01

... cost to the owner of replacing an item with one having the same quality and usefulness. (l) Reservation... association or credit union operating under the laws of the United States or the laws of New Mexico, Arizona...

"Mitochondrial Replacement" Technologies and Human Germline Nuclear Modification.

PubMed

Lane, Alyssa; Nisker, Jeff

2016-08-01

In 2015 the United Kingdom became the first jurisdiction to approve "mitochondrial replacement techniques" (MRT), thereby dropping prohibitions against creating human embryos with a permanently altered genetic make-up for purposes of reproduction. MRT is a misnomer because in fact it is the nucleus of the oocyte of the woman who wants a genetically related child that is transferred to the enucleated oocyte of a woman paid to undergo IVF to provide the oocyte. MRT thus constitutes nuclear transfer, which is prohibited by criminal sanctions under sections of laws on reproductive cloning in Canada, the United States, Australia, and European countries that regulate assisted reproduction. By adopting policies permitting the use of MRT, the United Kingdom has become the first jurisdiction to counteract an international consensus prohibiting germline modification. Analyses of the legal, ethical, and societal implications of MRT in assisted human reproduction are essential. Copyright © 2016 The Society of Obstetricians and Gynaecologists of Canada/La Société des obstétriciens et gynécologues du Canada. Published by Elsevier Inc. All rights reserved.

Unique method of tooth replacement in durophagous placodont marine reptiles, with new data on the dentition of Chinese taxa

PubMed Central

Neenan, James M; Li, Chun; Rieppel, Olivier; Bernardini, Federico; Tuniz, Claudio; Muscio, Giuseppe; Scheyer, Torsten M

2014-01-01

The placodonts of the Triassic period (˜252–201 mya) represent one of the earliest and most extreme specialisations to a durophagous diet of any known reptile group. Exceptionally enlarged crushing tooth plates on the maxilla, dentary and palatine cooperated to form functional crushing areas in the buccal cavity. However, the extreme size of these teeth, combined with the unusual way they occluded, constrained how replacement occurred. Using an extensive micro-computed tomographic dataset of 11 specimens that span all geographic regions and placodont morphotypes, tooth replacement patterns were investigated. In addition, the previously undescribed dental morphologies and formulae of Chinese taxa are described for the first time and incorporated into the analysis. Placodonts have a unique tooth replacement pattern and results follow a phylogenetic trend. The plesiomorphic Placodus species show many replacement teeth at various stages of growth, with little or no discernible pattern. On the other hand, the more derived cyamodontoids tend to have fewer replacement teeth growing at any one time, replacing teeth unilaterally and/or in functional units, thus maintaining at least one functional crushing area at all times. The highly derived placochelyids have fewer teeth and, as a result, only have one or two replacement teeth in the upper jaw. This supports previous suggestions that these taxa had an alternative diet to other placodonts. Importantly, all specimens show at least one replacement tooth growing at the most posterior palatine tooth plates, indicating increased wear at this point and thus the most efficient functional crushing area. PMID:24517163

Optimizing the Navy’s Investment in Space Professionals

DTIC Science & Technology

2011-09-01

UFO Ultra High Frequency Follow-On UHF Ultra High Frequency URL Unrestricted Line USA United States Army USAF United States Air Force USCYBERCOM...LEASAT), and eight UHF Follow-On ( UFO ) satellites all flying in geostationary orbit (GEO). NAVSOC is the principle Navy command that operates, manages...and maintains the DoD’s narrowband UHF capability from five different ground stations. The replacement satellite for the aging UFO system is the

75 FR 55317 - Central Vermont Public Service Corporation; Notice of Application for Amendment of License and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-10

... approval to replace the existing Unit 1 turbine, with a hydraulic capacity of 162 cfs and a nameplate capacity of 1,100 kW, with a new turbine unit having a hydraulic capacity of 177 cfs and a nameplate... 1,900 kW to 2,251 kW, and increase total project hydraulic capacity from 254 cfs to 269 cfs. l. A...

Space Sustainment: A New Approach for America in Space

DTIC Science & Technology

2014-12-01

Power Journal | 118 SCHRIEVER ESSAY WINNER SECOND PLACE United States to break from its laissez - faire traditions and replace them with an ideology of... leadership in space in the future. As the historical evidence suggests, if the United States decides not to promote transparency in space, other nations... leadership , and improves our own SSA through knowledge of other owner/operator satellite positional data.26 Similarly, Deputy Assistant Secretary of Defense

The silver lining of disposable sporicidal privacy curtains in an intensive care unit.

PubMed

Kotsanas, Despina; Wijesooriya, W R P L I; Sloane, Tracy; Stuart, Rhonda L; Gillespie, Elizabeth E

2014-04-01

The environment is a well-known source of health care-acquired infection. Because of the known risk of contamination, patient privacy curtains require frequent changes to decrease the risk of spread from patients to curtain and visa versa. Fourteen disposable sporicidal privacy curtains were tested from December 2012 to June 2013 while hanging in a busy intensive care unit. Significant bacterial pathogens were identified and total bacteria enumerated as colony-forming units. Antimicrobial activity of curtain swatches was also tested against a range of bacteria in the laboratory. Measurements were recorded as zone of inhibition and contact inhibition. A cost analysis to replace standard curtains with disposable sporicidal curtains was also undertaken. Cultures grew low numbers of skin and environmental microorganisms with no methicillin-resistant Staphylococcus aureus, carbapenem-resistant Enterobacteriaceae, or Clostridium difficile detected. Vancomycin-resistant enterococci were recovered in very low numbers from 2 curtains where vancomycin-resistant enterococci-infected patients had been located. Privacy curtains demonstrated antimicrobial activity against C difficile and 13 additional bacterial pathogens. We conclude that disposable sporicidal privacy curtains are cost-effective and best replaced at 6 months in a high-risk area such as an intensive care unit. Copyright © 2014 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.

Soft tissue balancing in total shoulder replacement.

PubMed

Mueller, Maike; Hoy, Gregory

2014-03-01

Total shoulder arthroplasty is now capable of recreating near anatomic reproduction of native bony shoulder anatomy, but the function and longevity of anatomic shoulder replacement is dependent on a competent soft tissue envelope and adequate motoring of all musculo-tendinous units about the shoulder. Balancing the soft tissues requires understanding of the anatomy and pathology, as well as technical skills. The advent of reverse shoulder biomechanics has brought with it special requirements of understanding of the soft tissue elements still left in the shoulder despite major rotator cuff deficiency.

KSC-08pd2361

NASA Image and Video Library

2008-08-08

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, the Fine Guidance Sensor Scientific Instrument Protective Enclosure, or FSIPE, cover has been installed on the Orbital Replacement Unit Carrier, or ORUC. The ORUC is one of three carriers that are being prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the fifth and final Hubble servicing mission, STS-125. Launch is targeted for Oct. 8. PHoto credit: NASA/Jack Pfaller

KSC-08pd2358

NASA Image and Video Library

2008-08-08

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, workers help guide the Fine Guidance Sensor Scientific Instrument Protective Enclosure, or FSIPE, cover alongside the Orbital Replacement Unit Carrier, or ORUC, for installation. The ORUC is one of three carriers that are being prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the fifth and final Hubble servicing mission, STS-125. Launch is targeted for Oct. 8. PHoto credit: NASA/Jack Pfaller

KSC-08pd2357

NASA Image and Video Library

2008-08-08

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, an overhead crane lowers the Fine Guidance Sensor Scientific Instrument Protective Enclosure, or FSIPE, cover alongside the Orbital Replacement Unit Carrier, or ORUC, for installation. The ORUC is one of three carriers that are being prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the fifth and final Hubble servicing mission, STS-125. Launch is targeted for Oct. 8. PHoto credit: NASA/Jack Pfaller

KSC-08pd2359

NASA Image and Video Library

2008-08-08

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, workers help maneuver the Fine Guidance Sensor Scientific Instrument Protective Enclosure, or FSIPE, cover alongside the Orbital Replacement Unit Carrier, or ORUC, for installation. The ORUC is one of three carriers that are being prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the fifth and final Hubble servicing mission, STS-125. Launch is targeted for Oct. 8. PHoto credit: NASA/Jack Pfaller

KSC-08pd2354

NASA Image and Video Library

2008-08-08

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, the Fine Guidance Sensor Scientific Instrument Protective Enclosure, or FSIPE, cover awaits a move to be installed on the Orbital Replacement Unit Carrier, or ORUC. The ORUC is one of three carriers that are being prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the fifth and final Hubble servicing mission, STS-125. Launch is targeted for Oct. 8. PHoto credit: NASA/Jack Pfaller

KSC-08pd2360

NASA Image and Video Library

2008-08-08

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, workers help maneuver the Fine Guidance Sensor Scientific Instrument Protective Enclosure, or FSIPE, cover into place on the Orbital Replacement Unit Carrier, or ORUC, for installation. The ORUC is one of three carriers that are being prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the fifth and final Hubble servicing mission, STS-125. Launch is targeted for Oct. 8. PHoto credit: NASA/Jack Pfaller

Valeri Tokarev and Julie Payette replace battery chargers in the FGB/Zarya module

NASA Image and Video Library

2017-04-20

S96-E-5086 (31 May 1999) --- Astronaut Julie Payette and cosmonaut Valery I. Tokarev, mission specialists, are in the process of replacing all 18 of the battery charge/discharge units that support Zarya's six nickel-cadmium batteries. Known by the Russian acronym, "MIRTs," the batteries are thought to have been responsible for voltage problems first detected in January of this year, as Zarya, docked to Unity, orbited Earth. The photo was taken with an electronic still camera (ESC) at 03:15:38 GMT, May 31, 1999.

76 FR 62092 - Filing Procedures

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-06

... INTERNATIONAL TRADE COMMISSION Filing Procedures AGENCY: International Trade Commission. ACTION: Notice of issuance of Handbook on Filing Procedures. SUMMARY: The United States International Trade Commission (``Commission'') is issuing a Handbook on Filing Procedures to replace its Handbook on Electronic...

iss034e033850

NASA Image and Video Library

2013-01-23

ISS034-E-033850 (23 Jan. 2013) --- Canadian Space Agency astronaut Chris Hadfield, Expedition 34 flight engineer, continues work to remove and replace the Service and Performance Checkout Unit (SPCU) Heat Exchanger inside the Quest airlock of the International Space Station.

Program Predicts Nonlinear Inverter Performance

NASA Technical Reports Server (NTRS)

Al-Ayoubi, R. R.; Oepomo, T. S.

1985-01-01

Program developed for ac power distribution system on Shuttle orbiter predicts total load on inverters and node voltages at each of line replaceable units (LRU's). Mathematical model simulates inverter performance at each change of state in power distribution system.

The Frame Constraint on Experimentally Elicited Speech Errors in Japanese.

PubMed

Saito, Akie; Inoue, Tomoyoshi

2017-06-01

The so-called syllable position effect in speech errors has been interpreted as reflecting constraints posed by the frame structure of a given language, which is separately operating from linguistic content during speech production. The effect refers to the phenomenon that when a speech error occurs, replaced and replacing sounds tend to be in the same position within a syllable or word. Most of the evidence for the effect comes from analyses of naturally occurring speech errors in Indo-European languages, and there are few studies examining the effect in experimentally elicited speech errors and in other languages. This study examined whether experimentally elicited sound errors in Japanese exhibits the syllable position effect. In Japanese, the sub-syllabic unit known as "mora" is considered to be a basic sound unit in production. Results showed that the syllable position effect occurred in mora errors, suggesting that the frame constrains the ordering of sounds during speech production.

Purification, crystallization, preliminary X-ray diffraction and molecular-replacement studies of great cormorant (Phalacrocorax carbo) haemoglobin.

PubMed

Jagadeesan, G; Malathy, P; Gunasekaran, K; Harikrishna Etti, S; Aravindhan, S

2014-11-01

Haemoglobin is the iron-containing oxygen-transport metalloprotein that is present in the red blood cells of all vertebrates. In recent decades, there has been substantial interest in attempting to understand the structural basis and functional diversity of avian haemoglobins. Towards this end, purification, crystallization, preliminary X-ray diffraction and molecular-replacement studies have been carried out on cormorant (Phalacrocorax carbo) haemoglobin. Crystals were grown by the hanging-drop vapour-diffusion method using PEG 3350, NaCl and glycerol as precipitants. The crystals belonged to the trigonal system P3₁21, with unit-cell parameters a=b=55.64, c=153.38 Å, β=120.00°; a complete data set was collected to a resolution of 3.5 Å. Matthews coefficient analysis indicated that the crystals contained a half-tetramer in the asymmetric unit.

Crystallization and preliminary X-ray analysis of Leishmania major glyoxalase I

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ariza, Antonio; Vickers, Tim J.; Greig, Neil

2005-08-01

The detoxification enzyme glyoxalase I from L. major has been crystallized. Preliminary molecular-replacement calculations indicate the presence of three glyoxalase I dimers in the asymmetric unit. Glyoxalase I (GLO1) is a putative drug target for trypanosomatids, which are pathogenic protozoa that include the causative agents of leishmaniasis. Significant sequence and functional differences between Leishmania major and human GLO1 suggest that it may make a suitable template for rational inhibitor design. L. major GLO1 was crystallized in two forms: the first is extremely disordered and does not diffract, while the second, an orthorhombic form, produces diffraction to 2.0 Å. Molecular-replacement calculationsmore » indicate that there are three GLO1 dimers in the asymmetric unit, which take up a helical arrangement with their molecular dyads arranged approximately perpendicular to the c axis. Further analysis of these data are under way.« less

Simulation of a Flywheel Electrical System for Aerospace Applications

NASA Technical Reports Server (NTRS)

Truong, Long V.; Wolff, Frederick J.; Dravid, Narayan V.

2000-01-01

A Flywheel Energy Storage Demonstration Project was initiated at the NASA Glenn Research Center as a possible replacement for the battery energy storage system on the International Space Station (ISS). While the hardware fabrication work was being performed at a university and contractor's facility, the related simulation activity was begun at Glenn. At the top level, Glenn researchers simulated the operation of the ISS primary electrical system (as described in another paper) with the Flywheel Energy Storage Unit (FESU) replacing one Battery Charge and Discharge Unit (BCDU). The FESU consists of a Permanent Magnet Synchronous Motor/Generator (PMSM), which is connected to the flywheel; the power electronics that connects the PMSM to the ISS direct-current bus; and the associated controller. The PMSM model is still under development, but this paper describes the rest of the FESU model-the simulation of the converter and the associated control system that regulates energy transfer to and from the flywheel.

Vertical nuclear proliferation.

PubMed

Sidel, Victor W

2007-01-01

All the nuclear-weapon states are working to develop new nuclear-weapon systems and upgrade their existing ones. Although the US Congress has recently blocked further development of small nuclear weapons and earth-penetrating nuclear weapons, the United States is planning a range of new warheads under the Reliable Replacement Warhead programme, and renewing its nuclear weapons infrastructure. The United Kingdom is spending 1 billion pounds sterling on updating the Atomic Weapons Establishment at Aldermaston, and about 20 billion pounds sterling on replacing its Vanguard submarines and maintaining its Trident warhead stockpile. The US has withdrawn from the Anti-Ballistic Missile Treaty and plans to install missile defence systems in Poland and the Czech Republic; Russia threatens to upgrade its nuclear countermeasures. The nuclear-weapon states should comply with their obligations under Article VI of the Non-Proliferation Treaty, as summarised in the 13-point plan agreed at the 2000 NPT Review Conference, and they should negotiate a Nuclear Weapons Convention.

Wrist Camera Orientation for Effective Telerobotic Orbital Replaceable Unit (ORU) Changeout

NASA Technical Reports Server (NTRS)

Jones, Sharon Monica; Aldridge, Hal A.; Vazquez, Sixto L.

1997-01-01

The Hydraulic Manipulator Testbed (HMTB) is the kinematic replica of the Flight Telerobotic Servicer (FTS). One use of the HMTB is to evaluate advanced control techniques for accomplishing robotic maintenance tasks on board the Space Station. Most maintenance tasks involve the direct manipulation of the robot by a human operator when high-quality visual feedback is important for precise control. An experiment was conducted in the Systems Integration Branch at the Langley Research Center to compare several configurations of the manipulator wrist camera for providing visual feedback during an Orbital Replaceable Unit changeout task. Several variables were considered such as wrist camera angle, camera focal length, target location, lighting. Each study participant performed the maintenance task by using eight combinations of the variables based on a Latin square design. The results of this experiment and conclusions based on data collected are presented.

STS-84 oxygen generator for Mir on display at SPACEHAB

NASA Technical Reports Server (NTRS)

1997-01-01

An oxygen generator destined to replace a malfunctioning unit on the Russian Mir Space Station is the object of much curiosity during preflight preparations in the SPACEHAB Payload Processing Facility. A SPACEHAB Double Module on the Space Shuttle Atlantis will carry the oxygen generator to Mir during STS-84, the sixth Shuttle-Mir docking. The nearly 300-pound generator, manufactured by RSC Energia in Russia, will replace one of two Mir units that have been malfunctioning recently. The generator functions by electrolysis, which separates water into its oxygen and hydrogen components. The hydrogen is vented and the oxygen is used for breathing by the Mir crew. The generator is 4.2 feet in length and 1.4 feet in diameter. STS-84, which is planned to include a Mir crew exchange of astronaut C. Michael Foale for Jerry M. Linenger, is targeted for a May 15 liftoff.

Options Studied for Managing Space Station Solar Array Electrical Hazards for Sequential Shunt Unit Replacement

NASA Technical Reports Server (NTRS)

Delleur, Ann M.; Kerslake, Thomas W.; Levy, Robert K.

2004-01-01

The U.S. solar array strings on the International Space Station are connected to a sequential shunt unit (SSU). The job of the SSU is to shunt, or short, the excess current from the solar array, such that just enough current is provided downstream to maintain the 160-V bus voltage while meeting the power load demand and recharging the batteries. Should an SSU fail on-orbit, it would be removed and replaced with the on-orbit spare during an astronaut space walk or extravehicular activity (EVA) (see the photograph). However, removing an SSU during an orbit Sun period with input solar array power connectors fully energized could result in substantial hardware damage and/or safety risk to the EVA astronaut. The open-circuit voltage of cold solar-array strings can exceed 320 V, and warm solar-array strings could feed a short circuit with a total current level exceeding 240 A.

Tooth replacement and putative odontogenic stem cell niches in pharyngeal dentition of medaka (Oryzias latipes).

PubMed

Abduweli, Dawud; Baba, Otto; Tabata, Makoto J; Higuchi, Kazunori; Mitani, Hiroshi; Takano, Yoshiro

2014-04-01

The small-sized teleost fish medaka, Oryzias latipes, has as many as 1000 pharyngeal teeth undergoing continuous replacement. In this study, we sought to identify the tooth-forming units and determine its replacement cycles, and further localize odontogenic stem cell niches in the pharyngeal dentition of medaka to gain insights into the mechanisms whereby continuous tooth replacement is maintained. Three-dimensional reconstruction of pharyngeal epithelium and sequential fluorochrome labeling of pharyngeal bones and teeth indicated that the individual functional teeth and their successional teeth were organized in families, each comprising up to five generations of teeth and successional tooth germs, and that the replacement cycle of functional teeth was approximately 4 weeks. BrdU label/chase experiments confirmed the existence of clusters of label-retaining epithelial cells at the posterior end of each tooth family where the expression of pluripotency marker Sox2 was confirmed by in situ hybridization. Label-retaining cells were also identified in the mesoderm immediately adjacent to the posterior end of each tooth family. These data suggest the importance of existence of slow-cycling dental epithelial cells and Sox2 expressions at the posterior end of each tooth family to maintain continuous tooth formation and replacement in the pharyngeal dentition of medaka.

Trade study comparing specimen chamber servicing methods for the Space Station Centrifuge Facility

NASA Technical Reports Server (NTRS)

Calvisi, Michael L.; Sun, Sidney C.

1991-01-01

The Specimen Chamber Service Unit, a component of the Space Station Centrifuge Facility, must provide a clean enclosure on a continuing basis for the facility's plant, rodent and primate specimens. The specimen chambers can become soiled and can require periodic servicing to maintain a clean environment for the specimens. Two methods of servicing the specimen chambers are discussed: washing the chambers with an on-board washer, or disposing of the soiled chambers and replacing them with clean ones. Many of these issues are addressed by developing several servicing options, using either cleaning or replacement as the method of providing clean specimen chambers, and then evaluating each option according to a set of established quantitative and qualitative criteria. Disposing and replacing the Specimen Chambers is preferable to washing them.

A replacement LH2 recirculation line before installation in Discovery

NASA Technical Reports Server (NTRS)

1999-01-01

Gary Hamilton (left) and James Stickley, both with United Space Alliance, check out a spare four-inch diameter LH2 recirculation line that will be used to replace a damaged LH2 line in the orbiter Discovery. The line recirculates hydrogen from the Shuttle main engines back to the external tank during prelaunch engine conditioning. Workers noted a dent in the line during routine aft compartment inspections Tuesday, Dec. 7. The dent measures 12 inches long and about =-inch deep. Managers expect the replacement work to take about 3 days, followed by system retests and final aft compartment close-outs. Preliminary assessments reflect a launch date of Space Shuttle Discovery on mission STS-103 no earlier than Dec. 16. STS-103 is the third servicing mission for the Hubble Space Telescope.

A replacement LH2 recirculation line before installation in Discovery

NASA Technical Reports Server (NTRS)

1999-01-01

James Stickley (left) and Derry Dilby (right), who are with United Space Alliance, check over a spare four-inch diameter LH2 recirculation line that will be used to replace a damaged LH2 line in the orbiter Discovery. The line recirculates hydrogen from the Shuttle main engines back to the external tank during prelaunch engine conditioning. Workers noted a dent in the line during routine aft compartment inspections Tuesday, Dec. 7. The dent measures 12 inches long and about =-inch deep. Managers expect the replacement work to take about 3 days, followed by system retests and final aft compartment close-outs. Preliminary assessments reflect a launch date of Space Shuttle Discovery on mission STS-103 no earlier than Dec. 16. STS-103 is the third servicing mission for the Hubble Space Telescope.

ISS Expedition 53 U.S. Spacewalk 46

NASA Image and Video Library

2017-10-20

Outside the International Space Station, Expedition 53 Commander Randy Bresnik and Flight Engineer Joe Acaba of NASA conducted a spacewalk Oct. 20 to continue upgrades to and maintenance of station hardware. It was the third spacewalk in two weeks for Expedition 53 crewmembers outside the Quest airlock. During the excursion, Bresnik and Acaba replaced a failed camera light on the new Latching End Effector “hand” on the Canadarm2 robotic arm, installed a new high definition camera on the starboard truss of the complex, replaced a fuse on the Dextre Special Dexterous Manipulator attachment for the arm and removed thermal blankets from two spare electrical routing units for future robotic replacement work, if required. It was the fifth spacewalk in Bresnik’s career and the third for Acaba.

MOOSE: Manned On-Orbit Servicing Equipment

NASA Technical Reports Server (NTRS)

Budinoff, J. (Editor); Leontsinis, N. (Editor); Lane, J. (Editor); Singh, R. (Editor); Angelone, K.; Boswell, C.; Chamberlain, I.; Concha, M.; Corrodo, M.; Custodio, O.

1993-01-01

The ability to service satellites has thus far been limited to low earth orbit platforms within reach of the Space Shuttle. Other orbits, such as geosynchronous orbits containing high-value spacecraft have not been attainable by a servicing vehicle. The useful life of a satellite can be extended by replacing spent propellant and damaged orbital replacement units, forestalling the need for eventual replacement. This growing need for satellite on-orbits servicing can be met by the Manned On-Orbit Servicing Equipment (MOOSE). Missions requiring orbit transfer capability, precision manipulation and maneuvering, and man-in-the-loop control can be accomplished using MOOSE. MOOSE is a flexible, reusable, single operator, aerobraking spacecraft designed to refuel, repair, and service orbiting spacecraft. MOOSE will be deployed from Space Station Freedom, (SSF), where it will be stored, resupplied, and refurbished.

KSC-06pd0022

NASA Image and Video Library

2006-01-11

KENNEDY SPACE CENTER, FLA. - In the Thermal Protection System Facility, Tim Wright, engineering manager with United Space Alliance, tests a new tile, called "Boeing replacement insulation" or "BRI-18." The new tiles will gradually replace older tiles around main landing gear doors, external tank doors and nose landing gear doors. Currently, 10 tiles have been processed inside the facility. Discovery will receive the first BRI-18 tiles. Technicians inside the Orbiter Processing Facility are performing fit checks and will begin bonding the tiles to the vehicle this month. The raw material is manufactured by The Boeing Company in Huntington Beach, Calif. Replacing older tile with the BRI-18 tile in strategic areas is one of the Columbia Accident Investigation Board's recommendations to strengthen the orbiters. The tiles are more impact resistant than previous designs, enhancing the crew’s safety.

KSC-06pd0021

NASA Image and Video Library

2006-01-11

KENNEDY SPACE CENTER, FLA. - In the Thermal Protection System Facility, Tim Wright, engineering manager with United Space Alliance, tests a new tile, called "Boeing replacement insulation" or "BRI-18." The new tiles will gradually replace older tiles around main landing gear doors, external tank doors and nose landing gear doors. Currently, 10 tiles have been processed inside the facility. Discovery will receive the first BRI-18 tiles. Technicians inside the Orbiter Processing Facility are performing fit checks and will begin bonding the tiles to the vehicle this month. The raw material is manufactured by The Boeing Company in Huntington Beach, Calif. Replacing older tile with the BRI-18 tile in strategic areas is one of the Columbia Accident Investigation Board's recommendations to strengthen the orbiters. The tiles are more impact resistant than previous designs, enhancing the crew’s safety.

Language Profile in Congenital Hypothyroid Children Receiving Replacement Therapy.

PubMed

Soliman, Hend; Abdel Hady, Aisha Fawzy; Abdel Hamid, Asmaa; Mahmoud, Heba

2016-01-01

The aim of this work was to evaluate receptive and expressive language skills in children with congenital hypothyroidism receiving early hormonal replacement treatment before the age of 3 months and to identify any subtle areas of weaknesses in their language development to check the necessity for future language intervention. The study was conducted on 30 hypothyroid children receiving hormonal replacement. They were subdivided into group I (5-8 years 11 months; 12 cases) and group II (9-12 years 11 months; 18 cases). All patients were subjected to a protocol of assessment applied in the Diabetes, Endocrine and Metabolism Pediatric Unit (DEMPU) and evaluation of language skills by the REAL scale. The younger group reached average Arabic language scores, while the older group showed moderate language delay. Early replacement therapy supports language development in young children. However, longitudinal and follow-up studies are required to identify difficulties presenting at older ages that may affect children in the academic settings. © 2016 S. Karger AG, Basel.

Evaluation of plant biomass resources available for replacement of fossil oil

PubMed Central

Henry, Robert J

2010-01-01

The potential of plants to replace fossil oil was evaluated by considering the scale of production required, the area of land needed and the types of plants available. High yielding crops (50 tonnes/ha) that have a high conversion efficiency (75%) would require a global land footprint of around 100 million ha to replace current (2008) oil consumption. Lower yielding or less convertible plants would require a larger land footprint. Domestication of new species as dedicated energy crops may be necessary. A systematic analysis of higher plants and their current and potential uses is presented. Plant biotechnology provides tools to improve the prospects of replacing oil with plant-derived biomass by increasing the amount of biomass produced per unit area of land and improving the composition of the biomass to increase the efficiency of conversion to biofuel and biomaterials. Options for the production of high value coproducts and the expression of processing aids such as enzymes in the plant may add further value to plants as bioenergy resources. PMID:20070873

Mass and Reliability System (MaRS)

NASA Technical Reports Server (NTRS)

Barnes, Sarah

2016-01-01

The Safety and Mission Assurance (S&MA) Directorate is responsible for mitigating risk, providing system safety, and lowering risk for space programs from ground to space. The S&MA is divided into 4 divisions: The Space Exploration Division (NC), the International Space Station Division (NE), the Safety & Test Operations Division (NS), and the Quality and Flight Equipment Division (NT). The interns, myself and Arun Aruljothi, will be working with the Risk & Reliability Analysis Branch under the NC Division's. The mission of this division is to identify, characterize, diminish, and communicate risk by implementing an efficient and effective assurance model. The team utilizes Reliability and Maintainability (R&M) and Probabilistic Risk Assessment (PRA) to ensure decisions concerning risks are informed, vehicles are safe and reliable, and program/project requirements are realistic and realized. This project pertains to the Orion mission, so it is geared toward a long duration Human Space Flight Program(s). For space missions, payload is a critical concept; balancing what hardware can be replaced by components verse by Orbital Replacement Units (ORU) or subassemblies is key. For this effort a database was created that combines mass and reliability data, called Mass and Reliability System or MaRS. The U.S. International Space Station (ISS) components are used as reference parts in the MaRS database. Using ISS components as a platform is beneficial because of the historical context and the environment similarities to a space flight mission. MaRS uses a combination of systems: International Space Station PART for failure data, Vehicle Master Database (VMDB) for ORU & components, Maintenance & Analysis Data Set (MADS) for operation hours and other pertinent data, & Hardware History Retrieval System (HHRS) for unit weights. MaRS is populated using a Visual Basic Application. Once populated, the excel spreadsheet is comprised of information on ISS components including: operation hours, random/nonrandom failures, software/hardware failures, quantity, orbital replaceable units (ORU), date of placement, unit weight, frequency of part, etc. The motivation for creating such a database will be the development of a mass/reliability parametric model to estimate mass required for replacement parts. Once complete, engineers working on future space flight missions will have access a mean time to failures and on parts along with their mass, this will be used to make proper decisions for long duration space flight missions

Developing Ultra Reliable Life Support for the Moon and Mars

NASA Technical Reports Server (NTRS)

Jones, Harry W.

2009-01-01

Recycling life support systems can achieve ultra reliability by using spares to replace failed components. The added mass for spares is approximately equal to the original system mass, provided the original system reliability is not very low. Acceptable reliability can be achieved for the space shuttle and space station by preventive maintenance and by replacing failed units, However, this maintenance and repair depends on a logistics supply chain that provides the needed spares. The Mars mission must take all the needed spares at launch. The Mars mission also must achieve ultra reliability, a very low failure rate per hour, since it requires years rather than weeks and cannot be cut short if a failure occurs. Also, the Mars mission has a much higher mass launch cost per kilogram than shuttle or station. Achieving ultra reliable space life support with acceptable mass will require a well-planned and extensive development effort. Analysis must define the reliability requirement and allocate it to subsystems and components. Technologies, components, and materials must be designed and selected for high reliability. Extensive testing is needed to ascertain very low failure rates. Systems design should segregate the failure causes in the smallest, most easily replaceable parts. The systems must be designed, produced, integrated, and tested without impairing system reliability. Maintenance and failed unit replacement should not introduce any additional probability of failure. The overall system must be tested sufficiently to identify any design errors. A program to develop ultra reliable space life support systems with acceptable mass must start soon if it is to produce timely results for the moon and Mars.

Control of ammonia and urea emissions from urea manufacturing facilities of Petrochemical Industries Company (PIC), Kuwait.

PubMed

Khan, A R; Al-Awadi, L; Al-Rashidi, M S

2016-06-01

Petrochemical Industries Company (PIC) in Kuwait has mitigated the pollution problem of ammonia and urea dust by replacing the melting and prilling units of finished-product urea prills with an environmentally friendly granulation process. PIC has financed a research project conducted by the Coastal and Air Pollution Program's research staff at the Kuwait Institute for Scientific Research to assess the impact of pollution control strategies implemented to maintain a healthy productive environment in and around the manufacturing premises. The project was completed in three phases: the first phase included the pollution monitoring of the melting and prilling units in full operation, the second phase covered the complete shutdown period where production was halted completely and granulation units were installed, and the last phase encompassed the current modified status with granulation units in full operation. There was substantial decrease in ammonia emissions, about 72%, and a 52.7% decrease in urea emissions with the present upgrading of old melting and prilling units to a state-of-the-art technology "granulation process" for a final finished product. The other pollutants, sulfur dioxide (SO2), nitrogen oxides (NOx), and volatile organic compounds (VOCs), have not shown any significant change, as the present modification has not affected the sources of these pollutants. Petrochemical Industries Company (PIC) in Kuwait has ammonia urea industries, and there were complaints about ammonia and urea dust pollution. PIC has resolved this problem by replacing "melting and prilling unit" of final product urea prills by more environmentally friendly "granulation unit." Environmental Pollution and Climate Program has been assigned the duty of assessing the outcome of this change and how that influenced ammonia and urea dust emissions from the urea manufacturing plant.

The impact of changing nicotine replacement therapy licensing laws in the United Kingdom: findings from the International Tobacco Control Four Country Survey.

PubMed

Shahab, Lion; Cummings, K Michael; Hammond, David; Borland, Ron; West, Robert; McNeill, Ann

2009-08-01

To evaluate the impact of a new licence for some nicotine replacement therapy products (NRT) for cutting down to stop (CDTS) on changes in the pattern of NRT use. Quasi-experimental design comparing changes in NRT use across two waves of a population-based, replenished-panel, telephone survey conducted before and after the introduction of new licensing laws in the United Kingdom with changes in NRT use in three comparison countries (Australia, Canada and United States) without a licensing change. A total of 7386 and 7013 smokers and recent ex-smokers participating in the 2004 and/or 2006/7 survey. Data were collected on demographic and smoking characteristics as well as NRT use and access. In order to account for interdependence resulting from some participants being present in both waves, generalized estimation equations with an exchangeable correlation matrix were used to assess within-country changes and linear and logistic regressions to assess between-country differences in adjusted analyses. NRT use was more prevalent in the United Kingdom and increased across waves in all countries but no wave x country interaction was observed. There was no evidence that the licensing change increased the prevalence of CDTS or the use of NRT (irrespective of how it was accessed) for CDTS in the United Kingdom relative to comparison countries. There was also no evidence for a change in concurrent smoking and NRT use among smokers not attempting to stop in the United Kingdom relative to comparison countries. The addition of the CDTS licence for some NRT products in the United Kingdom appears to have had very limited, if any, impact on NRT use in the first year after the licence change.

AUTOMOTIVE DIESEL MAINTENANCE 1. UNIT XI, PART I--MAINTAINING THE FUEL SYSTEM (PART I), CUMMINS DIESEL ENGINES, PART II--UNIT REPLACEMENT (ENGINE).

ERIC Educational Resources Information Center

Human Engineering Inst., Cleveland, OH.

THIS MODULE OF A 30-MODULE COURSE IS DESIGNED TO DEVELOP AN UNDERSTANDING OF DIFFERENCES BETWEEN TWO AND FOUR CYCLE ENGINES, THE OPERATION AND MAINTENANCE OF THE DIESEL ENGINE FUEL SYSTEM, AND THE PROCEDURES FOR DIESEL ENGINE REMOVAL. TOPICS ARE (1) REVIEW OF TWO CYCLE AND FOUR CYCLE CONCEPT, (2) SOME BASIC CHARACTERISTICS OF FOUR CYCLE ENGINES,…

Army Medical Department Officers in Division Assignments: Prepared to Succeed, or Doomed to Fail?

DTIC Science & Technology

1992-04-15

officers for tactical unit asgnments. IL.BACKGROUND In the late 1970s, the concept of multi-functional. forward support battalions (FSB) i divisions...functions. Headquarters made up of officers who were each experienced in a single discipline replaced these centers of expertise. The concept assumed that...the evacuation of casualties and movement of the medical unit. Although many of these capabilities exists in the FSB concept , flexibility and

United States Air Force Security Forces in an Era of Terrorist Threats

DTIC Science & Technology

1999-06-01

their primary duties. The third alternative is to eliminate the Palace Tenure deployments of security personnel and replace them with dedicated units...The Phoenix Raven program, the 820th Security Forces Group, and Palace Tenure commitments. The specified mission varies by organization, but the...820th Security Forces Group. January 1999, slide 4. 166 Statement of LT. Col. Larry A. Buckingham , 820th Security Forces Group Commander, “820th Security

Solid-State Thyratron Replacement. Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roth, Ian

2017-12-12

Under this SBIR, DTI developed a solid-state switch as an alternative to legacy thyratron equipment. Our Phase II objective was to make a solid-state thyratron replacement that would provide equivalent or better performance, much higher reliability (at least a 20 year lifetime, compared to a thyratron’s two-year lifetime) and would sell for ~3x the cost of a thyratron, or less than $40k. We were successful in building a solid-state switch which could reliably function as a thyratron replacement. The unit was designed to directly replace the thyratrons currently being used at SLAC’s Linac Coherent Light Source (LCLS), and was builtmore » in a tank that was small enough to fit into the existing thyratron cabinet, providing a true form-fit-function replacement path. We tested the switch at the full operating specifications: 48 kV, 6.3 kA, and 1 µs risetime. We also demonstrated a peak-to-peak pulse jitter of 1.5 ns, which is five times shorter than is typical for thyratrons. This lower jitter would improve the performance of the LCLS beam. The predicted reliability is more than 80 years, which is 40 times greater than a thyratron.« less

Cell biology of sarcomeric protein engineering: disease modeling and therapeutic potential.

PubMed

Thompson, Brian R; Metzger, Joseph M

2014-09-01

The cardiac sarcomere is the functional unit for myocyte contraction. Ordered arrays of sarcomeric proteins, held in stoichiometric balance with each other, respond to calcium to coordinate contraction and relaxation of the heart. Altered sarcomeric structure-function underlies the primary basis of disease in multiple acquired and inherited heart disease states. Hypertrophic and restrictive cardiomyopathies are caused by inherited mutations in sarcomeric genes and result in altered contractility. Ischemia-mediated acidosis directly alters sarcomere function resulting in decreased contractility. In this review, we highlight the use of acute genetic engineering of adult cardiac myocytes through stoichiometric replacement of sarcomeric proteins in these disease states with particular focus on cardiac troponin I. Stoichiometric replacement of disease causing mutations has been instrumental in defining the molecular mechanisms of hypertrophic and restrictive cardiomyopathy in a cellular context. In addition, taking advantage of stoichiometric replacement through gene therapy is discussed, highlighting the ischemia-resistant histidine-button, A164H cTnI. Stoichiometric replacement of sarcomeric proteins offers a potential gene therapy avenue to replace mutant proteins, alter sarcomeric responses to pathophysiologic insults, or neutralize altered sarcomeric function in disease. © 2014 Wiley Periodicals, Inc.

Inventory of methane emissions from U.S. cattle

NASA Astrophysics Data System (ADS)

Westberg, H.; Lamb, B.; Johnson, K. A.; Huyler, M.

2001-01-01

Many countries, including the United States, are in the process of inventorying greenhouse gas emissions as a prerequisite for designing control strategies. We have developed a measurement-based inventory of methane emissions from cattle in the United States. Methane emission factors were established for the major livestock groups using an internal tracer method. The groups studied included cows, replacement heifers, slaughter cattle, calves, and bulls in the beef sector and cows plus replacement heifers in the dairy industry. Since methane emission is dependent on the quality and quantity of feed, diets were chosen that are representative of the feed regimes utilized by producers in the United States. Regional cattle populations, obtained from U.S. Department of Agriculture statistics, were combined with the methane emission factors to yield regional emission estimates. The methane totals from the five regions were then summed to give a U.S. inventory of cattle emissions for 1990, 1992, 1994, 1996, and 1998. Annual releases ranged from 6.50 Tg in 1990 to a high of 6.98 Tg in 1996. On a regional scale the North Central region of the United States had the largest methane emissions from livestock followed by the South Central and the West. The beef cow group released the most methane (˜2.5 Tg yr-1) followed by slaughter cattle (˜1.7 Tg yr-1) and dairy cows at about 1.5 Tg yr-1. Methane released by cattle in the United States contributes about 11% of the global cattle source.

Balanced crystalloids versus saline in the intensive care unit: study protocol for a cluster-randomized, multiple-crossover trial.

PubMed

Semler, Matthew W; Self, Wesley H; Wang, Li; Byrne, Daniel W; Wanderer, Jonathan P; Ehrenfeld, Jesse M; Stollings, Joanna L; Kumar, Avinash B; Hernandez, Antonio; Guillamondegui, Oscar D; May, Addison K; Siew, Edward D; Shaw, Andrew D; Bernard, Gordon R; Rice, Todd W

2017-03-16

Saline, the intravenous fluid most commonly administered to critically ill adults, contains a high chloride content, which may be associated with acute kidney injury and death. Whether using balanced crystalloids rather than saline decreases the risk of acute kidney injury and death among critically ill adults remains unknown. The Isotonic Solutions and Major Adverse Renal Events Trial (SMART) is a pragmatic, cluster-level allocation, cluster-level crossover trial being conducted between 1 June 2015 and 30 April 2017 in five intensive care units at Vanderbilt University Medical Center in Nashville, TN, USA. SMART compares saline (0.9% sodium chloride) with balanced crystalloids (clinician's choice of lactated Ringer's solution or Plasma-Lyte A®). Each intensive care unit is assigned to provide either saline or balanced crystalloids each month, with the assigned crystalloid alternating monthly over the course of the trial. All adults admitted to participating intensive care units during the study period are enrolled and followed until hospital discharge or 30 days after enrollment. The anticipated enrollment is approximately 14,000 patients. The primary outcome is Major Adverse Kidney Events within 30 days-the composite of in-hospital death, receipt of new renal replacement therapy, or persistent renal dysfunction (discharge creatinine ≥200% of baseline creatinine). Secondary clinical outcomes include in-hospital mortality, intensive care unit-free days, ventilator-free days, vasopressor-free days, and renal replacement therapy-free days. Secondary renal outcomes include new renal replacement therapy receipt, persistent renal dysfunction, and incidence of stage 2 or higher acute kidney injury. This ongoing pragmatic trial will provide the largest and most comprehensive comparison to date of clinical outcomes with saline versus balanced crystalloids among critically ill adults. For logistical reasons, SMART was prospectively registered separately for the medical ICU (SMART-MED; ClinicalTrials.gov identifier: NCT02444988 ; registered on 11 May 2015; date of first patient enrollment: 1 June 2015) and the nonmedical ICUs (SMART-SURG; ClinicalTrials.gov identifier: NCT02547779 ; registered on 9 September 2015; date of first patient enrollment: 1 October 2015).

Four-unit fixed dental prostheses replacing the maxillary incisors supported by two narrow-diameter implants - a five-year case series.

PubMed

Moráguez, Osvaldo; Vailati, Francesca; Grütter, Linda; Sailer, Irena; Belser, Urs C

2017-07-01

(1) To determine the survival rate of 10 four-unit fixed dental prostheses (FDPs) replacing the four maxillary incisors, supported by 20 narrow-diameter implants (NDIs), (2) to assess the incidence of mechanical and biological complications, and (3) to evaluate bone level changes longitudinally after final FDP insertion. Ten patients (six women, four men), mean age 49.4 ± 12.6 years, were treated with a four-unit anterior maxillary FDP (six screw-retained; four cemented). Biological parameters, eventual technical complications, radiographic measurements, and study casts were assessed at 1 (baseline), 3, and 5 years after implant placement. A multilevel logistic regression test was performed on clinical parameters and bone level changes (significance level P < 0.05). The 5-year implant and FDP survival rate was 100%. Mean modified plaque index (mPI) values were 0.03 and 0.02 at 3 and 5 years, significantly lower when compared to mPI (0.11 ± 0.31) at 1 year. Mean modified sulcus bleeding index (mSBI) was 0.08, 0.08, and 0.15 over time. Probing depth (PD) values were 1.57, 1.64, and 2.03 mm. Statistically significant differences were found between 1 vs. 5 year (P = 0.0003) and 3 vs. 5 year (P = 0.001). Keratinized mucosa (3.65 mm) remained stable during observation period. DIB mean values were 2.01 ± 0.34, 2.13 ± 0.13, and 2.17 ± 0.38 mm. Patient satisfaction based on visual analog scale revealed favorable fulfillment of overall treatment and esthetic expectations. Two NDIs supporting a four-unit FDP to replace the four missing maxillary incisors may be considered a predictable treatment modality. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Sandy Hook : alternative access concept plan and vehicle replacement study

DOT National Transportation Integrated Search

2009-06-01

This study addresses two critical issues of concern to the Sandy Hook Unit of Gateway National : Recreational Area: (1) options for alternative access to Sandy Hook during peak summer season, : particularly when the park is closed to private vehicles...

Validation of RAP and/or RAS in hydraulic cement concrete : technical report.

DOT National Transportation Integrated Search

2017-05-01

The increasing maintenance and rehabilitation actions lead to considerable amounts of reclaimed asphalt pavement : (RAP) left in stockpiles in the United States. The possible use of RAP in Portland cement concrete (PCC) as aggregate : replacement not...

Evaluation of Repair Techniques for Impact-Damaged Prestressed Beams

DOT National Transportation Integrated Search

2018-05-01

Collisions between over-height vehicles and bridges occur about 1,000 times per year in the United States. Collision damage to bridges can range from minor to catastrophic, potentially requiring repair or replacement of a bridge beam. For prestressed...

29 CFR 1919.28 - Unit proof tests-cranes and gear accessory thereto.

Code of Federal Regulations, 2013 CFR

2013-07-01

... case of hydraulic cranes, when due to the limitation of pressure it is impossible to lift a load 25... associated with replacements or renewals, may be made with spring or hydraulic balances where dead loads are...

29 CFR 1919.28 - Unit proof tests-cranes and gear accessory thereto.

Code of Federal Regulations, 2012 CFR

2012-07-01

... case of hydraulic cranes, when due to the limitation of pressure it is impossible to lift a load 25... associated with replacements or renewals, may be made with spring or hydraulic balances where dead loads are...

29 CFR 1919.28 - Unit proof tests-cranes and gear accessory thereto.

Code of Federal Regulations, 2014 CFR

2014-07-01

... case of hydraulic cranes, when due to the limitation of pressure it is impossible to lift a load 25... associated with replacements or renewals, may be made with spring or hydraulic balances where dead loads are...

An Integrated, Evidence-Based Approach to Transitioning to Operations: Specifications for Future Replacement Lights on ISS

NASA Technical Reports Server (NTRS)

Leveton, Lauren; Brainard, George; Whitmire, Alexandra; Kubey, Alan; Maida, Jim; Bowen, Charles; Johnston, Smith

2010-01-01

The International Space Station (ISS) currently uses General Luminaire Assemblies (GLAs) as its primary light source. These GLAs are composed of fluorescent lighting and are integrated into the electrical system on Station. Seventy seven of these units are distributed throughout the vehicle, and many of the lights, having reached their lifespan, are no longer functional; while backup panels are available on orbit, it is anticipated that the supplies of fluorescents on the station will be exhausted by 2015. The ISS vehicle office is therefore preparing to replace all of the GLAs, with Solid State Light Assemblies (SSLAs) composed of white Light Emitting Diodes (LEDs). In the Spring of 2010, an announcement for the replacement lights was released. The announcement specified that proposed lighting systems should use LED technology, given certain power draw restrictions and no changes to how the lights are currently controlled (a central on/off switch per node, and a dial to turn on/off and increase brightness on each lighting unit). The replacement lights are to follow current specifications for brightness levels (lux) and color temperature (degrees Kelvin, or K). Reportedly, the lighting on orbit is dim and suboptimal. The average brightness of the lights (given all lights within a node are operational) is 291 lux; by comparison, recommended office lighting ranges from 200 to 500 lux, and daylight ranges on a typical overcast day, consists of 10,000 to 25,000 lux. Representatives from NASA Behavioral Health and Performance Element (BHP) and Human Factors and Habitability identified that maintaining current brightness levels limits visual acuity, work space, and the use of light as a countermeasure for improving circadian entrainment, hastening phase shifting, evoking acute alertness and enhancing performance. Revised lighting specifications are therefore needed to optimize the replacement lights for the ISS.

Iron balance in the red blood cell donor.

PubMed

Brittenham, G M

2005-01-01

Phlebotomy of a unit of blood produces a loss of 200 to 250 mg of iron in haemoglobin. Because of physiological differences in iron balance between women of childbearing age and men, the loss of similar amounts of iron at donation has divergent consequences for committed donors. Women of childbearing age have an increased risk of iron deficiency if they donate more than one unit per year while men are usually able to maintain iron balance while donating four or more units of blood per year. Lack of iron is the most important medical reason for deferral from repeat donation and primarily affects women of childbearing age. Deferral of these women discourages them from further donation and may lead to their loss as donors. Provisions for blood donation should protect those who give blood from adverse consequences of their altruism. Safe and effective approaches to iron replacement after donation have been developed that can prevent iron deficiency in women who give blood repeatedly. Blood centres should consider incorporating programmes of iron replacement for women of childbearing age who give blood repeatedly to protect these donors against iron deficiency and to enhance their retention and commitment as dedicated donors.

A dented LH2 recirculation line is removed from Discovery

NASA Technical Reports Server (NTRS)

1999-01-01

In the Payload Changeout Room, Launch Pad 39B, United Space Alliance and NASA workers look at the replacement main propulsion system liquid hydrogen recirculation line (left) to be installed in Shuttle Discovery's aft compartment. At right is the dented line that has been removed. The 12-inch-long dent was discovered during routine aft compartment inspections Tuesday, Dec. 7. The line recirculates hydrogen from the Shuttle main engines back to the external tank during prelaunch engine conditioning. The line is being replaced and managers expect the replacement work to take about 3 days, followed by system retests and final aft compartment close-outs. Preliminary assessments reflect a launch date of Space Shuttle Discovery on mission STS-103 no earlier than Dec. 16. STS-103 is the third servicing mission for the Hubble Space Telescope.

Maintenance Task Data Base for Buildings: Architectural Systems

DTIC Science & Technology

1991-05-01

EXTERIOR DOOR Task Descriptin REPLACE METAL WIRE MESH PAINTD EEIO DOOR Unit of Measure: CWNT~ Fr enc of ccrence: H: i.~UU A: 15U.UU L: 160.00 Persons...5R.ULA5S:REPL.3RD FL.WD.FR.PAIN.)DL.EX .WIND0WS Unit of Measure: COURT- Freq.. enc OfOcr ee : 0.Yu A: 1.UU L: 1AiI Persons per Team: 1 Task DuRation: 0...System: EXTERIOR WINDOWS Susystem: INOPERABLE WIND)OWS Tak ecrpRtVLACE 2ND FLOOR STEEL FRAME(PAIT ETWINDOWS Unit of Measure: - JN I Frequjeng orOc ence : N

Modernization of Koesters interferometer and high accuracy calibration gauge blocks

NASA Astrophysics Data System (ADS)

França, R. S.; Silva, I. L. M.; Couceiro, I. B.; Torres, M. A. C.; Bessa, M. S.; Costa, P. A.; Oliveira, W., Jr.; Grieneisen, H. P. H.

2016-07-01

The Optical Metrology Division (Diopt) of Inmetro is responsible for maintaining the national reference of the length unit according to International System of Units (SI) definitions. The length unit is realized by interferometric techniques and is disseminated to the dimensional community through calibrations of gauge blocks. Calibration of large gauge blocks from 100 mm to 1000 mm has been performed by Diopt with a Koesters interferometer with reference to spectral lines of a krypton discharge lamp. Replacement of this lamp by frequency stabilized lasers, traceable now to the time and frequency scale, is described and the first results are reported.

KSC-08pd2355

NASA Image and Video Library

2008-08-08

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, workers lift the Fine Guidance Sensor Scientific Instrument Protective Enclosure, or FSIPE, cover before attaching a crane. The cover will be installed on the Orbital Replacement Unit Carrier, or ORUC. The ORUC is one of three carriers that are being prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the fifth and final Hubble servicing mission, STS-125. Launch is targeted for Oct. 8. PHoto credit: NASA/Jack Pfaller

KSC-08pd2356

NASA Image and Video Library

2008-08-08

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, an overhead crane moves the Fine Guidance Sensor Scientific Instrument Protective Enclosure, or FSIPE, cover to be installed on the Orbital Replacement Unit Carrier, or ORUC, below. The ORUC is one of three carriers that are being prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the fifth and final Hubble servicing mission, STS-125. Launch is targeted for Oct. 8. PHoto credit: NASA/Jack Pfaller

Gyre and gimble: a maximum-likelihood replacement for Patterson correlation refinement.

PubMed

McCoy, Airlie J; Oeffner, Robert D; Millán, Claudia; Sammito, Massimo; Usón, Isabel; Read, Randy J

2018-04-01

Descriptions are given of the maximum-likelihood gyre method implemented in Phaser for optimizing the orientation and relative position of rigid-body fragments of a model after the orientation of the model has been identified, but before the model has been positioned in the unit cell, and also the related gimble method for the refinement of rigid-body fragments of the model after positioning. Gyre refinement helps to lower the root-mean-square atomic displacements between model and target molecular-replacement solutions for the test case of antibody Fab(26-10) and improves structure solution with ARCIMBOLDO_SHREDDER.

Phytoestrogens: a viable option?

PubMed

Russell, Lori; Hicks, G Swink; Low, Annette K; Shepherd, Jinna M; Brown, C Andrew

2002-10-01

Estrogen replacement therapy is one of the most commonly prescribed medicines in the United States by traditional medical professionals. Over the past decade, the market for complementary/ alternative therapies for hormone replacement has dramatically increased. Women are seeking more "natural" alternatives to treat menopausal symptoms. Well-designed randomized clinical trials are often lacking, as is the information on efficacy and safety. This article will review several popular herbal therapies for menopausal symptoms including phytoestrogens, black cohosh (Cimicifuga racemosa), dong quai (Angelica sinensis), chast tree (Vitex agnus-castus), and wild Mexican yam. Their use, mechanism of action, and adverse effects are outlined.

KSC-02pd0711

NASA Image and Video Library

2002-05-17

KENNEDY SPACE CENTER, FLA. -- STS-111 Mission Specialist Philippe Perrin gets ready in his launch and entry suit for a simulated launch countdown at the pad. Perrin is with the French Space Agency. The simulation is part of STS-111 Terminal Countdown Demonstration Test activities for the STS-111 crew and Expedition 5. The payload on the mission to the International Space Station includes the Mobile Base System, an Orbital Replacement Unit and Multi-Purpose Logistics Module Leonardo. The Expedition 5 crew is traveling on Endeavour to replace the Expedition 4 crew on the Station. Launch of Endeavour is scheduled for May 30, 2002.

An Examination of the Conceptual Basis of a Tactical, Logistical, and Air Simulation (ATLAS).

DTIC Science & Technology

1980-03-01

guides the simulation from the start. From this scenario and the de - veloping tactical situation comes information which triggers the tactical-decision...effect of tactical aircraft in a combat situation together with the effect of weapons to destroy the aircraft. The presence of transport aircraft is...sector, the ability of that sector to resupply existing combat units, to transport replacement items and supplies, and to move the new unit through

The United States Army Medical Department Journal. The United States Army Dental Corps: A Century of Commitment, Service, and Care

DTIC Science & Technology

2011-03-01

Nerve in US Army 70 Dental Assistants Before and After Training as Preventive Dental Specialists David G. Greathouse, PhD; et al Palatal Fracture in...Command’s Corporate Dental Application (CDA). Originally conceived and developed as a standard solution to replace an array of locally implemented... palatal fracture and displacement of the bone up into the nasal vestibule. Their article carefully describes the unusual circumstances surrounding

Expedition Seven CDR Malenkenko performs IFM on Condensate Water Processor

NASA Image and Video Library

2003-07-03

ISS007-E-09229 (3 July 2003) --- Cosmonaut Yuri I. Malenchenko, Expedition 7 mission commander, performs scheduled in-flight maintenance (IFM) on the condensate water processor (SRV-K2M) by removing and replacing its BKO multifiltration/purification column unit, which has reached its service life limit (450 liters min.). The old unit will be discarded on Progress. The IFM took place in the Zvezda Service Module on the International Space Station (ISS). Malenchenko represents Rosaviakosmos.

Expedition Seven CDR Malenkenko performs IFM on Condensate Water Processor

NASA Image and Video Library

2003-07-03

ISS007-E-09231 (3 July 2003) --- Cosmonaut Yuri I. Malenchenko, Expedition 7 mission commander, performs scheduled in-flight maintenance (IFM) on the condensate water processor (SRV-K2M) by removing and replacing its BKO multifiltration/purification column unit, which has reached its service life limit (450 liters min.). The old unit will be discarded on Progress. The IFM took place in the Zvezda Service Module on the International Space Station (ISS). Malenchenko represents Rosaviakosmos.

Final Environmental Planning Technical Report. Public Services and Facilities

DTIC Science & Technology

1984-06-01

The marked patrol units have a life expectancy of 2 years (90,000 to 100,000 miles) and about one-half of the 15 units are replaced each year...much more visible police force, longer car life , and lower maintenance costs. The proposal has received support from within the City government, but...Burns, Albin, and Carpenter; the Air Force Military Assistance to Safety and Traffic (MAST) helicopter service; Flight for Life ; and several other suppor

Neurodynamical model of collective brain

NASA Technical Reports Server (NTRS)

Zak, Michail

1992-01-01

A dynamical system which mimics collective purposeful activities of a set of units of intelligence is introduced and discussed. A global control of the unit activities is replaced by the probabilistic correlations between them. These correlations are learned during a long term period of performing collective tasks, and are stored in the synaptic interconnections. The model is represented by a system of ordinary differential equations with terminal attractors and repellers, and does not contain any man-made digital devices.

Toxicological Outcomes in Rats Exposed to Inhaled Ethanol During Gestation

EPA Science Inventory

Recent legislation has encouraged replacing petroleum-based fuels with renewable alternatives including ethanol, which is currently blended with gasoline in the United States at concentrations up to 15%. Efforts to increase the amount of ethanol in gasoline have prompted concerns...

77 FR 66824 - City of Holyoke Gas and Electric Department; Notice of Application Accepted for Filing...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-07

... fishlift entrance. The licensee further proposes to do an in-kind replacement of the Hadley Unit 1 turbine... capacity by 600 kilowatts, and increase the maximum hydraulic capacity by an estimated 320 cubic feet per...

77 FR 38608 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-28

..., professional qualifications and skills, training courses completed, certifications received, level of education... Activity Unit Identification Code (UIC).'' Safeguards: Delete entry and replace with ``The NTMPS servers.... All data transferred is encrypted. The interface server is protected from attempts to penetrate the...

Fuel consumption of ADS-B and non-ADS-B helicopter operation in the Gulf of Mexico

DOT National Transportation Integrated Search

2013-07-01

Automatic Dependent Surveillance Broadcast (ADSB) is a key enabling technology for the Next Generation Air Transportation System (NextGen) in the United States. The NextGen system replaces the current ground based commandandcontrol syste...

Transport, speciation, toxicity, and treatability of highway stormwater discharged to receiving waters in Louisiana : [tech summary].

DOT National Transportation Integrated Search

2013-01-01

As centralized wastewater treatment continues to improve while increasingly replacing decentralized systems, urban : rainfall-runoff has become the leading contributor of water body impairments in the United States (USEPA, 1996). For : many water bod...

ASI: Dunaliella Marine Microalgae to Drop-In Replacement Liquid Transportation Fuel

USDA-ARS?s Scientific Manuscript database

Microalgae are a promising biofuels feedstock, theoretically yielding concentrations of triacylglycerides (TAGs) per unit area far higher than traditional feedstocks due to their rapid growth. Dunaliella is particularly advantageous as a feedstock because it is currently commercially mass cultured,...

Finite element modeling approach and performance evaluation of fiber reinforced polymer sandwich bridge panels : summary.

DOT National Transportation Integrated Search

2009-08-01

In the United States, about 27% of the bridges are classified as structurally deficient or functionally obsolete. Bridge owners are continually investigating methods to effectively retrofit existing bridges, or to economically replace them with new o...

User delay costs due to work zone operations Near Echo Junction.

DOT National Transportation Integrated Search

2010-11-01

With the increasing number of road rehabilitation projects across the United States, the need to reduce user costs due to congestion is more important than ever. The Utah Department of Transportation (UDOT) has proposed replacing two I-80 bridges ove...

Finite element modeling approach and performance evaluation of fiber reinforced polymer sandwich bridge panels : final report.

DOT National Transportation Integrated Search

2009-08-01

In the United States, about 27% of the bridges are classified as structurally deficient or functionally obsolete. : Bridge owners are continually investigating methods to effectively retrofit existing bridges, or to economically replace : them with n...

77 FR 22760 - Proposed Information Collection; Comment Request; Southeast Region Gulf of Mexico Electronic...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-17

... electronic logbook memory chip will be removed from the unit and downloaded at the contractor site in College Station, Texas. A new logbook memory chip will replace the removed memory chip, a process taking less than...

Steel pin and hanger assembly replacement options : final report.

DOT National Transportation Integrated Search

2017-01-01

A number of steel beam bridges exist in the United States that contain pin and hanger assemblies. Pin and hanger assemblies are fracture critical members whose failure would result in collapse of the bridge or render it unable to perform its expected...

An analysis of student programmatic delays in postsecondary flight training programs : a national study

DOT National Transportation Integrated Search

1996-01-01

Since the passage of the Airline Deregulation Act (ADA) in 1978, the need for professionally--trained air carrier pilots in the United States has expanded substantially. Postsecondary academic institutions have replaced the military as a major source...

Evaluation of repair techniques for impact-damaged prestressed beams : final report.

DOT National Transportation Integrated Search

2017-04-01

Collisions between over height vehicles and bridges occur about 1,000 times per year in the United States. Collision damage to : bridges can range from minor to catastrophic, potentially requiring repair or replacement of a bridge beam. For prestress...

Complications from prophylactic replacement of cardiac implantable electronic device generators in response to United States Food and Drug Administration recall: A systematic review and meta-analysis.

PubMed

Zeitler, Emily P; Patel, Divyang; Hasselblad, Vic; Sanders, Gillian D; Al-Khatib, Sana M

2015-07-01

The number of cardiac implantable electronic device (CIED) recalls and advisories has increased over the past 3 decades, yet no consensus exists on how to best manage patients with these CIEDs, partially because rates of complications from prophylactic replacement are unknown. The purpose of this study was to establish rates of complications when recalled CIED generators are replaced prophylactically. We searched MEDLINE and the Cochrane Controlled Trials Register for reports of prophylactic replacement of recalled CIED generators. Studies with <20 subjects were excluded. We then conducted a meta-analysis of qualifying studies to determine the rates of combined major complications, mortality, and reoperation. We identified 7 citations that met our inclusion criteria and reported ≥1 end-points of interest. Four were single center, and 3 were multicenter. Six studies collected data retrospectively (n = 1213) and 1 prospectively (n = 222). Using a random effects model to combine data from all included studies, the rate of major complications was 2.5% (95% confidence interval [CI] 1.0%-4.5%). Combining data from 6 studies reporting mortality and reoperation, the rates were 0.5% (95% CI 0.1%-0.9%) and 2.5% (95% CI 0.8%-4.5%), respectively. Prophylactic replacement of recalled CIED generators is associated with a low mortality rate but nontrivial rates of other major complications similar to those reported when CIED generators are replaced for other reasons. Thus, when considering replacing a recalled CIED generator, known risks of elective generator replacement likely apply and can be weighed against risks associated with device failure. Copyright © 2015 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

Urine output on an intensive care unit: case-control study.

PubMed

Solomon, Anthony W; Kirwan, Christopher J; Alexander, Neal D E; Nimako, Kofi; Jurukov, Angela; Forth, Rebecca J; Rahman, Tony M

2010-12-14

To compare urine output between junior doctors in an intensive care unit and the patients for whom they are responsible. Case-control study. General intensive care unit in a tertiary referral hospital. 18 junior doctors responsible for clerking patients on weekday day shifts in the unit from 23 March to 23 April 2009 volunteered as "cases." Controls were the patients in the unit clerked by those doctors. Exclusion criteria (for both groups) were pregnancy, baseline estimated glomerular filtration rate <15 ml/min/1.73 m(2), and renal replacement therapy. Oliguria (defined as mean urine output <0.5 ml/kg/hour over six or more hours of measurement) and urine output (in ml/kg/hour) as a continuous variable. Doctors were classed as oliguric and "at risk" of acute kidney injury on 19 (22%) of 87 shifts in which urine output was measured, and oliguric to the point of being "in injury" on one (1%) further shift. Data were available for 208 of 209 controls matched to cases in the data collection period; 13 of these were excluded because the control was receiving renal replacement therapy. Doctors were more likely to be oliguric than their patients (odds ratio 1.99, 95% confidence interval 1.08 to 3.68, P=0.03). For each additional 1 ml/kg/hour mean urine output, the odds ratio for being a case rather than a control was 0.27 (0.12 to 0.58, P=0.001). Mortality among doctors was astonishingly low, at 0% (0% to 18%). Managing our own fluid balance is more difficult than managing it in our patients. We should drink more water. Modifications to the criteria for acute kidney injury could be needed for the assessment of junior doctors in an intensive care unit.

How to treat two adjacent missing teeth with dental implants. A systematic review on single implant-supported two-unit cantilever FDP's and results of a 5-year prospective comparative study in the aesthetic zone.

PubMed

Van Nimwegen, W G; Raghoebar, G M; Tymstra, N; Vissink, A; Meijer, H J A

2017-06-01

To conduct a systematic review on the clinical outcome of single implant-supported two-unit cantilever FDP's and to conduct a 5-year prospective comparative pilot study of patients with a missing central and lateral upper incisor treated with either a single implant-supported two-unit cantilever FDP or two implants with solitary implant crowns in the aesthetic zone. Medline, Embase and the Cochrane Central Register of Controlled Trials were searched (last search 1 August 2016) for eligible studies. In the comparative pilot study, an implant-cantilever group of five patients with a single implant-supported two-unit cantilever FDP (NobelReplace Groovy Regular Platform) was compared with an implant-implant group of five patients with two adjacent single implant-supported crowns (NobelReplace Groovy Regular Platform) in the aesthetic zone. Implant survival, marginal bone level (MBL) changes, pocket probing depth, papilla index and patient satisfaction were assessed during a 5-year follow-up period. Five of 276 articles were considered eligible for data extraction. Implant survival ranged from 96·6% to 100%. Marginal bone level changes were higher in the anterior region than in the posterior region. Technical complications occurred more often in the posterior than anterior region. In the 5-year comparative pilot study, no clinically significant differences in hard and soft peri-implant tissue levels occurred between both groups. Single implant-supported two-unit cantilever FDP's can be a viable alternative to the placement of two adjacent single implant crowns in the aesthetic zone. Due to technical complications, placement of two-unit cantilever crowns in the posterior region can be considered unwise. © 2017 John Wiley & Sons Ltd.

Wide Field Camera 3 Accommodations for HST Robotics Servicing Mission

NASA Technical Reports Server (NTRS)

Ginyard, Amani

2005-01-01

This slide presentation discusses the objectives of the Hubble Space Telescope (HST) Robotics Servicing and Deorbit Mission (HRSDM), reviews the Wide Field Camera 3 (WFC3), and also reviews the contamination accomodations for the WFC3. The objectives of the HRSDM are (1) to provide a disposal capability at the end of HST's useful life, (2) to upgrade the hardware by installing two new scientific instruments: replace the Corrective Optics Space Telescope Axial Replacement (COSTAR) with the Cosmic Origins Spectrograph (COS), and to replace the Wide Field/Planetary Camera-2 (WFPC2) with Wide Field Camera-3, and (3) Extend the Scientific life of HST for a minimum of 5 years after servicing. Included are slides showing the Hubble Robotic Vehicle (HRV) and slides describing what the HRV contains. There are also slides describing the WFC3. One of the mechanisms of the WFC3 is to serve partially as replacement gyroscopes for HST. There are also slides that discuss the contamination requirements for the Rate Sensor Units (RSUs), that are part of the Rate Gyroscope Assembly on the WFC3.

Clustered atom-replaced structure in single-crystal-like metal oxide

NASA Astrophysics Data System (ADS)

Araki, Takeshi; Hayashi, Mariko; Ishii, Hirotaka; Yokoe, Daisaku; Yoshida, Ryuji; Kato, Takeharu; Nishijima, Gen; Matsumoto, Akiyoshi

2018-06-01

By means of metal organic deposition using trifluoroacetates (TFA-MOD), we replaced and localized two or more atoms in a single-crystalline structure having almost perfect orientation. Thus, we created a new functional structure, namely, clustered atom-replaced structure (CARS), having single-crystal-like metal oxide. We replaced metals in the oxide with Sm and Lu and localized them. Energy dispersive x-ray spectroscopy results, where the Sm signal increases with the Lu signal in the single-crystalline structure, confirm evidence of CARS. We also form other CARS with three additional metals, including Pr. The valence number of Pr might change from 3+ to approximately 4+, thereby reducing the Pr–Ba distance. We directly observed the structure by a high-angle annular dark-field image, which provided further evidence of CARS. The key to establishing CARS is an equilibrium chemical reaction and a combination of additional larger and smaller unit cells to matrix cells. We made a new functional metal oxide with CARS and expect to realize CARS in other metal oxide structures in the future by using the above-mentioned process.

Ultra Reliable Closed Loop Life Support for Long Space Missions

NASA Technical Reports Server (NTRS)

Jones, Harry W.; Ewert, Michael K.

2010-01-01

Spacecraft human life support systems can achieve ultra reliability by providing sufficient spares to replace all failed components. The additional mass of spares for ultra reliability is approximately equal to the original system mass, provided that the original system reliability is not too low. Acceptable reliability can be achieved for the Space Shuttle and Space Station by preventive maintenance and by replacing failed units. However, on-demand maintenance and repair requires a logistics supply chain in place to provide the needed spares. In contrast, a Mars or other long space mission must take along all the needed spares, since resupply is not possible. Long missions must achieve ultra reliability, a very low failure rate per hour, since they will take years rather than weeks and cannot be cut short if a failure occurs. Also, distant missions have a much higher mass launch cost per kilogram than near-Earth missions. Achieving ultra reliable spacecraft life support systems with acceptable mass will require a well-planned and extensive development effort. Analysis must determine the reliability requirement and allocate it to subsystems and components. Ultra reliability requires reducing the intrinsic failure causes, providing spares to replace failed components and having "graceful" failure modes. Technologies, components, and materials must be selected and designed for high reliability. Long duration testing is needed to confirm very low failure rates. Systems design should segregate the failure causes in the smallest, most easily replaceable parts. The system must be designed, developed, integrated, and tested with system reliability in mind. Maintenance and reparability of failed units must not add to the probability of failure. The overall system must be tested sufficiently to identify any design errors. A program to develop ultra reliable space life support systems with acceptable mass should start soon since it must be a long term effort.

STS-109 Onboard Photo of Extra-Vehicular Activity (EVA)

NASA Technical Reports Server (NTRS)

2002-01-01

This is an onboard photo of Astronaut John M. Grunsfield, STS-109 payload commander, participating in the third of five spacewalks to perform work on the Hubble Space Telescope (HST). On this particular walk, Grunsfield, joined by Astronaut Richard M. Lirnehan, turned off the telescope in order to replace its power control unit (PCU), the heart of the HST's power system. The telescope was captured and secured on a work stand in Columbia's payload bay using Columbia's robotic arm, where crew members completed system upgrades to the HST. Included in those upgrades were: replacement of the solar array panels; replacement of the power control unit (PCU); replacement of the Faint Object Camera (FOC) with a new advanced camera for Surveys (ACS); and installation of the experimental cooling system for the Hubble's Near-Infrared Camera and Multi-object Spectrometer (NICMOS), which had been dormant since January 1999 when its original coolant ran out. The Marshall Space Flight Center had the responsibility for the design, development, and construction of the HST, which is the most complex and sensitive optical telescope ever made, to study the cosmos from a low-Earth orbit. The HST detects objects 25 times fainter than the dimmest objects seen from Earth and provides astronomers with an observable universe 250 times larger than is visible from ground-based telescopes, perhaps as far away as 14 billion light-years. The HST views galaxies, stars, planets, comets, possibly other solar systems, and even unusual phenomena such as quasars, with 10 times the clarity of ground-based telescopes. Launched March 1, 2002 the STS-109 HST servicing mission lasted 10 days, 22 hours, and 11 minutes. It was the 108th flight overall in NASA's Space Shuttle Program.

Space Shuttle Projects

NASA Image and Video Library

2002-03-06

This is an onboard photo of Astronaut John M. Grunsfield, STS-109 payload commander, participating in the third of five spacewalks to perform work on the Hubble Space Telescope (HST). On this particular walk, Grunsfield, joined by Astronaut Richard M. Lirnehan, turned off the telescope in order to replace its power control unit (PCU), the heart of the HST's power system. The telescope was captured and secured on a work stand in Columbia's payload bay using Columbia's robotic arm, where crew members completed system upgrades to the HST. Included in those upgrades were: replacement of the solar array panels; replacement of the power control unit (PCU); replacement of the Faint Object Camera (FOC) with a new advanced camera for Surveys (ACS); and installation of the experimental cooling system for the Hubble's Near-Infrared Camera and Multi-object Spectrometer (NICMOS), which had been dormant since January 1999 when its original coolant ran out. The Marshall Space Flight Center had the responsibility for the design, development, and construction of the HST, which is the most complex and sensitive optical telescope ever made, to study the cosmos from a low-Earth orbit. The HST detects objects 25 times fainter than the dimmest objects seen from Earth and provides astronomers with an observable universe 250 times larger than is visible from ground-based telescopes, perhaps as far away as 14 billion light-years. The HST views galaxies, stars, planets, comets, possibly other solar systems, and even unusual phenomena such as quasars, with 10 times the clarity of ground-based telescopes. Launched March 1, 2002 the STS-109 HST servicing mission lasted 10 days, 22 hours, and 11 minutes. It was the 108th flight overall in NASA's Space Shuttle Program.

STS-61 Space Shuttle mission report

NASA Technical Reports Server (NTRS)

Fricke, Robert W., Jr.

1994-01-01

The STS-61 Space Shuttle Program Mission Report summarizes the Hubble Space Telescope (HST) servicing mission as well as the Orbiter, External Tank (ET), Solid Rocket Booster (SRB), Redesigned Solid Rocket Motor (RSRM), and the Space Shuttle main engine (SSME) systems performance during the fifty-ninth flight of the Space Shuttle Program and fifth flight of the Orbiter vehicle Endeavour (OV-105). In addition to the Orbiter, the flight vehicle consisted of an ET designated as ET-60; three SSME's which were designated as serial numbers 2019, 2033, and 2017 in positions 1, 2, and 3, respectively; and two SRB's which were designated BI-063. The RSRM's that were installed in each SRB were designated as 360L023A (lightweight) for the left SRB, and 360L023B (lightweight) for the right SRB. This STS-61 Space Shuttle Program Mission Report fulfills the Space Shuttle Program requirement as documented in NSTS 07700, Volume 8, Appendix E. That document requires that each major organizational element supporting the Program report the results of its hardware evaluation and mission performance plus identify all related in-flight anomalies. The primary objective of the STS-61 mission was to perform the first on-orbit servicing of the Hubble Space Telescope. The servicing tasks included the installation of new solar arrays, replacement of the Wide Field/Planetary Camera I (WF/PC I) with WF/PC II, replacement of the High Speed Photometer (HSP) with the Corrective Optics Space Telescope Axial Replacement (COSTAR), replacement of rate sensing units (RSU's) and electronic control units (ECU's), installation of new magnetic sensing systems and fuse plugs, and the repair of the Goddard High Resolution Spectrometer (GHRS). Secondary objectives were to perform the requirements of the IMAX Cargo Bay Camera (ICBC), the IMAX Camera, and the Air Force Maui Optical Site (AMOS) Calibration Test.

Automated Coal-Mine Shuttle Car

NASA Technical Reports Server (NTRS)

Collins, E. R., Jr.

1984-01-01

Cable-guided car increases efficiency in underground coal mines. Unmanned vehicle contains storage batteries in side panels for driving traction motors located in wheels. Batteries recharged during inactive periods or slid out as unit and replaced by fresh battery bank. Onboard generator charges batteries as car operates.

Resource Allocation--The Case of the Australian National University.

ERIC Educational Resources Information Center

Jackson, G. W.

1982-01-01

A historical, incremental method for allocating resources in the Institute for Advanced Studies in recent years is being replaced by a new approach involving the identification of purposes and pursuits and evaluation of their importance. Greater responsiveness to unit needs is the objective. (MSE)

75 FR 57745 - FPL Energy Maine Hydro LLC; Notice of Application for Amendment of License and Soliciting...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-22

... Unit 3 of the project by rewinding the generator and replacing the turbine runner with a more efficient runner. The proposed upgrade would increase the installed and hydraulic capacities of the project by 5.7...

Load beam unit replaceable inserts for dry coal extrusion pumps

DOEpatents

Saunders, Timothy; Brady, John D.

2012-11-13

A track assembly for a particulate material extrusion pump according to an exemplary aspect of the present disclosure includes a link assembly with a roller bearing. An insert mounted to a load beam located such that the roller bearing contacts the insert.

Operations analysis (study 2.1). Payload designs for space servicing, addendum

NASA Technical Reports Server (NTRS)

Wolfe, R. R.

1974-01-01

Space replaceable units and payload configurations are revised to reflect increased levels of redundancy to be more consistent with current design practices. A reassessment of expendable payload design reliabilities was performed to provide a common basis for comparison with space serviceable configurations.

Hopkins in the A/L

NASA Image and Video Library

2013-12-18

View of Mike Hopkins, Expedition 38 Flight Engineer (FE), during remove and replace (R&R) of Hard Upper Torso (HUT) of Extravehicular Mobility Unit (EMU), in the airlock (A/L) during preparation for EVA-24. Photo was taken during Expedition 38. Image was released by astronaut on Twitter.

Conversion between network-level and project-level units of measure for use in a bridge-management system.

DOT National Transportation Integrated Search

1998-01-01

VDOT is implementing Pontis 3.0 to provide the analytical component of its Bridge Management System (BMS). This system prioritizes bridge maintenance, repair, rehabilitation, and replacement (MRR & R) needs using cost/benefit analysis. The accuracy o...

7 CFR 654.2 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... period for which project or measure benefits and costs have been evaluated. The evaluated life starts after the last project measure of the evaluation unit has been completed. Landuser. Those who... purpose and the replacement of portions of project measures as specified in the O&M agreement. Operation...

The role of flight progress strips in en route air traffic control : a time-series analysis.

DOT National Transportation Integrated Search

1995-01-01

Paper flight progress strips (FPSs) are currently used in the United States en route air traffic control system to document flight information. Impending automation will replace these paper strips with electronic flight data entries. In this observat...

Carbon offsets from improved swine manure management using aerobic treatment technology

USDA-ARS?s Scientific Manuscript database

Aerobic treatment of manure is an accepted manure management system under protocols adopted through the United Nations Framework Convention on Climate Change (UNFCCC). Our objectives were to determine greenhouse gas (GHG) emission reductions from replacement of anaerobic lagoons with aerobic treatme...

Orbiter Auxiliary Power Unit Flight Support Plan

NASA Technical Reports Server (NTRS)

Guirl, Robert; Munroe, James; Scott, Walter

1990-01-01

This paper discussed the development of an integrated Orbiter Auxiliary Power Unit (APU) and Improved APU (IAPU) Flight Suuport Plan. The plan identifies hardware requirements for continued support of flight activities for the Space Shuttle Orbiter fleet. Each Orbiter vehicle has three APUs that provide power to the hydraulic system for flight control surface actuation, engine gimbaling, landing gear deployment, braking, and steering. The APUs contain hardware that has been found over the course of development and flight history to have operating time and on-vehicle exposure time limits. These APUs will be replaced by IAPUs with enhanced operating lives on a vehicle-by-vehicle basis during scheduled Orbiter modification periods. This Flight Support Plan is used by program management, engineering, logistics, contracts, and procurement groups to establish optimum use of available hardware and replacement quantities and delivery requirements for APUs until vehicle modifications and incorporation of IAPUs. Changes to the flight manifest and program delays are evaluated relative to their impact on hardware availability.

An electric artificial heart for clinical use.

PubMed Central

Pierce, W S; Rosenberg, G; Snyder, A J; Pae, W E; Donachy, J H; Waldhausen, J A

1990-01-01

Advances in microelectronics, high-strength magnets, and control system design now make replacement of the heart using an implantable, electrically powered pump feasible. The device described herein is a compact, dual pusher plate unit with valved polyurethane sac-type ventricles positioned at either end. The power unit consists of a small, brushless direct current motor and a motion translator. A microprocessor control system is used to regulate heart beat rate and provide left-right output balance. Bench studies lasting for as long as 1 year have been performed. Heart replacement with the electric heart has been performed in 18 calves since 1984. The longest survivor lived for more than 7 months. Among the causes of termination were component failure, thromboembolic complications, and bleeding. No major problem has been identified that precludes prolonged use of the electric heart. In the future the patient with end-stage heart disease will have an electric artificial heart as one therapeutic option. Images Figs. 1A and 1B. Fig. 3. Fig. 5. PMID:2396885

Development of 10B-Based 3He Replacement Neutron Detectors

NASA Astrophysics Data System (ADS)

King, Michael J.; Gozani, Tsahi; Hilliard, Donald B.

2011-12-01

Radiation portal monitors (RPM) are currently deployed at United States border crossings to passively inspect vehicles and persons for any emission of neutrons and/or gamma rays, which may indicate the presence of unshielded nuclear materials. The RPM module contains an organic scintillator with 3He proportional counters to detect gamma rays and thermalized neutrons, respectively. The supply of 3He is rapidly dwindling, requiring alternative detectors to provide the same function and performance. Our alternative approach is one consisting of a thinly-coated 10B flat-panel ionization chamber neutron detector that can be deployed as a direct drop-in replacement for current RPM 3He detectors. The uniqueness of our approach in providing a large-area detector is in the simplicity of construction, scalability of the unit cell detector, ease of adaptability to a variety of applications and low cost. Currently, Rapiscan Laboratories and Helicon Thin Film Systems have designed and developed an operational 100 cm2 multi-layer prototype 10BB-based ionization chamber.

Crystallization, X-ray diffraction analysis and preliminary structure determination of the polygalacturonase PehA from Agrobacterium vitis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vordtriede, Paul B.; Yoder, Marilyn D., E-mail: yoderm@umkc.edu

2008-07-01

The acidic polygalacturonase PehA from A. vitis has been crystallized. A molecular-replacement solution indicated a right-handed parallel β-helix fold. Polygalacturonases are pectate-degrading enzymes that belong to glycoside hydrolase family 28 and hydrolyze the α-1,4 glycosidic bond between neighboring galacturonasyl residues of the homogalacturonan substrate. The acidic polygalacturonase PehA from Agrobacterium vitis was overexpressed in Escherichia coli, where it accumulated in the periplasmic fraction. It was purified to homogeneity via a two-step chromatography procedure and crystallized using the hanging-drop vapour-diffusion technique. PehA crystals belonged to space group P2{sub 1}, with unit-cell parameters a = 52.387, b = 62.738, c = 149.165more » Å, β = 89.98°. Crystals diffracted to 1.59 Å resolution and contained two molecules per asymmetric unit. An initial structure determination by molecular replacement indicated a right-handed parallel β-helix fold.« less

Crystallization and preliminary X-ray diffraction studies of NP24-I, an isoform of a thaumatin-like protein from ripe tomato fruits

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ghosh, Raka; Chakrabarti, Chandana, E-mail: chandana.chakrabarti@saha.ac.in

2005-08-01

A thaumatin-like antifungal protein, NP24-I, has been isolated from ripe tomato fruits. It was crystallized by the vapour-diffusion method and data were collected to 2.45 Å. The structure was solved by molecular replacement. NP24 is a 24 kDa (207-amino-acid) antifungal thaumatin-like protein (TLP) found in tomato fruits. An isoform of the protein, NP24-I, is reported to play a possible role in ripening of the fruit in addition to its antifungal properties. The protein has been isolated and purified and crystallized by the hanging-drop vapour-diffusion method. The crystals belong to the tetragonal space group P4{sub 3}, with unit-cell parameters a =more » b = 61.01, c = 62.90 Å and one molecule per asymmetric unit. X-ray diffraction data were processed to a resolution of 2.45 Å and the structure was solved by molecular replacement.« less

The effect of fish meal replacement by soyabean products on fish growth: a meta-analysis.

PubMed

Sales, James

2009-12-01

Meta-analysis was applied to quantify the effect of replacement of fish meal by soyabean products in diets on fish growth. Measurement of growth in different units among studies required the use of a standardised effect size (Hedges' d). From a total of ninety-nine studies concentrating on fish meal replacement by defatted soyabean meal, 53 % were eliminated due to, among others, absence of a fish meal control diet (n 18), or no statistical differences or measurement of dispersion (n 6) indicated. Replacement of 4 to 40 % fish meal by soyabean meal (inclusion levels of 71-366 g/kg) resulted in a mean effect size of - 0.1142 (95 % CI - 0.4665, 0.2382) obtained in forty-eight comparisons evaluated with seventeen different fish species. However, at higher fish meal replacement levels the 95 % CI calculated for combined effect sizes did not overlap with zero. With soya protein concentrate replacing 25 to 100 % of fish meal in diets for seven fish species, methionine supplementation (mean - 2.4373 (95 % CI - 3.9004, - 0.9742); n 10) did not have a substantial influence on the magnitude of cumulative effect sizes relative to no supplementation (mean - 2.7306 (95 % CI - 3.7991, - 1.6620); n 16). Information on other soyabean products (full-fat soyabeans, soya flour) used as protein sources in fish diets was found as too limited for analysis and definite conclusions. The present study contributes by putting a numerical value to the magnitude of growth differences in fish when replacing dietary fish meal by soyabean products.

Collaborative study for the calibration of a replacement International Standard for Tetanus Toxoid Adsorbed.

PubMed

Tierney, Rob; Stickings, Paul; Hockley, Jason; Rigsby, Peter; Iwaki, Masaaki; Sesardic, Dorothea

2011-11-01

We present the results of a collaborative study for the establishment of a replacement International Standard (IS) for Tetanus Toxoid Adsorbed. Two candidate preparations were included in the study, one of which was established as the 4th IS for Tetanus Toxoid Adsorbed at the WHO Expert Committee on Biological Standardization meeting in October 2010. This preparation was found to have a unitage of 490 IU/ampoule, based on calibration in guinea pig challenge assays. Results from mouse challenge assays suggest that the relative performance of two candidate preparations may differ significantly between guinea pigs and mice. The authors note that the number of laboratories that performed guinea pig challenge assays, which are used to calibrate and assign IU, is much lower than in previous collaborative studies and this may have implications for calibration of replacement standards in the future. The issue of assigning separate units to the IS for guinea pig and mouse assays is discussed. The study also assessed performance of the replacement standard in serological assays which are used as alternative procedures to challenge assays for tetanus potency testing. Results suggest that the replacement standard is suitable for use as the reference vaccine in serological assays. Copyright © 2011 The International Alliance for Biological Standardization. Published by Elsevier Ltd. All rights reserved.

Acoustical renovation of temporary classrooms to meet American National Standards Institute (ANSI) standard

NASA Astrophysics Data System (ADS)

Lubman, David

2005-09-01

This exercise demonstrates that key requirements of the ANSI S12.60-2002 on classroom acoustics can be met through renovations at modest cost. Free-standing classrooms at two schools in Southern California were successfully renovated. Noise levels were greatly reduced, and now meet requirements of the ANSI standard. A 1950s style bungalow classroom at the Paradise Canyon School (PCS) in Los Angeles County and a double-trailer classroom at the Wildomar Elementary School (WES) in Riverside County were targeted. The aim was to make classrooms suitable for pupils with severe hearing disabilities. But the methods used apply equally to mainstream classrooms. At both schools the above-ceiling air distribution systems were modified to produce quiet airflow. At PCS, a noisy rooftop heat pump was replaced with a much quieter rooftop heat pump and installation. At WES, a noisy wall-mounted heat pump was replaced with a new unit mounted on an exterior concrete pad. At PCS, exterior noise intrusion was achieved by replacing a poorly performing accordion wall with a permanent wall. Further noise reduction can be achieved by replacing leaky windows. Exterior noise intrusion at WES was obtained by replacing leaky windows. The resulting acoustical improvements are documented. Costs and lessons learned are discussed.

STS-109 Crew Interviews - Linnehan

NASA Technical Reports Server (NTRS)

2002-01-01

STS-109 Mission Specialist 3 (MS3) Richard M. Linnehan is seen during a prelaunch interview. He answers questions about his lifelong desire to become an astronaut and his career path, which included becoming a zoo veterinarian. He gives details on the Columbia Orbiter mission, which has as its main purpose the maintenance and augmentation of the Hubble Space Telescope (HST). As MS3, his primary role in the mission pertains to EVAs (Extravehicular Activities) 1, 3, and 5. During EVA 1, Linnehan and another crewmember will replace one of two flexible solar arrays on the HST with a smaller, more efficient rigid solar array. The second solar array will be replaced on EVA 2 by other crewmembers. EVA 3 will involve the replacement of the Power Control Unit (PCU), and will require the first complete powering down of HST since its deployment. The possibility of a serious problem occurring is greatest during this portion of the mission because the original PCU was not built to be replaced. In EVA 5, Linnehan and another crewmember will install a replacement cooling system on NICMOS (Near Infrared Camera Multi-Object Spectrometer), which has not been operational. Linnehan discusses his role during the mission as well as that of his crewmates, and provides an abbreviated timeline, including possible contingencies.

Greenhouse gas emissions from the treatment of household plastic containers and packaging: replacement with biomass-based materials.

PubMed

Yano, Junya; Hirai, Yasuhiro; Sakai, Shin-ichi; Tsubota, Jun

2014-04-01

The purpose of this study was to quantify the life-cycle greenhouse gas (GHG) emissions reduction that could be achieved by replacement of fossil-derived materials with biodegradable, biomass-based materials for household plastic containers and packaging, considering a variety of their treatment options. The biomass-based materials were 100% polylactide or a combination of polybutylene succinate adipate and polylactide. A scenario analysis was conducted considering alternative recycling methods. Five scenarios were considered: two for existing fossil-derived materials (the current approach in Japan) and the three for biomass-based materials. Production and waste disposal of 1 m(3) of plastic containers and packaging from households was defined as the functional unit. The results showed that replacement of fossil-derived materials with biomass-based materials could reduce life-cycle GHG emissions by 14-20%. Source separation and recycling should be promoted. When the separate collection ratio reached 100%, replacement with biomass-based materials could potentially reduce GHG emissions by 31.9%. Food containers are a priority for replacement, because they alone could reduce GHG emissions by 10%. A recycling system for biomass-based plastics must be carefully designed, considering aspects such as the transition period from fossil-derived plastics to biomass-based plastics.

A Year in the Life of a Contaminated Heater-Cooler Unit With Mycobacterium chimaera?

PubMed

Garvey, Mark I; Bradley, Craig W; Walker, Jimmy

2017-06-01

OBJECTIVE Heater-cooler units (HCUs) have been shown to be a source of Mycobacterium chimaera infections. For the past year, weekly water samples have been taken from HCUs used at University Hospitals Birmingham (UHB) NHS Foundation Trust. We report the microbial contamination of the HCUs over a year detailing the decontamination regimes applied at UHB to reduce the microbial load. DESIGN Observational study SETTING UHB is a tertiary referral teaching hospital in Birmingham, United Kingdom, that provides clinical services to nearly 1 million patients every year. The UHB Cardiac department is one of the largest in the United Kingdom and provides treatment for adult patients with a wide range of cardiac diseases. METHODS Water samples taken from HCUs used at UHB for cardiopulmonary bypass surgery were sampled over a year to determine the number of microorganisms by membrane filtration. Various decontamination processes were employed throughout the year. RESULTS Varying total viable counts containing a wide variety of microorganisms were obtained from water inside the HCUs. No M. chimaera were isolated after replacement of the HCU internal tubing. Stringent decontamination regimes resulted in degradation of the HCUs and increased TVCs after several months. CONCLUSION More work is required to ensure effective decontamination processes to reduce the microbial load within the HCUs. Our studies indicate that weekly water sampling for TVC will be required indefinitely to monitor the water quality in these units as well as regular replacement of the tubing to control the build-up of biofilm. Infect Control Hosp Epidemiol 2017;38:705-711.

Thermal oxidation saves $500,000, lifts capacity, upholds compliance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harley, C.G.; Nagy, A.J.; Sendecki, M.

1985-12-01

The age and destruction of the heat recovery system dictated the replacement of the original fume incinerator at the Congoleum Resilient Flooring Division Plant in Trenton, NJ. The original unit, installed in 1967, had a conventional air-to-oil heat recovery system. Plant personnel placed high priority on finding a replacement with a higher thermal efficiency while still maintaining environmental integrity. A proprietary software program was used to obtain values for NPV (net pressure value) for several competitive equipment systems. The NPV allows simple comparison of equipment based on data such as purchase pgsrice, cost of installation, operating costs, and maintenance costsmore » for the predicted life span of each unit. Based on NPV analysis, a regenerative thermal oxidation unit was selected. To assure expansion capability, Congoleum opted for a 30,000 scfm system. The regenerative thermal oxidation unit consists of a central combustion chamber with five lobes extending radially outward. Each lobe is packed with ceramic refractory elements (saddles) which serve as heat exchange media. The elements are retained by perforated refractory blocks on the hot combustion chamber side and by a grating on the cold side. Estimated savings from the system, about a half million dollars the first year, are expected to significantly exceed Congoleum's original estimates. About half of the total savings will result from reduced consumption of natural gas since the unit is fueled mainly by the organic material in the process exhaust. The other half of the savings has resulted from improvements in production efficiency and the recycling of waste heat from the thermal oxidizer.« less

Applied Meteorology Unit (AMU)

NASA Technical Reports Server (NTRS)

Bauman, William H., Jr.; Crawford, Winifred; Short, David; Barrett, Joe; Watson, Leela

2008-01-01

This report summarizes the Applied Meteorology Unit (AMU) activities for the second quarter of Fiscal Year 2008 (January - March 2008). Projects described are: (1) Peak Wind Tool for User Launch Commit Criteria (LCC), (2) Peak Wind Tool for General Forecasting, (3) Situational Lightning Climatologies for Central Florida. Phase III, (4) Volume Averaged Height Integrated Radar Reflectivity (VAHIRR), (5) Impact of Local Sensors, (6) Radar Scan Strategies for the PAFB WSR-74C Replacement and (7) WRF Wind Sensitivity Study at Edwards Air Force Base.

The Effect of Personnel Stability on Organizational Performance: Do Battalions with Stable Command Groups Achieve Higher Training Proficiency at the National Training Center?

DTIC Science & Technology

2008-01-01

Graduate School and the students they work with on a routine basis. All three of my committee members have been superb mentors in helping me develop the...Deployable” and “Individual Replacement Induced Non-Deployable.” Wartime non-deployable status is provided to soldiers who are unavailable due to medical ...responder medical tasks, mastery of communication systems, and basic reporting requirements. The unit can progress to small-unit level collective training

Improving gas dehydrator efficiency; Glycol losses from dehydrator solved by mist eliminator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Franke, S.; Neal, R.; Patel, K.

1989-07-01

Triethylene glycol losses from a natural gas dehydrator unit were costing Winnie Pipeline Co. well over $100/day. Several possible causes had been investigated, and a second, smaller unit had been added because insufficient capacity was thought to cause glycol carryover from the contactor. Eventually, glycol losses were virtually eliminated by replacing the standard mist eliminator pad in the top of the contactor tower with a higher-efficiency type. Use of this type of pad is discussed in this paper.

KSC-2009-2521

NASA Image and Video Library

2009-04-02

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center in Florida, technicians help with the installation of the Science Instrument Command and Data Handling Unit, or SIC&DH, on the Multi-Use Lightweight Equipment Carrier. The SIC&DH will be installed on the Hubble Space Telescope during space shuttle Atlantis' STS-125 mission. This unit will replace the one that suffered a failure aboard the orbiting telescope on Sept. 27, 2008. Atlantis is targeted for launch on May 12. Photo credit: NASA/Dimitri Gerondidakis

KSC-2009-2520

NASA Image and Video Library

2009-04-02

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center in Florida, technicians help with the installation of the Science Instrument Command and Data Handling Unit, or SIC&DH, on the Multi-Use Lightweight Equipment Carrier. The SIC&DH will be installed on the Hubble Space Telescope during space shuttle Atlantis' STS-125 mission. This unit will replace the one that suffered a failure aboard the orbiting telescope on Sept. 27, 2008. Atlantis is targeted for launch on May 12. Photo credit: NASA/Dimitri Gerondidakis

KSC-2009-2522

NASA Image and Video Library

2009-04-02

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center in Florida, technicians look over the Science Instrument Command and Data Handling Unit, or SIC&DH, installed on the Multi-Use Lightweight Equipment Carrier. The SIC&DH will be installed on the Hubble Space Telescope during space shuttle Atlantis' STS-125 mission. This unit will replace the one that suffered a failure aboard the orbiting telescope on Sept. 27, 2008. Atlantis is targeted for launch on May 12. Photo credit: NASA/Dimitri Gerondidakis

KSC-2009-2523

NASA Image and Video Library

2009-04-02

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center in Florida, technicians check the Multi-Use Lightweight Equipment Carrier where the Science Instrument Command and Data Handling Unit, or SIC&DH, is being installed. The SIC&DH will be installed on the Hubble Space Telescope during space shuttle Atlantis' STS-125 mission. This unit will replace the one that suffered a failure aboard the orbiting telescope on Sept. 27, 2008. Atlantis is targeted for launch on May 12. Photo credit: NASA/Dimitri Gerondidakis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wu, Fu-Peng; Un, Hio-Ieng; Li, Yongxi

A new electron-deficient unit with fused 5-heterocyclic ring was developed by replacing a cyclopenta-1,3-diene from electron-rich donor indacenodithiophene (IDT) with cyclohepta- 4,6-diene-1,3-diimde unit. The imide bridging endows BBI with fixed planar configuration and both low the highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbit (LUMO) energy levels. Organic field-effect transistors (OFETs) based on BBI polymers exhibit electron mobility up to 0.34 cm2 V-1 s-1, which indicates that the BBI is a promising ntype semiconductor for optoelectronics.

The Impact of Political-Military Relations on the Use of German Military Power during Operation Barbarossa

DTIC Science & Technology

2007-06-15

Germany’s rearmament the Waffen -SS divisions began to receive priority in military equipment and personnel. Hitler placed more faith in the...Party’s army than the regular army. By War’s end in 1945 Himmler had control of over forty two Waffen -SS units, a significant number considering the...Army, efforts to micromanage the war, and event decision to replace army units with Waffen SS stemmed from this divergence. The problem worsened as

A new multiprogrammable isotopic powered cardiac pacemaker

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smyth, N.P.; Purdy, D.L.; Sager, D.

1982-09-01

A new multiprogrammable, isotopic-powered cardiac pacemaker was implanted in six patients as a custom device. Five were initial implants and one was a replacement. The patients were studied for up to two years. In five of the six cases it was found advantageous to change one of the programmable parameters. Multiprogrammability is obviously as important in an isotopic pulse generator as in a lithium unit, if not more so, because of the unit's greater longevity. Further studies are continuing in an FDA approved clinical trial.

The cost of cardiac surgery.

PubMed Central

Monro, J L; Mollo, S; Brookbanks, S; Conway, N; Ross, J K

1978-01-01

A study in Wessex has shown that at 1977 prices, and excluding the cost of equipment already installed in the unit, the cost of replacing a man's aortic valve in this unit is about 1800 pounds. Nevertheless, this seems a small price to pay for return to health and full working capacity, particularly since such patients no longer need to draw social security benefits and their tax contributions will return to normal, thus probably paying for the operation within two years. PMID:418846

Demonstration of Advanced Geophysics and Classification Methods on Munitions Response Sites: Closed Castner Range Fort Bliss, TX

DTIC Science & Technology

2016-04-01

Program ft foot/feet GPS Global Positioning System HE High Explosive ID Identification IDA Institute for Defense Analysis IMU Inertial Measurement Unit ISO...were replaced with two ski-shaped runners, and a new mount above the array was used to hold the Inertial Measurement Unit (IMU) and Trimble R8 Real...to collect a cued data measurement (Figure 9). The instrument’s pitch, roll , and yaw angles automatically were measured by the IMU. These angles and

The Extravehicular Maneuvering Unit's New Long Life Battery and Lithium Ion Battery Charger

NASA Technical Reports Server (NTRS)

Russell, Samuel P.; Elder, Mark A.; Williams, Anthony G.; Dembeck, Jacob

2010-01-01

The Long Life (Lithium Ion) Battery is designed to replace the current Extravehicular Mobility Unit Silver/Zinc Increased Capacity Battery, which is used to provide power to the Primary Life Support Subsystem during Extravehicular Activities. The Charger is designed to charge, discharge, and condition the battery either in a charger-strapped configuration or in a suit-mounted configuration. This paper will provide an overview of the capabilities and systems engineering development approach for both the battery and the charger

FASEA: A FPGA Acquisition System and Software Event Analysis for liquid scintillation counting

NASA Astrophysics Data System (ADS)

Steele, T.; Mo, L.; Bignell, L.; Smith, M.; Alexiev, D.

2009-10-01

The FASEA (FPGA based Acquisition and Software Event Analysis) system has been developed to replace the MAC3 for coincidence pulse processing. The system uses a National Instruments Virtex 5 FPGA card (PXI-7842R) for data acquisition and a purpose developed data analysis software for data analysis. Initial comparisons to the MAC3 unit are included based on measurements of 89Sr and 3H, confirming that the system is able to accurately emulate the behaviour of the MAC3 unit.

Biological Research in Canisters (BRIC) - Light Emitting Diode (LED)

NASA Technical Reports Server (NTRS)

Levine, Howard G.; Caron, Allison

2016-01-01

The Biological Research in Canisters - LED (BRIC-LED) is a biological research system that is being designed to complement the capabilities of the existing BRIC-Petri Dish Fixation Unit (PDFU) for the Space Life and Physical Sciences (SLPS) Program. A diverse range of organisms can be supported, including plant seedlings, callus cultures, Caenorhabditis elegans, microbes, and others. In the event of a launch scrub, the entire assembly can be replaced with an identical back-up unit containing freshly loaded specimens.

Aquarium Microbiome Response to Ninety-Percent System Water Change: Clues to Microbiome Management

PubMed Central

Van Bonn, William; LaPointe, Allen; Gibbons, Sean M.; Frazier, Angel; Hampton-Marcell, Jarrad; Gilbert, Jack

2016-01-01

The bacterial community composition and structure of water from an established teleost fish system was examined before, during and after a major water change to explore the impact of such a water-change disturbance on the stability of the aquarium water microbiome. The diversity and evenness of the bacterial community significantly increased following the 90% water replacement. While the change in bacterial community structure was significant, it was slight, and was also weakly correlated with changes in physicochemical parameters. Interestingly there was a significant shift in the correlative network relationships between operational taxonomic units from before to after the water replacement. We suggest this shift in network structure is due to the turnover of many taxa during the course of water replacement. These observations will inform future studies into manipulation of the microbiome by changing system environmental parameter values to optimize resident animal health. PMID:26031788

Evaluation of ultrasonic cavitation of metallic and non-metallic surfaces

NASA Technical Reports Server (NTRS)

Mehta, Narinder K.

1992-01-01

1,1,2 trichloro-1,2,2 trifluoro ethane (CFC-113) commercially known as Freon-113 is the primary test solvent used for validating the cleaned hardware at the Kennedy Space Center (KSC). Due to the ozone depletion problem, the current United States policy calls for the phase out of Freons by 1995. NASAs chlorofluorocarbon (CFC) replacement group at KSC has opted to use water as a replacement fluid for the validation process since water is non-toxic, inexpensive, and is environmentally friendly. The replacement validation method calls for the ultrasonification of the small parts with water at 52 C for a cycle or two of 10 min duration wash using commercial ultrasonic baths. In this project, experimental data was obtained to assess the applicability of the proposed validation method for any damage of the metallic and non-metallic surfaces resulting from ultrasonic cavitation.

Aquarium microbiome response to ninety-percent system water change: Clues to microbiome management.

PubMed

Van Bonn, William; LaPointe, Allen; Gibbons, Sean M; Frazier, Angel; Hampton-Marcell, Jarrad; Gilbert, Jack

2015-01-01

The bacterial community composition and structure of water from an established teleost fish system was examined before, during and after a major water change to explore the impact of such a water-change disturbance on the stability of the aquarium water microbiome. The diversity and evenness of the bacterial community significantly increased following the 90% water replacement. While the change in bacterial community structure was significant, it was slight, and was also weakly correlated with changes in physicochemical parameters. Interestingly there was a significant shift in the correlative network relationships between operational taxonomic units from before to after the water replacement. We suggest this shift in network structure is due to the turnover of many taxa during the course of water replacement. These observations will inform future studies into manipulation of the microbiome by changing system environmental parameter values to optimize resident animal health. © 2015 Wiley Periodicals, Inc.

KSC-02pd0671

NASA Image and Video Library

2002-05-15

KENNEDY SPACE CENTER, FLA. -- STS-111 Mission Specialist Philippe Perrin, with the French Space Agency, arrives at KSC aboard a T-38 jet aircraft to take part in Terminal Countdown Demonstration Test (TCDT) activities, along with the Expedition 5 crew, for launch of mission STS-111. Expedition 5 will travel on Space Shuttle Endeavour to the International Space Station as a replacement crew for Expedition 4. The TCDT is a rehearsal for launch and includes emergency egress training, familiarization with payload and a simulated launch countdown. Mission STS-111 is a utilization flight that will deliver equipment and supplies to the Station. Along with the Multi-Purpose Logisitics Module Leonardo, the payload includes the Mobile Base System, part of the Canadian Mobile Servicing System, or MSS, and an Orbital Replacement Unit, the replacement wrist/roll joint for the SSRMS (Canadarm2). Launch of Endeavour is scheduled for May 30, 2002

Advanced age and incidence of atrial fibrillation in the postoperative period of aortic valve replacement

PubMed Central

Pivatto Júnior, Fernando; Teixeira Filho, Guaracy Fernandes; Sant'anna, João Ricardo Michelin; Py, Pablo Mondim; Prates, Paulo Roberto; Nesralla, Ivo Abrahão; Kalil, Renato Abdala Karam

2014-01-01

Objective This study aims to describe the correlation between age and occurrence of atrial fibrillation after aortic stenosis surgery in the elderly as well as evaluate the influence of atrial fibrillation on the incidence of strokes, hospital length of stay, and hospital mortality. Methods Cross-sectional retrospective study of > 70 year-old patients who underwent isolated aortic valve replacement. Results 348 patients were included in the study (mean age 76.8±4.6 years). Overall, post-operative atrial fibrillation was 32.8% (n=114), but it was higher in patients aged 80 years and older (42.9% versus 28.8% in patients aged 70-79 years, P=0.017). There was borderline significance for linear correlation between age and atrial fibrillation (P=0.055). Intensive Care Unit and hospital lengths of stay were significantly increased in atrial fibrillation (P<0.001), but there was no increase in mortality or stroke associated with atrial fibrillation. Conclusion Post-operative atrial fibrillation incidence in aortic valve replacement is high and correlates with age in patients aged 70 years and older and significantly more pronounced in patients aged 80 years. There was increased length of stay at Intensive Care Unit and hospital, but there was no increase in mortality or stroke. These data are important for planning prophylaxis and early treatment for this subgroup. PMID:24896162

10 CFR 431.383 - Enforcement process for electric motors.

Code of Federal Regulations, 2014 CFR

2014-01-01

... general purpose electric motor of equivalent electrical design and enclosure rather than replacing the... equivalent electrical design and enclosure rather than machining and attaching an endshield. ... sample of up to 20 units will then be randomly selected from one or more subdivided groups within the...

Evaluation of alternative pozzolanic materials for partial replacement of Portland cement in concrete.

DOT National Transportation Integrated Search

2016-09-01

The supply of class F coal fly ash throughout the United States has recently diminished due to supply of natural gas and alternative energy sources as well as environmental restrictions. As a result, the concrete industry in the state of Florida has ...

An alternative transportation fuels update : a case study of the developing E85 industry.

DOT National Transportation Integrated Search

2011-10-01

As the United States imports more than half of its oil and overall consumption continues to climb, : the 1992 Energy Policy Act established the goal of having alternative fuels replace at least ten : percent of petroleum fuels used in the trans...

40 CFR 74.10 - Roles-EPA and permitting authority.

Code of Federal Regulations, 2010 CFR

2010-07-01

... allowance allocation, and allocating allowances for combustion or process sources that become affected units under this part; (2) Certifying or recertifying monitoring systems for combustion or process sources as... accounting for the replacement of thermal energy, closing accounts for opt-in sources that shut down, are...

40 CFR 63.863 - Compliance dates.

Code of Federal Regulations, 2010 CFR

2010-07-01

... startup date after March 13, 2001 must comply with the requirements in this subpart immediately upon startup of the affected source, except as specified in § 63.6(b). (c) The two existing semichemical..., therefore, must construct another type of chemical recovery unit to replace the two existing semichemical...

40 CFR 63.863 - Compliance dates.

Code of Federal Regulations, 2013 CFR

2013-07-01

... startup date after March 13, 2001 must comply with the requirements in this subpart immediately upon startup of the affected source, except as specified in § 63.6(b). (c) The two existing semichemical..., therefore, must construct another type of chemical recovery unit to replace the two existing semichemical...

40 CFR 63.863 - Compliance dates.

Code of Federal Regulations, 2012 CFR

2012-07-01

... startup date after March 13, 2001 must comply with the requirements in this subpart immediately upon startup of the affected source, except as specified in § 63.6(b). (c) The two existing semichemical..., therefore, must construct another type of chemical recovery unit to replace the two existing semichemical...

40 CFR 63.863 - Compliance dates.

Code of Federal Regulations, 2011 CFR

2011-07-01

... startup date after March 13, 2001 must comply with the requirements in this subpart immediately upon startup of the affected source, except as specified in § 63.6(b). (c) The two existing semichemical..., therefore, must construct another type of chemical recovery unit to replace the two existing semichemical...

40 CFR 63.863 - Compliance dates.

Code of Federal Regulations, 2014 CFR

2014-07-01

... startup date after March 13, 2001 must comply with the requirements in this subpart immediately upon startup of the affected source, except as specified in § 63.6(b). (c) The two existing semichemical..., therefore, must construct another type of chemical recovery unit to replace the two existing semichemical...

75 FR 42722 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-22

... Missile Cable Affairs Offices at missile bases reporting to Headquarters Air Global Strike Command... entry and replace with ``Director of Maintenance, Deputy Chief of Staff/Logistics, Headquarters United... Communications Branch, Headquarters Air Force Global Strike Command/A6ON, 414 Curtiss Road, Suite 227, Barksdale...

Hierarchical analysis of bridge decision makers : the role of new technology adoption in the timber bridge market : special project fiscal year 1992

DOT National Transportation Integrated Search

1995-08-01

Bridge design engineers and local highway officials make bridge replacement decisions across the : United States. The Analytical Hierarchy Process was used to characterize the bridge material selection : decision of these individuals. State Departmen...

Fly ash system technology improves opacity

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

2007-06-15

Unit 3 of the Dave Johnston Power Plant east of Glenrock, WY, USA had problems staying at or below the opacity limits set by the state. The unit makes use of a Lodge Cottrell precipitator. When the plant changed to burning Power River Basin coal, ash buildup became a significant issue as the fly ash control system was unable to properly evacuate hoppers on the unit. To overcome the problem, the PLC on the unit was replaced with a software optimization package called SmartAsh for the precipitator fly ash control system, at a cost of $500,000. After the upgrade, theremore » have been no plugged hoppers and the opacity has been reduced from around 20% to 3-5%. 2 figs.« less

Design parameters for toroidal and bobbin magnetics. [conversion from English to metric units

NASA Technical Reports Server (NTRS)

Mclyman, W. T.

1974-01-01

The adoption by NASA of the metric system for dimensioning to replace long-used English units imposes a requirement on the U.S. transformer designer to convert from the familiar units to the less familiar metric equivalents. Material is presented to assist in that transition in the field of transformer design and fabrication. The conversion data makes it possible for the designer to obtain a fast and close approximation of significant parameters such as size, weight, and temperature rise. Nomographs are included to provide a close approximation for breadboarding purposes. For greater convenience, derivations of some of the parameters are also presented.

Locomotor exercise in weightlessness

NASA Technical Reports Server (NTRS)

Thornton, W.; Whitmore, H.

1991-01-01

The requirements for exercise in space by means of locomotion are established and addressed with prototype treadmills for use during long-duration spaceflight. The adaptation of the human body to microgravity is described in terms of 1-G locomotor biomechanics, the effects of reduced activity, and effective activity-replacement techniques. The treadmill is introduced as a complement to other techniques of force replacement with reference given to the angle required for exercise. A motor-driven unit is proposed that can operate at a variety of controlled speeds and equivalent grades. The treadmills permit locomotor exercise as required for long-duration space travel to sustain locomotor and cardiorespiratory capacity at a level consistent with postflight needs.

MS Linnehan checks airlock hatch on middeck

NASA Image and Video Library

2002-03-05

STS109-E-5602 (5 March 2002) --- Astronaut Richard M. Linnehan, mission specialist, checks the airlock hatch as two crewmates on the other side, equipped with extravehicular mobility units (EMU) space suits, start their extravehicular activity (EVA). On the previous day astronauts Linnehan and John M. Grunsfeld replaced the starboard solar array on the Hubble Space Telescope (HST). This day's space walk went on to see astronauts James H. Newman and Michael J. Massimino replace the port solar array. Grunsfeld's suit, scheduled for two more space walks, is temporarily stowed on the mid deck floor at right. The image was recorded with a digital still camera.

Part II: managing perioperative hyperglycemia in total hip and knee replacement surgeries.

PubMed

Agos, Florence; Shoda, Casey; Bransford, Deborah

2014-09-01

Perioperative hyperglycemia management is an important factor in reducing the risk of surgical site infections (SSIs) in all patients regardless of existing history of diabetes. Reduction of SSIs is one of the quality indicators reported by the National Healthcare Safety Networks of the Centers for Disease Control and Prevention (CDC). In 2009 and 2010, the orthopedic surgical unit had an increased number of SSIs above the CDC benchmark. This article describes the impact of an evidence-based practice standard for perioperative hyperglycemia management in the reduction of SSIs in patients having total hip and knee replacement surgery. Copyright © 2014 Elsevier Inc. All rights reserved.

Control of estrus and ovulation in beef heifers.

PubMed

Patterson, David J; Thomas, Jordan M; Martin, Neal T; Nash, Justin M; Smith, Michael F

2013-11-01

Expanded use of artificial insemination (AI) and/or adoption of emerging reproductive technologies for beef heifers and cows require precise methods of estrous-cycle control. New protocols for inducing and synchronizing a fertile estrus in replacement beef heifers and postpartum beef cows in which progestins are used provide new opportunities for beef producers to synchronize estrus and ovulation and to facilitate fixed-time AI. This article reviews the various estrous synchronization protocols currently available for use in replacement beef heifers. New methods of inducing and synchronizing estrus now create the opportunity to significantly expand the use of AI in the United States cowherd. Copyright © 2013 Elsevier Inc. All rights reserved.

Renal replacement therapy in patients with severe precapillary pulmonary hypertension with acute right heart failure.

PubMed

Sztrymf, Benjamin; Prat, Dominique; Jacobs, Frédéric M; Brivet, François G; O'Callaghan, Dermot S; Price, Laura C; Jais, Xavier; Sitbon, Olivier; Simonneau, Gérald; Humbert, Marc

2013-01-01

Renal replacement therapy has been suggested as a therapeutic option in the setting of acute right ventricular failure in patients with severe precapillary pulmonary hypertension. However, there are few data supporting this strategy. To describe the clinical course and the prognosis of pulmonary hypertensive patients undergoing renal replacement therapy in the setting of acute right heart failure. This was a single-center retrospective study over an 11-year period. Data were collected from all patients with chronic precapillary pulmonary hypertension requiring catecholamine infusions for clinical worsening and acute kidney injury that necessitated renal replacement therapy. Fourteen patients were included. At admission, patients had a blood urea of 28.2 mmol/l (22.3-41.2), a creatinine level of 496 µmol/l (304-590), and a mean urine output in the 24 h preceding hospitalization of 200 ml (0-650). Sixty-eight renal replacement therapy sessions were performed, 36 of which were continuous and 32 of which were intermittent. Systemic hypotension occurred in 16/32 intermittent and 16/36 continuous sessions (p = 0.9). Two patients died during a continuous session. The intensive care unit-related, 1-, and 3-month mortality was 46.7, 66.7, and 73.3%, respectively. Renal replacement therapy is feasible in the setting of acute right ventricular failure in patients with severe precapillary pulmonary hypertension but is associated with a poor prognosis. The best modality and timing in this population remain to be defined. Copyright © 2012 S. Karger AG, Basel.

Phosphate-containing dialysis solution prevents hypophosphatemia during continuous renal replacement therapy

PubMed Central

BROMAN, M; CARLSSON, O; FRIBERG, H; WIESLANDER, A; GODALY, G

2011-01-01

Background Hypophosphatemia occurs in up to 80% of the patients during continuous renal replacement therapy (CRRT). Phosphate supplementation is time-consuming and the phosphate level might be dangerously low before normophosphatemia is re-established. This study evaluated the possibility to prevent hypophosphatemia during CRRT treatment by using a new commercially available phosphate-containing dialysis fluid. Methods Forty-two heterogeneous intensive care unit patients, admitted between January 2007 and July 2008, undergoing hemodiafiltration, were treated with a new Gambro dialysis solution with 1.2 mM phosphate (Phoxilium) or with standard medical treatment (Hemosol B0). The patients were divided into three groups: group 1 (n=14) receiving standard medical treatment and intravenous phosphate supplementation as required, group 2 (n=14) receiving the phosphate solution as dialysate solution and Hemosol B0 as replacement solution and group 3 (n=14) receiving the phosphate-containing solution as both dialysate and replacement solutions. Results Standard medical treatment resulted in hypophosphatemia in 11 of 14 of the patients (group 1) compared with five of 14 in the patients receiving phosphate solution as the dialysate solution and Hemosol B0 as the replacement solution (group 2). Patients treated with the phosphate-containing dialysis solution (group 3) experienced stable serum phosphate levels throughout the study. Potassium, ionized calcium, magnesium, pH, pCO2 and bicarbonate remained unchanged throughout the study. Conclusion The new phosphate-containing replacement and dialysis solution reduces the variability of serum phosphate levels during CRRT and eliminates the incidence of hypophosphatemia. PMID:21039362

User-perceived reliability of unrepairable shared protection systems with functionally identical units

NASA Astrophysics Data System (ADS)

Ozaki, Hirokazu; Kara, Atsushi; Cheng, Zixue

2012-05-01

In this article, we investigate the reliability of M-for-N (M:N) shared protection systems. We focus on the reliability that is perceived by an end user of one of N units. We assume that any failed unit is instantly replaced by one of the M units (if available). We describe the effectiveness of such a protection system in a quantitative manner under the condition that the failed units are not repairable. Mathematical analysis gives the closed-form solution of the reliability and mean time to failure (MTTF). We also analyse several numerical examples of the reliability and MTTF. This result can be applied, for example, to the analysis and design of an integrated circuit consisting of redundant backup components. In such a device, repairing a failed component is unrealistic. The analysis provides useful information for the design for general shared protection systems in which the failed units are not repaired.

Mitochondrial Replacement Techniques, Scientific Tourism, and the Global Politics of Science.

PubMed

Chan, Sarah; Palacios-González, César; De Jesús Medina Arellano, María

2017-09-01

The United Kingdom is the first and so far only country to pass explicit legislation allowing for the licensed use of the new reproductive technology known as mitochondrial replacement therapy. The techniques used in this technology may prevent the transmission of mitochondrial DNA diseases, but they are controversial because they involve the manipulation of oocytes or embryos and the transfer of genetic material. Some commentators have even suggested that MRT constitutes germline genome modification. All eyes were on the United Kingdom as the most likely location for the first MRT birth, so it was a shock when, on September 27, 2016, an announcement went out that the first baby to result from use of the intervention had already been born. In New York City, United States-based scientist John Zhang used maternal spindle transfer (one of the recognized MRT methods) to generate five embryos for a woman carrying oocytes with deleterious mutations of the mitochondrial DNA. Zhang then shipped the only euploid embryo to Mexico, where it was transferred to the mother's uterus. Zhang's team's travel across international borders to carry out experimental procedures represents a form of scientific tourism that has not been properly ethically explored; it can, however, have seriously detrimental effects for developing countries. © 2017 The Hastings Center.

Magnetostrictive patch sensor system for battery-less real-time measurement of torsional vibrations of rotating shafts

NASA Astrophysics Data System (ADS)

Lee, Jun Kyu; Seung, Hong Min; Park, Chung Il; Lee, Joo Kyung; Lim, Do Hyeong; Kim, Yoon Young

2018-02-01

Real-time uninterrupted measurement for torsional vibrations of rotating shafts is crucial for permanent health monitoring. So far, strain gauge systems with telemetry units have been used for real-time monitoring. However, they have a critical disadvantage in that shaft operations must be stopped intermittently to replace telemetry unit batteries. To find an alternative method to carry out battery-less real-time measurement for torsional vibrations of rotating shafts, a magnetostrictive patch sensor system was proposed in the present study. Since the proposed sensor does not use any powered telemetry system, no battery is needed and thus there is no need to stop rotating shafts for battery replacement. The proposed sensor consists of magnetostrictive patches and small magnets tightly bonded onto a shaft. A solenoid coil is placed around the shaft to convert magnetostrictive patch deformation by shaft torsional vibration into electric voltage output. For sensor design and characterization, investigations were performed in a laboratory on relatively small-sized stationary solid shaft. A magnetostrictive patch sensor system was then designed and installed on a large rotating propulsion shaft of an LPG carrier ship in operation. Vibration signals were measured using the proposed sensor system and compared to those measured with a telemetry unit-equipped strain gauge system.

Safety Management of a Clinical Process Using Failure Mode and Effect Analysis: Continuous Renal Replacement Therapies in Intensive Care Unit Patients.

PubMed

Sanchez-Izquierdo-Riera, Jose Angel; Molano-Alvarez, Esteban; Saez-de la Fuente, Ignacio; Maynar-Moliner, Javier; Marín-Mateos, Helena; Chacón-Alves, Silvia

2016-01-01

The failure mode and effect analysis (FMEA) may improve the safety of the continuous renal replacement therapies (CRRT) in the intensive care unit. We use this tool in three phases: 1) Retrospective observational study. 2) A process FMEA, with implementation of the improvement measures identified. 3) Cohort study after FMEA. We included 54 patients in the pre-FMEA group and 72 patients in the post-FMEA group. Comparing the risks frequencies per patient in both groups, we got less cases of under 24 hours of filter survival time in the post-FMEA group (31 patients 57.4% vs. 21 patients 29.6%; p < 0.05); less patients suffered circuit coagulation with inability to return the blood to the patient (25 patients [46.3%] vs. 16 patients [22.2%]; p < 0.05); 54 patients (100%) versus 5 (6.94%) did not get phosphorus levels monitoring (p < 0.05); in 14 patients (25.9%) versus 0 (0%), the CRRT prescription did not appear on medical orders. As a measure of improvement, we adopt a dynamic dosage management. After the process FMEA, there were several improvements in the management of intensive care unit patients receiving CRRT, and we consider it a useful tool for improving the safety of critically ill patients.

Replacement of the International Standard for Tetanus Antitoxin and the Use of the Standard in the Flocculation Test

PubMed Central

Spaun, J.; Lyng, J.

1970-01-01

Since 1935 the International Unit for Tetanus Antitoxin has been defined as the activity contained in a certain weight of the first International Standard for Tetanus Antitoxin. As stocks of this standard had become depleted, 11 laboratories in 8 countries were requested to participate in a collaborative assay of a preparation proposed as a replacement. The assay results were analysed and presented to the WHO Expert Committee on Biological Standardization in 1969 which established the preparation studied as the second International Standard for Tetanus Antitoxin and defined the International Unit for Tetanus Antitoxin as the activity contained in 0.03384 mg of the second International Standard for Tetanus Antitoxin. This definition would ensure the continuity of the size of this international unit. The analysis of the collaborative studies also showed that the second International Standard for Tetanus Antitoxin has suitable properties for use in the flocculation test for the determination of the antigen content of tetanus toxoids in Lf values. The designation Lf-equivalent is described and the problems relating to the use of this term for the expression of results of in vitro assays are analysed in relation to the use of international units for expressing results of in vivo assays. As the second International Standard for Tetanus Antitoxin has an in vivo/in vitro ratio of 1.4, the Lf-equivalent of this antitoxin is 1.4 times less than its unitage. PMID:5310949

Effect of π-bridge units on properties of A-π-D-π-A-type nonfullerene acceptors for organic solar cells.

PubMed

Wang, Yan-Ling; Li, Quan-Song; Li, Ze-Sheng

2018-05-15

Acceptor-π-donor-π-acceptor (A-π-D-π-A)-types of small molecules are very promising nonfullerene acceptors to overcome the drawbacks of fullerene derivatives such as the weak absorption ability and electronic adjustability. However, only few attempts have been made to develop π-bridge units to construct highly efficient acceptors in OSCs. Herein, taking the reported acceptor P1 as a reference, five small-structured acceptors (P2, P3, P4, P5, and P6) have been designed via the replacement of the π-bridge unit. A combination of quantum chemistry and Marcus theory approaches is employed to investigate the effect of different π-bridge units on the optical, electronic, and charge transport properties of P1-P6. The calculation results show that the designed molecules P2 and P5 can become potential acceptor replacements of P1 due to their red-shifted absorption bands, appropriate energy levels, low exciton binding energy, and high electron affinity and electron mobility. Additionally, compared with P3HT/P1, P3HT/P2 and P3HT/P5 exhibit stronger and wider absorption peaks, larger electron transfer distances (DCT), greater transferred charge amounts (Δq), and smaller overlaps (Λ), which shows that P2 and P5 have more significant electron transfer characteristics and favorable exciton dissociation capabilities for enhancing the short-circuit current density (JSC) and thus, they are potential acceptors in OSCs.

Functionalization-Free Microfluidic Electronic Tongue Based on a Single Response.

PubMed

Shimizu, Flavio M; Todão, Fagner R; Gobbi, Angelo L; Oliveira, Osvaldo N; Garcia, Carlos D; Lima, Renato S

2017-07-28

Electronic tongues (e-tongues) are promising analytical devices for a variety of applications to address the challenges of quality control in water monitoring and industries of foods, beverages, and pharmaceuticals. A crucial drawback in the current e-tongues is the need to recalibrate the device when one or more sensing units (usually with modified surface) are replaced. Another downside is the necessity to perform subsequent surface modifications and analyses to each of the diverse sensing units, undermining the simplicity and velocity of the method. These features have prevented widespread commercial use of the e-tongues. In this paper, we introduce a microfluidic e-tongue that overcomes all such limitations. The key principle of global selectivity of the e-tongue was achieved by recording only a single response, namely, the equivalent admittance spectrum of an association of resistors in parallel. Such resistors consisted of five nonfunctionalized stainless steel microwires (sensing units), which were short-circuited and coated with gold, platinum, nickel, iron, and aluminum oxide films. The microwires were inserted in a chip composed of a single piece of polydimethylsiloxane (PDMS). Using impedance spectroscopy, the e-tongue was successfully applied in classification of basic tastes at a concentration below the threshold for the human tongue. In addition, our chip allowed the distinction of various chemicals used in oil industry. Finally, our cleanroom-free prototyping allows the mass production of chips with easily replaceable and reproducible sensing units. Hence, one can now envisage the widespread dissemination of e-tongues with fast and reproducible data.

Renewable Energy for the Next Generation

ERIC Educational Resources Information Center

Barton, Leslie

2005-01-01

Renewable energy is harnessed from natural and sustainable sources, like wind, sun and water. They offer a pollution-free, endless source of electricity that is crucial in the fight against climate change. Every unit of this "green" electricity directly replaces electricity normally generated from conventional polluting sources such as coal or…

Robots Are Taking Over--Who Does What.

ERIC Educational Resources Information Center

Garrison, H. Don

Robots are machines designed to replace human labor. A fear of vast unemployment due to robots seems unfounded, however, since industrialization creates many more jobs and automation requires technologists to build, program, maintain, and operate sophisticated equipment. Robots possess an intelligence unit, a manipulator, and an end effector.…

US EVA 15 EMU Prep

NASA Image and Video Library

2010-08-07

ISS024-E-011561 (7 Aug. 2010) --- NASA astronaut Tracy Caldwell Dyson, Expedition 24 flight engineer, dons her Extravehicular Mobility Unit (EMU) spacesuit in the Quest airlock of the International Space Station in preparation for the first of three planned spacewalks to remove and replace an ammonia pump module that failed July 31.

Estimating the Cost of Standardized Student Testing in the United States.

ERIC Educational Resources Information Center

Phelps, Richard P.

2000-01-01

Describes and contrasts different methods of estimating costs of standardized testing. Using a cost-accounting approach, compares gross and marginal costs and considers testing objects (test materials and services, personnel and student time, and administrative/building overhead). Social marginal costs of replacing existing tests with a national…

40 CFR 265.221 - Design and operating requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... effective date of a prohibition pursuant to § 268.5 of this chapter, within this 48-month period. [50 FR... (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND... each replacement of an existing surface impoundment unit must install two or more liners, and a...

40 CFR 265.221 - Design and operating requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... effective date of a prohibition pursuant to § 268.5 of this chapter, within this 48-month period. [50 FR... (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND... each replacement of an existing surface impoundment unit must install two or more liners, and a...

40 CFR 265.221 - Design and operating requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... effective date of a prohibition pursuant to § 268.5 of this chapter, within this 48-month period. [50 FR... (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND... each replacement of an existing surface impoundment unit must install two or more liners, and a...

40 CFR 265.221 - Design and operating requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... effective date of a prohibition pursuant to § 268.5 of this chapter, within this 48-month period. [50 FR... (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND... each replacement of an existing surface impoundment unit must install two or more liners, and a...

40 CFR 265.221 - Design and operating requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... effective date of a prohibition pursuant to § 268.5 of this chapter, within this 48-month period. [50 FR... (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND... each replacement of an existing surface impoundment unit must install two or more liners, and a...

77 FR 44562 - Housing Assistance Due to Structural Damage

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-30

...: Temporary Housing: Money is available to rent a different place to live for a limited period of time. When... housing unit. Housing Repair: Money is available to homeowners to repair disaster damage to their primary... make the damaged home safe, sanitary, and functional. Housing Replacement: Money is available to...

40 CFR 265.254 - Design and operating requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... DISPOSAL FACILITIES Waste Piles § 265.254 Design and operating requirements. The owner or operator of each new waste pile on which construction commences after January 29, 1992, each lateral expansion of a waste pile unit on which construction commences after July 29, 1992, and each such replacement of an...

Hubble Space Telescope (HST) at Lockheed Facility during preflight assembly

NASA Image and Video Library

1988-03-31

A mechanical arm positions the axial scientific instrument (SI) module (orbital replacement unit (ORU)) just outside the open doors of the Hubble Space Telescope (HST) Support System Module (SSM) as clean-suited technicians oversee the process. HST assembly is being completed at the Lockheed Facility in Sunnyvale, California.

78 FR 8999 - Airworthiness Directives; The Boeing Company Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-07

...-400 series airplanes. This proposed AD was prompted by reports of auxiliary power unit (APU) faults... the APU power feeder cables; replacing the clamps and installing grommets; and related investigative and corrective actions if necessary. We are proposing this AD to detect and correct chafing of the APU...

77 FR 33202 - Department of the Air Force

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-05

... DEPARTMENT OF DEFENSE Department of the Air Force Corrected Intent To Grant a Partially Exclusive Patent License AGENCY: The United States Air Force, DoD. SUMMARY: This notice replaces the one published... implements Public Law 96- 517, as amended; the Department of the Air Force announces its intention to grant...

Real Electronic Commerce: Smart Cards on the Superhighway.

ERIC Educational Resources Information Center

Birch, David

1997-01-01

Technologies of payment rather than technologies of connection are the real trigger for the expansion of electronic commerce on the Internet. This article discusses "smart cards," highlighting Mondex, the electronic purse developed in the United Kingdom. Predicts that cash will be replaced by "e-cash," which is cheaper to make,…

Towards Improved Optical Limiters

DTIC Science & Technology

2002-05-03

nitrophthalonitrile, 3.37 g of potassium carbonate, and 0.54 g of neopentyl glycol were added to 10 mL of dry DMSO in a round bottom flask. The... glycol oxygens which in turn replace the nitro groups of the phthalonitrile and form a bond. This substitution reaction produces the bridge unit as

78 FR 15934 - North Pacific Fishery Management Council; Public Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-13

... (USCG) Report United States Fish & Wildlife Service (USFWS) Report Protected Species Report 2. Observer... replacement Gulf of Alaska (GOA) sideboards. 4. Steller Sea Lions (SSL) Environmental Impact Statement (EIS... following issues: 1. Round Island Analysis. 2. Steller Sea Lions. 3. Scallop SAFE. 4. CQE block limits. 5...

Spare EXT MDM Preparation

NASA Image and Video Library

2014-04-18

ISS039-E-013244 (18 April 2014) --- NASA astronaut Rick Mastracchio, Expeditionn 39 flight engineer, replaces the Enhanced Input/Output Control Unit Circuit Card of the spare External Multiplexer/Demultiplexer (MDM), in preparation for an upcoming spacewalk. He will be joined by fellow NASA astronaut and Flight Engineer Steve Swanson on the spacewalk.

A Distance Learning Case Study.

ERIC Educational Resources Information Center

Boord, Patricia M.

1998-01-01

To address diminishing resources and increased training demands, the Operational Training Unit (OTU) of the Federal Bureau of Investigation has saved almost $2 million by developing a distance education course to replace one full week of training at the FBI Academy. Discussion focuses on major issues faced by OTU in designing/delivering this…

Our Way of Life May Be Killing Us.

ERIC Educational Resources Information Center

USA Today, 1979

1979-01-01

Temple University psychologist Barry Harris notes that today the major causes of death and chronic illness in the United States are stress-related. He asserts that traditional medical care, focused on disease, is inadequate and should be replaced by a strategy emphasizing healthy living and stress management. (Author/SJL)

Effect of conifer encroachment into aspen stands on understory biomass

Treesearch

B. R. Stam; J. C. Malechek; D. L. Bartos; J. E. Browns; E. B. Godfrey

2008-01-01

Conifers (Picea and Abies spp.) have replaced aspen (Populus tremuloides Michx.) over much of aspen's historic range in the western United States. We measured the impact of this change upon the production of understory vegetation potentially useful as forage for livestock and wildlife on two southern Utah...

Moral Education in Some English-Speaking Societies: Antinomian and Fundamentalist Challenges.

ERIC Educational Resources Information Center

Partington, Geoffrey

1990-01-01

Finds Protestant fundamentalists and Muslims in England, Australia, and the United States turning away from government schools, finding official policies antithetical to their beliefs. Argues that traditional Judaeo-Christian beliefs have been replaced by the antinomianism of those opposed to any universal moral law. Suggests that the present…

RISK ASSESSMENT AND MANAGEMENT OF WATER SUPPLY SYSTEM - INFRASTRUCTURE INITIATIVE FOR THE 21ST CENTURY

EPA Science Inventory

The current problem in the United States is that the water infrastructure is aging and spending has not been adequate to repair, replace, or rehabilitate drinking water distribution systems and wastewater collection systems. The American Society of Civil Engineers Report Card in...

Dry-extrusion of Asian Carp to supplement natural methionine for organic poultry production

USDA-ARS?s Scientific Manuscript database

Methionine, a sulfur containing amino acid, is essential for healthy poultry production. Synthetic methionine is commonly used as a supplement in conventional poultry. However, for organic poultry in the United States, a natural, cost effective source of methionine that can replace synthetic methion...

Feeding & Management of Dairy Calves & Heifers. Teacher's Guide.

ERIC Educational Resources Information Center

Bjoraker, Walt

This guide is designed to assist postsecondary and secondary teachers of agriculture in their use of the University of Wisconsin bulletin "Raising Dairy Replacements" in their dairy science instructional program. Eight lessons are provided in this unit: breeding decisions, management of cows from breeding to calving, care at calving time, the…

Growing Scientists: A Partnership between a University and a School District

ERIC Educational Resources Information Center

Woods, Teresa Marie

2012-01-01

Precollege science education in the United States has virtually always been influenced by university scientists to one degree or another. Partnership models for university scientist--school district collaborations are being advocated to replace outreach models. Although the challenges for such partnerships are well documented, the means of…

Maximizing Autonomy: Reforming Personal Support Laws in Sweden and the United States.

ERIC Educational Resources Information Center

Herr, Stanley S.

1995-01-01

Forms of guardianship for U.S. individuals with disabilities are reviewed, and Swedish legal and public policy innovations that replace guardianship with personal support services, such as mentors and personal assistants, are considered. The impact of Sweden's reforms on autonomy, independence, and integration is addressed. (Author/SW)

78 FR 76402 - Notice of Proposed Buy America Waiver for the Pad and Rubber Boot of a Concrete Block for a Low...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-17

... replacement parts manufactured in the United States; and (3) MTA's market research demonstrating the extent to... it likely would have to find a U.S.-manufactured pad and rubber boot, MTA began conducting market research [[Page 76403

Empirical Analysis of the Influence of Forest Extent on Annual and Seasonal Surface Temperatures for the Continental United States

EPA Science Inventory

Most scenario‐based climate modeling studies indicate that replacing temperate forest with cropland will promote cooling by reducing surface air temperatures. These results are inconsistent with fieldbased microclimate studies that have found that forests are cooler, wetter, and...

Beginning a Learning Community: Pilot Fall 2006

ERIC Educational Resources Information Center

Buttram, Shirley

2016-01-01

Colleges and universities across the United States are still enrolling students who are underprepared for college-level courses of study. Tinto (1998) stated at the Conference on Replacing Remediation in Higher Education: "Students are entering college with no more than a sixth-grade education in basic skills such as reading, writing, and…

78 FR 18479 - Drawbridge Operation Regulations; Pass Manchac, LA

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-27

... governing the operation of the Canadian National (CN) Railroad automated bascule span drawbridge across Pass... necessary to upgrade the electrical drive system and replace the seals on the gear drive unit that operates... Operations, telephone 202-366-9826. SUPPLEMENTARY INFORMATION: The CN Railroad has requested a temporary...

Decentralized University Budgeting, United with a More Flexible Tuition Structure

ERIC Educational Resources Information Center

Fethke, Gary

2014-01-01

With tuition revenues replacing state appropriations as the primary source of public university funding, it becomes difficult for universities to use historically based budget allocations and inflexible tuition structures to subsidize high-cost programs. It is argued here that combining targeted subsidies with a flexible tuition structure and…

75 FR 4416 - Policy on Cooperating Associations, Draft Director's Order #32

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-27

...) agreement. This policy will apply to all units of the national park system, and will replace the previous... reflect the findings and recommendations of the Cooperating Association Steering Committee submitted to the National Leadership Council in August 2009. These recommendations include as follows: The primary...

77 FR 36209 - Airworthiness Directives; Airbus Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-18

... number of the installed RAT actuator, and re-identification of the actuator and RAT, or replacement of the RAT actuator with a serviceable unit and re-identification of the RAT, if necessary. We are... number, and serial number of the installed RAT actuator, and re- identification of the actuator and RAT...

Media and the Rise of Celebrity Culture.

ERIC Educational Resources Information Center

Henderson, Amy

1992-01-01

Addresses the media's role in changing the nature of heroes in the United States. Describes the changes in cultural values that resulted in statesmen and soldiers being replaced by athletes and film and television celebrities. Attributes change to the development of the consumer society, centralization of the entertainment industry, and advances…

Babies Bottom Out--A 'Maybe Boom'

ERIC Educational Resources Information Center

Science News, 1977

1977-01-01

Data for the period September 1976 through April 1977 indicate a rise in the United States birth rate; however, the rate is still below the replacement level. It is speculated that the increase is an "echo" effect to the post-World War II baby boom which peaked in 1957. (SL)

The OSCE Has Landed: One Small Step for British Psychiatry?

ERIC Educational Resources Information Center

Sauer, Justin; Hodges, Brian; Santhouse, Alastair; Blackwood, Nigel

2005-01-01

Objective: In the United Kingdom (UK), an objective structured clinical examination (OSCE) has replaced the individual patient assessment (IPA) for part 1 of the membership examination of the Royal College of Psychiatrists (MRCPsych). The authors' assessment of the OSCE was conducted. Method: Residents completed and evaluated an OSCE designed…

25 CFR 700.183 - Determination of replacement housing benefit.

Code of Federal Regulations, 2010 CFR

2010-04-01

...; (1) The amount of the fair market value of the habitation and improvements purchased from an eligible... dwelling is less than the fair market value of the habitation and improvements purchased from an eligible... Four Family Dwelling Units). (2) The most recent Boecht Building Cost Modifier. (3) The experience of...

7 CFR 28.956 - Prescribed fees.

Code of Federal Regulations, 2014 CFR

2014-01-01

.... sample 42.00 3.0Furnishing standard color tiles for calibrating cotton colormeters, per set of five tiles... outside continental United States 165.00 3.1Furnishing single color calibration tiles for use with specific instruments or as replacements in above sets, each tile: a. f.o.b. Memphis, Tennessee 22.00 b...

7 CFR 28.956 - Prescribed fees.

Code of Federal Regulations, 2012 CFR

2012-01-01

.... sample 42.00 3.0Furnishing standard color tiles for calibrating cotton colormeters, per set of five tiles... outside continental United States 165.00 3.1Furnishing single color calibration tiles for use with specific instruments or as replacements in above sets, each tile: a. f.o.b. Memphis, Tennessee 22.00 b...

A National Strategy for Lifelong Learning.

ERIC Educational Resources Information Center

Coffield, Frank, Ed.

The first paper of this set of 12 conference papers, "Nine Learning Fallacies and Their Replacement by a National Strategy for Lifelong Learning," by Frank Coffield, synthesizes the opinions of other participants, and goes beyond them to set forth an outline of a strategy for lifelong learning in the United Kingdom. Following this…

Protein and calorie prescription for children and young adults receiving continuous renal replacement therapy: a report from the Prospective Pediatric Continuous Renal Replacement Therapy Registry Group.

PubMed

Zappitelli, Michael; Goldstein, Stuart L; Symons, Jordan M; Somers, Michael J G; Baum, Michelle A; Brophy, Patrick D; Blowey, Douglas; Fortenberry, James D; Chua, Annabelle N; Flores, Francisco X; Benfield, Mark R; Alexander, Steven R; Askenazi, David; Hackbarth, Richard; Bunchman, Timothy E

2008-12-01

Few published reports describe nutrition provision for critically ill children and young adults with acute kidney injury receiving continuous renal replacement therapy. The goals of this study were to describe feeding practices in pediatric continuous renal replacement therapy and to evaluate factors associated with over- and under-prescription of protein and calories. Retrospective database study. Multicenter study in pediatric critical care units. Patients with acute kidney injury (estimated glomerular filtration rate < 75 mL/min/1.73 m at continuous renal replacement therapy initiation) enrolled in the Prospective Pediatric Continuous Renal Replacement Therapy Registry. None. Nutrition variables: initial and maximal protein (g/kg/day) and caloric (kcal/kg/day) prescription and predicted resting energy expenditure (kcal/kg/day). We determined factors predicting initial and maximal protein and caloric prescription by multivariate analysis. One hundred ninety-five patients (median [interquartile range] age = 8.1 [12.8] yrs, 56.9% men) were studied. Mean protein and caloric prescriptions at continuous renal replacement therapy initiation were 1.3 +/- 1.5 g/kg/day (median, 1.0; range, 0-10) and 37 +/- 27 kcal/kg/day (median, 32; range, 0-107). Mean maximal protein and caloric prescriptions during continuous renal replacement therapy were 2.0 +/- 1.5 g/kg/day (median, 1.7; range, 0-12) and 48 +/- 32 kcal/kg/day (median, 43; range, 0-117). Thirty-four percent of patients were initially prescribed < 1 g/kg/day protein; 23% never attained > 1 g/kg/day protein prescription. By continuous renal replacement therapy day 5, median protein prescribed was > 2 g/kg/day. Protein prescription practices differed substantially between medical centers with 5 of 10 centers achieving maximal protein prescription of > 2 g/kg/day in > or = 40% of patients. Caloric prescription exceeded predicted resting energy expenditure by 30%-100%. Factors independently associated with maximal protein and caloric prescription while on continuous renal replacement therapy were younger age, initial protein and caloric prescription and number of continuous renal replacement therapy treatment days (p < 0.05). Protein prescription in pediatric continuous renal replacement therapy may be inadequate. Inter-center variation exists with respect to nutrition prescription. Feeding practice standardization and research in pediatric acute kidney injury nutrition are essential to begin providing evidence-based feeding recommendations.

Total or Partial Knee Arthroplasty Trial - TOPKAT: study protocol for a randomised controlled trial

PubMed Central

2013-01-01

Background In the majority of patients with osteoarthritis of the knee the disease originates in the medial compartment. There are two fundamentally different approaches to knee replacement for patients with unicompartmental disease: some surgeons feel that it is always best to replace both the knee compartments with a total knee replacement (TKR); whereas others feel it is best to replace just the damaged component of the knee using a partial or unicompartment replacement (UKR). Both interventions are established and well-documented procedures. Little evidence exists to prove the clinical and cost-effectiveness of either management option. This provides an explanation for the high variation in treatment of choice by individual surgeons for the same knee pathology. The aim of the TOPKAT study will be to assess the clinical and cost effectiveness of TKRs compared to UKRs in patients with medial compartment osteoarthritis. Methods/Design The design of the study is a single layer multicentre superiority type randomised controlled trial of unilateral knee replacement patients. Blinding will not be possible as the surgical scars for each procedure differ. We aim to recruit 500 patients from approximately 28 secondary care orthopaedic units from across the UK including district general and teaching hospitals. Participants will be randomised to either UKR or TKR. Randomisation will occur using a web-based randomisation system. The study is pragmatic in terms of implant selection for the knee replacement operation. Participants will be followed up for 5 years. The primary outcome is the Oxford Knee Score, which will be collected via questionnaires at 2 months, 1 year and then annually to 5 years. Secondary outcomes will include cost-effectiveness, patient satisfaction and complications data. Trial registration Current Controlled Trials ISRCTN03013488; ClinicalTrials.gov Identifier: NCT01352247 PMID:24028414

Pharmacokinetics and Pharmacodynamics of Piperacillin-Tazobactam in 42 Patients Treated with Concomitant CRRT

PubMed Central

Bauer, Seth R.; Salem, Charbel; Connor, Michael J.; Groszek, Joseph; Taylor, Maria E.; Wei, Peilin; Tolwani, Ashita J.

2012-01-01

Summary Background and objectives Current recommendations for piperacillin-tazobactam dosing in patients receiving continuous renal replacement therapy originate from studies with relatively few patients and lower continuous renal replacement therapy doses than commonly used today. This study measured the pharmacokinetic and pharmacodynamic characteristics of piperacillin-tazobactam in patients treated with continuous renal replacement therapy using contemporary equipment and prescriptions. Design, setting, participants, & measurements A multicenter prospective observational study in the intensive care units of two academic medical centers was performed, enrolling patients with AKI or ESRD receiving piperacillin-tazobactam while being treated with continuous renal replacement therapy. Pregnant women, children, and patients with end stage liver disease were excluded from enrollment. Plasma and continuous renal replacement therapy effluent samples were analyzed for piperacillin and tazobactam levels using HPLC. Pharmacokinetic and pharmacodynamic parameters were calculated using standard equations. Multivariate analyses were used to examine the association of patient and continuous renal replacement therapy characteristics with piperacillin pharmacokinetic parameters. Results Forty-two of fifty-five subjects enrolled had complete sampling. Volume of distribution (median=0.38 L/kg, intraquartile range=0.20 L/kg) and elimination rate constants (median=0.104 h−1, intraquartile range=0.052 h−1) were highly variable, and clinical parameters could explain only a small fraction of the large variability in pharmacokinetic parameters. Probability of target attainment for piperacillin was 83% for total drug but only 77% when the unbound fraction was considered. Conclusions There is significant patient to patient variability in pharmacokinetic/pharmacodynamic parameters in patients receiving continuous renal replacement therapy. Many patients did not achieve pharmacodynamic targets, suggesting that therapeutic drug monitoring might optimize therapy. PMID:22282479

Evaluation of a bisphosphonate enriched ultra-high molecular weight polyethylene for enhanced total joint replacement bearing surface functionality

NASA Astrophysics Data System (ADS)

Wright-Walker, Cassandra Jane

Each year in the United States there is an increasing trend of patients receiving total joint replacement (TJR) procedures. Approximately a half million total knee replacements (TKRs) are performed annually in the United States with increasing prevalence attributed to baby-boomers, obesity, older, and younger patients. This trend is also seen for total hip replacements (THRs) as well. The use of ultra high molecular weight polyethylene (UHMWPE) inserts in TJRs results in wear particle-induced osteolysis, which is the predominant cause for prosthesis failure and revision surgery. Sub-micron size particle generation is inevitable despite the numerous efforts in improving this bearing material. Work by others has shown that the use of oral and intravenous systemic bisphosphonates (BP) can significantly minimize periprosthetic osteolysis. However, the systemic delivery and the high solubility of BPs results in a predominant portion of the drug being excreted via the kidney without reaching its target, bone. This doctoral research project is focused on the development and evaluation of a novel method to administer BPs locally using the inherent wear of UHMWPE for possible use as an anti-osteolysis treatment. For new materials to be considered, they must be mechanically and tribologically comparable to the current gold standard, UHMWPE. In order to evaluate this material, mechanical, drug elution and tribological experiments were performed to allow assessment of material properties. Tensile tests showed comparable yield stress and pin-on-disk testing showed comparable wear to standard virgin UHMWPE. Further, drug elution tests have shown that BP was released from the enriched material both in static and dynamic conditions. Additionally, an aggressive 2 million cycle total knee simulator experiment has shown statistically similar wear results for the two materials. Overall, this research has provided the groundwork for further characterization and development of a new potential material for total joint replacements as an enhancement to standard UHMWPE. This material shows significant potential as an alternative bearing material to indirectly increase TJR longevity by addressing osteolysis related issues.

Effect of prophylactic non-invasive mechanical ventilation on functional capacity after heart valve replacement: a clinical trial

PubMed Central

de Araújo-Filho, Amaro Afrânio; de Cerqueira-Neto, Manoel Luiz; de Assis Pereira Cacau, Lucas; Oliveira, Géssica Uruga; Cerqueira, Telma Cristina Fontes; de Santana-Filho, Valter Joviniano

2017-01-01

OBJECTIVE: During cardiac surgery, several factors contribute to the development of postoperative pulmonary complications. Non-invasive ventilation is a promising therapeutic tool for improving the functionality of this type of patient. The aim of this study is to evaluate the functional capacity and length of stay of patients in a nosocomial intensive care unit who underwent prophylactic non-invasive ventilation after heart valve replacement. METHOD: The study was a controlled clinical trial, comprising 50 individuals of both sexes who were allocated by randomization into two groups with 25 patients in each group: the control group and experimental group. After surgery, the patients were transferred to the intensive care unit and then participated in standard physical therapy, which was provided to the experimental group after 3 applications of non-invasive ventilation within the first 26 hours after extubation. For non-invasive ventilation, the positive pressure was 10 cm H2O, with a duration of 1 hour. The evaluation was performed on the 7th postoperative day/discharge and included a 6-minute walk test. The intensive care unit and hospitalization times were monitored in both groups. Brazilian Registry of Clinical Trials (REBeC): RBR number 8bxdd3. RESULTS: Analysis of the 6-minute walk test showed that the control group walked an average distance of 264.34±76 meters and the experimental group walked an average distance of 334.07±71 meters (p=0.002). The intensive care unit and hospitalization times did not differ between the groups. CONCLUSION: Non-invasive ventilation as a therapeutic resource was effective toward improving functionality; however, non-invasive ventilation did not influence the intensive care unit or hospitalization times of the studied cardiac patients. PMID:29160424

Family clustering of secondary chronic kidney disease with hypertension or diabetes mellitus. A case-control study.

PubMed

de Almeida, Fernando Antonio; Ciambelli, Giuliano Serafino; Bertoco, André Luz; Jurado, Marcelo Mai; Siqueira, Guilherme Vasconcelos; Bernardo, Eder Augusto; Pavan, Maria Valeria; Gianini, Reinaldo José

2015-02-01

In Brazil hypertension and type 2 diabetes mellitus are responsible for 60% of cases of end-stage renal disease in renal replacement therapy. In the United States studies have identified family clustering of chronic kidney disease, predominantly in African-Americans. A single Brazilian study observed family clustering among patients with chronic kidney disease when compared with hospitalized patients with normal renal function. This article aims to assess whether there is family clustering of chronic kidney disease in relatives of individuals in renal replacement therapy caused by hypertension and/or diabetes mellitus. A case-control study with 336 patients in renal replacement therapy with diabetes mellitus or hypertension for at least 5 years (cases) and a control matched sample group of individuals with hypertension or diabetes mellitus and normal renal function (n = 389). Individuals in renal replacement therapy (cases) had a ratio of 2.35 (95% CI 1.42-3.89, p < 0.001) versus the control group in having relatives with chronic renal disease, irrespective of race or causative illness. There is family clustering of chronic kidney disease in the sample studied, and this predisposition is irrespective of race and underlying disease (hypertension or diabetes mellitus).

Recent Advances in Hydrocortisone Replacement Treatment.

PubMed

Mallappa, Ashwini; Debono, Miguel

2016-01-01

Since the first use of cortisone in patients around 65 years ago, the use of synthetic glucocorticoids has made a crucial impact on the treatment of several diseases in medicine. Although significant reductions in morbidity and mortality have occurred in patients suffering from cortisol deficiency, conventional hydrocortisone replacement treatment is still inadequate. A major limitation is that it fails to replace cortisol in a physiological manner. Cortisol has a distinct circadian rhythm and acts as a secondary messenger synchronizing the central to peripheral clocks, hence playing a key role in biological processes and the circadian timing system. Circadian misalignment has been associated with ill-health and so nonphysiological glucocorticoid treatment could explain the increased mortality rate, poor quality of life and metabolic complications in patients suffering from adrenal insufficiency. Attempts at replacing cortisol in a physiological manner have shown significant progress in the past decade with the development of modified-release formulations of hydrocortisone (Chronocort® and Plenadren®) and continuous subcutaneous hydrocortisone infusions. Initial studies investigating the use of these replacement regimens are promising, demonstrating both clinical and biochemical improvement. Larger studies are needed to determine whether this novel approach enhances long-term outcomes in both children and adults with cortisol deficiency. This is a work of the U.S. Government and is not subject to copyright protection in the United States. Foreign copyrights may apply. Published by S. Karger AG, Basel.

Geographic disparities in patient travel for dialysis in the United States.

PubMed

Stephens, J Mark; Brotherton, Samuel; Dunning, Stephan C; Emerson, Larry C; Gilbertson, David T; Harrison, David J; Kochevar, John J; McClellan, Ann C; McClellan, William M; Wan, Shaowei; Gitlin, Matthew

2013-01-01

To estimate travel distance and time for US hemodialysis patients and to compare travel of rural versus urban patients. Dialysis patient residences were estimated from ZIP code-level patient counts as of February 2011 allocated within the ZIP code proportional to census tract-level population, obtained from the 2010 U.S. Census. Dialysis facility addresses were obtained from Medicare public-use files. Patients were assigned to an "original" and "replacement" facility, assuming patients used the facility closest to home and would select the next closest facility as a replacement, if a replacement facility was required. Driving distances and times were calculated between patient residences and facility locations using GIS software. The mean one-way driving distance to the original facility was 7.9 miles; for rural patients average distances were 2.5 times farther than for urban patients (15.9 vs. 6.2 miles). Mean driving distance to a replacement facility was 10.6 miles, with rural patients traveling on average 4 times farther than urban patients to a replacement facility (28.8 vs. 6.8 miles). Rural patients travel much longer distances for dialysis than urban patients. Accessing alternative facilities, if required, would greatly increase rural patient travel, while having little impact on urban patients. Increased travel could have clinical implications as longer travel is associated with increased mortality and decreased quality of life. © 2013 National Rural Health Association.

Purification, crystallization and preliminary crystallographic analysis of a 6-pyruvoyltetrahydropterin synthase homologue from Esherichia coli.

PubMed

Seo, Kyung Hye; Supangat; Kim, Hye Lim; Park, Young Shik; Jeon, Che Ok; Lee, Kon Ho

2008-02-01

6-Pyruvoyltetrahydropterin synthase from E. coli (ePTPS) has been crystallized using the hanging-drop vapour-diffusion method. Hexagonal- and rectangular-shaped crystals were obtained. Diffraction data were collected from the hexagonal and rectangular crystals to 3.0 and 2.3 A resolution, respectively. The hexagonal plate-shaped crystals belonged to space group P321, with unit-cell parameters a = b = 112.59, c = 68.82 A , and contained two molecules in the asymmetric unit. The rectangular crystals belonged to space group I222, with unit-cell parameters a = 112.76, b = 117.66, c = 153.57 A , and contained six molecules in the asymmetric unit. The structure of ePTPS in both crystal forms has been determined by molecular replacement.

Purification, crystallization and preliminary crystallographic analysis of a 6-pyruvoyltetrahydropterin synthase homologue from Esherichia coli

PubMed Central

Seo, Kyung Hye; Supangat; Kim, Hye Lim; Park, Young Shik; Jeon, Che Ok; Lee, Kon Ho

2008-01-01

6-Pyruvoyltetrahydropterin synthase from E. coli (ePTPS) has been crystallized using the hanging-drop vapour-diffusion method. Hexagonal- and rectangular-shaped crystals were obtained. Diffraction data were collected from the hexagonal and rectangular crystals to 3.0 and 2.3 Å resolution, respectively. The hexagonal plate-shaped crystals belonged to space group P321, with unit-cell parameters a = b = 112.59, c = 68.82 Å, and contained two molecules in the asymmetric unit. The rectangular crystals belonged to space group I222, with unit-cell parameters a = 112.76, b = 117.66, c = 153.57 Å, and contained six molecules in the asymmetric unit. The structure of ePTPS in both crystal forms has been determined by molecular replacement. PMID:18271114

Failure Analysis of Nonvolatile Residue (NVR) Analyzer Model SP-1000

NASA Technical Reports Server (NTRS)

Potter, Joseph C.

2011-01-01

National Aeronautics and Space Administration (NASA) subcontractor Wiltech contacted the NASA Electrical Lab (NE-L) and requested a failure analysis of a Solvent Purity Meter; model SP-IOOO produced by the VerTis Instrument Company. The meter, used to measure the contaminate in a solvent to determine the relative contamination on spacecraft flight hardware and ground servicing equipment, had been inoperable and in storage for an unknown amount of time. NE-L was asked to troubleshoot the unit and make a determination on what may be required to make the unit operational. Through the use of general troubleshooting processes and the review of a unit in service at the time of analysis, the unit was found to be repairable but would need the replacement of multiple components.

Applied Meteorology Unit (AMU) Quarterly Report Third Quarter FY-08

NASA Technical Reports Server (NTRS)

Bauman, William; Crawford, Winifred; Barrett, Joe; Watson, Leela; Dreher, Joseph

2008-01-01

This report summarizes the Applied Meteorology Unit (AMU) activities for the third quarter of Fiscal Year 2008 (April - June 2008). Tasks reported on are: Peak Wind Tool for User Launch Commit Criteria (LCC), Anvil Forecast Tool in AWIPS Phase II, Completion of the Edward Air Force Base (EAFB) Statistical Guidance Wind Tool, Volume Averaged Height Integ rated Radar Reflectivity (VAHIRR), Impact of Local Sensors, Radar Scan Strategies for the PAFB WSR-74C Replacement, VAHIRR Cost Benefit Analysis, and WRF Wind Sensitivity Study at Edwards Air Force Base

KSC-2009-2517

NASA Image and Video Library

2009-04-02

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center in Florida, a technician prepares the Science Instrument Command and Data Handling Unit, or SIC&DH, for its move to the Multi-Use Lightweight Equipment Carrier in the facility. The SIC&DH will be installed on the Hubble Space Telescope during space shuttle Atlantis' STS-125 mission. This unit will replace the one that suffered a failure aboard the orbiting telescope on Sept. 27, 2008. Atlantis is targeted for launch on May 12. Photo credit: NASA/Dimitri Gerondidakis

KSC-2009-2516

NASA Image and Video Library

2009-04-02

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center in Florida, technicians look over the Science Instrument Command and Data Handling Unit, or SIC&DH. The SIC&DH will be installed on the Multi-Use Lightweight Equipment Carrier in the facility. The SIC&DH will be installed on the Hubble Space Telescope during space shuttle Atlantis' STS-125 mission. This unit will replace the one that suffered a failure aboard the orbiting telescope on Sept. 27, 2008. Atlantis is targeted for launch on May 12. Photo credit: NASA/Dimitri Gerondidakis

KSC-2009-2519

NASA Image and Video Library

2009-04-02

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center in Florida, the Science Instrument Command and Data Handling Unit, or SIC&DH, is moved toward the Multi-Use Lightweight Equipment Carrier in the background, where it will be installed. The SIC&DH will be installed on the Hubble Space Telescope during space shuttle Atlantis' STS-125 mission. This unit will replace the one that suffered a failure aboard the orbiting telescope on Sept. 27, 2008. Atlantis is targeted for launch on May 12. Photo credit: NASA/Dimitri Gerondidakis

KSC-2009-2518

NASA Image and Video Library

2009-04-02

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center in Florida, the Science Instrument Command and Data Handling Unit, or SIC&DH, is moved toward the Multi-Use Lightweight Equipment Carrier in the background, where it will be installed. The SIC&DH will be installed on the Hubble Space Telescope during space shuttle Atlantis' STS-125 mission. This unit will replace the one that suffered a failure aboard the orbiting telescope on Sept. 27, 2008. Atlantis is targeted for launch on May 12. Photo credit: NASA/Dimitri Gerondidakis

Synthesis and structure of [Na11(OtBu)10(OH)]: 1H NMR shift of a hydroxide ion encapsulated in a 21-vertex alcoholate cage.

PubMed

Geier, Jens; Grützmacher, Hansjörg

2003-12-07

[Na11(OtBu)10(OH)], a hydroxide enclosing 21-vertex cage compound, was found to crystallize from mixtures of sodium tert.butanolate with sodium hydroxide. Its structure can be derived from the known (NaOtBu)6-hexaprismane by replacing one butanolate unit with OH- and capping the latter with five additional units of NaOtBu. The hydroxide shows a signal at -3.21 ppm in the 1H NMR spectrum.

Cloning, expression, purification, crystallization and preliminary X-ray studies of argininosuccinate lyase (Rv1659) from Mycobacterium tuberculosis

PubMed Central

Paul, A.; Mishra, A.; Surolia, A.; Vijayan, M.

2013-01-01

The last enzyme in the arginine-biosynthesis pathway, argininosuccinate lyase, from Mycobacterium tuberculosis has been cloned, expressed, purified and crystallized, and preliminary X-ray studies have been carried out on the crystals. The His-tagged tetrameric enzyme with a subunit molecular weight of 50.9 kDa crystallized with two tetramers in the asymmetric unit of the orthorhombic unit cell, space group P212121. Molecular-replacement calculations and self-rotation calculations confirmed the space group and the tetrameric nature of the molecule. PMID:24316845

On Pythagoras Theorem for Products of Spectral Triples

NASA Astrophysics Data System (ADS)

D'Andrea, Francesco; Martinetti, Pierre

2013-05-01

We discuss a version of Pythagoras theorem in noncommutative geometry. Usual Pythagoras theorem can be formulated in terms of Connes' distance, between pure states, in the product of commutative spectral triples. We investigate the generalization to both non-pure states and arbitrary spectral triples. We show that Pythagoras theorem is replaced by some Pythagoras inequalities, that we prove for the product of arbitrary (i.e. non-necessarily commutative) spectral triples, assuming only some unitality condition. We show that these inequalities are optimal, and we provide non-unital counter-examples inspired by K-homology.

A further step towards tuning the properties of metal-chalcogenide nanocapsules by replacing skeletal oxide by sulphide ligands.

PubMed

Schäffer, Christian; Todea, Ana Maria; Bögge, Hartmut; Floquet, Sébastien; Cadot, Emmanuel; Korenev, Vladimir S; Fedin, Vladimir P; Gouzerh, Pierre; Müller, Achim

2013-01-14

Addition of [Mo(2)(V)O(2)(μ-O)(μ-S)(aq)](2+) linker-type units to a solution/dynamic library containing tungstates results via the formation of the complementary pentagonal {(W)W(5)} units logically in the self-assembly of a mixed oxide/sulphide {W(VI)(72)Mo(V)(60)}-type Keplerate, thereby demonstrating the ability to tune the capsule's skeletal softness (the (μ-O)(2) and (μ-S)(2) scenarios are known) and providing options to influence differently important capsule-substrate interactions.

EVA 3 - Linnehan and Grunsfeld install new PCU

NASA Image and Video Library

2002-03-06

STS109-E-5660 (6 March 2002) --- Astronauts John M. Grunsfeld (top) and Richard M. Linnehan participate in a 6 hour, 48 minute space walk designed to install a new Power Control Unit (PCU) on the Hubble Space Telescope (HST). The two went on to replace the original unit launched with the telescope in April 1990. Grunsfeld is on the end of Columbia's Remote Manipulator System (RMS) robotic arm, controlled from inside the crew cabin by astronaut Nancy J. Currie. The image was recorded with a digital still camera.

The effect of replacing pnictogen elements on the physical properties SrMg2 {{\\boldsymbol{X}}}_{2} ({\\boldsymbol{X}}=N, P, As, Sb, Bi) Zintl compounds

NASA Astrophysics Data System (ADS)

Murtaza, G.; Ahad Khan, Abdul; Yaseen, M.; Laref, A.; Ullah, Naeem; Rahman, Inayat ur

2018-04-01

Not Available Project supported by a grant from the “Research Center of Female Scientific and Medical Colleges”, the Deanship of Scientific Research, King Saud University. Yaseen M is thankful to Higher Education Commission (HEC), Pakistan for funding (Grant No. 6410/Punjab/NRPU/R&D/HEC/2016), and also this study is made possible by the support of the United States Government and the American people through the United States Agency for International Development (USAID). The contents are the sole responsibility of National University of Sciences and Technology and do not necessarily reflect the views of USAID or the United States Government.

The Loma Prieta, California, Earthquake of October 17, 1989: Performance of the Built Environment

USGS Publications Warehouse

Coordinated by Holzer, Thomas L.

1998-01-01

Professional Paper 1552 focuses on the response of buildings, lifelines, highway systems, and earth structures to the earthquake. Losses to these systems totaled approximated $5.9 billion. The earthquake displaced many residents from their homes and severely disrupted transportation systems. Some significant findings were: * Approximately 16,000 housing units were uninhabitable after the earthquake including 13,000 in the San Francisco Bay region. Another 30,000-35,000 units were moderately damaged in the earthquake. Renters and low-income residents were particularly hard hit. * Failure of highway systems was the single largest cause of loss of life during the earthquake. Forty-two of the 63 earthquake fatalities died when the Cypress Viaduct in Oakland collapsed. The cost to repair and replace highways damaged by the earthquake was $2 billion, about half of which was to replace the Cypress Viaduct. * Major bridge failures were the result of antiquated designs and inadequate anticipation of seismic loading. * Twenty one kilometers (13 mi) of gas-distribution lines had to be replaced in several communities and more than 1,200 leaks and breaks in water mains and service connections had to be excavated and repaired. At least 5 electrical substations were badly damaged, overwhelming the designed redundancy of the electrical system. * Instruments in 28 buildings recorded their response to earthquake shaking that provided opportunities to understand how different types of buildings responded, the importance of site amplification, and how buildings interact with their foundation when shaken (soil structure interaction).

Acute dialysis-associated peritonitis in children with D+ hemolytic uremic syndrome.

PubMed

Adragna, Marta; Balestracci, Alejandro; García Chervo, Laura; Steinbrun, Silvina; Delgado, Norma; Briones, Liliana

2012-04-01

Acute peritoneal dialysis (PD) is the preferred therapy for renal replacement in children with post-diarrheal hemolytic uremic syndrome (D+ HUS), but peritonitis remains a frequent complication of this procedure. We reviewed data from 149 patients with D+ HUS who had undergone acute PD with the aim of determining the prevalence and risk factors for the development of peritonitis. A total of 36 patients (24.2%) presented peritonitis. The median onset of peritonitis manifestations was 6 (range 2-18) days after the initiation of dialysis treatment, and Gram-positive microorganisms were the predominant bacterial type isolated (15/36 patients). The patients were divided into two groups: with or without peritonitis, respectively. Univariate analysis revealed that a longer duration of the oligoanuric period, more days of dialysis, catheter replacement, stay in the intensive care unit, and hypoalbuminemia were significantly associated to the development of peritonitis. The multivariate analysis, controlled by duration of PD, identified the following independent risk factors for peritonitis: catheter replacement [p = 0.037, odds ratio (OR) 1.33, 95% confidence interval (CI) 1.02-1.73], stay in intensive care unit (p = 0.0001, OR 2.62, 95% CI 1.65-4.19), and hypoalbuminemia (p = 0.0076, OR 1.45, 95% CI 1.10-1.91). Based on these findings, we conclude that the optimization of the aseptic technique during catheter manipulation and early nutritional support are targets for the prevention of peritonitis, especially in critically ill patients.

High Efficiency Room Air Conditioner

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bansal, Pradeep

This project was undertaken as a CRADA project between UT-Battelle and Geberal Electric Company and was funded by Department of Energy to design and develop of a high efficiency room air conditioner. A number of novel elements were investigated to improve the energy efficiency of a state-of-the-art WAC with base capacity of 10,000 BTU/h. One of the major modifications was made by downgrading its capacity from 10,000 BTU/hr to 8,000 BTU/hr by replacing the original compressor with a lower capacity (8,000 BTU/hr) but high efficiency compressor having an EER of 9.7 as compared with 9.3 of the original compressor. However,more » all heat exchangers from the original unit were retained to provide higher EER. The other subsequent major modifications included- (i) the AC fan motor was replaced by a brushless high efficiency ECM motor along with its fan housing, (ii) the capillary tube was replaced with a needle valve to better control the refrigerant flow and refrigerant set points, and (iii) the unit was tested with a drop-in environmentally friendly binary mixture of R32 (90% molar concentration)/R125 (10% molar concentration). The WAC was tested in the environmental chambers at ORNL as per the design rating conditions of AHAM/ASHRAE (Outdoor- 95F and 40%RH, Indoor- 80F, 51.5%RH). All these modifications resulted in enhancing the EER of the WAC by up to 25%.« less

Multistate Outbreak of Salmonella Virchow Infections Linked to a Powdered Meal Replacement Product - United States, 2015-2016.

PubMed

Gambino-Shirley, Kelly J; Tesfai, Adiam; Schwensohn, Colin A; Burnett, Cindy; Smith, Lori; Wagner, Jennifer M; Eikmeier, Dana; Smith, Kirk; Stone, Jolianne P; Updike, Dawn; Hines, Jonas; Shade, Lauren N; Tolar, Beth; Fu, Tong-Jen; Viazis, Stelios; Seelman, Sharon L; Blackshear, Kathryn; Wise, Matthew E; Neil, Karen P

2018-03-07

Nontyphoidal Salmonella is the leading cause of bacterial gastroenteritis in the United States. Meal replacement products containing raw and 'superfood' ingredients have gained increasing popularity among consumers in recent years. In January 2016, we investigated a multistate outbreak of infections with a novel strain of Salmonella Virchow. Cases were defined using molecular subtyping procedures. Commonly reported exposures were compared with responses from healthy people interviewed in the 2006-2007 FoodNet Population Survey. Firm inspections and product traceback and testing were performed. Thirty-five cases from 24 states were identified; 6 hospitalizations and no deaths were reported. Thirty-one (94%) of 33 ill people interviewed reported consuming a powdered supplement in the week before illness; of these, 30 (97%) reported consuming Product A, a raw organic powdered shake product consumed as a meal replacement. Laboratory testing isolated the outbreak strain of Salmonella Virchow from: leftover Product A collected from ill people's homes, organic moringa leaf powder (an ingredient in Product A), and finished product retained by the firm. Firm inspections at three facilities linked to Product A production did not reveal contamination at the facilities. Traceback identified that the contaminated moringa leaf powder was imported from South Africa. This investigation identified a novel outbreak vehicle and highlighted the potential risk with similar products not intended to be cooked by consumers before consuming. The company issued a voluntary recall of all implicated products. As this product has a long shelf-life, the recall likely prevented additional illnesses.

Aortic valve replacement and concomitant right coronary artery bypass grafting performed via a right minithoracotomy approach.

PubMed

Mihos, Christos G; Santana, Orlando; Pineda, Andres M; La Pietra, Angelo; Lamelas, Joseph

2014-01-01

We present our experience of concomitant right coronary artery bypass grafting (CABG) and aortic valve replacement performed via a right minithoracotomy in patients with coronary lesions not amenable to percutaneous intervention. A total of 17 patients underwent concomitant aortic valve replacement and right CABG between April 2008 and July 2013. A 5- to 6-cm minithoracotomy incision was made over the right second or third intercostal space, and the costochondral cartilage was transected. A saphenous vein bypass to the right coronary artery was then performed, initiating the anastomosis from the toe of the graft. Subsequently, the aortic valve was replaced using standard techniques. There were 6 men and 11 women. The median European System for Cardiac Operative Risk Evaluation II score mortality risk was 5% [interquartile range (IQR), 2%-8%]. The mean (SD) age was 77 (10) years, the left ventricular ejection fraction was 59% (8%), and the New York Heart Association functional class was 2.4 (0.8). One patient had a history of CABG. The mean (SD) cardiopulmonary bypass time was 168 (57) minutes, and the aortic cross-clamp time was 133 (36) minutes. Three patients underwent concomitant mitral valve surgery (replacement, 2; repair, 1). The median intensive care unit and hospital lengths of stay were 47 hours (IQR, 24-90) and 9 days (IQR, 5-13), respectively. There was one reoperation for bleeding, and there was one postoperative stroke. All patients were alive at a mean (SD) follow-up of 2 (1.1) years. Aortic valve replacement with concomitant CABG performed via a right minithoracotomy approach is feasible.

A dented LH2 recirculation line is removed from Discovery

NASA Technical Reports Server (NTRS)

1999-01-01

Workers with United Space Alliance remove Shuttle Discovery's dented main propulsion system liquid hydrogen recirculation line. From left are James Stickley, George Atkins, and Todd Biddle. The 12-inch-long dent was discovered during routine aft compartment inspections Tuesday, Dec. 7. The line recirculates hydrogen from the Shuttle main engines back to the external tank during prelaunch engine conditioning. The line is being replaced and managers expect the replacement work to take about 3 days, followed by system retests and final aft compartment close-outs. Preliminary assessments reflect a launch date of Space Shuttle Discovery on mission STS-103 no earlier than Dec. 16. STS-103 is the third servicing mission for the Hubble Space Telescope.

ISS ECLSS: 3 Years of Logistics for Maintenance

NASA Technical Reports Server (NTRS)

Shkedi, Brienne; Thompson, Dean

2004-01-01

The International Space Station (ISS) Environmental Control and Life Support System (ECLSS) is designed to be maintainable. During the 3 years since the ISS US Lab became operational, there have been numerous ECLSS Orbital Replacement Units (ORUs) launched and returned to Maintain the ECLSS operation in the US segments. The maintenance logistics have provided tools for maintenance, replaced limited life ORUs and failed ORUs, upgraded ECLSS hardware to improve reliability and placed critical spares onboard prior to need. In most cases, the removed ORUs have been returned for either failure analysis and repair or refurbishment. This paper describes the ECLSS manifesting history and maintenance events and quantifies the numbers of ECLSS items, weights, and volumes.

KSC-04PD-2677

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. Before a road test of the Crawler Transporter, United Space Alliance Vice President, Associate Program Manager of Florida Operations, Bill Pickavance (in front), look at the controls of the cab. The Crawler Transporter that will move Space Shuttle Discovery to the launch pad for Return to Flight is taking its first road test following the replacement of all its shoes. The crawlers have 456 shoes, 57 per belt (8 belts in all). Each shoe weighs 2,200 pounds. Cracks appeared in the shoes in recent years, spurring a need for replacement. The new manufacturer, in Duluth, Minn., has improved the design for a safe Return to Flight and use through the balance of the Space Shuttle Program.

KSC-08pd2100

NASA Image and Video Library

2008-07-21

CAPE CANAVERAL, Fla. --CAPE CANAVERAL, Fla. -- In the high bay of the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, three carriers are undergoing processing for space shuttle Atlantis' STS-125 mission to service the Hubble Space Telescope. From left are the Flight Support System or FSS, the Orbital Replacement Unit Carrier or ORUC, and the Super Lightweight Interchangeable Carrier or SLIC. The Multi-Use Lightweight Equipment carrier will be delivered in early August. The carriers will be prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the Hubble servicing mission, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2099

NASA Image and Video Library

2008-07-21

CAPE CANAVERAL, Fla. -- In the high bay of the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, this elevated view shows three carriers undergoing processing for space shuttle Atlantis' STS-125 mission to service the Hubble Space Telescope. From left are the Flight Support System or FSS, the Orbital Replacement Unit Carrier or ORUC, and the Super Lightweight Interchangeable Carrier or SLIC. The Multi-Use Lightweight Equipment carrier will be delivered in early August. The carriers will be prepared for the integration of telescope science instruments, both internal and external replacement components, as well as the flight support equipment to be used by the astronauts during the Hubble servicing mission, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2151

NASA Image and Video Library

2008-07-26

CAPE CANAVERAL, Fla. – Inside Orbiter Processing Facility 2 at NASA's Kennedy Space Center, United Space Alliance technicians install Boeing Replacement Insulation 18, or BRI-18, tile on space shuttle Endeavour during processing activities. BRI-18 is the strongest material used for thermal insulation on the orbiters and, when coated to produce toughened unipiece fibrous insulation, provides a tile with extremely high-impact resistance. It is replacing other tiles on areas of the vehicle where impact risk is high, such as the landing gear doors, the wing leading edge and the external tank doors. Endeavour will deliver a multi-purpose logistics module to the International Space Station on its STS-126 mission. Launch is targeted for Nov. 10. Photo credit: NASA/Jack Pfaller