Sample records for represent physiological remnants

  1. Physiological and biochemical basis of clinical liver function tests: a review.

    PubMed

    Hoekstra, Lisette T; de Graaf, Wilmar; Nibourg, Geert A A; Heger, Michal; Bennink, Roelof J; Stieger, Bruno; van Gulik, Thomas M

    2013-01-01

    To review the literature on the most clinically relevant and novel liver function tests used for the assessment of hepatic function before liver surgery. Postoperative liver failure is the major cause of mortality and morbidity after partial liver resection and develops as a result of insufficient remnant liver function. Therefore, accurate preoperative assessment of the future remnant liver function is mandatory in the selection of candidates for safe partial liver resection. A MEDLINE search was performed using the key words "liver function tests," "functional studies in the liver," "compromised liver," "physiological basis," and "mechanistic background," with and without Boolean operators. Passive liver function tests, including biochemical parameters and clinical grading systems, are not accurate enough in predicting outcome after liver surgery. Dynamic quantitative liver function tests, such as the indocyanine green test and galactose elimination capacity, are more accurate as they measure the elimination process of a substance that is cleared and/or metabolized almost exclusively by the liver. However, these tests only measure global liver function. Nuclear imaging techniques ((99m)Tc-galactosyl serum albumin scintigraphy and (99m)Tc-mebrofenin hepatobiliary scintigraphy) can measure both total and future remnant liver function and potentially identify patients at risk for postresectional liver failure. Because of the complexity of liver function, one single test does not represent overall liver function. In addition to computed tomography volumetry, quantitative liver function tests should be used to determine whether a safe resection can be performed. Presently, (99m)Tc-mebrofenin hepatobiliary scintigraphy seems to be the most valuable quantitative liver function test, as it can measure multiple aspects of liver function in, specifically, the future remnant liver.

  2. Visuo-manual tracking: does intermittent control with aperiodic sampling explain linear power and non-linear remnant without sensorimotor noise?

    PubMed

    Gollee, Henrik; Gawthrop, Peter J; Lakie, Martin; Loram, Ian D

    2017-11-01

    A human controlling an external system is described most easily and conventionally as linearly and continuously translating sensory input to motor output, with the inevitable output remnant, non-linearly related to the input, attributed to sensorimotor noise. Recent experiments show sustained manual tracking involves repeated refractoriness (insensitivity to sensory information for a certain duration), with the temporary 200-500 ms periods of irresponsiveness to sensory input making the control process intrinsically non-linear. This evidence calls for re-examination of the extent to which random sensorimotor noise is required to explain the non-linear remnant. This investigation of manual tracking shows how the full motor output (linear component and remnant) can be explained mechanistically by aperiodic sampling triggered by prediction error thresholds. Whereas broadband physiological noise is general to all processes, aperiodic sampling is associated with sensorimotor decision making within specific frontal, striatal and parietal networks; we conclude that manual tracking utilises such slow serial decision making pathways up to several times per second. The human operator is described adequately by linear translation of sensory input to motor output. Motor output also always includes a non-linear remnant resulting from random sensorimotor noise from multiple sources, and non-linear input transformations, for example thresholds or refractory periods. Recent evidence showed that manual tracking incurs substantial, serial, refractoriness (insensitivity to sensory information of 350 and 550 ms for 1st and 2nd order systems respectively). Our two questions are: (i) What are the comparative merits of explaining the non-linear remnant using noise or non-linear transformations? (ii) Can non-linear transformations represent serial motor decision making within the sensorimotor feedback loop intrinsic to tracking? Twelve participants (instructed to act in three prescribed ways) manually controlled two systems (1st and 2nd order) subject to a periodic multi-sine disturbance. Joystick power was analysed using three models, continuous-linear-control (CC), continuous-linear-control with calculated noise spectrum (CCN), and intermittent control with aperiodic sampling triggered by prediction error thresholds (IC). Unlike the linear mechanism, the intermittent control mechanism explained the majority of total power (linear and remnant) (77-87% vs. 8-48%, IC vs. CC). Between conditions, IC used thresholds and distributions of open loop intervals consistent with, respectively, instructions and previous measured, model independent values; whereas CCN required changes in noise spectrum deviating from broadband, signal dependent noise. We conclude that manual tracking uses open loop predictive control with aperiodic sampling. Because aperiodic sampling is inherent to serial decision making within previously identified, specific frontal, striatal and parietal networks we suggest that these structures are intimately involved in visuo-manual tracking. © 2017 The Authors. The Journal of Physiology published by John Wiley & Sons Ltd on behalf of The Physiological Society.

  3. Life threatening bleeding from duodenal ulcer after Roux-en-Y gastric bypass: Case report and review of the literature.

    PubMed

    Ivanecz, Arpad; Sremec, Marko; Ceranić, Davorin; Potrč, Stojan; Skok, Pavel

    2014-12-16

    Acute upper gastrointestinal bleeding is a rare, but serious complication of gastric bypass surgery. The inaccessibility of the excluded stomach restrains postoperative examination and treatment of the gastric remnant and duodenum, and represents a major challenge, especially in the emergency setting. A 59-year-old patient with previous history of peptic ulcer disease had an upper gastrointestinal bleeding from a duodenal ulcer two years after having a gastric bypass procedure for morbid obesity. After negative upper endoscopy finding, he was urgently evaluated for gastrointestinal bleeding. At emergency laparotomy, the bleeding duodenal ulcer was identified by intraoperative endoscopy through gastrotomy. The patient recovered well after surgical hemostasis, excision of the duodenal ulcer and completion of the remnant gastrectomy. Every general practitioner, gastroenterologist and general surgeon should be aware of growing incidence of bariatric operations and coherently possible complications after such procedures, which modify patient's anatomy and physiology.

  4. Life threatening bleeding from duodenal ulcer after Roux-en-Y gastric bypass: Case report and review of the literature

    PubMed Central

    Ivanecz, Arpad; Sremec, Marko; Ćeranić, Davorin; Potrč, Stojan; Skok, Pavel

    2014-01-01

    Acute upper gastrointestinal bleeding is a rare, but serious complication of gastric bypass surgery. The inaccessibility of the excluded stomach restrains postoperative examination and treatment of the gastric remnant and duodenum, and represents a major challenge, especially in the emergency setting. A 59-year-old patient with previous history of peptic ulcer disease had an upper gastrointestinal bleeding from a duodenal ulcer two years after having a gastric bypass procedure for morbid obesity. After negative upper endoscopy finding, he was urgently evaluated for gastrointestinal bleeding. At emergency laparotomy, the bleeding duodenal ulcer was identified by intraoperative endoscopy through gastrotomy. The patient recovered well after surgical hemostasis, excision of the duodenal ulcer and completion of the remnant gastrectomy. Every general practitioner, gastroenterologist and general surgeon should be aware of growing incidence of bariatric operations and coherently possible complications after such procedures, which modify patient’s anatomy and physiology. PMID:25512773

  5. Kepler Supernova Remnant: A View from Hubble Space Telescope

    NASA Image and Video Library

    2004-10-06

    This image represents a view of NASA Kepler supernova remnant taken in X-rays, visible light, and infrared radiation, indicating that the bubble of gas that makes up the supernova remnant appears different in various types of light. http://photojournal.jpl.nasa.gov/catalog/PIA06909

  6. Exploring the X-ray Morphology of the Supernova Remnant Kes 27 using Numerical Simulations

    NASA Astrophysics Data System (ADS)

    Dwarkadas, Vikram; Dewey, D.

    2013-04-01

    Kesteven 27 is a member of the class of thermal composite or mixed-morphology remnants, which can show thermal X-ray emission extending all the way in towards the center. The Chandra image shows two incomplete shell-like features in the north-eastern half, with brightness fading towards the southwest. The X-ray and radio structure led Chen et al. (2008) to suggest that the morphology represents a supernova remnant expanding in a windblown bubble. The two X-ray rings represent the outer shock of the supernova remnant, and a reflected shock arising from collision with a dense shell. Using numerical simulations followed by a computation of the X-ray emission, we explore this possibility. Our initial modeling suggests that the scenario discussed by Chen et al. (2008) may not work. We suggest and discuss modifications to this scenario that may be able to reproduce the observed morphology, and the implications for thermal composite remnants.

  7. 31 CFR 100.7 - Treasury's liability.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... made when: (1) Fragments and remnants presented are not identifiable as United States currency; or (2) Fragments and remnants presented which represent 50% or less of a note are identifiable as United States...

  8. Hypercementosis and odontogenic epithelial hyperplasia associated with a tooth root remnant mimicking a neoplasm. A case report.

    PubMed

    Zustin, J; Friedrich, R E

    2010-01-01

    Hypercementosis presents as painless, single or multiple non-neoplastic cementum formation beyond the physiological limits of the tooth. It often occurs in the apical area of the involved tooth following infection, chemical or mechanical trauma. We report on radiographic and histopathological findings in a single case of late intraosseous hypercementosis and odontogenic epithelial hyperplasia associated with a minute apical tooth root remnant years after its extraction, mimicking a tumour.

  9. The presence of dysplastic nevus remnants in malignant melanomas. A population-based study of 551 malignant melanomas.

    PubMed

    Hastrup, N; Osterlind, A; Drzewiecki, K T; Hou-Jensen, K

    1991-08-01

    We examined 512 malignant melanomas, representing all newly diagnosed cutaneous malignant melanomas, excluding lentigo maligna melanomas, from the period October 1, 1982 to March 31, 1985 occurring in the region of eastern Denmark in patients aged 20-79 years for the presence of dysplastic nevus remnants. Criteria for the diagnosis of a dysplastic nevus remnant include all the following changes (a) lentiginous or epithelioid melanocyte hyperplasia, (b) cytologic melanocyte atypia, (c) eosinophilic fibroplasia, (d) lamellar fibroplasia, and (e) lymphocytic infiltration in the dermis. Dysplastic nevus remnants were found in association with 34 (7%) of the evaluable 512 malignant melanomas. Fourteen (41%) of the remnants were of compound nevus type. In nine (27%) of the remnants, atypia was pronounced. Most (62%) dysplastic nevus remnants were contiguous to thin superficial spreading melanomas. We conclude from this population-based study that about 7% of malignant melanomas arise in prior dysplastic nevi.

  10. Visuo‐manual tracking: does intermittent control with aperiodic sampling explain linear power and non‐linear remnant without sensorimotor noise?

    PubMed Central

    Gawthrop, Peter J.; Lakie, Martin; Loram, Ian D.

    2017-01-01

    Key points A human controlling an external system is described most easily and conventionally as linearly and continuously translating sensory input to motor output, with the inevitable output remnant, non‐linearly related to the input, attributed to sensorimotor noise.Recent experiments show sustained manual tracking involves repeated refractoriness (insensitivity to sensory information for a certain duration), with the temporary 200–500 ms periods of irresponsiveness to sensory input making the control process intrinsically non‐linear.This evidence calls for re‐examination of the extent to which random sensorimotor noise is required to explain the non‐linear remnant.This investigation of manual tracking shows how the full motor output (linear component and remnant) can be explained mechanistically by aperiodic sampling triggered by prediction error thresholds.Whereas broadband physiological noise is general to all processes, aperiodic sampling is associated with sensorimotor decision making within specific frontal, striatal and parietal networks; we conclude that manual tracking utilises such slow serial decision making pathways up to several times per second. Abstract The human operator is described adequately by linear translation of sensory input to motor output. Motor output also always includes a non‐linear remnant resulting from random sensorimotor noise from multiple sources, and non‐linear input transformations, for example thresholds or refractory periods. Recent evidence showed that manual tracking incurs substantial, serial, refractoriness (insensitivity to sensory information of 350 and 550 ms for 1st and 2nd order systems respectively). Our two questions are: (i) What are the comparative merits of explaining the non‐linear remnant using noise or non‐linear transformations? (ii) Can non‐linear transformations represent serial motor decision making within the sensorimotor feedback loop intrinsic to tracking? Twelve participants (instructed to act in three prescribed ways) manually controlled two systems (1st and 2nd order) subject to a periodic multi‐sine disturbance. Joystick power was analysed using three models, continuous‐linear‐control (CC), continuous‐linear‐control with calculated noise spectrum (CCN), and intermittent control with aperiodic sampling triggered by prediction error thresholds (IC). Unlike the linear mechanism, the intermittent control mechanism explained the majority of total power (linear and remnant) (77–87% vs. 8–48%, IC vs. CC). Between conditions, IC used thresholds and distributions of open loop intervals consistent with, respectively, instructions and previous measured, model independent values; whereas CCN required changes in noise spectrum deviating from broadband, signal dependent noise. We conclude that manual tracking uses open loop predictive control with aperiodic sampling. Because aperiodic sampling is inherent to serial decision making within previously identified, specific frontal, striatal and parietal networks we suggest that these structures are intimately involved in visuo‐manual tracking. PMID:28833126

  11. Putative Nanobacteria Represent Physiological Remnants and Culture By-Products of Normal Calcium Homeostasis

    PubMed Central

    Young, John D.; Young, Lena; Wu, Cheng-Yeu; Young, Andrew

    2009-01-01

    Putative living entities called nanobacteria (NB) are unusual for their small sizes (50–500 nm), pleomorphic nature, and accumulation of hydroxyapatite (HAP), and have been implicated in numerous diseases involving extraskeletal calcification. By adding precipitating ions to cell culture medium containing serum, mineral nanoparticles are generated that are morphologically and chemically identical to the so-called NB. These nanoparticles are shown here to be formed of amorphous mineral complexes containing calcium as well as other ions like carbonate, which then rapidly acquire phosphate, forming HAP. The main constituent proteins of serum-derived NB are albumin, fetuin-A, and apolipoprotein A1, but their involvement appears circumstantial since so-called NB from different body fluids harbor other proteins. Accordingly, by passage through various culture media, the protein composition of these particles can be modulated. Immunoblotting experiments reveal that antibodies deemed specific for NB react in fact with either albumin, fetuin-A, or both, indicating that previous studies using these reagents may have detected these serum proteins from the same as well as different species, with human tissue nanoparticles presumably absorbing bovine serum antigens from the culture medium. Both fetal bovine serum and human serum, used earlier by other investigators as sources of NB, paradoxically inhibit the formation of these entities, and this inhibition is trypsin-sensitive, indicating a role for proteins in this inhibitory process. Fetuin-A, and to a lesser degree albumin, inhibit nanoparticle formation, an inhibition that is overcome with time, ending with formation of the so-called NB. Together, these data demonstrate that NB are most likely formed by calcium or apatite crystallization inhibitors that are somehow overwhelmed by excess calcium or calcium phosphate found in culture medium or in body fluids, thereby becoming seeds for calcification. The structures described earlier as NB may thus represent remnants and by-products of physiological mechanisms used for calcium homeostasis, a concept which explains the vast body of NB literature as well as explains the true origin of NB as lifeless protein-mineralo entities with questionable role in pathogenesis. PMID:19198665

  12. Molecular composition and ultrastructure of Jurassic paravian feathers

    PubMed Central

    Lindgren, Johan; Sjövall, Peter; Carney, Ryan M.; Cincotta, Aude; Uvdal, Per; Hutcheson, Steven W.; Gustafsson, Ola; Lefèvre, Ulysse; Escuillié, François; Heimdal, Jimmy; Engdahl, Anders; Gren, Johan A.; Kear, Benjamin P.; Wakamatsu, Kazumasa; Yans, Johan; Godefroit, Pascal

    2015-01-01

    Feathers are amongst the most complex epidermal structures known, and they have a well-documented evolutionary trajectory across non-avian dinosaurs and basal birds. Moreover, melanosome-like microbodies preserved in association with fossil plumage have been used to reconstruct original colour, behaviour and physiology. However, these putative ancient melanosomes might alternatively represent microorganismal residues, a conflicting interpretation compounded by a lack of unambiguous chemical data. We therefore used sensitive molecular imaging, supported by multiple independent analytical tests, to demonstrate that the filamentous epidermal appendages in a new specimen of the Jurassic paravian Anchiornis comprise remnant eumelanosomes and fibril-like microstructures, preserved as endogenous eumelanin and authigenic calcium phosphate. These results provide novel insights into the early evolution of feathers at the sub-cellular level, and unequivocally determine that melanosomes can be preserved in fossil feathers. PMID:26311035

  13. Kepler's Supernova Remnant: A View from Chandra X-Ray Observatory

    NASA Technical Reports Server (NTRS)

    2004-01-01

    [figure removed for brevity, see original site]

    [figure removed for brevity, see original site] Figure 1

    Each top panel in the composite above shows the entire remnant. Each color in the composite represents a different region of the electromagnetic spectrum, from X-rays to infrared light. The X-ray and infrared data cannot be seen with the human eye. Astronomers have color-coded those data so they can be seen in these images.

    The bottom panels are close-up views of the remnant. In the bottom, center image, Hubble sees fine details in the brightest, densest areas of gas. The region seen in these images is outlined in the top, center panel.

    The images indicate that the bubble of gas that makes up the supernova remnant appears different in various types of light. Chandra reveals the hottest gas [colored blue and colored green], which radiates in X-rays. The blue color represents the higher-energy gas; the green, the lower-energy gas. Hubble shows the brightest, densest gas [colored yellow], which appears in visible light. Spitzer unveils heated dust [colored red], which radiates in infrared light.

  14. LOFAR discovery of a 700-kpc remnant radio galaxy at low redshift

    NASA Astrophysics Data System (ADS)

    Brienza, M.; Godfrey, L.; Morganti, R.; Vilchez, N.; Maddox, N.; Murgia, M.; Orru, E.; Shulevski, A.; Best, P. N.; Brüggen, M.; Harwood, J. J.; Jamrozy, M.; Jarvis, M. J.; Mahony, E. K.; McKean, J.; Röttgering, H. J. A.

    2016-01-01

    Context. Remnant radio galaxies represent the final dying phase of radio galaxy evolution in which the jets are no longer active. Remnants are rare in flux-limited samples, comprising at most a few percent. As a result of their rarity and because they are difficult to identify, this dying phase remains poorly understood and the luminosity evolution is largely unconstrained. Aims: Here we present the discovery and detailed analysis of a large (700 kpc) remnant radio galaxy with a low surface brightness that has been identified in LOFAR images at 150 MHz. Methods: By combining LOFAR data with new follow-up Westerbork observations and archival data at higher frequencies, we investigated the source morphology and spectral properties from 116 to 4850 MHz. By modelling the radio spectrum, we probed characteristic timescales of the radio activity. Results: The source has a relatively smooth, diffuse, amorphous appearance together with a very weak central compact core that is associated with the host galaxy located at z = 0.051. From our ageing and morphological analysis it is clear that the nuclear engine is currently switched off or, at most, active at a very low power state. We find that the source has remained visible in the remnant phase for about 60 Myr, significantly longer than its active phase of 15 Myr, despite being located outside a cluster. The host galaxy is currently interacting with another galaxy located at a projected separation of 15 kpc and a radial velocity offset of ~ 300 km s-1. This interaction may have played a role in the triggering and/or shut-down of the radio jets. Conclusions: The spectral shape of this remnant radio galaxy differs from most of the previously identified remnant sources, which show steep or curved spectra at low to intermediate frequencies. Our results demonstrate that remnant radio galaxies can show a wide range of evolutionary paths and spectral properties. In light of this finding and in preparation for new-generation deep low-frequency surveys, we discuss the selection criteria to be used to select representative samples of these sources.

  15. Variation in diel activity of ground beetles (Coleoptera: Carabidae) associated with a soybean field and coal mine remnant

    USGS Publications Warehouse

    Willand, J.E.; McCravy, K.W.

    2006-01-01

    Diel activities of carabids (Coleoptera: Carabidae) associated with a coal mine remnant and surrounding soybean field were studied in west-central Illinois from June through October 2002. A total of 1,402 carabids, representing 29 species and 17 genera, were collected using pitfall traps. Poecilus chalcites (Say) demonstrated roughly equal diurnal and nocturnal activity in June, but greater diurnal activity thereafter. Pterostichus permundus (Say), Cyclotrachelus seximpressus (LeConte), Amara obesa (Say), and Scarites quadriceps Chaudoir showed significant nocturnal activity. Associations between habitat and diel activity were found for three species: P. chalcites associated with the remnant and edge habitats showed greater diurnal activity than those associated with the soybean field; C. seximpressus was most active diurnally in the remnant, and Harpalus pensylvanicus (DeGeer) showed the greatest nocturnal activity in the remnant and edge habitats. We found significant temporal and habitat-related variation in diel activity among carabid species inhabiting agricultural areas in west-central Illinois.

  16. Evidence of a higher late-Holocene treeline along the Continental Divide in central Colorado

    USGS Publications Warehouse

    Carrara, Paul E.; McGeehin, John

    2015-01-01

    Using a combination of 23 radiocarbon ages and annual ring counts from 18 Rocky Mountain bristlecone pine (Pinus aristata) remnants above the local present-day limits, a period of higher treeline has been determined for two sites near the Continental Divide in central Colorado. The highest remnants were found about 30 m above live bristlecone pines of similar size. The majority of the remnants, consisting of standing snags, large logs, and smaller remains, are highly eroded, such that the innermost annual rings of all but one are missing. The radiocarbon ages obtained from the oldest wood recovered from each remnant indicate that the majority were established above the present-day limit of bristlecone pine from prior to 2700 cal. yr BP to no later than about 1200 cal. yr BP. These radiocarbon ages combined with the annual ring count from the corresponding remnant indicate that the majority of the sampled remnants grew above the present-day limit of bristlecone pine from sometime before 2700 cal. yr BP to about 800 cal. yr BP. Evidence of recent climatic warming is demonstrated at one of the sites by young bristlecone pine saplings growing next to the highest remnants; the saplings were established after AD 1965 and represent the highest advance of treeline in at least 1200 years.

  17. Feasibility of Metabolic Parameter Estimation in Pharmacokinetic Models of Carbon Tetrachloride Exposure in Rats

    EPA Science Inventory

    Carbon tetrachloride (CCl4) is a toxic chemical that was once used in degreasers and detergents, and some remnants of the chemical may be present in the water supply. Physiologically based pharmacokinetic (PBPK) modeling can assist in understanding resulting internal d...

  18. Nonthermal X-Ray Emission from the Shell-Type Supernova Remnant G347.3-0.5

    NASA Technical Reports Server (NTRS)

    Slane, Patrick O.; Gaensler, Bryan M.; Dame, T. M.; Hughes, John P.; Plucinsky, Paul P.; Green, Anne

    2002-01-01

    Recent Advanced Spacecraft for Cosmology Astrophysics (ASCA) observations of G347.3-0.5, a supernova remnant (SNR) discovered in the ROSAT All-Sky Survey, reveal nonthermal emission from a region along the northwestern shell. Here we report on new pointed ASCA observations of G347.3-0.5 that confirm this result for all the bright shell regions and also reveal similar emission, although with slightly different spectral properties, from the remainder of the SNR. Curiously, no thermal X-ray emission is detected anywhere in the remnant. We derive limits on the amount of thermal emitting material present in G347.3-0.5 and present new radio continuum, CO, and infrared results that indicate that the remnant is distant and of moderate age. We show that our observations are broadly consistent with a scenario that has most of the supernova remnant shock wave still within the stellar wind bubble of its progenitor star, while part of it appears to be interacting with denser material. A point source at the center of the remnant has spectral properties similar to those expected for a neutron star and may represent the compact relic of the supernova progenitor.

  19. The Role of Small Woodland Remnants on Ground Dwelling Insect Conservation in Chaco Serrano, Central Argentina

    PubMed Central

    Moreno, María Laura; Fernández, María Guadalupe; Molina, Silvia Itati; Valladares, Graciela

    2013-01-01

    Many terrestrial ecosystems are changing due to extensive land use and habitat fragmentation, posing a major threat to biodiversity. In this study, the effects of patch size, isolation, and edge/interior localization on the ground dwelling insect communities in the Chaco Serrano woodland remnants in central Argentina were examined. Sampling was carried out in December 2003 and March 2004 in nine remnants (0.57 to 1000 hectares) using pitfall traps. In total, 7071 individuals representing 12 orders and 79 families were recorded. The taxonomic composition of these communities was linked to remnant size. Insect abundance increased (as did their richness, albeit marginally) as remnant area decreased, with no significant effects of isolation or edge/interior localization on abundance, richness, or diversity. No differential area effects were observed when abundance and richness of predators, scavengers, and herbivores were compared. Thus, ground insect communities in fragmented Chaco Serrano seem to respond mainly to patch level, rather than to within-patch (edge effects) or landscape (isolation) level variables. These results suggest that small Chaco Serrano remnants, by supporting larger ground-dwelling insect assemblages, may play an important role from a conservation viewpoint. PMID:23902409

  20. The role of small woodland remnants on ground dwelling insect conservation in Chaco Serrano, Central Argentina.

    PubMed

    Moreno, María Laura; Fernández, María Guadalupe; Molina, Silvia Itati; Valladares, Graciela

    2013-01-01

    Many terrestrial ecosystems are changing due to extensive land use and habitat fragmentation, posing a major threat to biodiversity. In this study, the effects of patch size, isolation, and edge/interior localization on the ground dwelling insect communities in the Chaco Serrano woodland remnants in central Argentina were examined. Sampling was carried out in December 2003 and March 2004 in nine remnants (0.57 to 1000 hectares) using pitfall traps. In total, 7071 individuals representing 12 orders and 79 families were recorded. The taxonomic composition of these communities was linked to remnant size. Insect abundance increased (as did their richness, albeit marginally) as remnant area decreased, with no significant effects of isolation or edge/interior localization on abundance, richness, or diversity. No differential area effects were observed when abundance and richness of predators, scavengers, and herbivores were compared. Thus, ground insect communities in fragmented Chaco Serrano seem to respond mainly to patch level, rather than to within-patch (edge effects) or landscape (isolation) level variables. These results suggest that small Chaco Serrano remnants, by supporting larger ground-dwelling insect assemblages, may play an important role from a conservation viewpoint.

  1. Kepler Supernova Remnant: A View from Spitzer Space Telescope

    NASA Image and Video Library

    2004-10-06

    This Spitzer false-color image is a composite of data from the 24 micron channel of Spitzer's multiband imaging photometer (red), and three channels of its infrared array camera: 8 micron (yellow), 5.6 micron (blue), and 4.8 micron (green). Stars are most prominent in the two shorter wavelengths, causing them to show up as turquoise. The supernova remnant is most prominent at 24 microns, arising from dust that has been heated by the supernova shock wave, and re-radiated in the infrared. The 8 micron data shows infrared emission from regions closely associated with the optically emitting regions. These are the densest regions being encountered by the shock wave, and probably arose from condensations in the surrounding material that was lost by the supernova star before it exploded. The composite above (PIA06908, PIA06909, and PIA06910) represent views of Kepler's supernova remnant taken in X-rays, visible light, and infrared radiation. Each top panel in the composite above shows the entire remnant. Each color in the composite represents a different region of the electromagnetic spectrum, from X-rays to infrared light. The X-ray and infrared data cannot be seen with the human eye. Astronomers have color-coded those data so they can be seen in these images. http://photojournal.jpl.nasa.gov/catalog/PIA06910

  2. Intestinal obstruction caused by omphalomesenteric duct remnant: usefulness of laparoscopy.

    PubMed

    Bueno Lledó, J; Serralta Serra, A; Planeéis Roig, M; Dobón Giménez, F; Ibáñez Palacín, F; Rodero Rodero, R

    2003-10-01

    The anomalies related to omphalomesenteric duct remnant constitute an uncommon cause of intestinal obstruction, of which Meckel"s diverticulum and its variants represent the most important clinical presentation. In most cases they are asymptomatic and usually affect young patients. When symptomatic, they usually present episodes of gastrointestinal bleeding or acute abdomen syndromes caused by strangulation of intestinal loops as a result of fibrous intraabdominal remnants or inflammation produced by the diverticulum. In most cases, the unexpected presence of these alterations makes intraoperative diagnosis necessary. Treatment is surgical and consists in exeresis of the diverticulum or the fibrous band causing the clinical picture. We report two cases of persistence of the vitelline duct resolved by laparoscopic approach.

  3. AN X-RAY INVESTIGATION OF THREE SUPERNOVA REMNANTS IN THE LARGE MAGELLANIC CLOUD

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Klimek, Matthew D.; Points, S. D.; Smith, R. C.

    2010-12-20

    We have investigated three supernova remnants (SNRs) in the LMC using multi-wavelength data. These SNRs are generally fainter than the known sample (see Section 4) and may represent a previously missed population. One of our SNRs is the second LMC remnant analyzed which is larger than any Galactic remnant for which a definite size has been established. The analysis of such a large remnant contributes to the understanding of the population of highly evolved SNRs. We have obtained X-ray images and spectra of three of these recently identified SNRs using the XMM-Newton observatory. These data, in conjunction with pre-existing opticalmore » emission-line images and spectra, were used to determine the physical conditions of the optical- and X-ray-emitting gas in the SNRs. We have compared the morphologies of the SNRs in the different wavebands. The physical properties of the warm ionized shell were determined from the H{alpha} surface brightness and the SNR expansion velocity. The X-ray spectra were fit with a thermal plasma model and the physical conditions of the hot gas were derived from the model fits. Finally, we have compared our observations with simulations of SNR evolution.« less

  4. Bumble Bee Fauna of Palouse Prairie: Survey of Native Bee Pollinators in a Fragmented Ecosystem

    PubMed Central

    Hatten, T. D.; Looney, C.; Strange, J. P.; Bosque-Pérez, N. A.

    2013-01-01

    Bumble bees, Bombus Latreille (Hymenoptera: Apidae:), are dominant pollinators in the northern hemisphere, providing important pollination services for commercial crops and innumerable wild plants. Nationwide declines in several bumble bee species and habitat losses in multiple ecosystems have raised concerns about conservation of this important group. In many regions, such as the Palouse Prairie, relatively little is known about bumble bee communities, despite their critical ecosystem functions. Pitfall trap surveys for ground beetles in Palouse prairie remnants conducted in 2002–2003 contained considerable by-catch of bumble bees. The effects of landscape context, remnant features, year, and season on bumble bee community composition were examined. Additionally, bees captured in 2002–2003 were compared with historic records for the region to assess changes in the presence of individual species. Ten species of bumble bee were captured, representing the majority of the species historically known from the region. Few detectable differences in bumble bee abundances were found among remnants. Community composition differed appreciably, however, based on season, landscape context, and elevation, resulting in different bee assemblages between western, low-lying remnants and eastern, higherelevation remnants. The results suggest that conservation of the still species-rich bumble bee fauna should take into account variability among prairie remnants, and further work is required to adequately explain bumble bee habitat associations on the Palouse. PMID:23902138

  5. From the EEL to the EGO: psychoanalysis and the remnants of Freud's early scientific practice.

    PubMed

    Wieser, Martin

    2013-01-01

    While numerous historiographical works have been written to shed light on Freud's early theoretical education in biology, physiology, and medicine and on the influence of that education on psychoanalysis, this paper approaches Freud's basic comprehension of science and methodology by focusing on his early research practice in physiology and neuranatomy. This practice, taking place in the specific context of Ernst Brücke's physiological laboratory in Vienna, was deeply concerned with problems of visuality and the revelation of hidden organic structures by use of proper preparation techniques and optical instruments. The paper explores the connection between such visualizing practices, shaped by a physiological context as they were, and Freud's later convictions of the scientific status of psychoanalysis and the function of its method as means to unveil the concealed structure of the "psychical apparatus". © 2013 Wiley Periodicals, Inc.

  6. Paternity analysis of pollen-mediated gene flow for Fraxinus excelsior L. in a chronically fragmented landscape.

    PubMed

    Bacles, C F E; Ennos, R A

    2008-10-01

    Paternity analysis based on microsatellite marker genotyping was used to infer contemporary genetic connectivity by pollen of three population remnants of the wind-pollinated, wind-dispersed tree Fraxinus excelsior, in a deforested Scottish landscape. By deterministically accounting for genotyping error and comparing a range of assignment methods, individual-based paternity assignments were used to derive population-level estimates of gene flow. Pollen immigration into a 300 ha landscape represents between 43 and 68% of effective pollination, mostly depending on assignment method. Individual male reproductive success is unequal, with 31 of 48 trees fertilizing one seed or more, but only three trees fertilizing more than ten seeds. Spatial analysis suggests a fat-tailed pollen dispersal curve with 85% of detected pollination occurring within 100 m, and 15% spreading between 300 and 1900 m from the source. Identification of immigrating pollen sourced from two neighbouring remnants indicates further effective dispersal at 2900 m. Pollen exchange among remnants is driven by population size rather than geographic distance, with larger remnants acting predominantly as pollen donors, and smaller remnants as pollen recipients. Enhanced wind dispersal of pollen in a barren landscape ensures that the seed produced within the catchment includes genetic material from a wide geographic area. However, gene flow estimates based on analysis of non-dispersed seeds were shown to underestimate realized gene immigration into the remnants by a factor of two suggesting that predictive landscape conservation requires integrated estimates of post-recruitment gene flow occurring via both pollen and seed.

  7. Forensic Analysis of a Contact Lens in a Murder Case.

    PubMed

    Zwerling, Charles S

    2016-03-01

    Contact lenses have had rare relevance in trials and/or investigations. After 5 years of burial, orbital remnants were retrieved from an exhumed body and subsequently identified as a key piece of material evidence in a murder trial. The exhumed case materials were evaluated under laboratory conditions and were determined to be contact lens remnants. Contact lens fracture and burial simulation studies were performed to provide additional corroboration of the physical findings of the exhumed contact lens remnants. This material evidence was instrumental in providing factual proof refuting the defendant's testimony in the murder trial. A brief history of contact lens composition and use is provided for understanding the methods and observational results. This forensic case study represents the first published documentation of a contact lens from an exhumed body being used in a murder investigation and establishes an operational procedure for future forensic contact lens examinations. © 2016 American Academy of Forensic Sciences.

  8. Structure of merger remnants. I - Bulgeless progenitors

    NASA Technical Reports Server (NTRS)

    Hernquist, Lars

    1992-01-01

    The study examines mergers of identical galaxies consisting of self-gravitating disks and halos in the context of the suggestion that such events may form elliptical galaxies. It is shown that the luminous remnants of such mergers do indeed share many common properties with observed ellipticals. Specifically, the end states of the simulations considered rotate slowly in regions of relatively high surface density, having typical values of less than about 0.2 there. Morphologically, the remnants display a variety of structures, including shells and loops comprising loosely bound material and boxy and disky isophotes. The luminous matter is well-fitted by ellipsoidal generalizations of Hernquists's (1990, 1992) model for elliptical galaxies, implying that the surface brightness profiles are essentially de Vaucouleurs-like over a large radial interval. It is proposed that mergers of pure stellar disks do not represent an attractive mechanism for the production of massive elliptical galaxies.

  9. The Sleeping Remnant. Effect of Roux-En-Y Gastric Bypass on Plasma Levels of Gastric Biomarkers in Morbidly Obese Women: A Prospective Longitudinal Study.

    PubMed

    Marchesi, Federico; Tartamella, Francesco; De Sario, Giuseppina; Forlini, Clarissa; Caleffi, Alberta; Riccò, Matteo; Di Mario, Francesco

    2017-07-01

    Morpho-functional modifications of the gastric remnant after Roux-en-Y gastric bypass (RYGB) have not been completely defined, due to its inaccessibility for bioptic mapping. The aim of the study is to evaluate such modifications using Gastropanel®, a non-invasive blood test cross-checking four gastric biomarkers, able to provide a snapshot of mucosa conditions. Twenty-four women undergoing RYGB were prospectively enrolled. Gastropanel® parameters (pepsinogens, Gastrin-17 and immunoglobulins against Helicobacter pylori), biometrical/clinical data were collected preoperatively and at 6-months follow-up. All parameters showed significant reduction (p < 0.05). Pepsinogen I reduction correlated with BMI percent decrease. The exclusion of food transit is responsible for significant drop in gastric output, hardly representing a risk factor in the remnant carcinogenesis, being unexposed to alimentary carcinogenic agents.

  10. Infection of internal umbilical remnant in foals by Clostridium sordellii.

    PubMed

    Ortega, J; Daft, B; Assis, R A; Kinde, H; Anthenill, L; Odani, J; Uzal, F A

    2007-05-01

    Omphalitis and the resulting septicemia contribute to perinatal mortality in several animal species. In foals, the most important causes of omphalitis are Escherichia coli and Streptococcus zooepidemicus. However to date, no information has been published about the role of Clostridium sordellii in these infections. In this paper, we describe 8 cases of perinatal mortality in foals associated with internal umbilical remnant infection by C. sordellii. The foals studied were between 12 and 21 days old at the time of death, and various breeds were represented in the group. Five of the foals were male and 3 were female. The diagnosis was established on the basis of the detection of C. sordellii by 3 methods (culture, fluorescent antibody test, and immunohistochemistry) and on gross and histopathologic findings. All foals had acute peritonitis, and the internal umbilical remnant was thickened by edema, hemorrhage, and fibrosis. A moderate amount of serosanguinous fluid with fibrin strands was present in the pericardial sac and pleural cavity. Histopathologically, the urachus and umbilical arterial walls were thickened by edema and exhibited hemorrhage, fibrin, and leukocytic infiltration. Gram-positive bacterial rods were observed in subepithelial areas of the urachus, the adventicia of umbilical arteries, and interstitium of the internal umbilical remnant. On the basis of these findings, we suggest that C. sordellii should be considered in the differential diagnosis for infections of the internal umbilical remnant in foals.

  11. Radioablative therapy with Iodine-131 on a patient with thyroid cancer and chronic renal failure in hemodialysis first experience in Peru

    NASA Astrophysics Data System (ADS)

    Apaza Veliz, D. G.; Herrera Vera, R. D.; Cardenas Abarca, C. A.; Oporto Gonzales, C. A.; Aguilar Ramírez, C.; Vega Ramírez, J. L.; Urquizo Baldomero, R. M.

    2016-07-01

    The Iodine-131 (I-131) is a radioisotope used as a standard treatment for radioablation of thyroid remnants. Among thyroid cancer patients, the ones undergoing hemodialysis represent a specific group. The dose of I-131 is given orally to these patients, part of it is absorbed by the thyroid remnants and the rest of it, largely not incorporated, is excreted primarily by renal excretion. The use of a high dose of radioactivity in the process, and the inability of excretion, represents a high risk of exposure to the patient, medical staff and hemodialysis equipment. This work describes the procedure applied on the radioablation therapy for thyroid cancer while receiving hemodialysis, minimizing the risks for the patient and the staff involved. This clinical procedure will establish the dosimetric measures, a plan on radiation protection and a treatment protocol for this specific type of patients.

  12. White-nose syndrome survivors do not exhibit frequent arousals associated with Pseudogymnoascus destructans infection.

    PubMed

    Lilley, Thomas Mikael; Johnson, Joseph Samuel; Ruokolainen, Lasse; Rogers, Elisabeth Jeannine; Wilson, Cali Ann; Schell, Spencer Mead; Field, Kenneth Alan; Reeder, DeeAnn Marie

    2016-01-01

    White-nose syndrome (WNS) has devastated bat populations in North America, with millions of bats dead. WNS is associated with physiological changes in hibernating bats, leading to increased arousals from hibernation and premature consumption of fat reserves. However, there is evidence of surviving populations of little brown myotis (Myotis lucifugus) close to where the fungus was first detected nearly ten years ago. We examined the hibernation patterns of a surviving population of little brown myotis and compared them to patterns in populations before the arrival of WNS and populations at the peak of WNS mortality. Despite infection with Pseudogymnoascus destructans, the causative fungal agent, the remnant population displayed less frequent arousals from torpor and lower torpid body temperatures than bats that died from WNS during the peak of mortality. The hibernation patterns of the remnant population resembled pre-WNS patterns with some modifications. These data show that remnant populations of little brown myotis do not experience the increase in periodic arousals from hibernation typified by bats dying from WNS, despite the presence of the fungal pathogen on their skin. These patterns may reflect the use of colder hibernacula microclimates by WNS survivors, and/or may reflect differences in how these bats respond to the disease.

  13. Hepatic venous pressure gradient after portal vein embolization: An accurate predictor of future liver remnant hypertrophy.

    PubMed

    Mohkam, Kayvan; Rode, Agnès; Darnis, Benjamin; Manichon, Anne-Frédérique; Boussel, Loïc; Ducerf, Christian; Merle, Philippe; Lesurtel, Mickaël; Mabrut, Jean-Yves

    2018-05-09

    The impact of portal hemodynamic variations after portal vein embolization on liver regeneration remains unknown. We studied the correlation between the parameters of hepatic venous pressure measured before and after portal vein embolization and future hypertrophy of the liver remnant after portal vein embolization. Between 2014 and 2017, we reviewed patients who were eligible for major hepatectomy and who had portal vein embolization. Patients had undergone simultaneous measurement of portal venous pressure and hepatic venous pressure gradient before and after portal vein embolization by direct puncture of portal vein and inferior vena cava. We assessed these parameters to predict future liver remnant hypertrophy. Twenty-six patients were included. After portal vein embolization, median portal venous pressure (range) increased from 15 (9-24) to 19 (10-27) mm Hg and hepatic venous pressure gradient increased from 5 (0-12) to 8 (0-14) mm Hg. Median future liver remnant volume (range) was 513 (299-933) mL before portal vein embolization versus 724 (499-1279) mL 3 weeks after portal vein embolization, representing a 35% (7.4-83.6) median hypertrophy. Post-portal vein embolization hepatic venous pressure gradient was the most accurate parameter to predict failure of future liver remnant to reach a 30% hypertrophy (c-statistic: 0.882 [95% CI: 0.727-1.000], P < 0.001). A cut-off value of post-portal vein embolization hepatic venous pressure gradient of 8 mm Hg showed a sensitivity of 91% (95% CI: 57%-99%), specificity of 80% (95% CI: 52%-96%), positive predictive value of 77% (95% CI: 46%-95%) and negative predictive value of 92.3% (95% CI: 64.0%-99.8%). On multivariate analysis, post-portal vein embolization hepatic venous pressure gradient and previous chemotherapy were identified as predictors of impaired future liver remnant hypertrophy. Post-portal vein embolization hepatic venous pressure gradient is a simple and reproducible tool which accurately predicts future liver remnant hypertrophy after portal vein embolization and allows early detection of patients who may benefit from more aggressive procedures inducing future liver remnant hypertrophy. (Surgery 2018;143:1-2.). Copyright © 2018 Elsevier Inc. All rights reserved.

  14. The Hebrus Valles Exploration Zone: Access to the Martian Surface and Subsurface

    NASA Astrophysics Data System (ADS)

    Davila, A.; Fairén, A. G.; Rodríguez, A. P.; Schulze-Makuch, D.; Rask, J.; Zavaleta, J.

    2015-10-01

    The Hebrus Valles EZ represents a diverse setting with multiple geological contacts and layers, possible remnant water ice and protected subsurface environments, which could be critical for the establishment of long-term human settlements.

  15. The remnants in Reissner-Nordström-de Sitter quintessence black hole

    NASA Astrophysics Data System (ADS)

    Feng, Zhongwen; Zhang, Li; Zu, Xiaotao

    2014-08-01

    According to the effects of quantum gravity, we investigated the fermion tunneling from the Reissner-Nordström-de Sitter quintessence (RN-dSQ) black hole. The corrected temperature is not only determined by the mass and charge of the black hole, but also depended on the quantum number of the emitted fermion and β, which is a small value representing the effects of quantum gravity. The effects of quantum gravity slowed down the increase of the temperature and led to the remnants of the black hole. We think it is a method to avoid the information loss paradox of black holes.

  16. A high-resolution X-ray image of Puppis A - Inhomogeneities in the interstellar medium

    NASA Technical Reports Server (NTRS)

    Petre, R.; Kriss, G. A.; Winkler, P. F.; Canizares, C. R.

    1982-01-01

    Eleven HRI exposures from the Einstein Observatory are assembled into an 0.1-4 keV image of the Puppis A supernova remnant which displays a complex morphology that may reflect the structure of the shocked interstellar medium. In addition to showing a density gradient of a factor greater than four across the approximately 30 pc diameter of the remnant perpendicular to the galactic plane, a shell of X-ray emission is seen surrounding the northern half of Puppis A, coincident with the radio shell, whose edge brightness profile indicates direct hot plasma heating by the blast wave rather than evaporation from clouds. The interior structure of the supernova remnant suggests inhomogeneities whose sizes range over 0.1-5 pc, but with moderate density contrast. Although isolated clouds of 10-30/cu cm density are responsible for the two brightest X-ray features, they represent only a small fraction of the Puppis A mass.

  17. A Suzaku Study of Ejecta Structure and Origin of Hard X-ray Emission in the Supernova Remnant G156.2+5.7

    NASA Technical Reports Server (NTRS)

    Uchida, Hiroyuki; Tsunemi, Hiroshi; Katsuda, Satoru; Mori, Koji; Petre, Robert; Yamaguchi, Hiroya

    2012-01-01

    We report an X-ray study of the evolved Galactic supernova remnant (SNR) G1S6.2+S.7 based on six pointing observations with Suzaku. The remnant's large extent (100' in diameter) allows us to investigate its radial structure in the northwestern and eastern directions from the apparent center. The X-ray spectra. were well fit with a two-component non-equilibrium ionization model representing the swept-up interstellar medium (ISM) and the metal-rich ejecta. We found prominent central concentrations of Si, S and Fe from the ejecta component; the lighter elements of O, Ne and Mg were distributed more uniformly. The temperature of the ISM component suggests a slow shock (610-960 km/s), hence the remnant's age is estimated to be 7,000-15,000 yr, assuming its distance to be approx. 1.1 kpc. G1S6.2+5.7 has also been thought to emit hard, non-thermal X-rays, despite being considerably older than any other such remnant. In response to a recent discovery of a background cluster of galaxies (2XMM J045637.2+522411), we carefully excluded its contribution, and reexamined the origin of the hard X-ray emission. We found that the residual hard X-ray emission is consistent with the expected level of the cosmic X-ray background. Thus, no robust evidence for the non-thermal emission was obtained from G156.2+5.7. These results are consistent with the picture of an evolved SNR.

  18. Radioablative therapy with Iodine-131 on a patient with thyroid cancer and chronic renal failure in hemodialysis first experience in Peru

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Apaza Veliz, D. G., E-mail: dgav02@gmail.com; Herrera Vera, R. D.; Cardenas Abarca, C. A.

    The Iodine-131 (I-131) is a radioisotope used as a standard treatment for radioablation of thyroid remnants. Among thyroid cancer patients, the ones undergoing hemodialysis represent a specific group. The dose of I-131 is given orally to these patients, part of it is absorbed by the thyroid remnants and the rest of it, largely not incorporated, is excreted primarily by renal excretion. The use of a high dose of radioactivity in the process, and the inability of excretion, represents a high risk of exposure to the patient, medical staff and hemodialysis equipment. This work describes the procedure applied on the radioablationmore » therapy for thyroid cancer while receiving hemodialysis, minimizing the risks for the patient and the staff involved. This clinical procedure will establish the dosimetric measures, a plan on radiation protection and a treatment protocol for this specific type of patients.« less

  19. Targeted DNA Sequencing Reveals Patterns of Local Progression in the Pancreatic Remnant Following Resection of Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas

    PubMed Central

    Pea, Antonio; Yu, Jun; Rezaee, Neda; Luchini, Claudio; He, Jin; Molin, Marco Dal; Griffin, James F.; Fedor, Helen; Fesharakizadeh, Shahriar; Salvia, Roberto; Weiss, Matthew J.; Bassi, Claudio; Cameron, John L.; Zheng, Lei; Scarpa, Aldo; Hruban, Ralph H.; Lennon, Anne Marie; Goggins, Michael

    2016-01-01

    Objective The aim of this study was to characterize patterns of local progression following resection for pancreatic intraductal papillary mucinous neoplasms (IPMN) using targeted next-generation sequencing (NGS). Background Progression of neoplastic disease in the remnant pancreas following resection of IPMN may include development of a new IPMN or ductal adenocarcinoma (PDAC). However, it is not clear whether this progression represents recurrence of the same neoplasm or an independent second neoplasm. Methods Targeted-NGS on genes commonly mutated in IPMN and PDAC was performed on tumors from (1) 13 patients who developed disease progression in the remnant pancreas following resection of IPMN; and (2) 10 patients who underwent a resection for PDAC and had a concomitant IPMN. Mutations in the tumors were compared in order to determine the relationship between neoplasms. In parallel, clinical and pathological characteristics of 260 patients who underwent resection of noninvasive IPMN were reviewed to identify risk factors associated with local progression. Results We identified 3 mechanisms underlying local progression in the remnant pancreas: (1) residual microscopic disease at the resection margin, (2) intraparenchymal spread of neoplastic cells, leading to an anatomically separate but genetically related recurrence, and (3) multifocal disease with genetically distinct lesions. Analysis of the 260 patients with noninvasive IPMNs showed that family history of pancreatic cancer (P = 0.027) and high-grade dysplasia (HGD) (P = 0.003) were independent risk factors for the development of an IPMN with HGD or an invasive carcinoma in the remnant pancreas. Conclusions Using NGS, we identify distinct mechanisms for development of metachronous or synchronous neoplasms in patients with IPMN. Patients with a primary IPMN with HGD or with positive family history are at an increased risk to develop subsequent high-risk neoplasms in the remnant pancreas. PMID:27433916

  20. A Sociologist Looks at Two Schools: The Amherst and Hampshire Experiences.

    ERIC Educational Resources Information Center

    Meister, Joel S.

    1982-01-01

    Hampshire College, representing an innovative response to student discontent, and Amherst College, the exemplar of the liberal arts tradition, are compared. Seen from Amherst, Hampshire's curriculum is trendy, its standards lax, a remnant of California counterculture. From Hampshire, Amherst appears a bastion of cultural elitism and authoritarian…

  1. Saddle Bag Mountain Research Natural Area: guidebook supplement 34.

    Treesearch

    Reid Schuller; Ronald L. Exeter

    2007-01-01

    This guidebook describes the Saddle Bag Mountain Research Natural Area, a 121-ha (300-ac) tract established to represent an old-growth remnant of Pacific silver fir (Abies amabilis) and western hemlock (Tsuga heterophylla) forest in the Oregon Coast Range. Pacific silver fir and noble fir (Abies procera)...

  2. Conifer encroachment in California oak woodlands

    Treesearch

    Matthew I. Cocking; J. Morgan Varner; Eamon A. Engber

    2015-01-01

    California deciduous oak woodlands provide many ecological, cultural, and economic benefits, and often represent unique plant communities that harbor native rare and declining species. Oak woodlands have suffered substantial losses in area and ecological integrity in the post-settlement era due to land conversion and widespread fire exclusion. Remnant oak woodlands in...

  3. The U.S. Geological Survey coal quality (COALQUAL) database version 3.0

    USGS Publications Warehouse

    Palmer, Curtis A.; Oman, Charles L.; Park, Andy J.; Luppens, James A.

    2015-12-21

    Because of database size limits during the development of COALQUAL Version 1.3, many analyses of individual bench samples were merged into whole coal bed averages. The methodology for making these composite intervals was not consistent. Size limits also restricted the amount of georeferencing information and forced removal of qualifier notations such as "less than detection limit" (<) information, which can cause problems when using the data. A review of the original data sheets revealed that COALQUAL Version 2.0 was missing information that was needed for a complete understanding of a coal section. Another important database issue to resolve was the USGS "remnant moisture" problem. Prior to 1998, tests for remnant moisture (as-determined moisture in the sample at the time of analysis) were not performed on any USGS major, minor, or trace element coal analyses. Without the remnant moisture, it is impossible to convert the analyses to a usable basis (as-received, dry, etc.). Based on remnant moisture analyses of hundreds of samples of different ranks (and known residual moisture) reported after 1998, it was possible to develop a method to provide reasonable estimates of remnant moisture for older data to make it more useful in COALQUAL Version 3.0. In addition, COALQUAL Version 3.0 is improved by (1) adding qualifiers, including statistical programming to deal with the qualifiers; (2) clarifying the sample compositing problems; and (3) adding associated samples. Version 3.0 of COALQUAL also represents the first attempt to incorporate data verification by mathematically crosschecking certain analytical parameters. Finally, a new database system was designed and implemented to replace the outdated DOS program used in earlier versions of the database.

  4. Impacto ambiental de los remanentes de supernova

    NASA Astrophysics Data System (ADS)

    Dubner, G. M.

    2015-08-01

    The explosion of a supernovae (SN) represents the sudden injection of about ergs of thermal and mechanical energy in a small region of space, causing the formation of powerful shock waves that propagate through the interstellar medium at speeds of several thousands of km/s. These waves sweep, compress and heat the interstellar material that they encounter, forming the supernova remnants. Their evolution over thousands of years change forever, irreversibly, not only the physical but also the chemical properties of a vast region of space that can span hundreds of parsecs. This contribution briefly analyzes the impact of these explosions, discussing the relevance of some phenomena usually associated with SNe and their remnants in the light of recent theoretical and observational results.

  5. Genetic diversity of wild and hatchery lake trout populations: Relevance for management and restoration in the Great Lakes

    USGS Publications Warehouse

    Page, K.S.; Scribner, K.T.; Burnham-Curtis, M.

    2004-01-01

    The biological diversity of lake trout Salvelinus namaycush in the upper Great Lakes was historically high, consisting of many recognizable morphological types and discrete spawning populations. During the 1950s and 1960s, lake trout populations were extirpated from much of the Great Lakes primarily as a result of overfishing and predation by the parasitic sea lamprey Petromyzon marinus. Investigations of how genetic diversity is partitioned among remnant wild lake trout populations and hatchery broodstocks have been advocated to guide lake trout management and conservation planning. Using microsatellite genetic markers, we estimated measures of genetic diversity and the apportionment of genetic variance among 6 hatchery broodstocks and 10 wild populations representing three morphotypes (lean, humper, and siscowet). Analyses revealed that different hatchery broodstocks and wild populations contributed disproportionally to the total levels of genetic diversity. The genetic affinities of hatchery lake trout reflected the lake basins of origin of the wild source populations. The variance in allele frequency over all sampled extant wild populations was apportioned primarily on the basis of morphotype (??MT = 0.029) and secondarily among geographically dispersed populations within each morphotype (??ST = 0.024). The findings suggest that the genetic divergence reflected in recognized morphotypes and the associated ecological and physiological specialization occurred prior to the partitioning of large proglacial lakes into the Great Lakes or as a consequence of higher contemporary levels of gene flow within than among morphotypes. Information on the relative contributions of different broodstocks to total gene diversity within the regional hatchery program can be used to prioritize the broodstocks to be retained and to guide future stocking strategies. The findings highlight the importance of ecological and phenotypic diversity in Great Lakes fish communities and emphasize that the management of wild remnant lake trout populations and the restoration of extirpated populations should recognize and make greater use of the genetic diversity that still exists.

  6. [Closure of pancreas stump after distal and segmental resection : Suture, stapler, coverage or anastomosis?

    PubMed

    Michalski, C W; Tramelli, P; Büchler, M W; Hackert, T

    2017-01-01

    Postoperative pancreatic fistulas represent the most frequent complication after distal and segmental pancreatectomy and occur with a frequency of up to 50 %. There are many technical variations of pancreatic stump treatment for reduction of fistula rates after distal resection. Most of these techniques have only been analyzed in retrospective studies and the evidence for or against a specific technique is low. Several retrospective trials have been conducted with good results to compare suturing with stapled closure of the remnant and to assess the effect of a vascularized falciform ligament patch in reducing postoperative pancreatic fistula; however, in a recently published randomized trial, which analyzed closure of the remnant with a pancreaticojejunostomy compared to standard closure, these results could not be confirmed. Because stapler resection and closure is the most commonly used technique in laparoscopic distal pancreatectomy, there are a large number of studies which assessed various novel methods of improving stapling. Extended stapler compression time and mesh augmentation of the stapler line can be valid methods to reduce fistula rates. Central pancreatectomy is a relatively rarely used procedure where the right-sided pancreatic remnant is closed in the same fashion as during distal pancreatectomy and the left-sided remnant is connected to the intestines with a pancreaticojejunostomy or pancreaticogastrostomy. In conclusion, postoperative pancreatic fistula rates are still a relevant clinical problem after distal pancreatectomy and further studies on potentially improved novel techniques are required.

  7. Most pseudo-bulges can be formed at later stages of major mergers

    NASA Astrophysics Data System (ADS)

    Sauvaget, T.; Hammer, F.; Puech, M.; Yang, Y. B.; Flores, H.; Rodrigues, M.

    2018-01-01

    Most giant spiral galaxies have pseudo or disc-like bulges that are considered to be the result of purely secular processes. This may challenge the hierarchical scenario predicting about one major merger per massive galaxy (>3 × 1010 M⊙) since the last ∼9 billion years. Here, we verify whether or not the association between pseudo-bulges and secular processes is irrevocable. Using GADGET2 N-body/SPH simulations, we have conducted a systematic study of remnants of major mergers for which progenitors have been selected (1) to follow the gas richness-look back time relationship, and (2) with a representative distribution of orbits and spins in a cosmological frame. Analysing the surface mass density profile of both nearby galaxies and merger remnants with two components, we find that most of them show pseudo-bulges or bar dominated centres. Even if some orbits lead to classical bulges just after the fusion, the contamination by the additional gas that gradually accumulates to the centre and forming stars later on, leads to remnants apparently dominated by pseudo-bulges. We also found that simple smoothed particle hydrodynamics (SPH) simulations should be sufficient to form realistic spiral galaxies as remnants of ancient gas-rich mergers without the need for specifically tuned feedback conditions. We then conclude that pseudo-bulges and bars in spiral galaxies are natural consequences of major mergers when they are realized in a cosmological context, i.e. with gas-rich progenitors as expected when selected in the distant Universe.

  8. Chronically sun-damaged melanomas express low levels of nuclear glutathione-S-transferase-π: an epidemiological and clinicopathological study in Italy.

    PubMed

    Campione, Elena; Medda, Emanuela; Paternò, Evelin J; Diluvio, Laura; Ricozzi, Ilaria; Carboni, Isabella; Costanza, Gaetana; Rossi, Piero; Rapanotti, Cristina; Di Stefani, Alessandro; Chimenti, Sergio; Bianchi, Luca; Orlandi, Augusto

    2015-01-01

    The detoxifying enzyme glutathione-s-transferase pi (GST-π) is present in keratinocytes and melanocytes and exerts a protective role against tumour progression. Melanomas close to melanocytic naevus remnants occur less frequently on sun-exposed areas, whereas solar dermal elastosis, hallmark of chronic sun-damage, characterise melanomas on sun-exposed skin. We evaluated the expression of GST-π in 113 melanomas associated to melanocytic naevus remnants or to solar dermal elastosis, classified according to clinical characteristics, history of sun exposure, histological subtypes and AJCC staging. Chronically sun-damaged melanomas, identified by moderate-severe solar dermal elastosis, showed a lower nuclear GST-π expression and a higher thickness than those related to melanocytic naevus remnants (p < 0.03). Multivariate logistic regression analysis demonstrated that male gender and chronic sun-exposure are independent risk factors significantly associated to melanomas localised on the trunk (OR = 3.36, 95% CI: 1.31-8.65; OR = 5.97, 95% CI: 1.71-20.87). If confirmed on a larger series, lower expression of nuclear GST-π in melanoma cells could represent a possible marker of chronically sun-damaged melanoma pathogenesis.

  9. Restoration practicesin Brazil's Atlantic rainforest.

    Treesearch

    Jorge Correa de Lima Palidon; Maisa dos Santos Guapyassu

    2005-01-01

    The atlantic Rain Forst (Mata Atlantica) extends along the southern coast of Brazil and inland into Argentina and Paraguay. Originally covering 15% of the land area of Brazil, it was a region of an estimated 1.3 million km2 (MMA 2000). Today, remnants of the Atlantic Forest represents about 8% of the original area, or some 94,000 km2...

  10. Early Life on Earth and the Search for Extraterrestrial Biosignatures

    NASA Technical Reports Server (NTRS)

    Oehler, Dorothy Z.; House, Christopher

    2014-01-01

    In the last 2 years, scientists within the ARES Directorate at JSC have applied the technology of Secondary Ion Mass Spectrometry (SIMS) to individual organic structures preserved in Archean (approximately 3 billion years old) sediments on Earth. These organic structures are among the oldest on Earth that may be microfossils - structurally preserved remnants of ancient microbes. The SIMS work was done to determine the microfossils' stable carbon isotopic composition (delta C-13 values). This is the first time that such ancient, potential microfossils have been successfully analyzed for their individual delta C-13 values. The results support the interpretation that these structures are remnants of early life on Earth and that they may represent planktonic organisms that were widely distributed in the Earth's earliest oceans. This study has been accepted for publication in the journal Geology.

  11. Old forests and endangered woodpeckers: old-growth in the Southern Coastal Plain

    Treesearch

    Robert Mitchell; Todd Engstrom; Rebecca Sharitz; Diane De Steven; Kevin Hiers; Robert Cooper; Katherine. Kirkman

    2009-01-01

    Southern old-growth forests are small and rare, but critical in their support of biodiversity. While the remnant old-growth forests contain diversity that is significant regionally and globally, they most likely represent only a portion of the variety that old forests once sustained. High within-habitat diversity and rarity in the landscape magnify the conservation...

  12. Enclosed bark as a pollen trap

    USGS Publications Warehouse

    Adam, D.P.; Ferguson, C.W.; Lamarch, V.C.

    1967-01-01

    Counts were made of pollen in traps formed by enclosed bark in two remnants of bristlecone pine, Pinus aristata Engelm., from the White Mountains of east-central California. The traps, dated by tree-rings at A.D. 350 and 1300 B.C., contained a major complex of pine-sagebrush pollen and traces of other species, representing the equivalent of the present vegetation.

  13. LDL receptor-related protein mediates cell-surface clustering and hepatic sequestration of chylomicron remnants in LDLR-deficient mice.

    PubMed

    Yu, K C; Chen, W; Cooper, A D

    2001-06-01

    It has been proposed that in the liver, chylomicron remnants (lipoproteins carrying dietary lipid) may be sequestered before being internalized by hepatocytes. To study this, chylomicron remnants labeled with a fluorescent dye were perfused into isolated livers of LDL receptor-deficient (LDLR-deficient) mice (Ldlr(-/-)) and examined by confocal microscopy. In contrast to livers from normal mice, there was clustering of the chylomicron remnants on the cell surface in the space of DISSE: These remnant clusters colocalized with clusters of LDLR-related protein (LRP) and could be eliminated by low concentrations of receptor-associated protein, an inhibitor of LRP. When competed with ligands of heparan sulfate proteoglycans (HSPGs), the remnant clusters still appeared but were fewer in number, although syndecans (membrane HSPGs) colocalized with the remnant clusters. This suggests that the clustering of remnants is not dependent on syndecans but that the syndecans may modify the binding of remnants. These results establish that sequestration is a novel process, the clustering of remnants in the space of DISSE: The clustering involves remnants binding to the LRP, and this may be stabilized by binding with syndecans, eventually followed by endocytosis.

  14. On the population of remnant Fanaroff-Riley type II radio galaxies and implications for radio source dynamics

    NASA Astrophysics Data System (ADS)

    Godfrey, L. E. H.; Morganti, R.; Brienza, M.

    2017-10-01

    The purpose of this work is two-fold: (1) to quantify the occurrence of ultrasteep spectrum remnant Fanaroff-Riley type II (FRII) radio galaxies in a 74 MHz flux-limited sample, and (2) perform Monte Carlo simulations of the population of active and remnant FRII radio galaxies to confront models of remnant lobe evolution, and to provide guidance for further investigation of remnant radio galaxies. We find that fewer than 2 per cent of FRII radio galaxies with S74 MHz > 1.5 Jy are candidate ultrasteep spectrum remnants, where we define ultrasteep spectrum as α _74 MHz^1400 MHz > 1.2. Our Monte Carlo simulations demonstrate that models involving Sedov-like expansion in the remnant phase, resulting in rapid adiabatic energy losses, are consistent with this upper limit, and predict the existence of nearly twice as many remnants with normal (not ultrasteep) spectra in the observed frequency range as there are ultrasteep spectrum remnants. This model also predicts an ultrasteep remnant fraction approaching 10 per cent at redshifts z < 0.5. Importantly, this model implies the lobes remain overpressured with respect to the ambient medium well after their active lifetime, in contrast with existing observational evidence that many FRII radio galaxy lobes reach pressure equilibrium with the external medium whilst still in the active phase. The predicted age distribution of remnants is a steeply decreasing function of age. In other words, young remnants are expected to be much more common than old remnants in flux-limited samples. For this reason, incorporating higher frequency data ≳5 GHz will be of great benefit to future studies of the remnant population.

  15. Triglycerides and Heart Disease, Still a Hypothesis?

    PubMed Central

    Goldberg, Ira J.; Eckel, Robert H.; McPherson, Ruth

    2011-01-01

    The purpose of this article is to review the basic and clinical science relating plasma triglycerides and cardiovascular disease. Although many aspects of the basic physiology of triglyceride production, its plasma transport and tissue uptake have been known for several decades, the relationship of plasma triglyceride levels to vascular disease is uncertain. Are triglyceride rich lipoproteins, their influence on HDL and LDL, or the underlying diseases leading to defects in triglyceride metabolism the culprit? Animal models have failed to confirm that anything other than early fatty lesions can be produced by triglyceride-rich lipoproteins. Metabolic products of triglyceride metabolism can be toxic to arterial cells; however, these studies are primarily in vitro. Correlative studies of fasting and postprandial triglycerides and genetic diseases implicate VLDL and their remnants, and chylomicron remnants in atherosclerosis development; but the concomitant alterations in other lipoproteins and other risk factors obscure any conclusions about direct relationships between disease and triglycerides. Genes that regulate triglyceride levels also correlate with vascular disease. Human intervention trials, however, have lacked an appropriately defined population, and have produced outcomes without definitive conclusions. The time is more than ripe for new and creative approaches to understanding the relationship of triglycerides and heart disease. PMID:21527746

  16. Remnant trees affect species composition but not structure of tropical second-growth forest.

    PubMed

    Sandor, Manette E; Chazdon, Robin L

    2014-01-01

    Remnant trees, spared from cutting when tropical forests are cleared for agriculture or grazing, act as nuclei of forest regeneration following field abandonment. Previous studies on remnant trees were primarily conducted in active pasture or old fields abandoned in the previous 2-3 years, and focused on structure and species richness of regenerating forest, but not species composition. Our study is among the first to investigate the effects of remnant trees on neighborhood forest structure, biodiversity, and species composition 20 years post-abandonment. We compared the woody vegetation around individual remnant trees to nearby plots without remnant trees in the same second-growth forests ("control plots"). Forest structure beneath remnant trees did not differ significantly from control plots. Species richness and species diversity were significantly higher around remnant trees. The species composition around remnant trees differed significantly from control plots and more closely resembled the species composition of nearby old-growth forest. The proportion of old-growth specialists and generalists around remnant trees was significantly greater than in control plots. Although previous studies show that remnant trees may initially accelerate secondary forest growth, we found no evidence that they locally affect stem density, basal area, and seedling density at later stages of regrowth. Remnant trees do, however, have a clear effect on the species diversity, composition, and ecological groups of the surrounding woody vegetation, even after 20 years of forest regeneration. To accelerate the return of diversity and old-growth forest species into regrowing forest on abandoned land, landowners should be encouraged to retain remnant trees in agricultural or pastoral fields.

  17. Remnant Trees Affect Species Composition but Not Structure of Tropical Second-Growth Forest

    PubMed Central

    Sandor, Manette E.; Chazdon, Robin L.

    2014-01-01

    Remnant trees, spared from cutting when tropical forests are cleared for agriculture or grazing, act as nuclei of forest regeneration following field abandonment. Previous studies on remnant trees were primarily conducted in active pasture or old fields abandoned in the previous 2–3 years, and focused on structure and species richness of regenerating forest, but not species composition. Our study is among the first to investigate the effects of remnant trees on neighborhood forest structure, biodiversity, and species composition 20 years post-abandonment. We compared the woody vegetation around individual remnant trees to nearby plots without remnant trees in the same second-growth forests (“control plots”). Forest structure beneath remnant trees did not differ significantly from control plots. Species richness and species diversity were significantly higher around remnant trees. The species composition around remnant trees differed significantly from control plots and more closely resembled the species composition of nearby old-growth forest. The proportion of old-growth specialists and generalists around remnant trees was significantly greater than in control plots. Although previous studies show that remnant trees may initially accelerate secondary forest growth, we found no evidence that they locally affect stem density, basal area, and seedling density at later stages of regrowth. Remnant trees do, however, have a clear effect on the species diversity, composition, and ecological groups of the surrounding woody vegetation, even after 20 years of forest regeneration. To accelerate the return of diversity and old-growth forest species into regrowing forest on abandoned land, landowners should be encouraged to retain remnant trees in agricultural or pastoral fields. PMID:24454700

  18. υ-driven winds from the remnant of binary neutron star mergers

    NASA Astrophysics Data System (ADS)

    Perego, A.

    2018-01-01

    We present a 3D hydrodynamic study of the neutrino-driven winds that emerge from the remnant of a neutron star merger, represented by a thick accretion disc orbiting around a massive neutron star. This strong baryonic wind is blown out by neutrino absorption on free baryons inside the disc. It expands within a few tens of ms along the original binary rotation axis. If the central object survives for at least 200ms, the mass ejected in the wind can reach 5% of the initial mass of the accretion disc. Due to the intense neutrino irradiation, matter ejected in the wind increases its electron fraction between 0.3 and 0.4, producing weak r-process nucleosynthesis yields. We predict a distinct UV/optical transient associated with the wind ejecta that peaks from a few hours to a few days after the merger.

  19. Lactational ectopic breast tissue of the vulva: case report and brief historical review.

    PubMed

    Pieh-Holder, Kelly L

    2013-04-01

    Ectopic breast tissue is defined as glands of breast tissue located outside of the normal anatomic breasts. Historically, ectopic breast tissue has been thought to arise from a remnant of the embryonic mammary ridge along the "milk line" or the midaxillary line from the axilla to the groin, including the vulvar region. Extramammary tissue displays the same pathologic and physiologic changes as normal breast tissue and is often discovered in multiparous women as the result of swelling from lactational activity. We present a case report of a gravid patient with lactating vulvar mass and a brief historical perspective of vulvar ectopic breast tissue.

  20. Habitat complexity influences fine scale hydrological processes and the incidence of stormwater runoff in managed urban ecosystems.

    PubMed

    Ossola, Alessandro; Hahs, Amy Kristin; Livesley, Stephen John

    2015-08-15

    Urban ecosystems have traditionally been considered to be pervious features of our cities. Their hydrological properties have largely been investigated at the landscape scale and in comparison with other urban land use types. However, hydrological properties can vary at smaller scales depending upon changes in soil, surface litter and vegetation components. Management practices can directly and indirectly affect each of these components and the overall habitat complexity, ultimately affecting hydrological processes. This study aims to investigate the influence that habitat components and habitat complexity have upon key hydrological processes and the implications for urban habitat management. Using a network of urban parks and remnant nature reserves in Melbourne, Australia, replicate plots representing three types of habitat complexity were established: low-complexity parks, high-complexity parks, and high-complexity remnants. Saturated soil hydraulic conductivity in low-complexity parks was an order of magnitude lower than that measured in the more complex habitat types, due to fewer soil macropores. Conversely, soil water holding capacity in low-complexity parks was significantly higher compared to the two more complex habitat types. Low-complexity parks would generate runoff during modest precipitation events, whereas high-complexity parks and remnants would be able to absorb the vast majority of rainfall events without generating runoff. Litter layers on the soil surface would absorb most of precipitation events in high-complexity parks and high-complexity remnants. To minimize the incidence of stormwater runoff from urban ecosystems, land managers could incrementally increase the complexity of habitat patches, by increasing canopy density and volume, preserving surface litter and maintaining soil macropore structure. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Optical Emission Associated with the Galactic Supernova Remnant G179.0+2.6

    NASA Astrophysics Data System (ADS)

    How, Thomas G.; Fesen, Robert A.; Neustadt, Jack M. M.; Black, Christine S.; Outters, Nicolas

    2018-04-01

    Narrow passband optical images of the large Galactic supernova remnant G179.0+2.6 reveal a faint but nearly complete emission shell dominated by strong [O 3] 4959,5007 Å line emission. The remnant's optical emission, which consists of both diffuse and filamentary features, is brightest along its southern and northeastern limbs. Deep Hα images detect little coincidence emission indicating an unusually high [O 3]/Hα emission ratio for such a large and apparently old remnant. Low-dispersion optical spectra of several regions confirm large [O 3]/Hα line ratios with typical values around 10. The dominance of [O 3] emission for the majority of the remnant's optical filaments suggests shock velocities above 100 km s-1 are present throughout most of the remnant, likely reflecting a relatively low density ambient ISM. The remnant's unusually strong [O 3] emission adds to the remnant's interesting set of properties which include a thick radio emission shell, radial polarization of its radio emission like that typically seen in young supernova remnants, and an unusually slow-rotating gamma-ray pulsar with a characteristic spin-down age ≃ 50 kyr.

  2. Neutron stars in supernova remnants and beyond

    NASA Astrophysics Data System (ADS)

    Gvaramadze, V.

    We propose a new approach for studying the neutron star/supernova remnant associations, based on the idea that the supernova remnants can be products of an off-centered supernova explosion in a preexisting bubble created by the wind of a moving massive star. A cavity supernova explosion of a moving star results in a considerable offset of the neutron star birth-place from the geometrical center of the supernova remnant. Therefore: a) the high transverse velocities inferred for a number of neutron stars through their association with supernova remnants can be reduced; b) the proper motion vector of a neutron star should not necessarily point away from the geometrical center of the associated supernova remnant. Taking into account these two facts allow us to enlarge the circle of possible neutron star/supernova remnant associations, and could significantly affect the results of previous studies of associations. The possibilities of our approach are illustrated with some examples. We also show that the concept of an off-centered cavity supernova explosion could be used to explain the peculiar structures of a number of supernova remnants and for searches for stellar remnants possibly associated with them.

  3. Pancreatic Cancer Arising From the Remnant Pancreas: Is It a Local Recurrence or New Primary Lesion?

    PubMed

    Hashimoto, Daisuke; Chikamoto, Akira; Masuda, Toshiro; Nakagawa, Shigeki; Imai, Katsunori; Yamashita, Yo-Ichi; Reber, Howard A; Baba, Hideo

    2017-10-01

    Local recurrence of pancreatic cancer (PC) can occur in the pancreatic remnant. In addition, new primary PC can develop in the remnant. There are limited data available regarding this so-called remnant PC. The aim of this review was to describe the characteristics and therapeutic strategy regarding remnant PC. A literature search was performed using Medline published in English according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The incidence of remnant PC has been reported to be 3% to 5%. It is difficult to distinguish local recurrence from new primary PC. Genetic diagnosis such as Kirsten rat sarcoma viral oncogene homolog mutation may resolve this problem. For patients with remnant PC, repeated pancreatectomy can be performed. Residual total pancreatectomy is the most common procedure. Recent studies have described the safety of the operation because of recent surgical progress and perioperative care. The patients with remnant PC without distant metastasis have shown good long-term outcomes, especially those who underwent repeated pancreatectomy. Adjuvant chemotherapy may contribute to longer survival. In conclusion, this review found that both local recurrence and new primary PC can develop in the pancreatic remnant. Repeated pancreatectomy for the remnant PC is a feasible procedure and can prolong patient survival.

  4. Imagery and spectroscopy of supernova remnants and H-2 regions

    NASA Technical Reports Server (NTRS)

    Dufour, R. J.

    1984-01-01

    Research activities relating to supernova remnants were summarized. The topics reviewed include: progenitor stars of supernova remnants, UV/optical/radio/X-ray imagery of selected regions in the Cygnus Loop, UV/optical spectroscopy of the Cygnus Loop spur, and extragalactic supernova remnant spectra.

  5. Dead Star Rumbles

    NASA Technical Reports Server (NTRS)

    2005-01-01

    [figure removed for brevity, see original site] Composite of Supernova Remnant Cassiopeia A This Spitzer Space Telescope composite shows the supernova remnant Cassiopeia A (white ball) and surrounding clouds of dust (gray, orange and blue). It consists of two processed images taken one year apart. Dust features that have not changed over time appear gray, while those that have changed are colored blue or orange. Blue represents an earlier time and orange, a later time.

    These observations illustrate that a blast of light from Cassiopeia A is waltzing outward through the dusty skies. This dance, called an 'infrared echo,' began when the remnant erupted about 50 years ago.

    Cassiopeia A is the remnant of a once massive star that died in a violent supernova explosion 325 years ago. It consists of a dead star, called a neutron star, and a surrounding shell of material that was blasted off as the star died. This remnant is located 10,000 light-years away in the northern constellation Cassiopeia.

    An infrared echo is created when a star explodes or erupts, flashing light into surrounding clumps of dust. As the light zips through the dust clumps, it heats them up, causing them to glow successively in infrared, like a chain of Christmas bulbs lighting up one by one. The result is an optical illusion, in which the dust appears to be flying outward at the speed of light. This apparent motion can be seen here by the shift in colored dust clumps.

    Echoes are distinct from supernova shockwaves, which are made up material that is swept up and hurled outward by exploding stars.

    This infrared echo is the largest ever seen, stretching more than 50 light-years away from Cassiopeia A. If viewed from Earth, the entire movie frame would take up the same amount of space as two full moons.

    Hints of an older infrared echo from Cassiopeia A's supernova explosion hundreds of years ago can also be seen.

    The earlier Spitzer image was taken on November 30, 2003, and the later, on December 2, 2004.

  6. High Velocity Gas in the Line of Sight to the Vela SNR

    NASA Technical Reports Server (NTRS)

    Nichols, Joy S.; Slavin, Jonathan D.

    2004-01-01

    One of the best objects for study of the structure, kinematics, and evolutionary status of a middle-aged supernova remnant (SNR) is the VELA SNR, due to its proximity, extensive optical filamentary structure, and an abundance of hot background stars for absorption line research. The VELA remnant is 7.3 degrees in diameter, based on x-ray imagery with ROSAT, with the pulsar nearly centered in the remnant. The western region of the remnant has much lower x-ray surface brightness than the remainder of the remnant and in fact escaped earlier detection with previous instrumentation. The remnant is believed to be about 11,000 years old.

  7. An X-Ray and Radio Study of the Varying Expansion Velocities in Tycho's Supernova Remnant

    NASA Technical Reports Server (NTRS)

    Williams, Brian J.; Chomiuk, Laura; Hewitt, John W.; Blondin, John M.; Borkowski, Kazimierz J.; Ghavamian, Parviz; Petre, Robert; Reynolds, Stephen P.

    2016-01-01

    We present newly obtained X-ray and radio observations of Tycho's supernova remnant using Chandra and the Karl G. Jansky Very Large Array in 2015 and 2013/14, respectively. When combined with earlier epoch observations by these instruments, we now have time baselines for expansion measurements of the remnant of 12-15 year in the X-rays and 30 year in the radio. The remnant's large angular size allows for proper motion measurements at many locations around the periphery of the blast wave. We find, consistent with earlier measurements, a clear gradient in the expansion velocity of the remnant, despite its round shape. The proper motions on the western and southwestern sides of the remnant are about a factor of two higher than those in the east and northeast. We showed in an earlier work that this is related to an offset of the explosion site from the geometric center of the remnant due to a density gradient in the ISM, and using our refined measurements reported here, we find that this offset is approximately 23'' towards the northeast. An explosion center offset in such a circular remnant has implications for searches for progenitor companions in other remnants.

  8. Fire history and age structure analysis in the Sherburne National Wildlife Refuge, Minnesota: establishing reference conditions in a remnant oak savanna woodland

    Treesearch

    Kurt F. Kipfmueller; Tim Hepola

    2009-01-01

    Oak savanna woodlands were once a dominant ecotone in southwestern Minnesota and throughout the upper Midwest. These ecosystems represented a transitional zone between prairie communities to the west that eventually graded into Big Woods forest. Most of the oak savanna landscape of southern Minnesota (and indeed most of the Midwest) were extensively homesteaded and...

  9. Fire history and age structure analysis in the Sherburne National Wildlife Refuge: Establishing reference conditions in a remnant oak savanna woodland

    Treesearch

    Kurt F. Kipfmueller; Tim Hepola

    2007-01-01

    Oak savanna woodlands were once a dominant ecotone throughout the upper Midwest. These ecosystems represented a transitional zone between prairie communities to the west that eventually graded into Big Woods forest. Most of the oak savanna landscapes of most of the Midwest were extensively homesteaded and farmed during the middle 1800s and few intact savanna landscapes...

  10. Risk of venous congestion in live donors of extended right liver graft

    PubMed Central

    Radtke, Arnold; Sgourakis, George; Molmenti, Ernesto P; Beckebaum, Susanne; Cicinnati, Vito R; Schmidt, Hartmut; Peitgen, Heinz-Otto; Broelsch, Christoph E; Malagó, Massimo; Schroeder, Tobias

    2015-01-01

    AIM: To investigate middle hepatic vein (MHV) management in adult living donor liver transplantation and safer remnant volumes (RV). METHODS: There were 59 grafts with and 12 grafts without MHV (including 4 with MHV-5/8 reconstructions). All donors underwent our five-step protocol evaluation containing a preoperative protocol liver biopsy Congestive vs non-congestive RV, remnant-volume-body-weight ratios (RVBWR) and postoperative outcomes were evaluated in 71 right graft living donors. Dominant vs non-dominant MHV anatomy in total liver volume (d-MHV/TLV vs nd-MHV/TLV) was constellated with large/small congestion volumes (CV-index). Small for size (SFS) and non-SFS remnant considerations were based on standard cut-off- RVBWR and RV/TLV. Non-congestive RVBWR was based on non-congestive RV. RESULTS: MHV and non-MHV remnants showed no significant differences in RV, RV/TLV, RVBWR, total bilirubin, or INR. SFS-remnants with RV/TLV < 30% and non-SFS-remnants with RV/TLV ≥ 30% showed no significant differences either. RV and RVBWR for non-MHV (n = 59) and MHV-containing (n = 12) remnants were 550 ± 95 mL and 0.79 ± 0.1 mL vs 568 ± 97 mL and 0.79 ± 0.13, respectively (P = 0.423 and P = 0.919. Mean left RV/TLV was 35.8% ± 3.9%. Non-MHV (n = 59) and MHV-containing (n = 12) remnants (34.1% ± 3% vs 36% ± 4% respectively, P = 0.148. Eight SFS-remnants with RVBWR < 0.65 had a significantly smaller RV/TLV than 63 non-SFS-remnants with RVBWR ≥ 0.65 [SFS: RV/TLV 32.4% (range: 28%-35.7%) vs non-SFS: RV/TLV 36.2% (range: 26.1%-45.5%), P < 0.009. Six SFS-remnants with RV/TLV < 30% had significantly smaller RVBWR than 65 non-SFS-remnants with RV/TLV ≥ 30% (0.65 (range: 0.6-0.7) vs 0.8 (range: 0.6-1.27), P < 0.01. Two (2.8%) donors developed reversible liver failure. RVBWR and RV/TLV were concordant in 25%-33% of SFS and in 92%-94% of non-SFS remnants. MHV management options including complete MHV vs MHV-4A selective retention were necessary in n = 12 vs n = 2 remnants based on particularly risky congestive and non-congestive volume constellations. CONCLUSION: MHV procurement should consider individual remnant congestive- and non-congestive volume components and anatomy characteristics, RVBWR-RV/TLV constellation enables the identification of marginally small remnants. PMID:26019467

  11. Tectonic evolution of the Caribbean and northwestern South America: The case for accretion of two Late Cretaceous oceanic plateaus

    NASA Astrophysics Data System (ADS)

    Kerr, Andrew C.; Tarney, John

    2005-04-01

    It is widely accepted that the thickened oceanic crust of the Caribbean plate, its basaltic accreted margins, and accreted mafic terranes in northwestern South America represent the remnants of a single ca. 90 Ma oceanic plateau. We review geologic, geochemical, and paleomagnetic evidence that suggests that the Caribbean-Colombian oceanic plateau in fact represents the remnants of two different oceanic plateaus, both dated as ca. 90 Ma. The first of these plateaus, the Caribbean Plateau, formed ca. 90 Ma in the vicinity of the present-day Galapagos hotspot. Northeastward movement of the Farallon plate meant that this plateau collided with the proto Caribbean arc and northwestern South America <10 m.y. after the plateau's main phase of formation. Paleomagnetic evidence suggests that the second of these plateaus, the Gorgona Plateau, formed at 26° 30°S, possibly at the site of the present-day Sala y Gomez hotspot. Over the next ˜45 m.y., this plateau was carried progressively northeastward on the Farallon plate and collided in the middle Eocene with the proto Andean subduction zone in northwestern South America. The recognition of a second ca. 90 Ma Pacific oceanic plateau strengthens the link between plateau formation and global oceanic anoxic events.

  12. Does remnant gastric cancer really differ from primary gastric cancer? A systematic review of the literature by the Task Force of Japanese Gastric Cancer Association.

    PubMed

    Shimada, Hideaki; Fukagawa, Takeo; Haga, Yoshio; Oba, Koji

    2016-04-01

    Remnant gastric cancer, most frequently defined as cancer detected in the remnant stomach after distal gastrectomy for benign disease and those cases after surgery of gastric cancer at least 5 years after the primary surgery, is often reported as a tumor with poor prognosis. The Task Force of Japanese Gastric Cancer Association for Research Promotion evaluated the clinical impact of remnant gastric cancer by systematically reviewing publications focusing on molecular carcinogenesis, lymph node status, patient survival, and surgical complications. A systematic literature search was performed using PubMed/MEDLINE with the keywords "remnant," "stomach," and "cancer," revealing 1154 relevant reports published up to the end of December 2014. The mean interval between the initial surgery and the diagnosis of remnant gastric cancer ranged from 10 to 30 years. The incidence of lymph node metastases at the splenic hilum for remnant gastric cancer is not significantly higher than that for primary proximal gastric cancer. Lymph node involvement in the jejunal mesentery is a phenomenon peculiar to remnant gastric cancer after Billroth II reconstruction. Prognosis and postoperative morbidity and mortality rates seem to be comparable to those for primary proximal gastric cancer. The crude 5-year mortality for remnant gastric cancer was 1.08 times higher than that for primary proximal gastric cancer, but this difference was not statistically significant. In conclusion, although no prospective cohort study has yet evaluated the clinical significance of remnant gastric cancer, our literature review suggests that remnant gastric cancer does not adversely affect patient prognosis and postoperative course.

  13. Einstein Observations of Galactic supernova remnants

    NASA Technical Reports Server (NTRS)

    Seward, Frederick D.

    1990-01-01

    This paper summarizes the observations of Galactic supernova remnants with the imaging detectors of the Einstein Observatory. X-ray surface brightness contours of 47 remnants are shown together with gray-scale pictures. Count rates for these remnants have been derived and are listed for the HRI, IPC, and MPC detectors.

  14. A Comparative Study of Clinical Outcomes and Second-Look Arthroscopic Findings between Remnant-Preserving Tibialis Tendon Allograft and Hamstring Tendon Autograft in Anterior Cruciate Ligament Reconstruction: Matched-Pair Design.

    PubMed

    Kim, You Keun; Ahn, Jong Hyun; Yoo, Jae Doo

    2017-12-01

    This study aimed to compare stability, functional outcome, and second-look arthroscopic findings after anterior cruciate ligament reconstruction between remnant-preserving tibialis tendon allograft and remnant-sacrificing hamstring tendon autograft. We matched two groups (remnant-preserving tibialis tendon allograft group and hamstring tendon autograft group) in terms of demographic characteristics, associated injury, and knee characteristics. Each group consisted of 25 patients. Operation time was longer in the remnant-preserving tibialis tendon allograft group, but there was no significant intergroup difference in stability, clinical outcome, and second-look arthroscopic findings. When an autograft is not feasible in anterior cruciate ligament reconstruction, the remnant-preserving technique can produce comparable results in terms of restoration of function, stability of the knee, and degree of synovium coverage at second-look arthroscopy compared to remnant-sacrificing hamstring autograft.

  15. 16 CFR 303.13 - Sale of remnants and products made of remnants.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ACTS OF CONGRESS RULES AND REGULATIONS UNDER THE TEXTILE FIBER PRODUCTS IDENTIFICATION ACT § 303.13... information as “remnants of undetermined fiber content.” (2) Where such remnants of fabrics are displayed for... conjunction with such display, stating with respect to required fiber content disclosure that the goods are...

  16. Importance of riparian remnants for frog species diversity in a highly fragmented rainforest.

    PubMed

    Rodríguez-Mendoza, Clara; Pineda, Eduardo

    2010-12-23

    Tropical forests undergo continuous transformation to other land uses, resulting in landscapes typified by forest fragments surrounded by anthropogenic habitats. Small forest fragments, specifically strip-shaped remnants flanking streams (referred to as riparian remnants), can be particularly important for the maintenance and conservation of biodiversity within highly fragmented forests. We compared frog species diversity between riparian remnants, other forest fragments and cattle pastures in a tropical landscape in Los Tuxtlas, Mexico. We found similar species richness in the three habitats studied and a similar assemblage structure between riparian remnants and forest fragments, although species composition differed by 50 per cent. Frog abundance was halved in riparian remnants compared with forest fragments, but was twice that found in pastures. Our results suggest that riparian remnants play an important role in maintaining a portion of frog species diversity in a highly fragmented forest, particularly during environmentally stressful (hot and dry) periods. In this regard, however, the role of riparian remnants is complementary, rather than substitutive, with respect to the function of other forest fragments within the fragmented forest.

  17. A 3D View of a Supernova Remnant

    NASA Astrophysics Data System (ADS)

    Kohler, Susanna

    2017-06-01

    The outlined regions mark the 57 knots in Tycho selected by the authors for velocity measurements. Magenta regions have redshifted line-of-sight velocities (moving away from us); cyan regions have blueshifted light-of-sight velocities (moving toward us). [Williams et al. 2017]The Tycho supernova remnant was first observed in the year 1572. Nearly 450 years later, astronomers have now used X-ray observations of Tycho to build the first-ever 3D map of a Type Ia supernova remnant.Signs of ExplosionsSupernova remnants are spectacular structures formed by the ejecta of stellar explosions as they expand outwards into the surrounding interstellar medium.One peculiarity of these remnants is that they often exhibit asymmetries in their appearance and motion. Is this because the ejecta are expanding into a nonuniform interstellar medium? Or was the explosion itself asymmetric? The best way we can explore this question is with detailed observations of the remnants.Histograms of the velocity in distribution of the knots in the X (green), Y (blue) and Z (red) directions (+Z is away from the observer). They show no evidence for asymmetric expansion of the knots. [Williams et al. 2017]Enter TychoTo this end, a team of scientists led by Brian Williams (Space Telescope Science Institute and NASA Goddard SFC) has worked to map out the 3D velocities of the ejecta in the Tycho supernova remnant. Tycho is a Type Ia supernova thought to be caused by the thermonuclear explosion of a white dwarf in a binary system that was destabilized by mass transfer from its companion.After 450 years of expansion, the remnant now has the morphological appearance of a roughly circular cloud of clumpy ejecta. The forward shock wave from the supernova, however, is known to have twice the velocity on one side of the shell as on the other.To better understand this asymmetry, Williams and collaborators selected a total of 57 knots in Tychos ejecta, spread out around the remnant. They then used 12 years of Chandra X-ray observations to measure both the knots proper motion in the plane of the sky and their line-of-sight velocity. These two measurements were then combined to build a full 3D map of the motion of the ejecta.3D hydrodynamical simulations of Tycho, stopped at the current epoch. These show that both initially smooth (top) and initially clumpy (bottom) ejecta models are consistent with the current observations of the morphology and dynamics of Tychos ejecta. [Adapted from Williams et al. 2017]Symmetry and ClumpsWilliams and collaborators found that the knots have total velocities that range from 2400 to 6600 km/s. Unlike the forward shock of the supernova, Tychos ejecta display no asymmetries in their motion which suggests that the explosion itself was symmetric. The more likely explanation is a density gradient in the interstellar medium, which could slow the shock wave on one side of the remnant without yet affecting the motion of the clumps of ejecta.As a final exploration, the authors attempt to address the origin of Tychos clumpiness. The fact that some of Tychos ejecta knots precede its outer edge has raised the question of whether the ejecta started out clumpy, or if they began smooth and only clumped during expansion. Williams and collaborators matched the morphological and dynamical data to simulations, demonstrating that neither scenario can be ruled out at this time.This first 3D map of a Type Ia supernova represents an important step in our ability to understand these stellar explosions. The authors suggest that well be able to expand on this map in the future with additional observations from Chandra, as well as with new data from future X-ray observatories that will be able to detect fainter emission.CitationBrian J. Williams et al 2017 ApJ 842 28. doi:10.3847/1538-4357/aa7384

  18. Predicted TeV Gamma-ray Spectra and Images of Shell Supernova Remnants

    NASA Astrophysics Data System (ADS)

    Reynolds, S. P.

    1999-04-01

    One supernova remnant, SN 1006, is now known to produce synchrotron X-rays (Koyama et al., 1995, Nature, 378, 255), requiring 100 TeV electrons. SN 1006 has also been seen in TeV gamma rays (Tanimori et al., 1998, ApJ, 497, L25), almost certainly due to cosmic-microwave-background photons being upscattered by those same electrons. Other young supernova remnants should also produce high-energy electrons, even if their X-ray synchrotron emission is swamped by conventional thermal X-ray emission. Upper limits to the maximum energy of shock-accelerated electrons can be found for those remnants by requiring that their synchrotron spectrum steepen enough to fall below observed thermal X-rays (Reynolds and Keohane 1999, ApJ, submitted). For those upper-limit spectra, I present predicted TeV inverse-Compton spectra and images for assumed values of the mean remnant magnetic field. Ground-based TeV gamma-ray observations of remnants may be able to put even more severe limits on the presence of highly energetic electrons in remnants, raising problems for conventional theories of galactic cosmic-ray production in supernova remnants. Detections will immediately confirm that SN 1006 is not alone, and will give mean remnant magnetic field strengths.

  19. A distance estimate to the Cygnus Loop based on the distances to two stars located within the remnant

    NASA Astrophysics Data System (ADS)

    Fesen, Robert A.; Neustadt, Jack M. M.; Black, Christine S.; Milisavljevic, Dan

    2018-04-01

    Underlying nearly every quantitative discussion of the Cygnus Loop supernova remnant is uncertainty about its distance. Here, we present optical images and spectra of nebulosities around two stars whose mass-loss material appears to have interacted with the remnant's expanding shock front and thus can be used to estimate the Cygnus Loop's distance. Narrow passband images reveal a small emission-line nebula surrounding an M4 red giant near the remnant's eastern nebula NGC 6992. Optical spectra of the nebula show it to be shock-heated with significantly higher electron densities than seen in the remnant's filaments. This along with a bow-shaped morphology suggests it is likely red giant mass-loss material shocked and accelerated by passage of the Cygnus Loop's blast wave. We also identify a B7 V star located along the remnant's northwestern limb, which also appears to have interacted with the remnant's shock wave. It lies within a small arc of nebulosity in an unusually complex region of curved and distorted filaments along the remnant's northern shock front suggestive of a localized disturbance of the shock front due to the B star's stellar winds. Based on the assumption that these two stars lie inside the remnant, combined with an estimated distance to a molecular cloud situated along the remnant's western limb, we propose a distance to the Cygnus Loop of 1.0 ± 0.2 kpc. Although larger than several recent estimates of 500-800 pc, a distance ≃1 kpc helps resolve difficulties with the remnant's postshock cosmic ray and gas pressure ratio and estimated supernova explosion energy.

  20. Chylomicron remnants and nonesterified fatty acids differ in their ability to inhibit genes involved in lipogenesis in rats.

    PubMed

    Kohan, Alison B; Qing, Yang; Cyphert, Holly A; Tso, Patrick; Salati, Lisa M

    2011-02-01

    Primary hepatocytes treated with nonesterified PUFA have been used as a model for analyzing the inhibitory effects of dietary polyunsaturated fats on lipogenic gene expression. Although nonesterified fatty acids play an important signaling role in starvation, they do not completely recapitulate the mechanism of dietary fat presentation to the liver, which is delivered via chylomicron remnants. To test the effect of remnant TG on lipogenic enzyme expression, chylomicron remnants were generated from the lymph of rats intubated with either safflower oil or lard. The remnants were added to the medium of primary rat hepatocytes in culture and the accumulation of mRNA for genes involved in carbohydrate and lipid metabolism was measured. Both PUFA-enriched remnants and nonesterified PUFA inhibited the expression and maturation of sterol response element binding protein-1c (SREBP-1c) and the expression of lipogenic genes regulated by this transcription factor. These remnants also inhibited the expression of glucose-6-phosphate dehydrogenase (G6PD), a gene regulated at post-transcriptional steps. In contrast, PUFA-enriched remnants did not inhibit the accumulation of mRNA for malic enzyme, glucokinase, and L-pyruvate kinase, whereas nonesterified fatty acids caused a decrease in these mRNA. These genes are regulated independently of SREBP-1c. SFA-enriched remnants did not inhibit lipogenic gene expression, which is consistent with a lack of inhibition of lipogenesis by dietary saturated fats. Thus, the inhibitory action of dietary polyunsaturated fats on lipogenesis involves a direct action of chylomicron remnants on the liver.

  1. Influence of the Roof Movement Control Method on the Stability of Remnant

    NASA Astrophysics Data System (ADS)

    Adach-Pawelus, Karolina

    2017-12-01

    In the underground mines, there are geological and mining situations that necessitate leaving behind remnants in the mining field. Remnants, in the form of small, irregular parcels, are usually separated in the case of: significant problems with maintaining roof stability, high rockburst hazard, the occurrence of complex geological conditions and for random reasons (ore remnants), as well as for economic reasons (undisturbed rock remnants). Remnants left in the mining field become sites of high stress values concentration and may affect the rock in their vicinity. The values of stress inside the remnant and its vicinity, as well as the stability of the remnant, largely depend on the roof movement control method used in the mining field. The article presents the results of the numerical analysis of the influence of roof movement control method on remnant stability and the geomechanical situation in the mining field. The numerical analysis was conducted for the geological and mining conditions characteristic of Polish underground copper mines owned by KGHM Polska Miedz S.A. Numerical simulations were performed in a plane strain state by means of Phase 2 v. 8.0 software, based on the finite element method. The behaviour of remnant and rock mass in its vicinity was simulated in the subsequent steps of the room and pillar mining system for three types of roof movement control method: roof deflection, dry backfill and hydraulic backfill. The parameters of the rock mass accepted for numerical modelling were calculated by means of RocLab software on the basis of the Hoek-Brown classification. The Mohr-Coulomb strength criterion was applied.

  2. G65.2+5.7: A Thermal Composite Supernova Remnant with a Cool Shell

    NASA Technical Reports Server (NTRS)

    Shelton, R. L.; Kuntz, K. D.; Petre, R.

    2004-01-01

    This paper presents archival ROSAT PSPC observations of the G65.2+5.7 supernova remnant (also known as G65.3+5.7). Little material obscures this remnant and so it was well observed, even at the softest end of ROSATs bandpass (approx. 0.11 to 0.28 keV). These soft X-ray images reveal the remnant s centrally-filled morphology which, in combination with existing radio frequency observations, places G65.2+5.7 in the thermal composite (mixed morphology) class of supernova remnants. Not only might G65.2+5.7 be the oldest known thermal composite supernova remnant, but owing to its optically revealed cool, dense shell, this remnant supports the proposal that thermal composite supernova remnants lack X-ray bright shells because they have evolved beyond the adiabatic phase. These observations also reveal a slightly extended point source centered on RA = l9(sup h) 36(sup m) 46(sup s). dec = 30 deg.40 min.07 sec.and extending 6.5 arc min in radius in the band 67 map. The source of this emission has yet to be discovered, as there is no known pulsar at this location.

  3. Effect of Hashimoto thyroiditis on low-dose radioactive-iodine remnant ablation.

    PubMed

    Kwon, Hyungju; Choi, June Young; Moon, Jae Hoon; Park, Hyo Jin; Lee, Won Woo; Lee, Kyu Eun

    2016-04-01

    Radioactive-iodine remnant ablation is an integral part of the papillary thyroid carcinoma (PTC) treatment. Although a minimum dose is usually recommended, there is controversy as to whether the low-dose (1100 MBq) radioactive-iodine remnant ablation is adequate for selected patients. A retrospective cohort study was conducted on 691 patients. Patients with no remnant thyroid on the follow-up whole body scan and low stimulated thyroglobulin (sTg) level (<2.0 ng/mL) were deemed as successful treatment cases. Initial low-dose radioactive-iodine remnant ablation was successful in 431 patients (62.3%). Multivariate analysis demonstrated a negative correlation between successful radioactive-iodine remnant ablation and coexisting Hashimoto thyroiditis based on histopathology diagnosis (odds ratio [OR] = 3.23; p < .001) as well as elevated preablation sTg (OR = 1.24; p < .001). Our data suggest that coexisting Hashimoto thyroiditis and elevated sTg are negative predictive factors for successful low-dose radioactive-iodine remnant ablation treatment. An appropriate risk-adjusted approach may improve the efficacy of radioactive-iodine remnant ablation treatment. © 2015 Wiley Periodicals, Inc. Head Neck 38: E730-E735, 2016. © 2015 Wiley Periodicals, Inc.

  4. The orchid-bee faunas (Hymenoptera: Apidae) of "Reserva Ecológica Michelin", "RPPN Serra Bonita" and one Atlantic Forest remnant in the state of Bahia, Brazil, with new geographic records.

    PubMed

    Nemésio, A

    2014-02-01

    The orchid bee faunas of two private natural preserves, 'Reserva Particular do Patrimônio Natural da Serra Bonita' (RSB) and 'Reserva Ecológica Michelin' (REM), and a forest fragment inside the campus of the 'Universidade Estadual de Santa Cruz', were surveyed for the first time. All three areas constitute Atlantic Forest remnants in the southern portion of the state of Bahia, Brazil. A total of 1,782 males belonging to 32 species were actively collected with insect nets during 90 hours of field work from November, 2009, to January, 2012. Euglossa cyanochlora Moure, 1996-one of the rarest orchid bee species-was found at RSB and REM, the latter representing the northernmost record for this species. Euglossa cognata, Moure, 1970 was found at RSB, the northernmost record for this species in the Atlantic Forest and the only recent record for this species at the northern border of Jequitinhonha river.

  5. Pulsar Wind Nebulae, Space Velocities and Supernova Remnant

    NASA Technical Reports Server (NTRS)

    2005-01-01

    The original proposal for this LTSA grant was for X-ray studies of pulsars, and especially pulsar wind nebulae and what they could tell us about pulsar properties, especially their space velocities. By any metric, this program has been very successful. No fewer than 14 papers on directly related topics (and several dozen more on related topics) have been published in refereed journals with the PI as lead or co-author, all observational results that have had significant impact on the field. These include the first X-ray detection of the "Duck" pulsar, a clear demonstration that estimated pulsar ages can be off by over an order of magnitude (via observations of the young supernova remnant G11.2-0.3) and the detection of the first pulsar wind nebula around a millisecond pulsar. These publications have also resulted in 4 press releases. Moreover, they also represent the thesis work of two PhD students at MIT (Froney Crawford and Mike Pivovaroff) and one postdoctoral fellow, Bryan Gaensler, now Assistant Professor at Harvard.

  6. G29.7-0.3: another supernova remnant with an identity crisis

    NASA Technical Reports Server (NTRS)

    Becker, R. H.; Helfand, D. J.; Szymkowiak, A. E.

    1983-01-01

    New radio and X-ray observations of the galactic supernova remnant G29.7-0.3 show that it is composed of two spectrally distinct components: a steep-spectrum, incomplete shell 3 arcmin in extent enclosing a flat-spectrum, X-ray emitting region 30 arcsec across. Thus, G29.7-0.3 joins the ranks of supernova remnants which exhibit a combination of Crab-like and shell remnant attributes. The Crab-like core has the highest ratio of X-ray radio luminosity of all the Crab-like remnants observed to date, suggesting that it is an extremely young object.

  7. Neutron Stars in Supernova Remnants and Beyond

    NASA Astrophysics Data System (ADS)

    Gvaramadze, V. V.

    We discuss a concept of off-centred cavity supernova explosion as applied to neutron star/supernova remnant associations and show how this concept could be used to preclude the anti-humane decapitating the Duck (G5.4-1.2 + G5.27-0.9) and dismembering the Swan (Cygnus Loop), as well as to search for a stellar remnant associated with the supernova remnant RCW86.

  8. Supernova Remnant Kes 17: An Efficient Cosmic Ray Accelerator inside a Molecular Cloud

    NASA Astrophysics Data System (ADS)

    Gelfand, Joseph; Slane, Patrick; Hughes, John; Temim, Tea; Castro, Daniel; Rakowski, Cara

    Supernova remnant are believed to be the dominant source of cosmic rays protons below the "knee" in the energy spectrum. However, relatively few supernova remnants have been identified as efficient producers of cosmic ray protons. In this talk, I will present evidence that the production of cosmic ray protons is required to explain the broadband non-thermal spectrum of supernova remnant Kes 17 (SNR G304.6+0.1). Evidence for efficient cosmic ray acceleration in Kes 17 supports recent theoretical work concluding that the strong magnetic field, turbulence, and clumpy nature of molecular clouds enhance cosmic ray production in supernova remnants. While additional observations are needed to confirm this interpretation, further study of Kes 17 and similar sources are important for understanding how cosmic rays are accelerated in supernova remnants.

  9. AN X-RAY AND RADIO STUDY OF THE VARYING EXPANSION VELOCITIES IN TYCHO’S SUPERNOVA REMNANT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Williams, Brian J.; Chomiuk, Laura; Hewitt, John W.

    2016-06-01

    We present newly obtained X-ray and radio observations of Tycho’s supernova remnant using Chandra and the Karl G. Jansky Very Large Array in 2015 and 2013/14, respectively. When combined with earlier epoch observations by these instruments, we now have time baselines for expansion measurements of the remnant of 12–15 years in the X-rays and 30 years in the radio. The remnant’s large angular size allows for proper motion measurements at many locations around the periphery of the blast wave. Consistent with earlier measurements, we find a clear gradient in the expansion velocity of the remnant, despite its round shape. Themore » proper motions on the western and southwestern sides of the remnant are about a factor of two higher than those in the east and northeast. We showed in an earlier work that this is related to an offset of the explosion site from the geometric center of the remnant due to a density gradient in the ISM, and using our refined measurements reported here, we find that this offset is ∼23″ toward the northeast. An explosion center offset in such a circular remnant has implications for searches for progenitor companions in other remnants.« less

  10. How large is large enough for insects? Forest fragmentation effects at three spatial scales

    NASA Astrophysics Data System (ADS)

    Ribas, C. R.; Sobrinho, T. G.; Schoereder, J. H.; Sperber, C. F.; Lopes-Andrade, C.; Soares, S. M.

    2005-02-01

    Several mechanisms may lead to species loss in fragmented habitats, such as edge and shape effects, loss of habitat and heterogeneity. Ants and crickets were sampled in 18 forest remnants in south-eastern Brazil, to test whether a group of small remnants maintains the same insect species richness as similar sized large remnants, at three spatial scales. We tested hypotheses about alpha and gamma diversity to explain the results. Groups of remnants conserve as many species of ants as a single one. Crickets, however, showed a scale-dependent pattern: at small scales there was no significant or important difference between groups of remnants and a single one, while at the larger scale the group of remnants maintained more species. Alpha diversity (local species richness) was similar in a group of remnants and in a single one, at the three spatial scales, both for ants and crickets. Gamma diversity, however, varied both with taxa (ants and crickets) and spatial scale, which may be linked to insect mobility, remnant isolation, and habitat heterogeneity. Biological characteristics of the organisms involved have to be considered when studying fragmentation effects, as well as spatial scale at which it operates. Mobility of the organisms influences fragmentation effects, and consequently conservation strategies.

  11. Structural determination of glucosylceramides in the distillation remnants of shochu, the Japanese traditional liquor, and its production by Aspergillus kawachii.

    PubMed

    Hirata, Miyo; Tsuge, Keisuke; Jayakody, Lahiru N; Urano, Yoshitaka; Sawada, Kazutaka; Inaba, Shigeki; Nagao, Koji; Kitagaki, Hiroshi

    2012-11-21

    Shochu is traditional Japanese liquor produced from various crops and fungi Aspergillus kawachi or A. awamorii . The amount of unutilized shochu distillation remnants is increasing because of the recent prohibition of ocean dumping of these remnants. In this Article, we first describe the structures of glucosylceramides contained in shochu distillation remnants by fragment ion analysis using ESI-tandem mass spectrometry. Shochu distillation remnant produced from barley contained glucosylceramides d18:2/C16:0h, d18:2/C20:0h, d19:2/C18:1h, and d18:2/C18:0h. Koji (barley fermented with A. kawachii) contained the same glucosylceramides. Shochu distillation remnants produced from rice contained glucosylceramides d18:2/C18:0h and d19:2/C18:1h. The culture broth of A. kawachii contained glucosylceramides d19:2/C18:1h and d19:2/C18:0h. These results indicate that the glucosylceramides contained in crops and those produced by A. kawachii transfer through the processes of fermentation with yeast and distillation to the shochu distillation remnant. This information will enable utilization of shochu distillation remnants and koji as novel sources of sphingolipids.

  12. State of the interface between conservation and physiology: a bibliometric analysis.

    PubMed

    Lennox, Robert; Cooke, Steven J

    2014-01-01

    Contemporary conservation science benefits from the perspectives of a variety of different disciplines, including a recent synergy with physiology, an interface known as 'conservation physiology'. To evaluate the degree of interaction between conservation and animal/plant physiology, we conducted three bibliometric analyses. We first pursued the use of the term 'conservation physiology' since its first definition in 2006 to determine how frequently it has been used and in which publications. Secondly, we evaluated the occurrence of conservation terms in animal and plant physiology journals, physiological terms in conservation journals, and a combination of terms in ecology journals. Thirdly, we explored trends in a subset of conservation physiology articles published between 2006 and 2012. We identified a surge in the use of the term 'conservation physiology' in 2012, after only a slow increase in usage between 2006 and 2011. Conservation journals tend to have been significantly more active in publishing conservation physiology than animal physiology, plant physiology or ecology journals. However, we found evidence that ecology and animal physiology journals began to incorporate more conservation physiology after 2006, while conservation- and plant physiology-themed journals did not. Among 299 conservation physiology articles that we identified, vertebrate taxa have been over-represented in conservation physiology compared with their relative taxonomic abundance, invertebrate taxa have been under-represented, and plants have been represented in proportion to their relative taxonomic abundance; however, those findings are reasonably consistent with publication trends in conservation biology. Diffuse distribution of conservation physiology papers throughout the literature may have been a barrier to the growth of the subdiscipline when the interface was emerging. The introduction of the focused journal Conservation Physiology in 2013 may address that deficiency. Moreover, development of a unifying framework could help to aggregate knowledge and attract potential contributors by highlighting and facilitating access to and application of conservation physiology.

  13. Paleoenvironmental analyses of an organic deposit from an erosional landscape remnant, Arctic Coastal Plain of Alaska

    USGS Publications Warehouse

    Eisner, Wendy R.; Bockheim, James G.; Hinkel, Kenneth M.; Brown, Thomas A.; Nelson, Frederick E.; Peterson, Kim M.; Jones, Benjamin M.

    2005-01-01

    The dominant landscape process on the Arctic Coastal Plain of northern Alaska is the formation and drainage of thaw lakes. Lakes and drained thaw-lake basins account for approximately 75% of the modern surface expression of the Barrow Peninsula. The thaw-lake cycle usually obliterates lacustrine or peat sediments from previous cycles, which could otherwise be used for paleoecological reconstruction of long-term landscape and vegetation changes. Several possible erosional remnants of a former topographic surface that predates the formation of the thaw lakes have been tentatively identified. These remnants are characterized by a higher elevation, a thick organic layer with very high ground ice content in the upper permafrost and a plant community somewhat atypical of the region. Ten soil cores were collected from one site, and one core was intensively sampled for soil organic carbon content, pollen analysis and 14C dating. The lowest level of the organic sediments represents the earliest phase of plant growth and dates to ca. 9000 cal BP. Palynological evidence indicates the presence of mesic shrub tundra (including sedge, birch, willow and heath vegetation), and microfossil indicators point to wetter eutrophic conditions during this period. Carbon accumulation was rapid due to high net primary productivity in a relatively nutrient-rich environment. These results are interpreted as the local response to ameliorating climate during the early Holocene. The middle Holocene portion of the record contains an unconformity, indicating that between 8200 and 4200 cal BP sediments were eroded from the site, presumably in response to wind activity during a drier period centered around 4500 cal BP. The modern vegetation community of the erosional remnant was established after 4200 cal BP and peat growth resumed. During the late Holocene, carbon accumulation rates (CARs) were greatly reduced in response to the combined effects of declining productivity associated with climatic cooling, and increased nutrient stress as paludification and permafrost aggradation sequestered mineral nutrients.

  14. Paleoenvironmental analyses of an organic deposit from an erosional landscape remnant, Arctic Coastal Plain of Alaska

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Eisner, W R; Bockheim, J G; Hinkel, K M

    2005-01-02

    The dominant landscape process on the Arctic Coastal Plain of northern Alaska is the formation and drainage of thaw lakes. Lakes and drained thaw lake basins account for approximately 75% of the modern surface expression of the Barrow Peninsula. The thaw lake cycle usually obliterates lacustrine or peat sediments from previous cycles which could otherwise be used for paleoecological reconstruction of long-term landscape and vegetation changes. Several possible erosional remnants of a former topographic surface that predates the formation of the thaw lakes have been tentatively identified. These remnants are characterized by a higher elevation, a thick organic layer withmore » very high ground ice content in the upper permafrost, and a plant community somewhat atypical of the region. Ten soil cores were collected from one site, and one core was intensively sampled for soil organic carbon content, pollen analysis, and {sup 14}C dating. The lowest level of the organic sediments represents the earliest phase of plant growth and dates to ca. 9000 cal BP. Palynological evidence indicates the presence of mesic shrub tundra (including sedge, birch, willow, and heath vegetation); and microfossil indicators point to wetter eutrophic conditions during this period. Carbon accumulation was rapid due to high net primary productivity in a relatively nutrient-rich environment. These results are interpreted as the local response to ameliorating climate during the early Holocene. The middle Holocene portion of the record contains an unconformity, indicating that between 8200 and 4200 cal BP sediments were eroded from the site, presumably in response to wind activity during a drier period centered around 4500 cal BP. The modern vegetation community of the erosional remnant was established after 4200 cal BP, and peat growth resumed. During the late Holocene, carbon accumulation rates were greatly reduced in response to the combined effects of declining productivity associated with climatic cooling, and increased nutrient stress as paludification and permafrost aggradation sequestered mineral nutrients.« less

  15. Sand fly population dynamics and cutaneous leishmaniasis among soldiers in an Atlantic forest remnant in northeastern Brazil.

    PubMed

    Dantas-Torres, Filipe; Sales, Kamila Gaudêncio da Silva; Miranda, Débora Elienai de Oliveira; da Silva, Fernando José; Figueredo, Luciana Aguiar; de Melo, Fábio Lopes; de Brito, Maria Edileuza Felinto; Andrade, Maria Sandra; Brandão-Filho, Sinval Pinto

    2017-02-01

    Outbreaks of cutaneous leishmaniasis are relatively common among soldiers involved in nocturnal activities in tropical forests. We investigated the population dynamics of sand flies in a military training camp located in a remnant of Atlantic rainforest in northeastern Brazil, where outbreaks of cutaneous leishmaniasis have sporadically been described. From July 2012 to July 2014, light traps were monthly placed in 10 collection sites, being nine sites located near the forest edge and one near a sheep and goat stable. Light traps operated from 5:00 pm to 6:00 am, during four consecutive nights. Leishmania infection in sand flies was assessed using a fast real-time PCR assay. Cases of cutaneous leishmaniasis among soldiers were also investigated. In total, 24,606 sand flies belonging to 25 species were identified. Males (n = 12,683) predominated over females (n = 11,923). Sand flies were present during all months, being more numerous in March (n = 1,691) and April 2013 (n = 3,324). Lutzomyia choti (72.9%) was the most abundant species, followed by Lutzomyia longispina (13.8%), Lutzomyia complexa (5.3%), representing together >90% of the sand flies collected. Forty cases of cutaneous leishmaniasis were recorded among soldiers from January 2012 to December 2014. Leishmania isolates were obtained from eight patients and were all characterized as Leishmania braziliensis. Soldiers and anyone overnighting in Atlantic rainforest remnants should adopt preventative measures such as the use of repellents on bare skin or clothes and insecticide-treated tents.

  16. Sand fly population dynamics and cutaneous leishmaniasis among soldiers in an Atlantic forest remnant in northeastern Brazil

    PubMed Central

    Sales, Kamila Gaudêncio da Silva; Miranda, Débora Elienai de Oliveira; da Silva, Fernando José; Figueredo, Luciana Aguiar; de Melo, Fábio Lopes; de Brito, Maria Edileuza Felinto; Andrade, Maria Sandra; Brandão-Filho, Sinval Pinto

    2017-01-01

    Outbreaks of cutaneous leishmaniasis are relatively common among soldiers involved in nocturnal activities in tropical forests. We investigated the population dynamics of sand flies in a military training camp located in a remnant of Atlantic rainforest in northeastern Brazil, where outbreaks of cutaneous leishmaniasis have sporadically been described. From July 2012 to July 2014, light traps were monthly placed in 10 collection sites, being nine sites located near the forest edge and one near a sheep and goat stable. Light traps operated from 5:00 pm to 6:00 am, during four consecutive nights. Leishmania infection in sand flies was assessed using a fast real-time PCR assay. Cases of cutaneous leishmaniasis among soldiers were also investigated. In total, 24,606 sand flies belonging to 25 species were identified. Males (n = 12,683) predominated over females (n = 11,923). Sand flies were present during all months, being more numerous in March (n = 1,691) and April 2013 (n = 3,324). Lutzomyia choti (72.9%) was the most abundant species, followed by Lutzomyia longispina (13.8%), Lutzomyia complexa (5.3%), representing together >90% of the sand flies collected. Forty cases of cutaneous leishmaniasis were recorded among soldiers from January 2012 to December 2014. Leishmania isolates were obtained from eight patients and were all characterized as Leishmania braziliensis. Soldiers and anyone overnighting in Atlantic rainforest remnants should adopt preventative measures such as the use of repellents on bare skin or clothes and insecticide-treated tents. PMID:28241005

  17. Physiologically induced color-pattern changes in butterfly wings: mechanistic and evolutionary implications.

    PubMed

    Otaki, Joji M

    2008-07-01

    A mechanistic understanding of the butterfly wing color-pattern determination can be facilitated by experimental pattern changes. Here I review physiologically induced color-pattern changes in nymphalid butterflies and their mechanistic and evolutionary implications. A type of color-pattern change can be elicited by elemental changes in size and position throughout the wing, as suggested by the nymphalid groundplan. These changes of pattern elements are bi-directional and bi-sided dislocation toward or away from eyespot foci and in both proximal and distal sides of the foci. The peripheral elements are dislocated even in the eyespot-less compartments. Anterior spots are more severely modified, suggesting the existence of an anterior-posterior gradient. In one species, eyespots are transformed into white spots with remnant-like orange scales, and such patterns emerge even at the eyespot-less "imaginary" foci. A series of these color-pattern modifications probably reveal "snap-shots" of a dynamic morphogenic signal due to heterochronic uncoupling between the signaling and reception steps. The conventional gradient model can be revised to account for these observed color-pattern changes.

  18. [Recurrent neck abscess due to a branchial cleft remnant].

    PubMed

    Kruijff, Schelto; Mastboom, Walter J; Vriens, Menno R; Sidhu, Stan B; Delbridge, Leigh W

    2013-01-01

    Abscesses arising from a third or fourth branchial cleft remnant are uncommon clinical entities and are often not recognised in a timely manner. In a 33-year-old female patient with a recurrent abscess in the left side of her neck, the cause turned out to be a fistula in the third branchial cleft remnant. She was treated initially with antibiotics and prednisone without adequate results. When the abscess was finally surgically drained, she became very ill and was admitted to the ICU with sepsis and multiple organ failure. She was discharged from hospital after six weeks. Four months later, a third-branchial cleft remnant was found during pharyngoscopy, immediately after which the cleft remnant fistula was excised and an ipsilateral hemi-thyroidectomy was performed. In young patients with recurring peri-thyroidal abscesses, a branchial cleft remnant should be considered a causative factor; this could avoid high morbidity and a delay in the appropriate treatment.

  19. Supernova Explosions Stay In Shape

    NASA Astrophysics Data System (ADS)

    2009-12-01

    At a very early age, children learn how to classify objects according to their shape. Now, new research suggests studying the shape of the aftermath of supernovas may allow astronomers to do the same. A new study of images from NASA's Chandra X-ray Observatory on supernova remnants - the debris from exploded stars - shows that the symmetry of the remnants, or lack thereof, reveals how the star exploded. This is an important discovery because it shows that the remnants retain information about how the star exploded even though hundreds or thousands of years have passed. "It's almost like the supernova remnants have a 'memory' of the original explosion," said Laura Lopez of the University of California at Santa Cruz, who led the study. "This is the first time anyone has systematically compared the shape of these remnants in X-rays in this way." Astronomers sort supernovas into several categories, or "types", based on properties observed days after the explosion and which reflect very different physical mechanisms that cause stars to explode. But, since observed remnants of supernovas are leftover from explosions that occurred long ago, other methods are needed to accurately classify the original supernovas. Lopez and colleagues focused on the relatively young supernova remnants that exhibited strong X-ray emission from silicon ejected by the explosion so as to rule out the effects of interstellar matter surrounding the explosion. Their analysis showed that the X-ray images of the ejecta can be used to identify the way the star exploded. The team studied 17 supernova remnants both in the Milky Way galaxy and a neighboring galaxy, the Large Magellanic Cloud. For each of these remnants there is independent information about the type of supernova involved, based not on the shape of the remnant but, for example, on the elements observed in it. The researchers found that one type of supernova explosion - the so-called Type Ia - left behind relatively symmetric, circular remnants. This type of supernova is thought to be caused by a thermonuclear explosion of a white dwarf, and is often used by astronomers as "standard candles" for measuring cosmic distances. On the other hand, the remnants tied to the "core-collapse" supernova explosions were distinctly more asymmetric. This type of supernova occurs when a very massive, young star collapses onto itself and then explodes. "If we can link supernova remnants with the type of explosion", said co-author Enrico Ramirez-Ruiz, also of University of California, Santa Cruz, "then we can use that information in theoretical models to really help us nail down the details of how the supernovas went off." Models of core-collapse supernovas must include a way to reproduce the asymmetries measured in this work and models of Type Ia supernovas must produce the symmetric, circular remnants that have been observed. Out of the 17 supernova remnants sampled, ten were classified as the core-collapse variety, while the remaining seven of them were classified as Type Ia. One of these, a remnant known as SNR 0548-70.4, was a bit of an "oddball". This one was considered a Type Ia based on its chemical abundances, but Lopez finds it has the asymmetry of a core-collapse remnant. "We do have one mysterious object, but we think that is probably a Type Ia with an unusual orientation to our line of sight," said Lopez. "But we'll definitely be looking at that one again." While the supernova remnants in the Lopez sample were taken from the Milky Way and its close neighbor, it is possible this technique could be extended to remnants at even greater distances. For example, large, bright supernova remnants in the galaxy M33 could be included in future studies to determine the types of supernova that generated them. The paper describing these results appeared in the November 20 issue of The Astrophysical Journal Letters. NASA's Marshall Space Flight Center in Huntsville, Ala., manages the Chandra program for NASA's Science Mission Directorate in Washington. The Smithsonian Astrophysical Observatory controls Chandra's science and flight operations from Cambridge, Mass. More information, including images and other multimedia, can be found at: http://chandra.harvard.edu and http://chandra.nasa.gov

  20. The effect of remnant forest on insect successional response in tropical fire-impacted peatland: A bi-taxa comparison.

    PubMed

    Neoh, Kok-Boon; Bong, Lee-Jin; Muhammad, Ahmad; Itoh, Masayuki; Kozan, Osamu; Takematsu, Yoko; Yoshimura, Tsuyoshi

    2017-01-01

    Fire has become a common feature in tropical drained peatlands, and it may have detrimental impacts on the overall biodiversity of the forest ecosystem. We investigated the effect of fire on termite and ant assemblages and the importance of remnant forest in restoring species diversity in fire-impacted tropical peat swamp forests. The species loss of both termites and ants was as high as 50% in some fire-impacted peats compared to remnant forests, but in most cases the species richness for termites and ants was statistically equal along the land uses surveyed. However, a pronounced difference in functional group composition of termites was detected. In particular, sites close to remnant forests contained two additional termite feeding groups so that they shared a similar composition structure with remnant forests but were significantly different from sites distant from remnant forests. In general, ants were resilient to fire, and the similarity index showed a high degree of similarity among ant communities in all land uses surveyed. The Shannon diversity index for termites and ants decreased with increasing distance from the remnant forests and level of ecological degradation. Peat vegetation variables and ecological degradation were important in shaping termite and ant communities in the tropical peatlands, but their relative importance was not significant in fire-impacted peats regardless of distance from the remnant forests. This study highlights the importance of remnant forests as a biodiversity repository and natural buffer that can enhance species diversity and recolonization of forest-adapted species.

  1. The effect of remnant forest on insect successional response in tropical fire-impacted peatland: A bi-taxa comparison

    PubMed Central

    Neoh, Kok-Boon; Bong, Lee-Jin; Muhammad, Ahmad; Itoh, Masayuki; Kozan, Osamu; Takematsu, Yoko; Yoshimura, Tsuyoshi

    2017-01-01

    Fire has become a common feature in tropical drained peatlands, and it may have detrimental impacts on the overall biodiversity of the forest ecosystem. We investigated the effect of fire on termite and ant assemblages and the importance of remnant forest in restoring species diversity in fire-impacted tropical peat swamp forests. The species loss of both termites and ants was as high as 50% in some fire-impacted peats compared to remnant forests, but in most cases the species richness for termites and ants was statistically equal along the land uses surveyed. However, a pronounced difference in functional group composition of termites was detected. In particular, sites close to remnant forests contained two additional termite feeding groups so that they shared a similar composition structure with remnant forests but were significantly different from sites distant from remnant forests. In general, ants were resilient to fire, and the similarity index showed a high degree of similarity among ant communities in all land uses surveyed. The Shannon diversity index for termites and ants decreased with increasing distance from the remnant forests and level of ecological degradation. Peat vegetation variables and ecological degradation were important in shaping termite and ant communities in the tropical peatlands, but their relative importance was not significant in fire-impacted peats regardless of distance from the remnant forests. This study highlights the importance of remnant forests as a biodiversity repository and natural buffer that can enhance species diversity and recolonization of forest-adapted species. PMID:28334021

  2. Is Remnant Preservation Truly Beneficial to Anterior Cruciate Ligament Reconstruction Healing? Clinical and Magnetic Resonance Imaging Evaluations of Remnant-Preserved Reconstruction.

    PubMed

    Naraoka, Takuya; Kimura, Yuka; Tsuda, Eiichi; Yamamoto, Yuji; Ishibashi, Yasuyuki

    2017-04-01

    Remnant-preserved anterior cruciate ligament (ACL) reconstruction was introduced to improve clinical outcomes and biological healing. However, the effects of remnant preservation and the influence of the delay from injury until reconstruction on the outcomes of this technique are still uncertain. Purpose/Hypothesis: The purposes of this study were to evaluate whether remnant preservation improved the clinical outcomes and graft incorporation of ACL reconstruction and to examine the influence of the delay between ACL injury and reconstruction on the usefulness of remnant preservation. We hypothesized that remnant preservation improves clinical results and accelerates graft incorporation and that its effect is dependent on the delay between ACL injury and reconstruction. Cohort study; Level of evidence, 2. A total of 151 consecutive patients who underwent double-bundle ACL reconstruction using a semitendinosus graft were enrolled in this study: 74 knees underwent ACL reconstruction without a remnant (or the remnant was <25% of the intra-articular portion of the graft; NR group), while 77 knees underwent ACL reconstruction with remnant preservation (RP group). These were divided into 4 subgroups based on the time from injury to surgery: phase 1 was <3 weeks (n = 24), phase 2 was 3 to less than 8 weeks (n = 70), phase 3 was 8 to 20 weeks (n = 32), and phase 4 was >20 weeks (n = 25). Clinical measurements, including KT-1000 arthrometer side-to-side anterior tibial translation measurements, were assessed at 3, 6, 12, and 24 months after reconstruction. Magnetic resonance imaging evaluations of graft maturation and graft-tunnel integration of the anteromedial and posterolateral bundles were assessed at 3, 6, and 12 months after reconstruction. There was no difference in side-to-side anterior tibial translation between the NR and RP groups. There was also no difference in graft maturation between the 2 groups. Furthermore, the time from ACL injury until reconstruction did not affect graft maturation, except in the case of very long delays before reconstruction (phase 4). Graft-tunnel integration was significantly increased in both groups in a time-dependent manner. However, there was no difference between the NR and RP groups. Remnant preservation did not improve knee stability at 2 years after ACL reconstruction. Furthermore, remnant preservation did not accelerate graft incorporation, especially during the acute and subacute injury phases.

  3. Difficulties in deciding whether to ablate patients with putatively "low-intermediate-risk" differentiated thyroid carcinoma: do guidelines mainly apply in the centres that produce them? Results of a retrospective, two-centre quality assurance study.

    PubMed

    Frangos, Savvas; Iakovou, Ioannis P; Marlowe, Robert J; Eftychiou, Nicolaos; Patsali, Loukia; Vanezi, Anna; Savva, Androulla; Mpalaris, Vassilis; Giannoula, Evanthia I

    2015-12-01

    We determined the reasons for radioiodine thyroid remnant ablation, and the procedure's necessity based on postsurgical remnant size, in patients with putatively "low-intermediate-risk" differentiated thyroid carcinoma (DTC). We identified key clinicopathological, treatment and remnant characteristics, and factors associated with remnant size in 336 patients with pT1/2, M0 DTC ablated during the period September 2010 to October 2013 at one Cypriot or one Greek referral centre. Clinicopathological/treatment characteristics were compiled from charts. Experienced nuclear medicine physicians rated the numbers/intensities of uptake foci in the thyroid bed on postablation planar scintigrams using scales of 0-4 points and 0-3 points, respectively. The product of these scores was taken as the "remnant score" that ranged from 0 (no remnant) to 12 (multiple remnants, intense uptake). DTC was predominantly papillary. The median [25th-75th percentile] longest primary tumour diameter was 1.0 cm [0.7-1.5 cm]. Despite favourable histotypes and primary tumour classifications, patients often had preablation characteristics suggesting elevated or uncertain risk: 31.0% of patients (104 of 336) had primary tumour multifocality, 22.0% (74) had confirmed cervical lymph node metastases, 37.2% (125) had unknown nodal status, and 38.1% (128) had antithyroglobulin antibody seropositivity. The median [25th-75th percentile] remnant score was 4 [2-6]; 39.9% of patients (134 of 336) had scores ≥6. For the entire cohort, T or N stages (r ≤ 0.174, P ≤ 0.05) correlated positively with the remnant score in a univariate Spearman analysis. The numbers of patients referred by the surgeon, cervical lymph nodes excised and metastatic nodes excised correlated negatively (r ≤ 0.243, P ≤ 0.038) with the remnant score, and the first two factors independently predicted the remnant score (P ≤ 0.037) in a multivariate analysis. Patients with putatively "low-intermediate-risk" DTC frequently had disease characteristics denoting high or uncertain risk, suggesting that "selective" radioiodine ablation in such patients may seldom be applicable outside international centres of excellence. Proxies for surgeon experience and surgical completeness correlated with remnant number/uptake intensity and may aid ablation-related decision-making.

  4. Dance of the Light Echoes

    NASA Technical Reports Server (NTRS)

    2008-01-01

    [figure removed for brevity, see original site] Click on image for larger poster version

    This composite image from NASA's Spitzer Space Telescope shows the remnant of a star that exploded, called Cassiopeia A (center) and its surrounding 'light echoes' -- dances of light through dusty clouds, created when stars blast apart. The light echoes are colored and the surrounding clouds of dust are gray.

    In figure 1, dramatic changes are highlighted in phenomena referred to as light echoes (colored areas) around the Cassiopeia A supernova remnant (center). Cassiopeia A is the remnant of a once massive star that died in a violent supernova explosion. It consists of a dead star, called a neutron star, and a surrounding shell of material that was blasted off as the star died.

    A light echo occurs when a star explodes, acting like a cosmic flashbulb. The light from this explosion zips through nearby dust clumps, illuminating and heating them up slightly. This brief period of warming causes them to glow in infrared, like a chain of Christmas bulbs lighting up one by one. The result is an optical illusion, in which the dust appears to be flying outward at the speed of light. In figure 1, this apparent motion can be seen here by the shift in colored dust clumps

    Cassiopeia A is the remnant of a once massive star that died in a violent supernova explosion. It consists of a dead star, called a neutron star, and a surrounding shell of material that was blasted off as the star died. This remnant is located 11,000 light-years away in the northern constellation Cassiopeia.

    This composite consists of six processed images taken over a time span of three years. Dust features that have not changed over time appear gray, while those that have changed are colored blue or orange. Bluer colors represent an earlier time and redder ones, a later time. The progression of the light echo through the dust can be seen here by the shift in colored dust clumps.

    This light echo is the largest ever seen, stretching more than 300 light-years away from Cassiopeia A. If viewed from Earth, the entire frame would take up the same amount of space as seven full moons. The supernova remnant is located 11,000 light-years away in the northern constellation Cassiopeia.

    The earliest Spitzer image shown here was taken in February 2005, and the latest one in January 2008. The image was processed to emphasize the light echo by enhancing the areas that change, which appear in color, and dimming regions that remain constant, seen in grayscale. Spurious color artifacts such as diffraction spikes around stars were removed by hand.

  5. Environmental effects of the Big Rapids dam remnant removal, Big Rapids, Michigan, 2000-02

    USGS Publications Warehouse

    Healy, Denis F.; Rheaume, Stephen J.; Simpson, J. Alan

    2003-01-01

    The U.S. Geological Survey (USGS), in cooperation with the city of Big Rapids, investigated the environmental effects of removal of a dam-foundation remnant and downstream cofferdam from the Muskegon River in Big Rapids, Mich. The USGS applied a multidiscipline approach, which determined the water quality, sediment character, and stream habitat before and after dam removal. Continuous water-quality data and discrete water-quality samples were collected, the movement of suspended and bed sediment were measured, changes in stream habitat were assessed, and streambed elevations were surveyed. Analyses of water upstream and downstream from the dam showed that the dam-foundation remnant did not affect water quality. Dissolved-oxygen concentrations downstream from the dam remnant were depressed for a short period (days) during the beginning of the dam removal, in part because of that removal effort. Sediment transport from July 2000 through March 2002 was 13,800 cubic yards more at the downstream site than the upstream site. This increase in sediment represents the remobilized sediment upstream from the dam, bank erosion when the impoundment was lowered, and contributions from small tributaries between the sites. Five habitat reaches were monitored before and after dam-remnant removal. The reaches consisted of a reference reach (A), upstream from the effects of the impoundment; the impoundment (B); and three sites below the impoundment where habitat changes were expected (C, D, and E, in downstream order). Stream-habitat assessment reaches varied in their responses to the dam-remnant removal. Reference reach A was not affected. In impoundment reach B, Great Lakes and Environmental Assessment Section (GLEAS) Procedure 51 ratings went from fair to excellent. For the three downstream reaches, reach C underwent slight habitat degradation, but ratings remained good; reach D underwent slight habitat degradation with ratings changing from excellent to good; and, in an area affected by a 1966 sediment release, reach E habitat rated fair in April 2000 and remained fair in September 2001. The most noticeable habitat change in the three reaches downstream from the dam site was a measurable increase in siltation and embeddedness. Bed-elevation profiles show that bed material upstream from the dam site was remobilized as suspended sediment and bedload, and was redeposited in the reaches below the cofferdam. Deposition was greater in the deep, slow-moving pools than the shallow, fast-moving riffles. For the most part, where deposition took place, deposits were less than 1 foot in thickness. In the year following the removal of the cofferdam, much of the sediment deposited below the dam was moved out of the study reach.

  6. State of the interface between conservation and physiology: a bibliometric analysis

    PubMed Central

    Lennox, Robert; Cooke, Steven J.

    2014-01-01

    Contemporary conservation science benefits from the perspectives of a variety of different disciplines, including a recent synergy with physiology, an interface known as ‘conservation physiology’. To evaluate the degree of interaction between conservation and animal/plant physiology, we conducted three bibliometric analyses. We first pursued the use of the term ‘conservation physiology’ since its first definition in 2006 to determine how frequently it has been used and in which publications. Secondly, we evaluated the occurrence of conservation terms in animal and plant physiology journals, physiological terms in conservation journals, and a combination of terms in ecology journals. Thirdly, we explored trends in a subset of conservation physiology articles published between 2006 and 2012. We identified a surge in the use of the term ‘conservation physiology’ in 2012, after only a slow increase in usage between 2006 and 2011. Conservation journals tend to have been significantly more active in publishing conservation physiology than animal physiology, plant physiology or ecology journals. However, we found evidence that ecology and animal physiology journals began to incorporate more conservation physiology after 2006, while conservation- and plant physiology-themed journals did not. Among 299 conservation physiology articles that we identified, vertebrate taxa have been over-represented in conservation physiology compared with their relative taxonomic abundance, invertebrate taxa have been under-represented, and plants have been represented in proportion to their relative taxonomic abundance; however, those findings are reasonably consistent with publication trends in conservation biology. Diffuse distribution of conservation physiology papers throughout the literature may have been a barrier to the growth of the subdiscipline when the interface was emerging. The introduction of the focused journal Conservation Physiology in 2013 may address that deficiency. Moreover, development of a unifying framework could help to aggregate knowledge and attract potential contributors by highlighting and facilitating access to and application of conservation physiology. PMID:27293624

  7. CHARACTERISTICS OF EPIRETINAL MEMBRANE REMNANT EDGE BY OPTICAL COHERENCE TOMOGRAPHY AFTER PARS PLANA VITRECTOMY.

    PubMed

    Gaber, Raouf; You, Qi Sheng; Muftuoglu, Ilkay Kilic; Alam, Mostafa; Tsai, Frank F; Mendoza, Nadia; Freeman, William R

    2017-11-01

    To evaluate the incidence, characteristics, and the progression of epiretinal membrane (ERM) remnant edge seen by optical coherence tomography after ERM peeling. A retrospective chart review was conducted for 86 eyes of 85 consecutive patients who were diagnosed with ERM and underwent pars plana vitrectomy for epiretinal membrane peeling between 2013 and 2014. Data collected and analyzed included age, gender, preoperative and postoperative visual acuity, use of indocyanine green dye to stain internal limiting membrane, tamponade used after vitrectomy, ERM edge boundaries, presence of cystoid macular edema, and central foveal thickness. An ERM remnant edge was detected in 33/86 study eyes (38.4%) at the first postoperative optical coherence tomography scan. Compared with those without an ERM remnant, patients with an ERM remnant after surgery were significantly older at baseline and had a higher incidence of ERM recurrence at their last visit. They were not significantly different in terms of gender, preoperative and postoperative visual acuity, reduction of central foveal thickness from baseline, proportion of eyes with preoperative ERM elevation on optical coherence tomography, presence of macular edema before surgery, intraoperative use of indocyanine green staining for ILM peeling, or tamponade used. Based on the edge morphology, we classified the ERM remnant into three types: Type 1 was flat and blended with the retina (14/33 eyes, 42.4%), Type 2 was flat but stepped (17/33 eyes, 51.5%), and Type 3 was elevated (2/33 eyes, 6.0%). A significantly higher risk of ERM recurrence was seen in Type 2 and Type 3 ERM remnants (75% and 100%, respectively) than Type 1 ERM remnants (10%). An ERM remnant edge was detected by optical coherence tomography after ERM peeling in 38.4% of eyes. The presence of a postoperative ERM edge was associated with a higher risk of ERM recurrence, particularly in Type 2 and Type 3 ERM remnants.

  8. Remnant Cholesterol Elicits Arterial Wall Inflammation and a Multilevel Cellular Immune Response in Humans.

    PubMed

    Bernelot Moens, Sophie J; Verweij, Simone L; Schnitzler, Johan G; Stiekema, Lotte C A; Bos, Merijn; Langsted, Anne; Kuijk, Carlijn; Bekkering, Siroon; Voermans, Carlijn; Verberne, Hein J; Nordestgaard, Børge G; Stroes, Erik S G; Kroon, Jeffrey

    2017-05-01

    Mendelian randomization studies revealed a causal role for remnant cholesterol in cardiovascular disease. Remnant particles accumulate in the arterial wall, potentially propagating local and systemic inflammation. We evaluated the impact of remnant cholesterol on arterial wall inflammation, circulating monocytes, and bone marrow in patients with familial dysbetalipoproteinemia (FD). Arterial wall inflammation and bone marrow activity were measured using 18 F-FDG PET/CT. Monocyte phenotype was assessed with flow cytometry. The correlation between remnant levels and hematopoietic activity was validated in the CGPS (Copenhagen General Population Study). We found a 1.2-fold increase of 18 F-FDG uptake in the arterial wall in patients with FD (n=17, age 60±8 years, remnant cholesterol: 3.26 [2.07-5.71]) compared with controls (n=17, age 61±8 years, remnant cholesterol 0.29 [0.27-0.40]; P <0.001). Monocytes from patients with FD showed increased lipid accumulation (lipid-positive monocytes: Patients with FD 92% [86-95], controls 76% [66-81], P =0.001, with an increase in lipid droplets per monocyte), and a higher expression of surface integrins (CD11b, CD11c, and CD18). Patients with FD also exhibited monocytosis and leukocytosis, accompanied by a 1.2-fold increase of 18 F-FDG uptake in bone marrow. In addition, we found a strong correlation between remnant levels and leukocyte counts in the CGPS (n=103 953, P for trend 5×10-276). In vitro experiments substantiated that remnant cholesterol accumulates in human hematopoietic stem and progenitor cells coinciding with myeloid skewing. Patients with FD have increased arterial wall and cellular inflammation. These findings imply an important inflammatory component to the atherogenicity of remnant cholesterol, contributing to the increased cardiovascular disease risk in patients with FD. © 2017 American Heart Association, Inc.

  9. Healing Potential of the Anterior Cruciate Ligament Remnant Stump.

    PubMed

    Trocan, Ilie; Ceausu, Raluca A; Jitariu, Andreea A; Haragus, Horia; Damian, Gratian; Raica, Marius

    2016-01-01

    The aim of this study was to analyze the microstructural architecture and cellular differentiation of the anterior cruciate ligament (ACL) stumps in different stages after injury, as this could augment graft biointegration. The histological appearance and immunoreaction for cluster of differentiation 34 antigen (CD34) of 54 biopsies from 27 remnants were compared to 10 biopsies from 5 normal cruciate ligaments. CD34 reaction in endothelial cells, fibroblasts and fibrocytes was consistently positive in small synovial vessels. Remnants also exhibited CD34(+) cells among collagen fibers. Blood vessel density varied between specimens. The mean vascular microdensity was 43 per ×200 field in remnants compared to 15.2 in controls. A total of 94.44% of remnant ACL samples had significant hyperplasia of stellate and fusiform stromal cells, CD34(+); 22.4% had developed capillary vessels inside the ligament; 33% exhibited ongoing angiogenesis. Significant differences exist between torn and intact ACL regarding microvascularization. The remnants contain stellate stromal cells and CD34(+) fibrocytes, and display angiogenesis both at synovia as well as in the ligament itself. These findings underline the potential contribution to neoligament healing when remnants are preserved. Copyright © 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

  10. Complex branchial fistula: a variant arch anomaly.

    PubMed

    De Caluwé, D; Hayes, R; McDermott, M; Corbally, M T

    2001-07-01

    A 5-year-old boy presented with an infected left-sided branchial fistula. Despite antibiotic treatment and repeated excision of the fistula, purulent discharge from the wound persisted. Three-dimensional computed tomography (3D CT) reconstruction greatly facilitated the diagnosis and management of this case by showing the course of the fistulous tract. The complexity of the tract suggests that this represents a variant arch anomaly because it contains features of first, second, third, and fourth arch remnants. Copyright 2001 by W.B. Saunders Company.

  11. Remnant field detector

    DOEpatents

    Visser, Age T.

    1988-05-03

    A method apparatus for qualitatively detecting remnant magnetic fields in matched pairs of magnet cores. Equal magnitude and oppositely oriented magnetic flux is induced in the magnet cores by oppositely wound primary windings and current source. Identically wound secondary windings generate output voltages in response to the induced flux. The output voltages generated should be of equal magnitude and opposite polarity if there is no remnant field in the cores. The output voltages will be unequal which is detected if either core has a remnant field.

  12. Remnant field detector

    DOEpatents

    Visser, Age T.

    1988-01-01

    A method apparatus for qualitatively detecting remnant magnetic fields in matched pairs of magnet cores. Equal magnitude and oppositely oriented magnetic flux is induced in the magnet cores by oppositely wound primary windings and current source. Identically wound secondary windings generate output voltages in response to the induced flux. The output voltages generated should be of equal magnitude and opposite polarity if there is no remnant field in the cores. The output voltages will be unequal which is detected if either core has a remnant field.

  13. Cervical Chondrocutaneous Branchial Remnants.

    PubMed

    Klockars, Tuomas; Kajosaari, Lauri

    2017-03-01

      Cervical chondrocutaneous branchial remnants are rare malformations usually found in the lower neck. As high as 76% of patients have been reported to have associated anomalies. We review the literature and report a case series of seven patients with cervical cartilaginous remnants.   A retrospective case series of seven patients identified from the electronic hospital records.   Seven patients with cervical chondrocutaneous branchial remnants were identified (six boys and one girl). Only one of the patients had associated anomalies.   A review of the literature revealed no evidence for sinuses or cysts related to cervical chondrocutaneous branchial remnants. Operative treatment can be postponed to a suitable and safe age. There is marked variation in the reported prevalence of associated anomalies, ranging from 11% to 76%.

  14. Expansion of Kes 73, a shell supernova remnant containing a magnetar

    NASA Astrophysics Data System (ADS)

    Borkowski, Kazimierz

    2014-09-01

    Formation and evolution of highly magnetized neutron stars (magnetars) remain poorly understood. We can learn about magnetars by studying their remnants. Kes 73 is a young supernova remnant containing a magnetar. But basic properties of Kes 73, including its age, remain poorly known. We propose a third-epoch observation of Kes 73 with Chandra. When combined with the 2000 and 2006 observations, this will allow for determination of the remnant's age through expansion rate measurements. We will also search for spatial variations in expansion rate that will help in understanding of the remnant's dynamics. New observations will also be used to determine abundances of heavy-element supernova ejecta, placing further constraints on the supernova that produced Kes 73.

  15. 44Ti Nucleosynthesis Lines and Hard X-ray Continuum in Young SNRs: from INTEGRAL to Simbol-X

    NASA Astrophysics Data System (ADS)

    Renaud, M.; Terrier, R.; Trap, G.; Lebrun, F.; Decourchelle, A.; Vink, J.

    2009-05-01

    Supemovae and their remnants are the main Galactic nucleosynthesis sites and the privileged sources of Galactic cosmic rays. The youngest of such remnants can be studied through two distinct observational features: 44Ti γ-ray lines and the hard X-ray nonthermal continuum emission. The former gives unique information on the nucleosynthesis conditions occuring during the first stages of the explosion, while the latter provides clues on acceleration processes at supernova remnant shocks. In this contribution, we present new INTEGRAL results on Tycho, the remnant of a historical supernova, and on G1.9+0.3, which has been recently unveiled as the youngest Galactic supernova remnant. Expectations with Simbol-X are also addressed.

  16. 27 CFR 19.389 - Remnants.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Remnants. 19.389 Section 19.389 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF... Manufacture of Articles Bottling, Packaging, and Removal of Products § 19.389 Remnants. Where incident to...

  17. HESS J1818-154, a new composite supernova remnant discovered in TeV gamma rays and X-rays

    NASA Astrophysics Data System (ADS)

    H. E. S. S. Collaboration; Abramowski, A.; Aharonian, F.; Ait Benkhali, F.; Akhperjanian, A. G.; Angüner, E.; Anton, G.; Balenderan, S.; Balzer, A.; Barnacka, A.; Becherini, Y.; Becker Tjus, J.; Bernlöhr, K.; Birsin, E.; Bissaldi, E.; Biteau, J.; Böttcher, M.; Boisson, C.; Bolmont, J.; Bordas, P.; Brucker, J.; Brun, F.; Brun, P.; Bulik, T.; Carrigan, S.; Casanova, S.; Cerruti, M.; Chadwick, P. M.; Chalme-Calvet, R.; Chaves, R. C. G.; Cheesebrough, A.; Chrétien, M.; Colafrancesco, S.; Cologna, G.; Conrad, J.; Couturier, C.; Cui, Y.; Dalton, M.; Daniel, M. K.; Davids, I. D.; Degrange, B.; Deil, C.; deWilt, P.; Dickinson, H. J.; Djannati-Ataï, A.; Domainko, W.; Drury, L. O'C.; Dubus, G.; Dutson, K.; Dyks, J.; Dyrda, M.; Edwards, T.; Egberts, K.; Eger, P.; Espigat, P.; Farnier, C.; Fegan, S.; Feinstein, F.; Fernandes, M. V.; Fernandez, D.; Fiasson, A.; Fontaine, G.; Förster, A.; Füßling, M.; Gajdus, M.; Gallant, Y. A.; Garrigoux, T.; Giavitto, G.; Giebels, B.; Glicenstein, J. F.; Grondin, M.-H.; Grudzińska, M.; Häffner, S.; Hahn, J.; Harris, J.; Heinzelmann, G.; Henri, G.; Hermann, G.; Hervet, O.; Hillert, A.; Hinton, J. A.; Hofmann, W.; Hofverberg, P.; Holler, M.; Horns, D.; Jacholkowska, A.; Jahn, C.; Jamrozy, M.; Janiak, M.; Jankowsky, F.; Jung, I.; Kastendieck, M. A.; Katarzyński, K.; Katz, U.; Kaufmann, S.; Khélifi, B.; Kieffer, M.; Klepser, S.; Klochkov, D.; Kluźniak, W.; Kneiske, T.; Kolitzus, D.; Komin, Nu.; Kosack, K.; Krakau, S.; Krayzel, F.; Krüger, P. P.; Laffon, H.; Lamanna, G.; Lefaucheur, J.; Lemière, A.; Lemoine-Goumard, M.; Lenain, J.-P.; Lennarz, D.; Lohse, T.; Lopatin, A.; Lu, C.-C.; Marandon, V.; Marcowith, A.; Marx, R.; Maurin, G.; Maxted, N.; Mayer, M.; McComb, T. J. L.; Méhault, J.; Meintjes, P. J.; Menzler, U.; Meyer, M.; Moderski, R.; Mohamed, M.; Moulin, E.; Murach, T.; Naumann, C. L.; de Naurois, M.; Niemiec, J.; Nolan, S. J.; Oakes, L.; Ohm, S.; de Oña Wilhelmi, E.; Opitz, B.; Ostrowski, M.; Oya, I.; Panter, M.; Parsons, R. D.; Paz Arribas, M.; Pekeur, N. W.; Pelletier, G.; Perez, J.; Petrucci, P.-O.; Peyaud, B.; Pita, S.; Poon, H.; Pühlhofer, G.; Punch, M.; Quirrenbach, A.; Raab, S.; Raue, M.; Reimer, A.; Reimer, O.; Renaud, M.; de los Reyes, R.; Rieger, F.; Rob, L.; Romoli, C.; Rosier-Lees, S.; Rowell, G.; Rudak, B.; Rulten, C. B.; Sahakian, V.; Sanchez, D. A.; Santangelo, A.; Schlickeiser, R.; Schüssler, F.; Schulz, A.; Schwanke, U.; Schwarzburg, S.; Schwemmer, S.; Sol, H.; Spengler, G.; Spies, F.; Stawarz, Ł.; Steenkamp, R.; Stegmann, C.; Stinzing, F.; Stycz, K.; Sushch, I.; Szostek, A.; Tavernet, J.-P.; Tavernier, T.; Taylor, A. M.; Terrier, R.; Tluczykont, M.; Trichard, C.; Valerius, K.; van Eldik, C.; van Soelen, B.; Vasileiadis, G.; Venter, C.; Viana, A.; Vincent, P.; Völk, H. J.; Volpe, F.; Vorster, M.; Vuillaume, T.; Wagner, S. J.; Wagner, P.; Ward, M.; Weidinger, M.; Weitzel, Q.; White, R.; Wierzcholska, A.; Willmann, P.; Wörnlein, A.; Wouters, D.; Zabalza, V.; Zacharias, M.; Zajczyk, A.; Zdziarski, A. A.; Zech, A.; Zechlin, H.-S.

    2014-02-01

    Composite supernova remnants (SNRs) constitute a small subclass of the remnants of massive stellar explosions where non-thermal radiation is observed from both the expanding shell-like shock front and from a pulsar wind nebula (PWN) located inside of the SNR. These systems represent a unique evolutionary phase of SNRs where observations in the radio, X-ray, and γ-ray regimes allow the study of the co-evolution of both these energetic phenomena. In this article, we report results from observations of the shell-type SNR G 15.4+0.1 performed with the High Energy Stereoscopic System (H.E.S.S.) and XMM-Newton. A compact TeV γ-ray source, HESS J1818-154, located in the center and contained within the shell of G 15.4+0.1 is detected by H.E.S.S. and featurs a spectrum best represented by a power-law model with a spectral index of -2.3 ± 0.3stat ± 0.2sys and an integral flux of F(> 0.42 TeV) = (0.9 ± 0.3stat ± 0.2sys) × 10-12 cm-2 s-1. Furthermore, a recent observation with XMM-Newton reveals extended X-ray emission strongly peaked in the center of G 15.4+0.1. The X-ray source shows indications of an energy-dependent morphology featuring a compact core at energies above 4 keV and more extended emission that fills the entire region within the SNR at lower energies. Together, the X-ray and VHE γ-ray emission provide strong evidence of a PWN located inside the shell of G 15.4+0.1 and this SNR can therefore be classified as a composite based on these observations. The radio, X-ray, and γ-ray emission from the PWN is compatible with a one-zone leptonic model that requires a low average magnetic field inside the emission region. An unambiguous counterpart to the putative pulsar, which is thought to power the PWN, has been detected neither in radio nor in X-ray observations of G 15.4+0.1.

  18. Extreme liver resections with preservation of segment 4 only

    PubMed Central

    Balzan, Silvio Marcio Pegoraro; Gava, Vinícius Grando; Magalhães, Marcelo Arbo; Dotto, Marcelo Luiz

    2017-01-01

    AIM To evaluate safety and outcomes of a new technique for extreme hepatic resections with preservation of segment 4 only. METHODS The new method of extreme liver resection consists of a two-stage hepatectomy. The first stage involves a right hepatectomy with middle hepatic vein preservation and induction of left lobe congestion; the second stage involves a left lobectomy. Thus, the remnant liver is represented by the segment 4 only (with or without segment 1, ± S1). Five patients underwent the new two-stage hepatectomy (congestion group). Data from volumetric assessment made before the second stage was compared with that of 10 matched patients (comparison group) that underwent a single-stage right hepatectomy with middle hepatic vein preservation. RESULTS The two stages of the procedure were successfully carried out on all 5 patients. For the congestion group, the overall volume of the left hemiliver had increased 103% (mean increase from 438 mL to 890 mL) at 4 wk after the first stage of the procedure. Hypertrophy of the future liver remnant (i.e., segment 4 ± S1) was higher than that of segments 2 and 3 (144% vs 54%, respectively, P < 0.05). The median remnant liver volume-to-body weight ratio was 0.3 (range, 0.28-0.40) before the first stage and 0.8 (range, 0.45-0.97) before the second stage. For the comparison group, the rate of hypertrophy of the left liver after right hepatectomy with middle hepatic vein preservation was 116% ± 34%. Hypertrophy rates of segments 2 and 3 (123% ± 47%) and of segment 4 (108% ± 60%, P > 0.05) were proportional. The mean preoperative volume of segments 2 and 3 was 256 ± 64 cc and increased to 572 ± 257 cc after right hepatectomy. Mean preoperative volume of segment 4 increased from 211 ± 75 cc to 439 ± 180 cc after surgery. CONCLUSION The proposed method for extreme hepatectomy with preservation of segment 4 only represents a technique that could allow complete resection of multiple bilateral liver metastases. PMID:28765703

  19. Investigating the Origin of the Supernova Remnant W49B

    NASA Astrophysics Data System (ADS)

    Crum, Ryan Matthew; Frank, Kari A.; Dwarkadas, Vikram; Burrows, David N.

    2018-01-01

    W49B is a Galactic supernova remnant whose origin is still debated. Is it the remains of an unusual asymmetric Type 1a supernova or of a jet-driven core collapse supernova? Using the X-ray analysis method, Smoothed Particle Inference (SPI), we dig deeper into understanding the complex properties of SNR W49B. We do this by characterizing the temperatures and abundance ratios throughout the remnant. We will compare the results with a wide variety of supernova nucleosynthesis models in order to constrain the mechanism behind this unusual supernova remnant.

  20. OT2_jhewitt_2: Understanding Shock Oxygen Chemistry in Interacting Supernova Remnants

    NASA Astrophysics Data System (ADS)

    Hewitt, J.

    2011-09-01

    Supernova remnants interacting with dense moelcular clouds provide astrochemical laboratories to study heating and cooling of the dense ISM, shock chemistry, destruction and sputtering of dust, and the reformation of molecules. Water is expected to be a major coolant for shocks into dense gas, yet the number of remnants in which IR lines of hydroxyl and water are detected is very limited. We propose Herschel PACS, SPIRE and HIFI observations of three remnants with particularly high shocked gas densities, high dust and IR line luinosities, and extreme ionization environments. The scientific objectives of this proposal are: (1) to determine the abundance and excitation of oxygen-bearing molecules, and (2) to study the effects of variable ionization sources on oxygen chemistry in dense molecular gas shocked by powerful supernova remnant blast waves.

  1. Are supernova remnants quasi-parallel or quasi-perpendicular accelerators

    NASA Technical Reports Server (NTRS)

    Spangler, S. R.; Leckband, J. A.; Cairns, I. H.

    1989-01-01

    Observations of shock waves in the solar system which show a pronounced difference in the plasma wave and particle environment depending on whether the shock is propagating along or perpendicular to the interplanetary magnetic field are discussed. Theories for particle acceleration developed for quasi-parallel and quasi-perpendicular shocks, when extended to the interstellar medium suggest that the relativistic electrons in radio supernova remnants are accelerated by either the Q parallel or Q perpendicular mechanisms. A model for the galactic magnetic field and published maps of supernova remnants were used to search for a dependence of structure on the angle Phi. Results show no tendency for the remnants as a whole to favor the relationship expected for either mechanism, although individual sources resemble model remnants of one or the other acceleration process.

  2. Clinical outcome of using gastric remnant or jejunum or colon conduit in surgery for esophageal carcinoma with previous gastrectomy.

    PubMed

    Jun, Wang; Wei, Wen; Weibing, Wu; Jing, Xu; Fuxi, Zhen; Xiaoxiang, Xi; Bihong, Lu; Tong, Zhou; Liang, Chen; Jinhua, Luo

    2017-05-01

    For esophageal carcinoma patients with early gastrectomy, individualized surgical plans-including selection of replacement conduit and operation route based on patient's new lesion and surgical history-can achieve the desired therapeutic effect and improve postoperative life quality. We investigated the outcomes at our institution. The clinical data of 42 esophageal carcinoma patients with early gastrectomy were analyzed retrospectively. Esophagectomy was performed combining replacement with remnant stomach in 16 patients, jejunum in 17, and colon in 9. Esophagectomy combining replacement with gastric remnant got advantages of shorter operation time and less bleeding over that of replacement with jejunum or colon. Gastric remnant group scored higher on the QLQ-C30 questionnaire than jejunum or colon group with respect to overall quality of life, physical function, and social relationships. In QLQ-OES18 questionnaire, the scores of appetite recovery and reflux mitigation were more favorable in remnant stomach group than those in jejunum or colon group. Survival analysis showed no significant difference in survival rate among the patients undergoing replacement with gastric remnant, jejunum, or colon. For esophageal carcinoma patients with early gastrectomy, esophagus-gastric remnant anastomosis possesses advantages of shorter operation time, less surgical trauma, and greater life quality after surgery. © 2017 Wiley Periodicals, Inc.

  3. Future remnant liver function as predictive factor for the hypertrophy response after portal vein embolization.

    PubMed

    Cieslak, Kasia P; Huisman, Floor; Bais, Thomas; Bennink, Roelof J; van Lienden, Krijn P; Verheij, Joanne; Besselink, Marc G; Busch, Olivier R C; van Gulik, Thomas M

    2017-07-01

    Preoperative portal vein embolization is widely used to increase the future remnant liver. Identification of nonresponders to portal vein embolization is essential because these patients may benefit from associating liver partition and portal vein ligation for staged hepatectomy (ALPPS), which induces a more powerful hypertrophy response. 99m Tc-mebrofenin hepatobiliary scintigraphy is a quantitative method for assessment of future remnant liver function with a calculated cutoff value for the prediction of postoperative liver failure. The aim of this study was to analyze future remnant liver function before portal vein embolization to predict sufficient functional hypertrophy response after portal vein embolization. Sixty-three patients who underwent preoperative portal vein embolization and computed tomography imaging were included. Hepatobiliary scintigraphy was performed to determine pre-portal vein embolization and post-portal vein embolization future remnant liver function. Receiver operator characteristic analysis of pre-portal vein embolization future remnant liver function was performed to identify patients who would meet the post-portal vein embolization cutoff value for sufficient function (ie, 2.7%/min/m 2 ). Mean pre-portal vein embolization future remnant liver function was 1.80% ± 0.45%/min/m 2 and increased to 2.89% ± 0.97%/min/m 2 post-portal vein embolization. Receiver operator characteristic analysis in 33 patients who did not receive chemotherapy revealed that a pre-portal vein embolization future remnant liver function of ≥1.72%/min/m 2 was able to identify patients who would meet the safe future remnant liver function cutoff value 3 weeks after portal vein embolization (area under the curve = 0.820). The predictive value was less pronounced in 30 patients treated with neoadjuvant chemotherapy (area under the curve = 0.618). A total of 45 of 63 patients underwent liver resection, of whom 5 of 45 developed postoperative liver failure; 4 of 5 patients had a post-portal vein embolization future remnant liver function below the cutoff value for safe resection. When selecting patients for portal vein embolization, future remnant liver function assessed with hepatobiliary scintigraphy can be used as a predictor of insufficient functional hypertrophy after portal vein embolization, especially in nonchemotherapy patients. These patients are potential candidates for ALPPS. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. Crustal Structure of the Ionian Basin and Eastern Sicily Margin: Results From a Wide-Angle Seismic Survey

    NASA Astrophysics Data System (ADS)

    Dellong, David; Klingelhoefer, Frauke; Kopp, Heidrun; Graindorge, David; Margheriti, Lucia; Moretti, Milena; Murphy, Shane; Gutscher, Marc-Andre

    2018-03-01

    In the Ionian Sea (central Mediterranean) the slow convergence between Africa and Eurasia results in the formation of a narrow subduction zone. The nature of the crust of the subducting plate remains debated and could represent the last remnants of the Neo-Tethys ocean. The origin of the Ionian basin is also under discussion, especially concerning the rifting mechanisms as the Malta Escarpment could represent a remnant of this opening. This subduction retreats toward the south-east (motion occurring since the last 35 Ma) but is confined to the narrow Ionian basin. A major lateral slab tear fault is required to accommodate the slab roll-back. This fault is thought to propagate along the eastern Sicily margin but its precise location remains controversial. This study focuses on the deep crustal structure of the eastern Sicily margin and the Malta Escarpment. We present two two-dimensional P wave velocity models obtained from forward modeling of wide-angle seismic data acquired onboard the R/V Meteor during the DIONYSUS cruise in 2014. The results image an oceanic crust within the Ionian basin as well as the deep structure of the Malta Escarpment, which presents characteristics of a transform margin. A deep and asymmetrical sedimentary basin is imaged south of the Messina strait and seems to have opened between the Calabrian and Peloritan continental terranes. The interpretation of the velocity models suggests that the tear fault is located east of the Malta Escarpment, along the Alfeo fault system.

  5. Preservation of layered paleodeposits in high-latitude pedestal craters on Mars

    NASA Astrophysics Data System (ADS)

    Kadish, Seth J.; Head, James W.

    2011-06-01

    An outstanding question in Mars' climate history is whether or not pedestal craters represent the armored remnants of ice-rich paleodeposits. We address this question using new high-resolution images; in a survey of several hundred high-latitude pedestal craters, we have identified 12 examples in which visible and/or topographically expressed layers are exposed on the marginal scarp of the pedestal. One example, located on the south polar layered deposits, preserves ice-rich layers that have otherwise been completely removed from the polar cap. These observations provide empirical evidence that the pedestal crater formation mechanism is capable of armoring and preserving ice-rich layered paleodeposits. Although layered exposures have not yet been observed in mid-latitude pedestal craters, high-latitude instances of discontinuous, partially covered layers suggest that layers can be readily concealed, likely through mantling and/or mass wasting processes along the marginal scarp. This interpretation is supported by the observation that high-latitude pedestals with exposed layers along their margins are, on average, taller than mid-latitude examples, and have larger, steeper marginal scarps, which may help to maintain layer exposures. These observations favor the interpretation that mid- to high-latitude pedestal craters represent the armored remnants of ice- and dust-rich paleodeposits, which occurred transiently due to changes in the climate regime. Preservation of fine-scale layering of ice and dust at these latitudes implies that the climate change did not involve regional melting conditions.

  6. Chandra Observations and Models of the Mixed Morphology Supernova Remnant W44: Global Trends

    NASA Technical Reports Server (NTRS)

    Shelton, R. L.; Kuntz, K. D.; Petre, R.

    2004-01-01

    We report on the Chandra observations of the archetypical mixed morphology (or thermal composite) supernova remnant, W44. As with other mixed morphology remnants, W44's projected center is bright in thermal X-rays. It has an obvious radio shell, but no discernable X-ray shell. In addition, X-ray bright knots dot W44's image. The spectral analysis of the Chandra data show that the remnant s hot, bright projected center is metal-rich and that the bright knots are regions of comparatively elevated elemental abundances. Neon is among the affected elements, suggesting that ejecta contributes to the abundance trends. Furthermore, some of the emitting iron atoms appear to be underionized with respect to the other ions, providing the first potential X-ray evidence for dust destruction in a supernova remnant. We use the Chandra data to test the following explanations for W44's X-ray bright center: 1.) entropy mixing due to bulk mixing or thermal conduction, 2.) evaporation of swept up clouds, and 3.) a metallicity gradient, possibly due to dust destruction and ejecta enrichment. In these tests, we assume that the remnant has evolved beyond the adiabatic evolutionary stage, which explains the X-ray dimness of the shell. The entropy mixed model spectrum was tested against the Chandra spectrum for the remnant's projected center and found to be a good match. The evaporating clouds model was constrained by the finding that the ionization parameters of the bright knots are similar to those of the surrounding regions. While both the entropy mixed and the evaporating clouds models are known to predict centrally bright X-ray morphologies, their predictions fall short of the observed brightness gradient. The resulting brightness gap can be largely filled in by emission from the extra metals in and near the remnant's projected center. The preponderance of evidence (including that drawn from other studies) suggests that W44's remarkable morphology can be attributed to dust destruction and ejecta enrichment within an entropy mixed, adiabatic phase supernova remnant. The Chandra data prompts a new question - by what astrophysical mechanisms are the metals distributed so inhomogeneously in the supernova remnant.

  7. Dosimetry in differentiated thyroid carcinoma (12-1402R)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Minguez, Pablo; Genolla, Jose; Celeiro, Jose Javier

    2013-01-15

    Purpose: The aim of this study has been to perform a dosimetric study in the treatments of differentiated thyroid cancer (DTC) performed in our center in order to find a dose-effect correlation. Methods: Thirty patients treated for DTC with 3700 MBq of {sup 131}I have been included in this study. For reasons of radiological protection all of them spent two nights as inpatients. Dose rate at 1 m from all patients was measured approximately 20 and 44 h after the administration of the radioiodine and a whole body scan in the gamma camera was performed approximately 1 week later. Withmore » those measurements and by using a model of two compartments the activities in thyroid bed remnants and in the whole body were calculated as a function of time. The integration of both activities yields the corresponding cumulated activities. Absorbed doses to thyroid bed remnants and to the whole body can be calculated following the MIRDOSE method-that is, by multiplying the corresponding cumulated activities by the corresponding S factors. Results: The absorbed doses to thyroid bed remnants calculated in this study fall into a very wide range (13-1161 Gy) and showed the highest correlation factors with the following parameters: the absorbed dose rate to thyroid bed remnants, the cumulated activity in thyroid bed remnants, and the maximum radioiodine uptake in thyroid bed remnants. The absorbed doses to the whole body range from 0.12 to 0.23 Gy. The ablation was successful in all patients, and in spite of the wide range of absorbed doses to thyroid bed remnants obtained, no dose-effect correlation could be obtained. Conclusions: Facing DTC treatments from a dosimetric viewpoint in which a predosimetry to calculate the activity of {sup 131}I to be administered is performed is a subject difficult to handle. This statement is based on the fact that although a very wide range of absorbed doses to thyroid bed remnants was obtained (including several absorbed doses well below some dose thresholds previously published to achieve ablation of thyroid bed remnants), ablation of thyroid bed remnants was successful for all patients and therefore no dose-effect correlation could be determined.« less

  8. 30 Dor B - A supernova remnant in a star formation region

    NASA Technical Reports Server (NTRS)

    Chu, You-Hua; Kennicutt, Robert C., Jr.; Schommer, Robert A.; Laff, Joshua

    1992-01-01

    The supernova remnant 30 Dor B is embedded in an H II region around the OB association LH 99, and has been suggested to be a Crab-type remnant. To determine the spatial extent and kinematic properties of this supernova remnant, long-slit echelle observations were obtained in the H-alpha and forbidden N II lines, along with imaging Fabry-Perot observations in the H-alpha line. It is found that 30 Dor B is partially obscured by a dark cloud with which the supernova remnant also interacts. The size of 30 Dor B is much larger than previously thought, making it much older than the Crab Nebula. If the progenitor of the supernova was formed coevally with LH 99, then it would have been more massive than the O3 members of the OB association.

  9. Congenital esophageal stenosis owing to tracheobronchial remnants.

    PubMed

    Rebelo, Priscila Guyt; Ormonde, João Victor C; Ormonde Filho, João Baptista C

    2013-09-01

    OBJECTIVE To emphasize the need of an accurate diagnosis of congenital esophageal stenosis due to tracheobronchial remnants, since its treatment differs from other types of congenital narrowing. CASE DESCRIPTION Four cases of lower congenital esophageal stenosis due to tracheobronchial remnants, whose definitive diagnosis was made by histopathology. Except for the last case, in which a concomitant anti-reflux surgery was not performed, all had a favorable outcome after resection and anastomosis of the esophagus. COMMENTS The congenital esophageal stenosis is an intrinsic narrowing of the organ's wall associated with its structural malformation. The condition can be caused by tracheobronchial remnants, fibromuscular stenosis or membranous diaphragm and the first symptom is dysphagia after the introduction of solid food in the diet. The first-choice treatment to tracheobronchial remnants cases is the surgical resection and end-to-end anastomosis of the esophagus.

  10. Maximum Energies of Shock-Accelerated Electrons in Young Shell Supernova Remnants

    NASA Technical Reports Server (NTRS)

    Reynolds, Stephen P.; Keohane, Jonathan W.; White, Nicholas E. (Technical Monitor)

    1999-01-01

    Young supernova remnants (SNRs) are often assumed to be the source of cosmic rays up to energies approaching the slight steepening in the cosmic ray spectrum at around 1000 TeV, known as the "knee." We show that the observed X-ray emission of 14 radio-bright shell remnants, including all five historical shells, can be used to put limits on E(sub max), the energy at which the electron energy distribution must steepen from its slope at radio-emitting energies. Most of the remnants show thermal spectra, so any synchrotron component must fall below the observed X-ray fluxes. We obtain upper limits on E(sub max) by considering the most rapid physically plausible cutoff in the relativistic electron distribution, an exponential, which is as sharp or sharper than found in any more elaborate models. This maximally curved model then gives us the highest possible E(sub max) consistent with not exceeding observed X-rays. Our results are thus independent of particular models for the electron spectrum in SNRs. Assuming homogeneous emitting volumes with a constant magnetic field strength of 10 uG, no object could reach 1000 TeV, and only one, Kes 73, has an upper limit on E(sub max), above 100 TeV. All the other remnants have limits at or below 80 TeV. E(sub max) is probably set by the finite remnant lifetime rather than by synchrotron losses for remnants younger than a few thousand years, so that an observed electron steepening should be accompanied by steepening at the same energy for protons. More complicated, inhomogeneous models could allow higher values of E(sub max) in parts of the remnant, but the emission-weighted average value, that characteristic of typical electrons, should obey these limits. The young remnants are not expected to improve much over their remaining lives at producing the highest energy Galactic cosmic rays; if they cannot, this picture of cosmic-ray origin may need major alteration.

  11. APOC3 Loss-of-Function Mutations, Remnant Cholesterol, Low-Density Lipoprotein Cholesterol, and Cardiovascular Risk: Mediation- and Meta-Analyses of 137 895 Individuals.

    PubMed

    Wulff, Anders B; Nordestgaard, Børge G; Tybjærg-Hansen, Anne

    2018-03-01

    Loss-of-function mutations in APOC3 associate with low remnant cholesterol levels and low risk of ischemic vascular disease (IVD). Because some studies show an additional association with low levels of low-density lipoprotein cholesterol (LDL-C), low LDL-C may explain the low risk of IVD in APOC3 loss-of-function heterozygotes. We tested to what extent the low risk of IVD in APOC3 loss-of-function heterozygotes is mediated by low plasma remnant cholesterol and LDL-C. In APOC3 loss-of-function heterozygotes versus noncarriers, we first determined remnant cholesterol and LDL-C levels in meta-analyses of 137 895 individuals. Second, we determined whether the association with LDL-C was masked by lipid-lowering therapy. Finally, using mediation analysis, we determined the fraction of the low risk of IVD and ischemic heart disease mediated by remnant cholesterol and LDL-C. In meta-analyses, remnant cholesterol was 43% lower (95% confidence interval, 40%-47%), and LDL-C was 4% lower (1%-6%) in loss-of-function heterozygotes (n=776) versus noncarriers. In the general population, LDL-C was 3% lower in loss-of-function heterozygotes versus noncarriers, 4% lower when correcting for lipid-lowering therapy, and 3% lower in untreated individuals ( P values, 0.06-0.008). Remnant cholesterol mediated 37% of the observed 41% lower risk of IVD and 54% of the observed 36% lower risk of ischemic heart disease; corresponding values mediated by LDL-C were 1% and 2%. The low risk of IVD observed in APOC3 loss-of-function heterozygotes is mainly mediated by the associated low remnant cholesterol and not by low LDL-C. Furthermore, the contribution of LDL-C to IVD risk was not masked by lipid-lowering therapy. This suggests APOC3 and remnant cholesterol as important new targets for reducing cardiovascular risk. © 2018 American Heart Association, Inc.

  12. Bile reflux of the remnant stomach following Roux-en-Y gastric bypass: an etiology of chronic abdominal pain treated with remnant gastrectomy.

    PubMed

    Vella, Erika La; Hovorka, Zach; Yarbrough, Donald E; McQuitty, Elizabeth

    2017-08-01

    Bile reflux gastritis of the remnant stomach following Roux-en-Y gastric bypass (RYGB) causing chronic abdominal pain has not been reported. We report a series of symptomatic patients with remnant gastritis treated effectively with remnant gastrectomy (RG). The objective was to report our experience with bile reflux remnant gastritis after RYGB and our outcomes following RG. Community teaching hospital. All patients undergoing RG were retrospectively reviewed for presenting symptoms, diagnostic workup, pathology, complications, and symptom resolution. Nineteen patients underwent RG for bile reflux gastritis at a mean of 4.4 years (52.3 mo, range 8.5-124 mo) after RYGB. All patients were female and presented with pain, primarily epigastric (18/19; 95%), and described as burning (11/19; 58%), with 10 (53%) reporting nausea. Endoscopy was performed preoperatively on all patients with successful remnant inspection in 13 (68%), using push endoscopy (n = 10) or operative assist (n = 3), with 12 (of 13; 92%) biopsy-positive for reactive gastropathy. Seventeen (90%) completed a hepatobiliary scintigraphy scan with 100% positivity demonstrating bile reflux across the pylorus. Surgical approach was laparoscopic or robotic in 18 (95%) with a hospital length of stay of 2.7 days (range 0-12 d), with no major complications or readmissions. Pathology of the remnant confirmed reactive gastropathy in 90% (n = 17). Ninety percent of patients (n = 17) reported sustained symptom resolution, and 11% of patients (n = 2) remained symptomatic at last follow-up. We followed all patients for a mean of 6.6 years (1-194 mo). Bile reflux gastritis of the remnant stomach is a new consideration for chronic abdominal pain months to years following RYGB. Hepatobiliary scintigraphy imaging and endoscopic biopsy are highly suggestive. RG is safe and effective treatment. Copyright © 2017 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.

  13. A Comparative Animal Study of Tendon Grafts Healing After Remnant-Preserving Versus Conventional Anterior Cruciate Ligament Reconstruction

    PubMed Central

    Zhang, Lei; Jiang, Kan; Chai, Hao; Zhou, Mei; Bai, Jingping

    2016-01-01

    Background The aim of this study was to determine if anterior cruciate ligament (ACL) reconstruction by remnant preservation promotes cell proliferation, vascularization, proprioception recovery, and improved biomechanical properties of the tendon grafts. Material/Methods 75 New Zealand rabbits were randomly assigned into the control group (group A), conventional ACL reconstruction group (group B), ACL reconstruction using remnant preservation and graft through remnant sleeve technique group (group C), and ACL reconstruction using remnant preservation and remnant tensioning technique group (group D). The remnant and healing of tendon grafts in groups C and D were observed at 3, 6, and 12 weeks after surgery, and the mRNA expression levels of VEGF, NT-3 and GAP-43 in ACL (group A) or tendon graft samples (groups B, C, and D) were determined by real-time PCR. Tendon graft cell count, microvessel density (MVD), and proprioceptors were determined by H&E staining, CD34, and S-100 immunohistochemical staining. The biomechanical properties of the tendon graft at week 12 in groups B, C, and D were examined by using a tensile strength test. Results Remnant and tendon grafts were not healed at 3, 6, and 12 weeks after the operation in groups C and D. VEGF, NT-3, and GAP-43 mRNA expressions in groups B, C, and D were higher than those in group A (P<0.05), but no significant difference was observed between groups B, C, and D (P>0.05). Furthermore, tendon graft cell count, MVD, proprioception, and biomechanical properties showed no significant differences (P>0.05) among groups B, C, and D at various time points. Conclusions There was no significant difference in cell proliferation, vascularization, proprioception recovery, or biomechanical properties of the tendon grafts between remnant-preserving and conventional ACL reconstruction methods. PMID:27669454

  14. Mucocele of the cystic duct remnant after orthotopic liver transplant: a problem revisited.

    PubMed

    Chatterjee, Suvadip; Das, Debasish; Hudson, Mark; Bassendine, Margaret Fiona; Scott, John; Oppong, Kofi Ernest; Sen, Gourab; French, Jeremy J

    2011-06-01

    Mucocele of the cystic duct remnant is an uncommon hepatobiliary complication of a liver transplant. Current practice usually involves either excising the cystic duct, or incorporating the distal end of the transected cystic duct into the suture line of the biliary anastomosis to ensure drainage. We report a patient who developed cystic duct remnant mucocele after the latter approach was adopted. We believe that this is likely related to delayed anastomotic stricturing, which prevented draining from the remnant cystic duct. We also discuss the incidence, pathology, investigations, and treatment of this condition.

  15. Precursor uptake assays and metabolic analyses in isolated tomato fruit chromoplasts

    PubMed Central

    2012-01-01

    Background Carotenoids are the most widespread group of pigments found in nature. In addition to their role in the physiology of the plant, carotenoids also have nutritional relevance as their incorporation in the human diet provides health benefits. In non-photosynthetic tissues, carotenoids are synthesized and stored in specialized plastids called chromoplasts. At present very little is known about the origin of the metabolic precursors and cofactors required to sustain the high rate of carotenoid biosynthesis in these plastids. Recent proteomic data have revealed a number of biochemical and metabolic processes potentially operating in fruit chromoplasts. However, considering that chloroplast to chromoplast differentiation is a very rapid process during fruit ripening, there is the possibility that some of the proteins identified in the proteomic analysis could represent remnants no longer having a functional role in chromoplasts. Therefore, experimental validation is necessary to prove whether these predicted processes are actually operative in chromoplasts. Results A method has been established for high-yield purification of tomato fruit chromoplasts suitable for metabolic studies. Radiolabeled precursors were efficiently incorporated and further metabolized in isolated chromoplast. Analysis of labeled lipophilic compounds has revealed that lipid biosynthesis is a very efficient process in chromoplasts, while the relatively low incorporation levels found in carotenoids suggest that lipid production may represent a competing pathway for carotenoid biosynthesis. Malate and pyruvate are efficiently converted into acetyl-CoA, in agreement with the active operation of the malic enzyme and the pyruvate dehydrogenase complex in the chromoplast. Our results have also shown that isolated chromoplasts can actively sustain anabolic processes without the exogenous supply of ATP, thus suggesting that these organelles may generate this energetic cofactor in an autonomous way. Conclusions We have set up a method for high yield purification of intact tomato fruit chromoplasts suitable for precursor uptake assays and metabolic analyses. Using targeted radiolabeled precursors we have been able to unravel novel biochemical and metabolic aspects related with carotenoid and lipid biosynthesis in tomato fruit chromoplasts. The reported chromoplast system could represent a valuable platform to address the validation and characterization of functional processes predicted from recent transcriptomic and proteomic data. PMID:22243738

  16. Precursor uptake assays and metabolic analyses in isolated tomato fruit chromoplasts.

    PubMed

    Angaman, Djédoux Maxime; Petrizzo, Rocco; Hernández-Gras, Francesc; Romero-Segura, Carmen; Pateraki, Irene; Busquets, Montserrat; Boronat, Albert

    2012-01-13

    Carotenoids are the most widespread group of pigments found in nature. In addition to their role in the physiology of the plant, carotenoids also have nutritional relevance as their incorporation in the human diet provides health benefits. In non-photosynthetic tissues, carotenoids are synthesized and stored in specialized plastids called chromoplasts. At present very little is known about the origin of the metabolic precursors and cofactors required to sustain the high rate of carotenoid biosynthesis in these plastids. Recent proteomic data have revealed a number of biochemical and metabolic processes potentially operating in fruit chromoplasts. However, considering that chloroplast to chromoplast differentiation is a very rapid process during fruit ripening, there is the possibility that some of the proteins identified in the proteomic analysis could represent remnants no longer having a functional role in chromoplasts. Therefore, experimental validation is necessary to prove whether these predicted processes are actually operative in chromoplasts. A method has been established for high-yield purification of tomato fruit chromoplasts suitable for metabolic studies. Radiolabeled precursors were efficiently incorporated and further metabolized in isolated chromoplast. Analysis of labeled lipophilic compounds has revealed that lipid biosynthesis is a very efficient process in chromoplasts, while the relatively low incorporation levels found in carotenoids suggest that lipid production may represent a competing pathway for carotenoid biosynthesis. Malate and pyruvate are efficiently converted into acetyl-CoA, in agreement with the active operation of the malic enzyme and the pyruvate dehydrogenase complex in the chromoplast. Our results have also shown that isolated chromoplasts can actively sustain anabolic processes without the exogenous supply of ATP, thus suggesting that these organelles may generate this energetic cofactor in an autonomous way. We have set up a method for high yield purification of intact tomato fruit chromoplasts suitable for precursor uptake assays and metabolic analyses. Using targeted radiolabeled precursors we have been able to unravel novel biochemical and metabolic aspects related with carotenoid and lipid biosynthesis in tomato fruit chromoplasts. The reported chromoplast system could represent a valuable platform to address the validation and characterization of functional processes predicted from recent transcriptomic and proteomic data.

  17. Orchid Bee (Apidae: Euglossini) Communities in Atlantic Forest Remnants and Restored Areas in Paraná State, Brazil.

    PubMed

    Ferronato, M C F; Giangarelli, D C; Mazzaro, D; Uemura, N; Sofia, S H

    2018-06-01

    In this study, we compare orchid bee communities surveyed in four forest remnants of the Atlantic Forest and four reforested areas characterized by seasonal semi-deciduous forest vegetation in different successional stages (mature and secondary vegetation), located in southern Brazil. The sizes of forest remnants and reforested areas varied from 32.1 to 583.9 ha and from 11.3 to 33.3 ha, respectively. All reforested areas were located near one forest remnant. During samplings, totaling nine per study area, euglossine males were attracted to eight scent baits and captured with bait trap and entomological nets. Each forest remnant and its respective reforested area were sampled simultaneously by two collectors. We collected 435 males belonging to nine species of orchid bees distributed in four genera. The number of individuals and species did not differ significantly between different areas, except for a reforested area (size 33.3 ha), which was located far from its respective forest remnant. Our findings also revealed an apparent association between an orchid bee species (Euglossa annectans Dressler 1982) and the most preserved area surveyed in our study, suggesting that this bee is a potential indicator of good habitat quality in recuperating or preserved areas. Our results suggest that reforested habitats located near forest remnants have a higher probability of having reinstated their euglossine communities.

  18. ROSAT PSPC and HRI Observations of Supernova Remnant G292.0+1.8

    NASA Technical Reports Server (NTRS)

    Hughes, John P.

    1999-01-01

    The supernova remnant G292.0+1.8 was observed by the ROSAT PSPC for 18 ksec as part of this grant. Considerable effort was put into the analysis of the PSPC spectra. The major work went into nonequilibrium ionization joint spectral fits with the Einstein SSS and EXOSAT ME data which indicated that the two spatial regions of this remnant (a central bar and a plateau region covering a larger extent) had similar abundances, but different excitation conditions (temperature and ionization state), an important conclusion, if true. Unfortunately as this work was being finished, new ASCA data revealed the presence of a previously unknown, spectrally hard X-ray source near the center of the remnant which contaminated the SSS and ME data and as a consequence made our detailed spectral analysis done up until then un-publishable. We searched for evidence of this hard source in the PSPC data both spectrally and using timing searches (for a pulsar), but found nothing significant. ROSAT HRI data were also obtained on this remnant. These data were compared to the Einstein HRI data to search for evidence of spectral variations with position and possible expansion of the X-ray remnant. One feature in the remnant appears to have changed in brightness although it is not clear what is the cause of the change. No evidence for the hard ASCA source was apparent in the HRI data.

  19. Chandra Detection of a Pulsar Wind Nebula Associated With Supernova Remnant 3C 396

    NASA Technical Reports Server (NTRS)

    Olbert, C. M.; Keohane, J. W.; Arnaud, K. A.; Dyer, K. K.; Reynolds, S. P.; Safi-Harb, S.

    2003-01-01

    We present a 100 ks observation of the Galactic supernova remnant 3C396 (G39.2-0.3) with the Chandra X-Ray Observatory that we compare to a 20cm map of the remnant from the Very Large Array. In the Chandra images, a nonthermal nebula containing an embedded pointlike source is apparent near the center of the remnant which we interpret as a synchrotron pulsar wind nebula surrounding a yet undetected pulsar. From the 2-10 keV spectrum for the nebula (N(sub H) = 5.3 plus or minus 0.9 x 10(exp 22) per square centimeter, GAMMA =1.5 plus or minus 0.3) we derive an unabsorbed x-ray flux of S(sub z)=1.62 x 10(exp -12) erg per square centimeter per second, and from this we estimate the spin-down power of the neutron star to be E(sup dot) = 7.2 x 10(exp 36) ergs per second. The central nebula is morphologically complex, showing bent, extended structure. The radio and X-ray shells of the remnant correlate poorly on large scales, particularly on the eastern half of the remnant, which appears very faint in X-ray images. At both radio and X-ray wavelengths the western half of the remnant is substantially brighter than the east.

  20. Morphologic evaluation of remnant anterior cruciate ligament bundles after injury with three-dimensional computed tomography.

    PubMed

    Adachi, Nobuo; Ochi, Mitsuo; Takazawa, Kobun; Ishifuro, Minoru; Deie, Masataka; Nakamae, Atsuo; Kamei, Goki

    2016-01-01

    This study aimed to investigate the morphological patterns of remnant anterior cruciate ligament bundles after injury (ACL remnant) on three-dimensional computed tomography (3DCT) and compare them with those on arthroscopy. Sixty-three patients (33 males and 30 females; mean age 25.2 ± 10.1 years) who had undergone primary ACL reconstruction between March 2011 and December 2012 were included in this study. The average durations between traumas and 3DCT and between 3DCT and surgery were 101.7 ± 87.2 and 38.2 ± 38.7 days, respectively. ACL remnants were classified into four morphological patterns on 3DCT. 3DCT findings were compared with arthroscopic findings with and without probing. The morphological patterns of the ACL remnants on 3DCT were well matched with those on arthroscopy without probing (the concordance rate was 77.8%). However, the concordance rate was reduced to 49.2% when arthroscopic probing was used to confirm the femoral attachment of ACL remnants (p ≤ 0.05). This study demonstrates that the morphological patterns of ACL remnants on 3DCT were well matched with those on arthroscopy without probing. Therefore, the technique can be useful for preoperative planning of the ACL reconstruction or informed consent to the patients. However, for definitive diagnosis, arthroscopic probing is required. IV.

  1. Remnant radio-loud AGN in the Herschel-ATLAS field

    NASA Astrophysics Data System (ADS)

    Mahatma, V. H.; Hardcastle, M. J.; Williams, W. L.; Brienza, M.; Brüggen, M.; Croston, J. H.; Gurkan, G.; Harwood, J. J.; Kunert-Bajraszewska, M.; Morganti, R.; Röttgering, H. J. A.; Shimwell, T. W.; Tasse, C.

    2018-04-01

    Only a small fraction of observed active galactic nuclei (AGN) display large-scale radio emission associated with jets, yet these radio-loud AGN have become increasingly important in models of galaxy evolution. In determining the dynamics and energetics of the radio sources over cosmic time, a key question concerns what happens when their jets switch off. The resulting `remnant' radio-loud AGN have been surprisingly evasive in past radio surveys, and therefore statistical information on the population of radio-loud AGN in their dying phase is limited. In this paper, with the recent developments of Low-Frequency Array (LOFAR) and the Very Large Array, we are able to provide a systematically selected sample of remnant radio-loud AGN in the Herschel-ATLAS field. Using a simple core-detection method, we constrain the upper limit on the fraction of remnants in our radio-loud AGN sample to 9 per cent, implying that the extended lobe emission fades rapidly once the core/jets turn off. We also find that our remnant sample has a wide range of spectral indices (-1.5≤slant α ^{1400}_{150}≤slant -0.5), confirming that the lobes of some remnants may possess flat spectra at low frequencies just as active sources do. We suggest that, even with the unprecedented sensitivity of LOFAR, our sample may still only contain the youngest of the remnant population.

  2. Composition of microbial communities in aerosol, snow and ice samples from remote glaciated areas (Antarctica, Alps, Andes)

    NASA Astrophysics Data System (ADS)

    Elster, J.; Delmas, R. J.; Petit, J.-R.; Řeháková, K.

    2007-06-01

    Taxonomical and ecological analyses were performed on micro-autotrophs (cyanobacteria and algae together with remnants of diatom valves), micro-fungi (hyphae and spores), bacteria (rod, cocci and red clusters), yeast, and plant pollen extracted from various samples: Alps snow (Mt. Blank area), Andean snow (Illimani, Bolivia), Antarctic aerosol filters (Dumont d'Urville, Terre Adélie), and Antarctic inland ice (Terre Adélie). Three methods for ice and snow sample's pre-concentration were tested (filtration, centrifugation and lyophilisation). Afterwards, cultivation methods for terrestrial, freshwater and marine microorganisms (micro-autotrophs and micro-fungi) were used in combination with liquid and solid media. The main goal of the study was to find out if micro-autotrophs are commonly transported by air masses, and later stored in snow and icecaps around the world. The most striking result of this study was the absence of culturable micro-autotrophs in all studied samples. However, an unusual culturable pigmented prokaryote was found in both alpine snow and aerosol samples. Analyses of many samples and proper statistical analyses (PCA, RDA- Monte Carlo permutation tests) showed that studied treatments highly significantly differ in both microbial community and biotic remnants composition F=9.33, p=0.001. In addition, GLM showed that studied treatments highly significantly differ in numbers of categories of microorganisms and remnants of biological material F=11.45, p=0.00005. The Antarctic aerosol samples were characterised by having red clusters of bacteria, the unusual prokaryote and yeasts. The high mountain snow from the Alps and Andes contained much more culturable heterotrophs. The unusual prokaryote was very abundant, as were coccoid bacteria, red clusters of bacteria, as well as yeasts. The Antarctic ice samples were quite different. These samples had higher numbers of rod bacteria and fungal hyphae. The microbial communities and biological remnants of analysed samples comprises two communities, without a sharp boundary between them: i) the first community includes ubiquitous organisms including contaminants, ii) the second community represents individuals frequently occurring in remote terrestrial cold or hot desert/semi-desert and/or marginal soil-snow-ice ecosystems.

  3. Exploring properties of high-density matter through remnants of neutron-star mergers

    NASA Astrophysics Data System (ADS)

    Bauswein, Andreas; Stergioulas, Nikolaos; Janka, Hans-Thomas

    2016-03-01

    Remnants of neutron-star mergers are essentially massive, hot, differentially rotating neutron stars, which are initially strongly oscillating. As such they represent a unique probe for high-density matter because the oscillations are detectable via gravitational-wave measurements and are strongly dependent on the equation of state. The impact of the equation of state for instance is apparent in the frequency of the dominant oscillation mode of the remnant. For a fixed total binary mass a tight relation between the dominant postmerger oscillation frequency and the radii of nonrotating neutron stars exists. Inferring observationally the dominant postmerger frequency thus determines neutron star radii with high accuracy of the order of a few hundred meters. By considering symmetric and asymmetric binaries of the same chirp mass, we show that the knowledge of the binary mass ratio is not critical for this kind of radius measurements. We perform simulations which show that initial intrinsic neutron star rotation is unlikely to affect this method of constraining the high-density equation of state. We also summarize different possibilities about how the postmerger gravitational-wave emission can be employed to deduce the maximum mass of nonrotating neutron stars. We clarify the nature of the three most prominent features of the postmerger gravitational-wave spectrum and argue that the merger remnant can be considered to be a single, isolated, self-gravitating object that can be described by concepts of asteroseismology. We sketch how the consideration of the strength of secondary gravitational-wave peaks leads to a classification scheme of the gravitational-wave emission and postmerger dynamics. The understanding of the different mechanisms shaping the gravitational-wave signal yields a physically motivated analytic model of the gravitational-wave emission, which may form the basis for template-based gravitational-wave data analysis. We explore the observational consequences of a scenario of two families of compact stars including hadronic and quark matter stars. We find that this scenario leaves a distinctive imprint on the postmerger gravitational-wave signal. In particular, a strong discontinuity in the dominant postmerger frequency as function of the total mass will be a strong indication for two families of compact stars.

  4. Analysis of the efficacy of portal vein embolization for patients with extensive liver malignancy and very low future liver remnant volume, including a comparison with the associating liver partition with portal vein ligation for staged hepatectomy approach.

    PubMed

    Shindoh, Junichi; Vauthey, Jean-Nicolas; Zimmitti, Giuzeppe; Curley, Steven A; Huang, Steven Y; Mahvash, Armeen; Gupta, Sanjay; Wallace, Michael J; Aloia, Thomas A

    2013-07-01

    The primary reported indication for the associating liver partition with portal vein ligation for staged hepatectomy (ALPPS) technique is in patients with very low future liver remnant volumes. Given the elevated incidence of major morbidity (40%) and liver-related mortality (12%) with ALPPS, we sought to determine the safety and efficacy of percutaneous portal vein embolization (PVE) in a similar patient population. Tumor resectability and morbidity and mortality rates were reviewed for 144 consecutive liver tumor patients with future liver remnant to body weight ratios (LR/BW) less than 0.5%. All patients were referred for preoperative percutaneous right plus segment IV PVE using embolic microspheres, with planned reassessment of the LR/BW 30 days after PVE. Post-PVE outcomes were compared with reported outcomes for ALPPS. Percutaneous PVE was successfully performed in 141 of the 144 study patients (97.9%). Adequate regeneration was observed in 139 patients (98.5%) with median post-PVE LR/BW rising from 0.33% to 0.52% (p < 0.0001), representing a per-patient median regeneration rate of 62% (range 0.3% to 379%). In total, 104 patients underwent extended right hepatectomy (n = 102) or right hepatectomy (n = 2). The remaining 40 patients (27.8%) were not resectable due to short-interval disease progression (27 patients, 18.5%), insufficient liver regeneration (5 patients, 3.5%), and medical comorbidities (8 patients, 5.6%). After resection, the following outcomes were observed: major morbidity: 33.0% (34 of 104), liver insufficiency: 12.5% (13 of 104), and 90-day liver-related mortality: 5.8% (6 of 104). These oncologic and technical results compare favorably with those of ALPPS. Based on its ability to select oncologically resectable patients and superior safety and efficacy profiles, percutaneous right + segment IV PVE and interval surgery remains the standard of care for patients with very low future liver remnant volumes. Copyright © 2013 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

  5. Survival and surgical outcomes of cardiac cancer of the remnant stomach in comparison with primary cardiac cancer

    PubMed Central

    2014-01-01

    Background Although cardiac cancer of the remnant stomach and primary cardiac cancer both occur in the same position, their clinical characteristics and outcomes have not been compared previously. The objective of this study was designed to evaluate the prognosis of cardiac cancer of the remnant stomach in comparison with primary cardiac cancer. Methods In this retrospective comparative study, clinical data and prognosis were compared in 48 patients with cardiac cancer of the remnant stomach and 96 patients with primary cardiac cancer who underwent radical resection from January 1995 to June 2007. Clinicopathologic characteristics, survival times, mortality, and complications were analyzed. Results The 5-year survival rate was significantly higher in patients with primary cardiac cancer than in those with cardiac cancer of the remnant stomach (28.4% vs. 16.7%, P = 0.035). Serosal invasion, lymph node metastasis and tumor location were independent prognostic factors for survival. Subgroup analysis, however, showed similar survival rates in patients with primary cardiac cancer and cardiac cancer of the remnant stomach without serosal invasion (25.0% vs. 43.8%, P = 0.214) and without lymph node metastasis (25.0% vs. 38.8%, P = 0.255), as well as similar complication rates (20.8% vs. 11.5%, P = 0.138). Conclusion Although the survival rates after radical resection in patients with cardiac cancer of the remnant stomach were poorer than in those with primary cardiac cancer, they were similar in survival rates when patients without serosal invasion or lymph node metastasis. Therefore, early detection is an important way to improve overall survival in cardiac cancer of the remnant stomach. PMID:24468299

  6. A New Suggestion for the Radiation Target Volume After a Subtotal Gastrectomy in Patients With Stomach Cancer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nam, Heerim; Lim, Do Hoon; Kim, Sung

    2008-06-01

    Purpose: To compare treatment results between the use of two different radiation fields including and excluding remnant stomach and suggest new target volumes excluding remnant stomach after subtotal gastrectomy (STG) in patients with stomach cancer. Methods and Materials: We retrospectively analyzed 291 patients treated with adjuvant chemoradiotherapy after STG and D2 dissection at the Samsung Medical Center, Seoul, South Korea. Eighty-three patients registered from 1995 to 1997 underwent irradiation according to the INT 0116 protocol that recommended the inclusion of remnant stomach within the target volume (Group A). After this period, we excluded remnant stomach from the target volume formore » 208 patients (Group B). Median follow-up was 67 months. Results: Treatment failure developed in 93 patients (32.0%). Local and regional recurrence rates for Group A vs. Group B were 10.8% vs. 5.3% (p = not significant) and 9.6% vs. 6.3% (p = not significant), and recurrence rates for remnant stomach were 7.2% vs. 1.4% (p = 0.018), respectively. Overall and disease-free survival rates were not different between the two groups. Grade 3 or 4 vomiting and diarrhea developed more frequently in Group A than Group B (4.8% vs. 1.4% and 6.0% vs. 1.9%, respectively; p = 0.012; p < 0.001). Conclusion: Exclusion of remnant stomach from the radiation field had no effect on failure rates or survival, and a low complication rate occurred in patients treated excluding remnant stomach. We suggest that remnant stomach be excluded from the radiation target volume for patients with stomach cancer who undergo STG and D2 dissection.« less

  7. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Su, Yang; Fang, Min; Yang, Ji

    We have carried out {sup 12}CO, {sup 13}CO, and C{sup 18}O observations toward the mixed morphology supernova remnant (SNR) IC 443. The observations cover a 1.°5 × 1.°5 area and allow us to investigate the overall molecular environment of the remnant. Some northern and northeastern partial shell structure of CO gas is around the remnant. One of the partial shells, about 5' extending beyond the northeastern border of the remnant's bright radio shell, seems to just confine the faint radio halo. On the other hand, some faint CO clumps can be discerned along the eastern boundary of the faint remnant'smore » radio halo. Connecting the eastern CO clumps, the northeastern partial shell structures, and the northern CO partial shell, we can see that a half molecular ring structure appears to surround the remnant. The LSR velocity of the half-ring structure is in the range of –5 km s{sup –1} to –2 km s{sup –1}, which is consistent with that of the –4 km s{sup –1} molecular clouds. We suggest that the half-ring structure of the CO emission at V {sub LSR} ∼ –4 km s{sup –1} is associated with the SNR. The structures are possibly swept up by the stellar winds of SNR IC 443's massive progenitor. Based on the Wide-field Infrared Survey Explorer and the Two Micron All Sky Survey near-IR database, 62 young stellar object (YSO) candidates are selected within the radio halo of the remnant. These YSO candidates concentrated along the boundary of the remnant's bright radio shell are likely to be triggered by the stellar winds from the massive progenitor of SNR IC 443.« less

  8. Supernova Remnant Kes 17: An Efficient Cosmic Ray Accelerator inside a Molecular Cloud

    NASA Astrophysics Data System (ADS)

    Gelfand, Joseph D.; Castro, Daniel; Slane, Patrick O.; Temim, Tea; Hughes, John P.; Rakowski, Cara

    2013-11-01

    The supernova remnant Kes 17 (SNR G304.6+0.1) is one of a few but growing number of remnants detected across the electromagnetic spectrum. In this paper, we analyze recent radio, X-ray, and γ-ray observations of this object, determining that efficient cosmic ray acceleration is required to explain its broadband non-thermal spectrum. These observations also suggest that Kes 17 is expanding inside a molecular cloud, though our determination of its age depends on whether thermal conduction or clump evaporation is primarily responsible for its center-filled thermal X-ray morphology. Evidence for efficient cosmic ray acceleration in Kes 17 supports recent theoretical work concluding that the strong magnetic field, turbulence, and clumpy nature of molecular clouds enhance cosmic ray production in supernova remnants. While additional observations are needed to confirm this interpretation, further study of Kes 17 is important for understanding how cosmic rays are accelerated in supernova remnants.

  9. Analyzing Data Remnant Remains on User Devices to Determine Probative Artifacts in Cloud Environment.

    PubMed

    Ahmed, Abdulghani Ali; Xue Li, Chua

    2018-01-01

    Cloud storage service allows users to store their data online, so that they can remotely access, maintain, manage, and back up data from anywhere via the Internet. Although helpful, this storage creates a challenge to digital forensic investigators and practitioners in collecting, identifying, acquiring, and preserving evidential data. This study proposes an investigation scheme for analyzing data remnants and determining probative artifacts in a cloud environment. Using pCloud as a case study, this research collected the data remnants available on end-user device storage following the storing, uploading, and accessing of data in the cloud storage. Data remnants are collected from several sources, including client software files, directory listing, prefetch, registry, network PCAP, browser, and memory and link files. Results demonstrate that the collected remnants data are beneficial in determining a sufficient number of artifacts about the investigated cybercrime. © 2017 American Academy of Forensic Sciences.

  10. The nature of the Vela X-ray ``jet". The Rayleigh-Taylor instability and the origin of filamentary structures in the Vela supernova remnant

    NASA Astrophysics Data System (ADS)

    Gvaramadze, Vasilii

    1999-12-01

    The nature of the Vela X-ray ``jet", recently discovered by Markwardt & Ögelman (1995), is examined. It is suggested that the ``jet" arises along the interface of domelike deformations of the Rayleigh-Taylor unstable shell of the Vela supernova remnant; thereby the ``jet" is interpreted as a part of the general shell of the remnant. The origin of deformations as well as the general structure of the remnant are discussed in the framework of a model based on a cavity explosion of a supernova star. It is suggested that the shell deformations viewed at various angles appear as filamentary structures visible throughout the Vela supernova remnant at radio, optical, and X-ray wavelengths. A possible origin of the nebula of hard X-ray emission detected by Willmore et al. (1992) around the Vela pulsar is proposed.

  11. Congenital esophageal stenosis owing to tracheobronchial remnants

    PubMed Central

    Rebelo, Priscila Guyt; Ormonde, João Victor C.; Ormonde, João Baptista C.

    2013-01-01

    OBJECTIVE To emphasize the need of an accurate diagnosis of congenital esophageal stenosis due to tracheobronchial remnants, since its treatment differs from other types of congenital narrowing. CASE DESCRIPTION Four cases of lower congenital esophageal stenosis due to tracheobronchial remnants, whose definitive diagnosis was made by histopathology. Except for the last case, in which a concomitant anti-reflux surgery was not performed, all had a favorable outcome after resection and anastomosis of the esophagus. COMMENTS The congenital esophageal stenosis is an intrinsic narrowing of the organâ€(tm)s wall associated with its structural malformation. The condition can be caused by tracheobronchial remnants, fibromuscular stenosis or membranous diaphragm and the first symptom is dysphagia after the introduction of solid food in the diet. The first-choice treatment to tracheobronchial remnants cases is the surgical resection and end-to-end anastomosis of the esophagus. PMID:24142326

  12. Appendicoumbilical Fistula: A Rare Reason for Neonatal Umbilical Mass

    PubMed Central

    Cevik, M.; Boleken, M. E.; Kadıoglu, E.

    2011-01-01

    The normal umbilicus is a simple structure, but the intrauterine development of the umbilicus is highly complex. Neonatal umbilical mass anomalies usually represent failure of obliteration of the vitelline duct or the allantois which results in persistence of remnants, which can lead to a wide variety of disorders. In this paper, we present a case of an appendicoumbilical fistula in a neonate along with the differential diagnosis and management options. Embryologic explanation of the etiology was discussed with the possible association with different forms of malpositioning and rotation of the gut. PMID:21629815

  13. Appendicoumbilical fistula: a rare reason for neonatal umbilical mass.

    PubMed

    Cevik, M; Boleken, M E; Kadıoglu, E

    2011-01-01

    The normal umbilicus is a simple structure, but the intrauterine development of the umbilicus is highly complex. Neonatal umbilical mass anomalies usually represent failure of obliteration of the vitelline duct or the allantois which results in persistence of remnants, which can lead to a wide variety of disorders. In this paper, we present a case of an appendicoumbilical fistula in a neonate along with the differential diagnosis and management options. Embryologic explanation of the etiology was discussed with the possible association with different forms of malpositioning and rotation of the gut.

  14. Rathke's pouch remnant and its regression process in the prenatal period.

    PubMed

    Cho, Kwang Ho; Chang, Hyuk; Yamamoto, Masahito; Abe, Hiroshi; Rodríguez-Vázquez, Jose Francisco; Murakami, Gen; Katori, Yukio

    2013-05-01

    During ontogeny, part of Rathke's pouch, a physiologically superior pouching of the stomodeal ectoderm, may remain, forming the usual anomaly known as Rathke's cleft cyst. More rarely, however, the entire pouch (i.e., the craniopharyngeal canal) remains, resulting in transsphenoidal meningoencephalocele. This study is aimed to provide a better understanding of the pathogenesis. We histologically evaluated the inferior protrusion of the putative hypophysial fossa in 35 embryonic and fetal heads, respectively (15 at 5-8 weeks and 20 at 12-16 weeks of gestation). In 3 of the 35 specimens, we observed a complete cleft originating from the adenohypophysis, passing through the sphenoid and connecting with the pharyngeal epithelium or pharyngobasilar fascia. In another 18 specimens, we observed a duct-like structure protruding from the fossa and ending in the sphenoid. The sellar protrusion contained vein-like structures and debris of red blood cells. The protrusion was located on the anterior or anterosuperior side of the notochord. No ossification center was observed around the sellar region of the embryos. Although ossification occurred in 12 of the 20 fetuses, nine of the latter showed no evidence of cleft or protrusion, indicating that the incidence of Rathke's pouch remnant was lower in the fetuses (11/20) than in the embryos (11/15). Rathke's pouch may be closed by ossification of the sphenoid, but increased cell proliferation and/or large amounts of degenerated veins may provide a structure resistant to the mechanical pressure caused by ossification.

  15. DEM L241, A SUPERNOVA REMNANT CONTAINING A HIGH-MASS X-RAY BINARY

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Seward, F. D.; Charles, P. A.; Foster, D. L.

    2012-11-10

    A Chandra observation of the Large Magellanic Cloud supernova remnant DEM L241 reveals an interior unresolved source which is probably an accretion-powered binary. The optical counterpart is an O5III(f) star making this a high-mass X-ray binary with an orbital period likely to be of the order of tens of days. Emission from the remnant interior is thermal and spectral information is used to derive density and mass of the hot material. Elongation of the remnant is unusual and possible causes of this are discussed. The precursor star probably had mass >25 M {sub Sun}.

  16. A CHANDRA OBSERVATION OF SNR 0540 - 697

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Seward, F. D.; Williams, R. M.; Chu, Y.-H.

    2010-07-15

    This paper describes a Chandra observation of SNR 0540 - 697 within the H II complex N159 in the Large Magellanic Cloud (LMC). Scattering from the nearby bright source LMC X-1, which obscures the western edge of the remnant, has been removed. Larger than previously believed, the 2.'0 x 2.'8 remnant is defined by optical filaments and two lobes of X-ray emission. A band of intervening material absorbs X-rays from the central part of the remnant. The N Lobe of the remnant is relatively bright and well defined, while emission from the S Lobe is much weaker. There is structuremore » within the N Lobe but no clear X-ray emission from an outer shell indicating a shock in the interstellar medium. The X-ray spectrum is thermal with emission lines from Fe, Mg, and Si. The observed temperature and luminosity of the hot gas are 0.6 keV and 6 x 10{sup 35} erg s{sup -1}, respectively. These are consistent with characteristics expected for older remnants. There is also diffuse thermal X-ray emission north of N159 extending into N160, evidence for a larger remnant or bubble.« less

  17. Landscape genomics reveals altered genome wide diversity within revegetated stands of Eucalyptus microcarpa (Grey Box).

    PubMed

    Jordan, Rebecca; Dillon, Shannon K; Prober, Suzanne M; Hoffmann, Ary A

    2016-12-01

    In order to contribute to evolutionary resilience and adaptive potential in highly modified landscapes, revegetated areas should ideally reflect levels of genetic diversity within and across natural stands. Landscape genomic analyses enable such diversity patterns to be characterized at genome and chromosomal levels. Landscape-wide patterns of genomic diversity were assessed in Eucalyptus microcarpa, a dominant tree species widely used in revegetation in Southeastern Australia. Trees from small and large patches within large remnants, small isolated remnants and revegetation sites were assessed across the now highly fragmented distribution of this species using the DArTseq genomic approach. Genomic diversity was similar within all three types of remnant patches analysed, although often significantly but only slightly lower in revegetation sites compared with natural remnants. Differences in diversity between stand types varied across chromosomes. Genomic differentiation was higher between small, isolated remnants, and among revegetated sites compared with natural stands. We conclude that small remnants and revegetated sites of our E. microcarpa samples largely but not completely capture patterns in genomic diversity across the landscape. Genomic approaches provide a powerful tool for assessing restoration efforts across the landscape. © 2016 The Authors. New Phytologist © 2016 New Phytologist Trust.

  18. Normalization of pH level and gastric mucosa after eradication of H. pylori in the remnant stomach.

    PubMed

    Kato, Shunji; Matsukura, Norio; Matsuda, Noriko; Tsuchiya, Shinichi; Naito, Zenya; Tajiri, Takashi

    2008-12-01

    The Updated Sydney System (USS) is used to evaluate chronic gastritis and chronic atrophic gastritis (CAG) due to H. pylori infection. Here, we investigated USS scores and gastric juice pH levels in H. pylori infection-positive or -eradicated patients with remnant stomach after surgery. Gastric juice pH levels were measured using pH test-tape in 197 patients (112 H. pylori-positive and 85 H. pylori-negative after eradication) who had undergone distal gastrectomy and conventional H. pylori eradication therapy. In H. pylori infection-positive remnant stomach cases, gastric juice pH showed a reverse correlation with pepsinogen I/II ratio, and H. pylori infection-negative patients following eradication showed associations with the degree of atrophy and intestinal metaplasia at both the anastomosis and in the corpus. Further, pH levels in these patients were normalized time depending after the eradication in the remnant stomach. Eradication therapy for the remnant stomach contributes to the possible improvement of stomach conditions by controlling the pH level of gastric juice. This effect will be protective against the risk of secondary stomach carcinogenesis in the remnant stomach.

  19. Knowledge environments representing molecular entities for the virtual physiological human.

    PubMed

    Hofmann-Apitius, Martin; Fluck, Juliane; Furlong, Laura; Fornes, Oriol; Kolárik, Corinna; Hanser, Susanne; Boeker, Martin; Schulz, Stefan; Sanz, Ferran; Klinger, Roman; Mevissen, Theo; Gattermayer, Tobias; Oliva, Baldo; Friedrich, Christoph M

    2008-09-13

    In essence, the virtual physiological human (VPH) is a multiscale representation of human physiology spanning from the molecular level via cellular processes and multicellular organization of tissues to complex organ function. The different scales of the VPH deal with different entities, relationships and processes, and in consequence the models used to describe and simulate biological functions vary significantly. Here, we describe methods and strategies to generate knowledge environments representing molecular entities that can be used for modelling the molecular scale of the VPH. Our strategy to generate knowledge environments representing molecular entities is based on the combination of information extraction from scientific text and the integration of information from biomolecular databases. We introduce @neuLink, a first prototype of an automatically generated, disease-specific knowledge environment combining biomolecular, chemical, genetic and medical information. Finally, we provide a perspective for the future implementation and use of knowledge environments representing molecular entities for the VPH.

  20. The remnants of restinga habitats in the brazilian Atlantic Forest of Rio de Janeiro state, Brazil: habitat loss and risk of disappearance.

    PubMed

    Rocha, C F D; Bergallo, H G; Van Sluys, M; Alves, M A S; Jamel, C E

    2007-05-01

    "Restingas" (herbaceous/shrubby coastal sand-dune habitats) used to cover most of Rio de Janeiro State coast, and have suffered extensive degradation over the last five centuries. Using satellite images and field work, we identified the remaining restingas in the State, recording the factors that might cause their degradation. We used two mosaics of Landsat 7 scenes (spatial resolution 15 and 30 m) to map and evaluate preliminarly the remaining areas and conservation status. Each remnant area was checked in the field, degraded areas within it were mapped and subtracted from the remnants. We identified 21 restinga remnants totalling 105,285 ha. The largest and smallest restinga remnants were Jurubatiba (25,141 ha) and Itaipu (23 ha), respectively. We identified 14 causes of degradation. The most important were vegetation removal for housing developments, establishment of exotic plant species, change of original substrate, and selective removal of species of economic importance for the horticultural industry. All restingas had disturbed parts under strong pressure due to human activities. Due to intense habitat loss, and occurrence of endemic/threatened vertebrate species in restinga habitats, we strongly indicate the implementation of new conservation units to protect these fragile remnants. This habitat is steadily decreasing and most remnants lack legal protection. Therefore, under the current human pressure most of this unique habitat is likely to be lost from the State within the next few years.

  1. Black hole remnants and the information loss paradox

    NASA Astrophysics Data System (ADS)

    Chen, P.; Ong, Y. C.; Yeom, D.-h.

    2015-11-01

    Forty years after the discovery of Hawking radiation, its exact nature remains elusive. If Hawking radiation does not carry any information out from the ever shrinking black hole, it seems that unitarity is violated once the black hole completely evaporates. On the other hand, attempts to recover information via quantum entanglement lead to the firewall controversy. Amid the confusions, the possibility that black hole evaporation stops with a "remnant" has remained unpopular and is often dismissed due to some "undesired properties" of such an object. Nevertheless, as in any scientific debate, the pros and cons of any proposal must be carefully scrutinized. We fill in the void of the literature by providing a timely review of various types of black hole remnants, and provide some new thoughts regarding the challenges that black hole remnants face in the context of the information loss paradox and its latest incarnation, namely the firewall controversy. The importance of understanding the role of curvature singularity is also emphasized, after all there remains a possibility that the singularity cannot be cured even by quantum gravity. In this context a black hole remnant conveniently serves as a cosmic censor. We conclude that a remnant remains a possible end state of Hawking evaporation, and if it contains large interior geometry, may help to ameliorate the information loss paradox and the firewall controversy. We hope that this will raise some interests in the community to investigate remnants more critically but also more thoroughly.

  2. Angiographic and epidemiological characteristics associated with aneurysm remnants after microsurgical clipping

    PubMed Central

    Dellaretti, Marcos; da Silva Martins, Warley Carvalho; Dourado, Jules Carlos; Faglioni, Wilson; Quadros, Ricardo Souza; de Souza Moraes, Vítor Vieira; de Souza Filho, Carlos Batista Alves

    2017-01-01

    Background: Despite new techniques for the treatment of cerebral aneurysms, the percentage of aneurysm remnants after surgical intervention seems to be relatively constant. The objective of this study was to assess angiographic and epidemiological features associated with aneurysm remnants after microsurgical clipping. Methods: This study was conducted from February 2009 to August 2012 on a series of 90 patients with 105 aneurysms referred to the Santa Casa of Belo Horizonte who were surgically treated and angiographically controlled. Results: Surgical clipping was considered incomplete in 13.3% of the aneurysms. The mean age of cases with an aneurysm remnant was 57.5 years, whereas the mean age without aneurysm remnant was 49.7 years (P = 0.02). Aneurysm remnants were detected more frequently on the internal carotid artery, nevertheless, no statistically significant differences were verified when comparing the locations. Aneurysm size in the preoperative angiography verified that the mean size of aneurysms operated was 6.56 mm, such that in cases showing a postoperative remnant, the mean size was 9.7 mm and in cases with complete clipping it was 6.08 mm (P = 0.02). Postoperative angiography showed that, in cases with residual aneurysm, the number of clips used was higher – a mean of 1.8 for complete clipping and 3.1 for incomplete clipping (P < 0.001). Conclusions: Aneurysm size and patient age showed significant correlations with residual intracranial aneurysm. The mean number of clips used was higher in cases with incomplete occlusion. PMID:28904825

  3. A kinematic study of 0509-67.5, the second youngest supernova remnant in the Large Magellanic Cloud, and its astrophysical implications

    NASA Astrophysics Data System (ADS)

    Hovey, Luke

    2016-05-01

    Supernova remnants are the lasting interactions of shock waves that develop in the wake of supernovae. These remnants, especially those in our galaxy and our companion galaxies, allow us to study supernovae for thousands of years after the initial stellar explosions. Remnants that are formed from Ia supernovae, which are the explosions and complete annihilation of white dwarf stars, are of particular interest due to the explosions' value as standard candles in cosmological studies. The shock waves in these young supernova remnants offer an unparalleled look into the physical processes that take place there, especially since these shocks are often simpler to study than shocks with strong radiative components that are present in remnants that are formed from the core-collapse supernovae of massive stars. I will detail the work of my kinematic study of the second youngest remnant in the Large Magellanic Cloud, 0509--67.5, which has been confirmed to be the result of a Ia supernova. Chapter 2 details the proper motion measurements made on the forward shock of this remnant, which has led to many key results. I was able to use the results of ii the global shock speed in the remnant to measure the density of neutral hydrogen in the ambient medium into which these shocks expand. In addition, I use the measurements of the shock speed for select portions of the forward shock to search for signatures of efficient cosmic-ray acceleration. Hydrodynamic simulations are then employed to constrain the age and ambient medium density of 0509--67.5, as well as to place limits on the compression factor at the immediate location of the blast wave. Chapter 3 uses the proper motion results from chapter 2 to determine possible asymmetries in the expansion of the remnant for the eastern and western limbs. These measurements are then used as constraints in hydrodynamic simulations to assess the possible dynamical offset of the explosion site compared to the geometric center of 0509?67.5 that we observe today. I find a continuum of possible offsets, which are sensitive to assumptions that are made about the evolutionary history of the remnant, and use the uncertainties in these calculations to determine the area in which to search for a leftover progenitor companion star in the event that the explosion resulted from a single-degenerate system. The stars within this search area are explored with a multi-band photometric study, wherein we determine the mass ranges for these candidates. Chapter four concludes this thesis, recapping the main results from chapters 2 and 3, and highlights the future projects I will carry out that are motivated by my findings in this comprehensive study of the supernova remnant 0509--67.5.

  4. X-ray spectra of supernova remnants

    NASA Technical Reports Server (NTRS)

    Szymkowiak, A. E.

    1985-01-01

    X-ray spectra were obtained from fields in three supernova remnants with the solid state spectrometer of the HEAO 2 satellite. These spectra, which contain lines from K-shell transitions of several abundant elements with atomic numbers between 10 and 22, were compared with various models, including some of spectra that would be produced by adiabatic phase remnants when the time-dependence of the ionization is considered.

  5. Intrauterine Morcellator Devices: The Icon of Hysteroscopic Future or Merely a Marketing Image? A Systematic Review Regarding Safety, Efficacy, Advantages, and Contraindications.

    PubMed

    Noventa, Marco; Ancona, Emanuele; Quaranta, Michela; Vitagliano, Amerigo; Cosmi, Erich; D'Antona, Donato; Gizzo, Salvatore

    2015-10-01

    The aim of this study was to analyze all available evidence regarding the use of intrauterine morcellator (IUM), for treatment of the most prevalent intrauterine benign lesions, compared to both traditional resectoscopy and conventional outpatient operative hysteroscopy in terms of safety, efficacy, contraindications, perioperative complications, operating time, and estimated learning curve. We reported data regarding a total of 1185 patients. Concerning polypectomy and myomectomy procedures, IUM systems demonstrated a better outcome in terms of operative time and fluid deficit compared to standard surgical procedures. Complication rates in the inpatient setting were as follows: 0.02% for IUM using Truclear 8.0 (Smith & Nephew Endoscopy, Andover, Massachusetts) and 0.4% for resectoscopic hysteroscopy. No complications were described using Versapoint devices. Office polipectomy reported a total complication rate of 10.1% using Versapoint device (Ethicon Women's Health and Urology, Somerville, New Jersey) and 1.6% using Truclear 5.0 (Smith & Nephew Endoscopy). The reported recurrence rate after polypectomy was 9.8% using Versapoint device and 2.6% using Truclear 8.0. Finally, the reported intraoperative and postoperative complication rate of IUM related to removal of placental remnants using Truclear 8.0 and MyoSure (Hologic, Marlborough, Massachusetts) was 12.3%. The available evidence allows us to consider IUM devices as a safe, effective, and cost-effective tool for the removal of intrauterine lesions such as polyps, myomas (type 0 and type 1), and placental remnants. Evidence regarding Truclear 5.0 suggests that it may represent the best choice for office hysteroscopy. Further studies are needed to confirm the available evidence and to validate the long-term safety of IUM in procedures for which current data are not exhaustive (placental remnants removal). © The Author(s) 2015.

  6. Suzaku Observations of Thermal and Non-Thermal X-Ray Emission from the Middle-Aged Supernova Remnant G156.2+5.7

    NASA Technical Reports Server (NTRS)

    Katsuda, Satoru; Petre, Robert; Hwang, Una; Yamaguchi, Hiroya; Mori, Koji; Tsunemi, Hiroshi

    2008-01-01

    We present results from X-ray analysis of a Galactic middle-aged supernova remnant (SNR) G156.2+5.7 which is bright and largely extended in X-ray wavelengths, showing a clear circular shape (radius approx.50'). Using the Suzaku satellite, we observed this SNR in three pointings; partially covering the northwestern (NW) rim, the eastern (E) rim, and the central portion of this SNR. In the NW rim and the central portion, we confirm that the X-ray spectra consist of soft and hard-tail emission, while in the E rim we find no significant hard-tail emission. The soft emission is well fitted by either a one-component or two-component non-equilibrium ionization (NEI) model. In the NW and E rims, a one-component (the swept-up interstellar medium) NEI model well represents the soft emission. On the other hand, in the central portion, a two-component (the interstellar medium and the metal-rich ejecta) NEI model fits the soft emission better than the one-component NEI model from a statistical point of view. The relative abundances in the ejecta component suggest that G156.2+5.7 is a remnant from a core-collapse SN explosion whose progenitor mass is less than 15 Solar Mass. The origin of the hard-tail emission detected in the NW rim and the central portion of the SNR is highly likely non-thermal synchrotron emission from relativistic electrons. In the NW rim, the relativistic electrons seems to be accelerated by a forward shock with a slow velocity of APPROX.500 km/sec.

  7. Gamma-Ray Observations of Tycho’s Supernova Remnant with VERITAS and Fermi

    NASA Astrophysics Data System (ADS)

    Archambault, S.; Archer, A.; Benbow, W.; Bird, R.; Bourbeau, E.; Buchovecky, M.; Buckley, J. H.; Bugaev, V.; Cerruti, M.; Connolly, M. P.; Cui, W.; Dwarkadas, V. V.; Errando, M.; Falcone, A.; Feng, Q.; Finley, J. P.; Fleischhack, H.; Fortson, L.; Furniss, A.; Griffin, S.; Hütten, M.; Hanna, D.; Holder, J.; Johnson, C. A.; Kaaret, P.; Kar, P.; Kelley-Hoskins, N.; Kertzman, M.; Kieda, D.; Krause, M.; Kumar, S.; Lang, M. J.; Maier, G.; McArthur, S.; McCann, A.; Moriarty, P.; Mukherjee, R.; Nieto, D.; O'Brien, S.; Ong, R. A.; Otte, A. N.; Park, N.; Pohl, M.; Popkow, A.; Pueschel, E.; Quinn, J.; Ragan, K.; Reynolds, P. T.; Richards, G. T.; Roache, E.; Sadeh, I.; Santander, M.; Sembroski, G. H.; Shahinyan, K.; Slane, P.; Staszak, D.; Telezhinsky, I.; Trepanier, S.; Tyler, J.; Wakely, S. P.; Weinstein, A.; Weisgarber, T.; Wilcox, P.; Wilhelm, A.; Williams, D. A.; Zitzer, B.

    2017-02-01

    High-energy gamma-ray emission from supernova remnants (SNRs) has provided a unique perspective for studies of Galactic cosmic-ray acceleration. Tycho’s SNR is a particularly good target because it is a young, type Ia SNR that has been well-studied over a wide range of energies and located in a relatively clean environment. Since the detection of gamma-ray emission from Tycho’s SNR by VERITAS and Fermi-LAT, there have been several theoretical models proposed to explain its broadband emission and high-energy morphology. We report on an update to the gamma-ray measurements of Tycho’s SNR with 147 hr of VERITAS and 84 months of Fermi-LAT observations, which represent about a factor of two increase in exposure over previously published data. About half of the VERITAS data benefited from a camera upgrade, which has made it possible to extend the TeV measurements toward lower energies. The TeV spectral index measured by VERITAS is consistent with previous results, but the expanded energy range softens a straight power-law fit. At energies higher than 400 GeV, the power-law index is 2.92 ± 0.42stat ± 0.20sys. It is also softer than the spectral index in the GeV energy range, 2.14 ± 0.09stat ± 0.02sys, measured in this study using Fermi-LAT data. The centroid position of the gamma-ray emission is coincident with the center of the remnant, as well as with the centroid measurement of Fermi-LAT above 1 GeV. The results are consistent with an SNR shell origin of the emission, as many models assume. The updated spectrum points to a lower maximum particle energy than has been suggested previously.

  8. Radio Constraints on Long-lived Magnetar Remnants in Short Gamma-Ray Bursts

    NASA Astrophysics Data System (ADS)

    Fong, W.; Metzger, B. D.; Berger, E.; Özel, F.

    2016-11-01

    The merger of a neutron star (NS) binary may result in the formation of a rapidly spinning magnetar. The magnetar can potentially survive for seconds or longer as a supramassive NS before collapsing to a black hole if, indeed, it collapses at all. During this process, a fraction of the magnetar’s rotational energy of ˜1053 erg is transferred via magnetic spin-down to the surrounding ejecta. The resulting interaction between the ejecta and the surrounding circumburst medium powers a year-long or greater synchrotron radio transient. We present a search for radio emission with the Very Large Array following nine short-duration gamma-ray bursts (GRBs) at rest-frame times of ≈1.3-7.6 yr after the bursts, focusing on those events that exhibit early-time excess X-ray emission that may signify the presence of magnetars. We place upper limits of ≲18-32 μJy on the 6.0 GHz radio emission, corresponding to spectral luminosities of ≲(0.05-8.3) × 1039 erg s-1. Comparing these limits to the predicted radio emission from a long-lived remnant and incorporating measurements of the circumburst densities from broadband modeling of short GRB afterglows, we rule out a stable magnetar with an energy of 1053 erg for half of the events in our sample. A supramassive remnant that injects a lower rotational energy of 1052 erg is ruled out for a single event, GRB 050724A. This study represents the deepest and most extensive search for long-term radio emission following short GRBs to date, and thus the most stringent limits placed on the physical properties of magnetars associated with short GRBs from radio observations.

  9. A preliminary report on the geology of the Dennison-Bunn uranium claim, Sandoval County, New Mexico

    USGS Publications Warehouse

    Ridgley, Jennie L.

    1978-01-01

    Uranium at the Dennison-Bunn claim, south of Cuba, N. Mex., along the east margin of the San Juan Basin, occurs in unoxidized gray, fluvial channel sandstone of the Westwater Canyon Member of the Upper Jurassic Morrison Formation. The uranium-bearing sandstone is bounded on the north and south by a variable zone of buff and orange sandstone. Within the mineralized zone, the uranium has been remobilized and reconcentrated along the margins of numerous smaller tongues of oxidized rock in a configuration similar to that found in roll-type uranium deposits. In cross section, these small-scale features are zoned; they have an inner, pale orange, oxidized core, a mineralized redox rim cemented with hematite(?), and an outer-shell of -gray, slightly to moderately mineralized rock. The uranium content in the mineralized rock ranges from 0.001 to 0.07 percent U3O8. The uranium, at this locality, is believed to have originated within the Westwater Canyon Member or to have been derived from the overlying Brushy Basin Member. Based on observed outcrop relations, two hypotheses are proposed for explaining the origin of the occurrence. Briefly these hypotheses are: (1) the mineralized zone represents the remnant of an original roll-type uranium deposit, formed during early Eocene time, which has undergone subsequent oxidation with remobilization and redeposition of uranium around the margins of smaller tongues of oxidized rock; and (2) the mineralized zone represents the remnant of an original tabular deposit which has undergone subsequent oxidation with remobilization and redeposition of uranium around the margins of smaller tongues of oxidized rock.

  10. Physiological responses to dyadic interactions are influenced by neurotypical adults' levels of autistic and empathy traits.

    PubMed

    Truzzi, Anna; Setoh, Peipei; Shinohara, Kazuyuki; Esposito, Gianluca

    2016-10-15

    Autistic traits are distributed on a continuum that ranges from non-clinical to clinical condition. Atypical responses to social situations represent a core feature of the Autism Spectrum Disorders phenotype. Here, we hypothesize that atypical physiological responses to social stimuli may predict non-clinical autistic and empathy traits levels. We measured physiological responses (heart rate, facial temperature) of 40 adults (20F) while showing them 24 movies representing dyadic interactions. Autistic traits were assessed through Autism Quotient questionnaire (AQ), while empathy traits were measured using the Empathy Quotient questionnaire (EQ). Opposite correlations between AQ and EQ scores and physiological responses were found. Analysis of physiological responses revealed that individuals with better social abilities, low AQ and high EQ, show opposite activation patterns compared to people with high AQ and low EQ. Findings show that physiological responses could be biomarkers for people's autistic traits and social abilities. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Gravitational-Wave Luminosity of Binary Neutron Stars Mergers

    NASA Astrophysics Data System (ADS)

    Zappa, Francesco; Bernuzzi, Sebastiano; Radice, David; Perego, Albino; Dietrich, Tim

    2018-03-01

    We study the gravitational-wave peak luminosity and radiated energy of quasicircular neutron star mergers using a large sample of numerical relativity simulations with different binary parameters and input physics. The peak luminosity for all the binaries can be described in terms of the mass ratio and of the leading-order post-Newtonian tidal parameter solely. The mergers resulting in a prompt collapse to black hole have the largest peak luminosities. However, the largest amount of energy per unit mass is radiated by mergers that produce a hypermassive neutron star or a massive neutron star remnant. We quantify the gravitational-wave luminosity of binary neutron star merger events, and set upper limits on the radiated energy and the remnant angular momentum from these events. We find that there is an empirical universal relation connecting the total gravitational radiation and the angular momentum of the remnant. Our results constrain the final spin of the remnant black hole and also indicate that stable neutron star remnant forms with super-Keplerian angular momentum.

  12. Gravitational-Wave Luminosity of Binary Neutron Stars Mergers.

    PubMed

    Zappa, Francesco; Bernuzzi, Sebastiano; Radice, David; Perego, Albino; Dietrich, Tim

    2018-03-16

    We study the gravitational-wave peak luminosity and radiated energy of quasicircular neutron star mergers using a large sample of numerical relativity simulations with different binary parameters and input physics. The peak luminosity for all the binaries can be described in terms of the mass ratio and of the leading-order post-Newtonian tidal parameter solely. The mergers resulting in a prompt collapse to black hole have the largest peak luminosities. However, the largest amount of energy per unit mass is radiated by mergers that produce a hypermassive neutron star or a massive neutron star remnant. We quantify the gravitational-wave luminosity of binary neutron star merger events, and set upper limits on the radiated energy and the remnant angular momentum from these events. We find that there is an empirical universal relation connecting the total gravitational radiation and the angular momentum of the remnant. Our results constrain the final spin of the remnant black hole and also indicate that stable neutron star remnant forms with super-Keplerian angular momentum.

  13. Hot interstellar tunnels. 1: Simulation of interacting supernova remnants

    NASA Technical Reports Server (NTRS)

    Smith, B. W.

    1976-01-01

    The theory required to build a numerical simulation of interacting supernova remnants is developed. The hot cavities within a population of remnants will become connected, with varying ease and speed, for a variety of assumed conditions in the outer shells of old remnants. Apparently neither radiative cooling nor thermal conduction in a large-scale galactic magnetic field can destroy hot cavity regions, if they grow, faster than they are reheated by supernova shock waves, but interstellar mass motions disrupt the contiguity of extensive cavities necessary for the dispersal of these shocks over a wide volume. Monte Carlo simulations show that a quasi-equilibrium is reached in the test space within 10 million yrs of the first supernova and is characterized by an average cavity filling fraction of the interstellar volume. Aspects of this equilibrium are discussed for a range of supernova rates. Two predictions are not confirmed within this range: critical growth of hot regions to encompass the entire medium, and the efficient quenching of a remnant's expansion by interaction with other cavities.

  14. Remnant Geometric Hall Response in a Quantum Quench.

    PubMed

    Wilson, Justin H; Song, Justin C W; Refael, Gil

    2016-12-02

    Out-of-equilibrium systems can host phenomena that transcend the usual restrictions of equilibrium systems. Here, we unveil how out-of-equilibrium states, prepared via a quantum quench in a two-band system, can exhibit a nonzero Hall-type current-a remnant Hall response-even when the instantaneous Hamiltonian is time reversal symmetric (in contrast to equilibrium Hall currents). Interestingly, the remnant Hall response arises from the coherent dynamics of the wave function that retain a remnant of its quantum geometry postquench, and can be traced to processes beyond linear response. Quenches in two-band Dirac systems are natural venues for realizing remnant Hall currents, which exist when either mirror or time-reversal symmetry are broken (before or after the quench). Its long time persistence, sensitivity to symmetry breaking, and decoherence-type relaxation processes allow it to be used as a sensitive diagnostic of the complex out-of-equilibrium dynamics readily controlled and probed in cold-atomic optical lattice experiments.

  15. Evolution of Supernova Remnants

    NASA Astrophysics Data System (ADS)

    Arbutina, B.

    2017-12-01

    This book, both a monograph and a graduate textbook, is based on my original research and partly on the materials prepared earlier for the 2007 and 2008 IARS Astrophysics Summer School in Istanbul, AstroMundus course 'Supernovae and Their Remnants' that was held for the first time in 2011 at the Department of Astronomy, Faculty of Mathematics, University of Belgrade, and a graduate course 'Evolution of Supernova Remnants' that I teach at the aforementioned university. The first part Supernovae (introduction, thermonuclear supernovae, core-collapse supernovae) provides introductory information and explains the classification and physics of supernova explosions, while the second part Supernova remnants (introduction, shock waves, cosmic rays and particle acceleration, magnetic fields, synchrotron radiation, hydrodynamic and radio evolution of supernova remnants), which is the field I work in, is more detailed in scope i.e. technical/mathematical. Special attention is paid to details of mathematical derivations that often cannot be found in original works or available literature. Therefore, I believe it can be useful to both, graduate students and researchers interested in the field.

  16. Summary of Quaternary geology of the Municipality of Anchorage, Alaska

    USGS Publications Warehouse

    Schmoll, H.R.; Yehle, L.A.; Updike, R.G.

    1999-01-01

    Quaternary geology of the Upper Cook Inlet region is dominated by deposits of glacier retreats that followed repeated advances from both adjacent and more distant mountains. At several levels high on the mountains, there are remnant glacial deposits and other features of middle or older Pleistocene age. Late Pleistocene lateral moraines along the Chugach Mountain front represent successively younger positions of ice retreat from the last glacial maximum. As the trunk glacier retreated northeastward up the Anchorage lowland, Cook Inlet transgressed the area, depositing the Bootlegger Cove Formation and Tudor Road deposits. The glacier then readvanced to form the latest Pleistocene Elmendorf Moraine, a prominent feature that trends across the Anchorage lowland. Extensive alluvium was deposited both concurrently and somewhat later as Cook Inlet regressed. Mountain valleys contain (1) locally preserved moraines possibly of early Holocene age; (2) poorly preserved moraine remnants of older late Holocene age; and (3) well-preserved moraines formed mainly during the Little Ice Age. Glaciers still occupy large parts of the mountains, the upper ends of some mountain valleys, and small cirques. Holocene landslide deposits, including those formed during the great Alaska earthquake of 1964, occur throughout the area, especially along bluffs containing the Bootlegger Cove Formation.

  17. A continuous record of tectonic evolution from 3.5 Ga to 2.6 Ga in Swaziland and northern Natal

    NASA Technical Reports Server (NTRS)

    Hunter, D. R.; Wilson, A. H.; Versfeld, J. A.; Allen, A. R.; Smith, R. G.; Sleigh, D. W. W.; Groenewald, P. B.; Chutter, G. M.; Preston, V. A.

    1986-01-01

    The approx. 3.5 Ga-old bimodal suite underlying an extensive area in southwestern Swaziland comprises the oldest-dated sialic rocks in the Kaapvaal structural province. The suite consists of leucocratic, layered tonalitic-trondhjemitic gneisses and amphibolites characterized by the effects of repeated high strains. This suite is considered to represent a sialic basement on which metavolcanic and metasedimentary rocks, now preserved as scattered greenstone remnants, accumulated. Direct evidence to confirm this temporal relationship is lacking, but structural data from the Dwalile, Assegaai and Commondale areas indicate that (1) the bimodal gneisses experienced a complex structural history prior to the first recognizable deformation in the supracrustal rocks (i.e., D1 in the supracrustals is equivalent to Dn + 1 in the gneisses) and (2) scattered remnants of the Dwalile rocks infolded with the bimodal suite structurally overlie the gneisses and are preserved in synformal keels. Significant proportions of metaquartzites and metapelites are present in the Assegaai greenstone sequence, the presence of which implies the existence of felsic crust in the source area from which these sediments were derived, a conclusion that is consistent with the structural data.

  18. A Model of the Vela Supernova Remnant

    NASA Astrophysics Data System (ADS)

    Gvaramadze, Vasilii

    2000-10-01

    A model of the Vela supernova remnant (SNR) based on a cavity explosion of a supernova (SN) star is proposed. It is suggested that the general structure of the remnant is determined by the interaction of the SN blast wave with a massive shell created by the SN progenitor (15-20 M_solar) star. A possible origin of the nebula of hard X-ray emission detected around the Vela pulsar is discussed.

  19. Postprandial lipoprotein metabolism; VLDL vs chylomicrons

    PubMed Central

    Nakajima, Katsuyuki; Nakano, Takamitsu; Tokita, Yoshiharu; Nagamine, Takeaki; Inazu, Akihiro; Kobayashi, Junji; Mabuchi, Hiroshi; Stanhope, Kimber L.; Havel, Peter J.; Okazaki, Mitsuyo; Ai, Masumi; Tanaka, Akira

    2012-01-01

    Since Zilversmit first proposed postprandial lipemia as the most common risk of cardiovascular disease, chylomicrons (CM) and CM remnants have been thought to be the major lipoproteins which are increased in the postprandial hyperlipidemia. However, it has been shown over the last two decades that the major increase in the postprandial lipoproteins after food intake occurs in the very low density lipoprotein (VLDL) remnants (apoB100 particles), not CM or CM remnants (apoB48 particles). This finding was obtained using the following three analytical methods; isolation of remnant-like lipoprotein particles (RLP) with specific antibodies, separation and detection of lipoprotein subclasses by gel permeation HPLC and determination of apoB48 in fractionated lipoproteins by a specific ELISA. The amount of the apoB48 particles in the postprandial RLP is significantly less than the apoB100 particles, and the particle sizes of apoB48 and apoB100 in RLP are very similar when analyzed by HPLC. Moreover, CM or CM remnants having a large amount of TG were not found in the postprandial RLP. Therefore, the major portion of the TG which is increased in the postprandial state is composed of VLDL remnants, which have been recognized as a significant risk for cardiovascular disease. PMID:21531214

  20. Matrix Intensification Alters Avian Functional Group Composition in Adjacent Rainforest Fragments

    PubMed Central

    Deikumah, Justus P.; McAlpine, Clive A.; Maron, Martine

    2013-01-01

    Conversion of farmland land-use matrices to surface mining is an increasing threat to the habitat quality of forest remnants and their constituent biota, with consequences for ecosystem functionality. We evaluated the effects of matrix type on bird community composition and the abundance and evenness within avian functional groups in south-west Ghana. We hypothesized that surface mining near remnants may result in a shift in functional composition of avifaunal communities, potentially disrupting ecological processes within tropical forest ecosystems. Matrix intensification and proximity to the remnant edge strongly influenced the abundance of members of several functional guilds. Obligate frugivores, strict terrestrial insectivores, lower and upper strata birds, and insect gleaners were most negatively affected by adjacent mining matrices, suggesting certain ecosystem processes such as seed dispersal may be disrupted by landscape change in this region. Evenness of these functional guilds was also lower in remnants adjacent to surface mining, regardless of the distance from remnant edge, with the exception of strict terrestrial insectivores. These shifts suggest matrix intensification can influence avian functional group composition and related ecosystem-level processes in adjacent forest remnants. The management of matrix habitat quality near and within mine concessions is important for improving efforts to preserveavian biodiversity in landscapes undergoing intensification such as through increased surface mining. PMID:24058634

  1. Matrix intensification alters avian functional group composition in adjacent rainforest fragments.

    PubMed

    Deikumah, Justus P; McAlpine, Clive A; Maron, Martine

    2013-01-01

    Conversion of farmland land-use matrices to surface mining is an increasing threat to the habitat quality of forest remnants and their constituent biota, with consequences for ecosystem functionality. We evaluated the effects of matrix type on bird community composition and the abundance and evenness within avian functional groups in south-west Ghana. We hypothesized that surface mining near remnants may result in a shift in functional composition of avifaunal communities, potentially disrupting ecological processes within tropical forest ecosystems. Matrix intensification and proximity to the remnant edge strongly influenced the abundance of members of several functional guilds. Obligate frugivores, strict terrestrial insectivores, lower and upper strata birds, and insect gleaners were most negatively affected by adjacent mining matrices, suggesting certain ecosystem processes such as seed dispersal may be disrupted by landscape change in this region. Evenness of these functional guilds was also lower in remnants adjacent to surface mining, regardless of the distance from remnant edge, with the exception of strict terrestrial insectivores. These shifts suggest matrix intensification can influence avian functional group composition and related ecosystem-level processes in adjacent forest remnants. The management of matrix habitat quality near and within mine concessions is important for improving efforts to preserveavian biodiversity in landscapes undergoing intensification such as through increased surface mining.

  2. The Impact of Progenitor Mass Loss on the Dynamical and Spectral Evolution of Supernova Remnants

    NASA Astrophysics Data System (ADS)

    Patnaude, Daniel J.; Lee, Shiu-Hang; Slane, Patrick O.; Badenes, Carles; Nagataki, Shigehiro; Ellison, Donald C.; Milisavljevic, Dan

    2017-11-01

    There is now substantial evidence that the progenitors of some core-collapse supernovae undergo enhanced or extreme mass loss prior to explosion. The imprint of this mass loss is observed in the spectra and dynamics of the expanding blast wave on timescales of days to years after core collapse, and the effects on the spectral and dynamical evolution may linger long after the supernova has evolved into the remnant stage. In this paper, we present, for the first time, largely self-consistent end-to-end simulations for the evolution of a massive star from the pre-main sequence, up to and through core collapse, and into the remnant phase. We present three models and compare and contrast how the progenitor mass-loss history impacts the dynamics and spectral evolution of the supernovae and supernova remnants. We study a model that only includes steady mass loss, a model with enhanced mass loss over a period of ˜5000 yr prior to core collapse, and a model with extreme mass loss over a period of ˜500 yr prior to core collapse. The models are not meant to address any particular supernova or supernova remnant, but rather to highlight the important role that the progenitor evolution plays in the observable qualities of supernovae and supernova remnants. Through comparisons of these three different progenitor evolution scenarios, we find that the mass loss in late stages (during and after core carbon burning) can have a profound impact on the dynamics and spectral evolution of the supernova remnant centuries after core collapse.

  3. GW170817 Most Likely Made a Black Hole

    NASA Astrophysics Data System (ADS)

    Pooley, David; Kumar, Pawan; Wheeler, J. Craig; Grossan, Bruce

    2018-06-01

    There are two outstanding issues regarding the neutron-star merger event GW170817: the nature of the compact remnant and the interstellar shock. The mass of the remnant of GW170817, ∼2.7 {M}ȯ , implies that the remnant could be either a massive rotating neutron star, or a black hole. We report Chandra Director’s Discretionary Time observations made in 2017 December and 2018 January, and we reanalyze earlier observations from 2017 August and 2017 September, in order to address these unresolved issues. We estimate the X-ray flux from a neutron star remnant and compare that to the measured X-ray flux. If we assume that the spin-down luminosity of any putative neutron star is converted to pulsar wind nebula X-ray emission in the 0.5–8 keV band with an efficiency of 10‑3, for a dipole magnetic field with 3 × 1011 G < B < 1014 G, a rising X-ray signal would result and would be brighter than that observed by day 107; we therefore conclude that the remnant of GW170817 is most likely a black hole. Independent of any assumptions of X-ray efficiency, however, if the remnant is a rapidly rotating magnetized neutron star, the total energy in the external shock should rise by a factor ∼102 (to ∼1052 erg) after a few years; therefore, Chandra observations over the next year or two that do not show substantial brightening will rule out such a remnant. The same observations can distinguish between two different models for the relativistic outflow, either an angular or radially varying structure.

  4. The influence of massive black hole binaries on the morphology of merger remnants

    NASA Astrophysics Data System (ADS)

    Bortolas, E.; Gualandris, A.; Dotti, M.; Read, J. I.

    2018-06-01

    Massive black hole (MBH) binaries, formed as a result of galaxy mergers, are expected to harden by dynamical friction and three-body stellar scatterings, until emission of gravitational waves (GWs) leads to their final coalescence. According to recent simulations, MBH binaries can efficiently harden via stellar encounters only when the host geometry is triaxial, even if only modestly, as angular momentum diffusion allows an efficient repopulation of the binary loss cone. In this paper, we carry out a suite of N-body simulations of equal-mass galaxy collisions, varying the initial orbits and density profiles for the merging galaxies and running simulations both with and without central MBHs. We find that the presence of an MBH binary in the remnant makes the system nearly oblate, aligned with the galaxy merger plane, within a radius enclosing 100 MBH masses. We never find binary hosts to be prolate on any scale. The decaying MBHs slightly enhance the tangential anisotropy in the centre of the remnant due to angular momentum injection and the slingshot ejection of stars on nearly radial orbits. This latter effect results in about 1 per cent of the remnant stars being expelled from the galactic nucleus. Finally, we do not find any strong connection between the remnant morphology and the binary hardening rate, which depends only on the inner density slope of the remnant galaxy. Our results suggest that MBH binaries are able to coalesce within a few Gyr, even if the binary is found to partially erase the merger-induced triaxiality from the remnant.

  5. The fate of the Antennae galaxies

    NASA Astrophysics Data System (ADS)

    Lahén, Natalia; Johansson, Peter H.; Rantala, Antti; Naab, Thorsten; Frigo, Matteo

    2018-04-01

    We present a high-resolution smoothed particle hydrodynamic simulation of the Antennae galaxies (NGC 4038/4039) and follow the evolution 3 Gyr beyond the final coalescence. The simulation includes metallicity-dependent cooling, star formation, and both stellar feedback and chemical enrichment. The simulated best-match Antennae reproduce well both the observed morphology and the off-nuclear starburst. We also produce for the first time a simulated two-dimensional (2D) metallicity map of the Antennae and find good agreement with the observed metallicity of off-nuclear stellar clusters; however, the nuclear metallicities are overproduced by ˜0.5 dex. Using the radiative transfer code SKIRT, we produce multiwavelength observations of both the Antennae and the merger remnant. The 1-Gyr-old remnant is well fitted with a Sérsic profile of n = 7.07, and with an r-band effective radius of re = 1.6 kpc and velocity dispersion of σe = 180 km s-1 the remnant is located on the Fundamental Plane of early-type galaxies (ETGs). The initially blue Antennae remnant evolves on to the red sequence after ˜2.5 Gyr of secular evolution. The remnant would be classified as a fast rotator, as the specific angular momentum evolves from λRe ≈ 0.11 to 0.14 during its evolution. The remnant shows ordered rotation and a double peaked maximum in the mean 2D line-of-sight velocity. These kinematical features are relatively common amongst local ETGs and we specifically identify three local ETGs (NGC 3226, NGC 3379, and NGC 4494) in the atlas3D sample, whose photometric and kinematic properties most resemble the Antennae remnant.

  6. Kinetic analysis of contralateral liver hypertrophy after radioembolization of primary and metastatic liver tumors.

    PubMed

    Orcutt, Sonia T; Abuodeh, Yazan; Naghavi, Arash; Frakes, Jessica; Hoffe, Sarah; Kis, Bela; Anaya, Daniel A

    2018-05-01

    Radioembolization induces liver hypertrophy, although the extent and rate of hypertrophy are unknown. Our goal was to examine the kinetics of contralateral liver hypertrophy after transarterial radioembolization. A retrospective study (2010-2014) of treatment-naïve patients with primary/secondary liver malignancies undergoing right lobe radioembolization was performed. Computed tomography volumetry was performed before and 1, 3, and 6 months after radioembolization. Outcomes of interest were left lobe (standardized future liver remnant) degree of hypertrophy, kinetic growth rate, and ability to reach goal standardized future liver remnant ≥40%. Medians were compared with the Kruskall-Wallis test. Time to event analysis was used to estimate time to reach goal standardized future liver remnant. In the study, 25 patients were included. At 1, 3, and 6 months, median degree of hypertrophy was 4%, 8%, and 12% (P < .001), degree of hypertrophy relative to baseline future liver remnants was 11%, 17%, and 31% (P = .015), and kinetic growth rate was 0.8%, 0.5%, and 0.4%/week (P = .002). In patients with baseline standardized future liver remnant <40% (N= 16), median time to reach standardized future liver remnant ≥40% was 7.3 months, with 75% accomplishing standardized future liver remnant ≥40% at 8.2 months. Radioembolization induces hypertrophy of the contralateral lobe to a similar extent as existing methods, although at a lower rate. The role of radioembolization as a dual therapy (neoadjuvant and hypetrophy-inducing) for selected patients needs to be studied. (Surgery 2017;160:XXX-XXX.). Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Presence of Tablet Remnants of Nevirapine Extended-Release in Stools and Its Impact on Virological Outcome in HIV-1-Infected Patients: A Prospective Cohort Study

    PubMed Central

    Lee, Yi-Chieh; Lin, Shu-Wen; Chen, Mao-Yuan; Chang, Sui-Yuan; Kuo, Ching-Hua; Sheng, Wang-Huei; Hsieh, Szu-Min; Sun, Hsin-Yun; Chang, Hsi-Yen; Wu, Mon-Ro; Liu, Wen-Chun; Wu, Pei-Ying; Yang, Shang-Ping; Zhang, Jun-Yu; Su, Yi-Ching; Luo, Yi-Zhen; Hung, Chien-Ching; Chang, Shan-Chwen

    2015-01-01

    Background Nevirapine extended-release (NVP-XR) taken once daily remains an effective antiretroviral agent for patients infected with HIV-1 strains that do not harbor resistance mutations. Presence of tablet remnants of NVP XR in stools was reported in 1.19% and 3.05% of subjects in two clinical trials. However, the prevalence may have been underestimated because the information was retrospectively collected in the studies. Methods Between April and December 2014, we prospectively inquired about the frequency of noticing tablet remnants of NVP XR in stools in HIV-1-infected patients who switched to antiretroviral regimens containing NVP XR plus 2 nucleos(t)ide reverse-transcriptase inhibitors. Patients were invited to participate in therapeutic drug monitoring of plasma concentrations of NVP 12 or 24 hours after taking the previous dose (C12 and C24, respectively) of NVP XR using high-performance liquid chromatography. The information on clinical characteristics, including plasma HIV RNA load and CD4 lymphocyte count, at baseline and during follow-up was recorded. Results During the 9-month study period, 272 patients switched to NVP XR-based regimens and 60 (22.1%) noticed tablet remnants of NVP XR in stools, in whom 54.2% reported noticing the tablet remnants at least once weekly. Compared with patients who did not notice tablet remnants, those who noticed tablet remnants had a higher mean CD4 lymphocyte count (629 vs 495 cells/mm3, P = 0.0002) and a similar mean plasma HIV RNA load (1.57 vs 1.61 log10 copies/mL, P = 0.76) on switch. At about 12 and 24 weeks after switch, patients who noticed tablet remnants continued to have a similar mean plasma HIV RNA load (1.39 vs 1.43 log10 copies/mL, P = 0.43; and 1.30 vs 1.37 log10 copies/mL, P = 0.26, respectively), but had a lower median NVP C12 (3640 vs 4730 ng/mL, P = 0.06), and a similar median NVP C24 (3220 vs 3330 ng/ml, P = 0.95) when compared with those who did not notice tablet remnants. Conclusions The presence of tablet remnants of NVP XR in stools is not uncommon in HIV-1-infected Taiwanese patients receiving NVP XR-based antiretroviral regimens, which does not have an adverse impact on the virological and immunological outcomes. PMID:26465325

  8. Thermal tolerance of the invasive Belonesox belizanus, pike killifish, throughout ontogeny.

    PubMed

    Kerfoot, James Roy

    2012-06-01

    The goal of this study was to characterize the variability of thermal tolerances between life-history stages of the invasive Belonesox belizanus and attempt to describe the most likely stage of dispersal across south Florida. In the laboratory, individuals were acclimated to three temperatures (20, 25, or 30°C). Upper and lower lethal thermal limits and temperatures at which feeding ceased were measured for neonates, juveniles, and adults. Thermal tolerance polygons were developed to represent the thermal tolerance range of each life-history stage. Results indicated that across acclimation temperatures upper lethal thermal limits were similar for all three stages (38°C). However, minimum lethal thermal limits were significantly different at the 30°C acclimation temperature, where juveniles (9°C) had an approximately 2.0°C and 4.0°C lower minimum lethal thermal limit compared with adults and neonates, respectively. According to thermal tolerance polygons, juveniles had an average tolerance polygonal area almost 20°C(2) larger than adults, indicating the greatest thermal tolerance of the three life-history stages. Variation in cessation of feeding temperatures indicated no significant difference between juveniles and adults. Overall, results of this study imply that juvenile B. belizanus may be equipped with the physiological flexibility to exercise habitat choice and reduce potential intraspecific competition with adults for limited food resources. Given its continued dispersal, the minimum thermal limit of juveniles may aid in continued dispersal of this species, especially during average winter temperatures throughout Florida where juveniles could act to preserve remnant populations until seasonal temperatures increase. © 2012 WILEY PERIODICALS, INC.

  9. Recent Progress on Supernova Remnants - Progenitors, Evolution, Cosmic-ray Acceleration

    NASA Astrophysics Data System (ADS)

    Bamba, A.

    2017-10-01

    Supernova remnants supplies heavy elements, kinetic and thermal energies, and cosmic rays, into the universe, and are the key sources to make the diversity of the universe. On the other hand, we do not know the fundamental issues of supernova remnants, such as (1) what their main progenitors are, (2) how they evolve into the realistic (non-uniform) interstellar space, and (3) which type of supernova remnants can accelerate cosmic rays to the knee energy. Recent X-ray studies with XMM-Newton, Chandra, Suzaku, NuSTAR, and Hitomi, progressed understandings of these issues, and found that each issue connect others tightly. In this paper, we will overview these progresses with focusing the above three topics, and discuss what we should do next.

  10. G25.5 + 0.2 - A very young galactic supernova remnant

    NASA Technical Reports Server (NTRS)

    Cowan, John J.; Ekers, R. D.; Goss, W. M.; Sramek, R. A.; Roberts, Douglas A.

    1989-01-01

    Radio emission has been detected from a compact source which satisfies the criteria for a very young galactic supernova remnant. The source, G25.5 + 0.2 has a partially-filled shell structure, a total integrated flux density at 20 cm of 315 mJy, and a flat spectrum between 2 and 20 cm. Observations at 843 and 327 MHz indicate thermal absorption at low frequencies with a turnover in the spectrum near 1 GHz. It is suggested that the lower limit for the age of the supernova remnant is 25 yr, while the upper limit is about 100 yr. It is concluded that G25.5 + 0.2 could be the youngest known supernova remnant in the Galaxy.

  11. Three cases of laparoscopic total gastrectomy with intracorporeal esophagojejunostomy for gastric cancer in remnant stomach.

    PubMed

    Pan, Yu; Mou, Yi-Ping; Chen, Ke; Xu, Xiao-Wu; Cai, Jia-Qin; Wu, Di; Zhou, Yu-Cheng

    2014-11-13

    Gastric cancer in remnant stomach is a rare tumor but with poor prognosis. Compared with conventional open surgery, laparoscopic gastrectomy has potential benefits for these patients due to advantages resulting from its minimally invasive approach. Herein, we report on three patients with gastric cancer in remnant stomach who underwent laparoscopic total gastrectomy with intracorporeal esophagojejunostomy successfully. The operative time was 280, 250 and 225 minutes, the estimated blood loss was 100, 80 and 50 ml and the length of postoperative hospital stay was seven, eight and nine days respectively. Our experience has suggested that laparoscopic total gastrectomy with intracorporeal esophagojejunostomy can be a safe, feasible and promising option for patients with gastric cancer in remnant stomach.

  12. Two evolved supernova remnants with newly identified Fe-rich cores in the Large Magellanic Cloud

    NASA Astrophysics Data System (ADS)

    Kavanagh, P. J.; Sasaki, M.; Bozzetto, L. M.; Points, S. D.; Crawford, E. J.; Dickel, J.; Filipović, M. D.; Haberl, F.; Maggi, P.; Whelan, E. T.

    2016-02-01

    Aims: We present a multi-wavelength analysis of the evolved supernova remnants MCSNR J0506-7025 and MCSNR J0527-7104 in the Large Magellanic Cloud. Methods: We used observational data from XMM-Newton, the Australian Telescope Compact Array, and the Magellanic Cloud Emission Line Survey to study their broad-band emission and used Spitzer and H I data to gain a picture of the environment into which the remnants are expanding. We performed a multi-wavelength morphological study and detailed radio and X-ray spectral analyses to determine their physical characteristics. Results: Both remnants were found to have bright X-ray cores, dominated by Fe L-shell emission, which is consistent with reverse shock-heated ejecta with determined Fe masses in agreement with Type Ia explosion yields. A soft X-ray shell, which is consistent with swept-up interstellar medium, was observed in MCSNR J0506-7025, suggestive of a remnant in the Sedov phase. Using the spectral fit results and the Sedov self-similar solution, we estimated the age of MCSNR J0506-7025 to be ~16-28 kyr, with an initial explosion energy of (0.07-0.84) × 1051 erg. A soft shell was absent in MCSNR J0527-7104, with only ejecta emission visible in an extremely elongated morphology that extends beyond the optical shell. We suggest that the blast wave has broken out into a low density cavity, allowing the shock heated ejecta to escape. We find that the radio spectral index of MCSNR J0506-7025 is consistent with the standard -0.5 for supernova remnants. Radio polarisation at 6 cm indicates a higher degree of polarisation along the western front and at the eastern knot with a mean fractional polarisation across the remnant of P ≅ (20 ± 6)%. Conclusions: The detection of Fe-rich ejecta in the remnants suggests that both resulted from Type Ia explosions. The newly identified Fe-rich cores in MCSNR J0506-7025 and MCSNR J0527-7104 make them members of the expanding class of evolved Fe-rich remnants in the Magellanic Clouds. Based on observations obtained with XMM-Newton, an ESA science mission with instruments and contributions directly funded by ESA Member States and NASA.

  13. INTERACTION BETWEEN THE SUPERNOVA REMNANT HB 3 AND THE NEARBY STAR-FORMING REGION W3

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhou, Xin; Yang, Ji; Fang, Min

    We performed millimeter observations of CO lines toward the supernova remnant (SNR) HB 3. Substantial molecular gas around −45 km s{sup −1} is detected in the conjunction region between the SNR HB 3 and the nearby W3 complex. This molecular gas is distributed along the radio continuum shell of the remnant. Furthermore, the shocked molecular gas indicated by line wing broadening features is also distributed along the radio shell and inside it. By both morphological correspondence and dynamical evidence, we confirm that the SNR HB 3 interacts with the −45 km s{sup −1} molecular cloud (MC), in essence, with the nearby H ii region/MC complexmore » W3. The redshifted line wing broadening features indicate that the remnant is located at the nearside of the MC. With this association, we could place the remnant at the same distance as the W3/W4 complex, which is 1.95 ± 0.04 kpc. The spatial distribution of aggregated young stellar object candidates shows a correlation with the shocked molecular strip associated with the remnant. We also find a binary clump of CO at ( l = 132.°94, b = 1.°12) around −51.5 km s{sup −1} inside the projected extent of the remnant, and it is associated with significant mid-infrared emission. The binary system also has a tail structure resembling the tidal tails of interacting galaxies. According to the analysis of CO emission lines, the larger clump in this binary system is about stable, and the smaller clump is significantly disturbed.« less

  14. XMM-Newton observation of the supernova remnant Kes 78 (G32.8-0.1): Evidence of shock-cloud interaction

    NASA Astrophysics Data System (ADS)

    Miceli, M.; Bamba, A.; Orlando, S.; Zhou, P.; Safi-Harb, S.; Chen, Y.; Bocchino, F.

    2017-03-01

    Context. The Galactic supernova remnant Kes 78 is surrounded by dense molecular clouds, whose projected position overlaps with the extended HESS γ-ray source HESS J1852-000. The X-ray emission from the remnant has recently been revealed by Suzaku observations, which have shown indications for a hard X-ray component in the spectra that might be associated with synchrotron radiation. Aims: We describe the spatial distribution of the physical properties of the X-ray emitting plasma and reveal the effects of the interaction of the remnant with the inhomogeneous ambient medium. We also investigate the origin of the γ-ray emission, which may be inverse-Compton radiation associated with X-ray synchrotron-emitting electrons or hadronic emission originating from the impact of high-energy protons on the nearby clouds. Methods: We analyzed an XMM-Newton EPIC observation of Kes 78 by performing image analysis and spatially resolved spectral analysis on a set of three regions. We tested our findings against the observations of the 12CO and 13CO emission in the environment of the remnant. Results: We reveal the complex X-ray morphology of Kes 78 and find variations in the spectral properties of the plasma, with significantly denser and cooler material at the eastern edge of the remnant, which we interpret as a signature of interaction with a molecular cloud. We also exclude that narrow filaments emit the X-ray synchrotron radiation. Conclusions: Assuming that the very high energy γ-ray emission is associated with Kes 78, the lack of synchrotron emission rules out a leptonic origin. A hadronic origin is further supported by evidence of interaction of the remnant with a dense molecular cloud in its eastern limb.

  15. Liver Function Assessment Using Technetium 99m-Galactosyl Single-Photon Emission Computed Tomography/CT Fusion Imaging: A Prospective Trial.

    PubMed

    Okabayashi, Takehiro; Shima, Yasuo; Morita, Sojiro; Shimada, Yasuhiro; Sumiyoshi, Tatsuaki; Sui, Kenta; Iwata, Jun; Iiyama, Tatsuo

    2017-12-01

    The prediction of postoperative liver function remains a largely subjective practice based on CT volumetric analysis. However, future liver volume after a hepatectomy is not the only factor that contributes to postoperative liver function and outcomes. In this prospective trial, 185 consecutive patients who underwent liver operations between 2014 and 2015 were studied. Volumetric and functional rates of remnant liver were measured using technetium 99m-galactosyl human serum albumin single-photon emission computed tomography/CT fusion imaging to evaluate post-hepatectomy remnant liver function. Remnant indocyanine green clearance rate using galactosyl (KGSA) (KGSA × functional rate) was used to predict future remnant liver function. Hepatectomy was considered safe for patients with remnant KGSA values ≥0.05, and the primary end point was to determine the accuracy and reliability of this criteria. The prediction of the 90-day major complication and mortality rates was assessed. Median hospital stay was 9 days and median ICU stay was 1 day, with only 1 in-hospital death (90-day mortality rate 0.5%). Overall morbidity rate evaluated according to the Clavien-Dindo classification was 9%. For post-hepatectomy liver failure definitions, the International Study Group of Liver Surgery definition was fulfilled in 14 patients (8%), with the majority being grade B (50%), compared with 2 patients (1%) fulfilling the "50-50" criteria, and 0 patients (0%) fulfilling the Peak Bili >7 criteria. Results of this study showed that remnant KGSA provided information that allowed us to predict remnant liver function. This information will be important for surgeons when deciding on a treatment plan for patients with liver diseases. (ClinicalTrials.gov ID: NCT02013895). Copyright © 2017 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

  16. Viable Cancer Cells in the Remnant Stomach are a Potential Source of Peritoneal Metastasis after Curative Distal Gastrectomy for Gastric Cancer.

    PubMed

    Murata, Satoshi; Yamamoto, Hiroshi; Yamaguchi, Tsuyoshi; Kaida, Sachiko; Ishida, Mitsuaki; Kodama, Hirokazu; Takebayashi, Katsushi; Shimizu, Tomoharu; Miyake, Toru; Tani, Tohru; Kushima, Ryoji; Tani, Masaji

    2016-09-01

    The mechanisms underlying peritoneal metastasis (PM) after curative gastrectomy for gastric cancer (GC) are not well elucidated. This study assessed whether viable cancer cells, including cancer stemlike cells (CSCs), were present in the remnant stomach immediately before gastrointestinal (GI) tract reconstruction because these could be a source of PM after gastrectomy. Saline fluid used for remnant stomach lumen irrigation before GI reconstruction was prospectively collected from 142 consecutive patients undergoing distal gastrectomy for GC and cytologically examined. Proliferative activity (Ki67 staining) and stemness (expression of the CSC surface markers CD44s or CD44v6) were evaluated in detected cancer cells. Viable cancer cells were detected in 33 (23.2 %) of the 142 remnant stomachs. These cells formed clusters and stained positively for Ki67, indicating proliferation. Cancer cells in remnant stomachs and surface cancer cells in primary GCs from 10 (30.3 %) of these 33 cases also stained positively for CD44s or CD44v6. In a multiple logistic regression analysis, advanced cancer (odds ratio [OR], 4.65; 95 % confidence interval [CI], 1.32-16.4; P = 0.017), tumor size of 40 mm or larger (OR, 3.78; 95 % CI, 1.12-12.8; P = 0.033), and histologic differentiation (OR, 3.10; 95 % CI, 1.30-7.40; P = 0.011) were associated independently with the presence of cancer cells in the remnant stomach. Viable, proliferative, and clustered cancer cells, including CSCs, were found in remnant gastric lumens immediately before GI reconstruction, indicating a possible cellular source of PM after curative gastrectomy for GC. Dissemination of gastric contents into the peritoneal cavity should be avoided during GI reconstruction.

  17. ASCA observations of the Large Magellanic Cloud supernova remnant sample: Typing supernovae from their remnants

    NASA Technical Reports Server (NTRS)

    Hughes, John P.; Hayashi, Ichizo; Helfand, David; Hwang, Una; Itoh, Masayuki; Kirshner, Robert; Koyama, Katsuji; Markert, Thomas; Tsunemi, Hiroshi; Woo, Jonathan

    1995-01-01

    We present our first results from a study of the supernova remnants (SNRs) in the Large Magellanic Cloud (LMC) using data from ASCA. The three remnants we have analyzed to date, 0509-67.5, 0519-69.0, and N103B, are among the smallest, and presumably also the youngest, in the Cloud. The X-ray spectra of these SNRs show strong K alpha emission lines of silicon, sulfur, argon, and calcium with no evidence for corresponding lines of oxygen, neon, or magnesium. The dominant feature in the spectra is a broad blend of emission lines around 1 keV which we attribute to L-shell emission lines of iron. Model calculations (Nomoto, Thielemann, & Yokoi 1984) show that the major products of nucleosynthesis in Type Ia supernovae (SNs) are the elements from silicon to iron, as observed here. The calculated nucleosynthetic yields from Type Ib and II SNs are shown to be qualitatively inconsistent with the data. We conclude that the SNs which produced these remnants were of Type Ia. This finding also confirms earlier suggestions that the class of Balmer-dominated remnants arise from Type Ia SN explosions. Based on these early results from the LMC SNR sample, we find that roughly one-half of the SNRs produced in the LMC within the last approximately 1500 yr came from Type Ia SNs.

  18. GBT Observations of Radio Recombination Line Emission Associated with Supernova Remnants W28 and W44

    NASA Astrophysics Data System (ADS)

    Hewitt, John W.; Yusef-Zadeh, F.

    2006-06-01

    Since the 1970's weak radio recombination line(RRL) emission has been observed toward several supernova remnants. It has remained unclear if this emission is in fact associated with these remnants or due to intervening sources such as extended HII envelopes along the line of sight. To explore the origin of this emitting gas we have recently undertaken Green Bank Telescope (GBT) observations of prominent supernova remnants W28 and W44 which are well-known to be interacting with molecular clouds. Eight alpha and beta RRL transitions were mapped at C-Band (4-6 GHz) with 2.5' resolution. Maps cover 0.5 and 0.25 square degrees of W28 and W44, respectively, permitting comparison with the distribution of X-rays, Radio, and H-alpha emission. Both remnants are observed to have a mixed-morphology: a radio-continuum shell centrally-filled by thermal X-rays. We find the observed velocity of RRL emission is near the systemic velocity of both remnants as traced by OH(1720 MHz) masers. Preliminary results are presented exploring the association of the RRL-emitting gas with these interacting supernova remants and implications for the origins of the hot thermal X-ray plasma that fills their centers. Support for this work was provided by the NSF through The GBT Student Support Program from the NRAO.

  19. Fermi-LAT Observations of Supernova Remnants Kesteven 79

    NASA Astrophysics Data System (ADS)

    Auchettl, Katie; Slane, Patrick; Castro, Daniel

    2014-03-01

    In this paper, we report on the detection of γ-ray emission coincident with the Galactic supernova remnant (SNR) Kesteven 79 (Kes 79). We analyzed approximately 52 months of data obtained with the Large Area Telescope on board the Fermi Gamma-ray Space Telescope. Kes 79 is thought to be interacting with adjacent molecular clouds, based on the presence of strong 12CO J = 1 → 0 and HCO+ J = 1 → 0 emission and the detection of 1720 MHz line emission toward the east of the remnant. Acceleration of cosmic rays is expected to occur at SNR shocks, and SNRs interacting with dense molecular clouds provide a good testing ground for detecting and analyzing the production of γ-rays from the decay of π0 into two γ-ray photons. This analysis investigates γ-ray emission coincident with Kes 79, which has a detection significance of ~7σ. Additionally, we present an investigation of the spatial and spectral characteristics of Kes 79 using multiple archival XMM-Newton observations of this remnant. We determine the global X-ray properties of Kes 79 and estimate the ambient density across the remnant. We also performed a similar analysis for Galactic SNR Kesteven 78 (Kes 78), but due to large uncertainties in the γ-ray background model, no conclusion can be made about an excess of GeV γ-ray associated with the remnant.

  20. PROBING X-RAY ABSORPTION AND OPTICAL EXTINCTION IN THE INTERSTELLAR MEDIUM USING CHANDRA OBSERVATIONS OF SUPERNOVA REMNANTS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Foight, Dillon R.; Slane, Patrick O.; Güver, Tolga

    We present a comprehensive study of interstellar X-ray extinction using the extensive Chandra supernova remnant (SNR) archive and use our results to refine the empirical relation between the hydrogen column density and optical extinction. In our analysis, we make use of the large, uniform data sample to assess various systematic uncertainties in the measurement of the interstellar X-ray absorption. Specifically, we address systematic uncertainties that originate from (i) the emission models used to fit SNR spectra; (ii) the spatial variations within individual remnants; (iii) the physical conditions of the remnant such as composition, temperature, and non-equilibrium regions; and (iv) themore » model used for the absorption of X-rays in the interstellar medium. Using a Bayesian framework to quantify these systematic uncertainties, and combining the resulting hydrogen column density measurements with the measurements of optical extinction toward the same remnants, we find the empirical relation N {sub H} = (2.87 ± 0.12) × 10{sup 21} A {sub V} cm{sup 2}, which is significantly higher than the previous measurements.« less

  1. Constraints on black hole remnants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Giddings, S.B.

    1994-01-15

    One possible fate of information lost to black holes is its preservation in black hole remnants. It is argued that a type of effective field theory describes such remnants (generically referred to as informons). The general structure of such a theory is investigated and the infinite pair production problem is revisited. A toy model for remnants clarifies some of the basic issues; in particular, infinite remnant production is not suppressed simply by the large internal volumes as proposed in cornucopion scenarios. Criteria for avoiding infinite production are stated in terms of couplings in the effective theory. Such instabilities remain amore » problem barring what would be described in that theory as a strong coupling conspiracy. The relation to Euclidean calculations of cornucopion production is sketched, and potential flaws in that analysis are outlined. However, it is quite plausible that pair production of ordinary black holes (e.g., Reissner-Noerdstrom or others) is suppressed due to strong effective couplings. It also remains an open possibility that a microsopic dynamics can be found yielding an appropriate strongly coupled effective theory of neutral informons without infinite pair production.« less

  2. A Study of Supernova Remnants with Center-Filled X-Ray Morphology

    NASA Technical Reports Server (NTRS)

    Slane, Patrick O.

    1997-01-01

    CTA 1 is a center-filled supernova remnant (SNR) whose morphology and spectrum indicate the presence of a central pulsar, a synchrotron nebula, and a thermal component associated with the expansion of the blast wave into the interstellar medium. The centrally bright emission surrounds the position of a faint point source of x-rays observed with the ROSAT PSPC. Here we report on ASCA observations that confirm the nonthermal nature of the diffuse emission from the central regions of the remnant. We also present evidence for weak thermal emission that appears to increase in strength toward the outer boundary of the SNR. Thus, CTA 1 appears to be an x-ray composite remnant. Both the aftermath of the explosive supernova event and the energetic compact core are observable.

  3. The XMM-Newton view of the non-thermal supernova remnant HESS J1731-347

    NASA Astrophysics Data System (ADS)

    Puehlhofer, G.; Doroshenko, V.; Acero, F.; Bamba, A.; Klochkov, D.; Tian, W.

    2017-10-01

    HESS J1731-347 belongs to a small group of supernova remnants that are characterized by a spatially-resolved shell-type TeV morphology and strong synchrotron X-ray emission. We report on XMM-Newton observations of the source that provide for the first time a complete X-ray view of the remnant. The data show an emissivity gradient across the source, which is not observed in the TeV gamma-ray and radio bands. While the broadband spectral analysis is compatible with a pure leptonic emission scenario up to TeV energies, the morphological analysis could be indicative of a blend of hadronic and leptonic TeV emission. We discuss the possibility of an interaction of the supernova remnant with nearby molecular clouds.

  4. NASA and Japanese X-ray observatories Clarify Origin of Cosmic Rays

    NASA Technical Reports Server (NTRS)

    2005-01-01

    Recent observations from NASA and Japanese X-ray observatories have helped clarify one of the long-standing mysteries in astronomy -- the origin of cosmic rays. This image from Japan's Suzaku X-ray observatory shows RXJ1713.7-3946. This supernova remnant is the gaseous remnant of a massive star that exploded. The remnant is about 1,600 years old. The contour lines show where gamma-ray intensity is highest, as measured by the High Energy Stereoscopic System (HESS) in Namibia.

  5. Recovery of vestibular function following hair cell destruction by streptomycin

    NASA Technical Reports Server (NTRS)

    Jones, T. A.; Nelson, R. C.

    1992-01-01

    Can the vestibular periphery of warm-blooded vertebrates recover functionally from severe sensory hair cell loss? Recent findings in birds suggest a mechanism for recovery but in fact no direct functional evidence has been reported. We produced vestibular hair cell lesions using the ototoxic agent streptomycin sulfate (600 mg/kg/day, 8 days, chicks, Gallus domesticus). Compound action potentials of the vestibular nerve were used as a direct measure of peripheral vestibular function. Vestibular thresholds, neural activation latencies and amplitudes were documented. Eight days of drug treatment elevated thresholds significantly (P < 0.001) and eliminated all but remnants of vestibular activity. Virtually complete physiological recovery occurred in all animals studied over a period of 70 days following treatment. Thresholds recovered within two weeks of drug treatment whereas the return of response morphologies including activation latencies and amplitudes required an additional 6-8 weeks.

  6. Reconstructing Ancient Forms of Life

    NASA Technical Reports Server (NTRS)

    Benner, Steven A.

    1998-01-01

    Progress in the past three months has occurred in two areas, reconstruction of ancestral proteins and improved understanding of chemical features that are likely to be universal in generic matter regardless of its genesis. Ancestral ribonucleases have been reconstructed, and an example has been developed that shows how physiological function can be assigned to in vitro behaviors observed in biological systems. Sequence data have been collected to permit the reconstruction of src homology 2 domains that underwent radiative divergence at the time of the radiative divergence of chordates. New studies have been completed that show how genetic matter (or its remnants) might be detected on Mars (or other non-terrean locations.) Last, the first in vitro selection experiments have been completed using a nucleoside library carrying positively charged functionality, illustrating the importance of non-standard nucleotides to those attempting to obtain evidence for an "RNA world" as an early episode of life on earth.

  7. The emergence of Applied Physiology within the discipline of Physiology.

    PubMed

    Tipton, Charles M

    2016-08-01

    Despite the availability and utilization of the physiology textbooks authored by Albrecht von Haller during the 18th century that heralded the modern age of physiology, not all physicians or physiologists were satisfied with its presentation, contents, or application to medicine. Initial reasons were fundamental disagreements between the "mechanists," represented by Boerhaave, Robinson, and von Haller, and the "vitalists," represented by the faculty and graduates of the Montpellier School of Medicine in France, notably, Bordeu and Barthez. Subsequently, objections originated from Europe, United Kingdom, and the United States in publications that focused not only on the teaching of physiology to medical and secondary students, but on the specific applications of the content of physiology to medicine, health, hygiene, pathology, and chronic diseases. At the turn of the 20th century, texts began to appear with applied physiology in their titles and in 1926, physician Samson Wright published a textbook entitled Applied Physiology that was intended for both medical students and the medical profession. Eleven years later, physicians Best and Taylor published The Physiological Basis of Medical Practice: A University of Toronto Texbook in Applied Physiology Although both sets of authors defined the connection between applied physiology and physiology, they failed to define the areas of physiology that were included within applied physiology. This was accomplished by the American Physiological Society (APS) Publications Committee in 1948 with the publication of the Journal of Appplied Physiology, that stated the word "applied" would broadly denote human physiology whereas the terms stress and environment would broadly include work, exercise, plus industrial, climatic and social factors. NIH established a study section (SS) devoted to applied physiology in 1964 which remained active until 2001 when it became amalgamated into other SSs. Before the end of the 20th century when departments were changing their titles to reflect a stronger science orientation, many established laboratories and offered degree programs devoted to Applied Physiology. We concluded that Applied Physiology has been an important contributor to the discipline of physiology while becoming an integral component of APS. Copyright © 2016 the American Physiological Society.

  8. Interactive Effects of Large- and Small-Scale Sources of Feral Honey-Bees for Sunflower in the Argentine Pampas

    PubMed Central

    Sáez, Agustín; Sabatino, Malena; Aizen, Marcelo A.

    2012-01-01

    Pollinators for animal pollinated crops can be provided by natural and semi-natural habitats, ranging from large vegetation remnants to small areas of non-crop land in an otherwise highly modified landscape. It is unknown, however, how different small- and large-scale habitat patches interact as pollinator sources. In the intensively managed Argentine Pampas, we studied the additive and interactive effects of large expanses (up to 2200 ha) of natural habitat, represented by untilled isolated “sierras”, and narrow (3–7 m wide) strips of semi-natural habitat, represented by field margins, as pollinator sources for sunflower (Helianthus annus). We estimated visitation rates by feral honey-bees, Apis mellifera, and native flower visitors (as a group) at 1, 5, 25, 50 and 100 m from a field margin in 17 sunflower fields 0–10 km distant from the nearest sierra. Honey-bees dominated the pollinator assemblage accounting for >90% of all visits to sunflower inflorescences. Honey-bee visitation was strongly affected by proximity to the sierras decreasing by about 70% in the most isolated fields. There was also a decline in honey-bee visitation with distance from the field margin, which was apparent with increasing field isolation, but undetected in fields nearby large expanses of natural habitat. The probability of observing a native visitor decreased with isolation from the sierras, but in other respects visitation by flower visitors other than honey-bees was mostly unaffected by the habitat factors assessed in this study. Overall, we found strong hierarchical and interactive effects between the study large and small-scale pollinator sources. These results emphasize the importance of preserving natural habitats and managing actively field verges in the absence of large remnants of natural habitat for improving pollinator services. PMID:22303477

  9. Interactive effects of large- and small-scale sources of feral honey-bees for sunflower in the Argentine Pampas.

    PubMed

    Sáez, Agustín; Sabatino, Malena; Aizen, Marcelo A

    2012-01-01

    Pollinators for animal pollinated crops can be provided by natural and semi-natural habitats, ranging from large vegetation remnants to small areas of non-crop land in an otherwise highly modified landscape. It is unknown, however, how different small- and large-scale habitat patches interact as pollinator sources. In the intensively managed Argentine Pampas, we studied the additive and interactive effects of large expanses (up to 2200 ha) of natural habitat, represented by untilled isolated "sierras", and narrow (3-7 m wide) strips of semi-natural habitat, represented by field margins, as pollinator sources for sunflower (Helianthus annus). We estimated visitation rates by feral honey-bees, Apis mellifera, and native flower visitors (as a group) at 1, 5, 25, 50 and 100 m from a field margin in 17 sunflower fields 0-10 km distant from the nearest sierra. Honey-bees dominated the pollinator assemblage accounting for >90% of all visits to sunflower inflorescences. Honey-bee visitation was strongly affected by proximity to the sierras decreasing by about 70% in the most isolated fields. There was also a decline in honey-bee visitation with distance from the field margin, which was apparent with increasing field isolation, but undetected in fields nearby large expanses of natural habitat. The probability of observing a native visitor decreased with isolation from the sierras, but in other respects visitation by flower visitors other than honey-bees was mostly unaffected by the habitat factors assessed in this study. Overall, we found strong hierarchical and interactive effects between the study large and small-scale pollinator sources. These results emphasize the importance of preserving natural habitats and managing actively field verges in the absence of large remnants of natural habitat for improving pollinator services.

  10. Crustal structure of the Ionian basin and eastern Sicily margin : results from a wide angle seismic survey and implication for the crustal nature and origin of the basin, and the recent tear fault location

    NASA Astrophysics Data System (ADS)

    Gutscher, M. A.; Dellong, D.; Klingelhoefer, F.; Kopp, H.; Graindorge, D.; Margheriti, L.; Moretti, M.

    2017-12-01

    In the Ionian Sea (Central Mediterranean) the slow convergence between Africa and Eurasia results in the formation of a narrow subduction zone. The nature of the crust and lithosphere of the subducting plate remain debated and could represent the last remnants of the Neo-Tethys ocean. The rifting mechanism that produced the Ionian basin are also still under discussion with the Malta escarpment representing a possible remnant of this opening. At present, this subduction is still retreating to the south-east (motion occurring since the last 35 Ma) but is confined to the narrow Ionian Basin. In order to accommodate slab roll-back, a major lateral slab tear fault is required. This fault is thought to propagate along the eastern Sicily margin but its precise location remains controversial. This study focuses on the deep crustal structure of the Eastern-Sicily margin and the Malta Escarpment by presenting two wide-angle velocity profiles crossing these structures roughly orthogonally. The data used for the forward velocity modeling were acquired onboard the R/V Meteor during the DIONYSUS cruise in 2014. The results image an oceanic crust within the Ionian basin as well as the deep structure of the Malta Escarpment which presents characteristics of a transform margin. A deep and asymmetrical sedimentary basin is imaged south of the Messina strait and seems to have opened in between the Calabrian and Peloritan continental terranes. The interpretation of the velocity models suggests that the tear fault is located east of the Malta Escarpment, along the Alfeo fault system.

  11. Orbital dynamics in galaxy mergers

    NASA Astrophysics Data System (ADS)

    Hoffman, Loren

    In the favored vacuum energy + cold dark matter (ACDM) cosmology, galaxies form through a hierarchical merging process. Mergers between comparable-mass sys tems are qualitatively different from the ongoing accretion of small objects by much larger ones, in that they can radically transform the nature of the merging objects, e.g. through violent relaxation of the stars and dark matter, triggered starbursts, and quasar activity. This thesis covers two phenomena unique to major galaxy mergers: the formation of supermassive black hole (SMBH) binary and triple systems, and the transformation of the stellar orbit structure through violent relaxation, triggered gas inflow, and star formation. In a major merger, the SMBHs can spiral in and form a bound binary in less than a Hubble time. If the binary lifetime exceeds the typical time between mergers, then triple black hole (BH) systems may form. We study the statistics of close triple-SMBH encounters in galactic nuclei by computing a series of three-body orbits with physically-motivated initial conditions appropriate for giant elliptical galaxies. Our simulations include a smooth background potential consisting of a stellar bulge plus a dark matter halo, drag forces due to gravitational radiation and dynamical friction on the stars and dark matter, and a simple model of the time evolution of the inner density profile under heating and mass ejection by the SMBHs. We find that the binary pair coalesces as a result of repeated close encounters in ~85% of our runs. In about 40% of the runs the lightest BH is left wandering through the galactic halo or escapes the galaxy altogether. The triple systems typically scour out cores with mass deficits ~1-2 times their total mass. The high coalescence rate and prevalence of very high-eccentricity orbits could provide interesting signals for the future Laser Interferometer Space Antenna (LISA). Our study of remnant orbit structure involved 42 disk-disk mergers at various gas fractions, and 10 re-mergers of the 40% gas remnants. All simulations were run using a version of GADGET-2 [173] that included subresolution models of radiative cooling, star formation, and supernova and AGN feedback. The potential was frozen at the last snapshot of each simulation and the orbits of ~50,000 randomly chosen stars were integrated for ~100 dynamical times, and classified based on their Fourier spectra using the algorithm of [30]. The 40% gas remnants were found to be dominated by minor-axis tube orbits in their inner regions, whereas box orbits were the dominant orbit family in the inner parts of the dissipationless disk-disk and remnant-remnant systems. The phase space available to minor-axis tube orbits in even the 5% gas remnants was much larger than that in the dissipationless remnants, but the 5% gas remnants are not fast rotators because these orbits tend to be isotropically distributed at low gas fractions. Some of the remnants show significant minor axis rotation, due to large orientation twists in their outer parts (in the 40% gas remnants) and asymmetrically rotating major-axis tube orbits throughout the remnants (in the re-mergers).

  12. Ontology of physics for biology: representing physical dependencies as a basis for biological processes.

    PubMed

    Cook, Daniel L; Neal, Maxwell L; Bookstein, Fred L; Gennari, John H

    2013-12-02

    In prior work, we presented the Ontology of Physics for Biology (OPB) as a computational ontology for use in the annotation and representations of biophysical knowledge encoded in repositories of physics-based biosimulation models. We introduced OPB:Physical entity and OPB:Physical property classes that extend available spatiotemporal representations of physical entities and processes to explicitly represent the thermodynamics and dynamics of physiological processes. Our utilitarian, long-term aim is to develop computational tools for creating and querying formalized physiological knowledge for use by multiscale "physiome" projects such as the EU's Virtual Physiological Human (VPH) and NIH's Virtual Physiological Rat (VPR). Here we describe the OPB:Physical dependency taxonomy of classes that represent of the laws of classical physics that are the "rules" by which physical properties of physical entities change during occurrences of physical processes. For example, the fluid analog of Ohm's law (as for electric currents) is used to describe how a blood flow rate depends on a blood pressure gradient. Hooke's law (as in elastic deformations of springs) is used to describe how an increase in vascular volume increases blood pressure. We classify such dependencies according to the flow, transformation, and storage of thermodynamic energy that occurs during processes governed by the dependencies. We have developed the OPB and annotation methods to represent the meaning-the biophysical semantics-of the mathematical statements of physiological analysis and the biophysical content of models and datasets. Here we describe and discuss our approach to an ontological representation of physical laws (as dependencies) and properties as encoded for the mathematical analysis of biophysical processes.

  13. Detail, corner pilaster remnant, gable return on facade, Our Corner ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail, corner pilaster remnant, gable return on facade, Our Corner Saloon, view to northeast (210mm lens with electronic flash fill) - Our Corner Saloon, 301 First Street, Eureka, Humboldt County, CA

  14. Optical emission from a fast shock wave - The remnants of Tycho's supernova and SN 1006

    NASA Technical Reports Server (NTRS)

    Chevalier, R. A.; Raymond, J. C.

    1978-01-01

    The faint optical filaments in Tycho's supernova remnant appear to be emission from a shock front moving at 5600 km/s. The intensity of the hydrogen lines, the absence of forbidden lines of heavy elements in the spectrum, and the width of the filaments are explained by a model in which a collisionless shock wave is moving into partially neutral gas. The presence of the neutral gas can be used to set an upper limit of approximately 5 x 10 to the 47th power ergs to the energy in ionizing radiation emitted by a Type I supernova. The patchy neutral gas is probably part of the warm neutral component of the interstellar medium. The existing information on the remnant of SN 1006 indicates that its emission is similar in nature to that from Tycho's remnant.

  15. A HIRES analysis of the FIR emission of supernova remnants

    NASA Technical Reports Server (NTRS)

    Wang, Zhong

    1994-01-01

    The high resolution (HiRes) algorithm has been used to analyze the far infrared emission of shocked gas and dust in supernova remnants. In the case of supernova remnant IC 443, we find a very good match between the resolved features in the deconvolved images and the emissions of shocked gas mapped in other wavelengths (lines of H2, CO, HCO+, and HI). Dust emission is also found to be surrounding hot bubbles of supernova remnants which are seen in soft X-ray maps. Optical spectroscopy on the emission of the shocked gas suggests a close correlation between the FIR color and local shock speed, which is a strong function of the ambient (preshock) gas density. These provide a potentially effective way to identify regions of strong shock interaction, and thus facilitate studies of kinematics and energetics in the interstellar medium.

  16. Small intestinal obstruction by remnants of the omphalomesenteric duct: findings on contrast enema.

    PubMed

    Fenton, L Z; Buonomo, C; Share, J C; Chung, T

    2000-03-01

    We reviewed the contrast enema examinations and medical records of six patients with small intestinal obstruction due to omphalomesenteric duct remnant to evaluate for characteristic imaging findings. In five out of the six patients the point of obstruction was demonstrated on the enema; in three patients, the characteristic "beak" of a volvulus was seen, either in the terminal ileum or cecum. In three patients, there was medial deviation of the cecum. The characteristic radiographic features of volvulus at the cecum or terminal ileum and medial deviation of the cecum should suggest persistence of an omphalomesenteric duct remnant as the etiology of obstruction in a child less than 2 years of age. The appearance of omphalomesenteric duct remnant obstruction on enema examination, though not specific, is characteristic and should be familiar to pediatric radiologists.

  17. On the search for Galactic supernova remnant PeVatrons with current TeV instruments

    NASA Astrophysics Data System (ADS)

    Cristofari, P.; Gabici, S.; Terrier, R.; Humensky, T. B.

    2018-06-01

    The supernova remnant hypothesis for the origin of Galactic cosmic rays has passed several tests, but the firm identification of a supernova remnant pevatron, considered to be a decisive step to prove the hypothesis, is still missing. While a lot of hope has been placed in next-generation instruments operating in the multi-TeV range, it is possible that current gamma-ray instruments, operating in the TeV range, could pinpoint these objects or, most likely, identify a number of promising targets for instruments of next generation. Starting from the assumption that supernova remnants are indeed the sources of Galactic cosmic rays, and therefore must be pevatrons for some fraction of their lifetime, we investigate the ability of current instruments to detect such objects, or to identify the most promising candidates.

  18. A Newly Discovered Supernova Remnant and MSH 11-62 and 3C58

    NASA Technical Reports Server (NTRS)

    Slane, Patrick O.

    2000-01-01

    CTA 1 is a center-filled supernova remnant (SNR) whose morphology and spectrum indicate the presence of a central pulsar, a synchrotron nebula, and a thermal component associated with the expansion of the blast wave into the interstellar medium. The centrally bright emission surrounds the position of a faint point source of X-rays observed with the ROSAT Position Sensitive Proportional Counter (PSPC). Here we report on Advanced Spacecraft for Cosmology Astrophysics (ASCA) observations that confirm the nonthermal nature of the diffuse emission from the central regions of the remnant. We also present evidence for weak thermal emission that appears to increase in strength toward the outer boundary of the SNR. Thus, CTA 1 appears to be an X-ray composite remnant. Both the aftermath of the explosive supernova event and the energetic compact core are observable.

  19. Temperature relaxation in supernova remnants, revisited

    NASA Technical Reports Server (NTRS)

    Itoh, H.

    1984-01-01

    Some supernova remnants are expanding into a partially neutral medium. The neutral atoms which are engulfed by the fast blast shock are collisionally ionized to eject low-energy secondary electrons. Calculations are conducted of the temperature relaxation through Coulomb collisions among the secondary electrons, the shocked electrons, and the ions, assuming that the three species have Maxwellian velocity distributions. The results are applied to a self-similar blast wave. If the efficiency of collisionless electron heating at the shock front is high in young remnants such as Tycho, the secondary electrons may be much cooler than both the shocked electrons and the ions. In this case, the emergent X-ray continuum spectrum will have a two-temperature, or a power-law, appearance. This effect may have been observed in the bright rim of the remnant of SN 1006.

  20. The Spin Evolution of Fast-rotating, Magnetized Super-Chandrasekhar White Dwarfs in the Aftermath of White Dwarf Mergers

    NASA Astrophysics Data System (ADS)

    Becerra, L.; Rueda, J. A.; Lorén-Aguilar, P.; García-Berro, E.

    2018-04-01

    The evolution of the remnant of the merger of two white dwarfs is still an open problem. Furthermore, few studies have addressed the case in which the remnant is a magnetic white dwarf with a mass larger than the Chandrasekhar limiting mass. Angular momentum losses might bring the remnant of the merger to the physical conditions suitable for developing a thermonuclear explosion. Alternatively, the remnant may be prone to gravitational or rotational instabilities, depending on the initial conditions reached after the coalescence. Dipole magnetic braking is one of the mechanisms that can drive such losses of angular momentum. However, the timescale on which these losses occur depends on several parameters, like the strength of the magnetic field. In addition, the coalescence leaves a surrounding Keplerian disk that can be accreted by the newly formed white dwarf. Here we compute the post-merger evolution of a super-Chandrasekhar magnetized white dwarf taking into account all the relevant physical processes. These include magnetic torques acting on the star, accretion from the Keplerian disk, the threading of the magnetic field lines through the disk, and the thermal evolution of the white dwarf core. We find that the central remnant can reach the conditions suitable to develop a thermonuclear explosion before other instabilities (such as the inverse beta-decay instability or the secular axisymmetric instability) are reached, which would instead lead to gravitational collapse of the magnetized remnant.

  1. THE ABSENCE OF EX-COMPANIONS IN TYPE Ia SUPERNOVA REMNANTS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Di Stefano, R.; Kilic, Mukremin, E-mail: rd@cfa.harvard.edu, E-mail: kilic@ou.edu

    Type Ia supernovae (SNe Ia) play important roles in our study of the expansion and acceleration of the universe, but because we do not know the exact nature or natures of the progenitors, there is a systematic uncertainty that must be resolved if SNe Ia are to become more precise cosmic probes. No progenitor system has ever been identified either in the pre- or post-explosion images of a Ia event. There have been recent claims for and against the detection of ex-companion stars in several SNe Ia remnants. These studies, however, usually ignore the angular momentum gain of the progenitormore » white dwarf (WD), which leads to a spin-up phase and a subsequent spin-down phase before explosion. For spin-down timescales greater than 10{sup 5} years, the donor star could be too dim to detect by the time of explosion. Here we revisit the current limits on ex-companion stars to SNR 0509-67.5, a 400-year-old remnant in the Large Magellanic Cloud. If the effects of possible angular momentum gain on the WD are included, a wide range of single-degenerate progenitor models are allowed for this remnant. We demonstrate that the current absence of evidence for ex-companion stars in this remnant, as well as other SNe Ia remnants, does not necessarily provide the evidence of absence for ex-companions. We discuss potential ways to identify such ex-companion stars through deep imaging observations.« less

  2. The many sides of RCW 86: a Type Ia supernova remnant evolving in its progenitor's wind bubble

    NASA Astrophysics Data System (ADS)

    Broersen, Sjors; Chiotellis, Alexandros; Vink, Jacco; Bamba, Aya

    2014-07-01

    We present the results of a detailed investigation of the Galactic supernova remnant RCW 86 using the XMM-Newton X-ray telescope. RCW 86 is the probable remnant of SN 185 A.D., a supernova that likely exploded inside a wind-blown cavity. We use the XMM-Newton Reflection Grating Spectrometer to derive precise temperatures and ionization ages of the plasma, which are an indication of the interaction history of the remnant with the presumed cavity. We find that the spectra are well fitted by two non-equilibrium ionization models, which enables us to constrain the properties of the ejecta and interstellar matter plasma. Furthermore, we performed a principal component analysis on EPIC MOS and pn data to find regions with particular spectral properties. We present evidence that the shocked ejecta, emitting Fe K and Si line emission, are confined to a shell of approximately 2 pc width with an oblate spheroidal morphology. Using detailed hydrodynamical simulations, we show that general dynamical and emission properties at different portions of the remnant can be well reproduced by a Type Ia supernova that exploded in a non-spherically symmetric wind-blown cavity. We also show that this cavity can be created using general wind properties for a single degenerate system. Our data and simulations provide further evidence that RCW 86 is indeed the remnant of SN 185, and is the likely result of a Type Ia explosion of single degenerate origin.

  3. Measuring Physician Cognitive Load: Validity Evidence for a Physiologic and a Psychometric Tool

    ERIC Educational Resources Information Center

    Szulewski, Adam; Gegenfurtner, Andreas; Howes, Daniel W.; Sivilotti, Marco L. A.; van Merriënboer, Jeroen J. G.

    2017-01-01

    In general, researchers attempt to quantify cognitive load using physiologic and psychometric measures. Although the construct measured by both of these metrics is thought to represent overall cognitive load, there is a paucity of studies that compares these techniques to one another. The authors compared data obtained from one physiologic tool…

  4. Physiology Learning for Veterinary Students: Impact of Guided Practices on Students' Opinion and Physiological Parameters

    ERIC Educational Resources Information Center

    García-Vázquez, Francisco A.; Romar, Raquel; Gadea, Joaquín; Matás, Carmen; Coy, Pilar; Ruiz, Salvador

    2018-01-01

    Over recent decades, education has increasingly focused on student-centered learning. Guided practices represent a new way of learning for undergraduate students of physiology, whereby the students turn into teacher-students and become more deeply involved in the subject by preparing and teaching a practical (laboratory) class to their peers. The…

  5. On the geological origin of Devils Tower (WY, USA)

    NASA Astrophysics Data System (ADS)

    Zavada, P.; Dedecek, P.; Holloway, S. D.; Chang, J. C.; Crain, K.; Keller, G. R.

    2011-12-01

    The Devils Tower is an exceptional igneous rock formation and a dominating landmark of the northern plains in Wyoming (USA). It rises 250 m above the surrounding sedimentary formations. Previous hypotheses suggested that the Devils Tower was originally part of a magmatic intrusion; volcanic conduit, magmatic stock or a laccolith. Our review of the geological evidence suggests that the Devils Tower is a remnant of an eroded lava lake that filled a broad phreatomagmatic volcano crater. Our hypothesis is based on a detailed study of a similar phonolite landmark in Czech Republic, called Boren, and analogue modeling, finite element numerical modeling of cooling for various shapes of volcanic bodies, and results of field and gravity surveys of the area. The Devils Tower together with a group of five phonolite bodies called Missouri Buttes, located 6 km NW from the Devils Tower, represent the easternmost products of the Tertiary tectonomagmatic events related to the lithospheric-scale uplift of the Black hills monocline. The phreatomagmatic deposits in the surroundings of the Missouri Buttes and the Devils Tower suggest that these phonolite bodies were originally emplaced into phreatomagmatic maar-diatreme volcanoes. To reveal the original shape of the Devils Tower, we employed the analogue modeling using plaster of Paris as analogue for phonolite magma to study internal fabrics and shapes of extrusive/intrusive magmatic bodies emplaced into the maar-diatreme volcanoes. Then, the resulting shapes of analogue magmatic bodies were used for the Finite Element thermal numerical models of their cooling using the thermophysical parameters of the phonolite magma and the rock units surrounding the Devils Tower and Missouri Buttes. Because the columnar joints grow perpendicular to the isotherms in cooling igneous and volcanic bodies, we analyzed the match between the thermal structure of the FE models and the columnar jointing pattern on the Devils Tower. The best fit of the thermal structure and the inverted fan columnar jointing pattern on Devils Tower was found for one of the models that produced a lava lake filling the entire maar crater of the phreatomagmatic volcano. The Devils Tower represents the central part of the lake just above the feeding conduit. After emplacement and solidification of the lava lake, erosion first removed the weakly consolidated phreatomagmatic deposits in the tuff ring around the lake. Then the lava body eroded laterally due to the formation of ice in the columnar joints, pushing columns away from the neighboring columns into the open space. The remnant of the solidified lake (Devils Tower) represents a structure, which is resistant to this kind of erosion, because its base is formed by columns that lean against each other and towards the center of the Tower. In contrast, the Missouri Buttes most probably represent a remnant of a branched intrusion producing several extrusive domes on the maar-crater periphery that can form by subsequent emplacement of different magma batches (e.g. from a stratified magma chamber), each with relatively lower yield strength owing to decreasing crystal content.

  6. Limits on coronal material in normal galaxies

    NASA Technical Reports Server (NTRS)

    Mccammon, D.

    1986-01-01

    Measurements of the X-ray surface brightness of a face on disk galaxy M101, have previously been used to place upper limits on the power radiated by a hot corona. Such analysis contrains the effective density of the disk; either it must be so low that the remnants drive a fast hot wind (low radiated power) or so high that the remnant temperature at overlap is low (low X-ray power). These X-ray measurements are here used to constrain the properties of the population of supernova remnants evolving in the disk. This adds a further constraint since young remnants evolving in higher density radiate more of their energy in X-rays, whether or not they eventually overlap to generate a hot corona. The strength of this second limit depends strongly on the density history of the remnants and on the assumed supernova rate. For evaporative evolution the analysis rules out McKee and Ostriker ISM model in particular and evaporative evolution in general unless the supernova rate is at least several times lower than current expectations. For standard Sedov evolutions, the density limit marginally admits evolution in 0.2 cu m, a popular alternative to the McKee and Ostriker model.

  7. Imprints of neutrino-pair flavor conversions on nucleosynthesis in ejecta from neutron-star merger remnants

    NASA Astrophysics Data System (ADS)

    Wu, Meng-Ru; Tamborra, Irene; Just, Oliver; Janka, Hans-Thomas

    2017-12-01

    The remnant of neutron star mergers is dense in neutrinos. By employing inputs from one hydrodynamical simulation of a binary neutron star merger remnant with a black hole of 3 M⊙ in the center, dimensionless spin parameter 0.8 and an accretion torus of 0.3 M⊙, the neutrino emission properties are investigated as the merger remnant evolves. Initially, the local number density of ν¯e is larger than that of νe everywhere above the remnant. Then, as the torus approaches self-regulated equilibrium, the local abundance of neutrinos overcomes that of antineutrinos in a funnel around the polar region. The region where the fast pairwise flavor conversions can occur shrinks accordingly as time evolves. Still, we find that fast flavor conversions do affect most of the neutrino-driven ejecta. Assuming that fast flavor conversions lead to flavor equilibration, a significant enhancement of nuclei with mass numbers A >130 is found as well as a change of the lanthanide mass fraction by more than a factor of a thousand. Our findings hint towards a potentially relevant role of neutrino flavor oscillations for the prediction of the kilonova (macronova) light curves and motivate further work in this direction.

  8. Modelling Hard Gamma-Ray Emission from Supernova Remnants

    NASA Technical Reports Server (NTRS)

    Baring, Matthew

    2000-01-01

    The observation by the CANGAROO experiment of TeV emission from SN 1006, in conjunction with several instances of non-thermal X-ray emission from supernova remnants, has led to inferences of super-TeV electrons in these extended sources. While this is sufficient to propel the theoretical community in their modelling of particle acceleration and associated radiation, the anticipated emergence in the next decade of a number of new experiments probing the TeV and sub-TeV bands provides further substantial motivation for modellers. In particular, the quest for obtaining unambiguous gamma-ray signatures of cosmic ray ion acceleration defines a "Holy Grail" for observers and theorists alike. This review summarizes theoretical developments in the prediction of MeV-TeV gamma-rays from supernova remnants over the last five years, focusing on how global properties of models can impact, and be impacted by, hard gamma-ray observational programs, thereby probing the supernova remnant environment. Properties of central consideration include the maximum energy of accelerated particles, the density of the unshocked interstellar medium, the ambient magnetic field, and the relativistic electron-to-proton ratio. Criteria for determining good candidate remnants for observability in the TeV band are identified.

  9. Diced Remnant

    NASA Image and Video Library

    2006-06-05

    This MOC image shows blocky remnants of a material that was once more laterally extensive on the floor of an impact crater located northwest of Herschel Crater on Mars. Large ripples of windblown sediment have accumulated around and between the blocks

  10. Simultaneous branchial cleft and thyroid disorders may present a management challenge.

    PubMed

    Harding, Jane L; Veivers, David; Sidhu, Stan B; Sywak, Mark S; Shun, Albert; Delbridge, Leigh W

    2005-09-01

    Cysts, sinuses or abscesses arising from second, third or fourth branchial cleft remnants may lie either within the body of, or in close proximity to the thyroid gland. Given their infrequent nature they may pose both diagnostic and management challenges for the treating surgeon when they occur in association with thyroid disorders. This is a case series. All patients with concomitant thyroid disorders and a branchial cleft anomaly treated in the University of Sydney Endocrine Surgical Unit in the 10-year period 1994-2003 comprised the study group. Patient demographics, clinical presentation, imaging, surgical management, definitive histology and outcomes were documented. Six patients were identified with an age range of 3-76 years and a male : female ratio of 1:5. Five branchial cleft anomalies were left sided, one was right sided. Two patients had second cleft anomalies, both of which were initially thought to represent metastatic lymph nodes in association with thyroid cancer. A further two patients had third cleft abnormalities presenting as suppurative thyroiditis. The final two patients had fourth cleft abnormalities causing intraoperative management problems. Branchial cleft remnants and anomalies are rare but may occur in association with thyroid disease. They may pose a diagnostic and management dilemma either preoperatively, when mistaken for metastatic thyroid cancer, or intraoperatively when mistaken for a thyroid nodule.

  11. Spatial-temporal variation in orchid bee communities (Hymenoptera: Apidae) in remnants of arboreal Caatinga in the Chapada Diamantina region, state of Bahia, Brazil.

    PubMed

    Andrade-Silva, A C R; Nemésio, A; de Oliveira, F F; Nascimento, F S

    2012-08-01

    The spatial and temporal distribution of organisms is a fundamental aspect of biological communities. The present study focused on three remnants of arboreal Caatinga in northeastern Brazil between May, 2009 and April, 2010. A total of 627 euglossine males were captured in traps baited with artificial aromatic compounds. The specimens belonged to 14 species and four genera: Euglossa Latreille, Eulaema Lepeletier, Eufriesea Cockerell, and Exaerete Hoffmannsegg. Eulaema nigrita Lepeletier (41.6), Euglossa carolina Nemésio (15.3%), Eulaema marcii Nemésio (13.6%), and Euglossa melanotricha Moure (12.8%) were the most common species sampled. The distribution of collected specimens per fragment was as follows: Braúna (280 ha)--259 individuals belonging to 14 species; Cambuí (179 ha)--161 individuals from eight species; and Pindoba (100 ha)--207 individuals represented by seven species. Braúna had the highest diversity (H' = 1.91) and estimated species richness. The largest fragment was the main source of the observed variation in species richness and abundance, indicating a non-random pattern of spatial distribution. The analysis of environmental factors indicated that seasonal variation in these factors was the principal determinant of species occurrence and abundance.

  12. Effects of porosity on shock-induced melting of honeycomb-shaped Cu nanofoams

    NASA Astrophysics Data System (ADS)

    Zhao, Fengpeng

    Metallic foams are of fundamental and applied interests in various areas, including structure engineering (e.g., lightweight structural members and energy absorbers), and shock physics (e.g., as laser ablators involving shock-induced melting and vaporization).Honeycomb-shaped metallic foams consist of regular array of hexagonal cells in two dimensions and have extensive applications and represent a unique, simple yet useful model structure for exploring mechanisms and making quantitative assessment. We investigate shock-induced melting in honeycomb-shaped Cu nanofoams with extensive molecular dynamics simulations. A total of ten porosities (phi) are explored, ranging from 0 to 0.9 at an increment of 0.1. Upon shock compression, void collapse induces local melting followed by supercooling for sufficiently high porosity at low shock strengths. While superheating of solid remnants occurs for sufficiently strong shocks at phi<0.1. Both supercooling of melts and superheating of solid remnants are transient, and the equilibrated shock states eventually fall on the equilibrium melting curve for partial melting. However, phase equilibrium has not been achieved on the time scale of simulations in supercooled Cu liquid (from completely melted nanofoams). The temperatures for incipient and complete melting are related to porosity via a power law and approach the melting temperature at zero pressure as phi tends to 1.

  13. Re-Evaluating the Geological Evidence for Late Holocene Marine Incursion Events along the Guerrero Seismic Gap on the Pacific Coast of Mexico

    PubMed Central

    Bianchette, Thomas A.

    2016-01-01

    Despite the large number of tsunamis that impact Mexico’s Pacific coast, stratigraphic studies focusing on geological impacts are scanty, making it difficult to assess the long-term risks for this vulnerable region. Surface samples and six cores were taken from Laguna Mitla near Acapulco to examine sedimentological and geochemical evidence for marine incursion events. Sediment cores collected from behind the beach barrier are dominated by intercalated layers of peat and inorganic sediments, mostly silt and clay, with little or no sand. Sand- and shell-rich clastic layers with high levels of sulfur, calcium, and strontium only occur adjacent to the relict beach ridge remnants near the center of the lagoon. With the exception of one thin fine sand layer, the absence of sand in the near-shore cores and the predominance of the terrigenous element titanium in the inorganic layers, evidently eroded from the surrounding hillslopes, suggests that these large-grained intervals do not represent episodic marine incursions, but rather were likely formed by the erosion and redeposition of older marine deposits derived from the beach ridge remnants when water levels were high. These results do not support the occurrence of a large tsunami event at Laguna Mitla during the Late Holocene. PMID:27571270

  14. Phagocytosis of Giardia muris by macrophages in Peyer's patch epithelium in mice.

    PubMed

    Owen, R L; Allen, C L; Stevens, D P

    1981-08-01

    No mechanism for the initiation of immunological clearance of Giardia from the mammalian intestinal tract has been identified. In normal and nude mice experimentally infected with G. muris, we examined antigen-sampling epithelium over Peyer's patch follicles by electron microscopy for evidence of interaction between G. muris and lymphoid cells. Invading G. muris were found in the epithelium near dying or desquamating columnar cells. Macrophages beneath the basal lamina extended pseudopods into the epithelium, trapping invading G. muris and enclosing them in phagolysosomes. In normal mice, which clear G. muris in 4 to 6 weeks, macrophages containing digested G. muris were surrounded by rosettes of lymphoblasts in the epithelium. In nude mice deficient in lymphocytes, there was apparent hyperplasia of macrophages, which filled the follicle domes, resulting in more frequent entrapment of G. muris but no contact between macrophages and lymphoblasts in the epithelium. In nude mice, which require 6 months to control G. muris infection, lymphoblast contact with macrophages containing distinctive microtubular remnants of G. muris was only identified in the follicle dome. This close physical association of lymphoblasts and macrophages containing G. muris remnants suggests that this macrophage activity represents intraepithelial antigen processing as well as a defense against the effects of the uncontrolled entrance of microorganisms and other antigenic particles into Peyer's patch lymphoid follicles.

  15. Re-Evaluating the Geological Evidence for Late Holocene Marine Incursion Events along the Guerrero Seismic Gap on the Pacific Coast of Mexico.

    PubMed

    Bianchette, Thomas A; McCloskey, Terrence A; Liu, Kam-Biu

    2016-01-01

    Despite the large number of tsunamis that impact Mexico's Pacific coast, stratigraphic studies focusing on geological impacts are scanty, making it difficult to assess the long-term risks for this vulnerable region. Surface samples and six cores were taken from Laguna Mitla near Acapulco to examine sedimentological and geochemical evidence for marine incursion events. Sediment cores collected from behind the beach barrier are dominated by intercalated layers of peat and inorganic sediments, mostly silt and clay, with little or no sand. Sand- and shell-rich clastic layers with high levels of sulfur, calcium, and strontium only occur adjacent to the relict beach ridge remnants near the center of the lagoon. With the exception of one thin fine sand layer, the absence of sand in the near-shore cores and the predominance of the terrigenous element titanium in the inorganic layers, evidently eroded from the surrounding hillslopes, suggests that these large-grained intervals do not represent episodic marine incursions, but rather were likely formed by the erosion and redeposition of older marine deposits derived from the beach ridge remnants when water levels were high. These results do not support the occurrence of a large tsunami event at Laguna Mitla during the Late Holocene.

  16. Hot subdwarfs formed from the merger of two He white dwarfs

    NASA Astrophysics Data System (ADS)

    Schwab, Josiah

    2018-06-01

    We perform stellar evolution calculations of the remnant of the merger of two He white dwarfs (WDs). Our initial conditions are taken from hydrodynamic simulations of double WD mergers and the viscous disc phase that follows. We evolve these objects from shortly after the merger into their core He-burning phase, when they appear as hot subdwarf stars. We use our models to quantify the amount of H that survives the merger, finding that it is difficult for ≳ 10^{-4} M_{⊙} of H to survive, with even less being concentrated in the surface layers of the object. We also study the rotational evolution of these merger remnants. We find that mass-loss over the {˜ } 10^4 yr following the merger can significantly reduce the angular momentum of these objects. As hot subdwarfs, our models have moderate surface rotation velocities of 30-100 km s-1. The properties of our models are not representative of many apparently isolated hot subdwarfs, suggesting that those objects may form via other channels or that our modelling is incomplete. However, a sub-population of hot subdwarfs are moderate-to-rapid rotators and/or have He-rich atmospheres. Our models help to connect the observed properties of these objects to their progenitor systems.

  17. Hemiacidrin irrigations to dissolve stone remnants after nephrolithotomy. Problems with solution flow.

    PubMed

    Rodman, J S; Reckler, J M; Israel, A R

    1981-08-01

    Following surgery for branched renal calculi, hemiacidrin irrigation may be useful to dissolve any residual stones. Struvite, the mineral in these stones, is itself an alkaline buffer and can raise the pH of the irrigating solution rendering it ineffective. Large volumes of hemiacidrin must reach the stone remnants or they are unlikely to dissolve. Two cases are described in which creative positioning of the patient or the irrigation catheters was necessary to permit adequate amounts of hemiacidrin to reach and dissolve stone remnants.

  18. Surprisingly high-pressure shocks in the supernova remnant IC 443

    NASA Technical Reports Server (NTRS)

    Moorhouse, A.; Brand, P. W. J. L.; Geballe, T. R.; Burton, M. G.

    1991-01-01

    The intensities of several lines of molecular hydrogen have been measured from two regions of the supernova-remnant/molecular-cloud shock in IC 443. The lines measured have upper-state energies ranging from 7000 K to 23,000 K. Their relative intensities differ in the two regions, but are consistent with those predicted from the post-shock regions of simple jump-type shocks of different pressure. The pressures so derived are far higher than the pressure in the supernova remnant itself, and a possible reason for this discrepancy is discussed.

  19. Long term variability of the cosmic ray intensity

    NASA Technical Reports Server (NTRS)

    Bhat, C. L.; Houston, B. P.; Mayer, C. J.; Wolfendale, A. W.

    1985-01-01

    In a previous paper Bhat, et al., assess the evidence for the continuing acceleration of cosmic rays in the Loop I supernova remnant. The enhanced gamma-ray emission is found consistent with the Blandford and Cowie model for particle acceleration at the remnant shock wave. The contributions of other supernovae remnants to the galactic cosmic ray energy density are now considered, paying anisotropy of cosmic rays accelerated by local supernovae ( 100 pc). The results are compared with geophysical data on the fluctuations in the cosmic ray intensity over the previous one billion years.

  20. X-ray spectroscopic observations and modeling of supernova remnants

    NASA Technical Reports Server (NTRS)

    Shull, J. M.

    1981-01-01

    The X-ray observations of young remnants and their theoretical interpretation are described. A number of questions concerning the nature of the blast wave interaction with the interstellar gas and grains and of atomic processes in these hot plasmas are considered. It is concluded that future X-ray spectrometers with high collecting area, moderate spectral resolution and good spatial resolution can make important contributions to the understanding of supernova remnants in the Milky Way and neighboring galaxies and of their role in the global chemical and dynamical evolution of the interstellar medium.

  1. A Low-Frequency Survey of the Galactic Plane Near l = 11 degs: Discovery of Three New Supernova Remnants

    DTIC Science & Technology

    2004-01-01

    A LOW-FREQUENCY SURVEY OF THE GALACTIC PLANE NEAR l = 11: DISCOVERY OF THREE NEW SUPERNOVA REMNANTS C. L. Brogan,1,2 K. E. Devine,3,4 T. J. Lazio,5...230; Green 2002). This paucity is likely due in part to selection effects acting against the discovery of the more mature, faint, extended remnants...00-00-2004 to 00-00-2004 4. TITLE AND SUBTITLE A Low-Frequency Survey of the Galactic Plane Near l=11degrees: Discovery of Three New Supernova

  2. On the Essence of the Mind and the Object of Psychology

    DTIC Science & Technology

    1960-07-26

    a simple reflectional process. At one time, Wundt , unable to discriminate between the object of psychology and the object of physiology, intro...duced the new term "physiological psychology." As the objects of this science Wundt lists those vital processes which have an external as well as an...physiology alone." According to Wundt perception represents, on the one hand, only a psychological fact and, on the other hand, only a physiological act. It

  3. Melanopsin-mediated light-sensing in amphioxus

    PubMed Central

    del Pilar Gomez, María

    2009-01-01

    The two fundamental lineages of photoreceptor cells, microvillar and ciliary, were long thought to be a prerogative of invertebrate and vertebrate organisms, respectively. However evidence of their ancient origin, preceding the divergence of these two branches of metazoa, suggests instead that they should be ubiquitously distributed. Melanopsin-expressing ‘circadian’ light receptors may represent the remnants of the microvillar photo- receptors amongst vertebrates, but they lack the characteristic architecture of this lineage, and much remains to be clarified about their signaling mechanisms. Hesse and Joseph cells of the neuronal tube of amphioxus (Branchiostoma fl.)—the most basal chordate extant—turn out to be depolarizing primary microvillar photoreceptors, that generate a melanopsin-initiated, PLC-dependent response to light, mobilizing internal Ca and increasing a membrane conductance selective to Na and Ca ions. As such, they represent a canonical instance of invertebrate-like visual cells in the chordate phylum. PMID:19907713

  4. Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction.

    PubMed

    Jørgensen, Anders Berg; Frikke-Schmidt, Ruth; West, Anders Sode; Grande, Peer; Nordestgaard, Børge G; Tybjærg-Hansen, Anne

    2013-06-01

    Elevated non-fasting triglycerides mark elevated levels of remnant cholesterol. Using a Mendelian randomization approach, we tested whether genetically increased remnant cholesterol in hypertriglyceridaemia due to genetic variation in the apolipoprotein A5 gene (APOA5) associates with an increased risk of myocardial infarction (MI). We resequenced the core promoter and coding regions of APOA5 in individuals with the lowest 1% (n = 95) and highest 2% (n = 190) triglyceride levels in the Copenhagen City Heart Study (CCHS, n = 10 391). Genetic variants which differed in frequency between the two extreme triglyceride groups (c.-1131T > C, S19W, and c.*31C > T; P-value: 0.06 to <0.001), thus suggesting an effect on triglyceride levels, were genotyped in the Copenhagen General Population Study (CGPS), the CCHS, and the Copenhagen Ischemic Heart Disease Study (CIHDS), comprising a total of 5705 MI cases and 54 408 controls. Genotype combinations of these common variants associated with increases in non-fasting triglycerides and calculated remnant cholesterol of, respectively, up to 68% (1.10 mmol/L) and 56% (0.40 mmol/L) (P < 0.001), and with a corresponding odds ratio for MI of 1.87 (95% confidence interval: 1.25-2.81). Using APOA5 genotypes in instrumental variable analysis, the observational hazard ratio for a doubling in non-fasting triglycerides was 1.57 (1.32-2.68) compared with a causal genetic odds ratio of 1.94 (1.40-1.85) (P for comparison = 0.28). For calculated remnant cholesterol, the corresponding values were 1.67(1.38-2.02) observational and 2.23(1.48-3.35) causal (P for comparison = 0.21). These data are consistent with a causal association between elevated levels of remnant cholesterol in hypertriglyceridaemia and an increased risk of MI. Limitations include that remnants were not measured directly, and that APOA5 genetic variants may influence other lipoprotein parameters.

  5. Liver function assessment using 99mTc-GSA single-photon emission computed tomography (SPECT)/CT fusion imaging in hilar bile duct cancer: A retrospective study.

    PubMed

    Sumiyoshi, Tatsuaki; Shima, Yasuo; Okabayashi, Takehiro; Kozuki, Akihito; Hata, Yasuhiro; Noda, Yoshihiro; Kouno, Michihiko; Miyagawa, Kazuyuki; Tokorodani, Ryotaro; Saisaka, Yuichi; Tokumaru, Teppei; Nakamura, Toshio; Morita, Sojiro

    2016-07-01

    The objective of this study was to determine the utility of Tc-99m-diethylenetriamine-penta-acetic acid-galactosyl human serum albumin ((99m)Tc-GSA) single-photon emission computed tomography (SPECT)/CT fusion imaging for posthepatectomy remnant liver function assessment in hilar bile duct cancer patients. Thirty hilar bile duct cancer patients who underwent major hepatectomy with extrahepatic bile duct resection were retrospectively analyzed. Indocyanine green plasma clearance rate (KICG) value and estimated KICG by (99m)Tc-GSA scintigraphy (KGSA) and volumetric and functional rates of future remnant liver by (99m)Tc-GSA SPECT/CT fusion imaging were used to evaluate preoperative whole liver function and posthepatectomy remnant liver function, respectively. Remnant (rem) KICG (= KICG × volumetric rate) and remKGSA (= KGSA × functional rate) were used to predict future remnant liver function; major hepatectomy was considered unsafe for values <0.05. The correlation of remKICG and remKGSA with posthepatectomy mortality and morbidity was determined. Although remKICG and remKGSA were not significantly different (median value: 0.071 vs 0.075), functional rates of future remnant liver were significantly higher than volumetric rates (median: 0.54 vs 0.46; P < .001). Hepatectomy was considered unsafe in 17% and 0% of patients using remKICG and remKGSA, respectively. Postoperative liver failure and mortality did not occur in the patients for whom hepatectomy was considered unsafe based on remKICG. remKGSA showed a stronger correlation with postoperative prothrombin time activity than remKICG. (99m)Tc-GSA SPECT/CT fusion imaging enables accurate assessment of future remnant liver function and suitability for hepatectomy in hilar bile duct cancer patients. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. The surrounding landscape influences the diversity of leaf-litter ants in riparian cloud forest remnants.

    PubMed

    García-Martínez, Miguel Á; Valenzuela-González, Jorge E; Escobar-Sarria, Federico; López-Barrera, Fabiola; Castaño-Meneses, Gabriela

    2017-01-01

    Riparian vegetation is a distinctive and ecologically important element of landscapes worldwide. However, the relative influence of the surrounding landscape on the conservation of the biodiversity of riparian remnants in human-modified tropical landscapes is poorly understood. We studied the surrounding landscape to evaluate its influence on leaf-litter-ant alpha and beta diversity in riparian remnants in the tropical montane cloud forest region of central Veracruz, Mexico. Sampling was carried out in 12 sites with riparian vegetation during both rainy (2011) and dry (2012) seasons. Ten leaf-litter samples were collected along a 100-m transect per site and processed with Berlese-Tullgren funnels and Winkler sacks. Using remotely-sensed and ground-collected data, we characterized the landscape around each site according to nine land cover types and computed metrics of landscape composition and configuration. We collected a total of 8,684 ant individuals belonging to 53 species, 22 genera, 11 tribes, and 7 subfamilies. Species richness and the diversity of Shannon and Simpson increased significantly in remnants immersed in landscapes with a high percentage of riparian land cover and a low percentage of land covers with areas reforested with Pinus, cattle pastures, and human settlements and infrastructure. The composition of ant assemblages was a function of the percentage of riparian land cover in the landscape. This study found evidence that leaf-litter ants, a highly specialized guild of arthropods, are mainly impacted by landscape composition and the configuration of the focal remnant. Maintaining or improving the surrounding landscape quality of riparian vegetation remnants can stimulate the movement of biodiversity among forest and riparian remnants and foster the provision of ecosystem services by these ecosystems. Effective outcomes may be achieved by considering scientific knowledge during the early stages of riparian policy formulation, in addition to integrating riparian management strategies with broader environmental planning instruments.

  7. The surrounding landscape influences the diversity of leaf-litter ants in riparian cloud forest remnants

    PubMed Central

    Valenzuela-González, Jorge E.; Escobar-Sarria, Federico; López-Barrera, Fabiola; Castaño-Meneses, Gabriela

    2017-01-01

    Riparian vegetation is a distinctive and ecologically important element of landscapes worldwide. However, the relative influence of the surrounding landscape on the conservation of the biodiversity of riparian remnants in human-modified tropical landscapes is poorly understood. We studied the surrounding landscape to evaluate its influence on leaf-litter-ant alpha and beta diversity in riparian remnants in the tropical montane cloud forest region of central Veracruz, Mexico. Sampling was carried out in 12 sites with riparian vegetation during both rainy (2011) and dry (2012) seasons. Ten leaf-litter samples were collected along a 100-m transect per site and processed with Berlese-Tullgren funnels and Winkler sacks. Using remotely-sensed and ground-collected data, we characterized the landscape around each site according to nine land cover types and computed metrics of landscape composition and configuration. We collected a total of 8,684 ant individuals belonging to 53 species, 22 genera, 11 tribes, and 7 subfamilies. Species richness and the diversity of Shannon and Simpson increased significantly in remnants immersed in landscapes with a high percentage of riparian land cover and a low percentage of land covers with areas reforested with Pinus, cattle pastures, and human settlements and infrastructure. The composition of ant assemblages was a function of the percentage of riparian land cover in the landscape. This study found evidence that leaf-litter ants, a highly specialized guild of arthropods, are mainly impacted by landscape composition and the configuration of the focal remnant. Maintaining or improving the surrounding landscape quality of riparian vegetation remnants can stimulate the movement of biodiversity among forest and riparian remnants and foster the provision of ecosystem services by these ecosystems. Effective outcomes may be achieved by considering scientific knowledge during the early stages of riparian policy formulation, in addition to integrating riparian management strategies with broader environmental planning instruments. PMID:28234948

  8. Agricultural Intensification Exacerbates Spillover Effects on Soil Biogeochemistry in Adjacent Forest Remnants

    PubMed Central

    Didham, Raphael K.; Barker, Gary M.; Bartlam, Scott; Deakin, Elizabeth L.; Denmead, Lisa H.; Fisk, Louise M.; Peters, Jennifer M. R.; Tylianakis, Jason M.; Wright, Hannah R.; Schipper, Louis A.

    2015-01-01

    Land-use intensification is a central element in proposed strategies to address global food security. One rationale for accepting the negative consequences of land-use intensification for farmland biodiversity is that it could ‘spare’ further expansion of agriculture into remaining natural habitats. However, in many regions of the world the only natural habitats that can be spared are fragments within landscapes dominated by agriculture. Therefore, land-sparing arguments hinge on land-use intensification having low spillover effects into adjacent protected areas, otherwise net conservation gains will diminish with increasing intensification. We test, for the first time, whether the degree of spillover from farmland into adjacent natural habitats scales in magnitude with increasing land-use intensity. We identified a continuous land-use intensity gradient across pastoral farming systems in New Zealand (based on 13 components of farmer input and soil biogeochemistry variables), and measured cumulative off-site spillover effects of fertilisers and livestock on soil biogeochemistry in 21 adjacent forest remnants. Ten of 11 measured soil properties differed significantly between remnants and intact-forest reference sites, for both fenced and unfenced remnants, at both edge and interior. For seven variables, the magnitude of effects scaled significantly with magnitude of surrounding land-use intensity, through complex interactions with fencing and edge effects. In particular, total C, total N, δ15N, total P and heavy-metal contaminants of phosphate fertilizers (Cd and U) increased significantly within remnants in response to increasing land-use intensity, and these effects were exacerbated in unfenced relative to fenced remnants. This suggests movement of livestock into surrounding natural habitats is a significant component of agricultural spillover, but pervasive changes in soil biogeochemistry still occur through nutrient spillover channels alone, even in fenced remnants set aside for conservation. These results have important implications for the viability of land-sparing as a strategy for balancing landscape-level conservation and production goals in agricultural landscapes. PMID:25575017

  9. Supernova Remnant in 3-D

    NASA Image and Video Library

    2009-01-06

    For the first time, a multiwavelength three-dimensional reconstruction of a supernova remnant has been created. This visualization of Cassiopeia A, or Cas A, the result of an explosion approximately 330 years ago, uses data from several NASA telescopes.

  10. G306.3-0.9: A Newly Discovered Young Galactic Supernova Remnant

    NASA Technical Reports Server (NTRS)

    Reynolds, Mark T.; Loi, Syheh T.; Murphy, Tara; Miller, Jon M.; Maitra, Dipankar; Gueltekin, Kayhan; Gehrels, Neil; Kennea, Jamie A.; Siegel, Michael H.; Gelbord, Jonathan; hide

    2013-01-01

    We present X-ray and radio observations of the new Galactic supernova remnant (SNR) G306.3-0.9, recently discovered by Swift. Chandra imaging reveals a complex morphology, dominated by a bright shock. The X-ray spectrum is broadly consistent with a young SNR in the Sedov phase, implying an age of 2500 yr for a distance of 8 kpc, plausibly identifying this as one of the 20 youngest Galactic SNRs. Australia Telescope Compact Array imaging reveals a prominent ridge of radio emission that correlates with the X-ray emission. We find a flux density of 160 mJy at 1 GHz, which is the lowest radio flux recorded for a Galactic SNR to date. The remnant is also detected at 24µm, indicating the presence of irradiated warm dust. The data reveal no compelling evidence for the presence of a compact stellar remnant.

  11. How high energy fluxes may affect Rayleigh–Taylor instability growth in young supernova remnants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kuranz, Carolyn C.; Park, Hye -Sook; Huntington, Channing M.

    Here, energy-transport effects can alter the structure that develops as a supernova evolves into a supernova remnant. The Rayleigh–Taylor instability is thought to produce structure at the interface between the stellar ejecta and the circumstellar matter, based on simple models and hydrodynamic simulations. Here we report experimental results from the National Ignition Facility to explore how large energy fluxes, which are present in supernovae, affect this structure. We observed a reduction in Rayleigh–Taylor growth. In analyzing the comparison with supernova SN1993J, a Type II supernova, we found that the energy fluxes produced by heat conduction appear to be larger thanmore » the radiative energy fluxes, and large enough to have dramatic consequences. No reported astrophysical simulations have included radiation and heat conduction self-consistently in modeling supernova remnants and these dynamics should be noted in the understanding of young supernova remnants.« less

  12. Fermi Large Area Telescope Detection of Supernova Remnant RCW 86

    NASA Astrophysics Data System (ADS)

    Yuan, Qiang; Huang, Xiaoyuan; Liu, Siming; Zhang, Bing

    2014-04-01

    Using 5.4 yr Fermi Large Area Telescope data, we report the detection of GeV γ-ray emission from the shell-type supernova remnant RCW 86 (G315.4-2.3) with a significance of ~5.1σ. The data slightly favors an extended emission of this supernova remnant. The spectral index of RCW 86 is found to be very hard, Γ ~ 1.4, in the 0.4-300 GeV range. A one-zone leptonic model can well fit the multi-wavelength data from radio to very high energy γ-rays. The very hard GeV γ-ray spectrum and the inferred low gas density seem to disfavor a hadronic origin for the γ-rays. The γ-ray behavior of RCW 86 is very similar to several other TeV shell-type supernova remnants, e.g., RX J1713.7-3946, RX J0852.0-4622, SN 1006, and HESS J1731-347.

  13. Probing the Reverse Shock in an Oxygen-Rich Supernova Remnant

    NASA Technical Reports Server (NTRS)

    Sonneborn, George (Technical Monitor); Gaetz, Terrance J.

    2003-01-01

    The aim of this proposal was to examine the O VI emission at three positions around the X-ray bright ring of the remnant in order to investigate the relation between the O VI emission, the X-ray O VII and O VIII emission, and the optical [O III] emission, and how these vary around the rim of the remnant. So far, only one Far Ultraviolet Spectroscopic Explorer (FUSE) pointing at the remnant has been performed, together with the background pointing needed to subtract the diffuse scattered light from nearby O stars. The data were recalibrated using the CalFUSE calibration pipeline, but the emission is faint enough that hand processing will be needed for this pointing to optimize the extraction. Rereduction of the data is underway. A postdoctoral fellow has also been hired, and in part she will assist with the analysis.

  14. Study of the photon remnant in resolved photoproduction at HERA

    NASA Astrophysics Data System (ADS)

    Derrick, M.; Krakauer, D.; Magill, S.; Mikunas, D.; Musgrave, B.; Repond, J.; Stanek, R.; Talaga, R. L.; Zhang, H.; Ayad, R.; Bari, G.; Basile, M.; Bellagamba, L.; Boscherini, D.; Bruni, A.; Bruni, G.; Bruni, P.; Cara Romeo, G.; Castellini, G.; Chiarini, M.; Cifarelli, L.; Cindolo, F.; Contin, A.; Corradi, M.; Gialas, I.; Giusti, P.; Iacobucci, G.; Laurenti, G.; Levi, G.; Margotti, A.; Massam, T.; Nania, R.; Nemoz, C.; Palmonari, F.; Polini, A.; Sartorelli, G.; Timellini, R.; Zamora Garcia, Y.; Zichichi, A.; Bargende, A.; Crittenden, J.; Desch, K.; Diekmann, B.; Doeker, T.; Eckert, M.; Feld, L.; Frey, A.; Geerts, M.; Geitz, G.; Grothe, M.; Haas, T.; Hartmann, H.; Heinloth, K.; Hilger, E.; Jakob, H.-P.; Katz, U. F.; Mari, S. M.; Mass, A.; Mengel, S.; Mollen, J.; Paul, E.; Rembser, Ch; Schramm, D.; Stamm, J.; Wedemeyer, R.; Campbell-Robson, S.; Cassidy, A.; Dyce, N.; Foster, B.; George, S.; Gilmore, R.; Heath, G. P.; Heath, H. F.; Llewellyn, T. J.; Morgado, C. J. S.; Norman, D. J. P.; O'Mara, J. A.; Tapper, R. J.; Wilson, S. S.; Yoshida, R.; Rau, R. R.; Arneodo, M.; Iannotti, L.; Schioppa, M.; Susinno, G.; Bernstein, A.; Caldwell, A.; Cartiglia, N.; Parsons, J. A.; Ritz, S.; Sciulli, F.; Straub, P. B.; Wai, L.; Yang, S.; Zhu, Q.; Borzemski, P.; Chwastowski, J.; Eskreys, A.; Piotrzkowski, K.; Zachara, M.; Zawiejski, L.; Adamczyk, L.; Bednarek, B.; Jeleń, K.; Kisielewska, D.; Kowalski, T.; Rulikowska-Zarȩbska, E.; Suszycki, L.; Zajaç, J.; Kotański, A.; Przybycień, M.; Bauerdick, L. A. T.; Behrens, U.; Beier, H.; Bienlein, J. K.; Coldewey, C.; Deppe, O.; Desler, K.; Drews, G.; Flasiński, M.; Gilkinson, D. J.; Glasman, C.; Göttlicher, P.; Große-Knetter, J.; Gutjahr, B.; Hain, W.; Hasell, D.; Heßling, H.; Iga, Y.; Joos, P.; Kasemann, M.; Klanner, R.; Koch, W.; Köpke, L.; Kötz, U.; Kowalski, H.; Labs, J.; Ladage, A.; Löhr, B.; Löwe, M.; Lüke, D.; Mainusch, J.; Mańczak, O.; Monteiro, T.; Ng, J. S. T.; Nickel, S.; Notz, D.; Ohrenberg, K.; Roco, M.; Rohde, M.; Roldán, J.; Schneekloth, U.; Schulz, W.; Selonke, F.; Stiliaris, E.; Surrow, B.; Voß, T.; Westphal, D.; Wolf, G.; Youngman, C.; Zhou, J. F.; Grabosch, H. J.; Kharchilava, A.; Leich, A.; Mattingly, M. C. K.; Meyer, A.; Schlenstedt, S.; Wulff, N.; Barbagli, G.; Pelfer, P.; Anzivino, G.; Maccarrone, G.; De Pasquale, S.; Votano, L.; Bamberger, A.; Eisenhardt, S.; Freidhof, A.; Söldner-Rembold, S.; Schroeder, J.; Trefzger, T.; Brook, N. H.; Bussey, P. J.; Doyle, A. T.; Fleck, J. I.; Saxon, D. H.; Utley, M. L.; Wilson, A. S.; Dannemann, A.; Holm, U.; Horstmann, D.; Neumann, T.; Sinkus, R.; Wick, K.; Badura, E.; Burow, B. D.; Hagge, L.; Lohrmann, E.; Milewski, J.; Nakahata, M.; Pavel, N.; Poelz, G.; Schott, W.; Zetsche, F.; Bacon, T. C.; Butterworth, I.; Gallo, E.; Harris, V. L.; Hung, B. Y. H.; Long, K. R.; Miller, D. B.; Morawitz, P. P. O.; Prinias, A.; Sedgbeer, J. K.; Whitfield, A. F.; Mallik, U.; McCliment, E.; Wang, M. Z.; Wang, S. M.; Wu, J. T.; Zhang, Y.; Cloth, P.; Filges, D.; An, S. H.; Hong, S. M.; Nam, S. W.; Park, S. K.; Suh, M. H.; Yon, S. H.; Imlay, R.; Kartik, S.; Kim, H.-J.; McNeil, R. R.; Metcalf, W.; Nadendla, V. K.; Barreiro, F.; Cases, G.; Fernandez, J. P.; Graciani, R.; Hernández, J. M.; Hervás, L.; Labarga, L.; Martinez, M.; del Peso, J.; Puga, J.; Terron, J.; de Trocóniz, J. F.; Smith, G. R.; Corriveau, F.; Hanna, D. S.; Hartmann, J.; Hung, L. W.; Lim, J. N.; Matthews, C. G.; Patel, P. M.; Sinclair, L. E.; Stairs, D. G.; St. Laurent, M.; Ullmann, R.; Zacek, G.; Bashkirov, V.; Dolgoshein, B. A.; Stifutkin, A.; Bashindzhagyan, G. L.; Ermolov, P. F.; Gladilin, L. K.; Golubkov, Y. A.; Kobrin, V. D.; Kuzmin, V. A.; Proskuryakov, A. S.; Savin, A. A.; Shcheglova, L. M.; Solomin, A. N.; Zotov, N. P.; Botje, M.; Chlebana, F.; Dake, A.; Engelen, J.; de Kamps, M.; Kooijman, P.; Kruse, A.; Tiecke, H.; Verkerke, W.; Vreeswijk, M.; Wiggers, L.; de Wolf, E.; van Woudenberg, R.; Acosta, D.; Bylsma, B.; Durkin, L. S.; Honscheid, K.; Li, C.; Ling, T. Y.; McLean, K. W.; Murray, W. N.; Park, I. H.; Romanowski, T. A.; Seidlein, R.; Bailey, D. S.; Byrne, A.; Cashmore, R. J.; Cooper-Sarkar, A. M.; Devenish, R. C. E.; Harnew, N.; Lancaster, M.; Lindemann, L.; McFall, J. D.; Nath, C.; Noyes, V. A.; Quadt, A.; Tickner, J. R.; Uijterwaal, H.; Walczak, R.; Waters, D. S.; Wilson, F. F.; Yip, T.; Abbiendi, G.; Bertolin, A.; Brugnera, R.; Carlin, R.; Dal Corso, F.; De Giorgi, M.; Dosselli, U.; Limentani, S.; Morandin, M.; Posocco, M.; Stanco, L.; Stroili, R.; Voci, C.; Bulmahn, J.; Butterworth, J. M.; Feild, R. G.; Oh, B. Y.; Whitmore, J. J.; D'Agostini, G.; Marini, G.; Nigro, A.; Tassi, E.; Hart, J. C.; McCubbin, N. A.; Prytz, K.; Shah, T. P.; Short, T. L.; Barberis, E.; Dubbs, T.; Heusch, C.; Van Hook, M.; Hubbard, B.; Lockman, W.; Rahn, J. T.; Sadrozinski, H. F.-W.; Seiden, A.; Biltzinger, J.; Seifert, R. J.; Schwarzer, O.; Walenta, A. H.; Zech, G.; Abramowicz, H.; Briskin, G.; Dagan, S.; Levy, A.; Hasegawa, T.; Hazumi, M.; Ishii, T.; Kuze, M.; Mine, S.; Nagasawa, Y.; Nakao, M.; Suzuki, I.; Tokushuku, K.; Yamada, S.; Yamazaki, Y.; Chiba, M.; Hamatsu, R.; Hirose, T.; Homma, K.; Kitamura, S.; Nakamitsu, Y.; Yamauchi, K.; Cirio, R.; Costa, M.; Ferrero, M. I.; Lamberti, L.; Maselli, S.; Peroni, C.; Sacchi, R.; Solano, A.; Staiano, A.; Dardo, M.; Bailey, D. C.; Bandyopadhyay, D.; Benard, F.; Brkic, M.; Crombie, M. B.; Gingrich, D. M.; Hartner, G. F.; Joo, K. K.; Levman, G. M.; Martin, J. F.; Orr, R. S.; Sampson, C. R.; Teuscher, R. J.; Catterall, C. D.; Jones, T. W.; Kaziewicz, P. B.; Lane, J. B.; Saunders, R. L.; Shulman, J.; Blankenship, K.; Lu, B.; Mo, L. W.; Bogusz, W.; Charchuła, K.; Ciborowski, J.; Gajewski, J.; Grzelak, G.; Kasprzak, M.; Krzyżanowski, M.; Muchorowski, K.; Nowak, R. J.; Pawlak, J. M.; Tymieniecka, T.; Wróblewski, A. K.; Zakrzewski, J. A.; Żarnecki, A. F.; Adamus, M.; Eisenberg, Y.; Karshon, U.; Revel, D.; Zer-Zion, D.; Ali, I.; Badgett, W. F.; Behrens, B.; Dasu, S.; Fordham, C.; Foudas, C.; Goussiou, A.; Loveless, R. J.; Reeder, D. D.; Silverstein, S.; Smith, W. H.; Vaiciulis, A.; Wodarczyk, M.; Tsurugai, T.; Bhadra, S.; Cardy, M. L.; Fagerstroem, C.-P.; Frisken, W. R.; Furutani, K. M.; Khakzad, M.; Schmidke, W. B.; ZEUS Collaboration

    1995-02-01

    Photoproduction at HERA is studied in ep collisions, with the ZEUS detector, for γp centre-of-mass energies ranging from 130-270 GeV. A sample of events with two high- pT jets ( pT > 6 GeV, η < 1.6) and a third cluster in the approximate direction of the electron beam is isolated using a clustering algorithm. These events are mostly due to resolved photoproduction. The third cluster is identified as the photon remnant. Its properties, such as the transverse and longitudinal energy flows around the axis of the cluster, are consistent with those commonly attributed to jets, and in particular with those found for the two jets in these events. The mean value of the photon remnant pT with respect to the beam axis is measured to be 2.1 ± 0.2 GeV, which demonstrates substantial mean transverse momenta for the photon remnant.

  15. Identification of the membrane remnants of transferrin receptor with domain-specific antibodies.

    PubMed

    Baynes, R D; Shih, Y J; Hudson, B G; Cook, J D

    1994-03-01

    Tissue culture studies with K562 and HL60 cells have demonstrated the production of a soluble form of transferrin receptor identical to that identified in human serum. The present study was undertaken to search for membrane remnants of the truncated receptor with peptide antibodies specific for the extracellular and cytoplasmic domain of transferrin receptor. In cell membranes, a 105K remnant was identified that is consistent with truncation of one extracellular domain monomer of the transferrin receptor. In the exosomal fraction of the culture supernatant, a smaller 20K remnant consistent with truncation of both extracellular domains was also demonstrated. These findings provide evidence that soluble receptor is the product of proteolytic cleavage of intact membrane-bound transferrin receptor. Prior studies showing that the concentration of the extracellular domain in exosomes remained stable during incubation in culture supernatant suggest that this cleavage possibly occurs intracellularly.

  16. Gravitational waves from remnant massive neutron stars of binary neutron star merger: Viscous hydrodynamics effects

    NASA Astrophysics Data System (ADS)

    Shibata, Masaru; Kiuchi, Kenta

    2017-06-01

    Employing a simplified version of the Israel-Stewart formalism of general-relativistic shear-viscous hydrodynamics, we explore the evolution of a remnant massive neutron star of binary neutron star merger and pay special attention to the resulting gravitational waveforms. We find that for the plausible values of the so-called viscous alpha parameter of the order 10-2 the degree of the differential rotation in the remnant massive neutron star is significantly reduced in the viscous time scale, ≲5 ms . Associated with this, the degree of nonaxisymmetric deformation is also reduced quickly, and as a consequence, the amplitude of quasiperiodic gravitational waves emitted also decays in the viscous time scale. Our results indicate that for modeling the evolution of the merger remnants of binary neutron stars we would have to take into account magnetohydrodynamics effects, which in nature could provide the viscous effects.

  17. How high energy fluxes may affect Rayleigh–Taylor instability growth in young supernova remnants

    DOE PAGES

    Kuranz, Carolyn C.; Park, Hye -Sook; Huntington, Channing M.; ...

    2018-04-19

    Here, energy-transport effects can alter the structure that develops as a supernova evolves into a supernova remnant. The Rayleigh–Taylor instability is thought to produce structure at the interface between the stellar ejecta and the circumstellar matter, based on simple models and hydrodynamic simulations. Here we report experimental results from the National Ignition Facility to explore how large energy fluxes, which are present in supernovae, affect this structure. We observed a reduction in Rayleigh–Taylor growth. In analyzing the comparison with supernova SN1993J, a Type II supernova, we found that the energy fluxes produced by heat conduction appear to be larger thanmore » the radiative energy fluxes, and large enough to have dramatic consequences. No reported astrophysical simulations have included radiation and heat conduction self-consistently in modeling supernova remnants and these dynamics should be noted in the understanding of young supernova remnants.« less

  18. Parameterizing the Supernova Engine and Its Effect on Remnants and Basic Yields

    NASA Astrophysics Data System (ADS)

    Fryer, Chris L.; Andrews, Sydney; Even, Wesley; Heger, Alex; Safi-Harb, Samar

    2018-03-01

    Core-collapse supernova science is now entering an era in which engine models are beginning to make both qualitative and, in some cases, quantitative predictions. Although the evidence in support of the convective engine for core-collapse supernova continues to grow, it is difficult to place quantitative constraints on this engine. Some studies have made specific predictions for the remnant distribution from the convective engine, but the results differ between different groups. Here we use a broad parameterization for the supernova engine to understand the differences between distinct studies. With this broader set of models, we place error bars on the remnant mass and basic yields from the uncertainties in the explosive engine. We find that, even with only three progenitors and a narrow range of explosion energies, we can produce a wide range of remnant masses and nucleosynthetic yields.

  19. A Central Source in the Supernova Remnant Kes 79

    NASA Astrophysics Data System (ADS)

    Seward, F.; Slane, P.; Smith, R.; Sun, M.

    2002-04-01

    Kes 79 (G33.6+0.1) was observed 31 July 2001 for 30 ks with the Chandra ACIS-I instrument. This remnant, in the constellation Aquila, lies in the galactic plane at a distance of ~10 kpc. The 11^' angular diameter implies an age of a few thousand years. The morphology shows faint outer and bright inner shells. The Chandra image reveals, for the first time, a point-like source at the center of the remnant. This source has a black body spectrum with kT = 0.5 keV. No regular pulsations were found at periods greater than 6.4 s (the ACIS integration time is 3.2 s). No surrounding synchrotron emission wass detected. The X-ray luminosity is 7 × 10^33 erg/s, about 1% the luminosity of the entire remnant. The source may be similar to the one at the center of Cas A.

  20. Misconceptions Highlighted among Medical Students in the Annual International Intermedical School Physiology Quiz

    ERIC Educational Resources Information Center

    Cheng, Hwee-Ming; Durairajanayagam, Damayanthi

    2012-01-01

    The annual Intermedical School Physiology Quiz (IMSPQ), initiated in 2003, is now an event that attracts a unique, large gathering of selected medical students from medical schools across the globe. The 8th IMSPQ, in 2010, hosted by the Department of Physiology, University of Malaya, in Kuala Lumpur, Malaysia, had 200 students representing 41…

  1. Hot spot abundance, ridge subduction and the evolution of greenstone belts

    NASA Technical Reports Server (NTRS)

    Abbott, D.; Hoffman, S.

    1986-01-01

    A number of plate tectonic hypotheses have been proposed to explain the origin of Archaean and Phanerozoic greenstone/ophiolite terranes. In these models, ophiolites or greenstone belts represent the remnants of one or more of the following: island arcs, rifted continental margins, oceanic crustal sections, and hot spot volcanic products. If plate tectonics has been active since the creation of the Earth, it is logical to suppose that the same types of tectonic processes which form present day ophiolites also formed Archaean greenstone belts. However, the relative importance of the various tectonic processes may well have been different and are discussed.

  2. Deep Radio Imaging with MERLIN of the Supernova Remnants in M82

    NASA Astrophysics Data System (ADS)

    Muxlow, T. W. B.; Pedlar, A.; Riley, J. D.; McDonald, A. R.; Beswick, R. J.; Wills, K. A.

    An 8 day MERLIN deep integration at 5GHz of the central region of the starburst galaxy M82 has been used to investigate the radio structure of a number of supernova remnants in unprecedented detail revealing new shells and partial shell structures for the first time. In addition, by comparing the new deep 2002 image with an astrometrically aligned image from 36 hours of data taken in 1992, it has been possible to directly measure the expansion velocities of 4 of the most compact remnants in M82. For the two most compact remnants, 41.95+575 and 43.31+592, expansion velocities of 2800 ± 300 km s-1 and 8750 ± 400 km s-1 have been derived. These confirm and refine the measured expansion velocities which have been derived from VLBI multi-epoch studies. For remnants 43.18+583 and 44.01+596, expansion velocities of 10500 ± 750 km s -1 and 2400 ± 250 km s-1 have been measured for the first time. In addition, the peak of the radio emission for SNR 45.17+612 has moved between the two epochs implying velocities around 7500km s-1. The relatively compact remnants in M82 are thus found to be expanding over a wide range of velocities which appear unrelated to their size. The new 2002 map is the most sensitive high-resolution image yet made of M82, achieving an rms noise level of 17µJy beam-1. This establishes a first epoch for subsequent deep studies of expansion velocities for many SNR within M82.

  3. Does the tibial remnant of the anterior cruciate ligament promote ligamentization?

    PubMed

    Lee, Byung Ill; Kim, Byoung Min; Kho, Duk Hwan; Kwon, Sai Won; Kim, Hyeung June; Hwang, Hyun Ryong

    2016-12-01

    The purpose of this study was to clarify the difference in ligamentization between the remnant-preserving (RP) and remnant-sacrificing (RS) techniques in anterior cruciate ligament (ACL) reconstruction using magnetic resonance imaging (MRI). A retrospective comparative study was carried out on 98 patients undergoing ACL reconstruction using either an RP (n=56) or RS (n=42) technique. MRI was performed at one of four time points postoperatively, and the signal intensity of the ACL graft was analyzed using the signal to noise quotient (SNQ) ratio and inter-bundle high signal intensity, along with an analysis of the survival rate of remnant tissue. The mean SNQ ratio of grafted tendons in the RP group was significantly higher than that seen in the RS group in the proximal and middle regions two to four months after surgery (P<0.05) and was significantly lower than that seen in the RS group in all regions at 12 -18months (P<0.05). The inter-bundle high signal intensity was observed more frequently in the RP group (73.7%) at two to four months. Tibial remnants were observed on postoperative MRI regardless of when MRI was conducted. The ACL graft of the RP group showed higher signal intensity in the early stage and lower signal intensity in the late stage compared to that of the RS group. The ligamentization of grafts in the RP group proceeded more quickly. Preserving the remnant in ACL reconstruction appears to have a positive effect on ligamentization. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. A comparative study of qualitative and quantitative methods for the assessment of adhesive remnant after bracket debonding.

    PubMed

    Cehreli, S Burcak; Polat-Ozsoy, Omur; Sar, Cagla; Cubukcu, H Evren; Cehreli, Zafer C

    2012-04-01

    The amount of the residual adhesive after bracket debonding is frequently assessed in a qualitative manner, utilizing the adhesive remnant index (ARI). This study aimed to investigate whether quantitative assessment of the adhesive remnant yields more precise results compared to qualitative methods utilizing the 4- and 5-point ARI scales. Twenty debonded brackets were selected. Evaluation and scoring of the adhesive remnant on bracket bases were made consecutively using: 1. qualitative assessment (visual scoring) and 2. quantitative measurement (image analysis) on digital photographs. Image analysis was made on scanning electron micrographs (SEM) and high-precision elemental maps of the adhesive remnant as determined by energy dispersed X-ray spectrometry. Evaluations were made in accordance with the original 4-point and the modified 5-point ARI scales. Intra-class correlation coefficients (ICCs) were calculated, and the data were evaluated using Friedman test followed by Wilcoxon signed ranks test with Bonferroni correction. ICC statistics indicated high levels of agreement for qualitative visual scoring among examiners. The 4-point ARI scale was compliant with the SEM assessments but indicated significantly less adhesive remnant compared to the results of quantitative elemental mapping. When the 5-point scale was used, both quantitative techniques yielded similar results with those obtained qualitatively. These results indicate that qualitative visual scoring using the ARI is capable of generating similar results with those assessed by quantitative image analysis techniques. In particular, visual scoring with the 5-point ARI scale can yield similar results with both the SEM analysis and elemental mapping.

  5. Housing Shortages in Urban Regions: Aggressive Interactions at Tree Hollows in Forest Remnants

    PubMed Central

    Davis, Adrian; Major, Richard E.; Taylor, Charlotte E.

    2013-01-01

    Urbanisation typically results in a reduction of hollow-bearing trees and an increase in the density of particularly species, potentially resulting in an increased level of competition as cavity-nesting species compete for a limited resource. To improve understanding of hollow usage between urban cavity-nesting species in Australia, particularly parrots, we investigated how the hollow-using assemblage, visitation rate, diversity and number of interactions varied between hollows within urban remnant forest and continuous forest. Motion-activated video cameras were installed, via roped access to the canopy, and hollow usage was monitored at 61 hollows over a two-year period. Tree hollows within urban remnants had a significantly different assemblage of visitors to those in continuous forest as well as a higher rate of visitation than hollows within continuous forest, with the rainbow lorikeet making significantly more visitations than any other taxa. Hollows within urban remnants were characterised by significantly higher usage rates and significantly more aggressive interactions than hollows within continuous forest, with parrots responsible for almost all interactions. Within urban remnants, high rates of hollow visitation and both interspecific and intraspecific interactions observed at tree hollows suggest the number of available optimal hollows may be limiting. Understanding the usage of urban remnant hollows by wildlife, as well as the role of parrots as a potential flagship for the conservation of tree-hollows, is vital to prevent a decrease in the diversity of urban fauna, particularly as other less competitive species risk being outcompeted by abundant native species. PMID:23555657

  6. Ontology of physics for biology: representing physical dependencies as a basis for biological processes

    PubMed Central

    2013-01-01

    Background In prior work, we presented the Ontology of Physics for Biology (OPB) as a computational ontology for use in the annotation and representations of biophysical knowledge encoded in repositories of physics-based biosimulation models. We introduced OPB:Physical entity and OPB:Physical property classes that extend available spatiotemporal representations of physical entities and processes to explicitly represent the thermodynamics and dynamics of physiological processes. Our utilitarian, long-term aim is to develop computational tools for creating and querying formalized physiological knowledge for use by multiscale “physiome” projects such as the EU’s Virtual Physiological Human (VPH) and NIH’s Virtual Physiological Rat (VPR). Results Here we describe the OPB:Physical dependency taxonomy of classes that represent of the laws of classical physics that are the “rules” by which physical properties of physical entities change during occurrences of physical processes. For example, the fluid analog of Ohm’s law (as for electric currents) is used to describe how a blood flow rate depends on a blood pressure gradient. Hooke’s law (as in elastic deformations of springs) is used to describe how an increase in vascular volume increases blood pressure. We classify such dependencies according to the flow, transformation, and storage of thermodynamic energy that occurs during processes governed by the dependencies. Conclusions We have developed the OPB and annotation methods to represent the meaning—the biophysical semantics—of the mathematical statements of physiological analysis and the biophysical content of models and datasets. Here we describe and discuss our approach to an ontological representation of physical laws (as dependencies) and properties as encoded for the mathematical analysis of biophysical processes. PMID:24295137

  7. FEATURE C. MACHINE GUN POSITION WITH REMNANT OF MOUNT, VIEW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FEATURE C. MACHINE GUN POSITION WITH REMNANT OF MOUNT, VIEW FACING SOUTH-SOUTHEAST. - Naval Air Station Barbers Point, Battery-Machine Gun Positions, South of Point Cruz Road & west of Coral Sea Road, Ewa, Honolulu County, HI

  8. [Rare umbilical anomalies].

    PubMed

    Kysucan, J; Malý, T; Neoral, C

    2010-12-01

    Umbilicus is a scar, which is the place of the previous merger of the fetus with the umbilical cord. After birth, it has no known function, however, unless the umbilical annulus is completely closed, umbilical hernia may occur. Umbilical scar is also an area where may occur a number of anomalies that may be present alone or together with umbilical hernia. Failure of involution leads to persistence of omphalomesenteric duct and urachal remnants. These embryonic remnants may cause more or less significant clinical problems, or may be completely asymptomatic and may be diagnosed at random. The authors present their own group of patients who were diagnosed and dealt with the defect omphalomesenteric duct or urachus. In past 7 years we observed 35 children with these abnormalities. A large group of patients represents incidental findings during elective surgery for umbilical hernia. Another large group are patients with symptomatic or asymptomatic Meckel's diverticulum. The anatomical observations, clinical manifestations, complications and treatment of these anomalies are mentioned. A total of 35 children were found with these birth defects. In 23 cases we observed omphalomesenteric duct disorders and 12 urachal remnants were reported. Of these, 12 abnormalities were found incidentally during elative procedure for umbilical hernia. Asymptomatic or symptomatic Meckel's diverticulum appeared in 16 cases. Surgical treatment included resection or exstirpation, if urachal anomaly was accompanied then partial resection of the bladder vertex was added. Postoperative complications emerged in 4 cases, three times it was ileus from adhesions 6 months after surgery, once postoperative cystitis appeared and was treated conservatively. Birth abnormalities of the umbilicus are relatively rare diseases that may occur in the pediatric population. Omfalomesenteric duct and urachal anomalies constitute a major group of these congenital disorders and are often associated with umbilical hernia. They can be diagnosed soon after birth or later in life. Surgical treatment involves excision or radical exstirpation to prevent early or late complications (urachal carcinoma in adulthood).

  9. The imprint of Gould's belt on the local cosmic ray electron spectrum

    NASA Astrophysics Data System (ADS)

    Pohl, M.; Perrot, C.; Grenier, I.

    2001-08-01

    In a recent paper Pohl and Esposito (1998) demonstrated that if the sources of cosmic-rays are discrete, as are Supernova Remnants (SNR), then the spectra of cosmic-ray electrons largely vary with location and time and the locally measured electron spectrum may not be representative of the electron spectra elsewhere in the Galaxy, which could be substantially harder than the local one. They have shown that the observed excess of γ-ray emission above 1 GeV can in fact be partially explained as a correspondingly hard inverse Compton component, provided the bulk of cosmic-ray electrons is produced in SNR. As part of a program to model the Galactic γ-ray foreground we have continued the earlier studies by investigating the impact of the star forming region Gould's Belt on the local electron spectrum. If the electron sources in Gould's Belt were continous, the local electron spectrum would be slightly hardened. If the electron sources are discrete, which is the more probable case, the variation in the local electron spectrum found by Pohl & Esposito persists. 1 The local cosmic-ray electron spectrum The recent detections of non-thermal X-ray synchrotron radiation from the supernova remnants SN1006 (Koyama et al., 1995), RX J1713.7-3946 (Koyama et al., 1997), IC443 (Keohane et al., 1997; Slane et al., 1999), Cas A (Allen et al., 1997), and RCW86 (Borkowski et al., 2001) and the subsequent detections of SN1006 (Tanimori et al., 1998), RX J1713.7-3946 (Muraishi et al., 2000), and Cas A (Aharonian et al., 2001) at TeV energies support the hypothesis that at least Galactic cosmic-ray electrons are accelerated predominantly in SNR. The Galactic distribution and spectrum of cosmic-ray electrons are intimately linked to the distribution and nature of their sources. Supernovae and hence their remnants are tran-

  10. Contrasting Convective Flux Gradients in the U.S. Corn Belt as a Result of Vegetation Land Cover Type

    NASA Astrophysics Data System (ADS)

    Hiestand, M.

    2017-12-01

    Phenological differences between extensive croplands and remnant forests in the U.S. Corn Belt have been suggested as enhancing spatial gradients of latent and sensible heat fluxes that contribute to the distribution and amounts of convective rainfall on mesoscales. However, the exact magnitude of the intra-seasonal variability in convective fluxes between these two land-cover types has yet to be quantified. Previous work suggesting that non-classical mesoscale circulations operate within the Corn Belt has not involved direct flux observations obtained using the eddy flux covariance technique. This study compares five day running means of daily heat fluxes between two Ameriflux towers (US-Bo1 in Illinois and US-MMS in Indiana) representing rain-fed cropland and remnant forest, respectively for the growing seasons of 1999-2008. Latent heat values normalized to the net radiation show higher rates of evapotranspiration at the forested site than over the cropland during the start of the growing season. However, toward the end of the growing season, latent heat fluxes from the forest decrease and the cropland becomes the dominate source of evapotranspiration. Conversely, croplands dominate sensible heat fluxes at the start of the growing season whereas the remnant forests are associated with strong sensible heat fluxes in late summer. These intra-seasonal spatial differences of latent and sensible heat fluxes across the Corn Belt imply differences in moisture pooling that are suggested as enhancing atmospheric convection during favorable synoptic conditions, especially near the boundaries of these two land cover types. Understanding the physical mechanisms by which the spatial distribution of vegetated land cover can generate contrasting latent and sensible heat fluxes will lay the groundwork for improving mesoscale precipitation forecasts in the Corn Belt, and determining the possible impacts of ongoing land-cover and climate changes there.

  11. ON THE EXPANSION RATE, AGE, AND DISTANCE OF THE SUPERNOVA REMNANT G266.2–1.2 (Vela Jr.)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Allen, G. E.; Chow, K.; DeLaney, T.

    An analysis of Chandra ACIS data for two relatively bright and narrow portions of the northwestern rim of G266.2–1.2 (a.k.a. RX J0852.0-4622 or Vela Jr.) reveal evidence of a radial displacement of 2.40 ± 0.56 arcsec between 2003 and 2008. The corresponding expansion rate (0.42 ± 0.10 arcsec yr{sup –1} or 13.6% ± 4.2% kyr{sup –1}) is about half the rate reported for an analysis of XMM-Newton data from a similar, but not identical, portion of the rim over a similar, but not identical, time interval (0.84 ± 0.23 arcsec yr{sup –1}). If the Chandra rate is representative of the remnant as amore » whole, then the results of a hydrodynamic analysis suggest that G266.2–1.2 is between 2.4 and 5.1 kyr old if it is expanding into a uniform ambient medium (whether or not it was produced by a Type Ia or Type II event). If the remnant is expanding into the material shed by a steady stellar wind, then the age could be as much as 50% higher. The Chandra expansion rate and a requirement that the shock speed be greater than or equal to 1000 km s{sup –1} yields a lower limit on the distance of 0.5 kpc. An analysis of previously published distance estimates and constraints suggests G266.2–1.2 is no further than 1.0 kpc. This range of distances is consistent with the distance to the nearer of two groups of material in the Vela Molecular Ridge (0.7 ± 0.2 kpc) and to the Vel OB1 association (0.8 kpc)« less

  12. Gamma-Ray Observations of Tycho’s Supernova Remnant with VERITAS and Fermi

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Archambault, S.; Bourbeau, E.; Feng, Q.

    2017-02-10

    High-energy gamma-ray emission from supernova remnants (SNRs) has provided a unique perspective for studies of Galactic cosmic-ray acceleration. Tycho’s SNR is a particularly good target because it is a young, type Ia SNR that has been well-studied over a wide range of energies and located in a relatively clean environment. Since the detection of gamma-ray emission from Tycho’s SNR by VERITAS and Fermi -LAT, there have been several theoretical models proposed to explain its broadband emission and high-energy morphology. We report on an update to the gamma-ray measurements of Tycho’s SNR with 147 hr of VERITAS and 84 months ofmore » Fermi -LAT observations, which represent about a factor of two increase in exposure over previously published data. About half of the VERITAS data benefited from a camera upgrade, which has made it possible to extend the TeV measurements toward lower energies. The TeV spectral index measured by VERITAS is consistent with previous results, but the expanded energy range softens a straight power-law fit. At energies higher than 400 GeV, the power-law index is 2.92 ± 0.42{sub stat} ± 0.20{sub sys}. It is also softer than the spectral index in the GeV energy range, 2.14 ± 0.09{sub stat} ± 0.02{sub sys}, measured in this study using Fermi -LAT data. The centroid position of the gamma-ray emission is coincident with the center of the remnant, as well as with the centroid measurement of Fermi -LAT above 1 GeV. The results are consistent with an SNR shell origin of the emission, as many models assume. The updated spectrum points to a lower maximum particle energy than has been suggested previously.« less

  13. The Cygnus Loop: An Older Supernova Remnant.

    ERIC Educational Resources Information Center

    Straka, William

    1987-01-01

    Describes the Cygnus Loop, one of brightest and most easily studied of the older "remnant nebulae" of supernova outbursts. Discusses some of the historical events surrounding the discovery and measurement of the Cygnus Loop and makes some projections on its future. (TW)

  14. High energy neutrinos from gamma-ray bursts with precursor supernovae.

    PubMed

    Razzaque, Soebur; Mészáros, Peter; Waxman, Eli

    2003-06-20

    The high energy neutrino signature from proton-proton and photo-meson interactions in a supernova remnant shell ejected prior to a gamma-ray burst provides a test for the precursor supernova, or supranova, model of gamma-ray bursts. Protons in the supernova remnant shell and photons entrapped from a supernova explosion or a pulsar wind from a fast-rotating neutron star remnant provide ample targets for protons escaping the internal shocks of the gamma-ray burst to interact and produce high energy neutrinos. We calculate the expected neutrino fluxes, which can be detected by current and future experiments.

  15. Case report of bilateral cervical chondrocutaneous branchial remnants.

    PubMed

    Braun, Hannes; Hofmann, Thiemo; Wolfgruber, Herwig; Anderhuber, Wolfgang; Beham, Alfred; Stammberger, Heinz

    2003-01-01

    Cervical chondrocutaneous branchial remnants are rare and not well known lesions. Histologically the lesion per definition presents as a Choristoma. Choristoma is the pathohistological term for a developmental tumor-like anomaly consisting of tissues foreign to the site at which it is located. Treatment is complete surgical removal as promptly as possible in order to get an exact histopathological diagnosis. A case of a 4-month-old boy with cervical chondrocutaneous branchial remnants anterior to the sternocleidomastoid muscles on both sides is presented. According to literature search this appears to be the second case published on such a bilateral lesion.

  16. X-Ray Ejecta Kinematics of the Galactic Core-Collapse Supernova Remnant G292.0+1.8

    NASA Astrophysics Data System (ADS)

    Bhalerao, Jayant; Park, Sangwook; Dewey, Daniel; Hughes, John P.; Mori, Koji; Lee, Jae-Joon

    2015-02-01

    We report on the results from the analysis of our 114 ks Chandra High Energy Transmision Grating Spectrometer observation of the Galactic core-collapse supernova remnant G292.0+1.8. To probe the three-dimensional structure of the clumpy X-ray emitting ejecta material in this remnant, we measured Doppler shifts in emission lines from metal-rich ejecta knots projected at different radial distances from the expansion center. We estimate radial velocities of ejecta knots in the range of -2300 lsim vr lsim 1400 km s-1. The distribution of ejecta knots in velocity versus projected-radius space suggests an expanding ejecta shell with a projected angular thickness of ~90'' (corresponding to ~3 pc at d = 6 kpc). Based on this geometrical distribution of the ejecta knots, we estimate the location of the reverse shock approximately at the distance of ~4 pc from the center of the supernova remnant, putting it in close proximity to the outer boundary of the radio pulsar wind nebula. Based on our observed remnant dynamics and the standard explosion energy of 1051 erg, we estimate the total ejecta mass to be lsim8 M ⊙, and we propose an upper limit of lsim35 M ⊙ on the progenitor's mass.

  17. Effect of adhesive remnant removal on enamel topography after bracket debonding

    PubMed Central

    Cardoso, Larissa Adrian Meira; Valdrighi, Heloísa Cristina; Vedovello, Mario; Correr, Américo Bortolazzo

    2014-01-01

    INTRODUCTION: At orthodontic treatment completion, knowledge about the effects of adhesive remnant removal on enamel is paramount. OBJECTIVE: This study aimed at assessing the effect of different adhesive remnant removal methods on enamel topography (ESI) and surface roughness (Ra) after bracket debonding and polishing. METHODS: A total of 50 human premolars were selected and divided into five groups according to the method used for adhesive remnant removal: high speed tungsten carbide bur (TCB), Sof-Lex discs (SL), adhesive removing plier (PL), ultrasound (US) and Fiberglass burs (FB). Metal brackets were bonded with Transbond XT, stored at 37oC for 24 hours before debonding with adhesive removing plier. Subsequently, removal methods were carried out followed by polishing with pumice paste. Qualitative and quantitative analyses were conducted with pre-bonding, post-debonding and post-polishing analyses. Results were submitted to statistical analysis with F test (ANOVA) and Tukey's (Ra) as well as with Kruskal-Wallis and Bonferroni tests (ESI) (P < 0.05). RESULTS: US Ra and ESI were significantly greater than TCB, SL, PL and FB. Polishing minimized Ra and ESI in the SL and FB groups. CONCLUSION: Adhesive remnant removal with SL and FB associated with polishing are recommended due to causing little damage to the enamel. PMID:25628087

  18. Modelling Hard Gamma-Ray Emission from Supernova Remnants

    NASA Technical Reports Server (NTRS)

    Baring, Matthew G.

    1999-01-01

    The observation by the CANGAROO (Collaboration of Australia and Nippon Gamma Ray Observatory at Outback) experiment of TeV emission from SN 1006, in conjunction with several instances of non-thermal X-ray emission from supernova remnants, has led to inferences of super-TeV electrons in these extended sources. While this is sufficient to propel the theoretical community in their modelling of particle acceleration and associated radiation, the anticipated emergence in the next decade of a number of new experiments probing the TeV and sub-TeV bands provides further substantial motivation for modellers. In particular, the quest for obtaining unambiguous gamma-ray signatures of cosmic ray ion acceleration defines a "Holy Grail" for observers and theorists alike. This review summarizes theoretical developments in the prediction of MeV-TeV gamma-rays from supernova remnants over the last five years, focusing on how global properties of models can impact, and be impacted by, hard gamma-ray observational programs, thereby probing the supernova remnant environment. Properties of central consideration include the maximum energy of accelerated particles, the density of the unshocked interstellar medium, the ambient magnetic field, and the relativistic electron-to-proton ratio. Criteria for determining good candidate remnants for observability in the TeV band are identified.

  19. Supernova remnant S 147 and its associated neutron star(s)

    NASA Astrophysics Data System (ADS)

    Gvaramadze, V. V.

    2006-07-01

    The supernova remnant S 147 harbors the pulsar PSR J 0538+2817 whose characteristic age is more than an order of magnitude greater than the kinematic age of the system (inferred from the angular offset of the pulsar from the geometric center of the supernova remnant and the pulsar proper motion). To reconcile this discrepancy we propose that PSR J 0538+2817 could be the stellar remnant of the first supernova explosion in a massive binary system and therefore could be as old as its characteristic age. Our proposal implies that S 147 is the diffuse remnant of the second supernova explosion (that disrupted the binary system) and that a much younger second neutron star (not necessarily manifesting itself as a radio pulsar) should be associated with S 147. We use the existing observational data on the system to suggest that the progenitor of the supernova that formed S 147 was a Wolf-Rayet star (so that the supernova explosion occurred within a wind bubble surrounded by a massive shell) and to constrain the parameters of the binary system. We also restrict the magnitude and direction of the kick velocity received by the young neutron star at birth and find that the kick vector should not strongly deviate from the orbital plane of the binary system.

  20. Numerical Simulations of Supernova Remnant Evolution in a Cloudy Interstellar Medium

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Slavin, Jonathan D.; Smith, Randall K.; Foster, Adam

    The mixed morphology class of supernova remnants has centrally peaked X-ray emission along with a shell-like morphology in radio emission. White and Long proposed that these remnants are evolving in a cloudy medium wherein the clouds are evaporated via thermal conduction once being overrun by the expanding shock. Their analytical model made detailed predictions regarding temperature, density, and emission profiles as well as shock evolution. We present numerical hydrodynamical models in 2D and 3D including thermal conduction, testing the White and Long model and presenting results for the evolution and emission from remnants evolving in a cloudy medium. We findmore » that, while certain general results of the White and Long model hold, such as the way the remnants expand and the flattening of the X-ray surface brightness distribution, in detail there are substantial differences. In particular we find that the X-ray luminosity is dominated by emission from shocked cloud gas early on, leading to a bright peak, which then declines and flattens as evaporation becomes more important. In addition, the effects of thermal conduction on the intercloud gas, which is not included in the White and Long model, are important and lead to further flattening of the X-ray brightness profile as well as lower X-ray emission temperatures.« less

  1. Age-Related Differences in Anterior Cruciate Ligament Remnant Vascular-Derived Cells.

    PubMed

    Uefuji, Atsuo; Matsumoto, Tomoyuki; Matsushita, Takehiko; Ueha, Takeshi; Zhang, Shurong; Kurosaka, Masahiro; Kuroda, Ryosuke

    2014-06-01

    The anterior cruciate ligament (ACL) does not heal spontaneously after injury, and patients of different ages respond differently to treatment. CD34+ stem/progenitor cells derived from the ACL remnant and associated tissues contribute to tendon-bone healing, but the relationship between age and the ACL's healing potential has not been clarified. The ACL remnant and associated tissues from adolescent patients have more CD34+ cells, and this population of cells from younger patients exhibits a higher potential for proliferation and differentiation in vitro. Descriptive laboratory study. Ruptured ACL remnants and associated tissues were harvested from 28 patients (mean age, 24.6 ± 1.6 years) who had undergone primary arthroscopic ACL reconstruction. Patients were divided into 3 patient groups by age: 10-19 years (teens group; n = 10), 20-29 years (20s group; n = 10), and ≥30 years (30s group; n = 8). The ACL remnant cells were characterized using fluorescence-activated cell sorting (FACS). Expansion potential was evaluated using population doubling (PD), and multilineage differentiation potential was assessed and compared. The FACS analysis showed numerous CD34+ cells in the teens group compared with the 30s group (mean, 25.4% ± 7.9% vs 16.9% ± 3.9%, respectively; P = .044). The PD results indicated that the teens group had a significantly higher expansion potential than the 30s group at passage 3 (mean, 3.3 ± 0.2 vs 2.8 ± 0.2, respectively; P = .039). Young ACL remnant cells had a higher potential for osteogenic differentiation according to alkaline phosphatase activity (teens group, 169.5 ± 37.9 × 10 ng/mL vs 30s group, 64.9 ± 14.6 × 10 ng/mL; P = .029) and osteocalcin gene expression (teens group, 1.0 ± 0.25 vs 30s group, 0.39 ± 0.01; P = .01). In addition, the teens group displayed a higher differentiation potential to angiogenic lineages (acetylated low-density lipoprotein/Ulex europaeus lectin-stained cell counts) than other groups (teens group, 15.9 ± 1.9 vs 20s group, 8.9 ± 1.3 [P = .04]; teens group, 15.9 ± 1.9 vs 30s group, 7.2 ± 1.5 [P = .008]) and also tube length (teens group, 6939 ± 470 μm vs 30s group, 4119 ± 507 μm; P = .009). The ACL remnants of adolescent patients had more CD34+ cells, and those cells had a higher potential for proliferation and multilineage differentiation in vitro. During remnant-preserving or remnant-transplanted ACL reconstruction, surgeons should consider the patient's age when predicting the healing potential. © 2014 The Author(s).

  2. Ozone affects leaf physiology and causes injury to foliage of native tree species from the tropical Atlantic Forest of southern Brazil.

    PubMed

    Moura, Bárbara Baêsso; Alves, Edenise Segala; Marabesi, Mauro Alexandre; de Souza, Silvia Ribeiro; Schaub, Marcus; Vollenweider, Pierre

    2018-01-01

    In southern Brazil, the recent increase in tropospheric ozone (O 3 ) concentrations poses an additional threat to the biodiverse but endangered and fragmented remnants of the Atlantic Forest. Given the mostly unknown sensitivity of tropical species to oxidative stress, the principal objective of this study was to determine whether the current O 3 levels in the Metropolitan Region of Campinas (MRC), downwind of São Paulo, affect the native vegetation of forest remnants. Foliar responses to O 3 of three tree species typical of the MRC forests were investigated using indoor chamber exposure experiments under controlled conditions and a field survey. Exposure to 70ppb O 3 reduced assimilation and leaf conductance but increased respiration in Astronium graveolens while gas exchange in Croton floribundus was little affected. Both A. graveolens and Piptadenia gonoacantha developed characteristic O 3 -induced injury in the foliage, similar to visible symptoms observed in >30% of trees assessed in the MRC, while C. floribundus remained asymptomatic. The underlying structural symptoms in both O 3 -exposed and field samples were indicative of oxidative burst, hypersensitive responses, accelerated cell senescence and, primarily in field samples, interaction with photo-oxidative stress. The markers of O 3 stress were thus mostly similar to those observed in other regions of the world. Further research is needed, to estimate the proportion of sensitive forest species, the O 3 impact on tree growth and stand stability and to detect O 3 hot spots where woody species in the Atlantic Forest are mostly affected. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Food and symptom generation in functional gastrointestinal disorders: physiological aspects.

    PubMed

    Farré, Ricard; Tack, Jan

    2013-05-01

    The response of the gastrointestinal tract (GIT) to ingestion of food is a complex and closely controlled process, which allows optimization of propulsion, digestion, absorption of nutrients, and removal of indigestible remnants. This review summarizes current knowledge on the mechanisms that control the response of the GIT to food intake. During the cephalic phase, triggered by cortical food-related influences, the GIT prepares for receiving nutrients. The gastric phase is dominated by the mechanical effect of the meal volume. Accumulation of food in the stomach activates tension-sensitive mechanoreceptors, which in turn stimulate gastric accommodation and gastric acid secretion through the intrinsic and vago-vagal reflex pathways. After meal ingestion, the tightly controlled process of gastric emptying starts, with arrival of nutrients in the duodenum triggering negative feedback on emptying and stimulating secretion of digestive enzymes through the neural (mainly vago-vagal reflex, but also intrinsic) and endocrine (release of peptides from entero-endocrine cells) pathways. Several types of specialized receptors detect the presence of all main categories of nutrients. In addition, the gastrointestinal mucosa expresses receptors of the T1R and T2R families (taste receptors) and several members of the transient receptor potential channel family, all of which are putatively involved in the detection of specific tastants in the lumen. Activation of nutrient and taste sensors also activates the extrinsic and intrinsic neural, as well as entero-endocrine, pathways. During passage through the small bowel, nutrients are progressively extracted, and electrolyte-rich liquid intestinal content with non-digestible residue is delivered to the colon. The colon provides absorption of the water and electrolytes, storage of non-digestible remnants of food, aboral propulsion of contents, and finally evacuation through defecation.

  4. 22. Detail of remnants of winch and motor on remains ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. Detail of remnants of winch and motor on remains of machinery house platform east of drawspan; note cables (still connected to drawspan) coming off the winding drum; view to north. - Summer Street Bridge, Spanning Reserved Channel, Boston, Suffolk County, MA

  5. CE-MRA for follow-up of aneurysms post stent-assisted coiling.

    PubMed

    Agid, R; Schaaf, M; Farb, Ri

    2012-09-01

    This study compared the accuracy of contrast-enhanced MR angiography (CE-MRA) to intra-arterial cerebral angiography (IA-DSA) for assessment of intracranial aneurysms after stent-assisted coiling and to check if the presence of a stent in the parent artery diminishes the accuracy of CE-MRA. Consecutive patients with cerebral aneurysms treated by stent-assisted coiling were evaluated retrospectively. Matching follow-up CE-MRA and IA-DSA were evaluated separately. Evaluation included the presence of aneurysmal remnant, patency and stenosis of parent artery. Twenty-seven patients with 28 aneurysms and 33 matched CE-MRA and IA-DSA studies were evaluated. Nineteen aneurysmal remnants were seen on CE-MRA and 16 on IA-DSA. CE-MRA diagnosed three aneurysmal remnants not appreciated on IA-DSA. Five other remnants were larger on CE-MRA than IA-DSA. None of the remnants were missed on CE-MRA. Parent arteries were patent on both modalities. CE-MRA showed false stenosis of the stented artery in six cases and exaggerated stenosis in two. In 18 cases, CE-MRA showed a short focal "pseudo-stenosis" where the stent's marker bands were located. This was noted whenever the stent's marker bands were located in an artery with luminal diameter ≤2 mm and was called "marker band effect". CE-MRA is an accurate technique for follow-up of aneurysms post stent-assisted coiling with excellent depiction of remnants in spite of the presence of a stent. Apparent stenosis of the stented parent artery on CE-MRA is often false or exaggerated. "Marker band effect" should be recognized as an artifact that appears when stent's marker bands are in a small artery.

  6. CE-MRA for Follow-up of Aneurysms Post Stent-Assisted Coiling

    PubMed Central

    Agid, R.; Schaaf, M.; Farb, RI.

    2012-01-01

    Summary This study compared the accuracy of contrast-enhanced MR angiography (CE-MRA) to intra-arterial cerebral angiography (IA-DSA) for assessment of intracranial aneurysms after stent-assisted coiling and to check if the presence of a stent in the parent artery diminishes the accuracy of CE-MRA. Consecutive patients with cerebral aneurysms treated by stent-assisted coiling were evaluated retrospectively. Matching follow-up CE-MRA and IA-DSA were evaluated separately. Evaluation included the presence of aneurysmal remnant, patency and stenosis of parent artery. Twenty-seven patients with 28 aneurysms and 33 matched CE-MRA and IA-DSA studies were evaluated. Nineteen aneurysmal remnants were seen on CE-MRA and 16 on IA-DSA. CE-MRA diagnosed three aneurysmal remnants not appreciated on IA-DSA. Five other remnants were larger on CE-MRA than IA-DSA. None of the remnants were missed on CE-MRA. Parent arteries were patent on both modalities. CE-MRA showed false stenosis of the stented artery in six cases and exaggerated stenosis in two. In 18 cases, CE-MRA showed a short focal “pseudo-stenosis” where the stent’s marker bands were located. This was noted whenever the stent’s marker bands were located in an artery with luminal diameter ≤2 mm and was called “marker band effect”. CE-MRA is an accurate technique for follow-up of aneurysms post stent-assisted coiling with excellent depiction of remnants in spite of the presence of a stent. Apparent stenosis of the stented parent artery on CE-MRA is often false or exaggerated. “Marker band effect” should be recognized as an artifact that appears when stent’s marker bands are in a small artery. PMID:22958765

  7. Cervical chondrocutaneous branchial remnants--report of 17 cases.

    PubMed

    Begovic, Ninoslav; Simic, Radoje; Vlahovic, Aleksandar; Kravljanac, Djordje; Djuricic, Slavisa; Mijovic, Tanja

    2014-11-01

    Cervical chondrocutaneous branchial remnants are congenital, benign and rare neck masses. These anomalies are limited in the literature, reported mostly as case reports. Cervical chondrocutaneous branchial remnant is always present at birth, and the lesion is usually unilateral. Understanding and treatment of cervical chondrocutaneous branchial remnants requires knowledge of the related embryology. From January 2005 to December 2008, 17 patients with mean age of 32 months (range from 2 months to 15 years) with CCBRs were treated at the Division of Pediatric Surgery, Department of Plastic and Reconstructive Surgery and Burns at the Institute for Mother and Child Health Care, Belgrade, Serbia. The following objections were recorded: sex, lesion side, surgical data, associated malformations and pathohistology findings. There were 7 females and 10 males, 4 with bilateral presences. Five children had associated anomalies, as follows: vesicoureteral reflux, atrial and ventricular septal defect, ventricular septal defect, branchiootorenal syndrome and preauricular sinus. There was a positive family history in one patient. Fifteen patients (88%) were treated with complete surgical excision and no connections with deep underlying structures of the neck were found. There were no complications at surgery. No recurrence was found during follow-up. Histopathology analysis revealed both, hyaline and elastic cartilage. Cervical chondrocutaneous branchial remnants are rare anomalies arising from branchial arch, probably originally from remnants of first or second arch. Surgical excision is the treatment of choice. From our experience, we suggest surgical treatment early in childhood because of esthetic reason, simplicity of the intervention and low complication rate. Also, the abdominal ultrasound and cardiac examination is recommended because of associated anomalies. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  8. The evolving instability of the remnant Larsen B Ice Shelf and its tributary glaciers

    NASA Astrophysics Data System (ADS)

    Khazendar, Ala; Borstad, Christopher P.; Scheuchl, Bernd; Rignot, Eric; Seroussi, Helene

    2015-06-01

    Following the 2002 disintegration of the northern and central parts of the Larsen B Ice Shelf, the tributary glaciers of the southern surviving part initially appeared relatively unchanged and hence assumed to be buttressed sufficiently by the remnant ice shelf. Here, we modify this perception with observations from IceBridge altimetry and InSAR-inferred ice flow speeds. Our analyses show that the surfaces of Leppard and Flask glaciers directly upstream from their grounding lines lowered by 15 to 20 m in the period 2002-2011. The thinning appears to be dynamic as the flow of both glaciers and the remnant ice shelf accelerated in the same period. Flask Glacier started accelerating even before the 2002 disintegration, increasing its flow speed by ∼55% between 1997 and 2012. Starbuck Glacier meanwhile did not change much. We hypothesize that the different evolutions of the three glaciers are related to their dissimilar bed topographies and degrees of grounding. We apply numerical modeling and data assimilation that show these changes to be accompanied by a reduction in the buttressing afforded by the remnant ice shelf, a weakening of the shear zones between its flow units and an increase in its fracture. The fast flowing northwestern part of the remnant ice shelf exhibits increasing fragmentation, while the stagnant southeastern part seems to be prone to the formation of large rifts, some of which we show have delimited successive calving events. A large rift only 12 km downstream from the grounding line is currently traversing the stagnant part of the ice shelf, defining the likely front of the next large calving event. We propose that the flow acceleration, ice front retreat and enhanced fracture of the remnant Larsen B Ice Shelf presage its approaching demise.

  9. Searching for the Remnants of Southern Seas: Cassini Observations of the South Pole of Titan

    NASA Astrophysics Data System (ADS)

    Stofan, Ellen R.; Aharonson, O.; Hayes, A. G.; Kirk, R.; Lopes, R.; Lorenz, R. D.; Lucas, A.; Lunine, J. I.; Malaska, M.; Radebaugh, J.; Stiles, B. W.; Turtle, E. P.; Wall, S. D.; Wood, C. A.; Cassini Radar Team

    2012-10-01

    The north polar region of Titan is home to three large seas along with hundreds of smaller lakes, while the south pole apparently has only two partially filled basins of liquid hydrocarbons. Aharonson et al. [2009] has suggested that cycles analogous to Croll-Milankovich cycles on Earth cause long-term cyclic transfer of hydrocarbons from pole to pole, with the north pole now containing the bulk of the liquids. Less than 50,000 years ago, the cycle would have been reversed, suggesting that the south polar region should contain remnants of southern seas. To identify such seas, we search for features enclosed by an apparent remnant shoreline, with an interior region of smooth (radar-dark) plains. Two such features can be readily identified, each with areal extents of over 100,000 km2, along with several other possible candidate remnant seas or large lakes. One of the possible seas now contains Ontario Lacus. Analysis of the morphologic and topographic characteristics of the two candidate remnant seas can help constrain the possible depth and basin characteristics of the northern seas, as well as possible rates of surface modification in the time since the seas have (largely) dried up. In addition, analysis of the radar characteristics of the remnant sea basins may help us to determine if such processes also acted at equatorial regions where evidence of rainfall [Turtle et al., 2011] and a possible lake has recently been presented [Griffith et al., 2012], and at the more homogeneous mid-latitudes on Titan. References: Aharonson, O. et al., Nature Geoscience 2, 851-854; Griffith, C. et al., Nature 486, 237-239; Turtle, E.P. et al., Science 331, 1414-1417.

  10. The effects of two soft drinks on bond strength, bracket microleakage, and adhesive remnant on intact and sealed enamel.

    PubMed

    Navarro, Raúl; Vicente, Ascensión; Ortiz, Antonio J; Bravo, Luis A

    2011-02-01

    The purpose of this study was to evaluate the effects of Coca-Cola and Schweppes Limón on bond strength, adhesive remnant, and microleakage beneath brackets. One hundred and twenty upper central incisor brackets were bonded to bovine incisors and divided into three groups: (1) Control, (2) Coca-Cola, and (3) Schweppes Limón. The teeth were submerged in the drinks three times a day for 15 minutes over a 15 day period. Shear bond strength (SBS) was measured with a universal testing machine, and adhesive remnant evaluated using image analysis equipment. Microleakage at the enamel-adhesive and adhesive-bracket interfaces was determined using methylene blue. One hundred and eight teeth were used for scanning electron microscopy to determine the effect of the drinks on intact and sealed enamel. SBS and adhesive remnant data were analysed using the Kruskal-Wallis test (P < 0.05) and microleakage using the Kruskal-Wallis and Mann-Whitney tests applying Bonferroni correction (P < 0.017). No significant differences were found in SBS and adhesive remnant between the groups (P > 0.05). Microleakage at the enamel-adhesive interface for groups 2 and 3 was significantly greater than for group 1 (P < 0.017). At the adhesive-bracket interface, microleakage was significantly greater in group 2 than in group 1 (P < 0.017) while microleakage in group 3 did not differ significantly from either group 1 or 2 (P < 0.017). The drinks produced enamel erosion, loss of adhesive and microleakage. Coca-Cola and Schweppes Limón did not affect the SBS of brackets or the adhesive remnant.

  11. Meteorological Station, interior with collapsed roof showing remnant wooden equipment ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Meteorological Station, interior with collapsed roof showing remnant wooden equipment switch box on east wall; view southeast - Fort McKinley, Meteorological Station, East side of Weymouth Way, approximately 225 feet south of Cove Side Drive, Great Diamond Island, Portland, Cumberland County, ME

  12. Excitation and Disruption of a Giant Molecular Cloud by the Sepurnova Remnant 3C 391

    NASA Technical Reports Server (NTRS)

    Reach, W. T.; Rho, J.

    1998-01-01

    The ambient molecular gas at the distance of the remnant comprises a giant molecular cloud whose edge is closely parallel to a ridge of bright non-thermal radio continuum, which evidently delineates the blast-wave into the cloud.

  13. 15. CYLINDRICAL FISH SCALER Remnants of the wire screen remain, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. CYLINDRICAL FISH SCALER Remnants of the wire screen remain, through which the fish tumbled as the cylinder revolved. Note geared ring around cylinder, and the small drive shaft by which it was driven. - Hovden Cannery, 886 Cannery Row, Monterey, Monterey County, CA

  14. Mechanical stress modified ferroelectric aging behavior

    NASA Astrophysics Data System (ADS)

    Xu, Tingting; Kan, Yi; Jin, Yaming; Sun, Hui; Du, Yingchao; Wu, Xiumei; Bo, Huifeng; Cai, Wei; Huang, Fengzhen; Lu, Xiaomei; Zhu, Jinsong

    2013-05-01

    Mechanical stress effect on aging behavior of Bi3.25La0.75Ti3O12 (BLT) and PbZr0.53Ti0.47O3 (PZT) films was investigated. It is found that the remnant polarization decreases with time while the coercive field increases in stress-free BLT films. For unconfined PZT films, both the remnant polarization and the coercive field decrease as time elapses. The applied tensile stress weakens the aging of remnant polarization of BLT films but strengthens the aging of coercive field, while the applied tensile stress possesses opposite effect. In contrary, the applied compressive stress simultaneously improves the aging behavior of both remnant polarization and coercive field of PZT films. Mechanical-stress-induced variation of domain wall mobility in different materials was suggested as the possible origin of these observations. This work indicates that the aging behavior modification using stress could be realized, and it is helpful for promoting the reliability of ferroelectric films for industrial applications.

  15. H-alpha images of the Cygnus Loop - A new look at shock-wave dynamics in an old supernova remnant

    NASA Technical Reports Server (NTRS)

    Fesen, Robert A.; Kwitter, Karen B.; Downes, Ronald A.

    1992-01-01

    Attention is given to deep H-alpha images of portions of the east, west, and southwest limbs of the Cygnus Loop which illustrate several aspects of shock dynamics in a multiphase interstellar medium. An H-alpha image of the isolated eastern shocked cloud reveals cloud deformation and gas stripping along the cloud's edges, shock front diffraction and reflection around the rear of the cloud, and interior remnant emission due to upstream shock reflection. A faint Balmer-dominated filament is identified 30 arcmin further west of the remnant's bright line of western radiative filaments. This detection indicates a far more westerly intercloud shock front position than previously realized, and resolves the nature of the weak X-ray, optical, and nonthermal radio emission observed west of NGC 6960. Strongly curved Balmer-dominated filaments along the remnant's west and southwest edge may indicate shock diffraction caused by shock wave passage in between clouds.

  16. XMM-Newton observations of the non-thermal supernova remnant HESS J1731-347 (G353.6-0.7)

    NASA Astrophysics Data System (ADS)

    Doroshenko, V.; Pühlhofer, G.; Bamba, A.; Acero, F.; Tian, W. W.; Klochkov, D.; Santangelo, A.

    2017-12-01

    We report on the analysis of XMM-Newton observations of the non-thermal shell-type supernova remnant HESS J1731-347 (G353.6-0.7). For the first time the complete remnant shell has been covered in X-rays, which allowed direct comparison with radio and TeV observations. We carried out a spatially resolved spectral analysis of XMM-Newton data and confirmed the previously reported non-thermal power-law X-ray spectrum of the source with negligible variations of spectral index across the shell. On the other hand, the X-ray absorption column is strongly variable and correlates with the CO emission thus confirming that the absorbing material must be in the foreground and reinforcing the previously suggested lower limit on distance. Finally, we find that the X-ray emission of the remnant is suppressed towards the Galactic plane, which points to lower shock velocities in this region, likely due to the interaction of the shock with the nearby molecular cloud.

  17. Bridging the gap between supernovae and their remnants through multi-dimensional hydrodynamic modeling

    NASA Astrophysics Data System (ADS)

    Orlando, S.; Miceli, M.; Petruk, O.

    2017-02-01

    Supernova remnants (SNRs) are diffuse extended sources characterized by a complex morphology and a non-uniform distribution of ejecta. Such a morphology reflects pristine structures and features of the progenitor supernova (SN) and the early interaction of the SN blast wave with the inhomogeneous circumstellar medium (CSM). Deciphering the observations of SNRs might open the possibility to investigate the physical properties of both the interacting ejecta and the shocked CSM. This requires accurate numerical models which describe the evolution from the SN explosion to the remnant development and which connect the emission properties of the remnants to the progenitor SNe. Here we show how multi-dimensional SN-SNR hydrodynamic models have been very effective in deciphering observations of SNR Cassiopeia A and SN 1987A, thus unveiling the structure of ejecta in the immediate aftermath of the SN explosion and constraining the 3D pre-supernova structure and geometry of the environment surrounding the progenitor SN.

  18. X-ray studies of supernova remnants: A different view of supernova explosions

    PubMed Central

    Badenes, Carles

    2010-01-01

    The unprecedented spatial and spectral resolutions of Chandra have revolutionized our view of the X-ray emission from supernova remnants. The excellent datasets accumulated on young, ejecta-dominated objects like Cas A or Tycho present a unique opportunity to study at the same time the chemical and physical structure of the explosion debris and the characteristics of the circumstellar medium sculpted by the progenitor before the explosion. Supernova remnants can thus put strong constraints on fundamental aspects of both supernova explosion physics and stellar evolution scenarios for supernova progenitors. This view of the supernova phenomenon is completely independent of, and complementary to, the study of distant extragalactic supernovae at optical wavelengths. The calibration of these two techniques has recently become possible thanks to the detection and spectroscopic follow-up of supernova light echoes. In this paper, I review the most relevant results on supernova remnants obtained during the first decade of Chandra and the impact that these results have had on open issues in supernova research. PMID:20404206

  19. SNR 1E0102.2-7219 after Six Years with Chandra

    NASA Astrophysics Data System (ADS)

    Rutkowski, M. J.; Schlegel, E. M.; Keohane, J.

    2005-12-01

    We present Chandra X-ray Observatory archived observations of the supernova remnant 1E0102.2-7219 in the Small Magellanic Cloud. Combining 22 ACIS-I observations for 230 ks of total exposure time, we present ACIS images with an unprecedented signal to noise ratio for this remnant. We present three upper limits on the X-ray flux for the remnant's elusive central compact object, which are consistent with current neutron star cooling models, based on a Cas A-like blackbody spectrum. Additionally, we discuss the elliptical structure of the remnant and the relative positions of the blast wave, the reverse shock, and the extent of 1E0102.2-7219's rim. This research was supported by the NSF REU Program at SAO under Eric Schlegel, whose research was supported by contract number NAS8-39073 from NASA to SAO for operation of the Chandra X-Ray Observatory. Jonathan Keohane's research was supported by Chandra award GO3-4070C.

  20. Time evolution of gamma rays from supernova remnants

    NASA Astrophysics Data System (ADS)

    Gaggero, Daniele; Zandanel, Fabio; Cristofari, Pierre; Gabici, Stefano

    2018-04-01

    We present a systematic phenomenological study focused on the time evolution of the non-thermal radiation - from radio waves to gamma rays - emitted by typical supernova remnants via hadronic and leptonic mechanisms, for two classes of progenitors: thermonuclear and core-collapse. To this aim, we develop a numerical tool designed to model the evolution of the cosmic ray spectrum inside a supernova remnant, and compute the associated multi-wavelength emission. We demonstrate the potential of this tool in the context of future population studies based on large collection of high-energy gamma-ray data. We discuss and explore the relevant parameter space involved in the problem, and focus in particular on their impact on the maximum energy of accelerated particles, in order to study the effectiveness and duration of the PeVatron phase. We outline the crucial role of the ambient medium through which the shock propagates during the remnant evolution. In particular, we point out the role of dense clumps in creating a significant hardening in the hadronic gamma-ray spectrum.

  1. Olive oil increases the magnitude of postprandial chylomicron remnants compared to milk fat and safflower oil.

    PubMed

    Higashi, K; Ishikawa, T; Shige, H; Tomiyasu, K; Yoshida, H; Ito, T; Nakajima, K; Yonemura, A; Sawada, S; Nakamura, H

    1997-10-01

    The acute effects of olive oil, milk fat and safflower oil on postprandial lipemia and remnant lipoprotein metabolism were investigated. Eight Healthy male volunteers randomly underwent three types of oral fat-vitamin A loading tests. The test drink was a mixture of retinyl palmitate (RP)(50,000 IU of aqueous vitamin A/m2 body surface area) and one of the three types of oils (40 g of fat/m2 body surface area): olive oil (70.7% oleic acid of total fatty acids); milk fat (69.3% saturated fatty acid); safflower oil (74.2% linoleic acid). Olive oil significantly increased plasma triacylglycerol and RP concentrations 4 hours after fat loading, as compared to other fats. Increases of remnant like particle concentrations were higher after olive oil than after the other two fats. These results show that olive oil increases the magnitude of postprandial chylomicrons and chylomicron remnants compared to milk fat and safflower oil.

  2. G0.9 + 0.1 and the emerging class of composite supernova remnants

    NASA Technical Reports Server (NTRS)

    Helfand, D. J.; Becker, R. H.

    1987-01-01

    High-resolution, multifrequency maps of a bright extended radio source near the Galactic center have revealed it to be a classic example of a composite supernova remnant. A steep-spectrum shell of emission, about 8 arcmin in diameter, surrounds a flat-spectrum, highly polarized Crab-like core about 2 arcmin across. The two components have equal flux densities at about 6 cm, marking this source as having the highest core-to-shell ratio among the about 10 composite remnants identified to date. X-ray and far-infrared data on the source are used to constrain the energetics and evolutionary state of the remnant and its putative central pulsar. It is argued that the total energy contained in the Crab-like components requires that the pulsars powering them were all born with periods shorter than 50 ms, and that if a substantial number of neutron stars with slow initial rotation rates exist, their birthplaces have not yet been found.

  3. Generation, Characterization and Application of Antibodies Directed against HERV-H Gag Protein in Colorectal Samples.

    PubMed

    Mullins, Christina S; Hühns, Maja; Krohn, Mathias; Peters, Sven; Cheynet, Valérie; Oriol, Guy; Guillotte, Michèle; Ducrot, Sandrine; Mallet, François; Linnebacher, Michael

    2016-01-01

    A substantial part of the human genome originates from transposable elements, remnants of ancient retroviral infections. Roughly 8% of the human genome consists of about 400,000 LTR elements including human endogenous retrovirus (HERV) sequences. Mainly, the interplay between epigenetic and post-transcriptional mechanisms is thought to silence HERV expression in most physiological contexts. Interestingly, aberrant reactivation of several HERV-H loci appears specific to colorectal carcinoma (CRC). The expression of HERV-H Gag proteins (Gag-H) was assessed using novel monoclonal mouse anti Gag-H antibodies. In a flow cytometry screen four antibody clones were tested on a panel of primary CRC cell lines and the most well performing ones were subsequently validated in western blot analysis. Finally, Gag-H protein expression was analyzed by immune histology on cell line cytospins and on clinical samples. There, we found a heterogeneous staining pattern with no background staining of endothelial, stromal and infiltrating immune cells but diffuse staining of the cytoplasm for positive tumor and normal crypt cells of the colonic epithelium. Taken together, the Gag-H antibody clone(s) present a valuable tool for staining of cells with colonic origin and thus form the basis for future more detailed investigations. The observed Gag-H protein staining in colonic epithelium crypt cells demands profound analyses of a potential role for Gag-H in the normal physiology of the human gut.

  4. The effect of different concentrations of copper and lead on the morphology and physiology of Hypnea musciformis cultivated in vitro: a comparative analysis.

    PubMed

    Santos, Rodrigo W; Schmidt, Éder C; Vieira, Izabela C; Costa, Giulia B; Rover, Ticiane; Simioni, Carmen; Barufi, José Bonomi; Soares, Carlos Henrique L; Bouzon, Zenilda L

    2015-09-01

    Copper and lead, as remnants of industrial activities and urban effluents, have heavily contaminated many aquatic environments. Therefore, this study aimed to determine their effects on the physiological, biochemical, and cell organization responses of Hypnea musciformis under laboratory conditions during a 7-day experimental period. To accomplish this, segments of H. musciformis were exposed to photosynthetic active radiation at 80 μmol photons m(-2) s(-1), Cu (0.05 and 0.1 mg kg(-1)), and Pb (3.5 and 7 mg kg(-1)). Various intracellular abnormalities resulted from exposure to Cu and Pb, including a decrease in phycobiliproteins. Moreover, carotenoid and flavonoid contents, as well as phenolic compounds, were decreased, an apparent reflection of chemical antioxidant defense against reactive oxygen species. Treatment with Cu and Pb also caused an increase in the number of floridean starch grains, probably as a defense against nutrient deprivation. Compared to plants treated with lead, those treated with copper showed higher metabolic and ultrastructural alterations. These results suggest that H. musciformis more readily internalizes copper through transcellular absorption. Finally, as a result of ultrastructural damage and metabolic changes observed in plants exposed to different concentrations of Cu and Pb, a significant reduction in growth rates was observed. Nevertheless, the results indicated different susceptibility of H. musciformis to different concentrations of Cu and Pb.

  5. Creating Simulated Microgravity Patient Models

    NASA Technical Reports Server (NTRS)

    Hurst, Victor; Doerr, Harold K.; Bacal, Kira

    2004-01-01

    The Medical Operational Support Team (MOST) has been tasked by the Space and Life Sciences Directorate (SLSD) at the NASA Johnson Space Center (JSC) to integrate medical simulation into 1) medical training for ground and flight crews and into 2) evaluations of medical procedures and equipment for the International Space Station (ISS). To do this, the MOST requires patient models that represent the physiological changes observed during spaceflight. Despite the presence of physiological data collected during spaceflight, there is no defined set of parameters that illustrate or mimic a 'space normal' patient. Methods: The MOST culled space-relevant medical literature and data from clinical studies performed in microgravity environments. The areas of focus for data collection were in the fields of cardiovascular, respiratory and renal physiology. Results: The MOST developed evidence-based patient models that mimic the physiology believed to be induced by human exposure to a microgravity environment. These models have been integrated into space-relevant scenarios using a human patient simulator and ISS medical resources. Discussion: Despite the lack of a set of physiological parameters representing 'space normal,' the MOST developed space-relevant patient models that mimic microgravity-induced changes in terrestrial physiology. These models are used in clinical scenarios that will medically train flight surgeons, biomedical flight controllers (biomedical engineers; BME) and, eventually, astronaut-crew medical officers (CMO).

  6. The protective effect of superoxide dismutase on isolated human mammary arteries preincubated with triglyceride-rich remnant lipoproteins.

    PubMed

    Savoiu, Germaine; Drăgan, Simona; Cristescu, Carmen; Serban, Corină; Noveanu, Lavinia; Ionescu, Daniela; Nicola, T; Duicu, Oana; Răducan, Andreea; Voicu, Mirela

    2009-01-01

    The main changes of the plasma lipid profile in patients with endothelial dysfunction are the increased triglyceride content of the lipoprotein remnant particles, the presence of the small and dense LDL particles and the decreasing of the HDL-cholesterol level. Considering these observations, we performed "in vitro" experiments using human mammary artery rings, in order to examine the effect of the lipoprotein "remnants" on endothelium-dependent vasodilatation induced by cumulative doses (10(-9) M - 10(-4) M) of adenosine (ADP) and to study the effect on endothelial--independent vasodilatation induced by cumulative doses (10(-9) M-10(-4) M) of sodium-nitropruside (NSP), respectively. Our results showed that 1 hour pre-incubation with triglyceride--rich lipoprotein remnants diminished the endothelial-dependent vasodilator response to ADP, but it has not modified the endothelial-independent vasodilator response to NSP. Vascular response was expressed as maximal vasodilatation from the 10(-4)M phenilephrine (PE) induced pre-contraction, considered as reference. In the case of ADP, the maximal vasodilatation was ranged in 36.50% +/- 10.81% interval, comparing with the control group that presented a maximal vasodilatation of 66.15% +/- 19.41% (p < 0.005). In the case of NSP the maximal vasodilatation was ranged in 99.78% +/- 10.53% interval, comparing with the control that presented a maximal vasodilatation of 98.99% +/- 12.45% (p = 0.44). One hour co-incubation of the rings with a solution containing lipoprotein remnants (1% oxidized IDL (ox-IDL) and antioxidant factor (150 U/mL 10(-4) M Superoxid dismutase (SOD) significantly reduced the impairment of the vasodilatation response to ADP. Maximal vasodilatation of ox-IDL and SOD coincubated human mammary artery rings was 58.50% +/- 10.63% compared to the control, were the maximal vasodilatation was 66.15% +/- 19.41% (p < 0.01), but has not modified the vasodilatation response to NSP (99% +/- 0.53% vs control 98.99% +/- 12.45%, p = 0.56). The endothelial dysfunction induced by the triglyceride-rich lipoprotein "remnants", could contribute to the pathogenesis of atherosclerosis and the treatment with high doses of antioxidants could "protect" the endothelium against the pro-atherogenic action of the lipoprotein "remnants".

  7. The utility of the apolipoprotein A1 remnant ratio in predicting incidence coronary heart disease in a primary prevention cohort: The Jackson Heart Study.

    PubMed

    May, Heidi T; Nelson, John R; Lirette, Seth T; Kulkarni, Krishnaji R; Anderson, Jeffrey L; Griswold, Michael E; Horne, Benjamin D; Correa, Adolfo; Muhlestein, Joseph B

    2016-05-01

    Dyslipidemia plays a significant role in the progression of cardiovascular disease. The apolipoprotein (apo) A1 remnant ratio (apo A1/VLDL3-C + IDL-C) has recently been shown to be a strong predictor of death/myocardial infarction risk among women >50 years undergoing angiography. However, whether this ratio is associated with coronary heart disease risk among other populations is unknown. We evaluated the apo A1 remnant ratio and its components for coronary heart disease incidence. Observational. Participants (N = 4722) of the Jackson Heart Study were evaluated. Baseline clinical characteristics and lipoprotein subfractions (Vertical Auto Profile method) were collected. Cox hazard regression analysis, adjusted by standard cardiovascular risk factors, was utilized to determine associations of lipoproteins with coronary heart disease. Those with new-onset coronary heart disease were older, diabetic, smokers, had less education, used more lipid-lowering medication, and had a more atherogenic lipoprotein profile. After adjustment, the apo A1 remnant ratio (hazard ratio = 0.67 per 1-SD, p = 0.002) was strongly associated with coronary heart disease incidence. This association appears to be driven by the IDL-C denominator (hazard ratio = 1.23 per 1-SD, p = 0.007). Remnants (hazard ratio = 1.21 per 1-SD, p = 0.017), but not apo A1 (hazard ratio = 0.85 per 1-SD, p = 0.121) or VLDL3-C (hazard ratio = 1.13 per 1-SD, p = 0.120) were associated with coronary heart disease. Standard lipids were not associated with coronary heart disease incidence. We found the apo A1 remnant ratio to be strongly associated with coronary heart disease. This ratio appears to better stratify risk than standard lipids, apo A1, and remnants among a primary prevention cohort of African Americans. Its utility requires further study as a lipoprotein management target for risk reduction. © The European Society of Cardiology 2015.

  8. Common Student Misconceptions in Exercise Physiology and Biochemistry

    ERIC Educational Resources Information Center

    Morton, James P.; Doran, Dominic A.; MacLaren, Don P. M.

    2008-01-01

    The present study represents a preliminary investigation designed to identify common misconceptions in students' understanding of physiological and biochemical topics within the academic domain of sport and exercise sciences. A specifically designed misconception inventory (consisting of 10 multiple-choice questions) was administered to a cohort…

  9. Geonic black holes and remnants in Eddington-inspired Born-Infeld gravity.

    PubMed

    Olmo, Gonzalo J; Rubiera-Garcia, D; Sanchis-Alepuz, Helios

    We show that electrically charged solutions within the Eddington-inspired Born-Infeld theory of gravity replace the central singularity by a wormhole supported by the electric field. As a result, the total energy associated with the electric field is finite and similar to that found in the Born-Infeld electromagnetic theory. When a certain charge-to-mass ratio is satisfied, in the lowest part of the mass and charge spectrum the event horizon disappears, yielding stable remnants. We argue that quantum effects in the matter sector can lower the mass of these remnants from the Planck scale down to the TeV scale.

  10. QUANTITATIVE EVALUATION OF THE HYPOTHESIS THAT BL LACERTAE OBJECTS ARE QSO REMNANTS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Borra, E. F.

    2014-11-20

    We evaluate with numerical simulations the hypothesis that BL Lacertae objects (BLLs) are the remnants of quasi-stellar objects. This hypothesis is based on their highly peculiar redshift evolution. They have a comoving space density that increases with decreasing redshift, contrary to all other active galactic nuclei. We assume that relativistic jets are below detection in young radio-quiet quasars and increase in strength with cosmic time so that they eventually are detected as BLLs. Our numerical simulations fit very well the observed redshift distributions of BLLs. There are strong indications that only the high-synchrotron-peaked BLLs could be QSO remnants.

  11. Determining Recoverable and Irrecoverable Contributions to Accumulated Strain in a NiTiPd High-Temperature Shape Memory Alloy During Thermomechanical Cycling

    NASA Technical Reports Server (NTRS)

    Monroe, J. A.; Karaman, I.; Lagoudas, D. C.; Bigelow, G.; Noebe, R. D.; Padula, S., II

    2011-01-01

    When Ni(29.5)Ti(50.5)Pd30 shape memory alloy is thermally cycled under stress, significant strain can accumulate due to elasticity, remnant oriented martensite and plasticity. The strain due to remnant martensite can be recovered by further thermal cycling under 0 MPa until the original transformation-induced volume change and martensite coefficient of thermal expansion are obtained. Using this technique, it was determined that the 8.15% total accumulated strain after cycling under 200 MPa consisted of 0.38%, 3.97% and 3.87% for elasticity, remnant oriented martensite and creep/plasticity, respectively.

  12. Discovery of a 50 millisecond pulsar in the Large Magellanic Cloud

    NASA Technical Reports Server (NTRS)

    Seward, F. D.; Harnden, F. R., Jr.; Helfand, D. J.

    1984-01-01

    The present investigation is concerned with the discovery of a new pulsed X-ray source in the Large Magellanic Cloud (LMC) supernova remnant 0540 - 693. The SNR 0540 - 693 is one of three suspected Crab-like remnants in the LMC. The existing X-ray, optical, and radio observations of the remnant itself are discussed, and an analysis is conducted of the implications of the period, period derivative, and X-ray pulse shape of the new source. It is concluded that the pulsed X-ray source is almost certainly a young, isolated pulsar. Many of its properties are very similar to those of the Crab pulsar.

  13. Surveying the South Pole-Aitken basin magnetic anomaly for remnant impactor metallic iron

    USGS Publications Warehouse

    Cahill, Joshua T.S.; Hagerty, Justin J.; Lawrence, David M.; Klima, Rachel L.; Blewett, David T.

    2014-01-01

    The Moon has areas of magnetized crust ("magnetic anomalies"), the origins of which are poorly constrained. A magnetic anomaly near the northern rim of South Pole-Aitken (SPA) basin was recently postulated to originate from remnant metallic iron emplaced by the SPA basin-forming impactor. Here, we remotely examine the regolith of this SPA magnetic anomaly with a combination of Clementine and Lunar Prospector derived iron maps for any evidence of enhanced metallic iron content. We find that these data sets do not definitively detect the hypothesized remnant metallic iron within the upper tens of centimeters of the lunar regolith.

  14. Early caregiving and physiological stress responses.

    PubMed

    Luecken, Linda J; Lemery, Kathryn S

    2004-05-01

    Inadequate early caregiving has been associated with risks of stress-related psychological and physical illness over the life span. Dysregulated physiological stress responses may represent a mechanism linking early caregiving to health outcomes. This paper reviews evidence linking early caregiving to physiological responses that can increase vulnerability to stress-related illness. A number of high-risk family characteristics, including high conflict, divorce, abuse, and parental psychopathology, are considered in the development of stress vulnerability. Three theoretical pathways linking caregiving to physiological stress responses are outlined: genetic, psychosocial, and cognitive-affective. Exciting preliminary evidence suggests that early caregiving can impact long-term physiological stress responses. Directions for future research in this area are suggested.

  15. The Supernova - A Stellar Spectacle.

    ERIC Educational Resources Information Center

    Straka, W. C.

    This booklet is part of an American Astronomical Society curriculum project designed to provide teaching materials to teachers of secondary school chemistry, physics, and earth science. The following topics concerning supernovae are included: the outburst as observed and according to theory, the stellar remnant, the nebular remnant, and a summary…

  16. 8. VIEW OF REMNANTS OF COULTERVILLE ROAD BELOW FORESTA. NOTE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. VIEW OF REMNANTS OF COULTERVILLE ROAD BELOW FORESTA. NOTE ASPHALT AT LEFT CENTER. NOTE RETAINING WALL AT RIGHT REAR. LOOKING NW. GIS: N-37 42 40.6 / W-119 43 27.6 - Coulterville Road, Between Foresta & All-Weather Highway, Yosemite Village, Mariposa County, CA

  17. Kepler Supernova Remnant: A View from Chandra X-Ray Observatory

    NASA Image and Video Library

    2004-10-06

    The images indicate that the bubble of gas that makes up the supernova remnant appears different in various types of light. Chandra reveals the hottest gas [colored blue and colored green], which radiates in X-rays. http://photojournal.jpl.nasa.gov/catalog/PIA06908

  18. Supernova Remnants As Laboratories For Determining The Properties Of Ejecta Dust And The Processing Of Dust Grains In Shocks

    NASA Astrophysics Data System (ADS)

    Dwek, Eli; Temim, Tea

    Recent infrared satellites, such as the Spitzer, Herschel, and WISE, have obtained a wealth of spectral and broadband data on the infrared (IR) emission from dust in supernova remnants (SNRs). Supernovae (SNe) are important producers of newly condensed dust during the early free-expansion phase of their evolution, and the dominant destroyers of dust during the subsequent remnant phase of their evolution. The infrared observations hold the key for determining their role in the origin and evolution of dust in the universe. We propose to model the composition, abundance, and size distribution of the dust in select Galactic and Magellanic Cloud remnants. As explained in detail below, the remnants were selected for the availability of IR and X-ray observations. All selected remnants have Spitzer IRS spectral data in the 5-35 μm regions which allow us to determine the effect of grain processing in the shock. Some have spectral maps that allow the distinction between the IR emission from SN-condensed and swept up circumstellar and interstellar dust. All remnants have also been covered by Spitzer, Herschel, and WISE imaging, and have existing X-ray Chandra and/or XMM observations. The dust in some remnants is radiatively-heated by a pulsar wind nebula, and in others collisionally- heated by shocked X-ray or line emitting gas. We will use physical models to calculate the radiative and collisional heating of SNR dust, the equilibrium or fluctuating dust temperatures, and the resulting IR emission for various dust compositions and size distributions. Specific examples of Cas A, SN1987A, the Crab Nebula, and Puppis A, are discussed in detail to illustrate our modeling approach. Our study will be the first comprehensive and physical analysis of a large sample of SNRs in different evolutionary states and different astrophysical environments. They will cover a wide range of interactions between the dust grains and their surroundings, including the radioactively- powered and/or shocked SN ejecta, hard X-rays and EUV radiation fields, and shocked circumstel- lar/interstellar gas. Our study will shed light on the evolution of dust grains from their explosive formation sites, through their violent injection into the ISM, and ultimate demise or survival as they travel through a network of interstellar shock waves. It will constitute a major advance in our understanding of the origin and evolution of dust in the Milky Way, in galaxies in general, and especially in the early universe.

  19. Cotton rats (Sigmodon hispidus) possess pharyngeal pouch remnants originating from different primordia.

    PubMed

    Nakamura, Teppei; Ichii, Osamu; Irie, Takao; Mizoguchi, Tatsuya; Shinohara, Akio; Kouguchi, Hirokazu; Sunden, Yuji; Otsuka-Kanazawa, Saori; Ali Elewa, Yaser Hosny; Koshimoto, Chihiro; Nagasaki, Ken-Ichi; Kon, Yasuhiro

    2018-06-01

    Pharyngeal pouches in mammals develop into specific derivatives. If the differentiation of the pharyngeal pouches is anomalous, their remnants can result in cysts, sinuses, and fistulae in the differentiated organs or around the neck. In the present study, we found several pharyngeal pouch remnants, such as cystic structures in thymus and parathyroid gland and fossulae extended from the piriform fossa, in the inbred cotton rats maintained at Hokkaido Institute of Public Health (HIS/Hiph) and University of Miyazaki (HIS/Mz). In HIS/Hiph, the fossulae extended from the apex of the piriform fossa into the thyroid glands and were lined with stratified squamous and cuboidal epithelium. Calcitonin-positive C-cells were present within their epithelium in HIS/Hiph. In contrast, the fossulae of HIS/Mz ran outside the thyroid glands toward the parathyroid glands; they were lined with columnar ciliated epithelium and a few goblet cells, but had no C-cells, which was consistent with the cystic structures in the thymus and the parathyroid gland. These results indicated that the fossulae were a remnant of the ultimobranchial body in HIS/Hiph and of the thymopharyngeal duct in HIS/Mz. Thus, the fossulae of the piriform fossa resembled the piriform sinus fistula in human. In conclusion, cotton rats frequently possessed pharyngeal pouch remnants, including the piriform sinus fistula, and therefore, might serve as a novel model to elucidate the mechanisms of pharyngeal pouch development.

  20. Energy Dependence of Synchrotron X-Ray Rims in Tycho's Supernova Remnant

    NASA Technical Reports Server (NTRS)

    Tran, Aaron; Williams, Brian J.; Petre, Robert; Ressler, Sean M.; Reynolds, Stephen P.

    2015-01-01

    Several young supernova remnants exhibit thin X-ray bright rims of synchrotron radiation at their forward shocks. Thin rims require strong magnetic field amplification beyond simple shock compression if rim widths are only limited by electron energy losses. But, magnetic field damping behind the shock could produce similarly thin rims with less extreme field amplification. Variation of rim width with energy may thus discriminate between competing influences on rim widths. We measured rim widths around Tycho's supernova remnant in 5 energy bands using an archival 750 ks Chandra observation. Rims narrow with increasing energy and are well described by either loss-limited or damped scenarios, so X-ray rim width-energy dependence does not uniquely specify a model. But, radio counterparts to thin rims are not loss-limited and better reflect magnetic field structure. Joint radio and X-ray modeling favors magnetic damping in Tycho's SNR with damping lengths approximately 1-5% of remnant radius and magnetic field strengths approximately 50-400 micron G assuming Bohm diffusion. X-ray rim widths are approximately 1% of remnant radius, somewhat smaller than inferred damping lengths. Electron energy losses are important in all models of X-ray rims, suggesting that the distinction between loss-limited and damped models is blurred in soft X-rays. All loss-limited and damping models require magnetic fields approximately greater than 20 micron G, arming the necessity of magnetic field amplification beyond simple compression.

  1. [Interpretation on Chinese surgeons' consensus opinion for the definition of gastric stump cancer (version 2018)].

    PubMed

    Gao, Zhidong; Jiang, Kewei; Ye, Yingjiang; Wang, Shan

    2018-05-25

    Gastric stump cancer(GSC) is defined as newly developed remnant stomach cancer following gastrectomy. This definition initially referred to carcinoma detected in the remnant stomach more than 5 years after the primary surgery for a benign disease. Subsequently, this timeframe was extended to 10 years after the primary surgery for a malignant disease. Recently, the concept of "carcinoma in the remnant stomach(CRS)" proposed by the Japanese Gastric Cancer Association was introduced in China. The new definition encompasses all carcinomas arising in the remnant stomach following gastrectomy, irrespective of the histology of the primary lesion, extent of resection, or reconstruction method. It includes all carcinoma types that have developed in the remnant stomach, such as newly developed cancer, recurrent cancer, remaining cancer, and multiple cancers. Considering the current diagnosis and treatment status of gastric cancer in China, if CRS is to be used as a direct equivalent to GSC in clinical practice, confusion may arise concerning disease identification and diagnosis. Following several discussion rounds, a meta-analysis of the literatures at home and abroad, and a multicenter national retrospective study with a large sample population, the "Chinese surgeons' consensus opinion for the definition of gastric stump cancer (version 2018)" was completed. By reviewing the detailed evidence-based medicine supporting the consensus document, this paper aims to assist clinical diagnosis and enhance future academic exchange.

  2. A new iphiculid crab (Crustacea, Brachyura, Leucosioidea) from the Middle Miocene of Austria, with notes on palaeobiogeography of Iphiculus

    PubMed Central

    Hyžný, Matúš; Gross, Martin

    2017-01-01

    A new fossil species of the iphiculid genus Iphiculus Adams & White, 1849, (Crustacea, Brachyura) is described on the basis of three specimens from the Middle Miocene Florian Beds of Styria, Austria. Iphiculus eliasi sp. nov. constitutes the first European record of the genus. This occurrence represents the oldest record of Iphiculus, having implications for the palaeobiogeographic history of the family Iphiculidae. It is suggested that Iphiculus may have originated in the Western Tethys and migrated subsequently into the Indo-West Pacific. Alternatively, its current geographic restriction to the Indo-West Pacific can be a remnant of an ancient broader geographic distribution. PMID:27811673

  3. Planetary Magnetism

    NASA Technical Reports Server (NTRS)

    Connerney, J. E. P.

    2007-01-01

    The chapter on Planetary Magnetism by Connerney describes the magnetic fields of the planets, from Mercury to Neptune, including the large satellites (Moon, Ganymede) that have or once had active dynamos. The chapter describes the spacecraft missions and observations that, along with select remote observations, form the basis of our knowledge of planetary magnetic fields. Connerney describes the methods of analysis used to characterize planetary magnetic fields, and the models used to represent the main field (due to dynamo action in the planet's interior) and/or remnant magnetic fields locked in the planet's crust, where appropriate. These observations provide valuable insights into dynamo generation of magnetic fields, the structure and composition of planetary interiors, and the evolution of planets.

  4. The positive binding energy envelopes of low-mass helium stars

    NASA Astrophysics Data System (ADS)

    Hall, Philip D.; Jeffery, C. Simon

    2018-04-01

    It has been hypothesized that stellar envelopes with positive binding energy may be ejected if the release of recombination energy can be triggered and the calculation of binding energy includes this contribution. The implications of this hypothesis for the evolution of normal hydrogen-rich stars have been investigated, but the implications for helium stars - which may represent mass-transfer or merger remnants in binary star systems - have not. Making a set of model helium stars, we find that those with masses between 0.9 and 2.4 M⊙ evolve to configurations with positive binding energy envelopes. We discuss consequences of the ejection hypothesis for such stars, and possible observational tests of these predictions.

  5. Use of a Marine Vertebrate, the Flounder, in the Physiology Teaching Laboratory

    ERIC Educational Resources Information Center

    Bruce, David S.; Linden, Donald G.

    1973-01-01

    Describes two experiments in physiology using a readily available marine vertebrate, the flounder. Representative results are presented from experiments which measure the effect of excess potassium on the flounder EKG, and the effect of temperature on heart rate of the starry flounder. (JR)

  6. Bacteria in the Tatahouine meteorite: nanometric-scale life in rocks.

    PubMed

    Gillet, P h; Barrat, J A; Heulin, T h; Achouak, W; Lesourd, M; Guyot, F; Benzerara, K

    2000-02-15

    We present a study of the textural signature of terrestrial weathering and related biological activity in the Tatahouine meteorite. Scanning and transmission electron microscopy images obtained on the weathered samples of the Tatahouine meteorite and surrounding soil show two types of bacteria-like forms lying on mineral surfaces: (1) rod-shaped forms (RSF) about 70-80 nm wide and ranging from 100 nm to 600 nm in length; (2) ovoid forms (OVF) with diameters between 70 and 300 nm. They look like single cells surrounded by a cell wall. Only Na, K, C, O and N with traces of P and S are observed in the bulk of these objects. The chemical analyses and electron diffraction patterns confirm that the RSF and OVF cannot be magnetite or other iron oxides, iron hydroxides, silicates or carbonates. The sizes of the RSF and OVF are below those commonly observed for bacteria but are very similar to some bacteria-like forms described in the Martian meteorite ALH84001. All the previous observations strongly suggest that they are bacteria or their remnants. This conclusion is further supported by microbiological experiments in which pleomorphic bacteria with morphology similar to the OVF and RSF objects are obtained from biological culture of the soil surrounding the meteorite pieces. The present results show that bacteriomorphs of diameter less than 100 nm may in fact represent real bacteria or their remnants.

  7. Genetic variation and structure in remnant population of critically endangered Melicope zahlbruckneri

    USGS Publications Warehouse

    Raji, J. A.; Atkinson, Carter T.

    2016-01-01

    The distribution and amount of genetic variation within and between populations of plant species are important for their adaptability to future habitat changes and also critical for their restoration and overall management. This study was initiated to assess the genetic status of the remnant population of Melicope zahlbruckneri–a critically endangered species in Hawaii, and determine the extent of genetic variation and diversity in order to propose valuable conservation approaches. Estimated genetic structure of individuals based on molecular marker allele frequencies identified genetic groups with low overall differentiation but identified the most genetically diverse individuals within the population. Analysis of Amplified Fragment Length Polymorphic (AFLP) marker loci in the population based on Bayesian model and multivariate statistics classified the population into four subgroups. We inferred a mixed species population structure based on Bayesian clustering and frequency of unique alleles. The percentage of Polymorphic Fragment (PPF) ranged from 18.8 to 64.6% for all marker loci with an average of 54.9% within the population. Inclusion of all surviving M. zahlbruckneri trees in future restorative planting at new sites are suggested, and approaches for longer term maintenance of genetic variability are discussed. To our knowledge, this study represents the first report of molecular genetic analysis of the remaining population of M. zahlbruckneri and also illustrates the importance of genetic variability for conservation of a small endangered population.

  8. Tori sequences as remnants of multiple accreting periods of Kerr SMBHs

    NASA Astrophysics Data System (ADS)

    Pugliese, D.; Stuchlík, Z.

    2018-03-01

    Super-massive black holes (SMBHs) hosted in active galactic nuclei (AGNs) can be characterized by multi-accreting periods as the attractors interact with the environment during their life-time. These multi-accretion episodes should leave traces in the matter orbiting the attractor. Counterrotating and even misaligned structures orbiting around the SMBHs would be consequences of these episodes. Our task in this work is to consider situations where such accretions occur and to trace their remnants represented by several toroidal accreting fluids, corotating or counterrotating relative to the central Kerr attractor, and created in various regimes during the evolution of matter configurations around SMBHs. We focus particularly on the emergence of matter instabilities, i.e., tori collisions, accretion onto the central Kerr black hole, or creation of jet-like structures (proto-jets). Each orbiting configuration is governed by the general relativistic hydrodynamic Boyer condition of equilibrium configurations of rotating perfect fluid. We prove that sequences of configurations and hot points, where an instability occurs, characterize the Kerr SMBHs, depending mainly on their spin-mass ratios. The occurrence of tori accretion or collision are strongly constrained by the fluid rotation with respect to the central black hole and the relative rotation with respect to each other. Our investigation provides characteristic of attractors where traces of multi-accreting episodes can be found and observed.

  9. Thermal and Nonthermal X-ray Emission from the Forward Shock in Tycho's Supernova Remnant

    NASA Technical Reports Server (NTRS)

    Hwang, Una; Decourchelle, Anne; Holt, Stephen S.; Petre, Robert; White, Nicholas E. (Technical Monitor)

    2002-01-01

    We present Chandra CCD images of Tycho's supernova remnant that delineate its outer shock, seen as a thin, smooth rim along the straight northeastern edge and most of the circular western half. The images also show that the Si and S ejecta are highly clumpy, and have reached the forward shock at numerous locations. Most of the X-ray spectra that we examine along the rim show line emission from Si and S, which in some cases must come from ejecta; the continuum is well represented by either thermal or nonthermal models. In the case that the continuum is assumed to be thermal, the temperatures at the rim are all similar at about 2 keV, and the ionization ages are very low because of the overall weakness of the line emission. Assuming shock velocities inferred from radio and X-ray expansion measurements, these temperatures are substantially below those expected for equilibration of the electron and ion temperatures; electron to mean temperature ratios of approximately less than 0.1 - 0.2 indicate at most modest collisionless heating of the electrons at the shock. The nonthermal contribution to these spectra may be important, however, and may account for as many as half of the counts in the 4-6 keV energy range, based on an extrapolation of the hard X-ray spectrum above 10 keV.

  10. The Genome of Selaginella: A Remnant of an Ancient Vascular Plant Lineage (JGI Seventh Annual User Meeting, 2012: Genomics of Energy and Environment)

    ScienceCinema

    Banks, Jody

    2018-02-12

    Jody Banks from Purdue University on "The Genome of Selaginella, a Remnant of an Ancient Vascular Plant Lineage" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, Calif.

  11. 14. DETAIL OF REMNANTS OF WASTE GATE FRAME OF SPILLWAY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. DETAIL OF REMNANTS OF WASTE GATE FRAME OF SPILLWAY AND INLET OF PIPE CULVERT UNDER NORTHERLY END OF SPILLWAY APRON; VIEW TO WEST. - Blackstone Canal Millbury Segment, Beginning northwest of State Route 146 & McCracken Road, running along west side of Route 146, Millbury, Worcester County, MA

  12. Rapid re-brightening of the red nova V4332 Sgr remnant

    NASA Astrophysics Data System (ADS)

    Goranskij, V. P.; Zharova, A. V.; Barsukova, E. A.; Valeev, A. F.

    2018-06-01

    V4332 Sgr is a luminous red nova exploded in 1994. We perform CCD BVRcIc photometry of its remnant since 2003, and medium resolution spectroscopy since 2005 using Russian 6 m telescope BTA, SAO 1 m Zeiss telescope and smaller telescopes of SAI Crimean Station.

  13. 6. OLD AND NEW TIOGA ROAD. NOTE REMNANTS OF OLD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. OLD AND NEW TIOGA ROAD. NOTE REMNANTS OF OLD ROAD ON LEFT. NOTE ROAD CUT ON CANYON WALL IN CENTER REAR. LOOKING NNE. GIS: N-37 56 19.5 / W-119 13 53.3 - Tioga Road, Between Crane Flat & Tioga Pass, Yosemite Village, Mariposa County, CA

  14. Do remnant old-growth trees accelerate rates of succession in mature Douglas-fir forests?

    Treesearch

    William S. Keeton; Jerry F. Franklin

    2005-01-01

    Biological legacies left by natural disturbances provide ecological functions throughout forest stand development, but their influences on processes of ecological succession are not completely understood. We investigated the successional role of one type of biological legacy: remnant old-growth trees persisting in mature Pseudotsuga menziesii (...

  15. Brassica vegetables as a green manure to control Escherichia coli O157:H12 in soil

    USDA-ARS?s Scientific Manuscript database

    Plant remnants tilled over in soil after harvest of Brassica crops may possess antimicrobial from exudates secreted in soil following residual incorporation. We investigated the role of broccoli remnants tilled over after harvest for reducing enteric pathogens in soil. The glucosinolate-hydrolyzed c...

  16. Brassica vegetables as a green manure to control Escherichia coli O157:H12 in soil

    USDA-ARS?s Scientific Manuscript database

    Plant remnants tilled over in soil after harvest of Brassica crops may possess antimicrobial from exudates secreted in soil following residual incorporation (till over). We investigated the role of broccoli remnants tilled over after harvest for reducing enteric pathogens in soil. The glucosinolate-...

  17. Physiological Response to Reward and Extinction Predicts Alcohol, Marijuana, and Cigarette Use Two Years Later

    PubMed Central

    Derefinko, Karen J.; Eisenlohr-Moul, Tory A.; Peters, Jessica R.; Roberts, Walter; Walsh, Erin C.; Milich, Richard; Lynam, Donald R.

    2017-01-01

    Background Physiological responses to reward and extinction are believed to represent the Behavioral Activation System (BAS) and Behavioral Inhibition System (BIS) constructs of Reinforcement Sensitivity Theory and underlie externalizing behaviors, including substance use. However, little research has examined these relations directly. Methods We assessed individuals’ cardiac pre-ejection periods (PEP) and electrodermal responses (EDR) during reward and extinction trials through the “Number Elimination Game” paradigm. Responses represented BAS and BIS, respectively. We then examined whether these responses provided incremental utility in the prediction of future alcohol, marijuana, and cigarette use. Results Zero-inflated Poisson (ZIP) regression models were used to examine the predictive utility of physiological BAS and BIS responses above and beyond previous substance use. Physiological responses accounted for incremental variance over previous use. Low BAS responses during reward predicted frequency of alcohol use at year 3. Low BAS responses during reward and extinction and high BIS responses during extinction predicted frequency of marijuana use at year 3. For cigarette use, low BAS response during extinction predicted use at year 3. Conclusions These findings suggest that the constructs of Reinforcement Sensitivity Theory, as assessed through physiology, contribute to the longitudinal maintenance of substance use. PMID:27306728

  18. Physiological Feedback Method and System

    NASA Technical Reports Server (NTRS)

    Pope, Alan T. (Inventor); Severance, Kurt E. (Inventor)

    2002-01-01

    A method and system provide physiological feedback for a patient and/or physician. At least one physiological effect experienced by a body part of a patient is measured noninvasively. A three-dimensional graphics model serving as an analogous representation of the body part is altered in accordance with the measurements. A binocular image signal representative of the three-dimensional graphics model so-altered is displayed for the patient and/or physician in a virtual reality environment.

  19. NASA Scientists Witness a Supernova Cosmic Rite of Passage

    NASA Astrophysics Data System (ADS)

    2005-11-01

    Scientists using NASA's Chandra X-ray Observatory have witnessed a cosmic rite of passage, the transition from a supernova to a supernova remnant, a process that has never been seen in much detail until now, leaving it poorly defined. A supernova is a massive star explosion; the remnant is the beautiful glowing shell that evolves afterwards. When does a supernova become supernova remnant? When does the shell appear and what powers its radiant glow? A science team led by Dr. Stefan Immler of NASA's Goddard Space Flight Center, Greenbelt, Md., has taken a fresh look at a supernova that exploded in 1970, called SN 1970G, just off the handle of the Big Dipper. This is the oldest supernova ever seen by X-ray telescopes. Chandra X-ray Image of SN 1970G Chandra X-ray Image of SN 1970G "Some astronomers have thought there's a moment when the supernova remnant magically turns on years after the supernova itself has faded away, when the shock wave of the explosion finally hits and lights up the interstellar medium," said Immler. "By contrast, our results show that a new supernova quickly and seamlessly evolves into a supernova remnant. The star's own debris, and not the interstellar medium gas, fuels the remnant." These results appear in The Astrophysical Journal, co-authored by Dr. Kip Kuntz, also of Goddard. They support previous Chandra observations of SN 1987A by Dr. Sangwook Park of Penn State. Using new data from Chandra and archived data from the European-led ROSAT and XMM-Newton observatories, Immler and Kuntz pieced together how SN 1970G evolved over the years. They found telltale signs of a supernova remnant - bright X-ray light - yet no evidence of interstellar gas, even across a distance around the site of the explosion 35 times larger than our solar system. Instead, the material that is heated by the supernova shock to glow in X-ray light, what we call the remnant, is from the stellar wind of the star itself and not distant gas in the interstellar medium. This wind, comprising energetic ions, was shed by the progenitor star thousands to million of years before the explosion. If this were from the interstellar medium, it would be much denser than this stellar wind. NOAO Optical Image of SN 1970G NOAO Optical Image of SN 1970G Immler and Kuntz next studied the density profiles of all other supernovae that have been detected over the past two decades. Sure enough, the low-density circumstellar matter from the stellar wind was the source of X-rays, not the interstellar medium. Immler said that historical supernova remnants such as Cassiopeia A, which exploded some 320 years ago, also show no signs of activity from the interstellar medium. This is more than just a name game, more than hypothetically changing SN 1970G to SNR 1970G. "We have to rethink this notion that a shock wave from the supernova crashes into the interstellar medium to create a supernova remnant," said Immler. "The luminous supernova remnants that we see can be created without the need of a dense interstellar medium. In fact, our study showed that all supernovae detected in X-rays over the past 25 years live in a low-density environment." SN 1970G is located in the galaxy M101, also called the Pinwheel Galaxy, a stunning spiral galaxy about 22 million light years away in the constellation Ursa Major, home of the Big Dipper. Although the galaxy itself is visible from dark skies with binoculars, telescopes cannot resolve much structure in SN 1970G, unlike for supernova remnants in our Milky Way galaxy. Discovered with an optical telescope in 1970, SN 1970G was not seen with X-ray telescopes until the 1990s. Immler's work at NASA Goddard is supported through the Universities Space Research Association. Kuntz is supported through University of Maryland, Baltimore County. NASA's Marshall Space Flight Center in Huntsville, Ala., manages the Chandra program for the Agency's Science Mission Directorate. The Smithsonian Astrophysical Observatory controls science and flight operations from the Chandra X-ray Center in Cambridge, Mass. Additional information and images are available at: http://chandra.harvard.edu and http://chandra.nasa.gov

  20. LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis

    PubMed Central

    Zhou, Li; Plattner, Florian; Liu, Mingxia; Parks, John S; Hammer, Robert E; Boucher, Philippe; Tsai, Shirling

    2017-01-01

    Low-density lipoprotein receptor-related protein 1 (LRP1) is a multifunctional cell surface receptor with diverse physiological roles, ranging from cellular uptake of lipoproteins and other cargo by endocytosis to sensor of the extracellular environment and integrator of a wide range of signaling mechanisms. As a chylomicron remnant receptor, LRP1 controls systemic lipid metabolism in concert with the LDL receptor in the liver, whereas in smooth muscle cells (SMC) LRP1 functions as a co-receptor for TGFβ and PDGFRβ in reverse cholesterol transport and the maintenance of vascular wall integrity. Here we used a knockin mouse model to uncover a novel atheroprotective role for LRP1 in macrophages where tyrosine phosphorylation of an NPxY motif in its intracellular domain initiates a signaling cascade along an LRP1/SHC1/PI3K/AKT/PPARγ/LXR axis to regulate and integrate cellular cholesterol homeostasis through the expression of the major cholesterol exporter ABCA1 with apoptotic cell removal and inflammatory responses. PMID:29144234

  1. X-Rays form the Vela-Puppis Complex

    NASA Technical Reports Server (NTRS)

    Bunner, A. N.

    1971-01-01

    A review of X-ray observations in the vicinity of the Gum nebula is presented. There is little doubt that the filamentary nebula Stromlo 16, the radio source Vela X, and the extended X-ray object Vel XR-2 are indications of the same, relatively nearby, supernova remnant. X-ray absorption measurements are consistent with a distance of 500 + or - 100 pc. The observed X-ray spectra have not yet distinguished between thermal bremsstrahlung and synchrotron radiation as the source mechanism. A search for low energy X-ray emission lines, both within the 5 deg diameter remnant and in the larger Gum nebula, may provide an important test for models of supernova remnant evolution.

  2. Investigating the galactic Supernova Remnant Kes 78 with XMM-Newton

    NASA Astrophysics Data System (ADS)

    Miceli, M.; Bamba, A.; Orlando, S.; Bocchino, F.

    2016-06-01

    The galactic supernova remnant Kes 78 is associated with a HESS gamma-ray source and its X-ray emission has been recently revealed by Suzaku observations which have found indications for a hard X-ray component in the spectra. We analyzed an XMM-Newton EPIC observation of Kes 78 and studied the spatial distribution of the physical and chemical properties of the X-ray emitting plasma. The EPIC data unveiled a very complex morphology for the soft X-ray emission. We performed image analysis and spatially resolved spectral analysis finding indications for the interaction of the remnant with a local molecular cloud. Finally, we investigated the origin of the hard X-ray emitting component.

  3. Investigating the Galactic supernova remnant Kes 78 with XMM-Newton

    NASA Astrophysics Data System (ADS)

    Miceli, Marco; Bamba, Aya; Orlando, Salvatore; Bocchino, Fabrizio

    2016-06-01

    The galactic supernova remnant Kes 78 is associated with a HESS gamma-ray source and its X-ray emission has been recently revealed by Suzaku observations which have found indications for a hard X-ray component in the spectra. We analyzed an XMM-Newton EPIC observation of Kes 78 and studied the spatial distribution of the physical and chemical properties of the X-ray emitting plasma. The EPIC data unveiled a very complex morphology for the soft X-ray emission. We performed image analysis and spatially resolved spectral analysis finding indications for the interaction of the remnant with a local molecular cloud. Finally, we investigated the origin of the hard X-ray emitting component.

  4. Onion-shell model for cosmic ray electrons and radio synchrotron emission in supernova remnants

    NASA Technical Reports Server (NTRS)

    Beck, R.; Drury, L. O.; Voelk, H. J.; Bogdan, T. J.

    1985-01-01

    The spectrum of cosmic ray electrons, accelerated in the shock front of a supernova remnant (SNR), is calculated in the test-particle approximation using an onion-shell model. Particle diffusion within the evolving remnant is explicity taken into account. The particle spectrum becomes steeper with increasing radius as well as SNR age. Simple models of the magnetic field distribution allow a prediction of the intensity and spectrum of radio synchrotron emission and their radial variation. The agreement with existing observations is satisfactory in several SNR's but fails in other cases. Radiative cooling may be an important effect, especially in SNR's exploding in a dense interstellar medium.

  5. Cyanosis and Stroke due to Functional Cor Triatriatum Dexter in a Neonate.

    PubMed

    León, Rachel L; Zaban, Nicholas B; Schamberger, Marcus S; Ho, Chang Y; Mietzsch, Ulrike

    2018-01-01

    Small remnants of the right valve of the sinus venosus are commonly found in adults, but the incidence and risk associated with these embryonic remnants in neonates are not well studied. The following report describes a cyanotic neonate with a large Eustachian valve remnant creating a functional cor triatriatum dexter who was initially diagnosed with persistent pulmonary hypertension of the newborn. The cyanosis in this infant improved over the first postnatal week with conservative management, but she suffered multifocal subcortical stroke, likely related to her intracardiac shunt. The clinical presentation and questions regarding long-term management of this rare diagnosis are explored. © 2018 S. Karger AG, Basel.

  6. Influence of urbanization on the original vegetation cover in urban river basin: case study in Campinas/SP, Brazil

    NASA Astrophysics Data System (ADS)

    Leite Silva, Alessandra; Márcia Longo, Regina

    2017-04-01

    ABSTRACT: In most Brazilian municipalities, urban development was not based on adequate planning; one of the consequences was the reduction of the original vegetation, limiting the forest formations to scarce and isolated fragments. In Campinas, São Paulo, Brazil, the vegetation fragmentation was mainly related to the expeditions and to the cycles of sugar cane and coffee. In this way, the present study aims to identify, quantify and evaluate the remaining arboreal vegetation spatial distribution in the Anhumas River Basin - Campinas/SP, Brazil. This study was developed with the aid of GIS software and field visits in order to construct a diagnosis of these areas and subsidize future actions required and to discuss the influence of urbanization on the original vegetation cover. The area was initially occupied by the Atlantic Forest (semi-deciduous forest) and drains one of the oldest urban occupation areas in the municipality; according to researchers, based on the water and geomorphological conditions of the basin, it can be subdivided into high, medium and low course. With a total area of 156,514 km2, only 16.74% are classified as green areas; where just 1.07% and 6.17% of total area represents forests and reforestation areas, respectively. The remaining green areas consists of: wetlands close to water bodies, but with no presence of trees and shrubs (area of 0.12% of the basin); urban green space, including parks and squares (2.19%); and natural field, constituted by natural non-arboreous vegetation (7.18%). In a scenario like this, a characteristic situation is the forest fragmentation; this process results in native vegetation remnants, isolated and more susceptible to external interference, coming from, for example, the proximity to agricultural areas or others land uses. The ecological knowledge of the remnants and their correct management can not only make it possible to diagnose current problems and to estimate future influences, but also to point out the necessary changes to maintain the environmental balance. In the Anhumas River Basin were identified 128 forest fragments, including remnants of natural vegetation and also from successful reforestation. Most of them, 112 fragments, have an area between 1.0 and 20.0 ha; There are only 7 fragments with area lower than 1.0 ha and 9 fragments greather than 20 ha. Furthermore, most of them are located in the lower course, covering an area of 652.23 ha, 4.17% in relation to the total area of the basin; in the middle course are 216.61 ha occupied by fragments, encompassing 1.38% of the total area; and finally in the upper course, the most urbanized region of the basin, there are just 133.26 ha of fragments, representing only 0.85% of area. One may observe that the number of the forest fragments and their areas are getting smaller as they approach the urban perimeter; this fact shows a direct link between urbanization and the significant loss of vegetation cover, resulting in negative effects on the life quality and urban environmental balance, such as the reduction of soil infiltration, the water runoff increased, the urban temperature increase, urban heat island, floods and other associated problems. These analyzes, therefore, contribute to help the environmental management in an appropriate way, considering the demands and potentialities of the region. Key words: River basin, forest remnants, environmental quality.

  7. Species composition and structure of regenerated and remnant forest patches within an urban landscape

    Treesearch

    Wayne C. Zipperer

    2002-01-01

    Regenerated and remnant forest patches were inventoried in Syracuse, New York, USA to determine differences in structure, species composition, human disturbances, and landscape context. Patches had similar mean stem diameter, total stem density, and total basal areas, but differed with respect to diameter distribution, disturbance regime, landscape context, and...

  8. Bat use of remnant old-growth redwood stands

    Treesearch

    William J. Zielinski; Steven T. Gellman

    1999-01-01

    Most of the old-growth redwood (Sequoia sempervirens) in Calfornia has been cut; regenerating forests will probably never resemble those that were harvested, and what old growth remains on private land occurs in small, isolated remnant patches. The landscapes in which these stands occur differ so markedly from their original condition that their...

  9. Remnant fire disturbed montane longleaf pine forest in west central georgia

    Treesearch

    Robert Carter; Andrew J. Londo

    2006-01-01

    Fire disturbed ecosystems are characteristic of the Southeastern Coastal Plain of the United States. Less well known are fire disturbed mountainous regions of the Piedmont and Appalachian region that support longleaf pine (Pinus palustris P. Mill.) ecosystems. The Pine Mountain Range in the Piedmont of west central Georgia has remnant longleaf pine...

  10. Search for Remnant Water Ice from Past Glacial Climates on Mars: The Mars Odyssey Neutron Spectrometer

    NASA Astrophysics Data System (ADS)

    Feldman, W. C.; Prettyman, T. H.; Maurice, S.; Lawrence, D. J.; Pathare, A.; Milliken, R. E.; Travis, B. J.

    2011-03-01

    We find at least three likely target locations of presently existing deposits of buried "bulk" water ice that may be remnants of multiple episodes of dirty ice precipitation events at low to mid-martian latitudes driven by climate changes during the last 1 to 10 Ma.

  11. Do adhesive systems leave resin coats on the surfaces of the metal matrix bands? An adhesive remnant characterization.

    PubMed

    Arhun, Neslihan; Cehreli, Sevi Burcak

    2013-01-01

    Reestablishing proximal contacts with composite resins may prove challenging since the applied adhesives may lead to resin coating that produces additional thickness. The aim of this study was to investigate the surface of metal matrix bands after application of adhesive systems and blowing or wiping off the adhesive before polymerization. Seventeen groups of matrix bands were prepared. The remnant particles were characterized by energy dispersive spectrum and scanning electron microscopy. Total etch and two-step self-etch adhesives did not leave any resin residues by wiping and blowing off. All-in-one adhesive revealed resin residues despite wiping off. Prime and Bond NT did not leave any remnant with compomer. Clinicians must be made aware of the consequences of possible adhesive remnants on matrix bands that may lead to a defective definitive restoration. The adhesive resin used for Class II restorations may leave resin coats on metal matrix bands after polymerization, resulting in additional thickness on the metal matrix bands and poor quality of the proximal surface of the definitive restoration when the adhesive system is incorporated in the restoration.

  12. A broadband study of the emission from the composite supernova remnant MSH 11-62

    DOE PAGES

    Slane, Patrick; Hughes, John P.; Temim, Tea; ...

    2012-03-30

    MSH 11-62 (G291.0-0.1) is a composite supernova remnant for which radio and X-ray observations have identified the remnant shell as well as its central pulsar wind nebula. Our observations suggest a relatively young system expanding into a low-density region. We present a study of MSH 11-62 using observations with the Chandra, XMM -Newton, and Fermi observatories, along with radio observations from the Australia Telescope Compact Array. We also identify a compact X-ray source that appears to be the putative pulsar that powers the nebula, and show that the X-ray spectrum of the nebula bears the signature of synchrotron losses asmore » particles diffuse into the outer nebula. Using data from the Fermi Large Area Telescope, we identify γ-ray emission originating from MSH 11-62. Furthermore, with density constraints from the new X-ray measurements of the remnant, we model the evolution of the composite system in order to constrain the properties of the underlying pulsar and the origin of the γ-ray emission.« less

  13. Fermi-Lat and WMAP Observations of the Puppis a Supernova Remnant

    NASA Technical Reports Server (NTRS)

    Hewitt, John William; Grondin, M. H.; Lemoine-Goumard, M.; Reposeur, T.; Ballet, J.; Tanaka, T.

    2012-01-01

    We report the detection of GeV gamma-ray emission from the supernova remnant Puppis A with the Fermi Gamma-Ray Space Telescope. Puppis A is among the faintest supernova remnants yet detected at GeV energies, with a luminosity of only 2.7×10(exp 34) (D/2.2 kpc)(exp 2) erg s(exp -1) between 1 and 100 GeV. The gamma-ray emission from the remnant is spatially extended, with a morphology matching that of the radio and X-ray emission, and is well described by a simple power law with an index of 2.1. We attempt to model the broadband spectral energy distribution, from radio to gamma-rays, using standard nonthermal emission mechanisms. To constrain the relativistic electron population we use 7 years of WMAP data to extend the radio spectrum up to 93 GHz. Both leptonic and hadronic dominated models can reproduce the nonthermal spectral energy distribution, requiring a total content of cosmic ray (CR) electrons and protons accelerated in Puppis A of at least WCR is approx. (1 - 5)×10 (exp 49) erg.

  14. Comparison of the effects of dietary saturated, mono-unsaturated and polyunsaturated fatty acids on very-low-density lipoprotein secretion when delivered to hepatocytes in chylomicron remnant-like particles.

    PubMed

    Lopez-Soldado, I; Avella, M; Botham, K M

    2007-06-01

    The effect of chylomicron remnant-like particles (CRLPs) enriched in saturated, mono-unsaturated or n-6 polyunsaturated fatty acids (derived from palm, olive or corn oil, respectively) on the secretion of VLDL (very-low-density lipoprotein) by rat hepatocytes in culture was investigated. CRLPs were incubated with cultured hepatocytes for 5 h. The medium was then removed and the secretion of cholesterol and triacylglycerol (TAG) into the whole medium during the following 16 h was determined. After exposure of the cells to olive oil as compared with corn and palm oil CRLPs, secretion of TAG into the medium was decreased. The TAG content of the cells was also lower in experiments with olive oil as compared with corn oil CRLPs. The levels of apoB48 (apolipoprotein B48) found in the medium remained unchanged after the exposure of the cells to the different types of remnants. These findings indicate that the type of fat in the diet directly affects VLDL lipid secretion on delivery to the liver in chylomicron remnants.

  15. A Broadband Study of the Emission from the Composite Supernova Remnant MSH 11-62

    NASA Technical Reports Server (NTRS)

    Slane, Patrick; Hughes, John P.; Temim, Tea; Rousseau, Romain; Castro, Daniel; Foight, Dillon; Gaensler, B. M.; Funk, Stefan; Lemoine-Goumard, Marianne; Gelfand, Joseph D.; hide

    2012-01-01

    MSH 11-62 (G29U)-Q.1) is a composite supernova remnant for which radio and X-ray observations have identified the remnant shell as well as its central pulsar wind nebula. The observations suggest a relatively young system expanding into a low-density region. Here, we present a study of MSH ll-62 using observations with the Chandra, XMM-Newton, and Fermi observatories, along with radio observations from the Australia Telescope Compact Array. We identify a compact X-ray source that appears to be the putative pulsar that powers the nebula, and show that the X-ray spectrum of the nebula bears the signature of synchrotron losses as particles diffuse into the outer nebula. Using data from the Fermi Large Area Telescope, we identify gamma-ray emission originating from MSH 11-62. With density constraints from the new X-ray measurements of the remnant, we model the evolution of the composite system in order to constrain the properties of the underlying pulsar and the origin of the gamma-ray emission.

  16. High Resolution X-Ray Spectroscopy and Imaging of Supernova Remnant N132D

    NASA Technical Reports Server (NTRS)

    Behar, Ehud; Rasmussen, Andrew; Griffiths, R. Gareth; Dennerl, Konrad; Audard, Marc; Aschenbach, Bernd

    2000-01-01

    The observation of the supernova remnant N132D by the scientific instruments on board the XMM-Newton satellite is presented. The X-rays from N132D are dispersed into a detailed line-rich spectrum using the Reflection Grating Spectrometers. Spectral lines of C, N, O, Ne, Mg, Si, S, and Fe are identified. Images of the remnant, in narrow wavelength bands, produced by the European Photon Imaging Cameras reveal a complex spatial structure of the ionic distribution. While K - shell Fe seems to originate near the centre, all of the other ions are observed along the shell. An emission excess of O(6+) over O(7+) is detected on the northeastern edge of the remnant. This can be a sign of hot ionising conditions, or it can reflect a relatively cool region. Spectral fitting of the CCD spectrum suggests high temperatures in this region, but a detailed analysis of the atomic processes involved in producing the O(6+) spectral lines leads to the conclusion that the intensities of these lines alone cannot provide a conclusive distinction between the two scenarios.

  17. Chandra Reveals Rich Oxygen Supply

    NASA Technical Reports Server (NTRS)

    2003-01-01

    This striking Chandra X-Ray Observatory image of supernova remnant SNR0103-72.6 reveals a nearly perfect ring about 150 light years in diameter surrounding a cloud of gas enriched in oxygen and shock-heated to millions of degrees Celsius. The ring marks the outer limits of a shock wave produced as material ejected in the supernova explosion collides with the interstellar gas. The size of the ring indicates that we see the supernova remnant as it was about 10,000 years after its progenitor star exploded. Located in the Small Magenellanic Cloud (SMC), SNR 0103-72.6 is about 190,000 light years from Earth. The x-rays take about 190,000 years to reach us from the SMC, so the supernova explosion occurred about 200,000 years ago, as measured on Earth. Scientists have know for years that oxygen and many other elements necessary for life are created in massive stars and dispersed in supernova explosions, but few remnants rich in these elements have been observed. This supernova remnant will hence become an important laboratory for studying how stars forge the elements necessary for life.

  18. Dust masses for SN 1980K, SN1993J and Cassiopeia A from red-blue emission line asymmetries

    NASA Astrophysics Data System (ADS)

    Bevan, Antonia; Barlow, M. J.; Milisavljevic, D.

    2017-03-01

    We present Monte Carlo line transfer models that investigate the effects of dust on the very late time emission line spectra of the core-collapse supernovae SN 1980K and SN 1993J and the young core collapse supernova remnant Cassiopeia A. Their blueshifted emission peaks, resulting from the removal by dust of redshifted photons emitted from the far sides of the remnants, and the presence of extended red emission wings are used to constrain dust compositions and radii and to determine the masses of dust in the remnants. We estimate dust masses of between 0.08 and 0.15 M⊙ for SN 1993J at year 16, 0.12 and 0.30 M⊙ for SN 1980K at year 30 and ∼1.1 M⊙ for Cas A at year ∼330. Our models for the strong oxygen forbidden lines of Cas A require the overall modelled profiles to be shifted to the red by between 700 and 1000 km s-1, consistent with previous estimates for the shift of the dynamical centroid of this remnant.

  19. X-Ray Measured Dynamics of Tycho's Supernova Remnant

    NASA Technical Reports Server (NTRS)

    Katsuda, Satoru; Petre, Robert; Hughes, John; Hwang, Una; Yamaguchi, Hiroya; Hayato, Asami; Mori, Koji; Tsunemi, Hiroshi

    2010-01-01

    We present X-ray proper-motion measurements of the forward shock and reverse-shocked ejecta in Tycho's supernova remnant, based on three sets of archival Chandra data taken in 2000, 2003, and 2007. We find that the proper motion of the edge of the remnant (i.e., the forward shock and protruding ejecta knots) varies from 0.''20 yr-1 (expansion index m = 0.33, where R = tm ) to 0.''40 yr-1 (m = 0.65) with azimuthal angle in 2000-2007 measurements, and 0.''14 yr-1 (m = 0.26) to 0.''40 yr-1 (m = 0.65) in 2003-2007 measurements. The azimuthal variation of the proper motion and the average expansion index of [approx]0.5 are consistent with those derived from radio observations. We also find proper motion and expansion index of the reverse-shocked ejecta to be 0.''21-0.''31 yr-1 and 0.43-0.64, respectively. From a comparison of the measured m-value with Type Ia supernova evolutionary models, we find a pre-shock ambient density around the remnant of [less, similar]0.2 cm-3.

  20. High-resolution radio and X-ray observations of the supernova remnant W28

    NASA Technical Reports Server (NTRS)

    Andrews, M. D.; Basart, J. P.; Lamb, R. C.; Becker, R. H.

    1983-01-01

    The present study has the objective to report the first high resolution radio and X-ray observations of the central part of the galactic supernova remnant, W28, taking into account the possible association of the remnant with the unidentified gamma-ray source, 2CG 006-00. This gamma-ray source is approximately two-thirds as bright as the Crab pulsar above 100 MeV, and has a somewhat flatter spectrum. Both the radio and X-ray observations reveal previously unknown aspects of W28 which support the possibility of W28 being a gamma-ray source. The radio data show a flat-spectrum, nonthermal component reminiscent of the Crab Nebula and Vela, both of which are confirmed gamma-ray sources. The X-ray observations reveal a compact source within W28, again suggestive of both the Crab and Vela. If the similarities among W28, the Crab Nebula, and the Vela remnant are valid, the gamma-ray source 2CG 00-00 should be studied for periodicity, the conclusive signature of a compact source of emission.

  1. Multilevel functional genomics data integration as a tool for understanding physiology: a network biology perspective.

    PubMed

    Davidsen, Peter K; Turan, Nil; Egginton, Stuart; Falciani, Francesco

    2016-02-01

    The overall aim of physiological research is to understand how living systems function in an integrative manner. Consequently, the discipline of physiology has since its infancy attempted to link multiple levels of biological organization. Increasingly this has involved mathematical and computational approaches, typically to model a small number of components spanning several levels of biological organization. With the advent of "omics" technologies, which can characterize the molecular state of a cell or tissue (intended as the level of expression and/or activity of its molecular components), the number of molecular components we can quantify has increased exponentially. Paradoxically, the unprecedented amount of experimental data has made it more difficult to derive conceptual models underlying essential mechanisms regulating mammalian physiology. We present an overview of state-of-the-art methods currently used to identifying biological networks underlying genomewide responses. These are based on a data-driven approach that relies on advanced computational methods designed to "learn" biology from observational data. In this review, we illustrate an application of these computational methodologies using a case study integrating an in vivo model representing the transcriptional state of hypoxic skeletal muscle with a clinical study representing muscle wasting in chronic obstructive pulmonary disease patients. The broader application of these approaches to modeling multiple levels of biological data in the context of modern physiology is discussed. Copyright © 2016 the American Physiological Society.

  2. A vocabulary of ancient peptides at the origin of folded proteins

    PubMed Central

    Alva, Vikram; Söding, Johannes; Lupas, Andrei N

    2015-01-01

    The seemingly limitless diversity of proteins in nature arose from only a few thousand domain prototypes, but the origin of these themselves has remained unclear. We are pursuing the hypothesis that they arose by fusion and accretion from an ancestral set of peptides active as co-factors in RNA-dependent replication and catalysis. Should this be true, contemporary domains may still contain vestiges of such peptides, which could be reconstructed by a comparative approach in the same way in which ancient vocabularies have been reconstructed by the comparative study of modern languages. To test this, we compared domains representative of known folds and identified 40 fragments whose similarity is indicative of common descent, yet which occur in domains currently not thought to be homologous. These fragments are widespread in the most ancient folds and enriched for iron-sulfur- and nucleic acid-binding. We propose that they represent the observable remnants of a primordial RNA-peptide world. DOI: http://dx.doi.org/10.7554/eLife.09410.001 PMID:26653858

  3. Constraining the number of compact remnants near Sgr A*

    NASA Astrophysics Data System (ADS)

    Deegan, Patrick; Nayakshin, Sergei

    2007-05-01

    Due to dynamical friction stellar mass black holes and neutron stars are expected to form high-density cusps in the inner parsec of our Galaxy. These compact remnants, expected to number around 20000, may be accreting cold dense gas present there, and give rise to potentially observable X-ray emission. Here we build a simple but detailed time-dependent model of such emission. The possibility that these accretion flows are radiatively inefficient is taken into account and brings in some uncertainty in the conclusions. Despite this uncertainty, we find that at least several X-ray sources of this nature should be detectable with Chandra at any one time. Turning this issue around, we also ask a question of what current observational constraints might be telling us about the total number of compact remnants. In our `best guess' model, a cusp of ~40000 remnants overpredicts the number of discrete sources and the total X-ray luminosity of the inner parsec, and is hence ruled out. In the most radiatively inefficient scenario that we consider, the radiative efficiency is set to be as small as ɛ = 10-5. In this rather unlikely scenario, a cusp of ~40000 black holes would be allowed by the data, but several individual sources should still be visible. Future observations of the distribution and orbits of the cold ionized gas in the inner parsec of our Galaxy will put tighter constraints on the cusp of compact remnants.

  4. Newly Formed Dust in the Core-Collapse Supernova Remnant E0102

    NASA Astrophysics Data System (ADS)

    Ludwig, Bethany; Sandstrom, Karin; Bolatto, Alberto

    2018-01-01

    The mechanism of interstellar dust formation is a matter of continuing debate. In the very early universe, some high redshift galaxies are observed to have a substantial amount of dust. This has led to the suggestion that core collapse supernovae must be the producers of much of the dust in the universe. However, most observed supernova remnants (SNRs) in the local universe have measured dust yields far below the necessary levels. Cassiopeia A and SN 1987A are exceptions--in these young remnants, Herschel Space Observatory observations found large quantities of newly-formed dust. In these two cases, the SNR is young enough that the reverse shock has not yet interacted with most of the newly formed dust. To study supernova dust production, we observe SNR 1E0102.2-7219, which is approximately 1000 years old with a reverse shock that has only reached into a small part of its ejecta making it an excellent candidate to search for newly formed dust that has not yet been destroyed by those shocks. Using Herschel data, we carefully model the background around the remnant to remove emission that is unrelated to the SNR. We then measure the mass, temperature, and chemical composition of the dust by fitting the spectral energy distribution. Our findings reveal a substantial amount of previously undetected cold dust in the remnant, suggesting that indeed core collapse supernovae may host substantial amounts of newly formed dust, at least prior to the passage of the reverse shock.

  5. Does apparent diffusion coefficient predict the degree of liver regeneration of donor and recipient after living donor liver transplantation?

    PubMed

    Morita, Koichiro; Nishie, Akihiro; Asayama, Yoshiki; Ishigami, Kousei; Ushijima, Yasuhiro; Takayama, Yukihisa; Okamoto, Daisuke; Fujita, Nobuhiro; Ikegami, Toru; Yoshizumi, Tomoharu; Shirabe, Ken; Honda, Hiroshi

    2017-05-01

    To elucidate the relationship between the ADCs of the liver graft and the remnant liver and the degree of liver regeneration in LDLT. 15 recipients and 15 corresponding donors underwent magnetic resonance imaging and computed tomography 1-2 weeks after living donor liver transplantation (LDLT). For diffusion-weighted imaging (DWI), a single-shot echo-planar sequence with b-factors of 0, 500, and 1000s/mm 2 was scanned. ADCs of the liver parenchyma were calculated at b factors of 0 and 500 and 1000 (ADC 0-500-1000) or 0 and 500 (ADC 0-500) or 500 and 1000 (ADC 500-1000). The liver volume ratio at LDLT, the mean ADCs and the regeneration rate were compared between the graft and the remnant liver using paired-t tests. The mean liver volume ratio of the recipients (41.3±9.8%) tended to be smaller than that of the donors (51.8±13.8%). The mean ADC 0-500 of the remnant liver (1.72±0.33) was significantly higher than that of the graft (1.43±0.32). The regeneration rate of the graft (2.07±0.41) was significantly higher than that of the remnant liver (1.53±0.49). ADC 0-500 can describe differences in blood perfusion between liver grafts and the remnant liver according to the degree of liver regeneration. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Very high-resolution observations of compact radio sources in the directions of supernova remnants

    NASA Technical Reports Server (NTRS)

    Geldzahler, B. J.; Shaffer, D. B.

    1981-01-01

    Compact radio sources whose positions lie within the outlines of supernova remnants may be the stellar remnants of supernova explosions and, if they are related to the supernova remnants, may be used to explore the nature of any morphological connection between the Galactic and extragalactic radio sources. Three such compact sources, G 127.11+0.54, CL 4, and 2051+433, have been observed at 10.65 GHz with an array of very long baseline interferometers having elements in the USA and West Germany. The radio source 2051+433 was also observed briefly at 5.01 GHz. The measured size of CL 4 at 10.65 GHz is about 0.0005 arcsec and seems to be dominated by the effects of interstellar scattering. No fringes were seen in 2051+433, and results indicate there is no compact component of 2051+433 smaller than 0.001 arcsec radiating at 10.65 GHz above a level of about 50 mJy. The possibility is presented that G 127.11+0.54 is a Galactic object. It is found to consist of two components separated by about 0.002 arcsec and oriented perpendicular to both the radio bridge of the supernova remnant G 127.1+0.5 and the underlying optical image. G 127.11+0.54, if Galactic, lies at the extreme low-luminosity end of an apparent continuum of Galactic and extragalactic compact radio source luminosities.

  7. Clinical outcomes of endoscopic submucosal dissection for early gastric cancer in remnant stomach or gastric tube.

    PubMed

    Nishide, N; Ono, H; Kakushima, N; Takizawa, K; Tanaka, M; Matsubayashi, H; Yamaguchi, Y

    2012-06-01

    Little information exists regarding the optimal treatment of early gastric cancer (EGC) in a remnant stomach or gastric tube. The aim of this study was to assess the feasibility and clinical outcomes of endoscopic submucosal dissection (ESD) for EGC in a remnant stomach and gastric tube. Between September 2002 and December 2009, ESD was performed in 62 lesions in 59 patients with EGC in a remnant stomach (48 lesions) or gastric tube (14 lesions). Clinicopathological data were retrieved retrospectively to assess the en bloc resection rate, complications, and outcomes. Treatment results were assessed according to the indications for endoscopic resection, and were compared with those of ESD performed in a whole stomach during the same study period. The en bloc resection rates for lesions within the standard and expanded indication were 100 % and 93 %, respectively. Postoperative bleeding occurred in five patients (8 %). The perforation rate was significantly higher (18 %, 11 /62) than that of ESD in a whole stomach (5 %, 69 /1479). Among the perforation cases, eight lesions involved the anastomotic site or stump line, and ulcerative changes were observed in five lesions. The 3-year overall survival rate was 85 %, with eight deaths due to other causes and no deaths from gastric cancer. A high en bloc resection rate was achieved by ESD for EGC in a remnant stomach or gastric tube; however, this procedure is still technically demanding due to the high complication rate of perforation. © Georg Thieme Verlag KG Stuttgart · New York.

  8. Extra-large remnant recoil velocities and spins from near-extremal-Bowen-York-spin black-hole binaries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dain, Sergio; Max Planck Institute for Gravitational Physics; Lousto, Carlos O.

    2008-07-15

    We evolve equal-mass, equal-spin black-hole binaries with specific spins of a/m{sub H}{approx}0.925, the highest spins simulated thus far and nearly the largest possible for Bowen-York black holes, in a set of configurations with the spins counteraligned and pointing in the orbital plane, which maximizes the recoil velocities of the merger remnant, as well as a configuration where the two spins point in the same direction as the orbital angular momentum, which maximizes the orbital hangup effect and remnant spin. The coordinate radii of the individual apparent horizons in these cases are very small and the simulations require very high centralmore » resolutions (h{approx}M/320). We find that these highly spinning holes reach a maximum recoil velocity of {approx}3300 km s{sup -1} (the largest simulated so far) and, for the hangup configuration, a remnant spin of a/m{sub H}{approx}0.922. These results are consistent with our previous predictions for the maximum recoil velocity of {approx}4000 km s{sup -1} and remnant spin; the latter reinforcing the prediction that cosmic censorship is not violated by merging highly spinning black-hole binaries. We also numerically solve the initial data for, and evolve, a single maximal-Bowen-York-spin black hole, and confirm that the 3-metric has an O(r{sup -2}) singularity at the puncture, rather than the usual O(r{sup -4}) singularity seen for nonmaximal spins.« less

  9. Two Archetypes of Motor Control Research.

    PubMed

    Latash, Mark L

    2010-07-01

    This reply to the Commentaries is focused on two archetypes of motor control research, one based on physics and physiology and the other based on control theory and ideas of neural computations. The former approach, represented by the equilibrium-point hypothesis, strives to discover the physical laws and salient physiological variables that make purposeful coordinated movements possible. The latter approach, represented by the ideas of internal models and optimal control, tries to apply methods of control developed for man-made inanimate systems to the human body. Specific issues related to control with subthreshold membrane depolarization, motor redundancy, and the idea of synergies are briefly discussed.

  10. The Burst and Transient Source Experiment (BATSE) Earth Occultation Catalog of Low-Energy Gamma-Ray Sources

    NASA Technical Reports Server (NTRS)

    Harmon, B. A.; Wilson, C. A.; Fishman, G. J.; Connaughton, V.; Henze, W.; Paciesas, W. S.; Finger, M. H.; McCollough, M. L.; Sahi, M.; Peterson, B.

    2004-01-01

    The Burst and Transient Source Experiment (BATSE), aboard the Compton Gamma Ray Observatory (CGRO), provided a record of the low-energy gamma-ray sky (approx. 20-1000 keV) between 1991 April and 2000 May (9.1 yr). BATSE monitored the high-energy sky using the Earth occultation technique (EOT) for point sources whose emission extended for times on the order of the CGRO orbital period (approx. 92 min) or greater. Using the EOT to extract flux information, a catalog of sources using data from the BATSE Large Area Detectors has been prepared. The first part of the catalog consists of results from the all-sky monitoring of 58 sources, mostly Galactic, with intrinsic variability on timescales of hours to years. For these sources, we have included tables of flux and spectral data, and outburst times for transients. Light curves (or flux histories) have been placed on the World Wide Web. We then performed a deep sampling of these 58 objects, plus a selection of 121 more objects, combining data from the entire 9.1 yr BATSE data set. Source types considered were primarily accreting binaries, but a small number of representative active galaxies, X-ray-emitting stars, and supernova remnants were also included. The sample represents a compilation of sources monitored and/or discovered with BATSE and other high-energy instruments between 1991 and 2000, known sources taken from the HEAO 1 A-4 and Macomb & Gehrels catalogs. The deep sample results include definite detections of 83 objects and possible detections of 36 additional objects. The definite detections spanned three classes of sources: accreting black hole and neutron star binaries, active galaxies, and Supernova remnants. The average fluxes measured for the fourth class, the X-ray emitting stars, were below the confidence limit for definite detection.

  11. Facies and Depositional History of Arc-Related, Deep-Marine Volcaniclastic Rocks in Core Recovered on International Ocean Discovery Program Expedition 351, Philippine Sea

    NASA Astrophysics Data System (ADS)

    Johnson, K. E.; Waldman, R.; Marsaglia, K. M.

    2016-12-01

    The Izu-Bonin-Mariana (IBM) Arc System, south of Japan, hosts a multitude of active and extinct (remnant) volcanic arcs and associated basins partly filled with volcanic sediment. Core extracted adjacent to the proto-IBM arc (Kyushu-Palau Ridge; KPR), in the Amami-Sankaku Basin (ASB) during International Ocean Discovery Program (IODP) Expedition 351, contains an incredibly well-preserved record of backarc sedimentation resulting from changing tectonic regimes during arc development and decline. Approximately 1000 meters of Eocene to Oligocene volcaniclastic sedimentary rocks were analyzed via shipboard core photos, core descriptions, and thin sections with the intention of understanding the depositional history at this site. A database of stratigraphic columns, 539 section and 147 core summaries, was created to display grain size trends, sedimentary structures, bedding characteristics, and facies changes. Individual depositional events were classified using existing and slightly modified classification schemes for muddy, sandy, and gravel-rich gravity flow deposits, as well as muddy deposits and tuffs. Downhole trends show repeating coarsening-upward intervals that grade from fine-grained turbidites to coarser turbidites and debrites. These trends indicate how the active depositional systems evolved upsection as the arc matured. Following arc initiation, facies deposited were primarily mud-rich; these coarsened-upward into 12 stacked sequences of submarine lobe and channel facies with sediment from one or more volcanic sources. These are interpreted to represent the building of the arc edifice that began 41 Ma. Four distinct periods of coarse lobe accumulation created a thick submarine fan over a period of nearly 13 million years. An abrupt shift to muddy turbidites at 30 Ma represents the onset of rifting of the paleo-IBM arc as backarc spreading in the Shikoku Basin was initiated and volcaniclastic supply to the ASB waned with formation of the KPR remnant arc.

  12. Eruptive history and geochronology of the Mount Baker volcanic field, Washington

    USGS Publications Warehouse

    Hildreth, W.; Fierstein, J.; Lanphere, M.

    2003-01-01

    Mount Baker, a steaming, ice-mantled, andesitic stratovolcano, is the most conspicuous component of a multivent Quaternary volcanic field active almost continuously since 1.3 Ma. More than 70 packages of lava flows and ~110 dikes have been mapped, ???500 samples chemically analyzed, and ~80 K-Ar and 40Ar/39Ar ages determined. Principal components are (1) the ignimbrite-filled Kulshan caldera (1.15 Ma) and its precaldera and postcaldera rhyodacite lavas and dikes (1.29-0.99 Ma); (2)~60 intracaldera, hydrothermally altered, andesite-dacite dikes and pods-remnants of a substantial early-postcaldera volcanic center (1.1-0.6 Ma); (3) unaltered intracaldera andesite lavas and dikes, including those capping Ptarmigan and Lasiocarpa Ridges and Table Mountain (0.5-0.2 Ma); (4) the long-lived Chowder Ridge focus (1.29-0.1 Ma)-an andesite to rhyodacite eruptive complex now glacially reduced to ~50 dikes and remnants of ~10 lava flows; (5) Black Buttes stratocone, basaltic to dacitic, and several contemporaneous peripheral volcanoes (0.5-0.2 Ma); and (6) Mount Baker stratocone and contemporaneous peripheral volcanoes (0.1 Ma to Holocene). Glacial ice has influenced eruptions and amplified erosion throughout the lifetime of the volcanic field. Although more than half the material erupted has been eroded, liberal and conservative volume estimates for 77 increments of known age yield cumulative curves of volume erupted vs. time that indicate eruption rates in the range 0.17-0.43 km3/k.y. for major episodes and longterm background rates of 0.02-0.07 km3/k.y. Andesite and rhyodacite each make up nearly half of the 161 ?? 56 km3 of products erupted, whereas basalt and dacite represent only a few cubic kilometers, each representing 1%-3% the total. During the past 4 m.y., the principal magmatic focus has migrated stepwise 25 km southwestward, from the edge of the Chilliwack batholith to present-day Mount Baker.

  13. Endocrown restorations: Influence of dental remnant and restorative material on stress distribution.

    PubMed

    Tribst, João Paulo Mendes; Dal Piva, Amanda Maria de Oliveira; Madruga, Camila Ferreira Leite; Valera, Marcia Carneiro; Borges, Alexandre Luiz Souto; Bresciani, Eduardo; de Melo, Renata Marques

    2018-06-20

    The goal of this study was to evaluate the stress distribution in a tooth/restoration system according to the factors "amount of dental remnant" (3 levels) and "restorative material" (2 levels). Three endodontically treated maxillary molars were modeled with CAD software for conducting non-linear finite element analysis (FEA), each with a determined amount of dental remnant of 1.5, 3, or 4.5mm. Models were duplicated, and half received restorations in lithium disilicate (IPS e.max CAD), while the other half received leucite ceramic restorations (IPS Empress CAD), both from Ivoclar Vivadent (Schaan, Liechtenstein). The solids were imported to analysis software (ANSYS 17.2, ANSYS Inc., Houston, TX, USA) in STEP format. All contacts involving the resin cement were considered no-separation, whereas between teeth and fixation cylinder, the contact was considered perfectly bonded. The mechanical properties of each structure were reported, and the materials were considered isotropic, linearly elastic, and homogeneous. An axial load (300N) was applied at the occlusal surface (triploidism area). Results were determined by colorimetric graphs of maximum principal stress (MPS) on tooth remnant, cement line, and restoration. MPS revealed that both factors influenced the stress distribution for all structures; the higher the material's elastic modulus, the higher the stress concentration on the restoration and the lower the stress concentration on the cement line. Moreover, the greater the dental crown remnant, the higher the stress concentration on the restoration. Thus, the remaining dental tissue should always be preserved. In situations in which few dental remnants are available, the thicker the restoration, the higher the concentration of stresses in its structure, protecting the adhesive interface from potential adhesive failures. Results are more promising when the endocrown is fabricated with lithium disilicate ceramic. Copyright © 2018 The Academy of Dental Materials. Published by Elsevier Inc. All rights reserved.

  14. Shocked Clouds in the Vela Supernova Remnant

    NASA Technical Reports Server (NTRS)

    Nichols, Joy S.; Slavin, Jonathan D.

    2004-01-01

    Unusually strong high-excitation C I has been detected in eleven lines of sight through the Vela supernova remnant by means of UV absorption-line studies of IUE data. Most of these lines of sight lie near the western edge of the X-ray bright region of the supernova remnant in a spatially distinct band approximately 1deg by 4deg oriented approximately north/south. The high-excitation C I (denoted C I*) is interpreted as evidence of a complex of shocked dense clouds inside the supernova remnant, due to the high pressures indicated in this region. To further analyze the properties of this region of C I*, we present new HIRES-processed IRAS data of the entire Vela SNR. A temperature map calculated from the HIRES IRAS data, based on a two-component dust model, reveals the signature of hot dust at several locations in the SNR. The hot dust is anti-correlated spatially with X-ray emission as revealed by ROSAT, as would be expected for a dusty medium interacting with a shock wave. The regions of hot dust are strongly correlated with optical filaments, supporting a scenario of dense clouds interior to the SNR that have been shocked and are now cooling behind the supernova blast wave. With few exceptions, the lines of sight to the strong C I* pass through regions of hot dust and optical filaments. Possible mechanisms for the production of the anomalously large columns of C I and C I* are discussed. Dense clouds on the back western hemisphere of the remnant may explain the relatively low X-ray emission in the western portion of the Vela supernova remnant due to the slower forward shock velocity in regions where the shock has encountered the dense clouds. An alternate explanation for the presence of neutral, excited state, and ionized species along the same line of sight may be a magnetic precusor that heats and compresses the gas ahead of the shock.

  15. On the Formation of Elliptical Galaxies via Mergers in Galaxy Groups

    NASA Astrophysics Data System (ADS)

    Taranu, Dan; Dubinski, John; Yee, Howard K. C.

    2015-01-01

    Giant elliptical galaxies have long been thought to form through gas-rich "major" mergers of two roughly equal-mass spiral galaxies. However, elliptical galaxies are often found at the centers of groups, and so are likely to have undergone several significant mergers. We test the hypothesis that ellipticals form through multiple, mainly minor and dry mergers in groups, using a novel sample of hundreds of N-body simulations of mergers in groups of three to twenty-five spiral galaxies.Realistic mock observations of the simulated central merger remnants show that they have comparable surface brightness profiles to observed ellipticals from SDSS and ATLAS3D - so long as the progenitor spirals begin with concentrated bulges. The remnants follow tight size-luminosity and velocity dispersion-luminosity relations (<0.12 dex scatter), with similar slopes as observed. Stochastic merging can produce tight scaling relations if the merging galaxies follow tight scaling relations themselves. However, the remnants are too large and have too low dispersions at fixed luminosity. Some remnants show substantial (v/σ > 0.1) rotational support, but most are slow rotators with v/σ << 0.5.Ellipticals also follow a tight "fundamental plane" scaling relation between size R, mean surface brightness μ and velocity dispersion σ: R ∝ σaμb, with small (<0.06 dex) scatter and significantly different coefficients from the expected scaling (a "tilt"). The remnants lie on a similar fundamental plane, with even smaller scatter (0.02 dex), as well as a tilt in the correct sense - albeit weaker than observed. This tilt is mainly driven by variable dark matter fractions within Reff, such that massive merger remnants have larger central dark matter fractions than their lower-mass counterparts.These results suggest that massive ellipticals can originate from multiple, mainly minor and dry mergers. However, significant gas dissipation may be needed to produce lower-mass, rapidly-rotating ellipticals.

  16. Liver remnant regeneration in donors after living donor liver transplantation: long-term follow-up using CT and MR imaging.

    PubMed

    Klink, T; Simon, P; Knopp, C; Ittrich, H; Fischer, L; Adam, G; Koops, A

    2014-06-01

    To assess liver remnant volume regeneration and maintenance, and complications in the long-time follow-up of donors after living donor liver transplantation using CT and MRI. 47 donors with a mean age of 33.5 years who donated liver tissue for transplantation and who were available for follow-up imaging were included in this retrospective study. Contrast-enhanced CT and MR studies were acquired for routine follow-up. Two observers evaluated pre- and postoperative images regarding anatomy and pathological findings. Volumes were manually measured on contrast-enhanced images in the portal venous phase, and potential postoperative complications were documented. Pre- and postoperative liver volumes were compared for evaluating liver remnant regeneration. 47 preoperative and 89 follow-up studies covered a period of 22.4 months (range: 1 - 84). After right liver lobe (RLL) donation, the mean liver remnant volume was 522.0 ml (± 144.0; 36.1 %; n = 18), after left lateral section (LLS) donation 1,121.7 ml (± 212.8; 79.9 %; n = 24), and after left liver lobe (LLL) donation 1,181.5 ml (± 279.5; 72.0 %; n = 5). Twelve months after donation, the liver remnant volume were 87.3 % (RLL; ± 11.8; n = 11), 95.0 % (LS; ± 11.6; n = 18), and 80.1 % (LLL; ± 2.0; n = 2 LLL) of the preoperative total liver volume. Rapid initial regeneration and maintenance at 80 % of the preoperative liver volume were observed over the total follow-up period.  Minor postoperative complications were found early in 4 patients. No severe or late complications or mortality occurred. Rapid regeneration of liver remnant volumes in all donors and volume maintenance over the long-term follow-up period of up to 84 months without severe or late complications are important observations for assessing the safety of LDLT donors. Liver remnant volumes of LDLT donors rapidly regenerated after donation and volumes were maintained over the long-term follow-up period of up to 84 months without severe or late complications. © Georg Thieme Verlag KG Stuttgart · New York.

  17. Whole-remnant and maximum-voxel SPECT/CT dosimetry in {sup 131}I-NaI treatments of differentiated thyroid cancer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mínguez, Pablo, E-mail: pablo.minguezgabina@osakid

    Purpose: To investigate the possible differences between SPECT/CT based whole-remnant and maximum-voxel dosimetry in patients receiving radio-iodine ablation treatment of differentiated thyroid cancer (DTC). Methods: Eighteen DTC patients were administered 1.11 GBq of {sup 131}I-NaI after near-total thyroidectomy and rhTSH stimulation. Two patients had two remnants, so in total dosimetry was performed for 20 sites. Three SPECT/CT scans were performed for each patient at 1, 2, and 3–7 days after administration. The activity, the remnant mass, and the maximum-voxel activity were determined from these images and from a recovery-coefficient curve derived from experimental phantom measurements. The cumulated activity was estimatedmore » using trapezoidal-exponential integration. Finally, the absorbed dose was calculated using S-values for unit-density spheres in whole-remnant dosimetry and S-values for voxels in maximum-voxel dosimetry. Results: The mean absorbed dose obtained from whole-remnant dosimetry was 40 Gy (range 2–176 Gy) and from maximum-voxel dosimetry 34 Gy (range 2–145 Gy). For any given patient, the activity concentrations for each of the three time-points were approximately the same for the two methods. The effective half-lives varied (R = 0.865), mainly due to discrepancies in estimation of the longer effective half-lives. On average, absorbed doses obtained from whole-remnant dosimetry were 1.2 ± 0.2 (1 SD) higher than for maximum-voxel dosimetry, mainly due to differences in the S-values. The method-related differences were however small in comparison to the wide range of absorbed doses obtained in patients. Conclusions: Simple and consistent procedures for SPECT/CT based whole-volume and maximum-voxel dosimetry have been described, both based on experimentally determined recovery coefficients. Generally the results from the two approaches are consistent, although there is a small, systematic difference in the absorbed dose due to differences in the S-values, and some variability due to differences in the estimated effective half-lives, especially when the effective half-life is long. Irrespective of the method used, the patient absorbed doses obtained span over two orders of magnitude.« less

  18. Endoscopic submucosal dissection for early gastric cancer in the remnant stomach after gastrectomy.

    PubMed

    Nonaka, Satoru; Oda, Ichiro; Makazu, Makomo; Haruyama, Shin; Abe, Seiichiro; Suzuki, Haruhisa; Yoshinaga, Shigetaka; Nakajima, Takeshi; Kushima, Ryoji; Saito, Yutaka

    2013-07-01

    Endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) after surgical gastrectomy is a technically difficult procedure because of the limited working space in the remnant stomach as well as the presence of severe gastric fibrosis and staples under the suture line. We evaluated clinical results including long-term outcomes to determine the feasibility and effectiveness of ESD for EGC in the remnant stomach of patients after gastrectomy. Retrospective study. National Cancer Center Hospital, Tokyo, Japan. We investigated patients undergoing ESD for EGC in the remnant stomach from 1997 to 2011. We examined the patient characteristics, endoscopic findings, technical results, adverse events, and histopathologic results including curability and evaluations of Helicobacter pylori gastritis in addition to the rates of local recurrence, metachronous gastric cancer, overall survival, and cause-specific survival. A total of 128 consecutive patients with 139 lesions had previously undergone 87 distal (68%), 25 proximal (19.5%) and 16 pylorus-preserving gastrectomies (12.5%). The median period from the original gastrectomy to the subsequent ESD for EGC in the remnant stomach was 5.7 years (range 0.6-51 years), the median tumor size was 13 mm (range 1-60 mm), and the median procedure time was 60 minutes (range 15-310 minutes). There were 131 en bloc resections (94%), with curative resections achieved for 109 lesions (78%); 22 lesions (16%) resulted in non-curative resections, and 8 lesions (6%) had only a horizontal margin positive or had inconclusive results. A total of 118 patients (92%) were assessed as H pylori gastritis-positive, with 7 patients (5%) negative. Adverse events included 2 cases of delayed bleeding (1.4%) and 2 perforations (1.4%), with 1 patient requiring emergency surgery. The 5-year overall and cause-specific survival rates were 87.3% and 100%, respectively, during a median follow-up period of 4.5 years (range 0-13.7 years), with no deaths from EGC in the remnant stomach. Single-center, retrospective study. ESD for EGC in the remnant stomach of patients after gastrectomy was a feasible and effective therapeutic method and should become the standard treatment in such cases, based on the favorable long-term outcomes. Copyright © 2013 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.

  19. A Microbial Perspective on the Grand Challenges in Comparative Animal Physiology

    PubMed Central

    2018-01-01

    ABSTRACT Interactions with microbial communities can have profound influences on animal physiology, thereby impacting animal performance and fitness. Therefore, it is important to understand the diversity and nature of host-microbe interactions in various animal groups (invertebrates, fish, amphibians, reptiles, birds, and mammals). In this perspective, I discuss how the field of host-microbe interactions can be used to address topics that have been identified as grand challenges in comparative animal physiology: (i) horizontal integration of physiological processes across organisms, (ii) vertical integration of physiological processes across organizational levels within organisms, and (iii) temporal integration of physiological processes during evolutionary change. Addressing these challenges will require the use of a variety of animal models and the development of systems approaches that can integrate large, multiomic data sets from both microbial communities and animal hosts. Integrating host-microbe interactions into the established field of comparative physiology represents an exciting frontier for both fields. PMID:29556549

  20. ROSAT PSPC Observations of CL0016+16

    NASA Technical Reports Server (NTRS)

    Hughes, John P.

    1996-01-01

    This report is an update of progress on NASA grant NAG5-2156. The following papers which were published or submitted since April 1966 were supported by this grant. Preprints of each are attached: HST Observations of Oxygen-rich Supernova Remnants in the Magellanic Clouds, and SuperNova Remnants Associated with Molecular Clouds in the Large Magellanic Cloud.

  1. X-ray emission from reverse-shocked ejecta in supernova remnants

    NASA Technical Reports Server (NTRS)

    Cioffi, Denis F.; Mckee, Christopher F.

    1990-01-01

    A simple physical model of the dynamics of a young supernova remnant is used to derive a straightforward kinematical description of the reverse shock. With suitable approximations, formulae can then be developed to give the X-ray emission of the reverse-shocked ejecta. The results are found to agree favorably with observations of SN1006.

  2. On The Origin Of Two-Shell Supernova Remnants

    NASA Astrophysics Data System (ADS)

    Gvaramadze, Vasilii

    2007-07-01

    The proper motion of massive stars could cause them to explode far from the geometric centers of their wind-driven bubbles and thereby could affect the symmetry of the resulting diffuse supernova remnants (SNRs). We use this fact to explain the origin of SNRs consisting of two partially overlapping shells (e.g. Cygnus Loop, 3C 400.2, etc.).

  3. Effect of urbanization on the structure and functional traits of remnant subtropical evergreen broad-leaved forests in South China

    Treesearch

    Liujing Huang; Hongfeng Chen; Hai Ren; Jun Wang; Qinfeng Guo

    2013-01-01

    We investigated the effects of major environmental drivers associated with urbanization on species diversity and plant functional traits (PFTs) in the remnant subtropical evergreen broad-leaved forests in Metropolitan Guangzhou (Guangdong, China). Twenty environmental factors including topography, light, and soil properties were used to quantify the effects of...

  4. Recombining plasma in the remnant of a core-collapsed supernova, Kes 17

    NASA Astrophysics Data System (ADS)

    Washino, Ryosaku; Uchida, Hiroyuki; Nobukawa, Masayoshi; Tsuru, Takeshi Go; Tanaka, Takaaki; Kawabata Nobukawa, Kumiko; Koyama, Katsuji

    2016-06-01

    We report on Suzaku results concerning Kes 17, a Galactic mixed-morphology supernova remnant. The X-ray spectrum of the whole Kes 17 is well explained by a pure thermal plasma, in which we found Lyα of Al XIII and Heα of Al XII, Ar XVII, and Ca XIX lines for the first time. The abundance pattern and the plasma mass suggest that Kes 17 is a remnant of a core-collapsed supernova of a 25-30 M⊙ progenitor star. The X-ray spectrum of the north region is expressed by a recombining plasma. The origin would be due to the cooling of electrons by thermal conduction to molecular clouds located near the north region.

  5. Onion-shell model of cosmic ray acceleration in supernova remnants

    NASA Technical Reports Server (NTRS)

    Bogdan, T. J.; Volk, H. J.

    1983-01-01

    A method is devised to approximate the spatially averaged momentum distribution function for the accelerated particles at the end of the active lifetime of a supernova remnant. The analysis is confined to the test particle approximation and adiabatic losses are oversimplified, but unsteady shock motion, evolving shock strength, and non-uniform gas flow effects on the accelerated particle spectrum are included. Monoenergetic protons are injected at the shock front. It is found that the dominant effect on the resultant accelerated particle spectrum is a changing spectral index with shock strength. High energy particles are produced in early phases, and the resultant distribution function is a slowly varying power law over several orders of magnitude, independent of the specific details of the supernova remnant.

  6. Evolution and Spectrum of the Radio Emission of Tycho's Supernova Remnant

    NASA Astrophysics Data System (ADS)

    Vinyaikin, E. N.

    2018-02-01

    The radio spectrum of Tycho's Supernova Remnant is constructed at frequencies 12.6-143 000 MHz for epoch 2010.3, taking into account the secular decrease in the radio flux density of the remnant at the rate d = -(0.46 ± 0.03)%/year: S_ν ^{3C10} (t = 2010.3) = (43.1 ± 1.8 Jy)(ν [GHz])^{ - (0.592 ± 0.019) + (0.041 ± 0.012)log (ν [GHz])} . The spectrum has positive curvature. The presence of a low-frequency turnover in the spectrum of the radio source 3C10 with its maximum at 7.7 MHz is predicted, due to absorption in the interstellar medium in the direction toward the source.

  7. Dynamics of supernova remnants in the Galactic centre.

    NASA Astrophysics Data System (ADS)

    Bortolas, E.; Mapelli, M.; Spera, M.

    The Galactic centre (GC) is a unique place to study the extreme dynamical processes occurring near a super-massive black hole (SMBH). Here we simulate a large set of binaries orbiting the SMBH while the primary member undergoes a supernova (SN) explosion, in order to study the impact of SN kicks on the orbits of stars and dark remnants in the GC. We find that SN explosions are efficient in scattering neutron stars and other light stars on new (mostly eccentric) orbits, while black holes (BHs) tend to retain memory of the orbit of their progenitor star. SN kicks are thus unable to eject BHs from the GC: a cusp of dark remnants may be lurking in the central parsec of our Galaxy.

  8. Is the Eagle Nebula powered by a hidden supernova remnant ?

    NASA Astrophysics Data System (ADS)

    Boulanger, Francois

    2008-10-01

    Spitzer observations of the Eagle nebula (M16) reveal the presence of a large (8 pc diameter) shell of dust heated to anomalously high temperatures. Modeling of dust excitation shows that the shell emission cannot be powered by the cluster UV radiation but that it can be accounted for by collisionally heated dust in a young (a few 1000 yrs) supernova remnant. We have re-analyzed deep Chandra observations that show diffuse emission consistent with this hypothesis, but also with galactic ridge emission. We propose a 50 ksec XMM observation to probe the spatial extent of the diffuse X-ray emission beyond the Spitzer shell. Absence of emission outside of this shell will strongly support the supernova remnant interpretation

  9. Fermi Large Area Telescope detection of a break in the gamma-ray spectrum of the supernova remnant Cassiopeia A [ Fermi-LAT detection of a break in the gamma-ray spectrum of the supernova remnant Cassiopeia A

    DOE PAGES

    Yuan, Yajie; Funk, Stefan; Jóhannesson, Gülauger; ...

    2013-12-02

    Here, we report on observations of the supernova remnant Cassiopeia A in the energy range from 100 MeV to 100 GeV using 44 months of observations from the Large Area Telescope on board the Fermi Gamma-Ray Space Telescope. We perform a detailed spectral analysis of this source and report on a low-energy break in the spectrum atmore » $$1.72^{+1.35}_{-0.89}$$ GeV. By comparing the results with models for the gamma-ray emission, we find that hadronic emission is preferred for the GeV energy range.« less

  10. The Fermi Gamma-Ray Space Telescope discovers the pulsar in the young galactic supernova remnant CTA 1.

    PubMed

    Abdo, A A; Ackermann, M; Atwood, W B; Baldini, L; Ballet, J; Barbiellini, G; Baring, M G; Bastieri, D; Baughman, B M; Bechtol, K; Bellazzini, R; Berenji, B; Blandford, R D; Bloom, E D; Bogaert, G; Bonamente, E; Borgland, A W; Bregeon, J; Brez, A; Brigida, M; Bruel, P; Burnett, T H; Caliandro, G A; Cameron, R A; Caraveo, P A; Carlson, P; Casandjian, J M; Cecchi, C; Charles, E; Chekhtman, A; Cheung, C C; Chiang, J; Ciprini, S; Claus, R; Cohen-Tanugi, J; Cominsky, L R; Conrad, J; Cutini, S; Davis, D S; Dermer, C D; de Angelis, A; de Palma, F; Digel, S W; Dormody, M; do Couto E Silva, E; Drell, P S; Dubois, R; Dumora, D; Edmonds, Y; Farnier, C; Focke, W B; Fukazawa, Y; Funk, S; Fusco, P; Gargano, F; Gasparrini, D; Gehrels, N; Germani, S; Giebels, B; Giglietto, N; Giordano, F; Glanzman, T; Godfrey, G; Grenier, I A; Grondin, M-H; Grove, J E; Guillemot, L; Guiriec, S; Harding, A K; Hartman, R C; Hays, E; Hughes, R E; Jóhannesson, G; Johnson, A S; Johnson, R P; Johnson, T J; Johnson, W N; Kamae, T; Kanai, Y; Kanbach, G; Katagiri, H; Kawai, N; Kerr, M; Kishishita, T; Kiziltan, B; Knödlseder, J; Kocian, M L; Komin, N; Kuehn, F; Kuss, M; Latronico, L; Lemoine-Goumard, M; Longo, F; Lonjou, V; Loparco, F; Lott, B; Lovellette, M N; Lubrano, P; Makeev, A; Marelli, M; Mazziotta, M N; McEnery, J E; McGlynn, S; Meurer, C; Michelson, P F; Mineo, T; Mitthumsiri, W; Mizuno, T; Moiseev, A A; Monte, C; Monzani, M E; Morselli, A; Moskalenko, I V; Murgia, S; Nakamori, T; Nolan, P L; Nuss, E; Ohno, M; Ohsugi, T; Okumura, A; Omodei, N; Orlando, E; Ormes, J F; Ozaki, M; Paneque, D; Panetta, J H; Parent, D; Pelassa, V; Pepe, M; Pesce-Rollins, M; Piano, G; Pieri, L; Piron, F; Porter, T A; Rainò, S; Rando, R; Ray, P S; Razzano, M; Reimer, A; Reimer, O; Reposeur, T; Ritz, S; Rochester, L S; Rodriguez, A Y; Romani, R W; Roth, M; Ryde, F; Sadrozinski, H F-W; Sanchez, D; Sander, A; Parkinson, P M Saz; Schalk, T L; Sellerholm, A; Sgrò, C; Siskind, E J; Smith, D A; Smith, P D; Spandre, G; Spinelli, P; Starck, J-L; Strickman, M S; Suson, D J; Tajima, H; Takahashi, H; Takahashi, T; Tanaka, T; Thayer, J B; Thayer, J G; Thompson, D J; Thorsett, S E; Tibaldo, L; Torres, D F; Tosti, G; Tramacere, A; Usher, T L; Van Etten, A; Vilchez, N; Vitale, V; Wang, P; Watters, K; Winer, B L; Wood, K S; Yasuda, H; Ylinen, T; Ziegler, M

    2008-11-21

    Energetic young pulsars and expanding blast waves [supernova remnants (SNRs)] are the most visible remains after massive stars, ending their lives, explode in core-collapse supernovae. The Fermi Gamma-Ray Space Telescope has unveiled a radio quiet pulsar located near the center of the compact synchrotron nebula inside the supernova remnant CTA 1. The pulsar, discovered through its gamma-ray pulsations, has a period of 316.86 milliseconds and a period derivative of 3.614 x 10(-13) seconds per second. Its characteristic age of 10(4) years is comparable to that estimated for the SNR. We speculate that most unidentified Galactic gamma-ray sources associated with star-forming regions and SNRs are such young pulsars.

  11. Iatrogenic hyperthyroidism does not promote weight loss or prevent ageing-related increases in body mass in thyroid cancer survivors.

    PubMed

    Polotsky, Hanah N; Brokhin, Matvey; Omry, Gal; Polotsky, Alex J; Tuttle, R Michael

    2012-04-01

    Thyroid cancer survivors represent a unique population in which the potential long-term effects of brief periods of intentional thyroid hormone withdrawal and/or prolonged periods of iatrogenic hyperthyroidism on body weight and body mass were evaluated. The objectives of this study were to characterize body mass changes over several years in a cohort of thyroid cancer patients with iatrogenic hyperthyroidism and to compare these changes with the expected weight gain in age-matched healthy control populations. We also evaluated the possibility that the method of preparation [thyroid hormone withdrawal (THW) vs recombinant human TSH (rhTSH)] for radioactive iodine remnant ablation may be associated with differences in body mass at the time of the final follow-up. DESIGN/SETTING/PATIENTS/INTERVENTIONS: A retrospective review identified 153 patients with thyroid cancer who underwent total thyroidectomy at one major medical centre. Of the 153 patients, 143 also had radioactive iodine remnant ablation: 70 after THW and 73 after rhTSH. Change in weight and BMI at 1-2 and 3-5 years of follow-up points were examined. Annualized weight variation within the cohort was compared with age-matched population controls expressed in kilogram/year. Significant weight gain was noted for the full cohort after 3-5 years of follow-up as compared to baseline (76 ± 21 kg at baseline vs 79 ± 23 kg at 3-5 years of follow-up, P < 0·01), which represented a 3·2% increase. Female and male patients with thyroid cancer experienced 0·46 and 0·94 kg/year gain in weight, respectively, which is similar or somewhat higher than previously published age-matched population controls (ranging from 0·23 to 0·34 kg/year). When expressed as per cent change and comparing the final weight to the pre-operative baseline, the rhTSH group experienced approximately a 1·7% increase in weight compared with the 3·9% increase seen with THW patients (P = 0·02). When expressed as kg/year change, the rhTSH cohort had 0·34 kg/year change compared with the 0·64 kg/year change seen in the thyroid hormone withdrawal patients (P = 0·02). In otherwise, healthy patients with differentiated thyroid cancer, significant weight gain occurred during the 3-5 years of follow-up despite ongoing thyrotropin suppression. The data suggest that mild iatrogenic hyperthyroidism does not promote weight loss or prevent ageing-related weight gain. Greater weight gain was seen in patients prepared for radioactive remnant ablation with THW than with rhTSH. © 2012 Blackwell Publishing Ltd.

  12. Variable setpoint as a relaxing component in physiological control.

    PubMed

    Risvoll, Geir B; Thorsen, Kristian; Ruoff, Peter; Drengstig, Tormod

    2017-09-01

    Setpoints in physiology have been a puzzle for decades, and especially the notion of fixed or variable setpoints have received much attention. In this paper, we show how previously presented homeostatic controller motifs, extended with saturable signaling kinetics, can be described as variable setpoint controllers. The benefit of a variable setpoint controller is that an observed change in the concentration of the regulated biochemical species (the controlled variable) is fully characterized, and is not considered a deviation from a fixed setpoint. The variation in this biochemical species originate from variation in the disturbances (the perturbation), and thereby in the biochemical species representing the controller (the manipulated variable). Thus, we define an operational space which is spanned out by the combined high and low levels of the variations in (1) the controlled variable, (2) the manipulated variable, and (3) the perturbation. From this operational space, we investigate whether and how it imposes constraints on the different motif parameters, in order for the motif to represent a mathematical model of the regulatory system. Further analysis of the controller's ability to compensate for disturbances reveals that a variable setpoint represents a relaxing component for the controller, in that the necessary control action is reduced compared to that of a fixed setpoint controller. Such a relaxing component might serve as an important property from an evolutionary point of view. Finally, we illustrate the principles using the renal sodium and aldosterone regulatory system, where we model the variation in plasma sodium as a function of salt intake. We show that the experimentally observed variations in plasma sodium can be interpreted as a variable setpoint regulatory system. © 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

  13. Cosmic Ornament of Gas and Dust

    NASA Technical Reports Server (NTRS)

    2007-01-01

    [figure removed for brevity, see original site] 4-Panel Version Figure 1 [figure removed for brevity, see original site] [figure removed for brevity, see original site] [figure removed for brevity, see original site] Silicon Gas Figure 2 Argon Figure 3 Dust Collection Figure 4

    This beautiful bulb might look like a Christmas ornament but it is the blown-out remains of a stellar explosion, or supernova. Called Cassiopeia A, this supernova remnant is located about 10,000 light-years away in our own Milky Way galaxy. The remains are shown here in an infrared composite from NASA's Spitzer Space Telescope. Silicon gas is blue and argon gas is green, while red represents about 10,000 Earth masses worth of dust. Yellow shows areas where red and green overlap.

    The fact that these two features line up (as seen in yellow in the combined view) tells astronomers that the dust, together with the gas, was created in the explosion. This is the best evidence yet that supernovae are a significant source of dust in the early universe something that was postulated before, but not proven. Dust in our young universe is important because it eventually made its way into future stars, planets and even people.

    In figure 1, the upper left panel is a composite made up of three infrared views shown in the remaining panels. The bottom left view (figure 3) shows argon gas (green) that was synthesized as it was ejected from the star. The upper right panel (figure 2) shows silicon gas (blue) deep in the interior of the remnant. This cooler gas, called the unshocked ejecta, was also synthesized in the supernova blast. The bottom right view (figure 4) shows a collection of dust (red), including proto-silicates, silicate dioxide and iron oxide.

    The data for these images were taken by Spitzer's infrared spectrograph, which splits light apart to reveal the fingerprints of molecules and elements. In total, Spitzer collected separate 'spectra' at more than 1,700 positions across Cassiopeia A. Astronomers then created maps from this massive grid of data, showing the remnant in a multitude of infrared colors.

  14. Metal films on the surfaces and within diamond crystals from Arkhangelskaya and Yakutian diamond provinces

    NASA Astrophysics Data System (ADS)

    Makeev, A. B.; Kriulina, G. Yu.

    2012-12-01

    Representative samples of diamonds from five kimberlite pipes (Lomonosovskaya, Archangel'sk, Snegurochka, XXIII Congress of the Communist Party of the Soviet Union (CPSU), and Internationalnaya) of the Arkhangelskaya and Yakutian diamond provinces in Russia have been studied. Thirty-three varieties of metal films have been identified as syngenetic associated minerals. The films consist of 15 chemical elements that occur in the form of native metals and their natural alloys. Remnants of metal films were detected within diamond crystals. The metal films coating diamonds are a worldwide phenomenon. To date, these films have been described from Europe, Asia, South America, and Africa. Native metals, their alloys, and intermetallides are actual companion minerals of diamond.

  15. Taking the Radio Blinders Off of M83: A Wide Spectrum Analysis of the Historical Point Source Population

    NASA Astrophysics Data System (ADS)

    Stockdale, Christopher; Keefe, Clayton; Nichols, Michael; Rujevcan, Colton; Blair, William P.; Cowan, John J.; Godfrey, Leith; Miller-Jones, James; Kuntz, K. D.; Long, Knox S.; Maddox, Larry A.; Plucinsky, Paul P.; Pritchard, Tyler A.; Soria, Roberto; Whitmore, Bradley C.; Winkler, P. Frank

    2015-01-01

    We present low frequency observations of the grand design spiral galaxy, M83, using the C and L bands of the Karl G. Jansky Very Large Array (VLA). With recent optical (HST) and X-ray (Chandra) observations and utilizing the newly expanded bandwidth of the VLA, we are exploring the radio spectral properties of the historical radio point sources in M83. These observations allow us to probe the evolution of supernova remnants (SNRs) and to find previously undiscovered SNRs. These observations represent the fourth epoch of deep VLA observations of M83. The National Radio Astronomy Observatory is a facility of the National Science Foundation operated under cooperative agreement by Associated Universities.

  16. Generation, Characterization and Application of Antibodies Directed against HERV-H Gag Protein in Colorectal Samples

    PubMed Central

    Mullins, Christina S.; Hühns, Maja; Krohn, Mathias; Peters, Sven; Cheynet, Valérie; Oriol, Guy; Guillotte, Michèle; Ducrot, Sandrine; Mallet, François; Linnebacher, Michael

    2016-01-01

    Introduction A substantial part of the human genome originates from transposable elements, remnants of ancient retroviral infections. Roughly 8% of the human genome consists of about 400,000 LTR elements including human endogenous retrovirus (HERV) sequences. Mainly, the interplay between epigenetic and post-transcriptional mechanisms is thought to silence HERV expression in most physiological contexts. Interestingly, aberrant reactivation of several HERV-H loci appears specific to colorectal carcinoma (CRC). Results The expression of HERV-H Gag proteins (Gag-H) was assessed using novel monoclonal mouse anti Gag-H antibodies. In a flow cytometry screen four antibody clones were tested on a panel of primary CRC cell lines and the most well performing ones were subsequently validated in western blot analysis. Finally, Gag-H protein expression was analyzed by immune histology on cell line cytospins and on clinical samples. There, we found a heterogeneous staining pattern with no background staining of endothelial, stromal and infiltrating immune cells but diffuse staining of the cytoplasm for positive tumor and normal crypt cells of the colonic epithelium. Conclusion Taken together, the Gag-H antibody clone(s) present a valuable tool for staining of cells with colonic origin and thus form the basis for future more detailed investigations. The observed Gag-H protein staining in colonic epithelium crypt cells demands profound analyses of a potential role for Gag-H in the normal physiology of the human gut. PMID:27119520

  17. A Touch of Neuroscience

    ERIC Educational Resources Information Center

    Parlier, David; Demetrikopoulos, Melissa K.

    2004-01-01

    Middle school students represent a wonderful target audience for introducing neurological concepts. The preteen years of the middle grades represent a time of incredible physical and mental development. Students in a seventh-grade classroom are experiencing dramatic physiological and psychological changes. Understanding the parts and functions of…

  18. Toward the Understanding of the Physical Origin of Recombining Plasma in the Supernova Remnant IC 443

    NASA Astrophysics Data System (ADS)

    Matsumura, Hideaki; Tanaka, Takaaki; Uchida, Hiroyuki; Okon, Hiromichi; Tsuru, Takeshi Go

    2017-12-01

    We perform a spatially resolved spectroscopic analysis of X-ray emission from the supernova remnant (SNR) IC 443 with Suzaku. All of the spectra are well reproduced by a model consisting of a collisional ionization equilibrium (CIE) and two recombining plasma (RP) components. Although previous X-ray studies found an RP in the northeastern region, this is the first report on RPs in the other parts of the remnant. The electron temperature, kT e , of the CIE component is almost uniform at ∼0.2 keV across the remnant. The CIE plasma has metal abundances consistent with solar and is concentrated toward the rim of the remnant, suggesting that it is of shocked interstellar medium origin. The two RP components have different kT e : one in the range of 0.16–0.28 keV and the other in the range of 0.48–0.67 keV. The electron temperatures of both RP components decrease toward the southeast, where the SNR shock is known to be interacting with a molecular cloud. We also find the normalization ratio of the lower-kT e RP to higher-kT e RP components increases toward the southeast. Both results suggest the X-ray emitting plasma in the southeastern region is significantly cooled by some mechanism. One of the plausible cooling mechanisms is a thermal conduction between the hot plasma and the molecular cloud. If the cooling proceeds faster than the recombination timescale of the plasma, the same mechanism can account for the recombining plasma as well.

  19. A Deep X-Ray View of the Synchrotron-dominated Supernova Remnant G330.2+1.0

    NASA Astrophysics Data System (ADS)

    Williams, Brian J.; Hewitt, John W.; Petre, Robert; Temim, Tea

    2018-03-01

    We present moderately deep (125 ks) XMM-Newton observations of supernova remnant G330.2+1.0. This remnant is one of only a few known that fall into the “synchrotron-dominated” category, with the emission almost entirely dominated by a nonthermal continuum. Previous X-ray observations could only characterize the spectra of a few regions. Here, we examine the spectra from 14 regions surrounding the entire rim, finding that the spectral properties of the nonthermal emission do not vary significantly in any systematic way from one part of the forward shock to another, unlike several other remnants of this class. We confirm earlier findings that the power-law index, Γ, ranges from about 2.1–2.5, while the absorbing column density is generally between (2.0–2.6) × 1022 cm‑2. Fits with the srcut model find values of the roll-off frequency in the range of 1017.1–1017.5 Hz, implying energies of accelerated electrons of ∼100 TeV. These values imply a high shock velocity of ∼4600 km s‑1, favoring a young age of the remnant. Diffuse emission from the interior is nonthermal in origin as well, and fits to these regions yield similar values to those along the rim, also implying a young age. Thermal emission is present in the east, and the spectrum is consistent with a ∼650 km s‑1 shock wave encountering interstellar or circumstellar material with a density of ∼1 cm‑3.

  20. Congenital cutaneous fistula at the sternoclavicular joint - Not a dermoid fistula but the remnant of the fourth branchial (pharyngeal) cleft ?

    PubMed

    Ohno, Michinobu; Kanamori, Yutaka; Tomonaga, Kotaro; Yamashita, Tatsuya; Migita, Misato; Takezoe, Toshiko; Watanabe, Toshihiko; Fuchimoto, Yasushi; Matsuoka, Kentaro

    2015-12-01

    A fourth branchial pouch remnant is well known as a pyriform sinus fistula. However, there has been no report of a fistula composed of the complete remnant of the fourth branchial apparatus. We experienced patients with a congenital lower neck cutaneous fistula which was thought to be the skin-side remnant of the fourth branchial cleft. Seven children were referred to our hospital from 2009 to 2015 for the treatment of a cutaneous fistula situated near the sternoclavicular joint. All of them were surgically resected and their pathological characteristics were examined. Clinical charts were retrospectively reviewed. In six cases, the left side was affected. All cutaneous fistulas had a small skin orifice near the sternoclavicular joint and they were situated at the anterior edge of the sternocleidomastoid muscle. Abscess formation was seen in four cases. Surgical resection was performed at the age of 6 months to 9 years. These fistulas ran deep into the subcutaneous tissue and had a blind end. Pathological examination showed that the epithelial layer was mainly composed of a stratified squamous epithelium. In two cases the epithelium was composed of ciliated columnar epithelium. Recurrence has not been observed in any of the cases. The seven cases had a common clinical feature and were a definite clinical entity. Judging from the characteristics of our cases and the previous literature, we concluded that this lower neck cutaneous fistula was most likely a congenital skin-side remnant of the fourth branchial cleft. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  1. Duty-cycle and energetics of remnant radio-loud AGN

    NASA Astrophysics Data System (ADS)

    Turner, Ross J.

    2018-05-01

    Deriving the energetics of remnant and restarted active galactic nuclei (AGNs) is much more challenging than for active sources due to the complexity in accurately determining the time since the nucleus switched-off. I resolve this problem using a new approach that combines spectral ageing and dynamical models to tightly constrain the energetics and duty-cycles of dying sources. Fitting the shape of the integrated radio spectrum yields the fraction of the source age the nucleus is active; this, in addition to the flux density, source size, axis ratio, and properties of the host environment, provides a constraint on dynamical models describing the remnant radio source. This technique is used to derive the intrinsic properties of the well-studied remnant radio source B2 0924+30. This object is found to spend 50_{-12}^{+14} Myr in the active phase and a further 28_{-5}^{+6} Myr in the quiescent phase, have a jet kinetic power of 3.6_{-1.7}^{+3.0}× 10^{37} W, and a lobe magnetic field strength below equipartition at the 8σ level. The integrated spectra of restarted and intermittent radio sources are found to yield a `steep-shallow' shape when the previous outburst occurred within 100 Myr. The duty-cycle of B2 0924+30 is hence constrained to be δ < 0.15 by fitting the shortest time to the previous comparable outburst that does not appreciably modify the remnant spectrum. The time-averaged feedback energy imparted by AGNs into their host galaxy environments can in this manner be quantified.

  2. An explanation of the formation of the peculiar periphery of Tycho's supernova remnant

    NASA Astrophysics Data System (ADS)

    Fang, Jun; Yu, Huan; Zhang, Li

    2018-02-01

    Tycho's supernova remnant (SNR) has a periphery that clearly deviates from a spherical shape, based on X-ray and radio observations. The forward shock from the south-east to the north of the remnant has a deformed outline with a depression in the east, although in the west it is generally round and smooth. Moreover, at some locations in the shell, the supernova ejecta is located close to the forward shock, resulting in protrusions. Using 3D hydrodynamical simulations, we studied the dynamical evolution of the supernova ejecta in an inhomogeneous medium and the formation process of the profile of the forward shock. In order to reproduce the peculiar periphery of the remnant, we propose a model in which the supernova ejecta has evolved in a cavity blown by a latitude-dependent outflow. The results indicate that the depression to the east and the protrusion to the south-east on the observed periphery of the remnant can be generally reproduced if we assume a wind bubble driven by an anisotropic wind with a mass-loss rate of ˜10-7 M⊙ yr-1, a pole velocity of ˜100 km s-1, a duration of ˜105 yr prior to the supernova explosion, and a spatial velocity of ˜30 km s-1 of the progenitor with respect to the circumstellar medium. In conclusion, an explanation of the peculiar shape of the periphery of Tycho's SNR is that the supernova ejecta evolved in the cavity driven by a latitude-dependent wind.

  3. Reverse intestinal rotation: a rare case of volvulus around a vitelline duct remnant

    PubMed Central

    Dreyer, Stephan; Kaczynski, Jakub; Hrobar, Petr; Collins, Patrick

    2014-01-01

    We present a rare case of reverse intestinal rotation with volvulus around a Meckel's diverticulum attached to a vitelline duct remnant. The diagnosis was established by CT. The patient was treated with exploratory laparotomy and small bowel resection. The patient made a full recovery and was discharged home on the seventh postoperative day. PMID:25246458

  4. Bat activity at remnant oak trees in California Central Coast vineyards

    Treesearch

    William D. Tietje; Ted Weller; Christopher C. Yim

    2015-01-01

    During 1990 to 2013, the area planted with wine grapes increased nearly 4.5 times in San Luis Obispo County. Much of this development occurred on open oak savanna with scattered oak (Quercus spp.) trees. Remnant trees are retained in some vineyards, but their value to biodiversity retention has not been quantified. During April to September 2014,...

  5. Detection of Blood in Stable Flies (Diptera: Muscidae) with Hemoccult® Test Strips

    USDA-ARS?s Scientific Manuscript database

    Hemoccult® test kits were used to detect the remnants of blood meals in stable flies. The strips were able to detect remnants of blood meals in > 90% of the stable flies up to 8 days after blood feeding. This can be compared with detecting blood in the gut visually which was possible in less than 5%...

  6. Centrioles are freed from cilia by severing prior to mitosis.

    PubMed

    Parker, Jeremy D K; Hilton, Laura K; Diener, Dennis R; Rasi, M Qasim; Mahjoub, Moe R; Rosenbaum, Joel L; Quarmby, Lynne M

    2010-07-01

    Cilia are necessary for normal tissue development and homeostasis and are generally present during interphase, but not in mitosis. The precise mechanism of premitotic ciliary loss has been controversial, with data supporting either sequential disassembly through the transition zone or, alternatively, a severing event at the base of the cilia. Here we show by live cell imaging and immunofluorescence microscopy that resorbing flagella of Chlamydomonas leave remnants associated with the mother cell wall. We postulated that the remnants are the product of severing of doublet microtubules between the basal bodies and the flagellar transition zone, thereby freeing the centrioles to participate in spindle organization. We show via TEM that flagellar remnants are indeed flagellar transition zones encased in vesicles derived from the flagellar membrane. This transition zone vesicle can be lodged within the cell wall or it can be expelled into the environment. This process is observable in Chlamydomonas, first because the released flagellar remnants can remain associated with the cell by virtue of attachments to the cell wall, and second because the Chlamydomonas transition zone is particularly rich with electron-dense structure. However, release of basal bodies for spindle-associated function is likely to be conserved among the eukaryotes. 2010 Wiley-Liss, Inc.

  7. Evidence for the Stochastic Acceleration of Secondary Antiprotons by Supernova Remnants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cholis, Ilias; Hooper, Dan; Linden, Tim

    2017-01-16

    The antiproton-to-proton ratio in the cosmic-ray spectrum is a sensitive probe of new physics. Using recent measurements of the cosmic-ray antiproton and proton fluxes in the energy range of 1-1000 GeV, we study the contribution to themore » $$\\bar{p}/p$$ ratio from secondary antiprotons that are produced and subsequently accelerated within individual supernova remnants. We consider several well-motivated models for cosmic-ray propagation in the interstellar medium and marginalize our results over the uncertainties related to the antiproton production cross section and the time-, charge-, and energy-dependent effects of solar modulation. We find that the increase in the $$\\bar{p}/p$$ ratio observed at rigidities above $$\\sim$$ 100 GV cannot be accounted for within the context of conventional cosmic-ray propagation models, but is consistent with scenarios in which cosmic-ray antiprotons are produced and subsequently accelerated by shocks within a given supernova remnant. In light of this, the acceleration of secondary cosmic rays in supernova remnants is predicted to substantially contribute to the cosmic-ray positron spectrum, accounting for a significant fraction of the observed positron excess.« less

  8. Estimation of Time-Varying Pilot Model Parameters

    NASA Technical Reports Server (NTRS)

    Zaal, Peter M. T.; Sweet, Barbara T.

    2011-01-01

    Human control behavior is rarely completely stationary over time due to fatigue or loss of attention. In addition, there are many control tasks for which human operators need to adapt their control strategy to vehicle dynamics that vary in time. In previous studies on the identification of time-varying pilot control behavior wavelets were used to estimate the time-varying frequency response functions. However, the estimation of time-varying pilot model parameters was not considered. Estimating these parameters can be a valuable tool for the quantification of different aspects of human time-varying manual control. This paper presents two methods for the estimation of time-varying pilot model parameters, a two-step method using wavelets and a windowed maximum likelihood estimation method. The methods are evaluated using simulations of a closed-loop control task with time-varying pilot equalization and vehicle dynamics. Simulations are performed with and without remnant. Both methods give accurate results when no pilot remnant is present. The wavelet transform is very sensitive to measurement noise, resulting in inaccurate parameter estimates when considerable pilot remnant is present. Maximum likelihood estimation is less sensitive to pilot remnant, but cannot detect fast changes in pilot control behavior.

  9. A population of isolated hard X-ray sources near the supernova remnant Kes 69

    NASA Astrophysics Data System (ADS)

    Bocchino, F.; Bykov, A. M.; Chen, Y.; Krassilchtchikov, A. M.; Levenfish, K. P.; Miceli, M.; Pavlov, G. G.; Uvarov, Yu. A.; Zhou, X.

    2012-05-01

    Recent X-ray observations of the supernova remnant (SNR) IC 443 interacting with molecular clouds detected a new population of hard X-ray sources related to the remnant itself, which has been proposed to be fast ejecta fragments propagating within the dense environment. Encouraged by these studies, we obtained a deep XMM-Newton observation of the SNR Kes 69, which also shows signs of a shock-cloud interaction. We report on the detection of 18 hard X-ray sources in the field of Kes 69, which is a number sognificantly higher than expected for the Galactic source population in the field. The sources are spatially correlated with CO emission from the cloud in the remnant environment. The spectra of 3 of the 18 sources can be described as hard power-laws with photon indices smaller than two plus line emission associated with K-shell transitions. We discuss the two most promising scenarios for the interpretation of the sources, namely fast ejecta fragments (as in IC 443) and cataclysmic variables. While most of the observational evidence is consistent with the former interpretation, we cannot rule out the latter.

  10. Demographic mechanisms underpinning genetic assimilation of remnant groups of a large carnivore

    USGS Publications Warehouse

    Mikle, Nathaniel; Graves, Tabitha A.; Kovach, Ryan P.; Kendall, Katherine C.; Macleod, Amy C.

    2016-01-01

    Current range expansions of large terrestrial carnivores are occurring following human-induced range contraction. Contractions are often incomplete, leaving small remnant groups in refugia throughout the former range. Little is known about the underlying ecological and evolutionary processes that influence how remnant groups are affected during range expansion. We used data from a spatially explicit, long-term genetic sampling effort of grizzly bears (Ursus arctos) in the Northern Continental Divide Ecosystem (NCDE), USA, to identify the demographic processes underlying spatial and temporal patterns of genetic diversity. We conducted parentage analysis to evaluate how reproductive success and dispersal contribute to spatio-temporal patterns of genetic diversity in remnant groups of grizzly bears existing in the southwestern (SW), southeastern (SE) and east-central (EC) regions of the NCDE. A few reproductively dominant individuals and local inbreeding caused low genetic diversity in peripheral regions that may have persisted for multiple generations before eroding rapidly (approx. one generation) during population expansion. Our results highlight that individual-level genetic and reproductive dynamics play critical roles during genetic assimilation, and show that spatial patterns of genetic diversity on the leading edge of an expansion may result from historical demographic patterns that are highly ephemeral.

  11. Is the Link Between the Observed Velocities of Neutron Stars and their Progenitors a Simple Mass Relationship?

    NASA Astrophysics Data System (ADS)

    Bray, J. C.

    2017-11-01

    While the imparting of velocity `kicks' to compact remnants from supernovae is widely accepted, the relationship of the `kick' to the progenitor is not. We propose the `kick' is predominantly a result of conservation of momentum between the ejected and compact remnant masses. We propose the `kick' velocity is given by v kick = α(M ejecta/M remnant)+β, where α and β are constants we wish to determine. To test this we use the BPASS v2 (Binary Population and Spectral Synthesis) code to create stellar populations from both single star and binary star evolutionary pathways. We then use our Remnant Ejecta and Progenitor Explosion Relationship (REAPER) code to apply `kicks' to neutron stars from supernovae in these models using a grid of α and β values, (from 0 to 200 km s-1 in steps of 10 km s-1), in three different `kick' orientations, (isotropic, spin-axis aligned and orthogonal to spin-axis) and weighted by three different Salpeter initial mass functions (IMF's), with slopes of -2.0, -2.35 and -2.70. We compare our synthetic 2D and 3D velocity probability distributions to the distributions provided by Hobbs et al. (1995).

  12. Demographic mechanisms underpinning genetic assimilation of remnant groups of a large carnivore

    PubMed Central

    Kovach, Ryan; Kendall, Katherine C.; Macleod, Amy C.

    2016-01-01

    Current range expansions of large terrestrial carnivores are occurring following human-induced range contraction. Contractions are often incomplete, leaving small remnant groups in refugia throughout the former range. Little is known about the underlying ecological and evolutionary processes that influence how remnant groups are affected during range expansion. We used data from a spatially explicit, long-term genetic sampling effort of grizzly bears (Ursus arctos) in the Northern Continental Divide Ecosystem (NCDE), USA, to identify the demographic processes underlying spatial and temporal patterns of genetic diversity. We conducted parentage analysis to evaluate how reproductive success and dispersal contribute to spatio-temporal patterns of genetic diversity in remnant groups of grizzly bears existing in the southwestern (SW), southeastern (SE) and east-central (EC) regions of the NCDE. A few reproductively dominant individuals and local inbreeding caused low genetic diversity in peripheral regions that may have persisted for multiple generations before eroding rapidly (approx. one generation) during population expansion. Our results highlight that individual-level genetic and reproductive dynamics play critical roles during genetic assimilation, and show that spatial patterns of genetic diversity on the leading edge of an expansion may result from historical demographic patterns that are highly ephemeral. PMID:27655768

  13. Radio to Gamma-Ray Emission from Shell-Type Supernova Remnants: Predictions from Non-Linear Shock Acceleration Models

    NASA Technical Reports Server (NTRS)

    Baring, Matthew G.; Ellison, Donald C.; Reynolds, Stephen P.; Grenier, Isabelle A.; Goret, Philippe

    1998-01-01

    Supernova remnants (SNRs) are widely believed to be the principal source of galactic cosmic rays, produced by diffusive shock acceleration in the environs of the remnant's expanding blast wave. Such energetic particles can produce gamma-rays and lower energy photons via interactions with the ambient plasma. The recently reported observation of TeV gamma-rays from SN1006 by the CANGAROO Collaboration, combined with the fact that several unidentified EGRET sources have been associated with known radio/optical/X-ray-emitting remnants, provides powerful motivation for studying gamma-ray emission from SNRs. In this paper, we present results from a Monte Carlo simulation of non-linear shock structure and acceleration coupled with photon emission in shell-like SNRs. These non-linearities are a by-product of the dynamical influence of the accelerated cosmic rays on the shocked plasma and result in distributions of cosmic rays which deviate from pure power-laws. Such deviations are crucial to acceleration efficiency considerations and impact photon intensities and spectral shapes at all energies, producing GeV/TeV intensity ratios that are quite different from test particle predictions.

  14. Comparative biochemistry and physiology in Brazil: a critical appraisal.

    PubMed

    Navas, Carlos Arturo; Chaui-Berlinck, José Guilherme; Bicudo, José Eduardo P W; Pivello, Vânia R; Martins, Marcio

    2007-07-01

    Brazil stood out as the country with the highest number of submissions to the editorial project dedicated to Latin America by the journal Comparative Biochemistry and Physiology. Therefore, we felt that it was important to critically discuss the state of comparative biochemistry and physiology in this country. Our study is based on data collected from the ISI Web-of-Science. We analyzed publication trends through time, availability of novel approaches and techniques, patterns of collaboration among different geographical regions, patterns of collaboration with researchers abroad, and relative efforts dedicated to the study of biochemical and physiological adaptation of native fauna representing different terrestrial Brazilian biomes. Overall, our data shows that comparative biochemistry and physiology is a lively and productive discipline, but that some biases limit the scope of the field in Brazil. Some important limitations are the very heterogeneous distribution of research nuclei throughout the country and the absence of some important approaches, such as remote sensing and the use of molecular biology techniques in a comparative or evolutionary context. We also noticed that international collaboration far surpasses interregional collaboration, and discuss the possible causes and consequences of this situation. Finally, we found that Brazilian comparative biochemistry and physiology is biome-biased, as the Amazonian fauna has received far more attention than the whole pool of fauna representing other terrestrial biomes. We discuss the possible causes of these biases, and propose some directions that may contribute to invigorate the field in the country.

  15. Proteins regulating the biosynthesis and inactivation of neuromodulatory fatty acid amides.

    PubMed

    Patricelli, M P; Cravatt, B F

    2001-01-01

    Fatty acid amides (FAAs) represent a growing family of biologically active lipids implicated in a diverse range of cellular and physiological processes. At present, two general types of fatty acid amides, the N-acylethanolamines (NAEs) and the fatty acid primary amides (FAPAs), have been identified as potential physiological neuromodulators/neurotransmitters in mammals. Representative members of these two subfamilies include the endocannabinoid NAE anandamide and the sleep-inducing FAPA oleamide. In this Chapter, molecular mechanisms proposed for the biosynthesis and inactivation of FAAs are critically evaluated, with an emphasis placed on the biochemical and cell biological properties of proteins thought to mediate these processes.

  16. NuSTAR Detection of a Hard X-Ray Source in the Supernova Remnant-molecular Cloud Interaction Site of IC 443

    NASA Astrophysics Data System (ADS)

    Zhang, Shuo; Tang, Xiaping; Zhang, Xiao; Sun, Lei; Gotthelf, Eric V.; Zhang, Zhi-Yu; Li, Hui; Cheng, Allen; Pasham, Dheeraj; Baganoff, Frederick K.; Perez, Kerstin; Hailey, Charles J.; Mori, Kaya

    2018-06-01

    We report on a broadband study of a complex X-ray source (1SAX J0618.0+2227) associated with the interaction site of the supernova remnant (SNR) IC 443 and ambient molecular cloud (MC) using NuSTAR, XMM-Newton, and Chandra observations. Its X-ray spectrum is composed of both thermal and nonthermal components. The thermal component can be equally well represented by either a thin plasma model with kT = 0.19 keV or a blackbody model with kT = 0.11 keV. The nonthermal component can be fit with either a power law with Γ ∼ 1.7 or a cutoff power law with Γ ∼ 1.5 and a cutoff energy at E cut ∼ 18 keV. Using the newly obtained NuSTAR data set, we test three possible scenarios for isolated X-ray sources in the SNR–MC interaction site: (1) a pulsar wind nebula (PWN); (2) an SNR ejecta fragment; and (3) a shocked molecular clump. We conclude that this source is most likely composed of an SNR ejecta (or a PWN) and surrounding shocked molecular clumps. The nature of this hard X-ray source in the SNR–MC interaction site of IC 443 may shed light on unidentified X-ray sources with hard X-ray spectra in rich environments for star-forming regions, such as the Galactic center.

  17. X-ray spectroscopy of the mixed morphology supernova remnant W 28 with XMM-Newton

    NASA Astrophysics Data System (ADS)

    Nakamura, Ryoko; Bamba, Aya; Ishida, Manabu; Yamazaki, Ryo; Tatematsu, Ken'ichi; Kohri, Kazunori; Pühlhofer, Gerd; Wagner, Stefan J.; Sawada, Makoto

    2014-06-01

    We report on spatially resolved X-ray spectroscopy of the north-eastern part of the mixed morphology supernova remnant (SNR) W 28 with XMM-Newton. The observed field of view includes a prominent and twisted shell emission forming the edge of this SNR as well as part of the center-filled X-ray emission brightening toward the south-west edge of the field of view. The shell region spectra are in general represented by an optically thin thermal plasma emission in collisional ionization equilibrium with a temperature of ˜ 0.3 keV and a density of ˜ 10 cm-3, which is much higher than the density obtained for inner parts. In contrast, we detected no significant X-ray flux from one of the TeV γ-ray peaks with an upper-limit flux of 2.1 × 10-14 erg cm-2 s-1 in the 2-10 keV band. The large flux ratio of TeV to X-ray, larger than 16, and the spatial coincidence of the molecular cloud and the TeV γ-ray emission site indicate that the TeV γ-ray of W 28 is π0-decay emission originating from collisions between accelerated protons and molecular cloud protons. Comparing the spectrum in the TeV band and the X-ray upper limit, we obtained a weak upper limit on the magnetic field strength B ≲ 1500 μG.

  18. THE SINGLE-DEGENERATE BINARY ORIGIN OF TYCHO'S SUPERNOVA AS TRACED BY THE STRIPPED ENVELOPE OF THE COMPANION

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lu, F. J.; Ge, M. Y.; Qu, J. L.

    2011-05-01

    We propose that a nonthermal X-ray arc inside the remnant of Tycho's supernova (SN) represents the interaction between the SN ejecta and the companion star's envelope lost in the impact of the explosion. The X-ray emission of the remnant further shows an apparent shadow casted by the arc in the opposite direction of the explosion site, consistent with the blocking of the SN ejecta by the envelope. This scenario supports the single degenerate binary origin of Tycho's SN. The properties of the X-ray arc, together with the previous detection of the companion candidate and its space velocity by Ruiz-Lapuente etmore » al. and Hernandez et al., enable us to further infer that (1) the progenitor binary has a period of 4.9{sup +5.3}{sub -3.0} days, (2) the companion gained a kick velocity of 42 {+-} 30 km s{sup -1}, and (3) the stripped envelope mass is about 0.0016 ({<=}0.0083) M{sub sun}. However, we note that the nature of the companion candidate is still under debate, and the above parameters need to be revised according to the actual properties of the companion candidate. Further work to measure the proper motion of the arc and to check the capability of the interaction to emit the amount of X-rays observed from the arc is also needed to validate the current scenario.« less

  19. 84 gigahertz observations of five Crab-like supernova remnants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Salter, C. J.; Reynolds, S. P.; Hogg, D. E.

    1989-03-01

    Flux density measurements at 3.6 mm have been made to extend the frequency coverage for three Crablike remnants and two Crablike components within remnants whose large-scale morphologies show shell-type structure. All five objects show flat, polarized, nonthermal radio spectra and associated X-ray emission characteristic of this class. The flux density is found to be lower than expected on the basis of an extrapolation of the spectrum from lower frequencies. If this is due to steepening caused by evolutionary effects, severe constraints can be put on the characteristics of the objects showing spectral steepening: all must be less than 2000 yrmore » old, and the supernovae in which they were born must all have had very unusual properties. 30 refs.« less

  20. The Peculiar, Asymmetric Core-Collapse Supernova Remnant G350.1-0.3

    NASA Astrophysics Data System (ADS)

    Reynolds, Stephen

    2017-09-01

    We propose a 200 ks observation of one of the most peculiar supernova remnants known: G350.1-0.3. This mysterious object resembles no other known SNR in radio or X-rays, It contains a compact central object (CCO) which may or may not be related. Previous spectral analyses are contradictory, but there appears to be strong iron emission and an extreme overabundance of nickel. Age estimates suggest it could be as young as 600 years old. Our proposed observation should be able to measure expansion since 2009, confirming or refuting the age estimate, and will allow spectroscopy on small scales to confirm enhanced abundances and search for shocked ambient material and nonthermal emission. If the CCO originated at the remnant center, its motion will also be detected.

  1. Remnants, fuzzballs or wormholes?

    NASA Astrophysics Data System (ADS)

    Mathur, Samir D.

    2014-11-01

    The black hole information paradox has caused enormous confusion over four decades. But in recent years, the theorem of quantum strong-subadditivity has sorted out the possible resolutions into three sharp categories: (i) No new physics at r ≫ lp; this necessarily implies remnants/information loss. A realization of remnants is given by a baby universe attached near r 0. (ii) Violation of the "no-hair" theorem by nontrivial effects at the horizon r M. This possibility is realized by fuzzballs in string theory, and gives unitary evaporation. (iii) Having the vacuum at the horizon, but requiring that Hawking quanta at r M3 be somehow identified with degrees of freedom inside the black hole. A model for this "extreme nonlocality" is realized by conjecturing that wormholes connect the radiation quanta to the hole.

  2. The Fermi Gamma-Ray Space Telescope Discovers the Pulsar in the Young Galactic Supernova Remnant CTA 1

    DOE PAGES

    Abdo, A. A.; Ackermann, M.; Atwood, W. B.; ...

    2008-11-21

    Energetic young pulsars and expanding blast waves (supernova remnants, SNRs) are the most visible remains after massive stars, ending their lives, explode in core-collapse supernovae. The Fermi Gamma-Ray Space Telescope has unveiled a radio quiet pulsar located near the center of the compact synchrotron nebula inside the supernova remnant CTA 1. The pulsar, discovered through its gamma-ray pulsations, has a period of 316.86 ms, a period derivative of 3.614 x 10 -13 s s -1 . Its characteristic age of 10 4 years is comparable to that estimated for the SNR. It is conjectured that most unidentified Galactic gamma raymore » sources associated with star-forming regions and SNRs are such young pulsars.« less

  3. The Fermi Gamma Ray Space Telescope discovers the Pulsar in the Young Galactic Supernova-Remnant CTA 1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abdo, Aous A.; Ackermann, M.; Atwood, W.B.

    Energetic young pulsars and expanding blast waves (supernova remnants, SNRs) are the most visible remains after massive stars, ending their lives, explode in core-collapse supernovae. The Fermi Gamma-Ray Space Telescope has unveiled a radio quiet pulsar located near the center of the compact synchrotron nebula inside the supernova remnant CTA 1. The pulsar, discovered through its gamma-ray pulsations, has a period of 316.86 ms, a period derivative of 3.614 x 10{sup -13} s s{sup -1}. Its characteristic age of 10{sup 4} years is comparable to that estimated for the SNR. It is conjectured that most unidentified Galactic gamma ray sourcesmore » associated with star-forming regions and SNRs are such young pulsars.« less

  4. Distant Supernova Remnant Imaged by Chandra's High Resolution Camera

    NASA Astrophysics Data System (ADS)

    1999-09-01

    The High Resolution Camera (HRC), one of the two X-ray cameras on NASA's Chandra X-ray Observatory, was placed into the focus for the first time on Monday, August 30. The first target was LMC X-1, a point-like source of X rays in the Large Magellanic Cloud. The Large Magellanic Cloud, a companion galaxy to the Milky Way, is 160,000 light years from Earth. After checking the focus with LMC X-1, Chandra observed N132D, a remnant of an exploded star in the Large Magellanic Cloud. "These were preliminary test observations," emphasized Dr. Stephen Murray, of the Harvard-Smithsonian Center for Astrophysics, principal investigator for the High Resolution Camera. "But we are very pleased with the results. All indications are that the HRC will produce X-ray images of unprecedented clarity." The N132D image shows a highly structured remnant, or shell, of 10-million-degree gas that is 80 light years across. Such a shell in the vicinity of the Sun would encompass more than fifty nearby stars. The amount of material in the N132D hot gas remnant is equal to that of 600 suns. The N132D supernova remnant appears to be colliding with a giant molecular cloud, which produces the brightening on the southern rim of the remnant. The molecular cloud, visible with a radio telescope, has the mass of 300,000 suns. The relatively weak x-radiation on the upper left shows that the shock wave is expanding into a less dense region on the edge of the molecular cloud. A number of small circular structures are visible in the central regions and a hint of a large circular loop can be seen in the upper part of the remnant. Whether the peculiar shape of the supernova remnant can be fully explained in terms of these effects, or whether they point to a peculiar cylindrically shaped explosion remains to be seen. -more- "The image is so rich in structure that it will take a while to sort out what is really going on," Murray said. "It could be multiple supernovas, or absorbing clouds in the vicinity of the supernova." The unique capabilities of the HRC stem from the close match of its imaging capability to the focusing power of the mirrors. When used with the Chandra mirrors, the HRC will make images that reveal detail as small as one-half an arc second. This is equivalent to the ability to read a stop sign at a distance of twelve miles. The checkout period for the HRC will continue for the next few weeks, during which time the team expects to acquire images of other supernova remnants, star clusters, and starburst galaxies. To follow Chandra's progress, visit the Chandra News Web site at: http://chandra.harvard.edu AND http://chandra.nasa.gov NASA's Marshall Space Flight Center in Huntsville, Alabama, manages the Chandra X-ray Observatory for NASA's Office of Space Science, NASA Headquarters, Washington, D.C. The Smithsonian Astrophysical Observatory's Chandra X-ray Center in Cambridge, Mass., manages the Chandra science program and controls the observatory for NASA. TRW Space and Electronics Group of Redondo Beach, Calif., leads the contractor team that built Chandra. High resolution digital versions of the X-ray image (300 dpi JPG, TIFF) and other information associated with this release are available on the Internet at: http://chandra.harvard.edu/photo/0050/ or via links in: http://chandra.harvard.edu

  5. Radioiodine remnant ablation in differentiated thyroid cancer after combined endogenous and exogenous TSH stimulation.

    PubMed

    Vrachimis, A; Schober, O; Riemann, B

    2012-01-01

    Radioiodine remnant ablation (RRA) after (near-)total thyroidectomy (TE) is a key element in patients with differentiated thyroid cancer (DTC). The use of exogenous TSH stimulation (rhTSH) prior to RRA has shown promising results as compared to conventional thyroid hormone withdrawal (THW). As yet, the efficacy of RRA after brief THW and single rhTSH administration has not been assessed. The study sample comprised 147 patients with DTC referred to our center between May 2008 and September 2010. All patients received TE with subsequent RRA. None of these 147 patients had evidence of distant metastasis. 93 patients had endogenous TSH stimulation 4-5 weeks after surgery (group I) and twenty-six received two rhTSH injections (group II). 28 patients were treated with a single rhTSH injection after a brief THW (group III). RRA-Efficacy was assessed three months after therapy by diagnostic whole-body scan and measurement of the tumour marker thyroglobulin (Tg) under TSH stimulation. Three categories of success were defined for remnant ablation. Based on the definition of successful remnant ablation no visible uptake and a Tg ≤ 2.0 ng/ml (category 1) was seen in 62/93 patients in group I, in 17/26 patients in group II (p = n.s.) and in 12/28 patients in group III (p < 0.05). Visible radioiodine uptake and a Tg ≤ 2.0 ng/ml (category 2) was seen in 16/28 patients of group III and thus significantly more frequent than in group I (28/93 patients) (p < 0.01). However, patients in group III (16/28 patients) and group II (8/26 patients) showed no significant difference in this category (p = n.s.). Visible radioiodine uptake and a Tg > 2.0 ng/ml (category 3) was found in 3/93 patients in group I and 1/26 patients in group II but in no patient in group III. The third strategy of remnant ablation using a single injection of rhTSH after a brief THW period resulted in a significant higher rate of patients with residual uptake in the thyroid bed and a Tg level below 2 ng/ml three months after remnant ablation in comparison to THW. However, the overall efficacy of the third protocol was not significantly different as compared to two rhTSH injections. Under the aspect of the supply shortage of rhTSH the combined endogenous and exogenous TSH stimulation may be an attractive alternative for remnant ablation in differentiated thyroid cancer.

  6. Sleeve Gastrectomy: Correlation of Long-Term Results with Remnant Morphology and Eating Disorders.

    PubMed

    Tassinari, Daniele; Berta, Rossana D; Nannipieri, Monica; Giusti, Patrizia; Di Paolo, Luca; Guarino, Daniela; Anselmino, Marco

    2017-11-01

    Remnant dimension is considered one of the crucial elements determining the success of sleeve gastrectomy (SG), and dilation of the gastric fundus is often believed to be the main cause of failure. The main outcome of this study is to find correlations between remnant morphology in the immediate post-operative stage, its dilation in years, and the long-term results. The second purpose aims to correlate preoperative eating disorders, taste alteration, hunger perception, and early satiety with post-SG results. Remnant morphology was evaluated, in the immediate post-operative stage and over the years (≥2 years), through X-ray of the oesophagus-stomach-duodenum calculating the surface in anteroposterior (AP) and right anterior oblique projection (RAO). Presurgery diagnosis of eating disorders and their evaluation through "Eating Disorder Inventory-3" (EDI3) during follow-up were performed. Change in taste perception, sense of appetite, and early satiety were evaluated. Patients were divided into two groups: "failed SGs (EWL<50%) and "efficient SGs" (EWL >50%). There were a total of 50 patients (37 F, 13 M), with mean age 52 years, preoperative weight 131 ± 21.8 kg, and BMI 47.4 ± 6.8 kg/m 2 . Post-operative remnant mean dimensions overlapped between the two groups. On a long-term basis, an increase of 57.2 and 48.4% was documented in the AP and RAO areas respectively. In "failed" SGs, dilation was significantly superior to "efficient" SGs (AP area 70.2 vs 46.1%; RAO area 59.3 vs 39%; body width 102% vs 41.7%). Preoperative eating disorders were more present in efficient SGs than in failed SGs with the exception of sweet eating. There were no significant changes to taste perception during follow-up. Fifty-two percent of efficient SGs vs 26% of failed SGs reported a persistent lack of sense of hunger; similarly, 92.5 vs 78% declared the persistence of a sense of early satiety. The two groups did not statistically differ as far as all the variables of the EDI3 are concerned. On a long-term basis, the remnant mean dilation is around 50% compared to the immediate post-operative stage but failed SGs showed larger remnant dilation than efficient SGs and, in percentage, the more dilated portion is the body of the stomach. As far as all the EDI3 variables obtained are concerned, the two groups did not statistically differ. Of all eating disorders, sweet eating seems to be weakly connected to SG failure.

  7. The structure of common-envelope remnants

    NASA Astrophysics Data System (ADS)

    Hall, Philip D.

    2015-05-01

    We investigate the structure and evolution of the remnants of common-envelope evolution in binary star systems. In a common-envelope phase, two stars become engulfed in a gaseous envelope and, under the influence of drag forces, spiral to smaller separations. They may merge to form a single star or the envelope may be ejected to leave the stars in a shorter period orbit. This process explains the short orbital periods of many observed binary systems, such as cataclysmic variables and low-mass X-ray binary systems. Despite the importance of these systems, and of common-envelope evolution to their formation, it remains poorly understood. Specifically, we are unable to confidently predict the outcome of a common-envelope phase from the properties at its onset. After presenting a review of work on stellar evolution, binary systems, common-envelope evolution and the computer programs used, we describe the results of three computational projects on common-envelope evolution. Our work specifically relates to the methods and prescriptions which are used for predicting the outcome. We use the Cambridge stellar-evolution code STARS to produce detailed models of the structure and evolution of remnants of common-envelope evolution. We compare different assumptions about the uncertain end-of-common envelope structure and envelope mass of remnants which successfully eject their common envelopes. In the first project, we use detailed remnant models to investigate whether planetary nebulae are predicted after common-envelope phases initiated by low-mass red giants. We focus on the requirement that a remnant evolves rapidly enough to photoionize the nebula and compare the predictions for different ideas about the structure at the end of a common-envelope phase. We find that planetary nebulae are possible for some prescriptions for the end-of-common envelope structure. In our second contribution, we compute a large set of single-star models and fit new formulae to the core radii of evolved stars. These formulae can be used to better compute the outcome of common-envelope evolution with rapid evolution codes. We find that the new formulae are necessary for accurate predictions of the properties of post-common envelope systems. Finally, we use detailed remnant models of massive stars to investigate whether hydrogen may be retained after a common-envelope phase to the point of core-collapse and so be observable in supernovae. We find that this is possible and thus common-envelope evolution may contribute to the formation of Type IIb supernovae.

  8. Representation of the Physiological Factors Contributing to Postflight Changes in Functional Performance Using Motion Analysis Software

    NASA Technical Reports Server (NTRS)

    Parks, Kelsey

    2010-01-01

    Astronauts experience changes in multiple physiological systems due to exposure to the microgravity conditions of space flight. To understand how changes in physiological function influence functional performance, a testing procedure has been developed that evaluates both astronaut postflight functional performance and related physiological changes. Astronauts complete seven functional and physiological tests. The objective of this project is to use motion tracking and digitizing software to visually display the postflight decrement in the functional performance of the astronauts. The motion analysis software will be used to digitize astronaut data videos into stick figure videos to represent the astronauts as they perform the Functional Tasks Tests. This project will benefit NASA by allowing NASA scientists to present data of their neurological studies without revealing the identities of the astronauts.

  9. Oceanic Remnants In The Caribbean Plate: Origin And Loss Of Related LIPs.

    NASA Astrophysics Data System (ADS)

    Giunta, G.

    2005-12-01

    The modern Caribbean Plate is an independent lithospheric entity, occupying more than 4 Mkm2 and consisting of the remnants of little deformed Cretaceous oceanic plateau of the Colombia and Venezuela Basins (almost 1 Mkm2) and the Palaeozoic-Mesozoic Chortis continental block (about 700,000 km2), both bounded by deformed marginal belts. The northern (Guatemala and Greater Antilles) and the southern (northern Venezuela) plate margins are marked by collisional zones, whereas the western (Central America Isthmus) and the eastern (Lesser Antilles) margins are represented by convergent boundaries and their magmatic arcs, all involving ophiolitic terranes. The evolutionary history of the Caribbean Plate since the Jurassic-Early Cretaceous encompasses plume, accretionary, and collisional tectonics, the evidence of which has been recorded in the oceanic remnants of lost LIPs, as revealed in: i) the MORB to OIB thickened crust of the oceanic plateau, including its un-deformed or little deformed main portion, and scattered deformed tectonic units; ii) ophiolitic tectonic units of MORB affinity and the rock blocks in ophiolitic melanges; iii) intra-oceanic, supra subduction magmatic sequences with IAT and CA affinities. The Mesozoic oceanic LIPs, from which the remnants of the Caribbean Plate have been derived, have been poorly preserved during various episodes of the intra-oceanic convergence, either those related to the original proto-Caribbean oceanic realm or those connected with two eo-Caribbean stages of subduction. The trapped oceanic plateau of the Colombia and Venezuela Basins is likely to be an unknown portion of a bigger crustal element of a LIP, similar to the Ontong-Java plateau. The Jurassic-Early Cretaceous proto-Caribbean oceanic domain consists of oceanic crust generated at multiple spreading centres; during the Cretaceous, part of this crust was thickened to form an oceanic plateau with MORB and OIB affinities. At the same time, both South and North American continental margins, inferred to be close to the oceanic realm, were affected by rifting and within-plate tholeiitic magmatism (WPT); this interpretation supports a near mid-America original location of the "proto-Caribbean" LIP. The MORB magmatic sections and rock blocks in the ophiolitic melanges are interpreted as exhumed tectonic sheets of the normal proto-Caribbean oceanic lithosphere, or part of a back-arc crust, both deformed in the eo-Caribbean stages. The SSZ complexes, considered as Cordilleran-type deformed ophiolites, were derived from a LIP that experienced two superimposed eo-Caribbean stages of intra-oceanic subduction. The older (Mid-Cretaceous) stage involved the eastward subduction of the un-thickened proto-Caribbean lithosphere, resulting in IAT and CA magmatism accompanied by HP-LT metamorphism and melange formation. The second, Late Cretaceous stage involved a westward dipping intra-oceanic subduction, which generated tonalitic arc magmatism. The eastward wedging of the Caribbean Plateau between the North and South American plates progressively trapped remnants of the Colombia and Venezuela Basins between the Atlantic and Pacific subduction zones and their new volcanic arcs (Aves-Lesser Antilles and Central American Isthmus). Unlike the proto-Caribbean, it appears that this LIP did not involve the main continental margins, even though the northern and southern Caribbean borders experienced different evolutionary paths. It was largely lost by superimposed accretionary and collisional events producing the marginal belts of the Caribbean Plate; its evolution has been dominated by a strongly oblique tectonic regime, constraining seafloor spreading, subduction, crustal exhumation, emplacement, and dismembering processes.

  10. Explosive Remnants of War in Stability Operations

    DTIC Science & Technology

    2012-09-01

    strategic partner capacity building, global ERW and Counter-IED (C-IED) efforts, while adhering to global Mine /UXO awareness efforts. 15. NUMBER OF...PAGES 139 14. SUBJECT TERMS Explosive Remnants of War—Collection Point (ERW - CP), Landmine, Anti- Personnel Mine , Mine Action, Cluster Munitions...strategic partner capacity building, global ERW and Counter- IED (C-IED) efforts, while adhering to global Mine /UXO awareness efforts. vi THIS PAGE

  11. A presettlement fire history in an oak-pine forest near Basin Lake, Algonquin Park, Ontario

    Treesearch

    Richard P. Guyette; Daniel C. Dey

    1995-01-01

    Fire scars from natural remnants of red pine (Pinus resinosa Ait.) in an oak-pine forest near Basin Lake, Algonquin Park, Ontario, were dated using dendrochronological methods. A fire scar chronology was constructed from 28 dated fire scars on 26 pine remnants found in a 1 km2 area of this forest. From pith and outside ring...

  12. The Expansion and Integration of the Loanwords in the Togo Remnant Languages: An Approach Based on the Akebu Language.

    ERIC Educational Resources Information Center

    Koffi, Phil Yao

    A study suggests that the nature of linguistic borrowing in a group of 14 African languages termed Togo remnant languages--Basila, Lelemie (Buem), Aogba, Adele, Likpe, Santrokofi, Akpafu-Lolobi, Avatime, Nyangbo-Tafi, Bowili, Aklo, Kposo, Kebu, Animere--is similar to that of the Akebu language. Analysis focuses on the origins and itineraries of…

  13. Remnants of Lost Geology

    NASA Image and Video Library

    2003-02-07

    In this NASA Mars Odyssey image of eastern Arabia Terra, remnants of a once vast layered terrain are evident as isolated buttes, mesas, and deeply-filled craters. The origin of the presumed sediments that created the layers is unknown, but those same sediments, now eroded, may be the source of the thick mantle of dust that covers much of Arabia Terra today. http://photojournal.jpl.nasa.gov/catalog/PIA04400

  14. Fungus diversity in revegetated paddocks compared with remnant woodland in a south-eastern Australian agricultural landscape

    Treesearch

    Geoff Barrett; James M. Trappe; Alex Drew; Jacqui Stol; David Freudenberger

    2009-01-01

    Despite the importance of fungi for restoration, their presence in revegetated sites has received little attention. We compared the diversity and composition of macrofungi (i.e., those that form fleshy mushrooms and truffles) in 12 sites where 3- to 6-year-old native trees and shrubs had been planted (woodland restoration sites), with that in 6 woodland remnants. All...

  15. Effects on Physiology and Performance of Wearing the Aviator NBC ensemble While Flying the UH-60 Helicopter Flight Simulator in a Controlled Heat Environment.

    DTIC Science & Technology

    1992-09-01

    and collecting and processing data. They were at the front line in interacting with the subjects and maintaining morale. They did an excellent job. They...second for 16 parameter channels, and the data were processed to produce a single root mean square (RMS) error value for each channel appropriate to...represented in the final analysis. Physiological data The physiological data on the VAX were processed by sampling them at 5-minute intervals throughout the

  16. Factors affecting poor nutritional status after small bowel resection in patients with Crohn disease.

    PubMed

    Jang, Ki Ung; Yu, Chang Sik; Lim, Seok-Byung; Park, In Ja; Yoon, Yong Sik; Kim, Chan Wook; Lee, Jong Lyul; Yang, Suk-Kyun; Ye, Byong Duk; Kim, Jin Cheon

    2016-07-01

    In Crohn disease, bowel-preserving surgery is necessary to prevent short bowel syndrome due to repeated operations. This study aimed to determine the remnant small bowel length cut-off and to evaluate the clinical factors related to nutritional status after small bowel resection in Crohn disease.We included 394 patients (69.3% male) who underwent small bowel resection for Crohn disease between 1991 and 2012. Patients who were classified as underweight (body mass index < 17.5) or at high risk of nutrition-related problems (modified nutritional risk index < 83.5) were regarded as having a poor nutritional status. Preliminary remnant small bowel length cut-offs were determined using receiver operating characteristic curves. Variables associated with poor nutritional status were assessed retrospectively using Student t tests, chi-squared tests, Fisher exact tests, and logistic regression analyses.The mean follow-up period was 52.9 months and the mean patient ages at the time of the last bowel surgery and last follow-up were 31.2 and 35.7 years, respectively. The mean remnant small bowel length was 331.8 cm. Forty-three patients (10.9%) underwent ileostomy, 309 (78.4%) underwent combined small bowel and colon resection, 111 (28.2%) had currently active disease, and 105 (26.6%) underwent at least 2 operations for recurrent disease. The mean body mass index and modified nutritional risk index were 20.6 and 100.8, respectively. The independent factors affecting underweight status were remnant small bowel length ≤240 cm (odds ratio: 4.84, P < 0.001), ileostomy (odds ratio: 4.70, P < 0.001), and currently active disease (odds ratio: 4.16, P < 0.001). The independent factors affecting high nutritional risk were remnant small bowel length ≤230 cm (odds ratio: 2.84, P = 0.012), presence of ileostomy (odds ratio: 3.36, P = 0.025), and currently active disease (odds ratio: 4.90, P < 0.001).Currently active disease, ileostomy, and remnant small bowel length ≤230 cm are risk factors affecting the poor nutritional status of patients with Crohn disease after small bowel resection.

  17. The efficacy and safety of argon plasma coagulation (APC) in the management of polyp remnants in stomach and colon.

    PubMed

    Neneman, B; Gasiorowska, A; Małecka-Panas, E

    2006-01-01

    Endoscopic treatment of sessile and semipedunculated polyps remains controversial. Residual tissue remains frequently after endoscopic snare polypectomy. The aim of the study was to assess the outcome and safety of argon plasma coagulation (APC) in the management of gastric and colorectal polyp remnants after polypectomy, and to search for clinical parameters useful in predicting the efficacy of this technique. This prospective study comprised 18 patients with gastric polyps and 29 with colonic polyps found in upper and lower GI endoscopy. Overall 22 gastric polyps and 58 colonic polyps have been detected. All those polyps were removed at colonoscopy with the diathermic snare and the polyp remnants were destroyed with APC using Argon Beamer source (Erbe, Germany). Follow-up endoscopies have been performed 1, 3 and 6 months after the treatment completion. Pathologic examination revealed 10 hyperplastic polyps and 12 tubular adenomas of the stomach. Effective destruction of polyp remnants was achieved in 20 (90.9%) gastric polyps in 16 (88.9%) patients. Significant positive correlation was demonstrated between the power output, APC sessions number and polyp location in the prepyloric part, its size and adenomatous content. Among colonic polyps there were: 17 hyperplastic, 26 tubular, 8 tubulo-villous, 4 villous adenomas and 3 inflammatory pseudopolyps. Effective destruction of remnant polyp tissue was obtained in 56 (96.4%) polyps in 27 (93.1%) patients. A significant positive correlation between the power output and the size, distal location and villous texture of the polyp has been demonstrated. No complications other than mild abdominal distention have been encountered. APC is an effective and safe method in the management of polyp remnants in the stomach and colon. The application of higher electric power and numerous APC sessions are necessary to remove residues of large gastric polyps located in the prepyloric part and of with adenomatous content. In the case of colonic polyps the application of higher electric power should be recommended in case of large-sized lesions, located in rectum and of villous texture.

  18. Mesenchymal stem cells reside in anterior cruciate ligament remnants in situ.

    PubMed

    Fu, Weili; Li, Qi; Tang, Xin; Chen, Gang; Zhang, Chenghao; Li, Jian

    2016-07-01

    It has been reported that the anterior cruciate ligament (ACL) has certain self-healing ability after acute injury or with primary suture repair. Many studies have confirmed that a remnant preservation technique with ACL reconstruction contributes to biological augmentation for ACL healing. However, it remains unclear whether mesenchymal stem cells (MSC) reside in ACL remnants in situ. The aim of this study was to investigate the methods of culture and identification of MSC derived from the remnants of ACL rupture patients and to analyse these MSC's properties. The cells of ACL remnants from the ACL rupture patients were isolated by the methods of enzymatic digestion and cultured in vitro to the third passage under the microscope to observe their morphology and growth status. The third passage of isolated cells was analysed for the identification of immunophenotype, osteogenic, adipogenic and chondrogenic differentiation. On the third to fifth days of in vitro culture, a few cells of long fusiform shape appeared and were adherent to the plastic walls. On the sixth to ninth days, cells clustered and colonies were observed. The third passage cells showed uniform cell morphology and good proliferation, with appearance of the typical surface markers of MSC, CD29, CD44, CD90 and CD105. The surface markers of CD34 and CD45 of haematopoietic stem cells were not expressed. Under appropriate conditions of in vitro culture, isolated cells could be differentiated into osteoblasts that deposit mineralised matrix and express early osteogenic markers, adipocytes that accumulate lipid droplets in cytoplasm and chondrocytes that secrete chondrogenic-specific matrix aggrecan and collagen II. Real-time polymerase chain reaction (PCR) analysis demonstrated that the specific mRNA expression of osteogenesis, adipogenesis and chondrogenesis increased significantly compared with the control groups at day zero. Stem cells derived in situ from the human ACL stump were successfully isolated and characterised. Those isolated cells were identified as MSC according to their adherent ability, morphology, surface markers and multilineage differentiation potential. MSC derived from ACL remnants could be a potential source of seeding cells for ligament regeneration.

  19. Formation of S0 galaxies through mergers. Antitruncated stellar discs resulting from major mergers

    NASA Astrophysics Data System (ADS)

    Borlaff, Alejandro; Eliche-Moral, M. Carmen; Rodríguez-Pérez, Cristina; Querejeta, Miguel; Tapia, Trinidad; Pérez-González, Pablo G.; Zamorano, Jaime; Gallego, Jesús; Beckman, John

    2014-10-01

    Context. Lenticular galaxies (S0s) are more likely to host antitruncated (Type III) stellar discs than galaxies of later Hubble types. Major mergers are popularly considered too violent to make these breaks. Aims: We have investigated whether major mergers can result into S0-like remnants with realistic antitruncated stellar discs or not. Methods: We have analysed 67 relaxed S0 and E/S0 remnants resulting from dissipative N-body simulations of major mergers from the GalMer database. We have simulated realistic R-band surface brightness profiles of the remnants to identify those with antitruncated stellar discs. Their inner and outer discs and the breaks have been quantitatively characterized to compare with real data. Results: Nearly 70% of our S0-like remnants are antitruncated, meaning that major mergers that result in S0s have a high probability of producing Type III stellar discs. Our remnants lie on top of the extrapolations of the observational trends (towards brighter magnitudes and higher break radii) in several photometric diagrams, because of the higher luminosities and sizes of the simulations compared to observational samples. In scale-free photometric diagrams, simulations and observations overlap and the remnants reproduce the observational trends, so the physical mechanism after antitruncations is highly scalable. We have found novel photometric scaling relations between the characteristic parameters of the antitruncations in real S0s, which are also reproduced by our simulations. We show that the trends in all the photometric planes can be derived from three basic scaling relations that real and simulated Type III S0s fulfill: hi ∝ RbrkIII, ho ∝ RbrkIII, and μbrkIII ∝ RbrkIII, where hi and ho are the scalelengths of the inner and outer discs, and μbrkIII and RbrkIII are the surface brightness and radius of the breaks. Bars and antitruncations in real S0s are structurally unrelated phenomena according to the studied photometric planes. Conclusions: Major mergers provide a feasible mechanism to form realistic antitruncated S0 galaxies. Table 3 is available in electronic form at http://www.aanda.org

  20. Network Physiology: How Organ Systems Dynamically Interact

    PubMed Central

    Bartsch, Ronny P.; Liu, Kang K. L.; Bashan, Amir; Ivanov, Plamen Ch.

    2015-01-01

    We systematically study how diverse physiologic systems in the human organism dynamically interact and collectively behave to produce distinct physiologic states and functions. This is a fundamental question in the new interdisciplinary field of Network Physiology, and has not been previously explored. Introducing the novel concept of Time Delay Stability (TDS), we develop a computational approach to identify and quantify networks of physiologic interactions from long-term continuous, multi-channel physiological recordings. We also develop a physiologically-motivated visualization framework to map networks of dynamical organ interactions to graphical objects encoded with information about the coupling strength of network links quantified using the TDS measure. Applying a system-wide integrative approach, we identify distinct patterns in the network structure of organ interactions, as well as the frequency bands through which these interactions are mediated. We establish first maps representing physiologic organ network interactions and discover basic rules underlying the complex hierarchical reorganization in physiologic networks with transitions across physiologic states. Our findings demonstrate a direct association between network topology and physiologic function, and provide new insights into understanding how health and distinct physiologic states emerge from networked interactions among nonlinear multi-component complex systems. The presented here investigations are initial steps in building a first atlas of dynamic interactions among organ systems. PMID:26555073

  1. Passive and Active Contributions to Glenohumeral Stability

    DTIC Science & Technology

    2001-10-25

    physiological muscle contraction during free arm suspension and proportional to muscle physiological cross- sectional area [15] (Phys Load); ditto...of muscle contraction around GH-joint. Stiffness of the GH capsuloligamentous structure, which is the ratio of the force required to stretch the...important active stabilizer in inferior stability. Our results also suggested that low-level muscle activity (2% of maximum muscle contraction ), representing

  2. Comparison of remnant size in embolized intracranial aneurysms measured at follow-up with DSA and MRA.

    PubMed

    Serafin, Zbigniew; Strześniewski, Piotr; Lasek, Władysław; Beuth, Wojciech

    2012-12-01

    The possibility of recanalization and the need for retreatment are the most important limitations of intracranial aneurysm embolization. The purpose of the study was to compare the size of aneurysm remnants measured at follow-up with three-dimensional digital subtracted angiography (3D-DSA) and magnetic resonance angiography (MRA). Twenty-six aneurysms were found incompletely occluded in 72 consecutively examined patients at a follow-up after 3 months. The diameters and volume of aneurysm remnants were compared between 3D-DSA, time-of-flight MRA (TOF-MRA), contrast-enhanced TOF-MRA (CE-TOF-MRA), and contrast-enhanced MRA (CE-MRA) at 1.5 T. There was a significant correlation between remnant volumes calculated based on 3D-DSA and all MRA modalities. The intraobserver variability of the measurements ranged from 3.4 to 4.1 % and the interobserver variability from 5.8 to 7.3 %. There were no significant differences in the variability between the techniques. The mean residual filling volume ranged from 16.3 ± 19.0 mm(3) in TOF-MRA to 30.5 ± 44.6 mm(3) in 3D-DSA (P < 0.04). Significant differences were found in the volumes measured with 3D-DSA and CE-MRA as compared to TOF-MRA and CE-TOF-MRA (P < 0.01). There was a moderate significant correlation between the residual filling and the relative error of measurement in the case of TOF-MRA and CE-TOF-MRA. TOF-MRA seems to underestimate the size of aneurysm remnants detected at follow-up and should not be used as a sole imaging method to decide on re-embolization.

  3. Chinese Data of Efficacy of Low- and High-Dose Iodine-131 for the Ablation of Thyroid Remnant.

    PubMed

    Ma, Chao; Feng, Fang; Wang, Shaoyan; Fu, Hongliang; Wu, Shuqi; Ye, Zhiyi; Chen, Suyun; Wang, Hui

    2017-06-01

    Chinese data on the efficacy of low- and high-dose radioiodine for thyroid remnant are still absent. The aim of the study was to investigate whether a low dose of radioiodine is as effective as a high dose for remnant ablation in Chinese patients. Patients presenting for radioiodine ablation in the authors' department were included. Inclusion criteria were aged ≥16 years, total or near-total thyroidectomy, tumor-node-metastasis (TNM) stage of pT1-3, any N stage, and M0. All patients were randomly allocated to either the high-dose group of 3700 MBq or the low-dose group of 1850 MBq for remnant ablation. The response to treatment was defined as successful or unsuccessful after a six- to nine-month interval. Ablation was considered to be successful if patients fulfilled the following criteria: no tracer uptake in the thyroid bed on diagnosis whole-body scanning and a negative level of serum thyroglobulin. There were 327 patients enrolled between January 2013 and December 2014. More than 95% had papillary thyroid cancer. Data could be analyzed for 278 cases (M age  = 44 years; 71.6% women), 155 in the low-dose group and 123 in the high-dose group. The rate of initial successful ablation was 84.2% in all patients, 82.6% in the low-dose group, and 86.2% in the high-dose group. There was no difference between the two groups (p = 0.509). In Chinese patients with differentiated thyroid carcinoma, the low dose of 1850 MBq radioiodine activity is as effective as a high dose of 3700 MBq for thyroid remnant ablation.

  4. Former food products safety: microbiological quality and computer vision evaluation of packaging remnants contamination.

    PubMed

    Tretola, M; Di Rosa, A R; Tirloni, E; Ottoboni, M; Giromini, C; Leone, F; Bernardi, C E M; Dell'Orto, V; Chiofalo, V; Pinotti, L

    2017-08-01

    The use of alternative feed ingredients in farm animal's diets can be an interesting choice from several standpoints, including safety. In this respect, this study investigated the safety features of selected former food products (FFPs) intended for animal nutrition produced in the framework of the IZS PLV 06/14 RC project by an FFP processing plant. Six FFP samples, both mash and pelleted, were analysed for the enumeration of total viable count (TVC) (ISO 4833), Enterobacteriaceae (ISO 21528-1), Escherichia coli (ISO 16649-1), coagulase-positive Staphylococci (CPS) (ISO 6888), presumptive Bacillus cereus and its spores (ISO 7932), sulphite-reducing Clostridia (ISO 7937), yeasts and moulds (ISO 21527-1), and the presence in 25 g of Salmonella spp. (ISO 6579). On the same samples, the presence of undesired ingredients, which can be identified as remnants of packaging materials, was evaluated by two different methods: stereomicroscopy according to published methods; and stereomicroscopy coupled with a computer vision system (IRIS Visual Analyzer VA400). All FFPs analysed were safe from a microbiological point of view. TVC was limited and Salmonella was always absent. When remnants of packaging materials were considered, the contamination level was below 0.08% (w/w). Of note, packaging remnants were found mainly from the 1-mm sieve mesh fractions. Finally, the innovative computer vision system demonstrated the possibility of rapid detection for the presence of packaging remnants in FFPs when combined with a stereomicroscope. In conclusion, the FFPs analysed in the present study can be considered safe, even though some improvements in FFP processing in the feeding plant can be useful in further reducing their microbial loads and impurity.

  5. Effect of urbanization on the structure and functional traits of remnant subtropical evergreen broad-leaved forests in South China.

    PubMed

    Huang, Liujing; Chen, Hongfeng; Ren, Hai; Wang, Jun; Guo, Qinfeng

    2013-06-01

    We investigated the effects of major environmental drivers associated with urbanization on species diversity and plant functional traits (PFTs) in the remnant subtropical evergreen broad-leaved forests in Metropolitan Guangzhou (Guangdong, China). Twenty environmental factors including topography, light, and soil properties were used to quantify the effects of urbanization. Vegetation data and soil properties were collected from 30 400-m(2) plots at 6 study sites in urban and rural areas. The difference of plant species diversity and PFTs of remnant forests between urban and rural areas were analyzed. To discern the complex relationships, multivariate statistical analyses (e.g., canonical correspondence analysis and regression analysis) were employed. Pioneer species and stress-tolerant species can survive and vigorously establish their population dominance in the urban environment. The native herb diversity was lower in urban forests than in rural forests. Urban forests tend to prefer the species with Mesophanerophyte life form. In contrast, species in rural forests possessed Chamaephyte and Nanophanerophyte life forms and gravity/clonal growth dispersal mode. Soil pH and soil nutrients (K, Na, and TN) were positively related to herb diversity, while soil heavy metal concentrations (Cu) were negatively correlated with herb diversity. The herb plant species diversity declines and the species in the remnant forests usually have stress-tolerant functional traits in response to urbanization. The factors related to urbanization such as soil acidification, nutrient leaching, and heavy metal pollution were important in controlling the plant diversity in the forests along the urban-rural gradients. Urbanization affects the structure and functional traits of remnant subtropical evergreen broad-leaved forests.

  6. Double Neutron Star Mergers and Short Gamma-ray Bursts: Long-lasting High-energy Signatures and Remnant Dichotomy

    NASA Astrophysics Data System (ADS)

    Murase, Kohta; Toomey, Michael W.; Fang, Ke; Oikonomou, Foteini; Kimura, Shigeo S.; Hotokezaka, Kenta; Kashiyama, Kazumi; Ioka, Kunihito; Mészáros, Peter

    2018-02-01

    The recent detection of gravitational waves and electromagnetic counterparts from the double neutron star merger event GW+EM170817 supports the standard paradigm of short gamma-ray bursts (SGRBs) and kilonovae/macronovae. It is important to reveal the nature of the compact remnant left after the merger, either a black hole or neutron star, and their physical link to the origin of the long-lasting emission observed in SGRBs. The diversity of the merger remnants may also lead to different kinds of transients that can be detected in future. Here we study the high-energy emission from the long-lasting central engine left after the coalescence, under certain assumptions. In particular, we consider the X-ray emission from a remnant disk and the nonthermal nebular emission from disk-driven outflows or pulsar winds. We demonstrate that late-time X-ray and high-frequency radio emission can provide useful constraints on properties of the hidden compact remnants and their connections to long-lasting SGRB emission, and we discuss the detectability of nearby merger events through late-time observations at ∼30–100 days after the coalescence. We also investigate the GeV–TeV gamma-ray emission that occurs in the presence of long-lasting central engines and show the importance of external inverse Compton radiation due to upscattering of X-ray photons by relativistic electrons in the jet. We also search for high-energy gamma rays from GW170817 in the Fermi-LAT data and report upper limits on such long-lasting emission. Finally, we consider the implications of GW+EM170817 and discuss the constraints placed by X-ray and high-frequency radio observations.

  7. Mapping Calcium Rich Ejecta in Two Type Ia Supernovae

    NASA Astrophysics Data System (ADS)

    Fesen, Robert

    2016-10-01

    Type Ia supernovae (SNe Ia) are thermonuclear explosions of white dwarfs (WDs) in close binary systems with either a non-degenerate or WD companion. SN Ia explosion computations are quite challenging, involving a complex interplay of turbulent hydrodynamics, nuclear burning, conduction, radiative transfer in iron-group rich material and possibly magnetic fields leading to significant uncertainties. Several key questions about expansion asymmetries and the overall characteristics of SNe Ia could be resolved if one could obtain direct observations of the internal kinematics and elemental distributions of young SN Ia remnants.We propose to use WFC3/UVIS to obtain images of the normal Type Ia supernova remnant 0519-69.0 and the overluminous Type Ia supernova remnant 0509-67.5 in the LMC. The Ca II on-band F390M filter and off-band F336W and FQ422M filters will be used to determine the spatial extent and density distributions of the Ca-rich ejecta via resonance line absorption. Differences in the observed on and off band Ca II fluxes for LMC stars located behind these young 400 - 600 yr old remnants will yield calcium column density estimates for multiple lines-of-sight within these remnants. These results will be compared to the calcium distribution seen in SN 1885, a subluminous SN Ia in M31, already imaged by HST.The resulting calcium density distribution maps for both a normal and overluminous SN Ia events will provide powerful insights regarding the structure and kinematics of calcium-rich ejecta in three different type Ia subclass events, and unique empirical data with which to test current SN Ia explosion models.

  8. Durable Flap-Valve Mitigation of Duodenogastric Reflux,  Remnant Gastritis and Dumping Syndrome Following Billroth I Reconstruction.

    PubMed

    Hoya, Yoshiyuki; Taki, Tetsuya; Watanabe, Atsushi; Nakayoshi, Tomoko; Okamoto, Tomoyoshi; Mitsumori, Norio; Yanaga, Katsuhiko

    2016-04-01

    We have reported the short-term results of pylorus reconstruction gastrectomy (PRG) that prevents duodenogastric reflux (DGR) and remnant gastritis after distal gastrectomy. We herein report the long-term results of the PRG. PRG was performed in 37 patients (age 31 to 86 [mean 67.8 ± 12.3] years, male:female = 22:15) with gastric cancer from June 2006 through December 2013. We examined the long-term outcome in 28 patients (age 41 to 86 [mean 67.0 ± 10.7] years, male:female = 18:10) that passed over 3 years after surgery (LTR 44.1 ± 11.7 months), and compared with their short-term result after the operation (STR 13.1 ± 6.9 months). The adverse events of gastric surgery evaluated in this study consisted of the degree of remnant gastritis, the presence of dumping syndrome, and degree of weight loss (%). There was no difference in the degree of DGR and remnant gastritis by gastroscopic finding between LTR and STR after PRG (P = 0.21). Statistically, there was no difference in the bile acid concentration of remnant gastric juice between LTR and STR (108.4 ± 254.1 vs. 94.0 ± 208.6 μmol/L, P = 0.33), and weight loss of LTR was the same as that of STR (5.67 ± 7.08 vs. 4.59 ± 5.63%, P = 0.34). There were few morphological changes in the reconstructed pylorus by the long-term course, but 2 patients showed mild atrophy. The form of reconstructed pylorus and the effect that reduces side effects of Billroth I seem to last for a long time.

  9. Pyramidal lobe of the thyroid gland and the thyroglossal duct remnant: a study using human fetal sections.

    PubMed

    Takanashi, Yoshitaka; Honkura, Yohei; Rodriguez-Vazquez, Jose Francisco; Murakami, Gen; Kawase, Tetsuaki; Katori, Yukio

    2015-01-01

    To investigate developmental changes in the thyroglossal duct, we observed serial sagittal sections of eight embryos (crown-rump length (CRL) 6-12 mm; approximately 5-6 weeks of gestation) as well as serial horizontal or cross-sections of 70 embryos and fetuses (CRL 15-110 mm; 6-15 weeks). In the sagittal sections, the thyroglossal duct was identified as a small sheet or mass of relatively large cells with vacuolization anterior, superior or inferior to the fourth pharyngeal arch artery. However, we found no continuous duct-like structure that reached the thyroid gland. Thus, previous classical schemes might have overestimated the continuity of the duct. Among cross-sections of 70 specimens, we found the thyroglossal duct remnant in only two specimens (CRL 15 mm and 100 mm), in contrast to the pyramidal lobe, which was seen in one-third of the specimens. The duct remnant ran downward along the lateral edge of the hyoid body to reach the anterior aspect of the thyroid cartilage. However, the connection between the pyramidal lobe and the duct remnant was interrupted by the anterior cervical muscles. Therefore, it was unlikely that the thyroglossal duct remnant would more frequently be evident in fetuses than in adults. The highly tortuous course of the duct along the lingual aspect of the hyoid body, which has been reported previously, appeared to become established near term. Descent of the thyroid gland was not evident after the CRL 20 mm stage (6 weeks): the gland appeared to retain its position at the level of the third-sixth cervical vertebrae. Copyright © 2014 Elsevier GmbH. All rights reserved.

  10. A Novel Selective PPARα Modulator (SPPARMα), K-877 (Pemafibrate), Attenuates Postprandial Hypertriglyceridemia in Mice.

    PubMed

    Sairyo, Masami; Kobayashi, Takuya; Masuda, Daisaku; Kanno, Koutaro; Zhu, Yinghong; Okada, Takeshi; Koseki, Masahiro; Ohama, Tohru; Nishida, Makoto; Sakata, Yasushi; Yamashita, Shizuya

    2018-02-01

    Fasting and postprandial hypertriglyceridemia (PHTG) are caused by the accumulation of triglyceride (TG)-rich lipoproteins and their remnants, which have atherogenic effects. Fibrates can improve fasting and PHTG; however, reduction of remnants is clinically needed to improve health outcomes. In the current study, we investigated the effects of a novel selective peroxisome proliferator-activated receptor α modulator (SPPARMα), K-877 (Pemafibrate), on PHTG and remnant metabolism. Male C57BL/6J mice were fed a high-fat diet (HFD) only, or an HFD containing 0.0005% K-877 or 0.05% fenofibrate, from 8 to 12 weeks of age. After 4 weeks of feeding, we measured plasma levels of TG, free fatty acids (FFA), total cholesterol (TC), HDL-C, and apolipoprotein (apo) B-48/B-100 during fasting and after oral fat loading (OFL). Plasma lipoprotein profiles after OFL, which were assessed by high performance liquid chromatography (HPLC), and fasting lipoprotein lipase (LPL) activity were compared among the groups. Both K-877 and fenofibrate suppressed body weight gain and fasting and postprandial TG levels and enhanced LPL activity in mice fed an HFD. As determined by HPLC, K-877 and fenofibrate significantly decreased the abundance of TG-rich lipoproteins, including remnants, in postprandial plasma. Both K-877 and fenofibrate decreased intestinal mRNA expression of ApoB and Npc1l1; however, hepatic expression of Srebp1c and Mttp was increased by fenofibrate but not by K-877.Hepatic mRNA expression of apoC-3 was decreased by K-877 but not by fenofibrate. K-877 may attenuate PHTG by suppressing the postprandial increase of chylomicrons and the accumulation of chylomicron remnants more effectively than fenofibrate.

  11. A Year in the Life of an Infrared Echo

    NASA Technical Reports Server (NTRS)

    2005-01-01

    [figure removed for brevity, see original site] Figure 1: Supernova Remnant Cassiopeia A One Year Apart

    These Spitzer Space Telescope images, taken one year apart, show the supernova remnant Cassiopeia A (yellow ball) and surrounding clouds of dust (reddish orange). The pictures illustrate that a blast of light from Cassiopeia A is waltzing outward through the dusty skies. This dance, called an 'infrared echo,' began when the remnant erupted about 50 years ago.

    Cassiopeia A is the remnant of a once massive star that died in a violent supernova explosion 325 years ago. It consists of a dead star, called a neutron star, and a surrounding shell of material that was blasted off as the star died. This remnant is located 10,000 light-years away in the northern constellation Cassiopeia.

    Infrared echoes are created when a star explodes or erupts, flashing light into surrounding clumps of dust. As the light zips through the dust clumps, it heats them up, causing them to glow successively in infrared, like a chain of Christmas bulbs lighting up one by one. The result is an optical illusion, in which the dust appears to be flying outward at the speed of light. Echoes are distinct from supernova shockwaves, which are made up material that is swept up and hurled outward by exploding stars.

    This infrared echo is the largest ever seen, stretching more than 50 light-years away from Cassiopeia A. If viewed from Earth, the entire movie frame would take up the same amount of space as two full moons.

    Hints of an older infrared echo from Cassiopeia A's supernova explosion hundreds of years ago can also be seen.

    The top Spitzer image was taken on November 30, 2003, and the bottom, on December 2, 2004.

  12. Double-bundle anterior cruciate ligament reconstruction with and without remnant preservation - Comparison of early postoperative outcomes and complications.

    PubMed

    Nakayama, Hiroshi; Kambara, Syunichiro; Iseki, Tomoya; Kanto, Ryo; Kurosaka, Kenji; Yoshiya, Shinichi

    2017-10-01

    To compare the early postoperative outcomes and complications of double-bundle anterior cruciate ligament (ACL) reconstruction with and without remnant preservation. The study population comprised 125 consecutive knees that underwent double-bundle ACL reconstruction using hamstring autograft. Among the 125 knees, remnant preservation was indicated for 50 knees, while standard double-bundle reconstruction was performed in the remaining 75 knees. Postoperative evaluations included heel-height difference (HHD) at periodical follow-ups, number of knees requiring arthroscopic debridement due to problematic extension loss within six months, re-injury within one year, graft status upon second-look arthroscopy, and clinical examinations by Lysholm score and KT measurement at one year. All patients could be followed up for a minimum of one year after surgery. When the results obtained from both groups were compared, HHD values were significantly larger in the preservation group at three and six months, and the rate of knees requiring arthroscopic debridement was also higher in this group (12% versus 4.0%). Graft status on second-look arthroscopy was considered to be good for 92% of the knees in the preservation group versus 59% in the non-preservation group. Re-injury rates within one year were 2.0% in the preservation group and 5.3% in the non-preservation group. No significant differences in clinical examinations were found between the groups at one year. Remnant preservation in double-bundle hamstring autograft ACL reconstruction may enhance tissue healing; however, retention of the remnant with its full volume resulted in an increased incidence of postoperative problematic extension loss. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. A morphologic and quantitative comparison of mechanoreceptors in the tibial remnants of the ruptured human anterior cruciate ligament.

    PubMed

    Sha, Lin; Xie, Guoming; Zhao, Song; Zhao, Jinzhong

    2017-02-01

    Reconstruction of the ruptured anterior cruciate ligament (ACL) does not always result in expected successful outcome. A satisfactory outcome depends not only on the tightness or strength of the graft but also on the quality of proprioceptive restoration. Mechanoreceptors of ACL are supposed to play considerable roles in the proprioceptive feedback system of knee. This study aimed to observe the condition and number of the surviving mechanoreceptors in the tibial remnant of ruptured ACL in human knees.From April 2009 to January 2012, 60 patients with existing free tibial remnants who had undergone arthroscopic ACL reconstruction were enrolled and divided into 4 groups according to the time duration of injury to surgery (Group I: no more than 3 months; Group II: 3 to 6 months; Group III, 6 months to 1 year; Group IV: more than 1 year). Six normal ACL specimens were taken as controls. Specimens were obtained from ACL tibial remnant and stained by the immunohistochemical staining method. The type, size, and quantity of mechanoreceptors were observed under the light microscope. A total of 92 Ruffini-like corpuscles, 9 Pacini-like corpuscles, 5 unclassified neural endings, and free nerve endings were identified via immunohistochemical staining.There were no significant differences in the number of mechanoreceptors in the 5 groups (P = 0.238). Some degenerative changes were observed in Group IV. The results suggest that the residual mechanoreceptors in the ruptured ACL exhibit long-term survival and showed no obvious signs of withering within 1 year.Residual mechanoreceptors do exist in the tibial remnants of ruptured anterior cruciate ligament in human knees and identified clearly by using immunohistochemistry staining. No significant difference was found regarding quantitative variation of the residual mechanoreceptors about the injury duration.

  14. Tree and stand transpiration in a Midwestern bur oak savanna after elm encroachment and restoration thinning

    USGS Publications Warehouse

    Asbjornsen, H.; Tomer, M.D.; Gomez-Cardenas, M.; Brudvig, L.A.; Greenan, C.M.; Schilling, K.

    2007-01-01

    Oak savannas, once common in the Midwest, are now isolated remnants within agricultural landscapes. Savanna remnants are frequently encroached by invasive trees to become woodlands. Thinning and prescribed burning can restore savanna structure, but the ecohydrological effects of managing these remnants are poorly understood. In this study, we measured sap flow (Js) to quantify transpiration in an Iowa bur oak (Quercus macrocarpa) savanna woodland encroached by elms (Ulmus americana), and in an adjacent restored savanna after thinning to remove elms, during summer 2004. Savanna oaks had greater mean daily Js (35.9 L dm-2 day-1) than woodland oaks (20.7 L dm-2 day-1) and elms (12.4 L dm-2 day-1). The response of Js to vapor pressure deficit (D) was unexpectedly weak, although oaks in both stands showed negative correlation between daily Js and D for D > 0.4 kPa. An earlier daily peak in Js in the elm trees showed a possible advantage for water uptake. As anticipated, the woodland's stand transpiration was greater (1.23 mm day-1) than the savanna's (0.35 mm day-1), yet the savanna achieved 30% of the woodland's transpiration with only 11% of its sapwood area. The difference in transpiration influenced water table depths, which were 2 m in the savanna and 6.5 m in the woodland. Regionally, row-crop agriculture has increased groundwater recharge and raised water tables, providing surplus water that perhaps facilitated elm encroachment. This has implications for restoration of savanna remnants. If achieving a savanna ecohydrology is an aim of restoration, then restoration strategies may require buffers, or targeting of large or hydrologically isolated remnants. ?? 2007.

  15. Neutron Star/supernova Remnant Associations

    NASA Astrophysics Data System (ADS)

    Gvaramadze, V. V.

    We propose a new approach for studying the neutron star/supernova remnant associations, based on the idea that the (diffuse) supernova remnants (SNRs) can be products of an off-centred supernova (SN) explosion in a preexisting bubble created by the wind of a moving massive star. A cavity SN explosion of a moving star results in a considerable offset of the neutron star (NS) birth-place from the geometrical centre of the SNR. Therefore: a) the high transverse velocities inferred for a number of NSs (e.g. PSR B 1610-50, PSR B 1757-24, SGR 0525-66) through their association with SNRs can be reduced; b) the proper motion vector of a NS should not necessarily point away from the geometrical centre of the associated SNR. Taking into account of these two facts allow us to enlarge the circle of possible NS/SNR associations, and could significantly affect the results of previous studies of NS/SNR associations. The possibilities of our approach are illustrated with the example of the association between PSR B 1706-44 and SNR G 343.1-2.3. We show that this association could be real if both objects are the remnants of a SN exploded within a mushroom-like cavity (created by the SN progenitor wind breaking out of the parent molecular cloud and expanding into an intercloud medium of a much less density). We also show that the SN explosion sites in some middle-aged (shell-like) SNRs could be marked by (compact) nebulae of thermal X-ray emission. The possible detection of such nebulae within middle-aged SNRs could be used for the re-estimation of implied transverse velocities of known NSs or for the search of new stellar remnants possibly associated with these SNRs.

  16. Multi-dimensional simulations of the expanding supernova remnant of SN 1987A

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Potter, T. M.; Staveley-Smith, L.; Reville, B.

    The expanding remnant from SN 1987A is an excellent laboratory for investigating the physics of supernovae explosions. There is still a large number of outstanding questions, such as the reason for the asymmetric radio morphology, the structure of the pre-supernova environment, and the efficiency of particle acceleration at the supernova shock. We explore these questions using three-dimensional simulations of the expanding remnant between days 820 and 10,000 after the supernova. We combine a hydrodynamical simulation with semi-analytic treatments of diffusive shock acceleration and magnetic field amplification to derive radio emission as part of an inverse problem. Simulations show that anmore » asymmetric explosion, combined with magnetic field amplification at the expanding shock, is able to replicate the persistent one-sided radio morphology of the remnant. We use an asymmetric Truelove and McKee progenitor with an envelope mass of 10 M {sub ☉} and an energy of 1.5 × 10{sup 44} J. A termination shock in the progenitor's stellar wind at a distance of 0.''43-0.''51 provides a good fit to the turn on of radio emission around day 1200. For the H II region, a minimum distance of 0.''63 ± 0.''01 and maximum particle number density of (7.11 ± 1.78) × 10{sup 7} m{sup –3} produces a good fit to the evolving average radius and velocity of the expanding shocks from day 2000 to day 7000 after explosion. The model predicts a noticeable reduction, and possibly a temporary reversal, in the asymmetric radio morphology of the remnant after day 7000, when the forward shock left the eastern lobe of the equatorial ring.« less

  17. Unveiling the spatial structure of the overionized plasma in the supernova remnant W49B

    NASA Astrophysics Data System (ADS)

    Zhou, Xin; Miceli, Marco; Bocchino, Fabrizio; Orlando, Salvatore; Chen, Yang

    2011-07-01

    W49B is a mixed-morphology supernova remnant with thermal X-ray emission dominated by the ejecta. In this remnant, the presence of overionized plasma has been directly established, with information about its spatial structure. However, the physical origin of the overionized plasma in W49B has not yet been understood. We investigate this intriguing issue through a 2D hydrodynamic model that takes into account, for the first time, the mixing of ejecta with the inhomogeneous circumstellar and interstellar medium, the thermal conduction, the radiative losses from optically thin plasma and the deviations from equilibrium of ionization induced by plasma dynamics. The model was set up on the basis of the observational results. We found that the thermal conduction plays an important role in the evolution of W49B, inducing the evaporation of the circumstellar ring-like cloud (whose presence has been deduced from previous observations) that mingles with the surrounding hot medium, cooling down the shocked plasma, and pushes the ejecta backwards to the centre of the remnant, forming there a jet-like structure. During the evolution, a large region of overionized plasma forms within the remnant. The overionized plasma originates from the rapid cooling of the hot plasma originally heated by the shock reflected from the dense ring-like cloud. In particular, we found two different ways for the rapid cooling of plasma to appear: (i) the mixing of relatively cold and dense material evaporated from the ring with the hot shocked plasma and (ii) the rapid adiabatic expansion of the ejecta. The spatial distribution of the radiative recombination continuum predicted by the numerical model is in good agreement with that observed.

  18. Plasticity of brain wave network interactions and evolution across physiologic states

    PubMed Central

    Liu, Kang K. L.; Bartsch, Ronny P.; Lin, Aijing; Mantegna, Rosario N.; Ivanov, Plamen Ch.

    2015-01-01

    Neural plasticity transcends a range of spatio-temporal scales and serves as the basis of various brain activities and physiologic functions. At the microscopic level, it enables the emergence of brain waves with complex temporal dynamics. At the macroscopic level, presence and dominance of specific brain waves is associated with important brain functions. The role of neural plasticity at different levels in generating distinct brain rhythms and how brain rhythms communicate with each other across brain areas to generate physiologic states and functions remains not understood. Here we perform an empirical exploration of neural plasticity at the level of brain wave network interactions representing dynamical communications within and between different brain areas in the frequency domain. We introduce the concept of time delay stability (TDS) to quantify coordinated bursts in the activity of brain waves, and we employ a system-wide Network Physiology integrative approach to probe the network of coordinated brain wave activations and its evolution across physiologic states. We find an association between network structure and physiologic states. We uncover a hierarchical reorganization in the brain wave networks in response to changes in physiologic state, indicating new aspects of neural plasticity at the integrated level. Globally, we find that the entire brain network undergoes a pronounced transition from low connectivity in Deep Sleep and REM to high connectivity in Light Sleep and Wake. In contrast, we find that locally, different brain areas exhibit different network dynamics of brain wave interactions to achieve differentiation in function during different sleep stages. Moreover, our analyses indicate that plasticity also emerges in frequency-specific networks, which represent interactions across brain locations mediated through a specific frequency band. Comparing frequency-specific networks within the same physiologic state we find very different degree of network connectivity and link strength, while at the same time each frequency-specific network is characterized by a different signature pattern of sleep-stage stratification, reflecting a remarkable flexibility in response to change in physiologic state. These new aspects of neural plasticity demonstrate that in addition to dominant brain waves, the network of brain wave interactions is a previously unrecognized hallmark of physiologic state and function. PMID:26578891

  19. HI Absorption in Merger Remnants

    NASA Technical Reports Server (NTRS)

    Teng, Stacy H.; Veileux, Sylvain; Baker, Andrew J.

    2012-01-01

    It has been proposed that ultraluminous infrared galaxies (ULIRGs) pass through a luminous starburst phase, followed by a dust-enshrouded AGN phase, and finally evolve into optically bright "naked" quasars once they shed their gas/dust reservoirs through powerful wind events. We present the results of our recent 21- cm HI survey of 21 merger remnants with the Green Bank Telescope. These remnants were selected from the QUEST (Quasar/ULIRG Evolution Study) sample of ULIRGs and PG quasars; our targets are all bolometrically dominated by AGN and sample all phases of the proposed ULIRG -> IR-excess quasar -> optical quasar sequence. We explore whether there is an evolutionary connection between ULIRGs and quasars by looking for the occurrence of HI absorption tracing neutral gas outflows; our results will allow us to identify where along the sequence the majority of a merger's gas reservoir is expelled.

  20. Identifying the TeV gamma-ray source MGRO J2228+61, FINALLY!

    NASA Astrophysics Data System (ADS)

    Aliu, Ester

    2012-09-01

    New VERITAS observations of MGRO J2228+61 allow us to associate its TeV emission with the enigmatic radio supernova remnant SNR G106.3+2.7. This remnant is part of a large complex that includes the Boomerang pulsar and nebula. The reduced field suggests that the TeV emission is not powered by the Boomerang, but instead associated with a much larger remnant. A recent SUZAKU X-ray observation of the smaller gamma-ray error box reveals two possible pulsar candidates. We propose short ACIS exposures to identify these sources to determine if one or both can be responsible for the gamma-ray emission. This will allow us to address the long standing problem on the nature of both MGRO J2228+61 and SNR G106.3+2.7.

  1. High resolution observations of Cassiopeia A at meter wavelengths. [pulsar source in supernova remnant

    NASA Technical Reports Server (NTRS)

    Hutton, L. K.; Clark, T. A.; Erickson, W. C.; Resch, G. M.; Vandenberg, N. R.; Knowles, S. H.; Youmans, A. B.

    1974-01-01

    Very long baseline interferometric (VLBI) observations of the supernova remnant Cassiopeia A, at 74 MHz with a 12,000-wavelength baseline and at 111 MHz with a 18,500-wavelength baseline, are reported. The fringe amplitudes are strongly varying on a time scale of about 15 to 30 minutes. The location of the extra source must lie outside the supernova remnant shell possibly associated with a concentration of emission north of the shell, or lying outside the gap in the northeastern side of the shell. The flux and spectral index deduced for the compact source depend on the assumed size, with a range of 100 Jy to 500 Jy at 74 MHz. If the source is associated with the supernova explosion, it must have been traveling at least 5000 km s/2.

  2. Fermi Large Area Telescope Detection Of The Young Supernova Remnant Tycho

    DOE PAGES

    Giordano, F.; Naumann-Godo, M.; Ballet, J.; ...

    2011-12-07

    After almost three years of data taking in sky survey mode, the Fermi -LAT has detected γ-ray emission toward the Tycho’s Supernova Remnant (SNR). The Tycho SNR is among the youngest remnants in the Galaxy, originating from a Type Ia Supernova in AD 1572. The γ-ray integral flux from 400 MeV up to 100 GeV has been measured to be (3.5±1.1stat±0.7syst)×10 -9 cm -2s -1 with a photon index of 2.3±0.2stat±0.1syst. A simple model consistent with TeV, X-ray and radio data is sufficient to explain the observed emission as originating from π 0-decays as a result of cosmicray acceleration andmore » interaction with the ambient medium.« less

  3. Five years of change in an old-growth pine-hardwood remnant in Ashley County, Arkansas

    Treesearch

    Don C. Bragg

    2006-01-01

    The Levi Wilcoxon Demonstration Forest near Hamburg, Arkansas is an industrially-owned remnant of old-growth pine and hardwoods. Some of the loblolly (Pinus taeda L.) and shortleaf (Pinus echinata Mill.) pine in this stand are over 200 years old, and numerous individuals exceed 90 cm in diameter and 30 m in height. A 2000 survey of a portion of this...

  4. Cutaneous remnants of the vitellointestinal duct: a clinico-pathological study of 19 cases

    PubMed Central

    Heatley, M K; Mirakhur, M

    1988-01-01

    The presence of cutaneous vitellointestinal duct remnants was confirmed histologically in 19 cases in the period 1970-1984. These lesions occurred mostly in males (16 males, 3 females), and 80% in children under the age of five years. One case was identified in an adult, suggesting that these lesions may in some cases cause little inconvenience, and that their true incidence is underestimated. PMID:3266043

  5. Effectiveness of a decontamination method for donor corneas.

    PubMed

    Badenoch, P R; Alfrich, S J; Wedding, T R; Coster, D J

    1988-03-01

    A retrospective study was made of the effectiveness of an eye bank decontamination and storage method. A comparison was made between microbial cultures taken from the limbus at enucleation and from scleral remnants recovered after surgery. Organisms were isolated from the limbus of 73% of donor eyes and from 4% of remnants. Standard eye bank procedures were found to eradicate gut and skin organisms, including candida, from donor tissue.

  6. On the velocity of the Vela pulsar

    NASA Astrophysics Data System (ADS)

    Gvaramadze, V.

    2001-04-01

    It is shown that if the shell of the Vela supernova remnant is responsible for nearly all the scattering of the Vela pulsar, then the scintillation and proper motion velocities of the pulsar can only be reconciled with each other in the case of nonzero transverse velocity of the scattering material. A possible origin of large-scale transverse motions in the shell of the Vela supernova remnant is discussed.

  7. Does fingerprinting truly represent the diversity of wine yeasts? A case study with interdelta genotyping of Saccharomyces cerevisiae strains.

    PubMed

    Pfliegler, W P; Sipiczki, M

    2016-12-01

    Simple and efficient genotyping methods are widely used to assess the diversity of a large number of microbial strains, e.g. wine yeasts isolated from a specific geographical area or a vintage. Such methods are often also the first to be applied, to decrease the number of strains deemed interesting for a more time-consuming physiological characterization. Here, we aimed to use a physiologically characterized strain collection of 69 Saccharomyces cerevisiae strains from Hungarian wine regions to determine whether geographical origin or physiological similarity can be recovered by clustering the strains with one or two simultaneously used variations of interdelta genotyping. Our results indicate that although a detailed clustering with high resolution can be achieved with this method, the clustering of strains is largely contrasting when different primer sets are used and it does not recover geographical or physiological groups. Genotyping is routinely used for assessing the diversity of a large number of isolates/strains of a single species, e.g. a collection of wine yeasts. We tested the efficiency of interdelta genotyping on a collection of Saccharomyces wine yeasts from four wine regions of Hungary that was previously characterized physiologically. Interdelta fingerprinting recovered neither physiological nor geographical similarities, and in addition, the two different primer pairs widely used for this method showed conflicting and barely comparable results. Thus, this method does not necessarily represent the true diversity of a strain collection, but detailed clustering may be achieved by the combined use of primer sets. © 2016 The Society for Applied Microbiology.

  8. Premium campground with lake view - pingo remnants as preferred Mesolithic settlement sites?

    NASA Astrophysics Data System (ADS)

    Hüser, Andreas; Enters, Dirk; Wolters, Steffen

    2016-04-01

    Pingo remnants are typical but not always easily visible landscape features in northwestern Germany and the Netherlands. Some of them are still small lakes but present-day land-use mostly disguises the existence of formerly water-filled depressions. In addition the circular wall structures have often been leveled by agricultural activities in modern times. However, according to estimates several hundreds pingo remnants bearing witness to Weichselian periglacial conditions can still be found in East Frisia and in the area between the rivers Elbe and Weser. Preliminary paleoecological investigations have shown that the majority of them were water-filled until Neolithic times making them a potential campground of preference for the Mesolithic population. In addition to wind shelter behind wall structures or dunes, Mesolithic hunter-gatherer communities could have used here both aquatic and terrestrial food resources. We investigated three of these pingo remnants in northwestern Germany using a multi-proxy approach combining an iterative archaeological site analysis with sediment core studies including geochemical and biological proxies. Our results show that Mesolithic artifacts are often concentrated close to open water bodies. The sediment cores obtained cover the time span from the late Palaeolithic to modern times. Excellent preservation conditions and a moderate sedimentation rate during the Mesolithic enables environmental change to be reconstructed.

  9. Long-term follow-up of nutritional status, pancreatic function, and morphological changes of the pancreatic remnant after pancreatic tumor resection in children.

    PubMed

    Sugito, Kiminobu; Furuya, Takeshi; Kaneda, Hide; Masuko, Takayuki; Ohashi, Kensuke; Inoue, Mikiya; Ikeda, Taro; Koshinaga, Tsugumichi; Tomita, Ryouichi; Maebayashi, Toshiya

    2012-05-01

    The objectives of the present study were to determine nutritional status, pancreatic function, and morphological changes of the pancreatic remnant after pancreatic tumor resection in children. The nutritional status was evaluated by the patterns of growth. Pancreatic function was evaluated by using a questionnaire, the Bristol stool form chart, the serum levels of fasting blood glucose, and hemoglobin A1c (HbA1c). Morphological changes of the pancreatic remnant were evaluated by computed tomography, magnetic resonance image, or magnetic resonance cholangiopancreatography. The present study consisted of 6 patients with pancreatic tumor (5 solid pseudopapillary tumors of the pancreas and 1 pancreatoblastoma) who underwent the following operations: tumor enucleation (3), distal pancreatectomy with splenectomy (1), and pylorus-preserving pancreatoduodenectomy (PPPD [2]). The serum levels of HbA1c have been gradually elevated in 2 patients with PPPD. A significant decrease in pancreatic parenchymal thickness and dilatation of the main pancreatic duct were observed in 2 patients with PPPD. Endocrine pancreatic insufficiency after PPPD may be explainable by obstructive pancreatitis after operation. Taking together the results of pancreatic endocrine function and morphological changes of pancreatic remnant after PPPD, tumor enucleation should be considered as surgical approach in children with pancreas head tumor whenever possible.

  10. Surface debris of canal walls after post space preparation in endodontically treated teeth: a scanning electron microscopic study.

    PubMed

    Serafino, Cinzia; Gallina, Giuseppe; Cumbo, Enzo; Ferrari, Marco

    2004-03-01

    To evaluate surface cleanliness of root canal walls along post space after endodontic treatment using 2 different irrigant regimens, obturation techniques, and post space preparation for adhesive bonding. Forty teeth, divided into 4 groups, were instrumented, using Ni-Ti rotary files, irrigated with NaOCl or NaOCl+EDTA and obturated with cold lateral condensation (CLC) or warm vertical condensation (WVC) of gutta-percha. After post space preparation, etching, and washing procedure, canal walls were observed using a scanning electron microscope (SEM). Amount of debris, smear layer, sealer/gutta-percha remnants, and visibility of open tubules were rated. Higher amounts of rough debris, large sealer/gutta-percha remnants, thick smear layer, and no visibility of tubule orifices were recorded in all the groups at apical level of post space. At middle and coronal levels areas of clean dentin, alternating with areas covered by thin smear layer, smaller debris, gutta-percha remnants, and orifices of tubules partially or totally occluded by plugs were frequently observed. After endodontic treatment, obturation, and post space preparation SEM analysis of canal walls along post space shows large areas (covered by smear layer, debris, and sealer/gutta-percha remnants) not available for adhesive bonding and resin cementation of fiber posts.

  11. An ASCA Study of the Composite Supernova Remnant G18.95-1.1

    NASA Technical Reports Server (NTRS)

    Harrus, Ilana

    2000-01-01

    This is the final report on the work done on Supernova Remnant (SNR) G18-95-1.1. The data were taken on April, 2. 1998 and delivered a couple of months later to the Principal Investigator (PI: Dr. Ilana Harrus). We received a CD-ROM containing the results of the standard processing pipeline and all the files needed for the analysis. We have analyzed the data and presented a poster on this object at the 194th American Astronomical Society Meeting in Chicago (June 1999). A copy of the poster is appended to this report. The poster presentation triggered several discussions and we are summarizing the analysis results and those discussions in a paper to be submitted soon to the Astrophysical Journal. We have appended the draft of the paper to this report. It must be noted that the paper is still in its early stages. In particular more work is needed in the physical implications of the results of the spectral analysis and in the comparison with theoretical models to understand the curious morphology of the remnant. The project should be completed within the next two months. Attachment: "ASCA study of the centrally-peaked thermal supernova remnant: G18.95-1.1".

  12. The supernova - supernova remnant connection through multi-dimensional magnetohydrodynamic modeling

    NASA Astrophysics Data System (ADS)

    Orlando, S.; Miceli, M.; Petruk, O.; Ono, M.

    2017-10-01

    Supernova remnants (SNRs) are diffuse extended sources often characterized by a rather complex morphology and a highly non-uniform distribution of ejecta. General consensus is that such a morphology reflects, on one hand, pristine structures and features of the progenitor supernova (SN) explosion and, on the other hand, the early interaction of the SN blast wave with the inhomogeneous circumstellar medium (CSM) formed in the latest stages of the progenitor star's evolution. Deciphering X-ray observations of SNRs, therefore, might open the possibility to reconstruct the ejecta structure as it was soon after the SN explosion and the structure and geometry of the medium immediately surrounding the progenitor star. This requires accurate and detailed models which describe the evolution from the on-set of the SN to the full remnant development and which connect the X-ray emission properties of the remnants to the progenitor SNe. Here we show how multi-dimensional SN-SNR magnetohydrodynamic models have been very effective in deciphering X-ray observations of SNR Cassiopeia A and SN 1987A. This has allowed us to unveil the average structure of ejecta in the immediate aftermath of the SN explosion and to constrain the 3D pre-supernova structure and geometry of the environment surrounding the progenitor SN.

  13. Supernova remnants in the GC region

    NASA Astrophysics Data System (ADS)

    Asvarov, Abdul

    2016-07-01

    Along with the central Black hole the processes of active star formation play very important role in the energetics of the Galactic center region. The SNe and their remnants (SNRs) are the main ingredients of the processes of star formation. SNRs are also the sources of electromagnetic radiation of all wavelengths from the optical to hard gamma rays. In the presented work we consider the physics of supernova remnants evolving in extreme environmental conditions which are typical for the region of the Galactic center. Because of the high density and strong inhomogeneity of the surrounding medium these objects remain practically invisible at almost all wavelengths. We model evolution of SNR taking into account the pressure of the surrounding medium and the gravitational field of the matter (stars, compact clouds, dark matter) inside the remnant. As it is well established, considerable portion of the kinetic energy of the SNR can be converted into the cosmic ray particles by diffusive shock acceleration mechanism. Therefore the effect of particle acceleration is also included in the model (with the effectiveness of acceleration as a free parameter). Using the observed radiation fluxes at different wavelengths we attempt to obtain limits on the parameters of the model of the Galactic Center, namely, the frequency of star birth, the average density of the matter and radiation field, etc.

  14. Search for Nonthermal X-Rays from Supernova Remnant Shells

    NASA Astrophysics Data System (ADS)

    Petre, R.; Keohane, J.; Hwang, U.; Allen, G.; Gotthelf, E.

    The demonstration by ASCA that the nonthermal X-ray emission from the rim of SN1006 is synchrotron emission from TeV electrons, produced in the same environment responsible for cosmic ray protons and nuclei (Koyama et al. 1995, Nature 378, 255), has stimulated a search for nonthermal X-rays from other remnants. Nonthermal emission has subsequently been found to arise in the shells of at least two other remnants, Cas A and IC 443. In Cas A, a hard tail is detected using ASCA, XTE, and OSSE to energies exceeding 100 keV; the shape of the spectrum rules out all mechanisms except synchrotron radiation. In IC 443, the previously known hard emission has been shown using ASCA to be isolated to a small region along the rim of the remnant, where the shock is interacting most strongly with a molecular cloud. Nonthermal X-ray emission is thought to arise here by enhanced cosmic ray production associated with the shock/cloud interaction (Keohane et al. 1997, ApJ in press). We describe the properties of the nonthermal emission in SN1006, Cas A, and IC 443, and discuss the status of our search for nonthermal emission associated with the shocks of other Galactic and LMC SNR's.

  15. Urban Rights-of-Way as Reservoirs for Tall-Grass Prairie Plants and Butterflies.

    PubMed

    Leston, Lionel; Koper, Nicola

    2016-03-01

    Urban rights-of-way may be potential reservoirs of tall-grass prairie plants and butterflies. To determine if this is true, in 2007-2008, we conducted vegetation surveys of species richness and cover, and butterfly surveys of species richness and abundance, along 52 transmission lines and four remnant prairies in Winnipeg, Manitoba. We detected many prairie plants and butterflies within transmission lines. Some unmowed and infrequently managed transmission lines had native plant species richness and total percent cover of native plants comparable to that of similar-sized remnant tall-grass prairies in the region. Although we did not find significant differences in overall native butterfly numbers or species richness between rights-of-way and remnant prairies, we found lower numbers of some prairie butterflies along frequently mowed rights-of-way than within remnant tall-grass prairies. We also observed higher butterfly species richness along sites with more native plant species. By reducing mowing and spraying and reintroducing tall-grass prairie plants, urban rights-of-way could serve as extensive reservoirs for tall-grass prairie plants and butterflies in urban landscapes. Eventually, managing urban rights-of-way as reservoirs for tall-grass prairie plants and animals could contribute to the restoration of tall-grass prairie in the North American Midwest.

  16. The paradigm of tumor shrinkage and rapid liver remnant hypertrophy for conversion of initially unresectable colorectal liver metastasis: a case report and literature review.

    PubMed

    Xiao, Nan; Yu, Kailin; Yu, Shaojun; Wu, Jianjun; Wang, Jian; Shan, Siyang; Zheng, Shuchun; Wang, Liuhong; Wang, Jianwei; Peng, Shuyou

    2017-08-03

    For colorectal liver metastasis (CRLM) patients, hepatic resection is currently the sole cure offering the chance of long-term survival. Tumor shrinkage and planned liver remnant hypertrophy are the two key strategies for conversion of initially unresectable CRLM. First conducted in 2012, associated liver partition and portal vein ligation for staged hepatectomy (ALPPS) allows rapid liver growth. As a means to induce hypertrophy, portal vein embolization (PVE) has been widely applied before extending hepatectomy. Recently, Peng et al. present a new approach of terminal branches portal vein embolization (TBPVE), offering an efficient way to amplify FLR and making chances for surgery in 2 weeks. We reported a 61-year-old woman with synchronous hepatic metastasized carcinoma of the colon sigmoideum underwent TBPVE after 6 cycles of neoadjuvant therapy in order to perform a planned right trisectionectomy. Rapid liver remnant hypertrophy and remarkable tumor shrinkage were achieved, and laparoscopic sigmoidectomy and right trisectionectomy were successfully performed. The postsurgical course was uneventful and 7 months of recurrence-free survival have been witnessed. The dual tactics of tumor shrinkage and planned rapid liver remnant hypertrophy will make concerted efforts to further increase the clinical candidacy for curative resection, which are valuable for further investigation.

  17. Fermi LAT discovery of GeV gamma-ray emission from the young supernova remnan Cassiopeia A

    DOE PAGES

    Abdo, A. A.

    2010-01-27

    Here, we report on the first detection of GeV high-energy gamma-ray emission from a young supernova remnant (SNR) with the Large Area Telescope aboard the Fermi Gamma-ray Space Telescope. Our observations reveal a source with no discernible spatial extension detected at a significance level of 12.2σ above 500 MeV at a location that is consistent with the position of the remnant of the supernova explosion that occurred around 1680 in the Cassiopeia constellation—Cassiopeia A (Cas A). The gamma-ray flux and spectral shape of the source are consistent with a scenario in which the gamma-ray emission originates from relativistic particles acceleratedmore » in the shell of this remnant. The total content of cosmic rays (electrons and protons) accelerated in Cas A can be estimated as W CR sime (1-4) × 1049 erg thanks to the well-known density in the remnant assuming that the observed gamma ray originates in the SNR shell(s). Finally, the magnetic field in the radio-emitting plasma can be robustly constrained as B ≥ 0.1 mG, providing new evidence of the magnetic field amplification at the forward shock and the strong field in the shocked ejecta.« less

  18. ASCA Observations of LMC SNRS

    NASA Technical Reports Server (NTRS)

    Hughes, John P.

    1999-01-01

    We present our first results from a study of the supernova remnants (SNRs) in the Large Magellanic Cloud (LMC) using data from ASCA. The three remnants we have analyzed to date, 0509-67.5, 0519-69.0, and N103B, are among the smallest, and presumably also the youngest, in the Cloud. The X-ray spectra of these SNRs show strong K(alpha) emission lines of silicon, sulfur, argon, and calcium with no evidence for corresponding lines of oxygen, neon, or magnesium. The dominant feature in the spectra is a broad blend of emission lines around 1 keV which we attribute to L-shell emission lines of iron. Model calculations (Nomoto, Thielemann, & Yokoi 1984) show that the major products of nucleosynthesis in Type Ia supernovae (SNs) are the elements from silicon to iron, as observed here. The calculated nucleosynthetic yields from Type Ib and II SNs are shown to be qualitatively inconsistent with the data. We conclude that the SNs which produced these remnants were of Type Ia. This finding also confirms earlier suggestions that the class of Balmer-dominated remnants arise from Type Ia SN explosions. Based an these early results from the LMC SNR sample, we find that roughly one-half of the SNRs produced in the LMC within the last approximately 1500 yr came from Type Ia SNs.

  19. Urban Rights-of-Way as Reservoirs for Tall-Grass Prairie Plants and Butterflies

    NASA Astrophysics Data System (ADS)

    Leston, Lionel; Koper, Nicola

    2016-03-01

    Urban rights-of-way may be potential reservoirs of tall-grass prairie plants and butterflies. To determine if this is true, in 2007-2008, we conducted vegetation surveys of species richness and cover, and butterfly surveys of species richness and abundance, along 52 transmission lines and four remnant prairies in Winnipeg, Manitoba. We detected many prairie plants and butterflies within transmission lines. Some unmowed and infrequently managed transmission lines had native plant species richness and total percent cover of native plants comparable to that of similar-sized remnant tall-grass prairies in the region. Although we did not find significant differences in overall native butterfly numbers or species richness between rights-of-way and remnant prairies, we found lower numbers of some prairie butterflies along frequently mowed rights-of-way than within remnant tall-grass prairies. We also observed higher butterfly species richness along sites with more native plant species. By reducing mowing and spraying and reintroducing tall-grass prairie plants, urban rights-of-way could serve as extensive reservoirs for tall-grass prairie plants and butterflies in urban landscapes. Eventually, managing urban rights-of-way as reservoirs for tall-grass prairie plants and animals could contribute to the restoration of tall-grass prairie in the North American Midwest.

  20. A Chandra X-Ray Survey of Ejecta in the Cassiopeia A Supernova Remnant

    NASA Technical Reports Server (NTRS)

    Hwang, Una; Laming, J. Martin

    2011-01-01

    We present a survey of the X-ray emitting ejecta in the Cassiopeia A supernova remnant based on an extensive analysis of over 6000 spectral regions extracted on 2.5-10" angular scales using the Chandra 1 Ms observation. We interpret these results in the context of hydrodynamical models for the evolution of the remnant. The distributions of fitted temperature and ionization age are highly peaked and suggest that the ejecta were subjected to multiple secondary shocks. Based on the fitted emission measure and element abundances, and an estimate of the emitting volume, we derive masses for the X-ray emitting ejecta as well as showing the distribution of the mass of various elements over the remnant. The total shocked Fe mass appears to be roughly 0.14 Solar Mass, which accounts for nearly all of the mass expected in Fe ejecta. We find two populations of Fe ejecta, that associated with normal Si-burning and that associated with alpha-rich freeze-out, with a mass ratio of approximately 2:1. Surprisingly, essentially all of this Fe (both components) is well outside the central regions of the SNR, presumably having been ejected by hydrodynamic instabilities during the explosion. We discuss this, and its implications for the neutron star kick.

  1. [Landscape pattern and productivity characteristics of the oasis landscape ecosystem in Linze, Gansu, China].

    PubMed

    Liu, Xuelu; Ren, Jizhou; Zhang, Zihe

    2002-08-01

    Oasis landscape ecosystem is composed of 10 landscape elements, i.e., residence land, cultivated land, grassland, forestland, water area, water system, road, rocky desert, sandy desert, and gravel desert. Among the elements, cultivated land formed by human being production covers the most of the area, is most connected, and hence, is the matrix of the oasis landscape ecosystem. Residence land, grassland, forestland, water area, rocky desert, sandy desert, and gravel desert are patches. Residence land and forestland generate from human being production, while rocky desert, gravel desert and sandy desert are the remnant with the human being disturbance. Water region and grassland are the environmental resources remnant after natural disturbance. Water system and road are corridors. Cultivated land dominated in plant production should be utilized with more productive layers through developing animal production other than expanding used-area to maintain the landscape heterogeneity and diversity of the oasis landscape ecosystem. For remnant and environmental resource patches, it should be profitable in preserving and stabilizing landscape heterogeneity and diversity, exploiting the functions of water and soil conservation, tourism, windbreak and sand fixation. For landscape elements remnant only, it should be fruitful in avoiding degeneration of the landscape pattern to explore their preceding plant production with moderate plant production.

  2. Current status in remnant gastric cancer after distal gastrectomy

    PubMed Central

    Ohira, Masaichi; Toyokawa, Takahiro; Sakurai, Katsunobu; Kubo, Naoshi; Tanaka, Hiroaki; Muguruma, Kazuya; Yashiro, Masakazu; Onoda, Naoyoshi; Hirakawa, Kosei

    2016-01-01

    Remnant gastric cancer (RGC) and gastric stump cancer after distal gastrectomy (DG) are recognized as the same clinical entity. In this review, the current knowledges as well as the non-settled issues of RGC are presented. Duodenogastric reflux and denervation of the gastric mucosa are considered as the two main factors responsible for the development of RGC after benign disease. On the other hand, some precancerous circumstances which already have existed at the time of initial surgery, such as atrophic gastritis and intestinal metaplasia, are the main factors associated with RGC after gastric cancer. Although eradication of Helicobacter pylori (H. pylori) in remnant stomach is promising, it is still uncertain whether it can reduce the risk of carcinogenesis. Periodic endoscopic surveillance after DG was reported useful in detecting RGC at an early stage, which offers a chance to undergo minimally invasive endoscopic treatment or laparoscopic surgery and leads to an improved prognosis in RGC patients. Future challenges may be expected to elucidate the benefit of eradication of H. pylori in the remnant stomach if it could reduce the risk for RGC, to build an optimal endoscopic surveillance strategy after DG by stratifying the risk for development of RGC, and to develop a specific staging system for RGC for the standardization of the treatment by prospecting the prognosis. PMID:26937131

  3. Incidence of metachronous gastric cancer in the remnant stomach after synchronous multiple cancer surgery.

    PubMed

    Nozaki, Isao; Hato, Shinji; Kobatake, Takaya; Ohta, Koji; Kubo, Yoshirou; Nishimura, Rieko; Kurita, Akira

    2014-01-01

    In the preoperative evaluation for gastric cancer, high-resolution endoscopic technologies allow us to detect small accessory lesions. However, it is not known if the gastric remnant after partial gastrectomy for synchronous multiple gastric cancers has a greater risk for metachronous cancer. The purpose of this study was to determine the incidence of metachronous cancer in this patient subset compared with that after solitary cancer surgery. Data on a consecutive series of 1,281 patients gastrectomized for early gastric cancer from 1991 to 2007 were analyzed retrospectively. The 715 gastric remnants after distal gastrectomy were periodically surveyed by endoscopic examination in Shikoku Cancer Center. Among those surveyed cases, 642 patients were pathologically diagnosed with solitary lesion (SO group) and 73 patients with synchronous multiple lesions (MU group) at the time of the initial surgery. In the follow-up period, 15 patients in the SO group and 3 patients in the MU group were diagnosed as having metachronous cancer in the gastric remnant. The cumulative 4-year incidence rate was 1.9 % in the SO group and 5.5 % in the MU group. The difference did not reach the significant level by the log-rank test. The incidence of metachronous cancer is higher after multiple cancer surgery; however, the difference is not statistically significant.

  4. Patterns of Hierarchical Structure in the Medical Lexicon

    PubMed Central

    Michael, Patricia A.; Cole, William G.; Stewart, James; Blois, Marsden S.

    1987-01-01

    Concepts in basic and clinical medical science cover a wide range of levels of description, from the subatomic level to the level of the patient as a whole. Medical language may have usage regularities consistent with this hierarchical nature of medical knowledge. Preliminary studies of word occurrence in abstracts drawn from three medical journals representing three broadly defined levels of description (chemical system, physiologic system, and patient as a whole) demonstrated a nonuniform word usage, with many words unique to one or another journal. In this present study, word occurrence was examined in an expanded pool of medical text consisting of sixteen textbooks representing ten different levels of description: atom/ion, micromolecule, macromolecule, organelle, cell, tissue, organ, physiologic system, major body part (or multiple physiologic systems) and patient as a whole. Word usage was found to be nonuniform, with many words unique to specific levels. The presence of such usage regularities may provide a basis for facilitating the automatic classification and retrieval of medical text.

  5. Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling.

    PubMed

    Ermilov, Alexandre N; Kumari, Archana; Li, Libo; Joiner, Ariell M; Grachtchouk, Marina A; Allen, Benjamin L; Dlugosz, Andrzej A; Mistretta, Charlotte M

    2016-11-01

    For homeostasis, lingual taste papilla organs require regulation of epithelial cell survival and renewal, with sustained innervation and stromal interactions. To investigate a role for Hedgehog/GLI signaling in adult taste organs we used a panel of conditional mouse models to manipulate GLI activity within epithelial cells of the fungiform and circumvallate papillae. Hedgehog signaling suppression rapidly led to taste bud loss, papilla disruption, and decreased proliferation in domains of papilla epithelium that contribute to taste cells. Hedgehog responding cells were eliminated from the epithelium but retained in the papilla stromal core. Despite papilla disruption and loss of taste buds that are a major source of Hedgehog ligand, innervation to taste papillae was maintained, and not misdirected, even after prolonged GLI blockade. Further, vimentin-positive fibroblasts remained in the papilla core. However, retained innervation and stromal cells were not sufficient to maintain taste bud cells in the context of compromised epithelial Hedgehog signaling. Importantly taste organ disruption after GLI blockade was reversible in papillae that retained some taste bud cell remnants where reactivation of Hedgehog signaling led to regeneration of papilla epithelium and taste buds. Therefore, taste bud progenitors were either retained during epithelial GLI blockade or readily repopulated during recovery, and were poised to regenerate taste buds once Hedgehog signaling was restored, with innervation and papilla connective tissue elements in place. Our data argue that Hedgehog signaling is essential for adult tongue tissue maintenance and that taste papilla epithelial cells represent the key targets for physiologic Hedgehog-dependent regulation of taste organ homeostasis. Because disruption of GLI transcriptional activity in taste papilla epithelium is sufficient to drive taste organ loss, similar to pharmacologic Hedgehog pathway inhibition, the findings suggest that taste alterations in cancer patients using systemic Hedgehog pathway inhibitors result principally from interruption of signaling activity in taste papillae.

  6. Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling

    PubMed Central

    Mistretta, Charlotte M.

    2016-01-01

    For homeostasis, lingual taste papilla organs require regulation of epithelial cell survival and renewal, with sustained innervation and stromal interactions. To investigate a role for Hedgehog/GLI signaling in adult taste organs we used a panel of conditional mouse models to manipulate GLI activity within epithelial cells of the fungiform and circumvallate papillae. Hedgehog signaling suppression rapidly led to taste bud loss, papilla disruption, and decreased proliferation in domains of papilla epithelium that contribute to taste cells. Hedgehog responding cells were eliminated from the epithelium but retained in the papilla stromal core. Despite papilla disruption and loss of taste buds that are a major source of Hedgehog ligand, innervation to taste papillae was maintained, and not misdirected, even after prolonged GLI blockade. Further, vimentin-positive fibroblasts remained in the papilla core. However, retained innervation and stromal cells were not sufficient to maintain taste bud cells in the context of compromised epithelial Hedgehog signaling. Importantly taste organ disruption after GLI blockade was reversible in papillae that retained some taste bud cell remnants where reactivation of Hedgehog signaling led to regeneration of papilla epithelium and taste buds. Therefore, taste bud progenitors were either retained during epithelial GLI blockade or readily repopulated during recovery, and were poised to regenerate taste buds once Hedgehog signaling was restored, with innervation and papilla connective tissue elements in place. Our data argue that Hedgehog signaling is essential for adult tongue tissue maintenance and that taste papilla epithelial cells represent the key targets for physiologic Hedgehog-dependent regulation of taste organ homeostasis. Because disruption of GLI transcriptional activity in taste papilla epithelium is sufficient to drive taste organ loss, similar to pharmacologic Hedgehog pathway inhibition, the findings suggest that taste alterations in cancer patients using systemic Hedgehog pathway inhibitors result principally from interruption of signaling activity in taste papillae. PMID:27893742

  7. On the origin of Triton and Pluto

    NASA Technical Reports Server (NTRS)

    Mckinnon, W. B.

    1984-01-01

    Lyttleton's (1936) hypothesis that Triton and Pluto originated as adjacent prograde satellites of Neptune is evaluated, and it is shown that with the presently accepted masses of Triton and Pluto-Charon, the momentum and energy exchange required to set Triton on a retrograde orbit is impossible. The Pluto-Charon system could not have acquired its present angular momentum state during an ejection event unless a physical collision was involved, which is quite unlikely. The simplest hypothesis is that Triton and Pluto are independent representatives of large outer solar system planetesimals. Triton is simply captured, with spectacular consequences that include runaway melting of interior ices and release to the surface of clathrated CH4, CO, and N2. Condensed remnants of this protoatmosphere could account for features in Triton's unique spectrum.

  8. On the Origin of Triton and Pluto

    NASA Technical Reports Server (NTRS)

    Mckinnon, W. B.

    1985-01-01

    Lyttleton's (1936) hypothesis that Triton and Pluto originated as adjacent prograde satellites of Neptune is evaluated, and it is shown that with the presently accepted masses of Triton and Pluto-Charon, the momentum and energy exchange required to sell Triton on a retrograde orbit is impossible. The Pluto-Charon system could not have acquired its present angular momentum state during an ejection event unless a physical collision was involved, which is quite unlikely. The simplest hypothesis is that Triton and Pluto are independent representatives of large outer solar system planetesimals. Triton is simply captured, with spectacular consequences that include runaway melting of interior ices and release to the surface of clathrated CH4, CO, and N2. Condensed remnants of this protoatmosphere could account for features in Triton's unique spectrum.

  9. Conservation: Where we stand: Review of Water, land, and people

    USGS Publications Warehouse

    Leopold, Luna Bergere

    1951-01-01

    A distinguished conservationist, just returned from more than a year in those Pacific islands held in trust by the United States, reports that representatives of the government there are nearly completely concerned with the maintenance of an administrative organization. Actual advances in matters of land use, of maintaining the material and mental welfare of the native population, and the preservation of the most interesting remnants of untouched habitat, are just never made.Any such oversimplification is, of course, subject to error in detail, but it nevertheless stands as a touchstone to where we stand in conservation. In much more guarded phrases, and with considerable supporting data, Bernard Frank and Anthony Netboy say much the same thing about governmental conservation in the United States in their recently published Water, Land, and People.

  10. Supernova Remnant Evolving in Wind-Blown Bubbles: A Case Study of Kes 27

    NASA Astrophysics Data System (ADS)

    Li, Jiangtao

    2013-10-01

    Mixed-morphology (MM) SNRs represent SN explosion in wind-blown bubbles. They are thus good places to study the interaction between massive stellar winds, SNRs, and the surrounding ISM. We propose a 50ks XMM-Newton observation of a peculiar MM SNR, Kes 27. We will map out the spectral parameters in tessellated meshes and construct EW maps of some emission lines with our newly developed spatially-resolved spectroscopy method. These analyses will help us to understand the unusual properties of this MM SNR, such as the X-ray bright outer shell, shell-like interior, and strong NE-SW asymmetry in morphology. We will also search for evidence of over-ionization state plasma and coherent X-ray features associated with the shell of the HI cavity.

  11. Cascade of Solitonic Excitations in a Superfluid Fermi Gas: From Solitons and Vortex Rings to Solitonic Vortices

    NASA Astrophysics Data System (ADS)

    Ku, Mark; Mukherjee, Biswaroop; Yefsah, Tarik; Zwierlein, Martin

    2015-05-01

    We follow the evolution of a superfluid Fermi gas of 6Li atoms following a one-sided π phase imprint. Via tomographic imaging, we observe the formation of a planar dark soliton, and its subsequent snaking and decay into a vortex ring. The latter eventually breaks at the boundary of the superfluid, finally leaving behind a single, remnant solitonic vortex. The nodal surface is directly imaged and reveals its decay into a vortex ring via a puncture of the initial soliton plane. At intermediate stages we find evidence for more exotic structures resembling Φ-solitons. The observed evolution of the nodal surface represents dynamics that occurs at the length scale of the interparticle spacing, thus providing new experimental input for microscopic theories of strongly correlated fermions.

  12. The Formation of a Socioeconomic Health Disparity: The Case of Cocaine Use during the 1980s and 1990s*

    PubMed Central

    MIECH, RICHARD

    2017-01-01

    Despite the substantial and prolonged sociological interest in health disparities, much remains unknown about the processes that initiate them. To investigate this topic, we focus on the case study of cocaine use, for which a socioeconomic disparity emerged across all age groups in a short period of time around 1990. We examine whether the newly-formed disparity represents a selective remnant of previous users or, instead, a selective recruitment of new users. To evaluate these two potential processes we use latent class regression on a nationally representative cohort with repeated measures of past-year cocaine use before and after1990. Results support the “remnant” hypothesis and show that the newly-formed disparity resulted primarily because people in the lower social strata were less likely to have a trajectory of cocaine use with a sharp drop in use after 1990. These results point to the “remnant” concept as a way to bring together disparity analysis of very different and diverse health outcomes. PMID:18771068

  13. Soldier Performance as a Function of Stress and Load: A Review

    DTIC Science & Technology

    1990-01-01

    1985) increasing load obstacle course decreased weight performance Ikai & Steinhaus shouting forearm flex strength increased (1961) gun shot increased...performance. Capacity represents relatively fil1 ed physiological limits of behavior, while performance is a function of psychological factors (Ikai & Steinhaus ...3), 513-524. Ikai, M., & Steinhaus , A. H. (1961). Some factors modifying the expression of human strength. Journal of ADnlied Physiology, 15, 157-163

  14. Mercury: Aspects of its ecology and environmental toxicity. [physiological effects of mercury compound contamination of environment

    NASA Technical Reports Server (NTRS)

    Siegel, S. M.

    1973-01-01

    A study was conducted to determine the effects of mercury pollution on the environment. The possible sources of mercury contamination in sea water are identified. The effects of mercury on food sources, as represented by swordfish, are analyzed. The physiological effects of varying concentrations of mercury are reported. Emphasis is placed on the situation existing in the Hawaiian Islands.

  15. A study of potential Olympic swimmers: I, the starting point.

    PubMed Central

    Bagnall, K. M.; Kellett, D. W.

    1977-01-01

    Physiological and anthropometric profiles of a group of successful young swimmers are presented. Anthropometrically the swimmers appear to fall within fairly narrow limits but are physically more mature than their peers. Physiologically there is greater diversity within the group representing perhaps the varying demands of the swimming events practised. All values for the physiological parameters measured are high compared with children of similar ages. For the future it is hoped to relate performance in swimming to the variables measured and to assess any changes which occur thus perhaps colouring the profiles presented here. PMID:922274

  16. Nonlinear dynamics, fractals, cardiac physiology and sudden death

    NASA Technical Reports Server (NTRS)

    Goldberger, Ary L.

    1987-01-01

    The authors propose a diametrically opposite viewpoint to the generally accepted tendency of equating healthy function with order and disease with chaos. With regard to the question of sudden cardiac death and chaos, it is suggested that certain features of dynamical chaos related to fractal structure and fractal dynamics may be important organizing principles in normal physiology and that certain pathologies, including ventricular fibrillation, represent a class of 'pathological periodicities'. Some laboratory work bearing on the relation of nonlinear analysis to physiological and pathophysiological data is briefly reviewed, with tentative theories and models described in reference to the mechanism of ventricular fibrillation.

  17. Approaches for the Application of Physiologically Based ...

    EPA Pesticide Factsheets

    EPA released the final report, Approaches for the Application of Physiologically Based Pharmacokinetic (PBPK) Models and Supporting Data in Risk Assessment as announced in a September 22 2006 Federal Register Notice.This final report addresses the application and evaluation of PBPK models for risk assessment purposes. These models represent an important class of dosimetry models that are useful for predicting internal dose at target organs for risk assessment applications. EPA is releasing a final report describing the evaluation and applications of physiologically based pharmacokinetic (PBPK) models in health risk assessment. This was announced in the September 22 2006 Federal Register Notice.

  18. Investigation of photolithography process on SPOs for the Athena mission

    NASA Astrophysics Data System (ADS)

    Massahi, S.; Girou, D. A.; Ferreira, D. D. M.; Christensen, F. E.; Jakobsen, A. C.; Shortt, B.; Collon, M.; Landgraf, B.

    2015-09-01

    As part of the ongoing effort to optimize the throughput of the Athena optics we have produced mirrors with a state-of-the-art cleaning process. We report on the studies related to the importance of the photolithographic process. Pre-coating characterization of the mirrors has shown and still shows photoresist remnants on the SiO2- rib bonding zones, which influences the quality of the metallic coating and ultimately the mirror performance. The size of the photoresist remnants is on the order of 10 nm which is about half the thickness of final metallic coating. An improved photoresist process has been developed including cleaning with O2 plasma in order to remove the remaining photoresist remnants prior to coating. Surface roughness results indicate that the SiO2-rib bonding zones are as clean as before the photolithography process is performed.

  19. Convective Excitation of Inertial Modes in Binary Neutron Star Mergers

    NASA Astrophysics Data System (ADS)

    De Pietri, Roberto; Feo, Alessandra; Font, José A.; Löffler, Frank; Maione, Francesco; Pasquali, Michele; Stergioulas, Nikolaos

    2018-06-01

    We present the first very long-term simulations (extending up to ˜140 ms after merger) of binary neutron star mergers with piecewise polytropic equations of state and in full general relativity. Our simulations reveal that, at a time of 30-50 ms after merger, parts of the star become convectively unstable, which triggers the excitation of inertial modes. The excited inertial modes are sustained up to several tens of milliseconds and are potentially observable by the planned third-generation gravitational-wave detectors at frequencies of a few kilohertz. Since inertial modes depend on the rotation rate of the star and they are triggered by a convective instability in the postmerger remnant, their detection in gravitational waves will provide a unique opportunity to probe the rotational and thermal state of the merger remnant. In addition, our findings have implications for the long-term evolution and stability of binary neutron star remnants.

  20. Supernova remnant evolution in wind bubbles: A closer look at Kes 27

    NASA Astrophysics Data System (ADS)

    Dwarkadas, V. V.; Dewey, D.

    2013-03-01

    Massive Stars (>8M⊙) lose mass in the form of strong winds. These winds accumulate around the star, forming wind-blown bubbles. When the star explodes as a supernova (SN), the resulting shock wave expands within this wind-blown bubble, rather than the interstellar medium. The properties of the resulting remnant, its dynamics and kinematics, the morphology, and the resulting evolution, are shaped by the structure and properties of the wind-blown bubble. In this article we focus on Kes 27, a supernova remnant (SNR) that has been proposed by [1] to be evolving in a wind-blown bubble, explore its properties, and investigate whether the X-Ray properties could be ascribed to evolution of a SNR in a wind-blown bubble. Our initial model does not support the scenario proposed by [1], due to the fact that the reflected shock is expanding into much lower densities.

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